Surgical treatment of tuberculous spondylodiscitis.
BACKGROUND
Most patients affected by spinal tuberculosis can be successfully treated conservatively with chemotherapy, external bracing and prolonged rest. Nevertheless, kyphotic deformity, spinal instability and neurological deficit remain a common complication associated with conservative approach.


OBJECTIVE
To illustrate different indications and treatment modalities for tuberculous spondylodiscitis, focusing on the role of surgery as an adjuvant of effective chemotherapy in the management of selected patients.


METHODS
Various early and late surgical procedures are recommended to treat spinal tuberculosis. The Authors analyzed surgical indications, approaches, complications and outcomes comparing their experience with available Literature.


RESULTS
Conservative management is preferable in patients without vertebral instability and deformity; in presence of abscesses, invasive radiological techniques in combination with abscess drainage and chemotherapy are recommended. In patients with vertebral collapse, kyphotic deformity or abscess formation, vertebral instability or neurological deficits, anterior radical debridement, anterior strut grafting and anterior instrumentation is an optimal standardized procedure. In patients with involvement of more than two vertebral levels or lumbosacral junction and in those whose sagittal alignment is markedly deformed with segmental kyphosis, and in patients who have difficulty in undergoing anterior instrumentation, posterior instrumentation is recommended in combination with anterior radical debridement and anterior strut grafting in one or two staged procedures.


CONCLUSIONS
Since surgery for spinal tuberculosis is demanding, it should be performed only after taking into account the risks and benefits in operable patients. Various surgical procedures are recommended to treat spinal tuberculosis but the common goals are to eradicate the infection and to prevent or to treat neurologic deficits or spinal deformity.
Division of Spinal Surgery, Department of Orthopaedics and Traumatology, School of Medicine, Catholic University of the Sacred Heart, Rome, Italy. enrico.pola@rm.unicatt.it
E
E
Pola
B
B
Rossi
L A
LA
Nasto
D
D
Colangelo
C A
CA
Logroscino
D015299:Discitis / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery; D006801:Humans; D007403:Intervertebral Disc / Q000382:microbiology / Q000601:surgery*; D009169:Mycobacterium tuberculosis / Q000472:pathogenicity; D019637:Orthopedic Procedures / Q000009:adverse effects / Q000295:instrumentation; D010019:Osteomyelitis / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery; D018579:Patient Selection; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome; D014399:Tuberculosis, Spinal / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery*