Vertebral body osteolysis following the use of bone morphogenetic protein in spinal surgery: a mimicker of infection.
This report describes the imaging findings in three patients who developed lumbar spine osteolysis after posterior spinal fusion using rhBMP-2. These cases demonstrate the variable course of osteolysis, as well as the importance of recognizing its radiological appearances to prevent confusion with infection following spinal fusion.
Jackson Memorial Hospital, University of Miami Miller School of Medicine, 1611 NW 12th Avenue, Miami, FL 33136, USA. gsaigal@med.miami.edu
Gaurav
G
Saigal
Robert
R
Quencer
James D
JD
Guest
Mircea M
MM
Cristescu
Nathan
N
Lebwohl
D019485:Bone Morphogenetic Proteins / Q000009:adverse effects* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000175:diagnosis* / Q000209:etiology*; D013122:Spinal Diseases / Q000175:diagnosis* / Q000209:etiology*; D013123:Spinal Fusion / Q000009:adverse effects*; D013166:Spondylitis / Q000175:diagnosis / Q000209:etiology
D019485:Bone Morphogenetic Proteins