Microbial transformations of 7-hydroxyflavanone.
Microbial transformations of racemic 7-hydroxyflavanone using strains of genus Aspergillus (A. niger KB, A. niger 13/5, A. ochraceus 456) and the species Penicillium chermesinum 113 were studied. The products of O-methylation, O-methylation along with hydroxylation at C-3' and C-4', reduction of the carbonyl group, reduction of the carbonyl group along with hydroxylation at C-5, and dehydrogenation of C-2 and C-3 were obtained. Most of the products (with the exception of the O-methylation one) have stronger antioxidant properties than the initial substrate.
Department of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, Poland. ekostrzew@gmail.com
Edyta
E
Kostrzewa-Susłow
Tomasz
T
Janeczko
D000975:Antioxidants / Q000378:metabolism; D001230:Aspergillus / Q000378:metabolism*; D044950:Flavanones / Q000378:metabolism*; D006900:Hydroxylation; D010407:Penicillium / Q000378:metabolism*
D000975:Antioxidants; D044950:Flavanones; C059353:7-hydroxyflavanone