A color-coding amacrine cell may provide a blue-off signal in a mammalian retina.
Retinal amacrine cells are thought to lack chromatic or color-selective light responses and have only a minor role in color processing. We found that a type of mammalian (Ictidomys tridecemlineatus) amacrine cell selectively carries a blue-On signal, which is received from a blue or short wavelength-sensitive (S) cone On bipolar cell. This glycinergic inhibitory S-cone amacrine cell is ideally placed for driving blue-Off responses in downstream ganglion cells.
Unit on Retinal Neurophysiology, National Eye Institute, US National Institutes of Health, Bethesda, Maryland, USA.
Shan
S
Chen
Wei
W
Li
D025042:Amacrine Cells / Q000502:physiology* / Q000648:ultrastructure; D000818:Animals; D003118:Color Perception / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology; D009900:Optic Nerve / Q000502:physiology*; D009924:Organ Culture Techniques; D010775:Photic Stimulation / Q000379:methods*; D012160:Retina / Q000166:cytology / Q000502:physiology / Q000648:ultrastructure; D012589:Sciuridae; D015398:Signal Transduction / Q000502:physiology*; D055366:Synaptic Potentials / Q000502:physiology*