Epidemiological analysis and use of rapid urease test in patients with perforated peptic ulcers.
OBJECTIVE
To analyze the epidemiological profile of patients with gastroduodenal ulcer perforation and verify if the presence of H. pylori in the peritoneal and intraluminal secretions of these patients can be assessed by rapid urease test.


METHODS
We conducted a prospective, descriptive, cross-sectional study with data from patients in a hospital at a regional level, in patients with peptic ulcer. During surgery, we collected peritoneal fluid samples (in the vicinity of the perforation) and intraluminal secretion, sending them for culture and rapid urease test.


RESULTS
Fourteen patients were analyzed. The average age was 41.06 years, all men, Whites (71.4%), smokers (57.2%), BMI <30 (85.7%), with a history of dyspepsia (78.6%). Serology for H. pylori was positive in 84.6% of cases. The rapid urease test was positive in 78.6% of the samples of the digestive tract and 42.8% of samples from the peritoneal cavity; 41.6% were positive at both sites, 50% only in the digestive cavity and 8.4% only in the peritoneal cavity. Of the 11 patients with positive serology for H. pylori, 100% were positive in at least one of the sites surveyed.


CONCLUSIONS
It was found that the incidence was lower than expected. There is significant association between infection with H. pylori and the occurrence of perforation. The presence of this pathogen can be assessed both by serology and by the realization of the rapid urease test from fluid collected in the peritoneal cavity and the gastric / duodenal lumen.
Medical Residency Program in General Surgery of the Miranda Gomes Homer Regional Hospital, São José County, Santa Catarina State, Brazil. jairocasali@gmail.com
Jairo Júnior
JJ
Casali
Orli
O
Franzon
Nicolau Fernandes
NF
Kruel
Bruno Duarte
BD
Neves
D000328:Adult; D004796:Clinical Enzyme Tests; D003430:Cross-Sectional Studies; D006801:Humans; D008297:Male; D010439:Peptic Ulcer Perforation / Q000175:diagnosis* / Q000453:epidemiology*; D011446:Prospective Studies; D014510:Urease / Q000032:analysis*; D055815:Young Adult
D014510:Urease