Separation of nanoparticles in aqueous multiphase systems through centrifugation.
This paper demonstrates the use of aqueous multiphase systems (MuPSs) as media for rate-zonal centrifugation to separate nanoparticles of different shapes and sizes. The properties of MuPSs do not change with time or during centrifugation; this stability facilitates sample collection after separation. A three-phase system demonstrates the separation of the reaction products (nanorods, nanospheres, and large particles) of a synthesis of gold nanorods, and enriches the nanorods from 48 to 99% in less than ten minutes using a benchtop centrifuge.
Departments of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
Ozge
O
Akbulut
Charles R
CR
Mace
Ramses V
RV
Martinez
Ashok A
AA
Kumar
Zhihong
Z
Nie
Matthew R
MR
Patton
George M
GM
Whitesides