Phase I and II biotransformation enzymes and polycyclic aromatic hydrocarbons in the Mediterranean mussel (Mytilus galloprovincialis, Lamarck, 1819) collected in front of an oil refinery.
The aim of the present study was to investigate the responses of phase I and II biotransformation enzymes and levels of PAHs in the Mediterranean mussel (Mytilus galloprovincialis, Lamarck, 1819) collected from three sites at different distance from an oil refinery. Phase I enzyme activities as NAD(P)H-cyt c red, NADH ferry red, B(a)PMO and phase II as UDPGT, GST were measured in digestive gland while 16 PAHs (US-EPA) in whole soft tissue. An added value to the data obtained in the present study rely on the RDA analysis which showed close correlations between PAHs levels and phase I enzyme activities in mussels collected in front of the refinery. And again a significant spatial correlation between B(a)P levels and NADPH-cyt c red activities was observed using linear models. No differences among sites for B(a)PMO and phase II GST activities were observed, while the application of UDPGT as biomarkers requires further investigation.
Department of Environmental Sciences G. Sarfatti, University of Siena, Via Mattioli 4, 53100 Siena, Italy. trisciani8@unisi.it
Anna
A
Trisciani
Guido
G
Perra
Tancredi
T
Caruso
Silvano
S
Focardi
Ilaria
I
Corsi
D000818:Animals; D002617:Chemical Industry; D004064:Digestive System / Q000201:enzymology; D004789:Enzyme Activation; D049878:Mytilus / Q000737:chemistry* / Q000201:enzymology*; D010578:Petroleum; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis*
D010578:Petroleum; D011084:Polycyclic Aromatic Hydrocarbons; D014874:Water Pollutants, Chemical