Ovarian germ cell neoplasm in a true hermaphrodite.
True hermaphrodites are extremely rare. The incidence of malignancies in cases of true hermaphrodites range between 1.9-2.6%, and is almost exclusively associated with cytogenetic mosaicism. All of the malignancies reported till date are germ cell neoplasms, namely, seminoma, gonadoblastoma or teratoma, mostly in the male phenotype. In this case we Illustrate a rare occurrence of a dysgerminoma of the ovary, its treatment and responses, in a 35-year-old true hermaphrodite with a female phenotype, and cytogenetic mosaicism.
Department of Radiotherapy, RG Kar Medical College, Kolkata 700004.
Srikrishna
S
Mondal
Koushik
K
Chatterjee
Subir Kumar
SK
Bhattacharya
Shankar Kumar
SK
Nath
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D012734:Disorders of Sex Development / Q000235:genetics*; D004407:Dysgerminoma / Q000175:diagnosis / Q000628:therapy*; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D009030:Mosaicism; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000628:therapy*
D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin