[Maternal mortality and impact of dengue in Southeast Brazil: an ecological study, 2001-2005].
The aim of this study was to explore the distribution of reproductive outcomes following dengue virus infection during pregnancy (2001-2005). An ecological epidemiological study was conducted in all counties with more than 80,000 inhabitants in Southeast Brazil. The study explored the correlation between dengue incidence rates in women 15-39 years of age and selected mortality indicators (maternal, fetal, perinatal, neonatal, early neonatal, and infant) in these counties, and Spearman correlation coefficients were calculated. A positive correlation was observed between median dengue incidence in women 15-39 years of age and median maternal mortality (r = 0.88; 95%CI: 0.51; 1.00), with a determination coefficient R² = 0.78. The correlation between dengue incidence in childbearing-age women and reproductive outcomes in Southeast Brazil suggests that dengue infection during pregnancy can negatively impact its outcome and increase maternal mortality.
Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz, Rio de Janeiro, Brasil. annekarinmm@gmail.com
Anne Karin Madureira da
AK
Mota
Adalberto Luiz
AL
Miranda Filho
Valéria
V
Saraceni
Sergio
S
Koifman
D000293:Adolescent; D000328:Adult; D001938:Brazil / Q000453:epidemiology; D003715:Dengue / Q000150:complications / Q000453:epidemiology* / Q000401:mortality; D005260:Female; D005313:Fetal Death / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007226:Infant Mortality; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008428:Maternal Mortality; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000401:mortality* / Q000821:virology; D012307:Risk Factors; D055815:Young Adult