[Clinical analysis of combined organ resection for T4b gastric cancer].
OBJECTIVE
To evaluate the outcomes of combined organ resection for T4b gastric cancer, and determine the operative indication and prognostic factors.


METHODS
Clinical data of 96 cases with T4bN0-3bM0 gastric cancer treated with combined organ resection in Tianjin Cancer Hospital from 2001 to 2005 were analyzed retrospectively.


RESULTS
Twelve patients developed postoperative complications, including pancreatic fistula (n=4), abdominal infection(n=5), pulmonary infection(n=3), all of which were managed with conservative treatment. There were no perioperative deaths. All the patients had postoperative follow up with a median of 73 months. The 1-, 3-, 5-year overall survival rates were 70.5%, 42.1%, and 23.5%, respectively. Univariate analysis showed that Borrmann type, histologic type, lymph node staging, and pancreatic invasion were associated with the survival in patients with T4b gastric cancer(both P<0.05). Multivariable analysis showed that lymph node staging and histologic type were independent prognostic factors(all P<0.05).


CONCLUSIONS
For well differentiated gastric cancer with lymph node staging of pN0 or pN1, combined organ resection may offer survival benefit.
Department of Gastric Cancer, Tianjin Medical University, Tianjin, China.
Ming-zhi
MZ
Cai
Han
H
Liang
Xiao-na
XN
Wang
Li
L
Zhang
Liang-liang
LL
Wu
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000601:surgery*; D016896:Treatment Outcome