Do not miss rifampicin-induced thrombocytopenic purpura.
Drug-induced immune thrombocytopenia (DITP) can be triggered by a wide range of medications. Although many cases of DITP are mild, some are characterised by life-threatening bleeding symptoms. In the treatment of tuberculosis there are special therapeutic problems related to adverse effects of drugs, compliance to treatment and microbial resistance. Thrombocytopenia is an uncommon but potentially fatal adverse effect of certain antituberculous drugs when the incriminating drug is taken by a susceptible individual. Here the authors report a case of rifampicin-induced thrombocytopenia, which although rare, needs attention.
Department of Internal Medicine, CSM Medical University, Lucknow, Uttar Pradesh, India. icuexpert@gmail.com
Avinash
A
Agrawal
Manish
M
Gutch
Nirdesh
N
Jain
Ambukeshwar
A
Singh
D000328:Adult; D000904:Antibiotics, Antitubercular / Q000009:adverse effects* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010996:Pleural Effusion / Q000188:drug therapy; D011696:Purpura, Thrombocytopenic / Q000139:chemically induced* / Q000175:diagnosis; D012293:Rifampin / Q000009:adverse effects* / Q000627:therapeutic use
D000904:Antibiotics, Antitubercular; D012293:Rifampin