Tacrolimus induced diabetic ketoacidosis in nephrotic syndrome.
Tacrolimus, a reversible calcineurin inhibitor, is known for its diabetogenic potential. The incidence of diabetes is less frequent among the patients of nephrotic syndrome in comparison to organ transplant recipients. Diabetic ketoacidosis (DKA) is even rarer. DKA as the first presentation of new onset tacrolimus induced transient type 1 diabetes despite a lower dose range and low trough level of the drug is being reported in a 12-y-old girl with steroid resistant nephrotic syndrome.
Department of Pediatrics, IPGME&R, Kolkata, West Bengal, India. sumantra.com@gmail.com
Sumantra
S
Sarkar
Rakesh
R
Mondal
Madhumita
M
Nandi
Anjan Kumar
AK
Das
D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000139:chemically induced*; D016883:Diabetic Ketoacidosis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D009404:Nephrotic Syndrome / Q000188:drug therapy*; D016559:Tacrolimus / Q000009:adverse effects*
D007166:Immunosuppressive Agents; D016559:Tacrolimus