American trypanosomiasis (Chagas disease).
Chagas disease, also known as American trypanosomiasis, is a chronic infection caused by Trypanosoma cruzi, a protozoan parasite. It is transmitted to human beings mainly through the feces of infected triatomine bugs. The disease affects an estimated 8 to 10 million people in the Americas, putting them at risk of developing life-threatening cardiac and gastrointestinal complications. This article provides a brief update on the epidemiology, clinical manifestations, diagnosis, and treatment of Chagas disease.
Division of Cardiology, Anis Rassi Hospital, Avenida José Alves 453, Setor Oeste, Goiânia, GO 74110-020, Brazil. arassijr@terra.com.br
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Anis
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Marcondes de Rezende
D014355:Chagas Disease / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy; D002908:Chronic Disease; D006801:Humans; D009547:Nifurtimox / Q000009:adverse effects / Q000627:therapeutic use; D009593:Nitroimidazoles / Q000009:adverse effects / Q000627:therapeutic use; D014344:Trypanocidal Agents / Q000009:adverse effects / Q000627:therapeutic use; D014349:Trypanosoma cruzi / Q000472:pathogenicity
D009593:Nitroimidazoles; D014344:Trypanocidal Agents; D009547:Nifurtimox; C009999:benzonidazole