Listeria monocytogenes: no spreading without NO.
In infectious disease immunology, inducible nitric oxide (NO) synthase-derived NO is believed to function primarily as an antimicrobial and immunoregulatory molecule. In this issue of Immunity, Cole et al. (2012) show that NO helps the intracellular bacteria Listeria monocytogenes to spread.
Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Friedrich-Alexander-Universität Erlangen-Nürnberg und Universitätsklinikum Erlangen, 91054 Erlangen, Germany. christian.bogdan@uk-erlangen.de
Christian
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Bogdan