Electrocatalytic response of poly(cobalt tetraaminophthalocyanine)/multi-walled carbon nanotubes-Nafion modified electrode toward sulfadiazine in urine.
A highly sensitive amperometric sulfadiazine sensor fabricated by electrochemical deposition of poly(cobalt tetraaminophthalocyanine) (poly(Co(II)TAPc)) on the surface of a multi-walled carbon nanotubes-Nafion (MWCNTs-Nafion) modified electrode is described. This electrode showed a very attractive performance by combining the advantages of Co(II)TAPc, MWCNTs, and Nafion. Compared with the bare glassy carbon electrode (GCE) and the MWCNTs-Nafion modified electrode, the electrocatalytic activity of poly(Co(II)TAPc)-coated MWCNTs-Nafion GCE generated greatly improved electrochemical detections toward sulfadiazine including low oxidation potential, high current responses, and good anti-fouling performance. The oxidation peak currents of sulfadiazine obtained on the new modified electrode increased linearly while increasing the concentration of sulfadiazine from 0.5 to 43.5 μmol/L with the detection limit of 0.17 μmol/L.
Department of Chemistry, Zhejiang University, Hangzhou 310028, China.
Xiao-ping
XP
Hong
Yan
Y
Zhu
Yan-zhen
YZ
Zhang
D000890:Anti-Infective Agents / Q000652:urine; D003035:Cobalt; D055664:Electrochemical Techniques / Q000379:methods*; D005465:Fluorocarbon Polymers; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008855:Microscopy, Electron, Scanning; D037742:Nanotubes, Carbon / Q000648:ultrastructure; D010084:Oxidation-Reduction; D011108:Polymers; D013411:Sulfadiazine / Q000652:urine*
D000890:Anti-Infective Agents; D005465:Fluorocarbon Polymers; D037742:Nanotubes, Carbon; D011108:Polymers; D013411:Sulfadiazine; C040402:perfluorosulfonic acid; D003035:Cobalt