Resolution of severe hepato-pulmonary syndrome following transjugular portosystemic shunt procedure.
The hepato-pulmonary syndrome (HPS) is a relatively common complication of hepatic disease that leads to hypoxaemia and dyspnoea secondary to pulmonary shunting. A number of pharmacological therapies have been trialled, yet liver transplantation remains the only definitive treatment. The use of a transjugular intrahepatic portosystemic shunt (TIPS) to reduce portal hypertension and improve oxygenation remains controversial in HPS due to the lack of large clinical series or randomised controlled trials. We present a case of HPS successfully treated with TIPS and review the relevant literature.
Department of Gastroenterology and Hepatology, Royal Perth Hospital, Perth, Western Australia, Australia. michael.wallace2@health.wa.gov.au
Michael C
MC
Wallace
Alan L
AL
James
Martin
M
Marshall
Nickolas
N
Kontorinis
D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D020065:Hepatopulmonary Syndrome / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D017082:Portal Pressure / Q000502:physiology*; D019168:Portasystemic Shunt, Transjugular Intrahepatic / Q000379:methods*; D049268:Positron-Emission Tomography; D020127:Recovery of Function; D014057:Tomography, X-Ray Computed