Vulvar and vaginal cancer.
Vulvar cancer is becoming more common as the population ages and is primarily a disease of the elderly. Most vulvar cancers are diagnosed at a localized stage and can be cured with surgery and adjuvant radiotherapy. More conservative therapy has been the mainstay in vulvar cancer treatment, which has lessened short-term and long-term morbidity without sacrificing efficacy. Recent national and international studies continue to prove the value of sentinel lymph node technology, which is moving toward a new standard of care for women with early stage vulvar cancer. Vaginal cancer is a rare cancer that also affects elderly women. Prognosis is poor; however, adequate treatment can be delivered with a combination of external beam radiotherapy and brachytherapy, and with surgical resection for a select group of patients.
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Women's Health, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Jori S
JS
Carter
Levi S
LS
Downs
D000328:Adult; D000368:Aged; D001918:Brachytherapy; D002280:Basal Cell Carcinoma / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D018289:Carcinoma, Verrucous / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D015994:Incidence; D008010:Lichen Planus / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D018459:Lichen Sclerosus et Atrophicus / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D008545:Melanoma / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D008875:Middle Aged; D010145:Paget Disease, Extramammary / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D021701:Sentinel Lymph Node Biopsy; D014481:United States / Q000453:epidemiology; D014625:Vaginal Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D014846:Vulvar Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000628:therapy