The onchocerciasis chronicle: from the beginning to the end?
The year 2012 marks the 25th anniversary of the donation of ivermectin to fight onchocerciasis and the projected date for elimination of transmission of the disease in the Americas. This review looks at the history of onchocerciasis, from its discovery through to 2025, by which time it is projected that the disease will have been eliminated as a public health problem, except in a handful of sub-Saharan countries, where it should be well on the way towards elimination.
The Kitasato Institute and Kitasato University, 5-9-1 Shirokane, Minato-Ku, Tokyo 108-8641, Japan.
Andy
A
Crump
Carlos M
CM
Morel
Satoshi
S
Omura
D000818:Animals; D003695:Delivery of Health Care / Q000458:organization & administration; D060740:Disease Eradication / Q000379:methods / Q000458:organization & administration; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007300:Insect Control / Q000379:methods; D007559:Ivermectin / Q000627:therapeutic use*; D009854:Onchocerca / Q000302:isolation & purification / Q000472:pathogenicity* / Q000502:physiology; D009855:Onchocerciasis / Q000188:drug therapy / Q000453:epidemiology / Q000266:history / Q000517:prevention & control*; D012843:Simuliidae / Q000187:drug effects / Q000469:parasitology
D007559:Ivermectin