[Calcium-phosphorus ratio in relapse of peptic ulcer disease].
OBJECTIVE
To determine the metabolism of calcium and phosphorus in the period of peptic ulcer recurrence and to compare it with gastric secretion and motility.


METHODS
150 patients with peptic ulcer recurrence were examined. Apart from clinical and endoscopic examinations, the presence of calcium and phosphorus in blood and urine was detected, gastric secretion and motility were determined.


RESULTS
It was ascertained that recurrence of peptic ulcer was accompanied by essential increasing of calcium and decreasing phosphorus in blood, insignificant hypercalciuria and hyperphosphaturia. These changes were accompanied by considerable increasing of gastric secretional function, decreasing production of gastromucoproteids and gastric hypermotility. The more significant changes of calcium-phosphorus metabolism were determined in the acute phase of the recurrence in duodenal ulcers in young males.


CONCLUSIONS
The evident connection between the impairment of calcium and phosphorus metabolism, the activity of peptic ulcer and changes in the function of stomach can show the importance of these changes in pathogenesis of ulcer and the validity of therapeutic correction of these changes in case of the recurrence.
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Fomina
D000293:Adolescent; D000328:Adult; D002118:Calcium / Q000097:blood*; D005260:Female; D005753:Gastric Mucosa / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000097:blood* / Q000503:physiopathology; D010758:Phosphorus / Q000097:blood*; D012008:Recurrence; D013270:Stomach / Q000503:physiopathology
D010758:Phosphorus; D002118:Calcium