Assessing spatial resolution versus sensitivity from laser speckle contrast imaging: application to frequency analysis.
For blood perfusion monitoring, laser speckle contrast (LSC) imaging is a recent non-contact technique that has the characteristic of delivering noise-like speckled images. To exploit LSC images for quantitative physiological measurements, we developed an approach that implements controlled spatial averaging to reduce the detrimental impact of the noise and improve measurement sensitivity. By this approach, spatial resolution and measurement sensitivity can be traded-off in a flexible way depending on the quantitative prospect of the study. As an application, detectability of the cardiac activity from LSC images of forearm using power spectrum analysis is studied through the construction of spatial activity maps offering a window on the blood flow perfusion and its regional distribution. Comparisons with results obtained with signals of laser Doppler flowmetry probes are performed.
Laboratoire d'Ingénierie des Systèmes Automatisés (LISA), Université d'Angers, Angers, France. sbricq@esaip.org
Stéphanie
S
Bricq
Guillaume
G
Mahé
David
D
Rousseau
Anne
A
Humeau-Heurtier
François
F
Chapeau-Blondeau
Julio Rojas
JR
Varela
Pierre
P
Abraham
D000328:Adult; D005260:Female; D005542:Forearm / Q000098:blood supply; D006801:Humans; D017078:Laser-Doppler Flowmetry; D007834:Lasers; D008297:Male; D008833:Microcirculation / Q000502:physiology; D012039:Regional Blood Flow / Q000502:physiology; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D012867:Skin / Q000098:blood supply*; D055815:Young Adult