Rapid clinical and radiographic improvement after intrathecal trastuzumab and methotrexate in a patient with HER-2 positive leptomeningeal metastases.
Jennifer
J
Martens
Padmaja
P
Venuturumilli
Lindsey
L
Corbets
Daniel
D
Bestul
D000328:Adult; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology / Q000556:secondary; D005260:Female; D006801:Humans; D007278:Injections, Spinal; D008279:Magnetic Resonance Imaging; D055756:Meningeal Carcinomatosis / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary*; D008727:Methotrexate / Q000627:therapeutic use*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism; D000068878:Trastuzumab
D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D008727:Methotrexate; D018719:Erb-b2 Receptor Tyrosine Kinases; D000068878:Trastuzumab; C508053:ERBB2 protein, human