Inter/intra-observer reproducibility of Gleason scoring in prostate adenocarcinoma in Iranian pathologists.
OBJECTIVE
To measure the level of inter/intra-observer reproducibility among pathologists as far as Gleason scoring of adenocarcinoma of the prostate is concerned.


METHODS
A total of 101 prostate biopsy slides, diagnosed with adenocarcinoma of the prostate by five pathologists from different education centers, were exposed to Gleason scoring. Two months later, the slides were re-examined by three of the same pathologists. Thereafter, the kappa was calculated for the data provided in the first and second reports of each pathologist and compared between pathologists.


RESULTS
Inter-observer reproducibility was inappropriate, but intra-observer diagnostic reproducibility was almost perfect with a corresponding percentage of agreement of 85.2%.


CONCLUSIONS
The inter-observer reproducibility was poor.
Department of Pathology, Imam Khomeini Teaching Hospital, Tehran University of Medical Sciences, Tehran, Iran. dr_p_abdollahi@yahoo.com
Alireza
A
Abdollahi
Alipasha
A
Meysamie
Sara
S
Sheikhbahaei
Ali
A
Ahmadi
Hedieh
H
Moradi-Tabriz
Mohammadreza
M
Bakhshandeh
Hassan
H
Hosseinzadeh
D000230:Adenocarcinoma / Q000473:pathology*; D001706:Biopsy; D003430:Cross-Sectional Studies; D006801:Humans; D007492:Iran; D008297:Male; D060787:Neoplasm Grading; D015588:Observer Variation; D011471:Prostatic Neoplasms / Q000473:pathology*; D015203:Reproducibility of Results