Diagnosis of latex allergy: the importance of hev B 11.
We present the cases of 5 patients with a positive clinical history of cutaneous symptoms due to contact with latex products. A latex allergological assessment was made through skin prick tests (SPTs) both with commercial latex extracts and extemporaneous glove extracts, and serum-specific IgE to latex and glove-use tests. In addition, serum-specific IgE to recombinant allergens for Hevea brasiliensis was dosed. Molecular diagnostics in association with the glove-use test and, to a lesser extent, the SPTs with glove eluate are useful diagnostic tests to confirm the diagnosis of latex allergy in patients with mucocutaneous symptoms.
Section of Allergology and Clinical Immunology, Department of Internal Medicine and Infectious Diseases, University of Bari Medical School, Bari, Italy. e.nettis@allergy.uniba.it
E
E
Nettis
E
E
Di Leo
G F
GF
Calogiuri
P
P
Delle Donne
M
M
Di Staso
A
A
Ferrannini
A
A
Vacca
D000328:Adult; D000485:Allergens / Q000276:immunology*; D052179:Antigens, Plant / Q000276:immunology*; D002688:Chitinases / Q000276:immunology*; D003429:Cross Reactions; D005260:Female; D028482:Hevea / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D007840:Latex / Q000276:immunology*; D020315:Latex Hypersensitivity / Q000175:diagnosis* / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D010940:Plant Proteins / Q000276:immunology*; D012882:Skin Tests
D000485:Allergens; D052179:Antigens, Plant; D007840:Latex; D010940:Plant Proteins; D007073:Immunoglobulin E; D002688:Chitinases; C465307:Hev b 11 allergen, Hevea brasiliensis