[Clinical significance of insulin resistance syndrome in development of endothelial dysfunction in patients with primary gout].
Endothelial function has been studied in 175 males with primary gout. It has been established that incidence of endothelial dysfunction in patients with primary gout was associated with the clinical course and was marked most of all in patients who had a chronic gout. The correlations found between the parameters of endothelial dysfunction and impaired carbohydrate metabolism suggest close link and coordination between the above processes which contribute greatly to development and progress of atherosclerosis in such patients.
N N
NN
Kushnarenko
A V
AV
Govorin
O A
OA
Shcherbakova
S G
SG
Sotnikova
O V
OV
Ivanitskaia
D000328:Adult; D050197:Atherosclerosis / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D001786:Blood Glucose / Q000032:analysis; D001916:Brachial Artery / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology; D050260:Carbohydrate Metabolism; D018450:Disease Progression; D004730:Endothelium, Vascular / Q000378:metabolism / Q000503:physiopathology; D006073:Gout / Q000150:complications / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D008875:Middle Aged; D018616:Ultrasonography, Doppler, Duplex / Q000379:methods; D014527:Uric Acid / Q000097:blood; D014664:Vasodilation
D001786:Blood Glucose; D007328:Insulin; D014527:Uric Acid