Docetaxel-induced hand foot syndrome: "No dose is a safe dose".
Docetaxel is an important chemotherapeutic agent used in the management of many solid tumors. The most important side effect of this drug is myelosupression. We report a case of carcinoma breast that developed severe hand-foot syndrome at 75 mg/m(2) doses of docetaxel. The exact mechanism of this side effect in not known. All the physicians using this drug must be aware of this side effect.
Department of Medical Oncology, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry 6, India.
Ankit
A
Jain
Biswajit
B
Dubashi