[Dynamics of folliculogenesis of sexually mature and neonatal ovarian tissue under conditions of long-term heterotopical transplantation].
In this work, a comparative analysis of dynamics of morphological development and endocrine function of transplants of sexually mature and neonatal ovarian tissue was performed under conditions of bilateral ovariectomy of animals-recipients. It has been established that at transplantation of the sexually mature ovarian tissue there were observed all stages of folliculogenesis and preservation of endocrine function at long-term observation (up to 100 days). At transplantation of neonatal ovarian tissue there was revealed a pathological picture of its development: hyperplasia of stromal structure and formation of cysts and cystomae. Follicles of different degree of maturity were revealed in 30 % of animals at the 30th day of observation. A significant increase of concentration of sex hormones as compared with ovariectomied animals has been shown only at early stages after implantation (30 days).
V V
VV
Kiroshka
Iu O
IuO
Tishchenko
D000818:Animals; D004958:Estradiol / Q000097:blood; D005260:Female; D006080:Ovarian Follicle / Q000166:cytology* / Q000254:growth & development*; D010052:Ovariectomy; D010053:Ovary / Q000166:cytology* / Q000637:transplantation*; D011374:Progesterone / Q000097:blood; D051381:Rats; D017208:Rats, Wistar; D016042:Transplantation, Heterotopic
D011374:Progesterone; D004958:Estradiol