N,N-Diarylammonium pyrosulfate as a highly effective reverse micelle-type catalyst for hydrolysis of esters.
Reverse micelle-type N,N-diarylammonium pyrosulfate (3-5 mol %) efficiently catalyzes the hydrolysis of esters (up to 100 mmol scale) under organic solvent-free conditions. The present method is successfully applied to the hydrolysis of various esters without the decomposition of the base-sensitive moieties and without any loss of optical purity for α-heterosubstituted carboxylic acids.
Graduate School of Engineering, Nagoya University, Chikusa, Nagoya, 464-8603, Japan.
Yoshiki
Y
Koshikari
Akira
A
Sakakura
Kazuaki
K
Ishihara