IL-2: fine-tuning the germinal center reaction.
T follicular cells help B cells to drive germinal center formation. In this issue of Immunity, Ballesteros-Tato et al. (2012) demonstrate that high amounts of interleukin-2 inhibit production of this critical T effector subset.
The Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami FL 33136, USA. tmalek@med.miami.edu
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