Ketosis-prone type 2 diabetes mellitus in a patient with Sheehan's syndrome: a rare convergence of two distinct endocrine entities.
A 36-year-old housewife, previously diagnosed with Sheehan's syndrome on glucocorticoid and thyroxine replacement therapy, presented with unprovoked diabetic ketoacidosis. Ketoacidosis was corrected with intravenous fluids and insulin therapy. Further evaluation was suggestive of type 2 diabetes mellitus. On follow-up, she experienced repeated episodes of hypoglycaemia and insulin was tapered and stopped. Adequate glycaemic control was maintained with metformin monotherapy.
Department of Medicine, Kasturba Medical College, Manipal, Karnataka, India.
Kushal
K
Naha
G
G
Vivek
Sowjanya
S
Dasari
Mukhyaprana
M
Prabhu
D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000188:drug therapy; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007018:Hypopituitarism / Q000150:complications* / Q000188:drug therapy; D007328:Insulin / Q000627:therapeutic use; D008687:Metformin / Q000627:therapeutic use; D013974:Thyroxine / Q000627:therapeutic use
D005938:Glucocorticoids; D007004:Hypoglycemic Agents; D007328:Insulin; D008687:Metformin; D013974:Thyroxine