Cardiac disease in a case of precursor B acute lymphoblastic leukaemia with eosinophilia(ALL/Eo).
Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy. However, it may rarely associate with eosinophilia. Patients with ALL associated with eosinophilia (ALL/ Eo) have a grave prognosis and higher incidence of cardiac complications compared to standard lymphoblastic leukaemia. Reports of ALL/Eo disclosed a few case with cardiac involvement early in the course of leukaemia. Here, the authors report a case of 13-year-old boy who presented with peripheral eosinophilia, chest pain and a large left ventricular mass early in the course of precursor B- cell ALL associated with eosinophilia. He received multi-agent chemotherapy but succumbed to death 25 days after chemotherapy due to a refractory cardio respiratory failure.
Department of Medicine, Imam Khomeini Hospital Complex, Tehran, Iran, Islamic Republic of Iran. asadi_m@tums.ac.ir
Mehrnaz Asadi
MA
Gharabaghi
Pegah
P
Aghajanzadeh
Ghazal
G
Zahedi
Roghayyeh
R
Borji
Leila
L
Derakhskan
Roya
R
Sattarzadeh
Ramezanali
R
Sharaifian
D000293:Adolescent; D004452:Echocardiography; D004802:Eosinophilia / Q000150:complications* / Q000473:pathology; D017809:Fatal Outcome; D006331:Heart Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000473:pathology