Factor X deficiency: an uncommon presentation of AL amyloidosis.
Factor X deficiency is the most common coagulation factor deficiency amongst patients with AL amyloidosis. It presumably occurs due to adsorption of factor X to amyloid fibrils. The deficiency of this factor, in conjunction with other hemostatic defects, can cause bleeding complications. A case of acquired factor X deficiency due to AL amyloidosis is reported, where abnormal coagulation parameters were the only presenting feature.
Emory University Hospital, 1364 Clifton Road NE, Atlanta, GA 30322, USA. ajaydastm@yahoo.co.in
Ajaydas T
AT
Manikkan
D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis*; D005171:Factor X Deficiency / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male