[Long-term outcomes and nutrition evaluation in children with total colonic aganglionosis].
OBJECTIVE
To examine the long-term outcomes of total colonic aganglionosis (TCA) and to evaluate their nutritional status.


METHODS
Eleven pediatric patients treated for TCA between January 1999 and December 2010 were included in the study and followed up. Physical measurements including height, weight and laboratory tests were assessed. Anorectal functions were evaluated with Kelly score and quality of life(QOL) using questionnaire.


RESULTS
The length of follow-up ranged from 8 to 147 months. The children had satisfactory anorectal function (Kelly score, 5-6). One child had a Kelly score of 3. The children who were followed up less than 48 months had significant higher Kelly scores compared with those with more than 48 months follow-up(P<0.05). QOL was good in nine patients (QOL score, 9-10) and moderate (score, 7-8) in 2 patients. Weight-for-age was normal in 2 patients, mild malnutrition in 6 patients, and moderate malnutrition in 3 patients. Height-for-age was normal in 6 patients, mild malnutrition in 3 patients, and moderate malnutrition in 2 patients. The serum albumin was(49.0±2.7) g/L in children with well-educated parents, significantly higher than those with poorly-educated parents(44.3±1.9) g/L(P<0.05).


CONCLUSIONS
Long-term outcomes of children with TCA are satisfactory with good anorectal function and quality of life. Low body weight is more common than low height.  Children with well-educated parents have better nutrition status.
Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou, China.
Wei
W
Zhong
Jia-kang
JK
Yu
Hui-min
HM
Xia
Jing
J
Sun
Rui-qiong
RQ
Li
Yi-min
YM
Nong
Yong
Y
Wang
Le
L
Li
D005500:Follow-Up Studies; D006627:Hirschsprung Disease / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D009752:Nutritional Status; D016896:Treatment Outcome