[The application of botulinum toxin in oromandibular, pharyngeal and laryngeal dystonia].
Dystonias of the oral, pharyngeal and laryngeal muscles are potential causes of deglutitive, respiratory and communicative disorders. In addition to functional deficits such as dysphagia, dysarthria and dysphonia, social disadvantages may arise from the visible or audible manifestations. Treatment with botulinum toxin offers symptomatic and temporary therapeutic effects. Examples of applications in oromandibular dystonia, palatoclonus, dysphagia and laryngeal dystonia (e.g., spasmodic dysphonia) are described.
Phoniatrie und Pädaudiologie, Klinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsmedizin Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Deutschland. olthoff@med.uni-goettingen.de
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Olthoff
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Laskawi
D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D004421:Dystonia / Q000188:drug therapy*; D006801:Humans; D007818:Laryngeal Diseases / Q000188:drug therapy*; D008336:Mandibular Diseases / Q000188:drug therapy*; D009059:Mouth Diseases / Q000188:drug therapy*; D009465:Neuromuscular Agents / Q000627:therapeutic use; D010608:Pharyngeal Diseases / Q000188:drug therapy*
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A