One-step continuous synthesis of biocompatible gold nanorods for optical coherence tomography.
We present a novel one-step flow process to synthesize biocompatible gold nanorods with tunable absorption and biocompatible surface ligands. Photothermal optical coherence tomography (OCT) of human breast tissue is successfully demonstrated using tailored gold nanorods designed to have strong absorption in the near-infrared range.
Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
Víctor
V
Sebastián
Seung-Kon
SK
Lee
Chao
C
Zhou
Martin F
MF
Kraus
James G
JG
Fujimoto
Klavs F
KF
Jensen
D001940:Breast / Q000648:ultrastructure; D003287:Contrast Media / Q000737:chemistry; D005260:Female; D006046:Gold / Q000737:chemistry*; D006801:Humans; D008024:Ligands; D043942:Nanotubes / Q000737:chemistry*; D013499:Surface Properties; D041623:Tomography, Optical Coherence
D003287:Contrast Media; D008024:Ligands; D006046:Gold