Triple negative mixed metaplastic breast carcinoma with squamous and spindle cells in an 84-year-old woman: a rare entity with unclear management strategy and poor prognosis.
Metaplastic carcinoma of the breast, a rare neoplasm, usually presents at an advanced stage, metastasises to distant sites more frequently, has higher Ki-67 expression and is more often triple negative compared with other invasive breast cancers. Here, the authors discuss a case of an 84-year-old woman with triple negative mixed metaplastic breast carcinoma treated with radical modified mastectomy, axillary lymph node dissection and radiation therapy. Because of the rarity of the disease, the pathogenesis and the management remain controversial, thus contributing to overall poor prognosis.
Department Of Medicine, Staten Island University Hospital, Staten Island, New York, USA. srujitha.murukutla@gmail.com
Srujitha
S
Murukutla
Vijaya Raj
VR
Bhatt
Abhirami
A
Vivekanandarajah
Cynara
C
Coomer
Shilpi
S
Gupta
D000369:Aged, 80 and over; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015411:Mastectomy, Modified Radical; D018193:Neoplasms, Complex and Mixed / Q000175:diagnosis* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D011379:Prognosis