Protein expression, aggregation, and triggered release from polymersomes as artificial cell-like structures.
Bringing droplets to life: A cytoskeletal protein (red dots, see scheme) is expressed in artificial cells composed of biocompatible polymersomes, which encapsulate expression machinery and amino acid building blocks. Release of the expressed proteins can be triggered by a negative osmotic shock.
The Division of Biomedical Engineering, School of Engineering, The University of Glasgow, Glasgow, G12 8LT, UK.
Chiara
C
Martino
Shin-Hyun
SH
Kim
Louise
L
Horsfall
Alireza
A
Abbaspourrad
Susan J
SJ
Rosser
Jonathan
J
Cooper
David A
DA
Weitz
D058045:Artificial Cells / Q000737:chemistry; D009821:Oils / Q000737:chemistry; D009997:Osmotic Pressure; D011506:Proteins / Q000737:chemistry*; D014867:Water / Q000737:chemistry
D009821:Oils; D011506:Proteins; D014867:Water