Allenylphosphonates/allenylphosphine oxides as intermediates/precursors for intramolecular cyclization leading to phosphorus-based indenes, indenones, benzofurans, and isochromenes.
Utilizing internally available functional groups, a simple protocol for the efficient synthesis of phosphorus-based indenes, indenones, benzofurans, and isochromenes via intramolecular cyclization of allene intermediates/precursors is generated; the latter intermediates/precursors are conveniently obtained through aldehyde-, alkylidene-, and hydroxyl-functionalized propargyl alcohols and P(III)-Cl precursors. The structures of key products have been unequivocally confirmed by X-ray crystallography.
School of Chemistry, University of Hyderabad, Hyderabad 500 046, A. P., India.
K V
KV
Sajna
K C
KC
Kumara Swamy
D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry*; D001578:Benzopyrans / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007192:Indenes / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D013237:Stereoisomerism
D001572:Benzofurans; D001578:Benzopyrans; D007192:Indenes; D009943:Organophosphorus Compounds; D010720:Phosphines