Preserving the right to future children: an ethical case analysis.
We report on the case of a 2-year-old female, the youngest person ever to undergo ovarian tissue cryopreservation (OTC). This patient was diagnosed with a rare form of sickle cell disease, which required a bone-marrow transplant, and late effects included high risk of future infertility or complete sterility. Ethical concerns are raised, as the patient's mother made the decision for OTC on the patient's behalf with the intention that this would secure the option of biological childbearing in the future. Based on Beauchamp and Childress's principlism approach of respect for autonomy, nonmaleficence, beneficence, and justice, pursing OTC was ethically justified.
Moffitt Cancer Center, Health Outcomes and Behavior Program, Tampa, FL 33612, USA. gwen.quinn@moffitt.org
Gwendolyn P
GP
Quinn
Daniel K
DK
Stearsman
Lisa
L
Campo-Engelstein
Devin
D
Murphy
D000755:Anemia, Sickle Cell / Q000601:surgery; D026686:Beneficence; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D002675:Child, Preschool; D015925:Cryopreservation / Q000941:ethics; D003657:Decision Making / Q000941:ethics*; D026689:Ethical Analysis; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000517:prevention & control*; D009035:Mothers; D009679:Nuclear Family; D010053:Ovary; D026684:Personal Autonomy; D028662:Principle-Based Ethics; D046269:Reproductive Rights / Q000941:ethics*; D012935:Social Justice