Predictors of screening for AIDS clinical trials among African-Americans and Latino/Hispanics enrolled in an efficacious peer-driven intervention: uncovering socio-demographic, health, and substance use-related factors that promote or impede screening.
African-American and Latino/Hispanic persons living with HIV/AIDS are underrepresented in AIDS clinical trials (ACTs). The aim of this paper was to uncover factors, either unmodifiable or not directly targeted for change, that predicted screening for ACTs during an efficacious peer-driven intervention (N = 540 total; N = 351 in an intervention arm, N = 189 control). This paper focused on participants assigned to an intervention arm, 56 % of whom were screened for ACTs. We found a decreased odds of screening was associated with closer proximity to the screening site, gay/lesbian orientation, lower mental health symptoms, current injection drug use, more recent HIV diagnosis, lack of prior screening experience, and failure to attend all intervention sessions, but there were no gender or racial/ethnic differences. Efforts to reduce racial/ethnic disparities in ACTs can be enhanced by attending to these specific factors, which may interfere with programmatic efforts to increase African-American and Latino/Hispanic representation in ACTs.
Center for Drug Use and HIV Research, New York University College of Nursing, NY 10003, USA. mg2890@nyu.edu
Marya
M
Gwadz
Charles M
CM
Cleland
Noelle R
NR
Leonard
Amanda S
AS
Ritchie
Angela
A
Banfield
Marion
M
Riedel
Pablo
P
Colon
Donna
D
Mildvan
D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000208:ethnology; D000328:Adult; D001741:Black or African American / Q000706:statistics & numerical data*; D004522:Educational Status; D005260:Female; D015438:Health Behavior / Q000208:ethnology; D057220:Health Literacy; D054624:Health Status Disparities; D006630:Hispanic or Latino / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000706:statistics & numerical data*; D008603:Mental Health; D008875:Middle Aged; D010379:Peer Group; D011237:Predictive Value of Tests; D016032:Randomized Controlled Trials as Topic; D019966:Substance-Related Disorders / Q000453:epidemiology* / Q000208:ethnology; D014481:United States / Q000453:epidemiology / Q000208:ethnology; D035862:Vulnerable Populations