Modern management of acute myocardial infarction.
Disruption of intracoronary plaque with thrombus formation provides the pathophysiologic foundation for acute coronary syndromes, which comprise ST-segment myocardial infarction, non-ST-segment myocardial infarction, and unstable angina. Management differs depending on whether ST-segment elevation is present, but the general principles of timely restoration of coronary blood flow and initiation of secondary prevention strategies are applicable to all patients. The purpose of this review is to discuss first the epidemiology, pathophysiology, and diagnosis of acute myocardial infarction. Risk stratification and therapy for patients with ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndromes are then reviewed along with diagnosis and management of the complications of myocardial infarction.
Terrence D
TD
Welch
Eric H
EH
Yang
Guy S
GS
Reeder
Bernard J
BJ
Gersh
D015415:Biomarkers / Q000097:blood; D002317:Cardiovascular Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004562:Electrocardiography / Q000379:methods; D006801:Humans; D009203:Myocardial Infarction / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D015425:Myocardial Reperfusion / Q000379:methods; D018570:Risk Assessment / Q000379:methods
D015415:Biomarkers; D002317:Cardiovascular Agents