Childhood leukemia and its impact on graduation and having children: results from a national survey.
To assess the level of graduation, the wish to have children and the course of pregnancy among former patients with childhood leukemia in comparison to the general German population and depending on gender, a nationwide survey was conducted in 2008. In total 63.6% (1476/2319) of the contacted survivors of childhood leukemia participated (mean age 25.7 years, range 19-43 years). Survivors graduated at higher levels of school compared to the general population, with 48.6% (female) versus 38.0% and 52.6% (male) versus 35.8% (p < 0.001). Also, 93.3% of female and 89.3% of male survivors indicated a similar general wish to have children compared to the general population. Survivors reported parenthood less frequently compared to the general population (p < 0.001). The course of pregnancy in survivors was characterized by fewer abortions (p < 0.001). Having leukemia in childhood and adolescence impairs the likelihood of becoming a parent but reduces neither the wish to have children nor the level of graduation.
Department of Pediatric Oncology/Hematology/Stem Cell Transplantation, Charité University Medical Center Berlin, Germany.
Anne
A
Zynda
Simone
S
Reinmuth
Constanze
C
Pfitzer
Cynthia
C
Hohmann
Thomas
T
Keil
Anja
A
Borgmann-Staudt
D000124:Achievement; D000293:Adolescent; D000328:Adult; D059248:Chemoradiotherapy; D002648:Child; D004522:Educational Status; D005260:Female; D005858:Germany; D006040:Goals; D006801:Humans; D007938:Leukemia / Q000523:psychology* / Q000628:therapy; D008297:Male; D016487:Parenting / Q000523:psychology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011795:Surveys and Questionnaires; D017741:Survivors / Q000706:statistics & numerical data; D055815:Young Adult