p-tert-Butylphenol formaldehyde resin and its impact on children.
: p-tert-Butylphenol formaldehyde resin (PTBPFR) is widely used as an adhesive owing to its rapid onset of action, durability, flexibility, and heat resistance. Moreover, because of its tackiness, it is particularly useful as a glue component on both leather and rubber products. Sensitization to this resin has been increasing since the first cases of PTBPFR contact allergy in the late 1950s, and pediatric contact allergy to this resin is a significant problem. p-tert-Butylphenol formaldehyde resin has been reported as a leading cause of shoe-associated dermatitis internationally, as well as a cause of allergic contact dermatitis from its use in neoprene wet suits and sports equipment such as shin guards. In summary, patch test screening of both adults and children with PTBPFR is important, given the ubiquitous use of this chemical.
Division of Pediatric and Adolescent Dermatology, University of California, San Diego-Rady Children's Hospital, San Diego, CA, USA.
Elise
E
Herro
Sharon E
SE
Jacob
D000269:Adhesives / Q000009:adverse effects*; D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000009:adverse effects / Q000276:immunology; D002648:Child; D017449:Dermatitis, Allergic Contact / Q000209:etiology* / Q000276:immunology; D006801:Humans; D007509:Irritants / Q000009:adverse effects*; D010328:Patch Tests / Q000379:methods; D012117:Resins, Synthetic / Q000009:adverse effects* / Q000737:chemistry; D012775:Shoes / Q000009:adverse effects; D019876:Sports Equipment / Q000009:adverse effects
D000269:Adhesives; D000485:Allergens; D007509:Irritants; D012117:Resins, Synthetic; C014273:p-tert-butylphenolformaldehyde resin