Simultaneous swept source optical coherence tomography of the anterior segment and retina using coherence revival.
We report on an implementation of coherence revival-based heterodyne swept source optical coherence tomography that is capable of simultaneously imaging the anterior and posterior eye. A polarization-encoded sample arm was used to efficiently focus orthogonal polarizations on the anterior segment and retina. Depth encoding was achieved using coherence revival, which allows for multiple depths within a sample to be simultaneously imaged and frequency encoded by carefully controlling the optical pathlength of each sample path. This design is a significant step toward whole-eye optical coherence tomography (OCT), which would enable customized ray-traced modeling of patient eyes to improve refractive surgical interventions and eliminate optical artifacts in retinal OCT diagnostics. We demonstrated the feasibility of this system for in vivo imaging by simultaneously acquiring images of the anterior segments and retinas in healthy human volunteers.
Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708, USA. al.dhalla@duke.edu
Al-Hafeez
AH
Dhalla
Derek
D
Nankivil
Theresa
T
Bustamante
Anthony
A
Kuo
Joseph A
JA
Izatt
D000869:Anterior Eye Segment / Q000166:cytology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D012160:Retina / Q000166:cytology*; D013997:Time Factors; D041623:Tomography, Optical Coherence / Q000379:methods*