[A modern viewpoint on structure and evolution of collagens. I. Fibrillar collagens].
This review summarizes current data on structure of the most representative group of the collagen family--fibrillar collagens. Attention has been focused on structural organization of individual domains and their functional role in the hierarchical stacking of alpha-chains of collagens. There is presented characteristics of the main stages of biosynthesis and of supramolecular processing of fibrillar collagens. Also considered are some aspects of evolution of fibrillar collagens. The role of duplication of genome and genes, intergene rearrangements, and exon shuffling in evolution of collagen genes is discussed.
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VP
Ivanova
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Krivchenko
D000818:Animals; D019143:Evolution, Molecular; D005109:Extracellular Matrix / Q000235:genetics; D024022:Fibrillar Collagens / Q000737:chemistry* / Q000145:classification / Q000235:genetics*; D020440:Gene Duplication; D016678:Genome; D006801:Humans; D055503:Protein Multimerization; D017434:Protein Structure, Tertiary; D013329:Structure-Activity Relationship
D024022:Fibrillar Collagens