Anterocollis and camptocormia in parkinsonism: a current assessment.
Postural deformities in parkinsonian syndromes are well recognized, but poorly understood and largely refractory to available therapies. In recent times a number of hypotheses have been proposed to explain the underlying etiology of anterocollis and camptocormia, but currently there is no consensus. As these conditions are more precisely characterized we begin to uncover that this is a heterogeneous and evolving phenomenon. These conditions bring to light the inadequacies of our current tools to study biomechanics of posture, neuromuscular disorders, and dystonic muscular contractions. The development of objective, accurate tools to directly study and measure the severity of these postural disorders will allow for further understanding of the pathophysiology, the development of novel therapeutics, and adequate clinical trial design.
Department of Neurosciences, Movement Disorder Program, Medical University of South Carolina, 326 Calhoun Street, Suite 308/MSC 108, Charleston, SC 29425, USA. revuelta@musc.edu
Gonzalo J
GJ
Revuelta
D004421:Dystonia / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D009134:Muscular Atrophy, Spinal / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D009135:Muscular Diseases / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D020734:Parkinsonian Disorders / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D011187:Posture / Q000502:physiology; D013121:Spinal Curvatures / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D014103:Torticollis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy