Biologically meaningful coverage indicators for eliminating malaria transmission.
Mosquitoes, which evade contact with long-lasting insecticidal nets and indoor residual sprays, by feeding outdoors or upon animals, are primary malaria vectors in many tropical countries. They can also dominate residual transmission where high coverage of these front-line vector control measures is achieved. Complementary strategies, which extend insecticide coverage beyond houses and humans, are required to eliminate malaria transmission in most settings. The overwhelming diversity of the world's malaria transmission systems and optimal strategies for controlling them can be simply conceptualized and mapped across two-dimensional scenario space defined by the proportion of blood meals that vectors obtain from humans and the proportion of human exposure to them which occurs indoors.
Biomedical and Environmental Thematic Group, Ifakara Health Institute, PO Box 53, Ifakara, Tanzania.
Samson S
SS
Kiware
Nakul
N
Chitnis
Gregor J
GJ
Devine
Sarah J
SJ
Moore
Silas
S
Majambere
Gerry F
GF
Killeen
D000818:Animals; D000852:Anopheles; D003140:Communicable Disease Control / Q000379:methods; D009033:Culicidae; D005247:Feeding Behavior; D006801:Humans; D007306:Insecticides / Q000494:pharmacology; D008288:Malaria / Q000517:prevention & control* / Q000635:transmission*; D015233:Models, Statistical; D008962:Models, Theoretical; D009032:Mosquito Control / Q000379:methods; D011157:Population Dynamics; D013045:Species Specificity
D007306:Insecticides