Penetration resistance: PKR's other talent.
In this issue of Immunity, Irving et al. (2012) show that protein kinase R (PKR) regulates the cytoskeleton via an interaction with gelsolin. This alternative role for PKR prevents penetration of virions into the cell.
Developmental Immunology/CCIB Massachusetts General Hospital/Harvard Medical School, Boston, MA 02144, USA.
Adam
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Lacy-Hulbert
Lynda M
LM
Stuart