Analysis of 49 autosomal SNPs in an Iraqi population.
Forty-nine of the 52 autosomal single nucleotide polymorphisms (SNPs) in the SNPforID 52plex were typed in 101 unrelated Iraqis living in Denmark. No significant deviation from HWE was found in all but one of the 49 SNP systems and no significant pairwise linkage disequilibrium was observed for any SNP pair. When 18 worldwide populations were compared (including populations in Iraq, Turkey, Israel, Pakistan, India, China, Taiwan, Japan, Siberia, Algeria, Somalia, Uganda, Mozambique, Angola, Nigeria, Denmark, Portugal, Spain), a significant global F(ST) value was obtained. All but six F(ST) values were statistically significant when pairwise comparisons were performed between the 18 populations. The Iraqi population did not show significant difference from the population in Turkey and it grouped together with other Middle-Eastern populations when a multidimensional scaling plot was drawn based on the pairwise F(ST) values. The combined mean match probability and the typical paternity index for trios were 8.3×10(-20) and 259,000, respectively, for the Iraqi population.
Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health Sciences, University of Copenhagen, Frederik V's Vej 11, DK-2100 Copenhagen, Denmark.
Carmen
C
Tomas
Isabel E
IE
Diez
Enrique
E
Moncada
Claus
C
Børsting
Niels
N
Morling
D005828:Genetics, Population; D006801:Humans; D007493:Iraq; D020641:Polymorphism, Single Nucleotide; D011786:Quality Control