Application of high frequency bipolar electrocoagulation LigaSure™ in appendix vermiformis of rabbits with or without acute inflammatory process.
OBJECTIVE
To evaluate the efficacy of the use of LigaSure™ in appendectomy, with or without acute inflammatory process, and to compare with simple ligature and conventional therapy.


METHODS
A total of 30 rabbits (Oryctolagus cuniculus) randomly allocated in two groups, group A and B, of 15 animals each were used. The group A without acute appendicitis and the group B with acute appendicitis were submitted to appendectomy. After, the groups were subdivided into three groups, each group containing five rabbits submitted to simple ligature, conventional therapy and application of LigaSure™. We assessed macroscopic and microscopy parameters of appendiceal stump and operative wound.


RESULTS
The group with acute appendicitis that LigaSure™ was applied had fibrosis in 100% of animals, as well as in the other operative techniques used. It suggested that application of LigaSure™ is efficient as other techniques used in healing of appendiceal stump.


CONCLUSIONS
The application of LigaSure™ induces the formation of fibrosis in the appendiceal stump. The technique proved efficacy to induce enough fibrous tissue to obstruct leakage of enteric content.
Medical School, UNICID, Sao Paulo-SP, Brazil.
Laura Cristina de
LC
Souza
Maíra Rocha
MR
Ortega
Eduardo
E
Achar
Dante
D
Simionato Netto
Marcelo Augusto Fontenelle
MA
Ribeiro Junior
D000208:Acute Disease; D000818:Animals; D001062:Appendectomy / Q000379:methods* / Q000592:standards; D001064:Appendicitis / Q000473:pathology / Q000601:surgery*; D004195:Disease Models, Animal; D004564:Electrocoagulation / Q000379:methods* / Q000592:standards; D005260:Female; D010535:Laparoscopy / Q000379:methods; D008026:Ligation; D008297:Male; D011817:Rabbits; D011897:Random Allocation; D013536:Suture Techniques