A biochemically semi-detailed model of auxin-mediated vein formation in plant leaves.
We present here a model intended to capture the biochemistry of vein formation in plant leaves. The model consists of three modules. Two of these modules, those describing auxin signaling and transport in plant cells, are biochemically detailed. We couple these modules to a simple model for PIN (auxin efflux carrier) protein localization based on an extracellular auxin sensor. We study the single-cell responses of this combined model in order to verify proper functioning of the modeled biochemical network. We then assemble a multicellular model from the single-cell building blocks. We find that the model can, under some conditions, generate files of polarized cells, but not true veins.
Department of Chemistry and Biochemistry, University Hall, University of Lethbridge, Lethbridge, Alberta T1K 3M4, Canada. roussel@uleth.ca
Marc R
MR
Roussel
Martin J
MJ
Slingerland
D003198:Computer Simulation; D007210:Indoleacetic Acids / Q000378:metabolism*; D026901:Membrane Transport Proteins / Q000378:metabolism*; D008954:Models, Biological; D063245:Plant Development / Q000502:physiology*; D018515:Plant Leaves / Q000033:anatomy & histology / Q000254:growth & development*; D010940:Plant Proteins / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology*
D007210:Indoleacetic Acids; D026901:Membrane Transport Proteins; D010940:Plant Proteins