Pulmonary extramedullary haematopoiesis.
A 72-year-old Caucasian lady with myeloproliferative disorder was admitted for evaluation of progressive dyspnoea, weight loss, fatigue and mild hypoxia. A diffuse ground glass opacity was seen on CT pulmonary angiogram. Differential diagnoses included heart failure, infection, progression of myeloproliferative disorder with extramedullary haematopoiesis, thromboembolism or hydroxyurea-induced lung injury. Bronchoscopy and broncho-alveolar lavage were uninformative however lung biopsy with video-assisted thoracoscopy revealed extramedullary haematopoiesis within lung parenchyma. This is a very rare complication of myeloproliferative disorder and the authors discuss the significance of the case, review the literature and report the patient's progress.
Thoracic Medicine Department, Mater Public Hospital, Brisbane, Queensland, Australia. veenumubarak@yahoo.com
Veenu
V
Mubarak
Stephen
S
Fanning
Morgon
M
Windsor
Edwina
E
Duhig
Simon
S
Bowler
D000368:Aged; D005260:Female; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D008168:Lung / Q000473:pathology / Q000502:physiology*