The future of tissue-engineered organs for transplant? It's here!
The first-in-man bioengineered artificial tracheobronchial transplant consisting of a synthetic scaffold and autologous bone marrow-derived mesenchymal cells was recently reported. Extensive evaluation of the patient before and after transplant provides some insight into the potential mechanisms of stem cell mobilization and tracheal tissue regeneration.
Division of Blood and Marrow Transplantation, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455, USA. panos001@umn.edu
Angela
A
Panoskaltsis-Mortari
D005544:Forecasting; D006801:Humans; D033581:Stem Cell Transplantation / Q000639:trends; D023822:Tissue Engineering / Q000639:trends*; D054457:Tissue Scaffolds / Q000639:trends; D014132:Trachea / Q000637:transplantation; D014182:Transplantation, Autologous / Q000639:trends; D019737:Transplants / Q000639:trends*