Cushing's disease presenting with pituitary apoplexy.
Pituitary tumour apoplexy is a rare but life threatening condition. Cushing's disease usually presents with clinical features of Cushing's syndrome. We report a 30-year-old male patient with Cushing's disease who presented with severe headache and right third nerve palsy. MRI of the pituitary gland revealed a pituitary adenoma with infarction suggestive of apoplexy. After a transsphenoidal surgery he developed pan-hypopituitarism with diabetes insipidus. We also review the relevant literature.
Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Daniel
D
Chan
Teo Cheng
TC
Rong
Rinkoo
R
Dalan
D000328:Adult; D003919:Diabetes Insipidus / Q000503:physiopathology; D006261:Headache / Q000209:etiology; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination; D019635:Neurosurgical Procedures; D056128:Obesity, Abdominal / Q000150:complications; D015840:Oculomotor Nerve Diseases / Q000150:complications; D047748:Pituitary ACTH Hypersecretion / Q000473:pathology* / Q000601:surgery; D010899:Pituitary Apoplexy / Q000473:pathology* / Q000601:surgery; D010902:Pituitary Gland / Q000473:pathology; D010907:Pituitary Hormones / Q000097:blood; D011183:Postoperative Complications / Q000503:physiopathology; D014057:Tomography, X-Ray Computed
D010907:Pituitary Hormones