Hyperleukocytosis in a premature infant with intrauterine herpes simplex encephalitis.
Herpes encephalitis is a rare but devastating infection in premature infants. We report a 29 week gestation infant with severe intrauterine cutaneous and central nervous system herpes accompanied by hyperleukocytosis. Leukemoid reactions are not uncommon in this population, but the association of herpes encephalitis and a leukemoid reaction or hyperleukocytosis has not been reported previously.
Department of Pediatrics, University of California, Davis School of Medicine, Sacramento, CA 95817, USA. mark.underwood@ucdmc.ucdavis.edu
M A
MA
Underwood
A E
AE
Wartell
R A
RA
Borghese
D000328:Adult; D020803:Encephalitis, Herpes Simplex / Q000150:complications* / Q000175:diagnosis; D017809:Fatal Outcome; D005260:Female; D005315:Fetal Diseases; D006558:Herpes Genitalis / Q000175:diagnosis / Q000635:transmission; D006561:Herpes Simplex / Q000150:complications*; D018258:Herpesvirus 2, Human / Q000302:isolation & purification*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases; D007955:Leukemoid Reaction / Q000209:etiology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis