Bis(oxazoline)-based coordination polymers: a recoverable system for enantioselective Henry reactions.
An efficient release-capture strategy for the recovery and reuse of enantioselective catalysts in the Henry reaction is described. This strategy is based on the precipitation of an insoluble coordination polymer at the end of each reaction, allowing easy separation from products. The coordination polymer is formed through aggregation of Cu(II) ions with ditopic bisoxazoline-based chiral ligands. Up to 11 catalytic cycles have been conducted keeping good yields and enantioselectivities.
Instituto de Síntesis Química y Catálisis Homogénea (ISQCH) and Instituto Universitario de Catálisis Homogénea (IUCH), CSIC - Universidad de Zaragoza, E-50009 Zaragoza, Spain.
Beatriz
B
Angulo
José I
JI
García
Clara I
CI
Herrerías
José A
JA
Mayoral
Ana C
AC
Miñana
D000447:Aldehydes / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D008024:Ligands; D015394:Molecular Structure; D009574:Nitro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010080:Oxazoles / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
D000447:Aldehydes; D008024:Ligands; D009574:Nitro Compounds; D009942:Organometallic Compounds; D010080:Oxazoles; D011108:Polymers; D003300:Copper