[Analysis of titration curves of serum antibodies obtained by ELISA].
Different forms of titration curves obtained by ELISA for serum antibodies, monoclonal antibodies and polyreactive immunoglobulins were considered. A new interpretation of dose-dependent titration curves was suggested. It was shown that our interpretation of dose-dependent titration curves for antibodies which are presented in some biological liquids allow obtaining additional information about properties of the samples. This information was not obtained earlier because of the wrong understanding of the considered problem.
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Bobrovnik
D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis*; D000915:Antibody Affinity; D000918:Antibody Specificity; D000937:Antigen-Antibody Reactions / Q000276:immunology; D003627:Data Interpretation, Statistical; D004797:Enzyme-Linked Immunosorbent Assay / Q000592:standards / Q000706:statistics & numerical data*; D006801:Humans; D007136:Immunoglobulins; D044967:Serum / Q000737:chemistry* / Q000276:immunology
D000911:Antibodies, Monoclonal; D007136:Immunoglobulins