Neuropsychiatric complications of aging with HIV.
Persons over age 50 are not only aging with human immunodeficiency virus (HIV) infection but also represent a high proportion of new HIV infections. Neuropsychiatric symptoms, including depression, cognitive impairment, and substance abuse, are very common in individuals infected with HIV. However, there is little understanding of the relationship between these HIV-related comorbid conditions in newly infected elderly patients compared to uninfected elderly and those who have survived after 20 years of HIV/AIDS. We summarize the current theories and research that link aging and HIV with psychiatric illnesses and identify emerging areas for improved research, treatment, and patient care.
Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. cwatkins@jhmi.edu
Crystal C
CC
Watkins
Glenn J
GJ
Treisman
D015526:AIDS Dementia Complex / Q000188:drug therapy / Q000453:epidemiology / Q000523:psychology*; D000375:Aging / Q000523:psychology*; D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D003072:Cognition Disorders / Q000188:drug therapy / Q000453:epidemiology / Q000523:psychology*; D015897:Comorbidity; D006801:Humans; D008017:Life Expectancy; D015995:Prevalence; D011618:Psychotic Disorders / Q000188:drug therapy / Q000453:epidemiology / Q000523:psychology*; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000188:drug therapy / Q000453:epidemiology / Q000523:psychology*; D014481:United States / Q000453:epidemiology
D019380:Anti-HIV Agents