Chitosan-based heterogeneous catalysts for enantioselective Michael reaction.
Novel chitosan-supported cinchona alkaloids have been developed as heterogeneous catalysts for enantioselective Michael reaction. As-synthesized products as organocatalysts for asymmetric Michael reaction have a high efficiency, providing highly functionalized products (containing adjacent quaternary and tertiary stereocenters) with good stereoselectivity (up to 93% enantiomeric excess) in high yields and recyclability (up to five runs).
College of Chemistry and Chemical Engineering, Henan University, Kaifeng, China.
Yanyan
Y
Qin
Wenshan
W
Zhao
Lili
L
Yang
Xuan
X
Zhang
Yuanchen
Y
Cui