Rapid acute onset of bronchiolitis obliterans syndrome in a lung transplant recipient after respiratory syncytial virus infection.
Bronchiolitis obliterans syndrome (BOS) can have either an acute or chronic onset with an abrupt or insidious course. The diagnosis is typically achieved by physiological criteria with development of a sustained decline in expiratory flow rates for at least 3 weeks. We review the rapid development of acute BOS and bronchiectasis after respiratory syncytial virus infection in a lung transplant recipient, who had been doing well with normal pulmonary function for 3 years after lung transplantation.
The Ohio State University, Columbus, Ohio 43205, USA. don.hayes@nationwidechildrens.org
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D
Hayes
H M
HM
Mansour
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S
Kirkby
A B
AB
Phillips
D000208:Acute Disease; D001987:Bronchiectasis; D001989:Bronchiolitis Obliterans / Q000175:diagnosis* / Q000503:physiopathology; D003550:Cystic Fibrosis / Q000150:complications; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D016040:Lung Transplantation / Q000009:adverse effects*; D018357:Respiratory Syncytial Virus Infections / Q000150:complications* / Q000821:virology; D012136:Respiratory Syncytial Viruses; D013577:Syndrome; D013997:Time Factors; D055815:Young Adult