Non heart beating organ donor: new experimental model in pigs.
OBJECTIVE
To describe technical aspects of a new experimental model that simulates a non heart beating organ donor.


METHODS
Landrace pigs were operated on and cardiac arrest was obtained by means of myocardial infarction and interruption of ventilator support.


RESULTS
Mean cardiac frequency, systolic and diastolic blood pressure levels, central venous pressure, oxygen saturation and concentration of expired CO(2) dropout occurred at seven minutes after cardiac arrest.


CONCLUSIONS
The procedure was easily reproduced and a homogeneous circulatory failure could de obtained by the end of seven minutes. The model is suitable for further studies regarding abdominal organ transplantation.
Program in Health Sciences, UFG, Goiania-GO, Brazil.
Lúcio Kenny
LK
Morais
Pedro Moraes da
PM
Silva Júnior
Juan Carlos Duke
JC
Moreno
Andressa Machado Santana
AM
Brasil
João Paulo Figueiredo
JP
Camarço
Sarah Barboza
SB
Martins
Claudemiro
C
Quireze Júnior
D000818:Animals; D002245:Carbon Dioxide / Q000378:metabolism; D006085:Graft Survival; D006323:Heart Arrest / Q000503:physiopathology; D008297:Male; D023421:Models, Animal; D009926:Organ Preservation; D010100:Oxygen / Q000378:metabolism; D013552:Swine; D014019:Tissue Donors; D014180:Transplantation / Q000379:methods
D002245:Carbon Dioxide; D010100:Oxygen