Bioelectrical impedance analysis in the assessment of hydration status in peritoneal dialysis patients.
OBJECTIVE
Assessment of fluid status in chronic peritoneal dialysis (PD) patients is complex. Clinical evaluation based solely on body weight, blood pressure, volume of ultrafiltration (UF) and peripheral edema is insufficient. A non-invasive test, bioelectrical impedance analysis (BIA) might be of potential benefit.


OBJECTIVE
To test whether BIA correlates with other ancillary markers of extracellular fluid volume, namely B-type natriuretic peptide (BNP), residual renal function (RRF) and UF, and whether BIA provides complementary information in categorizing PD patients vis-à-vis hydration status.


METHODS
A cross-sectional study of 61 out-patients on chronic PD. Single-frequency BIA measurements of resistance/height were divided into tertiles (lowest: <253 Ω/m; middle: >253 Ω/m and <316 Ω/m; highest: >316 Ω/m).


RESULTS
Compared to patients in the highest tertile of BIA (least fluid), patients in the lowest tertile (most fluid) had highest BNP, RRF and UF (93.5 vs. 55.0 pg/ml, p = 0.029; 850 vs. 300 ml/day, p = 0.05; and 1.75 vs. 1.21 l/day, p = 0.023, respectively).


CONCLUSIONS
BIA tertiles categorized PD patients who differed in BNP, RRF and UF in a stepwise pattern, suggesting BIA may better inform hydration status, and serve as an additional clinical tool in management of chronic PD patients.
Mikko
M
Haapio
Paolo
P
Lentini
Andrew A
AA
House
Massimo
M
de Cal
Dinna N
DN
Cruz
Dehua
D
Gong
Maria Pia
MP
Rodighiero
Roberto
R
Dell'Aquila
Claudio
C
Ronco
D000368:Aged; D001834:Body Water / Q000378:metabolism*; D003430:Cross-Sectional Studies; D017097:Electric Impedance; D005260:Female; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010530:Peritoneal Dialysis; D014462:Ultrafiltration
D020097:Natriuretic Peptide, Brain