Malaria: an update for physicians.
Malaria remains the most important parasitic infection in humans. There have been significant advances in the treatment of both nonsevere and severe malaria with the advent of artemisinin combination therapies and parenteral artesunate, but the optimum supportive management of severe malaria is unclear. A broadly acceptable therapy for the prevention of relapses in Plasmodium vivax infection has not been discovered. Globally, the priority remains to prevent infection in the vulnerable, to move toward elimination where feasible, and to ensure that effective treatment is available to all. In developed settings, prevention of infection and its early recognition are crucial.
Department of Clinical Research, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK. behzad.nadjm@lshtm.ac.uk
Behzad
B
Nadjm
Ron H
RH
Behrens
D000962:Antimalarials / Q000627:therapeutic use; D037621:Artemisinins / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008288:Malaria / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology; D010961:Plasmodium / Q000472:pathogenicity; D017410:Practice Guidelines as Topic; D014944:World Health Organization
D000962:Antimalarials; D037621:Artemisinins