Involvement of two-component system CBO0366/CBO0365 in the cold shock response and growth of group I (proteolytic) Clostridium botulinum ATCC 3502 at low temperatures.
The role of the two-component system (TCS) CBO0366/CBO0365 in the cold shock response and growth of the mesophilic Clostridium botulinum ATCC 3502 at 15°C was demonstrated by induced expression of the TCS genes upon cold shock and impaired growth of the TCS mutants at 15°C.
Department of Food Hygiene and Environmental Health, University of Helsinki, Helsinki, Finland. miia.lindstrom@helsinki.fi
Miia
M
Lindström
Elias
E
Dahlsten
Henna
H
Söderholm
Katja
K
Selby
Panu
P
Somervuo
John T
JT
Heap
Nigel P
NP
Minton
Hannu
H
Korkeala
D000064:Acclimatization / Q000502:physiology*; D001426:Bacterial Proteins / Q000378:metabolism*; D003014:Clostridium botulinum / Q000254:growth & development*; D003080:Cold Temperature; D058639:Cold-Shock Response / Q000502:physiology*; D017931:DNA Primers / Q000235:genetics; D000071677:Histidine Kinase; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism; D020133:Reverse Transcriptase Polymerase Chain Reaction; D015398:Signal Transduction / Q000502:physiology*
D001426:Bacterial Proteins; D017931:DNA Primers; D011494:Protein Kinases; D000071677:Histidine Kinase