Outcomes of pancreas allografts procured simultaneously with an isolated intestine allograft:  single-center and national data.
BACKGROUND
Simultaneous procurement of pancreas and isolated intestine allografts from the same donor may compromise one graft or both given the shared vasculature between these two organs. This study reports the transplant outcomes for pancreas allografts procured simultaneously with an intestine graft.


METHODS
Separate analyses are reported from (1) 10-year US national data obtained from the United Network for Organ Sharing database including all donors from 2000 to 2010 in whom both the pancreas and isolated intestine were procured and transplanted into separate recipients and (2) local, single-center data for all donors of simultaneous pancreas and isolated intestine procurement. Scientific Registry of Transplant Recipients reference data are provided for comparison.


RESULTS
Nationally, there were 159 simultaneous pancreas and intestine donors. The mean pancreas transplant graft and patient survival rates for this cohort were 75% and 93%, respectively. There were 34 isolated intestine allografts procured by our center during the study period. There were 14 cases (41%) in which the pancreas was transplanted. The reasons for nontransplantation of the pancreas in the other 20 donors included donor age (n=12), graft quality (n=4), and anatomic or surgical issues (n=4). For the 14 transplanted grafts, 1-year pancreas allograft survival rate was 100%.


CONCLUSIONS
These results suggest that pancreas allografts procured simultaneously with an isolated intestine graft, although technically more challenging, do not have significantly inferior survival outcomes.
Department of Surgery, Indiana University School of Medicine, 550 N. University Blvd.#4258, Indianapolis, IN 46202, USA. jfridell@iupui.edu
Jonathan A
JA
Fridell
Richard S
RS
Mangus
John A
JA
Powelson
Rodrigo M
RM
Vianna
A Joseph
AJ
Tector
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006085:Graft Survival; D006801:Humans; D007422:Intestines / Q000637:transplantation*; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation / Q000401:mortality; D009927:Tissue and Organ Procurement / Q000706:statistics & numerical data; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D014481:United States