Energy expenditure: role of orexin.
The orexins/hypocretins are endogenous, modulatory and multifunctional neuropeptides with prominent influence on several physiological processes. The influence of orexins on energy expenditure is highlighted with focus on orexin action on individual components of energy expenditure. As orexin stabilizes and maintains normal states of arousal and the sleep/wake cycle, we also highlight orexin mediation of sleep and how sleep interacts with energy expenditure.
Department of Nutritional Sciences, University of Arizona and Southern Arizona VA Health Care System, Tucson, Arizona, USA.
Jennifer A
JA
Teske
Vijayakumar
V
Mavanji
D000818:Animals; D004734:Energy Metabolism; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000378:metabolism*; D009043:Motor Activity; D009474:Neurons / Q000378:metabolism*; D009479:Neuropeptides / Q000378:metabolism*; D000068797:Orexins; D012890:Sleep; D009435:Synaptic Transmission
D047908:Intracellular Signaling Peptides and Proteins; D009479:Neuropeptides; D000068797:Orexins