Blindness in a pulseless young woman: lessons learned.
OBJECTIVE
To report a young woman who presented with blindness secondary to ocular ischemic syndrome (OIS) as the initial presenting feature of Takayasu arteritis (TA).


METHODS
Case report.


METHODS
Computer tomography (CT) aortogram showed severely stenosed aortic branches. Fundus fluorescein angiography showed diffuse capillary nonperfusion.


RESULTS
With conventional medical therapy of initial pulse of intravenous methylprednisolone followed by oral steroids and methotrexate, her headache, fatigued feeling, and inflammatory markers improved. However, the visual recovery remained poor.


CONCLUSIONS
OIS in TA may present subacutely and the visual outcome can be poor despite aggressive immunosuppressive therapy.
Rajalingham
R
Sakthiswary
Sharis Osman
SO
Syazarina
Syahrul Sazliyana
SS
Shaharir
Mohd Shahrir Mohd
MS
Said
Faridah
F
Hanom
D001024:Aortic Valve Stenosis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy; D001027:Aortography / Q000379:methods; D001766:Blindness / Q000175:diagnosis* / Q000209:etiology; D005123:Eye / Q000098:blood supply; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008727:Methotrexate / Q000627:therapeutic use; D008775:Methylprednisolone / Q000627:therapeutic use; D012720:Severity of Illness Index; D013625:Takayasu Arteritis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome; D014792:Visual Acuity / Q000187:drug effects; D055815:Young Adult
D007166:Immunosuppressive Agents; D008775:Methylprednisolone; D008727:Methotrexate