[Effects of recombinant mechano-dependent growth factor against the background of chronic alcoholisation in rats].
In alcoholised rats, proliferation of satellite cells consistently decreased as well as the number of myonuclei, while phosphorylation of p90RSK became reduced. The mechano-growth factor abministration increased the proliferate activity of the myogenic precursors and restored the myonuclei pool. Phosphorylation of p90RSK increased too.
E A
EA
Lysenko
O V
OV
Turtikova
E V
EV
Morozkina
V P
VP
Khotchenkov
V O
VO
Popov
B S
BS
Shenkman
D000437:Alcoholism / Q000378:metabolism* / Q000473:pathology; D000818:Animals; D015820:Cadherins / Q000378:metabolism; D002466:Cell Nucleolus / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects*; D005786:Gene Expression Regulation / Q000187:drug effects; D007334:Insulin-Like Growth Factor I / Q000008:administration & dosage*; D008297:Male; D018482:Muscle, Skeletal / Q000166:cytology / Q000378:metabolism*; D051761:Paired Box Transcription Factors / Q000378:metabolism; D010766:Phosphorylation / Q000187:drug effects; D051381:Rats; D038762:Ribosomal Protein S6 Kinases, 70-kDa / Q000378:metabolism; D038744:Ribosomal Protein S6 Kinases, 90-kDa / Q000378:metabolism
D015820:Cadherins; C530821:PAX7 protein, rat; D051761:Paired Box Transcription Factors; C519382:mechano-growth factor, rat; C070896:M-cadherin; D007334:Insulin-Like Growth Factor I; D038762:Ribosomal Protein S6 Kinases, 70-kDa; D038744:Ribosomal Protein S6 Kinases, 90-kDa