Tetanus toxoid reactive lymphadenopathy masquerading as T-cell lymphoma.
We report a case in which a patient with persistent reactive lymphadenopathy post-tetanus toxoid vaccination was initially diagnosed as having T-cell lymphoma/leukemia. A florid CD4+ T-cell proliferation and pathology interpretation, in the absence of complete clinical information, that these cells co-expressed CD8 led to the initial diagnosis. Better integration of the clinical and pathologic data may have led more rapidly to the final diagnosis. Postvaccination responses can mimic lymphoma.
Dept of Medical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA 19111, USA.
Christine K
CK
White
Tahseen
T
Al-Saleem
Alan Pz
AP
Skarbnik
Mitchell R
MR
Smith
D001132:Arm; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008206:Lymphatic Diseases / Q000175:diagnosis* / Q000276:immunology*; D016399:Lymphoma, T-Cell / Q000175:diagnosis*; D008875:Middle Aged; D013745:Tetanus Toxoid / Q000276:immunology*
D013745:Tetanus Toxoid