[Cultured cell systems for revelation of new drugs antiatherosclerotic effects and their mechanisms investigation].
Cultured cell models have been developed to study the cholesterol efflux from the arterial wall as an integral indicator of reverse cholesterol transport. The models and the results of in vivo and ex vivo experiments can be used to propose new antiatherosclerotic drugs and elucidate their mood of action.
A N
AN
Orekhov
I A
IA
Sobenin
V A
VA
Orekhova
A A
AA
Mel'nichenko
V A
VA
Miasoedova
N M
NM
Mukhamedova
D M
DM
Martirosian
A V
AV
Pshezhetskiĭ
V P
VP
Karagodin
D000328:Adult; D000924:Anticholesteremic Agents / Q000737:chemistry / Q000494:pharmacology*; D001158:Arteries / Q000378:metabolism* / Q000473:pathology; D050197:Atherosclerosis / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D002478:Cells, Cultured; D002784:Cholesterol / Q000378:metabolism*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008954:Models, Biological
D000924:Anticholesteremic Agents; D002784:Cholesterol