[Melatonin as a marker of intensity of structural and functional changes in the heart and vessels of the patients presenting with metabolic syndrome].
It is known that pathological characteristics of cardiac rhythm variability, endothelial dysfunction, and left ventricular hypertrophy may be used as independent predictors of cardiovascular complications; their combination with metabolic disorders increases severalfold the risk of cardiovascular catastrophes. The patients presenting with metabolic syndrome are characterized by the interrelation between melatonin hypersecretion, parameters of hyperactivity of the sympathetic component of the nervous system, and prognostically unfavourable variants of cardiac and vascular remodeling (including endothelial dysfunction, concentric remodeling and concentric myocardial ventricular hypertrophy). These correlations have age-specific peculiarities.
T N
TN
Grinenko
M F
MF
Balliuzek
T V
TV
Kvetnaia
D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000378:metabolism; D001808:Blood Vessels / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008550:Melatonin / Q000378:metabolism*; D024821:Metabolic Syndrome / Q000378:metabolism* / Q000473:pathology*; D008875:Middle Aged; D009206:Myocardium / Q000378:metabolism* / Q000473:pathology*; D011379:Prognosis
D015415:Biomarkers; D008550:Melatonin