Evaluation of simulant migration of volatile nitrosamines from latex gloves and balloons by HS-SPME-GC-MS.
Nitrosamines are a group of carcinogens that have been found in various latex products. Methods have been developed for extraction, concentration and detection of simulant migration of volatile nitrosamines from latex gloves and balloons. After glove samples or balloon samples were treated with artificial sweat and artificial saliva, headspace solid-phase microextraction and gas chromatography with mass spectrometer detection were performed. Eight volatile nitrosamines were extracted by a fused silica fiber coated with carboxen-polydimethylsioxane, and solid-phase microextraction conditions were optimized. The developed method was successfully used to analyze simulant migration of volatile nitrosamines from latex gloves and balloons. The described methods are rapid and simple, with adequate sensitivity and without organic solvent.
Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.
Di
D
Feng
Luo
L
Liu
Liyuan
L
Zhao
Qingfeng
Q
Zhou
Tianwei
T
Tan
D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D017575:Gloves, Protective; D007840:Latex / Q000737:chemistry*; D016014:Linear Models; D008956:Models, Chemical; D009602:Nitrosamines / Q000032:analysis / Q000737:chemistry* / Q000302:isolation & purification; D015203:Reproducibility of Results; D012463:Saliva / Q000737:chemistry; D012680:Sensitivity and Specificity; D052617:Solid Phase Microextraction / Q000379:methods*; D013542:Sweat / Q000737:chemistry; D013696:Temperature
D007840:Latex; D009602:Nitrosamines