Serum levels of marine-derived n-3 fatty acids in Icelanders, Japanese, Koreans, and Americans--a descriptive epidemiologic study.
In the 1990s Iceland and Japan were known as countries with high fish consumption whereas coronary heart disease (CHD) mortality in Iceland was high and that in Japan was low among developed countries. We described recent data fish consumption and CHD mortality from publicly available data. We also measured CHD risk factors and serum levels of marine-derived n-3 and other fatty acids from population-based samples of 1324 men in Iceland, Japan, South Korea, and the US. CHD mortality in men in Iceland was almost 3 times as high as that in Japan and South Korea. Generally, a profile of CHD risk factors in Icelanders compared to Japanese was more favorable. Serum marine-derived n-3 fatty acids in Iceland were significantly lower than in Japan and South Korea but significantly higher than in the US.
University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA 15213, USA. akira@pitt.edu
Akira
A
Sekikawa
Laufey
L
Steingrimsdottir
Hirotsugu
H
Ueshima
Chol
C
Shin
J David
JD
Curb
Rhobert W
RW
Evans
Alda M
AM
Hauksdottir
Aya
A
Kadota
Jina
J
Choo
Kamal
K
Masaki
Bolli
B
Thorsson
Lenore J
LJ
Launer
Melisa E
ME
Garcia
Hiroshi
H
Maegawa
Bradley J
BJ
Willcox
Gudny
G
Eiriksdottir
Akira
A
Fujiyoshi
Katsuyuki
K
Miura
Tamara B
TB
Harris
Lewis H
LH
Kuller
Vilmundur
V
Gudnason
D000328:Adult; D001213:Asian; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000097:blood* / Q000208:ethnology / Q000209:etiology / Q000401:mortality; D015525:Fatty Acids, Omega-3 / Q000097:blood*; D006801:Humans; D007055:Iceland / Q000453:epidemiology; D007564:Japan / Q000453:epidemiology / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D017747:Seafood; D014481:United States / Q000453:epidemiology
D015525:Fatty Acids, Omega-3; D002784:Cholesterol