Carcinoma erysipeloides of laryngeal origin.
The term "carcinoma erysipeloides" (CE) designates an uncommon form of cutaneous metastasis. CE is most often associated with carcinoma of the breast. However, there have been reports of CE from carcinoma of the uterus, prostate, lung, ovary, stomach, tonsils, thyroid, pancreas, rectum, parotid glands and melanoma. To our knowledge, CE of laryngeal origin has not been previously reported. We describe a patient diagnosed with human immunodeficiency virus and hepatitis C virus coinfection who developed a supraglottic laryngeal squamous cell carcinoma and erythematous cutaneous lesions. A skin biopsy demonstrated invasion of dilated dermal lymphatics by clusters of atypical squamous cells with polymorphic nuclei and extensive infiltration of the dermis by tumor cells. The histology of the metastatic cells was similar to that of the laryngeal carcinoma.
Department of Dermatology, University Hospital Reina Sofía, Córdoba, Spain. airam_al@hotmail.com
María Á
MÁ
Álvarez
Enrique
E
Casas
Juan
J
Ruano
Antonio
A
Vélez
Juan
J
Salvatierra
Jose C
JC
Moreno
D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000556:secondary* / Q000628:therapy; D060085:Coinfection; D017809:Fatal Outcome; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy; D006526:Hepatitis C / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D042601:Lymphatic Vessels / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000150:complications / Q000556:secondary* / Q000628:therapy; D016896:Treatment Outcome