The mean platelet volume and atherogenic index of plasma in nondipper normotensive individuals compared to dippers.
Mean platelet volume (MPV) is a determinant of platelet activation. Atherogenic index of plasma (AIP), which is defined as the logarithm of the ratio of plasma level of triglycerides to the level of high-density lipoprotein (HDL)-cholesterol (log[ TG/HDL-C]), has recently been used as a marker of atherogenicity. This study included 104 normotensive individuals. Mean platelet volume and AIP were measured in all patients. Nondipper individuals (8.6 ± 0.9 fL, 0.3 ± 0.2) demonstrated higher values of MPV and AIP compared with dippers (7.9 ± 1.1 fL, 0.1 ± 0.2) (P < .001 and < .001, respectively). Mean platelet volume and AIP have a positive correlation with insufficient decline in nocturnal blood pressure.
Atatürk State Hospital, Clinic of Nephrology, Zonguldak, Turkey. drgursel@yahoo.com
Gürsel
G
Yildiz
Ender
E
Hür
Adalet
A
Özçiçek
Ferhan
F
Candan
Mansur
M
Kayatas
D000328:Adult; D050197:Atherosclerosis / Q000097:blood* / Q000209:etiology / Q000503:physiopathology*; D015415:Biomarkers / Q000097:blood; D001792:Blood Platelets / Q000166:cytology*; D001794:Blood Pressure / Q000502:physiology*; D016022:Case-Control Studies; D008076:Cholesterol, HDL / Q000097:blood; D002940:Circadian Rhythm / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015539:Platelet Activation / Q000502:physiology*; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
D015415:Biomarkers; D008076:Cholesterol, HDL; D014280:Triglycerides