Lethal effects of Aspergillus niger against mosquitoes vector of filaria, malaria, and dengue: a liquid mycoadulticide.
Aspergillus niger is a fungus of the genus Aspergillus. It has caused a disease called black mold on certain fruits and vegetables. The culture filtrates released from the A. niger ATCC 66566 were grown in Czapek dox broth (CDB) then filtered with flash chromatograph and were used for the bioassay after a growth of thirty days. The result demonstrated these mortalities with LC(50), LC(90), and LC(99) values of Culex quinquefasciatus 0.76, 3.06, and 4.75, Anopheles stephensi 1.43, 3.2, and 3.86, and Aedes aegypti 1.43, 2.2, and 4.1 μl/cm(2), after exposure of seven hours. We have calculated significant LT(90) values of Cx. quinquefasciatus 4.5, An. stephensi 3.54, and Ae. aegypti 6.0 hrs, respectively. This liquid spray of fungal culture isolate of A. niger can reduce malaria, dengue, and filarial transmission. These results significantly support broadening the current vector control paradigm beyond chemical adulticides.
Environmental and Advanced Parasitology and Vector Control Biotechnology Laboratories, Department of Zoology, Faculty of Science, Dayalbagh Educational Institute, Dayalbagh, Agra 282005, India.
Gavendra
G
Singh
Soam
S
Prakash
D000818:Animals; D001234:Aspergillus niger / Q000737:chemistry*; D009033:Culicidae / Q000821:virology*; D003716:Dengue Virus; D004305:Dose-Response Relationship, Drug; D007303:Insect Vectors / Q000187:drug effects* / Q000821:virology*; D007306:Insecticides / Q000008:administration & dosage* / Q000302:isolation & purification / Q000494:pharmacology*; D007928:Lethal Dose 50; D010961:Plasmodium; D012996:Solutions; D015996:Survival Rate
D007306:Insecticides; D012996:Solutions