Low prevalence of Leishmania infection in post-epidemic areas of Libo Kemkem, Ethiopia.
In Libo Kemkem (a district of Amhara region, Ethiopia), no cases of kala-azar had ever been reported until 2005 when an outbreak occurred. Over one-third of those cases were children under 15 years of age. The aim of the present study was to determine the prevalence of Leishmania infection in children aged 4-15 years. A cross-sectional survey was conducted in 2009. Children participating in the survey were selected using a three-stage cluster sampling method. A total of 386 children were included in the study. The overall prevalence of Leishmania infection (direct agglutination test- and/or rK39 immunochromatographic test- and/or leishmanin skin test-positive subjects) in this population was 1.02% (95% confidence interval = 0-4.54), and prevalence was higher in boys and children older than 12 years. Only one case of active disease was encountered. The results suggest that the conditions responsible for the outbreak no longer reign. However, active surveillance remains necessary.
Centro Nacional de Epidemiología, Instituto de Salud Carlos III, CIBER en Epidemiología y Salud Pública (CIBERESP), Madrid, Spain. lsordo@isciii.es
Luis
L
Sordo
Endalamaw
E
Gadisa
Estefanía
E
Custodio
Israel
I
Cruz
Fernando
F
Simón
Zelalem
Z
Abraham
Javier
J
Moreno
Abraham
A
Aseffa
Hailu
H
Tsegaye
Javier
J
Nieto
Carmen
C
Chicharro
Carmen
C
Cañavate
D000293:Adolescent; D000372:Agglutination Tests / Q000379:methods; D000953:Antigens, Protozoan / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D058872:Epidemics; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D006801:Humans; D007891:Leishmania / Q000254:growth & development / Q000472:pathogenicity*; D007898:Leishmaniasis, Visceral / Q000453:epidemiology*; D008297:Male; D015995:Prevalence; D012882:Skin Tests / Q000379:methods
D000953:Antigens, Protozoan; C032127:leishmanin