The INs and OUTs of pattern recognition receptors at the cell surface.
Pattern recognition receptors (PRRs) enable plants to sense non-self molecules displayed by microbes to mount proper defense responses or establish symbiosis. In recent years the importance of PRR subcellular trafficking to plant immunity has become apparent. PRRs traffic through the endoplasmatic reticulum (ER) and the Golgi apparatus to the plasma membrane, where they recognize their cognate ligands. At the plasma membrane, PRRs can be recycled or internalized via endocytic pathways. By using genetic and biochemical tools in combination with bioimaging, the trafficking pathways and their role in PRR perception of microbial molecules are now being revealed.
The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK.
Martina
M
Beck
William
W
Heard
Malick
M
Mbengue
Silke
S
Robatzek
D001419:Bacteria / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism*; D060467:Disease Resistance / Q000276:immunology*; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D006056:Golgi Apparatus / Q000378:metabolism*; D054884:Host-Pathogen Interactions / Q000276:immunology; D057865:Plant Immunity / Q000502:physiology; D010944:Plants / Q000276:immunology* / Q000378:metabolism / Q000382:microbiology*; D051192:Receptors, Pattern Recognition / Q000276:immunology*; D015398:Signal Transduction / Q000502:physiology; D013559:Symbiosis / Q000502:physiology
D051192:Receptors, Pattern Recognition