Life-threatening calcium channel blocker overdose and its management.
A young woman presented to the emergency department with complaints of nausea, vomiting, pain in the abdomen and difficulty in breathing after ingestion of 56 tablets of amlodipine 5 mg each (total 280 mg of amlodipine). She was managed using hyperinsulinaemia/euglycaemia therapy and other measures like calcium gluconate, glucagon and vasopressors. She was discharged from hospital in a stable condition after 5 days.
Department of General Medicine, J N Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India. imranrizvi09@gmail.com
Imran
I
Rizvi
Ajaz
A
Ahmad
Ankush
A
Gupta
Shamsuz
S
Zaman
D017311:Amlodipine / Q000506:poisoning*; D002121:Calcium Channel Blockers / Q000506:poisoning*; D062787:Drug Overdose / Q000628:therapy*; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use*; D012151:Resuscitation / Q000379:methods*; D055815:Young Adult
D002121:Calcium Channel Blockers; D007004:Hypoglycemic Agents; D007328:Insulin; D017311:Amlodipine