Epicardial left atrial appendage clip occlusion also provides the electrical isolation of the left atrial appendage.
OBJECTIVE
The exclusion of the left atrial appendage (LAA) has been used to reduce the risk of stroke associated with atrial fibrillation (AF). While LAA exclusion has been associated with a reduced risk of stroke, the effect on the electrical activity of the LAA (a potential source of AF) remains unknown. As such, we sought to demonstrate whether surgical epicardial clip occlusion leads to the electrical isolation of the LAA.


METHODS
From December 2010 until August 2011, 10 patients with paroxysmal AF underwent off-pump coronary artery bypass surgery with bilateral pulmonary vein isolation and an LAA clip occlusion with a new epicardial clip. Before and after the clip was placed, pacing manoeuvres were performed to assess the electrical exit and entry blocks from the LAA.


RESULTS
All clips were applied successfully. The mean procedure time for the clip application was 4 ± 1 min. No complications occurred related to clip application. Prior to the pericardial closure, 18 ± 3 min after the clip placement, the LAA stimulation and pacing manoeuvres demonstrated complete electrical isolation of the LAA in all cases.


CONCLUSIONS
Epicardial LAA clip occlusion leads to the acute electrical isolation of the LAA and may not only provide stroke prevention but also reduce the recurrence of AF.
Department of Cardiovascular Surgery,  University Hospital Zurich, Zurich,  Switzerland.
Christoph T
CT
Starck
Jan
J
Steffel
Maximilian Y
MY
Emmert
Andre
A
Plass
Srijoy
S
Mahapatra
Volkmar
V
Falk
Sacha P
SP
Salzberg
D000368:Aged; D020517:Atrial Appendage / Q000601:surgery*; D001281:Atrial Fibrillation / Q000150:complications / Q000601:surgery*; D017115:Catheter Ablation / Q000295:instrumentation*; D047549:Coronary Artery Bypass, Off-Pump / Q000295:instrumentation*; D004556:Electric Injuries / Q000517:prevention & control*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010496:Pericardium / Q000601:surgery*; D019736:Prostheses and Implants; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D016896:Treatment Outcome