[Characterization of depression-like behavior in prenatally stressed female rats during ovary cycle].
The aim of the present work was a comparative analysis of dynamics of depression-like behavior in prenatally stressed and non-prenatally stressed female rats in the key phases of the ovary cycle. It was found that non-stressed female rats demonstrated high level of depression-like behavior in proestrous phase as compared to the diestrous phase, whereas these rats showed low level of depression-like behavior in estrous phase in Porsolt's test. On the contrary, there were no significant differences in extent of depression-like behavior between prenatally stressed rats in the diestrous and proestrous, although in the phase of estrous in these animals an increase in level of depression-like behavior was noted. Thus, the results of this study indicated pronounced effects of prenatal stress on the character of depression-like behavior of females in different phases of ovary cycle. This study revealed leveling and reversed action of prenatal stress on depression-like behavior in key phases of sexual cycle in female rats.
Iu O
IuO
Fedotova
N N
NN
Kriukova
S G
SG
Pivina
N E
NE
Ordian
D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D003863:Depression / Q000503:physiopathology*; D004971:Estrus / Q000502:physiology*; D005260:Female; D005082:Physical Exertion; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D017208:Rats, Wistar; D012726:Sexual Behavior, Animal; D013312:Stress, Physiological; D013550:Swimming