Polyhydroxylated steroidal glycosides from Paris polyphylla.
Three new steroidal saponins, parisyunnanosides G-I (1-3), one new C(21) steroidal glycoside, parisyunnanoside J (4), and three known compounds, padelaoside B (5), pinnatasterone (6), and 20-hydroxyecdyson (7), were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Compounds 1 and 3 have unique trisdesmoside structures that include a C-21 β-d-galactopyranose moiety. All compounds were evaluated for their cytotoxicity against human CCRF leukemia cells.
Beijing Institute of Radiation Medicine, Beijing 100850, People's Republic of China.
Li-Ping
LP
Kang
Yi-Xun
YX
Liu
Tolga
T
Eichhorn
Else
E
Dapat
He-shui
HS
Yu
Yang
Y
Zhao
Cheng-Qi
CQ
Xiong
Chao
C
Liu
Thomas
T
Efferth
Bai-Ping
BP
Ma
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D019668:Liliaceae / Q000737:chemistry*; D015394:Molecular Structure; D027343:Rhizome / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D012503:Saponins; D013256:Steroids