[Determination of bisphenol A in plastic parts of small household appliances by liquid chromatography-tandem mass spectrometry].
A method for the determination of bisphenol A in the plastic parts of small household appliances by liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed. The sample was extracted with accelerated solvent extraction (ASE) and purified by Sep-Pak C18 solid phase extraction. Bisphenol A was separated and detected using LC-MS/MS in negative ion mode with the mobile phases of methanol and water (containing 0.05% ammonia water). The linearity of the method was good in the range of 5 μg/L to 100 μg/L. The recoveries for the spiked sample were from 95.2% to 109.7% at the three levels, 10, 25 and 75 μg/kg. The relative standard deviations were less than 3.8%. The limit of detection was 10 μg/kg. The method is easy-handling, time-saving, sensitive and suitable for the determination of the residual bisphenol A in the plastic parts of household appliances.
Beijing Entry-Exit Inspection and Quarantine Bureau, Beijing 100026, China.
Yan
Y
Zhang
Xiaofei
X
Ma
Pin
P
Lü
Hui
H
Li
Xiaoyu
X
Lu
D001559:Benzhydryl Compounds / Q000032:analysis*; D002853:Chromatography, Liquid / Q000379:methods; D004785:Environmental Pollutants / Q000032:analysis; D006794:Household Articles; D010636:Phenols / Q000032:analysis*; D010969:Plastics / Q000737:chemistry*; D053719:Tandem Mass Spectrometry / Q000379:methods; D000098826:Bisphenol A Compounds
D001559:Benzhydryl Compounds; D004785:Environmental Pollutants; D010636:Phenols; D010969:Plastics; C006780:bisphenol A; D000098826:Bisphenol A Compounds