The effects of body acupuncture on obesity: anthropometric parameters, lipid profile, and inflammatory and immunologic markers.
A randomized controlled clinical trial in 196 obese subjects was performed to examine the effectiveness of body acupuncture on body weight loss, lipid profile and immunogenic and inflammatory markers. Subjects received authentic (cases) or sham (controls) acupuncture for 6 weeks in combination with a low-calorie diet. In the following 6 weeks, they received the low-calorie diet alone. Subjects were assessed at the beginning, 6 and 12 weeks later. Heat shock protein (Hsps)-27, 60, 65, 70 antibody titers and high sensitivity C-reactive protein (hs-CRP) levels were also assessed. A significant reduction in measures of adiposity and improvement in lipid profile were observed in both groups, but the levels of anti-Hsp-antibodies decreased in cases only. A reduction in anthropometric and lipid profile in cases were sustained in the second period, however, only changes in lipid profile were observed in the control group. Anti-Hsp-antibodies and hs-CRP levels continued to be reduced in cases but in controls only the reduction in hs-CRP remained. Changes in anthropometric parameters, lipid profile, and anti-Hsp-antibodies were more evident in cases. Body acupuncture in combination with diet restriction was effective in enhancing weight loss and improving dyslipidemia.
Departments of Acupuncture Therapy, Beijing University of Chinese Medicine, Beijing 100029, China.
Hamid
H
Abdi
Baixiao
B
Zhao
Mahsa
M
Darbandi
Majid
M
Ghayour-Mobarhan
Shima
S
Tavallaie
Amir Ali
AA
Rahsepar
Seyyed Mohammad Reza
SM
Parizadeh
Mohammad
M
Safariyan
Mohsen
M
Nemati
Maryam
M
Mohammadi
Parisa
P
Abbasi-Parizad
Sara
S
Darbandi
Saeed
S
Akhlaghi
Gordon A A
GA
Ferns
D015670:Acupuncture Therapy; D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D015415:Biomarkers; D015992:Body Mass Index; D001835:Body Weight; D002097:C-Reactive Protein / Q000378:metabolism; D031204:Caloric Restriction; D006360:Heat-Shock Proteins / Q000276:immunology*; D006801:Humans; D008055:Lipids / Q000097:blood*; D008875:Middle Aged; D009765:Obesity / Q000628:therapy*; D015431:Weight Loss
D015415:Biomarkers; D006360:Heat-Shock Proteins; D008055:Lipids; D002097:C-Reactive Protein