A feasible shortcut for the mobilization outcome: Steady state CD34 positive hematopoietic stem cells.
Predicting success of hematopoietic cell mobilization is an important issue for transplant physicians. We examined the steady state peripheral blood CD34+ cell count to predict ability to mobilize adequate hematopoietic progenitor cells in 63 myeloma and lymphoma patients. The median steady state CD34+ cell number was 1.56/μL (0.03-5.76). Although counting steady state CD34+ is definitely cost effective to predict the successful mobilization, we could not find a threshold steady state CD34 count of any value predicting successful mobilization.
Ankara Oncology Research and Education Hospital, Hematology and Stem Cell Transplantation Unit, Ankara, Turkey. meltemkurt@hotmail.com
Meltem Kurt
MK
Yüksel
Emre
E
Tekgündüz
Cigdem
C
Sönmez
Pervin
P
Topcuoglu
Arzu
A
Yurtcu
Itır
I
Demiriz
Ayşegül
A
Tetik
Omür
O
Kayıkçı
Murat
M
Cınarsoy
Fevzi
F
Altuntaş
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D019650:Hematopoietic Stem Cell Mobilization / Q000379:methods*; D006412:Hematopoietic Stem Cells; D006801:Humans; D007958:Leukocyte Count; D008223:Lymphoma; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma; D036102:Peripheral Blood Stem Cell Transplantation; D014182:Transplantation, Autologous