Pharmaceutical structure montages as catalysts for design and discovery.
Majority of pharmaceuticals are small molecule organic compounds. Their structures are most effectively described and communicated using the graphical language of organic chemistry. A few years ago we decided to harness this powerful language to create new educational tools that could serve well for data mining and as catalysts for discovery. The results were the Top 200 drug posters, which we have posted online for everyone to enjoy and update yearly. This article details the origin and motivation for our design and highlights the value of this graphical format by presenting and analyzing a new pharmaceutical structure montage (poster) focused on US FDA approved drugs in 2011.
Department of Chemistry & Biochemistry, University of Arizona, 1306 E. University Boulevard, Tucson, AZ 85721, USA. njardars@email.arizona.edu
Jon T
JT
Njarðarson
D057225:Data Mining; D015195:Drug Design; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D054852:Small Molecule Libraries / Q000737:chemistry*; D014481:United States; D014486:United States Food and Drug Administration
D004364:Pharmaceutical Preparations; D054852:Small Molecule Libraries