Quantum dots for molecular diagnostics of tumors.
Semiconductor quantum dots (QDs) are a new class of fluorophores with unique physical and chemical properties, which allow to appreciably expand the possibilities for the current methods of fluorescent imaging and optical diagnostics. Here we discuss the prospects of QD application for molecular diagnostics of tumors ranging from cancer-specific marker detection on microplates to non-invasive tumor imagingin vivo. We also point out the essential problems that require resolution in order to clinically promote QD, and we indicate innovative approaches to oncology which are implementable using QD.
Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences.
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Zdobnova
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Lebedenko
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Deyev