Elevated troponin T levels in a female carrier of Duchenne muscular dystrophy with normal coronary angiogram: a case report and review of the literature.
We present the case of a 48-year-old female carrier of Duchenne muscular dystrophy (DMD) with repeatedly documented levels of elevated troponin T without arguments for cardiac ischaemia. Elevated levels of troponin T are frequently reported in DMD patients and may function as a useful cardiac index to assess dystrophic degeneration of the myocardium in a subclinical stage. Cardiac troponins may help the clinician to diagnose myocardial damage in a very early stage of cardiac impairment independently from skeletal muscle degeneration.
Department of Cardiology, Sint Blasius Hospital, Dendermonde, Belgium. jadpoote.depooter@ugent.be
Jan
J
De Pooter
Joke
J
Vandeweghe
An
A
Vonck
Peter
P
Loth
Joost
J
Geraedts
D015415:Biomarkers / Q000097:blood; D017023:Coronary Angiography; D005260:Female; D006331:Heart Diseases / Q000097:blood* / Q000175:diagnosis; D006579:Heterozygote; D006801:Humans; D008875:Middle Aged; D020388:Muscular Dystrophy, Duchenne / Q000097:blood* / Q000235:genetics*; D009206:Myocardium / Q000378:metabolism / Q000473:pathology; D020107:Troponin T / Q000097:blood*
D015415:Biomarkers; D020107:Troponin T