[Features of hormone metabolism in reproductive age women with metabolic syndrome].
Aim of this study was the investigation of feature of hormonal status in patients with metabolic syndrome (MetS). 111 reproductive age women were included in the study. According to diagnostic criteria for MetS of Society of Cardiology of the Russian Federation (2009) they were divided into two groups--study group (n=52) and control group (n=59). It was studied composition of body (fat mass, skeletal mass, lean mass, total, intracellular and extracellular fluid), parameter of lipid and carbohydrate metabolism, parameter of hormonal status. Study of hormonal status in reproductive age women with MetS showed a higher level of fasting and postprandial levels of insulin and C-peptide, hyperleptinemia and a reduced level of sex hormone-binding globulinn (SHBG). We suggest that serum leptin and SHBG levels may be used as an additional diagnostic criteria in these patients.
A V
AV
Iudochkin
Kh Kh
KhKh
Sharafetdinov
O A
OA
Plotnikova
R I
RI
Alekseeva
T B
TB
Sentsova
I V
IV
Vorozhko
D000273:Adipose Tissue / Q000378:metabolism; D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D001774:Blood Chemical Analysis; D001823:Body Composition; D015992:Body Mass Index; D002096:C-Peptide / Q000097:blood; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood* / Q000378:metabolism; D006304:Health Status; D006801:Humans; D007328:Insulin / Q000097:blood; D020738:Leptin / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000378:metabolism* / Q000503:physiopathology; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism; D012098:Reproduction; D012307:Risk Factors; D012738:Sex Hormone-Binding Globulin / Q000032:analysis* / Q000378:metabolism; D014280:Triglycerides / Q000097:blood; D049629:Waist-Hip Ratio
D015415:Biomarkers; D002096:C-Peptide; D012739:Gonadal Steroid Hormones; D007328:Insulin; D020738:Leptin; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D012738:Sex Hormone-Binding Globulin; D014280:Triglycerides