Chronic non-granulomatous supraglottitis: a rare and difficult disease.
OBJECTIVE
To examine chronic non-granulomatous supraglottitis, a rare disorder of uncertain aetiology with few reported cases in the literature.


METHODS
We describe two cases of chronic non-granulomatous supraglottitis that led to persistent respiratory compromise. Patients underwent extensive investigation that failed to reveal a definitive diagnosis.


CONCLUSIONS
In patients suffering from chronic inflammation of the supraglottic larynx without evidence of infection, neoplasm or granulomatous disease, many disorders must be ruled out in order to diagnose chronic non-granulomatous supraglottitis, which is a diagnosis of exclusion. We review the literature on this rare entity, discuss current management strategies, and suggest an algorithm for diagnostic investigation.
Center for Voice and Swallowing, University of California, Sacramento, CA 95817, USA.
L G
LG
Ledgerwood
P C
PC
Belafsky
D000328:Adult; D003937:Diagnosis, Differential; D004825:Epiglottis / Q000473:pathology; D005260:Female; D006102:Granuloma, Laryngeal / Q000175:diagnosis*; D006801:Humans; D007818:Laryngeal Diseases / Q000175:diagnosis* / Q000628:therapy; D007828:Laryngoscopy; D008297:Male; D059525:Supraglottitis / Q000175:diagnosis* / Q000628:therapy