Current ultrafiltration techniques before, during and after pediatric cardiopulmonary bypass procedures.
Ultrafiltration, which is currently considered as a standard method to remove excess water administered during pediatric cardiopulmonary bypass (CPB), aims to minimize the adverse effects of hemodilution, such as tissue edema and blood transfusion. Three ultrafiltration techniques can be used before, during and after CPB procedures, including conventional ultrafiltration (CUF), modified ultrafiltration (MUF) and zero-balance ultrafiltration (Z-BUF). These methods are widely different, but they have common benefits on hemoconcentration, less requirement for blood products, and reduction of the systemic inflammatory responses (SIRS). The present review attempts to restate these ultrafiltration circuitries, application methods, end-points, and clinical impacts.
Penn State Hershey Pediatric Cardiovascular Research Center, Department of Pediatrics, Penn State Milton S. Hershey Medical Center, Penn State Hershey College of Medicine, Penn State Hershey Children's Hospital, Hershey, Pennsylvania, USA.
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Wang
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Palanzo
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Ündar
D001803:Blood Transfusion / Q000379:methods; D002315:Cardiopulmonary Bypass / Q000379:methods*; D002675:Child, Preschool; D006438:Hemodilution / Q000379:methods; D006440:Hemofiltration / Q000379:methods*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010372:Pediatrics / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014462:Ultrafiltration / Q000379:methods