Water-dispersible and biodegradable polymer micelles with good antibacterial efficacy.
New amphiphilic ABC triblock copolymers have been designed and self-assembled into water-dispersible and biodegradable polymer micelles, which exhibit good antibacterial activities without quaternary ammonium moieties or the loading of any external antibiotics due to the increased local concentration of cationic charge in the polymer micelles compared to the un-self-assembled individual polymer chains.
School of Materials Science and Engineering, Tongji University, 4800 Caoan Road, Shanghai 201804, People's Republic of China.
Weizhong
W
Yuan
Jingren
J
Wei
Hang
H
Lu
Lang
L
Fan
Jianzhong
J
Du
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D002412:Cations / Q000737:chemistry; D004926:Escherichia coli / Q000187:drug effects; D008823:Micelles; D011108:Polymers / Q000737:chemistry* / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects; D014867:Water / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D002412:Cations; D008823:Micelles; D011108:Polymers; D014867:Water