Periodic sterility assessment of materials stored for up to 6 months at continuous microbial contamination risk: laboratory study.
An investigation was conducted to test the hypothesis that the storage time of packaging sterility has no effect on contamination susceptibility even under deliberate bacterial exposure (Serratia marcescens). No growth of the test microorganisms was identified in the experimental group in any of the storage intervals (7, 14, 28, 90, and 180 days). Current recommendations/guidelines suggest that contamination of packaging occurs only because of events. This study, done in vitro, supports these recommendations.
Department of Medical Surgical Nursing, School of Nursing, University of São Paulo, São Paulo, Brazil. gaamoriya@gmail.com
Giovana Abrahão de Araújo
GA
Moriya
Rafael Queiroz de
RQ
Souza
Flávia Morais Gomes
FM
Pinto
Kazuko Uchikawa
KU
Graziano
D004864:Equipment and Supplies / Q000382:microbiology*; D006801:Humans; D019064:Product Packaging / Q000379:methods*; D012706:Serratia marcescens / Q000302:isolation & purification; D013997:Time Factors