Tetracycline resistance genes and mobile genetic elements from the oral metagenome.
Tetracycline resistance genes are common in the human oral cavity. However, a complete understanding of tetracycline resistance and the vectors responsible for spread of resistance requires that we understand the contribution of organisms that cannot be cultivated in the laboratory. To do this, metagenomic approaches have been applied and this has allowed the isolation of novel tetracycline resistance genes and mobile genetic elements.
University College Eastman Dental Institute, 256 Gray's Inn Road University College, London WC1X 8LD, UK. p.mullany@ucl.ac.uk
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P
Mullany
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Allan
P J
PJ
Warburton
D005798:Genes, Bacterial; D006801:Humans; D020071:Interspersed Repetitive Sequences; D054892:Metagenome; D009055:Mouth / Q000382:microbiology*; D013753:Tetracycline Resistance