New horizons in treating disorders of hyperpigmentation in skin of color.
Pigmentary abnormalities are among the most common reasons why patients with skin of color visit a dermatologist. Hydroquinone has been a cornerstone for the treatment of hyperpigmentation; however, concerns regarding adverse effects have prompted a search for alternative agents. Some promising topical treatments include soy, licorice, rucinol, mulberry, niacinamide, ellagic acid, resveratrol, and dioic acid. Oral agents, primarily used for the prevention of postprocedural hyperpigmentation, include procyanidins, tranexamic acid, and Polypodium leucotomos. Advances in Q-switched lasers, intense pulse light, fractional photothermolysis, and the advent of tretinoin peeling add to the clinician's armamentarium for treating hyperpigmentation.
Department of Dermatology, Howard University College of Medicine, Washington, DC 20060, USA.
Sailesh
S
Konda
Aanand N
AN
Geria
Rebat M
RM
Halder
D006801:Humans; D000284:Administration, Oral; D000287:Administration, Topical; D002615:Chemexfoliation / Q000379:methods; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D006873:Hydroquinones / Q000009:adverse effects; D017495:Hyperpigmentation / Q000208:ethnology / Q000517:prevention & control / Q000628:therapy; D053685:Laser Therapy / Q000379:methods; D011837:Radiation-Protective Agents / Q000009:adverse effects; D000091762:Ethnic and Racial Minorities
D003879:Dermatologic Agents; C031927:hydroquinone; D006873:Hydroquinones; D011837:Radiation-Protective Agents