Determination of vitamin A in infant formula and adult nutritionals by UPLC-UV: First Action 2011.07.
Vitamin A, a fat-soluble vitamin, is essential for health and plays an important part in vision, bone growth, reproduction, regulating the immune system, cell function, and skin health. Due to the advances in technology and the expansion of its uses, LC technologies are being studied for effectiveness in detecting and quantifying vitamin A in an effort to help determine the amount of vitamin A in various types of samples. For this reason, an Expert Review Panel agreed on June 29, 2011, at the "Standards Development and International Harmonization: AOAC INTERNATIONAL Mid-Year Meeting," to approve "Determination of Vitamin A in Infant Formula and Adult Nutritionals by UPLC-UV" as AOAC Official Method 2011.07. To move from First to Final Action status, it was recommended that additional information be generated for all types of infant formulas and adult nutritional formula matrixes at varied concentration levels, as indicated in the standard method performance requirements. International units or retinol equivalents typically represent the concentration of vitamin A in food and supplements. However, for the purpose of this method, the concentration represented is presented in microg/100 g.
Nestlé Quality Assurance Center, 6625 Eiterman Rd, Dublin, OH, USA.
Marie-José
MJ
Trisconi
Esther
E
Campos-Gimenez
Greg
G
Jaudzems
Dawn
D
Dowell
D000328:Adult; D002648:Child; D002853:Chromatography, Liquid / Q000379:methods*; D005504:Food Analysis / Q000379:methods; D005526:Food, Formulated / Q000032:analysis*; D006801:Humans; D007223:Infant; D041943:Infant Formula / Q000737:chemistry*; D012015:Reference Standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014801:Vitamin A / Q000737:chemistry*; D014815:Vitamins / Q000737:chemistry*
D014815:Vitamins; D014801:Vitamin A