A simple method for the synthesis of hyaluronic acid coated magnetic nanoparticles for highly efficient cell labelling and in vivo imaging.
Highly stable colloidal hyaluronic acid coated magnetic nano-particles were prepared via a ligand exchange method. These particles exhibited excellent cell labeling efficiencies and superior potential as MRI contrast agents, which are useful to target tumor cells expressing hyaluronic acid receptors such as CD44.
Department of Chemistry, Michigan State University, East Lansing, Michigan, 48824, USA.
Mohammad H
MH
El-Dakdouki
Kheireddine
K
El-Boubbou
David C
DC
Zhu
Xuefei
X
Huang