Chlorhexidine-associated transient hyperchloremia in an infant.
An infant was cleansed with 2% clorhexidine gluconate (CHG) because of repeated sepsis episodes from skin colonization. Asymptomatic hyperchloremia ensued, most likely associated with CHG therapy. Fourty-eight hours after CHG therapy withdrawal, serum chloride levels returned to normal. Hyperchloremia may be a reversible adverse effect of extensive use of CHG.
Division of Neonatology, Zekai Tahir Burak Maternity Teaching Hospital, Cebeci, Ankara, TurkeyDepartment of Pediatrics, Division of Neonatology, Yildirim Beyazit University, Ankara, Turkey.
Istemi Han
IH
Celik
Serife Suna
SS
Oguz
Ugur
U
Dilmen
D000891:Anti-Infective Agents, Local / Q000009:adverse effects*; D002710:Chlorhexidine / Q000009:adverse effects / Q000031:analogs & derivatives*; D002713:Chlorine / Q000097:blood*; D003872:Dermatitis / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007223:Infant; D007230:Infant, Low Birth Weight; D018805:Sepsis / Q000188:drug therapy* / Q000209:etiology; D012867:Skin / Q000378:metabolism
D000891:Anti-Infective Agents, Local; D002713:Chlorine; C010882:chlorhexidine gluconate; D002710:Chlorhexidine