Nanophthalmos: quantitative analysis of anterior chamber angle configuration before and after cataract surgery.
OBJECTIVE
To analyse quantitatively the anterior segment configuration in eyes with nanophthalmos before and after cataract surgery.


METHODS
This was a retrospective, non-comparative, interventional case series. Eleven eyes in eight patients with nanophthalmos who underwent phacoemulsification and intraocular lens implantation were identified from the department's surgical log, and their clinical records were retrospectively reviewed. Main outcome measures were as follows: visual acuity, intraocular pressure (IOP), axial length and the following ultrasound biomicroscopy parameters: angle opening distance at 500 μm anterior to the scleral spur (AOD500), trabecular-iris angle (TIA) and trabecular ciliary process distance.


RESULTS
The mean axial length of the eyes was 17.3 ± 1.7 mm. AOD500 and TIA increased after cataract surgery (p<0.005). Smaller axial length, AOD500 and TIA before cataract surgery were observed in eyes with preoperative IOP elevation than those without preoperative IOP elevation (p<0.05). Lower postoperative IOP was correlated with greater AOD500 and TIA before cataract surgery (p<0.05).


CONCLUSIONS
Cataract surgery deepened the anterior chamber and widened the anterior chamber angle in nanophthalmic eyes. Cataract surgery may have beneficial effects on IOP in eyes with nanophthalmos.
Department of Ophthalmology, Division of Ophthalmology and Visual Science, Graduated School of Medical and Dental Sciences, Niigata University, Niigata, Japan. masaaki.seki@gmail.com
Masaaki
M
Seki
Takeo
T
Fukuchi
Jun
J
Ueda
Kieko
K
Suda
Tomoko
T
Nakatsue
Yoko
Y
Tanaka
Tetsuya
T
Togano
Susumu
S
Yamamoto
Hiroaki
H
Hara
Haruki
H
Abe
D000328:Adult; D000368:Aged; D000867:Anterior Chamber / Q000000981:diagnostic imaging*; D058452:Axial Length, Eye / Q000473:pathology; D002924:Ciliary Body / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D007498:Iris / Q000000981:diagnostic imaging*; D019654:Lens Implantation, Intraocular; D008297:Male; D008850:Microphthalmos / Q000601:surgery*; D033401:Microscopy, Acoustic; D008875:Middle Aged; D018918:Phacoemulsification; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology