Palladium-catalyzed vicinal difunctionalization of internal alkenes: diastereoselective synthesis of diamines.
Internal affairs: the first general palladium-catalyzed intermolecular diamination of internal alkenes employs different nitrogen sources, which add to the alkene in a regio- and diastereoselective fashion. The resulting diamination products can be converted directly into a known ligand motif.
Institute of Chemical Research of Catalonia, Tarragona, Spain.
Claudio
C
Martínez
Kilian
K
Muñiz