Understanding metabolic alterations in cancer cells: a promising new/old approach to eradicate cancer.
Alterations in several aspects of cell metabolism have recently been re-discovered as one of the main features of most cancer cells. The three minireviews discuss how alterations in the glycolytic pathway, in lipid metabolism and in amino acid sensing may give a growth advantage to cells with high proliferative rates, experiencing inadequate nutrients availability.
Institute of Genetics and Biophysics-CNR, Naples, Italy.
Ingram
I
Iaccarino
D000255:Adenosine Triphosphate / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D006801:Humans; D050356:Lipid Metabolism; D009369:Neoplasms / Q000378:metabolism* / Q000628:therapy; D009711:Nucleotides / Q000378:metabolism; D010085:Oxidative Phosphorylation
D000596:Amino Acids; D009711:Nucleotides; D000255:Adenosine Triphosphate