[Stereotactic radiotherapy for intracranial meningioma].
Meningiomas are the most common non-malignant tumours of the brain. Gross-total resection remains the preferred treatment, if achievable without morbidity. Radiation therapy is advocated for inoperable, incompletely resected, or recurrent grade 1 tumours, if there is a progressive, symptomatic lesion, or in case of functional impairment. Postoperative radiation therapy is recommended for grade 2 or 3 lesions. Fractionated stereotactic radiotherapy and stereotactic radiosurgery are high precision techniques, allowing good sparing of surrounding tissues. Fractionated stereotactic radiotherapy and stereotactic radiosurgery give comparable results, with excellent 5-year tumour control rates of more than 90% for benign meningiomas. Toxicity is low and seems equivalent, despite a biased use of fractionated stereotactic radiotherapy for larger meningiomas, close to critical structures. Fractionated stereotactic radiotherapy seems to be of special interest in the treatment of cavernous sinus or optic pathways meningiomas. The different therapeutic modalities should be discussed by a multidisciplinary team.
Service de radiothérapie, institut Claudius-Regaud, 20-24 rue du Pont-Saint-Pierre, Toulouse cedex, France.
M
M
Delannes
J-P
JP
Maire
J
J
Sabatier
F
F
Thillays
D002426:Cavernous Sinus; D019583:Dose Fractionation, Radiation; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000473:pathology / Q000601:surgery*; D008579:Meningioma / Q000473:pathology / Q000601:surgery*; D019574:Optic Nerve Neoplasms / Q000473:pathology / Q000601:surgery; D016634:Radiosurgery; D011880:Radiotherapy Planning, Computer-Assisted; D019043:Vascular Neoplasms / Q000473:pathology / Q000601:surgery