[Influence of nanosize particles of cobalt ferrite on contractile responses of smooth muscle segment of airways].
Contractile responses of airways segments of porpoises inhaling nanopowder CoFe2O4 were stidued by means of a mechanographic method. Inhalation of the nanosize particles of CoFe2O4 in vivo and in vitro testing the nanomaterial on isolated smooth muscles led to potentiation histaminergic, cholinergic contractile activity in airways of porpoises and to strengthening of adrenergic relaxing answers. Nanosize particles vary amplitude of hyperpotassium reductions in smooth muscle segments of airways similarly to the effect of depolymerizing drug colchicine.
L V
LV
Kapilevich
T N
TN
Zaĭtseva
A V
AV
Nosarev
E Iu
EIu
D'iakova
Z R
ZR
Petlina
L M
LM
Ogorodova
B G
BG
Ageev
A A
AA
Magaeva
V I
VI
Itin
O G
OG
Terekhova
M A
MA
Medvedev
D000818:Animals; D001980:Bronchi / Q000187:drug effects; D003035:Cobalt / Q000009:adverse effects* / Q000494:pharmacology; D005290:Ferric Compounds / Q000009:adverse effects* / Q000494:pharmacology; D006168:Guinea Pigs; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects* / Q000502:physiology; D009130:Muscle, Smooth / Q000187:drug effects* / Q000502:physiology; D053758:Nanoparticles / Q000008:administration & dosage / Q000009:adverse effects*; D014132:Trachea / Q000187:drug effects / Q000502:physiology
D005290:Ferric Compounds; C001215:ferrite; D003035:Cobalt