Diffuse type gastric carcinoma presenting as giant gastric folds: lessons learned from six miss diagnosed cases.
Hyperplastic gastropathy is a rare condition characterized by giant gastric folds. There are numerous causes of giant gastric folds included benign diseases (Menetrier's disease, pseudolymphoma and lymphocytic gastritis) and malignant diseases (gastric carcinoma, lymphoma and Zollinger-Ellison syndrome). Six gastric carcinoma presenting as giant gastric folds were described. Lessons learned from six miss diagnosed cases and how to improve the accuracy of diagnosis were elucidated. Moreover, we propose a hypothesis that in diffuse type gastric carcinoma gastric cancer, which manifested with thickness of gastric folds, there must be some media which is released by cancer cells to stimulate superficial mucosa layer benign cells proliferation, instead of malignant cells infiltrating directly.
Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University medical school, Hangzhou, 310016, PR China.
Mei
M
Mei
Ni
N
Jingmei
Chen
C
Zongming
Jin
J
Mei
Sun
S
Leimin
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000473:pathology*; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology*