Multiphase enantioselective Kharasch-Sosnovsky allylic oxidation based on neoteric solvents and copper complexes of ditopic ligands.
Recoverable multiphase enantioselective catalytic systems for the Kharasch-Sosnovsky oxidation of cycloalkenes with tert-butyl peroxybenzoate are described, based on the use of [BMIM][PF(6)] and a new solvent derived from glycerol as the catalyst reservoir phases, and chiral copper complexes with different ligands from the bis(oxazoline) family. The best results are obtained with the glycerol-derived solvent and a recently described azabisoxazoline-based ditopic ligand, allowing up to four uses of the catalytic phase with good results.
Instituto de Síntesis Química y Catálisis Homogénea, CSIC-Univ. de Zaragoza, Calle Pedro Cerbuna, 12. E-50009 Zaragoza, Spain.
Luis
L
Aldea
José I
JI
García
José A
JA
Mayoral