Effect of triazine derivative added to denture materials on a microcosm biofilm model.
The aim of this study was to assess the effect of triazine incorporation to denture materials on biofilm formation of saliva derived from microcosms of patients who are positive for Candida albicans. Biofilms were formed on microwave-cured acrylic resin, one hard denture liner, and two soft denture liners containing 0, 2.5, 5, and 10% triazine. For experimental subset (n = 10), mechanical properties of the materials and colony-forming unit counts from the biofilms formed on the materials were assessed. Flexural strength and modulus decreased with the addition of 2.5% triazine (p < 0.01). In general, the addition of 5 and 10% triazine leaded to more soluble materials (p < 0.001). Saliva donor with candidiasis resulted in higher counts of total microorganisms (p = 0.0294) and Streptococci (p = 0.0008). Soft denture liners showed the highest counts for total microorganisms, Streptococci, and Candida species (p < 0.001). The addition of triazine directly to denture materials was not beneficial in reducing biofilm formation in a complex biofilm model.
Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Aline Pinheiro
AP
de Moraes
Caroline Konzgen
CK
Barwaldt
Thaís Zorzoli
TZ
Nunes
Rafael
R
Sarkis-Onofre
Fabrício Aulo
FA
Ogliari
Noéli
N
Boscato
Tatiana
T
Pereira-Cenci
D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development; D002176:Candida albicans / Q000502:physiology*; D002177:Candidiasis / Q000382:microbiology; D003764:Dental Materials / Q000494:pharmacology*; D006801:Humans; D012463:Saliva / Q000382:microbiology*; D013291:Streptococcus / Q000502:physiology*; D014227:Triazines / Q000494:pharmacology*
D003764:Dental Materials; D014227:Triazines