Gametogenesis in a dish.
Recent progress in the induced pluripotent stem cell (iPSC) field as well as the establishment of germline stem cell isolation and culture methodologies may provide an in vitro platform for the study of physiological and pathological human gamete development and open new avenues for cell replacement-based personalized treatment of infertility.
Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Ying
Y
Gu
Guang-Hui
GH
Liu
Juan Carlos
JC
Izpisua Belmonte
D053595:Embryonic Stem Cells / Q000166:cytology; D005260:Female; D005718:Gametogenesis / Q000502:physiology*; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology* / Q000637:transplantation; D007246:Infertility / Q000628:therapy; D008297:Male; D008954:Models, Biological