Hemoproteins in dissimilatory sulfate- and sulfur-reducing prokaryotes.
Dissimilatory sulfate and sulfur reduction evolved billions of years ago and while the bacteria and archaea that use this unique metabolism employ a variety of electron donors, H(2) is most commonly used as the energy source. These prokaryotes use multiheme c-type proteins to shuttle electrons from electron donors, and electron transport complexes presumed to contain b-type hemoproteins contribute to proton charging of the membrane. Numerous sulfate and sulfur reducers use an alternate pathway for heme synthesis and, frequently, uniquely specific axial ligands are used to secure c-type heme to the protein. This review presents some of the types and functional activities of hemoproteins involved in these two dissimilatory reduction pathways.
Laboratoire de Microbiologie IRD, UMR 180, Universités de Provence et de la Méditerranée, ESIL-GBMA, Case 925, Marseille Cedex 09, France.
Guy D
GD
Fauque
Larry L
LL
Barton
D001419:Bacteria / Q000201:enzymology* / Q000235:genetics / Q000378:metabolism; D004734:Energy Metabolism; D006420:Hemeproteins / Q000235:genetics / Q000378:metabolism*; D006859:Hydrogen / Q000378:metabolism; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000235:genetics / Q000378:metabolism*; D013431:Sulfates / Q000378:metabolism*; D013455:Sulfur / Q000378:metabolism*
D006420:Hemeproteins; D013431:Sulfates; D013455:Sulfur; D006859:Hydrogen; D010088:Oxidoreductases