Archaeal tetrathionate hydrolase goes viral: secretion of a sulfur metabolism enzyme in the form of virus-like particles.
In the course of screening for virus-host systems in extreme thermal environments, we have isolated a strain of the hyperthermophilic archaeaon Acidianus hospitalis producing unusual filamentous particles with a zipper-like appearance. The particles were shown to represent a secreted form of a genuine cellular enzyme, tetrathionate hydrolase, involved in sulfur metabolism.
Institut Pasteur, Department of Microbiology, Molecular Biology of the Gene in Extremophiles Unit, Paris, France.
Mart
M
Krupovic
Nuno
N
Peixeiro
Marcus
M
Bettstetter
Reinhard
R
Rachel
David
D
Prangishvili
D041541:Acidianus / Q000201:enzymology*; D019281:Dimerization; D004591:Electrophoresis, Polyacrylamide Gel; D006867:Hydrolases / Q000737:chemistry* / Q000302:isolation & purification / Q000648:ultrastructure; D008854:Microscopy, Electron; D016685:Mitomycin; D008958:Models, Molecular; D046912:Multiprotein Complexes / Q000737:chemistry* / Q000302:isolation & purification / Q000648:ultrastructure; D011487:Protein Conformation
D046912:Multiprotein Complexes; D016685:Mitomycin; D006867:Hydrolases; C104756:tetrathionate hydrolase