Post-treatment change in the localization of recurrent or persistent macular edema secondary to branch retinal vein occlusion.
OBJECTIVE
To investigate the change in localization of recurrent or persistent macular edema (ME) secondary to branch retinal vein occlusion (BRVO) after a therapeutic intervention.


METHODS
Twenty-six eyes of 23 patients with recurrent or persistent ME secondary to BRVO were included in this retrospective case series. We analyzed the distance between the fovea and the top of the ME (fovea-ME top distance) and the ME area using optical coherence tomography before treatment and when ME recurred or persisted.


RESULTS
The fovea-ME top distance decreased from 1.8 ± 1.6 to 1.2 ± 1.3 mm (p = 0.008). The ME area also decreased from 11.9 ± 4.9 to 7.6 ± 5.0 mm(2) (p = 0.0003). The retinal vascular leakage area correlated with the ME area in all eyes.


CONCLUSIONS
The site of recurrent or persistent ME tends to shift toward the fovea. These results suggest that residual perifoveal vascular leakage might be the predominant cause of recurrent or persistent ME.
Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Mitsuru
M
Arima
Masanori
M
Miyazaki
Satoshi
S
Arakawa
Yasutaka
Y
Mochizuki
Tatsuro
T
Ishibashi
D000368:Aged; D001485:Basement Membrane / Q000601:surgery; D005260:Female; D005584:Fovea Centralis; D006801:Humans; D007202:Indicators and Reagents; D008269:Macular Edema / Q000175:diagnosis* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012170:Retinal Vein Occlusion / Q000150:complications* / Q000601:surgery; D012189:Retrospective Studies; D012394:Rosaniline Dyes; D041623:Tomography, Optical Coherence; D014821:Vitrectomy
D007202:Indicators and Reagents; D012394:Rosaniline Dyes; C004692:coomassie Brilliant Blue