Evaluation of cardiac involvement with mediastinal lymphoma: the role of innovative integrated cardiovascular imaging.
A 73-year-old woman presented in right heart failure. Computed tomography of the chest revealed a 3 cm × 5 cm anterior mediastinal mass. Contrast-enhanced two-dimensional transthoracic echocardiography, cardiac magnetic resonance imaging (MRI), positron emission tomography (PET), and MRI-PET fusion demonstrated invasion of the pericardium and right heart by the tumor. Mediastinal biopsy revealed high-grade diffuse large B-cell lymphoma, which responded to chemotherapy. The role of each modality in this case was discussed in the manuscript. In conclusion, the integration of multiple imaging modalities is extremely useful in the characterization, localization, diagnosis and treatment of an unusual cardiac mass.
Department of Medicine, Division of Cardiology Department of Radiology, Stony Brook University Medical Center, Stony Brook, New York 11794, USA.
Mark
M
Goldman
Robert
R
Matthews
Hong
H
Meng
Thomas
T
Bilfinger
Smadar
S
Kort
D000368:Aged; D004452:Echocardiography; D005260:Female; D006338:Heart Neoplasms / Q000175:diagnosis*; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis*; D019028:Magnetic Resonance Imaging, Cine; D008479:Mediastinal Neoplasms / Q000175:diagnosis*; D049268:Positron-Emission Tomography; D013382:Subtraction Technique