No amygdala attenuation in schizophrenic patients treated with atypical antipsychotics.
Functional magnetic resonance (fMRI) imaging was used to measure amygdala activation in an emotional valence discrimination task in clinically stable patients with schizophrenia treated with atypical antipsychotics and healthy controls. No difference was detected between patients with schizophrenia and controls.
Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria. gabriele.sachs@meduniwien.ac.at
Gabriele
G
Sachs
Ewald
E
Moser
Heinz
H
Katschnig
Ruben C
RC
Gur
Raquel E
RE
Gur
Andreas
A
Erfurth
D000328:Adult; D000679:Amygdala / Q000098:blood supply / Q000187:drug effects*; D000704:Analysis of Variance; D014150:Antipsychotic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001931:Brain Mapping; D017352:Echo-Planar Imaging; D004644:Emotions / Q000187:drug effects; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D010100:Oxygen / Q000097:blood; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000188:drug therapy / Q000473:pathology* / Q000503:physiopathology; D055815:Young Adult
D014150:Antipsychotic Agents; D010100:Oxygen