Difficult to control asthma in the patient with pseudoachondroplasia.
Pseudoachondroplasia (PsA) is a type of short-limbed dwarfism resulting from mutations in the cartilage oligomeric matrix protein gene. Skeletal involvement in the PsA is well-described but there are not any published cases reporting airways involvement. The authors present a case of a female with the PsA and congenital anomalies of the respiratory tract resulting in the tracheobronchomalacia and a difficult to control asthma.
Respiratory Medicine Department, Prince Philip Hospital, LLanelli, UK. mwilczynska@doctors.org.uk
Maria
M
Wilczynska
Teresa
T
Ching
D000130:Achondroplasia / Q000150:complications*; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D058666:Adrenergic beta-2 Receptor Agonists / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents; D001249:Asthma / Q000150:complications* / Q000188:drug therapy*; D017963:Azithromycin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D011651:Pulmonary Artery / Q000002:abnormalities; D055089:Tracheobronchomalacia / Q000150:complications*
D000305:Adrenal Cortex Hormones; D058666:Adrenergic beta-2 Receptor Agonists; D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D017963:Azithromycin; D011239:Prednisolone