Localized mandibular enlargement in end-stage renal disease: two case reports and a review of the literature.
Enlargement of the jaws is an infrequently reported complication of chronic kidney disease mineral and bone disorder (CKD-MBD). Two cases of localized mandibular swellings in young patients with histories of end-stage renal disease are discussed with a review of the literature. Although 17 of the first 19 cases that were reported exhibited diffuse enlargement, these reports increase the number of localized swellings to 8 and support the contention that localized expansion of the jaws as a manifestation of CKD-MBD is more common than originally recognized.
Harvard School of Dental Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02120, USA. mark_lerman@hms.harvard.edu
Mark A
MA
Lerman
Catherine
C
Do
Lakshman
L
Gunaratnam
Cyelee
C
Kulkarni
Kevin
K
Tucker
Sook-Bin
SB
Woo
D000328:Adult; D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000150:complications / Q000209:etiology / Q000601:surgery; D006984:Hypertrophy / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D008336:Mandibular Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D055815:Young Adult