Fluorinated graphene for promoting neuro-induction of stem cells.
Surface engineering of substrates offers the possibility of controlling the physiological functions of cells at the molecular level. Fluorinated graphene promotes the differentiation of MSCs towards neuronal lineages. Cell alignment using printed polydimethylsiloxane channel arrays on fluorinated graphene further enhances the neuro-induction of MSCs even in the absence of chemical inducers.
Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore.
Yu
Y
Wang
Wong Cheng
WC
Lee
Kiran Kumar
KK
Manga
Priscilla Kailian
PK
Ang
Jiong
J
Lu
Yan Peng
YP
Liu
Chwee Teck
CT
Lim
Kian Ping
KP
Loh
D002454:Cell Differentiation; D002478:Cells, Cultured; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D054879:Halogenation; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D009474:Neurons / Q000166:cytology; D013499:Surface Properties; D023822:Tissue Engineering
D004129:Dimethylpolysiloxanes; C013830:baysilon; D006108:Graphite