Noninvasive prenatal diagnostics by maternal plasma DNA sequencing.
This article evaluates the recent publication by Palomaki et al. that confirms at a large scale in a clinical setting previous data that massively parallel sequencing of cell-free DNA isolated from maternal plasma can effectively identify trisomy 18 and trisomy 13, as well as Down syndrome (trisomy 21).
VU University Medical Center, De Boelelaan 1117, 1081H Amsterdam, The Netherlands.  cbm.oudejans@vumc.nl.
Cees B
CB
Oudejans