"Embryo glue" does not seem to improve chances of subsequent pregnancy in refractory in vitro fertilization cases.
OBJECTIVE
To determine if the use of Embryo glue improves implantation and pregnancy rates following embryo transfer (ET) in women who failed to conceive in three previous attempts.


METHODS
A matched controlled study was performed in women undergoing IVF-ET, donor oocyte recipients and women using their own oocytes having fresh or frozen ETs. A woman having Embryo glue was matched with the very next woman not using glue within six months of age and having the same number of previous failed ETs.


RESULTS
Embryo glue did not seem to improve pregnancy or implantation rates. In fact, in evaluating fresh embryo transfers there was a significantly higher live delivered pregnancy rate in the women not using Embryo glue (39.3%) vs those using the glue (14.3%).


CONCLUSIONS
Embryo glue does not improve pregnancy outcome in women failing in previous IVF cycles.
The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA. laurie@ccivf.com
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D000328:Adult; D010064:Embryo Implantation / Q000187:drug effects*; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid; D011247:Pregnancy; D018873:Pregnancy Rate
C573452:Embryo glue; D006820:Hyaluronic Acid