Long-term successful percutaneous coronary intervention in factor VII deficiency.
Factor VII deficiency (FVIId) is a congenital coagulation disorder with a wide spectrum of bleeding phenotypes. Percutaneous coronary intervention requires full anticoagulation during stent implantation to avoid acute coronary thrombosis and long-term dual antiplatelet therapy. Feasibility of percutaneous coronary intervention in FVIId is not described in literature. We present a successful case of percutaneous coronary intervention in a 55-year-old male with FVIId, discussing briefly the periprocedural handicaps (anticoagulation regimen and hemostasis at arterial puncture site) as the safety of long-term antiplatelet therapy, and future implications for recombinant FVIId administration in a patient with a previous coronary stent.
Interventional Cardiology Unit, Cardiology Department, Clinic Universitary Hospital Lozano Blesa, Zaragoza, Spain. joselinares1979@hotmail.com
Jose Antonio
JA
Linares Vicente
Jorge Ondiviela
JO
Pérez
Rosa Cornudella
RC
Lacasa
D000787:Angina Pectoris / Q000150:complications / Q000000981:diagnostic imaging; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D001241:Aspirin / Q000008:administration & dosage; D000077144:Clopidogrel; D023921:Coronary Stenosis / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000175:diagnosis; D005168:Factor VII Deficiency / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications / Q000175:diagnosis; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*; D011859:Radiography; D018570:Risk Assessment; D015607:Stents; D013923:Thromboembolism / Q000517:prevention & control; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D013997:Time Factors; D016896:Treatment Outcome
D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine; D001241:Aspirin