α/γ(4)-Hybrid peptide helices: synthesis, crystal conformations and analogy with the α-helix.
Synthesis, crystal conformations of α/γ(4)-hybrid peptide helices containing proteinogenic amino acid side-chains, and the analogy with the α-helix are reported. Results suggest that α/γ(4)-hybrid peptides adopted helical conformations with 12-membered H-bond pseudocycles in single crystals.
Department of Chemistry, Indian Institute of Science Education and Research, Dr Homi Bhabha Road, Pashan, Pune-411021, India.
Anupam
A
Bandyopadhyay
Sandip V
SV
Jadhav
Hosahudya N
HN
Gopi
D000596:Amino Acids / Q000737:chemistry; D002942:Circular Dichroism; D003460:Crystallization; D008958:Models, Molecular; D010455:Peptides / Q000138:chemical synthesis / Q000737:chemistry*; D017433:Protein Structure, Secondary
D000596:Amino Acids; D010455:Peptides