PCDD/PCDF, dl-PCB and PBDE serum levels of Slovak general population.
Blood serum specimens from 81 non-occupationally exposed adults residing in four areas close to municipal and waste incinerators as well as metallurgical industry plant and 44 adult subjects coming from control area of Slovakia were analysed for polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), dioxin-like polychlorinated biphenyls (dl-PCBs) and polybrominated diphenylethers (PBDEs). The concentration of total WHO(98)TEQ PCDD/F/dl-PCBs in whole group of donors from areas where known sources causing dioxin contamination are present was significantly higher than in control group of donors (p<0.001). Correlation between the age of donors and PCDD/F and dl-PCB levels was confirmed (Spearman's r(PCDD/Fs)=0.543, r(dl-PCBs)=0.521, p<0.001). Furthermore, this study presents first results concerning the PBDE congeners in human serum of Slovak general population. The total concentration (congeners 28, 47, 99, 100, 153, 154, 183) in control group was approximately 1.5-times higher in comparison to that of residents coming from areas with supposed environmental pollution. The most abundant congeners in all samples were BDE-47 and BDE-153 with median values of 0.24 ng g(-1) lipid and 0.23ngg(-1) lipid, respectively. The positive association between PBDE values and age of donors was not found.
Department of Toxic Organic Pollutants, Slovak Medical University, Limbová 12, 833 03 Bratislava, Slovak Republic. jana.chovancova@szu.sk
Jana
J
Chovancová
Kamil
K
Conka
Anna
A
Fabišiková
Zuzana Stachová
ZS
Sejáková
Milena
M
Dömötörová
Beáta
B
Drobná
Soňa
S
Wimmerová
D000328:Adult; D000368:Aged; D001572:Benzofurans / Q000097:blood*; D000072338:Dibenzofurans, Polychlorinated; D005260:Female; D055768:Halogenated Diphenyl Ethers / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011078:Polychlorinated Biphenyls / Q000097:blood*; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000097:blood; D018154:Slovakia; D055815:Young Adult
D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D055768:Halogenated Diphenyl Ethers; D000072317:Polychlorinated Dibenzodioxins; D011078:Polychlorinated Biphenyls