[A case of primary urotherial carcinoma with glandular differentiation of the renal pelvis with high serum level of carbohydrate antigen 19-9 (CA19-9)].
A 63-year-old man visited our hospital with body weight loss. Laboratory examination revealed a high serum level of carbohydrate antigen 19-9 (CA19-9) and LDH. There were no abnormal findings in the gastrointestinal tract. Enhanced abdominal computed tomography (CT) revealed a renal tumor, 5×3 cm in diameter, in the right lower pole and multiple lymph node swelling. The right renal tumor was not a typical renal cell carcinoma, so we considered the presence of bellini duct carcinoma and renal pelvis carcinoma, we performed right nephroureterectomy. Histopathological diagnosis was urothelial carcinoma with glandular differentiation of the renal pelvis. Post operation chemotherapy with GC (gemcitabine/cisplatin: 3-cycle), MVAC (methotrexate/vinblastine/doxorubicin/cisplatin: 1-cycle), TS-1 + CBDCA (tegafur-gimeracil-oteracil potassium/carboplatin: 3-cycle) was performed for lymph node metastasis, but he died of cachexia 18 months after operation.
The Department of Urology, Kinki University School of Medicine.
Yoshitaka
Y
Itami
Nobutaka
N
Shimizu
Taiji
T
Hayashi
Yasuharu
Y
Nagai
Yasuyuki
Y
Kobayashi
Yutaka
Y
Yamamoto
Takafumi
T
Minami
Masahiro
M
Nozawa
Kazuhiro
K
Yoshimura
Tokumi
T
Ishii
Hirotsugu
H
Uemura
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018395:CA-19-9 Antigen / Q000097:blood*; D002277:Carcinoma / Q000097:blood / Q000188:drug therapy / Q000473:pathology*; D002945:Cisplatin / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D006801:Humans; D007680:Kidney Neoplasms / Q000097:blood / Q000188:drug therapy / Q000473:pathology*; D007682:Kidney Pelvis / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D019459:Urothelium / Q000473:pathology; D014747:Vinblastine / Q000627:therapeutic use
D018395:CA-19-9 Antigen; D014747:Vinblastine; D004317:Doxorubicin; D002945:Cisplatin; D008727:Methotrexate