Approximate entropy of network parameters.
We study the notion of approximate entropy within the framework of network theory. Approximate entropy is an uncertainty measure originally proposed in the context of dynamical systems and time series. We first define a purely structural entropy obtained by computing the approximate entropy of the so-called slide sequence. This is a surrogate of the degree sequence and it is suggested by the frequency partition of a graph. We examine this quantity for standard scale-free and Erdös-Rényi networks. By using classical results of Pincus, we show that our entropy measure often converges with network size to a certain binary Shannon entropy. As a second step, with specific attention to networks generated by dynamical processes, we investigate approximate entropy of horizontal visibility graphs. Visibility graphs allow us to naturally associate with a network the notion of temporal correlations, therefore providing the measure a dynamical garment. We show that approximate entropy distinguishes visibility graphs generated by processes with different complexity. The result probes to a greater extent these networks for the study of dynamical systems. Applications to certain biological data arising in cancer genomics are finally considered in the light of both approaches.
Statistical Cancer Genomics, UCL Cancer Institute and Department of Physics & Astronomy, University College London, London, UK. jawest@gmail.com
James
J
West
Lucas
L
Lacasa
Simone
S
Severini
Andrew
A
Teschendorff
D000465:Algorithms; D001703:Biophysics / Q000379:methods*; D001943:Breast Neoplasms / Q000235:genetics* / Q000378:metabolism*; D016208:Databases, Factual; D019277:Entropy; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D023281:Genomics; D006801:Humans; D009362:Neoplasm Metastasis; D017711:Nonlinear Dynamics; D016012:Poisson Distribution; D015203:Reproducibility of Results