Photocontrolled binding and binding-controlled photochromism within anthracene-modified DNA.
Modified DNA strands undergo a reversible light-induced reaction involving the intramolecular photodimerization of two appended anthracene tags. The photodimers exhibit markedly different binding behavior toward a complementary strand that depends on the number of bases between the modified positions. By preforming the duplex, photochromism can be suppressed, illustrating dual-mode gated behavior.
School of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Jack
J
Manchester
Dario M
DM
Bassani
Jean-Louis H A
JL
Duprey
Luciana
L
Giordano
Joseph S
JS
Vyle
Zheng-yun
ZY
Zhao
James H R
JH
Tucker
D000873:Anthracenes / Q000737:chemistry* / Q000528:radiation effects; D001483:Base Sequence; D004247:DNA / Q000737:chemistry / Q000528:radiation effects*; D008027:Light
D000873:Anthracenes; D004247:DNA; C034020:anthracene