Epithelial homeostasis: elimination by live cell extrusion.
To maintain a functional and harmonious epithelial society, the number and quality of cells need to be tightly controlled. Two recent studies reveal a novel cellular process for epithelial homeostasis: crowding-mediated live cell extrusion.
Division of Molecular Oncology, Institute for Genetic Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.
Hiroto
H
Katoh
Yasuyuki
Y
Fujita
D000818:Animals; D002452:Cell Count; D048708:Cell Growth Processes; D004847:Epithelial Cells / Q000502:physiology*; D004848:Epithelium / Q000502:physiology*; D006706:Homeostasis