Multidirectional cobalt-catalyzed Diels-Alder/1,4-hydrovinylation sequences.
The combination of two powerful cobalt-catalyzed carbon-carbon bond forming transformations, namely, the Diels-Alder and the 1,4-hydrovinylation reaction, in a tandem or a sequential one-pot procedure, opened up a concise and efficient route to polysubstituted aromatic systems and cyclohex-3-enone derivatives. Furthermore, ozonolysis of the latter products led to polycarbonyl compounds with tailored carbonyl group distances which could be characterized via their respective BF(2)-borinane complexes. The cobalt catalysts tolerated several functional groups, and a flexible approach to polyfunctionalized compounds in concise fashion was described.
Fachbereich Chemie, Philipps-Universität Marburg, Hans-Meerwein-Str. 35043 Marburg, Germany.
Florian
F
Erver
Julian R
JR
Kuttner
Gerhard
G
Hilt