[Induction of the NO synthesis in lactobacilli under stress conditions].
An increase in the nitric oxide (NO) biosynthesis in Lactobacillus plantarum 8P-A3 cells takes place under strong stress influence, which leads to a considerable decrease in the microbial cell viability: heating at 70 degrees C and 80 degrees C, prolonged cultivation, toxic effect of hexylresorcinol. The factors, which do not lead to cell death, such as heating at 60 degrees C, 50 microg/ml homoserine lactone, Bacillus intermedius 7P ribonuclease (binase) in concentrations up to 300 microg/ml, do not induce NO synthesis. The activation of the NO biosynthesis in response to stress treatment evidences to universality of key-mechanisms of stress response in cells differing in the level of their organization as well as to important role of nitric oxide in them.
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Smolentseva
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Iarullina
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Il'inskaia
D015107:4-Butyrolactone / Q000008:administration & dosage; D002470:Cell Survival / Q000187:drug effects*; D004722:Endoribonucleases / Q000008:administration & dosage; D004789:Enzyme Activation / Q000187:drug effects; D006604:Hexylresorcinol / Q000008:administration & dosage; D048191:Lactiplantibacillus plantarum / Q000378:metabolism*; D009569:Nitric Oxide / Q000096:biosynthesis* / Q000378:metabolism*; D019001:Nitric Oxide Synthase / Q000378:metabolism; D013312:Stress, Physiological; D013696:Temperature
D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D004722:Endoribonucleases; C022543:ribonuclease T(2); D015107:4-Butyrolactone; D006604:Hexylresorcinol