Atypical tumour-like involvement of the colon in Henoch-Schonlein purpura successfully treated with the administration of factor XIII.
Henoch-Schönlein purpura (HSP) is a type of systemic vasculitis of the small vessels, which frequently involves the skin, kidney and gastrointestinal tract. While the typical intestinal features of HSP include diffuse mucosal redness, small ring-like petechiae and haemorrhagic erosions, tumour-like lesions are rarely observed. The current study presents a rare case of HSP with an intestinal tumour-like lesion in the caecum. The intestinal lesion caused fresh melaena, and was completely resolved with the administration of factor XIII as described in previously reported cases. It is important to immediately undergo proper treatment for improving tumour-like lesions which may cause severe complications, such as excessive haemorrhage and stricture.
Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Japan.
Katuyoshi
K
Ando
Mikihiro
M
Fujiya
Ryuji
R
Sugiyama
Toshie
T
Nata
Yoshiki
Y
Nomura
Nobuhiro
N
Ueno
Shin
S
Kashima
Chisato
C
Ishikawa
Yuhei
Y
Inaba
Takahiro
T
Ito
Kentaro
K
Moriichi
Kotaro
K
Okamoto
Katsuya
K
Ikuta
Jiro
J
Watari
Yusuke
Y
Mizukami
Yutaka
Y
Kohgo
D003108:Colonic Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003110:Colonic Neoplasms / Q000175:diagnosis; D003937:Diagnosis, Differential; D016099:Endoscopy, Gastrointestinal; D005176:Factor XIII / Q000627:therapeutic use*; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D055815:Young Adult
D005176:Factor XIII