Comparison of central corneal thickness measurements by ultrasound pachymeter, optical coherence tomography and corneal topography.
OBJECTIVE
To compare central corneal thickness (CCT) measured by standard ultrasound pachymeter with optical coherence tomography (OCT) and corneal topography


METHODS
A cross-sectional study of central corneal thickness measurement by ultrasound pachymeter, OCT and corneal topography in 30 eyes of 30 healthy volunteers was done by a single examiner at Thammasat University Hospital between October 2010 and January 2011. The results were compared using ANOVA for repeated measures and Pearson correlation.


RESULTS
Mean central corneal thickness by ultrasound pachymeter OCT and corneal topography were 552.1 +/- 33.6 microm, 554.5 +/- 33.0 microm and 552.8 +/- 39.0 microm respectively. There were no statistically significant differences in the measurement results among the three modalities (p = 0.718). There was a significant linear correlation between OCT and ultrasound pachymeter (Pearson correlation = 0.985, p < 0.001), corneal topography and ultrasound pachymeter (Pearson correlation = 0.965, p < 0.001) and corneal topography and OCT (Pearson correlation = 0.965, p < 0.001).


CONCLUSIONS
Mean central corneal thickness among ultrasonic pachymeter, OCT and corneal topography were comparable and had significant linear correlations. In clinical practice, these three modalities could be interchangeable.
Department of Ophthalmology, H.M. Queen Sirikit Hospital, Cholburi, Thailand. jsv2010@live.com
Phanvipha
P
Pholshivin
Wimolwan
W
Tangpagasit
D000328:Adult; D003315:Cornea / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D019781:Corneal Topography; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D011859:Radiography; D012016:Reference Values; D015203:Reproducibility of Results; D041623:Tomography, Optical Coherence; D014463:Ultrasonography; D055815:Young Adult