The recreational tryptamine 5-MeO-DALT (N,N-diallyl-5-methoxytryptamine): a brief review.
5-MeO-DALT (N,N-diallyl-5-methoxytryptamine) is a psychoactive substance, sold primarily over the Internet as a 'research chemical' or 'plant food'. Although details for the synthesis of this tryptamine have been available since 2004, its use as a hallucinogenic drug has been reported only occasionally in on-line user fora. It is controlled in only a few countries world-wide. There is little scientifically-based literature on the pharmacological, physiological, psychopharmacological, toxicological and epidemiological characteristics of 5-MeO-DALT. Here we review what is known about these aspects. We also report what we believe to be the first death involving the use of this substance. The case involved a man in his mid-20s who died in mid-2010. The coroner concluded that the deceased "died from injuries sustained after being hit by a lorry whilst under the influence of 5-MeODALT". It is critical that any other cases, including non-fatal instances, are documented so that a scientific evidence-base can be established for this drug.
National Programme for Substance Abuse Deaths (np-SAD), International Centre for Drug Policy, 6th floor Hunter Wing, St George's, University of London, Cranmer Terrace, London SW17 0RE, United Kingdom. jcorkery@sgul.ac.uk
John M
JM
Corkery
Emma
E
Durkin
Simon
S
Elliott
Fabrizio
F
Schifano
A Hamid
AH
Ghodse
D008735:5-Methoxytryptamine / Q000031:analogs & derivatives*; D000498:Allyl Compounds / Q000008:administration & dosage / Q000494:pharmacology / Q000633:toxicity; D000818:Animals; D004333:Drug Administration Routes; D004335:Drug and Narcotic Control / Q000639:trends; D006801:Humans; D013287:Illicit Drugs / Q000494:pharmacology / Q000600:supply & distribution / Q000633:toxicity*; D014363:Tryptamines / Q000008:administration & dosage / Q000494:pharmacology / Q000633:toxicity
D000498:Allyl Compounds; D013287:Illicit Drugs; D014363:Tryptamines; D008735:5-Methoxytryptamine; C578955:N,N-diallyl-5-methoxytryptamine