Erlotinib-related bilateral anterior uveitis.
The authors report the case of a 68-year-old woman with secondary adenocarcinoma of the lungs from an unknown primary. Erlotinib was started which produced symptoms suggestive of uveitis. Erlotinib was stopped and restarted a month later at a lower dose, which resulted in severe bilateral anterior uveitis. The uveitis settled after stopping erlotinib and treatment with topical steroids and cycloplegics. To the best of the authors' knowledge, this is the first case of erlotinib-related anterior uveitis.
Department of Ophthalmology, Countess of Chester Hospital, Chester, UK.
Kashif
K
Ali
Indu
I
Kumar
Muniba
M
Usman-Saeed
Muhammad
M
Usman Saeed
D000368:Aged; D000069347:Erlotinib Hydrochloride; D005260:Female; D006801:Humans; D047428:Protein Kinase Inhibitors / Q000009:adverse effects*; D011799:Quinazolines / Q000009:adverse effects*; D014606:Uveitis, Anterior / Q000139:chemically induced* / Q000175:diagnosis
D047428:Protein Kinase Inhibitors; D011799:Quinazolines; D000069347:Erlotinib Hydrochloride