Comparison of outcomes after typical and atypical eclampsia: a retrospective study.
OBJECTIVE
To evaluate the characteristics, clinical features and maternal-perinatal outcomes after atypical eclampsia.


METHODS
In a retrospective study, we compared demographics, clinical characteristics and outcomes between typical and atypical eclampsia.


RESULTS
Of 90 eclamptic patients, 56 had typical eclamptic features and 34 had atypical features. Compared to typical eclampsia, atypical eclampsia had higher gestational age (37.6 ± 3.3 vs. 34.6 ± 4.2 weeks, p = 0.001), a higher incidence of no antenatal risk factors [25 (73.5%) vs. 12 (21.4%), p < 0.001], less antepartum seizures [11 (32.4%) vs. 45 (80.4%), p < 0.001], a lower incidence of prodromal symptoms [20 (58.5%) vs. 49 (87.5%), p = 0.002], and a higher incidence of no lesion in brain imaging [16 (47.1%) vs. 12 (21.4%), p = 0.010). Although atypical eclampsia was associated with a lower odd ratio (OR) in composite perinatal complications (OR = 0.22, 95% CI = 0.08-0.60, p = 0.003), composite maternal complications did not differ between the two groups (OR = 0.52, 95% CI = 0.08-0.60, p =0.191).


CONCLUSIONS
Maternal outcomes did not differ between the two groups. Therefore, more attention should be focused on atypical eclampsia.
Department of Obstetrics and Gynecology, College of Medicine, Catholic University, Seoul, Korea.
Jae Eun
JE
Shin
Sun Young
SY
Nam
Young
Y
Lee
Guisera
G
Lee
Jong Chul
JC
Shin
Yeon Hee
YH
Kim
Ki Cheol
KC
Kil
D000328:Adult; D002585:Cesarean Section / Q000706:statistics & numerical data; D004461:Eclampsia / Q000145:classification / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D005260:Female; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D062706:Prodromal Symptoms; D012189:Retrospective Studies; D012307:Risk Factors; D012640:Seizures / Q000453:epidemiology; D055815:Young Adult