Gallium containing glass polyalkenoate anti-cancerous bone cements: glass characterization and physical properties.
A gallium (Ga) glass series (0.48SiO(2)-0.40ZnO-0.12CaO, with 0.08 mol% substitution for ZnO) was developed to formulate a Ga-containing Glass Polyalkenoate Cement (GPC) series. Network connectivity (NC) and X-ray Photoelectron Spectroscopy (XPS) was employed to investigate the role of Ga(3+) in the glass, where it is assumed to act as a network modifier. Ga-GPC series was formulated with E9 and E11 polyacrylic acid (PAA) at 50, 55 and 60 wt% additions. E11 working times (T(w)) ranged from 68 to 96 s (Lcon.) and 106 s for the Ga-GPCs (LGa-1 and LGa-2). Setting times (T(s)) ranged from 104 to 226 s (Lcon.) and 211 s for LGa-1 and LGa-2. Compression (σc) and biaxial flexural (σf) testing were conducted where Lcon. increased from 62 to 68 MPa, LGa-1 from 14 to 42 MPa and LGa-2 from 20 to 47 MPa in σc over 1-30 days. σf testing revealed that Lcon. increased from 29 to 42 MPa, LGa-1 from 7 to 32 MPa and LGa-2 from 12 to 36 MPa over 1-30 days.
Inamori School of Engineering, Alfred University, Alfred, NY 14802, USA. wren@alfred.edu
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D000268:Adhesiveness; D000970:Antineoplastic Agents / Q000737:chemistry*; D001843:Bone Cements / Q000737:chemistry*; D019245:Compressive Strength; D005708:Gallium / Q000737:chemistry*; D005899:Glass Ionomer Cements / Q000737:chemistry*; D006244:Hardness; D008422:Materials Testing; D014783:Viscosity
D000970:Antineoplastic Agents; D001843:Bone Cements; D005899:Glass Ionomer Cements; D005708:Gallium