[The positive response rate with QuantiFERON-TB GOLD In-Tube in patients with Mycobacterium avium complex].
OBJECTIVE
We studied the positive response rate with QuantiFERON-TB GOLD In-Tube in patients with Mycobacterium avium complex disease.


METHODS
We evaluated 62 subjects with M. avium complex disease. QuantiFERON-TB GOLD In-Tube was performed for all the subjects. The positive response rate with QuantiFERON-TB GOLD In-Tube and the history of pulmonary tuberculosis in patients who showed a positive response were evaluated.


RESULTS
Seven patients (11.3%) showed a positive response with QuantiFERON-TB GOLD In-Tube. These patients were elderly (age, 72-87 years) and had a history of pulmonary tuberculosis. Eleven other patients with a history of pulmonary tuberculosis showed a negative response with QuantiFERON-TB GOLD In-Tube.


CONCLUSIONS
Half or less than half of the elderly patients with M. avium complex disease and a history of pulmonary tuberculosis showed a positive response with QuantiFERON-TB GOLD In-Tube.
Department of General Internal Medicine 1, Kawasaki Hospital, Kawasaki Medical School, 2-1 -80, Nakasange, Kita-ku, Okayama-shi, Okayama 700-8505, Japan. n.okimoto@kawasaki-hp.jp
Niro
N
Okimoto
Fumiyo
F
Nanba
Takeyuki
T
Kurihara
Naoyuki
N
Miyashita
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D059425:Interferon-gamma Release Tests; D008297:Male; D008875:Middle Aged; D015270:Mycobacterium avium-intracellulare Infection / Q000175:diagnosis*; D014397:Tuberculosis, Pulmonary / Q000150:complications