Hepatitis B virus related membranous glomerulonephritis and proteinuria treated with lamivudine and tenofovir.
Membranous glomerulonephritis is the most common histological renal lesion associated with hepatitis B virus (HBV) infection. The authors describe here a case of a patient presenting with the nephrotic syndrome and HBV infection but without progressive liver disease. The use of lamivudine and tenofovir resulted in arrest of proteinuria and stabilisation of renal function.
Department of Nephrology and Transplantation, Guy and St Thomas Hospitals, NHS Foundation Trust, London, UK. parthadas@doctors.net.uk
Partha
P
Das
Vadamalai
V
Vivek
Martin
M
Ford
Edward
E
Kingdon
Stephen
S
Holt
D000225:Adenine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D015433:Glomerulonephritis, Membranous / Q000188:drug therapy* / Q000821:virology*; D019694:Hepatitis B, Chronic / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D019259:Lamivudine / Q000627:therapeutic use*; D008297:Male; D063065:Organophosphonates / Q000627:therapeutic use*; D011507:Proteinuria / Q000188:drug therapy* / Q000821:virology*; D018894:Reverse Transcriptase Inhibitors / Q000627:therapeutic use*; D000068698:Tenofovir; D055815:Young Adult
D063065:Organophosphonates; D018894:Reverse Transcriptase Inhibitors; D019259:Lamivudine; D000068698:Tenofovir; D000225:Adenine