Human papillomavirus type 16 DNA detected in pulmonary metastases from a penile squamous cell carcinoma: a case study.
This report describe the case of a patient presenting with pulmonary metastases from a penile cancer, where the presence of the human papillomavirus (HPV) type 16 DNA both in the primary tumor and in the distant metastases confirmed the spreading of the disease, ruling out a possible primary lung squamous cell carcinoma. Indeed, according to the findings, the HPV genotyping test might help in the identification of metastatic disease from anogenital malignancies or other HPV-related cancers.
University of Rome La Sapienza, Rome, Italy. laura.lorenzon@uniroma1.it
Laura
L
Lorenzon
Maria
M
Benevolo
Paolo
P
Visca
Irene
I
Venturo
Massimo
M
Filippetti
Francesca Romana
FR
Piro
Francesca
F
Rollo
Amina
A
Vocaturo
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000556:secondary / Q000821:virology*; D004279:DNA, Viral / Q000235:genetics / Q000302:isolation & purification*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D052162:Human papillomavirus 16 / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000821:virology*; D008297:Male; D030361:Papillomavirus Infections / Q000150:complications* / Q000473:pathology; D010412:Penile Neoplasms / Q000473:pathology / Q000821:virology*; D014057:Tomography, X-Ray Computed
D004279:DNA, Viral