Neuropsychological outcomes of U.S. Veterans with report of remote blast-related concussion and current psychopathology.
This study explored whether remote blast-related MTBI and/or current Axis I psychopathology contribute to neuropsychological outcomes among OEF/OIF veterans with varied combat histories. OEF/OIF veterans underwent structured interviews to evaluate history of blast-related MTBI and psychopathology and were assigned to MTBI (n = 18), Axis I (n = 24), Co-morbid MTBI/Axis I (n = 34), or post-deployment control (n = 28) groups. A main effect for Axis I diagnosis on overall neuropsychological performance was identified (F(3,100) = 4.81; p = .004), with large effect sizes noted for the Axis I only (d = .98) and Co-morbid MTBI/Axis I (d = .95) groups relative to the control group. The latter groups demonstrated primary limitations on measures of learning/memory and processing speed. The MTBI only group demonstrated performances that were not significantly different from the remaining three groups. These findings suggest that a remote history of blast-related MTBI does not contribute to objective cognitive impairment in the late stage of injury. Impairments, when present, are subtle and most likely attributable to PTSD and other psychological conditions. Implications for clinical neuropsychologists and future research are discussed. (JINS, 2012, 18, 1-11).
Graduate School of Professional Psychology, University of St. Thomas, Minneapolis, Minnesota 55403, USA. nels0600@stthomas.edu
Nathaniel W
NW
Nelson
James B
JB
Hoelzle
Bridget M
BM
Doane
Kathryn A
KA
McGuire
Amanda G
AG
Ferrier-Auerbach
Molly J
MJ
Charlesworth
Gregory J
GJ
Lamberty
Melissa A
MA
Polusny
Paul A
PA
Arbisi
Scott R
SR
Sponheim
D000328:Adult; D055826:Afghan Campaign 2001-; D000987:Antisocial Personality Disorder / Q000150:complications* / Q000209:etiology*; D001753:Blast Injuries / Q000150:complications*; D001924:Brain Concussion / Q000150:complications* / Q000209:etiology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D012189:Retrospective Studies; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis / Q000209:etiology; D015599:Trauma Severity Indices; D014481:United States / Q000453:epidemiology; D014728:Veterans / Q000523:psychology; D055815:Young Adult