Posterior reversible encephalopathy syndrome (PRES) complicating the 'legal high' mephedrone.
The authors report a 19-year-old woman who developed convulsions preceded by nasal ingestion of a cocaine mimic named 'the bubble' or mephedrone, obtained legally from a 'headshop' in Dublin. Characteristic posterior white matter oedema on brain imaging after the seizure suggested a diagnosis of posterior reversible encephalopathy syndrome (PRES). While PRES has been rarely associated with cocaine ingestion, this is the first report of an association with mephedrone.
Neurology Department, St James's Hospital, Dublin, Ireland. eldoory@hotmail.com
Taha Adam
TA
Omer
Colin
C
Doherty
D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D013287:Illicit Drugs / Q000506:poisoning*; D007494:Ireland; D008279:Magnetic Resonance Imaging; D008694:Methamphetamine / Q000031:analogs & derivatives* / Q000506:poisoning; D054038:Posterior Leukoencephalopathy Syndrome / Q000139:chemically induced* / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D055815:Young Adult
D013287:Illicit Drugs; D008694:Methamphetamine; C548233:mephedrone