Hallucinations after withdrawal of valproic acid.
We report 2 children with a history of epilepsy in whom valproic acid (VPA) withdrawal was identified as a potential cause of hallucinations. After a restart of VPA, the hallucinations disappeared. We suggest mechanisms for the occurrence of the hallucinations and a possible control of a predisposition to hallucinations by VPA.
Community Health Service, Hart voor Brabant, Netherlands.
Sanne A A
SA
de Laat
Manon H J
MH
Hillegers
Floor E
FE
Jansen
Kees P
KP
Braun
Elisabeth R
ER
de Graeff-Meeder
D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000188:drug therapy*; D005260:Female; D006212:Hallucinations / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis*; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
D000927:Anticonvulsants; D014635:Valproic Acid