A bilaterally recurring exophytic mass on the lower jaw.
Brown tumour is a rare focal giant-cell lesion that arises as a direct result of the effect of parathyroid hormone on bone tissue in patients with hyperparathyroidism (HPT). The lesions localise in areas of intense bone resorption, and the bone defect becomes filled with fibroblastic tissue. It can affect the mandible, maxilla, clavicle, ribs and pelvic bones. Therefore, diagnosis requires a systemic investigation for lesion differentiation. The authors present a case of a 27-year-old woman, with a rare case of brown tumour of mandible due to HPT secondary to osteomalacia. The lesion showed a tendency to recur even after excision till her parathyroid levels became normal.
Department of Oral and Maxillofacial Surgery, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
Shaji
S
Thomas
Preeti
P
Nair
Karthik
K
Hegde
Shiba
S
Neelakantan
D000328:Adult; D044963:Biopsy, Fine-Needle; D003937:Diagnosis, Differential; D005260:Female; D006101:Granuloma, Giant Cell / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications* / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D008336:Mandibular Diseases / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D010018:Osteomalacia / Q000150:complications*; D011862:Radiography, Panoramic; D018084:Ultrasonography, Interventional