Prevention of novel influenza infection in newborns in hospital settings: considerations and strategies during the 2009 H1N1 pandemic.
During the 2009 influenza A (H1N1) pandemic, many pregnant women experienced severe illness and some gave birth while ill with suspected or confirmed pandemic (H1N1) 2009 influenza. Because of concerns about possible transmission of this novel virus to immunologically naïve newborns, and the absence of definitive studies regarding this risk, the Centers for Disease Control and Prevention (CDC) reviewed relevant literature to understand the potential burden of disease and routes of transmission affecting newborns. This report describes the issues considered during the 2009 H1N1 pandemic as CDC developed guidance to protect newborns in hospital settings. Also presented is a framework of protection efforts to prevent novel influenza infection in fetuses/newborns before birth and in hospital settings. Although developed specifically for the pandemic, the framework may be useful during future novel influenza outbreaks.
Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. lzapata@cdc.gov
Lauren B
LB
Zapata
Juliette S
JS
Kendrick
Denise J
DJ
Jamieson
Kitty
K
MacFarlane
Katherine
K
Shealy
Wanda D
WD
Barfield
D000998:Antiviral Agents / Q000008:administration & dosage; D003428:Cross Infection / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D006282:Health Personnel; D006739:Hospital Administration; D006801:Humans; D007231:Infant, Newborn; D017053:Infection Control / Q000458:organization & administration*; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D053118:Influenza A Virus, H1N1 Subtype; D007252:Influenza Vaccines / Q000008:administration & dosage; D007251:Influenza, Human / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission; D008895:Milk, Human; D058873:Pandemics / Q000517:prevention & control; D014481:United States
D000998:Antiviral Agents; D007252:Influenza Vaccines