Dynamic magnetic resonance angiography for localization of hyperfunctioning parathyroid glands in the reoperative neck.
OBJECTIVE
To evaluate the use of dynamic magnetic resonance angiography for localization of hyperfunctioning parathyroid glands in the reoperative neck.


METHODS
We retrospectively evaluated the head-neck MRIs of 30 patients with a history of hyperparathyroidism, prior head-neck surgery, and intraoperative proven adenomas. The protocol included conventional imaging with T2-weighted STIR sequences, T1w axial and coronal prior to and after contrast media administration, and dynamic magnetic resonance angiography. We compared the results from MRI, dynamic magnetic resonance angiography with 99m-Tc-Sestamibi with intraoperative findings as the gold standard.


RESULTS
In conventional MRI 19/30 true positives were detected with a sensitivity and specificity of 63.3% and 100%, respectively. However, by adding dynamic magnetic resonance angiography the detection rate increased to 28/30 true positives. Based on intraoperative findings, the sensitivity and specificity of dynamic magnetic resonance angiography were 93.3% and 100%, respectively. 99m-Tc-Sestamibi detected 24/30 true positives, sensitivity was 80%.


CONCLUSIONS
The diagnostic value of MRI including dynamic magnetic resonance angiography is superior to MRI alone and superior to that of 99m-Tc-Sestamibi in the diagnostic workup of hyperfunctioning parathyroid glands when compared against intraoperative findings.
HELIOS Hospital Erfurt, Department of Diagnostic and Interventional Radiology and Neuroradiology, Nordhaeuser Str. 74, 99089 Erfurt, Germany. rene.aschenbach@helios-kliniken.de
R
R
Aschenbach
S
S
Tuda
E
E
Lamster
A
A
Meyer
H
H
Roediger
A
A
Stier
E
E
Conrad
S
S
Basche
J
J
Klisch
T J
TJ
Vogl
D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000473:pathology* / Q000601:surgery*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity