Immunotherapy in clinical medicine: historical perspective and current status.
In humans, the immune system is a complex organ system involving cells and soluble mediators whose function is, essentially, protection. However, disequilibrium in this intricate system leads to disease in itself. To modulate these responses, immunotherapy is now the primary or adjunct treatment of many diseases. In addition, immunologic tests now diagnose several diseases.
Department of Medicine, Southern Illinois University School of Medicine, 801 North Rutledge, PO Box 9636, Springfield, IL 62794, USA.
Lokesh
L
Shahani
Sushma
S
Singh
Nancy Misri
NM
Khardori
D000485:Allergens / Q000276:immunology; D000911:Antibodies, Monoclonal / Q000266:history / Q000627:therapeutic use; D019496:Cancer Vaccines; D003888:Desensitization, Immunologic / Q000639:trends*; D005818:Genetic Engineering; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology / Q000628:therapy; D007154:Immune System Diseases / Q000175:diagnosis; D007116:Immunization, Passive / Q000639:trends*; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007159:Immunologic Tests; D009369:Neoplasms / Q000276:immunology / Q000628:therapy; D014611:Vaccination / Q000639:trends*
D000485:Allergens; D000911:Antibodies, Monoclonal; D019496:Cancer Vaccines; D016756:Immunoglobulins, Intravenous