ST-segment elevation during levosimendan infusion.
Levosimendan increases the sensitivity of the heart to calcium and consequently exerts positive inotropic effects. Levosimendan is indicated in acutely decompensated severe congestive heart failure. We report that levosimendan infusion may induce myocardial ischemia in patients with acute heart failure.
Department of Heart and Great Vessels 'Attilio Reale', La Sapienza University of Rome. francesco.barilla@uniroma1.it
Francesco
F
Barillà
Federica
F
Giordano
Ilaria
I
Jacomelli
Mariano
M
Pellicano
Tania
T
Dominici
D054058:Acute Coronary Syndrome / Q000139:chemically induced* / Q000000981:diagnostic imaging; D002316:Cardiotonic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D017023:Coronary Angiography; D004562:Electrocardiography / Q000187:drug effects*; D005260:Female; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D006835:Hydrazones / Q000008:administration & dosage / Q000009:adverse effects*; D007262:Infusions, Intravenous; D008875:Middle Aged; D011724:Pyridazines / Q000008:administration & dosage / Q000009:adverse effects*; D000077464:Simendan
D002316:Cardiotonic Agents; D006835:Hydrazones; D011724:Pyridazines; D000077464:Simendan