An unexpected silver triflate-catalyzed tandem reaction of N'-(2-alkynylbenzylidene)hydrazide with ketene.
An unexpected silver triflate-catalyzed tandem reaction of N'-(2-alkynylbenzylidene)hydrazide with ketene through 6-endo-cyclization, [3+2] cycloaddition and rearrangement is reported. This reaction proceeds efficiently to generate the molecular complexity with the formation of four bonds in a one-pot procedure.
Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.
Gang
G
Liu
Hongliang
H
Liu
Guanyinsheng
G
Qiu
Shouzhi
S
Pu
Jie
J
Wu
D000480:Alkynes / Q000737:chemistry*; D053961:Azabicyclo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D001597:Benzylidene Compounds / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D005030:Ethylenes / Q000737:chemistry*; D006834:Hydrazines / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure
D000480:Alkynes; D053961:Azabicyclo Compounds; D001597:Benzylidene Compounds; D005030:Ethylenes; D006834:Hydrazines; D007659:Ketones; D008698:Mesylates; C012077:trifluoromethanesulfonic acid; C008223:ketene