Ru(II)-catalyzed C-H bond activation for the synthesis of substituted isoquinolinium salts from benzaldehydes, amines, and alkynes.
An efficient method for the synthesis of substituted isoquinolinium salts from benzaldehydes, amines, and alkynes via ruthenium-catalyzed C-H bond activation and annulation in one pot is described.
Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan.
Kanniyappan
K
Parthasarathy
Natarajan
N
Senthilkumar
Jayachandran
J
Jayakumar
Chien-Hong
CH
Cheng
D000480:Alkynes / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D001547:Benzaldehydes / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*; D012492:Salts / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism
D000480:Alkynes; D000588:Amines; D001547:Benzaldehydes; D007546:Isoquinolines; D009942:Organometallic Compounds; D012492:Salts; D012428:Ruthenium