Effects of flecainide therapy on inappropriate shocks and arrhythmias in catecholaminergic polymorphic ventricular tachycardia.
We report the case of a child with catecholaminergic polymorphic ventricular tachycardia, who had inappropriate electric shocks by an implantable cardioverter defibrillator and from recurrence of arrhythmias despite an appropriate β-blocking treatment. An additional treatment by flecainide completely suppressed inappropriate shocks due to sinusal tachycardia and ventricular tachyarrhythmias. We briefly discuss the potentially interesting effect of flecainide in this specific arrhythmia.
Division of Pediatric Cardiology, Queen Fabiola Children's University Hospital, HUDERF, Free University of Brussels, ULB, Brussels, Belgium.
Caroline
C
Jacquemart
Fazia
F
Ould Abderrahmane
Martial M
MM
Massin
D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D002675:Child, Preschool; D017147:Defibrillators, Implantable / Q000009:adverse effects*; D004868:Equipment Failure; D005424:Flecainide / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010138:Pacemaker, Artificial; D055502:Secondary Prevention; D017180:Tachycardia, Ventricular / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control*; D016896:Treatment Outcome; D000098850:Polymorphic Catecholaminergic Ventricular Tachycardia
D000889:Anti-Arrhythmia Agents; D005424:Flecainide