Primary angiosarcoma of the bladder in a young female.
Our case report pertains to a 32-year-old woman initially presenting with left flank pain and gross haematuria throughout her urinary stream. CT of her kidney/ureter/bladder (CT KUB) revealed ureteric dilatation to the level of the bladder without evidence of renal calculus and subsequently a stent was inserted. She represented a month later with contralateral flank pain, and a transuretheral resection of bladder tumour was performed. Histopathological diagnosis was epithelioid angiosarcoma. Further imaging (MRI pelvis) revealed that the tumour arose from the posterior bladder wall with local invasion and regional lymph node metastasis. Ifosfamide and epirubicin chemotherapy with single-fraction radiotherapy induced significant reduction in tumour bulk, although this initial response was followed by the development of symptoms suggestive of disease progression. She died 19 months after initial diagnosis with persistent pulmonary and vertebral metastases although no autopsy was performed.
Department of Radiology, Royal Perth Hospital, Perth, Western Australia, Australia. Richard.Warne@health.wa.gov.au
Richard R
RR
Warne
Jeremy S L
JS
Ong
Bret
B
Snowball
Justin B
JB
Vivian
D000328:Adult; D005260:Female; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000601:surgery