A dramatic concentration effect on the stereoselectivity of N-glycosylation for the synthesis of 2'-deoxy-β-ribonucleosides.
A dramatic concentration effect on the stereoselectivity of N-glycosylation, which is attributable to a low-concentration-facilitated remote-participation, has been disclosed, leading to convenient synthesis of the 2'-deoxy-β-ribonucleosides of biological significance.
State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
Fei
F
Yang
Yugen
Y
Zhu
Biao
B
Yu
D006031:Glycosylation; D008968:Molecular Conformation; D011684:Purine Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D011684:Purine Nucleosides