Analysis of population structure among Korean and Japanese Legionella pneumophila isolates using hsp60 sequences.
The population structure of Korean (150 strains) and Japanese (92 strains) Legionella pneumophila isolates along with 18 reference strains were investigated using hsp60 sequence (1647 bp) analysis. Twelve clonal subgroups (hsP-I to hsP-X and hsF-I and hsF-II) were designated on the hsp60 tree, inferred from representative sequences using the neighbor-joining method. Some of the isolates showed unique subgroups depending on the source of isolates, including hsP-I, hsF-I, and hsF-II from cooling tower water, and subgroups hsP-VIII and hsP-X from circulating hot water bath. These subgroups may be useful for epidemiological studies to chase or specify sources of infection in Korea and Japan.
Department of Microbiology and Institute of Endemic Diseases, Seoul National University College of Medicine (SNUMRC), Seoul National University Hospital, Seoul, Korea.
Chan Geun
CG
Park
Byoung Jun
BJ
Kim
Hee-Youn
HY
Kim
Yeo-Jun
YJ
Yun
Kwan Soo
KS
Ko
Hiroshi
H
Miyamoto
Bum-Joon
BJ
Kim
Yoon-Hoh
YH
Kook
D001426:Bacterial Proteins / Q000235:genetics; D018834:Chaperonin 60 / Q000235:genetics*; D016000:Cluster Analysis; D004783:Environmental Microbiology; D014644:Genetic Variation; D006801:Humans; D007564:Japan / Q000453:epidemiology; D007723:Korea / Q000453:epidemiology; D016952:Legionella pneumophila / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000453:epidemiology / Q000382:microbiology*; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D017385:Sequence Homology
D001426:Bacterial Proteins; D018834:Chaperonin 60