Lipids at the interface of virus-host interactions.
Viruses physically and metabolically remodel the host cell to establish an optimal environment for their replication. Many of these processes involve the manipulation of lipid signaling, synthesis, and metabolism. An emerging theme is that these lipid-modifying pathways are also linked to innate antiviral responses and can be modulated to inhibit viral replication.
Department of Microbiology, The University of Chicago, Chicago, IL 60637, United States.
Vineela
V
Chukkapalli
Nicholas S
NS
Heaton
Glenn
G
Randall
D055372:AMP-Activated Protein Kinases; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism* / Q000821:virology; D004266:DNA Virus Infections / Q000276:immunology / Q000821:virology; D004267:DNA Viruses / Q000276:immunology / Q000472:pathogenicity / Q000502:physiology*; D054884:Host-Pathogen Interactions; D006801:Humans; D007113:Immunity, Innate; D050356:Lipid Metabolism; D012327:RNA Virus Infections / Q000276:immunology / Q000821:virology; D012328:RNA Viruses / Q000276:immunology / Q000472:pathogenicity / Q000502:physiology*; D015398:Signal Transduction; D014779:Virus Replication
D055372:AMP-Activated Protein Kinases