Genomic analysis of ICEVchBan8: An atypical genetic element in Vibrio cholerae.
Genomic islands (GIs) and integrative conjugative elements (ICEs) are major players in bacterial evolution since they encode genes involved in adaptive functions of medical or environmental importance. Here we performed the genomic analysis of ICEVchBan8, an unusual ICE found in the genome of a clinical non-toxigenic Vibrio cholerae O37 isolate. ICEVchBan8 shares most of its genetic structure with SXT/R391 ICEs. However, this ICE codes for a different integration/excision module is located at a different insertion site, and part of its genetic cargo shows homology to other pathogenicity islands of V. cholerae.
Maryland Pathogen Research Institute, University of Maryland, College Park, MD 20742, USA.
Elisa
E
Taviani
Matteo
M
Spagnoletti
Daniela
D
Ceccarelli
Bradd J
BJ
Haley
Nur A
NA
Hasan
Arlene
A
Chen
Mauro M
MM
Colombo
Anwar
A
Huq
Rita R
RR
Colwell
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D002771:Cholera / Q000453:epidemiology / Q000382:microbiology; D005798:Genes, Bacterial / Q000235:genetics*; D044404:Genomic Islands / Q000235:genetics; D023281:Genomics; D006801:Humans; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000235:genetics; D058873:Pandemics; D014734:Vibrio cholerae / Q000235:genetics* / Q000378:metabolism / Q000472:pathogenicity
D001426:Bacterial Proteins