Optic disc and retinal nerve fiber layer parameters of eyes with keratoconus.
OBJECTIVE
To evaluate optic nerve head (ONH) characteristics and retinal nerve fiber layer (RNFL) thickness measurements in patients with nonglaucomatous keratoconus.


METHODS
This was a cross-sectional, observational study in which 46 patients with keratoconus and 74 healthy subjects were included. Analysis of ONH and RNFL imaging were performed by confocal scanning laser ophthalmoscopy and optical coherence tomography, respectively.


RESULTS
Eyes with keratoconus had larger disc area (2.37 ± 0.5 vs 2.17 ± 0.36 mm(2)) (P = .013), larger cup area (0.65 ± 0.53 vs 0.49 ± 0.28 mm(2)) (P = .035) and deeper cup depths (for mean cup depth 0.24 ± 0.09 vs 0.20 ± 0.07 mm, P = .008 and for maximum cup depth 0.69 ± 0.27 vs 0.60 ± 0.17 mm, P = .037) than control group eyes. Height variation contour also differed in the two groups (P = .007) but RNFL measurements did not.


CONCLUSIONS
RNFL thickness between patients with keratoconus and healthy subjects seems to be more comparable than ONH parameters.
2nd Eye Clinic, Ankara Ulucanlar Eye Research Hospital, Ankara, Turkey. abcankaya@hotmail.com
Ali Bulent
AB
Cankaya
Emrullah
E
Beyazyildiz
Dilek
D
Ileri
Pelin
P
Yilmazbas
D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007640:Keratoconus / Q000150:complications*; D008297:Male; D018613:Microscopy, Confocal; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D009887:Ophthalmoscopy; D009898:Optic Disk / Q000473:pathology*; D011446:Prospective Studies; D012165:Retinal Ganglion Cells / Q000473:pathology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity; D055815:Young Adult