Reversible steatohepatosis in a young boy with brittle type 1 diabetes mellitus: mauriac syndrome.
A 14-year-old male, diagnosed case of type 1 diabetes mellitus since 1 year, presented with uncontrolled blood glucose levels, non-compliance with insulin therapy and recurrent admissions with diabetic ketoacidosis. His blood glucose levels were difficult to control with wide fluctuations in insulin requirement. He had absent secondary sexual characteristics and hepatomegaly. Liver biopsy showed macrovesicularsteatosis without fibrosis or inflammation. Many glycogenated nuclei were present. He was started on intensive insulin therapy, whereby he showed subsequent regression of hepatomegaly and onset of pubertal spurt.
Department of Internal Medicine, Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai, India. makar_in@rediffmail.com
Makardhwaj Sarvadaman
MS
Shrivastava
Atul Vijay
AV
Palkar
Namita J
NJ
Padwal
Nivedita
N
Moulick
D000293:Adolescent; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000188:drug therapy; D004392:Dwarfism / Q000188:drug therapy / Q000209:etiology*; D005234:Fatty Liver / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D012074:Remission Induction; D013577:Syndrome