miR-23a, a critical regulator of "migR"ation and metastasis in colorectal cancer.
Jahid and colleagues have shown that miR-23a promotes the transition from indolent to invasive colorectal cancer through inhibition of the MTSS1 tumor suppressor. This study reveals a novel role of miR-23a in the acceleration of colorectal cancer progression.
Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Zhiwei
Z
Wang
Wenyi
W
Wei
Fazlul H
FH
Sarkar
D000230:Adenocarcinoma / Q000235:genetics*; D000236:Adenoma / Q000235:genetics*; D000818:Animals; D015179:Colorectal Neoplasms / Q000235:genetics*; D006801:Humans; D035683:MicroRNAs / Q000235:genetics*
D035683:MicroRNAs; C534062:Mirn23b microRNA, mouse