Exploratory planning and implementation of a pilot pharmacogenetic program in a community pharmacy.
OBJECTIVE
To describe the exploratory planning and implementation of a pilot pharmacogenetic program in a community pharmacy. An institutional review board-approved protocol for a clopidogrel pharmacogenetic program in a community pharmacy was developed to address feasibility and evaluate the pilot program.
Subjects taking clopidogrel are asked to participate at the point of medication dispensing. A pharmacist schedules an appointment with subjects to discuss the study and collects a buccal swab sample for CYP2C19 testing. When the results are available, the pharmacist consults with the subject's prescriber regarding test result interpretation and associated recommendations, and schedules a second appointment with the participant to discuss results and review any physician-approved therapeutic changes. The intervention-associated consultation is then billed to the subject's insurance.


RESULTS
Subject enrollment has begun.


CONCLUSIONS
Community pharmacists may be valuable partners in pharmacogenetics.
Division of Pharmacy Practice & Experiential Education CB #7574, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7574, USA.
Shanna K
SK
O'Connor
Stefanie P
SP
Ferreri
Natasha M
NM
Michaels
Angelo J
AJ
Greco
Anthony J
AJ
Viera
Hawazin
H
Faruki
Howard L
HL
McLeod
Mary W
MW
Roederer
D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics*; D065731:Cytochrome P-450 CYP2C19; D011307:Drug Prescriptions; D005820:Genetic Testing; D006801:Humans; D010594:Pharmacies; D010595:Pharmacists; D010597:Pharmacogenetics / Q000379:methods*
D001189:Aryl Hydrocarbon Hydroxylases; C045793:CYP2C19 protein, human; D065731:Cytochrome P-450 CYP2C19