How to regulate a gene: to repress or to activate?
Gene-expression responses to an input can depend on growth conditions; in this issue, Sasson et al. (2012) show that this dependence is lower when the input results in a high degree of promoter occupancy.
Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Nikolai
N
Slavov
Alexander
A
van Oudenaarden