Induced pluripotent stem cells: past, present, and future.
The development of iPSCs reflected the merging of three major scientific streams and has in turn led to additional new branches of investigation. However, there is still debate about whether iPSCs are functionally equivalent to ESCs. This question should be answered only by science, not by politics or business.
Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan; Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. Electronic address: yamanaka@cira.kyoto-u.ac.jp.
Shinya
S
Yamanaka
D000818:Animals; D002454:Cell Differentiation; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology* / Q000502:physiology* / Q000637:transplantation