Dietary whey protein lessens several risk factors for metabolic diseases: a review.
Obesity and type 2 diabetes mellitus (DM) have grown in prevalence around the world, and recently, related diseases have been considered epidemic. Given the high cost of treatment of obesity/DM-associated diseases, strategies such as dietary manipulation have been widely studied; among them, the whey protein diet has reached popularity because it has been suggested as a strategy for the prevention and treatment of obesity and DM in both humans and animals. Among its main actions, the following activities stand out: reduction of serum glucose in healthy individuals, impaired glucose tolerance in DM and obese patients; reduction in body weight; maintenance of muscle mass; increases in the release of anorectic hormones such as cholecystokinin, leptin, and glucagon like-peptide 1 (GLP-1); and a decrease in the orexigenic hormone ghrelin. Furthermore, studies have shown that whey protein can also lead to reductions in blood pressure, inflammation, and oxidative stress.
Departamento de Fisiologia e Biofísica, Instituto de Ciências Biomédicas, Universidade de São Paulo-USP, São Paulo/SP, Brazil.
Gabriela T D
GT
Sousa
Fábio S
FS
Lira
José C
JC
Rosa
Erick P
EP
de Oliveira
Lila M
LM
Oyama
Ronaldo V
RV
Santos
Gustavo D
GD
Pimentel
D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000517:prevention & control; D004044:Dietary Proteins / Q000627:therapeutic use*; D006801:Humans; D008894:Milk Proteins / Q000627:therapeutic use*; D009765:Obesity / Q000517:prevention & control; D012307:Risk Factors; D000067816:Whey Proteins
D004044:Dietary Proteins; D008894:Milk Proteins; D000067816:Whey Proteins