Outer-sphere direction in iridium C-H borylation.
The NHBoc group affords ortho selective C-H borylations in arenes and alkenes. Experimental and computational studies support an outer sphere mechanism where the N-H proton hydrogen bonds to a boryl ligand oxygen. The regioselectivities are unique and complement those of directed ortho metalations.
Department of Chemistry, Michigan State University, East Lansing, Michigan 48824-1322, USA.
Philipp C
PC
Roosen
Venkata A
VA
Kallepalli
Buddhadeb
B
Chattopadhyay
Daniel A
DA
Singleton
Robert E
RE
Maleczka
Milton R
MR
Smith
D001896:Boron Compounds / Q000737:chemistry*; D002384:Catalysis; D006860:Hydrogen Bonding; D007495:Iridium / Q000737:chemistry*; D008958:Models, Molecular
D001896:Boron Compounds; D007495:Iridium