Chromoblastomycosis.
Chromoblastomycosis is a chronic, subcutaneous mycosis, characterized by verrucous nodular lesions, usually involving the legs and mainly caused by Fonsecaea, Phialophora, and Cladophialophora spp. The characteristic finding on direct examination or biopsy specimen is the presence of fumagoid cells or Medlar bodies. Chromoblastomycosis can be refractory to medical treatment. Therapeutic options include oral itraconazole, terbinafine, or 5-fluocytosine, alone or combined with surgery or cryosurgery.
Mycology Section, Department of Dermatology, Dr. Manuel Gea Gonzalez General Hospital, Calzada de Tlalpan 4800, Colonia Sección XVI, Mexico, DF Mexico.
Edoardo
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Torres-Guerrero
Rafael
R
Isa-Isa
Mariel
M
Isa
Roberto
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Arenas
D000293:Adolescent; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D001203:Ascomycota / Q000302:isolation & purification*; D002862:Chromoblastomycosis / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D003452:Cryosurgery / Q000379:methods*; D004359:Drug Therapy, Combination; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D003904:Mitosporic Fungi / Q000302:isolation & purification*; D009281:Naphthalenes / Q000627:therapeutic use; D000077291:Terbinafine; D055815:Young Adult
D000935:Antifungal Agents; D009281:Naphthalenes; D017964:Itraconazole; D015725:Fluconazole; D000077291:Terbinafine