Advanced and rapidly progressing head and neck cancer: good palliation following intralesional bleomycin.
The authors herein report the case of a 61-year-old man undergoing adjuvant therapy for locally advanced laryngeal cancer, who developed parastomal recurrence in his radiation field around his tracheotomy site, while he was undergoing radiation therapy, and compromised the secure placement of his tracheotomy tube and maintenance of his upper airway. MRI restaging and biopsy confirmed recurrence and progressive disease in his mediastinum. He underwent local therapy with intralesional bleomycin with good palliation, and ability to maintain the patency of his upper airway.
Department of Medical Oncology, Mid-Western Regional Hospital, Limerick, Ireland. keithi.quintyne@hse.ie
Keith Ian
KI
Quintyne
Shirley
S
Baker
Fintan
F
Wallis
Neville
N
Shine
Rajnish
R
Gupta
D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use*; D001761:Bleomycin / Q000627:therapeutic use*; D018450:Disease Progression; D006258:Head and Neck Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy; D006801:Humans; D015552:Injections, Intralesional; D007825:Laryngectomy; D008197:Lymph Node Excision; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D014139:Tracheostomy
D000903:Antibiotics, Antineoplastic; D001761:Bleomycin