Fetal-maternal interface: a chronicle of allogeneic coexistence.
The existence of allogeneic cells within an individual has been demonstrated in multiple fields such as hematopoietic stem cell or solid organ transplantation, non-depleted blood transfusions and the most common form which is bidirectional maternal-fetal cell trafficking, whereby cells from the fetus pass through the placental barrier. In order to graphically illustrate this early natural phenomenon that initiates the journey of a child's cells within the mother's blood and other tissues, we used a new procedure in microscopy imaging generating Large Scale Panoramic Pictures (LSPP). This technique can also be extended to explore a broad diversity of experimental models.
ICREC Research Group, Health Sciences Research Institute Germans Trias i Pujol, Barcelona, Spain.
Josep-Maria
JM
Pujal
Santiago
S
Roura
Ana M
AM
Muñoz-Marmol
Jose-Luis
JL
Mate
Antoni
A
Bayes-Genis
D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008431:Maternal-Fetal Exchange / Q000235:genetics / Q000502:physiology; D011247:Pregnancy; D014184:Transplantation, Homologous