2-Hydroxyglutarate in IDH mutant acute myeloid leukemia: predicting patient responses, minimal residual disease and correlations with methylcytosine and hydroxymethylcytosine levels.
Daniel A
DA
Pollyea
Holbrook E
HE
Kohrt
Bing
B
Zhang
James
J
Zehnder
David
D
Schenkein
Valeria
V
Fantin
Kimberly
K
Straley
Aparna
A
Vasanthakumar
Omar
O
Abdel-Wahab
Ross
R
Levine
Lucy A
LA
Godley
Bruno C
BC
Medeiros
D044503:5-Methylcytosine / Q000031:analogs & derivatives / Q000097:blood; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005977:Glutarates / Q000097:blood*; D006801:Humans; D007521:Isocitrate Dehydrogenase / Q000235:genetics*; D015470:Leukemia, Myeloid, Acute / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics*; D008297:Male; D009154:Mutation; D018365:Neoplasm, Residual; D011379:Prognosis; D012074:Remission Induction; D016896:Treatment Outcome
D005977:Glutarates; C019417:alpha-hydroxyglutarate; D044503:5-Methylcytosine; D007521:Isocitrate Dehydrogenase