Universal HIV testing in London tuberculosis clinics: a cluster randomised controlled trial.
We assessed whether implementation of a combination of interventions in London tuberculosis clinics raised the levels of HIV test offers, acceptance and coverage. A stepped-wedge cluster randomised controlled trial was conducted across 24 clinics. Interventions were training of clinical staff and provision of tailor-made information resources with or without a change in clinic policy from selective to universal HIV testing. The primary outcome was HIV test acceptance amongst those offered a test, before and after the intervention; the secondary outcome was an offer of HIV testing. Additionally, the number and proportion of HIV tests among all clinic attendees (coverage) was assessed. 1,315 patients were seen in 24 clinics. The offer and coverage of testing rose significantly in clinics without (p = 0.002 and p = 0.004, respectively) and with an existing policy of universal testing (p = 0.02 and p = 0.04, respectively). However, the level of HIV test acceptance did not increase in 18 clinics without routine universal testing (p = 0.76) or the six clinics with existing universal testing (p = 0.40). The intervention significantly increased the number of HIV tests offered and proportion of participants tested, although acceptance did not change significantly. However, the magnitude of increase is modest due to the high baseline coverage.
Health Protection Agency, UK.
Anjana
A
Roy
Sudy
S
Anaraki
Pia
P
Hardelid
Mike
M
Catchpole
Laura C
LC
Rodrigues
Marc
M
Lipman
Samantha
S
Perkins
Anita
A
Roche
Helen R
HR
Stagg
Jose
J
Figueroa
Ibrahim
I
Abubakar
D000293:Adolescent; D000328:Adult; D000368:Aged; D000554:Ambulatory Care Facilities; D003140:Communicable Disease Control / Q000379:methods*; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008131:London; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D015233:Models, Statistical; D010342:Patient Acceptance of Health Care; D016896:Treatment Outcome; D014376:Tuberculosis / Q000150:complications* / Q000628:therapy*; D055815:Young Adult