Beyond the blot: cutting edge tools for genomics, proteomics and metabolomics analyses and previous successes.
The skin has an amazing array of complex interacting biological processes. Recent advances in investigational techniques now allow evaluation of these processes at the level of the gene, protein and metabolite. Sometimes collectively known as the omics, these fields of inquiry, known as genomics, proteomics and metabolomics, respectively, are yielding new and important insights into skin structure and processes, its responses to injury and age, and the mechanisms by which new interventions and compounds may work to improve the health and integrity of this crucial organ.
Harvard Medical School, Boston, MA, USA.
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Kimball
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Grant
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Wang
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Osborne
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Tiesman
D002845:Chromatography / Q000379:methods; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005544:Forecasting; D015870:Gene Expression / Q000235:genetics; D023281:Genomics / Q000379:methods / Q000639:trends*; D006801:Humans; D055432:Metabolomics / Q000379:methods / Q000639:trends*; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods; D040901:Proteomics / Q000379:methods / Q000639:trends; D012879:Skin Physiological Phenomena / Q000235:genetics*; D013057:Spectrum Analysis / Q000379:methods