Severe tremor due to vancomycin therapy: a case report and literature review.
Vancomycin is a popular antimicrobial used to treat a variety of Gram-positive infections. Its side effect profile has been well defined due to its high global utilization as a result of the emergence of antimicrobial-resistant organisms in recent decades. Despite its widespread use, however, various idiosyncratic reactions may occur without adequate or universal reporting. We present a case of severe tremor due to vancomycin that has not been previously reported in the literature. Our patient might have been prone to this adverse effect given an underlying essential tremor. Causality is presumed based on the temporal association, while the pathophysiological link remains elusive.
Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Luc
L
Benoit
Margaret H
MH
Gray
Wendy I
WI
Sligl
D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D004696:Endocarditis / Q000188:drug therapy; D005260:Female; D006801:Humans; D014202:Tremor / Q000139:chemically induced*; D014640:Vancomycin / Q000009:adverse effects* / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D014640:Vancomycin