Makomotindoline from Makomotake, Zizania latifolia infected with Ustilago esculenta.
Makomotindoline (1) was isolated from Makomotake, Zizania latifolia infected with Ustilago esculenta. The structure was determined by the interpretation of spectroscopic data and synthesis. Makomotindoline (1), its l-Glc isomer (2) and its aglycon (3) were synthesized and their effects on rat glioma cells showed adverse effects on the cell growth.
Graduate School of Science and Technology, Shizuoka University, 836 Ohya, Suruga-ku, Shizuoka 422-8529, Japan.
Tomohiro
T
Suzuki
Jae-Hoon
JH
Choi
Takumi
T
Kawaguchi
Kimiko
K
Yamashita
Akio
A
Morita
Hirofumi
H
Hirai
Kaoru
K
Nagai
Tomoyasu
T
Hirose
Satoshi
S
Omura
Toshiaki
T
Sunazuka
Hirokazu
H
Kawagishi
D000818:Animals; D049109:Cell Proliferation / Q000187:drug effects; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D007211:Indoles / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D006109:Poaceae / Q000737:chemistry* / Q000382:microbiology; D051381:Rats; D013237:Stereoisomerism; D014588:Ustilago / Q000502:physiology*
D006027:Glycosides; D007211:Indoles