Drug induced neutropaenia--a trigger for necrotising fasciitis?
The authors present a case of necrotising fasciitis of the peristomal area, in a patient who had undergone a previous ileostomy for ulcerative colitis. This was associated with neutropaenia, secondary to carbimazole, which had been commenced a few weeks previously for thyrotoxicosis. The authors therefore, stress the importance of monitoring patients closely for possible side effects and complications, while they are on immunosuppressive medication.
General Surgery Department, Nevill Hall Hospital, Abergavenny, UK. FoulkesRE@doctors.org.uk
Rhiannon
R
Foulkes
David
D
Hoare
Krishnamurthy
K
Somasekar
D000328:Adult; D013956:Antithyroid Agents / Q000009:adverse effects*; D002231:Carbimazole / Q000009:adverse effects*; D019115:Fasciitis, Necrotizing / Q000209:etiology*; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000139:chemically induced* / Q000150:complications*
D013956:Antithyroid Agents; D002231:Carbimazole