The first documented case of Candida dubliniensis leptomeningeal disease in an immunocompetent host.
In June 2008, a 25-year-old man presented to the Royal Adelaide Hospital, Australia, with Candida dubliniensis leptomeningeal disease. On examination the patient had focal neurological deficits, both sensory and motor. He tested negative for HIV and had normal T cell subsets. The patient was treated with 6 weeks of intravenous liposomal amphotericin B and oral flucytosine, and had a full recovery.
Department of Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia. nick.h.andrew@gmail.com
Nicholas H
NH
Andrew
Ravi P
RP
Ruberu
Genevieve
G
Gabb
D000328:Adult; D002177:Candidiasis / Q000175:diagnosis*; D020314:Central Nervous System Fungal Infections / Q000175:diagnosis*; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008578:Meninges