[Neuroprotective treatment with citicoline (ceraxon) in patients with ischemic stroke].
The dynamics of neurological symptoms assessed with the Scandinavian stroke scale, the Barthel index and the modified Rankin scale was studied in 89 patients with moderate ischemic stroke who received citicoline (ceraxone) intravenously and orally. The results were compared to a group of 52 age-, sex- and stroke-matched patients who did not receive citicoline. To the date of discharge from the hospital (days 21-24), the full restoration (p<0.05) was noted in patients of the main group. Efficacy of citicoline was significantly (p<0.05) higher in patients younger than 70 years and when the drug was used in the first hours of disease.
M Iu
MIu
Martynov
A N
AN
Boĭko
P R
PR
Kamchatnov
A A
AA
Kabanov
A N
AN
Iasamanova
I A
IA
Shchukin
T I
TI
Kolesnikova
V I
VI
Chubykin
A P
AP
Glukhareva
E I
EI
Gusev
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D003566:Cytidine Diphosphate Choline / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D020521:Stroke / Q000188:drug therapy* / Q000503:physiopathology
D018696:Neuroprotective Agents; D003566:Cytidine Diphosphate Choline