Unilateral lymphadenopathy due to the use of granulocyte colony stimulating factor.
A 36-year-old woman was admitted to our hospital after modified radical mastectomy operation. Adjuvant chemotherapy was administered using TAC regimen. Severe neutropenia occurred after chemotherapy. Granulocyte colony stimulating factor (G-CSF) was given to treat neutropenia. On the second day of G-CSF use, the patient complained of swelling of her neck on the left side, which subsided spontaneously after discontinuation of G-CSF medication. However, the same symptom recurred following G-CSF use on the second cycle of chemotherapy. B-mode ultrasound showed swollen lymph nodes and biopsy revealed no evidence of metastasis. Therefore, the unilateral lymphadenopathy is considered to be the side effect of G-CSF, which is very rare.
Oncology Department, Tangdu Hosptial, Xi'an, China.
Ning
N
Zhang
Jie
J
Min
Feng Xiao
FX
Huang
Fei
F
Lan
Lili
L
Liu
Helong
H
Zhang
D000328:Adult; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery; D005260:Female; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000009:adverse effects*; D006801:Humans; D008206:Lymphatic Diseases / Q000139:chemically induced*; D009503:Neutropenia / Q000188:drug therapy / Q000209:etiology
D016178:Granulocyte-Macrophage Colony-Stimulating Factor