Successful treatment of acute mania and perineal abscess using dexmedetomidine sedation as adjunctive therapy.
Acute psychiatric illness with agitation presents the clinician with a dangerous, potentially life-threatening situation often requiring complex management. Alteration in patients' insight and judgment may result in medication non-compliance, potentially further complicating therapy directed at the primary psychiatric illness as well as any co-existing conditions. Sedation is often necessary to control dangerous behaviour during the period of antipsychotic and mood-stabilising drug titration. Dexmedetomidine is a centrally acting selective α2-adrenergic agonist with anaesthetic and sedative properties widely used in intensive care units for sedation in critically ill patients. The authors report the case of a patient managed successfully with dexmedetomidine sedation while being treated for acute mania and perineal abscess.
Department of Medicine, Keesler Air Force Hospital, Keesler AFB, Mississippi, United States.
Adam L
AL
Ackerman
Cristin
C
Mount
D000038:Abscess / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000175:diagnosis / Q000188:drug therapy*; D020927:Dexmedetomidine / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D008297:Male; D055118:Medication Adherence; D012002:Rectal Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D014463:Ultrasonography
D000900:Anti-Bacterial Agents; D014150:Antipsychotic Agents; D006993:Hypnotics and Sedatives; D020927:Dexmedetomidine