A case of mediastinal seminoma presenting as superior vena cava syndrome.
Primary mediastinal seminoma is a rare tumor usually with nonspecific symptoms such as chest pain, dyspnea and hoarseness, but superior vena cava syndrome (SVCS) is an extremely uncommon syndrome. We report a 25-year-old man who presented with superior vena cava syndrome for 1 month and a 1-week history of retrosternal chest pain. Thorax computerized tomography demonstrated a soft tissue mass in the anterior mediastinum with stippled calcifications compressing the superior vena cava and other major vessels. Transthoracic biopsy showed primary seminoma of the anterior mediastinum. Combined chemoradiotherapy was performed and the patient was considered to have a partial response to treatment.
Shandong Province Qianfoshan Hospital, Shandong University, Shandong 250014, China.
Xue
X
Xu
Chengtao
C
Sun
Lei
L
Zhang
Jiangjiu
J
Liang
D000328:Adult; D059248:Chemoradiotherapy; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D018239:Seminoma / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D013479:Superior Vena Cava Syndrome / Q000209:etiology*