The impact of the Uighur medicine abnormal savda munziq on antitumor and antioxidant activity in a S180 and Ehrlich ascites carcinoma mouse tumor model.
OBJECTIVE
This study was designed to study the antitumor and antioxidant activity of Uighur medicine abnormal savda munziq (ASMq) in the S180 and Ehrlich ascites carcinoma mice tumor model.


METHODS
The serum levels of superoxide dismutase (SOD), malonaldehyde (MDA), and glutathione-catalase (GSH-PX) were analyzed, and the mice were also subjected to a hypoxia tolerance test. Their climbing ability was also analyzed.


RESULTS
The findings of the study revealed that ASMq-treatment leads to an increase in blood serum SOD and GSH-PX levels but a decrease in blood serum MDA levels. Moreover, ASMq-treatment enhanced the survival time of mice maintained under hypoxic conditions and improved their mice climbing ability.


CONCLUSIONS
The results of this study indicate that ASMq has obvious antitumor and antioxidative effects.
Department of Drug Analysis, Xinjiang Medical University, 830011 Urumqi, Xinjiang People's Republic of China.
Ainiwaer
A
Aikemu
Abdiryim
A
Yusup
Anwar
A
Umar
Bénédicte
B
Berké
Nicholas
N
Moore
Halmurat
H
Upur