Direct synthesis of metal oxide incorporated mesoporous SBA-15, and their applications in non-enzymatic sensing of glucose.
One-step direct synthetic route is reported for the preparation of M-SBA-15 materials (M=Cu, Ni, Co, Fe, and Mn) with nSi/nM ratios ranging from 100 to 10 under mild acidic condition than conventionally employed for the synthesis of Si-SBA-15. Materials were characterized by a complementary combination of X-ray diffraction, nitrogen sorption, scanning electron microscopy, transmission electron microscopy, Fourier transform infrared, and UV-visible spectroscopy. Experimental evidences show that metal oxides are incorporated in the pore wall of SBA-15 matrices. A non-enzymatic electrochemical sensor device was fabricated for glucose detection based on M-SBA-15 materials. Cyclic voltammetry and linear sweep voltammetry were used to evaluate the catalytic activity of the M-SBA-15 modified electrode toward glucose. It was found that the Cu-SBA-15 (Si/Cu=20) modified electrode showed enhanced electrocatalytic activity toward the oxidation of glucose in alkaline solution compared to that of the conventional CuO and other M-SBA-15 materials investigated in this study. Under the optimal detection conditions, the Cu-SBA-15 (Si/Cu=20) exhibited linear behavior in the concentration range from 10 μM to 20 mM for the quantification of glucose with a limit of detection of 10 μM. Moreover, the Cu-SBA-15 modified electrode was also relatively insensitive to commonly interfering species such as ascorbic acid, uric acid, and dopamine.
Department of Chemistry, Indian Institute of Technology Ropar, Rupnagar 140 001, India.
M U
MU
Anu Prathap
Balwinder
B
Kaur
Rajendra
R
Srivastava
D004563:Electrochemistry / Q000379:methods*; D004566:Electrodes; D005947:Glucose / Q000032:analysis*; D057230:Limit of Detection; D019216:Metals, Heavy / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D010084:Oxidation-Reduction; D010087:Oxides; D053838:Scattering, Small Angle; D012822:Silicon Dioxide / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
D019216:Metals, Heavy; D010087:Oxides; C509969:SBA-15; D012822:Silicon Dioxide; D005947:Glucose