One pot, two phases: iron-catalyzed cyclopropanation with in situ generated diazomethane.
Tamed! The safe handling of diazomethane can be accomplished by a two-phase reaction. After being generated in aqueous media, the highly reactive species transfers to the organic phase and directly converts alkenes into cyclopropanes (see scheme). An air-stable iron(III) porphyrin complex serves as the catalyst.
Georg-August-Universität Göttingen, Tammannstrasse 2, 37077 Göttingen, Germany.
Johannes
J
Kaschel
Tobias F
TF
Schneider
Daniel B
DB
Werz