[In vitro activity of crude extracts of two plant species in the Cerrado on yeast of the Candida SPP variety].
This work aims to evaluate the activity of Lafoensia Pacari and Brossimum gaudichaudii on yeast of the Candida variety isolated from vaginal mucus. The yeasts were obtained from swabs of women with or without symptoms. Susceptibility testing in duplicate was carried out for 34 strains of Candida compared to crude extracts of plant species at concentrations of 50, 100 and 200 mg.mL⁻¹. Extracts that produced inhibition zones with an average of over 10 mm were considered to be active. Antifungal activity of B. gaudichaudii at a concentration of 200-mg.mL⁻¹ was proven, while that of L. pacari was found to be active at 50 mg.mL⁻¹. The activity of plant extracts was revealed compared to Nystatin cream (100.000UI/4g) used for control purposes.
Fundação Universidade Federal do Tocantins, 77001-090 Palmas, TO. propesq@uft.edu.br
Sônia Maria Ferreira
SM
Queiroz e Silva
Sandra Maria Botelho
SM
Pinheiro
Maria Vilian Ferreira
MV
Queiroz
Maria Cristina
MC
Pranchevicius
José Gerley Díaz
JG
Castro
Michele Cezimbra
MC
Perim
Solange Cristina
SC
Carreiro
D002175:Candida / Q000187:drug effects*; D045424:Complex Mixtures / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*
D045424:Complex Mixtures; D010936:Plant Extracts