Newly described clinical and immunopathological feature of dermatitis herpetiformis.
Dermatitis herpetiformis (DH) is an inflammatory cutaneous disease with typical histopathological and immunopathological findings clinically characterized by intensely pruritic polymorphic lesions with a chronic-relapsing course. In addition to classic clinical manifestations of DH, atypical variants are more and more frequently reported and histological and immunological are added to them, whereas the impact on quality of life of patients with DH is increasingly important to a certain diagnosis. The aim of this paper is to describe all the possible clinical, histological, and immunological variants of DH in order to facilitate the diagnosis of a rare disease and, therefore, little known.
Department of Critical Care, Section of Dermatology, University of Florence, Piazza Indipendenza 11, 50129 Florence, Italy. vbonciolini@gmail.com
Veronica
V
Bonciolini
Diletta
D
Bonciani
Alice
A
Verdelli
Antonietta
A
D'Errico
Emiliano
E
Antiga
Paolo
P
Fabbri
Marzia
M
Caproni
D003874:Dermatitis Herpetiformis / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D006801:Humans