Multidrug-resistant Acinetobacter baumannii infection in children.
Acinetobacter baumannii is a Gram-negative coccobacillus causing serious nosocomial infections. The recent emergence of strains of bacteria, which are resistant to common antibiotics, has made the treatment of these infections increasingly complex. We report the case of a young patient affected by AIDS, who suffered brain toxoplasmosis and sepsis due to multidrug-resistant A baumannii. This bacterial infection was successfully treated with colistin and tigecycline. In addition, we review recent literature on this topic, from the year 2000 to date.
University Department of Pediatrics, Ospedale Pediatrico Bambino Gesù, Rome, Italy. maiadeluca@gmail.com
Maia
M
De Luca
Giulia
G
Angelino
Francesca Ippolita
FI
Calò Carducci
Alessandra
A
Martino
Stefania
S
Bernardi
Paola
P
Bernaschi
Michaela
M
Carletti
Patrizia
P
D'Argenio
Paolo
P
Palma
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D000151:Acinetobacter Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D040981:Acinetobacter baumannii / Q000302:isolation & purification; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019380:Anti-HIV Agents / Q000627:therapeutic use; D002648:Child; D003091:Colistin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D024901:Drug Resistance, Multiple, Bacterial; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008911:Minocycline / Q000031:analogs & derivatives / Q000627:therapeutic use; D000078304:Tigecycline; D014057:Tomography, X-Ray Computed
D000900:Anti-Bacterial Agents; D019380:Anti-HIV Agents; D000078304:Tigecycline; D008911:Minocycline; D003091:Colistin