[Distal polyneuropathy in children with diabetes mellitus type 1].
To identify the association between distal peripheral neuropathy (DPN) and type 1 diabetes mellitus (T1D), 62 children and adolescents with different duration of T1D have been studied using electromyography (EMG). Subclinical symptoms of DPN occur with equal frequency in 74% of children with short duration of T1D (group 1) and in 72% of children with long duration of disease. In both groups, the highest frequency of disturbances of the neurophysiological parameters was found in the sural sensory nerve and the lowest frequency in the median motor nerve. Correlations between HbAlc levels and compound muscle action potential were revealed only in tibial and peroneal nerves and only in the early stages of T1D. However, this dependence disappears with increasing duration of the disease.
N Iu
NIu
Lotosh
O A
OA
Lineva
I E
IE
Volkov
Z M
ZM
Mutalova
S V
SV
Savel'ev
A A
AA
Selishcheva
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications* / Q000503:physiopathology*; D003929:Diabetic Neuropathies / Q000097:blood / Q000175:diagnosis*; D004576:Electromyography; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D010543:Peroneal Nerve / Q000503:physiopathology*; D013497:Sural Nerve / Q000503:physiopathology*; D013979:Tibial Nerve / Q000503:physiopathology*
D006442:Glycated Hemoglobin