Autoimmune polyglandular syndrome: an unusual presentation with empty sella, premature ovarian failure, and Hashimoto's thyroiditis associated with thyroid cancer.
Autoimmune polyglandular syndromes are rare disorders characterized by failure of several endocrine glands, as well as non-endocrine organs, associated with immune-mediated tissue destruction. We report a rare case of polyglandular syndrome type II in a patient who presented with premature ovarian failure, Hashimoto's thyroiditis and empty sella associated with a diagnosis of differentiated thyroid carcinoma. This case probably represents the first report on this tumor in a patient with polyglandular disorder.
Department of Neuroendocrinology, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil. caroleaes@ufcspa.edu.br
Carolina Garcia Soares
CG
Leães
Maria Carolina
MC
Rios
Juliana Pereira
JP
Passaglia
Julia Fernanda
JF
Pereira-Lima
Miriam da Costa
Mda C
Oliveira
D000328:Adult; D002277:Carcinoma / Q000150:complications* / Q000601:surgery; D004652:Empty Sella Syndrome / Q000209:etiology; D005260:Female; D050031:Hashimoto Disease / Q000209:etiology; D020249:Hormone Replacement Therapy; D006801:Humans; D016884:Polyendocrinopathies, Autoimmune / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology*; D016649:Primary Ovarian Insufficiency / Q000209:etiology; D013964:Thyroid Neoplasms / Q000150:complications* / Q000601:surgery; D013965:Thyroidectomy / Q000009:adverse effects; D016896:Treatment Outcome