Topical treatment modalities for old world cutaneous leishmaniasis: a review.
Diagnosis and therapy of cutaneous leishmaniasis (CL) can be difficult             due to the variability of the clinical pictures and resistance to therapy. There is no             vaccine currently available for CL. The aim of the present review is to describe             different topical treatment modalities for old world CL. The mainstays of treatment             for old world CL are pentavalent antimony compounds which are administered             parenterally or intralesionally. New topical treatment alternatives have been available             within the past few years. Amongst several treatments used topically, physical             therapies including cryotherapy, heat therapy and CO2 laser are promising for the             treatment of old world CL. Along with that, other randomized placebo controlled             trials should be designed to find new effective therapeutic regimens.
Research Centre for Infectious Diseases and Tropical Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
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R
Alavi-Naini
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A
Fazaeli
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O'Dempsey
D000287:Administration, Topical; D000563:Amebicides / Q000008:administration & dosage; D006801:Humans; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy* / Q000628:therapy
D000563:Amebicides