The Effect of Labisia pumila var. alata on Postmenopausal Women: A Pilot Study.
This is a randomized, double-blind, placebo-controlled study comparing the effects of a water extract of Labisia pumila var. alata at 280 mg/day with placebo, given for 6 months in postmenopausal Malay women. There were 29 patients treated with Labisia pumila and 34 patients in the placebo group. Menopausal symptoms were assessed at baseline and at 6 months. The blood pressure, body mass index, waist circumference, fasting blood sugar, lipid profile, and hormonal profile (follicle stimulating hormone/luteinizing hormone/estradiol) were measured during visits every two months. ANCOVA model analysis showed significantly lower triglycerides levels in LP subjects at 6 months after treatment as compared to placebo (1.4 versus 1.9 mmol/L; adj. mean difference 0.5, 95% CI: 0.02, 0.89 after adjusted for the baseline values, age, BMI, and duration of menopause placebo). Other parameters in both groups did not differ significantly. In conclusion, daily intake of Labisia pumila at 280 mg/day for six months was found to provide benefit in reducing the triglyceride (TG) values.
School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, 16150 Kelantan, Malaysia.
Azidah
A
Abdul Kadir
Nik Hazlina
NH
Nik Hussain
Wan Mohammad
WM
Wan Bebakar
Dayang Marshitah
DM
Mohd
Wan Mohd Zahiruddin
WM
Wan Mohammad
Intan Idiana
II
Hassan
Norlela
N
Shukor
Nor Azmi
NA
Kamaruddin
Wan Nazaimoon
WN
Wan Mohamud