Hepatoid pancoast tumor. A case report and review of the literature.
A 48-year-old male patient presented with a Pancoast tumor of the right lung and a serum alpha-fetoprotein (αFP) at 39,000 ng/ml. Alpha-fetoprotein is a tumor marker found elevated in patients with hepatocellular carcinoma (HCC), germ cell or stromal tumors of the ovary and nonseminomatous testicular cancer. Occasionally, this tumor marker may rise in non-neoplastic conditions such as cirrhosis and hepatitis and only exceptionally in rare cancers with hepatoid differentiation. We present our case report and review the English literature for αFP-producing lung carcinomas. To the best of our knowledge this is the first report in the literature of an αFP producing Pancoast tumor.
Second Department of Internal Medicine Propaedeutic, Medical Oncology Unit, Attikon University Hospital, Athens, Greece.
Georgios
G
Papatsimpas
Konstantinos
K
Kamposioras
Kallirroi
K
Goula
Kleio
K
Papaparaskeva
Stelios
S
Loukides
Christophoros
C
Kotoulas
Nikolaos
N
Kelekis
Nikolaos
N
Xiros
Dimitrios
D
Pectasides
Anna
A
Koumarianou
D000230:Adenocarcinoma / Q000175:diagnosis / Q000378:metabolism*; D014408:Biomarkers, Tumor / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D010178:Pancoast Syndrome / Q000175:diagnosis / Q000378:metabolism*; D000509:alpha-Fetoproteins / Q000096:biosynthesis*
D014408:Biomarkers, Tumor; D000509:alpha-Fetoproteins