Left heart morphology and function in primary aldosteronism.
Primary aldosteronism is the most frequent cause of secondary hypertension, accounting for up to 11% of cases in selected populations. Patients affected by primary aldosteronism have shown higher prevalence of cardiovascular and cerebrovascular events compared with patients with essential hypertension, despite similar blood pressure levels. Several studies have been performed over past years aiming to explain these data; many of these evaluated echocardiographic differences in hypertension-related cardiac organ damage between primary aldosteronism and essential hypertension. This article summarizes the present knowledge about structural and functional alteration of the human left heart in primary aldosteronism.
Department of Medicine and Experimental Oncology, Division of Internal Medicine, Hypertension Unit, University of Turin, Turin, Italy.
Alberto
A
Milan
Corrado
C
Magnino
Ambra
A
Fabbri
Michela
M
Chiarlo
Giulia
G
Bruno
Isabel
I
Losano
Franco
F
Veglio
D000818:Animals; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications*; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D016277:Ventricular Function, Left