Chromatographic determination of hydrophobicity of dialkylimidazolium ionic liquids using selected stationary phase.
The determination of hydrophobicity of ionic liquids (ILs) is essential for the reason that some of these salts' classes are of toxic character. The conventional shake flask method of logP estimation fails in case of ILs. This is connected with their ionic character. Therefore other methods need to be developed and optimized. Chromatographic methods seem to be the proper ones. For that reason, several specific stationary phases (octadecyl, octyl, aminopropyl, alkylamide, cholesterolic, immobilized artificial membrane, phenyl) have been used for the determination of logk(w)  of alkylimidazolium ILs. Then, logk(w)  were used for the correlation with calculated logP for ILs. Depending on applied calculation procedure, high values of determination coefficient were obtained for alkyl-based silica stationary phases or for more specific column packing. This result is very promising as it has already been proven that several, different in nature, stationary phases can be successfully used for estimation of logP of IL cations.
Chair of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Toruń, Poland.
Sylwia
S
Studzińska
Bogusław
B
Buszewski