Permanent haemichorea associated with transient hyperglycemia.
Hyperglycemia is associated with several common neurological syndromes. Chorea, however, is a rare association that has only been documented in the literature recently. The triad of chorea, non-ketotic hyperglycemia and a high signal basal ganglia lesion on the T1 weighted brain MRI (C-H-BG) is considered to be a unique syndrome. C-H-BG refers to the onset of chorea during or shortly after (days to weeks) an episode of non-ketotic hyperglycemia. There is usually a high signal lesion in the basal ganglia on T1 weighted brain MRI that corresponds to the location of the chorea. Most case reports of C-H-BG have been described in Asians. C-H-BG is considered to be a benign condition in which the clinical and MRI signs resolve quickly upon correction of blood glucose levels. Here, the authors describe a case of C-H-BG in a middle aged Caucasian in whom the chorea did not resolve with improved glycemic control.
Department of Medicine, University of Alberta, Edmonton, Canada.
Hannah
H
Slabu
Sheila
S
Savedia-Cayabyab
Peter
P
Senior
Terra
T
Arnason
D002819:Chorea / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D003937:Diagnosis, Differential; D018492:Dopamine Antagonists / Q000627:therapeutic use; D006801:Humans; D006943:Hyperglycemia / Q000150:complications* / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018967:Risperidone / Q000627:therapeutic use
D018492:Dopamine Antagonists; D007004:Hypoglycemic Agents; D018967:Risperidone