Label-free sensing of pH and silver nanoparticles using an "OR" logic gate.
Many natural phenomena are associated with the presence of two or more separate variables. We report here an "OR" DNA logic gate based on a luminescent platinum(II) switch-on probe for silver nanoparticles and pH, both of which may be considered putative indicators of pollution. The modulation of metal complex/double-stranded DNA complex phosphorescence by Ag(+) and H(+) was used to construct a simple, rapid and label-free method for the label-free detection of pH and nanomolar Ag(+) ions and nanoparticles in aqueous solutions with high selectivity.
Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. edmondma@hkbu.edu.hk
Dik-Lung
DL
Ma
Hong-Zhang
HZ
He
Victor Pui-Yan
VP
Ma
Daniel Shiu-Hin
DS
Chan
Ka-Ho
KH
Leung
Hai-Jing
HJ
Zhong
Lihua
L
Lu
Jean-Louis
JL
Mergny
Chung-Hang
CH
Leung
D001483:Base Sequence; D002414:Cations, Monovalent / Q000032:analysis; D004247:DNA / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D049408:Luminescent Agents / Q000737:chemistry*; D008163:Luminescent Measurements / Q000379:methods*; D053758:Nanoparticles / Q000032:analysis*; D009944:Organoplatinum Compounds / Q000737:chemistry*; D012680:Sensitivity and Specificity; D012834:Silver / Q000032:analysis*
D002414:Cations, Monovalent; D049408:Luminescent Agents; D009944:Organoplatinum Compounds; D012834:Silver; D004247:DNA