Stem cells assessed.
The increasing momentum of stem cell research continues, with the better characterization of induced pluripotent stem (iPS) cells, the conversion of differentiated cells into different cell types and the use of pluripotent stem cells to generate whole tissues, among other advances. Here, six experts in the field of stem cell research compare different stem cell models and highlight the importance of pursuing complementary experimental approaches for a better understanding of pluripotency and differentiation and an informed approach to medical applications.
Walloon Excellence in Life Science and Biotechnology, Interdisciplinary Research Institute, Université Libre de Bruxelles, 808, route de Lennik, BatC, C6-130, 1070 Brussels, Belgium. Cedric.Blanpain@ulb.ac.be
Cédric
C
Blanpain
George Q
GQ
Daley
Konrad
K
Hochedlinger
Emmanuelle
E
Passegué
Janet
J
Rossant
Shinya
S
Yamanaka
D000818:Animals; D001675:Bioethics; D002454:Cell Differentiation; D053595:Embryonic Stem Cells / Q000166:cytology*; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology*; D051379:Mice; D008954:Models, Biological; D020411:Oligonucleotide Array Sequence Analysis; D057905:Stem Cell Research; D013234:Stem Cells / Q000166:cytology*