An approach to the management of hyperbilirubinemia in the preterm infant less than 35 weeks of gestation.
We provide an approach to the use of phototherapy and exchange transfusion in the management of hyperbilirubinemia in preterm infants of <35 weeks of gestation. Because there are limited data for evidence-based recommendations, these recommendations are, of necessity, consensus-based. The recommended treatment levels are based on operational thresholds for bilirubin levels and represent those levels beyond which it is assumed that treatment will likely do more good than harm. Long-term follow-up of a large population will be needed to evaluate whether or not these recommendations should be modified.
Division of Newborn Medicine, Department of Pediatrics, Oakland University William Beaumont School of Medicine, Beaumont Children's Hospital, Royal Oak, MI 48073, USA. jmaisels@beaumont.edu
M J
MJ
Maisels
J F
JF
Watchko
V K
VK
Bhutani
D K
DK
Stevenson
D001663:Bilirubin / Q000502:physiology; D005078:Exchange Transfusion, Whole Blood; D006801:Humans; D051556:Hyperbilirubinemia, Neonatal / Q000503:physiopathology / Q000628:therapy*; D052577:Infant, Extremely Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000628:therapy*; D010789:Phototherapy
D001663:Bilirubin