Spontaneous coronary thrombosis following thrombolytic therapy for acute cardiovascular accident and stroke: a case study.
Cardiac complications following stroke or acute cerebrovascular accidents (CVA) are common; however, many of these complications are asymptomatic and do not cause adverse cardiac effects. Symptomatic events (such as acute myocardial infarction after CVA) rarely occur and are often the result of an underlying cardiac embolic source, such as a left ventricular thrombus. We report a case of spontaneous coronary thrombosis following thrombolytic therapy for acute CVA, and discuss the implication that an underlying systemic pro-thrombotic state may predispose individuals to thrombosis in disparate vascular beds.
Division of Cardiovascular Medicine, The Gill Heart Institute, University of Kentucky, The Lexington VA Medical Center, 900 S. Limestone Street, 326 CTW Building, Lexington, KY 40536-0200, USA. eric.wallace@uky.edu
Eric L
EL
Wallace
Susan S
SS
Smyth
D000208:Acute Disease; D000368:Aged; D003324:Coronary Artery Disease / Q000209:etiology*; D003328:Coronary Thrombosis / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D020521:Stroke / Q000150:complications / Q000188:drug therapy*; D015912:Thrombolytic Therapy / Q000009:adverse effects*