Survival of patients with portal vein thrombosis: analysis based on disease onset.
OBJECTIVE
To identify prevalent causes and determine survival rates of patients with portal vein thrombosis (PVT) in the Western Saudi Arabia.


METHODS
Retrospective chart review of patients diagnosed with chronic liver disease and portal vein thrombosis in two major cities in Western Saudi Arabia during the period 2000-2009.


RESULTS
Among 1349 patients screened, 109 patients met the inclusion criteria, 67 patients had acute PVT and 42 patients had chronic PVT. The relative risk of developing PVT is higher in males in whom acute PVT is 1.32 vs. 0.68 in females (95% CI: 090-1.94). Mean survival age of acute and chronic PVT (Kaplan-Meier) is 5.61 years (95% CI: 4.52-6.70). Univariate and multivariate regression analysis identified several variables in which international normalized ratio (INR) level on presentation was found to be a significant variable in survival.


CONCLUSIONS
Mean survival for acute or chronic PVT is about five years. The first determination of INR level is a useful predictor of survival.
Department of Medicine, Umm AlQura University, Makkah, Saudi Arabia. yasirkhayyat@hotmail.com
Yasir Mohammed
YM
Khayyat
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D019934:International Normalized Ratio; D008297:Male; D008875:Middle Aged; D011169:Portal Vein; D012189:Retrospective Studies; D020246:Venous Thrombosis / Q000188:drug therapy / Q000209:etiology / Q000401:mortality*