Subacute motor axonal neuropathy associated with the IgG anti-GalNAc-GD1a antibody.
A 14-year-old boy developed a distinct asymmetrical muscle atrophy and weakness with no sensory disturbance in the lower extremities after enteritis. He had an elevated titre of the IgG antibody against GalNAc-GD1a, but none of the others. A nerve conduction study revealed motor axonopathy. Intravenous immunoglobulin therapy improved the status gradually, with low titres of IgG anti-GalNAc-GD1a.
Department of Neurology, Arita Kyouritsu Hospital, Sage, Japan. goto@kyouritsu-hp.arita.saga.jp
Hirofumi
H
Goto
Takayasu
T
Fukudome
Susumu
S
Kusunoki
Hidenori
H
Matsuo
D000293:Adolescent; D001369:Axons; D005732:Gangliosides / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008297:Male; D009422:Nervous System Diseases / Q000276:immunology*
D005732:Gangliosides; D007074:Immunoglobulin G; C055253:IV(4)-galactosyl-N-acetylganglioside GD1a