Palladium(II)-catalyzed direct alkenylation of nonaromatic enamides.
A mild and efficient method for the direct alkenylation of nonaromatic enamides was achieved through a palladium(II)-catalyzed C-H functionalization. The reaction scope includes cyclic and acyclic enamides and a range of activated alkenes. This approach represents the first successful direct C(3)-functionalization of nonaromatic cyclic enamides.
Institut de Chimie Organique et Analytique, UMR 7311 CNRS, rue de Chartres, Université d'Orléans, F-45067 Orléans Cedex 2, France.
Nicolas
N
Gigant
Isabelle
I
Gillaizeau
D000478:Alkylation; D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D000577:Amides; D009942:Organometallic Compounds; D010165:Palladium