Chemical constituents from the roots of Periploca sepium with insecticidal activity.
Five compounds were isolated from the root powder of Periploca sepium. By mainly HR-ESI-MS, (1)H, (13)C, and 2D NMR spectral data, they were characterized as periplocoside X (1), oligasaccharide A (2), periplocoside A (3), periplocoside E (4), and periplocoside N (5), respectively. Compounds 1-5 were found to possess insecticidal activities against the red imported fire ant. Among the compounds, periplocoside X showed significant activity with LD(50) values of 748.99, 116.62, 2169.58, and 3079.33mg/l against soldiers, workers, males, and alate females of red imported fire ant, respectively.
The Ministry of Education Key Laboratory of Pesticide and Chemical Biology, South China Agricultural University, Guangzhou 510642, China.
Yan
Y
Li
Xin-Nian
XN
Zeng
Wen-Zhong
WZ
Wang
Cai-Hong
CH
Luo
Qin
Q
Yan
Meng
M
Tian
D000818:Animals; D001000:Ants / Q000187:drug effects*; D005260:Female; D006027:Glycosides; D007306:Insecticides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D007928:Lethal Dose 50; D008297:Male; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009844:Oligosaccharides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D031109:Periploca / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D011283:Pregnenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
D006027:Glycosides; D007306:Insecticides; D009844:Oligosaccharides; D011283:Pregnenes; C509135:periplocoside E; C576105:periplocoside X; C056990:periplocoside A