Coexistence of fibrillary glomerulonephritis in a patient with multiple myeloma.
A 71-year-old man was admitted to our hospital for two weeks due to edema in both legs. A bone marrow aspiration test confirmed a diagnosis of multiple myeloma. The result of the patient's renal biopsy showed fibrillary glomerulonephritis (FGN). FGN is a rare form of glomerulopathy that is diagnosed using electron microscopy when deposits of amyloid-like fibrils are observed on the mesangium and microvascular wall. These fibrils do not respond to Congo red staining and are generally 12-30 nm in diameter. This is a report of an unusual case of fibrillary glomerulonephritis in a patient with multiple myeloma.
Department of Internal Medicine, Kosin University College of Medicine, Korea.
Jin Hee
JH
Park
Bo Ra
BR
Kim
Bong Geon
BG
Chun
Mi Hyang
MH
Kim
Ho Sik
HS
Shin
Yeon Soon
YS
Jung
Hark
H
Rim
D000368:Aged; D005920:Glomerular Mesangium / Q000098:blood supply / Q000276:immunology / Q000473:pathology; D005921:Glomerulonephritis / Q000150:complications* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000378:metabolism; D007146:Immunoglobulin lambda-Chains / Q000378:metabolism; D007150:Immunohistochemistry; D008297:Male; D046529:Microscopy, Electron, Transmission; D009101:Multiple Myeloma / Q000150:complications* / Q000276:immunology / Q000473:pathology
D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains