Cystic mucinous tumors of the urachus:  carcinoma in situ or adenoma of unknown malignant potential?
Mucinous cystadenocarcinomas of the urachus are rare.  Mucinous benign or premalignant tumors are even rarer, yet pose a challenge in diagnosis and management.  We report a case of a 66-year-old man with lower abdominal pain who had a large cystic tumor at the dome of the bladder.  En-bloc resection of the tumor with partial cystectomy revealed mucinous cystadenocarcinoma in situ.  We reviewed the characteristics of all seven previously reported cases.  These tumors are pre-malignant and can cause significant morbidity and mortality.  They need to be treated similar to conventional mucinous cystadenocarcinoma by wide surgical resection and partial cystectomy.
Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
Akl C
AC
Fahed
Daisuke
D
Nonaka
Jamie A
JA
Kanofsky
William C
WC
Huang
D000368:Aged; D002278:Carcinoma in Situ / Q000473:pathology* / Q000601:surgery; D018282:Cystadenocarcinoma, Mucinous / Q000473:pathology* / Q000601:surgery; D018291:Cystadenoma, Mucinous / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D014497:Urachus / Q000473:pathology* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000601:surgery