Muscle velocity recovery cycles: effects of repetitive stimulation on two muscles.
BACKGROUND
We sought to characterize the excitability properties of tibialis anterior (TA) and brachioradialis (BR) muscles at rest and during electrically induced muscle activation in normal subjects.


METHODS
Two centers recruited 10 subjects each. Multi-fiber velocity recovery cycles (VRCs) were recorded from TA (both centers) and BR (one center). VRCs were assessed at rest and during repetitive stimulation (intermittent 20 Hz for 6 min). Changes in latency and peak amplitude of the muscle action potential induced by a frequency ramp to 30 Hz were also characterized.


RESULTS
Excitability properties recorded from TA were very similar between centers. Repetitive stimulation generated marked excitability changes, which were similar between TA and BR.


CONCLUSIONS
Standardized tests of muscle VRCs and responses to repetitive stimulation can provide consistent measures of membrane function and may encourage their wider use in clinical neurophysiology to investigate the pathophysiology of neuromuscular disorders.
Department of Neurology, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Delphine
D
Boërio
Werner J
WJ
Z'Graggen
S Veronica
SV
Tan
Andri
A
Guetg
Karin
K
Ackermann
Hugh
H
Bostock
D000200:Action Potentials / Q000502:physiology*; D000328:Adult; D000368:Aged; D004558:Electric Stimulation / Q000379:methods; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000502:physiology*