A patient with primary Burkitt's lymphoma of the postnasal space: case report.
BACKGROUND
Burkitt's lymphoma is a highly aggressive lymphoma. The endemic form is present with Epstein - Barr virus. The most common sites are the mandible, facial bones, kidneys, gastrointestinal tract, ovaries, breast and extra-nodal sites. We present the first reported case of a primary Burkitt's lymphoma of the postnasal space occurring in an elderly Caucasian male.


METHODS
A 72-year-old Caucasian male farmer presented with a 6-week history of a productive cough and a painless left sided cervical swelling. Examination of the neck revealed a 5 cm by 5 cm hard mass in the left anterior triangle. A CT scan of the head and neck showed a soft tissue swelling in the postnasal space. Histology of the postnasal space mass showed squamous mucosa infiltrated by a high grade lymphoma. Immunohistochemical staining and in situ hybridisation confirmed the tumour to be Epstein - Barr virus Ribonucleic acid negative suggesting this was a rare sporadic form of the tumour presenting in a location that is atypical for the clinical subtype and age of the patient.


CONCLUSIONS
This is the first reported case of sporadic Burkitt's lymphoma of the postnasal space of an elderly Caucasian male in the absence of Epstein - Barr virus or human immunodeficiency virus infection and further serves to illustrate the diversity of histological subtypes of malignancies that may develop at this concealed site.
Department of Head and Neck Surgery, Chase Farm & Barnet NHS Trust, Enfield, UK. mrtupile@yahoo.com
Tahwinder
T
Upile
Waseem
W
Jerjes
Jesuloba
J
Abiola
Panagiotis
P
Kafas
Ann
A
Sandison
Zaid
Z
Hamdoon
Mohammed
M
Al-Khawalde
Hani
H
Radhi
D000368:Aged; D002051:Burkitt Lymphoma / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D017403:In Situ Hybridization; D008297:Male