Pancreatic Adenocarcinoma, version 2.2012: featured updates to the NCCN Guidelines.
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Pancreatic Adenocarcinoma discuss the workup and management of tumors of the exocrine pancreas. These NCCN Guidelines Insights provide a summary and explanation of major changes to the 2012 NCCN Guidelines for Pancreatic Adenocarcinoma. The panel made 3 significant updates to the guidelines: 1) more detail was added regarding multiphase CT techniques for diagnosis and staging of pancreatic cancer, and pancreas protocol MRI was added as an emerging alternative to CT; 2) the use of a fluoropyrimidine plus oxaliplatin (e.g., 5-FU/leucovorin/oxaliplatin or capecitabine/oxaliplatin) was added as an acceptable chemotherapy combination for patients with advanced or metastatic disease and good performance status as a category 2B recommendation; and 3) the panel developed new recommendations concerning surgical technique and pathologic analysis and reporting.
UCSF Helen Diller Family Comprehensive Cancer Center.
Margaret A
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Tempero
J Pablo
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Arnoletti
Stephen W
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Behrman
Edgar
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Ben-Josef
Al B
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Benson
Ephraim S
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Casper
Steven J
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Cohen
Brian
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Czito
Joshua D I
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Ellenhorn
William G
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Hawkins
Joseph
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Herman
John P
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Hoffman
Andrew
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Srinadh
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Komanduri
Albert
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Koong
Wen Wee
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Mokenge P
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Malafa
Nipun B
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Merchant
Sean J
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Mulvihill
Peter
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Muscarella
Eric K
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Nakakura
Jorge
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Obando
Martha B
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Pitman
Aaron R
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Sasson
Anitra
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Tally
Sarah P
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Thayer
Samuel
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Whiting
Robert A
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Wolff
Brian M
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Wolpin
Deborah A
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Freedman-Cass
Dorothy A
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Shead
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003952:Diagnostic Imaging / Q000379:methods; D006801:Humans; D009367:Neoplasm Staging; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*