[Progress in molecular diagnosis of fragile X syndrome].
Fragile X mental retardation 1 is the gene underlying fragile X syndrome (FXS). Its product, fragile X mental retardation protein, is closely involved with development of brain and neurons. PCR and Southern blotting have been the major methods for laboratory diagnosis of FXS. In this article, the progress in the molecular diagnosis of FXS is reviewed.
Department of Clinical Genetics and Experimental Medicine, Fuzhou General Hospital, Fuzhou, Fujian 350025, P. R. China.
Xiao-yan
XY
Guo
Juan
J
Liao
Feng-hua
FH
Lan
D051860:Fragile X Messenger Ribonucleoprotein 1 / Q000235:genetics; D005600:Fragile X Syndrome / Q000175:diagnosis* / Q000235:genetics*; D006801:Humans; D057089:Pathology, Molecular / Q000379:methods
D051860:Fragile X Messenger Ribonucleoprotein 1