Triterpene saponins with hyaluronidase inhibitory activity from the seeds of Camellia sinensis.
The MeOH extract of the seeds of Camellia sinensis (L.) KUNTZE gave twelve new saponins (1-12) along with ten known saponins (13-22). These saponins (1-22) showed stronger hyaluronidase inhibitory activity than the positive control, rosmarinic acid.
School of Pharmaceutical Sciences, University of Shizuoka, Shizuoka 422–8526, Japan.
Michiko
M
Myose
Tsutomu
T
Warashina
Toshio
T
Miyase
D028241:Camellia sinensis / Q000737:chemistry*; D006821:Hyaluronoglucosaminidase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D012639:Seeds / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry
D012503:Saponins; D014315:Triterpenes; D006821:Hyaluronoglucosaminidase