Direct duplication of the Y chromosome with normal phenotype - incidental finding in two cases.
Structural rearrangement in the Y chromosome is closely involved in spermatogenesis. However, several Y chromosome variants may have no deleterious effects on male reproduction. Here, we report two cases of Y chromosomal duplication from incidental findings. Their FISH analysis revealed direct duplication of large segments of short and long arms of the Y chromosome. Nearly two intact Y chromosomes were carried in these two cases with normal phenotype.
Department of Obstetrics and Gynecology, Kuo General Hospital, Tainan, Taiwan.
L-C
LC
Kuan
M-T
MT
Su
P-L
PL
Kuo
T-C
TC
Kuo
D000328:Adult; D058674:Chromosome Duplication / Q000235:genetics; D041322:Chromosomes, Human, Y / Q000235:genetics; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007231:Infant, Newborn; D059785:Karyotype; D008297:Male; D010375:Pedigree; D010641:Phenotype; D011247:Pregnancy; D012729:Sex Chromosome Aberrations; D055815:Young Adult