Acquired hemophilia in malignancy.
Acquired hemophilia is a rare but potentially morbid complication in patients with cancer. It may be seen in patients with hematologic neoplasms (usually lymphoproliferative disorders) or with solid tumors. Although the presence of an underlying malignancy portends a worse outcome, the literature suggests that the usual principles of treatment, including immunosuppression, apply to these patients. However, appropriate consideration should be given to the choice of agents, depending on individual risk factors for complications such as thrombosis and infection.
Department of Medicine, Division of Hematology/Oncology, University of North Carolina at Chapel Hill, NC, USA.
Brandi N
BN
Reeves
Nigel S
NS
Key
D006467:Hemophilia A / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D009369:Neoplasms / Q000150:complications* / Q000188:drug therapy*
D007166:Immunosuppressive Agents