New insights into rotavirus vaccines.
Rotavirus vaccines have shown to be effective and well tolerated in clinical trials. However it's crucial to point out that immunization occurs in "real-word" conditions different from ideal clinical trial settings. Thus, the impact of rotavirus vaccines in terms of effectiveness and safety needs to be evaluated in real-world conditions. Post-licensure data regarding vaccine impact, effectiveness and safety under routine use are now available and provide a "real-world view". We reviewed published data about the impact of rotavirus vaccines in the post-licensure era.
Department of Pediatrics, Luigi Sacco Hospital, University of Milan, Milan, Italy. mameli.chiara@hsacco.it
Chiara
C
Mameli
Valentina
V
Fabiano
Gian Vincenzo
GV
Zuccotti
D006801:Humans; D011358:Product Surveillance, Postmarketing; D012400:Rotavirus Infections / Q000276:immunology / Q000517:prevention & control*; D022243:Rotavirus Vaccines / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology*
D022243:Rotavirus Vaccines