[Community-acquired Staphylococcus aureus necrotizing pneumonia secreting Panton-Valentine leukocidin in an infant].
Staphylococcus aureus (SA) necrotizing pneumonia secreting Panton-Valentine leukocidin (PVL) has a high mortality rate, approximately 50% according to recent data, mainly in children and young adults. Recently, 2 cases of the disease have been reported in newborn twins with a good outcome. We report a third case of community-acquired necrotizing pneumonia due to SA sensitive to methicillin (SASM) secreting Panton-Valentine leukocidin (PVL) in an infant, initially paucisymptomatic, in the context of familial furunculosis, with a fatal outcome. Cases of necrotizing pneumonia in this age group are emerging, and extensive information for clinicians is needed due to the high mortality rate of the disease.
Service de réanimation pédiatrique et néonatale, hôpital Couple Enfant, CHU de Grenoble, boulevard de Chantourne, BP 217, 38043 Grenoble cedex 9, France. AMillet@chu-grenoble.fr
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A
Millet
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A
Desrumaux
A
A
Gayot
A
A
Tristan
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G
Emeriaud
T
T
Debillon
I
I
Wroblewski
D001427:Bacterial Toxins; D017714:Community-Acquired Infections / Q000378:metabolism / Q000473:pathology; D005098:Exotoxins / Q000378:metabolism*; D006801:Humans; D007223:Infant; D007956:Leukocidins / Q000378:metabolism*; D008297:Male; D009336:Necrosis; D011023:Pneumonia, Staphylococcal / Q000378:metabolism* / Q000473:pathology; D013211:Staphylococcus aureus
D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin