[A case of advanced primary colorectal carcinoma accompanied by liver metastasis in which ileus developed due to marked fibrosis with cicatricial formation in primary colorectal cancer treated by chemotherapy including bevacizumab].
A 64-year-old woman was introduced to our hospital with liver tumors. Our examination revealed that she had advanced colon carcinoma with multiple liver metastasis. Without symptoms from the primary cancer, she underwent chemotherapy of avastin FOLFOX. After 2 courses of chemotherapy, she suffered ileus and underwent operation. The resected specimen showed marked tumor necrosis and fibrosis, but few tumor cells remained in the primary lesion. We think this was a rare case of suffered ileus because of marked response of chemotherapy in primary colon carcinoma.
Center for Gastroenterology, Otaru Ekisaikai Hospital. kunihiro-takanashi@otaru-ekisaikai.jp
Kunihiro
K
Takanashi
Shinichi
S
Katsuki
Tomoki
T
Fujita
Eriko
E
Waga
Yuichi
Y
Shimodate
Kazuaki
K
Sasaki
Tetsufumi
T
Someya
Keisuke
K
Ohno
Masahiro
M
Fujita
D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage / Q000009:adverse effects*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D000068258:Bevacizumab; D002277:Carcinoma / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D002921:Cicatrix / Q000473:pathology; D015179:Colorectal Neoplasms / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D045823:Ileus / Q000209:etiology*; D002955:Leucovorin / Q000008:administration & dosage; D008103:Liver Cirrhosis / Q000209:etiology; D008113:Liver Neoplasms / Q000556:secondary*; D008875:Middle Aged; D009944:Organoplatinum Compounds / Q000008:administration & dosage
D061067:Antibodies, Monoclonal, Humanized; D009944:Organoplatinum Compounds; D000068258:Bevacizumab; D002955:Leucovorin; D005472:Fluorouracil