Analysis of the aetiology of diarrhoea in outpatients in 2007, Henan province, China.
The purpose of this study was to determine the aetiology of acute diarrhoea and improve knowledge of gastrointestinal pathogens in China. Faecal specimens from 1526 outpatients with diarrhoea were collected from 20 hospitals in Henan province and the prevalence of seven bacterial and five viral diarrhoeagenic pathogens were determined. Bacterial pathogens were recovered from 279/1526 (18·3%) stool specimens and viral pathogens were detected in 178/1526 (11·7%) stool specimens. The top five pathogenic species were diarrhoeagenic E. coli (n = 140, 9·2%), rotavirus (n = 79, 5·2%), Shigella spp. (n = 69, 4·5%), Salmonella spp. (n = 66, 4·3%) and norovirus (n = 56, 3·7%). The prevalence of pathogens showed correlation with age, season and clinical symptoms. Several dominant serotypes were identified in Shigella and Salmonella isolates, and high prevalence of multiple drug-resistant isolates was observed in both species. This important information will have a significant effect on public health policy development and resource prioritization practices.
China National Center for Biotechnology Development, Beijing, China.
M
M
Zhu
The National Institutes for Food and Drug Control, Beijing, China.
S
S
Cui
The National Institutes for Food and Drug Control, Beijing, China.
L
L
Lin
Henan Provincial Center for Disease Control and Prevention, China.
B
B
Xu
Henan Provincial Center for Disease Control and Prevention, China.
J
J
Zhao
Henan Provincial Center for Disease Control and Prevention, China.
S
S
Xia
Henan Provincial Center for Disease Control and Prevention, China.
W
W
Deng
Henan Provincial Center for Disease Control and Prevention, China.
Z
Z
Xie
Henan Provincial Center for Disease Control and Prevention, China.
J
J
Zhang
Chinese Center for Disease Control and Prevention, Beijing, China.
Z
Z
Wang
Chinese Center for Disease Control and Prevention, Beijing, China.
Z
Z
Feng
Chinese Center for Disease Control and Prevention, Beijing, China.
W
W
Yang
Chinese Center for Disease Control and Prevention, Beijing, China.
L
L
Ran
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D017250:Caliciviridae Infections / Q000150:complications / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D003967:Diarrhea / Q000453:epidemiology* / Q000382:microbiology* / Q000821:virology; D052978:Disk Diffusion Antimicrobial Tests; D004405:Dysentery, Bacillary / Q000150:complications / Q000453:epidemiology; D004926:Escherichia coli / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000150:complications / Q000453:epidemiology; D005243:Feces / Q000382:microbiology* / Q000821:virology; D005260:Female; D005759:Gastroenteritis / Q000150:complications / Q000382:microbiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D029322:Norovirus / Q000302:isolation & purification; D015995:Prevalence; D012401:Rotavirus / Q000302:isolation & purification; D012400:Rotavirus Infections / Q000150:complications / Q000453:epidemiology; D012475:Salmonella / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification; D012480:Salmonella Infections / Q000150:complications / Q000453:epidemiology; D012703:Serotyping; D012760:Shigella / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification; D055815:Young Adult
D000900:Anti-Bacterial Agents