Effect of dialysis type on orbital vascular flow in patients with end-stage renal disease.
OBJECTIVE
To evaluate ocular blood flow dynamics by color Doppler ultrasonography (CDU) in patients with end-stage renal disease (ESRD). Additionally, to investigate the effect of dialysis type on ocular blood flow by comparing the findings of peritoneal dialysis (PD) subjects, hemodialysis (HD) subjects, and healthy controls.


METHODS
Forty patients (21 HD and 19 PD) and 40 controls were included in the study. CDU and spectral analysis of temporal posterior ciliary artery (TPCA) and central retinal artery (CRA) were performed to evaluate peak systolic flow velocity (PSV), end diastolic flow velocity (EDV), and resistive indices (RIs). Ocular blood flows were examined before and after HD. Post-HD findings were compared with those in PD subjects and healthy controls.


RESULTS
PSV and EDV values in CRA and TPCA after HD sessions were found to be significantly decreased when compared with pre-dialysis values. There was no statistically significant difference between the pre-dialysis and post-dialysis RI values of both arteries. Systolic and diastolic blood flows in CRA and TPCA were higher and RI values were lower in PD subjects than in HD and controls. No significant difference was seen between HD subjects and controls.


CONCLUSIONS
After a single HD session, ocular blood flows of patients with ESRD were normalized. But PD subjects show higher systolic and diastolic ocular blood flows than healthy controls, suggesting that HD is more effective than PD for achieving normal ocular blood flow.
Department of Radiology, School of Medicine, Fatih University, Ankara, Turkey. drilerisoy@hotmail.com
Zeynep Ilerisoy
ZI
Yakut
Remzi
R
Karadag
Ali
A
Akcay
Nuket
N
Bavbek
Hatice
H
Akay
Asli
A
Koktener
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001783:Blood Flow Velocity / Q000502:physiology; D016022:Case-Control Studies; D019842:Ciliary Arteries / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009915:Orbit / Q000098:blood supply* / Q000000981:diagnostic imaging*; D011446:Prospective Studies; D012039:Regional Blood Flow / Q000502:physiology; D006435:Renal Dialysis / Q000379:methods*; D012161:Retinal Artery / Q000000981:diagnostic imaging* / Q000503:physiopathology; D018615:Ultrasonography, Doppler, Color