Amnesia and pain relief after cardiopulmonary resuscitation in a cancer pain patient: a case report.
The mechanism of chronic pain is very complicated. Memory, pain, and opioid dependence appear to share common mechanism, including synaptic plasticity, and anatomical structures. A 48-yr-old woman with severe pain caused by bone metastasis of breast cancer received epidural block. After local anesthetics were injected, she had a seizure and then went into cardiac arrest. Following cardiopulmonary resuscitation, her cardiac rhythm returned to normal, but her memory had disappeared. Also, her excruciating pain and opioid dependence had disappeared. This complication, although uncommon, gives us a lot to think about a role of memory for chronic pain and opioid dependence.
Department of Anesthesiology and Pain Medicine, The Catholic University of Korea, Seoul, Korea.
Jin Young
JY
Chon
Yun Jin
YJ
Hahn
Choon Ho
CH
Sung
Ho Sik
HS
Moon
D000647:Amnesia / Q000175:diagnosis*; D000772:Anesthesia, Local / Q000009:adverse effects; D001859:Bone Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D016887:Cardiopulmonary Resuscitation; D004569:Electroencephalography; D005260:Female; D006323:Heart Arrest / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008619:Mepivacaine / Q000009:adverse effects; D008875:Middle Aged; D059408:Pain Management; D012640:Seizures / Q000209:etiology; D014057:Tomography, X-Ray Computed
D008619:Mepivacaine