[Depression and risk factors in patients with Crohn's disease].
OBJECTIVE
This study was conducted to determine the risk factors among patients with depression with Crohn's disease.


METHODS
Data were collected by questionnaire from 276 patients who were diagnosed with Crohn's disease at a tertiary hospital located in Seoul. Measurements included patients' demographic characteristics, clinical characteristics, depression level, and health-related quality of life. Data were analyzed using t-test, χ²-test, Wilcoxon rank sum test, and logistic regression analyses.


RESULTS
The incidence rate of depression (BDI-II ≥ 14 scores) was 31.9% (n=88). Univariate analysis revealed that being a woman, school graduation status, economic status (low), BMI(<18.5 Kg/m²), disease duration (≥ 3 years), CDAI (≥ 150 scores), frequency of hospital admission (≥ 2), extra-intestinal manifestation (arthralgia, stomatitis), administration of 5-aminosalicylic acid, and disease related quality of life (SIBDQ<50 scores) were associated with depression. Multivariate analysis revealed that economic status (low), school graduation status, and quality of life (SIBDQ<50 scores) were more likely to report high level of depression.


CONCLUSIONS
Future research should consider managing depression as an essential component of comprehensive care for patients with Crohn's disease. In addition, further research is needed to develop strategies to better improve quality of life among patients with Crohn's disease who are depressed.
College of Nursing, Jeju National University, Jeju, Korea.
Ok-Hee
OH
Cho
Yang-Sook
YS
Yoo
Suk-Kyun
SK
Yang
D000328:Adult; D018771:Arthralgia / Q000209:etiology; D015992:Body Mass Index; D003424:Crohn Disease / Q000150:complications / Q000188:drug therapy / Q000523:psychology*; D003863:Depression; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D019804:Mesalamine / Q000627:therapeutic use; D011788:Quality of Life; D012307:Risk Factors; D012959:Socioeconomic Factors; D013280:Stomatitis / Q000209:etiology; D011795:Surveys and Questionnaires; D055815:Young Adult
D019804:Mesalamine