Ectopic bone formation in a subsegmental bronchus.
A 48-year-old man with fever and dry cough was admitted to our hospital. Imaging examinations revealed a mass lesion with calcification in the right B(3)b bronchus and atelectasis in the distal lung area. Subsequently, right S(3) segmentectomy was performed. There was a hard polypoid mass completely obstructing the right B(3)b bronchus. Histopathological findings suggested a metaplastic bone formation with mature bone marrow tissue leading to the primary bronchial cartilage. A case of ectopic bone formation in subsegmental bronchus has never been reported thus far. The resident fibroblasts might transform into osteoblasts under appropriate environmental conditions and induce bone formation.
Department of General Thoracic Surgery, Osaka City General Hospital, 2-13-22 Miyakojima Hondori, Miyakojima-ku, Osaka 534-0021, Japan. t-tsukioka@med.osaka-cu.ac.jp
Takuma
T
Tsukioka
Rhoji
R
Yamamoto
Makoto
M
Takahama
Ryu
R
Nakajima
Hirohito
H
Tada
D001706:Biopsy; D001980:Bronchi / Q000473:pathology* / Q000601:surgery; D001982:Bronchial Diseases / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D001999:Bronchoscopy; D003371:Cough / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009999:Ossification, Heterotopic / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D001261:Pulmonary Atelectasis / Q000209:etiology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome