Cardiac juvenile xanthogranuloma in an infant presenting with pericardial effusion.
Juvenile xanthogranuloma is a rare histiocytic disorder of childhood mainly affecting skin and rarely deep soft tissues and viscera. We report a 2-month-old infant who presented with respiratory distress secondary to a large pericardial effusion associated with an epicardial mass. Excisional biopsy was performed and the mass was diagnosed as juvenile xanthogranuloma. The child is well without evidence of disease 8 months following the excision. The corresponding literature on juvenile xanthogranuloma with cardiac manifestations is reviewed.
Division of Cardiology, Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, Detroit, MI 48201-2119, USA. dkobayas@dmc.org
Daisuke
D
Kobayashi
Ralph E
RE
Delius
Larisa V
LV
Debelenko
Sanjeev
S
Aggarwal
D001706:Biopsy; D006348:Cardiac Surgical Procedures; D004452:Echocardiography; D005260:Female; D006331:Heart Diseases / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D010490:Pericardial Effusion / Q000175:diagnosis / Q000209:etiology*; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology; D016896:Treatment Outcome; D014972:Xanthogranuloma, Juvenile / Q000150:complications* / Q000175:diagnosis / Q000601:surgery