Point-prevalence study of inappropriate antibiotic use at a tertiary Australian hospital.
A point-prevalence study at a tertiary Australian hospital found 199 of 462 inpatients (43%) to be receiving antibiotic therapy. Forty-seven per cent of antibiotic use was discordant with guidelines or microbiological results and hence considered inappropriate. Risk factors for inappropriate antibiotic prescribing included bone/joint infections, the absence of infection, creatinine level >120 µmol/L, carbapenem or macrolide use and being under the care of the aged care/rehabilitation team. In the setting of finite antimicrobial stewardship resources, identification of local determinants for inappropriate antibiotic use may enable more targeted interventions.
Department of Infectious Diseases and Microbiology, Royal Perth Hospital, Perth, WA 6000, Australia. paul.ingram@health.wa.gov.au
P R
PR
Ingram
J M
JM
Seet
C A
CA
Budgeon
R
R
Murray
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003404:Creatinine / Q000097:blood; D006801:Humans; D057970:Inappropriate Prescribing; D015999:Multivariate Analysis; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D012307:Risk Factors; D014904:Western Australia
D000900:Anti-Bacterial Agents; D003404:Creatinine