Isotherm of ligand adsorption on DNA at multiplicative noise.
Fluctuations of the number of ligands adsorbed on macromolecules are considered in the case when the number of ligands in the solution fluctuates under the action of fluctuations of the external medium (external noise). For the case of small filling, the multiplicative type of stochastic differential equation is obtained, describing the time variation of the number of ligands adsorbed on macromolecules. The isotherm of adsorption of ligands on DNA is obtained. It is shown that at small ligand concentrations, for some relations between adsorption parameters and the intensity of the external noise, no macromolecule adsorption of ligands takes place.
Department of Molecular Physics, Yerevan State University, Alek Manukyan 5, 0049, Yerevan, Armenia. v.arakelyan@ysu.am
Valeri
V
Arakelyan
Sos
S
Harutyunyan
Vardan
V
Andriasyan
Hakob
H
Arakelyan
D000327:Adsorption; D004247:DNA / Q000737:chemistry*; D008024:Ligands; D008962:Models, Theoretical
D008024:Ligands; D004247:DNA