Evaluation of clinical outcomes and bone loss around titanium implants with oxidized surface: six-year follow-up results from a prospective case series study.
OBJECTIVE
The aim of this prospective study was to assess long-term clinical outcomes and peri-implant bone level changes around oxidized implants supporting partial fixed rehabilitations.


METHODS
Twenty-two partially edentulous patients were included in the study. A total of 33 fixed rehabilitations were placed, supported by 54 titanium implants with oxidized microtextured surface. Prostheses were delivered after 3 and 6 months of implant placement in the mandible and maxilla, respectively. Patients were scheduled for follow-up at 6 and 12 months and then yearly. At each follow-up, plaque level and bleeding scores were assessed and periapical radiographs were taken. The main outcomes were prosthesis success, implant survival, implant success, and marginal bone level change.


RESULTS
Three patients were excluded from the study because they did not attend the 1-year follow-up. Nineteen patients, accounting for 49 implants, were followed for at least 6 years after prosthesis delivery. The mean follow-up duration was 81.8 months (range 75-96 months). One mandibular single-tooth implant failed after 1 year in a smoker woman. Cumulative implant survival and success at 6 years were 98.0% and 95.9%, respectively. Prosthesis success was 96.7%. The mean peri-implant bone loss at 6 years was 0.76 ± 0.47 mm. Not significantly (p = .75) greater bone loss was found in the maxilla (0.78 ± 0.14 mm, n = 19) as compared with the mandible (0.74 ± 0.59 mm, n = 30). In the maxilla, bone loss was significantly greater around implants supporting partial prostheses as compared with single-tooth implants (p = .03). Full patient satisfaction was reported.


CONCLUSIONS
Implants with oxidized microtextured surface may achieve excellent long-term clinical outcomes in the rehabilitation of partial edentulism.
Associate professor, Dental Clinic, Department of Health Technologies, IRCCS Istituto Ortopedico Galeazzi, Università degli Studi di Milano, Milano, Italy, and Center of Research in Oral Implantology, Università degli Studi di Milano, Milano, Italy Private practice, Dental Clinic, Department of Health Technologies, IRCCS Istituto Ortopedico Galeazzi, Università degli Studi di Milano, Milano, Italy Private practice, Dental Clinic, Department of Health Technologies, IRCCS Istituto Ortopedico Galeazzi, Università degli Studi di Milano, Milano, Italy Visiting professor, Dental Clinic, Department of Health Technologies, IRCCS Istituto Ortopedico Galeazzi, Università degli Studi di Milano, Milano, Italy, and Center of Research for Oral Health, Università degli Studi di Milano, Milano, Italy Academic researcher, Dental Clinic, Department of Health Technologies, IRCCS Istituto Ortopedico Galeazzi, Università degli Studi di Milano, Milano, Italy; and Center of Research in Oral Implantology, Università degli Studi di Milano, Milano, Italy; and Center of Research for Oral Health, Università degli Studi di Milano, Milano, Italy.
Luca
L
Francetti
Francesco
F
Azzola
Stefano
S
Corbella
Silvio
S
Taschieri
Massimo
M
Del Fabbro
D015921:Dental Implants; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D057893:Immediate Dental Implant Loading; D008875:Middle Aged; D010024:Osteoporosis / Q000175:diagnosis / Q000503:physiopathology*; D010084:Oxidation-Reduction; D011446:Prospective Studies; D011475:Prosthesis Failure; D013499:Surface Properties; D014025:Titanium; D016896:Treatment Outcome
D015921:Dental Implants; D014025:Titanium