Perspectives of new therapies for endometriosis.
Endometriosis is an inflammatory disease characterized by the presence of endometrial glandular epithelial and stromal cells growing in the extra-uterine environment. The disease affects: ovarian function, oocyte quality, embryo development and implantation, and uterine function resulting in infertility or spontaneous pregnancy loss. Even though the world's prevalence is above 10 %, an effective treatment has not yet been found. New pharmacological approaches have been designed and patented that could serve as future therapies for this disease.
Instituto de Inmunología, Facultad de Medicina, Universidad Central de Venezuela, Apartado 50109, Caracas 1050-A, Venezuela. jenny.garmendia@gmail.com
Jenny V
JV
Garmendia
Juan B
JB
De Sanctis
D015195:Drug Design; D055808:Drug Discovery / Q000379:methods*; D004715:Endometriosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D010330:Patents as Topic; D016387:Women's Health / Q000639:trends*