Solitary plasmacytoma of the larynx treated  with radiotherapy: a case report.
OBJECTIVE
Solitary plasmacytomas are rare tumors accounting for less than 10% of plasma cell neoplasms. On initial presentation they must be differentiated from multiple myeloma. This can be difficult because a high percentage of these tumors may be associated with subsequent development of multiple myeloma. We present a case of plasmacytoma of the larynx treated with surgery and radiotherapy.


METHODS
A 56-year-old man presented a solitary plasmacytoma of the larynx. The diagnosis was made by biopsy and the presence of a mass on the right side of the larynx was confirmed by computed tomography and whole-body positron-emission tomography. Soon after the biopsy the patient underwent a CO2 laser cordectomy. After the definitive histological confirmation, the patient was referred to our department for three-dimensional conformal radiotherapy (3DCRT) to the involved site with curative intent. The prescribed dose was 50 Gy.


RESULTS
Five months after the 3DRTE treatment there was no CT or PET evidence of tumor, and examination by the otorhinolaryngologist confirmed the success of laser cordectomy and 3DRTE treatment. There were no long-term side effects of the treatment.


CONCLUSIONS
Radiation therapy following CO2 laser cordectomy can achieve excellent locoregional control of solitary plasmacytoma of the larynx.
Department of Radiotherapy, PO Ascalesi ASLNA1, Naples, Italy. enzoravo@libero.it
Vincenzo
V
Ravo
Maria Grazia
MG
Calvanese
Roberto
R
Manzo
Maria Grazia
MG
Cuomo
Fabrizio
F
Cammarota
Paola
P
Murino
Paolo
P
Muto
D001706:Biopsy; D003937:Diagnosis, Differential; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000532:radiotherapy* / Q000601:surgery; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis; D010954:Plasmacytoma / Q000175:diagnosis / Q000532:radiotherapy* / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D020266:Radiotherapy, Conformal / Q000379:methods; D016896:Treatment Outcome; D014827:Vocal Cords / Q000601:surgery*