The prevalence of hypertension, valve calcification and left ventricular hypertrophy and geometry in peritoneal dialysis patients.
OBJECTIVE
Cardiac valve calcification (CVC) and left ventricular (LV) abnormalities are common indicators of a poor prognosis in dialysis patients. We determined the prevalence of hypertension, CVC, LV hypertrophy (LVH) and LV geometry in peritoneal dialysis (PD) patients.


METHODS
Eighty-seven patients (50 female; mean age 42 ± 13 years; mean dialysis duration 46 ± 24 months) on strict salt and volume restriction, none of whom were receiving antihypertensives, were included in the study. Blood pressure (BP), biochemical parameters, CVC, LVH and LV geometry were determined.


RESULTS
Most patients were normotensive. CVC of the mitral and aortic valves and of both valves were noted in 22, 23 and 15% of patients, respectively. Patients with CVC had significantly higher diastolic BP (p = 0.023), cardiothoracic index (CTI; p = 0.037) and LV mass index (LVMI; p = 0.002). LVH, noted overall in 44% of cases, was present in 62 and 36% of the patients with and without CVC, respectively (p = 0.028). Of the whole group, only 50.6% had normal LV geometry. LVH was associated with lower serum albumin (p = 0.002), higher CTI (p = 0.027) and more frequent CVC (p = 0.028). LVMI was greater in patients with CVC (p = 0.002).


CONCLUSIONS
Strict salt restriction and the achievement of ideal dry weight result in normotension in PD patients. CVC is associated with LVH, both of which are lower in normotensive patients.
Nephrology Department, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey. murvetyilmaz @ hotmail.com
Murvet
M
Yilmaz
Abdulkadir
A
Unsal
Erkan
E
Oztekin
Ozgu
O
Kesmezacar
Ozlem Harmankaya
OH
Kaptanogullari
Nezaket
N
Eren
D000328:Adult; D001021:Aortic Valve / Q000473:pathology; D001024:Aortic Valve Stenosis / Q000175:diagnosis / Q000453:epidemiology*; D002114:Calcinosis / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology*; D017379:Hypertrophy, Left Ventricular / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000473:pathology; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D015995:Prevalence