Metal-free, organocatalytic syn diacetoxylation of alkenes.
A novel method for the organocatalytic syn diacetoxylation of alkenes has been developed using aryl iodides as efficient catalysts. A broad range of substrates, including electron-rich as well as electron-deficient alkenes, are smoothly transformed by the new procedure, furnishing the desired products in good to excellent yields with high diastereoselectivity (up to >19:1 dr).
The State Key Laboratory of Natural and Biomimetic Drugs, Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Beijing 100191, P.R. China.
Wenhe
W
Zhong
Shan
S
Liu
Jun
J
Yang
Xiangbao
X
Meng
Zhongjun
Z
Li
D000107:Acetylation; D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D004952:Esters / Q000138:chemical synthesis* / Q000737:chemistry; D006847:Hydrocarbons, Iodinated / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
D000475:Alkenes; D004952:Esters; D006847:Hydrocarbons, Iodinated