Factor X deficiency: a rare cause of puberty menorrhagia.
Factor X deficiency is an extremely rare coagulation defect inherited as an autosomal recessive disorder with variable bleeding manifestations. The authors report case of a 16 y-old girl born from a consanguineous marriage who presented with excessive bleeding at the start of menarche. Investigations revealed severe anemia, prolongation of both prothrombin time and activated partial thromboplastin time and moderate deficiency of factor X (1 %). She was given multiple transfusions including packed cells and fresh frozen plasma and was advised to remain under regular follow up.
Department of Pediatrics, SMGS Hospital, Shalamar, Jammu, India. virta266@yahoo.in
Virender
V
Singh
Tania
T
Kakkar
Sanjeev K
SK
Digra
Manisha
M
Kakkar
D000293:Adolescent; D001803:Blood Transfusion; D003241:Consanguinity; D005171:Factor X Deficiency / Q000175:diagnosis* / Q000628:therapy*; D005260:Female; D006801:Humans; D008572:Menarche; D008595:Menorrhagia / Q000209:etiology