Ovarian metastasis in a transposed ovary 10 years after primary cervical cancer: the importance of histologic examination and review of literature.
Cases of cervical carcinoma metastasing to the transposed ovary are rarely reported in the literature. In this report, the authors present the case of a 53-year-old woman with a persisting, unsuspected cyst in the right transposed ovary, 10 years after treatment for adenosquamous carcinoma of the cervix. It is the first report describing a secondary ovarian malignancy originating from a cervical adenosquamous carcinoma in a transposed ovary. In addition, this is the first account of an ovarian metastasis 10 years after primary treatment for cervical cancer. Furthermore, pathologic examination with immunohistochemistry and human papillomavirus genotyping played a key role in the diagnostic process, as the case did not raise suspicion by ultrasound findings neither by cytological examination after cytological aspiration or by appearance during surgery.
Division of Woman and Baby, Department of Gynaecologic Oncology, University Medical Centre, Utrecht, The Netherlands.
Julienne A
JA
Janse
Daisy M D S
DM
Sie-Go
Henk W R
HW
Schreuder
D018196:Carcinoma, Adenosquamous / Q000556:secondary*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000556:secondary*; D010053:Ovary / Q000473:pathology*; D013997:Time Factors; D002583:Uterine Cervical Neoplasms / Q000473:pathology*