Progressive seizures in a patient with congenital coagulopathies.
Dural arteriovenous fistula (DAVF) is a rare complication of cerebral venous sinus thrombosis (CVST). DAVFs develop as a result of direct arterial to venous sinus communications evolving in response to an occluded sinus. The authors present a patient with Down's syndrome who developed progressive, uncontrolled seizures and chronic CVST secondary to factor V Leiden deficiency. Brain MRI and computerised tomographic venography revealed a complex secondary DAVF, which once embolised resulted in a dramatic reduction in seizures and improvement in the clinical state. DAVFs should be considered as a potential complication in patients with persistent features of CVST.
Acute Stroke Unit, Torbay Hospital, Devon, UK.
Rosanna
R
Berryman
Ibrahim
I
Imam
Peter C
PC
Whitfield
William
W
Mukonoweshuro
Isam
I
Salih
D001778:Blood Coagulation Disorders / Q000150:complications* / Q000151:congenital*; D018450:Disease Progression; D005260:Female; D006801:Humans; D008875:Middle Aged; D012640:Seizures / Q000209:etiology*