The dysplastic nevus: from historical perspective to management in the modern era: part I. Historical, histologic, and clinical aspects.
Since its description in the 1970s, the dysplastic nevus has been a source of confusion, and whether it represents a precursor to melanoma remains a controversial subject. Although a Consensus Conference in 1992 recommended that the term "dysplastic nevus" no longer be used, the histologic diagnosis continues to present a therapeutic quandary for dermatologists and other physicians, and there remains significant variation in clinical management. In part I of this continuing medical education review, we will discuss the historical origins of the term, the evidence for its distinct histologic basis, and its clinical significance.
Department of Dermatology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA.
Keith
K
Duffy
Douglas
D
Grossman
D004416:Dysplastic Nevus Syndrome / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D006801:Humans; D008545:Melanoma / Q000235:genetics; D012307:Risk Factors; D012878:Skin Neoplasms / Q000235:genetics; D009626:Terminology as Topic