[Stages of bone regeneration and foundation of pharmacоlogical correction of the mandible reparative osteogenesis].
Influents of some medicines on the mandible reparative regeneration in experimental investigations are present in the manuscript. It was discovered that application of parathyroid hormone (PTG) in first 3 days after the mandible fracture decreases of quantity complications on 30% and contributes strong consolidation of bone fragments. Metiluracil in the same period increases complications quantity on 36% and bone fragments consolidation strength was for sure less than after PTG. It was found PTG and vitamin D3 in first resorbtion stage accelerate bone consolidation, retabolil (nandrolone), dexametasone, testosterone and vitamin E slow down bone consolidation. Role of vitamin A, indometazin and calcitonin was doubtful. Practical doctors and experimenters co-ordination efforts are necessary for elaboration of new tactic and strategy of patient treatment with bone trauma.
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Shvyrkov
D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects* / Q000502:physiology*; D002116:Calcitonin / Q000008:administration & dosage; D003907:Dexamethasone / Q000008:administration & dosage; D007213:Indomethacin / Q000008:administration & dosage; D008334:Mandible / Q000187:drug effects* / Q000502:physiology*; D008338:Mandibular Injuries / Q000150:complications / Q000188:drug therapy*; D009277:Nandrolone / Q000008:administration & dosage / Q000031:analogs & derivatives; D000077603:Nandrolone Decanoate; D010012:Osteogenesis / Q000187:drug effects*; D010281:Parathyroid Hormone / Q000008:administration & dosage; D051381:Rats; D013739:Testosterone / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage / Q000031:analogs & derivatives; D014801:Vitamin A / Q000008:administration & dosage; D014810:Vitamin E / Q000008:administration & dosage
D010281:Parathyroid Hormone; D014801:Vitamin A; D014810:Vitamin E; D013739:Testosterone; D014498:Uracil; C008378:6-methyluracil; D009277:Nandrolone; D003907:Dexamethasone; D002116:Calcitonin; D000077603:Nandrolone Decanoate; D007213:Indomethacin