Recombinant activated factor VII as treatment for uncontrolled mucosal haemorrhage.
We report the use of a haemostatic drug (recombinant activated factor VII (rFVIIa)) in a patient who presented a slow but constant bleed in oesophageal mucosa (which required frequent red blood cell transfusion) due to ingestion of caustic products. The administration of rFVIIa ceased bleeding and allowed mucosal cicatrisation and patient haemodynamic stabilisation and clinical recovery.
Department of ICU, Ramon y Cajal Hospital, Madrid, Spain. jan.grazia@gmail.com
J
J
Gracia
I
I
Prieto
D000328:Adult; D004935:Esophageal Diseases / Q000188:drug therapy*; D015942:Factor VIIa / Q000627:therapeutic use*; D006470:Hemorrhage / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009092:Mucous Membrane; D011994:Recombinant Proteins / Q000627:therapeutic use
D011994:Recombinant Proteins; C103587:recombinant FVIIa; D015942:Factor VIIa