Diagnostic and therapeutic challenges in a liver transplant recipient with central nervous system invasive aspergillosis.
This is a case report of central nervous system (CNS) invasive aspergillosis (IA) in a liver transplant recipient, which illustrates the utility of enzyme-based diagnostic tools for the timely and accurate diagnosis of IA, the treatment challenges and poor outcomes associated with CNS IA in liver transplant recipients.
Division of Infectious Disease, The Johns Hopkins University, School of Medicine, Baltimore, MD 21205, USA. dneofyt1@jhmi.edu
Dionissios
D
Neofytos
Shmuel
S
Shoham
Kerry
K
Dierberg
Katharine
K
Le
Simon
S
Dufresne
Sean X
SX
Zhang
Kieren A
KA
Marr
D000293:Adolescent; D000935:Antifungal Agents / Q000008:administration & dosage; D006801:Humans; D016867:Immunocompromised Host; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008828:Microbiological Techniques / Q000379:methods; D009172:Mycology / Q000379:methods; D020953:Neuroaspergillosis / Q000175:diagnosis* / Q000188:drug therapy*; D014180:Transplantation; D016896:Treatment Outcome
D000935:Antifungal Agents