[Chemical components in Hemsleya chensnsis (III)].
OBJECTIVE
To study the chemical constituents of Hemsleya chensnsis.


METHODS
Various chromatographic techniques were used to separate and purify the constituents. The spectral data (MS, NMR) were obtained for structure elucidation.


RESULTS
Eight known triterpenoid saponins were isolated from the root of H. chensnsis. Their structures were elucidated as dihydrocucurbitacin B (1), 25-O-acetyl-dihydrocucurbitacin F (2), cucurbitacin F (3), 3-O-(6'-ethyl ester) -beta-D-glucuropyranosyl oleanolic acid-28-O-alpha-L-arabinopyranoside (4), oleanolic acid-3-(6'-methyl ester) -beta-D-glucuropyranosyl (1-3) -alpha-L-arabinopyranoside (5), oleanolic acid-28-O-beta-D-glucopyranosyl-(1-6) -beta-D-glucopyranoside (6), 3-O-(6'-methyl ester) -beta-D-glucuropyranosyl oleanolic acid-28-O-beta-D-glucopyranosyl-(1-6) -beta-D-glucopyranoside (7), 3-O-(6'-methyl ester) -beta-D-glucuropyranosyl (1-2) -beta-D-glucopyranoside-oleanolic acid-28-O-beta-D-glucopyranoside (8).


CONCLUSIONS
All compounds except for 2 were isolated from H. chensnsis for the first time.
Department of Pharmacology, Wenzhou Medical College, Wenzhou 325035, China. jianyd163@163.com
Jianyong
J
Dong
Lei
L
Yue
Weiwei
W
Shao
Jinzhong
J
Xu
D019662:Cucurbitaceae / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008516:Medicine, Chinese Traditional; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification
D012503:Saponins; D014315:Triterpenes