Comprehensive analysis of flavonols in Ginkgo biloba products by ultra-high-performance liquid chromatography coupled with ultra-violet detection and time-of-flight mass spectrometry.
The aim of this study was to survey the flavonol compositions of Ginkgo biloba products, especially those on the Japanese market. Sixteen food products, six medicinal products, and raw Ginkgo biloba leaves were examined by ultra-high-performance liquid chromatography coupled with ultra-violet detection and time-of-flight mass spectrometry. Eleven flavonol glycosides, three biflavones, and a flavonol aglycone were qualified by analysis of accurate mass spectra. The quantitative data obtained were then applied to multivariate data analysis, and the flavonol compositions of the food and medicinal products were classified into four groups. Most of the food products were classified into the same group as the medicinal products, which contained high percentages of flavonol glycosides. On the other hand, some food products contained high percentages of biflavones or an aglycone.
Research Laboratories for Food Safety Chemistry, Asahi Group Holdings, Ltd., Moriya, Ibaraki, Japan.
Yasuhiro
Y
Kakigi
Takashi
T
Hakamatsuka
Takeshi
T
Icho
Yukihiro
Y
Goda
Naoki
N
Mochizuki
D002851:Chromatography, High Pressure Liquid; D044948:Flavonols / Q000032:analysis*; D020441:Ginkgo biloba / Q000737:chemistry*; D006027:Glycosides / Q000032:analysis*; D006801:Humans; D007564:Japan; D056951:Photoelectron Spectroscopy; D018515:Plant Leaves / Q000737:chemistry*; D025341:Principal Component Analysis; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
D044948:Flavonols; D006027:Glycosides