Concurrent onset of an eosinophilic ulcer of the oral mucosa with peripheral eosinophilia in a human T-cell leukemia virus type I carrier.
We present a case of a 46-year-old Japanese woman with an eosinophilic ulcer of the oral mucosa (EUOM), located in the buccal mucosa, who was found by various examinations to be a human T-cell leukemia virus type I (HTLV-1) carrier with peripheral eosinophilia. Her peripheral eosinophilia and EUOM promptly improved in response to oral corticosteroid therapy. EUOM has been described to be possibly associated with trauma, but its etiology has not been fully elucidated to date. In the present case, the presence of peripheral eosinophilia in addition to the EUOM indicated possible influence of certain immune system abnormalities associated with HTLV-1 infection.
Department of Oral Surgery, Tokai University School of Medicine, Isehara, Kanagawa, Japan. osyamaza@is.icc.u-tokai.ac.jp
Hiroshi
H
Yamazaki
Yukari
Y
Shirasugi
Hiroshi
H
Kajiwara
Masashi
M
Sasaki
Mitsunobu
M
Otsuru
Takayuki
T
Aoki
Yoshihide
Y
Ota
Akihiro
A
Kaneko
Naoya
N
Nakamura
D002353:Carrier State; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D005260:Female; D015368:Human T-lymphotropic virus 1 / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D019226:Oral Ulcer / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D011862:Radiography, Panoramic; D014057:Tomography, X-Ray Computed; D014081:Tooth Extraction