[Nanostructured liposomal systems as transport agents for anticancer drugs].
Liposomes quite recently have turned from a model of biological membranes into an object of extensive research and practical use. The versatile traits of liposomal formulation allow its' universal implementation, especially in cancer chemotherapy. The advantages of liposomal use as a carrier of an anticancer drug for its targeted selective accumulation are discussed in this article. This article contains description of new types of liposomes, differing in contents and use, such as: simple, sterically stabilized, targeted (immunoliposomes),cationic, sensitive to physical and chemical stimuli. The characteristics of liposomal systems of anticancer drug delivery designed at Blokhin Russian Oncological Scientific Centre is given in the article.
A Iu
AIu
Baryshnikov
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002412:Cations; D004337:Drug Carriers; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D008081:Liposomes / Q000008:administration & dosage* / Q000737:chemistry* / Q000276:immunology; D008833:Microcirculation; D049329:Nanostructures; D009369:Neoplasms / Q000098:blood supply
D000970:Antineoplastic Agents; D002412:Cations; D004337:Drug Carriers; D008081:Liposomes