Cytotoxic T lymphocytes: Sniping cancer stem cells.
Cancer stem cells (CSCs)/cancer-initiating cells (CICs) are characterized as a small population of cancer cells that have high tumor-initiating ability. CSCs/CICs are resistant to several cancer therapies, and eradication of CSCs/CICs is essential to cure cancer. How can we eradicate CSCs/CICs? Cytotoxic T lymphocytes (CTLs) might be a promising answer.
Department of Pathology; Sapporo Medical University School of Medicine; Sapporo, Japan.
Yoshihiko
Y
Hirohashi
Toshihiko
T
Torigoe
Satoko
S
Inoda
Rena
R
Morita
Vitaly
V
Kochin
Noriyuki
N
Sato