Carbamazepine-induced agammagloblinaemia clinically mimicking diffuse panbronchiolitis.
The authors report the case of a 61-year-old man who presented with carbamazepine (CBZ)-related agammagloblinaemia accompanied by sinobronchial syndrome clinically mimicking diffuse panbronchiolitis (DPB). The patient's laboratory and radiographic findings improved significantly after cessation of CBZ, and administration of gammaglobulin and long-term oral macrolides therapy. In patients on long-term CBZ treatment, the physician should be aware of the possible development of secondary immunodeficiency, which can cause small airway diseases sharing common clinical features with DPB.
Department of General Internal Medicine, Ohta-Nishinouchi Hospital, Koriyama City, Japan. gim-hoshino@ohta-hp.or.jp
Chisho
C
Hoshino
Tadashige
T
Hoshi
D000361:Agammaglobulinemia / Q000139:chemically induced* / Q000175:diagnosis*; D001988:Bronchiolitis / Q000175:diagnosis*; D002220:Carbamazepine / Q000009:adverse effects*; D003937:Diagnosis, Differential; D006192:Haemophilus Infections / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged
D002220:Carbamazepine