Color Doppler imaging of eyes with persistent fetal vasculature.
BACKGROUND
Eyes with persistent fetal vasculature (PFV) may be mistaken for retinoblastoma and provide a diagnostic challenge.


OBJECTIVE
This study aimed to evaluate the role of color Doppler imaging (CDI) in children with persistent fetal vasculature.


METHODS
Eyes with a diagnosis of PFV were evaluated by CDI.


RESULTS
Twenty eyes of 17 children were included. All had a confirmed diagnosis of PFV based on one or more of the following: clinical findings on funduscopy, characteristic findings on imaging modalities (ophthalmic gray-scale US, CT and/or MRI), typical findings observed intraoperatively, and histopathological analysis (after enucleation in one case). Blood flow within the PFV was demonstrated in 19 eyes in this series.


CONCLUSIONS
CDI is a noninvasive diagnostic tool that may add useful information on the presence of blood flow within the PFV and may substantiate the diagnosis of PFV in cases of uncertainty.
Department of Ophthalmology, Tel Aviv medical center, 6 Weizmann Street, Tel Aviv, 64239, Israel. meiraneu@netvision.net.il
Meira
M
Neudorfer
Michael
M
Waisbourd
Sharon
S
Buzi
Tamara
T
Wygnanski-Jaffe
Chaim
C
Stolovitch
Adiel
A
Barak
Dafna
D
Goldenberg
Ada
A
Kessler
D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D054514:Persistent Hyperplastic Primary Vitreous / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D019572:Retinal Neoplasms / Q000000981:diagnostic imaging; D012175:Retinoblastoma / Q000000981:diagnostic imaging; D012680:Sensitivity and Specificity; D018615:Ultrasonography, Doppler, Color / Q000379:methods*