Hemophagocytic syndrome complicating lung resection.
A 68-year-old man underwent a left upper lobectomy for squamous cell lung carcinoma. After 15 days, he was readmitted with fever, dyspnea, and a skin rash. Computed tomography showed a pleural effusion, which was drained. He was diagnosed with hemophagocytic syndrome in view of the fever, skin rash, bicytopenia, hypertriglyceridemia, high lactate dehydrogenase, and raised ferritin levels. His clinical condition deteriorated in spite of steroid therapy, and he died on the 23rd postoperative day.
Division of Thoracic Surgery, Department of Surgical Oncology, Tata Memorial Hospital, India.
Sabita
S
Jiwnani
George
G
Karimundackal
Atul
A
Kulkarni
C S
CS
Pramesh
D000368:Aged; D001706:Biopsy; D001856:Bone Marrow Examination; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000601:surgery*; D051359:Lymphohistiocytosis, Hemophagocytic / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D011013:Pneumonectomy / Q000009:adverse effects*; D013256:Steroids; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D017211:Treatment Failure
D013256:Steroids