Sulfur Hexafluoride 20% versus Lactated Ringer's Solution for Prevention of Early Postoperative Vitreous Hemorrhage after Diabetic Vitrectomy.
OBJECTIVE
To compare the hemostatic effect of sulfur hexafluoride 20% (SF6 20%) with lactated Ringer's solution for prevention of early postoperative vitreous hemorrhage following diabetic vitrectomy.


METHODS
In a prospective randomized clinical trial, 50 eyes undergoing diabetic vitrectomy were divided into two groups. At the conclusion of surgery, in one group the vitreous cavity was filled with SF6 20% while in the other group lactated Ringer's solution was retained in the vitreous cavity. The two groups were compared for the rate of early postoperative vitreous hemorrhage.


RESULTS
The incidence of vitreous hemorrhage was lower in the SF6 group than the Ringer's group 4 days (20% vs 68%, P=0.001), 7 days (24% vs 60%, P=0.01) and 4 weeks (16% vs 40%, P=0.059) after vitrectomy.


CONCLUSIONS
In comparison with lactated Ringer's solution, SF6 20% had a significant hemostatic effect especially in the early postoperative period after diabetic vitrectomy and reduced the incidence of vitreous hemorrhage.
Department of Ophthalmology, Jundishapur University of Medical Sciences, Ahvaz, Iran.
Fereydoun
F
Farrahi
Mostafa
M
Feghhi
Biuk
B
Bagherzadeh
Mahmood
M
Latifi