Computational identification of sRNA targets.
Many small noncoding RNAs (sRNAs) in bacteria act as posttranscriptional regulators by base pairing to their message targets. TargetRNA is a program that predicts the targets of a sRNA by identifying messages with significant potential to base pair with the sRNA. Since base pairing potential alone is insufficient to accurately identify sRNA targets, TargetRNA integrates several additional features of RNA interactions when predicting regulatory targets of a sRNA. In this chapter, we provide a detailed guide on how to use TargetRNA to identify targets of sRNA regulation.
Computer Science Department, Wellesley College, Wellesley, MA, USA. btjaden@wellesley.edu
Brian
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Tjaden
D019295:Computational Biology / Q000379:methods*; D058727:RNA, Small Untranslated / Q000235:genetics / Q000378:metabolism*; D012984:Software
D058727:RNA, Small Untranslated