One-day behavioral treatment for patients with comorbid depression and migraine: a pilot study.
BACKGROUND
Migraine is a common and disabling disorder that is highly comorbid with depression. The comorbidity of depression and migraine is a major health concern as it results in poorer prognosis and quality of life. Yet, effective treatments have rarely been investigated.


METHODS
45 patients with comorbid migraine and depression were assigned to a 1-day Acceptance and Commitment Training plus Migraine Education workshop (ACT-ED; N = 31) or to Wait List/Treatment as Usual (WL/TAU; N = 14). Assessment of depressive symptoms, general functioning, and migraine related disability were completed at baseline and 2-, 6-, and 12 weeks after the workshop.


RESULTS
At the 3-month follow up, participants in the ACT-ED condition exhibited significantly greater improvements in depressive symptoms, general functioning, and migraine-related disability than patients in the WL/TAU group.


CONCLUSIONS
A 1-day ACT-ED workshop is a promising approach to the treatment for depression and disability in migraineurs that merits further investigation.
University of Iowa College of Medicine, Department of Psychiatry, Iowa City, IA 52242, USA. lilian-dindo@uiowa.edu
Lilian
L
Dindo
Ana
A
Recober
James N
JN
Marchman
Carolyn
C
Turvey
Michael W
MW
O'Hara
D000293:Adolescent; D000328:Adult; D000368:Aged; D000928:Antidepressive Agents / Q000627:therapeutic use; D001521:Behavior Therapy / Q000379:methods*; D003865:Major Depressive Disorder / Q000150:complications / Q000628:therapy*; D006233:Persons with Disabilities; D005240:Feasibility Studies; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000150:complications / Q000628:therapy*; D010353:Patient Education as Topic; D010865:Pilot Projects; D016896:Treatment Outcome; D055815:Young Adult
D000928:Antidepressive Agents