Correlation of extracranial internal carotid artery tortuosity index and intraprocedural complications during carotid artery stenting.
BACKGROUND
To investigate the correlation between tortuosity of extracranial internal carotid artery (EICA) and intraprocedural complications in patients undergoing carotid artery stenting (CAS).


METHODS
The study included 244 EICA in 223 patients undergoing CAS. Tortuosity in EICA was measured by the tortuosity index (TI). Multivariate logistic regression was performed to assess the independent risk factors of vasospasm during CAS. Receiver operating characteristic curve was performed to identify the cut-off of TI to predict vasospasm.


RESULTS
During the 244 CAS, 71 EICA presented vasospasm and 114 CAS presented hypotension. High TI, long procedural duration and female are independent risk factors for vasospasm during CAS. TI of 118 was the optimal cut-off to predict vasospasm during CAS (sensitivity: 85.9%, specificity: 78.6%). Linear regression analysis demonstrated that TI is positively correlated with procedural duration (p < 0.001). There was no significant difference in TI between the hypotension and non-hypotension groups (p = 0.145).


CONCLUSIONS
TI is an independent risk factor for vasospasm during CAS and a TI ≥118 has the high sensitivity and specificity to predict vasospasm. Our results indicate the value of assessing tortuosity of EICA prior to choosing or performing the procedure in patients with carotid stenosis or occlusion.
Department of Neurology, Jinling Hospital, Southern Medical University, Nanjing, China.
Qizhang
Q
Wang
Chaolai
C
Liu
Bernard
B
Yan
Xiaobin
X
Fan
Min
M
Zhang
Yongkun
Y
Li
Wusheng
W
Zhu
Maogang
M
Chen
Xianjun
X
Huang
Zhizhong
Z
Zhang
Gelin
G
Xu
Xinfeng
X
Liu
D000368:Aged; D000792:Angiography; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000601:surgery*; D016893:Carotid Stenosis / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007022:Hypotension / Q000453:epidemiology*; D007431:Intraoperative Complications / Q000453:epidemiology*; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D061646:Operative Time; D012372:ROC Curve; D012680:Sensitivity and Specificity; D013035:Spasm / Q000453:epidemiology*; D015607:Stents