A case of warfarin-induced eosinophilia.
Warfarin is widely used in clinical practice all over the world. We report a man in whom prominent eosinophilia appeared after the initiation of warfarin administration following aortic valve replacement. Laboratory data following the administration and discontinuation of warfarin suggested that this drug was responsible for the eosinophilia. It is important to recognize the possibility of warfarin-induced hypereosinophilia as a latent adverse effect even when there are no clinical signs or symptoms.
Division of Cardiology, Department of Internal Medicine, Ohno Memorial Hospital, Japan. teragaki@med.osaka-cu.ac.jp
Masakazu
M
Teragaki
Hitomi
H
Kawano
Ryojiro
R
Makino
Keisuke
K
Inoue
Yoshinori
Y
Sai
Mitsuharu
M
Hosono
Shigefumi
S
Suehiro
Mikio
M
Okamura
D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects; D001021:Aortic Valve; D001705:Bioprosthesis; D004802:Eosinophilia / Q000097:blood / Q000139:chemically induced*; D006350:Heart Valve Prosthesis; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D014859:Warfarin / Q000009:adverse effects*
D000925:Anticoagulants; D014859:Warfarin