[A case of advanced gastric cancer with multiple liver metastases that achieved long-term survival on monotherapy of S-1].
A 74-year-old woman was referred to us for patterns of liver metastases found in abdominal ultrasonography. Upper gastrointestinal endoscopy revealed advanced gastric cancer, and the subsequent abdominal CT examination confirmed multiple liver metastases. After the first regimen, a combination of 5-FU and CDDP failed due to adverse events, so monotherapy of S-1 was introduced. An abdominal CT examination in the 21st month showed disappearance of liver metastases. She was judged to have a complete response and continued with this treatment. She survived five years and eight months on monotherapy of S-1 before she died of bronchiectasis.
Dept. of Gastroenterology, Tsuchiura Kyodo General Hospital.
Toshiki
T
Masuishi
Yoshinori
Y
Sakai
Tomoko
T
Soma
Kazunori
K
Nagayama
Fumihiko
F
Kusano
Junichi
J
Tazawa
D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001987:Bronchiectasis / Q000150:complications; D004338:Drug Combinations; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D010094:Oxonic Acid / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D005641:Tegafur / Q000627:therapeutic use*; D014057:Tomography, X-Ray Computed
D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid