Direct and indirect exposure to horse: risk for sensitization and asthma.
Most studies on the sensitization to horse allergens in populations without professional exposure have been carried out in geographical areas where the rate of horse ownership is high and horse riding is popular. Very few studies have been carried out in populations living in large urban areas. This gap in the literature probably reflects the widespread view that prevalence of horse-related allergy is low in urban populations because the latter are not regularly exposed to horses. On the contrary, we suggest that urban areas constitute a model useful to study potential modalities of exposure and sensitization to horse allergen by other routes of exposure than horse-riding. In this article, we describe the risks related to various modalities of exposure to horse allergen, clinical aspects of airway sensitization to horse allergens in patients living in urban areas, and non-occupational exposure to horse allergen. In addition, we illuminate some aspects related to dispersion of horse allergens from sources such as stables to indoor environments.
Department of Chest Diseases, Division of Pneumology and Allergology, High Speciality A. Cardarelli Hospital, Piazzetta Arenella n° 7, 80128, Naples, Italy. gennaro.liccardi@tin.it
Gennaro
G
Liccardi
Gunnel
G
Emenius
Anne-Sophie
AS
Merritt
Antonello
A
Salzillo
Maria
M
D'Amato
Gennaro
G
D'Amato
D000485:Allergens / Q000009:adverse effects* / Q000276:immunology; D000818:Animals; D001249:Asthma / Q000209:etiology* / Q000276:immunology; D004781:Environmental Exposure / Q000009:adverse effects*; D006736:Horses / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology; D007114:Immunization / Q000009:adverse effects*; D054834:Lipocalins / Q000009:adverse effects / Q000276:immunology; D012306:Risk; D014505:Urban Population
D000485:Allergens; D054834:Lipocalins