Psychosis in a cocaine-dependent patient with ADHD during treatment with methylphenidate.
OBJECTIVE
The objective was to report a case of experienced psychosis during the treatment with methylphenidate (MPH) in a cocaine-dependent adult treated for attention-deficit/hyperactivity disorder (ADHD) with comorbid cocaine dependence.


CONCLUSIONS
ADHD is a frequent comorbidity in substance use disorder (SUD) patients. MPH may be effective in treating ADHD symptoms in SUD patients, thus preventing possible adverse outcomes. Cocaine-induced psychosis may be a risk factor for development of psychosis in the presence of a concurrent treatment with MPH.
Department of Psychiatry, Universidade Federal de Minas Gerais, Brazil.
Héloïse
H
Delavenne
Frederico
F
Duarte Garcia
Jérôme
J
Lacoste
Samuele
S
Cortese
Aimé
A
Charles-Nicolas
Nicolas
N
Ballon
D000328:Adult; D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy* / Q000523:psychology; D000697:Central Nervous System Stimulants / Q000009:adverse effects*; D019970:Cocaine-Related Disorders / Q000523:psychology*; D006801:Humans; D008297:Male; D008774:Methylphenidate / Q000009:adverse effects*; D011605:Psychoses, Substance-Induced / Q000209:etiology*
D000697:Central Nervous System Stimulants; D008774:Methylphenidate