[Observation on therapy efficacy of external auditory canal eczema by treatment of compound betamethasone and benzathine penicillin].
OBJECTIVE
To observe therapy efficacy of external auditory canal eczema by deeply injecting compound betamethasone and benzathine penicillin into patients muscles.


METHODS
Sixty patients were randomly divided into two groups. In the treatment group 30 patients were deeply injected compound betamethasone injection 1 ml and benzathine penicillin 1 200 000 U into muscles on their hips both sides one times. In the control group 30 patients were given desloratadine 5 mg orally one times a day and amoxicillin capsules 0.5 mg orally three times a day, both kinds of medicine were continuously taken for one week. No other medication was used during the treatment of two groups, keeping skin clean and dry, and judge therapy efficacy after one week.


RESULTS
The cure rate was 60.00% and the total efficiency was 96.67% in the treatment group; the cure rate was 26.67% and the total efficiency was 73.33% in the control group. Compare with cure rate of two groups, chi2 = 6.67, P < 0.01, in which there was significant difference. Compare with total efficiency of two groups, chi2 = 4.71, P < 0.05, in which there was also significant difference. The therapy effect started in two hours quickly and in three days slowly in the treatment group, an average of 0.5 days. The therapy effect started in two days quickly and in five days slowly in the control group, an average of 2.5 days.


CONCLUSIONS
The method of the treatment group is simple, quick, effective and without adverse reaction.
Department of Otorhinolaryngology, Yangtze shipping General Hospital, Wuhan Brain Hospital, Wuhan 430000, China. zlhzmm@21cn.com
Heping
H
Yang
Donghui
D
Liang
D000293:Adolescent; D000328:Adult; D001623:Betamethasone / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004424:Ear Canal / Q000473:pathology*; D004485:Eczema / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D010401:Penicillin G Benzathine / Q000627:therapeutic use*; D055815:Young Adult
D001623:Betamethasone; D010401:Penicillin G Benzathine