Prevalence of class 1 integron among multidrug-resistant Acinetobacter baumannii in Tabriz, northwest of Iran.
Integrons are associated with a variety of gene cassettes, which confer resistance to multiple classes of antibacterial drugs. In this study we tested the frequency of class 1 and 2 integrons among multidrug-resistant Acinetobacter baumannii (MDRAB) clinical isolates. One hundred clinical isolates of A. baumannii were screened for carriage of class 1 and 2 integrons by PCR method. Results showed that seventy four (92.5%) of 80 MDRAB carried class 1 integron. Integron-positive isolates were statistically more resistant to aminoglycoside, quinolone and beta-lactam compounds except for cefepime. This is the first report of class 1 integrons in MDRAB isolates in northwest Iran.
Department of Microbiology, Faculty of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran.
Amir
A
Peymani
Safar
S
Farajnia
Mohammad Reza
MR
Nahaei
Nasrollah
N
Sohrabi
Laleh
L
Abbasi
Khalil
K
Ansarin
Fatemeh
F
Azhari
D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006801:Humans; D032023:Integrons; D008297:Male; D008875:Middle Aged