[Characteristics of the immune system parameters in residents of the Far Eastern region during physiological aging].
We studied the basic indicators of immune status of healthy persons of different age groups living in the monsoon climate in the southern Far East. The analysis shows age-dependent development of immunodepressive status, combined with increasing levels of CD16, CD25 and HLA-DR in the aging organism. Climatic and anthropogenic factors effect profoundly damaging on the body, which results in the severity of disorders of the immune system in old, old age and longevity.
T A
TA
Gvozdenko
O Iu
OIu
Kytikova
T I
TI
Vitkina
P V
PV
Borshchev
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000097:blood / Q000276:immunology* / Q000502:physiology; D003627:Data Interpretation, Statistical; D005260:Female; D058851:GPI-Linked Proteins / Q000276:immunology; D006684:HLA-DR Antigens / Q000276:immunology; D006801:Humans; D007107:Immune System / Q000502:physiology*; D007136:Immunoglobulins / Q000097:blood; D053645:Interleukin-2 Receptor alpha Subunit / Q000276:immunology; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D017452:Receptors, IgG / Q000276:immunology; D012426:Russia; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology; D055815:Young Adult
C428200:FCGR3B protein, human; D058851:GPI-Linked Proteins; D006684:HLA-DR Antigens; C508017:IL2RA protein, human; D007136:Immunoglobulins; D053645:Interleukin-2 Receptor alpha Subunit; D017452:Receptors, IgG