Structure-based tuning of T(m) in lipid-like ionic liquids. Insights from Tf2N- salts of gene transfection agents.
Ionic liquids of cations bearing two lipid-like aliphatic tails are shown to have values of T(m) that can be very low, and that can be tuned up or down by the addition, deletion, or combination of dipolar modules and side-chain double bonds.
Department of Chemistry, The University of South Alabama, Mobile, Alabama 36688, USA.
Arsalan
A
Mirjafari
Samuel M
SM
Murray
Richard A
RA
O'Brien
Alexandra C
AC
Stenson
Kevin N
KN
West
James H
JH
Davis
D002152:Calorimetry, Differential Scanning; D007093:Imidazoles / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D008055:Lipids / Q000737:chemistry*; D012492:Salts / Q000737:chemistry*; D013449:Sulfonamides / Q000737:chemistry*; D014162:Transfection; D044366:Transition Temperature
D007093:Imidazoles; D052578:Ionic Liquids; D008055:Lipids; D012492:Salts; D013449:Sulfonamides; C545574:bis(trifluoromethanesulfonyl)amide