A review of nonsurgical treatment for the symptom of irritability in infants with GERD.
OBJECTIVE
The purpose of this review was to assess effectiveness of nonsurgical treatment on irritable behavior of infants with gastroesophageal reflux disease.


METHODS
A systematic literature review was conducted.


RESULTS
Research targeted treatment for irritability in infants with gastroesophageal reflux disease. All interventions including placebo were similar in reducing irritability. Which specific intervention is best for which infant is not yet known. Minor adverse effects that could increase discomfort in infants were found with pharmacologic treatments.


CONCLUSIONS
Knowledge of the effects of treatment on irritability and regurgitation can assist the nurse to work with other care providers in deciding how best to treat an individual infant.
University of Colorado College of Nursing, Aurora, Colorado, USA. Madalynn.Neu@UCdenver.edu
Madalynn
M
Neu
Elizabeth
E
Corwin
Suzanne C
SC
Lareau
Cassandra
C
Marcheggiani-Howard
D000342:Affective Symptoms / Q000150:complications / Q000175:diagnosis / Q000451:nursing* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D005764:Gastroesophageal Reflux / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000451:nursing*; D006801:Humans; D007223:Infant; D007508:Irritable Mood; D008297:Male; D010371:Pediatric Nursing / Q000379:methods; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D012307:Risk Factors; D012720:Severity of Illness Index; D016896:Treatment Outcome
D054328:Proton Pump Inhibitors