[Qualitative and quantitative assessment on the HPLC fingerprint of BYHW decoction extract by total quantum statistical moment].
OBJECTIVE
To analyse the HPLC fingerprint of BYHW decoction extract.


METHODS
HPLC fingerprint of ten BYHW decoction extracts were established to calculate correlation parameter by total quantum statistcol moment (TQSM).


RESULTS
The TQSM's parameters of ten BYHW decoction extract, such as AUC(T) was 1.976 x 10(7) microV x s, AUCPW(T) was 3.807 x 10(4) microV x s/mg, MCRT(T) was 13.72 min, VCRT(T) was 15.74 min2, and total quantum concentration was 519.0 mg/mL.


CONCLUSIONS
The total quantum statistic moment can be used to characterize the curve of chromatographic fingerprints with expressive parameters above, also to quantitative analyses by AUC(T) and qualitative analyses by AUCPW(T), MCRT(T) and VCRT(T).
College of Pharmacy, Hunan University of Traditional Chinese Medicine, Changsha 410208, China.
Jin
J
Zhou
Kai-Wen
KW
Deng
Fu-Yuan
FY
He
Wen-Long
WL
Liu
D019540:Area Under Curve; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D008962:Models, Theoretical; D010946:Plants, Medicinal / Q000737:chemistry*
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C460102:buyang huanwu