Influence of peritoneal dialysis solution on measurements of fluid status by bioimpedance spectroscopy.
OBJECTIVE
The accurate estimation of volume status is a central problem in dialysis patients. Recently, a bioimpedance spectroscopy (BIS) device (BCM Body Composition Monitor FMC, Germany) has attained growing interest in this regard. By processing the raw data for extracellular water (ECW) and intracellular water (ICW) by means of a validated body composition model, this device allows a quantification of the individual fluid overload (FO) compared to a representative healthy population. In this study, we addressed the issue whether the presence of peritoneal dialysate has an impact on measurements of FO by BIS in PD patients.


RESULTS
Forty-two BIS measurements using the BCM device were performed both in the absence (D-) and presence (D+) of peritoneal dialysate in 17 stable PD patients. Data for ECW, ICW and FO (D+; D-) were analyzed by paired t test and linear regression. Mean FO was 0.99 ± 1.17 L in D- and 0.94 ± 1.27 in D+ (p = n.s. paired t test). Linear regression demonstrated an excellent degree of conformity between FO (D-) and FO (D+) (r (2) = 0.93).


CONCLUSIONS
The presence of peritoneal fluid in PD patients has a negligible influence on measurements of FO by BIS. The BIS measurements can be therefore conveniently and reliably done without emptying the peritoneal cavity; this may facilitate the use of BIS in this particular group of patients.
Division of Nephrology, Department of Medicine, University Hospital Carl-Gustav-Carus, Dresden, Germany. simon.parmentier@uniklinikum-dresden.de
Simon Paul
SP
Parmentier
Holger
H
Schirutschke
Bertram
B
Schmitt
Jens
J
Schewe
Kay
K
Herbrig
Frank
F
Pistrosch
Jens
J
Passauer
D001823:Body Composition; D015314:Dialysis Solutions / Q000494:pharmacology*; D058266:Dielectric Spectroscopy; D045604:Extracellular Fluid; D006801:Humans; D007424:Intracellular Fluid; D016014:Linear Models; D010530:Peritoneal Dialysis
D015314:Dialysis Solutions