Histopathological and immunohistochemical study of laterocervical lymph node metastases of unknown primary origin.
In this study, we examined histopathologically and immunohistochemically 24 cases of laterocervical lymph node metastases with unknown primary origin. For immunohistochemical study, we used a large panel of antibodies represented by CK7, CK19, CK20, CKAE1/AE3, CK34betaE12, TTF1, HBME-1, CEA, MUC5AC and EBV. In the cases studied tumors accompanied by seemingly primitive adenopathies were located in the thyroid, lung, esophagus, stomach, rhinopharynx, hypopharynx, oropharynx and larynx.
Department of ENT, University of Medicine and Pharmacy of Craiova, Craiova, Romania. ramona_denise@yahoo.com
Ramona Denise
RD
Mălin
Elena
E
Ioniţă
I
I
Osman
Carmen Aurelia
CA
Mogoantă
Luminiţa
L
Cioroianu
S
S
Ciolofan
F
F
Anghelina
Mădălina
M
Enăchescu
D002294:Carcinoma, Squamous Cell / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009369:Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D009382:Neoplasms, Unknown Primary / Q000378:metabolism / Q000473:pathology / Q000601:surgery