Controllable anchoring of gold nanoparticles to polypyrrole nanofibers by hydrogen bonding and their application in nonenzymatic glucose sensors.
An enzymeless glucose biosensor based on polypyrrole nanofibers-supporting Au nanoparticles (Au/PPyNFs) was investigated in this study. The Au/PPyNFs heterogeneous composite materials were synthesized in-situ via hydrogen bonding interactions for the assembly of polyethyleneimine (PEI) on the surface of polypyrrole nanofibers (PPyNFs). By changing the molar ratio of PPy to HAuCl(4), Au/PPyNFs with different Au loadings were obtained. The morphology and composition of Au/PPyNFs were characterized using SEM, TEM, FTIR, XRD and XPS, respectively. The hybrids exhibited a high electrocatalytic activity toward glucose oxidation, which is prerequisite for the catalysts to be applied in amperometric glucose sensors. By using the nonenzymatic glucose sensor based on Au/PPyNFs, 0.2-13 mM glucose can be detected with a sensitivity of 1.003 μA cm(-2)mM(-1) and a good linearity (R(2)=0.9993) between current density and glucose concentration. The proposed glucose sensor provides a promising strategy to construct fast, sensitive, and anti-interfering amperometric sensors for early diagnosis and prevention of diabetes.
Changchun Institute of Applied Chemistry, Graduate School of Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, PR China.
Cuiling
C
Li
Yi
Y
Su
Xiangyu
X
Lv
Hailong
H
Xia
Hongjun
H
Shi
Xiangguang
X
Yang
Jinqiang
J
Zhang
Yujiang
Y
Wang
D015374:Biosensing Techniques / Q000379:methods*; D055664:Electrochemical Techniques / Q000379:methods; D005947:Glucose / Q000032:analysis*; D006046:Gold / Q000737:chemistry*; D057139:Nanofibers / Q000737:chemistry* / Q000648:ultrastructure; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010084:Oxidation-Reduction; D011108:Polymers / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*; D012680:Sensitivity and Specificity
D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole; D006046:Gold; D005947:Glucose