Improvement in the high-fat diet-induced dyslipidemia and adiponectin levels by fish oil feeding combined with food restriction in obese KKAy mice.
The effect on weight reduction of fish oil combined with food restriction in comparison with that of beef tallow was investigated in high-fat diet-induced obese KKAy mice. Although the reduction of body and white adipose tissue weight was similar in the two groups, fish oil increased adiponectin levels in the plasma, improved dyslipidemia accompanied by suppression of lipid synthesis in the liver when compared with beef tallow.
Department of Clinical Dietetics and Human Nutrition, Faculty of Pharmaceutical Sciences, Josai University, Sakado, Saitama, Japan.
Masaki
M
Wakutsu
Nobuyo
N
Tsunoda
Yasuki
Y
Mochi
Mitsuki
M
Numajiri
Sachiko
S
Shiba
Etsuko
E
Muraki
Keizo
K
Kasono
D052242:Adiponectin / Q000097:blood; D052436:Adipose Tissue, White / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002417:Cattle; D059305:Diet, High-Fat; D004041:Dietary Fats / Q000008:administration & dosage*; D050171:Dyslipidemias / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D005223:Fats / Q000494:pharmacology*; D005395:Fish Oils / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D051379:Mice; D008820:Mice, Obese; D015431:Weight Loss / Q000187:drug effects
D052242:Adiponectin; D004041:Dietary Fats; D005223:Fats; D005395:Fish Oils; C013698:tallow