Effects of a soybean nutrition bar on the postprandial blood glucose and lipid levels in patients with diabetes mellitus.
We investigated the influence of a soybean nutrition bar made from whole soy powder on the blood glucose, insulin and lipid levels in comparison with a test cookie with the same amount of energy in patients with diabetes mellitus. In the cross-over designed study, meal tolerance tests using the soybean nutrition bar and test cookie were performed. Two kinds of test meals were used: Study 1 80 kcal, Study 2 592 kcal. The blood glucose response was significantly lower in the soybean nutrition bar trial than in the cookie trial (Studies 1 and 2, p < 0.001). The blood insulin response was also significantly lower in the soybean nutrition bar trial than in the cookie trial (Study 2, p < 0.001). The blood triglyceride and non-esterified fatty acid responses were not significantly different between the two trials, nor were the changes in breath H₂ enrichment (Study 2). The soybean nutrition bar did not induce postprandial hyperglycaemia in diabetic patients unlike the isoenergetic test cookies.
Department of General Medicine and Emergency Care, Toho University School of Medicine, Tokyo, Japan. foo@eb.mbn.or.jp
Yoshihisa
Y
Urita
Tsuneyuki
T
Noda
Daisuke
D
Watanabe
Soh
S
Iwashita
Koichiro
K
Hamada
Motonobu
M
Sugimoto
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000032:analysis; D018592:Cross-Over Studies; D003920:Diabetes Mellitus / Q000097:blood / Q000178:diet therapy* / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000178:diet therapy / Q000378:metabolism; D050171:Dyslipidemias / Q000517:prevention & control*; D005260:Female; D038321:Glycemic Index; D006801:Humans; D006943:Hyperglycemia / Q000517:prevention & control*; D007333:Insulin Resistance; D007564:Japan; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D062410:Snacks; D045730:Soy Foods
D001786:Blood Glucose; D008055:Lipids