Angioembolization for pelvic hemorrhage control: results from the German pelvic injury register.
BACKGROUND
Hemorrhage from pelvic vessels is a potentially lethal complication of pelvic fractures. There is ongoing controversy on the ideal treatment strategy for patients with pelvic hemorrhage. The aim of the study was to analyze the role of angiography and subsequent embolization in patients with pelvic fractures and computed tomography scan-proven vascular injuries.


METHODS
The data from the prospective multicenter German pelvic injury registry were analyzed. Of 5,040 patients with pelvic fractures, 152 patients with associated vascular injuries were identified. Patients undergoing angioembolization (n = 17) were compared with those undergoing conventional measures for hemorrhage control (n = 135) with regard to demographic and physiologic parameters, fracture type distribution, and treatment measures. Outcome measures were mortality, requirement for blood transfusions, complications, and hospital length of stay.


RESULTS
Embolization and nonembolization groups were comparable with regard to age, sex, Injury Severity Score, Hannover Polytrauma Score, initial hemoglobin levels, blood pressure, fracture distribution, and conventional measures. Blood transfusion requirement was significantly prolonged in the embolization group. This resulted in a higher adult respiratory distress syndrome incidence and a tendency toward increased multiple organ failure rate in this group. There was no significant difference in overall mortality rate when compared with the nonembolization group (17.6% vs. 32.6%, respectively; p = 0.27). None of the patients undergoing embolization died from exsanguination when compared with 20.6% in the nonembolization group (p = 0.038).


CONCLUSIONS
Angioembolization alongside with conventional measures is an effective complementary means for hemorrhage control in patients sustaining pelvic fracture-related vascular lesions. It might prove even more effective when performed early enough to avoid prolonged blood transfusion requirement. Further studies without the mentioned limitations of the study are desired.


METHODS
Therapeutic study, level IV.
Department for Orthopedic Surgery and Traumatology, Freiburg University Medical Center, Freiburg, Germany.
Oliver
O
Hauschild
Emin
E
Aghayev
Johanna
J
von Heyden
Peter C
PC
Strohm
Ulf
U
Culemann
Tim
T
Pohlemann
Norbert P
NP
Suedkamp
Hagen
H
Schmal
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography / Q000379:methods; D001803:Blood Transfusion / Q000706:statistics & numerical data; D015331:Cohort Studies; D004621:Embolization, Therapeutic / Q000379:methods* / Q000401:mortality; D005260:Female; D005593:Fracture Fixation, Internal / Q000379:methods / Q000401:mortality; D050723:Fractures, Bone / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D005858:Germany; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D017052:Hospital Mortality; D006801:Humans; D015601:Injury Severity Score; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010384:Pelvic Bones / Q000000981:diagnostic imaging / Q000293:injuries*; D011379:Prognosis; D011446:Prospective Studies; D012016:Reference Values; D012042:Registries; D012187:Retroperitoneal Space; D018570:Risk Assessment; D015503:Surgical Sponges; D015996:Survival Rate; D014193:Trauma Centers; D016896:Treatment Outcome; D057772:Vascular System Injuries / Q000000981:diagnostic imaging / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D055815:Young Adult