[Study on chemical constituents of Artemisia sphaerocephala].
Further study on the chemical constituents of Artemisia sphaerocephala led to the isolation of fifteen compounds. These compounds were isolated and purified by repeated column chromatography on silica gel and Sephadex LH-20. Their structures were determined by physicochemical properties and spectral data analysis. These compounds were identified as 5-hydroxy-7,4'-dimethoxyflavanone (1), 5-hydroxy-7, 4'-dimethoxyflavone (2), 5-hydroxy-7, 4'-dimethoxyflavanonol (3), 5,3'-dihydroxy-7, 4'-dimethoxyflavanone (4), 5,7-dihydroxy-6,4'-dimethoxyflavone (5), isosakuranetin (6), hesperetin (7), navingenin (8), acacetin (9), chrysoeroil (10), 5,7-dihydroxy-4'-methoxyflavone-6,8-di-C- -glucopyranoside (11), didymin (12), acacetin-7-O-rutinoside (13), piceine (14), and capillarin (15). Compounds 1-3, 5, 7, 8, 10-15 were isolated from this plant for the first time.
Key Laboratory of Natural Medicine and Immuno-Engineering, Henan University, Kaifeng 475004, China. jiezhang@henu.edu.cn
Jie
J
Zhang
Linxi
L
Li
Xiuhua
X
Liu
Yong
Y
Wang
Dongbao
D
Zhao
D019306:Artemisia / Q000737:chemistry*; D002845:Chromatography / Q000379:methods; D047309:Flavones / Q000032:analysis / Q000302:isolation & purification; D005419:Flavonoids / Q000032:analysis / Q000302:isolation & purification; D005960:Glucosides / Q000032:analysis / Q000302:isolation & purification; D010936:Plant Extracts / Q000032:analysis* / Q000302:isolation & purification*
D047309:Flavones; D005419:Flavonoids; D005960:Glucosides; D010936:Plant Extracts; C023717:acacetin; C538973:isosakuranetin