[Space-occupying lesion of the ribs].
An osteolytic tumor of the 7(th) rib was surgically removed from a 40-year-old patient. Immunohistochemical investigations showed that neither epithelial markers nor B and T cell markers were expressed in the tumor tissue; however, there was strong expression of VS38 and vimentin. These results were compatible with a solitary plasmocytoma of the bone. Further immunohistochemical investigations detected an expression of the melanoma markers S-100 and melan-A. The diagnosis of a metastasis of an amelanotic malignant melanoma could therefore be verified.
Pathologisches Institut Recklinghausen, Mühlenstraße 31, 45659, Recklinghausen, Deutschland. kjschmitz@pathologie-re.de
K J
KJ
Schmitz
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D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001859:Bone Neoplasms / Q000473:pathology* / Q000556:secondary* / Q000601:surgery; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D018328:Melanoma, Amelanotic / Q000473:pathology* / Q000556:secondary* / Q000601:surgery; D009382:Neoplasms, Unknown Primary / Q000473:pathology* / Q000601:surgery*; D010954:Plasmacytoma / Q000473:pathology* / Q000601:surgery*; D012272:Ribs / Q000473:pathology*
D014408:Biomarkers, Tumor