[New method for industrial microbial strains improvement--construction of dominant genome-simplified strains--a review].
The necessity and feasibility of constructing dominant genome-simplified strains for industrial production were introduced, based on some successful cases in which the production efficiency was improved after simplifying the genome of strains. The principle and process of genome simplifying were summarized. In addition, the perspective of dominant genome-simplified strains for industrial production was discussed, combined with authors' own studies.
Key Laboratory of Molecular Microbiology and Technology for Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China. wyy2589@163.com
Yuanyuan
Y
Wang
Wenbin
W
Guo
Cunjiang
C
Song
D001419:Bacteria / Q000235:genetics* / Q000378:metabolism; D005818:Genetic Engineering / Q000379:methods*; D059646:Genome Size; D016680:Genome, Bacterial; D007218:Industrial Microbiology