Non-invasive ventilation in an elderly population admitted to a respiratory monitoring unit: causes, complications and one-year evolution.
OBJECTIVE
To determine the usefulness of non-invasive ventilation (NIV) in elderly patients (≥75) admitted to a respiratory monitoring unit (RMU) during hospitalization and 1 year later in comparison with the results from the younger age group (<75).


METHODS
Ours is a prospective observational study carried out at the Hospital Universitario La Princesa (Madrid, Spain). We recruited all patients who were ≥75 years old and were admitted to our RMU during the period 2008-2009 with respiratory acidosis (pH<7.35 and PaCO(2)>45 mmHg) requiring NIV. We gathered data for basic variables as well as sociodemographics, history of previous pathologies, reason for hospitalization and severity, analysis upon admission and the evolution of blood gases at the start of NIV (within the first hour and after 24 h), complications and evolution at the 1-year follow-up.


RESULTS
Mean age of the sample was 80.6. The Charlson index was 3.27. About half of the patients had some limitation for performing daily activities. The main reasons for admission were COPD exacerbation and heart failure. There were complications in 36% of the cases (11 renal failure and 6 atrial fibrillation). The survival rate at the 1-year follow-up was 63.21%.


CONCLUSIONS
NIV is a good alternative in elderly patients admitted to the hospital with respiratory acidosis. We did not detect differences in mortality during admission between the two groups. The elderly patients were more frequently re-admitted than the younger group in the 6-12 months after hospital discharge. This could be due to their poorer functional state after hospitalization requiring NIV.
Servicio de Neumología, Hospital Universitario La Princesa, Madrid, Spain. gsegrelles@hotmail.com
Gonzalo
G
Segrelles Calvo
Enrique
E
Zamora García
Rosa
R
Girón Moreno
Emma
E
Vázquez Espinosa
Rosa Mar
RM
Gómez Punter
Gilda
G
Fernandes Vasconcelos
Claudia
C
Valenzuela
Julio
J
Ancochea Bermúdez
D000142:Acidosis, Respiratory / Q000097:blood / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D000203:Activities of Daily Living; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D019468:Disease Management; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000150:complications; D017052:Hospital Mortality; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D008297:Male; D063087:Noninvasive Ventilation / Q000706:statistics & numerical data; D010100:Oxygen / Q000097:blood; D010102:Oxygen Inhalation Therapy; D010359:Patient Readmission / Q000706:statistics & numerical data; D011446:Prospective Studies; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications; D012124:Respiratory Care Units / Q000706:statistics & numerical data; D013030:Spain / Q000453:epidemiology; D062606:Tertiary Care Centers / Q000706:statistics & numerical data; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
D014662:Vasoconstrictor Agents; D010100:Oxygen