International guidelines for clinical trials with pediculicides.
Pediculosis capitis, infestation with head lice, is common in all human societies. Chemical pediculicides are often used to control head louse infestations, particularly in wealthy communities. A significant number of different protocols have been used to test the efficacy and safety of pediculicides in clinical trials; this constrains scientific comparison of the evidence for efficacy of the different pediculicides. Here we recommend protocols for clinical trials of the efficacy and safety of single-, two-, and three-treatment interventions.
Parasitology Section, School of Chemistry and Molecular Biosciences, The University of Queensland, Queensland, Australia. s.barker@uq.edu.au
Stephen C
SC
Barker
Ian
I
Burgess
Terri L
TL
Meinking
Kostas Y
KY
Mumcuoglu
D000818:Animals; D002986:Clinical Trials as Topic / Q000592:standards*; D017408:Guidelines as Topic; D006801:Humans; D007306:Insecticides / Q000009:adverse effects / Q000627:therapeutic use*; D010373:Lice Infestations / Q000188:drug therapy*; D010374:Pediculus; D012536:Scalp Dermatoses / Q000188:drug therapy*
D007306:Insecticides