Keratocystic odontogenic tumor: a recurrence analysis of clinical and radiographic parameters.
OBJECTIVE
The aim of this study was to analyze the clinical and radiologic features of keratocystic odontogenic tumors (KCOT) and their recurrence patterns.


METHODS
The authors undertook a retrospective analysis of 145 histopathologically proven KCOT. Recurrence was analyzed for age, sex, site, size, radiographic appearance, treatment, and association with nevoid basal cell carcinoma syndrome (NBCCS).


RESULTS
The mean age at presentation was 34.5 years, with a male predilection. Most KCOT (75.2%) were located in the mandible, with the posterior regions being most commonly affected. Radiographically, the majority of KCOT were unilocular (71.0%) in appearance, and 16.5% had scalloped margins. There was no significant association of recurrence rate with sex, site, size, radiographic appearance, and treatment. However, KCOT had significantly higher recurrence associated with age (P < .01) and NBCCS (P = .001).


CONCLUSIONS
Most clinical and radiologic features of KCOT were similar to earlier reports. Recurrence was significantly associated with second and eighth decades of life and NBCCS.
Department of Diagnostics and Radiology, Faculty of Dentistry, University of Western Cape, Cape Town, South Africa.
Fadi
F
Titinchi
Christoffel J
CJ
Nortje
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001478:Basal Cell Nevus Syndrome / Q000000981:diagnostic imaging / Q000473:pathology*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009808:Odontogenic Tumors / Q000000981:diagnostic imaging / Q000473:pathology*; D011862:Radiography, Panoramic; D012189:Retrospective Studies; D012307:Risk Factors