Microtubules: MEC-17 moonlights in the lumen.
New research characterizes a tubulin acetyltransferase that acts inside the microtubule lumen and has two separable activities that greatly affect microtubule architecture and functionality.
Department of Cellular Biology, University of Georgia, Athens, Georgia 30602, USA. jgaertig@uga.edu
Jacek
J
Gaertig
Dorota
D
Wloga
D000123:Acetyltransferases / Q000378:metabolism*; D000818:Animals; D017173:Caenorhabditis elegans / Q000502:physiology*; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism*; D008465:Mechanoreceptors / Q000378:metabolism* / Q000502:physiology*; D008870:Microtubules / Q000201:enzymology* / Q000502:physiology*; D008958:Models, Molecular; D011499:Protein Processing, Post-Translational / Q000502:physiology*; D014404:Tubulin / Q000378:metabolism*
D029742:Caenorhabditis elegans Proteins; C118234:MEC-12 protein, C elegans; D014404:Tubulin; D000123:Acetyltransferases; C552528:MEC-17 protein, C elegans