SLE with diffuse alveolar hemorrhage, microangiopathic hemolytic anemia and acute renal failure.
In SLE patients with diffuse alveolar hemorrhage (DAH) and acute renal failure (ARF), the most common associated renal injury is proliferative lupus nephritis. We report a case of a young SLE patient with DAH and ARF who was successfully treated with a course of therapeutic plasma exchange (TPE) plus pulse IV cyclophosphamide. Kidney biopsy revealed an alternative diagnosis.
Faculty of Medicine, Burapha University, Thailand. syongsiri@yahoo.com
Somchai
S
Yongsiri
Jiranuch
J
Thammakumpee
Natthaphon
N
Annanon
D058186:Acute Kidney Injury / Q000150:complications* / Q000628:therapy; D000328:Adult; D000743:Anemia, Hemolytic / Q000150:complications* / Q000628:therapy; D001706:Biopsy; D003520:Cyclophosphamide / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D007678:Kidney Glomerulus / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000628:therapy; D008181:Lupus Nephritis / Q000175:diagnosis; D010951:Plasma Exchange / Q000379:methods; D006435:Renal Dialysis
D003520:Cyclophosphamide