Regenerative materials that facilitate wound healing.
Wounds and damaged tissue become problematic when the tissue repair process does not proceed in a normal manner. Standard treatment of wounds entails topical dressings and devices in conjunction with good wound care practices. Good practices adequately support healing in most patients. Difficult, chronic, or recalcitrant wounds may require the use of more advanced technologies. Wounds that are full thickness or present with the absence of a matrix, may particularly benefit from regenerative materials. This article focuses on the use of cellular and acellular materials as well as chemical constructs to support granulation, tissue repair, and wound closure.
Division of Trauma, Department of Surgery, Wound Treatment and Research Center, University of California San Diego, 200 West Arbor Drive #8896, San Diego, CA 92103-8896, USA. gmulder01@aol.com
Gerit
G
Mulder
Kelly
K
Wallin
Mayer
M
Tenenhaus
D001458:Bandages; D002908:Chronic Disease; D020099:Coated Materials, Biocompatible / Q000627:therapeutic use; D048909:Diabetes Complications / Q000628:therapy; D005109:Extracellular Matrix / Q000378:metabolism; D016523:Foot Ulcer / Q000628:therapy; D006801:Humans; D007871:Leg Ulcer / Q000628:therapy; D058629:Plasma Skin Regeneration; D012883:Skin Ulcer / Q000628:therapy; D017768:Skin, Artificial; D014945:Wound Healing / Q000502:physiology*; D014947:Wounds and Injuries / Q000628:therapy*
D020099:Coated Materials, Biocompatible; C512800:TransCyte