Neospora caninum in Estonian dairy herds in relation to herd size, reproduction parameters, bovine virus diarrhoea virus, and bovine herpes virus 1.
Cows infected with the tissue parasite Neospora caninum (Nc) are more likely to abort or give birth to calves with neurological disorders. The known infection routes are transplacentally and by consumption of oocysts shed by the definitive host, the dog. It has been hypothesised, that dormant stages of persistent Nc infection may be reactivated by immunosuppression mechanisms such as pathogenic invasions as bovine herpes virus 1 (BHV1) and bovine virus diarrhoea virus (BVDV). The study was set to give the first prevalence data on Nc from Estonian dairy herds in both animal as well as herd level. In addition, association between herd size and Nc, and association of Nc with abortion incidence (Ab), stillbirth incidence (Sb), insemination index (II), and calving interval (CaI) in the presence of BHV1 and BVDV was studied. Blood samples from 1973 animals from 100 herds were collected in 2006-2008, and 320 bulk tank milk (BTM) samples were collected in 2007. Antibodies against Nc was found in 2.5 ± 0.4% (95% CI) of the animals and at least one positive animal was found in 37.0 ± 4.7% (95% CI) of the herds. In addition, Nc antibodies were detected in 16.3 ± 2.0% (95% CI) of the tested BTM. Large herds (≥ 200 animals) were less likely to have seropositive animals for Nc. Logistic regression models showed that herds with more than one animal seropositive for Nc had significantly higher odds ratio of abortion incidence (OR: 11.92, 1.18-120.18 95% CI, p=0.036) and tendency of having more stillbirths (OR: 5.52, 0.87-35.02 95% CI, p=0.07). On the other hand one Nc seropostive cow in the herd was associated with lower odds ratio (OR: 0.22, 0.05-0.91 95% CI, p=0.04) of higher calving intervals. Estonian prevalence results reflect observations in the region. No evidence was found of the pathogens were affecting fertility variables through interactions but independently BHV1 and Nc had an impact on the abortion.
Estonian University of Life Sciences, Institute of Veterinary Medicine and Animal Sciences, Kreutzwaldi 62, 51014 Tartu, Estonia. brian.lassen@gmail.com
Brian
B
Lassen
Toomas
T
Orro
Annely
A
Aleksejev
Kerli
K
Raaperi
Toivo
T
Järvis
Arvo
A
Viltrop
D000034:Abortion, Veterinary / Q000469:parasitology; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000150:complications / Q000453:epidemiology / Q000821:virology; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology* / Q000469:parasitology / Q000821:virology; D003048:Coccidiosis / Q000150:complications / Q000453:epidemiology / Q000469:parasitology / Q000662:veterinary*; D001908:Diarrhea Viruses, Bovine Viral / Q000276:immunology* / Q000302:isolation & purification; D004957:Estonia / Q000453:epidemiology; D005260:Female; D007242:Herpesvirus 1, Bovine / Q000276:immunology* / Q000302:isolation & purification; D015994:Incidence; D007241:Infectious Bovine Rhinotracheitis / Q000150:complications / Q000453:epidemiology / Q000821:virology; D016015:Logistic Models; D008892:Milk / Q000276:immunology / Q000469:parasitology / Q000821:virology; D018688:Neospora / Q000276:immunology* / Q000302:isolation & purification; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000453:epidemiology / Q000469:parasitology / Q000662:veterinary*; D015995:Prevalence; D012098:Reproduction; D050497:Stillbirth / Q000662:veterinary
D000913:Antibodies, Protozoan; D000914:Antibodies, Viral