Primary esophageal adenocarcinoma arising from heterotopic gastric mucosa: report of a case.
Adenocarcinoma arising from heterotopic gastric mucosa (HGM) is exceedingly rare. This report presents the case of a 57-year-old male who presented with the chief complaint of dysphagia. Endoscopy and computed tomography revealed a locally advanced tumor of the cervical esophagus and swollen mediastinal lymph nodes. He underwent chemoradiotherapy followed by esophagectomy with three-field lymph node dissection. The resected tumor was a circumferentially scarred lesion located 1.5 cm from the proximal margin. The tumor was identified to be a well-differentiated adenocarcinoma arising from HGM with invasion to the muscularis propria. Postoperative chemoradiotherapy was performed because positive surgical margins were observed in the resected tissue. The patient has remained alive for more than 4 years after surgery, without any evidence of recurrence.
Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba 260-8670, Japan. n-akanuma@chiba-u.jp
Naoki
N
Akanuma
Isamu
I
Hoshino
Yasunori
Y
Akutsu
Kiyohiko
K
Shuto
Toru
T
Shiratori
Tsuguaki
T
Kono
Masaya
M
Uesato
Asami
A
Sato
Yuka
Y
Isozaki
Tetsuro
T
Maruyama
Nobuyoshi
N
Takeshita
Hisahiro
H
Matsubara
D000230:Adenocarcinoma / Q000473:pathology*; D002828:Choristoma / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000473:pathology*; D005753:Gastric Mucosa; D006801:Humans; D008297:Male; D008875:Middle Aged