[Light pollution increases morbidity and mortality rate from different causes in male rats].
The influence of different light regimes (constant light--LL; constant darkness--DD; standard light regime--LD, 12 hours light 12 hours darkness; natural lightening of the North-West of Russia--NL) on the dynamics of life's morbidity rate, spontaneous tumorigenesis and frequency of some kinds of non-tumor pathology revealed at the post-mortem examination of male rats was studied. It was found out that the maintenance of animals at LL and NL conditions led to the increase of the number of infectious diseases, substantially faster development of spontaneous tumors and the increase of non-tumor diseases in comparison with the animals kept at LD (standard light) regime. Light deprivation (DD) led to substantial reduction of development of new growth, of non-tumor and infectious diseases in comparison with the similar parameters in standard light regime.
A V
AV
Bukalev
I A
IA
Vinogradova
M A
MA
Zabezhinskiĭ
A V
AV
Semenchenko
V N
VN
Anisimov
D000375:Aging / Q000473:pathology; D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology; D003624:Darkness; D004194:Disease / Q000209:etiology*; D008027:Light / Q000009:adverse effects*; D008297:Male; D009017:Morbidity / Q000639:trends; D009026:Mortality / Q000639:trends; D051381:Rats