[Application of network pharmacology and high through-put technology on active compounds screening from traditional Chinese medicine].
OBJECTIVE
To solve the difficult in the active compounds screening from traditional Chinese medicines (TCM).


METHODS
According to preliminary lab results and related literature, systematic analysis of the high-throughput technology was made.


RESULTS
Technologies of rapid preparation, high-throughput screening and biochip, together with the thought of drug target network, will contribute to TCM research on active ingredients screening, toxic components exclusion and molecular mechanisms. They are key technologies and ideas for modernization of TCM and research of TCM network pharmacology.


CONCLUSIONS
High throughput technology and network pharmacology-related technologies will provide new ideas and key methods for active compounds screening from TCM.
National Center of China for Minority Traditional Medical Research, Minzu University of China, Beijing 100081, China.
Qingshan
Q
Liu
Ziqian
Z
Zhang
Liang
L
Fang
Yifan
Y
Jiang
Xiaoying
X
Yin
D016503:Drug Delivery Systems / Q000379:methods; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000737:chemistry / Q000302:isolation & purification*; D006801:Humans; D008516:Medicine, Chinese Traditional; D010600:Pharmacology / Q000379:methods*; D013678:Technology, Pharmaceutical / Q000379:methods*
D004365:Drugs, Chinese Herbal