Asymmetric synthesis and biosynthetic implications of (+)-fusarisetin A.
Starting from equisetin, the asymmetric synthesis of (+)-fusarisetin A has been accomplished in a one-pot transformation including a biomimetic oxidation and an intramolecular Diels-Alder/Roskamp reaction. Peroxyfusarisetin is proposed as a plausible biosynthetic intermediate based on studies of the oxidation of equisetin.
Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663N Zhongshan Road, Shanghai 200062, China.
Jun
J
Yin
Cheng
C
Wang
Lili
L
Kong
Shujun
S
Cai
Shuanhu
S
Gao
D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism*; D008968:Molecular Conformation; D013237:Stereoisomerism
D006576:Heterocyclic Compounds, 4 or More Rings; C572422:fusarisetin A