Spitz nevus and Reed nevus.
Spitz and Reed nevi, also called spindle and/or epithelioid cell nevi, are a special group of melanocytic lesions due to their peculiar clinical, dermoscopic and histopathological features. The study of these nevi is of great interest because both their nomenclature and classification are still a matter of discussion. Most importantly, the difficulty to differentiate them from melanoma can lead to inadequate therapies. In this context, dermoscopy, a link between clinical and anatomopathological examinations, appears as a helpful diagnostic tool whose accuracy can reach 93%. "Borderline" lesions are still a great challenge and object of research, including molecular studies. The present study explores the relevant characteristics of these nevi, with emphasis on dermoscopic findings, aiming at understanding their natural history, as well as discussing treatment and patient follow-up.
ABC School of Medicine, Santo André, SP, Brazil. alessandraderma@hotmail.com
Alessandra
A
Yoradjian
Mílvia Maria Simões e Silva
MM
Enokihara
Francisco Macedo
FM
Paschoal
D003937:Diagnosis, Differential; D006801:Humans; D018332:Nevus, Epithelioid and Spindle Cell / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D018331:Nevus, Spindle Cell / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D011379:Prognosis; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy