Monosodium urate (MSU) crystals increase gout associated coronary heart disease (CHD) risk through the activation of NLRP3 inflammasome.
Jia
J
He
Yang
Y
Yang
Dao-Quan
DQ
Peng
D002352:Carrier Proteins / Q000378:metabolism*; D003327:Coronary Disease / Q000209:etiology*; D003460:Crystallization; D006073:Gout / Q000150:complications*; D006801:Humans; D058847:Inflammasomes / Q000378:metabolism*; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; D012306:Risk; D014527:Uric Acid / Q000097:blood* / Q000737:chemistry*
D002352:Carrier Proteins; D058847:Inflammasomes; D000071199:NLR Family, Pyrin Domain-Containing 3 Protein; C453881:NLRP3 protein, human; D014527:Uric Acid