Straightforward acid-catalyzed synthesis of pyrrolyldipyrromethenes.
Three for one: Pyrrolyldipyrromethenes having different functional groups were efficiently synthesized from POCl(3)-promoted condensations between 5-chloro-2-formylpyrrole or isoindole derivatives and suitable pyrrole or indole fragments through a novel nucleophilic aromatic substitution of the initially formed protonated azafulvene rings.
Laboratory of Functional Molecular Solids, Ministry of Education, School of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241000, China.
Changjiang
C
Yu
Lijuan
L
Jiao
Xujun
X
Tan
Jun
J
Wang
Yajun
Y
Xu
Yangchun
Y
Wu
Gaosheng
G
Yang
Zhaoyun
Z
Wang
Erhong
E
Hao
D002384:Catalysis; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D017553:Phosphorus Compounds / Q000737:chemistry*; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry
D017553:Phosphorus Compounds; D011758:Pyrroles; C013196:phosphoryl chloride