Geriatric veterinary pharmacology.
Geriatric dogs and cats are an important group of patients in veterinary medicine. Healthy geriatric patients have similar physiology and presumably pharmacology as healthy adult animals. Geriatric patients with subclinical organ dysfunction are overtly healthy but have some organ dysfunction that may alter the clinical pharmacology of some drugs. Geriatric patients with an overt disease are expected to have altered drug pharmacology for some drugs based on the underlying disease. Diseases including cardiovascular, renal, hepatic, osteoarthritis, neurologic, and neoplastic are expected in the geriatric population and discussed, including the effects of the underlying disease and potential drug-drug interactions.
Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, 228 Coles Hall, Manhattan, KS 66506, USA. kukanich@ksu.edu
Butch
B
Kukanich
D000375:Aging / Q000473:pathology / Q000502:physiology*; D000818:Animals; D001682:Biological Availability; D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000662:veterinary; D002371:Cat Diseases / Q000188:drug therapy* / Q000378:metabolism; D002415:Cats; D004283:Dog Diseases / Q000188:drug therapy* / Q000378:metabolism; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005853:Geriatrics; D007408:Intestinal Absorption; D007674:Kidney Diseases / Q000188:drug therapy / Q000662:veterinary; D008107:Liver Diseases / Q000188:drug therapy / Q000662:veterinary; D016896:Treatment Outcome; D019155:Veterinary Drugs / Q000493:pharmacokinetics* / Q000494:pharmacology*
D019155:Veterinary Drugs