Coronary artery aneurysm after implantation of an endothelial progenitor cell capturing stent.
The Genous™ stent coated with anti-CD34 antibodies has been designed to accelerate healing of the vessel by attracting circulating endothelial progenitor cells. Rapid restoration of a functional endothelial layer with a full coverage of the stent struts aims to minimise arterial injury after coronary stenting and to prevent thrombus formation and neointima proliferation. We report a case of a 56 year-old man who developed a coronary artery aneurysm after the implantation of a Genous™ stent due to an edge restenosis in sirolimus-eluting stent. We present diagnostics of our patient with the application of intravascular ultrasound and coronary computed tomography angiography, discuss his management, and hypothesise about the pathomechanism of aneurysm formation.
Department of Cardiology and Internal Medicine, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Marcin
M
Rychter
Marek
M
Radomski
Adam
A
Sukiennik
Zbigniew
Z
Serafin
Marek
M
Koziński
Jacek
J
Kubica
D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D003323:Coronary Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology*; D017023:Coronary Angiography; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020123:Sirolimus / Q000008:administration & dosage
D000900:Anti-Bacterial Agents; D020123:Sirolimus