[Lipid-proteinic interaction in erythrocytie and placental membranes in women with insulin resistance].
Disturbances of erythrocyte and placental membrane functiond have been studied in placenta of pregnant women with obesity and diabetes mellitus type 2. The results of this study demonstrate significant metabolic impairments in women with insulin resistance. Changes in lipid spectrum of erythrocyte membranes and decreased activity of antioxidant enzymes obviously contribute to the development of fetoplacental insufficiency. This changes point to necessity of the antioxidant therapy in pregnant women with obesity and diabetes mellitus type 2.
N P
NP
Mikaelian
A A
AA
Terent'ev
A G
AG
Maksina
A V
AV
Mikaelian
S A
SA
Novikova
D000328:Adult; D000975:Antioxidants / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism; D004798:Enzymes / Q000378:metabolism; D004910:Erythrocyte Membrane / Q000737:chemistry / Q000378:metabolism*; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006801:Humans; D007333:Insulin Resistance; D015227:Lipid Peroxidation; D008563:Membrane Lipids / Q000378:metabolism*; D009765:Obesity / Q000378:metabolism*; D010743:Phospholipids / Q000737:chemistry / Q000378:metabolism; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000378:metabolism; D011263:Pregnancy Trimester, Third; D011254:Pregnancy in Diabetics / Q000378:metabolism*; D013974:Thyroxine / Q000378:metabolism; D014284:Triiodothyronine / Q000378:metabolism
D000975:Antioxidants; D004798:Enzymes; D008563:Membrane Lipids; D010743:Phospholipids; D014284:Triiodothyronine; D005954:Glucosephosphate Dehydrogenase; D013974:Thyroxine