Phase-field model for the morphology of monolayer lipid domains.
Phase-separated domains exist in multicomponent lipid monolayers and bilayers. We present here a phase-field model that takes into account the competition between lipid dipole-dipole interactions and line tension to define the domain morphology. A dynamic equation for the phase-field is solved numerically showing stationary non-circular shapes like starfish shapes. This phase-field model could be applied to study the dynamic properties of complex problems like phase segregation in pulmonary surfactant membranes and films.
Department of Cell and Developmental Biology, Center for Genomic Regulation (CRG) and UPF, Barcelona, Spain. felix.campelo@crg.cat
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F
Campelo
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Cruz
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Pérez-Gil
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L
Vázquez
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Hernández-Machado
D008055:Lipids / Q000737:chemistry*; D008958:Models, Molecular; D011663:Pulmonary Surfactants / Q000737:chemistry / Q000378:metabolism; D013816:Thermodynamics
D008055:Lipids; D011663:Pulmonary Surfactants