A glucose biosensor based on TiO2-Graphene composite.
A novel glucose biosensor was developed based on the adsorption of glucose oxidase at a TiO(2)-Graphene (GR) nanocomposite electrode. A TiO(2)-GR composite was synthesized from a colloidal mixture of TiO(2) nanoparticles and graphene oxide (GO) nanosheets by an aerosol assisted self-assembly (AASA). The particle morphology of all TiO(2)-GR composites was spherical in shape. It was observed that micron-sized TiO(2) particles were encapsulated by GR nanosheets and that the degree of encapsulation was proportional to the ratio of GO/TiO(2). The amperometric response of the glucose biosensor fabricated by the TiO(2)-GR composite was linear against a concentration of glucose ranging from 0 to 8mM at -0.6 V. The highest sensitivity was noted at about 6.2 μA/mMcm(2). The as prepared glucose biosensor based on the TiO(2)-GR composite showed higher catalytic performance for glucose redox than a pure TiO(2) and GR biosensor.
Rare Metals Research Center, Korea Institute of Geoscience and Mineral Resources, Daejeon 305-350, Korea. hdjang@kigam.re.kr
Hee Dong
HD
Jang
Sun Kyung
SK
Kim
Hankwon
H
Chang
Ki-Min
KM
Roh
Jeong-Woo
JW
Choi
Jiaxing
J
Huang
D015374:Biosensing Techniques / Q000379:methods*; D055664:Electrochemical Techniques / Q000379:methods; D005947:Glucose / Q000032:analysis* / Q000378:metabolism; D005949:Glucose Oxidase / Q000378:metabolism; D006108:Graphite / Q000737:chemistry*; D053761:Nanocomposites / Q000737:chemistry* / Q000648:ultrastructure; D012680:Sensitivity and Specificity; D014025:Titanium / Q000737:chemistry*
C009495:titanium dioxide; D006108:Graphite; D014025:Titanium; D005949:Glucose Oxidase; D005947:Glucose