Aptamer-based polymerase chain reaction for ultrasensitive cell detection.
A new system was developed for sensitive and selective detection of tumor cells taking advantage of cell-attached aptamers amplified by PCR and output signals amplified by cationic conjugated polymers.
Beijing National Laboratory for Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Jinzhao
J
Song
Fengting
F
Lv
Gaomai
G
Yang
Libing
L
Liu
Qiong
Q
Yang
Shu
S
Wang
D052157:Aptamers, Nucleotide / Q000032:analysis* / Q000378:metabolism; D045744:Cell Line, Tumor; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis* / Q000378:metabolism; D016133:Polymerase Chain Reaction / Q000379:methods; D012680:Sensitivity and Specificity
D052157:Aptamers, Nucleotide