Paroxetine and neonatal withdrawal syndrome.
We report a case of neonatal withdrawal syndrome after in utero exposure to paroxetine 20 mg/day. The infant's symptoms, such as poor neonatal adaptation, respiratory distress, decerebrate posturing, irritability and tremors, commenced soon after birth and persisted for 5 days. All neonates exposed to antidepressants, particularly serotonin reuptake inhibitors (SSRIs), during the last trimester should be followed-up closely for adverse symptoms.
L Sacco Hospital, Department of Pediatrics, Milan, Italy.
Laura
L
Pogliani
Laura
L
Schneider
Dario
D
Dilillo
Francesca
F
Penagini
Gian Vincenzo
GV
Zuccotti
D000328:Adult; D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects*; D003863:Depression / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009357:Neonatal Abstinence Syndrome / Q000175:diagnosis* / Q000209:etiology*; D017374:Paroxetine / Q000009:adverse effects*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects
D018687:Antidepressive Agents, Second-Generation; D017374:Paroxetine