Visceral leishmaniasis mimicking autoimmune hepatitis, primary biliary cirrhosis, and systemic lupus erythematosus overlap.
Visceral leishmaniasis (VL) is a life-threatening infection caused by Leishmania species. In addition to typical clinical findings as fever, hepatosplenomegaly, and cachexia, VL is associated with autoimmune phenomena. To date, VL mimicking or exacerbating various autoimmune diseases have been described, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and autoimmune hepatitis (AIH). Herein, we presented a patient with VL who had overlapping clinical features with SLE, AIH, as well as antimitochondrial antibody (AMA-M2) positive primary biliary cirrhosis.
Department of Clinical Microbiology and Infectious Diseases, Gazi University Hospital Besevler, 06500 Ankara, Turkey. oguzel@gazi.edu.tr
Ozlem Guzel
OG
Tunccan
Abdurrahman
A
Tufan
Gülçin
G
Telli
Nalan
N
Akyürek
Merve
M
Pamukçuoğlu
Güldal
G
Yılmaz
Kenan
K
Hızel
D000328:Adult; D001323:Autoantibodies / Q000097:blood; D001853:Bone Marrow / Q000473:pathology; D003584:Cytological Techniques; D003937:Diagnosis, Differential; D005260:Female; D019693:Hepatitis, Autoimmune / Q000150:complications / Q000473:pathology*; D006651:Histocytochemistry; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000150:complications / Q000175:diagnosis* / Q000473:pathology*; D008099:Liver / Q000473:pathology; D008105:Liver Cirrhosis, Biliary / Q000150:complications / Q000473:pathology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000473:pathology*
D001323:Autoantibodies