A novel and efficient one-pot four-component tandem approach for the synthesis of pyran derivatives.
A series of new pyran derivatives are efficiently synthesized in a one-pot four-component tandem reaction via Suzuki coupling followed by a three-component reaction from readily available 4-bromobenzaldehyde, activated methylene compounds, and carbonyl compounds. Single crystal X-ray structure of the synthesized product is presented. The versatility and efficiency of the proposed methodology has been demonstrated in the synthesis of novel heterocyclic molecules.
Department of Chemistry, Jinan University, Guangzhou 510632, China.
Zhanyi
Z
Zhang
Yijing
Y
Xu
Jia
J
Zheng
Bin
B
Li
Yiqun
Y
Li
D001547:Benzaldehydes / Q000737:chemistry; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D011714:Pyrans / Q000138:chemical synthesis* / Q000737:chemistry*
D001547:Benzaldehydes; D011714:Pyrans; C032175:benzaldehyde