[Anaesthesia and vasomotor tone during CPB: intravenous anaesthetics].
Anaesthesia during CBP is frequently provided using intravenous anaesthetic drugs, particularly propofol. The effects of the different drugs have been studied during CPB. These drugs have an arterial and venous vasodilator effect during CPB which is dose dependent and is more pronounced for propofol. High doses of propofol or thiopental reduce cerebral blood flow but provide no additional neurological protection.
Unité De Réanimation Cardiovasculaire et Thoracique, Pole Anesthésie Réanimation, Hôpital Albert Michallon, BP 217, 38043 Grenoble cedex 9, France. MDurand@CHU- Grenoble.fr
M
M
Durand
D000771:Anesthesia, Intravenous; D018686:Anesthetics, Intravenous / Q000494:pharmacology*; D002315:Cardiopulmonary Bypass; D006801:Humans; D009129:Muscle Tonus / Q000187:drug effects / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology / Q000503:physiopathology; D014666:Vasomotor System / Q000187:drug effects*
D018686:Anesthetics, Intravenous