Development of a new and environment friendly hollow fiber-supported liquid phase microextraction using vesicular aggregate-based supramolecular solvent.
Hollow fiber-based liquid phase microextraction (HF-LPME) using conventional solvents is limited by their relative instability and high volatility. The use of supramolecular solvents as a liquid membrane phase could overcome these inconveniences due to their negligible vapour pressure and high viscosity. In the present study, a novel and highly flexible method was developed based on supramolecular solvents constructed of vesicles of decanoic acid, which were used for the first time as a solvent in HF-LPME. This solvent is produced from the coacervation of decanoic acid aqueous vesicles by the action of tetrabutylammonium (Bu(4)N(+)). In this work, halogenated anilines as model compounds were extracted from water samples into a supramolecular solvent impregnated in the pores and also filled inside the porous polypropylene hollow fiber membrane. The extracted anilines were separated and determined by high-performance liquid chromatography. The technique requires minimal sample preparation time and toxic organic solvent consumption, and provides a significant advantage over conventional analytical methods. The important parameters influencing the extraction efficiency were studied and optimized utilizing two different optimization methods: one variable at a time and the Box-Behnken design. Under the optimum conditions, the preconcentration factors were in the range of 74 to 203. Linearity of the method was obtained in the range of 1.0-100 μg L(-1) with the correlation coefficients of determination (R(2)) ranging from 0.9901 to 0.9986. The limits of detection for the target anilines were 0.5-1.0 μg L(-1). The relative standard deviations varied from 3.9% to 6.0%. The relative recoveries of the three halogenated anilines from water samples at a spiking level of 20.0 μg L(-1) were in the range of 90.4-107.4%.
Department of Chemistry, Faculty of Sciences, Tarbiat Modares University, P.O. Box: 14115-175, Tehran, Iran.
Morteza
M
Moradi
Yadollah
Y
Yamini
Fatemeh
F
Rezaei
Elham
E
Tahmasebi
Ali
A
Esrafili
D000814:Aniline Compounds / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D003652:Decanoic Acids / Q000737:chemistry*; D004867:Equipment Design; D059627:Liquid Phase Microextraction / Q000295:instrumentation* / Q000379:methods*; D046911:Macromolecular Substances / Q000737:chemistry; D010316:Particle Size; D011126:Polypropylenes / Q000737:chemistry*; D016062:Porosity; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D013499:Surface Properties
D000814:Aniline Compounds; D003652:Decanoic Acids; D046911:Macromolecular Substances; D011126:Polypropylenes; D000644:Quaternary Ammonium Compounds; D012997:Solvents; C031071:decanoic acid; C009405:tetrabutylammonium