Analgesic nephropathy as a cause of end-stage renal disease in a 55 year-old Nigerian.
Analgesic nephropathy is a subtle but significant cause of chronic renal failure. There is paucity of data on analgesic nephropathy in Nigeria. This case presentation is to highlight the need to have high index of suspicion in patients at risk of developing analgesic nephropathy. In March 2009 a 55-year-old businessman was referred to the renal unit on account of azotemia by the hematologist who had hitherto managed the patient as a case of refractory anemia. The patient had osteoarthritis for over 10 years and was managed with several analgesic drugs over the same period. He was found to have features suggestive of analgesic nephropathy and had end-stage renal disease. He was commenced on appropriate therapy, and he had a live related kidney transplant six months later. Analgesic nephropathy is preventable and morbidity/mortality can be remarkably reduced with appropriate and prompt intervention.
Department of Medicine, Enugu State University Teaching Hospital, Parklane Enugu, Nigeria. umehughes@yahoo.com
U H
UH
Okafor
E I
EI
Unuigbe
A C
AC
Onwuchekwa
P
P
Emem-Chioma
D000700:Analgesics / Q000009:adverse effects*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000139:chemically induced* / Q000628:therapy; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis
D000700:Analgesics