A microbiological hazard of rural living: Clostridium septicum brain abscess in a child with E coli 0157 associated haemolytic uraemic syndrome.
Clostridium septicum infection in humans is rare and this is the second case report of focal C septicum brain abscesses associated with Escherichia coli 0157 haemolytic uraemic syndrome (HUS). The case presented in a child who lived on a rural farm. The abscesses initially progressed despite 7&emsp14;months of appropriate antibiotic therapy and repeated image-guided aspiration. After definitive resection and prolonged antibiotic therapy, there was no recurrence. This case reminds us of this rare but important neurological complication of HUS and supports consideration of early definitive neurosurgical intervention in similar unusual cases.
Department of Paediatric Infectious Diseases, Great North Childrens Hospital, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK. eleri.williams@nuth.nhs.uk
Eleri J
EJ
Williams
Patrick
P
Mitchell
Dipayan
D
Mitra
Julia E
JE
Clark
D000383:Agriculture; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001922:Brain Abscess / Q000150:complications* / Q000382:microbiology / Q000628:therapy; D002675:Child, Preschool; D003015:Clostridium Infections / Q000150:complications* / Q000382:microbiology; D052557:Clostridium septicum; D004927:Escherichia coli Infections / Q000150:complications*; D019453:Escherichia coli O157; D006463:Hemolytic-Uremic Syndrome / Q000150:complications* / Q000382:microbiology; D006801:Humans; D008297:Male
D000900:Anti-Bacterial Agents