Emergence of metallo-β-lactamase GIM-1 in a clinical isolate of Serratia marcescens.
The metallo-β-lactamase GIM-1 (German imipenemase) has been found so far only in clinical isolates of Pseudomonas aeruginosa from Germany. Here we report the detection of bla(GIM-1) in a clinical strain of Serratia marcescens that was isolated from urine, blood, and wound samples over a period of 20 months. The strain was repeatedly isolated from one patient in two German hospitals and an outpatient department located in the region in which all previously described GIM-1-producing P. aeruginosa strains were identified.
Medizinisches Versorgungszentrum Dr. Stein, Division of Microbiology, Mönchengladbach, Germany. hrieber@labor-stein.de
Heime
H
Rieber
Andre
A
Frontzek
Yvonne
Y
Pfeifer
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D003428:Cross Infection / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D022761:Gene Transfer, Horizontal; D005858:Germany; D006801:Humans; D032023:Integrons / Q000235:genetics; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000235:genetics*; D016868:Serratia Infections / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D012706:Serratia marcescens / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D018440:beta-Lactam Resistance / Q000187:drug effects / Q000235:genetics*; D001618:beta-Lactamases / Q000235:genetics*
D000900:Anti-Bacterial Agents; D001618:beta-Lactamases; C495217:beta-lactamase GIM-1, Pseudomonas aeruginosa