Treatment of dry age-related macular degeneration with dobesilate.
The authors present anatomical and functional evidences of dry age-macular degeneration improvement, after intravitreal treatment with dobesilate. Main outcomes measures were normalisation of retinal structure and function, assessed by optical coherence tomography, fundus-monitored microperimetry, electrophysiology and visual acuity. The effect might be related to the normalisation of the outer retinal architecture.
Departamento de Investigación, IRYCIS, Hospital Universitario Ramón y Cajal, Madrid, Spain. pedro.cuevas@hrc.es
P
P
Cuevas
L A
LA
Outeiriño
J
J
Angulo
G
G
Giménez-Gallego
D002123:Calcium Dobesilate / Q000008:administration & dosage*; D057092:Geographic Atrophy / Q000188:drug therapy*; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D058449:Intravitreal Injections; D008297:Male; D008875:Middle Aged; D041623:Tomography, Optical Coherence
D006490:Hemostatics; D002123:Calcium Dobesilate