Stereoselective synthesis of P-chirogenic dibenzophosphole-boranes via aryne intermediates.
A new aryne-mediated tandem cross-coupling/P-cyclization sequence starting from tertiary phosphine-boranes and 1,2-dibromobenzenes is reported. P-chirogenic dibenzophospholes become accessible in a regio-, chemo-, and diastereoselective way.
Laboratoire de Chimie Moléculaire (UMR CNRS 7509), Université de Strasbourg, ECPM, 25 rue Becquerel, 67087 Strasbourg, France.
Vincent
V
Diemer
Anaïs
A
Berthelot
Jérôme
J
Bayardon
Sylvain
S
Jugé
Frédéric R
FR
Leroux
Françoise
F
Colobert
D000480:Alkynes / Q000737:chemistry*; D001880:Boranes / Q000737:chemistry*; D003500:Cyclization; D008958:Models, Molecular; D015394:Molecular Structure; D010720:Phosphines / Q000737:chemistry*; D013237:Stereoisomerism
D000480:Alkynes; D001880:Boranes; D010720:Phosphines