Aggressive classical Kaposi's sarcoma mimicking malignant lymphoma.
Classical Kaposi's sarcoma is an unusual multifocal neoplasm of vascular endothelial cell origin, and considered a less malignant, slowly-progressing tumor. Although visceral involvement is occasionally seen in HIV/AIDS patients with KS, tumor dissemination to visceral lymph nodes in classical KS is very rare. A 72-year-old woman without any other relevant past medical history presented with anorexia, weight loss, night sweats, and skin eruptions. As the rapid progression of cytopenias and lymphadenopathy were observed, bone marrow biopsy and imaging were performed. Positron emission tomography showed disseminated lymphadenopathy in the cervical, axillary, mediastinal, inguinal, and abdomino-pelvic nodal areas. Inguinal lymph node biopsy was compatible with KS, positive for CD31, CD34, and human herpesvirus-8 by immunohistochemical stain. We report a case of aggressive classical KS mimicking aggressive malignant lymphoma.
Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 108 Pyung-Dong, Chongno-Gu, Seoul, 110-746, South Korea.
Eun Haeng
EH
Jeong
Dong Hoe
DH
Koo
Sang Hyuk
SH
Lee
Ki Bae
KB
Bang
Eun Hye
EH
Park
Ji Soo
JS
Seol
Ji Yong
JY
Lee
Jung Soo
JS
Pyo
Dong Hoon
DH
Kim
Hee Jin
HJ
Lee
Sukjoong
S
Oh
D000368:Aged; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D019288:Herpesvirus 8, Human / Q000302:isolation & purification; D006651:Histocytochemistry; D006801:Humans; D008207:Lymphatic Metastasis; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology*; D049268:Positron-Emission Tomography; D012514:Sarcoma, Kaposi / Q000175:diagnosis / Q000473:pathology* / Q000821:virology