Assessment of whole-genome mapping in a well-defined outbreak of Salmonella enterica serotype Saintpaul.
We investigated the use of whole-genome mapping and pulsed-field gel electrophoresis (PFGE) with isolates from an outbreak of Salmonella enterica serotype Saintpaul. PFGE and whole-genome mapping were concordant with 22 of 23 isolates. Whole-genome mapping is a viable alternative tool for the epidemiological analysis of Salmonella food-borne disease investigations.
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA. pfey@unmc.edu
P D
PD
Fey
P C
PC
Iwen
E B
EB
Zentz
A M
AM
Briska
J K
JK
Henkhaus
K A
KA
Bryant
M A
MA
Larson
R K
RK
Noel
S H
SH
Hinrichs
D002874:Chromosome Mapping / Q000379:methods*; D004196:Disease Outbreaks; D016521:Electrophoresis, Gel, Pulsed-Field / Q000379:methods; D006801:Humans; D017720:Molecular Epidemiology / Q000379:methods; D058889:Molecular Typing / Q000379:methods*; D012480:Salmonella Infections / Q000453:epidemiology* / Q000382:microbiology*; D019779:Salmonella enterica / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification