Molecular identification and in vitro response to antifungal drugs of clinical isolates of Exserohilum.
Exserohilum is an agent of human and animal mycoses. Although classification has been based on a few subtle morphological differences, three species of clinical interest have been traditionally accepted. In this study, by using a multigene sequence analysis, we have demonstrated that Exserohilum longirostratum and E. mcginnisii are probable synonyms of E. rostratum. The isolates tested were mainly from the nasal region. Antifungal susceptibility testing demonstrated high activity of the eight agents tested against this fungus.
Mycology Unit, Medical School and IISPV, Universitat Rovira i Virgili, Reus, Spain.
Keith Cássia
KC
da Cunha
Deanna A
DA
Sutton
Josepa
J
Gené
Javier
J
Capilla
Josep
J
Cano
Josep
J
Guarro
D000935:Antifungal Agents / Q000494:pharmacology*; D001203:Ascomycota / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008826:Microbial Sensitivity Tests; D058885:Multilocus Sequence Typing; D016533:Mycological Typing Techniques; D009181:Mycoses / Q000188:drug therapy* / Q000453:epidemiology / Q000382:microbiology; D009296:Nasal Cavity / Q000382:microbiology*; D014481:United States / Q000453:epidemiology
D000935:Antifungal Agents