[Hair follicle as a novel source of stem cells].
Tissue engineering as a rapidly developing branch of science offers hope for the use of its products in medical practice. Among the components of tissue substitutes are different types of cells, especially stem cells. A promising source of adult stem cells is hair follicles. Development of follicles in the skin takes place even during fetal life. They arise due to the impact of epidermal and mesenchymal cells. The next steps in the formation of hair follicles are under the control of many factors. Hair follicles are the niche of various stem cell populations and are a major source of cells responsible for regeneration of the hair, sebaceous glands and epidermis. The term "hair follicle stem cells" is most often used in relation to the epithelial cell population. Hair follicle stem cell studies are complicated by the fact that these stem cells divide relatively rarely.    The aim of this study is to present the characteristics of cells isolated from the hair follicle in the light of recent research.
Zakład Inżynierii Tkankowej, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, UMK Toruń.
Romana
R
Joachimiak
Anna
A
Bajek
Tomasz
T
Drewa
D000818:Animals; D000078404:Epidermal Cells; D004847:Epithelial Cells / Q000166:cytology; D018859:Hair Follicle / Q000166:cytology* / Q000196:embryology / Q000254:growth & development / Q000637:transplantation*; D006801:Humans; D012038:Regeneration; D012627:Sebaceous Glands / Q000166:cytology; D012867:Skin / Q000166:cytology; D013234:Stem Cells / Q000166:cytology*; D023822:Tissue Engineering / Q000379:methods*