'Go with the flow ': a review of methods and advancements in blood flow imaging.
Physics has delivered extraordinary developments in almost every facet of modern life. From the humble thermometer and stethoscope to X-Ray, CT, MRI, ultrasound, PET and radiotherapy, our health has been transformed by these advances yielding both morphological and functional metrics. Recently high resolution label-free imaging of the microcirculation at clinically relevant depths has become available in the research domain. In this paper, we present a comprehensive review on current imaging techniques, state-of-the-art advancements and applications, and general perspectives on the prospects for these modalities in the clinical realm.
Biophotonics Research Facility, Department of Physics & Energy, University of Limerick, Ireland. susan.mcelligott@ul.ie
Susan M
SM
Daly
Martin J
MJ
Leahy
D000818:Animals; D001775:Blood Circulation; D018056:Hemorheology / Q000502:physiology; D006801:Humans; D057054:Molecular Imaging / Q000295:instrumentation / Q000379:methods*; D055096:Optical Devices