Evaluation of a hydrophilic ionic liquid as a salting-out phase separation agent to a water-tetrahydrofuran homogeneous system for aqueous biphasic extraction separation.
The use of a hydrophilic ionic liquid (IL), 1-butyl-3-methylimidazolium chloride (C(4)mimCl), as a salting-out phase separation agent to a water-tetrahydrofuran homogeneous system was studied for possible applications to novel aqueous biphasic extraction separation. The IL showed a salting-out phase-separation ability. Also, differences in the polarity between the formed two phases were smaller than that when using NaCl as a salting-out agent. This result suggested that C(4)mimCl remaining in water-rich phase acts not only as a salting-out agent, but also a component of a mixed-solvent. Possible uses of C(4)mimCl/NaCl mixed salting-out agent system were also discussed.
Department of Chemistry, Faculty of Science, Toho University, Funabashi, Japan. hirayama@sci.toho-u.ac.jp
Naoki
N
Hirayama
Takaaki
T
Higo
Hisanori
H
Imura
D005591:Chemical Fractionation / Q000379:methods*; D005590:Fractional Precipitation; D005663:Furans / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D007093:Imidazoles / Q000737:chemistry*; D052578:Ionic Liquids / Q000737:chemistry*; D012965:Sodium Chloride / Q000737:chemistry*; D013944:Thymolphthalein / Q000031:analogs & derivatives / Q000737:chemistry; D014867:Water / Q000737:chemistry*
D005663:Furans; D007093:Imidazoles; D052578:Ionic Liquids; D014867:Water; C018674:tetrahydrofuran; C502841:1-butyl-3-methylimidazolium chloride; D012965:Sodium Chloride; C013713:thymol blue; D013944:Thymolphthalein