Nuclear positioning: dynein needed for microtubule shrinkage-coupled movement.
Nuclear movement often requires interactions between the cell cortex and microtubules. A new study has revealed a novel protein interaction linking microtubule plus-ends with the cortex and a role for dynein in microtubule shrinkage-coupled movement.
Department of Biochemistry and Molecular Biology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA. Xin.Xiang@usuhs.edu
Xin
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Xiang
D018797:Cell Cycle Proteins / Q000378:metabolism*; D016547:Kinesins / Q000378:metabolism*; D008840:Microfilament Proteins / Q000378:metabolism*; D008868:Microtubule Proteins / Q000378:metabolism*; D008870:Microtubules / Q000502:physiology*; D008958:Models, Molecular; D012441:Saccharomyces cerevisiae / Q000254:growth & development*; D029701:Saccharomyces cerevisiae Proteins / Q000378:metabolism*; D008941:Spindle Apparatus / Q000502:physiology*
C119683:BIM1 protein, S cerevisiae; C107727:BUD6 protein, S cerevisiae; D018797:Cell Cycle Proteins; C108256:KIP3 protein, S cerevisiae; D008840:Microfilament Proteins; D008868:Microtubule Proteins; D029701:Saccharomyces cerevisiae Proteins; D016547:Kinesins