[Regulation of receptors coupled to G proteins (GPCRs)].
Regulation of G protein coupled receptors (GPCRs) looks to be not only classically lineary regulated but it is now discovered to be a complex network of interconnected proteins. Taking these in mind it is highly probable that there is multilevel system of regulation that is able to maintain control of signaling. We review here main mechanisms of GPCRs regulation.
Technická univerzita Liberec, Ustav zdravotnických studí Laborator fyziologie, Ceská republika.
H
H
Tománková
J
J
Myslivecek
D019393:Arrestin / Q000502:physiology; D006801:Humans; D010766:Phosphorylation; D011494:Protein Kinases / Q000502:physiology; D020710:RGS Proteins / Q000502:physiology; D043562:Receptors, G-Protein-Coupled / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology
D019393:Arrestin; D020710:RGS Proteins; D043562:Receptors, G-Protein-Coupled; D011494:Protein Kinases