Ganglioneuroma in a child with hereditary spherocytosis.
Hereditary spherocytosis (HS) is the most frequent cause of congenital hemolytic anemia. Extramedullary hematopoiesis (EMH) mimicking a mass may develop in the lymph nodes, kidneys, pleura, mediastinum, adrenal gland, and in particular the spleen and liver. Other than EMH, B-cell lymphoma, acute lymphoblastic leukemia, and pancreatic schwannoma cases were reported in patients with HS. We present a 13-year-old female patient with HS and ganglioneuroma in the adrenal gland. This association is probably coincidental; however, with increasing cancer cases in HS and the genetic studies being made, this association will be clarified.
Divisions of Pediatric Oncology, Ankara Children's Hematology Oncology Training and Research Hospital, Ankara, Turkey.
Haci Ahmet
HA
Demir
Semanur
S
Ozdel
Ayper
A
Kaçar
Emrah
E
Senel
Suna
S
Emir
Bahattin
B
Tunç
D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000601:surgery; D005260:Female; D005729:Ganglioneuroma / Q000150:complications* / Q000601:surgery; D006801:Humans; D013103:Spherocytosis, Hereditary / Q000150:complications*