[Overview of studies on detoxification effect of smilacis glabrae rhizoma on mercury poisoning].
Mercury-containing preparations are widely used in surgery department of traditional Chinese medicine and have made remarkable achievements. But they are toxic to human kidney, nerve, immune, etc. Smilacis Glabrae Rhizoma is sweet, tasteless and neutral in nature and able to enter liver and stomach channels and detoxify mercury poisoning. This article summarizes the mercury poisoning and the detoxification effect of Smilacis Glabrae Rhizoma in ancient records, pharmaceutical studies and clinical application, in order to provide ideas and methods for the safe use of mercury-containing preparations in surgery department of traditional Chinese medicine.
Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.
Xiaofei
X
Xu
Hongfeng
H
Chen
Meina
M
Ye
D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005753:Gastric Mucosa / Q000378:metabolism; D006801:Humans; D008658:Inactivation, Metabolic; D019668:Liliaceae / Q000737:chemistry*; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008516:Medicine, Chinese Traditional; D017669:Mercury Compounds / Q000009:adverse effects / Q000493:pharmacokinetics* / Q000627:therapeutic use; D008630:Mercury Poisoning / Q000517:prevention & control*; D010946:Plants, Medicinal / Q000737:chemistry*; D027343:Rhizome / Q000737:chemistry; D013270:Stomach / Q000187:drug effects
D004365:Drugs, Chinese Herbal; D017669:Mercury Compounds