Zonisamide-induced psychosis in a patient with bipolar disorder and narcolepsy.
Zonisamide is an anticonvulsant used as an adjunctive treatment for partial seizures. It has also been used off-label for treatment of mania. Abdoh et al recently reported a very interesting case of psychosis induced by zonisamide. We too observed a case of psychosis induced by zonisamide in a 34-year-old female with bipolar disorder and narcolepsy.
1Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, Piscataway, NJ; 2Department of Psychiatry, Columbia University Medical Center, New York, NY; and 3Platt Psychiatric Associates, Cedar Grove, NJ.
Jennifer E
JE
Platt
Lewis A
LA
Opler
Ellen M
EM
Platt
D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy; D005260:Female; D006801:Humans; D007555:Isoxazoles / Q000009:adverse effects* / Q000627:therapeutic use; D009290:Narcolepsy / Q000188:drug therapy; D011605:Psychoses, Substance-Induced / Q000209:etiology*; D000078305:Zonisamide
D000927:Anticonvulsants; D007555:Isoxazoles; D000078305:Zonisamide