Intravitreal bevacizumab for choroidal metastasis of lung carcinoma; a case report.
OBJECTIVE
To report an alternative treatment for metastatic tumors within the eye.


METHODS
Five intravitreal injections of bevacizumab (2.5 mg each) were performed in one eye of a 50-year-old woman with choroidal metastasis of lung carcinoma. Tumor size was reduced, pain disappeared, vision improved, and there were no secondary reactions. Vision improved from 20/40 to 20/20 and metamorphopsia decreased. Ten months after initiating treatment, an ultrasonographic study revealed no residual tumor, the choroid was normal in thickness and fluorescein angiography revealed a scar but no mass lesion.


CONCLUSIONS
Intravitreal bevacizumab displayed beneficial effects in reducing tumor size and improving symptoms in this case of choroidal metastasis of lung carcinoma. The antineoplasic properties of this agent make it a viable alternative for treatment of metastatic choroidal tumors.
Instituto Oftalmológico Hospital Conde de Valenciana, México City, Mexico.
Aída Sánchez
AS
de la Barquera Cordero
Rene Alfredo Cano
RA
Hidalgo