Pramipexole-related chronic lower limb oedema in a patient with Parkinson's disease.
Pramipexole is a non-ergot dopamine agonist that is used frequently as a single therapy or in combination for the management of Parkinson's disease. Common side effects are daytime drowsiness, hypotension, hallucinations and compulsive behaviour. We describe a patient who developed severe chronic and extensive lymphoedema after pramipexole was introduced and that resolved after its cessation.
Department of Neurology, Austin Health, 6 North, Austin Tower, 145 Studley Road, Heidelberg, Victoria 3084, Australia. zavala.md@gmail.com
Jorge A
JA
Zavala
Renato P
RP
Munhoz
Hélio A G
HA
Teive
D000842:Ankle / Q000473:pathology; D000978:Antiparkinson Agents / Q000009:adverse effects*; D001545:Benserazide / Q000627:therapeutic use; D052160:Benzothiazoles / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D004487:Edema / Q000150:complications* / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D035002:Lower Extremity / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000473:pathology; D000077487:Pramipexole; D012642:Selegiline / Q000627:therapeutic use
D000978:Antiparkinson Agents; D052160:Benzothiazoles; D012642:Selegiline; D007980:Levodopa; D001545:Benserazide; D000077487:Pramipexole