[The correction of lipid metabolism and microcirculation disturbances in early atherogenesis stages by thyroxine].
Thyroxine (T4) inhibits the development of lipid metabolism disorders and experimental atherosclerosis in rabbits (model N.N. Anichkov). The study of the hypothalamic-pituitary system, thyroid, and the microvascular bed also revealed a beneficial effect of thyroxine on their morpho-functional state. Thus, the role of neuroendocrine regulation and disorders of microcirculation in atherogenesis shown.
L P
LP
Kobozeva
E D
ED
Klimenko
A B
AB
Michunskaia
O M
OM
Pozdniakov
D000818:Animals; D050197:Atherosclerosis / Q000188:drug therapy* / Q000378:metabolism; D004195:Disease Models, Animal; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism*; D050356:Lipid Metabolism / Q000187:drug effects*; D008297:Male; D008833:Microcirculation / Q000187:drug effects*; D011817:Rabbits; D013974:Thyroxine / Q000494:pharmacology*
D013974:Thyroxine