A molecular bandage for diseased muscle.
MG53 promotes sarcolemmal repair in the mdx mouse model of Duchenne muscular dystrophy (Weisleder et al., this issue) and identifies a new protein therapeutic for muscle disease.
Department of Pharmacology, Center for Molecular Medicine, University of Nevada School of Medicine, Reno, NV 89557, USA. dburkin@medicine.nevada.edu
Dean J
DJ
Burkin
Ryan D
RD
Wuebbles
D000818:Animals; D002352:Carrier Proteins / Q000627:therapeutic use*; D002462:Cell Membrane / Q000187:drug effects* / Q000378:metabolism*; D006801:Humans; D008297:Male; D009136:Muscular Dystrophies / Q000188:drug therapy* / Q000378:metabolism*; D000070584:Tripartite Motif Proteins
D002352:Carrier Proteins; C558399:TRIM72 protein, human; D000070584:Tripartite Motif Proteins