Effectiveness of magnesium citrate as preparation for capsule endoscopy: a randomized, prospective, open-label, inter-group trial.
OBJECTIVE
Capsule endoscopy (CE) is effective in the detection of small bowel lesions. Many studies have been conducted on the effectiveness of preparations in improving diagnostic yield, but an effective method has yet to be confirmed. We used magnesium citrate as preparation for CE and evaluated its effectiveness.


METHODS
50 patients who underwent CE were randomly allocated to two groups - group A (preparation provided) and group B (no preparation). Group A were administered 34 g of magnesium citrate at 8 p.m. the night before the examination. Group B were not administered a laxative.


RESULTS
The cleansing efficacy score was 24.4 ± 4.4 points for group A and 22.9 ± 4.4 points for group B, with no significant difference between groups. No significant difference was seen in the large bowel arrival rate between groups: 14 cases (63.6%) for group A and 16 cases (72.7%) for group B.


CONCLUSIONS
In this study, superiority was not seen for cleansing efficacy, large bowel arrival rate for the preparation method involving administration of hypertonic MC solution 12 h prior to the procedure.
Department of Gastroenterology, Fukuoka University Chikushi Hospital, Chikushino City, Japan.
Kazeo
K
Ninomiya
Kenshi
K
Yao
Toshiyuki
T
Matsui
Yuho
Y
Sato
Masahiro
M
Kishi
Yoshihiko
Y
Karashima
Hiroshi
H
Ishihara
Fumihito
F
Hirai
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D053704:Capsule Endoscopy / Q000379:methods* / Q000592:standards; D002400:Cathartics / Q000008:administration & dosage*; D016009:Chi-Square Distribution; D019343:Citric Acid / Q000008:administration & dosage*; D005260:Female; D005772:Gastrointestinal Transit; D006801:Humans; D007421:Intestine, Small / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds / Q000008:administration & dosage*; D018709:Statistics, Nonparametric
D002400:Cathartics; D009942:Organometallic Compounds; D019343:Citric Acid; C110422:magnesium citrate