Copper(I)-catalyzed cascade sulfonimidate to sulfonamide rearrangement: synthesis of imidazo[1,2-a][1,4]diazepin-7(6H)-one.
A novel strategy of copper(I)-catalyzed cascade intramolecular nucleophilic attack on N-sulfonylketenimine followed by rearrangement of sulfonimidates to sulfonamides resulting in a library of substituted 8,9-dihydro-5H-imidazo[1,2-a][1,4]diazepin-7(6H)-ones has been developed.
Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625 021, India.
Muthupandi
M
Nagaraj
Muthusamy
M
Boominathan
Devanathan
D
Perumal
Shanmugam
S
Muthusubramanian
Nattamai
N
Bhuvanesh
D001381:Azepines / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D007093:Imidazoles / Q000737:chemistry*; D015394:Molecular Structure; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000737:chemistry
D001381:Azepines; D007093:Imidazoles; D013449:Sulfonamides; C576326:imidazo(1,2-a)(1,4)diazepin-76H-one; D003300:Copper