SEOM clinical guidelines for the management of adult soft tissue sarcomas.
Soft tissue sarcomas are uncommon tumors of mesenchimal cell origin. Criteria for suspicion is a soft tissue mass that is increasing in size, and has a size greater than 5 cm or is located under the deep fascia. Diagnosis and management of these patients should preferably be performed by a specialist multidisciplinary team in a referral center. Assessment of a patient with a suspect of sarcoma should include magnetic resonance and biopsy performed prior to surgery. Primary local therapy for patients with localized sarcoma is based on wide surgical resection with a tumor-free tissue margin, in association in most cases with radiotherapy. Adjuvant chemotherapy constitutes an option that could be considered in high-risk sarcomas of the extremities. When metastasis are present, surgery of pulmonary lesions, in some selected patients, and chemotherapy are current available options.
Department of Medical Oncology, Institut Català d'Oncologia L'Hospitalet, Hospital Duran i Reynals, L'Hospitalet de Llobregat, Barcelona, Spain. garciadelmuro@iconcologia.net
Xavier
X
García del Muro Solans
Javier
J
Martín Broto
Pilar
P
Lianes Barragán
Ricardo
R
Cubedo Cervera
D000328:Adult; D000465:Algorithms; D003663:Decision Trees; D006801:Humans; D008495:Medical Oncology / Q000331:legislation & jurisprudence; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging / Q000379:methods; D012509:Sarcoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D013030:Spain