Evaluation and establishment of a canine model of delayed splenic rupture             using contrast-enhanced ultrasound.
The aim of the present study was to establish a canine model of delayed             splenic rupture (DSR). A total of 15 mongrel dogs were anesthetized and laparotomized.             The hematomas were observed following an injection of heparin. The hematomas were             ruptured. The severity of the spleen rupture was evaluated and the intra-abdominal             free liquid was measured. The splenic hematomas in the dogs continued to form             and the hematoma area gradually increased. The hematomas were ruptured after impacting             the abdominal wall. The spleens were damaged, and conventional ultrasonography             showed intra-abdominal free liquid. These conditions were demonstrated via computed             tomography scanning. A DSR canine model was established successfully.
Department of Ultrasound, Chinese People's Liberation Army General Hospital, Beijing 100853, PR China.
Jiangke
J
Tian
Xia
X
Xie
Faqin
F
Lv
Tengfei
T
Yu
Rong
R
Wu
Xinghua
X
Zhang
Dong
D
Wang
Jie
J
Tang
D000818:Animals; D003287:Contrast Media; D004195:Disease Models, Animal; D004285:Dogs; D006406:Hematoma / Q000000981:diagnostic imaging* / Q000209:etiology / Q000662:veterinary; D006493:Heparin / Q000008:administration & dosage; D013158:Splenic Diseases / Q000000981:diagnostic imaging* / Q000662:veterinary; D013161:Splenic Rupture / Q000150:complications* / Q000662:veterinary; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
D003287:Contrast Media; D006493:Heparin