Promising therapies for treating and/or preventing androgenic alopecia.
Androgenetic alopecia (AGA) may affect up to 70% of men and 40% of women at some point in their lifetime. While men typically present with a distinctive alopecia pattern involving hairline recession and vertex balding, women normally exhibit a diffuse hair thinning over the top of their scalps. The treatment standard in dermatology clinics continues to be minoxidil and finasteride with hair transplantation as a surgical option. Here we briefly review current therapeutic options and treatments under active investigation. Dutasteride and ketoconazole are also employed for AGA, while prostaglandin analogues latanoprost and bimatoprost are being investigated for their hair growth promoting potential. Laser treatment products available for home use and from cosmetic clinics are becoming popular. In the future, new cell mediated treatment approaches may be available for AGA. While there are a number of potential treatment options, good clinical trial data proving hair growth efficacy is limited.
Department of Dermatology and Skin Science, The University of British Columbia, Vancouver, BC, Canada.
K J
KJ
McElwee
J S
JS
Shapiro
D000505:Alopecia / Q000188:drug therapy / Q000517:prevention & control / Q000628:therapy*; D005260:Female; D018120:Finasteride / Q000627:therapeutic use; D006197:Hair / Q000254:growth & development* / Q000637:transplantation; D006801:Humans; D053685:Laser Therapy / Q000379:methods; D008297:Male; D008914:Minoxidil / Q000627:therapeutic use; D012737:Sex Factors
D018120:Finasteride; D008914:Minoxidil