Frequency and etiology of unexplained bilateral hydronephrosis in patients with breast cancer: results of a longitudinal CT study.
We retrospectively reviewed the records of 153 patients with breast cancer undergoing serial abdominal computed tomography (CT). During a median follow-up of 40 months, 2 (1.4%) of 153 patients developed bilateral hydronephrosis in the absence of radiologically visible obstructing pathology. Surgery confirmed malignant infiltration of the ureters by metastatic lobular carcinoma in both patients, suggesting that new unexplained bilateral hydronephrosis on serial CT in patients with breast cancer is likely to reflect infiltrative retroperitoneal involvement of the ureters by metastatic lobular carcinoma.
Department of Radiology, University of California San Francisco, San Francisco, CA 94143-0628, USA.
Ari J
AJ
Kane
Zhen J
ZJ
Wang
Aliya
A
Qayyum
Benjamin M
BM
Yeh
Emily M
EM
Webb
Fergus V
FV
Coakley
D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D018275:Carcinoma, Lobular / Q000401:mortality / Q000556:secondary* / Q000628:therapy; D016208:Databases, Factual; D005260:Female; D006801:Humans; D006869:Hydronephrosis / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000209:etiology*; D015994:Incidence; D008137:Longitudinal Studies; D008875:Middle Aged; D011379:Prognosis; D011857:Radiographic Image Interpretation, Computer-Assisted; D012186:Retroperitoneal Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000556:secondary*; D012189:Retrospective Studies; D018570:Risk Assessment; D016019:Survival Analysis; D014057:Tomography, X-Ray Computed / Q000379:methods