Sanjecumins A and B: new limonoids from Sandoricum koetjape.
Two new limonoids, sanjecumins A (1) and B (2), have been isolated from the leaves of Sandoricum koetjape, together with sandoripins A (3) and B (4). Their structures and absolute configurations were elucidated on the basis of NMR and CD data. Sandoripins A (3) and B (4) moderately inhibited nitric oxide production in mouse macrophage-like cell line J774.1 stimulated by lipopolysaccharide.
Hoshi University, 2-4-41 Ebara, Shinagawa-ku, Tokyo, 142-8501, Japan.
Yuta
Y
Nagakura
Alfarius Eko
AE
Nugroho
Yusuke
Y
Hirasawa
Takahiro
T
Hosoya
Abdul
A
Rahman
Idha
I
Kusumawati
Noor Cholies
NC
Zaini
Hiroshi
H
Morita
D000818:Animals; D002460:Cell Line; D036701:Limonins / Q000737:chemistry* / Q000494:pharmacology*; D008070:Lipopolysaccharides / Q000494:pharmacology; D008264:Macrophages / Q000187:drug effects / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D029582:Meliaceae / Q000737:chemistry*; D051379:Mice; D015394:Molecular Structure; D009569:Nitric Oxide / Q000378:metabolism; D018515:Plant Leaves / Q000737:chemistry
D036701:Limonins; D008070:Lipopolysaccharides; D009569:Nitric Oxide