[Early resorptive effects of highly toxic alkylating substances].
In the next few hours after exposure of mustards in harmful doses the injured suffer a complex of neurological deficits-headache, asthenia and emetic syndrome, and in case of lethal dosage-adynamia, tremor and convulsions. In case of percutaneous exposure of sulfur mustard, these disorders limit the terms of the conservation capacity of injured and determine the nature of the medical care they need at the pre-hospital stage. Perspective areas of drug prevention and treatment of early manifestations of acute resorptive action of mustards are the use of antiemetics, analgesics, and the removal of endogenous toxemia caused by inflammatory mediators, and biologically active substances in the gastro-intestinal origin.
Iu Iu
IuIu
Ivnitskiĭ
V L
VL
Reĭniuk
T V
TV
Shefer
D000818:Animals; D000931:Antidotes / Q000627:therapeutic use*; D001247:Asthenia / Q000139:chemically induced / Q000517:prevention & control; D002619:Chemical Warfare Agents / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D006261:Headache / Q000139:chemically induced / Q000517:prevention & control; D006801:Humans; D009151:Mustard Gas / Q000009:adverse effects*; D011041:Poisoning / Q000517:prevention & control*; D012640:Seizures / Q000139:chemically induced / Q000517:prevention & control; D014202:Tremor / Q000139:chemically induced / Q000517:prevention & control; D014839:Vomiting / Q000139:chemically induced / Q000517:prevention & control
D000931:Antidotes; D002619:Chemical Warfare Agents; D009151:Mustard Gas