C-H activation in S-alkenyl sulfoximines: an endo 1,5-hydrogen migration.
Intramolecular redox reaction: heating N-alkyl, N-allyl-, and N-benzyl-substituted S-alkenyl sulfoximines under appropriate conditions results in the formation of NH-S-alkyl sulfoximines. The intramolecular redox reaction involves a hydride transfer that occurs by a 6-endo-trig process. The intermediates in the reaction can also give access to four- and six-membered heterocyclic rings and a new class of chiral dienes.
Department of Chemistry, University of Missouri-Columbia, 65211, USA.
Xuefeng
X
Gao
Vikram
V
Gaddam
Erich
E
Altenhofer
Rama Rao
RR
Tata
Zhengxin
Z
Cai
Nattawut
N
Yongpruksa
Aswin K
AK
Garimallaprabhakaran
Michael
M
Harmata