Seborrheic dermatitis: an update.
Seborrheic dermatitis is a chronic relapsing inflammatory skin disorder clinically characterized by scaling and poorly defined erythematous patches. The prevalence of adult seborrheic dermatitis is estimated at 5%. Although the exact cause of seborrheic dermatitis has yet to be understood, Malassezia yeasts, hormones (androgens), sebum levels and immune response are known to play important roles in its development. Additional factors including drugs, winter temperatures and stress may exacerbate seborrheic dermatitis. A variety of treatment modalities are available, including antifungal agents, topical low-potency steroids and calcineurin inhibitors (immunomodulators). This review summarizes current knowledge on the etiopathogenesis and therapy of adult seborrheic dermatitis.
University Hospital Center Zagreb, Department of Dermatology and Venereology, School of Medicine University of Zagreb, Šalata 4, HR-10000 Zagreb, Croatia. zrinka.bukvic@zg.t-com.hr
Zrinka
Z
Bukvić Mokos
Martina
M
Kralj
Aleksandra
A
Basta-Juzbašić
Ines
I
Lakoš Jukić
D000935:Antifungal Agents / Q000627:therapeutic use; D065095:Calcineurin Inhibitors; D015897:Comorbidity; D012628:Dermatitis, Seborrheic / Q000175:diagnosis / Q000209:etiology / Q000378:metabolism / Q000382:microbiology / Q000628:therapy*; D003881:Dermatomycoses; D003937:Diagnosis, Differential; D006801:Humans; D008290:Malassezia; D010300:Parkinson Disease / Q000453:epidemiology; D010789:Phototherapy; D012629:Sebum / Q000378:metabolism
D000935:Antifungal Agents; D065095:Calcineurin Inhibitors