The immunohistochemistry aspects in two cases of neurofibromatosis-associated abdominal tumors.
Type 1 neurofibromatosis associates various abdominal tumors as gastrointestinal stromal tumors, duodenal or pancreatic carcinoid, and adrenal tumors like pheochromocytoma. We present the immunohistochemistry report in two cases with different profile regarding the evolution. One case is a 7th decade women diagnosed with unilateral pheochromocytoma and GISTs, with a good prognosis after surgery. The other case is a 41-year-old male diagnosed with duodenal metastatic somatostatinoma after an intestinal occlusive syndrome and later the hormonal profile leaded to the diagnosis of pheochromocytoma. The patient had a fulminate evolution within six months from diagnosis.
Carol Davila University of Medicine and Pharmacy, Bucharest. drcristianneamtu@yahoo.com
Mara
M
Carşote
S
S
Păun
M C
MC
Neamţu
Elena Taina
ET
Avramescu
Cristina
C
Iosif
Dana
D
Terzea
S
S
Constantinoiu
Ruxandra
R
Dănciulescu Miulescu
Oana Maria
OM
Neamţu
Cătălina
C
Poiană
D000008:Abdominal Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology*; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology*; D000328:Adult; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology*; D010673:Pheochromocytoma / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology*; D013005:Somatostatinoma / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology*