Light-triggered charge reversal of organic-silica hybrid nanoparticles.
A functional nanoparticle with light-triggered charge reversal based on a protected amine-bridged polysilsesquioxane was designed. An emulsion- and amine-free sol-gel synthesis was developed to prepare uniform nanospheres. Photolysis of suspensions of these nanoparticles results in a reversal of the ζ potential. This behavior has been used to trigger nanoparticle self-assembly, nanocomposite hydrogel formation, and nanoparticle release, showing the potential of this material in nanoscale manipulation and nanoparticle therapy.
Department of Chemistry, University of California, Irvine, California 92697, USA.
Li-Chih
LC
Hu
Yusuke
Y
Yonamine
Shih-Hui
SH
Lee
Wytze E
WE
van der Veer
Kenneth J
KJ
Shea