Proteomic updates on sepsis.
The increased knowledge regarding proteomic analysis techniques has allowed for better understanding of the molecular bases related to the identification of cell signaling, modifying protein, and post-translational modification pathways, in addition to the characterization of specific biological markers. Thus, documenting certain proteins expressed in sepsis is a promising approach to elucidate pathophysiological, diagnostic, therapeutic, and prognostic aspects in this condition with a purpose of applying them to clinical practice. Although the studies are still preliminary, proteomics may offer good benefits for the better management of septic patients. Thus, this article aims to introduce a short review of the applications of proteomic studies to sepsis.
Department of Medicine and Nursing and at the Department of Biochemistry and Molecular Biology, Universidade Federal de Viçosa (UFV), Viçosa, MG, Brazil. rsbatista@ufv.br
Rodrigo
R
Siqueira-Batista
Eduardo Gomes de
EG
Mendonça
Andréia Patrícia
AP
Gomes
Rodrigo Roger
RR
Vitorino
Renato
R
Miyadahira
Mario Castro
MC
Alvarez-Perez
Maria Goreti de Almeida
MG
Oliveira
D015415:Biomarkers / Q000378:metabolism; D006801:Humans; D011379:Prognosis; D040901:Proteomics / Q000379:methods*; D018805:Sepsis / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism
D015415:Biomarkers