ortho-Quinone methides in natural product synthesis.
ortho-Quinone methides (o-QMs) are emerging as highly useful intermediates, the inherent reactivity of which can be used in linchpin reactions for the construction of complex natural products. This review encompasses the major contributions in this field, exemplifying the major strategies and reactivity modes which can be applied.
School of Biological and Chemical Science, Queen Mary University of London, Mile End Road, London, E1 4NS, UK.
Nicky J
NJ
Willis
Christopher D
CD
Bray
D001578:Benzopyrans / Q000737:chemistry*; D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry*; D003500:Cyclization; D045563:Indolequinones / Q000138:chemical synthesis* / Q000737:chemistry*; D013329:Structure-Activity Relationship
D001578:Benzopyrans; D001688:Biological Products; D045563:Indolequinones; C068040:quinone methide