[Immunohistochemical study of adhesive molecules Her-2/neu in nonendometrial carcinoma of corpus uteri].
46 cases of nonendometrial carcinoma of the corpus uteri have been studied. The expressions of E-cadherin, alpha and beta-catenins were detected by immunohistochemical method. The high level of studied markers expression was founded out in clear cell carcinoma, whereas the less expression was detected in the corpus uteri of patients with serous, papillary, undifferentiated and mixed cancer. The absence of E-cadherin, alpha and beta-catenins complex expression correlated with unfavorable clinic-morphological features of carcinoma.
G M
GM
abdulaeva
O A
OA
Anurova
K P
KP
Laktionov
S M
SM
Gadzhieva
D015815:Cell Adhesion Molecules / Q000096:biosynthesis*; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D007150:Immunohistochemistry; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000096:biosynthesis*; D018227:Sarcoma, Clear Cell / Q000378:metabolism* / Q000473:pathology*; D014594:Uterine Neoplasms / Q000378:metabolism* / Q000473:pathology*
D015815:Cell Adhesion Molecules; D018719:Erb-b2 Receptor Tyrosine Kinases; C508053:ERBB2 protein, human