Persistence of placenta previa in twin gestations based on gestational age at sonographic detection.
OBJECTIVE
The purpose of this study was to evaluate the gestational age at sonographic detection of placenta previa as a predictor of previa persistence until delivery in twin gestations.


METHODS
A retrospective cohort of twin pregnancies with placenta previa in a single ultrasound unit was analyzed from 2005 to 2010. Pregnancies were ascertained from a database. Diagnoses were confirmed by transvaginal imaging. Previa was categorized as complete if the placenta completely covered the internal os or marginal if the inferior placental edge reached within 2 cm. Gestational ages were grouped into intervals from 15 to 35 weeks. The study outcome was placenta previa at delivery. Only twin pregnancies at 25 weeks' gestation and later were analyzed using nonparametric statistics as appropriate, with P < .05 as significant.


RESULTS
Placenta previa was detected in 120 twin pregnancies in the second trimester: 32 complete and 88 marginal. Of those with placenta previa at 15 to 19, 20 to 23, 24 to 27, 28 to 31, and 32 to 35 weeks, previa persisted until delivery in 8.3%, 19.2%, 50%, 75%, and 92.5%, respectively. Only at 15- to 19- and 20- to 23-week intervals was complete previa more likely to persist than marginal previa (P < .001).


CONCLUSIONS
The likelihood of placenta previa persistence in twins is dependent on the gestational age at sonographic detection. Only at earlier gestations does the type of previa affect its persistence. As gestational age advances, the likelihood of resolution of placenta previa diminishes regardless of the type noted.
Mount Sinai School of Medicine, 5 E 98th St, Second Floor, New York, NY 10029-6574, USA. katherine.kohari@mssm.edu
Katherine S
KS
Kohari
Ashley S
AS
Roman
Nathan S
NS
Fox
Jessica
J
Feinberg
Daniel H
DH
Saltzman
Chad K
CK
Klauser
Andrei
A
Rebarber
D005260:Female; D005865:Gestational Age; D006801:Humans; D010923:Placenta Previa / Q000000981:diagnostic imaging*; D011247:Pregnancy; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014427:Twins; D016216:Ultrasonography, Prenatal / Q000379:methods*