[Metabolism-related risk factors of cholelithiasis among Beijing residents: a case-control study].
OBJECTIVE
To explore the metabolism-related risk factors of cholelithiasis among residents in Beijing.


METHODS
The clinical data including previous disease history, findings of physical examination, and results of cholecystosonography of 2270 patients with cholelithiasis identified in the Health Screening Center of Peking Union Medical College Hospital between August 2007 and August 2010 were retrospectively reviewed (the case group). Meanwhile, 4336 healthy individuals during the same period were randomly chosen as the control group.


RESULTS
Total cholesterol, triglyceride, low-density lipoprotein cholesterol, fasting blood glucose, body mass index, and systolic blood pressure were positively correlated with the incidence of cholelithiasis (P < 0.05), while high-density lipoprotein cholesterol was negatively correlated (P < 0.05). Diastolic blood pressure showed no association with cholelithiasis (P > 0.05).


CONCLUSIONS
Cholelithiasis is resulted from multiple factors including elevated blood lipids, blood glucose, and systolic blood pressure among residents in Beijing.
Department of General Surgery, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Ying-Chao
YC
Gu
Xiao-Dong
XD
He
Jian-Chun
JC
Yu
Wei-Ming
WM
Kang
Lian-Yuan
LY
Tao
Qiao
Q
Wu
D000328:Adult; D000368:Aged; D001786:Blood Glucose; D001794:Blood Pressure; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D002769:Cholelithiasis / Q000453:epidemiology* / Q000378:metabolism; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
D001786:Blood Glucose; D008055:Lipids