[Rare blood group screening by serological and molecular methods in Zhejiang Han population].
This study was aimed to investigate the distribution of rare blood group in Zhejiang Han population. The H(-) (H system), GPA(-) and s(-) (MNS), Rhnull, Rhmod, D--, CCDEE, CCdEE (variations of Rh), GPC(-) (Gerbich), i(+) (I), Lu(b-) (Lutheran), Js(b-) and k(-) (Kell), Fy(a-) (Duffy), Ok(a-) (Ok), Di(b-) (Diego) phenotypes were screened by serological or molecular methods. Jk (a-b-) phenotype was detected by urea hemolytic test. The results showed that one Di (a+b-) individual was found in 1618 blood donors, three Fy (a-b+) individuals in 1007 donors and one CCdEE individual in 633 Rh negative donors. No Jk (a-b-), H(-), GPA(-), s(-), GPC(-), i(+) (adult), Lu(b-), k(-), Js(b-), Lu(b-) and Ok(a-) phenotypes were found in this large scale survey. It is concluded that Di (a+b-), Fy (a-b+), CCdEE phenotypes are confirmed in the blood donors and this study provides the distribution data of erythrocyte rare blood group in Zhejiang Han population.
Blood Center of Zhejiang Province, Hangzhou, Zhejiang Province, China.
Hong
H
Zhu
Ying
Y
Liu
Xiao-Zhen
XZ
Hong
Xiao-Guo
XG
Xu
Xiao-Fei
XF
Lan
Kai-Rong
KR
Ma
Ji
J
He
Fa-Ming
FM
Zhu
Hang-Jun
HJ
Lu
D044466:Asian People / Q000235:genetics; D001789:Blood Group Antigens / Q000235:genetics*; D001788:Blood Grouping and Crossmatching / Q000379:methods*; D004912:Erythrocytes / Q000276:immunology*; D006801:Humans; D008967:Molecular Biology; D010641:Phenotype
D001789:Blood Group Antigens