Anaphylaxis.
OBJECTIVE
This article aims to make a review of the up-to-date knowledge on anaphylaxis and outline the recent advances on pathophysiology, diagnosis, and management of anaphylaxis.


RESULTS
New data confirm the increase in prevalence of anaphylaxis and emphasize immunopathologic mechanisms. However, anaphylaxis is often underdiagnosed and guidelines are poorly applied, particularly in emergency departments.


CONCLUSIONS
An improvement of rapid diagnosis and treatment combined with education of population will decrease mortality and morbidity of anaphylaxis.
Emergency Department, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Marie-Bénédicte
MB
De Bisschop
Abdelouahab
A
Bellou
D000485:Allergens / Q000009:adverse effects* / Q000276:immunology; D000707:Anaphylaxis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D001993:Bronchodilator Agents / Q000627:therapeutic use; D004837:Epinephrine / Q000627:therapeutic use; D005602:France / Q000453:epidemiology; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D015994:Incidence; D015995:Prevalence; D012307:Risk Factors
D000485:Allergens; D001993:Bronchodilator Agents; D006634:Histamine H1 Antagonists; D004837:Epinephrine