Targeted therapy: a new approach for the treatment of locally advanced oropharyngeal cancer.
Presented herein is a clinical study comprising 48 patients (42 men and 6 women) of working age (40-70 years), all of whom are suffering from locally advanced oropharyngeal cancer. A modern approach is applied to treat these patients,i.e., neoadjuvant targeted therapy, taking into account the biological profile of the tumor. The use of gefitinib causes an antitumor effect in 90.5% of cases as opposed to 56.5% when no drug is applied.
Moscow State Medical and Dental University.
L Z
LZ
Velsher
A A
AA
Kosmynin
M Yu
MY
Byakhov
T K
TK
Duditskaya
D N
DN
Reshetov