Extracranial malignant germ cell tumors.
The outstanding clinical trials undertaken for the management of pediatric extracranial malignant germ cell tumors (GCTs) in the developed world in the last three decades has led to excellent longterm outcomes. The scenario in developing country like India is different; results are poor owing to multiple factors such as delayed presentation, misdiagnosis, and early abandonment of the therapy. The authors address here several aspects of this heterogeneous group of malignant tumors in children and adolescents such as the different staging systems, the risk stratification, the guidelines to treatment modalities, the outcome and prognostication.
Department of Pediatric Surgery, Maulana Azad Medical College, Bahadur Shah Zafar Marg, New Delhi 110002, India. yksarin@hotmail.com
Yogesh Kumar
YK
Sarin
Sushmita Nitin
SN
Bhatnagar
D000293:Adolescent; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000145:classification / Q000175:diagnosis / Q000628:therapy; D010051:Ovarian Neoplasms / Q000145:classification / Q000175:diagnosis / Q000628:therapy; D011379:Prognosis; D018570:Risk Assessment; D013736:Testicular Neoplasms / Q000145:classification / Q000175:diagnosis / Q000628:therapy