My legs are getting old: sinvastatin-induced polyneuropathy.
Axonal degeneration is the most common type of neuropathy induced by medication. The literature describes isolated cases in which polyneuropathy of the lower limb was observed during treatment with statins. The authors present a case of polyneuropathy associated with the use of a statin. An 82-year-old female patient presented with a complaint of weakness and discomfort in her lower limbs after 7 years of therapy with simvastatin. The results of an electromyographic study were compatible with polyneuropathy (sensorimotor axonal neuropathy--moderate to severe). One month after the therapy with simvastatin was discontinued, the symptoms were reduced.
Geriatric Medical Centre, University Hospital, Brasilia University, Brazil. einstein@unb.br
Einstein Francisco
EF
Camargos
Larissa de Freitas
Lde F
Oliveira
Thaís de Deus Vieira
Tde D
Boaventura
D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D000960:Hypolipidemic Agents / Q000009:adverse effects*; D007866:Leg / Q000294:innervation*; D011115:Polyneuropathies / Q000139:chemically induced*; D019821:Simvastatin / Q000009:adverse effects*
D000960:Hypolipidemic Agents; D019821:Simvastatin