Stereoselective construction of the tetracyclic core of Cryptotrione.
An efficient stereoselective approach to the tetracyclic core of Cryptotrione, involving an asymmetric Michael addition, ring-closing metathesis, and subsequent cyclopropanation, is described.
Beijing National Laboratory of Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Song
S
Chen
Chao
C
Rong
Pengju
P
Feng
Songlei
S
Li
Yian
Y
Shi
D002384:Catalysis; D003300:Copper / Q000737:chemistry; D003500:Cyclization; D003521:Cyclopropanes / Q000737:chemistry; D013237:Stereoisomerism; D013729:Terpenes / Q000737:chemistry*
D003521:Cyclopropanes; D013729:Terpenes; C551665:cryptotrione; D003300:Copper; C030797:cyclopropane