Characterization of bisphenol A metabolites produced by Portulaca oleracea cv. by liquid chromatography coupled with tandem mass spectrometry.
The garden plant portulaca (Portulaca oleracea cv.) efficiently removes bisphenol A (BPA), an endocrine-disrupting chemical, from a hydroponic solution, but the molecular mechanisms underlying BPA metabolism by portulaca remain unclear. In this study, BPA metabolites converted by portulaca were analyzed by liquid chromatography coupled with tandem mass spectrometry. We observed the hydroxylation of BPA and the oxidization of it to quinone. Polyphenol oxidases are likely to contribute to BPA degradation by portulaca.
Applied Environmental Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Suite, Japan.
Ippei
I
Watanabe
Kazuo
K
Harada
Takeshi
T
Matsui
Hitoshi
H
Miyasaka
Hiroshi
H
Okuhata
Satoshi
S
Tanaka
Hideki
H
Nakayama
Ko
K
Kato
Takeshi
T
Bamba
Kazumasa
K
Hirata
D000395:Air Pollutants, Occupational / Q000378:metabolism*; D001559:Benzhydryl Compounds; D001673:Biodegradation, Environmental; D004156:Catechol Oxidase / Q000378:metabolism; D002853:Chromatography, Liquid; D052244:Endocrine Disruptors / Q000378:metabolism*; D010636:Phenols / Q000378:metabolism*; D031822:Portulaca / Q000201:enzymology*; D011809:Quinones / Q000378:metabolism*; D053719:Tandem Mass Spectrometry; D000098826:Bisphenol A Compounds
D000395:Air Pollutants, Occupational; D001559:Benzhydryl Compounds; D004156:Catechol Oxidase; D052244:Endocrine Disruptors; D010636:Phenols; D011809:Quinones; C006780:bisphenol A; D000098826:Bisphenol A Compounds