Octreotide infusion for malignant duodenal obstruction in a 12-year-old girl with metastatic peripheral nerve sheath tumor.
Malignant bowel obstruction is a common complication of some adult malignancies. In childhood cancer, malignant bowel obstruction is relatively rare. Octreotide, an analogue of the hormone somatostatin, has been shown to be an effective treatment for this condition in adults. However, explicit description of its use for this indication in children was not discovered in the pediatric literature by this group of authors. The following report is that of a 12-year-old female who had copious bilious emesis secondary to malignant obstruction of the distal duodenum, which abated after treatment with a continuous intravenous octreotide infusion.
Stollery Children's Hospital, Edmonton, AB, Canada. dawn.davies@albertahealthservices.ca
Dawn E
DE
Davies
Tara
T
Wren
Shona M
SM
MacLachlan
D000008:Abdominal Neoplasms / Q000150:complications*; D002648:Child; D004380:Duodenal Obstruction / Q000188:drug therapy*; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D018317:Nerve Sheath Neoplasms / Q000150:complications* / Q000473:pathology; D015282:Octreotide / Q000627:therapeutic use*
D015282:Octreotide