[Advances in syphilis detection].
Syphilis, a chronic bacterial infection caused by the spirochete Treponema pallidum subsp. pallidum, remains a public health concern worldwide. Syphilis control is largely dependent upon early identification and prompt treatment. The diagnosis of syphilis is mainly based on laboratory tests, especially serology and dark-field microscopy. In recent years, recombinant Treponema pallidum antigen-based rapid tests, polymerase chain reaction, and immunoglobulin M antibody detection have also shown certain sensitivities and specificities for syphilitic patients at different stages.
Department of Dermatology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
Jun
J
Li
He-Yi
HY
Zheng
D000942:Antigens, Bacterial / Q000097:blood; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D016133:Polymerase Chain Reaction / Q000379:methods; D012680:Sensitivity and Specificity; D013587:Syphilis / Q000097:blood / Q000175:diagnosis*; D013588:Syphilis Serodiagnosis; D014210:Treponema pallidum / Q000276:immunology / Q000302:isolation & purification
D000942:Antigens, Bacterial; D007075:Immunoglobulin M