Bilateral inferior petrosal sinus sampling with desmopressin.
In this technical note, the use of desmopressin to stimulate pituitary adrenocorticotropic hormone secretion in place of the commercially available corticotropin releasing hormone (CRH) in bilateral inferior petrosal sinus sampling is described. Although the use of CRH is the standard of practice, it is currently unavailable in the USA and desmopressin provides reliable results with no additional observed side effects.
Department of Radiology, Division of Vascular Imaging and Intervention, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Amy R
AR
Deipolyi
Joshua A
JA
Hirsch
Rahmi
R
Oklu
D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D003346:Corticotropin-Releasing Hormone / Q000009:adverse effects; D003894:Deamino Arginine Vasopressin / Q000009:adverse effects; D006801:Humans; D017591:Petrosal Sinus Sampling / Q000009:adverse effects* / Q000379:methods*; D047748:Pituitary ACTH Hypersecretion / Q000175:diagnosis
D000324:Adrenocorticotropic Hormone; D003346:Corticotropin-Releasing Hormone; D003894:Deamino Arginine Vasopressin