Is total community viral load a robust predictive marker of the efficacy of the TasP strategy?
A mild but significant association between a decrease in the total community viral load (CVL) and a decrease in the number of new HIV diagnoses was observed between 2005 and 2010 in the population of northern and eastern France. This result suggests that CVL could be used as robust marker of the efficacy of the "Treatment as Prevention" strategy, and it may even be stronger if a large number of undiagnosed patients and early HIV infection cases indicated by extend screening are included in the CVL measurement.
Service des maladies infectieuses et tropicales, Centre Hospitalier Universitaire de Nancy, Nancy, France. sandrine.henard@wanadoo.fr
Sandrine
S
Henard
Eliette
E
Jeanmaire
Yohan
Y
Nguyen
Yazdan
Y
Yazdanpanah
Antoine
A
Cheret
Bruno
B
Hoen
David
D
Rey
Alice
A
Borel
Pascal
P
Chavanet
Thierry
T
May
Christian
C
Rabaud
D000328:Adult; D018791:CD4 Lymphocyte Count; D042241:Early Diagnosis; D005260:Female; D005602:France / Q000453:epidemiology; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D006801:Humans; D008297:Male; D016012:Poisson Distribution; D012111:Residence Characteristics / Q000706:statistics & numerical data; D019562:Viral Load / Q000187:drug effects