The association of epicardial adipose tissue with coronary artery calcification among HIV-infected men.
Little data exist regarding the association of epicardial adipose tissue (EAT) and cardiovascular disease among HIV-infected persons. Among 213 HIV-infected men, there was a significant association between protease inhibitor use and increasing EAT volume. EAT was significantly associated with coronary artery calcium greater than 100. The elevated coronary artery disease risk in HIV-infected men may be partially explained by EAT associated with protease inhibitor use.
Infectious Disease Clinic, Naval Medical Center San Diego, San Diego, CA 92134-1005, USA. nancy.crum@med.navy.mil
Nancy F
NF
Crum-Cianflone
Nazima
N
Kathiria
Susan
S
Shauger
Kathleen
K
Love
Gilbert
G
Boswell
D000273:Adipose Tissue / Q000000981:diagnostic imaging*; D000328:Adult; D002114:Calcinosis / Q000000981:diagnostic imaging*; D003324:Coronary Artery Disease / Q000150:complications / Q000000981:diagnostic imaging*; D003430:Cross-Sectional Studies; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy*; D017320:HIV Protease Inhibitors / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014057:Tomography, X-Ray Computed / Q000379:methods
D017320:HIV Protease Inhibitors