3,4-Dihydroxycinnamic acid attenuates the fatigue and improves exercise tolerance in rats.
3,4-Dihydroxycinnamic acid (3,4-DA) is a natural compound with high antioxidant potential found in various foods. This study found that animals administered with 3,4-DA had higher exercise tolerance, reduced blood lactate, and markers of hepatic oxidation. Blood glucose and antioxidant enzymes were not affected by this treatment. 3,4-DA may have applicability in reducing the fatigue associated with exercise.
Department of General Biology, Federal University of Viçosa, MG, Brazil. romuonovaes@yahoo.com.br
Rômulo D
RD
Novaes
Reggiani V
RV
Gonçalves
Maria do Carmo G
Mdo C
Peluzio
Antônio J
AJ
Natali
Izabel R S C
IR
Maldonado
D000284:Administration, Oral; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage*; D001786:Blood Glucose / Q000032:analysis; D002109:Caffeic Acids / Q000008:administration & dosage*; D017079:Exercise Tolerance / Q000187:drug effects* / Q000502:physiology; D005221:Fatigue / Q000378:metabolism / Q000517:prevention & control*; D007773:Lactates / Q000097:blood; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D018384:Oxidative Stress / Q000187:drug effects; D010805:Physical Conditioning, Animal; D051381:Rats; D017208:Rats, Wistar
D000975:Antioxidants; D001786:Blood Glucose; D002109:Caffeic Acids; D007773:Lactates; C040048:caffeic acid