[Evaluation of the Helicobacter pylori stool antigen test].
OBJECTIVE
To evaluate the clinical value of an enzyme-linked immunosorbent assay by the Helicobacter pylori stool antigen (HpSA) test for the detection of H. pylori infection.


METHODS
328 patients were measured upper gastrointestinal endoscopic examination which as gold standards and HpSA test in the meantime, comparing accuracy, sensitivity, specificity and other Indicators.


RESULTS
In the diagnosis of Hp infection, HpSA test had no significant difference comparing with gold standards and had a P value of over 0.5. The sensitivity of HpSA test was 94.6%, while the specificity, veracity, expected positive value, and expected negative value were 96.9%, 96.3%, 89.7% and 98.4%, respectively.


CONCLUSIONS
The H. pylori stool antigen test is a simple, non-invasive method for accurate diagnosis of H. pylori infection.
Center of Clinical Laboratory, The No. 302 Hospital of The PLA, Beijing 100039, China.
Jing-Xia
JX
Guo
Jun
J
Han
Lin
L
Chen
Jun
J
Xu
Jia
J
Liu
Jing
J
Zhao
Ai-Xia
AX
Liu
Li-Hua
LH
Yang
Yong-Ji
YJ
Song
Bo-An
BA
Li
Yuan-Li
YL
Mao
D000293:Adolescent; D000328:Adult; D000368:Aged; D000942:Antigens, Bacterial / Q000032:analysis*; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods*; D005243:Feces / Q000382:microbiology*; D005260:Female; D016481:Helicobacter Infections / Q000175:diagnosis; D016480:Helicobacter pylori / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity
D000942:Antigens, Bacterial