A rivastigmine-precipitated manic episode in a patient with Alzheimer-type dementia.
The occurrence of mania in the geriatric population is rare. Furthermore, there were only six case reports of elderly patients with secondary mania resulting from treatment with cholinesterase inhibitors. In all cases, patients had a prior psychiatric history. We report the case of an elderly patient with no prior history of psychiatric or other organic disorders who experienced first episode mania following treatment with rivastigmine. We discuss the possible mechanism of mania in this patient.
Department of Diving Medicine, Zuoying Armed Forces General Hospital, Kaohsiung, Taiwan, ROC. pierrens@mail.ndmctsgh.edu.tw
Wei-Shih
WS
Tseng
Nian-Sheng
NS
Tzeng
D000368:Aged; D000544:Alzheimer Disease / Q000188:drug therapy* / Q000523:psychology; D001714:Bipolar Disorder / Q000139:chemically induced*; D006801:Humans; D008297:Male; D018696:Neuroprotective Agents / Q000009:adverse effects* / Q000627:therapeutic use; D048448:Phenylcarbamates / Q000009:adverse effects*; D000068836:Rivastigmine
D018696:Neuroprotective Agents; D048448:Phenylcarbamates; D000068836:Rivastigmine