Palladium-catalyzed Hiyama couplings of α-silylenoates and α-silylenamides.
The Hiyama couplings of both α-silylenoates and α-silylenamides are described. These sensitive substrate classes require particularly specific conditions, employing both appropriate silicon-based species and a silver additive to realize high yields of the coupling products. Regioselective platinum-catalyzed hydrosilylations provide a direct and convenient entry into these stereodefined trisubstituted alkenes.
Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA.
Douglas A
DA
Rooke
Eric M
EM
Ferreira
D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*; D013237:Stereoisomerism
D000475:Alkenes; D000480:Alkynes; D000577:Amides; D009942:Organometallic Compounds; D012821:Silanes; D010165:Palladium