Occurrence of killer yeasts in isolates of clinical origin.
A total of 1 025 strains belonging to different Candida species of clinical origin   were evaluated for their killer activity against sensitive strains of Saccharomyces cerevisiae.   Isolates were identified by standard morphological and biochemical analyses. For the   evaluation of the killer activity, potential killer isolates were streaked on plates previously   seeded with the sensitive strain. A total of 52 Candida isolates (5%) exhibited killer activity   against both sensitive yeast strains. The occurrence of the killer phenomenon was   proportionally higher in isolates recovered from closed cavities. Candida glabrata was the   species with the most occurrences of killer strains, but a bigger proportion of killer activity   was observed in Candida utilis. Secretion of killer toxins could represent at least partially, an   advantage against other candida and non-Candida strains in the colonization process,   especially for uncommon Candida species.
Departamento de Microbiología e Inmunología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Nuevo León, México.
E
E
Robledo-Leal
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L
Villarreal-Treviño
G M
GM
González
D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D002175:Candida / Q000737:chemistry / Q000302:isolation & purification* / Q000472:pathogenicity; D002177:Candidiasis / Q000382:microbiology; D025141:Drug Resistance, Fungal; D006801:Humans; D055646:Killer Factors, Yeast / Q000737:chemistry / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009183:Mycotoxins / Q000737:chemistry / Q000494:pharmacology*; D012441:Saccharomyces cerevisiae / Q000187:drug effects*; D013045:Species Specificity
D000935:Antifungal Agents; D055646:Killer Factors, Yeast; D009183:Mycotoxins