Takayasu arteritis developing during treatment of ulcerative colitis with infliximab.
A 22-year-old female with ulcerative colitis that was successfully treated with infliximab (IFX), and remained stable following tapered discontinuation of prednisolone, developed anterior neck pain and elevation of C-reactive protein following her fourth administration of IFX. She was diagnosed with Takayasu arteritis (TA) based on neck ultrasound and computed tomography angiography. This is the first report describing the development of TA during treatment of UC with IFX.
Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. yoshirohorai0518@yahoo.co.jp
Yoshiro
Y
Horai
Oka
O
Satoru
Samuel
S
Lapalme-Remis
Remi
R
Sumiyoshi
Yoshikazu
Y
Nakashima
Takahisa
T
Suzuki
Akitomo
A
Okada
Shin-Ya
SY
Kawashiri
Kunihiro
K
Ichinose
Mami
M
Tamai
Satoshi
S
Yamasaki
Hideki
H
Nakamura
Fuminao
F
Takeshima
Tomoki
T
Origuchi
Atsushi
A
Kawakami
D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D003093:Colitis, Ulcerative / Q000150:complications* / Q000188:drug therapy*; D005260:Female; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D006801:Humans; D000069285:Infliximab; D013625:Takayasu Arteritis / Q000150:complications* / Q000175:diagnosis; D055815:Young Adult
D000911:Antibodies, Monoclonal; D005765:Gastrointestinal Agents; D000069285:Infliximab