Unsymmetrical tetrasubstituted ureas from tertiary carbamoylimidazole: activation by AlMe3.
An efficient and general method for the synthesis of unsymmetrical tetrasubstituted ureas from carbamoylimidazole is described. The conversion is achieved by the concurrent quarternization of the imidazole nitrogen and activation of amines with AlMe(3).
Department of Chemistry, Hindustan University, Rajiv Gandhi Salai, Padur, (Via) Kelambakkam, Chennai 603 103, India.
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A
Velavan
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Sumathi
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Balasubramanian
D000535:Aluminum / Q000737:chemistry*; D000588:Amines / Q000138:chemical synthesis / Q000737:chemistry; D002219:Carbamates / Q000138:chemical synthesis / Q000737:chemistry*; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry; D014508:Urea / Q000031:analogs & derivatives* / Q000138:chemical synthesis* / Q000737:chemistry
D000588:Amines; D002219:Carbamates; D007093:Imidazoles; D009942:Organometallic Compounds; D014508:Urea; D000535:Aluminum; D009584:Nitrogen