Past, present and future of cardiac resynchronization.
The growing interest in dyssynchrony and cardiac resynchronization therapy has opened the field of cardiac stimulation to new haemodynamic indications. French investigators have played a key role in the formulation of new concepts, all arising from clinical observations, and the development (in collaboration with industry) and clinical evaluation of resynchronization devices. This review summarizes recent knowledge and perspectives pertaining to atrial, atrioventricular and ventricular dyssynchrony and resynchronization. Some of these concepts have been validated by robust clinical evidence, on the basis of which scientific recommendations have been formulated. Other concepts have been less successful but probably merit further attention.
Service de cardiologie et maladies vasculaires, hôpital Pontchaillou-CHU, Rennes, France. jean-claude.daubert@chu-rennes.fr
Claude
C
Daubert
Serge
S
Cazeau
Philippe
P
Ritter
Christophe
C
Leclercq
D000328:Adult; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000266:history / Q000503:physiopathology / Q000628:therapy*; D058406:Cardiac Resynchronization Therapy / Q000266:history / Q000639:trends; D058409:Cardiac Resynchronization Therapy Devices / Q000266:history / Q000639:trends; D004867:Equipment Design; D005260:Female; D005544:Forecasting; D006329:Heart Conduction System / Q000503:physiopathology; D006439:Hemodynamics; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome