Amoxicillin/clavulanic acid-induced pemphigus vulgaris: case report.
Drug-induced pemphigus is a well-established variety of pemphigus, presenting with clinical and histopathologic features identical to idiopathic form. Medical history plays a fundamental role in the diagnosis of drug-induced pemphigus. A large variety of drugs have been implicated in its pathogenesis and they may induce acantholysis via biochemical and/or immune mechanism. We present a case of a 69-year-old woman affected by amoxicillin/clavulanic acid-induced pemphigus and discuss its pathogenetic mechanism.
Department of Dermatology and Venereology, Second University of Naples, Naples, Italy. adone.baroni@gmail.com
Adone
A
Baroni
Teresa
T
Russo
Franco
F
Faccenda
Vincenzo
V
Piccolo
D000368:Aged; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000009:adverse effects*; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D010392:Pemphigus / Q000139:chemically induced* / Q000276:immunology / Q000473:pathology / Q000503:physiopathology
D000900:Anti-Bacterial Agents; D019980:Amoxicillin-Potassium Clavulanate Combination