[Effect of delta-sleep inducing peptide on the functional activity of some organs and tissues of rats during physiological aging].
The authors show that exogenous delta-sleep inducing peptide (DSIP) injected subcutaneously to the rats in the age of 2-24 months of postnatal development in a dose of 100 mg/kg of animal body weight in courses for 5 consecutive days every month, has a hepatoprotective effect. DSIP does not affect the functional activity of the pancreas, and is not involved in the regulation of calcium homeostasis in the physiological aging of the organism.
T I
TI
Bondarenko
E A
EA
Maĭboroda
I I
II
Mikhaleva
I A
IA
Prudchenko
D000375:Aging / Q000187:drug effects* / Q000502:physiology; D000818:Animals; D002118:Calcium / Q000097:blood*; D003701:Delta Sleep-Inducing Peptide / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D007279:Injections, Subcutaneous; D008099:Liver / Q000187:drug effects* / Q000502:physiology; D008111:Liver Function Tests; D008297:Male; D010179:Pancreas / Q000187:drug effects* / Q000502:physiology; D010186:Pancreatic Function Tests; D051381:Rats; D016896:Treatment Outcome
D003701:Delta Sleep-Inducing Peptide; D002118:Calcium