High yield of reinfections by home-based automatic rescreening of Chlamydia positives in a large-scale register-based screening programme and determinants of repeat infections.
BACKGROUND
In a systematic internet-based Chlamydia Screening Implementation Programme in The Netherlands, all chlamydia-positive participants automatically received a testkit after 6 months to facilitate early detection of repeat infections. The authors describe participation in repeat testing and prevalence and determinants of repeat infection during three consecutive annual screening rounds.


METHODS
Data collection included information on testkits sent, samples received and results of laboratory tests at time of baseline test and retest; (sexual) behavioural variables and socio-demographic variables were assessed. Chlamydia positives were requested to answer additional questions about treatment and partner notification 10 days after checking their results.


RESULTS
Retest rate was 66.3% (2777/4191). Retest chlamydia positivity was 8.8% (242/2756) compared with a chlamydia positivity at first screening test of 4.1%. Chlamydia positivity was significantly higher in younger age groups (14.6% in 16-19 years, 8.5% and 5.5% in 20-24 and 25-29 years; p<0.01); in participants with lower education (15.2% low, 11.1% medium and 5.1% high; p<0.001) and in Surinamese/Antillean (13.1%), Turkish/Moroccan (12.9%) and Sub-Saharan African participants (18.6%; p<0.01). At baseline, 88.7% infected participants had reportedly been treated and treatment of current partner was 80.1%.


CONCLUSIONS
Automated retesting by sending a testkit after 6 months to all chlamydia positives achieved high retest uptake and yielded a positivity rate twice as at baseline and can therefore be recommended as an additional strategy for chlamydia control. The high rate of repeat infections among known risk groups suggests room for improvement in patient case management and in effective risk reduction counselling.
Department of Infectious Disease Control, Rotterdam Rijnmond Public Health Service, Rotterdam, The Netherlands. hm.gotz@rotterdam.nl
Hannelore M
HM
Götz
Ingrid V F
IV
van den Broek
Christian J P A
CJ
Hoebe
Elfi E H G
EE
Brouwers
Lydia L
LL
Pars
Johan S A
JS
Fennema
Rik H
RH
Koekenbier
Sander
S
van Ravesteijn
Eline L M
EL
Op de Coul
Jan
J
van Bergen
D000293:Adolescent; D000328:Adult; D001431:Bacteriological Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D008219:Lymphogranuloma Venereum / Q000175:diagnosis* / Q000453:epidemiology*; D008297:Male; D008403:Mass Screening / Q000379:methods*; D009426:Netherlands / Q000453:epidemiology; D019095:Point-of-Care Systems; D015995:Prevalence; D012008:Recurrence; D012646:Self Administration / Q000379:methods*; D055815:Young Adult