Proteomics: methodologies and applications to the study of human diseases.
Proteomic approach has allowed large-scale studies of protein expression in different tissues and body fluids in discrete conditions and/or time points. Recent advances of methodologies in this field have opened new opportunities to obtain relevant information on normal and abnormal processes occurring in the human body. In the current report, the main proteomics techniques and their application to human disease study are reviewed.
Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brazil.
Eduardo Buzolin
EB
Barbosa
Alessandra
A
Vidotto
Giovana Mussi
GM
Polachini
Tiago
T
Henrique
Alessandra Bernadete Trovó de
AB
Marqui
Eloiza Helena
EH
Tajara
D001826:Body Fluids / Q000737:chemistry*; D002850:Chromatography, Gel; D004194:Disease / Q000235:genetics*; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D013058:Mass Spectrometry; D040901:Proteomics / Q000379:methods*