High expression of CD20+ lymphocytes in soft tissue sarcomas is a positive prognostic indicator.
The immune status is important in cancer patients. Tissue microarrays from 249 patients with soft tissue sarcomas were constructed. Immunohistochemistry was used to evaluate the CD3+, CD4+, CD8+, CD20+ and CD45+ lymphocytes in tumors. High density of CD20+ lymphocytes is an independent positive prognostic indicator for these patients.
Dept. of Clinical Pathology, University Hospital of North Norway; Tromso, Norway ; Institute of Medical Biology, University of Tromso; Tromso, Norway.
Sveinung W
SW
Sorbye
Thomas
T
Kilvaer
Andrej
A
Valkov
Tom
T
Donnem
Eivind
E
Smeland
Khalid
K
Al-Shibli
Roy M
RM
Bremnes
Lill-Tove
LT
Busund