Development of the sensory nervous system in the vertebrate head: the importance of being on time.
Sense organs and cranial sensory ganglia are functionally diverse, yet share a common developmental origin. They arise from a pool of multipotent progenitors and local signals gradually restrict their development potential to specify the inner ear, olfactory epithelium, lens and sensory neurons. This process requires the temporal integration of multiple signalling pathways, cross-repressive transcription factor interactions and tight coordination of cell fate specification and morphogenesis.
Department of Craniofacial Development and Stem Cell Biology, King's College London, London SE1 9RT, UK.
Laura
L
Lleras-Forero
Andrea
A
Streit
D000818:Animals; D001921:Brain / Q000166:cytology / Q000196:embryology* / Q000378:metabolism; D019070:Cell Lineage; D006801:Humans; D009420:Nervous System / Q000166:cytology / Q000196:embryology* / Q000378:metabolism; D015398:Signal Transduction; D014157:Transcription Factors / Q000378:metabolism; D014714:Vertebrates / Q000196:embryology* / Q000378:metabolism
D014157:Transcription Factors