Antiplatelet and anticoagulation strategies in the prevention and treatment of ischemic stroke.
Stroke prevention is highly effective but underutilized in medical care. Lifestyle modification, in the form of diet, exercise, smoking cessation, antihypertensive therapy, close control of diabetes and hyperlipidemia, can prevent most strokes. Selected subgroups can benefit from carotid surgery or stenting, anticoagulation for atrial fibrillation, and antiplatelet therapy. Evidence for these approaches and alternative management strategies are discussed.
Department of Neurology, A- 0118 Medical Center North, Vanderbilt University School of Medicine, Nashville, TN 37232-2551, USA. howard.kirshner@vanderbilt.edu
Howard S
HS
Kirshner
D000818:Animals; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use*; D015897:Comorbidity; D057510:Endovascular Procedures; D006801:Humans; D002546:Ischemic Attack, Transient / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control*; D018579:Patient Selection; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D017410:Practice Guidelines as Topic; D011322:Primary Prevention; D012307:Risk Factors; D040242:Risk Reduction Behavior; D055502:Secondary Prevention; D020521:Stroke / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control*; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures
D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors