title: Biochemical markers of psoriasis as a metabolic disease.
abstract: Psoriasis is a chronic immune mediated inflammatory skin disease with a population prevalence of 2-3%. In recent years, psoriasis has been recognized as a systemic disease associated with metabolic syndrome or its components such as: obesity, insulin resistance, hypertension and atherogenic dyslipidemia. Many bioactive substances have appeared to be related to metabolic syndrome. Based on current literature, we here discuss the possible role of adiponectin, leptin, ghrelin, resistin, inflammatory cytokines, plasminogen activator inhibitor 1, uric acid, C-reactive protein and lipid abnormalities in psoriasis and in metabolic syndrome.
authors: Department of Dermatology, Venereology and Pediatric Dermatology, Medical University of Lublin, Poland. agerkowicz@wp.pl
authors: Agnieszka
authors: A
authors: Gerkowicz
authors: Aldona
authors: A
authors: Pietrzak
authors: Jacek Cezary
authors: JC
authors: Szepietowski
authors: Sebastian
authors: S
authors: Radej
authors: Grażyna
authors: G
authors: Chodorowska
mesh_terms: D015415:Biomarkers / Q000378:metabolism*; D006801:Humans; D008659:Metabolic Diseases / Q000378:metabolism*; D011565:Psoriasis / Q000378:metabolism*
chemical_list: D015415:Biomarkers