title: Caloric restriction in mTORC1 control of intestinal homeostasis.
abstract: Reducing caloric intake, while maintaining adequate nutrition, promotes longevity in diverse organisms, possibly by preserving stem and progenitor cell function. Yilmaz and colleagues (2012) now show that caloric restriction alters intestinal stem cell proliferation and differentiation, and elucidate a mechanism for how the mammalian stem cell niche responds to environmental inputs.
authors: Thurl E
authors: TE
authors: Harris
authors: Michael O
authors: MO
authors: Thorner