title: A role for period 2 in cardioprotection.
abstract: How adenosine receptors protect the ischemic heart is not completely understood. Eckle et al. (2012) now show that signaling through adenosine receptor 2b (Adora2b) stabilizes a circadian rhythm protein, period 2 (Per2), resulting in the stabilization of hypoxia-inducible factor-1α (HIF-1α), upregulation of glycolysis, and cardioprotection from ischemia.
authors: Gary D
authors: GD
authors: Lopaschuk
authors: Jagdip S
authors: JS
authors: Jaswal