title: [Clinical research on treatment of migraine with pine needle moxibustion].
abstract: OBJECTIVE
  To observe the clinical effect and mechanism of migraine treated with pine needle moxibustion.
  
  
  METHODS
  Forty-three patients were randomly divided into 2 groups of pine needle moxibustion group (group A, 21 cases) and medicated thread moxibustion of Zhuang medicine group (group B, 22 cases). Same acu-points were selected as the main points for both groups, namely Fengchi (GB 20), Baihui (GV 20), Taiyang (EX-HN 5), Shuaigu (GB 8), Cuanzhu (BL 2), Sizhukong (TE 23), Yanglingquan (GB 34), Waiguan (TE 5) and Ashi points. Pine needle moxibustion was applied for the group A. Processed lighted pine needles were banded together with one even head to do moxibustion on acupoints or pain points. While, lighted medicated thread was adopted for the group B to do moxibustion. Therapeutic effects, the content of high-sensitivity C-reactive protein (hs-CRP), Mg2+ in the serum and the degree of pain of the two groups were compared.
  
  
  RESULTS
  (1) In the group A, the complete remission rate was 47.6% (10/21) and the effective rate was 90.5% (19/21). In the group B, the complete remission rate was 13.6% (3/22) and the effective rate was 50.0% (11/22). The two rates in the group A were superior to those in the group B (both P < 0.01); (2) In the group A, the content of hs-CRP was decreased from (4.29 +/- 0.98) mg/L to (2.11 +/- 0.87) mg/L, and Mg2+ was increased from (0.67 +/- 0.28) mmol/L to (1.07 +/- 0.16) mmol/L. In the group B, the contents of the above mentioned indices were respectively decreased from (4.30 +/- 1.07) mg/L to (3.38 +/- 1.15) mg/L and increased from (0.68 +/- 0.21) mmol/L to (0.88 +/- 0.25) mmol/L. There were significant differences between the two groups after treatment (both P < 0.05). (3) The degree of pain in the group A after treatment was much lower than that in the group B (P < 0.05).
  
  
  CONCLUSIONS
  The clinical effect of migraine treated with pine needle moxibustion is better than that with the medicated thread moxibustion of Zhuang medicine. And it has obvious regulation effect on the levels of hs-CRP and Mg2+ in the serum of patients.
authors: Department of TCM, the First People's Hospital of Fangchenggang City, Fangchenggang 538021, Guangxi Zhuang Autonomous Region, China. mengweiguang@163.com
authors: Wei-guang
authors: WG
authors: Meng
authors: Lai
authors: L
authors: Shi
authors: Ling-yan
authors: LY
authors: Wu
authors: Ling-yan
authors: LY
authors: Lai
authors: Rui-xia
authors: RX
authors: Song
authors: Shao-zhen
authors: SZ
authors: Huang
mesh_terms: D015669:Acupuncture Points; D000293:Adolescent; D000328:Adult; D002097:C-Reactive Protein / Q000378:metabolism; D005260:Female; D006801:Humans; D008274:Magnesium / Q000097:blood; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000378:metabolism / Q000628:therapy*; D009071:Moxibustion; D055815:Young Adult
chemical_list: D002097:C-Reactive Protein; D008274:Magnesium