title: Iron-catalyzed alkylations of aryl sulfamates and carbamates.
abstract: The alkylation of aryl sulfamates and carbamates using iron catalysis is reported. The method constructs sp(2)-sp(3) carbon-carbon bonds and provides synthetically useful yields across a range of substrates (>35 examples). The directing group ability of sulfamates and carbamates, accompanied by their low reactivity toward conventional cross-couplings, renders these substrates useful for the synthesis of polyfunctionalized arenes.
authors: Department of Chemistry and Biochemistry, University of California , Los Angeles, California 90095-1569, United States.
authors: Amanda L
authors: AL
authors: Silberstein
authors: Stephen D
authors: SD
authors: Ramgren
authors: Neil K
authors: NK
authors: Garg
mesh_terms: D000478:Alkylation; D002219:Carbamates / Q000737:chemistry*; D002384:Catalysis; D007501:Iron / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D013451:Sulfonic Acids / Q000737:chemistry*
chemical_list: D002219:Carbamates; D013451:Sulfonic Acids; C005741:sulfamic acid; D007501:Iron