title: Sequential decision tree using the analytic hierarchy process for decision support in rectal cancer.
abstract: OBJECTIVE
  The aim of the study is to determine the most appropriate method for construction of a sequential decision tree in the management of rectal cancer, using various patient-specific criteria and treatments such as surgery, chemotherapy, and radiotherapy.
  
  
  METHODS
  An analytic hierarchy process (AHP) was used to determine the priorities of variables. Relevant criteria used in two decision steps and their relative priorities were established by a panel of five general surgeons. Data were collected via a web-based application and analyzed using the "Expert Choice" software specifically developed for the AHP. Consistency ratios in the AHP method were calculated for each set of judgments, and the priorities of sub-criteria were determined. A sequential decision tree was constructed for the best treatment decision process, using priorities determined by the AHP method.
  
  
  RESULTS
  Consistency ratios in the AHP method were calculated for each decision step, and the judgments were considered consistent. The tumor-related criterion "presence of perforation" (0.331) and the patient-surgeon-related criterion "surgeon's experience" (0.630) had the highest priority in the first decision step. In the second decision step, the tumor-related criterion "the stage of the disease" (0.230) and the patient-surgeon-related criterion "surgeon's experience" (0.281) were the paramount criteria. The results showed some variation in the ranking of criteria between the decision steps. In the second decision step, for instance, the tumor-related criterion "presence of perforation" was just the fifth.
  
  
  CONCLUSIONS
  The consistency of decision support systems largely depends on the quality of the underlying decision tree. When several choices and variables have to be considered in a decision, it is very important to determine priorities. The AHP method seems to be effective for this purpose. The decision algorithm developed by this method is more realistic and will improve the quality of the decision tree.
authors: Dokuz Eylül University, Faculty of Science, Department of Statistics, 35160 Tınaztepe, Buca, İzmir, Turkey. asli.suner@deu.edu.tr
authors: Aslı
authors: A
authors: Suner
authors: Can Cengiz
authors: CC
authors: Çelikoğlu
authors: Oğuz
authors: O
authors: Dicle
authors: Selman
authors: S
authors: Sökmen
mesh_terms: D000465:Algorithms; D003661:Decision Support Techniques; D003663:Decision Trees; D019788:Fluorodeoxyglucose F18; D006801:Humans; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D012004:Rectal Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18