title: Usefulness of ultrasonography-proven tenosynovitis to monitor disease activity of a patient with very early rheumatoid arthritis treated by abatacept.
abstract: We introduced abatacept (ABT) in a very early rheumatoid arthritis (RA) patient with active tenosynovitis of hands defined by musculoskeletal ultrasonography (MSKUS). MSKUS-proven tenosynovitis remarkably improved at 2 months in spite of clinical exacerbation, followed by clinical remission at 5 months. MSKUS abnormalities also disappeared. Although ABT was discontinued due to an adverse event after the sixth infusion, she remained in clinical remission as well as imaging remission by MSKUS at 13 months.
authors: Department of Immunology and Rheumatology, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan. shin-ya@hotmail.co.jp
authors: Shin-ya
authors: SY
authors: Kawashiri
authors: Keita
authors: K
authors: Fujikawa
authors: Ayako
authors: A
authors: Nishino
authors: Takahisa
authors: T
authors: Suzuki
authors: Akitomo
authors: A
authors: Okada
authors: Hideki
authors: H
authors: Nakamura
authors: Atsushi
authors: A
authors: Kawakami
mesh_terms: D000069594:Abatacept; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging* / Q000188:drug therapy; D005260:Female; D006225:Hand / Q000000981:diagnostic imaging*; D006801:Humans; D018796:Immunoconjugates / Q000627:therapeutic use*; D008875:Middle Aged; D012074:Remission Induction; D013717:Tenosynovitis / Q000000981:diagnostic imaging* / Q000188:drug therapy; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D018501:Antirheumatic Agents; D018796:Immunoconjugates; D000069594:Abatacept