title: Endocarditis with ruptured sinus of Valsalva aneurysm caused by nonvaccine Streptococcus pneumoniae serotype 21.
abstract: Sinus of Valsalva aneurysm is a rare, catastrophic complication of endocarditis. We report an unusual case of ruptured sinus of Valsalva aneurysm associated with endocarditis that was caused by Streptococcus pneumoniae serotype 21. The patient, a 12-year-old girl, underwent surgical repair of the aneurysm and was given intravenous antibiotics for 6 weeks. She was doing well at the 6-week follow-up visit. This case is unusual because of the patient's young age at presentation, the absence of predisposing factors, and the isolation of a nonvaccine serotype 21, which revealed the epidemiologic changes of invasive pneumococcal disease. To our knowledge, this is the first reported case of endocarditis caused by this S. pneumoniae serotype.
authors: Departments of Pediatrics, Children's Hospital of Shreveport, Shreveport, Louisiana 71130, USA.
authors: Kamakshya P
authors: KP
authors: Patra
authors: John A
authors: JA
authors: Vanchiere
authors: Joseph A
authors: JA
authors: Bocchini
authors: Amy C
authors: AC
authors: Wu
authors: Robert D
authors: RD
authors: Jackson
authors: Ernest A
authors: EA
authors: Kiel
authors: Dennis
authors: D
authors: Mello
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001014:Aortic Aneurysm / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D001019:Aortic Rupture / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D001021:Aortic Valve / Q000382:microbiology* / Q000601:surgery; D002648:Child; D003646:Debridement; D018618:Echocardiography, Doppler, Color; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D011008:Pneumococcal Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D012850:Sinus of Valsalva / Q000382:microbiology* / Q000601:surgery; D013296:Streptococcus pneumoniae / Q000302:isolation & purification*; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures
chemical_list: D000900:Anti-Bacterial Agents