title: Cancer incidence in a sample of Maryland residents with serious mental illness.
abstract: OBJECTIVE
  Persons with serious mental illness have an increased mortality rate and a higher burden of many medical conditions compared with persons without serious mental illness. Cancer risk in the population with serious mental illness is uncertain, and its incidence was examined by race, sex, and cancer site in a community-based cohort of adults with schizophrenia or bipolar disorder.
  
  
  METHODS
  The authors calculated standardized incidence ratios of total and site-specific cancers in a cohort of 3,317 Maryland Medicaid adult beneficiaries with schizophrenia or bipolar disorder followed from 1994 through 2004 for comparison with the U.S. population.
  
  
  RESULTS
  Total cancer incidence for adults with schizophrenia or bipolar disorder was 2.6 times higher in the cohort. Elevated risk was greatest for cancer of the lung. No differences in risk were found for African-American versus white Medicaid beneficiaries with serious mental illness.
  
  
  CONCLUSIONS
  These findings suggest that there is a heightened risk of cancer among adults with schizophrenia or bipolar disorder. Clinicians should promote appropriate cancer screening and work to reduce modifiable risk factors, such as smoking, among persons with serious mental illness.
authors: Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21287, USA.
authors: Emma Elizabeth
authors: EE
authors: McGinty
authors: Yiyi
authors: Y
authors: Zhang
authors: Eliseo
authors: E
authors: Guallar
authors: Daniel E
authors: DE
authors: Ford
authors: Donald
authors: D
authors: Steinwachs
authors: Lisa B
authors: LB
authors: Dixon
authors: Nancy L
authors: NL
authors: Keating
authors: Gail L
authors: GL
authors: Daumit
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000453:epidemiology*; D001943:Breast Neoplasms / Q000453:epidemiology; D015331:Cohort Studies; D015179:Colorectal Neoplasms / Q000453:epidemiology; D015897:Comorbidity; D005260:Female; D006801:Humans; D015994:Incidence; D008175:Lung Neoplasms / Q000453:epidemiology; D008297:Male; D008396:Maryland / Q000453:epidemiology; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology*; D012189:Retrospective Studies; D012559:Schizophrenia / Q000453:epidemiology*; D012907:Smoking