title: Review of vasopressin use in gynecologic surgery.
abstract: Vasopressin has been used in gynecologic surgery since the 1950s. Since its initial introduction, multiple applications of vasopressin have been explored. The expansion of vasopressin usage in gynecologic surgery is being fueled in part by the increase in minimally invasive surgical techniques, in which alternative methods of temporary hemostasis are in high demand. Nevertheless, much criticism has been directed toward use of vasopressin because of reports of serious complications including cardiac arrest. These concerns have caused several countries to restrict or prohibit the use of this valuable drug. This review explores the mechanisms of vasopressin, the current literature on vasopressin use in gynecologic surgery, and evaluates the reported complications associated with vasopressin use.
authors: Department of Obstetrics and Gynecology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York 10467, USA. schudnof@montefiore.org
authors: Scott
authors: S
authors: Chudnoff
authors: Sivan
authors: S
authors: Glazer
authors: Mark
authors: M
authors: Levie
mesh_terms: D002318:Cardiovascular Diseases / Q000139:chemically induced*; D005260:Female; D013509:Gynecologic Surgical Procedures; D006488:Hemostasis, Surgical; D006801:Humans; D013530:Surgical Wound Infection / Q000139:chemically induced*; D014662:Vasoconstrictor Agents / Q000009:adverse effects / Q000627:therapeutic use*; D014667:Vasopressins / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D014662:Vasoconstrictor Agents; D014667:Vasopressins