title: [Verification of histologic diagnosis in cervical carcinoma in situ with contradictory morphological data].
abstract: The medical technology of in situ cervical carcinoma cytological verification using computer-assisted morphometric and density analysis of atypical cells nuclei was developed. The technology is aimed at diagnosis verification in cases with contradictory morphological data. The malignant transformation of cervical epithelium undetectable by conventional morphology methods can be diagnosed using the Felgen-stained samples nuclear DNA distribution data. The right DNA distribution diagram shift with modal class 4C or higher, mean DNA contents higher than 4C, the ratio between aneuploidic and polyploidic cells higher than 0.2 are the signs of cervical epithelium malignant transformation.
authors: V I
authors: VI
authors: Novik
mesh_terms: D000328:Adult; D000368:Aged; D002278:Carcinoma in Situ / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D002583:Uterine Cervical Neoplasms / Q000473:pathology*