title: Atorvastatin-related thrombocytopenic purpura.
abstract: A 44-year-old male patient with a single vessel ischaemic heart disease was referred to the lipid clinic for management of hypercholesterolaemia after an episode of admission with thrombocytopenic purpura secondary to atorvastatin. Atorvastatin was discontinued and his platelet counts improved gradually with steroids. He is now established on a different statin with no further episodes of thrombocytopenia. Though a drug challenge was never done, an idiosyncratic reaction to the initial statin seems to be the most likely cause.
authors: Clinical Biochemistry, Pathology Department, Hull Royal Infirmary, Hull, UK. deepan@doctors.org.uk
authors: Deepa
authors: D
authors: Narayanan
authors: Eric S
authors: ES
authors: Kilpatrick
mesh_terms: D000328:Adult; D000924:Anticholesteremic Agents / Q000009:adverse effects*; D000069059:Atorvastatin; D006538:Heptanoic Acids / Q000009:adverse effects*; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy*; D008297:Male; D011696:Purpura, Thrombocytopenic / Q000139:chemically induced*; D011758:Pyrroles / Q000009:adverse effects*
chemical_list: D000924:Anticholesteremic Agents; D006538:Heptanoic Acids; D011758:Pyrroles; D000069059:Atorvastatin