title: Hemoglobin aggregates studied under static and dynamic conditions involving the formation of nanobacteria-like structures.
abstract: Laser light scattering and scanning electron microscopy (SEM) are used to study hemoglobin in the aqueous phase. The impact that salts [NaCl, Ca₃(PO₄)₂] and iron oxide nanoparticles have on the hemoglobin size are also studied. The first set of experiments examined hemoglobin aggregates in the aqueous phases in the presence of salts and nanoparticles. Aqueous phase samples were then dehydrated and examined using SEM. The resulting structures resemble those observed in nanobacteria studies conducted in other labs. This study demonstrates that aggregates of hemoglobin and various salts found in a physiological environment can produce structures that resemble nanobacteria.
authors: Department of Chemistry, Valdosta State University, Valdosta, GA, USA.
authors: Jeramy L R
authors: JL
authors: Baum
authors: Riland L
authors: RL
authors: Jones
authors: Thomas J
authors: TJ
authors: Manning
authors: James
authors: J
authors: Nienow
authors: Dennis
authors: D
authors: Phillips
mesh_terms: D059587:Calcifying Nanoparticles / Q000737:chemistry; D002130:Calcium Phosphates / Q000737:chemistry; D011232:Chemical Precipitation; D005290:Ferric Compounds / Q000737:chemistry; D006454:Hemoglobins / Q000737:chemistry* / Q000648:ultrastructure; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D009994:Osmolar Concentration; D010316:Particle Size; D012965:Sodium Chloride / Q000737:chemistry; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D059587:Calcifying Nanoparticles; D002130:Calcium Phosphates; D005290:Ferric Compounds; D006454:Hemoglobins; C000499:ferric oxide; D012965:Sodium Chloride; C018392:tricalcium phosphate