title: Monoamines and assessment of risks.
abstract: Over the past decade, neuroeconomics studies utilizing neurophysiology methods (fMRI or EEG) have flourished, revealing the neural basis of 'boundedly rational' or 'irrational' decision-making that violates normative theory. The next question is how modulatory neurotransmission is involved in these central processes. Here I focused on recent efforts to understand how central monoamine transmission is related to nonlinear probability weighting and loss aversion, central features of prospect theory, which is a leading alternative to normative theory for decision-making under risk. Circumstantial evidence suggests that dopamine tone might be related to distortion of subjective reward probability and noradrenaline and serotonin tone might influence aversive emotional reaction to potential loss.
authors: Department of Psychiatry, Kyoto University Graduate School of Medicine, 54 Shogoin, Kawara-cho, Sakyo-ku, Kyoto 606-8507, Japan. hidehiko@kuhp.kyoto-u.ac.jp
authors: Hidehiko
authors: H
authors: Takahashi
mesh_terms: D015306:Biogenic Monoamines / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D002755:Choice Behavior / Q000502:physiology*; D003657:Decision Making / Q000502:physiology*; D060909:Economics, Behavioral / Q000639:trends; D006801:Humans; D009446:Neurobiology / Q000639:trends; D012309:Risk-Taking
chemical_list: D015306:Biogenic Monoamines