title: Surface analysis using a new plasma assisted desorption/ionisation source for mass spectrometry in ambient air.
abstract: The authors report on a modified micro-plasma assisted desorption/ionisation (PADI) device which creates plasma through the breakdown of ambient air rather than utilising an independent noble gas flow. This new micro-PADI device is used as an ion source for ambient mass spectrometry to analyse species released from the surfaces of polytetrafluoroethylene, and generic ibuprofen and paracetamol tablets through remote activation of the surface by the plasma. The mass spectra from these surfaces compare favourably to those produced by a PADI device constructed using an earlier design and confirm that the new ion source is an effective device which can be used to achieve ambient mass spectrometry with improved spatial resolution.
authors: Department of Electrical Engineering and Electronics, University of Liverpool, L69 3GJ, United Kingdom.
authors: A
authors: A
authors: Bowfield
authors: D A
authors: DA
authors: Barrett
authors: M R
authors: MR
authors: Alexander
authors: C A
authors: CA
authors: Ortori
authors: F M
authors: FM
authors: Rutten
authors: T L
authors: TL
authors: Salter
authors: I S
authors: IS
authors: Gilmore
authors: J W
authors: JW
authors: Bradley
mesh_terms: D000082:Acetaminophen / Q000032:analysis*; D000388:Air; D016568:Drugs, Generic / Q000032:analysis*; D007052:Ibuprofen / Q000032:analysis*; D013058:Mass Spectrometry / Q000295:instrumentation* / Q000379:methods*; D011138:Polytetrafluoroethylene / Q000032:analysis*
chemical_list: D016568:Drugs, Generic; D000082:Acetaminophen; D011138:Polytetrafluoroethylene; D007052:Ibuprofen