title: Measuring working memory deficits in aphasia.
abstract: OBJECTIVE
  Many adults with aphasia demonstrate concomitant deficits in working memory (WM), but such deficits are difficult to quantify because of a lack of validated measures as well as the complex interdependence between language and WM. We examined the feasibility, reliability, and internal consistency of an n-back task for evaluating WM in aphasia, then explored the influence of domain-general (WM load, reaction time, age) and domain-specific (language) factors.
  
  
  METHODS
  Fourteen adults with aphasia and 12 age-and education-matched controls completed n-back tasks varying in stimulus type (high-frequency, low-frequency, or non-nameable stimuli) and WM load (0-, 1-, and 2-back). Data analyses explored the impact of these variables within and across participants and groups.
  
  
  RESULTS
  n-Back scores were collectively reliable across conditions. Both groups performed similarly across stimulus types with significantly greater WM accuracy for nameable versus non-nameable stimuli. Compared to the controls, adults with aphasia were significantly more affected by increasing WM load. RT effects generally paralleled accuracy data, whereas age effects were inconsistent across tasks.
  
  
  CONCLUSIONS
  These data are consistent with WM deficits in aphasia, for which the n-back task holds promise for clinical quantification.
  
  
  OBJECTIVE
  Readers will be able to: (a) define working memory, (b) discuss the difficulty inherent in removing language from a complex cognitive task, and (c) describe how the n-back task may contribute to measuring working memory capacity in individuals with aphasia.
authors: School of Allied Health and Communicative Disorders, Northern Illinois University, DeKalb, IL 60115, USA. jmayer1@niu.edu
authors: Jamie F
authors: JF
authors: Mayer
authors: Laura L
authors: LL
authors: Murray
mesh_terms: D000328:Adult; D000368:Aged; D001037:Aphasia / Q000209:etiology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007807:Language Tests; D008297:Male; D008569:Memory Disorders / Q000150:complications*; D008570:Memory, Short-Term; D008875:Middle Aged; D009483:Neuropsychological Tests; D011930:Reaction Time