title: Dexmedetomidine: a guide to its use for sedation in the US.
abstract: Intravenous dexmedetomidine (Precedex(®)) provides both effective sedation in mechanically ventilated patients in an intensive care setting and effective procedural sedation. In these patient populations, it reduces the need for rescue sedation with intravenous propofol or intravenous midazolam and reduces opioid requirements. In addition, patients receiving dexmedetomidine are calm and easy to arouse and manage. Intravenous dexmedetomidine is generally well tolerated and is not associated with respiratory depression. Although the utilization of dexmedetomidine is associated with hypotension and bradycardia, both usually resolve without intervention.
authors: Adis, Auckland, New Zealand. demail@springer.com
authors: Gillian M
authors: GM
authors: Keating
authors: Sheridan M
authors: SM
authors: Hoy
authors: Katherine A
authors: KA
authors: Lyseng-Williamson
mesh_terms: D020927:Dexmedetomidine / Q000627:therapeutic use*; D017277:Drug Approval; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D006993:Hypnotics and Sedatives; D020927:Dexmedetomidine