title: Emerging invasive nonvaccine pneumoccocal serotype 25.
abstract: Streptococcus pneumoniae (pneumococcus) is a bacterial pathogen that causes invasive infections, including septicemia and meningitis, as well as noninvasive infections such as community-acquired pneumonia, sinusitis and acute otitis media. Vaccination with pneumococcal conjugate vaccine (PCV7) has significantly reduced the burden of pneumococcal disease; however it targets only seven of the more than 92 pneumococcal serotypes. Concerns have been raised that nonvaccine serotypes could increase in prevalence and reduce the benefits of vaccination. We report one case with invasive nonvaccine serotype 25 that presented with meningitis.
authors: Suleiman Al Alola, MD, Department of Pediatrics,, Infectious Disease Division,, King Abdulaziz Medical City,, PO Box 22490, Riyadh, 11426,, Saudi Arabia, alloaS@ngha.med.sa.
authors: Badria Rashid
authors: BR
authors: Al Waili
authors: Suleiman
authors: S
authors: Alola
authors: Esam
authors: E
authors: Albanyan
mesh_terms: D005260:Female; D006801:Humans; D008586:Meningitis, Pneumococcal / Q000382:microbiology*; D011008:Pneumococcal Infections / Q000382:microbiology* / Q000517:prevention & control; D022242:Pneumococcal Vaccines / Q000008:administration & dosage; D013296:Streptococcus pneumoniae / Q000302:isolation & purification*; D018074:Vaccines, Conjugate / Q000008:administration & dosage
chemical_list: C538862:13-valent pneumococcal vaccine; D022242:Pneumococcal Vaccines; D018074:Vaccines, Conjugate