title: Comparisons of serum total IgE, IgG, and IgG1 levels in patients with and without echinococcosis-induced anaphylactic shock.
abstract: We investigated serum total immunoglobulin E (IgE), IgG, and IgG1 levels in patients with and without echinococcosis-induced anaphylactic shock. This was a case-control study of 11 patients with echinococcosis-induced anaphylactic shock and 22 echinococcosis patients with cyst rupture but without anaphylactic shock. Blood was collected before surgery (T0), at the time of cyst rupture (T1), and shock (Tx), 1 h (T2), 1 day (T3), and 1 week (T4) after cyst rupture. Serum IgE, IgG, and IgG1 were determined by enzyme-linked immunosorbent assay. Serum IgE, IgG, and IgG1 levels were significantly higher in patients who developed anaphylactic shock at all time points. Increased pre-surgical IgG and IgG1 levels were identified to be a significant risk factors for developing anaphylactic shock. The results showed that a serum IgG concentration of 312.25 μg/mL could be used as a cut-off point to predict whether an echinococcosis patient would develop anaphylactic shock.
authors: Department of Pain Medicine, First Affiliated Hospital of Xinjiang Medical University, Urumqi, People's Republic of China. hanyuner1969@163.com
authors: Yimei
authors: Y
authors: Li
authors: Hong
authors: H
authors: Zheng
authors: Meilin
authors: M
authors: Gu
authors: Xinghua
authors: X
authors: Cao
authors: Hao
authors: H
authors: Wen
authors: Zaoling
authors: Z
authors: Liu
authors: Tao
authors: T
authors: Liu
mesh_terms: D000328:Adult; D000707:Anaphylaxis / Q000097:blood* / Q000209:etiology; D016022:Case-Control Studies; D004443:Echinococcosis / Q000097:blood* / Q000150:complications; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male
chemical_list: D007074:Immunoglobulin G; D007073:Immunoglobulin E