title: Hepatoprotective activity of Cyperus tegetum rhizome against paracetamol-induced liver damage in rats.
abstract: In present study the methanol extract of Cyperus tegetum rhizome (MECT) was evaluated for its effect on paracetamol-induced liver damage in Wistar rats. Serum biochemical parameters viz. serum glutamine oxaloacetate transaminase (SGOT), serum glutamine pyruvate transaminase (SGPT), serum alkaline phosphatase (ALP), total serum protein, total bilirubin content and liver biochemical parameters such as thiobarbituric acid reactive substances (TBARS) and reduced glutathione content were estimated. Biochemical and histopathological observations indicated that MECT had remarkable hepatoprotective effect against paracetamol-induced liver damage in rats.
authors: Jadavpur University.
authors: Pallab K
authors: PK
authors: Haldar
authors: Samit
authors: S
authors: Bera
authors: Siva P
authors: SP
authors: Panda
authors: Sanjib
authors: S
authors: Bhattacharya
authors: Nitai C
authors: NC
authors: Chaulya
authors: Arup
authors: A
authors: Mukherjee
mesh_terms: D000082:Acetaminophen / Q000633:toxicity; D018712:Analgesics, Non-Narcotic / Q000633:toxicity; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury / Q000517:prevention & control*; D029786:Cyperus; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000473:pathology; D008111:Liver Function Tests; D008297:Male; D000432:Methanol; D010936:Plant Extracts / Q000494:pharmacology*; D020011:Protective Agents / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D027343:Rhizome; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
chemical_list: D018712:Analgesics, Non-Narcotic; D010936:Plant Extracts; D020011:Protective Agents; D017392:Thiobarbituric Acid Reactive Substances; D000082:Acetaminophen; D000432:Methanol