title: Cu(II)-promoted transformations of α-thienylcarbinols into spirothienooxindoles: regioselective halogenation of dienyl sulfethers containing electron-rich aryl rings.
abstract: Under the promotion of Cu(II) salts, the α-thienylcarbinols with an N-phenyl carbonyl group at the other α-position are converted into three different ranges of spirothienooxindoles involving dearomatizing Friedel-Crafts reaction. In addition, the unprecedented regioselective CuX(2)-mediated C-H functionalization/halogenation of dienyl sulfether containing electron-rich aryl rings is presented.
authors: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong, 510640, China. blyin@scut.edu.cn
authors: Biaolin
authors: B
authors: Yin
authors: Li
authors: L
authors: Huang
authors: Xiaoyu
authors: X
authors: Zhang
authors: Fanghua
authors: F
authors: Ji
authors: Huanfeng
authors: H
authors: Jiang
mesh_terms: D003300:Copper / Q000737:chemistry*; D004583:Electrons; D004987:Ethers / Q000737:chemistry*; D054879:Halogenation; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D000432:Methanol / Q000031:analogs & derivatives / Q000737:chemistry*; D015394:Molecular Structure; D000078183:Oxindoles; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004987:Ethers; D007211:Indoles; D000078183:Oxindoles; D013141:Spiro Compounds; C022960:2-oxindole; D003300:Copper; D000432:Methanol