title: Palladium-catalyzed borylation of primary alkyl bromides.
abstract: A mild Pd-catalyzed process for the borylation of alkyl bromides has been developed using bis(pinacolato)diboron as a boron source. This process accommodates the use of a wide range of functional groups on the alkyl bromide substrate. Primary bromides react with complete selectivity in the presence of a secondary bromide. The generality of this approach is demonstrated by its extension to the use of alkyl iodides and alkyl tosylates, as well as borylation reactions employing bis(neopentyl glycolato)diboron as the boron source.
authors: Department of Chemistry, The City College of New York, 160 Convent Avenue, New York, New York 10031, USA.
authors: Amruta
authors: A
authors: Joshi-Pangu
authors: Xinghua
authors: X
authors: Ma
authors: Mohamed
authors: M
authors: Diane
authors: Sidra
authors: S
authors: Iqbal
authors: Robert J
authors: RJ
authors: Kribs
authors: Richard
authors: R
authors: Huang
authors: Chao-Yuan
authors: CY
authors: Wang
authors: Mark R
authors: MR
authors: Biscoe
mesh_terms: D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D001896:Boron Compounds; D006843:Hydrocarbons, Chlorinated; D010165:Palladium