title: The use of human acellular dermal matrix in the prevention of infra-auricular depressed deformities and Frey's syndrome following total parotidectomy.
abstract: BACKGROUND
  The aim of the study was to explore whether human acellular dermal matrix (ADM) implantation could prevent infra-auricular depressed deformities and Frey's syndrome following total parotidectomy.
  
  
  METHODS
  We analyzed 41 cases of total parotidectomy (control group) and 29 cases of simultaneous ADM implantation following total parotidectomy (ADM group) for infra-auricular depressed deformities and the presence of gustatory flushing or sweating. The follow-up periods ranged from 6 months to 7 years.
  
  
  RESULTS
  Facial contours and bilateral symmetry improved after surgery in the ADM group. In the control group, an infra-auricular depressed deformity was evident in all 41 cases. Frey's syndrome was recorded in 1 patient (3.4%) from the ADM group and 14 patients (34.1%) from the control group. No cases of immune rejection, infection, hematoma, or salivary fistula were observed in either group.
  
  
  CONCLUSIONS
  The use of ADM could reduce postoperative facial contour deformities and Frey's syndrome following total parotidectomy.
authors: Department of Oral & Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
authors: Wen
authors: W
authors: Luo
authors: Xiaohui
authors: X
authors: Zheng
authors: Lin
authors: L
authors: Chen
authors: Wei
authors: W
authors: Jing
authors: Wei
authors: W
authors: Tang
authors: Jie
authors: J
authors: Long
authors: Weidong
authors: W
authors: Tian
authors: Lei
authors: L
authors: Liu
mesh_terms: D062088:Acellular Dermis; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003094:Collagen; D005145:Face / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010306:Parotid Gland / Q000601:surgery*; D010307:Parotid Neoplasms / Q000601:surgery; D011183:Postoperative Complications / Q000517:prevention & control*; D017768:Skin, Artificial; D013547:Sweating, Gustatory / Q000517:prevention & control*; D055815:Young Adult
chemical_list: C440568:Alloderm; D003094:Collagen