title: Stereoselective intermolecular C-H amination reactions.
abstract: A novel chiral N-mesyloxycarbamate to perform rhodium-catalyzed stereoselective C-H amination reactions is reported. Chiral benzylic and propargylic amines are produced in good yields and selectivities using ethyl acetate as solvent. The corresponding free amines are easily obtained by cleavage of the chiral reagent, which could also be recovered.
authors: Département de chimie et Centre en chimie verte et catalyse, Université de Montréal, 2900 Boul. Edouard Montpetit, Montréal, Québec, Canada. helene.lebel@umontreal.ca
authors: Hélène
authors: H
authors: Lebel
authors: Carl
authors: C
authors: Trudel
authors: Cédric
authors: C
authors: Spitz
mesh_terms: D000085:Acetates / Q000737:chemistry; D000586:Amination; D000588:Amines / Q000737:chemistry*; D001596:Benzylamines / Q000737:chemistry; D002244:Carbon / Q000737:chemistry*; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry*; D010293:Pargyline / Q000031:analogs & derivatives / Q000737:chemistry; D011437:Propylamines / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000085:Acetates; D000588:Amines; D001596:Benzylamines; D011437:Propylamines; C009054:propargylamine; D002244:Carbon; C007650:ethyl acetate; D006859:Hydrogen; D010293:Pargyline; C030796:benzylamine; D012238:Rhodium