title: Utility of neuropsychological testing for guiding treatment decisions in paediatric multiple sclerosis.
abstract: In the past years, there has been growing awareness about childhood onset multiple sclerosis (MS) and the relevance of psychosocial aspects such as cognitive disturbances, fatigue and depression in this population. We describe a case of a 16-year-old patient with relapsing-remitting multiple sclerosis (RRMS) who presented at our clinic with severe fatigue symptoms and who underwent repeated neuropsychological examinations. A sudden significant slowing indicated a new relapse while neurological examination did not. This case highlights the high sensitivity and clinical relevance of neuropsychological testing in patients with juvenile MS even in the context of treatment decisions.
authors: Department of Cognitive Psychology and Methodology, University of Basel, Switzerland.
authors: Iris-Katharina
authors: IK
authors: Penner
authors: Martina
authors: M
authors: Hubacher
authors: Maria
authors: M
authors: Rasenack
authors: Till
authors: T
authors: Sprenger
authors: Peter
authors: P
authors: Weber
authors: Yvonne
authors: Y
authors: Naegelin
mesh_terms: D000293:Adolescent; D003072:Cognition Disorders / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000188:drug therapy / Q000523:psychology / Q000628:therapy*; D018696:Neuroprotective Agents / Q000627:therapeutic use; D009483:Neuropsychological Tests / Q000592:standards*; D012008:Recurrence; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D018696:Neuroprotective Agents