title: Recent advances in perioperative anesthetic management update in the perioperative support of patients with septic shock and the effect on outcomes.
abstract: Septic shock during the perioperative period imparts significant challenges for anesthetic management. There is increasing support for standardization of care using evidence-based, international consensus guidelines, such as the Surviving Sepsis Campaign. This review will highlight practices in the supportive management relevant to the perioperative care of patients with severe sepsis or septic shock and their effect on clinical outcomes. It will address the epidemiological data of sepsis, the diagnostic criteria, and the role of routine, goal-directed hemodynamic resuscitation. Furthermore, it will review other options for support, including antibiotics, intensive insulin therapy, and intensive care sedation in this high risk patient population.
authors: Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio, USA.
authors: Aaron
authors: A
authors: Douglas
authors: Ellen
authors: E
authors: Wurm
authors: Patrick
authors: P
authors: Pickett
authors: J Steven
authors: JS
authors: Hata
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000758:Anesthesia / Q000009:adverse effects / Q000592:standards; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003422:Critical Care / Q000592:standards; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D005440:Fluid Therapy; D006439:Hemodynamics; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D019990:Perioperative Care / Q000009:adverse effects / Q000379:methods* / Q000592:standards; D010952:Plasma Substitutes / Q000627:therapeutic use; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D012772:Shock, Septic / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D059039:Standard of Care; D016896:Treatment Outcome; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D005343:Fibrinolytic Agents; D006993:Hypnotics and Sedatives; D007004:Hypoglycemic Agents; D010952:Plasma Substitutes; D014662:Vasoconstrictor Agents