title: Primary sex headache in adolescents.
abstract: Primary headache associated with sexual activity is a rare headache disorder that has only been reported twice previously in adolescents. Although it can mimic life-threatening causes of thunderclap-onset headache, primary sex headache is benign, self-limited, and highly responsive to indomethacin. Given the sensitive nature of sexual development in adolescents, it is important that pediatric providers know when to ask about this symptom and how to proceed with diagnostics and therapy when it arises. We report 2 new adolescent cases and review the semiology, epidemiology, and treatment of primary sex headache.
authors: aDivision of Child NeurologyUniversity of California, San Francisco, California, 94115, USA. gelfanda@neuropeds.ucsf.edu
authors: Amy A
authors: AA
authors: Gelfand
authors: Peter J
authors: PJ
authors: Goadsby
mesh_terms: D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D002227:Carbazoles / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D020022:Genetic Predisposition to Disease; D051270:Headache Disorders, Primary / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008881:Migraine Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000235:genetics; D009460:Neurologic Examination; D009948:Orgasm; D010871:Pinealoma / Q000628:therapy; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D012075:Remission, Spontaneous; D017366:Serotonin Receptor Agonists / Q000627:therapeutic use; D014363:Tryptamines / Q000627:therapeutic use
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D002227:Carbazoles; D017366:Serotonin Receptor Agonists; D014363:Tryptamines; C108128:frovatriptan; D007213:Indomethacin