title: LC-MS/MS screen for xenobiotics and metabolites.
abstract: Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is now considered as a perfect complement to HPLC-DAD (diode array detection) and gas chromatography (GC)-MS for the general unknown screening of drugs and toxic compounds.Here we describe a procedure applied routinely in our laboratory for clinical and forensic applications using the QTRAP™ technology.
authors: Department of Pharmacology-Toxicology-Pharmacovigilance, Centre Hospitalier Universitaire (CHU) de Limoges, Limoges, France.
authors: François-Ludovic
authors: FL
authors: Sauvage
authors: Pierre
authors: P
authors: Marquet
mesh_terms: D002851:Chromatography, High Pressure Liquid; D006801:Humans; D052616:Solid Phase Extraction; D053719:Tandem Mass Spectrometry; D015262:Xenobiotics / Q000032:analysis* / Q000097:blood / Q000378:metabolism* / Q000652:urine
chemical_list: D015262:Xenobiotics