title: Indocyanine green encapsulated nanogels for hyaluronidase activatable and selective near infrared imaging of tumors and lymph nodes.
abstract: Indocyanine green (ICG) encapsulated hyaluronic acid (HA) nanogels were first studied for highly selective detection of specific cancers and lymph nodes via hyaluronidase sensitive switch-on of near infrared fluorescence as a long-lasting and stimuli-responsive imaging probe.
authors: BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 305-806, Republic of Korea.
authors: Hyejung
authors: H
authors: Mok
authors: Hyunkyung
authors: H
authors: Jeong
authors: Sun-Jung
authors: SJ
authors: Kim
authors: Bong Hyun
authors: BH
authors: Chung
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D003692:Delayed-Action Preparations / Q000737:chemistry / Q000378:metabolism*; D003952:Diagnostic Imaging / Q000379:methods; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000008:administration & dosage / Q000737:chemistry; D005782:Gels / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D006820:Hyaluronic Acid / Q000737:chemistry / Q000378:metabolism*; D006821:Hyaluronoglucosaminidase / Q000737:chemistry / Q000378:metabolism*; D007208:Indocyanine Green / Q000008:administration & dosage / Q000737:chemistry; D008198:Lymph Nodes / Q000201:enzymology / Q000473:pathology*; D051379:Mice; D009369:Neoplasms / Q000175:diagnosis* / Q000201:enzymology
chemical_list: D003692:Delayed-Action Preparations; D005456:Fluorescent Dyes; D005782:Gels; D006820:Hyaluronic Acid; D006821:Hyaluronoglucosaminidase; D007208:Indocyanine Green