title: [Xenon anaesthesia--clinical characteristics, benefits and disadvantages and fields of application].
abstract: The noble gas xenon provides many characteristics of the 'ideal anaesthetic agent'. Xenon offers outstanding haemodynamic stability and rapid emergence from anaesthesia without relevant side effects or toxity. The major limitation for its application in clinical routine is the high price. Recent studies demonstrated additional protective effects against ischaemic injury in particular for the heart and the brain. Therefore, xenon may be beneficial in a subset of high risk patients or operations and may become a meaningful alternative to other anaesthetics in this population.
authors: Klinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Germany. jan.hoecker@uksh.de
authors: Jan
authors: J
authors: Höcker
authors: Matthias
authors: M
authors: Grünewald
authors: Berthold
authors: B
authors: Bein
mesh_terms: D000769:Anesthesia, Inhalation; D018685:Anesthetics, Inhalation / Q000009:adverse effects / Q000737:chemistry / Q000266:history / Q000494:pharmacology; D006348:Cardiac Surgical Procedures; D002318:Cardiovascular Diseases / Q000150:complications; D003072:Cognition Disorders / Q000209:etiology / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D005971:Glutamates / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D018696:Neuroprotective Agents / Q000494:pharmacology; D011183:Postoperative Complications / Q000453:epidemiology / Q000523:psychology; D015221:Potassium Channels / Q000187:drug effects / Q000378:metabolism; D012306:Risk; D015398:Signal Transduction / Q000187:drug effects; D014978:Xenon / Q000009:adverse effects / Q000737:chemistry / Q000266:history / Q000494:pharmacology
chemical_list: D018685:Anesthetics, Inhalation; D005971:Glutamates; D018696:Neuroprotective Agents; D015221:Potassium Channels; D014978:Xenon