title: Lack of Cry1Fa binding to the midgut brush border membrane in a resistant colony of Plutella xylostella moths with a mutation in the ABCC2 locus.
abstract: Previous studies reported "mode 1" Bacillus thuringiensis resistance in a colony of diamondback moths (NO-QA), and recently, this resistance has been mapped to an ABC transporter (ABCC2) locus. We report the lack of binding of Cry1Fa to insects derived from this colony and compare our data with those from other insects with ABCC2-associated resistance.
authors: Departamento de Genética, Facultad de CC. Biológicas, Universidad de Valencia, Burjassot, Valencia, Spain.
authors: Patricia
authors: P
authors: Hernández-Martínez
authors: Carmen Sara
authors: CS
authors: Hernández-Rodríguez
authors: Vidisha
authors: V
authors: Krishnan
authors: Neil
authors: N
authors: Crickmore
authors: Baltasar
authors: B
authors: Escriche
authors: Juan
authors: J
authors: Ferré
mesh_terms: D000818:Animals; D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins; D004351:Drug Resistance; D004731:Endotoxins; D006460:Hemolysin Proteins; D007915:Lepidoptera / Q000187:drug effects* / Q000235:genetics; D008871:Microvilli / Q000187:drug effects / Q000235:genetics; D000089762:Multidrug Resistance-Associated Protein 2; D027425:ATP-Binding Cassette, Sub-Family C Proteins / Q000235:genetics*; D009154:Mutation; D011485:Protein Binding
chemical_list: D000083722:Bacillus thuringiensis Toxins; D001426:Bacterial Proteins; D004731:Endotoxins; D006460:Hemolysin Proteins; D000089762:Multidrug Resistance-Associated Protein 2; D027425:ATP-Binding Cassette, Sub-Family C Proteins; C030956:insecticidal crystal protein, Bacillus Thuringiensis