title: The Mayo prosthetic joint infection risk score: implication for surgical site infection reporting and risk stratification.
abstract: OBJECTIVE
  The goal of this study was to develop a prognostic scoring system for the development of prosthetic joint infection (PJI) that could risk-stratify patients undergoing total hip (THA) or total knee (TKA) arthroplasties.
  
  
  METHODS
  Previously reported case-control study.
  
  
  METHODS
  Tertiary referral care setting from 2001 through 2006.
  
  
  METHODS
  A derivation data set of 339 cases and 339 controls was used to develop 2 scores. A baseline score and a 1-month-postsurgery risk score were computed as a function of the relative contributions of risk factors for each model. Points were assigned for the presence of each factor and then summed to get a subject's risk score.
  
  
  RESULTS
  The following risk factors were detected from multivariable modeling and incorporated into the baseline Mayo PJI risk score: body mass index, prior other operation on the index joint, prior arthroplasty, immunosuppression, ASA score, and procedure duration (c index, 0.722). The 1-month-postsurgery risk score contained the same variables in addition to postoperative wound drainage (c index, 0.716).
  
  
  CONCLUSIONS
  The baseline score might help with risk stratification in relation to public reporting and reimbursement as well as targeted prevention strategies in patients undergoing THA or TKA. The application of the 1-month-postsurgery PJI risk score to patients undergoing THA or TKA might benefit those undergoing workup for PJI.
authors: Department of Medicine, Division of Infectious Diseases, Section of Orthopedic Infections, Mayo Clinic, Rochester, Minnesota 55905, USA. berbari.elie@mayo.edu
authors: Elie F
authors: EF
authors: Berbari
authors: Douglas R
authors: DR
authors: Osmon
authors: Brian
authors: B
authors: Lahr
authors: Jeanette E
authors: JE
authors: Eckel-Passow
authors: Geoffrey
authors: G
authors: Tsaras
authors: Arlen D
authors: AD
authors: Hanssen
authors: Tad
authors: T
authors: Mabry
authors: James
authors: J
authors: Steckelberg
authors: Rodney
authors: R
authors: Thompson
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D015992:Body Mass Index; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects; D008297:Male; D015999:Multivariate Analysis; D012372:ROC Curve; D012086:Reoperation / Q000009:adverse effects; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000517:prevention & control; D013997:Time Factors