title: Gingival overgrowth in a dog that received long-term cyclosporine for immune-mediated hemolytic anemia.
abstract: Gingival mass lesions developed when cyclosporine was administered for 600 days to a female, 7-year-old, longhaired dachshund diagnosed with intractable immune-mediated hemolytic anemia (IMHA). Histopathology indicated hyperplastic suppurative gingivitis. As the anemia improved, the dosage of cyclosporine A (CsA) was markedly decreased, and the mass lesions decreased in size and disappeared, thus suggesting that the mass lesions were an adverse reaction to CsA.
authors: Veterinary Teaching Hospital, Azabu University, 1-17-71 Fuchinobe, Chuo, Sagamihara, Kanagawa 252-2501, Japan. namikawa@azabu-u.ac.jp
authors: Kazuhiko
authors: K
authors: Namikawa
authors: Takuya
authors: T
authors: Maruo
authors: Mayumi
authors: M
authors: Honda
authors: Hitomi
authors: H
authors: Hirata
authors: Jonathan
authors: J
authors: Lynch
authors: Hiroo
authors: H
authors: Madarame
mesh_terms: D000743:Anemia, Hemolytic / Q000188:drug therapy / Q000662:veterinary; D000818:Animals; D016572:Cyclosporine / Q000009:adverse effects* / Q000627:therapeutic use; D004283:Dog Diseases / Q000139:chemically induced*; D004285:Dogs; D005260:Female; D005885:Gingival Hyperplasia / Q000139:chemically induced / Q000662:veterinary*; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine