title: [Cutaneous drug eruption at hospital in Bamako].
abstract: BACKGROUND
  The incidences of cutaneous drug eruption constitute a real public health problem.
  
  
  OBJECTIVE
  The aim of this study was to describe the cutaneous drug eruption in Gabriel Touré Hospital in Bamako.
  
  
  METHODS
  This is a prospective longitudinal study from 1 July 2005 to August 31, 2006. The study included patients with a lesion cutaneous Contemporary taking medication, without other cause and consent.
  
  
  RESULTS
  We included 61 cases of toxdermies. The mean age was 28 ± 14.8 years with extremes of 18 and 77 years. The sex ratio was 2.4 for women. Self-medication was most often found in 51% of cases. The fixed drug eruption (EPF) with 26 cases (30.6%); acne with 23 cases (27%), erythema multiforme with 14 cases (16.5%) are the predominant manifestations toxidermy. The causative drugs are molecules with 12.6% with analgesics, NSAIDs with 12.6%, 13.6% with ARVs; sulfonamides with 9.5% with 7.4% beta-lactam; anticonvulsants with 5.2%. The therapeutic management was simple for minor forms. Severe forms have been hospitalized and often the help of intensive care and ophthalmology. Mortality was 2.3%.
  
  
  CONCLUSIONS
  The toxidermy exist in Mali with a frequency more and more increasing. We recommend the systematic toxidermy consultations especially among HIV patients in Mali.
authors: Service de dermatologie, CHU-Gabriel Toure Bamako, Mali.
authors: H D
authors: HD
authors: Konaré
authors: I A
authors: IA
authors: Cissé
authors: A A
authors: AA
authors: Oumar
authors: S
authors: S
authors: Idrissa
authors: S
authors: S
authors: Maiga
authors: S
authors: S
authors: Dao
authors: A
authors: A
authors: Rhaly
authors: A
authors: A
authors: Tounkara
mesh_terms: D000152:Acne Vulgaris / Q000139:chemically induced / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D000927:Anticonvulsants / Q000009:adverse effects; D003875:Drug Eruptions / Q000453:epidemiology* / Q000209:etiology; D004892:Erythema Multiforme / Q000453:epidemiology; D005260:Female; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008302:Mali / Q000453:epidemiology; D008875:Middle Aged; D009017:Morbidity / Q000639:trends; D011446:Prospective Studies; D012651:Self Medication / Q000009:adverse effects; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000927:Anticonvulsants