title: Interleukin 21 impairs tumor immunosurveillance of colitis-associated colorectal cancer.
abstract: The pathogenesis of colitis-associated colorectal cancer is strongly influenced by immune cells, cytokines and other immune mediators present in the inflamed colon. Current research has emerged that T helper cell associated cytokines play a prominent role in tumor growth. In our recent manuscript we have revealed that the Th17 associated cytokine IL-21 prominently influences tumor development and immunosurveillance of colitis-associated colorectal cancer.
authors: Laboratory of Chronic Immunopathology; Department of Surgery; University Medical Center Regensburg; Regensburg, Germany.
authors: Rebecca
authors: R
authors: Kesselring
authors: Dominik
authors: D
authors: Jauch
authors: Stefan
authors: S
authors: Fichtner-Feigl