title: [Drinking-water type fluorosis treated with acupuncture of reinforcing kidney and activating spleen: a randomized controlled trial].
abstract: OBJECTIVE
  To observe the impacts of acupuncture of reinforcing kidney and activating spleen on the excretion of urinary fluoride and pain of the patients with drinking-water type fluorosis.
  
  
  METHODS
  The randomized controlled and single-blind trial was adopted. Seventy-two cases were randomized into an observation group and a control group, 36 cases in each one. In the observation group, acupuncture was applied at Pishu (BL 20), Shenshu (BL 23), Guanyuan (CV 4), Zusanli (ST 36), etc. , three treatments a week. In the control group, the Calcium Carbonate D3 tablets were prescribed for oral administration, 600 mg each time, twice a day. The duration of treatment was 2 months. The changes of the content of urinary fluoride and pain score (by VAS) before and after treatment between two groups were compared.
  
  
  RESULTS
  The urinary fluoride excretion was increased obviously after treatment in the observation group (P < 0.01), which was superior apparently to that in the control group [(11.06 +/- 4.54) mg/L vs. (8.30 +/- 4.14) mg/L, P < 0.05]. After treatment, VAS score was reduced significantly in either group (both P < 0.01). The result in the observation group was lower remarkably than that in the control group (1.93 +/- 1.30 vs. 3.47 +/- 2.29, P < 0.01).
  
  
  CONCLUSIONS
  Acupuncture achieves the significant efficacy on the promotion of urinary fluoride excretion and pain relieving of the patients with drinking-water type fluorosis in light of reinforcing kidney and activating spleen, which is superior to the oral administration of the calcium carbonate D3 tablets.
authors: Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Acupuncture and Moxibustion Hospital, China Academy of Chinese Medical Sciences, Beijing, China. yijingguaxian@yahoo.com.cn
authors: Xiao-guang
authors: XG
authors: Zhao
authors: Zhong-chao
authors: ZC
authors: Wu
authors: Zhong-jie
authors: ZJ
authors: Chen
authors: Jing-jing
authors: JJ
authors: Wang
authors: Jin-cao
authors: JC
authors: Zhou
authors: Li
authors: L
authors: Pang
authors: Yue
authors: Y
authors: Jiao
authors: Jing
authors: J
authors: Hu
authors: Cheng-bin
authors: CB
authors: Cui
mesh_terms: D015670:Acupuncture Therapy; D000328:Adult; D000368:Aged; D060766:Drinking Water / Q000009:adverse effects* / Q000032:analysis; D005260:Female; D005459:Fluorides / Q000633:toxicity / Q000652:urine; D009050:Fluorosis, Dental / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D013154:Spleen / Q000503:physiopathology*; D014554:Urination
chemical_list: D060766:Drinking Water; D005459:Fluorides