title: Evaluation of BACTEC MGIT 960 system for the second-line drugs susceptibility testing of Mycobacterium tuberculosis in China.
abstract: When the performance of the BACTEC MGIT 960 system was evaluated with the traditional proportion method (PM) on 321 clinical isolates of Mycobacterium tuberculosis from China, concordance values were 98.44% capreomycin, 98.75% kanamycin, 98.75% ofloxacin and 94.08% ethionamide. The turnaround time with BACTEC MGIT 960 system (7.5±1.8 days) was significantly shorter than with PM (28 days or 42 days). Therefore, the BACTEC MGIT 960 system was a reliable and rapid method for second-line drug susceptibility testing of TB in China.
authors: National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention/State Key Laboratory for Infectious Disease Prevention and Control/National Reference Laboratory of tuberculosis, Beijing 102206, China.
authors: Li-li
authors: LL
authors: Zhao
authors: Qiang
authors: Q
authors: Xia
authors: Nan
authors: N
authors: Lin
authors: Binbin
authors: B
authors: Liu
authors: Xiu-qin
authors: XQ
authors: Zhao
authors: Zhiguang
authors: Z
authors: Liu
authors: Kang-lin
authors: KL
authors: Wan
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology*; D002681:China; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000302:isolation & purification; D013997:Time Factors; D014376:Tuberculosis / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents