title: Spinal cord ischemia after endovascular aortic repair versus open surgical repair for descending thoracic and thoracoabdominal aortic aneurism.
abstract: OBJECTIVE
  Thoracic endovascular aortic repair (TEVAR) an emerging less invasive alternative to surgery, is now being increasingly employed, but spinal cord ischemia (SCI) is still a threat with this procedure. Delayed paraplegia has been frequently observed after TEVAR, suggesting there may be different courses of SCI between TEVAR and the conventional open surgical repair (OSR) of thoracic and thoracoabdominal aneurysms. Therefore, we conducted a study to investigate the risk factors for and the course of SCI after TEVAR and OSR.
  
  
  METHODS
  We studied a series of 414 OSR and 94 TEVAR patients prospectively. Postoperative motor function, sensory disturbance, and bladder disturbance were assessed daily to evaluate the course of SCI. Previously reported risk factors for SCI were investigated.
  
  
  RESULTS
  Spinal cord ischemia occurred in 6 patients (6.4 %) in the TEVAR group, and in 18 patients (4.3 %) in the OSR group, resulting in no significant difference (p = 0.401). A greater percentage of patients (n = 4, 66.7 %) with SCI in the TEVAR group had a delayed onset, compared with 16.7 % (n = 3) in the OSR group (p = 0.038). The rate of recovery of walking function after SCI and the incidence of sensory disturbance and bladder dysfunction was similar in the two groups. Multivariate analysis demonstrated that, in the TEVAR group, the stent length of aortic coverage was a significant risk factor for SCI.
  
  
  CONCLUSIONS
  The incidence of SCI was similar in the OSR and TEVAR groups, but delayed SCI occurred more frequently in the TEVAR group. Except for the delayed onset of SCI, SCI showed a similar course of recovery in the two groups.
authors: Department of Anesthesiology, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka, 565-8565, Japan.
authors: Takuma
authors: T
authors: Maeda
authors: Kenji
authors: K
authors: Yoshitani
authors: Shunsuke
authors: S
authors: Sato
authors: Hitoshi
authors: H
authors: Matsuda
authors: Yuzuru
authors: Y
authors: Inatomi
authors: Yukihiko
authors: Y
authors: Tomita
authors: Hitoshi
authors: H
authors: Ogino
authors: Yoshihiko
authors: Y
authors: Ohnishi
mesh_terms: D000368:Aged; D017545:Aortic Aneurysm, Thoracic / Q000601:surgery*; D002555:Cerebrospinal Fluid; D015331:Cohort Studies; D004322:Drainage; D057510:Endovascular Procedures / Q000009:adverse effects*; D019054:Evoked Potentials, Motor / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000209:etiology / Q000503:physiopathology; D011183:Postoperative Complications / Q000503:physiopathology / Q000628:therapy*; D011446:Prospective Studies; D012307:Risk Factors; D020760:Spinal Cord Ischemia / Q000209:etiology* / Q000628:therapy*; D015607:Stents; D001745:Urinary Bladder Diseases / Q000453:epidemiology / Q000209:etiology