title: Polyostotic Paget's disease.
abstract: Paget's disease of bone is a common metabolic bone disease in most of the European countries. The disease has distinct geographical distribution being rare in Asia. We report Paget's disease in a 70 years old Pakistani male who presented with history of pain in right leg with difficulty in walking for the last 5 months. Plain X-ray raised suspicion of Paget's disease of bone. Technetium-99m MDP bone scan showed involvement of multiple bones. Bone biopsy confirmed the diagnosis. This case illustrates that Paget's disease of bone does exist in Pakistan.
authors: Department of Nuclear Medicine, Nuclear Medicine Oncology and Radiotherapy Institute (NORI), Islamabad, Pakistan. drsadafpk@hotmail.com
authors: Sadaf Tufail
authors: ST
authors: Butt
authors: Shazia
authors: S
authors: Fatima
authors: Rafi
authors: R
authors: Butt
authors: Wajiha
authors: W
authors: Nasir
authors: Ghazal
authors: G
authors: Jameel
authors: Javaid
authors: J
authors: Irfan
mesh_terms: D000368:Aged; D019386:Alendronate / Q000627:therapeutic use; D000469:Alkaline Phosphatase / Q000097:blood; D001706:Biopsy; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010001:Osteitis Deformans / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000473:pathology; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate; D013977:Tibia / Q000000981:diagnostic imaging* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D050071:Bone Density Conservation Agents; D019275:Radiopharmaceuticals; D000469:Alkaline Phosphatase; D019386:Alendronate; D013669:Technetium Tc 99m Medronate