title: Seroprevalence of Entamoeba histolytica infection in China.
abstract: The seroprevalence of Entamoeba histolytica infection in the residents of seven provinces in China was examined by using an enzyme-linked immunosorbent assay with a crude antigen and a recombinant surface antigen, C-Igl, of the parasites. A total of 1,312 serum samples were investigated. The positivity rates for these two antigens were 11.05% and 6.25%, respectively. There was no significant difference in the seropositivity to E. histolytica between men and women. We used a logistic regression model and maximal-likelihood methods to estimate the prevalence of E. histolytica infection from sequential serologic data. Seropositivity in Sichuan, Guizhou, and Sinkiang Provinces was higher than that in Beijing, Shanghai, and Qinghai Provinces. The present study provides an overview of seropositivity to E. histolytica infection in seven provinces in China and use the logistic regression model estimation method to achieve a more accurate measure of amebiasis prevalence.
authors: Department of Microbiology and Parasitology, Shanghai Medical College, Fudan University, Shanghai, China. scobin3@gmail.com
authors: Bin
authors: B
authors: Yang
authors: Yingdan
authors: Y
authors: Chen
authors: Liang
authors: L
authors: Wu
authors: Longqi
authors: L
authors: Xu
authors: Hiroshi
authors: H
authors: Tachibana
authors: Xunjia
authors: X
authors: Cheng
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000953:Antigens, Protozoan / Q000276:immunology; D001483:Base Sequence; D002648:Child; D002681:China / Q000453:epidemiology; D017931:DNA Primers; D004748:Entamoeba histolytica / Q000276:immunology / Q000302:isolation & purification*; D004749:Entamoebiasis / Q000453:epidemiology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D000953:Antigens, Protozoan; D017931:DNA Primers