title: Molecular typing of Mycobacterium abscessus based on tandem-repeat polymorphism.
abstract: A variable-number tandem-repeat (VNTR) typing assay for the differentiation of Mycobacterium abscessus strains was developed. This assay showed complete reproducibility, locus stability, and a discriminatory power (Hunter-Gaston discriminatory index [HGDI] of 0.9563) that is superior to that of multilocus sequencing. It is a promising tool for the investigation of Mycobacterium abscessus epidemiology and nosocomial outbreaks.
authors: Department of Medical Microbiology, University of Malaya, Kuala Lumpur, Malaysia.
authors: Y L
authors: YL
authors: Wong
authors: C S
authors: CS
authors: Ong
authors: Y F
authors: YF
authors: Ngeow
mesh_terms: D004269:DNA, Bacterial / Q000235:genetics; D006801:Humans; D018598:Minisatellite Repeats; D017720:Molecular Epidemiology / Q000379:methods; D058889:Molecular Typing / Q000379:methods*; D009161:Mycobacterium / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D009165:Mycobacterium Infections, Nontuberculous / Q000382:microbiology; D011110:Polymorphism, Genetic; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D004269:DNA, Bacterial