title: [Significance of re-evaluation and development of Chinese herbal drugs].
abstract: The research of new herbal drugs involves in new herbal drugs development and renew the old drugs. It is necessary to research new herbal drugs based on the theory of traditional Chinese medicine (TCM). The current development of famous TCM focuses on the manufacture process, quality control standards, material basis and clinical research. But system management of security evaluation is deficient, the relevant system for the safety assessment TCM has not been established. The causes of security problems, security risks, target organ of toxicity, weak link of safety evaluation, and ideas of safety evaluation are discussed in this paper. The toxicology research of chinese herbal drugs is necessary based on standard of good laboratory practices (GLP), the characteristic of Chinese herbal drugs is necessary to be fully integrated into safety evaluation. The safety of new drug research is necessary to be integrated throughout the entire process. Famous Chinese medicine safety research must be paid more attention in the future.
authors: Beijing Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China. gaoyue@nic.bmi.ac.cn
authors: Yue
authors: Y
authors: Gao
authors: Zengchun
authors: Z
authors: Ma
authors: Boli
authors: B
authors: Zhang
mesh_terms: D002681:China; D004358:Drug Therapy; D004365:Drugs, Chinese Herbal / Q000009:adverse effects / Q000592:standards* / Q000627:therapeutic use; D006801:Humans; D008516:Medicine, Chinese Traditional / Q000592:standards*; D011786:Quality Control
chemical_list: D004365:Drugs, Chinese Herbal