title: Comparison of various methods for quantification of apparent diffusion coefficient of head and neck lesions with HASTE diffusion-weighted MR imaging.
abstract: OBJECTIVE
  The purposes of this retrospective study were to compare various methods of apparent diffusion coefficient (ADC) measurement for head and neck lesions in half-Fourier single-shot turbo spin-echo (HASTE) diffusion-weighted imaging (DWI) and determine the threshold ADC value for predicting malignancy.
  
  
  METHODS
  HASTE DW images of 46 lesions (10 cysts, 14 benign tumors, and 22 malignant tumors) were studied retrospectively. The ADC values were compared among the 0-1000 method, 500-1000 method, and weighted linear regression (WLR) fit.
  
  
  RESULTS
  The highest overall accuracies of 83.3%, 86.1%, and 88.9% were obtained when ADC values of 1.24 × 10(-3) mm(2)/s (0-1000 method), 0.98 × 10(-3) mm(2)/s (500-1000 method), and 1.23 × 10(-3) mm(2)/s (WLR fit), respectively, were used for the threshold.
  
  
  CONCLUSIONS
  The present results indicate that ADC measurement with HASTE DWI is useful in predicting malignancy of head and neck lesions.
authors: Department of Oral and Maxillofacial Radiology, Tokyo Dental College, Chiba, Japan. sakamotojun@tdc.ac.jp
authors: Junichiro
authors: J
authors: Sakamoto
authors: Yoshinori
authors: Y
authors: Sasaki
authors: Mika
authors: M
authors: Otonari-Yamamoto
authors: Tsukasa
authors: T
authors: Sano
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D003560:Cysts / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D017352:Echo-Planar Imaging / Q000379:methods; D005260:Female; D005583:Fourier Analysis; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D012372:ROC Curve; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D055815:Young Adult