title: [UPOINT: a novel phenotypic classification system for chronic prostatitis/chronic pelvic pain syndrome].
abstract: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common condition obsessing urologists and patients. It is also known as a heterogeneous syndrome, with varied etiologies, progression courses and responses to treatment. Based on the deeper insights into its pathogenesis and re-evaluation of its clinical trials, a novel phenotypic classification system UPOINT has been developed, which clinically classifies CP/CPPS patients into six domains: urinary (U), psychosocial (P), organ-specific (O), infection (I) , neurologic/systemic (N) and tenderness of pelvic floor skeletal muscles (T), and directs individualized and multimodal therapeutic approaches to CP/CPPS. This review systematically summarizes the theoretical foundation, clinical characteristics of UPOINT and treatment strategies based on the UPOINT phenotypic classification system.
authors: Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.
authors: Long-Fei
authors: LF
authors: Liu
authors: Long
authors: L
authors: Wang
authors: Te-Fei
authors: TF
authors: Lu
authors: Lin
authors: L
authors: Qi
authors: Xiong-Bing
authors: XB
authors: Zu
mesh_terms: D002908:Chronic Disease; D006801:Humans; D008297:Male; D017699:Pelvic Pain / Q000145:classification* / Q000175:diagnosis / Q000628:therapy; D010641:Phenotype; D011472:Prostatitis / Q000145:classification* / Q000175:diagnosis / Q000628:therapy; D012720:Severity of Illness Index