title: The Paleozoic origin of enzymatic lignin decomposition reconstructed from 31 fungal genomes.
abstract: Wood is a major pool of organic carbon that is highly resistant to decay, owing largely to the presence of lignin. The only organisms capable of substantial lignin decay are white rot fungi in the Agaricomycetes, which also contains non-lignin-degrading brown rot and ectomycorrhizal species. Comparative analyses of 31 fungal genomes (12 generated for this study) suggest that lignin-degrading peroxidases expanded in the lineage leading to the ancestor of the Agaricomycetes, which is reconstructed as a white rot species, and then contracted in parallel lineages leading to brown rot and mycorrhizal species. Molecular clock analyses suggest that the origin of lignin degradation might have coincided with the sharp decrease in the rate of organic carbon burial around the end of the Carboniferous period.
authors: Biology Department, Clark University, Worcester, MA 01610, USA.
authors: Dimitrios
authors: D
authors: Floudas
authors: Manfred
authors: M
authors: Binder
authors: Robert
authors: R
authors: Riley
authors: Kerrie
authors: K
authors: Barry
authors: Robert A
authors: RA
authors: Blanchette
authors: Bernard
authors: B
authors: Henrissat
authors: Angel T
authors: AT
authors: Martínez
authors: Robert
authors: R
authors: Otillar
authors: Joseph W
authors: JW
authors: Spatafora
authors: Jagjit S
authors: JS
authors: Yadav
authors: Andrea
authors: A
authors: Aerts
authors: Isabelle
authors: I
authors: Benoit
authors: Alex
authors: A
authors: Boyd
authors: Alexis
authors: A
authors: Carlson
authors: Alex
authors: A
authors: Copeland
authors: Pedro M
authors: PM
authors: Coutinho
authors: Ronald P
authors: RP
authors: de Vries
authors: Patricia
authors: P
authors: Ferreira
authors: Keisha
authors: K
authors: Findley
authors: Brian
authors: B
authors: Foster
authors: Jill
authors: J
authors: Gaskell
authors: Dylan
authors: D
authors: Glotzer
authors: Paweł
authors: P
authors: Górecki
authors: Joseph
authors: J
authors: Heitman
authors: Cedar
authors: C
authors: Hesse
authors: Chiaki
authors: C
authors: Hori
authors: Kiyohiko
authors: K
authors: Igarashi
authors: Joel A
authors: JA
authors: Jurgens
authors: Nathan
authors: N
authors: Kallen
authors: Phil
authors: P
authors: Kersten
authors: Annegret
authors: A
authors: Kohler
authors: Ursula
authors: U
authors: Kües
authors: T K Arun
authors: TK
authors: Kumar
authors: Alan
authors: A
authors: Kuo
authors: Kurt
authors: K
authors: LaButti
authors: Luis F
authors: LF
authors: Larrondo
authors: Erika
authors: E
authors: Lindquist
authors: Albee
authors: A
authors: Ling
authors: Vincent
authors: V
authors: Lombard
authors: Susan
authors: S
authors: Lucas
authors: Taina
authors: T
authors: Lundell
authors: Rachael
authors: R
authors: Martin
authors: David J
authors: DJ
authors: McLaughlin
authors: Ingo
authors: I
authors: Morgenstern
authors: Emanuelle
authors: E
authors: Morin
authors: Claude
authors: C
authors: Murat
authors: Laszlo G
authors: LG
authors: Nagy
authors: Matt
authors: M
authors: Nolan
authors: Robin A
authors: RA
authors: Ohm
authors: Aleksandrina
authors: A
authors: Patyshakuliyeva
authors: Antonis
authors: A
authors: Rokas
authors: Francisco J
authors: FJ
authors: Ruiz-Dueñas
authors: Grzegorz
authors: G
authors: Sabat
authors: Asaf
authors: A
authors: Salamov
authors: Masahiro
authors: M
authors: Samejima
authors: Jeremy
authors: J
authors: Schmutz
authors: Jason C
authors: JC
authors: Slot
authors: Franz
authors: F
authors: St John
authors: Jan
authors: J
authors: Stenlid
authors: Hui
authors: H
authors: Sun
authors: Sheng
authors: S
authors: Sun
authors: Khajamohiddin
authors: K
authors: Syed
authors: Adrian
authors: A
authors: Tsang
authors: Ad
authors: A
authors: Wiebenga
authors: Darcy
authors: D
authors: Young
authors: Antonio
authors: A
authors: Pisabarro
authors: Daniel C
authors: DC
authors: Eastwood
authors: Francis
authors: F
authors: Martin
authors: Dan
authors: D
authors: Cullen
authors: Igor V
authors: IV
authors: Grigoriev
authors: David S
authors: DS
authors: Hibbett
mesh_terms: D001487:Basidiomycota / Q000145:classification / Q000201:enzymology* / Q000235:genetics*; D001499:Bayes Theorem; D019143:Evolution, Molecular; D016681:Genome, Fungal; D007211:Indoles; D008031:Lignin / Q000378:metabolism*; D010544:Peroxidases / Q000235:genetics* / Q000378:metabolism; D014934:Wood / Q000378:metabolism
chemical_list: D007211:Indoles; C016060:phyriaviolin; D008031:Lignin; D010544:Peroxidases