title: Lipoprotein status among urban populations in Bangladesh.
abstract: OBJECTIVE
  Serum lipoprotein is the most important predictor for microvascular diseases, and may be influenced by rapid urbanization. Currently available data are limited, particularly regarding age-specific lipoprotein status in urban Bangladeshi populations.
  
  
  METHODS
  Blood lipoprotein levels of 51,353 male and female individuals primarily residing in urban Bangladesh were analyzed. De-identified data (collected between January 2005 and December 2011) were extracted from the Clinical Biochemistry Laboratory Data Archive of International Centre for Diarrheal Disease Research, Bangladesh (icddr,b). For analyses, six age categories were created: (i) <20 years, n = 481; (ii) 20-29 years, n = 1602; (iii) 30-39 years, n = 7272; (iv) 40-49 years, n = 13,582; (v) 50-59 years, n = 15,890; and (vi) 60 years and more, n = 12,526.
  
  
  RESULTS
  Mean serum levels of TC, LDL, TG, LDL:HDL and TC:HDL were significantly higher among adults 30-39 years old compared to other age groups, regardless of sex. The proportion of high TC and LDL from 2005 to 2011 among individuals aged 30-39 years old varied widely (p < 0.01 for trend and all pairwise tests).
  
  
  CONCLUSIONS
  30-39 years old individuals had higher concentration of lipoprotein, which increases microvascular disease risk. Further population-based studies are needed to validate our observations in rural areas of Bangladesh.
authors: International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Bangladesh.
authors: Sumon Kumar
authors: SK
authors: Das
authors: Abu Syed
authors: AS
authors: Golam Faruque
authors: Ashish Kumar
authors: AK
authors: Chowdhury
authors: Mohammod Jobayer
authors: MJ
authors: Chisti
authors: Mohammad Anowar
authors: MA
authors: Hossain
authors: Mohammed Abdus
authors: MA
authors: Salam
authors: Tahmeed
authors: T
authors: Ahmed
authors: Abdullah
authors: A
authors: Al Mamun
mesh_terms: D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000704:Analysis of Variance; D001459:Bangladesh / Q000453:epidemiology; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012111:Residence Characteristics; D018570:Risk Assessment; D012307:Risk Factors; D017678:Sex Distribution; D012737:Sex Factors; D015854:Up-Regulation; D014504:Urban Health; D014652:Vascular Diseases / Q000097:blood / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D015415:Biomarkers; D008074:Lipoproteins