title: Immediate cardiac arrest after neostigmine administration.
abstract: Many drugs used in anaesthesia have some potential fatal consequences; for example complete heart block and Q-Tc interval prolongation. Since the parasympathetic system in children is not fully developed, electrical transmission of the heart is not stable. Neostigmine is used in order to reverse neuromuscular block but it may also lead to prolongation of Q-Tc interval. We present a case of an 18-month-old male patient weighing 12kg subjected to a surgical operation because of congenital glaucoma. In order to reverse neuromuscular block at the end of operation, atropine and neostigmine were injected intravenously. However, cardiac arrest developed immediately after administration.
authors: Dicle University Medical School, Department of Anesthesiology and Reanimasyon, Diyarbakir, Turkey. adnantufek@hotmail.com
authors: Adnan
authors: A
authors: Tüfek
authors: Besir
authors: B
authors: Yildirim
authors: Orhan
authors: O
authors: Tokgöz
authors: Haktan
authors: H
authors: Karaman
authors: Feyzi
authors: F
authors: Celik
authors: Ilker Ongüç
authors: IO
authors: Aycan
mesh_terms: D004562:Electrocardiography; D005901:Glaucoma / Q000151:congenital* / Q000601:surgery*; D006323:Heart Arrest / Q000139:chemically induced* / Q000628:therapy; D006801:Humans; D007223:Infant; D008297:Male; D009388:Neostigmine / Q000009:adverse effects*; D010277:Parasympathomimetics / Q000009:adverse effects*
chemical_list: D010277:Parasympathomimetics; D009388:Neostigmine