title: Endobronchial tumours in a campaign for early detection of bronchial cancer: Computed tomography versus endoscopy.
abstract: OBJECTIVE
  To study endobronchial cancers occurring in a population at high risk of bronchial cancer (history of surgically treated bronchial or ENT cancer in complete remission, and symptoms due to smoking) detected by annual volume CT scans and biannual fibroscopy.
  
  
  METHODS
  Two hundred and sixty-six patients were included in this single centre prospective study; 27 bronchopulmonary cancers were detected. Ten endobronchial cancers (37%) were identified by fibroscopy (nine invasive cancers and one carcinoma in situ) in 10 patients (nine men) (51-78 years old) nine of whom were smokers (dark tobacco: seven). The screening CTs were reappraised by two radiologists.
  
  
  RESULTS
  Three cancers out of 10 were detected by CT during the initial reading. The sensitivity of the reappraised CT was 80% with seven false positives. In five cases, the mean period between the first CT scan where the lesion was visible retrospectively, but not described, and the diagnostic fibroscopy was 463 days (213-808 days); two cancers were not visible in the CT scan. Seven curative treatments were undertaken.
  
  
  CONCLUSIONS
  In this population, the sensitivity of the initial reading of the CT scan for detecting endobronchial tumours was 30%, while 80% of the tumours were visible retrospectively, underlining the importance of careful analysis of the proximal bronchial tree.
authors: Clinique universitaire de radiologie et d'imagerie médicale, CHU de Grenoble, BP 217, Grenoble cedex 09, France.
authors: B
authors: B
authors: Lecourtois
authors: A
authors: A
authors: Jankowski
authors: F
authors: F
authors: Arbib
authors: S
authors: S
authors: Lantuejoul
authors: P Y
authors: PY
authors: Brichon
authors: D
authors: D
authors: Moro-Sibilot
authors: C
authors: C
authors: Brambilla
authors: G
authors: G
authors: Ferretti
mesh_terms: D000368:Aged; D001984:Bronchial Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D001999:Bronchoscopy; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D005336:Fiber Optic Technology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed