title: Clinical and histopathological features of orbital granular cell tumor: case report.
abstract: A 53 year-old woman presented with a slowly progressive, painless proptosis OS. Computed tomography disclosed a round, homogeneous, well-delimited lesion in the inferior-temporal orbit. The tumor was composed of round cells with eosinophilic granular cytoplasm. Some of the cells had larger eosinophilic granules surrounded by a clear halo; known as pustulo-ovoid bodies of Milian or Bangle bodies. The diagnosis of a granular cell tumor was then established and confirmed by immunohistochemistry. Granular cell tumors are uncommon benign soft tissue neoplasms that have a predilection for the head and neck region. Awareness of the typical histopathological features is crucial for the correct diagnosis.
authors: Department of Ophthalmology and Pathology, Henry C. Witelson Ocular Pathology Laboratory & McGill University Health Centre, Montreal, QC, Canada.
authors: Bruno F
authors: BF
authors: Fernandes
authors: Rubens
authors: R
authors: Belfort Neto
authors: Alexandre Nakao
authors: AN
authors: Odashiro
authors: Patricia Rusa
authors: PR
authors: Pereira
authors: Miguel N
authors: MN
authors: Burnier
mesh_terms: D005260:Female; D016586:Granular Cell Tumor / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D014057:Tomography, X-Ray Computed