title: Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds.
abstract: Alginate microribbons with longitudinally grooved microstructures are continuously fabricated by means of a microfluidic system. The number and dimensions of the microgroovesare successfully controlled by regulation of the slit-shaped channel (yellow in figure). This method opens up the possibility of mass production of scaffolds for tissue engineering purposes, as it is proved that the grooved flat fibers can be used to align other types of cells in culture.
authors: Department of Biomedical Engineering, College of Health Science, Korea University, Seoul, 136-703, Republic of Korea.
authors: Edward
authors: E
authors: Kang
authors: Yoon Young
authors: YY
authors: Choi
authors: Su-Kyoung
authors: SK
authors: Chae
authors: Jin-Hee
authors: JH
authors: Moon
authors: Joon-Young
authors: JY
authors: Chang
authors: Sang-Hoon
authors: SH
authors: Lee
mesh_terms: D000464:Alginates / Q000737:chemistry*; D000818:Animals; D002478:Cells, Cultured; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D020723:Glucuronic Acid / Q000737:chemistry; D006603:Hexuronic Acids / Q000737:chemistry; D046210:Microfluidic Analytical Techniques; D008856:Microscopy, Fluorescence; D009474:Neurons / Q000166:cytology; D051381:Rats; D017207:Rats, Sprague-Dawley; D023822:Tissue Engineering
chemical_list: D000464:Alginates; D004129:Dimethylpolysiloxanes; D006603:Hexuronic Acids; C013830:baysilon; D020723:Glucuronic Acid