title: The effect of monochromatic infrared energy on diabetic wound healing.
abstract: This study examined the effect of monochromatic infrared energy (MIRE) on diabetic wound healing. Fifteen diabetic rats were given MIRE intervention on their skin wounds located on the dorsum and compared with 15 control diabetic rats. Assessments were conducted for each group at weeks 1, 2 and 4 post wounding (five rats at each time point) by calculating the percentage of wound closures (WCs) and performing histological and immunohistochemical staining on sections of wound tissue. Evaluations of WCs and histological examinations of reepithelialisation, cellular content and granulation tissue formation showed no significant difference between the MIRE and the control group at each time point. Through semi-quantitative immunohistochemical staining, the deposition of type I collagen in the MIRE group was found to have improved when compared with the control group at the end of week 2 (P = 0.05). No significant differences in the myofibroblast population were detected between the two groups. In conclusion, MIRE appeared to promote collagen deposition in the early stage of wound healing in diabetic rats, but the overall wound healing in the MIRE group was not significantly different from that of the control group.
authors: Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong (SAR), China.
authors: Yayi
authors: Y
authors: He
authors: Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong (SAR), ChinaDepartment of Endocrinology, First Affiliated Hospital of Xi'an Jiaotong University College of Medicine, Xi'an, ChinaDivision of Plastic, Reconstructive and Aesthetic Surgery, Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong (SAR), ChinaDepartment of Physiology and Pathophysiology, Medical School of Xi'an Jiaotong University, Xi'an, China.
authors: Selina Ly
authors: SL
authors: Yip
authors: Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong (SAR), ChinaDepartment of Endocrinology, First Affiliated Hospital of Xi'an Jiaotong University College of Medicine, Xi'an, ChinaDivision of Plastic, Reconstructive and Aesthetic Surgery, Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong (SAR), ChinaDepartment of Physiology and Pathophysiology, Medical School of Xi'an Jiaotong University, Xi'an, China.
authors: Kwok-Kuen
authors: KK
authors: Cheung
authors: Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong (SAR), ChinaDepartment of Endocrinology, First Affiliated Hospital of Xi'an Jiaotong University College of Medicine, Xi'an, ChinaDivision of Plastic, Reconstructive and Aesthetic Surgery, Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong (SAR), ChinaDepartment of Physiology and Pathophysiology, Medical School of Xi'an Jiaotong University, Xi'an, China.
authors: Lin
authors: L
authors: Huang
authors: Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong (SAR), ChinaDepartment of Endocrinology, First Affiliated Hospital of Xi'an Jiaotong University College of Medicine, Xi'an, ChinaDivision of Plastic, Reconstructive and Aesthetic Surgery, Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong (SAR), ChinaDepartment of Physiology and Pathophysiology, Medical School of Xi'an Jiaotong University, Xi'an, China.
authors: Shijie
authors: S
authors: Wang
authors: Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong (SAR), ChinaDepartment of Endocrinology, First Affiliated Hospital of Xi'an Jiaotong University College of Medicine, Xi'an, ChinaDivision of Plastic, Reconstructive and Aesthetic Surgery, Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong (SAR), ChinaDepartment of Physiology and Pathophysiology, Medical School of Xi'an Jiaotong University, Xi'an, China.
authors: Gladys Ly
authors: GL
authors: Cheing
mesh_terms: D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000150:complications*; D007259:Infrared Rays / Q000627:therapeutic use*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012867:Skin / Q000293:injuries* / Q000473:pathology; D014945:Wound Healing / Q000528:radiation effects*; D014947:Wounds and Injuries / Q000150:complications / Q000473:pathology / Q000532:radiotherapy*