title: [Tolerance of adjuvant radiotherapy in the treatment of stage I seminoma].
abstract: OBJECTIVE
  To assess the tolerance of adjuvant radiotherapy in the treatment of stage I seminoma post-orchiectomy.
  
  
  METHODS
  Between 2001 and 2006, 21 men with stage I seminoma underwent 3D conformal radiotherapy 3 to 4 weeks post-orchiectomy. The total radiation dose was 2490 cGy divided into 15 sessions. Radiation was delivered by 2 antero-posterior fields using X-ray photons of 18 MV. Two types of radiation fields were used : para-aortic and ipsilateral iliac (dog leg) or para-aortic only. The average followup was 2 years 4 months with an interval of 4 to 58 months. Tolerance of treatment was evaluated according to criteria of the RTOG.
  
  
  RESULTS
  Median follow-up time is 30 months. Disease-free survival was 100%. The most frequently encountered acute toxicity was gastrointestinal; mainly nausea and vomiting. Tolerance to treatment was better in the group receiving para-aortic radiotherapy alone (37% of grade II gastrointestinal toxicity vs 62%)
  
  
  CONCLUSIONS
  The para-aortic irradiation for stage I seminoma gave satisfactory results with a better toxicity profile than the dogleg irradiation.
authors: Service de Radiothérapie, CHU Hôtel-Dieu de France, Beyrouth, Liban. nasre@inco.com.lb
authors: Elie
authors: E
authors: Nasr
authors: Joelle
authors: J
authors: Helou
authors: Dolly
authors: D
authors: Nehmé Nasr
authors: Jose Gregorio
authors: JG
authors: Younes
authors: Elie
authors: E
authors: Nemr
authors: Maroun
authors: M
authors: Moukarzel
authors: Fares
authors: F
authors: Azoury
authors: Sleiman
authors: S
authors: Merhej
mesh_terms: D000328:Adult; D018572:Disease-Free Survival; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009919:Orchiectomy; D018714:Radiotherapy, Adjuvant; D018239:Seminoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D013736:Testicular Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D055815:Young Adult