title: Identification of a novel resistance mutation in parE that confers high-level resistance to moxifloxacin in Streptococcus pneumoniae.
authors: Gang
authors: G
authors: Zhang
authors: Wenyu
authors: W
authors: Tian
authors: Chao
authors: C
authors: Wang
authors: Jie
authors: J
authors: Feng
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001372:Aza Compounds / Q000494:pharmacology*; D027101:DNA Topoisomerase IV / Q000235:genetics*; D024881:Drug Resistance, Bacterial; D024841:Fluoroquinolones; D006801:Humans; D008826:Microbial Sensitivity Tests; D000077266:Moxifloxacin; D020125:Mutation, Missense; D011804:Quinolines / Q000494:pharmacology*; D012692:Serial Passage; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000201:enzymology* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D001372:Aza Compounds; D024841:Fluoroquinolones; D011804:Quinolines; D027101:DNA Topoisomerase IV; D000077266:Moxifloxacin