title: Novel antimicrobial organic thermal stabilizer and co-stabilizer for rigid PVC.
abstract: Biologically active N-benzoyl-4-(N-maleimido)-phenylhydrazide (BMPH) was synthesized and its structure was confirmed by elemental analysis and various spectral tools. It was examined as a thermal stabilizer and co-stabilizer for rigid poly (vinyl chloride) at 180 °C in air. Blending BMPH with reference samples in different ratios greatly lengthens the thermal stability value and improves the extent of discoloration of PVC. TGA confirmed the improved stability of PVC in presence of the investigated organic stabilizer. GPC measurements were done to investigate the changes occurred in the molecular masses of the degraded samples of blank PVC and PVC in presence of the novel stabilizer. BMPH showed good antimicrobial activity towards two kinds of bacteria and two kinds of fungi.
authors: Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt.
authors: Mona M
authors: MM
authors: Fahmy
authors: Riham R
authors: RR
authors: Mohamed
authors: Nadia A
authors: NA
authors: Mohamed
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002850:Chromatography, Gel; D003116:Color; D005079:Excipients / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects; D054879:Halogenation / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008970:Molecular Weight; D010659:Phenylhydrazines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D011143:Polyvinyl Chloride / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013696:Temperature; D013818:Thermogravimetry
chemical_list: D000890:Anti-Infective Agents; D005079:Excipients; D010659:Phenylhydrazines; C030299:phenylhydrazine; D011143:Polyvinyl Chloride