title: Recent research on bovine paratuberculosis in South Korea.
abstract: Bovine paratuberculosis (Johne's disease), a chronic and debilitating disease of ruminants caused by Mycobacterium avium subspecies paratuberculosis (MAP), is a major cause of chronic ruminant enteritis. A national eradication program has been in place in South Korea since the first report of the disease in 1967; however, only limited data on bovine paratuberculosis in South Korea are available. Some research, such as investigations of the reactivity of animal sera against MAP antigens, has been done in localized areas and in limited animal species. Compared with the worldwide situation, the development of diagnostic methods in South Korea has shown similar results even though some data were obtained from international collaborative studies. MAP is considered by some to be zoonotic, noting an association with Crohn's disease, although this issue is still controversial; however, research into this association is limited. Decisions based on disease priorities have hampered active progress in research on the disease. In this paper, we reviewed the available results generated from South Korea compared with global research. Finally, we propose a theme for future research.
authors: Department of Infectious Diseases, College of Veterinary Medicine, Research Institute for Veterinary Science and BK21 for Veterinary Science, Seoul National University, Seoul 151-742, South Korea. yoohs@snu.ac.kr
authors: Han Sang
authors: HS
authors: Yoo
authors: Sung Jae
authors: SJ
authors: Shin
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control; D060740:Disease Eradication; D016927:Mycobacterium avium subsp. paratuberculosis / Q000276:immunology / Q000302:isolation & purification; D010283:Paratuberculosis / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control; D056910:Republic of Korea / Q000453:epidemiology