title: High-throughput and sensitive analysis of 3-monochloropropane-1,2-diol fatty acid esters in edible oils by supercritical fluid chromatography/tandem mass spectrometry.
abstract: We have established a high-throughput and sensitive analytical method based on supercritical fluid chromatography (SFC) coupled with triple quadrupole mass spectrometry (QqQ MS) for 3-monochloropropane-1,2-diol (3-MCPD) fatty acid esters in edible oils. All analytes were successfully separated within 9 min without sample purification. The system was precise and sensitive, with a limit of detection less than 0.063 mg/kg. The recovery rate of 3-MCPD fatty acid esters spiked into oil samples was in the range of 62.68-115.23%. Furthermore, several edible oils were tested for analyzing 3-MCPD fatty acid ester profiles. This is the first report on the analysis of 3-MCPD fatty acid esters by SFC/QqQ MS. The developed method will be a powerful tool for investigating 3-MCPD fatty acid esters in edible oils.
authors: Analytical Center for Food Safety, Quality Assurance Department, Fuji Oil Co. Ltd., 1 Sumiyoshi-Cho, Izumisano, Osaka 598-8540, Japan.
authors: Katsuhito
authors: K
authors: Hori
authors: Atsuki
authors: A
authors: Matsubara
authors: Takato
authors: T
authors: Uchikata
authors: Kazunobu
authors: K
authors: Tsumura
authors: Eiichiro
authors: E
authors: Fukusaki
authors: Takeshi
authors: T
authors: Bamba
mesh_terms: D025924:Chromatography, Supercritical Fluid / Q000379:methods*; D005227:Fatty Acids / Q000032:analysis* / Q000737:chemistry; D005990:Glycerol / Q000031:analogs & derivatives* / Q000737:chemistry; D057166:High-Throughput Screening Assays / Q000379:methods*; D057230:Limit of Detection; D010938:Plant Oils / Q000737:chemistry*; D015203:Reproducibility of Results; D053719:Tandem Mass Spectrometry / Q000379:methods*; D000517:alpha-Chlorohydrin
chemical_list: D005227:Fatty Acids; D010938:Plant Oils; D000517:alpha-Chlorohydrin; D005990:Glycerol