title: Effect of auditory isolation on activity-based anorexia.
abstract: The objective was to study male and female rats exposed to Activity-Based Anorexia (ABA; simultaneous exposition to food restriction and free access to an activity wheel) under two conditions of sound attenuation, by means of different arrangements of wheels (standard versus isolation) in the laboratory room. Regardless of the sound attenuation condition, all but one male and one female with access to wheels had to be removed from the experiment, but extended ABA endurance was found in rats in the sound attenuation condition. Furthermore, significantly lower levels of running were observed in both males and females under the sound attenuation arrangement in the isolation condition. The results suggest that external stimulation plays a role in the activity displayed by rats exposed to ABA, and that the reduction of external stimulation diminishes running but does not protect rats from developing ABA.
authors: Universidad de Santiago de Compostela.
authors: Ángela
authors: Á
authors: Fraga
authors: Belén
authors: B
authors: De Pedro
authors: María
authors: M
authors: Cerrato
authors: Olaia
authors: O
authors: Carrera
authors: Emilio
authors: E
authors: Gutiérrez
mesh_terms: D000161:Acoustic Stimulation; D000818:Animals; D000855:Anorexia / Q000209:etiology*; D001835:Body Weight; D004435:Eating; D005247:Feeding Behavior / Q000523:psychology*; D005260:Female; D005508:Food Deprivation / Q000502:physiology*; D006799:Housing, Animal; D008297:Male; D009043:Motor Activity / Q000502:physiology*; D009622:Noise; D010807:Physical Endurance; D011897:Random Allocation; D051381:Rats; D017207:Rats, Sprague-Dawley; D012420:Running / Q000502:physiology; D057185:Sedentary Behavior; D015431:Weight Loss