title: Biomimetic models for the active site of [Fe]hydrogenase featuring an acylmethyl(hydroxymethyl)pyridine ligand.
abstract: The first acylmethyl(hydroxymethyl)pyridine ligand-containing [Fe]hydrogenase model complexes 2-4 have been synthesized starting from the nucleophilic substitution reaction of 2-(4-MeC(6)H(4)SO(3)CH(2))-6-HOCH(2)C(5)H(3)N with Na(2)Fe(CO)(4). While the reaction course for producing complex 3 via the highly unstable intermediate complex 1 is monitored by in situ IR spectroscopy, the isolated model complexes 2-4 are fully characterized.
authors: State Key Laboratory of Elemento-Organic Chemistry, Department of Chemistry, Nankai University, Tianjin 300071, China. lcsong@nankai.edu.cn
authors: Li-Cheng
authors: LC
authors: Song
authors: Zhao-Jun
authors: ZJ
authors: Xie
authors: Miao-Miao
authors: MM
authors: Wang
authors: Gao-Yu
authors: GY
authors: Zhao
authors: Hai-Bin
authors: HB
authors: Song
mesh_terms: D040761:Biomimetic Materials / Q000138:chemical synthesis* / Q000737:chemistry; D032701:Biomimetics; D020134:Catalytic Domain; D018360:Crystallography, X-Ray; D006864:Hydrogenase / Q000737:chemistry* / Q000378:metabolism; D007506:Iron-Sulfur Proteins / Q000737:chemistry* / Q000378:metabolism; D008024:Ligands; D008958:Models, Molecular; D015394:Molecular Structure; D011725:Pyridines / Q000737:chemistry*
chemical_list: D007506:Iron-Sulfur Proteins; D008024:Ligands; D011725:Pyridines; C576292:acylmethyl(hydroxymethyl)pyridine; C118830:iron hydrogenase; D006864:Hydrogenase