title: [Morphometric and functional features of macula in patients with high congenital myopia].
abstract: Combined use of OCT and ERG allowed us to study correlation of functional changes and morphological retinal features in patients with congenital myopia with or without myopic maculopathy. The study revealed the following features of retinal contour in macula region in congenital myopia compared to emmetropia: increase of neuroepithelial thickness in fovea centre, trend to decrease of its thickness in perifoveolar zone, significant (1,7-fold) reduction of neuroepithelial thickness difference between central and pericentral zones and subsequently change of retinal profile. Revealed data should be considered in retinal thickness evaluation of adults with high myopia and in assessment of normal postnatal macula development in children with high myopia. Combination of ophthalmoscopy, OCT and m-ERG may help in early diagnosis and monitoring of progressing macula changes.
authors: E P
authors: EP
authors: Tarutta
authors: G A
authors: GA
authors: Markosian
authors: M V
authors: MV
authors: Riabina
authors: I V
authors: IV
authors: Zol'nikova
authors: G V
authors: GV
authors: Kruzhkova
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D018450:Disease Progression; D042241:Early Diagnosis; D004596:Electroretinography / Q000379:methods; D058453:Emmetropia; D005260:Female; D005584:Fovea Centralis / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D009216:Myopia / Q000151:congenital / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology; D009887:Ophthalmoscopy / Q000379:methods; D012164:Retinal Diseases / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology; D041623:Tomography, Optical Coherence / Q000379:methods