title: Regenerative surgery: tissue engineering in general surgical practice.
abstract: Tissue engineering is a broad interdisciplinary field that aims to develop complex tissue and organ constructs through a combination of cell-, biomaterial-, and molecular-based approaches. This approach has the potential to transform the surgical treatment for diseases including trauma, cancer, and congenital malformations. A fundamental knowledge of key concepts in regenerative medicine is imperative for surgeons to maintain a leading role in developing and implementing these technologies. Researchers have started to elucidate the biologic mechanisms that maintain organ homeostasis throughout life, indicating that humans may have the latent capacity to regenerate complex tissues. By exploiting this intrinsic potential of the body, we can move even closer to developing functional, autologous replacement parts for a wide range of surgical diseases.
authors: Department of Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA. vicw.wong@gmail.com
authors: Victor W
authors: VW
authors: Wong
authors: Derrick C
authors: DC
authors: Wan
authors: Geoffrey C
authors: GC
authors: Gurtner
authors: Michael T
authors: MT
authors: Longaker
mesh_terms: D005544:Forecasting; D013502:General Surgery / Q000379:methods* / Q000639:trends; D006801:Humans; D044968:Regenerative Medicine / Q000379:methods* / Q000639:trends; D013514:Surgical Procedures, Operative / Q000379:methods* / Q000639:trends; D023822:Tissue Engineering