title: Stabilising fluorescent silica nanoparticles against dissolution effects for biological studies.
abstract: Here we show that commonly employed Stöber type fluorescently labelled silica nanoprobes degrade by hydrolytic dissolution, accelerated under biological media conditions as compared to water alone. We have thus developed a method to greatly improve their stability under such conditions.
authors: Centre for BioNano Interactions, School of Chemistry and Chemical Biology, UCD Conway Institute for Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland. eugene.mahon@cbni.ucd.ie
authors: Eugene
authors: E
authors: Mahon
authors: Delyan R
authors: DR
authors: Hristov
authors: Kenneth A
authors: KA
authors: Dawson
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D005453:Fluorescence; D006868:Hydrolysis; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D012822:Silicon Dioxide / Q000737:chemistry*; D012995:Solubility; D013499:Surface Properties
chemical_list: D000596:Amino Acids; D012822:Silicon Dioxide