title: Tooth loss and risk of hip  fracture: a prospective study of  male Japanese dentists.
abstract: OBJECTIVE
  To determine whether the number of teeth lost can predict the risk of subsequent hip fracture.
  
  
  METHODS
  We followed up 9992 male Japanese dentists aged 50 years or more (mean age ± standard deviation [SD], 61.1 ± 9.6 years) for incidence of hip fracture. From 2001 through 2006, they completed a baseline questionnaire on lifestyle and health factors including the number of teeth lost (excluding third molars). Incidence rate ratios (IRRs) were estimated by fitting proportional hazard models.
  
  
  RESULTS
  During the mean follow-up period of 6.0 years, 20 new cases of hip fracture occurred. Participants who had lost 15 or more teeth at baseline were at a significantly increased risk of hip fracture: the multivariate-adjusted IRRs were 4.1 (95% confidence interval [CI], 1.2-14.2) for loss of 15-27 teeth and 4.5 (1.1-18.0) for edentulousness relative to loss of 0-14 teeth (trend P, 0.028). Overall, the risk of hip fracture was weakly associated with the number of teeth lost: the IRR per tooth was 1.06 (95% CI, 1.01-1.12).
  
  
  CONCLUSIONS
  Tooth loss was slightly associated with a higher risk of subsequent hip fracture. The number of teeth lost might be informative in predicting this risk.
authors: Kenji
authors: K
authors: Wakai
authors: Mariko
authors: M
authors: Naito
authors: Toru
authors: T
authors: Naito
authors: Masaaki
authors: M
authors: Kojima
authors: Haruo
authors: H
authors: Nakagaki
authors: Osami
authors: O
authors: Umemura
authors: Makoto
authors: M
authors: Yokota
authors: Nobuhiro
authors: N
authors: Hanada
authors: Takashi
authors: T
authors: Kawamura
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003815:Dentists / Q000706:statistics & numerical data; D006620:Hip Fractures / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D016388:Tooth Loss / Q000150:complications*