title: Morphology regulatory metabolites from Arthrobotrys oligospora.
abstract: Novel autoregulatory metabolites, arthrosporols A-C (1-3), involved in regulating the morphological switch in fungi, were purified and characterized from the carnivorous fungus Arthrobotrys oligospora. These compounds possess a novel hybrid carbon skeleton consisting of an epoxy-cyclohexenol combined with a rare monocyclic sesquiterpenol substructure. This is the first report of a monocyclic sesquiterpenol of this type of fungal origin. Compounds 1-3 displayed significant inhibitory activities toward the formation of conidiophores, while compounds 1 and 3 showed the opposite effects on the formation of a two-dimensional network with increasing rates of 40-90% and inhibiting rates of 30-90%, respectively.
authors: Laboratory for Conservation and Utilization of Bio-Resources & Key Laboratory for Microbial Resources of the Ministry of Education,  Yunnan University , Kunming, 650091, People's Republic of China.
authors: Hui-Xiang
authors: HX
authors: Zhang
authors: Jian-Lin
authors: JL
authors: Tan
authors: Lu-Xia
authors: LX
authors: Wei
authors: Yan-Li
authors: YL
authors: Wang
authors: Chuan-Ping
authors: CP
authors: Zhang
authors: De-Kai
authors: DK
authors: Wu
authors: Chun-Yan
authors: CY
authors: Zhu
authors: Ying
authors: Y
authors: Zhang
authors: Ke-Qin
authors: KQ
authors: Zhang
authors: Xue-Mei
authors: XM
authors: Niu
mesh_terms: D001203:Ascomycota / Q000737:chemistry*; D002681:China; D003511:Cyclohexanols / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D003511:Cyclohexanols; D012717:Sesquiterpenes