title: [Tympanotomy and sealing of the round window membrane in sudden sensorineural hearing loss: a retrospective analysis].
abstract: BACKGROUND
  The pathogenesis of idiopathic sudden sensorineural hearing loss (ISSHL) still remains unclear. This retrospective study was performed to evaluate the effectiveness of tympanotomy and sealing of the round window membrane after unilateral idiopathic sudden sensorineural hearing loss.
  
  
  METHODS
  A total of 74 patients with idiopathic sudden sensorineural hearing loss were treated with antiphlogistic-rheologic infusion therapy according to Stennert (steroids and pentoxyphylline). In addition, all patients underwent exploratory tympanotomy and sealing of the round window membrane. Pure tone audiometry was performed pre- and postinterventionally.
  
  
  RESULTS
  The average hearing loss (four pure tone average) of all patients was 58.9 dB pre-, and 46 dB postinterventionally, which is an average improvement of 12.9 dB. Patients with hearing loss of more than 60% improved significantly compared to patients with hearing loss less than 60% (33.9% vs. +3.3%). Sealing of the round window membrane was found to be more effective when performed within 8 days after ISSHL. A membrane rupture did not lead to better therapy results. No significant correlation was found between therapy outcome and other clinical symptoms.
  
  
  CONCLUSIONS
  Sealing of the window membrane shows equal results to conservative methods. If patients with hearing loss of more than 60% have more benefit in tympanotomy with sealing of the window membrane than patients with less hearing loss--as shown as in this study--has to be proved in randomized examinations. Intraoperatively found ruptures of the round window membrane had no significant effect on the therapy outcome.
authors: Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halsschirurgie, Klinikum Bielefeld, Teutoburger Str. 50, 33604, Bielefeld, Deutschland. ulfreineke@web.de
authors: U
authors: U
authors: Reineke
authors: M
authors: M
authors: Hühnerschulte
authors: J
authors: J
authors: Ebmeyer
authors: H
authors: H
authors: Sudhoff
mesh_terms: D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D009225:Myringoplasty / Q000379:methods*; D012189:Retrospective Studies; D012405:Round Window, Ear / Q000601:surgery*; D016896:Treatment Outcome; D014433:Tympanoplasty / Q000379:methods*