title: Acute cerebellar infarction associated with intravenous gammaglobulin treatment in idiopathic thrombocytopenic purpura.
abstract: Intravenous immunoglobulins (IVIGs) are used for a variety of immunologic and hematologic disorders. Hemorheologic alteration or the rapid increase of platelet counts by IVIG administration can cause thrombotic adverse events. We present a 58-year-old woman with a previous diagnosis of idiopathic thrombocytopenic purpura who developed cerebellar infarction immediately after IVIG treatment. We discuss a possible role of IVIG in cerebral ischemia and management strategies.
authors: Department of Neurology, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Kangwon-do, Korea.
authors: Woo-Joo
authors: WJ
authors: Choi
authors: Min-Jee
authors: MJ
authors: Kim
authors: Chulho
authors: C
authors: Kim
authors: Jong Hee
authors: JH
authors: Sohn
authors: Hui-Chul
authors: HC
authors: Choi
mesh_terms: D001241:Aspirin / Q000627:therapeutic use; D020520:Brain Infarction / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D002531:Cerebellum / Q000098:blood supply* / Q000187:drug effects* / Q000473:pathology; D002533:Cerebral Angiography / Q000379:methods; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage / Q000009:adverse effects*; D007262:Infusions, Intravenous; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000175:diagnosis / Q000188:drug therapy*; D013997:Time Factors; D016896:Treatment Outcome; D005719:gamma-Globulins / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D016756:Immunoglobulins, Intravenous; D005719:gamma-Globulins; D001241:Aspirin