title: A multidisciplinary approach to the treatment of anti-NMDA-receptor antibody encephalitis: a case and review of the literature.
abstract: Anti-NMDAR (N-methyl-d-aspartate receptor) encephalitis is a novel autoimmune and paraneoplastic disease often presenting as acute psychosis. Few studies exist in the psychiatric literature on neuroimmunity and behavioral management. This article reviews the epidemiology, diagnosis, pathophysiology, and management of this disease from a neuropsychiatric perspective. Patients have potential for near-complete recovery with early diagnosis and intervention. In addition to immune-suppression and tumor removal, electroconvulsive therapy may be an important tool in treatment of the underlying process in cases developing life-threatening catatonia. Psychiatrists should be familiar with treatment options, since they may be consulted within the context of a multispecialty team.
authors: Department of Psychiatry and Behavioral Neuroscience, University of Chicago Medical Center, Chicago, IL, USA. andrea.mann@uchospitals.edu
authors: Andrea
authors: A
authors: Mann
authors: Nikolas Mata
authors: NM
authors: Machado
authors: Ni
authors: N
authors: Liu
authors: Abdul-Hussein
authors: AH
authors: Mazin
authors: Kenneth
authors: K
authors: Silver
authors: Khalid I
authors: KI
authors: Afzal
mesh_terms: D000293:Adolescent; D060426:Anti-N-Methyl-D-Aspartate Receptor Encephalitis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology / Q000601:surgery / Q000628:therapy; D019468:Disease Management; D004565:Electroconvulsive Therapy / Q000523:psychology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000523:psychology; D010051:Ovarian Neoplasms / Q000601:surgery*; D010348:Patient Care Team / Q000458:organization & administration*; D011619:Psychotropic Drugs / Q000627:therapeutic use; D013724:Teratoma / Q000601:surgery*
chemical_list: D011619:Psychotropic Drugs