title: Automatic generation of anatomic characteristics from cerebral aneurysm surface models.
abstract: OBJECTIVE
  Computer-aided research on cerebral aneurysms often depends on a polygonal mesh representation of the vessel lumen. To support a differentiated, anatomy-aware analysis, it is necessary to derive anatomic descriptors from the surface model. We present an approach on automatic decomposition of the adjacent vessels into near- and far-vessel regions and computation of the axial plane. We also exemplarily present two applications of the geometric descriptors: automatic computation of a unique vessel order and automatic viewpoint selection.
  
  
  METHODS
  Approximation methods are employed to analyze vessel cross-sections and the vessel area profile along the centerline. The resulting transition zones between near- and far- vessel regions are used as input for an optimization process to compute the axial plane. The unique vessel order is defined via projection into the plane space of the axial plane. The viewing direction for the automatic viewpoint selection is derived from the normal vector of the axial plane.
  
  
  RESULTS
  The approach was successfully applied to representative data sets exhibiting a broad variability with respect to the configuration of their adjacent vessels. A robustness analysis showed that the automatic decomposition is stable against noise. A survey with 4 medical experts showed a broad agreement with the automatically defined transition zones.
  
  
  CONCLUSIONS
  Due to the general nature of the underlying algorithms, this approach is applicable to most of the likely aneurysm configurations in the cerebral vasculature. Additional geometric information obtained during automatic decomposition can support correction in case the automatic approach fails. The resulting descriptors can be used for various applications in the field of visualization, exploration and analysis of cerebral aneurysms.
authors: Department of Simulation and Graphics, University of Magdeburg, Universitätsplatz 2, 39106, Magdeburg, Germany. mathias.neugebauer@isg.cs.uni-magdeburg.de
authors: M
authors: M
authors: Neugebauer
authors: K
authors: K
authors: Lawonn
authors: O
authors: O
authors: Beuing
authors: B
authors: B
authors: Preim
mesh_terms: D000465:Algorithms; D002533:Cerebral Angiography / Q000379:methods*; D002560:Cerebrovascular Circulation; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional; D002532:Intracranial Aneurysm / Q000175:diagnosis*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*