title: In vitro phytotoxicity and antioxidant activity of selected flavonoids.
abstract: The knowledge of flavonoids involved in plant-plant interactions and their mechanisms of action are poor and, moreover, the structural characteristics required for these biological activities are scarcely known. The objective of this work was to study the possible in vitro phytotoxic effects of 27 flavonoids on the germination and early radical growth of Raphanus sativus L. and Lepidium sativum L., with the aim to evaluate the possible structure/activity relationship. Moreover, the antioxidant activity of the same compounds was also evaluated. Generally, in response to various tested flavonoids, germination was only slightly affected, whereas significant differences were observed in the activity of the various tested flavonoids against radical elongation. DPPH test confirms the antioxidant activity of luteolin, quercetin, catechol, morin, and catechin. The biological activity recorded is discussed in relation to the structure of compounds and their capability to interact with cell structures and physiology. No correlation was found between phytotoxic and antioxidant activities.
authors: Dipartimento di Scienze Farmaceutiche e Biomediche, Università degli Studi di Salerno, Via Ponte don Melillo, 84084 Fisciano, Salerno, Italy.
authors: Laura
authors: L
authors: De Martino
authors: Dipartimento di Scienze Farmaceutiche e Biomediche, Università degli Studi di Salerno, Via Ponte don Melillo, 84084 Fisciano, Salerno, Italy.
authors: Teresa
authors: 0000-0001-8207-0085
authors: T
authors: Mencherini
authors: Dipartimento di Scienze Farmaceutiche e Biomediche, Università degli Studi di Salerno, Via Ponte don Melillo, 84084 Fisciano, Salerno, Italy.
authors: Emilia
authors: E
authors: Mancini
authors: Dipartimento di Scienze Farmaceutiche e Biomediche, Università degli Studi di Salerno, Via Ponte don Melillo, 84084 Fisciano, Salerno, Italy.
authors: Rita Patrizia
authors: RP
authors: Aquino
authors: Departamento de Botânica, Instituto de Biociências de Botucatu, UNESP-Campu de Botucatu Distrito de Rubião Júnior, S/N, 18.618-000, Botucatu-SP, Brazil.
authors: Luiz Fernando Rolim
authors: LFR
authors: De Almeida
authors: Dipartimento di Scienze Farmaceutiche e Biomediche, Università degli Studi di Salerno, Via Ponte don Melillo, 84084 Fisciano, Salerno, Italy.
authors: Vincenzo
authors: 0000-0002-1070-3207
authors: V
authors: De Feo
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000494:pharmacology* / Q000633:toxicity; D001713:Biphenyl Compounds / Q000737:chemistry; D005419:Flavonoids / Q000737:chemistry* / Q000494:pharmacology* / Q000633:toxicity; D018525:Germination / Q000187:drug effects; D031220:Lepidium sativum / Q000187:drug effects / Q000254:growth & development*; D010851:Picrates / Q000737:chemistry; D031224:Raphanus / Q000187:drug effects / Q000254:growth & development*
chemical_list: D000975:Antioxidants; D001713:Biphenyl Compounds; D005419:Flavonoids; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl