title: Nanotechnology applications for glioblastoma.
abstract: Glioblastoma remains one of the most difficult cancers to treat and represents the most common primary malignancy of the brain. Although conventional treatments have found modest success in reducing the initial tumor burden, infiltrating cancer cells beyond the main mass are responsible for tumor recurrence and ultimate patient demise. Targeting residual infiltrating cancer cells requires the development of new treatment strategies. The emerging field of cancer nanotechnology holds promise in the use of multifunctional nanoparticles for imaging and targeted therapy of glioblastoma. This article examines the current state of nanotechnology in the treatment of glioblastoma and directions of further study.
authors: Department of Neurosurgery, Emory University School of Medicine, Winship Cancer Institute of Emory University, Atlanta, GA 30322, USA.
authors: Edjah K
authors: EK
authors: Nduom
authors: Alexandros
authors: A
authors: Bouras
authors: Milota
authors: M
authors: Kaluzova
authors: Costas G
authors: CG
authors: Hadjipanayis
mesh_terms: D001918:Brachytherapy / Q000295:instrumentation; D001932:Brain Neoplasms / Q000628:therapy*; D003287:Contrast Media / Q000627:therapeutic use; D016503:Drug Delivery Systems / Q000295:instrumentation; D018014:Gene Transfer Techniques / Q000295:instrumentation; D005909:Glioblastoma / Q000628:therapy*; D006801:Humans; D053758:Nanoparticles / Q000627:therapeutic use*; D036103:Nanotechnology / Q000639:trends; D010789:Phototherapy / Q000295:instrumentation
chemical_list: D003287:Contrast Media