title: Common criteria among States for storage and use of dried blood spot specimens after newborn screening.
abstract: Biological samples collected in biobanks are a resource with significant research potential. The Italian Joint Group CNB - CNBBSV (National Committee of Bioethics - National Committee for Biosecurity, Biotechnologies and Life Sciences) published a document reporting recommendations on storage and use of dried blood spot (DBS) and on the development of a National Network of Regional Newborn Screening Repositories for collection of residual DBS. Several ethical questions (about consent, possible use of genetic information, unanticipated possible usages for research purposes) rise from residual newborn screening specimens collections. Moreover, legal and ethical controversies are accentuated by the conflicts between the interests of sample donors, biobank holders, researchers and the public. To overcome these difficulties the identification of a few criteria for storage and research usage of DBS is crucial.
authors: Unità di Bioetica, Presidenza, Istituto Superiore di Sanità, Rome, Italy. carlo.petrini@iss.it
authors: Carlo
authors: C
authors: Petrini
authors: Antonella
authors: A
authors: Olivieri
authors: Carlo
authors: C
authors: Corbetta
authors: Roberto
authors: R
authors: Cerone
authors: Giuliano
authors: G
authors: D'Agnolo
authors: Adriano
authors: A
authors: Bompiani
mesh_terms: D000047:Academies and Institutes / Q000458:organization & administration; D018070:Biological Specimen Banks / Q000941:ethics / Q000458:organization & administration / Q000592:standards*; D001793:Blood Preservation / Q000941:ethics / Q000379:methods / Q000592:standards*; D001800:Blood Specimen Collection / Q000941:ethics / Q000379:methods / Q000592:standards*; D003890:Desiccation; D030661:Genetic Privacy / Q000592:standards*; D005820:Genetic Testing / Q000941:ethics / Q000379:methods; D006801:Humans; D007231:Infant, Newborn; D007558:Italy; D018580:Mandatory Testing / Q000941:ethics / Q000379:methods; D008910:Minnesota; D015997:Neonatal Screening / Q000941:ethics / Q000379:methods; D033282:Parental Consent; D011368:Professional-Family Relations; D013048:Specimen Handling / Q000592:standards