title: Swine flu: false-positive rapid flu swab with resulting misdiagnosis of a case of Legionella pneumonia.
abstract: A 59-year-old man presented with a severe flu-like illness and widespread pulmonary infiltrates on chest x-ray. A rapid influenza direct test was positive and the patient was nursed in isolation. On subsequent review, a diagnosis of probable atypical pneumonia was made, which was confirmed with positive urinary serology for Legionella pneumophila and treatment with appropriate antibiotics was started. A real-time PCR test for influenza A and B was negative at 72 h. The patient made a slow but full recovery and was discharged after 14 days.
authors: Department of Medicine, Countess of Chester NHS Trust, Chester, UK.
authors: Robert
authors: R
authors: Schofield
authors: Roger J
authors: RJ
authors: Trent
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000627:therapeutic use; D004279:DNA, Viral / Q000032:analysis; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D004636:Emergency Service, Hospital; D005189:False Positive Reactions; D005500:Follow-Up Studies; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000175:diagnosis* / Q000188:drug therapy; D016952:Legionella pneumophila / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic / Q000379:methods; D060888:Real-Time Polymerase Chain Reaction / Q000379:methods; D018570:Risk Assessment; D013552:Swine; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D004279:DNA, Viral