title: Exercise as a therapeutic tool to counteract inflammation and clinical symptoms in autoimmune rheumatic diseases.
abstract: Chronic inflammation is a common feature shared by several autoimmune rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, idiopathic inflammatory myopathies, systemic sclerosis, and ankylosing spondylitis. Therefore, blocking or reducing inflammation is one of the major treatment strategies in these diseases. In this context, exercise training has emerged as a potential therapeutic tool in counteracting systemic inflammation, thereby leading to better clinical outcomes. The aims of this review are i) to provide a summary of the clinical effects of exercise training in selected autoimmune rheumatic diseases; and ii) to discuss the potential anti-inflammatory role of exercise training in autoimmune rheumatic diseases, stressing the gaps in literature and the clinical and scientific perspectives in the field.
authors: Rheumatology Division, School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
authors: Luiz Augusto
authors: LA
authors: Perandini
authors: Ana Lúcia
authors: AL
authors: de Sá-Pinto
authors: Hamilton
authors: H
authors: Roschel
authors: Fabiana Braga
authors: FB
authors: Benatti
authors: Fernanda Rodrigues
authors: FR
authors: Lima
authors: Eloisa
authors: E
authors: Bonfá
authors: Bruno
authors: B
authors: Gualano
mesh_terms: D001327:Autoimmune Diseases / Q000628:therapy; D015444:Exercise; D005081:Exercise Therapy; D006801:Humans; D007249:Inflammation / Q000628:therapy*; D012216:Rheumatic Diseases / Q000628:therapy*