title: Novel 12-membered non-antibiotic macrolides, EM900 series with anti-inflammatory and/or immunomodulatory activity; synthesis, structure-activity relationships and in vivo study.
authors: Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan.
authors: Akihiro
authors: A
authors: Sugawara
authors: Akito
authors: A
authors: Sueki
authors: Tomoyasu
authors: T
authors: Hirose
authors: Hideaki
authors: H
authors: Shima
authors: Kiyoko S
authors: KS
authors: Akagawa
authors: Satoshi
authors: S
authors: Omura
authors: Toshiaki
authors: T
authors: Sunazuka
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D045744:Cell Line, Tumor; D003424:Crohn Disease / Q000188:drug therapy; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007155:Immunologic Factors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013329:Structure-Activity Relationship
chemical_list: D000893:Anti-Inflammatory Agents; D007155:Immunologic Factors; D018942:Macrolides