title: [Diagnostics and exclusion of hereditary angioedema : a standarized approach for the practice].
abstract: The differentiation between mast cell mediator-mediated and bradykinin-mediated forms of angioedema can be difficult. Bradykinin-mediated hereditary angioedema is a rare autosomal dominant hereditary disease which is characterized by recurrent edema attacks of varying magnitude. The edema occurs in the skin and mucous membranes and can be temporarily disfiguring, very painful and life-threatening by attacks in the laryngeal region. Because of the multitude of differential diagnoses, a final diagnosis is only achieved after an average duration of more than 10 years. The anamnestic and laboratory diagnostic algorithm presented here is designed to assist a simpler differentiation of the various forms of angioedema and to reach the correct diagnosis more quickly.
authors: Klinik für Dermatologie, Venerologie und Allergologie, Allergie-Centrum, Charité - Universitätsmedizin Berlin, Deutschland. markus.magerl@charite.de
authors: M
authors: M
authors: Magerl
authors: J
authors: J
authors: Brasch
authors: U
authors: U
authors: Förster
authors: B
authors: B
authors: Hauswald
authors: E B
authors: EB
authors: Mohr
authors: B
authors: B
authors: Mohr
authors: J
authors: J
authors: Prässler
authors: R
authors: R
authors: Treudler
authors: R
authors: R
authors: Vetter
authors: V
authors: V
authors: Wahn
authors: V
authors: V
authors: Zampeli
authors: V
authors: V
authors: Zampelli
authors: M
authors: M
authors: Ziemer
authors: M
authors: M
authors: Maurer
mesh_terms: D000465:Algorithms; D054179:Angioedemas, Hereditary / Q000145:classification* / Q000175:diagnosis*; D003880:Dermatology / Q000592:standards*; D003937:Diagnosis, Differential; D006801:Humans; D017410:Practice Guidelines as Topic