title: Lymphoma in inflammatory bowel disease and treatment decisions.
abstract: The risk of lymphoma, particularly non-Hodgkin's lymphoma, is an important concern associated with therapy for inflammatory bowel disease (IBD). Lymphoma risks have been described for nearly all immunomodulatory therapies for IBD, and it is therefore important to have discussions with patients before initiating therapy. However, it is also important to put risks into contexts that IBD patients can appropriately appreciate. Relative risks can appear large for these medications, while, by contrast, the absolute risk may be quite low. Additionally, understanding the risks of foregoing immunomodulatory therapy--specifically, continued active disease and/or continued corticosteroid use--can frame an appropriate risk-benefit discussion for both patients and physicians.
authors: Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. meenakshi.bewtra@uphs.upenn.edu
authors: Meenakshi
authors: M
authors: Bewtra
mesh_terms: D003657:Decision Making; D018450:Disease Progression; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy*; D008223:Lymphoma / Q000139:chemically induced*; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: D007166:Immunosuppressive Agents