title: Community-associated methicillin-resistant Staphylococcus aureus and athletes.
abstract: The remarkable ability of Staphylococcus aureus to develop antibiotic resistance in conjunction with the emergence of highly virulent and/or transmissible strains has established the pathogen as a leading cause of human bacterial infections worldwide. Historically, methicillin-resistant S aureus (MRSA) was found almost exclusively in hospitals and/or health care-related facilities. However, in the late 1990s, community-associated MRSA strains emerged in the United States and rapidly became the leading cause of community-associated bacterial infections. An enhanced understanding of the pathogenesis and epidemiology of this bacterium is fundamental for the prevention and/or treatment of community-associated MRSA infections. This review highlights salient features of S aureus biology that contribute to the exceptional ability of this pathogen to cause human disease, as well as discusses, in brief, the established approaches for treatment and prevention of infection.
authors: Laboratory of Human Bacterial Pathogenesis, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institute of Health, Hamilton, MT 59840, USA. fdeleo@niaid.nih.gov
authors: Natalia
authors: N
authors: Malachowa
authors: Scott D
authors: SD
authors: Kobayashi
authors: Frank R
authors: FR
authors: DeLeo
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D056352:Athletes; D001427:Bacterial Toxins / Q000378:metabolism; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000517:prevention & control; D004322:Drainage; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000378:metabolism / Q000472:pathogenicity*; D010353:Patient Education as Topic; D013178:Sports Medicine; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission
chemical_list: D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins