title: Generation of a library of non-toxic quantum dots for cellular imaging and siRNA delivery.
abstract: The development of non-toxic quantum dots and further investigation of their composition-dependent cytotoxicity in a high-throughput manner have been critical challenges for biomedical imaging and gene delivery. Herein, we report a rapid sonochemical synthetic methodology for generating a library of highly biocompatible ZnS-AgInS(2) (ZAIS) quantum dots for cellular imaging and siRNA delivery.
authors: Department of Chemistry and Chemical Biology, Institute for Advanced Materials, Devices and Nanotechnology, Rutgers, The State University of New Jersey, Piscataway, 08854, USA.
authors: Prasad
authors: P
authors: Subramaniam
authors: Seung Jae
authors: SJ
authors: Lee
authors: Shreyas
authors: S
authors: Shah
authors: Sahishnu
authors: S
authors: Patel
authors: Valentin
authors: V
authors: Starovoytov
authors: Ki-Bum
authors: KB
authors: Lee
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry / Q000378:metabolism; D045744:Cell Line, Tumor; D004337:Drug Carriers / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry; D018014:Gene Transfer Techniques; D006801:Humans; D008856:Microscopy, Fluorescence; D045663:Quantum Dots; D034741:RNA, Small Interfering / Q000378:metabolism*; D013234:Stem Cells / Q000187:drug effects / Q000378:metabolism; D013440:Sulfides / Q000737:chemistry; D017967:Zinc Compounds / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D004337:Drug Carriers; D005456:Fluorescent Dyes; D034741:RNA, Small Interfering; D013440:Sulfides; D017967:Zinc Compounds; C031238:zinc sulfide