title: Recipient and donor risk factors for surgical complications following kidney transplantation.
abstract: OBJECTIVE
  The aim of this study was to evaluate recipient and donor risk factors that are related to surgical complications after renal transplantation.
  
  
  METHODS
  In total, 419 kidney transplantations were analysed with regard to the influence of recipient and donor risk factors on the main postoperative surgical complications.
  
  
  RESULTS
  The mean follow-up for the entire group was 72.8 months (± 54.2 SD). Vascular complications were independently associated with donor age; and urological complications with recipient age >65 years and cyclosporine rather than tacrolimus therapy. Wound complications were independently associated with recipient age, preoperative dialysis time, recipient body mass index (BMI) and cyclosporine rather than tacrolimus therapy. Collections were independently associated with retransplantation, type 2 diabetes mellitus and wound complications. Overall surgical complications were associated with donor age and delayed graft function. In terms of severity, grade I complications were independently associated with recipient age and surgical revision, grade II with recipient age >50 years, grade III with recipient BMI, and grade IV with donor age.
  
  
  CONCLUSIONS
  Recipient characteristics are the primary determinants of wound, urological and minor (Clavien grades I, II and III) complications; however, graft or donor characteristics are the primary risk factors for vascular, overall and major (Clavien grade IV) surgical complications.
authors: Department of Urology, University of Navarra Clinic, Pamplona, Spain. jfbarba@unav.es
authors: Javier
authors: J
authors: Barba
authors: Ruben
authors: R
authors: Algarra
authors: Luis
authors: L
authors: Romero
authors: Antonio
authors: A
authors: Tienza
authors: Jose Maria
authors: JM
authors: Velis
authors: Jose Enrique
authors: JE
authors: Robles
authors: Juan Javier
authors: JJ
authors: Zudaire
authors: Ignacio
authors: I
authors: Pascual
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D015992:Body Mass Index; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006869:Hydronephrosis / Q000453:epidemiology; D007166:Immunosuppressive Agents; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D019106:Postoperative Hemorrhage / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology; D014019:Tissue Donors; D014180:Transplantation
chemical_list: D007166:Immunosuppressive Agents