title: Prevalence and antimicrobial susceptibility of Ureaplasma urealyticum and Mycoplasma hominis in a population of Italian and immigrant outpatients.
abstract: Ureaplasma urealyticum and Mycoplasma hominis are associated with non-gonococcal urethritis, increased risk of recurrent miscarriage, infertility and pelvic inflammatory disease. Migration flows from other countries change the local epidemiological profile of infectious diseases of patients treated by general practitioners and hospital doctors. Few studies have evaluated this ever-changing issue in the Italian population. The aim of this study was to assess possible differences in prevalence and antimicrobial susceptibility of U. urealyticum and M. hominis in a population of 433 Italian and immigrant outpatients by means of the commercially available MYCOFAST(®) Screening EvolutioN 3 Kit. Prevalence of positive samples was 44.5% in Italian patients and 53.4% in immigrants. Samples positive for U. urealyticum and total isolates were more frequent in African patients: U. urealyticum, 51.5% vs 33.3%; Yates-corrected chi-square=3.98; p=0.046; total isolates, 54.5% vs 34.3%; Yates-corrected chi-square=4.45; p=0.035. Among samples positive for U. urealyticum, 66.4% were resistant to ciprofloxacin, whereas 27.6% to ofloxacin. In M. hominis isolates, 66.7% were resistant to both azythromycin and roxythromycin. Our study showed how prevalence of genital mycoplasmas and antibiotic resistance profiles change in relation to the country of origin. Therefore, surveillance is critical for the early cure and prevention of the occurrence of resistant strains.
authors: Microbiology Section, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy.
authors: Christian
authors: C
authors: Leli
authors: Antonella
authors: A
authors: Mencacci
authors: Jessica Concetta
authors: JC
authors: Bombaci
authors: Francesco
authors: F
authors: D'Alò
authors: Senia
authors: S
authors: Farinelli
authors: Mariolina
authors: M
authors: Vitali
authors: Paolo
authors: P
authors: Montagna
authors: Cristiana
authors: C
authors: Bietolini
authors: Marta
authors: M
authors: Meucci
authors: Stefano
authors: S
authors: Perito
authors: Francesco
authors: F
authors: Bistoni
mesh_terms: D000293:Adolescent; D000328:Adult; D000349:Africa / Q000208:ethnology; D000368:Aged; D000369:Aged, 80 and over; D001208:Asia / Q000208:ethnology; D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology; D004352:Drug Resistance, Microbial; D054242:Emigrants and Immigrants / Q000706:statistics & numerical data*; D005061:Europe, Eastern / Q000208:ethnology; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009175:Mycoplasma Infections / Q000453:epidemiology*; D019535:Mycoplasma hominis / Q000187:drug effects / Q000302:isolation & purification*; D010045:Outpatients / Q000706:statistics & numerical data*; D015995:Prevalence; D013020:South America / Q000208:ethnology; D016869:Ureaplasma Infections / Q000453:epidemiology* / Q000382:microbiology; D016990:Ureaplasma urealyticum / Q000187:drug effects / Q000302:isolation & purification*; D014526:Urethritis / Q000453:epidemiology* / Q000382:microbiology; D002575:Uterine Cervicitis / Q000453:epidemiology* / Q000382:microbiology; D055815:Young Adult