title: [A rare pulmonary lesion association].
abstract: BACKGROUND
  Pulmonary amyloidoma or nodular amyloidosis is a localized form of amyloidosis, which can mimic a bronchopulmonary carcinoma. This form of amyloidosis may be associated to an infectious, a systemic disease or a lymphoma.
  
  
  METHODS
  We describe the case of a 36-year-old patient whose past medical history was consistent for a diabetes mellitus and a hypothyroidism treated by medical treatment. The patient presented a Gougerot-Sjögren syndrome and was explored for non-specific respiratory symptoms. Physical examination was normal. Laboratory tests revealed a monoclonal pic of immunoglobulin. Radiologic findings showed bilateral pulmonary nodules associated to mediastinal lymph nodes. A pulmonary biopsy was performed. Histologic examination revealed a tumoral nodule containing an abundant eosinophilic material, which was acellular and surrounded by a dense lymphomatous infiltrate destroying the pulmonary parenchyma. Histochemical and immunohistochemical study revealed an association of a nodular pulmonary amyloidosis with a MAT pulmonary lymphoma complicating a Gougerot-Sjögren syndrome.
  
  
  CONCLUSIONS
  The association of MALT pulmonary lymphoma and localized amyloidosis is rarely observed in case of Gougerot-Sjögren syndrome. The pathogenesis of this association remains unknown and the management non-consensual because of the rarity of the cases reported. Whereas, it appears that localized amyloidosis associated to a MALT lymphoma seems to have a better prognosis than a disseminated amyloidosis.
authors: Service d'Anatomie Pathologique, Hôpital Abderrahman Mami, Ariana, Tunisie. mlika.zorgati.mona@hotmail.com
authors: M
authors: M
authors: Mlika
authors: A
authors: A
authors: Ayadi-Kaddour
authors: A
authors: A
authors: Marghli
authors: I
authors: I
authors: Ridène
authors: S
authors: S
authors: Maalej
authors: F
authors: F
authors: El Mezni
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology*; D008175:Lung Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D013902:Radiography, Thoracic; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging