title: Aranorosin circumvents arbekacin-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2″).
authors: Graduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan.
authors: Takuya
authors: T
authors: Suga
authors: Takahiro
authors: T
authors: Ishii
authors: Masato
authors: M
authors: Iwatsuki
authors: Tsuyoshi
authors: T
authors: Yamamoto
authors: Kenichi
authors: K
authors: Nonaka
authors: Rokuro
authors: R
authors: Masuma
authors: Hidehito
authors: H
authors: Matsui
authors: Hideaki
authors: H
authors: Hanaki
authors: Satoshi
authors: S
authors: Omura
authors: Kazuro
authors: K
authors: Shiomi
mesh_terms: D000123:Acetyltransferases / Q000037:antagonists & inhibitors*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003982:Dibekacin / Q000031:analogs & derivatives* / Q000494:pharmacology; D024881:Drug Resistance, Bacterial / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005663:Furans / Q000494:pharmacology; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000037:antagonists & inhibitors*
chemical_list: D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors; D005663:Furans; C058281:aranorosin; D003982:Dibekacin; C108453:6'-aminoglycoside acetyltransferase-2''-aminoglycoside phosphotransferase; D000123:Acetyltransferases; D017853:Phosphotransferases (Alcohol Group Acceptor); C031986:arbekacin