title: Exocytosis of peptide functionalized gold nanoparticles in endothelial cells.
abstract: We present the exocytosis profile of two types of peptide-coated nanoparticles, which have similar charge and size but different functionality. While one kind of particles appears to progressively exocytose, the other one has a more complex profile, suggesting that some of the particles are re-uptaken by the cells. Both types of particles retain their colloidal stability after exocytosis.
authors: Institute for Life Sciences and Physics and Astronomy, Faculty of Physical and Applied Sciences, Highfield, University of Southampton, Southampton, UKSO17 1BJ.
authors: Dorota
authors: D
authors: Bartczak
authors: Simone
authors: S
authors: Nitti
authors: Timothy M
authors: TM
authors: Millar
authors: Antonios G
authors: AG
authors: Kanaras
mesh_terms: D000595:Amino Acid Sequence; D042783:Endothelial Cells / Q000166:cytology / Q000378:metabolism; D005026:Ethylene Glycols / Q000737:chemistry; D005089:Exocytosis; D006046:Gold / Q000737:chemistry*; D061307:Human Umbilical Vein Endothelial Cells; D006801:Humans; D008027:Light; D053768:Metal Nanoparticles / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry* / Q000378:metabolism; D012542:Scattering, Radiation
chemical_list: D005026:Ethylene Glycols; D010455:Peptides; C077067:hexaethylene glycol; D006046:Gold