title: Synthesis of branched PEG brushes hybrid hydrophilic magnetic nanoparticles for the selective enrichment of N-linked glycopeptides.
abstract: Hybrid Fe(3)O(4)@SiO(2)@PEG-Maltose MNPs were synthesized by SI-ATRP of branched PEG brushes on the surface and subsequent functionalization with hydrophilic maltose group, and the multifunctional materials were utilized for selective enrichment of N-linked glycopeptides from biological samples with high specifity, high sensitivity, and large binding capacity.
authors: CAS Key Laboratory of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Dalian 116023, China.
authors: Zhichao
authors: Z
authors: Xiong
authors: Liang
authors: L
authors: Zhao
authors: Fangjun
authors: F
authors: Wang
authors: Jun
authors: J
authors: Zhu
authors: Hongqiang
authors: H
authors: Qin
authors: Ren'an
authors: R
authors: Wu
authors: Weibing
authors: W
authors: Zhang
authors: Hanfa
authors: H
authors: Zou
mesh_terms: D052203:Ferrosoferric Oxide / Q000737:chemistry; D006020:Glycopeptides / Q000737:chemistry / Q000302:isolation & purification*; D006031:Glycosylation; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D007074:Immunoglobulin G / Q000737:chemistry; D058185:Magnetite Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008320:Maltose / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D012680:Sensitivity and Specificity; D012822:Silicon Dioxide / Q000737:chemistry*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D006020:Glycopeptides; D007074:Immunoglobulin G; D058185:Magnetite Nanoparticles; D011092:Polyethylene Glycols; D008320:Maltose; D012822:Silicon Dioxide; D052203:Ferrosoferric Oxide