title: Itch and the brain.
abstract: The sensation of itch - defined as unpleasant sensation inducing the urge to scratch - is processed by a network of different brain regions contributing to the encoding of sensory, emotional, attention-dependent, cognitive-evaluative and motivational patterns. Patients with atopic eczema show different activation patterns and kinetics compared to healthy volunteers. This review summarizes current studies investigating itch in the brain.
authors: Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02129, USA. pfab@nmr.mgh.harvard.edu
authors: F
authors: F
authors: Pfab
authors: M
authors: M
authors: Valet
authors: V
authors: V
authors: Napadow
authors: T-R
authors: TR
authors: Tölle
authors: H
authors: H
authors: Behrendt
authors: J
authors: J
authors: Ring
authors: U
authors: U
authors: Darsow
mesh_terms: D001921:Brain / Q000033:anatomy & histology / Q000000981:diagnostic imaging* / Q000378:metabolism; D003876:Dermatitis, Atopic / Q000000981:diagnostic imaging / Q000378:metabolism; D006632:Histamine / Q000378:metabolism; D006801:Humans; D008279:Magnetic Resonance Imaging; D059906:Neuroimaging; D049268:Positron-Emission Tomography; D011537:Pruritus / Q000000981:diagnostic imaging* / Q000378:metabolism; D013696:Temperature
chemical_list: D006632:Histamine