title: A case of gastric cancer after living donor liver transplantation.
abstract: BACKGROUND
  As newer immunosuppressive regimens have steadily reduced in the incidence of acute rejection and have extended the life expectancy of allograft recipients, posttransplant de novo malignancies have become an important cause of death in cadaveric donor transplantation. Also, according with the recent accumulation of living donor liver transplantation (LDLT), the number of posttransplant recipients with de novo malignancy will be anticipated to increase.
  
  
  METHODS
  A 60 year-old man underwent LDLT for hepatitis C virus-related cirrhosis with hepatocellular carcinoma. Thirty months after LDLT, he was found to have gastric cancer by upper gastrointestinal endoscopy. He underwent segmental gastrectomy with lymph node dissection. Histopathological examination of the explanted stomach revealed poorly differentiated adenocarcinoma with subserosal invasion in the gastric wall and perigastric lymph node metastasis. Three years and eight months after the gastric surgery, the patient is alive with no recurrence of gastric cancer or HCC under no adjuvant chemotherapy.
  
  
  CONCLUSIONS
  Considering that early detection is the only key in curing cancer in general, we should make effort to detect cancer in their early stage, especially in case of LDLT recipients.
authors: Department of General and Gastroenterological Surgery, Osaka Medical College Hospital, Japan. 0315shimizu@gmail.com
authors: Tetsunosuke
authors: T
authors: Shimizu
authors: Michihiro
authors: M
authors: Hayashi
authors: Yoshihiro
authors: Y
authors: Inoue
authors: Koji
authors: K
authors: Komeda
authors: Mitsuhiro
authors: M
authors: Asakuma
authors: Fumitoshi
authors: F
authors: Hirokawa
authors: Yoshiharu
authors: Y
authors: Miyamoto
authors: Nobuhiko
authors: N
authors: Tanigawa
authors: Kazuhisa
authors: K
authors: Uchiyama
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006528:Carcinoma, Hepatocellular / Q000601:surgery; D005743:Gastrectomy; D006526:Hepatitis C / Q000601:surgery; D006801:Humans; D008103:Liver Cirrhosis / Q000601:surgery; D008113:Liver Neoplasms / Q000601:surgery; D016031:Liver Transplantation; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000175:diagnosis*; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000601:surgery