title: Gastric MALT lymphoma treated with primary radiotherapy in the setting of autoimmune disease.
abstract: Autoimmune and microbial-induced immune reactions are associated with lymphomagenesis, particularly of extranodal marginal zone B-cell lymphomas. This report presents a case of Helicobacter pylori-negative gastric extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) in the setting of Sjögren syndrome and Hashimoto thyroiditis treated with primary involved-field radiotherapy. This report describes etiologic data, diagnostic and treatment considerations, and sophisticated radiation therapy techniques aimed at reducing long-term toxicity in this indolent disease.
authors: Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. CCPinnix@mdanderson.org
authors: Chelsea C
authors: CC
authors: Pinnix
authors: Valerie
authors: V
authors: Reed
authors: Bouthaina
authors: B
authors: Dabaja
mesh_terms: D001327:Autoimmune Diseases / Q000150:complications; D005260:Female; D056973:Four-Dimensional Computed Tomography; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications / Q000175:diagnosis / Q000532:radiotherapy*; D008875:Middle Aged; D050397:Radiotherapy, Intensity-Modulated; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000532:radiotherapy*