title: Experimental study of bone response to hydroxyapatite coating implants: bone-implant contact and removal torque test.
abstract: OBJECTIVE
  The objective of this study was to evaluate the early osseointegration of hydroxyapatite (HA)-coated implant.
  
  
  METHODS
  Twelve adult male miniature pigs were used in this study. The removal torque of implants placed in the tibia of miniature pigs was measured. For implants placed in the mandible, histomorphometric evaluation was performed for the evaluation of the bone-implant contact (BIC) ratio.
  
  
  RESULTS
  After 4, 8, and 12 weeks, removal torque values were increased. Among the 3 groups, the HA-coated group showed the highest values (P < .05). At 4 and 8 weeks, the BIC ratio of HA was significantly higher than that of resorbable blast medium or sand blasted with alumina and acid etched (P < .05).
  
  
  CONCLUSIONS
  It was concluded that HA-coated implants are relatively favorable in early loading stages.
authors: Department of Biomedical Engineering, School of Medicine, Pusan National University, South Korea.
authors: Tae-Gwan
authors: TG
authors: Eom
authors: Gyeo-Rok
authors: GR
authors: Jeon
authors: Chang-Mo
authors: CM
authors: Jeong
authors: Young-Kyun
authors: YK
authors: Kim
authors: Su-Gwan
authors: SG
authors: Kim
authors: In-Hee
authors: IH
authors: Cho
authors: Yong-Seok
authors: YS
authors: Cho
authors: Ji-Su
authors: JS
authors: Oh
mesh_terms: D000134:Acid Etching, Dental; D000818:Animals; D020099:Coated Materials, Biocompatible / Q000494:pharmacology*; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D020878:Device Removal; D017886:Durapatite / Q000494:pharmacology*; D008297:Male; D008334:Mandible / Q000601:surgery; D008422:Materials Testing; D016348:Osseointegration / Q000187:drug effects*; D018709:Statistics, Nonparametric; D013499:Surface Properties; D013552:Swine; D013556:Swine, Miniature; D013977:Tibia / Q000601:surgery; D019415:Torque
chemical_list: D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D017886:Durapatite