title: COPD and depressive symptoms: findings from the Guangzhou Biobank Cohort Study.
abstract: BACKGROUND
  Chronic obstructive pulmonary disease (COPD) co-exists with depression, but important questions remain about the determinants of this association.
  
  
  OBJECTIVE
  We examined the association of depressive symptoms with three aspects of COPD: self-reports of physician-diagnosed COPD, chronic respiratory symptoms, and airway obstruction.
  
  
  METHODS
  We used data from the Guangzhou Biobank Cohort Study (n = 7,995). Airway obstruction was assessed by spirometry. A score ≥4 on the 15-item Geriatric Depression Scale was used as a cutoff for depressive symptoms.
  
  
  RESULTS
  Self-reported COPD was positively associated with depressive symptoms but airway obstruction was not. Compared to those free of both respiratory symptoms and airway obstruction those reporting respiratory symptoms were more likely to have depressive symptoms regardless of whether they had obstruction or not.
  
  
  CONCLUSIONS
  In this Chinese population, a self-reported physician diagnosis of COPD and symptom perception, but not airway obstruction, appeared as main determinants of depressive symptoms.
authors: Mannheim Institute of Public Health, Social and Preventive Medicine, Heidelberg University, Mannheim, Germany.
authors: Adrian
authors: A
authors: Loerbroks
authors: Chao Qiang
authors: CQ
authors: Jiang
authors: G Neil
authors: GN
authors: Thomas
authors: Peymané
authors: P
authors: Adab
authors: Wei Sen
authors: WS
authors: Zhang
authors: Kin-Bong Hubert
authors: KB
authors: Lam
authors: Jos A
authors: JA
authors: Bosch
authors: Kar Keung
authors: KK
authors: Cheng
authors: Tai Hing
authors: TH
authors: Lam
mesh_terms: D000368:Aged; D002681:China; D015331:Cohort Studies; D003863:Depression / Q000150:complications / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011594:Psychometrics; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000453:epidemiology / Q000523:psychology*; D011788:Quality of Life; D057566:Self Report; D012907:Smoking