title: Clinical experience with complications of hand rejuvenation.
abstract: OBJECTIVE
  Prominent signs of ageing of the hands have recently been treated with permanent or longer-lasting injectable dermal fillers. However, few previous studies have described the long-term complications of such hand rejuvenation. The purpose of our report was to share our experience of 15 cases with long-term complications following hand rejuvenation using various medical fillers.
  
  
  METHODS
  We performed a retrospective review of the management of 15 patients who presented with complications from the injection of synthetic fillers for hand rejuvenation at a tertiary medical centre over a period of 10 years from March 2002 to January 2011.
  
  
  RESULTS
  Injected materials included polymethylmethacrylate (PMMA) microsphere filler, calcium hydroxyapatite filler, hyaluronic acid filler, poly-l-lactic acid (PLLA) filler and other medical fillers. Of the total study sample of 15 patients, nine underwent surgical excision, six patients with a history of PMMA or PLLA filler injection received intralesional steroid therapy and three patients with a history of hyaluronic acid filler injection received injection therapy using hyaluronidase.
  
  
  CONCLUSIONS
  Hand rejuvenation complications can be successfully treated according to our proposed algorithm.
authors: Department of Plastic and Reconstructive Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University, School of Medicine, Seoul, Republic of Korea.
authors: Tae Hwan
authors: TH
authors: Park
authors: Kwan Koo
authors: KK
authors: Yeo
authors: Sang Won
authors: SW
authors: Seo
authors: June-Kyu
authors: JK
authors: Kim
authors: Ji Hwan
authors: JH
authors: Lee
authors: Ji Hae
authors: JH
authors: Park
authors: Dong Kyun
authors: DK
authors: Rah
authors: Choong Hyun
authors: CH
authors: Chang
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D003131:Combined Modality Therapy; D003357:Cosmetic Techniques; D017886:Durapatite / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D006225:Hand; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000009:adverse effects; D007271:Injections, Intradermal / Q000009:adverse effects*; D019344:Lactic Acid / Q000008:administration & dosage / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011091:Polyesters; D011108:Polymers / Q000008:administration & dosage / Q000009:adverse effects; D019904:Polymethyl Methacrylate / Q000008:administration & dosage / Q000009:adverse effects; D011183:Postoperative Complications / Q000453:epidemiology*; D012060:Rejuvenation; D012189:Retrospective Studies; D015595:Skin Aging; D016896:Treatment Outcome
chemical_list: D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide); D006820:Hyaluronic Acid; D019904:Polymethyl Methacrylate; D017886:Durapatite