title: Perceived and actual obesity in childhood and adolescence and risk of adult depression.
abstract: BACKGROUND
  Obesity in childhood and adolescence has important health consequences, but its relation to risk of adult depression remains uncertain.
  
  
  OBJECTIVE
  To examine the effect of perceived and actual obesity during childhood and adolescence on prevalence and incidence of adult depression risk.
  
  
  METHODS
  Cohort study of 91,798 female registered nurses followed longitudinally for 12 years.
  
  
  RESULTS
  As compared with lean women of the same age, women in the two highest categories of body shape at age 10 had both higher prevalence (OR=2.59, 95% CI 1.46 to 4.61) and incidence (OR=2.01, 95% CI 1.08 to 3.71) of depression. Similar results were obtained for body shape at age 20 (OR=3.43 for prevalence and OR=2.03 for incidence) and for body mass index (BMI) at age 18 (OR=2.92 for BMI ≥ 40 kg/m(2)). These associations remained significant after adjustment for multiple confounders.
  
  
  CONCLUSIONS
  These results indicate that childhood-adolescence obesity is a strong and independent risk factor for adult depression.
authors: Department of Clinical Sciences, University of Las Palmas de Gran Canaria, P.O. Box 550, Las Palmas de Gran Canaria 35008, Spain. asanchez@dcc.ulpgc.es
authors: Almudena
authors: A
authors: Sanchez-Villegas
authors: Alison E
authors: AE
authors: Field
authors: Eilis J
authors: EJ
authors: O'Reilly
authors: Maurizio
authors: M
authors: Fava
authors: Steven
authors: S
authors: Gortmaker
authors: Ichiro
authors: I
authors: Kawachi
authors: Alberto
authors: A
authors: Ascherio
mesh_terms: D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D003863:Depression / Q000453:epidemiology* / Q000209:etiology / Q000523:psychology; D005260:Female; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008137:Longitudinal Studies; D009765:Obesity / Q000453:epidemiology / Q000523:psychology*; D010465:Perception; D015995:Prevalence; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014481:United States / Q000453:epidemiology; D055815:Young Adult