title: [The implementation of computer model in research of dynamics of proliferation of cells of thyroid gland follicle].
abstract: The article deals with the results of computational experiments in research of dynamics of proliferation of cells of thyroid gland follicle in normal condition and in the case of malignant neoplasm. The model studies demonstrated that the chronic increase of parameter of proliferation of cells of thyroid gland follicle results in abnormal behavior of numbers of cell cenosis of thyroid gland follicle. The stationary state interrupts, the auto-oscillations occur with transition to irregular oscillations with unpredictable cell proliferation and further to the "black hole" effect. It is demonstrated that the present medical biologic experimental data and theory propositions concerning the structural functional organization of thyroid gland on cell level permit to develop mathematical models for quantitative analysis of numbers of cell cenosis of thyroid gland follicle in normal conditions. The technique of modeling of regulative mechanisms of living systems and equations of cell cenosis regulations was used
authors: A A
authors: AA
authors: Abduvaliev
authors: M S
authors: MS
authors: Gil'dieva
authors: B N
authors: BN
authors: Khidirov
authors: M
authors: M
authors: Saĭdalieva
authors: A A
authors: AA
authors: Khasanov
authors: Sh N
authors: ShN
authors: Musaeva
authors: T S
authors: TS
authors: Saatov
mesh_terms: D000818:Animals; D049109:Cell Proliferation; D003198:Computer Simulation; D006801:Humans; D008954:Models, Biological; D013961:Thyroid Gland / Q000166:cytology* / Q000378:metabolism*