title: Prognostic factors for treatment outcomes in transient tachypnea of the newborn.
abstract: BACKGROUND
  Transient tachypnea of the newborn (TTN) is a clinical syndrome associated with respiratory distress usually seen shortly after delivery in infants. This study aims to determine the risk factors predicting treatment outcomes in infants with TTN.
  
  
  METHODS
  Data from 236 infants diagnosed with TTN during the study period were evaluated retrospectively. Logistic regression analyses were performed to select significant risk factor for prognosis (prolonged oxygen therapy, application of mechanical ventilator, and prolonged hospital stay) of TTN among components of clinical variables.
  
  
  RESULTS
  Of the 236 TTN infants, 111 (47.0%) infants were delivered via cesarean section (CS) without labor, 29 (12.3%) infants were delivered via CS with labor, and 96 (40.7%) were delivered via vaginal birth. Lower Apgar score at 1 min (OR: 3.03; 95%CI: 1.25-7.36) and lower umbilical artery pH (OR: 4.00; 95%CI 1.55-10.49) were associated with a significantly increased risk for mechanical ventilator care. Also, late-preterm delivery (OR: 4.70; 95%CI: 2.11-10.49) was independently associated with risk of prolonged duration of hospital stay.
  
  
  CONCLUSIONS
  Late-preterm delivery, lower initial umbilical artery pH (<7.25), and lower Apgar score at 1 min were independently associated with poor prognostic treatment outcomes in infants with TTN.
authors: Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, , Seoul, Korea.
authors: Seon-Yeong
authors: SY
authors: Bak
authors: Youn-Ho
authors: YH
authors: Shin
authors: Ji-Hyun
authors: JH
authors: Jeon
authors: Kyu-Hee
authors: KH
authors: Park
authors: Jin-Hee
authors: JH
authors: Kang
authors: Dong-Hyun
authors: DH
authors: Cha
authors: Man-Yong
authors: MY
authors: Han
authors: Heui-Seung
authors: HS
authors: Jo
authors: Kyu-Hyung
authors: KH
authors: Lee
authors: Cho-Ae
authors: CA
authors: Lee
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods*; D015994:Incidence; D007231:Infant, Newborn; D007902:Length of Stay / Q000639:trends; D008297:Male; D011379:Prognosis; D056910:Republic of Korea / Q000453:epidemiology; D012121:Respiration, Artificial / Q000379:methods*; D012127:Respiratory Distress Syndrome, Newborn / Q000150:complications* / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D059245:Transient Tachypnea of the Newborn / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy