title: [Kidney and bone update : the 5-year history and future of CKD-MBD. Mineral and bone disorder in kidney transplant recipients].
abstract: CKD-MBD in kidney transplant recipients (KTRs) is multifactorial. Although it is characterized by drastic changes in laboratory parameters just after transplantation and uncoupling bone mineral metabolism induced by immunosuppressive drugs and progressive renal dysfunction, its pathophysiology starts before transplantation such that CKD-MBD in dialysis patients arises from predialysis CKD stages. The legacy effect of CKD-MBD gained during dialysis period is rather remarkable, and thus a long-term management of CKD-MBD as a continuum is essential.
authors: Hyogo Prefectural Nishinomiya Hospital Research and Medical Center for Kidney Disease and Transplantation, Japan.
authors: Naohiko
authors: N
authors: Fujii
authors: Ayako
authors: A
authors: Okuno
authors: Sayoko
authors: S
authors: Yonemoto
authors: Kenji
authors: K
authors: Nishimura
authors: Hidefumi
authors: H
authors: Kishikawa
authors: Yasuji
authors: Y
authors: Ichikawa
mesh_terms: D001851:Bone Diseases, Metabolic / Q000209:etiology* / Q000378:metabolism; D002908:Chronic Disease; D003956:Dialysis / Q000009:adverse effects; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000209:etiology; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007674:Kidney Diseases / Q000150:complications / Q000378:metabolism / Q000628:therapy*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008903:Minerals / Q000378:metabolism*; D010024:Osteoporosis / Q000209:etiology
chemical_list: D007166:Immunosuppressive Agents; D008903:Minerals