title: Exocrine pancreas cancer and thromboembolic events: a systematic literature review.
abstract: Exocrine pancreas cancer continues to represent a significant therapeutic challenge, with high rates of mortality and morbidity, including from thromboembolic events, which have long been described as a frequent complication of the disease. This article provides a systematic and comprehensive review of the literature to address the clinical and pathologic features recognized in pancreas cancer pertaining to thrombosis, and to discuss ongoing investigations of prophylactic anticoagulation in the hopes of improving disease-related outcomes.
authors: Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
authors: Andrew S
authors: AS
authors: Epstein
authors: Eileen M
authors: EM
authors: O'Reilly
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D006801:Humans; D015994:Incidence; D046790:Pancreas, Exocrine / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000188:drug therapy; D012307:Risk Factors; D013923:Thromboembolism / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics / Q000517:prevention & control; D013927:Thrombosis / Q000209:etiology / Q000235:genetics / Q000517:prevention & control
chemical_list: D000925:Anticoagulants