title: Impact of six-week viral load on mortality in HIV-infected Zimbabwean infants.
abstract: Among 453 untreated HIV-infected Zimbabwean infants, 6-week viral load was the only infant factor that independently predicted mortality. Infants with viral load ≥ 1.59 million copies/mL (cohort median) had 3-fold increased mortality through 6 months (hazard ratio 3.07 [95% confidence interval: 2.16, 4.38]; P < 0.001) and 2-fold increased mortality through 12 months (hazard ratio 2.03 [95% confidence interval: 1.41, 2.91]; P < 0.001], compared with infants with viral load below the median.
authors: Zvitambo Project, Harare, Zimbabwe.
authors: Kuda
authors: K
authors: Mutasa
authors: Robert
authors: R
authors: Ntozini
authors: Andrew
authors: A
authors: Prendergast
authors: Peter
authors: P
authors: Iliff
authors: Sandra
authors: S
authors: Rukobo
authors: Lawrence H
authors: LH
authors: Moulton
authors: Brian J
authors: BJ
authors: Ward
authors: Jean H
authors: JH
authors: Humphrey
mesh_terms: D016009:Chi-Square Distribution; D015331:Cohort Studies; D018450:Disease Progression; D005260:Female; D015658:HIV Infections / Q000401:mortality* / Q000635:transmission / Q000821:virology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008297:Male; D019562:Viral Load / Q000706:statistics & numerical data*; D015030:Zimbabwe / Q000453:epidemiology