title: Is there an increased risk of hip fracture in Parkinson's disease? A nationwide inpatient sample.
abstract: OBJECTIVE
  The aim of this study was to determine whether people with Parkinson's disease (PD) are overrepresented in a national cohort of hip-fracture admissions.
  
  
  BACKGROUND
  Frequent falls, combined with a higher rate of osteoporosis in people with PD, should lead to an increased risk of hip fracture.
  
  
  METHODS
  This work was a retrospective cohort analysis from the Nationwide Inpatient Sample from 1988 to 2007, a stratified sample of 20% of U.S. hospital admissions. Admissions with a primary diagnosis of acute hip fracture were identified, as was a subset with a secondary diagnosis of PD.
  
  
  RESULTS
  A total of 3.63% of 1,066,404 hip-fracture admissions had PD. When compared to the population of prevalence among patients with hip fracture, the prevalence of PD was up to 4.48 times (95% confidence interval [CI]: 4.46, 4.49) more than predicted, and when adjusted for gender and age, it was 4.02 (95% CI: 4.00, 4.03).
  
  
  CONCLUSIONS
  In this 20-year nationwide sample of hip fractures, patients with PD were overrepresented by a factor of 4.
authors: Department of Internal Medicine, Division of Endocrinology, Metabolism, and Genetics, University of Kansas Medical Center, Kansas City, Kansas 66160, USA. rbhattacharya@kumc.edu
authors: Rajib K
authors: RK
authors: Bhattacharya
authors: Richard M
authors: RM
authors: Dubinsky
authors: Sue Min
authors: SM
authors: Lai
authors: Hilary
authors: H
authors: Dubinsky
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002170:Canada / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D006620:Hip Fractures / Q000150:complications / Q000453:epidemiology*; D006760:Hospitalization; D006801:Humans; D007297:Inpatients; D008297:Male; D010300:Parkinson Disease / Q000150:complications / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D014481:United States / Q000453:epidemiology