title: Preparation of controlled nano-MgO and investigation of its bactericidal properties.
abstract: Nano-MgO is a good bactericide but with strong alkalinity in water due to its rapid hydrolysis. To control its hydrolysis rate and keep its bactericidal properties, we synthesized nano-MgO microspheres using chitosan-alginate system in this study. The synthesized nano-MgO release-controlled microspheres (nMgO-RCM) were with 0.98-1.20mm of particle sizes. Also, their embedding ratio and loading percentage was 63.52% and 12.27%, respectively. Based on the characterization results, nano-MgO was only observed on surface of the nMgO-RCM. Its release rate from the nMgO-RCM could be controlled by the chitosan-alginate system, and the observed rate constant (k(obs)) increased from 0.0289 h(-1) to 0.0358 h(-1) with the increment of the dosage from 10 mg L(-1) to 80 mg L(-1). Furthermore, the nMgO-RCM could maintain pH value lower than 8.5 and colony counts less than 20 CFU mL(-1) for at least 120 h.
authors: Laboratory of Agro-Waste to Resource/Scientific Observing and Experimental Station of Dali, Institute of Agro-Environmental Protection, Ministry of Agriculture, Tianjin 300191, PR China.
authors: Keqiang
authors: K
authors: Zhang
authors: Yi
authors: Y
authors: An
authors: Lei
authors: L
authors: Zhang
authors: Qi
authors: Q
authors: Dong
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000633:toxicity*; D048271:Chitosan / Q000031:analogs & derivatives / Q000737:chemistry; D008277:Magnesium Oxide / Q000737:chemistry / Q000633:toxicity*; D008863:Microspheres; D049329:Nanostructures / Q000737:chemistry / Q000633:toxicity*
chemical_list: D000900:Anti-Bacterial Agents; D008277:Magnesium Oxide; D048271:Chitosan