title: The future of HIV treatment.
abstract: Antiretroviral therapy has transformed the management of HIV-infected individuals over the past quarter century. However, important challenges remain. These include attempts to eradicate HIV from reservoirs within the body, thereby eliminating the need for lifetime therapy. In addition, improvements in drug development, clinical trial, and regulatory pathways are necessary to expeditiously evaluate novel therapeutic regimens and strategies. Antiretroviral drug scarcity remains a major problem in underserved populations worldwide, and partnerships among pharmaceutical companies, academic investigators, and both governmental and nongovernmental agencies are necessary to improve access to these life-saving regimens.
authors: Department of Medicine, Massachusetts General Hospital, Boston MA, USA. hirsch.martin@mgh.harvard.edu
authors: Martin S
authors: MS
authors: Hirsch
authors: Daniel R
authors: DR
authors: Kuritzkes
mesh_terms: D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000191:economics / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D055808:Drug Discovery / Q000379:methods; D024882:Drug Resistance, Viral; D015507:Drugs, Investigational / Q000191:economics / Q000627:therapeutic use; D015658:HIV Infections / Q000188:drug therapy* / Q000517:prevention & control*; D015497:HIV-1 / Q000187:drug effects; D006801:Humans; D010349:Patient Compliance; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D019380:Anti-HIV Agents; D015507:Drugs, Investigational