title: No ubiquitin anchors and fully RIGged.
abstract: Unanchored chains of ubiquitin have recently been proposed to play a role in signaling. In this issue of Immunity, Jiang et al. (2012) demonstrate that binding of free polyubiquitin to the viral RNA sensors RIG-I and MDA5 leads to their oligomerization and activation.
authors: Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.
authors: Lynn
authors: L
authors: Verstrepen
authors: Rudi
authors: R
authors: Beyaert