title: Preparation of functional benzofurans and indoles via chemoselective intramolecular Wittig reactions.
abstract: A general preparation of new types of benzofurans, benzothiophenes and indoles is realized via chemoselective intramolecular Wittig reactions with the corresponding ester, thioester and amide functionalities using in situ formed phosphorus ylides as key intermediates. The reaction conditions are very mild, and numerous Michael acceptors and commercially available acid chlorides can be applied very efficiently in a one-step procedure.
authors: Department of Chemistry, National Taiwan Normal University, 88, Sec. 4, Tingchow Road, Taipei 11677, Taiwan, ROC.
authors: Yu-Ting
authors: YT
authors: Lee
authors: Yeong-Jiunn
authors: YJ
authors: Jang
authors: Siang-en
authors: SE
authors: Syu
authors: Shu-Chi
authors: SC
authors: Chou
authors: Chia-Jui
authors: CJ
authors: Lee
authors: Wenwei
authors: W
authors: Lin
mesh_terms: D000577:Amides / Q000138:chemical synthesis / Q000737:chemistry; D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D002712:Chlorides / Q000138:chemical synthesis / Q000737:chemistry; D004952:Esters / Q000138:chemical synthesis / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D009943:Organophosphorus Compounds / Q000138:chemical synthesis / Q000737:chemistry; D013876:Thiophenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000577:Amides; D001572:Benzofurans; D002712:Chlorides; D004952:Esters; D007211:Indoles; D009943:Organophosphorus Compounds; D013876:Thiophenes; C088015:benzothiophene