title: Correlation of narrow band imaging with magnifying colonoscopy and histology in colorectal tumors.
abstract: OBJECTIVE
  Narrow band imaging (NBI) is a new technique that uses optical filters for imaging of mucosal morphology. The aim of this study was to correlate findings of NBI with magnifying colonoscopy and histology for prediction of neoplastic colorectal lesion.
  
  
  METHODS
  Between September 2005 and December 2007, 107 colon polyps from 68 patients were detected by conventional colonoscopy and subsequently evaluated by NBI with magnifying colonoscopy and analyzed for a pit pattern and a capillary pattern. More analysis was done regarding thickness and irregularity of capillary features.
  
  
  RESULTS
  Pit pattern with NBI magnification to discriminate between neoplastic and non-neoplastic lesions had a sensitivity of 88.9% and a specificity of 87.5%; capillary pattern yielded test performance characteristics of 91.9% and 87.5%. In respect of capillary thickness, invisible capillaries were found significantly more often in hyperplastic lesions. All thick capillaries were found in neoplastic polyps, and found significantly more often in carcinomas with submucosal massive invasion (sm-m) (p<0.01). In respect of capillary irregularity, invisible capillaries were found significantly more often in hyperplasic lesions, and severely irregular capillaries were found significantly more often in sm-m lesions (p<0.01).
  
  
  CONCLUSIONS
  Observation of capillary thickness and irregularity by NBI magnification is useful for correlating histological grade with carcinoma, especially with depth of submucosal invasion.
authors: Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
authors: Hee Yong
authors: HY
authors: Yoo
authors: Moon Sung
authors: MS
authors: Lee
authors: Bong Min
authors: BM
authors: Ko
authors: Hee Kyung
authors: HK
authors: Kim
authors: Hyung Su
authors: HS
authors: Ahn
authors: Seung Hyo
authors: SH
authors: Han
authors: Jun Yong
authors: JY
authors: Bae
authors: Seul Ki
authors: SK
authors: Min
authors: Jong Chan
authors: JC
authors: Lee
authors: Chang Beom
authors: CB
authors: Ryu