title: The association between arterial hypertension and rotator cuff tear: the influence on rotator cuff tear sizes.
abstract: BACKGROUND
  This study was conducted to establish whether hypertension increases the risk of occurrence of rotator cuff tear and influences its size.
  
  
  METHODS
  A case-control design was used. We studied 408 consecutive patients (228 men, 180 women) who underwent arthroscopic rotator cuff repair. Tear size was determined during surgery. The control group included 201 individuals. For the study purpose, participants were divided into 2 groups by presence or absence of hypertension. We applied a logistic regression model to investigate if hypertension affects the risk of cuff tear. A multinomial logistic regression model was applied to explore the association between hypertension and tear size. We used the analysis of covariance method to determine if the duration of hypertension influences the severity of the tear; finally, we compared mean duration of antihypertensive therapy in patients with small, large, and massive tears. All analyses were adjusted for age and sex.
  
  
  RESULTS
  Hypertension was associated with a 2-fold higher risk of tear occurrence (odds ratio [OR], 2.05; 95% confidence interval [CI], 41-2.98). No association was detected between hypertension and the probability of a small tear (OR, 0.63, 95% CI, 0.33-1.19). Hypertensive individuals were 2 times more likely to experience large tear (OR, 02.09; 95% CI, 1.39-3.16) and 4 times more likely to experience massive tear (OR, 04.30; 95% CI, 2.44-7.58) than normotensive individuals. Mean duration of antihypertensive therapy significantly increased from small tear (1.08 years) to large tear (3.20 years) to massive tear (6.34 years) patients (analysis of covariance: F((2,403)) = 16.357, P = 1.48 × 10(-7)).
  
  
  CONCLUSIONS
  Our data provide evidence that hypertension is a significant risk factor for the occurrence and severity of rotator cuff tears.
authors: Department of Orthopaedic and Traumatology, University of Rome Sapienza, Rome, Italy. stefcarbone@yahoo.it
authors: Stefano
authors: S
authors: Gumina
authors: Valerio
authors: V
authors: Arceri
authors: Stefano
authors: S
authors: Carbone
authors: Paolo
authors: P
authors: Albino
authors: Daniele
authors: D
authors: Passaretti
authors: Vincenzo
authors: V
authors: Campagna
authors: Corrado
authors: C
authors: Fagnani
authors: Franco
authors: F
authors: Postacchini
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D017006:Rotator Cuff / Q000601:surgery*; D000070636:Rotator Cuff Injuries; D013708:Tendon Injuries / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*