title: Wake-promoting agents: search for next generation modafinil: part IV.
abstract: In search of a next generation molecule to the novel wake promoting agent modafinil, a series of diphenyl ether derived wakefulness enhancing agents (in rat) was developed. From this work, racemic compound 16 was separated into its chiral enantiomers to profile them individually.
authors: Cephalon (France), Paris, France.
authors: Philippe
authors: P
authors: Louvet
authors: Dominique
authors: D
authors: Schweizer
authors: Marie-Edith
authors: ME
authors: Gourdel
authors: Eric
authors: E
authors: Riguet
authors: Christoph
authors: C
authors: Yue
authors: Val R
authors: VR
authors: Marcy
authors: Yin Guo
authors: YG
authors: Lin
authors: John
authors: J
authors: Gruner
authors: Brigitte
authors: B
authors: Lesur
authors: Edward R
authors: ER
authors: Bacon
authors: Sankar
authors: S
authors: Chatterjee
mesh_terms: D000818:Animals; D001559:Benzhydryl Compounds / Q000737:chemistry / Q000494:pharmacology*; D065607:Cytochrome P-450 Enzyme Inhibitors; D055808:Drug Discovery; D006801:Humans; D000077408:Modafinil; D051381:Rats; D014851:Wakefulness / Q000187:drug effects*
chemical_list: D001559:Benzhydryl Compounds; D065607:Cytochrome P-450 Enzyme Inhibitors; D000077408:Modafinil