title: Characterization of the role of calcium in regulating the microtubule-destabilizing activity of MDP25.
abstract: Regulation of cell elongation is important for plant morphogenesis. Many studies have shown that cortical microtubules play crucial roles during cell elongation and that microtubule stability, organization, and dynamics are regulated by microtubule regulatory proteins. Recently, we reported that a novel protein from Arabidopsis, termed microtubule-destabilizing protein 25 (MDP25), functions as a negative regulator of hypocotyl cell elongation. MDP25 destabilizes microtubules and exerts its effect on microtubules as a result of transient elevation of cytosolic calcium levels.
authors: Department of Plant Sciences, State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, China.
authors: Tao
authors: T
authors: Qin
authors: Jiejie
authors: J
authors: Li
authors: Ming
authors: M
authors: Yuan
authors: Tonglin
authors: T
authors: Mao
mesh_terms: D017360:Arabidopsis / Q000187:drug effects / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism*; D020013:Calcium Signaling; D002135:Calcium-Binding Proteins / Q000378:metabolism*; D008869:Microtubule-Associated Proteins / Q000378:metabolism; D008870:Microtubules / Q000187:drug effects / Q000378:metabolism*; D017239:Paclitaxel / Q000494:pharmacology; D058105:Polymerization / Q000187:drug effects
chemical_list: D029681:Arabidopsis Proteins; D002135:Calcium-Binding Proteins; C492901:MAP65-1 protein, Arabidopsis; D008869:Microtubule-Associated Proteins; C521040:PCaP1 protein, Arabidopsis; D017239:Paclitaxel; D002118:Calcium