title: Effect of iron supplementation on development of iron deficiency anemia in breastfed infants.
abstract: This trial aimed to investigate the effect of iron supplementation on the development of iron deficiency anemia. The study encompassed 6-month-old infants who had been exclusively breastfed in the first 4 months of life. Infants in the supplemented group were given 1 mg kg(-1 )day(-1) ferrous sulfate for 6 months starting at 6 months of age. Blood samples were taken at age 12 months. A 3-day-diet was evaluated at 1 year of age. Data of 51 infants in the supplemented and 54 infants in the control group were analyzed. Mean hemoglobin values were similar in the two groups at the age of 12 months. Mean ferritin level of the supplemented group was significantly higher than that of the control. There was a significant positive correlation between dietary iron intake and hemoglobin levels. Nutrition might be more important than iron supplementation in preventing iron deficiency anemia during infancy.
authors: Institute of Child Health, Istanbul University, Istanbul, Turkey. gokcay@superonline.com
authors: Gulbin
authors: G
authors: Gokcay
authors: Tulin
authors: T
authors: Ozden
authors: Zeynep
authors: Z
authors: Karakas
authors: Nalan
authors: N
authors: Karabayir
authors: Ismail
authors: I
authors: Yildiz
authors: Saygin
authors: S
authors: Abali
authors: Yusuf
authors: Y
authors: Sahip
mesh_terms: D000367:Age Factors; D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000453:epidemiology / Q000517:prevention & control*; D001942:Breast Feeding; D019587:Dietary Supplements; D004334:Drug Administration Schedule; D005260:Female; D005293:Ferritins / Q000097:blood; D005500:Follow-Up Studies; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007223:Infant; D007501:Iron / Q000008:administration & dosage*; D000090463:Iron Deficiencies; D008297:Male; D009752:Nutritional Status; D011446:Prospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D014421:Turkey / Q000453:epidemiology
chemical_list: D006454:Hemoglobins; D005293:Ferritins; D007501:Iron