title: Quantitation of first- and second-generation antipsychotics by LC-MS/MS.
abstract: Antipsychotic drugs are becoming a larger part of the prescription drug market. In combination with -traditional indications for prescribing these drugs, new effective therapies are proving worthwhile as well. Here, a successful method for detecting both first- and second-generation antipsychotics is presented using a solid phase extraction method and LC-MS/MS detection. This method is used for many sample matrices and can also be used for detecting antidepressants, which are often prescribed in conjunction with antipsychotics.
authors: Montgomery County Coroner's Office, Dayton, OH, USA. kielye@mcohio.org
authors: Elizabeth R
authors: ER
authors: Kiely
authors: Heather M
authors: HM
authors: Antonides
mesh_terms: D014150:Antipsychotic Agents / Q000097:blood* / Q000652:urine*; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D052616:Solid Phase Extraction; D053719:Tandem Mass Spectrometry
chemical_list: D014150:Antipsychotic Agents