title: Asymptomatic bacteriuria among the elderly residents of long-term care facilities in Taiwan.
abstract: BACKGROUND
  asymptomatic bacteriuria (ASB) is common among the institutionalised elderly (IE). The cytokine levels and factors associated with ASB are unknown.
  
  
  OBJECTIVE
  to analyse cytokines and factors associated with ASB among the IE living in long-term care facilities (LTCFs) in Taiwan.
  
  
  METHODS
  this case-control study included residents ≥65 years in two LTCFs. The demographics, functional status, serum and urine levels of cytokines and proteins were compared between IE with ASB and those with sterile urine. Logistic regression was used to determine the factors associated with ASB.
  
  
  RESULTS
  the IE with ASB had elevated IL-8 in blood and urine compared with the IE with sterile urine. The Barthel index score, serum creatinine, blood IL-8 and tumour necrosis factor-α levels were significant factors associated with ASB among the IE [odds ratio (OR) 0.957, 95% CI: 0.936-0.979, P < 0.0001; OR: 0.264, 95% CI: 0.076-0.912, P = 0.035 and OR: 1.088, 95% CI: 1.022-1.158, P = 0.009; OR: 0.828, 95% CI: 0.711-0.965, P = 0.016, respectively).
  
  
  CONCLUSIONS
  functional status, renal function and blood cytokine levels were factors significantly associated with ASB among the IE living in Taiwan.
authors: Division of Family Medicine, Taipei Hospital, Department of Health, No.127, Su-Yuan Road, Hsin-Chuang District, New Taipei City, 24213 Taiwan (ROC).
authors: Hsiao-Ting
authors: HT
authors: Chang
authors: Shiow-Jen
authors: SJ
authors: Juang
authors: Yao-Jen
authors: YJ
authors: Liang
authors: Ming-Hwai
authors: MH
authors: Lin
authors: Mei-Man
authors: MM
authors: Ho
authors: Chun-Ku
authors: CK
authors: Chen
authors: Shinn-Jang
authors: SJ
authors: Hwang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D058070:Asymptomatic Diseases / Q000453:epidemiology*; D001437:Bacteriuria / Q000453:epidemiology* / Q000378:metabolism*; D002097:C-Reactive Protein / Q000378:metabolism; D016022:Case-Control Studies; D003404:Creatinine / Q000097:blood; D016207:Cytokines / Q000378:metabolism; D005260:Female; D006304:Health Status; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008134:Long-Term Care / Q000706:statistics & numerical data*; D008297:Male; D009752:Nutritional Status; D012866:Skilled Nursing Facilities / Q000706:statistics & numerical data*; D013624:Taiwan / Q000453:epidemiology
chemical_list: D016207:Cytokines; D002097:C-Reactive Protein; D003404:Creatinine