title: Endoscopic management of post operative bile duct injuries.
abstract: OBJECTIVE
  To evaluate the pattern of post-operative bile duct injuries and their subsequent endoscopic management.
  
  
  METHODS
  The prospective, non-randomised, cross-sectional study was conducted at the endoscopic suite of Surgical Unit-IV of the Civil Hospital, Karachi, over a period of three years. A total of 97 patients were included in the study. Post-procedure patients were followed up for resolution of symptoms and cessation of the bile leak. Patients with complete biliary cutoff or transection on Endoscopic Retrograde Cholaugio-Paucreatography (ERCP) were advised Magnetic Resonance Cholaugio-Papereatography (MRCP). Average followup of patients in our study was for 3 months. Mann Whitney U test was applied for non-parameteric data.
  
  
  RESULTS
  Out of 97 patients in the study, 82 (84.5%) presented with post-operative bile leakage and 15 (15.5%) with obstructive jaundice. The age of the study population ranged between 20-70 years with a mean age of 40.80 +/- 13.45 years. Male-to-female ratio was 1:3. ERCP findings in our study included 41 (42.26%) patients with bile leakage out of which 27 (27.8%) had high-grade leak and 5 (5.1%) had low-grade leak, while 9 (9.3%) patients had Common Bile Duct (CBD) stones. Among the patients, 39 (40.2%) had complete cutoff of CBD. There were 15 patients with strictures and 6 with normal ERCP. As for the bile leads, 36/41 (87.8%) patients were managed successfully by endoscopic stenting, stone removal or simple sphincterotomy. Of the 41 patients, 5 (12.2%) with bile leak developed biliary stricture on subsequent ERCP. Nine of the 15 patients (60%) with complete cutoff on initial endoscopy were successfully stented on subsequent ERCP after demonstration of biliary continuity on MRCP. Six (40%) patients were referred for surgery.
  
  
  CONCLUSIONS
  Patients with postoperative biliary leaks fare much better than those with complete cutoff or strictures. MRCP should be done in all patients where ERCP shows loss of biliary continuity. Re-exploration should be deferred till all other non-invasive modalities have been tried.
authors: Department of Surgery, Dow University of Health Sciences and Civil Hospital, Karachi.
authors: Shahriyar
authors: S
authors: Ghazanfar
authors: Sajida
authors: S
authors: Qureshi
authors: Aftab
authors: A
authors: Leghari
authors: M Ali
authors: MA
authors: Taj
authors: Saad Khalid
authors: SK
authors: Niaz
authors: M Saeed
authors: MS
authors: Quraishy
mesh_terms: D000328:Adult; D000368:Aged; D001652:Bile Ducts / Q000293:injuries* / Q000601:surgery*; D002760:Cholangiopancreatography, Endoscopic Retrograde; D049448:Cholangiopancreatography, Magnetic Resonance; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007049:Iatrogenic Disease; D008297:Male; D008875:Middle Aged; D010154:Pakistan; D011183:Postoperative Complications / Q000175:diagnosis / Q000601:surgery*; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D016896:Treatment Outcome