title: Consistency of standard laboratory strain Mycobacterium tuberculosis H 37 Rv with ethionamide susceptibility testing.
abstract: Drug susceptibility pattern of standard Mycobacterium tuberculosis strain H 37 Rv showed discrepancy in minimum inhibitory concentration method for ethionamide and consistent results were obtained for the other second line drugs namely, kanamycin and ofloxacin. It is, therefore, necessary to revisit the susceptibility testing method for ethionamide for effective clinical management of patients with drug resistant tuberculosis.
authors: Department of Bacteriology, National Institute for Research in Tuberculosis (ICMR), Chennai, India.
authors: R
authors: R
authors: Lakshmi
authors: Vanaja
authors: V
authors: Kumar
authors: Fathima
authors: F
authors: Rahman
authors: Ranjani
authors: R
authors: Ramachandran
mesh_terms: D004352:Drug Resistance, Microbial; D005000:Ethionamide / Q000494:pharmacology*; D006801:Humans; D007612:Kanamycin / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000472:pathogenicity; D015242:Ofloxacin / Q000494:pharmacology*; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D007612:Kanamycin; D015242:Ofloxacin; D005000:Ethionamide