title: [Meta-analysis of proximal femoral nail anti-rotation versus dynamic hip screw in the treatment of trochanteric fractures].
abstract: OBJECTIVE
  To compare the efficacy of proximal femoral nail anti-rotation (PFNA) versus dynamic hip screw (DHS) in the treatment of trochanteric fractures in adults.
  
  
  METHODS
  Reports of studies using randomized controlled trials (RCT) to compare PFNA with DHS in the management of intertrochanteric fractures were retrieved (up to December 5, 2011) from the Cochrane Library, MEDLINE, Elsevier, the Chinese Biomedical Database, Wanfang Data,and manually. Methodological quality of the trials was critically assessed, and relevant data were extracted. Statistical software Revman? 5.0 was used for data-analysis.
  
  
  RESULTS
  Thirteen RCTs involving 958 cases were included in the Meta-analysis. The results showed that, compared with DHS, PFNA significantly decreased the duration of surgery [WMD = -21.38, 95%CI (-33.05,-9.26), P<0.05], intra-operative blood loss [WMD = -176.36, 95%CI (-232.20, -120.52), P<0.05], the rate of post-operative complication [RR=0.46, 95%CI (0.31, 0.70), P<0.05], the rate of post-operative fixation failure[RR=0.27, 95%CI(0.11,0.62), P<0.05].
  
  
  CONCLUSIONS
  PFNA for intertrochanteric fractures is superior to DHS in regards to the mean duration of surgery, mean intra-operative blood loss, the rate of post-operative complication, and the rate of post-operative fixation failure. But there is not enough evidence to show any difference between PFNA and DHS in regards to the mean duration of hospital, the mean duration of fracture healing, the rate of post-operative fracture, the rate of post-operative coxa vara, the rate of postoperative superficial wound infection, the rate of other post-operative complications or the Harris score after surgery.
authors: Department of Orthopaedics, Xiangya Hospital, Changsha 410008, China.
authors: Chao
authors: C
authors: Zeng
authors: Yiren
authors: Y
authors: Wang
authors: Jie
authors: J
authors: Wei
authors: Shuguang
authors: S
authors: Gao
authors: Tubao
authors: T
authors: Yang
authors: Zhenqiu
authors: Z
authors: Sun
authors: Guanghua
authors: G
authors: Lei
mesh_terms: D016063:Blood Loss, Surgical / Q000706:statistics & numerical data; D001858:Bone Nails; D001863:Bone Screws; D002681:China / Q000453:epidemiology; D005593:Fracture Fixation, Internal / Q000379:methods*; D017102:Fracture Healing; D006620:Hip Fractures / Q000601:surgery*; D006801:Humans; D011183:Postoperative Complications / Q000453:epidemiology; D016032:Randomized Controlled Trials as Topic