title: Controlled synthesis and alkaline earth ion binding of switchable formamidoxime-based crown ether analogs.
abstract: The partial positive charge of amide protons is used to promote macrocyclization and form crown-ether analogs. Their deprotonation generates very selective pH-switchable alkaline earth ion receptors only in the presence of an appropriate substrate.
authors: Department of Chemistry, Queen's University, 90 Bader Lane, Kingston, ON K7L3N6, Canada.
authors: Yi
authors: Y
authors: Yan
authors: Weiwen
authors: W
authors: Zhao
authors: Ganga Viswanathan
authors: GV
authors: Bhagavathy
authors: Alexandre
authors: A
authors: Faurie
authors: Nicholas J
authors: NJ
authors: Mosey
authors: Anne
authors: A
authors: Petitjean
mesh_terms: D000577:Amides / Q000737:chemistry; D043844:Crown Ethers / Q000737:chemistry*; D003500:Cyclization; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D007477:Ions / Q000737:chemistry; D008673:Metals, Alkaline Earth / Q000737:chemistry*; D010091:Oximes / Q000737:chemistry*
chemical_list: D000577:Amides; D043844:Crown Ethers; D007477:Ions; D008673:Metals, Alkaline Earth; D010091:Oximes; C001250:formamidoxime