title: Characterization of extended-spectrum beta-lactamases, antimicrobial resistance genes, and plasmid content in Escherichia coli isolates from different sources in Rio de Janeiro, Brazil.
abstract: We analyse the diversity of extended-spectrum beta-lactamases (ESBLs), antibiotic resistance genes, and plasmid content among Escherichia coli from a community and a hospital setting in Rio de Janeiro, Brazil. ESBL producers (CTX-M-2, CTX-M-9, CTX-M-59) belonged to different phylogroups/sequence types, and bla(CTX-M) were identified in IncA/C plasmids, reinforcing the possible intraplasmid evolution of bla(CTX-M-59) from bla(CTX-M-2) and the implication of IncA/C on bla(CTX-M) spread.
authors: Departamento de Microbiologia, Imunologia e Parasitologia, Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, 20551-030 Rio de Janeiro, Brazil.
authors: Mara L P
authors: ML
authors: Queiroz
authors: Patrícia
authors: P
authors: Antunes
authors: Joana
authors: J
authors: Mourão
authors: Vânia L C
authors: VL
authors: Merquior
authors: Elisabete
authors: E
authors: Machado
authors: Luísa Vieira
authors: LV
authors: Peixe
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001938:Brazil; D016000:Cluster Analysis; D017714:Community-Acquired Infections / Q000382:microbiology; D003428:Cross Infection / Q000382:microbiology; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology / Q000235:genetics / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000382:microbiology*; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D008826:Microbial Sensitivity Tests; D058889:Molecular Typing; D010641:Phenotype; D010802:Phylogeny; D010957:Plasmids / Q000032:analysis*; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases