title: Ecology of hantaviruses in Mexico: genetic identification of rodent host species and spillover infection.
abstract: In our recent epidemiological survey conducted in Mexico for hantavirus infection, we identified three distinct viruses circulating in Mexican wild rodents, namely Montano virus (MTNV), Huitzilac virus (HUIV), and Carrizal virus (CARV). To gain a detailed understanding of hantavirus epidemiology and its associated hosts, 410 rodents were captured at eight collecting points in Morelos and Guerrero, Mexico, and examined for hantavirus seroprevalence, the presence of viral RNA, and rodent host species identification using cytochrome b gene sequences. Of the 32 species captured, seven species were positive for hantavirus: Peromyscus beatae (31/127; 24.4%), Reithrodontomys sumichrasti (6/15; 40%), Reithrodontomys megalotis (2/25; 8%), Peromyscus aztecus evides (1/1; 100%), Peromyscus megalops (1/41; 2.4%), Megadontomys thomasi (1/9; 11.1%), and Neotoma picta (1/6; 16.7%), with an overall prevalence of 10.5%; virus genome persisted in the majority of seropositive rodents. Nucleotide sequence and phylogenetic analysis showed that the viruses belonged mainly to the three lineages previously identified. The data showed that MTNV and CARV were primarily carried by P. beatae and R. sumichrasti, respectively. In addition, the data revealed an apparent complex interaction between hantaviruses and their hosts, suggesting active transmission and/or spillover infections within sympatric rodent species.
authors: Graduate School of Veterinary Medicine, Hokkaido University, Kita-18 Nish-9, Kita-Ku, Sapporo 060-0818, Hokkaido, Japan.
authors: Ngonda
authors: N
authors: Saasa
authors: Cornelio
authors: C
authors: Sánchez-Hernández
authors: María
authors: M
authors: de Lourdes Romero-Almaraz
authors: Ezequiel
authors: E
authors: Guerrero-Ibarra
authors: Alberto
authors: A
authors: Almazán-Catalán
authors: Haruka
authors: H
authors: Yoshida
authors: Daisuke
authors: D
authors: Miyashita
authors: Mariko
authors: M
authors: Ishizuka
authors: Takahiro
authors: T
authors: Sanada
authors: Takahiro
authors: T
authors: Seto
authors: Kentaro
authors: K
authors: Yoshii
authors: Celso
authors: C
authors: Ramos
authors: Kumiko
authors: K
authors: Yoshimatsu
authors: Jiro
authors: J
authors: Arikawa
authors: Ikuo
authors: I
authors: Takashima
authors: Hiroaki
authors: H
authors: Kariwa
mesh_terms: D000818:Animals; D001483:Base Sequence; D005260:Female; D006476:Orthohantavirus / Q000737:chemistry / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D018778:Hantavirus Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D006801:Humans; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D012376:Rodent Diseases / Q000453:epidemiology / Q000635:transmission / Q000821:virology*; D012377:Rodentia / Q000145:classification / Q000821:virology*; D012689:Sequence Homology, Nucleic Acid; D014764:Viral Proteins / Q000737:chemistry / Q000235:genetics
chemical_list: D014764:Viral Proteins