title: [Clinical and CT-scan presentations in tuberous sclerosis complex: report of eight pediatric cases revealed by epilepsy].
abstract: OBJECTIVE
  To describe the clinical and CT-scan features of the Tuberous sclerosis complex (TSC) revealed in children by epilepsy.
  
  
  METHODS
  It was a cross sectional descriptive study carried out in the Yaounde Gyneco-Obstetric and Pediatric Hospital (YGOPH). Eight consecutive patients consulting for epilepsy between January 2005 and December 20010 with clinical and CT-scan diagnosis criteria of TSC were included in this study.
  
  
  RESULTS
  There were two girls and six boys (aged 25months to 14years) with drug-resistant epilepsy and characteristics skin lesions of TSC (hypomelanotic macules, angiofibroma of Pringle, shagreen patches). The delay between the onset of epileptic crisis and the diagnosis of TSC varied from 10 months to 6years. One case of renal involvement and another of ophthalmic involvement were found. Cerebral CT-scan was abnormal for each patient with calcified sub-ependymal nodules in 100%, cortical tubers in 5 patients (62.5%) and one suspicion of giant sub-ependymal atrocytoma.
  
  
  CONCLUSIONS
  Features of TSC are ruled by epilepsy, skin lesions, calcified sub-ependymal nodules and cortical tubers. Thus children presenting with epilepsy, should have a careful dermatological examination to search for TSC lesions. Cerebral CT-scan will afterwards seek for characteristic brain lesions.
authors: Service de radiologie, Hopital Gyneco-obstetrique et pediatrique de Yaounde, Cameroun. bmoifo@yahoo.fr
authors: B
authors: B
authors: Moifo
authors: S
authors: S
authors: Nguefack
authors: M
authors: M
authors: Neossi Guena
authors: E
authors: E
authors: Mah
authors: E
authors: E
authors: Guegang Goudjou
authors: E
authors: E
authors: Mbonda
authors: J
authors: J
authors: Gonsu Fotsing
mesh_terms: D000293:Adolescent; D001254:Astrocytoma / Q000000981:diagnostic imaging / Q000209:etiology; D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004828:Epilepsies, Partial / Q000209:etiology*; D005260:Female; D006801:Humans; D017496:Hypopigmentation / Q000209:etiology; D008297:Male; D012867:Skin / Q000473:pathology; D015173:Supratentorial Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology; D014057:Tomography, X-Ray Computed; D014402:Tuberous Sclerosis / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging*