title: Association between Tp-e/QT ratio and prognosis in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction.
abstract: BACKGROUND
  Both the Tpeak-Tend interval (Tp-e) and the Tp-e/QT ratio have been linked to increased risk for arrhythmia. Patient Tp-e/QT ratios were investigated prior to primary percutaneous coronary intervention (pPCI) in patients with ST-segment elevation myocardial infarction (STEMI).
  
  
  OBJECTIVE
  Tp-e/QT ratio maybe associated with the prognosis in patients with ST-segment elevation.
  
  
  METHODS
  A total of 338 patients (N = 338) with STEMI treated by pPCI were included. The Tp-e and Tp-e/QT ratio were determined using electrocardiograms in the subjects exhibiting ST-segment elevation.
  
  
  RESULTS
  The Tp-e/QT ratio was correlated with both short- and long-term outcomes. Analysis of the receiver operating characteristic curve demonstrated that the optimal cutoff value for outcome prediction was a Tp-e/QT ratio of 0.29. Of the 388 patients enrolled, 115 (34.0%) exhibited a Tp-e/QT ratio ≥ 0.29. Patients with a Tp-e/QT ratio ≥ 0.29 showed elevated rates of both in-hospital death (21.9% vs 2.3%; P < 0.001) and main adverse cardiac events (MACE) (48.1% vs 15.3%; P < 0.005). After discharge, Tp-e/QT ratios ≥ 0.29 remained an independent predictor of all-cause death (35.5% vs 5.2%, P < 0.001) and cardiac death (32.3% vs 2.6%, P < 0.001).
  
  
  CONCLUSIONS
  The Tp-e/QT ratio may serve as a prognostic predictor of adverse outcomes after successful pPCI treatment in STEMI patients.
authors: Department of Emergency, Henan Provincial People's Hospital, The People's Hospital of Zhengzhou University, Zhengzhou, China.
authors: Xiangmei
authors: X
authors: Zhao
authors: Zhouliang
authors: Z
authors: Xie
authors: Yingjie
authors: Y
authors: Chu
authors: Lei
authors: L
authors: Yang
authors: Wenkai
authors: W
authors: Xu
authors: Xianzhi
authors: X
authors: Yang
authors: Xiaoyu
authors: X
authors: Liu
authors: Lixiao
authors: L
authors: Tian
mesh_terms: D000328:Adult; D000368:Aged; D002423:Cause of Death; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects / Q000379:methods; D011379:Prognosis; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome