title: Cheilitis granulomatosa (Miescher granulomatous macrocheilitis) with trisomy 21.
abstract: A 30-year-old male with Down syndrome presented to us with diffuse swelling of the lower lip of seven years duration. On examination, there was gross enlargement of his lower-lip with fissuring at places. A histopathological specimen from the lower lip showed non-caseating granulomas. We treated our patient with intralesional triamcinolone acetonide and oral clofazimine. We report this case because of the rare association of cheilitis granulomatosa with Down syndrome.
authors: Topiwala National Medical College and BYL Nair Hospital Mumbai, Maharashtra, India.
authors: Bhushan Sevakram
authors: BS
authors: Madke
authors: Deepti
authors: D
authors: Ghia
authors: Reshma
authors: R
authors: Gadkari
authors: Chitra
authors: C
authors: Nayak
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002991:Clofazimine / Q000627:therapeutic use; D004314:Down Syndrome / Q000150:complications*; D006801:Humans; D008297:Male; D008556:Melkersson-Rosenthal Syndrome / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*; D014222:Triamcinolone Acetonide / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D002991:Clofazimine; D014222:Triamcinolone Acetonide