title: Multisystem Sarcoidosis in a Patient on Interferon-α Therapy for Chronic Hepatitis C.
abstract: Sarcoidosis is a chronic multisystemic granulomatous disease that is triggered by an autoimmune process. Nowadays, this pathology represents a well-recognized but uncommon complication for antiviral treatment in hepatitis C virus (HCV) infection. Herein, we report a remarkable case of 47-year-old woman treated for chronic HCV infection; the patient has developed interferon alfa-induced sarcoidosis involving the central nervous system. The evolution was fatal despite disrupting the antiviral therapy and initiating a high-dose corticotherapy. This complication of interferon alfa treatment was reported in the literature in only one case. Through this case and a review of the literature, we aim to underline the importance of screening for sarcoidosis before and during the follow-up of HCV patients undergoing antiviral therapy.
authors: Department of Hepatogastroenterology, University Hospital of Fez, Morocco.
authors: Bouchra
authors: B
authors: Oudghiri
authors: Mohammed
authors: M
authors: Benzagmout
authors: Saïd
authors: S
authors: Boujraf
authors: Fawzi
authors: F
authors: Belahcen
authors: Adil
authors: A
authors: Ibrahimi