title: Oral intravascular fasciitis: a rare maxillofacial lesion.
abstract: Nodular fasciitis is a benign non-neoplastic myofibroblastic proliferation, involving the head in 7% to 20% of cases. Intravascular fasciitis (IVF) is a rare variant, with a unique intravascular growth pattern. Only 4 maxillofacial cases have been previously reported. We describe a 58-year-old woman with a rapidly growing, hard, mobile buccal submucosal swelling. CT scans identified a well-defined, 1.7-cm isodense lesion, located between the mental foramen and masseter muscle, which was excised under general anesthesia. A well-defined cellular nodular mass was composed of bland spindle cells, in a densely vascularized, focally myxoid matrix, involving an arterial lumen, and extending into adjacent tissues. Mitoses were rare. Immunohistochemistry was positive for smooth muscle actin, negative for keratins, S-100, epithelial membrane antigen, caldesmon, p53 and Alk. CD31 and CD34 were positive only in the vascular component, supporting the diagnosis of intravascular fasciitis.
authors: Oral and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel.
authors: Vadim
authors: V
authors: Reiser
authors: Michael
authors: M
authors: Alterman
authors: Benjamin
authors: B
authors: Shlomi
authors: Josephine
authors: J
authors: Issakov
authors: Yaniv
authors: Y
authors: Dagan
authors: Shlomi
authors: S
authors: Kleinman
authors: Amir
authors: A
authors: Shuster
authors: Ilana
authors: I
authors: Kaplan
mesh_terms: D001158:Arteries / Q000473:pathology; D003937:Diagnosis, Differential; D005146:Facial Asymmetry / Q000209:etiology; D005208:Fasciitis / Q000150:complications / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D009059:Mouth Diseases / Q000150:complications / Q000473:pathology* / Q000601:surgery; D012509:Sarcoma / Q000175:diagnosis