title: Therapeutic plasmapheresis using membrane plasma separation.
abstract: The authors present their experience with therapeutic plasmapheresis (TPE) using membrane filters at the pediatric dialysis unit of a referral center. Between January 2006 and December 2010, 486 sessions of TPE were performed in 39 patients (range 6-17 y), chiefly for atypical hemolytic uremic syndrome (HUS, n = 22), crescentic glomerulonephritis (n = 8) and focal segmental glomerulosclerosis (n = 5). Satisfactory response was noted in 32 patients, particularly with HUS (n = 22) or crescentic glomerulonephritis (n = 6). Adverse effects included chills or urticaria (n = 8 sessions), hypocalcemia (n = 6) and hypotension (n = 5). The present findings highlight the safety, efficacy and feasibility of TPE using membrane filtration.
authors: Division of Nephrology, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
authors: Aditi
authors: A
authors: Sinha
authors: Anand Narain
authors: AN
authors: Tiwari
authors: Rahul
authors: R
authors: Chanchlani
authors: V
authors: V
authors: Seetharamanjaneyulu
authors: Pankaj
authors: P
authors: Hari
authors: Arvind
authors: A
authors: Bagga
mesh_terms: D000293:Adolescent; D065766:Atypical Hemolytic Uremic Syndrome; D002648:Child; D020278:Demyelinating Autoimmune Diseases, CNS / Q000628:therapy; D005240:Feasibility Studies; D005260:Female; D005921:Glomerulonephritis / Q000628:therapy*; D005923:Glomerulosclerosis, Focal Segmental / Q000628:therapy; D020275:Guillain-Barre Syndrome / Q000628:therapy; D006463:Hemolytic-Uremic Syndrome / Q000628:therapy*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000628:therapy; D008297:Male; D010956:Plasmapheresis / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D016896:Treatment Outcome