title: Recurrent Kikuchi-Fujimoto disease.
abstract: We report the case of a 27-year-old, UK-born, Asian woman who suffered a rare recurrence of Kikuchi-Fujimoto disease. She presented with tender lymphadenopathy of the neck, fever and a prodrome of flu-like symptoms. She had a past medical history of biopsy-proven Kikuchi-Fujimoto disease of her right axilla 2 years earlier, which required no treatment. Following her repeat admission, a cervical lymph node biopsy confirmed a diagnosis of recurrent Kikuchi-Fujimoto disease. She did not improve despite treatment with paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs). She was started on high-dose prednisolone and her symptoms, pyrexia, and inflammatory markers settled within 24 h. She continually improved and the prednisolone was slowly reduced over 9 months. Kikuchi-Fujimoto is a rare, benign, self-limiting disease that presents with lymphadenopathy and fever. It rarely reoccurs. The severity, recurrence and the different body site make this an unusual case.
authors: City Hospital, Birmingham, UK. bspooner@doctors.org.uk
authors: Brendan Boyd
authors: BB
authors: Spooner
authors: Imdadur
authors: I
authors: Rahman
authors: Nigel
authors: N
authors: Langford
authors: Robin E
authors: RE
authors: Ferner
mesh_terms: D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D020042:Histiocytic Necrotizing Lymphadenitis / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D011239:Prednisolone / Q000627:therapeutic use*; D012008:Recurrence
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone