title: Isolation, biological activity, synthesis, and medicinal chemistry of the pederin/mycalamide family of natural products.
abstract: This review highlights the broad range of science that has arisen from the isolation of pederin, the mycalamides, theopederins, and onnamides, and psymberin. Specific topics include structure determination, biological activity, synthesis, and analog preparation and analysis.
authors: Department of Chemistry, University of Pittsburgh, Pennsylvania 15260, USA.
authors: R Adam
authors: RA
authors: Mosey
authors: Paul E
authors: PE
authors: Floreancig
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D001688:Biological Products; D002626:Chemistry, Pharmaceutical; D001517:Coleoptera; D003374:Coumarins; D004354:Drug Screening Assays, Antitumor; D007941:Leukemia P388; D015394:Molecular Structure; D011161:Porifera; D011714:Pyrans / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D011753:Pyrones; D013329:Structure-Activity Relationship
chemical_list: D000970:Antineoplastic Agents; D001688:Biological Products; D003374:Coumarins; D011714:Pyrans; D011753:Pyrones; C498383:psymberin; C059646:mycalamide A; C100127:pederin