title: Spectral-domain optical coherence tomography detects optic atrophy due to optic tract syndrome.
abstract: BACKGROUND
  Unilateral injury of the optic tract leads to asymmetrical optic atrophy in both eyes derived from the crossing of the nerve fibers at the chiasm. This report demonstrates unique imaging appearances of optic atrophy due to this uncommon condition detected by spectral-domain optical coherence tomography (SD-OCT).
  
  
  METHODS
  Cirrus and RTVue measurements were performed in four cases of optic tract syndrome. Circumpapillary retinal nerve fiber layer (cpRNFL) thickness was obtained from both instruments and ganglion cell complex (GCC) integrity was obtained from RTVue. The presumable reduction rates of quadrant cpRNFL thickness were calculated from the published normative database and compared between eyes with temporal hemianopia and those with nasal hemianopia.
  
  
  RESULTS
  Both devices showed significant reduction of cpRNFL thickness, but did not have statistical difference in the reduction rates at temporal or nasal quadrant cpRNFL between contralateral and ipsilateral eyes to the lesion. Color-coded maps helped to visualize the unique pattern of cpRNFL and GCC thinning.
  
  
  CONCLUSIONS
  SD-OCT can be used as a diagnostic tool for the optic tract syndrome.
authors: Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe, Japan. kanaaki@med.kobe-u.ac.jp
authors: Akiyasu
authors: A
authors: Kanamori
authors: Makoto
authors: M
authors: Nakamura
authors: Yuko
authors: Y
authors: Yamada
authors: Akira
authors: A
authors: Negi
mesh_terms: D000328:Adult; D005260:Female; D006423:Hemianopsia / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D009412:Nerve Fibers / Q000473:pathology*; D009896:Optic Atrophy / Q000175:diagnosis* / Q000209:etiology; D011681:Pupil Disorders / Q000175:diagnosis* / Q000209:etiology; D012165:Retinal Ganglion Cells / Q000473:pathology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity; D058609:Visual Field Tests; D014794:Visual Fields; D014795:Visual Pathways / Q000473:pathology*; D055815:Young Adult