title: [Current problems in the combined therapy of lung cancer].
abstract: The paper describes the general experience of modern lung cancer treatment methods application. Neoadjuvant therapy was shown to improve the long-term results of stage III patients increasing the 5-year overall survival by 7,8% (p=0,012). The special diagnostic algorithm for treatment results evaluation including autofluorescence spectrometry with 97,1% sensitivity and 88,3% specificity was developed. The adjuvant external-beam radiotherapy in patients with mediastinal lymph nodes metastases was shown to increase the 5-year overall survival (14,7% versus 19,7%) (p=0,01). The combination of endotracheobronchial surgery with chemoradiotherapy allowed to increase the median survival time of patients with inoperable lung cancer to 17 months. Isolated lung chemoperfusion was shown to increase the overall (p=0,019) and relapse-free (p=0,005) survival in patients with lung metastases.
authors: A S
authors: AS
authors: Barchuk
authors: E V
authors: EV
authors: Levchenko
authors: A I
authors: AI
authors: Arsen'ev
authors: R I
authors: RI
authors: Vagner
authors: M L
authors: ML
authors: Gel'fond
authors: A A
authors: AA
authors: Barchuk
authors: V G
authors: VG
authors: Lemekhov
authors: S V
authors: SV
authors: Kanaev
authors: S M
authors: SM
authors: Ergnian
authors: K É
authors: KÉ
authors: Gagua
authors: E S
authors: ES
authors: Timofeeva
authors: D S
authors: DS
authors: Beĭnusov
authors: S A
authors: SA
authors: Tarkov
authors: O Iu
authors: OIu
authors: Mamontov
authors: N E
authors: NE
authors: Levchenko
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000628:therapy; D059248:Chemoradiotherapy; D010478:Chemotherapy, Cancer, Regional Perfusion; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D008207:Lymphatic Metastasis; D020360:Neoadjuvant Therapy / Q000379:methods; D009367:Neoplasm Staging; D012680:Sensitivity and Specificity; D013050:Spectrometry, Fluorescence; D016019:Survival Analysis; D016896:Treatment Outcome