title: [Study of two cases of virological failure antiretrovirals in the Institute of Social Hygiene (ISH) of Dakar].
abstract: BACKGROUND
  The long term treatment of VIH/SIDA puts down majors risks among which the happening of virological failure or resistance to the anti-retroviral treatment at the patient.
  
  
  OBJECTIVE
  To study the cases of resistance to antiretroviral to a cohort of 70 patients of the social hygiene of Dakar.
  
  
  METHODS
  This is a retrospective study of the medical records of 70 patients followed in the social hygiene of Dakar during 24 mouths. Data were gathered with the help of form having following variables: The period of meadow inclusion; The period of inclusion; The period of rebound virological; The rate of CD4 count; The viral load and weight of patients.
  
  
  RESULTS
  Average of age in inclusion is of 47.5 years with a sex ratio of the women HIV 1 was dominant. Two cases of virological failure were found or (2.8%). The patient 1 was the stade II of the classification of the with as therapeutic class 2INTI + 2 INNTI. It was in stage asymptomatic with as therapeutic protocol DDI + 3TC + NVP. The patient 2 was at the stade III of the whom that is to say at the stade in AIDS with as therapeutic class: 2INTI + 1IP with the protocol of treatment DDI + 3TC +IND.
  
  
  CONCLUSIONS
  The virological failure to the newly infected persons noticed more and more in the world poses a problem of public health because it constitutes a threat for the success of the programs of treatment of the HIV/AIDS.
authors: Institut d’Hygiene Sociale de Dakar, Dakar/Fann, Senegal. pgallo92000@yahoo.fr
authors: P G
authors: PG
authors: Sow
authors: I P
authors: IP
authors: Ndiaye
authors: M
authors: M
authors: Soumare
authors: A M
authors: AM
authors: Dieye
authors: I
authors: I
authors: Traore
authors: F B
authors: FB
authors: Diallo
mesh_terms: D000328:Adult; D000368:Aged; D044966:Anti-Retroviral Agents / Q000009:adverse effects*; D018791:CD4 Lymphocyte Count; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012675:Senegal; D017211:Treatment Failure
chemical_list: D044966:Anti-Retroviral Agents