title: Adaxial-abaxial patterning: a novel function of the GABA shunt.
abstract: Adaxial-abaxial patterning in lateral organ development is important for proper tissue differentiation and the entire shape of the organs. Although many transcriptional regulators are known to be involved in adaxial-abaxial patterning, the molecular mechanisms of the initial step of adaxial-abaxial polarity formation are still unclear. To determine these mechanisms, we have been analyzing the abaxial-specific expression of FILAMENTOUS FLOWER (FIL), which encodes a putative transcription factor. Recently, we found that the enf1 mutant, which has a mutation in the succinicsemialdehyde (SSA)-degrading enzyme, reduces the robustness of FIL expression patterning and has abnormally shaped leaves. ( 1)  Here, we show that the transcriptomic data of enf1 provide more information on the relationship between SSA and adaxial-abaxial patterning, and we discuss the novel metabolic pathways of SSA production and the potential that the enf1 mutant represents a new tool in research on adaxial-abaxial polarity formation.
authors: Laboratory of Plant Organ Development, National Institute for Basic Biology, Myodaiji, Okazaki, Japan.
authors: Koichi
authors: K
authors: Toyokura
authors: Makoto
authors: M
authors: Hayashi
authors: Mikio
authors: M
authors: Nishimura
authors: Kiyotaka
authors: K
authors: Okada
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism; D001692:Biological Transport; D019521:Body Patterning / Q000235:genetics; D018548:Cotyledon / Q000378:metabolism; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant; D017343:Genes, Plant / Q000235:genetics; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; D005680:gamma-Aminobutyric Acid