title: Clostridium difficile infection in a patient with Crohn disease.
abstract: Crohn disease is a chronic inflammatory disorder, which is rare in pediatric patients. The definite etiology and mechanism to induce an acute exacerbation of Crohn disease remains mostly unknown. The authors report on a 14-year-old girl with Crohn disease who has acute gastrointestinal symptoms caused by toxin A-producing Clostridium difficile, which mimicked a flare-up of Crohn disease. There was no preceding antibiotic prescription before the episode. The disease activity did not improve after steroid treatment, which is unusual for Crohn disease. However, all symptoms were dramatically relieved after eradication of C difficile, and led to a symptom-free period for more than 3 years. This case report aims to address the unusual presentation of a usual pathogen, C difficile, in a pediatric patient with Crohn disease.
authors: Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
authors: Chien-Hui
authors: CH
authors: Hsu
authors: Yung-Ming
authors: YM
authors: Jeng
authors: Yen-Hsuan
authors: YH
authors: Ni
mesh_terms: D000293:Adolescent; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000150:complications / Q000175:diagnosis*; D003424:Crohn Disease / Q000150:complications*; D018450:Disease Progression; D005260:Female; D006801:Humans