title: Microbial transformation of azaarenes and potential uses in pharmaceutical synthesis.
abstract: Pyridine, quinoline, acridine, indole, carbazole, and other heterocyclic nitrogen-containing compounds (azaarenes) can be transformed by cultures of bacteria and fungi to produce a variety of new derivatives, many of which have biological activity. In many cases, the microbial biotransformation processes are regio- and stereoselective so that the transformation products may be useful for the synthesis of new candidate drugs.
authors: First Moscow State Medical University of I.M. Sechenov, Moscow, Russia.
authors: Igor A
authors: IA
authors: Parshikov
authors: Alexander I
authors: AI
authors: Netrusov
authors: John B
authors: JB
authors: Sutherland
mesh_terms: D001372:Aza Compounds / Q000378:metabolism*; D001419:Bacteria / Q000378:metabolism*; D001711:Biotransformation; D005658:Fungi / Q000378:metabolism*; D004364:Pharmaceutical Preparations
chemical_list: D001372:Aza Compounds; D004364:Pharmaceutical Preparations