title: Active retinitis in an infant with postnatally acquired cytomegalovirus infection.
abstract: Congenital cytomegalovirus (CMV) is frequently associated with active retinitis. In contrast, in the immunocompetent neonate with postnatally acquired CMV infection retinitis is rarely present and usually does not progress. We describe the case of an infant with postnatal CMV infection and active retinitis diagnosed at 20 days of life. Owing to the rapid progression of the retinitis, therapy with intravenous ganciclovir was performed, with prompt regression of the retinitis. Therapy was then continued with oral valganciclovir for one further week. Although very unusual, CMV retinitis has to be taken into consideration in neonates with early postnatally acquired CMV infection, as an early diagnosis and treatment may be crucial to avoid visual impairment.
authors: Department of Neonatology, Bambino Gesù Children's Hospital, Rome, Italy. piersigilli@opbg.net
authors: F
authors: F
authors: Piersigilli
authors: G
authors: G
authors: Catena
authors: M R
authors: MR
authors: De Gasperis
authors: S
authors: S
authors: Lozzi
authors: C
authors: C
authors: Auriti
mesh_terms: D000998:Antiviral Agents / Q000008:administration & dosage; D017726:Cytomegalovirus Retinitis / Q000175:diagnosis* / Q000188:drug therapy; D015774:Ganciclovir / Q000008:administration & dosage; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male
chemical_list: D000998:Antiviral Agents; D015774:Ganciclovir