title: Electrocatalysis for the oxidation of NADH based on beta-cyclodextrin/multi-walled carbon nanotubes modified ITO electrode.
abstract: In this study, the new nanocomposites of beta-cyclodextrin (beta-CD) and multi-walled carbon nanotubes (MWNTs) have been prepared and deposited on the indium tin oxide (ITO) electrodes to form the beta-CD/MWNTs modified ITO electrodes. These novel modified electrodes exhibited the abilities to lower the electrooxidation potentials of NADH substantially (ca. 600 mV) in comparison with bare ITO electrodes. Furthermore, a linear response to NADH in the concentration range of 4.0 x 10(-6) to 3.2 x 10(-3) mol/L was observed, with a detection limit of 8.0 x 10(-7) mol/L. Such ability of the novel nanocomposites to promote the electron-transfer reaction of NADH suggests great promise for dehydrogenase-based amperometric biosensors.
authors: State Key Laboratory of Bioelectronics (Chien-Shiung Wu Laboratory), Southeast University, Nanjing 210096, PR China.
authors: Xiaojing
authors: X
authors: Wu
authors: Hui
authors: H
authors: Jiang
authors: Xuemei
authors: X
authors: Wang
mesh_terms: D002384:Catalysis; D055664:Electrochemical Techniques; D004566:Electrodes; D046529:Microscopy, Electron, Transmission; D009243:NAD / Q000737:chemistry*; D037742:Nanotubes, Carbon; D010084:Oxidation-Reduction; D015203:Reproducibility of Results; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D037742:Nanotubes, Carbon; D047392:beta-Cyclodextrins; D009243:NAD; C031215:betadex