title: Coronary angiographic findings and conventional coronary artery disease risk factors of Indo-Guyanese immigrants with stable angina pectoris and acute coronary syndromes.
abstract: BACKGROUND
  The prevalence of coronary artery disease (CAD) among migrant Indian populations exceeds that of Caucasians. Migrant Indians also suffer from more premature, clinically aggressive and angiographically extensive, (i.e., 3-vessel disease). It is not known whether the extent of angiographic CAD or the conventional CAD risk factors of Indo-Guyanese (IG) immigrants differs from that of Caucasians.
  
  
  METHODS
  We reviewed the conventional CAD risk factors and angiographic findings of 198 IG and 191 Caucasians who were consecutively referred for cardiac catheterization with a diagnosis of stable angina pectoris or acute coronary syndrome.
  
  
  RESULTS
  Three-vessel CAD was approximately 1.5 times more common among IG than Caucasians (34.8% vs. 24.0%; P = .02). Age (P = .01), male sex (P = .03) and diabetes mellitus (P = .05) were independently associated with an increased likelihood of 3-vessel CAD and there was a trend towards IG ethnicity predicting 3-vessel disease (P = .13). The frequency of diabetes mellitus (51.5% vs. 30.9%; P <.001), hypertension (82.3% vs. 67.0%; P < .001) and dyslipidemia (75.5% vs. 60.2%; P = .001) were significantly greater among IG, however, that of smoking was not. While IG were significantly leaner than Caucasians (27.7 kg/m2 vs. 30.0 kg/m2 ; P < .001), their mean body mass index fell within the ethnic-specific range for obesity.
  
  
  CONCLUSIONS
  We conclude that IG immigrants presenting for coronary angiography have significantly higher rates of 3-vessel CAD as well as higher rates of diabetes mellitus, hypertension and dyslipidemia than Caucasians. Aggressive screening, prevention and treatment may be warranted in this cohort.
authors: Mount Sinai School of Medicine, New York, New York, USA. jeffrey.silbiger@mssm.edu
authors: Jeffrey J
authors: JJ
authors: Silbiger
authors: Russell
authors: R
authors: Stein
authors: Biana
authors: B
authors: Trost
authors: Jonathan
authors: J
authors: Shaffer
authors: Jin-Hee
authors: JH
authors: Kim
authors: Pilar
authors: P
authors: Cohen
authors: Mazullah
authors: M
authors: Kamran
mesh_terms: D054058:Acute Coronary Syndrome / Q000000981:diagnostic imaging / Q000208:ethnology; D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000208:ethnology; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000208:ethnology*; D003920:Diabetes Mellitus / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000208:ethnology; D050171:Dyslipidemias / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000208:ethnology; D054242:Emigrants and Immigrants; D005260:Female; D006172:Guyana / Q000208:ethnology; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D009518:New York / Q000453:epidemiology; D010641:Phenotype; D015995:Prevalence; D012307:Risk Factors; D044465:White People