title: Oncogenic osteomalacia associated with mesenchymal tumor in the middle cranial fossa: a case report.
abstract: BACKGROUND
  Tumor-induced osteomalacia is a paraneoplastic syndrome of hypophosphatemia. Osteomalacia causes multiple bone fractures and severe pain.
  
  
  METHODS
  We report the case of a 57-year-old Japanese man with tumor-induced osteomalacia associated with a middle cranial fossa bone tumor. The tumor was successfully resected by using a middle fossa epidural approach. His phosphate level recovered to a normal range immediately after the surgery.
  
  
  CONCLUSIONS
  It is rare that tumor-induced osteomalacia originates from the middle skull base. This report suggests that, if patients have a clinical and biochemical picture suggestive of tumor-induced osteomalacia, it is crucial to perform a meticulous examination to detect the tumor or the lesion responsible for the tumor. The serum level of fibroblast growth factor 23 is the most reliable marker for evaluating the treatment outcome of tumor-induced osteomalacia.
authors: Department of Neurosurgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan. chokyui@med.osaka-cu.ac.jp.
authors: Isao
authors: I
authors: Chokyu
authors: Kenichi
authors: K
authors: Ishibashi
authors: Takeo
authors: T
authors: Goto
authors: Kenji
authors: K
authors: Ohata