title: Accelerated vaccine development against emerging infectious diseases.
abstract: Emerging and re-emerging infectious diseases represent a major challenge to vaccine development since it involves two seemingly contradictory requirements. Rapid and flexible vaccine generation while using technologies and processes that can facilitate accelerated regulatory review. Development in the "-omics" in combination with advances in vaccinology offer novel opportunities to meet these requirements. Here we describe how a consortium of five different organizations from academia and industry is addressing these challenges. This novel approach has the potential to become the new standard in vaccine development allowing timely deployment to avert potential pandemics.
authors: Vaccine and Immunotherapy Center, Infectious Diseases Medicine, Massachusetts General Hospital, Charlestown, MA, USA.
authors: Pierre R
authors: PR
authors: Leblanc
authors: Jianping
authors: J
authors: Yuan
authors: Tim
authors: T
authors: Brauns
authors: Jeffrey A
authors: JA
authors: Gelfand
authors: Mark C
authors: MC
authors: Poznansky
mesh_terms: D006801:Humans; D021821:Communicable Diseases, Emerging / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission; D017277:Drug Approval; D055808:Drug Discovery / Q000639:trends; D014612:Vaccines / Q000276:immunology; D000818:Animals; D051379:Mice
chemical_list: D014612:Vaccines