title: [Assessment of ropivacaine postoperative analgesic effect after periapical maxillary incisors surgery].
abstract: OBJECTIVE
  Ropivacaine is a relatively new long-acting local anesthetic. The aim of this study was to compare the postoperative analgesic effect of topical anesthetics ropivacaine 0.75% and lidocaine 2% with adrenaline in the postoperative treatment of periapical lesions in the maxilla.
  
  
  METHODS
  The study was conducted on 60 subjects, divided into two groups. The study-group received 0.75% ropivacaine without a vasoconstrictor, while the control group was treated with 2% lidocaine with adrenaline (1 : 80.000). Block anesthesia for n. infraorbitalis was used and local anesthetics were applied also on the palatine side for the end branches of n. nasopalatinus. The following parameters were observed: time elapsed from the application of an anesthetic until the first occurrence of pain after the surgery and first intake of an analgesic, the intensity of initial pain, pain intensity 6 h after the application of anesthetics and the total number of analgesics taken within 24 h after the completion of surgery.
  
  
  RESULTS
  The pain appeared statistically significantly earlier in the patients who had been given lidocaine with adrenaline (p < 0.001), while statistically significantly higher mean values of initial postoperative pain (p < 0.05) and pain intensity 6 h after the intervention (p < 0.01) were also registered in the same group of patients. In the period of 24 h upon the intervention, the study-group patients were taking less analgesics as compared to the control-group subjects (46.6% vs 73.3%), who were given analgesics earlier, although no statistically significant differences were observed related to the number of analgesic doses taken.
  
  
  CONCLUSIONS
  The results of our study indicate a better postoperative analgesic effect of ropivacaine as compared to lidocaine with adrenaline.
authors: Odeljenje oralne hirurgije, Klinika za stomatologiju, Medicinski fakultet, Univerzitet u Nisu, Nis, Srbija. tijanicm@yahoo.com
authors: Milos
authors: M
authors: Tijanić
authors: Nikola
authors: N
authors: Burić
authors: Goran
authors: G
authors: Jovanović
authors: Simona
authors: S
authors: Stojanović
authors: Milan
authors: M
authors: Spasić
mesh_terms: D000328:Adult; D000577:Amides / Q000008:administration & dosage*; D000766:Anesthesia, Dental; D000779:Anesthetics, Local / Q000008:administration & dosage*; D004837:Epinephrine / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007180:Incisor; D008012:Lidocaine / Q000008:administration & dosage; D008297:Male; D008437:Maxilla; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D010483:Periapical Diseases / Q000601:surgery*; D000077212:Ropivacaine; D014662:Vasoconstrictor Agents / Q000008:administration & dosage; D055815:Young Adult
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D014662:Vasoconstrictor Agents; D000077212:Ropivacaine; D008012:Lidocaine; D004837:Epinephrine