title: Chronic autoimmune urticaria.
abstract: Chronic urticaria is common and patients may present with transient eruption of itchy, eruthematous, edematous swellings of the dermis, which lasts more than six weeks. One type of chronic idiopathic urticaria, and part of it, is the chronic autoimmune urticaria. The chronic autoimmune urticaria is caused by high affinity of IgE receptors (anti-FcRI) and less frequently by anti-IgE autoantibodies, also the role of complement activation, that leads to mast and basophil activation. Despite many recent advances in the understanding of chronic autoimmune urticaria, this condition remains a major challenge in the terms of its etiology, investigations, and management.
authors: Department of Internal Medicine, Siloam International Hospitals. Siloam Hospitals Group's CEO Office, Siloam Hospital Lippo Village 5th floor. Jl. Siloam no. 6, Karawaci, Indonesia. wadiswas@yahoo.com
authors: Wardhana
authors: E A
authors: EA
authors: Datau
mesh_terms: D001323:Autoantibodies / Q000097:blood; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology*; D002908:Chronic Disease; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D017455:Receptors, IgE / Q000276:immunology; D015398:Signal Transduction / Q000276:immunology; D014581:Urticaria / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D006634:Histamine H1 Antagonists; D007166:Immunosuppressive Agents; D017455:Receptors, IgE; D007073:Immunoglobulin E