title: Angle-dependent resonance of localized and propagating surface plasmons in microhole arrays for enhanced biosensing.
abstract: The presence of microhole arrays in thin Au films is suited for the excitation of localized and propagating surface plasmon (SP) modes. Conditions can be established to excite a resonance between the localized and propagating SP modes, which further enhanced the local electromagnetic (EM) field. The co-excitation of localized and propagating SP modes depends on the angle of incidence (θ(exc)) and refractive index of the solution interrogated. As a consequence of the enhanced EM field, enhanced sensitivity and an improved response for binding events by about a factor of 3 to 5 was observed with SPR sensors in the Kretschmann configuration for a set of experimental conditions (λ(SPR), θ(exc), and η). Thus, microhole arrays can improve sensing applications of SPR based on classical prism-based instrumentation and are suited for SP-coupled spectroscopic techniques.
authors: Département de chimie, Université de Montréal, C.P. 6128 Succ. Centre-Ville, Montreal, QC H3C 3J7, Canada.
authors: Ludovic S
authors: LS
authors: Live
authors: Anuj
authors: A
authors: Dhawan
authors: Kirsty F
authors: KF
authors: Gibson
authors: Hugo-Pierre
authors: HP
authors: Poirier-Richard
authors: Duncan
authors: D
authors: Graham
authors: Michael
authors: M
authors: Canva
authors: Tuan
authors: T
authors: Vo-Dinh
authors: Jean-François
authors: JF
authors: Masson
mesh_terms: D055910:Antibodies, Immobilized / Q000276:immunology; D004867:Equipment Design; D006046:Gold / Q000737:chemistry; D007074:Immunoglobulin G / Q000032:analysis*; D046228:Microarray Analysis / Q000295:instrumentation*; D012031:Refractometry; D020349:Surface Plasmon Resonance / Q000295:instrumentation*
chemical_list: D055910:Antibodies, Immobilized; D007074:Immunoglobulin G; D006046:Gold