title: Patient-specific factors relating to medication adherence in a post-percutaneous coronary intervention cohort.
abstract: OBJECTIVE
  To explore the association between medication adherence and qualitatively characterised patient-specific themes relating to medication adherence in patients following percutaneous coronary intervention (PCI).
  
  
  METHODS
  Data-collection questionnaires and qualitative topic guides were piloted in two patients. A validated questionnaire generated an adherence score for a convenience sample of 20 patients within 7 days of PCI. Semi-structured qualitative interviews were subsequently carried out with all patients to explore patient-specific themes relating to measured medication adherence.
  
  
  RESULTS
  Fourteen out of 20 patients (70%) had scores indicative of good adherence. Key factors associated with good adherence included having a good relationship with the doctor, having an understanding of the condition, knowledge of the indications and consequences of non-adherence, perceived health benefits and medications eliciting tangible symptom control. There were misconceptions of concern regarding adverse drug reactions and the importance of aspirin, both of which had a negative effect on adherence. The role of the community pharmacist was sometimes, although not always, misunderstood.
  
  
  CONCLUSIONS
  This study suggests there is an association between patients' beliefs, knowledge, understanding and misconceptions about medication and their adherence in a post-PCI cohort. To optimise medication adherence it is vital for prescribers to remain patient-focused and cognisant of patient-specific themes relating to medication adherence.
authors: Highland Clinical Research Facility, Centre for Health Science, Inverness, UK. gordon.rushworth@nhs.net
authors: Gordon F
authors: GF
authors: Rushworth
authors: Scott
authors: S
authors: Cunningham
authors: Alasdair
authors: A
authors: Mort
authors: Ian
authors: I
authors: Rudd
authors: Stephen J
authors: SJ
authors: Leslie
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D001241:Aspirin / Q000627:therapeutic use; D003157:Community Pharmacy Services / Q000458:organization & administration; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D010595:Pharmacists / Q000458:organization & administration; D010817:Physician-Patient Relations; D010865:Pilot Projects; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D024382:Professional Role; D011795:Surveys and Questionnaires
chemical_list: D010975:Platelet Aggregation Inhibitors; D001241:Aspirin