title: Dual infection with Pythium insidiosum and Blastomyces dermatitidis in a dog.
abstract: A 4-year-old male neutered Labrador Retriever with severe gastrointestinal signs, but no respiratory signs, was diagnosed with multifocal pyogranulomatous gastritis, enteritis, and lymphadenitis with intralesional hyphae and multifocal pyogranulomatous pneumonia with intralesional yeast. Based on cytologic evaluation, histologic examination with special stains, and immunohistochemical analysis of tissues collected antemortem or at necropsy, dual infections with Pythium insidiosum and Blastomyces dermatitidis were detected and are reported for the first time.
authors: Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA. sconnoll@illinois.edu
authors: Sara L
authors: SL
authors: Connolly
authors: Chad
authors: C
authors: Frank
authors: Craig A
authors: CA
authors: Thompson
authors: William G
authors: WG
authors: Van Alstine
authors: Hylton
authors: H
authors: Gelb
authors: Hock Gan
authors: HG
authors: Heng
authors: Emily
authors: E
authors: Klosterman
authors: Matti
authors: M
authors: Kiupel
authors: Amy M
authors: AM
authors: Grooters
mesh_terms: D000818:Animals; D044963:Biopsy, Fine-Needle; D001758:Blastomyces / Q000302:isolation & purification*; D001759:Blastomycosis / Q000150:complications / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000382:microbiology / Q000469:parasitology / Q000473:pathology*; D004285:Dogs; D004386:Duodenum / Q000469:parasitology / Q000473:pathology; D004751:Enteritis / Q000150:complications / Q000469:parasitology / Q000473:pathology / Q000662:veterinary; D005756:Gastritis / Q000150:complications / Q000469:parasitology / Q000473:pathology / Q000662:veterinary; D025301:Hyphae; D008168:Lung / Q000382:microbiology; D008198:Lymph Nodes / Q000469:parasitology / Q000473:pathology; D008199:Lymphadenitis / Q000150:complications / Q000469:parasitology / Q000473:pathology / Q000662:veterinary; D008297:Male; D011014:Pneumonia / Q000150:complications / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D011379:Prognosis; D058968:Pythiosis / Q000150:complications / Q000469:parasitology / Q000473:pathology / Q000662:veterinary*; D011775:Pythium / Q000302:isolation & purification*; D013270:Stomach / Q000469:parasitology; D015003:Yeasts