title: Hypertension, hypercoagulability and the metabolic syndrome: a cluster of risk factors for cardiovascular disease.
abstract: Cardiovascular disease (CVD) is one of the main causes of mortality in the world representing around 30% of all deaths. It constitutes also an important factor in morbidity and incapacity. There are several related CVD risk factors such as hypertension, metabolic syndrome (MetS) and hypercoagulability. The exact mechanisms that underlie the relation between those factors and CVD are not sufficiently known yet; pathogenic explanations are lacking also for the mechanisms relating metabolic factors to insulin resistance (IR) and the association with the development of atherosclerosis and thrombosis. The possible links between hypertension, hemostasis alterations and MetS are examined in this report.
authors: INSERM, U961, Vandoeuvre-les-Nancy, Nancy, France.
authors: Xianqing
authors: X
authors: Mao
authors: Karima
authors: K
authors: Ait-Aissa
authors: Jeremy
authors: J
authors: Lagrange
authors: Gina
authors: G
authors: Youcef
authors: Huguette
authors: H
authors: Louis
mesh_terms: D000818:Animals; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000378:metabolism; D004195:Disease Models, Animal; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000378:metabolism; D024821:Metabolic Syndrome / Q000150:complications* / Q000378:metabolism; D051379:Mice; D051381:Rats; D012307:Risk Factors; D019851:Thrombophilia / Q000150:complications* / Q000378:metabolism