title: Retinopathy of prematurity in the Dominican Republic: challenges to screening and prevention.
abstract: OBJECTIVE
  To determine the incidence of retinopathy of prematurity (ROP) in an intensive care nursery in the Dominican Republic and to identify factors that impact ROP outcomes, screening, and treatment.
  
  
  METHODS
  A database analysis was performed. The database was prospectively created by the pediatric ophthalmologist in a public maternity hospital in Santo Domingo during 2009. From January to December, all infants (n = 234) who received at least one ophthalmologic examination for ROP were included. ROP screening criteria were based upon: (1) American Academy of Pediatrics guidelines and (2) the presence of critical illness in larger, more mature infants at the discretion of the neonatologist.
  
  
  RESULTS
  Overall, 22% were diagnosed with ROP and 4.3% had severe disease. Infants with ROP had a mean birth weight of 1452 g and a mean gestational age of 31 weeks, with 35% having a gestational age >32 weeks. In multivariable regression, only gestational age remained significant (0.8, 0.68 to 0.95). Twenty-two percent diagnosed with ROP did not complete all screening procedures.
  
  
  CONCLUSIONS
  There are many challenges to preventing and treating ROP in the Dominican Republic. Increased awareness of the detrimental effects of hyperoxia, broader screening criteria, and an improved screening program will help to reduce visual impairment from ROP.
authors: Department of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, Massachusetts 02111, USA. Jlee9@tuftsmedicalcenter.org
authors: Jennifer W
authors: JW
authors: Lee
authors: Francheyska
authors: F
authors: SilfaMazara
authors: Ana
authors: A
authors: Olivier
authors: Francis
authors: F
authors: McCabe
authors: Luis
authors: L
authors: Rivera
authors: Rosina Negrin
authors: RN
authors: Martin
authors: Jonathan M
authors: JM
authors: Davis
mesh_terms: D001724:Birth Weight; D004293:Dominican Republic / Q000453:epidemiology; D005260:Female; D005325:Fetal Organ Maturity; D005865:Gestational Age; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007234:Infant, Premature; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data; D015931:Intensive Care, Neonatal / Q000379:methods*; D008297:Male; D015997:Neonatal Screening / Q000379:methods / Q000458:organization & administration; D012044:Regression Analysis; D012178:Retinopathy of Prematurity / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D012307:Risk Factors; D012720:Severity of Illness Index