title: Unique topographic distribution of greyhound nonsuppurative meningoencephalitis.
abstract: Greyhound nonsuppurative meningoencephalitis is an idiopathic breed-associated fatal meningoencephalitis with lesions usually occurring within the rostral cerebrum. This disorder can only be confirmed by postmortem examination, with a diagnosis based upon the unique topography of inflammatory lesions. Our purpose was to describe the magnetic resonance (MR) imaging features of this disease. Four Greyhounds with confirmed Greyhound nonsuppurative meningoencephalitis were evaluated by MR imaging. Lesions predominantly affected the olfactory lobes and bulbs, frontal, and frontotemporal cortical gray matter, and caudate nuclei bilaterally. Fluid attenuation inversion recovery (FLAIR) and T2 weighted spin-echo (T2W) sequences were most useful to assess the nature, severity, extension, and topographic pattern of lesions. Lesions were predominantly T2-hyperintense and T1-isointense with minimal or absent contrast enhancement.
authors: School of Veterinary Medicine, University Veterinary Hospital, University College, Dublin, Ireland. eloisaterzo@yahoo.it
authors: Eloisa
authors: E
authors: Terzo
authors: J Fraser
authors: JF
authors: McConnell
authors: Robert E
authors: RE
authors: Shiel
authors: Hester
authors: H
authors: McAllister
authors: Sebastien
authors: S
authors: Behr
authors: Simon L
authors: SL
authors: Priestnall
authors: Ken C
authors: KC
authors: Smith
authors: Catherine M
authors: CM
authors: Nolan
authors: John J
authors: JJ
authors: Callanan
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology; D004283:Dog Diseases / Q000175:diagnosis*; D004285:Dogs; D005260:Female; D008279:Magnetic Resonance Imaging / Q000662:veterinary*; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis* / Q000473:pathology / Q000662:veterinary*