title: p53 and metabolism: old player in a new game.
abstract: Metabolic reprogramming is an integral part of tumorigenesis. Tumor suppressor p53 is a well studied transcription factor intimately linked with the control of cell cycle progression and apoptosis. Here, we discuss the emerging role of p53 in the transcriptional regulation of metabolism. This activity is a key component of p53 tumor suppression function.
authors: Molecular Oncology Laboratory, National Institute of Immunology Aruna Asaf Ali Marg, New Delhi, India.
authors: Nirmalya
authors: N
authors: Sen
authors: Yatendra Kumar
authors: YK
authors: Satija
authors: Sanjeev
authors: S
authors: Das
mesh_terms: D017209:Apoptosis; D002453:Cell Cycle; D002471:Cell Transformation, Neoplastic / Q000235:genetics / Q000378:metabolism*; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D014157:Transcription Factors; D016159:Tumor Suppressor Protein p53 / Q000235:genetics / Q000378:metabolism*
chemical_list: D014157:Transcription Factors; D016159:Tumor Suppressor Protein p53