title: Spontaneous distal biceps tendon ruptures: are they related to statin administration?
abstract: The purpose of this study is to identify a possible correlation between statin administration and incidence of spontaneous distal biceps tendon ruptures. We retrospectively reviewed 104 patients with distal biceps tendon rupture that were treated surgically from 2004 to 2010, 102 males and two females with mean age 47 years (range, 22-78). Patients were divided based on the mechanism of injury and statin administration. After statistical analysis, it was found nearly two times more likely to have spontaneous distal biceps tendon rupture with use of statins. Patients in Group 1 (spontaneous tendon rupture) compared to Group 2 (provoked tendon rupture) were older, had weaker postoperative strength but similar postoperative ROM. Patients taking statins compared to those that were not taking statins were older, had same postoperative strength and similar postoperative ROM. Based on the results of our study we conclude that there is a trend of association of spontaneous distal biceps tendon ruptures with statin administration.
authors: Christine M. Kleinert Institute for Hand and Microsurgery, Louisville, KY 40202, USA. csavvidou24@gmail.com
authors: Christiana
authors: C
authors: Savvidou
authors: Rodrigo
authors: R
authors: Moreno
mesh_terms: D000328:Adult; D000368:Aged; D001134:Arm Injuries / Q000139:chemically induced* / Q000601:surgery; D005260:Female; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016059:Range of Motion, Articular; D012189:Retrospective Studies; D012307:Risk Factors; D012421:Rupture / Q000139:chemically induced / Q000601:surgery; D013708:Tendon Injuries / Q000139:chemically induced* / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors