title: Frequency of complications and usefulness of the minor salivary gland biopsy.
abstract: Findings of specific antibodies and histopathology data are essential for the diagnosis of Sjögren syndrome (SS). Although the minor salivary gland biopsy (MSGB) is technically simple, it needs to be performed in a medical institution to avoid complications.
  
  
  OBJECTIVE
  To determine the frequency of complications and the usefulness of this technique.
  
  
  METHODS
  Patients who underwent a minor salivary gland biopsy for a possible diagnosis of SS at Rivadavia Hospital between October 2007 and May 2010 where included. The patients were seen a week and a month after the procedure for follow up.
  
  
  RESULTS
  Frequency of acute complications (n=186): 15 patients; 8.1%, 95% CI: 4.7-13.2 (Bleeding 7.5%, syncope 3.2%, hematoma 2.7%. No accidents occurred). Medium term complications (n=164): 16 patients: 9.75%, 95% CI: 5.9-15.6 (pain 7.32%, inflammation 3.66%, sensitivity disorders 3.05%, granuloma 1.22%,). No infections or suture dehiscence occurred. Microscopic results: 154 biopsy reports were received: glandular 90.9%, 95% CI: 85-95 (typical, sialadenitis, grade III and IV infiltration).
  
  
  CONCLUSIONS
  MSGB has very low frequency of medium term and acute complications and it has high usefulness.
authors: Servicio de Reumatología, Hospital Bernardino Rivadavia, Ciudad Autónoma de Buenos Aires, Argentina. mrseisdedos@intramed.net
authors: María
authors: M
authors: Lida Santiago
authors: María Renata
authors: MR
authors: Seisdedos
authors: Rodrigo Nicolás
authors: RN
authors: García Salinas
authors: Anastasia
authors: A
authors: Secco
authors: Lucila
authors: L
authors: Marino Claverie
authors: Lorena
authors: L
authors: Techera
authors: Lorena
authors: L
authors: Takashima
authors: Pedro
authors: P
authors: Aicardi
authors: Marco Antonio
authors: MA
authors: Sandi Rosales
authors: Elizabeth
authors: E
authors: Knobel
authors: Sebastián Juan
authors: SJ
authors: Magri
authors: Antonio Carlos
authors: AC
authors: Catalán Pellet
mesh_terms: D001323:Autoantibodies / Q000097:blood; D001706:Biopsy / Q000009:adverse effects; D005260:Female; D006470:Hemorrhage / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000453:epidemiology / Q000209:etiology; D011446:Prospective Studies; D012470:Salivary Glands, Minor / Q000473:pathology*; D012680:Sensitivity and Specificity; D012859:Sjogren's Syndrome / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D013575:Syncope / Q000453:epidemiology / Q000209:etiology
chemical_list: D001323:Autoantibodies; D007166:Immunosuppressive Agents