title: A case of Helicobacter pylori infection complicated with gastric cancer, gastric mucosa-associated lymphoid tissue lymphoma, and idiopathic thrombocytopenic purpura successfully treated with laparoscopy-assisted total gastrectomy and splenectomy.
abstract: Helicobacter pylori infection plays a key role in the pathogenesis of H. pylori-associated diseases, including gastroduodenal and non-gastroduodenal diseases. A 71-year-old man was evaluated for a positive fecal occult blood test by upper gastrointestinal endoscopy, which revealed H. pylori infection, two adenocarcinomas and two gastric mucosa-associated lymphoid tissue lymphomas. Hematological examination revealed low platelet-count, elevated platelet-associated immunoglobulin G and anti-H. pylori immunoglobulin G antibodies. We diagnosed H. pylori infection complicated by simultaneous occurrence of gastric cancer, gastric mucosa-associated lymphoid tissue lymphoma, and idiopathic thrombocytopenic purpura. These diseases were successfully treated with laparoscopy-assisted total gastrectomy and splenectomy, and there was no evidence of recurrence for about 2 years. This is the first reported case of H. pylori infection complicated by these three diseases and cured with laparoscopic surgery.
authors: Department of Surgery, Osaka Police Hospital, Osaka, Japan. fl930atsushi@hotmail.com
authors: A
authors: A
authors: Hamabe
authors: T
authors: T
authors: Omori
authors: T
authors: T
authors: Oyama
authors: H
authors: H
authors: Akamatsu
authors: K
authors: K
authors: Yoshidome
authors: M
authors: M
authors: Tori
authors: S
authors: S
authors: Ueshima
authors: M
authors: M
authors: Tsujimoto
authors: T
authors: T
authors: Nishida
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000601:surgery*; D000368:Aged; D005743:Gastrectomy; D016481:Helicobacter Infections / Q000150:complications; D016480:Helicobacter pylori; D006801:Humans; D010535:Laparoscopy; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications / Q000601:surgery*; D008297:Male; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications / Q000601:surgery*; D013156:Splenectomy; D013274:Stomach Neoplasms / Q000150:complications / Q000601:surgery*; D016896:Treatment Outcome