title: Consecutive cutaneous and visceral leishmaniasis manifestations involving a novel Leishmania species in two HIV patients in Thailand.
abstract: Leishmaniasis is an emerging disease in Thailand. Herein, we report on two human immunodeficiency virus (HIV)-infected patients with leishmaniasis who presented with overlapping manifestations between cutaneous and visceral leishmaniasis. Sequencing analysis of the internal transcribed spacer 1 (ITS1) of the ribosomal RNA gene showed that the species was identical to a new species recently described in Thailand. The detection of DNA of this Leishmania species in saliva may have important implications for transmission and epidemiological studies.
authors: Division of Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand. sarunyouchusri@hotmail.com
authors: Sarunyou
authors: S
authors: Chusri
authors: Thanaporn
authors: T
authors: Hortiwakul
authors: Khachornsakdi
authors: K
authors: Silpapojakul
authors: Padet
authors: P
authors: Siriyasatien
mesh_terms: D001483:Base Sequence; D004587:Electrophoresis, Agar Gel; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D016773:Leishmaniasis, Cutaneous / Q000150:complications* / Q000469:parasitology / Q000503:physiopathology; D007898:Leishmaniasis, Visceral / Q000150:complications* / Q000469:parasitology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012335:RNA, Ribosomal / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid; D013785:Thailand
chemical_list: D012335:RNA, Ribosomal