title: Intravenous fluorescein as a cause of immunoglobulin E-mediated anaphylactic shock.
abstract: We report a patient with severe anaphylactic shock immediately after injection of i.v. fluorescein. The patient recovered without sequela. Immunoglobulin E (IgE) mechanism was highly suggestive with significant increase in serum tryptase, positive basophil allergen threshold sensitivity (CD-sens) and histamine release tests towards fluorescein. This is, to our knowledge, the first report where CD-sens has been used to aid in diagnosing an IgE-mediated anaphylactic shock caused by fluorescein.
authors: Department of Anaesthesiology and Intensive Care, Central Hospital of Sogn og Fjordane, Førde, Norway.
authors: A
authors: A
authors: Breidablik
authors: G H
authors: GH
authors: De Pater
authors: C
authors: C
authors: Walther
authors: A
authors: A
authors: Nopp
authors: A B
authors: AB
authors: Guttormsen
mesh_terms: D000368:Aged; D000707:Anaphylaxis / Q000188:drug therapy / Q000209:etiology / Q000276:immunology*; D015703:Antigens, CD / Q000276:immunology; D001491:Basophils / Q000276:immunology; D002637:Chest Pain / Q000150:complications; D003287:Contrast Media / Q000009:adverse effects*; D004837:Epinephrine / Q000627:therapeutic use; D019793:Fluorescein / Q000009:adverse effects*; D006636:Histamine Release / Q000502:physiology; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D007442:Intubation, Intratracheal; D008297:Male; D009093:Mucus / Q000502:physiology; D012882:Skin Tests; D053802:Tryptases; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
chemical_list: D015703:Antigens, CD; D003287:Contrast Media; D014662:Vasoconstrictor Agents; D007073:Immunoglobulin E; D053802:Tryptases; D019793:Fluorescein; D004837:Epinephrine