title: [Postural orthostatic tachycardia syndrome (POTS): report of 15 cases].
abstract: BACKGROUND
  Patients with postural orthostatic tachycardia syndrome (POTS) report dizziness, lightheadedness, weakness, blurred vision, and fatigue upon standing. The diagnosis of the syndrome is made when an orthostatic intolerance and tachycardia appear in the standing position.
  
  
  OBJECTIVE
  To report 15 patients with POTS.
  
  
  METHODS
  Review of Tilt test reports in a period of 15 years. Those reports in which orthostatic postural tachycardia and symptoms compatible with POTS appeared, were selected for analysis.
  
  
  RESULTS
  We identified 15 patients (3.1% of all positive Tilt test reports) with compatible signs and symptoms. There was a lag of 8 -10 years between the onset of symptoms and the time of diagnosis. Most patients complained of orthostatic intolerance, dizziness and frequent fainting. Orthostatic tachycardia and symptoms occurred on average after 2.9 and 6.1 minutes, respectively,of staying in the standing position. These patients had a high frequency of family history of syncope orpresyncope (66% frequency) and hyper mobility syndrome (53% prevalence). Only 33% of the patients reported relief of their symptoms after being treated (most of them with fludrocortisone). Most patients that reported little or no relief, did not use medications or were treated for a short period.
  
  
  CONCLUSIONS
  POTS syndrome is uncommon but disturbs quality of life of those who suffer it. Its association with hyper mobility syndromes must be investigated.
authors: Servicio de Neurología y Unidad de Estudios Autonómicos, Hospital Militar de Santiago, Chile. pejimco@yahoo.com
authors: Pedro
authors: P
authors: Jiménez-Cohl
authors: Nicholas M
authors: NM
authors: Earle
authors: Beltrán R
authors: BR
authors: González
authors: Elfride J
authors: EJ
authors: Thieck
mesh_terms: D000293:Adolescent; D000328:Adult; D002317:Cardiovascular Agents / Q000627:therapeutic use; D016022:Case-Control Studies; D002648:Child; D005260:Female; D005438:Fludrocortisone / Q000627:therapeutic use; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D054972:Postural Orthostatic Tachycardia Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics; D012189:Retrospective Studies; D019462:Syncope, Vasovagal / Q000235:genetics; D018667:Tilt-Table Test; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D002317:Cardiovascular Agents; D005438:Fludrocortisone