title: Eruption delay in a 47 XXY male: a case report.
abstract: BACKGROUND
  The 47,XXY syndrome, or Klinefelter syndrome, though it is a rare occurrence, it is the most common sex choromosome disorder affecting male subjects. This syndrome is underdiagnosed and seldomly before puberty. In this case, diagnosis was made before birth, through chorion villus sampling.
  
  
  METHODS
  A 16 month-old Italian male with 47 XXY syndrome showed the absence of primary teeth, with a delay of about 8-10 months, whereas during the first 15 months of life the auxological development has been normal both in weight and height (about 50th percentile). We assumed that this delay may be linked with Klinefelter syndrome, as sexual chromosomes play an important role in the dental development.
authors: Department of Dental Science, Dental School, Alma Mater Studiorum, University of Bologna, Bologna, Italy. dr.dalessandro@gmail.com
authors: G
authors: G
authors: D'Alessandro
authors: L
authors: L
authors: Armuzzi
authors: G
authors: G
authors: Cocchi
authors: G
authors: G
authors: Piana
mesh_terms: D001827:Body Height; D001835:Body Weight; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007713:Klinefelter Syndrome / Q000503:physiopathology*; D008297:Male; D014078:Tooth Eruption / Q000502:physiology*; D014094:Tooth, Deciduous / Q000503:physiopathology*