title: Cardiac transplantation in Friedreich ataxia.
abstract: In this article, we describe a 14-year-old boy with a confirmed diagnosis of Friedreich ataxia who underwent cardiac transplantation for left ventricular failure secondary to dilated cardiomyopathy with restrictive physiology. His neurological status prior to transplantation reflected early signs of neurological disease, with evidence of dysarthria, weakness, mild gait impairment, and limb ataxia. We review the ethical issues considered during the process leading to the decision to offer cardiac transplantation.
authors: Division of Clinical and Metabolic Genetics, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada. grace.yoon@utoronto.ca
authors: Grace
authors: G
authors: Yoon
authors: Teesta
authors: T
authors: Soman
authors: Judith
authors: J
authors: Wilson
authors: Kristen
authors: K
authors: George
authors: Seema
authors: S
authors: Mital
authors: Anne I
authors: AI
authors: Dipchand
authors: Jane
authors: J
authors: McCabe
authors: William
authors: W
authors: Logan
authors: Paul
authors: P
authors: Kantor
mesh_terms: D005621:Friedreich Ataxia / Q000150:complications*; D006331:Heart Diseases / Q000209:etiology* / Q000601:surgery*; D016027:Heart Transplantation / Q000379:methods*; D006801:Humans