title: Regional odontodysplasia. A literature review and three case reports.
abstract: OBJECTIVE
  The purpose of this article is to report some unusual characteristics related to gender, location and  manifestations of severe Regional Odontodysplasia detected in three subjects. Regional Odontodysplasia is a rare  disturbance of dental development whose aetiology is still unknown. Anomalies involve enamel, dentin, pulp and dental  follicle causing atypical structure, colour, shape, size and eruptive disturbances of the affected teeth. Its early onset may lead  to craniofacial development disturbances.
  
  
  METHODS
  This article reports three cases with unusual characteristics  observed in male children who were assisted by a paediatric dentist. Generally the disease affects one hemiarch and it is  very rare that it crosses the midline as in one of the presented cases. Regional Odontodysplasia has been predominantly  described in the maxilla and in women, however these three cases are in boys and two of them occured in the mandible.
  
  
  CONCLUSIONS
  Regional Odontodysplasia is a rare disease, causing severe dental, growing and craniofacial development  anomalies. Treatment needs to be personalised, aiming at preservation of the affected teeth taking into account their risk to  develop severe infections. Parents should be made aware of the need for an extensive follow-up.
authors: Department of Preventive Dentistry, Paediatric Dentistry and Orthodontics, Complutense University of Madrid, Spain. barberia@odon.ucm.es
authors: E
authors: E
authors: Barbería
authors: A
authors: A
authors: Sanz Coarasa
authors: A
authors: A
authors: Hernández
authors: C
authors: C
authors: Cardoso-Silva
mesh_terms: D000293:Adolescent; D001641:Bicuspid / Q000002:abnormalities; D002648:Child; D002675:Child, Preschool; D003481:Cuspid / Q000002:abnormalities; D003782:Dental Pulp / Q000002:abnormalities; D003937:Diagnosis, Differential; D006801:Humans; D007180:Incisor / Q000002:abnormalities; D008297:Male; D008963:Molar / Q000002:abnormalities; D018126:Odontodysplasia / Q000175:diagnosis*; D011859:Radiography; D014083:Tooth Germ / Q000002:abnormalities; D014094:Tooth, Deciduous / Q000002:abnormalities; D014097:Tooth, Unerupted / Q000000981:diagnostic imaging