title: Symmetrical drug-related intertriginous and flexural exanthema secondary to topical 5-fluorouracil.
abstract: We report the case of a 56-year-old man who developed a distinctive skin eruption after treating actinic keratoses on the dorsal aspects of his right and left hands with topical 5-fluorouracil (5-FU). The distribution of his rash was characteristic of symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), also known as baboon syndrome.
authors: West Virginia University School of Medicine, Morgantown, WV 26506, USA. rpowers@hsc.wvu.edu
authors: Roxann
authors: R
authors: Powers
authors: Rachel
authors: R
authors: Gordon
authors: Kenrick
authors: K
authors: Roberts
authors: Rodney
authors: R
authors: Kovach
mesh_terms: D000279:Administration, Cutaneous; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005076:Exanthema / Q000139:chemically induced* / Q000473:pathology; D005472:Fluorouracil / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006229:Hand Dermatoses / Q000139:chemically induced / Q000473:pathology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D055623:Keratosis, Actinic / Q000188:drug therapy; D008297:Male; D008875:Middle Aged
chemical_list: D007166:Immunosuppressive Agents; D005472:Fluorouracil