title: Mucous membrane pemphigoid with antibodies against β3 subunit of laminin-332: first report from India.
abstract: Mucous membrane pemphigoid (MMP) is a chronic, recurrent, progressive, subepidermal blistering disorder, mainly affecting the mucous membranes. Anti-laminin 332 MMP is a distinct subset of MMP with antibodies, mainly targeted against α3 or γ2 subunit. Antibodies exclusively against β3 subunit are rarely seen. An internal malignancy is frequently associated with anti-laminin 332 MMP. This disorder usually responds poorly to treatment, requiring multidisciplinary approach. Herein, we describe the first case of anti-laminin-332 MMP from India, which showed antibodies exclusively to β3 subunit.
authors: Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors: Amrinder Jit
authors: AJ
authors: Kanwar
authors: Keshavamurthy
authors: K
authors: Vinay
authors: Hiroshi
authors: H
authors: Koga
authors: Takashi
authors: T
authors: Hashimoto
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001323:Autoantibodies / Q000097:blood*; D015815:Cell Adhesion Molecules / Q000276:immunology*; D003622:Dapsone / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008875:Middle Aged; D010390:Pemphigoid, Benign Mucous Membrane / Q000097:blood* / Q000188:drug therapy / Q000276:immunology*; D011239:Prednisolone / Q000627:therapeutic use; D000097794:Kalinin
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D001323:Autoantibodies; D015815:Cell Adhesion Molecules; D003622:Dapsone; D007074:Immunoglobulin G; D011239:Prednisolone; D000097794:Kalinin