title: Pseudomonas aeruginosa bacteriophage PA1Ø requires type IV pili for infection and shows broad bactericidal and biofilm removal activities.
abstract: We isolated a new lytic Pseudomonas aeruginosa phage that requires type IV pili for infection. PA1Ø has a broad bactericidal spectrum, covering Gram-positive and Gram-negative bacteria, and can eradicate biofilm cells. PA1Ø may be developed as a therapeutic agent for biofilm-related mixed infections with P. aeruginosa and Staphylococcus aureus.
authors: Department of Microbiology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.
authors: Shukho
authors: S
authors: Kim
authors: Marzia
authors: M
authors: Rahman
authors: Sung Yong
authors: SY
authors: Seol
authors: Sang Sun
authors: SS
authors: Yoon
authors: Jungmin
authors: J
authors: Kim
mesh_terms: D001433:Bacteriolysis; D018441:Biofilms / Q000254:growth & development*; D001691:Biological Therapy / Q000379:methods; D010861:Fimbriae, Bacterial / Q000502:physiology*; D011552:Pseudomonas Infections / Q000628:therapy; D017105:Pseudomonas Phages / Q000254:growth & development / Q000502:physiology*; D011550:Pseudomonas aeruginosa / Q000502:physiology* / Q000821:virology*; D053586:Virus Internalization