title: Synthesis and fungicidal activity of novel 2,3-disubstituted-1,3-benzoxazines.
abstract: A series of new 2,3-disubstituted-3,4-dihydro-2H-1,3-benzoxazines were prepared in moderate to excellent yields by aza-acetalizations of aromatic aldehydes with 2-(N-substituted aminomethyl)phenols in the presence of TMSCl. Their structures were confirmed by IR, ¹H-NMR, ¹³C-NMR, MS and elemental analysis. The fungicidal activities of the target compounds were preliminarily evaluated, and some compounds exhibited good activity against Rhizoctonia solani.
authors: School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, China. zltang67@yahoo.com.cn
authors: Zilong
authors: Z
authors: Tang
authors: Zhonghua
authors: Z
authors: Zhu
authors: Zanwen
authors: Z
authors: Xia
authors: Hanwen
authors: H
authors: Liu
authors: Jinwen
authors: J
authors: Chen
authors: Wenjing
authors: W
authors: Xiao
authors: Xiaoming
authors: X
authors: Ou
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D048588:Benzoxazines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests
chemical_list: D000935:Antifungal Agents; D048588:Benzoxazines