title: Lab-in-a-tube: on-chip integration of glass optofluidic ring resonators for label-free sensing applications.
abstract: The fabrication of tubular rolled-up optofluidic ring resonators (RU-OFRRs) based on glass (SiO(2)) material with high quality factors is reported. A novel methodology combining lab-on-a-chip fabrication methods and rolled-up nanotech is presented for the fabrication of fully integrated tubular optofluidic sensors. The microfluidic integration of several RU-OFRRs on one chip is solved by enclosing the microtubes with a patterned robust SU-8 polymeric matrix. A viewport on each microtube enables exact excitation and monitoring of whispering gallery modes with a photoluminescence spectroscopy system under constant ambient conditions, while exchanging the content of the RU-OFRR with liquids of different refractive indices. The refractrometric sensor capabilities are investigated regarding signal stability, sensitivity and reliability. The sensitivity of the integrated RU-OFRR, which is the response of the modes to the change in refractive index of the liquid, is up to 880 nm/refractive index units (RIU).
authors: Institute for Integrative Nanosciences, IFW Dresden, Dresden, Germany. s.harazim@ifw-dresden.de
authors: Stefan M
authors: SM
authors: Harazim
authors: Vladimir A
authors: VA
authors: Bolaños Quiñones
authors: Suwit
authors: S
authors: Kiravittaya
authors: Samuel
authors: S
authors: Sanchez
authors: Oliver G
authors: OG
authors: Schmidt
mesh_terms: D004867:Equipment Design; D005898:Glass / Q000737:chemistry; D056656:Lab-On-A-Chip Devices; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation*; D036103:Nanotechnology / Q000295:instrumentation; D012031:Refractometry / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity