title: How to build a DNA unwinding machine.
abstract: In this issue of Structure, He and colleagues present the crystal structure of the phage T4 Dda helicase bound to DNA, providing new insights into how this protein efficiently couples single-stranded DNA translocation to DNA strand separation.
authors: DNA:Protein Interactions Unit, School of Biochemistry, Medical Sciences Building, University of Bristol, BS8 1TD, UK.
authors: Mark D
authors: MD
authors: Szczelkun
authors: Mark S
authors: MS
authors: Dillingham
mesh_terms: D017122:Bacteriophage T4 / Q000378:metabolism*; D004247:DNA / Q000737:chemistry*; D004265:DNA Helicases / Q000737:chemistry*; D004277:DNA, Single-Stranded / Q000737:chemistry*; D014764:Viral Proteins / Q000737:chemistry*
chemical_list: D004277:DNA, Single-Stranded; D014764:Viral Proteins; D004247:DNA; D004265:DNA Helicases; C077401:dda DNA helicase protein, Bacteriophage T4