title: Serotonin transport and synthesis systems during early development of invertebrates: functional analysis on a bivalve model. Short communication.
abstract: Serotonin (5.HT) is known to be functionally active during early development in both vertebrates and invertebrates. However, the presence of 5-HT and its synthesis and transport system has not yet been demonstrated in bivalve early development. The presence of 5-HT was immunochemically demonstrated at the cleavage stage of bivalve Mytilus trossulus. 5-HT level dramatically increased within all embryonic cells after incubation with 5-HTP but not after incubation with tryptophan and 5-HT. The first 5-HT uptake by specific transporter was detected at 13 hpf blastula stage only and it was restricted to one distinct cell.
authors: Department of Comparative Physiology, Institute of Developmental Biology RAS, Moscow, Russia. veliger@yandex.ru
authors: E G
authors: EG
authors: Ivashkin
authors: Marina Yu
authors: MY
authors: Khabarova
authors: Elena E
authors: EE
authors: Voronezhskaya
mesh_terms: D000818:Animals; D036703:Blastula / Q000378:metabolism; D049878:Mytilus / Q000196:embryology* / Q000378:metabolism*; D012701:Serotonin / Q000378:metabolism*
chemical_list: D012701:Serotonin