title: HIV screening practices for living organ donors, New York State, 2010: need for standard policies.
abstract: Our survey of kidney and liver transplant centers in New York State found a wide variation among transplant centers in evaluation and screening for HIV risk and infection among prospective living donors. Survey results underscore the need to standardize practices. A recent transmission of human immunodeficiency virus (HIV) from a living donor to a kidney recipient revealed a possible limitation in existing screening protocols for HIV infection in living donors. We surveyed kidney and liver transplant centers (N = 18) in New York State to assess HIV screening protocols for living donors. Although most transplant centers evaluated HIV risk behaviors in living donors, evaluation practices varied widely, as did the extent of HIV testing and prevention counseling. All centers screened living donors for serologic evidence of HIV infection, either during initial evaluation or ≥1 month before surgery; however, only 50% of transplant centers repeated HIV testing within 14 days before surgery for all donors or donors with specific risk behaviors. Forty-four percent of transplant centers used HIV nucleic acid testing (NAT) to screen either all donors or donors with recognized risk behaviors, and 55% never performed HIV NAT. Results suggest the need to standardize evaluation of HIV risk behaviors and prevention counseling in New York State to prevent acquisition of HIV by prospective living organ donors, and to conduct HIV antibody testing and NAT as close to the time of donation as possible to prevent HIV transmission to recipients.
authors: Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA. candicekwan@post.harvard.edu
authors: Candice K
authors: CK
authors: Kwan
authors: Teeb
authors: T
authors: Al-Samarrai
authors: Lou C
authors: LC
authors: Smith
authors: Charulata J
authors: CJ
authors: Sabharwal
authors: Kim A
authors: KA
authors: Valente
authors: Lucia V
authors: LV
authors: Torian
authors: Lisa M
authors: LM
authors: McMurdo
authors: Colin W
authors: CW
authors: Shepard
authors: John T
authors: JT
authors: Brooks
authors: Matthew J
authors: MJ
authors: Kuehnert
mesh_terms: D019411:Clinical Laboratory Techniques / Q000379:methods* / Q000592:standards*; D003430:Cross-Sectional Studies; D004279:DNA, Viral / Q000097:blood; D015483:HIV Antibodies / Q000097:blood; D015658:HIV Infections / Q000175:diagnosis*; D006291:Health Policy; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D009518:New York; D012367:RNA, Viral / Q000097:blood; D014019:Tissue Donors
chemical_list: D004279:DNA, Viral; D015483:HIV Antibodies; D012367:RNA, Viral