title: [Ethnic influence on the prevalence of metabolic syndrome in an obese pediatric population].
abstract: BACKGROUND
  Obesity in children is becoming more prevalent. Obesity and type 2 diabetes is higher in the Latin American immigrant population.
  
  
  OBJECTIVE
  To analyze the influence of ethnicity on the prevalence of metabolic syndrome (MS) and its components in an obese pediatric population.
  
  
  METHODS
  A retrospective study of 616 obese children and adolescents (BMI ≥2 SD [Hernández 88-04]), was conducted on 142 Latin American children and 474 Caucasians, which compared the prevalence of metabolic syndrome and its components according to modified Cook criteria (2003): obesity+2 or more of the following components: HDL-cholesterol <40mg/dl, triglycerides >110mg/dl, systolic and/or diastolic blood pressure >p90 (Task Force 2004), and impaired glucose metabolism (ADA 2011). Hepatic function, family history of MS, HbA1c, insulin resistance (HOMA) and BMI evolution at one year of treatment with changes in lifestyle (diet and exercise) were also assessed.
  
  
  RESULTS
  Almost one-third (30.5%) of Latin American children had MS compared to 15.5% of Caucasians (OR=2.4 [CI 95%: 1.5-3.8]), P<.005] and OR=2.5 adjusting for sex, SD-BMI and puberty. Latin American children also had a higher insulin resistance (58.6% vs 42.8%, P<.005) and a worse outcome after one year of treatment.
  
  
  CONCLUSIONS
  There is a higher prevalence of MS in our Latin American obese pediatric population with poor adherence to the measures of change in lifestyle, making these patients a group with potentially increased risks of cardiovascular disease in adulthood.
authors: Unidad de Diabetes y Endocrinología Pediátrica, Servicio de Pediatría, Hospital Universitario Ramón y Cajal, Universidad de Alcalá, Madrid, Spain. patrienes@msn.com
authors: P
authors: P
authors: Enes Romero
authors: B
authors: B
authors: Cano Gutiérrez
authors: N
authors: N
authors: Alvarez Gil
authors: M
authors: M
authors: Martín-Frías
authors: M
authors: M
authors: Alonso Blanco
authors: R
authors: R
authors: Barrio Castellanos
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D007843:Latin America; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000453:epidemiology* / Q000208:ethnology; D009765:Obesity / Q000150:complications*; D015995:Prevalence; D012189:Retrospective Studies; D044465:White People