title: Subcutaneous Nipple-Sparing Mastectomy and Immediate Breast Reconstruction.
abstract: BACKGROUND: Without a doubt, nipple-sparing mastectomy affords a better cosmetic result than modified radical mastectomy. However, the surgical safety, radicality, complications, indications, and psychological benefits associated with this method are controversially discussed.  PATIENTS AND METHODS: We carried out a retrospective analysis of 35 patients (study group) who underwent nipple-sparing mastectomy between 2000 and 2008. Indications, incision selection, postoperative complications, recurrence, morbidity rate, and psychological status were recorded and assessed.  RESULTS: The survival outcome (5.7 vs. 6%; p = 0.35) and complication rate (5.7 vs. 19%; p = 0.062) of patients who underwent subcutaneous nipple-sparing mastectomy and immediate breast reconstruction with prosthesis were similar to those of patients who underwent modified radical mastectomy. Most patients in the study group were completely satisfied with the aesthetic results (immediately, p < 0.001; < 1 year, p < 0.001; > 1 year, p < 0.001), and no serious psychological disorders or stress were detected relative to patients with traditional mastectomy.  CONCLUSION: Subcutaneous nipple-sparing mastectomy was beneficial and safe in this cohort of breast cancer patients. The approach is suitable for patients with isolated lesions located ≥ 2 cm from the nipple, as well as for patients with multiple lesions who are anxious about a good cosmetic appearance.
authors: Department of Breast Surgery, The First Hospital, Jilin University, Changchun, Jilin, P.R. China.
authors: Aiping
authors: A
authors: Shi
authors: Di
authors: D
authors: Wu
authors: Xingliang
authors: X
authors: Li
authors: Shifu
authors: S
authors: Zhang
authors: Sijie
authors: S
authors: Li
authors: Hui
authors: H
authors: Xu
authors: Huijun
authors: H
authors: Xie
authors: Zhimin
authors: Z
authors: Fan