title: Maternal carbon dioxide level during labor and its possible effect on fetal cerebral oxygenation: mini review.
abstract: During pregnancy, and especially during labor, the maternal carbon dioxide level declines considerably. Maternal carbon dioxide levels show a close relation with fetal carbon dioxide levels. The latter affects fetal cerebral oxygenation by regulating cerebral blood flow and shifting the oxyhemoglobin dissociation curve. In addition, maternal hypocapnia appears to impair placental oxygen transfer. Thus, maternal hyperventilation may interfere with optimal fetal cerebral oxygenation. Here, we provide a brief overview of the literature relevant to this issue.
authors: Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. tomimatsu@gyne.med.osaka-u.ac.jp
authors: Takuji
authors: T
authors: Tomimatsu
authors: Aiko
authors: A
authors: Kakigano
authors: Kazuya
authors: K
authors: Mimura
authors: Tomoko
authors: T
authors: Kanayama
authors: Shinsuke
authors: S
authors: Koyama
authors: Satoko
authors: S
authors: Fujita
authors: Yukiko
authors: Y
authors: Taniguchi
authors: Takeshi
authors: T
authors: Kanagawa
authors: Tadashi
authors: T
authors: Kimura
mesh_terms: D001921:Brain / Q000098:blood supply; D002245:Carbon Dioxide / Q000097:blood*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D005333:Fetus / Q000503:physiopathology; D006801:Humans; D006985:Hyperventilation / Q000503:physiopathology; D007743:Labor, Obstetric / Q000097:blood*; D008431:Maternal-Fetal Exchange / Q000502:physiology*; D010100:Oxygen / Q000097:blood*; D011247:Pregnancy
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen