title: [Rapid on-site evaluation (ROSE) in cytological diagnostics of pulmonary and mediastinal diseases].
abstract: Endobronchial ultrasound-guided transbronchial fine needle aspiration (EBUS-TBNA) has become an important tool in the diagnosis and staging of malignant tumors of the lungs and mediastinum. Rapid on-site evaluation (ROSE) denotes a cytomorphological diagnostic procedure that allows assessment of the adequacy and accuracy of the material obtained during bronchoscopy within a few minutes in or near the bronchoscopy suite (on-site) using a quick staining of smears. This results in a significant decrease in the number of repeated bronchoscopy procedures required to recover an adequate biopsy sample and is therefore both time and cost effective. The obtained material can be further assessed as conventional cytological specimens or alternatively using the thin-prep technique for definitive cytopathology diagnosis and/or embedded in paraffin for immunohistochemical or molecular analyses such as DNA sequencing or flow cytometry.
authors: Institut für Pathologie und Neuropathologie, Universitätsklinikum Essen, Universität Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Deutschland. jeremias.wohlschlaeger@uk-essen.de
authors: J
authors: J
authors: Wohlschläger
authors: K
authors: K
authors: Darwiche
authors: S
authors: S
authors: Ting
authors: T
authors: T
authors: Hager
authors: L
authors: L
authors: Freitag
authors: K W
authors: KW
authors: Schmid
authors: H
authors: H
authors: Kühl
authors: D
authors: D
authors: Theegarten
mesh_terms: D000465:Algorithms; D044963:Biopsy, Fine-Needle / Q000295:instrumentation; D001707:Biopsy, Needle; D001999:Bronchoscopy / Q000295:instrumentation; D003584:Cytological Techniques / Q000379:methods; D004867:Equipment Design; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000473:pathology; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008481:Mediastinoscopy; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D013996:Time and Motion Studies; D014057:Tomography, X-Ray Computed; D018084:Ultrasonography, Interventional / Q000295:instrumentation