title: Selective role of Mediator tail module in the transcription of highly regulated genes in yeast.
abstract: The tail module subunits of Mediator complex are targets of activators both in yeast and metazoans. Here we discuss recent evidence from studies in yeast for tail module specificity for SAGA-dependent, TATA-containing genes including highly regulated stress response genes, and for independent recruitment and function of the tail module.
authors: Laboratory of Molecular Genetics, Wadsworth Center, New York State Department of Health, Albany, NY, USA. sansari@wadsworth.org
authors: Suraiya A
authors: SA
authors: Ansari
authors: Randall H
authors: RH
authors: Morse
mesh_terms: D015966:Gene Expression Regulation, Fungal; D005809:Genes, Regulator; D056892:Mediator Complex / Q000235:genetics* / Q000378:metabolism; D011401:Promoter Regions, Genetic; D021122:Protein Subunits / Q000235:genetics / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000235:genetics* / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics* / Q000378:metabolism; D012641:Selection, Genetic; D013312:Stress, Physiological; D014158:Transcription, Genetic
chemical_list: D056892:Mediator Complex; D021122:Protein Subunits; D029701:Saccharomyces cerevisiae Proteins