title: An unusual variant of prostatic adenocarcinoma with metastasis to testis. A case report.
abstract: Ductal adenocarcinoma of the prostate is considered to be a rare variant of prostatic adenocarcinoma when compared to the more common acinar adenocarcinoma. We report here a case of ductal adenocarcinoma of the prostate in a 68-year old man who presented with complaints of abdominal pain, retention of urine and hematuria of one month duration. Clinical examination showed prostatomegaly. The serum Prostate Specific Antigen (PSA) value was raised to 79ng/mL. Histopathological and immunohistochemical evaluation of resected specimen of prostate revealed ductal adenocarcinoma of the prostate. The patient was lost to follow up and presented four years after the initial diagnosis with metastasis to the bone and testis. Though prostatic cancers have the ability for wide spread dissemination, metastasis to testis is rare. Immunohistochemical staining with PSA and Prostatic Acid Phosphatase (PAP) can help in establishing prostatic nature of the neoplasm. We are reporting this case because of the rarity of metastasis of prostatic carcinoma to testis and for stressing the need for keeping in mind the possibility of metastatic carcinoma also while dealing with testicular tumors.
authors: Department of Pathology, Regional Cancer Centre, Thiruvananthapuram, Kerala, India. venuanila@yahoo.com
authors: K R
authors: KR
authors: Anila
authors: T
authors: T
authors: Somanathan
authors: A
authors: A
authors: Mathews
authors: K
authors: K
authors: Jayasree
mesh_terms: D000135:Acid Phosphatase; D000230:Adenocarcinoma / Q000097:blood / Q000473:pathology*; D000368:Aged; D006801:Humans; D008297:Male; D017430:Prostate-Specific Antigen / Q000032:analysis; D011471:Prostatic Neoplasms / Q000097:blood / Q000473:pathology*; D017027:Protein Tyrosine Phosphatases / Q000097:blood; D013736:Testicular Neoplasms / Q000556:secondary*
chemical_list: D000135:Acid Phosphatase; C428439:prostatic acid phosphatase; D017027:Protein Tyrosine Phosphatases; D017430:Prostate-Specific Antigen