title: Cytotoxic and antigen presenting functions of T helper-1-activated dendritic cells.
abstract: Although primarily defined by their cardinal antigen-presenting function, dendritic cells (DCs) are also equipped with cytotoxic properties. We have recently reported that DCs activated by IFNγ-secreting Th-1 lymphocytes can kill cancer cells and subsequently present the acquired tumor-derived antigens to T lymphocytes both in vitro and in vivo.
authors: Department of Pediatrics; Steele Children's Research Center; Department of immunobiology; BIO5 Institute and Arizona Cancer Center; University of Arizona; Tucson, AZ USA.
authors: Nicolas
authors: N
authors: Larmonier
authors: Bernard
authors: B
authors: Bonnotte
authors: Emmanuel
authors: E
authors: Katsanis