title: Histoplasmosis among hospitalized febrile patients in northern Tanzania.
abstract: Histoplasmosis may be common in East Africa but the diagnosis is rarely confirmed. We report 9 (0.9%) cases of probable histoplasmosis retrospectively identified among 970 febrile inpatients studied in northern Tanzania. Median (range) age was 31 (6, 44) years, 6 (67%) were female, 6 (67%) HIV-infected; 7 (78%) were clinically diagnosed with tuberculosis or bacterial pneumonia. Histoplasmosis is an important cause of febrile illness in Tanzania but is rarely considered in the differential diagnosis. Increased clinician awareness and availability of reliable diagnostic tests may improve patient outcomes.
authors: Division of Infectious Diseases and International Health, Department of Medicine, Box 102359, Duke University Medical Center, Durham, NC 27710, USA.
authors: Sarah M
authors: SM
authors: Lofgren
authors: Emily J
authors: EJ
authors: Kirsch
authors: Venance P
authors: VP
authors: Maro
authors: Anne B
authors: AB
authors: Morrissey
authors: Levina J
authors: LJ
authors: Msuya
authors: Grace D
authors: GD
authors: Kinabo
authors: Wilbrod
authors: W
authors: Saganda
authors: Helmut C
authors: HC
authors: Diefenthal
authors: Habib O
authors: HO
authors: Ramadhani
authors: L Joseph
authors: LJ
authors: Wheat
authors: John A
authors: JA
authors: Crump
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D005334:Fever / Q000453:epidemiology* / Q000209:etiology*; D006679:HIV Seropositivity / Q000175:diagnosis / Q000453:epidemiology*; D006658:Histoplasma / Q000472:pathogenicity*; D006660:Histoplasmosis / Q000175:diagnosis / Q000453:epidemiology*; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D013636:Tanzania / Q000453:epidemiology; D014376:Tuberculosis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D055815:Young Adult