title: Molecular biology and clinical features of hereditary non-polyposis colorectal cancer.
abstract: Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominantly inherited disease associated with germ-line mutations in mismatch repair genes and microsatellite instability. This article reviews the molecular biology and clinical pathology of HNPCC.
authors: Department of Multimodality Therapy Oncology, Chinese PLA Hospital, Beijing 100853, China.
authors: Sha-sha
authors: SS
authors: Guan
authors: Guang-hai
authors: GH
authors: Dai
mesh_terms: D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D053843:DNA Mismatch Repair; D006801:Humans; D053842:Microsatellite Instability