title: Translational homeostasis via eIF4E and 4E-BP1.
abstract: In this issue of Molecular Cell, Yanagiya et al. (2012) describe a regulatory mechanism that couples the abundance of the translational repressor 4E-BP1 with its target eIF4E via proteasomal degradation of 4E-BP1, thus maintaining translation in cells depleted of eIF4E.
authors: Laboratory of Gene Regulation and Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA. ahinnebusch@nih.gov
authors: Alan G
authors: AG
authors: Hinnebusch