title: Right ventricular remodeling in pulmonary hypertension.
abstract: The right ventricle (RV) is in charge of pumping blood to the lungs for oxygenation. Pulmonary arterial hypertension (PAH) is characterized by high pulmonary vascular resistance and vascular remodeling, which results in a striking increase in RV afterload and subsequent failure. There is still unexploited potential for therapies that directly target the RV with the aim of supporting and protecting the right side of the heart, striving to prolong survival in patients with PAH.
authors: Department of Cardiovascular Disease, Pulmonary Hypertension and Adult Congential Heart Disease Program, Advanced Heart Failure and Transplantation Program, The Ohio State University, 473 West 12th Avenue, Columbus, OH 43210, USA. veronica.franco@osumc.edu
authors: Veronica
authors: V
authors: Franco
mesh_terms: D017079:Exercise Tolerance; D006305:Health Status Indicators; D006333:Heart Failure / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D006352:Heart Ventricles / Q000473:pathology*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D019028:Magnetic Resonance Imaging, Cine; D020097:Natriuretic Peptide, Brain; D010101:Oxygen Consumption; D014463:Ultrasonography; D016277:Ventricular Function, Left; D016278:Ventricular Function, Right; D020257:Ventricular Remodeling
chemical_list: D020097:Natriuretic Peptide, Brain