title: A novel mechanism for cancer cells to evade immune attack by NK cells: The interaction between NKp44 and proliferating cell nuclear antigen.
abstract: We recently reported proliferating cell nuclear antigen (PCNA) as a ligand for the NK cell activating receptor, NKp44, which unexpectedly triggers inhibition. The recognition of nuclear proteins such as PCNA, by related NK cell receptors has been reported. Widespread upregulation of PCNA in tumor cells may therefore promote immune evasion.
authors: The Shraga Segal Department of Microbiology and Immunology; Faculty of Health Sciences; Ben-Gurion University of the Negev; Beer Sheva, Israel.
authors: Benyamin
authors: B
authors: Rosental
authors: Uzi
authors: U
authors: Hadad
authors: Michael
authors: M
authors: Brusilovsky
authors: Kerry S
authors: KS
authors: Campbell
authors: Angel
authors: A
authors: Porgador