title: Neuroinvasive Mycoplasma pneumoniae infection without intrathecal antibody response.
abstract: The pathogenesis of extrapulmonary Mycoplasma pneumoniae-associated neurologic disease is unclear. We present a case of acute meningoencephalitis in a 15-year-old girl with central nervous system invasion of the bacterium but without intrathecal antibody synthesis. Our observations suggest that in this setting M. pneumoniae infection can be self-limiting and mild despite invasion of the central nervous system.
authors: Division of Infectious Diseases and Hospital Epidemiology, University Children's Hospital, Zurich, Switzerland. patrick.meyer@kispi.uzh.ch
authors: Patrick M
authors: PM
authors: Meyer Sauteur
authors: Benedikt M
authors: BM
authors: Huber
authors: Philippe
authors: P
authors: Goetschel
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000134:cerebrospinal fluid*; D017963:Azithromycin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology*; D009177:Mycoplasma pneumoniae / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D017963:Azithromycin