title: IFN-γ signals a changing of the guards.
abstract: After acute inflammation or infection, tissue-resident macrophages are replaced by inflammatory DCs and effector macrophages that arise from circulating monocytes. In this issue of Immunity, Goldszmid et al. (2012) demonstrate a central role for NK cell-derived IFN-γ in signaling and facilitating this transition.
authors: Center for Immunity and Inflammation, UMDNJ-New Jersey Medical School, Newark, NJ 07101, USA.
authors: George S
authors: GS
authors: Yap
authors: Amariliz
authors: A
authors: Rivera