title: Anti-NMDA receptor encephalitis with associated catatonia during pregnancy.
abstract: Anti-NMDA-R encephalitis has been described as a cause of acute psychosis in young females. It is rare during pregnancy. We describe a primigravida 32-year-old woman with acute onset psychosis during the first trimester. Eight weeks after becoming pregnant, the patient became psychotic with associated catatonia and autonomic disturbance. Serum anti-NMDA-R antibodies were found. She responded to plasma exchange. At caesarean section, a healthy baby boy was born and a benign mature cystic teratoma was removed from the left ovary. Catatonia associated with psychosis may occur in pregnancy secondary to anti-NMDA-R encephalitis. Prompt and aggressive treatment can lead to a good outcome for both baby and mother.
authors: Dublin Neurological Institute at the Mater Misericordiae University Hospital, 57 Eccles Street, Dublin 7, Ireland. amaccarthy@gmail.com
authors: A
authors: A
authors: McCarthy
authors: J
authors: J
authors: Dineen
authors: P
authors: P
authors: McKenna
authors: M
authors: M
authors: Keogan
authors: J
authors: J
authors: Sheehan
authors: T
authors: T
authors: Lynch
authors: K
authors: K
authors: O'Rourke
mesh_terms: D000328:Adult; D060426:Anti-N-Methyl-D-Aspartate Receptor Encephalitis / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D002389:Catatonia / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010951:Plasma Exchange / Q000379:methods; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000628:therapy