title: Antiproliferative effects of fresh and thermal processed green and red cultivars of curly kale (Brassica oleracea L. convar. acephala var. sabellica).
abstract: Brassica vegetables contain a diverse range of phytochemicals with biological properties such as antioxidant and anticancer activity. However, knowledge about how biological activities are affected by processing is lacking. A green cultivar and a red cultivar of curly kale were evaluated for water/methanol-soluble phytochemicals before and after processing involving blanching, freeze storage, and boil-in-bag heat treatment. In both kale cultivars, processing resulted in a significant decrease of total phenolics, antioxidant capacity, and content and distribution of flavonols, anthocyanins, hydroxycinnamic acids, glucosinolates, and vitamin C. Interestingly, the red curly kale cultivar had a higher capacity to withstand thermal loss of phytochemicals. The extracts of both green and red curly kale inhibited the cell proliferation of three human colon cancer cell lines (Caco-2, HT-29, and HCT 116). However, extracts from fresh plant material had a significantly stronger antiproliferative effect than extracts from processed plant material.
authors: Nofima, Norwegian Institute of Food, Fisheries and Aquaculture Research , Osloveien 1, NO-1430 Ås, Norway.
authors: Helle
authors: H
authors: Olsen
authors: Stine
authors: S
authors: Grimmer
authors: Kjersti
authors: K
authors: Aaby
authors: Shikha
authors: S
authors: Saha
authors: Grethe Iren A
authors: GI
authors: Borge
mesh_terms: D000872:Anthocyanins / Q000032:analysis; D000970:Antineoplastic Agents / Q000032:analysis*; D000975:Antioxidants / Q000032:analysis; D017209:Apoptosis / Q000187:drug effects; D001205:Ascorbic Acid / Q000032:analysis; D001937:Brassica / Q000737:chemistry*; D018938:Caco-2 Cells; D049109:Cell Proliferation / Q000187:drug effects*; D002851:Chromatography, High Pressure Liquid; D003373:Coumaric Acids / Q000032:analysis; D005511:Food Handling / Q000379:methods*; D005961:Glucosinolates / Q000032:analysis; D045325:HCT116 Cells; D019073:HT29 Cells; D006801:Humans; D018515:Plant Leaves / Q000737:chemistry; D014675:Vegetables / Q000737:chemistry*
chemical_list: D000872:Anthocyanins; D000970:Antineoplastic Agents; D000975:Antioxidants; D003373:Coumaric Acids; D005961:Glucosinolates; D001205:Ascorbic Acid