Focal nodular hyperplasia with major sinusoidal dilatation: a misleading entity.
Focal nodular hyperplasia (FNH) is a benign liver lesion thought to be a non-specific response to locally increased blood flow. Although the diagnosis of FNH and hepatocellular adenoma (HCA) has made great progress over the last few years using modern imaging techniques, there are still in daily practice some difficulties concerning some atypical nodules. Here, the authors report the case of a 47-year-old woman with a single liver lesion thought to be, by imaging, an inflammatory HCA with major sinusoidal congestion. This nodule was revealed to be, at the microscopical level and after specific immunostaining and molecular analysis, an FNH with sinusoidal dilatation (so-called telangiectatic focal nodular hyperplasia).
Radiology Department, Hôpital St André CHU Bordeaux, Bordeaux, France. herve.laumonier@chu-bordeaux.fr
Hervé
H
Laumonier
Nora
N
Frulio
Christophe
C
Laurent
Charles
C
Balabaud
Jessica
J
Zucman-Rossi
Paulette
P
Bioulac-Sage
D018248:Adenoma, Liver Cell / Q000473:pathology; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D004108:Dilatation, Pathologic / Q000473:pathology / Q000601:surgery; D005260:Female; D020518:Focal Nodular Hyperplasia / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007089:Image Enhancement; D008099:Liver / Q000098:blood supply* / Q000473:pathology / Q000601:surgery; D008113:Liver Neoplasms / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D013684:Telangiectasis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery