[Application of diffusion tensor imaging and 1H-magnetic resonance spectroscopy in diagnosis of traumatic brain injury].
Mild traumatic brain injury (mTBI) is a common type of brain disorders among young adults. The dysfunction of the brain is often exacerbated due to diffuse axonal injury (DAI) which based on the injury of white matter fibers and axons. Since mild and moderate brain injury or DAI are diffuse and subtle, conventional CT and MRI are difficult to make a positive diagnosis. Recent clinical study indicated that functional magnetic resonance imaging has a high detection rate in the diagnosis of acute mild and moderate brain injury, especially the diffusion tensor imaging (DTI) and 1H-magnetic resonance spectroscopy (1H-MRS). This paper has reviewed the principles and characteristics of DTI and 1H-MRS, and recent research in the clinical and animal experiments on brain injury.
Department of Forensic Medicine, Kunming Medical University, Kunming 650500, China. 327164152@qq.com
Zhao
Z
Zhao
Jian-yun
JY
Yu
Kun-hua
KH
Wu
Hua-lin
HL
Yu
Ao-xiang
AX
Liu
Yu-hua
YH
Li
D000818:Animals; D001369:Axons / Q000473:pathology; D001921:Brain / Q000473:pathology*; D001924:Brain Concussion / Q000175:diagnosis / Q000473:pathology; D001930:Brain Injuries / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D020833:Diffuse Axonal Injury / Q000175:diagnosis* / Q000473:pathology; D056324:Diffusion Tensor Imaging; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D012720:Severity of Illness Index