Deoxidation of fenthion sulfoxide, fenthion oxon sulfoxide and fensulfothion in gas chromatograph/mass spectrometer, and the prevention of sulfoxide deoxidation by polyethylene glycol 300.
Fenthion, fenthion sulfoxide, fenthion oxon sulfoxide and fensulfothion showed two different mass spectra in GC/MS, depending on their concentrations.  The base peaks shifted to lower levels by 1 m/z at lower concentration, and no retention time shifts were observed.  The "shifted base peaks" were not obtained by a general EI fragmentation.  The product ion scan spectra of the "shifted base peaks" were coincident with those of molecular ions of their corresponding sulfides.  These phenomena can be ascribed to the conversion of sulfoxide into sulfide by the dominant deoxidation reaction than EI fragmentation in an ion source.  Adding polyethylene glycol 300 (PEG300) into a test solution prevented sulfoxide deoxidation.
Agilent Technologies Japan, Ltd, Hachioji, Tokyo, Japan. kuniyo_sugitate@agilent.com
Kuniyo
K
Sugitate
Takashi
T
Yamagami
Sadao
S
Nakamura
Akira
A
Toriba
Kazuichi
K
Hayakawa
D005284:Fenthion / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D007267:Injections; D009946:Organothiophosphorus Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D011092:Polyethylene Glycols / Q000737:chemistry*; D012451:Safrole / Q000031:analogs & derivatives* / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D013696:Temperature
D009946:Organothiophosphorus Compounds; D012997:Solvents; D011092:Polyethylene Glycols; D005284:Fenthion; D012451:Safrole; C073264:fensulfothion; C005746:sulfoxide