NanoPARCEL: a method for controlling cellular behavior with external light.
We developed a simple preparation procedure for the protein encapsulated nanoparticle and used the nanoparticle for spatiotemporal activity control of various proteins. We succeeded in the local protein activation within cells by light using the nanoparticle.
Graduate School of Pharmaceutical Sciences and Global COE Program, The University of Tokyo, 7-3-1 Hongo, Tokyo, Japan.
Shuhei
S
Murayama
Baowei
B
Su
Kohki
K
Okabe
Akihiro
A
Kishimura
Kensuke
K
Osada
Masayuki
M
Miura
Takashi
T
Funatsu
Kazunori
K
Kataoka
Masaru
M
Kato
D002214:Capsules / Q000138:chemical synthesis / Q000737:chemistry* / Q000528:radiation effects; D002477:Cells / Q000378:metabolism / Q000528:radiation effects*; D008027:Light; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*
D002214:Capsules; D011506:Proteins