Does milk fortification increase the risk of necrotising enterocolitis in preterm infants with congenital heart disease?
Prematurity and low birth weight adds to the risk of serious congenital heart disease in infants. It may also delay surgical intervention, especially when cardiopulmonary bypass is required, or where an aortopulmonary shunt is necessary to maintain adequate oxygenation. In this setting, neonatologists are faced with the challenge of accelerating the infant's growth to allow for early surgery. We describe the cases of two infants in whom an attempt to fortify the feeds was associated with necrotising enterocolitis, with a lethal outcome in one. The outcome suggests caution in fortifying feeds in premature infants with serious congenital heart disease.
Monash Newborn, Monash Medical Centre, Melbourne, Australia. atul.malhotra@monash.edu
Atul
A
Malhotra
Alex
A
Veldman
Samuel
S
Menahem
D000818:Animals; D020345:Enterocolitis, Necrotizing / Q000139:chemically induced*; D017809:Fatal Outcome; D005526:Food, Formulated / Q000009:adverse effects*; D006330:Heart Defects, Congenital / Q000150:complications* / Q000601:surgery; D006801:Humans; D007225:Infant Food / Q000009:adverse effects*; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D008892:Milk / Q000009:adverse effects*