Malignant peritoneal mesothelioma presented as peritoneal adenocarcinoma or primary ovarian cancer: case series and review of the clinical and immunohistochemical features.
Diffuse peritoneal malignant mesothelioma is a rare, progressive, and ultimately fatal disease and it can present as primary peritoneal carcinoma or ovarian cancer. Differential diagnosis is important to establish appropriate management. In this article the clinical presentation, immunuhistochemical and histopathological features of 8 diffuse peritoneal malignant mesothelioma cases presented as peritoneal carcinoma or ovarian cancer are evaluated. According to findings of all reported cases, we concluded that clinical distinction of malignant mesothelioma from ovarian cancer or peritoneal adenocarcinoma is very difficult. Differential diagnosis is reliably achieved by immune profile of the tumors with a systematic approach of both positive and negative mesothelioma markers.
Department of Obstetrics and Gynecology, Ankara University School of Medicine, Ankara, Turkey. salihtaskin@yahoo.com
Salih
S
Taşkın
Yeliz
Y
Gümüş
Saba
S
Kiremitçi
Korhan
K
Kahraman
Ayşe
A
Sertçelik
Fırat
F
Ortaç
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000378:metabolism; D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000378:metabolism; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008654:Mesothelioma / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D010534:Peritoneal Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D016896:Treatment Outcome
D014408:Biomarkers, Tumor