Gold in total synthesis: alkynes as carbonyl surrogates.
Fields of gold: Recent developments in the field of gold catalysis, using an alkyne as a carbonyl equivalent is becoming an important chemical transformation, thus providing flexibility in synthetic planning of complex and sensitive natural products. Understanding of the reaction and new catalyst designs are providing new conditions that are amenable for late-stage synthetic intermediates.
Department of Chemistry, Roanoke College, Salem, VA 24153, USA. brenzovich@roanoke.edu
William E
WE
Brenzovich