Evaluating the potential of quantum dots for in vitro biological studies: effects on gene expression using microarray analysis.
Quantum dots have potential applications in the biomedical field and especially in bioimaging owing to their tunable fluorescent properties. Although many phenotypic studies have been carried out using QDs on different cell lines, only very few of them involved the analysis of the effect of QDs on gene expression. Here, we describe the application of microarray gene expression analysis for studying the differential expression of genes in the cells treated with QDs.
National Centre for Biomedical Engineering Science, National University of Ireland, Galway, Ireland.
Babu R
BR
Prasad
Enda
E
O'Connell
Terry J
TJ
Smith
Valérie A
VA
Gérard
Yurii K
YK
Gun'ko
Yury
Y
Rochev
D000818:Animals; D002461:Cell Line, Transformed; D002470:Cell Survival; D015870:Gene Expression; D020869:Gene Expression Profiling; D006801:Humans; D046228:Microarray Analysis; D045663:Quantum Dots