Successful use of low molecular weight heparin in intracardiac thrombus of an extremely low birth weight infant.
The sick premature infants have high risk for thrombosis. Although therapeutic options include close observation, anticoagulation, thrombolytic therapy, and thrombectomy, guidelines for the management of neonatal arterial and venous thrombosis vary greatly among different centers. The authors report their experience using low molecular weight heparin (enoxaparin), with safe and successful resolution of right atrial thrombus, in an extremely low birth weight infant.
Department of Pediatrics, School of Medicine, Chungnam National University, 282 Munwharo, Jung-gu, Daejeon 301-721, Korea.
Ji-hye
JH
Shin
Gee-na
GN
Kim
Hong-ryang
HR
Kil
Mea-young
MY
Chang
D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004452:Echocardiography; D017984:Enoxaparin / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006325:Heart Atria; D006331:Heart Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D052577:Infant, Extremely Low Birth Weight; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000188:drug therapy; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014310:Triplets
D017984:Enoxaparin