Symptomatic gastric sarcoidosis in a patient with pulmonary sarcoidosis in remission.
Sarcoidosis is a multisystem, non-infectious, granulomatous disease of unknown cause, characterised by histological evidence of non-caseating granulomas. Gastrointestinal (GI) involvement is uncommon, reported in <1% of patients with the disease. Herein, we present a rare case of isolated gastric sarcoidosis in a patient with latent pulmonary sarcoidosis and unexplained manifestations of GI disease, illustrating that clinical disease expression is variable; may be organ-specific; and, known disease latency confined to one organ does not exclude the possibility of active disease in another organ system. In patients with organ-specific sarcoidosis, whether active or in remission, presenting with GI symptoms, the possibility of gastric sarcoidosis should be considered. Oesophagogastroduodenoscopy and biopsy, when indicated, should be considered for definitive diagnosis.
Department of Medicine, Lahey Clinic Medical Center, Burlington, Massachusetts, USA.
Lauren E
LE
Shkolnik
Reuben D
RD
Shin
David M
DM
Brabeck
Richard D
RD
Rothman
D015746:Abdominal Pain / Q000209:etiology; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001741:Black or African American; D016145:Endoscopy, Digestive System; D006801:Humans; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D012507:Sarcoidosis / Q000150:complications* / Q000175:diagnosis*; D017565:Sarcoidosis, Pulmonary / Q000150:complications* / Q000188:drug therapy; D013272:Stomach Diseases / Q000150:complications* / Q000175:diagnosis*; D016896:Treatment Outcome; D014839:Vomiting / Q000209:etiology
D000305:Adrenal Cortex Hormones