[Pathology and neurophysiology analysis for peripheral neuropathy of four patients with chemicals poisoning].
OBJECTIVE
To study the nerve electromyogram results by analysing the pathological characters of 4 cases diagnosed as peripheral neuropathy caused by n-hexane and arsenic.


METHODS
The nerve electromyogram examination and pathology data of 4 patients, who had been diagnosed as toxic chemicals peripheral neuropathy, were studied retrospectively.


RESULTS
Two patients in this group were exposed to n-hexane, their nerve electromyogram examinations and biopsy pathology of superficial peroneal nerve indicated the peripheral neuropathy was mainly manifests the lesion of medullary sheath. Another two patients were exposed to arsenic, their nerve electromyogram examinations showed axonal degeneration associated with demyelination, and their biopsy pathology showed the peripheral neuropathy was mainly axonal degeneration.


CONCLUSIONS
Axonal degeneration and demyelination always coexist in peripheral neuropathy caused by chemicals.
Shanghai Pumonary Hospital, Tongji University, China.
Jing-bo
JB
Zhang
Qiao-yun
QY
Zhang
Yong
Y
Wang
Dao-yuan
DY
Sun
D020261:Arsenic Poisoning / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006586:Hexanes / Q000506:poisoning*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced / Q000473:pathology* / Q000503:physiopathology*; D012189:Retrospective Studies; D055815:Young Adult
D006586:Hexanes; C026385:n-hexane