Bilateral corneal edema secondary to amantadine in the pediatric population: a case report.
OBJECTIVE
To report a case of amantadine induced corneal edema in a pediatric patient.


METHODS
A comprehensive ophthalmologic evaluation was performed to a 16-year-old female patient who presented with bilateral, painless loss of vision and corneal edema.


RESULTS
Review of the patient's medical information revealed the use of amantadine to alleviate extrapyramidal side effects secondary to psychiatric medications. Complete resolution of bilateral corneal edema was achieved one month after cessation of amantadine therapy.


CONCLUSIONS
Amantadine induced corneal edema should be considered in the differential diagnosis of bilateral corneal edema in all age groups. Review of the toxic side effects of systemic medications should be performed in every patient who presents with bilateral corneal edema.
Department of Ophthalmology, University of Puerto Rico, School of Medicine, Medical Sciences Campus, Puerto Rico. luis.santiago.caban@gmail.com
Luis A
LA
Santiago-Cabán
Enrique
E
Rivera
Vanessa
V
López-Beauchamp
D000293:Adolescent; D000547:Amantadine / Q000009:adverse effects*; D015715:Corneal Edema / Q000139:chemically induced* / Q000473:pathology; D015259:Dopamine Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans
D015259:Dopamine Agents; D000547:Amantadine