Protective mechanisms of green tea polyphenols in skin.
Skin is frequently exposed to a variety of environmental, chemical, and genotoxic agents that contribute to disease and carcinogenesis. Ultraviolet light (UVR) is the main external stress that leads to immunosuppression, oxidative stress, premature aging, and tumor formation. Scientists and health professionals emphasize the importance of prevention strategies to circumvent such unfavorable outcomes. Plant polyphenols are a promising approach to disease prevention and treatment. Green tea is an abundant source of plant polyphenols that exhibit significant antioxidant, chemopreventive, and immunomodulatory effects in protecting the skin.
Department of Dermatology, University Hospitals Case Medical Center, Cleveland, OH 44106-5028, USA.
Patricia
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OyetakinWhite
Heather
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Tribout
Elma
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Baron
D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000633:toxicity; D018890:Chemoprevention; D006801:Humans; D059808:Polyphenols / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D020011:Protective Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D012867:Skin / Q000187:drug effects* / Q000473:pathology / Q000528:radiation effects; D013662:Tea / Q000737:chemistry*
D000975:Antioxidants; D059808:Polyphenols; D020011:Protective Agents; D013662:Tea