Effect of perfluorodecalin on viability of Ehrlich ascites tumor cells under conditions of hypoxia.
Perfluorodecalin increased survival rate of Ehrlich ascites tumor cells under pathological conditions of hypoxia in combination with hyperkalemia. High potassium medium increased the content of lysophospholipids in samples, while in the presence of perfluorodecalin, phosphatidylethanolamine level decreased.
Al-Farabi Kazakh National University, Almaty, Kazakhstan.
Zh B
ZhB
Sabyrbek
O M
OM
Alekseeva
S T
ST
Tuleukhanov
Yu A
YA
Kim
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000503:physiopathology*; D002470:Cell Survival / Q000187:drug effects*; D002855:Chromatography, Thin Layer; D005466:Fluorocarbons / Q000494:pharmacology*; D006801:Humans; D006947:Hyperkalemia / Q000503:physiopathology*; D000860:Hypoxia / Q000503:physiopathology*; D008246:Lysophospholipids / Q000378:metabolism*; D010714:Phosphatidylethanolamines / Q000378:metabolism
D005466:Fluorocarbons; D008246:Lysophospholipids; D010714:Phosphatidylethanolamines; C483858:phosphatidylethanolamine; C008805:perfluorodecalin