Transsphenoidal approach for pituitary adenomas in patients with McCune-Albright syndrome.
The feasibility of transsphenoidal approach under a guidance of neuronavigation was explored to remove pituitary adenomas for patients with McCune-Albright syndrome (MAS). From August, 2008 to July, 2010, there were 5 patients diagnosed with MAS associated with a pituitary adenoma in our department of Peking Union Medical College Hospital. All the patients underwent transsphenoidal surgery for the removal of pituitary adenomas with the assistant of neuronavigation and all the procedures went uneventfully. Four of the five patients have got cured radiologically by imaging and 3 of them have got cured based on endocrinological criteria. Transsphenoidal approach under the neuronavigational guidance is a safe and effective management for the MAS patients with pituitary adenomas.
Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, No.1 Shuaifuyuan, Dongcheng District, Beijing 100730, People's Republic of China.
Wanchen
W
Dou
Xiao
X
Di
Renzhi
R
Wang
Huijuan
H
Zhu
Yong
Y
Yao
Kan
K
Deng
Ming
M
Feng
Guilin
G
Li
Junji
J
Wei
D000236:Adenoma / Q000175:diagnosis* / Q000601:surgery; D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005359:Fibrous Dysplasia, Polyostotic / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult