[Efficacy of mexidol in the combination with thrombolytic therapy in patients with ischemic stroke].
Comparative efficiency of ethylmethylhydroxypyridine succinate (Mexidol) in combination with thrombolytic therapy in patients with ischemic stroke was studied in 116 patients. All patients divided into 2 groups: group (46 patients) received thrombolysis with mexidol and group (70 patients) received thrombolysis with standard therapy. These results showed that the synergy this one therapy leads to significantly faster normalize acute indicators, which correlated with the degree of reduction the neurological deficiency. Thus, the results showed that the synergistic therapy creates the conditions not only for the restoration of neurological status, but also to prevent secondary brain damage.
Zh Iu
ZhIu
Chefranova
T A
TA
Makotrova
V A
VA
Udachin
E V
EV
Koledintseva
D000368:Aged; D004359:Drug Therapy, Combination; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010847:Picolines / Q000627:therapeutic use*; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D020521:Stroke / Q000188:drug therapy* / Q000517:prevention & control; D016896:Treatment Outcome
D005343:Fibrinolytic Agents; D010847:Picolines; D011619:Psychotropic Drugs; C070020:emoxypine succinate