Modulatory effect of the lectin-binding component, added to gel, on adhesion of yeast-like Candida fungi in vivo.
The lectin-binding component added to gel was studied in vivo as a potential therapeutic and preventive agent in experimental vaginal candidiasis. Laboratory studies demonstrated its antimycotic effect in relapsing vaginal candidiasis in mice.
Department of Microbiology and Virology, Department of Common Pharmaceutical and Biomedical Technology, Peoples' Friendship University of Russia, Moscow, Russia. anohinairina@yandex.ru
I V
IV
Anokhina
E G
EG
Kravtsov
N P
NP
Sachivkina
N V
NV
Yashina
M V
MV
Dalin
O A
OA
Semkina
D000818:Animals; D001426:Bacterial Proteins / Q000494:pharmacology* / Q000627:therapeutic use; D002176:Candida albicans / Q000187:drug effects / Q000502:physiology*; D002177:Candidiasis / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D005782:Gels / Q000494:pharmacology / Q000627:therapeutic use; D054884:Host-Pathogen Interactions; D051379:Mice; D009092:Mucous Membrane / Q000382:microbiology; D014627:Vaginitis / Q000188:drug therapy* / Q000382:microbiology
D001426:Bacterial Proteins; D005782:Gels