Study of fine needle aspiration cytology of breast lumps and its histopathological correlation in Pokhara Valley.
Breast carcinoma is the leading cause of cancer death in women. Most of the time breast carcinoma presents as breast lump. Fine Needle Aspiration Cytology (FNAC) is a convenient and rapid preoperative diagnostic procedure. This is a prospective and correlative study done in department of Pathology of Manipal Teaching Hospital, Pokhara from December 2003 to December 2005. FNAC was performed in patients presenting with breast lump and its findings were correlated with histopathological findings. Out of total 343 cases of breast FNAC, 73 cases had histopathology correlation. Age group of the patient ranged from 17 to 84 years. Breast lumps were most commonly seen in age group 21 to 30 years which comprises of benign lesions. Maximum number of malignancy (26%) was seen in age group 41 to 50 years. Out of 73 cases, malignancy was seen in 15 cases (20.5%). The most common carcinoma was Invasive Ductal Carcinoma (IDC) with 46.7% cases. With correlation of FNAC and histopathology, the sensitivity and specificity of both benign and malignant lesions were high. In malignant lesions, the sensitivity and specificity were 93.3% and 100% respectively. FNAC is a safe diagnostic procedure in the preoperative diagnosis of breast lumps in our setting. It gives the accurate result with proper technique and interpretation.
Department of Pathology, Nepal Medical College, Jorpati, Kathmandu, Nepal. sujatap2000@yahoo.com
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Pudasaini
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Talwar
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D001943:Breast Neoplasms / Q000473:pathology*; D002277:Carcinoma / Q000473:pathology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D009390:Nepal; D012680:Sensitivity and Specificity; D055815:Young Adult