Prestroke antihypertensive therapy: effect on the outcome.
About 70% of stroke patients have a history of hypertension. Patients with hypertension prior to stroke onset have higher blood pressure in the acute phase of stroke than non-hypertensive individuals. High blood pressure in the acute stroke adversely affects outcome. We analyzed 30-days outcome in 1306 hypertensive patients with ischemic stroke, of which 1069 (81.8%) received antihypertensive treatment before stroke onset. Multivariate logistic regression revealed that prestroke use of antihypertensives is an independent predictor of better stroke outcome, in terms of dependency and death or dependency. We conclude that increased efforts toward optimizing hypertension diagnostics and control are needed.
2nd Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland. kgrabska@ipin.edu.pl
Katarzyna
K
Grabska
Grażyna
G
Gromadzka
Anna
A
Członkowska
D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D002545:Brain Ischemia / Q000401:mortality / Q000517:prevention & control; D016208:Databases, Factual; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000401:mortality*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012189:Retrospective Studies; D020521:Stroke / Q000401:mortality* / Q000517:prevention & control*; D016896:Treatment Outcome
D000959:Antihypertensive Agents