Subtype-selective dopamine receptor radioligands for PET imaging: current status and recent developments.
This review presents a general overview of the subtype-selective dopamine receptor radioligands for in vivo imaging of dopamine receptor expression by positron emission tomography (PET). Besides the (11)C- and (18)F-labeled radioligands which are already in clinical use, a summary of subtype-selective radioligands which had been studied in vitro and in vivo is provided, which shines light onto the current status and recent developments in this field of radiopharmaceutical research.
Laboratory of Molecular Imaging and Radiochemistry, Nuclear Medicine Clinic, Friedrich-Alexander University, Schwabachanlage 6, D-91054 Erlangen, Germany.
A
A
Banerjee
O
O
Prante
D001921:Brain / Q000000981:diagnostic imaging / Q000378:metabolism; D006801:Humans; D008024:Ligands; D049268:Positron-Emission Tomography; D020033:Protein Isoforms / Q000737:chemistry / Q000378:metabolism; D019275:Radiopharmaceuticals / Q000737:chemistry; D011954:Receptors, Dopamine / Q000737:chemistry* / Q000378:metabolism
D008024:Ligands; D020033:Protein Isoforms; D019275:Radiopharmaceuticals; D011954:Receptors, Dopamine