[Endovascular treatment for venous sinus stenosis in idiopathic intracranial hypertension].
OBJECTIVE
To explore the relationship of venous sinus stenosis and idiopathic intracranial hypertension (IIH) and to discuss the efficacy and strategy of endovascular treatment.


METHODS
Balloon angioplasty and stent placement were performed in 24 IIH cases by lateral sinus stenosis. Mechanical thrombus maceration was performed before stent placing in 5 cases with suspected chronic dural sinus thrombosis. The clinical data of clinical presentations, intracranial pressure, pressure of lateral sinus, pressure gradient between distal and proximal lateral sinus stenosis, methods of treatment and therapeutic outcomes were retrospectively analyzed.


RESULTS
Intracranial pressure dropped from (314 ± 56) mm H2O of pre-operation to (197 ± 31) mm H2O of post-operation. The post-treatment pressure gradient was obviously high ((159 ± 11) mm H2O) and a reduction was found ((95 ± 11) mm H2O). Headache in 16 cases, vision in 13 and papilledema in 10 were resolved or improved. There was no other permanent procedure-related morbidity. The patients were followed up for 2 - 19 months. And no in-stent restenosis occurred.


CONCLUSIONS
Endovascular treatment is effective for IIH by venous sinus stenosis.
Department of Neurology, Guangdong Provincial General Hospital, Guangdong Neuroscience Institute, Guangdong Academy of Medical Sciences, Guangzhou 510080, China.
Chi-zhong
CZ
He
Xun-ming
XM
Ji
Li-juan
LJ
Wang
Xin-tong
XT
Liu
Xiong
X
Zhang
Shuo
S
Wang
Jian
J
Chen
Feng
F
Ling
D000328:Adult; D019917:Blood Vessel Prosthesis Implantation; D002533:Cerebral Angiography; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011559:Pseudotumor Cerebri / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D012851:Sinus Thrombosis, Intracranial / Q000150:complications / Q000601:surgery*; D015607:Stents; D055815:Young Adult