Evolutionary routes from a prebiotic ANA-world.
Recent experimental support has been generated for a model of prebiotic development that postulates a role for Amyloid-Nucleic Acid (ANA)-fibers as the earliest replicating entities capable of undergoing Darwinian evolution. Here, this new model is compared with existing RNA-world models with a particular focus on trajectories that lead to evolutionary-beneficial interactions between nucleic acid, protein and lipid components. This analysis suggests a number of new areas for fruitful experimental studies.
School of Bioscience; Cardiff University; Cardiff, Wales UK.
Sebastian
S
Braun
Christine
C
Humphreys
Trevor C
TC
Dale