Mycophenolate mofetil associated with progressive multifocal leukoencephalopathy with successful outcome.
The use of mycophenolate mofetil (MMF) is known to be associated with progressive multifocal leukoencephalopathy (PML). We report a case of PML in a patient receiving MMF, who showed improvement upon discontinuation of the drug. He was restarted on MMF, following which he went into coma. He showed prompt recovery upon stopping the drug again and made full recovery without any residual neurological deficit. This case is being reported to further highlight this neurological side-effect of MMF.
Military Hospital of Instruction Mohammed V, Rabat, Morocco. delkabbaj@yahoo.fr
Driss
D
El Kabbaj
Mohammed
M
Hassani
Mouncif
M
Kadiri
Jamal
J
Mounach
Hamid
H
Ouhabi
Charki
C
Haimeur
Zouhir
Z
Oualim
D000328:Adult; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation; D007968:Leukoencephalopathy, Progressive Multifocal / Q000139:chemically induced*; D008279:Magnetic Resonance Imaging; D008297:Male; D009173:Mycophenolic Acid / Q000009:adverse effects / Q000031:analogs & derivatives*; D016896:Treatment Outcome
D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid