Effect of elapsed time from coronary angiography until off-pump coronary artery bypass surgery on postoperative renal function.
BACKGROUND
A new concern in acute kidney injury (AKI) following coronary artery bypass grafting (CABG) is the elapsed time from coronary angiography (CAG) until subsequent surgery. This study aimed to retrospectively evaluate renal function following elective off-pump CABG (OPCAB).


RESULTS
Three hundred and seven patients were divided either into group A (elapsed time between CAG and surgery ≤5 days, n=138) or B (elapsed time >5 days, n=169). The estimated glomerular filtration rate (eGFR) was obtained on the 1st, 3rd and 7th day following CABG. The pre-, intra-and postoperative relevant data were analyzed. 51 patients (16.6%) developed postoperative AKI. Patients with shorter elapsed time were more likely to present postoperative AKI than those with a longer elapsed time (23.9% vs. 10.7%, P=0.003). Multivariate logistic regression analysis showed that elapsed time had an independent influence on the development of postoperative AKI (odds ratio 2.35, 95% confidence interval 1.45-5.26, P=0.009). The eGFR reduced gradually after surgery, dropped to a minimum within 3 days, and then increased slowly in both groups. Minimum eGFR following surgery in group B was significantly higher than that in group A (64.3±6.5ml/min vs. 59.2±9.3ml/min, P<0.0001).


CONCLUSIONS
Beginning OPCAB early after CAG did affect postoperative renal function and increased the incidence of AKI.
Department of Thoracic Cardiovascular Surgery, Tongji Hospital, Tongji University, Shanghai, PR China.
Qiang
Q
Ji
Yunqing
Y
Mei
Xisheng
X
Wang
Jing
J
Feng
Dewei
D
Wusha
Jianzhi
J
Cai
Yongxin
Y
Zhou
D058186:Acute Kidney Injury / Q000000981:diagnostic imaging / Q000503:physiopathology; D000368:Aged; D017023:Coronary Angiography; D047549:Coronary Artery Bypass, Off-Pump / Q000009:adverse effects*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D011184:Postoperative Period; D012189:Retrospective Studies; D013997:Time Factors