[Comparative study on chemical quality of main species of epimedium].
This study was to comprehensively evaluate the chemical quality of main species of epimedium planted in China. The contents of 5 marker compounds, epimedin A, epimedin B, epimedin C, icariin and baohuoside I, as well as total flavonoids of 22 samples of 8 officinal species of Epimedium were determined by HPLC and UV, separately. Some physical and chemical tests (H2O, total ash, acid-insoluble ash and EtOH extract) were also carried out to investigate their chemical qualities. There were significant differences in types and contents of prenyl-flavonoid glycosides such as epimedin A, epimedin B, epimedin C, icariin and baohuoside I in different species, meanwhile, the physical and chemical parameters results also showed that there were obvious differences in chemical quality among different species of epimedium herb. The results provide theoretical and experimental basis for the establishment of comprehensive quality assessment system of epimedium in China.
School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Sun
S
Han
Yuan-Yuan
YY
Xie
Yi-Ming
YM
Wang
Qiong-Lin
QL
Liang
Guo-An
GA
Luo
D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification; D034181:Epimedium / Q000737:chemistry* / Q000145:classification; D005419:Flavonoids / Q000032:analysis*; D010946:Plants, Medicinal / Q000737:chemistry; D011786:Quality Control; D013045:Species Specificity; D013056:Spectrophotometry, Ultraviolet / Q000379:methods
D004365:Drugs, Chinese Herbal; D005419:Flavonoids; C529106:epimedin A; C106053:epimedin B; C106054:epimedin C; C060988:baohuoside I; C056599:icariin