In vitro bioactivity of essential oils and methanol extracts of Salvia reuterana from Iran.
The chemical composition of the essential oils, antioxidant activity (DPPH and beta-carotene/linoleic acid assays) and total phenolic content (Foline-Ciocalteu) of the flowers and leaves of Salvia reuterana were determined. Essential oils extracted from the flowers and leaves by hydrodistillation were analyzed by GC and GC/MS. Forty-four constituents, representing 99.7-99.9% of the oils, were identified. The major components were germacrene D, benzoic acid hexyl ester, bicyclogermacrene, beta-gurjunene and ishwarene, constituting 33.7-31.9% of the oils. The highest radical-scavenging activity (DPPH test) was shown by the methanol extract of the flowers (IC50 = 77.6 microg/mL). In the beta-carotene/linoleic acid assay, the methanol extract of the leaves showed the highest inhibition (40.3%) which was only slightly lower than that shown by BHT (82.9%). The total phenolic contents of the methanol extracts of the flowers and leaves as gallic acid equivalents were 81.4 and 88.3 microg/mg, respectively. The plant also showed good antimicrobial activity against three strains of tested microorganisms.
Essential Oils Research Institute, University of Kashan, Post code: 87317-51167, Kashan, Islamic Republic of Iran. safaei@kashanu.ac.ir
Javad Safaei
JS
Ghomi
Reihaneh
R
Masoomi
Fereshteh Jookar
FJ
Kashi
Hossein
H
Batooli
D000890:Anti-Infective Agents / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D007492:Iran; D000432:Methanol / Q000737:chemistry; D009822:Oils, Volatile / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D027544:Salvia / Q000737:chemistry*
D000890:Anti-Infective Agents; D000975:Antioxidants; D009822:Oils, Volatile; D010936:Plant Extracts; D000432:Methanol