Solitary plasmacytoma of the bone involving young individuals, is there a role for preceding trauma?
Solitary plasmacytoma of the bone (SPB) is a rare plasma cell neoplasm that usually presents as a lytic lesion mainly localized within the axial skeleton. The occurrence of SPB in young individuals is exceedingly rare but has been sporadically reported before. We report a case of SPB involving a 21 year-old male with a prior history of trauma at the same site. We also reviewed all previous cases of SPB in young individuals that were accessible to us to investigate the incidence of prior trauma in such cases and to investigate a potential role that trauma may play in the pathogenesis of such lesions.
Department of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA, USA.
Whitney
W
Pasch
Xiaohui
X
Zhao
Sherif A
SA
Rezk
D014408:Biomarkers, Tumor / Q000378:metabolism; D001859:Bone Neoplasms / Q000209:etiology* / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007085:Ilium / Q000473:pathology; D007070:Immunoglobulin A / Q000378:metabolism; D008297:Male; D010014:Osteolysis / Q000150:complications / Q000473:pathology; D010954:Plasmacytoma / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D014947:Wounds and Injuries / Q000150:complications / Q000473:pathology*; D055815:Young Adult
D014408:Biomarkers, Tumor; D007070:Immunoglobulin A