Preparation and antibacterial activities of hollow silica-Ag spheres.
Hollow silica spheres with round mesoporous shells were synthesized by core-shell template method, using monodispersed cationic polystyrene particles as core, and TEOS (tetraethoxysilane) as the silica source to form shell. After calcination at 550°C, uniform spheres with a thin shell of silica and hollow interior structures. Transmission electron microscopy results showed that the size of the spheres is about 700 nm in diameter with narrow distribution. In addition, the spheres have a high surface area of 183 m(2)/g. The spheres were subsequently used as silver-loading substrates and the silver loaded spheres were tested in antimicrobial study against gram negative bacteria Eschrichia coli in vitro. The hollow silica-Ag spheres proved significantly higher antibacterial efficacy against E. coli as compared to that of the common silica-Ag particles.
School of Food & Biological Engineering, Jiangsu University, Zhenjiang 212013, PR China.
Lin
L
Lin
Haifang
H
Zhang
Haiying
H
Cui
Mingqiang
M
Xu
Shunsheng
S
Cao
Guanghong
G
Zheng
Mingdong
M
Dong
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D002412:Cations / Q000737:chemistry; D004339:Drug Compounding; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles; D012821:Silanes / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry*; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D002412:Cations; D012821:Silanes; D012834:Silver; C040733:tetraethoxysilane; D012822:Silicon Dioxide