Extraskeletal effects of vitamin D: potential impact on WV disease morbidity and mortality.
Vitamin D is an essential nutrient and a secosteroid hormone that regulates many physiologic processes beyond calcium and bone homeostasis. These "extraskeletal" effects are impacted by the circulating levels of the storage form of vitamin D, 25-hydroxyvitamin D3. Levels of vitamin D can be detected after completing a simple 25(OH)D blood test. Vitamin D deficiency (< 30 ng/mL) is associated with a higher risk of many chronic diseases including, but not limited to, fourteen types of cancers, type 1 and 2 diabetes mellitus, obesity, cardiovascular disease, hypertension, stroke, and asthma. This article explores the association between vitamin D deficiency and the burden of chronic diseases in West Virginia.
Geriatric Fracture Program, Joan C Edwards School of Medicine, Marshall University, Huntington, USA.
Franklin D
FD
Shuler
Dana
D
Lycans
Elias
E
Salloum
D001249:Asthma / Q000209:etiology; D002318:Cardiovascular Diseases / Q000209:etiology; D003920:Diabetes Mellitus / Q000209:etiology; D006801:Humans; D024821:Metabolic Syndrome / Q000209:etiology; D009369:Neoplasms / Q000209:etiology; D014807:Vitamin D / Q000097:blood; D014808:Vitamin D Deficiency / Q000150:complications* / Q000175:diagnosis
D014807:Vitamin D