Chirality and homochirality of lipids is necessary to form LD-supramolecular structures of cell-cell communications.
The processes of cell-cell commutations via anisometric supramolecular structures (strings) in vitro and in physicochemical models of lipids (trifluoroacetylated amino alcohols) were studied. It was shown that biological commutation through strings is more efficient than the diffusion mechanism of transfer of bioactive molecules at distances typical of populations. Strings kinetics was constructed and the signal turnover rate in these systems was evaluated. It was demonstrated that the condition of chirality of lipids forming the cell biomembrane stems from experimentally observed cell commutation through anisometric supramolecular structures.
N. N. Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow, Russia. s.stovbun@chph.ras.ru
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D000605:Amino Alcohols / Q000737:chemistry; D002450:Cell Communication; D021961:Cell Membrane Structures / Q000737:chemistry / Q000648:ultrastructure; D007536:Isomerism; D008055:Lipids / Q000737:chemistry; D046911:Macromolecular Substances / Q000737:chemistry* / Q000648:ultrastructure; D008958:Models, Molecular; D044366:Transition Temperature
D000605:Amino Alcohols; D008055:Lipids; D046911:Macromolecular Substances