Thyrotoxic periodic paralysis associated with transient thyrotoxicosis due to painless thyroiditis.
Thyrotoxic periodic paralysis (TPP) is a rare manifestation of hyperthyroidism characterized by muscle weakness and hypokalemia. All ethnicities can be affected, but TPP typically presents in men of Asian descent. The most common cause of TPP in thyrotoxicosis is Graves' disease. However, TPP can occur with any form of thyrotoxicosis. Up to our knowledge, very few cases ever reported the relationship between TPP and painless thyroiditis. We herein report a 25-yr-old Korean man who suffered from flaccid paralysis of the lower extremities and numbness of hands. The patient was subsequently diagnosed as having TPP associated with transient thyrotoxicosis due to painless thyroiditis. The paralytic attack did not recur after improving the thyroid function. Therefore, it is necessary that early diagnosis of TPP due to transient thyrotoxicosis is made to administer definite treatment and prevent recurrent paralysis.
Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea.
Sang Bo
SB
Oh
Jinhee
J
Ahn
Min Young
MY
Oh
Bo Gwang
BG
Choi
Ji Hyun
JH
Kang
Yun Kyung
YK
Jeon
Sang Soo
SS
Kim
Bo Hyun
BH
Kim
Yong Ki
YK
Kim
In Joo
IJ
Kim
D000284:Administration, Oral; D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D006801:Humans; D020514:Hypokalemic Periodic Paralysis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D008297:Male; D015609:Organotechnetium Compounds / Q000737:chemistry; D011189:Potassium Chloride / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use; D011859:Radiography; D019275:Radiopharmaceuticals; D013966:Thyroiditis / Q000150:complications* / Q000000981:diagnostic imaging; D013971:Thyrotoxicosis / Q000175:diagnosis* / Q000209:etiology; D014463:Ultrasonography
D000889:Anti-Arrhythmia Agents; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D011189:Potassium Chloride; D011433:Propranolol