Role of peptides in epigenetic regulation of gene activities in ontogeny.
The authors develop a new concept most fully reflecting the evolutional and biological role of peptides in the organism. Wide spectrum of peptide effects realized through regulation of the expression of certain genes is aimed at the maintenance of homeostasis, inhibition of the genetic aging program realization, and lifespan prolongation.
I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia.
V Kh
VKh
Khavinson
V V
VV
Malinin
B F
BF
Vanyushin
D000375:Aging / Q000235:genetics*; D001665:Binding Sites; D005075:Biological Evolution; D004247:DNA / Q000235:genetics* / Q000378:metabolism; D044127:Epigenesis, Genetic; D057890:Epigenomics; D006706:Homeostasis / Q000235:genetics; D006801:Humans; D009842:Oligopeptides / Q000235:genetics* / Q000378:metabolism; D011485:Protein Binding
D009842:Oligopeptides; D004247:DNA