Sclerotic fibroma (storiform collagenoma)-like stroma in a fibroadenoma of axillary accessory breast tissue.
Accessory breast tissue is a subcutaneous remnant persisting after normal embryological development of the breast. It occurs most frequently in the axilla. Fibroadenomas in axillary breast tissue are rare. We report the case of a 29-year-old female patient who presented a fibroadenoma arising in the accessory breast tissue of the right axillary fossa. The neoplasm showed foci of sclerotic fibroma-like stroma. The patient had no signs of Cowden's syndrome. To the best of our knowledge, a lesion of this kind has not been previously reported. This stromal change suggests an uncommon involutional phase of the fibroadenoma with production of sclerotic and hypocellular collagen. The lesion should be differentiated from extraneural perineuroma, from the changes in fibroadenomas in Cowden's syndrome, from sclerosing lobular hyperplasia (fibroadenomatoid mastopathy) and from pseudoangiomatous stromal hyperplasia.
Anatomical Pathology Department, Marqués de Valdecilla, University Hospital, Medical Faculty, University of Cantabria and IFIMAV, Santander, Spain. apavbj@humv.es
José Fernando
JF
Val-Bernal
María Carmen
MC
González-Vela
Mauricio
M
De Grado
María Francisca
MF
Garijo
D000328:Adult; D000798:Angiomatosis / Q000175:diagnosis; D001365:Axilla / Q000473:pathology; D001940:Breast; D001941:Breast Diseases / Q000175:diagnosis; D001943:Breast Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D002828:Choristoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D003094:Collagen / Q000378:metabolism; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005348:Fibrocystic Breast Disease / Q000175:diagnosis; D005350:Fibroma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006223:Hamartoma Syndrome, Multiple / Q000175:diagnosis; D006801:Humans; D006965:Hyperplasia / Q000175:diagnosis; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis; D012598:Sclerosis; D017154:Stromal Cells / Q000378:metabolism / Q000473:pathology
D003094:Collagen