Genetic characterization of Bhanja virus and Palma virus, two tick-borne phleboviruses.
The genomes of Bhanja virus (BHAV) and Palma virus (PALV) two tick-borne viruses hitherto grouped into the Bhanja virus antigenic complex of the Bunyaviridae were determined by pyrosequencing. Phylogenetic analysis groups all three segments of BHAV and PALV into a distinct clade of tick-borne phleboviruses together with the newly described severe fever with thrombocytopenia syndrome virus and Uukuniemi virus. The terminal signature sequences which are signatures for taxonomic grouping and important for virus replication and RNA transcription show marked differences in the L- and S-segments.
Department of Virology, University Medical Center Goettingen, Kreuzbergring 57, 37075 Göttingen, Germany.
Meik
M
Dilcher
Maria João
MJ
Alves
Dora
D
Finkeisen
Frank
F
Hufert
Manfred
M
Weidmann
D016000:Cluster Analysis; D016679:Genome, Viral; D008969:Molecular Sequence Data; D016856:Phlebovirus / Q000235:genetics*; D010802:Phylogeny; D011174:Portugal; D012367:RNA, Viral / Q000235:genetics*; D017422:Sequence Analysis, DNA
D012367:RNA, Viral