Self-collection of specimens for nucleic acid-based diagnosis of pharyngeal, cervicovaginal, urethral, and rectal Neisseria gonorrhoeae and Chlamydia trachomatis infections.
Commercially available nucleic acid amplification tests (NAATs) for Neisseria gonorrhoeae and Chlamydia trachomatis detection allow for self-collection including home-based collection from multiple anatomic sites such as the urethra, cervicovagina, rectum, and pharynx. Verification studies need to be done prior to processing pharyngeal and rectal specimens. We review specimen collection and test characteristics of NAATs at different anatomical sites.
San Mateo County Health System, San Mateo, CA, USA. vlevy@stanford.edu
Vivian
V
Levy
Craig S
CS
Blackmore
Jeffrey D
JD
Klausner
D002584:Cervix Uteri / Q000382:microbiology; D002690:Chlamydia Infections / Q000175:diagnosis* / Q000235:genetics; D002692:Chlamydia trachomatis / Q000235:genetics / Q000472:pathogenicity; D004269:DNA, Bacterial / Q000235:genetics*; D005260:Female; D006069:Gonorrhea / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D009344:Neisseria gonorrhoeae / Q000235:genetics / Q000472:pathogenicity; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D010614:Pharynx / Q000382:microbiology; D012329:RNA, Bacterial / Q000235:genetics*; D012007:Rectum / Q000382:microbiology; D013048:Specimen Handling / Q000295:instrumentation / Q000379:methods*; D014521:Urethra / Q000382:microbiology; D014621:Vagina / Q000382:microbiology
D004269:DNA, Bacterial; D012329:RNA, Bacterial