Direct electrochemical reduction of graphene oxide and its application to determination of L-tryptophan and L-tyrosine.
Directly electrochemically reduced graphene oxide (ERGO) was obtained by potentiostatic reduction of exfoliated graphene oxide sheets on a glassy carbon electrode (GCE). The ERGO-modified electrode (ERGO/GCE) displayed greatly improved voltammetric response to the amino acids l-tryptophane (Trp) and l-tyrosine (Tyr) compared with the chemically reduced graphene oxide (CRGO) modified electrode. The ERGO/GCE separated the voltammetric responses of ascorbic acid (AA) and uric acid (UA) from that of Trp and Tyr. It eliminated the interference from AA and UA. The electrode showed good reproducibility and was used to determine Trp and Tyr with linear ranges of 0.2-40.0 μmol L(-1)and 0.5-80.0 μmol L(-1), detection limits of 0.1 μmol L(-1) and 0.2 μmol L(-1), respectively.
School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, PR China. keqindeng@yahoo.com.cn
Ke-Qin
KQ
Deng
Jian-hong
JH
Zhou
Xiao-Fang
XF
Li
D001205:Ascorbic Acid / Q000737:chemistry; D002021:Buffers; D004563:Electrochemistry; D004566:Electrodes; D006108:Graphite / Q000737:chemistry*; D007202:Indicators and Reagents; D015203:Reproducibility of Results; D013059:Spectrum Analysis, Raman; D014364:Tryptophan / Q000032:analysis*; D014443:Tyrosine / Q000032:analysis*; D014527:Uric Acid / Q000737:chemistry
D002021:Buffers; D007202:Indicators and Reagents; D014527:Uric Acid; D014443:Tyrosine; D006108:Graphite; D014364:Tryptophan; D001205:Ascorbic Acid