Effect of nanosilver on blood parameters in chickens having aflatoxicosis.
This experiment is designed to investigate the positive effects of commercial nanosilver compound on blood parameters in experimental aflatoxicosis in broiler chickens. For this, 270 one-day-old broiler chickens were randomly divided into six treatment groups with three replicates. The experimental groups were group A: chickens fed with basal diet; group B: chickens fed with 3 ppm productive aflatoxin in basal diet; groups of C, D, E and F received Mycoad (2.5 g/kg diet), Mycoad (2.5 g/kg diet) + productive aflatoxin (3 ppm), Nanocid (2500 ppm), and Nanocid (2500 ppm) + productive aflatoxin (3 ppm) in basal diet, respectively. Results revealed that some of the blood parameters such as mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration lymphocytes, neutrophils, basophils, monocytes, and eosinophils percentage were not affected in this experiment; whereas, hemoglobin percentage and white blood cell (WBC) count in all the groups fed with 3 ppm aflatoxin except nanocid + aflatoxin decreased significantly (p < 0.05). There are no significant differences between the groups that received nanocid + aflatoxin and mycoad + aflatoxin in hemoglobin percentage and WBC count parameters. The red blood cell count and hematocrit in chickens received aflatoxin were significantly lower than other groups (p < 0.05). Therefore, this study suggests that nanocid similar as mycoad can be useful in reducing the adverse effects of aflatoxin on blood parameters in chickens affected with aflatoxicosis.
1Department of Poultry Diseases, Faculty of Veterinary Medicine, Shahrekord Branch, Islamic Azad University, Shahrekord, Iran.
Majid
M
Gholami-Ahangaran
Noosha
N
Zia-Jahromi
D000348:Aflatoxins / Q000008:administration & dosage / Q000633:toxicity*; D000821:Animal Feed / Q000032:analysis; D000818:Animals; D001491:Basophils / Q000187:drug effects; D002645:Chickens; D004305:Dose-Response Relationship, Drug; D004804:Eosinophils / Q000187:drug effects; D004906:Erythrocyte Count; D004909:Erythrocyte Indices / Q000187:drug effects / Q000502:physiology; D005506:Food Contamination / Q000517:prevention & control*; D007958:Leukocyte Count; D008214:Lymphocytes / Q000187:drug effects; D053768:Metal Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry; D009000:Monocytes / Q000187:drug effects; D009504:Neutrophils / Q000187:drug effects; D011201:Poultry Diseases / Q000188:drug therapy / Q000382:microbiology*; D012834:Silver / Q000008:administration & dosage* / Q000737:chemistry
D000348:Aflatoxins; D012834:Silver