Exophytic glioblastoma arising from the cerebellum: case report and critical review of the literature.
Exophytic glioblastoma arising from the cerebellar tonsil is an extremely rare variant within the possible anatomical presentations of the glioblastoma multiforme (GBM). We report the case of a 55-year-old woman who presented with a tumor located at the cranio-cervical junction with compression of the medulla oblongata and consecutive hydrocephalus. Due to the radiological presentation, the first tentative diagnosis was a meningioma. The tumor was microsurgically removed. Histopathological examination of the tumor revealed a GBM WHO IV. The patient underwent a postoperative percutaneous radiotherapy and concomitant chemotherapy with temozolomide. GBM should be also considered in the differential diagnosis of cerebellar tumors.
Department of Neurosurgery, University of Wuerzburg, Wuerzburg, Bavaria, Germany. linsenmann.t@nch.uni-wuerzburg.de
Thomas
T
Linsenmann
Camelia Maria
CM
Monoranu
Thomas
T
Westermaier
Csanad
C
Varallyay
Ralf-Ingo
RI
Ernestus
Giles Hamilton
GH
Vince
D002528:Cerebellar Neoplasms / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D059248:Chemoradiotherapy; D003399:Craniotomy; D005260:Female; D005909:Glioblastoma / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008526:Medulla Oblongata / Q000473:pathology; D008875:Middle Aged; D016612:Paraffin Embedding; D016707:Tissue Fixation; D016896:Treatment Outcome