Xenotropic murine leukemia virus-related virus proviral DNA not detected in blood samples donated in Japan.
The xenotropic murine leukemia virus-related virus (XMRV) was first described as a  novel human gammaretrovirus in prostate tumor tissues and was reported to be found in blood, suggesting  the possibility of XMRV transmission via blood transfusion. The gag and env regions of the XMRV  proviral DNA that were detected 1,030 blood samples collected from the greater Tokyo area were examined  by real-time PCR analysis. However, XMRV infection was not found in the samples; this suggested that  the risk of XMRV transmission via transfusion is very low in Japan.
Japanese Red Cross Society Blood Service Headquarters, 2-1-67 Tatsumi, Koto-ku, Tokyo, Japan. c-matsumoto＠jrc.or.jp
Chieko
C
Matsumoto
Masashi
M
Igarashi
Rika A
RA
Furuta
Shigeharu
S
Uchida
Masahiro
M
Satake
Kenji
K
Tadokoro
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001782:Blood Donors; D004279:DNA, Viral / Q000097:blood*; D005260:Female; D015752:Genes, env; D015750:Genes, gag; D015894:Genome, Human; D006801:Humans; D008297:Male; D051379:Mice; D008875:Middle Aged; D011533:Proviruses / Q000235:genetics*; D016662:Virus Integration; D058008:Xenotropic murine leukemia virus-related virus / Q000235:genetics*; D055815:Young Adult
D004279:DNA, Viral