Antioxidant, hemolytic and cytotoxic activities of Senecio species used in traditional medicine of northwestern Argentina.
Senecio nutans Sch. Bip., S. viridis var. viridis Phill. and S. spegazzinii Cabrera are native species used in traditional medicine of northwestern Argentina. The total phenolics, flavonoids and caffeoylquinic acids contents, as well as radical scavenging, antioxidant, hemolytic and cytotoxic activities of aqueous extracts (infusion and decoction) of all three species were determined. S. nutans was the most active. The extracts did not show antibacterial activity. Alkaloids were not detected in any of the aqueous extracts of the three studied species.
lNQUINOA-CONICET, Instituto de Química Orgánica, Facultad de Bioquímica Quimica y Farmacia, Universidad Nacional de Tucumán, Ayacucho 471, S. M. de Tucumán, Argentina.
Emilio
E
Lizarraga
Felipe
F
Castro
Francisco
F
Fernández
Marina P
MP
de Lampasona
César A N
CA
Catalán
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001118:Argentina; D001156:Artemia; D005419:Flavonoids / Q000032:analysis; D006461:Hemolysis / Q000187:drug effects*; D008519:Medicine, Traditional; D010936:Plant Extracts / Q000032:analysis / Q000494:pharmacology* / Q000633:toxicity; D012674:Senecio / Q000737:chemistry*
D000975:Antioxidants; D005419:Flavonoids; D010936:Plant Extracts