Unusual association of Arnold-Chiari malformation and vitamin B12 deficiency.
Arnold-Chiari malformations are a group of congenital or acquired defects associated with the displacement of cerebellar tonsils into the spinal canal. First described by Chiari (1891), this has various grades of severity and involves various parts of neuraxis, for example, cerebellum and its outputs, neuro-otological system, lower cranial nerves, spinal sensory and motor pathways. The symptomatology of Arnold-Chiari malformations may mimic multiple sclerosis, primary headache syndromes, spinal tumours and benign intracranial hypertension. We highlighted a case of Chiari type I malformation, who presented with posterolateral ataxia associated with significant vitamin B(12) deficiency. The patient was supplemented with vitamin B(12) injections and showed remarkable improvement at follow-up after 3&emsp14;months.
Department of Neurology, Chhatrapati Shahuji Maharaj Medical University, Lucknow, Uttar Pradesh, India. drrajeshverma32@yahoo.com
Rajesh
R
Verma
Heramba Narayan
HN
Praharaj
D001139:Arnold-Chiari Malformation / Q000150:complications* / Q000175:diagnosis; D002531:Cerebellum / Q000002:abnormalities / Q000473:pathology; D003937:Diagnosis, Differential; D005539:Foramen Magnum / Q000473:pathology; D006801:Humans; D007273:Injections, Intramuscular; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014805:Vitamin B 12 / Q000008:administration & dosage*; D014806:Vitamin B 12 Deficiency / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D014803:Vitamin B Complex / Q000008:administration & dosage
D014803:Vitamin B Complex; D014805:Vitamin B 12