Management of bullous keratopathy-related ulcer with autologous serum.
OBJECTIVE
The aim of this study was to report the use of autologous serum eyedrops (ASEs) for resolution of a corneal ulcer secondary to bullous keratopathy.


METHODS
This is a case report.


RESULTS
A 66-year-old patient presented with an infected ulcer and hypopyon while using a bandage contact lens for bullous keratopathy. Staphylococcus warneri infection was treated with systemic and topical antibiotics, and ASEs were subsequently administered to enhance reepithelialization and to avoid the need for a bandage contact lens. The ASE treatment led to closure of the epithelium layer within 3 weeks, and it was subsequently tapered over the next 3 months. The clinical picture remained stable subjectively and objectively during the 7 months of follow-up.


CONCLUSIONS
To the best of our knowledge, this is the first report of successful use of ASEs in treating and preventing recurrence of ulcers in the context of bullous keratopathy.
IInd Department of Ophthalmology, Aristotle University of Thessaloniki, Thessaloniki, Greece. mataftsi@doctors.org.uk
Asimina
A
Mataftsi
Areti
A
Bourtoulamaiou
Konstantinos
K
Anastasilakis
Nikolaos G
NG
Ziakas
Stavros A
SA
Dimitrakos
D000368:Aged; D003316:Corneal Diseases / Q000150:complications / Q000628:therapy; D003320:Corneal Ulcer / Q000209:etiology / Q000628:therapy*; D015818:Eye Infections, Bacterial / Q000150:complications; D005260:Female; D006801:Humans; D009883:Ophthalmic Solutions / Q000627:therapeutic use*; D044967:Serum; D013203:Staphylococcal Infections / Q000150:complications; D014182:Transplantation, Autologous; D016896:Treatment Outcome
D009883:Ophthalmic Solutions