[The changes of peripheral blood lymphocyte subsets in patients with acute hydrogen chloride gas poisoning].
OBJECTIVE
To explore the changes of peripheral blood lymphocyte subsets in patients with acute hydrogen chloride gas poisoning.


METHODS
When the patients were admitted or on the secondary day, the percentages of total T-cell lymphocyte subsets (CD(3)(+)CD(19)(-)), CD(4)(+)T cells (CD(3)(+)CD(4)(+)), CD(8)(+)T cells (CD(3)(+)CD(8)(+)), B cells (CD(3)(-)CD(19)(+)) and NK cells (CD(3)(-)CD(16)(+)CD(56)(+)), and the ration of CD(4)(+)/CD(8)(+) in 37 cases with acute hydrogen chloride gas poisoning and 49 healthy controls were detected with flow cytometer.


RESULTS
The total T-cell percentage and total CD(4)(+)T cell percentage in 37 cases were significantly lower than those in 47 controls (P < 0.05). The percentages of NK cells and B lymphocytes in 37 cases significantly increased, as compared with controls (P < 0.05). The ration of CD(4)(+)/CD(8)(+) in 37 cases significantly decreased, as compared with controls (P < 0.05).


CONCLUSIONS
The lymphocyte subsets in the patients with acute hydrogen chloride gas poisoning changed, which could influence the immune function of patients.
Xinchang People's Hospital, Zhejiang 312500, China.
Ya-li
YL
Lü
Chuan-jun
CJ
Chen
Bi-xia
BX
Liang
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D005260:Female; D005739:Gas Poisoning / Q000097:blood*; D006801:Humans; D006851:Hydrochloric Acid / Q000506:poisoning*; D018655:Lymphocyte Count; D016131:Lymphocyte Subsets / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D055815:Young Adult
D006851:Hydrochloric Acid