Changes in the subarachnoid space precede ventriculomegaly in idiopathic normal pressure hydrocephalus (iNPH).
We report on an 80-year-old woman who had shunt-responsive idiopathic normal pressure hydrocephalus (iNPH). Her brain MRI showed an initial change in the subarachnoid space (a disproportional narrowing of the subarachnoid space at the cerebral high convexities) at the age of 70 years, followed by enlargement of the ventricles (Evans index: 0.31) at the age of 78. The observation suggests that changes in the subarachnoid space may precede ventricular enlargement in iNPH.
Department of Neurology, Hematology, Metabolism, Endocrinology, and Diabetology, Faculty of Medicine, Yamagata University, Japan. chi-iseki@hyper.ocn.ne.jp
Chifumi
C
Iseki
Yoshimi
Y
Takahashi
Manabu
M
Wada
Shigeki
S
Arawaka
Toru
T
Kawanami
Takeo
T
Kato
D000368:Aged; D000369:Aged, 80 and over; D002552:Cerebral Ventricles / Q000473:pathology*; D002557:Cerebrospinal Fluid Shunts; D005260:Female; D006801:Humans; D006850:Hydrocephalus, Normal Pressure / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D013346:Subarachnoid Space / Q000473:pathology*; D013997:Time Factors