Non-classical congenital adrenal hyperplasia in association with porphyria cutanea tarda: co-incidence or trigger?
We present an interesting case of porphria cutanea tarda with hereditary haemochromatosis and non-classical congenital adrenal hyperplasia in a postmenopausal woman. This unusual combination of conditions does not appear to be reported in the literature. The exact mechanism causing porphyria in this patient is not clear. We consider the possibility that in addition to iron accumulation and excess alcohol, altered steroid milieu may have been a possible trigger for the development of bullous lesions in this patient.
Department of Chemical Pathology, Salford Royal NHS Foundation Trust, Salford M6 8HD, UK. mamadeep@gmail.com
Mamatha
M
Ramaswamy
Russell
R
Ead
Helen
H
Buckler
John
J
Houghton
Mary Felicity
MF
Stewart
D000312:Adrenal Hyperplasia, Congenital / Q000150:complications* / Q000473:pathology; D000728:Androgens / Q000097:blood; D005260:Female; D006801:Humans; D008875:Middle Aged; D017119:Porphyria Cutanea Tarda / Q000150:complications* / Q000473:pathology; D011166:Porphyrins / Q000097:blood
D000728:Androgens; D011166:Porphyrins