Infection and autoimmune disease.
Most infectious agents, such as viruses, bacteria and parasites, can trigger autoimmunity via different mechanisms. The development of an autoimmune disorder after infection tends to occur in genetically susceptible individuals. Some parameters, such as genetic predisposition, feature of the infectious agent and sometimes protective effect of the infections, have a significant role in this process. These parameters and various pathogens that could lead to enhancement or exacerbation of autoimmune disease were examined in this review. Recent studies were reviewed from a microbiological perspective.
Microbiology and Clinical Microbiology Department, Ataturk Training and Research Hospital, Izmir, Turkey. agsener@gmail.com
Asli Gamze
AG
Sener
Ilhan
I
Afsar
D000818:Animals; D001327:Autoimmune Diseases / Q000235:genetics / Q000276:immunology / Q000382:microbiology* / Q000821:virology*; D020022:Genetic Predisposition to Disease; D006801:Humans; D007239:Infections / Q000150:complications* / Q000235:genetics / Q000276:immunology