New tricks for metastasis-associated macrophages.
Recent studies on breast cancer lung metastasis have identified a new mechanism of tumor cell survival via signaling provided by metastasis-associated macrophages. Targeting these specialized host immune cells and their specific signals provides an attractive and potential therapeutic approach for treating the disease.
Bin-Zhi
BZ
Qian
Jeffrey W
JW
Pollard
D001943:Breast Neoplasms / Q000276:immunology / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D008264:Macrophages / Q000276:immunology / Q000378:metabolism / Q000473:pathology*; D009362:Neoplasm Metastasis; D015398:Signal Transduction