Highly enantioselective Henry reactions of aromatic aldehydes catalyzed by an amino alcohol-copper(II) complex.
Amino alcohol-Cu(II)  catalyst: Highly enantioselective Henry reactions between aromatic aldehydes and nitromethane have been developed. The reactions were catalyzed by an easily available and operationally simple amino alcohol-copper(II) catalyst. In total, 38 substrates were tested and the R-configured products were obtained in good yields with excellent enantioselectivities.
Department of Chemistry and State Key Laboratory of Physical Chemistry for Solid Surfaces, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian, PR China.
Dan-Dan
DD
Qin
Wen-Han
WH
Lai
Di
D
Hu
Zheng
Z
Chen
An-An
AA
Wu
Yuan-Ping
YP
Ruan
Zhao-Hui
ZH
Zhou
Hong-Bin
HB
Chen