Three new biflavonoids from Chinese dragon's blood, Dracaena cochinchinensis.
Three new biflavonoids, named (2RyS)-3'-methoxy-8-methylsocotrin-4'-ol (1), (2SyR)-3'-methoxy-8-methylsocotrin-4'-ol (2), and (2RyR)-8-methylsocotrin-4'-ol (3), were isolated from Chinese Dragon's blood [Dracaena cochinchinensis (Lour.) S. C. Chen], together with two known ones. The structures of these new biflavonoids were elucidated by a combination of HR-ESI-MS, 1H NMR, 13C NMR, HMQC, and HMBC spectra. The absolute configurations of compounds 1-4 were determined by quantum chemical calculation of the circular dichroism spectrum and comparison with the experimental CD spectrum.
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, PR China.
Jing
J
Guan
Shun-Xing
SX
Guo
D044946:Biflavonoids / Q000737:chemistry / Q000302:isolation & purification*; D031409:Dracaena / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000032:analysis*; D021241:Spectrometry, Mass, Electrospray Ionization
C574046:(2RyR)-8-methylsocotrin-4'-ol; C574047:(2RyS)-3'-methoxy-8-methylsocotrin-4'-ol; C574048:(2SyR)-3'-methoxy-8-methylsocotrin-4'-ol; D044946:Biflavonoids; D010936:Plant Extracts; C525191:dragon's blood