[Chemical constituents from roots of Machilus yaoshansis].
To study chemical constituents contained in ethanol extracts from roots of Machilus yaoshansis. Fifteen compounds were separated from the roots of M. yaoshansis by using various chromatographic techniques. Their structures were identified on the basis of their physicochemical properties and spectral data as twelve lignans(+)-guaiacin (1), kadsuralignan C (2), (+)-isolariciresinol (3), 5'-methoxy-(+)-isolariciresinol (4), (7'S, 8R, 8'R)-lyoniresinol (5), meso-secoisolariciresinol (6), isolariciresinol-9'-O-beta-D-xylopyranoside (7), 5'-methoxy-isolariciresinol-9'-O-beta-D-xylopyranoside (8), lyoniresinol-9'-O-beta-D-xylopyranoside (9), (2R, 3R) -2, 3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-3-methyl-5-(E)-propenylbenzofuran (10), 3, 5'-dimethoxy-4', 7-epoxy-8, 3'-neolignan-4, 9, 9'-triol (11), nectandrin B (12), and three flavanes(+)-catechin (13), (-)-epicatechin (14), and bis-8, 8'-catechinylmethane (15). All of the compounds 1-15 were separated from M. yaoshansis for the first time.
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
Bo
B
Liu
Mingtao
M
Liu
Maoluo
M
Gan
Feng
F
Zhao
Xiuli
X
Wu
Yang
Y
Yu
Zhenggang
Z
Yue
Sheng
S
Lin
Sujuan
S
Wang
Chenggen
C
Zhu
Jiangong
J
Shi
D002072:Butylene Glycols / Q000737:chemistry; D002392:Catechin / Q000737:chemistry; D019770:Lauraceae / Q000737:chemistry*; D017705:Lignans / Q000737:chemistry; D008031:Lignin / Q000737:chemistry; D009284:Naphthols / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry*
D002072:Butylene Glycols; D017705:Lignans; D009284:Naphthols; C524653:nectandrin-B; C060284:isolariciresinol; D002392:Catechin; D008031:Lignin; C060283:secoisolariciresinol