Synthesis and functionalization of CdSe/ZnS QDs using the successive ion layer adsorption reaction and mercaptopropionic acid phase transfer methods.
Detailed protocols for the preparation of CdSe nanocrystals coated with a multishell structure of ZnS and their surface modification based on the successive ion layer adsorption and reaction method are described. The first phase of the synthesis produces a hydrophobic surface consisting of a TOPO/HDA ligand mixture. This is followed by a surface modification of the quantum dots (QDs) with 3-mercaptopropionic acid by the phase transfer method. The modified QDs become soluble in aqueous systems such as water or buffers for further biological applications.
Organic Synthesis Laboratory, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal. sofmig@itqb.unl.pt
Ana Sofia
AS
Miguel
Christopher
C
Maycock
Abel
A
Oliva
D015097:3-Mercaptopropionic Acid / Q000737:chemistry*; D000327:Adsorption; D019187:Cadmium Compounds / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D007477:Ions / Q000737:chemistry*; D044367:Phase Transition; D045663:Quantum Dots; D018036:Selenium Compounds / Q000737:chemistry*; D012995:Solubility; D013440:Sulfides / Q000737:chemistry*; D014867:Water / Q000737:chemistry; D017967:Zinc Compounds / Q000737:chemistry*
D019187:Cadmium Compounds; D007477:Ions; D018036:Selenium Compounds; D013440:Sulfides; D017967:Zinc Compounds; D014867:Water; C058667:cadmium selenide; D015097:3-Mercaptopropionic Acid; C031238:zinc sulfide