Electrospray ionization mass spectrometric analysis of highly reactive glycosyl halides.
Highly reactive glycosyl chlorides and bromides have been analysed by a routine mass spectrometric method using electrospray ionization and lithium salt adduct-forming agents in anhydrous acetonitrile solution, providing salient lithiated molecular ions [M+Li]⁺, [2M+Li]⁺ etc. The role of other adduct-forming salts has also been evaluated. The lithium salt method is useful for accurate mass determination of these highly sensitive compounds.
Department of Medicinal Chemistry, Faculty of Medicine, University of Szeged, Dóm Tér 8, H-6720 Szeged, Hungary.
Attila
A
Bokros
Annamária
A
Bánfi
Zoltán
Z
Kupihár
Zoltán
Z
Kele
Tünde Zita
TZ
Illyés
János
J
Szolomájer
Lajos
L
Kovács
D002138:Calibration; D006027:Glycosides / Q000737:chemistry*; D006219:Halogens / Q000737:chemistry*; D008970:Molecular Weight; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*
D006027:Glycosides; D006219:Halogens