Preliminary study of a novel in-office bleaching therapy modified with a casein phosphopeptide-amorphous calcium phosphate.
Although in-office bleaching has been proven successful for bleaching teeth, controversy exists from morphological alterations in enamel morphology due to mineral loss and tooth sensitivity. This preliminary study aimed to evaluate the efficacy of a novel in-office tooth bleaching technique modified with a casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) paste (MI paste-MI) and its effect on the enamel morphology and tooth sensitivity. Three patients received a 35% hydrogen peroxide (Whiteness HP-HP) dental bleaching system. HP was prepared and applied on the teeth on one of the hemiarches, whilst teeth on the other hemiarch were bleached with a mixture of HP and MI. Tooth color, epoxy resin replicas, and sensitivity levels were evaluated in the upper incisors. The results were analyzed descriptively. Right and left incisors showed similar color change after bleaching. Incisors bleached with the mixture of HP and MI presented unaltered enamel surfaces and lower sensitivity levels. The currently tested tooth bleaching technique did not reduce the gel effectiveness while decreasing hypersensitivity levels and protecting the enamel against surface alterations caused by the high-concentration bleaching peroxide tested. The concomitant use of MI Paste and high-concentration hydrogen peroxide might be a successful method for decreasing tooth sensitivity and limiting changes in the enamel morphology during in-office bleaching.
Department of Dentistry, School of Dentistry, Potiguar University (Laureate International Universities), Natal, Brazil. boniek.castillo@gmail.com
Boniek Castillo Dutra
BC
Borges
Mônica Heloisa Morais
MH
Pinheiro
Diala Aretha De Sousa
DA
Feitosa
Tereza Cristina
TC
Correia
Rodivan
R
Braz
Marcos Antônio Japiassú Resende
MA
Montes
Isauremi Vieira De Assunção
IV
Pinheiro
D002130:Calcium Phosphates / Q000008:administration & dosage* / Q000009:adverse effects; D002364:Caseins / Q000008:administration & dosage* / Q000009:adverse effects; D003116:Color; D003743:Dental Enamel / Q000187:drug effects; D003807:Dentin Sensitivity / Q000139:chemically induced; D006801:Humans; D006861:Hydrogen Peroxide / Q000008:administration & dosage* / Q000009:adverse effects; D010748:Phosphopeptides / Q000008:administration & dosage* / Q000009:adverse effects; D014073:Tooth Bleaching / Q000379:methods*; D058205:Tooth Bleaching Agents / Q000008:administration & dosage* / Q000009:adverse effects; D016896:Treatment Outcome
D002130:Calcium Phosphates; D002364:Caseins; D010748:Phosphopeptides; D058205:Tooth Bleaching Agents; C519480:amorphous calcium phosphate; D006861:Hydrogen Peroxide