Methyl 11-hy-droxy-9-[1-(4-meth-oxy-phen-yl)-4-oxo-3-phen-oxy-azetidin-2-yl]-18-oxo-10-oxa-2-aza-penta-cyclo-[9.7.0.0(1,8).0(2,6).0(12,17)]octa-deca-12(17),13,15-triene-8-carboxyl-ate.
In the title compound, C(34)H(32)N(2)O(8), one of the pyrrolidine rings in the pyrrolizidine ring system adopts a twist conformation, whereas the other ring adopts an envelope conformation (C atom as flap). The five-membered ring in the indene ring system and the fused furan ring also adopt envelope conformations (C and O atoms as flaps, respectively). The β-lactam ring makes dihedral angles of 23.41 (2) and 25.98 (2)°, respectively, with the attached meth-oxy-phenyl and phen-oxy rings. The mol-ecular conformation is stabilized by an intra-molecular O-H⋯N hydrogen bond, generating an S(5) motif. In the crystal, mol-ecules are linked into C(12) chains running along the a axis by C-H⋯O hydrogen bonds. The structure is further consolidated by weak inter-molecular C-H⋯π and π-π inter-actions [centroid-centroid distance = 3.7987 (14) Å].
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Sundaramoorthy
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Rajesh
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Raghunathan
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Velmurugan