Identification of enterocin NKR-5-3C, a novel class IIa bacteriocin produced by a multiple bacteriocin producer, Enterococcus faecium NKR-5-3.
The structure of enterocin NKR-5-3C, an anti-listerial bacteriocin produced by a multiple bacteriocin producer, Enterococcus faecium NKR-5-3, was determined. Enterocin NKR-5-3C is a novel class IIa bacteriocin that possesses an YGNGL motif sequence and two disulfide bridges in its structure. It is encoded on gene ent53C together with an 18-amino-acid-residue double glycine leader peptide.
Department of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University, Fukuoka, Japan.
Kohei
K
Himeno
Koji
K
Fujita
Takeshi
T
Zendo
Pongtep
P
Wilaipun
Naoki
N
Ishibashi
Yoshimitsu
Y
Masuda
Fuminori
F
Yoneyama
Vichien
V
Leelawatcharamas
Jiro
J
Nakayama
Kenji
K
Sonomoto
D020816:Amino Acid Motifs / Q000235:genetics; D000595:Amino Acid Sequence; D001430:Bacteriocins / Q000737:chemistry* / Q000235:genetics / Q000494:pharmacology; D001483:Base Sequence; D004220:Disulfides / Q000737:chemistry; D016984:Enterococcus faecium / Q000235:genetics* / Q000378:metabolism; D005798:Genes, Bacterial; D008087:Listeria / Q000187:drug effects / Q000254:growth & development; D008969:Molecular Sequence Data; D021382:Protein Sorting Signals / Q000235:genetics; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D020539:Sequence Analysis, Protein
D001430:Bacteriocins; D004220:Disulfides; D021382:Protein Sorting Signals