Preference between precoital and daily use of Duet® and BufferGel in Zimbabwe.
Duet® is a microbicide-delivery system and cervical barrier for use daily or precoitally. We conducted a crossover study among 80 Zimbabwean women to explore factors associated with use-regimen preference. Women were assigned in random order to 14 days of precoital and 14 days of daily Duet and BufferGel use. About 51 % of women preferred precoital use, 39 % preferred daily use, and 10 % liked both equally. Overall product adherence during sex was similar for both use-regimens. In multivariable analysis, diaphragm experience was associated with preference for precoital use (AOR 2.80, 95 % CI 1.01-7.76). Reasons for preferring precoital use included use only when needed, cleanliness, and discomfort with daily use. Daily use preference included convenience, discreetness, and being prepared for "sex-on-demand." Different personal and life circumstances may result in varying use-regimen preferences. Methods that can accommodate both coitally-related and daily use may be advantageous by providing more choice to users.
Women's Global Health Imperative, RTI International, 114 Sansome Street, San Francisco, CA 94104, USA. ariane@rti.org
Ariane
A
van der Straten
Elizabeth
E
Montgomery
Sue
S
Mavedzenge
Petina
P
Musara
Helen
H
Cheng
Alix
A
Lutnick
Cynthia
C
Woodsong
D000180:Acrylic Resins / Q000008:administration & dosage* / Q000009:adverse effects; D000293:Adolescent; D000328:Adult; D000890:Anti-Infective Agents / Q000008:administration & dosage* / Q000009:adverse effects; D003075:Coitus; D003274:Contraceptive Devices, Female / Q000009:adverse effects / Q000706:statistics & numerical data*; D018592:Cross-Over Studies; D016503:Drug Delivery Systems / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D010342:Patient Acceptance of Health Care; D057240:Patient Preference / Q000523:psychology / Q000706:statistics & numerical data*; D012747:Sexual Partners; D012959:Socioeconomic Factors; D013997:Time Factors; D014505:Urban Population; D055815:Young Adult; D015030:Zimbabwe
D000180:Acrylic Resins; D000890:Anti-Infective Agents; C420918:BufferGel