[Experience with the use of IRS-19 for the rehabilitation of children after acute respiratory infections].
The purpose of this work was to evaluate the efficacy of the prevention of recurrent respiratory infections with the use of the immunomodulatory respiratory spray (IRS-19). The study involved 60 children at the age from 4 to 7 years allocated to three groups. Group 1 was comprised of 20 children treated by two daily irrigation of nasal sinuses with a seawater solution. Group 2 included 20 children treated by irrigation of nasal sinuses with IRS-19 twice daily during 2 weeks.. Group 3 consisted of 20 children treated by irrigation of nasal sinuses with a saline solution and topical immunostimulator IRS-19 twice daily. It was shown that therapy with IRS-19 resulted in a more than two-fold reduction in the frequency of relapses of the acute respiratory infections as compared with control.
L V
LV
Mukhomedzianova
I V
IV
Andriianova
I A
IA
Kashirtseva
D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000281:Administration, Intranasal; D001419:Bacteria / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D056747:Immunomodulation / Q000187:drug effects*; D008297:Male; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000276:immunology*; D012623:Seawater; D012965:Sodium Chloride / Q000008:administration & dosage*
D000276:Adjuvants, Immunologic; C079233:IRS 19; D012965:Sodium Chloride