Noninvasive approaches to diagnose intrathoracic extramedullary hematopoiesis: 18F-FLT PET/CT and 99mTc-SC SPECT/CT scintigraphy.
Extramedullary hematopoiesis refers to the presence of hematopoietic elements in locations other than the bone marrow medullary space. It occurs as a compensatory mechanism to impaired hematopoiesis resulting from a variety of pathological conditions. Because of the hazards of biopsy of a highly vascular hematopoietic mass, it is desirable to establish the diagnosis noninvasively. We report a case where 18F-fluoro-3'deoxy-L-thymidine PET/CT and 99mTc-SC scintigraphy were used as a noninvasive modality to diagnose extramedullary hematopoiesis.
Bio-Imaging Unit, Tata Memorial Hospital, Parel, Mumbai, India.
Anand
A
Zade
Nilendu
N
Purandare
Venkatesh
V
Rangarajan
Sneha
S
Shah
Archi
A
Agrawal
Jha
J
Ashish
Mukta
M
Kulkarni
D015224:Dideoxynucleosides; D006411:Hematopoiesis, Extramedullary / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D013902:Radiography, Thoracic; D011877:Radionuclide Imaging; D013667:Technetium; D013909:Thorax / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
D015224:Dideoxynucleosides; D013667:Technetium; C002854:alovudine