Mohs micrographic surgery for the treatment of melanoma.
For melanoma treatment, the primary goal is complete removal with histologically negative margins. Mohs micrographic surgery (MMS) has been extensively used and studied for the treatment of nonmelanoma skin cancer, particularly at sites where tissue conservation is vital. The use of MMS for melanoma treatment has yet to become widely accepted owing to difficulties in histologic interpretation, among other factors. MMS may offer lower recurrence rates and improved survival when compared with historical controls for standard excision. Continued advances in MMS technique and immunohistochemical staining have allowed the technique to gain further support.
Department of Dermatology, State University of New York Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA. hui.andrea@gmail.com
Andrea M
AM
Hui
Michael
M
Jacobson
Orit
O
Markowitz
Norman A
NA
Brooks
Daniel M
DM
Siegel
D002712:Chlorides; D005404:Fixatives / Q000138:chemical synthesis; D005629:Frozen Sections / Q000379:methods*; D006801:Humans; D008545:Melanoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D015580:Mohs Surgery / Q000379:methods*; D021701:Sentinel Lymph Node Biopsy / Q000401:mortality; D012878:Skin Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D013194:Staining and Labeling / Q000379:methods*; D015996:Survival Rate; D017967:Zinc Compounds
D002712:Chlorides; D005404:Fixatives; D017967:Zinc Compounds; C016837:zinc chloride