Intestinal origin of sourdough Lactobacillus reuteri isolates as revealed by phylogenetic, genetic, and physiological analysis.
Lactobacillus reuteri is both a gut symbiont and a stable member of sourdough microbiota. This study employed multilocus sequence analysis and an analysis of host-specific physiological and genetic traits to assign five sourdough isolates to rodent- or human-specific lineages. Comparative genome hybridization revealed that the model sourdough isolate LTH2584 had a genome content very similar to that of the model rodent isolate 100-23. These results demonstrate that sourdough isolates of L. reuteri are of intestinal origin.
University of Alberta, Department of Agricultural, Food and Nutritional Science, Edmonton, Alberta, Canada.
Marcia Shu-Wei
MS
Su
Phaik Lyn
PL
Oh
Jens
J
Walter
Michael G
MG
Gänzle
D000818:Animals; D015373:Bacterial Typing Techniques; D055028:Comparative Genomic Hybridization; D005516:Food Microbiology; D041981:Gastrointestinal Tract / Q000382:microbiology*; D005798:Genes, Bacterial; D006801:Humans; D052200:Limosilactobacillus reuteri / Q000145:classification* / Q000235:genetics* / Q000502:physiology; D058885:Multilocus Sequence Typing; D012377:Rodentia