HIV treatment as prevention: debate and commentary--will early infection compromise treatment-as-prevention strategies?
Universal HIV testing and immediate antiretroviral therapy for infected individuals has been proposed as a way of reducing the transmission of HIV and thereby bringing the HIV epidemic under control. It is unclear whether transmission during early HIV infection--before individuals are likely to have been diagnosed with HIV and started on antiretroviral therapy--will compromise the effectiveness of treatment as prevention. This article presents two opposing viewpoints by Powers, Miller, and Cohen, and Williams and Dye, followed by a commentary by Fraser.
Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, United States of America.
Myron S
MS
Cohen
Christopher
C
Dye
Christophe
C
Fraser
William C
WC
Miller
Kimberly A
KA
Powers
Brian G
BG
Williams
D000208:Acute Disease; D019380:Anti-HIV Agents / Q000494:pharmacology* / Q000627:therapeutic use; D015658:HIV Infections / Q000188:drug therapy* / Q000517:prevention & control*; D006801:Humans; D013997:Time Factors; D016896:Treatment Outcome
D019380:Anti-HIV Agents