A case of isolated IgG4-related interstitial pneumonia: a new consideration for the cause of idiopathic nonspecific interstitial pneumonia.
The 2008 American Thoracic Society Project concluded that idiopathic nonspecific interstitial pneumonia (NSIP), once regarded as a "provisional" diagnosis, can be considered a distinct clinical entity. However, an increasing number of recent reports have shown a likely link between the entity of idiopathic NSIP and autoimmune diseases. Similarly, IgG4-related disease is being increasingly reported, and some of the lung lesions, at least radiologically, look like NSIP. A case of IgG4-related interstitial lung disease without other systemic manifestations of IgG4-related disease is reported. The existence of IgG4-related disease should, therefore, be taken into consideration as a possible differential diagnosis from NSIP. The cause of IgG4-related disease remains unknown, but we emphasize the importance of a clinically novel interstitial lung disease.
Department of Respiratory Medicine, Kobe City Medical Center, General Hospital, Kobe, Japan. Electronic address: kosuke624t@gmail.com.
Kosuke
K
Tanaka
Department of Respiratory Medicine, Kobe City Medical Center, General Hospital, Kobe, Japan.
Kazuma
K
Nagata
Department of Respiratory Medicine, Kobe City Medical Center, General Hospital, Kobe, Japan.
Keisuke
K
Tomii
Department of Clinical Pathology, Kobe City Medical Center, General Hospital, Kobe, Japan.
Yukihiro
Y
Imai
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D003937:Diagnosis, Differential; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism*; D017563:Lung Diseases, Interstitial / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology*; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D016896:Treatment Outcome
D000305:Adrenal Cortex Hormones; D007074:Immunoglobulin G; D011241:Prednisone