Palladium-catalyzed direct arylation of N-heteroarenes with arylsulfonyl hydrazides.
Hydrazides applied: A palladium-catalyzed direct C-H arylation of heteroarenes, with arylsulfonyl hydrazides as the arylating reagents, has been developed. The reaction is chemoselective, in that arylsulfonyl hydrazides containing halogen substituents can be employed without participation of the halogen substituent in the reaction. The method offers a straightforward approach to a variety of aryl-heteroaryl compounds.
Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, and State Key Laboratory of Biotherapy, West China Medical School, Sichuan University, Chengdu, P R China.
Bo
B
Liu
Jian
J
Li
Feijie
F
Song
Jingsong
J
You
D001190:Arylsulfonates / Q000737:chemistry*; D002384:Catalysis; D006834:Hydrazines / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D012997:Solvents
D001190:Arylsulfonates; D006834:Hydrazines; D047028:Macrocyclic Compounds; D012997:Solvents; D010165:Palladium