Paget's disease of the breast.
The initial presentation of Paget's disease of the breast is an eczematous lesion, similar to contact dermatitis, in the skin of the breast at the areola and/or nipple and is refractory to usual topical treatments. It is frequent among women, especially those in their 50s and 60s. Most cases are associated with an in situ or underlying invasive breast neoplasia. The histopathology is usually diagnostic, with immunohistochemistry useful for its differentiation from melanoma and other types of tumors. Treatment should always be surgical with invasive procedures for the effective and complete removal of the breast tumor.
Sector of Dermatology and Post Graduation Course of Dermatology, HUCFF/UFRJ and School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Juliana Corrêa
JC
Marques-Costa
Tullia
T
Cuzzi
Sueli
S
Carneiro
Lawrence Charles
LC
Parish
Marcia
M
Ramos-e-Silva
D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008545:Melanoma / Q000175:diagnosis*; D008875:Middle Aged; D010144:Paget's Disease, Mammary / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery