Impact of medication adherence on absenteeism and short-term disability for five chronic diseases.
OBJECTIVE
To estimate the impact of medication adherence on absenteeism and short-term disability among employees with chronic disease.


METHODS
Cross-sectional analysis of administrative health care claims, absenteeism, and short-term disability data using multivariate regression and instrumental variable models for five cohorts of employees: diabetes, hypertension, congestive heart failure, dyslipidemia, and asthma/chronic obstructive pulmonary disease. Adherence was defined as possessing medication on at least 80% of days during follow-up.


RESULTS
Adherent employees with diabetes, hypertension, dyslipidemia, and asthma/chronic obstructive pulmonary disease realized between 1.7 and 7.1 fewer days absent from work and between 1.1 and 5.0 fewer days on short-term disability. Absenteeism and short-term disability days by adherent employees with congestive heart failure were not significantly different from nonadherent employees with the condition in most specifications.


CONCLUSIONS
Appropriate management of chronic conditions can help employers minimize losses due to missed work.
Thomson Reuters, Ann Arbor, MI, USA. Ginger.Carls@thomsonreuters.com
Ginger S
GS
Carls
M Christopher
MC
Roebuck
Troyen A
TA
Brennan
Julie A
JA
Slezak
Olga S
OS
Matlin
Teresa B
TB
Gibson
D000041:Absenteeism; D001249:Asthma / Q000188:drug therapy / Q000453:epidemiology; D002908:Chronic Disease / Q000188:drug therapy* / Q000453:epidemiology; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy / Q000453:epidemiology; D050171:Dyslipidemias / Q000188:drug therapy / Q000453:epidemiology; D005260:Female; D006333:Heart Failure / Q000188:drug therapy / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy / Q000453:epidemiology; D018582:Sick Leave / Q000706:statistics & numerical data*; D016903:Drug Monitoring