Carbon-carbon bond formation: palladium-catalyzed oxidative cross-coupling of N-tosylhydrazones with allylic alcohols.
In the zone: Pd-catalyzed oxidative cross-coupling of N-tosylhydrazones with allylic alcohols leads to CC bond formation. A palladium-carbene migratory insertion is proposed to play the key role in this transformation. The reaction proceeds with readily available starting materials to afford substituted alkenes in a highly stereoselective manner.
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, PR China.
Huoji
H
Chen
Li
L
Huang
Wei
W
Fu
Xiaohang
X
Liu
Huanfeng
H
Jiang