[Association of diabetes and early failure of arteriovenous fistula in the end stage of renal diseases].
OBJECTIVE
To determine the association of diabetes and glycemic control with early failure of native arteriovenous fistula(AVF).


METHODS
266 patients with end stage renal diseases(ESRD) were recruited and divided into non-diabetic group (165), HbA1C < 7% group (51) and HbA1C > or = 7% group (50). Clinical indicators and early failure of AVF were examined.


RESULTS
In total, 63 (23.7%) patients had AVF early failure. The AVF early failure occurred in 18. 1% of patients in the non-diabetic group and 21.6% of patients in the HbA1C < 7% group, significantly less than that in the HbA1C > or = 7% group (44%). The COX regression model showed that increased HbA1C, total cholesterol (TC) and decreased high-density lipoprotein (HDL)increased the risk of AVF failure.


CONCLUSIONS
The levels of glycemic and serum lipid subfractions are associated with AVF early failure in ESRD patients. Good control of glycemic and lipid can lower the rates of AVF early failure.
Department of Nephrology, West China Hospital, Sichuan University , Chendu 610041,China.
Tian-lei
TL
Cui
Ren-zhong
RZ
Zhang
Fang
F
Liu
Wan-xin
WX
Tang
Ping
P
Fu
Li
L
Zhou
Ye
Y
Tao
Zhang-xue
ZX
Hu
D000328:Adult; D000368:Aged; D001166:Arteriovenous Shunt, Surgical / Q000009:adverse effects; D003928:Diabetic Nephropathies / Q000150:complications / Q000628:therapy*; D005260:Female; D006440:Hemofiltration / Q000379:methods*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies