Temporal lobe lesions and psychosis in multiple sclerosis.
Lesions in the temporal lobe are associated with psychiatric manifestations in multiple sclerosis. The authors describe this case of a young man with multiple sclerosis who presented with first-episode psychosis and had acute lesions in the temporal lobe. He was successfully treated with olanzapine and β-interferon.
Psychiatric Intensive Care Unit, Newsam Centre, Seacroft Hospital, West Yorkshire, Leeds, UK. aakanksha@gmail.com
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Yadav
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Zigmond
D000293:Adolescent; D000374:Aggression / Q000502:physiology*; D002552:Cerebral Ventricles / Q000473:pathology / Q000503:physiopathology; D003937:Diagnosis, Differential; D018450:Disease Progression; D004292:Dominance, Cerebral / Q000502:physiology; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D016899:Interferon-beta / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D019965:Neurocognitive Disorders / Q000175:diagnosis* / Q000503:physiopathology*; D010259:Paranoid Disorders / Q000503:physiopathology*; D013702:Temporal Lobe / Q000473:pathology* / Q000503:physiopathology*; D014754:Violence
D007155:Immunologic Factors; D016899:Interferon-beta