Churg-Strauss Syndrome: an evolving paradigm.
The Churg-Strauss Syndrome is an ANCA-associated vasculitis, an inflammatory multisystem disease with preference to the respiratory tract. Peripheral and tissue eosinophilia are the pathological hallmarks of this condition. The etiopathogenesis is unknown but some cytokines appear to play a central role and could be targets for new therapies.
Research Unit in Systemic Autoimmune Diseases, Vall D'hebron Research Institute, Hospital Vall D'hebron, Barcelona, Spain.
Marc
M
Ramentol-Sintas
Fernando
F
Martínez-Valle
Roser
R
Solans-Laqué
D000818:Animals; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000276:immunology; D001249:Asthma / Q000150:complications; D001402:B-Lymphocytes / Q000276:immunology / Q000378:metabolism; D002450:Cell Communication; D019742:Chemokines, CC / Q000276:immunology / Q000378:metabolism; D015267:Churg-Strauss Syndrome / Q000150:complications / Q000209:etiology*; D004804:Eosinophils / Q000276:immunology / Q000378:metabolism; D006801:Humans; D058504:Th17 Cells / Q000276:immunology / Q000378:metabolism; D018418:Th2 Cells / Q000276:immunology / Q000378:metabolism
D019268:Antibodies, Antineutrophil Cytoplasmic; D019742:Chemokines, CC