Pd(II)-catalyzed ortho arylation of 2-arylbenzothiazoles with aryl iodides via benzothiazole-directed C-H activation.
A novel and efficient method for the arylation of 2-arylbenzothiazoles is described via C-H activation. The desired C(Ar)-C(Ar) bond formation proceeded efficiently with good functional-group tolerance and high regioselectivity. Proposed mechanism for the arylation of 2-arylbenzothiazole is depicted.
Key Laboratory of Functional Small Organic Molecules, Ministry of Education and College of Chemistry & Chemical Engineering, Jiangxi Normal University, Nanchang, Jiangxi 330022, China.
Qiuping
Q
Ding
Huafang
H
Ji
Dan
D
Wang
Yuqing
Y
Lin
Weihua
W
Yu
Yiyuan
Y
Peng