Comparative experimental evaluation of the efficacy of Prostamol Uno and Samprost on rat model of chronic aseptic prostate inflammation.
Comparative experimental evaluation of the efficiency of prostatotropic drugs Prostamol Uno and Samprost on the model of the chronic aseptic prostate inflammation in rats was performed. It was established that peptide drug Samprost decelerates sclerotic processes in the prostate gland to a greater extent than herbal preparation Prostamol Uno. Both products equally stimulate secretory activity of the gland. Prostamol Uno, unlike Samprost, prevents the development of reduced sexual motivation, one of the complications of chronic prostatitis.
Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, St.Petersburg, Russia.
A V
AV
Pahomova
T G
TG
Borovskaja
T I
TI
Fomina
L A
LA
Ermolaeva
A V
AV
Vychuzhanina
O A
OA
Rumpel
O K
OK
Granstrem
O V
OV
Baranova
D000818:Animals; D021461:Animals, Outbred Strains; D000893:Anti-Inflammatory Agents / Q000494:pharmacology* / Q000627:therapeutic use; D003307:Copulation / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D008297:Male; D009929:Organ Size; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D011467:Prostate / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D011472:Prostatitis / Q000188:drug therapy*; D051381:Rats; D018709:Statistics, Nonparametric; D014020:Tissue Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D015032:Zinc / Q000378:metabolism
D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; C445500:Prostamol-Uno; D014020:Tissue Extracts; C576236:samprost; D015032:Zinc