Sweet's syndrome in a patient with haemophilia, HIV and hepatitis C infection.
Sweet's syndrome is a rare skin condition associated with both drug treatment and a number of different disease processes including haematological malignancies, inflammatory conditions and HIV infection. In this case report, we present a patient with HIV, haemophilia and hepatitis C who presented to our team with significant thrombocytopaenia and Sweet's syndrome. We discuss the difficulties with diagnosis and management in the context of multiple co-morbidities and suggest that both hepatitis C and HIV may have been aetiologically involved by suppressing platelet production and also causing bone marrow-driven neutrophilic disease.
Centre for Immunology and Infection, Hull York Medical School, University of York, York, UK.
A M
AM
Deasy
B
B
Walker
A M
AM
Layton
C J N
CJ
Lacey
D000328:Adult; D015658:HIV Infections / Q000097:blood / Q000150:complications* / Q000821:virology; D006467:Hemophilia A / Q000097:blood / Q000150:complications* / Q000821:virology; D006526:Hepatitis C / Q000097:blood / Q000150:complications* / Q000821:virology; D006801:Humans; D008297:Male; D016463:Sweet Syndrome / Q000097:blood* / Q000821:virology*; D013921:Thrombocytopenia / Q000097:blood / Q000821:virology