The current state of therapeutic drug trials in pregnancy.
The majority of pregnant women take prescription drugs during their pregnancy. Given the multitude of physiologic changes incumbent in pregnancy, accurate clinical trial data on drugs in pregnancy are crucial. This report summarizes the 264 registered clinical trials in the past two years. With many of these drug trials being pharmacokinetic and placebo-controlled studies, therapeutic drug trials are becoming more common.
Division of Clinical Pharmacology and Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN, USA.
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D000014:Abnormalities, Drug-Induced / Q000517:prevention & control; D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D018811:Maternal Exposure; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011297:Prenatal Exposure Delayed Effects / Q000139:chemically induced / Q000517:prevention & control; D055553:Prescription Drugs / Q000008:administration & dosage* / Q000009:adverse effects; D055815:Young Adult
D055553:Prescription Drugs