[Pain as adverse drug reaction].
We present a multidisciplinary (anaesthesiology--clinical pharmacy--bioinformatics) analysis of pain as possible adverse drug reaction taking different manifestations of pain, indication groups, relevance to the Austrian drug market and possible mechanistic influence of drugs on development and apprehension of pain into consideration.We designed an overview that shows how transmitters that play a part in nociception and antinociception can be influenced by drugs. This allows conclusions to the dolorigene potential of therapeutics.
Anstaltsapotheke, Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhügel, Wolkersbergenstrasse 1, 1130, Wien, Österreich. birgit.boehmdorfer@wienkav.at
Birgit
B
Böhmdorfer
Daniel
D
Schaffarzick
Marietta
M
Nagano
Susanne Melitta
SM
Janowitz
Ekkehard
E
Schweitzer
D015746:Abdominal Pain / Q000139:chemically induced / Q000453:epidemiology; D001317:Austria; D001416:Back Pain / Q000139:chemically induced; D002637:Chest Pain / Q000139:chemically induced / Q000453:epidemiology; D003430:Cross-Sectional Studies; D064420:Drug-Related Side Effects and Adverse Reactions; D006261:Headache / Q000139:chemically induced / Q000453:epidemiology; D006801:Humans; D010146:Pain / Q000139:chemically induced* / Q000453:epidemiology; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced