Dissociation of explicit and implicit long-term memory consolidation in semantic dementia: a case study.
We report a case study of a semantic dementia patient, whose episodic memory consolidation was tested over a 2-month period. The results reveal that despite early retention of information, the patient lost all explicit information of the newly learnt material after 2 weeks. By contrast, he retained implicit word information even after a 4-week delay. These findings highlight the critical time window of 2-4 weeks in which newly learnt information should be re-encoded in rehabilitations studies. The results also indicate that learnt information can be still accessed with implicit retrieval strategies when explicit retrieval fails.
Neuroscience Research Australia, Sydney, Australia.
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Mioshi
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Savage
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Hodges
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Hornberger
D001921:Brain / Q000473:pathology; D005500:Follow-Up Studies; D057180:Frontotemporal Dementia / Q000150:complications*; D006801:Humans; D008569:Memory Disorders / Q000175:diagnosis* / Q000209:etiology*; D057567:Memory, Long-Term / Q000502:physiology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D012016:Reference Values; D012660:Semantics; D014706:Verbal Learning