Graphene oxide wrapping on squaraine-loaded mesoporous silica nanoparticles for bioimaging.
Squaraine dyes were loaded inside mesoporous silica nanoparticles, and the nanoparticle surfaces were then wrapped with ultrathin graphene oxide sheets, leading to the formation of a novel hybrid material. The hybrid exhibits remarkable stability and can efficiently protect the loaded dye from nucleophilic attack. The biocompatible hybrid is noncytotoxic and presents significant potential for application in fluorescence imaging in vitro.
Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, 637371 Singapore.
Sivaramapanicker
S
Sreejith
Xing
X
Ma
Yanli
Y
Zhao
D001672:Biocompatible Materials / Q000737:chemistry; D015374:Biosensing Techniques; D003503:Cyclobutanes / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry; D006108:Graphite / Q000138:chemical synthesis / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D008856:Microscopy, Fluorescence; D053758:Nanoparticles / Q000737:chemistry*; D010087:Oxides / Q000138:chemical synthesis / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*; D013499:Surface Properties
D001672:Biocompatible Materials; D003503:Cyclobutanes; D005456:Fluorescent Dyes; D010087:Oxides; D010636:Phenols; C480596:squaraine; D012822:Silicon Dioxide; D006108:Graphite