Harmonization of description and classification of fetal observations: achievements and problems still unresolved: report of the 7th Workshop on the Terminology in Developmental Toxicology Berlin, 4-6 May 2011.
This article summarizes the 7th Workshop on the Terminology in Developmental Toxicology held in Berlin, May 4-6, 2011. The series of Berlin Workshops has been mainly concerned with the harmonization of terminology and classification of fetal anomalies in developmental toxicity studies. The main topics of the 7th Workshop were knowledge on the fate of anomalies after birth, use of Version 2 terminology for maternal-fetal observations and non-routinely used species, reclassification of "grey zone" anomalies and categorization of fetal observations for human health risk assessment. The paucity of data on health consequences of the postnatal permanence of fetal anomalies is relevant and further studies are needed. The Version 2 terminology is an important step forward and the terms listed in this glossary are considered also to be appropriate for most observations in non-routinely used species. Continuation of the Berlin Workshops was recommended. Topics suggested for the next Workshop were grouping of fetal observations for reporting and statistical analysis.
Federal Institute of Risk Assessment, Germany. Roland.Solecki@bfr.bund.de
Roland
R
Solecki
Stephane
S
Barbellion
Brigitte
B
Bergmann
Heinrich
H
Bürgin
Jochen
J
Buschmann
Ruth
R
Clark
Laura
L
Comotto
Antje
A
Fuchs
Ali Said
AS
Faqi
Ralph
R
Gerspach
Konstanze
K
Grote
Helen
H
Hakansson
Verena
V
Heinrich
Barbara
B
Heinrich-Hirsch
Thomas
T
Hofmann
Ulrich
U
Hübel
Thelma Helena
TH
Inazaki
Samia
S
Khalil
Thomas B
TB
Knudsen
Sabine
S
Kudicke
Wolfgang
W
Lingk
Susan
S
Makris
Simone
S
Müller
Francisco
F
Paumgartten
Rudolf
R
Pfeil
Elkiane Macedo
EM
Rama
Steffen
S
Schneider
Kohei
K
Shiota
Eva
E
Tamborini
Mariska
M
Tegelenbosch
Beate
B
Ulbrich
E A J
EA
van Duijnhoven
David
D
Wise
Ibrahim
I
Chahoud
D000014:Abnormalities, Drug-Induced / Q000145:classification*; D000818:Animals; D005333:Fetus / Q000002:abnormalities*; D006801:Humans; D018570:Risk Assessment; D009626:Terminology as Topic