Validation of the Spanish version of the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E).
BACKGROUND
To translate and validate into Spanish (Spain) the screening instrument of major depressive episodes (MDEs), Neurological Disorders Depression Inventory in Epilepsy (NDDI-E), in patients with epilepsy.


METHODS
A total of 121 outpatients, aged 18 years and older, with a diagnosis of epilepsy were included. The diagnosis of a current major depressive episode (MDE) was established with the Mini International Neuropsychiatric Interview (MINI).


RESULTS
A diagnosis of current MDE was established in 20% of the patients with the MINI. Receiver operator characteristics (ROC) analysis showed an area under the curve of 0.89, with an internal consistency of 0.78. At a cutoff score >13, 22% of patients were considered to suffer from MDE with the NDDI-E (sensitivity: 84%; specificity: 78%; positive predictive value: 64.7%; and negative predictive value: 92.2%).


CONCLUSIONS
The Spanish-Spain version of the NDDI-E appears to be a good screening instrument to identify MDE.
Epilepsy Unit, Hospital Clinico San Carlos, Madrid, Spain. danidicapua@gmail.com
Daniela
D
Di Capua
Maria Eugenia
ME
Garcia-Garcia
Abilio
A
Reig-Ferrer
Manuel
M
Fuentes-Ferrer
Rafael
R
Toledano
Antonio
A
Gil-Nagel
Sara
S
Garcia-Ptaceck
Monica
M
Kurtis
Andres M
AM
Kanner
Irene
I
Garcia-Morales
D000328:Adult; D019540:Area Under Curve; D003863:Depression / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology*; D004827:Epilepsy / Q000150:complications* / Q000453:epidemiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012372:ROC Curve; D015203:Reproducibility of Results; D013030:Spain / Q000453:epidemiology; D014175:Translating