A second case report of lleuprolide acetate for depot suspension-induced mania.
This is the second published case report of Lleuprolide acetate for depot suspension (LD)-induced mania. Both reports detail a patient with a prior psychiatric history of both depressive and hypomanic episodes. While depression is a predictable and documented side effect of LD and menopause (especially in those with a previoushistory of symptoms), manic reactions are rare and unexplained. Possible causative mechanismsbehind the LD-induced manic episodes are discussed, and we suggest that patients with a single previous hypomanic episode are at risk for LD-induced mania.
Monika M
MM
Wahi
Robert C
RC
Skeate
Steven B
SB
Goldin
Carlos A
CA
Santana
D000085:Acetates; D001714:Bipolar Disorder / Q000188:drug therapy; D003866:Depressive Disorder; D006801:Humans
D000085:Acetates