Neoplastic meningitis and metastatic epidural spinal cord compression.
Neoplastic meningitis, commonly referred to as carcinomatosis meningitis, leukemic meningitis, or lymphomatous meningitis, is the third most common central nervous system metastatic complication of systemic cancer and is the most morbid of central nervous system metastases. The disease is challenging to treat for a variety of reasons, including challenges in making a diagnosis of neoplastic meningitis and lack of standardized treatment due to the paucity of clinical trials addressing treatment of neoplastic meningitis.
Division of Neuro-Oncology, Department of Neurology, University of Washington, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. chambemc@u.washington.edu
Marc C
MC
Chamberlain
D015174:Epidural Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D006801:Humans; D055756:Meningeal Carcinomatosis / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D013117:Spinal Cord Compression / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy