Reactivation West Nile virus infection-related chorioretinitis.
West Nile Virus is a relatively uncommon infection that can involve retinal and choroidal inflammation leading to photopsias, photophobia, and orbital pain. The diagnosis is made by clinical history, serology, and characteristic funduscopic exam and fluorescein angiography findings. Treatment involves primarily supportive care as there are no known effective anti-viral agents. Visual recovery is usually full. Here we present a case of West Nile Virus Infection Related chorioretinitis that demonstrated active linear chorioretinal lesions approximately one year after the initial infection was diagnosed and treated. The patient noted new onset blurry vision and floaters for two weeks prior to presentation. Antibody titers to West Nile Virus increased from baseline levels indicating active infection. This represents the first case of reactivation West Nile Virus Infection Related chorioretinitis that has been documented.
Jules Stein Eye Institute, UCLA Department of Ophthalmology, Los Angeles, CA 90095, USA. Beardsley@jsei.ucla.edu
Robert
R
Beardsley
Colin
C
McCannel
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D002825:Chorioretinitis / Q000175:diagnosis / Q000821:virology*; D015828:Eye Infections, Viral / Q000175:diagnosis / Q000821:virology*; D006801:Humans; D008297:Male; D014775:Virus Activation; D014786:Vision Disorders / Q000175:diagnosis; D014901:West Nile Fever / Q000150:complications*; D014902:West Nile virus / Q000276:immunology / Q000302:isolation & purification
D000914:Antibodies, Viral