Immunization in special populations.
In summary, immunizations in special populations require understanding the underlying disease and how it might affect the immune system's ability to mount an antibody response to vaccines or predispose certain patient populations to developing certain serious infections. There is still a great need for research on the optimal timing of vaccines after transplants, how to assess protection and development of a protective antibody response after immunization, and whether certain groups (eg, HIV) need to be revaccinated after a certain amount of time if their antibody levels decline. In addition, there are limited data on efficacy of the newer vaccines in these special patient populations, which also requires further investigation.
Department of Pediatric Infectious Diseases and Immunology, University of Florida, Jacksonville, 32209, USA.
Michael A
MA
Miller
Mobeen H
MH
Rathore
D002648:Child; D002675:Child, Preschool; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D010372:Pediatrics / Q000379:methods; D017410:Practice Guidelines as Topic; D014611:Vaccination / Q000379:methods / Q000592:standards*; D014612:Vaccines / Q000145:classification / Q000276:immunology
D014612:Vaccines