Rat hepatic aldehyde dehydrogenase in normal conditions and thermal injury: partial purification, property investigation.
Catalytical properties of aldehyde dehydrogenase were studied using preparations of this enzyme, obtained from control rats and rats with thermal injury. Aldehyde dehydrogenase was shown to participate in the metabolism of aromatic and aliphatic aldehydes. Kinetic characteristics of the enzyme with different substrates were studied under normal conditions and in thermal burn injury.
Nizhny Novgorod Institute of Traumatology and Orthopedics, Federal Agency of High Technological Medical Care, Russia. sannag5@mail.ru
A G
AG
Solovyeva
Yu V
YV
Zimin
A V
AV
Zaskanova
D000444:Aldehyde Dehydrogenase / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism; D000447:Aldehydes / Q000378:metabolism*; D000818:Animals; D002056:Burns / Q000201:enzymology*; D002848:Chromatography, DEAE-Cellulose; D002850:Chromatography, Gel; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D051381:Rats; D017208:Rats, Wistar; D013379:Substrate Specificity
D000447:Aldehydes; D000444:Aldehyde Dehydrogenase