Antimicrobial activity of Calendula officinalis petal extracts against fungi, as well as Gram-negative and Gram-positive clinical pathogens.
The aim of the present study was to assess the antimicrobial activity of methanol and ethanol extracts of pot marigold (Calendula officinalis) petals against clinical pathogens. The antimicrobial potential of C. officinalis extracts was evaluated against a panel of microorganisms isolated from patients at the Belfast City Hospital (BCH), including bacteria and fungi, using disc diffusion assay. Methanol extract of C. officinalis exhibited better antibacterial activity against most of the bacteria tested, than ethanol extract. Both methanol and ethanol extracts showed excellent antifungal activity against tested strains of fungi, while comparing with Fluconazole.
Centre of Molecular Biosciences, Institute of Biomedical Sciences Research, University of Ulster, Coleraine BT52 1SA, UK.
Efstratios
E
Efstratiou
Abdullah I
AI
Hussain
Poonam S
PS
Nigam
John E
JE
Moore
Muhammad A
MA
Ayub
Juluri R
JR
Rao
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D020838:Calendula; D035264:Flowers; D015725:Fluconazole / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects*; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006801:Humans; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D010936:Plant Extracts; D015725:Fluconazole