Raltegravir-induced DRESS syndrome.
DRESS syndrome (drug reaction with eosinophilia and systemic symptoms) is a life-threatening adverse drug reaction. Raltegravir is an integrase inhibitor used in HIV-1 infection. We report on a patient who developed a DRESS syndrome under raltegravir treatment, which was identified as a probable case of DRESS on the basis of Kardaun and Naranjo scores. The presented case is the first description of a proven raltegravir-induced DRESS syndrome.
CIC de Vaccinologie Cochin-Pasteur, Hôpital Cochin, 27, rue du Faubourg Saint Jacques, F75014 Paris, France. pierre.loulergue@cch.aphp.fr
Pierre
P
Loulergue
Olivier
O
Mir
D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004802:Eosinophilia / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans; D008875:Middle Aged; D011760:Pyrrolidinones / Q000008:administration & dosage / Q000009:adverse effects*; D000068898:Raltegravir Potassium
D019380:Anti-HIV Agents; D011760:Pyrrolidinones; D000068898:Raltegravir Potassium