Ribonucleoside 3'-phosphates as pro-moieties for an orally administered drug.
Medical Scientist Training Program and Molecular & Cellular Pharmacology Graduate Training Program, University of Wisconsin-Madison, 750 Highland Avenue, Madison, WI 53705, USA.
Michael J
MJ
Palte
Amy K F
AK
Davis
Nicholas A
NA
McGrath
Carol A
CA
Spiegel
Ronald T
RT
Raines
D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D001442:Bacteroides Infections / Q000188:drug therapy; D001441:Bacteroides fragilis / Q000187:drug effects; D006801:Humans; D007700:Kinetics; D008795:Metronidazole / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D008826:Microbial Sensitivity Tests; D011355:Prodrugs / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D012259:Ribonuclease, Pancreatic / Q000378:metabolism; D012265:Ribonucleotides / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D011355:Prodrugs; D012265:Ribonucleotides; D008795:Metronidazole; D012259:Ribonuclease, Pancreatic