Pregnancy after cardiac transplantation.
More women are reporting pregnancy following heart transplantation. Although successful outcomes have been reported for the mother, transplanted heart, and newborn, such pregnancies should be considered high risk. Hypertension, preeclampsia, and infection should be treated. Vaginal delivery is recommended unless cesarean section is obstetrically necessary. Most outcomes are live births, and long-term follow-up of children show most are healthy and developing well. Maternal survival, independent of pregnancy-related events, should be part of prepregnancy counseling.
Department of Surgery, Thomas Jefferson University, 1025 Walnut Street, Suite 605, Philadelphia, PA 19107, USA.
Scott W
SW
Cowan
John M
JM
Davison
Cataldo
C
Doria
Michael J
MJ
Moritz
Vincent T
VT
Armenti
D001942:Breast Feeding; D003267:Contraception / Q000379:methods; D003376:Counseling; D036861:Delivery, Obstetric; D003925:Diabetic Angiopathies / Q000517:prevention & control; D005260:Female; D006084:Graft Rejection / Q000517:prevention & control; D006331:Heart Diseases / Q000601:surgery*; D016027:Heart Transplantation; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006973:Hypertension / Q000517:prevention & control; D007165:Immunosuppression Therapy / Q000379:methods; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D011183:Postoperative Complications / Q000628:therapy; D011225:Pre-Eclampsia; D016742:Preconception Care / Q000379:methods; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology*; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control; D011256:Pregnancy Outcome; D011295:Prenatal Care / Q000379:methods; D012042:Registries; D013997:Time Factors
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D007166:Immunosuppressive Agents