Modification without impact: a case study in clinical assay failure due to lipemia.
Quotient Bioresearch Ltd, Rushden, Northamptonshire NN10 6ER, UK. g.clark@cyprotex.com
Graeme T
GT
Clark
Paul J
PJ
Russell
Steven
S
Westwood
D000097:Acetonitriles / Q000737:chemistry; D000818:Animals; D002623:Chemistry Techniques, Analytical / Q000379:methods*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D029965:Gentianaceae / Q000737:chemistry; D006027:Glycosides / Q000097:blood*; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood*; D059625:Liquid-Liquid Extraction / Q000379:methods; D000432:Methanol / Q000737:chemistry; D008738:Methyl Ethers / Q000737:chemistry; D051379:Mice; D010743:Phospholipids / Q000097:blood; D010936:Plant Extracts / Q000737:chemistry; D011817:Rabbits; D051381:Rats; D052616:Solid Phase Extraction / Q000379:methods*; D013256:Steroids / Q000097:blood*; D053719:Tandem Mass Spectrometry / Q000379:methods
D000097:Acetonitriles; D006027:Glycosides; D008738:Methyl Ethers; D010743:Phospholipids; D010936:Plant Extracts; D013256:Steroids; C043243:methyl tert-butyl ether; D000432:Methanol; C032159:acetonitrile