Changes in resting-state functionally connected parietofrontal networks after videogame practice.
Neuroimaging studies provide evidence for organized intrinsic activity under task-free conditions. This activity serves functionally relevant brain systems supporting cognition. Here, we analyze changes in resting-state functional connectivity after videogame practice applying a test-retest design. Twenty young females were selected from a group of 100 participants tested on four standardized cognitive ability tests. The practice and control groups were carefully matched on their ability scores. The practice group played during two sessions per week across 4 weeks (16 h total) under strict supervision in the laboratory, showing systematic performance improvements in the game. A group independent component analysis (GICA) applying multisession temporal concatenation on test-retest resting-state fMRI, jointly with a dual-regression approach, was computed. Supporting the main hypothesis, the key finding reveals an increased correlated activity during rest in certain predefined resting state networks (albeit using uncorrected statistics) attributable to practice with the cognitively demanding tasks of the videogame. Observed changes were mainly concentrated on parietofrontal networks involved in heterogeneous cognitive functions.
Departamento de Psicología Biológica y Salud, Universidad Autónoma de Madrid, Madrid, Spain; Área de Neuroimagen, Fundación CIEN-Fundación Reina Sofía, Madrid, Spain.
Kenia
K
Martínez
Ana Beatriz
AB
Solana
Miguel
M
Burgaleta
Juan Antonio
JA
Hernández-Tamames
Juan
J
Alvarez-Linera
Francisco J
FJ
Román
Eva
E
Alfayate
Jesús
J
Privado
Sergio
S
Escorial
María A
MA
Quiroga
Sherif
S
Karama
Pierre
P
Bellec
Roberto
R
Colom
D000293:Adolescent; D001931:Brain Mapping; D003071:Cognition / Q000502:physiology; D005260:Female; D005625:Frontal Lobe / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007360:Intelligence; D008279:Magnetic Resonance Imaging; D009434:Neural Pathways / Q000502:physiology*; D009483:Neuropsychological Tests; D010296:Parietal Lobe / Q000502:physiology*; D011214:Practice, Psychological; D025341:Principal Component Analysis; D012044:Regression Analysis; D015203:Reproducibility of Results; D012146:Rest / Q000502:physiology*; D018910:Video Games; D055815:Young Adult