[Study of arousal index in children with sleep-disordered breathing].
OBJECTIVE
To explore which index is more suitable to show the degree of sleep fragment in children with sleep-disordered breathing (SDB).


METHODS
Between October 2009 and August 2011, Forty-five children (4 - 8 years) who were diagnosed as obstructive sleep apnea hypopnea syndrome (OSAHS) were enrolled in OSAHS group[obstructive apnea index (OAI) > 1 times/h or apnea hypopnea index (AHI) > 5 times/h, lowest oxygen saturation (LSaO2) < 0.92] and 54 children were enrolled in SDB group (1 ≤ AHI ≤ 5 times/h and OAI ≤ 1 times/h), 18 children with chorditis nodules made up control group (AHI < 1 times/h and LSaO2 ≥ 0.92, without SDB-related history). The difference of respiratory arousal index (RAI), spontaneous arousal index (SAI), total arousal index (ARtotI) and sleep pressure score (SPS) were compared among three groups. The correlation between RAI, SAI, ARtotI, SPS and AHI were also analyzed. Furthermore, RAI, SAI, ARtotI and SPS were compared before and after operation in 14 OSAHS children with detailed pre- and after polysomnography data.


RESULTS
The difference of SAI and ARtotI between SDB group and OSAHS group and ARtotI between OSAHS group and control group were not significant (P > 0.017), except this, the difference of other index between any two groups or SAI and ARtotI between otherwise two groups were significant (P < 0.017). RAI and SPS was correlated with AHI (coefficient correlation: 0.751, 0.829, P was 0.000). RAI and SPS decreased after operation and the difference was significant (Z were -3.045 and -2.982, P were 0.002 and 0.003). The difference of sleep structure was not significant.


CONCLUSIONS
RAI and SPS were more suitable to show the degree of sleep fragment than other arousal index.
Department of Otorhinolaryngology, Guangzhou Women and Children's Medical Center, Guangzhou 510120, China.
Zhen-yun
ZY
HUANG
Da-bo
DB
LIU
Jian-wen
JW
ZHONG
Jing
J
ZHOU
Jia-jian
JJ
XU
Yu-ping
YP
ZHOU
Shu-yao
SY
QIU
Shao-feng
SF
LIU
D001143:Arousal; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D017286:Polysomnography; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology*