Problem-solving test: the role of ubiquitination in epidermal growth factor receptor trafficking.
Terms to be familiar with before you start to solve the test: growth factor signaling, epidermal growth factor, tyrosine protein kinase, tyrosine phosphorylation, ubiquitin, monoubiquitination, polyubiquitination, site-directed mutagenesis, transfection, expression vector, cDNA, immunoprecipitation, SDS-polyacrylamide gel electrophoresis, Western blotting, radioactive labeling, receptor-mediated endocytosis.
Department of Medical Biology, Medical School, University of Pécs, H-7624 Pécs, Hungary. jozsef.szeberenyi@aok.pte.hu.
József
J
Szeberényi
D004591:Electrophoresis, Polyacrylamide Gel; D066246:ErbB Receptors / Q000378:metabolism*; D006801:Humans; D047468:Immunoprecipitation; D018794:Problem-Based Learning / Q000379:methods*; D025801:Ubiquitin / Q000378:metabolism; D054875:Ubiquitination
D025801:Ubiquitin; D066246:ErbB Receptors