The role of autofluorescence bronchoscopy in monitoring a tumorous lesion in the bronchial mucosa: a case report.
BACKGROUND
Autofluorescence bronchoscopy (AFB) is a diagnostic procedure that is included in all diagnostic algorithms discovering precancerous lesions in the large airways.


METHODS
We presented a 71-year-old patient submitted to exploration due to prolonged cough. Both noninvasive and invasive pulmonary diagnostic management was carried out. On bronchoscopy, an endobronchial mass was detected in the apical bronchus. A positive endoscopy finding indicated AFB which disclosed a fluorescence alteration of the tumor mucosa and the former bronchoscopy site. Histopathological analysis of the catheter biopsy obtained samples from the right upper lobe confirmed fibrinous purulent pneumonia in organization. The applied treatment resulted in regression of both symptoms and the lesion in the right upper lobe. Due to a positive AFB finding, the patient was regularly observed over the following three years, having had three control AFB to monitor the initial finding.


CONCLUSIONS
AFB may be utilized in the routine of everyday practice to assess the spread of the disease, as well as in the postsurgical and long-term follow-up of operated patients. The procedure may also be applied to enable an easier and more reliable observation of patients with suspicious endobronchial lesions, smokers with altered fluorescence of the bronchial mucosa, and chronic patients.
Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia. dskrbic@gmail.com
Dusan
D
Skrbić
Goran
G
Stojanović
Djordje
D
Povazan
Mirna
M
Djurć
Zivka
Z
Eri
D000368:Aged; D001980:Bronchi / Q000473:pathology; D001984:Bronchial Neoplasms / Q000175:diagnosis* / Q000473:pathology; D001999:Bronchoscopy / Q000379:methods; D005453:Fluorescence; D006801:Humans; D008297:Male; D011230:Precancerous Conditions / Q000175:diagnosis*; D020545:Respiratory Mucosa / Q000473:pathology