[Comprehensive chemical pattern recognition of pantagirus semen].
OBJECTIVE
To establish a method of comprehensive chemical pattern recognition of plantain seed via HPLC fingerprint, principal component analysis (PCA) and cluster analysis.


METHODS
The chromatographic separation was performed on a C18 column (4.6 mm x 250 mm, 5 microm). The mobile phase was a mixture of acetonitrile-0.5% acetic acid aqueous solution in gradient elution. The HPLC fingerprint of ethyl acetate fraction of 24 batches Plantaginis Semen from different habits and varieties was set up and 10 common peaks were obtained.


RESULTS
The result of the principal component analysis (PCA) and cluster analysis is similar but there is disparity between them.


CONCLUSIONS
The method could be used for the quality control and comprehensive evaluation of Plantaginis Semen.
School of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China. jzlgm88@163.com
Guangming
G
Luo
Jinxiang
J
Zeng
Jixiao
J
Zhu
D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D025341:Principal Component Analysis
D004365:Drugs, Chinese Herbal