A comparison of electrocochleography and high-pass noise masking of auditory brainstem response for diagnosis of Ménière's disease.
OBJECTIVE
To study differences between electrocochleography (ECochG) and cochlear hydrops analysis masking procedure (CHAMP) in diagnosis of Ménière's disease.


METHODS
Retrospective case review from a tertiary referral center.


METHODS
Thirty patients suspected to have Ménière's disease were assessed by ECochG and CHAMP tests.


RESULTS
Positivity of ECochG with SP/AP amplitude ratio >.40 or >.35 was compared with CHAMP V-delay or CHAMP R × D. Positive ECochG results were found in 43% (>.40 SP/AP ratio) and 63% (>.35 SP/AP ratio) of patients, comparing to positive CHAMP V delay in 27% and CHAMP R × D in 30% of patients. A significant difference (p <.01) was found between ECochG and CHAMP in diagnostic sensitivity. Also, a positive inter-aural correlation was found in CHAMP results (p <.003), but not in ECochG (p =.082) results.


CONCLUSIONS
ECochG is a more sensitive test than CHAMP in detecting the presence of endolymphatic hydrops in Ménière's patients. CHAMP covaried interaurally in unilateral Ménière's patients whereas ECochG did not.
Professional Hearing Services-The Dizziness and Balance Center, Falls Church, Virginia, USA.
Donnia
D
Zack-Williams
Richard M
RM
Angelo
Qing
Q
Yue
D001300:Audiometry, Evoked Response; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000175:diagnosis*; D008875:Middle Aged; D012189:Retrospective Studies