[Preparation of molecularly imprinted polypyrrole/Fe3O4 composite material and its application in recognition of tryptophan enantiomers].
Ferrosoferric oxide (Fe(3)O(4)) magnetic material was first synthesized, and then the in-situ chemical polymerization of pyrrole was carried out on the surface of Fe(3)O(4) by using pyrole and L-tryptophan (L-Trp) as the functional monomer and templates, respectively. As a result, molecularly imprinted polypyrrole/Fe(3)O(4) composite material was obtained. This composite material was separated from the solution because of its magnetic property. Polypyrrole in the composite was overoxidized in 1 mol/L NaOH solution by applying a potential of 1.0 V, and thus L-Trp templates were de-deoped from the composite. Scanning electron microscopy (SEM), X-ray diffraction (XRD) and electrochemical methods were employed to characterize the composite. The solution containing L- or D-Trp was pumped through a porous ceramic tube packed with the composite, separately. High performance liquid chromatography (HPLC) was adopted for the detection of L- or D-Trp in the eluate, and the results indicated that the enrichment ability of the composite for L-Trp was almost 2 times that of D-Trp. Therefore, the electro-magnetic composite material has potential applications as chromatographic stationary phase for chiral recognition.
School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China.
Zhidong
Z
Chen
Xueling
X
Shan
Yong
Y
Kong
D002851:Chromatography, High Pressure Liquid; D052203:Ferrosoferric Oxide / Q000138:chemical synthesis* / Q000737:chemistry; D054802:Molecular Imprinting; D053761:Nanocomposites / Q000737:chemistry; D011108:Polymers / Q000138:chemical synthesis*; D011758:Pyrroles / Q000138:chemical synthesis*; D013237:Stereoisomerism; D014364:Tryptophan / Q000737:chemistry* / Q000302:isolation & purification
D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole; D014364:Tryptophan; D052203:Ferrosoferric Oxide