Seroepidemiological surveillance of Burkholderia pseudomallei in Bangladesh.
Melioidosis (Burkholderia pseudomallei infection) has yet to be demonstrated systematically in Bangladesh. A prospective, cross-sectional serological survey was conducted in 2010 at six Bangladeshi hospitals. Age, gender, occupation and residential address were recorded. Of 1244 patients, 359 (28.9%) were positive for B. pseudomallei by indirect haemagglutination assay. Farmers had an increased risk of seropositivity (risk ratio=1.4, 95% CI 1.0-1.8; p=0.03). There was no clear geographic clustering of seropositives. Melioidosis should be considered as a possible cause of febrile illness in Bangladesh. Further studies are needed to establish the incidence of clinical disease and distribution of environmental risk.
Mahidol-Oxford Tropical Medicine Research Unit (MORU), Faculty of Tropical Medicine, Mahidol University, 3/F, 60th Anniversary Chalermprakiat Bldg, 420/6 Rajvithi Road, Rajathevi, Bangkok 10400, Thailand. rapeephan.maude@gmail.com
Rapeephan R
RR
Maude
Richard J
RJ
Maude
Aniruddha
A
Ghose
Md Robed
MR
Amin
Md Belalul
MB
Islam
Mohammad
M
Ali
Md Shafiqul
MS
Bari
Md Ishaque
MI
Majumder
Vanaporn
V
Wuthiekanan
Arjen M
AM
Dondorp
Robin L
RL
Bailey
Nicholas P J
NP
Day
M Abul
MA
Faiz
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000097:blood*; D000942:Antigens, Bacterial / Q000097:blood*; D001459:Bangladesh / Q000453:epidemiology; D016957:Burkholderia pseudomallei / Q000276:immunology / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008554:Melioidosis / Q000097:blood* / Q000453:epidemiology*; D008875:Middle Aged; D011159:Population Surveillance; D011446:Prospective Studies; D055815:Young Adult
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial