Towards a zinc-catalyzed asymmetric hydrogenation/transfer hydrogenation of imines.
The first asymmetric hydrogenation/transfer hydrogenation of imines to amines using zinc(II) triflate in combination with chiral ligands is described. The monodentate binaphthophosphepine ligand (3 g) provided the highest enantioselectivities. Using different imines, the corresponding amines were obtained in moderate yields and enantioselectivities.
Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Straße 29a, 18059 Rostock, Germany.
Svenja
S
Werkmeister
Steffen
S
Fleischer
Kathrin
K
Junge
Matthias
M
Beller
D002384:Catalysis; D006865:Hydrogenation; D007097:Imines / Q000737:chemistry*; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010084:Oxidation-Reduction; D013237:Stereoisomerism; D015032:Zinc / Q000737:chemistry*
D007097:Imines; D009942:Organometallic Compounds; D015032:Zinc