[A new look at reactions with participation of metal-porphyrines].
Reactions ofnucleophilic substitution and enzymatic processes with participation of metal-porphyrins (MP) are considered from the point of view of Zn-tetraphenylporphin (Zn-TPhP) coordination with corresponding ligand/nucleophyl/substrate/base. Linear correlations perform between kinetic parameters of process of coordination of Zn-TPhP in chloroform (constants of stability) and reactions of nucleophilic substitution both in aqueous and organic solvents with participation ofpyridines, N-oxides ofpyridines, anilines, primary amines and oxidation of anilines by horseradish peroxidase in aqueous solutions (rate constants). Thermodynamic parameters of complexation and nucleophilic substitution mutually correlate linearly in the case of pyridines, anilines and primary amines.
V P
VP
Andreev
P S
PS
Sobolev
D003285:Contractile Proteins / Q000737:chemistry; D006735:Horseradish Peroxidase / Q000737:chemistry*; D007700:Kinetics; D008665:Metalloporphyrins / Q000737:chemistry*; D010084:Oxidation-Reduction; D015032:Zinc / Q000737:chemistry*
D003285:Contractile Proteins; D008665:Metalloporphyrins; C095886:anillin; D006735:Horseradish Peroxidase; D015032:Zinc