Case report: Trabecular juvenile ossifying fibroma presenting as a sellar mass.
A 15-year-old girl presented with left occulomotor nerve palsy and was found to have a space occupying lesion of the sellar region with invasion of the left cavernous sinus. A transsphenoidal approach lead to subtotal removal of a solid tumor with some remnants in the cavernous sinus and revealed the diagnosis of trabecular juvenile ossifying fibroma (JOF). A repeat magnetic resonance imaging was obtained within 1 month that showed intrasellar recurrence and growing tumor in the cavernous sinus. Therefore, a combined transsphenoidal and transcranial approach was performed to more aggressively remove the tumor. Subsequently, adjuvant proton radiotherapy was performed. JOF of the trabecular type is a rare fibro-osseous lesion of the craniofacial skeleton almost exclusively occurring in the maxilla or the mandible. To our knowledge, this is the first case of this tumor entity presenting as a sellar mass.
Department of Neurosurgery, University Hospital Zurich, Zurich, Switzerland.
Marian Christoph
MC
Neidert
Christoph Michael
CM
Woernle
Jan-Karl
JK
Burkhardt
Regina
R
Reimann
Eugen
E
Hug
René-Ludwig
RL
Bernays
D000293:Adolescent; D015875:Anisocoria / Q000209:etiology; D001763:Blepharoptosis / Q000209:etiology; D003131:Combined Modality Therapy; D004172:Diplopia / Q000209:etiology; D005260:Female; D018214:Fibroma, Ossifying / Q000473:pathology* / Q000601:surgery; D006261:Headache / Q000209:etiology; D006728:Hormones / Q000097:blood; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D009364:Neoplasm Recurrence, Local; D019635:Neurosurgical Procedures; D061766:Proton Therapy; D012658:Sella Turcica / Q000473:pathology* / Q000601:surgery; D014129:Trabecular Meshwork / Q000473:pathology
D006728:Hormones