Axon trapping: constructing the visual system one layer at a time.
The molecular mechanisms that instruct the formation of synaptic layers are only incompletely understood. In this issue of Neuron, Timofeev et al. (2012) describe an instructive role for the guidance molecule Netrin and its receptor Frazzled in mediating layer-specific targeting of one photoreceptor cell type in the Drosophila visual system.
Department of Neurobiology, Stanford University, Stanford, CA 94305, USA.
Tina
T
Schwabe
Thomas R
TR
Clandinin