Gold catalysis: non-spirocyclic intermediates in the conversion of furanynes by the formal insertion of an alkyne into an aryl-alkyl C-C single bond.
It takes al-kynes: The formation of furyl-substituted heterocycles from furanynes with donor groups on the furan-alkyne tether and mechanistic control experiments indicate the involvement of open-chained carbenium ions in the overall insertion of an alkyne into a C-C bond, rather than the usual spirocyclic intermediates.
Organisch-Chemisches Institut, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany. hashmi@hashmi.de
A Stephen K
AS
Hashmi
Tobias
T
Häffner
Weibo
W
Yang
Sreekumar
S
Pankajakshan
Sascha
S
Schäfer
Lara
L
Schultes
Frank
F
Rominger
Wolfgang
W
Frey