Immunological complications of obesity.
Current approaches for the treatment of obesity, including diet and lifestyle changes, have not been successful in curtailing the obesity epidemic. The higher incidence of inflammation-associated chronic disease and greater susceptibility to infection in obese people represents a growing health threat. Improved understanding of the immunological processes that regulate obesity may yield new treatments for obesity-associated disorders.
Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA. thirumala-devi.kanneganti@stjude.org
Thirumala-Devi
TD
Kanneganti
Vishwa Deep
VD
Dixit
D000273:Adipose Tissue / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology; D005075:Biological Evolution; D004032:Diet; D006801:Humans; D058847:Inflammasomes / Q000276:immunology / Q000378:metabolism; D007964:Leukocytosis; D008019:Life Style; D008262:Macrophage Activation; D008264:Macrophages / Q000276:immunology; D008407:Mast Cells / Q000276:immunology; D009504:Neutrophils / Q000276:immunology; D009765:Obesity / Q000150:complications / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D058847:Inflammasomes