Angioneurotic orolingual oedema following thrombolysis in acute ischaemic stroke.
Alteplase used for thrombolysis in ischaemic stroke may be complicated by orolingual acute angioedema (OAA), a rare but potentially life-threatening side effect. We report the case of a 32-year-old woman who over 24 h experienced OAA after thrombolysis for an acute ischaemic left hemispheric stroke. We discuss the pathophysiology of this rare phenomenon.
Department of Neurology, Memory Center, Lille University Hospital, Lille, France.
D
D
Wallon
P
P
Girardie
S
S
Bombois
C
C
Lucas
D000328:Adult; D000799:Angioedema / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D005343:Fibrinolytic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D020521:Stroke / Q000188:drug therapy*; D010959:Tissue Plasminogen Activator / Q000009:adverse effects* / Q000627:therapeutic use; D014060:Tongue Diseases / Q000139:chemically induced* / Q000175:diagnosis
D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator