Rational design of HIV vaccines and microbicides: report of the EUROPRISE annual conference 2011.
Europrise is a Network of Excellence supported by the European Commission within the 6th Framework programme from 2007 to 2012. The Network has involved over 50 institutions from 13 European countries together with 3 industrial partners and 6 African countries. The Network encompasses an integrated program of research, training, dissemination and advocacy within the field of HIV vaccines and microbicides. A central and timely theme of the Network is the development of the unique concept of co-usage of vaccines and microbicides. Training of PhD students has been a major task, and some of these post-graduate students have here summarized novel ideas emanating from presentations at the last annual Europrise meeting in Prague. The latest data and ideas concerning HIV vaccine and microbicide studies are included in this review; these studies are so recent that the majority have yet to be published. Data were presented and discussed concerning novel immunisation strategies; microbicides and PrEP (alone and in combination with vaccines); mucosal transmission of HIV/SIV; mucosal vaccination; novel adjuvants; neutralizing antibodies; innate immune responses; HIV/SIV pathogenesis and disease progression; new methods and reagents. These - necessarily overlapping topics - are comprehensively summarised by the Europrise students in the context of other recent exciting data.
Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden. britta.wahren@ki.se
Nicolas
N
Ruffin
Marie
M
Borggren
Zelda
Z
Euler
Fabio
F
Fiorino
Katrijn
K
Grupping
David
D
Hallengärd
Aneele
A
Javed
Kevin
K
Mendonca
Charlotte
C
Pollard
David
D
Reinhart
Elisa
E
Saba
Enas
E
Sheik-Khalil
Annette
A
Sköld
Serena
S
Ziglio
Gabriella
G
Scarlatti
Frances
F
Gotch
Britta
B
Wahren
Robin J
RJ
Shattock
D016915:AIDS Vaccines; D000818:Animals; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D015195:Drug Design; D015658:HIV Infections / Q000276:immunology* / Q000517:prevention & control; D006801:Humans
D016915:AIDS Vaccines; D019380:Anti-HIV Agents