Diagnosis and management of lung infections.
This article describes contemporary methods of diagnosis and current treatment regimens for most pulmonary infections. Modern techniques used to improve diagnostic yield in pulmonary infection include bronchoscopy, ultrasound- and electromagnetic-guided endoscopy, transthoracic needle biopsy, and samples obtained with thoracoscopy. The spectrum of bacterial, mycobacterial, fungal, and viral pathogens implicated in pulmonary disease is discussed. Treatment strategies and guideline recommendations for antimicrobial selection are described for community-acquired, health care-associated, hospital-acquired, and ventilator-associated pneumonia, and for the most common fungal, mycobacterial, and viral infections. The state-of-the art in topical and aerosolized anti-infective therapy and an algorithm for managing hemoptysis are also presented.
Division of Cardiothoracic Surgery, Department of Surgery, Mayo Clinic, Arizona, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA. jaroszewski.dawn@mayo.edu
Dawn E
DE
Jaroszewski
Brandon J
BJ
Webb
Kevin O
KO
Leslie
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D001999:Bronchoscopy; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D003428:Cross Infection / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D018410:Pneumonia, Bacterial / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D011024:Pneumonia, Viral / Q000188:drug therapy / Q000821:virology
D000900:Anti-Bacterial Agents; D000998:Antiviral Agents