Alkynoate synthesis through the vinylogous reactivity of rhodium(II) carbenoids.
Siloxy group migration: A rhodium(II) carbenoid approach has been developed for the synthesis of alkynoates. This transformation combines the addition of enol ethers at the vinylogous position of β-siloxy-substituted vinyldiazo derivatives with a siloxy group migration to give the products as single diastereomers.
Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, GA 30322, USA.
Damien
D
Valette
Yajing
Y
Lian
John P
JP
Haydek
Kenneth I
KI
Hardcastle
Huw M L
HM
Davies
D000480:Alkynes / Q000138:chemical synthesis*; D002384:Catalysis; D018360:Crystallography, X-Ray; D004952:Esters / Q000737:chemistry*; D004987:Ethers / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
D000480:Alkynes; D004952:Esters; D004987:Ethers; D012238:Rhodium