A swine model to analyze arterial structural changes induced by mechanical thrombectomy.
We report a novel swine model that allows direct visualization of cervical arteries undergoing mechanical thrombectomy. The model also facilitates evaluation of histologic changes observed in the arteries after treatment. Swine superficial cervical arteries, which are similar in size and branching pattern to the human middle cerebral artery, were surgically exposed, occluded with experimental thrombus, and subsequently treated with the Merci clot retriever device. Angiographic and histologic assessment were performed.
Division of Interventional Neuroradiology, Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. iyuki@mednet.ucla.edu
I
I
Yuki
I
I
Kan
A
A
Golshan
J
J
Sohn
Y
Y
Murayama
H V
HV
Vinters
F
F
Viñuela
D000818:Animals; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging* / Q000601:surgery*; D004195:Disease Models, Animal; D006801:Humans; D061185:Mechanical Thrombolysis / Q000295:instrumentation / Q000379:methods*; D058729:Peripheral Arterial Disease / Q000000981:diagnostic imaging* / Q000601:surgery*; D015641:Radiography, Interventional / Q000379:methods; D013552:Swine; D017131:Thrombectomy / Q000295:instrumentation / Q000379:methods*; D013927:Thrombosis / Q000000981:diagnostic imaging* / Q000601:surgery*