Is concurrency driving HIV transmission in sub-Saharan African sexual networks? The significance of sexual partnership typology.
Recently, there has been debate about the role of concurrent partnerships in driving the transmission of HIV, particularly in Southern Africa, where HIV prevalence is up to 25 % in many heterosexual populations and where evidence from sexual behavior surveys also suggests high levels of male concurrency. While mathematical modeling studies have shown that concurrency has the potential to enhance the speed at which HIV spreads in a population, empirical studies up to now have failed to provide conclusive evidence supportive of these effects. Here we discuss some reasons for the apparent discrepancy between theoretical and empirical studies. We propose that studying the impact of concurrency on HIV transmission should be differentiated by taking more insight from social and behavioral studies on sexual partnerships into account. We also suggest that a more rigorous definition is needed for when a factor is considered a driving force for HIV epidemic spread. We illustrate this with a modeling example.
Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, The Netherlands. m.e.e.kretzschmar@umcutrecht.nl
Mirjam
M
Kretzschmar
Michel
M
Caraël
D017954:Africa South of the Sahara / Q000453:epidemiology; D044383:Black People / Q000706:statistics & numerical data; D003466:Cultural Characteristics; D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000635:transmission*; D006801:Humans; D008297:Male; D008433:Mathematics; D008962:Models, Theoretical; D012306:Risk; D012725:Sexual Behavior / Q000208:ethnology*; D012747:Sexual Partners; D012944:Social Support