[Chinese materia medica estrogen-like active substances induce the proliferation and differentiation of the neural stem cells].
Chinese medicine (CM) and Chinese materia medica (CMM) have a long history in treating neurodegenerative diseases. In recent years great progress has taken place in modern pharmacological studies on CMM inducing the proliferation and differentiation of neural stem cells (NSCs). In order to find out the internal correlation between classic CM theories and modern pharmacological achievements, the author raised that the estrogen-like activity of nurturing Gan and Shen CMM is one of CMM's mechanisms for inducing the proliferation and differentiation of NSCs through summarizing the progress of CMM's inducing the proliferation and differentiation of NSCs, taking nurturing Gan and Shen as the starting point, and combining the achievements of estrogen's inducing the proliferation and differentiation of NSCs.
College of Basic Medical Sciences, Shandong University of Traditional Chinese Medicine, Jinan 250355. sunlei@sdutcm.edu.cn
Lei
L
Sun
D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004967:Estrogens / Q000494:pharmacology; D006801:Humans; D058953:Neural Stem Cells / Q000166:cytology* / Q000187:drug effects*
D004365:Drugs, Chinese Herbal; D004967:Estrogens