Fatal anthrax infection in a heroin user from southern Germany, June 2012.
Blood cultures from a heroin user who died in June 2012, a few hours after hospital admission, due to acute septic disease, revealed the presence of Bacillus anthracis. This report describes the extended diagnosis by MALDI-TOF and real-time PCR and rapid confirmation of the anthrax infection through reference laboratories. Physicians and diagnostic laboratories were informed and alerted efficiently through the reporting channels of German public health institutions, which is essential for the prevention of further cases.
Institute of Medical Microbiology and Hygiene, University Hospital of Regensburg, Germany. thomas.holzmann@klinik.uni-regensburg.de
T
T
Holzmann
D
D
Frangoulidis
M
M
Simon
P
P
Noll
S
S
Schmoldt
M
M
Hanczaruk
G
G
Grass
M
M
Pregler
A
A
Sing
S
S
Hörmansdorfer
H
H
Bernard
R
R
Grunow
R
R
Zimmermann
W
W
Schneider-Brachert
A
A
Gessner
U
U
Reischl
D000881:Anthrax / Q000175:diagnosis* / Q000209:etiology*; D001408:Bacillus anthracis / Q000235:genetics / Q000302:isolation & purification*; D016470:Bacteremia / Q000209:etiology*; D004340:Drug Contamination; D055030:Drug Users; D017809:Fatal Outcome; D016680:Genome, Bacterial; D005858:Germany; D003932:Heroin; D006801:Humans; D008297:Male; D008875:Middle Aged; D060888:Real-Time Polymerase Chain Reaction; D018805:Sepsis / Q000209:etiology; D015819:Substance Abuse, Intravenous / Q000150:complications*
D003932:Heroin