Psychoimmune interactions in women of reproductive age with endometriosis.
Psychoimmune interactions were studied in women of reproductive age with endometriosis. Pronounced immunological shifts manifested in a shift of the T-cellular immunity, resulting in imbalanced production of pro- (IL-1β, IL-2, IFN-γ) and anti-inflammatory (IL-4) cytokines. Significant correlations between the severity of mental shifts and immunopathogenetic factors in the studied patient population demonstrated the psychoneuroimmune nature of endometriosis.
Institute of Mental Health, Siberian Division of the Russian Academy of Medical Sciences, Federal Agency for Health Care and Social Development, Tomsk, Russia. nreginaf@rambler.ru
R F
RF
Nasyrova
L S
LS
Sotnikova
N V
NV
Baystrukova
G V
GV
Krivoschchekova
V V
VV
Novitsky
I E
IE
Kupriyanova
V Ya
VY
Semke
I O
IO
Naslednikova
A N
AN
Baykov
D000293:Adolescent; D000328:Adult; D015703:Antigens, CD / Q000378:metabolism; D001007:Anxiety / Q000097:blood / Q000453:epidemiology / Q000276:immunology; D016022:Case-Control Studies; D015897:Comorbidity; D016207:Cytokines / Q000097:blood; D003863:Depression / Q000097:blood / Q000453:epidemiology / Q000276:immunology; D004715:Endometriosis / Q000097:blood / Q000453:epidemiology / Q000276:immunology* / Q000523:psychology*; D005260:Female; D006801:Humans; D018655:Lymphocyte Count; D008214:Lymphocytes / Q000276:immunology / Q000378:metabolism; D008875:Middle Aged; D013315:Stress, Psychological / Q000097:blood / Q000453:epidemiology / Q000276:immunology; D055815:Young Adult
D015703:Antigens, CD; D016207:Cytokines