Mini-laparoscopy in the endoscopy unit.
OBJECTIVE
The evaluation of liver histology is an important component of the diagnosis and staging of liver diseases. The most common technique employed to sample liver tissue for decades has been percutaneous liver biopsy. Although this is a relatively well tolerated technique in the early stages of liver disease, it carries a high risk of complications, particularly hemorrhage, in patients with advanced cirrhosis. Mini-laparoscopy allows macroscopic assessment and biopsy under direct vision and therefore is a well tolerated and effective technique.


RESULTS
The major advantages of this technique are direct visualization of the liver surface, thereby allowing inspection for morphologic changes of cirrhosis as well as targeted biopsies, the ability to immediately treat potential complications (bleeding and bile leakage), furthermore the peritoneal cavity can be visualized to stage gastrointestinal (GI) malignancies. Additionally, 'blind' percutaneous liver biopsy fails to establish a diagnosis in about 25% of cases, largely because of sampling error.


CONCLUSIONS
This technique presents the opportunity to visualize the surface of the liver and the peritoneal cavity, making it a valuable tool for liver biopsy. This review summarizes the technique of mini-laparoscopy and addresses its potential uses and limitations as a diagnostic modality.
I. Med Department, Johannes Gutenberg University of Mainz, Mainz, Germany.
A
A
Hoffman
F
F
Rahman
S
S
Murthy
P R
PR
Galle
Ralf
R
Kiesslich
D000075202:Contraindications; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008107:Liver Diseases / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D010529:Peritoneal Cavity / Q000473:pathology; D010532:Peritoneal Diseases / Q000473:pathology*