[Correlation of surgical timing and prognosis for ruptured intracranial aneurysms].
OBJECTIVE
To explore the correlation between surgical timing and clinical prognosis for ruptured intracranial aneurysms.


METHODS
A series of 187 patients with intracranial aneurysm treated surgically at our department were analyzed retrospectively. Among them, 101 patients received an average follow-up period of 9 months (range: 6 - 14). Timings of operation that might affect the clinical efficacies of microsurgery were analyzed. The modified Rankin scale (mRS) of discharge and the corresponding follow-up mRS were all analyzed.


RESULTS
Timing of operation was negatively correlated with mRS of hospital discharge (P < 0.05), but it had no correlation with follow-up mRS (P > 0.05); patients whose discharge mRS were 1, 2, 3 or 4 had better long-term efficacies (P < 0.05) while those with a discharge mRS of 5 fare worse (P > 0.05).


CONCLUSIONS
The short-term efficacy of early microsurgery for intracranial aneurysms is worse than those of medium and late microsurgery. But no obvious differences exist between the long-term efficacies of early, medium and late microsurgery. The patients whose discharge mRS were 1, 2, 3 or 4 have better long-term efficacies.
Department of Neurosurgery, Second Hospital of Shandong University, Jinan 250033, China.
Yong
Y
Ji
Qing-hu
QH
Meng
Zhen
Z
Xu
Qing-lin
QL
Zhang
Zhi-gang
ZG
Wang
D000328:Adult; D000368:Aged; D017542:Aneurysm, Ruptured / Q000601:surgery*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult