Photoselective vaporization of the prostate with GreenLight HPS 120-W laser for benign prostatic hyperplasia: 36 months' follow-up.
OBJECTIVE
To evaluate the 3-year clinical outcomes and durability of photoselective vaporization of the prostate (PVP) with the GreenLight HPS laser in the treatment of symptomatic and obstructive benign prostatic hyperplasia (BPH).


METHODS
A total of 78 patients underwent PVP with the GreenLight HPS laser from October 2007 to November 2008. The baseline and treatment outcomes after surgery were evaluated 3 years later with the International Prostate Symptom Score (IPSS), quality of life (QoL), maximum flow rate (Q(max)), postvoid residual rate (PVR), and transrectal ultrasound-determined prostate volume. These parameters were assessed at 1, 3, 6, 12, 24, and 36 months.


RESULTS
Patients' urinary symptoms and QoL significantly improved after surgery. The functional outcomes showed immediate and stable improvements during the entire follow-up period. At 36 months, the average percentage of improvements compared with baseline was as follows: IPSS, 60.2%; QoL, 80.9%; Q(max), 138.7%, and PVR, 82.6%. The median prostate volume, evaluated by transrectal ultrasonography, showed a 50.4% reduction when compared to preoperative volume. Overall, complications from surgery were low; only 6.7% of the 75 patients required reoperation during the 3-year follow-up.


CONCLUSIONS
PVP using the GreenLight HPS laser showed a safe and effective treatment outcome for the treatment of symptomatic and obstructive BPH.
Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Yachen
Y
Zang
Boxin
B
Xue
Yuanyuan
Y
Zhang
Dongrong
D
Yang
Jie
J
Gao
Chuanyang
C
Sun
Yong
Y
Cui
Wei
W
Tao
Dong
D
Chen
Yuxi
Y
Shan
D000368:Aged; D000369:Aged, 80 and over; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D007834:Lasers; D008027:Light; D008297:Male; D008875:Middle Aged; D010777:Photochemistry / Q000379:methods; D011467:Prostate / Q000000981:diagnostic imaging / Q000473:pathology / Q000528:radiation effects; D011468:Prostatectomy / Q000379:methods; D011470:Prostatic Hyperplasia / Q000628:therapy*; D011788:Quality of Life; D013997:Time Factors; D016896:Treatment Outcome; D014463:Ultrasonography; D014835:Volatilization