Nanomaterials in complex biological systems: insights from Raman spectroscopy.
The interaction of nanomaterials with biomolecules, cells, and organisms plays an important role in cell biology, toxicology, and nanotechnology. Spontaneous Raman scattering can be used to probe biomolecules, cells, whole animals, and nanomaterials alike, opening interesting avenues to study the interaction of nanoparticles with complex biological systems. In this review we discuss work in biomedical Raman spectroscopy that has either been concerned directly with nanostructures and biosystems, or that indicates important directions for successful future studies on processes associated with nano-bio-interactions.
Humboldt-Universität zu Berlin, Department of Chemistry, Brook-Taylor-Str. 2, 12489 Berlin, Germany.
Daniela
D
Drescher
Janina
J
Kneipp
D000818:Animals; D001695:Biology / Q000379:methods*; D002460:Cell Line; D002477:Cells / Q000166:cytology / Q000378:metabolism; D006801:Humans; D049329:Nanostructures; D013059:Spectrum Analysis, Raman / Q000379:methods*