Pro/con debate: Is etomidate safe in hemodynamically unstable critically ill patients?
Etomidate is an induction agent known for its smooth intubating conditions and cardiovascular stability. Studies, however, have shown that a single dose of etomidate can result in a prolonged adrenal insufficiency. The impact of this in patients with sepsis has been a matter for debate. This review presents a pro/con case for using etomidate in hemodynamically unstable critically ill patients and provides guidance for alternative induction techniques and when the use of etomidate might be justified despite these concerns.
Gordon
G
Flynn
Yahya
Y
Shehabi
D000309:Adrenal Insufficiency / Q000139:chemically induced*; D003422:Critical Care; D016638:Critical Illness; D005045:Etomidate / Q000009:adverse effects*; D006439:Hemodynamics; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects*; D007442:Intubation, Intratracheal; D061214:Patient Safety
D006993:Hypnotics and Sedatives; D005045:Etomidate