Improvement of a compressed inferior vena cava due to IgG4-related retroperitoneal fibrosis with steroid therapy.
A 79-year-old man had a 3.5-year history of edema of the lower extremities of unknown etiology. Abdominal computed tomography showed a soft tissue mass around the abdominal aorta, and the biopsy revealed dense fibrosis with abundant infiltration of IgG4-positive plasma cells. His serum IgG4 level was increased to 188 mg/dL. His lower extremity edema was induced by stenosis of the inferior vena cava (IVC) due to the mass. With a diagnosis of IgG4-related retroperitoneal fibrosis, he was treated with steroid, and the leg edema decreased with improvement of patency of the IVC and reduction of the soft tissue mass.
Department of Internal Medicine, Tokyo Metropolitan Komagome Hospital, Japan.
Mizuki
M
Nishimura
Terumi
T
Kamisawa
Yasuyuki
Y
Kitahara
Akihiro
A
Nishizawa
Taku
T
Tabata
Seiichi
S
Hara
Sawako
S
Kuruma
Kazuro
K
Chiba
Takashi
T
Fujiwara
Go
G
Kuwata
Hideto
H
Egashira
Koichi
K
Koizumi
Junko
J
Fujiwara
Takeo
T
Arakawa
Kumiko
K
Momma
D000368:Aged; D003251:Constriction, Pathologic; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D018810:Magnetic Resonance Angiography; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D012185:Retroperitoneal Fibrosis / Q000188:drug therapy* / Q000276:immunology* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014682:Vena Cava, Inferior / Q000473:pathology
D007074:Immunoglobulin G; D011239:Prednisolone