[Effect of statins on activity of matrix metalloproteases and serum concentration of cystatin C in patients with various risk of development of ischemic heart disease and in patients after coronary artery bypass surgery].
We compared new non-lipid atherosclerosis indexes related to inflammation and macrophage stimulation (serum concentration of cystatin C, matrix metalloproteases and chitotriosidase activity) with common inflammatory (high sensitivity C reactive protein) and lipid markers in elderly persons and patients with atherosclerosis and ischemic heart disease who have undergone coronary bypass surgery.
M S
MS
Cherkanova
T A
TA
Korolenko
I Iu
IIu
Bravve
T P
TP
Gerasimova
D000328:Adult; D015415:Biomarkers; D002097:C-Reactive Protein / Q000378:metabolism; D001026:Coronary Artery Bypass / Q000379:methods*; D003331:Coronary Vessels / Q000378:metabolism / Q000503:physiopathology; D055316:Cystatin C / Q000097:blood*; D005260:Female; D006596:Hexosaminidases / Q000378:metabolism*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage / Q000009:adverse effects / Q000378:metabolism; D007249:Inflammation / Q000188:drug therapy / Q000378:metabolism; D008297:Male; D045726:Metalloproteases / Q000378:metabolism*; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000378:metabolism* / Q000503:physiopathology / Q000628:therapy; D058226:Plaque, Atherosclerotic / Q000188:drug therapy / Q000209:etiology / Q000378:metabolism; D018570:Risk Assessment / Q000379:methods
D015415:Biomarkers; D055316:Cystatin C; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D002097:C-Reactive Protein; D006596:Hexosaminidases; C086400:chitotriosidase; D045726:Metalloproteases