Copper-catalyzed aerobic oxidation of N-substituted hydroxylamines: efficient and practical access to nitroso compounds.
A general and efficient aerobic oxidation of N-substituted hydroxylamines is described. The mild reaction conditions employed provide a catalytic and sustainable alternative to stoichiometric oxidation methods to gain access to a range of nitroso compounds, such as acylnitroso, nitrosoformate, nitrosoformamide, iminonitroso, arylnitroso, and P-nitrosophosphine oxide derivatives in excellent yield.
Department of Chemistry & Biochemistry, University of California , Santa Barbara, California 93106, United States.
Charles P
CP
Frazier
Alejandro
A
Bugarin
Jarred R
JR
Engelking
Javier
J
Read de Alaniz
D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006898:Hydroxylamines / Q000737:chemistry*; D015394:Molecular Structure; D009603:Nitroso Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction
D006898:Hydroxylamines; D009603:Nitroso Compounds; D003300:Copper