Peculiarities of rat serum proteome profile in metabolic stress.
We identified individual proteins characterizing starvation-induced metabolic stress. Sustained changes at the level of proteome caused by metabolic stress were demonstrated. Intensified synthesis of S6 kinase ribosomal protein, immunoglobulin lambda light chains, and inter-alpha-trypsin inhibitor was observed in the experimental groups.
Institute of Nutrition, Russian Academy of Medical Sciences, Moscow, Russia. sharanova.natalia@gmail.com
N E
NE
Sharanova
A V
AV
Vasiliev
M M G
MM
Gapparov
D000510:Alpha-Globulins / Q000235:genetics* / Q000378:metabolism; D000818:Animals; D015180:Electrophoresis, Gel, Two-Dimensional; D015870:Gene Expression; D020869:Gene Expression Profiling; D007146:Immunoglobulin lambda-Chains / Q000235:genetics* / Q000378:metabolism; D008297:Male; D020543:Proteome / Q000235:genetics* / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D019893:Ribosomal Protein S6 Kinases / Q000235:genetics* / Q000378:metabolism; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013217:Starvation / Q000235:genetics / Q000378:metabolism; D013312:Stress, Physiological / Q000235:genetics*
D000510:Alpha-Globulins; D007146:Immunoglobulin lambda-Chains; D020543:Proteome; C011877:inter-alpha-inhibitor; D019893:Ribosomal Protein S6 Kinases