Encapsulation of enzyme in large mesoporous material with small mesoporous windows.
Trypsin has been encapsulated in the mesopores of a hierarchical mesoporous silica material synthesized via Cu(I) catalyzed azide-alkyne click reaction between azide functionalized large spherical SBA-15 particles and alkyne functionalized mesoporous silica nanoparticles (MSNs). Encapsulated trypsin functions as an efficient biocatalyst and can be recycled several times.
CReST Unit, Chemical Engineering Division, National Chemical laboratory, Dr Homi Bhabha Road, Pune, India.
Bharmana
B
Malvi
Sayam Sen
SS
Gupta
D000480:Alkynes / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D002384:Catalysis; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry; D014357:Trypsin / Q000737:chemistry* / Q000378:metabolism
D000480:Alkynes; D001386:Azides; C509969:SBA-15; D012822:Silicon Dioxide; D003300:Copper; D014357:Trypsin