[Prevalence and major risk factors of peripartum thromboembolic disease in different regions of Guangdong province].
OBJECTIVE
To investigate the prevalence and major risk factors of peripartum thromboembolic disease in different regions of Guangdong province.


METHODS
Data from 169 218 pregnant women in different regions of Guangdong province from January 2005 to June 2010 were analyzed retrospectively. The prevalence and epidemiological characteristics of thromboembolic disease during pregnancy or puerperium were investigated.


RESULTS
Of the studied population, (1) 201 cases (1.3‰) suffered from thromboembolic disease during pregnancy or puerperium including 128 cases of deep vein thrombosis (DVT), 68 cases of cerebral venous thrombosis (CVT) and 5 pulmonary embolism, the prevalence rates were 0.8‰, 0.4‰, and 0.02‰ respectively. (2) Risk factors in different regions showed that, in the Pearl River Delta area, the major risk factors for DVT would include previous or family history of thrombosis, pregnancy complications, with medically involved diseases, prolonged bed rest and pregnancy weight gain>15 kg etc. While in eastern, western, northern parts of Guangdong, the major risk factors for DVT would include pregnancy weight gain>15 kg, prolonged bed rest, preeclampsia, cesarean section and complications during pregnancy. In Pearl River Delta region, the major risk factors for CVT would include eclampsia, preeclampsia, pregnancy complications, prolonged bed rest>3 days, past history or family history of thrombosis. While eclampsia, preeclampsia, advanced age or younger age, pregnancy weight gain>15 kg, complications during pregnancy were the major risk factors for CVT in the eastern, western or northern parts of Guangdong.


CONCLUSIONS
Prevalence and major risk factors of peripartum thromboembolic disease in different regions of Guangdong were different. It was crucial to take effective measures in pregnant women with different epidemiological characteristics and risk factors to prevent and reduce the incidence of peripartum thromboembolic disease.
Obstetrics and Gynecology Department of Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Qi-tao
QT
Huang
Mei
M
Zhong
Chen-hong
CH
Wang
Dun-jin
DJ
Chen
Zheng-ping
ZP
Liu
Jing
J
Li
Shuo-shi
SS
Wang
Li-ping
LP
Wang
Tian-rong
TR
Song
Xue-jing
XJ
Guo
Ling-zhi
LZ
Leng
Xiao-hua
XH
Luo
Jian
J
Liu
Jing-xia
JX
Qin
Hai-ying
HY
Liang
Li-na
LN
Liu
D000328:Adult; D005260:Female; D006801:Humans; D058725:Peripartum Period; D011247:Pregnancy; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D020246:Venous Thrombosis / Q000453:epidemiology*; D055815:Young Adult