Brain metastasis from medullary thyroid carcinoma.
The brain is an exceedingly rare site of metastasis in medullary thyroid carcinoma (MTC). A 50-year-old female who had a history of micro-MTC 11 years prior developed a cerebellar metastasis which was incidentally discovered. Imaging revealed a right cerebellar hemispheric mass with contrast enhancement on CT scans. Histopathologic exam demonstrated a metastatic tumour composed of nodules and sheets of large tumour cells with abundant cytoplasm. Immunohistochemistry confirmed the origin from a MTC. This case report highlights the unique features of an unusual metastatic brain tumour, which followed an indolent course for a long time despite multiple distant metastases.
Department of Pathology, Batman Regional State Hospital, Batman, Turkey.
P
P
Börcek
S L
SL
Asa
F
F
Gentili
S
S
Ezzat
T-R
TR
Kiehl
D001932:Brain Neoplasms / Q000556:secondary*; D018276:Carcinoma, Medullary / Q000556:secondary*; D018278:Carcinoma, Neuroendocrine; D005260:Female; D006801:Humans; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000473:pathology*