Highly enantioselective hydrogenation of β,β-disubstituted nitroalkenes.
Building the building blocks: A highly enantioselective hydrogenation of β-aryl-β-alkyl disubstituted nitroalkenes 1 has been developed. This method results in enantiomerically pure nitroalkanes 2, which are versatile precursors for chemical synthesis.
Institute of Pesticide Science and College of Science, Northwest Agriculture & Forestry University, Yangling, Shaanxi 712100, China.
Shengkun
S
Li
Kexuan
K
Huang
Bonan
B
Cao
Jiwen
J
Zhang
Wenjun
W
Wu
Xumu
X
Zhang
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D006865:Hydrogenation; D009595:Nitroparaffins / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D000475:Alkenes; D009595:Nitroparaffins