title: Value of a new post-procedural intravascular ultrasound score in predicting target vessel revascularization after coronary drug-eluting stents implantation.
abstract: OBJECTIVE
  There is no simple or feasible post-procedural intravascular ultrasound (IVUS) score to predict major adverse cardiac events (MACE) in patients undergoing drug-eluting stents (DES) implantation. The aim of this study is to validate a new IVUS score for predicting MACE.
  
  
  METHODS
  A total of 295 patients (with 322 lesions) were enrolled. IVUS score was calculated in each lesion based on five IVUS morphological characteristics: inflow/outflow disease, malapposition, underexpansion, tissue protrusion, and edge dissection (iMUTE score). We assigned two points to an underexpansion and one point for each presence of other factors. Patients were divided into low score (iMUTE score<2, n=137) and high score (iMUTE score≥2, n=158) groups.
  
  
  RESULTS
  At one year follow-up, a trend was seen in favor of the low iMUTE score group in MACE (3.65% vs. 10.10%; P=0.052), and there was more target vessel revascularization (TVR) in the high iMUTE score group compared with low score group (6.96% vs. 1.46%; P=0.044). Low iMUTE score was an independent predictor of freedom from TVR at one year (adjusted hazard ratio (HR) 0.5, 95% confidence interval (CI) 0.1-0.8; P=0.02).
  
  
  CONCLUSIONS
  Post-procedural IVUS iMUTE scoring was simple and feasible in clinical practice, and can provide independent prognostic value for TVR in patients undergoing DES implantation.
authors: Department of Cardiology, Shenyang Northern Hospital, Shenyang 110016, China.
authors: Kai
authors: K
authors: Xu
authors: Ya-ling
authors: YL
authors: Han
authors: Quan-min
authors: QM
authors: Jing
authors: Shou-li
authors: SL
authors: Wang
authors: Ying-yan
authors: YY
authors: Ma
authors: Xiao-zeng
authors: XZ
authors: Wang
authors: Geng
authors: G
authors: Wang
authors: Zu-lu
authors: ZL
authors: Wang
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D002309:Cardiology / Q000379:methods; D017023:Coronary Angiography / Q000379:methods; D003324:Coronary Artery Disease / Q000150:complications* / Q000628:therapy*; D023903:Coronary Restenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016016:Proportional Hazards Models; D012306:Risk; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000379:methods*