title: Transition-metal-free superbase-promoted stereoselective α-vinylation of ketones with arylacetylenes: a general strategy for synthesis of β,γ-unsaturated ketones.
abstract: A wide variety of β,γ-unsaturated ketones of E configuration have been obtained in good to excellent yields via KO(t)Bu/DMSO promoted α-vinylation of aliphatic, cycloaliphatic, and alkyl aromatic (heteroaromatic) ketones with diverse arylacetylenes.
authors: A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, 1 Favorsky Str., 664033 Irkutsk, Russia. boris_trofimov@irioch.irk.ru
authors: Boris A
authors: BA
authors: Trofimov
authors: Elena Yu
authors: EY
authors: Schmidt
authors: Nadezhda V
authors: NV
authors: Zorina
authors: Elena V
authors: EV
authors: Ivanova
authors: Igor' A
authors: IA
authors: Ushakov
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D004121:Dimethyl Sulfoxide / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D007659:Ketones; D004121:Dimethyl Sulfoxide