title: Indole alkaloids from Vinca major and V. minor growing in Turkey.
abstract: A new indole alkaloid, 11-hydroxypolyneuridine, was isolated from Vinca major subsp. major L. and the known indole alkaloids vallesiachotamine and isovallesiachotamine from Vinca minor L. This is the first report on the alkaloids of both Vinca species growing in Turkey; vallesiachotamine and isovallesiachotamine were isolated from a Vinca species for the first time. V. minor may be considered as a new source for these two alkaloids due to their occurrence in high amount in the aerial parts of the plant. The alkaloid extracts of the two Vinca species were found to have high lipid peroxidation inhibitory and DPPH radical scavenging activities. Anticholinesterase activity of the extracts was also very strong.
authors: Department of Chemistry, Faculty of Science and Letters, Istanbul Technical University, 34469 Maslak, Istanbul, Turkey.
authors: Fatemeh
authors: F
authors: Bahadori
authors: Gülaçti
authors: G
authors: Topçu
authors: Mehmet
authors: M
authors: Boğa
authors: Ayla
authors: A
authors: Türkekul
authors: Ufuk
authors: U
authors: Kolak
authors: Murat
authors: M
authors: Kartal
mesh_terms: D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000494:pharmacology; D004789:Enzyme Activation / Q000187:drug effects; D026121:Indole Alkaloids / Q000737:chemistry* / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects; D014421:Turkey; D031053:Vinca / Q000737:chemistry*
chemical_list: D002800:Cholinesterase Inhibitors; D026121:Indole Alkaloids; C518014:polyneuridine; C573958:vallesiachotamine