title: Severe chronic blepharitis and scarring ectropion associated with discoid lupus erythematosus.
abstract: Discoid lupus erythematosus is a common form of chronic cutaneous lupus erythematosus, an autoimmune inflammatory disease that affects most of the human organs, including the skin, kidneys, joints, heart and lungs. We describe a 45-year-old Caucasian woman with a 21-year history of eyelid redness and irritation. She had been treated with antibiotics, steroids and eyelid hygiene, a therapy that resulted to brief periods of relief of symptoms. In the last 12 months, her symptoms seemed to have exacerbated, despite the administration of a local therapy. Following biopsy, a diagnosis of discoid lupus erythematosus was confirmed and the patient was placed on a systemic therapy with hydroxychloroquine. The eyelid inflammation decreased but severe scarring of the marginal eyelids persisted, resulting in cicatricial ectropion.
authors: 2nd Department of Ophthalmology, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors: Nikolaos
authors: N
authors: Kopsachilis
authors: Konstantinos T
authors: KT
authors: Tsaousis
authors: Theofilos
authors: T
authors: Tourtas
authors: Ioannis T
authors: IT
authors: Tsinopoulos
mesh_terms: D001706:Biopsy; D001762:Blepharitis / Q000175:diagnosis / Q000209:etiology*; D002908:Chronic Disease; D002921:Cicatrix / Q000150:complications / Q000473:pathology; D003937:Diagnosis, Differential; D004483:Ectropion / Q000175:diagnosis / Q000209:etiology*; D005143:Eyelids / Q000473:pathology*; D005260:Female; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged; D012720:Severity of Illness Index; D012867:Skin / Q000473:pathology