title: Percutaneous interstitial brachytherapy for adrenal metastasis: technical report.
abstract: We developed and evaluated the feasibility of a brachytherapy technique as a safe and effective treatment for adrenal metastasis. Adapting a paravertebral insertion technique in radiofrequency ablation of adrenal tumors, we developed an interstitial brachytherapy for adrenal metastasis achievable on an outpatient basis. Under local anesthesia and under X-ray CT guidance, brachytherapy applicator needles were percutaneously inserted into the target. A treatment plan was created to eradicate the tumor while preserving normal organs including the spinal cord and kidney. We applied this interstitial brachytherapy technique to two patients: one who developed adrenal metastasis as the third recurrence of uterine cervical cancer after reirradiation, and one who developed metachronous multiple metastases from malignant melanoma. The whole procedure was completed in 2.5 hours. There were no procedure-related or radiation-related early/late complications. FDG PET-CT images at two and three months after treatment showed absence of FDG uptake, and no recurrence of the adrenal tumor was observed for over seven months until expiration, and for six months until the present, respectively. This interventional interstitial brachytherapy procedure may be useful as a safe and eradicative treatment for adrenal metastasis.
authors: Department of Radiation Oncology, Wakayama Medical University, Wakayama City, 641-8510 Japan. kazushi.kishi@gmail.com
authors: Kazushi
authors: K
authors: Kishi
authors: Shinji
authors: S
authors: Tamura
authors: Yasushi
authors: Y
authors: Mabuchi
authors: Tetsuo
authors: T
authors: Sonomura
authors: Yasutaka
authors: Y
authors: Noda
authors: Motoki
authors: M
authors: Nakai
authors: Morio
authors: M
authors: Sato
authors: Kazuhiko
authors: K
authors: Ino
authors: Noboru
authors: N
authors: Yamanaka
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000556:secondary*; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy / Q000379:methods*; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000556:secondary; D005260:Female; D006801:Humans; D008545:Melanoma / Q000532:radiotherapy / Q000556:secondary; D008875:Middle Aged; D010610:Pharyngeal Neoplasms; D049268:Positron-Emission Tomography; D011880:Radiotherapy Planning, Computer-Assisted; D002583:Uterine Cervical Neoplasms