title: A case of carcinomatous meningitis despite prophylactic cranial irradiation in small cell lung cancer during treatment with amrubicin.
abstract: A 47-year-old man was diagnosed with limited-disease small cell lung cancer. Treatment was initiated with concurrent chemotherapy and radiotherapy. A partial response was achieved, and prophylactic cranial irradiation (PCI) was administered. Local recurrence was identified on follow-up and treated with amrubicin (AMR). After two courses of AMR, a state of stable disease was achieved and AMR treatment was continued. After the third course of AMR, the patient was urgently hospitalized suffering from a headache and disturbance of consciousness, and a diagnosis of carcinomatous meningitis was made. This case report concerns a case of carcinomatous meningitis despite PCI during treatment with AMR.
authors: Department of Medical Oncology and Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
authors: Tetsuya
authors: T
authors: Oguri
authors: Takehiro
authors: T
authors: Uemura
authors: Eiji
authors: E
authors: Kunii
authors: Hiroaki
authors: H
authors: Ozasa
authors: Hirotsugu
authors: H
authors: Ohkubo
authors: Mikinori
authors: M
authors: Miyazaki
authors: Ken
authors: K
authors: Maeno
authors: Shigeki
authors: S
authors: Sato