title: Facile Synthesis of Mutagen X (MX): 3-Chloro-4-(dichloromethyl)-5-hydroxy-5H-furan-2-one.
abstract: 3-Chloro-4-(dichloromethyl)-5-hydroxy-5H-furan-2-one (Mutagen X, MX) was synthesized in six steps from commercially-available and inexpensive starting materials (27% overall yield). This synthesis enables the preparation of MX analogs and does not require the use of chlorine gas, as do previously reported methods.
authors: Fox Chase Chemical Diversity Center, Inc., 3805 Old Easton Road, Doylestown, PA 18902, USA.
authors: Venkata
authors: V
authors: Velvadapu
authors: Mark E
authors: ME
authors: McDonnell
authors: Eileen K
authors: EK
authors: Jaffe
authors: Allen B
authors: AB
authors: Reitz