title: A copper(I)-catalyzed reaction of 2-(2-ethynylphenyl)oxirane, sulfonyl azide, with 2-isocyanoacetate.
abstract: A novel and straightforward synthetic protocol for the efficient construction of 3',5'-dihydro-1H-spiro[benzo[d]oxepine-2,4'-imidazoles] through a copper(I)-catalyzed reaction between 2-(2-ethynylphenyl)oxirane, sulfonyl azide, and 2-isocyanoacetate is described.
authors: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.
authors: Shaoyu
authors: S
authors: Li
authors: Jie
authors: J
authors: Wu
mesh_terms: D000085:Acetates / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D005027:Ethylene Oxide / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D013450:Sulfones / Q000737:chemistry*
chemical_list: C576706:2-(2-ethynylphenyl)oxirane; D000085:Acetates; D001386:Azides; D007477:Ions; D013450:Sulfones; D003300:Copper; D005027:Ethylene Oxide; C007170:cyanoacetic acid