title: [Novel concepts in biology of diffuse endocrine system: results and future investigations].
abstract: Diffuse endocrine system is a largest part of endocrine system of vertebrates. Recend findings showed that DES-cells are not neuroectodermal but have ectodermal, mesodermal, and entodermal ontogeny. The article reviews novel concept of diffuse endocrine system anatomy and physiology, functional role of DES hormones and poorly investigated aspects like DES-cell morphology, hormones secretion in normal and pathologic conditions. Further research of diffuse endocrine system has a great significance for biochemistry, morphology, and clinical medicine.
authors: V V
authors: VV
authors: Iaglov
authors: N V
authors: NV
authors: Iaglova
mesh_terms: D000818:Animals; D004475:Ectoderm; D004703:Endocrine System / Q000166:cytology / Q000196:embryology / Q000502:physiology*; D006728:Hormones / Q000378:metabolism; D008648:Mesoderm
chemical_list: D006728:Hormones