title: Epidemiology of Streptococcus pneumoniae.
abstract: The epidemiology of S. pneumoniae invasive infections in France, over the last few years, was modified by two public health measures. A nationwide campaign for the rationalization of antibiotic prescription was implemented in 2001 and vaccination of young children with the pneumococcal 7-valent conjugate vaccine in 2003. These measures led to a decrease in antibiotic resistance in S. pneumoniae strains, a lower incidence of invasive infections due to vaccine serotypes, but a higher incidence of infections due to non-vaccine serotypes, especially 7F and 19A. Despite the replacement, the incidence of invasive pneumococcal infections in children less than 2 years of age remains lower than it was before introducing the 7-valent conjugate vaccine.
authors: Laboratoire de microbiologie, hôpital Européen Georges-Pompidou, 20, rue Leblanc, 75908 Paris cedex 15, France. emmanuelle.varon@egp.aphp.fr
authors: E
authors: E
authors: Varon
mesh_terms: D024881:Drug Resistance, Bacterial; D005602:France / Q000453:epidemiology; D006801:Humans; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000517:prevention & control; D022242:Pneumococcal Vaccines; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification / Q000187:drug effects
chemical_list: D022242:Pneumococcal Vaccines