title: Ca2+-dependent transcriptional control of Ca2+ homeostasis.
abstract: Intracellular free Ca(2+) ions regulate many cellular functions, and in turn, the cell devotes many genes/proteins to keep tight control of the level of intracellular free Ca(2+). Here, we review recent work on Ca(2+)-dependent mechanisms and effectors that regulate the transcription of genes encoding proteins involved in the maintenance of the homeostasis of Ca(2+) in the cell.
authors: National Center of Biotechnology, Consejo Superior de Investigaciones Científicas (CSIC) and the Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), 28049 Madrid, Spain. naranjo@cnb.csic.es
authors: Jose R
authors: JR
authors: Naranjo
authors: Britt
authors: B
authors: Mellström
mesh_terms: D017398:Alternative Splicing; D000818:Animals; D019703:Calcineurin / Q000378:metabolism; D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000378:metabolism; D002540:Cerebral Cortex / Q000378:metabolism; D005786:Gene Expression Regulation; D006706:Homeostasis; D006801:Humans; D053496:Inositol 1,4,5-Trisphosphate Receptors / Q000378:metabolism; D007477:Ions; D051605:Kv Channel-Interacting Proteins / Q000378:metabolism*; D051379:Mice; D008954:Models, Biological; D016133:Polymerase Chain Reaction / Q000379:methods; D012097:Repressor Proteins / Q000378:metabolism*; D015398:Signal Transduction; D014158:Transcription, Genetic
chemical_list: D015220:Calcium Channels; D053496:Inositol 1,4,5-Trisphosphate Receptors; D007477:Ions; C496749:KCNIP3 protein, human; D051605:Kv Channel-Interacting Proteins; D012097:Repressor Proteins; D019703:Calcineurin; D002118:Calcium