title: Anatomical and functional evaluation of tympanoplasty using a transitory natural latex biomembrane implant from the rubber tree Hevea brasiliensis.
abstract: OBJECTIVE
  To compare the role of transitory latex and sylastic® implants in tympanoplasty on the closure of tympanic perforations.
  
  
  METHODS
  A randomized double-blind prospective study was conducted on 107 patients with chronic otitis media submitted to underlay tympanoplasty and divided at random into three groups: control with no transitory implant, latex membrane group, and sylastic® membrane group.
  
  
  RESULTS
  Greater graft vascularization occurred in the latex membrane group (p<0.05). Good biocompatibility was obtained with the use of the latex and silicone implants, with no effect on the occurrence of infection, otorrhea or otorragy.
  
  
  CONCLUSIONS
  The use of a transitory latex implant induced greater graft vascularization, with a biocompatible interaction with the tissue of the human tympanic membrane.
authors: Department of Oftalmology, Otorrhinolaryngology and Head Neck Surgery, Faculty of Medicine of Ribeirao Preto, USP, São Paulo, SP, Brazil.
authors: Marcos Miranda
authors: MM
authors: Araujo
authors: Eduardo Tanaka
authors: ET
authors: Massuda
authors: Miguel Angelo
authors: MA
authors: Hyppolito
mesh_terms: D000293:Adolescent; D000328:Adult; D001672:Biocompatible Materials / Q000627:therapeutic use*; D002648:Child; D004311:Double-Blind Method; D005260:Female; D028482:Hevea; D006801:Humans; D007840:Latex / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D019736:Prostheses and Implants; D012828:Silicones / Q000627:therapeutic use; D016896:Treatment Outcome; D014432:Tympanic Membrane / Q000601:surgery*; D014433:Tympanoplasty / Q000379:methods*; D014945:Wound Healing; D055815:Young Adult
chemical_list: D001672:Biocompatible Materials; D007840:Latex; D012828:Silicones