title: Incidence of genital infection among patients with type 2 diabetes in the UK General Practice Research Database.
abstract: The objective of this population-based study was to evaluate the incidence of vaginitis (females) and balanitis (males) among a cohort of type 2 diabetes patients and compare this risk to patients without diabetes. The study population included 125,237 female patients and 146,603 males identified from GPRD. All patients were followed for 1-year from their study index date for the first record of an infection or a censored event. Among patients with diabetes the incidence of vaginitis was 21.0/1000PY (95% CI 19.8-22.1) with the risk being 1.81 (95% CI 1.64-2.00) greater that patients without diabetes. The incidence of balanitis among diabetes patients was 8.4/1000PY (95% CI 7.8-9.1) with a relative risk of 2.85 (2.39-3.39) compared to patients without diabetes. Additional analyses were performed by HbA1c level. Results from this large population-based study indicate that patients with diabetes are at an increased risk of being diagnosed with infections of the genital tract and patients with poorly controlled diabetes have higher risks.
authors: Bristol-Myers Squibb Co., USA. ishan.hirji@bms.com
authors: Ishan
authors: I
authors: Hirji
authors: Susan W
authors: SW
authors: Andersson
authors: Zhenchao
authors: Z
authors: Guo
authors: Niklas
authors: N
authors: Hammar
authors: Andres
authors: A
authors: Gomez-Caminero
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001446:Balanitis / Q000097:blood / Q000150:complications / Q000453:epidemiology* / Q000382:microbiology; D015331:Cohort Studies; D016208:Databases, Factual; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications* / Q000382:microbiology / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D058006:General Practice; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D015994:Incidence; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D060737:Reproductive Tract Infections / Q000097:blood / Q000150:complications / Q000453:epidemiology* / Q000382:microbiology; D012307:Risk Factors; D006113:United Kingdom / Q000453:epidemiology; D014627:Vaginitis / Q000097:blood / Q000150:complications / Q000453:epidemiology* / Q000382:microbiology; D055815:Young Adult
chemical_list: D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human