title: Helicobacter pylori CagA tertiary structure reveals functional insights.
abstract: CagA is a major disease-associated factor injected by the gastric pathogen Helicobacter pylori. In this issue, Hayashi et al. (2012) report the crystallographic structure of the CagA N terminus (residues 24-876) at 3.19 Å resolution. This study revealed three distinct domains, giving novel insights into intramolecular and intermolecular protein and phosphatidylserine interactions.
authors: University College Dublin, School of Medicine and Medical Science, Science Center West, Belfield Campus, Ireland. Steffen.Backert@ucd.ie
authors: Steffen
authors: S
authors: Backert
authors: Nicole
authors: N
authors: Tegtmeyer