title: Combination of core biopsy and fine-needle aspiration increases diagnostic rate for small solid renal tumors.
abstract: OBJECTIVE
  Our aim was to evaluate the performance of combination of fine-needle aspiration (FNA) and core biopsy (CB) as a method for the diagnosis of small solid renal tumors.
  
  
  METHODS
  Ninety patients with a radiologically detected small solid renal tumor (≤ 4 cm) underwent a biopsy. Patient underwent FNA (FNA group, n=32) or CB (CB group, n=30) or combination of both FNA and CB (combination group, n=28). The diagnostic rate and accuracy of both techniques were assessed.
  
  
  RESULTS
  The diagnostic rate of the combination group (92.9%) was superior to that of the FNA group (62.5%) and CB group (76.7%) (p=0.006, and p=0.147, respectively). In the combination group, 11 CBs were diagnostic with 13 nondiagnostic FNAs, while 4 FNAs were diagnostic with 6 nondiagnostic CBs. For tumors ≤ 2 cm, the combination of FNA and CB significantly increased the diagnostic rate, compared with FNA alone (p=0.033) and CB alone (p=0.044). The accuracy for FNA, CB and the combination of FNA and CB was 88%, 100% and 100%, respectively.
  
  
  CONCLUSIONS
  The combination of FNA and CB increased the diagnostic rate of renal biopsy for the small solid renal tumors.
authors: Department of Urology, North Hospital, CHU of Saint Etienne, 42055 Saint-Etienne cedex 2, France.
authors: Guorong
authors: G
authors: Li
authors: Muriel
authors: M
authors: Cuilleron
authors: An
authors: A
authors: Zhao
authors: Frédéric
authors: F
authors: Obadia
authors: Pascal
authors: P
authors: Mouracade
authors: Jacques
authors: J
authors: Tostain
authors: Michèle
authors: M
authors: Cottier
authors: Michel
authors: M
authors: Peoc'h
authors: Marc
authors: M
authors: Gigante
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged