title: [The influence of lectin isoforms of Bacillus subtilis saprophytic strain IMV B-7014 on viability of normal and cancer cells in vitro].
abstract: Structural and functional polymorphism of saprophytic bacterium lectin was demonstrated to be due to subunit organization of the molecule as it was shown for many lectins of plant and animal origin. Three isoforms of extracellular sialic acid-specific lectin produced by Bacillus subtilis saprophytic strain IMV B-7014 were discovered that differed for physicochemical and biological properties. The influence of the lectin isoforms on mammalian cells proliferation and morphology in vitro depends both on the subunit organization of the protein molecule and the type of cells under study.
authors: V S
authors: VS
authors: Pidhors'kyĭ
authors: E O
authors: EO
authors: Kovalenko
authors: I S
authors: IS
authors: Karpova
authors: O V
authors: OV
authors: Sashchuk
authors: K I
authors: KI
authors: Get'man
authors: T O
authors: TO
authors: Ruban
authors: O M
authors: OM
authors: Sukhorada
authors: L L
authors: LL
authors: Lukash
mesh_terms: D000818:Animals; D001412:Bacillus subtilis / Q000502:physiology*; D016466:CHO Cells; D002470:Cell Survival / Q000187:drug effects; D006224:Cricetinae; D003470:Culture Media; D005347:Fibroblasts / Q000187:drug effects; D020387:Food Chain; D006367:HeLa Cells; D006386:Hemagglutination Tests; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007525:Isoelectric Focusing; D037102:Lectins / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D051379:Mice; D008970:Molecular Weight; D020033:Protein Isoforms / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology
chemical_list: D003470:Culture Media; D037102:Lectins; D020033:Protein Isoforms