title: Ruthenium amino carboxylate complexes as asymmetric hydrogen transfer catalysts.
abstract: The synthesis and characterization of optically active amino carboxylate complexes of formula [(η(6)-arene)Ru(Aa)Cl] (arene = C(6)H(6), C(6)Me(6), Aa = amino carboxylate) as well as those of the related trimers [{(η(6)-arene)Ru(Aa)}(3)][BF(4)](3) are reported. Trimerization takes place with chiral self-recognition: only diastereomers equally configured at the metal, R(Ru)R(Ru)R(Ru) or S(Ru)S(Ru)S(Ru), are detected. The crystal structures of the complexes [(η(6)-C(6)H(6))Ru(Pip)Cl] and [{(η(6)-C(6)Me(6))Ru(Pro)}(3)][BF(4)](3) have been determined by X-ray diffraction methods. Both types of complexes catalyse the hydrogen transfer reaction from 2-propanol to ketones with moderate enantioselectivity (up to 68% ee). The enantiodifferentiation achieved can be accounted for by assuming that Noyori's bifunctional mechanism is operating.
authors: Instituto de Síntesis Química y Catálisis Homogénea (ISQCH), CSIC-Universidad de Zaragoza, Departamento de Química Inorgánica, Zaragoza, Spain. dcarmona@unizar.es
authors: Daniel
authors: D
authors: Carmona
authors: Fernando
authors: F
authors: Viguri
authors: M
authors: M
authors: Pilar Lamata
authors: Joaquina
authors: J
authors: Ferrer
authors: Elisa
authors: E
authors: Bardají
authors: Fernando J
authors: FJ
authors: Lahoz
authors: Pilar
authors: P
authors: García-Orduña
authors: Luis A
authors: LA
authors: Oro
mesh_terms: D019840:2-Propanol / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006859:Hydrogen / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry; D008968:Molecular Conformation; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D002264:Carboxylic Acids; D056831:Coordination Complexes; D007659:Ketones; D012428:Ruthenium; D006859:Hydrogen; D019840:2-Propanol