title: [Genetic and environmental contribution to rheumatoid arthritis: a family study].
abstract: We report on the HLA typing of three brothers (A, B, C) with rheumatoid arthritis (RA) and their six sons. This family is interesting for the full concordance for RA between parents. The aim of this study was the discovery of genetic and/or enviromental cofactors determining this absolute concordance.
authors: Unità Operativa Complessa Medicina, Azienda ospedaliera San Giovanni Addolorata, Rome. filippo.iebba@virgilio.it
authors: Filippo
authors: F
authors: Iebba
authors: Fiorella
authors: F
authors: Di Sora
authors: Wilma
authors: W
authors: Leti
authors: Tatiana
authors: T
authors: Montella
authors: Francesco
authors: F
authors: Montella
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000209:etiology / Q000235:genetics*; D001194:Asbestos; D004781:Environmental Exposure; D005260:Female; D005805:Genes, MHC Class I; D005802:Genes, MHC Class II; D020022:Genetic Predisposition to Disease; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D008297:Male; D008947:Mixed Connective Tissue Disease / Q000235:genetics; D012307:Risk Factors; D012737:Sex Factors; D035781:Siblings; D012859:Sjogren's Syndrome / Q000235:genetics; D014028:Tobacco Smoke Pollution
chemical_list: D006680:HLA Antigens; D014028:Tobacco Smoke Pollution; D001194:Asbestos