title: Early spondyloarthritis.
abstract: Spondyloarthritis (SpA) is a large family of chronic inflammatory diseases characterized by inflammation of the axial skeleton, a typically asymmetric peripheral arthritis of the lower limbs, enthesitis, typical extra-articular manifestations, and shared genetic background. The prevalence in the general population is up to 2% for the entire group. SpA, particularly ankylosing spondylitis, has been associated with a diagnostic delay of up to 10 years. Important efforts toward shortening this delay have been made, including the development of new classification criteria. This article discusses the current concept of the disease, typical manifestations, advances in diagnosis, and current treatment recommendations.
authors: Rheumatology, Medical Department I, Campus Benjamin Franklin, Charité Universitätsmedizin Berlin, Hindenburgdamm 30, Berlin 12203, Germany.
authors: Denis
authors: D
authors: Poddubnyy
authors: Martin
authors: M
authors: Rudwaleit
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D057210:Delayed Diagnosis; D042241:Early Diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D012446:Sacroiliac Joint / Q000473:pathology; D013131:Spine / Q000473:pathology; D025241:Spondylarthritis / Q000145:classification / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D013167:Spondylitis, Ankylosing / Q000175:diagnosis
chemical_list: D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents