title: Congenital ascites due to hepatoblastoma with extensive peritoneal implantation metastases in a premature equine fetus.
abstract: A premature dead equine fetus with excessive fluctuating distension of the abdomen was delivered by extraction. Post-mortem examination revealed ascites and a solitary, irregular, bulging, multinodular, firm, yellow mass of 25 cm in diameter in the right liver lobe. Extensive peritoneal implantation metastases were present. The masses were composed of polygonal embryonal cells arranged in sheets and nests. Based on the immunohistochemical expression of Ki67, low molecular weight cytokeratin and alpha-1 fetoprotein, a diagnosis of hepatoblastoma with peritoneal implantation metastases was made.
authors: Department of Pathology, Bacteriology and Avian Diseases, College of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke Ghent, Belgium. cynthia.devries@ugent.be
authors: C
authors: C
authors: de Vries
authors: E
authors: E
authors: Vanhaesebrouck
authors: J
authors: J
authors: Govaere
authors: M
authors: M
authors: Hoogewijs
authors: L
authors: L
authors: Bosseler
authors: K
authors: K
authors: Chiers
authors: R
authors: R
authors: Ducatelle
mesh_terms: D000818:Animals; D001201:Ascites / Q000151:congenital / Q000175:diagnosis / Q000662:veterinary*; D001344:Autopsy / Q000662:veterinary; D014408:Biomarkers, Tumor / Q000378:metabolism; D005260:Female; D005333:Fetus / Q000378:metabolism; D018197:Hepatoblastoma / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D006734:Horse Diseases / Q000151:congenital* / Q000175:diagnosis* / Q000378:metabolism; D006736:Horses; D007633:Keratins / Q000378:metabolism; D008113:Liver Neoplasms / Q000150:complications / Q000175:diagnosis / Q000662:veterinary*; D010534:Peritoneal Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000662:veterinary*; D011247:Pregnancy; D047928:Premature Birth / Q000662:veterinary; D000509:alpha-Fetoproteins / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D000509:alpha-Fetoproteins; D007633:Keratins