title: [National and regional market penetration rates of generic's high dosage buprenorphine: its evolution from 2006 to 2008, using reimbursed drug database].
abstract: OBJECTIVE
  To assess the national market penetration rate (PR) of generic high-dosage buprenorphine (HDB) in 2008 and its evolution since their marketing (2006), and making a point for each dosage and at regional level.
  
  
  METHODS
  Retrospective study over data using national and regional health reimbursement database over three years (2006-2008).
  
  
  RESULTS
  In 2008, the generic HDB's national MPR was 31%. The PR for each dosage were 45% for 0.4 mg, 36% for 2 mg and 19% for 8 mg. The (PR) based on Defined Daily Dose (DDD) was 23% in 2008, 15% in 2007 and 4% in 2006. In 2008, at the regional level, disparities were observed in the adjusted penetration rate from 15% in Île de France to 39% in Champagne Ardennes Lorraine.
  
  
  CONCLUSIONS
  The national PR of generic HDB has increased. There are differences in MPR in terms of dosage and area. However, this PR is still low (in 2008, 82% of the delivered drugs are generics).
authors: Direction Régionale du Service Médical de la région Provence-Alpes-Côte d'Azur et Corse (CNAMTS), Marseille, France.
authors: Christelle
authors: C
authors: Boczek
authors: Elisabeth
authors: E
authors: Frauger
authors: Joëlle
authors: J
authors: Micallef
authors: Véronique
authors: V
authors: Allaria-Lapierre
authors: Patrick
authors: P
authors: Reggio
authors: Vincent
authors: V
authors: Sciortino
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000191:economics; D002047:Buprenorphine / Q000008:administration & dosage / Q000191:economics; D016208:Databases, Factual; D062313:Databases, Pharmaceutical; D004363:Drug Utilization / Q000639:trends; D016568:Drugs, Generic; D005602:France / Q000453:epidemiology; D006801:Humans; D007349:Insurance, Health, Reimbursement / Q000191:economics / Q000706:statistics & numerical data; D012189:Retrospective Studies
chemical_list: D000701:Analgesics, Opioid; D016568:Drugs, Generic; D002047:Buprenorphine