title: Preparation of the β-cyclodextrin-vitamin C (β-CD-Vc) inclusion complex under high hydrostatic pressure (HHP).
abstract: In this study, a novel high hydrostatic pressure (HHP) technique was used to prepare the β-cyclodextrin-vitamin C (β-CD-Vc) inclusion complex. The inclusion ratio was positively correlated with the pressure under 300 MPa and remained at above 50.0% when the pressure was more than 300 MPa. Fourier-transform infrared spectroscopy (FI-IR) and UV-visible spectroscopy (UV-vis) analysis showed that characteristic absorption bands and the absorption peak of Vc disappeared in the spectra of the β-CD-Vc inclusion complex. Furthermore, differential scanning calorimetry (DSC) data revealed that only one endothermic peak appeared at about 138 °C in the DSC curve of the β-CD-Vc inclusion complex. These results indicate that the HHP treatment effectively induces the formation of β-CD-Vc inclusion complex.
authors: The State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, 1800 Lihu Road, Wuxi 214122, China.
authors: Xiuting
authors: X
authors: Hu
authors: Benxi
authors: B
authors: Wei
authors: Hongyan
authors: H
authors: Li
authors: Chunsen
authors: C
authors: Wu
authors: Yuxiang
authors: Y
authors: Bai
authors: Xueming
authors: X
authors: Xu
authors: Zhengyu
authors: Z
authors: Jin
authors: Yaoqi
authors: Y
authors: Tian
mesh_terms: D000975:Antioxidants / Q000008:administration & dosage / Q000737:chemistry; D001205:Ascorbic Acid / Q000008:administration & dosage* / Q000737:chemistry; D002152:Calorimetry, Differential Scanning; D004337:Drug Carriers / Q000138:chemical synthesis / Q000737:chemistry; D004345:Drug Industry / Q000379:methods; D006874:Hydrostatic Pressure; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction; D047392:beta-Cyclodextrins / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D004337:Drug Carriers; D011108:Polymers; D047392:beta-Cyclodextrins; D001205:Ascorbic Acid