title: Concurrent pleural infiltration by chronic lymphocytic leukemia and adenocarcinoma of unknown primary site diagnosed by effusion cytology.
abstract: Synchronous malignancies in a pleural effusion are rare. A case of concurrent pleural infiltration by adenocarcinoma of unknown primary site and chronic lymphocytic leukemia (CLL) is presented in this case study, which was diagnosed by effusion cytology. Pleural effusion is not an uncommon complication in patients with B-CLL. Even in a pleural effusion rich in monoclonal lymphocytes, the presence of a second cancer must be excluded because this can be the main cause of mortality. The role of cytology in such cases is of paramount importance.
authors: Second Department of Internal Medicine, Medical School, Attikon University General Hospital, Athens, Greece.
authors: Ioannis
authors: I
authors: Vrettos
authors: Konstantinos
authors: K
authors: Kamposioras
authors: Stamatios
authors: S
authors: Peridis
authors: Dionisios
authors: D
authors: Aninos
authors: Stella
authors: S
authors: Kazika
authors: Aris
authors: A
authors: Spathis
authors: Petros
authors: P
authors: Karakitsos
authors: Angelos
authors: A
authors: Papadopoulos
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D017809:Fatal Outcome; D005434:Flow Cytometry; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000473:pathology*; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology*; D009382:Neoplasms, Unknown Primary / Q000473:pathology*; D016066:Pleural Effusion, Malignant / Q000473:pathology*