title: Follicular dendritic cell sarcoma: a diagnostic challenge !
abstract: Follicular dendritic cell sarcoma (FDCS) is a spindle cell neoplasm of histiocytic-dendritic cells origin. It is known to occur in lymph nodes and rarely has been reported in extranodal tissues like head and neck, mediastinum and gastrointestinal tract. We herein report the first FDCS arising from anal canal in a 56-year-old man. The tumor was composed of bland short spindle cells in focal whorl formation with interspersed few lymphocytes. The tumor cells were classically positive for CD21, CD23, CD35 and vimentin. Despite its misleading morphology, immunohistochemistry helped us to reach a conclusive diagnosis for relevant therapy.
authors: Department of Pathology, AFMC, Pune, India. drajaymalik@gmail.com
authors: Ajay
authors: A
authors: Malik
authors: Ajit
authors: A
authors: Veniyoor
authors: Barnard
authors: B
authors: Fanthome
authors: Vibha
authors: V
authors: Dutta
mesh_terms: D015703:Antigens, CD / Q000378:metabolism; D001005:Anus Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D054740:Dendritic Cell Sarcoma, Follicular / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D015703:Antigens, CD