title: [Pityriasis rubra pilaris].
abstract: Pityriasis rubra pilaris is an inflammatory papulosquamous skin disease of unknown etiology. Incidence rates vary between 1:5,000-1:50,000. Six subtypes are differentiated on clinical background. The juvenile circumscribed subtype has best prognosis. Generalized disease impairs quality of life of patients. It is associated with various complications and comorbidities. Treatment of pityriasis rubra pilaris is challenging. Retinoids are first line drugs. In recalcitrant cases, tumor necrosis factor-α inhibitors have been used successfully.
authors: Klinik für Dermatologie und Allergologie, Krankenhaus Dresden-Friedrichstadt, Städtisches Klinikum, Akademisches Lehrkrankenhaus der TU Dresden, Friedrichstr. 41, 01067 Dresden. wollina-uw@khdf.de
authors: U
authors: U
authors: Wollina
mesh_terms: D003879:Dermatologic Agents / Q000627:therapeutic use*; D006801:Humans; D010916:Pityriasis Rubra Pilaris / Q000175:diagnosis* / Q000188:drug therapy*; D012176:Retinoids / Q000627:therapeutic use*
chemical_list: D003879:Dermatologic Agents; D012176:Retinoids