title: Mitochondrial genome variability within the Candida parapsilosis species complex.
abstract: Candida parapsilosis species complex includes three closely related species, namely C. parapsilosis (sensu stricto), C. orthopsilosis, and C. metapsilosis. Unlike most other yeast lineages, members of this species complex possess a linear mitochondrial genome. Yet, its circularized mutant form was identified in strains of C. orthopsilosis and C. metapsilosis. To investigate the underlying variability, we performed comparative analyses of the complete mitochondrial DNA sequences in a collection of strains. Our results demonstrate that in contrast to C. parapsilosis and C. metapsilosis, C. orthopsilosis exhibits remarkably high nucleotide diversity whose pattern is consistent with intraspecific genetic exchange.
authors: Department of Biochemistry, Faculty of Natural Sciences, Comenius University, Mlynska dolina CH-1, 842 15 Bratislava, Slovak Republic. matus.a.valach@gmail.com
authors: Matus
authors: M
authors: Valach
authors: Leszek P
authors: LP
authors: Pryszcz
authors: Lubomir
authors: L
authors: Tomaska
authors: Attila
authors: A
authors: Gacser
authors: Toni
authors: T
authors: Gabaldón
authors: Jozef
authors: J
authors: Nosek
mesh_terms: D002175:Candida / Q000145:classification* / Q000235:genetics*; D004270:DNA, Circular / Q000235:genetics; D004272:DNA, Mitochondrial / Q000235:genetics*; D022761:Gene Transfer, Horizontal; D014644:Genetic Variation; D054629:Genome, Mitochondrial
chemical_list: D004270:DNA, Circular; D004272:DNA, Mitochondrial