title: Superoxide scavenging activity of plastoquinone derivative 10-(6'-plastoquinonyl)decyltriphenylphosphonium (SkQ1).
abstract: The plastoquinone derivative 10-(6'-plastoquinonyl)decyltriphenylphosphonium (SkQ1) has the ability to scavenge superoxide anion radical. This ability is manifested both in vitro and in vivo in experiments with the bacterium Escherichia coli. The protective effect of SkQ1 in vivo significantly exceeds that of ascorbic acid.
authors: Rostov State Medical University, Pereulok Nakhichevanskii 29, Rostov-on-Don, 344022, Russia. vladimirchi@yandex.ru
authors: V A
authors: VA
authors: Chistyakov
authors: E V
authors: EV
authors: Prazdnova
authors: L V
authors: LV
authors: Gutnikova
authors: M A
authors: MA
authors: Sazykina
authors: I S
authors: IS
authors: Sazykin
mesh_terms: D001205:Ascorbic Acid / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D016166:Free Radical Scavengers / Q000378:metabolism / Q000494:pharmacology*; D010971:Plastoquinone / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D013481:Superoxides / Q000378:metabolism / Q000494:pharmacology*
chemical_list: C532038:10-(6'-plastoquinonyl)decyltriphenylphosphonium; D016166:Free Radical Scavengers; D013481:Superoxides; D010971:Plastoquinone; D001205:Ascorbic Acid