title: Controlled ring-opening polymerization of substituted episulfides for side-chain functional polysulfide-based amphiphiles.
abstract: We used initiation solutions of DBU and different thiols for the controlled ring-opening homo- and copolymerization of ethoxy ethyl thio glycidyl ether (EETGE) and allyl thio glycidyl ether (ATGE) to side-chain multifunctional polysulfides. Optimized preparation conditions allow the syntheses of monomodal homopolysulfides and monomodal polysulfide-block-mPEG copolymers. Furthermore, copolymers of EETGE and mPEG are firstly synthesized, characterized, and finally deprotected to yield intact poly(thio glycidol)-block-poly(ethylene glycol) copolymers. These amphiphiles are suitable to form particles in aqueous solutions as confirmed by DLS and cryo-SEM measurements.
authors: Department and Chair for Functional Materials in Medicine and Dentistry, University of Würzburg, 97070 Würzburg, Germany.
authors: Matthias
authors: M
authors: Kuhlmann
authors: Smriti
authors: S
authors: Singh
authors: Jürgen
authors: J
authors: Groll
mesh_terms: D004852:Epoxy Compounds / Q000737:chemistry; D011092:Polyethylene Glycols / Q000737:chemistry; D058105:Polymerization; D013440:Sulfides / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D004852:Epoxy Compounds; D013440:Sulfides; C020344:glycidyl ethers; D014867:Water; D011092:Polyethylene Glycols; C032915:polysulfide