title: Five-year follow-up of participants in a randomised controlled trial showing benefits from exercise for breast cancer survivors during adjuvant treatment. Are there lasting effects?
abstract: OBJECTIVE
  In an earlier randomised controlled trial, we showed that early stage breast cancer patients who received a supervised exercise programme, with discussion of behaviour change techniques, had psychological and functional benefits 6 months after the intervention. The purpose of this study was to determine if benefits observed at 6 months persisted 18 and 60 months later.
  
  
  METHODS
  Women who were in the original trial were contacted at 18 and 60 months after intervention. Original measures were repeated.
  
  
  RESULTS
  Of the 148 women from the original study who agreed to be contacted again, 114 attended for follow-up at 18 months and 87 at 60 months. Women in the original intervention group reported more leisure time physical activity and more positive moods at 60 months than women in the original control group. Irrespective of original group allocation, women who were more active consistently reported lower levels of depression and increased quality of life compared to those who were less active.
  
  
  CONCLUSIONS
  We have shown that there are lasting benefits to an exercise intervention delivered during treatment to breast cancer survivors. Regular activity should be encouraged for women with early stage breast cancer as this can have lasting implications for physical and psychological functioning.
authors: School of Psychological Sciences and Health, University of Strathclyde, 76 Southbrae Drive, Glasgow G13 1PP, UK. nanette.mutrie@ed.ac.uk
authors: Nanette
authors: N
authors: Mutrie
authors: Anna
authors: A
authors: Campbell
authors: Sarah
authors: S
authors: Barry
authors: Kate
authors: K
authors: Hefferon
authors: Alex
authors: A
authors: McConnachie
authors: Diana
authors: D
authors: Ritchie
authors: Sian
authors: S
authors: Tovey
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000401:mortality / Q000523:psychology / Q000628:therapy*; D002277:Carcinoma / Q000401:mortality / Q000523:psychology / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D015444:Exercise / Q000502:physiology*; D005081:Exercise Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008408:Mastectomy; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D010358:Patient Participation; D011788:Quality of Life; D018714:Radiotherapy, Adjuvant; D016032:Randomized Controlled Trials as Topic / Q000379:methods; D012606:Scotland; D017741:Survivors / Q000523:psychology / Q000706:statistics & numerical data; D013997:Time Factors; D016896:Treatment Outcome