title: Increased risk of placenta previa is associated with endometriosis and tubal factor infertility in assisted reproductive technology pregnancy.
abstract: Although assisted reproductive technology (ART) is suspected to increase the risk of placenta previa, a life-threatening complication of pregnancy, the reason is poorly understood. We recruited consecutive 318 pregnancies conceived by ART in our clinic and examined relation of ten variables, i.e. maternal age, gravidity, parity, male or female fetus, previous abortion, previous cesarean delivery, endometriosis, ovulatory disorder, tubal disease, and male infertility, to placenta previa, by logistic regression analysis. As a result, we found that endometriosis (odds ratio = 15.1; 95% CI = 7.6-500.0) and tubal disease (odds ratio = 4.4; 95% CI = 1.1-26.3) were significantly associated with placenta previa. It would be preferable to take the increased risk of placenta previa into account in treating ART pregnancy with endometriosis and tubal disease.
authors: Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, Bunkyo, Tokyo, Japan.
authors: Yuri
authors: Y
authors: Takemura
authors: Yutaka
authors: Y
authors: Osuga
authors: Akihisa
authors: A
authors: Fujimoto
authors: Nagisa
authors: N
authors: Oi
authors: Ryo
authors: R
authors: Tsutsumi
authors: Minako
authors: M
authors: Koizumi
authors: Tetsu
authors: T
authors: Yano
authors: Yuji
authors: Y
authors: Taketani
mesh_terms: D000328:Adult; D004715:Endometriosis / Q000503:physiopathology*; D005184:Fallopian Tube Diseases / Q000503:physiopathology*; D005191:Family Characteristics; D005260:Female; D005307:Fertilization in Vitro / Q000009:adverse effects; D005500:Follow-Up Studies; D006785:Hospitals, University; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D007248:Infertility, Male / Q000503:physiopathology; D007564:Japan / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D010923:Placenta Previa / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*; D011247:Pregnancy; D012189:Retrospective Studies; D012307:Risk Factors; D020554:Sperm Injections, Intracytoplasmic / Q000009:adverse effects; D016216:Ultrasonography, Prenatal