title: Acute spill-mimicking exposure effect of hexavalent chromium on the pituitary-ovarian axis of a teleost, Channa punctatus (Bloch).
abstract: Acute exposure to hexavalent chromium (as 10, 20, and 40 mg/L potassium dichromate for 96 h) adversely affected the pituitary-ovarian axis of a teleost Channa punctatus. The toxic impact of metal exposure on fish ovary was revealed in the form of increased percentage of atretic follicles, significantly in 20 mg/L and 40 mg/L exposure groups. The follicular atresia mostly occurred in vitellogenic (stage II and stage III) oocytes. Reduction of serum level of 17β-estradiol was also significant in 20 mg/L and 40 mg/L exposure groups. The increase of LH-immunointensity of pituitary gonadotrophs (LHβ-immunoreactive cells) and their hypertrophy was evident, significantly in fish of 40 mg/L exposed group. Thus, the present acute metal spill-mimicking laboratory study clearly demonstrated that short-term exposures to high doses of hexavalent chromium may disrupt reproduction of the fish and affect their population.
authors: Department of Zoology, University of Allahabad, Allahabad 211002, India.
authors: Ashish K
authors: AK
authors: Mishra
authors: Banalata
authors: B
authors: Mohanty
mesh_terms: D000818:Animals; D002857:Chromium / Q000633:toxicity*; D004958:Estradiol / Q000097:blood; D005260:Female; D005399:Fishes / Q000033:anatomy & histology* / Q000502:physiology; D052681:Gonadotrophs / Q000187:drug effects / Q000473:pathology; D007194:India; D009865:Oocytes / Q000187:drug effects / Q000473:pathology; D010053:Ovary / Q000187:drug effects* / Q000473:pathology; D010902:Pituitary Gland / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D011192:Potassium Dichromate / Q000633:toxicity; D012098:Reproduction / Q000187:drug effects; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D014874:Water Pollutants, Chemical; D002857:Chromium; C074702:chromium hexavalent ion; D004958:Estradiol; D011192:Potassium Dichromate