title: Self-reported prior lung diseases as risk factors for non-small cell lung cancer in Mexican Americans.
abstract: This study was conducted to assess the association between prior history of respiratory disease and lung cancer among Mexican Americans using data from a multi-racial/ethnic lung cancer case-control study. Cases (n = 204) were patients with previously untreated lung cancer. Healthy control participants (n = 325) were recruited from a large physician group practice. Demographics, cigarette use, and history of respiratory disease were collected. Multivariable logistic regression models were used to estimate relative risk. Prior history of COPD (OR = 2.0; 95 % CI 1.2-3.3) and pneumonia (OR = 2.2; 95 % CI 1.3-3.6) were associated with an increased risk of lung cancer. These findings illustrate that prior COPD and pneumonia are associated with an increased risk of lung cancer among Mexican Americans. To our knowledge, this is one of largest case-control analyses assessing the role of respiratory disease and lung cancer risk specifically among Mexican-Americans.
authors: Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
authors: Michelle K
authors: MK
authors: McHugh
authors: Matthew B
authors: MB
authors: Schabath
authors: Chung-Han
authors: CH
authors: Ho
authors: Mei
authors: M
authors: Liu
authors: Anthony M
authors: AM
authors: D'Amelio
authors: Anthony J
authors: AJ
authors: Greisinger
authors: George L
authors: GL
authors: Delclos
authors: Margaret R
authors: MR
authors: Spitz
authors: Carol J
authors: CJ
authors: Etzel
mesh_terms: D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000209:etiology*; D016022:Case-Control Studies; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000150:complications*; D008175:Lung Neoplasms / Q000209:etiology*; D008297:Male; D017058:Mexican Americans; D008875:Middle Aged; D016017:Odds Ratio; D011014:Pneumonia / Q000150:complications; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications; D006255:Rhinitis, Allergic, Seasonal / Q000150:complications; D012307:Risk Factors; D057566:Self Report; D012907:Smoking / Q000009:adverse effects; D013781:Texas / Q000453:epidemiology