title: The prognostic value of an increased mean platelet volume and platelet distribution width in the early phase of cerebral venous sinus thrombosis.
abstract: In this study, we aimed to investigate the value of mean platelet volume (MPV), platelet distribution width (PDW) and platelet count in cerebral venous sinus thrombosis (CVST) patients and in control subjects. Fifty-three patients with evidence of CVST and thirty-five controls with similar baseline characteristics were included in the study. CVST patients were further divided into two subgroups based on the presence or absence of parenchymal lesions in cranial MRI. Our analyses revealed a significant difference in MPV and PDW values between CVST patients with lesions and controls (P < 0.05). MPV and PDW values were significantly increased in CVST patients with brain parenchmal lesions, suggesting that MPV and PDW values can be used to predict the severity of CVST.
authors: Department of Neurology, Inonu University School of Medicine, Malatya, Turkey. okamisli@yahoo.com
authors: Ozden
authors: O
authors: Kamisli
authors: Suat
authors: S
authors: Kamisli
authors: Yuksel
authors: Y
authors: Kablan
authors: Sinan
authors: S
authors: Gonullu
authors: Cemal
authors: C
authors: Ozcan
mesh_terms: D001792:Blood Platelets; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010976:Platelet Count; D011859:Radiography; D012851:Sinus Thrombosis, Intracranial / Q000097:blood* / Q000000981:diagnostic imaging / Q000503:physiopathology*