title: Gastrointestinal stromal tumour of the rectum: a report of two cases.
abstract: Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the gastrointestinal tract in adults, although rectal localisation of these tumours is very rare. We report here two cases of rectal stromal tumours in a 77-year-old woman and a 65-year-old man, confirmed by histology and immunohistochemistry. Surgery for rectal GIST patients is the standard treatment and adjuvant imatinib, a tyrosine kinase inhibitor, is indicated for GISTs with a high risk of malignancy, as well as in the case of metastatic or unresectable tumours.
authors: Service d'Oncologie-Radiothérapie, Centre Hospitalier Universitaire Ibn Rochd, 1 quartier des hôpitaux, 20360 Casablanca, Marocco.
authors: Tarik
authors: T
authors: Chekrine
authors: Hassan
authors: H
authors: Jouhadi
authors: Zineb
authors: Z
authors: Bouchbika
authors: Nadia
authors: N
authors: Benchakroun
authors: Nezha
authors: N
authors: Tawfiq
authors: Souha
authors: S
authors: Sahraoui
authors: Abdelatif
authors: A
authors: Benider
mesh_terms: D000368:Aged; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis; D006801:Humans; D008297:Male; D012004:Rectal Neoplasms / Q000175:diagnosis