title: Can we safely avoid fasting before abortions with low-dose procedural sedation? A retrospective cohort chart review of anesthesia-related complications in 47,748 abortions.
abstract: BACKGROUND
  Some licensing authorities require fasting before abortions under intravenous sedation to avoid aspiration of gastric contents. This study was conducted to estimate the incidence of anesthesia-related complications in women undergoing abortions without preprocedure fasting.
  
  
  METHODS
  This is a retrospective cohort chart review of patients having abortions with both fentanyl and midazolam at two urban free-standing abortion clinics with routine policy of advising women to eat a light meal before the procedure.
  
  
  RESULTS
  There were no reports of anesthesia-related complications in the 47,748 charts reviewed from 1998 to 2010. Applying Hanley's formula for rare events that have not occurred, the upper 95% confidence interval for the true incidence of anesthesia-related complications for women having abortion under low-dose procedural sedation without fasting was estimated to be 0.00006%.
  
  
  CONCLUSIONS
  This large retrospective cohort chart review identified no complications related to low-dose procedural sedation in over 47,000 consecutive nonfasting patients having abortions through 18 weeks' gestation. Eliminating the requirement to fast would decrease unnecessary stress and unpleasant symptoms without increase in the anesthesia-related complications for women having abortions.
authors: Department of Family Medicine, University of British Columbia, Vancouver, BC, Canada. ellenwiebe@gmail.com
authors: Ellen R
authors: ER
authors: Wiebe
authors: Beata
authors: B
authors: Byczko
authors: Janusz
authors: J
authors: Kaczorowski
authors: Amanda Lea
authors: AL
authors: McLane
mesh_terms: D000028:Abortion, Induced / Q000009:adverse effects*; D000293:Adolescent; D000328:Adult; D018686:Anesthetics, Intravenous / Q000009:adverse effects; D002648:Child; D016001:Confidence Intervals; D016292:Procedural Sedation / Q000009:adverse effects* / Q000379:methods; D005215:Fasting; D005260:Female; D005283:Fentanyl / Q000009:adverse effects; D005865:Gestational Age; D006801:Humans; D008874:Midazolam / Q000009:adverse effects; D008875:Middle Aged; D011247:Pregnancy; D053120:Respiratory Aspiration / Q000139:chemically induced; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D018686:Anesthetics, Intravenous; D008874:Midazolam; D005283:Fentanyl