title: Advances in the synthesis of calystegines and related products and their biochemical properties.
abstract: The revision of the structures and properties of Calystegines shows that they can be regarded as carbohydrate mimics, with related biological activities and peculiar characteristics. Not only they can be isolated from food plants, but they can be obtained from a variety of monosaccharide derivatives and of non-carbohydrate products. Although several synthetic calystegine analogs have been reported as glycosidase inhibitors, new, more potent and effective inhibitors are required.
authors: Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Málaga, 29071 Málaga, Spain. pino@uma.es
authors: M S
authors: MS
authors: Pino-Gonzalez
authors: N
authors: N
authors: Oña
authors: A
authors: A
authors: Romero-Carrasco
mesh_terms: D000818:Animals; D040761:Biomimetic Materials / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D002241:Carbohydrates / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D010936:Plant Extracts / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D010944:Plants / Q000737:chemistry*; D014326:Tropanes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D002241:Carbohydrates; D004791:Enzyme Inhibitors; D010936:Plant Extracts; D014326:Tropanes; C055033:calystegin; D006026:Glycoside Hydrolases