title: Further evidence of reliability and validity of the Huntington's disease quality of life battery for carers: Italian and French translations.
abstract: BACKGROUND
  Existing research suggests that family caregivers of persons with Huntington's disease (HD) face a distinct series of problems, linked to the complex nature of the disease. Aubeeluck and Buchanan (Clin Genet, 71(5):434-445, 2007) developed and validated a disease-specific measure used to explore caregivers quality of life and assess the efficacy of therapeutic interventions. This current study builds on this research through the validation of French and Italian translations of the Huntington's disease quality of life battery for carers (HDQoL-C).
  
  
  METHODS
  A total of 301 family carers completed the HDQoL-C. Participants were recruited through the "Euro-HDB" study which is measuring the burden in HD across Europe and the USA.
  
  
  RESULTS
  Factor analysis demonstrated good internal consistency, reliability and congruent validity. Carers who cared for patients with less clinically severe symptoms reported significantly better QoL than carers of patients with more clinically severe symptoms.
  
  
  CONCLUSIONS
  Findings indicate the HDQoL-C is multi-lingual, multi-cultural and easily applicable in other languages.
authors: Division of Nursing, School of Nursing, Midwifery and Physiotherapy, University of Nottingham, Royal Derby Hospital, Uttoxeter Road , Derby, DE22 3DT, UK. aimee.aubeeluck@nottingham.ac.uk
authors: Aimee
authors: A
authors: Aubeeluck
authors: Julie
authors: J
authors: Dorey
authors: Ferdinando
authors: F
authors: Squitieri
authors: Emilie
authors: E
authors: Clay
authors: Edward J N
authors: EJ
authors: Stupple
authors: Annunziata
authors: A
authors: De Nicola
authors: Heather
authors: H
authors: Buchanan
authors: Tiziana
authors: T
authors: Martino
authors: Mondher
authors: M
authors: Toumi
mesh_terms: D000328:Adult; D000368:Aged; D017028:Caregivers / Q000523:psychology*; D005163:Factor Analysis, Statistical; D005190:Family; D005260:Female; D005602:France; D006801:Humans; D006816:Huntington Disease / Q000523:psychology*; D007558:Italy; D008297:Male; D008875:Middle Aged; D011594:Psychometrics / Q000706:statistics & numerical data; D011788:Quality of Life / Q000523:psychology*; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires / Q000592:standards*; D014177:Translations