title: A nitroolefin functionalized BODIPY chemodosimeter for biothiols driven by an unexpected conjugated addition mechanism.
abstract: A weakly fluorescent nitroolefin functionalized BODIPY 1 was prepared and rapidly reacted with thiols through an unexpected conjugated addition to the azafulvene ring of BODIPY to generate highly fluorescent BODIPYs 4 and 5. This reaction was applied for the highly selective and sensitive detection of Cys in living cells.
authors: Laboratory of Functional Molecular Solids, Ministry of Education, College of Chemistry and Materials Science, Anhui Normal University, Wuhu, China 241000.
authors: Min
authors: M
authors: Zhang
authors: Yangchun
authors: Y
authors: Wu
authors: Shengzhou
authors: S
authors: Zhang
authors: Hongnian
authors: H
authors: Zhu
authors: Qiong
authors: Q
authors: Wu
authors: Lijuan
authors: L
authors: Jiao
authors: Erhong
authors: E
authors: Hao
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001896:Boron Compounds / Q000737:chemistry*; D045744:Cell Line, Tumor; D003545:Cysteine / Q000032:analysis; D005456:Fluorescent Dyes / Q000737:chemistry; D006801:Humans; D008856:Microscopy, Fluorescence; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D000475:Alkenes; D001896:Boron Compounds; D005456:Fluorescent Dyes; D013438:Sulfhydryl Compounds; D003545:Cysteine