title: Growing prevalence of Providencia stuartii associated with the increased usage of colistin at a tertiary health care center.
abstract: From 2005 to 2009, at Detroit Medical Center, the prevalence of Providencia stuartii increased from 0.52 to 0.91/1000 patient-days (p<0.001). The use of colistin also increased (p<0.001) during the study period. The increase in the prevalence of P. stuartii was associated with an increased use of colistin (p<0.001). Facilities that frequently use colistin and tigecycline should closely monitor the prevalence of P. stuartii along with other Proteeae, since these organisms are intrinsically resistant to colistin and tigecycline.
authors: Division of Infectious Diseases, Detroit Medical Center, Wayne State University, 5 Hudson, Harper University Hospital, 3990 John R Street, Detroit, MI 48201, USA. kayokohayakawa@gmail.com
authors: Kayoko
authors: K
authors: Hayakawa
authors: Dror
authors: D
authors: Marchaim
authors: George W
authors: GW
authors: Divine
authors: Jason M
authors: JM
authors: Pogue
authors: Sarwan
authors: S
authors: Kumar
authors: Paul
authors: P
authors: Lephart
authors: Ken
authors: K
authors: Risko
authors: Jack D
authors: JD
authors: Sobel
authors: Keith S
authors: KS
authors: Kaye
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000009:adverse effects; D003091:Colistin / Q000008:administration & dosage* / Q000009:adverse effects; D024901:Drug Resistance, Multiple, Bacterial; D004756:Enterobacteriaceae Infections / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008824:Michigan / Q000453:epidemiology; D008875:Middle Aged; D008911:Minocycline / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives; D015995:Prevalence; D011532:Providencia / Q000302:isolation & purification*; D012189:Retrospective Studies; D062606:Tertiary Care Centers; D000078304:Tigecycline
chemical_list: D000900:Anti-Bacterial Agents; D000078304:Tigecycline; D008911:Minocycline; D003091:Colistin