title: Acute-phase proteins in pregnant Sudanese women with severe Plasmodium falciparum malaria.
abstract: A case-control study was carried out in Kassala and Medani Maternity Hospitals in Sudan to investigate acute-phase proteins [haptoglobin, C-reactive protein (CRP), ferritin and albumin] in three groups of pregnant women (32 in each arm) comprising those with severe Plasmodium falciparum malaria or uncomplicated P. falciparum malaria and healthy controls. Whilst there was no significant difference in the levels of albumin and haptoglobin, ferritin and CRP levels were significantly higher in pregnant women with severe P. falciparum malaria. There were significant positive correlations between parasite count and haptoglobin, and medium positive correlations between parasite count and CRP.
authors: Faculty of Medicine, University of Khartoum, P.O. Box 102, Khartoum, Sudan.
authors: Alfarazdeg A
authors: AA
authors: Saad
authors: Omar E
authors: OE
authors: Mohamed
authors: Abdelaziem A
authors: AA
authors: Ali
authors: Ahmed M
authors: AM
authors: Bashir
authors: Naji I
authors: NI
authors: Ali
authors: Mustafa I
authors: MI
authors: Elbashir
authors: Ishag
authors: I
authors: Adam
mesh_terms: D000209:Acute-Phase Proteins / Q000378:metabolism*; D000328:Adult; D002097:C-Reactive Protein / Q000378:metabolism; D016022:Case-Control Studies; D005260:Female; D005293:Ferritins / Q000097:blood; D006242:Haptoglobins / Q000378:metabolism; D006801:Humans; D016778:Malaria, Falciparum / Q000097:blood* / Q000453:epidemiology; D010963:Plasmodium falciparum / Q000472:pathogenicity*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood* / Q000453:epidemiology; D013397:Sudan / Q000453:epidemiology; D011795:Surveys and Questionnaires
chemical_list: D000209:Acute-Phase Proteins; D006242:Haptoglobins; D002097:C-Reactive Protein; D005293:Ferritins