title: Biocatalytic conversion of lignocellulose to platform chemicals.
abstract: Naturally occurring lignocellulose can be used as a renewable resource for the sustainable production of platform chemicals that can in turn be converted to valuable fine chemicals, polymers, and fuels. The biocatalytic conversion of lignocellulose is a very promising approach due to its high selectivity, mild conditions, and low exergy loss. However, such biocatalytic processes are still seldom applied at the industrial scale since the single conversion steps (pretreatment, hydrolysis, and fermentation) may exhibit low conversion rates, low efficiencies, or high costs. The biocatalytic conversion of lignocellulose to platform chemicals is reviewed in this work. Structures and production rates of lignocellulose are described, and platform chemicals that may be produced from lignocellulose are summarized. Biocatalytic conversion of lignocellulose is distinguished from conventional non-selective approaches. All essential conversion steps used in biocatalytic approaches (pretreatment, hydrolysis, and fermentation) are reviewed in detail. Finally, potential interactions between these conversion steps are highlighted and the advantages as well as disadvantages of integrated process configurations are elucidated. In conclusion, a comprehensive understanding of the biocatalytic conversion of lignocellulose is provided in this review.
authors: AVT-Aachener Verfahrenstechnik, Biochemical Engineering, RWTH Aachen University, Germany.
authors: Gernot
authors: G
authors: Jäger
authors: Jochen
authors: J
authors: Büchs
mesh_terms: D055162:Biocatalysis; D057005:Bioengineering; D001709:Biotechnology / Q000379:methods*; D005285:Fermentation; D006868:Hydrolysis; D008031:Lignin / Q000737:chemistry* / Q000378:metabolism; D009930:Organic Chemicals / Q000737:chemistry* / Q000378:metabolism
chemical_list: D009930:Organic Chemicals; C036909:lignocellulose; D008031:Lignin