title: Harnessing the natural regenerative potential of the dental pulp.
abstract: Biological solutions for the repair and regeneration of the dental tissues offer significant potential for improved clinical treatment outcomes. Translation of dental tissue-engineering approaches to the clinic will make considerable contributions to these outcomes in the future, but exploiting the natural regenerative potential of dentin-pulp to enhance wound-healing responses offers solutions for maintaining pulp vitality now. Strategies to harness the natural regenerative potential of the pulp must be based on a sound biological understanding of the cellular and molecular events taking place, and require careful consideration of the interplay of infection, inflammation, and regeneration.
authors: School of Dentistry, University of Birmingham, St Chads Queensway, Birmingham B4 6NN, UK. a.j.smith@bham.ac.uk
authors: Anthony J
authors: AJ
authors: Smith
authors: James G
authors: JG
authors: Smith
authors: Richard M
authors: RM
authors: Shelton
authors: Paul R
authors: PR
authors: Cooper
mesh_terms: D003782:Dental Pulp / Q000502:physiology*; D003804:Dentin / Q000502:physiology*; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D012038:Regeneration / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology; D013234:Stem Cells / Q000502:physiology; D023822:Tissue Engineering / Q000379:methods*; D014945:Wound Healing / Q000276:immunology / Q000502:physiology*