title: Bioprospecting metagenomics for new glycoside hydrolases.
abstract: To efficiently deconstruct recalcitrant plant biomass to fermentable sugars in industrial processes, biocatalysts of higher performance and lower cost are required. The genetic diversity found in the metagenomes of natural microbial biomass decay communities may harbor such enzymes. The aim of this chapter is to describe strategies, based on metagenomic approaches, for the discovery of glycoside hydrolases (GHases) from microbial biomass decay communities, especially those from unknown or never-been-cultivated microorganisms.
authors: Department of Ecology & Evolution, University of Chicago, Chicago, IL, USA.
authors: Jack
authors: J
authors: Gilbert
authors: Luen-Luen
authors: LL
authors: Li
authors: Safiyh
authors: S
authors: Taghavi
authors: Sean M
authors: SM
authors: McCorkle
authors: Susannah
authors: S
authors: Tringe
authors: Daniel
authors: D
authors: van der Lelie
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D018533:Biomass; D003001:Cloning, Molecular; D057225:Data Mining / Q000379:methods*; D030541:Databases, Genetic; D014644:Genetic Variation; D006026:Glycoside Hydrolases / Q000235:genetics*; D056186:Metagenomics / Q000379:methods*; D016366:Open Reading Frames / Q000235:genetics; D012336:RNA, Ribosomal, 16S / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D012336:RNA, Ribosomal, 16S; D006026:Glycoside Hydrolases