title: 'Idiopathic' acute myocardial infarction in a young patient with noncompaction cardiomyopathy.
abstract: Isolated left ventricular noncompaction (LVNC) is a rare hereditary cardiomyopathy characterized by prominent intraventricular trabeculations separated by deep intertrabecular recessus. While cardiac ischemia due to microvascular dysfunction is common in these patients, ST-segment elevation myocardial infarction (STEMI) is rare and usually seen as a consequence of coincidental coronary artery disease. We report the case of a 20 year-old male patient admitted to our emergency department with a complaint of squeezing chest pain who was subsequently diagnosed with STEMI according to electrocardiographic findings, although an emergent coronary angiogram demonstrated normal coronary arteries. Echocardiography revealed isolated LVNC, and the diagnosis was confirmed via magnetic resonance imaging. Repeat coronary catheterization with acetylcholine infusion and coronary flow reserve measurement failed to demonstrate vasospasm or microvascular dysfunction. As no apparent cause was found, this case was designated 'idiopathic' myocardial infarction. Coronary thromboembolism due to stagnation of blood in the left ventricular cavity remained as the most probable mechanism underlying myocardial infarction.
authors: Department of Cardiology, Kafkas University School of Medicine, Kars, Turkey. TSGuvenc@gmail.com
authors: Tolga Sinan
authors: TS
authors: Güvenç
authors: Hatice Betül
authors: HB
authors: Erer
authors: Servet
authors: S
authors: Altay
authors: Erkan
authors: E
authors: Ilhan
authors: Nurten
authors: N
authors: Sayar
authors: Mehmet
authors: M
authors: Eren
mesh_terms: D006328:Cardiac Catheterization; D002317:Cardiovascular Agents / Q000627:therapeutic use; D017023:Coronary Angiography; D003326:Coronary Circulation; D025401:Echocardiography, Stress; D004562:Electrocardiography; D006801:Humans; D056830:Isolated Noncompaction of the Ventricular Myocardium / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008833:Microcirculation; D017566:Microvascular Angina / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D009203:Myocardial Infarction / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D013923:Thromboembolism / Q000209:etiology; D055815:Young Adult
chemical_list: D002317:Cardiovascular Agents