title: Bottom-up optimization of SERS hot-spots.
abstract: The bottom-up optimization of signal-to-noise ratios for SERS tags employing SAMSA fluorescein as the reporter was achieved using a bifunctional linker with low Raman cross section. By holding the nanoparticles at subnanometer separation, the linker allowed us to optimize the hot-spot thereby significantly reducing the fluorescence background.
authors: Department of Materials Science and Engineering, Institute for Advanced Materials Devices and Nanotechnology, Rutgers, The State University of New Jersey, 607 Taylor Road, Piscataway, New Jersey 08854, USA. lfabris@rci.rutgers.edu
authors: Laura
authors: L
authors: Fabris
mesh_terms: D000588:Amines / Q000737:chemistry; D019281:Dimerization; D053768:Metal Nanoparticles / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013499:Surface Properties
chemical_list: D000588:Amines; D012834:Silver