title: The sleeve gastrectomy intervention to treat morbid obesity in a Parkinson's disease patient.
abstract: OBJECTIVE
  Some Parkinson's disease patients may develop morbid obesity, on account of the reduction in exercise and/or of the appearance of compulsive food intake in the first years after diagnosis. The prescription of central appetite suppressants is actually not recommended in Parkinson's disease patients. To the best of our knowledge, no cases of morbidly obese Parkinson's disease patients submitted to bariatric surgery procedures have been reported in literature before.
  
  
  METHODS
  We here describe for the first time the outcome of a sleeve gastrectomy intervention in a morbidly obese Parkinson's disease patient, resistant to several non-surgical weight-loss treatments.
  
  
  RESULTS
  The outcome of the sleeve gastrectomy intervention was satisfactory in terms of body weight-loss, long term weight stabilization and improvement of cardioprotective circulating factors, including adiponectin. Furthermore, the antiparkinson therapy (levodopa) was reduced by 25%.
  
  
  CONCLUSIONS
  These observations suggest that morbidly obese Parkinson's disease patients, who are resistant to other dietary treatments, might be candidated for sleeve gastrectomy.
authors: Parkinson Institute, Istituti Clinici di Perfezionamento, via Bignami 1, 20126 Milan, Italy.
authors: Michela
authors: M
authors: Barichella
authors: Erica
authors: E
authors: Cassani
authors: Raffaella
authors: R
authors: Cancello
authors: Anna
authors: A
authors: Zecchinelli
authors: Giuseppe
authors: G
authors: Faillace
authors: Gabriella
authors: G
authors: Moise
authors: Alessandra
authors: A
authors: Zulian
authors: Giulia
authors: G
authors: Privitera
authors: Gianni
authors: G
authors: Pezzoli
mesh_terms: D050110:Bariatric Surgery; D015992:Body Mass Index; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008875:Middle Aged; D009767:Obesity, Morbid / Q000601:surgery*; D010300:Parkinson Disease / Q000188:drug therapy / Q000601:surgery*; D016896:Treatment Outcome; D015431:Weight Loss
chemical_list: D007980:Levodopa