title: Pulmonary Mycobacterium kyorinense disease showed clinical improvement following combined therapy with clarithromycin and levofloxacin.
abstract: A 63-year-old man with a past history of resection of pulmonary adenocarcinoma and COPD visited our hospital because of fever, cough and purulent sputum. Chest CT showed an infiltration shadow with multiple bullae in the right lung. There was a slight elevation of the inflammatory response. We established a definitive diagnosis by frequent isolation of Mycobacterium kyorinense on a sputum culture test of acid-fast bacilli. Clarithromycin and levofloxacin were administered after identification of M. kyorinense using a 16S rRNA gene sequence. Subsequently his symptoms improved following combined therapy with clarithromycin and levofloxacin.
authors: Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Japan. yoshihiro@med.kawasaki-m.ac.jp
authors: Yoshihiro
authors: Y
authors: Kobashi
authors: Keiji
authors: K
authors: Mouri
authors: Yasushi
authors: Y
authors: Obase
authors: Shigeki
authors: S
authors: Kato
authors: Mikio
authors: M
authors: Oka
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D017291:Clarithromycin / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D006801:Humans; D064704:Levofloxacin; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy* / Q000382:microbiology; D009170:Nontuberculous Mycobacteria / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification; D015242:Ofloxacin / Q000008:administration & dosage*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D064704:Levofloxacin; D015242:Ofloxacin; D017291:Clarithromycin