title: Incidence and risk factors of irritable bowel syndrome in community subjects with culture-proven bacterial gastroenteritis.
abstract: OBJECTIVE
  The aim of this study was to investigate the incidence and risk factors of irritable bowel syndrome (IBS) in community subjects with culture-proven bacterial gastroenteritis.
  
  
  METHODS
  This was a prospective, community-based, cohort study, which followed patients with a recent history of culture-proven bacterial gastroenteritis. IBS was diagnosed with the use of the Rome II criteria at 3 and 6 months after bacterial dysentery.
  
  
  RESULTS
  Sixty five cases were included and completed the 6 month follow-up. Thirty four cases (52.3%) were female. Salmonella was the pathogen most frequently identified and seen in 41 patients (63.1%). The cumulative incidence of IBS among patients with microbiologically proven bacterial gastroenteritis within a community was 9.2% and 12.3% at 3 and 6 months of follow-up, respectively. The duration of initial diarrhea (≥ 7 days) was associated with an increased risk for the development of IBS (aOR, 14.50 [95% CI, 1.38-152.72]; p=0.022).
  
  
  CONCLUSIONS
  Our study suggests that the incidence of IBS among patients with culture-proven bacterial gastroenteritis within a community is similar to that reported among Western populations. A large, prospective study is encouraged to confirm our results and to evaluate the influence of the microbial species on the epidemiology of IBS in Asian populations.
authors: Epidemic Intelligence Service, Division of Public Health Policy, Gyeonggi Provincial Office, South Korea.
authors: Seong-Joon
authors: SJ
authors: Koh
authors: Dong Ho
authors: DH
authors: Lee
authors: Sang Hyub
authors: SH
authors: Lee
authors: Young Soo
authors: YS
authors: Park
authors: Jin Hyeok
authors: JH
authors: Hwang
authors: Jin Wook
authors: JW
authors: Kim
authors: Sook Hyang
authors: SH
authors: Jeong
authors: Nayoung
authors: N
authors: Kim
authors: Jong Pil
authors: JP
authors: Im
authors: Joo Sung
authors: JS
authors: Kim
authors: Hyun Chae
authors: HC
authors: Jung
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D003967:Diarrhea / Q000150:complications; D004403:Dysentery / Q000150:complications; D005260:Female; D005500:Follow-Up Studies; D005759:Gastroenteritis / Q000150:complications* / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D015994:Incidence; D043183:Irritable Bowel Syndrome / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011446:Prospective Studies; D012307:Risk Factors; D012475:Salmonella / Q000302:isolation & purification; D012760:Shigella / Q000302:isolation & purification; D055815:Young Adult