title: Chloroquine-resistant malaria in travelers returning from Haiti after 2010 earthquake.
abstract: We investigated chloroquine sensitivity to Plasmodium falciparum in travelers returning to France and Canada from Haiti during a 23-year period. Two of 19 isolates obtained after the 2010 earthquake showed mixed pfcrt 76K+T genotype and high 50% inhibitory concentration. Physicians treating malaria acquired in Haiti should be aware of possible chloroquine resistance.
authors: Myriam
authors: M
authors: Gharbi
authors: Dylan R
authors: DR
authors: Pillai
authors: Rachel
authors: R
authors: Lau
authors: Véronique
authors: V
authors: Hubert
authors: Krishna
authors: K
authors: Khairnar
authors: Alexandre
authors: A
authors: Existe
authors: Eric
authors: E
authors: Kendjo
authors: Sabina
authors: S
authors: Dahlström
authors: Philippe J
authors: PJ
authors: Guérin
authors: Jacques
authors: J
authors: Le Bras
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000962:Antimalarials / Q000494:pharmacology / Q000627:therapeutic use; D002170:Canada / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D002738:Chloroquine / Q000494:pharmacology* / Q000627:therapeutic use; D004190:Disasters; D004351:Drug Resistance / Q000235:genetics*; D055866:Earthquakes; D005260:Female; D005602:France / Q000453:epidemiology; D005838:Genotype; D006205:Haiti; D006801:Humans; D007223:Infant; D016778:Malaria, Falciparum / Q000188:drug therapy / Q000469:parasitology; D008297:Male; D026901:Membrane Transport Proteins / Q000235:genetics; D008875:Middle Aged; D021261:Parasitic Sensitivity Tests; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D015800:Protozoan Proteins / Q000235:genetics; D014195:Travel; D055815:Young Adult
chemical_list: D000962:Antimalarials; D026901:Membrane Transport Proteins; C416369:PfCRT protein, Plasmodium falciparum; D015800:Protozoan Proteins; D002738:Chloroquine