title: A facile two-step etching method to fabricate porous hollow silica particles.
abstract: We report here the fabrication of hollow silica particles with mesopores larger than 10nm on their wall via a facile two-step etching method. Different from the conventional template method, the new method uses the silica particles as starting materials, which were synthesized using the well-known Stöber method. In the hollow silica preparation, first, we gently etch the silica particles with a NaOH solution without using template molecules to make them porous. Then, we coat the porous silica particles with poly-dimethyldiallylammonium chloride (PDDA) and treat the PDDA-coated porous silica with an ammonia solution to form the hollow silica nanospheres. In this study, we found that the NaOH dosage and ammonia concentration have significant impact on the morphology of the final products. Adsorption was also studied and results show that the hollow nanospheres can effectively uptake protein-based biomolecules (hemoglobin).
authors: State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, PR China.
authors: Qingnan
authors: Q
authors: Meng
authors: Siyuan
authors: S
authors: Xiang
authors: Kai
authors: K
authors: Zhang
authors: Mingyang
authors: M
authors: Wang
authors: Xinyuan
authors: X
authors: Bu
authors: Pengfei
authors: P
authors: Xue
authors: Liqun
authors: L
authors: Liu
authors: Hongchen
authors: H
authors: Sun
authors: Bai
authors: B
authors: Yang
mesh_terms: D000327:Adsorption; D000641:Ammonia / Q000737:chemistry; D000818:Animals; D002417:Cattle; D006454:Hemoglobins / Q000737:chemistry*; D055767:Immobilized Proteins / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D054118:Nanospheres / Q000737:chemistry* / Q000648:ultrastructure; D011095:Polyethylenes / Q000737:chemistry; D016062:Porosity; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry*; D012972:Sodium Hydroxide / Q000737:chemistry
chemical_list: D006454:Hemoglobins; D055767:Immobilized Proteins; D011095:Polyethylenes; D000644:Quaternary Ammonium Compounds; C041004:poly-N,N-dimethyl-N,N-diallylammonium chloride; D012972:Sodium Hydroxide; D012822:Silicon Dioxide; D000641:Ammonia