title: Cutaneous leishmaniasis in northeastern Brazil: a critical appraisal of studies conducted in State of Pernambuco.
abstract: American cutaneous leishmaniasis (ACL) is a complex disease with clinical and epidemiological features that may vary from region to region. In fact, at least seven different Leishmania species, including Leishmania (Viannia) braziliensis, Leishmania (Viannia) guyanensis, Leishmania (Viannia) lainsoni, Leishmania (Viannia) naiffi, Leishmania (Viannia) shawi, Leishmania (Viannia) lindenbergi, and Leishmania (Leishmania) amazonensis, have been implicated in the etiology of ACL in Brazil, and numerous phlebotomine sandfly species of the genus Lutzomyia have been regarded as putative or proven vectors. Because ACL is a focal disease, understanding the disease dynamics at the local level is essential for the implementation of more effective control measures. The present paper is a narrative review about the ACL epidemiology in Pernambuco, northeastern Brazil. Furthermore, the need for more effective diagnosis, treatment, control and prevention strategies for the affected populations is highlighted. This paper will provide researchers with a critical appraisal of ACL in Pernambuco. Hopefully, it will also be helpful for public health authorities to improve current control strategies against ACL at the state and country levels.
authors: Centro de Pesquisas Aggeu Magalhães, Fundação Oswaldo Cruz, Recife, PE, Brasil. britomef@cpqam.fiocruz.br
authors: Maria Edileuza Felinto
authors: ME
authors: de Brito
authors: Maria Sandra
authors: MS
authors: Andrade
authors: Filipe
authors: F
authors: Dantas-Torres
authors: Eduardo Henrique Gomes
authors: EH
authors: Rodrigues
authors: Milena de Paiva
authors: Mde P
authors: Cavalcanti
authors: Alzira Maria Paiva
authors: AM
authors: de Almeida
authors: Sinval Pinto
authors: SP
authors: Brandão-Filho
mesh_terms: D000818:Animals; D044822:Biodiversity; D001938:Brazil / Q000453:epidemiology; D004197:Disease Reservoirs / Q000145:classification*; D006801:Humans; D007303:Insect Vectors / Q000145:classification*; D007891:Leishmania / Q000145:classification*; D016773:Leishmaniasis, Cutaneous / Q000453:epidemiology* / Q000635:transmission / Q000662:veterinary; D011576:Psychodidae / Q000145:classification*