title: The degradation of alkylphenols by Sphingomonas sp. strain TTNP3 - a review on seven years of research.
abstract: Over the past seven years, we have been working with Sphingomonas sp. strain TTNP3, a bacterium capable of growing on numerous alkylphenolic compounds as a source of carbon and energy. We succeeded in elucidating an unusual pathway involving an attack at the quaternary alpha-carbon atom of the substrate, a position previously thought to be highly resistant to biodegradation. Combining analytical and bioanalytical methods, a good understanding of the reaction mechanisms, the enzymes catalysing them and the organization of the genes encoding them could be gained. First studies on the use of Sphingomonas sp. strain TTNP3 in wastewater treatment have been performed revealing promising results.
authors: Institute for Ecopreneurship, School of Life Sciences, University of Applied Sciences and Arts, Northwestern Switzerland, Muttenz, Switzerland.
authors: B A
authors: BA
authors: Kolvenbach
authors: P F-X
authors: PF
authors: Corvini
mesh_terms: D001673:Biodegradation, Environmental; D019149:Bioreactors / Q000382:microbiology; D053858:Metabolic Networks and Pathways; D010636:Phenols / Q000737:chemistry / Q000378:metabolism*; D012106:Research; D020578:Sphingomonas / Q000235:genetics / Q000378:metabolism*
chemical_list: D010636:Phenols