title: Large monophasic synovial sarcoma of the mediastinum in a 15-year old boy.
abstract: We present the interesting case of a 15-year old boy with a monophasic synovial sarcoma (MSS) of the mediastinum, which was infiltrating the right heart chambers and the inferior vena cava (IVC). A radical excision was performed, with extensive reconstruction of the heart, under deep hypothermic circulatory arrest. Radical surgical excision is considered to be the treatment of choice for these lesions, as chemotherapy and radiotherapy have little effect. Unfortunately, the patient and his parents refused any further consultation with an oncologist and, although there was no recurrence at 12 months following the procedure, at 24 months we were informed of his death due to the tumour appearing on the left cardiac chambers with subsequent multi-organ failure.
authors: Department of Paediatric and Congenital Cardiac Surgery, Onassis Heart Centre, Kallithea, Athens, Greece. dr_spylog@yahoo.co.uk
authors: Spiros
authors: S
authors: Loggos
authors: Konstandinos
authors: K
authors: Kondrafouris
authors: George
authors: G
authors: Oikonomopoulos
authors: Fotios
authors: F
authors: Mitropoulos
mesh_terms: D000293:Adolescent; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass; D050792:Circulatory Arrest, Deep Hypothermia Induced; D018450:Disease Progression; D017809:Fatal Outcome; D006325:Heart Atria / Q000473:pathology / Q000601:surgery; D006352:Heart Ventricles / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D009102:Multiple Organ Failure / Q000209:etiology; D009361:Neoplasm Invasiveness; D019651:Plastic Surgery Procedures; D013584:Sarcoma, Synovial / Q000150:complications / Q000473:pathology* / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome; D047368:Tumor Burden; D014682:Vena Cava, Inferior / Q000473:pathology / Q000601:surgery