title: [COX-2 as an early diagnostic marker of virus-associated human malignant neoplasms].
abstract: The review analyzes recent data and current ideas on the enzyme cyclooxygenase 2 (COX-2) as a possible biomarker of virus-associated human malignant neoplasm. Possible mechanisms of COX-2 activation in the cells infected with oncogenic human viruses, such as hepatitis B virus, Epstein-Barr virus, and human papillomavirus are considered in detail.
authors: S V
authors: SV
authors: Diduk
authors: K V
authors: KV
authors: Smirnova
authors: V É
authors: VÉ
authors: Gurtsevich
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism*; D051546:Cyclooxygenase 2 / Q000378:metabolism*; D042241:Early Diagnosis; D006515:Hepatitis B virus / Q000378:metabolism; D004854:Herpesvirus 4, Human / Q000378:metabolism; D006801:Humans; D027383:Papillomaviridae / Q000378:metabolism; D014412:Tumor Virus Infections / Q000175:diagnosis* / Q000201:enzymology / Q000821:virology
chemical_list: D014408:Biomarkers, Tumor; D051546:Cyclooxygenase 2