title: Surgical management of bilateral parotid lipomatosis in a patient with HIV.
abstract: BACKGROUND
  The long-term use of highly active antiretroviral therapy (HAART) in patients with human immunodeficiency virus (HIV) has led to sequelae including lipodystrophy syndrome (LDS). We present the first published case of surgical management of bilateral parotid lipomatosis in a patient with HIV on long-term HAART.
  
  
  METHODS
  We undertook review of the case notes from the time of diagnosis with HIV and literature review of this topic.
  
  
  RESULTS
  A 45-year-old man with HIV on HAART presented with a 4-year history of increasing bilateral facial swelling. He was asymptomatic apart from the stigmatizing cosmetic deformity. MRI revealed the parotid glands had been replaced by fat. He elected for surgery and parotid lipomatosis was diagnosed on histopathological examination.
  
  
  CONCLUSIONS
  Lipohypertrophy in LDS is rare in the literature and this presentation of bilateral parotid lipomatosis secondary to HAART is only the third reported case, and the first to undergo surgical resection.
authors: Department of Otolaryngology, Imperial College Hospitals NHS Trust, London, United Kingdom. cunningham.aileen@gmail.com
authors: Aileen L
authors: AL
authors: Cunningham
authors: Ali S
authors: AS
authors: Taghi
authors: Gurmit Kaur Jagjit
authors: GK
authors: Singh
authors: Ann
authors: A
authors: Sandison
authors: Charlotte E
authors: CE
authors: Cohen
authors: William E
authors: WE
authors: Grant
mesh_terms: D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D008068:Lipomatosis / Q000139:chemically induced / Q000175:diagnosis / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010305:Parotid Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000601:surgery*