title: Ingestion of a single serving of saury alters postprandial levels of plasma n-3 polyunsaturated fatty acids and long-chain monounsaturated fatty acids in healthy human adults.
abstract: BACKGROUND
  Saury oil contains considerable amounts of n-3 polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA) with long aliphatic tails (>18C atoms). Ingestion of saury oil reduces the risk of developing metabolic syndrome concomitant with increases in n-3 PUFA and long-chain MUFA in plasma and organs of mice. We therefore evaluated changes in postprandial plasma fatty acid levels and plasma parameters in healthy human subjects after ingestion of a single meal of saury.
  
  
  RESULTS
  Five healthy human adults ingested 150 g of grilled saury. Blood was collected before the meal and at 2, 6, and 24 hr after the meal, and plasma was prepared. Plasma levels of eicosapentaenoic acid, docosahexaenoic acid, and long-chain MUFA (C20:1 and C22:1 isomers combined) increased significantly throughout the postprandial period compared with the pre-meal baseline. Postprandial plasma insulin concentration increased notably, and plasma levels of glucose and free fatty acids decreased significantly and subsequently returned to the pre-meal levels.
  
  
  CONCLUSIONS
  Our study suggests that a single saury meal may alter the postprandial plasma levels of n-3 PUFA and long-chain MUFA in healthy human subjects.
authors: Central Research Laboratory, Tokyo Innovation Center, Nippon Suisan Kaisha, Ltd., Tokyo, Japan. yangzh@nissui.co.jp
authors: Zhi-Hong
authors: ZH
authors: Yang
authors: Hiroko
authors: H
authors: Miyahara
authors: Jiro
authors: J
authors: Takeo
authors: Masashi
authors: M
authors: Katayama
mesh_terms: D000328:Adult; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D004281:Docosahexaenoic Acids / Q000097:blood; D015118:Eicosapentaenoic Acid / Q000097:blood; D005229:Fatty Acids, Monounsaturated / Q000097:blood*; D015525:Fatty Acids, Omega-3 / Q000097:blood*; D005260:Female; D005395:Fish Oils / Q000008:administration & dosage* / Q000737:chemistry; D005399:Fishes / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000517:prevention & control; D051379:Mice; D019518:Postprandial Period
chemical_list: D001786:Blood Glucose; D005229:Fatty Acids, Monounsaturated; D015525:Fatty Acids, Omega-3; D005395:Fish Oils; D007328:Insulin; D004281:Docosahexaenoic Acids; D015118:Eicosapentaenoic Acid