title: [Detection for retinal pigment epithelial lesions in fellow eye of age-related macular degeneration by retro-mode].
abstract: OBJECTIVE
  Using the Retro-mode (RM), to detect drusen and other minute lesions of the retinal pigment epithelium (RPE) invisible in current imaging methods in the fellow eye of Japanese patients with exudative age-related macular degeneration(AMD).
  
  
  METHODS
  A retrospective cross-sectional study.
  
  
  METHODS
  The fellow eyes of nineteen Japanese patients with unilateral exudative AMD were examined using RM imaging (F-10 fundus camera, Nidek), in contrast with fluorescein angiography, indocyanine green angiography, and optic coherence tomography (3D OCT-1000, Topcon Co). We were able to identify the type of drusen and minute granular lesions (MGLs) in the RPE.
  
  
  RESULTS
  In all patients, RM imaging gave easier to identify images of all types of drusen than other current imaging methods. Moreover, MGLs of the RPE either adjacent to drusen or without drusen, invisible in other current methods, were detected by RM imaging.
  
  
  CONCLUSIONS
  The RM provides clearer imaging of all kind of drusen, and MGLs of the RPE invisible with current methods. These MGLs are possible precursors of drusen.
authors: Souen Muneyasu Eye Clinic, Sapporo, Japan. takedamnjp@ybb.ne.jp
authors: Muneyasu
authors: M
authors: Takeda
authors: Yui
authors: Y
authors: Sato
authors: Tetsuo
authors: T
authors: Ogino
authors: Hiroko
authors: H
authors: Imaizumi
authors: Utako
authors: U
authors: Okushiba
authors: Takamasa
authors: T
authors: Kinoshita
authors: Hirotomo
authors: H
authors: Miyamoto
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007834:Lasers; D008268:Macular Degeneration / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy / Q000379:methods*; D015594:Optic Disk Drusen / Q000473:pathology; D055213:Retinal Pigment Epithelium / Q000473:pathology*; D012189:Retrospective Studies