title: Phytosterol supplementation does not affect plasma antioxidant capacity in patients with metabolic syndrome.
abstract: Several studies have observed decreased levels of lipophilic antioxidants after supplementation with phytosterols and stanols. The aim of this study was to examine the effect of phytosterol supplementation on plasma total antioxidant capacity in patients with metabolic syndrome. In a parallel arm, randomized placebo-controlled design, 108 patients with metabolic syndrome were assigned to consume yogurt beverage which provided 4 g of phytosterols per day or yogurt beverage without phytosterols. The duration of the study was 2 months and the patients in both groups followed their habitual westernized type diet. Blood samples were drawn at baseline and after 2 months, and the total antioxidant capacity of plasma was measured using the ferric reducing antioxidant power of plasma and oxygen radical absorbance capacity assays. After 2 months of intervention, plasma total antioxidant capacity did not differ between and within the intervention and the control groups. Phytosterol supplementation does not affect plasma antioxidant status.
authors: Unit of Human Nutrition, Department of Food Science and Technology, Agricultural University of Athens, Athens, Greece.
authors: Theodora-Eirini
authors: TE
authors: Sialvera
authors: Antonios E
authors: AE
authors: Koutelidakis
authors: Dimitris J
authors: DJ
authors: Richter
authors: Georgia
authors: G
authors: Yfanti
authors: Maria
authors: M
authors: Kapsokefalou
authors: Renata
authors: R
authors: Micha
authors: Giorgos
authors: G
authors: Goumas
authors: Emmanouil
authors: E
authors: Diamantopoulos
authors: Antonis
authors: A
authors: Zampelas
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000378:metabolism*; D001628:Beverages; D019587:Dietary Supplements / Q000009:adverse effects; D005260:Female; D005290:Ferric Compounds / Q000378:metabolism; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood*; D008875:Middle Aged; D010840:Phytosterols / Q000009:adverse effects / Q000494:pharmacology*; D017382:Reactive Oxygen Species / Q000378:metabolism; D015014:Yogurt
chemical_list: D000975:Antioxidants; D005290:Ferric Compounds; D010840:Phytosterols; D017382:Reactive Oxygen Species