title: Asymmetric synthesis of enaminophosphines via palladacycle-catalyzed addition of Ph2PH to α,β-unsaturated imines.
abstract: A highly reactive, chemo- and enantioselective addition of diphenylphosphine to α,β-unsaturated imines catalyzed by a palladacycle has been developed, thus providing the access to a series of chiral tertiary enaminophosphines in high yields. A putative catalytic cycle has also been proposed.
authors: Division of Chemistry & Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, Singapore 637371.
authors: Yinhua
authors: Y
authors: Huang
authors: Renta Jonathan
authors: RJ
authors: Chew
authors: Sumod A
authors: SA
authors: Pullarkat
authors: Yongxin
authors: Y
authors: Li
authors: Pak-Hing
authors: PH
authors: Leung
mesh_terms: D002384:Catalysis; D007097:Imines / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D010720:Phosphines / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007097:Imines; D010720:Phosphines; D010165:Palladium