title: Medium-sized and strained heterocycles from non-catalysed and gold-catalysed conversions of β-carbolines.
abstract: 2-Allyl-1-vinyl-β-carbolines and dihydropyrrolo-β-carbolines react with activated internal alkynes through novel rearrangement reactions leading to complex polycyclic structures. Favored reaction pathways depend on reaction conditions and on the presence of gold catalysts. In particular, upon reaction with 2 equiv. of the alkyne, new hexacyclic structures 10 are formed with total stereocontrol.
authors: Universidad San Pablo-CEU, Departamento de Química, Facultad de Farmacia, Madrid, Spain.
authors: Sandra
authors: S
authors: Medina
authors: Alvaro
authors: A
authors: González-Gómez
authors: Gema
authors: G
authors: Domínguez
authors: Javier
authors: J
authors: Pérez-Castells
mesh_terms: D000480:Alkynes / Q000737:chemistry; D000498:Allyl Compounds / Q000737:chemistry; D002243:Carbolines / Q000737:chemistry*; D002384:Catalysis; D006046:Gold / Q000737:chemistry; D011758:Pyrroles / Q000737:chemistry
chemical_list: D000480:Alkynes; D000498:Allyl Compounds; D002243:Carbolines; D011758:Pyrroles; D006046:Gold