title: Circadian biology: a 2.5 billion year old clock.
abstract: A recent study suggests that circadian clocks may have evolved at the time of the Great Oxidation Event 2.5 billion years ago in order to drive detoxification of reactive oxygen species.
authors: Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK. andrew.loudon@manchester.ac.uk
authors: Andrew S I
authors: AS
authors: Loudon
mesh_terms: D005075:Biological Evolution; D057906:Circadian Clocks; D002940:Circadian Rhythm; D056890:Eukaryota / Q000235:genetics / Q000378:metabolism*; D019143:Evolution, Molecular; D019419:Evolution, Planetary; D006217:Halobacterium / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D054464:Peroxiredoxins / Q000235:genetics / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism; D046940:Synechococcus / Q000235:genetics / Q000378:metabolism*
chemical_list: D017382:Reactive Oxygen Species; D054464:Peroxiredoxins