title: Effect of extended wear disposable contact lenses on tear LTC4 in giant papillary conjunctivitis.
abstract: Disposable contact lenses have been proposed as an alternative treatment of giant papillary conjunctivitis (GPC), a common contact lens complication associated with increased tear inflammatory mediators, especially LTC(4).   In this study, tear LTC(4) was determined by ELISA in tears from eight patients, fitted with disposable contact lenses for the treatment of manifest GPC.   An initial decrease in tear LTC(4) in the first ten days of disposable contact lens wear was later followed by increased LTC(4) in six of eight patients (75%) at the end of the first month of disposable contact lens wear.   The results of this study indicate that extended wear disposable contact lenses might have a limited place in GPC treatment, since they do not prevent pathogenic inflammatory mediator response in the long term.
authors: Department of Ophthalmology, Hacettepe School of Medicine, Ankara, Turkey.
authors: M
authors: M
authors: Irkeç
authors: M
authors: M
authors: Orhan