title: [Specificity of exposure of the indigenous dwellers of coastal and inland Chukotka to dichlorodiphenyltrichloroethane].
abstract: In the indigenous dwellers of coastal Chukotka, blood DDT levels are 1.5-2 times higher than those of continental areas, which is due to the higher global DDT pollution of a sea food chain. The blood levels of 4,4-DDE in the reproductive-age women of coastal Chukotka are comparable to those in other Russian Arctic regions, slightly lower than in Greenland, but essentially higher than in Canada, Alaska and Scandinavian countries. Blood DDE/DDT ratio in the coastal indigenous dwellers is almost twice higher than that in the inland inhabitants, which is indicative of the "older" exposure of coastal people to DDT. There was an about equal (70-75%) decrease in 4,4-DDE and 4,4-DDT levels with a practically invariable ratio (12-15) and a nearly equal elimination half-life period (about 3.5 years) in the mothers of coastal Chukotka 5 years after the first examination. The elevated 4,4-DDE/4,4-DDT ratios in the tissues of sea mammals generally correspond to higher isomer ratios in the blood of coastal natives and relatively low 4,4-DDE/4,4-DDT ratios in the venison, fowl, and fish predetermine lower ratios in the blood of inland inhabitants. The extremely low of DDE/DDT ratio (0.4) in the washouts and scrapes from the kitchen walls of dwellings are conclusively associated with the recent application of DDT as a household insecticide.
authors: A A
authors: AA
authors: Dudarev
authors: V S
authors: VS
authors: Chupachin
authors: Z S
authors: ZS
authors: Ivanova
authors: G B
authors: GB
authors: Lebedev
mesh_terms: D000328:Adult; D001110:Arctic Regions; D015331:Cohort Studies; D003634:DDT / Q000097:blood*; D003633:Dichlorodiphenyl Dichloroethylene / Q000097:blood*; D004781:Environmental Exposure / Q000009:adverse effects / Q000032:analysis*; D004785:Environmental Pollutants / Q000097:blood*; D005260:Female; D020387:Food Chain; D005506:Food Contamination / Q000032:analysis; D006801:Humans; D008297:Male; D012426:Russia
chemical_list: D004785:Environmental Pollutants; D003633:Dichlorodiphenyl Dichloroethylene; D003634:DDT