title: Catalytic asymmetric [4+2] annulation initiated by an aza-Rauhut-Currier reaction: facile entry to highly functionalized tetrahydropyridines.
abstract: Under control: The first example of chiral amino phosphine catalysts for the title reaction between vinyl ketones and N-sulfonyl-1-aza-1,3-dienes has been developed. Under ambient conditions, this protocol provides straightforward access to densely functionalized, enantioenriched tetrahydropyridines with high levels of sterecontrol in good to excellent yields.
authors: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University, 16 Xue-Lin Street, Hangzhou 310036, Zhejiang, China.
authors: Zugui
authors: Z
authors: Shi
authors: Peiyuan
authors: P
authors: Yu
authors: Teck-Peng
authors: TP
authors: Loh
authors: Guofu
authors: G
authors: Zhong
mesh_terms: D002384:Catalysis; D003500:Cyclization; D015394:Molecular Structure; D010720:Phosphines / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D010720:Phosphines; D011725:Pyridines