title: Primary candidiasis and squamous cell carcinoma of the larynx: report of a case.
abstract: Primary candidiasis is rare and often confused with a pre-cancerous lesion, squamous cell carcinoma, or verrucous carcinoma. We report an extremely rare case of squamous cell carcinoma of the vocal cord following primary candidiasis. A 62-year-old man presented to our department reporting a 1-month history of hoarseness. He underwent laryngeal microscopic surgery for a presumptive diagnosis of glottic carcinoma. Histopathologic examination revealed candidiasis and scattered moderate dysplasia. He was treated with itraconazole for 4 weeks, and followed up without any recurrence of candidiasis. However, the 42-month follow-up examination revealed a focal whitish lesion on the right true vocal cord, and a repeat biopsy of this area revealed squamous cell carcinoma without evidence of candidiasis. The patient was treated with radiotherapy and remains well with no signs of tumor recurrence or candidiasis.
authors: Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School, Chonnam National University Hwasun Hospital, 160 Ilsimri, Hwasun, Jeonnam 519-809, South Korea.
authors: Dong Hoon
authors: DH
authors: Lee
authors: Hyong Ho
authors: HH
authors: Cho
mesh_terms: D002177:Candidiasis / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000382:microbiology*; D008297:Male; D008875:Middle Aged