title: Universal fingerprinting chip server.
abstract: The Virtual Hybridization approach predicts the most probable hybridization sites across a target nucleic acid of known sequence, including both perfect and mismatched pairings. Potential hybridization sites, having a user-defined minimum number of bases that are paired with the oligonucleotide probe, are first identified. Then free energy values are evaluated for each potential hybridization site, and if it has a calculated free energy of equal or higher negative value than a user-defined free energy cut-off value, it is considered as a site of high probability of hybridization. The Universal Fingerprinting Chip Applications Server contains the software for visualizing predicted hybridization patterns, which yields a simulated hybridization fingerprint that can be compared with experimentally derived fingerprints or with a virtual fingerprint arising from a different sample.
  
  
  BACKGROUND
  The database is available for free at http://bioinformatica.homelinux.org/UFCVH/
authors: Laboratory of Biotechnology and Genomic Bioinformatics, Department of Biochemistry, National School of Biological Sciences, National Polytechnic Institute, CP 11340, Mexico City, Mexico.
authors: Janet
authors: J
authors: Casique-Almazán
authors: Violeta
authors: V
authors: Larios-Serrato
authors: Gabriela Edith
authors: GE
authors: Olguín-Ruíz
authors: Carlos Javier
authors: CJ
authors: Sánchez-Vallejo
authors: Rogelio
authors: R
authors: Maldonado-Rodríguez
authors: Alfonso
authors: A
authors: Méndez-Tenorio