title: Epidemiological characteristics of Japanese encephalitis in Guizhou Province, China, 1971-2009.
abstract: OBJECTIVE
  The aim of the study was to establish the contemporary epidemiological characteristics of Japanese encephalitis (JE) in Guizhou Province.
  
  
  METHODS
  A retrospective study of National Notifiable Disease Reporting System (NNDRS) data from 1971 through 2009, was conducted to ascertain the geographical, seasonal, and age distributions of JE incidence in Guizhou Province, China.
  
  
  RESULTS
  A total of 68 425 JE cases were reported in Guizhou from 1971-2009. The JE cases occurred sporadically in all 9 prefectures of Guizhou, mostly among residents of rural areas. Seasonal distribution of JE remained consistent over the period from 1971-2009 with the main transmission season starting from June to September and peaking in August. JE occurred mainly in children under the age of 15 years with peak incidence in the 0-6-year age group. Pearson's correlation analysis showed that JE vaccine distribution had a negative correlation with JE incidence rates during 1971-2009 (coefficient of correlation=-0.475, P<0.01).
  
  
  CONCLUSIONS
  Over the period of 1971-2009, the JE incidence rate had declined dramatically in terms of geographical and age distributions due to JE vaccination to children at risk.
authors: West China School of Public Health, Sichuan University, Chengdu 610041, Sichua, China. zhangli@gzcdc.gov.cn
authors: Li
authors: L
authors: Zhang
authors: Rong Sheng
authors: RS
authors: Luan
authors: Feng
authors: F
authors: Jiang
authors: Li Ping
authors: LP
authors: Rui
authors: Min
authors: M
authors: Liu
authors: Yi Xing
authors: YX
authors: Li
authors: Zun Dong
authors: ZD
authors: Yin
authors: Hui Min
authors: HM
authors: Luo
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004672:Encephalitis, Japanese / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D012621:Seasons; D013997:Time Factors; D014765:Viral Vaccines / Q000276:immunology
chemical_list: D014765:Viral Vaccines