title: Expanding indications for resynchronization therapy.
abstract: Cardiac resynchronization therapy (CRT) is one of the major advances in the treatment of patients with chronic heart failure due to impaired left ventricular ejection fraction. Current guidelines recommend with the highest levels of recommendation and evidence CRT in patients with low ejection fraction wide QRS, LBBB, and mild to severe heart failure (New York Heart Association class II to IV). However, other patients might benefit from CRT. This is the case for patients with permanent atrial fibrillation, patients conventional pacemaker indication, patients with mildly impaired left ventricular function (>35 %), or asymptomatic patients (NYHA I). We will discuss in this manuscript each new potential indication for CRT.
authors: CHU Rennes, Service de Cardiologie et Maladies Vasculaires, INSERM 100, CIC-IT, Centre Cardio-Pneumologique, Hôpital Pontchaillou, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 09, France. christophe.leclercq@chu-rennes.fr
authors: Christophe
authors: C
authors: Leclercq
authors: Nathalie
authors: N
authors: Behar
authors: Philippe
authors: P
authors: Mabo
authors: Jean-Claude
authors: JC
authors: Daubert
mesh_terms: D001281:Atrial Fibrillation / Q000628:therapy*; D001919:Bradycardia / Q000628:therapy*; D002304:Cardiac Pacing, Artificial / Q000379:methods; D058406:Cardiac Resynchronization Therapy / Q000379:methods*; D058409:Cardiac Resynchronization Therapy Devices; D017147:Defibrillators, Implantable; D018450:Disease Progression; D004562:Electrocardiography; D006333:Heart Failure / Q000628:therapy*; D006801:Humans; D010138:Pacemaker, Artificial; D013318:Stroke Volume; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000628:therapy*; D020257:Ventricular Remodeling