title: Eco-friendly synthesis and biological evaluation of substituted pyrano[2,3-c]pyrazoles.
abstract: An ecofriendly green approach for synthesis of substituted pyrano[2,3-c]pyrazoles has been developed via a multicomponent one pot approach in aqueous ethanol medium under totally non-catalytic conditions. The synthesized compounds were evaluated for their antibacterial, anti-inflammatory and cytotoxic activities.
authors: Crop Protection Chemicals Division, Indian Institute of Chemical Technology, Tarnaka, Hyderabad 500607, India.
authors: Santhosh Reddy
authors: SR
authors: Mandha
authors: Sravanthi
authors: S
authors: Siliveri
authors: Manjula
authors: M
authors: Alla
authors: Vittal Rao
authors: VR
authors: Bommena
authors: Madhava Reddy
authors: MR
authors: Bommineni
authors: Sridhar
authors: S
authors: Balasubramanian
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis* / Q000627:therapeutic use / Q000633:toxicity; D049109:Cell Proliferation / Q000187:drug effects; D018360:Crystallography, X-Ray; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006801:Humans; D061986:MCF-7 Cells; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D011720:Pyrazoles / Q000737:chemistry* / Q000627:therapeutic use / Q000633:toxicity; D051381:Rats
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D011720:Pyrazoles