title: A case of cutaneous large B-cell lymphoma of the legs appearing as chronic venous ulceration.
abstract: We report here a case of a woman with a cutaneous large B-cell lymphoma of the legs. She had a plaque lesion, superficially ulcerated and necrotized with tumorous borders situated on the posterior side of the right leg and two red or bluish-red nodular lesions. A skin biopsy from both nodular and plaque lesion showed a diffuse infiltrate of atypical large B cells CD20(+) and CD79a(+), spanning epidermis, dermis and subcutaneous tissue. A therapeutic approach containing anti-CD20 monoclonal antibody (rituximab) was suggested.
authors: Dermatology Unit, S.Andrea Hospital, Faculty of Medicine and Psychology University of Rome La Sapienza, Italy.
authors: Marta
authors: M
authors: Carlesimo
authors: Diego
authors: D
authors: Orsini
authors: Alessandra
authors: A
authors: Narcisi
authors: Claudia
authors: C
authors: Abruzzese
authors: Giorgia
authors: G
authors: Cortesi
authors: Gabriella
authors: G
authors: De Marco
authors: Alfredo
authors: A
authors: Rossi