title: Effect of single and repeated injections of selective D2-antagonist clebopride on maternal behavior of albino rats.
abstract: This study examined the effect of clebopride at low concentration that did not modify the motor activity on the parental care in female albino rats. Single injection of the drug attenuated the parental care reactions on postinjection minute 20, but not one day thereafter. The daily injection of the drug during the post partum period (1-6 days) resulted in significantly more pronounced and stable effects. The data obtained substantiated the views on the major contribution of D(2)-receptors in the development of behavioral manifestations of puerperal depression.
authors: Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University, Russia. ksetan@mail.ru
authors: K K
authors: KK
authors: Tanaeva
authors: Yu V
authors: YV
authors: Dobryakova
authors: V A
authors: VA
authors: Dubynin
authors: A A
authors: AA
authors: Kamensky
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001549:Benzamides / Q000008:administration & dosage / Q000494:pharmacology*; D065127:Dopamine D2 Receptor Antagonists; D005260:Female; D008425:Maternal Behavior / Q000187:drug effects*; D009043:Motor Activity / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D001549:Benzamides; D065127:Dopamine D2 Receptor Antagonists; C014417:clebopride