title: [Effect of intraoperative infusion-transfusion therapy on mortality of patients with massive blood loss].
abstract: The aim of the research is to determine the influence of infusion-transfusion therapy of the volume and structure on intraoperation and hospital lethality in patients with injuries and diseases, complicated in blood loss, exceeding circulating blood volume (CBV). It was conducted a retrospective analysis of the anaesthesia flow, infusion-transfusion therapy and treatment results in 112 patients with injuries and diseases complicated in intra-abdominal bleeding, volume of more than 4 liters. It was found that the risk of death increases in low-volume infusion therapy (less than 1.5 volume of blood), use of the maximum permitted doses of colloids, high speed of infusion therapy. Adverse factors of intraoperative transfusion: the lack of intraoperative compensation erythrocytes(less than 50% of the lost), ones transfuse more than 2 standard doses of the donor's erythrocytes and large volumes of fresh frozen plasma (FFP).
authors: V V
authors: VV
authors: Valetova
authors: A S
authors: AS
authors: Ermolov
authors: V Kh
authors: VKh
authors: Timerbaev
authors: A V
authors: AV
authors: Dragunov
mesh_terms: D001803:Blood Transfusion / Q000379:methods / Q000401:mortality; D005260:Female; D006470:Hemorrhage / Q000209:etiology / Q000401:mortality / Q000601:surgery; D006801:Humans; D007430:Intraoperative Care / Q000379:methods / Q000401:mortality; D008297:Male; D008875:Middle Aged; D057725:Operative Blood Salvage; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016019:Survival Analysis; D013997:Time Factors