title: GeneTalk: an expert exchange platform for assessing rare sequence variants in personal genomes.
abstract: CONCLUSIONS
  Next-generation sequencing has become a powerful tool in personalized medicine. Exomes or even whole genomes of patients suffering from rare diseases are screened for sequence variants. After filtering out common polymorphisms, the assessment and interpretation of detected personal variants in the clinical context is an often time-consuming effort. We have developed GeneTalk, a web-based platform that serves as an expert exchange network for the assessment of personal and potentially disease-relevant sequence variants. GeneTalk assists a clinical geneticist who is searching for information about specific sequence variants and connects this user to other users with expertise for the same sequence variant.
  
  
  BACKGROUND
  GeneTalk is available at www.gene-talk.de. Users can login without registering in a demo account.
  
  
  BACKGROUND
  peter.krawitz@gene-talk.de.
authors: GeneTalk, Finckensteinallee 84, 12205 Berlin, Germany.
authors: Tom
authors: T
authors: Kamphans
authors: Peter M
authors: PM
authors: Krawitz
mesh_terms: D019295:Computational Biology / Q000379:methods*; D059472:Exome; D015894:Genome, Human; D006801:Humans; D033181:Information Dissemination / Q000379:methods*; D020407:Internet; D058436:Knowledge Management; D058977:Molecular Sequence Annotation; D011110:Polymorphism, Genetic; D057285:Precision Medicine; D017422:Sequence Analysis, DNA / Q000379:methods*; D012984:Software; D014584:User-Computer Interface