title: Antidiarrhoeal efficacy of Mangifera indica seed kernel on Swiss albino mice.
abstract: OBJECTIVE
  To examine the antidiarrhoeal activity of alcoholic and aqueous seed kernel extract of Mangifera indica (M. indica) on castor oil-induced diarrhoeal activity in Swiss albino mice.
  
  
  METHODS
  Mango seed kernels were processed and extracted using alcohol and water. Antidiarrhoeal activity of the extracts were assessed using intestinal motility and faecal score methods.
  
  
  RESULTS
  Aqueous and alcoholic extracts of M. indica significantly reduced intestinal motility and faecal score in Swiss albino mice.
  
  
  CONCLUSIONS
  The present study shows the traditional claim on the use of M. indica seed kernel for treating diarrhoea in Southern parts of India.
authors: Department of Microbiology, M. R. Govt Arts College, Mannargudi-614 001, Thiruvarur District, Tamilnadu, India.
authors: S
authors: S
authors: Rajan
authors: H
authors: H
authors: Suganya
authors: T
authors: T
authors: Thirunalasundari
authors: S
authors: S
authors: Jeeva
mesh_terms: D000818:Animals; D000930:Antidiarrheals / Q000494:pharmacology / Q000627:therapeutic use*; D002368:Castor Oil; D003967:Diarrhea / Q000139:chemically induced / Q000188:drug therapy*; D004195:Disease Models, Animal; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D008297:Male; D031022:Mangifera; D008519:Medicine, Traditional; D051379:Mice; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D012639:Seeds; D016896:Treatment Outcome
chemical_list: D000930:Antidiarrheals; D010936:Plant Extracts; D002368:Castor Oil