title: Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility.
abstract: OBJECTIVE
  To investigate the relationship between hyaluronan binding (HB) assay and pregnancy rates in intrauterine insemination (IUI) cycles.
  
  
  METHODS
  This prospective cohort study was done in Hacettepe University, a tertiary care center for reproductive medicine. Seventy-one consecutive couples who suffered from unexplained infertility and underwent controlled ovarian hyperstimulation (COH) and IUI were enrolled into the study.
  
  
  RESULTS
  From the 71 IUI patients, the clinical pregnancy rate was 14.1% (10 of 71). HB ratio from the overall patient number was 48.6±25.9. The mean HB ratio in pregnant and non-pregnant groups was comparable (50.2±25.2 vs. 48.3±26.2, respectively, p>0.05).
  
  
  CONCLUSIONS
  Hyaluronan binding assay does not predict pregnancy rates in IUI cycles in couples with unexplained infertility.
authors: Anatolia IVF Center, Ankara, Turkey.
authors: Fazilet Kubra
authors: FK
authors: Boynukalin
authors: Ibrahim
authors: I
authors: Esinler
authors: Suleyman
authors: S
authors: Guven
authors: Serdar
authors: S
authors: Gunalp
mesh_terms: D000328:Adult; D001681:Biological Assay / Q000379:methods*; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000378:metabolism*; D007246:Infertility / Q000628:therapy*; D007315:Insemination, Artificial; D008297:Male; D010062:Ovulation Induction; D011237:Predictive Value of Tests; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies; D055101:Semen Analysis; D013094:Spermatozoa / Q000378:metabolism*; D055815:Young Adult
chemical_list: D006820:Hyaluronic Acid