title: Ultrasound promoted Barbier reactions and Csp3-Csp2 Stille coupling for the synthesis of diarylmethanes and substituted benzophenones.
abstract: Here we present the preparation of a variety of diarylmethanes obtained via ultrasound Stille coupling under palladium catalysis between some substituted aryl compounds and benzyltributyltin compounds generated through sonicated Barbier reaction in a very short time reaction and excellent yield. The study reported below compares different methods to optimize the synthesis of usually unstable benzyltin derivatives and is another contribution to the investigation of Csp(3)-Csp(2) coupling process involving benzyl-aryl reagents. Substituted carboxylated benzophenones were easily prepared in a very good yield by oxidation of some diarylmethanes.
authors: Departamento de Química, Instituto de Química del Sur, INQUISUR, Universidad Nacional del Sur, Avenida Alem 1253, 8000 Bahía Blanca, Argentina.
authors: Romina A
authors: RA
authors: Ocampo
authors: Liliana C
authors: LC
authors: Koll
authors: Sandra D
authors: SD
authors: Mandolesi
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry*; D001577:Benzophenones / Q000138:chemical synthesis* / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D008697:Methane / Q000138:chemical synthesis* / Q000737:chemistry*; D014465:Ultrasonics
chemical_list: D000900:Anti-Bacterial Agents; D001577:Benzophenones; D008697:Methane