title: Comparative cost analysis of three different anesthesia methods in gynecological laparoscopic surgery.
abstract: In the current study, we assessed and evaluated the costs and benefits of three popular methods of general anesthesia practiced in our department for gynecological laparoscopic surgery in recent years. Sixty adult female patients who underwent elective gynecological laparoscopic surgery under general anesthesia were randomly divided into three groups: group V, group I and group C. In group V, anesthesia was induced intravenously with midazolam, remifentanil, propofol and vecuronium, and maintained with continuous infusion of propofol and remifentanil. In group I, anesthesia was intravenously induced with midazolam, fentanyl, propofol and vecuronium, and maintained with inhaled isoflurane and intravenous bonus of fentanyl. In group C, anesthesia was induced as in group I, but maintained with isoflurane inhalation combined with propofolremifentanil infusion. All patients received vecuronium for muscle relaxation. Perioperative incidences of complications and total anesthesia costs for patients in all groups were recorded. In addition, postoperative satisfaction of the patients was also noted, and similar outcomes of the satisfaction were reported in all 60 patients. Although there was no statistical significance among groups, the incidence of postoperative nausea and vomiting were higher in group C, and the rates of shivering and the needs for analgesics were higher in group V. Anesthesia costs in group I were the lowest. Therefore, it is concluded that the costs of anesthesia induced with midazolam, fentanyl, propofol, vecuronium, and maintained with isoflurane, fentanyl and vecuronium are cheapest, and there is no significant difference in patients' satisfaction and safety among the three above-mentioned methods of anesthesia in our department.
authors: Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors: Xiaohui
authors: X
authors: Chi
authors: Yeling
authors: Y
authors: Chen
authors: Mingfeng
authors: M
authors: Liao
authors: Fei
authors: F
authors: Cao
authors: Yuke
authors: Y
authors: Tian
authors: Xueren
authors: X
authors: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D000768:Anesthesia, General / Q000191:economics* / Q000379:methods; D000769:Anesthesia, Inhalation / Q000191:economics; D000771:Anesthesia, Intravenous / Q000191:economics; D000777:Anesthetics / Q000008:administration & dosage* / Q000191:economics; D018685:Anesthetics, Inhalation / Q000191:economics; D018686:Anesthetics, Intravenous / Q000191:economics; D003365:Costs and Cost Analysis; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D010535:Laparoscopy; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000008:administration & dosage / Q000191:economics; D010043:Outcome and Process Assessment, Health Care; D017060:Patient Satisfaction; D011183:Postoperative Complications; D011446:Prospective Studies; D016037:Single-Blind Method
chemical_list: D000777:Anesthetics; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D009125:Muscle Relaxants, Central