title: Post-dengue fever severe aplastic anemia: a rare association.
abstract: Dengue fever has rarely been reported as an etiology for aplastic anemia. An 8-year-old girl was admitted with fever, myalgia and petechiae. Dengue virus IgM antibodies were positive. She recovered completely, but her thrombocytopenia persisted. Six weeks later she became pancytopenic. A bone marrow aspirate and biopsy showed severe aplastic anemia. She was treated with antithymocytic immunoglobulin, methylprednisolone and cyclosporine. She became transfusion independent 6 months later. Dengue-virus induced aplastic anemia is a rare entity, but it must be identified early for better outcome. Immunosuppressive therapy can induce remission.
authors: Pediatric Hematology Oncology and Bone Marrow Transplantation Unit, Department of Pediatrics, Institute of Child Health, Sir Ganga Ram Hospital, Delhi, India.
authors: Mohammed
authors: M
authors: Ramzan
authors: Satya
authors: S
authors: PrakashYadav
authors: Anupam
authors: A
authors: Sachdeva
mesh_terms: D000741:Anemia, Aplastic / Q000628:therapy / Q000821:virology*; D002648:Child; D003715:Dengue / Q000097:blood* / Q000188:drug therapy; D005260:Female; D006801:Humans