title: Gastroesophageal Reflux Disease in Iran: SEPAHAN Systematic Review No. 2.
abstract: BACKGROUND
  Gastroesophageal reflux disease (GERD) is one of the most prevalent disorders affecting gastrointestinal tract with a wide range of frequency around the world. In this study, we aimed to review all of the published studies about GERD's prevalence in Iran systematically.
  
  
  METHODS
  We searched bibliographic databases including PubMed and Google Scholar and local databases (Scientific Information Database and Iran Medex) to achieve all relevant articles to our subject and included them based on predefined inclusion criteria.
  
  
  RESULTS
  Twenty-two articles were included in the study to estimate the prevalence of GERD in Iran. Based on these articles, the prevalence of GERD in Iran was within the range of 1.9 to 52%.
  
  
  CONCLUSIONS
  Due to the differences between studies, such as characteristics of the sampled population and the diagnostic criteria, the reported prevalence of GERD was remarkably different in the reviewed studies. Nonetheless, because of the high prevalence of GERD in Iran, conducting large-scale epidemiological studies should be considered to determine factors associated with the prevalence of GERD to prevent and control it.
authors: Medical Students' Research Center, Isfahan University of Medical Sciences, Isfahan, India.
authors: Mohammadreza
authors: M
authors: Fazel
authors: Ammar Hassanzadeh
authors: AH
authors: Keshteli
authors: Pegah
authors: P
authors: Jahangiri
authors: Parnaz
authors: P
authors: Daneshpajouhnejad
authors: Peyman
authors: P
authors: Adibi