title: Glucocorticoid sensitivity of T-cell lymphoblastic leukemia/lymphoma is associated with glucocorticoid receptor-mediated inhibition of Notch1 expression.
authors: S
authors: S
authors: Cialfi
authors: R
authors: R
authors: Palermo
authors: S
authors: S
authors: Manca
authors: S
authors: S
authors: Checquolo
authors: D
authors: D
authors: Bellavia
authors: M
authors: M
authors: Pelullo
authors: R
authors: R
authors: Quaranta
authors: C
authors: C
authors: Dominici
authors: A
authors: A
authors: Gulino
authors: I
authors: I
authors: Screpanti
authors: C
authors: C
authors: Talora
mesh_terms: D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D051792:Basic Helix-Loop-Helix Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D015153:Blotting, Western; D047369:Chromatin Immunoprecipitation; D003907:Dexamethasone / Q000494:pharmacology*; D019008:Drug Resistance, Neoplasm / Q000235:genetics*; D018398:Homeodomain Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D009154:Mutation / Q000235:genetics; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D012333:RNA, Messenger / Q000235:genetics; D034741:RNA, Small Interfering / Q000235:genetics; D060888:Real-Time Polymerase Chain Reaction; D051881:Receptor, Notch1 / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D011965:Receptors, Glucocorticoid / Q000235:genetics / Q000378:metabolism*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D000072056:Transcription Factor HES-1; D014407:Tumor Cells, Cultured
chemical_list: D000893:Anti-Inflammatory Agents; D051792:Basic Helix-Loop-Helix Proteins; D003907:Dexamethasone; D018398:Homeodomain Proteins; D012333:RNA, Messenger; D034741:RNA, Small Interfering; D051881:Receptor, Notch1; D011965:Receptors, Glucocorticoid; D000072056:Transcription Factor HES-1; C497713:NR3C1 protein, human; C078493:HES1 protein, human