title: A model for educational simulation of the effect of oxytocin on uterine contractions.
abstract: Fetal oxygenation is sometimes compromised due to hyperstimulation of uterine contractions (UC) following labor augmentation with oxytocin. We present a model for educational simulation that incorporates the pharmacokinetic-pharmacodynamic properties of oxytocin, reproducing the effect of this drug on UC features. Six UC tracings were generated, reflecting different relevant situations. Three independent experts identified correctly the simulated situations in all tracings and attributed an average realism score of 9.4 (0-10). The model presented for simulation of the effect of oxytocin on UC provides sufficiently realistic results to be used in healthcare education and can easily be adapted to different patients and educational scenarios.
authors: Instituto de Engenharia Biomédica, Campus da FEUP, R. Dr. Roberto Frias, s/n, I305, 4200-465 Porto, Portugal.
authors: Mariana Fernandes
authors: MF
authors: Lobo
authors: Luísa Ferreira
authors: LF
authors: Bastos
authors: Willem L
authors: WL
authors: van Meurs
authors: Diogo
authors: D
authors: Ayres-de-Campos
mesh_terms: D004501:Education, Medical; D005260:Female; D006801:Humans; D008954:Models, Biological; D010121:Oxytocin / Q000493:pharmacokinetics / Q000494:pharmacology*; D011312:Pressure; D014590:Uterine Contraction / Q000187:drug effects*; D014599:Uterus / Q000187:drug effects / Q000502:physiology
chemical_list: D010121:Oxytocin