title: Detection and treatment of subclinical tuberculosis.
abstract: Reduction of active disease by preventive therapy has the potential to make an important contribution towards the goal of tuberculosis (TB) elimination. This report summarises discussions amongst a Working Group convened to consider areas of research that will be important in optimising the design and delivery of preventative therapies. The Working Group met in Cape Town on 26th February 2012, following presentation of results from the GC11 Grand Challenges in Global Health project to discover drugs for latent TB.
authors: Rapporteur, Imperial College London, MRC Centre for Molecular Bacteriology and Infection, Flowers Building, South Kensington Campus, London SW7 2AZ, UK. b.robertson@imperial.ac.uk
authors: Brian D
authors: BD
authors: Robertson
authors: Danny
authors: D
authors: Altmann
authors: Clif
authors: C
authors: Barry
authors: Bill
authors: B
authors: Bishai
authors: Stewart
authors: S
authors: Cole
authors: Thomas
authors: T
authors: Dick
authors: Ken
authors: K
authors: Duncan
authors: Chris
authors: C
authors: Dye
authors: Sabine
authors: S
authors: Ehrt
authors: Hanif
authors: H
authors: Esmail
authors: Joanne
authors: J
authors: Flynn
authors: Richard
authors: R
authors: Hafner
authors: Gray
authors: G
authors: Handley
authors: Willem
authors: W
authors: Hanekom
authors: Paul
authors: P
authors: van Helden
authors: Gilla
authors: G
authors: Kaplan
authors: Stefan H E
authors: SH
authors: Kaufmann
authors: Peter
authors: P
authors: Kim
authors: Christian
authors: C
authors: Lienhardt
authors: Valerie
authors: V
authors: Mizrahi
authors: Eric
authors: E
authors: Rubin
authors: Dirk
authors: D
authors: Schnappinger
authors: David
authors: D
authors: Sherman
authors: Jelle
authors: J
authors: Thole
authors: Omar
authors: O
authors: Vandal
authors: Gerhard
authors: G
authors: Walzl
authors: Digby
authors: D
authors: Warner
authors: Robert
authors: R
authors: Wilkinson
authors: Douglas
authors: D
authors: Young
mesh_terms: D000995:Antitubercular Agents / Q000008:administration & dosage*; D058491:Bacterial Load; D015415:Biomarkers; D015195:Drug Design; D005260:Female; D006801:Humans; D017589:Immunization Programs / Q000639:trends; D055985:Latent Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy*; D008297:Male; D023421:Models, Animal; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification* / Q000472:pathogenicity; D013019:South Africa; D014376:Tuberculosis / Q000517:prevention & control; D032581:Tuberculosis Vaccines / Q000008:administration & dosage* / Q000276:immunology
chemical_list: D000995:Antitubercular Agents; D015415:Biomarkers; D032581:Tuberculosis Vaccines