title: Efficacy of 5% imiquimod cream in a patient with classic Kaposi sarcoma.
abstract: BACKGROUND
  The classic Kaposi sarcoma is most common in the Mediterranean population over 50 years of age and presents with reddish-brown papules and nodules particularly on the lower limbs. Treatment depends on the clinical presentation and extension of lesions. Imiquimod is as an immune response modifier with antiangiogenic activity.
  
  
  METHODS
  We present a 74-year-old man with classic Kaposi sarcoma who had multiple, small, violaceous papules and nodules on the trunk and extremities with a history of 14 years. He complained particularly from plantar hyperkeratotic painful nodules. Treatment with imiquimod 5% cream under occlusion resulted with almost complete regression within 12 weeks. No local or systemic side effects were observed.
  
  
  CONCLUSIONS
  Topical imiquimod was a safe and effective therapy in our patient with classic Kaposi sarcoma.
authors: Department of Dermatology, Faculty of Medicine, Celal Bayar University, Manisa, Turkey.
authors: Kamer
authors: K
authors: Gündüz
authors: Umran
authors: U
authors: Günay
authors: Işıl
authors: I
authors: Inanir
authors: Gülsüm
authors: G
authors: Gençoğlan
authors: Peyker
authors: P
authors: Temiz