title: Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants.
abstract: Pregnane glycoside P57, the appetite suppressant component from Hoodia, was synthesized expeditiously, featuring preparation of the aglycone Hoodigogenin A from digoxin and assembly of the deoxytrisaccharide with glycosyl o-alkynylbenzoates as donors.
authors: State Key Laboratory of Bio-organic & Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
authors: Jian
authors: J
authors: Zhang
authors: Hefang
authors: H
authors: Shi
authors: Yuyong
authors: Y
authors: Ma
authors: Biao
authors: B
authors: Yu
mesh_terms: D029062:Apocynaceae / Q000737:chemistry*; D001067:Appetite Depressants / Q000138:chemical synthesis* / Q000737:chemistry; D010936:Plant Extracts / Q000138:chemical synthesis* / Q000737:chemistry; D012503:Saponins / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001067:Appetite Depressants; C471266:P57 compound; D010936:Plant Extracts; D012503:Saponins