title: [Drug chronotherapy: the coordination of biological rhythms with medical treatment].
abstract: Chronotherapy is defined as a coordination of biological rhythms with medical treatment. At present, several medications, including bronchodilating agents and H2 blockers, are administered with consideration for biological rhythms in routine clinical practice. In addition, recent studies have revealed that bedtime administration of antihypertensive medications can ameliorate the disturbed circadian rhythm of blood pressure and improve the prognosis in patients with hypertension. Because chronotherapy is a simple and inexpensive method of optimizing safe and effective pharmacotherapy, merits of this therapy should be evaluated in many medications.
authors: Division of Clinical Pharmacology, Department of Pharmacology, Jichi Medical University.
authors: Hitoshi
authors: H
authors: Ando
authors: Akio
authors: A
authors: Fujimura
mesh_terms: D000818:Animals; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use; D055870:Drug Chronotherapy; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents