title: Double CT imaging can measure the respiratory movement of small pulmonary tumors during stereotactic ablative radiotherapy.
abstract: OBJECTIVE
  The purpose of this study was to investigate the application of double CT imaging to measuring the respiratory movement of small pulmonary tumors during stereotactic ablative radiotherapy (SABR).
  
  
  METHODS
  A total of 122 small pulmonary tumors were measured in 45 patients. CT scans were conducted twice in all 122 tumors, once at the end of quiet inhalation and once at the end of exhalation. CT scans were conducted three times including at the end of quiet inhalation, at the end of exhalation and at free breathing in 36 tumors of 17 patients. The displacement of the tumor center in three directions was measured.
  
  
  RESULTS
  The 3D motion of 122 tumors was 10.10±7.16 mm. On average, the tumors moved 1.96±2.03 mm (rang, 0-9 mm) in the X direction, 5.19±4.69 mm (rang, 0-19 mm) in the Y direction, and 7.38±6.48 mm (rang, 0-26 mm) in the Z direction. The 3D motion of tumors in the lower lung (13.00±7.64 mm) was significantly greater than that in the upper lung (7.15±5.14 mm), P<0.01. The 3D motion of the lower left lung was 16.35±7.31 mm, which was significantly greater than that of the lower right lung (11.40±7.04 mm), P<0.05. Movement in the anterior lung in the Y direction was significantly larger than in the posterior lung. The motion was 7.49±5.43 mm and 4.04±3.82 mm respectively, P<0.01.
  
  
  CONCLUSIONS
  Double CT imaging provides accurate data for determining the outline of each target area during stereotactic ablative radiotherapy plane. The location of small pulmonary tumor foci was significantly affected by respiratory and cardiac motion.
authors: Ge
authors: G
authors: Shen
authors: Ying-Jie
authors: YJ
authors: Wang
authors: Hong-Guo
authors: HG
authors: Sheng
authors: Xiao-Ping
authors: XP
authors: Duan
authors: Jun-Liang
authors: JL
authors: Wang
authors: Wei-Jing
authors: WJ
authors: Zhang
authors: Zhen-Shan
authors: ZS
authors: Zhou
authors: Guang-Ying
authors: GY
authors: Zhu
authors: Ting-Yi
authors: TY
authors: Xia