title: Effects of body mass index on task-related oxygen uptake and dyspnea during activities of daily life in COPD.
abstract: BACKGROUND
  Patients with COPD use a higher proportion of their peak aerobic capacity during the performance of domestic activities of daily life (ADLs) compared to healthy peers, accompanied by a higher degree of task-related symptoms. To date, the influence of body mass index (BMI) on the task-related metabolic demands remains unknown in patients with COPD. Therefore, the aim of our study was to determine the effects of BMI on metabolic load during the performance of 5 consecutive domestic ADLs in patients with COPD.
  
  
  METHODS
  Ninety-four COPD patients and 20 healhty peers performed 5 consecutive, self-paced domestic ADLs putting on socks, shoes and vest; folding 8 towels; putting away groceries; washing up 4 dishes, cups and saucers; and sweeping the floor for 4 min. Task-related oxygen uptake and ventilation were assessed using a mobile oxycon, while Borg scores were used to assess task-related dyspnea and fatigue.
  
  
  RESULTS
  1. Relative task-related oxygen uptake after the performance of domestic ADLs was increased in patients with COPD compared to healthy elderly, whereas absolute oxygen uptake is similar between groups; 2. Relative oxygen uptake and oxygen uptake per kilogram fat-free mass were comparable between BMI groups; and 3. Borg symptom scores for dyspnea en fatigue were comparable between BMI groups.
  
  
  CONCLUSIONS
  Patients with COPD in different BMI groups perform self-paced domestic ADLs at the same relative metabolic load, accompanied by comparable Borg symptom scores for dyspnea and fatigue.
authors: Program Development Centre, CIRO +, Horn, The Netherlands. anoukvaes@ciro-horn.nl
authors: Anouk W
authors: AW
authors: Vaes
authors: Frits M E
authors: FM
authors: Franssen
authors: Kenneth
authors: K
authors: Meijer
authors: Martijn W J
authors: MW
authors: Cuijpers
authors: Emiel F M
authors: EF
authors: Wouters
authors: Erica P A
authors: EP
authors: Rutten
authors: Martijn A
authors: MA
authors: Spruit
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D015992:Body Mass Index; D016022:Case-Control Studies; D004417:Dyspnea / Q000503:physiopathology*; D017079:Exercise Tolerance; D005221:Fatigue; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism; D010101:Oxygen Consumption; D010641:Phenotype; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D010100:Oxygen