title: The role of microRNA in the response to cisplatin treatment.
abstract: Resistance to the cytotoxic effects of cisplatin can be mediated through changes in a wide variety of cellular processes and signalling pathways. The discovery of microRNAs as regulators of protein expression through the targeting of mRNA has led to a number of studies on the effect of cisplatin treatment on microRNA expression, and the ability of microRNAs to modulate cisplatin resistance.
authors: Institute for Cancer Studies, University of Sheffield Medical School, Sheffield, UK. r.m.drayton@sheffield.ac.uk
authors: Ross M
authors: RM
authors: Drayton
mesh_terms: D000818:Animals; D002945:Cisplatin / Q000627:therapeutic use*; D019008:Drug Resistance, Neoplasm / Q000235:genetics / Q000502:physiology*; D006801:Humans; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism*
chemical_list: D035683:MicroRNAs; D002945:Cisplatin