title: The untold story of Dabigatran etexilate: alveolar hemorrhage in an elderly patient with interstitial pulmonary fibrosis.
abstract: We report an 85-year-old male, with history of interstitial pulmonary fibrosis (IPF), who was presented with progressive dyspnea, hypoxia, and anemia of 2 months duration. Six months before presentation, the patient was placed on Dabigatran etexilate (Dabigatran) (110 mg BID) for atrial fibrillation. His prior anemia workup included a negative upper endoscopy and colonoscopy. Bronchoscopy revealed copious amounts of bloody secretions. The bronchial tree was washed and Dabigatran was discontinued. The patient's medical condition improved and was subsequently discharged home. Our case illustrates the failure of current literature to predict the isolated bronchoalveolar bleed secondary to Dabigatran therapy.
authors: Department of Internal Medicine, American University of Beirut-Medical Center, P.O. Box 11-0236, Riad El Solh, Beirut, 110 72020, Lebanon. ah51@aub.edu.lb
authors: Ahmad
authors: A
authors: Husari
authors: Atallah
authors: A
authors: Beydoun
authors: Amein
authors: A
authors: Sheik Ammar
authors: Joseph E
authors: JE
authors: Maakaron
authors: Ali
authors: A
authors: Taher
mesh_terms: D000369:Aged, 80 and over; D000740:Anemia / Q000188:drug therapy / Q000209:etiology; D000991:Antithrombins / Q000008:administration & dosage / Q000009:adverse effects*; D001281:Atrial Fibrillation / Q000188:drug therapy* / Q000209:etiology; D001562:Benzimidazoles / Q000008:administration & dosage / Q000009:adverse effects*; D000069604:Dabigatran; D004417:Dyspnea / Q000188:drug therapy / Q000209:etiology; D006470:Hemorrhage / Q000139:chemically induced* / Q000628:therapy; D006801:Humans; D008297:Male; D011650:Pulmonary Alveoli; D011658:Pulmonary Fibrosis / Q000150:complications / Q000188:drug therapy*; D015091:beta-Alanine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: D000991:Antithrombins; D001562:Benzimidazoles; D015091:beta-Alanine; D000069604:Dabigatran