title: Nickel-catalyzed diastereoselective alkyl-alkyl Kumada coupling reactions.
abstract: A nickel pincer complex is found to catalyze alkyl-alkyl Kumada coupling reactions of 1,3- and 1,4-substituted cyclohexyl halides and tetrahydropyrans with an excellent diastereoselectivity. The mechanistic investigation of the coupling reactions provides evidence that the activation of alkyl halides is reversible.
authors: Laboratory of Inorganic Synthesis and Catalysis, Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), SB-ISIC-LSCI, BCH 3305, Lausanne 1015, Switzerland.
authors: Pablo M
authors: PM
authors: Perez Garcia
authors: Thomas
authors: T
authors: Di Franco
authors: Alessio
authors: A
authors: Orsino
authors: Peng
authors: P
authors: Ren
authors: Xile
authors: X
authors: Hu