title: Tobacco use or body mass--do they predict tuberculosis mortality in Mumbai, India? Results from a population-based cohort study.
abstract: Tobacco use and under-nutrition are major public health concerns and tuberculosis is a major cause of morbidity and mortality in India. Using a cohort of 148,173 persons (recruited 1991-1997 and followed-up 1997-2003) the joint effects of tobacco use and BMI on tuberculosis mortality was studied. Tobacco use in any form and low-BMI had joint effect on tuberculosis mortality and the interaction effect was synergistic in men and antagonistic in women. Self-reported tuberculosis was associated with increased risk of tuberculosis mortality. In contrast, no such association was observed for self-reported diabetes persons. The risk pattern remained unchanged even after excluding tuberculosis deaths occurred within 1(st) two years of follow-up. This study highlights importance of age consideration of individual while excluding early deaths. Around 27% male tuberculosis deaths were attributable to their being underweight and smoker, while 22% male and 37% female deaths were attributable to their being underweight and smokeless tobacco user.
authors: Healis, Sekhsaria Institute for Public Health, CBD Belapur, India. pednekarmangesh@rediffmail.com
authors: Mangesh S
authors: MS
authors: Pednekar
authors: Matti
authors: M
authors: Hakama
authors: Prakash C
authors: PC
authors: Gupta
mesh_terms: D000328:Adult; D000367:Age Factors; D015992:Body Mass Index; D003920:Diabetes Mellitus / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D014029:Tobacco Use Disorder / Q000401:mortality*; D014376:Tuberculosis / Q000401:mortality*