title: Artifacts in amine analysis from anodic oxidation of organic solvents upon electrospray ionization for mass spectrometry.
abstract: Different phenylenediamines were used to explore anodic oxidation in solution during electrospray ionization (ESI) mass spectrometry analysis. In our experiments, a series of unknown ionic species was detected in the phenylenediamine solutions. Our results propose that reactions of phenylenediamines with species formed by anodic oxidation of typical ESI solvents during the electrospray ionization process such as formaldehyde are producing these peaks. Identification of these compounds inter alia suggests formal alkylation, a reaction not reported so far as a result of electrolytic oxidation in the prospective organic solvents.
authors: Institute of Analytical Chemistry, University of Leipzig, Germany.
authors: Ramarao
authors: R
authors: Abburi
authors: Stefan
authors: S
authors: Kalkhof
authors: Ramona
authors: R
authors: Oehme
authors: Andreas
authors: A
authors: Kiontke
authors: Claudia
authors: C
authors: Birkemeyer