title: Severe hypocalcemia complicated by postsurgical hypoparathyroidism and hungry bone syndrome in a patient with primary hyperparathyroidism, Graves' disease, and acromegaly.
abstract: We herein report a case of severe postsurgical hypocalcemia associated with primary hyperparathyroidism (pHPT), Graves' disease (GD) and acromegaly (AC). A 54-year-old woman was referred to our clinic for treatment of pHPT and GD. She also had active AC and was clinically diagnosed as multiple endocrine neoplasm type 1 because of pHPT and AC. Two enlarged parathyroid glands were detected by preoperative examinations. We performed total parathyroidectomy and thyroidectomy. After the operation, she showed severe hypocalcemia induced by postsurgical hypoparathyroidism and hungry bone syndrome. This is a rare case of postsurgical severe hypocalcemia associated with pHPT, GD and AC.
authors: Department of Endocrinology, Yamashita Thyroid and Parathyroid Clinic, Japan. sei.tac.thyroid@gmail.com
authors: Seigo
authors: S
authors: Tachibana
authors: Shinya
authors: S
authors: Sato
authors: Tadao
authors: T
authors: Yokoi
authors: Ryoko
authors: R
authors: Nagaishi
authors: Yuko
authors: Y
authors: Akehi
authors: Toshihiko
authors: T
authors: Yanase
authors: Hiroyuki
authors: H
authors: Yamashita
mesh_terms: D000172:Acromegaly / Q000150:complications*; D001851:Bone Diseases, Metabolic / Q000209:etiology*; D002118:Calcium / Q000378:metabolism; D005260:Female; D006111:Graves Disease / Q000150:complications* / Q000601:surgery*; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D006996:Hypocalcemia / Q000209:etiology* / Q000378:metabolism; D007011:Hypoparathyroidism / Q000209:etiology*; D008875:Middle Aged; D018761:Multiple Endocrine Neoplasia Type 1 / Q000150:complications / Q000601:surgery; D016105:Parathyroidectomy / Q000009:adverse effects; D011183:Postoperative Complications / Q000209:etiology*; D013965:Thyroidectomy / Q000009:adverse effects
chemical_list: D002118:Calcium