title: Transient severe non-proliferative retinopathy in an adolescent with type 1 diabetes and chronic myeloid leukemia.
abstract: The onset of diabetic retinopathy correlates with the long-term quality of glycemic control. A 17-yr-old adolescent with type 1 diabetes presented unexpectedly with acute non-proliferative retinopathy despite good glycemic control. Two months later chronic myeloid leukemia (CML) was diagnosed. Chemotherapy was initiated and within a few weeks the patient was in full remission concerning leukemia. Retinopathy completely resolved within 8 months. The patient was in good metabolic control throughout the course. To our knowledge, this is the first report of CML-triggered retinopathy in a well-controlled diabetic adolescent. In case of unexpected retinopathy in patients with type 1 diabetes, other potential causes of retinopathy should be considered.
authors: Department of Endocrinology and Diabetology, University Children's Hospital, Zurich, Switzerland. silvia.schmid@kispi.uzh.ch
authors: Silvia
authors: S
authors: Schmid
authors: Mariarosaria
authors: M
authors: Lang-Muritano
authors: Urs
authors: U
authors: Meier
authors: Riccardo
authors: R
authors: De Peron
authors: Daniel
authors: D
authors: Konrad
authors: Eugen
authors: E
authors: Schoenle
mesh_terms: D000293:Adolescent; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003930:Diabetic Retinopathy / Q000150:complications / Q000175:diagnosis; D003951:Diagnostic Errors; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D059545:Paraneoplastic Syndromes, Ocular / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D012074:Remission Induction; D012720:Severity of Illness Index