title: The effect of toll-like receptor 4 on macrophage cytokines during endotoxin induced uveitis.
abstract: Toll-like receptor 4 (TLR4) signal activation of macrophages can lead to endotoxin-induced uveitis (EIU). Previously, our research group has demonstrated a higher expression of TLR4 in vivo during EIU than normal. In this study, we analyzed levels of peritoneal macrophage cytokines from C3H/HeN mice with LPS stimulation in vitro to elucidate the effect of TLR4 on cytokines during EIU.
authors: Department of Ophthalmology, Chaoyang Hospital, Capital Medical University, No.8 Baijiazhuang Road, Chaoyang District, Beijing 100020, China.
authors: Shuo
authors: S
authors: Yang
authors: Department of Ophthalmology, Chaoyang Hospital, Capital Medical University, No.8 Baijiazhuang Road, Chaoyang District, Beijing 100020, China.
authors: Hong
authors: H
authors: Lu
authors: Department of Ophthalmology, Chaoyang Hospital, Capital Medical University, No.8 Baijiazhuang Road, Chaoyang District, Beijing 100020, China.
authors: Jing
authors: J
authors: Wang
authors: Department of Ophthalmology, Chaoyang Hospital, Capital Medical University, No.8 Baijiazhuang Road, Chaoyang District, Beijing 100020, China.
authors: Xin
authors: X
authors: Qi
authors: Department of Ophthalmology, Chaoyang Hospital, Capital Medical University, No.8 Baijiazhuang Road, Chaoyang District, Beijing 100020, China.
authors: Xuhui
authors: X
authors: Liu
authors: Department of Ophthalmology, Chaoyang Hospital, Capital Medical University, No.8 Baijiazhuang Road, Chaoyang District, Beijing 100020, China.
authors: Xiaolong
authors: X
authors: Zhang
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D008070:Lipopolysaccharides / Q000633:toxicity*; D017737:Macrophages, Peritoneal / Q000276:immunology* / Q000473:pathology; D008297:Male; D051379:Mice; D015846:Monokines / Q000276:immunology*; D051197:Toll-Like Receptor 4 / Q000276:immunology*; D014605:Uveitis / Q000139:chemically induced* / Q000276:immunology* / Q000473:pathology
chemical_list: D008070:Lipopolysaccharides; D015846:Monokines; C493487:Tlr4 protein, mouse; D051197:Toll-Like Receptor 4