title: Long-term dietary intake of selenium, calcium, and dairy products is associated with improved capillary recruitment in healthy young men.
abstract: OBJECTIVE
  To identify associations between long-term (1 year) food intake and skin nutritive microvascular function in healthy subjects.
  
  
  METHODS
  This was a cross-sectional study. A validated 88-item food-frequency questionnaire was administered to 39 healthy men aged 23.4 ± 0.5 years and body mass index 23.3 ± 2.3 kg/m², who reported food intake during the last year and underwent videocapillaroscopy exams. The main outcome was the increase in functional capillary recruitment, that is, peak capillary density after post-occlusive reactive hyperemia subtracted from basal capillary density (caps/mm²). Associations between reported food intake and functional capillary recruitment were investigated.
  
  
  RESULTS
  Daily average estimates of intake were: total energy (3,745 ± 1,365 kcal), carbohydrates (60.1 ± 5.9 %), lipids (22.1 ± 4.4 %), proteins (17.8 ± 4.1 %), fibers (33.9 ± 18.5 g), and cholesterol (492.8 ± 209.6 mg). Positive significant correlations with capillary recruitment were found for selenium (as μg/day/1,000 kcal; rho = 0.3412, p = 0.038,) calcium (as mg/day/1,000 kcal; rho = 0.3390, p = 0.043), and percentage of total energy from dairy products (rho = 0.3660, p = 0.023).
  
  
  CONCLUSIONS
  Long-term intakes of selenium, calcium, and dairy products were positively associated with capillary recruitment in skin nutritive microcirculation in healthy young men. The role of such dietary components is discussed and possible mechanisms for their effects should be further investigated. This evidence adds one more possible functional property of these nutrients and food items.
authors: Clinical and Experimental Research Laboratory on Vascular Biology, BioVasc, Biomedical Center, State University of Rio de Janeiro, Rua São Francisco Xavier, 524, Maracanã, UERJ, Pavilhão Haroldo Lisboa da Cunha, Sala 104 (BioVasc), Térreo, Rio de Janeiro, CEP, Brazil. nutri.carolinebuss@gmail.com
authors: Caroline
authors: C
authors: Buss
authors: Carolina
authors: C
authors: Marinho
authors: Priscila Alves
authors: PA
authors: Maranhão
authors: Eliete
authors: E
authors: Bouskela
authors: Luiz Guilherme
authors: LG
authors: Kraemer-Aguiar
mesh_terms: D000328:Adult; D001938:Brazil; D002136:Calcium, Dietary / Q000008:administration & dosage* / Q000378:metabolism / Q000627:therapeutic use; D002196:Capillaries / Q000254:growth & development* / Q000378:metabolism; D003430:Cross-Sectional Studies; D003611:Dairy Products; D004032:Diet; D002149:Energy Intake; D055951:Functional Food; D006801:Humans; D008297:Male; D008833:Microcirculation; D018919:Neovascularization, Physiologic; D012643:Selenium / Q000008:administration & dosage* / Q000378:metabolism / Q000627:therapeutic use; D012867:Skin / Q000098:blood supply* / Q000378:metabolism; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D002136:Calcium, Dietary; D012643:Selenium