title: New monoterpenes, diterpenes, and lignans from Abies recurvata.
abstract: From the aerial part of Abies recurvata, 62 miscellaneous chemical constituents were isolated including 6 new and 56 known ones. The new compounds comprised three monoterpenes, two diterpenes, and one lignan. Their chemical structures were characterized on the basis of various spectroscopic techniques. Dihydrodehydrodiconiferyl alcohol (35) showed the strongest inhibitory effects against lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells with an IC₅₀ value of 66.4 µM.
authors: School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.
authors: Yong-Li
authors: YL
authors: Li
authors: Ji-Gang
authors: JG
authors: Zhang
authors: Ping
authors: P
authors: Yu
authors: Bei-Lei
authors: BL
authors: Ke
authors: Ji
authors: J
authors: Ye
authors: Xian-Wen
authors: XW
authors: Yang
authors: Hui-Zi
authors: HZ
authors: Jin
authors: Wei-Dong
authors: WD
authors: Zhang
mesh_terms: D028202:Abies / Q000737:chemistry*; D000818:Animals; D045744:Cell Line, Tumor; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D017705:Lignans / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D008031:Lignin / Q000031:analogs & derivatives / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000009:adverse effects; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D009569:Nitric Oxide / Q000032:analysis / Q000378:metabolism; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D014315:Triterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D004224:Diterpenes; D017705:Lignans; D008070:Lipopolysaccharides; D039821:Monoterpenes; D010936:Plant Extracts; D014315:Triterpenes; C489718:pinonesinol; D009569:Nitric Oxide; D008031:Lignin