title: Splenomegaly and variceal bleeding in a ten-year-old HIV-infected girl with noncirrhotic portal hypertension.
abstract: Noncirrhotic portal hypertension is an uncommon liver disease of unknown origin, increasingly described in HIV-infected adults. Prolonged antiretroviral exposure, in particular to didanosine, and thrombophilic predisposition have been suggested as potential pathogenic factors. Data are limited in children. We describe a 10-year-old HIV-infected girl with noncirrhotic portal hypertension who presented with progressive spleen enlargement and variceal bleeding.
authors: Department of Pediatrics, L. Sacco Hospital, University of Milan, Italy.
authors: Vania
authors: V
authors: Giacomet
authors: Alessandra
authors: A
authors: Viganò
authors: Francesca
authors: F
authors: Penagini
authors: Valeria
authors: V
authors: Manfredini
authors: Giovanni
authors: G
authors: Maconi
authors: Mario
authors: M
authors: Camozzi
authors: Gian Vincenzo
authors: GV
authors: Zuccotti
mesh_terms: D002648:Child; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis*; D006470:Hemorrhage / Q000209:etiology*; D006651:Histocytochemistry; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications* / Q000175:diagnosis*; D011169:Portal Vein / Q000473:pathology; D013163:Splenomegaly / Q000150:complications* / Q000175:diagnosis*