title: Fabricating pH-stable and swellable very thin hyperbranched poly(ethylene imine)-oligosaccharide films fabricated without precoating: first view on protein adsorption.
abstract: For using successful (ultra)thin dendritic macromolecule films in (bio)sensing and microfluidic devices and for obtaining reproducible film properties, alteration effects arising from precoatings have to be avoided. Here, oligosaccharide-modified hyperbranched poly(ethylene imine)s (PEI-OS) were used to fabricate very thin PEI-OS films (15-20 nm in dry state), cross-linked with citric acid under condensation, and vacuum condition. However, no reactive precoating is necessary to obtain stable films, which allows very simple film preparation and avoids alteration of the PEIS-OS film properties arising from precoating. Several methods [(in situ) ellipsometry, AFM, XPS, (in situ) ATR-IR, streaming potential measurements] were applied to characterize homogeneity, surface morphology, and stability of these PEI-OS films between pH 2 and pH 10, but also the low protein adsorption behavior.
authors: Leibniz Institute of Polymer Research Dresden, 01069 Dresden, Germany.
authors: Monika
authors: M
authors: Warenda
authors: Anne
authors: A
authors: Richter
authors: Diana
authors: D
authors: Schmidt
authors: Andreas
authors: A
authors: Janke
authors: Martin
authors: M
authors: Müller
authors: Frank
authors: F
authors: Simon
authors: Ralf
authors: R
authors: Zimmermann
authors: Klaus-Jochen
authors: KJ
authors: Eichhorn
authors: Brigitte
authors: B
authors: Voit
authors: Dietmar
authors: D
authors: Appelhans
mesh_terms: D000327:Adsorption; D019343:Citric Acid / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D007097:Imines / Q000737:chemistry*; D009844:Oligosaccharides / Q000737:chemistry*; D011095:Polyethylenes / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism; D012822:Silicon Dioxide / Q000737:chemistry; D013499:Surface Properties
chemical_list: D007097:Imines; D009844:Oligosaccharides; D011095:Polyethylenes; D011506:Proteins; C505405:poly(ethylene imine); D019343:Citric Acid; D012822:Silicon Dioxide