title: Safety of living donor liver transplantation using older donors.
abstract: BACKGROUND
  There is limited information concerning older donors in living donor liver transplantation (LDLT). In the present study, we attempted to clarify whether it is safe to use older donors in LDLT.
  
  
  METHODS
  A total of 129 cases were reviewed in the present study. Donors and recipients were divided into group A (donors aged ≥ 50 y, n=21) and group B (donors aged <50 y, n=108). The pre-, intra-, and postoperative variables of the two groups were statistically compared.
  
  
  RESULTS
  Donors' complication rates were 38.10% and 28.70% for groups A and B, respectively (P=0.719). The overall 1-, 3-, and 5-y survival rates were 90%, 80%, and 66% for group A and 86%, 83%, and 75% for group B, respectively (P=0.573). Similar Clavien III or more complication rates for recipients were observed.
  
  
  CONCLUSIONS
  The present study suggested that LDLT using older donors had no negative influence on the outcomes of both donors and recipients.
authors: Division of Liver Transplantation, West China Hospital, Sichuan University, Chengdu, China.
authors: Chuan
authors: C
authors: Li
authors: Tian-Fu
authors: TF
authors: Wen
authors: Lu-Nan
authors: LN
authors: Yan
authors: Bo
authors: B
authors: Li
authors: Jia-Ying
authors: JY
authors: Yang
authors: Ming-Qing
authors: MQ
authors: Xu
authors: Wen-Tao
authors: WT
authors: Wang
authors: Yong-Gang
authors: YG
authors: Wei
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects / Q000401:mortality; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D015996:Survival Rate