title: A low-molecular-weight supramolecular hydrogel of riboflavin bolaamphiphile for VEGF-siRNA delivery.
abstract: A low-molecular-weight hydrogel derived from riboflavin (vitamin B(2)) that self-assembles to provide supramolecular nanofibers, biocompatible material, can be used to deliver VEGF-siRNA efficiently into human cells by the endocytosis pathway, where the siRNA is functionalized.
authors: Department of Chemistry, Division of IBB, Pohang University of Science and Technology, Pohang 790-784, Korea.
authors: Sachin Prakash
authors: SP
authors: Patil
authors: Hyun Seok
authors: HS
authors: Jeong
authors: Byeang Hyean
authors: BH
authors: Kim
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D004705:Endocytosis; D005663:Furans / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry*; D057139:Nanofibers / Q000737:chemistry / Q000648:ultrastructure; D011728:Pyridones / Q000737:chemistry*; D034741:RNA, Small Interfering / Q000235:genetics* / Q000378:metabolism; D012256:Riboflavin / Q000737:chemistry*; D014162:Transfection; D042461:Vascular Endothelial Growth Factor A / Q000235:genetics* / Q000378:metabolism
chemical_list: D001672:Biocompatible Materials; D005663:Furans; D011728:Pyridones; D034741:RNA, Small Interfering; D042461:Vascular Endothelial Growth Factor A; C543575:bolaamphiphile; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D012256:Riboflavin