title: Identification of Patients with Hepatitis C Virus Infection in Persons with Background of Intravenous Drug Use: The First Community Announcement-based Study From Iran.
abstract: OBJECTIVE
  Injection drug use plays the most important role in transmission of hepatitis C. In Iran, surveys have been conducted on various high risk groups but this is the first announcement based study for hepatitis C virus HCV prevalence among cases with history of intravenous drug using (IVDU) in the country.
  
  
  METHODS
  The announcement-based detection and follow-up of patients with anti-HCV positive project in volunteers with history of intravenous drug using was conducted in Isfahan province. At the first step, six focus groups were conducted and 2 pilot studies were carried out in two cities to design the main study. Comprehensive community announcement was done in all of public places and for physicians. The volunteers were invited to Isfahan reference laboratories and the serum samples were sent to Infectious Diseases Research Center Laboratory in standard conditions and HCV-Ab was tested by ELISA method.
  
  
  RESULTS
  In this study, 1,747 individuals that are estimated 50% of all expected intravenous drug users in the community were presented themselves. The most important reasons of success in recruiting volunteers in this study were the perfect propaganda, appropriate cooperation of lab staffs, continuous evaluation and good cooperation in Isfahan province administrations. HCV-Ab was detected in 34% of them and the HCV-Ab positives were sent for further follow-up procedures including confirmatory test, education, and treatment.
  
  
  CONCLUSIONS
  In spite of some limitations to select real cases, this study was considered as a successful experience. Compared to the surveys in Iran on HCV prevalence in intravenous drug users, the results of this study, which was based on volunteers by announcement seems to be noteworthy.
authors: Infectious Diseases and Tropical Medicine Research Center,  Isfahan University of Medical Sciences, Isfahan, Iran .
authors: Reza Fadaei
authors: RF
authors: Nobari
authors: Marjan
authors: M
authors: Meshkati
authors: Behrooz
authors: B
authors: Ataei
authors: Mohammad Reza
authors: MR
authors: Yazdani
authors: Kamal
authors: K
authors: Heidari
authors: Nazila
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authors: Kassaian
authors: Zary
authors: Z
authors: Nokhodian
authors: Parisa
authors: P
authors: Shoaei
authors: Majid
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authors: Yaran
authors: Peyman
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authors: Adibi