title: Ilelic acids A and B, two unusual triterpenes with a seven-membered ring from Ilex latifolia.
abstract: Two unusual triterpenes, ilelic acids A (1) and B (2), together with their biosynthetic related compounds ilelic acids C (3) and D (4) were isolated from the leaves of Ilex latifolia. Their structures with absolute configurations were elucidated by spectroscopic analysis and modified Mosher's method. The plausible biogenetic pathway of 1 and 2 is proposed. These triterpenes exhibited a potent inhibitory effect on MCF-7 and MDA-MB-231 cells.
authors: Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, People's Republic of China.
authors: Cun-Qin
authors: CQ
authors: Wang
authors: Lei
authors: L
authors: Wang
authors: Chun-Lin
authors: CL
authors: Fan
authors: Dong-Mei
authors: DM
authors: Zhang
authors: Xiao-Jun
authors: XJ
authors: Huang
authors: Ren-Wang
authors: RW
authors: Jiang
authors: Liang-Liang
authors: LL
authors: Bai
authors: Jun-Min
authors: JM
authors: Shi
authors: Ying
authors: Y
authors: Wang
authors: Wen-Cai
authors: WC
authors: Ye
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D005260:Female; D006801:Humans; D030017:Ilex / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014315:Triterpenes; C576445:ilelic acid A; C576444:ilelic acid B