title: Ru-catalyzed hydrogenation of 3,5-diketo amides: simultaneous control of chemo- and enantioselectivity.
abstract: By modulating the chelating priorities of the different directing groups in 3,5-diketo amides with the assistance from coordinating solvent, highly chemo- and enantioselective hydrogenation of the C3-carbonyls was achieved in the presence of [RuCl(benzene)(S)-SunPhos]Cl in THF.
authors: School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China.
authors: Wanfang
authors: W
authors: Li
authors: Weizheng
authors: W
authors: Fan
authors: Xin
authors: X
authors: Ma
authors: Xiaoming
authors: X
authors: Tao
authors: Xiaoming
authors: X
authors: Li
authors: Xiaomin
authors: X
authors: Xie
authors: Zhaoguo
authors: Z
authors: Zhang
mesh_terms: D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D004952:Esters; D006865:Hydrogenation; D012428:Ruthenium / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000577:Amides; D004952:Esters; D012997:Solvents; D012428:Ruthenium