title: Novel chitosan-based fluorescent materials for the selective detection and adsorption of Fe3+ in water and consequent bio-imaging applications.
abstract: A series of fluorescent materials were synthesized by modification of chitosan (CS) with 4-fluoresceincarboxaldehyde (Fluo) and N-methyl-carbazole-3-aldehyde (Cb). Both L-CS-Fluo and L-CS-Cb feature excellent water-solubility and exhibit highly selective fluorescence response to Fe(3+) in environment and biological fields. The high-molecular weight chitosan-based materials: H-CS-Fluo and H-CS-Cb take on doubled absorptivity compared to free chitosan due to the introduction of fluorescence probes. These modified-probe chitosan materials could be regenerated by treating with EDTA. Meanwhile, monomer probes AG-Fluo and AG-Cb linked by D-glucosamine were also synthesized to explore the binding efficiency.
authors: State Key Laboratory of Fine Chemicals, Dalian University of Technology, 2 Linggong Road, Dalian High-Tech Industrial Zone, Dalian 116024, China.
authors: Qingtao
authors: Q
authors: Meng
authors: Weiping
authors: W
authors: Su
authors: Cheng
authors: C
authors: He
authors: Chunying
authors: C
authors: Duan
mesh_terms: D000327:Adsorption; D048271:Chitosan / Q000737:chemistry*; D003124:Colorimetry; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D005470:Fluorometry; D005944:Glucosamine / Q000737:chemistry; D006801:Humans; D007501:Iron / Q000032:analysis* / Q000737:chemistry*; D061986:MCF-7 Cells; D057054:Molecular Imaging / Q000379:methods*; D014867:Water / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D014867:Water; D048271:Chitosan; D007501:Iron; D005944:Glucosamine