title: The effects of memantine on a patient having preclinical dementia with Lewy bodies.
abstract: OBJECTIVE
  Memantine has been reported to have positive effects on visual hallucinations and cognition in patients with dementia with Lewy bodies (DLB). We hypothesized that memantine would have similar effects on a patient having Charles Bonnet syndrome, preclinical DLB.
  
  
  METHODS
  We evaluated the effect of memantine on visual hallucination, cognitive abilities and so on from baseline to 4 months after the start of medication.
  
  
  RESULTS
  Treatment of the patient with memantine resulted in the disappearance of visual hallucinations but could not stop the progression to dementia.
  
  
  CONCLUSIONS
  Our results suggested that, for a patient having preclinical DLB, memantine had some degree of positive effects, but the mechanism remains to be revealed.
authors: Department of Psychiatry, Osaka General Medical Center, Osaka 558-8558, Japan. takayayan@gmail.com
authors: Masahiko
authors: M
authors: Takaya
authors: Kazuyo
authors: K
authors: Matsusaka
authors: Makoto
authors: M
authors: Yanagida
authors: Ryo
authors: R
authors: Kimura
authors: Hidenori
authors: H
authors: Matsunaga
mesh_terms: D000368:Aged; D000978:Antiparkinson Agents / Q000627:therapeutic use*; D060825:Cognitive Dysfunction / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006212:Hallucinations / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D020961:Lewy Body Disease / Q000150:complications / Q000188:drug therapy*; D008559:Memantine / Q000627:therapeutic use*; D062706:Prodromal Symptoms; D016896:Treatment Outcome
chemical_list: D000978:Antiparkinson Agents; D008559:Memantine