title: Regenerative endodontics and tissue engineering: what the future holds?
abstract: The work performed by researchers in regenerative endodontics and tissue engineering over the last decades has been superb; however, many questions remain to be answered. The basic biologic mechanisms must be elucidated that will allow the development of dental pulp and dentin in situ. Stress must be placed on the many questions that will lead to the design of effective, safe treatment options and therapies. This article discusses those questions, the answers to which may become the future of regenerative endodontics. The future remains bright, but proper support and patience are required.
authors: The Boston University Institute for Dental Research and Education, PO Box 505097, Dubai Healthcare City, Dubai, United Arab Emirates. harold.goodis@ucsf.edu
authors: Harold E
authors: HE
authors: Goodis
authors: Bassam Michael
authors: BM
authors: Kinaia
authors: Atheel M
authors: AM
authors: Kinaia
authors: Sami M A
authors: SM
authors: Chogle
mesh_terms: D003782:Dental Pulp / Q000503:physiopathology*; D004708:Endodontics / Q000379:methods*; D005544:Forecasting; D006801:Humans; D009805:Odontogenesis / Q000502:physiology*; D051880:Receptors, Notch / Q000502:physiology; D044968:Regenerative Medicine / Q000379:methods* / Q000639:trends; D013234:Stem Cells / Q000502:physiology*; D023822:Tissue Engineering / Q000379:methods* / Q000639:trends
chemical_list: D051880:Receptors, Notch