title: Model studies on the synthesis of madangamine alkaloids. Assembly of the macrocyclic rings.
abstract: Using simplified model derivatives, the assembly of the macrocyclic rings of madangamines, including the 13- and 14-membered D rings of madangamines C-E, the all-cis-triunsaturated 15-membered D ring of madangamine A, and the (Z,Z)-unsaturated 11-membered E ring common to madangamines A-E, has been studied.
authors: Laboratory of Organic Chemistry, Faculty of Pharmacy, and Institute of Biomedicine (IBUB), University of Barcelona, 08028-Barcelona, Spain.
authors: Stefano
authors: S
authors: Proto
authors: Mercedes
authors: M
authors: Amat
authors: Maria
authors: M
authors: Pérez
authors: Roberto
authors: R
authors: Ballette
authors: Federica
authors: F
authors: Romagnoli
authors: Andrea
authors: A
authors: Mancinelli
authors: Joan
authors: J
authors: Bosch
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D006576:Heterocyclic Compounds, 4 or More Rings; C508399:madangamine A