title: [Chronic kidney disease prevalence and trends (1998-2008) in an area of southern Italy. The data of the VIP project].
abstract: Chronic kidney disease (CKD) is a common disorder whose prevalence is increasing worldwide. In Italy the prevalence of CKD, especially the early stages, is still not exactly known. Our study examines the prevalence and trends in ten years (1200 subjects in 1998-1999 and 1200 subjects in 2008-2009) of the estimated glomerular filtration rate (eGFR) in a population of southern Italy. We analyzed, within the VIP project, the prevalence of CKD (eGFR <60) in our area and its relationship to diabetes and hypertension as well as the trend between the years 1998-1999 and 2008-2009. The estimate of the GFR was obtained with the Cockcroft-Gault formula corrected for body surface area. The prevalence of CKD, stratified by the population of Campania, was about 5.9% in males and 3.9% in females in the years 1998-1999; ten years later (2008-2009) it had increased to 6.2% in males and 4.5% in females. The differences between males and females and between the two decades are not statistically significant although the trend shows a clear increase in subjects affected by CKD among both sexes. Among the male population the prevalence of CKD in persons with hypertension or diabetes, in those with both diseases, and in those free from these diseases was 11.2%, 12%, 13.8% and 6.3% (p=0.018), respectively. The same groups among females showed a CKD prevalence of 8%, 9.2%, 9.7% and 4.4%, respectively (p=0.042). Our work provides a picture of the prevalence of CKD in an area of southern Italy. It highlights the increase in CKD and calls upon a greater use of renal function tests in clinical practice, so that individuals at increased risk of developing cardiovascular complications may be detected as early as possible.
authors: Unita' Operativa di Cardiologia e UTIC, Ospedale Amico ''G. Fucito'' di Mercato S. Severino - Azienda Ospedaliera Universitaria Integrata di Salerno, Italy. capuanov@tiscali.it
authors: Vincenzo
authors: V
authors: Capuano
authors: Norman
authors: N
authors: Lamaida
authors: Maria Immacolata
authors: MI
authors: Borrelli
authors: Ernesto
authors: E
authors: Capuano
authors: Antonio
authors: A
authors: Fasolino
authors: Eduardo
authors: E
authors: Capuano
authors: Matteo
authors: M
authors: Sonderegger
authors: Rocco
authors: R
authors: Capuano
authors: Vincenzo
authors: V
authors: Citro
authors: Fabio
authors: F
authors: Franculli
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology*; D013997:Time Factors