title: piRNAs and siRNAs collaborate in Caenorhabditis elegans genome defense.
abstract: Caenorhabditis elegans piRNAs promote genome surveillance by triggering siRNA-mediated silencing of nonself DNA in competition with licensing programs that support endogenous gene expression.
authors: Allison C
authors: AC
authors: Billi
authors: Mallory A
authors: MA
authors: Freeberg
authors: John K
authors: JK
authors: Kim
mesh_terms: D000818:Animals; D060565:Argonaute Proteins / Q000378:metabolism; D017173:Caenorhabditis elegans / Q000235:genetics* / Q000378:metabolism; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism; D004251:DNA Transposable Elements; D044127:Epigenesis, Genetic; D049751:Genome, Helminth; D034741:RNA, Small Interfering / Q000378:metabolism*
chemical_list: D060565:Argonaute Proteins; D029742:Caenorhabditis elegans Proteins; D004251:DNA Transposable Elements; D034741:RNA, Small Interfering