title: Experimental model of facial paralysis by nerve compression in primates (Callithrix sp.): a new model of facial paralysis in small nonhuman primates.
abstract: CONCLUSIONS
  We conclude that facial nerve injury induced by compression is associated with a reasonable time window (4 weeks) that allows possible neurotrophic effects to be analyzed. Additionally, there are no hints of cross-innervation by the contralateral facial nerve or parallel innervation by other nerves in the hemiface ipsilateral to the injured nerve.
  
  
  OBJECTIVE
  The aim of this work was to develop an experimental model of facial nerve injury in nonhuman primates (Callithrix sp.).
  
  
  METHODS
  In this study, individuals of the non-human primate species Callithrix sp. were subjected to three different types of facial nerve injury, and they were observed for 27 days after surgery by video to record their facial movements.
  
  
  RESULTS
  Two types of nerve compression caused severe initial facial paralysis followed by gradual recovery until normal levels were reached at the end of the evaluation period. Injury induced by nerve resection was followed by a complete lack of facial movement recovery.
authors: Otorhinolaryngology and Head and Neck Surgery Department, Federal University of SãoPaulo/UNIFESP, São Paulo, Brazil.
authors: Felipe Costa
authors: FC
authors: Neiva
authors: Andrei
authors: A
authors: Borin
authors: Simone
authors: S
authors: Cinini
authors: Luiz Eugênio A M
authors: LE
authors: Mello
authors: Oswaldo Laércio M
authors: OL
authors: Cruz
authors: José Ricardo G
authors: JR
authors: Testa
mesh_terms: D000818:Animals; D002144:Callithrix; D004195:Disease Models, Animal; D020220:Facial Nerve Injuries; D005158:Facial Paralysis; D005260:Female; D008297:Male