title: Early juvenile idiopathic arthritis.
abstract: Early juvenile idiopathic arthritis (JIA) is important to recognize as timely diagnosis and treatment improves prognosis. It is a misconception that complications of JIA arise only from long-standing disease and that children will outgrow it. Early aggressive treatment is the paradigm as early disease activity has long-term consequences. There are predictors of persistent disease and joint erosions that may identify patients at higher risk. Control of disease activity within the first 6 months of onset confers improved clinical course and outcomes. The treatment perspective is thus one of early aggressive treatment for induction of disease control and ultimately remission.
authors: Division of Rheumatology, Children's Hospital Los Angeles, Keck School of Medicine of USC, 4650 Sunset Boulevard, MS#60, Los Angeles, CA 90027, USA. kmarzan@chla.usc.edu
authors: Katherine Anne B
authors: KA
authors: Marzan
authors: Bracha
authors: B
authors: Shaham
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D018450:Disease Progression; D042241:Early Diagnosis; D006801:Humans; D007596:Joints / Q000473:pathology / Q000503:physiopathology; D011379:Prognosis; D055502:Secondary Prevention; D012720:Severity of Illness Index
chemical_list: D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents