title: Time-gated luminescence microscopy with responsive nonmetal probes for mapping activity of protein kinases in living cells.
abstract: A photoluminescence probe ARC-1185, possessing both high affinity towards basophilic protein kinases (PKs) and microsecond-scale luminescence lifetime when associated with a kinase, was used for the mapping of ARC-1185-PK complexes in living cells with time-gated luminescence microscopy.
authors: Institute of Chemistry, University of Tartu, 14A Ravila St., 50411 Tartu, Estonia.
authors: Angela
authors: A
authors: Vaasa
authors: Kadri
authors: K
authors: Ligi
authors: Shabnam
authors: S
authors: Mohandessi
authors: Erki
authors: E
authors: Enkvist
authors: Asko
authors: A
authors: Uri
authors: Lawrence W
authors: LW
authors: Miller
mesh_terms: D000818:Animals; D001491:Basophils / Q000201:enzymology; D004285:Dogs; D005456:Fluorescent Dyes / Q000737:chemistry*; D061985:Madin Darby Canine Kidney Cells; D008856:Microscopy, Fluorescence; D009842:Oligopeptides / Q000737:chemistry*; D011494:Protein Kinases / Q000737:chemistry / Q000378:metabolism*; D013997:Time Factors; D014466:Ultraviolet Rays
chemical_list: C576481:ARC-1185; D005456:Fluorescent Dyes; D009842:Oligopeptides; D011494:Protein Kinases