title: Cyclical variation in the incidence of childhood type 1 diabetes in Western Australia (1985-2010).
abstract: OBJECTIVE
  To examine the incidence of childhood type 1 diabetes in Western Australia from 1985-2010.
  
  
  METHODS
  Incidence rates were calculated for children aged 0-14 years and were analyzed by calendar year, sex, and age at diagnosis.
  
  
  RESULTS
  There were 1,873 cases, and the mean incidence was 18.1/100,000 person-years (95% CI: 17.5-19.2). The incidence increased by 2.3% a year (1.6-2.9%) with a sinusoidal 5-year cyclical variation of 14% (7-22%). The lowest rate of increase in incidence was observed in 0-4-year-olds.
  
  
  CONCLUSIONS
  The cyclical pattern in incidence observed supports the role of environmental factors in childhood type 1 diabetes.
authors: Department of Endocrinology and Diabetes, Princess Margaret Hospital, Perth, Western Australia, Australia.
authors: Aveni
authors: A
authors: Haynes
authors: Max K
authors: MK
authors: Bulsara
authors: Carol
authors: C
authors: Bower
authors: Timothy W
authors: TW
authors: Jones
authors: Elizabeth A
authors: EA
authors: Davis
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D014904:Western Australia / Q000453:epidemiology