title: Human papillomavirus infection in Brazilian women with  normal cervical cytology.
abstract: We examined the prevalence of human papillomavirus  (HPV) infection in a sample of Brazilian women presenting normal cervical  cytology. Possible interactions between patient characteristics and HPV  infection were analyzed in order to provide background data to improve cervical  cancer screening and prophylaxis. Cervical samples of 399 women, received for  routine evaluation in the Health Department of Ouro Preto, MG, Brazil, were  subjected to HPV-DNA testing by PCR with MY09/11 primers. HPV-positive  specimens were typed by RFLP. A structured epidemiological questionnaire was  administered to each woman. HPV prevalence among these cytologically normal  women was 11%. Twelve viral types were detected, the most common being HPV-16,  -6, -61, -83, and -66. HPV was more prevalent in younger women; high-risk viral  types were detected in 61% of the infected women and 27% of the infected women  had multiple HPV infections. Significant associations of HPV infection were  found with age, literacy, residence, marital status, lifetime number of sexual  partners, and parity. We detected a great diversity of HPV types in women with  normal cytology. This kind of information about local populations is useful for  HPV prevention and vaccination strategies.
authors: Laboratório de Genética, Departamento de Genética, Instituto Butantan, São Paulo, SP, Brasil.
authors: P M
authors: PM
authors: Miranda
authors: B C V
authors: BC
authors: Pitol
authors: M S
authors: MS
authors: Moran
authors: N N T
authors: NN
authors: Silva
authors: P M
authors: PM
authors: Felix
authors: J L
authors: JL
authors: Lima-Filho
authors: C M
authors: CM
authors: Carneiro
authors: I D C G
authors: ID
authors: Silva
authors: R F
authors: RF
authors: Carvalho
authors: A A
authors: AA
authors: Lima
authors: W
authors: W
authors: Beçak
authors: R C
authors: RC
authors: Stocco
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002584:Cervix Uteri / Q000473:pathology* / Q000821:virology; D005260:Female; D052162:Human papillomavirus 16 / Q000235:genetics*; D052163:Human papillomavirus 6 / Q000235:genetics*; D006801:Humans; D008875:Middle Aged; D015999:Multivariate Analysis; D030361:Papillomavirus Infections / Q000453:epidemiology / Q000473:pathology* / Q000821:virology; D015995:Prevalence; D014626:Vaginal Smears; D055815:Young Adult