title: Determination of the absolute configuration of 19-OH-(-)-eburnamonine using a combination of residual dipolar couplings, DFT chemical shift predictions, and chiroptics.
abstract: 19-OH-(-)-eburnamonine 1 is a new indole alkaloid isolated from Bonafusia macrocalyx. A natural derivative from (-)-eburnamonine for which absolute configuration and conformation has been determined by making use of residual dipolar couplings enhanced NMR, circular dichroism spectra and high-level computations.
authors: Departamento de Química Orgánica, Universidade de Vigo, 36310 Vigo, Spain.
authors: Pablo
authors: P
authors: Trigo-Mouriño
authors: Roxana
authors: R
authors: Sifuentes
authors: Armando
authors: A
authors: Navarro-Vázquez
authors: Chakicherla
authors: C
authors: Gayathri
authors: Helena
authors: H
authors: Maruenda
authors: Roberto R
authors: RR
authors: Gil
mesh_terms: D008958:Models, Molecular; D008968:Molecular Conformation; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D014748:Vinca Alkaloids / Q000737:chemistry*
chemical_list: D014748:Vinca Alkaloids; C016422:eburnamonine