title: Villarinol, a new alkenoyloxyalkenol derivative from the endemic Philippine Rubiaceae species Villaria odorata.
abstract: Villarinol (1), a new alkenoyloxy alkenol metabolite, has been isolated from the dichloromethane extract of Villaria odorata, an endemic Rubiaceae Philippine plant, along with the known compounds stigmasterol and 4-hydroxybenzaldehyde. The structure of 1 was elucidated on the basis of spectroscopic and spectrometric studies. The extracts of V. odorata exhibited moderate inhibition against Mycobacterium tuberculosis H37Rv, based on the colorimetric microplate alamar blue assay.
authors: Phytochemistry and Organic Synthesis Laboratory, Research Center for the Natural and Applied Sciences, University of Santo Tomas, Espana, Manila 1015, Philippines. allanpatrick_m@yahoo.com
authors: Allan Patrick G
authors: AP
authors: Macabeo
authors: Jalil A
authors: JA
authors: Avila
authors: Grecebio Jonathan D
authors: GJ
authors: Alejandro
authors: Scott G
authors: SG
authors: Franzblau
authors: Simeon F
authors: SF
authors: Kouam
authors: Hidayat
authors: H
authors: Hussain
authors: Karsten
authors: K
authors: Krohn
mesh_terms: D000995:Antitubercular Agents / Q000737:chemistry / Q000494:pharmacology; D001547:Benzaldehydes / Q000737:chemistry / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D019666:Rubiaceae / Q000737:chemistry*; D013265:Stigmasterol / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000995:Antitubercular Agents; D001547:Benzaldehydes; D010936:Plant Extracts; D013265:Stigmasterol; C011483:4-hydroxybenzaldehyde