title: Exposure to residential radon and lung cancer in never-smokers: the preliminary results of the LCRINS study.
abstract: OBJECTIVE
  Residential radon is the second most important risk factor for lung cancer and the first among never-smokers. The objective of this study is to report the concentrations of residential radon in a series of never-smoker cases recruited in a multicenter study of cases and controls in northwestern Spain. In this study, all the hospitals in the Spanish province of Galicia and one from Asturias participated.
  
  
  METHODS
  The present article includes a series of cases with residential radon measurements. All the subjects were personally interviewed, 3 ml of blood were taken from each, and they were each given instructions about how to place a residential radon detector in their homes.
  
  
  RESULTS
  Sixty-nine case subjects were recruited, 84% of whom were women with a mean age of 71, and 81% of whom had adenocarcinoma. The average concentration of residential radon in the cases was 237 Bq/m(3), while the average concentration in the Galician population is 79 Bq/m(3). No relationship was observed between the concentration of residential radon and either sex or age at the time of diagnosis of the cases, but there was a tendency towards having a greater concentration in those diagnosed with small-cell and large-cell carcinoma.
  
  
  CONCLUSIONS
  The concentrations of residential radon in the cases included are very high at about three times the average concentration of residential radon to which the general population of Galicia is exposed.
authors: Área de Medicina Preventiva y Salud Pública, Universidad de Santiago de Compostela, Santiago de Compostela, La Coruña, Spain. alberto.ruano@usc.es
authors: Alberto
authors: A
authors: Ruano-Ravina
authors: Luciana
authors: L
authors: Prini-Guadalupe
authors: Juan Miguel
authors: JM
authors: Barros-Dios
authors: José
authors: J
authors: Abal-Arca
authors: Virginia
authors: V
authors: Leiro-Fernández
authors: Ana Isabel
authors: AI
authors: González-Silva
authors: Antonio
authors: A
authors: Golpe-Gómez
authors: Francisco Javier
authors: FJ
authors: González-Barcala
authors: Carolina
authors: C
authors: Pena
authors: Carmen
authors: C
authors: Montero-Martínez
authors: Cristina
authors: C
authors: Martínez-González
authors: María José
authors: MJ
authors: Mejuto-Martí
authors: Alejandro
authors: A
authors: Veres-Racamonde
mesh_terms: D000230:Adenocarcinoma / Q000453:epidemiology / Q000209:etiology; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D018287:Carcinoma, Large Cell / Q000453:epidemiology / Q000209:etiology; D002289:Carcinoma, Non-Small-Cell Lung / Q000453:epidemiology / Q000209:etiology; D018288:Carcinoma, Small Cell / Q000453:epidemiology / Q000209:etiology; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000209:etiology; D016022:Case-Control Studies; D004307:Dose-Response Relationship, Radiation; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006798:Housing; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology / Q000209:etiology*; D011834:Radiation Monitoring; D011886:Radon / Q000009:adverse effects* / Q000032:analysis; D017678:Sex Distribution; D013030:Spain / Q000453:epidemiology
chemical_list: D011886:Radon