title: Systematic review and meta-analysis on heavy and lightweight polypropylene mesh in Lichtenstein inguinal hernioplasty.
abstract: BACKGROUND
  Recurrence and pain are the two most important outcomes after inguinal hernia surgery. The concept of lightweight or partially absorbable macroporous meshes was developed under the assumption that the observed pain rate could be decreased without increasing the number of recurrences. Few randomized trials were published to analyze their clinical value, and some concern was raised because of an increased risk of recurrence. A systematic review and a meta-analysis of RCTs were carried out to determine whether the use of lightweight meshes influenced the pain and recurrence rate after Lichtenstein hernioplasty.
  
  
  METHODS
  To assess the value of the lightweight mesh, an extensive literature search was performed. The random-effect meta-analysis model was used to correct for clinical diversity and methodological variations between studies. Recurrence rate, aspects of chronic pain and foreign body feeling at 6-60 months postoperatively were assessed.
  
  
  RESULTS
  Eight prospective RCTs of good quality were identified. Analysis demonstrated no significant difference regarding recurrence (OR, 1.11; 95 % CI, 0.57-2.14; p = 0.77). No significant difference was observed concerning severe pain (OR, 0.99; 95 % CI, 0.48-2.02; p = 0.97). Description of any pain resulted in a significant improvement in the lightweight group (OR, 0.65; 95 % CI, 0.50-0.84; p = 0.001). The presence of foreign body feeling was favoring the lightweight group (OR, 0.62; 95 % CI, 0.41-0.94; p = 0.02).
  
  
  CONCLUSIONS
  The use of lightweight mesh did not neither increase the recurrence rate nor reduce the incidence of severe pain. A significant reduction in foreign body feeling and overall pain rate in the postoperative period was recorded. Lightweight meshes could be considered as a material of choice in primary inguinal hernioplasty.
authors: Department of General and Vascular Surgery, Ceynowa Hospital in Wejherowo, ul Jagalskiego 10, 84-200, Wejherowo, Poland. smietanski@herniaweb.org
authors: M
authors: M
authors: Śmietański
authors: I A
authors: IA
authors: Śmietańska
authors: A
authors: A
authors: Modrzejewski
authors: M P
authors: MP
authors: Simons
authors: T J
authors: TJ
authors: Aufenacker
mesh_terms: D059350:Chronic Pain / Q000209:etiology; D005547:Foreign Bodies / Q000150:complications; D006552:Hernia, Inguinal / Q000601:surgery*; D059685:Herniorrhaphy / Q000009:adverse effects; D006801:Humans; D010149:Postoperative Pain / Q000209:etiology; D011126:Polypropylenes / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D012008:Recurrence; D012677:Sensation; D013526:Surgical Mesh / Q000009:adverse effects
chemical_list: D011126:Polypropylenes