title: Isolation and characterization of new ceramides from aerial parts of Lepidaploa cotoneaster.
abstract: Two new ceramides were isolated from the bulbs of Lepidaploa cotoneaster (Willd. ex Spreng.) H. Rob. [Vernonia cotoneaster (Willd. ex Spreng.) Less.)], in addition to germanicol, beta-sitosterol, stigmasterol, 3-beta-O-beta-D-glucopyranosyl-sitosterol, lupeol, lupeoyl acetate and tiliroside. The structures of the new compounds were elucidated by spectral techniques (MS, 1H NMR, 13C NMR, HSQC, HMBC, DEPT, and TOCSY) and were compared with data reported in literature, and were established as 2S*,2'R*,3S*,4R*,11E)-N-[2'-hydroxyhenicosanoyl]-2-amino-nonadec-11-ene-1,3,4-triol (1) and (2S*,2'R*,3S*,4R*,8E)-N-[2'-hydroxytricosanoyl]-2-amino-nonadec-8-ene-1,3,4-triol (2). To establish the structure and to locate the double bond, the methyl ester of the fatty acid and dimethyl disulfide (DMDS) derivatives were prepared for both ceramides.
authors: Instituto de Química, Universidade Federal da Bahia, Campus de Ondina, Salvador (BA), Brazil 40170290.
authors: Edlene O
authors: EO
authors: dos Santos
authors: Marilena
authors: M
authors: Meira
authors: Ademir E
authors: AE
authors: do Vale
authors: Jorge M
authors: JM
authors: David
authors: Luciano P
authors: LP
authors: de Queiróz
authors: Juceni P
authors: JP
authors: David
mesh_terms: D002518:Ceramides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry*; D027824:Rosaceae / Q000737:chemistry*
chemical_list: D002518:Ceramides