title: Familial Takayasu arteritis in a mother and daughter. A report of two cases.
abstract: Takayasu arteritis (TA) is a chronic granulomatous panarteritis, predominantly affecting the aorta and its main branches. Infections, genetic factors as suggested by familial clustering, and autoimmunity may play a role in its pathogenesis. In this report, we describe familial TA in a mother and daughter with diverse clinical manifestations. In addition to being a familial form of vasculitis, both of our cases demonstrated amyloidosis, chronic renal disease thought to be due to ischemic nephropathy, and hypertensive nephrosclerosis.
authors: Department of Cardiology, Faculty of Medicine, Çukurova University, Adana, Turkey. alideniz78@gmail.com
authors: A
authors: A
authors: Deniz
authors: F
authors: F
authors: Yildiz
authors: H
authors: H
authors: Aktas
authors: G I
authors: GI
authors: Berk
authors: E
authors: E
authors: Erken
authors: M
authors: M
authors: Demirtas
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000151:congenital* / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D009679:Nuclear Family; D051436:Renal Insufficiency, Chronic / Q000151:congenital* / Q000175:diagnosis*; D013625:Takayasu Arteritis / Q000151:congenital* / Q000175:diagnosis*