title: Dental stem cells and their sources.
abstract: The search for more accessible mesenchymal stem cells than those found in bone marrow has propelled interest in dental tissues. Human dental stem/progenitor cells (collectively termed dental stem cells [DSCs]) that have been isolated and characterized include dental pulp stem cells, stem cells from exfoliated deciduous teeth, stem cells from apical papilla, periodontal ligament stem cells, and dental follicle progenitor cells. Common characteristics of these cell populations are the capacity for self-renewal and the ability to differentiate into multiple lineages. In vitro and animal studies have shown that DSCs can differentiate into osseous, odontogenic, adipose, endothelial, and neural-like tissues.
authors: Department of Endodontology, School of Dentistry, Oregon Health and Science University, 611 Southwest Campus Drive, Portland, OR 97239, USA. sedgley@ohsu.edu
authors: Christine M
authors: CM
authors: Sedgley
authors: Tatiana M
authors: TM
authors: Botero
mesh_terms: D002454:Cell Differentiation / Q000502:physiology*; D019070:Cell Lineage; D003771:Dental Papilla / Q000166:cytology; D003782:Dental Pulp / Q000166:cytology; D003795:Dental Sac / Q000166:cytology; D048091:Guided Tissue Regeneration; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000502:physiology; D010513:Periodontal Ligament / Q000166:cytology; D039904:Pluripotent Stem Cells