title: Clinical application of cine-MRI in the visual assessment of mitral regurgitation compared to echocardiography and cardiac catheterization.
abstract: BACKGROUND
  Detecting and quantifying the severity of mitral regurgitation is essential for risk stratification and clinical decision-making regarding timing of surgery. Our objective was to assess specific visual parameters by cine-magnetic resonance imaging (MRI) in the determination of the severity of mitral regurgitation and to compare it to previously validated imaging modalities: echocardiography and cardiac ventriculography.
  
  
  METHODS
  The study population consisted of 68 patients who underwent a cardiac MRI followed by an echocardiogram within a median time of 2.0 days and 49 of these patients who had a cardiac catheterization, median time of 2.0 days. The inter-rater agreement statistic (Kappa) was used to evaluate the agreement.
  
  
  RESULTS
  There was moderate agreement between cine MRI and Doppler echocardiography in assessing mitral regurgitation severity, with a kappa value of 0.47, confidence interval (CI) 0.29-0.65. There was also fair agreement between cine MRI and cardiac catheterization with a kappa value of 0.36, CI of 0.17-0.55.
  
  
  CONCLUSIONS
  Cine MRI offers a reasonable alternative to both Doppler echocardiography and, to a lesser extent, cardiac catheterization for visually assessing the severity of mitral regurgitation with specific visual parameters during routine clinical cardiac MRI.
authors: Department of Medicine, Division of Cardiology, New York Methodist Hospital, Brooklyn, New York, United States of America. John.Heitner@gmail.com
authors: John
authors: J
authors: Heitner
authors: Geetha P
authors: GP
authors: Bhumireddy
authors: Anna Lisa
authors: AL
authors: Crowley
authors: Jonathan
authors: J
authors: Weinsaft
authors: Salman A
authors: SA
authors: Haq
authors: Igor
authors: I
authors: Klem
authors: Raymond J
authors: RJ
authors: Kim
authors: James G
authors: JG
authors: Jollis
mesh_terms: D006328:Cardiac Catheterization; D015150:Echocardiography, Doppler; D005260:Female; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D009929:Organ Size; D012189:Retrospective Studies; D013318:Stroke Volume; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging