title: Pregnancy outcome in anti-N-methyl-D-aspartate receptor encephalitis.
abstract: BACKGROUND
  Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune disorder resulting in neurologic and psychiatric symptoms. Treatment is challenging in pregnancy, because little data exist to guide management.
  
  
  METHODS
  A 24-year-old woman with a known diagnosis of anti-NMDA receptor encephalitis using intravenous immunoglobulin therapy became pregnant. Her pregnancy was uncomplicated with no relapses. She delivered at 35 4/7 weeks of gestation after having preterm premature rupture of membranes. She had a relapse of symptoms after delivery.
  
  
  CONCLUSIONS
  This patient with anti-NMDA receptor encephalitis had an uneventful pregnancy with overall good outcome; however, she experienced relapse soon after delivery. This disease may mimic other autoimmune diseases, with improvement during pregnancy and risk for relapse postpartum.
authors: From the Departments of Obstetrics/Gynecology, Family Medicine, and Neurology and the Division of Maternal Fetal Medicine, University of California, Davis Medical Center, and the VA Northern California Health Care System, Sacramento, California.
authors: Joseph
authors: J
authors: Magley
authors: Dena
authors: D
authors: Towner
authors: Véronique
authors: V
authors: Taché
authors: Michelle L
authors: ML
authors: Apperson
mesh_terms: D000328:Adult; D060426:Anti-N-Methyl-D-Aspartate Receptor Encephalitis / Q000175:diagnosis*; D001327:Autoimmune Diseases / Q000175:diagnosis*; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000209:etiology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D007231:Infant, Newborn; D007234:Infant, Premature; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D012008:Recurrence; D055815:Young Adult
chemical_list: D016756:Immunoglobulins, Intravenous