title: Mycobacterium tuberculosis modulators of the macrophage's cellular events.
abstract: A number of mycobacterial macromolecules have been shown to target biological processes within host macrophages; however, the exact mechanism for the majority of these host-pathogen interactions is poorly understood. The following review summarizes current knowledge and expands on a subset of mycobacterial effectors for which a cognate substrate, cellular partner or signaling pathway have been experimentally identified within the human host.
authors: Division of Infectious Diseases, Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
authors: Valérie
authors: V
authors: Poirier
authors: Yossef
authors: Y
authors: Av-Gay
mesh_terms: D017951:Antigen Presentation; D001426:Bacterial Proteins / Q000276:immunology / Q000378:metabolism*; D054884:Host-Pathogen Interactions; D006801:Humans; D008264:Macrophages / Q000276:immunology / Q000382:microbiology* / Q000502:physiology; D009169:Mycobacterium tuberculosis / Q000276:immunology / Q000472:pathogenicity / Q000502:physiology*; D010588:Phagosomes / Q000276:immunology / Q000382:microbiology* / Q000502:physiology; D015398:Signal Transduction / Q000276:immunology* / Q000502:physiology; D014376:Tuberculosis / Q000276:immunology / Q000382:microbiology*
chemical_list: D001426:Bacterial Proteins