title: Clinical parameters for prediction of successful labor induction after application of intravaginal dinoprostone in nulliparous Chinese women.
abstract: BACKGROUND
  The aim of this study was to compare the possible clinical parameters for prediction of successful labor induction in Chinese nulliparous women.
  
  
  METHODS
  A retrospective, observational trial of labor induction was performed, using a single dose of 10 mg controlled-release dinoprostone for preinduction cervical ripening in 127 nulliparous women (gestational age 38-42 weeks, singleton cephalic presentation). The characteristics of the women with successful labor induction (defined as vaginal delivery achieved on the day of admission; n=80) and failed labor induction (n=47) were compared.
  
  
  RESULTS
  The main differences observed between the groups were gravidity (P<0.05), induction-active labor interval (5.16±2.98 vs. 8.40±3.41; P<0.05) and birth weight (3421.11±368.14 vs. 3566.36±345.16; P<0.05). Logistic regression demonstrated that gravidity (P<0.05) and induction-active labor interval (P<0.05), but not Bishop score, were significant and independent contributing factors for successful labor induction. In the receiver operating characteristic curves for the prediction of successful labor induction, the best cut-off value for gravidity was 3 (95% confidence interval [CI] 0.64-0.83, P=0.000), and the best cut-off value for the induction-active labor interval was 7.96 (95%CI 0.66-0.85, P=0.000).
  
  
  CONCLUSIONS
  Less gravidity and shorter induction-active labor interval predict successful labor induction with reasonable accuracy.
authors: Department of Obstetrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
authors: Lei
authors: L
authors: Hou
authors: Yu
authors: Y
authors: Zhu
authors: Xiaomin
authors: X
authors: Ma
authors: Jianing
authors: J
authors: Li
authors: Weiyuan
authors: W
authors: Zhang
mesh_terms: D000282:Administration, Intravaginal; D000328:Adult; D044466:Asian People; D002681:China; D015232:Dinoprostone / Q000008:administration & dosage* / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007751:Labor, Induced; D016015:Logistic Models; D010298:Parity / Q000187:drug effects*; D011247:Pregnancy; D011379:Prognosis; D012372:ROC Curve; D016896:Treatment Outcome
chemical_list: D015232:Dinoprostone