title: [The concentrations of certain cytokins and lactoferrin in blood and supernatants of cell cultures in patients with autoimmune thyroiditis].
abstract: The analysis was applied to serum and supernatants of day cultures of blood cells of patients with autoimmune thyroiditis and healthy women to determine the content of cytokins (IFN-gamma, TNF-alpha, IL-beta, IL-6, IL-10, L-17) and lactoferrin. The test-system "Cytokin-Stimul-Best" was applied. It is established that in patients with autoimmune thyroiditis the proliferative response of cells to mitogen stimulation is lowered in vitro: the levels of alpha-tumor necrosis factor interleikin-6, lactoferrin. The stimulation index of alpha-tumor necrosis factor, interleikin-6, 1beta, 10 and interferon was statistically reliably lower in supernatants of mitogen stimulated cultures of cells of patients with autoimmune thyroiditis as compared with indicators of healthy women.
authors: R M
authors: RM
authors: Zorina
authors: A V
authors: AV
authors: Ianysheva
authors: T P
authors: TP
authors: Maklakova
authors: T G
authors: TG
authors: Riabicheva
authors: V N
authors: VN
authors: Zorina
mesh_terms: D000328:Adult; D000368:Aged; D018929:Cell Culture Techniques; D002478:Cells, Cultured; D016207:Cytokines / Q000097:blood* / Q000276:immunology; D005260:Female; D006801:Humans; D007781:Lactoferrin / Q000097:blood* / Q000276:immunology; D008875:Middle Aged; D013967:Thyroiditis, Autoimmune / Q000097:blood* / Q000276:immunology
chemical_list: D016207:Cytokines; D007781:Lactoferrin