title: Ethical issues in a stage 1 cognitive-behavioral therapy feasibility study and trial to reduce alcohol use among HIV-infected outpatients in western Kenya.
abstract: Epidemics of both HIV/AIDS and alcohol abuse in sub-Saharan Africa have spurred the conduct of local behavioral therapy trials for these problems, but the ethical issues involved in these trials have not been fully examined. In this paper, we discuss ethical issues that emerged during the conduct of a behavioral intervention adaptation and trial using cognitive-behavioral therapy to reduce alcohol use among HIV-infected outpatients in Eldoret, Kenya. The study was performed within our multinational collaboration, the USAID-Academic Model Providing Access to Healthcare Partnership. We discuss relevant ethical considerations and how we addressed them.
authors: Brown University School of Medicine, Providence, RI, USA. Rebecca_Papas@brown.edu
authors: Rebecca K
authors: RK
authors: Papas
authors: Benson N
authors: BN
authors: Gakinya
authors: Joyce B
authors: JB
authors: Baliddawa
authors: Steve
authors: S
authors: Martino
authors: Kendall J
authors: KJ
authors: Bryant
authors: Eric M
authors: EM
authors: Meslin
authors: John E
authors: JE
authors: Sidle
mesh_terms: D000428:Alcohol Drinking / Q000453:epidemiology / Q000517:prevention & control*; D000437:Alcoholism / Q000150:complications / Q000453:epidemiology / Q000628:therapy*; D035843:Biomedical Research / Q000941:ethics*; D017321:Clinical Trials, Phase I as Topic / Q000941:ethics*; D015928:Cognitive Behavioral Therapy; D058872:Epidemics; D032984:Ethics, Research; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology / Q000628:therapy*; D006801:Humans; D007391:International Cooperation; D007630:Kenya; D008297:Male; D010045:Outpatients