title: Diagnostic accuracy of nocturnal oximetry for detection of sleep apnea syndrome in stroke rehabilitation.
abstract: OBJECTIVE
  Sleep apnea syndrome (SAS) is a common sleep disorder in stroke patients and is associated with decreased recovery and increased risk of recurrent stroke and mortality. The standard diagnostic test for SAS is poly(somno)graphy, but this is often not feasible in stroke rehabilitation settings. This study investigated the diagnostic value of nocturnal oximetry for screening SAS in stroke rehabilitation.
  
  
  METHODS
  Fifty-six stroke patients underwent nocturnal polygraphy and oximetry. Sensitivity, specificity, and positive and negative predictive values for the oxygen desaturation index were calculated. Patient and sleep characteristics were used to develop a predictive model of apnea-hypopnea index.
  
  
  RESULTS
  Forty-six percent of the stroke patients had SAS. The majority of SAS patients was male, older, and had a higher body mass index than patients without SAS. Sensitivity, specificity, and positive and negative predictive values for the oxygen desaturation index ≥15 were, respectively, 77%, 100%, 100%, and 83%. Oxygen desaturation index predicted 87% of the variance in the apnea-hypopnea index. Patient characteristics did not add significantly to the prediction model.
  
  
  CONCLUSIONS
  Nocturnal oximetry is an accurate diagnostic screening instrument for the detection of SAS in stroke patients.
authors: Heliomare, Postbus 78, 1940 AB Beverwijk, the Netherlands. j.aaronson@heliomare.nl
authors: Justine A
authors: JA
authors: Aaronson
authors: Tijs
authors: T
authors: van Bezeij
authors: Joost G
authors: JG
authors: van den Aardweg
authors: Coen A M
authors: CA
authors: van Bennekom
authors: Winni F
authors: WF
authors: Hofman
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D015992:Body Mass Index; D002545:Brain Ischemia / Q000150:complications / Q000628:therapy; D002543:Cerebral Hemorrhage / Q000150:complications / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010092:Oximetry / Q000379:methods*; D010100:Oxygen / Q000097:blood; D017286:Polysomnography; D011237:Predictive Value of Tests; D012372:ROC Curve; D012044:Regression Analysis; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012737:Sex Factors; D012891:Sleep Apnea Syndromes / Q000175:diagnosis*; D000071939:Stroke Rehabilitation
chemical_list: D010100:Oxygen