title: Regulation of intestinal morphology and GALT by pituitary hormones in the rat.
abstract: Here, the effects of neurointermediate (NIL), anterior (AL), and total hypophysectomy (HYPOX) on ileal mucosa cells and gut-associated lymphoid tissue (GALT) are reported. Compared with the sham-operated (SHAM) rats, the villi height and goblet cells numbers were significantly decreased in all groups. Lamina propria area decreased in AL and HYPOX, but not in NIL animals. CD8(+)  but not CD4(+)  lymphocytes decreased in the HYPOX and NIL groups. Paneth cells did not change, while IgA cells, IgM cells, and secretory IgA were significantly decreased in all groups. NIL but not AL animals lost significant numbers of IgA cells and secretory IgA. In summary, pituitary hormones exert lobe-specific regulatory effects on the gut and on GALT.
authors: Departamento de Morfología, Laboratorio de Morfología Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, IPN, México.
authors: Luz María
authors: LM
authors: Cárdenas-Jaramillo
authors: Andrés
authors: A
authors: Quintanar-Stephano
authors: Rosa Adriana
authors: RA
authors: Jarillo-Luna
authors: Víctor
authors: V
authors: Rivera-Aguilar
authors: Gabriela
authors: G
authors: Oliver-Aguillón
authors: Rafael
authors: R
authors: Campos-Rodríguez
authors: Kalman
authors: K
authors: Kovacs
authors: Istvan
authors: I
authors: Berczi
mesh_terms: D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000378:metabolism; D018414:CD8-Positive T-Lymphocytes / Q000378:metabolism; D020397:Goblet Cells / Q000276:immunology / Q000378:metabolism; D013006:Growth Hormone / Q000276:immunology / Q000378:metabolism; D007016:Hypophysectomy; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism; D007070:Immunoglobulin A / Q000276:immunology / Q000378:metabolism; D007075:Immunoglobulin M / Q000276:immunology / Q000378:metabolism; D007413:Intestinal Mucosa / Q000276:immunology* / Q000378:metabolism; D007421:Intestine, Small / Q000276:immunology* / Q000378:metabolism; D008221:Lymphoid Tissue / Q000276:immunology* / Q000378:metabolism; D008297:Male; D019879:Paneth Cells / Q000378:metabolism; D010903:Pituitary Gland, Anterior / Q000378:metabolism* / Q000601:surgery; D052716:Pituitary Gland, Intermediate / Q000378:metabolism* / Q000601:surgery; D010904:Pituitary Gland, Posterior / Q000378:metabolism / Q000601:surgery; D010907:Pituitary Hormones / Q000276:immunology / Q000378:metabolism*; D010913:Pituitary-Adrenal System / Q000378:metabolism; D011388:Prolactin / Q000276:immunology / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D014667:Vasopressins / Q000276:immunology / Q000378:metabolism
chemical_list: D007070:Immunoglobulin A; D007075:Immunoglobulin M; D010907:Pituitary Hormones; D014667:Vasopressins; D011388:Prolactin; D013006:Growth Hormone