title: Radioiodine treatment in McCune-Albright syndrome with hyperthyroidism.
abstract: McCune-Albright syndrome (MAS) is a sporadic disease characterized by polyostotic fibrous dysplasia, "café-au-lait" spots and hyperfunctional endocrinopathies. Pathophysiological basis is activating mutation of the gene that encodes the alpha subunit of Gs membrane protein that stimulates the intracellular production of cAMP, conferring autonomous secretion of the gland in particular. One of the uncommon endocrine manifestations is hyperthyroidism. We present a patient who had café-au-lait spots, polyostotic fibrous dysplasia and hyperthyroidism. She was treated with radioactive iodine for the symptoms of hyperthyroidism and subsequently relieved from hyperthyroid features.
authors: Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors: Dhritiman
authors: D
authors: Chakraborty
authors: Bhagwant Rai
authors: BR
authors: Mittal
authors: Raghava
authors: R
authors: Kashyap
authors: Kuruva
authors: K
authors: Manohar
authors: Anish
authors: A
authors: Bhattacharya
authors: Anil
authors: A
authors: Bhansali