title: Convergent syntheses of 3,6-dihydroxydec-4-enolides.
abstract: The total syntheses of the 3,6-dihydroxydecanolide from Cordyceps militaris and the novel C-3 epimer are reported using a diastereoselective Nozaki-Hiyama-Kishi reaction in the key cyclization to generate the 6R stereocenter.
authors: School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK.
authors: Jonathan C
authors: JC
authors: Killen
authors: Lorraine C
authors: LC
authors: Axford
authors: Sarah E
authors: SE
authors: Newberry
authors: Thomas J
authors: TJ
authors: Simpson
authors: Christine L
authors: CL
authors: Willis
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D032661:Cordyceps / Q000737:chemistry*; D003500:Cyclization; D007783:Lactones / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: C576447:3,6-dihydroxydecanolide; D001688:Biological Products; D007783:Lactones