title: Unexpected outcome after sclerotherapy of simple renal cyst.
abstract: BACKGROUND
  Simple renal cysts usually have benign clinical features. We report a rare case of papillary renal cell carcinoma (RCC) associated with a large recurrent simple cyst following sclerotherapy.
  
  
  METHODS
  A 47-year-old Japanese woman received minocycline sclerotherapy for a large (9 cm in diameter) simple left renal cyst in May 2005. The cyst regrew, and second-line sclerotherapy with ethanol was performed in November 2005. Three years later, she developed papillary RCC on the wall of the recurrent renal cyst. Radical nephrectomy was performed, but the patient died of metastatic disease 15 months after surgery.
  
  
  CONCLUSIONS
  Malignant transformation from recurrent simple renal cyst to RCC may occur in the years following sclerotherapy, underscoring the need for long-term follow-up.
authors: Oyokyo Kidney Research Institute, Hirosaki Hospital, 90 Yamazaki Kozawa, Hirosaki, Aomori 036-8243, Japan. bikkuri@opal.plala.or.jp
authors: Yasuhiro
authors: Y
authors: Hashimoto
authors: Atsushi
authors: A
authors: Imai
authors: Noriko
authors: N
authors: Tokui
authors: Atsushi
authors: A
authors: Sasaki
authors: Hisao
authors: H
authors: Saitoh
authors: Takuya
authors: T
authors: Koie
authors: Chikara
authors: C
authors: Ohyama
mesh_terms: D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000209:etiology*; D008875:Middle Aged; D012597:Sclerosing Solutions / Q000009:adverse effects*; D015911:Sclerotherapy / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D012597:Sclerosing Solutions