title: Culture systems: air quality.
abstract: Poor laboratory air quality is a known hazard to the culture of human gametes and embryos. Embryologists and chemists have employed analytical methods for identifying and measuring bulk and select air pollutants to assess the risk they pose to the embryo culture system. However, contaminant concentrations that result in gamete or embryotoxicity are poorly defined. Combating the ill effects of poor air quality requires an understanding of how toxicants can infiltrate the laboratory, the incubator, and ultimately the culture media. A further understanding of site-specific air quality can then lead to the consideration of laboratory design and management strategies that can minimize the deleterious effects that air contamination may have on early embryonic development in vitro.
authors: Reproductive Technology Laboratory, Martha Jefferson Hospital, Charlottesville, VA, USA. Ted.thomas@mjh.org
authors: Theodore
authors: T
authors: Thomas
mesh_terms: D016902:Air Pollution, Indoor / Q000032:analysis*; D003470:Culture Media / Q000737:chemistry; D046149:Embryo Culture Techniques / Q000295:instrumentation / Q000379:methods*; D004780:Environment, Controlled; D005307:Fertilization in Vitro; D006801:Humans; D007185:Incubators; D007753:Laboratories; D052638:Particulate Matter / Q000032:analysis; D011312:Pressure; D014466:Ultraviolet Rays; D055549:Volatile Organic Compounds / Q000032:analysis
chemical_list: D003470:Culture Media; D052638:Particulate Matter; D055549:Volatile Organic Compounds