title: Iodine-125 seed implantation in the treatment of sacrococcygeal chordoma: a case report.
abstract: The objective of this was to summarize the efficacy and safety of iodine-125 seed implantation in the treatment of sacrococcygeal chordoma. CT-guided implantation of radioactive iodine-125 seed was applied in treating a patient with sacrococcygeal chordoma. The incidence of complications was recorded and the results were evaluated and analyzed, to compare the postoperative complications and recurrence rate of sacrococcygeal chordoma. The patient was followed up to 15 months after operation. The minimum peripheral dose was 180 Gy, and 8 months after the implantation, the tumor mass was reduced significantly. There was no serious complications detected during the follow-up period. Radioactive iodine-125 seed implantation can improve the target volume dose, with the high doses of radioactive iodine-125 seed, the tumor, which was refractory and insensitive to chemotherapy and radiotherapy, can be effectively controlled and complications are less than surgical treatment. However, the long-term efficacy of this treatment needs further follow-up.
authors: Cancer Center, Institute of Surgical Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China.
authors: Rong-hui
authors: RH
authors: Ni
authors: Ge
authors: G
authors: Wang
authors: Zhi-min
authors: ZM
authors: Zhang
authors: Jun-gang
authors: JG
authors: Ma
mesh_terms: D000368:Aged; D002817:Chordoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D012445:Sacrococcygeal Region / Q000000981:diagnostic imaging / Q000473:pathology / Q000528:radiation effects* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D007457:Iodine Radioisotopes