title: Sutures coated with antiseptic pomade to prevent bacterial colonization: a randomized clinical trial.
abstract: OBJECTIVE
  The aim of this study was to assess if an antiseptic pomade could reduce the bacterial colonization on multifilament sutures.
  
  
  METHODS
  A randomized clinical trial was conducted with 40 volunteer patients of both sexes aged 18-70, randomly separated into experimental (n = 20) and control (n = 20) groups. The experimental group received pomade-coated sutures (iodoform + calendula) and the control group uncoated sutures. Two millimeters of the suture was harvested from each patient from the 1st to the 15th postoperative day. The bacteria that had adhered to them were cultured. The number of colony-forming units per milliliter (CFU/mL) was determined and the groups were compared using the Mann-Whitney statistical test (P < .05).
  
  
  RESULTS
  The experimental group showed a significant reduction in bacterial growth compared with the control group (P = .002).
  
  
  CONCLUSIONS
  In this experimental model, the antiseptic pomade was effective in reducing bacterial colonization on silk braided sutures.
authors: Clinical Center of Research in Stomatology, Juiz de Fora, Brazil.
authors: Fernando
authors: F
authors: Cruz
authors: Fabiola
authors: F
authors: Leite
authors: Gustavo
authors: G
authors: Cruz
authors: Silvia
authors: S
authors: Cruz
authors: Juarez
authors: J
authors: Reis
authors: Matthew
authors: M
authors: Pierce
authors: Mauro
authors: M
authors: Cruz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects / Q000254:growth & development; D058491:Bacterial Load / Q000187:drug effects; D001431:Bacteriological Techniques; D020838:Calendula; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006847:Hydrocarbons, Iodinated / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D019647:Oral Surgical Procedures; D008517:Phytotherapy / Q000379:methods; D010938:Plant Oils / Q000008:administration & dosage / Q000627:therapeutic use; D047011:Silk; D016037:Single-Blind Method; D013530:Surgical Wound Infection / Q000517:prevention & control*; D013537:Sutures / Q000382:microbiology*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000891:Anti-Infective Agents, Local; D006847:Hydrocarbons, Iodinated; D010938:Plant Oils; D047011:Silk; C010473:iodoform