title: Can an athlete have too much ticker? Hypertrophic cardiomyopathy in young athletes.
abstract: Sudden cardiac death (SCD) is an uncommon but devastating potential consequence of participation in competitive sport. It is seen in adolescent and young adult athletes. The most common cause of this, hypertrophic cardiomyopathy (HCM), is a genetic disorder responsible for more than a third of cases and is manageable. Screening is undertaken for HCM, using differing strategies in Europe and North America. Screening and early diagnosis have reduced the mortality rate but has come at a significant economic cost. The evidence and relevant arguments for and against screening are presented together with management strategies as reflected by an illustrative case.
authors: University of New South Wales Medical School, Sydney, New South Wales, Australia.
authors: Nicholas M
authors: NM
authors: Fitzgerald
authors: Megan
authors: M
authors: Sherwood
authors: Dominic A
authors: DA
authors: Fitzgerald
mesh_terms: D000293:Adolescent; D056352:Athletes; D024741:Cardiomyopathy, Hypertrophic, Familial / Q000150:complications / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D002317:Cardiovascular Agents / Q000627:therapeutic use; D016757:Death, Sudden, Cardiac / Q000209:etiology* / Q000517:prevention & control; D005820:Genetic Testing; D016027:Heart Transplantation; D006801:Humans; D008403:Mass Screening; D018570:Risk Assessment; D012307:Risk Factors; D055815:Young Adult
chemical_list: D002317:Cardiovascular Agents