title: The use of web ontology languages and other semantic web tools in drug discovery.
abstract: BACKGROUND
  To optimize drug development processes, pharmaceutical companies require principled approaches to integrate disparate data on a unified infrastructure, such as the web. The semantic web, developed on the web technology, provides a common, open framework capable of harmonizing diversified resources to enable networked and collaborative drug discovery.
  
  
  METHODS
  We survey the state of art of utilizing web ontologies and other semantic web technologies to interlink both data and people to support integrated drug discovery across domains and multiple disciplines. Particularly, the survey covers three major application categories including: i) semantic integration and open data linking; ii) semantic web service and scientific collaboration and iii) semantic data mining and integrative network analysis.
  
  
  RESULTS
  The reader will gain: i) basic knowledge of the semantic web technologies; ii) an overview of the web ontology landscape for drug discovery and iii) a basic understanding of the values and benefits of utilizing the web ontologies in drug discovery.
  
  
  CONCLUSIONS
  i) The semantic web enables a network effect for linking open data for integrated drug discovery; ii) The semantic web service technology can support instant ad hoc collaboration to improve pipeline productivity and iii) The semantic web encourages publishing data in a semantic way such as resource description framework attributes and thus helps move away from a reliance on pure textual content analysis toward more efficient semantic data mining.
authors: Zhejiang University, School of Computer Science, Hangzhou Zhejiang 310027, China  +86 571 87953703 ;  +86 571 87953079 ;  huajunsir@gmail.com.
authors: Huajun
authors: H
authors: Chen
authors: Guotong
authors: G
authors: Xie