title: Peptoid transporters: effects of cationic, amphipathic structure on their cellular uptake.
abstract: Two cationic, amphipathic peptoids (poly-N-substituted glycines) were developed as new molecular transporters, which have extensive cellullar uptake and utilize different internalization mechanisms from purely cationic polyguanidine comparators.
authors: Bioengineering, Stanford University, Palo Alto, CA 94305, USA.
authors: Wei
authors: W
authors: Huang
authors: Jiwon
authors: J
authors: Seo
authors: Jennifer S
authors: JS
authors: Lin
authors: Annelise E
authors: AE
authors: Barron
mesh_terms: D001692:Biological Transport; D002352:Carrier Proteins / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D002412:Cations; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D057846:Cell-Penetrating Peptides / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D015195:Drug Design; D004705:Endocytosis; D005260:Female; D005452:Fluoresceins; D005456:Fluorescent Dyes; D006146:Guanidines / Q000494:pharmacology; D006801:Humans; D034442:N-substituted Glycines / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D002352:Carrier Proteins; D002412:Cations; D057846:Cell-Penetrating Peptides; D005452:Fluoresceins; D005456:Fluorescent Dyes; D006146:Guanidines; D034442:N-substituted Glycines; C024098:6-carboxyfluorescein