title: Sonochemical coatings of ZnO and CuO nanoparticles inhibit Streptococcus mutans biofilm formation on teeth model.
abstract: Antibiotic resistance has prompted the search for new agents that can inhibit bacterial growth. We recently reported on the antibiofilm activities of nanosized ZnO and CuO nanoparticles (NPs) synthesized by using sonochemical irradiation. In this study, we examined the antibacterial activity of ZnO and CuO NPs in a powder form and also examined the antibiofilm behavior of teeth surfaces that were coated with ZnO and CuO NPs using sonochemistry. Free ZnO and CuO NPs inhibited biofilm formation of  Streptococcus mutans . Furthermore, by using the sonochemical procedure, we were able to coat teeth surfaces that inhibited bacterial colonization.
authors: Kanbar Laboratory for Nanomaterials, Department of Chemistry, The Bar-Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan, Israel.
authors: Michal
authors: M
authors: Eshed
authors: Jonathan
authors: J
authors: Lellouche
authors: Shlomo
authors: S
authors: Matalon
authors: Aharon
authors: A
authors: Gedanken
authors: Ehud
authors: E
authors: Banin
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology; D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development; D040761:Biomimetic Materials / Q000737:chemistry; D003300:Copper / Q000737:chemistry / Q000494:pharmacology*; D017886:Durapatite / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry*; D013295:Streptococcus mutans / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D013499:Surface Properties; D014070:Tooth / Q000382:microbiology*; D014465:Ultrasonics; D015034:Zinc Oxide / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000890:Anti-Infective Agents; D003300:Copper; D017886:Durapatite; D015034:Zinc Oxide; C030973:cupric oxide