title: Characterization of oral double balloon endoscopy in the dog.
abstract: Exploration of the canine small intestine using conventional endoscopy is restricted to the duodenum and/or the ileum. Double balloon endoscopy (DBE) is a 'push and pull' technique that has been described in humans and permits a complete exploration of the small intestine. In this study, oral DBE was performed on 12 healthy dogs (10-34kg) to characterize for the first time the efficiency, exploration dynamics and safety of the technique. DBE was successful in 83% of dogs; the average estimated insertion depth of the endoscope was 287±36cm, and the average duration of the exploration was 84±8min. No complications or relevant adverse clinical effects were observed, and there was no indication of post-procedure pancreatitis based on serology of two specific markers of pancreatitis (amylase and lipase) and the immediate nonspecific inflammatory mediator C-reactive protein. The study showed that oral DBE is viable and safe in the dog, allowing for the diagnosis and treatment of gastrointestinal diseases deep in the small intestine to an extent that has not previously been possible using conventional endoscopy.
authors: Department of Anatomy and Comparative Pathology, Veterinary Faculty, University of Murcia, Spain.
authors: R
authors: R
authors: Sarria
authors: O
authors: O
authors: López Albors
authors: F
authors: F
authors: Soria
authors: I
authors: I
authors: Ayala
authors: E
authors: E
authors: Pérez Cuadrado
authors: P
authors: P
authors: Esteban
authors: R
authors: R
authors: Latorre
mesh_terms: D000681:Amylases / Q000097:blood; D000818:Animals; D015415:Biomarkers; D002097:C-Reactive Protein / Q000378:metabolism; D004285:Dogs / Q000033:anatomy & histology*; D058582:Double-Balloon Enteroscopy / Q000662:veterinary*; D005260:Female; D008049:Lipase / Q000097:blood; D008297:Male
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein; D008049:Lipase; D000681:Amylases