title: Modified Roux-en-Y gastric bypass for type 2 diabetes mellitus in China.
abstract: OBJECTIVE
  This study aimed to evaluate the efficacy of modified Roux-en-Y gastric bypass for type 2 diabetes mellitus.
  
  
  METHODS
  Forty-five type 2 diabetes mellitus patients underwent modified Roux-en-Y gastric bypass at WeiFang People's Hospital. Data on patient demographics, fasting plasma glucose (FPG), body mass index (BMI), medication use, remission and hemoglobin A1c (HbAlc) were prospectively collected and analyzed.
  
  
  RESULTS
  At 6 months after surgery, all of these 45 patients obtained remission or a marked improvement. FPG was in the normal range in 39 (86.7%) patients stopping medicine treatment for their diabetes. Six patients (13.3%) had an obvious reduced abnormal FPG and they only required lower drug dosage. No statistically significant differences were found between the obese or non-obese groups (p=0.311). The mean BMI dropped from 28.9±3.0 kg/m2 to 27.4±2.8 kg/m2 (p=0.000) at the third month and 26.3±2.5 kg/m2 (p=0.000) at the sixth month. HbAlc decreased from their preoperative values of 7.4%±2.2% to 6.3%±1.5% (p=0.000) at the third month and 5.1%±0.9% (p=0.000) at the sixth month.
  
  
  CONCLUSIONS
  Modified Roux-en-Y gastric bypass was effective in treating type 2 diabetes mellitus, independent of body mass index.
authors: Department of General Surgery, WeiFang People's Hospital, WeiFang, ShanDong, China.
authors: Zuo-Cheng
authors: ZC
authors: Sun
authors: Wen-Sheng
authors: WS
authors: Yu
authors: Ying
authors: Y
authors: Na
authors: Dong-Mei
authors: DM
authors: Xu
authors: Fu-Chang
authors: FC
authors: Zheng
authors: Jia-You
authors: JY
authors: Xu
authors: Chong-Bing
authors: CB
authors: Sun
authors: Hui-Min
authors: HM
authors: Xu
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D002681:China; D003924:Diabetes Mellitus, Type 2 / Q000601:surgery*; D005260:Female; D015390:Gastric Bypass / Q000379:methods*; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human