title: Comparison of the antibacterial effect of modified 3-mix paste versus Ultrapex over anaerobic microorganisms from infected root canals of primary teeth: an in vitro study.
abstract: OBJECTIVE
  The aim of this study was to evaluate in vitro the antimicrobial efficacy of a modified 3-mix paste and to compare it with an iodoform paste (Ultrapex) against anaerobic microorganisms isolated from root canals of infected or necrotic primary teeth.
  
  
  METHODS
  An in vitro experimental assay was performed over isolated and identified anaerobic microorganisms of 21 samples, in order to compare the antimicrobial ability of both root canal filling materials, using a disc-diffusion method.
  
  
  RESULTS
  A total of 21 microbial samples (15 polymicrobial and 6 monomicrobial) were obtained, from which 19 different strains were identified. Modified 3-mix paste showed an excellent antimicrobial effect against most of both kinds of microbial samples, although some of them exhibited resistance; on the other hand, Ultrapex showed only minimal antimicrobial ability (null or low categories). Clostridium ramosum exhibited the most resistance to both materials.
  
  
  CONCLUSIONS
  The bactericidal effect of the modified 3-mix paste was superior to Ultrapex, with a statistically significant difference, against anaerobic microorganisms isolated from infected root canals of primary teeth.
authors: Pediatric Dentistry Posgraduate Program, Facultad de Estomatología, Universidad Autónoma de San Luis Potosí, México.
authors: N
authors: N
authors: Velasco-Loera
authors: Y
authors: Y
authors: De Alba-Vazquez
authors: A
authors: A
authors: Garrocho-Rangel
authors: A M
authors: AM
authors: Gonzalez-Amaro
authors: H
authors: H
authors: Flores-Reyes
authors: A J
authors: AJ
authors: Pozos-Guillen
mesh_terms: D000190:Actinomyces / Q000187:drug effects; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D001424:Bacterial Infections / Q000382:microbiology; D001439:Bacteroides / Q000187:drug effects; D001644:Bifidobacterium / Q000187:drug effects; D002126:Calcium Hydroxide / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects; D002939:Ciprofloxacin / Q000494:pharmacology; D003013:Clostridium / Q000187:drug effects; D003786:Dental Pulp Cavity / Q000382:microbiology*; D003788:Dental Pulp Diseases / Q000382:microbiology; D003790:Dental Pulp Necrosis / Q000382:microbiology; D004338:Drug Combinations; D024881:Drug Resistance, Bacterial; D058834:Gemella / Q000187:drug effects; D006801:Humans; D008422:Materials Testing; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008911:Minocycline / Q000494:pharmacology; D001443:Prevotella melaninogenica / Q000187:drug effects; D011425:Propionibacterium acnes / Q000187:drug effects; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D012828:Silicones / Q000494:pharmacology*; D034367:Streptococcus intermedius / Q000187:drug effects; D014094:Tooth, Deciduous / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D012387:Root Canal Filling Materials; D012828:Silicones; C029584:calcium hydroxide, iodoform, silicone oil drug combination; D008795:Metronidazole; D002939:Ciprofloxacin; D008911:Minocycline; D002126:Calcium Hydroxide