title: Discrimination of colon cancer stem cells using noncanonical amino acid.
abstract: Cancer stem cells (CSCs) may be responsible for tumor recurrence. Metabolic labelling of newly synthesized proteins with non-canonical amino acids allows us to discriminate CSCs in mixed populations due to the quiescent nature of these cells.
authors: Department of Chemistry and Biochemistry & Nanocenter, University of South Carolina, Columbia, SC 29208, USA.
authors: Xinrui
authors: X
authors: Duan
authors: Honglin
authors: H
authors: Li
authors: Hexin
authors: H
authors: Chen
authors: Qian
authors: Q
authors: Wang
mesh_terms: D000480:Alkynes / Q000378:metabolism*; D002469:Cell Separation / Q000379:methods*; D003110:Colonic Neoplasms / Q000473:pathology*; D005998:Glycine / Q000031:analogs & derivatives* / Q000378:metabolism; D045325:HCT116 Cells; D006801:Humans; D014411:Neoplastic Stem Cells / Q000378:metabolism / Q000473:pathology*
chemical_list: D000480:Alkynes; C551041:homopropargylglycine; D005998:Glycine