title: Oxidative coupling of indoles with ethyl 2-(disubstituted amino)acetates: an approach to achieve indolylglycine derivatives.
abstract: An efficient method for the synthesis of indolylglycine derivatives is described. The oxidative coupling reactions of ethyl 2-(disubstituted amino)acetates with indoles proceeded smoothly in the presence of meta-chloroperoxybenzoic acid (mCPBA) under ambient conditions to produce indolylglycine derivatives in satisfactory to excellent yields.
authors: State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116023, China.
authors: Zhanwei
authors: Z
authors: Xu
authors: Xiaoqiang
authors: X
authors: Yu
authors: Xiujuan
authors: X
authors: Feng
authors: Ming
authors: M
authors: Bao
mesh_terms: D000625:Aminooxyacetic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D002384:Catalysis; D002723:Chlorobenzoates / Q000737:chemistry*; D005998:Glycine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D058451:Oxidative Coupling
chemical_list: D002723:Chlorobenzoates; D007211:Indoles; D000625:Aminooxyacetic Acid; C000433:3-chloroperbenzoic acid; D005998:Glycine