title: [Endogenous sex hormone testosterone and haemostatic factors in young  men after myocardial infarction].
abstract: OBJECTIVE
  To compare levels of haemostatic factors and sex hormones in young men after myocardial infarction, to study relationship between sex hormones and factors of hemostasis.
  
  
  METHODS
  We studied 32 men aged 30-50 years with diagnosis of myocardial infarction. Patients were divided into 2 groups according to age: group 1 - 11 patients aged 30-39 years, group 2 - 21 patients aged of 40-50 years. Levels of sex hormones were measured by IFA. Level of fibrinogen, prothrombin index, plasma recalcification time, fibrinolytic activity, indices of aggregation and disaggregation were also determined.
  
  
  RESULTS
  Testosterone level in the group I was more decreased in comparison with the Group 2 and level of fibrinogen was higher in the group 1 (3.9+/-0,7) in comparison with the group II (3.1+/-0.8; p<0.05). Pearsons correlation between estradiol and fibrinogen in the group 1 was 0.613 (p<0.05). No such relationship was found in the group 2. Pearsons correlation between testosterone and prothrombin index was 0,477 (p<0.009).
  
  
  CONCLUSIONS
  Endogenous testosterone level is one of the factors which influence haemostatic system, but this effect is not well-defined and requires further study.
authors: K N
authors: KN
authors: Kerimova
authors: A B
authors: AB
authors: Bakhshaliev
authors: R F
authors: RF
authors: Gadzhiev
authors: É S
authors: ÉS
authors: Gamidova
mesh_terms: D000328:Adult; D000367:Age Factors; D001779:Blood Coagulation Factors; D001780:Blood Coagulation Tests / Q000379:methods; D004958:Estradiol / Q000097:blood; D005340:Fibrinogen; D006487:Hemostasis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000453:epidemiology; D010974:Platelet Aggregation; D012307:Risk Factors; D012737:Sex Factors; D013223:Statistics as Topic; D013739:Testosterone / Q000097:blood*
chemical_list: D001779:Blood Coagulation Factors; D013739:Testosterone; D004958:Estradiol; D005340:Fibrinogen