title: Anti-irritants agents for the treatment of irritant contact dermatitis: clinical and patent perspective.
abstract: This overview defines whether anti-irritant agents, in fact, inhibit, prevent or treat irritant contact dermatitis (ICD) in man. We performed a literature search using PubMed, EMBASE, and Scopus via the library at University of California San Francisco, and a hand search of relevant text books to investigate chemicals that can be considered anti-irritants in either prevention or treatment. Emphasis was placed on data that included quantitative and qualitative results and that followed evidence-based dermatological guidelines. Related patents were summarized. Conflicting observations summarized here suggest well controlled, but often arduous, field type studies are required for confirmation.
authors: Department of Dermatology, University of California, School of Medicine, Box 0989, Surge 110, 90 Medical Center Way, San Francisco, CA 94143-0989, USA.
authors: Hongbo
authors: H
authors: Zhai
authors: Howard I
authors: HI
authors: Maibach
mesh_terms: D017453:Dermatitis, Irritant / Q000188:drug therapy* / Q000473:pathology / Q000517:prevention & control; D003879:Dermatologic Agents / Q000494:pharmacology*; D019317:Evidence-Based Medicine; D006801:Humans; D007509:Irritants / Q000009:adverse effects; D010330:Patents as Topic; D017410:Practice Guidelines as Topic
chemical_list: D003879:Dermatologic Agents; D007509:Irritants