title: [The monitoring of application of dabigatran as a remedy of prevention of thromboembolic complications after hip joint arthroplasty].
abstract: The analysis was applied to the indicators of hemostasis system under application of new anticoagulant, dabigatran etexilat, after hip joint arthroplasty. It is established that among the coagulation methods analysis the most specific to the effect of dabigatran is the testing of thrombin and echitox time of coagulation. Considering low sensitivity of the echitox to anticoagulation effect of D-dimer the echitox test is optimal for laboratory monitoring of application of dabigatran after orthopedic intervention.
authors: A P
authors: AP
authors: Momot
authors: E V
authors: EV
authors: Grigor'ev
authors: L P
authors: LP
authors: Tsyvkina
authors: M Iu
authors: MIu
authors: Panov
authors: I V
authors: IV
authors: Merkulov
mesh_terms: D019644:Arthroplasty, Replacement, Hip; D001562:Benzimidazoles / Q000008:administration & dosage*; D000069604:Dabigatran; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods*; D013923:Thromboembolism / Q000097:blood* / Q000517:prevention & control*; D014914:Whole Blood Coagulation Time; D015091:beta-Alanine / Q000008:administration & dosage / Q000031:analogs & derivatives*
chemical_list: D001562:Benzimidazoles; D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; D015091:beta-Alanine; D000069604:Dabigatran