title: Congenital anomalies and childhood celiac disease in Sweden.
abstract: Previously, chromosomal anomalies and, to a lesser extent, other congenital anomalies have been associated with an increased risk of celiac disease (CD). We investigated these associations using a systematic approach. We identified all of the singleton children (792,401) born in Sweden between 1987 and 1993, and obtained cases of CD using the Swedish National Inpatient Registry. We applied Cox regression models as well as sibling designs to study the association between congenital anomalies and childhood CD. We observed that anomalies of face, neck, ear, heart, digestive tract, or chromosomes were associated with CD.
authors: Department of Clinical Sciences, Unit for Social Epidemiology, Lund University, Malmo, Sweden. carl_johan.wingren@med.lu.se
authors: Carl Johan
authors: CJ
authors: Wingren
authors: Daniel
authors: D
authors: Agardh
authors: Juan
authors: J
authors: Merlo
mesh_terms: D000293:Adolescent; D000328:Adult; D002446:Celiac Disease / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D002869:Chromosome Aberrations; D000013:Congenital Abnormalities; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D016016:Proportional Hazards Models; D012042:Registries; D012307:Risk Factors; D035781:Siblings; D013548:Sweden; D055815:Young Adult