title: Wernicke's Encephalopthy Associated with Hyperemesis Gravidarum - A Case Report.
abstract: Two cases of Wernicke's encephalopathy due to hyperemesis gravidarum are described. The first patient presented with bilateral papilloedema, altered sensorium and the second with bilateral retinal haemorrhages, ophthalmoplegia and nystagmus. Both patients were diagnosed with Wernicke's encephalopathy on clinical ground since there were no laboratory facilities to measure red cell transketolase and thiamine pyrophosphate levels. This is a rare but treatable complication of hyperemesis gravidarum (HG) and due to lack of diagnostic tools, there is often diagnostic uncertainty, delay in commencing appropriate treatment, as well as irreversible damage to the upper brain stem and death.
authors: Department of Medicine, Hospital Kota Bharu, 15586 Kota Bharu, Kelantan, Malaysia.
authors: Wahinuddin
authors: W
authors: Sulaiman
authors: Azerin
authors: A
authors: Othman
authors: Monniaty
authors: M
authors: Mohamad
authors: Hj Rosemi
authors: HR
authors: Salleh
authors: Lily
authors: L
authors: Mushahar