title: Optimal cut-off levels of body mass index and waist circumference in relation to each component of metabolic syndrome (MetS) and the number of MetS component.
abstract: OBJECTIVE
  There is an ethnic difference of obesity index to diagnose metabolic syndrome. The authors explored the optimal cut-off levels for body mass index (BMI) and waist circumference (WC) in relation to each component of metabolic syndrome.
  
  
  METHODS
  Receiver operating characteristics (ROC) analysis was used to determine the optimal cut-off levels for each component of metabolic syndrome. This study included 4572 workers aged 42.5±9.9 years.
  
  
  RESULTS
  The optimal BMI cut-off values for diabetes mellitus, hypertension or dyslipidemia varied from 23.0 to 24.3 kg/m(2). As for WC, the optimal cut-off values varied from 83.0 to 83.7 cm. The optimal BMI cut-off values relating with one to three components of metabolic syndrome varied from 23.2 to 25.3 kg/m(2). As for WC, the optimal cut-off values varied from 83.0 to 85.0 cm. Pair-wise comparison of ROC curves showed that WC has an advantage in relation to metabolic syndrome and its components compared with BMI. By logistic regression analysis, odds ratios of obesity indices for hypertension, dyslipidemia or the number of metabolic component were all significantly increased. As for diabetes mellitus, odds ratios of BMI ≥25 and WC ≥85 significantly increased, respectively.
  
  
  CONCLUSIONS
  Japanese criteria of obesity in metabolic syndrome in man may be appropriate for diabetes mellitus. Ethnic difference in criteria of obesity in Asian metabolic syndrome exists, and mutual comparisons in the prevalence of metabolic syndrome have a difficulty to conduct.
authors: Department of Hygiene and Public Health, Nippon Medical School, 1-1-5 Sendagi, Tokyo 113-8602, Japan. kawada@nms.ac.jp
authors: Tomoyuki
authors: T
authors: Kawada
authors: Toshiaki
authors: T
authors: Otsuka
authors: Hirofumi
authors: H
authors: Inagaki
authors: Yoko
authors: Y
authors: Wakayama
authors: Qing
authors: Q
authors: Li
authors: Ying Ji
authors: YJ
authors: Li
authors: Masao
authors: M
authors: Katsumata
mesh_terms: D000328:Adult; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000208:ethnology / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000208:ethnology / Q000378:metabolism; D007564:Japan / Q000208:ethnology; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis* / Q000208:ethnology* / Q000378:metabolism; D008875:Middle Aged; D012307:Risk Factors; D055105:Waist Circumference / Q000502:physiology*