title: Organocatalytic, asymmetric synthesis of 3-sulfenylated N-Boc-protected oxindoles.
abstract: Sulfenylated oxindoles: The first asymmetric sulfenylation of N-Boc-protected oxindoles has been developed to provide products containing a tetrasubstituted stereogenic center in high to excellent yields (86-98 %) and, in most cases, excellent enantioselectivities (up to 96 % ee; see scheme).
authors: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074 Aachen, Germany.
authors: Chuan
authors: C
authors: Wang
authors: Xuena
authors: X
authors: Yang
authors: Charles C J
authors: CC
authors: Loh
authors: Gerhard
authors: G
authors: Raabe
authors: Dieter
authors: D
authors: Enders
mesh_terms: D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D000078183:Oxindoles; D011759:Pyrrolidines / Q000737:chemistry*; D013890:Thiourea / Q000031:analogs & derivatives / Q000737:chemistry*
chemical_list: D000577:Amides; D007211:Indoles; D000078183:Oxindoles; D011759:Pyrrolidines; C022960:2-oxindole; C010509:prolinol; D013890:Thiourea