title: Periodic fever as the manifestation of primary Sjogren's syndrome: a case report and literature review.
abstract: A 56-year-old male had periodic fever for 5 years and suffered from auditory hallucination and hearing impairment for 3 years. Xerostomia, xerophthalmia, elevated anti-SSA/Ro tilter, positive Schirmer's test, and lymphocyte infiltrate of mucoserous gland in lip biopsy of this case confirmed the diagnosis of primary Sjogren's syndrome (pSS). We review literature for fever and neuropsychiatric involvement in pSS case series. Though fever is present in 6-41 % pSS cases, periodic fever has not been reported. Auditory hallucination was rare in cases with pSS. The literature review alerts clinicians that fever and neurological manifestations were not uncommon in pSS cases.
authors: Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100, Tzyou 1st Road 807, Kaohsiung, Taiwan, China.
authors: Hui-Ching
authors: HC
authors: Wang
authors: Ko
authors: K
authors: Chang
authors: Chun-Yu
authors: CY
authors: Lin
authors: Yen-Hsu
authors: YH
authors: Chen
authors: Po-Liang
authors: PL
authors: Lu
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D015897:Comorbidity; D004008:Diclofenac / Q000627:therapeutic use; D010505:Familial Mediterranean Fever / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology*; D006212:Hallucinations / Q000175:diagnosis / Q000453:epidemiology; D034381:Hearing Loss / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac