title: Determination of bromate in drinking water by ultraperformance liquid chromatography-tandem mass spectrometry.
abstract: Bromate is a byproduct formed as a result of disinfection of bromide-containing source water with ozone or hypochlorite. The International Agency for Research on Cancer has recognized bromate as a possible human carcinogen, thus it is essential to determine in drinking water. Present work highlights a development of sensitive and fast analytical method for bromate determination in drinking water by using ultraperformance liquid chromatography-tandem mass spectrometry. The quality parameters of the developed method were established, obtaining very low limit of detection (0.01 ng/mL), repeatability and reproducibility have been found to be less than 3% in terms of relative standard deviation when analyzing a bromate standard at 0.05 μg/mL with 0.4 min analysis time. Developed method was applied for the analysis of metropolitan and bottled water from Saudi Arabia; 22 samples have been analyzed. Bromate was detected in the metropolitan water samples (from desalinization source) at concentrations ranging between 3.43 and 75.04 ng/mL and in the bottled water samples at concentrations ranging between 2.07 and 21.90 ng/mL. Moreover, in comparison to established analytical methods such as liquid chromatography-tandem mass spectrometry, the proposed method was found to be very sensitive, selective and rapid for the routine analysis of bromate at low level in drinking water.
authors: Advanced Materials Research Chair, Department of Chemistry, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia.
authors: Ibrahim Hotan
authors: IH
authors: Alsohaimi
authors: Zeid Abdullah
authors: ZA
authors: Alothman
authors: Mohammad Rizwan
authors: MR
authors: Khan
authors: Mohammad Abulhassan
authors: MA
authors: Abdalla
authors: Rosa
authors: R
authors: Busquets
authors: Ahmad Khodran
authors: AK
authors: Alomary
mesh_terms: D001959:Bromates / Q000032:analysis*; D002853:Chromatography, Liquid / Q000379:methods*; D060766:Drinking Water / Q000032:analysis*; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000032:analysis*; D014881:Water Supply / Q000032:analysis
chemical_list: D001959:Bromates; D060766:Drinking Water; D014874:Water Pollutants, Chemical