title: Chlamydia trachomatis infection among HIV-infected women attending an AIDS clinic in the city of Manaus, Brazil.
abstract: This was a cross-sectional study aimed to determine the prevalence of and to identify risk factors for Chlamydia trachomatis (CT) among human immunodeficiency virus (HIV)-infected women attending the acquired immunodeficiency syndrome (AIDS) clinic in the city of Manaus, Brazil, in 2009-2010. Participants answered a questionnaire containing demographic, epidemiological, and clinical data. A genital specimen was collected during examination to detect CT-DNA by hybrid capture, and blood samples were taken to determine CD4(+)T and HIV viral load. There were 329 women included in the study. Median age was 32 years (IQR=27-38) and median schooling was nine years (IQR=4-11). The prevalence of CT was 4.3% (95%CI: 2.1-6.5). Logistic regression analysis showed that age between 18-29 years [OR=4.1(95%CI: 1.2-13.4)] and complaint of pelvic pain [OR=3.7 (95%CI: 1.2-12.8)] were independently associated with CT. The use of condom was inversely associated with CT [OR=0.39 (95%CI: 0.1-0.9)]. The results showed that younger women who did not use condoms are at a higher risk for CT. Screening for sexually transmitted infections must be done routinely and safe sexual practices should be promoted among this population.
authors: Fundação de Medicina Tropical do Amazonas, Manaus, AM, Brazil. leilac@fmt.am.gov.br
authors: Leila Cristina Ferreira
authors: LC
authors: Silva
authors: Angélica Espinosa
authors: AE
authors: Miranda
authors: Rosieny Santos
authors: RS
authors: Batalha
authors: Carolina Cristina Dantas
authors: CC
authors: Sabino
authors: Elizabeth
authors: E
authors: Dib
authors: Carolina Marinho da
authors: CM
authors: Costa
authors: Rajendranath
authors: R
authors: Ramasawmy
authors: Sinésio
authors: S
authors: Talhari
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D001938:Brazil / Q000453:epidemiology; D018791:CD4 Lymphocyte Count; D002690:Chlamydia Infections / Q000453:epidemiology*; D002692:Chlamydia trachomatis; D003430:Cross-Sectional Studies; D004522:Educational Status; D005260:Female; D006801:Humans; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D019562:Viral Load; D055815:Young Adult