title: A supramolecular route towards core-shell polymeric microspheres in water via cucurbit[8]uril complexation.
abstract: Core-shell polymeric microspheres with a cleavable shell were prepared in water using cucurbit[8]uril to bring together functional polymeric microspheres and functional polymers. This supramolecular approach was employed to switch the cytotoxicity of the polymeric microspheres, leading to potential applications in the eradication of cancer cells.
authors: Melville Laboratory for Polymer Synthesis, Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK.
authors: Yang
authors: Y
authors: Lan
authors: Xian Jun
authors: XJ
authors: Loh
authors: Jin
authors: J
authors: Geng
authors: Zarah
authors: Z
authors: Walsh
authors: Oren A
authors: OA
authors: Scherman
mesh_terms: D000218:Adamantane / Q000031:analogs & derivatives; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001952:Bridged-Ring Compounds / Q000737:chemistry*; D002470:Cell Survival / Q000187:drug effects; D003692:Delayed-Action Preparations / Q000138:chemical synthesis* / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D007093:Imidazoles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D008863:Microspheres; D010269:Paraquat / Q000737:chemistry* / Q000633:toxicity; D010316:Particle Size; D011108:Polymers / Q000737:chemistry*; D013696:Temperature; D014867:Water; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils
chemical_list: D000218:Adamantane; D000970:Antineoplastic Agents; D001952:Bridged-Ring Compounds; D003692:Delayed-Action Preparations; D007093:Imidazoles; D010269:Paraquat; D011108:Polymers; D014867:Water; C507198:cucurbit(8)uril; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils