title: Calcaneal quantitative ultrasound compared with hip and femoral neck dual-energy x-ray absorptiometry in people with a spinal cord injury.
abstract: OBJECTIVE
  To evaluate the sensitivity and specificity of calcaneal quantitative ultrasound (QUS) measurements for identifying osteoporosis determined by dual-energy x-ray absorptiometry (DXA) at the hip in a spinal cord injury (SCI) population.
  
  
  METHODS
  Cross-sectional retrospective review of data collected in the bone health registry of persons with a disability.
  
  
  METHODS
  Inpatients and outpatients at a single acute rehabilitation hospital.
  
  
  METHODS
  A convenience sample of 66 participants, both inpatients and outpatients, with a spinal cord injury.
  
  
  METHODS
  Calcaneal T scores were determined by ultrasound, and bone density of the lumbar spine, total hip, and femoral neck were determined by DXA.
  
  
  METHODS
  Right and left calcaneal QUS T scores and right and left hip and femoral neck DXA T scores.
  
  
  RESULTS
  Right and left hip DXA T scores were strongly associated with corresponding right and left calcaneal QUS T scores (right: r = .72, P < .001; left: r = .70, P < .001). Similar associations were found when we evaluated femoral neck T scores and calcaneal QUS T scores. Receiver operating characteristic analysis for evaluating QUS to identify DXA-defined osteoporosis demonstrated an area under the curve of 0.81 for all participants (acute and chronic injury) and 0.68 for those with a chronic SCI.
  
  
  CONCLUSIONS
  A strong association exists between calcaneal QUS T scores and bone density T scores at the hip measured by DXA. QUS may have a place in the screening of people with SCI 1 year or more after their injury to evaluate their bone status.
authors: Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine, 710 N Lake Shore Drive, Room 1020, Chicago, IL 60611, USA. tjs@northwestern.edu
authors: Thomas J
authors: TJ
authors: Schnitzer
authors: Nicole
authors: N
authors: Wysocki
authors: Danielle
authors: D
authors: Barkema
authors: James
authors: J
authors: Griffith
authors: Victoria
authors: V
authors: Lent
authors: Meghan
authors: M
authors: Romba
authors: Rachel
authors: R
authors: Welbel
authors: Sheena
authors: S
authors: Bhuva
authors: Bindu
authors: B
authors: Manyam
authors: Sarah
authors: S
authors: Linn
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D015519:Bone Density / Q000502:physiology; D002111:Calcaneus / Q000000981:diagnostic imaging*; D003430:Cross-Sectional Studies; D005260:Female; D005272:Femur Neck / Q000000981:diagnostic imaging*; D006621:Hip Joint / Q000000981:diagnostic imaging*; D006801:Humans; D016015:Logistic Models; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D008297:Male; D010024:Osteoporosis / Q000175:diagnosis*; D012372:ROC Curve; D012042:Registries; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013119:Spinal Cord Injuries / Q000503:physiopathology*; D014463:Ultrasonography