title: DELIMINATE--a fast and efficient method for loss-less compression of genomic sequences: sequence analysis.
abstract: CONCLUSIONS
  An unprecedented quantity of genome sequence data is currently being generated using next-generation sequencing platforms. This has necessitated the development of novel bioinformatics approaches and algorithms that not only facilitate a meaningful analysis of these data but also aid in efficient compression, storage, retrieval and transmission of huge volumes of the generated data. We present a novel compression algorithm (DELIMINATE) that can rapidly compress genomic sequence data in a loss-less fashion. Validation results indicate relatively higher compression efficiency of DELIMINATE when compared with popular general purpose compression algorithms, namely, gzip, bzip2 and lzma.
  
  
  METHODS
  Linux, Windows and Mac implementations (both 32 and 64-bit) of DELIMINATE are freely available for download at: http://metagenomics.atc.tcs.com/compression/DELIMINATE.
  
  
  BACKGROUND
  sharmila@atc.tcs.com
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors: Bio-sciences R&D Division, TCS Innovation Labs, Tata Consultancy Services Limited, 1 Software Units Layout, Madhapur, Hyderabad 500081, Andhra Pradesh, India.
authors: Monzoorul Haque
authors: MH
authors: Mohammed
authors: Anirban
authors: A
authors: Dutta
authors: Tungadri
authors: T
authors: Bose
authors: Sudha
authors: S
authors: Chadaram
authors: Sharmila S
authors: SS
authors: Mande
mesh_terms: D000465:Algorithms; D001483:Base Sequence; D019295:Computational Biology / Q000379:methods*; D044962:Data Compression / Q000379:methods*; D023281:Genomics / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods