title: Local anesthetics: review of pharmacological considerations.
abstract: Local anesthetics have an impressive history of efficacy and safety in medical and dental practice. Their use is so routine, and adverse effects are so infrequent, that providers may understandably overlook many of their pharmacotherapeutic principles. The purpose of this continuing education article is to provide a review and update of essential pharmacology for the various local anesthetic formulations in current use. Technical considerations will be addressed in a subsequent article.
authors: General Dental Practice Residency, Miami Valley Hospital, Dayton, Ohio, 45409, USA.debecker@mvh.org
authors: Daniel E
authors: DE
authors: Becker
authors: Kenneth L
authors: KL
authors: Reed
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology; D000762:Anesthesia Recovery Period; D000766:Anesthesia, Dental / Q000379:methods; D000772:Anesthesia, Local; D000779:Anesthetics, Local / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D002355:Carticaine / Q000494:pharmacology; D004342:Drug Hypersensitivity; D004347:Drug Interactions; D006801:Humans; D008012:Lidocaine / Q000494:pharmacology; D020714:Maximum Tolerated Dose; D010646:Phentolamine / Q000494:pharmacology; D014662:Vasoconstrictor Agents / Q000494:pharmacology
chemical_list: D000317:Adrenergic alpha-Antagonists; D000779:Anesthetics, Local; D014662:Vasoconstrictor Agents; D008012:Lidocaine; D002355:Carticaine; D010646:Phentolamine