title: Synthesis of biologically active bridged diazabicycloheptanes.
abstract: The chemistry underlying how diazabicycloheptanes are assembled is described, subdivided according to chemical structure of two types, the 3,6 diazabicyclo[3.1.1]heptane and the 2,5-diazabicyclo[2.2.1]heptane ring system. Detailed information on myriad of activities of compounds derived from the two scaffolds are reported.
authors: Department of Chemistry and Pharmacy, University of Sassari, via F. Muroni 23/A, 07100 Sassari, Italy. muri@uniss.it
authors: G
authors: G
authors: Murineddu
authors: B
authors: B
authors: Asproni
authors: G
authors: G
authors: Pinna
authors: M M
authors: MM
authors: Curzu
authors: A
authors: A
authors: Dore
authors: A
authors: A
authors: Pau
authors: F
authors: F
authors: Deligia
authors: G A
authors: GA
authors: Pinna
mesh_terms: D000700:Analgesics / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D014150:Antipsychotic Agents / Q000138:chemical synthesis / Q000737:chemistry; D001372:Aza Compounds / Q000737:chemistry*; D001419:Bacteria / Q000187:drug effects; D001952:Bridged-Ring Compounds / Q000737:chemistry*; D004791:Enzyme Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D006536:Heptanes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D007166:Immunosuppressive Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding
chemical_list: D000700:Analgesics; D000900:Anti-Bacterial Agents; D014150:Antipsychotic Agents; D001372:Aza Compounds; D001952:Bridged-Ring Compounds; D004791:Enzyme Inhibitors; D006536:Heptanes; D007166:Immunosuppressive Agents