title: [High-density lipoproteins as a form of daunorubicin transport in hepatoma cells of mice].
abstract: The efficiency of using high-density lipoproteins (HDLPs) as the transport form of an antineoplastic drug daunorubicin (rubomycin hydrochloride, daunoxome) has been shown on the culture of HA-1 hepatoma cells of mice. The use of HDLPs in a complex with daunorubicin led to an increase in the efficiency of drug transport and cytotoxic action with respect to tumor cells in comparison with hepatocytes of healthy animals.
authors: D V
authors: DV
authors: Sumenkova
authors: L M
authors: LM
authors: Poliakov
authors: L E
authors: LE
authors: Panin
mesh_terms: D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000493:pharmacokinetics*; D001692:Biological Transport; D045744:Cell Line, Tumor; D003630:Daunorubicin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D004337:Drug Carriers / Q000737:chemistry / Q000493:pharmacokinetics*; D008075:Lipoproteins, HDL / Q000737:chemistry / Q000378:metabolism*; D051379:Mice; D009369:Neoplasms / Q000378:metabolism*; D051381:Rats
chemical_list: D000903:Antibiotics, Antineoplastic; D004337:Drug Carriers; D008075:Lipoproteins, HDL; D003630:Daunorubicin