title: Augmented ocular vestibular evoked myogenic potentials to air-conducted sound in large vestibular aqueduct syndrome.
abstract: OBJECTIVE
  To demonstrate the value of recording air-conducted ocular Vestibular Evoked Myogenic Potentials (oVEMP) in a patient with bilaterally enlarged vestibular aqueducts.
  
  
  METHODS
  Cervical VEMP and oVEMP were recorded from a patient presenting with bilateral hearing loss and imbalance, attributable to large vestibular aqueduct syndrome. The stimuli were air-conducted tone bursts at octave frequencies from 250 to 2000 Hz. Amplitudes and thresholds were measured and compared with the normal response range of 32 healthy control subjects.
  
  
  RESULTS
  oVEMP reflexes demonstrated pathologically increased amplitudes and reduced thresholds for low-frequency tone bursts. Cervical VEMP amplitudes and thresholds were within normal limits for both ears across all frequencies of stimulation.
  
  
  CONCLUSIONS
  This study is the first to describe the augmentation of AC oVEMPs in an adult with large vestibular aqueduct syndrome.
authors: Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, NSW, Australia.
authors: Rachael L
authors: RL
authors: Taylor
authors: Andrew P
authors: AP
authors: Bradshaw
authors: John S
authors: JS
authors: Magnussen
authors: William P R
authors: WP
authors: Gibson
authors: G Michael
authors: GM
authors: Halmagyi
authors: Miriam S
authors: MS
authors: Welgampola
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000503:physiopathology*; D006801:Humans; D010037:Otolithic Membrane / Q000503:physiopathology; D004856:Postural Balance / Q000502:physiology; D012021:Reflex, Abnormal / Q000502:physiology*; D013018:Sound Spectrography; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D014723:Vestibular Aqueduct / Q000002:abnormalities / Q000503:physiopathology; D058585:Vestibular Evoked Myogenic Potentials / Q000502:physiology*