title: Hepatitis C virus infection in patients with hemophilia in Isfahan, Iran.
abstract: OBJECTIVE
  Patients with hereditary bleeding disorders are at risk of viral infection such as hepatitis C due to frequent transfusion of blood and blood products. This study aimed to determine the prevalence of hepatitis C and associated risk factors in hemophilic patients in Isfahan, the second big province in Iran.
  
  
  METHODS
  In a descriptive study, patients with hemophilia in Isfahan province were enrolled. A questionnaire, including demographic and risk factors of hepatitis C was completed through a structured interview with closed questions by a trained interviewer for each patient and HCV-Ab test results were extracted from patient records.
  
  
  RESULTS
  In this study, 232 of 350 patients with hemophilia A and B (66%) were positive for hepatitis C. Based on Multivariate Logistic Regression model, no independent risk factor was found.
  
  
  CONCLUSIONS
  Prevalence of hepatitis C in patients with haemophilia A and B in Isfahan is high. Since no independent risk factor for hepatitis C disease was found in this high risk group, it can be concluded that multitransfusion is the only predictor for hepatitis C.
authors: Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: Mohammad Reza
authors: MR
authors: Yazdani
authors: Nazila
authors: N
authors: Kassaian
authors: Behrooz
authors: B
authors: Ataei
authors: Zary
authors: Z
authors: Nokhodian
authors: Peyman
authors: P
authors: Adibi