title: Development of a new platform for neglected tropical disease surveillance.
abstract: An expanded global focus on the control and elimination of neglected tropical diseases (NTDs) has called attention to the need to develop and validate surveillance strategies that are cost effective and can be integrated across diseases. Here, we describe a multiplex tool for the sensitive detection of antibody responses to NTDs as well as vaccine preventable diseases, malaria, and waterborne and zoonotic infections. The assay platform is robust, can be performed with either serum or dried blood spots and can be adapted to local epidemiological conditions and public health priorities. Multiplex assays open the door to conducting routine serosurveillance for NTDs through demographic health surveillance or malaria indicator surveys.
authors: Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA. plammie@cdc.gov
authors: Patrick J
authors: PJ
authors: Lammie
authors: Delynn M
authors: DM
authors: Moss
authors: E
authors: E
authors: Brook Goodhew
authors: Katy
authors: K
authors: Hamlin
authors: Alejandro
authors: A
authors: Krolewiecki
authors: Sheila K
authors: SK
authors: West
authors: Jeffrey W
authors: JW
authors: Priest
mesh_terms: D000906:Antibodies / Q000097:blood*; D000941:Antigens; D001424:Bacterial Infections / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control; D015415:Biomarkers; D006801:Humans; D008863:Microspheres; D058069:Neglected Diseases / Q000175:diagnosis* / Q000453:epidemiology* / Q000517:prevention & control; D010272:Parasitic Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control; D011159:Population Surveillance / Q000379:methods*; D012680:Sensitivity and Specificity; D014329:Tropical Climate; D014612:Vaccines / Q000276:immunology; D014777:Virus Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control
chemical_list: D000906:Antibodies; D000941:Antigens; D015415:Biomarkers; D014612:Vaccines