title: Abnormal loading of the major joints in knee osteoarthritis and the response to knee replacement.
abstract: Knee osteoarthritis is common and patients frequently complain that they are 'overloading' the joints of the opposite leg when they walk. However, it is unknown whether moments or co-contractions are abnormal in the unaffected joints of patients with single joint knee osteoarthritis, or how they change following treatment of the affected knee. Twenty patients with single joint medial compartment knee osteoarthritis were compared to 20 asymptomatic control subjects. Gait analysis was performed for normal level gait and surface EMG recordings of the medial and lateral quadriceps and hamstrings were used to investigate co-contraction. Patients were followed up 12 months post-operatively and the analysis was repeated. Results are presented for the first 14 patients who have attended follow-up. Pre-operatively, adduction moment impulses were elevated at both knees and the contra-lateral hip compared to controls. Co-contraction of hamstrings and quadriceps was elevated bilaterally. Post-operatively, moment waveforms returned to near-normal levels at the affected knee and co-contraction fell in the majority of patients. However, abnormalities persisted in the contra-lateral limb with partial or no recovery of both moment waveforms and co-contraction in the majority. Patients with knee osteoarthritis do experience abnormal loads of their major weight bearing joints bilaterally, and abnormalities persist despite treatment of the affected limb. Further treatment may be required if we are to protect the other major joints following joint arthroplasty.
authors: Betsi Cadwaladr University Health Board, North Wales, UK. ametcalfe@doctors.org.uk
authors: Andrew
authors: A
authors: Metcalfe
authors: Caroline
authors: C
authors: Stewart
authors: Neil
authors: N
authors: Postans
authors: David
authors: D
authors: Barlow
authors: Alexander
authors: A
authors: Dodds
authors: Cathy
authors: C
authors: Holt
authors: Gemma
authors: G
authors: Whatling
authors: Andrew
authors: A
authors: Roberts
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000534:rehabilitation*; D001696:Biomechanical Phenomena; D016022:Case-Control Studies; D004576:Electromyography; D005260:Female; D005684:Gait; D006621:Hip Joint; D006801:Humans; D007596:Joints / Q000503:physiopathology*; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000503:physiopathology*; D020370:Osteoarthritis, Knee / Q000503:physiopathology* / Q000534:rehabilitation / Q000601:surgery*; D016474:Weight-Bearing