title: [The contribution of parameters of subclinical artery wall  damage in the evaluation of cardiovascular risk].
abstract: OBJECTIVE
  To assess contribution of such parameters as intima-media thickness (IMT), presence of carotid plagues (ab), pulse wave velocity (abPWV) and ankle-brachial index (ABI) to asessment of cardiovascular risk in patients who were initially assigned to the group of low and moderate risk according to the SCORE scale.
  
  
  METHODS
  600 patients with low and moderate cardiovascular risk according to "SCORE" scale were selected: 445 women and 155 men in the age 30-65 years. We used color duplex ultrasound imaging (DUI) of carotid arteries (CA),. computer sphigmography (CS), biochemical tests (lipid profile. MDRD. glucose).
  
  
  RESULTS
  The contribution of studied methods to risk stratification was compared: DUI of CA allowed to find patients with subclinical artery wall damage in 96%, CS-abPWV - in 39%, and ABI only - in 5% of cases. After adding abPWV to patient examination 61% remained in the low risk group and 17% were converted into the high risk group. At the same time after adding DUI of CA only 37% of patients remained in the low risk group and 36% (almost every third) were converted to more high risk group.
  
  
  CONCLUSIONS
  The most sensitive method of detection subclinical artery wall damages is duplex ultrasound imaging of CA. The abPWV also has some diagnostic value and can be recommended to find out this kind of damage due to its simplicity and convenience.
authors: S Zh
authors: SZh
authors: Urazalina
authors: A N
authors: AN
authors: Rogoza
authors: T V
authors: TV
authors: Balakhonova
authors: V V
authors: VV
authors: Kukharchuk
authors: Iu A
authors: IuA
authors: Karpov
authors: S A
authors: SA
authors: Boĭtsov
mesh_terms: D000328:Adult; D055109:Ankle Brachial Index / Q000379:methods; D058070:Asymptomatic Diseases; D001783:Blood Flow Velocity; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D059168:Carotid Intima-Media Thickness; D016893:Carotid Stenosis / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011673:Pulsatile Flow; D018570:Risk Assessment; D012307:Risk Factors; D012680:Sensitivity and Specificity; D017539:Tunica Intima / Q000473:pathology / Q000503:physiopathology; D017540:Tunica Media / Q000473:pathology / Q000503:physiopathology; D018616:Ultrasonography, Doppler, Duplex / Q000379:methods*