title: Coarctate cyclization reactions: a primer.
abstract: The cleavage of five-membered heterocycles possessing an exocyclic carbene or nitrene to form conjugated ene-ene-yne systems has been documented for over 40 years; however, the reverse reaction, using a conjugated "ene-ene-yne" precursor to form a heterocycle is a relatively new approach. Over the past decade, the Haley and Herges groups have studied computationally and experimentally the cyclization of the "hetero-ene-ene-yne" motif via an unusual class of concerted reactions known as coarctate reactions. This feature article details our synthetic and mechanistic work involving triazene-arene-alkynes and structurally-related systems to generate heterocycles using coarctate chemistry.
authors: University of Oregon-Department of Chemistry, Eugene, Oregon 97403-1253, USA.
authors: Brian S
authors: BS
authors: Young
authors: Rainer
authors: R
authors: Herges
authors: Michael M
authors: MM
authors: Haley