title: A review on creatinine measurement techniques.
abstract: This paper reviews the entire recent global tendency for creatinine measurement. Creatinine biosensors involve complex relationships between biology and micro-mechatronics to which the blood is subjected. Comparison between new and old methods shows that new techniques (e.g. Molecular Imprinted Polymers based algorithms) are better than old methods (e.g. Elisa) in terms of stability and linear range. All methods and their details for serum, plasma, urine and blood samples are surveyed. They are categorized into five main algorithms: optical, electrochemical, impedometrical, Ion Selective Field-Effect Transistor (ISFET) based technique and chromatography. Response time, detection limit, linear range and selectivity of reported sensors are discussed. Potentiometric measurement technique has the lowest response time of 4-10 s and the lowest detection limit of 0.28 nmol L(-1) belongs to chromatographic technique. Comparison between various techniques of measurements indicates that the best selectivity belongs to MIP based and chromatographic techniques.
authors: The Center of Excellence for Mechatronics, School of Engineering Emerging Technologies, University of Tabriz, Tabriz, Iran.
authors: Elham
authors: E
authors: Mohabbati-Kalejahi
authors: Vahid
authors: V
authors: Azimirad
authors: Manouchehr
authors: M
authors: Bahrami
authors: Ahmad
authors: A
authors: Ganbari
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D003404:Creatinine / Q000032:analysis* / Q000097:blood / Q000378:metabolism / Q000652:urine; D005919:Glomerular Filtration Rate; D006801:Humans; D014159:Transducers
chemical_list: D003404:Creatinine