title: Posterior laryngitis: a study of persisting symptoms and health-related quality of life.
abstract: Posterior laryngitis is a common cause of chronic cough, hoarseness, voice fatigue and throat pain. The aim of the present study was to examine how patients with posterior laryngitis have been examined, treated and followed up, and to assess their present health-related quality of life (HRQOL). Patients treated for posterior laryngitis at consultation at the ear-, nose- and throat clinic during 2000-2008 were contacted by mail. The letter contained questionnaires addressing the current symptoms and medication, and the HRQOL 36-item short-form questionnaire (SF-36). Medical records were scrutinized. One hundred and twenty-two patients with verified signs and symptoms of posterior laryngitis were included. Forty percent of the patients had been treated for acid-related symptoms prior to consultation. The most common symptoms at the time of consultation were the sensation of hoarseness (women 40 %, men 37 %), globus (women 35 %, men 33 %) and cough (women 33 %, men 26 %). The most frequent diagnosis was gastro-oesophageal reflux disease. Ninety percent of the women and 92 % of the men were treated with proton pump inhibitors (PPIs). At the time of study, 63 % of the patients still had symptoms. The results of the SF-36 questionnaire showed significantly lower HRQOL for women. Patients with posterior laryngitis present varying symptoms, and are often not adequately treated or followed up. When PPI treatment fails, other aetiologies of their complaints, such as visceral hypersensitivity, weakly gaseous acid reflux or non-acid reflux are not considered. Symptoms from posterior laryngitis have a negative impact on the HRQOL for women.
authors: Division of Oto-Rhino-Laryngology, Department of Clinical Sciences, Skåne University Hospital, Malmö, Lund University, Jan Waldenströmsgata 18, 20502, Malmö, Sweden. Hillevi.Pendleton@med.lu.se
authors: Hillevi
authors: H
authors: Pendleton
authors: Marianne
authors: M
authors: Ahlner-Elmqvist
authors: Magnus
authors: M
authors: Jannert
authors: Bodil
authors: B
authors: Ohlsson
mesh_terms: D005260:Female; D006801:Humans; D007827:Laryngitis / Q000209:etiology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012307:Risk Factors; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D016896:Treatment Outcome