title: Changes in electrokinetic properties of erythrocytes under the influence of pentoxifylline and new hemorheologically active substances.
abstract: We studied the impact of compounds RU-1202 and SUM-55 on electrophoretic mobility of "young" and "old" erythrocytes fractionated in a density gradient. The test compounds are shown to increase electrophoretic mobility of erythrocytes, compound SUM-55 being superior to the reference drug pentoxifylline.
authors: Department of Pharmacology, Volgograd State Medical University, Rostov-on-Don, Russia. milanaumenko@mail.ru
authors: L V
authors: LV
authors: Naumenko
authors: V A
authors: VA
authors: Kuznetsov
authors: A A
authors: AA
authors: Spasov
authors: A V
authors: AV
authors: Muravyev
authors: I A
authors: IA
authors: Tikhomirova
authors: F A
authors: FA
authors: Khaliullin
authors: V A
authors: VA
authors: Anisimova
mesh_terms: D000818:Animals; D001562:Benzimidazoles / Q000494:pharmacology*; D004591:Electrophoresis, Polyacrylamide Gel; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000502:physiology; D004912:Erythrocytes / Q000187:drug effects* / Q000502:physiology*; D008297:Male; D010431:Pentoxifylline / Q000494:pharmacology*; D010880:Piperidines / Q000494:pharmacology*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology; D051381:Rats; D014970:Xanthines / Q000494:pharmacology*
chemical_list: C577766:1,3-dimethyl-7-(2-hydroxy-3-(1-piperidino)propyl)-8-phenylxanthineamine; C577765:9-(2-diethylaminoethyl)-2-(4-fluorophenyl)imidazo(1,2-a)benzimidazole; D001562:Benzimidazoles; D010880:Piperidines; D010975:Platelet Aggregation Inhibitors; D014970:Xanthines; D010431:Pentoxifylline