title: The important role of inflammatory biomarkers pre and post bare-metal and drug-eluting stent implantation.
abstract: In-stent restenosis and stent thrombosis are major complications after percutaneous coronary intervention and coronary stent placement. The inflammatory status of an individual, as reflected by biomarkers and genetic polymorphisms, is a strong predictor of the risk of in-stent restenosis and stent thrombosis. Identifying biomarkers and studying their values are crucial for a more efficient personalized intervention. General inflammatory biomarkers, evidence of inflammation, and the difference between inflammatory biomarkers after bare-metal stent and drug-eluting stent placement are discussed. Clinical implications and the use of antiplatelet and anti-inflammatory medications, as well as future directions in coronary intervention, in reducing the occurrence of these complications, are also discussed.
authors: Department of Medicine, Division of Cardiovascular Diseases, University of Tennessee Health Science Center, 6283 Common Oaks Crt # 106, Memphis, TN 38120, USA. khouzamrami@yahoo.com
authors: Rami N
authors: RN
authors: Khouzam
authors: Mazen
authors: M
authors: Shaheen
authors: Ramy K
authors: RK
authors: Aziz
authors: Uzoma N
authors: UN
authors: Ibebuogu
mesh_terms: D015415:Biomarkers / Q000097:blood*; D023903:Coronary Restenosis / Q000097:blood / Q000453:epidemiology / Q000517:prevention & control; D054855:Drug-Eluting Stents; D006801:Humans; D007249:Inflammation / Q000097:blood*; D062645:Percutaneous Coronary Intervention; D011184:Postoperative Period; D057234:Preoperative Period; D011379:Prognosis
chemical_list: D015415:Biomarkers