title: A comparison of suboxone and clonidine treatment outcomes in opiate detoxification.
abstract: OBJECTIVE
  This retrospective quality improvement study was to evaluate if Suboxone therapy reduced the risk of terminating treatment against medical advice compared with the use clonidine in men aged 18--55 years.
  
  
  METHODS
  Data were collected through chart review for all opioid-addicted male clients admitted voluntarily to a community-based treatment center between July 1, 2009, and December 30, 2009.
  
  
  RESULTS
  The chi-square test of independence between treatment completion and treatment noncompletion was found to be significant at the 5% critical level (P = .027) for Suboxone therapy.
  
  
  CONCLUSIONS
  Suboxone treatment decreased premature termination of opioid detoxification completion when compared with clonidine.
authors: Mary Dee Lane Winston-Salem, NC, USA. asbsn@aol.com
authors: Anthony
authors: A
authors: Steele
authors: Patricia
authors: P
authors: Cunningham
mesh_terms: D000293:Adolescent; D058647:Adrenergic alpha-2 Receptor Agonists / Q000009:adverse effects / Q000627:therapeutic use*; D000328:Adult; D002047:Buprenorphine / Q000009:adverse effects / Q000627:therapeutic use*; D000069479:Buprenorphine, Naloxone Drug Combination; D003000:Clonidine / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009270:Naloxone / Q000009:adverse effects / Q000627:therapeutic use*; D009292:Narcotic Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D009293:Opioid-Related Disorders / Q000451:nursing* / Q000534:rehabilitation*; D010352:Patient Dropouts / Q000523:psychology; D058996:Quality Improvement; D012047:Rehabilitation Centers; D012189:Retrospective Studies; D012306:Risk; D055815:Young Adult
chemical_list: D058647:Adrenergic alpha-2 Receptor Agonists; D000069479:Buprenorphine, Naloxone Drug Combination; D009292:Narcotic Antagonists; D009270:Naloxone; D002047:Buprenorphine; D003000:Clonidine