title: Development of a difenoconazole/propiconazole microemulsion and its antifungal activities against Rhizoctonia solani AG1-IA.
abstract: According to its physical and chemical properties, the composition of difenoconazole/propiconazole microemulsion was as follows: xylene as solvent, emulsifier HSH as surfactant and methanol as cosurfactant. The optimal formulation of difenoconazole/propiconazole microemulsion was oil/SAA/water = 1/2/5 (w/w), in which the SAA consisted of emulsifier HSH and methanol with ratio of 3/2 (w/w). The cloud point of difenoconazole/propiconazole microemulsion was 70 degrees C and its effective ingredient content was 2.5% measured by High Performance Liquid Chromatography (HPLC). Its heat storage stability was studied according to the standards. The decomposition rates of the difenoconazole/propiconazole microemulsion were merely 2.45%, 2.63% respectively and met the Food and Agriculture Organization (FAO) standards of pesticide microemulsion. Investigated by Transmission Electron Microscopy (TEM) the particle size of difenoconazole/propiconazole microemulsion was 90-140 nm and its antifungal activities against Rhizoctonia solani AG1-IA were tested and compared with that of Meiyu. We found that the inhibition rates in the difenoconazole/propiconazole microemulsion treatment group were significantly higher than that of the emulsion group with the same content of effective ingredients and the study also revealed that its inhibiting ability on the formation and germination of sclerotia was significant.
authors: Key Laboratory of Biology and Genetic Improvement of Maize for Southwest China, Ministry of Agriculture, Maize Research Institute, Sichuan Agricultural University, Ya'an, PR China.
authors: Pengfei
authors: P
authors: Leng
authors: Zhiming
authors: Z
authors: Zhang
authors: Qian
authors: Q
authors: Li
authors: Yunsong
authors: Y
authors: Zhang
authors: Maojun
authors: M
authors: Zhao
authors: Guangtang
authors: G
authors: Pan
mesh_terms: D000465:Algorithms; D004148:Dioxolanes / Q000008:administration & dosage* / Q000737:chemistry / Q000494:pharmacology*; D004655:Emulsions; D005659:Fungicides, Industrial / Q000008:administration & dosage* / Q000737:chemistry / Q000494:pharmacology*; D000432:Methanol; D008826:Microbial Sensitivity Tests; D046529:Microscopy, Electron, Transmission; D010316:Particle Size; D012232:Rhizoctonia / Q000187:drug effects*; D012997:Solvents; D013501:Surface-Active Agents; D014230:Triazoles / Q000008:administration & dosage* / Q000737:chemistry / Q000494:pharmacology*; D014992:Xylenes
chemical_list: D004148:Dioxolanes; D004655:Emulsions; D005659:Fungicides, Industrial; D012997:Solvents; D013501:Surface-Active Agents; D014230:Triazoles; D014992:Xylenes; C045950:propiconazole; C115058:difenoconazole; D000432:Methanol