title: Complete genome sequence of Staphylococcus aureus bacteriophage GH15.
abstract: GH15 is a polyvalent phage that shows activity against a wide range of Staphylococcus aureus strains. In this work, the complete genome sequence of GH15 was determined. With a genome size of 139,806 bp (double-stranded DNA), GH15 is the largest staphylococcal phage sequenced to date. The complete genome encodes 214 open reading frames (ORFs) and 4 tRNAs. The closest relatives are the class III staphylococcal myobacteriophages, including K, A5W, ISP, Sb-1, and G1. Interestingly, although corresponding gene sequences demonstrate very high similarity, all the introns and inteins present in the phages listed above are absent in GH15. As such, GH15 can be considered phylogenetically unique among the staphylococcal myobacteriophages, indicating the diversity of this family.
authors: College of Animal Science and Veterinary Medicine, Jilin University, Changchun, People's Republic of China.
authors: Jingmin
authors: J
authors: Gu
authors: Xiaohe
authors: X
authors: Liu
authors: Rong
authors: R
authors: Lu
authors: Yue
authors: Y
authors: Li
authors: Jun
authors: J
authors: Song
authors: Liancheng
authors: L
authors: Lei
authors: Changjiang
authors: C
authors: Sun
authors: Xin
authors: X
authors: Feng
authors: Chongtao
authors: C
authors: Du
authors: Hao
authors: H
authors: Yu
authors: Yongjun
authors: Y
authors: Yang
authors: Wenyu
authors: W
authors: Han
mesh_terms: D001435:Bacteriophages / Q000235:genetics* / Q000302:isolation & purification; D004247:DNA / Q000235:genetics; D004279:DNA, Viral / Q000737:chemistry* / Q000235:genetics*; D016679:Genome, Viral; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010802:Phylogeny; D012343:RNA, Transfer / Q000235:genetics; D017422:Sequence Analysis, DNA; D013211:Staphylococcus aureus / Q000821:virology*
chemical_list: D004279:DNA, Viral; D004247:DNA; D012343:RNA, Transfer