title: DanteR: an extensible R-based tool for quantitative analysis of -omics data.
abstract: BACKGROUND
  The size and complex nature of mass spectrometry-based proteomics datasets motivate development of specialized software for statistical data analysis and exploration. We present DanteR, a graphical R package that features extensive statistical and diagnostic functions for quantitative proteomics data analysis, including normalization, imputation, hypothesis testing, interactive visualization and peptide-to-protein rollup. More importantly, users can easily extend the existing functionality by including their own algorithms under the Add-On tab.
  
  
  BACKGROUND
  DanteR and its associated user guide are available for download free of charge at http://omics.pnl.gov/software/. We have an updated binary source for the DanteR package up on our website together with a vignettes document. For Windows, a single click automatically installs DanteR along with the R programming environment. For Linux and Mac OS X, users must install R and then follow instructions on the DanteR website for package installation.
  
  
  BACKGROUND
  rds@pnnl.gov.
authors: Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA 99352, USA.
authors: Tom
authors: T
authors: Taverner
authors: Yuliya V
authors: YV
authors: Karpievitch
authors: Ashoka D
authors: AD
authors: Polpitiya
authors: Joseph N
authors: JN
authors: Brown
authors: Alan R
authors: AR
authors: Dabney
authors: Gordon A
authors: GA
authors: Anderson
authors: Richard D
authors: RD
authors: Smith
mesh_terms: D000465:Algorithms; D003627:Data Interpretation, Statistical; D013058:Mass Spectrometry; D011506:Proteins / Q000378:metabolism; D040901:Proteomics / Q000379:methods*; D012984:Software
chemical_list: D011506:Proteins