title: [A case of propranolol therapy for infantile capillary hemangiomas of the parotis].
abstract: A 4-month-old healthy female infant presented with rapid onset of subaural swelling over a three-month period. A head and neck exam demonstrated a subaural elastic hard mass with a red birthmark below the left auricle. MRI of the neck demonstrated a well-defined parotid mass consistent with a haemangioma. We treated this infant with 1 mg/kg of propranolol, which was gradually increased over two months to a dose of 2 mg/kg daily. The tumor began to reduce in size within three days after drug administration, and became less prominent in one month, and had almost totally disappeared within four months. On ten-month follow-up, the patient was asymptomatic and repeated MRI demonstrated further regression of the tumor. Propranolol could be the first-line choice for treating haemangioma rather than simple
authors: Department of Otorhinolaryngology, Head and Neck Surgery Faculty of medicine, University of Miyazaki.
authors: Shinya
authors: S
authors: Hirahara
authors: Keiji
authors: K
authors: Matsuda
authors: Katsuhiro
authors: K
authors: Toyama
authors: Yuki
authors: Y
authors: Nagano
authors: Noriaki
authors: N
authors: Nagai
authors: Tetsuya
authors: T
authors: Tono
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D005260:Female; D006258:Head and Neck Neoplasms / Q000188:drug therapy* / Q000473:pathology*; D018324:Hemangioma, Capillary / Q000188:drug therapy* / Q000473:pathology*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D009386:Neoplastic Syndromes, Hereditary / Q000188:drug therapy* / Q000473:pathology*; D011433:Propranolol / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D011433:Propranolol