title: [Chronic rhinosinusitis: epidemiology, classification, etiology, and pathogenesis. The current view of the problem].
abstract: The study of chronic rhinosinusitis is a challenging problem bearing in mind the ever-increasing morbidity and the lack of generally accepted criteria for diagnostics and treatment of this pathology. There is a great variety of factors predisposing to the development of chronic rhinosinusitis whereas its etiology remains controversial. Moreover, the pathogenetic mechanisms of chronic rhinosinusitis remain to be elucidated despite a wealth of publications devoted to this problem The results of many evidence-based investigations are different and even conflicting. Both diagnostic techniques and characteristics of chronic rhinosinusitis vary in a broad range depending on the standards adopted in different countries.
authors: O A
authors: OA
authors: Ivanchenko
authors: A S
authors: AS
authors: Lopatin
mesh_terms: D015984:Causality; D002908:Chronic Disease; D015897:Comorbidity; D006801:Humans; D009297:Nasal Mucosa / Q000473:pathology; D012220:Rhinitis / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy; D012852:Sinusitis / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy