title: [Relationship between traditional Chinese medicine syndrome types and serum HBV DNA level in chronic HBV carriers positive for HBeAg].
abstract: OBJECTIVE
  To explore the relationship between the syndrome types in traditional Chinese medicine (TCM) and serum HBV DNA load in chronic HBV carriers positive for HBeAg.
  
  
  METHODS
  According to the TCM syndrome types, 185 chronic HBV carriers with HBeAg positivity were classified into single syndrome group (liver Qi depression, kidney Qi deficiency, spleen Qi deficiency, and kidney Yang deficiency), compound syndrome group, and unidentifiable syndrome group; based on the nature of the condition in TCM terms, the patients were classified into excess syndrome group, deficiency syndrome group and comorbidity syndrome group. The serum HBV DNA levels in these cases were analyzed in relation to the TCM syndrome types and disease nature.
  
  
  RESULTS
  HBV DNA levels showed no significant difference among the patients with single syndrome, compound syndromes and unidentifiable syndrome (F=0.910, P=0.404), nor among the patients with the 5 different single TCM syndromes (χ²=4.672, P=0.323) or those with different disease nature (F=0.631, P=0.596).
  
  
  CONCLUSIONS
  Serum HBV DNA level can not be considered as the evidence for syndrome differentiation in chronic HBV carriers with positive HBeAg.
authors: Department of Traditional Chinese Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China. sunyetsun@126.com
authors: Heping
authors: H
authors: Xie
authors: Hongzhi
authors: H
authors: Yang
authors: Weikang
authors: W
authors: Wu
authors: Weibing
authors: W
authors: Guan
authors: Qianshan
authors: Q
authors: Ke
authors: Yongwei
authors: Y
authors: Li
authors: Min
authors: M
authors: Dai
authors: Gemin
authors: G
authors: Xiao
authors: Yangmei
authors: Y
authors: Li
authors: Jiongshan
authors: J
authors: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D002353:Carrier State / Q000097:blood / Q000175:diagnosis*; D002648:Child; D004279:DNA, Viral / Q000097:blood; D005260:Female; D006513:Hepatitis B e Antigens / Q000097:blood; D006515:Hepatitis B virus / Q000235:genetics; D019694:Hepatitis B, Chronic / Q000097:blood / Q000175:diagnosis* / Q000821:virology*; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D055815:Young Adult
chemical_list: D004279:DNA, Viral; D006513:Hepatitis B e Antigens