title: 1000 liver transplantations at the Department of General, Transplant and Liver Surgery, Medical University of Warsaw--analysis of indications and results.
abstract: OBJECTIVE
  was to analyze indications and results of the first one thousand liver transplantations at Chair and Clinic of General, Transplantation and Liver Surgery, Medical University of Warsaw.
  
  
  METHODS
  Data from 1000 transplantations (944 patients) performed at Chair and Clinic of General, Transplantation and Liver Surgery between 1994 and 2011 were analyzed retrospectively. These included 943 first transplantations and 55 retransplantations and 2 re-retransplantations. Frequency of particular indications for first transplantation and retransplantations was established. Perioperative mortality was defined as death within 30 days after the transplantation. Kaplan-Meier survival analysis was used to estimate 5-year patient and graft survival.
  
  
  RESULTS
  The most common indications for first transplantation included: liver failure caused by hepatitis C infection (27.8%) and hepatitis B infection (18%) and alcoholic liver disease (17.7%). Early (< 6 months) and late (> 6 months) retransplantations were dominated by hepatic artery thrombosis (54.3%) and recurrence of the underlying disease (45%). Perioperative mortality rate was 8.9% for first transplantations and 34.5% for retransplantations. Five-year patient and graft survival rate was 74.3% and 71%, respectively, after first transplantations and 54.7% and 52.9%, respectively, after retransplantations.
  
  
  CONCLUSIONS
  Development of liver transplantation program provided more than 1000 transplantations and excellent long-term results. Liver failure caused by hepatitis C and B infections remains the most common cause of liver transplantation and structure of other indications is consistent with European data.
authors: Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Poland.
authors: Marek
authors: M
authors: Krawczyk
authors: Michał
authors: M
authors: Grąt
authors: Krzysztof
authors: K
authors: Barski
authors: Joanna
authors: J
authors: Ligocka
authors: Arkadiusz
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authors: Antczak
authors: Oskar
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authors: Kornasiewicz
authors: Michał
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authors: Skalski
authors: Waldemar
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authors: Nyckowski
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authors: Zieniewicz
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authors: Grzelak
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authors: Pawlak
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authors: Wróblewski
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authors: Paluszkiewicz
authors: Bogusław
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authors: Najnigier
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authors: Dudek
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authors: Remiszewski
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authors: Smoter
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authors: Grodzicki
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authors: Korba
authors: Marcin
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authors: Kotulski
authors: Bartosz
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authors: Cieślak
authors: Piotr
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authors: Kalinowski
authors: Piotr
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authors: Gierej
authors: Mariusz
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authors: Frączek
authors: Łukasz
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authors: Rdzanek
authors: Rafał
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authors: Stankiewicz
authors: Konrad
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authors: Kobryń
authors: Łukasz
authors: Ł
authors: Nazarewski
authors: Dorota
authors: D
authors: Leonowicz
authors: Magdalena
authors: M
authors: Urban-Lechowicz
authors: Anna
authors: A
authors: Skwarek
authors: Dorota
authors: D
authors: Giercuszkiewicz
authors: Agata
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authors: Paczkowska
authors: Jolanta
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authors: Piwowarska
authors: Remigiusz
authors: R
authors: Gelo
authors: Paweł
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authors: Andruszkiewicz
authors: Anna
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authors: Brudkowska
authors: Renata
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authors: Andrzejewska
authors: Grzegorz
authors: G
authors: Niewiński
authors: Beata
authors: B
authors: Kilińska
authors: Aleksandra
authors: A
authors: Zarzycka
authors: Robert
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authors: Nowak
authors: Cezary
authors: C
authors: Kosiński
authors: Teresa
authors: T
authors: Korta
authors: Urszula
authors: U
authors: Ołdakowska-Jedynak
authors: Joanna
authors: J
authors: Sańko-Resmer
authors: Bartosz
authors: B
authors: Foroncewicz
authors: Jacek
authors: J
authors: Ziółkowski
authors: Krzysztof
authors: K
authors: Mucha
authors: Grzegorz
authors: G
authors: Senatorski
authors: Leszek
authors: L
authors: Pączek
authors: Andrzej
authors: A
authors: Habior
authors: Robert
authors: R
authors: Lechowicz
authors: Sławomir
authors: S
authors: Polański
authors: Elżbieta
authors: E
authors: Leowska
authors: Ryszard
authors: R
authors: Pacho
authors: Małgorzata
authors: M
authors: Andrzejewska
authors: Olgierd
authors: O
authors: Rowiński
authors: Sławomir
authors: S
authors: Kozieł
authors: Jerzy
authors: J
authors: Żurakowski
authors: Bogna
authors: B
authors: Ziarkiewicz-Wróblewska
authors: Barbara
authors: B
authors: Górnicka
authors: Piotr
authors: P
authors: Hevelke
authors: Bogdan
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authors: Michałowicz
authors: Andrzej
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authors: Karwowski
authors: Jerzy
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authors: Szczerbań
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006085:Graft Survival; D006505:Hepatitis / Q000453:epidemiology / Q000601:surgery*; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D008103:Liver Cirrhosis / Q000453:epidemiology / Q000601:surgery*; D008113:Liver Neoplasms / Q000453:epidemiology / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods / Q000401:mortality / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D012008:Recurrence; D012086:Reoperation; D012189:Retrospective Studies; D018570:Risk Assessment; D016019:Survival Analysis; D055815:Young Adult