title: Resistance (weight lifting) training in an adolescent with McArdle disease.
abstract: Owing to the risk of severe rhabdomyolysis, clinicians advise McArdle disease patients to refrain from strenuous exercise, particularly weight lifting. A 15-year-old male McArdle disease patient performed a 6-week, supervised, light- to moderate-intensity (~65-70% of one-repetition-maximum) resistance (weight lifting) training program (2 sessions/week). Training resulted in ~27% and ~6% increase in one-repetition-maximum bench press and multipower squat performance while inducing no myoglobinuria. The patient changed to a lower disease severity class, that is, he became virtually asymptomatic in terms of exercise limitations. The authors' preliminary data suggest that supervised, light to moderate resistance training is feasible in children with McArdle disease and has potential clinical benefits.
authors: European University of Madrid, Madrid, Spain.
authors: Sergio
authors: S
authors: García-Benítez
authors: Steven J
authors: SJ
authors: Fleck
authors: Fernando
authors: F
authors: Naclerio
authors: Miguel Angel
authors: MA
authors: Martín
authors: Alejandro
authors: A
authors: Lucia
mesh_terms: D000293:Adolescent; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D019587:Dietary Supplements; D005240:Feasibility Studies; D005838:Genotype; D006012:Glycogen Storage Disease Type V / Q000175:diagnosis / Q000235:genetics / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D055070:Resistance Training; D013030:Spain; D016896:Treatment Outcome
chemical_list: D004040:Dietary Carbohydrates