title: Synthesis, isolation, characterization, and reactivity of high-energy stereogenic-at-Ru carbenes: stereochemical inversion through olefin metathesis and other pathways.
abstract: The synthesis, isolation, purification (routine silica gel chromatography), and spectroscopic characterization of high-energy endo stereogenic-at-Ru complex isomers, generated by ring-opening/cross-metathesis (ROCM) reaction of the corresponding exo carbenes, are disclosed. We provide experimental evidence showing that an endo isomer can undergo thermal or Brønsted acid-catalyzed polytopal rearrangement, causing conversion to the energetically favored exo carbene.
authors: Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, United States.
authors: R Kashif M
authors: RK
authors: Khan
authors: Adil R
authors: AR
authors: Zhugralin
authors: Sebastian
authors: S
authors: Torker
authors: Robert V
authors: RV
authors: O'Brien
authors: Pamela J
authors: PJ
authors: Lombardi
authors: Amir H
authors: AH
authors: Hoveyda