title: Choreito, a formula from Japanese traditional medicine (Kampo medicine), for massive hemorrhagic cystitis and clot retention in a pediatric patient with refractory acute lymphoblastic leukemia.
abstract: Hemorrhagic cystitis is critical in patients with hemato-oncological disorders. Unlike adult patients, there are limited modalities and invasive procedures are often not well tolerated in children with poor general conditions. We report a pediatric patient with refractory acute lymphoblastic leukemia who developed life-threatening massive gross hematuria. Along with platelet infusion every other day due to suppressed hematopoiesis, his gross hematuria and clot retention in the bladder were successfully treated with choreito, a formula from Japanese traditional medicine (Kampo medicine). He survived free from hematuria for more than four months. Choreito was well tolerated, and no adverse effects were observed throughout the course.
authors: Division of Hematology/Oncology, Children's Medical Center, Japanese Red Cross Nagoya First Hospital, Nagoya, Japan. kwnozomu@med.nagoya-u.ac.jp
authors: Nozomu
authors: N
authors: Kawashima
authors: Teykia E
authors: TE
authors: Deveaux
authors: Nao
authors: N
authors: Yoshida
authors: Kimikazu
authors: K
authors: Matsumoto
authors: Koji
authors: K
authors: Kato
mesh_terms: D002648:Child; D003556:Cystitis / Q000188:drug therapy* / Q000209:etiology; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use*; D006417:Hematuria / Q000188:drug therapy / Q000209:etiology; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008297:Male; D020835:Medicine, Kampo; D008517:Phytotherapy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy*; D013927:Thrombosis / Q000188:drug therapy* / Q000209:etiology; D001743:Urinary Bladder / Q000187:drug effects* / Q000473:pathology
chemical_list: D004365:Drugs, Chinese Herbal; C041804:choreito