title: Two cases of giant cell hepatitis in HIV-infected patients.
abstract: Giant cell hepatitis (GCH) has been rarely described in adult HIV patients, and its outcome remain unknown. We report two cases of GCH among 81 HIV patients co-infected with the hepatitis C virus (HCV). Both patients had a sustained virological response, suppression of HCV viral load and HIV viral suppression after highly active antiretroviral therapy. Our findings would suggest that the presence of giant cells does not influence the clinical course of hepatitis.
authors: Laboratory of Electron Microscopy, INMI-IRCCS ‘L Spallanzani’, Rome, Italy. falasca@inmi.i
authors: L
authors: L
authors: Falasca
authors: F
authors: F
authors: Del Nonno
authors: F
authors: F
authors: Palmieri
authors: R
authors: R
authors: Licordari
authors: G
authors: G
authors: Iannicelli
authors: G
authors: G
authors: Antonucci
authors: A
authors: A
authors: Baiocchini
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D000998:Antiviral Agents / Q000627:therapeutic use; D015726:Giant Cells / Q000473:pathology* / Q000821:virology*; D015658:HIV Infections / Q000188:drug therapy / Q000473:pathology* / Q000821:virology*; D006526:Hepatitis C / Q000188:drug therapy / Q000473:pathology* / Q000821:virology*; D006651:Histocytochemistry; D006801:Humans; D008099:Liver / Q000737:chemistry / Q000166:cytology / Q000821:virology; D008297:Male; D008875:Middle Aged; D019562:Viral Load
chemical_list: D000998:Antiviral Agents