title: [Current status and influencing factors regarding quality of life among patients with Alzheimer's disease].
abstract: OBJECTIVE
  To investigate the current status and influencing factors regarding quality of life among patients with Alzheimer's disease (AD).
  
  
  METHODS
  Through stratified cluster sampling method, two hundred patients with AD and their caregivers were chosen and interviewed. AD patients were assessed by questionnaires, Montreal Cognitive Assessment, and Quality of Life-Alzheimer's Disease (QOL-AD), in order to compare the reports from patients and caregivers on QOL-AD and to analyze related influencing factors. Descriptive analysis, paired t-test, analysis of variance (ANOVA), Pearson's correlation and multiple linear regression were performed using the Statistical Package for Social Science (SPSS).
  
  
  RESULTS
  The scores of reports from patients (28.78 ± 4.30) were lower than that from the caregivers' (30.05 ± 6.05). The difference was statistically significant (t = 2.122, P < 0.05) and was positively correlated (r = 0.312, P < 0.001). Data from multivariate analysis showed that cognitive level (t = 3.465, P = 0.001), marriage relationship (t = 3.062, P = 0.003), having public activities (t = 2.581, P = 0.011), personal characters (t = 2.254, P = 0.026), restricted diet pattern (t = 3.614, P < 0.001), regularly drinking tea (t = 2.652, P = 0.009) and doing housework (t = 3.180, P = 0.002) were predictive factors.
  
  
  CONCLUSIONS
  Scores from the caregiver's report on QOL-AD were higher than that from the patients'. Many factors influenced the quality of life on AD patients. Strategies on improving the quality of life among AD patients can be developed based on the findings of this study.
authors.affiliation: School of Public Health, Shanxi Medical University, Taiyuan 030001, China.
authors.forename: Min
authors.initials: M
authors.lastname: Xing
authors.forename: Yong-mei
authors.initials: YM
authors.lastname: Ai
authors.forename: Run-lian
authors.initials: RL
authors.lastname: He
authors.forename: Jian-wei
authors.initials: JW
authors.lastname: Gao
authors.forename: Ping-ping
authors.initials: PP
authors.lastname: Song
authors.forename: Xiao-cheng
authors.initials: XC
authors.lastname: Wang
authors.forename: Cai-hong
authors.initials: CH
authors.lastname: Gao
authors.forename: Hui-min
authors.initials: HM
authors.lastname: Zhang
authors.forename: Hong-mei
authors.initials: HM
authors.lastname: Yu
mesh_terms: D000544:Alzheimer Disease; D017028:Caregivers; D005260:Female; D006801:Humans; D008297:Male; D011788:Quality of Life; D011795:Surveys and Questionnaires