title: [Acute leukemia frequency observed in a reference hospital].
abstract: OBJECTIVE
  to compare the frequency of acute leukemia in two periods of study in a reference Hospital at Mexico City.
  
  
  METHODS
  it was an observational study. There were registered 250 cases with the morphology diagnostic criterion of acute leukemia.
  
  
  RESULTS
  63 cases versus 92 of acute lymphoid leukemia (ALL) and 16 versus 79 acute myeloid leukemia (AML) of 1990-1992 versus 2008-2009 respectively was observed; corresponding to 62 % in total of ALL in both periods and 38 % of AML. The ALL was the most frequent variant (62 % versus 38 %). The median age was 26 years, male 52 %. It showed a significant increase in the number of admissions in the period of 2008-2009 and acute promyelocytic leukemia also showed an increase (p = 0.001).
  
  
  CONCLUSIONS
  acute leukemia is the main cause of admission, mortality and morbidity. Our study differs slightly from the literature; the leukemia that diagnostic with major frequency was the acute lymphoid leukemia increasing his number in the period of 2008-2009. The significant rise due to an increase use of new diagnostic tools such as the flow cytometry and molecular biology.
authors.affiliation: Departamento de Hematología, Hospital General de México, Secretaría de Salud, Distrito Federal, México. wendy_gon@hotmail.com
authors.forename: Wendy Marlene
authors.initials: WM
authors.lastname: González-Salas
authors.forename: Irma
authors.initials: I
authors.lastname: Olarte-Carrillo
authors.forename: Mario
authors.initials: M
authors.lastname: Gutiérrez-Romero
authors.forename: Efreen Horacio
authors.initials: EH
authors.lastname: Montaño-Figueroa
authors.forename: Carlos
authors.initials: C
authors.lastname: Martínez-Murillo
authors.forename: Christian Omar
authors.initials: CO
authors.lastname: Ramos-Peñafiel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000453:epidemiology*; D012017:Referral and Consultation; D012189:Retrospective Studies; D055815:Young Adult