title: [Meta-analysis on the relationship between 25-hydroxyvitamin D level and hypertension].
abstract: OBJECTIVE
  To explore the association between 25-hydroxyvitamin D level and hypertension so as to provide rationales for developing preventive strategies and understanding the etiology of hypertension.
  
  
  METHODS
  The articles on the association of 25-hydroxyvitamin D level and hypertension were retrieved by searching international and national databases from 2000 to 2011. The relationship between 25-hydroxyvitamin D level and hypertension was assessed by Meta-analysis with Stata11.0 software.
  
  
  RESULTS
  The results of Meta analysis showed that the pooled OR values of hypertension with 25-hydroxyvitamin D level deficiency and sufficiency was 1.37 (95%CI 1.23 - 1.53). Subgroup analysis revealed in 25-hydroxyvitamin D level, can be drawn between 25-hydroxyvitamin D level and the incidence of hypertension was statistically significant. The pooled OR values of hypertension with 25-hydroxyvitamin D level in 35 nmol/L and 35 - 68 nmol/L were 2.02 (95%CI 1.49 - 2.74) and 1.23 (95%CI 1.02 - 1.49) (P < 0.05).
  
  
  CONCLUSIONS
  The 25-hydroxyvitamin D level is associated with hypertension. With regards to the question of whether or not the 25-hydroxyvitamin D level deficiency serves as one of the potential risk factor for hypertension, prospective studies of larger sample sizes are warranted.
authors.affiliation: Department of Clinical Epidemiology, First Affiliated Hospital, China Medical University, Shenyang 110001, China.
authors.forename: Yi-Ting
authors.initials: YT
authors.lastname: Liu
authors.forename: Yun-Fei
authors.initials: YF
authors.lastname: Cai
authors.forename: Jing-Pu
authors.initials: JP
authors.lastname: Shi
mesh_terms: D003430:Cross-Sectional Studies; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000453:epidemiology*; D012307:Risk Factors; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications*
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D