title: Cognitive deficits in patients with brain tumor.
abstract: OBJECTIVE
  To discuss the present status and progress of clinical research on the cognitive effects caused by different types of brain tumors and common treatments.
  
  
  METHODS
  The data used in this review were mainly from PubMed articles published in English from 1990 to Febuary 2012. Research terms were "cognitive deficits" or "cognitive dysfunction".
  
  
  METHODS
  Articals including any information about brain tumor related cognitive deficits were selected.
  
  
  RESULTS
  It is widely accepted that brain tumors and related treatments can impair cognitive function across many domains, and can impact on patients' quality of life. Tumor localization, lateralization, surgery, drugs, radiotherapy and chemotherapy are all thought to be important factors in this process. However, some conflicting findings regarding brain tumor-related cognitive deficits have been reported. It can be difficult to determine the mechanism of these treatments, such as chemotherapy, antibiotics, antiepileptics, and steroids. Future research is needed to clarify these potential treatment effects.
  
  
  CONCLUSIONS
  Cognitive function is important for patients with brain tumor. Much more focus has been paid on this field. It should be regarded as an important prognostic index for the patients with brain tumor, and neuropsychological tests should be used in regular examinations.
authors.affiliation: Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Shen
authors.forename: Wei-Min
authors.initials: WM
authors.lastname: Bao
authors.forename: Bo-Jie
authors.initials: BJ
authors.lastname: Yang
authors.forename: Rong
authors.initials: R
authors.lastname: Xie
authors.forename: Xiao-Yun
authors.initials: XY
authors.lastname: Cao
authors.forename: Shi-Hai
authors.initials: SH
authors.lastname: Luan
authors.forename: Ying
authors.initials: Y
authors.lastname: Mao
mesh_terms: D001932:Brain Neoplasms / Q000503:physiopathology*; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000503:physiopathology*; D005910:Glioma / Q000503:physiopathology; D006801:Humans