title: Impact of a rural village women (Asha) intervention on adherence to antiretroviral therapy in southern India.
abstract: BACKGROUND
  Despite the increased prevalence of HIV in the rural female population of India, adherence to antiretroviral therapy continues to be low because of several barriers that discourage rural women.
  
  
  OBJECTIVE
  This study aims to assess the effectiveness of an intervention (Asha-Life) delivered by Accredited Social Health Activists (Asha) to improve antiretroviral therapy adherence of rural women living with AIDS in India compared with that of a usual care group.
  
  
  METHODS
  Sixty-eight rural women living with AIDS, aged 18-45 years, participated in a prospective, randomized pilot clinical trial and were assessed for several factors affecting adherence, such as sociodemographic characteristics, health history, CD4 cell count, enacted stigma, depressive symptomology, help getting antiretroviral therapy, and perceived therapy benefits.
  
  
  RESULTS
  Findings at 6 months revealed that, although both groups improved their adherence to antiretroviral therapy, there was greater improvement in the Asha-Life group (p < .001), who reported a greater reduction in barriers to antiretroviral therapy than those in the usual care group.
  
  
  CONCLUSIONS
  Antiretroviral therapy adherence showed significant increase in the Asha-Life cohort in which basic education on HIV/AIDS, counseling on antiretroviral therapy, support from Ashas, financial assistance, and better nutrition, was provided. The Asha-Life intervention may have great potential in improving antiretroviral therapy adherence and decreasing barriers among rural women living with AIDS in India.
authors.affiliation: School of Nursing, University of California at Los Angeles, USA. anyamath@sonnet.ucla.edu
authors.forename: Adeline
authors.initials: A
authors.lastname: Nyamathi
authors.forename: Alecia Y
authors.initials: AY
authors.lastname: Hanson
authors.forename: Benissa E
authors.initials: BE
authors.lastname: Salem
authors.forename: Sanjeev
authors.initials: S
authors.lastname: Sinha
authors.forename: Kalyan K
authors.initials: KK
authors.lastname: Ganguly
authors.forename: Barbara
authors.initials: B
authors.lastname: Leake
authors.forename: Kartik
authors.initials: K
authors.lastname: Yadav
authors.forename: Mary
authors.initials: M
authors.lastname: Marfisee
mesh_terms: D000293:Adolescent; D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000188:drug therapy*; D006293:Health Promotion / Q000379:methods*; D006801:Humans; D007194:India; D008875:Middle Aged; D010865:Pilot Projects; D011446:Prospective Studies; D012424:Rural Population; D055815:Young Adult; D016903:Drug Monitoring
chemical_list: D044966:Anti-Retroviral Agents