title: Cycloaddition reaction of 2-vinylazetidines with benzyne: a facile access to 1-benzazocine derivatives.
abstract: The cycloaddition reaction of 2-vinylazetidines with benzyne proceeded smoothly without a catalyst, and various benzazocine derivatives were isolated in good to high yields. The scope of the reaction, as well as the reactions of other arynes, has been studied.
authors.affiliation: Department of Chemistry, Faculty of Science, Tokyo University of Science, Kagurazaka, Shinjuku, Tokyo, 162-8601, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Aoki
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Koya
authors.forename: Ryu
authors.initials: R
authors.lastname: Yamasaki
authors.forename: Shinichi
authors.initials: S
authors.lastname: Saito
mesh_terms: D001384:Azetidines / Q000737:chemistry*; D001392:Azocines / Q000138:chemical synthesis* / Q000737:chemistry; D001555:Benzene Derivatives / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D061565:Cycloaddition Reaction; D015394:Molecular Structure; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D001384:Azetidines; D001392:Azocines; D001555:Benzene Derivatives; D014753:Vinyl Compounds; C524146:benzyne