title: [Rapid frozen sections in neuropathology].
abstract: Neuropathological evaluation of frozen sections requires a) special expertise in neuropathological specimen assessment and neurooncology as well as b) a trustful and open communication culture with the neurosurgeons. In addition to frozen sections, cytological examinations of smear and touch preparations as supporting methods are available to reach a correct diagnosis: these additional methods should therefore be performed whenever possible. Besides evaluation of biopsy specimens, appraisal of resection specimens and resection margin controls are of high clinical relevance. In the case of diffusely infiltrating central nervous system (CNS) neoplasms, in particular gliomas, resection margin control is often not feasible in contrast to other types of solid tumor.
authors.affiliation: Abteilung für Neuropathologie, Institut für Pathologie, Medizinische Universität Graz, Auenbruggerplatz 25, 8036, Graz, Österreich. johannes.haybaeck@medunigraz.at
authors.forename: J
authors.initials: J
authors.lastname: Haybaeck
authors.forename: G
authors.initials: G
authors.lastname: von Campe
authors.forename: J A
authors.initials: JA
authors.lastname: Hainfellner
mesh_terms: D000622:Aminolevulinic Acid; D001706:Biopsy / Q000295:instrumentation*; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000473:pathology* / Q000601:surgery*; D005629:Frozen Sections / Q000295:instrumentation*; D006801:Humans; D053783:Magnetic Resonance Imaging, Interventional / Q000295:instrumentation; D011237:Predictive Value of Tests; D013116:Spinal Cord / Q000473:pathology; D013120:Spinal Cord Neoplasms / Q000473:pathology* / Q000601:surgery*; D013238:Stereotaxic Techniques / Q000295:instrumentation
chemical_list: D000622:Aminolevulinic Acid