title: Role of transcription at centromeres in budding yeast.
abstract: Centromeres are specialized chromosomal loci that are essential for proper chromosome segregation. Recent data show that a certain level of active transcription, regulated by transcription factors Cbf1 and Ste12, makes a direct contribution to centromere function in Saccharomyces cerevisiae. Here, we discuss the requirement and function of transcription at centromeres.
authors.affiliation: Nationwide Children's Hospital, Columbus, OH, USA.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Ohkuni
authors.forename: Katsumi
authors.initials: K
authors.lastname: Kitagawa
mesh_terms: D002503:Centromere / Q000235:genetics*; D015966:Gene Expression Regulation, Fungal; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism; D004718:Saccharomycetales / Q000235:genetics* / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism; D014158:Transcription, Genetic / Q000502:physiology*
chemical_list: D014157:Transcription Factors