title: Two cases of Wernicke's encephalopathy in young age patients receiving allogeneic hematopoietic stem cell transplantation.
abstract: Wernicke's encephalopathy is an acute neurolopsychiatric syndrome caused by thiamine deficiency, and classically presents with the triad of opthalmopathy, ataxia and altered mentality. Both prolonged total parenteral nutrition and reduced oral intake can induce Wernicke's encephalopathy during hematopoietic stem cell transplantation (HSCT). Although early treatment is important for recovery from Wernicke's encephalopathy, the vague symptoms and characteristics hinder early diagnosis. Furthermore, Wernicke's encephalopathy is not infrequent and can develop at any age during HSCT. Herein, we present two young patients developing Wernicke's encephalopathy during HSCT.
authors.affiliation: Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jung Woo
authors.initials: JW
authors.lastname: Han
authors.forename: Seungtaek
authors.initials: S
authors.lastname: Lim
authors.forename: Hye Sun
authors.initials: HS
authors.lastname: Shin
authors.forename: Hee Jin
authors.initials: HJ
authors.lastname: Park
authors.forename: Won Jai
authors.initials: WJ
authors.lastname: Jung
authors.forename: Seung Yeon
authors.initials: SY
authors.lastname: Kwon
authors.forename: Chuhl Joo
authors.initials: CJ
authors.lastname: Lyu
mesh_terms: D002648:Child; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008297:Male; D013831:Thiamine / Q000627:therapeutic use; D014184:Transplantation, Homologous; D014899:Wernicke Encephalopathy / Q000188:drug therapy / Q000628:therapy*
chemical_list: D013831:Thiamine