title: Darwinian evolution and tiding clones in multiple myeloma.
abstract: In this issue of Blood, Keats et al,(1) Egan et al,(2) and Walker et al(3) provide a genome-wide snapshot of the clonal landscape in multiple myeloma(MM)illustrating the complexity of the evolutionary process and the dynamics of clonal evolution over time.
authors.affiliation: University of Calgary.
authors.forename: Nizar J
authors.initials: NJ
authors.lastname: Bahlis
mesh_terms: D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D002880:Chromosomes, Human, Pair 11; D002883:Chromosomes, Human, Pair 14; D002894:Chromosomes, Human, Pair 4; D060965:Clonal Evolution / Q000235:genetics*; D056915:DNA Copy Number Variations; D005260:Female; D005799:Genes, Dominant / Q000502:physiology*; D018740:Genetic Heterogeneity; D006801:Humans; D007952:Leukemia, Plasma Cell / Q000235:genetics*; D008297:Male; D009101:Multiple Myeloma / Q000235:genetics* / Q000473:pathology*; D017422:Sequence Analysis, DNA; D014178:Translocation, Genetic / Q000235:genetics*