title: mTOR signaling fades POMC neurons during aging.
abstract: Hypothalamic POMC neurons contribute to the regulation of energy homeostasis and glucose metabolism. In this issue of Neuron, Yang et al. (2012) show that the mTOR pathway has a pivotal role in deterioration of POMC neurons during age-dependent obesity.
authors.affiliation: Program in Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520, USA.
authors.forename: Jae Geun
authors.initials: JG
authors.lastname: Kim
authors.forename: Tamas L
authors.initials: TL
authors.lastname: Horvath