title: Multimodality image fusion-guided procedures: technique, accuracy, and applications.
abstract: Personalized therapies play an increasingly critical role in cancer care: Image guidance with multimodality image fusion facilitates the targeting of specific tissue for tissue characterization and plays a role in drug discovery and optimization of tailored therapies. Positron-emission tomography (PET), magnetic resonance imaging (MRI), and contrast-enhanced computed tomography (CT) may offer additional information not otherwise available to the operator during minimally invasive image-guided procedures, such as biopsy and ablation. With use of multimodality image fusion for image-guided interventions, navigation with advanced modalities does not require the physical presence of the PET, MRI, or CT imaging system. Several commercially available methods of image-fusion and device navigation are reviewed along with an explanation of common tracking hardware and software. An overview of current clinical applications for multimodality navigation is provided.
authors.affiliation: Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, USA. naj@mail.nih.gov
authors.forename: Nadine
authors.initials: N
authors.lastname: Abi-Jaoudeh
authors.forename: Jochen
authors.initials: J
authors.lastname: Kruecker
authors.forename: Samuel
authors.initials: S
authors.lastname: Kadoury
authors.forename: Hicham
authors.initials: H
authors.lastname: Kobeiter
authors.forename: Aradhana M
authors.initials: AM
authors.lastname: Venkatesan
authors.forename: Elliot
authors.initials: E
authors.lastname: Levy
authors.forename: Bradford J
authors.initials: BJ
authors.lastname: Wood
mesh_terms: D001706:Biopsy / Q000379:methods; D055590:Electromagnetic Phenomena; D057510:Endovascular Procedures; D057918:Fiducial Markers; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional; D053783:Magnetic Resonance Imaging, Interventional; D009369:Neoplasms / Q000628:therapy*; D049268:Positron-Emission Tomography; D057285:Precision Medicine; D015641:Radiography, Interventional; D014057:Tomography, X-Ray Computed