title: Curbing the opioid epidemic in the United States: the risk evaluation and mitigation strategy (REMS).
authors.affiliation: Department of Emergency Medicine, New York University School of Medicine, 455 First Ave, Room 123, New York, NY 10016, USA. lewis.nelson@nyumc.org
authors.forename: Lewis S
authors.initials: LS
authors.lastname: Nelson
authors.forename: Jeanmarie
authors.initials: J
authors.lastname: Perrone
mesh_terms: D000701:Analgesics, Opioid / Q000009:adverse effects* / Q000506:poisoning; D062787:Drug Overdose / Q000453:epidemiology; D004335:Drug and Narcotic Control / Q000331:legislation & jurisprudence* / Q000379:methods; D058872:Epidemics; D033161:Government Regulation; D006801:Humans; D056687:Off-Label Use; D009293:Opioid-Related Disorders / Q000453:epidemiology* / Q000517:prevention & control*; D010146:Pain / Q000188:drug therapy; D005791:Patient Care / Q000592:standards; D010818:Practice Patterns, Physicians'; D011358:Product Surveillance, Postmarketing; D018570:Risk Assessment; D014481:United States / Q000453:epidemiology; D014486:United States Food and Drug Administration / Q000331:legislation & jurisprudence
chemical_list: D000701:Analgesics, Opioid