title: Reactive histiocytosis of the orbit and posterior segment in a dog.
abstract: We present a case of reactive histiocytic disease involving the orbit, optic nerve, retina, and choroid in a Border Collie dog initially presenting for vision loss. Long-term partial return of vision has been achieved with systemic immunosuppression. Anterior segment and ocular surface manifestations of reactive histiocytic disease in dogs are relatively common. Posterior segment and orbital involvement, however, are minimally documented in the existing literature. To the authors' knowledge, this is the first report of disease confined to the orbit and posterior segment as well as the first report of vision loss as a presenting complaint for reactive histiocytic disease. Clinical, magnetic resonance imaging, cytologic, and histopathologic findings are reviewed.
authors.affiliation: Tufts Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA. stephanie.pumphrey@tufts.edu
authors.forename: Stephanie A
authors.initials: SA
authors.lastname: Pumphrey
authors.forename: Stefano
authors.initials: S
authors.lastname: Pizzirani
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Pirie
authors.forename: Amy F
authors.initials: AF
authors.lastname: Sato
authors.forename: Faith I
authors.initials: FI
authors.lastname: Buckley
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D004283:Dog Diseases / Q000188:drug therapy / Q000473:pathology*; D004285:Dogs; D005128:Eye Diseases / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D015614:Histiocytosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D008297:Male; D011241:Prednisone / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D011241:Prednisone