title: Proteomics of the rodent malaria parasite using matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight tandem mass spectrometry.
abstract: Plasmodium berghei strain NK65 is a rodent malaria parasite species widely used as a model of the human-infectious malaria parasite.  Because a rodent malaria parasite model allows issues to be addressed which would not be possible with human-infectious species, e.g., mode of action and in vivo screening, a convenient method to analyze the malaria parasite proteome is required.  The proteins of P. berghei separated using two-dimensional polyacrylamide gel electrophoresis were analyzed using matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight tandem mass spectrometry.
authors.affiliation: Central Research Laboratory, Faculty of Pharmaceutical Sciences, Hoshi University, Shinagawa, Tokyo, Japan. kasai@hoshi.ac.jp
authors.forename: Hiroko F
authors.initials: HF
authors.lastname: Kasai
authors.forename: Mayumi
authors.initials: M
authors.lastname: Ikegami-Kawai
mesh_terms: D000818:Animals; D005260:Female; D051379:Mice; D008813:Mice, Inbred ICR; D010962:Plasmodium berghei / Q000737:chemistry*; D040901:Proteomics; D015800:Protozoan Proteins / Q000032:analysis*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013997:Time Factors
chemical_list: D015800:Protozoan Proteins