title: Surgical considerations about amyloid goiter.
abstract: Amyloidosis is an uncommon syndrome consisting of a number of disorders having in common an extracellular deposit of fibrillary proteins. This results in functional and structural changes in the affected organs, depending on deposit location and severity. Amyloid infiltration of the thyroid gland may occur in 50% and up to 80% of patients with primary and secondary amyloidosis respectively. Amyloid goiter (AG) is a true rarity, usually found associated to secondary amyloidosis. AG may require surgical excision, usually because of compressive symptoms. We report the case of a patient with a big AG occurring in the course of a secondary amyloidosis associated to polyarticular onset juvenile idiopathic arthritis who underwent total thyroidectomy. Current literature is reviewed, an attempt is made to provide action guidelines, and some surgical considerations on this rare condition are given.
authors.affiliation: Unidad de Cirugía General y Digestiva, Hospital Universitario Ramón y Cajal, Madrid, Spain. garciavillanueva@gmail.com
authors.forename: Augusto
authors.initials: A
authors.lastname: García Villanueva
authors.forename: María Jesús
authors.initials: MJ
authors.lastname: García Villanueva
authors.forename: Mercedes
authors.initials: M
authors.lastname: García Villanueva
authors.forename: Roberto
authors.initials: R
authors.lastname: Rojo Blanco
authors.forename: María Vicenta
authors.initials: MV
authors.lastname: Collado Guirao
authors.forename: Jacobo
authors.initials: J
authors.lastname: Cabañas Montero
authors.forename: Rafael
authors.initials: R
authors.lastname: Beni Pérez
authors.forename: Irene
authors.initials: I
authors.lastname: Moreno Montes
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000150:complications / Q000601:surgery*; D006042:Goiter / Q000150:complications / Q000601:surgery*; D006801:Humans; D008297:Male