title: Anesthetic considerations for rapid-onset obesity, hypoventilation, hypothalamic dysfunction, and autonomic dysfunction (ROHHAD) syndrome in children.
abstract: Rapid-onset obesity, hypoventilation, hypothalamic dysfunction, and autonomic dysfunction is an increasingly common diagnosis in patients who are being seen at tertiary care children's hospitals. We present two cases of anesthetics from the authors' own experience in addition to a comprehensive review of the disorder and anesthetic implications.
authors.affiliation: Department of Anesthesiology & Pediatrics, Stony Brook University Medical Center, Stony Brook Children's Hospital, Stony Brook, NY, USA. arvind.chandrakantan@stonybrookmedicine.edu
authors.forename: Arvind
authors.initials: A
authors.lastname: Chandrakantan
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Poulton
mesh_terms: D000759:Adjuvants, Anesthesia; D000700:Analgesics; D000732:Androstanols; D000768:Anesthesia, General / Q000379:methods*; D018685:Anesthetics, Inhalation; D001285:Atropine; D020211:Autonomic Dysreflexia / Q000150:complications* / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D003113:Colonoscopy; D020927:Dexmedetomidine; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives; D007027:Hypothalamic Diseases / Q000150:complications* / Q000601:surgery; D007040:Hypoventilation / Q000150:complications* / Q000601:surgery; D007440:Intubation; D007649:Ketamine; D008738:Methyl Ethers; D009467:Neuromuscular Depolarizing Agents; D009765:Obesity / Q000150:complications* / Q000601:surgery; D000077123:Rocuronium; D000077149:Sevoflurane; D013577:Syndrome; D014139:Tracheostomy
chemical_list: D000759:Adjuvants, Anesthesia; D000700:Analgesics; D000732:Androstanols; D018685:Anesthetics, Inhalation; D006993:Hypnotics and Sedatives; D008738:Methyl Ethers; D009467:Neuromuscular Depolarizing Agents; D000077149:Sevoflurane; D020927:Dexmedetomidine; D007649:Ketamine; D001285:Atropine; D000077123:Rocuronium