title: Acute gouty arthritis as a manifestation of immune reconstitution inflammatory syndrome after initiation of antiretroviral therapy.
abstract: Immune reconstitution inflammatory syndrome (IRIS) in HIV-infected subjects initiating antiretroviral therapy most commonly involves new or worsening manifestations of previously subclinical or overt infectious diseases. Reports of non-infectious IRIS are much less common but represent important diagnostic and treatment challenges. We report on a 34-year-old HIV-infected male patient with no history of gout who developed acute gouty arthritis in a single joint one month after initiating highly active antiretroviral therapy.
authors.affiliation: Departamento de Medicina Geral, Hospital Universitário Gaffrée e Guinle, Universidade Federal do Estado do Rio de Janeiro, Rua Mariz e Barros 775, Rio de Janeiro, Brazil. walter-eyer@unirio.br
authors.forename: Walter de Araujo
authors.initials: Wde A
authors.lastname: Eyer-Silva
authors.forename: Maria Cecília da Fonseca
authors.initials: MC
authors.lastname: Salgado
authors.forename: Jorge Francisco da Cunha
authors.initials: JF
authors.lastname: Pinto
authors.forename: Fernando Raphael de Almeida
authors.initials: FR
authors.lastname: Ferry
authors.forename: Rogério
authors.initials: R
authors.lastname: Neves-Motta
authors.forename: Marcelo Costa Velho Mendes de
authors.initials: MC
authors.lastname: Azevedo
authors.forename: Carlos Alberto
authors.initials: CA
authors.lastname: Morais-de-Sá
mesh_terms: D000208:Acute Disease; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D015210:Arthritis, Gouty / Q000139:chemically induced*; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome; D008297:Male