title: Uniform broadband excitation of crystallites in rotating solids using interleaved sequences of delays alternating with nutation.
abstract: In solids that are spinning about the magic angle, trains of short pulses in the manner of Delays Alternating with Nutations for Tailored Excitation (DANTE) allow one to improve the efficiency of the excitation of magnetization compared to rectangular pulses. By interleaving N pulse trains with N>1, one obtains 'DANTE-N' sequences comprising N pulses per rotor period that extend over K rotor periods. Optimized interleaved DANTE schemes with N>1 are shorter than basic DANTE-1 sequences with N=1. Therefore, they are less affected by coherent or incoherent decays, thus leading to higher signal intensities than can be obtained with basic DANTE-1 or with rectangular pulses. Furthermore, the shorter length of DANTE-N with N>1 increases the width of the spikelets in the excitation profile, allowing one to cover the range of isotropic chemical shifts and second-order quadrupolar effects typical for side-chain and backbone amide (14)N sites in peptides at B(0)=18.8 T. In DANTE-N, spinning sidebands only appear at multiples of the spinning frequency ν(rot), as if the samples were rotating at Nν(rot). We show applications to direct detection of nitrogen-14 nuclei with spin I=1 subject to large quadrupole interactions, using fast magic angle spinning (typically ν(rot)≥60 kHz), backed up by simulations that provide insight into the properties of basic and interleaved DANTE sequences. When used for indirect detection, we show by numerical simulations that even basic DANTE-1 sequences can lead to a four-fold boost of efficiency compared to standard rectangular pulses.
authors.affiliation: Institut des Sciences et Ingénierie Chimiques (ISIC), Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland. ronika.vitzthum@epfl.ch
authors.forename: Veronika
authors.initials: V
authors.lastname: Vitzthum
authors.forename: Marc A
authors.initials: MA
authors.lastname: Caporini
authors.forename: Simone
authors.initials: S
authors.lastname: Ulzega
authors.forename: Julien
authors.initials: J
authors.lastname: Trébosc
authors.forename: Olivier
authors.initials: O
authors.lastname: Lafon
authors.forename: Jean-Paul
authors.initials: JP
authors.lastname: Amoureux
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Bodenhausen