title: Unusual Manifestation of Gastric Helicobacter pylori Infection.
abstract: Infection with Helicobacter pylori (HP) is common in many parts of the world. While most patients are asymptomatic, it causes peptic ulcer disease and malignancy in some of them. Other rare conditions have occasionally been reported in association with this infection. We report a case of hypertrophic gastropathy caused by HP in a 52-year-old asymptomatic patient. He was found to have marked enlargement of the gastric mucosal folds on radiological imaging and endoscopy. A gastric mucosal biopsy showed HP colonization associated with neutrophilic inflammation. After exclusion of neoplasia, other infections and infiltrative disorders, HP was thought to be the cause of the gastric fold hypertrophy. The patient responded well to HP eradication therapy, with normalization of the gastric mucosal folds. HP infection should be considered in the differential diagnosis of hypertrophic gastropathy and treated accordingly.
authors.affiliation: Division of Gastroenterology and Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan.
authors.forename: Amit K
authors.initials: AK
authors.lastname: Dutta
authors.forename: Toshimi
authors.initials: T
authors.lastname: Chiba
authors.forename: Yosuke
authors.initials: Y
authors.lastname: Toya
authors.forename: Tomomi
authors.initials: T
authors.lastname: Mizutani
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kasugai
authors.forename: Nozomi
authors.initials: N
authors.lastname: Matsuda
authors.forename: Sho
authors.initials: S
authors.lastname: Shibata
authors.forename: Yukito
authors.initials: Y
authors.lastname: Abiko
authors.forename: Risaburo
authors.initials: R
authors.lastname: Akasaka
authors.forename: Naoki
authors.initials: N
authors.lastname: Yokoyama
authors.forename: Shuhei
authors.initials: S
authors.lastname: Oana
authors.forename: Shigeru
authors.initials: S
authors.lastname: Hirota
authors.forename: Masaki
authors.initials: M
authors.lastname: Endo
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Uesugi
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Sugai
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Suzuki