title: Feeling of cold hands and feet is a highly heritable phenotype.
abstract: The prevalence of the feeling of cold hands and feet (FCHF) is high in the                    general population but the etiology of FCHF is largely unknown. The aim of the                    present study was to explore whether the FCHF is heritable. Eight hundred and                    ninety-four pairs of twins completed a question about FCHF. Tetrachoric                    correlations for FCHF were .58, .29, .67, .52, and .04 for monozygotic male,                    dizygotic male, monozygotic female, and dizygotic female twins, respectively.                    Model-fitting analyses suggested that in the best fitting model, additive                    genetic and nonshared environmental variance including measurement error were                    64% (95% CI: 55%-72%) and 36% (28%-45%), respectively. Sex differences in                    genetic and environmental influences were not significant.
authors.affiliation: Mokpo National University, South                 Korea.
authors.forename: Yoon-Mi
authors.initials: YM
authors.lastname: Hur
authors.forename: Jeong-Ho
authors.initials: JH
authors.lastname: Chae
authors.forename: Ki Wha
authors.initials: KW
authors.lastname: Chung
authors.forename: Jung Jin
authors.initials: JJ
authors.lastname: Kim
authors.forename: Hoe-Uk
authors.initials: HU
authors.lastname: Jeong
authors.forename: Jong Woo
authors.initials: JW
authors.lastname: Kim
authors.forename: Sung Yum
authors.initials: SY
authors.lastname: Seo
authors.forename: Kyung Soo
authors.initials: KS
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003080:Cold Temperature; D005260:Female; D005528:Foot; D006225:Hand; D006801:Humans; D008297:Male; D008957:Models, Genetic; D010465:Perception; D012737:Sex Factors; D011795:Surveys and Questionnaires