title: Cobalt-catalyzed ortho-arylation of aromatic imines with aryl chlorides.
abstract: An ortho-arylation reaction of aromatic imines with aryl chlorides has been achieved using a cobalt-N-heterocyclic carbene catalyst in combination with a neopentyl Grignard reagent. The reaction takes place at room temperature to afford biaryl products in moderate to good yields.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
authors.forename: Ke
authors.initials: K
authors.lastname: Gao
authors.forename: Pin-Sheng
authors.initials: PS
authors.lastname: Lee
authors.forename: Chong
authors.initials: C
authors.lastname: Long
authors.forename: Naohiko
authors.initials: N
authors.lastname: Yoshikai
mesh_terms: D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry*; D007097:Imines / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D006843:Hydrocarbons, Chlorinated; D007097:Imines; D003035:Cobalt