title: [Retrospective analysis of treatment for severe ovary hyperstimulation syndrome complicated by pleural effusion and ascites].
abstract: OBJECTIVE
  To investigate the effectiveness of treatment for severe ovary hyperstimulation syndrome (OHSS) complicated by pleural effusion and ascites after in vitro fertilization preembryo transfer (IVF-ET).
  
  
  METHODS
  One hundred and thirty-two patients with severe OHSS in our hospital (from January 2007 to December 2010) were retrospectively analyzed and the efficacy of three therapeutic methods was compared. Twenty-five patients in group I were treated with low-molecular dextran and albumin, 67 patients in group II were treated with 6% medium molecular-weight hydroxyethyl starch, and 40 patients in group III were treated with active aspiration of pleural effusion and ascites.
  
  
  RESULTS
  All three therapies improved the symptoms of OHSS and various blood biochemical parameters. The duration of hospitalization of group III [(7.4±4.5) d] was significantly less than those of group I [(21.4±9.2) d] or II [(15.6±6.7) d], and the cost of group III [(2656.2±1882.8) Yuan] was also significantly lower than that of group I or II [(11937.6±7989.8) and (5182.7±2991.7) Yuan, respectively].
  
  
  CONCLUSIONS
  Abdominal B ultrasonography-guided trans-abdominal wall aspiration of pleural effusion and ascites combined with blood volume maintenance is an effective and economical way to treat OHSS.
authors.affiliation: Institute of Reproduction and Stem Cell, Central South University, Changsha, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Gong
authors.forename: Hui
authors.initials: H
authors.lastname: Guo
authors.forename: Yan
authors.initials: Y
authors.lastname: Shen
authors.forename: Juan
authors.initials: J
authors.lastname: Li
authors.forename: Guangxiu
authors.initials: G
authors.lastname: Lu
authors.forename: Ge
authors.initials: G
authors.lastname: Lin
mesh_terms: D000328:Adult; D001201:Ascites / Q000209:etiology* / Q000628:therapy; D003911:Dextrans / Q000008:administration & dosage; D004322:Drainage; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage; D007262:Infusions, Intravenous; D016471:Ovarian Hyperstimulation Syndrome / Q000150:complications* / Q000628:therapy*; D010062:Ovulation Induction / Q000009:adverse effects; D010996:Pleural Effusion / Q000209:etiology* / Q000628:therapy; D012189:Retrospective Studies; D012709:Serum Albumin / Q000008:administration & dosage
chemical_list: D003911:Dextrans; D006895:Hydroxyethyl Starch Derivatives; D012709:Serum Albumin