title: Ulcerative necrobiosis lipoidica responsive to colchicine.
abstract: Necrobiosis lipoidica is an uncommon granulomatous disease of unknown aetiology. Few treatments have emerged with consistent efficacy and the ulcerated form of necrobiosis lipoidica can be particularly difficult to treat. A 56-year-old non-diabetic woman with chronic ulcerative necrobiosis lipoidica unresponsive to other therapies was commenced on colchicine treatment. Complete resolution of the ulcers was observed after 2 months' therapy with colchicine 500 µg twice daily.
authors.affiliation: Royal Hobart Hospital, Hobart Launceston General Hospital, Launceston, Tasmania 7000, Australia. ccschofield@hotmail.com
authors.forename: Clare
authors.initials: C
authors.lastname: Schofield
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Sladden
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D003078:Colchicine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009335:Necrobiosis Lipoidica / Q000150:complications / Q000188:drug therapy*; D012883:Skin Ulcer / Q000209:etiology
chemical_list: D000893:Anti-Inflammatory Agents; D003078:Colchicine