title: The chemostat with lateral gene transfer.
abstract: We investigate the standard chemostat model when lateral gene transfer is taken into account. We will show that when the different genotypes have growth rate functions that are sufficiently close to a common growth rate function, and when the yields of the genotypes are sufficiently close to a common value, then the population evolves to a globally stable steady state, at which all genotypes coexist. These results can explain why the antibiotic-resistant strains persist in the pathogen population.
authors.affiliation: Department of Mathematics, University of Florida, Gainesville, FL 32611-8105, USA. deleenhe@math.ufl.edu
authors.forename: Patrick
authors.initials: P
authors.lastname: De Leenheer
authors.forename: Jack
authors.initials: J
authors.lastname: Dockery
authors.forename: Tomas
authors.initials: T
authors.lastname: Gedeon
authors.forename: Sergei S
authors.initials: SS
authors.lastname: Pilyugin
mesh_terms: D004352:Drug Resistance, Microbial / Q000235:genetics; D022761:Gene Transfer, Horizontal / Q000235:genetics*; D008954:Models, Biological