title: [Manifestation of synovial lesions in osteoarthritis].
abstract: Osteoarthritis is a degenerative joint disease,with the characters of degradation of articular cartilage, the formation of the joint marginal osteophyte and synovium lesions. Previous studies have focused on the treatment of articular cartilage lesions. In recent years, new research in shows synovial inflammation plays an important role in OA. Synovium lesions and synovial inflammation-related factors induced the degradation and destruction of articular cartilage, and promoted the development of osteoarthritis. The role of synovial lesions in osteoarthritis is increasingly prominent, and the treatment for synovial lesions will become a new target. So this paper reviews the various manifestations of synovial in osteoarthritis.
authors.affiliation: Putuo Hospital Affiliated to Shanghai Traditional Chinese Medicine University, Shanghai 200062, China.
authors.forename: Peng-Fei
authors.initials: PF
authors.lastname: Song
authors.forename: Wei-Bing
authors.initials: WB
authors.lastname: Kan
authors.forename: Qin
authors.initials: Q
authors.lastname: Yuan
authors.forename: Jing
authors.initials: J
authors.lastname: Zhao
authors.forename: Dian-Hong
authors.initials: DH
authors.lastname: Xie
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Wang
mesh_terms: D006801:Humans; D010003:Osteoarthritis / Q000473:pathology*; D013583:Synovial Membrane / Q000473:pathology*