title: Autoinflammatory syndromes: fever is not always a sign of infection.
abstract: Autoinflammatory syndromes are a newly understood group of conditions characterized by recurrent episodes of fever, rash, and serositis. Generalists and specialists should know about and consider these syndromes in the differential diagnosis of recurrent fever. This article reviews the genetics, pathophysiology, clinical presentation, and treatment of several of these relatively recently discovered diseases.
authors.affiliation: Center for Pediatric Rheumatology and Immunology, Cleveland Clinic, Cleveland, OH 44195, USA. zefta@ccf.org
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Zeft
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Spalding
mesh_terms: D003078:Colchicine / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006074:Gout Suppressants / Q000627:therapeutic use; D056660:Hereditary Autoinflammatory Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008297:Male; D054078:Mevalonate Kinase Deficiency / Q000175:diagnosis / Q000473:pathology; D009154:Mutation; D011379:Prognosis; D011788:Quality of Life / Q000523:psychology; D012306:Risk; D013577:Syndrome; D050257:Tubulin Modulators / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D006074:Gout Suppressants; D050257:Tubulin Modulators; D003078:Colchicine