title: Large pericardial effusion induced by minoxidil.
abstract: A 53-year-old male admitted with increased shortness of breath. In the physical examination, he had dyspnea, tachycardia and tachypnea. An echocardiogram showed large pericardial effusion (PE) as well as significant pulmonary hypertension. He had been started recently on minoxidil for blood pressure control. PE was reported to occur with minoxidil treatment both in patients undergoing dialysis and those with normal renal function. Pulmonary hypertension has been reported to affect the cardiac tamponade physiology. Because of significant pulmonary hypertension in our patient, a right heart catheterization was also done, which prevented cardiac tamponade. He was treated conservatively without any intervention, and PE resolved spontaneously after discontinuation of minoxidil.
authors.affiliation: University of Pittsburgh Heart and Vascular Institute, Pittsburgh, USA. mcilingiroglu@yahoo.com
authors.forename: Mehmet
authors.initials: M
authors.lastname: Çilingiroğlu
authors.forename: Nuri
authors.initials: N
authors.lastname: Akkuş
authors.forename: Salil
authors.initials: S
authors.lastname: Sethi
authors.forename: Kalgi A
authors.initials: KA
authors.lastname: Modi
mesh_terms: D000959:Antihypertensive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004452:Echocardiography; D065627:Familial Primary Pulmonary Hypertension; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D008914:Minoxidil / Q000009:adverse effects* / Q000627:therapeutic use; D010490:Pericardial Effusion / Q000139:chemically induced* / Q000000981:diagnostic imaging
chemical_list: D000959:Antihypertensive Agents; D008914:Minoxidil