title: Erythropoietin May Improve Anemia in Patients with Autoimmune Hemolytic Anemia Associated with Reticulocytopenia.
abstract: BACKGROUND: Management of patients with autoimmune hemolytic anemia (AIHA) and reticulocytopenia remains challenging.  CASE REPORTS: Two patients with decompensated AIHA who were receiving immunosuppressive drugs were treated with erythropoietin (EPO). Administration of EPO increased reticulocyte counts and hemoglobin concentrations in both cases. One patient completely recovered following a short course of treatment. Hemolysis could be compensated in the second patient using only mild doses of immunosuppressive drugs in combination with EPO.  CONCLUSION: The administration of EPO should be considered in patients with therapy-refractory AIHA, particularly in the presence of reticulocytopenia.
authors.affiliation: Institute for Transfusion Medicine, Universitätsmedizin Charité - Universitätsmedizin Berlin, Germany.
authors.forename: Olga
authors.initials: O
authors.lastname: Arbach
authors.forename: Robert
authors.initials: R
authors.lastname: Funck
authors.forename: Frank
authors.initials: F
authors.lastname: Seibt
authors.forename: Abdulgabar
authors.initials: A
authors.lastname: Salama