title: [Alterations in pulmonary artery pressure following mitral valve replacement].
abstract: OBJECTIVE
  We sought to evaluate the early postoperative hemodynamics and clinical aspects in patients with moderate to severe pulmonary artery pressure (PAP) who underwent mitral valve replacement (MVR) due to isolated mitral valve stenosis.
  
  
  METHODS
  Fifty patients (33 women, 17 men; mean age 45.8±11.2) were divided into two groups according to mean PAP levels (PAP <50 mmHg as Group I and PAP >50 mmHg as Group II). PAP and pulmonary capillary wedge pressure (PCWP) values were recorded using Swan-Ganz catheter just before the surgery in the operation theatre. These measurements were repeated after weaning from cardiopulmonary bypass, at 1, 12 and 24 hours. Intubation period in the intensive care unit, need for inotropic agents in the pre-and postoperative course, and mortality and morbidity data were also evaluated. Transthoracic echocardiography was used to measure PAP at the postoperative 24th hour and at the 2nd month after the surgery.
  
  
  RESULTS
  Mean PAP decreased significantly in both groups compared with basal levels. The regression was higher in Group II than Group I. Decrease in PCWP was more significant in Group II. PAP had decreased similarly in both groups according to the postoperative 24th hour echocardiographic evaluation; however, at the postoperative second month follow-up, the decrease in PAP was more significant in Group II.
  
  
  CONCLUSIONS
  Pulmonary arterial and left atrial pressures significantly decreased in the early periods when the stenosis was alleviated in the isolated mitral stenosis cases with moderate or high PAP levels. This study demonstrates the increased morbidity in patients with higher PAP levels undergoing surgery. It seems that moderate PAP levels do not have a negative influence on postoperative outcomes.
authors.affiliation: Department of Cardiovascular Surgery, Türkiye Yüksek İhtisas Hospital, Ankara, Turkey.
authors.forename: Gökhan
authors.initials: G
authors.lastname: Lafçı
authors.forename: Adem Ilkay
authors.initials: AI
authors.lastname: Diken
authors.forename: Hikmet Selçuk
authors.initials: HS
authors.lastname: Gedik
authors.forename: Kemal
authors.initials: K
authors.lastname: Korkmaz
authors.forename: Fırat
authors.initials: F
authors.lastname: Özcan
authors.forename: İrfan
authors.initials: İ
authors.lastname: Taşoğlu
authors.forename: Garip
authors.initials: G
authors.lastname: Altıntaş
authors.forename: Kerim
authors.initials: K
authors.lastname: Çağlı
mesh_terms: D000328:Adult; D002315:Cardiopulmonary Bypass; D002407:Catheterization, Swan-Ganz; D004452:Echocardiography; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D006976:Hypertension, Pulmonary / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000503:physiopathology / Q000601:surgery*; D011184:Postoperative Period; D057234:Preoperative Period; D011669:Pulmonary Wedge Pressure / Q000502:physiology*