title: A novel approach for detection and classification of mammographic microcalcifications using wavelet analysis and extreme learning machine.
abstract: The objective of this paper is to reveal the effectiveness of wavelet based tissue texture analysis for microcalcification detection in digitized mammograms using Extreme Learning Machine (ELM). Microcalcifications are tiny deposits of calcium in the breast tissue which are potential indicators for early detection of breast cancer. The dense nature of the breast tissue and the poor contrast of the mammogram image prohibit the effectiveness in identifying microcalcifications. Hence, a new approach to discriminate the microcalcifications from the normal tissue is done using wavelet features and is compared with different feature vectors extracted using Gray Level Spatial Dependence Matrix (GLSDM) and Gabor filter based techniques. A total of 120 Region of Interests (ROIs) extracted from 55 mammogram images of mini-Mias database, including normal and microcalcification images are used in the current research. The network is trained with the above mentioned features and the results denote that ELM produces relatively better classification accuracy (94%) with a significant reduction in training time than the other artificial neural networks like Bayesnet classifier, Naivebayes classifier, and Support Vector Machine. ELM also avoids problems like local minima, improper learning rate, and over fitting.
authors.affiliation: Department of Biomedical Engineering, PSG College of Technology, Coimbatore, India. emalarpsg@gmail.com
authors.forename: E
authors.initials: E
authors.lastname: Malar
authors.forename: A
authors.initials: A
authors.lastname: Kandaswamy
authors.forename: D
authors.initials: D
authors.lastname: Chakravarthy
authors.forename: A
authors.initials: A
authors.lastname: Giri Dharan
mesh_terms: D000465:Algorithms; D001185:Artificial Intelligence; D001499:Bayes Theorem; D001941:Breast Diseases / Q000175:diagnosis* / Q000473:pathology; D002114:Calcinosis / Q000175:diagnosis* / Q000473:pathology; D016208:Databases, Factual; D005260:Female; D006801:Humans; D008327:Mammography / Q000379:methods*; D012372:ROC Curve; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D058067:Wavelet Analysis