title: Transcatheter aortic valve implantation 10-year anniversary: review of current evidence and clinical implications.
abstract: Surgical aortic valve replacement (SAVR) is currently the standard of care to treat patients with severe symptomatic aortic stenosis (AS) and is generally accepted to alleviate symptoms and prolong survival. Based on the results of randomized trials, transcatheter aortic valve implantation (TAVI) is the new standard of care for patients with symptomatic AS who are deemed 'inoperable'. Debatably, TAVI is also an alternative to SAVR in selected patients who are at high risk but operable. As we approach 10 years of clinical experience with TAVI, with over 50 000 implantations in 40 countries, a review of the current literature and clinical outcomes with this rapidly evolving technology is appropriate.
authors.affiliation: Columbia University Medical Center and the Cardiovascular Research Foundation, 161 Fort Washington Avenue, 6th Floor, New York, NY 10032, USA. pg2295@columbia.edu
authors.forename: Philippe
authors.initials: P
authors.lastname: Généreux
authors.forename: Stuart J
authors.initials: SJ
authors.lastname: Head
authors.forename: David A
authors.initials: DA
authors.lastname: Wood
authors.forename: Susheel K
authors.initials: SK
authors.lastname: Kodali
authors.forename: Mathew R
authors.initials: MR
authors.lastname: Williams
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Paradis
authors.forename: Marco
authors.initials: M
authors.lastname: Spaziano
authors.forename: A Pieter
authors.initials: AP
authors.lastname: Kappetein
authors.forename: John G
authors.initials: JG
authors.lastname: Webb
authors.forename: Alain
authors.initials: A
authors.lastname: Cribier
authors.forename: Martin B
authors.initials: MB
authors.lastname: Leon
mesh_terms: D001024:Aortic Valve Stenosis / Q000503:physiopathology / Q000628:therapy*; D006328:Cardiac Catheterization / Q000379:methods*; D003362:Cost-Benefit Analysis; D005240:Feasibility Studies; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D018579:Patient Selection; D011474:Prosthesis Design; D011475:Prosthesis Failure; D016032:Randomized Controlled Trials as Topic; D012042:Registries; D016896:Treatment Outcome