title: [Bisphosphonate related osteonecrosis of the jaws: a case report and review of the literature].
abstract: Bisphosphonate compounds are used to treat osteoporosis and malignant bone metastasis. Despite the benefits related to use of these medications, osteonecrosis of the jaws is a significant complication in a subset of patients receiving these drugs. This complication occurs either spontaneously or after a simple dento-alveolar surgery. Recently there was a patient who showed the features of bisphosphonate related osteonecrosis of the jaws (BRONJ) in our hospital. This article reported one typical case of osteonecrosis of the maxilla treated with Zoledronic acid and reviewed the relevant literature related to pathogenesis, clinical presentation as well as management and prevention of this new complication.
authors.affiliation: Dental Center, Fifth Affiliated Hospital, Wenzhou Medical College, Central Hospital of Lishui City, Lishui 323000, Zhejiang Province, China. ywcls@sina.com
authors.forename: Wen-cheng
authors.initials: WC
authors.lastname: Ye
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
mesh_terms: D059266:Bisphosphonate-Associated Osteonecrosis of the Jaw; D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D006801:Humans; D007093:Imidazoles; D007568:Jaw; D010020:Osteonecrosis; D000077211:Zoledronic Acid
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D007093:Imidazoles; D000077211:Zoledronic Acid