title: Cruciferous vegetables intake is inversely associated with risk of breast cancer: a meta-analysis.
abstract: OBJECTIVE
  The objective of the study was to examine the associations of cruciferous vegetables intake with risk of breast cancer.
  
  
  METHODS
  Studies were identified by searching PubMed databases and screening the references of retrieved articles and reviews. Summary odds ratios (ORs) for the highest versus lowest cruciferous vegetables consumption levels were calculated using fixed or random effects models depending on heterogeneity between studies. Heterogeneity among studies was examined using Q and I(2) statistics. Publication bias was assessed using the Egger's and Begg's tests.
  
  
  RESULTS
  Thirteen epidemiologic studies (11 case-control and 2 cohort studies) were included in the meta-analysis. The combined results from all studies indicated that high cruciferous vegetables intake was significantly associated with reduced breast cancer risk (RR = 0.85, 95% CI = 0.77-0.94).
  
  
  CONCLUSIONS
  Findings from this meta-analysis suggest that cruciferous vegetables consumption may reduce the risk of breast cancer. Because of the limited number of studies, further prospective studies are needed to explore the protective effect of cruciferous vegetables on breast cancer.
authors.affiliation: Department of Gastrointestinal Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Qingchun Road 79, Hangzhou, Zhejiang Province, China.
authors.forename: Xiaojiao
authors.initials: X
authors.lastname: Liu
authors.forename: Kezhen
authors.initials: K
authors.lastname: Lv
mesh_terms: D001937:Brassica; D001943:Breast Neoplasms / Q000453:epidemiology*; D016001:Confidence Intervals; D004032:Diet; D005260:Female; D006801:Humans; D016017:Odds Ratio; D012307:Risk Factors