title: Relationship of epidermal melanocytes and langerhans cells with epidermal cambial cells.
abstract: Studies of mouse ear epidermis showed that proliferative activity of basal epidermal cells has two active and two passive phases throughout 24 h. Active phases consist of two subphases: long (proliferation of cambial cell descendants) and very short (cambial cell proliferation). Cambial cells proliferate at the boundary between active and passive phases; this results in an increase in the counts of epidermal melanocytes and Langerhans cells resultant from division of epidermal cambial cells. The count of Langerhans cells almost 2-fold surpasses melanocyte count, because melanocytes gradually transform into epidermal basal cells.
authors.affiliation: NN Blokhin Russian Oncological Research Center, Russian Academy of Medical Sciences, Moscow, Russia. javisheva@rambler.ru
authors.forename: T M
authors.initials: TM
authors.lastname: Yavisheva
authors.forename: S D
authors.initials: SD
authors.lastname: Shcherbakov
authors.forename: I S
authors.initials: IS
authors.lastname: Golubeva
authors.forename: L A
authors.initials: LA
authors.lastname: Savluchinskaya
authors.forename: N I
authors.initials: NI
authors.lastname: Ryzhova
mesh_terms: D000818:Animals; D002455:Cell Division / Q000502:physiology; D049109:Cell Proliferation; D000078404:Epidermal Cells; D066298:In Vitro Techniques; D007801:Langerhans Cells / Q000166:cytology*; D008297:Male; D008544:Melanocytes / Q000166:cytology*; D051379:Mice