title: Respiratory distress of the newborn: congenital laryngeal atresia.
abstract: Congenital laryngeal atresia is a rare cause of respiratory distress of the newborn. The defect may be isolated or occur in association with other congenital abnormalities, notably the presence of a tracheoesophageal fistula, esophageal atresia, encephalocele, or Congenital High Airway Obstructive Syndrome (CHAOS). We present the case of a newborn with no identified intrapartum abnormalities with respiratory distress at birth secondary to near-complete laryngeal atresia. Management included tracheostomy, repeated endoscopic incisions, and serial balloon dilatations employing the topical use of Mitomycin C. Seven year follow-up was significant for mobilization of the true vocal cords bilaterally, as well as successful decannulation.
authors.affiliation: Department of Otolaryngology - Head & Neck Surgery, Naval Medical Center San Diego, CA 92134-2200, United States. Ambrosio@ucla.edu
authors.forename: Art
authors.initials: A
authors.lastname: Ambrosio
authors.forename: Anthony
authors.initials: A
authors.lastname: Magit
mesh_terms: D001999:Bronchoscopy; D004106:Dilatation; D005931:Glottis / Q000002:abnormalities; D006801:Humans; D007231:Infant, Newborn; D007442:Intubation, Intratracheal; D007818:Laryngeal Diseases / Q000151:congenital* / Q000628:therapy; D007828:Laryngoscopy; D007829:Laryngostenosis / Q000209:etiology / Q000628:therapy; D007830:Larynx / Q000002:abnormalities*; D008297:Male; D016685:Mitomycin / Q000627:therapeutic use; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology* / Q000628:therapy; D014139:Tracheostomy
chemical_list: D016685:Mitomycin