title: Hydrogen peroxide and glucose biosensor based on silver nanowires synthesized by polyol process.
abstract: Silver nanowires synthesized through a polyol process using polyvinylpyrrolidone as protection (PVP-AgNWs) were used as a new electrode material for constructing a sensor. Hydrogen peroxide (H(2)O(2)) and glucose were used as analytes to demonstrate the sensor performance of the PVP-AgNWs. It is found that the PVP-AgNWs-modified glassy carbon electrode (PVP-AgNWs/GCE) exhibits remarkable catalytic performance toward H(2)O(2) reduction. This sensor has a fast amperometric response time of less than 2 s and the catalytic current is linear over the concentration of H(2)O(2) ranging from 20 μM to 3.62 mM (R = 0.998) with a detection limit of 2.3 μM estimated on a signal-to-noise ratio of 3. A glucose biosensor was constructed by immobilizing glucose oxidase (GOD) onto the surface of the PVP-AgNWs/GCE. The resultant glucose biosensor can be used for glucose detection in human blood serum with a sensitivity of 15.86 μA mM(-1) cm(-2) and good selectivity and stability.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Science, China.
authors.forename: Xuejuan
authors.initials: X
authors.lastname: Yang
authors.forename: Jing
authors.initials: J
authors.lastname: Bai
authors.forename: Yinhu
authors.initials: Y
authors.lastname: Wang
authors.forename: Xiue
authors.initials: X
authors.lastname: Jiang
authors.forename: Xiaoying
authors.initials: X
authors.lastname: He
mesh_terms: D015374:Biosensing Techniques; D001786:Blood Glucose / Q000032:analysis*; D004566:Electrodes; D005947:Glucose / Q000032:analysis*; D005949:Glucose Oxidase / Q000737:chemistry*; D006801:Humans; D006861:Hydrogen Peroxide / Q000032:analysis* / Q000737:chemistry; D053768:Metal Nanoparticles; D053761:Nanocomposites; D053770:Nanowires; D011205:Povidone / Q000737:chemistry; D012834:Silver
chemical_list: D001786:Blood Glucose; D012834:Silver; D006861:Hydrogen Peroxide; D005949:Glucose Oxidase; D011205:Povidone; D005947:Glucose