title: [Acute tumor lysis syndrome in the setting of advanced gastric cancer].
abstract: A 69-year-old man was admitted with right flank pain. The patient was diagnosed with advanced gastric cancer with multiple metastases in the liver and abdominal lymph nodes and underwent chemotherapy. Three days following the initial administration of S-1 plus cisplatin, the patient developed tumor lysis syndrome (TLS) with increased LDH, hyperuricemia, hyperkalemia, and elevated creatinine. Although rare, TLS following chemotherapy for solid tumors is a potentially fatal complication, and high physician awareness is required, especially in patients with risk factors, such as bulky disease.
authors.affiliation: Department of Gastroenterology, National Hospital Oraganization Kure Medical Center, Japan.
authors.forename: Tomoki
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Toshio
authors.initials: T
authors.lastname: Kuwai
authors.forename: Sohei
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Haruki
authors.initials: H
authors.lastname: Kimura
authors.forename: Keiichi
authors.initials: K
authors.lastname: Masaki
authors.forename: Mayuko
authors.initials: M
authors.lastname: Hirata
authors.forename: Atsushi
authors.initials: A
authors.lastname: Yamaguchi
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Kouno
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kohno
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology*; D000368:Aged; D006801:Humans; D008297:Male; D013274:Stomach Neoplasms / Q000150:complications / Q000473:pathology*; D015275:Tumor Lysis Syndrome / Q000209:etiology*