title: [Histiocytic necrotizing lymphadenitis: (Kukuchi-Fujimoto disease): a diagnostic challenge].
abstract: Kikuchi-Fujimoto disease, also called Histiocytic necrotizing lymphadentis, is a rare, benign and self-limited disease, with unknown etiology, that affects mainly young women, and is characterized by adenopathy (usually localized in the cervical region) and fever. Diagnosis is based on histopathological findings in ganglionar tissue obtained in excisional biopsy, which allows, in most cases, the differential diagnosis with other similar clinical conditions, but which have a completely different clinical evolution and therapeutic needs. We report a case of a twenty four year old woman with persistent cervical lymphadenopathy, in which histopathological examination followed by immunohistochemical analysis of ganglionar tissue revealed to be Kikuchi-Fujimoto disease.
authors.affiliation: Serviço de Medicina Interna, Hospital São Francisco Xavier (CHLO), Lisbon, Portugal.
authors.forename: Inês
authors.initials: I
authors.lastname: Antunes
authors.forename: Arturo
authors.initials: A
authors.lastname: Botella
authors.forename: Filipa
authors.initials: F
authors.lastname: Marques
authors.forename: Inês
authors.initials: I
authors.lastname: Araújo
authors.forename: Ana
authors.initials: A
authors.lastname: Abreu
authors.forename: Rosa
authors.initials: R
authors.lastname: Cardiga
authors.forename: Ana
authors.initials: A
authors.lastname: Leitão
authors.forename: Cândida
authors.initials: C
authors.lastname: Fonseca
authors.forename: Fátima
authors.initials: F
authors.lastname: Ceia
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology*; D009333:Neck; D014057:Tomography, X-Ray Computed; D055815:Young Adult