title: Antiemetic efficacy of promethazine on xylazine-induced emesis in cats.
abstract: The prophylactic antiemetic effect of 3 dosages of promethazine injected into cats 1 h before administration of xylazine was compared with that of a saline solution. Prior treatment with 2 and 4 mg/kg of promethazine significantly reduced the frequency of emetic episodes. Promethazine may be used as a prophylactic antiemetic in cats treated with xylazine.
authors.affiliation: Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tabriz, Iran. skolahian@tabrizu.ac.ir
authors.forename: Saeed
authors.initials: S
authors.lastname: Kolahian
authors.forename: Seyed Hosein
authors.initials: SH
authors.lastname: Jarolmasjed
mesh_terms: D058647:Adrenergic alpha-2 Receptor Agonists / Q000008:administration & dosage* / Q000009:adverse effects; D000818:Animals; D000932:Antiemetics / Q000627:therapeutic use*; D002371:Cat Diseases / Q000517:prevention & control*; D002415:Cats; D004305:Dose-Response Relationship, Drug; D005260:Female; D008297:Male; D011398:Promethazine / Q000627:therapeutic use*; D014839:Vomiting / Q000517:prevention & control / Q000662:veterinary*; D014991:Xylazine / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D058647:Adrenergic alpha-2 Receptor Agonists; D000932:Antiemetics; D014991:Xylazine; D011398:Promethazine