title: Haematobium eggs detection in human bladder cancer and sporocysts in snail vectors: Seven cases report and a review of the Burkina Faso literature.
abstract: Schistosoma haematobium plays a central role in the development of bladder cancer in Burkina Faso. The objective of this study was to determine the presence of S. haematobium in the bladder cancer and in vector snails. For the first time, formalin-fixed tissues embedded in paraffin were analyzed by immunohistochemistry and PCR. Molecular detection has resulted in 7/7 positive bladder cancer. Finally, as the snail vectors were positive. We suggest the use of molecular methods in the snail vectors for the detection of cysts and in cancerous tissues in larger studies.
authors.affiliation: 2nd Department of Pathology, Spedali Civili, University of Brescia, viale Europa 11, 25123 Brescia, Italy. l.benerini@virgilio.it
authors.forename: L
authors.initials: L
authors.lastname: Benerini Gatta
authors.forename: P
authors.initials: P
authors.lastname: Balzarini
authors.forename: M
authors.initials: M
authors.lastname: Cadei
authors.forename: F
authors.initials: F
authors.lastname: Castelli
authors.forename: P
authors.initials: P
authors.lastname: Grigolato
mesh_terms: D000818:Animals; D002050:Burkina Faso; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000469:parasitology*; D004199:Disease Vectors; D004531:Eggs; D006801:Humans; D033661:Oocysts / Q000473:pathology*; D012548:Schistosoma haematobium / Q000235:genetics / Q000302:isolation & purification* / Q000378:metabolism; D012553:Schistosomiasis haematobia / Q000150:complications* / Q000469:parasitology; D012908:Snails / Q000469:parasitology*; D001749:Urinary Bladder Neoplasms / Q000209:etiology* / Q000469:parasitology*