title: Quinone-dependent alcohol dehydrogenases and FAD-dependent alcohol oxidases.
abstract: This review considers quinone-dependent alcohol dehydrogenases and FAD-dependent alcohol oxidases, enzymes that are present in numerous methylotrophic eu- and prokaryotes and significantly differ in their primary and quaternary structure. The cofactors of the enzymes are bound to the protein polypeptide chain through ionic and hydrophobic interactions. Microorganisms containing these enzymes are described. Methods for purification of the enzymes, their physicochemical properties, and spatial structures are considered. The supposed mechanism of action and practical application of these enzymes as well as their producers are discussed.
authors.affiliation: Biosensor AN Ltd., pr. Akademika Semenova 1, 142432 Chernogolovka, Moscow Region, Russia. gari@icp.ac.ru
authors.forename: A R
authors.initials: AR
authors.lastname: Gvozdev
authors.forename: I A
authors.initials: IA
authors.lastname: Tukhvatullin
authors.forename: R I
authors.initials: RI
authors.lastname: Gvozdev
mesh_terms: D000426:Alcohol Dehydrogenase / Q000737:chemistry / Q000378:metabolism*; D000429:Alcohol Oxidoreductases / Q000737:chemistry / Q000378:metabolism*; D000818:Animals; D016227:Benzoquinones / Q000737:chemistry / Q000378:metabolism*; D005182:Flavin-Adenine Dinucleotide / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D008958:Models, Molecular; D015394:Molecular Structure
chemical_list: D016227:Benzoquinones; D005182:Flavin-Adenine Dinucleotide; C004532:quinone; D000429:Alcohol Oxidoreductases; D000426:Alcohol Dehydrogenase; C019643:alcohol oxidase