title: Changes in overnight arterial oxygen saturation after mandibular setback.
abstract: Mandibular setback reduces space in the pharyngeal airway, and it has been suggested that it might induce sleep-disordered breathing. We report on its effects on space in the pharyngeal airway and respiratory function during sleep. We studied 78 patients (29 men and 49 women) in whom skeletal class III malocclusions had been corrected. The mean (range) age at operation was 24 (16-38) years and body mass index (BMI) 21.4 (16.1-30 .9)kg/m(2). Morphological changes were evaluated on lateral cephalograms taken three times: preoperatively, a few days postoperatively, and more than 6 months postoperatively. Overnight arterial oxygen saturation (SpO2) was measured by pulse oximetry 6 times: preoperatively, and on days 1, 3, 5, and 7, and 6 months postoperatively; oximetric indices were calculated. Those immediately after mandibular setback were significantly worse than those preoperatively, although they gradually improved. There were positive correlations between BMI and oximetric indices, and little association between changes in mandibular position and oximetric indices. There was no evidence of sleep-disordered breathing 6 months after mandibular setback because most patients adapt to the new environment for respiratory function during sleep. However, some (particularly obese) patients may develop sleep-disordered breathing just after mandibular setback. In such patients attention should be paid to respiratory function during sleep in the immediate postoperative period, and careful postoperative follow-up is needed.
authors.affiliation: Division of Reconstructive Surgery for Oral and Maxillofacial Region, Department of Tissue Regeneration and Reconstruction, Course for Oral Life Science, Niigata University Graduate School of Medical and Dental Sciences, 2-5274 Gakkocho-Dori, Cyuo-Ku, Niigata City 951-8514, Japan. tadaharu@dent.niigata-u.ac.jp
authors.forename: Tadaharu
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Akinori
authors.initials: A
authors.lastname: Funayama
authors.forename: Daichi
authors.initials: D
authors.lastname: Hasebe
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Kato
authors.forename: Michiko
authors.initials: M
authors.lastname: Yoshizawa
authors.forename: Chikara
authors.initials: C
authors.lastname: Saito
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology; D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D002508:Cephalometry / Q000379:methods; D005146:Facial Asymmetry / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008313:Malocclusion, Angle Class III / Q000601:surgery; D008334:Mandible / Q000473:pathology; D063168:Mandibular Osteotomy / Q000379:methods*; D008437:Maxilla / Q000473:pathology; D009295:Nasal Bone / Q000473:pathology; D024343:Open Bite / Q000601:surgery; D019340:Osteotomy, Le Fort / Q000379:methods; D059229:Osteotomy, Sagittal Split Ramus / Q000379:methods; D010092:Oximetry; D010100:Oxygen / Q000097:blood*; D010614:Pharynx / Q000473:pathology; D011183:Postoperative Complications / Q000517:prevention & control; D012119:Respiration; D012658:Sella Turcica / Q000473:pathology; D012890:Sleep / Q000502:physiology; D020181:Sleep Apnea, Obstructive / Q000517:prevention & control; D014716:Vertical Dimension; D055815:Young Adult
chemical_list: D010100:Oxygen