title: Flow characteristics of LIMA radial composite sequential bypass grafting and single LIMA and saphenous vein sequential bypass grafting performed under OPCAB.
abstract: OBJECTIVE
  The present study was aimed to compare the hemodynamic flow characteristics of LIMA radial artery composite sequential bypass grafting and with single LIMA and saphenous vein sequential bypass grafting performed by off-pump coronary artery bypass grafting (OPCAB).
  
  
  METHODS
  Between March 2007 and February 2008, 121 OPCAB patients were prospectively divided into two groups; Group I (N.=70, left internal thoracic artery [LITA]-left anterior descending [LAD] and Ao-SV sequential grafting), and Group II (N.=51, LITA-RA sequential grafting). The mean flow, pulsatility index (PI) and back flow (BF) were measured using the Transit-time flow meter (TTFM). In Group II, the proximal (p-LITA) and distal LITA (d-LITA) flow in relation to the RA side branch anastomosis were measured separately.
  
  
  RESULTS
  The mean flow and PI of the proximal SV sequential graft and that of the RA graft were 64.4 ± 37.3 mL/min and 2.6 ± 1.6 versus 27.3 ± 18.6 mL/min and 4.1 ± 4.4, respectively (P<0.05). In Group I, the mean LITA flow, PI, and BF were 26.9 ± 16.4 mL/min, 2.6 ± 1.5, and 3.1 ± 6.1% whereas in Group II those of the p-LITA were 37.3 ± 21.6 mL/min, 2.3 ± 1.0, and 2.0 ± 3.5% and the d-LITA were 18.8 ± 12.2 mL/min, 3.9 ± 3.3 and 7.4 ± 11.8% (P<0.01).
  
  
  CONCLUSIONS
  The results of the present data suggest the hemodynamic flow characteristics of composite bypass grafting to be inferior to the single LIMA and separate aorta-saphenous vein bypass grafting strategy. However, a longer follow up is warranted to assess the implications of these findings on graft durability.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Anam Hospital, Korea University Medical Center, Seoul, Korea.
authors.forename: J S
authors.initials: JS
authors.lastname: Jung
authors.forename: C H
authors.initials: CH
authors.lastname: Chung
authors.forename: S H
authors.initials: SH
authors.lastname: Lee
authors.forename: S H
authors.initials: SH
authors.lastname: Cho
authors.forename: J H
authors.initials: JH
authors.lastname: Lee
authors.forename: J G
authors.initials: JG
authors.lastname: Ryu
authors.forename: H
authors.initials: H
authors.lastname: Song
authors.forename: J W
authors.initials: JW
authors.lastname: Lee
authors.forename: S J
authors.initials: SJ
authors.lastname: Choo
mesh_terms: D000368:Aged; D001783:Blood Flow Velocity; D016009:Chi-Square Distribution; D047549:Coronary Artery Bypass, Off-Pump / Q000009:adverse effects / Q000379:methods*; D003326:Coronary Circulation; D023921:Coronary Stenosis / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011673:Pulsatile Flow; D017534:Radial Artery / Q000503:physiopathology / Q000637:transplantation*; D012039:Regional Blood Flow; D056910:Republic of Korea; D012501:Saphenous Vein / Q000503:physiopathology / Q000637:transplantation*; D016896:Treatment Outcome