title: Cytomegalovirus bearing in children with sensorineural hearing losses.
abstract: The rate of bearing of cytomegalovirus, CMV, has been estimated in children suffering from inborn or newborn types of a sensorineural hearing loss of hard-to-severe degrees. The test group comprised 15 hearing-loss children of 3-6 years of age. The control group included accidentally selected 30 healthy children of the same age without any hearing complains. In both groups the CMV-specific IgG antibodies were determined in blood via the enzyme-linked immunosorbent assay, ELISA. The excessive amount of IgG antibodies was found in 14 out of 15 children with sensorineural hearing losses being estimated objectively, via computer registration of auditory brainstem responses, ABRs, and in 14 out of 30 children with normal hearing, being also inspected objectively, via specialized screening procedure. The intergroup difference in CMV bearing rates, 93.3% and 46.7%, respectively, has been confirmed to be statistically significant (p=0.007). CMV bearing happens thus twice as much in sensorineural hearing-loss than in normally-hearing children. Early detection of a hearing loss and early assessment of CMV bearing seem essential for an immediate start and, consequently, for a batter chance of positive outcomes of specific treatment-rehabilitation means.
authors.affiliation: Tbilisi State Medical University, Tbilisi, Georgia.
authors.forename: T
authors.initials: T
authors.lastname: Devdariani
authors.forename: N
authors.initials: N
authors.lastname: Chibalashvili
authors.forename: M
authors.initials: M
authors.lastname: Tushishvili
authors.forename: K
authors.initials: K
authors.lastname: Gogberashvili
authors.forename: Z
authors.initials: Z
authors.lastname: Kevanishvili
mesh_terms: D002648:Child; D002675:Child, Preschool; D003587:Cytomegalovirus / Q000302:isolation & purification / Q000472:pathogenicity; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000097:blood* / Q000473:pathology / Q000821:virology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male
chemical_list: D007074:Immunoglobulin G