title: [Spectral and functional properties of ceruloplasmin under UV irradiation].
abstract: During oxydase reaction spectral characteristics of ceruloplasmin at absorption of copper ions and protein part of the molecule are shown to change. It has been ascertained, that when irradiating ceruloplasmin by UV-light the functioning of intramolecular electron transport chain is broken, the degree of positive cooperativity (a Hill's constant) on substrate decreases. It is supposed, that these changes are caused by disturbance of interdomain interactions in a protein molecule.
authors.forename: V G
authors.initials: VG
authors.lastname: Artiukhov
authors.forename: O V
authors.initials: OV
authors.lastname: Basharina
authors.forename: M V
authors.initials: MV
authors.lastname: Bragin
authors.forename: D Iu
authors.initials: DIu
authors.lastname: Sukhanov
authors.forename: G A
authors.initials: GA
authors.lastname: Vashanov
mesh_terms: D000042:Absorption; D002570:Ceruloplasmin / Q000737:chemistry* / Q000528:radiation effects*; D003300:Copper / Q000737:chemistry; D006801:Humans; D010084:Oxidation-Reduction / Q000528:radiation effects; D013056:Spectrophotometry, Ultraviolet; D014466:Ultraviolet Rays
chemical_list: D003300:Copper; D002570:Ceruloplasmin