title: [Comparative study between gelatinous and hard spheres of silicone in rabbit eviscerated scleral cavity].
abstract: OBJECTIVE
  To evaluate and to compare the biocompatibility of gelatinous and hard silicone spheres placed into eviscerated scleral cavities of rabbits.
  
  
  METHODS
  Thirty rabbits underwent right eye evisceration surgery and replacement of orbital volume using gelatinous (Group I) or hard silicone (Group II) spheres. Seven, 30 and 90 days after the surgical procedure, clinical assessment, ultrasound of the orbit, histological and morphometric evaluation of the pseudocapsule were performed. Data was submitted to statistical analysis.
  
  
  RESULTS
  Similarity of tissue response was observed with both materials. Two gelatinous and one hard silicone spheres had extrusion. The pseudocapsule around the gelatinous spheres was better organized, thinner and with less inflammatory reaction.
  
  
  CONCLUSIONS
  Both spheres had good integration to the orbital tissue in rabbit eviscerated cavities.
authors.affiliation: Faculdade de Medicina de Botucatu, Universidade Estadual Paulista "Júlio de Mesquita Filho," Brasil. sartioli@fmb.unesp.br
authors.forename: Mayumi Shirota
authors.initials: MS
authors.lastname: Kanamura
authors.forename: Carlos Roberto
authors.initials: CR
authors.lastname: Padovani
authors.forename: Elenize Jamas
authors.initials: EJ
authors.lastname: Pereira
authors.forename: Maria Jaqueline
authors.initials: MJ
authors.lastname: Mamprim
authors.forename: Silvana Artioli
authors.initials: SA
authors.lastname: Schellini
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000627:therapeutic use*; D017234:Eye Evisceration / Q000379:methods*; D005782:Gels; D008422:Materials Testing; D023421:Models, Animal; D020273:Orbital Implants; D011184:Postoperative Period; D019919:Prosthesis Implantation / Q000379:methods; D011817:Rabbits; D011897:Random Allocation; D012590:Sclera / Q000601:surgery*; D012828:Silicones / Q000627:therapeutic use*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials; D005782:Gels; D012828:Silicones