title: Focal parietal necrosis of the sigmoid due to atypical neuroleptics: a case report.
abstract: We present the case of a 26-year-old man with schizoid personality disorder who suffered from a very focal and transparietal necrosis of the sigmoid after an overdose of atypical neuroleptics. This is a singular, rather unknown and potentially lethal side effect of these drugs. The physiopathology of this complication is multifactorial.
authors.affiliation: Department of Gastroenterology, Diagnostic Radiology, Visceral Surgery, Clinique St Luc, Bouge, Namur, Belgium. arnaud.devresse@proximus.be
authors.forename: Arnaud
authors.initials: A
authors.lastname: Devresse
authors.forename: Philippe
authors.initials: P
authors.lastname: Maldague
authors.forename: Bruno
authors.initials: B
authors.lastname: Coulier
authors.forename: Frédéric
authors.initials: F
authors.lastname: Pierard
authors.forename: Isabelle
authors.initials: I
authors.lastname: Gielen
mesh_terms: D000328:Adult; D014151:Anti-Anxiety Agents / Q000506:poisoning; D000927:Anticonvulsants / Q000506:poisoning; D000928:Antidepressive Agents / Q000506:poisoning; D014150:Antipsychotic Agents / Q000506:poisoning*; D015283:Citalopram / Q000506:poisoning; D003006:Clopenthixol / Q000506:poisoning; D003987:Dibenzothiazepines / Q000506:poisoning; D062787:Drug Overdose / Q000150:complications; D020345:Enterocolitis, Necrotizing / Q000139:chemically induced* / Q000601:surgery; D006801:Humans; D000077213:Lamotrigine; D008140:Lorazepam / Q000506:poisoning; D008297:Male; D000069348:Quetiapine Fumarate; D012557:Schizoid Personality Disorder / Q000188:drug therapy; D014196:Trazodone / Q000506:poisoning; D014227:Triazines / Q000506:poisoning
chemical_list: D014151:Anti-Anxiety Agents; D000927:Anticonvulsants; D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D003987:Dibenzothiazepines; D014227:Triazines; D015283:Citalopram; D000069348:Quetiapine Fumarate; D003006:Clopenthixol; D008140:Lorazepam; D000077213:Lamotrigine; D014196:Trazodone; C084602:clothiapine