title: Delineation of optic radiation and stria of Gennari on high-resolution phase difference enhanced imaging.
abstract: OBJECTIVE
  Phase difference enhanced (PADRE) imaging technique can selectively enhanced the phase difference between the target and surrounding tissue. Our purpose is to assess the delineations of the optic radiation and primary visual cortex (stria of Gennari) using PADRE.
  
  
  METHODS
  The subjects were 6 healthy volunteers. Axial and coronal high-spatial resolution PADRE images were acquired covering the entire optic radiation using a 3T magnetic resonance system. Two radiologists evaluated the PADRE and susceptibility-weighted imaging (SWI)-like images for the delineation of four layers at the optic radiation (tapetum, internal sagittal stratum, external sagittal stratum, and adjacent white matter) on the basis of the anatomic appearances of the cadaveric specimens stained with Bodian's method and Kluver-Barrera method. The radiologists also assessed the delineations of the stria of Gennari on PADRE and SWI-like images.
  
  
  RESULTS
  In all 6 healthy subjects, the PADRE images clearly identified the four layers at the optic radiation, as well as the stria of Gennari, which were difficult to appreciate in SWI-like images. The anatomic appearances of the optic radiation on PADRE images were more similar to those seen in the specimens stained with Kluver-Barrera method than with Bodian's method.
  
  
  CONCLUSIONS
  The PADRE technique can delineate the four layers at the optic radiation and the stria of Gennari; the differences in myelin densities can also be enhanced. The PADRE technique may have the potential to reinforce the clinical utility of MRI in the diagnosis of diseases that affect the optic radiation and primary visual cortex.
authors.affiliation: Department of Radiology, University of Occupational and Environmental Health School of Medicine, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan. s-ide@med.uoeh-u.ac.jp
authors.forename: Satoru
authors.initials: S
authors.lastname: Ide
authors.forename: Shingo
authors.initials: S
authors.lastname: Kakeda
authors.forename: Yukunori
authors.initials: Y
authors.lastname: Korogi
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Yoneda
authors.forename: Johji
authors.initials: J
authors.lastname: Nishimura
authors.forename: Toru
authors.initials: T
authors.lastname: Sato
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Hiai
authors.forename: Norihiro
authors.initials: N
authors.lastname: Ohnari
authors.forename: Masanori
authors.initials: M
authors.lastname: Takahashi
authors.forename: Kenji
authors.initials: K
authors.lastname: Hachisuka
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Fujiwara
authors.forename: Atsuji
authors.initials: A
authors.lastname: Matsuyama
mesh_terms: D000328:Adult; D000465:Algorithms; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009900:Optic Nerve / Q000033:anatomy & histology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014793:Visual Cortex / Q000033:anatomy & histology*; D014795:Visual Pathways / Q000033:anatomy & histology*