title: Detection of ovarian cancer by determination of CA 125 in different patohistologycal types of tumor according to age.
abstract: During the eighteen-year period in "Sestre milosrdnice" University Hospital Center, Zagreb, 271 women with ovarian tumor was studied. 229 women with ovarian cancer and 42 with borderline tumor. The pathohistological types of tumors were different. The age of the patients ranged from 20-83 years. In all patients the value of biochemical marker CA125 was determined. The aim of this study was to determine the usefulness of CA125 measurement in different age groups and in different patohistologycal forms of tumor. CA125 has proven to be positive in 89.1% of women with ovarian cancer and in 62% with neoplasm of low malignant potential. The higher values of CA125 were detected in younger women with low malignant tumor potential. Serous and metastatic tumor types were also associated with higher values of CA125.
authors.affiliation: University of Zagreb, "Sestre milosrdnice" University Hospital Center, Department of Gynecology and Obstetrics, Zagreb, Croatia. hsoljacicvranes@hotmail.com
authors.forename: Hrvojka Soljacić
authors.initials: HS
authors.lastname: Vranes
authors.forename: Petar
authors.initials: P
authors.lastname: Klarić
authors.forename: Krunoslav
authors.initials: K
authors.lastname: Kuna
authors.forename: Zdenko
authors.initials: Z
authors.lastname: Kraljević
authors.forename: Vesna
authors.initials: V
authors.lastname: Gall
authors.forename: Marija
authors.initials: M
authors.lastname: Jukić
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000097:blood* / Q000473:pathology*; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000097:blood*; D018394:CA-125 Antigen / Q000097:blood*; D018269:Carcinoma, Endometrioid / Q000097:blood / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000097:blood* / Q000473:pathology*; D013724:Teratoma / Q000097:blood / Q000473:pathology; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor; D018394:CA-125 Antigen