title: Treatment of recurrent hypoglycemia with plasmapheresis and steroid in nondiabetic patient.
abstract: We recently encountered a 35-year old man who suffered from frequent hypoglycemia. His blood test revealed the presence of high and suppressed level of insulin with supressed C-peptide levels, hypothalamic-pituitary axis was normal response in hypoglycemia and negative for anti-insulin antibody. Endocrinological and imaging data eliminated the possibility of insulinoma. His symptoms responded well to the therapy of prednisolone (60 mg/day) and plasmapheresis. We followed up the patient over the subsequent 6 months without remarkable lesions. He has had no further recurrences of hypoglycemia. We believe that the antiinsulin receptor antibody might have induced hypoglycemia in this patient.
authors.affiliation: Department of Internal Medicine, Division of Endocrinology and Metabolism, Selcuk University, Meram School of Medicine, Konya, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Kulaksızoglu
authors.forename: Mustafa Sait
authors.initials: MS
authors.lastname: Gonen
authors.forename: Levent
authors.initials: L
authors.lastname: Kebapcilar
authors.forename: Fatih
authors.initials: F
authors.lastname: Sahin
authors.forename: Fatih
authors.initials: F
authors.lastname: Demirci
authors.forename: Ali
authors.initials: A
authors.lastname: Topcu
mesh_terms: D000328:Adult; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy / Q000628:therapy*; D008297:Male; D010956:Plasmapheresis / Q000379:methods*; D011239:Prednisolone / Q000627:therapeutic use*
chemical_list: D011239:Prednisolone