title: [An analysis of effectiveness of application of various methods of artificial detoxication in patients with sterile phase of pancreatic necroses].
abstract: The presented work is based on an analysis of results of conservative and surgical treatment of 65 patients in sterile phase of pancreatic necrosis with the application of various methods of artificial detoxication. Increased efficiency of extracorporal detoxication methods is achieved by an individual selection of the detoxication method depending on the basic clinico-laboratory indicators of toxemia, phases of endogenic intoxication and accounting the mechanism of action of the methods. In the favorable course of the disease against the background of complex treatment using artificial detoxication methods decreased the basic clinico-laboratory indicators used for monitoring the level of endotoxemia and incompetence of the detoxicated bodies and systems as well as of severity of the general condition of the patients. Results of the research performed point to the greater role of using the extracomporal detoxication methods in complex treatment of acute destructive pancreatitis.
authors.forename: V V
authors.initials: VV
authors.lastname: Savel'ev
authors.forename: M M
authors.initials: MM
authors.lastname: Vinokurov
authors.forename: N M
authors.initials: NM
authors.lastname: Gogolev
authors.forename: A F
authors.initials: AF
authors.lastname: Potapov
mesh_terms: D000328:Adult; D005112:Extracorporeal Circulation / Q000379:methods*; D005260:Female; D006464:Hemoperfusion / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis / Q000503:physiopathology / Q000601:surgery*; D010179:Pancreas / Q000473:pathology*; D019283:Pancreatitis, Acute Necrotizing / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D018579:Patient Selection; D012720:Severity of Illness Index; D016896:Treatment Outcome