title: Chromatin and pluripotency: the MYSTerious connection.
abstract: Although histone acetylation is critical for maintaining embryonic stem cell pluripotency, the molecular machinery involved remains poorly understood. Li et al. (2012) now show that Mof, a MYST family histone acetyltransferase, functions as a coactivator of Nanog-mediated transcription, maintains the expression of pluripotency-associated genes, and primes developmental genes for differentiation.
authors.affiliation: Yale Stem Cell Center, Department of Genetics, Yale University, New Haven, CT 06520, USA.
authors.forename: Anna
authors.initials: A
authors.lastname: Kloc
authors.forename: Natalia
authors.initials: N
authors.lastname: Ivanova