title: Epidemiological aspects of HCV infection in HIV-infected individuals in Piauí State, Northeast Brazil.
abstract: In this study, the prevalence, genotypic frequency, and risk factors for HCV infection in 768 patients infected with HIV were determined. Fifty-two (6.77 %) HIV-positive individuals had anti-HCV antibodies and 26 (3.39 %) had HCV-RNA. Genotyping results indicated that all RT-PCR samples from patients infected with HCV belonged to genotype 1. Multivariate analysis revealed an association of HIV-HCV coinfection with drug use and having received blood transfusions before 1994. The relatively low prevalence of HCV infection in the HIV-positive population in that region may be a consequence of the small number of drug users in the sample, despite a strong association between HCV infection and drug use.
authors.affiliation: Campus do Marajó-Breves, Universidade Federal do Pará, Breves, PA, Brasil. olivfilho@ufpa.br
authors.forename: Aldemir B
authors.initials: AB
authors.lastname: Oliveira-Filho
authors.forename: Evaldo H
authors.initials: EH
authors.lastname: Oliveira
authors.forename: Jairo A A
authors.initials: JA
authors.lastname: Castro
authors.forename: Letiano V
authors.initials: LV
authors.lastname: Silva
authors.forename: Antonio C R
authors.initials: AC
authors.lastname: Vallinoto
authors.forename: José Alexandre R
authors.initials: JA
authors.lastname: Lemos
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D001938:Brazil / Q000453:epidemiology; D005260:Female; D014644:Genetic Variation; D005838:Genotype; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology; D016174:Hepacivirus / Q000145:classification* / Q000235:genetics / Q000276:immunology; D006526:Hepatitis C / Q000150:complications* / Q000453:epidemiology / Q000821:virology; D006801:Humans; D008297:Male; D016017:Odds Ratio; D010802:Phylogeny; D015995:Prevalence; D012367:RNA, Viral / Q000032:analysis; D012307:Risk Factors
chemical_list: D000914:Antibodies, Viral; D012367:RNA, Viral