title: The Kulinkovich hydroxycyclopropanation reaction in natural product synthesis.
abstract: The Kulinkovich cyclopropanation reaction provides a flexible and convenient method for the synthesis of cyclopropanols. Together with the diverse chemistry of the cyclopropanol unit, it offers access to a wide range of functionalised unsaturated and saturated compounds. The successful use in the synthesis of natural compounds is outlined in this perspective.
authors.affiliation: University of Auckland, School of Chemical Sciences, 23 Symonds Street, Auckland 1043, New Zealand.
authors.forename: Isabell
authors.initials: I
authors.lastname: Haym
authors.forename: Margaret A
authors.initials: MA
authors.lastname: Brimble
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry; D003500:Cyclization; D003521:Cyclopropanes / Q000737:chemistry*; D004952:Esters / Q000737:chemistry; D004988:Ethers, Cyclic / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D001688:Biological Products; D002264:Carboxylic Acids; D003521:Cyclopropanes; D004952:Esters; D004988:Ethers, Cyclic; C043657:cyclopropanol