title: [Thoracic surgery in patients with autoimmune diseases].
abstract: Autoimmune diseases arise from an inappropriate immune response against substances and tissues normally present in the body. Although the pathogenesis are still unclear, several autoimmune diseases, such as dermatomyositis, systemic sclerosis, have a higher incidence of thoracic neoplasm. Also in the mediastinum several autoimmune diseases are known to associate thymoma. While the manifestations of the disease diverse, administration of immunosuppressant are commonly used for the management of aberrant immune response. Immunosuppressive therapies likely to increase susceptibility to infections and associate other side-effects, which could increase the risk of surgery and complicate the perioperative management. In this article we discuss the autoimmune diseases which are known to associate with thoracic and mediastinal neoplasms, and the perioperative management of thoracic surgery in patients with autoimmune diseases.
authors.affiliation: Department of Thoracic Surgery, Osaka Prefectural Medical Center for Respiratory and Allergic Diseases, Habikino, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kadota
authors.forename: M
authors.initials: M
authors.lastname: Ohta
mesh_terms: D001327:Autoimmune Diseases / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000601:surgery; D013899:Thoracic Neoplasms / Q000601:surgery; D019616:Thoracic Surgical Procedures