title: A novel steroidal alkaloid from Fritillaria shuchengensis.
abstract: A novel steroidal alkaloid, suchengbeisine (1), along with two known steroidal alkaloids, N-oxide of verticinone (2) and zhebeininoside (3), were isolated from the bulbs of Fritillaria shuchengensis S. C. Chen et S. F. Yin. The structures of these compounds were elucidated by intensive spectroscopic methods, including NMR, IR, CD and MS.
authors.affiliation: School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, Sichuan, People's Republic of China.
authors.forename: Shuai
authors.initials: S
authors.lastname: Huang
authors.forename: Xian-li
authors.initials: XL
authors.lastname: Zhou
authors.forename: Juan
authors.initials: J
authors.lastname: Wen
authors.forename: Cui-juan
authors.initials: CJ
authors.lastname: Wang
authors.forename: Hong-yan
authors.initials: HY
authors.lastname: Wang
authors.forename: Lian-hai
authors.initials: LH
authors.lastname: Shan
authors.forename: Jie
authors.initials: J
authors.lastname: Weng
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018938:Caco-2 Cells; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002595:Cevanes / Q000302:isolation & purification; D004305:Dose-Response Relationship, Drug; D031410:Fritillaria / Q000737:chemistry*; D006367:HeLa Cells; D056945:Hep G2 Cells; D006801:Humans; D020128:Inhibitory Concentration 50; D061986:MCF-7 Cells; D015394:Molecular Structure; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000470:Alkaloids; D002595:Cevanes; D010840:Phytosterols; D013256:Steroids; C000588495:suchengbeisine; C014242:verticine