title: Primary disseminated extrapulmonary multidrug resistant tuberculosis.
abstract: Disseminated tuberculosis is a common mode of presentation of tuberculosis in patients both with and without HIV/AIDS in India. However, primary multidrug resistance in disseminated tuberculosis involving only the extrapulmonary sites in an immunocompetent adult is rare. Here, we report a case of a 19-year-old man who had disseminated tuberculosis involving left pleura, pericardium, peritoneum and intraabdominal lymph nodes. He was initially taking WHO category I antituberculous drugs, but was not responding in spite of 5 months of chemotherapy. Culture of the pleural biopsy specimen grew Mycobacterium tuberculosis which was resistant to isoniazid and rifampicin. He was put on therapy for multidrug resistant tuberculosis,following 24 months of chemotherapyhe had an uneventful recovery.
authors.affiliation: Department of Respiratory Medicine, Medical College, Kolkata, West Bengal, India.
authors.forename: S K
authors.initials: SK
authors.lastname: Das
authors.forename: A
authors.initials: A
authors.lastname: Das
authors.forename: A
authors.initials: A
authors.lastname: Gangopadhyay
authors.forename: A K
authors.initials: AK
authors.lastname: Sinha
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial; D004452:Echocardiography; D006801:Humans; D007194:India; D008297:Male; D009169:Mycobacterium tuberculosis / Q000187:drug effects* / Q000302:isolation & purification*; D010994:Pleura / Q000473:pathology; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018088:Tuberculosis, Multidrug-Resistant / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology*; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents