title: Potential impact of interventions resulting in reduced exposure to ultraviolet (UV) radiation (UVA and UVB) on skin cancer incidence in four European countries, 2010-2050.
abstract: BACKGROUND
  Behavioural interventions to reduce exposure to ultraviolet radiation (UVR) can reduce risk of skin cancer.
  
  
  OBJECTIVE
  To integrate the data and to evaluate the impact of interventions to limit exposure to UVR on skin cancer incidence in four selected countries.
  
  
  METHODS
  Using PREVENT, a dynamic simulation model, we modelled the potential for skin cancer prevention in four European countries under various scenarios to avoid damage by UVR.
  
  
  RESULTS
  In general, the most effective interventions were those aimed at protecting people during outdoor work and outdoor hobbies against the harmful effects of UVR, and combinations of several interventions. These could in theory lead to reductions of up to 45% in skin cancer cases projected for the year 2050.
  
  
  CONCLUSIONS
  The scope for prevention depends on the prevalence of the risk factors in the different countries, as well as the associated risk factors and time lags modelled.
authors.affiliation: Department of Public Health, Erasmus MC University Medical Center, Rotterdam, The Netherlands. e.devries@erasmusmc.nl
authors.forename: E
authors.initials: E
authors.lastname: de Vries
authors.forename: M
authors.initials: M
authors.lastname: Arnold
authors.forename: E
authors.initials: E
authors.lastname: Altsitsiadis
authors.forename: M
authors.initials: M
authors.lastname: Trakatelli
authors.forename: B
authors.initials: B
authors.lastname: Hinrichs
authors.forename: E
authors.initials: E
authors.lastname: Stockfleth
authors.forename: J
authors.initials: J
authors.lastname: Coebergh
mesh_terms: D000368:Aged; D002280:Basal Cell Carcinoma / Q000453:epidemiology / Q000517:prevention & control*; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000517:prevention & control*; D005060:Europe / Q000453:epidemiology; D005260:Female; D015438:Health Behavior; D006801:Humans; D015994:Incidence; D008297:Male; D008545:Melanoma / Q000453:epidemiology / Q000517:prevention & control*; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology / Q000517:prevention & control*; D015995:Prevalence; D012307:Risk Factors; D012878:Skin Neoplasms / Q000453:epidemiology / Q000517:prevention & control*; D055108:Sunbathing / Q000706:statistics & numerical data; D013473:Sunscreening Agents / Q000627:therapeutic use; D014466:Ultraviolet Rays / Q000009:adverse effects*
chemical_list: D013473:Sunscreening Agents