title: Molecular immunology of allergic conjunctivitis.
abstract: OBJECTIVE
  Successful treatment of allergic eye disease depends on understanding the pathophysiology of ocular allergy. Thus, in this review, recent experimental and clinical research that has provided significant information about the immunopathology of allergic eye disease will be discussed.
  
  
  RESULTS
  Recently, role of various cells, cytokines and chemokines has been scrutinized in the immunopathogenesis of ocular allergy. In this respect, current research highlights contribution of special molecules and cells in the development and clinical features of immunoglobulin E (IgE) and T-cell-mediated eye allergies.
  
  
  CONCLUSIONS
  Recent findings in molecular immunology of ocular allergy, which comprise complex inflammatory conditions of the conjunctiva, have enabled us to better understand the pathophysiology of these diseases and have aided in the potential development of new therapeutic agents.
authors.affiliation: Hacettepe University, Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey. mirkec@hacettepe.edu.tr
authors.forename: Murat T
authors.initials: MT
authors.lastname: Irkec
authors.forename: Banu
authors.initials: B
authors.lastname: Bozkurt
mesh_terms: D003233:Conjunctivitis, Allergic / Q000276:immunology* / Q000503:physiopathology; D016207:Cytokines / Q000276:immunology / Q000378:metabolism*; D004804:Eosinophils / Q000276:immunology; D006801:Humans; D007249:Inflammation / Q000276:immunology / Q000503:physiopathology; D008407:Mast Cells / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D016207:Cytokines