title: Transcatheter aortic valve implantation: 10-year anniversary part II: clinical implications.
abstract: Transcatheter aortic valve implantation (TAVI) has been increasingly recognized as a curative treatment for severe aortic stenosis (AS). Despite important improvements in current device technology and implantation techniques, specific complications still remain and warrant consideration. Vascular complications and peri-procedural neurological events were the first concerns to emerge with this new technology. Recently, significant post procedural para-valvular leak has been shown to be more frequent after TAVI than after surgical aortic valve replacement (SAVR), and its potential association with worse long-term prognostic has raised concerns. In moving toward treatment of lower risk populations, structural integrity and long-term durability of heat valve prosthesis are becoming of central importance. Emerging technologies and newer generations of devices seem promising in dealing with these matters.
authors.affiliation: Columbia University Medical Center and the Cardiovascular Research Foundation, New York, NY, USA. pg2295@columbia.edu
authors.forename: Philippe
authors.initials: P
authors.lastname: Généreux
authors.forename: Stuart J
authors.initials: SJ
authors.lastname: Head
authors.forename: David A
authors.initials: DA
authors.lastname: Wood
authors.forename: Susheel K
authors.initials: SK
authors.lastname: Kodali
authors.forename: Mathew R
authors.initials: MR
authors.lastname: Williams
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Paradis
authors.forename: Marco
authors.initials: M
authors.lastname: Spaziano
authors.forename: A Pieter
authors.initials: AP
authors.lastname: Kappetein
authors.forename: John G
authors.initials: JG
authors.lastname: Webb
authors.forename: Alain
authors.initials: A
authors.lastname: Cribier
authors.forename: Martin B
authors.initials: MB
authors.lastname: Leon
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology; D001022:Aortic Valve Insufficiency / Q000209:etiology; D001024:Aortic Valve Stenosis / Q000628:therapy*; D001145:Arrhythmias, Cardiac / Q000209:etiology; D006328:Cardiac Catheterization / Q000009:adverse effects*; D054059:Coronary Occlusion / Q000209:etiology; D006335:Heart Injuries / Q000209:etiology; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects*; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D020521:Stroke / Q000209:etiology; D014652:Vascular Diseases / Q000209:etiology