title: Aptamer-based affinity labeling of proteins.
abstract: A most able label: Labeled aptamers can be cross-linked to their target structures in a light-dependent and highly specific manner as a result of a new strategy termed aptamer-based affinity labeling (ABAL) of proteins. The aptamer-protein complexes can be enriched in vitro, from a cellular lysate and from the surface of living cells, opening new ways to study aptamer interactions in biological contexts.
authors.affiliation: University of Bonn, LIMES Institute, Bonn, Germany.
authors.forename: Jan L
authors.initials: JL
authors.lastname: Vinkenborg
authors.forename: Günter
authors.initials: G
authors.lastname: Mayer
authors.forename: Michael
authors.initials: M
authors.lastname: Famulok
mesh_terms: D000345:Affinity Labels / Q000737:chemistry*; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D045744:Cell Line, Tumor; D006801:Humans; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism; D019859:Proto-Oncogene Proteins c-met / Q000737:chemistry / Q000378:metabolism; D052156:SELEX Aptamer Technique; D014466:Ultraviolet Rays
chemical_list: D000345:Affinity Labels; D052157:Aptamers, Nucleotide; D011506:Proteins; D019859:Proto-Oncogene Proteins c-met