title: Ventilatory responses to exercise training in obese adolescents.
abstract: The aim of this study was to examine ventilatory responses to training in obese adolescents. We assessed body composition, pulmonary function and ventilatory responses (among which expiratory flow limitation and operational lung volumes) during progressive cycling exercise in 16 obese adolescents (OB) before and after 12 weeks of exercise training and in 16 normal-weight volunteers. As expected, obese adolescents' resting expiratory reserve volume was lower and inversely correlated with thoraco-abdominal fat mass (r = -0.74, p<0.0001). OB presented lower end expiratory (EELV) and end inspiratory lung volumes (EILV) at rest and during submaximal exercise, and modest expiratory flow limitation. After training, OB increased maximal aerobic performance (+19%) and maximal inspiratory pressure (93.7±31.4 vs. 81.9±28.2 cm H2O, +14%) despite lack of decrease in trunk fat and body weight. Furthermore, EELV and EILV were greater during submaximal exercise (+11% and +9% in EELV and EILV, respectively), expiratory flow limitation delayed but was not accompanied by increased V(T). However, submaximal exertional symptoms (dyspnea and leg discomfort) were significantly decreased (-71.3% and -70.7%, respectively). Our results suggest that exercise training can improve pulmonary function at rest (static inspiratory muscle strength) and exercise (greater operating lung volumes and delayed expiratory flow limitation) but these modifications did not entirely account for improved dyspnea and exercise performance in obese adolescents.
authors.affiliation: Joseph Fourier University, Hypoxia Physiopathology Laboratory, Grenoble F-38000, France.
authors.forename: Monique
authors.initials: M
authors.lastname: Mendelson
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Michallet
authors.forename: François
authors.initials: F
authors.lastname: Estève
authors.forename: Claudine
authors.initials: C
authors.lastname: Perrin
authors.forename: Patrick
authors.initials: P
authors.lastname: Levy
authors.forename: Bernard
authors.initials: B
authors.lastname: Wuyam
authors.forename: Patrice
authors.initials: P
authors.lastname: Flore
mesh_terms: D000293:Adolescent; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000503:physiopathology* / Q000534:rehabilitation*; D012123:Pulmonary Ventilation / Q000502:physiology*; D012129:Respiratory Function Tests