title: The synthesis of 2-deoxy-α-D-glycosides from D-glycals catalyzed by TMSI and PPh3.
abstract: 2-Deoxyglycosides were synthesized in high α-selectivity by the direct addition of alcohols to D-glucal and D-galactal catalyzed by TMSI and PPh(3). The acid labile isopropylidene group is tolerated under this condition.
authors.affiliation: The State Key Laboratory of Natural and Biomimetic Drugs, Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Beijing 100191, PR China.
authors.forename: Xi-Kai
authors.initials: XK
authors.lastname: Cui
authors.forename: Ming
authors.initials: M
authors.lastname: Zhong
authors.forename: Xiang-Bao
authors.initials: XB
authors.lastname: Meng
authors.forename: Zhong-Jun
authors.initials: ZJ
authors.lastname: Li
mesh_terms: D002384:Catalysis; D003837:Deoxy Sugars / Q000138:chemical synthesis* / Q000737:chemistry; D003847:Deoxyglucose / Q000031:analogs & derivatives* / Q000737:chemistry; D006027:Glycosides / Q000138:chemical synthesis* / Q000737:chemistry; D006031:Glycosylation; D009682:Magnetic Resonance Spectroscopy; D014297:Trimethylsilyl Compounds / Q000737:chemistry*
chemical_list: D003837:Deoxy Sugars; D006027:Glycosides; D014297:Trimethylsilyl Compounds; C419804:trimethylsilyl iodide; C001289:d-glucal; D003847:Deoxyglucose