title: Selective multicolour imaging of zebrafish muscle fibres by using fluorescent organic nanoparticles.
abstract: Glowing fish: Fluorescent organic nanoparticles (FONs) were prepared from pyrene-containing guanine analogues. FONs are able to penetrate into human cells and zebrafish embryos; they are nontoxic, biocompatible and were found to be specific for muscular tissues. This study demonstrates for the first time the possibility of using FONs for in vivo, whole-body, fluorescence imaging of zebrafish.
authors.affiliation: Organic and Medicinal Chemistry, Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad, India.
authors.forename: E Ramanjaneya
authors.initials: ER
authors.lastname: Reddy
authors.forename: Rakesh Kumar
authors.initials: RK
authors.lastname: Banote
authors.forename: Kiranam
authors.initials: K
authors.lastname: Chatti
authors.forename: Pushkar
authors.initials: P
authors.lastname: Kulkarni
authors.forename: Marina S
authors.initials: MS
authors.lastname: Rajadurai
mesh_terms: D000818:Animals; D004625:Embryo, Nonmammalian / Q000648:ultrastructure*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D006147:Guanine / Q000031:analogs & derivatives; D006801:Humans; D008856:Microscopy, Fluorescence / Q000379:methods; D053758:Nanoparticles / Q000737:chemistry*; D061848:Optical Imaging; D011721:Pyrenes / Q000737:chemistry; D051598:Whole Body Imaging / Q000379:methods*; D015027:Zebrafish / Q000196:embryology*
chemical_list: D005456:Fluorescent Dyes; D011721:Pyrenes; D006147:Guanine; C030984:pyrene