title: Hidden dangers: a cryptic exon disrupts BRCA2 mRNA.
abstract: The first mutation that disrupts BRCA2 mRNA by including a novel, cryptic exon is reported in this issue. The mutation lies deep within an intron and would not have been detected by conventional screening methods. In the future, more mutations may be discovered by direct mRNA analysis.
authors.affiliation: Center for Clinical Cancer Genetics and Global Health, The University of Chicago Medical Center, Chicago, IL 60637, USA.
authors.forename: James D
authors.initials: JD
authors.lastname: Fackenthal
authors.forename: Younghee
authors.initials: Y
authors.lastname: Lee
authors.forename: Olufunmilayo I
authors.initials: OI
authors.lastname: Olopade
mesh_terms: D017398:Alternative Splicing; D005091:Exons; D005260:Female; D024522:Genes, BRCA2; D006801:Humans; D007438:Introns; D009154:Mutation