title: Chondroitin sulfate in the treatment of osteoarthritis: from in vitro studies to clinical recommendations.
abstract: Chondroitin sulfate (CS) is recommended as a therapeutic intervention in the multimodal approach of osteoarthritis (OA) management. CS has been studied extensively to describe its pharmacology (pharmacokinetic, in vitro and in vivo effects) and its clinical efficacy. Various results have been reported depending on the system of evaluation (model, dosage and duration) and the source of CS (origin and quality). The purpose of this review was to gather most of the available information about CS and to discuss its potency in OA management.
authors.affiliation: Bone and Cartilage Research Unit, Institute of Pathology, level 5, CHU Sart-Tilman, 4000 Liège, Belgium.
authors.forename: Yves
authors.initials: Y
authors.lastname: Henrotin
authors.forename: Mariane
authors.initials: M
authors.lastname: Mathy
authors.forename: Christelle
authors.initials: C
authors.lastname: Sanchez
authors.forename: Cecile
authors.initials: C
authors.lastname: Lambert