title: C-H bond functionalization: emerging synthetic tools for natural products and pharmaceuticals.
abstract: The direct functionalization of C-H bonds in organic compounds has recently emerged as a powerful and ideal method for the formation of carbon-carbon and carbon-heteroatom bonds. This Review provides an overview of C-H bond functionalization strategies for the rapid synthesis of biologically active compounds such as natural products and pharmaceutical targets.
authors.affiliation: Department of Chemistry, Graduate School of Science, Nagoya University, Chikusa, Nagoya, Japan. junichiro@chem.nagoya-u.ac.jp
authors.forename: Junichiro
authors.initials: J
authors.lastname: Yamaguchi
authors.forename: Atsushi D
authors.initials: AD
authors.lastname: Yamaguchi
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Itami
mesh_terms: D000478:Alkylation; D001688:Biological Products / Q000138:chemical synthesis / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry; D007097:Imines / Q000737:chemistry; D008670:Metals / Q000737:chemistry; D008697:Methane / Q000031:analogs & derivatives / Q000737:chemistry; D004364:Pharmaceutical Preparations / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001688:Biological Products; D007097:Imines; D008670:Metals; D004364:Pharmaceutical Preparations; C030011:carbene; D002244:Carbon; D006859:Hydrogen; D008697:Methane