title: Colonization pressure and risk factors for acquisition of imipenem-resistant Acinetobacter baumannii in a medical surgical intensive care unit in Brazil.
abstract: We studied a nonconcurrent cohort of 582 patients admitted to a medical-surgical intensive care unit. Use of antimicrobials (imipenem and metronidazole) was a risk factor for acquisition of imipenem-resistant Acinetobacter baumannii only for the subcohort of patients admitted in months in which colonization pressure was lower than the median value.
authors.affiliation: Department of Tropical Diseases, Faculdade de Medicina de Botucatu, UNESP-Univ Estadual Paulista, Botucatu, Brazil. cmfortaleza@uol.com.br
authors.forename: Carlos Magno
authors.initials: CM
authors.lastname: Castelo Branco Fortaleza
authors.forename: Fernanda
authors.initials: F
authors.lastname: Moreira de Freitas
authors.forename: Gerhard
authors.initials: G
authors.lastname: da Paz Lauterbach
mesh_terms: D000151:Acinetobacter Infections / Q000453:epidemiology* / Q000382:microbiology*; D040981:Acinetobacter baumannii / Q000187:drug effects* / Q000302:isolation & purification; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001938:Brazil / Q000453:epidemiology; D015331:Cohort Studies; D003422:Critical Care; D006801:Humans; D015378:Imipenem / Q000494:pharmacology* / Q000627:therapeutic use; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents; D015378:Imipenem