title: Central retinal vein occlusion treated with Ozurdex: a case report and review of literature.
abstract: OBJECTIVE
  To describe the retinal changes occurring after Ozurdex(®) (Ozurdex, Allergan, Inc., Irvine, CA) injection and peripheral laser treatment in a case of central retinal vein occlusion (CRVO).
  
  
  METHODS
  A 51-year-old Caucasian man with massive retinal edema (926 μm) and hand motion visual acuity due to severe CRVO was treated early with Ozurdex intravitreal injection. Detailed monthly follow-up examinations showed complete resorption of the edema (253 μm) after 2 months and a 20/32 visual outcome after 3 months. The patient subsequently developed peripheral retinal ischemia accompanied by recurrence of small retinal cystoid spaces (295 μm); therefore, he underwent an associated laser treatment on the involved peripheral retina, which led to a recovery in retinal thickness (280 μm). His visual acuity remained stable at 20/32.
  
  
  CONCLUSIONS
  Early Ozurdex injection in association with late laser photocoagulation was effective in the resorption of CRVO macular edema and in restoring reasonably good visual acuity.
authors.affiliation: Eye Clinic, University of Brescia, Brescia, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Semeraro
authors.forename: Andrea
authors.initials: A
authors.lastname: Russo
authors.forename: Paola
authors.initials: P
authors.lastname: Danzi
authors.forename: Ciro
authors.initials: C
authors.lastname: Costagliola
mesh_terms: D003131:Combined Modality Therapy; D003907:Dexamethasone / Q000008:administration & dosage / Q000627:therapeutic use*; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D058449:Intravitreal Injections; D017075:Laser Coagulation / Q000379:methods*; D008269:Macular Edema / Q000209:etiology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012170:Retinal Vein Occlusion / Q000473:pathology / Q000628:therapy*; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome; D014792:Visual Acuity / Q000187:drug effects
chemical_list: D005938:Glucocorticoids; D003907:Dexamethasone