title: Clinical and microbiological characterization of Staphylococcus lugdunensis isolates obtained from clinical specimens in a hospital in China.
abstract: BACKGROUND
  Several reports have associated Staphylococcus lugdunensis with the incidence of severe infection in humans; however, the frequency and prevalence of this microorganism and thus the propensity of its antimicrobial drug resistance is unknown in China. The objective of the current study was to determine the prevalence of Staphylococcus lugdunensis among six hundred and seventy non-replicate coagulase negative Staphylococcus (CoNS) isolates collected in a 12-month period from clinical specimens in the General Hospital of the People's Liberation Army in Beijing, China.
  
  
  RESULTS
  Five (0.7%) of the 670 isolates of CoNS were identified as S. lugdunensis. Whereas three isolates were resistant to erythromycin, clindamycin, and penicillin and carried the ermC gene and a fourth one was resistant to cefoxitin and penicillin and carried the mecA gene, one isolate was not resistant to any of the tested antimicrobials. Pulse field gel electrophoretic analysis did not reveal widespread epidemiological diversity of the different isolates.
  
  
  CONCLUSIONS
  Hence, even though S. lugdunensis may be yet unrecognized and undefined in China, it still might be the infrequent cause of infection and profound multi-drug resistance in the same population.
authors.affiliation: Department of Clinical Microbiology, General Hospital of The People's Liberation Army, Hai Dian District, Beijing 100853, China.
authors.forename: Chaojun
authors.initials: C
authors.lastname: Liu
authors.forename: Dingxia
authors.initials: D
authors.lastname: Shen
authors.forename: Jing
authors.initials: J
authors.lastname: Guo
authors.forename: Kaifei
authors.initials: K
authors.lastname: Wang
authors.forename: Huan
authors.initials: H
authors.lastname: Wang
authors.forename: Zhongqiang
authors.initials: Z
authors.lastname: Yan
authors.forename: Rong
authors.initials: R
authors.lastname: Chen
authors.forename: Liyan
authors.initials: L
authors.lastname: Ye
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002681:China / Q000453:epidemiology; D016000:Cluster Analysis; D024881:Drug Resistance, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D014644:Genetic Variation; D005838:Genotype; D006772:Hospitals, Military; D006801:Humans; D008297:Male; D008875:Middle Aged; D058889:Molecular Typing; D015995:Prevalence; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology* / Q000473:pathology; D057787:Staphylococcus lugdunensis / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents