title: Exhaled breath condensate pH assays.
abstract: Airway pH is central to the physiologic function and cellular biology of the airway. The causes of airway acidification include (1) hypopharyngeal gastric acid reflux with or without aspiration through the vocal cords, (2) inhalation of acid fog or gas (such as chlorine), and (3) intrinsic airway acidification caused by altered airway pH homeostasis in infectious and inflammatory disease processes. The recognition that relevant airway pH deviations occur in lung diseases is opening doors to new simple and inexpensive therapies. This recognition has resulted partly from the ability to use exhaled breath condensate as a window on airway acid-base balance.
authors.affiliation: Adult Health and Nursing System, Virginia Commonwealth University, Richmond, 23298-0567, USA.
authors.forename: Michael D
authors.initials: MD
authors.lastname: Davis
authors.forename: John
authors.initials: J
authors.lastname: Hunt
mesh_terms: D001944:Breath Tests / Q000379:methods*; D002245:Carbon Dioxide / Q000737:chemistry; D045853:Exhalation; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008171:Lung Diseases / Q000175:diagnosis / Q000378:metabolism; D012016:Reference Values; D015203:Reproducibility of Results
chemical_list: D002245:Carbon Dioxide