title: Early embryonic morphology sonographically assessed and its correlation with yolk sac in missed abortion.
abstract: OBJECTIVE
  To provide additional information about embryo morphology sonographic assessment and its correlation with yolk sac.
  
  
  METHODS
  A systematic study in 200 consecutive cases of missed abortion <10 weeks diagnosed by transvaginal ultrasound.
  
  
  RESULTS
  In 104 gestations of embryos with morphological abnormalities, 88 (84.6 %) were at least 1 week smaller than expected for gestational age and 16 (15.4 %) were the expected size. From 32 normal morphologic embryos, 7 (21.9 %) were at least 1 week smaller than expected for gestational age, and 25 (78.1 %) were the expected size (p < 0.005). Normal morphologic embryos are linked more frequently with normal yolk sac (62.5 %). Findings in anembryonic gestations (GD1) included an absent yolk sac (46.9 %) and a cystic yolk sac (25 %). Likewise, findings in GD2-3 embryos included more frequently a cystic yolk sac (42.9 %) and an absent yolk sac (32.5 %). GD4 embryos are associated with an echogenic yolk sac (40 %), a relatively small-hypoplastic- (40 %) and a relatively large-cystic- (20 %). In DI embryos, yolk sac appears cystic (62.5 %) or echogenic (37.5 %).
  
  
  CONCLUSIONS
  Our study proves the correlation between morphology of conceptuses and yolk sac appearance in cases of missed abortion.
authors.affiliation: Departamento de Obstetricia y Ginecología, Facultad de Medicina, Universidad de Granada, Avda. Madrid s/n, 18014 Granada, Spain.
authors.forename: Alberto
authors.initials: A
authors.lastname: Salamanca
authors.forename: Purificación
authors.initials: P
authors.lastname: Fernández-Salmerón
authors.forename: Estanislao
authors.initials: E
authors.lastname: Beltrán
authors.forename: Nicolás
authors.initials: N
authors.lastname: Mendoza
authors.forename: Jesús
authors.initials: J
authors.lastname: Florido
authors.forename: Juan
authors.initials: J
authors.lastname: Mozas
mesh_terms: D000030:Abortion, Missed / Q000000981:diagnostic imaging*; D004622:Embryo, Mammalian / Q000002:abnormalities / Q000000981:diagnostic imaging*; D005260:Female; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D016216:Ultrasonography, Prenatal; D015017:Yolk Sac / Q000002:abnormalities / Q000000981:diagnostic imaging*