title: [Preliminary study in glycyrrhizin content and its influencing factors of wild and cultivated in different region of China].
abstract: OBJECTIVE
  In order to understand the glycyrrhizin content range in the wild and cultivated Glycyrrhiza uralensis in China and to find the related influencing factors of glycyrrhizin content.
  
  
  METHODS
  The glycyrrhizin content of 165 wild and 1 013 cultivated G. uralensis samples from 37 countries in 9 provinces was determined by HPLC, and the effects of the producing region, medicinal parts, cultivation years, soil type and texture on the glycyrrhizin content were analyzed.
  
  
  CONCLUSIONS
  The average glycyrrhizin content was (4.43 +/- 1.32)% in the wild G. uralensis population, and (1.51 +/- 0.49)% in the cultivated and the glycyrrhizin content in the cultivated was less than the minimum sandards in the Chinese Pharmacopoeia. The glycyrrhizin content was significant different in the wild and cultivated G. uralensis in different producing regions, respectively. The glycyrrhizin content in roots and rhizome of the wild G. uralensis had no significant difference, it had no significant difference in the cultivated G. uralensis from 1 to 4 years and it increased rapidly after 5 years, and the effects of the soil types and texture on it were significant.
authors.affiliation: School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 100102, China. wsl7491@126.com
authors.forename: Shengli
authors.initials: S
authors.lastname: Wei
authors.forename: Wenquan
authors.initials: W
authors.lastname: Wang
authors.forename: Jiyong
authors.initials: J
authors.lastname: Wang
authors.forename: Zhirong
authors.initials: Z
authors.lastname: Sun
authors.forename: Chunsheng
authors.initials: C
authors.lastname: Liu
authors.forename: Hai
authors.initials: H
authors.lastname: Wang
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Yang
authors.forename: Baocai
authors.initials: B
authors.lastname: Wu
mesh_terms: D002681:China; D029882:Glycyrrhiza uralensis / Q000737:chemistry* / Q000254:growth & development; D019695:Glycyrrhizic Acid / Q000032:analysis*
chemical_list: D019695:Glycyrrhizic Acid