title: Acute and chronic toxic effects of bisphenol A on Chlorella pyrenoidosa and Scenedesmus obliquus.
abstract: The acute and chronic toxic effects of Bisphenol A (BPA) on Chlorella pyrenoidosa (C. pyrenoidosa) and Scenedesmus obliquus (S. obliquus) were not well understood. The indoor experiments were carried out to observe and analyze the BPA-induced changes. Results of the observations showed that in acute tests BPA could significantly inhibit the growth of both algae, whereas chronic exposure hardly displayed similar trend. Superoxide dismutase (SOD) and Catalase (CAT) activities of both algae were promoted in all the treatments. Chlorophyll a synthesis of the two algae exhibited similar inhibitory trend in short-term treatments, and in chronic tests C. pyrenoidosa hardly resulted in visible influence, whereas in contrast, dose-dependent inhibitory effects of S. obliquus could be clearly observed. The experimental results indicated that the growth and Chlorophyll a syntheses of S.obliquus were more sensitive in response to BPA than that of C. pyrenoidosa, whereas for SOD andCAT activities, C. pyrenoidosa was more susceptible. This research provides a basic understanding of BPA toxicity to aquatic organisms.
authors.affiliation: State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, East China University of Science and Technology, Shanghai 200237, People's Republic of China; School of Resource and Environmental Engineering, East China University of Science and Technology, Shanghai 200237, People's Republic of China; Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science and Technology, Shanghai 200237, People's Republic of China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Bang
authors.initials: B
authors.lastname: Xiong
authors.forename: Wen-Fang
authors.initials: WF
authors.lastname: Sun
authors.forename: Shuai
authors.initials: S
authors.lastname: An
authors.forename: Kuang-Fei
authors.initials: KF
authors.lastname: Lin
authors.forename: Mei-Jin
authors.initials: MJ
authors.lastname: Guo
authors.forename: Xin-Hong
authors.initials: XH
authors.lastname: Cui
mesh_terms: D001559:Benzhydryl Compounds / Q000633:toxicity*; D002374:Catalase / Q000378:metabolism; D002708:Chlorella / Q000187:drug effects* / Q000254:growth & development; D002734:Chlorophyll / Q000032:analysis; D000077194:Chlorophyll A; D004305:Dose-Response Relationship, Drug; D010636:Phenols / Q000633:toxicity*; D044444:Scenedesmus / Q000187:drug effects* / Q000254:growth & development; D013482:Superoxide Dismutase / Q000378:metabolism; D023382:Toxicity Tests, Acute; D036401:Toxicity Tests, Chronic; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D002374:Catalase; D002734:Chlorophyll; D000077194:Chlorophyll A; D010636:Phenols; D013482:Superoxide Dismutase; C006780:bisphenol A; D000098826:Bisphenol A Compounds