title: Effects of prothrombotic markers and non-O blood group in maternal venous thromboembolism during pregnancy and postpartum.
abstract: Our aim was to assess thrombophilic risk factors and the non-O blood group as contributors to the development of venous thromboembolism during pregnancy and the postpartum period. A total of 199 women underwent blood typing and an extensive thombophilia screening. Factor V Leiden, FII G20210A, protein C deficiency and non-O blood group were significantly associated with venous thromboembolism during pregnancy and postpartum period. A known thrombophilic factor may have consequences for future pregnancies and could have implications for clinical practice. For this reason, women with a history of thromboembolism should be screened for thrombophilia. The non-O blood group could also have an important influence, especially when concomitant with another prothrombotic risk factor mainly pregnancy and thrombophilia.
authors.affiliation: Unit of Molecular Biology, Department of Hematology, Military Hospital, Tunis, Tunisia. gksarrah@yahoo.fr
authors.forename: Sarra
authors.initials: S
authors.lastname: Klai
authors.forename: Najiba
authors.initials: N
authors.lastname: Fekih-Mrissa
authors.forename: Raja B
authors.initials: RB
authors.lastname: Sassi
authors.forename: Ridha
authors.initials: R
authors.lastname: Mrissa
authors.forename: Radhouen
authors.initials: R
authors.lastname: Rachdi
authors.forename: Nasredine
authors.initials: N
authors.lastname: Gritli
mesh_terms: D000328:Adult; D001789:Blood Group Antigens / Q000097:blood*; D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D005838:Genotype; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood*; D012307:Risk Factors; D054556:Venous Thromboembolism / Q000097:blood*; D055815:Young Adult
chemical_list: D001789:Blood Group Antigens