title: Bobble-head doll syndrome: therapeutic outcome and long-term follow-up in four children.
abstract: Bobble-head doll syndrome (BHDS) is a complex syndrome with the dominant symptom of repetitive anteroposterior head movement. Only 57 patients are quoted in the literature. The etiology of this syndrome remains unknown and no standard treatment has yet been established. We hereby report four cases treated at our department. All the patients presented a psychomotor retardation due to an obstructive hydrocephalus. All the patients were treated using neuroendoscopic techniques: two with ventriculocystostomy, and two with ventriculocystocisternostomy. Cyst decompression was achieved in all four cases and clinical recovery was evident in three of the four patients observed. After surgery, BHDS persisted longer the more the subsequent treatment was delayed. In this article, we provide a concise overview of the theories of pathogenesis, presentation, and management of this syndrome. Based on our own experience, we state that the method of choice should be the neuroendoscopy and this must be performed promptly after diagnosis is made.
authors.affiliation: International Clinical Research Center, St. Annes´s University Hospital Brno, Brno, Czech Republic. helena_guerreiro@hotmail.com
authors.forename: Helena
authors.initials: H
authors.lastname: Guerreiro
authors.forename: Ales
authors.initials: A
authors.lastname: Vlasak
authors.forename: Daniel
authors.initials: D
authors.lastname: Horinek
authors.forename: Michal
authors.initials: M
authors.lastname: Tichy
authors.forename: Jiri
authors.initials: J
authors.lastname: Lisy
authors.forename: Petr
authors.initials: P
authors.lastname: Vanek
authors.forename: Petr
authors.initials: P
authors.lastname: Liby
authors.forename: David
authors.initials: D
authors.lastname: Hoza
authors.forename: Vladimir
authors.initials: V
authors.lastname: Beneš
authors.forename: Christopher
authors.initials: C
authors.lastname: Nimsky
mesh_terms: D016080:Arachnoid Cysts / Q000150:complications / Q000601:surgery*; D002648:Child; D020820:Dyskinesias / Q000150:complications / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D019416:Head Movements / Q000502:physiology; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000601:surgery*; D044583:Neuroendoscopy / Q000379:methods; D013577:Syndrome; D020542:Third Ventricle / Q000002:abnormalities / Q000601:surgery; D016896:Treatment Outcome