title: [A contact electroimpulse impact on the ureteral and bladder wall of mature dogs: a 1-year results of a morphological prospective study].
abstract: The aim of the study was investigation of morphological changes in the urinary bladder and ureteral wall of dogs in response to contact electroimpulse impact (CEII); to develop recommendations for utilization of contact electroimpulse lithotripsy in humans. Effects of single-impulse CEII on the bladder and ureteral mucosa produced by an electroimpulse lithotripter were studied in 23 mature mongrel dogs. The morphological material was studied immediately after the impact, 1, 6, 14 days and 1, 3, 6 and 12 months after it. The 0.1-0.7 J electroimpulse impact resulted in fragmentary epithelial necrosis and aceptic inflammation within a muscular layer. An enhanced to 0.8 J impact caused local damage to all layers of the wall including adventitium while a 0.9-1 J impact caused ureteral perforation in 3 cases. Duration of morphological rehabilitation depended on the impact power and was optimal for 0.1-0.5 J impulses with complete mucosal repair to day 14 and complete morphological rehabilitation to month 6 after the procedure. In power 0.6-1 J mucosal recovery increased to 1 month while complete formation of the connective tissue finished after 1 year. None cases of development of ureteral strictures after CEII was observed in follow-up for 1 year.
authors.forename: A V
authors.initials: AV
authors.lastname: Gudkov
authors.forename: V S
authors.initials: VS
authors.lastname: Boshchenko
authors.forename: A V
authors.initials: AV
authors.lastname: Arsen'ev
authors.forename: V V
authors.initials: VV
authors.lastname: Nedosekov
authors.forename: V Ia
authors.initials: VIa
authors.lastname: Afonin
mesh_terms: D000818:Animals; D004285:Dogs; D004599:Electric Stimulation Therapy; D005260:Female; D008297:Male; D014521:Urethra / Q000473:pathology* / Q000503:physiopathology*; D001743:Urinary Bladder / Q000473:pathology* / Q000503:physiopathology*