title: One-pot cascade leading to direct α-imidation of ketones by a combination of N-bromosuccinimide and 1,8-diazabicyclo[5.4.1]undec-7-ene.
abstract: A one-pot cascade transformation of ketones into α-imidoketones has been developed, in which N-bromosuccinimide (NBS) provides both electrophilic bromine and nucleophilic nitrogen sources, and diazabicyclo[5.4.1]undec-7-ene (DBU) functions as a base and a nucleophilic promoter for the activation of NBS. α-Bromination is supposed as the key step in the process, which takes place between more electrophilic bromide active species and enolates.
authors.affiliation: Department of Chemistry, Northeast Normal University, Changchun 130024, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Wei
authors.forename: Shaoxia
authors.initials: S
authors.lastname: Lin
authors.forename: Fushun
authors.initials: F
authors.lastname: Liang