title: Buruli ulcer disease in travelers and differentiation of Mycobacterium ulcerans strains from northern Australia.
abstract: Buruli ulcer (BU) is a necrotizing infection of skin and soft tissue caused by Mycobacterium ulcerans. In Australia, most cases of BU are linked to temperate, coastal Victoria and tropical, northern Queensland, and strains from these regions are distinguishable by variable-number tandem repeat (VNTR) typing. We present an epidemiological investigation of five patients found to have been infected during interstate travel and describe two nucleotide polymorphisms that differentiate M. ulcerans strains from northern Australia.
authors.affiliation: Victorian Infectious Diseases Reference Laboratory, North Melbourne, Victoria, Australia.
authors.forename: Caroline J
authors.initials: CJ
authors.lastname: Lavender
authors.forename: Maria
authors.initials: M
authors.lastname: Globan
authors.forename: Paul D R
authors.initials: PD
authors.lastname: Johnson
authors.forename: Patrick G P
authors.initials: PG
authors.lastname: Charles
authors.forename: Grant A
authors.initials: GA
authors.lastname: Jenkin
authors.forename: Niladri
authors.initials: N
authors.lastname: Ghosh
authors.forename: Benjamin M
authors.initials: BM
authors.lastname: Clark
authors.forename: Marianne
authors.initials: M
authors.lastname: Martinello
authors.forename: Janet A M
authors.initials: JA
authors.lastname: Fyfe
mesh_terms: D000328:Adult; D000368:Aged; D001315:Australia / Q000453:epidemiology; D054312:Buruli Ulcer / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology; D016000:Cluster Analysis; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D058889:Molecular Typing; D019911:Mycobacterium ulcerans / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D010802:Phylogeny; D011110:Polymorphism, Genetic; D014195:Travel