title: The cytogenetic effects of the aqueous extracts of migratory locust (Locusta migratoria L.) in vitro.
abstract: One of the useful and most commonly cultivated commercially species, migratory locust (Locusta migratoria; Orthoptera), was investigated in light of genotoxic damage potentials. For this aim, we evaluated the genotoxic potentials of water soluble extracts of L. migratoria on cultured human blood cells. The micronucleus, sister chromatid exchange and structural chromosome aberration assays were applied to assess DNA and chromosomal damage produced by aqueous extracts in vitro. The extracts were added to the cultures at different concentrations ranging from 0 to 1000 mg/L. Our results indicated that these extracts did not exhibit genotoxicity at tested concentrations. We conclude that this in vitro approach for biomonitoring genotoxicity assessment is useful for comparing the potential health risks of edible insects.
authors.affiliation: 1Department of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, Erzurum, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Turkez
authors.forename: Umit
authors.initials: U
authors.lastname: Incekara
authors.forename: Adem
authors.initials: A
authors.lastname: Güner
authors.forename: Elanur
authors.initials: E
authors.lastname: Aydın
authors.forename: Ebubekir
authors.initials: E
authors.lastname: Dirican
authors.forename: Başak
authors.initials: B
authors.lastname: Togar
mesh_terms: D000818:Animals; D001688:Biological Products / Q000633:toxicity*; D002869:Chromosome Aberrations / Q000139:chemically induced*; D004249:DNA Damage / Q000187:drug effects*; D006801:Humans; D048188:Locusta migratoria / Q000235:genetics*; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity*; D012854:Sister Chromatid Exchange / Q000187:drug effects
chemical_list: D001688:Biological Products; D009153:Mutagens