title: Significant improvement of chronic pain by Pregabalin after thoracotomy: report of four cases.
abstract: Unfortunately, many patients may have persistent pain lasting for many months, or even years, following thoracic surgery. No effective treatment has so far been established for chronic pain after thoracotomy. There are no reports of treatment involving Pregabalin for pain after thoracic surgery. This study reports four cases that showed significant improvement with Pregabalin in late-onset (notified during an office visit after discharge) nocturnal insomnia and in stress-induced ulcers caused by intercostal neuralgia after thoracotomy.
authors.affiliation: Department of Surgery, Teikyo University School of Medicine, 2-11-1 Kaga Itabashi-ku, Tokyo, 173-8605, Japan. matsutani1970@yahoo.co.jp
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Matsutani
authors.forename: Masafumi
authors.initials: M
authors.lastname: Kawamura
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery; D000368:Aged; D000700:Analgesics / Q000008:administration & dosage*; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D059350:Chronic Pain / Q000188:drug therapy*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007367:Intercostal Nerves; D008175:Lung Neoplasms / Q000601:surgery; D008297:Male; D010149:Postoperative Pain / Q000188:drug therapy*; D011013:Pneumonectomy; D000069583:Pregabalin; D013908:Thoracotomy; D016896:Treatment Outcome; D005680:gamma-Aminobutyric Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*
chemical_list: D000700:Analgesics; D000069583:Pregabalin; D005680:gamma-Aminobutyric Acid