title: A soy-based supplement alters energy metabolism but not the exercise-induced stress response.
abstract: OBJECTIVE
  To determine the changes in endurance capacity as well as in metabolic, hormonal and inflammatory markers induced by endurance training combined with a soy,protein based supplement.
  
  
  METHODS
  Randomized controlled study consisting of moderate endurance training without (GO) or with (G1) a soy protein based supplement.
  
  
  METHODS
  Two groups of 15 subjects (10 males and 5 females in each group): healthy sports students aged 23.6 +/- 1.9 years.
  
  
  METHODS
  Body composition (body mass (BM), body density (BD) by air displacement) and physical fitness (determined by treadmill ergometry) were measured at baseline and after 6 weeks of the intervention; changes in circulating metabolic and hormonal parameters (glucose, lactate, urea, uric acid, ammonia, cortisol, insulin, IGF-1), and exercise-induced stress and inflammatory markers (CK, LDH, myoglobin, hs-CRP, IL-6, IL-10, blood cell counts) were determined after the intervention period in afield test (11.5 km running on hilly ground).
  
  
  RESULTS
  30 participants completed the 6-week study; 28 students were able to perform the field test. No significant changes in BM and BD were noted after intervention with only slight increases in running performance and maximum aerobic capacity in the total group (2%, p=0.016). Subjects in the G1 group showed significant improvements in running velocity and lower lactate values following the intervention (-12%, p=0,003). In addition, the G1 group showed significantly lower differences in the exercise-induced increase of metabolic parameters (triglycerides, uric acid) and insulin in the post-exercise recovery period.
  
  
  CONCLUSIONS
  Our data suggest that moderate endurance training in combination with a soy-based protein supplement improves aerobic energy supply and metabolic function in healthy sports students, even without changes in body composition and without changes in the exercise-induced stress and inflammatory reaction.
authors.affiliation: Universitätsklinikum Freiburg, Abt. Rehabilitative und Präventive Sportmedizin Universität Freiburg, Institut für Sport und Sportwissenschaft, Bereich Ernährung.
authors.forename: Aloys
authors.initials: A
authors.lastname: Berg
authors.forename: Denise
authors.initials: D
authors.lastname: Schaffner
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Pohlmann
authors.forename: Manfred W
authors.initials: MW
authors.lastname: Baumstark
authors.forename: Peter
authors.initials: P
authors.lastname: Deibert
authors.forename: Daniel
authors.initials: D
authors.lastname: König
authors.forename: Albert
authors.initials: A
authors.lastname: Gollhofer
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001772:Blood Cell Count; D001823:Body Composition / Q000502:physiology; D002241:Carbohydrates / Q000097:blood; D016207:Cytokines / Q000097:blood; D019587:Dietary Supplements; D004734:Energy Metabolism / Q000187:drug effects*; D015444:Exercise / Q000502:physiology*; D005260:Female; D006728:Hormones / Q000097:blood; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D009211:Myoglobin / Q000097:blood; D010809:Physical Fitness / Q000502:physiology; D030262:Soybean Proteins / Q000008:administration & dosage*; D013177:Sports; D013312:Stress, Physiological / Q000187:drug effects*
chemical_list: D015415:Biomarkers; D002241:Carbohydrates; D016207:Cytokines; D006728:Hormones; D008055:Lipids; D009211:Myoglobin; D030262:Soybean Proteins