title: [Combined therapy of patients with recurring anogenital herpes infection].
abstract: Up-to-date conceptions of etiology and epidemiology of anogenital herpetic infection are described. The main mechanisms of immunological shifts in subjects with anogenital Herpes infection are discussed. The efficacy and safety of cycloferon in the combined treatment of patients with recurring anogenital herptic infection were estimated. The clinical efficacy of the combined therapy (acyclovir in a dose of 200 mg 5 times a day for 5 days + cycloferon liniment applied topically on the eruptions twice a day for 5 days) was 85% or 25% higher vs. the control.
authors.forename: M R
authors.initials: MR
authors.lastname: Rakhmatulina
mesh_terms: D000166:Acridines / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D000212:Acyclovir / Q000009:adverse effects / Q000627:therapeutic use*; D000287:Administration, Topical; D000998:Antiviral Agents / Q000009:adverse effects / Q000627:therapeutic use; D006558:Herpes Genitalis / Q000188:drug therapy; D006561:Herpes Simplex / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D012008:Recurrence; D012749:Sexually Transmitted Diseases / Q000188:drug therapy; D013997:Time Factors
chemical_list: D000166:Acridines; D000998:Antiviral Agents; D000212:Acyclovir; C026430:10-carboxymethyl-9-acridanone