title: Cerebrovascular assessment for the risk prediction of Alzheimer's disease.
abstract: Increasing evidence is emerging that vascular disease and its risk factors play a role in the development of Alzheimer's disease (AD) and affect the probability of an adverse outcome. The aims of this review are to explore the relationship between vascular risk factors and AD and to discuss the potential use of vascular markers in the clinical approach to cognitive impairment. Moreover, we present evidence about the potential use of ultrasonographic and neuroradiologic markers of cognitive impairment in order to establish possible treatment strategies in subjects with a clinical profile at risk of developing AD.
authors.affiliation: Neurological Clinic, Marche Polytechnic University, Ancona, Italy. m.silvestrini@univpm.it
authors.forename: Mauro
authors.initials: M
authors.lastname: Silvestrini
authors.forename: Giovanna
authors.initials: G
authors.lastname: Viticchi
authors.forename: Claudia
authors.initials: C
authors.lastname: Altamura
authors.forename: Simona
authors.initials: S
authors.lastname: Luzzi
authors.forename: Clotilde
authors.initials: C
authors.lastname: Balucani
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Vernieri
mesh_terms: D000544:Alzheimer Disease / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology*; D000818:Animals; D002560:Cerebrovascular Circulation / Q000502:physiology*; D003072:Cognition Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D011237:Predictive Value of Tests; D012307:Risk Factors