title: Newly discovered quick, non-invasive screening method of bone marrow malignancies including various leukemias, Hodgkin's lymphoma, non-Hodgkin's lymphoma, & multiple myeloma by abnormality of small rectangular area within bone marrow organ representation areas of the face.
abstract: Diagnoses of bone marrow associated malignancies such as Acute & Chronic Lymphocytic Leukemia, Acute & Chronic Myelogenous (Myeloid) Leukemia, Hodgkin's Lymphoma & Non-Hodgkin's Lymphoma, and Multiple Myeloma are often missed without a blood test. However, in 2008, Omura Y reported several newly discovered organ representation areas that exist between the lower end of the eyebrows and upper end of the upper eyelid. This space was divided into 5 organ representation areas. The first space (more than 1/4 of entire space) near the side of the face (temple) is the bone marrow representation area (BMRA). Therefore, we examined the bone marrow representation areas non-invasively using the Bi-Digital O-Ring Test (BDORT). When the small rectangular shaped part of the BMRA is strong negative (-) with more than -2, often there is a malignancy associated with bone marrow. In this area, we found 1) Integrin alpha5beta1 & Oncogen C-fos Ab2 increased very significantly between 125-300 ng BDORT units; 2) very high Chrysotile Asbestos (0.11-0.14 mg); 3) markedly reduced Acetylcholine of less than 1 ng; 4) significantly reduced telomere of less than 1 yg (= 10(-24) g); and 5) Increased 8-OH-dG (often more than 5 ng). Once the abnormal small rectangular area is localized by BDORT, by detecting the specific microscope slide which produces EMF (electromagnetic field) resonance, one can diagnose these malignancies non-invasively in about 10 minutes. When a subject has any one of the above 7 types of bone marrow associated malignancies, the 5 aforementioned abnormal parameters can be detected. When Acetylcholine is markedly reduced to 0.25 ng or less, 8-OH-dG is 10 ng or higher, and Sirtuin 1 (one of the 7 mammalian longevity genes products) in both the Hippocampus and the body is 0.025 pg or less, most of the patients have a very poor prognosis. However, we found that increasing normal cell telomere & longevity gene product Sirtuin 1 can often improve both pathology & prognosis. All measurements are in BDORT units (the weight required to produce maximum EMF resonance).
authors.affiliation: Heart Disease Research Foundation. icaet@yahoo.com
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Omura
authors.forename: Brian
authors.initials: B
authors.lastname: O'Young
authors.forename: Marilyn
authors.initials: M
authors.lastname: Jones
authors.forename: Abdalla
authors.initials: A
authors.lastname: Nihrane
authors.forename: Harsha
authors.initials: H
authors.lastname: Duvvi
authors.forename: Kamila
authors.initials: K
authors.lastname: Paluch
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Shimotsuura
authors.forename: Motomu
authors.initials: M
authors.lastname: Ohki
mesh_terms: D000080242:8-Hydroxy-2'-Deoxyguanosine; D000109:Acetylcholine / Q000032:analysis; D000293:Adolescent; D000328:Adult; D000368:Aged; D017632:Asbestos, Serpentine / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003849:Deoxyguanosine / Q000031:analogs & derivatives / Q000032:analysis; D004574:Electromagnetic Fields; D005260:Female; D006689:Hodgkin Disease / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D039081:Integrin alpha5beta1 / Q000032:analysis; D007938:Leukemia / Q000175:diagnosis*; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis*; D016760:Proto-Oncogene Proteins c-fos / Q000032:analysis; D016615:Telomere
chemical_list: D017632:Asbestos, Serpentine; D039081:Integrin alpha5beta1; D016760:Proto-Oncogene Proteins c-fos; D000080242:8-Hydroxy-2'-Deoxyguanosine; D003849:Deoxyguanosine; D000109:Acetylcholine