title: Unsuspected pheochromocytoma of the urinary bladder: reminder of an important clinical lesson.
abstract: Bladder pheochromocytoma creates an extremely rare situation (0.06% of all bladder tumours). We came across a case with a complaint of intermittent episodes of haematuria. Cystoscopy revealed a solid, bluish submucosal growth with increased vascularity. Immediately after taking biopsy, the patient developed a sharp headache, chest heaviness and marked rise in blood pressure. The procedure was abandoned. Later, serum and urinary markers for pheochromocytoma were within normal limits. The histopathology report came out to be pheochromocytoma of the bladder. Later, partial cystectomy was carried out under general anaesthesia and histopathology confirmed the same. Thus, a surgeon/urologist should have a high index of suspicion for bladder pheochromocytoma while dealing with such cases if he comes across the characteristic symptoms of sharp headache, hypertension, palpitation, sweating, fainting or blurring of vision immediately after voiding or during the cystoscopic manipulation of tumour or cystoscopic findings of a submucosal supratrigonal vascular tumour with a bluish hue.
authors.affiliation: Department of Surgery, CSMMU Lucknow, Lucknow, Uttar Pradesh, India. pahwakgmu@yahoo.co.in
authors.forename: Harvinder Singh
authors.initials: HS
authors.lastname: Pahwa
authors.forename: Awanish
authors.initials: A
authors.lastname: Kumar
authors.forename: Rohit
authors.initials: R
authors.lastname: Srivastava
authors.forename: Anurag
authors.initials: A
authors.lastname: Rai
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D015653:Cystectomy; D003558:Cystoscopy; D006261:Headache / Q000209:etiology*; D006417:Hematuria / Q000209:etiology*; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008790:Metoprolol / Q000627:therapeutic use; D009599:Nitroprusside / Q000627:therapeutic use; D010643:Phenoxybenzamine / Q000627:therapeutic use; D010646:Phentolamine / Q000627:therapeutic use; D010673:Pheochromocytoma / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D014554:Urination
chemical_list: D000959:Antihypertensive Agents; D010643:Phenoxybenzamine; D009599:Nitroprusside; D008790:Metoprolol; D010646:Phentolamine