title: Changing epidemiologic patterns of deliberate self poisoning in a rural district of Sri Lanka.
abstract: BACKGROUND
  Acute poisoning is a major public health issue in many parts of the world. The epidemiology and the mortality rate is higher in low and middle income countries, including Sri Lanka. The aim of this study was to provide details about the epidemiology of acute poisoning in a rural Sri Lankan district and to identify the changing patterns and epidemiology of poisoning.
  
  
  METHODS
  A prospective study was conducted from September 2008 to January 2010 in all hospitals with inpatient facilities in Anuradhapura district of North Central Province of Sri Lanka. Acute poisoning data was extracted from patient charts. Selected data were compared to the data collected from a 2005 study in 28 hospitals.
  
  
  RESULTS
  There were 3813 poisoned patients admitted to the hospitals in the Anuradhapura district over 17 months. The annual population incidence was 447 poisoning cases per 100,000 population. The total number of male and female patients was approximately similar, but the age distribution differed by gender. There was a very high incidence of poisoning in females aged 15-19, with an estimated cumulative incidence of 6% over these five years. Although, pesticides are still the most common type of poison, medicinal drug poisonings are now 21% of the total and have increased 1.6 fold since 2005.
  
  
  CONCLUSIONS
  Acute poisoning remains a major public health problem in rural Sri Lanka and pesticide poisoning remains the most important poison. However, cases of medicinal drug poisoning have recently dramatically increased. Youth in these rural communities remain very vulnerable to acute poisoning and the problem is so common that school-based primary prevention programs may be worthwhile.Lalith Senarathna, Shaluka F Jayamanna, Patrick J Kelly, Nick A Buckley,michael J Dibley, Andrew H Dawson. These authors contributed equally to this work.
authors.affiliation: South Asian Clinical Toxicology Research Collaboration, University of Peradeniya, Peradeniya, Sri Lanka. l_senarathna@hotmail.com
authors.forename: Lalith
authors.initials: L
authors.lastname: Senarathna
authors.forename: Shaluka F
authors.initials: SF
authors.lastname: Jayamanna
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Kelly
authors.forename: Nick A
authors.initials: NA
authors.lastname: Buckley
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Dibley
authors.forename: Andrew H
authors.initials: AH
authors.lastname: Dawson
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002219:Carbamates / Q000506:poisoning; D002648:Child; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D062025:Organophosphate Poisoning; D010575:Pesticides / Q000506:poisoning; D010947:Plants, Toxic / Q000506:poisoning; D011041:Poisoning / Q000453:epidemiology* / Q000401:mortality; D011159:Population Surveillance; D055553:Prescription Drugs / Q000506:poisoning; D012424:Rural Population / Q000706:statistics & numerical data*; D016728:Self-Injurious Behavior / Q000453:epidemiology* / Q000401:mortality; D017678:Sex Distribution; D013188:Sri Lanka / Q000453:epidemiology; D031052:Thevetia / Q000506:poisoning
chemical_list: D002219:Carbamates; D010575:Pesticides; D055553:Prescription Drugs