title: ERCP for the treatment of bile leak after partial hepatectomy and fenestration for symptomatic polycystic liver disease.
abstract: OBJECTIVE
  To describe endoscopic treatment of bile leaks in these patients and to identify risk factors in these patients which can predict the development of bile leaks.
  
  
  METHODS
  Retrospective case-control study examining consecutive patients who underwent partial hepatectomy for polycystic liver disease (PLD) and developed a postoperative bile leak managed endoscopically over a ten year period. Each case was matched with two controls with PLD who did not develop a postoperative bile leak.
  
  
  RESULTS
  Ten cases underwent partial hepatectomy with fenestration for symptoms including abdominal distention, pain and nausea. Endoscopic retrograde cholangiopancreatography (ERCP) showed anatomic abnormalities in 1 case. A biliary sphincterotomy was performed in 4 cases. A plastic biliary stent was placed with the proximal end at the site of the leak in 9 cases; in 1 case two stents were placed. The overall success rate of ERCP to manage the leak was 90%. There were no significant differences in age, gender, comorbidities, duration of symptoms, history of previous surgery or type of surgery performed between cases and controls.
  
  
  CONCLUSIONS
  ERCP with stent placement is safe and effective for management of post-hepatectomy bile leak in patients with PLD.
authors.affiliation: Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
authors.forename: Nayantara
authors.initials: N
authors.lastname: Coelho-Prabhu
authors.forename: David M
authors.initials: DM
authors.lastname: Nagorney
authors.forename: Todd H
authors.initials: TH
authors.lastname: Baron
mesh_terms: D000328:Adult; D000368:Aged; D001646:Bile / Q000378:metabolism*; D001659:Biliary Tract / Q000473:pathology; D016022:Case-Control Studies; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects*; D015897:Comorbidity; D003560:Cysts / Q000601:surgery / Q000628:therapy*; D004724:Endoscopy / Q000379:methods; D005260:Female; D005762:Gastroenterology / Q000379:methods; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008107:Liver Diseases / Q000601:surgery / Q000628:therapy*; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D015607:Stents; D016896:Treatment Outcome