title: Preliminary experience of fast-track surgery combined with laparoscopy-assisted radical distal gastrectomy for gastric cancer.
abstract: OBJECTIVE
  The aim of this study was to evaluate the safety and effectiveness of fast-track surgery combined with laparoscopy-assisted radical distal gastrectomy for gastric cancer.
  
  
  METHODS
  Eighty-eight eligible patients were randomly assigned into four groups: (1) fast-track surgery (FTS) + laparoscopy-assisted radical distal gastrectomy (LADG), treated with LADG and FTS treatment; (2) LADG, treated with LADG and traditional treatment; (3) FTS + open distal grastectomy (ODG), treated with ODG and FTS treatment; and (4) ODG, treated with ODG and traditional treatment. The clinical parameters and serum indicators were compared.
  
  
  RESULTS
  Compared with the ODG group, the other three groups had earlier first flatus and shorter postoperative hospital stay (all P <0.01; all P <0.05), especially in the FTS + LADG group. The level of ALB was higher in the FTS + LADG group than in the LADG group at 4 and 7 days after surgery (P <0.05, P <0.01). The level of CRP in the FTS + LADG group was lower than in the FTS+ODG group at 4 and 7 days after surgery (P <0.05, P <0.05). The FTS + ODG group had lowest medical costs.
  
  
  CONCLUSIONS
  Combination of FTS and LADG in gastric cancer is safe, feasible, and efficient and can improve nutritional status, lessen postoperative stress, and accelerate postoperative rehabilitation. Compared with FTS + ODG and LADG, its advantages were limited in short-term follow-up.
authors.affiliation: Department of Gastrointestinal Surgery, Yantai Yuhuangding Hospital Affiliated to Medical College of Qingdao University, No. 20 Yuhuangding East Road, Yantai, Shandong, 264000, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Chen Hu
authors.forename: Li
authors.initials: L
authors.lastname: Xin Jiang
authors.forename: Li
authors.initials: L
authors.lastname: Cai
authors.forename: Hai
authors.initials: H
authors.lastname: Tao Zheng
authors.forename: San
authors.initials: S
authors.lastname: Yuan Hu
authors.forename: Hong
authors.initials: H
authors.lastname: Bing Chen
authors.forename: Guo
authors.initials: G
authors.lastname: Chang Wu
authors.forename: Yi
authors.initials: Y
authors.lastname: Fei Zhang
authors.forename: Zhong
authors.initials: Z
authors.lastname: Chuan Lv
mesh_terms: D000328:Adult; D000368:Aged; D002681:China; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000191:economics / Q000379:methods* / Q000534:rehabilitation; D017721:Hospital Costs / Q000706:statistics & numerical data; D006801:Humans; D010535:Laparoscopy / Q000191:economics / Q000534:rehabilitation; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D019990:Perioperative Care / Q000191:economics / Q000379:methods*; D011446:Prospective Studies; D020127:Recovery of Function; D016037:Single-Blind Method; D013274:Stomach Neoplasms / Q000191:economics / Q000601:surgery*; D016896:Treatment Outcome