title: Antioxidant responses in Phanerochaete chrysosporium exposed to Astrazone Red FBL textile dye.
abstract: Interest in environmental-pollutant-induced oxidative stress and knowledge of the interactions between reactive oxygen species and cellular systems have increased in toxicology and microbial ecology considerably in recent decades. These reactive oxidants are produced by a variety of environmental sources: ionizing radiations, ultraviolet light, redox cycling drugs, hyperoxia, ischemia and redox-active xenobiotics or during metabolism of environmental pollutants, such as heavy metals in mining industries, dyes in wastewater of textile industries, pesticides and polycyclic hydrocarbons, i.e. foreign materials. In this study, the effect of dye on the antioxidative defence system of Phanerochaete chrysosporium was investigated, and we showed the ability of Phanerochaete chrysosporium to antioxidative response and defence system exposed to Astrazone Red FBL. Catalase, glutathione reductase, glutathione s-transferase activities and level of glutathione decreased, depending on the period of growth in each exposure to low and high concentration group (20 and 50 ppm) compared with the control group.
authors.affiliation: Department of General Biology, Science and Art Faculty, Dicle University, Diyarbakır, Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Demirci
authors.forename: Dilek Asma
authors.initials: DA
authors.lastname: Hamamcı
mesh_terms: D001391:Azo Compounds / Q000008:administration & dosage / Q000633:toxicity*; D001673:Biodegradation, Environmental; D002374:Catalase / Q000378:metabolism; D004396:Coloring Agents / Q000008:administration & dosage / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D005656:Fungal Proteins / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D005980:Glutathione Reductase / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000187:drug effects; D020075:Phanerochaete / Q000187:drug effects* / Q000201:enzymology / Q000254:growth & development; D014874:Water Pollutants, Chemical / Q000008:administration & dosage / Q000633:toxicity*
chemical_list: D001391:Azo Compounds; D004396:Coloring Agents; D005656:Fungal Proteins; D014874:Water Pollutants, Chemical; C050846:basic red 46; D002374:Catalase; D005980:Glutathione Reductase; D005982:Glutathione Transferase; D005978:Glutathione