title: Novel imaging chelates for drug discovery.
abstract: The introduction of organic frameworks designed to coordinate metal ions or chelates to medical imaging has allowed for significant breakthroughs in the identification of many disease states. These identified disease states such as cancerous, cardiovascular and neurological, which provide excellent targets for novel drugs, and without the imaging chelates would certainly not have been discovered. In this article we will present a series of novel imaging chelates that have influenced drug discovery.
authors.affiliation: Department of Chemistry, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
authors.forename: Graeme J
authors.initials: GJ
authors.lastname: Stasiuk
authors.forename: Stephen
authors.initials: S
authors.lastname: Faulkner
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Long
mesh_terms: D000818:Animals; D002614:Chelating Agents / Q000737:chemistry*; D003952:Diagnostic Imaging / Q000379:methods*; D055808:Drug Discovery / Q000379:methods*; D006801:Humans; D007477:Ions / Q000737:chemistry; D008670:Metals / Q000737:chemistry
chemical_list: D002614:Chelating Agents; D007477:Ions; D008670:Metals