title: Topiramate-induced refractive change and angle closure glaucoma and its ultrasound bimicroscopy findings.
abstract: Topiramate, a sulpha-based medication used in the treatment of migraine, has been documented as causing choroidal effusions, transient myopia and acute secondary angle closure glaucoma. We would like to report a case demonstrating these adverse effects and underscore the utility of ultrasound biomicroscopy in diagnosis and management.
authors.affiliation: Department of Ophthalmology, Maimonides Medical Center, Brooklyn, New York, USA. eyesitemd@gmail.com
authors.forename: Norman
authors.initials: N
authors.lastname: Saffra
authors.forename: Sanjay N
authors.initials: SN
authors.lastname: Smith
authors.forename: Carly Jane
authors.initials: CJ
authors.lastname: Seidman
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D005632:Fructose / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D015812:Glaucoma, Angle-Closure / Q000139:chemically induced* / Q000000981:diagnostic imaging; D006801:Humans; D007429:Intraocular Pressure; D033401:Microscopy, Acoustic; D008881:Migraine Disorders / Q000188:drug therapy*; D011239:Prednisolone / Q000008:administration & dosage; D000077236:Topiramate; D014786:Vision Disorders / Q000139:chemically induced* / Q000000981:diagnostic imaging
chemical_list: D000927:Anticonvulsants; D000077236:Topiramate; D005632:Fructose; D011239:Prednisolone