title: Breakthrough trichosporonosis in patients receiving echinocandins: case report and literature review.
abstract: Trichosporon species now ranks as the second most common cause of disseminated yeast infections with a high mortality rate. Breakthrough trichosporonosis in patients receiving echinocandins therapy is being recognized recently. We present a case of breakthrough trichosporonosis with acute viral myocarditis while receiving caspofungin therapy. Trichosporon infection should be considered in patients, who have risk factors for invasive fungal infection and develop unexplained clinical manifestations of infection despite treatment with echinocandins.
authors.affiliation: Department of Dermatology, General Hospital of Beijing Military Command, Beijing 100700, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Liao
authors.forename: Thomas
authors.initials: T
authors.lastname: Hartmann
authors.forename: Tao
authors.initials: T
authors.lastname: Zheng
authors.forename: Rong-Ya
authors.initials: RY
authors.lastname: Yang
authors.forename: Jun-Hong
authors.initials: JH
authors.lastname: Ao
authors.forename: Wen-Ling
authors.initials: WL
authors.lastname: Wang
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D000077336:Caspofungin; D054714:Echinocandins / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D055666:Lipopeptides; D016896:Treatment Outcome; D060586:Trichosporonosis / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D000077336:Caspofungin