title: A 12-month clinical evaluation of pit-and-fissure sealants placed with and without etch-and-rinse and self-etch adhesive systems in newly-erupted teeth.
abstract: OBJECTIVE
  The objective of this one-year clinical study was to investigate the effect of two adhesive systems (Adper Single Bond, a two-step etch-and-rinse and Clearfil SE Bond, a two-step self-etch system) on pit-and-fissure sealant retention in newly-erupted teeth. This study compared the success of the sealants in mesial and distopalatal grooves with and without these two adhesive systems.
  
  
  METHODS
  In a clinical trial, 35 children aged 6-8 years undergoing sealant placement were recruited. This one-year clinical study scored 70 mesial and 70 distopalatal sealants of newly-erupted permanent maxillary first molar, with a split-mouth design. All children received sealant alone in one permanent maxillary molar tooth. Children were randomized into two groups. One group received Self-etch (Se) bond plus sealant and the other group received Single Bond plus sealant in another permanent maxillary molar tooth. Clinical evaluation at 3, 6 and 12 months was performed and the retention was studied in terms of the success and failure.
  
  
  RESULTS
  The success rate of sealant in the distopalatal groove, using SeB at 3, 6 and 12 months was 93.3% (95% CI: 68.0, 99.8), 73.3% (95% CI: 44.9, 92.2) and 66.7% (95% CI: 38.4, 88.2), respectively. It was greater than that of the distopalatal groove in SB group with a success rate of 62.5% (95% CI: 35.4, 84.8), 31.3% (95% CI: 11.8, 58.7) and 31.3% (95% CI: 11.8, 58.7), at the three evaluation periods. The success rate of sealant in the mesial groove using SeB was 86.6% (95% CI: 59.5, 98.3), 53.3% (95% CI: 26.6, 78.7) and 53.3% (95% CI: 26.6, 78.7), while this was 100% (95% CI: 79.4, 100.0), 81.3% (95% CI: 54.4, 96.0) and 81.3% (95% CI: 54.4, 96.0) using SB, at 3, 6 and 12-month evaluation periods.
  
  
  CONCLUSIONS
  These results support the use of these two bonding agents in pit-and-fissure sealants under both isolated and contaminated conditions. Further, Se bond seemed to be less sensitive to moisture contamination.
authors.affiliation: Department of Pediatric Dentistry, Dental School, Islamic Azad University Khorasgan Branch, Isfahan, Iran. maryam_karami@yahoo.com
authors.forename: Maryam Karami
authors.initials: MK
authors.lastname: Nogourani
authors.forename: Mohsen
authors.initials: M
authors.lastname: Janghorbani
authors.forename: Parvin
authors.initials: P
authors.lastname: Khadem
authors.forename: Zahra
authors.initials: Z
authors.lastname: Jadidi
authors.forename: Shahriar
authors.initials: S
authors.lastname: Jalali
mesh_terms: D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry / Q000627:therapeutic use; D016009:Chi-Square Distribution; D002648:Child; D001840:Dental Bonding / Q000379:methods*; D003738:Dental Cements / Q000737:chemistry* / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010895:Pit and Fissure Sealants / Q000737:chemistry* / Q000627:therapeutic use; D019279:Resin Cements / Q000737:chemistry / Q000627:therapeutic use; D013499:Surface Properties; D013997:Time Factors; D014078:Tooth Eruption / Q000187:drug effects*; D016896:Treatment Outcome
chemical_list: C438313:Clearfil SE Bond; D003738:Dental Cements; D010895:Pit and Fissure Sealants; D019279:Resin Cements; C115612:single bond; D017438:Bisphenol A-Glycidyl Methacrylate