title: Decarbonylative C-H coupling of azoles and aryl esters: unprecedented nickel catalysis and application to the synthesis of muscoride A.
abstract: A nickel-catalyzed decarbonylative C-H biaryl coupling of azoles and aryl esters is described. The newly developed catalytic system does not require the use of expensive metal catalysts or silver- or copper-based stoichiometric oxidants. We have successfully applied this new C-H arylation reaction to a convergent formal synthesis of muscoride A.
authors.affiliation: Department of Chemistry, Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan.
authors.forename: Kazuma
authors.initials: K
authors.lastname: Amaike
authors.forename: Kei
authors.initials: K
authors.lastname: Muto
authors.forename: Junichiro
authors.initials: J
authors.lastname: Yamaguchi
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Itami
mesh_terms: D001393:Azoles / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D004952:Esters / Q000737:chemistry; D008958:Models, Molecular; D009532:Nickel / Q000737:chemistry*; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001393:Azoles; D004952:Esters; D010080:Oxazoles; D011759:Pyrrolidines; C476225:muscoride A; D009532:Nickel