title: [Giant haemangioma of the liver: diagnosis and treatment].
abstract: A liver haemangioma is a benign, usually small tumour comprised of blood vessels, which is often discovered coincidentally; giant haemangiomas are defined as haemangiomas larger than 5 cm. The differential diagnosis includes other hypervascular tumours, such as hepatocellular adenoma, hepatocellular carcinoma, metastasis of a neuro-endocrine tumour or renal cell carcinoma.- The diagnosis is based on abdominal ultrasonography and can be confirmed by a CT or MR scan. A wait-and-see approach is justified in patients without symptoms or with minimal symptoms, even in the presence of a giant haemangioma. Surgical resection of a giant haemangioma is only necessary when the preoperative diagnosis is inconclusive, or when the haemangioma leads to mechanical symptoms or complications. Extirpation is the only effective form of treatment of the giant haemangioma; enucleation is preferred over partial liver resection. A known complication of a giant haemangioma is the occurrence of disseminated intravascular coagulation, the Kasabach-Merritt syndrome; intervention is then demanded.
authors.affiliation: Academisch Medisch Centrum, Afd. Chirurgie, Amsterdam, the Netherlands. l.t.hoekstra@amc.uva.nl
authors.forename: Lisette T
authors.initials: LT
authors.lastname: Hoekstra
authors.forename: Matthanja
authors.initials: M
authors.lastname: Bieze
authors.forename: Deha
authors.initials: D
authors.lastname: Erdogan
authors.forename: Joris J T H
authors.initials: JJ
authors.lastname: Roelofs
authors.forename: Ulrich H W
authors.initials: UH
authors.lastname: Beuers
authors.forename: Thomas M
authors.initials: TM
authors.lastname: van Gulik
mesh_terms: D003937:Diagnosis, Differential; D006391:Hemangioma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D059885:Kasabach-Merritt Syndrome / Q000175:diagnosis / Q000601:surgery; D008113:Liver Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D011379:Prognosis; D057832:Watchful Waiting