title: α-Glucosidase inhibitory hydrolyzable tannins from Eugenia jambolana seeds.
abstract: Three new hydrolyzable tannins including two gallotannins, jamutannins A (1) and B (2), and an ellagitannin, iso-oenothein C (3), along with eight known phenolic compounds were isolated from the seeds of Eugenia jambolana fruit. The structures were elucidated on the basis of spectroscopic data analysis. All compounds isolated were evaluated for α-glucosidase inhibitory effects compared to the clinical drug acarbose.
authors.affiliation: Bioactive Botanical Research Laboratory, Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.
authors.forename: Raed
authors.initials: R
authors.lastname: Omar
authors.forename: Liya
authors.initials: L
authors.lastname: Li
authors.forename: Tao
authors.initials: T
authors.lastname: Yuan
authors.forename: Navindra P
authors.initials: NP
authors.lastname: Seeram
mesh_terms: D065089:Glycoside Hydrolase Inhibitors; D047348:Hydrolyzable Tannins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D007004:Hypoglycemic Agents; D007194:India; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010946:Plants, Medicinal / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry; D027842:Syzygium / Q000737:chemistry*
chemical_list: D065089:Glycoside Hydrolase Inhibitors; D047348:Hydrolyzable Tannins; D007004:Hypoglycemic Agents; C576132:iso-oenothein C; C576131:jamutannin A; C576130:jamutannin B