title: The pharmaceutical biochemistry group: where pharmaceutical chemistry meets biology and drug delivery.
abstract: Successful drug discovery and development of new therapeutics is a long, expensive multidisciplinary process needing innovation and the integration of smart cutting edge science and technology to overcome the challenges in taking a drug from the bench to the bedside. The research activities  of the Pharmaceutical Biochemistry group span the drug discovery and development process, providing an interface that brings together pharmaceutical chemistry, biochemistry, structural biology, computational chemistry and biopharmaceutics. Formulation and drug delivery are brought into play  at an earlier stage when facing the perennial challenge of transforming a potent molecule in vitro into a therapeutic agent in vivo. Concomitantly, drug delivery results can be understood at a molecular level. This broad range of interdisciplinary research activities and competences  enables us to address key challenges in modern drug discovery and development, provides a powerful collaborative platform for other universities and the pharmaceutical industry and an excellent training platform for pharmacists and pharmaceutical scientists who will later be involved in drug  discovery and development.
authors.affiliation: School of Pharmaceutical Sciences University of Geneva 30 Quai Ernest-Ansermet 1211 Geneva 4, Switzerland. Yogi.Kalia@unige.ch
authors.forename: Yogeshvar N
authors.initials: YN
authors.lastname: Kalia
authors.forename: Remo
authors.initials: R
authors.lastname: Perozzo
authors.forename: Leonardo
authors.initials: L
authors.lastname: Scapozza
mesh_terms: D000279:Administration, Cutaneous; D000077548:Anaplastic Lymphoma Kinase; D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000906:Antibodies / Q000008:administration & dosage / Q000627:therapeutic use; D001671:Biochemistry / Q000639:trends*; D002626:Chemistry, Pharmaceutical / Q000639:trends*; D016503:Drug Delivery Systems / Q000639:trends*; D055808:Drug Discovery; D006801:Humans; D058025:Interdisciplinary Studies; D011487:Protein Conformation; D047428:Protein Kinase Inhibitors / Q000378:metabolism / Q000494:pharmacology; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors / Q000235:genetics; D020794:Receptor Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors; D033581:Stem Cell Transplantation; D013937:Thymidine Kinase / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D000906:Antibodies; D047428:Protein Kinase Inhibitors; D013937:Thymidine Kinase; D000077548:Anaplastic Lymphoma Kinase; D011505:Protein-Tyrosine Kinases; D020794:Receptor Protein-Tyrosine Kinases