title: Absolute configuration and enantiodifferentiation of a hemicryptophane incorporating an azaphosphatrane moiety.
abstract: The hemicryptophane racemate (±)-1 was optically resolved by semipreparative HPLC on Chiralpak IC column. The absolute configuration of each isolated enantiomer was established from the analysis of their electronic circular dichroism spectra. Enantiodifferentiation of the chiral cationic cage (±)-1 was evidenced in solution using Δ-TRISPHAT as chiral solvating agent, and the diastereomeric associations were observed in (1)H and (31)P NMR spectra.
authors.affiliation: Laboratoire de Chimie, CNRS, École Normale Supérieure de Lyon, France.
authors.forename: Elina
authors.initials: E
authors.lastname: Payet
authors.forename: Pascal
authors.initials: P
authors.lastname: Dimitrov-Raytchev
authors.forename: Bastien
authors.initials: B
authors.lastname: Chatelet
authors.forename: Laure
authors.initials: L
authors.lastname: Guy
authors.forename: Stephane
authors.initials: S
authors.lastname: Grass
authors.forename: Jerome
authors.initials: J
authors.lastname: Lacour
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Dutasta
authors.forename: Alexandre
authors.initials: A
authors.lastname: Martinez