title: Impact on storage quality of red blood cells and platelets by ultrahigh-frequency radiofrequency identification tags.
abstract: BACKGROUND
  Compared to ISBT128 code labels, radiofrequency identification (RFID) tags have incomparable advantages and gradually applied in blood management system. However, there is no global standard for the uses of RFID frequency. Even though ISBT recommended high-frequency RFID with 13.56MHz, 820- to 960-MHz ultrahigh frequency (UHF) RFID technology in many ways has even more advantages. For this reason, we studied the effect of UHF RFID tags with 820- to 960-MHz exposure on storage quality of red blood cells (RBCs) and platelets (PLTs).
  
  
  METHODS
  Thirty units of collected and prepared suspended RBCs (sRBCs) and PLTs were divided into two bags, one each for the test and control groups. The sRBCs were stored in 4±2°C refrigerator and the PLTs in a 22±2°C rocking box. The test groups were exposed to RF reader continuously during storage. Sampling at different time points and biologic changes were tested.
  
  
  RESULTS
  As the extension of storage and the pH and chlorine levels in the supernatant of sRBCs were reduced, free hemoglobin, potassium, and sodium increased, but were not significant between test and control groups (p>0.05). During the storage period, the pH levels, PLT count, and PLT aggregation rate were decreased in both test and control groups, but were not significant (p>0.05).
  
  
  CONCLUSIONS
  When exposed to 820- to 960-MHz RF, the biologic and biochemical indexes are not found to be exacerbated during 35 days of storage for sRBCs and 5 days for PLTs, respectively.
authors.affiliation: Department of Transfusion Medicine, Affiliated Hospital of AMMS, PLA, China. wangql77@yahoo.com.cn
authors.forename: Quan-Li
authors.initials: QL
authors.lastname: Wang
authors.forename: Xiao-Wei
authors.initials: XW
authors.lastname: Wang
authors.forename: Hai-Long
authors.initials: HL
authors.lastname: Zhuo
authors.forename: Chun-Yan
authors.initials: CY
authors.lastname: Shao
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
authors.forename: Hai-Ping
authors.initials: HP
authors.lastname: Wang
mesh_terms: D001792:Blood Platelets / Q000502:physiology / Q000528:radiation effects*; D001793:Blood Preservation / Q000295:instrumentation / Q000379:methods*; D004909:Erythrocyte Indices; D004912:Erythrocytes / Q000502:physiology / Q000528:radiation effects*; D006801:Humans; D010974:Platelet Aggregation; D010976:Platelet Count; D011356:Product Labeling / Q000295:instrumentation / Q000379:methods*; D011846:Radio Waves