title: Geriatric assessment and chronic kidney disease in the oldest old: the Octabaix study.
abstract: BACKGROUND
  The prevalence of chronic kidney disease (CKD) in older people is increasing. We determine the proportion of CKD in a sample of 321, 85-year-old community-dwelling subjects, and assess the association of socio-demographic data, global geriatric assessment data and comorbidity with CKD according to the estimated glomerular filtration rate (eGFR) of subjects.
  
  
  METHODS
  Serum creatinine, eGFR (derived in ml/min/1.73 m(2) using the Modification of Diet in Renal Disease formula), socio-demographic variables, the Barthel Index (BI), the Spanish version of the Mini-Mental State Examination (MEC), the Mini Nutritional Assessment (MNA), the Charlson Index, the Gait Rating Scale, social risk, quality of life and prevalent chronic diseases were collected.
  
  
  RESULTS
  CKD prevalence was 56.7% for eGFR < 60 ml/min/1.73 m(2), 19.9% for eGFR < 45 ml/min/1.73 m(2) and 6.6% for GFR < 30 ml/min/1.73 m(2). Multiple logistic regression analysis showed that a prior diagnosis of hypertension was associated with an eGFR < 60 ml/min/1.73 m(2) (p<0.008, OR 2.134, 95% CI 1.216-3.744). A diagnosis of heart failure (p<0.001, OR 3.610, 95% CI 1.677-7.771) and a poor score on the quality of life measure (p<0.008, OR 0.9660, 95% CI 0.966-0.995) were associated with an eGFR < 45 ml/min/1.73 m(2).
  
  
  CONCLUSIONS
  More than half of the oldest old in this study had an eGFR < 60 ml/min/1.73 m(2). A history of hypertension was associated with CKD. The group of patients with an eGFR < 45 ml/min/1.73 m(2) was associated with a diagnosis of heart failure and a worse quality of life.
authors.affiliation: Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain. fformiga@bellvitgehospital.cat
authors.forename: Francesc
authors.initials: F
authors.lastname: Formiga
authors.forename: Assumpta
authors.initials: A
authors.lastname: Ferrer
authors.forename: Josep Maria
authors.initials: JM
authors.lastname: Cruzado
authors.forename: Gloria
authors.initials: G
authors.lastname: Padros
authors.forename: Marta
authors.initials: M
authors.lastname: Fanlo
authors.forename: Beatriz
authors.initials: B
authors.lastname: Roson
authors.forename: Ramón
authors.initials: R
authors.lastname: Pujol
mesh_terms: D000203:Activities of Daily Living; D000369:Aged, 80 and over; D015331:Cohort Studies; D015897:Comorbidity; D003404:Creatinine / Q000097:blood; D005260:Female; D005684:Gait; D015577:Geriatric Assessment / Q000706:statistics & numerical data*; D005919:Glomerular Filtration Rate; D006333:Heart Failure / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008297:Male; D015596:Nutrition Assessment; D015995:Prevalence; D011788:Quality of Life; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology*; D013030:Spain / Q000453:epidemiology
chemical_list: D003404:Creatinine