title: Effects of moderate and high intensity exercise on T1/T2 balance.
abstract: Type 1 (TI) and Type 2 (T2) lymphocytes promote cell-mediated immunity and humoral immunity respectively. Evidence accumulated over the past two decades has demonstrated diverse responses of T1 and T2 cells to acute exercise or long-term training at moderate and high intensities. This brief review highlights the current findings from animal and human experimental models on the relationship between the T1 and T2 cell counts and the cytokines these cells produce, in response to moderate and high intensity exercise. The potential of using the T1/T2 balance as an indicator of immune function changes in response to exercise is discussed.
authors.affiliation: Department of Physical Education, Nanchang University, Nanchang, China.
authors.forename: Guanggao
authors.initials: G
authors.lastname: Zhao
authors.forename: Shi
authors.initials: S
authors.lastname: Zhou
authors.forename: Allan
authors.initials: A
authors.lastname: Davie
authors.forename: Quansheng
authors.initials: Q
authors.lastname: Su
mesh_terms: D000367:Age Factors; D000818:Animals; D015415:Biomarkers / Q000097:blood; D015444:Exercise / Q000502:physiology*; D006801:Humans; D007111:Immunity, Cellular / Q000502:physiology; D056724:Immunity, Humoral / Q000502:physiology; D007371:Interferon-gamma / Q000276:immunology / Q000378:metabolism; D015847:Interleukin-4 / Q000276:immunology / Q000378:metabolism; D051379:Mice; D010807:Physical Endurance / Q000502:physiology; D018417:Th1 Cells / Q000276:immunology* / Q000378:metabolism; D018418:Th2 Cells / Q000276:immunology* / Q000378:metabolism; D013997:Time Factors
chemical_list: D015415:Biomarkers; D015847:Interleukin-4; D007371:Interferon-gamma