title: A new cytotoxic dinaphthofuran-7,12-dione derivatives from the seeds of Impatiens balsamina.
abstract: OBJECTIVE
  To study the chemical constituents of seeds of Impatiens balsamina.
  
  
  METHODS
  The chemical constituents of the plant were isolated and purified by column chromatography and their structures were elucidated on the basis of physicochemical properties and spectral date.
  
  
  RESULTS
  A new dinaphthofuran-7,12-dione derivative, named balsaminone C(1), with another two known dinaphthofuran-7,12-dione derivatives, balsaminone A (2), balsaminone B (3) were isolated.
  
  
  CONCLUSIONS
  Compound 1 is a new compound. These compounds exhibit cytotoxicity against cancer cell lines A549, Bel-7402 and Hela. Compound 1 is worth to be further studied as potential anticancer agent.
authors.affiliation: Jiangsu Province Institute of Traditional Chinese Medicine, Nanjing 210028, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Pei
authors.forename: Jing
authors.initials: J
authors.lastname: Lei
authors.forename: Shi-Hui
authors.initials: SH
authors.lastname: Qian
mesh_terms: D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006367:HeLa Cells; D006801:Humans; D029069:Impatiens / Q000737:chemistry*; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D009285:Naphthoquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D012639:Seeds / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D009285:Naphthoquinones; C115539:balsaminone A; C115540:balsaminone B