title: Pulmonary tuberculosis with neuromyelitis optica: an uncommon association of a common disease.
abstract: Systemic tuberculosis has been reported with varying neurological manifestations like meningitis, tuberculomas, myositis and neuropathy. Neuromyelitis optica (NMO) is a well known neurological entity which has been described in association with several systemic disorders like systemic lupus erythematosis, diabetes mellitus, hypothyroidism, exposure to insecticides etc. However, only a few cases of NMO have been reported in association with Mycobacterium tuberculosis. Here, we report a case of pulmonary tuberculosis in association with NMO to highlight the under-reported association of NMO with pulmonary tuberculosis presenting in a peculiar anatomical fashion i.e. longitudinal myelitis with predominant posterior column involvement.
authors.affiliation: Department of Neurology, Liaquat National Hospital, Institute for Postgraduate Medical Studies and Health Sciences, Karachi. ghaniasiddiqi@yahoo.com
authors.forename: Shaista A
authors.initials: SA
authors.lastname: Siddiqi
authors.forename: Mubashira
authors.initials: M
authors.lastname: Hashmi
authors.forename: Zeeshan
authors.initials: Z
authors.lastname: Azmat
authors.forename: Shahid
authors.initials: S
authors.lastname: Mustafa
authors.forename: Khurram A
authors.initials: KA
authors.lastname: Siddiqui
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D009471:Neuromyelitis Optica / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013183:Sputum / Q000382:microbiology; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D000893:Anti-Inflammatory Agents; D000995:Antitubercular Agents; D008775:Methylprednisolone