title: A ruthenium(II) complex with environment-responsive dual emission and its application in the detection of cysteine/homocysteine.
abstract: A ruthenium polypyridine complex [Ru(phen)(2)(IPBA)](PF(6))(2) (complex 1) (IPBA = 4-(1H-imidazo[4,5-f][1,9]phenanthroline-2-yl)benzaldehyde), which displays environment-responsive dual emissive properties, was designed and synthesized. In aprotic solvent, such as DMSO, DMF or CH(3)CN, the complex emits strong cyan light. When in protic solvent, it emits orange light. Similarly, the response of the complex to homocysteine and cysteine (Hcy/Cys) also shows obvious solvent dependence. TDDFT calculations reveal that the protonation of imidazole nitrogen in protic solution is responsible for the luminescent red shift. Hence, the complex could be used to detect Hcy/Cys in aprotic solvent, as well as in protic solvent.
authors.affiliation: Institute of Molecular Science, Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Shanxi University, Taiyuan 030006, PR China. huilichen@sxu.edu.cn
authors.forename: Huili
authors.initials: H
authors.lastname: Chen
authors.forename: Xiaokai
authors.initials: X
authors.lastname: Li
authors.forename: Yanbo
authors.initials: Y
authors.lastname: Wu
authors.forename: Wei
authors.initials: W
authors.lastname: Gao
authors.forename: Ruichun
authors.initials: R
authors.lastname: Bai
mesh_terms: D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry*; D003545:Cysteine / Q000032:analysis*; D006710:Homocysteine / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D010618:Phenanthrolines / Q000737:chemistry; D011789:Quantum Theory; D012428:Ruthenium / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013053:Spectrophotometry
chemical_list: D056831:Coordination Complexes; D010618:Phenanthrolines; D012997:Solvents; D006710:Homocysteine; D012428:Ruthenium; D003545:Cysteine