title: [Effects of "attenuation and synergia" for Bushenhuoxue Granules on Parkinson's patients].
abstract: OBJECTIVE
  To study the effects of "Attenuation and Synergia" for Bushenhuoxue Granules (BSHXG) on Parkinson's patients.
  
  
  METHODS
  120 patients were enrolled and divided into two groups randomly, the control group were treated with placebo and treatment group with BSHXG, both groups based on Madopar treatment. Double-blinded clinical trial was adopted in treatment period. Follow-up period for 6 months. Usage of Madopar and score of treatment complications were adopted to measure related motor complications before and after treatment.
  
  
  RESULTS
  Usage of Madopar and score of treatment complications in treatment group were decreased (P < 0.05). No adverse effects were found in this trial.
  
  
  CONCLUSIONS
  BSHXG can decrease the side-effects of Madopar and put off the development of PD. The effects of "Attenuation and Synergia" of BSHXG becomes clear with time.
authors.affiliation: Department of Traditional Chinese Medicine, General Hospital of Chinese PLA, Beijing 100853, China. kittenlee1115@126.com
authors.forename: Min
authors.initials: M
authors.lastname: Li
authors.forename: Ming-Hui
authors.initials: MH
authors.lastname: Yang
authors.forename: Yi
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D000978:Antiparkinson Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001545:Benserazide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D003248:Constipation / Q000453:epidemiology / Q000209:etiology; D004311:Double-Blind Method; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007980:Levodopa / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy* / Q000503:physiopathology; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D016896:Treatment Outcome; D014555:Urination Disorders / Q000453:epidemiology / Q000209:etiology
chemical_list: D000978:Antiparkinson Agents; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; C005177:benserazide, levodopa drug combination; C527851:bushen huoxue; D007980:Levodopa; D001545:Benserazide