title: A mathematical model for the dynamics of malaria in mosquitoes feeding on a heterogeneous host population.
abstract: We describe and develop a difference equation model for the dynamics of malaria in a mosquito population feeding on, infecting and getting infected from a heterogeneous population of hosts. Using the force of infection from different classes of humans to mosquitoes as parameters, we evaluate a number of entomological parameters, indicating malaria transmission levels, which can be compared to field data. By assigning different types of vector control interventions to different classes of humans and by evaluating the corresponding levels of malaria transmission, we can compare the effectiveness of these interventions. We show a numerical example of the effects of increasing coverage of insecticide-treated bed nets in a human population where the predominant malaria vector is Anopheles gambiae.
authors.affiliation: Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland. nakul.chitnis@unibas.ch
authors.forename: Nakul
authors.initials: N
authors.lastname: Chitnis
authors.forename: Thomas
authors.initials: T
authors.lastname: Smith
authors.forename: Richard
authors.initials: R
authors.lastname: Steketee
mesh_terms: D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D009033:Culicidae / Q000469:parasitology*; D005260:Female; D006801:Humans; D008288:Malaria / Q000469:parasitology* / Q000635:transmission; D008954:Models, Biological; D015233:Models, Statistical; D008962:Models, Theoretical; D009032:Mosquito Control; D010058:Oviposition; D010961:Plasmodium / Q000378:metabolism*; D011157:Population Dynamics; D011336:Probability; D012621:Seasons