title: Implantation of radioactive particles into the cranial base and orbital apex with the use of a magnetic resonance imaging-based surgical navigation system.
abstract: OBJECTIVE
  The aim of this study was try to find a new way with high precision to implant (125)I-radioactive particles for safe and effective control of tumors that have invaded into the cranial base and orbital regions.
  
  
  METHODS
  Eight patients with invasive adenoid cystic carcinoma of the cranial base and orbital apex and a history of multiple surgeries were selected. A preoperative magnetic resonance scan was performed and the Brainlab surgical navigation system was used to aid the surgery.
  
  
  RESULTS
  The radioactive particles were distributed evenly within the tissue and accurately positioned. No intracranial injury or visual impairment occurred, and the treatment was effective.
  
  
  CONCLUSIONS
  The implantation of radioactive particles with the use of magnetic resonance imaging guidance is an effective and safe method for treating invasive malignancies of the skull base and orbital apex, and it should be considered for conditional use.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Chinese PLA General Hospital, Beijing, China.
authors.forename: Yipeng
authors.initials: Y
authors.lastname: Ren
authors.forename: Rongfa
authors.initials: R
authors.lastname: Bu
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Xuelei
authors.initials: X
authors.lastname: Huang
authors.forename: Yunli
authors.initials: Y
authors.lastname: Li
mesh_terms: D000328:Adult; D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods*; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage; D053783:Magnetic Resonance Imaging, Interventional; D008297:Male; D008875:Middle Aged; D009915:Orbit / Q000473:pathology / Q000601:surgery; D009918:Orbital Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D019291:Skull Base / Q000473:pathology / Q000601:surgery; D012888:Skull Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D007457:Iodine Radioisotopes