title: Digital ischemia as a paraneoplastic consequence of squamous cell lung carcinoma.
abstract: We report the case of a 40-year-old man who presented with digital ischemia and squamous cell lung carcinoma. Based on review of the literature, to our knowledge this case represents the youngest patient with lung carcinoma associated with digital ischemia and the only one with this type of tumor. The patient's digital ischemia symptoms improved rapidly with systemic chemotherapy; however, he did eventually lose the distal portion of 1 finger to dry gangrene and mummification.
authors.affiliation: Department of Hematology/Oncology, Marshfield Clinic Weston Center, 3501 Cranberry Blvd, Weston, WI 54476, USA. onitilo.adedayo@marshfieldclinic.org
authors.forename: Adedayo A
authors.initials: AA
authors.lastname: Onitilo
authors.forename: Jennifer
authors.initials: J
authors.lastname: Demos-Bertrand
authors.forename: Jill
authors.initials: J
authors.lastname: Depke
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Resnick
authors.forename: Jessica
authors.initials: J
authors.lastname: Engel
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000188:drug therapy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005385:Fingers / Q000098:blood supply* / Q000473:pathology*; D005734:Gangrene; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000209:etiology*; D008175:Lung Neoplasms / Q000150:complications* / Q000188:drug therapy; D008297:Male