title: Inhibition of pleural metastasis of collecting duct carcinoma of the kidney by modified cytokine-induced killer cells: A case report and review of the literature.
abstract: Collecting duct carcinoma (CDC) or Bellini duct carcinoma of the kidney is a rare, but highly aggressive renal epithelial malignancy, with an extremely poor prognosis. Modified cytokine-induced killer (mCIK) cells were injected into the pleural cavity to treat pleural metastasis of CDC. The patient, a 33-year-old male, was admitted to hospital for further treatment for severe pleural metastasis of CDC. We cured the pleural metastasis through intrapleural infusion with mCIK cells. After receiving this innovative treatment, the patient exhibited a positive response: the cough, dyspnea, chest distress and thoracalgia were evidently relieved, while the pleural fluid became clear after exhibiting haematodes and its level decreased significantly. The patient achieved partial success. This novel immunotherapy method is a promising treatment for patients with refractory pleural metastasis.
authors.affiliation: Cancer Biotherapy Center, the Third Affiliated Hospital, Kunming Medical College, Kunming.
authors.forename: Jingyi
authors.initials: J
authors.lastname: Liu
authors.forename: Jun
authors.initials: J
authors.lastname: Sui
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Zhang
authors.forename: Xiubao
authors.initials: X
authors.lastname: Ren
authors.forename: Li
authors.initials: L
authors.lastname: Luan
authors.forename: Qisheng
authors.initials: Q
authors.lastname: Yang
authors.forename: Songhai
authors.initials: S
authors.lastname: Gu
authors.forename: Rudolf
authors.initials: R
authors.lastname: Wank
authors.forename: Barbara
authors.initials: B
authors.lastname: Laumbacher
authors.forename: Xin
authors.initials: X
authors.lastname: Song