title: Degenerative lumbar spinal stenosis: evaluation and management.
abstract: Degenerative lumbar spinal stenosis is caused by mechanical factors and/or biochemical alterations within the intervertebral disk that lead to disk space collapse, facet joint hypertrophy, soft-tissue infolding, and osteophyte formation, which narrows the space available for the thecal sac and exiting nerve roots. The clinical consequence of this compression is neurogenic claudication and varying degrees of leg and back pain. Degenerative lumbar spinal stenosis is a major cause of pain and impaired quality of life in the elderly. The natural history of this condition varies; however, it has not been shown to worsen progressively. Nonsurgical management consists of nonsteroidal anti-inflammatory drugs, physical therapy, and epidural steroid injections. If nonsurgical management is unsuccessful and neurologic decline persists or progresses, surgical treatment, most commonly laminectomy, is indicated. Recent prospective randomized studies have demonstrated that surgery is superior to nonsurgical management in terms of controlling pain and improving function in patients with lumbar spinal stenosis.
authors.affiliation: Hospital for Special Surgery, New York, NY, USA.
authors.forename: Paul S
authors.initials: PS
authors.lastname: Issack
authors.forename: Matthew E
authors.initials: ME
authors.lastname: Cunningham
authors.forename: Matthias
authors.initials: M
authors.lastname: Pumberger
authors.forename: Alexander P
authors.initials: AP
authors.lastname: Hughes
authors.forename: Frank P
authors.initials: FP
authors.lastname: Cammisa
mesh_terms: D019299:Decompression, Surgical / Q000379:methods; D006801:Humans; D007796:Laminectomy / Q000009:adverse effects / Q000379:methods; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D011859:Radiography; D013130:Spinal Stenosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D016896:Treatment Outcome