title: Expression pattern of Galectin 4 in rat placentation.
abstract: Galectin 4 (Gal4) is abundantly expressed in the epithelium of the gastrointestinal tract, and functional analysis has concentrated on its roles associated with polarized membrane trafficking. This study aimed to investigate the expression of Gal4 in placentation. The expression level of Gal4 was revealed to be lower in differentiated Rcho-1 cells (a model system of rat trophoblast differentiation) than in proliferative cells. In the rat placenta, immunohistochemical analysis showed that Gal4 is preferentially located in the maternal-fetal junctional zone. These results suggest that down-regulation of Gal4 may be involved in the promotion of trophoblast cell differentiation.
authors.affiliation: Department of Biology, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa 920-0293, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Arikawa
authors.forename: E
authors.initials: E
authors.lastname: Simamura
authors.forename: H
authors.initials: H
authors.lastname: Shimada
authors.forename: N
authors.initials: N
authors.lastname: Nishi
authors.forename: T
authors.initials: T
authors.lastname: Tatsuno
authors.forename: Y
authors.initials: Y
authors.lastname: Ishigaki
authors.forename: N
authors.initials: N
authors.lastname: Tomosugi
authors.forename: C
authors.initials: C
authors.lastname: Yamashiro
authors.forename: T
authors.initials: T
authors.lastname: Hata
authors.forename: T
authors.initials: T
authors.lastname: Takegami
authors.forename: H
authors.initials: H
authors.lastname: Mogami
authors.forename: K
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: T
authors.initials: T
authors.lastname: Nakamura
authors.forename: H
authors.initials: H
authors.lastname: Otani
authors.forename: T
authors.initials: T
authors.lastname: Hatta
authors.forename: H
authors.initials: H
authors.lastname: Shoji
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D015536:Down-Regulation; D005260:Female; D037541:Galectin 4 / Q000096:biosynthesis*; D010920:Placenta / Q000378:metabolism; D010929:Placentation / Q000502:physiology*; D011247:Pregnancy; D051381:Rats
chemical_list: D037541:Galectin 4