title: [Efficacy and safety of insulin aspart versus regular human insulin for women with gestational diabetes mellitus].
abstract: OBJECTIVE
  To explore the efficacy and safety of human aspart versus regular human insulin in women with gestational diabetes mellitus (GDM).
  
  
  METHODS
  A total of 80 women with GDM during pregnancy delivered at our hospital divided into 2 groups: Group 1 with human aspart and regular human insulin N while Group 2 with regular human insulin R and N. The levels of glucose were compared before and after 2 h at breakfast, lunch and supper at Day 1, 3 and 5. And the outcomes of women and their babies were evaluated.
  
  
  RESULTS
  No significant difference in general characteristics existed between two groups. Except for breakfast of Day 3, no significant difference was found in terms of the amount of insulin, the time of satisfactory glucose level and delivery time point, etc. There was no significant inter-group difference in the outcomes of pregnant women and their babies.
  
  
  CONCLUSIONS
  The efficacy and safety of human aspart or regular human insulin are comparable for the women with gestational diabetes mellitus.
authors.affiliation: Department of Obstetrics, Beijing Obstetrics & Gynecology Hospital, Capital Medical University, Beijing 100026, China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhou
authors.forename: Ling
authors.initials: L
authors.lastname: Fan
mesh_terms: D016640:Diabetes, Gestational / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007328:Insulin / Q000627:therapeutic use*; D061267:Insulin Aspart / Q000627:therapeutic use*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011256:Pregnancy Outcome; D016896:Treatment Outcome
chemical_list: D007328:Insulin; D061267:Insulin Aspart