title: Dietary calcium intake, vitamin D levels, and breast cancer risk: a dose-response analysis of observational studies.
abstract: Results from the recent meta-analysis suggested a favorable effect of dietary calcium and vitamin D levels on breast cancer risk. However, the relationship of dietary calcium and vitamin D levels with breast cancer risk is unclear. Thus, the dose-response relationship was assessed by restricted cubic spline model and multivariate random-effect meta-regression. Results suggested that women might suffer from the lowest risk of breast cancer with dietary calcium intake of about 600 mg/day, dietary vitamin D intake of about 400 IU/day, and serum vitamin D levels of about 30 ng/ml.
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Hong
authors.forename: Changwei
authors.initials: C
authors.lastname: Tian
authors.forename: Xingliang
authors.initials: X
authors.lastname: Zhang
mesh_terms: D001943:Breast Neoplasms / Q000097:blood / Q000178:diet therapy / Q000378:metabolism / Q000473:pathology; D002136:Calcium, Dietary / Q000008:administration & dosage / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D012307:Risk Factors; D014807:Vitamin D / Q000008:administration & dosage / Q000097:blood / Q000378:metabolism
chemical_list: D002136:Calcium, Dietary; D014807:Vitamin D