title: Management of recurrent acute otitis media in children: systematic review of the effect of different interventions on otitis media recurrence, recurrence frequency and total recurrence time.
abstract: OBJECTIVE
  To conduct a systematic review comparing the effect of three interventions (prophylactic antibiotics, tympanostomy tube insertion and adenoidectomy) on otitis media recurrence, recurrence frequency and total recurrence time.
  
  
  METHODS
  Literature on recurrent otitis media was identified using the PubMed and Scopus search engines for the period January 1990 to March 2011. A hand search of the reference lists of relevant articles and textbooks was conducted to identify additional studies. Randomised, controlled trials with a minimum of 40 children and follow up of at least 12 months were included.
  
  
  RESULTS
  Eighteen publications were identified. Each was assessed using preset inclusion criteria; seven publications met these criteria.
  
  
  CONCLUSIONS
  Prophylactic antibiotics are effective in reducing otitis media recurrence, recurrence frequency and total recurrence time. Tympanostomy tube insertion failed to reduce the prevalence of otitis media recurrence, but reduced the recurrence frequency and total recurrence time. Adenoidectomy reduced otitis media recurrence; results on otitis media recurrence frequency differed but on average there was a reduction; however, the two studies with relevant data on total recurrence time had contradictory results.
authors.affiliation: Department of Otolaryngology, Ninewells Hospital and University of Dundee Medical School, Dundee, Scotland, UK.
authors.forename: K H
authors.initials: KH
authors.lastname: Cheong
authors.forename: S S M
authors.initials: SS
authors.lastname: Hussain
mesh_terms: D000208:Acute Disease; D000233:Adenoidectomy; D000658:Amoxicillin / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008876:Middle Ear Ventilation; D010033:Otitis Media / Q000453:epidemiology / Q000628:therapy*; D015995:Prevalence; D016032:Randomized Controlled Trials as Topic; D055502:Secondary Prevention; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000658:Amoxicillin