title: 120W GreenLight High Performance System laser for benign prostate hyperplasia: 68 patients with 3-year follow-up and analysis of predictors of response.
abstract: OBJECTIVE
  To investigate 3-year postoperative results of photoselective vaporization of the prostate using the 120W GreenLight High Performance System photoselective vaporization of the prostate (HPS-PVP) for treating benign prostate hyperplasia (BPH) >30 mL.
  
  
  METHODS
  Records of 68 of 85 men who underwent HPS-PVP and were followed up for 3 years were analyzed retrospectively. Patients were older than 50 years with prostate volume >30 mL, International Prostate Symptom Score (IPSS) ≥8, maximum flow rate (Q(max.)) <15 mL/s, and bladder outlet obstruction (BOO) index ≥20. Parameters, including IPSS and Q(max.), were measured at baseline and 6, 12, 24, and 36 months postoperatively. Patients who improved by at least 30% from baseline IPSS scores were considered responders, and logistic regression analysis was done to determine predictors of response.
  
  
  RESULTS
  Mean age, prostate volume, IPSS, Q(max.), and operative time were 71.6 ± 7.3 years, 50.0 ± 17.0 mL, 21.7 ± 7.9, 8.7 ± 3.1 mL/s, and 60.6 ± 31.9 minutes, respectively. Six months postoperatively, 50 (73.5%) patients responded with respect to IPSS score, and 40 (58.8%) maintained improvements at 3 years postoperatively. Analysis at 3-year follow-up showed that for IPSS ≥19, the higher the IPSS the greater the functional bladder capacity (FBC) and the lower the frequency of nocturia; and for BOO index ≥40, the higher the BOO index the better the response.
  
  
  CONCLUSIONS
  HPS-PVP is a safe and effective procedure for treating BPH, having demonstrated that 60% of patients maintained efficacy at 3 years postoperatively. Baseline IPSS, FBC, nocturia, BOO index, and bladder contractility index were valuable for predicting response to surgery.
authors.affiliation: Department of Urology, Seoul National University, Boramae Medical Center, Seoul, Republic of Korea.
authors.forename: Sung Yong
authors.initials: SY
authors.lastname: Cho
authors.forename: Sohyun
authors.initials: S
authors.lastname: Park
authors.forename: Min Young
authors.initials: MY
authors.lastname: Jeong
authors.forename: Yun Kwan
authors.initials: YK
authors.lastname: Ro
authors.forename: Hwancheol
authors.initials: H
authors.lastname: Son
mesh_terms: D000368:Aged; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects / Q000379:methods*; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D011379:Prognosis; D011470:Prostatic Hyperplasia / Q000601:surgery*; D012189:Retrospective Studies; D013997:Time Factors