title: Oxidative degradation of chemical warfare agents in water by bleaching powder.
abstract: Degradation of sulfur mustard (HD), S-2-(di-isopropylamino)ethyl O-ethyl methylphosphonothioate (VX) and Soman (GD) in water by bleaching powder was investigated. The degradation products were comprehensively analyzed by gas chromatography/mass spectrometry (GC/MS), liquid chromatography/mass spectrometry (LC/MS) and ion chromatography. Degradation pathways were deduced based on the identified products. The product analysis results indicated that HD could be degraded through oxidation and chlorination reactions, and a small portion of sulfur atoms could be mineralized into SO(4)(2-) ion. Oxidative degradation of VX could finally generate O-ethyl methylphosphonate acid (EMPA), sulfonic acids, SO(4)(2-) and NO(3)(-) ions. GD would be converted into non-toxic pinacolyl methylphosphonate via nucleophilic substitution.
authors.affiliation: Institute of Chemical Defence, P.O. Box 1048, 102205 Beijing, China.
authors.forename: Lihong
authors.initials: L
authors.lastname: Qi
authors.forename: Guomin
authors.initials: G
authors.lastname: Zuo
authors.forename: Zhenxing
authors.initials: Z
authors.lastname: Cheng
authors.forename: Haiyan
authors.initials: H
authors.lastname: Zhu
authors.forename: Shanmao
authors.initials: S
authors.lastname: Li
mesh_terms: D000631:Aminopyridines / Q000737:chemistry; D002619:Chemical Warfare Agents / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D009151:Mustard Gas / Q000737:chemistry; D009946:Organothiophosphorus Compounds / Q000737:chemistry; D010084:Oxidation-Reduction; D012999:Soman / Q000737:chemistry; D013449:Sulfonamides / Q000737:chemistry; D013451:Sulfonic Acids / Q000737:chemistry
chemical_list: D000631:Aminopyridines; D002619:Chemical Warfare Agents; C546023:N-ethyl-2-((6-methoxy-pyridin-3-yl)-(toluene-2-sulphonyl)amino)-N-pyridin-3-ylmethyl-acetamide; D009946:Organothiophosphorus Compounds; D013449:Sulfonamides; D013451:Sulfonic Acids; D012999:Soman; D009151:Mustard Gas