title: GOx signaling triggered by aptamer-based ATP detection.
abstract: Aptamer based ATP binding leads to the release of the co-factor FAD, which acts as a trigger to 'turn-on' the activity of apo-GOx and thus generates a measurable response.
authors.affiliation: Department of Chemistry, Xavier University of Louisiana, 1 Drexel Drive, New Orleans, LA 70125, USA.
authors.forename: Sarita
authors.initials: S
authors.lastname: Sitaula
authors.forename: Shirmir D
authors.initials: SD
authors.lastname: Branch
authors.forename: Mehnaaz F
authors.initials: MF
authors.lastname: Ali
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism*; D052157:Aptamers, Nucleotide / Q000378:metabolism*; D015374:Biosensing Techniques / Q000379:methods*; D004800:Enzymes, Immobilized / Q000737:chemistry / Q000378:metabolism; D005182:Flavin-Adenine Dinucleotide / Q000378:metabolism; D005949:Glucose Oxidase / Q000737:chemistry / Q000378:metabolism*
chemical_list: D052157:Aptamers, Nucleotide; D004800:Enzymes, Immobilized; D005182:Flavin-Adenine Dinucleotide; D000255:Adenosine Triphosphate; D005949:Glucose Oxidase