title: The high prevalence of Torque teno virus DNA in blood donors and haemodialysis patients in southern Brazil.
abstract: This study investigates the frequency of Torque teno virus (TTV) infection in 150 blood donors and 77 patients requiring haemodialysis in southern Brazil. Plasma samples were screened for TTV DNA using polymerase chain reaction (PCR). The prevalences of TTV among blood donors and patients requiring haemodialysis were 73.3% and 68.8%, respectively. The presence of TTV was correlated with age in the blood donors (p = 0.024). In haemodialysis patients, no association was found between TTV infection and the demographic parameters (age, sex and education), the duration of haemodialysis or a history of blood transfusion. This study is the first to evaluate the prevalence of TTV infection in Brazilian patients requiring haemodialysis.
authors.affiliation: Programa de Pós-graduação em Diagnóstico Genético e Molecula, Universidade Luterana do Brasil, Canoas, RS, Brasil, 92425-900.
authors.forename: Aline
authors.initials: A
authors.lastname: Massaú
authors.forename: Cristiana
authors.initials: C
authors.lastname: Martins
authors.forename: Gilca Costa
authors.initials: GC
authors.lastname: Nachtigal
authors.forename: Anelise Bergmann
authors.initials: AB
authors.lastname: Araújo
authors.forename: Maria Lucia
authors.initials: ML
authors.lastname: Rossetti
authors.forename: Christian
authors.initials: C
authors.lastname: Niel
authors.forename: Cláudia Maria Dornelles
authors.initials: CM
authors.lastname: da Silva
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001782:Blood Donors; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D004266:DNA Virus Infections / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D004522:Educational Status; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D015995:Prevalence; D006435:Renal Dialysis; D012307:Risk Factors; D013997:Time Factors; D022783:Torque teno virus / Q000235:genetics / Q000302:isolation & purification*; D055815:Young Adult