title: Percutaneous balloon-expandable covered stent implantation for treatment of traumatic aortic injury in children and adolescents.
abstract: Surgical treatment of pediatric acute traumatic aortic injury (TAI) after blunt chest trauma is standard of care. Use of endovascular stent grafts for treatment of TAI in adults is common but has important limitations in children. We sought to describe the use of balloon-expandable covered endovascular stents for treatment of TAI in children and adolescents. Participants of the multicenter Coarctation of the Aorta Stent Trial (COAST) had access to investigational large-diameter, balloon-expandable, covered stents (covered Cheatham-platinum stents; NuMed, Inc., Hopkinton, New York) on an emergency-use basis. From 2008 through 2011, 6 covered stents were implanted in 4 patients at 3 COAST centers for treatment of TAI. Median patient age was 13.5 years (range 11 to 14) and weight was 58 kg (40 to 130). All patients sustained severe extracardiac injuries that were judged to preclude safe open surgical repair of TAI. Median aortic isthmus and stent implantation balloon diameters were 16.4 mm (13.2 to 19) and 19 mm (16 to 20), respectively. Stent implantation was technically successful in all attempts. Complete exclusion of aortic wall injury was achieved in all cases. There were no access site complications. At a median follow-up of 24 months, there was 1 early death (related to underlying head trauma) and 1 patient with recurrent aortic aneurysm who required additional stent implantation. In conclusion, balloon-expandable covered-stent implantation for treatment of pediatric TAI after blunt trauma is generally safe and effective. Availability of this equipment may alter the standard approach to treatment of pediatric TAI.
authors.affiliation: The Heart Institute, Division of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA. bryan.goldstein@cchmc.org
authors.forename: Bryan H
authors.initials: BH
authors.lastname: Goldstein
authors.forename: Russel
authors.initials: R
authors.lastname: Hirsch
authors.forename: Matthew E
authors.initials: ME
authors.lastname: Zussman
authors.forename: Julie A
authors.initials: JA
authors.lastname: Vincent
authors.forename: Alejandro J
authors.initials: AJ
authors.lastname: Torres
authors.forename: John
authors.initials: J
authors.lastname: Coulson
authors.forename: Richard E
authors.initials: RE
authors.lastname: Ringel
authors.forename: Robert H
authors.initials: RH
authors.lastname: Beekman
mesh_terms: D000293:Adolescent; D001013:Aorta, Thoracic / Q000293:injuries* / Q000601:surgery; D001027:Aortography; D001807:Blood Vessel Prosthesis; D002404:Catheterization / Q000295:instrumentation*; D002648:Child; D020099:Coated Materials, Biocompatible; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011474:Prosthesis Design; D012189:Retrospective Studies; D015607:Stents; D013898:Thoracic Injuries / Q000175:diagnosis / Q000601:surgery*; D016896:Treatment Outcome; D057772:Vascular System Injuries / Q000175:diagnosis / Q000601:surgery*; D014949:Wounds, Nonpenetrating / Q000175:diagnosis / Q000601:surgery
chemical_list: D020099:Coated Materials, Biocompatible