title: Application of ionic liquid for extraction and separation of bioactive compounds from plants.
abstract: In recent years, ionic liquids (ILs), as green and designer solvents, have accelerated research in analytical chemistry. This review highlights some of the unique properties of ILs and provides an overview of the preparation and application of IL or IL-based materials to extract bioactive compounds in plants. IL or IL-based materials in conjunction with liquid-liquid extraction (LLE), ultrasonic-assisted extraction (UAE), microwave-assisted extraction (MAE), high performance liquid chromatography (HPLC) and solid-phase extraction (SPE) analytical technologies etc., have been applied successfully to the extraction or separation of bioactive compounds from plants. This paper reviews the available data and references to examine the advantages of IL and IL-based materials in these applications. In addition, the main target compounds reviewed in this paper are bioactive compounds with multiple therapeutic effects and pharmacological activities. Based on the importance of the targets, this paper reviews the applications of ILs, IL-based materials or co-working with analytical technologies. The exploitation of new applications of ILs on the extraction of bioactive compounds from plant samples is expected to increase.
authors.affiliation: Department of Chemical Engineering, Inha University, Incheon 402-751, Republic of Korea.
authors.forename: Baokun
authors.initials: B
authors.lastname: Tang
authors.forename: Wentao
authors.initials: W
authors.lastname: Bi
authors.forename: Minglei
authors.initials: M
authors.lastname: Tian
authors.forename: Kyung Ho
authors.initials: KH
authors.lastname: Row
mesh_terms: D005591:Chemical Fractionation / Q000379:methods*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D052578:Ionic Liquids / Q000737:chemistry*; D010936:Plant Extracts / Q000302:isolation & purification*; D010944:Plants / Q000737:chemistry*
chemical_list: D052578:Ionic Liquids; D010936:Plant Extracts