title: Iodine(III)-mediated tandem oxidative cyclization for construction of 2-nitrobenzo[b]furans.
abstract: Various 3-alkyl-2-nitrobenzo[b]furans were synthesized from common intermediate 2-(2-nitroethyl)phenols via a hypervalent iodine-induced oxidative cyclization, with good to excellent yields. This facile route is able to efficiently functionalize 2-nitrobenzo[b]furans, which are difficult to obtain by classical methods.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, 2 Nanwei Road, Xicheng Dist., Beijing 100050, People's Republic of China.
authors.forename: Shi-Chao
authors.initials: SC
authors.lastname: Lu
authors.forename: Pu-Rong
authors.initials: PR
authors.lastname: Zheng
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
mesh_terms: D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D003500:Cyclization; D007455:Iodine / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D001572:Benzofurans; C036334:2-nitrobenzofuran; D007455:Iodine