title: Does ionizing radiation influence Alzheimer's disease risk?
abstract: Alzheimer's disease (AD) is a human neurodegenerative disease, and its global prevalence is predicted to increase dramatically in the following decades. There is mounting evidence describing the effects of ionizing radiation (IR) on the brain, suggesting that exposure to IR might ultimately favor the development of AD. Therefore better understanding the possible connections between exposure to IR and AD pathogenesis is of utmost importance. In this review, recent developments in the research on the biological and cognitive effects of IR in the brain will be explored. Because AD is largely an age-related pathology, the effects of IR on ageing will be investigated.
authors.affiliation: Center for Nuclear Medicine and Ultrasound, Rajshahi Medical College Hospital Campus, GPO Box No. 35, Rajshahi, Bangladesh.
authors.forename: Nasrin
authors.initials: N
authors.lastname: Begum
authors.forename: Bing
authors.initials: B
authors.lastname: Wang
authors.forename: Masahiko
authors.initials: M
authors.lastname: Mori
authors.forename: Guillaume
authors.initials: G
authors.lastname: Vares
mesh_terms: D000375:Aging / Q000528:radiation effects*; D000544:Alzheimer Disease / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology*; D001921:Brain / Q000503:physiopathology* / Q000528:radiation effects*; D004781:Environmental Exposure / Q000009:adverse effects / Q000706:statistics & numerical data; D006801:Humans; D015995:Prevalence; D011832:Radiation Injuries / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology*; D011839:Radiation, Ionizing; D018570:Risk Assessment