title: Macular thickness and volume parameters measured using optical coherence tomography (OCT) for evaluation of glaucoma patients.
abstract: The aim of this study was to evaluate macular thickness parameters in glaucoma patients and to compare them to normal subjects using Optical Coherence Tomography (OCT). This prospective, observational study included 20 primary open angle glaucoma patients (POAG) and 20 healthy subjects in control group. Exclusion criteria were diabetes and other macular pathology, like age-related macular degeneration, macular oedema, central serous retinopathy and high myopia >4.00 dsph. OCT imaging of peripapillar retina and macular area were performed using Cirrus HD OCT In these two groups of patients we analyzed changes of macular thickness parameters (central subfield thickness, macular volume, and average macular thickness). The group of glaucoma patients had decreased values of the two macular thickness parameters: macular volume and average macular thickness, compared to control group. There was no difference in central macular thickness, presumably because of the absence of the ganglion cells in this layer. Macular imaging can be a useful additional method to determine glaucoma status and has a potential for tracking glaucoma progression.
authors.affiliation: University of Zagreb, "Sestre milosrdnice" University Hospital Center, Department of Ophthalmology, Zagreb, Croatia. frejabarisic@yahoo.com
authors.forename: Freja
authors.initials: F
authors.lastname: Barisić
authors.forename: Ana Jurin
authors.initials: AJ
authors.lastname: Sicaja
authors.forename: Maja Malenica
authors.initials: MM
authors.lastname: Ravlić
authors.forename: Katia
authors.initials: K
authors.lastname: Novak-Laus
authors.forename: Renata
authors.initials: R
authors.lastname: Iveković
authors.forename: Zdravko
authors.initials: Z
authors.lastname: Mandić
mesh_terms: D000368:Aged; D018450:Disease Progression; D005260:Female; D005902:Glaucoma, Open-Angle / Q000473:pathology*; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D041623:Tomography, Optical Coherence