title: Chemoselective reduction-based fluorescence probe for detection of hydrogen sulfide in living cells.
abstract: A selective and sensitive fluorescence probe for hydrogen sulfide (H(2)S) detection was synthesized and evaluated in PBS buffer and fetal bovine serum. The effect of pH on the probe was also studied. In addition, visualization of H(2)S in Hela cells was achieved using confocal laser scanning fluorescence microscopy.
authors.affiliation: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
authors.forename: Bifeng
authors.initials: B
authors.lastname: Chen
authors.forename: Cong
authors.initials: C
authors.lastname: Lv
authors.forename: Xinjing
authors.initials: X
authors.lastname: Tang
mesh_terms: D002477:Cells / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D006862:Hydrogen Sulfide / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D010084:Oxidation-Reduction; D013194:Staining and Labeling / Q000295:instrumentation
chemical_list: D005456:Fluorescent Dyes; D006862:Hydrogen Sulfide