title: An unusual cause for rings in the brain.
abstract: We report the case of a 35-year-old man from North India who presented with generalised tonic-clonic seizures and was found to have ring-enhancing brain lesions. He had a coincident adrenal mass lesion. Cultures from both regions grew Histoplasma capsulatum. He improved on treatment with itraconazole. This case is being reported since cerebral ring-enhancing lesions are rarely associated with histoplasmosis, and coincident adrenal involvement is also a rarity in an immunocompetent individual.
authors.affiliation: Department of Endocrinology, Diabetes and Metabolism, Christian Medical College, Vellore, India.
authors.forename: Anulekha M
authors.initials: AM
authors.lastname: John
authors.forename: Natarajan
authors.initials: N
authors.lastname: Vasanthi
authors.forename: Abhishek
authors.initials: A
authors.lastname: Khurana
authors.forename: Geeta
authors.initials: G
authors.lastname: Chacko
authors.forename: Promila
authors.initials: P
authors.lastname: Mohanraj
authors.forename: Vedantam
authors.initials: V
authors.lastname: Rajshekhar
authors.forename: Nihal
authors.initials: N
authors.lastname: Thomas
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000209:etiology*; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D012640:Seizures / Q000209:etiology
chemical_list: D017964:Itraconazole