title: Clinical features of Chinese coronary heart disease patients with chronic kidney disease.
abstract: OBJECTIVE
  To investigate the prevalence of chronic kidney disease (CKD) by stage in Chinese patients with coronary heart disease (CHD) and to identify the clinical features and examine control of cardiovascular risk factors.
  
  
  RESULTS
  Clinical data of hospitalized patients were collected by investigators in China. CKD stages were classified according to estimated glomerular filtration rate (eGFR). A total of 2509 participants with CHD were included in the final statistical analysis. The overall prevalence of CKD stage 3 and greater (eGFR of less than 60 mL/min/1.73 m(2)) in the CHD patients was 32.5%. As the CKD stage increased, fasting blood glucose (FBG), systolic blood pressure (SBP), diastolic blood pressure (DBP), and high-sensitivity C-reactive protein (HS-CRP) levels all worsened. As the CKD stage became more severe, CHD patients had comorbidities such as diabetes mellitus, periphery arterial disease, and ischemic stroke, and more CHD patients had triple vessel disease increased. Even when patients received treatment of CHD and risk factors, control of cardiovascular risk factors such as SBP, DBP, FBG, and low-density lipoprotein was worsened as CKD stage became more severe over a 6-week follow-up.
  
  
  CONCLUSIONS
  The data suggested a high prevalence of CKD in Chinese patients with CHD. Many conventional risk factors and comorbidities were correlated with high prevalence of CKD in CHD patients. Control of cardiovascular risk factors in those patients was poor.
authors.affiliation: Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Wang
authors.forename: Dongdong
authors.initials: D
authors.lastname: Zhao
authors.forename: Yan
authors.initials: Y
authors.lastname: Xing
authors.forename: Jue
authors.initials: J
authors.lastname: Li
authors.forename: Dayi
authors.initials: D
authors.lastname: Hu
authors.forename: Yawei
authors.initials: Y
authors.lastname: Xu
authors.forename: Philip A
authors.initials: PA
authors.lastname: Merriam
authors.forename: Yunsheng
authors.initials: Y
authors.lastname: Ma
mesh_terms: D000368:Aged; D044466:Asian People; D002681:China; D015897:Comorbidity; D003327:Coronary Disease / Q000150:complications*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D051436:Renal Insufficiency, Chronic / Q000150:complications* / Q000453:epidemiology / Q000503:physiopathology; D012307:Risk Factors