title: Peripheral prism glasses:  effects of dominance, suppression, and background.
abstract: OBJECTIVE
  Unilateral peripheral prisms for homonymous hemianopia (HH) place different images on corresponding peripheral retinal points, a rivalrous situation in which local suppression of the prism image could occur and thus limit device functionality. Detection with peripheral prisms has primarily been evaluated using conventional perimetry, where binocular rivalry is unlikely to occur. We quantified detection over more visually complex backgrounds and examined the effects of ocular dominance.
  
  
  METHODS
  Detection rates of eight participants with HH or quadranopia and normal binocularity wearing unilateral peripheral prism glasses were determined for static perimetry targets briefly presented in the prism expansion area (in the blind hemifield) and the seeing hemifield, under monocular and binocular viewing, over uniform gray and more complex patterned backgrounds.
  
  
  RESULTS
  Participants with normal binocularity had mixed sensory ocular dominance, demonstrated no difference in detection rates when prisms were fitted on the side of the HH or the opposite side (p > 0.2), and had detection rates in the expansion area that were not different for monocular and binocular viewing over both backgrounds (p > 0.4). However, two participants with abnormal binocularity and strong ocular dominance demonstrated reduced detection in the expansion area when prisms were fitted in front of the non-dominant eye.
  
  
  CONCLUSIONS
  We found little evidence of local suppression of the peripheral prism image for HH patients with normal binocularity. However, in cases of strong ocular dominance, consideration should be given to fitting prisms before the dominant eye. Although these results are promising, further testing in more realistic conditions including image motion is needed.
authors.affiliation: Schepens Eye Research Institute, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts 02114-2500, USA.
authors.forename: Nicole C
authors.initials: NC
authors.lastname: Ross
authors.forename: Alex R
authors.initials: AR
authors.lastname: Bowers
authors.forename: Eli
authors.initials: E
authors.lastname: Peli
mesh_terms: D000221:Adaptation, Ocular / Q000502:physiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D023882:Dominance, Ocular / Q000502:physiology*; D004867:Equipment Design; D005139:Eyeglasses; D005260:Female; D005500:Follow-Up Studies; D006423:Hemianopsia / Q000503:physiopathology / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015348:Vision, Binocular / Q000502:physiology*; D058609:Visual Field Tests; D014794:Visual Fields / Q000502:physiology*; D055815:Young Adult