title: The effects of four hypocaloric diets containing different levels of sucrose or high fructose corn syrup on weight loss and related parameters.
abstract: BACKGROUND
  The replacement of sucrose with HFCS in food products has been suggested as playing a role in the development of obesity as a public health issue. The objective of this study was to examine the effects of four equally hypocaloric diets containing different levels of sucrose or high fructose corn syrup (HFCS).
  
  
  METHODS
  This was a randomized, prospective, double blind trial, with overweight/obese participants measured for body composition and blood chemistry before and after the completion of 12 weeks following a hypocaloric diet. The average caloric deficit achieved on the hypocaloric diets was 309 kcal.
  
  
  RESULTS
  Reductions were observed in all measures of adiposity including body mass, BMI,% body fat, waist circumference and fat mass for all four hypocaloric groups, as well as reductions in the exercise only group for body mass, BMI and waist circumference.
  
  
  CONCLUSIONS
  Similar decreases in weight and indices of adiposity are observed when overweight or obese individuals are fed hypocaloric diets containing levels of sucrose or high fructose corn syrup typically consumed by adults in the United States.
authors.affiliation: Rippe Lifestyle Institute, 215 Celebration Place, Celebration, FL 34747, USA.
authors.forename: Joshua
authors.initials: J
authors.lastname: Lowndes
authors.forename: Diana
authors.initials: D
authors.lastname: Kawiecki
authors.forename: Sabrina
authors.initials: S
authors.lastname: Pardo
authors.forename: Von
authors.initials: V
authors.lastname: Nguyen
authors.forename: Kathleen J
authors.initials: KJ
authors.lastname: Melanson
authors.forename: Zhiping
authors.initials: Z
authors.lastname: Yu
authors.forename: James M
authors.initials: JM
authors.lastname: Rippe
mesh_terms: D050154:Adiposity; D000328:Adult; D015992:Body Mass Index; D015331:Cohort Studies; D004038:Diet, Reducing; D019422:Dietary Sucrose / Q000008:administration & dosage / Q000009:adverse effects*; D004311:Double-Blind Method; D005260:Female; D005431:Florida; D005632:Fructose / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000178:diet therapy*; D050177:Overweight / Q000178:diet therapy*; D012639:Seeds / Q000737:chemistry; D013549:Sweetening Agents / Q000008:administration & dosage / Q000009:adverse effects*; D055105:Waist Circumference; D015431:Weight Loss; D003313:Zea mays / Q000737:chemistry
chemical_list: D019422:Dietary Sucrose; D013549:Sweetening Agents; D005632:Fructose