title: [Clinical analysis of drug-induced Pseudo-Bartter's syndrome: a report of five cases].
abstract: OBJECTIVE
  To summarize the clinical characteristics and outcomes of Pseudo-Bartter's syndrome and explore its pathogenesis.
  
  
  METHODS
  The clinical data of 5 cases of Pseudo-Bartter's syndrome at our ward from May 2008 to December 2010 was analyzed retrospectively.
  
  
  RESULTS
  All patients were female. Long-term regimen of purgative or diuretics was prescribed. The clinical features included normotension, hypokalemic alkalosis and activation of renin-angiotensin-aldosterone. The pathological results of 3 cases of kidney biopsy showed the hyperplasia of juxtaglomerular apparatus, thickness of arteriole, infiltration of lymphocytes and monocytes and degeneration of renal tubule. Upon a definitive diagnosis, purgative or diuretics was discontinued and supplement therapy of potassium chloride initiated. The results of laboratory tests reverted to normal ranges within 4 weeks.
  
  
  CONCLUSIONS
  Purgative or diuretics should be prescribed appropriately to avoid the occurrence of Pseudo-Bartter's syndrome.
authors.affiliation: Department of Endocrinology, Tianjin Medical University General Hospital, Tianjin 300052, China.
authors.forename: Feng-Ao
authors.initials: FA
authors.lastname: Li
authors.forename: Hong-Yan
authors.initials: HY
authors.lastname: Wei
authors.forename: Shan
authors.initials: S
authors.lastname: Lin
authors.forename: Hong-Ling
authors.initials: HL
authors.lastname: Han
authors.forename: Ming-Cai
authors.initials: MC
authors.lastname: Qiu
mesh_terms: D000328:Adult; D001477:Bartter Syndrome / Q000139:chemically induced* / Q000175:diagnosis; D002400:Cathartics / Q000009:adverse effects*; D004232:Diuretics / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D002400:Cathartics; D004232:Diuretics