title: Tissue response to experimental dental cements prepared from a modified powder glass composition.
abstract: The present work seeks to evaluate the biocompatibility of experimental glass ionomer cements (GIC) prepared from niobium-calcium fluoro-alumino-silicate glass powder and two commercial GICs. The GICs were implanted into the subcutaneous connective tissue of sixty rats. The rats were sacrificed during four varying time periods: 7, 15, 30, and 60 days and histopathological examinations were then performed. The Kruskal-Wallis test was performed to evaluate any significant differences between the materials. Additionally, multiple comparisons of the mean rank were also carried out using the Dunn test (p<0.05). No significant differences were observed that one GIC was superior to the other. The tissue response for all of the GICs tested was similar in all the periods examined.
authors.affiliation: Department of Restorative Dentistry, University Estadual Paulista-UNESP, Araraquara School of Dentistry, Araraquara, SP, Brazil. juboav@yahoo.com.br
authors.forename: Juliana Maria Capelozza
authors.initials: JM
authors.lastname: Boaventura
authors.forename: Marcio José
authors.initials: MJ
authors.lastname: Bertolini
authors.forename: Gislaine Cristina
authors.initials: GC
authors.lastname: Padovani
authors.forename: Maria Rita Brancini
authors.initials: MR
authors.lastname: de Oliveira
authors.forename: Maria Aparecida
authors.initials: MA
authors.lastname: Zaghete
authors.forename: Osmir Batista
authors.initials: OB
authors.lastname: de Oliveira Júnior
authors.forename: Marcelo Ferrarezi
authors.initials: MF
authors.lastname: de Andrade
mesh_terms: D017607:Aluminum Compounds; D000818:Animals; D001672:Biocompatible Materials; D002118:Calcium; D005459:Fluorides; D005899:Glass Ionomer Cements / Q000737:chemistry* / Q000494:pharmacology*; D008297:Male; D009556:Niobium; D011208:Powders / Q000494:pharmacology; D051381:Rats; D017655:Silicon Compounds; D040521:Subcutaneous Tissue / Q000187:drug effects*
chemical_list: D017607:Aluminum Compounds; D001672:Biocompatible Materials; D005899:Glass Ionomer Cements; D011208:Powders; D017655:Silicon Compounds; D009556:Niobium; C020328:fluoroaluminum silicate; D005459:Fluorides; D002118:Calcium