[Impact of CT/MRI image registration on target delineation of radiotherapy for lung cancer with brain metastasis].
BACKGROUND
Accurate target delineation in radiation therapy is a key component of the treatment regimen for brain metastasis for which CT/MRI fusion technology provides a feasible method. The aim of this study is to explore the role of CT/MRI image registration in target delineation for lung cancer with brain metastasis.


METHODS
The image data of 31 patients were processed using Oncentra MasterPlan. The GTVs were delineated on CT and CT/MRI images, and their differences were compared to analyze the impact of the maximum average error and tumor edema on target delineation.


RESULTS
The GTVs delineated on CT/MRI images were markedly smaller than those delineated on CT images. Target delineation was clearly influenced by edema.


CONCLUSIONS
The technology of CT/MRI image registration can improve the accuracy of target delineation for lung cancer with brain metastasis.
Department of Radiotherapy, the Third Affiliated Hospital of Harbin Medical University, Harbin 150081, China.
Yang
Y
Li
Xianglan
X
Li
Yewei
Y
Wang
Yang
Y
Zhou
D000368:Aged; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000556:secondary*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008175:Lung Neoplasms / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D061089:Radiotherapy, Image-Guided / Q000379:methods*; D014057:Tomography, X-Ray Computed