Porous membrane structures as stationary phase for capillary electrochromatography.
This work presents the application of membrane technology for the fabrication of stationary phase for CEC columns using the technique based on phase inversion of polymer solution. A blend of polyimide P84 and sulphonated poly(ether ether ketone was processed via immersion precipitation dry-wet spinning into small-bore porous fiber. The morphology, zeta potential, and performance of the porous structure in the CEC separation were investigated. Noncharged molecules (as markers of the electroosmotic flow) and small organic compounds were injected into the column, driven under the application of voltage, and detected on the electropherogram. The proof of concept of applying porous membrane structure as stationary phase for CEC was shown and possible optimization to improve efficiency and selectivity was suggested.
Institute for Biomedical Technology and Technical Medicine, University of Twente, AE Enschede, The Netherlands.
Karina K
KK
Kopeć
Matthias
M
Wessling
Dimitrios F
DF
Stamatialis
D053801:Capillary Electrochromatography / Q000295:instrumentation* / Q000379:methods*; D008567:Membranes, Artificial; D009930:Organic Chemicals / Q000737:chemistry / Q000302:isolation & purification; D011108:Polymers / Q000737:chemistry; D016062:Porosity
D008567:Membranes, Artificial; D009930:Organic Chemicals; D011108:Polymers