Taurine and central nervous system disorders.
In the present era, investigators seek to find therapeutic interventions that are multifaceted in their mode of action. Such targets provide the most advantageous routes for addressing the multiplicity of pathophysiological avenues that lead to neuronal dysfunction and death observed in neurological disorders and neurodegenerative diseases. Taurine, an endogenous amino acid, exhibits a plethora of physiological functions in the central nervous system. In this review, we describe the mode of action of taurine and its clinical application in the neurological diseases: Alzheimer's disease, Parkinson's disease and Huntington's disease.
Program in Integrative Biology, Florida Atlantic University, Boca Raton, FL, 33431, USA, jmenzie@fau.edu.
Janet
J
Menzie
Chunliu
C
Pan
Howard
H
Prentice
Jang-Yen
JY
Wu
D000818:Animals; D002490:Central Nervous System / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D019636:Neurodegenerative Diseases / Q000378:metabolism* / Q000401:mortality / Q000473:pathology; D013654:Taurine / Q000378:metabolism*
D013654:Taurine