Multilayered shell SERS nanotags with a highly uniform single-particle Raman readout for ultrasensitive immunoassays.
Novel SERS nanotags with highly uniform and reproducible signals have been developed by the layer-by-layer assembly and crosslinkage of small silver nanoparticles at the surface of silica particles, which opens an avenue to the quantitative and reliable SERS application in bioassays.
Institute of Intelligent Machines, Chinese Academy of Sciences, Hefei, Anhui 230031, China.
Renyong
R
Liu
Bianhua
B
Liu
Guijian
G
Guan
Changlong
C
Jiang
Zhongping
Z
Zhang
D014408:Biomarkers, Tumor / Q000097:blood / Q000737:chemistry; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D053768:Metal Nanoparticles / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013438:Sulfhydryl Compounds / Q000737:chemistry; D013499:Surface Properties
D014408:Biomarkers, Tumor; D013438:Sulfhydryl Compounds; D012834:Silver