New precursor of tetraterpenoids from the soft coral Sarcophyton glaucum.
One new precursor of tetraterpenoids, Sarglaucol (1), along with eight known compounds have been isolated from the soft coral Sarcophyton glaucum collected from the Sanya Bay, Hainan Island, China. Their structures were elucidated through spectroscopic techniques including 1D- and 2D-NMR, and their relative configurations were also assigned by NMR and NOESY analysis. Compounds 1 showed weak antitumour activities.
School of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou 510006, PR China. zhangcuixian@yahoo.com.cn
Cui-Xian
CX
Zhang
Xi-Xin
XX
He
Jun
J
Zhang
Qiong
Q
Guo
Ling-Fang
LF
Lei
Jing-Yu
JY
Su
Long-Mei
LM
Zeng
D000818:Animals; D037421:Anthozoa / Q000737:chemistry* / Q000378:metabolism; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor / Q000187:drug effects; D002681:China; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013729:Terpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
D000970:Antineoplastic Agents; D013729:Terpenes; C585507:sarglaucol