The role of hyaluronan in wound healing.
The polysaccharide hyaluronan (HA) (synonyms - hyaluronic acid, hyaluronate) is a versatile, polymorphic, glycosoaminoglycan with vast biological functions. HA is found throughout the body, primarily residing in skin, thus playing an important role in wound healing. Research regarding HA's function has changed over the years, primarily focussing on a particular aspect or function. The contribution of HA in each stage of normal wound healing as well as its clinical wound dressing applications will be examined.
Wound Healing Research Unit, Department of Wound Healing, School of Medicine, Cardiff University, Melbourne, Victoria, Australia.
Joseph S
JS
Frenkel
D000276:Adjuvants, Immunologic / Q000737:chemistry / Q000502:physiology*; D020405:Dermis / Q000166:cytology; D000078404:Epidermal Cells; D006097:Granulation Tissue / Q000502:physiology; D006801:Humans; D006820:Hyaluronic Acid / Q000737:chemistry / Q000502:physiology*; D007249:Inflammation / Q000503:physiopathology; D062326:Re-Epithelialization / Q000502:physiology*; D014945:Wound Healing / Q000502:physiology*
D000276:Adjuvants, Immunologic; D006820:Hyaluronic Acid