Benzimidazole-based anion receptors exhibiting selectivity for lactate over pyruvate.
The influence of anions on tautomerism in benzimidazole containing anion receptors has been studied via a variety of techniques in both solution and the solid state. The results show that hydrogen bonding interactions between the receptors and guests have a significant effect of the nature of the tautomer present. The compounds show a preference for complexation of lactate over pyruvate.
Chemistry, University of Southampton, Southampton, SO17 1BJ, UK.
Jennifer R
JR
Hiscock
Philip A
PA
Gale
Noémie
N
Lalaoui
Mark E
ME
Light
Neil J
NJ
Wells
D000838:Anions / Q000737:chemistry; D001562:Benzimidazoles / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D019344:Lactic Acid / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D019289:Pyruvic Acid / Q000737:chemistry*; D014508:Urea / Q000031:analogs & derivatives / Q000138:chemical synthesis* / Q000737:chemistry
D000838:Anions; D001562:Benzimidazoles; D007211:Indoles; D019344:Lactic Acid; D019289:Pyruvic Acid; D014508:Urea; C031000:benzimidazole