Palladium-catalyzed synthesis of 2,3,4-trisubstituted furans via cascade reactions of aryloxy-enynes with aryl halides.
A highly efficient palladium-catalyzed cascade reactions of aryloxy-enynes with aryl halides under mild reaction conditions has been developed. This methodology offers rapid access to 2,3,4-trisubstituted furans in good to excellent yields in a regioselective manner.
Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 500 Dongchuan Road, Shanghai, 200241, People's Republic of China.
Ende
E
Li
Xingcan
X
Cheng
Chengyu
C
Wang
Yushang
Y
Shao
Yanzhong
Y
Li
D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D004987:Ethers / Q000737:chemistry*; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
D000480:Alkynes; D004987:Ethers; D005663:Furans; D006846:Hydrocarbons, Halogenated; D009942:Organometallic Compounds; D010165:Palladium