Biogenetic-type synthesis of 2-hydroxy-4,4,7-trimethyl-1(4H)-naphthalenone, a modified apocarotenoid from Ipomoea pes-caprae.
A biogenetic-type synthesis of 2-hydroxy-4,4,7-trimethyl-1(4H)-naphthalenone (1), a modified apocarotenoid isolated from Ipomoeapes-caprae (Linn.) R. Br. showing anti-inflammatory activity by inhibiting prostaglandin synthesis in vitro, is described. A biogenetic proposal for the natural occurrence of 1 is also presented.
Department of Chemistry, Goa University, Goa, 403206, India.
Kamalesh P Pai
KP
Fondekar
Shashikumar K
SK
Paknikar
Savia
S
Torres
Shrivallabh P
SP
Kamat
D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis* / Q000737:chemistry*; D002338:Carotenoids / Q000737:chemistry*; D027741:Ipomoea / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*
D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; D002338:Carotenoids