Hypercrosslinked strong anion-exchange resin for extraction of acidic pharmaceuticals from environmental water.
Two novel high-specific surface area polymeric sorbents (HXLPP-SAXa and HXLPP-SAXb) were synthesised and evaluated as solid-phase extraction sorbents. The novel sorbents under study are based on hypercrosslinked polymer microspheres and designed specifically to offer ion-exchange properties; the specific polymers of interest in the current work have been chemically modified in such a way as to impart a tuneable level of strong anion-exchange character onto the sorbents. The novel sorbents were applied as strong anion-exchange sorbents in solid-phase extraction studies, with the goal being to selectively extract a group of acidic compounds from complex environmental samples in an efficient manner. Out of two HXLPP-SAX resins evaluated in this study, it was found that the sorbent with the lower ion-exchange capacity (HXLPP-SAXa) gave rise to the best overall performance characteristics and, indeed, was found to compare favourably to the solid-phase extraction performance of commercial strong anion-exchange sorbents. When the HXLPP-SAXa sorbent was applied to the solid-phase extraction of environmental water samples, the result showed quantitative and selective extraction of low levels of acidic pharmaceuticals from 500 mL of river water and 100 mL of effluent wastewater.
Departament de Química Analítica i Química Orgànica, Universitat Rovira i Virgili, Tarragona, Spain.
Dominika
D
Bratkowska
Arlene
A
Davies
Núria
N
Fontanals
Peter A G
PA
Cormack
Francesc
F
Borrull
David C
DC
Sherrington
Rosa M
RM
Marcé
D000327:Adsorption; D000837:Anion Exchange Resins / Q000737:chemistry*; D003432:Cross-Linking Reagents / Q000737:chemistry; D004364:Pharmaceutical Preparations / Q000737:chemistry* / Q000302:isolation & purification; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000737:chemistry* / Q000302:isolation & purification
D000837:Anion Exchange Resins; D003432:Cross-Linking Reagents; D004364:Pharmaceutical Preparations; D014874:Water Pollutants, Chemical