[Clinical analysis of the application of R.E.N.A.L. nephrometry score for the nephron sparing surgery].
OBJECTIVE
To investigate the clinical significance of R.E.N.A.L. nephrometry score for renal neoplasms in patients undergoing nephron sparing  surgery.


METHODS
A retrospective analysis was conducted of clinical data of 110 patients with renal neoplasms undergoing nephron sparing surgery,  who were admitted to Peking University First Hospital from January 2010 to January 2012. The operation approaches, perioperative variables and  perioperative complications as well as R.E.N.A.L. scores were compared.


RESULTS
The R.E.N.A.L. nephrometry score was significantly associated with  the operation approach (P<0.001), while there was no significant association between the scoring system and the occurrence of complications (P<0.611).  Meanwhile, it was associated with ischemia time (P<0.023) and percentage change in the creatinine level (P<0.025). Low complexity tumors had  significantly shorter ischemia time and low percentage change in the creatinine level than high complexity tumors (P<0.008, P<0.010). Fleiss' generalized  kappa was 0.52 to 0.89 for the R.E.N.A.L. nephrometry components.


CONCLUSIONS
The R.E.N.A.L. nephrometry score is a comprehensive assessment  tool for delineating renal tumor anatomy. The reproducibility of R.E.N.A.L. nephrometry scores is substantial, but further research is required to evaluate its  performance in predicting operative outcomes more accurately.
Department of Urology, Peking University First Hospital, Beijing, China.
Zhong-yuan
ZY
Zhang
Qi
Q
Tang
Xue-song
XS
Li
Jing-yun
JY
Wu
Xue-dong
XD
Yang
Xiao-chun
XC
Zhang
Xiao-ying
XY
Wang
Li-qun
LQ
Zhou
D000328:Adult; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000009:adverse effects / Q000379:methods*; D009399:Nephrons; D059351:Organ Sparing Treatments / Q000379:methods*; D011237:Predictive Value of Tests