Neural correlates of recovery from Foix-Chavany-Marie syndrome.
Cerebral reorganization during recovery after stroke has been investigated using functional imaging in patients with subcortical motor stroke. The functional correlates of recovery from anarthria, however, are yet unknown. A 48-year-old male patient recovering from complete anarthria after unilateral right-sided subcortical hemorrhagic stroke is described. The main outcome measures included clinical and neuroimaging data at three different time points (at the onset of symptoms, after 6 weeks and after 6 months). At 6 weeks, increased activations in the right and left frontal operculum were found and were followed by a trend towards normalization of the activation pattern at 6 months. These results suggest a role of anterior opercular regions in recovery from anarthria after subcortical stroke. Moreover, complete recovery is possible after such lesions.
Department of Neurosurgery, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium. tom.theys@med.kuleuven.be
Tom
T
Theys
Sofie
S
Van Cauter
Kuan H
KH
Kho
Anne-Catherine
AC
Vijverman
Ronald R
RR
Peeters
Stefan
S
Sunaert
Johannes
J
van Loon
D001931:Brain Mapping; D002540:Cerebral Cortex / Q000098:blood supply / Q000000981:diagnostic imaging / Q000503:physiopathology*; D003680:Deglutition Disorders / Q000473:pathology* / Q000503:physiopathology*; D004401:Dysarthria / Q000175:diagnosis / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology*; D004673:Encephalomyelitis, Acute Disseminated / Q000473:pathology* / Q000503:physiopathology*; D005158:Facial Paralysis / Q000473:pathology* / Q000503:physiopathology*; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010100:Oxygen / Q000097:blood; D011578:Psycholinguistics; D011859:Radiography; D015898:Tomography Scanners, X-Ray Computed
D010100:Oxygen