Salmonella mycotic aneurysm: a rare cause of fever and back pain in elderly.
An 85-year-old man with history of hypertension presented with fever, cough and abdominal pain. Unfortunately fever and leukocytosis persisted despite treatment. Blood cultures obtained on admission grew Salmonella enteritidis. Subsequently he developed increasing back pain and transoesophageal echocardiography (TOE) was performed, demonstrating a complex ulcer at the aortic arch with multiple small mobile strandlike densities suggestive of vegetation. Contrast thoracic CT scan confirmed an ulcerated atherosclerotic plaque which progressively increasing in size over 3 months despite antibiotics. Therefore, a stent was deployed in view of high risk of perforation and he was placed on prolonged antibiotics. Post-stenting CT scan a few months later showed a patent stent with the aneurysm remained stable in size. Cardiovascular infections develop in approximately 25 % of patients with Salmonella bacteremia. Most patients with Salmonella aortitis have preexisting atherosclerosis at the site of the subsequently infected aneurysm. The diagnosis of S. aortitis can be challenging, because the clinical course may be indolent and the symptoms are nonspecific. A high index of suspicion is required to make the diagnosis of S. aortitis, especially in patients with Salmonella bacteraemia, fever, back pain and/or abdominal pain. This case highlights the usefulness of TOE in the evaluation of diseases involving the thoracic aorta, leading to a successful intervention.
Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong, China. ljl517@yahoo.co.nz
Jen-Li
JL
Looi
Lily
L
Cheung
Alex Pui-Wai
AP
Lee
D000369:Aged, 80 and over; D000785:Aneurysm, Infected / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017545:Aortic Aneurysm, Thoracic / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D001025:Aortitis / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D001027:Aortography / Q000379:methods; D050197:Atherosclerosis / Q000150:complications; D001416:Back Pain / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation; D017548:Echocardiography, Transesophageal; D005334:Fever / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D012480:Salmonella Infections / Q000150:complications / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D012477:Salmonella enteritidis / Q000302:isolation & purification*; D015607:Stents; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents