Palladium-catalyzed dehydrogenative β'-arylation of β-keto esters under aerobic conditions: interplay of metal and Brønsted acids.
The Brønsted aids: The first dehydrogenative arylation of β-keto esters with arenes under ambient aerobic conditions is described. Under a Pd(II)/Brønsted acid co-catalytic system, regioselective arylations with alkoxylated arenes and phenols were achieved in good yields, even in gram-scale conditions.
Department of Chemistry, University of Jyväskylä, Finland.
Kai-Tai
KT
Yip
Roshan Y
RY
Nimje
Mikko V
MV
Leskinen
Petri M
PM
Pihko