Psychometric evaluation of the Taiwan Chinese version of the EORTC QLQ-PR25 for HRQOL assessment in prostate cancer patients.
OBJECTIVE
To evaluate the psychometric properties of the Taiwan Chinese Version of the EORTC QLQ-PR25 health-related quality of life (HRQOL) questionnaire for patients with prostate cancer.


METHODS
135 prostate cancer patients were recruited in the urology outpatient clinic of a university teaching hospital. Each patient completed the EORTC QLQ-PR25 at every clinic visit between 2004 and 2008, totaling 633 assessments. Confirmatory factor analysis and Rasch analysis were used to evaluate the domain- and item-level psychometric properties.


RESULTS
The results supported the unidimensionality of each of the four EORTC QLQ-PR25 domains (urinary, bowel, and hormonal-treatment-related symptoms, and sexual functioning). Item calibrations for each domain were found invariant across the three assessment time periods. The item-person maps showed 71.3% of item coverage for the urinary symptoms domain and 13-42.7% for the other three domains.


CONCLUSIONS
The Taiwan Chinese Version of the EORTC QLQ-PR25 questionnaire is reliable and can be used to measure HRQOL over time. Adding new items to each domain may improve its clinical content coverage and measurement precision.
Graduate Institute of Public Health, China Medical University, Taichung, Taiwan.
Yu-Jun
YJ
Chang
Wen-Miin
WM
Liang
Hsi-Chin
HC
Wu
Hsueh-Chun
HC
Lin
Jong-Yi
JY
Wang
Tsai-Chung
TC
Li
Yi-Chun
YC
Yeh
Chih-Hung
CH
Chang
D000368:Aged; D000369:Aged, 80 and over; D005163:Factor Analysis, Statistical; D005260:Female; D015577:Geriatric Assessment / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D055496:Neurogenic Bowel / Q000150:complications; D017063:Outcome Assessment, Health Care / Q000379:methods; D011471:Prostatic Neoplasms / Q000523:psychology*; D011594:Psychometrics / Q000379:methods*; D019984:Quality Indicators, Health Care; D011788:Quality of Life; D015203:Reproducibility of Results; D012735:Sexual Dysfunction, Physiological / Q000150:complications; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D013624:Taiwan; D014175:Translating; D016896:Treatment Outcome; D014549:Urinary Incontinence / Q000150:complications