Epidemiological evaluation of breast cancer in ecological areas of Kazakhstan--association with pollution emissions.
The aim of the research was to evaluate the incidence of breast cancer in the ecological areas of Kazakhstan and assess the potential . A retrospective study of 11 years (1999 to 2009) was conducted using descriptive and analytical methods. The incidence of breast cancer was the lowest in the Aral-Syr Darya area (18.6±0.80/100,000), and highest in the Irtysh area (48.9±1.90/100,000), with an increasing trends over time in almost all areas. A direct strong correlation between the degree of contamination with high pollution emissions in the atmosphere from stationary sources and the incidence of breast cancer (r=0.77±0.15; p=0.026). The results indicate an increasing importance of breast cancer in Kazakhstan and an etiological role for environmental pollution.
Central Asia Cancer Institute, Astana, Kazakhstan.
Zarina
Z
Bilyalova
Nurbek
N
Igissinov
Malcolm
M
Moore
Saginbek
S
Igissinov
Samal
S
Sarsenova
Zauresh
Z
Khassenova
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000209:etiology*; D004463:Ecology; D004785:Environmental Pollutants / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007623:Kazakhstan / Q000453:epidemiology; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies
D004785:Environmental Pollutants