Thyroid-like follicular carcinoma of the kidney: report of two cases with detailed immunohistochemical profile and literature review.
Thyroid-like follicular carcinoma of the kidney (TLFC) is an unusual histological variant of renal cell carcinoma not included in the current WHO classification of renal tumors. Its morphological features resemble a large spectrum of benign and malignant renal and extra-renal conditions which should be ruled out in the diagnostic process. Because TLFC outcome is different from the other variants of renal cell carcinoma, the exploration for disease-specific markers is mandatory. The aim of the present paper is to illustrate the histological characteristics and immunohistochemical profile of two new cases along with a brief review of the literature.
Department of Medicine, Surgical Pathology and Cytopathology Unit, University Hospital of Padua, Via Aristide Gabelli, 61-35121 Padua (PD), Italy.
Lara
L
Alessandrini
Matteo
M
Fassan
Marina Paola
MP
Gardiman
Andrea
A
Guttilla
Fabio
F
Zattoni
Tommaso Prayer
TP
Galletti
Filiberto
F
Zattoni
D018263:Adenocarcinoma, Follicular / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000378:metabolism; D002292:Carcinoma, Renal Cell / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D008297:Male; D009392:Nephrectomy; D025321:Surgery, Computer-Assisted; D013964:Thyroid Neoplasms / Q000378:metabolism / Q000473:pathology; D016896:Treatment Outcome
D014408:Biomarkers, Tumor