Fitness and cognitive processing speed in persons with multiple sclerosis: a cross-sectional investigation.
This cross-sectional study examined associations among aerobic capacity, muscle strength, balance, and cognitive processing speed (CPS) in 31 persons with multiple sclerosis (MS) and 31 matched controls. Participants completed neuropsychological tests and aerobic capacity (i.e., peak oxygen consumption), muscular strength (i.e., asymmetry between knee muscles), and balance (i.e., postural sway) assessments. Aerobic capacity (r = .27), postural sway (r = -.40), and knee extensor asymmetry (r = -.25) were associated with CPS in those with MS and accounted for differences in CPS between MS and control groups. Such cross-sectional data suggest that aerobic, balance, and resistance training might be avenues for improving CPS in this population.    The authors report no conflicts of interest and thank Swathi Balantrapu, Jason Silberman, Stefanie Fitterer, and Rachel Japp for assistance in data acquisition.
Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Brian M
BM
Sandroff
Robert W
RW
Motl
D000328:Adult; D001835:Body Weight / Q000502:physiology; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D003430:Cross-Sectional Studies; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications*; D009483:Neuropsychological Tests; D010101:Oxygen Consumption; D010809:Physical Fitness / Q000502:physiology*; D004856:Postural Balance; D012044:Regression Analysis; D055070:Resistance Training / Q000379:methods