BET 1: should tranexamic acid be given to patients who are having an upper gastrointestinal bleed?
A short cut review was carried out to establish whether tranexamic acid should be given to patients having an upper gastrointestinal bleed. Seven studies and two systematic reviews were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. The clinical bottom line is that there is insufficient evidence, at the moment, to recommend the use of tranexamic acid in the management of upper gastrointestinal bleeding.
Royal Free Hospital, London, UK.
Anna
A
Morgan
Anna
A
Jeffrey-Smith
D000328:Adult; D000933:Antifibrinolytic Agents / Q000627:therapeutic use*; D004636:Emergency Service, Hospital; D055416:Evidence-Based Emergency Medicine; D006396:Hematemesis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008297:Male; D014148:Tranexamic Acid / Q000627:therapeutic use*; D006113:United Kingdom
D000933:Antifibrinolytic Agents; D014148:Tranexamic Acid