Nutritional support in acute pancreatitis.
Acute pancreatitis can present as a mild or severe disease. Most patients have a mild disease and recover without requiring nutritional support. Patients with severe acute pancreatitis may develop systemic inflammatory response syndrome and progress to multi-organ failure. These ill patients have high metabolism and protein catabolism. Hence, the nutritional management of these patients can be challenging. The aim of nutritional support is to meet the elevated metabolic demands as far as possible without stimulating pancreatic secretion and yet maintaining the gut integrity. The concept of pancreatic rest has evolved over the years. To date, there is a substantial scientific proof that enteral nutrition (EN) in comparison to parenteral nutrition significantly reduces infectious complications, surgical interventions and mortality in predicted severe acute pancreatitis. EN may be able to improve outcome in these patients if given early. In this review, we summarized the current knowledge on nutrition in acute pancreatitis and shared our local experience.
Department of Gastroenterology, Changi General Hospital, Singapore. jeannie_ong@cgh.com.sg
Jeannie P L
JP
Ong
Kwong Ming
KM
Fock
D000208:Acute Disease; D004750:Enteral Nutrition; D006801:Humans; D018529:Nutritional Support; D010195:Pancreatitis / Q000628:therapy*; D010288:Parenteral Nutrition