The impact of structural biology on alkaloid biosynthesis research.
In the recent past, macromolecular crystallography has gone through substantial methodological and technological development. The purpose of this review is to provide a general overview of structural biology and its impact on enzyme structure/function analysis and illustrate how it is modifying the focus of research relevant to alkaloid biosynthesis.
Australian Synchrotron, 800 Blackburn Road, Clayton, Victoria 3168, Australia. santosh.panjikar@synchrotron.org.au
Santosh
S
Panjikar
Joachim
J
Stoeckigt
Sarah
S
O'Connor
Heribert
H
Warzecha
D000470:Alkaloids / Q000096:biosynthesis* / Q000737:chemistry; D008025:Ligases / Q000378:metabolism*; D008516:Medicine, Chinese Traditional; D008958:Models, Molecular; D058977:Molecular Sequence Annotation; D015394:Molecular Structure
D000470:Alkaloids; D008025:Ligases