[The Kleine-Levin syndrome and the treatment with methylphenidate].
A 17-year-old man was referred to the Med-Psych-Unit because of recurrent episodes of hypersomnia, megaphagia, hypersexual behaviour and cognitive disturbances. Over the period of three years he suffered more than 10 episodes of hypersomnia each lasting 8 to 16 days. The clinical presentation was suggestive of the Kleine-Levin syndrome. The symptoms disappeared after treatment with methylphenidate, but it was not clear whether this could be attributed to the medication or to the self-limiting character of the illness. The Kleine-Levin syndrome is often clinically not recognised due to the variation in the symptoms and the lack of objective diagnostic examination.
Maastricht Universitair Medisch Centrum.
S H A
SH
Brouns
J
J
Schieveld
C
C
Leue
D000293:Adolescent; D000697:Central Nervous System Stimulants / Q000627:therapeutic use*; D006801:Humans; D017593:Kleine-Levin Syndrome / Q000188:drug therapy*; D008297:Male; D008774:Methylphenidate / Q000627:therapeutic use*; D012008:Recurrence; D016896:Treatment Outcome
D000697:Central Nervous System Stimulants; D008774:Methylphenidate