Simultaneous low (1 Hz)- and high (10 Hz)-frequency bilateral transcranial magnetic stimulation in a patient with severe depression and crohn disease.
We present a case report in which electroconvulsive therapy had a good effect for the treatment of depression in association with Crohn disease, but adverse effects limited its use. Repetitive transcranial magnetic stimulation was tried both in a conventional way (high frequency over the left dorsolateral prefrontal cortex) and in a bilateral sequential way (high frequency in the same region followed in the same session by low frequency on the right side). Finally, bilateral simultaneous stimulation (high frequency over the left and low frequency over the right side) was tried and resulted in a response similar to that of electroconvulsive therapy.
Federal University of São Paulo, Sao Paulo, Brazil. moarosa@ipan.med.br
Moacyr Alexandro
MA
Rosa
Marco Aurelio
MA
Andrade
Guilherme Lozi
GL
Abdo
Marina Odebrecht
MO
Rosa
D000328:Adult; D003424:Crohn Disease / Q000150:complications*; D003865:Major Depressive Disorder / Q000150:complications* / Q000628:therapy*; D005260:Female; D006801:Humans; D017397:Prefrontal Cortex / Q000502:physiology; D050781:Transcranial Magnetic Stimulation