Synthesis of indoles through highly efficient cascade reactions of sulfur ylides and N-(ortho-chloromethyl)aryl amides.
Batting the ylides: A simple procedure carried out under mild conditions allows the direct and efficient synthesis of structurally diverse indoles. This approach involves a cascade reaction of sulfur ylides and N-(ortho-chloromethyl)aryl amides.
Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan, Hubei 430079, China.
Qing-Qing
QQ
Yang
Cong
C
Xiao
Liang-Qiu
LQ
Lu
Jing
J
An
Fen
F
Tan
Bin-Jie
BJ
Li
Wen-Jing
WJ
Xiao
D000577:Amides / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry*; D009584:Nitrogen / Q000737:chemistry; D013455:Sulfur / Q000737:chemistry*
D000577:Amides; D006571:Heterocyclic Compounds; D007211:Indoles; D013455:Sulfur; D009584:Nitrogen