A role of genomic copy number variation in the complex behavioral phenotype of alcohol dependence: a commentary.
In their paper "Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence" Lin and colleagues report on the association between alcohol dependence and 2 duplication CNVs in the genome sequence, one containing 8 genes within its boundaries and another that contains no genes. In this commentary, I point out some of the opportunities and challenges that arise from such a finding.
Department of Psychiatry and Behavioral Sciences, Department of Genetics, Stanford University School of Medicine, Palo Alto, California, USA. aeurban@stanford.edu
Alexander E
AE
Urban
D000437:Alcoholism / Q000235:genetics*; D056915:DNA Copy Number Variations; D005260:Female; D006801:Humans; D008297:Male