An alternative one-pot gold-catalyzed approach to the assembly of 11H-indolo[3,2-c]quinolines.
A new one-pot approach was developed to construct the 11H-indolo[3,2-c]quinoline scaffold through a gold-catalysed reaction of 2-[(2-aminophenyl)ethynyl]phenylamine derivatives with aldehydes. The broad scope and the high regioselectivity of this new protocol as well as the mild and neutral reaction conditions make it a viable alternative to the previously reported procedures.
Dipartimento di Scienze Farmaceutiche-Sezione di Chimica generale e Organica A. Marchesini, Università degli Studi di Milano, Via G. Venezian 21, 20133 Milano, Italy.
Giorgio
G
Abbiati
Antonio
A
Arcadi
Marco
M
Chiarini
Fabio
F
Marinelli
Emanuela
E
Pietropaolo
Elisabetta
E
Rossi
D002384:Catalysis; D006046:Gold / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D050607:Organogold Compounds / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D007211:Indoles; D050607:Organogold Compounds; D011804:Quinolines; D006046:Gold