Congenital and neonatal lupus erythematosus: two case reports.
Neonatal lupus erythematosus is an autoimmune disease produced by the passage of maternal antinuclear antibodies and extractable nuclear antigen antibodies through the placenta. At the moment of the diagnosis, the mothers are asymptomatic in 40 to 60% of cases. The most common manifestations are cutaneous lesions and congenital heart block. The cutaneous findings are variable and usually begin within the first weeks or months of life. Congenital lupus erythematosus is a congenital variant of neonatal lupus erythematosus. We present one case of congenital lupus erythematosus and one case of neonatal lupus erythematous, showing the variability of this disease.
Dermatology Service, Federal University of Health Sciences, Porto Alegre, RS, Brazil.
Marcos Noronha
MN
Frey
Ana Elisa Empinotti
AE
Ioppi
Gabriela Czarnobay
GC
Garbin
Roque Domingos
RD
Furian
Ana Elisa Kiszewski
AE
Bau
D000974:Antibodies, Antinuclear / Q000097:blood; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis; D008178:Lupus Erythematosus, Cutaneous / Q000151:congenital* / Q000175:diagnosis; D012075:Remission, Spontaneous
D000974:Antibodies, Antinuclear; C035356:SS-A antibodies; C035357:SS-B antibodies