Genome sequence of a waterfowl aviadenovirus, goose adenovirus 4.
We present, to our knowledge, the first complete genome sequence of a waterfowl aviadenovirus, goose adenovirus (GoAdV) strain P29, and an analysis of its genetic content in comparison with five published aviadenovirus genome sequences. Of the 35 genes predicted to encode functional proteins, the central region of the genome contains 19 (IVa2 to fiber-2) that were inherited from the ancestor of all known adenoviruses. Of the remaining genes, nine have orthologues only in aviadenoviruses and seven lack orthologues in any adenovirus. We also obtained limited sequence data for a pathogenic GoAdV strain D1036/08. Phylogenetic analyses placed the two GoAdV strains monophyletically in the genus Aviadenovirus. We propose designating strains P29 and D1036/08 as GoAdV-4 and GoAdV-5, respectively.
Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, PO Box 18, H-1581 Budapest, Hungary.
Győző L
GL
Kaján
MRC - University of Glasgow Centre for Virus Research, 8 Church Street, Glasgow, G11 5JR, UK.
Andrew J
AJ
Davison
CEVA-Phylaxia Inc., Szállás u. 5, H-1107 Budapest, Hungary.
Vilmos
V
Palya
Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, PO Box 18, H-1581 Budapest, Hungary.
Balázs
B
Harrach
Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences, PO Box 18, H-1581 Budapest, Hungary.
Mária
M
Benkő
D000257:Adenoviridae Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D000818:Animals; D046090:Anseriformes / Q000821:virology*; D000259:Aviadenovirus / Q000145:classification* / Q000235:genetics*; D001715:Bird Diseases / Q000453:epidemiology / Q000821:virology*; D015967:Gene Expression Regulation, Viral; D016679:Genome, Viral; D006814:Hungary / Q000453:epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism
D014764:Viral Proteins