Structure elucidation and NMR assignments of an unusual aromatic monacolin analog from Monascus purpureus-fermented rice.
One unusual aromatic monacolin analog, aromonacolin A (1), was isolated from the ethanolic extract of Monascus purpureus-fermented rice. Its structure was elucidated by extensive spectroscopic (HRESIMS, (1)H NMR, (13)C NMR, HSQC, HMBC, and NOESY) and chemical methods. The absolute configuration of the C-6 secondary alcohol was deduced via the circular dichroism data of the in situ formed [Rh(2)(OCOCF(3))(4)] complex.
Ming-Tao
MT
Liu
Na
N
Luan
Jin-Jie
JJ
Li
Xiao
X
Huang
Ye-Feng
YF
Wang
A-Li
AL
Wang
Xiao-Ya
XY
Shang
D002942:Circular Dichroism; D005285:Fermentation; D006537:Heptanoates / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D032741:Monascus / Q000737:chemistry*; D009284:Naphthols / Q000737:chemistry*; D012275:Oryza / Q000737:chemistry*
D006537:Heptanoates; D009284:Naphthols