Palladium-catalyzed tandem allenyl and aryl C-N bond formation: efficient access to N-functionalized multisubstituted indoles.
An efficient palladium-catalyzed synthesis of N-functionalized multisubstituted indoles from easily accessible ortho-haloarylallenes and primary amines has been developed. A wide range of electronically and structurally varied nitrogen fragments could be introduced through this tandem C-N bond-forming process by tuning the reaction conditions.
Department of Chemistry, Shanghai University, Shanghai 200444, China.
Bingxin
B
Liu
Xiaohu
X
Hong
Dong
D
Yan
Shuguang
S
Xu
Xiaomei
X
Huang
Bin
B
Xu