Implementation of false discovery rate for exploring novel paradigms and trait dimensions with ERPs.
False discovery rate (FDR) is a multiple comparison procedure that targets the expected proportion of false discoveries among the discoveries. Employing FDR methods in event-related potential (ERP) research provides an approach to explore new ERP paradigms and ERP-psychological trait/behavior relations. In Study 1, we examined neural responses to escape behavior from an aversive noise. In Study 2, we correlated a relatively unexplored trait dimension, ostracism, with neural response. In both situations we focused on the frontal cortical region, applying a channel by time plots to display statistically significant uncorrected data and FDR corrected data, controlling for multiple comparisons.
Yale Child Study Center, Yale University, New Haven, Connecticut, USA. michael.crowley@yale.edu
Michael J
MJ
Crowley
Jia
J
Wu
Scott
S
McCreary
Kelly
K
Miller
Linda C
LC
Mayes
D000293:Adolescent; D001931:Brain Mapping / Q000379:methods*; D002648:Child; D004924:Escape Reaction / Q000502:physiology*; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D005625:Frontal Lobe / Q000502:physiology*; D006801:Humans; D008297:Male; D010551:Personality / Q000502:physiology*; D025341:Principal Component Analysis; D012107:Research Design; D055815:Young Adult