[Influence of the extract from tunic of purple ascidium sea hydrobiont on the lipid metabolism in liver under acute stress conditions].
The effect of an extract from tunic of the sea hydrobiont purple ascidium (Halocynthia aurantium) on the lipid metabolism in the liver of mice has been studied under the acute stress conditions modeled by fixing animals for 22 h at the dorsal neck fold. The extract from purple ascidium tunic is superior to essentiale (well-known commercial hepatoprotector) in the efficacy of restoring lipid fraction content (tryglycerides, cholesterol, free fat acids, lysophospholipids) disturbed by stress action. In addition, the extract normalizes the esterification function of the liver. The observed effect of the purple ascidium tunica extract is related to a combined action of the "marine" phospholipids that are present in the preparation and are known to possess reparative properties.
S E
SE
Fomenko
N F
NF
Kushnerova
E Iu
EIu
Dobriakov
D000818:Animals; D002784:Cholesterol / Q000032:analysis; D045424:Complex Mixtures / Q000008:administration & dosage* / Q000737:chemistry; D000431:Ethanol / Q000737:chemistry; D005230:Fatty Acids, Nonesterified / Q000032:analysis; D007103:Immobilization; D050356:Lipid Metabolism / Q000187:drug effects; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008246:Lysophospholipids / Q000032:analysis; D008297:Male; D051379:Mice; D010713:Phosphatidylcholines / Q000008:administration & dosage; D013312:Stress, Physiological / Q000187:drug effects*; D014280:Triglycerides / Q000032:analysis; D014561:Urochordata / Q000737:chemistry*
D045424:Complex Mixtures; D005230:Fatty Acids, Nonesterified; D008246:Lysophospholipids; D010713:Phosphatidylcholines; D014280:Triglycerides; C011246:essential 303 forte; D000431:Ethanol; D002784:Cholesterol