Risk factors for cognitive impairment in school-age children born preterm: application of a hierarchical model.
The purpose was to analyze factors associated with cognitive impairment in very low birth weight (VLBW) children born preterm. A prospective cohort of 65 VLBW children was assessed at the age of eight years using the Wechsler Intelligence Scale for Children. A model for the relationship of variables with the cognitive impairment outcome attributed hierarchical levels: distal (socioeconomic variables), intermediate I and II (perinatal and neonatal variables, post-neonatal variables) and proximal (child health and psychosocial stimulation). A multivariate logistic regression was performed. In the multivariate hierarchical logistic regression, the maternal education (OR=0.77, 95%CI 0.63-0.94) and number of prenatal visits (OR=0.73, 95%CI 0.54-0.99) showed a protective association, but the male (OR=7.3, 95%CI 1.54-35.3) was associated with worse results. The VLBW children cognitive performance in the age of eight years benefits from more educated mothers, better prenatal care, and the baby gender as female.
Doutora em Ciências pela Fundação Oswaldo Cruz (FIOCRUZ). Médica Pediatra coordenadora do Núcleo de Atenção Interdisciplinar ao Recém-nascido de Risco da Maternidade Leila Diniz-Hospital Municipal Lourenço Jorge, Rio de Janeiro RJ, Brazil.
Maura Calixto Cecherelli de
MC
Rodrigues
Rosane Reis de
RR
Mello
Kátia Silveira da
KS
Silva
Márcia Lazaro de
ML
Carvalho
D002648:Child; D002657:Child Development / Q000502:physiology*; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000523:psychology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000254:growth & development*; D019102:Infant, Very Low Birth Weight / Q000254:growth & development*; D007360:Intelligence / Q000502:physiology*; D016015:Logistic Models; D008297:Male; D015999:Multivariate Analysis; D011446:Prospective Studies; D012307:Risk Factors; D012959:Socioeconomic Factors; D014888:Wechsler Scales