Distribution of lymphoid neoplasms in China: analysis of 4,638 cases according to the World Health Organization classification.
To estimate the distribution of lymphoid neoplasms in China, we conducted a comprehensive analysis, based on subtype, age, sex, and lesion, of primary and resected biopsy specimens of 4,638 lymphoid neoplasms diagnosed from 2004 to 2008 at 5 large hospitals. Of the 4,638 patients, mature B-cell neoplasms accounted for 64.3% of all lymphoid neoplasms, mature T/NK-cell neoplasms for 23.3%, and Hodgkin lymphoma for 8.6%. The most common subtype was diffuse large B-cell lymphoma (36.2%), followed by extranodal NK/T-cell lymphoma, nasal type (11.0%), classic Hodgkin lymphoma (8.4%), extranodal marginal zone B-cell lymphoma (7.7%), plasmacytic neoplasm (5.0%), and peripheral T-cell lymphoma, not otherwise specified (3.9%). For most lymphoid neoplasm subtypes, male subjects showed higher rates than female subjects. In summary, our study showed that the epidemiologic features of lymphoid neoplasms in China are distinct from those in Western countries and similar in many ways to those in other countries of the Far East.
Department of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 1 Shuai Fu Yuan Hu Tong, Beijing 100730, China.
Jian
J
Sun
Qunpei
Q
Yang
Zhaohui
Z
Lu
Miaoxia
M
He
Li
L
Gao
Minghua
M
Zhu
Lu
L
Sun
Lixin
L
Wei
Min
M
Li
Cuiling
C
Liu
Jie
J
Zheng
Weiping
W
Liu
Gandi
G
Li
Jie
J
Chen
D000293:Adolescent; D000328:Adult; D000368:Aged; D001402:B-Lymphocytes / Q000473:pathology; D002648:Child; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000145:classification* / Q000453:epidemiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012737:Sex Factors; D014944:World Health Organization