An incidental finding of cerebral meningioma on 99mTc-TRODAT-1 dopamine transporter SPECT/CT.
A 58-year-old woman presented with shuffling gait with small steps for 3 months. Tc-TRODAT-1 dopamine transporter SPECT/CT was prescribed to detect the function of the nigrostriatal system. It disclosed absence of uptake in the left putamen and diffusely decreased uptake in the right striatum. An unexpected mass with uneven uptake over the right frontal lobe was also noted. MRI demonstrated a large dura-related tumor, which was later proved as a meningioma after surgical intervention. Meningioma is the most common cause of tumor-induced parkinsonism. This case points to the significance of functional and structural fused neuroimaging in the evaluation of parkinsonism.
Department of Nuclear Medicine, Kaohsiung Veterans General Hospital, No 386, Dazhong 1st Rd, Zuoying District, Kaohsiung City 81362, Taiwan, ROC.
Yu-Li
YL
Chiu
Chin
C
Hu
Jie-Yuan
JY
Li
Mei-Jui
MJ
Weng
Wen-Chun
WC
Lin
Nan-Jing
NJ
Peng
D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D050483:Dopamine Plasma Membrane Transport Proteins / Q000378:metabolism*; D005260:Female; D006801:Humans; D033162:Incidental Findings; D008579:Meningioma / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology; D008875:Middle Aged; D064847:Multimodal Imaging; D015609:Organotechnetium Compounds; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D014326:Tropanes
D050483:Dopamine Plasma Membrane Transport Proteins; D015609:Organotechnetium Compounds; D014326:Tropanes; C104196:technetium Tc 99m TRODAT-1