A new sesquiterpene from an endophytic Aspergillus versicolor strain.
A new sesquiterpene, albican-1,14-diol (1), and seven known compounds, including sterigmatocystin (2), 3-hydroxy-5-(hydroxymethyl)-4-(4'-hydroxyphenoxy) pyrrolidin-2-one (3), (1H-indol-3-yl) oxoacetamide (4), indole-3-carboxylic acid (5), indole-3-acetic acid (6), indole-3-carboxaldehyde (7), and volemolide (8), were isolated from the cultures of Aspergillus versicolor, an endophytic fungus isolated from the marine green alga Codium fragile. The structure of 1 was elucidated by 1D, 2D NMR and mass spectroscopic techniques. The bioassay results showed that 1 possessed potent activity against brine shrimp, Escherichia coli, and Staphyloccocus aureus.
Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China.
Xiang-Hong
XH
Liu
Feng-Ping
FP
Miao
Xiao-Dong
XD
Li
Xiu-Li
XL
Yin
Nai-Yun
NY
Ji
D000818:Animals; D001156:Artemia / Q000187:drug effects; D001230:Aspergillus / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry* / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects
D012717:Sesquiterpenes