[Central autonomic failures].
Autonomic nervous system (ANS) modulates the function of all body organs through both parasympathetic and sympathetic fibers. Orthostatic hypotension is frequently observed in the course of central nervous system diseases including cortical (stroke, epilepsy, dementias), neurodegenerative (Parkinson's disease, multisystem atrophies) and spinal cord diseases. In some cases, the mechanism of orthostatic hypotension associated with central nervous system diseases involves a dysfunction of peripheral ANS fibers.
Université de Toulouse, CHU de Toulouse, service de pharmacologie clinique, Inserm U1048, 31000 Toulouse, France. jean-michel.senard@univ-tlse3.fr
Jean-Michel
JM
Senard
Fabien
F
Despas
Atul
A
Pathak
D001341:Autonomic Nervous System / Q000503:physiopathology; D001342:Autonomic Nervous System Diseases / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D007024:Hypotension, Orthostatic / Q000209:etiology*; D020961:Lewy Body Disease / Q000150:complications; D019578:Multiple System Atrophy / Q000150:complications / Q000175:diagnosis; D010300:Parkinson Disease / Q000209:etiology / Q000503:physiopathology; D054969:Primary Dysautonomias / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D013118:Spinal Cord Diseases / Q000150:complications