Diagnostic and prognostic significance of serum microRNAs in colorectal cancer.
MicroRNAs are short non-coding RNA molecules involved in the regulation of gene expression. There are few studies related to the determination of serum microRNAs in colorectal cancer. The identification of microRNAs in peripheral blood as noninvasive markers of tumor disease may lead to potential applications, although further clinical studies focusing on serum microRNAs are required to determine their clinical significance for the diagnosis and prognosis outcome of colorectal cancer.
Hospital Gutierrez Ortega, Valdepeñas, Ciudad Real, Spain. pablomensan@hotmail.com
Pablo
P
Menéndez
Pedro
P
Villarejo
David
D
Padilla
José M
JM
Menéndez
Jose A Rodríguez
JA
Montes
D014408:Biomarkers, Tumor / Q000097:blood*; D015179:Colorectal Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000235:genetics / Q000401:mortality; D005819:Genetic Markers; D006801:Humans; D035683:MicroRNAs / Q000097:blood*; D011379:Prognosis
D014408:Biomarkers, Tumor; D005819:Genetic Markers; D035683:MicroRNAs