Post-transplant plasmablastic lymphoma of the skin.
Plasmablastic lymphoma (PBL) is a recently described rare variant of diffuse large B-cell lymphoma characterised by its aggressive nature and plasmacytic differentiation. It most frequently arises in the oral cavity of human immunodeficiency virus (HIV)-infected patients. However extra-oral involvement is becoming increasingly recognised, particularly in HIV-negative patients. We report a case of PBL presenting as multiple violaceous nodules and plaques on the leg of a HIV-negative patient, 13-years post-renal transplant. To date, 20 cases of PBL presenting in the skin have been reported. We review and compare the clinico-pathological features of these cases.
Department of Dermatology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Catherine L
CL
Black
Erwin
E
Foster-Smith
Ian D
ID
Lewis
Randall J
RJ
Faull
Shireen K
SK
Sidhu
D017809:Fatal Outcome; D018023:HIV Seronegativity; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects; D016030:Kidney Transplantation / Q000009:adverse effects; D016403:Lymphoma, Large B-Cell, Diffuse / Q000209:etiology* / Q000276:immunology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010950:Plasma Cells / Q000473:pathology; D012878:Skin Neoplasms / Q000209:etiology* / Q000276:immunology / Q000473:pathology*; D013997:Time Factors
D007166:Immunosuppressive Agents