Pulmonary coccidiomycosis in New Delhi, India.
Coccidioidomycosis is an endemic disease of the western hemisphere. In cases occurring in non-endemic areas, eliciting a history of exposure as well as a high index of suspicion is imperative for timely and accurate diagnosis. In this case, a 65-year-old male presented to our hospital with fever, dry cough and malaise, and on X-ray chest, was found to have a lower lobe consolidation left lung with nodular lesions in both lungs and necrotic mediastinal lymphadenopathy. He lived in Arizona, USA, for 6 months before admission. Pulmonary coccidioidomycosis was confirmed by the isolation of Coccidioides spp. in pure culture from both broncho-alveolar lavage and lung biopsy specimens. The identity of the isolate was confirmed as C. posadasii by gene sequencing. The patient improved after being treated with fluconazole.
Department of Clinical Microbiology and Immunology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, India.
J K
JK
Oberoi
C
C
Wattal
P K
PK
Aggarwal
S
S
Khanna
A K
AK
Basu
K
K
Verma
D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D003045:Coccidioides / Q000302:isolation & purification*; D003047:Coccidioidomycosis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000382:microbiology; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D007194:India; D008172:Lung Diseases, Fungal / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
D000935:Antifungal Agents; D015725:Fluconazole