Periampullary diverticulum may be an important factor for the occurrence and recurrence of bile duct stones.
BACKGROUND
The aim of this study was to examine the relation between periampullary diverticula (PAD) and biliary tract stones.


METHODS
A total of 732 cases of patients with PAD identified from among 6,221 patients who underwent endoscopic retrograde cholangiopancreatography were compared to 750 controls (without PAD) in terms of biliary stone formation, incidence of sphincter of Oddi dysfunction (SOD), and choledocholithiasis. The biliary tract diseases were diagnosed based on medical history, clinical symptoms and signs, and imaging findings using ultrasonography, computed tomography, or magnetic resonance cholangiopancreatography.


RESULTS
The PAD group contained a significantly larger number of patients with biliary stones including stones in the primary common bile duct, SOD with bile duct stones (p < 0.05), and choledocholithiasis after cholecystectomy (p < 0.01).


CONCLUSIONS
There is a close correlation between PAD and the formation of biliary tract stones. A particularly close correlation was found between PAD and choledocholithiasis after cholecystectomy. PAD may be an important risk factor for the occurrence or recurrence of biliary tract stones.
Department of General Surgery, The First Hospital of Lanzhou University, Lanzhou, 730000 Gansu, China. lxdr21@sohu.com
Xun
X
Li
Kexiang
K
Zhu
Lei
L
Zhang
Wenbo
W
Meng
Wence
W
Zhou
Xiangliang
X
Zhu
Bo
B
Li
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014670:Ampulla of Vater; D002769:Cholelithiasis / Q000453:epidemiology* / Q000209:etiology*; D003137:Common Bile Duct Diseases / Q000150:complications*; D004240:Diverticulum / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence