Seasonal variation in the occurrence of venous thromboembolism: a report from the Korean Venous Thromboembolism Working Party.
There have been conflicting results on seasonal variation in the occurrence of venous thromboembolism (VTE). It also has never been studied in Asian population. To address these issues, we investigated seasonal changes of the incidence of VTE in Korean population using 1,495 patients with VTE between January 2001 and December 2010. VTE occurred most frequently in the winter and least frequently in the summer (χ2=11.83, P=0.008). In the subset analyses, the same trend was shown in the PE±DVT group, the unprovoked VTE group, and the VTE without malignancy group. The monthly occurrence rate peaked in December and was at its lowest in July (P=0.004). In conclusion, our study provides evidence that there is an increased risk for VTE in Korean population in the winter season.
Department of Internal Medicine, School of Medicine, CHA University, Korea.
Moon Ju
MJ
Jang
Hee-Jin
HJ
Kim
Soo-Mee
SM
Bang
Jeong-Ok
JO
Lee
Ho-Young
HY
Yhim
Yeo-Kyeoung
YK
Kim
Yang-Ki
YK
Kim
Won-Il
WI
Choi
Eun-Young
EY
Lee
In-Ho
IH
Kim
Seonyang
S
Park
Hee-Jung
HJ
Sohn
Duk-Kyung
DK
Kim
Minji
M
Kim
Doyeun
D
Oh
D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D012621:Seasons; D014680:Veins / Q000473:pathology*; D054556:Venous Thromboembolism / Q000175:diagnosis* / Q000453:epidemiology* / Q000473:pathology