Parallel microflow photochemistry: process optimization, scale-up, and library synthesis.
A novel, multimicrocapillary flow reactor (MμCFR) was constructed and applied to a series of sensitized photoadditions involving 2(5H)-furanones. The reactor allowed for rapid and energy-, time-, and space-efficient sensitizer screening, process optimization, validation, scale-up, and library synthesis.
Dublin City University, School of Chemical Sciences, Dublin 9, Ireland.
Alexander
A
Yavorskyy
Oksana
O
Shvydkiv
Norbert
N
Hoffmann
Kieran
K
Nolan
Michael
M
Oelgemöller
D020650:Combinatorial Chemistry Techniques; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D055668:Photochemical Processes
D005663:Furans