Body composition in older community-dwelling adults with hip fracture: portable field methods validated by dual-energy X-ray absorptiometry.
Ageing is associated with weight loss and subsequently poor health outcomes. The present study assessed agreement between two field methods, bioelectrical impedance spectroscopy (BIS) and corrected arm muscle area (CAMA) for assessment of body composition against dual-energy X-ray absorptiometry (DXA), the reference technique. Agreement between two predictive equations estimating skeletal muscle mass (SMM) from BIS against SMM from DXA was also determined. Assessments occurred at baseline < 14 d post-surgery (n 79), and at 6 months (6M; n 75) and 12 months (12M; n 63) in community-living older adults after surgical treatment for hip fracture. The 95 % limits of agreement (LOA) between BIS and DXA, CAMA and DXA and the equations and DXA were assessed using Bland-Altman analyses. Mean bias and LOA for fat-free mass (FFM) between BIS and DXA were: baseline, 0.7 (-10.9, 12.4) kg; 6M, - 0.5 (-20.7, 19.8) kg; 12M, 0.1 (-8.7, 8.9) kg and for SMM between CAMA and DXA were: baseline, 0.3 (-11.7, 12.3) kg; 6M, 1.3 (-4.5, 7.1) kg; 12M, 0.9 (-5.4, 7.2) kg. Equivalent data for predictive equations against DXA were: equation 1: baseline, 15.1 (-9.5, 20.6) kg; 6M, 17.1 (-12.0, 22.2) kg; 12M, 17.5 (-13.0, 22.0) kg; equation 2: baseline, 12.6 (-7.3, 19.9) kg; 6M, 14.4 (-9.7, 19.1) kg; 12M, 14.8 (-10.7, 18.9) kg. Proportional bias (BIS: β = -0.337, P< 0.001; CAMA: β = -0.294, P< 0.001) was present at baseline but not at 6M or 12 M. Clinicians should be cautious in using these field methods to predict FFM and SMM, particularly in the acute care setting. New predictive equations would be beneficial.
Department of Nutrition and Dietetics, School of Medicine, Flinders University, GPO Box 2100, Adelaide, South Australia 5001, Australia.
Anthony M
AM
Villani
Michelle
M
Miller
Ian D
ID
Cameron
Susan
S
Kurrle
Craig
C
Whitehead
Maria
M
Crotty
D015502:Absorptiometry, Photon; D000359:Aftercare; D000368:Aged; D000369:Aged, 80 and over; D000886:Anthropometry / Q000379:methods*; D001132:Arm; D001823:Body Composition; D003430:Cross-Sectional Studies; D058266:Dielectric Spectroscopy; D005260:Female; D005592:Fracture Fixation; D006620:Hip Fractures / Q000150:complications / Q000534:rehabilitation* / Q000601:surgery; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging / Q000473:pathology*; D055948:Sarcopenia / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D012720:Severity of Illness Index; D012885:Skinfold Thickness; D013021:South Australia; D013223:Statistics as Topic