Usefulness of the DL in ME with NBI for determining the expanded area of early-stage differentiated gastric carcinoma.
OBJECTIVE
To investigate whether magnifying endoscopy with narrow band imaging (ME-NBI) is useful for evaluating the area of superficial, depressed- or flat-type differentiated adenocarcinoma of the stomach.


METHODS
This procedure was performed in Saitama Medical University International Medical Center, Japanese Red Cross Kumamoto Hospital and Kitakyushu Municipal Medical Center. The subjects were 31 patients in whom biopsy findings, from superficial, depressed- or flat-type gastric lesion, suggested differentiated adenocarcinoma in the above 3 hospitals between January and December 2009. Biopsy was performed on the lesion and non-lesion sides of a boundary (imaginary boundary) visualized on ME-NBI. The results were pathologically investigated. We evaluated the accuracy of estimating a demarcation line (DL) on ME-NBI in comparison with biopsy findings as a gold standard.


RESULTS
The DL that could be recognized at 2 points on the orifice and anal sides of each lesion during ME-NBI was consistent with the pathological findings in 22 patients with 0-IIc lesions, 7 with 0-IIb lesions, and 2 with 0-IIb + IIc lesions, showing an accuracy of 100%.


CONCLUSIONS
The results suggest the usefulness of ME-NBI for evaluating the area of superficial, depressed- and flat-type differentiated adenocarcinoma of the stomach.
Kouichi Nonaka, Yasutoshi Ochiai, Osamu Togawa, Masamitsu Nakao, Makoto Nishimura, Keiko Ishikawa, Shin Arai, Hiroto Kita, Department of Gastroenterology, Saitama Medical University International Medical Center, Saitama 350-1298, Japan.
Kouichi
K
Nonaka
Masaaki
M
Namoto
Hideki
H
Kitada
Michio
M
Shimizu
Yasutoshi
Y
Ochiai
Osamu
O
Togawa
Masamitsu
M
Nakao
Makoto
M
Nishimura
Keiko
K
Ishikawa
Shin
S
Arai
Hiroto
H
Kita