Congenital cystic adenomatoid malformation in adulthood complicated by Mycobacterium celatum infection.
A 25-year-old woman with no underlying disease presented with a large fluid-filled cavitary lesion in the right lung. Mycobacterium celatum was isolated from the cavitary fluid, and treatment with ethambutol, rifampicin, and clarithromycin was initiated. After 4 months of treatment, right lower pulmonary lobectomy was performed. Histological examination confirmed M. celatum infection as well as concurrent congenital cystic adenomatoid malformation (CCAM). M. celatum has been implicated in opportunistic infections. This infection, however, was related to underlying CCAM, which resulted in a large cavitary lesion. CCAM diagnosed in adulthood is rare, and is made more challenging by an infectious complication.
National Hospital Organization, Omuta National Hospital, Japan. ikegame-s@oomuta-h.com
Satoshi
S
Ikegame
Yoshinori
Y
Nagamatsu
Nobuhiko
N
Nagata
Yuko
Y
Kazumi
Satoshi
S
Mitarai
Yasunori
Y
Iwasaki
Chika
C
Harada
Hiroyuki
H
Kumazoe
Masayuki
M
Kawasaki
Akira
A
Kajiki
D000328:Adult; D001999:Bronchoscopy; D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000150:complications* / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008169:Lung Abscess / Q000150:complications / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications* / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D009170:Nontuberculous Mycobacteria / Q000187:drug effects; D011013:Pneumonectomy; D014057:Tomography, X-Ray Computed