Bilateral vagus nerve neurolymphomatosis diagnosed using PET/CT and diffusion-weighted MRI.
In neurolymphomatosis, malignant lymphocytes infiltrate the peripheral nervous system in the presence of a known or unknown hematological malignancy. This report describes the findings of diffusion-weighted MRI and F-FDG PET/CT in a 65-year-old man with hoarseness. Results revealed a mass with restricted diffusion on diffusion-weighted imaging in the right visceral vascular space, increased uptake of F-FDG, and other masses at distant peripheral nerves. Restaging PET/CT showed involvement of the right brachial plexus and right sciatic nerve. Biopsy and immunohistochemistry of the right vagus nerve and cervical lymphadenopathy revealed a diffuse large B-cell non-Hodgkin lymphoma.
Department of Radiology, Clínica Radiológica Luiz Felippe Mattoso, Rio de Janeiro, Brazil.
Boasquevisque
B
Gs
Guidoni
G
J
Moreira de Souza
Mde S
LA
Gonçalves
G
Pg
Andrade
A
Cv
Pedras
P
Fv
Boasquevisque
B
Em
Boasquevisque
B
Ets
D000368:Aged; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D064847:Multimodal Imaging; D009423:Nervous System Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D020421:Vagus Nerve Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology