Poly[2-(methacryloyloxy)ethylphosphorylcholine]-coated iron oxide nanoparticles: synthesis, colloidal stability and evaluation for stem cell labelling.
Poly[2-(methacryloyloxy)ethylphosphorylcholine]-coated SPIONs were prepared through ATRP and amidation coupling reactions. The coated SPIONs exhibited high stability and re-dispersability in phosphate buffered saline and uptake in a stem cell line, with high T(2) relaxivity.
Department of Chemistry, University of Liverpool, Liverpool, UK.
Anita K
AK
Peacock
Solène I
SI
Cauët
Arthur
A
Taylor
Patricia
P
Murray
Steve R
SR
Williams
Jonathan V M
JV
Weaver
Dave J
DJ
Adams
Matthew J
MJ
Rosseinsky
D000818:Animals; D002021:Buffers; D060326:Chemistry Techniques, Synthetic; D003102:Colloids; D004355:Drug Stability; D005290:Ferric Compounds / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism*; D008689:Methacrylates / Q000737:chemistry*; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry*; D010767:Phosphorylcholine / Q000031:analogs & derivatives* / Q000737:chemistry; D011109:Polymethacrylic Acids; D013194:Staining and Labeling; D013234:Stem Cells / Q000378:metabolism*
D002021:Buffers; D003102:Colloids; D005290:Ferric Compounds; D008689:Methacrylates; D011109:Polymethacrylic Acids; C115766:poly(2-methacryloyloxyethyl-phosphorylcholine); D010767:Phosphorylcholine; C000499:ferric oxide