Silver/Polyethylene oxide nanocomposite: UV-fabrication, characterization, and antibacterial activity.
In this article, silver-polyethylene oxide (Ag/PEO) biocompatible nanocomposite (BCNC) were successfully green synthesized by mixture containing low MW PEO, silver nitrate and by UV-irradiation at room temperature. The initially broad and asymmetric surface plasmon resonance (SPR) band was narrowed and blue-shifted as the exposure time to UV light was increased. Samples illuminated up to 3 h have an average particle size near 12.0 nm; a decrease to 10.0 nm was observed for longer exposure times up to 24 h. The asymmetric SPR band was due to particle aggregation; higher irradiation times led to a uniform particle distribution within the polymer matrix. The synthesized colloids and thin films have potent antibacterial activity toward gram-negative bacterium Escherichia coil (E. coli), and this activity is completely strong. The concentration of silver leading to a complete inhibition of bacteria growth was revealed as low as at 0.50 microg x ml(-1) and found much lower compared to other reports. Thus Ag/PEO BCNC could be suitable to antimicrobial applications and medical devices.
Department of Material Science and Engineering, Najafabad Branch, Islamic Azad University, Najafabad 85141-43131, Iran.
Ali
A
Sharifian-Esfahani
Mohammad Taghi
MT
Salehi
Mojtaba
M
Nasr-Esfahani
Ehsan
E
Ekramian
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D004926:Escherichia coli / Q000166:cytology* / Q000187:drug effects*; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry* / Q000648:ultrastructure; D011092:Polyethylene Glycols / Q000737:chemistry*; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology*; D014466:Ultraviolet Rays
D000900:Anti-Bacterial Agents; D012834:Silver; D011092:Polyethylene Glycols