Successful treatment of a large primary cardiac lymphoma by surgical resection combined with chemotherapy: report of a case.
Primary cardiac lymphoma (PCL) is a rare tumor for which no treatment strategy has yet been established. This report presents the case of a large PCL that was successfully treated by emergency surgical resection combined with postoperative chemotherapy. A 60-year-old male was referred because of dyspnea on effort. Echocardiography and computed tomography scans revealed a 10 cm tumor in the right ventricle and right atrium. The tumor was suspected to be malignant because positron emission tomography/computed tomography showed a high uptake at the tumor site. The tumor was large enough to cause life-threatening obstruction, and cardiologists were therefore reluctant to perform a percutaneous biopsy. The patient underwent emergency resection. The postoperative course was satisfactory, and the diagnosis of diffuse large B cell lymphoma (DLBCL) was thus confirmed. The patient achieved complete remission after being treated with chemotherapy for DLBCL. He was alive 1 year after surgery, without any signs of recurrence.
Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan. t-kawamura@surg1.med.osaka-u.ac.jp
Takuji
T
Kawamura
Taichi
T
Sakaguchi
Hiroyuki
H
Nishi
Shigeru
S
Miyagawa
Yasushi
Y
Yoshikawa
Takashi
T
Yamauchi
Satsuki
S
Fukushima
Shunsuke
S
Saito
Yoshiki
Y
Sawa
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D006348:Cardiac Surgical Procedures; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D004452:Echocardiography; D004630:Emergencies; D006338:Heart Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011239:Prednisolone / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone