[Significance of frozen section diagnosis for the management of laryngeal tumors].
The frozen section procedure for immediate intraoperative pathological diagnosis represents a pivotal method in tumor diagnosis. In laryngeal tumors the most frequent indication for the use of this method is the documentation of the residual tumor status, while intraoperative consultation with the purpose of primary tumor diagnosis is less common. The specimen management employed in each case should be chosen depending on the clinical question: while the collection of a maximum amount of tissue is advisable for the determination of the residual tumor status, sparing a portion of the remaining tissue for possible future examinations is advisable in the case of primary tumor diagnosis. Moreover, intraoperative frozen section diagnosis with no immediate consequences should be avoided.
Institut für Pathologie, Justus-Liebig-Universität Gießen, Langhansstr. 10, 35392, Gießen, Deutschland. th.dreyer@gmx.de
T
T
Dreyer
B
B
Etschmann
T
T
Kroll
A
A
Bräuninger
S
S
Gattenlöhner
A
A
Benz
D000465:Algorithms; D014408:Biomarkers, Tumor / Q000032:analysis; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery; D003299:Cooperative Behavior; D003661:Decision Support Techniques; D003937:Diagnosis, Differential; D005629:Frozen Sections; D006801:Humans; D033183:Interdisciplinary Communication; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery*; D007830:Larynx / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology; D018365:Neoplasm, Residual / Q000473:pathology / Q000601:surgery*; D009378:Neoplasms, Multiple Primary / Q000473:pathology / Q000601:surgery; D009382:Neoplasms, Unknown Primary / Q000473:pathology / Q000601:surgery; D011237:Predictive Value of Tests; D012086:Reoperation; D021701:Sentinel Lymph Node Biopsy
D014408:Biomarkers, Tumor