Interleukin-36 cytokines enhance the production of host defense peptides psoriasin and LL-37 by human keratinocytes through activation of MAPKs and NF-κB.
Toan The
TT
Nguyen
François
F
Niyonsaba
Hiroko
H
Ushio
Toshihiro
T
Akiyama
Chanisa
C
Kiatsurayanon
Rithee
R
Smithrithee
Shigaku
S
Ikeda
Ko
K
Okumura
Hideoki
H
Ogawa
D023181:Antimicrobial Cationic Peptides / Q000235:genetics / Q000378:metabolism*; D002478:Cells, Cultured; D004789:Enzyme Activation; D006801:Humans; D007375:Interleukin-1 / Q000378:metabolism*; D015603:Keratinocytes / Q000187:drug effects / Q000201:enzymology / Q000276:immunology / Q000378:metabolism*; D020928:Mitogen-Activated Protein Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D016328:NF-kappa B / Q000378:metabolism*; D010766:Phosphorylation; D047428:Protein Kinase Inhibitors / Q000494:pharmacology; D000075023:S100 Calcium Binding Protein A7; D009418:S100 Proteins / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D013997:Time Factors; D015854:Up-Regulation; D054804:Cathelicidins
D023181:Antimicrobial Cationic Peptides; D007375:Interleukin-1; D016328:NF-kappa B; D047428:Protein Kinase Inhibitors; D000075023:S100 Calcium Binding Protein A7; D009418:S100 Proteins; C089242:S100A7 protein, human; D020928:Mitogen-Activated Protein Kinases; D054804:Cathelicidins