[Drug induced man infertility].
Infertility is defined as the inability to conceive in a given pair, despite regular sexual intercourse for at least 12 months. In 2004, the World Health Organization has recognized infertility as a social disease. Nowadays, the problem of infertility, meets 1 to 6 pairs, which affects approximately 13-15% of couples the world's population. In Poland, this problem affects between 700 thousand to a million pairs. Male infertility may arise from the use of pharmacotherapy and adverse drug reactions. This publication provides an overview of the type of drugs impairing function of male genitalia and to discuss mechanisms for their action on the process of spermatogenesis.
Katedra Patofizjologii, Uniwersytet Jagielloński Collegium Medicum, Kraków. bskowron@cm-uj.krakow.pl
Beata
B
Skowron
Kajetan
K
Juszczak
Piotr J
PJ
Thor
D000959:Antihypertensive Agents / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000009:adverse effects; D064420:Drug-Related Side Effects and Adverse Reactions; D005837:Genitalia, Male / Q000187:drug effects; D006801:Humans; D007248:Infertility, Male / Q000139:chemically induced*; D008297:Male; D004364:Pharmaceutical Preparations / Q000145:classification; D013091:Spermatogenesis / Q000187:drug effects
D000959:Antihypertensive Agents; D000970:Antineoplastic Agents; D004364:Pharmaceutical Preparations