Xylitol carryover effects on salivary mutans streptococci after 13 months of chewing xylitol gum.
To assess mutans streptococci (MS) during xylitol gum chewing (mean 3.8 g/day, 2.9 times/day) for 13 months and then for 15 months after the intervention, Japanese mothers with high salivary MS were randomized into two groups: xylitol gum (n = 56) and no gum (n = 51). The proportion of low MS levels was highest at 3 months of consumption (48.8%), but was significantly lower compared to baseline at the end of the intervention (p < 0.001). MS levels did not change during the postintervention period. The data suggest that in the xylitol group 23.3% showed persistent carryover effects by xylitol gum chewing in the postintervention period.
Pediatric Dental Clinic, Okayama University Hospital, Okayama, Japan.
C
C
Shinga-Ishihara
Y
Y
Nakai
P
P
Milgrom
E
E
Söderling
M
M
Tolvanen
K
K
Murakami
D001422:Bacterial Adhesion; D002327:Cariostatic Agents / Q000494:pharmacology*; D002638:Chewing Gum; D016009:Chi-Square Distribution; D003773:Dental Plaque / Q000382:microbiology; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D009035:Mothers; D012463:Saliva / Q000382:microbiology*; D018709:Statistics, Nonparametric; D013295:Streptococcus mutans / Q000187:drug effects* / Q000502:physiology; D013549:Sweetening Agents / Q000494:pharmacology; D014993:Xylitol / Q000494:pharmacology*
D002327:Cariostatic Agents; D002638:Chewing Gum; D013549:Sweetening Agents; D014993:Xylitol