Diastereoselective synthesis of half-sandwich chiral-at-metal cobaltacycles by oxidative cyclisation.
Reaction of chiral ester linked diynes with chlorotris(triphenylphosphine)cobalt(I) and sodium cyclopentadienide gave (η(5)-cyclopentadienyl)(triphenylphosphine) cobaltacyclopentadiene complexes as single chiral-at-metal diastereoisomers, including a non-racemic example synthesised in three steps from (S)-3-butyn-2-ol.
School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK.
Jahangir
J
Amin
Christopher J
CJ
Richards
D003035:Cobalt / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003500:Cyclization; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D013237:Stereoisomerism
D009942:Organometallic Compounds; D003035:Cobalt