Stem cell transplantation in cardiovascular disease: an update.
Despite the development of novel therapeutic strategies, cardiovascular diseases remain the main cause of morbidity and mortality worldwide. Many phase 1 and 2 clinical trials have reported the safety, feasibility and promising potential of stem cell transplantation, however, the optimal  cell types, timing of infusion, cell dosage and routes of administration remain to be determined. This paper reviews the findings of various clinical studies and discusses the challenges facing the delivery of stem cell therapy in cardiovascular diseases.
Institute of Burn Research, Southwest Hospital, Third Military Medical University, Chongqing, China.
M
M
Teng
Z
Z
Geng
L
L
Huang
X
X
Zhao
D002318:Cardiovascular Diseases / Q000601:surgery*; D002986:Clinical Trials as Topic; D005240:Feasibility Studies; D006801:Humans; D033581:Stem Cell Transplantation / Q000009:adverse effects