[Dynamic pathologic changes in pigs infected with Taenia solium].
Four three-way crossed hybrid pigs were infected each with 80,000 Taenia solium eggs. One pig was sacrificed respectively at 40, 80, 120, and 150 d post-infection, and tissue samples containing cysticerci were collected for pathological sections. The results showed that in 40-80 days, cysticerci in the liver were surrounded by membrane formed with the hyperplastic fibrous connective tissue and inflammatory cells. On 120th day, a large number of the cysticerci were dead or calcified. On 150th day, all cysticerci died or calcified. On 40th, day, the inflammatory cells infiltrated around the cysticerci in the tongue and skeletal muscle, and the inflammatory responses near the scolex were more serious than that near cyst wall. In the 80-150 days, the inflammatory cells showed band like distribution. The pathological response in cardiac muscle was similar to that of the skeletal muscle and the tongue, but with more inflammatory cells. On 40th day, there were a few inflammatory cells infiltrating around cysticerci in the brain, in the 80-150 days, a large number of inflammatory cells aggregated around the cysticerci. The inflammatory response in the tissues progressed with the duration of infection and the inflammation in the liver was significantly stronger than that in other tissues.
Department of Clinical Laboratory Sciences, Guiyang Medical College, Guiyang 550004, China.
Wen
W
Fang
Liang-liang
LL
Xiao
Huai-en
HE
Bao
Rong
R
Mu
D000818:Animals; D001921:Brain / Q000469:parasitology / Q000473:pathology; D003551:Cysticercosis / Q000473:pathology*; D008099:Liver / Q000469:parasitology / Q000473:pathology; D018482:Muscle, Skeletal / Q000469:parasitology / Q000473:pathology; D013552:Swine; D013553:Swine Diseases / Q000469:parasitology* / Q000473:pathology; D041201:Taenia solium