Cyclometallation of arylimines and nitrogen-containing heterocycles via room-temperature C-H bond activation with arene ruthenium(II) acetate complexes.
The reaction of [RuCl(2)(p-cymene)](2) with arylimines and 4 equiv. of KOAc in methanol at room temperature produces stable (N^C)-cyclometallated ruthenium(II) complexes via C-H bond activation/deprotonation. This method can be applied also to nitrogen-containing molecules: N-phenylpyrazole, 2-phenyl-2-oxazoline and benzo[h]quinoline. N-Phenyl-pyrazole, [RuCl(2)(p-cymene)](2) and diphenylacetylene directly lead to alkyne insertion into the metallacycle C-Ru bond.
Institut des Sciences Chimiques de Rennes, UMR 6226 CNRS-Université de Rennes 1, Centre of Catalysis and Green Chemistry, Rennes, France.
Bin
B
Li
Thierry
T
Roisnel
Christophe
C
Darcel
Pierre H
PH
Dixneuf