Widespread intracranial calcification, seizures and extrapyramidal manifestations in a case of hypoparathyroidism.
Hypoparathyroidism can present with neurological complaints like seizures, parasthesias, depression, psychosis, extrapyramidal manifestations and features of raised intracranial pressure. Hypoparathyroidism and pseudohypoparathyroidism are the most common causes of pathological basal ganglia calcification. A 50 year male presented with generalized seizures and extrapyramidal features like tremors and rigidity. Investigations revealed that he had hypocalcemia, hyperphosphatemia and very low PTH levels, CT scan of head showed calcification of bilateral basal ganglia, cerebellum and subcortical white matter of frontal and parietal lobes. He showed remarkable recovery on restoration of normal serum calcium levels. Hypoparathyroidism should be kept in the differential diagnosis of patients presenting with seizures and extrapyramidal features.
Department of Medicine, Jawaharlal Nehru Medical College, Aligarh, India.
Imran
I
Rizvi
Noor Alam
NA
Ansari
Mujahid
M
Beg
Md Dilawez
MD
Shamim