Anticoccidial activity of traditional Chinese herbal Dichroa febrifuga Lour. extract against Eimeria tenella infection in chickens.
The study was conducted on broiler birds to evaluate the anticoccidial efficacy of an extract of Chinese traditional herb Dichroa febrifuga Lour. One hundred broiler birds were assigned to five equal groups. All birds in groups 1-4 were orally infected with 1.5 × 10(4) Eimeira tenella sporulated oocysts and birds in groups 1, 2 and 3 were medicated with 20, 40 mg extract/kg feed and 2 mg diclazuril/kg feed, respectively. The bloody diarrhea, oocyst counts, intestinal lesion scores, and the body weight were recorded to evaluate the anticoccidial efficacy. The results showed that D. febrifuga extract was effective against Eimeria infection; especially 20 mg D. febrifuga extract/kg feed can significantly increase body weight gains and reduce bloody diarrhea, lesion score, and oocyst excretion in comparison to infected-unmedicated control group.
Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, People's Republic of China.
De-Fu
DF
Zhang
Bing-Bing
BB
Sun
Ying-Ying
YY
Yue
Qian-Jin
QJ
Zhou
Ai-Fang
AF
Du
D000818:Animals; D000981:Antiprotozoal Agents / Q000008:administration & dosage* / Q000302:isolation & purification; D001835:Body Weight; D002645:Chickens; D002681:China; D003048:Coccidiosis / Q000188:drug therapy / Q000469:parasitology / Q000473:pathology / Q000662:veterinary*; D003967:Diarrhea / Q000188:drug therapy / Q000469:parasitology / Q000473:pathology / Q000662:veterinary; D016786:Eimeria tenella / Q000187:drug effects* / Q000302:isolation & purification; D029001:Herbal Medicine; D029628:Hydrangeaceae / Q000737:chemistry*; D033661:Oocysts / Q000187:drug effects; D010936:Plant Extracts / Q000008:administration & dosage* / Q000302:isolation & purification; D011201:Poultry Diseases / Q000188:drug therapy* / Q000469:parasitology / Q000473:pathology
D000981:Antiprotozoal Agents; D010936:Plant Extracts