Prevalence of primary aldosteronism in hypertensive subjects with hyperglycemia.
The aim of this study was to examine the prevalence of primary aldosteronism (PA) in hypertensive patients with hyperglycemia. Two hundred and thirty-two hypertensive patients with hyperglycemia were screened for PA. Fifty-four subjects with an aldosterone/rennin activity ratio >20 ng/dL per ng/mL/hour underwent a saline loading test. Primary aldosteronism was present in 22.4% of patients with a plasma aldosterone concentration >5 ng/dL and 11.6% of those with plasma aldosterone concentrations >10 ng/dL. There were 14.0%-23.0% patients with PA in the diabetes mellitus group, 2.3%-23.3% in the impaired glucose tolerance group, and 9.1% in the impaired fasting glucose group. Primary aldosteronism is common in hypertensive individuals with hyperglycemia.
Institute of Hypertension of the People's Hospital of Xinjiang Uygur Autonomous Region, Center of Diagnosis, Treatment and Research of Hypertension in Xinjiang, Xinjiang, China. lnanfang2009@yahoo.com.cn
Nanfang
N
Li
Menghui
M
Wang
Hongmei
H
Wang
Delian
D
Zhang
Xinling
X
Wang
Feiya
F
Zu
Guijuan
G
Chang
Keming
K
Zhou
D000328:Adult; D000368:Aged; D048909:Diabetes Complications; D005260:Female; D018149:Glucose Intolerance / Q000150:complications; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications* / Q000175:diagnosis; D006943:Hyperglycemia / Q000150:complications*; D006973:Hypertension / Q000150:complications*; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D011236:Prediabetic State / Q000150:complications