[A case of adult primitive neuroectodermal tumor(PNET)with multiple lung metastases effectively treated with ADM, IFM(AI)regimen].
The patient was a 48-year-old male with a right subclavicular tumor. The pathological diagnosis showed primitive neuroectodermal tumor(PNET)because of the rosette formation and the positive neurogenic marker.Radiation was administered at a total dose of 50 Gy, because surgical resection would induce the loss of right arm function. CT examination demonstrated a reduction of the primary tumor and new multiple lung metastases. The patient received intravenous AI regimen(ADM and IFM). After the 7th course, both the primary tumor and multiple lung metastases decreased. AI regimen might be effective for PNET.
Dept. of Surgery, Yamagata Prefectural Shinjo Hospital, Japan.
Tomoharu
T
Ishiyama
Akira
A
Jinguu
Hidekazu
H
Matsumoto
Jirou
J
Kikuchi
Tomonobu
T
Suzuki
Mitsunori
M
Yamakawa
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001707:Biopsy, Needle; D001897:Boronic Acids / Q000008:administration & dosage; D000069286:Bortezomib; D004317:Doxorubicin / Q000627:therapeutic use; D006258:Head and Neck Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D008558:Melphalan / Q000008:administration & dosage; D008875:Middle Aged; D008936:Mitolactol / Q000627:therapeutic use; D008937:Mitomycins / Q000627:therapeutic use; D018242:Neuroectodermal Tumors, Primitive / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D011719:Pyrazines / Q000008:administration & dosage; D016879:Salvage Therapy; D013405:Suicide; D014057:Tomography, X-Ray Computed
D001897:Boronic Acids; D008937:Mitomycins; D011719:Pyrazines; D000069286:Bortezomib; D004317:Doxorubicin; D008936:Mitolactol; D008558:Melphalan