Isolation and structure elucidation of tetrameric procyanidins from unripe apples (Malus pumila cv. Fuji) by NMR spectroscopy.
Procyanidins are plant secondary metabolites widely consumed and known to have various physiological functions, but their bioavailability and mechanism of action are still unclear especially for larger oligomers. One of the reasons is scarce information about the detailed structure of oligomeric procyanidins. As for apple, structures of procyanidin components larger than trimers are scarcely known. In this study, 11 tetrameric procyanidins including two known compounds were isolated from unripe apples (Malus pumila cv. Fuji) and identified by NMR spectroscopic analysis and phloroglucinol degradation. As a result, the detailed structural diversity of tetrameric procyanidins in apple was established.
Asahi Group Holdings, Ltd., 1-21, Midori 1, Moriya, Ibaraki 302-0106, Japan. syohei.nakashima@asahigroup-holdings.com
Shohei
S
Nakashima
Chihiro
C
Oda
Susumu
S
Masuda
Motoyuki
M
Tagashira
Tomomasa
T
Kanda
D009682:Magnetic Resonance Spectroscopy; D027845:Malus / Q000737:chemistry*; D015394:Molecular Structure; D044945:Proanthocyanidins / Q000737:chemistry* / Q000302:isolation & purification*
D044945:Proanthocyanidins