One-pot consecutive reactions based on the synthesis of conjugated enones by the re-catalysed Meyer-Schuster rearrangement.
Re catalysis in one-pot reactions: An atom-economical, one-pot strategy that involves alkyne deprotonation and a subsequent rhenium(V)-catalysed Meyer-Schuster rearrangement of the alkynol to provide α,ß-unsaturated enones in high yield has been developed (see scheme). Subsequent in situ hydride reduction or Diels-Alder reaction of the enones provided products in good-to-high overall yields.
Dipartimento di Chimica, Università di Pavia, Via Taramelli 12, 27100 Pavia, Italy.
Elio
E
Mattia
Alessio
A
Porta
Valentina
V
Merlini
Giuseppe
G
Zanoni
Giovanni
G
Vidari
D000447:Aldehydes / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D061565:Cycloaddition Reaction; D007536:Isomerism; D015394:Molecular Structure; D012211:Rhenium / Q000737:chemistry*
D000447:Aldehydes; D000475:Alkenes; D012211:Rhenium