Do basophile structures as age dependent phenomenon indicate small vessel wall damage?
Here we demonstrate basophile structures located in the arteriolar wall and being associated with a plasma-protein-leakage. We assume, that the structures indicate blood-brain-barrier-disturbances and degenerative small vessel wall alterations.
Department of Neurology, Otto-von-Guericke-University, Leipziger Strasse 44, 39120 Magdeburg, Germany. stefanie.schreiber@med.ovgu.de
Stefanie
S
Schreiber
Cornelia
C
Garz
Celine
C
Bueche
Doerthe
D
Kuester
Siegfried
S
Kropf
Sabine
S
Westphal
Berend
B
Isermann
Andreas
A
Oldag
Hans-Jochen
HJ
Heinze
Michael
M
Goertler
Klaus
K
Reymann
Holger
H
Braun
D000364:Agaricus / Q000378:metabolism; D000367:Age Factors; D000818:Animals; D001160:Arterioles / Q000378:metabolism; D001812:Blood-Brain Barrier; D001921:Brain / Q000378:metabolism; D039521:CD11c Antigen / Q000096:biosynthesis; D002196:Capillaries / Q000378:metabolism; D016207:Cytokines / Q000378:metabolism; D003713:Dendritic Cells / Q000166:cytology; D004730:Endothelium, Vascular / Q000378:metabolism*; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000378:metabolism; D007371:Interferon-gamma / Q000378:metabolism; D037181:Lectins, C-Type / Q000096:biosynthesis; D008297:Male; D051379:Mice; D008833:Microcirculation; D051381:Rats; D013154:Spleen / Q000166:cytology; D047071:beta-Glucans / Q000378:metabolism; D000099181:Dectin-1
D039521:CD11c Antigen; D016207:Cytokines; D016178:Granulocyte-Macrophage Colony-Stimulating Factor; D007371:Interferon-gamma; D037181:Lectins, C-Type; D047071:beta-Glucans; D000099181:Dectin-1