Evidence-based pediatric orthopaedics: an introduction, part 2.
Evidence-based medicine carefully assesses the information available in the literature by assessing both the results and the quality of the underlying studies. Studies are prone to both confounding and bias, and practitioners need to have a basic knowledge of how these factors are affected by various study types. This paper addresses the issues facing various study designs with the goal of helping practitioners understand what they can actually learn from different study designs.
The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
James G
JG
Wright
Mininder S
MS
Kocher
James O
JO
Sanders
D015982:Bias; D002648:Child; D015986:Confounding Factors, Epidemiologic; D019317:Evidence-Based Medicine; D006801:Humans; D019637:Orthopedic Procedures / Q000379:methods*; D009985:Orthopedics / Q000458:organization & administration*; D010372:Pediatrics / Q000458:organization & administration; D012107:Research Design