[A case of liver metastases of sigmoid colon cancer treated effectively by oral UFT/LV].
The patient was a 77-year-old woman with multiple liver metastases of sigmoid colon cancer. She underwent low anterior resection for sigmoid colon cancer. After surgery, she selected oral administration of UFT and LV for liver metastases and multiple lymph node metastases. After two courses, the liver metastases had markedly diminished. Thirty-two months later, liver metastases had disappeared on computer tomography. This therapy was continued for five years, and recurrences are no longer shown. Severe adverse effects were not observed. Oral anti-cancer drugs can serve as effective therapy for advanced colorectal cancer of old patients.
Dept. of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, Japan.
Daisuke
D
Yamamoto
Hiroyuki
H
Bando
Masashi
M
Matsunaga
Yasuhiro
Y
Ishiyama
Mami
M
Kaneko
Michihiro
M
Yamamoto
Masanori
M
Kotake
Noriyuki
N
Inaki
Masaru
M
Kurokawa
Tetsuji
T
Yamada
D000284:Administration, Oral; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage*; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D012811:Sigmoid Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005641:Tegafur / Q000008:administration & dosage / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014498:Uracil / Q000008:administration & dosage / Q000627:therapeutic use
D005641:Tegafur; D014498:Uracil; D002955:Leucovorin