Radioprotective property of polysaccharide in Tinospora cordifolia.
Radioprotective activity of a polysaccharide preparation from the Indian medicinal plant. Tinospora cordifolia Miers has been established using Saccharomyces cerevisiae X2180 strain as the in vivo test model. The entire activity could be attributed to the radical scavenging capacity of the preparation, as it did not enhance the expression of the protective enzymes, catalase and superoxide dismutase in the yeast cells.
Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai 400 085, India.
Mahesh
M
Subramanian
Gajanan J
GJ
Chintalwar
Subrata
S
Chattopadhyay
D002470:Cell Survival / Q000187:drug effects / Q000528:radiation effects; D004249:DNA Damage; D005685:Galactans / Q000737:chemistry; D018384:Oxidative Stress / Q000187:drug effects / Q000528:radiation effects; D011134:Polysaccharides / Q000737:chemistry / Q000494:pharmacology*; D011837:Radiation-Protective Agents / Q000737:chemistry / Q000494:pharmacology*; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000187:drug effects / Q000378:metabolism / Q000528:radiation effects; D031610:Tinospora / Q000737:chemistry*
D005685:Galactans; D011134:Polysaccharides; D011837:Radiation-Protective Agents; C005653:arabinogalactan