Acute bone marker responses to whole-body vibration and resistance exercise in young women.
Whole-body vibration (WBV) augments the musculoskeletal effects of resistance exercise (RE). However, its acute effects on bone turnover markers (BTM) have not been determined. This study examined BTM responses to acute high-intensity RE and high-intensity RE with WBV (WBV+RE) in young women (n=10) taking oral contraceptives in a randomized, crossover repeated measures design. WBV+RE exposed subjects to 5 one-minute bouts of vibration (20 Hz, 3.38 peak-peak displacement, separated by 1 min of rest) before RE. Fasting blood samples were obtained before (Pre), immediately after WBV (PostVib), immediately after RE (IP), and 30-min after RE (P30). Bone alkaline phosphatase did not change at any time point. Tartrate-resistant acid phosphatase 5b significantly increased (p<0.05) from the Pre to PostVib, then decreased from IP to P30 for both conditions. C-terminal telopeptide of type I collagen (CTX) significantly decreased (p<0.05) from Pre to PostVib and from Pre to P30 only for WBV+RE. WBV+RE showed a greater decrease in CTX than RE (-12.6% ± 4.7% vs -1.13% ± 3.5%). In conclusion, WBV was associated with acute decreases in CTX levels not elicited with RE alone in young women.
Bone Density Research Laboratory, Department of Health and Exercise Science, University of Oklahoma, Norman, OK 73019, USA.
Vanessa D
VD
Sherk
Carmen
C
Chrisman
Jessica
J
Smith
Kaelin C
KC
Young
Harshvardhan
H
Singh
Michael G
MG
Bemben
Debra A
DA
Bemben
D000328:Adult; D000469:Alkaline Phosphatase / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D001862:Bone Resorption / Q000503:physiopathology; D001842:Bone and Bones / Q000378:metabolism*; D024042:Collagen Type I / Q000378:metabolism; D018592:Cross-Over Studies; D005260:Female; D006400:Hematocrit; D006801:Humans; D019344:Lactic Acid / Q000097:blood; D053580:Muscle Strength / Q000502:physiology*; D010455:Peptides / Q000378:metabolism; D010812:Physical Stimulation; D055070:Resistance Training; D014732:Vibration / Q000627:therapeutic use; D055815:Young Adult
D015415:Biomarkers; D024042:Collagen Type I; D010455:Peptides; C052929:collagen type I trimeric cross-linked peptide; D019344:Lactic Acid; D000469:Alkaline Phosphatase