Tacrolimus-induced unilateral ischaemic optic neuropathy in a non-transplant patient.
Tacrolimus is commonly used as an immunosuppressant in organ transplantation. Although it is well tolerated, visual loss has been known as a rare but serious complication of this drug. We report a woman developing visual complaints while on tacrolimus therapy for nephrotic syndrome. Omission of the drug led to partial visual field recovery. Visual complications in patients receiving tacrolimus should alert the treating physicians for timely discontinuation of the drug.
Department of Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Monika
M
Gupta
Reema
R
Bansal
Nikhil
N
Beke
Amod
A
Gupta
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D009404:Nephrotic Syndrome / Q000188:drug therapy; D018917:Optic Neuropathy, Ischemic / Q000139:chemically induced* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D016559:Tacrolimus / Q000009:adverse effects*; D015354:Vision, Low / Q000139:chemically induced* / Q000188:drug therapy; D028761:Withholding Treatment
D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D011239:Prednisolone; D016559:Tacrolimus