Metastatic neuroendocrine carcinoma presenting as a "Superscan" on 68Ga-DOTANOC somatostatin receptor PET/CT.
PET/CT imaging using Ga-labeled somatostatin analogs has become a popular noninvasive diagnostic modality in the workup of patients with neuroendocrine tumors. A 65-year-old man with pancreatic neuroendocrine tumor with confirmed liver metastases on conventional imaging underwent restaging Ga-DOTANOC PET/CT to monitor response to cold octreotide therapy. Previous PET/CT had shown presence of multiple liver and skeletal metastases along with a primary pancreatic tumor showing intense tracer uptake. The present PET/CT study showed an increase in number and uptake of the metastatic lesions suggestive of progressive disease resulting in the appearance of a superscan.
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Niraj
N
Naswa
Sellam
S
Karunanithi
Ramya
R
Soundararajan
Kalpa Jyoti
KJ
Das
Krishan Kant
KK
Agarwal
Arun
A
Malhotra
Chandrasekhar
C
Bal
Rakesh
R
Kumar
D000368:Aged; D018278:Carcinoma, Neuroendocrine / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D009362:Neoplasm Metastasis; D009942:Organometallic Compounds; D049268:Positron-Emission Tomography; D017481:Receptors, Somatostatin / Q000378:metabolism*; D014057:Tomography, X-Ray Computed
C504894:68Ga-DOTANOC; D009942:Organometallic Compounds; D017481:Receptors, Somatostatin