Large enhancement of single molecule fluorescence by coupling to hollow silver nanoshells.
We investigated the effect of plasmon-enhanced fluorescence using hollow silver nanoshells and observed enhancement of a single probe's fluorescence up to a factor of 3 orders of magnitude. The enhancement of the quantum efficiency is attributed to enhanced absorption and increased radiative decay rate.
Department of Molecular Biology and Biochemistry, University of Maryland School of Medicine, 725 W. Lombard Street, Baltimore, MD 21201, USA. yfu@umaryland.edu
Yi
Y
Fu
Jian
J
Zhang
Joseph R
JR
Lakowicz
D005453:Fluorescence; D053768:Metal Nanoparticles / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry; D012834:Silver / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D020349:Surface Plasmon Resonance; D013499:Surface Properties
D012834:Silver; D012822:Silicon Dioxide