Acute glomerulonephritis in an immunocompetent elderly woman after contact with a child who had been diagnosed as erythema infectiosum.
The prevalence of postinfectious glomerulonephritis has decreased in most developed countries. We report the case of a previously healthy, immunocompetent 65-year-old woman who developed acute glomerulonephritis associated with human parvovirus B19 infection. She was referred by her primary care physician for suspected congestive heart failure but she had an elevated creatinine level and an abnormal urinalysis. Renal biopsy showed diffuse endocapillary proliferative glomerulonephritis. After biopsy, we learned that she had been in frequent contact with her grandson who had been diagnosed with erythema infectiosum. Her human parvovirus B19 serum IgM titer was elevated at 3.50, indicating current infection.
Department of Nephrology, Tokushima University Hospital, Japan. s_kishi@clin.med.tokushima-u.ac.jp
Seiji
S
Kishi
Satoshi
S
Yamada
Fumi
F
Kishi
Eriko
E
Shibata
Motokazu
M
Matsuura
Kojiro
K
Nagai
Akira
A
Mima
Hideharu
H
Abe
Toshio
T
Doi
D000208:Acute Disease; D000368:Aged; D003404:Creatinine / Q000097:blood; D018562:Disease Transmission, Infectious; D016731:Erythema Infectiosum / Q000635:transmission*; D005260:Female; D005921:Glomerulonephritis / Q000175:diagnosis / Q000276:immunology / Q000473:pathology / Q000821:virology*; D006801:Humans; D007121:Immunocompetence; D007668:Kidney / Q000276:immunology / Q000473:pathology; D007678:Kidney Glomerulus / Q000473:pathology; D016732:Parvovirus B19, Human / Q000302:isolation & purification
D003404:Creatinine