Coordination behavior of ligand based on NNS and NNO donors with ruthenium(III) complexes and their catalytic and DNA interaction studies.
Reactions of 2-acetylpyridine-thiosemicarbazone HL(1), 2-acetylpyridine-4-methyl-thiosemicarbazone HL(2), 2-acetylpyridine-4-phenyl-thiosemicarbazone HL(3) and 2-acetylpyridine-semicarbazone HL(4) with ruthenium(III) precursor complexes were studied and the products were characterized by analytical and spectral (FT-IR, electronic, EPR and EI-MS) methods. The ligands coordinated with the ruthenium(III) ion via pyridine nitrogen, azomethine nitrogen and thiolate sulfur/enolate oxygen. An octahedral geometry has been proposed for all the complexes based on the studies. All the complexes are redox active and display an irreversible and quasireversible metal centered redox processes. Further, the catalytic activity of the new complexes has been investigated for the transfer hydrogenation of ketones in the presence of isopropanol/KOH and the Kumada-Corriu coupling of aryl halides with aryl Grignard reagents. The DNA cleavage efficiency of new complexes has also been tested.
Department of Chemistry, Periyar University, Salem 636011, Tamilnadu, India.
R
R
Manikandan
P
P
Viswnathamurthi
D002384:Catalysis; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism*; D004269:DNA, Bacterial / Q000378:metabolism*; D004578:Electron Spin Resonance Spectroscopy; D004583:Electrons; D004587:Electrophoresis, Agar Gel; D004926:Escherichia coli / Q000378:metabolism; D006865:Hydrogenation; D007659:Ketones / Q000737:chemistry; D008024:Ligands; D008956:Models, Chemical; D009584:Nitrogen / Q000737:chemistry; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry* / Q000378:metabolism; D012545:Schiff Bases / Q000138:chemical synthesis / Q000737:chemistry; D021241:Spectrometry, Mass, Electrospray Ionization; D013055:Spectrophotometry, Infrared; D013455:Sulfur / Q000737:chemistry; D013882:Thiosemicarbazones / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism*
D056831:Coordination Complexes; D004269:DNA, Bacterial; D007659:Ketones; D008024:Ligands; D012545:Schiff Bases; D013882:Thiosemicarbazones; D013455:Sulfur; D012428:Ruthenium; D009584:Nitrogen; D010100:Oxygen