Meningoencephalitis with subdural empyema caused by toxigenic Clostridium perfringens type A.
We report a clinical case of meningoencephalitis with subdural empyema in an immunocompromised farmer caused by toxigenic Clostridium perfringens type A, which was identified by 16S RNA gene analysis of cerebrospinal fluid and subdural empyema. In immunocompromised patients, C. perfringens should be considered a potential pathogen of sepsis.
Department of Neurosurgery, University Hospital, Zurich, Switzerland.
Michael
M
Hugelshofer
Yvonne
Y
Achermann
Helen
H
Kovari
Wolfgang
W
Dent
Michael
M
Hombach
Guido
G
Bloemberg
D000368:Aged; D001427:Bacterial Toxins / Q000235:genetics*; D002555:Cerebrospinal Fluid / Q000382:microbiology; D003015:Clostridium Infections / Q000175:diagnosis* / Q000382:microbiology; D003016:Clostridium perfringens / Q000145:classification / Q000302:isolation & purification*; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D013354:Empyema, Subdural / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008590:Meningoencephalitis / Q000150:complications / Q000175:diagnosis*; D008969:Molecular Sequence Data; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA
D001427:Bacterial Toxins; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S