[Current concepts of the origin of circadian changes in the cardiovascular system under normal and pathological conditions].
The importance of circadian rhythms for the function of the cardiovascular system and its pharmacotherapy is discussed The central mechanisms regulating these rhythms at the level of suprachiasmatic hypothalamic nucleus and pineal gland are considered in conjunction with the approaches to modulating their activity for optimization of chronopharmnacotherapy of cardiovascular diseases.
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Arushanyan
D000818:Animals; D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology*; D002320:Cardiovascular Physiological Phenomena; D002319:Cardiovascular System / Q000503:physiopathology*; D002940:Circadian Rhythm / Q000235:genetics / Q000502:physiology*; D006801:Humans; D051381:Rats