Ictal and interictal 99mTc-HMPAO brain SPECT of a MELAS case presented with epilepsy-like visual hallucination.
A 55-year-old woman was diagnosed with the syndrome of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). She was referred for Tc-HMPAO brain SPECT because of visual hallucinations, which were suspected to be related to epileptic seizures. Ictal SPECT images showed remarkable hyperperfusion in the left occipital cortex, which returned to near-normal status on the interictal SPECT images after treatment with anticonvulsants. It is very rare to see such an ictal SPECT image of epileptic or epilepsy-like disorders, especially in the setting of MELAS syndrome with visual hallucination.
Department of Nuclear Medicine, Chang Bing Show Chwan Hospital, 6 Lukon Rd, Lukong Town, Changhua Shien, Taiwan 505, Taiwan. 106143@gmail.com
Cheng-Yu
CY
Wei
Heng-Long
HL
Hsiao
Shang-Chi
SC
Chen
Guang-Uei
GU
Hung
Chia-Hung
CH
Kao
D001921:Brain / Q000000981:diagnostic imaging*; D004827:Epilepsy / Q000150:complications*; D005260:Female; D006212:Hallucinations / Q000150:complications*; D006801:Humans; D017241:MELAS Syndrome / Q000150:complications* / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D008875:Middle Aged; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
D019690:Technetium Tc 99m Exametazime