Thrombosis of portal venous system after laparoscopic cholecystectomy in a patient with prothrombin gene mutation.
Laparoscopic cholecystectomy is now the gold standard for the treatment of symptomatic cholelithiasis. Portal venous thrombosis after laparoscopic cholecystectomy is rare. We report a case of thrombosis of the portal venous system after laparoscopic cholecystectomy in a patient with  a latent prothrombin gene mutation. An abdominal computed tomography and magnetic resonance angiogram of the abdomen revealed portal, superior mesenteric, and splenic vein thrombosis. Testing for coagulation disorders showed a heterozygous form of factor II (prothrombin) G20210A mutation.  Because of its rarity, information regarding this complication is limited.
Wright State University, Boonshoft School of Medicine, Dayton, OH, USA.
Waheed
W
Gul
Khurram
K
Abbass
Arif M
AM
Qazi
Ronald J
RJ
Markert
Christopher J
CJ
Barde
D017081:Cholecystectomy, Laparoscopic; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008875:Middle Aged; D009154:Mutation; D011169:Portal Vein; D011516:Prothrombin / Q000235:genetics*; D013162:Splenic Vein; D020246:Venous Thrombosis / Q000235:genetics*
D011516:Prothrombin