Elevated iodine uptake at autogenous bone graft harvest sites.
A 16-year-old adolescent girl post total thyroidectomy for papillary thyroid carcinoma presented for postsurgical radioablative therapy. A whole-body I scintigraphy revealed not only expected activity in the thyroid bed but also asymmetric tracer distribution in the mandible and 2 foci of increased I accumulation in the distal left lower extremity. SPECT/CT images localized the activity to the donor sites of an autologous left fibular bone graft, harvested 8 years earlier to repair her mandible. Our case demonstrates that iodine accumulation can occur at the site of bone surgery many years after intervention and should be differentiated from iodine-avid metastases.
Department of Nuclear Medicine, Beijing Friendship Hospital of Capital Medical University, Beijing, China.
Jigang
J
Yang
Ion
I
Codreanu
Sabah
S
Servaes
Hongming
H
Zhuang
D000293:Adolescent; D001692:Biological Transport; D016025:Bone Transplantation; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000378:metabolism*; D002291:Carcinoma, Papillary; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000378:metabolism; D011877:Radionuclide Imaging; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism*
D007457:Iodine Radioisotopes