Acupuncture relieves menopausal discomfort in breast cancer patients: a prospective, double blinded, randomized study.
BACKGROUND
This study evaluates the effect of acupuncture on hot flashes and disturbed night sleep in patients treated for breast cancer. The effect of acupuncture was tested against a sham-acupuncture group and a no-treatment control group. Plasma estradiol was measured to rule out this as cause of effect. Side effects of the treatment were registered.


METHODS
We randomized 94 women into the study: 31 had acupuncture, 29 had sham acupuncture and 34 had no treatment.


RESULTS
In the acupuncture group, 16 patients (52%) experienced a significant effect on hot flashes compared with seven patients (24%) in the sham group (p < 0.05). The effect came after the second acupuncture session and lasted for at least 12 weeks after last treatment. A statistically significant positive effect was seen on sleep in the acupuncture group compared with the sham-acupuncture and no-treatment groups. The effect was not correlated with increased levels of plasma estradiol. No side effects of acupuncture were registered.


CONCLUSIONS
We find that acupuncture significantly relieves hot flashes and sleep disturbances and is a good and safe treatment in women treated for breast cancer.
Department of Breast Surgery, Vejle Hospital, Denmark. sbok0003@heh.regionh.dk
Susanne
S
Bokmand
Henrik
H
Flyger
D015670:Acupuncture Therapy / Q000009:adverse effects; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000150:complications* / Q000188:drug therapy; D017024:Chemotherapy, Adjuvant; D004311:Double-Blind Method; D004958:Estradiol / Q000097:blood; D005260:Female; D019584:Hot Flashes / Q000150:complications / Q000628:therapy*; D006801:Humans; D008593:Menopause / Q000097:blood; D008875:Middle Aged; D012893:Sleep Wake Disorders / Q000150:complications / Q000628:therapy*
D000970:Antineoplastic Agents; D004958:Estradiol