[Analysis of saponins in Panax notoginseng by UPLC-LTQ-Orbitrap MS/MS].
A method for qualitative analysis of constituents in Panax notoginseng by UPLC-LTQ-Orbitrap mass spectrometry was established. Based on the high-resolution mass information, MS/MS fragmentation behaviors and chemical components from literatures, 43 compounds were identified or tentatively characterized. New type saponin aglycone, combined with malonyl-substituted and acetyl-substituted saponins were discovered and plausibly identified in this study. This work could be helpful for the quality control and further phytochemical studies of Panax notoginseng, and provided a good example for the analysis of chemical constituents in traditional Chinese medicine.
The Second College of Clinic Medicine, Guangzhou University of Chinese Medicine, Guangdong Province Institute of Chinese Medicine, Guangzhou 510006, China.
Wen
W
Xu
Xiao-Hui
XH
Qiu
Jing
J
Zhang
Da-Yuan
DY
Zhu
Yi-Ming
YM
Yang
Chuan-Jian
CJ
Lu
D002851:Chromatography, High Pressure Liquid; D005583:Fourier Analysis; D036145:Ginsenosides / Q000032:analysis*; D053723:Panax notoginseng / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D011786:Quality Control; D012503:Saponins / Q000032:analysis* / Q000145:classification; D053719:Tandem Mass Spectrometry
D036145:Ginsenosides; D012503:Saponins; C487685:notoginsenoside R2; C072936:notoginsenoside R1