Middle cerebral artery involvement in systemic lupus erythematosus presenting as a stroke--an unusual initial presentation of the disease.
Systemic lupus erythematosus (SLE) disproportionately affects the African American population and usually presents with a constellation of symptoms. Along with hematologic, musculoskeletal, serous and skin involvement, the most common causes of morbidity are attributed to altered blood rheology causing accelerated atherosclerotic vascular disease (ASVD). ASVD occurs in predominantly premenopausal women at an age where ASVD is rare or uncommon. Classical central nervous system manifestations are very rare from the outset of the disease. Here we present a 44-year old African American woman with newly diagnosed SLE and no significant atherosclerotic risk factors, who presented initially with symptoms of subacute stroke.
Mount Sinai School of Medicine/Queens Hospital Center, New York, NY 11432, USA. panagiotis.sideras@mssm.edu
Panagiotis A
PA
Sideras
Joel
J
Jacob
Amitasha
A
Mann
Jaswinder
J
Singh
Rino
R
Buzzola
Adriana
A
Abrudescu
D000328:Adult; D003937:Diagnosis, Differential; D056324:Diffusion Tensor Imaging; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis; D018810:Magnetic Resonance Angiography; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging / Q000473:pathology*; D009141:Musculoskeletal System / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D020521:Stroke / Q000150:complications* / Q000175:diagnosis