Metal catalyzed C(sp3)-H bond amination of 2-alkyl azaarenes with diethyl azodicarboxylate.
Metal-catalyzed direct C(sp(3))-H bond amination of 2-alkyl azaarenes with N=N double bonds has been developed, which expands the scope of C(sp(3))-H bond activation reactions and provides a new access to medicinally important azaarene derivatives.
College of Chemistry and Environmental Science, Key Laboratory of Green Chemical Media and Reactions of Ministry of Education, Henan Normal University, Xinxiang 453007, Henan, China.
Jin-Ying
JY
Liu
Hong-Ying
HY
Niu
Shan
S
Wu
Gui-Rong
GR
Qu
Hai-Ming
HM
Guo
D000586:Amination; D001372:Aza Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D001391:Azo Compounds / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D006860:Hydrogen Bonding; D019216:Metals, Heavy / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*
D001372:Aza Compounds; D001391:Azo Compounds; D002264:Carboxylic Acids; D019216:Metals, Heavy; D009942:Organometallic Compounds