Correlation of temperature rise and optical coherence tomography characteristics in patient retinal photocoagulation.
We conducted a study to correlate the retinal temperature rise during photocoagulation to the afterward detected tissue effect in optical coherence tomography (OCT). 504 photocoagulation lesions were examined in 20 patients. The retinal temperature increase was determined in real-time during treatment based on thermoelastic tissue expansion which was probed by repetitively applied ns laser pulses. The tissue effect was examined on fundus images and OCT images of individualized lesions. We discerned seven characteristic morphological OCT lesion classes. Their validity was confirmed by increasing visibility and diameters. Mean peak temperatures at the end of irradiation ranged from approx. 60 °C to beyond 100 °C, depending on burn intensity.
Department of Ophthalmology, University of Kiel, Kiel, Germany. Koinzer@auge.uni-kiel.de
Stefan
S
Koinzer
Kerstin
K
Schlott
Lea
L
Portz
Lars
L
Ptaszynski
Alexander
A
Baade
Marco
M
Bever
Mark
M
Saeger
Amke
A
Caliebe
Renè
R
Denner
Reginald
R
Birngruber
Ralf
R
Brinkmann
Johann
J
Roider
D023381:Endpoint Determination; D005128:Eye Diseases / Q000473:pathology / Q000601:surgery; D006801:Humans; D017075:Laser Coagulation / Q000295:instrumentation / Q000379:methods*; D009887:Ophthalmoscopy; D012160:Retina / Q000473:pathology / Q000601:surgery*; D013696:Temperature; D041623:Tomography, Optical Coherence