Biotransformation of serotonin derivatives by the larvae of common cutworm (Spodoptera litura).
Seven serotonin derivatives (1-7) were biotransformed using larvae of Spodoptera litura. N-p-methoxy cinnamoyl serotonin (3) was converted into its O-demethylated compound, N-p-coumaroyl serotonin (2). Furthermore, N-feruloyl serotonin (5) and N-isoferuloyl serotonin (6) were converted into, two new compounds, N-feruloyl serotonin-4'-O-β-D-glucopyranoside (8) and N-isoferuloyl serotonin-3'-O-β-D-glucopyranoside (9), respectively. These structures were established by IR, 1D-NMR and 2D-NMR spectral studies.
Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, 3-4-1 Kowakae, Higashiosaka-shi, Osaka 577-8502, Japan.
Toshiyuki
T
Takahashi
Mitsuo
M
Miyazawa
D000818:Animals; D007814:Larva / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D012701:Serotonin / Q000378:metabolism*; D018411:Spodoptera / Q000378:metabolism*
D012701:Serotonin; C114774:N-(p-coumaroyl)serotonin