A case of multimodality multiparametric 11C-choline PET/MR for biopsy targeting in prior biopsy-negative primary prostate cancer.
We introduce the case of a 70-years-old man with an elevated level of prostate-specific antigen and prior negative biopsy. For targeting rebiopsy, the patient underwent C-choline PET/CT and subsequent PET/MR. Both the high uptake in PET and the abnormal findings in MR gave strong evidence for prostate cancer at the ventral periphery of the right apex. This location is sometimes not covered by routine sextant biopsy. The following targeted rebiopsy was positive for prostate cancer. This case indicates the potential role of PET/MR for identifying primary prostate cancer because of its high soft tissue contrast and the possibility of a multimodality approach.
Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany. toshive@med.hokudai.ac.jp
Toshiki
T
Takei
Michael
M
Souvatzoglou
Ambros J
AJ
Beer
Alexander
A
Drzezga
Sybille
S
Ziegler
Ernst J
EJ
Rummeny
Markus
M
Schwaiger
Matthias
M
Eiber
D000368:Aged; D001706:Biopsy / Q000379:methods*; D002250:Carbon Radioisotopes; D002794:Choline; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D049268:Positron-Emission Tomography; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology*
D002250:Carbon Radioisotopes; D002794:Choline