Unifying metastasis--integrating intravasation, circulation and end-organ colonization.
Recent technological advances that have enabled the measurement of circulating tumour cells (CTCs) in patients have spurred interest in the circulatory phase of metastasis. Techniques that do not solely rely on a blood sample allow substantial biological interrogation beyond simply counting CTCs.
Integrated Mathematical Oncology, Moffitt Cancer Center, Tampa, Florida 33612, USA. jacob.scott@moffitt.org
Jacob
J
Scott
Peter
P
Kuhn
Alexander R A
AR
Anderson
D001775:Blood Circulation / Q000502:physiology*; D006801:Humans; D009362:Neoplasm Metastasis / Q000473:pathology* / Q000503:physiopathology*; D009360:Neoplastic Cells, Circulating / Q000473:pathology*