Gauze-based negative pressure wound therapy: a valid method to manage pyoderma gangrenosum.
Pyoderma gangrenosum (PG) is an uncommon ulcerative, non-infective chronic inflammatory skin disorder of unknown aetiology. Systemic therapies are necessary to control the associated medical diseases, and, due to the inflammatory nature of PG, topical or systemic immunosuppressant agents are effective, but wound healing is usually slow. Negative wound pressure therapy (NPWT) has become an important tool for the management of complex skin ulcers, and usage in PG has been recently described in the literature: we present four cases of classic PG in which NPWT in association with systemic therapy achieved wound healing and a drastic pain reduction.
Plastic Surgery Department, University of Turin, San Giovanni Battista di Torino, Via Cherasco 23, Turin, ItalyDepartment of Biomedical Sciences and Human Oncology, Section of Dermatology, University of Turin, San Giovanni Battista di Torino, Via Cherasco 23, Turin, Italy.
Marco
M
Fraccalvieri
Maria Teresa
MT
Fierro
Marco
M
Salomone
Paolo
P
Fava
Enrico M
EM
Zingarelli
Giovanni
G
Cavaliere
Maria G
MG
Bernengo
Stefano
S
Bruschi
D000368:Aged; D001941:Breast Diseases / Q000628:therapy; D016572:Cyclosporine / Q000008:administration & dosage; D003879:Dermatologic Agents / Q000008:administration & dosage; D005260:Female; D006097:Granulation Tissue; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D054843:Negative-Pressure Wound Therapy / Q000379:methods; D010146:Pain / Q000517:prevention & control; D010147:Pain Measurement; D017511:Pyoderma Gangrenosum / Q000628:therapy*; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology
D003879:Dermatologic Agents; D007166:Immunosuppressive Agents; D016572:Cyclosporine