Improving outcomes for composite grafts in nasal reconstruction.
OBJECTIVE
Auricular composite grafting is a useful technique for the reconstruction of select nasal defects. However, unpredictable graft survival has been the primary limitation of this technique. The literature was reviewed to evaluate the effectiveness of various surgical, pharmacologic, hyperbaric, and hypothermic interventions to improve composite graft survival.


RESULTS
Although no statistically significant surgical interventions were found, several techniques appear promising. There are a number of studies demonstrating the beneficial effects of perioperative and postoperative corticosteroid administration. Other agents studied have had modest to no benefit. Hyperbaric oxygen therapy holds promise but the expense, practicality, and lack of an established optimal treatment protocol remain obstacles to routine use.


CONCLUSIONS
The use of corticosteroids and postoperative cooling are relatively inexpensive and effective modalities to improve auricular composite graft survival when used for nasal reconstruction. Hyperbaric oxygen therapy may have a role, but more research is needed before it is employed routinely.
Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
John M
JM
Harbison
J David
JD
Kriet
Clinton D
CD
Humphrey
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000818:Animals; D002356:Cartilage / Q000637:transplantation*; D004195:Disease Models, Animal; D006085:Graft Survival / Q000187:drug effects / Q000502:physiology; D006801:Humans; D006931:Hyperbaric Oxygenation; D007036:Hypothermia, Induced; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control*; D011300:Preoperative Care / Q000379:methods; D012225:Rhinoplasty / Q000379:methods*; D016038:Skin Transplantation / Q000379:methods*; D040521:Subcutaneous Tissue / Q000637:transplantation*; D020858:Tissue and Organ Harvesting / Q000379:methods
D000305:Adrenal Cortex Hormones