Transient tonic upgaze deviation: a neuro-ophthalmological complication of acute cerebellitis.
Acute cerebellitis in children is an inflammatory syndrome with symptoms of cerebellar dysfunction. We describe a 3-year-old boy with acute cerebellitis who had cerebellar tonsillar herniation, hydrocephalus, and transient tonic bilateral upward gaze deviation. Although no etiology for his acute cerebellitis was determined, he fully recovered with high-dose corticosteroids, intravenous immunoglobulin, and antimicrobial therapy. We propose that there was tonic irritation of the upward gaze generator cells in the superior colliculus as an explanation for temporary disturbance of his ocular gaze.
Division of Child and Adolescent Neurology, Department of Pediatrics, The University of Texas Health Science Center, Houston, TX 77030, USA.
Jeremy
J
Lankford
Ian J
IJ
Butler
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002526:Cerebellar Diseases / Q000150:complications*; D002675:Child, Preschool; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D015835:Ocular Motility Disorders / Q000188:drug therapy / Q000209:etiology*; D013477:Superior Colliculi / Q000187:drug effects / Q000473:pathology; D014057:Tomography, X-Ray Computed
D000305:Adrenal Cortex Hormones; D000890:Anti-Infective Agents; D016756:Immunoglobulins, Intravenous