[The effect of mixed cultivation of lymphocytes irradiated at a dose of 1 Gy and non-irradiated lymphocytes on the frequency of chromosomal aberration].
The mutual influence of irradiated (1 Gy) and non-irradiated cells was demonstrated on the model of the mixed culture oflymphocytes from opposite gender donors using chromosome aberrations (ChA) as an endpoint. The number of ChA in non-irradiated lymphocytes in mixed cultures with irradiated ones increased as compared to the corresponding monocultures. At the same time, the number of induced ChA decreased in the irradiated lymphocytes cultivated with non-irradiated ones.
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Kolesnikova
D000328:Adult; D024201:Bystander Effect; D018929:Cell Culture Techniques; D002478:Cells, Cultured; D002869:Chromosome Aberrations / Q000528:radiation effects* / Q000706:statistics & numerical data*; D018920:Coculture Techniques; D005260:Female; D005720:Gamma Rays / Q000009:adverse effects*; D006801:Humans; D008214:Lymphocytes / Q000473:pathology / Q000528:radiation effects*; D008297:Male; D011829:Radiation Dosage; D012727:Sex Characteristics