EPR studies on Fcgamma receptor-mediated changes in lymphocyte membrane.
Biophysical evidence has been presented for the interaction of human lymphocyte membrane Fc receptors with aggregated IgG by severely restricting the rotational mobility of the cell surface proteins, as well as membrane lipids. Decrease in membrane fluidity was more prominent with aggregated IgG since the multivalency of Fc regions in aggregated IgG cross-linked cell surface Fc receptor.
School of Life Sciences, Devi Ahilya Vishwavidyalaya, Vigyan Bhawan, Khandwa Road Campus, Indore 452 001 (MP), India.
Rajesh K
RK
Gupta
Abhay H
AH
Pande
Sumati
Krishnan
K
Hajela
D002462:Cell Membrane / Q000378:metabolism*; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods*; D006801:Humans; D008214:Lymphocytes / Q000166:cytology*; D017452:Receptors, IgG / Q000378:metabolism*
D017452:Receptors, IgG