Exaggerated placental site reaction detected during caesarean delivery: a case report.
Exaggerated placental site (EPS) reaction is an exuberant physiologic process in which intermediate trophoblasts infiltrate the underlying endometrium and myometrium at the implantation site. During a caesarean section, we noted a polypoid well shaped smooth lesion, about 3 cm in diameter on the anterior wall of the uterus apart from the placenta. The histopathologic examination revealed an exuberant proliferation of trophoblastic cells in the placental site, a low Ki-67 labelling index and the absence of mitotic activity. Distinguishing EPS reaction from the other intermediate trophoblastic tumours is critical, as the latter may likely involve surgical intervention and/or chemotherapy, although no specific treatment and follow-up is required for EPS reaction. It is necessary to be aware of this pathology and take biopsies from suspicious lesions in the placental site for pathologic examination.
Department of Obstetrics and Gynecology, Kanuni Sultan Suleyman Research and Teaching Hospital, Turkey.
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O
Akbayir
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I
Alkis
A
A
Corbacioglu
A
A
Ekiz
A
A
Akca
S
S
Cekic
D000328:Adult; D049109:Cell Proliferation; D017604:Cesarean Section, Repeat; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D019394:Ki-67 Antigen / Q000378:metabolism; D016311:Outliers, DRG; D010920:Placenta / Q000473:pathology*; D011247:Pregnancy; D018245:Trophoblastic Tumor, Placental Site / Q000473:pathology*; D014327:Trophoblasts / Q000378:metabolism*; D014594:Uterine Neoplasms
D019394:Ki-67 Antigen