Optical parameters of embedded abnormalities in tissues as determined by Monte Carlo simulation.
Photon propagation through tissue phantoms, made of heart, adipose, and spleen tissues was simulated by Monte Carlo procedure. To detect the presence of deep-seated abnormalities, phantoms of heart with adipose and spleen tissues embedded into it were created and simulations were performed to scan the tissue surface with a source and four detector model. Profiles drawn showed variation in parameters such as backscattered intensity in regions where adipose and spleen tissues were embedded. This study shows that depending on the type of embedded tissue the backscattered fraction as measured at 2 mm from the input fiber is altered. This is enhanced for adipose and decreased for spleen tissue. This is not only shown in scanned profiles on the surface but also in constructed images.
Biomedical Engineering Division, School of Biosciences and Biotechnology, V.I.T. University, Vellore-632014, India.
J B
JB
Jeeva
Megha
M
Singh
D000818:Animals; D006041:Goats; D009010:Monte Carlo Method; D055620:Optical Phenomena; D009928:Organ Specificity; D019047:Phantoms, Imaging; D017785:Photons; D012542:Scattering, Radiation