A rhodium complex-linked β-barrel protein as a hybrid biocatalyst for phenylacetylene polymerization.
Our group recently prepared a hybrid catalyst containing a rhodium complex, Rh(Cp)(cod), with a maleimide moiety at the peripheral position of the Cp ligand. This compound was then inserted into a β-barrel protein scaffold of a mutant of aponitrobindin (Q96C) via a covalent linkage. The hybrid protein is found to act as a polymerization catalyst and preferentially yields trans-poly(phenylacetylene) (PPA), although the rhodium complex without the protein scaffold normally produces cis PPA.
Department of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
Akira
A
Onoda
Kazuki
K
Fukumoto
Marcus
M
Arlt
Marco
M
Bocola
Ulrich
U
Schwaneberg
Takashi
T
Hayashi
D000114:Acetylene / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism; D055162:Biocatalysis; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D050505:Mutant Proteins / Q000737:chemistry* / Q000378:metabolism*; D009154:Mutation; D009942:Organometallic Compounds / Q000737:chemistry / Q000378:metabolism*; D058105:Polymerization; D012238:Rhodium / Q000737:chemistry*
D050505:Mutant Proteins; D009942:Organometallic Compounds; C044736:phenylacetylene; D012238:Rhodium; D000114:Acetylene