[Laboratory diagnostics for early detection of rheumatic autoimmune diseases: a guide for the general practitioner].
Autoimmune diseases are a clinically heterogeneous group of disorders that represent a challenge for the general practitioner in daily routine. Except for rheumatoid arthritis, which is one of the most frequent autoimmune diseases with a prevalence of approximately 1 % of the population, systemic autoimmune disorders are rare. Thus outside specialized wards it might be a challenge to diagnose the underlying autoimmune disease considering the often kaleidoscopic clinical manifestations. Together with careful anamnesis and suspicious clinical symptoms determination of specific autoantibodies can support the suspected diagnosis. The Austrian group of the European autoimmune standardization initiative (EASI) firstly published this guide 2009 with the aim to provide a map through the jungle of the biomarkers for autoimmune diseases for the general practitioner.
Zentrallabor, Wilhelminenspital der Stadt Wien, Wien, Österreich. georg.endler@meduniwien.ac.at
Georg
G
Endler
Ulrike
U
Demel
Ernst
E
Forster
Andrea
A
Griesmacher
Christin
C
Hübner
Werner
W
Klotz
Günter
G
Steiner
W
W
Wagner
Manfred
M
Herold
D000293:Adolescent; D000328:Adult; D001172:Arthritis, Rheumatoid / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology; D001317:Austria; D001323:Autoantibodies / Q000097:blood*; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology; D015415:Biomarkers / Q000097:blood*; D002648:Child; D003299:Cooperative Behavior; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D058006:General Practice; D006801:Humans; D033183:Interdisciplinary Communication; D012216:Rheumatic Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology
D001323:Autoantibodies; D015415:Biomarkers