High-throughput optofluidic platforms for mosaicked microfibers toward multiplex analysis of biomolecules.
We describe high-throughput optofluidic platforms for mosaic-patterned microfibers by generating stratified laminar flows. An inert carrier liquid flow near PDMS channel walls conveyed a photopolymerizable liquid which permitted stable production of microfibers with particular morphologies and compositional patterns. Finally, mosaicked microfibers were prepared with desired configurations toward multiplex biomolecular analysis.
Department of Chemical and Biomolecular Engineering, KAIST, National Creative Research Initiative Center for Integrated Optofluidic Systems, Daejeon, 305-701, Korea.
Soojeong
S
Cho
Tae Soup
TS
Shim
Seung-Man
SM
Yang
D000818:Animals; D000906:Antibodies / Q000276:immunology; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D016650:Fluorescein-5-isothiocyanate / Q000737:chemistry; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry; D007074:Immunoglobulin G / Q000032:analysis / Q000276:immunology; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*; D018613:Microscopy, Confocal; D055095:Optics and Photonics / Q000295:instrumentation*; D011817:Rabbits
D000906:Antibodies; D004129:Dimethylpolysiloxanes; D007074:Immunoglobulin G; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; C013830:baysilon; D016650:Fluorescein-5-isothiocyanate