Palladium-catalyzed cross-coupling reactions of electron-deficient alkenes with N-tosylhydrazones: functional-group-controlled C-C bond construction.
In the zone: A palladium-catalyzed cross-coupling reaction of electron-deficient alkenes with N-tosylhydrazones, which affords diverse C-C bonds resulting from the functional-group-controlled effect, is reported (see scheme). These cascade transformations present remarkable stereoselectivity and a high synthetic potential. The presence of water substantially promotes both reaction routes.
School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, PR China. jianghf@scut.edu.cn
Huanfeng
H
Jiang
Wei
W
Fu
Huoji
H
Chen
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003432:Cross-Linking Reagents / Q000737:chemistry*; D003521:Cyclopropanes / Q000737:chemistry*; D004583:Electrons; D006835:Hydrazones / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D014105:Tosyl Compounds / Q000737:chemistry*
D000475:Alkenes; D003432:Cross-Linking Reagents; D003521:Cyclopropanes; D006835:Hydrazones; D014105:Tosyl Compounds; D010165:Palladium