Down syndrome DSCR1 causes spine pathology via the Fragile X-related protein FMRP.
Friedrich Miescher Institute for Biological Research, Basel, Switzerland. francesco.roselli@fmi.ch
Francesco
F
Roselli
D000818:Animals; D004268:DNA-Binding Proteins; D049229:Dendritic Spines / Q000378:metabolism*; D051860:Fragile X Messenger Ribonucleoprotein 1 / Q000502:physiology*; D005786:Gene Expression Regulation; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000502:physiology*; D009124:Muscle Proteins / Q000502:physiology*
D004268:DNA-Binding Proteins; D051860:Fragile X Messenger Ribonucleoprotein 1; D047908:Intracellular Signaling Peptides and Proteins; D009124:Muscle Proteins; C108612:RCAN1 protein, human