Absorption spectral study of 3, 4-dihydroxy phenyl alanine (DOPA) with Nd (III) in aqueous medium.
Spectroscopic properties of Nd (III)-DOPA in aquated organic solvents are investigated through absorption difference and comparative absorption spectroscopy involving 4f-4f transitions. The change in coordination in different conditions is observed from the absorption intensity analysis when Nd (III) interacts with DOPA. The interaction induced substantial changes in the intensities of 4f-4f bands and their perturbation was reflected through oscillator strength Judd-Ofelt intensity (Tlamda) parameters. It is suggested that the changes in the oscillator strengths of different 4f-4f bands and Judd-Ofelt intensity (Tlamda) parameters can be used to predict in vivo intracellular complexation of DOPA with Ca(II) through Nd (III)-DOPA absorption spectral studies in-vitro as both Nd (III) and Ca(II) have unique similarity in their coordination behaviour.
Department of Chemistry, Bhavnagar University, Bhavnagar 364 002, India. pnbchem@hotmail.com
Prashant N
PN
Bhatt
Trupti V
TV
Pathak
Jignasu P
JP
Mehta
Sudhindra N
SN
Misra
D000042:Absorption; D002623:Chemistry Techniques, Analytical; D004295:Dihydroxyphenylalanine / Q000031:analogs & derivatives* / Q000737:chemistry; D004583:Electrons; D007700:Kinetics; D008956:Models, Chemical; D009354:Neodymium / Q000737:chemistry*; D009991:Oscillometry / Q000379:methods; D011485:Protein Binding; D013053:Spectrophotometry / Q000379:methods*; D014867:Water / Q000737:chemistry
D014867:Water; C043437:fluorodopa F 18; D009354:Neodymium; D004295:Dihydroxyphenylalanine