40-De-oxy-40(S)-iodo-rapamycin.
The title compound, C(51)H(78)INO(12), contains a 29-membered ring incorporating amide, lactone and ester groups. It contains a total of 15 stereogenic centres. In the crystal, mol-ecules are linked by O-H⋯O hydrogen bonds, forming C(8) chains propagating in [100]. A weak intra-molecular O-H⋯O inter-action also occurs.
Lijun
L
Xie
Jian
J
Zuo
Guoxin
G
Yang
Congshen
C
Zheng
Yuanrong
Y
Cheng