Desorption ElectroSpray Ionization - Orbitrap Mass Spectrometry of synthetic polymers and copolymers.
Desorption ElectroSpray Ionization (DESI) - Orbitrap Mass Spectrometry (MS) was evaluated as a new tool for the characterization of various industrial synthetic polymers (poly(ethylene glycol), poly(propylene glycol), poly(methylmethacrylate), poly(dimethylsiloxane)) and copolymers, with masses ranging from 500 g.mol(-1) up to more than 20 000 g.mol(-1) . Satisfying results in terms of signal stability and sensitivity were obtained from hydrophobic surfaces (HTC Prosolia) with a mixture water/methanol (10/90) as spray solvent in the presence of sodium salt. Taking into account the formation of multiplied charged species by DESI-MS, a strategy based on the use of a deconvolution software followed by the automatic assignment of the ions was described allowing the rapid determination of M(n) , M(w) and PDI values. DESI-Orbitrap MS results were compared to those obtained from matrix-assisted laser desorption/ionization- time-of-flight MS and gel permeation chromatography. An application of DESI-Orbitrap MS for the detection and identification of polymers directly from cosmetics was described.
Université d'Evry val d'Essonne, Laboratoire Analyse et Modélisation pour la Biologie et l'Environnement, (CNRS UMR 8587/CEA), Bâtiment Maupertuis, Bd. François Mitterrand, 91025, Evry, France.
Manel
M
Friia
Véronique
V
Legros
Jeanine
J
Tortajada
William
W
Buchmann
D002850:Chromatography, Gel; D003358:Cosmetics / Q000737:chemistry; D057927:Hydrophobic and Hydrophilic Interactions; D007477:Ions / Q000032:analysis / Q000737:chemistry; D011108:Polymers / Q000032:analysis / Q000737:chemistry*; D012680:Sensitivity and Specificity; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*
D003358:Cosmetics; D007477:Ions; D011108:Polymers