Different genetic supports for the tet(S) gene in Enterococci.
The diversity of tet(S) genetic contexts of 13 enterococci from human, animal, and environmental samples from different geographical areas is reported. The tet(S) gene was linked to either CTn6000 variants of chromosomal location or composite platforms flanked by IS1216 located on plasmids (∼40 to 115 kb). The comparative analysis of all tet(S) genetic elements available in the GenBank databases suggests that CTn6000 might be the origin of a variety of tet(S)-carrying platforms that were mobilized to different plasmids.
REQUIMTE, Faculdade Farmácia. Universidade do Porto, Porto, Portugal. canos2@gmail.com
Carla
C
Novais
Ana R
AR
Freitas
Eduarda
E
Silveira
Fernando
F
Baquero
Luísa
L
Peixe
Adam P
AP
Roberts
Teresa M
TM
Coque
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial; D004251:DNA Transposable Elements; D030541:Databases, Genetic; D016983:Enterococcus / Q000145:classification / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D005798:Genes, Bacterial; D006801:Humans; D010957:Plasmids; D017422:Sequence Analysis, DNA; D013753:Tetracycline Resistance / Q000235:genetics*; D013754:Tetracyclines / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D004251:DNA Transposable Elements; D013754:Tetracyclines