The role of 26S proteasome-dependent proteolysis in the formation and restructuring of microtubule networks.
In this review, we summarize the evidence pointing at the important role of 26S proteasome-dependent proteolysis in the regulation of microtubule synthesis and microtubule dynamics. Because most of the advances in this relatively unexplored research field originate from yeast and animal studies, we have considered those studies that describe the role of proteolysis in processes that are evolutionarily conserved and known to exist in plants. In addition, we place particular emphasis on the proteasome-dependent degradation of plant-specific microtubule-associated protein SPIRAL1 and its function in MT rearrangements associated with salt stress.
Plant Physiology, Biochemistry and Molecular Biology Program, Department of Plant and Soil Sciences, University of Kentucky, Lexington, KY, USA.
Jasmina
J
Kurepa
Songhu
S
Wang
Jan
J
Smalle
D008870:Microtubules / Q000378:metabolism*; D008954:Models, Biological; D046988:Proteasome Endopeptidase Complex / Q000378:metabolism*; D059748:Proteolysis; D013312:Stress, Physiological; D014404:Tubulin / Q000378:metabolism
D014404:Tubulin; D046988:Proteasome Endopeptidase Complex; C061553:ATP dependent 26S protease