Bioactive phenolic compounds from the Egyptian Red Sea seagrass Thalassodendron ciliatum.
Five flavonoids (rutin, asebotin, 3-hydroxyasebotin, quercetin-3-O-beta-D-xylopyranoside, and a racemic mixture of catechin) and caffeic acid were isolated and identified for the first time from seagrass, Thalassodendron ciliatum, collected from the Hurghada region in Egypt. The crude extract and the isolated pure compounds were evaluated for their cytotoxic activities against HCT-116, HEPG, MCF-7, and HeLa human cancer cell lines, for their antiviral activity against Herpes Simplex and hepatitis A viruses, and for their antioxidant activity.
Chemistry of Natural and Microbial Products Department, National Research Centre, Cairo, Egypt.
Abdel-Hamid A
AH
Hamdy
Walaa S A
WS
Mettwally
Mohamed Abou
MA
El Fotouh
Benjamin
B
Rodriguez
Ahmed I
AI
El-Dewany
Sayed A A
SA
El-Toumy
Ahmed A
AA
Hussein
D035961:Alismatales / Q000737:chemistry*; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology; D000998:Antiviral Agents / Q000302:isolation & purification / Q000494:pharmacology; D045744:Cell Line, Tumor; D004534:Egypt; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D009792:Oceans and Seas; D010636:Phenols / Q000302:isolation & purification* / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet
D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D000998:Antiviral Agents; D010636:Phenols