Age at menopause, motives for consultation and symptoms reported by 40-59-year-old Mexican women.
OBJECTIVE
To assess the mean age at natural menopause, primary initial motives for consultation, symptoms and factors related to a more severe symptom profile using the Menopause Rating Scale (MRS) in a nationwide sample of middle-aged women in gynecological clinics in Mexico.


METHODS
A total of 4548 women, 40-59 years old were surveyed in gynecological clinics throughout all regions in Mexico.


RESULTS
The mean age at natural menopause was 47.9 ± 3.82 years. The primary initial motive for consultation was a preventive examination (40.3%). Significant differences (p values by ANOVA) were observed for the mean total and subscale MRS scores, with the exception of urogenital symptoms, between women in the sub-samples from different Mexican regions. The highest mean MRS total scores were observed for women living in the South (9.08 ± 8.20) and the Center-East (8.55 ± 6.74) regions. The national mean MRS total score was 8.19 ± 6.82. An MRS total score ≥ 17, which is considered severe, was observed for 5.2% of women with a regular cycle, 10.5% with more than 7 days of irregularity, 22.6% with more than two absent cycles, 13.1% that had undergone natural menopause, 16% with a hysterectomy, and 21.2% with a bilateral oophorectomy. The five most frequently reported symptoms were: physical and mental exhaustion (61%), irritability (54.2%), depressive mood (54.2%), sleeping problems (53.3%), joint and muscular discomfort (52.8%).


CONCLUSIONS
Differences in the prevalence and severity of MRS symptoms were observed for women from different Mexican regions. MRS symptoms were more frequent and severe in women who had undergone a bilateral oophorectomy or with more than two absent cycles.
Research Committee of AMEC, Mexico City, Mexico.
D
D
Legorreta
J A
JA
Montaño
I
I
Hernández
C
C
Salinas
J A
JA
Hernández-Bueno
D000328:Adult; D000367:Age Factors; D003430:Cross-Sectional Studies; D003866:Depressive Disorder; D015914:Estrogen Replacement Therapy; D005221:Fatigue; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007508:Irritable Mood; D008593:Menopause / Q000502:physiology*; D008800:Mexico; D008875:Middle Aged; D010052:Ovariectomy; D012017:Referral and Consultation; D012720:Severity of Illness Index; D012893:Sleep Wake Disorders; D011795:Surveys and Questionnaires