[Prostatitis and fertility: the biologist's point of view].
There are two leukocytospermia: the leukocytospermia below 10(6) cells/ml comes from the epididymis. It is physiological, improves sperm quality and ART outcomes and therefore must be respected. Leukocytospermia above 10(6) cells/ml are of prostatic origin and reflect a chronic prostatitis. The results of IVF and ICSI with these sperm are always surprisingly improved when compared to those obtained using semen without leukocytes at all. But this improvement is offset by a dramatic increase in the miscarriage rate. Should we treat this leukocytospermia or its cause? A clinical trial is conducted in Cochin hospital with the PHRC Sigma (Male Genital Track Inflammatory Syndrome) that will help us answer this question. It seems, a priori, that it is better to treat the cause and to respect the leukospermia.
Service d'histologie embryologie-biologie de la reproduction, hôpital Cochin, AP-HP, 123, boulevard Port-Royal, 75014 Paris, France.
N
N
Le Foll
J-C
JC
Pont
J-P
JP
Wolf
A
A
Ziyyat
J-C
JC
Juillard
V
V
Barraud-Lange
D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007239:Infections / Q000150:complications; D007246:Infertility / Q000209:etiology* / Q000473:pathology; D007958:Leukocyte Count; D007962:Leukocytes / Q000473:pathology; D008297:Male; D011247:Pregnancy; D011472:Prostatitis / Q000150:complications* / Q000473:pathology; D012661:Semen / Q000166:cytology; D020554:Sperm Injections, Intracytoplasmic; D013094:Spermatozoa / Q000502:physiology