Synthesis, conformation and vibrational dynamics of the peptide -Ser-Cys-Lys-Leu-Asp-Phe-, a fragment of apolipoprotein B.
The collective normal modes of the hexapeptide -Ser-Cys-Lys-Leu-Asp-Phe-, a fragment of apolipoprotein B (apo B), have been obtained. They reflect the dynamic nature and are atleast partly responsible for energy input in autolytic activity. Further, on energetic considerations based on the measurements reported by Sim & Sim, it has been shown that of the two such fragments only one induces autolysis, while the other remains anchored to the coated pit.
Division of Physiology, Central Drug Research Institue, Lucknow 226 001, India.
Shinoo
S
Srivastava
Seema
S
Srivastava
Girish Chandra
GC
Melkani
Shyam
S
Singh
Vishwambhar Dayal
VD
Gupta
Gupta
G
Vijai Prakash
D000577:Amides / Q000737:chemistry; D000818:Animals; D001055:Apolipoproteins B / Q000737:chemistry*; D001329:Autolysis; D004220:Disulfides / Q000737:chemistry; D006801:Humans; D008956:Models, Chemical; D008968:Molecular Conformation; D010446:Peptide Fragments / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D011487:Protein Conformation; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods
D000577:Amides; D001055:Apolipoproteins B; D004220:Disulfides; D010446:Peptide Fragments; D010455:Peptides