Copper-catalyzed synthesis of purine-fused polycyclics.
A novel protocol for a Cu-catalyzed direct C((sp(2)))-H activation/intramolecular amination reaction of 6-anilinopurine nucleosides has been developed. This approach provides a new access to a variety of multiheterocyclic compounds from purine compounds via Cu-catalyzed intramolecular N-H bond tautomerism which are endowed with fluorescence.
College of Chemistry and Environmental Science, Henan Normal University, Xinxiang 453007, Henan, China.
Gui-Rong
GR
Qu
Lei
L
Liang
Hong-Ying
HY
Niu
Wei-Hao
WH
Rao
Hai-Ming
HM
Guo
John S
JS
Fossey
D000586:Amination; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure; D011687:Purines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
D011687:Purines; D003300:Copper