Highly luminescent biocompatible Carbon Quantum Dots by encapsulation with an amphiphilic polymer.
Highly luminescent, water-soluble and biocompatible Carbon Quantum Dots (aqCQDs) were prepared by encapsulating the parent hydrophobic CQDs in an amphiphilic polymer. The resulting aqCQDs were non-toxic to living cells, and were found to cross the cell membrane and localise primarily in the cytosol.
Department of Pharmacy and Pharmaceutical Sciences, School of Biomedical Sciences, The University of Ulster, Northern Ireland, BT52 1SA, UK.
Colin
C
Fowley
Bridgeen
B
McCaughan
Andrea
A
Devlin
Ibrahim
I
Yildiz
Françisco M
FM
Raymo
John F
JF
Callan
D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000633:toxicity; D016466:CHO Cells; D002214:Capsules; D002244:Carbon / Q000737:chemistry*; D002470:Cell Survival / Q000187:drug effects; D006224:Cricetinae; D003412:Cricetulus; D057927:Hydrophobic and Hydrophilic Interactions; D049408:Luminescent Agents / Q000737:chemistry* / Q000633:toxicity; D011108:Polymers / Q000737:chemistry*; D045663:Quantum Dots
D001672:Biocompatible Materials; D002214:Capsules; D049408:Luminescent Agents; D011108:Polymers; D002244:Carbon