WHO recommendations for the viruses to be used in the 2012 Southern Hemisphere Influenza Vaccine: epidemiology, antigenic and genetic characteristics of influenza A(H1N1)pdm09, A(H3N2) and B influenza viruses collected from February to September 2011.
In February and September each year the World Health Organisation (WHO) recommends influenza viruses to be included in influenza vaccines for the forthcoming winters in the Northern and Southern Hemispheres respectively. These recommendations are based on data collected by National Influenza Centres (NIC) through the Global Influenza Surveillance and Response System (GISRS) and a more detailed analysis of representative and potential antigenically variant influenza viruses from the WHO Collaborating Centres for Influenza (WHO CCs) and Essential Regulatory Laboratories (ERLs). This article provides a detailed summary of the antigenic and genetic properties of viruses and additional background data used by WHO experts during development of the recommendations for the 2012 Southern Hemisphere influenza vaccine composition.
WHO Collaborating Centre for Surveillance, Epidemiology and Control of Influenza, Influenza Division, Centres for Disease Control and Prevention, NE, Atlanta, GA 30333, USA. AKlimov@cdc.gov
Alexander I
AI
Klimov
Rebecca
R
Garten
Colin
C
Russell
Ian G
IG
Barr
Terry G
TG
Besselaar
Rod
R
Daniels
Othmar G
OG
Engelhardt
Gary
G
Grohmann
Shigeyuki
S
Itamura
Anne
A
Kelso
John
J
McCauley
Takato
T
Odagiri
Derek
D
Smith
Masato
M
Tashiro
Xiyan
X
Xu
Richard
R
Webby
Dayan
D
Wang
Zhiping
Z
Ye
Shu
S
Yuelong
Wenqing
W
Zhang
Nancy
N
Cox
D000940:Antigenic Variation; D003429:Cross Reactions; D024882:Drug Resistance, Viral; D014943:Global Health; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000235:genetics / Q000276:immunology; D053122:Influenza A Virus, H3N2 Subtype / Q000235:genetics / Q000276:immunology; D007252:Influenza Vaccines / Q000494:pharmacology*; D007251:Influenza, Human / Q000453:epidemiology / Q000517:prevention & control*; D029524:Betainfluenzavirus / Q000235:genetics / Q000276:immunology; D010802:Phylogeny; D014944:World Health Organization
D007252:Influenza Vaccines