[Study progress on mefloquine against schistosomes and other helminths].
In recent years, antimalarial drug mefloquine, an amino alcohol compound, has been found to exhibit potential effect against schistosomes. The feature of antischistosomal properties of mefloquine is that the drug possesses similar killing effect against various development stages of juvenile and adult schistosomes. This paper summarizes the recent three years' progress in experimental studies of mefloquine against schistosomes and other helminthes.
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China.
Shu-Hua
SH
Xiao
Jian
J
Xue
D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology*; D006376:Helminths / Q000187:drug effects*; D015767:Mefloquine / Q000494:pharmacology*; D012547:Schistosoma / Q000187:drug effects*
D000871:Anthelmintics; D015767:Mefloquine