Juxtarenal Wilms tumor in an adolescent.
A 17-year-old boy presented for evaluation of an abdominal mass. Imaging revealed a 12.5-cm left upper pole renal mass. Biopsy demonstrated a malignant neoplasm consistent with blastemal-type Wilms tumor. The patient received neoadjuvant chemotherapy followed by laparoscopic radical nephrectomy. Examination revealed an unremarkable kidney uninvolved by tumor abutted by a 7.3 cm encapsulated mass. Histology revealed a triphasic Wilms tumor (nephroblastoma) with favorable histology. This tumor was classified as a juxtarenal Wilms tumor, a rare form of extrarenal Wilms tumor, with only 7 cases described in the literature. We present the first case of a juxtarenal Wilms tumor described in an adolescent.
Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, NY 14642-8656, USA. Jennifer_Gordetsky@urmc.rochester.edu
Jennifer
J
Gordetsky
Philip
P
Katzman
Hani
H
Rashid
D000293:Adolescent; D017024:Chemotherapy, Adjuvant; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000628:therapy; D008297:Male; D020360:Neoadjuvant Therapy; D009392:Nephrectomy; D009396:Wilms Tumor / Q000473:pathology* / Q000628:therapy