[New aspects in age related macular degeneration].
Being the leading cause of blindness in modern world Age Related Macular Degeneration has beneficiated in the last decade of important progress in diagnosis, classification and the discovery of diverse factors who contribute to the etiology of this disease. Treatments have arised who can postpone the irreversible evolution of the disease and thus preserve vision. Recent findings have identified predisposing genetic factors and also inflamatory and imunological parameters that can be modified trough a good and adequate prevention and therapy This articole reviews new aspects of patology of Age Related Macular Degeneration like the role of complement in maintaining inflamation and the role of oxidative stress on different structures of the retina.
Clinica de Oftalmologie Timisoara.
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D000368:Aged; D000375:Aging; D001766:Blindness / Q000209:etiology; D003167:Complement Activation / Q000276:immunology; D018450:Disease Progression; D019317:Evidence-Based Medicine; D020022:Genetic Predisposition to Disease; D006801:Humans; D015994:Incidence; D008268:Macular Degeneration / Q000145:classification / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics / Q000276:immunology / Q000628:therapy; D018384:Oxidative Stress; D015995:Prevalence; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology