Preparation of multifunctional nanoparticles and their assemblies.
This article describes the synthesis of multifunctional nanoparticulate systems and a range of organic reactions for modifying the surface functionalities of these particles and their composites. The reactions include surface silanization, amine-azide conversion, azide-alkyne 'click' chemistry, thiol and amine click chemistry and amide coupling. In addition, we discuss a number of relevant nanoparticle preparations to exemplify the interrelationship of these reactions. This system can readily be adapted to produce a wide range of composites with different features, such as fluorescence, magnetism, plasmon resonance and multiple biofunctionalities.
School of Chemistry and CRANN Institute, Trinity College Dublin, Dublin, Ireland.
Sarah A
SA
McCarthy
Gemma-Louise
GL
Davies
Yurii K
YK
Gun'ko
D000577:Amides / Q000737:chemistry*; D053000:Analytic Sample Preparation Methods / Q000379:methods*; D001386:Azides / Q000737:chemistry*; D005453:Fluorescence; D008280:Magnetics; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology / Q000379:methods*; D012821:Silanes / Q000737:chemistry*; D020349:Surface Plasmon Resonance; D013499:Surface Properties
D000577:Amides; D001386:Azides; D058185:Magnetite Nanoparticles; D012821:Silanes