[Detection of Crimean-Congo hemorrhagic fever virus RNA in the hyalomma marginatum ticks taken from bitten people].
Among 1076 imagoes of the Hyalomma marginatum ticks taken from bitten people in the Astrakhan Region in 2006-2010, 10 (0.9%) ticks contained Crimean-Congo hemorrhagic fever (CCHF) virus RNA, as evidenced by RT-PCR. The diagnosis of CCHF was made on the basis of clinical data and the results of examination of sera in RT-PCR, ELISA-IgM, and ELISA-IgA in three of the 10 persons bitten by infected ticks. Two more patients were observed to have acute febrile diseases, but their sera were not examined in RT-PCR and ELISA, so their etiological association with CCHF virus RNA was not reliably established.
D000328:Adult; D000368:Aged; D000818:Animals; D001733:Bites and Stings; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D003225:Hemorrhagic Fever Virus, Crimean-Congo / Q000302:isolation & purification*; D006479:Hemorrhagic Fever, Crimean / Q000097:blood / Q000175:diagnosis / Q000821:virology; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D012367:RNA, Viral / Q000302:isolation & purification*; D013987:Ticks / Q000821:virology*
D007070:Immunoglobulin A; D007075:Immunoglobulin M; D012367:RNA, Viral