[Risk factors of left ventricular diastolic dysfunction in patients with coronary heart disease].
The last decade has witnessed increased interest in the problem of left ventricular diastolic dysfunction (LVDD) due to the growing prevalence of this condition (25-30% in patients above 45 years of age). In view of difficulties encountered in diagnostics of LVDD, we undertook the search for a continuum of concomitant pathology and predisposing factors in patients with coronary heart disease (CHD) based on the clinical data, results of one- and two-dimensional echocardiography, pulsed- and continuous-wave Doppler echocardiography, Doppler tissue visualization (DTV), and ultrasonic mapping of elastic-type arteries. The study included 119 patients with CHD and 2.69+-9. 46 functional class (nYHA) cardiac failure. Control group was comprised of 162 CHD patients without cardiac failure. LVDD was regarded as a dichotomic problem: 0 - the absence of the disease or LVDD. 1 - the presence of the disease or LVDD. The data obtained were treated by single- or multifactor analysis. Calculations using the relevant equation allowed the risk of LVDD in the studied cohort to be estimated with sensitivity 92.0% and specificity 91.2%.
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Khamuev
D000368:Aged; D002339:Carotid Arteries / Q000000981:diagnostic imaging* / Q000473:pathology; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D004452:Echocardiography; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors; D012720:Severity of Illness Index; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000503:physiopathology