Quantitative ultrasound measurement of intima-media thickness of abdominal aorta and common carotid arteries in normal term newborns.
The objective of this study was to measure intima-media thickness (IMT) of the abdominal aortic (aIMT) and common carotid (cIMT) arteries in normal term newborns. We measured aIMT and cIMT using high-resolution ultrasonography in 100 normal term newborns during the first 4 days of life. Mean abdominal aIMT and cIMT values of term newborns were 0.51 ± 0.041 mm (n = 100) and 0.37 ± 0.054 mm (n = 100), respectively. Maximum and minimum aIMT and cIMT values of term newborns were 0.58 and 0.42 mm and 0.47 and 0.32 mm, respectively. The intraobserver intrasubject correlation coefficients for aIMT, right cIMT, and left cIMT were 0.89, 0.91, and 0.92, respectively (coefficient of variation = 5 %). The study provides data for normal aIMT and cIMT values in normal term newborns. By establishing normal values, we can further study the aetiopathogenesis of various possible intrauterine risk factors in premature atherosclerosis in normal or intrauterine growth-retarded newborns.
Department of Radiodiagnosis, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India.
Anil
A
Hondappanavar
Kushaljit Singh
KS
Sodhi
Sourabh
S
Dutta
Akshay Kumar
AK
Saxena
Niranjan
N
Khandelwal
D001012:Aorta, Abdominal / Q000000981:diagnostic imaging*; D050197:Atherosclerosis / Q000000981:diagnostic imaging; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging*; D059168:Carotid Intima-Media Thickness; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007231:Infant, Newborn; D008297:Male; D012372:ROC Curve; D012016:Reference Values