Comparative modelling of tetramanganese cluster of Chaetosphaeridium globosum.
The DI protein of photosystem II (PS II) complex of a microalga Chaetosphaeridium globosum has been theoretically modelled from its sequence using comparative modeling with known backbone structure of DI protein from bacterium Thermosynechococcus vulcanus as template. The model is built with missing loops and all side chains, which are not resolved in the structure of the template. The structure of the tetramanganese cluster (TMC) and the ligand forming side chains have been subjected to modeling studies in order to gather more information useful to understanding of the water splitting reactions. Earlier models of TMC have been scrutinized and an insight into the manganese coordination sphere has been provided.
Bioinformatics Research Center, International Institute of Information Technology, Gachibowli, Hyderabad-500 019, India.
L S
LS
Rath
M K
MK
Raval
D000595:Amino Acid Sequence; D002118:Calcium / Q000737:chemistry; D018360:Crystallography, X-Ray / Q000379:methods; D000458:Cyanobacteria / Q000378:metabolism; D008024:Ligands; D008345:Manganese / Q000737:chemistry*; D008958:Models, Molecular; D008962:Models, Theoretical; D008968:Molecular Conformation; D008969:Molecular Sequence Data; D010100:Oxygen / Q000737:chemistry; D045332:Photosystem II Protein Complex; D011485:Protein Binding; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D017386:Sequence Homology, Amino Acid; D057949:Streptophyta / Q000201:enzymology*; D014867:Water / Q000737:chemistry
D008024:Ligands; D045332:Photosystem II Protein Complex; D014867:Water; D008345:Manganese; D010100:Oxygen; D002118:Calcium