Hyperbilirubinemic stain: location and extent in dental tissues.
OBJECTIVE
The purpose of the present manuscript is to describe the location and extent of hyperbilirubinemic stain in a primary molar of a 3-year-old who was diagnosed with cystic fibrosis shortly after birth, subsequently developed liver disease and hyperbilirubinemia, and received a liver transplant at age 10-months.


METHODS
Clinical and histological assessments were performed to evaluate the location and extent of hyperbilirubinemic stain in an extracted primary molar.


RESULTS
The clinical image, and macroscopic and microscopic histological examinations of a primary molar showed hyperbilirubinemic staining of enamel and of the coronal dentin that developed between birth and when the liver transplant took place, irregular dentin tubules, and an irregular cementum-dentinal junction.


CONCLUSIONS
The findings of the present manuscript indicate that hyperbilirubinemc staining of primary teeth affects dental hard tissues at the time of their calcification, and the clinical picture of the stain may be related to stained enamel and/or dentin, and underlying stained dentin visible through translucent unstained enamel.
Department of Pediatric Dentistry, College of Dentistry, University of Kentucky, Lexington 40536, USA. ebi883@uky.edu
E
E
Bimstein
K
K
Magliocca
D
D
Cohen
G
G
Morelli
J
J
Katz
D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications* / Q000473:pathology; D003744:Dental Enamel Hypoplasia / Q000209:etiology / Q000473:pathology; D003782:Dental Pulp / Q000473:pathology; D003804:Dentin / Q000002:abnormalities / Q000473:pathology*; D006801:Humans; D051556:Hyperbilirubinemia, Neonatal / Q000150:complications / Q000209:etiology / Q000473:pathology*; D017093:Liver Failure / Q000209:etiology / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D008963:Molar / Q000473:pathology*; D014094:Tooth, Deciduous / Q000473:pathology