[Pestivirus].
Members of the genus Pestivirus, are causative agents of economically important diseases for livestock and wild animals that occur worldwide, such as bovine viral diarrhea, classical swine fever, and border disease of sheep. Pestivirus have novel insertions of host genes in the viral genome and functions of unique viral proteins, N(pro) and E(rns), related to the pathogenicity although genomic structure is closely related to the other viruses of Flaviviridae family, especially hepatitis C virus. In this review, recent studies on the molecular basis of pathogenicity of pestivirus infections were summarized.
Laboratory of Microbiology, Graduate School of Veterinary Medicine, Hokkaido University, Kita-18 Nishi-9, Sapporo 060-0818, Japan. influ@vetmed.hokudai.ac.jp
Yoshihiro
Y
Sakoda
D000818:Animals; D002417:Cattle; D016679:Genome, Viral; D006801:Humans; D010576:Pestivirus / Q000235:genetics* / Q000472:pathogenicity*; D018182:Pestivirus Infections / Q000662:veterinary / Q000821:virology*; D010802:Phylogeny; D014764:Viral Proteins / Q000502:physiology
D014764:Viral Proteins