Predictors of success and satisfaction of nonsurgical therapy for stress urinary incontinence.
OBJECTIVE
To identify factors that may predict success and satisfaction in women undergoing nonsurgical therapy for stress urinary incontinence.


METHODS
Baseline demographic and clinical characteristics of women participating in a multicenter randomized trial of pessary, behavioral, or combined therapy for stress urinary incontinence were evaluated for potential predictors of success and satisfaction. Success and satisfaction outcomes were assessed at 3 months and included the Patient Global Impression of Improvement, stress incontinence subscale of the Pelvic Floor Distress Inventory, and Patient Satisfaction Questionnaire. Logistic regression was performed to identify predictors, adjusting for treatment and other important clinical covariates. Adjusted odds ratios (ORs), 95% confidence intervals (CIs), and associated P values are presented.


RESULTS
Four hundred forty-six women were randomized. College education or more and no previous urinary incontinence surgery predicted success based on the stress subscale of the Pelvic Floor Distress Inventory (adjusted OR 1.61, 95% CI 1.01-2.55, P=.04 and adjusted OR 3.15, 95% CI 1.04- 9.53, P=.04, respectively). Menopausal status predicted success using the Patient Global Impression of Improvement (adjusted OR 2.52 postmenopausal compared with premenopausal, 95% CI 1.29-4.95; adjusted OR 1.32 unsure menopausal status compared with premenopausal, 95% CI 0.65-2.66; P=.03 across all three groups). Fewer than 14 incontinence episodes per week predicted satisfaction with the Patient Satisfaction Questionnaire (adjusted OR 1.97, 95% CI 1.21-3.19; P=.01). These predictors did not differ across the three treatment groups.


CONCLUSIONS
Menopause, higher education, no previous urinary incontinence surgery, and lower incontinence frequency were found to be predictors of success and satisfaction with nonsurgical therapy for stress urinary incontinence. This information may help better-align provider and patient expectations with nonsurgical treatment outcomes.
University of Texas Southwestern, Dallas, TX, USA.
Joseph
J
Schaffer
Charles W
CW
Nager
Fang
F
Xiang
Diane
D
Borello-France
Catherine S
CS
Bradley
Jennifer M
JM
Wu
Elizabeth
E
Mueller
Peggy
P
Norton
Marie Fidela R
MF
Paraiso
Halina
H
Zyczynski
Holly E
HE
Richter
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004522:Educational Status; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D017060:Patient Satisfaction / Q000706:statistics & numerical data*; D010570:Pessaries / Q000706:statistics & numerical data; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014550:Urinary Incontinence, Stress / Q000628:therapy*; D055815:Young Adult