Frequency of recurrent spontaneous abortion and its influence on further marital relationship and illness: the Okazaki Cohort Study in Japan.
OBJECTIVE
The aim of this study was to examine the influence of recurrent spontaneous abortion (RSA) on marital relationships, and the association between past/present illness and RSA.


METHODS
A total of 2733 Japanese women who underwent a medical examination responded to the questionnaire.


RESULTS
The frequency of recurrent miscarriage and two or more consecutive RSA were 0.88% and 4.2%, respectively. Women with a history of miscarriages (hazard ratio: 1.596) and RSA (hazard ratio: 3.103) were at a higher risk of their relationships ending as compared with the women without a history of miscarriage. Existence of a relation was seen between a history of RSA and the occurrence of gastric ulcer, gastritis, fatty liver, and atopic dermatitis. Overall, 89.5% of the women with RSA experienced cumulative live births.


CONCLUSIONS
Miscarriage was found to be a severe life event with an influence on marital relationships, and to be associated with an elevated risk of gastric disease or atopic dermatitis.
Departments of Obstetrics and Gynecology             Public Health, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Mayumi
M
Sugiura-Ogasawara
Sadao
S
Suzuki
Yasuhiko
Y
Ozaki
Kinue
K
Katano
Nobuhiro
N
Suzumori
Tamao
T
Kitaori
D000026:Abortion, Habitual / Q000453:epidemiology* / Q000523:psychology*; D000328:Adult; D015331:Cohort Studies; D005260:Female; D006304:Health Status; D006801:Humans; D007564:Japan; D008016:Life Change Events; D008393:Marriage / Q000523:psychology*; D011247:Pregnancy