Clostridium celerecrescens, often misidentified as "Clostridium clostridioforme group," is involved in rare human infection cases.
Misidentification of rare Clostridium species often originated from the environment as clinically relevant species is problematic. A strain isolated from a traumatic leg wound first identified as C. clostridioforme was finally identified as the rare Clostridium celerecrescens. Two similar misidentifications are reported in the literature. In order to help the phenotypic differentiation of C. celerecrescens from the close species of the "C. clostridioforme group", an identification table and differential susceptibilities to 4 selected antibiotics are proposed. Once a clinical isolate is referred to this group, identification should be definitively confirmed by unambiguous methods such as 16s rDNA sequencing.
Institut Pasteur, Centre National de Référence des Bactéries Anaérobies et du Botulisme, Unité Bactéries anaérobies et Toxines, 25-28 rue du Docteur Roux, F-75724 Paris cedex 15, France. philippe.bouvet@pasteur.fr
Philippe
P
Bouvet
Guylène
G
K'Ouas
Alain
A
Le Coustumier
Michel R
MR
Popoff
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015373:Bacterial Typing Techniques; D003013:Clostridium / Q000145:classification / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity*; D003015:Clostridium Infections / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D014946:Wound Infection / Q000382:microbiology* / Q000473:pathology*; D014947:Wounds and Injuries / Q000150:complications; D055815:Young Adult
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S