Managing apheresis complications during the hematopoietic stem cell collection.
Adverse reactions may occur during the Hematopoietic Progenitor Cells via Apheresis (HPC-A) -collection, although they are rare. They can be associated with physical, psychological, or environmental factors. The most common complications are hypocalcemia related to citrate toxicity, allergic reactions, and vasovagal reactions. Recognizing and treating the symptom early can reduce the severity of most of these reactions. Procedural steps are outlined in this chapter for the proper management of apheresis complications.
Center for Transfusion and Cellular Therapies, Emory University Hospital, Atlanta, GA, USA. darlene.marlow@emoryhealthcare.org
S Darlene
SD
Marlow
Myra
M
House
D001781:Blood Component Removal / Q000009:adverse effects*; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D006996:Hypocalcemia / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*; D007937:Leukapheresis; D019462:Syncope, Vasovagal / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*