Systemic amyloidosis complicating multidrug-resistant tuberculosis in childhood.
Multidrug-resistant tuberculosis is increasingly common and is associated with long diagnostic delay and high morbidity. We present a 7-year-old child who developed steroid-resistant nephrotic syndrome while receiving treatment for tuberculosis. Renal biopsy results showed systemic amyloidosis; culture of peritoneal tissue confirmed disseminated multidrug-resistant tuberculosis.
Paediatric Infectious Disease Unit, University of Cape Town, Cape Town, South Africa. drdaveleroux@ gmail.com
David M
DM
le Roux
Komala
K
Pillay
Peter
P
Nourse
Priya
P
Gajjar
James J
JJ
Nuttall
Brian S
BS
Eley
D000686:Amyloidosis / Q000175:diagnosis / Q000382:microbiology*; D000995:Antitubercular Agents / Q000627:therapeutic use; D002648:Child; D006801:Humans; D008297:Male; D013019:South Africa; D018088:Tuberculosis, Multidrug-Resistant / Q000150:complications* / Q000188:drug therapy
D000995:Antitubercular Agents