title: Bcl-2: Live and let die.
abstract: Recent findings from our laboratory provide the first indication that overexpression of Bcl-2 in Eµ-myc transgenic cells enhances tumor immunosurveillance by inducing NKG2D ligands. Initial evidence suggests that this model is relevant to human patients. Thus, antitumor therapies that target Bcl-2 harbor the risk of reducing tumor immunogenicity.
authors.affiliation: Institute of Pharmacology and Toxicology; Department for Biomedical Sciences; Veterinary University of Vienna; Vienna, Austria.
authors.forename: Eva Maria
authors.initials: EM
authors.lastname: Putz
authors.forename: Christian
authors.initials: C
authors.lastname: Schuster
authors.forename: Veronika
authors.initials: V
authors.lastname: Sexl