title: Widespread atypical vascular lesions of the skin after whole-body electron beam therapy:  expanding the clinical spectrum.
abstract: Atypical vascular lesion of the skin is an uncommon usually benign condition, thus far reported almost exclusively from mammary skin after radiotherapy for carcinoma of the breast. Some clinical and histological overlap exists with early angiosarcoma, which can also occur on irradiated skin. The lesions are divided into vascular and lymphatic types, the first representing a higher risk for development of angiosarcoma and the latter being more common. This article reports a rare case of widespread, progressive, vascular-type atypical vascular lesion after repeated whole-body electron beam irradiation administered as treatment for mycosis fungoides.
authors.affiliation: Department of Dermatology, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa. sinclairw@ufs.ac.za
authors.forename: Werner
authors.initials: W
authors.lastname: Sinclair
mesh_terms: D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000532:radiotherapy*; D009336:Necrosis; D011832:Radiation Injuries / Q000209:etiology* / Q000473:pathology; D012867:Skin / Q000098:blood supply* / Q000473:pathology / Q000528:radiation effects*; D017445:Skin Diseases, Vascular / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D012883:Skin Ulcer / Q000209:etiology / Q000473:pathology; D013684:Telangiectasis / Q000209:etiology / Q000473:pathology; D014916:Whole-Body Irradiation / Q000009:adverse effects*
chemical_list: D015415:Biomarkers