title: Regulating intraflagellar transport.
abstract: Kinesin-2 motors mediate anterograde intraflagellar transport (IFT) of IFT particles from the ciliary base to its tip, where particles are remodelled before retrograde transport by dynein 2 motors. Bardet-Biedl syndrome (BBS) and IFT-A proteins are now implicated in regulation of IFT assembly at the ciliary base and tip.
authors.affiliation: Department of Biology, University of Copenhagen, Universitetsparken 13, DK-2100 Copenhagen, Denmark. lbpedersen@bio.ku.dk
authors.forename: Lotte B
authors.initials: LB
authors.lastname: Pedersen
authors.forename: Søren T
authors.initials: ST
authors.lastname: Christensen
mesh_terms: D000818:Animals; D020788:Bardet-Biedl Syndrome / Q000378:metabolism*; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism*; D002923:Cilia / Q000378:metabolism*; D005407:Flagella / Q000378:metabolism*; D006801:Humans
chemical_list: D029742:Caenorhabditis elegans Proteins