title: Metal carbonyl-gold nanoparticle conjugates for live-cell SERS imaging.
abstract: Conjugates of organometallic osmium carbonyl clusters and gold nanoparticles show a strong carbonyl signal in surface-enhanced Raman spectroscopy. The ease of bio-functionalization and the high stability and good dispersibility in aqueous solution make these conjugates excellent candidates for biomedical applications, as demonstrated by live-cell imaging with the carbonyl signals of OM-NP(PEG)-L conjugates.
authors.affiliation: Singapore Bioimaging Consortium, Agency for Science, Technology, and Research (A*STAR), 138667 Singapore, Singapore.
authors.forename: Kien Voon
authors.initials: KV
authors.lastname: Kong
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Lam
authors.forename: Wenda Douglas
authors.initials: WD
authors.lastname: Goh
authors.forename: Weng Kee
authors.initials: WK
authors.lastname: Leong
authors.forename: Malini
authors.initials: M
authors.lastname: Olivo
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000175:diagnosis*; D045744:Cell Line, Tumor; D002470:Cell Survival; D006046:Gold / Q000737:chemistry; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry / Q000648:ultrastructure; D013059:Spectrum Analysis, Raman / Q000379:methods*
chemical_list: D006046:Gold