title: The genetic factors influencing the development of trichotillomania.
abstract: Trichotillomania (TTM), an obsessive-compulsive spectrum disorder (OCSD), is a psychiatric condition characterized by repetitive hair pulling. Evidence from family and twin studies suggest a heritable link of TTM. Functional polymorphisms in genes involved in neuronal pathways might influence the susceptibility to TTM. This review is an attempt to compile the genetic factors reported to modify the development of TTM.
authors.affiliation: Nelson R. Mandela School of Medicine, University of Kwazulu-Natal, Durban, Republic of South Africa. chatt_k@yahoo.com [corrected].
authors.forename: Koushik
authors.initials: K
authors.lastname: Chattopadhyay
authors.forename: Koushik
authors.initials: K
authors.lastname: Chatterjee
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology / Q000627:therapeutic use; D056726:Genetic Association Studies; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics; D009419:Nerve Tissue Proteins / Q000235:genetics; D044402:Receptor, Serotonin, 5-HT2A / Q000235:genetics; D011954:Receptors, Dopamine / Q000235:genetics; D000074407:SAP90-PSD95 Associated Proteins; D050486:Serotonin Plasma Membrane Transport Proteins / Q000235:genetics; D017367:Selective Serotonin Reuptake Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D015398:Signal Transduction / Q000235:genetics; D014256:Trichotillomania / Q000188:drug therapy / Q000235:genetics*; D018433:Twin Studies as Topic
chemical_list: D000928:Antidepressive Agents; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; D044402:Receptor, Serotonin, 5-HT2A; D011954:Receptors, Dopamine; D000074407:SAP90-PSD95 Associated Proteins; D050486:Serotonin Plasma Membrane Transport Proteins; D017367:Selective Serotonin Reuptake Inhibitors; C505093:SLITRK1 protein, human