title: Malignant Range Elevation of Serum Chromogranin A due to Inadvertent Use of Proton Pump Inhibitor in a Subject with Pancreatic Incidentaloma.
abstract: We present a case of highly elevated tenfold rise of serum chromogranin A in a young, morbidly obese, hypertensive female being investigated for pancreatic mass, weight loss, and elevated ESR. Following extensive noninvasive investigations, an ultrasound-guided pancreatic biopsy confirmed benign haemorrhagic cyst. A clue to the etiology of the hyperchromogranin A was the elevated serum gastrin level leading to suspicion of proton pump inhibitor administration confirmed by admittance to its use. Withdrawal of the medication led to dramatic resolution of the neuroendocrine tumor marker.
authors.affiliation: Department of Endocrinology, Townsville Hospital, 100 Angus Smith Drive, Douglas QLD 4814, Australia.
authors.forename: Usman Hammawa
authors.initials: UH
authors.lastname: Malabu
authors.forename: Rozemary
authors.initials: R
authors.lastname: Karamatic
authors.forename: Gillian
authors.initials: G
authors.lastname: Mahy
authors.forename: Kunwarjit Singh
authors.initials: KS
authors.lastname: Sangla