title: [The value of Doppler echocardiography in assessment of pulmonary capillary wedge pressure in pulmonary hypertension].
abstract: OBJECTIVE
  To explore the association between Doppler echocardiography parameters and pulmonary capillary wedge pressure (PCWP) obtained by right heart catheterization (RHC) in patients with pulmonary hypertension (PH).
  
  
  METHODS
  RHC and a simultaneous echocardiography were performed in 86 PH patients. The correlation between the echocardiographic parameters and PCWP was analyzed.
  
  
  RESULTS
  The early diastolic velocity (E) of mitral valve blood flow was significantly correlated with PCWP (r = 0.36, P < 0.01). Tissue Doppler imaging measured the diastolic velocity of mitral annulus on the lateral (E'L) and the septal (E'S) wall. Then the average E'M was calculated. The ratio of E to E'L, E'S and E'M showed a strong correlation with PCWP (r = 0.62, 0.34 and 0.47 respectively, P < 0.01). E/E'L < 6 accurately predicted 100% PCWP ≤ 15 mm Hg (1 mm Hg = 0.133 kPa), and E/E'L > 15 could predict PCWP > 15 mm Hg with specificity of 98.5%.
  
  
  CONCLUSIONS
  There are positive correlation between E/E' and PCWP obtained by RHC in PH patients.
authors.affiliation: Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
authors.forename: Zhuang
authors.initials: Z
authors.lastname: Tian
authors.forename: Xiao-xiao
authors.initials: XX
authors.lastname: Guo
authors.forename: Yong-tai
authors.initials: YT
authors.lastname: Liu
authors.forename: Meng-tao
authors.initials: MT
authors.lastname: Li
authors.forename: Xiao-feng
authors.initials: XF
authors.lastname: Zeng
authors.forename: Quan
authors.initials: Q
authors.lastname: Fang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D006328:Cardiac Catheterization; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging; D011446:Prospective Studies; D011669:Pulmonary Wedge Pressure; D055815:Young Adult