title: Pulmonary extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue associated with granulomatous inflammation in a child with chromosome 22q11.2 deletion syndrome (DiGeorge syndrome).
abstract: Patients with immunodeficiency disorders have an increased incidence of lymphoproliferative disorders; however, only 4 such patients with DiGeorge/chromosome 22q11.2 deletion syndrome have been reported. We report a case of a pulmonary Epstein-Barr virus-negative extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in a child with this syndrome.
authors.affiliation: Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
authors.forename: Tawatchai
authors.initials: T
authors.lastname: Pongpruttipan
authors.forename: James R
authors.initials: JR
authors.lastname: Cook
authors.forename: Miguel
authors.initials: M
authors.lastname: Reyes-Mugica
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Spahr
authors.forename: Steven H
authors.initials: SH
authors.lastname: Swerdlow
mesh_terms: D000293:Adolescent; D002892:Chromosomes, Human, Pair 22 / Q000235:genetics; D015897:Comorbidity; D004062:DiGeorge Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D017353:Gene Deletion; D006099:Granuloma / Q000378:metabolism; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007249:Inflammation / Q000378:metabolism*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D055613:Multiple Pulmonary Nodules / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D014057:Tomography, X-Ray Computed / Q000379:methods