title: Effects of methionine hydroxy copper supplementation on lactation performance, nutrient digestibility, and blood biochemical parameters in lactating cows.
abstract: The objective of this study was to investigate the effects of methionine hydroxy Cu [(HMTBA)(2)-Cu] supplementation on lactation performance, nutrient digestibility, and blood biochemical parameters in lactating cows. Thirty lactating Holstein cows were assigned to 1 of 3 treatments in a randomized block design: (1) Cu sulfate only (S): 12 mg of Cu provided by CuSO(4) per kilogram of concentrate; (2) Cu sulfate and (HMTBA)(2)-Cu (SM): 6 mg of Cu provided by CuSO(4) and 6 mg of Cu provided by (HMTBA)(2)-Cu per kilogram of concentrate; or (3) (HMTBA)(2)-Cu only (M): 12 mg of Cu provided by (HMTBA)(2)-Cu per kilogram of concentrate. The level of dietary Cu was determined according to the NRC (2001) requirement. This experiment lasted for 120 d, with the first 20 d for adaptation and with sample and data collection beginning on d 21. The milk yield and 4% fat-corrected milk yield of cows in the SM treatment tended to increase compared with those in the S and M treatments. Cows fed SM also tended to have higher NDF and ADF apparent digestibility values than did cows fed S or M. Plasma Cu concentration significantly increased for the SM treatment compared with the S and M treatments. Cows fed S had higher plasma K concentration than did cows in the other 2 treatments. In conclusion, replacing one-half of the dietary Cu sulfate with (HMTBA)(2)-Cu increased plasma Cu concentration and tended to improve the neutral and acid detergent fiber apparent digestibility values and the lactation performance of lactating dairy cattle.
authors.affiliation: State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing 100193, P. R. China.
authors.forename: F
authors.initials: F
authors.lastname: Wang
authors.forename: S L
authors.initials: SL
authors.lastname: Li
authors.forename: J
authors.initials: J
authors.lastname: Xin
authors.forename: Y J
authors.initials: YJ
authors.lastname: Wang
authors.forename: Z J
authors.initials: ZJ
authors.lastname: Cao
authors.forename: F C
authors.initials: FC
authors.lastname: Guo
authors.forename: Y M
authors.initials: YM
authors.lastname: Wang
mesh_terms: D000824:Animal Nutritional Physiological Phenomena / Q000187:drug effects / Q000502:physiology; D000818:Animals; D001798:Blood Proteins / Q000032:analysis; D001806:Blood Urea Nitrogen; D002417:Cattle / Q000097:blood / Q000502:physiology; D003300:Copper / Q000097:blood / Q000494:pharmacology*; D019327:Copper Sulfate / Q000494:pharmacology; D019587:Dietary Supplements; D004063:Digestion / Q000187:drug effects* / Q000502:physiology; D005260:Female; D007774:Lactation / Q000187:drug effects* / Q000502:physiology; D007785:Lactose / Q000032:analysis; D008715:Methionine / Q000494:pharmacology; D008894:Milk Proteins / Q000032:analysis; D011188:Potassium / Q000097:blood
chemical_list: D001798:Blood Proteins; D008894:Milk Proteins; D003300:Copper; D008715:Methionine; D007785:Lactose; D019327:Copper Sulfate; D011188:Potassium