title: Evaluating safer conception options for HIV-serodiscordant couples (HIV-infected female/HIV-uninfected male): a closer look at vaginal insemination.
abstract: HIV serodiscordant couples represent at least half of all HIV-affected couples worldwide. Many of these couples have childbearing desires. Safer methods of conception may allow for pregnancy while minimizing the risk of sexual transmission of HIV. In serodiscordant partnerships with an HIV-infected female and HIV-uninfected male, vaginal insemination of a partner's semen during the fertile period coupled with 100% condom use may be the safest method of conception.
authors.affiliation: Department of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, San Francisco, CA 94110, USA. mmejeo@globalhealth.ucsf.edu
authors.forename: Okeoma
authors.initials: O
authors.lastname: Mmeje
authors.forename: Craig R
authors.initials: CR
authors.lastname: Cohen
authors.forename: Deborah
authors.initials: D
authors.lastname: Cohan
mesh_terms: D017280:Condoms; D018562:Disease Transmission, Infectious / Q000517:prevention & control*; D005260:Female; D005306:Fertilization; D015658:HIV Infections / Q000517:prevention & control* / Q000635:transmission*; D006801:Humans; D007315:Insemination, Artificial / Q000379:methods*; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control*; D012307:Risk Factors; D012747:Sexual Partners