title: Evolution in microfluidic droplet.
abstract: High-throughput screening (HTS) of enzymatic activity is important for directed evolution-based enzyme engineering. However, substrate and product diffusion can severely compromise these HTS assays. In this issue of Chemistry & Biology, Kintses and coworkers describe a microfluidic platform for the directed evolution of enzymes in droplets that allows for the screening of 10(7) mutants per round of evolution.
authors.forename: Itay
authors.initials: I
authors.lastname: Levin
authors.forename: Amir
authors.initials: A
authors.lastname: Aharoni