title: [Progress of researches on involvement of serotonin in the central nervous system in acupuncture analgesia and other effects].
abstract: As for an important central regulatory neurotransmitter involving acupuncture effect, serotonin (5-HT) is worthy of being paid with more attention. In the present paper, the authors review development of researches on the involvement of 5-HT and its receptor subunits in pain perception, acupuncture analgesia, and other effects of acupuncture (anti-depression, weight-reduction, etc.). Many studies showed that acupuncture intervention could modulate the content and activity of central 5-HT, and these changes varied under different conditions. Hence, the relationship between 5-HT and other neurotransmitters in acupuncture analgesia and its different functions in different regions of the central nervous system should be considered comprehensively.
authors.affiliation: Institute of Acu-moxibustion and Meridian, Anhui College of Traditional Chinese Medicine, Hefei 230038, China.
authors.forename: Wu-Bin
authors.initials: WB
authors.lastname: Hu
authors.forename: Zi-Jian
authors.initials: ZJ
authors.lastname: Wu
authors.forename: Ke-Ming
authors.initials: KM
authors.lastname: Wang
mesh_terms: D015667:Acupuncture Analgesia / Q000379:methods*; D000818:Animals; D002490:Central Nervous System / Q000378:metabolism*; D006801:Humans; D010146:Pain / Q000378:metabolism; D059408:Pain Management; D011985:Receptors, Serotonin / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism*
chemical_list: D011985:Receptors, Serotonin; D012701:Serotonin