title: Synthetic approaches and pharmacological activity of 1,3,4-oxadiazoles: a review of the literature from 2000-2012.
abstract: This review provides readers with an overview of the main synthetic methodologies for 1,3,4-oxadiazole derivatives, and of their broad spectrum of pharmacological activities as reported over the past twelve years.
authors.affiliation: Department of Chemistry, Federal University of Paraíba, 58051-900 João Pessoa-PB, Brazil.
authors.forename: Cledualdo Soares
authors.initials: CS
authors.lastname: de Oliveira
authors.forename: Bruno Freitas
authors.initials: BF
authors.lastname: Lira
authors.forename: José Maria
authors.initials: JM
authors.lastname: Barbosa-Filho
authors.forename: Jorge Gonçalo Fernandez
authors.initials: JG
authors.lastname: Lorenzo
authors.forename: Petrônio Filgueiras
authors.initials: PF
authors.lastname: de Athayde-Filho
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D010069:Oxadiazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D011759:Pyrrolidines / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D011760:Pyrrolidinones / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D000068898:Raltegravir Potassium
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000935:Antifungal Agents; D010069:Oxadiazoles; D011759:Pyrrolidines; D011760:Pyrrolidinones; C511404:ZD4054; D000068898:Raltegravir Potassium