title: miRNA-mediated GALNT modulation of invasion and immune suppression: A sweet deal for metastatic cells.
abstract: Glycosylation is a key process impacting on many aspects of cellular interactions. We recently reported that a miRNA cluster controls glycosylation by directly targeting N-acetylgalactosamine transferases (GALNTs), resulting in increased tumor invasion and immunosuppression. Here we further discuss how defective glycosylation or GALNTs dysregulation may contribute to tumor progression.
authors.affiliation: Department of Pathology; New York University School of Medicine; New York, NY USA.
authors.forename: Avital
authors.initials: A
authors.lastname: Gaziel-Sovran
authors.forename: Eva
authors.initials: E
authors.lastname: Hernando