title: Gender-specific high-flexion knee prosthesis in Indian women: a prospective randomised study.
abstract: OBJECTIVE
  To compare outcomes in Indian women who underwent total knee arthroplasty (TKA) using the standard Legacy Posterior Stabilised (LPS) versus the gender-specific LPS high-flexion knee prosthesis.
  
  
  METHODS
  100 women (200 knees) aged 60 to 80 years with an arc of flexion of ≥90º underwent simultaneous sequential TKA for primary osteoarthritis of both knees. They were randomised to receive the standard NexGen LPS prosthesis (n=50) or the gender-specific NexGen LPS High-Flex prosthesis (n=50). Both knees in each patient received the same prosthesis. The resected bone from the posterior femoral condyle was 2 mm greater when the gender-specific prosthesis was used. Patients were followed up at 3, 6, 12, and 24 months. Range of motion, Knee Society score, and Hospital for Special Surgery score were evaluated pre- and post-operatively by a single assessor.
  
  
  RESULTS
  The mean follow-up duration was 2.1 (range, 1.6-2.5) years. Respectively for the standard and gender-specific groups, the mean range of motion was 111º and 112º preoperatively and 120º and 123º at the latest follow-up. The gender-specific group gained approximately 3º more in range of motion (p=0.007). The Knee Society score and the Hospital for Special Surgery score between groups were not significantly different pre- and post-operatively.
  
  
  CONCLUSIONS
  The perceived advantage of a gender-specific prosthesis over a standard prosthesis did not translate into better clinical and functional outcome scores.
authors.affiliation: Department of Orthopaedics, Delhi Institute of Trauma and Orthopaedics, Sant Parmanand Hospital, Delhi, India.
authors.forename: Harjoban
authors.initials: H
authors.lastname: Singh
authors.forename: Vivek
authors.initials: V
authors.lastname: Mittal
authors.forename: Biren
authors.initials: B
authors.lastname: Nadkarni
authors.forename: Shekhar
authors.initials: S
authors.lastname: Agarwal
authors.forename: Divesh
authors.initials: D
authors.lastname: Gulati
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007194:India; D007720:Knee Prosthesis; D008875:Middle Aged; D011446:Prospective Studies; D011474:Prosthesis Design; D016059:Range of Motion, Articular; D012727:Sex Characteristics