title: Evaluation of a completely automated tissue-sectioning machine for paraffin blocks.
abstract: Tissue sectioning automation can be a resourceful tool in processing anatomic pathology specimens. The advantages of an automated system compared with the traditional manual sectioning rely on the consistency of the final sectioned material translated into invariable thickness, uniform orientation during serial sectioning and less tissue sectioning artifacts. This technical note presents the design of an automated tissue-sectioning device and compares the sectioned specimens with normal manual tissue sectioning performed by experienced histology technician.
authors.affiliation: Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.
authors.forename: Maristela L
authors.initials: ML
authors.lastname: Onozato
authors.forename: Stephen
authors.initials: S
authors.lastname: Hammond
authors.forename: Mark
authors.initials: M
authors.lastname: Merren
authors.forename: Yukako
authors.initials: Y
authors.lastname: Yagi
mesh_terms: D001331:Automation / Q000295:instrumentation; D004867:Equipment Design; D016591:Histocytological Preparation Techniques / Q000295:instrumentation*; D006801:Humans; D016612:Paraffin Embedding / Q000295:instrumentation; D010338:Pathology, Clinical / Q000295:instrumentation*; D013048:Specimen Handling / Q000295:instrumentation*