title: Design of a "turn-off/turn-on" biosensor: understanding carbohydrate-lectin interactions for use in noncovalent drug delivery.
abstract: A low-cost and highly sensitive biosensor system is designed to investigate carbohydrate-lectin interactions. This combination of glyco-gold nanoparticles and boronic acid biosensor system opens a way to study noncovalent drug delivery.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical & Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371.
authors.forename: Bala Kishan
authors.initials: BK
authors.lastname: Gorityala
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Lu
authors.forename: Min Li
authors.initials: ML
authors.lastname: Leow
authors.forename: Jimei
authors.initials: J
authors.lastname: Ma
authors.forename: Xue-Wei
authors.initials: XW
authors.lastname: Liu
mesh_terms: D015374:Biosensing Techniques; D002241:Carbohydrates / Q000737:chemistry*; D016503:Drug Delivery Systems; D037102:Lectins / Q000737:chemistry*; D053758:Nanoparticles; D013050:Spectrometry, Fluorescence
chemical_list: D002241:Carbohydrates; D037102:Lectins