title: Dental age assessment of young Iranian adults using third molars: A multivariate regression study.
abstract: BACKGROUND
  In recent years, a noticeable increase in forensic age estimations of living individuals has been observed. Radiologic assessment of the mineralisation stage of third molars is of particular importance, with regard to the relevant age group. To attain a referral database and regression equations for dental age estimation of unaccompanied minors in an Iranian population was the goal of this study. Moreover, determination was made concerning the probability of an individual being over the age of 18 in case of full third molar(s) development.
  
  
  METHODS
  Using the scoring system of Gleiser and Hunt, modified by Köhler, an investigation of a cross-sectional sample of 1274 orthopantomograms of 885 females and 389 males aged between 15 and 22 years was carried out. Using kappa statistics, intra-observer reliability was tested. With Spearman correlation coefficient, correlation between the scores of all four wisdom teeth, was evaluated. We also carried out the Wilcoxon signed-rank test on asymmetry and calculated the regression formulae.
  
  
  RESULTS
  A strong intra-observer agreement was displayed by the kappa value. No significant difference (p-value for upper and lower jaws were 0.07 and 0.59, respectively) was discovered by Wilcoxon signed-rank test for left and right asymmetry. The developmental stage of upper right and upper left third molars yielded the greatest correlation coefficient. The probability of an individual being over the age of 18 is 95.6% for males and 100.0% for females in case four fully developed third molars are present. Taking into consideration gender, location and number of wisdom teeth, regression formulae were arrived at.
  
  
  CONCLUSIONS
  Use of population-specific standards is recommended as a means of improving the accuracy of forensic age estimates based on third molars mineralisation. To obtain more exact regression formulae, wider age range studies are recommended.
authors.affiliation: Oral & Maxillofacial Radiology, Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, P.O. Box 91735-984, Mashhad, Iran. bagherpour.ali@gmail.com
authors.forename: Ali
authors.initials: A
authors.lastname: Bagherpour
authors.forename: Najmeh
authors.initials: N
authors.lastname: Anbiaee
authors.forename: Parnia
authors.initials: P
authors.lastname: Partovi
authors.forename: Shayan
authors.initials: S
authors.lastname: Golestani
authors.forename: Shakiba
authors.initials: S
authors.lastname: Afzalinasab
mesh_terms: D000293:Adolescent; D000328:Adult; D000366:Age Determination by Teeth / Q000379:methods*; D003430:Cross-Sectional Studies; D005260:Female; D005553:Forensic Dentistry; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007492:Iran; D008297:Male; D008964:Molar, Third / Q000000981:diagnostic imaging / Q000254:growth & development*; D011862:Radiography, Panoramic; D012044:Regression Analysis; D014074:Tooth Calcification; D055815:Young Adult