title: Selective serotonin re-uptake inhibitors (SSRIs) in the aquatic environment: an ecopharmacovigilance approach.
abstract: Selective serotonin re-uptake inhibitors (SSRIs) antidepressants are among the most prescribed pharmaceutical active substances throughout the world. The occurrence of these widely used compounds in different environmental compartments (wastewaters, surface, ground and drinking waters, and sediments), justify the growing concern about these emerging environmental pollutants. Viewing an ecopharmacovigilance approach, a comprehensive discussion of the state of the art regarding different contamination sources, fate, degradation and occurrence is presented. Information on the current distribution levels and fate in different environmental matrices continues to be sparse and measures are imperative to improve awareness and encourage precautionary actions to minimize SSRIs' environmental impact.
authors.affiliation: Group of Health Surveillance, Center of Pharmaceutical Studies, Faculty of Pharmacy, University of Coimbra, Polo III, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal. uc20042648@student.ff.uc.pt
authors.forename: Liliana J G
authors.initials: LJ
authors.lastname: Silva
authors.forename: Celeste M
authors.initials: CM
authors.lastname: Lino
authors.forename: Leonor M
authors.initials: LM
authors.lastname: Meisel
authors.forename: Angelina
authors.initials: A
authors.lastname: Pena
mesh_terms: D018687:Antidepressive Agents, Second-Generation / Q000032:analysis* / Q000378:metabolism; D004777:Environment; D004784:Environmental Monitoring / Q000379:methods*; D006801:Humans; D017367:Selective Serotonin Reuptake Inhibitors / Q000032:analysis* / Q000378:metabolism; D014867:Water / Q000032:analysis*; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000378:metabolism; D018508:Water Purification
chemical_list: D018687:Antidepressive Agents, Second-Generation; D017367:Selective Serotonin Reuptake Inhibitors; D014867:Water; D014874:Water Pollutants, Chemical