title: A highly efficient green synthesis of N-alkyl 2-[(2-oxo-2-aryl ethyl) amino] benzamide derivatives from reaction of isatoic anhydride, primary amines and 2-bromoacethophenone.
abstract: N-alkyl 2-[(2-oxo-2-aryl ethyl)amino] benzamide derivatives have been synthesized in high yields. This involves three-component reaction of isatoic anhydride, primary amines in the presence of 2-bromoacethophenone derivatives. The reaction workup is simple and the products can be easily separated from the reaction mixture.
authors.affiliation: Chemistry Department, Faculty of Sciences, Shahid Rajaee Teacher Training University, Tehran, Iran. sabbaghan@srttu.edu
authors.forename: Maryam
authors.initials: M
authors.lastname: Sabbaghan
authors.forename: Zinatossadat
authors.initials: Z
authors.lastname: Hossaini
mesh_terms: D000098:Acetophenones / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D001549:Benzamides / Q000138:chemical synthesis* / Q000737:chemistry; D055772:Green Chemistry Technology; D015394:Molecular Structure; D010078:Oxazines / Q000737:chemistry*
chemical_list: C000590726:2-bromoacethophenone; D000098:Acetophenones; D000588:Amines; D001549:Benzamides; D010078:Oxazines; C037902:isatoic anhydride