title: Guanylate-binding proteins: niche recruiters for antimicrobial effectors.
abstract: There are fundamental questions regarding how IFN-γ activates host cells to eliminate intracellular pathogens. In this issue of Immunity, Yamamoto et al. (2012) demonstrate a critical role for the p65 guanylate-binding proteins (GBPs) in this process during infection with Toxoplasma gondii.
authors.affiliation: Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 380 South University Avenue, Philadelphia, PA 19104, USA.
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Dupont
authors.forename: Christopher A
authors.initials: CA
authors.lastname: Hunter