title: Why providers participate in clinical trials: considering the National Cancer Institute's Community Clinical Oncology Program.
abstract: BACKGROUND
  The translation of research evidence into practice is facilitated by clinical trials such as those sponsored by the National Cancer Institute's Community Clinical Oncology Program (CCOP) that help disseminate cancer care innovations to community-based physicians and provider organizations. However, CCOP participation involves unsubsidized costs and organizational challenges that raise concerns about sustained provider participation in clinical trials.
  
  
  OBJECTIVE
  This study was designed to improve our understanding of why providers participate in the CCOP in order to inform the decision-making process of administrators, clinicians, organizations, and policy-makers considering CCOP participation.
  
  
  METHODS
  We conducted a multi-site qualitative study of five provider organizations engaged with the CCOP. We interviewed 41 administrative and clinician key informants, asking about what motivated CCOP participation, and what benefits they associated with involvement. We deductively and inductively analyzed verbatim interview transcripts, and explored themes that emerged.
  
  
  RESULTS
  Interviewees expressed both "altruistic" and "self-interested" motives for CCOP participation. Altruistic reasons included a desire to increase access to clinical trials and feeling an obligation to patients. Self-interested reasons included the desire to enhance reputation, and a need to integrate disparate cancer care activities. Perceived benefits largely matched expressed motives for CCOP participation, and included internal and external benefits to the organization, and quality of care benefits for both patients and participating physicians.
  
  
  CONCLUSIONS
  The motives and benefits providers attributed to CCOP participation are consistent with translational research goals, offering evidence that participation can contribute value to providers by expanding access to innovative medical care for patients in need.
authors.affiliation: Department of Family Medicine, College of Medicine, The Ohio State University, Columbus, OH, USA. Ann.McAlearney@osumc.edu
authors.forename: Ann Scheck
authors.initials: AS
authors.lastname: McAlearney
authors.forename: Paula H
authors.initials: PH
authors.lastname: Song
authors.forename: Kristin L
authors.initials: KL
authors.lastname: Reiter
mesh_terms: D001291:Attitude of Health Personnel; D002986:Clinical Trials as Topic / Q000379:methods*; D055812:Community-Based Participatory Research / Q000458:organization & administration*; D003657:Decision Making; D006801:Humans; D008495:Medical Oncology; D009042:Motivation; D054547:National Cancer Institute (U.S.) / Q000458:organization & administration*; D010820:Physicians / Q000523:psychology*; D012107:Research Design; D057170:Translational Research, Biomedical / Q000458:organization & administration; D014481:United States