title: Asymmetric transfer hydrogenation of ketimines using well-defined iron(II)-based precatalysts containing a PNNP ligand.
abstract: Well-defined iron(II)-based complexes containing PNNP ligands catalyze a highly enantioselective reduction of N-(diphenylphosphinoyl)- and N-(p-tolylsulphonyl)-ketimines. Under mild conditions and low catalyst loading, the ketimines are successfully reduced to the corresponding amines in enantiomeric excess ranging from 94 to 99%.
authors.affiliation: Davenport Laboratory, Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario M5S 3H6, Canada.
authors.forename: Alexandre A
authors.initials: AA
authors.lastname: Mikhailine
authors.forename: Mazharul I
authors.initials: MI
authors.lastname: Maishan
authors.forename: Robert H
authors.initials: RH
authors.lastname: Morris
mesh_terms: D002384:Catalysis; D005296:Ferrous Compounds / Q000737:chemistry*; D006865:Hydrogenation; D007097:Imines / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D009570:Nitriles / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*
chemical_list: D005296:Ferrous Compounds; D007097:Imines; D008024:Ligands; D009570:Nitriles; D010720:Phosphines; C542835:ketimine