title: [Lung adenocarcinoma presented with reticular pattern in which both CA19-9 and carcinoembryonic antigen( CEA) were recognized as markers].
abstract: A 79-year-old male whose chest X-ray revealed a localized reticular shadow in health check was once treated medically with a diagnosis of interstitial pneumonia. Regardless of the treatment, the shadow increased in its size. Positron emission tomography (PET)-computed tomography(CT) was suggestive of a primary lung cancer in clinical stage IIIA. CA19-9 and CEA were 3,568.5 U/ml and 178.2 ng/ml respectively, and a left lower lobectomy was performed. The postoperative course was uneventful. Both tumor markers declined shortly after the surgery. But they increased in 8 months after the surgery associated with tumor recurrence. In spite of chemotherapy, the patient was expired 15 months following the surgery. Immunohistochemical staining showed the tumor was a well differentiated adenocarcinoma with positive findings of both CEA and CA19-9.
authors.affiliation: Department of Thoracic Surgery, Kanto Central Hospital, Tokyo, Japan.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Yoshitake
authors.forename: Hiroki
authors.initials: H
authors.lastname: Hayashi
authors.forename: Teruaki
authors.initials: T
authors.lastname: Oka
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Osada
authors.forename: Masaki
authors.initials: M
authors.lastname: Kawahara
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis*; D014408:Biomarkers, Tumor / Q000032:analysis*; D018395:CA-19-9 Antigen / Q000032:analysis*; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D003937:Diagnosis, Differential; D006801:Humans; D017563:Lung Diseases, Interstitial; D008175:Lung Neoplasms / Q000175:diagnosis*; D008297:Male; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor; D018395:CA-19-9 Antigen; D002272:Carcinoembryonic Antigen