title: Patient-specific factors in the proximity of the inferior alveolar nerve to the tooth apex.
abstract: OBJECTIVE
  To evaluate whether age and gender differences are predictive factors for inferior alveolar nerve position with respect to mandibular first molar roots.
  
  
  METHODS
  Cone-beam computed tomography scans [0.2-mm3 voxel size; n = 200 (100 males, 100 females)] of patients aged 15-65 years showing mandibular first and second molars were included in this study. Patients with pathoses that might affect inferior alveolar nerve position, including second molar and/or first premolar extraction, were excluded. Fourteen measurements (mm) were taken from the inferior alveolar nerve to the mesial and distal root apices. Subjects were grouped by age and gender. Data were analysed using two-way analyses of variance with post hoc Bonferroni corrections.
  
  
  RESULTS
  The distance from the inferior alveolar nerve to the root apices was smaller in females than males, regardless of age (p < 0.01). Distal roots were closer to the nerve than mesial roots in both genders (p < 0.05). Total buccolingual mandibular length (at 3-mm apical level) was shorter in females than males (p < 0.01) but mean buccolingual mandibular width at the level of the inferior alveolar canal did not differ. Nerve-root apex distances were significantly shorter in males and females aged 16-25 and 56-65 years than in other age groups (p < 0.01).
  
  
  CONCLUSIONS
  The distance between inferior alveolar nerve and mandibular first molar roots depends upon the age and gender: it is shorter in females than in males and in subjects aged 16-25 years and >55 years than in other age groups.
authors.affiliation: Dicle University, Faculty of Dentistry, Department of Endodontics, Diyarbakir, Turkey.
authors.forename: Özkan
authors.initials: Ö
authors.lastname: Adigüzel
authors.forename: Senem
authors.initials: S
authors.lastname: Yiğit-Özer
authors.forename: Sadullah
authors.initials: S
authors.lastname: Kaya
authors.forename: Zeki
authors.initials: Z
authors.lastname: Akkuş
mesh_terms: D000293:Adolescent; D000328:Adult; D054893:Cone-Beam Computed Tomography; D005260:Female; D006801:Humans; D008297:Male; D008340:Mandibular Nerve / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D008875:Middle Aged; D008963:Molar; D012727:Sex Characteristics; D019227:Tooth Apex / Q000000981:diagnostic imaging / Q000294:innervation*; D055815:Young Adult