title: Anesthetic management of a parturient with neuromyelitis optica.
abstract: Women with neuromyelitis optica, an acute inflammatory demyelinating condition of the central nervous system, have an unpredictable clinical course in pregnancy. Providing neuraxial anesthesia for these patients is controversial, although relapses may occur after exposure to either general or neuraxial anesthesia and are common. We report the successful obstetric anesthesia management of a parturient with neuromyelitis optica, review the medical literature, and discuss specific considerations for obstetric anesthesia in patients with underlying demyelinating disease.
authors.affiliation: Department of Anesthesiology, Brigham and Women’s Hospital, Boston, MA, USA. Neeti-Sadana@ouhsc.edu
authors.forename: N
authors.initials: N
authors.lastname: Sadana
authors.forename: M
authors.initials: M
authors.lastname: Houtchens
authors.forename: M K
authors.initials: MK
authors.lastname: Farber
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000701:Analgesics, Opioid / Q000627:therapeutic use; D000732:Androstanols; D000768:Anesthesia, General / Q000379:methods*; D000773:Anesthesia, Obstetrical / Q000379:methods*; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D058846:Antibodies, Monoclonal, Murine-Derived / Q000627:therapeutic use; D017604:Cesarean Section, Repeat / Q000379:methods*; D005260:Female; D005283:Fentanyl; D005500:Follow-Up Studies; D006801:Humans; D007136:Immunoglobulins / Q000627:therapeutic use; D007155:Immunologic Factors / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging / Q000379:methods; D008738:Methyl Ethers; D003473:Neuromuscular Nondepolarizing Agents; D009471:Neuromyelitis Optica / Q000150:complications* / Q000188:drug therapy; D010100:Oxygen / Q000008:administration & dosage; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control*; D011247:Pregnancy; D011248:Pregnancy Complications; D015742:Propofol; D000069283:Rituximab; D000077123:Rocuronium; D000077149:Sevoflurane; D013116:Spinal Cord / Q000473:pathology
chemical_list: D000305:Adrenal Cortex Hormones; D000701:Analgesics, Opioid; D000732:Androstanols; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D058846:Antibodies, Monoclonal, Murine-Derived; D007136:Immunoglobulins; D007155:Immunologic Factors; D008738:Methyl Ethers; D003473:Neuromuscular Nondepolarizing Agents; D000077149:Sevoflurane; D000069283:Rituximab; D010100:Oxygen; D005283:Fentanyl; D000077123:Rocuronium; D015742:Propofol