title: Effect of micro-arc oxidation surface modification on the properties of the NiTi shape memory alloy.
abstract: In this paper, the effects of micro-arc oxidation (MAO) surface modification (alumina coatings) on the phase transformation behavior, shape memory characteristics, in vitro haemocopatibility and cytocompatibility of the biomedical NiTi alloy were investigated respectively by differential scanning calorimetry, bending test, hemolysis ratio test, dynamic blood clotting test, platelet adhesion test and cytotoxicity testing by human osteoblasts (Hobs). The results showed that there were no obvious changes of the phase transformation temperatures and shape memory characteristics of the NiTi alloy after the MAO surface modification and the coating could withstand the thermal shock and volume change caused by martensite-austenite phase transformation. Compared to the uncoated NiTi alloys, the MAO surface modification could effectively improve the haemocopatibility of the coated NiTi alloys by the reduced hemolysis ratio, the prolonged dynamic clotting time and the decreased number of platelet adhesion; and the rough and porous alumina coatings could obviously promote the adherence, spread and proliferation of the Hobs with the significant increase of proliferation number of Hobs adhered on the surface of the coated NiTi alloys (P < 0.05).
authors.affiliation: School of Materials Science and Engineering, Nanchang Hangkong University, Nanchang, 330063, People's Republic of China. jlxu@nchu.edu.cn
authors.forename: J L
authors.initials: JL
authors.lastname: Xu
authors.forename: Z C
authors.initials: ZC
authors.lastname: Zhong
authors.forename: D Z
authors.initials: DZ
authors.lastname: Yu
authors.forename: F
authors.initials: F
authors.lastname: Liu
authors.forename: J M
authors.initials: JM
authors.lastname: Luo
mesh_terms: D000537:Aluminum Oxide / Q000737:chemistry; D001672:Biocompatible Materials / Q000737:chemistry; D049109:Cell Proliferation; D002470:Cell Survival; D002516:Ceramics; D003722:Dental Alloys / Q000737:chemistry; D006801:Humans; D008422:Materials Testing / Q000379:methods*; D009532:Nickel / Q000737:chemistry; D010973:Platelet Adhesiveness; D013499:Surface Properties; D013696:Temperature; D013997:Time Factors; D014025:Titanium / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D003722:Dental Alloys; C040654:titanium nickelide; C093826:Austenite; D009532:Nickel; D014025:Titanium; D000537:Aluminum Oxide