title: Regression of mesenchymal hamartoma of the liver with sarcoma chemotherapy.
abstract: We present a young patient with metastatic Ewing sarcoma that had hepatic lesions. As we were unaware of hepatic metastases in Ewing sarcoma, liver biopsy was performed. The pathologic findings were diagnostic of mesenchymal hamartoma of the liver. Surprisingly, the combined chemotherapy for metastatic sarcoma resulted in almost complete resolution of the hamartoma in the liver. This option may be useful in extreme cases when resection is not feasible.
authors.affiliation: Pediatric Hematology and Blood Coagulation Service, Western Galilee Hospital, Naharia, Israel. amir.kuperman@naharia.health.gov.il
authors.forename: Amir A
authors.initials: AA
authors.lastname: Kuperman
authors.forename: Liora
authors.initials: L
authors.lastname: Kornreich
authors.forename: Meora
authors.initials: M
authors.lastname: Feinmesser
authors.forename: Shifra
authors.initials: S
authors.lastname: Ash
authors.forename: Issac
authors.initials: I
authors.lastname: Yaniv
authors.forename: Ian J
authors.initials: IJ
authors.lastname: Cohen
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000175:diagnosis*; D003520:Cyclophosphamide / Q000008:administration & dosage; D003609:Dactinomycin / Q000008:administration & dosage; D003951:Diagnostic Errors; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006222:Hamartoma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008648:Mesoderm / Q000473:pathology*; D011379:Prognosis; D012512:Sarcoma, Ewing / Q000175:diagnosis*; D014750:Vincristine / Q000008:administration & dosage; D055815:Young Adult
chemical_list: D003609:Dactinomycin; D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D007069:Ifosfamide