title: [Influences of high-field intraoperative magnetic resonance imaging on the extent of resection in low-grade gliomas].
abstract: OBJECTIVE
  To evaluate the influences of high-field intraoperative magnetic resonance imaging (iMRI) on the extent of resection (EoR) in low-grade gliomas.
  
  
  METHODS
  Fifty-nine patients with low-grade gliomas underwent microsurgeries under the guidance of high-field iMRI and functional neuro-navigation. The rates of gross total removal and EoR were recorded after initial and final iMRI scans and neurological performances were evaluated peri-operatively and at follow-up.
  
  
  RESULTS
  iMRI and functional neuronavigation were successfully performed in all patients. Initial iMRI found that the rates of gross total removal were misestimated in 21 cases (35.6%). In 17 cases (28.8%), initial iMRI revealed resectable residual tumors and further resection achieved gross total removal in 8 cases (13.6%). iMRI boosted the level of EoR from 90% ± 15% to 94% ± 12% (P < 0.001) in all cases and from 78% ± 17% to 91% ± 12% in 17 cases undergoing further tumor resections. At 3-month follow-up, 2 cases (3.4%) developed neurological deficits.
  
  
  CONCLUSIONS
  The combination of iMRI and functional neuronavigation helped maximize safe tumor resection in low-grade gliomas.
authors.affiliation: Department of Neurosurgery, PLA General Hospital, Beijing 100853, China.
authors.forename: Jia-shu
authors.initials: JS
authors.lastname: Zhang
authors.forename: Xiao-lei
authors.initials: XL
authors.lastname: Chen
authors.forename: Fang-ye
authors.initials: FY
authors.lastname: Li
authors.forename: Jin-jiang
authors.initials: JJ
authors.lastname: Li
authors.forename: Gang
authors.initials: G
authors.lastname: Zheng
authors.forename: Ting
authors.initials: T
authors.lastname: Zhang
authors.forename: Shen
authors.initials: S
authors.lastname: Hu
authors.forename: Bai-nan
authors.initials: BN
authors.lastname: Xu
mesh_terms: D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D005910:Glioma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D038361:Neuronavigation / Q000379:methods; D016896:Treatment Outcome; D055815:Young Adult