title: NAVAGATE: a rubric to move from pharmacogenomics science to pharmacogenomics practice.
abstract: Integration of pharmacogenomic data at the point of care is the next essential step in translating years of research into evidence-based decisions that impact the care of an individual patient. The use of clinical recommendations for pharmacogenomic data help clinicians to better select and monitor drug therapy. However, a systematic rubric for utilizing the data ensures a thorough implementation of the information in a way that may improve the application of the new scientific discoveries. NAVAGATE is a set of eight questions to ask when considering a pharmacogenomic test or test result when caring for a patient. The series of questions are meant to inform prescribing or dispensing when obtaining or employing pharmacogenomic data for these steps within the medical-care framework. In this article two key examples are used to exemplify the benefits of following a systematic process to evaluate the utility of the new scientific data.
authors.affiliation: Institute for Pharmacogenomics & Individualized Therapy, UNC Eshelman School of Pharmacy, Department of Family Medicine, University of North Carolina at Chapel Hill, 120 Mason Farm Road, Campus Box 7361, Chapel Hill, NC 27599-7361, USA. mroederer@unc.edu
authors.forename: Mary W
authors.initials: MW
authors.lastname: Roederer
mesh_terms: D003658:Decision Making, Computer-Assisted; D019317:Evidence-Based Medicine; D006801:Humans; D010597:Pharmacogenetics; D057285:Precision Medicine