title: HPLC-HG-ICP-MS: a sensitive and selective method for inorganic arsenic in seafood.
abstract: The addition of an online post-column hydride generation (HG) step to the commonly used high-performance liquid chromatography inductively coupled plasma-mass spectrometry (HPLC-ICP-MS) setup for arsenic speciation proved to significantly improve the detection limits for the determination of inorganic arsenic (iAs) as arsenate in seafood samples, where the limit of detection and limit of quantification were found to be 0.0004 and 0.0014 mg kg(-1), respectively with HG. HG as an additional step further added to the selectivity of the determination of the iAs species and increased the detection and quantification of low levels of iAs (<0.002 mg kg(-1)) in samples with complicated matrices.
authors.affiliation: TESLA-Trace Element Speciation Laboratory, Chemistry, College of Physical Sciences, University of Aberdeen, Aberdeen, UK.
authors.forename: Asta H
authors.initials: AH
authors.lastname: Pétursdóttir
authors.forename: Helga
authors.initials: H
authors.lastname: Gunnlaugsdóttir
authors.forename: Hrönn
authors.initials: H
authors.lastname: Jörundsdóttir
authors.forename: Adrien
authors.initials: A
authors.lastname: Mestrot
authors.forename: Eva M
authors.initials: EM
authors.lastname: Krupp
authors.forename: Jörg
authors.initials: J
authors.lastname: Feldmann
mesh_terms: D000818:Animals; D001151:Arsenic / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D059022:Food Safety / Q000379:methods*; D057230:Limit of Detection; D011786:Quality Control; D017747:Seafood / Q000032:analysis* / Q000592:standards; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D001151:Arsenic