title: Ocular toxocariasis.
abstract: Ocular toxocariasis is an uncommon worldwide parasitic infection that affects mostly children and is found in both rural and metropolitan areas. In many parts of the world, parasitic infections of the eye are a major cause of blindness. The diagnosis of toxocariasis is essentially clinical, based on the lesion morphology and supportive laboratory data such as serum enzyme-linked immunosorbent assay (ELISA) titers and ELISA Toxocara titers on aqueous humor; other diagnostic methods are imaging studies including optical coherence tomography, fluorescein angiography, computed tomography, and ocular ultrasound. Treatment is directed at complications arising from intraocular inflammation and vitreous membrane traction. Early vitrectomy may be of value both diagnostically and therapeutically.
authors.affiliation: Retina Division, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA. arevalojf@jhmi.edu
authors.forename: J Fernando
authors.initials: JF
authors.lastname: Arevalo
authors.forename: Juan V
authors.initials: JV
authors.lastname: Espinoza
authors.forename: Fernando A
authors.initials: FA
authors.lastname: Arevalo
mesh_terms: D000909:Antibodies, Helminth / Q000097:blood; D001082:Aqueous Humor / Q000469:parasitology; D004797:Enzyme-Linked Immunosorbent Assay; D015822:Eye Infections, Parasitic / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D005451:Fluorescein Angiography; D006801:Humans; D012164:Retinal Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D041623:Tomography, Optical Coherence; D014057:Tomography, X-Ray Computed; D014120:Toxocariasis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy; D014463:Ultrasonography
chemical_list: D000909:Antibodies, Helminth