title: IgG4-related systemic disease presenting with lung entrapment and constrictive pericarditis.
abstract: We describe a 29-year-old woman who presented with chronic pleuropericarditis complicated by lung entrapment and constrictive pericarditis. Pleural biopsy performed during the decortication procedure revealed fibrinous pleuritis with lymphoplasmacytic inflammation including IgG4-positive plasma cells. The patient responded favorably to corticosteroid therapy with resolution of pleural effusion and constrictive physiology. To our knowledge, this is the first reported case of IgG4-related systemic disease manifesting as lung entrapment and constrictive pericarditis.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN. Electronic address: sekiguchi.hiroshi@mayo.edu.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sekiguchi
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
authors.forename: Ryohei
authors.initials: R
authors.lastname: Horie
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
authors.forename: James P
authors.initials: JP
authors.lastname: Utz
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
authors.forename: Jay H
authors.initials: JH
authors.lastname: Ryu
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism*; D008168:Lung / Q000378:metabolism / Q000473:pathology; D010493:Pericarditis / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology*; D010494:Pericarditis, Constrictive / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D010950:Plasma Cells / Q000378:metabolism / Q000473:pathology; D010998:Pleurisy / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D007074:Immunoglobulin G