title: Copper(I)-catalyzed formal carboboration of alkynes: synthesis of tri- and tetrasubstituted vinylboronates.
abstract: The first copper-catalyzed formal carboboration of alkynes, in which a C-B bond and a C-C bond are created in a single catalytic cycle, is presented. The reaction proceeds with high regioselectivity and syn-stereoselectivity to form tri- and tetrasubstituted vinylboronic esters from commercially available bis(pinacolato)diboron. A subsequent cross-coupling reaction gives access to highly substituted alkenes.
authors.affiliation: Departamento de Química Orgánica (módulo 01), Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Alfaro
authors.forename: Alejandro
authors.initials: A
authors.lastname: Parra
authors.forename: José
authors.initials: J
authors.lastname: Alemán
authors.forename: José Luis
authors.initials: JL
authors.lastname: García Ruano
authors.forename: Mariola
authors.initials: M
authors.lastname: Tortosa