title: IL-17A is a central regulator of lung tumor growth.
abstract: In a recent study we reported increased expression of IL-17A in the lung of patients with lung adenocarcinoma. Local blockade of IL-17A in the lung, in a model of lung cancer revealed enhanced anti-tumor immunity characterized by increased IFNγ, a diminished T-regulatory cell number and reduced tumor growth.
authors.affiliation: Laboratories of Cellular and Molecular Lung Immunology; Institute of Molecular Pneumology; Friedrich-Alexander-Universität; Erlangen-Nürnberg, Germany.
authors.forename: Sarah
authors.initials: S
authors.lastname: Reppert
authors.forename: Sonja
authors.initials: S
authors.lastname: Koch
authors.forename: Susetta
authors.initials: S
authors.lastname: Finotto