title: Reversible paresis of the left hand related to a migraine without aura attack.
abstract: BACKGROUND
  The comorbidity between migraine and stroke continues to be a debated topic. Prior cases of reversible neuroradiologic lesions have been described in migrainous patients and in particular for those suffering from migraine with aura or complicated migraine attacks.
  
  
  METHODS
  We describe a patient that presented with a migraine without aura (MO) attack followed by paresis of the left hand that resolved completely within 4 days. An early brain magnetic resonance image (MRI) showed congruent cytotoxic-like alteration, whereas the lesion was no longer detectable on a standard 8-day MRI follow-up. A focused high-resolution MRI disclosed a very small cortical lesion, whereas a functional MRI demonstrated normal activation of the previously affected cortex at 8-month follow-up.
  
  
  CONCLUSIONS
  This MO patient presented with an ischemic-like lesion associated with migraine that reversed completely on MRI examination suggesting that migrainous infarction can occur in MO. Focused high-resolution sequences at follow-up might disclose subtle cortical lesions that could be more frequent than thought, coexisting with the well-known white matter hyperintensities not associated with neurological signs.
authors.affiliation: Department of Neurosciences, Headache Centre, University of Padua, Padua, Italy. ferdinando.maggioni@unipd.it
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Maggioni
authors.forename: Federica
authors.initials: F
authors.lastname: Viaro
authors.forename: Renzo
authors.initials: R
authors.lastname: Manara
authors.forename: Valentina
authors.initials: V
authors.lastname: Citton
authors.forename: Giorgio
authors.initials: G
authors.lastname: Zanchin
mesh_terms: D002545:Brain Ischemia / Q000150:complications* / Q000473:pathology; D005260:Female; D059907:Functional Neuroimaging; D006225:Hand; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D020326:Migraine without Aura / Q000150:complications* / Q000473:pathology; D009044:Motor Cortex / Q000473:pathology*; D010291:Paresis / Q000150:complications* / Q000473:pathology; D020521:Stroke / Q000150:complications* / Q000473:pathology