title: Factor XIII Deficiency in Siblings: Importance of Prophylactic Replacement.
abstract: Factor XIII deficiency, an autosomal recessive trait, can result in serious bleeding manifestation. This case report presents two brothers with Factor XIII deficiency. Though the younger sibling had been screened and diagnosed prophylactic replacement therapy had not been initiated unlike the elder brother. He presented with intracranial haemorrhage needing surgical evacuation while the elder brother remained symptom free on regular prophylactic replacement of FFP.
authors.affiliation: The Department of Pediatrics, Kasturba Medical College, Madhavanagar, Manipal, Karnataka 576104 India.
authors.forename: Kiran
authors.initials: K
authors.lastname: Kini
authors.forename: Deepti
authors.initials: D
authors.lastname: Chopra
authors.forename: Pushpa G
authors.initials: PG
authors.lastname: Kini