title: A nomogram for predicting lymph node metastasis of presumed stage I and II endometrial cancer.
abstract: OBJECTIVE
  Our objective was to develop a nomogram based on pathological hysterectomy characteristics to provide a more individualized and accurate estimation of lymph node metastasis in endometrial cancer.
  
  
  METHODS
  Data from the Surveillance, Epidemiology, and End Results database for 18,294 patients who underwent hysterectomy and lymphadenectomy were analyzed. A multivariate logistic regression analysis of selected prognostic features was performed, and a nomogram to predict lymph node metastasis was constructed. A cohort of 434 patients was used for the external validation.
  
  
  RESULTS
  The nomogram showed good discrimination with an area under the receiver operating characteristic curve of 0.80 (95% confidence interval, 0.79-0.81) in the training set and 0.79 (95% confidence interval, 0.78-0.80) in the validation set. The nomogram was well calibrated.
  
  
  CONCLUSIONS
  We developed a nomogram based on 5 clinical and pathological characteristics to predict lymph node metastasis with a high concordance probability.
authors.affiliation: Department of Obstetrics and Gynecology, Hospital Tenon, Assistance Publique-Hôpitaux de Paris, France.
authors.forename: Sofiane
authors.initials: S
authors.lastname: Bendifallah
authors.forename: Anne Sophie
authors.initials: AS
authors.lastname: Genin
authors.forename: Iptissem
authors.initials: I
authors.lastname: Naoura
authors.forename: Nathalie
authors.initials: N
authors.lastname: Chabbert Buffet
authors.forename: Francoise
authors.initials: F
authors.lastname: Clavel Chapelon
authors.forename: Bassam
authors.initials: B
authors.lastname: Haddad
authors.forename: Dominique
authors.initials: D
authors.lastname: Luton
authors.forename: Emile
authors.initials: E
authors.lastname: Darai
authors.forename: Roman
authors.initials: R
authors.lastname: Rouzier
authors.forename: Martin
authors.initials: M
authors.lastname: Koskas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009367:Neoplasm Staging; D049451:Nomograms; D055815:Young Adult