title: [Effects of calcium and vitamin D supplementations on cardiovascular disease: review article].
abstract: Studies exploring the effect of calcium supplementation on cardiovascular risk suggest that systolic blood pressure decreases with supplementation. A lower calcium intake has been associated with an increased risk of stroke. By contrast, calcium supplementation may increase the risk of myocardial infarction. The effect of vitamin D supplementation on blood pressure is still unclear and no effect of vitamin D supplementation on coronary heart disease or stroke has been clearly demonstrated. There is a lack of randomized clinical trials primarily addressing the effect of these parameters on CVD. Currently, the use of calcium and vitamin D supplementations for the prevention of cardiovascular disease is not justified.
authors.affiliation: Unité d'épidémiologie populationnelle, Département de médecine communautaire, de premier recours et des urgences, HUG, 1211 Genève 14. idris.guessous@hcuge.ch
authors.forename: I
authors.initials: I
authors.lastname: Guessous
authors.forename: M
authors.initials: M
authors.lastname: Bochud
mesh_terms: D001794:Blood Pressure / Q000187:drug effects; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D002136:Calcium, Dietary / Q000008:administration & dosage* / Q000009:adverse effects; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D006801:Humans; D014807:Vitamin D / Q000627:therapeutic use*
chemical_list: D050071:Bone Density Conservation Agents; D002136:Calcium, Dietary; D014807:Vitamin D