title: [The clinical value of autofluorescence bronchoscopy for the diagnosis of lung cancer].
abstract: OBJECTIVE
  To evaluate the benefit of using autofluorescence bronchoscopy (AFB) for the detection and localization of early invasive lung cancer.
  
  
  METHODS
  AFB and white light bronchoscopy (WLB) were performed on 198 cases of suspected lung cancer, and the relative sensitivity of WLB plus AFB compared with WLB alone.
  
  
  RESULTS
  Included 198 biopsy specimens, and 160 were classified as positive by pathology, including 156 invasive cancer and 4 severe dysplasia. The relative sensitivity to detect intraepithelial neoplasia of WLB + FLB versus WLB was 97.5% and 80.0% respectively, significantly (P < 0.05).
  
  
  CONCLUSIONS
  AFB was more sensitive than WLB in detecting preneoplastic bronchial changes and early lung cancer in high-risk subjects.
authors.affiliation: Department of Respiratory Medicine. The Second Xiangya Hospital Affiliated Central South University, Changsha 410011, China. zhulanyan8888@sina.com
authors.forename: Lan-yan
authors.initials: LY
authors.lastname: Zhu
authors.forename: Yu-jie
authors.initials: YJ
authors.lastname: Xu
authors.forename: Ding
authors.initials: D
authors.lastname: Liang
authors.forename: Ping
authors.initials: P
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001999:Bronchoscopy; D002283:Carcinoma, Bronchogenic / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity