title: Relationship of central and peripheral blood pressure to left ventricular mass in hypertensive patients.
abstract: OBJECTIVE
  The purpose of the present study was to assess the relationship of central and peripheral blood pressure to left ventricular mass.
  
  
  METHODS
  Cross-sectional study that included 392 never treated hypertensive individuals. Measurement of office, 24-h ambulatory, and central blood pressure (obtained using applanation tonometry) and determination of left ventricular mass by echocardiography were performed in all patients.
  
  
  RESULTS
  In a multiple regression analysis, with adjustment for age, gender and metabolic syndrome, 24-h blood pressure was more closely related to ventricular mass than the respective office and central blood pressures. Systolic blood pressures always exhibited a higher correlation than diastolic blood pressures in all 3 determinations. The correlation between left ventricular mass index and 24-h systolic blood pressure was higher than that of office (P<.002) or central systolic blood pressures (P<.002). Changes in 24-h systolic blood pressure caused the greatest variations in left ventricular mass index (P<.001).
  
  
  CONCLUSIONS
  In our population of untreated middle-aged hypertensive patients, left ventricular mass index is more closely related to 24-h ambulatory blood pressure than to office or central blood pressure. Central blood pressure does not enable us to better identify patients with left ventricular hypertrophy.
authors.affiliation: Unidad de Hipertensión y Riesgo Vascular, Servicio de Medicina Interna, Hospital de Sagunto, Sagunto, Valencia, España.
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Pérez-Lahiguera
authors.forename: Enrique
authors.initials: E
authors.lastname: Rodilla
authors.forename: Jose A
authors.initials: JA
authors.lastname: Costa
authors.forename: Carmen
authors.initials: C
authors.lastname: Gonzalez
authors.forename: Joaquin
authors.initials: J
authors.lastname: Martín
authors.forename: Jose M
authors.initials: JM
authors.lastname: Pascual
mesh_terms: D000328:Adult; D000368:Aged; D062186:Arterial Pressure / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology*; D018660:Blood Pressure Monitoring, Ambulatory; D003430:Cross-Sectional Studies; D004452:Echocardiography; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged