title: Stereocontrolled intramolecular iron-mediated diene/vinyl ether cyclocoupling reactions.
abstract: A stereocontrolled intramolecular iron-mediated diene/olefin cyclocoupling reaction has been explored using vinyl ethers as the olefin partners. Spirolactams with functionalized (alkoxymethyl) side chains can be formed under thermal conditions. With a methoxy substituent on the diene, demetalation and hydrolysis of the cyclocoupling product afforded a single diastereomer.
authors.affiliation: Department of Chemistry, Case Western Reserve University, Cleveland, Ohio 44106, United States. ajp4@case.edu
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Pearson
authors.forename: Sheng
authors.initials: S
authors.lastname: Zhang
authors.forename: Huikai
authors.initials: H
authors.lastname: Sun