title: Social inclusion enhances biological motion processing: a functional near-infrared spectroscopy study.
abstract: Humans are especially tuned to the movements of other people. Neural correlates of this social attunement have been proposed to lie in and around the right posterior superior temporal sulcus (STS) region, which robustly responds to biological motion in contrast to a variety of non-biological motions. This response persists even when no form information is provided, as in point-light displays (PLDs). The aim of the current study was to assess the ability of functional near-infrared spectroscopy (fNIRS) to reliably measure brain responses to PLDs of biological motion, and determine the sensitivity of these responses to interpersonal contextual factors. To establish reliability, we measured brain activation to biological motion with fNIRS and functional magnetic resonance imaging (fMRI) during two separate sessions in an identical group of 12 participants. To establish sensitivity, brain responses to biological motion measured with fNIRS were subjected to an additional social manipulation where participants were either socially included or excluded before viewing PLDs of biological motion. Results revealed comparable brain responses to biological motion using fMRI and fNIRS in the right supramarginal gyrus. Further, social inclusion increased brain responses to biological motion in right supramarginal gyrus and posterior STS. Thus, fNIRS can reliably measure brain responses to biological motion and can detect social experience-dependent modulations of these brain responses.
authors.affiliation: Yale Child Study Center, Yale University School of Medicine, 230 South Frontage Road, New Haven, CT 06520, USA. danielle.bolling@yale.edu
authors.forename: Danielle Z
authors.initials: DZ
authors.lastname: Bolling
authors.forename: Kevin A
authors.initials: KA
authors.lastname: Pelphrey
authors.forename: Martha D
authors.initials: MD
authors.lastname: Kaiser
mesh_terms: D000328:Adult; D001921:Brain / Q000033:anatomy & histology / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods; D005260:Female; D059907:Functional Neuroimaging / Q000379:methods*; D006801:Humans; D007398:Interpersonal Relations; D008279:Magnetic Resonance Imaging; D008297:Male; D009039:Motion Perception / Q000502:physiology*; D010775:Photic Stimulation; D015203:Reproducibility of Results; D012934:Social Isolation; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D013702:Temporal Lobe / Q000033:anatomy & histology / Q000502:physiology