title: Porcine model of intracoronary pulverization of stent struts by rotablation atherectomy.
abstract: OBJECTIVE
  To evaluate the feasibility and safety of rotablation atherectomy in a suboptimally expanded stent.
  
  
  METHODS
  Seven pigs underwent suboptimal stent expansion in the left anterior descending coronary. Pulverization of the stent struts was performed by rotablation atherectomy with two different burr sizes. Two types of control porcine models were used: pigs with fully expanded stents and pigs without stents. Continuous electrocardiogram readings as well as microscopic and radiologic analysis of cardiac tissue were performed.
  
  
  RESULTS
  Rotablation atherectomy reduces the suboptimally expanded stent by (26.95 ± 5.03)%. Ninety-five percent of the metal microparticles, imbedded in the suboptimally expanded stent group cardiac tissue, are less than 15 μm. Transient vasospasm and ST segments elevations were observed during rotablation atherectomy, which returned to basal conditions at the end of the intervention.
  
  
  CONCLUSIONS
  Our study demonstrated the feasibility and safety of using rotablation atherectomy to pulverize stent struts in a suboptimally expanded stent.
authors.affiliation: Centre de Recherche, Hôpital du Sacré-Cœur de Montréal, Montréal, Québec, Canada.
authors.forename: Thuy Tran
authors.initials: TT
authors.lastname: Quang
authors.forename: Raja
authors.initials: R
authors.lastname: Hatem
authors.forename: Guy
authors.initials: G
authors.lastname: Rousseau
authors.forename: Bruno
authors.initials: B
authors.lastname: Dube
authors.forename: Caroline
authors.initials: C
authors.lastname: Samson
authors.forename: Erick
authors.initials: E
authors.lastname: Schampaert
authors.forename: Thierry
authors.initials: T
authors.lastname: Charron
mesh_terms: D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000295:instrumentation*; D000818:Animals; D017225:Atherectomy, Coronary / Q000009:adverse effects; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000175:diagnosis / Q000209:etiology; D003331:Coronary Vessels / Q000000981:diagnostic imaging; D020878:Device Removal / Q000009:adverse effects / Q000379:methods*; D005240:Feasibility Studies; D008297:Male; D008670:Metals; D023421:Models, Animal; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012307:Risk Factors; D015607:Stents; D013552:Swine; D013997:Time Factors; D018084:Ultrasonography, Interventional
chemical_list: D008670:Metals