title: Scleredema diabeticorum in a patient with type 2 diabetes mellitus.
abstract: Background. Scleredema adultorum, a connective tissue disorder of unknown aetiology, is characterized by a thickening of the reticular dermis in the upper back of the body that may decrease the mobility of the affected tissues. It has been reported in diabetic patients with poor metabolic control. Therapeutic options are limited with generally poor results. Case Report. 53-year-old white male with type 2 diabetes mellitus was referred to our department for evaluation of incipient nephropathy and retinopathy. On examination, he presented erythematous, indurated, painless and ill-defined plaque on the skin of the upper back with limited movement of shoulders. A biopsy was done revealing scleredema. PUVA treatment and physiotherapy were started with the amelioration of mobility and acquiring some elasticity of the upper back. Discussion. The development of scleredema in diabetic patients has been related to prolonged exposure to chronic hyperglycaemia. Our patient has had diabetes for 20 years with an acceptable glucose control, however he developed the scleredema 10 years ago. Conclusions. Scleredema is a rare connective disorder that seems to appear most frequently in diabetic subjects. Good metabolic control seems not to preclude its development. PUVA treatment and physiotherapy are therapeutic options that seem to be of some help.
authors.affiliation: Endocrinology and Nutrition Department, Fundación Jiménez Díaz-Capio, 28040 Madrid, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Martín
authors.forename: L
authors.initials: L
authors.lastname: Requena
authors.forename: K
authors.initials: K
authors.lastname: Manrique
authors.forename: F D
authors.initials: FD
authors.lastname: Manzarbeitia
authors.forename: A
authors.initials: A
authors.lastname: Rovira