title: Decidual stromal cells as regulators of T-cell access to the maternal-fetal interface.
abstract: A recent study in the journal Science offers insights into the mechanism behind feto-maternal tolerance, as evidenced by changes in the immuno-logical environment of the uterus and decidua. They also provide a rich area of research for the understanding of the regulation of the immune system in other complicated medical conditions, including cancer and pregnancies affected by infection or autoimmunity.
authors.affiliation: Reproductive Immunology Unit, Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.
authors.forename: Michelle
authors.initials: M
authors.lastname: Silasi
authors.forename: Gil
authors.initials: G
authors.lastname: Mor
mesh_terms: D000818:Animals; D002450:Cell Communication; D002465:Cell Movement / Q000187:drug effects; D060833:Cellular Microenvironment; D054357:Chemokine CXCL10 / Q000378:metabolism; D054370:Chemokine CXCL9 / Q000378:metabolism; D005260:Female; D006801:Humans; D007108:Immune Tolerance; D056747:Immunomodulation; D008431:Maternal-Fetal Exchange / Q000276:immunology*; D010617:Phenanthridines / Q000276:immunology*; D011247:Pregnancy; D017154:Stromal Cells / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D058408:Th1-Th2 Balance
chemical_list: D054357:Chemokine CXCL10; D054370:Chemokine CXCL9; D010617:Phenanthridines; C049749:decidium