title: Evaluation of serum lipid levels in children.
abstract: This study aimed to establish reference values for serum levels of total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) in children. The study included samples from 4,102 healthy children (2,003 boys and 2,099 girls) ages 1-18 years. The serum levels of total cholesterol, triglycerides, and HDL-C were determined using the Advia 2400 autoanalyzer. The LDL-C levels were calculated using the Friedewald equation. The mean, standard deviation, and 5th, 10th, 25th, 50th, 75th, 90th, and 95th percentile values of the biochemical parameters for boys and girls were detected. The total cholesterol and HDL-C levels were higher among the girls than among the boys in 15- to 18-year-old group. No significant difference was found for the other serum lipid levels among any of the age groups. This study provided pediatric reference intervals for the lipid parameters for children.
authors.affiliation: Department of Biochemistry, Faculty of Medicine, Bulent Ecevit University (formerly Karaelmas University), Zonguldak, Turkey. drcanmurat@yahoo.com
authors.forename: Murat
authors.initials: M
authors.lastname: Can
authors.forename: Ethem
authors.initials: E
authors.lastname: Piskin
authors.forename: Berrak
authors.initials: B
authors.lastname: Guven
authors.forename: Serefden
authors.initials: S
authors.lastname: Acikgoz
authors.forename: Gorkem
authors.initials: G
authors.lastname: Mungan
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015331:Cohort Studies; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood* / Q000175:diagnosis; D008075:Lipoproteins, HDL / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood*; D008297:Male; D012016:Reference Values; D018570:Risk Assessment; D012737:Sex Factors
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL