title: Selective syntheses of no-carrier-added 2- and 3-[18F]fluorohalopyridines through the radiofluorination of halopyridinyl(4'-methoxyphenyl)iodonium tosylates.
abstract: No-carrier-added 2- and 3-[(18)F]fluorohalopyridines were readily synthesized as potentially useful labeling synthons for prospective PET radiotracers through the selective radiofluorination of halopyridinyl(4'-methoxyphenyl)iodonium tosylates, themselves conveniently prepared in a single pot from iodohalopyridines.
authors.affiliation: Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room B3 C346A, 10 Center Drive, Bethesda, MD 20892-1003, USA.
authors.forename: Joong-Hyun
authors.initials: JH
authors.lastname: Chun
authors.forename: Victor W
authors.initials: VW
authors.lastname: Pike
mesh_terms: D001557:Benzenesulfonates / Q000737:chemistry*; D005462:Fluorine Radioisotopes / Q000737:chemistry; D049268:Positron-Emission Tomography; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry*; D019275:Radiopharmaceuticals / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: C573194:4-methylbenzenesulfonic acid; D001557:Benzenesulfonates; D005462:Fluorine Radioisotopes; D011725:Pyridines; D019275:Radiopharmaceuticals; C023666:pyridine