title: Angiofollicular lymphoid hyperplasia (Castleman disease) presenting as an isolated neck mass.
abstract: Castleman disease is a relatively uncommon lymphoproliferative disorder. A presentation as an isolated lesion in the neck is extremely rare. We report the case of a 26-year-old man who presented with a 4-month history of an enlarging right neck mass that was identified as Castleman disease on excisional biopsy. The biopsy was curative. In localized forms of Castleman disease, excisional biopsy is both diagnostic and curative. However, in multicentric forms, additional treatment is required.
authors.affiliation: InterMed Otolaryngology, Portland, ME 04101, USA. bliess@intermed.com
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Liess
authors.forename: Alan A
authors.initials: AA
authors.lastname: Alexander
authors.forename: Matthew E
authors.initials: ME
authors.lastname: Dahl
authors.forename: Robert P
authors.initials: RP
authors.lastname: Zitsch
authors.forename: Jason Scott
authors.initials: JS
authors.lastname: Holly
mesh_terms: D000328:Adult; D001706:Biopsy; D005871:Castleman Disease / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D009333:Neck / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed