title: Nasoalveolar molding in cleft care:  is it efficacious?
abstract: In the era of evidence-based medicine, new treatment protocols and interventions should be routinely evaluated for their efficacy by reviewing the available evidence. In the cleft literature, nasoalveolar molding has garnered attention over the last decade as a new option for improving nasal form and symmetry before primary surgical repair. Systematic review of the evidence is, however, currently lacking. This review evaluates whether nasoalveolar molding can improve nasal symmetry and form toward the norm, as well as whether nasoalveolar molding demonstrates advantages over other protocols in achieving this goal. A literature search of five databases plus relevant reference lists retrieved 98 articles regarding nasoalveolar molding, 21 of which reported objective outcome measures of nasal symmetry and form, and six of which were able to be given evidence level ratings, all in the unilateral cleft population. Statistical analysis was not possible given the range of techniques and outcomes. Studies of bilateral cleft were not given evidence level ratings, given the inability to separate the effects of nasoalveolar molding from other primary nasal interventions in studies that would have otherwise been rated. In unilateral cleft lip-cleft palate, there was some evidence that nasoalveolar molding may improve nasal outcomes, though comparison with other techniques was limited. Despite a relative paucity of high-level evidence, nasoalveolar molding appears to be a promising technique that deserves further study.
authors.affiliation: Boston, Mass. From Harvard Medical School; the Department of Plastic and Oral Surgery, Children's Hospital Boston; and the Department of Otolaryngology, Massachusetts Eye and Ear Infirmary.
authors.forename: Megan M
authors.initials: MM
authors.lastname: Abbott
authors.forename: John G
authors.initials: JG
authors.lastname: Meara
mesh_terms: D000539:Alveolar Process / Q000601:surgery*; D002971:Cleft Lip / Q000601:surgery*; D002972:Cleft Palate / Q000601:surgery*; D019317:Evidence-Based Medicine; D005146:Facial Asymmetry / Q000151:congenital / Q000517:prevention & control / Q000601:surgery; D006801:Humans; D063175:Mandibular Reconstruction / Q000379:methods; D009666:Nose / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods; D012225:Rhinoplasty / Q000379:methods