title: A score to predict the development of adverse clinical events after transition from acute hospital wards to post-acute care settings.
abstract: Adverse clinical events (ACEs) are common in post-acute hospital care. We aimed at developing and validating a method, able to be administered in hospital wards, for identifying elderly patients at increased risk of ACEs after transferral to post-acute care (PAC) facilities. This was a prospective observational study, including 502 patients admitted to 19 PAC facilities in northern Italy from July 1(st) to August 14(th), 2009. A standardized form was used to collect data. Variables showing stable association with ACEs in testing group were used to derive the score. The relative risk (RR) of developing ACEs according to the score was measured in the validation group. Age ≥87 years, delirium, pressure sore, indwelling bladder catheter, malnutrition, and acute infection on admission were identified as stable ACE predictors. A score of 1 was assigned to each predictor. Subjects were classified as having low (score=0), medium-low (score=1), medium-high (score=2-3), or high (score ≥4) risk of ACEs. The RR of developing ≥1 ACE increased progressively from low (RR=1) to medium-low (RR=1.5, 95% confidence interval [CI] 1.1-1.9), medium-high (RR=1.6, 95% CI 1.3-2.1), and high (RR=1.8, 95% CI 1.4-2.3) risk score. The RR of being not discharged to home increased monotonically from 1.0 in low-risk to 2.7 in high-risk groups. In conclusion, this study proposes a method, able to be administered in hospital wards, for identifying patients at increased risk of ACEs after transferral to PAC. The score might also be used to identify people who will not return to home after PAC discharge.
authors.affiliation: Department of Clinical and Preventive Medicine, University of Milano-Bicocca and Geriatric Clinic, S. Gerardo Hospital, Monza, Italy. giuseppe.bellelli@unimib.it
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Bellelli
authors.forename: Bruno
authors.initials: B
authors.lastname: Bernardini
authors.forename: Michela
authors.initials: M
authors.lastname: Pievani
authors.forename: Giovanni B
authors.initials: GB
authors.lastname: Frisoni
authors.forename: Antonio
authors.initials: A
authors.lastname: Guaita
authors.forename: Marco
authors.initials: M
authors.lastname: Trabucchi
mesh_terms: D000208:Acute Disease; D000368:Aged; D064420:Drug-Related Side Effects and Adverse Reactions / Q000209:etiology*; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D010362:Patients' Rooms; D012044:Regression Analysis; D015203:Reproducibility of Results; D012307:Risk Factors