title: Management and treatment of hepatitis B virus in patients with HIV infection: A practical guide for health care professionals.
abstract: The management and treatment of HIV and hepatitis B virus (HBV)-coinfected patients present specific challenges for clinicians. The morbidity and mortality related to these concomitant infections are growing concerns, while the use of antiviral drugs effective against both viruses complicates therapeutic decision making. The present document provides guidelines for physicians regarding care and treatment of patients coinfected with HIV and HBV. Primary prevention of HBV in HIV-positive patients is achieved through appropriate vaccination schedules. Follow-up before treatment of HBV may include liver biopsy, screening for hepatocellular carcinoma and testing for esophageal varicies in cases of cirrhosis. In HBV-infected patients requiring treatment, recommendations regarding initiation, duration and choice of first-line drugs are made. Finally, in the case of resistance, appropriate alternative therapies are necessary.
authors.affiliation: Division of Infectious Diseases and Immunodeficiency Service, McGill University Health Centre;
authors.forename: Marina B
authors.initials: MB
authors.lastname: Klein
authors.forename: Jean-Guy
authors.initials: JG
authors.lastname: Baril
authors.forename: Marc-André
authors.initials: MA
authors.lastname: Charron
authors.forename: Claude
authors.initials: C
authors.lastname: Fortin
authors.forename: Richard
authors.initials: R
authors.lastname: Lalonde
authors.forename: Marie-France
authors.initials: MF
authors.lastname: Matte
authors.forename: Marc
authors.initials: M
authors.lastname: Poliquin
authors.forename: Annie
authors.initials: A
authors.lastname: Talbot
authors.forename: Rachel
authors.initials: R
authors.lastname: Therrien
authors.forename: Cécile
authors.initials: C
authors.lastname: Tremblay
authors.forename: Benoît
authors.initials: B
authors.lastname: Trottier
authors.forename: Irina
authors.initials: I
authors.lastname: Tsarevsky
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Villeneuve