title: In vitro activities of nine antifungal drugs against 81 Phialophora and Cyphellophora isolates.
abstract: Cyphellophora guyanensis (n = 15), other Cyphellophora species (n = 11), Phialophora europaea (n = 43), and other Phialophora species (n = 12) were tested in vitro against nine antifungal drugs. The MIC(90)s across all of the strains (n = 81) were, in increasing order, as follows: posaconazole, 0.063 μg/ml; itraconazole, 0.5 μg/ml; voriconazole, 1 μg/ml; micafungin, 1 μg/ml; terbinafine, 2 μg/ml; isavuconazole, 4 μg/ml; caspofungin, 4 μg/ml; fluconazole, 8 μg/ml; amphotericin B, 16 μg/ml.
authors.affiliation: Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
authors.forename: Peiying
authors.initials: P
authors.lastname: Feng
authors.forename: M Javad
authors.initials: MJ
authors.lastname: Najafzadeh
authors.forename: Jiufeng
authors.initials: J
authors.lastname: Sun
authors.forename: Sarah
authors.initials: S
authors.lastname: Ahmed
authors.forename: Liyan
authors.initials: L
authors.lastname: Xi
authors.forename: G Sybren
authors.initials: GS
authors.lastname: de Hoog
authors.forename: Wei
authors.initials: W
authors.lastname: Lai
authors.forename: Chun
authors.initials: C
authors.lastname: Lu
authors.forename: Corné H
authors.initials: CH
authors.lastname: Klaassen
authors.forename: Jacques F
authors.initials: JF
authors.lastname: Meis
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology*; D000077336:Caspofungin; D054714:Echinocandins / Q000494:pharmacology; D015725:Fluconazole / Q000494:pharmacology; D017964:Itraconazole / Q000494:pharmacology; D055666:Lipopeptides / Q000494:pharmacology; D000077551:Micafungin; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects* / Q000254:growth & development; D009281:Naphthalenes / Q000494:pharmacology; D009570:Nitriles / Q000494:pharmacology; D010676:Phialophora / Q000187:drug effects* / Q000254:growth & development; D011725:Pyridines / Q000494:pharmacology; D011743:Pyrimidines / Q000494:pharmacology; D000077291:Terbinafine; D014230:Triazoles / Q000494:pharmacology; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D009281:Naphthalenes; D009570:Nitriles; D011725:Pyridines; D011743:Pyrimidines; D014230:Triazoles; D017964:Itraconazole; C508735:isavuconazole; C101425:posaconazole; D000666:Amphotericin B; D015725:Fluconazole; D000077336:Caspofungin; D000077291:Terbinafine; D065819:Voriconazole; D000077551:Micafungin