title: Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy.
abstract: We discuss unique features of lens-free computational imaging tools and report some of their emerging results for wide-field on-chip microscopy, such as the achievement of a numerical aperture (NA) of ∼0.8-0.9 across a field of view (FOV) of more than 20 mm(2) or an NA of ∼0.1 across a FOV of ∼18 cm(2), which corresponds to an image with more than 1.5 gigapixels. We also discuss the current challenges that these computational on-chip microscopes face, shedding light on their future directions and applications.
authors.affiliation: Electrical Engineering Department, University of California, Los Angeles, Los Angeles, California, USA.
authors.forename: Alon
authors.initials: A
authors.lastname: Greenbaum
authors.forename: Wei
authors.initials: W
authors.lastname: Luo
authors.forename: Ting-Wei
authors.initials: TW
authors.lastname: Su
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Göröcs
authors.forename: Liang
authors.initials: L
authors.lastname: Xue
authors.forename: Serhan O
authors.initials: SO
authors.lastname: Isikman
authors.forename: Ahmet F
authors.initials: AF
authors.lastname: Coskun
authors.forename: Onur
authors.initials: O
authors.lastname: Mudanyali
authors.forename: Aydogan
authors.initials: A
authors.lastname: Ozcan
mesh_terms: D000465:Algorithms; D004912:Erythrocytes / Q000166:cytology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation* / Q000379:methods*; D007909:Lenses; D008297:Male; D008853:Microscopy / Q000295:instrumentation* / Q000379:methods*; D013094:Spermatozoa / Q000166:cytology