title: Genomic and transcriptomic studies of an RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine)-degrading actinobacterium.
abstract: Whole-genome sequencing, transcriptomic analyses, and metabolic reconstruction were used to investigate Gordonia sp. strain KTR9's ability to catabolize a range of compounds, including explosives and steroids. Aspects of this mycolic acid-containing actinobacterium's catabolic potential were experimentally verified and compared with those of rhodococci and mycobacteria.
authors.affiliation: Department of Microbiology & Immunology, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.
authors.forename: Hao-Ping
authors.initials: HP
authors.lastname: Chen
authors.forename: Song-Hua
authors.initials: SH
authors.lastname: Zhu
authors.forename: Israël
authors.initials: I
authors.lastname: Casabon
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Hallam
authors.forename: Fiona H
authors.initials: FH
authors.lastname: Crocker
authors.forename: William W
authors.initials: WW
authors.lastname: Mohn
authors.forename: Karl J
authors.initials: KJ
authors.lastname: Indest
authors.forename: Lindsay D
authors.initials: LD
authors.lastname: Eltis
mesh_terms: D001483:Base Sequence; D001673:Biodegradation, Environmental; D004269:DNA, Bacterial / Q000032:analysis*; D053834:Explosive Agents / Q000378:metabolism*; D016680:Genome, Bacterial; D033601:Gordonia Bacterium / Q000145:classification / Q000235:genetics* / Q000378:metabolism*; D008969:Molecular Sequence Data; D009159:Mycobacteriaceae / Q000378:metabolism; D012240:Rhodococcus / Q000378:metabolism; D017422:Sequence Analysis, DNA; D059467:Transcriptome; D014227:Triazines / Q000378:metabolism*
chemical_list: D004269:DNA, Bacterial; D053834:Explosive Agents; D014227:Triazines; C009160:cyclonite