title: (1→2) and (1→6)-linked β-D-galactofuranan of microalga Myrmecia biatorellae, symbiotic partner of Lobaria linita.
abstract: A structural study of the cell wall polysaccharides of Myrmecia biatorellae, the symbiotic algal partner of the lichenized fungus Lobaria linita was carried out. It produced a rhamnogalactofuranan, with a (1→6)-β-D-galactofuranose in the main-chain, substituted at O-2 by single units of β-D-Galf, α-L-Rhap or by side chains of 2-O-linked β-D-Galf units. The structure of the polysaccharide was established by chemical and NMR spectroscopic analysis, and is new among natural polysaccharides. Moreover, in a preliminary study, this polysaccharide increased the lethality of mice submitted to polymicrobial sepsis induced by cecal ligation and puncture, probably due to the presence of galactofuranose, which have been shown to be highy immunogenic in mammals.
authors.affiliation: Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Paraná, CP 19.046, CEP 81.531-980, Curitiba, PR, Brazil. lucimaramcc@ufpr.br
authors.forename: Lucimara M C
authors.initials: LM
authors.lastname: Cordeiro
authors.forename: Flávio
authors.initials: F
authors.lastname: Beilke
authors.forename: Franciele Lima
authors.initials: FL
authors.lastname: Bettim
authors.forename: Vanessa de Fátima
authors.initials: Vde F
authors.lastname: Reinhardt
authors.forename: Yanna D
authors.initials: YD
authors.lastname: Rattmann
authors.forename: Marcello
authors.initials: M
authors.lastname: Iacomini
mesh_terms: D000818:Animals; D002473:Cell Wall / Q000737:chemistry*; D008011:Lichens / Q000737:chemistry* / Q000382:microbiology; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D051379:Mice; D058086:Microalgae / Q000737:chemistry*; D008970:Molecular Weight; D011134:Polysaccharides / Q000009:adverse effects / Q000737:chemistry*; D018805:Sepsis / Q000209:etiology* / Q000473:pathology; D013559:Symbiosis / Q000502:physiology*
chemical_list: D011134:Polysaccharides