title: Leiomyosarcoma of the deep femoral vein. A rare cause of venous obstruction in lower limbs and an alternative diagnosis to chronic venous thrombus.
abstract: Primary venous leiomyosarcoma of the extremities is an uncommon, but aggressive, tumoral entity with a high rate of local recurrence and early hematogenous metastasis. In the present article, we report a case of leiomyosarcoma of the vena profunda femoris. This pathology causes deep venous thrombosis-like symptoms. No improvement in lower limb status and a significant and progressive increase in the diameter of the vein as seen using ultrasonography could indicate tumor disease. Particular care must be taken to avoid biopsies due to the possible dissemination. We must complete the medical study with imaging techniques, and the tumor must be removed as soon as possible for histopathological diagnosis. After a follow-up of 12 months, there was no evidence of local or metastatic recurrence in our patient.
authors.affiliation: Servicio de Cirugía Vascular, Complejo Hospitalario de Toledo, Hospital Virgen de la Salud, Toledo, Spain. josepgil22@hotmail.com
authors.forename: Jose
authors.initials: J
authors.lastname: Gil-Sales
authors.forename: Sandra
authors.initials: S
authors.lastname: Vicente
authors.forename: Nuria
authors.initials: N
authors.lastname: Martínez
authors.forename: Manuel
authors.initials: M
authors.lastname: Doblas
authors.forename: Antonio
authors.initials: A
authors.lastname: Orgaz
authors.forename: Angel
authors.initials: A
authors.lastname: Flores
authors.forename: Jose Ignacio
authors.initials: JI
authors.lastname: Leal
authors.forename: Rubén
authors.initials: R
authors.lastname: Rodríguez
authors.forename: Juan
authors.initials: J
authors.lastname: Fontcuberta
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Peinado
mesh_terms: D000368:Aged; D017024:Chemotherapy, Adjuvant; D003251:Constriction, Pathologic; D005268:Femoral Vein / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007890:Leiomyosarcoma / Q000150:complications* / Q000473:pathology / Q000628:therapy; D008297:Male; D010690:Phlebography / Q000379:methods; D011237:Predictive Value of Tests; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler; D014652:Vascular Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D019043:Vascular Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy; D014656:Vascular Surgical Procedures; D020246:Venous Thrombosis / Q000175:diagnosis*