title: The usefulness of a pectoralis major myocutaneous flap in preventing salivary fistulae after salvage total laryngectomy.
abstract: Salvage laryngectomy in patients treated with organ preservation protocols is associated with high rates of postoperative complications. The use of non-irradiated tissue flaps in pharyngeal reconstruction could reduce the incidence of these complications.
  
  
  OBJECTIVE
  This study aims to evaluate the usefulness of the pectoralis major myocutaneous flap in preventing salivary fistulae during the postoperative period of salvage total laryngectomy (TL).
  
  
  METHODS
  This retrospective study enrolled 31 patients operated between April of 2006 and May of 2011. All patients had advanced cancer at the time of the salvage procedure and had been treated with chemoradiotherapy or radiotherapy alone. Pharyngeal reconstruction was performed using pectoralis major myocutaneous flap in 19 cases (61%); primary wound closure occurred in 12 patients (39%).
  
  
  RESULTS
  Salivary fistulae occurred in 16% of the patients who received the flap and in 58% of the patients with primary closure of the pharynx (p < 0.02). No statistically significant differences were noted between the groups with respect to the mean time for fistula formation, reintroduction of an oral diet, or use of a nasoenteric tube for feeding.
  
  
  CONCLUSIONS
  The pectoralis major myocutaneous flap was found to reduce the incidence of salivary fistulae in salvage laryngectomy procedures.
authors.affiliation: Department of Surgery, FM/UFMG.
authors.forename: Alexandre Andrade
authors.initials: AA
authors.lastname: Sousa
authors.forename: Sebastião Maurício de Oliveira
authors.initials: SM
authors.lastname: Castro
authors.forename: José Maria
authors.initials: JM
authors.lastname: Porcaro-Salles
authors.forename: João Marcos Arantes
authors.initials: JM
authors.lastname: Soares
authors.forename: Gustavo Meyer
authors.initials: GM
authors.lastname: de Moraes
authors.forename: Jomar Rezende
authors.initials: JR
authors.lastname: Carvalho
authors.forename: Guilherme Souza
authors.initials: GS
authors.lastname: Silva
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery*; D007825:Laryngectomy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D009367:Neoplasm Staging; D010369:Pectoralis Muscles / Q000637:transplantation*; D012189:Retrospective Studies; D012467:Salivary Gland Fistula / Q000209:etiology / Q000517:prevention & control*; D016879:Salvage Therapy / Q000009:adverse effects / Q000379:methods; D013524:Surgical Flaps