title: Nickel-catalyzed Kumada reaction of tosylalkanes with Grignard reagents to produce alkenes and modified arylketones.
abstract: Open a new door: The first example of alkene synthesis from alkyl electrophiles with Grignard reagents using the Kumada cross-coupling reaction strategy is reported. This method opens a new door for the Kumada cross-coupling reaction, allowing alkenes to be prepared from the reaction of tosylalkanes with Grignard reagents.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
authors.forename: Ji-Cheng
authors.initials: JC
authors.lastname: Wu
authors.forename: Lu-Bing
authors.initials: LB
authors.lastname: Gong
authors.forename: Yuanzhi
authors.initials: Y
authors.lastname: Xia
authors.forename: Ren-Jie
authors.initials: RJ
authors.lastname: Song
authors.forename: Ye-Xiang
authors.initials: YX
authors.lastname: Xie
authors.forename: Jin-Heng
authors.initials: JH
authors.lastname: Li
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D009532:Nickel / Q000737:chemistry*; D014105:Tosyl Compounds / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000475:Alkenes; D007659:Ketones; D014105:Tosyl Compounds; D009532:Nickel