title: Massive localized lymphedema: A case series and literature review.
abstract: A large, deep, soft tissue mass is often malignant in nature; however, a recent study described a large soft tissue mass present in morbidly obese patients that was found to be benign. Massive localized lymphedema (MLL) is a large pedunculated lymphadematous mass found in the lower extremity of morbidly obese patients. MLL often enlarges over many years and may interfere with mobility. Although histologically similar to well-differentiated liposarcoma, MLL has recently emerged as a separate, benign clinical entity. The pathophysiology of MLL is yet to be understood. A literature review, and the authors' experiences are discussed to assist in clinical decision making.
authors.affiliation: Division of Plastic Surgery, Department of Surgery, University of Western Ontario, London, Ontario.
authors.forename: Robin James
authors.initials: RJ
authors.lastname: Evans
authors.forename: Chris
authors.initials: C
authors.lastname: Scilley