title: Diagnostic accuracy of ultra-high-b-value 3.0-T diffusion-weighted MR imaging for detection of prostate cancer.
abstract: OBJECTIVE
  To investigate the diagnostic accuracy of 3.0-T diffusion-weighted imaging (DWI) for detection of prostate cancer by using different b-values.
  
  
  METHODS
  Seventy-three patients underwent magnetic resonance imaging (MRI) at 3.0 T. Three MRI sets were reviewed by two radiologists: MRI and DWI (b = 500 s/mm(2)) (protocol A), MRI and DWI (b = 1000 s/mm(2)) (protocol B), and MRI and DWI (b = 2000s/mm(2)) (protocol C). Areas under the receiver operating characteristic curve (AUCs) were calculated.
  
  
  RESULTS
  The mean of the AUCs in protocol C was larger than those in protocol A and in protocol B (P<.05).
  
  
  CONCLUSIONS
  DWI (b = 2000s/mm(2)) at 3.0 T can improve the diagnostic accuracy for detection of prostate cancer.
authors.affiliation: Department of Radiology, Showa University School of Medicine, Tokyo 142-8555, Japan. yoshimitsu_ohgiya@yahoo.co.jp
authors.forename: Yoshimitsu
authors.initials: Y
authors.lastname: Ohgiya
authors.forename: Jumpei
authors.initials: J
authors.lastname: Suyama
authors.forename: Noritaka
authors.initials: N
authors.lastname: Seino
authors.forename: Takashi
authors.initials: T
authors.lastname: Hashizume
authors.forename: Masaaki
authors.initials: M
authors.lastname: Kawahara
authors.forename: Syouei
authors.initials: S
authors.lastname: Sai
authors.forename: Makoto
authors.initials: M
authors.lastname: Saiki
authors.forename: Jiro
authors.initials: J
authors.lastname: Munechika
authors.forename: Masanori
authors.initials: M
authors.lastname: Hirose
authors.forename: Takehiko
authors.initials: T
authors.lastname: Gokan
mesh_terms: D000368:Aged; D001706:Biopsy; D003937:Diagnosis, Differential; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D006801:Humans; D008297:Male; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology; D012372:ROC Curve; D012189:Retrospective Studies
chemical_list: D017430:Prostate-Specific Antigen