title: Quantitative determination of phenolic compounds in lotus (Nelumbo nucifera) leaves by capillary zone electrophoresis.
abstract: The traditional use of lotus leaves as an anti-inflammatory remedy is associated with the occurrence of phenolic compounds. In this study the first CE method for the analysis of all major phenolic constituents in Nelumbo nucifera leaves is presented. It permits the separation of nine relevant markers in less than 10 min. The optimized procedure was fully validated and then used to analyze diverse samples collected in Vietnam. They revealed significant qualitative and quantitative differences depending on growing area and season. Yet, in all of them, quercetin-3-O-β-D-glucuronide, hyperoside, and isoquercitrin were the most dominant flavonoids.
authors.affiliation: Faculty of Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho City, Vietnam.
authors.forename: Tho Chau Minh Vinh
authors.initials: TC
authors.lastname: Do
authors.forename: Tuan Duc
authors.initials: TD
authors.lastname: Nguyen
authors.forename: Hung
authors.initials: H
authors.lastname: Tran
authors.forename: Hermann
authors.initials: H
authors.lastname: Stuppner
authors.forename: Markus
authors.initials: M
authors.lastname: Ganzera
mesh_terms: D019075:Electrophoresis, Capillary / Q000379:methods* / Q000592:standards; D031653:Nelumbo / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry*; D011794:Quercetin / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D012044:Regression Analysis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014744:Vietnam
chemical_list: D010636:Phenols; C443401:quercetin 3-O-glucuronide; C016527:isoquercitrin; C021304:hyperoside; D011794:Quercetin