title: [The bioresorbable coronary scaffold].
abstract: The routine placement of permanent metal stents has led to an improvement of the long-term and short-term effects of percutaneous coronary interventions. Treatment with the newest generation of drug-eluting stents results in a low risk of restenosis. The antiproliferative drug eluted by these stents, however, prevents endothelialisation; this leads to an increased risk of exposed metallic stent parts, which in turn leads to a higher risk of stent thrombosis. There is evidence that the vessel wall support provided by the stent is only a temporary requirement. Permanent metallic stents could, therefore, be superfluous in the long term. A bioresorbable vascular scaffold (BVS), manufactured from polylactic acid and completely resorbed within 18-24 months, is a new alternative. It is expected that these scaffolds will lead to the disappearance of the risk of late stent thrombosis. Theoretically, the bioresorbable vascular scaffold also provides a considerable advantage for patients who will probably have to undergo further coronary intervention in the future. Metal stents can be an important limiting factor for these patients.
authors.affiliation: Academisch Medisch Centrum, afd. Cardiologie, Amsterdam, the Netherlands.
authors.forename: Mariëlla E C J
authors.initials: ME
authors.lastname: Hassell
authors.forename: Tim P
authors.initials: TP
authors.lastname: van de Hoef
authors.forename: Peter
authors.initials: P
authors.lastname: Damman
authors.forename: Ronak
authors.initials: R
authors.lastname: Delewi
authors.forename: Patrick W
authors.initials: PW
authors.lastname: Serruys
authors.forename: Jan J
authors.initials: JJ
authors.lastname: Piek
mesh_terms: D020341:Absorbable Implants; D015906:Angioplasty, Balloon, Coronary / Q000295:instrumentation* / Q000379:methods; D003324:Coronary Artery Disease / Q000517:prevention & control / Q000628:therapy*; D023921:Coronary Stenosis / Q000517:prevention & control*; D003331:Coronary Vessels / Q000473:pathology; D054855:Drug-Eluting Stents; D006801:Humans; D011474:Prosthesis Design; D015607:Stents; D016896:Treatment Outcome