title: Maternal transmission of borderline personality disorder symptoms in the community-based Greifswald Family Study.
abstract: The authors longitudinally investigated the familial transmission of mothers' BPD symptoms to their offspring, taking maternal depression into consideration. The sample consisted of 323 offspring and their mothers from the community-based Greifswald Family Study. These families were examined for the first time when the children were about 15 years old (T(0)), and again 5 years later (T(1)), using self-ratings and interviews. Regression analyses revealed that maternal BPD symptoms and depression at T(0) were significant predictors of a number of BPD criteria that offspring met at T(1). Furthermore, the analyses also predicted offspring's general psychopathology. In sum, the authors' findings provide evidence for familial aggregation of BPD symptoms and heightened levels of general psychopathology in offspring of mothers with high levels of BPD features, pointing to the need for providing early intervention for this high-risk group.
authors.forename: Sven
authors.initials: S
authors.lastname: Barnow
authors.forename: Maren
authors.initials: M
authors.lastname: Aldinger
authors.forename: Elisabeth A
authors.initials: EA
authors.lastname: Arens
authors.forename: Ines
authors.initials: I
authors.lastname: Ulrich
authors.forename: Carsten
authors.initials: C
authors.lastname: Spitzer
authors.forename: Hans-Jörgen
authors.initials: HJ
authors.lastname: Grabe
authors.forename: Malte
authors.initials: M
authors.lastname: Stopsack
mesh_terms: D000293:Adolescent; D000328:Adult; D001883:Borderline Personality Disorder / Q000175:diagnosis* / Q000523:psychology*; D016241:Child of Impaired Parents / Q000523:psychology* / Q000706:statistics & numerical data; D003863:Depression / Q000175:diagnosis / Q000523:psychology; D005260:Female; D006801:Humans; D007406:Interview, Psychological; D008137:Longitudinal Studies; D008297:Male; D009035:Mothers / Q000523:psychology*; D011237:Predictive Value of Tests; D057566:Self Report