title: [The impact of radiation therapy on sexual function].
abstract: The aim of this study was to evaluate the impact of radiation therapy on sexual life. The analysis was based on a Pubmed literature review. The keywords used for this research were "sexual, radiation, oncology, and cancer". After a brief reminder on the anatomy and physiology, we explained the main complications of radiation oncology and their impact on sexual life. Preventive measures and therapeutic possibilities were discussed. Radiation therapy entails local, systematic and psychological after-effects. For women, vaginal stenosis and dyspareunia represent the most frequent side effects. For men, radiation therapy leads to erectile disorders for 25 to 75% of the patients. These complications have an echo often mattering on the patient quality of life of and on their sexual life post-treatment reconstruction. The knowledge of the indications and the various techniques of irradiation allow reducing its potential sexual morbidity. The information and the education of patients are essential, although often neglected. In conclusion, radiation therapy impacts in variable degrees on the sexual life of the patients. Currently, there are not enough preventive and therapeutic means. Patient information and the early screening of the sexual complications are at stake in the support of patients in the reconstruction of their sexual life.
authors.affiliation: Département universitaire de radiothérapie, centre Oscar-Lambret, Lille, France. thomleroy85@gmail.com
authors.forename: T
authors.initials: T
authors.lastname: Leroy
authors.forename: I
authors.initials: I
authors.lastname: Gabelle Flandin
authors.forename: D
authors.initials: D
authors.lastname: Habold
authors.forename: J-M
authors.initials: JM
authors.lastname: Hannoun-Lévi
mesh_terms: D001284:Atrophy / Q000209:etiology; D002582:Cervix Mucus / Q000528:radiation effects; D003251:Constriction, Pathologic / Q000209:etiology; D005260:Female; D059247:Fertility Preservation; D006801:Humans; D054327:Lubricants / Q000627:therapeutic use; D008297:Male; D009369:Neoplasms / Q000523:psychology / Q000532:radiotherapy; D058986:Phosphodiesterase 5 Inhibitors / Q000627:therapeutic use; D011788:Quality of Life; D011878:Radiotherapy / Q000009:adverse effects*; D012735:Sexual Dysfunction, Physiological / Q000209:etiology* / Q000628:therapy; D020018:Sexual Dysfunctions, Psychological / Q000209:etiology* / Q000628:therapy; D014621:Vagina / Q000473:pathology
chemical_list: D054327:Lubricants; D058986:Phosphodiesterase 5 Inhibitors