title: A new antifeedant clerodane diterpenoid from Tinospora cordifolia.
abstract: Phytochemical investigation of the chloroform extract of Tinospora cordifolia yielded a new clerodane diterpenoid tincordin along with tinosporide, 8-hydroxytinosporide, columbin, 8-hydroxycolumbin and 10-hydroxycolumbin. The structure of the new compound was elucidated comprehensively using 1D and 2D NMR methods. All major clerodane diterpenoids isolated were tested for their efficacy as insect antifeedants against Earias vitella, Plutella xylostella and Spodoptera litura.
authors.affiliation: a Department of Chemistry , School of Chemical and Biotechnology, SASTRA University , Thanjavur 613401 , Tamil Nadu , India.
authors.forename: Aravind
authors.initials: A
authors.lastname: Sivasubramanian
authors.forename: Krishna Kumari
authors.initials: KK
authors.lastname: Gadepalli Narasimha
authors.forename: Rishikesan
authors.initials: R
authors.lastname: Rathnasamy
authors.forename: Ana M F Oliveira
authors.initials: AM
authors.lastname: Campos
mesh_terms: D000818:Animals; D004224:Diterpenes / Q000737:chemistry / Q000494:pharmacology; D045785:Diterpenes, Clerodane / Q000737:chemistry* / Q000494:pharmacology*; D007313:Insecta / Q000187:drug effects; D007783:Lactones / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D018411:Spodoptera / Q000187:drug effects; D031610:Tinospora / Q000737:chemistry*
chemical_list: D004224:Diterpenes; D045785:Diterpenes, Clerodane; D007783:Lactones; C062507:tinosporide