title: Genome sequence of a Neisseria meningitidis capsule null locus strain from the clonal complex of sequence type 198.
abstract: Neisseria meningitidis is a commensal and accidental pathogen exclusively of humans. Although the production of polysaccharide capsules is considered to be essential for meningococcal virulence, there have been reports of constitutively unencapsulated strains causing invasive meningococcal disease (IMD). Here we report the genome sequence of a capsule null locus (cnl) strain of sequence type 198 (ST-198), which is found in half of the reported cases of IMD caused by cnl meningococcal strains.
authors.affiliation: Institute for Hygiene and Microbiology, University of Würzburg, Würzburg, Germany.
authors.forename: Sabine
authors.initials: S
authors.lastname: Schork
authors.forename: Andreas
authors.initials: A
authors.lastname: Schlüter
authors.forename: Jochen
authors.initials: J
authors.lastname: Blom
authors.forename: Susanne
authors.initials: S
authors.lastname: Schneiker-Bekel
authors.forename: Alfred
authors.initials: A
authors.lastname: Pühler
authors.forename: Alexander
authors.initials: A
authors.lastname: Goesmann
authors.forename: Matthias
authors.initials: M
authors.lastname: Frosch
authors.forename: Christoph
authors.initials: C
authors.lastname: Schoen
mesh_terms: D016667:Bacterial Capsules / Q000235:genetics; D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics*; D016680:Genome, Bacterial; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D058889:Molecular Typing; D009345:Neisseria meningitidis / Q000235:genetics* / Q000302:isolation & purification; D017422:Sequence Analysis, DNA
chemical_list: D004269:DNA, Bacterial