title: A framework for elimination of perinatal transmission of HIV in the United States.
abstract: The availability of effective interventions to prevent mother-to-child HIV transmission and the significant reduction in the number of HIV-infected infants in the United States have led to the concept that elimination of mother-to-child HIV transmission (EMCT) is possible. Goals for elimination are presented. We also present a framework by which elimination efforts can be coordinated, beginning with comprehensive reproductive health care (including HIV testing) and real-time case-finding of pregnancies in HIV-infected women, and conducted through the following: facilitation of comprehensive clinical care and social services for women and infants; case review and community action; allowing continuous quality research in prevention and long-term follow-up of HIV-exposed infants; and thorough data reporting for HIV surveillance and EMCT evaluation. It is emphasized that EMCT will not be a one-time accomplishment but, rather, will require sustained effort as long as there are new HIV infections in women of childbearing age.
authors.affiliation: Centers for Disease Control and Prevention, MS E-45, 1600 Clifton Rd, Atlanta, GA 30333, USA. sxn9@cdc.gov
authors.forename: Steven
authors.initials: S
authors.lastname: Nesheim
authors.forename: Allan
authors.initials: A
authors.lastname: Taylor
authors.forename: Margaret A
authors.initials: MA
authors.lastname: Lampe
authors.forename: Peter H
authors.initials: PH
authors.lastname: Kilmarx
authors.forename: Lauren
authors.initials: L
authors.lastname: Fitz Harris
authors.forename: Suzanne
authors.initials: S
authors.lastname: Whitmore
authors.forename: Judy
authors.initials: J
authors.lastname: Griffith
authors.forename: Melissa
authors.initials: M
authors.lastname: Thomas-Proctor
authors.forename: Kevin
authors.initials: K
authors.lastname: Fenton
authors.forename: Jonathan
authors.initials: J
authors.lastname: Mermin
mesh_terms: D002487:Centers for Disease Control and Prevention, U.S.; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000517:prevention & control / Q000635:transmission*; D006291:Health Policy; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D008427:Maternal Health Services / Q000379:methods / Q000458:organization & administration*; D018743:Perinatal Care / Q000379:methods / Q000458:organization & administration; D011247:Pregnancy; D062486:Public Health Surveillance; D014481:United States