title: Effects of exercise on S-IGA and URS in postmenopausal women.
abstract: 32 postmenopausal women were randomized to a 16-week home-based walking program or control group. Before and after the intervention, each subject completed a graded maximal treadmill test to establish VO(2)max and resting saliva was collected to determine levels of salivary immunoglobulin A. The 16-week walking program resulted in an increase in VO(2)max (+10.4%; p<0.01). Repeated measures ANOVA revealed a marked increase in the resting secretion rate of salivary immunoglobulin A (+37.4%; p<0.05) in the exercise group following training. Independent of study group, both before and after the intervention, the secretion rate of salivary immunoglobulin A ( - 32.3%) and saliva flow rate (- 29.3%) were reduced following acute maximal exercise (p<0.05). Weekly upper respiratory symptomatology logs revealed that the number of incidences of upper respiratory symptoms throughout the intervention period were the same and the duration per incidence (control: 5.3±1.5 days; exercise: 6.3±2.2 days) were similar between study groups. These findings in postmenopausal women support that the secretion rate of salivary immunoglobulin A and saliva flow rate are reduced immediately following maximal exercise. Moreover, a 16-week moderate intense walking program can increase the secretion of salivary immunoglobulin A without affecting upper respiratory symptomatology.
authors.affiliation: Health and Physical Education, Henry Ford Community College, Dearborn, USA. csloan@hfcc.edu
authors.forename: C A
authors.initials: CA
authors.lastname: Sloan
authors.forename: H J
authors.initials: HJ
authors.lastname: Engels
authors.forename: M M
authors.initials: MM
authors.lastname: Fahlman
authors.forename: H E
authors.initials: HE
authors.lastname: Yarandi
authors.forename: J E
authors.initials: JE
authors.lastname: Davis
mesh_terms: D000704:Analysis of Variance; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005260:Female; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000378:metabolism*; D015994:Incidence; D008875:Middle Aged; D010100:Oxygen / Q000378:metabolism; D017698:Postmenopause; D012141:Respiratory Tract Infections / Q000453:epidemiology; D012463:Saliva / Q000276:immunology*; D013997:Time Factors; D016138:Walking / Q000502:physiology
chemical_list: D007071:Immunoglobulin A, Secretory; D010100:Oxygen