title: Biophysical evaluation of radiofrequency electromagnetic field effects on male reproductive pattern.
abstract: There are possible hazardous health effects of exposure to radiofrequency electromagnetic radiations emitted from mobile phone on the human reproductive pattern. It is more effective while keeping mobile phones in pocket or near testicular organs. Present review examines the possible concern on radio frequency radiation interaction and biological effects such as enzyme induction, and toxicological effects, including genotoxicity and carcinogenicity, testicular cancer, and reproductive outcomes. Testicular infertility or testicular cancer due to mobile phone or microwave radiations suggests an increased level of reactive oxygen species (ROS). Though generation of ROS in testis has been responsible for possible toxic effects on physiology of reproduction, the reviews of last few decades have well established that these radiations are very harmful and cause mutagenic changes in reproductive pattern and leads to infertility. The debate will be focused on bio-interaction mechanism between mobile phone and testicular cancer due to ROS formation. This causes the biological damage and leads to several changes like decreased sperm count, enzymatic and hormonal changes, DNA damage, and apoptosis formation. In the present review, physics of mobile phone including future research on various aspects has been discussed.
authors.affiliation: School of Environmental Sciences, Jawaharlal Nehru University, New Delhi, India. kavindra_biotech@yahoo.co.in
authors.forename: Kavindra Kumar
authors.initials: KK
authors.lastname: Kesari
authors.forename: Sanjay
authors.initials: S
authors.lastname: Kumar
authors.forename: Jayprakash
authors.initials: J
authors.lastname: Nirala
authors.forename: Mohd Haris
authors.initials: MH
authors.lastname: Siddiqui
authors.forename: Jitendra
authors.initials: J
authors.lastname: Behari
mesh_terms: D040421:Cell Phone; D004574:Electromagnetic Fields / Q000009:adverse effects*; D006801:Humans; D007248:Infertility, Male / Q000209:etiology / Q000235:genetics; D008297:Male; D016296:Mutagenesis / Q000528:radiation effects; D011846:Radio Waves / Q000009:adverse effects*; D017382:Reactive Oxygen Species / Q000378:metabolism / Q000528:radiation effects; D012098:Reproduction / Q000235:genetics / Q000528:radiation effects*; D013737:Testis / Q000378:metabolism / Q000528:radiation effects
chemical_list: D017382:Reactive Oxygen Species