title: [The efficacy and safety of subcutaneous immuno-therapy with dermatophagoides pteronyssinus for allergic rhinitis].
abstract: OBJECTIVE
  To evaluate the efficacy and safety of subcutaneous immunotherapy with a standardized Dermatophagoides pteronyssinus extract for allergic rhinitis.
  
  
  METHODS
  Sixty-eight patients with allergic rhinitis who received specific immunotherapy with a standardized dermatophagoides pteronyssinus extract were enrolled in this study. The clinical symptoms and signs were scored before and 2 years after treatment. Side effects were registered. Symptom and side effect scores were assessed to evaluate the clinical efficacy and safety.
  
  
  RESULTS
  There was a significant difference (P < 0.01) in symptom and medication scores between the two groups tow years after treatment. The patients had fewer symptoms and lower intake of medication. No severe systemic reactions were registered.
  
  
  CONCLUSIONS
  Immunotherapy with a standardized dermatophagoides pteronyssinus extract is effective and safe to treat patients clinically sensitive to this allergen.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Central Hospital of Enshi, Enshi, 445000, China. dalia00589@163.com
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.forename: Jing
authors.initials: J
authors.lastname: Wan
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhou
authors.forename: Zhong
authors.initials: Z
authors.lastname: Liu
mesh_terms: D000485:Allergens / Q000627:therapeutic use*; D000818:Animals; D040002:Dermatophagoides pteronyssinus / Q000276:immunology*; D005260:Female; D006801:Humans; D007167:Immunotherapy / Q000379:methods*; D008297:Male; D065631:Rhinitis, Allergic / Q000628:therapy*
chemical_list: D000485:Allergens