title: Atypical transformation in sacral drop metastasis from posterior fossa choroid plexus papilloma.
abstract: Choroid plexus papillomas (CPP) are rare tumours and spinal metastases of CPP are even less common. We report a 50-year-old woman with spinal drop metastases at Th9 and S1-2 6 years after total resection of a posterior fossa CPP. The metastasis at S1-2 was resected and histological examination showed transformation to an atypical CPP. Atypical transformation in a metastasis years after resection of a benign posterior fossa CPP has been described once. We would like to advocate craniospinal MRI at the time of initial diagnosis as well as periodic follow-up after total and subtotal resection of a posterior fossa CPP in adults at least once in 1 or 2 years, depending on the histological grading of the primary CPP. In our case report, this could have resulted in earlier diagnosis of the locoregional recurrence or of the spinal drop metastasis.
authors.affiliation: Department of Neurology, St Elisabeth Hospital, Tilburg, The Netherlands. m.stuivenvolt@elisabeth.nl
authors.forename: Mischa
authors.initials: M
authors.lastname: Stuivenvolt
authors.forename: Ellen
authors.initials: E
authors.lastname: Mandl
authors.forename: Jeroen
authors.initials: J
authors.lastname: Verheul
authors.forename: Ruth
authors.initials: R
authors.lastname: Fleischeuer
authors.forename: Cees C
authors.initials: CC
authors.lastname: Tijssen
mesh_terms: D003399:Craniotomy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000532:radiotherapy*; D020288:Papilloma, Choroid Plexus / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D012447:Sacrum / Q000473:pathology*; D013125:Spinal Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000556:secondary