title: Molecular AND logic gate based on bacterial anaerobic respiration.
abstract: Enzyme coding genes that integrate information for anaerobic respiration in Shewanella oneidensis MR-1 were used as input for constructing an AND logic gate. The absence of one or both genes inhibited electrochemically-controlled anaerobic respiration, while wild type bacteria were capable of accepting electrons from an electrode for DMSO reduction.
authors.affiliation: Department of Civil Engineering and Mechanics, University of Wisconsin-Milwaukee, Milwaukee, WI 53211, USA.
authors.forename: Mary Anitha
authors.initials: MA
authors.lastname: Arugula
authors.forename: Namita
authors.initials: N
authors.lastname: Shroff
authors.forename: Evgeny
authors.initials: E
authors.lastname: Katz
authors.forename: Zhen
authors.initials: Z
authors.lastname: He
mesh_terms: D000693:Anaerobiosis; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D000242:Cyclic AMP / Q000096:biosynthesis / Q000378:metabolism; D002373:Cyclic AMP Receptor Protein / Q000378:metabolism; D004121:Dimethyl Sulfoxide / Q000378:metabolism; D055664:Electrochemical Techniques; D004566:Electrodes; D004583:Electrons; D007506:Iron-Sulfur Proteins / Q000235:genetics / Q000378:metabolism*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000235:genetics / Q000378:metabolism*; D020592:Shewanella / Q000201:enzymology / Q000235:genetics / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D002373:Cyclic AMP Receptor Protein; D007506:Iron-Sulfur Proteins; D000242:Cyclic AMP; D010088:Oxidoreductases; C045664:dimethyl sulfoxide reductase; D004121:Dimethyl Sulfoxide