title: [The study on AHI, LSaO2 and ET-1 in patients with obstructive sleep apnea-hypopnea syndrome after H-UPPP].
abstract: OBJECTIVE
  To explore the treatment effect of H-UPPP on patients with obstructive sleep apnea hypopnea syndrome (OSAHS).
  
  
  METHODS
  Seventy-nine patients were enrolled in our study. Among which 49 patients were done with H-UPPP, and the other 30 patients were done with UPPP. AHI and LSaO2 were monitored by polysomnography and plasma endothelins-1 were tested with enzyme linked immunosorbent assay (ELISA) before and after operation.
  
  
  RESULTS
  Forty-one patients were improved with reduced snoring and daytime sleepiness one year after operation in H-UPPP group,and the overall efficiency was 83.7%. Twenty-six patients were improved with reduced snoring and daytime sleepiness one year after operation in UPPP group, and the overall efficiency was 86.7%. There were significant differences of AHI, LSaO2 and ET-1 before and after operation between the two groups. Negative correlation was showed between AHI and LSaO2, also between LSaO2 and ET-1.
  
  
  CONCLUSIONS
  Both H-UPPP and UPPP were proved to be effective to patients with OSAHS. The perioperative complications with H-UPPP was less than UPPP.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Yongchuan Hospital, Chongqing Medical University, Chongqing, 402160, China. wxsent2000@yahoo.com.cn
authors.forename: Xiaosong
authors.initials: X
authors.lastname: Wu
authors.forename: Yi
authors.initials: Y
authors.lastname: Yu
authors.forename: Dongli
authors.initials: D
authors.lastname: Hu
mesh_terms: D000328:Adult; D001049:Apnea / Q000097:blood / Q000601:surgery; D006970:Disorders of Excessive Somnolence / Q000097:blood / Q000601:surgery*; D019332:Endothelin-1 / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010160:Palate, Soft / Q000601:surgery; D010614:Pharynx / Q000601:surgery; D017286:Polysomnography; D020181:Sleep Apnea, Obstructive / Q000097:blood / Q000601:surgery*; D012894:Sleep Stages; D012913:Snoring / Q000097:blood / Q000601:surgery*; D014609:Uvula / Q000601:surgery
chemical_list: D019332:Endothelin-1