title: [Standards of microbiological diagnostics of spondylodiscitis].
abstract: In most cases spondylodiscitis is due to a monomicrobial infection caused by hematogenous dissemination of Staphylococcus aureus. There are, however, many other possible pathogens causing spondylodiscitis and the pathogen responsible can only be identified in approximately 50% of cases. This leads to delayed diagnosis and therapy and an increased morbidity and mortality rate. Failures in planning and performing material recovery are often the reason. As pathogen-specific antimicrobial treatment according to the results of susceptibility testing is the main component of interdisciplinary therapy, all available methods for identification of the pathogen, such as blood cultures, intraoperative and computed tomography (CT) guided biopsies of inflammatory fluids and tissues as well as molecular biological methods should be performed to optimize antimicrobial therapy.
authors.affiliation: Department Orthopädie, Unfallchirurgie und Paraplegiologie, Sektion septische Orthopädie, Stiftung Orthopädische Universitätsklinik Heidelberg, Schlierbacher Landstr. 200a, 69118, Heidelberg, Deutschland. burkhard.lehner@med.uni-heidelberg.de
authors.forename: B
authors.initials: B
authors.lastname: Lehner
authors.forename: M
authors.initials: M
authors.lastname: Akbar
authors.forename: C
authors.initials: C
authors.lastname: Rehnitz
authors.forename: G W
authors.initials: GW
authors.lastname: Omlor
authors.forename: U
authors.initials: U
authors.lastname: Dapunt
authors.forename: I
authors.initials: I
authors.lastname: Burckhardt
mesh_terms: D001424:Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology*; D001431:Bacteriological Techniques / Q000592:standards*; D015299:Discitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D005858:Germany; D006801:Humans; D017410:Practice Guidelines as Topic