title: Purple glove syndrome: a dreadful complication of intravenous phenytoin administration.
abstract: Purple glove syndrome is an uncommon but dreaded complication of intravenous phenytoin administration characterised by pain, oedema and purple-blue discolouration of the limb distal to the site of injection. We describe a 37-year-old gentleman having the characteristic purple glove appearance after phenytoin loading, and discuss the salient features of this syndrome highlighting the pathophysiological and preventive aspects.
authors.affiliation: Department of Neurology, Chhatrapati Shahuji Maharaj Medical University, Lucknow, Uttar Pradesh, India.
authors.forename: Rakesh
authors.initials: R
authors.lastname: Lalla
authors.forename: Hardeep Singh
authors.initials: HS
authors.lastname: Malhotra
authors.forename: Ravindra Kumar
authors.initials: RK
authors.lastname: Garg
authors.forename: Ritesh
authors.initials: R
authors.lastname: Sahu
mesh_terms: D061605:Administration, Intravenous; D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology; D004487:Edema / Q000139:chemically induced*; D004660:Encephalitis / Q000150:complications; D017809:Fatal Outcome; D006225:Hand; D006801:Humans; D008297:Male; D010146:Pain / Q000139:chemically induced*; D010672:Phenytoin / Q000008:administration & dosage / Q000009:adverse effects*; D010859:Pigmentation Disorders / Q000139:chemically induced*; D012640:Seizures / Q000188:drug therapy / Q000209:etiology; D013577:Syndrome
chemical_list: D000927:Anticonvulsants; D010672:Phenytoin