title: Adult Langerhans cell histiocytosis in a middle aged Ethiopian woman.
abstract: Langerhans' cell histiocytosis represents a diverse group of rare disorders characterized by proliferation and infiltration of various organs by bone marrow-derived abnormal Langerhans' cells. These diorders exhibit varied patterns of organ involvement, age distribution, prognosis and clinical manifestation. Here in we discuss an adult presentation of the disease in a 43 years old lady and summarize the latest recommendations regarding the classification, pathogenesis, work up and treatment of adult patients with these disorders.
authors.affiliation: Department of Dermatology/Venereology, Addis Ababa University School of Medicine, P.O.BOX 9086,Addis Ababa, Ethiopia.
authors.forename: Munir H
authors.initials: MH
authors.lastname: Idriss
authors.forename: Fuad
authors.initials: F
authors.lastname: Temam
authors.forename: Mihretu
authors.initials: M
authors.lastname: Woldeyes
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D001706:Biopsy; D005002:Ethiopia; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007801:Langerhans Cells / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use; D016896:Treatment Outcome; D014747:Vinblastine / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D000972:Antineoplastic Agents, Phytogenic; D014747:Vinblastine; D011239:Prednisolone