title: [Cellularity and extracellularity: the multi-fibrillar system: from cytoskeleton to connective tissue].
abstract: This brief text aims at illustrating the interactions between connective tissue fibers and cell cytoskeleton fibers. These two networks are connected by molecular bridges at the level of the cell membrane of the cells of the connective and vascular tissues, allowing functional adjustments across the two domains, but also the transduction of forces and tensions into a biochemical alphabet. The signaling between the cell kern and its environment, but equally the other way round, from the environment to the core of the cell, depends on it.
authors.affiliation: Université Paris Sud 11 & Biopark Campus Cancer, 1, mail Pr Georges Mathé, 94807 Villejuif, France. patrizia.d-alessio@inserm.fr
authors.forename: P A
authors.initials: PA
authors.lastname: d'Alessio
mesh_terms: D003599:Cytoskeleton / Q000502:physiology*; D005109:Extracellular Matrix / Q000502:physiology*; D006801:Humans; D020894:Microfibrils / Q000502:physiology*