title: The role of manganese in etiopathogenesis and prevention of selected diseases.
abstract: Manganese (Mn) is an essential trace element, necessary for development and growth of the organism. The adequate content of this element in the body determines proper metabolism of amino acids, cholesterol and carbohydrates. This mineral influences activity of several enzymes involved in metabolic and redox processes. Mn absorption and retention disturbances may participate in etiopathogenesis of some diseases and disorders. This article is a review of knowledge about the role of Mn in etiopathogenesis and prevention of selected diseases: brain disorders, diabetes, lipid disturbances and cancers.
authors.affiliation: Chair and Department of Food Science and Dietetics, Wrocław Medical University, Wrocław. katarzynazablocka0112@gmail.com
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Zabłocka-Słowińska
authors.forename: Halina
authors.initials: H
authors.lastname: Grajeta
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D001927:Brain Diseases / Q000378:metabolism* / Q000517:prevention & control; D002784:Cholesterol / Q000378:metabolism; D003920:Diabetes Mellitus / Q000378:metabolism* / Q000517:prevention & control; D006801:Humans; D050356:Lipid Metabolism; D008064:Lipidoses / Q000378:metabolism* / Q000517:prevention & control; D008345:Manganese / Q000378:metabolism* / Q000493:pharmacokinetics; D009369:Neoplasms / Q000378:metabolism* / Q000517:prevention & control; D009422:Nervous System Diseases / Q000378:metabolism* / Q000517:prevention & control; D010084:Oxidation-Reduction; D014131:Trace Elements / Q000378:metabolism
chemical_list: D000596:Amino Acids; D014131:Trace Elements; D008345:Manganese; D002784:Cholesterol