title: Current technology in the diagnosis of developmentally related lung disorders.
abstract: Respiratory disorders that present in the newborn period may result from structural, functional, or acquired mechanisms that limit gas exchange between the airspace and vascular bed. Exciting new imaging, gene sequencing, mass spectrometry, and molecular and cell-based techniques are enhancing our understanding of mechanisms of disease; highlighting the complexity of interactions between genes, development, and environment in the manifestation of health and disease; and becoming part of the clinical armamentarium for the care of patients. Some of these technologies and their clinical potential are briefly reviewed in this paper.
authors.affiliation: Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine, St Louis, Mo 63110, USA.
authors.forename: Aaron
authors.initials: A
authors.lastname: Hamvas
mesh_terms: D002648:Child; D003952:Diagnostic Imaging / Q000379:methods* / Q000639:trends; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000002:abnormalities* / Q000196:embryology / Q000254:growth & development / Q000502:physiology; D008171:Lung Diseases / Q000175:diagnosis* / Q000209:etiology*; D015619:Respiratory System Abnormalities / Q000150:complications* / Q000175:diagnosis