title: [Catheter-directed thrombolysis in iliofemoral deep-vein thrombosis].
abstract: Despite optimal treatment of acute deep-vein thrombosis (DVT) there is a great chance of recurrent DVT and development of post-thrombotic syndrome (PTS) in the long term. The degree of spontaneous recanalization differs per patient and per thrombus location. 90% of all femoropopliteal occlusions will fully recanalize within 1 year; however, in the case of an iliofemoral thrombosis, recanalization occurs only in a minority of cases. Post-thrombotic complications occur more often following iliofemoral thrombosis, and the chance of recurrent thrombosis is greater than following thrombosis in a more distal location. An anatomical variation or abnormality also more often underlies an iliofemoral thrombosis. It is important to identify patients with a greater chance of developing PTS promptly and to treat them in order to prevent post-thrombotic damage. There are still insufficient trial data available to implement catheter-directed thrombolysis as standard therapy for iliofemoral thrombosis
authors.affiliation: Afd. Vaatchirurgie en CARIM, Maastricht Universitair Medisch Centrum, Maastricht, the Netherlands. R.Strijkers@maastrichtuniversity.nl
authors.forename: Rob H W
authors.initials: RH
authors.lastname: Strijkers
authors.forename: Arina J
authors.initials: AJ
authors.lastname: ten Cate-Hoek
authors.forename: Jochen
authors.initials: J
authors.lastname: Grommes
authors.forename: Carsten  W K P
authors.initials: C
authors.lastname: Arnoldussen
authors.forename: Cees H A
authors.initials: CH
authors.lastname: Wittens
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D002406:Catheterization, Peripheral; D005268:Femoral Vein; D006801:Humans; D007084:Iliac Vein; D054070:Postthrombotic Syndrome / Q000209:etiology / Q000517:prevention & control; D015912:Thrombolytic Therapy / Q000379:methods*; D016896:Treatment Outcome; D020246:Venous Thrombosis / Q000628:therapy*
chemical_list: D000925:Anticoagulants