title: Ultrasensitive photoelectrochemical sensing of nicotinamide adenine dinucleotide based on graphene-TiO2 nanohybrids under visible irradiation.
abstract: In this paper, the photoelectrochemical behavior of graphene-TiO(2) (G-TiO(2)) nanohybrids was investigated in the visible region and a new photoelectrochemical sensor for sensitive determination of nicotinamide adenine dinucleotide (NADH) was proposed. Under visible light, the G-TiO(2) nanohybrids possessed enhanced photocurrent, which was nearly 5 times than that of pure TiO(2) nanocrystals (NCs). Based on the enhanced photocurrent of G-TiO(2) nanohybrids toward NADH, a new photoelectrochemical methodology for ultrasensitive determination of NADH was developed. The proposed sensor showed linearly enhanced photocurrent by increasing the NADH concentration from 1.0×10(-8) to 2.0×10(-3) M with a low detection limit of 3.0×10(-9) M. Furthermore, this sensor exhibited good selectivity and stability towards NADH determination. This strategy opens up a new avenue for the application of graphene-based hybrids in the field of photoelectrochemical sensing and monitoring.
authors.affiliation: Key Laboratory of Modern Agriculture Equipment and Technology, School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, PR China. wangkun@ujs.edu.cn
authors.forename: Kun
authors.initials: K
authors.lastname: Wang
authors.forename: Jun
authors.initials: J
authors.lastname: Wu
authors.forename: Qian
authors.initials: Q
authors.lastname: Liu
authors.forename: Yicong
authors.initials: Y
authors.lastname: Jin
authors.forename: Jiajia
authors.initials: J
authors.lastname: Yan
authors.forename: Jianrong
authors.initials: J
authors.lastname: Cai
mesh_terms: D055664:Electrochemical Techniques; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D057230:Limit of Detection; D009243:NAD / Q000097:blood*; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D055668:Photochemical Processes; D012680:Sensitivity and Specificity; D014025:Titanium / Q000737:chemistry*
chemical_list: D009243:NAD; C009495:titanium dioxide; D006108:Graphite; D014025:Titanium