title: Effect of a single-piece and a three-piece acrylic sharp-edged IOL on posterior capsule opacification.
abstract: BACKGROUND
  To compare the intensity of posterior capsule opacification (PCO) between two intraocular lenses (IOLs) of the same optic material, but with different haptic design (1-piece vs. 3-piece).
  
  
  METHODS
  This prospective intraindividual controlled cohort study comprised eighty eyes of 40 patients with bilateral age-related cataract. Each patient received a Polylens Y10 (Polytech, Germany) 1-piece IOL in 1 eye and a Polylens Y30 (Polytech, Germany) 3-piece IOL in the contralateral eye. The IOL type in the first operated eye was randomly assigned before patient recruitment. Digital slitlamp photographs were taken 1 year postoperatively using a standardized photographic technique for regeneratory PCO. The amount of PCO was assessed subjectively at the slitlamp and objectively using automated image-analysis software.
  
  
  RESULTS
  The Polylens Y10 (1-piece) group showed significantly higher regeneratory and fibrotic PCO scores 1 year after surgery in subjective slitlamp evaluation, however not with objective evaluation using automated image-analysis software. Subjective PCO assessment resulted in a mean PCO score (scale = 0-10) of 1.6 in the Polylens Y10 group and 0.6 in the Polylens Y30 group at 1 year (p < 0.05). The mean automated image-analysis software PCO score was 1.5 in the Polylens Y10 group and 0.9 in the Polylens Y30 group (p = 0.6).
  
  
  CONCLUSIONS
  Both investigated IOLs showed good clinical performance regarding PCO, BCVA and IOL-centration. The Polylens Y10 IOL showed slightly more regeneratory PCO than the 3-piece acrylic IOL 1 year after surgery.
authors.affiliation: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
authors.forename: Georgios
authors.initials: G
authors.lastname: Mylonas
authors.forename: Martin
authors.initials: M
authors.lastname: Prskavec
authors.forename: Ramin
authors.initials: R
authors.lastname: Baradaran-Dilmaghani
authors.forename: Nadja
authors.initials: N
authors.lastname: Karnik
authors.forename: Wolf
authors.initials: W
authors.lastname: Buehl
authors.forename: Matthias
authors.initials: M
authors.lastname: Wirtitsch
mesh_terms: D000179:Acrylates; D000368:Aged; D002386:Cataract / Q000503:physiopathology*; D002387:Cataract Extraction; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D007910:Lenses, Intraocular; D008297:Male; D057852:Posterior Capsule of the Lens / Q000473:pathology*; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D011474:Prosthesis Design; D016896:Treatment Outcome; D014792:Visual Acuity
chemical_list: D000179:Acrylates