title: Synthesis, structure and insecticidal activities of some novel amides containing N-pyridylpyrazole moeities.
abstract: In our search for environmentally benign insecticides with high activity, low toxicity and low residue, a novel series of amides containing N- pyridylpyrazole moieties were designed and synthesized. The structures of the title compounds were characterized and confirmed by 1H-NMR and elemental analysis. Furthermore, the structure of compound 7l was determined by single crystal X-ray diffraction. The preliminary bioassay tests showed that some of them exhibited good insecticidal activities against Mythimna separata Walker, Plutella xylostella (Linnaeus, 1758) and Laphygma exigua Hübner.
authors.affiliation: Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, China. wldong33@163.com
authors.forename: Wei-Li
authors.initials: WL
authors.lastname: Dong
authors.forename: Jing-Ying
authors.initials: JY
authors.lastname: Xu
authors.forename: Li-Xia
authors.initials: LX
authors.lastname: Xiong
authors.forename: Zheng-Ming
authors.initials: ZM
authors.lastname: Li
mesh_terms: D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry*; D000818:Animals; D015195:Drug Design; D007306:Insecticides / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D009036:Moths; D011720:Pyrazoles / Q000032:analysis* / Q000737:chemistry; D013329:Structure-Activity Relationship
chemical_list: D000577:Amides; D007306:Insecticides; D011720:Pyrazoles