title: Vitamin B₁₂ deficiency: an unusual cause for recurrent generalised seizures with pancytopaenia.
abstract: We report the case of a 70-year-old man with pancytopaenia and new-onset recurrent generalised seizures. Detailed evaluation yielded a diagnosis of vitamin B(12) deficiency. He was treated with parenteral vitamin B(12) supplementation and antiepileptic drugs. Seizures are an unusual manifestation of vitamin B(12) deficiency and possible mechanisms of epileptogenesis are discussed.
authors.affiliation: Department of Medicine, Kasturba Medical College, Manipal, Karnataka, India.
authors.forename: Kushal
authors.initials: K
authors.lastname: Naha
authors.forename: Sowjanya
authors.initials: S
authors.lastname: Dasari
authors.forename: G
authors.initials: G
authors.lastname: Vivek
authors.forename: Mukhyaprana
authors.initials: M
authors.lastname: Prabhu
mesh_terms: D000368:Aged; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects; D002552:Cerebral Ventricles / Q000473:pathology; D003937:Diagnosis, Differential; D057915:Drug Substitution; D004829:Epilepsy, Generalized / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D007262:Infusions, Intravenous; D056784:Leukoencephalopathies / Q000188:drug therapy / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination; D010198:Pancytopenia / Q000188:drug therapy / Q000209:etiology*; D010672:Phenytoin / Q000008:administration & dosage / Q000009:adverse effects; D012008:Recurrence; D014805:Vitamin B 12 / Q000008:administration & dosage; D014806:Vitamin B 12 Deficiency / Q000139:chemically induced / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
chemical_list: D000927:Anticonvulsants; D010672:Phenytoin; D014805:Vitamin B 12