title: Preparation and characterization of novel oxidized cellulose acetate methyl esters.
abstract: In this paper, we report the preparation of oxidized cellulose acetate methyl esters (OCAM) from OCA (OC14A: carboxylic acid content 10.6% (w/w), degree of acetyl group substitution: 1.89; OC21A: carboxylic acid content 15.7% (w/w), degree of acetyl group substitution: 1.70) by treatment with methanol at room temperature using 4-dimethylaminopyridine (DMAP) as a catalyst and dicyclohexylcarbodiimide (DCC) as a coupling agent. The new polymers were characterized by Fourier-transform infrared (FT-IR) and (1)H and (13)C nuclear magnetic resonance spectroscopies, carboxylic acid content determination, moisture sorption isotherms, intrinsic viscosity, and powder X-ray diffractometry. The new polymers are amorphous powders. It is practically insoluble in water but show solubility in a range of organic solvents.
authors.affiliation: Department of Pharmaceutical and Analytical Development, Novartis Pharmaceuticals, One Health Plaza, East Hanover, NJ 07936, USA. dong.yang01@gmail.com
authors.forename: D
authors.initials: D
authors.lastname: Yang
authors.forename: V
authors.initials: V
authors.lastname: Kumar
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry; D002384:Catalysis; D002482:Cellulose / Q000031:analogs & derivatives* / Q000737:chemistry; D002483:Cellulose, Oxidized / Q000737:chemistry*; D004952:Esters / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D011108:Polymers / Q000737:chemistry*; D012995:Solubility; D012997:Solvents; D017550:Spectroscopy, Fourier Transform Infrared; D014783:Viscosity; D014867:Water / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D002264:Carboxylic Acids; D002483:Cellulose, Oxidized; D004952:Esters; D011108:Polymers; D012997:Solvents; D014867:Water; C005062:acetylcellulose; D002482:Cellulose