title: Chromosomal translocations among the healthy human population: implications in oncogenesis.
abstract: Chromosomal translocations are characteristic features of many cancers, especially lymphoma and leukemia. However, recent reports suggest that many chromosomal translocations can be found in healthy individuals, although the significance of this observation is still not clear. In this review, we summarize recent studies on chromosomal translocations in healthy individuals carried out in different geographical areas of the world and discuss the relevance of the observation with respect to oncogenesis.
authors.affiliation: Department of Biochemistry, Indian Institute of Science, Bangalore, 560 012, India.
authors.forename: Mridula
authors.initials: M
authors.lastname: Nambiar
authors.forename: Sathees C
authors.initials: SC
authors.lastname: Raghavan
mesh_terms: D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D005828:Genetics, Population; D006801:Humans; D009369:Neoplasms / Q000235:genetics*; D014178:Translocation, Genetic