title: [Fetal heart rate variability and clozapine treatment].
abstract: We report the 2 cases of schizophrenic patients with clozapine treatment and particularly, we underlined a reduced variability and low short-term variability, whereas biophysical ultrasound score, Dopplers and perception of fetal movements were acceptable and comfortable concerning the fetal vitality. Our aim is to show the limits of the analyzed fetal heart rate under clozapine. So, we may change our observation of fetus in chronic suffering that is usually mainly made with an informatics analysis of pregnants under clozapine.
authors.affiliation: Service de gynécologie-obstétrique et médecine de la reproduction, hôpital Couple Enfant, université Joseph-Fourrier Grenoble 1, CHU de Grenoble, BP 217, 38043 Grenoble cedex 9, France. anne_laurecoston@yahoo.fr
authors.forename: A-L
authors.initials: AL
authors.lastname: Coston
authors.forename: P
authors.initials: P
authors.lastname: Hoffmann
authors.forename: V
authors.initials: V
authors.lastname: Equy
authors.forename: F
authors.initials: F
authors.lastname: Sergent
authors.forename: C
authors.initials: C
authors.lastname: Vidal
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D003024:Clozapine / Q000009:adverse effects*; D005260:Female; D005324:Fetal Movement / Q000187:drug effects; D005865:Gestational Age; D006340:Heart Rate, Fetal / Q000187:drug effects*; D006801:Humans; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications / Q000523:psychology*; D012559:Schizophrenia / Q000150:complications* / Q000188:drug therapy; D016216:Ultrasonography, Prenatal
chemical_list: D014150:Antipsychotic Agents; D003024:Clozapine