title: Jaccoud arthropathy in systemic lupus erythematosus: clinical and serological findings.
abstract: OBJECTIVE
  To study the prevalence of Jaccoud arthropathy (JA) in a sample of local systemic lupus erythematosus (SLE) patients and its clinical and serological associations.
  
  
  METHODS
  308 SLE patients from a single university center for the last two years were interviewed and examined. The presence of JA was searched for according to the JA index. After this, charts were reviewed for clinical and serological profile.
  
  
  RESULTS
  The studied sample was composed by 94.5% females and 5.5% males with mean age of 38.08 ± 12.04 years and mean disease duration of 29.68 ± 11.63 years. A JA prevalence of 6.1% was found in this sample. There was a positive association of JA presence with arthritis complaints (p = 0.001) and a negative association with renal involvement (p = 0.028). Patients with JA had higher positivity for anti-dsDNA (p = 0.022).
  
  
  CONCLUSIONS
  Despite the positive association of JA with arthritis and anti-dsDNA, there was a negative association with nephritis. This could suggest that JA patients belong with a SLE subset with a better prognosis.
authors.affiliation: Instituto de Pesquisa Médica, Faculdade Evangélica do Paraná, Curitiba, PR, Brazil. tskare@onda.com.br
authors.forename: Thelma L
authors.initials: TL
authors.lastname: Skare
authors.forename: Andressa de Lima
authors.initials: Ade L
authors.lastname: Godoi
authors.forename: Valéria O
authors.initials: VO
authors.lastname: Ferreira
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000974:Antibodies, Antinuclear / Q000097:blood; D001168:Arthritis / Q000097:blood / Q000150:complications; D001323:Autoantibodies / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007592:Joint Diseases / Q000097:blood / Q000150:complications / Q000453:epidemiology*; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000150:complications*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012698:Serologic Tests / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D000974:Antibodies, Antinuclear; D001323:Autoantibodies; D015415:Biomarkers