title: [Preliminary report of laryngeal preservation in the surgical salvage of recurrent laryngeal cancer].
abstract: OBJECTIVE
  To explore the plausibility of laryngeal preservation in salvage surgery of recurrent laryngeal carcinoma.
  
  
  METHODS
  Comprehensive clinical and radiological assessments on a specific group of patients with recurrent laryngeal cancer and their relapsed tumors were carried out to determine the methods and indications of salvage surgery for preservation of laryngeal functions. Salvage surgery with preservation of larynx was performed in a selective of 36 laryngeal cancer patients with relapsed tumors in their larynges after radiotherapy or partial laryngectomies. All patients were regularly followed up after discharge from the hospital. Postoperative survival was calculated by Kaplan-Meier's method.
  
  
  RESULTS
  Among various laryngeal preservation regimens given, a second transoral laser surgery was carried out in 4 cases, horizontal hemilaryngectomy in 4 cases, vertical hemilaryngectomy in 13 cases and Majer-Piquet's operation in 15 cases, respectively. Simultaneous neck dissection was conducted in 18 cases. Postoperative complications were encountered in 6 cases, most common of which were local infection and laryngeal fistula with no hospital mortality and other major morbidities. Five cases with immediate postoperative complications were cured with proper management. The remained one case undergone vertical partial laryngectomy for recurrence after tumor resection via laryngeal fissure received postoperative radiation due to positive surgical margin, and complicated laryngeal atresia and obstruction with loss of his laryngeal functions. Local recurrence was observed in 5 cases and simultaneous locoregional recurrence was seen in 1 case, with the resulting local control rate of 83.3% (30/36). The 3-year postoperative survival rate was 80.6%. The cause of death was tumor recurrence in 3 cases, distant metastasis in 3 cases and non-tumor-associated disease (heart attack) in 1 case, respectively.
  
  
  CONCLUSIONS
  Salvage surgery with laryngeal preservation can be carried out in the selected cases with early or locally-confined recurrent lesions within the larynx, on the condition that the recurrent tumors be assessed thoroughly and indications for associated surgical techniques be evaluated properly.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Bethune International Peace Hospital, Shijiazhuang 050082, China. xml_968@sohu.com
authors.forename: Xiao-ming
authors.initials: XM
authors.lastname: Li
authors.forename: Bin
authors.initials: B
authors.lastname: DI
authors.forename: Zhen-feng
authors.initials: ZF
authors.lastname: Tao
authors.forename: Qi
authors.initials: Q
authors.lastname: Song
authors.forename: Shu-fen
authors.initials: SF
authors.lastname: Xiao
authors.forename: Hong-xia
authors.initials: HX
authors.lastname: Li
authors.forename: Yong-liang
authors.initials: YL
authors.lastname: Shao
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D016879:Salvage Therapy; D016896:Treatment Outcome