title: Skin tightening induced by fractional CO(2) laser treatment: quantified assessment of variations in mechanical properties of the skin.
abstract: BACKGROUND
  Certain authors have reported the efficacy of fractional resurfacing laser treatment in patients with photodamaged skin resulting in skin tightening of treated area.
  
  
  OBJECTIVE
  To assess skin tightening after CO(2) fractional resurfacing laser treatment by measuring variations in mechanical properties in treated areas. Dermal elasticity was measured using suction applied with an in vivo skin elasticity meter (Cutometer(®)).
  
  
  METHODS
  A prospective observational study was undertaken from January 2007 to August 2009. Laser treatment was performed with the SmartXide Dot(®) (Deka(®), Firenze, Italy) CO(2) fractional resurfacing device. Patients were offered quantified analysis using the Cutometer(®) before and after treatment.
  
  
  RESULTS
  Seventeen patients (61 areas treated) were included in the study. Median delay between before and after cutometric evaluations was 80 days. We found significant improvement in elastic (R2 +5.9%), viscoelastic (R8 -9.4%), fatigue (R3 and R9 -16.2% and -19.7%, respectively), and thickness (R0 -14.9%) parameters. These results are consistent with significant tightening and also elastic tissue improvement.
  
  
  CONCLUSIONS
  It was possible to quantify skin tightening because of CO(2) fractional laser treatment using a noninvasive technique.
authors.affiliation: Université Francois Rabelais de Tours, France. michaelnaouri@yahoo.fr
authors.forename: Michael
authors.initials: M
authors.lastname: Naouri
authors.forename: Michael
authors.initials: M
authors.lastname: Atlan
authors.forename: Elodie
authors.initials: E
authors.lastname: Perrodeau
authors.forename: Gabriela
authors.initials: G
authors.lastname: Georgesco
authors.forename: Randa
authors.initials: R
authors.lastname: Khallouf
authors.forename: Ludovic
authors.initials: L
authors.lastname: Martin
authors.forename: Laurent
authors.initials: L
authors.lastname: Machet
mesh_terms: D000328:Adult; D004548:Elasticity; D006801:Humans; D057194:Intention to Treat Analysis; D054020:Lasers, Gas / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D011446:Prospective Studies; D012060:Rejuvenation; D015595:Skin Aging; D012879:Skin Physiological Phenomena