title: Surgical outcomes of hepatocellular carcinoma originating from caudate lobe.
abstract: BACKGROUND
  Caudate resection for hepatocellular carcinoma (HCC) remains a challenging procedure. This study aimed to assess the surgical outcomes of HCC originating from caudate lobe.
  
  
  METHODS
  Twenty-three patients with HCC in the caudate lobe who received surgical treatment were retrospectively reviewed.
  
  
  RESULTS
  Surgical procedures included 13 isolated caudatectomy (56.5%) and 10 combined caudatectomy (43.5%). Eight patients (34.7%) experienced post-operative complications. Mortality was nil. The 1-, 3- and 5-year overall survival rates after surgery were 90.1%, 60% and 37%, respectively. Isolated caudatectomy was associated with less frequent tumours located in paracaval portion, longer operative time, longer vascular occlusion time and more blood loss than combined caudatectomy (P < 0.05).
  
  
  CONCLUSIONS
  Surgical resection is feasible and beneficial for patients with HCC in the caudate lobe. If liver functional reserve is sufficient, combined caudatectomy is preferred.
authors.affiliation: Department of Hepato-Biliary-Pancreato-Vascular Surgery, First Affiliated Hospital of Xiamen University, Xiamen, China.
authors.forename: Yanming
authors.initials: Y
authors.lastname: Zhou
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Zhang
authors.forename: Lupeng
authors.initials: L
authors.lastname: Wu
authors.forename: Donghui
authors.initials: D
authors.lastname: Xu
authors.forename: Bin
authors.initials: B
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000601:surgery*; D016009:Chi-Square Distribution; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome