title: Transcriptional regulation of plant secondary metabolism.
abstract: Plant secondary metabolites play critical roles in plant-environment interactions. They are synthesized in different organs or tissues at particular developmental stages, and in response to various environmental stimuli, both biotic and abiotic. Accordingly, corresponding genes are regulated at the transcriptional level by multiple transcription factors. Several families of transcription factors have been identified to participate in controlling the biosynthesis and accumulation of secondary metabolites. These regulators integrate internal (often developmental) and external signals, bind to corresponding cis-elements--which are often in the promoter regions--to activate or repress the expression of enzyme-coding genes, and some of them interact with other transcription factors to form a complex. In this review, we summarize recent research in these areas, with an emphasis on newly-identified transcription factors and their functions in metabolism regulation.
authors.affiliation: National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, the Chinese Academy of Sciences, Shanghai 200032, China.
authors.forename: Chang-Qing
authors.initials: CQ
authors.lastname: Yang
authors.forename: Xin
authors.initials: X
authors.lastname: Fang
authors.forename: Xiu-Ming
authors.initials: XM
authors.lastname: Wu
authors.forename: Ying-Bo
authors.initials: YB
authors.lastname: Mao
authors.forename: Ling-Jian
authors.initials: LJ
authors.lastname: Wang
authors.forename: Xiao-Ya
authors.initials: XY
authors.lastname: Chen
mesh_terms: D000470:Alkaloids / Q000378:metabolism; D018506:Gene Expression Regulation, Plant / Q000235:genetics / Q000502:physiology; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D013729:Terpenes / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D000470:Alkaloids; D010940:Plant Proteins; D013729:Terpenes; D014157:Transcription Factors