title: Local staging of prostate cancer: comparative accuracy of T2-weighted endorectal MR imaging and transrectal ultrasound.
abstract: OBJECTIVE
  The objective of this study was to compare the accuracy of T2-weighted magnetic resonance (MR) imaging and transrectal ultrasound (TRUS) for staging of prostate cancer.
  
  
  METHODS
  A total of 101 men with biopsy-proven prostate cancer undergoing both T2-weighted endorectal MR imaging and B-mode TRUS for local tumor staging prior to radical prostatectomy were retrospectively identified. Three MR readers rated the likelihood of locally advanced disease using a 5-point scale. An ultrasound reader performed the same rating. Staging accuracy was compared using receiver operating characteristic curves.
  
  
  RESULTS
  Staging accuracy was not significantly different between MR imaging (A(z) = 0.69-0.70) and TRUS (A(z) = 0.81, P>.05).
  
  
  CONCLUSIONS
  T2-weighted MR imaging demonstrates comparable accuracy to B-mode TRUS for depicting locally invasive prostate cancer.
authors.affiliation: Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Ave, San Francisco, CA 94143-0628, USA. adam.jung@ucsf.edu
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Jung
authors.forename: Fergus V
authors.initials: FV
authors.lastname: Coakley
authors.forename: Katsuto
authors.initials: K
authors.lastname: Shinohara
authors.forename: Peter R
authors.initials: PR
authors.lastname: Carroll
authors.forename: John
authors.initials: J
authors.lastname: Kurhanewicz
authors.forename: Janet E
authors.initials: JE
authors.lastname: Cowan
authors.forename: Antonio C
authors.initials: AC
authors.lastname: Westphalen
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D012372:ROC Curve; D012189:Retrospective Studies; D014463:Ultrasonography; D036761:Ultrasound, High-Intensity Focused, Transrectal / Q000379:methods*