title: [Medical mistakes due to generic substitution].
abstract: Generic substitution is a major cause of medical mistakes in the general population. Danish legislation obligates pharmacies to substitute prescribed medicine with the cheapest equivalent formulation, despite variations in product name, packaging, shape and colour. Consequently, medical mistakes occur. Scientific evidence on the consequences of generic substitution is sparse. Call upon fellow health workers to report medical mistakes to the national entities and scientific peers, in order to increase awareness and scientific evidence about the problem.
authors.affiliation: Ortopædisk Forskningslaboratorium, Aarhus Universitetshospital, Nørrebrogade 44, bygning 1A, 8000 Aarhus C, Denmark. jan.roelfing@ki.au.dk
authors.forename: Jan Hendrik Duedal
authors.initials: JH
authors.lastname: Rölfing
mesh_terms: D017311:Amlodipine / Q000009:adverse effects / Q000191:economics; D000959:Antihypertensive Agents / Q000009:adverse effects / Q000191:economics; D016527:Drug Costs; D004348:Drug Labeling / Q000592:standards; D011307:Drug Prescriptions / Q000592:standards; D057915:Drug Substitution / Q000009:adverse effects*; D016568:Drugs, Generic / Q000009:adverse effects*; D005260:Female; D006801:Humans; D017706:Lisinopril / Q000009:adverse effects / Q000191:economics; D008508:Medication Errors; D008875:Middle Aged; D061214:Patient Safety
chemical_list: D000959:Antihypertensive Agents; D016568:Drugs, Generic; D017311:Amlodipine; D017706:Lisinopril