title: Bilateral, multicenteric metanephric adenoma associated with Wilms' tumor in a child: a rare presentation with important diagnostic and therapeutic implications.
abstract: Metanephric adenoma is an uncommon benign renal tumor that occurs predominantly in adult females and rarely in children. On histomorphology it shows a resemblance to Wilms' tumor, nephrogenic rests and papillary renal cell carcinoma. Multifocality along with multicentricity has not been documented in English literature till date. From a diagnostic and therapeutic viewpoint, recognition of this entity is of the utmost importance, because it shows a favorable clinical outcome. We describe a rare case of bilateral, multicentric metanephric adenoma associated with triphasic Wilms' tumor (stage II) of the left kidney in a male child.
authors.affiliation: Department of Pathology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India.
authors.forename: Sunil
authors.initials: S
authors.lastname: Pasricha
authors.forename: Jatin S
authors.initials: JS
authors.lastname: Gandhi
authors.forename: Gurudutt
authors.initials: G
authors.lastname: Gupta
authors.forename: Anurag
authors.initials: A
authors.lastname: Mehta
authors.forename: Shaham
authors.initials: S
authors.lastname: Beg
mesh_terms: D000236:Adenoma / Q000188:drug therapy / Q000473:pathology*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D002675:Child, Preschool; D003609:Dactinomycin / Q000008:administration & dosage; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000628:therapy; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000628:therapy; D009392:Nephrectomy; D014750:Vincristine / Q000008:administration & dosage; D009396:Wilms Tumor / Q000473:pathology* / Q000628:therapy
chemical_list: D003609:Dactinomycin; D014750:Vincristine