title: How to diagnose and phenotype asthma.
abstract: Asthma has been described as a chronic disease of the airways characterized by variable airflow obstruction, airway hyperresponsiveness, and airway inflammation. This review discusses the diagnosis and phenotyping of asthma, with a special emphasis on phenotyping based on the nature of cellular inflammation and radiological imaging and how this could be used to direct the treatment of asthma and, in the future, to apply specifically directed therapies to specific phenotypes.
authors.affiliation: Department of Medicine, St Joseph's Healthcare, McMaster University, 50 Charlton Avenue East, Hamilton, Ontario L8N4A6, Canada. parames@mcmaster.ca
authors.forename: Parameswaran
authors.initials: P
authors.lastname: Nair
authors.forename: Angira
authors.initials: A
authors.lastname: Dasgupta
authors.forename: Christopher E
authors.initials: CE
authors.lastname: Brightling
authors.forename: Kian Fan
authors.initials: KF
authors.lastname: Chung
mesh_terms: D001249:Asthma / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D007249:Inflammation; D010641:Phenotype