title: Heart rate variability in peritoneal dialysis patients: what is the role of residual renal function?.
abstract: BACKGROUND
  The relationship between heart rate variability (HRV) and residual renal function (RRF) has not been elucidated previously.
  
  
  METHODS
  In this cross-sectional study, HRV was evaluated in 71 peritoneal dialysis patients. Patients were divided into RRF decline group, RRF stable group and anuric group.
  
  
  RESULTS
  RRF was negatively correlated with SDNN (r = -0.284, p = 0.017), TP (r = -0.247, p = 0.039), and HF (r = -0.238, p = 0.047). Significant sympathetic nerve activation was found in the RRF decline group (significantly lower SDNN, SDSD, RMSSD, pNN50, LF, HF, TP and higher LF/HF ratio) as compared to the RRF stable and anuric groups. Besides, significantly parasympathetic activation was found in the anuric group (the lowest LF/HF ratio as compared to the other groups (both p < 0.05). Multivariate stepwise regression analysis showed that the status of RRF was an independent factor associated with HRV parameters.
  
  
  CONCLUSIONS
  This study showed autonomic nervous function in peritoneal dialysis patients was associated with a different status of RRF.
authors.affiliation: Division of Nephrology, Peking University Third Hospital, Beijing, PR China.
authors.forename: Wen
authors.initials: W
authors.lastname: Tang
authors.forename: Li-Xian
authors.initials: LX
authors.lastname: Li
authors.forename: Juan
authors.initials: J
authors.lastname: Pei
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
mesh_terms: D000368:Aged; D005260:Female; D005919:Glomerular Filtration Rate; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis; D013564:Sympathetic Nervous System