title: Sarcopenia: pharmacology of today and tomorrow.
abstract: Sarcopenia remains largely undiagnosed and undertreated because of the lack of a universally accepted definition, effective ways to measure it, and identification of the outcomes that should guide treatment efficacy. An ever-growing number of clinicians and researchers along with funding and regulatory agencies have gradually recognized that sarcopenia is a human condition that requires both prevention and treatment. In this article, we review sarcopenia and its common and less known pharmacological treatments, attempt to define sarcopenia in its broader context, and present some new ideas for potential future treatment for this devastating condition.
authors.affiliation: Muscle Biology Research Group-MUBIG, University of Missouri-Kansas City, School of Nursing, Kansas City, MO 64108, USA. brottom@umkc.edu
authors.forename: Marco
authors.initials: M
authors.lastname: Brotto
authors.forename: Eduardo L
authors.initials: EL
authors.lastname: Abreu
mesh_terms: D000375:Aging / Q000378:metabolism; D000818:Animals; D004032:Diet; D006801:Humans; D053580:Muscle Strength / Q000502:physiology; D018482:Muscle, Skeletal / Q000187:drug effects / Q000254:growth & development / Q000503:physiopathology*; D055070:Resistance Training; D055948:Sarcopenia / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology