title: DKK1 as a novel target for myeloma immunotherapy.
abstract: Novel, potent tumor-associated antigens are needed to improve the efficacy of immunotherapy for myeloma. We demonstrated that active vaccination using the DKK1-DNA vaccine in the myeloma mouse model protected mice from developing myeloma and effectively treated established myeloma. Therefore, DKK1 could be developed as a novel vaccine for myeloma immunotherapy.
authors.affiliation: Department of Lymphoma/Myeloma; Division of Cancer Medicine; Center for Cancer Immunology Research; The University of Texas MD Anderson Cancer Center; Houston, TX USA.
authors.forename: Jianfei
authors.initials: J
authors.lastname: Qian
authors.forename: Qing
authors.initials: Q
authors.lastname: Yi