title: Small signaling peptides in Arabidopsis development: how cells communicate over a short distance.
abstract: To sustain plants' postembryonic growth and development in a structure of cells fixed in cell walls, a tightly controlled short distance cell-cell communication is required. The focus on phytohormones, such as auxin, has historically overshadowed the importance of small peptide signals, but it is becoming clear that secreted peptide signals are important in cell-cell communication to coordinate and integrate cellular functions. However, of the more than 1000 potential secreted peptides, so far only very few have been functionally characterized or matched to a receptor. Here, we will describe our current knowledge on how small peptide signals can be identified, how they are modified and processed, which roles they play in Arabidopsis thaliana development, and through which receptors they act.
authors.affiliation: Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough, Leicestershire LE12 5RD, United Kingdom.
authors.forename: Evan
authors.initials: E
authors.lastname: Murphy
authors.forename: Stephanie
authors.initials: S
authors.lastname: Smith
authors.forename: Ive
authors.initials: I
authors.lastname: De Smet
mesh_terms: D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000254:growth & development* / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000378:metabolism; D002450:Cell Communication; D002454:Cell Differentiation; D008565:Membrane Proteins / Q000378:metabolism; D059828:Plant Cells / Q000502:physiology*; D054046:Plant Stomata / Q000254:growth & development / Q000378:metabolism; D058526:Plant Vascular Bundle / Q000378:metabolism; D011499:Protein Processing, Post-Translational; D021382:Protein Sorting Signals; D059748:Proteolysis; D055571:Secretory Pathway; D012639:Seeds / Q000254:growth & development / Q000378:metabolism
chemical_list: D029681:Arabidopsis Proteins; C506683:CLE40 protein, Arabidopsis; C401621:CLV2 protein, Arabidopsis; D008565:Membrane Proteins; D021382:Protein Sorting Signals