title: A novel copper-catalyzed reductive coupling of N-tosylhydrazones with H-phosphorus oxides.
abstract: We report here a novel C(sp(3))-P bonds formation via copper-catalyzed reductive coupling of N-tosylhydrazones with H-phosphorus oxides. A variety of aliphatic and aromatic substrates bearing electron-rich and electron-deficient substituents affords phosphine oxide derivatives with moderate to good yields. This work suggests a new transformation of aldehydes/ketones via N-tosylhydrazones to organophosphorus compounds.
authors.affiliation: Department of Chemistry, College of Sciences, Nanjing Agricultural University, Nanjing 210095, Peoples' Republic of China. rickywu@iccas.ac.cn
authors.forename: Lei
authors.initials: L
authors.lastname: Wu
authors.forename: Xio
authors.initials: X
authors.lastname: Zhang
authors.forename: Qing-Qing
authors.initials: QQ
authors.lastname: Chen
authors.forename: An-Kun
authors.initials: AK
authors.lastname: Zhou
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006835:Hydrazones / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D009943:Organophosphorus Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry*
chemical_list: D006835:Hydrazones; D009942:Organometallic Compounds; D009943:Organophosphorus Compounds; D010087:Oxides; D003300:Copper