title: Management of myelofibrosis: a survey of current practice in the United Kingdom.
abstract: OBJECTIVE
  To investigate the experience of clinicians in the management of patients with myelofibrosis, current treatment options and their utility.
  
  
  METHODS
  We used an internet-based survey
  
  
  RESULTS
  Of 105 respondents (mostly consultants), 79% identified bothersome symptoms as the most common issue to be addressed, while for 19%, lack of efficacy of treatment fell into this category. The survey found that a wide variety of treatments are employed but with poor perceived efficacy.
  
  
  CONCLUSIONS
  This is the first UK based assessment of management of myelofibrosis. Perspectives may evolve with the inception of novel therapeutics in this field , but clinical guidelines for effective management currently recommend a wide variety of agents and suggest a limited likely success rate.
authors.affiliation: Department of Haematology, Guys and St Thomas' NHS Foundation Trust, Guy's Hospital, London, UK.
authors.forename: Moosa Rashid
authors.initials: MR
authors.lastname: Qureshi
authors.forename: Cathy
authors.initials: C
authors.lastname: MacLean
authors.forename: Mary Frances
authors.initials: MF
authors.lastname: McMullin
authors.forename: Claire
authors.initials: C
authors.lastname: Harrison
mesh_terms: D019538:Health Care Surveys; D006801:Humans; D020407:Internet; D010818:Practice Patterns, Physicians'; D055728:Primary Myelofibrosis / Q000628:therapy*; D006113:United Kingdom