title: Post-surgical hemorrhagic infarction of the adrenal gland as the first clinical manifestation of antiphospholipid syndrome after 43 years of antibody-positivity.
abstract: We report on a male patient who tested positive for antiphospholipid antibodies for 43 years without thromboembolic manifestation of antiphospholipid syndrome (APS). He has been followed up in a prospective cohort study since 2001. Following his second hip replacement surgery, the patient developed acute adrenal failure due to bilateral hemorrhagic infarction. Prophylactic anticoagulation, surgery, or an immunological reaction to blood transfusion may have triggered this late and unusually located primary manifestation of APS in our patient.
authors.affiliation: Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
authors.forename: Johanna
authors.initials: J
authors.lastname: Haselboeck
authors.forename: Helmut
authors.initials: H
authors.lastname: Ringl
authors.forename: Catharina
authors.initials: C
authors.lastname: Mueller
authors.forename: Ingrid
authors.initials: I
authors.lastname: Pabinger
authors.forename: Stefan
authors.initials: S
authors.lastname: Winkler
mesh_terms: D000311:Adrenal Glands / Q000098:blood supply*; D000368:Aged; D017152:Antibodies, Antiphospholipid; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000276:immunology; D006801:Humans; D007238:Infarction / Q000209:etiology* / Q000276:immunology; D008297:Male
chemical_list: D017152:Antibodies, Antiphospholipid