title: [Role of opportunistic infection causative agent in etiology of obstructive bronchitis and prolonged subfebrility in children].
abstract: OBJECTIVE
  Determine the role of opportunistic infections causative agents in ethology of obstructive bronchitises and prolonged subfebrilities in children.
  
  
  METHODS
  56 children with the diagnosis of obstructive bronchitis and 46 children with the diagnosis of prolonged subfebrility were examined for the presence of herpes, mycoplasma and pneumocystic infections. EIA, IIF, rapid culture method, PCR were used.
  
  
  RESULTS
  The highest number of cases of mixed infection was detected in children with HHV-6 infection. Mixed infection was diagnosed 6 times more frequently in children with obstructive bronchitis and 9 times in children with prolonged subfebrility. The number of children with pneumocystosis in combination with other infections was 2.4 and 2 times higher than with monoinfection; with CMV infection--4 and 2 times; with HSV infection--5 and 4 times; EBV infection--6 and 3.7 times. The only exception was mycoplasmosis detected in children with obstructive bronchitis where the difference between the number of mono and mixed infection cases was insignificant.
  
  
  CONCLUSIONS
  The data obtained give evidence of wide spread of opportunistic infections.
authors.forename: T N
authors.initials: TN
authors.lastname: Rybalkina
authors.forename: N V
authors.initials: NV
authors.lastname: Karazhas
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Kalugina
authors.forename: R E
authors.initials: RE
authors.lastname: Bosh'ian
authors.forename: M N
authors.initials: MN
authors.lastname: Kornienko
authors.forename: R R
authors.initials: RR
authors.lastname: Adgamov
authors.forename: L V
authors.initials: LV
authors.lastname: Feklisova
authors.forename: M K
authors.initials: MK
authors.lastname: Khadisova
authors.forename: T M
authors.initials: TM
authors.lastname: Lebedeva
mesh_terms: D015415:Biomarkers / Q000097:blood; D001991:Bronchitis / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D002648:Child; D002908:Chronic Disease; D060085:Coinfection / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D003586:Cytomegalovirus Infections / Q000097:blood / Q000150:complications / Q000175:diagnosis; D004797:Enzyme-Linked Immunosorbent Assay; D020031:Epstein-Barr Virus Infections / Q000097:blood / Q000150:complications / Q000175:diagnosis; D005334:Fever / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D006561:Herpes Simplex / Q000097:blood / Q000150:complications / Q000175:diagnosis; D015654:Herpesvirus 6, Human / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D009175:Mycoplasma Infections / Q000097:blood / Q000150:complications / Q000175:diagnosis; D009894:Opportunistic Infections / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D011020:Pneumonia, Pneumocystis / Q000097:blood / Q000150:complications / Q000175:diagnosis; D016133:Polymerase Chain Reaction; D019349:Roseolovirus Infections / Q000097:blood / Q000150:complications / Q000175:diagnosis
chemical_list: D015415:Biomarkers; D007136:Immunoglobulins