title: Impairment of green-lipped mussel (Perna canaliculus) physiology by waterborne cadmium: relationship to tissue bioaccumulation and effect of exposure duration.
abstract: Laboratory studies were performed to assess the impact of acute and subchronic cadmium (Cd) exposure on the green-lipped mussel, Perna canaliculus. A 96 h median lethal concentration (LC(50)) value of 8160 μg L(-1) was determined, characterising this species as relatively tolerant to Cd exposure. Acute (96 h; at 2000 and 4000 μg Cd L(-1)) and subchronic (28 d; at 200 and 2000 μg Cd L(-1)) waterborne exposures were then conducted to investigate the impact of Cd exposure on physiological responses (e.g. clearance (feeding) rate, absorption efficiency, oxygen uptake, ammonia production, oxygen to nitrogen ratio, scope for growth) and tissue Cd accumulation. Cd accumulation in digestive gland showed saturation with respect to increasing exposure concentration, while the gill tissue Cd accumulation followed a positive linear relationship with Cd exposure level. Clearance rates declined during both acute and subchronic exposures at levels of 2000 μg Cd L(-1) or higher. Impairments of clearance rates were strongly correlated with tissue Cd accumulation. Coupled with their importance as a food source, and their wide coastal distribution, these data suggests that P. canaliculus may be a species useful as an indicator species for trace metal pollution in coastal environments.
authors.affiliation: School of Biological Sciences, University of Canterbury, Christchurch 8140, New Zealand. rch118@uclive.ac.nz
authors.forename: Rathishri
authors.initials: R
authors.lastname: Chandurvelan
authors.forename: Islay D
authors.initials: ID
authors.lastname: Marsden
authors.forename: Sally
authors.initials: S
authors.lastname: Gaw
authors.forename: Chris N
authors.initials: CN
authors.lastname: Glover
mesh_terms: D000641:Ammonia / Q000378:metabolism; D000818:Animals; D002104:Cadmium / Q000493:pharmacokinetics* / Q000633:toxicity*; D019069:Cell Respiration / Q000187:drug effects; D004781:Environmental Exposure; D008657:Metabolic Clearance Rate / Q000187:drug effects; D049883:Perna / Q000187:drug effects* / Q000502:physiology; D013997:Time Factors; D014874:Water Pollutants, Chemical / Q000493:pharmacokinetics* / Q000633:toxicity*
chemical_list: D014874:Water Pollutants, Chemical; D002104:Cadmium; D000641:Ammonia