title: Insights from the genome sequence of a Salmonella enterica serovar Typhi strain associated with a sporadic case of typhoid fever in Malaysia.
abstract: Salmonella enterica serovar Typhi is the causative agent of typhoid fever, which causes nearly 21.7 million illnesses and 217,000 deaths globally. Herein, we describe the whole-genome sequence of the Salmonella Typhi strain ST0208, isolated from a sporadic case of typhoid fever in Kuala Lumpur, Malaysia. The whole-genome sequence and comparative genomics allow an in-depth understanding of the genetic diversity, and its link to pathogenicity and evolutionary dynamics, of this highly clonal pathogen that is endemic to Malaysia.
authors.affiliation: Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: Kien-Pong
authors.initials: KP
authors.lastname: Yap
authors.forename: Cindy Shuan Ju
authors.initials: CS
authors.lastname: Teh
authors.forename: Ramani
authors.initials: R
authors.lastname: Baddam
authors.forename: Lay-Ching
authors.initials: LC
authors.lastname: Chai
authors.forename: Narender
authors.initials: N
authors.lastname: Kumar
authors.forename: Tiruvayipati Suma
authors.initials: TS
authors.lastname: Avasthi
authors.forename: Niyaz
authors.initials: N
authors.lastname: Ahmed
authors.forename: Kwai-Lin
authors.initials: KL
authors.lastname: Thong
mesh_terms: D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics*; D016680:Genome, Bacterial; D008296:Malaysia; D008969:Molecular Sequence Data; D012485:Salmonella typhi / Q000235:genetics* / Q000302:isolation & purification; D017422:Sequence Analysis, DNA; D014435:Typhoid Fever / Q000382:microbiology
chemical_list: D004269:DNA, Bacterial