title: [Effects of acupoint injection of autologous blood on symptoms and plasma motilin and gastrin levels of diabetic gastroparesis patients].
abstract: OBJECTIVE
  To observe the curative effect of autologous blood point injection on diabetic gastroparesis and to study its underlying mechanism.
  
  
  METHODS
  A total of 42 type-II diabetes outpatients and inpatients were randomly and equally divided into treatment group and control group according to a random digit table. Patients of the treatment group were treated by injection of the patient's own venous blood (2 mL/acupoint) into the unilateral Zusanli (ST 36), Zhongwan (OV 12) and Weishu (BL 21), once every week, 4 times together. Patients of the control group were ordered to take motilium (10 mg/time), 3 times daily for 4 weeks. Plasma motilin and gastrin were detected by radioimmunoassay before and 4 weeks after the treatment.
  
  
  RESULTS
  Of the two 21 cases in the control and treatment groups, 3 and 7 experienced marked improvement in their symptoms, 4 and 8 were effective, 14 and 6 were failed in the treatment, with the effective rates being 33.3% and 71.4% respectively. The effective rate of the treatment group was significantly higher than that of the control group (P<0.05). The contents of plasma motilin and gastrin in both control and treatment groups were reduced obviously after the treatment (P<0.01), and the effect of the treatment group was significantly superior to that of the control group in lowering plasma motilin and gastrin levels (P<0.01).
  
  
  CONCLUSIONS
  Acupoint injection of the diabetes patients' own blood can obviously alleviate the symptoms of diabetic gastroparesis, which is closely associated with its effects in lowering plasma motilin and gastrin levels.
authors.affiliation: Department of Chinese Medicine, Xiangyang Municipal Central Hospital of Hubei Province, Xiangyang 441021, China. chenlimail@163.com
authors.forename: Li
authors.initials: L
authors.lastname: Chen
authors.forename: Xin-Feng
authors.initials: XF
authors.lastname: Zhang
authors.forename: Bao-Qing
authors.initials: BQ
authors.lastname: Ku
authors.forename: Xiao-Cui
authors.initials: XC
authors.lastname: Wang
authors.forename: Cong
authors.initials: C
authors.lastname: Ma
authors.forename: Jun-Yan
authors.initials: JY
authors.lastname: Liang
authors.forename: Juan
authors.initials: J
authors.lastname: Liu
mesh_terms: D015669:Acupuncture Points; D000293:Adolescent; D000328:Adult; D000368:Aged; D001804:Blood Transfusion, Autologous; D048909:Diabetes Complications / Q000097:blood / Q000628:therapy*; D005260:Female; D005755:Gastrins / Q000097:blood*; D018589:Gastroparesis / Q000097:blood / Q000628:therapy*; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D009037:Motilin / Q000097:blood*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D005755:Gastrins; D009037:Motilin