title: Does human evolution in different latitudes influence susceptibility to obesity via the circadian pacemaker?: migration and survival of the fittest in the modern age of lifestyle-induced circadian desynchrony.
abstract: The variable photoperiods of Northern latitudes challenge the entrainment capacity of the circadian pacemaker, which evolved under constant photoperiods in Equatorial regions. Entrainment to the erratic photoperiods facilitated by artificial light presents an additional challenge. Metabolic dysfunction and obesity are potential consequences of such desynchronization of circadian and environmental rhythms.
authors.affiliation: Institute of Biological and Environmental Science, University of Aberdeen, Aberdeen, UK. c.wyse@abdn.ac.uk
authors.forename: Cathy A
authors.initials: CA
authors.lastname: Wyse
mesh_terms: D001683:Biological Clocks / Q000502:physiology*; D005075:Biological Evolution; D002940:Circadian Rhythm / Q000502:physiology*; D004198:Disease Susceptibility / Q000473:pathology* / Q000503:physiopathology; D005843:Geography; D006706:Homeostasis; D063426:Human Migration; D006801:Humans; D008019:Life Style; D009765:Obesity / Q000503:physiopathology*; D013534:Survival