title: Future trials of endovascular mechanical recanalisation therapy in acute ischemic stroke patients - a position paper endorsed by ESMINT and ESNR : part II: methodology of future trials.
abstract: Based on current data and experience, the joint working group of the European Society of Minimally Invasive Neurological Therapy (ESMINT) and the European Society of Neuroradiology (ESNR) make suggestions on trial design and conduct aimed to investigate therapeutic effects of mechanical thrombectomy (MT). We anticipate that this roadmap will facilitate the setting up and conduct of successful trials in close collaboration with our neighbouring disciplines.
authors.affiliation: Department of Neuroradiology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany. fiehler@uke.uni-hamburg.de
authors.forename: Jens
authors.initials: J
authors.lastname: Fiehler
authors.forename: Michael
authors.initials: M
authors.lastname: Söderman
authors.forename: Francis
authors.initials: F
authors.lastname: Turjman
authors.forename: Philip M
authors.initials: PM
authors.lastname: White
authors.forename: Søren Jacob
authors.initials: SJ
authors.lastname: Bakke
authors.forename: Salvatore
authors.initials: S
authors.lastname: Mangiafico
authors.forename: Rüdiger
authors.initials: R
authors.lastname: von Kummer
authors.forename: Mario
authors.initials: M
authors.lastname: Muto
authors.forename: Christophe
authors.initials: C
authors.lastname: Cognard
authors.forename: Jan
authors.initials: J
authors.lastname: Gralla
mesh_terms: D002545:Brain Ischemia / Q000175:diagnosis* / Q000628:therapy*; D002986:Clinical Trials as Topic / Q000592:standards*; D023381:Endpoint Determination; D005060:Europe; D005544:Forecasting; D006801:Humans; D020767:Intracranial Thrombosis / Q000175:diagnosis* / Q000628:therapy*; D059906:Neuroimaging / Q000592:standards*; D018579:Patient Selection; D015641:Radiography, Interventional; D012107:Research Design / Q000592:standards*; D012955:Societies, Medical; D015607:Stents; D020521:Stroke / Q000175:diagnosis* / Q000628:therapy*; D013673:Technology Assessment, Biomedical; D017131:Thrombectomy / Q000295:instrumentation / Q000379:methods*; D015912:Thrombolytic Therapy / Q000592:standards