title: Effect of hepatitis B virus infection on right and left ventricular functions.
abstract: BACKGROUND
  In this study we examined right and left ventricular systolic functions in hepatitis B virus (HBV) patients.
  
  
  METHODS
  The study included 50 HBsAg-positive patients (mean age; 33±13 years) and 50 other persons (mean age; 28±11 years) as a control group. Transthoracic echocardiography was performed in all the participants. Right and left ventricle systolic parameters were compared between these 2 groups.
  
  
  RESULTS
  In the group of the patients with HBsAg positivity, the right ventricular fractional area change (RV FAC), tricuspid annular plane excursion (TAPSE) and RV myocardial systolic velocity (St) values were lower than in the control group (33±11 vs. 52±13%, p=0.001; 14.6±1.1 vs. 22.2±2.4 mm, p<0.001; 8.6±1.2 vs. 15.8±2.3 cm/s, p<0,001, respectively); the right atrium (RA) and RV diameters were higher than in controls (5.1±1.2 vs. 3.7±0.5 cm, p<0.001; 4.9±0.8 vs. 3.4±0.5 cm p<0.001, respectively); and systolic pulmonary artery pressure was higher than in control (39.3±9.5 vs. 22±8.4 mmHg, p<0.001).
  
  
  CONCLUSIONS
  The findings showed that HBV infection may be associated with right ventricular systolic dysfunction and pulmonary hypertension.
authors.affiliation: Department of Cardiology, Bursa Yuksek Ihtisas Education and Research Hospital, Bursa, Turkey. drmehmetmd@gmail.com
authors.forename: Mehmet
authors.initials: M
authors.lastname: Demir
authors.forename: Canan
authors.initials: C
authors.lastname: Demir
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity; D001794:Blood Pressure; D016022:Case-Control Studies; D004452:Echocardiography; D005260:Female; D006509:Hepatitis B / Q000150:complications / Q000473:pathology*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D014261:Tricuspid Valve / Q000503:physiopathology; D018497:Ventricular Dysfunction, Right / Q000209:etiology / Q000503:physiopathology*; D016277:Ventricular Function, Left / Q000502:physiology*; D016278:Ventricular Function, Right / Q000502:physiology*