title: Probable disseminated Mycobacterium abscessus subspecies bolletii infection in a patient with idiopathic CD4+ T lymphocytopenia: a case report.
abstract: BACKGROUND
  Rapidly growing mycobacteria are opportunistic pathogens in patients with underlying risk factors. Mycobacterium abscessus subsp. bolletii is a newly recognized member of rapidly growing mycobacteria, isolated from respiratory tract and cutaneous infections.
  
  
  METHODS
  We describe a case of chronic disseminated infection caused by M. abscessus subsp. bolletii in a 38-year-old Sri Lankan man with idiopathic CD4+ T lymphocytopenia. Idiopathic CD4+ T lymphocytopenia is a rare cause of immunodysfunction that, similar to human immunodeficiency virus infection, causes a depletion of CD4+ T lymphocytes. M. abscessus subsp. bolletii infection was diagnosed by culture isolation from two sputum samples.
  
  
  CONCLUSIONS
  To the best of our knowledge this is the first report of M. abscessus subsp. bolletii disseminated infection in a patient affected by idiopathic CD4+ T lymphocytopenia. In contrast to previous reports, the isolate of M. abscessus subsp. bolletii presented intermediate resistance to clarithromycin and was susceptible to cefoxitin and imipenem.
authors.affiliation: Dipartimento di Scienze per la Promozione della Salute, Università di Palermo, Via del Vespro 129, Palermo, 90127, Italy. raffaellarubino@libero.it.
authors.forename: Claudia
authors.initials: C
authors.lastname: Colomba
authors.forename: Raffaella
authors.initials: R
authors.lastname: Rubino
authors.forename: Paola
authors.initials: P
authors.lastname: Di Carlo
authors.forename: Caterina
authors.initials: C
authors.lastname: Mammina
authors.forename: Celestino
authors.initials: C
authors.lastname: Bonura
authors.forename: Lucia
authors.initials: L
authors.lastname: Siracusa
authors.forename: Lucina
authors.initials: L
authors.lastname: Titone
authors.forename: Laura
authors.initials: L
authors.lastname: Saporito