title: The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping.
abstract: Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the International Mouse Phenotyping Consortium (IMPC) over the next 10 years is to undertake broad-based phenotyping of 20,000 mouse genes, providing an unprecedented insight into mammalian gene function. This short article explores the drivers for large-scale mouse phenotyping and provides an overview of the aims and processes involved in IMPC mouse production and phenotyping.
authors.affiliation: MRC Mammalian Genetics Unit, MRC Harwell, Oxfordshire OX11 0RD, UK. s.brown@har.mrc.ac.uk
authors.forename: Steve D M
authors.initials: SD
authors.lastname: Brown
authors.forename: Mark W
authors.initials: MW
authors.lastname: Moore
mesh_terms: D000818:Animals; D038622:Internationality; D051379:Mice; D008817:Mice, Mutant Strains; D010641:Phenotype