title: Optical frequency domain imaging system and catheters for volumetric imaging of the human esophagus.
abstract: Barrett's esophagus (BE) is a metaplastic disorder that can undergo dysplastic progression, leading to esophageal adenocarcinoma. Upper endoscopy is the standard of care for screening for BE, but this technique has a relatively low diagnostic accuracy and high cost due to the requirement of conscious sedation. Optical frequency domain imaging (OFDI) is a high-speed imaging modality that generates cross-sectional images of tissues with a resolution of approximately 10μm that is sufficient for detecting microscopic tissue architecture. In combination with a balloon-centering catheter, this method enables BE diagnosis over the entire distal esophagus.
authors.affiliation: Wellman Center for Photomedicine, Massachusetts General Hospital, Boston MA.
authors.forename: Michalina
authors.initials: M
authors.lastname: Gora
authors.forename: Hongki
authors.initials: H
authors.lastname: Yoo
authors.forename: Melissa J
authors.initials: MJ
authors.lastname: Suter
authors.forename: Kevin A
authors.initials: KA
authors.lastname: Gallagher
authors.forename: Brett E
authors.initials: BE
authors.lastname: Bouma
authors.forename: Norman S
authors.initials: NS
authors.lastname: Nishioka
authors.forename: Guillermo J
authors.initials: GJ
authors.lastname: Tearney