title: Ultrasound-guided injection of botulinum toxin A into the submandibular gland in children and young adults with sialorrhoea.
abstract: Hypersalivation is a common and distressing complaint in children with neuromuscular disorders such as cerebral palsy. Complications associated with severe drooling include daily changes of clothing, perioral dermatitis, dental problems, dehydration, and aspiration pneumonia, which potentially have a detrimental effect on the quality of life of the patient and carer. In this paper we update our previous work to show the potential benefits of ultrasound-guided injection of botulinum toxin A (BTX-A) into the submandibular gland and report on new patients and follow-up data on the existing group.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Eastbourne District General Hospital, Kings Drive, Eastbourne, East Sussex BN21 2UD, UK. gulcangok43@hotmail.co.uk
authors.forename: Gulcan
authors.initials: G
authors.lastname: Gok
authors.forename: Natalie
authors.initials: N
authors.lastname: Cox
authors.forename: Jasdeep
authors.initials: J
authors.lastname: Bajwa
authors.forename: Dimitra
authors.initials: D
authors.lastname: Christodoulou
authors.forename: Andrew
authors.initials: A
authors.lastname: Moody
authors.forename: David C
authors.initials: DC
authors.lastname: Howlett
mesh_terms: D000293:Adolescent; D000328:Adult; D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D002547:Cerebral Palsy / Q000150:complications; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D007859:Learning Disabilities / Q000150:complications; D008297:Male; D009465:Neuromuscular Agents / Q000008:administration & dosage*; D011788:Quality of Life; D012798:Sialorrhea / Q000188:drug therapy*; D013363:Submandibular Gland / Q000000981:diagnostic imaging / Q000187:drug effects*; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional; D055815:Young Adult
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A