title: A rare case of Hodkin's lymphoma of the mediastinum imitating retrosternal goiter--retrospective analysis of the diagnostic process.
abstract: Primary extranodal sites of development of lymphoid neoplasms are rare and concern about 5% of patients with Hodgkin's lymphoma. Extranodal development is more common in non Hodgkin's lymphoma and may reach 33%. A 27-year-old woman was diagnosed by a cardiologist for a short breath. On the physical examination no other abnormalities were observed. Echocardiography, performed by cardiologist, revealed a large tumor, overlaying the right ventricle and compressing the pulmonary trunk. Chest X-ray, ultrasound and CT-scan confirmed diagnosis. In fine needle aspiration clear, lucid fluid was obtained. Scintygraphy of the neck and thorax showed accumulation of the marker in the properly placed but enlarged thyroid gland. Patient was qualified for surgical treatment - cervicotomy and sternothomy were performed. The histopatological exam of the tumor revealed Hodgkin's lymphoma of the mediastinum (classical subtype NS-1). Following the surgery, adjuvant therapy was instituted. After the treatment PET-CT-scan did not show any kind of non-physiological radiomarker's accumulation in the monitored regions of the body and in in three-years follow-up the patient shows no signs of recurrence.
authors.affiliation: Department of General, Oncological and Endocrine Surgery, Medical University in Łódź, Polish Mother's Memorial Hospital - Research Institute.
authors.forename: Marek
authors.initials: M
authors.lastname: Dedecjus
authors.forename: Anna
authors.initials: A
authors.lastname: Kędzierska
authors.forename: Józef
authors.initials: J
authors.lastname: Kozak
authors.forename: Radzisław
authors.initials: R
authors.lastname: Kordek
authors.forename: Jan
authors.initials: J
authors.lastname: Brzeziński
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004935:Esophageal Diseases / Q000175:diagnosis; D005260:Female; D006045:Goiter, Substernal / Q000175:diagnosis; D006689:Hodgkin Disease / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008479:Mediastinal Neoplasms / Q000473:pathology* / Q000601:surgery*; D009367:Neoplasm Staging; D035583:Rare Diseases; D016896:Treatment Outcome