title: A new prenylated aurone from Artocarpus altilis.
abstract: Phytochemical study of the methanol extract of Artocarpus altilis resulted in the isolation of a new prenylated aurone, artocarpaurone (1), together with eight known compounds including two prenylated chalcones (2 and 3), three prenylated flavanones (4-6), and three triterpenes (7-9). The structure of 1 was elucidated as 6-hydroxy-2-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-ylmethylene]-3(2H)-benzofuranone by spectroscopic methods including 1D and 2D NMR spectra and FT-ICR-MS. Compound 1 showed moderate nitric oxide radical scavenging activity, whereas 2 and 3 had moderate 2,2-diphenyl-1-picrylhydrazyl radical scavenging effect, compared with the positive control (+)-catechin.
authors.affiliation: School of Chemical Engineering, Hanoi University of Science and Technology (HUST), Hanoi, Vietnam.
authors.forename: Tran Thu
authors.initials: TT
authors.lastname: Huong
authors.forename: Nguyen Xuan
authors.initials: NX
authors.lastname: Cuong
authors.forename: Le Huyen
authors.initials: le H
authors.lastname: Tram
authors.forename: Tran Thuong
authors.initials: TT
authors.lastname: Quang
authors.forename: Le Van
authors.initials: le V
authors.lastname: Duong
authors.forename: Nguyen Hoai
authors.initials: NH
authors.lastname: Nam
authors.forename: Nguyen Tien
authors.initials: NT
authors.lastname: Dat
authors.forename: Phan Thi Thanh
authors.initials: PT
authors.lastname: Huong
authors.forename: Chau Ngoc
authors.initials: CN
authors.lastname: Diep
authors.forename: Phan Van
authors.initials: PV
authors.lastname: Kiem
authors.forename: Chau Van
authors.initials: CV
authors.lastname: Minh
mesh_terms: D031622:Artocarpus / Q000737:chemistry*; D001572:Benzofurans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001713:Biphenyl Compounds / Q000494:pharmacology; D002392:Catechin / Q000494:pharmacology; D015394:Molecular Structure; D010851:Picrates / Q000494:pharmacology
chemical_list: D001572:Benzofurans; D001713:Biphenyl Compounds; D010851:Picrates; C576794:artocarpaurone; C486837:aurone; D002392:Catechin; C004931:1,1-diphenyl-2-picrylhydrazyl