title: Addition of aripiprazole to the clozapine may be useful in reducing anxiety in treatment-resistant schizophrenia.
abstract: There exist many case reports and studies on the antipsychotic augmentation by aripirazole in partial responders to clozapine, the most seem to be finding a slight difference in the PANSS and CGI scores after the aripirazole addition. The results of our report are compatible with those of other studies but, we have found a considerable antianxiety action in both of the cases. The 5HT1A agonism of aripirazole could be hypothesized as mechanism contributing to this effect.
authors.affiliation: Department of Psychiatry, Centre Hospitalier Universitaire Vaudois, Section Eugene Minkowski, Site de Cery, 1008 Prilly, Switzerland.
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Chanachev
authors.forename: Nicolas
authors.initials: N
authors.lastname: Ansermot
authors.forename: Séverine
authors.initials: S
authors.lastname: Crettol Wavre
authors.forename: Ute
authors.initials: U
authors.lastname: Nowotka
authors.forename: Maria-Eleni
authors.initials: ME
authors.lastname: Stamatopoulou
authors.forename: Philippe
authors.initials: P
authors.lastname: Conus
authors.forename: Chin B
authors.initials: CB
authors.lastname: Eap