title: Performance of "VIKIA Malaria Ag Pf/Pan" (IMACCESS®), a new malaria rapid diagnostic test for detection of symptomatic malaria infections.
abstract: BACKGROUND
  Recently, IMACCESS® developed a new malaria test (VIKIA Malaria Ag Pf/Pan™), based on the detection of falciparum malaria (HRP-2) and non-falciparum malaria (aldolase).
  
  
  METHODS
  The performance of this new malaria rapid diagnostic test (RDT) was assessed using 1,000 febrile patients seeking malaria treatment in four health centres in Cambodia from August to December 2011. The results of the VIKIA Malaria Ag Pf/Pan were compared with those obtained by microscopy, the CareStart Malaria™ RDT (AccessBio®) which is currently used in Cambodia, and real-time PCR (as "gold standard").
  
  
  RESULTS
  The best performances of the VIKIA Malaria Ag Pf/Pan™ test for detection of both Plasmodium falciparum and non-P. falciparum were with 20-30 min reading times (sensitivity of 93.4% for P. falciparum and 82.8% for non-P. falciparum and specificity of 98.6% for P. falciparum and 98.9% for non-P. falciparum) and were similar to those for the CareStart Malaria™ test.
  
  
  CONCLUSIONS
  This new RDT performs similarly well as other commercially available tests (especially the CareStart Malaria™ test, used as comparator), and conforms to the World Health Organization's recommendations for RDT performance. It is a good alternative tool for the diagnosis of malaria in endemic areas.
authors.affiliation: Faculty of Pharmacy, Université des Sciences de la Santé, Phnom Penh, Cambodia.
authors.forename: Monidarin
authors.initials: M
authors.lastname: Chou
authors.forename: Saorin
authors.initials: S
authors.lastname: Kim
authors.forename: Nimol
authors.initials: N
authors.lastname: Khim
authors.forename: Sophy
authors.initials: S
authors.lastname: Chy
authors.forename: Sarorn
authors.initials: S
authors.lastname: Sum
authors.forename: Dany
authors.initials: D
authors.lastname: Dourng
authors.forename: Lydie
authors.initials: L
authors.lastname: Canier
authors.forename: Chea
authors.initials: C
authors.lastname: Nguon
authors.forename: Didier
authors.initials: D
authors.lastname: Ménard
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000953:Antigens, Protozoan / Q000097:blood*; D002160:Cambodia; D002648:Child; D002675:Child, Preschool; D003955:Diagnostic Tests, Routine / Q000379:methods*; D005260:Female; D006801:Humans; D007223:Infant; D008288:Malaria / Q000175:diagnosis*; D008297:Male; D008853:Microscopy / Q000379:methods; D008875:Middle Aged; D018512:Parasitemia / Q000175:diagnosis*; D060888:Real-Time Polymerase Chain Reaction / Q000379:methods; D012680:Sensitivity and Specificity; D055815:Young Adult
chemical_list: D000953:Antigens, Protozoan