title: Fetomaternal hemorrhage with intraplacental chorioangioma.
abstract: A 37-year-old Asian woman, gravid 0 para 0, was admitted to our hospital at 34 weeks and 5 days of her pregnancy for management of preeclampsia. A few days after admission, she recognized diminished fetal movement, and a non-stress test revealed a non-reassuring fetal heart rate pattern with decreased variability. A female baby weighing 1840 g was delivered by emergency cesarean section with Apgar scores of 5 and 5 at 1 and 5 min, respectively. Significant neonatal anemia with a hemoglobin level of 4.3 g/dL was observed. The elevated level of hemoglobin F (HbF) in the maternal blood accounted for 4.6% (normal≦0.5%), and was indicative of the presence of fetomaternal hemorrhage (FMH). Microscopic examination of the placenta revealed chorioangioma. We report here a rare case of FMH with intraplacental chorioangioma, and discuss the relationship between these two pathologies.
authors.affiliation: Departments of Obstetrics and Gynecology, Omuta City Hospital, Omuta-shi, Japan. kawano_ryousuke@med.kurume-u.ac.jp
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Kawano
authors.forename: Shuji
authors.initials: S
authors.lastname: Takemoto
authors.forename: Kazuhide
authors.initials: K
authors.lastname: Shimamatsu
authors.forename: Daizo
authors.initials: D
authors.lastname: Hori
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Kamura
mesh_terms: D000328:Adult; D005260:Female; D005331:Fetomaternal Transfusion / Q000209:etiology* / Q000628:therapy; D006391:Hemangioma / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D007231:Infant, Newborn; D050498:Live Birth; D010922:Placenta Diseases / Q000473:pathology / Q000503:physiopathology*; D011225:Pre-Eclampsia / Q000209:etiology; D011247:Pregnancy; D016896:Treatment Outcome