title: U-500 concentrated regular insulin: practical application in the outpatient setting.
abstract: Administering large insulin doses to patients with severely insulin-resistant diabetes is often ineffective, expensive, and painful. U-500 regular insulin is absorbed better, less painful, and more cost-effective due to the reduced volume. This article describes the most recent guidelines for U-500 insulin in the clinical setting.
authors.affiliation: The Ohio State University Medical Center, Division of Endocrinology, Diabetes, and Metabolism, OH, USA.
authors.forename: Sarah
authors.initials: S
authors.lastname: Taylor
mesh_terms: D000553:Ambulatory Care / Q000379:methods*; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage* / Q000737:chemistry; D007328:Insulin / Q000008:administration & dosage* / Q000737:chemistry; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D016896:Treatment Outcome
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin