title: Catheter-based arterial sympathectomy: hypertension and beyond.
abstract: Transluminal ablation of renal artery sympathetic nerves has been shown to provide a significant and durable reduction in blood pressure with very low complication rates. Additional publications have documented improvement in insulin sensitivity, obstructive sleep apnea indices, and frequency and severity of congestive heart failure in subgroups undergoing the procedure. This technology may provide effective management of other diseases in which there is autonomic imbalance. Available data are reviewed with the intent to provoke interest within the interventional radiology community in this novel technology, which may allow minimally invasive treatment of many important chronic medical conditions.
authors.affiliation: Department of Diagnostic Radiology, Brown University, Providence, RI 02903, USA. eprince@lifespan.org
authors.forename: Ethan A
authors.initials: EA
authors.lastname: Prince
authors.forename: Timothy P
authors.initials: TP
authors.lastname: Murphy
authors.forename: Christopher O
authors.initials: CO
authors.lastname: Hampson
mesh_terms: D000818:Animals; D050197:Atherosclerosis / Q000503:physiopathology / Q000601:surgery; D001794:Blood Pressure; D017115:Catheter Ablation; D003920:Diabetes Mellitus / Q000503:physiopathology / Q000601:surgery; D050171:Dyslipidemias / Q000503:physiopathology / Q000601:surgery; D006333:Heart Failure / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D006973:Hypertension / Q000503:physiopathology / Q000601:surgery*; D007333:Insulin Resistance; D009765:Obesity / Q000503:physiopathology / Q000601:surgery; D012077:Renal Artery / Q000294:innervation*; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology / Q000601:surgery; D013562:Sympathectomy / Q000379:methods*; D016896:Treatment Outcome