title: The emergence of phox-ER stress induced immunogenic apoptosis.
abstract: Primary induction of photo-oxidative (phox)-ER stress in cancer cells evoked immunogenic apoptosis (IA) associated with pre-apoptotic emission of calreticulin and ATP, and protective antitumor immunity. This IA subroutine involved "core" functions (e.g., PERK/PI3K-based modulation of secretory trafficking) rather than "private" ones (caspase-8 and eIF2α-phosphorylation) engaged by other IA inducers.
authors.affiliation: Cell Death Research and Therapy Unit; Department for Cellular and Molecular Medicine; University of Leuven (KULeuven); Leuven, Belgium.
authors.forename: Abhishek D
authors.initials: AD
authors.lastname: Garg
authors.forename: Dmitri V
authors.initials: DV
authors.lastname: Krysko
authors.forename: Peter
authors.initials: P
authors.lastname: Vandenabeele
authors.forename: Patrizia
authors.initials: P
authors.lastname: Agostinis