title: A pilot study of pulmonary rehabilitation and chest physiotherapy versus chest physiotherapy alone in bronchiectasis.
abstract: OBJECTIVE
  The aim of our study was to assess the efficacy of pulmonary rehabilitation in addition to regular chest physiotherapy in non cystic fibrosis bronchiectasis.
  
  
  METHODS
  Thirty patients with clinically significant bronchiectasis and limited exercise tolerance were randomized into either the control group receiving chest physiotherapy (8 weeks) or into the intervention group, receiving pulmonary rehabilitation in addition to chest physiotherapy (8 weeks). Both groups were encouraged to maintain their exercise program and or chest physiotherapy, following completion of the study.
  
  
  RESULTS
  End of training (8 weeks) No improvement in control group. In the intervention group, incremental shuttle walk test (ISWT) improved by 56.7 m (p = 0.03), endurance walk test (EWT) by 193.3 m (p = 0.01), Leicester Cough Questionnaire (LCQ) improved by 2.6 units (p < 0.001) and St. George's Respiratory Questionnaire (SGRQ) by 8 units (p < 0.001). At 20 weeks (12 weeks post end of training) No improvement in control group. In the intervention group, ISWT improved by 80 m (p = 0.04) and EWT by 247.5 m (p = 0.003). LCQ improved by 4.4 units (p < 0.001) and SGRQ by 4 units (p < 0.001).
  
  
  CONCLUSIONS
  Pulmonary rehabilitation in addition to regular chest physiotherapy, improves exercise tolerance and health related quality of life in non cystic fibrosis bronchiectasis and the benefit was sustained at 12 weeks post end of pulmonary rehabilitation. Clinical trials regn no. NCT00868075.
authors.affiliation: Centre for Inflammation Research, Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK. pallavimandal@googlemail.com
authors.forename: P
authors.initials: P
authors.lastname: Mandal
authors.forename: M K
authors.initials: MK
authors.lastname: Sidhu
authors.forename: L
authors.initials: L
authors.lastname: Kope
authors.forename: W
authors.initials: W
authors.lastname: Pollock
authors.forename: L M
authors.initials: LM
authors.lastname: Stevenson
authors.forename: J L
authors.initials: JL
authors.lastname: Pentland
authors.forename: K
authors.initials: K
authors.lastname: Turnbull
authors.forename: S
authors.initials: S
authors.lastname: Mac Quarrie
authors.forename: A T
authors.initials: AT
authors.lastname: Hill
mesh_terms: D001987:Bronchiectasis / Q000503:physiopathology / Q000534:rehabilitation*; D003131:Combined Modality Therapy; D005080:Exercise Test; D005081:Exercise Therapy / Q000379:methods; D017079:Exercise Tolerance; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology; D010353:Patient Education as Topic; D010865:Pilot Projects; D012129:Respiratory Function Tests; D012132:Respiratory Muscles / Q000502:physiology; D012138:Respiratory Therapy / Q000379:methods*; D016896:Treatment Outcome