title: Development of a novel universal immune receptor for antigen targeting: To Infinity and beyond.
abstract: Chimeric antigen receptors (CARs) possess fixed specificity for a single antigen and require empirical testing in T cells. To address this, we have developed a novel, adaptable immune receptor strategy that allows for the rapid generation and testing of T cells of nearly infinite antigen specificity.
authors.affiliation: Department of Pathology and Laboratory Medicine; University of Pennsylvania; Philadelphia, PA USA.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Urbanska
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Powell