title: Characterization of structural changes in aptamer films for controlled release nanodevices.
abstract: The dimension of the conformational changes of DNA-aptamers which can be used as stimulus-responsive gate-keepers in controlled delivery nanodevices has been determined by acoustic wave-based sensors upon molecular recognition of a small-sized target, adenosine-5'-monophosphate (AMP).
authors.affiliation: EMaS, Department of Electronic, Electric and Automation Engineering, University Rovira i Virgili, Avda. Països Catalans 26, 43007 Tarragona, Spain. mariabelen.serrano@urv.cat
authors.forename: M Belén
authors.initials: MB
authors.lastname: Serrano-Santos
authors.forename: Eduard
authors.initials: E
authors.lastname: Llobet
authors.forename: Veli C
authors.initials: VC
authors.lastname: Özalp
authors.forename: Thomas
authors.initials: T
authors.lastname: Schäfer
mesh_terms: D000249:Adenosine Monophosphate / Q000737:chemistry / Q000378:metabolism*; D052157:Aptamers, Nucleotide / Q000737:chemistry* / Q000378:metabolism; D003692:Delayed-Action Preparations / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D058525:Quartz Crystal Microbalance Techniques
chemical_list: D052157:Aptamers, Nucleotide; D003692:Delayed-Action Preparations; D000249:Adenosine Monophosphate