title: Comparison of survival of patients receiving laparoscopic and open radical resection for stage II colon cancer.
abstract: BACKGROUND
  The aim of the study was to compare the survival of patients receiving laparoscopic vs. open radical resection for stage II colon cancer.
  
  
  METHODS
  Two hundred and twenty patients with stage II colon cancer were enrolled from Beijing Chaoyang Hospital of Capital Medical University from January 2000 to December 2009, including 61 patients in the laparoscopic radical resection group and 159 patients in the open radical resection group. The survival data in both groups were compared using the log rank test based on Kaplan-Meier survival curves.
  
  
  RESULTS
  There was no statistically significant difference in the 3-year survival (88.5% vs. 80.5%; X(2)=1.98, P=0.159) and the 5-year survival (81.9% vs. 69.2%; X(2)=1.98, P=0.159) between both groups. However, statistically significant difference was found in median overall survival (mOS), which was 102.6 (95% CI: 76.8-122.7) months in the laparoscopic group and 90.0 (95% CI: 70.4-109.6) months in the open radical resection group (X(2)=4.183, P=0.041). mOS was 96 (95% CI: 68.6-111.4) months and 92.6 (95% CI: 56.8-107.2) months in those with and without postoperative chemotherapy, respectively (X(2)=6.389, P=0.011). For patients older than 75 years the mOS was 90.0 (95% CI: 25.3-105.0) months and 83.4 (95% CI: 13.1-96.9) months in the laparoscopic and open group, respectively. The difference between the both groups was statistically significant (X(2)=6.191, P=0.013).
  
  
  CONCLUSIONS
  The mOS of patients receiving laparoscopic radical resection was better than open radical resection for stage II colon cancer, especially for patients over 75 years old.
authors.affiliation: Department of Oncology, Beijing Chaoyang Hospital, Capital University of Medical Science, Beijing, China.
authors.forename: Cui-Zhen
authors.initials: CZ
authors.lastname: Fan
authors.forename: Yu-Ping
authors.initials: YP
authors.lastname: Chu
authors.forename: Ping
authors.initials: P
authors.lastname: Wei
authors.forename: Hong
authors.initials: H
authors.lastname: Dai
authors.forename: Wenming
authors.initials: W
authors.lastname: Chen