title: Comparison of segmental wall motion abnormalities on echocardiography in patients with anteroseptal versus extensive anterior wall ST-segment elevation myocardial infarction.
abstract: OBJECTIVE
  Acute anteroseptal ST-segment elevation (STE) myocardial infarction (AS-STEMI), defined as STE limited to leads V1 to V3, has historically been associated with a smaller infarct size than extensive anterior STEMI (EA-STEMI), in which STE extends to leads V4 to V6. We compared the differences in global and regional wall motion by transthoracic echocardiography between patients with AS-STEMI and EA-STEMI.
  
  
  METHODS
  Patients who presented with anterior STEMI and underwent primary percutaneous coronary intervention between January 2008 and March 2011 were included. For each subject, a transthoracic echocardiogram that was performed within 24 hours of admission was interpreted by an independent investigator blinded to the patient's electrocardiographic data.
  
  
  RESULTS
  Of the 65 subjects who met our inclusion criteria, 30 had AS-STEMI and 35 had EA-STEMI. No differences were observed between groups in baseline characteristics or the mean number of hypokinetic, akinetic, and dyskinetic segments. Apical inferior segment dysfunction occurred more often in patients with EA-STEMI than in patients with AS-ASTEMI (71.4% vs 43.3%; P=.04). Distribution and extent of wall motion abnormalities were similar between patients with AS-STEMI and those with EA-STEMI.
  
  
  CONCLUSIONS
  The term AS-STEMI may be misleading, as it implies that only the anteroseptal segments are involved. We show that regional dysfunction in patients with AS-STEMI extends beyond the anteroseptal region.
authors.affiliation: Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
authors.forename: Salman Jamaluddin
authors.initials: SJ
authors.lastname: Bandeali
authors.forename: Sabrina
authors.initials: S
authors.lastname: Stone
authors.forename: Henry Darchon
authors.initials: HD
authors.lastname: Huang
authors.forename: Waleed Talat
authors.initials: WT
authors.lastname: Kayani
authors.forename: James Michael
authors.initials: JM
authors.lastname: Wilson
authors.forename: Yochai
authors.initials: Y
authors.lastname: Birnbaum
mesh_terms: D004452:Echocardiography / Q000379:methods*; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications* / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000209:etiology*