title: The carbapenem-resistant Enterobacteriaceae score: a bedside score to rule out infection with carbapenem-resistant Enterobacteriaceae among hospitalized patients.
abstract: Patients infected with carbapenem-resistant Enterobacteriaceae often experience delays in initiation of appropriate antimicrobial therapy and increased mortality. A score was developed to differentiate bloodstream infections caused by carbapenem-resistant Enterobacteriaceae (16 patients) versus extended-spectrum β-lactamase-producing Enterobacteriaceae (166 patients). A score of ≥ 32 demonstrated high area under the curve of 0.80 (95% confidence interval: 0.68-0.92) and a negative predictive value of 97%.
authors.affiliation: Department of Pharmacy Practice, Wayne State University, Detroit, MI 48201, USA. etmartin@wayne.edu
authors.forename: Emily T
authors.initials: ET
authors.lastname: Martin
authors.forename: Ryan
authors.initials: R
authors.lastname: Tansek
authors.forename: Vicki
authors.initials: V
authors.lastname: Collins
authors.forename: Kayoko
authors.initials: K
authors.lastname: Hayakawa
authors.forename: Odaliz
authors.initials: O
authors.lastname: Abreu-Lanfranco
authors.forename: Teena
authors.initials: T
authors.lastname: Chopra
authors.forename: Paul R
authors.initials: PR
authors.lastname: Lephart
authors.forename: Jason M
authors.initials: JM
authors.lastname: Pogue
authors.forename: Keith S
authors.initials: KS
authors.lastname: Kaye
authors.forename: Dror
authors.initials: D
authors.lastname: Marchaim
mesh_terms: D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D015780:Carbapenems / Q000494:pharmacology*; D015331:Cohort Studies; D003661:Decision Support Techniques; D004755:Enterobacteriaceae / Q000187:drug effects*; D004756:Enterobacteriaceae Infections / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D011237:Predictive Value of Tests; D018440:beta-Lactam Resistance
chemical_list: D015780:Carbapenems