title: Th17 cell frequency in peripheral blood from children with allergic asthma correlates with the level of asthma control.
abstract: Here we show that the frequency of T(H)17 cells (CD3(+)CD4(+)CD161(+)CCR6(+) lymphocytes) is increased in peripheral blood of children with allergic asthma. Moreover, we found a significant relationship between the frequency of T(H)17 cells and level of asthma control, with reduced asthma control correlated with a higher proportion of T(H)17 cells.
authors.affiliation: Department of Pediatrics, Philipps University, Marburg, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Kerzel
authors.forename: Jana
authors.initials: J
authors.lastname: Dehne
authors.forename: Tobias
authors.initials: T
authors.lastname: Rogosch
authors.forename: Bianca
authors.initials: B
authors.lastname: Schaub
authors.forename: Rolf F
authors.initials: RF
authors.lastname: Maier
authors.forename: Michael
authors.initials: M
authors.lastname: Zemlin
mesh_terms: D000293:Adolescent; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D001249:Asthma / Q000097:blood* / Q000188:drug therapy / Q000473:pathology; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012720:Severity of Illness Index; D058504:Th17 Cells / Q000378:metabolism* / Q000473:pathology
chemical_list: D018927:Anti-Asthmatic Agents; D015415:Biomarkers