title: Hypertriglyceridemic waist may explain ethnic differences in hypertension among patients with type 2 diabetes in Sweden.
abstract: BACKGROUND
  Hypertension is common among persons with type 2 diabetes. The aim of this study was to analyze the association between ethnicity and hypertension prevalence after adjusting for age, sex, Hba1c, total cholesterol, elevated triglycerides and hypertriglyceridemic waist. The study population consisted of 354 primary health care patients diagnosed with type 2 diabetes (173 Assyrians/Syrians and 181 Swedes) residing in Södertälje, Sweden. Unconditional logistic regression was used to analyze the data.
  
  
  RESULTS
  Hypertension prevalence was higher among Swedes than Assyrians/Syrians, (77% versus 58%; p = 0.001). In the unadjusted logistic regression model, the odds ratio for hypertension in Swedes was twice as high than that in Assyrians/Syrians (OR = 2.44; 95% CI =1.54-3.86). In the age- and sex-adjusted model, odds ratio of hypertension was 2.25 (95% CI 1.41-3.60). After adjustments for total cholesterol was made, the odds ratio of hypertension decreased slightly to 1.73. When elevated triglycerides and hypertriglyceridemic waist were separately introduced, the odds ratio of hypertension was no longer significant between the ethnic groups (1.60 and 1.43 for triglycerides and hypertriglyceridemic waist respectively). In addition, advanced age - 60-69 years old (OR = 1.80, CI 95% 1.00-3.20) and ≥ 70 years old (OR = 2.88, CI 95% 1.40-5.93), elevated total cholesterol (OR = 1.48, CI 95% 1.12-1.95) and presents of hypertriglyceridemic waist (those with high WC and high TG) were significant confounding factors for the increased risk of hypertension independent of ethnicity.
  
  
  CONCLUSIONS
  The crude differences in prevalence of hypertension between the Swedes and Assyrians/Syrians in our study population with type 2 diabetes were no longer significant when adjusting for high triglycerides levels or the presence of hypertriglyceridemic waist.
authors.affiliation: Karolinska Institutet, Centre for Family and Community Medicine, Alfred Nobels allé 12, Huddinge, SE 141 83, Sweden. marina.taloyan@sll.se
authors.forename: Marina
authors.initials: M
authors.lastname: Taloyan
authors.forename: Nuha
authors.initials: N
authors.lastname: Saleh-Stattin
authors.forename: Sven-Erik
authors.initials: SE
authors.lastname: Johansson
authors.forename: Lars
authors.initials: L
authors.lastname: Agréus
authors.forename: Per
authors.initials: P
authors.lastname: Wändell
mesh_terms: D000328:Adult; D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000208:ethnology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000208:ethnology*; D015228:Hypertriglyceridemia / Q000150:complications / Q000208:ethnology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D013548:Sweden; D055105:Waist Circumference