title: A synthetic method for palladium-catalyzed stannylation at the 5- and 6-benzo positions of indoles.
abstract: The stannylation of indole derivatives proceeds in good yields under palladium catalysis (5 mol %) without protection of the indolic nitrogen. The general utility of both PdCl(2)(PhCN)(2)/PCy(3) and Pd(2)dba(3)/PCy(3) as catalytic systems for the stannylation of three indole derivatives, with varying degrees of electron density, is presented.
authors.affiliation: Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, USA.
authors.forename: Emily B
authors.initials: EB
authors.lastname: Corcoran
authors.forename: Anna B
authors.initials: AB
authors.lastname: Williams
authors.forename: Robert N
authors.initials: RN
authors.lastname: Hanson
mesh_terms: D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D020650:Combinatorial Chemistry Techniques; D007211:Indoles / Q000737:chemistry*; D015394:Molecular Structure; D009947:Organotin Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D007211:Indoles; D009947:Organotin Compounds; D010165:Palladium