title: Evaluation of the relationship between heart type fatty acid binding protein levels and the risk of maternal cardiac ischemia in low risk obstetric population during delivery.
abstract: OBJECTIVE
  To investigate the heart type fatty acid binding protein (hFABP) changes during delivery in low-risk obstetric population.
  
  
  METHODS
  Pregnant women who are at term and met the inclusion criteria were included the study. Maternal echocardiography, electrocardiography, arterial blood pressure monitoring, CK-MB, serum heart type fatty acid binding protein and troponin I levels were evaluated before and after delivery. Of the total of 100 pregnant women, mean age was 26.7±5, 51 pregnant had vaginal delivery and the remaining 49 had caesarean section.
  
  
  RESULTS
  The h-FABP positivity was detected in nine (9%) subjects after the delivery as compared to values before the delivery (p=0.0035). Troponin levels were 0.013±0.001 before the delivery and 0.025±0.002 after the delivery (p= 0.0001). In the comparison of vaginal and Cesarean deliveries, h-FABP positivity was detected in five of 51 subjects in the vaginal delivery group and four of 49 subjects in the cesarean delivery group (p=0.95). The changes in troponin levels were 0.01 ng/mL (-0.02 to 0.2) in the vaginal delivery group and 0.01ng/mL (-0.07 to 0.06) in the cesarean delivery group (p= 0.24).
  
  
  CONCLUSIONS
  Delivery stress is associated with maternal cardiac damage as evaluated by heart type fatty acid binding protein and troponin. There was no difference between the two delivery routes in the risk of maternal cardiac damage.
authors.affiliation: Department of Obstetrics and Gynecology, Sakarya University, Sakarya,Turkey. dmerminakdemir@yahoo.com
authors.forename: Nermin
authors.initials: N
authors.lastname: Akdemir
authors.forename: Suleyman
authors.initials: S
authors.lastname: Akarsu
authors.forename: Sevgi
authors.initials: S
authors.lastname: Türe
authors.forename: Veciha
authors.initials: V
authors.lastname: Ozlem Akcinar
authors.forename: Ahmet Arif
authors.initials: AA
authors.lastname: Yalcin
authors.forename: Cemil
authors.initials: C
authors.lastname: Bilir
authors.forename: Arif
authors.initials: A
authors.lastname: Serhan Cevrioglu
authors.forename: Selcuk
authors.initials: S
authors.lastname: Ozden
authors.forename: Murat
authors.initials: M
authors.lastname: Yucel
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Yurumez
mesh_terms: D000328:Adult; D002585:Cesarean Section; D036861:Delivery, Obstetric; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins / Q000097:blood*; D005260:Female; D006801:Humans; D017202:Myocardial Ischemia / Q000097:blood* / Q000175:diagnosis; D007744:Obstetric Labor Complications / Q000097:blood* / Q000175:diagnosis; D011247:Pregnancy; D012307:Risk Factors
chemical_list: C493408:FABP3 protein, human; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins