title: Alveolar rhabdomyosarcoma with multiple distal metastases. A case report and review of literature.
abstract: An 18-year-old boy, presented with a history of right hip pain with movement restriction and proptosis of right eye. There was severe anaemia, febrile neutropaenia and bleeding manifestations. CT scan of right orbit documented a retro orbital mass. MRI revealed a mass on right side of the pelvis with metastatic deposits in spine. Biopsy from that mass revealed alveolar rhabdomyosarcoma. Bone marrow biopsy showed sarcomatous involvement with decrease in all three cell lineages. Chemotherapy was started according to standard protocol. We lost the patient after 3 weeks of initiation of chemotherapy. In our case, the unusual primary site and presentation with multiple distal metastases makes this case stand apart and therefore worth reporting.
authors.affiliation: Department of General Medicine, North Bengal Medical College, Darjeeling, West Bengal, India. [corrected].
authors.forename: Debojyoti
authors.initials: D
authors.lastname: Sarkar
authors.forename: Sayantan
authors.initials: S
authors.lastname: Ray
authors.forename: Manjari
authors.initials: M
authors.lastname: Saha
authors.forename: Prantar
authors.initials: P
authors.lastname: Chakrabarti
authors.forename: Prantari
authors.initials: P
authors.lastname: Chakrabarti
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D019046:Bone Marrow Neoplasms / Q000473:pathology* / Q000556:secondary* / Q000628:therapy; D059248:Chemoradiotherapy / Q000009:adverse effects; D018450:Disease Progression; D017809:Fatal Outcome; D006801:Humans; D008159:Lumbar Vertebrae / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009918:Orbital Neoplasms / Q000473:pathology* / Q000556:secondary* / Q000628:therapy; D010386:Pelvic Neoplasms / Q000473:pathology* / Q000628:therapy; D018232:Rhabdomyosarcoma, Alveolar / Q000473:pathology* / Q000556:secondary* / Q000628:therapy; D013125:Spinal Neoplasms / Q000473:pathology* / Q000556:secondary* / Q000628:therapy