title: Highly sensitive ratiometric fluorescent chemosensor for silver ion and silver nanoparticles in aqueous solution.
abstract: A pyrene derivative chemosensor (Pyr-WH) based on a dipeptide shows a highly sensitive ratiometric response to Ag(I) as well as silver nanoparticles in aqueous solution at physiological pH. Pyr-WH penetrated live HeLa cells and exhibits a ratiometric response to intracellular Ag(I). The binding mode of Pyr-WH with Ag(I) was characterized based on fluorescence changes in different pH, NMR, and ESI mass spectrometer experiments.
authors.affiliation: Bioorganic Chemistry Laboratory, Department of Chemistry, Inha University, Yunghyun-dong, Nam-gu, Incheon, 402-751, Republic of Korea.
authors.forename: Sujung
authors.initials: S
authors.lastname: Jang
authors.forename: Ponnaboina
authors.initials: P
authors.lastname: Thirupathi
authors.forename: Lok Nath
authors.initials: LN
authors.lastname: Neupane
authors.forename: Junho
authors.initials: J
authors.lastname: Seong
authors.forename: Hyunsook
authors.initials: H
authors.lastname: Lee
authors.forename: Wan In
authors.initials: WI
authors.lastname: Lee
authors.forename: Keun-Hyeung
authors.initials: KH
authors.lastname: Lee
mesh_terms: D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D053758:Nanoparticles / Q000032:analysis*; D011721:Pyrenes / Q000138:chemical synthesis* / Q000737:chemistry; D012834:Silver / Q000032:analysis*; D012996:Solutions / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D011721:Pyrenes; D012996:Solutions; D014867:Water; D012834:Silver