title: Complete genome sequence of an avian-origin H3N2 canine influenza A virus isolated in farmed dogs in southern China.
abstract: We report here the complete genomic sequence of an avian-origin H3N2 canine influenza A virus containing multiple mutations in farmed dogs in southern China. Phylogenetic analyses of the sequences of all eight viral RNA segments demonstrated that these are wholly avian influenza viruses of the Asia lineage. To our knowledge, this is the first report of interspecies transmission of an avian H3N2 influenza virus to domestic farm dogs under natural conditions in Southern China. The amino acid information provided herein suggests that continued study is required to determine if this virus could be established in the farm dog population and pose potential threats to public health.
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, China.
authors.forename: Shuo
authors.initials: S
authors.lastname: Su
authors.forename: Nan
authors.initials: N
authors.lastname: Cao
authors.forename: Jidang
authors.initials: J
authors.lastname: Chen
authors.forename: Furong
authors.initials: F
authors.lastname: Zhao
authors.forename: Huatao
authors.initials: H
authors.lastname: Li
authors.forename: Mingxi
authors.initials: M
authors.lastname: Zhao
authors.forename: Yanjing
authors.initials: Y
authors.lastname: Wang
authors.forename: Zhen
authors.initials: Z
authors.lastname: Huang
authors.forename: Liguo
authors.initials: L
authors.lastname: Yuan
authors.forename: Heng
authors.initials: H
authors.lastname: Wang
authors.forename: Guihong
authors.initials: G
authors.lastname: Zhang
authors.forename: Shoujun
authors.initials: S
authors.lastname: Li
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000821:virology; D002681:China; D004283:Dog Diseases / Q000635:transmission / Q000821:virology; D004285:Dogs; D016679:Genome, Viral; D053122:Influenza A Virus, H3N2 Subtype / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D008969:Molecular Sequence Data; D009154:Mutation; D009976:Orthomyxoviridae Infections / Q000635:transmission / Q000662:veterinary / Q000821:virology