title: Iron deficiency anemia in heart failure.
abstract: Anemia and iron deficiency are quite prevalent in patients with heart failure (HF) and may overlap. Both anemia and iron deficiency are associated with worse symptoms and adverse clinical outcomes. In the past few years, there has been an enormous interest in the subject of iron deficiency and its management in patients with HF. In this review, the etiology and relevance of iron deficiency, iron metabolism in the setting of HF, studies on iron supplementation in patients with HF and potential cardiovascular effects of subclinical iron overload are discussed.
authors.affiliation: Detroit Medical Center, Wayne State University, Detroit, MI, USA.
authors.forename: Natasha P
authors.initials: NP
authors.lastname: Arora
authors.forename: Jalal K
authors.initials: JK
authors.lastname: Ghali
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology* / Q000378:metabolism; D019317:Evidence-Based Medicine; D006333:Heart Failure / Q000150:complications*; D006801:Humans; D007262:Infusions, Intravenous; D058085:Iron Compounds / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D000090463:Iron Deficiencies; D015995:Prevalence; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology
chemical_list: D058085:Iron Compounds