title: [Toxoplasmosis in HIV infection: invasion reactivation criteria].
abstract: Contemporary representation of toxoplasmosis reactivation criteria in HIV infection is generalized. Significance of the issue is justified: toxoplasmosis is a leading neurological pathology in AIDS with a high lethality percentage due to complexity of clinical confirmation and difficulties of laboratory confirmation of the start of reactivation. Clinical, instrumental, immunologic, molecular genetic invasion reactivation criteria are discussed in the article and analysis of their effectiveness is performed; their most feasible combinations are justified. Further system analysis of the cerebral toxoplasmosis reactivation criteria specified in the article in combination with search of new pathogen dissemination markers will allow to obtain important information that has both fundamental interest and important practical significance.
authors.forename: D B
authors.initials: DB
authors.lastname: Goncharov
authors.forename: E V
authors.initials: EV
authors.lastname: Gubareva
authors.forename: N V
authors.initials: NV
authors.lastname: Kobets
authors.forename: E A
authors.initials: EA
authors.lastname: Domonova
authors.forename: E S
authors.initials: ES
authors.lastname: Ievleva
mesh_terms: D000913:Antibodies, Protozoan / Q000097:blood* / Q000276:immunology; D015415:Biomarkers / Q000032:analysis; D018791:CD4 Lymphocyte Count; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology / Q000473:pathology; D060085:Coinfection; D006678:HIV / Q000502:physiology; D015658:HIV Infections / Q000097:blood / Q000276:immunology / Q000821:virology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology; D008279:Magnetic Resonance Imaging; D016053:RNA, Protozoan / Q000097:blood*; D012008:Recurrence; D014122:Toxoplasma / Q000472:pathogenicity* / Q000502:physiology; D016781:Toxoplasmosis, Cerebral / Q000097:blood / Q000175:diagnosis* / Q000276:immunology / Q000469:parasitology*
chemical_list: D000913:Antibodies, Protozoan; D015415:Biomarkers; D007074:Immunoglobulin G; D016053:RNA, Protozoan