title: The selective synthesis of metallanucleosides and metallanucleotides: a new tool for the functionalization of nucleic acids.
abstract: Nucleobases team up: the efficient and selective preparation of purine-derived metallanucleosides, metallanucleotides, and metalladinucleotides having M-C bonds (M=Ir(III), Rh(III)) is reported for the first time. The results presented may be applied to the synthesis of functionalized nucleic acids, or DNA/RNA-modified segments.
authors.affiliation: Departamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense, Madrid, Spain.
authors.forename: Mamen
authors.initials: M
authors.lastname: Martín-Ortíz
authors.forename: Mar
authors.initials: M
authors.lastname: Gómez-Gallego
authors.forename: Carmen
authors.initials: C
authors.lastname: Ramírez de Arellano
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Sierra
mesh_terms: D020029:Base Pairing; D001483:Base Sequence; D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry*; D007495:Iridium / Q000737:chemistry*; D008670:Metals / Q000737:chemistry*; D009696:Nucleic Acids / Q000138:chemical synthesis* / Q000737:chemistry*; D011684:Purine Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry*; D011685:Purine Nucleotides / Q000138:chemical synthesis* / Q000737:chemistry*; D012313:RNA / Q000138:chemical synthesis* / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*
chemical_list: D008670:Metals; D009696:Nucleic Acids; D011684:Purine Nucleosides; D011685:Purine Nucleotides; D007495:Iridium; D012313:RNA; D004247:DNA; D012238:Rhodium