title: TRFolder-W: a web server for telomerase RNA structure prediction in yeast genomes.
abstract: TRFolder-W is a web server capable of predicting core structures of telomerase RNA (TR) in yeast genomes. TRFolder is a command-line Python toolkit for TR-specific structure prediction. We developed a web-version built on the django web framework, leveraging the work done previously, to include enhancements to increase flexibility of usage. To date, there are five core sub-structures commonly found in TR of fungal species, which are the template region, downstream pseudoknot, boundary element, core-closing stem and triple helix. The aim of TRFolder-W is to use the five core structures as fundamental units to predict potential TR genes for yeast, and to provide a user-friendly interface. Moreover, the application of TRFolder-W can be extended to predict the characteristic structure on species other than fungal species.
  
  
  BACKGROUND
  The web server TRFolder-W is available at http://rna-informatics.uga.edu/?f=software&p=TRFolder-w.
authors.affiliation: Institute of Bioinformatics, University of Georgia, Athens, GA 30602, USA.
authors.forename: Dong
authors.initials: D
authors.lastname: Zhang
authors.forename: Xingran
authors.initials: X
authors.lastname: Xue
authors.forename: Russell L
authors.initials: RL
authors.lastname: Malmberg
authors.forename: Liming
authors.initials: L
authors.lastname: Cai
mesh_terms: D016681:Genome, Fungal; D020407:Internet; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry*; D012984:Software; D019098:Telomerase / Q000737:chemistry*; D015003:Yeasts / Q000235:genetics*
chemical_list: C422952:telomerase RNA; D012313:RNA; D019098:Telomerase