title: The self-assembly and aqueous solubilization of [60]fullerene with disaccharides.
abstract: Solubilization of [60]fullerene in water by complexation with disaccharides in mixed homogeneous solvent system, is described for the first time. The complexation of extremely water-insoluble [60]fullerene dissolved in non-polar solvent toluene and extremely water-soluble disaccharides dissolved in polar solvent DMSO resulted in an unique self-assembled highly crystalline water-soluble [60]fullerene-disaccharide complex. The interaction between [60]fullerene and disaccharides was found to be non-covalent and were characterized by FTIR, UV-Vis, NMR, XRD, and thermogravimetric analysis. The particle size of the lactose-C(60) complex was found to be monodisperse ~60 nm from Transmission Electron Microscopy (TEM) and matched with the size obtained from Static Light Scattering (SLS). Preliminary studies of radical scavenging on the most stable free radical 2,2'-diphenyl-1-picrylhydrazyl (DDPH) suggested that complex has potential biological applications.
authors.affiliation: Applied Chemistry Department, Faculty of Technology and Engineering, The MS University of Baroda, Vadodara, India.
authors.forename: Vinod I
authors.initials: VI
authors.lastname: Bhoi
authors.forename: S
authors.initials: S
authors.lastname: Kumar
authors.forename: C N
authors.initials: CN
authors.lastname: Murthy
mesh_terms: D004187:Disaccharides / Q000737:chemistry*; D016166:Free Radical Scavengers / Q000737:chemistry*; D037741:Fullerenes / Q000737:chemistry*; D055772:Green Chemistry Technology; D007700:Kinetics; D012995:Solubility; D014867:Water / Q000737:chemistry*
chemical_list: D004187:Disaccharides; D016166:Free Radical Scavengers; D037741:Fullerenes; D014867:Water; C069837:fullerene C60