title: [Diabetes mellitus and osteoporosis. Cross talk between bone and other internal organs on lifestyle-related disease].
abstract: Mounting evidence revealed that various organs form a regulatory network with each other to maintain whole body homeostasis. Bone is not the exception : neurons and neurotransmitters, including sympathetic nervous system and serotonin, are intimately involved in bone remodeling. Osteoclacin regulates glucose metabolism and male fertility. Moreover, a recent report demonstrated that bone is a target organ of insulin. Thus, bone is now considered as a major player for the whole body homeostasis.
authors.affiliation: Division Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University, School of Medicine, Japan.
authors.forename: Shu
authors.initials: S
authors.lastname: Takeda
mesh_terms: D048909:Diabetes Complications / Q000378:metabolism*; D006706:Homeostasis; D006801:Humans; D007328:Insulin / Q000378:metabolism; D008019:Life Style; D010024:Osteoporosis / Q000378:metabolism*; D012701:Serotonin / Q000378:metabolism
chemical_list: D007328:Insulin; D012701:Serotonin