title: Hypolipidemic applications of microcrystalline cellulose composite synthesized from different agricultural residues.
abstract: Microcrystalline cellulose was prepared from bean hull, rice straw and rice hull. The use of rice hull and rice straw pulp in different proportions as a source of silica to prepare silicified microcrystalline cellulose was investigated. Preparations of microcrystalline cellulose-potato starch composites with different potato starch concentrations were performed. All samples were characterized through various techniques. Physical and mechanical properties of the prepared tablets were tested. The biological activities of one composite was tested in a hyperlipidemic rat model and compared to orlistat to assess its antilipidemic potential. This composite exhibited remarkable antilipidemic effect with decreased insulin sensitivity.
authors.affiliation: Cellulose and Paper Department, National Research Centre, EL-Bohoth Street, Dokki, Cairo 12622, Egypt. abeermadel2003@yahoo.com
authors.forename: Abeer M
authors.initials: AM
authors.lastname: Adel
authors.forename: Nashwa A
authors.initials: NA
authors.lastname: El-shinnawy
mesh_terms: D000383:Agriculture; D000818:Animals; D002482:Cellulose / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D060326:Chemistry Techniques, Synthetic; D004032:Diet; D000960:Hypolipidemic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D008297:Male; D051381:Rats; D012825:Silicon / Q000737:chemistry; D011198:Solanum tuberosum / Q000737:chemistry*; D013213:Starch / Q000737:chemistry*
chemical_list: D000960:Hypolipidemic Agents; D002482:Cellulose; D013213:Starch; C109691:microcrystalline cellulose; D012825:Silicon