title: [Dietary risk factors in relation to colorectal adenoma].
abstract: OBJECTIVE
  The role of dietary risk factors in colorectal carcinogenesis remains unclear. We investigated the association between dietary intakes and colorectal adenomas who visited a health promotion center for a routine health check-up colonoscopy.
  
  
  METHODS
  We conducted a retrospective case-control study using data from individuals who had colonoscopy at Seoul National University Hospital Healthcare System Gangnam Center from October 2003 to December 2007. The subjects were 242 patients (162 males and 80 females) with histopathologically confirmed colorectal adenoma, and 464 (272 males and 192 females) controls. Dietary data were obtained via 24 hour dietary recall, assisted by a registered dietitian. The student's t-test and the chi-square test were performed for the statistical comparison of means and proportions among groups. Multivariate analyses using logistic regression were performed to assess the relation between dietary intake and colorectal adenoma.
  
  
  RESULTS
  The total average energy intake of the patients (male: 2,407.5±429.2 kcal, female: 1,901.3±316.9 kcal) was higher than the controls (male: 2,249.6±430.4 kcal, female: 1,752.4±275.0 kcal; p=0.001). High energy intake (male: OR=4.13, 95% CI=1.70-10.05, p=0.002; female: OR=4.00, 95% CI=1.51-10.61, p=0.005) and animal protein intake (male: OR=3.97, 95% CI=1.66-9.49, p=0.002; female: OR=5.76, 95% CI=1.99-16.169, p=0.001) were found to be associated with the risk of colorectal adenoma after adjusting for confounders such as age, BMI, waist circumference, metabolic syndrome and smoking.
  
  
  CONCLUSIONS
  In summary, high energy intake and animal protein were associated with colorectal adenoma.
authors.affiliation: Department of Internal Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Gangnam Finance Center, 152 Teheran-ro, Gangnam-gu, Seoul 135-984, Korea.
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Yang
authors.forename: Young Sun
authors.initials: YS
authors.lastname: Kim
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Song
authors.forename: Su Jin
authors.initials: SJ
authors.lastname: Chung
authors.forename: In Hee
authors.initials: IH
authors.lastname: Lee
authors.forename: Kyoung Ju
authors.initials: KJ
authors.lastname: Hong
authors.forename: Eun Jung
authors.initials: EJ
authors.lastname: Lee
authors.forename: Dong Hee
authors.initials: DH
authors.lastname: Kim
authors.forename: Jeong Yoon
authors.initials: JY
authors.lastname: Yim
authors.forename: Min Jung
authors.initials: MJ
authors.lastname: Park
authors.forename: Seon Hee
authors.initials: SH
authors.lastname: Lim
authors.forename: Joo Sung
authors.initials: JS
authors.lastname: Kim
mesh_terms: D000236:Adenoma / Q000150:complications / Q000175:diagnosis*; D000367:Age Factors; D000428:Alcohol Drinking; D015992:Body Mass Index; D016022:Case-Control Studies; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000150:complications / Q000175:diagnosis*; D004032:Diet; D004044:Dietary Proteins; D002149:Energy Intake; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications; D008875:Middle Aged; D016017:Odds Ratio; D012189:Retrospective Studies; D012307:Risk Factors; D012907:Smoking; D055105:Waist Circumference
chemical_list: D004044:Dietary Proteins