title: Target-triggered deprotonation of 6-hydroxyindole-based BODIPY: specially switch on NIR fluorescence upon selectively binding to Zn2+.
abstract: Based on 6-hydroxyindole BODIPY with a Schiff-base structure, NIR fluorescence with impressively high selectivity is triggered by deprotonation of the phenol group upon binding with Zn(2+) due to the chelation-enhanced fluorescence effect, thus realizing a promising application in bioimaging of Zn(2+).
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, East China University of Science & Technology, Shanghai 200237, PR China.
authors.forename: Jian
authors.initials: J
authors.lastname: Cao
authors.forename: Chunchang
authors.initials: C
authors.lastname: Zhao
authors.forename: Xuzhe
authors.initials: X
authors.lastname: Wang
authors.forename: Yanfen
authors.initials: Y
authors.lastname: Zhang
authors.forename: Weihong
authors.initials: W
authors.lastname: Zhu
mesh_terms: D001896:Boron Compounds / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D007211:Indoles / Q000737:chemistry*; D061986:MCF-7 Cells; D018613:Microscopy, Confocal; D011522:Protons; D015032:Zinc / Q000737:chemistry*
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D005456:Fluorescent Dyes; D006576:Heterocyclic Compounds, 4 or More Rings; D007211:Indoles; D011522:Protons; C571206:6-hydroxyindole; D015032:Zinc