title: Malignant disease in renal transplant recipients--our experience.
abstract: Kidney transplantation is a treatment of choice for patient with end stage renal disease. Chronic renal failure is characterized with weak cellular and humoral immunity. In our paper we present our experience with presence of malignancy in renal transplant patients. Urology clinic in Belgrade transplanted 411 patients over the period of 16 years. Living donor transplantation was performed for 272 and cadaveric kidney transplant for 139 patients. In the postoperative follow up, malignancies were diagnosed in 7 of the transplanted patients. Three patients developed basal cell skin carcinoma, one was diagnosed with adenocarcinoma of the transplanted kidney, one developed transitional cell carcinoma of the bladder and testicular tumors were diagnosed in two patients. Postoperative immunosuppressive therapy usually double or triple when patients are in the immunological high risk group. Incidence of malignancy according to big health centers is around 1 in every 1000 transplanted patients. It is also noted the rise of incidence of malignancies in transplanted patient in over 50%.
authors.affiliation: Clinical center of Serbia, Urology clinic, Belgrade.
authors.forename: Radmila
authors.initials: R
authors.lastname: Blagojević-Lazić
authors.forename: Dragana
authors.initials: D
authors.lastname: Radivojević
authors.forename: Vladan
authors.initials: V
authors.lastname: Andrejević
authors.forename: Zoran
authors.initials: Z
authors.lastname: Dzamić
authors.forename: Miodrag
authors.initials: M
authors.lastname: Acimović
authors.forename: Drago
authors.initials: D
authors.lastname: Milutinović
authors.forename: Ljubomir
authors.initials: L
authors.lastname: Djurasić
authors.forename: Jovan
authors.initials: J
authors.lastname: Hadzi-Djokić
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D006801:Humans; D007165:Immunosuppression Therapy; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D008875:Middle Aged; D009369:Neoplasms / Q000209:etiology*; D055815:Young Adult