title: Human pluripotent stem cells: applications and challenges in neurological diseases.
abstract: The ability to generate human pluripotent stem cells (hPSCs) holds great promise for the understanding and the treatment of human neurological diseases in modern medicine. The hPSCs are considered for their in vitro use as research tools to provide relevant cellular model for human diseases, drug discovery, and toxicity assays and for their in vivo use in regenerative medicine applications. In this review, we highlight recent progress, promises, and challenges of hPSC applications in human neurological disease modeling and therapies.
authors.affiliation: Stem Cell Research Laboratory, Department of Obstetrics and Gynecology, Geneva University Hospitals Geneva, Switzerland.
authors.forename: Youssef
authors.initials: Y
authors.lastname: Hibaoui
authors.forename: Anis
authors.initials: A
authors.lastname: Feki