title: Intercepted Decarboxylative Allylations of Nitroalkanoates.
abstract: Using palladium-catalyzed decarboxylation, several cascade reactions of allyl and prenyl nitroalkanoates that lead to nitro-containing chemical building blocks are described. A nitronate Michael addition/Tsuji-Trost allylation cascade was developed, leading to functionally dense chemical building blocks. Likewise, a Tsuji-Trost/decarboxylative protonation sequence was developed for the synthesis of orthogonally functionalized 2° nitroalkanes. The latter method provides rapid access to the indolizidine core.
authors.affiliation: The University of Kansas, Department of Chemistry 2010 Malott Hall, 1251 Wescoe Hall Dr., Lawrence, KS, 66045.
authors.forename: Meghan
authors.initials: M
authors.lastname: Schmitt
authors.forename: Alexander J
authors.initials: AJ
authors.lastname: Grenning
authors.forename: Jon A
authors.initials: JA
authors.lastname: Tunge