title: Long-term outcomes after ROLL lumpectomy.
abstract: BACKGROUND
  Occult breast lesions are being successfully targeted by means of Radioactive-guided Occult Lesion Localization (ROLL). Several reports demonstrate suitability of ROLL technique to excise non-palpable breast lesions with immediate advantages.
  
  
  OBJECTIVE
  Evaluation of long-term outcomes after ROLL guided lumpectomy for early breast cancer.  MATERIALS AND METHODS A CONSECUTIVE SERIES OF NON PALPABLE EARLY INVASIVE BREAST CANCERS EXCISED WITH ROLL (151 PTS; DECEMBER 2002#ENTITYSTARTX02013;JUNE 2006) WERE FOLLOWED UP FOR LONG-TERM OUTCOMES, I.E. LOCAL AND/OR SYSTEMIC RECURRENCE. OUR FOLLOW-UP PROTOCOL INCLUDED 6 MONTHLY PHYSICIAN ADMINISTERED CLINICAL EXAMINATIONS AND 18 MONTHLY IMAGING, I.E. MAMMOGRAM. BONE SCAN, LIVER AND BRAIN IMAGING WERE REQUESTED ON CLINICAL NEED. CLINICAL AND/OR RADIOLOGICAL SUSPICIOUS LESIONS FOR LOCAL RECURRENCE WERE CONFIRMED PATHOLOGICALLY:
  
  
  RESULTS
  The median follow-up was 46 months with all patients having a minimum 22 months follow-up. 3/151 local recurrences occurred (1.98%).
  
  
  CONCLUSIONS
  Long-term outcomes, i.e. local recurrence of invasive breast cancer excised with ROLL guidance compares well with existing localization techniques.
authors.forename: H S J
authors.initials: HS
authors.lastname: Ramesh
authors.forename: S
authors.initials: S
authors.lastname: Anguille
authors.forename: S
authors.initials: S
authors.lastname: Poonawala
authors.forename: O
authors.initials: O
authors.lastname: Harris
authors.forename: S
authors.initials: S
authors.lastname: Desmond
authors.forename: R
authors.initials: R
authors.lastname: Thind
authors.forename: L S
authors.initials: LS
authors.lastname: Chagla
authors.forename: R A
authors.initials: RA
authors.lastname: Audisio