title: Genetic heterogeneity and recombination in human type 2 astroviruses.
abstract: Novel lineages of human astrovirus (HAstV) types 2, 2c, and 2d have been identified. Upon sequencing of the 3' end of the genome, the type 2c and 2d HAstVs were found to be open reading frame 1b (ORF1b)-ORF2 recombinant, with ORF1b being derived from type 3 and type 1 HAstVs, respectively. An ORF2 interlineage recombinant strain, 2c/2b, was also identified.
authors.affiliation: Dipartimento di Scienze per la Promozione della Salute G. D'Alessandro, Università di Palermo, Palermo, Italy.
authors.forename: S
authors.initials: S
authors.lastname: De Grazia
authors.forename: M C
authors.initials: MC
authors.lastname: Medici
authors.forename: P
authors.initials: P
authors.lastname: Pinto
authors.forename: P
authors.initials: P
authors.lastname: Moschidou
authors.forename: F
authors.initials: F
authors.lastname: Tummolo
authors.forename: A
authors.initials: A
authors.lastname: Calderaro
authors.forename: F
authors.initials: F
authors.lastname: Bonura
authors.forename: K
authors.initials: K
authors.lastname: Banyai
authors.forename: G M
authors.initials: GM
authors.lastname: Giammanco
authors.forename: V
authors.initials: V
authors.lastname: Martella
mesh_terms: D016000:Cluster Analysis; D018740:Genetic Heterogeneity; D006801:Humans; D001257:Mamastrovirus / Q000145:classification* / Q000235:genetics*; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA
chemical_list: D012367:RNA, Viral