title: [Treatment of hemodialysis catheter-associated bacteremia due to methicillin-resistant Staphylococcus aureus by daptomycin lock method].
abstract: Treatment of catheter-associated infections caused by Staphylococcus aureus is difficult without catheter removal, because of the biofilm formation and its high virulence. In this report, we presented our clinical and microbiological experience with systemic daptomycin (6 mg/kg/on alternate days IV) as well as antibiotic lock therapy (filling of the catheter lumen with 3.5 mg/ml daptomycin together with 0.045 mg/ml calcium) in the treatment of a catheter-associated bloodstream infection caused by methicillin-resistant S.aureus in a patient with hemodialysis catheter which could not be removed.
authors.affiliation: Ondokuz Mayıs University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Samsun, Turkey. hyilmaz@omu.edu.tr
authors.forename: Hava
authors.initials: H
authors.lastname: Yılmaz
authors.forename: Esmeray
authors.initials: E
authors.lastname: Mutlu Yılmaz
authors.forename: Saban
authors.initials: S
authors.lastname: Esen
authors.forename: Mustafa
authors.initials: M
authors.lastname: Sünbül
authors.forename: Hakan
authors.initials: H
authors.lastname: Leblebicioğlu
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D016470:Bacteremia / Q000188:drug therapy* / Q000382:microbiology; D055499:Catheter-Related Infections / Q000188:drug therapy* / Q000382:microbiology; D017576:Daptomycin / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects / Q000295:instrumentation; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D017576:Daptomycin