title: Screening for bipolar disorder in adolescents with the mood disorder questionnaire-adolescent version (MDQ-A) and the child bipolar questionnaire (CBQ).
abstract: OBJECTIVE
  Screening instruments for bipolar disorders (BDs) in children and adolescents have been developed recently. The present study examined performances of the French versions of the mood disorder questionnaire-adolescent version (MDQ-A) and child bipolar questionnaire (CBQ) in a sample of in- and outpatients.
  
  
  METHODS
  Seventy-six adolescents (age 13-18) and parents first completed the MDQ-A (adolescent and parent versions) and CBQ screening instruments. About 3 weeks later, they had a diagnostic interview with the Kiddie-schedule for affective disorders and schizophrenia-present and lifetime (K-SADS-PL), and the adolescent MDQ-A self-report was completed a second time.
  
  
  RESULTS
  Eight of 76 patients (10.5%) met K-SADS-PL diagnostic criteria for BD. Test-retest reliability of the adolescent MDQ-A self-report was moderate (kappa = 0.66), whereas agreement between adolescent and parent reports was poor (kappa = 0.07). Sensitivity and specificity of the MDQ-A with respect to K-SADS-PL were 75.0% and 57.4% for the adolescent version, and 87.5% and 63.2% for the parent version. Corresponding figures were 50.0% and 73.5% for the CBQ. All three screening instruments had low positive predictive values (17.1% for the MDQ-A adolescent version; 21.9% for the MDQ-A parent version; 18.2% for the CBQ), whereas negative predictive values were higher than 90%.
  
  
  CONCLUSIONS
  The present study points to modest performances of the MDQ-A and CBQ to detect BDs in adolescents, with diagnostic criteria for BD being unmet for a majority of patients who screened positive.
authors.affiliation: Office Médico-Pédagogique, Geneva University Hospital, Geneva, Switzerland.
authors.forename: Melissa
authors.initials: M
authors.lastname: Miguez
authors.forename: Béatrice
authors.initials: B
authors.lastname: Weber
authors.forename: Martin
authors.initials: M
authors.lastname: Debbané
authors.forename: Dario
authors.initials: D
authors.lastname: Balanzin
authors.forename: Marianne
authors.initials: M
authors.lastname: Gex-Fabry
authors.forename: Fulvia
authors.initials: F
authors.lastname: Raiola
authors.forename: Rémy P
authors.initials: RP
authors.lastname: Barbe
authors.forename: Marylène
authors.initials: M
authors.lastname: Vital Bennour
authors.forename: François
authors.initials: F
authors.lastname: Ansermet
authors.forename: Stephan
authors.initials: S
authors.lastname: Eliez
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Aubry
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior / Q000523:psychology*; D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis*; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008297:Male; D010290:Parents / Q000523:psychology; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires