title: Growth hormone therapy in Turner syndrome.
abstract: Short stature is the single most common physical abnormality in Turner syndrome (TS) with adult stature averaging 20 cm shorter than that of the general population. Randomized, placebo-controlled studies to final adult height have proven that GH therapy is effective in increasing stature in TS. Recently, randomized, controlled studies have demonstrated that adjunctive therapies with low-dose estrogen or low-dose oxandrolone enhance stature further. These therapies may provide benefits beyond height augmentation.
authors.affiliation: Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7032, USA. mld@med.unc.edu
authors.forename: Marsha L
authors.initials: ML
authors.lastname: Davenport
mesh_terms: D045930:Anabolic Agents / Q000627:therapeutic use; D001827:Body Height / Q000187:drug effects*; D002648:Child; D004359:Drug Therapy, Combination; D004967:Estrogens / Q000627:therapeutic use*; D005260:Female; D013006:Growth Hormone / Q000627:therapeutic use*; D006728:Hormones / Q000627:therapeutic use; D006801:Humans; D010074:Oxandrolone / Q000627:therapeutic use*; D014424:Turner Syndrome / Q000188:drug therapy*
chemical_list: D045930:Anabolic Agents; D004967:Estrogens; D006728:Hormones; D010074:Oxandrolone; D013006:Growth Hormone