title: The relationship between depression and cognitive deficits.
abstract: In the last years cognitive impairment in depression has been widely reported. It is clear that cognitive symptoms persist after remission of psychopathological symptoms but little is known about the pathophysiological events linking depression and cognitive impairment. Novel biological, structural and functional neuroimaging techniques have allowed a better definition of this relation. Depression and cognitive dysfunction share a common neuropathological platform in cortical and sub-cortical brain areas implicated in emotional and cognitive processing which may be under the control of genetic and environmental factors.
authors.affiliation: Department of Neuroscience and Sense Organs, University of Bari, Bari, Italy. apostolos.papazacharias@uniba.it
authors.forename: Apostolos
authors.initials: A
authors.lastname: Papazacharias
authors.forename: Marcello
authors.initials: M
authors.lastname: Nardini
mesh_terms: D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping; D003071:Cognition / Q000502:physiology; D003072:Cognition Disorders / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology* / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology* / Q000523:psychology; D004644:Emotions / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009434:Neural Pathways / Q000473:pathology / Q000503:physiopathology