title: Efficiency at rest: magnetoencephalographic resting-state connectivity and individual differences in verbal working memory.
abstract: Inter-individual differences in cognitive performance are based on an efficient use of task-related brain resources. However, little is known yet on how these differences might be reflected on resting-state brain networks. Here we used Magnetoencephalography resting-state recordings to assess the relationship between a behavioral measurement of verbal working memory and functional connectivity as measured through Mutual Information. We studied theta (4-8 Hz), low alpha (8-10 Hz), high alpha (10-13 Hz), low beta (13-18 Hz) and high beta (18-30 Hz) frequency bands. A higher verbal working memory capacity was associated with a lower mutual information in the low alpha band, prominently among right-anterior and left-lateral sensors. The results suggest that an efficient brain organization in the domain of verbal working memory might be related to a lower resting-state functional connectivity across large-scale brain networks possibly involving right prefrontal and left perisylvian areas.
authors.affiliation: Laboratory for Cognitive and Computational Neurosciences, Centre for Biomedical Technology (Technical University of Madrid and Complutense University of Madrid), Campus Montegancedo, 28223, Pozuelo de Alarcón, Madrid, Spain. david.delrio@ctb.upm.es
authors.forename: David
authors.initials: D
authors.lastname: del Río
authors.forename: Pablo
authors.initials: P
authors.lastname: Cuesta
authors.forename: Ricardo
authors.initials: R
authors.lastname: Bajo
authors.forename: Javier
authors.initials: J
authors.lastname: García-Pacios
authors.forename: Ramón
authors.initials: R
authors.lastname: López-Higes
authors.forename: Francisco
authors.initials: F
authors.lastname: del-Pozo
authors.forename: Fernando
authors.initials: F
authors.lastname: Maestú
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology; D004526:Efficiency / Q000502:physiology*; D005260:Female; D006801:Humans; D007206:Individuality; D015225:Magnetoencephalography / Q000379:methods*; D008297:Male; D008570:Memory, Short-Term / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology; D010775:Photic Stimulation / Q000379:methods; D012146:Rest / Q000502:physiology*; D014706:Verbal Learning / Q000502:physiology*; D055815:Young Adult