title: Tumor conditioned media from colorectal cancer patients inhibits dendritic cell maturation.
abstract: Tumors inhibit dendritic cell maturation and function in order to evade host immunity. We showed that conditioned media from tumor explant tissue, taken from metastatic colorectal cancer patients, significantly inhibits maturation of dendritic cells.
authors.affiliation: Department of Surgery; Trinity Centre for Health Sciences; Institute of Molecular Medicine; St. James's Hospital; Dublin, Ireland.
authors.forename: Adriana J
authors.initials: AJ
authors.lastname: Michielsen
authors.forename: Jacintha N
authors.initials: JN
authors.lastname: O'Sullivan
authors.forename: Elizabeth J
authors.initials: EJ
authors.lastname: Ryan