title: [Glucocorticoids in rheumatic diseases - what is the optimal dose?].
abstract: Glucocorticoids (GCs) have been an invaluable tool in the treatment of patients with rheumatic diseases. The aims of GC therapy vary for different indications from symptom management to disease-modification and immunmodulation. Even after 60 years of GC use, there is still a lack of knowledge concerning optimal therapeutic strategies with GCs. Taking this into account, optimal dosage schedules for inflammatory rheumatic diseases are discussed.
authors.affiliation: Internistische und rheumatologische Gemeinschaftspraxis, Gladbeck, und Abteilung für Medizinische Informatik, Biometrie und Epidemiologie, Ruhr-Universität Bochum. gundi.krause@t-online.de
authors.forename: D
authors.initials: D
authors.lastname: Krause
mesh_terms: D000367:Age Factors; D004164:Diphosphonates / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D019317:Evidence-Based Medicine; D005598:Fractures, Spontaneous / Q000139:chemically induced / Q000517:prevention & control; D005938:Glucocorticoids / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D010024:Osteoporosis / Q000139:chemically induced / Q000517:prevention & control; D017410:Practice Guidelines as Topic; D020551:Pulse Therapy, Drug; D012216:Rheumatic Diseases / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D004164:Diphosphonates; D005938:Glucocorticoids