title: Exercise in neuromuscular diseases.
abstract: This article reviews the current knowledge regarding the benefits and contraindications of exercise on individuals with neuromuscular diseases (NMDs). Specific exercise prescriptions for individuals with NMDs do not exist because the evidence base is limited. Understanding the effect of exercise on individuals with NMDs requires the implementation of a series of multicenter, randomized controlled trials that are sufficiently powered and use reliable and valid outcome measures to assess the effect of exercise interventions-a major effort for each NMD. In addition to traditional measures of exercise efficacy, outcome variables should include measures of functional status and health-related quality of life.
authors.affiliation: Department of Rehabilitation Medicine, University of California, Davis, 4860 Y Street Suite, 3850, Sacramento, CA 95817, USA. rtabresch@ucdavis.edu
authors.forename: R Ted
authors.initials: RT
authors.lastname: Abresch
authors.forename: Gregory T
authors.initials: GT
authors.lastname: Carter
authors.forename: Jay J
authors.initials: JJ
authors.lastname: Han
authors.forename: Craig M
authors.initials: CM
authors.lastname: McDonald
mesh_terms: D015444:Exercise / Q000502:physiology*; D005081:Exercise Therapy / Q000009:adverse effects; D006801:Humans; D017240:Mitochondrial Myopathies / Q000534:rehabilitation; D016472:Motor Neuron Disease / Q000534:rehabilitation; D009136:Muscular Dystrophies / Q000534:rehabilitation; D009220:Myositis / Q000534:rehabilitation; D009468:Neuromuscular Diseases / Q000534:rehabilitation*; D010523:Peripheral Nervous System Diseases / Q000534:rehabilitation; D016032:Randomized Controlled Trials as Topic; D057185:Sedentary Behavior