title: [Complications of association magnesium sulfate with nicardipine during preeclampsia: report of 2 cases].
abstract: The authors report a heart failure and a collapse following concurrently administration of nicardipine and magnesium sulfate. These two drugs have potential negative inotropic effect and decrease systemic vascular resistance. Magnesium sulfate is the first-line treatment for the prevention of primary and recurrent eclamptic seizures. Combination with calcium channel blockers should be used cautiously.
authors.affiliation: Service de gynécologie-obstétrique, centre hospitalier Franck-Joly, avenue de Gaulle, 97320 Saint-Laurent-du-Maroni, Guyane française. g.carles@ch-ouestguyane.fr
authors.forename: G
authors.initials: G
authors.lastname: Carles
authors.forename: J
authors.initials: J
authors.lastname: Helou
authors.forename: N
authors.initials: N
authors.lastname: Alassas
authors.forename: F
authors.initials: F
authors.lastname: Dallah
authors.forename: N
authors.initials: N
authors.lastname: Ibrahim
mesh_terms: D000293:Adolescent; D000328:Adult; D002121:Calcium Channel Blockers / Q000009:adverse effects; D002585:Cesarean Section; D003864:Depression, Chemical; D004347:Drug Interactions; D004461:Eclampsia / Q000517:prevention & control; D005260:Female; D005865:Gestational Age; D006333:Heart Failure / Q000139:chemically induced*; D006801:Humans; D008278:Magnesium Sulfate / Q000009:adverse effects*; D009200:Myocardial Contraction / Q000187:drug effects; D009529:Nicardipine / Q000009:adverse effects*; D011225:Pre-Eclampsia / Q000188:drug therapy*; D011247:Pregnancy; D014655:Vascular Resistance / Q000187:drug effects
chemical_list: D002121:Calcium Channel Blockers; D008278:Magnesium Sulfate; D009529:Nicardipine