title: Heterogeneous asymmetric Henry-Michael one-pot reaction synergically catalyzed by grafted chiral bases and inherent achiral hydroxyls on mesoporous silica surface.
abstract: Highly efficient and enantioselective asymmetric Henry-Michael one-pot reaction has been achieved on bifunctional heterogeneous catalysts with inherent achiral hydroxyls as acidic sites and immobilized chiral amines as basic sites. Final products were afforded in yields of up to 85% and ee of 99%.
authors.affiliation: State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, PO Box 98, No. 15 BEISANHUAN East Road, Beijing 100029, P. R. China. yangshanshan213@gmail.com
authors.forename: Shanshan
authors.initials: S
authors.lastname: Yang
authors.forename: Jing
authors.initials: J
authors.lastname: He
mesh_terms: D000447:Aldehydes / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000737:chemistry; D002384:Catalysis; D006878:Hydroxides / Q000737:chemistry*; D015394:Molecular Structure; D016062:Porosity; D011759:Pyrrolidines / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D013237:Stereoisomerism; D013499:Surface Properties
chemical_list: D000447:Aldehydes; D000588:Amines; D006878:Hydroxides; D011759:Pyrrolidines; D012822:Silicon Dioxide; C031356:hydroxide ion