title: Cytomegalovirus pneumonia in immunocompetent host: case report and literature review.
abstract: CMV infection is highly prevalent in general population and its clinical picture generally ranges from asymptomatic disease to mononucleosis-like syndrome. While severe life-threatening CMV disease is well documented in certain immunocompromised risk groups, severe infection with symptomatic pneumonia in immunocompetent hosts has been rarely documented. In this paper we describe a case of primary CMV infection, complicated by severe CMV pneumonia in an immunocompetent host, successfully treated with oral valganciclovir. Moreover, we reviewed CMV pneumonia cases in immunocompetent adults reported in the literature.
authors.affiliation: Second Infectious Diseases Division, INMI L.Spallanzani, 00149 Rome, Italy. elisabetta75@gmail.com
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Grilli
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Galati
authors.forename: Licia
authors.initials: L
authors.lastname: Bordi
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Taglietti
authors.forename: Nicola
authors.initials: N
authors.lastname: Petrosillo
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D002648:Child; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology* / Q000821:virology; D015774:Ganciclovir / Q000008:administration & dosage / Q000031:analogs & derivatives; D006801:Humans; D008297:Male; D008875:Middle Aged; D011024:Pneumonia, Viral / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology* / Q000821:virology; D016896:Treatment Outcome; D000077562:Valganciclovir; D055815:Young Adult
chemical_list: D000077562:Valganciclovir; D015774:Ganciclovir