title: [Mycoplasmas and antibodies anti-Chlamydia in semen of infertile men and their relationship with seminal quality and markers of male accessory sex glands].
abstract: Male infertility may be due to inflammation or infection of the genital tract among other causes. Male accessory sex glands and sperm function may also be involved in the problem of infertility. This study tries to associate the most frequent bacteria in semen of infertile men including Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum with the seminal characteristics and levels of fructose, citric acid and alpha-neutral glucosidase as markers of the accessory glands. Detection of antibodies anti Chlamydia trachomatis indicated that it was the most prevalent germ. Antibodies (Ab) anti-Chlamydia, Mycoplasma hominis and Ureaplasma urealyticum were associated with a decrease of the glandular markers fructose and alpha-neutral glucosidase. On the other hand, there were increased pH and leukocytospermia in men positive for antibodies anti-Chlamydia. Microbiological and biochemical evaluation of semen could orient more about the spread of infection and allow for the selection of the most effective therapy. We find that microbiological and glandular accessory markers assessments in semen are important to diagnose and to treat infections.
authors.affiliation: Centro Diagnóstico de Infertilidad y Enfermedades Genéticas (CEDIEG), Facultad de Farmacia y Bioanálisis, Universidad de Los Andes, Mérida, Venezuela. ricardolozanoh@hotmail.com
authors.forename: Ricardo
authors.initials: R
authors.lastname: Lozano-Hernández
authors.forename: Giovanny
authors.initials: G
authors.lastname: Vivas-Acevedo
authors.forename: María Gladys
authors.initials: MG
authors.lastname: Muñoz de Vera
mesh_terms: D000328:Adult; D000906:Antibodies / Q000032:analysis*; D015415:Biomarkers / Q000032:analysis; D002689:Chlamydia / Q000276:immunology*; D005837:Genitalia, Male; D006801:Humans; D007248:Infertility, Male / Q000276:immunology* / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D009174:Mycoplasma / Q000302:isolation & purification*; D012661:Semen / Q000276:immunology* / Q000382:microbiology*; D055101:Semen Analysis; D055815:Young Adult
chemical_list: D000906:Antibodies; D015415:Biomarkers