title: Citalopram- and escitalopram-induced symptomatic hyponatremia.
abstract: We report the cases of 2 patients who developed syndrome of inappropriate antidiuretic hormone secretion (SIADH) after initiating therapy with the selective serotonin reuptake inhibitors, citalopram and escitalopram. Both the patients were women, aged 65 and 81 years old. The first consulted for headache, nausea and vomiting and the second for asthenia and malaise. Both were under treatment for depression with citalopram (20 mg/day) and escitalopram (10 mg/day), respectively. We review the literature on SIADH induced by citalopram and escitalopram and the pathophysiological mechanisms of this syndrome.
authors.affiliation: Servicio de Diabetes, Endocrinología y Nutrición. Hospital Universitario de Girona Dr. Josep Trueta. Girona. España.
authors.forename: Elisabet
authors.initials: E
authors.lastname: Juncà Creus
authors.forename: Mònica
authors.initials: M
authors.lastname: Recasens Sala
authors.forename: Wifredo
authors.initials: W
authors.lastname: Ricart Ángel
authors.forename: José
authors.initials: J
authors.lastname: Manuel Fernández-Real