title: Janus-faced PIDD: a sensor for DNA damage-induced cell death or survival?
abstract: In this issue of Molecular Cell, an activator of the PIDDosome (a complex comprising of PIDD, RAIDD, and caspase-2) is described in experiments detailing endogenous PIDDosome assembly and caspase-2 function after DNA damage in the presence of Chk1 suppression (Ando et al., 2012).
authors.affiliation: Department of Biochemistry, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.
authors.forename: Francis
authors.initials: F
authors.lastname: McCoy
authors.forename: Laura
authors.initials: L
authors.lastname: Eckard
authors.forename: Leta K
authors.initials: LK
authors.lastname: Nutt