title: Sepsis update: management of severe sepsis and septic shock in the emergency department after the withdrawal of Xigris.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Green
authors.forename: Dennis
authors.initials: D
authors.lastname: Djogovic
authors.forename: Daniel
authors.initials: D
authors.lastname: Howes
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy; D004636:Emergency Service, Hospital / Q000458:organization & administration*; D005343:Fibrinolytic Agents; D006801:Humans; D011486:Protein C / Q000627:therapeutic use*; D019984:Quality Indicators, Health Care; D011994:Recombinant Proteins / Q000627:therapeutic use; D056737:Safety-Based Drug Withdrawals; D012772:Shock, Septic / Q000188:drug therapy*; D028761:Withholding Treatment
chemical_list: D000890:Anti-Infective Agents; D005343:Fibrinolytic Agents; D011486:Protein C; D011994:Recombinant Proteins; C421124:drotrecogin alfa activated