title: Giant extracranial aneurysm of the internal carotid artery in neurofibromatosis type 1. A case report and review of the literature.
abstract: Neurofibromatosis type 1 (NF-1) is an autosomal dominant disorder characterized by cutaneous pigmentations, neurofibromas, Lisch nodules and neuroectodermal tumors. Supra-aortic vessel aneurysms may affect patients with NF-1 and can be associated with rupture, ischemic complications and compression symptoms. We describe a 48-year-old woman with NF-1 and an extracranial 3×5 cm right internal carotid artery aneurysm. After balloon test occlusion the patient was treated with parent artery sacrifice which led to significant shrinkage on follow-up MR and reduction of compression symptoms. The literature concerning internal carotid artery aneurysms associated with NF-1 is reviewed evaluating the possible therapeutic options.
authors.affiliation: Department of Neuroradiology, S. Agostino-Estense Hospital, Modena Local Health Trust, Modena, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Moratti
authors.forename: T
authors.initials: T
authors.lastname: Andersson
mesh_terms: D000783:Aneurysm / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D021721:Balloon Occlusion; D002340:Carotid Artery Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D002343:Carotid Artery, Internal / Q000473:pathology*; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000150:complications*