title: [Severe sick sinus syndrome associated with a Werner's syndrome].
abstract: A 39-year-old woman was explored for recurrent syncopes. She was already known for a Werner's syndrome with symptoms of aging disorders. The explorations revealed an episode of sinusal arrest. A pacemaker was implanted. This case emphasises the relation between Werner syndrome and the development of cardiovascular abnormalities. This pathology should be recalled in young patients with symptoms of aging disorders and cardiovascular abnormalities. Valvular abnormalities, myocardial infarction and stroke are the major complications of Werner's syndrome. This case indicates that a sick sinus syndrome is a rare but possible complication of Werner's syndrome.
authors.affiliation: Unité de rythmologie, groupe hospitalier intercommunal Le Raincy-Montfermeil, 10, rue du Général-Leclerc, 93370 Montfermeil, France. walamara@yahoo.fr
authors.forename: W
authors.initials: W
authors.lastname: Amara
authors.forename: D
authors.initials: D
authors.lastname: Poindron
authors.forename: H
authors.initials: H
authors.lastname: Salih
authors.forename: C
authors.initials: C
authors.lastname: Moini
mesh_terms: D000328:Adult; D002304:Cardiac Pacing, Artificial / Q000379:methods; D005260:Female; D006801:Humans; D010138:Pacemaker, Artificial; D012804:Sick Sinus Syndrome / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D016896:Treatment Outcome; D014898:Werner Syndrome / Q000150:complications*