title: Necrotizing pneumonia in the community.
abstract: A 62-year-old man presented with general fatigue. He was diagnosed with septic shock and severe pneumonia. The sputum at admission yielded methicillin-sensitive Staphylococcus aureus (MSSA) strain and methicillin-resistant S. aureus (MRSA) strain. Despite antibiotic treatment, he did not improve. A chest computed tomography (CT) revealed multilobar cavity lesions. Only MRSA strain was confirmed at that time. We diagnosed him with necrotizing pneumonia. Despite treatment with vancomycin, his pneumonia worsened and he died. At autopsy, many gram-positive cocci were observed in the lungs. The clinical presentation of our patient was different from typical CA-MRSA-mediated necrotizing pneumonia.
authors.affiliation: Department of Respiratory Medicine, Nishi-Kobe Medical Center, Japan. h.otera@onh.go.jp
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Otera
authors.forename: Go
authors.initials: G
authors.lastname: Yamamoto
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Ohkusu
authors.forename: Haruka
authors.initials: H
authors.lastname: Kozuki
authors.forename: Kimio
authors.initials: K
authors.lastname: Hashimoto
authors.forename: Kimihide
authors.initials: K
authors.lastname: Tada
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus; D008875:Middle Aged; D009336:Necrosis; D011023:Pneumonia, Staphylococcal / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology*; D013203:Staphylococcal Infections / Q000150:complications* / Q000188:drug therapy; D017211:Treatment Failure; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin