title: Direct analysis of cannabis samples by desorption atmospheric pressure photoionization-mass spectrometry.
abstract: Fast analysis of cannabis samples without prior sample preparation or chromatography was performed using desorption atmospheric pressure photoionization-mass spectrometry (DAPPI-MS). The MS(2) spectra of the molecular ions of tetrahydrocannabinol (THC) and cannabidiol (CBD) formed in DAPPI-MS showed distinct product ions, unlike the protonated molecules formed with other ambient mass spectrometry techniques, making possible the reliable identification of THC from cannabis samples.
authors.affiliation: Division of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Helsinki, Finland. tiina.kauppila@helsinki.fi
authors.forename: Tiina J
authors.initials: TJ
authors.lastname: Kauppila
authors.forename: Anu
authors.initials: A
authors.lastname: Flink
authors.forename: Ulla-Maija
authors.initials: UM
authors.lastname: Laakkonen
authors.forename: Laura
authors.initials: L
authors.lastname: Aalberg
authors.forename: Raimo A
authors.initials: RA
authors.lastname: Ketola
mesh_terms: D001274:Atmospheric Pressure; D002185:Cannabidiol / Q000032:analysis*; D002188:Cannabis / Q000737:chemistry*; D013759:Dronabinol / Q000032:analysis*; D013287:Illicit Drugs / Q000032:analysis; D013058:Mass Spectrometry / Q000379:methods*
chemical_list: D013287:Illicit Drugs; D002185:Cannabidiol; D013759:Dronabinol