title: Papillary lesions of the breast diagnosed using core needle biopsies.
abstract: Papillary lesions of the breast include a broad spectrum of lesions, from benign papillomas to papillary carcinomas. It is difficult to determine whether a lesion is benign or malignant based on the fragmented material of a core needle biopsy (CNB). This study evaluated patients with papillary lesions examined using CNB. We retrospectively reviewed 31 papillary lesions diagnosed using CNB between 2004 and 2007. The clinical findings of benign and malignant papillary lesions were compared. The average patient age was 48.9 years. Twelve patients presented with a discharge and 10 patients presented with a lump. Eight patients were asymptomatic. The initial diagnoses by CNB of the 31 lesions were 25 intraductal papillomas, 4 intracystic papillomas and 2 adenomas. After CNB, excisional biopsies were performed in 23 patients and biopsies with a Mammotome(®) in 2 patients. Seven patients underwent regular follow-up. Five (16%) of the 31 patients with papillary lesions were ultimately diagnosed with breast cancer. The average distance from the nipple to a tumor diagnosed as malignant was 2.46 cm, which was longer than for a tumor diagnosed as benign. Ultimately, 5 papillary lesions (16%) were diagnosed as breast cancer. To avoid overlooking a malignancy, surgical excision is advantageous for papillary lesions, particularly those located far from the nipple.
authors.affiliation: Departments of Thoracic and Visceral Organ Surgery, and.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Tokiniwa
authors.forename: Jun
authors.initials: J
authors.lastname: Horiguchi
authors.forename: Daisuke
authors.initials: D
authors.lastname: Takata
authors.forename: Mami
authors.initials: M
authors.lastname: Kikuchi
authors.forename: Nana
authors.initials: N
authors.lastname: Rokutanda
authors.forename: Rin
authors.initials: R
authors.lastname: Nagaoka
authors.forename: Ayako
authors.initials: A
authors.lastname: Sato
authors.forename: Hiroki
authors.initials: H
authors.lastname: Odawara
authors.forename: Katsunori
authors.initials: K
authors.lastname: Tozuka
authors.forename: Tetsunari
authors.initials: T
authors.lastname: Oyama
authors.forename: Izumi
authors.initials: I
authors.lastname: Takeyoshi