title: Primary malignant esophageal melanoma arising from localized benign melanocytosis.
abstract: A heavy drinker and smoker had a normal UGI-endoscopy in 1996. In 1999, a repeat examination disclosed distal esophageal benign melanocytosis, typical, macro- and microscopically. Endoscopic and microscopic features were stable in 2002 and 2004. In 2007, dysphagia prompted an endoscopy, which disclosed a poorly differentiated epidermoid carcinoma at 19 cm and black nodules of the cardia with a microscopy typical of malignant melanoma, uT3N1 at EUS. Radiochemotherapy led to an 8-month improvement, which did not prevent death one year after diagnosis.
authors.affiliation: Cabinet d'anatomopathologie, 182, rue de Périgueux, 16000 Angoulême, France. bmaroy@yahoo.fr
authors.forename: Bernard
authors.initials: B
authors.lastname: Maroy
authors.forename: Francois
authors.initials: F
authors.lastname: Baylac
mesh_terms: D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects; D002471:Cell Transformation, Neoplastic; D059248:Chemoradiotherapy; D003680:Deglutition Disorders / Q000209:etiology; D004935:Esophageal Diseases / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000473:pathology* / Q000628:therapy; D008548:Melanosis / Q000473:pathology*; D012907:Smoking / Q000009:adverse effects