title: Migraine and genetic polymorphisms: an overview.
abstract: The relationship between genetic polymorphisms and migraine as a cause of an increased risk of thrombotic disorders development is still debated In this respect, factor V Leiden, factor V (H1299R), prothrombin G20210A, factor XIII (V34L), β-fibrinogen, MTHFR (C677T), MTHFR (A1298C), APO E, PAI-1, HPA-1 and ACE I/D seem to play a determinant role in vascular diseases related to migraine. The present review analyzes both the incidence of the above genetic vascular mutations in migraineurs and the most re-cent developments related to genetic polymorphisms and migraine.
authors.affiliation: Neurophysiopathology Service, S. Luca Hospital, Vallo della Lucania (SA), Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Pizza
authors.forename: Anella
authors.initials: A
authors.lastname: Agresta
authors.forename: Antonio
authors.initials: A
authors.lastname: Agresta
authors.forename: Eros
authors.initials: E
authors.lastname: Lamaida
authors.forename: Norman
authors.initials: N
authors.lastname: Lamaida
authors.forename: Francesco
authors.initials: F
authors.lastname: Infante
authors.forename: Anna
authors.initials: A
authors.lastname: Capasso