title: The future of human health risk assessment of environmental chemicals.
abstract: Dramatic changes are beginning to take place in risk assessment, changes that will involve rapid, high-throughput assays capable of analyzing large numbers of samples in a short time. These new systems will incorporate many of the aspects of cellular and molecular biology, including human and human-derived cell lines, toxicogenomics, proteomics, and metabolomics. The large amount of data generated will require a systems biology approach if it is to be reduced to generalizations of value in risk management. The current chapter briefly describes the emerging systems and their component parts.
authors.affiliation: Department of Environmental and Molecular Toxicology, North Carolina State University, Raleigh, North Carolina, USA.
authors.forename: Ernest
authors.initials: E
authors.lastname: Hodgson
mesh_terms: D000818:Animals; D054750:Ecotoxicology; D015386:Hazardous Substances / Q000633:toxicity*; D006801:Humans; D011634:Public Health; D018570:Risk Assessment; D012308:Risk Management; D018675:Toxicity Tests
chemical_list: D015386:Hazardous Substances