title: Successful treatment of fulminant community-acquired Pseudomonas aeruginosa necrotizing pneumonia in a previously healthy young man.
abstract: This report presents a case of fulminant community-acquired Pseudomonas aeruginosa necrotizing pneumonia in a previously healthy young man, including an analysis of the virulence of the P.aeruginosa isolated from the patient. The patient was successfully treated with intensive care and antibiotic treatment. This study analyzed the pathogenicity of the isolated strain both in vivo (using a mouse pneumonia model) and in vitro (using biofilm production), but could not explain how an otherwise healthy young man developed such severe community-acquired P.aeruginosa pneumonia. Although rare in community-acquired pneumonia, P.aeruginosa infection should be considered in patients with severe rapidly progressive pneumonia.
authors.affiliation: Department of Respiratory Medicine, Kurashiki Central Hospital, Japan. keikunimasa@gmail.com
authors.forename: Kei
authors.initials: K
authors.lastname: Kunimasa
authors.forename: Tadashi
authors.initials: T
authors.lastname: Ishida
authors.forename: Soichiro
authors.initials: S
authors.lastname: Kimura
authors.forename: Maki
authors.initials: M
authors.lastname: Tanaka
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Kouyama
authors.forename: Shigeki
authors.initials: S
authors.lastname: Yamashita
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Morita
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Tachibana
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Tokioka
authors.forename: Akihiro
authors.initials: A
authors.lastname: Ito
authors.forename: Chisato
authors.initials: C
authors.lastname: Sumi
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Tateda
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017714:Community-Acquired Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D008297:Male; D009336:Necrosis; D018410:Pneumonia, Bacterial / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D011552:Pseudomonas Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D011550:Pseudomonas aeruginosa; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents