title: Should we individualize breast cancer screening?
abstract: Publicly organized population breast cancer screening is presently hotly debated. Indeed, population screening is poorly effective, induces harms in a healthy population and is costly. However, stopping all kind of screening of low- and average-risk women would be problematic as about 70% of breast cancers are diagnosed in those subgroups, and maintaining current population screening in high-risk women would be insufficient. We propose herein a review about the advantages and the inconvenience of individualized screening. The latter could be a more efficient strategy. The principles of individualized screening are (a) to start from the age at which the breast cancer risk is equal to that for an average women aged 50 years, (b) to stop when the risk of co-mortality exceeds the risk of breast cancer mortality, (c) to adapt the exams frequency and the imaging modalities to the individual risk and to the breast density, (d) to reassess regularly and individually the screening strategy, and (e) to discuss honestly with each woman in order to help her to decide if she participates or not.
authors.affiliation: Department of Senology, CHU of Liège, avenue de l'hôpital B35, Liège, Belgium. joelle.desreux@chu.ulg.ac.be
authors.forename: J
authors.initials: J
authors.lastname: Desreux
authors.forename: V
authors.initials: V
authors.lastname: Bleret
authors.forename: E
authors.initials: E
authors.lastname: Lifrange
mesh_terms: D000367:Age Factors; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000401:mortality; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D012306:Risk