title: Real-time monitoring biomarker expression of carcinoma cells by surface plasmon resonance biosensors.
abstract: A novel surface plasmon resonance (SPR) biosensor which is capable of monitoring proteomic biomarker secretion from living cells is reported here. Vascular endothelial growth factor (VEGF) secretion from living SKOV-3 ovarian cancer cells was measured for concept demonstration.
authors.affiliation: Nanobioengineering/Nanobioelectronics Laboratory, Department of Biomedical Engineering, Florida International University, 10555 W Flagler Street, Miami, FL 33174, USA.
authors.forename: Chang
authors.initials: C
authors.lastname: Liu
authors.forename: Tingjun
authors.initials: T
authors.lastname: Lei
authors.forename: Kosuke
authors.initials: K
authors.lastname: Ino
authors.forename: Tomokazu
authors.initials: T
authors.lastname: Matsue
authors.forename: Nongjian
authors.initials: N
authors.lastname: Tao
authors.forename: Chen-Zhong
authors.initials: CZ
authors.lastname: Li
mesh_terms: D015415:Biomarkers / Q000032:analysis / Q000378:metabolism; D002277:Carcinoma / Q000737:chemistry* / Q000378:metabolism / Q000473:pathology; D045744:Cell Line, Tumor; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000737:chemistry* / Q000378:metabolism / Q000473:pathology; D020349:Surface Plasmon Resonance; D042461:Vascular Endothelial Growth Factor A / Q000032:analysis* / Q000378:metabolism
chemical_list: D015415:Biomarkers; D042461:Vascular Endothelial Growth Factor A