title: Allergic contact dermatitis from dimethyl fumarate after contact with a Chinese sofa.
abstract: BACKGROUND
  Dimethyl fumarate has been successfully used in the treatment of psoriasis in the past. Despite its clinical use, cutaneous contact with this molecule may cause contact dermatitis.
  
  
  OBJECTIVE
  We report a case in which skin exposure to a synthetic fabric sofa containing dimethyl fumarate made by a Chinese furniture manufacturer resulted in a severe, pruritic, papulovesicular, eczematous dermatitis to the sites of contact with the sofa.
  
  
  METHODS
  The patient was patch-tested with serial dilutions of dimethyl fumarate.
  
  
  RESULTS
  Patch testing results revealed strong positive reactions to dimethyl fumarate at different concentrations.
  
  
  CONCLUSIONS
  Dimethyl fumarate is a potent contact sensitizer and is commonly found in sachets inside furniture and footwear boxes.
authors.affiliation: University of Ottawa, Ottawa, ON, Canada. joseph.doumit@gmail.com
authors.forename: Joseph
authors.initials: J
authors.lastname: Doumit
authors.forename: Geneviève
authors.initials: G
authors.lastname: Gavigan
authors.forename: Melanie
authors.initials: M
authors.lastname: Pratt
mesh_terms: D000328:Adult; D002681:China; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D000069462:Dimethyl Fumarate; D005500:Follow-Up Studies; D005650:Fumarates / Q000009:adverse effects*; D006801:Humans; D007374:Interior Design and Furnishings; D008297:Male; D010328:Patch Tests; D012867:Skin / Q000187:drug effects / Q000473:pathology*
chemical_list: D005650:Fumarates; D000069462:Dimethyl Fumarate