title: A canine model of proximal descending thoracic aortic aneurysm created with an autologous pericardial patch.
abstract: OBJECTIVE
  To establish an animal model of proximal descending thoracic aortic aneurysm for the study of branched stent grafts.
  
  
  METHODS
  Eleven mongrel dogs underwent the surgical procedure during which an autologous pericardial patch was sewn onto a longitudinal incision in the anterolateral wall of the thoracic aorta near the left subclavian artery to create an artificial thoracic aortic aneurysm.
  
  
  RESULTS
  All eleven animals survived the surgical procedure. One animal died from rupture at the surgical site during the first week after surgery. The distance between the artificial aneurysm and the left subclavian artery was 8.29 ± 0.91 mm. The average diameter of the artificial aneurysms did not significantly change over the 4-month follow-up period.
  
  
  CONCLUSIONS
  A canine model for proximal descending thoracic aortic aneurysm can be achieved using a safe and convenient method. The model can be used in the study of new branched stent graft applied to the aortic arch.
authors.affiliation: Department of Interventional Radiology, the First Affiliated Hospital of China Medical University, Shenyang, Liaoning, China.
authors.forename: Weixiao
authors.initials: W
authors.lastname: Li
authors.forename: Ke
authors.initials: K
authors.lastname: Xu
authors.forename: Yicheng
authors.initials: Y
authors.lastname: Ni
authors.forename: Hongshan
authors.initials: H
authors.lastname: Zhong
authors.forename: Yonghua
authors.initials: Y
authors.lastname: Bi
mesh_terms: D000818:Animals; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging / Q000601:surgery*; D017545:Aortic Aneurysm, Thoracic / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D001019:Aortic Rupture / Q000209:etiology; D001027:Aortography / Q000379:methods; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation; D004195:Disease Models, Animal; D004285:Dogs; D057510:Endovascular Procedures / Q000295:instrumentation; D010496:Pericardium / Q000637:transplantation*; D011474:Prosthesis Design; D015607:Stents; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D014182:Transplantation, Autologous