title: Human health risk of dietary intake of organochlorine pesticide residues in bovine meat and tissues from Veracruz, México.
abstract: Tissue distribution patterns of organochlorine pesticides in bovine carcasses varied significantly among seasons, geographic locations and tissues. The highest concentrations of Σ-DDT during the dry season were detected in lungs from Paso de Ovejas (2,834.90μg/kg lipid) and, during the rainy season, Lindane and Σ-HCH in muscle and lung samples from Paso de Ovejas (995.80 and 1,690.10μg/kg lipid). Estimated daily intakes of γ-HCH and Σ-DDT (3.35 and 1.22μg/kg bw/day) through consumption of muscle tissues from Paso de Ovejas and Puente Nacional during the rainy season showed the highest contribution. During the rainy season the highest non-cancer Hazard Ratios estimated corresponded to γ-HCH (3.97) and Σ-DDT (4.39) detected in muscle samples from Puente Nacional. The highest Hazard Ratios of cancer risk to the 95th centile daily consumption through meat corresponded to p,p'-DDT from Alvarado (7.76E+06) and from Paso de Ovejas for γ-HCH (1.50E+05) during rainy season. The results indicate potential non- and carcinogenic risks to consumer health through meat consumption.
authors.affiliation: Faculty of Veterinary Medicine, Universidad Veracruzana, Veracruz, Mexico. vpardio@uv.mx
authors.forename: Violeta
authors.initials: V
authors.lastname: Pardío
authors.forename: David
authors.initials: D
authors.lastname: Martínez
authors.forename: Argel
authors.initials: A
authors.lastname: Flores
authors.forename: Dora
authors.initials: D
authors.lastname: Romero
authors.forename: Víctor
authors.initials: V
authors.lastname: Suárez
authors.forename: Karla
authors.initials: K
authors.lastname: López
authors.forename: Roxana
authors.initials: R
authors.lastname: Uscanga
mesh_terms: D000825:Animal Structures / Q000737:chemistry*; D000818:Animals; D002417:Cattle; D004781:Environmental Exposure / Q000009:adverse effects; D005506:Food Contamination / Q000032:analysis*; D006262:Health; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis* / Q000633:toxicity; D008460:Meat / Q000032:analysis*; D008800:Mexico; D009132:Muscles / Q000737:chemistry; D010573:Pesticide Residues / Q000032:analysis* / Q000633:toxicity; D012307:Risk Factors
chemical_list: D006843:Hydrocarbons, Chlorinated; D010573:Pesticide Residues