title: A regio- and diastereoselective palladium-catalyzed cyclopropanation of norbornene derivatives with molecular oxygen as the sole oxidant.
abstract: A mild and efficient Pd-catalyzed cyclopropanation of norbornene derivatives with tertiary propargylic alcohols using molecular oxygen as the sole oxidant is described. This process allows quick and atom-economical assembly of various 1,2,3-trisubstituted cyclopropanes bearing α,β-unsaturated ketone moieties in high yields as a single regio- and diastereoisomer.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
authors.forename: Yang
authors.initials: Y
authors.lastname: Gao
authors.forename: Huawen
authors.initials: H
authors.lastname: Huang
authors.forename: Wei
authors.initials: W
authors.lastname: Zeng
authors.forename: Derong
authors.initials: D
authors.lastname: Cao
mesh_terms: D002384:Catalysis; D003521:Cyclopropanes / Q000737:chemistry*; D015394:Molecular Structure; D009636:Norbornanes / Q000138:chemical synthesis* / Q000737:chemistry; D009942:Organometallic Compounds / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D003521:Cyclopropanes; D009636:Norbornanes; D009942:Organometallic Compounds; D016877:Oxidants; D010165:Palladium; D010100:Oxygen