title: Optical properties of hematoporphyrin monomethyl ether (HMME), a PDT photosensitizer.
abstract: We report on some of the optical properties of Hemoporfin (hematoporphyrin monomethyl ether, HMME), a photodynamic therapy (PDT) photosensitizer that has been in clinical trials in China since the early 1990s. We characterized the photosensitizer on the basis of one- and two-photon absorption and fluorescence emission. The effects of photobleaching were probed to characterize its decay kinetics. Additionally, we determined time resolved fluorescence and thermal effects on fluorescence and absorption properties.
authors.affiliation: Department of Electrical Engineering, Colorado Advanced Photonics Technology (CAPT) Laboratory, University of Colorado Denver, CO, USA.
authors.forename: Tim C
authors.initials: TC
authors.lastname: Lei
authors.forename: Gregory F
authors.initials: GF
authors.lastname: Glazner
authors.forename: Michael
authors.initials: M
authors.lastname: Duffy
authors.forename: Larry
authors.initials: L
authors.lastname: Scherrer
authors.forename: Srinivas
authors.initials: S
authors.lastname: Pendyala
authors.forename: Buhong
authors.initials: B
authors.lastname: Li
authors.forename: Xiuli
authors.initials: X
authors.lastname: Wang
authors.forename: Hongwei
authors.initials: H
authors.lastname: Wang
authors.forename: Zheng
authors.initials: Z
authors.lastname: Huang
mesh_terms: D005453:Fluorescence; D006415:Hematoporphyrins / Q000737:chemistry* / Q000528:radiation effects*; D008027:Light; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000737:chemistry* / Q000528:radiation effects*; D011829:Radiation Dosage; D013696:Temperature
chemical_list: D006415:Hematoporphyrins; D017319:Photosensitizing Agents; C494379:hematoporphyrin monomethyl ether