title: Site-specific pathology in breast reduction mammoplasty.
abstract: OBJECTIVE
  To investigate the feasibility and clinical value of site-specific pathology in breast reduction mammoplasty.
  
  
  METHODS
  Totally 127 patients who underwent breast reduction mammoplasty from June 2007 to June 2010 were included. Pathologic specimens were sent for frozen pathology according to the clock-wise method. Patients with confirmed cancer were arranged for conservative breast surgery.
  
  
  RESULTS
  Of the 127 patients, 53 patients (41.7%) had gland hyperplasia; 7 had fibroadenoma (5.5%); 1 (0.79%) had ductal carcinoma in situ, who underwent breast conserving surgery, following by chemotherapy and radiotherapy, no relapse was noted during the three-year follow-up.
  
  
  CONCLUSIONS
  Clock-wise method is useful to locate the tumor and ensure the patients to receive skin-spared breast resection even cancer is detected.
authors.affiliation: Department of Plastic and Reconstructive Surgery, PUMC Hospital, CAMS and PUMC, Beijing, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Long
authors.forename: Xiao-jun
authors.initials: XJ
authors.lastname: Wang
authors.forename: Yang
authors.initials: Y
authors.lastname: Wang
authors.forename: Ming
authors.initials: M
authors.lastname: Bai
authors.forename: Ke-xin
authors.initials: KX
authors.lastname: Song
authors.forename: Ru
authors.initials: R
authors.lastname: Zhao
mesh_terms: D000293:Adolescent; D000328:Adult; D001940:Breast / Q000473:pathology* / Q000601:surgery; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D016462:Mammaplasty; D015412:Mastectomy, Segmental; D008875:Middle Aged; D055815:Young Adult