title: [Usefullness of the Kramer's index in the diagnosis of hyperbilirubinemia of the newborn].
abstract: The objective of the present study was to correlate seric values of bilirubin with the Kramer's index in a group of newborns with neonatal jaundice, from three different ethnic groups. This was a prospective, randomized, observational, descriptive-analytical, longitudinal, comparative and controlled study of 50 newborns with neonatal jaundice, without complications. They were divided into three groups: A (Control), n = 25, of Caucasian descent; B, n = 15, of local indigenous descent (Wayúu) and C, n = 10, of Afro-American descent. Each newborn was screened at the start of the study for their Kramer's dermic areas and simultaneously, a venous blood sample from the arm was taken for bilirubin quantification. They were compared through a correlation-regression analysis. Values at the beginning of the study were: serum bilirubin 12.02 +/- 3.41 mg/dL, and 62.8% of neonates were at Kramer's level 3. There were no differences among the ethnic groups studied and the correlation bilirubin/Kramer's index was r= 0.93 (p < 0.005). At the third day, both bilirubin and Kramer's indexes started to decrease. There were no ethnic differences. In conclusion, the Kramer's method offers multiple advantages to evaluate a jaundiced newborn; it is a safe, non-invasive method with no cost. Besides, it is of great help in the prevention of the kernicterus. It is recommended to implement the use of the Kramer method in all the newborns units in our Hospitals, preferably in those lacking transcutaneous bilirubinometers.
authors.affiliation: Departamento de Pediatría, Hospital Materno-Infantil "Dr. Raúl Leoni", Escuela de Medicina, Facultad de Medicina, Universidad del Zulia, Maracaibo, Venezuela. miaparada@hotmail.com
authors.forename: Sara M
authors.initials: SM
authors.lastname: Acosta-Torres
authors.forename: Marco T
authors.initials: MT
authors.lastname: Torres-Espina
authors.forename: José A
authors.initials: JA
authors.lastname: Colina-Araujo
authors.forename: José A
authors.initials: JA
authors.lastname: Colina-Chourio
mesh_terms: D006801:Humans; D006932:Hyperbilirubinemia / Q000175:diagnosis*; D007231:Infant, Newborn; D007565:Jaundice / Q000175:diagnosis; D015997:Neonatal Screening / Q000379:methods*; D011446:Prospective Studies