title: Aminoindanol-based chiral derivatizing agents for the determination of the absolute configuration of carboxylic acids.
abstract: New chiral derivatizing agents have been prepared through a simple, short-step synthesis. The absolute configuration of α-chiral carboxylic acids can be assigned on the basis of the NMR chemical shift difference between diastereomeric esters. Because of the modular structures of the agents, the anisotropic effect could be easily manipulated to afford large chemical shift differences even in polar solvents.
authors.affiliation: Department of Chemistry and Research Institute for Natural Sciences, Korea University, Seoul 136-701, Republic of Korea.
authors.forename: Minjung
authors.initials: M
authors.lastname: Park
authors.forename: Seon-mi
authors.initials: SM
authors.lastname: Kim
authors.forename: Kihang
authors.initials: K
authors.lastname: Choi
mesh_terms: D002264:Carboxylic Acids / Q000032:analysis*; D007189:Indans / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000592:standards; D015394:Molecular Structure; D012015:Reference Standards; D013237:Stereoisomerism
chemical_list: D002264:Carboxylic Acids; D007189:Indans; C116915:aminoindanol