title: The dawn of angiogenesis modeling: regenerating vasculature from human pluripotent stem cells.
abstract: Efficient generation of functional human vascular endothelial cells and smooth muscle cells from pluripotent stem cells is an extensively studied topic and of great interest in the stem cell field. Though thought to be technically complex and difficult, substantial progress has been made towards this direction. Here we aim to summarize and discuss the most recent advances in this topic and their future perspective in research and clinic.
authors.affiliation: Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
authors.forename: Fei
authors.initials: F
authors.lastname: Yi
authors.forename: Jing
authors.initials: J
authors.lastname: Qu
authors.forename: Guang-Hui
authors.initials: GH
authors.lastname: Liu
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Izpisua Belmonte
mesh_terms: D002454:Cell Differentiation; D042783:Endothelial Cells / Q000166:cytology; D006801:Humans; D008954:Models, Biological; D032389:Myocytes, Smooth Muscle / Q000166:cytology; D018919:Neovascularization, Physiologic / Q000502:physiology*; D039904:Pluripotent Stem Cells / Q000166:cytology* / Q000378:metabolism; D055293:Receptors, Urokinase Plasminogen Activator / Q000378:metabolism; D012038:Regeneration
chemical_list: D055293:Receptors, Urokinase Plasminogen Activator