title: [Recurrence of hydatid cyst of liver: predictive factors: Tunisian experience].
abstract: Cystic echinococcosis is a public health problem. Surgery represents the basic treatment and the surgeon is regularly faced with the choice of the appropriate surgical procedure (radical versus conservative surgical approach). The conservative procedure is safe and easy but can lead to a recurrence in the site of residual cavity. The aim of this study was to evaluate the predictive factors of the recurrence of hepatic hydatid cysts, to optimize surgical management and to implement preventive measures. The current retrospective study included 391 patients with hepatic hydatid cysts operated at our institution from 1996 to 2006. The diagnosis of recurrence was suspected by radiological survey and confirmed at laparotomy. The univariate study of predictive factors of recurrence was based on the Fisher test and the multivariate one on the logistic regression model. The recurrence rate reached 12% in our study with an average period of 50 months. Univariate analysis showed that the predictive factors of recurrence were: the rural origin of patients, the voluminous cysts larger than 7 cm, and unilocular hydatid cyst. Multivariate analysis showed that only voluminous cysts and unilocular ones were the predictive factors of recurrence. The unilocular and voluminous hydatid cysts represent the cysts that relapse frequently because of their immunogenic character and the presence of exocysts in the pericysts. This is very important for the therapeutic strategy the main aim of which is to prevent the recurrence.
authors.affiliation: Service de chirurgie, hôpital La Rabta, faculté de médecine de Tunis, Tunis, Tunisie. h_bdioui@yahoo.fr
authors.forename: H
authors.initials: H
authors.lastname: Bedioui
authors.forename: H
authors.initials: H
authors.lastname: Ayari
authors.forename: K
authors.initials: K
authors.lastname: Bouslama
authors.forename: H
authors.initials: H
authors.lastname: Maghrebi
authors.forename: H
authors.initials: H
authors.lastname: Hsairi
authors.forename: M
authors.initials: M
authors.lastname: Jouini
authors.forename: J-M
authors.initials: JM
authors.lastname: Kacem
authors.forename: Z Ben
authors.initials: ZB
authors.lastname: Safta
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002648:Child; D004444:Echinococcosis, Hepatic / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000276:immunology / Q000601:surgery; D005260:Female; D006801:Humans; D007813:Laparotomy / Q000379:methods; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D012424:Rural Population / Q000706:statistics & numerical data; D014057:Tomography, X-Ray Computed; D014416:Tunisia / Q000453:epidemiology; D014463:Ultrasonography; D055815:Young Adult