title: Effect of composite yogurt enriched with acacia fiber and Bifidobacterium lactis.
abstract: OBJECTIVE
  To investigate whether composite yogurt with acacia dietary fiber and Bifidobacterium lactis (B. lactis) has additive effects in irritable bowel syndrome (IBS).
  
  
  METHODS
  A total of 130 patients were randomly allocated to consume, twice daily for 8 wk, either the composite yogurt or the control product. The composite yogurt contained acacia dietary fiber and high-dose B. lactis together with two classic yogurt starter cultures. Patients were evaluated using the visual analog scale via a structured questionnaire administered at baseline and after treatment.
  
  
  RESULTS
  Improvements in bowel habit satisfaction and overall IBS symptoms from baseline were significantly higher in the test group than in the control group (27.16 vs 15.51, P = 0.010, 64.2 ± 17.0 vs 50.4 ± 20.5, P < 0.001; respectively). In constipation-predominant IBS, improvement in overall IBS symptoms was significantly higher in the test group than in the control group (72.4 ± 18.4 vs 50.0 ± 21.8, P < 0.001). In patients with diarrhea-predominant IBS, improvement in bowel habit satisfaction from baseline was significantly higher in the test group than in the control group (32.90 vs 7.81, P = 0.006).
  
  
  CONCLUSIONS
  Our data suggest that composite yogurt enriched with acacia fiber and B. lactis has greater therapeutic effects in patients with IBS than standard yogurt.
authors.affiliation: Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135-710, South Korea.
authors.forename: Yang Won
authors.initials: YW
authors.lastname: Min
authors.forename: Sang Un
authors.initials: SU
authors.lastname: Park
authors.forename: Yeon Sil
authors.initials: YS
authors.lastname: Jang
authors.forename: Young-Ho
authors.initials: YH
authors.lastname: Kim
authors.forename: Poong-Lyul
authors.initials: PL
authors.lastname: Rhee
authors.forename: Seo Hyun
authors.initials: SH
authors.lastname: Ko
authors.forename: Nami
authors.initials: N
authors.lastname: Joo
authors.forename: Sun Im
authors.initials: SI
authors.lastname: Kim
authors.forename: Cheol-Hyun
authors.initials: CH
authors.lastname: Kim
authors.forename: Dong Kyung
authors.initials: DK
authors.lastname: Chang
mesh_terms: D000045:Acacia; D000328:Adult; D001644:Bifidobacterium; D003248:Constipation / Q000453:epidemiology; D003967:Diarrhea / Q000453:epidemiology; D004043:Dietary Fiber / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000150:complications / Q000178:diet therapy*; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D015995:Prevalence; D019936:Probiotics / Q000627:therapeutic use*; D016896:Treatment Outcome; D015014:Yogurt