title: Novel polyomaviruses in South American bats and their relationship to other members of the family Polyomaviridae.
abstract: Bats are the natural reservoir of a variety of viruses, including a polyomavirus (PyV) from a North American brown bat. We investigated 163 spleen samples from 22 bat species from French Guiana for the presence of PyVs. In total, we detected 25 PyV-positive animals belonging to nine different bat species. Phylogenetic analysis was performed on the genomes of eight representative PyVs, and showed that the bat PyVs form three distinct lineages within the genus Orthopolyomavirus and are genetically different from the previously described North American bat virus. Interestingly, two lineages cluster with PyVs found in chimpanzees, orangutans and gorillas. In addition, one group of bat PyVs is genetically related to the human Merkel cell polyomavirus.
authors.affiliation: Department of Virology, Biomedical Primate Research Centre (BPRC), Lange Kleiweg 161, 2288GJ Rijswijk, The Netherlands.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Fagrouch
authors.affiliation: Department of Virology, Biomedical Primate Research Centre (BPRC), Lange Kleiweg 161, 2288GJ Rijswijk, The Netherlands.
authors.forename: Roya
authors.initials: R
authors.lastname: Sarwari
authors.affiliation: Laboratoire des Interactions Virus-Hôtes, Institut Pasteur de la Guyane, 23 avenue Pasteur, BP6010, 97306 Cayenne Cedex, French Guiana.
authors.forename: Anne
authors.initials: A
authors.lastname: Lavergne
authors.affiliation: ONF Guyane, Service développement Sylvétude, Réserve Montabo, BP7002, 97307 Cayenne Cedex, French Guiana.
authors.forename: Marguerite
authors.initials: M
authors.lastname: Delaval
authors.affiliation: Laboratoire des Interactions Virus-Hôtes, Institut Pasteur de la Guyane, 23 avenue Pasteur, BP6010, 97306 Cayenne Cedex, French Guiana.
authors.forename: Benoît
authors.initials: B
authors.lastname: de Thoisy
authors.affiliation: Laboratoire des Interactions Virus-Hôtes, Institut Pasteur de la Guyane, 23 avenue Pasteur, BP6010, 97306 Cayenne Cedex, French Guiana.
authors.forename: Vincent
authors.initials: V
authors.lastname: Lacoste
authors.affiliation: Department of Virology, Biomedical Primate Research Centre (BPRC), Lange Kleiweg 161, 2288GJ Rijswijk, The Netherlands.
authors.forename: Ernst J
authors.initials: EJ
authors.lastname: Verschoor
mesh_terms: D000818:Animals; D002685:Chiroptera / Q000821:virology*; D004197:Disease Reservoirs / Q000662:veterinary / Q000821:virology; D005616:French Guiana; D016679:Genome, Viral; D006071:Gorilla gorilla / Q000821:virology; D006801:Humans; D059965:Merkel cell polyomavirus / Q000145:classification / Q000235:genetics; D008969:Molecular Sequence Data; D002679:Pan troglodytes / Q000821:virology; D010802:Phylogeny; D027382:Polyomaviridae / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D011120:Polyomavirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D057079:Pongo / Q000821:virology; D013020:South America; D013045:Species Specificity