title: Serum and urine boron and selenium levels in children with resistant epilepsy.
abstract: OBJECTIVE
  To determine the role of serum and urine selenium, and boron levels in children with resistant epilepsy.
  
  
  METHODS
  Serum and urine boron and selenium levels were studied in 53 cases (32 boys and 21 girls) diagnosed with resistant epilepsy between April 2006 and February 2007 at the Department of Pediatric Neurology, Erciyes University, Kayseri, Turkey.  Differences between groups were assessed using Student's t-test. Countable data were defined as percentage. Inter-group difference was assessed by Chi-square test. P-values less than 0.05 were considered significant.
  
  
  RESULTS
  When serum and urine boron and selenium levels were evaluated and compare with controls, a statistically significant difference was found in serum selenium, urine selenium, and urine boron levels (p<0.05). No significant difference was found in serum boron levels (p>0.05).
  
  
  CONCLUSIONS
  It was observed that there is a need for selenium supplementation in treatment of patients with resistant epilepsy, while no etiologic role is observed for boron.
authors.affiliation: Department of Pediatric Neurology, Erciyes University Medical Faculty, Kayseri, Turkey. huseyinper@yahoo.com
authors.forename: Huseyin
authors.initials: H
authors.lastname: Per
authors.forename: Mehmet
authors.initials: M
authors.lastname: Canpolat
authors.forename: Ugur
authors.initials: U
authors.lastname: Sahin
authors.forename: Hakan
authors.initials: H
authors.lastname: Gumus
authors.forename: Bahadir
authors.initials: B
authors.lastname: Konuskan
authors.forename: Sefer
authors.initials: S
authors.lastname: Kumandas
mesh_terms: D000293:Adolescent; D001895:Boron / Q000097:blood / Q000378:metabolism* / Q000652:urine; D002648:Child; D004827:Epilepsy / Q000097:blood / Q000378:metabolism* / Q000652:urine; D005260:Female; D006801:Humans; D008297:Male; D012643:Selenium / Q000097:blood / Q000378:metabolism* / Q000652:urine
chemical_list: D012643:Selenium; D001895:Boron