title: Graphene oxide as a matrix for the immobilization of glucose oxidase.
abstract: The adsorption of glucose oxidase (GOD) on graphene oxide (GO) nanoparticles without using any cross-linking reagents and/or additional surface modification was studied. Results of Fourier-transform infrared and ultraviolet-visible absorption spectroscopy confirmed that GOD was successfully immobilized on GO surface. The obtained immobilized GOD showed a wide range of pH stability and improved thermal and storage stability. In addition, GO exhibited good biocompatibility, which has potential advantages for biomedical and clinical diagnosis applications.
authors.affiliation: School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300130, China.
authors.forename: Liya
authors.initials: L
authors.lastname: Zhou
authors.forename: Yanjun
authors.initials: Y
authors.lastname: Jiang
authors.forename: Jing
authors.initials: J
authors.lastname: Gao
authors.forename: Xinqiang
authors.initials: X
authors.lastname: Zhao
authors.forename: Li
authors.initials: L
authors.lastname: Ma
mesh_terms: D001234:Aspergillus niger / Q000201:enzymology*; D004795:Enzyme Stability; D004800:Enzymes, Immobilized / Q000737:chemistry; D005656:Fungal Proteins / Q000737:chemistry*; D005949:Glucose Oxidase / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D007700:Kinetics; D053758:Nanoparticles / Q000737:chemistry; D010087:Oxides / Q000737:chemistry*
chemical_list: D004800:Enzymes, Immobilized; D005656:Fungal Proteins; D010087:Oxides; D006108:Graphite; D005949:Glucose Oxidase