title: Does ovarian endometrioma affect the number of oocytes retrieved for in vitro fertilization?
abstract: OBJECTIVE
  To investigate the effects of ovarian endometrioma on the number of oocytes retrieved for in vitro fertilization (IVF).
  
  
  BACKGROUND
  The presence of endometrioma may be the most important predictor of a poor reproductive outcome. Literature data suggest that ovarian endometriomas might affect the response to ovarian stimulation and oocyte retrieval.
  
  
  METHODS
  The present retrospective study evaluates 2,023 women who applied to our center with an infertility complaint. Twenty-nine women with endometriomas (group 1) who were treated with IVF were included in the study. They were compared with 51 women with unexplained infertility (group 2) regarding the number of retrieved oocytes after egg retrieval and number of metaphase II oocytes. The diagnosis of endometrioma was made via ultrasound examination with the identification of low-density cystic masses in the ovaries. The patients underwent a controlled ovarian hyperstimulation (COH) with either the long agonist mini-dose protocol or the multi-dose antagonist protocol.
  
  
  RESULTS
  The incidence of endometrioma in infertile women was found to be 1.4 %. The women's ages ranged between 24 and 45 years, and the duration of their infertility ranged between 12 and 216 months. The endometrioma was bilateral in 24 % of the cases. The mean endometrioma diameter was 26.2±7.3 mm for the right ovary and 23.2±6.1 mm for the left ovary. The average number of retrieved oocytes after egg retrieval in groups 1 and 2 was 12.4±8.3 and 12.2±8.6, respectively. The average number of metaphase II oocytes in groups 1 and 2 was 8.6±6.1 and 9.4±7.3, respectively. The number of retrieved oocytes after egg retrieval and the number of metaphase II oocytes in both endometrioma group and unexplained infertile group were similar (p >0.05).
  
  
  CONCLUSIONS
  Endometrioma did not reduce the number of retrieved oocytes in a COH cycle for IVF treatment. However it should be noted that the ovarian response is affected by the size of endometriomas, bilaterality, previous surgeries, recurrence, and the patient's age (Tab. 1, Ref. 31).
authors.affiliation: Department of Obstetrics and Gynecology, Kahramanmaras Sutcuimam University, Kahramanmaras, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Kiran
authors.forename: D C
authors.initials: DC
authors.lastname: Arikan
authors.forename: M
authors.initials: M
authors.lastname: Kaplanoglu
authors.forename: U
authors.initials: U
authors.lastname: Bisak
authors.forename: M T
authors.initials: MT
authors.lastname: Cetin
mesh_terms: D000328:Adult; D004715:Endometriosis / Q000150:complications*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000150:complications / Q000628:therapy*; D054315:Oocyte Retrieval; D010049:Ovarian Diseases / Q000150:complications*; D055815:Young Adult