title: Maternal physical activity and insulin action in pregnancy and their relationships with infant body composition.
abstract: OBJECTIVE
  We sought to assess the association between maternal gestational physical activity and insulin action and body composition in early infancy.
  
  
  METHODS
  At 28-32 weeks' gestation, pregnant women participating in an observational study in Sweden underwent assessments of height, weight, and body composition, an oral glucose tolerance test, and 10 days of objective physical activity assessment. Thirty mothers and infants returned at 11-19 weeks postpartum. Infants underwent assessments of weight, length, and body composition.
  
  
  RESULTS
  Early insulin response was correlated with total physical activity (r = -0.47; P = 0.007). Early insulin response (r = -0.36; P = 0.045) and total physical activity (r = 0.52; P = 0.037) were also correlated with infant fat-free mass. No maternal variable was significantly correlated with infant adiposity.
  
  
  CONCLUSIONS
  The relationships between maternal physical activity, insulin response, and infant fat-free mass suggest that physical activity during pregnancy may affect metabolic outcomes in the mother and her offspring.
authors.affiliation: Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Skåne University Hospital, Lund University, Malmö, Sweden.
authors.forename: Jeremy
authors.initials: J
authors.lastname: Pomeroy
authors.forename: Frida
authors.initials: F
authors.lastname: Renström
authors.forename: Anna M
authors.initials: AM
authors.lastname: Gradmark
authors.forename: Ingrid
authors.initials: I
authors.lastname: Mogren
authors.forename: Margareta
authors.initials: M
authors.lastname: Persson
authors.forename: Les
authors.initials: L
authors.lastname: Bluck
authors.forename: Antony
authors.initials: A
authors.lastname: Wright
authors.forename: Steven E
authors.initials: SE
authors.lastname: Kahn
authors.forename: Magnus
authors.initials: M
authors.lastname: Domellöf
authors.forename: Paul W
authors.initials: PW
authors.lastname: Franks
mesh_terms: D000328:Adult; D001823:Body Composition / Q000502:physiology*; D001827:Body Height / Q000502:physiology; D001835:Body Weight / Q000502:physiology; D005260:Female; D005865:Gestational Age; D005951:Glucose Tolerance Test; D006801:Humans; D007223:Infant; D007328:Insulin / Q000378:metabolism*; D009043:Motor Activity / Q000502:physiology*; D011247:Pregnancy; D011795:Surveys and Questionnaires
chemical_list: D007328:Insulin