title: Lewis acid-catalyzed Friedel-Crafts alkylations of 3-hydroxy-2-oxindole: an efficient approach to the core structure of azonazine.
abstract: A Lewis acid catalyzed Friedel-Crafts reaction of electron rich aromatics with 3-alkyl-3-hydroxy-2-oxindole (5) has been developed. The methodology provides a straightforward access to the core of azonazine (2) sharing an all-carbon quaternary stereocenter at the tetracyclic ring junction.
authors.affiliation: Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, MP 460 023, India.
authors.forename: Santanu
authors.initials: S
authors.lastname: Ghosh
authors.forename: Lakshmana K
authors.initials: LK
authors.lastname: Kinthada
authors.forename: Subhajit
authors.initials: S
authors.lastname: Bhunia
authors.forename: Alakesh
authors.initials: A
authors.lastname: Bisai