title: Adipocytokine levels in children: effects of fatness and training.
abstract: To investigate the effects of obesity and exercise training on plasma adipocytokines a sample of 42 children (lean = 24, %BF = 17.8 ± 7.5%; obese = 18; %BF = 29.1 ± 9.3%; mean age = 12.4 ± 1.9 yrs), were divided into 4 age-matched for activity groups: lean inactive (n = 11), obese inactive (n = 9), lean active (n = 13) and obese active (n = 9). Active children participated in swimming training (≥1 year, ≥3 times/week, ≥1 h per session, covering a distance of 10,000-12,000 m per week).Obese individuals demonstrated greater visfatin levels (3.3 ± 1.3 ng/ml) than their lean counterparts (2.6 ± 1.1 ng/ml; p = .06) whereas adiponectin was significantly lower in obese children (3.8 ± 1.9) than their lean counterparts (5.9 ± 2.7; p £ .05). Insulin and HOMA values were significantly greater in obese compared with lean children (p £ .05). Within obese individuals, active individuals had significantly lower visfatin levels (2.8 ± 1.2 ng/ml) compared with their inactive counterparts (3.8 ± 1.2 ng/ml; p £ .05). Resistin levels were comparable between groups (p > .05). Childhood obesity elevates visfatin and lowers adiponectin levels whereas exercise training could reduce visfatin levels in obese children.
authors.affiliation: Dept. of Physical Education and Sport Science, University of Thessaly, Karies, Trikala, Greece.
authors.forename: Sofia
authors.initials: S
authors.lastname: Aggeloussi
authors.forename: Anastasios A
authors.initials: AA
authors.lastname: Theodorou
authors.forename: Vassilis
authors.initials: V
authors.lastname: Paschalis
authors.forename: Michalis G
authors.initials: MG
authors.lastname: Nikolaidis
authors.forename: Ioannis G
authors.initials: IG
authors.lastname: Fatouros
authors.forename: Emmanuel O
authors.initials: EO
authors.lastname: Owolabi
authors.forename: Dimitris
authors.initials: D
authors.lastname: Kouretas
authors.forename: Yiannis
authors.initials: Y
authors.lastname: Koutedakis
authors.forename: Athanasios Z
authors.initials: AZ
authors.lastname: Jamurtas
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D002648:Child; D016207:Cytokines / Q000097:blood*; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D054409:Nicotinamide Phosphoribosyltransferase / Q000097:blood*; D009765:Obesity / Q000097:blood* / Q000523:psychology; D052243:Resistin / Q000097:blood*; D011795:Surveys and Questionnaires; D013550:Swimming / Q000502:physiology
chemical_list: D052242:Adiponectin; D015415:Biomarkers; D016207:Cytokines; D052243:Resistin; D054409:Nicotinamide Phosphoribosyltransferase; C085455:nicotinamide phosphoribosyltransferase, human