title: Cell adhesion: a FERM grasp of the tail sorts out integrins.
abstract: As well as modulating integrin activation, a conserved NPxY motif in integrin cytoplasmic tails that binds the FERM-domain-containing proteins kindlin and sorting nexin 17 plays pivotal roles in integrin recycling and degradation.
authors.affiliation: Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06520-8066, USA.
authors.forename: Nina N
authors.initials: NN
authors.lastname: Brahme
authors.forename: David A
authors.initials: DA
authors.lastname: Calderwood
mesh_terms: D000818:Animals; D003598:Cytoskeletal Proteins / Q000502:physiology*; D039081:Integrin alpha5beta1 / Q000502:physiology*; D009124:Muscle Proteins / Q000502:physiology*; D016608:Talin / Q000502:physiology*
chemical_list: D003598:Cytoskeletal Proteins; D039081:Integrin alpha5beta1; D009124:Muscle Proteins; D016608:Talin; C527802:kindlin-2 protein, mouse; C496077:Tln1 protein, mouse