title: A synergistically enhanced T(1) -T(2) dual-modal contrast agent.
abstract: Monodisperse Gd(2) O(3) -embedded iron oxide (GdIO) nanoparticles can simultaneously enhance the local magnetic field intensities of each other under an external magnetic field and result in synergistic enhancement of T(1)  and T(2)  effects. GdIO nanoparticles have the unique property to be both T(1)  and T(2)  contrast agents and can potentially lead to higher accuracy in cancer diagnosis, particularly liver tumors.
authors.affiliation: State Key Laboratory of Physical Chemistry of Solid Surfaces, The Key Laboratory for Chemical Biology of Fujian Province and Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China.
authors.forename: Zijian
authors.initials: Z
authors.lastname: Zhou
authors.forename: Dengtong
authors.initials: D
authors.lastname: Huang
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Bao
authors.forename: Qiaoli
authors.initials: Q
authors.lastname: Chen
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
authors.forename: Zhong
authors.initials: Z
authors.lastname: Chen
authors.forename: Xiaoyuan
authors.initials: X
authors.lastname: Chen
authors.forename: Jinhao
authors.initials: J
authors.lastname: Gao
mesh_terms: D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D003287:Contrast Media / Q000737:chemistry* / Q000633:toxicity; D005290:Ferric Compounds / Q000737:chemistry; D005682:Gadolinium / Q000737:chemistry; D006367:HeLa Cells; D056945:Hep G2 Cells; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008280:Magnetics; D053768:Metal Nanoparticles / Q000737:chemistry / Q000633:toxicity; D051379:Mice; D011859:Radiography
chemical_list: D003287:Contrast Media; D005290:Ferric Compounds; C000499:ferric oxide; C030581:gadolinium oxide; D005682:Gadolinium