title: Synthetic chloride transporters with the binding mode observed in a ClC chloride channel.
abstract: A series of synthetic molecules bearing the same hydrogen bonding mode observed in StClC were prepared and their transport ability of chloride ion across a lipid membrane was systematically optimized.
authors.affiliation: Department of Chemistry, Yonsei University, Seoul 120-749, Korea.
authors.forename: Ye Rin
authors.initials: YR
authors.lastname: Choi
authors.forename: Min Kyung
authors.initials: MK
authors.lastname: Chae
authors.forename: Dongwook
authors.initials: D
authors.lastname: Kim
authors.forename: Myoung Soo
authors.initials: MS
authors.lastname: Lah
authors.forename: Kyu-Sung
authors.initials: KS
authors.lastname: Jeong
mesh_terms: D001665:Binding Sites; D018118:Chloride Channels / Q000737:chemistry / Q000378:metabolism*; D002712:Chlorides / Q000737:chemistry / Q000378:metabolism*; D006860:Hydrogen Bonding; D007477:Ions / Q000737:chemistry / Q000378:metabolism; D008051:Lipid Bilayers / Q000737:chemistry / Q000378:metabolism; D000644:Quaternary Ammonium Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000378:metabolism; D012486:Salmonella typhimurium / Q000378:metabolism
chemical_list: C086321:CLC-1 channel; D018118:Chloride Channels; D002712:Chlorides; D007477:Ions; D008051:Lipid Bilayers; D000644:Quaternary Ammonium Compounds; C009405:tetrabutylammonium