title: [Incidence of thromboembolic events after major operations in patients with haemophilia].
abstract: Thromboembolic complications may occur in patients with major operations even after routine thromboprophylaxis with low-molecular-weight-heparin. In this retrospective, single center survey the post-operative course of patients with haemophilia was investigated.
  
  
  METHODS
  Overall, the postoperative course in 85 patients with haemophilia A and B (median age: 43 years, 18-73 years) and 139 surgical procedures was analyzed. The surgical procedures mainly consist of major orthopedic surgery (58 total knee replacement, 15 hip replacement, 17 other major orthopedic surgery, 15 minor orthopedic procedures). Additional surgical procedures were abdominal-surgical (18), urological (8), neurosurgical (5).
  
  
  RESULTS
  During the post-operative observation period a small number of wound healing complications occurred (4%). None of the patients developed symptomatic deep vein thrombosis or lung embolism.
  
  
  CONCLUSIONS
  There seems to a decreased risk of postoperative thromboembolism in patients with haemophilia.
authors.affiliation: Hämophiliezentrum, Medizinische Klinik III, Institut für Transfusionsmedizin, Goethe Universität, Frankfurt am Main.
authors.forename: S
authors.initials: S
authors.lastname: Krekeler
authors.forename: S
authors.initials: S
authors.lastname: Alesci
authors.forename: W
authors.initials: W
authors.lastname: Miesbach
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D005260:Female; D006467:Hemophilia A / Q000453:epidemiology* / Q000601:surgery*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D018570:Risk Assessment; D012307:Risk Factors; D013923:Thromboembolism / Q000453:epidemiology*; D055815:Young Adult