title: Wet-chemical green synthesis of L-lysine amino acid stabilized biocompatible iron-oxide magnetic nanoparticles.
abstract: In this paper, we report a novel method for the synthesis of L-Lysine (lys) amino acid coated maghemite (gamma-Fe2O3) magnetic nanoparticles (MNPs). The facile and cost effective method permitted preparation of the high-quality superparamagnetic gamma-Fe2O3 MNPs with hydrophilic and biocompatible nature. For this work, first we synthesized magnetite phase Fe3O4/lys by wet chemical method and oxidized to y-Fe2O3 in controlled oxidizing environment, as evidenced by XRD and VSM magnetometry. The crystallite size and magnetization of gamma-Fe2O3/lys MNPs was found to be 14.5 nm, 40.6 emu/gm respectively. The surface functionalization by L-lysine amino acid and metal-ligand bonding was also confirmed by FTIR spectroscopy. The hydrodynamic diameter, colloidal stability and surface charge on MNPs were characterized by DLS and zeta potential analyser.
authors.affiliation: Department of Metallurgical Engineering and Materials Science, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.
authors.forename: Rahul
authors.initials: R
authors.lastname: Krishna
authors.forename: Elby
authors.initials: E
authors.lastname: Titus
authors.forename: Rohit
authors.initials: R
authors.lastname: Krishna
authors.forename: Neelkanth
authors.initials: N
authors.lastname: Bardhan
authors.forename: Dhirendra
authors.initials: D
authors.lastname: Bahadur
authors.forename: José
authors.initials: J
authors.lastname: Gracio
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis* / Q000737:chemistry; D001672:Biocompatible Materials; D005290:Ferric Compounds / Q000737:chemistry*; D008239:Lysine / Q000737:chemistry*; D008280:Magnetics; D053768:Metal Nanoparticles; D018625:Microscopy, Atomic Force; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D000596:Amino Acids; D001672:Biocompatible Materials; D005290:Ferric Compounds; C000499:ferric oxide; D008239:Lysine