title: Two-year results of translating the diabetes prevention program into an urban, underserved community.
abstract: The purpose of the study was to examine the long-term effect of a Group Lifestyle Balance (GLB) program on weight, impaired fasting glucose, hypertension, and hyperlipidemia in an urban, medically underserved community.
  
  
  
  This study was a single-arm prospective intervention study that was designed to test the effectiveness of a community-based GLB intervention. In sum, 638 residents from 11 targeted neighborhoods were screened for body mass index ≥ 25 kg/m(2) and metabolic syndrome. Eligible individuals took part in a 12-week GLB intervention (n = 105) that addressed weight loss and physical activity. Subjects were followed for 24 months.
  
  
  
  The probability of being at risk for diabetes and cardiovascular disease was significantly reduced by 25.7% over the long-term follow-up. Of the participants who lost at least 5% of their body weight following the intervention, 52.6% maintained the 5% weight loss at their last follow-up time, weighing about 20 lb less than they did at baseline.
  
  
  
  Risk reduction and weight loss maintenance are possible following a GLB intervention and have substantial potential for future public health impact.
authors.affiliation: The Department of Medical Education, University of Michigan, Ann Arbor, Michigan (Dr Piatt)
authors.forename: Gretchen A
authors.initials: GA
authors.lastname: Piatt
authors.affiliation: The School of Sustainability and the Environment, Chatham University, Pittsburgh, Pennsylvania (Ms Seidel)
authors.forename: Miriam C
authors.initials: MC
authors.lastname: Seidel
authors.affiliation: The Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania (Ms Chen, Dr Zgibor)
authors.forename: Hsiang-Yu
authors.initials: HY
authors.lastname: Chen
authors.affiliation: The University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (Mr Powell)
authors.forename: Robert O
authors.initials: RO
authors.lastname: Powell
authors.affiliation: The Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania (Ms Chen, Dr Zgibor)
authors.forename: Janice C
authors.initials: JC
authors.lastname: Zgibor
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000453:epidemiology / Q000517:prevention & control*; D004038:Diet, Reducing; D015444:Exercise; D005260:Female; D015438:Health Behavior; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000453:epidemiology*; D006973:Hypertension / Q000097:blood / Q000453:epidemiology*; D008297:Male; D008403:Mass Screening; D008507:Medically Underserved Area; D008875:Middle Aged; D010349:Patient Compliance; D010358:Patient Participation; D011236:Prediabetic State / Q000097:blood / Q000453:epidemiology*; D015397:Program Evaluation; D011446:Prospective Studies; D012307:Risk Factors; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology; D014505:Urban Population; D015431:Weight Loss
chemical_list: D001786:Blood Glucose