title: Primary cutaneous aggressive epidermotropic CD4/CD8 double-negative cytotoxic T-cell lymphoma.
abstract: The classification of cutaneous T-cell lymphomas (CTCL) is based on clinical, histological and immunohistochemical findings. Diagnosis may be difficult given the significant heterogeneity of these tumours. We describe herein an original case of primary cutaneous aggressive epidermotropic CD4/CD8 double-negative cytotoxic T-cell lymphoma that illustrates the difficulty in classification.
authors.affiliation: Department of dermatology, Fattouma Bourguiba Hospital, Monastir, Tunisia. akkari.hayet@gmail.com
authors.forename: H
authors.initials: H
authors.lastname: Akkari
authors.forename: H
authors.initials: H
authors.lastname: Belhadjali
authors.forename: A
authors.initials: A
authors.lastname: Moussa
authors.forename: M
authors.initials: M
authors.lastname: Youssef
authors.forename: J
authors.initials: J
authors.lastname: Zili
mesh_terms: D000368:Aged; D015496:CD4-Positive T-Lymphocytes / Q000473:pathology; D018414:CD8-Positive T-Lymphocytes / Q000473:pathology; D004817:Epidermis / Q000276:immunology / Q000473:pathology*; D005260:Female; D006801:Humans; D016399:Lymphoma, T-Cell / Q000276:immunology / Q000473:pathology*; D012878:Skin Neoplasms / Q000276:immunology / Q000473:pathology*; D013602:T-Lymphocytes, Cytotoxic / Q000473:pathology*