title: Using ligand-mapping simulations to design a ligand selectively targeting a cryptic surface pocket of polo-like kinase 1.
authors.affiliation: Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW UK.
authors.forename: Yaw Sing
authors.initials: YS
authors.lastname: Tan
authors.forename: Paweł
authors.initials: P
authors.lastname: Śledź
authors.forename: Steffen
authors.initials: S
authors.lastname: Lang
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Stubbs
authors.forename: David R
authors.initials: DR
authors.lastname: Spring
authors.forename: Chris
authors.initials: C
authors.lastname: Abell
authors.forename: Robert B
authors.initials: RB
authors.lastname: Best
mesh_terms: D001665:Binding Sites; D018797:Cell Cycle Proteins / Q000737:chemistry*; D003198:Computer Simulation; D018360:Crystallography, X-Ray; D016503:Drug Delivery Systems; D057927:Hydrophobic and Hydrophilic Interactions; D008024:Ligands; D008958:Models, Molecular; D010748:Phosphopeptides / Q000737:chemistry; D017346:Protein Serine-Threonine Kinases / Q000737:chemistry*; D011518:Proto-Oncogene Proteins / Q000737:chemistry*; D000097869:Polo-Like Kinase 1
chemical_list: D018797:Cell Cycle Proteins; D008024:Ligands; D010748:Phosphopeptides; D017346:Protein Serine-Threonine Kinases; D011518:Proto-Oncogene Proteins; D000097869:Polo-Like Kinase 1