title: A novel composite porous coating approach for bioactive titanium-based orthopedic implants.
abstract: Surface modification of titanium-based implants is considered a highly effective solution to enhance osseointegration. This study describes a novel Ti/hydroxyapatite (HA) composite porous coating produced using a cold spraying technique. Experimental results indicate desirable open-cell structure with 50-150 μm pore size and 60-65% macroporosity. In particular, the reinforced HA particles are exposed to the surface of the coating resulting in enhanced mineralization ability in simulated body fluid. None of the coatings displayed a cytotoxic response in SaOS-2 cells cultured in vitro for up to 48 h. The bond strength between the porous coating and the Ti substrate was found to be 20 MPa. These properties are comparative to or better than products currently on the market and thus this novel coating has potential use in orthopedics.
authors.affiliation: School of Mechanical and Mining Engineering, University of Queensland, St. Lucia, Queensland, Australia.
authors.forename: Dong
authors.initials: D
authors.lastname: Qiu
authors.forename: Mingxing
authors.initials: M
authors.lastname: Zhang
authors.forename: Lisbeth
authors.initials: L
authors.lastname: Grøndahl
mesh_terms: D002460:Cell Line; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry*; D006801:Humans; D008422:Materials Testing; D019736:Prostheses and Implants; D014025:Titanium / Q000737:chemistry*
chemical_list: D020099:Coated Materials, Biocompatible; D017886:Durapatite; D014025:Titanium