title: [One-stage reconstruction of facial defects after tumor resection with the Integra system].
abstract: BACKGROUND
  In 2010 excellent aesthetic results after basal cell carcinoma excision and one-stage coverage with Integra without split thickness skin graft (STSG) were published in a series of 10 Asian patients. Our aim in this study was to verify these results in a series of Caucasian patients and evaluate this procedure as a possible new standard.
  
  
  METHODS
  6 patients with facial basal cell carcinoma were treated by regular excision with 3 mm safety margins and one-stage coverage with Integra without STSG, followed by a clinical evaluation and fotodocumentation.
  
  
  RESULTS
  In 3 patients local infection occurred with a complete loss of the Integra. 2 out of these 3 patients showed an unaesthetic scar and are considering another surgical approach for correction. The other 3 patients had an uneventful course, unfortunately 2 out of these patients (67%) developed an unaesthetic scar as well and are also considering surgical correction.
  
  
  CONCLUSIONS
  Because of aesthetically unsatisfactory results and high infection rates we abandoned this procedure after 6 patients only. Our standard remains excision with 3 mm safety margins, histological analysis and one-stage repair with local facial flaps.
authors.affiliation: Abteilung Hand- und Plastische Chirurgie, Kantonnspital Luzern, Schweiz. ebodmer@gmx.net
authors.forename: E
authors.initials: E
authors.lastname: Bodmer
authors.forename: R
authors.initials: R
authors.lastname: Osinga
authors.forename: E
authors.initials: E
authors.lastname: Fritsche
authors.forename: U
authors.initials: U
authors.lastname: Hug
mesh_terms: D000328:Adult; D000368:Aged; D002280:Basal Cell Carcinoma / Q000601:surgery*; D002809:Chondroitin Sulfates; D002921:Cicatrix / Q000209:etiology; D003094:Collagen; D005153:Facial Neoplasms / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008866:Microsurgery / Q000379:methods*; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D019651:Plastic Surgery Procedures / Q000379:methods*; D012878:Skin Neoplasms / Q000601:surgery*; D016038:Skin Transplantation; D013530:Surgical Wound Infection / Q000209:etiology
chemical_list: C114835:integra artificial skin; D002809:Chondroitin Sulfates; D003094:Collagen