title: Resilient amorphous networks prepared by photo-crosslinking high-molecular-weight D,L-lactide and trimethylene carbonate macromers: mechanical properties and shape-memory behavior.
abstract: Tough networks are prepared by photo-crosslinking high-molecular-weight DLLA and TMC macromers. These amorphous networks exhibit tunable thermal and mechanical properties and have excellent shape-memory features. Variation of the monomer ratio allows adjustment of T(g) between approximately -13 and +51 °C. The elastic moduli at room temperature can be varied between 4.5 and 2730 MPa. The crosslinks allow the networks to return to their original shape after deformation. 60:40 DLLA:TMC networks have T(g) values between room temperature and body temperature, with mechanical properties at body temperature close to soft tissues. Several medical devices are prepared from these networks.
authors.affiliation: Department of Biomedical Engineering, University Medical Centre Groningen, University of Groningen, P.O. Box 196, 9700 AD Groningen, The Netherlands.
authors.forename: Shahriar
authors.initials: S
authors.lastname: Sharifi
authors.forename: Dirk W
authors.initials: DW
authors.lastname: Grijpma
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000494:pharmacology; D001673:Biodegradation, Environmental; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D004146:Dioxanes / Q000737:chemistry*; D004548:Elasticity; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects; D008027:Light; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008970:Molecular Weight; D055668:Photochemical Processes; D011091:Polyesters / Q000138:chemical synthesis* / Q000494:pharmacology; D013696:Temperature; D013718:Tensile Strength; D023822:Tissue Engineering
chemical_list: D001672:Biocompatible Materials; D004146:Dioxanes; D011091:Polyesters; C121059:poly(lactide-co-trimethylene carbonate); C443643:trimethylene carbonate; C091880:dilactide