title: Design and performance of a desktop time-of-flight mass spectrometer for analyzing metal ions.
abstract: We have described a home-made desktop orthogonal-injection time-of-flight (O-ToF) mass spectrometer combining a collisional cooling system. This O-ToF consists of a simple electrospray ion source, an atmosphere-vacuum interface, an area of transmission, including a radio-frequency only quadrupole (RF- only quadrupole, RFQ) as a collisional cooling cell and an orthogonal ToF mass analyzer. In order to detect ions of small m/z value, such as small metal ions, the RFQ has been improved to weaken the mass discrimination effect against low mass ions. Metal salt solutions were used in the experiment. The system has shown a satisfactory resolving power in the spectra (m/Δm = 3500), a good mass stability, a limit of detection of 80 fg and a mass accuracy of 48 ppm. The dynamic range is found to be from 10(-8) mol L(-1) to 10(-5) mol L(-1), allowing the semi-quantitative analysis of metal ions.
authors.affiliation: School of Chemistry and Environment, South China Normal University, Guangzhou 510006, China.
authors.forename: Changjuan
authors.initials: C
authors.lastname: Guo
authors.forename: Wei
authors.initials: W
authors.lastname: Gao
authors.forename: Zhengzu
authors.initials: Z
authors.lastname: Huang
authors.forename: Hui
authors.initials: H
authors.lastname: Zhu
authors.forename: Zhong
authors.initials: Z
authors.lastname: Fu
authors.forename: Junguo
authors.initials: J
authors.lastname: Dong
authors.forename: Ping
authors.initials: P
authors.lastname: Cheng
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhou
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D007477:Ions; D008670:Metals / Q000032:analysis* / Q000737:chemistry*; D013048:Specimen Handling / Q000295:instrumentation*; D021241:Spectrometry, Mass, Electrospray Ionization / Q000295:instrumentation*
chemical_list: D007477:Ions; D008670:Metals