title: Economic evaluation of the use of exogenous pulmonary surfactants in preterm newborns in a Mexican population.
abstract: OBJECTIVE
  To estimate the cost-effectiveness ratio of surfactant rescue treatment of premature infants with respiratory distress syndrome (RDS) who are covered by the Medical Insurance for a New Generation.
  
  
  METHODS
  A cost-effectiveness evaluation was conducted from the third-payer perspective. Comparisons were made between the use of bovine surfactant (BS) therapy and without BS therapy. A decision tree model with a lifetime horizon was used where the measurements of effectiveness were life years gained (LYG) and quality-adjusted life years (QALYs). A 5% discount rate was considered for costs and health outcomes. All costs are expressed in Mexican pesos 2009.
  
  
  RESULTS
  Incremental cost-effectiveness ratios (ICER) were MXN$136,670 per LYG and MXN$125,250 per QALY.
  
  
  CONCLUSIONS
  Surfactant therapy was confirmed as a cost-effective strategy in accordance with World Health Organization criteria of three per capita gross domestic product (GDP) per QALY in premature infants with RDS in Mexico.
authors.affiliation: Centro de Estudios Económicos y Sociales en Salud, Hospital Infantil de México Federico Gómez, México, DF, México.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Salinas-Escudero
authors.forename: Alfonso
authors.initials: A
authors.lastname: Reyes-López
authors.forename: Juan
authors.initials: J
authors.lastname: Garduño-Espinosa
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: Villasís-Keever
authors.forename: Silvia
authors.initials: S
authors.lastname: Martínez-Valverde
authors.forename: Onofre
authors.initials: O
authors.lastname: Muñoz-Hernández
mesh_terms: D003362:Cost-Benefit Analysis; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008800:Mexico; D011663:Pulmonary Surfactants / Q000191:economics* / Q000627:therapeutic use*; D012127:Respiratory Distress Syndrome, Newborn / Q000188:drug therapy*
chemical_list: D011663:Pulmonary Surfactants