title: Genotoxicity and development effects of brominated flame retardant PBDEs and UV-exposed PBDEs on grass shrimp (Palaemonetes pugio) embryo.
abstract: To understand how polybrominated diphenyl ethers (PBDEs) affect the hatching sensitivity of grass shrimp embryos in different developmental stages, the hatching rates of embryos were measured after PBDE exposure on the early- and late-stage embryo of grass shrimp. PBDEs had no clear influence on the hatching rate. Also, to investigate on the reproductive and genetic toxicities of UV-exposed PBDEs, the hatching rate and DNA damage of stage 7 embryos were also measured. PBDEs had no significant impact on the hatching rate and DNA damage of grass shrimp in most experimental conditions regardless of embryo developmental stage or UV exposure, but in the case of UV-exposed BDE-47, the hatching rate was decreased, suggesting a potential reproductive toxicity. This research is meaningful because it is the first study to propose that PBDEs can cause reproductive toxicity in marine organism, after flowing into the ocean and undergoing photochemical reactions stimulated by UV.
authors.affiliation: Department of Marine Environmental Engineering, Institute of Marine Industry, Gyeongsang National University, Tongyeong 650-160, Republic of Korea.
authors.forename: Hyo Jin
authors.initials: HJ
authors.lastname: Lee
authors.forename: Gi Beum
authors.initials: GB
authors.lastname: Kim
authors.forename: Richard F
authors.initials: RF
authors.lastname: Lee
mesh_terms: D000818:Animals; D004249:DNA Damage; D004625:Embryo, Nonmammalian / Q000187:drug effects*; D005260:Female; D005411:Flame Retardants / Q000633:toxicity*; D048788:Growth and Development / Q000187:drug effects; D055768:Halogenated Diphenyl Ethers / Q000633:toxicity*; D009153:Mutagens / Q000633:toxicity; D033541:Palaemonidae / Q000196:embryology*; D011075:Polybrominated Biphenyls / Q000633:toxicity; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D005411:Flame Retardants; D055768:Halogenated Diphenyl Ethers; D009153:Mutagens; D011075:Polybrominated Biphenyls; D014874:Water Pollutants, Chemical; C511295:2,2',4,4'-tetrabromodiphenyl ether