title: A general intramolecular Friedel-Crafts approach to functionalized pyrrolo[3,2,1-ij]quinolin-4-ones.
abstract: An indium(III)-catalyzed intramolecular Friedel-Crafts annulation for the efficient synthesis of pyrrolo[3,2,1-ij]quinolin-4-ones is described. The products are formed in good to excellent yields (51-97%) with diastereoselectivities up to >99 : 1 dr.
authors.affiliation: School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia, USA.
authors.forename: Dadasaheb V
authors.initials: DV
authors.lastname: Patil
authors.forename: Marchello A
authors.initials: MA
authors.lastname: Cavitt
authors.forename: Paul
authors.initials: P
authors.lastname: Grzybowski
authors.forename: Stefan
authors.initials: S
authors.lastname: France
mesh_terms: D002384:Catalysis; D007204:Indium / Q000737:chemistry*; D015394:Molecular Structure; D011758:Pyrroles / Q000138:chemical synthesis* / Q000737:chemistry; D015363:Quinolones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D011758:Pyrroles; D015363:Quinolones; D007204:Indium