title: Rapid multiorgan dissemination of low-grade myxofibrosarcoma: a case report.
abstract: Myxofibrosarcoma is one of the most common sarcomas in the extremities of elderly people. It is characterized by a high frequency of local recurrence due to an infiltrative growth property. In contrast, the overall risk of distant metastases is generally low. This makes the prognosis for the patients with myxofibrosarcoma definitely good. In this paper, we will report the case of a 79-year-old female with very aggressive metastatic low-grade myxofibrosarcoma. The disease progression was really unexpected and misled every possible medical interpretation, leading to rapid worsening of the patient's clinical conditions and no chance for therapy. The tumor developed diffuse infiltration in lung, spine, skeletal bone, abdomen, paravertebral muscles, and liver. The patient died 8 months after the diagnosis of remote metastases due to rapid tumor progression.
authors.affiliation: Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo, Hokkaido 060-8543, Japan.
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Murahashi
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Kaya
authors.forename: Tamotsu
authors.initials: T
authors.lastname: Soma
authors.forename: Mikito
authors.initials: M
authors.lastname: Sasaki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nagoya
authors.forename: Takuro
authors.initials: T
authors.lastname: Wada
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Yamashita