title: Pseudo-pseudo Meigs' syndrome in a patient with systemic lupus erythematosus.
abstract: Pseudo-pseudo Meigs' syndrome (PPMS) is a rare manifestation of patients with systemic lupus erythematosus (SLE), defined by the presence of ascites, pleural effusions and an elevated CA-125 level. We describe a patient with longstanding lupus who presented with localized lymphadenopathy and subsequently developed massive chylous ascites with marked hypoalbuminemia. A brief historical overview of Meigs' syndrome and related entities is presented, along with a discussion of the differential diagnosis of hypoalbuminemia and ascites in an SLE patient. In addition, we speculate on the optimal therapeutic intervention in such a patient.
authors.affiliation: Division of Rheumatology, NYU Hospital for Joint Diseases, USA. Samir.dalvi@duke.edu
authors.forename: S R
authors.initials: SR
authors.lastname: Dalvi
authors.forename: R
authors.initials: R
authors.lastname: Yildirim
authors.forename: D
authors.initials: D
authors.lastname: Santoriello
authors.forename: H M
authors.initials: HM
authors.lastname: Belmont
mesh_terms: D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D018394:CA-125 Antigen / Q000097:blood; D002915:Chylous Ascites / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D034141:Hypoalbuminemia / Q000209:etiology; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008206:Lymphatic Diseases / Q000209:etiology; D008539:Meigs Syndrome / Q000175:diagnosis; D008875:Middle Aged; D019152:Paracentesis; D010996:Pleural Effusion / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D011237:Predictive Value of Tests; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D015854:Up-Regulation
chemical_list: D015415:Biomarkers; D018394:CA-125 Antigen; D007166:Immunosuppressive Agents