title: Noninvasive estimation of the blood pressure waveform in the carotid artery using continuous finger blood pressure monitoring.
abstract: To noninvasively estimate the blood pressure continuously in the common carotid artery (CCA), we obtained the distension waveform of the CCA from seven healthy volunteers and 20 hypertensive patients using radio-frequency ultrasound. Consequently, it was calibrated by the mean and diastolic pressure measured in the finger artery and compared with applanation tonometry, calibrated using the systolic and diastolic pressure in the brachial artery. The mean difference in estimating the mean blood pressure was 0.3 mm Hg (limits of agreement: -11.7 to 12.3 mm Hg). In estimating the systolic blood pressure, the mean difference was 8.0 mm Hg (limits of agreement: -29.8 to 45.8 mm Hg) and showed increasing variation with blood pressure. The systolic blood pressure values can be expected between 0.83 and 1.35 times the control method. In this study, we obtained proof-of-principle for noninvasively measuring blood pressure in the CCA using continuous finger blood pressure monitoring. This opens the way to estimating location specific arterial stiffness and intra-plaque elasticity.
authors.affiliation: Radboud University Nijmegen Medical Centre, Clinical Physics Laboratory, Nijmegen, The Netherlands. t.idzenga@rad.umcn.nl
authors.forename: Tim
authors.initials: T
authors.lastname: Idzenga
authors.forename: Koen D
authors.initials: KD
authors.lastname: Reesink
authors.forename: Youri
authors.initials: Y
authors.lastname: van Swelm
authors.forename: Hendrik H G
authors.initials: HH
authors.lastname: Hansen
authors.forename: Suzanne
authors.initials: S
authors.lastname: Holewijn
authors.forename: Chris L
authors.initials: CL
authors.lastname: de Korte
mesh_terms: D000328:Adult; D062186:Arterial Pressure; D001795:Blood Pressure Determination / Q000379:methods*; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005260:Female; D005385:Fingers / Q000098:blood supply / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014463:Ultrasonography / Q000379:methods*; D055815:Young Adult