title: Condition-specific quality of life 24 months after retropubic and transobturator sling surgery for stress urinary incontinence.
abstract: OBJECTIVE
  To compare quality of life (QoL) and factors associated with QoL change after retropubic (RMUS) and transobturator midurethral slings (TMUS) using the Incontinence Impact Questionnaire (IIQ) and the International Consultation on Incontinence Questionnaire (ICIQ).
  
  
  METHODS
  Five hundred ninety-seven women in a multicenter randomized trial of RMUS versus TMUS were examined. The IIQ and the ICIQ were obtained at baseline and at 12 and 24 months. Repeated-measures analysis of variance tested for differences by treatment group over time. Multivariable analysis identified factors associated with QoL change at 12 months postoperative, controlling for treatment group and baseline QoL.
  
  
  RESULTS
  Improvement in IIQ was associated with the following: treatment success, younger age, improvement in stress urinary incontinence (SUI) symptom severity, and bother (all P < 0.05). Improvement in ICIQ was associated with treatment success, younger age, improvement in SUI symptom severity and bother, lower body mass index, and no reoperation (all P < 0.05). Improvement of the IIQ was stable over time (P = 0.35) for both treatment groups (P = 0.66), whereas the ICIQ showed a small but clinically insignificant decline (P = 0.03) in both treatment groups (P = 0.51).
  
  
  CONCLUSIONS
  Postoperative QoL was improved after RMUS and TMUS. Measures of QoL functioned similarly, although more surgically modifiable urinary incontinence factors predicted improvement with the IIQ.
authors.affiliation: Department of Urology, William Beaumont Hospital, Royal Oak, MI, USA. Lsirls@mac.com
authors.forename: Larry T
authors.initials: LT
authors.lastname: Sirls
authors.forename: Sharon
authors.initials: S
authors.lastname: Tennstedt
authors.forename: Emily
authors.initials: E
authors.lastname: Lukacz
authors.forename: Leslie
authors.initials: L
authors.lastname: Rickey
authors.forename: Stephen R
authors.initials: SR
authors.lastname: Kraus
authors.forename: Alayne D
authors.initials: AD
authors.lastname: Markland
authors.forename: Kimberly
authors.initials: K
authors.lastname: Kenton
authors.forename: Pam
authors.initials: P
authors.lastname: Moalli
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Hsu
authors.forename: Liyuan
authors.initials: L
authors.lastname: Huang
authors.forename: Anne M
authors.initials: AM
authors.lastname: Stoddard
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008875:Middle Aged; D011184:Postoperative Period; D019919:Prosthesis Implantation / Q000379:methods*; D011788:Quality of Life; D053825:Suburethral Slings; D011795:Surveys and Questionnaires; D014550:Urinary Incontinence, Stress / Q000601:surgery*