title: Stages of early acute renal dysfunction in liver transplantation: the influence of graft function.
abstract: The development of early acute renal dysfunction (eARD) occurring in the first week after orthotopic liver transplantation (OLT) is mainly influenced by more severe degrees of pre-OLT hepatic insufficiency and liver graft dysfunction. The aim of our study was to evaluate the incidence of eARD post-OLT as well as its association with pre- and post-OLT hepatic dysfunction. We selected 54 end-stage liver disease patients who underwent OLT from 2008 to 2011. The prevalence of eARD was 53.7% (29/54) classified according to AKIN criteria in ARD-Risk (55.2%), ARD-Injury (27.6%) and ARD-Failure (17.2%). The worst stage of post-OLT eARD (eARD-Failure) seems to be influenced by the poor pre-OLT hepatic function as well as by early suboptimal recovery of graft function.
authors.affiliation: Department of Clinical Medicine, Nephrology and Dialysis Unit, 1st Faculty of Medicine and Surgery, Sapienza University of Rome, Rome, Italy.
authors.forename: I
authors.initials: I
authors.lastname: Umbro
authors.forename: M
authors.initials: M
authors.lastname: Rossi
authors.forename: F
authors.initials: F
authors.lastname: Tinti
authors.forename: F
authors.initials: F
authors.lastname: Fiacco
authors.forename: P
authors.initials: P
authors.lastname: Piselli
authors.forename: S
authors.initials: S
authors.lastname: Ianni
authors.forename: S
authors.initials: S
authors.lastname: Ginanni Corradini
authors.forename: L
authors.initials: L
authors.lastname: Poli
authors.forename: P B
authors.initials: PB
authors.lastname: Berloco
authors.forename: A P
authors.initials: AP
authors.lastname: Mitterhofer
mesh_terms: D058625:End Stage Liver Disease / Q000601:surgery*; D006084:Graft Rejection; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D016031:Liver Transplantation