title: Assessment of in vitro skin irritation potential of nanoparticles: RHE model.
abstract: The skin irritation test is designed for the prediction of acute skin irritation of nanoparticles by measurement of its cytotoxic effect, as reflected in the MTT assay, on the Reconstructed Human Epidermis (RHE) model. RHE tissues are commercially available.
authors.affiliation: International Institute for Biotechnology and Toxicology (IIBAT), Kancheepuram, Tamil Nadu, India. director@iibat.com
authors.forename: P Balakrishna
authors.initials: PB
authors.lastname: Murthy
authors.forename: A Sairam
authors.initials: AS
authors.lastname: Kishore
authors.forename: P
authors.initials: P
authors.lastname: Surekha
mesh_terms: D000042:Absorption / Q000187:drug effects; D000287:Administration, Topical; D002021:Buffers; D003470:Culture Media; D004817:Epidermis / Q000187:drug effects*; D006801:Humans; D066298:In Vitro Techniques; D008954:Models, Biological; D053758:Nanoparticles / Q000008:administration & dosage / Q000633:toxicity*; D012685:Sepharose; D023422:Skin Irritancy Tests / Q000379:methods*
chemical_list: D002021:Buffers; D003470:Culture Media; D012685:Sepharose