title: Rearranged benzophenones and prenylated xanthones from Garcinia propinqua twigs.
abstract: The first phytochemical investigation of Garcinia propinqua has led to the isolation and identification of three new compounds, including two rearranged benzophenones, doitunggarcinones A (1) and B (2), and a xanthone, doitunggarcinone C (3), together with seven known compounds (4-10). The structures of 1-3 were elucidated on the basis of spectroscopic methods, including UV, IR, NMR, and MS. The antibacterial activity of the 10 isolates was evaluated against Escherichia coli TISTR 780, Salmonella typhimurium TISTR 292, Staphylococcus aureus TISTR 1466, and methicillin-resistant Staphylococcus aureus (MRSA) SK1.
authors.affiliation: Natural Products Research Laboratory, School of Science, Mae Fah Luang University, Tasud, Muang, Chiang Rai 57100, Thailand.
authors.forename: Cholpisut
authors.initials: C
authors.lastname: Tantapakul
authors.forename: Wong
authors.initials: W
authors.lastname: Phakhodee
authors.forename: Thunwadee
authors.initials: T
authors.lastname: Ritthiwigrom
authors.forename: Sarot
authors.initials: S
authors.lastname: Cheenpracha
authors.forename: Uma
authors.initials: U
authors.lastname: Prawat
authors.forename: Suwanna
authors.initials: S
authors.lastname: Deachathai
authors.forename: Surat
authors.initials: S
authors.lastname: Laphookhieo
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001577:Benzophenones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029760:Garcinia / Q000737:chemistry*; D016106:Methicillin Resistance / Q000187:drug effects; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018547:Plant Stems / Q000737:chemistry; D054876:Prenylation; D013211:Staphylococcus aureus / Q000187:drug effects; D013785:Thailand; D044004:Xanthones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D001577:Benzophenones; D044004:Xanthones; C577393:doitunggarcinone A; C577392:doitunggarcinone B; C577394:doitunggarcinone C