title: Synthesis of quinoline derivatives for fluorescent imaging certain bacteria.
abstract: Highly fluorescent quinoline derivatives were synthesized using Sc(OTf)(3) catalyzed imino Diels-Alder reaction. Both the aromatic and their analogous tetradehydroquinoline derivatives were explored for the detection of bacteria using fluorescent imaging studies. Surprisingly the aromatic quinoline derivatives show a remarkable fluorescent response that can be useful in the detection of both gram positive and gram negative bacteria even at a concentration in the range of 0.078 mM.
authors.affiliation: Sathyabama University, Jeppiaarnagar, Chennai, India.
authors.forename: Ramu
authors.initials: R
authors.lastname: Dhanapal
authors.forename: Paramasivan T
authors.initials: PT
authors.lastname: Perumal
authors.forename: Munusamy
authors.initials: M
authors.lastname: Damodiran
authors.forename: Chandrasekaran
authors.initials: C
authors.lastname: Ramprasath
authors.forename: Narayanasamy
authors.initials: N
authors.lastname: Mathivanan
mesh_terms: D001412:Bacillus subtilis / Q000302:isolation & purification*; D061565:Cycloaddition Reaction; D004926:Escherichia coli / Q000302:isolation & purification*; D005456:Fluorescent Dyes / Q000032:analysis* / Q000138:chemical synthesis; D008856:Microscopy, Fluorescence; D011804:Quinolines / Q000032:analysis* / Q000138:chemical synthesis; D013050:Spectrometry, Fluorescence; D013211:Staphylococcus aureus / Q000302:isolation & purification*
chemical_list: D005456:Fluorescent Dyes; D011804:Quinolines