title: Malignant pilomatrixoma arising on the previously irradiated face: case report and literature review.
abstract: BACKGROUND
  Malignant pilomatrixoma (also known as pilomatrix carcinoma) is a very rare malignant neoplasm derived from the hair matrix. These slow-growing malignancies of the skin are found in the lower dermis and subcutaneous fat layer. They can exhibit local aggressive behavior or distant metastasis. This malignancy can arise as a solitary lesion de novo or through transformation of a pilomatrixoma over a long period. There is no known distinct etiologic factor or predisposing condition for this kind of malignancy.
  
  
  CONCLUSIONS
  We present an interesting case of a 65-year-old man with a pilomatrix carcinoma arising on the previously irradiated face due to the malignant neoplasm of the parotid gland. This is the first report of a pilomatrix carcinoma that has developed on a region that has undergone radiotherapy for another malignancy.
authors.affiliation: Department of Plastic, Aesthetic and Reconstructive Surgery, Ataturk Training & Research Hospital, Izmir, Turkey. drokaraaslan@yahoo.com
authors.forename: Onder
authors.initials: O
authors.lastname: Karaaslan
authors.forename: Murat
authors.initials: M
authors.lastname: Melih Can
authors.forename: Ayse
authors.initials: A
authors.lastname: Ozlem Karatas Silistreli
authors.forename: Yagmur
authors.initials: Y
authors.lastname: Kaan Bedir
authors.forename: Gorkem
authors.initials: G
authors.lastname: Caliskan
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005145:Face / Q000528:radiation effects*; D005500:Follow-Up Studies; D006201:Hair Diseases / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D006801:Humans; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D010307:Parotid Neoplasms / Q000532:radiotherapy; D018296:Pilomatrixoma / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery