title: Biocompatible magnetic liposomes for temperature triggered drug delivery.
abstract: Thermosensitive magnetic liposomes (TSMLs) that serve as carriers for controlled drug release are fabricated. The TSMLs are stable below 39 °C and most drugs (5-(and-6)-carboxylfluorescein: 68% and doxorubicin: 90%) release within 1 h at 42 °C. Furthermore, TSMLs could deliver the anticancer drugs into cells to induce cell apoptosis.
authors.affiliation: Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing, PR China.
authors.forename: Xingwei
authors.initials: X
authors.lastname: Ding
authors.forename: Kaiyong
authors.initials: K
authors.lastname: Cai
authors.forename: Zhong
authors.initials: Z
authors.lastname: Luo
authors.forename: Jinghua
authors.initials: J
authors.lastname: Li
authors.forename: Yan
authors.initials: Y
authors.lastname: Hu
authors.forename: Xinkun
authors.initials: X
authors.lastname: Shen
mesh_terms: D017209:Apoptosis / Q000187:drug effects; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004317:Doxorubicin / Q000008:administration & dosage / Q000737:chemistry / Q000493:pharmacokinetics; D016503:Drug Delivery Systems / Q000379:methods*; D005452:Fluoresceins; D006801:Humans; D008081:Liposomes / Q000008:administration & dosage* / Q000737:chemistry / Q000493:pharmacokinetics; D058185:Magnetite Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry*; D008422:Materials Testing; D013696:Temperature
chemical_list: D005452:Fluoresceins; D008081:Liposomes; D058185:Magnetite Nanoparticles; D004317:Doxorubicin