title: Gemtuzumab-induced orchitis in a patient with refractory acute promyelocytic leukaemia.
abstract: We report the case of a 22-year-old Saudi male patient who was treated extensively in the past with various regimens for acute promyelocytic leukaemia that was refractory to all standard treatments. He was ultimately administered Gemtuzumab to induce remission and subjected to an allogeneic bone marrow transplant. However, he developed orchitis, which has not been previously reported with this agent.
authors.affiliation: Department of Oncology, King Faisal Specialist Hospital and Research Centre, Jeddah, Kingdom of Saudi Arabia. jaliljeddah@yahoo.com
authors.lastname: Jalil-ur-Rehman
authors.forename: Muhammad
authors.initials: M
authors.lastname: Kelta
authors.forename: Khalid
authors.initials: K
authors.lastname: Awad
authors.forename: Basim Al
authors.initials: BA
authors.lastname: Beirouti
authors.forename: Shahzad
authors.initials: S
authors.lastname: Nasser
authors.forename: Muhammad
authors.initials: M
authors.lastname: Aslam
mesh_terms: D000617:Aminoglycosides / Q000009:adverse effects* / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized / Q000009:adverse effects* / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000079982:Gemtuzumab; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy*; D008297:Male; D009920:Orchitis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D012074:Remission Induction; D016896:Treatment Outcome; D018608:Ultrasonography, Doppler; D055815:Young Adult
chemical_list: D000617:Aminoglycosides; D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D000079982:Gemtuzumab