title: Electrically induced lipid migration in non-lamellar phase.
abstract: Inverted hexagonal blocks of 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) lipid adsorbed on a polyethyleneimine (PEI)-coated surface in deionized water transformed its shape upon the application of an electric field, forming lipid objects in a variety of shapes (e.g. lines with a width of 10-50 μm). The phenomenon was driven by the electrophoresis, because the zwitterionic lipid, DOPE turned out to be highly negatively charged in deionized water. The interaction between DOPE and the PEI surface stabilized the system, assuring a lifetime over several weeks for the formed structures after the electric field was switched off. The free-drawing of microscopic objects (lines, crosses, and jelly fish) was also achieved by controlling the direction of the lipid movement with the field direction.
authors.affiliation: Laboratory of Biosensors and Bioelectronics, Institute for Biomedical Engineering, ETH Zurich, Zurich, Switzerland. sugihara@is.mpg.de
authors.forename: Kaori
authors.initials: K
authors.lastname: Sugihara
authors.forename: Janick
authors.initials: J
authors.lastname: Stucki
authors.forename: Lucio
authors.initials: L
authors.lastname: Isa
authors.forename: János
authors.initials: J
authors.lastname: Vörös
authors.forename: Tomaso
authors.initials: T
authors.lastname: Zambelli
mesh_terms: D004553:Electric Conductivity; D004586:Electrophoresis; D008081:Liposomes / Q000737:chemistry*; D010714:Phosphatidylethanolamines / Q000737:chemistry
chemical_list: D008081:Liposomes; D010714:Phosphatidylethanolamines; C020888:1,2-dielaidoylphosphatidylethanolamine