title: Sexual function and quality of life after surgical treatment for anal fistulas in Crohn's disease.
abstract: BACKGROUND
  The aim of this study was to assess sexual function and quality of life (QoL) in patients after surgery for perianal Crohn's disease.
  
  
  METHODS
  Eighty-eight consecutive patients with perianal Crohn's disease, operated on at the Medical University of Vienna, completed a self-administered questionnaire including the International Index of Erectile Function (IIEF), Female Sexual Function Index (FSFI), Short Form-12 Health Survey (SF-12), and the Inflammatory Bowel Disease Questionnaire (IBDQ). Patients with a current stoma were excluded from further analysis. The median follow-up time was 104 months (range 3-186 months). Healthy subjects served as controls for each case and were matched by age (±6 years) and gender. Forty-seven (68 %) female and 22 male patients with a median age of 46.5 years (range 18-64 years) were analyzed. Eleven (16 %) patients had simple and 58 (84 %) complex anal fistulas.
  
  
  RESULTS
  The median SF-12 physical health score of the patients was significantly lower (47.9 (range 25.5-57.2)) than that of the controls (54.3 (range 34.6-61.8); p = 0.03). Not surprisingly, the median total sore of the IBDQ of the controls was significantly better than that of the patients (controls: 188.5 (range 125-206.5), patients: 157 (range 60-199.5); p < 0.0001). Analysis with the multiple logistic regression test showed that type of operation, >1 perianal fistula opening, and active Crohn's disease were independent risk factors for a worse IBDQ (p = 0.03, p = 0.015 and p < 0.0001). Interestingly, the median FSFI and IIEF score were not found to be significant different in any domain.
  
  
  CONCLUSIONS
  QoL but not sexual function is significantly influenced by surgery for perianal Crohn's disease.
authors.affiliation: Department of General Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. stefan.riss@meduniwien.ac.at
authors.forename: S
authors.initials: S
authors.lastname: Riss
authors.forename: K
authors.initials: K
authors.lastname: Schwameis
authors.forename: M
authors.initials: M
authors.lastname: Mittlböck
authors.forename: M
authors.initials: M
authors.lastname: Pones
authors.forename: H
authors.initials: H
authors.lastname: Vogelsang
authors.forename: W
authors.initials: W
authors.lastname: Reinisch
authors.forename: M
authors.initials: M
authors.lastname: Riedl
authors.forename: A
authors.initials: A
authors.lastname: Stift
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D003424:Crohn Disease / Q000150:complications; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*; D011788:Quality of Life; D012003:Rectal Fistula / Q000209:etiology / Q000601:surgery*; D012307:Risk Factors; D012720:Severity of Illness Index; D012725:Sexual Behavior; D012735:Sexual Dysfunction, Physiological / Q000209:etiology*; D020018:Sexual Dysfunctions, Psychological / Q000209:etiology*; D011795:Surveys and Questionnaires; D055815:Young Adult