title: A biphasic tumor consisting of pilocytic astrocytoma with an anaplastic solitary fibrous tumor component in the pineal region: a case report and literature review.
abstract: Here we report a case of a biphasic tumor consisting of pilocytic astrocytoma with anaplastic solitary fibrous tumor component in the pineal region. The majority of the tumor showed typical histologic features of pilocytic astrocytoma. A minor part of the tumor showed marked proliferation of short spindle cells around vessels. These spindle cells showed CD34 and CD99 immunoreactivity. From a review of the literature, we found that only one similar case has been reported. Contrary to the reported case, our case showed anaplastic features of solitary fibrous tumor histology.
authors.affiliation: Departments of Pathology, Yonsei University, Seoul, Korea.
authors.forename: Seon Jung
authors.initials: SJ
authors.lastname: Jang
authors.forename: Jinna
authors.initials: J
authors.lastname: Kim
authors.forename: Jin Mo
authors.initials: JM
authors.lastname: Cho
authors.forename: SongMi
authors.initials: S
authors.lastname: Noh
authors.forename: Sung-Hye
authors.initials: SH
authors.lastname: Park
authors.forename: Se Hoon
authors.initials: SH
authors.lastname: Kim
mesh_terms: D000071443:12E7 Antigen; D015703:Antigens, CD / Q000378:metabolism; D018952:Antigens, CD34 / Q000378:metabolism; D001254:Astrocytoma / Q000473:pathology* / Q000628:therapy; D002277:Carcinoma / Q000473:pathology* / Q000628:therapy; D015815:Cell Adhesion Molecules / Q000378:metabolism; D059248:Chemoradiotherapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D018218:Neoplasms, Fibrous Tissue / Q000473:pathology* / Q000628:therapy; D019635:Neurosurgical Procedures / Q000379:methods; D010871:Pinealoma / Q000473:pathology* / Q000628:therapy
chemical_list: D000071443:12E7 Antigen; D015703:Antigens, CD; D018952:Antigens, CD34; C061828:CD99 protein, human; D015815:Cell Adhesion Molecules