title: A novel non-linear recursive filter design for extracting high rate pulse features in nuclear medicine imaging and spectroscopy.
abstract: Applications in imaging and spectroscopy rely on pulse processing methods for appropriate data generation. Often, the particular method utilized does not highly impact data quality, whereas in some scenarios, such as in the presence of high count rates or high frequency pulses, this issue merits extra consideration. In the present study, a new approach for pulse processing in nuclear medicine imaging and spectroscopy is introduced and evaluated. The new non-linear recursive filter (NLRF) performs nonlinear processing of the input signal and extracts the main pulse characteristics, having the powerful ability to recover pulses that would ordinarily result in pulse pile-up. The filter design defines sampling frequencies lower than the Nyquist frequency. In the literature, for systems involving NaI(Tl) detectors and photomultiplier tubes (PMTs), with a signal bandwidth considered as 15 MHz, the sampling frequency should be at least 30 MHz (the Nyquist rate), whereas in the present work, a sampling rate of 3.3 MHz was shown to yield very promising results. This was obtained by exploiting the known shape feature instead of utilizing a general sampling algorithm. The simulation and experimental results show that the proposed filter enhances count rates in spectroscopy. With this filter, the system behaves almost identically as a general pulse detection system with a dead time considerably reduced to the new sampling time (300 ns). Furthermore, because of its unique feature for determining exact event times, the method could prove very useful in time-of-flight PET imaging.
authors.affiliation: Medical Imaging Systems Group, Research Center for Molecular and Cellular Imaging, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Salar
authors.initials: S
authors.lastname: Sajedi
authors.forename: Alireza
authors.initials: A
authors.lastname: Kamal Asl
authors.forename: Mohammad R
authors.initials: MR
authors.lastname: Ay
authors.forename: Mohammad H
authors.initials: MH
authors.lastname: Farahani
authors.forename: Arman
authors.initials: A
authors.lastname: Rahmim
mesh_terms: D000465:Algorithms; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D017711:Nonlinear Dynamics; D009683:Nuclear Medicine; D049268:Positron-Emission Tomography / Q000379:methods*; D013057:Spectrum Analysis