title: Structure characterization of a novel neutral polysaccharide isolated from Ganoderma lucidum fruiting bodies.
abstract: Ganoderma lucidum (G. lucidum) is a mushroom which has been used for health promotion for a long time in China. In the present work a neutral hetero-polysaccharide, named FYGL-1, was isolated from FYGL which was reported previously capable of antihyperglycemia in vivo for further detailed chemical structure investigation. The results of monosaccharide composition and GPC analysis indicated that FYGL-1 consisted of galactose, rhamnose and glucose in mole ratio of 1.00:1.15:3.22 with a molecular weight of 78kDa. The detailed structure of FYGL-1 was characterized by periodate oxidation, Smith degradation, methylation analysis, along with FT-IR, GC, GC-MS, 1D (1)H and (13)C NMR and 2D NMR (HSQC, COSY, NOESY and TOCSY). Based on the analysis of the results, the structure of the repeating unit of FYGL-1 was established as:
authors.affiliation: State Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 200433, PR China.
authors.forename: Deng
authors.initials: D
authors.lastname: Pan
authors.forename: Linqiang
authors.initials: L
authors.lastname: Wang
authors.forename: Congheng
authors.initials: C
authors.lastname: Chen
authors.forename: Baosong
authors.initials: B
authors.lastname: Teng
authors.forename: Chendong
authors.initials: C
authors.lastname: Wang
authors.forename: Zhixue
authors.initials: Z
authors.lastname: Xu
authors.forename: Bingwen
authors.initials: B
authors.lastname: Hu
authors.forename: Ping
authors.initials: P
authors.lastname: Zhou
mesh_terms: D002240:Carbohydrate Sequence; D048690:Fruiting Bodies, Fungal / Q000737:chemistry* / Q000254:growth & development; D008969:Molecular Sequence Data; D015394:Molecular Structure; D011134:Polysaccharides / Q000737:chemistry* / Q000302:isolation & purification; D020940:Reishi / Q000737:chemistry* / Q000254:growth & development
chemical_list: D011134:Polysaccharides