title: Seasonality of staphylococcal infections.
abstract: Characterization of seasonal variation of Staphylococcus aureus is important in understanding the epidemiology of, and designing preventive strategies against this highly virulent and ever-evolving pathogen. In this review, we summarize the findings of epidemiological studies that have evaluated seasonality in S. aureus colonization and infection. Although most studies published to date are methodologically weak, some seasonal variation in the occurrence of S. aureus infection appears to exist, particularly an association of warm-weather months with S. aureus skin and soft-tissue infections. We highlight the limitations of the published literature, and provide suggestions for future studies on this topic.
authors.affiliation: Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD 21201, USA. sleekha@epi.umaryland.edu
authors.forename: S
authors.initials: S
authors.lastname: Leekha
authors.forename: D J
authors.initials: DJ
authors.lastname: Diekema
authors.forename: E N
authors.initials: EN
authors.lastname: Perencevich
mesh_terms: D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification; D012621:Seasons; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology