title: Small-incision lenticule extraction for moderate to high myopia: Predictability, safety, and patient satisfaction.
abstract: OBJECTIVE
  To present initial clinical experience with small-incision lenticule extraction for the treatment of moderate to high myopia.
  
  
  METHODS
  Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.
  
  
  METHODS
  Prospective clinical study.
  
  
  METHODS
  For small-incision lenticule extraction, an intrastromal lenticule was cut with a femtosecond laser and manually extracted without creation of a flap. Patients were treated and followed for 3 months. Only 1 randomly chosen eye of each patient was used in the statistical analyses.
  
  
  RESULTS
  The study enrolled 144 patients. The mean preoperative spherical equivalent was -7.18 diopters (D) ± 1.57 (SD). Of eyes with emmetropia as target refraction, 40% had an uncorrected distance visual acuity of 0.1 logMAR or less 1 day after surgery; this increased to 73% at 3 months. The mean corrected distance visual acuity (CDVA) improved significantly from -0.01 (logMAR) preoperatively to -0.03 3 months postoperatively. None of the 127 eyes lost 2 lines or more of CDVA and 6 eyes lost 1 line of CDVA after 3 months. In contrast, 1 eye gained 2 lines and 24 eyes gained 1 line of CDVA. The achieved refraction was a mean of -0.09 ± 0.45 D from the attempted refraction. Of the eyes, 77% were within ±0.50 D and 95% were within ±1.00 D. Ninety-five percent of the patients would recommend the procedure to others.
  
  
  CONCLUSIONS
  The refractive predictability, safety, and patient satisfaction 3 months after small-incision lenticule extraction were high and comparable to results in previous studies of femtosecond laser-assisted techniques.
  
  
  BACKGROUND
  Drs. Hjortdal and Asp received travel reimbursement from Carl Zeiss Meditec AG, Jena, Germany. No other author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: Department of Ophthalmology, Aarhus University Hospital, Aarhus, Denmark.
authors.forename: Anders
authors.initials: A
authors.lastname: Vestergaard
authors.forename: Anders R
authors.initials: AR
authors.lastname: Ivarsen
authors.forename: Sven
authors.initials: S
authors.lastname: Asp
authors.forename: Jesper Ø
authors.initials: JØ
authors.lastname: Hjortdal
mesh_terms: D000328:Adult; D003319:Corneal Stroma / Q000601:surgery*; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008866:Microsurgery / Q000379:methods; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000503:physiopathology / Q000601:surgery*; D017060:Patient Satisfaction; D011446:Prospective Studies; D012029:Refraction, Ocular / Q000502:physiology; D015203:Reproducibility of Results; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult