title: Effect of metabotropic receptor agonists on ionic current of snail neurons.
abstract: The dose-dependent and reversible changes of sodium (I(Na)), calcium (I(ca)), slow potassium (I(Ks)), and fast potassium (I(Kf)) currents were recorded in isolated snail neurons under the action of κ-opioid agonist butorphanol and chemical agent RU-1203 applied in a concentration range of 1-1000 μM.
authors.affiliation: Volgograd State Medical University, Ministry of Health Care and Social Development of the Russian Federation, Rostov-on-Don, Russia. olesiagrechko@mail.ru
authors.forename: O Yu
authors.initials: OY
authors.lastname: Grechko
authors.forename: A A
authors.initials: AA
authors.lastname: Spasov
authors.forename: A I
authors.initials: AI
authors.lastname: Vislobokov
authors.forename: Yu D
authors.initials: YD
authors.lastname: Ignatov
authors.forename: V A
authors.initials: VA
authors.lastname: Anisimova
mesh_terms: D000818:Animals; D002077:Butorphanol / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism; D002463:Cell Membrane Permeability / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D008564:Membrane Potentials / Q000187:drug effects*; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D018408:Patch-Clamp Techniques; D011188:Potassium / Q000378:metabolism; D017473:Receptors, Opioid, kappa / Q000819:agonists*; D012908:Snails; D015222:Sodium Channels / Q000378:metabolism
chemical_list: D017473:Receptors, Opioid, kappa; D015222:Sodium Channels; D002077:Butorphanol; D011188:Potassium; D002118:Calcium