title: Changes and their prognostic implications in the abbreviated Vitalpac™ early warning score (ViEWS) after admission to hospital of 18,853 acutely ill medical patients.
abstract: BACKGROUND
  The best performing early warning score is Vitalpac™ Early Warning Score (ViEWS). However, it is not known how often, to what extent and over what time frame any early warning scores change, and what the implications of these changes are.
  
  
  METHODS
  Thunder Bay Regional Health Sciences Center, Ontario, Canada.
  
  
  METHODS
  The changes in the first three complete sets of the six variables required to retrospectively calculate the abbreviated version of ViEWS (that did not include mental status) after admission to hospital of 18,853 acutely ill medical patients, and their relationship to subsequent in-hospital mortality were examined.
  
  
  RESULTS
  In the 10.4 SD 20.1 (median 5.0) hours between admission and the second recording the score changed in only 5.9% of patients and these changes were of no prognostic value. By the time of the third recording 34.9 SD 21.7 (median 30.0) hours after admission a change in score was clearly associated with a corresponding change in in-hospital mortality (e.g. for patients with an initial score of 5 an increase between the first and third recording of ≥4 points was associated with an increased mortality (OR 6.5 95% CI 2.3-15.9, p<0.00001), whereas a reduction of ≤-4 points was associated with a reduced mortality (OR 0.4 95% CI 0.2-0.9, p 0.03)).
  
  
  CONCLUSIONS
  After a median interval of 30 h both the initial abbreviated ViEWS recording and subsequent changes in it both predict clinical outcome. It remains to be determined what interventions during this time frame will improve patient outcomes.
authors.affiliation: Thunder Bay Regional Health Sciences Center, Thunder Bay, Ontario, Canada. jgkellett@eircom.net
authors.forename: John
authors.initials: J
authors.lastname: Kellett
authors.forename: Simon
authors.initials: S
authors.lastname: Woodworth
authors.forename: Fei
authors.initials: F
authors.lastname: Wang
authors.forename: Wendy
authors.initials: W
authors.lastname: Huang
mesh_terms: D000208:Acute Disease; D000368:Aged; D016009:Chi-Square Distribution; D005260:Female; D006305:Health Status Indicators; D017052:Hospital Mortality; D006801:Humans; D007297:Inpatients; D008297:Male; D008875:Middle Aged; D009864:Ontario / Q000453:epidemiology; D010343:Patient Admission; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012720:Severity of Illness Index; D055986:Vital Signs