title: Synthesis of Novel Core Cross-Linked Star-Based Polyrotaxane End-Capped via "CuAAC" Click Chemistry.
abstract: The first example of core cross-linked star (CCS) polyrotaxane was prepared using the poly(ϵ-caprolactone) (PCL) CCS three-dimensional (3D) scaffold. The 3D CCS polymer was firstly prepared through the "arm-first" approach. Then, the "arms" of the resultant PCL CCS polymer were threaded with α-cyclodextrins (α-CDs). The threaded α-CDs were permanently locked by the "click" reaction of terminal alkyne functionalities of the star polymers with the azide-functionalized end caps to afford the CCS polyrotaxanes. All analytical results confirm the formation of the CCS polyrotaxanes and reveal their characteristics, including fluorescence under UV, a channel-type crystalline structure, a two-step thermal decomposition, and a unique core-shell structure in great contrast to the polymer precursors.
authors.affiliation: Polymer Science Group, Department of Chemical and Biomolecular Engineering, The University of Melbourne, Melbourne 3010, Australia.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Fu
authors.affiliation: Polymer Science Group, Department of Chemical and Biomolecular Engineering, The University of Melbourne, Melbourne 3010, Australia.
authors.forename: Jing M
authors.initials: JM
authors.lastname: Ren
authors.affiliation: Polymer Science Group, Department of Chemical and Biomolecular Engineering, The University of Melbourne, Melbourne 3010, Australia.
authors.forename: Shereen
authors.initials: S
authors.lastname: Tan
authors.affiliation: Polymer Science Group, Department of Chemical and Biomolecular Engineering, The University of Melbourne, Melbourne 3010, Australia.
authors.forename: Jiangtao
authors.initials: J
authors.lastname: Xu
authors.affiliation: Polymer Science Group, Department of Chemical and Biomolecular Engineering, The University of Melbourne, Melbourne 3010, Australia. gregghq@unimelb.edu.au.
authors.forename: Greg G
authors.initials: GG
authors.lastname: Qiao
mesh_terms: D000480:Alkynes / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D057930:Click Chemistry; D003505:Cyclodextrins / Q000138:chemical synthesis*; D004337:Drug Carriers; D020442:Poloxamer / Q000138:chemical synthesis*; D011091:Polyesters / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D043862:Rotaxanes / Q000138:chemical synthesis*; D014466:Ultraviolet Rays; D047391:alpha-Cyclodextrins / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001386:Azides; D003505:Cyclodextrins; D004337:Drug Carriers; D011091:Polyesters; D043862:Rotaxanes; D047391:alpha-Cyclodextrins; C475673:polyrotaxane; D020442:Poloxamer; C016240:polycaprolactone; D011092:Polyethylene Glycols