title: Enantioselective decarboxylative amination: synthesis of axially chiral allenyl amines.
abstract: Getting axed: synthesis of the title amines, bearing functionality (R(1) and R(2)), involves the enantioselective palladium-catalyzed decarboxylation of allenyl N-tosylcarbamates. The reaction proceeds smoothly using both the chiral ligands (S)- and (R)-DTBM-Segphos (1) to afford the allenyl amines in good yields and with high enantioseletivities.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, PR China.
authors.forename: Baoqiang
authors.initials: B
authors.lastname: Wan
authors.forename: Shengming
authors.initials: S
authors.lastname: Ma
mesh_terms: D000466:Alkadienes / Q000138:chemical synthesis* / Q000737:chemistry; D000586:Amination; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D003653:Decarboxylation; D013237:Stereoisomerism
chemical_list: D000466:Alkadienes; D000588:Amines; C025947:propadiene