title: Enhanced luminescence of lanthanide complexes by silver nanoparticles for ciprofloxacin determination.
abstract: We present the enhancement of luminescence of europium complex, Eu(3+)-ciprofloxacin (CIP), in the presence of silver nanoparticles (Ag NPs) for the CIP determination. The increment of the luminescence intensity of the Eu(3+)-CIP complex with Ag NPs was obtained due to the transfer of resonance energy to the fluorophores through the interaction of the excited-state fluorophores and surface plasmon electron in the metal nano surface. The luminescence intensity of Eu3+ was enhanced by complexation with CIP at 614 nm after excitation at 373 nm corresponding to the 5D0-7F2 transitions of Eu3+ ion. Based on the above phenomenon, a sensitive and rapid spectrofluorimetric method has been developed for the CIP determination. Linearity of the calibration curve was obtained in the range of 2.0 x 10(-10)-1.0 x 10(-8) g mL(-1) with correlation coefficient of 0.9992. The limit of detection of CIP was found to be 1.9 x 10(-11) g mL(-1) with the relative standard deviation (RSD) of 1.19% for 5 replicate measurements of 5.0 x 10(-7) g mL(-1) of CIP. The present method has been successfully applied for CIP determination in pharmaceutical and biological samples.
authors.affiliation: Department of Chemistry, Kyungpook National University, Daegu, 702-701, South Korea.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Kamruzzaman
authors.forename: Al-Mahmnur
authors.initials: AM
authors.lastname: Alam
authors.forename: Kyung Min
authors.initials: KM
authors.lastname: Kim
authors.forename: Sang Hak
authors.initials: SH
authors.lastname: Lee
authors.forename: Yeoun Suk
authors.initials: YS
authors.lastname: Suh
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Kim
authors.forename: Sung Hong
authors.initials: SH
authors.lastname: Kim
authors.forename: Sang Hyub
authors.initials: SH
authors.lastname: Oh
mesh_terms: D000890:Anti-Infective Agents / Q000032:analysis; D015374:Biosensing Techniques / Q000295:instrumentation*; D002939:Ciprofloxacin / Q000032:analysis*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D008163:Luminescent Measurements / Q000295:instrumentation*; D053768:Metal Nanoparticles / Q000737:chemistry*; D020349:Surface Plasmon Resonance / Q000295:instrumentation*
chemical_list: D000890:Anti-Infective Agents; D028581:Lanthanoid Series Elements; D002939:Ciprofloxacin