title: CSF kynurenic acid and suicide risk in schizophrenia spectrum psychosis.
abstract: Relationships between concentrations of cerebrospinal fluid (CSF) kynurenic acid (KYNA) and suicidal behavior were evaluated in 59 patients with psychosis after 22 years of follow-up. Three patients died from suicide and nine patients had a history of attempted suicide. Patients with attempted suicide had significantly lower concentrations of CSF KYNA.
authors.affiliation: Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Karolinska University Hospital Solna, SE-171 76 Stockholm, Sweden. andreas.carlborg@sll.se
authors.forename: Andreas
authors.initials: A
authors.lastname: Carlborg
authors.forename: Jussi
authors.initials: J
authors.lastname: Jokinen
authors.forename: Erik G
authors.initials: EG
authors.lastname: Jönsson
authors.forename: Sophie
authors.initials: S
authors.lastname: Erhardt
authors.forename: Peter
authors.initials: P
authors.lastname: Nordström
mesh_terms: D000293:Adolescent; D000328:Adult; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007736:Kynurenic Acid / Q000134:cerebrospinal fluid*; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D011618:Psychotic Disorders / Q000134:cerebrospinal fluid* / Q000401:mortality; D018570:Risk Assessment; D012559:Schizophrenia / Q000134:cerebrospinal fluid* / Q000401:mortality; D013405:Suicide; D013406:Suicide, Attempted; D055815:Young Adult
chemical_list: D007736:Kynurenic Acid