title: Prophylactic versus therapeutic amnioinfusion for oligohydramnios in labour.
abstract: BACKGROUND
  Amnioinfusion aims to relieve umbilical cord compression during labour by infusing a liquid into the uterine cavity.
  
  
  OBJECTIVE
  The objective of this review was to assess the effects of prophylactic amnioinfusion for women in labour with oligohydramnios, but not fetal heart deceleration, compared with therapeutic amnioinfusion only if fetal heart rate decelerations or thick meconium-staining of the liquor occur.
  
  
  METHODS
  We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (28 February 2012).
  
  
  METHODS
  Randomised trials comparing prophylactic amnioinfusion in women in labour with oligohydramnios but not fetal heart rate deceleration in labour with therapeutic amnioinfusion.
  
  
  METHODS
  The authors assessed trial quality and extracted data.
  
  
  RESULTS
  One randomized trial of 116 women was included. No differences were found in the rate of caesarean section (risk ratio 1.29, 95% confidence interval 0.60 to 2.74). There were no differences in cord arterial pH, oxytocin augmentation, neonatal pneumonia or postpartum endometritis. Prophylactic amnioinfusion was associated with increased intrapartum fever (risk ratio 3.48, 95% confidence interval 1.21 to 10.05).
  
  
  CONCLUSIONS
  There appears to be no advantage of prophylactic amnioinfusion over therapeutic amnioinfusion carried out only when fetal heart rate decelerations or thick meconium-staining of the liquor occur.
authors.affiliation: Department of Obstetrics and Gynaecology, East London Hospital Complex, Walter Sisulu University, East London, South Africa.
authors.forename: Natalia
authors.initials: N
authors.lastname: Novikova
authors.forename: G Justus
authors.initials: GJ
authors.lastname: Hofmeyr
authors.forename: George
authors.initials: G
authors.lastname: Essilfie-Appiah
mesh_terms: D000650:Amnion; D005260:Female; D005316:Fetal Distress / Q000628:therapy; D005318:Fetal Heart / Q000503:physiopathology*; D006340:Heart Rate, Fetal / Q000502:physiology*; D006801:Humans; D007267:Injections; D007744:Obstetric Labor Complications / Q000517:prevention & control / Q000628:therapy*; D016104:Oligohydramnios / Q000517:prevention & control / Q000628:therapy*; D011247:Pregnancy; D016032:Randomized Controlled Trials as Topic