title: [Analyzing Chinese medicine syndromes of hematotoxicity reaction induced by highly active antiretroviral therapy].
abstract: OBJECTIVE
  To investigate the main features of Chinese medicine (CM) syndromes and differences of hematotoxicity reaction induced by highly active antiretroviral therapy.
  
  
  METHODS
  The information of CM four diagnostic methods was collected by cross-sectional study. Their syndrome features were summed up and their differences were analyzed.
  
  
  RESULTS
  Of the 216 patients, the main syndromes were qi-blood deficiency syndrome (142 cases, accounting for 65.7%) and Pi-Shen yang deficiency syndrome (74 cases, accounting for 34.3%). The score of qi-blood deficiency syndrome was obviously lower than that of Pi-Shen yang deficiency syndrome (P < 0.05). The count of CD4+ T cells was higher in qi-blood deficiency syndrome than in Pi-Shen yang deficiency syndrome. There was no statistical difference in the serum viral load between the two groups (P > 0.05). The quality of life was higher in qi-blood deficiency syndrome than in Pi-Shen yang deficiency syndrome, but with no statistical difference (P > 0.05).
  
  
  CONCLUSIONS
  Qi-blood deficiency syndrome and Pi-Shen yang deficiency syndrome were main syndromes of hematotoxicity reaction induced by HAART. The pathogenic condition of qi-blood deficiency syndrome patients was milder. There was no obvious difference in the quality of life, CD4+ T cells, and the viral loads between two syndromes.
authors.affiliation: AIDS Treatment and Research Center, First Affiliated Hospital of Henan College of Traditional Chinese Medicine, Zhengzhou.
authors.forename: Zhi-Bin
authors.initials: ZB
authors.lastname: Liu
authors.forename: Xiu-Min
authors.initials: XM
authors.lastname: Chen
authors.forename: Yan-Tao
authors.initials: YT
authors.lastname: Jin
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D000328:Adult; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D018791:CD4 Lymphocyte Count; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D011788:Quality of Life; D019562:Viral Load; D016711:Yang Deficiency / Q000175:diagnosis; D016710:Yin Deficiency / Q000175:diagnosis