title: Evidence-based practice: management of glottic cancer.
abstract: The main issue in the management of glottic squamous cell carcinoma, as for all cancers, is adequate disease control while optimizing functional outcomes and minimizing morbidity. This is true for early-stage disease as for advanced tumors. This article evaluates the current evidence for the diagnostic and pretherapeutic workup for glottic squamous cell carcinoma and the evidence concerning different treatment options for glottic carcinoma, from early-stage to advanced-stage disease.
authors.affiliation: Department of Head and Neck Oncology, Institut Gustave Roussy, Villejuif, France. dana.hartl@igr.fr
authors.forename: Dana M
authors.initials: DM
authors.lastname: Hartl
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D017024:Chemotherapy, Adjuvant / Q000379:methods / Q000706:statistics & numerical data; D003131:Combined Modality Therapy; D019468:Disease Management; D018572:Disease-Free Survival; D055317:Evidence-Based Practice; D005931:Glottis / Q000473:pathology / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D037981:Neck Dissection / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D060787:Neoplasm Grading; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D013517:Otorhinolaryngologic Surgical Procedures / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D011379:Prognosis; D018714:Radiotherapy, Adjuvant / Q000379:methods / Q000706:statistics & numerical data; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome