title: Open injuries of the lower extremity: issues and unknown frontiers.
authors.forename: Shanmuganathan
authors.initials: S
authors.lastname: Rajasekaran
authors.forename: Peter V
authors.initials: PV
authors.lastname: Giannoudis
mesh_terms: D000671:Amputation, Surgical / Q000706:statistics & numerical data*; D015415:Biomarkers / Q000097:blood; D003906:Developing Countries; D006233:Persons with Disabilities / Q000706:statistics & numerical data*; D005260:Female; D005597:Fractures, Open / Q000097:blood / Q000453:epidemiology* / Q000601:surgery; D006801:Humans; D015994:Incidence; D007194:India; D015601:Injury Severity Score; D015850:Interleukin-6 / Q000097:blood; D019344:Lactic Acid / Q000097:blood; D007869:Leg Injuries / Q000175:diagnosis / Q000628:therapy; D023821:Limb Salvage; D035002:Lower Extremity / Q000293:injuries; D008297:Male
chemical_list: D015415:Biomarkers; D015850:Interleukin-6; D019344:Lactic Acid