title: Blood flow simulation and vascular reconstruction.
abstract: In medical practice, bypass grafts are commonly used as an alternative route around strongly stenosed or occluded arteries. In contrast to arterial bifurcations, surgically created anastomosis can be modified with the objective of enabling optimal graft geometry to yield a flow environment that improves its longevity. This paper presents a three dimensional numerical study of blood flow through bypass systems with different geometries. Coupled with the finite element solver a shape optimization framework considering a genetic algorithm is presented. Numerical results show the benefits of understanding blood flow hemodynamic at anastomosis junctions achieving design improvements. Minimizing recirculation zones and flow stagnation can be useful in surgical planning.
authors.affiliation: Department of Mechanical Engineering, FEUP, University of Porto, Porto, Portugal. lcsousa@fe.up.pt
authors.forename: Luisa Costa
authors.initials: LC
authors.lastname: Sousa
authors.forename: Catarina F
authors.initials: CF
authors.lastname: Castro
authors.forename: Carlos Conceição
authors.initials: CC
authors.lastname: António
authors.forename: Rui
authors.initials: R
authors.lastname: Chaves
mesh_terms: D000714:Anastomosis, Surgical; D001157:Arterial Occlusive Diseases / Q000503:physiopathology*; D001158:Arteries / Q000503:physiopathology*; D001775:Blood Circulation / Q000502:physiology*; D003198:Computer Simulation; D020342:Finite Element Analysis; D006439:Hemodynamics; D006801:Humans; D008955:Models, Cardiovascular