title: Comprehensive approaches to managing delirium in patients with advanced cancer.
abstract: Delirium is a frequently under-recognized complication in patients with advanced cancer. Uncontrolled delirium eventually leads to significant distress to patients and their families. However, delirium episodes can be reversed in half of these patients by eliminating precipitating factors and using appropriate interventions. The purpose of this narrative review is to discuss the most recent updates in the literature on the management of delirium in patients with advanced cancer. This article addresses the epidemiology, cause, pathophysiology, clinical characteristics, and assessment of delirium as well as various treatment options, including nonpharmacologic intervention and palliative sedation.
authors.affiliation: Department of Palliative Care and Rehabilitation Medicine, The University of Texas MD Anderson Cancer Center, USA.
authors.forename: Jung Hun
authors.initials: JH
authors.lastname: Kang
authors.forename: Seong Hoon
authors.initials: SH
authors.lastname: Shin
authors.forename: Eduardo
authors.initials: E
authors.lastname: Bruera
mesh_terms: D003693:Delirium / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D009369:Neoplasms / Q000150:complications*