title: Investigation of auditory processing disorder and language impairment using the speech-evoked auditory brainstem response.
abstract: This study investigated whether there are differences in the Speech-Evoked Auditory Brainstem Response among children with Typical Development (TD), (Central) Auditory Processing Disorder (C)APD, and Language Impairment (LI). The speech-evoked Auditory Brainstem Response was tested in 57 children (ages 6-12). The children were placed into three groups: TD (n = 18), (C)APD (n = 18) and LI (n = 21). Speech-evoked ABR were elicited using the five-formant syllable/da/. Three dimensions were defined for analysis, including timing, harmonics, and pitch. A comparative analysis of the responses between the typical development children and children with (C)APD and LI revealed abnormal encoding of the speech acoustic features that are characteristics of speech perception in children with (C)APD and LI, although the two groups differed in their abnormalities. While the children with (C)APD might had a greater difficulty distinguishing stimuli based on timing cues, the children with LI had the additional difficulty of distinguishing speech harmonics, which are important to the identification of speech sounds. These data suggested that an inefficient representation of crucial components of speech sounds may contribute to the difficulties with language processing found in children with LI. Furthermore, these findings may indicate that the neural processes mediated by the auditory brainstem differ among children with auditory processing and speech-language disorders.
authors.affiliation: Universidade de São Paulo School of Medicine, São Paulo, Brazil. carolrocha@usp.br
authors.forename: Caroline N
authors.initials: CN
authors.lastname: Rocha-Muniz
authors.forename: Debora M
authors.initials: DM
authors.lastname: Befi-Lopes
authors.forename: Eliane
authors.initials: E
authors.lastname: Schochat
mesh_terms: D000161:Acoustic Stimulation; D001306:Auditory Pathways / Q000503:physiopathology; D001308:Auditory Perceptual Disorders / Q000503:physiopathology*; D016022:Case-Control Studies; D002648:Child; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D006801:Humans; D007805:Language Development Disorders / Q000503:physiopathology*; D008297:Male; D010700:Phonetics