title: Fabrication of organic electrochemical transistor arrays for biosensing.
abstract: BACKGROUND
  Organic electrochemical transistors (OECT) have been used as various types of biosensors with very high sensitivity. The OECTs show advantages of easy fabrication, low operational voltage, excellent flexibility and biocompatibility.
  
  
  METHODS
  OECT arrays based on poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) were fabricated in poly(ethylene glycol) (PEG) microwells by physical delamination.
  
  
  RESULTS
  The OECTs show fast response time, stable channel current and excellent transistor characteristics. The PEG microwells can be used to trap cells on top of the OECTs, which will be important for the application of the OECT arrays as cell-based biosensors.
  
  
  CONCLUSIONS
  This technique provides a feasible way for high-throughput cell analysis based on transistor arrays. This article is part of a Special Issue entitled Organic Bioelectronics-Novel Applications in Biomedicine.
authors.affiliation: Department of Applied Physics and Materials Research Centre, The Hong Kong Polytechnic University, Hong Kong, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Zhang
authors.forename: Peng
authors.initials: P
authors.lastname: Lin
authors.forename: Mo
authors.initials: M
authors.lastname: Yang
authors.forename: Feng
authors.initials: F
authors.lastname: Yan
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods*; D045744:Cell Line, Tumor; D004563:Electrochemistry / Q000295:instrumentation* / Q000379:methods*; D056945:Hep G2 Cells; D006801:Humans; D011092:Polyethylene Glycols / Q000737:chemistry; D011137:Polystyrenes / Q000737:chemistry; D013876:Thiophenes / Q000737:chemistry; D014173:Transistors, Electronic
chemical_list: D011137:Polystyrenes; D013876:Thiophenes; C533756:poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate); D011092:Polyethylene Glycols