title: Four new coumarinolignoids from seeds of Solanum indicum.
abstract: Activity-guided fractionation of seeds of Solanum indicum for anti-HBV activity led to the isolation of two novel coumarinolignoid alkaloids (indicumines A-B, 1-2) and two new coumarinolignoids (indicumines C-D, 3-4), together with four known coumarins (5-8). Their structures were established on the basis of spectroscopic data. The two novel coumarinolignoid alkaloids shows anti-HBV activities through specifically inhibiting the secretion of HBsAg in HepG2.2.15.
authors.affiliation: Beijing University of Technology, Beijing 100124, China.
authors.forename: Hai-Long
authors.initials: HL
authors.lastname: Yin
authors.forename: Jie-Hui
authors.initials: JH
authors.lastname: Li
authors.forename: Jian
authors.initials: J
authors.lastname: Li
authors.forename: Bin
authors.initials: B
authors.lastname: Li
authors.forename: Li
authors.initials: L
authors.lastname: Chen
authors.forename: Yin
authors.initials: Y
authors.lastname: Tian
authors.forename: Shi-Jun
authors.initials: SJ
authors.lastname: Liu
authors.forename: Tao
authors.initials: T
authors.lastname: Zhang
authors.forename: Jun-Xing
authors.initials: JX
authors.lastname: Dong
mesh_terms: D000818:Animals; D003374:Coumarins / Q000737:chemistry*; D015394:Molecular Structure; D012639:Seeds / Q000737:chemistry*; D032322:Solanum / Q000737:chemistry*
chemical_list: D003374:Coumarins