title: Zoster sine herpete, vertebral artery stenosis, and ischemic stroke.
abstract: Although a previous or recent history of varicella-zoster virus (VZV) infection is known to increase the risk of stroke in both children and adults, the influence of zoster sine herpetic remains unclear. We report an immunocompetent man with common cold symptoms and conjunctivitis, followed by an acute onset of bulbar weakness and hemihypesthesia without preceding skin rash. Acute medullary infarction and left vertebral artery stenosis were detected. VZV infection was finally identified. Zoster sine herpetic interferes with accurate diagnosis of infectious stroke, and vertebral artery involvement is unusual in ischemic stroke in this situation. An unexplained course of ischemic stroke event should be suspected in patients with VZV cerebrovasculopathy, especially in those without conventional stroke risk factors and those exhibiting concomitant infectious complications.
authors.affiliation: Department of Neurology, Kaohsiung Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Kaohsiung, Taiwan; Graduate Institute of Technology and Law, National First University of Science and Technology, Kaohsiung, Taiwan.
authors.forename: Wei-Hsi
authors.initials: WH
authors.lastname: Chen
authors.forename: Chi
authors.initials: C
authors.lastname: Chui
authors.forename: Hsin-Ling
authors.initials: HL
authors.lastname: Yin
mesh_terms: D000328:Adult; D002545:Brain Ischemia / Q000150:complications*; D006801:Humans; D008297:Male; D020521:Stroke / Q000150:complications*; D014715:Vertebrobasilar Insufficiency / Q000150:complications*; D031368:Zoster Sine Herpete / Q000150:complications*