title: Gaining a comprehensive understanding of pruritus.
abstract: Pruritus is a common symptom associated with many dermatoses, systemic abnormalities, and psychiatric / psychosomatic diseases. Additionally, pruritus is one of the most intractable symptoms due to its complex pathogenesis involving an increasing number of mediators and receptors, undefined neurophysiologic pathways, unclear cerebral processing, and psychophysiology interaction. Clinically, the first challenge of dermatologists is how to get general and interdisciplinary vision of pruritus and to preliminarily figure it out whether there might be underlying systemic or psychosocial disorders. The second challenge is to select efficient individual tailored anti-pruritic treatment, which includes targeted drugs and cognitive-behavioral therapy.
authors.affiliation: Department of Dermatology, No. 2 Hospital of Jilin University, Changchun, China.
authors.forename: Haiiao
authors.initials: H
authors.lastname: Zhang
authors.forename: Yi
authors.initials: Y
authors.lastname: Yang
authors.forename: Jiuwei
authors.initials: J
authors.lastname: Cui
authors.forename: Yaqin
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000982:Antipruritics / Q000627:therapeutic use; D002779:Cholestasis / Q000150:complications; D015928:Cognitive Behavioral Therapy; D006801:Humans; D007674:Kidney Diseases / Q000150:complications; D001523:Mental Disorders / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D009369:Neoplasms / Q000150:complications*; D009422:Nervous System Diseases / Q000150:complications*; D011087:Polycythemia Vera / Q000150:complications; D011537:Pruritus / Q000209:etiology* / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D011602:Psychophysiologic Disorders / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D012871:Skin Diseases / Q000150:complications
chemical_list: D000982:Antipruritics