title: Genetic diversity of internalin genes in the ascB-dapE locus among Listeria monocytogenes lineages III and IV strains.
abstract: Listeria monocytogenes is an important foodborne pathogen encompassing four phylogenetic lineages. Lineages III and IV are rare, but have been reported to show considerable biodiversity, providing important clues for the evolutionary history in Listeria. In this study, analysis of the ascB-dapE locus reveals genetic diversity in lineages III and IV, and is consistent with the classification of sublineages. Four of the six genetic patterns (two of sublineage IIIC and two of lineage IV) are specific to these two lineages. The ascB-dapE locus suggests a hot spot for genome diversification, and serves as an attractive molecular marker for better understanding of the biodiversity and population structure of lineages III and IV strains.
authors.affiliation: Zhejiang Fisheries Technical Extension Center, and Zhejiang Aquatic Disease Prevention and Quarantine Center, Hangzhou, Zhejiang, P.R. China.
authors.forename: Jianshun
authors.initials: J
authors.lastname: Chen
authors.forename: Changyong
authors.initials: C
authors.lastname: Cheng
authors.forename: Yonghui
authors.initials: Y
authors.lastname: Lv
authors.forename: Weihuan
authors.initials: W
authors.lastname: Fang
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D016000:Cluster Analysis; D023061:Gene Order; D014644:Genetic Variation; D008089:Listeria monocytogenes / Q000145:classification* / Q000235:genetics*; D010802:Phylogeny; D017422:Sequence Analysis, DNA
chemical_list: D001426:Bacterial Proteins; C069761:internalin protein, Bacteria