title: Apoptosis as a mechanism of maxillary sinus mucosa injury in rats after experimental transection of the maxillary nerve.
abstract: Transection of the maxillary nerve initiates apoptosis of the maxillary sinus mucosa cells in rats. Significant activation of apoptosis and proapoptotic factor p53 was found in the epithelium during week 1 after nerve transection. In delayed period after injury, apoptotic cells predominated in the submucosa against the background of Bcl-2 hypoexpression.
authors.affiliation: Department of Histology, Vladivostok State Medical University, Russian Ministry of Health, Russia. mobilestom@yandex.ru
authors.forename: S S
authors.initials: SS
authors.lastname: Edranov
authors.forename: P A
authors.initials: PA
authors.lastname: Motavkin
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D007150:Immunohistochemistry; D020287:In Situ Nick-End Labeling; D008442:Maxillary Nerve / Q000293:injuries / Q000503:physiopathology*; D008443:Maxillary Sinus / Q000166:cytology* / Q000293:injuries; D009297:Nasal Mucosa / Q000293:injuries*; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism; D051381:Rats; D061221:Trigeminal Nerve Injuries / Q000503:physiopathology*; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism
chemical_list: D019253:Proto-Oncogene Proteins c-bcl-2; D016159:Tumor Suppressor Protein p53