title: [Update of the usefulness of α-blockers in the treatment of different urologic pathologies].
abstract: OBJECTIVE
  To review the role of α-blockers in various urological conditions such as benign prostatic hyperplasia, overactive bladder, chronic prostatitis, and erectile dysfunction and as expulsive treatment of distal ureteral stones.
  
  
  METHODS
  We reviewed the latest scientific evidence in all the fields mentioned above, performing a critical analysis.
  
  
  CONCLUSIONS
  α-blockers are now considered first-line treatment in lower urinary tract symptoms secondary to benign prostatic hyperplasia, but the indications go beyond, and are able to improve, alone or in combination with other drugs, the previously mentioned pathologies. The uroselective properties of some α-blockers make them a highly safe medication.
authors.affiliation: Servicio de Urología, Hospital General Universitario Gregorio Marañón, Madrid, Spain. chernandez.hgugm@salud.madrid.org
authors.forename: Carlos
authors.initials: C
authors.lastname: Hernández Fernández
authors.forename: Francisco
authors.initials: F
authors.lastname: Brenes Bermúdez
authors.forename: Ignacio
authors.initials: I
authors.lastname: Moncada Iribarren
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D000368:Aged; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D015897:Comorbidity; D007172:Erectile Dysfunction / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D009130:Muscle, Smooth / Q000187:drug effects; D011470:Prostatic Hyperplasia / Q000150:complications; D011472:Prostatitis / Q000188:drug therapy; D014514:Ureteral Calculi / Q000188:drug therapy; D001743:Urinary Bladder / Q000187:drug effects; D053201:Urinary Bladder, Overactive / Q000188:drug therapy; D014555:Urination Disorders / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology
chemical_list: D000317:Adrenergic alpha-Antagonists