title: Epidemiology and trend of cancer in Isfahan 2005-2010.
abstract: BACKGROUND
  Cancer incidence rate is increasing in the world particularly in developing countries. The awareness regarding cancer incidence and distribution helps policy makers and researchers to design comprehensive plan for controlling cancer. The aim of this study was to determine the incidence rate and trend of cancer in Isfahan area, one of the most importance provinces of Iran.
  
  
  METHODS
  Data of Isfahan cancer registry were derived from 2005 to 2010. Direct standardization through world standard population produced by the world health organization was used and adjusted standard rate (ASR) was calculated. The Poisson regression analysis was employed to estimate cancer incidence trend during 5 years.
  
  
  RESULTS
  The new cases of cancer were 24771 patients from 2005 to 2010. Mean age of these patients was 56.1 ± 18.0 years and 54.6% were male. Male patients were approximately 7 years older than females. The most frequent cancer was gastrointestinal in men and breast cancer in women. The rate of cancer increased approximately 4 per 1000 population and incidence rate ratio (IRR) was 1.004 (95%CI: 1.002-1.005).
  
  
  CONCLUSIONS
  The rate of cancer is increasing rapidly in Isfahan province. Cancer control and comprehensive prevention plan for Isfahan is necessary.
authors.affiliation: Assistant Professor, Department of Clinical Oncology, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Fariborz
authors.initials: F
authors.lastname: Mokarian
authors.forename: Mohammad Arash
authors.initials: MA
authors.lastname: Ramezani
authors.forename: Kamal
authors.initials: K
authors.lastname: Heydari
authors.forename: Maryam
authors.initials: M
authors.lastname: Tabatabaeian
authors.forename: Hossein
authors.initials: H
authors.lastname: Tavazohi