title: Rheumatoid arthritis: Threshold for success in RA drug development.
abstract: Determining the potential success of investigational therapies for rheumatoid arthritis early in the development process would enable better allocation of increasingly limited resources. Such ‘go or no-go’ decision-making could be improved by a method of analysing longitudinal clinical trial data to establish a threshold for success of a new drug.
authors.affiliation: Metroplex Clinical Research Center, 8144 Walnut Hill Lane, Dallas, TX 75231, USA. scohen@arthdocs.com.
authors.forename: Stanley B
authors.initials: SB
authors.lastname: Cohen
mesh_terms: D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D003661:Decision Support Techniques; D017277:Drug Approval; D006801:Humans; D015201:Meta-Analysis as Topic; D016032:Randomized Controlled Trials as Topic