title: Combining time of flight and diffraction tomography for high resolution breast imaging: initial in vivo results (L).
abstract: Ultrasound tomography (UST) is being developed to address the limitations of mammography in breast cancer detection. Central to the success of UST is the possibility of obtaining high-resolution images of tissue mechanical properties across the whole breast. A recent paper [Huthwaite and Simonetti, J. Acoust. Soc. Am. 130, 1721-1734 (2011)] made use of a numerical phantom to demonstrate that sufficient image resolution can be obtained by simply treating refraction and diffraction effects in consecutive steps through the combination of ray-based time of flight and diffraction tomography. This letter presents the first experimental demonstration of the method using phantom and invivo data from a cancer patient.
authors.affiliation: Department of Mechanical Engineering, Imperial College, London, SW7 2AZ, United Kingdom.
authors.forename: P
authors.initials: P
authors.lastname: Huthwaite
authors.forename: F
authors.initials: F
authors.lastname: Simonetti
authors.forename: N
authors.initials: N
authors.lastname: Duric
mesh_terms: D000465:Algorithms; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D019047:Phantoms, Imaging; D011237:Predictive Value of Tests; D016217:Ultrasonography, Mammary / Q000295:instrumentation