title: Further validation of multiple sclerosis walking scale-12 scores based on spatiotemporal gait parameters.
abstract: OBJECTIVE
  To examine the association between Multiple Sclerosis Walking Scale-12 (MSWS-12) scores and spatiotemporal parameters of gait as indicators of gait quality among ambulatory persons with multiple sclerosis (MS).
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  University research laboratory.
  
  
  METHODS
  Community-residing persons with MS (N=268).
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  Main outcome measures included the MSWS-12 and spatial and temporal gait parameters (walking speed, cadence, step length, step time, base of support [ie, the distance between 1 footfall and the line of progression of the opposing foot], and percentage of gait cycle spent in double support). Secondary outcomes included the timed 25-foot walk (T25FW), 6-minute walk (6MW), and Patient-Determined Disease Steps scale.
  
  
  RESULTS
  MSWS-12 scores were significantly correlated with walking speed (r=-.59), cadence (r=-.50), step length (r=-.53), step time (r=.46), base of support (r=.29), and percentage of the gait cycle spent in double support (r=.54). MSWS-12 scores further were significantly correlated with T25FW (r=.57) and 6MW (r=-.75) scores.
  
  
  CONCLUSIONS
  Such findings suggest that the MSWS-12 captures aspects of walking quality, assessed as spatiotemporal parameters of gait, in addition to walking speed and endurance in persons with MS.
authors.affiliation: Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
authors.forename: Lara A
authors.initials: LA
authors.lastname: Pilutti
authors.forename: Deirdre
authors.initials: D
authors.lastname: Dlugonski
authors.forename: Brian M
authors.initials: BM
authors.lastname: Sandroff
authors.forename: Yoojin
authors.initials: Y
authors.lastname: Suh
authors.forename: John H
authors.initials: JH
authors.lastname: Pula
authors.forename: Jacob J
authors.initials: JJ
authors.lastname: Sosnoff
authors.forename: Robert W
authors.initials: RW
authors.lastname: Motl
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D004185:Disability Evaluation; D005260:Female; D020233:Gait Disorders, Neurologic / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000503:physiopathology*