title: Bullous pyoderma gangrenosum: a case report and review of the published work.
abstract: Pyoderma gangrenosum (PG) is an ulcerative skin disorder characterized by neutrophilic infiltrations. PG is generally classified into four types: (i) ulcerative; (ii) pustular; (iii) bullous; and (iv) vegetative. Among them, bullous PG is known as a rare type. Herein, we report a case of bullous PG together with a summary of the 12 PG cases treated in our department over the previous 15 years, and we review 38 well-documented bullous PG cases (65.8% female; aged 18-80 years [mean ± standard deviation, 51.6 ± 16.8]) in the published work, including the present case, from 1972-2011. Although the disease most frequently associated with PG is inflammatory bowel disease, bullous PG is most commonly associated with hematological disorders (25/38, 65.8%), which indicates the characteristic pathophysiology specific to bullous PG.
authors.affiliation: Department of Dermatology, National Defense Medical College, Tokorozawa, Japan. sakki2622@yahoo.co.jp
authors.forename: Masayuki
authors.initials: M
authors.lastname: Sakiyama
authors.forename: Takashi
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Yuiko
authors.initials: Y
authors.lastname: Nagata
authors.forename: Norihiro
authors.initials: N
authors.lastname: Fujimoto
authors.forename: Takahiro
authors.initials: T
authors.lastname: Satoh
authors.forename: Shingo
authors.initials: S
authors.lastname: Tajima
mesh_terms: D000328:Adult; D001768:Blister / Q000473:pathology*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007866:Leg / Q000473:pathology; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000188:drug therapy / Q000473:pathology*
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone