title: A novel methylated sesquiterpene from seagrass Posidonia oceanica (L.) Delile.
abstract: Phytochemical investigation of chloroform extract from the leaves of the marine plant Posidonia oceanica (L.) Delile (Posidoniaceae), yielded posidozinol, a new methylated sesquiterpene along with β-sitosterol and four known fatty acids: palmitic, palmitoleic, oleic and linoleic acids. The structure elucidation has been established on the basis of 1D- and 2D-NMR spectroscopy, GS/MS and ES mass spectrometry. Antibacterial effects of crude extracts from P. oceanica were evaluated against: Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis and Micrococcus luteus microorganisms.
authors.affiliation: Unité de Recherche 12-04, Chimie Appliquée et Environnement, Faculté des Sciences de Monastir, University of Monastir, 5000 Monastir, Tunisie.
authors.forename: Saoussen
authors.initials: S
authors.lastname: Hammami
authors.forename: Abdelkader Ben
authors.initials: AB
authors.lastname: Salem
authors.forename: Mohamed L
authors.initials: ML
authors.lastname: Ashour
authors.forename: Jihène
authors.initials: J
authors.lastname: Cheriaa
authors.forename: Guella
authors.initials: G
authors.lastname: Graziano
authors.forename: Zine
authors.initials: Z
authors.lastname: Mighri
mesh_terms: D035961:Alismatales / Q000737:chemistry*; D002725:Chloroform; D002855:Chromatography, Thin Layer; D015169:Colony Count, Microbial; D052978:Disk Diffusion Antimicrobial Tests; D004926:Escherichia coli / Q000187:drug effects; D005227:Fatty Acids / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008745:Methylation; D016982:Micrococcus luteus / Q000187:drug effects; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D012855:Sitosterols / Q000302:isolation & purification; D013210:Staphylococcus / Q000187:drug effects
chemical_list: D005227:Fatty Acids; D010936:Plant Extracts; D012717:Sesquiterpenes; D012855:Sitosterols; C025473:gamma-sitosterol; D002725:Chloroform