title: An infrared spectroscopic tool for process monitoring: sugar contents during the production of a depilatory formulation.
abstract: A fast, reliable and economical methodology has been developed to control the production process of sugar-based depilatories. The method is based on the use of attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy in combination with multivariate data analysis. A very simple sample preparation process involving the dissolution of samples in water was applied. Employing a multivariate calibration model established from data of 15 well characterized samples, prediction errors equal or below 3.04 mg mL(-1) for the quantitative determination of fructose, glucose, sucrose, maltose and maltotriose were obtained. Results found in this preliminary study indicate a great potential for the development of at-line ATR-FTIR-PLS methods based on a careful selection of variables from IR spectra, delivering fast and reliable results. As a reference method, a liquid chromatography (LC)-IR method was adapted for sample characterization.
authors.affiliation: Department of Analytical Chemistry, University of Valencia Edificio Jerónimo Muñoz, 50th Dr. Moliner, 46100 Burjassot, Spain.
authors.forename: Julia
authors.initials: J
authors.lastname: Kuligowski
authors.forename: Mercedes
authors.initials: M
authors.lastname: Cascant
authors.forename: Salvador
authors.initials: S
authors.lastname: Garrigues
authors.forename: Miguel
authors.initials: M
authors.lastname: de la Guardia
mesh_terms: D002241:Carbohydrates / Q000032:analysis*; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D016018:Least-Squares Analysis; D015999:Multivariate Analysis; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods*; D014867:Water / Q000737:chemistry
chemical_list: D002241:Carbohydrates; D014867:Water