title: Enhanced frontoparietal network architectures following "gaze-contingent" versus "free-hand" motor learning.
abstract: Longitudinal changes in cortical function are known to accompany motor skills learning, and can be detected as an evolution in the activation map. These changes include attenuation in activation in the prefrontal cortex and increased activation in primary and secondary motor regions, the cerebellum and posterior parietal cortex. Despite this, comparatively little is known regarding the impact of the mode or type of training on the speed of activation map plasticity and on longitudinal variation in network architectures. To address this, we randomised twenty-one subjects to learn a complex motor tracking task delivered across six practice sessions in either "free-hand" or "gaze-contingent motor control" mode, during which frontoparietal cortical function was evaluated using functional near infrared spectroscopy. Results demonstrate that upon practice termination, gaze-assisted learners had achieved superior technical performance compared to free-hand learners. Furthermore, evolution in frontoparietal activation foci indicative of expertise was achieved at an earlier stage in practice amongst gaze-assisted learners. Both groups exhibited economical small world topology; however, networks in learners randomised to gaze-assistance were less costly and showed higher values of local efficiency suggesting improved frontoparietal communication in this group. We conclude that the benefits of gaze-assisted motor learning are evidenced by improved technical accuracy, more rapid task internalisation and greater neuronal efficiency. This form of assisted motor learning may have occupational relevance for high precision control such as in surgery or following re-learning as part of stroke rehabilitation.
authors.affiliation: Hamlyn Centre for Robotic Surgery, Imperial College London, UK.
authors.forename: David R C
authors.initials: DR
authors.lastname: James
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Leff
authors.forename: Felipe
authors.initials: F
authors.lastname: Orihuela-Espina
authors.forename: Ka-Wai
authors.initials: KW
authors.lastname: Kwok
authors.forename: George P
authors.initials: GP
authors.lastname: Mylonas
authors.forename: Thanos
authors.initials: T
authors.lastname: Athanasiou
authors.forename: Ara W
authors.initials: AW
authors.lastname: Darzi
authors.forename: Guang-Zhong
authors.initials: GZ
authors.lastname: Yang
mesh_terms: D000328:Adult; D001288:Attention / Q000502:physiology*; D005260:Female; D005403:Fixation, Ocular / Q000502:physiology*; D005625:Frontal Lobe / Q000502:physiology*; D006801:Humans; D007858:Learning / Q000502:physiology*; D008297:Male; D009048:Motor Skills / Q000502:physiology*; D009415:Nerve Net / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology; D010296:Parietal Lobe / Q000502:physiology*; D014836:Volition / Q000502:physiology