title: [Morphofunctional characteristics of rats' bone tissue after acute and subchronic emotional stress].
abstract: The investigation into the bone morphofunctional effects of acute and subchronic stress were performed in a series of two experiments with rats. In the first experiment, rats were subject to acute stress induced by confinement in plastic boxes for 1, 2.5 and 6 hours. In the other experiment, rats experienced subchronic stress from daily confinement for 5.5 hours during 3 and 9 days. Already after 2.5 hours in confinement the rats increased the number of trabecular osteoclasts and How-ship lacunas, as well as the blood level of free hydroxyproline. However, transformations of bone microarchitectonics, i.e. growth of trabecular breaks and sponger taper on femur X-ray pictures as an evidence of skeleton mechanic deterioration and relative femur mass reduction were found no earlier than after 9 days of stress
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000378:metabolism / Q000473:pathology*; D004195:Disease Models, Animal; D005269:Femur / Q000000981:diagnostic imaging / Q000473:pathology; D006909:Hydroxyproline / Q000097:blood; D010010:Osteoclasts / Q000378:metabolism*; D011859:Radiography; D051381:Rats; D013315:Stress, Psychological / Q000150:complications*; D013997:Time Factors
chemical_list: D006909:Hydroxyproline