title: Benefits and complications of the duodenal switch/biliopancreatic diversion compared to the Roux-en-Y gastric bypass.
abstract: BACKGROUND
  Despite providing superb excess weight loss and increased resolution of comorbid diseases, such as type 2 diabetes mellitus, compared to other bariatric procedures, the duodenal switch/ biliopancreatic diversion (DS/BD) has not gained widespread acceptance among patients and physicians. In this study, we investigated outcomes, symptoms and complications among postsurgical DS patients compared to RYGB patients.
  
  
  METHODS
  We used propensity scores to retrospectively match patients who underwent DS/BD between 2005 and 2010 to comparable Roux-en-Y gastric bypass (RYGB) patients. We then reviewed patient charts, and surveyed patients using the University of Minnesota Bariatric Surgery Outcomes Survey tool to track outcomes, comorbid illnesses and complications.
  
  
  RESULTS
  One hundred ninety consecutive patients underwent primary DS/BD between 2005 and 2010 at the University of Minnesota Medical Center. There were 178 patients available for follow-up (93.7%) who were matched to 139 RYGB patients. Type 2 diabetes, hypertension, and hyperlipidemia all significantly improved in each group. Improvements were significantly higher in the DS/BD group. Percent total weight loss was not different between groups. Loose stools and bloating symptoms were more frequently reported among DS/BD patients. With the exception of increased emergency department visits among DS/BD patients (P < .01), overall complication rates were not significantly different between DS/BD and RYGB. There was no difference in mortality rates between the groups.
  
  
  CONCLUSIONS
  The DS/BD is a robust procedure that engenders both superior weight loss and improvement of major comorbidities. Complication and adverse event rates are similar to those of RYGB.
authors.affiliation: Department of Surgery, University of Minnesota, Minneapolis, MN 55444, USA.
authors.forename: Robert B
authors.initials: RB
authors.lastname: Dorman
authors.forename: Nikolaus F
authors.initials: NF
authors.lastname: Rasmus
authors.forename: Benjamin J S
authors.initials: BJ
authors.lastname: al-Haddad
authors.forename: Federico J
authors.initials: FJ
authors.lastname: Serrot
authors.forename: Bridget M
authors.initials: BM
authors.lastname: Slusarek
authors.forename: Barbara K
authors.initials: BK
authors.lastname: Sampson
authors.forename: Henry
authors.initials: H
authors.lastname: Buchwald
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Leslie
authors.forename: Sayeed
authors.initials: S
authors.lastname: Ikramuddin
mesh_terms: D000328:Adult; D050110:Bariatric Surgery / Q000009:adverse effects* / Q000379:methods*; D015904:Biliopancreatic Diversion / Q000009:adverse effects*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D005260:Female; D015390:Gastric Bypass / Q000009:adverse effects*; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D006973:Hypertension / Q000150:complications; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology; D012189:Retrospective Studies; D016896:Treatment Outcome; D015431:Weight Loss