title: Ghrelin and eating disorders.
abstract: There is growing evidence supporting a multifactorial etiology that includes genetic, neurochemical, and physiological components for eating disorders above and beyond the more conventional theories based on psychological and sociocultural factors. Ghrelin is one of the key gut signals associated with appetite, and the only known circulating hormone that triggers a positive energy balance by stimulating food intake. This review summarizes recent findings and several conflicting reports on ghrelin in eating disorders. Understanding these findings and inconsistencies may help in developing new methods to prevent and treat patients with these disorders.
authors.affiliation: Department of Medicine, New York Obesity Research and Nutrition Center, St. Luke's-Roosevelt Hospital, New York, NY, USA. da2458@columbia.edu
authors.forename: Deniz
authors.initials: D
authors.lastname: Atalayer
authors.forename: Charlisa
authors.initials: C
authors.lastname: Gibson
authors.forename: Alexandra
authors.initials: A
authors.lastname: Konopacka
authors.forename: Allan
authors.initials: A
authors.lastname: Geliebter
mesh_terms: D001066:Appetite / Q000502:physiology; D004435:Eating / Q000502:physiology*; D004734:Energy Metabolism / Q000502:physiology; D001068:Feeding and Eating Disorders / Q000097:blood*; D054439:Ghrelin / Q000097:blood*; D006801:Humans
chemical_list: D054439:Ghrelin