title: Genomic advances for gene discovery in hereditary hearing loss.
abstract: High-throughput sequencing is changing the face of genetic diagnosis and counseling. While in the past, it would take on average 1 to 5 years to identify a mutation leading to deafness, today, the genetic basis for deafness can be determined within months in a child or adult with inherited hearing loss. Obstacles and challenges still remain, but the field is changing at a dramatic rate, making gene discovery a much easier and more efficient task than in the past.
authors.affiliation: Department of Human Molecular Genetics and Biochemistry, Tel Aviv University, Tel Aviv, Israel. karena@post.tau.ac.il
authors.forename: Karen B
authors.initials: KB
authors.lastname: Avraham
authors.forename: Moien
authors.initials: M
authors.lastname: Kanaan
mesh_terms: D003638:Deafness / Q000235:genetics*; D020022:Genetic Predisposition to Disease; D023281:Genomics; D006720:Homozygote; D006801:Humans