title: Organocatalytic oxidation of aldehydes to mixed anhydrides.
abstract: TEMPO catalyzes the direct oxidation of aldehydes to mixed anhydrides in the presence of a carboxylic acid. The anhydrides can be converted in situ to esters, secondary, tertiary or Weinreb amides in high yield. Oxidation of the aldehyde directly to 2-propyl esters is also possible using only catalytic amounts of acid. The oxidation reactions are rapid and take place under mild conditions.
authors.affiliation: Schulich Faculty of Chemistry, Technion-Israel Institute of Technology, 32000 Haifa, Israel.
authors.forename: Hila
authors.initials: H
authors.lastname: Toledo
authors.forename: Evgeni
authors.initials: E
authors.lastname: Pisarevsky
authors.forename: Adi
authors.initials: A
authors.lastname: Abramovich
authors.forename: Alex M
authors.initials: AM
authors.lastname: Szpilman