title: DNA mismatch repair: Dr. Jekyll and Mr. Hyde?
abstract: In this issue, Peña-Diaz et al. (2012) describe a pathway for somatic mutation in nonlymphoid cells termed noncanonical DNA mismatch repair, whereby the error-prone translesion polymerase Pol-η substitutes for high-fidelity replicative polymerases to resynthesize excised regions opposite DNA damage.
authors.affiliation: Genetics and Biochemistry Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health. peggyh@niddk.nih.gov
authors.forename: Peggy
authors.initials: P
authors.lastname: Hsieh