title: Febrile seizures and measles-mumps-rubella-varicella (MMRV) vaccine: what do primary care physicians think?
abstract: OBJECTIVE
  Measles-mumps-rubella-varicella (MMRV) vaccine is associated with increased febrile seizure risk compared with measles-mumps-rubella and varicella vaccine given separately (MMR+V) in children 12-15-month old. We assessed knowledge regarding MMRV and febrile seizures, intended practices, and factors influencing the decision to recommend MMRV.
  
  
  METHODS
  National survey administered 10/2008-1/2009 of US pediatricians (Peds) and family physicians (FP).
  
  
  RESULTS
  Response rate was 73% (620/849). Twenty-nine percent of Peds and 74% of FP (p<0.001) were unaware of increased febrile seizure risk after MMRV. After reading an informational statement, 20% of Peds and 7% of FP (p<0.001) would recommend MMRV to a healthy 12-15-month-old child. The factor most frequently reported as "very important" in the decision to recommend MMRV or MMR+V was ACIP/AAFP/AAP recommendations (pediatricians, 77%, family physicians, 73%, p=0.08).
  
  
  CONCLUSIONS
  After receiving data regarding febrile seizure risk after MMRV, few physicians report they would recommend MMRV to a healthy 12-15-month-old child.
authors.affiliation: Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. sean.o'leary@childrenscolorado.org
authors.forename: Sean T
authors.initials: ST
authors.lastname: O'Leary
authors.forename: Christina A
authors.initials: CA
authors.lastname: Suh
authors.forename: Mona
authors.initials: M
authors.lastname: Marin
mesh_terms: D019433:Chickenpox Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007223:Infant; D022542:Measles-Mumps-Rubella Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D058007:Physicians, Primary Care; D003294:Seizures, Febrile / Q000139:chemically induced*; D011795:Surveys and Questionnaires; D014611:Vaccination / Q000379:methods* / Q000706:statistics & numerical data; D017778:Vaccines, Combined / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D019433:Chickenpox Vaccine; D022542:Measles-Mumps-Rubella Vaccine; D017778:Vaccines, Combined; C050102:measles, mumps, rubella, varicella vaccine