title: [Long-term outcome of CO₂ laser microlaryngoscopic treatment for laryngeal cancer].
abstract: OBJECTIVE
  To investigate the long-term outcome of CO₂ laser microsurgery for laryngeal cancer.
  
  
  METHODS
  Seventy patients with laryngeal cancer were treated with CO₂ laser microsurgery. All patients were followed up for at least 36 months (36 - 108 months).
  
  
  RESULTS
  During the 36-108 months follow-up, 64 patients were alive, and 6 patients died of recurrence. The total 5-year survival rate was 91.4%, 5-year local control rate was 81.4%, 5-year local recurrence rate was 18.6%, and the neck metastasis rate was 4.3%. All survivals had normal breathing and good phonation.
  
  
  CONCLUSIONS
  The long-term outcomes of CO₂ laser microsurgery for laryngeal cancer are good, with rapid recovery and few complications, well protected laryngeal function and quite good quality of life. Laser surgery should be the priority of treatment for early stage laryngeal cancer. However, laser surgery for advanced laryngeal cancers and supraglottic laryngeal cancers should be carefully chosen.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Guangdong General Hospital and Guangdong Academy of Medical Sciences, Guangzhou 510080, China.
authors.forename: Zhong-ming
authors.initials: ZM
authors.lastname: Lu
authors.forename: Xin-han
authors.initials: XH
authors.lastname: Song
authors.forename: Si-yi
authors.initials: SY
authors.lastname: Zhang
authors.forename: Hong-bin
authors.initials: HB
authors.lastname: Zhang
authors.forename: Liang-si
authors.initials: LS
authors.lastname: Chen
authors.forename: Xiao-ning
authors.initials: XN
authors.lastname: Luo
authors.forename: Shao-hua
authors.initials: SH
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D054020:Lasers, Gas / Q000627:therapeutic use*; D008207:Lymphatic Metastasis; D008297:Male; D008866:Microsurgery / Q000379:methods; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011788:Quality of Life; D020127:Recovery of Function; D015996:Survival Rate; D016896:Treatment Outcome