title: Tandem synthesis of highly functionalized pyrazole derivatives from terminal alkynes, sulfonyl azides, diethyl azadicarboxylate, and sodium arylsulfinates.
abstract: The reaction between ketenimine intermediates [generated from terminal alkynes and sulfonyl azides], diethyl azadicarboxylate, and sodium arylsulfinates in N, N-dimethylformamide at room temperature, affords ethyl 2,3-dihydro-3-oxo-4-phenyl-2-tosyl-5-(tosylamino)pyrazole-1-carboxylates in moderate-to-good yields. When diisopropyl azadicarboxylate was used as the ester component, diisopropyl 1-arylsulfonyl-2-{[aryl(alkyl)sulfonyl]-2-phenylethanimidoyl}-1,2-hydrazinedicarboxylates were obtained.
authors.affiliation: Department of Chemistry, Tarbiat Modares University, Tehran, Iran. yavarisa@modares.ac.ir
authors.forename: Issa
authors.initials: I
authors.lastname: Yavari
authors.forename: Manijeh
authors.initials: M
authors.lastname: Nematpour
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D011720:Pyrazoles / Q000138:chemical synthesis*; D013438:Sulfhydryl Compounds / Q000737:chemistry*; D013452:Sulfonium Compounds / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001386:Azides; D011720:Pyrazoles; D013438:Sulfhydryl Compounds; D013452:Sulfonium Compounds