title: Correlation of surgical pleth index with stress hormones during propofol-remifentanil anaesthesia.
abstract: Eighty patients undergoing elective ear-nose-throat surgery were enrolled in the present study to investigate the relationship between surgical pleth index (SPI) and stress hormones (ACTH, cortisol, epinephrine, norepinephrine) during general anaesthesia which was induced and maintained with propofol and remifentanil using a target-controlled infusion. The study concluded that the SPI had moderate correlation to the stress hormones during general anaesthesia, but no correlation during consciousness. Furthermore, SPI values were able to predict ACTH values with high sensitivity and specificity.
authors.affiliation: Department of Anaesthesia, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310058, China. chenxinz@zju.edu.cn
authors.forename: Xinzhong
authors.initials: X
authors.lastname: Chen
authors.forename: Carsten
authors.initials: C
authors.lastname: Thee
authors.forename: Matthias
authors.initials: M
authors.lastname: Gruenewald
authors.forename: Christoph
authors.initials: C
authors.lastname: Ilies
authors.forename: Jan
authors.initials: J
authors.lastname: Höcker
authors.forename: Robert
authors.initials: R
authors.lastname: Hanss
authors.forename: Markus
authors.initials: M
authors.lastname: Steinfath
authors.forename: Berthold
authors.initials: B
authors.lastname: Bein
mesh_terms: D000293:Adolescent; D000324:Adrenocorticotropic Hormone / Q000097:blood*; D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D062186:Arterial Pressure; D001919:Bradycardia / Q000473:pathology; D003243:Consciousness; D004837:Epinephrine / Q000097:blood*; D005260:Female; D006339:Heart Rate; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood; D010038:Otorhinolaryngologic Diseases / Q000601:surgery; D010880:Piperidines / Q000008:administration & dosage*; D015742:Propofol / Q000008:administration & dosage*; D011446:Prospective Studies; D012372:ROC Curve; D012016:Reference Values; D000077208:Remifentanil; D012680:Sensitivity and Specificity; D016037:Single-Blind Method; D013223:Statistics as Topic / Q000379:methods; D018709:Statistics, Nonparametric; D013312:Stress, Physiological; D055815:Young Adult
chemical_list: D018686:Anesthetics, Intravenous; D010880:Piperidines; D000324:Adrenocorticotropic Hormone; D000077208:Remifentanil; D006854:Hydrocortisone; D009638:Norepinephrine; D015742:Propofol; D004837:Epinephrine