title: Capillary electrophoresis for the detection of Fragile X expanded alleles.
abstract: Capillary electrophoresis is an analytical technique that separates ions based on their electrophoresis mobility with the use of an applied voltage. Capillary electrophoresis is used most predominantly in nuclear acid fragment analysis as well as DNA sequencing because it gives faster results and provides high resolution separation. Here we describe an application using capillary electrophoreses for screening the Fragile X expanded alleles to demonstrate the application.
authors.affiliation: Pathology Department, University of Utah School of Medicine, Salt Lake City, UT, USA. rong.mao@aruplab.com
authors.forename: Rong
authors.initials: R
authors.lastname: Mao
authors.forename: Pinar
authors.initials: P
authors.lastname: Bayrak-Toydemir
authors.forename: Elaine
authors.initials: E
authors.lastname: Lyon
mesh_terms: D000483:Alleles; D001483:Base Sequence; D004247:DNA / Q000302:isolation & purification; D003627:Data Interpretation, Statistical; D019075:Electrophoresis, Capillary / Q000295:instrumentation / Q000379:methods*; D005600:Fragile X Syndrome / Q000175:diagnosis* / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012984:Software; D013223:Statistics as Topic; D019680:Trinucleotide Repeat Expansion / Q000235:genetics*
chemical_list: D004247:DNA