title: A new activity of N-cholinolytic drug benzohexonium.
abstract: We have found that N-cholinolytic drug benzohexonium produces a hypolipidemic effect: it reduces dyslipoproteinemia, fatty infiltration of the liver, and risk of atherosclerotic lesions.
authors.affiliation: Institute of Experimental Medicine, North-Western Division of the Russian Academy of Medical Sciences, St. Petersburg, Russia. Ludmila.Konst83@ mail.ru
authors.forename: L K
authors.initials: LK
authors.lastname: Khnychenko
authors.forename: I V
authors.initials: IV
authors.lastname: Okunevich
authors.forename: N A
authors.initials: NA
authors.lastname: Losev
authors.forename: N S
authors.initials: NS
authors.lastname: Sapronov
authors.forename: E E
authors.initials: EE
authors.lastname: Yakovleva
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D018680:Cholinergic Antagonists / Q000494:pharmacology* / Q000627:therapeutic use; D004195:Disease Models, Animal; D050171:Dyslipidemias / Q000188:drug therapy*; D005234:Fatty Liver / Q000188:drug therapy*; D006168:Guinea Pigs; D006584:Hexamethonium Compounds / Q000494:pharmacology* / Q000627:therapeutic use; D000960:Hypolipidemic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D050356:Lipid Metabolism / Q000187:drug effects; D008297:Male; D058226:Plaque, Atherosclerotic / Q000517:prevention & control*; D051381:Rats
chemical_list: D018680:Cholinergic Antagonists; D006584:Hexamethonium Compounds; D000960:Hypolipidemic Agents; C021628:benzohexonium