title: Study on the interaction between gelatin and polyurethanes derived from fatty acids.
abstract: In this study, gelatin was blended to proprietary noncytotoxic polyurethanes (PU) derived from vegetable oils with different weight ratios, as material for the preparation of novel biomedical products. The PU/gelatin blends were characterized for their morphology through scanning electron microscopy. Mechanical and thermal properties, chemical interactions between components, degradation behavior, surface properties, cell adhesion, and bioactivity were investigated as a function of the protein content. Higher blend miscibility was observed for the amorphous PUs, derived from oleic acid. Properties of PU/gelatin films were strongly influenced by the concentration of gelatin in the films. Gelatin enhanced the hydrophilicity, bioactivity, and cell adhesion of PUs.
authors.affiliation: Department of Analytical and Organic Chemistry, Rovira i Virgili University, Tarragona 43007, Spain.
authors.forename: R J
authors.initials: RJ
authors.lastname: González-Paz
authors.forename: G
authors.initials: G
authors.lastname: Lligadas
authors.forename: J C
authors.initials: JC
authors.lastname: Ronda
authors.forename: M
authors.initials: M
authors.lastname: Galià
authors.forename: A M
authors.initials: AM
authors.lastname: Ferreira
authors.forename: F
authors.initials: F
authors.lastname: Boccafoschi
authors.forename: G
authors.initials: G
authors.lastname: Ciardelli
authors.forename: V
authors.initials: V
authors.lastname: Cádiz
mesh_terms: D000818:Animals; D002417:Cattle; D002448:Cell Adhesion; D005780:Gelatin / Q000737:chemistry*; D008422:Materials Testing; D008567:Membranes, Artificial; D051379:Mice; D041681:NIH 3T3 Cells; D019301:Oleic Acid / Q000737:chemistry*; D010938:Plant Oils / Q000737:chemistry*; D011140:Polyurethanes / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D008567:Membranes, Artificial; D010938:Plant Oils; D011140:Polyurethanes; D019301:Oleic Acid; D005780:Gelatin