title: A novel and simple strategy for simultaneous determination of dopamine, uric acid and ascorbic acid based on the stacked graphene platelet nanofibers/ionic liquids/chitosan modified electrode.
abstract: A promising electrochemical sensor for simultaneous determination of dopamine (DA), uric acid (UA) and ascorbic acid (AA) was fabricated based on the stacked graphene platelet nanofibers (SGNF)/ionic liquid (IL)/chitosan (CS) modified electrode. The SGNF/IL/CS modified electrode possessed excellent electrocatalytic activity towards the oxidation of DA, UA and AA with obvious reduction of over-potential and increased peak current, and the separations of oxidation peak potentials of DA-UA, DA-AA, and UA-AA were of 151, 213 and 364 mV, respectively. Under the optimum conditions, the linear range for the detection of DA, UA and AA were 0.05-240, 0.12-260, and 30-350 μM with the lowest detection limits of 0.05, 0.10 and 14.8 μM for DA, UA and AA, respectively. In addition, the electrochemical sensor showed high sensitivity, excellent selectivity, reproducibility and long-term stability.
authors.affiliation: College of Chemistry and Chemical Engineering, Key Lab of Bioelectrochemistry and Environmental Analysis of Gansu Province, Northwest Normal University, Lanzhou 730070, PR China.
authors.forename: Xiuli
authors.initials: X
authors.lastname: Niu
authors.forename: Wu
authors.initials: W
authors.lastname: Yang
authors.forename: Hao
authors.initials: H
authors.lastname: Guo
authors.forename: Jie
authors.initials: J
authors.lastname: Ren
authors.forename: Fusheng
authors.initials: F
authors.lastname: Yang
authors.forename: Jinzhang
authors.initials: J
authors.lastname: Gao
mesh_terms: D001205:Ascorbic Acid / Q000032:analysis* / Q000737:chemistry / Q000652:urine; D048271:Chitosan / Q000737:chemistry*; D004298:Dopamine / Q000032:analysis* / Q000737:chemistry / Q000652:urine; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods*; D004566:Electrodes; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D052578:Ionic Liquids / Q000737:chemistry*; D057230:Limit of Detection; D057139:Nanofibers / Q000737:chemistry; D010084:Oxidation-Reduction; D015203:Reproducibility of Results; D013997:Time Factors; D014527:Uric Acid / Q000032:analysis* / Q000737:chemistry / Q000652:urine
chemical_list: D052578:Ionic Liquids; D014527:Uric Acid; D006108:Graphite; D048271:Chitosan; D001205:Ascorbic Acid; D004298:Dopamine