title: Anterior cervical discectomy and fusion for the management of axial neck pain in the absence of radiculopathy or myelopathy.
abstract: METHODS
  Systematic reviewStudy rationale: Anterior cervical discectomy and fusion (ACDF) is a proven, effective treatment for relieving neck pain due to degenerative conditions of the cervical spine. Since most patients also present with radiculopathy or myelopathy, little is known as to the effectiveness of ACDF to relieve pain and improve function in patients without radicular or myelopathic symptoms.
  
  
  OBJECTIVE
  To examine the clinical outcome in patients undergoing (ACDF) for axial neck pain without radicular or myelopathic symptoms.
  
  
  METHODS
  A systematic review was undertaken for articles published up to March 2010. Electronic databases and reference lists of key articles were searched to identify studies evaluating ACDF for the treatment of axial neck pain only. Radiculopathy and myelopathy, patients who suffered severe trauma, or with tumor/metastatic disease or infection were excluded. Two independent reviewers assessed the strength of evidence using the grading of recommendations assessment, development and evaluation (GRADE) system, and disagreements were resolved by consensus.
  
  
  RESULTS
  No comparative studies were identified. Three case series met our inclusion criteria and were evaluated. All studies showed a mean improvement of pain of at least 50% approximately 4-years following surgery. Functional outcomes improved between 32% and 52% from baseline. Most patients reported satisfaction with surgery, 56% in one study and 79% in another. Complications varied among studies ranging from 1% to 10% and included pseudoarthrosis (9%), nonunion and revision (3%) and screw removal (1%).
  
  
  CONCLUSIONS
  There is low evidence suggesting that patients with axial neck pain without radicular or myelopathic symptoms may receive some improvement in pain and function following ACDF. However, whether this benefit is greater than nontreatment or other treatments cannot be determined with the present literature.
authors.affiliation: Washington University Orthopaedics, Barnes-Jewish Hospital, St. Louis, MO, USA.
authors.forename: K Daniel
authors.initials: KD
authors.lastname: Riew
authors.forename: Erika
authors.initials: E
authors.lastname: Ecker
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Dettori