title: Austrian syndrome in the context of a fulminant pneumococcal native valve endocarditis.
abstract: This is the case of a young male suffering from Austrian syndrome, which is the triad of endocarditis, meningitis, and pneumonia due to invasive S. pneumoniae infection. He reported recurrent fever for six months without any antibiotic treatment, which may have determined the further course of the syndrome. Echocardiography revealed massive native valve endocarditis, and the patient was considered for ultima-ratio cardiac surgery. Intraoperative aspect presented extensive affection of the aortic root with full destruction of aortic valve, mitral valve, and aortomitral continuity. The myocardium showed a phlegmon-like infiltration. Microbiologic testing of intraoperatively collected specimens identified penicillin-sensitive Streptococcus pneumoniae. S. pneumoniae is a very uncommon cause for infective infiltrative endocarditis and is associated with severe clinical courses. Austrian syndrome is even more rare, with only a few reported cases worldwide. In those patients, only early diagnosis, immediate antibiotic treatment, and emergent cardiac surgery can save lives.
authors.affiliation: Heart Center Dresden, Department of Cardiac Surgery, Technical University of Dresden, Germany. manuel.wilbring@gmail.com
authors.forename: Manuel
authors.initials: M
authors.lastname: Wilbring
authors.forename: Sems-Malte
authors.initials: SM
authors.lastname: Tugtekin
authors.forename: Klaus
authors.initials: K
authors.lastname: Matschke
authors.forename: Utz
authors.initials: U
authors.lastname: Kappert
mesh_terms: D000328:Adult; D001021:Aortic Valve; D004697:Endocarditis, Bacterial / Q000175:diagnosis* / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008586:Meningitis, Pneumococcal / Q000175:diagnosis*; D008943:Mitral Valve; D011018:Pneumonia, Pneumococcal / Q000175:diagnosis*; D013290:Streptococcal Infections / Q000175:diagnosis*; D013577:Syndrome