title: Oral delivery of anticancer drugs III: formulation using drug delivery systems.
abstract: In the past few years, the growth of nanometric size drug delivery systems (DDS) has burst into challenging innovations enabling real progresses to achieve oral delivery of anticancer drugs. DDS, such as polymeric nanoparticles, micelles, dendrimers and lipid-based formulations enable physico-chemical properties of cytotoxic agents to be improved and oral bioavailability to be enhanced. In this review we highlight current DDS used for the oral delivery of anticancer drugs.
authors.affiliation: Université Paris-Sud, Faculté de Pharmacie, UMR CNRS 8612, Institut Galien Paris-Sud, 5, rue JB Clément, 92296 Châtenay-Malabry Cedex, France.
authors.forename: Silvia
authors.initials: S
authors.lastname: Mazzaferro
authors.forename: Kawthar
authors.initials: K
authors.lastname: Bouchemal
authors.forename: Gilles
authors.initials: G
authors.lastname: Ponchel
mesh_terms: D000284:Administration, Oral; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000627:therapeutic use; D001682:Biological Availability; D050091:Dendrimers / Q000737:chemistry; D016503:Drug Delivery Systems; D015195:Drug Design; D006801:Humans; D008055:Lipids / Q000737:chemistry; D008823:Micelles; D053758:Nanoparticles; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology; D011108:Polymers / Q000737:chemistry
chemical_list: D000970:Antineoplastic Agents; D050091:Dendrimers; D008055:Lipids; D008823:Micelles; D011108:Polymers