title: Engineering glucosinolates in plants: current knowledge and potential uses.
abstract: Glucosinolates (GSL) and their derivatives are well known for the characteristic roles they play in plant defense as signaling molecules and as bioactive compounds for human health. More than 130 GSLs have been reported so far, and most of them belong to the Brassicaceae family. Several enzymes and transcription factors involved in the GSL biosynthesis have been studied in the model plant, Arabidopsis, and in a few other Brassica crop species. Recent studies in GSL research have defined the regulation, distribution, and degradation of GSL biosynthetic pathways; however, the underlying mechanism behind transportation of GSLs in plants is still largely unknown. This review highlights the recent advances in the metabolic engineering of GSLs in plants and discusses their potential applications.
authors.affiliation: Department of Molecular Biotechnology, School of Life & Environmental Sciences, Konkuk University, Seoul 143701, South Korea.
authors.forename: Venkidasamy
authors.initials: V
authors.lastname: Baskar
authors.forename: Mayank Anand
authors.initials: MA
authors.lastname: Gururani
authors.forename: Jae Woong
authors.initials: JW
authors.lastname: Yu
authors.forename: Se Won
authors.initials: SW
authors.lastname: Park
mesh_terms: D053898:Biosynthetic Pathways; D005961:Glucosinolates / Q000096:biosynthesis*; D060847:Metabolic Engineering / Q000639:trends*; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism; D010944:Plants / Q000235:genetics* / Q000378:metabolism*
chemical_list: D005961:Glucosinolates; D010940:Plant Proteins