title: Preoperative anaemia is common in patients undergoing major gynaecological surgery and is associated with a fivefold increased risk of transfusion.
abstract: OBJECTIVE
  To ascertain the incidence of preoperative anaemia in a cohort of patients undergoing major gynaecological surgery in a tertiary Australian hospital over a two-year period and to investigate whether it is associated with an increased rate of transfusion or complications.
  
  
  METHODS
  Using the Western Australian Patient Blood Management (PBM) Data System, we obtained data for 843 women undergoing major gynaecological surgery over a two-year period at King Edward Memorial Hospital, Subiaco, Western Australia. We used regression analysis to investigate the relationship between preoperative anaemia, red cell transfusion, length of hospital stay and complications.
  
  
  RESULTS
  Preoperative anaemia was present in 18.1% of women and was associated with a significantly increased risk of receiving a red cell transfusion (OR = 5.74, P < 0.001). After adjusting for confounders, preoperative anaemia was not independently associated with increased complications or hospital length of stay, but receiving a red cell transfusion was (P < 0.001).
  
  
  CONCLUSIONS
  This study demonstrates preoperative anaemia is common in women undergoing elective major gynaecological surgery and is associated with increased red cell transfusions. A system to detect and treat anaemia prior to surgery in these patients should be implemented, and interventions should be evaluated to ensure they are effective.
authors.affiliation: Department Anaesthesia and Pain Medicine, King Edward Memorial Hospital, Subiaco, WA, Australia. roger.browning@health.wa.gov.au
authors.forename: Roger M
authors.initials: RM
authors.lastname: Browning
authors.forename: Kevin
authors.initials: K
authors.lastname: Trentino
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Nathan
authors.forename: Navid
authors.initials: N
authors.lastname: Hashemi
mesh_terms: D000368:Aged; D000740:Anemia / Q000097:blood / Q000453:epidemiology*; D016001:Confidence Intervals; D017707:Erythrocyte Transfusion; D005260:Female; D013509:Gynecologic Surgical Procedures; D006801:Humans; D015994:Incidence; D007902:Length of Stay; D016015:Logistic Models; D008875:Middle Aged; D016017:Odds Ratio; D011183:Postoperative Complications / Q000453:epidemiology*; D057234:Preoperative Period; D012307:Risk Factors