title: Optometry-based general population survey of pupil ruff atrophy and ocular hypertension.
abstract: BACKGROUND
  To evaluate and describe the pupil ruff changes and relationship to intraocular pressure, pseudoexfoliation syndrome and glaucoma status in an optometric population in New Zealand.
  
  
  METHODS
  Prospective cross-sectional survey of an optometric population.
  
  
  METHODS
  Six hundred and twenty subjects over 50 years old routinely attending the participating optometry practices. Exclusion criteria included previous intraocular surgery, ophthalmic laser, uveitis, angle closure and secondary glaucoma.
  
  
  METHODS
  Multicentre study involving 11 optometry practices in the Wellington region, New Zealand. The pupillary ruff and associated gonioscopy findings of study participants were graded based on the previously published Pupil Ruff Atrophy grading system. Parameters evaluated include pupillary ruff absence and abnormality, pseudoexfoliation material and trabecular meshwork pigmentation.
  
  
  METHODS
  Correlations between intereye Pupil Ruff Atrophy grading differences and inter-eye intraocular pressure and cup:disc ratio differences.
  
  
  RESULTS
  Six hundred and twenty subjects were included, with a mean age of 62.2 ± 9.1 years and mean intraocular pressure of 14.8 ± 3.4 mmHg. Four hundred and fourteen (66.8%) had bilateral pupil ruff changes and 12 (1.5%) had pseudoexfoliation. Inter-eye intraocular pressure asymmetry was significantly correlated with amount of missing pupillary ruff (r = 0.111; P = 0.022) and trabecular meshwork pigmentation (r = 0.147; P = 0.002). Inter-eye cup:disc ratio asymmetry was not correlated with any of the Pupil Ruff Atrophy grading parameters.
  
  
  CONCLUSIONS
  Asymmetry of pupillary ruff absence and trabecular meshwork pigmentation was correlated with intraocular pressure asymmetry (but not with cup:disc ratio asymmetry) in a general optometric population setting in New Zealand.
authors.affiliation: Capital Eye Specialists, Wellington Hospital, Wellington, New Zealand.
authors.forename: Ghee S
authors.initials: GS
authors.lastname: Ang
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Stevenson
authors.forename: Geoff
authors.initials: G
authors.lastname: Sargent
authors.forename: Peter
authors.initials: P
authors.lastname: Grimmer
authors.forename: Patricia
authors.initials: P
authors.lastname: Corbett
authors.forename: Erin
authors.initials: E
authors.lastname: Jourdain
authors.forename: Anthony P
authors.initials: AP
authors.lastname: Wells
mesh_terms: D001284:Atrophy / Q000145:classification; D003430:Cross-Sectional Studies; D017889:Exfoliation Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006068:Gonioscopy; D006306:Health Surveys; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D007498:Iris / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis* / Q000503:physiopathology; D009907:Optometry; D011446:Prospective Studies; D011680:Pupil; D014065:Tonometry, Ocular; D014129:Trabecular Meshwork / Q000473:pathology*