title: Novel NSP4 genotype in a camel G10P[15] rotavirus strain.
abstract: In this study a Kuwaiti camel rotavirus strain, RVA/Camel-wt/KUW/s21/2010/G10P[15], is characterized by sequencing and phylogenetic analysis. The strain had multiple genes with high nucleotide sequence similarities to ovine and bovine strains (VP2, ≤ 96%; NSP2 and NSP5, ≤ 97%, NSP3, ≤ 94%), or, to porcine strains (VP1, ≤ 89%). Other genes had moderate sequence similarities (VP4, ≤ 87%; VP6, ≤ 81%; VP7, ≤ 82%) with reference strains from ruminants. The NSP4 gene shared limited sequence identity (≤ 71%) with other mammalian and avian rotavirus NSP4 types, and was designated a novel genotype, E15. This study demonstrates genetic diversity in the outer capsid and some backbone genes of an old-world camelid rotavirus strain and uncovers its common evolutionary roots with strains from other ruminants.
authors.affiliation: Hungarian Academy of Sciences, Institute for Veterinary Medical Research, Budapest, Hungary.
authors.forename: Hajnalka
authors.initials: H
authors.lastname: Papp
authors.forename: Laila Zaar
authors.initials: LZ
authors.lastname: Al-Mutairi
authors.forename: Wassim
authors.initials: W
authors.lastname: Chehadeh
authors.forename: Szilvia L
authors.initials: SL
authors.lastname: Farkas
authors.forename: György
authors.initials: G
authors.lastname: Lengyel
authors.forename: Ferenc
authors.initials: F
authors.lastname: Jakab
authors.forename: Vito
authors.initials: V
authors.lastname: Martella
authors.forename: György
authors.initials: G
authors.lastname: Szűcs
authors.forename: Krisztián
authors.initials: K
authors.lastname: Bányai
mesh_terms: D000818:Animals; D002162:Camelus / Q000382:microbiology*; D002417:Cattle; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D010802:Phylogeny; D012401:Rotavirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000382:microbiology* / Q000662:veterinary*; D012756:Sheep; D013552:Swine; D017361:Viral Nonstructural Proteins / Q000235:genetics*
chemical_list: D017361:Viral Nonstructural Proteins