title: Evaluation of a new approach to the treatment of lymphedema resulting from breast cancer therapy.
abstract: OBJECTIVE
  The aim of this study was to evaluate a new form of intensive treatment for arm lymphedema.
  
  
  METHODS
  A prospective study of 66 patients with breast cancer-related lymphedema was performed. The ages of the patients ranged from 35 to 83 years old with a mean of 58.8 years. Diagnosis of lymphedema was made by physical examination and water-displacement volumetry (a difference of ≥ 200 mL between arms). All the patients were submitted to clinical treatment in an outpatient setting which involved a once-weekly session of 3 to 4h of manual and mechanical lymph drainage, myolymphokinetic activities and exercising using facilitating apparatuses and the use of a medical compression sleeve. Monthly volumetry evaluations were routinely performed. The Student t-test was employed for statistical analysis with an alpha level of 5% (p<0.05) being considered significant.
  
  
  RESULTS
  The mean follow-up time between cancer treatment and this study was 12.3 months. A significant reduction in the size of the arms was observed for all patients. The mean difference between the lymphedematous and normal arms of all patients was 553.8 mL at the start of treatment and a mean reduction of 70.1% (388.7 mL) of the edema was achieved (p=0.0001).
  
  
  CONCLUSIONS
  In our experience, this model of treatment appeared efficacious in decreasing and maintaining the reduction in volume of arm in breast cancer-related lymphedema.
authors.affiliation: University Medical of São Jose do Rio Preto-FAMERP-Brazil Cardiology and Vascular Surgery Rua Floriano Peixoto São Jose do Rio Preto, Brazil. godoyjmp@riopreto.com.br
authors.forename: José Maria Pereira
authors.initials: JM
authors.lastname: de Godoy
authors.forename: Maria de Fatima Guerreiro
authors.initials: Mde F
authors.lastname: Godoy
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001132:Arm; D001943:Breast Neoplasms / Q000628:therapy; D003131:Combined Modality Therapy; D004322:Drainage; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D008209:Lymphedema / Q000209:etiology / Q000628:therapy*; D008875:Middle Aged; D011446:Prospective Studies