title: Potential of placenta-derived mesenchymal stem cells as seed cells for bone tissue engineering: preliminary study of osteoblastic differentiation and immunogenicity.
abstract: Mesenchymal stem cells (MSCs) have been isolated from a variety of human tissues (eg, bone marrow, peripheral blood, muscle, fat, umbilical blood, amniotic fluid, embryonic tissues, and placenta). Placenta-derived MSCs (PDMSCs) have received considerable interest because of their wide availability and absence of ethical concerns. The authors characterized the biological properties, ultrastructure, growth factor production, and osteoblastic differentiation of PDMSCs and investigated their potential as seed cells for bone tissue engineering.
authors.affiliation: Department of Orthopedics, First Hospital of Shaoguan, Guangdong Medical College, Guangdong, China.
authors.forename: Zhi-Nian
authors.initials: ZN
authors.lastname: Zhong
authors.forename: Shao-Fang
authors.initials: SF
authors.lastname: Zhu
authors.forename: Ai-Dong
authors.initials: AD
authors.lastname: Yuan
authors.forename: Guo-Hui
authors.initials: GH
authors.lastname: Lu
authors.forename: Zheng-Yan
authors.initials: ZY
authors.lastname: He
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Fa
authors.forename: Wen-Hu
authors.initials: WH
authors.lastname: Li
mesh_terms: D061249:Batch Cell Culture Techniques / Q000379:methods; D002454:Cell Differentiation / Q000276:immunology; D049109:Cell Proliferation; D002478:Cells, Cultured; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology* / Q000276:immunology*; D010006:Osteoblasts / Q000166:cytology* / Q000276:immunology*; D010012:Osteogenesis / Q000276:immunology*; D010865:Pilot Projects; D010920:Placenta; D011247:Pregnancy; D023822:Tissue Engineering / Q000379:methods*