title: High 18F-fluorothymidine uptake for invasive thymoma.
abstract: We report an invasive thymoma discovered incidentally by an 18F-FLT (fluorothymidine) PET study on a 48-year-old woman. The patient had equivocal breast lesions in her bilateral breasts. She entered a clinical 18F-FLT PET trial in our hospital to differentiate malignant breast tumors from benign ones. No 18F FLT-avid lesions in her breasts were revealed. But an intense 18F-FLT uptake lesion was noted in her right anterior mediastinum. However, an F-FDG PET scan showed only mild F-FDG uptake in the lesion. Video-assisted thoracic surgery thymectomy was subsequently performed, and the final pathology showed invasive thymoma.
authors.affiliation: Department of Nuclear Medicine, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Chia-Ju
authors.initials: CJ
authors.lastname: Liu
authors.forename: Jane
authors.initials: J
authors.lastname: Wang
authors.forename: Wen-Hung
authors.initials: WH
authors.lastname: Kuo
authors.forename: Ruoh-Fang
authors.initials: RF
authors.lastname: Yen
mesh_terms: D001692:Biological Transport; D015224:Dideoxynucleosides / Q000378:metabolism*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D049268:Positron-Emission Tomography; D013945:Thymoma / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology*; D013953:Thymus Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology*
chemical_list: D015224:Dideoxynucleosides; C002854:alovudine