title: Evaluation of safe infusion devices for antineoplastic administration.
abstract: Nurses endure daily low-level exposure to cytotoxic drugs, which can lead to significant absorption with potential harmful consequences. New sterile medical devices called cytotoxic safe infusion systems (CSISs), intended by their manufacturers to improve safety and quality of cytotoxic drug infusions, have been made commercially available. CSISs from 3 manufacturers were tested in 2 cancer units and compared with standard infusion sets. The aim of this study is to evaluate the devices regarding occupational exposure, quality of the infusion, and economic aspects.
authors.affiliation: Department of Pharmacy, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France. laure.lalande@chu-lyon.fr
authors.forename: Laure
authors.initials: L
authors.lastname: Lalande
authors.forename: Guillaume
authors.initials: G
authors.lastname: Galy
authors.forename: Emilie
authors.initials: E
authors.lastname: Dussossoy
authors.forename: Jean-Etienne
authors.initials: JE
authors.lastname: Noyel
authors.forename: Christine
authors.initials: C
authors.lastname: Pivot
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D003603:Cytotoxins; D006801:Humans; D007262:Infusions, Intravenous / Q000009:adverse effects / Q000379:methods / Q000451:nursing*; D016273:Occupational Exposure / Q000517:prevention & control; D009859:Oncology Nursing / Q000379:methods*; D010818:Practice Patterns, Physicians'; D018570:Risk Assessment
chemical_list: D000970:Antineoplastic Agents; D003603:Cytotoxins