title: The late recurrence of ganglioneuroma 21 years after initial presentation with neuroblastoma.
abstract: A 3-year-old boy presented with tumors in the adrenal gland and the right orbit, and was diagnosed with neuroblastoma. After chemotherapy, the tumors were resected and the pathological diagnoses of ganglioneuroblastoma in the adrenal gland and ganglioneuroma in the orbit were made. The tumor relapsed at the intracranial dura mater 21 years after the initial diagnosis, and was diagnosed as ganglioneuroma from a biopsied sample. This case is very unique in that ganglioneuroma matured from ganglioneuroblastoma or neuroblastoma had the late recurrence with 21 years of tumor dormancy.
authors.affiliation: Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan.
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Okita
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Narita
authors.forename: Akihiko
authors.initials: A
authors.lastname: Yoshida
authors.forename: Yasuji
authors.initials: Y
authors.lastname: Miyakita
authors.forename: Makoto
authors.initials: M
authors.lastname: Ohno
authors.forename: Masanao
authors.initials: M
authors.lastname: Saio
authors.forename: Naoki
authors.initials: N
authors.lastname: Yoshimi
authors.forename: Soichiro
authors.initials: S
authors.lastname: Shibui
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002675:Child, Preschool; D018450:Disease Progression; D018305:Ganglioneuroblastoma / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D005729:Ganglioneuroma / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009447:Neuroblastoma / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D012008:Recurrence