title: Reaction of glycal derivatives with alcohols in the presence of N-bromosuccinimide and diphenyldiselenide: preparation of 2-deoxy-2-phenylselenyl glycosides.
abstract: Reaction of glycal derivatives with alcohols or glycosyl acceptors in the presence of N-bromosuccinimide (NBS) and diphenyldiselenide resulted in the formation of alkyl 2-deoxy-2-phenylselenyl glycosides or disaccharide derivatives in excellent yield. The reactions are reasonably fast and considerable stereo-selectivity was observed in the preparation of disaccharide derivatives.
authors.affiliation: Bose Institute, Division of Molecular Medicine, P-1/12, CIT Scheme VII-M, Kolkata 700054, India.
authors.forename: Abhijit
authors.initials: A
authors.lastname: Sau
authors.forename: Anup Kumar
authors.initials: AK
authors.lastname: Misra
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D001555:Benzene Derivatives / Q000737:chemistry*; D001974:Bromosuccinimide / Q000737:chemistry*; D002236:Carbohydrate Conformation; D006027:Glycosides / Q000138:chemical synthesis* / Q000737:chemistry; D016566:Organoselenium Compounds / Q000737:chemistry*
chemical_list: D000438:Alcohols; D001555:Benzene Derivatives; D006027:Glycosides; D016566:Organoselenium Compounds; C061132:diphenyldiselenide; D001974:Bromosuccinimide