title: Silyl ketene imines: highly versatile nucleophiles for catalytic, asymmetric synthesis.
abstract: This Minireview provides an overview on the development of silyl ketene imines and their recent applications in catalytic, enantioselective reactions. The unique structure of the ketene imine allows a diverse range of reactivity patterns and provides solutions to existing challenges in the enantioselective construction of quaternary stereogenic carbon centers and cross-benzoin adducts. A variety of reactions for which silyl ketene imines have been applied are presented with an overall goal of inspiring new uses for these underutilized nucleophiles.
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. sdenmark@iillinois.edu
authors.forename: Scott E
authors.initials: SE
authors.lastname: Denmark
authors.forename: Tyler W
authors.initials: TW
authors.lastname: Wilson