title: A study on the dose distributions in various materials from an Ir-192 HDR brachytherapy source.
abstract: Dose distributions of (192)Ir HDR brachytherapy in phantoms simulating water, bone, lung tissue, water-lung and bone-lung interfaces using the Monte Carlo codes EGS4, FLUKA and MCNP4C are reported. Experiments were designed to gather point dose measurements to verify the Monte Carlo results using Gafchromic film, radiophotoluminescent glass dosimeter, solid water, bone, and lung phantom. The results for radial dose functions and anisotropy functions in solid water phantom were consistent with previously reported data (Williamson and Li). The radial dose functions in bone were affected more by depth than those in water. Dose differences between homogeneous solid water phantoms and solid water-lung interfaces ranged from 0.6% to 14.4%. The range between homogeneous bone phantoms and bone-lung interfaces was 4.1% to 15.7%. These results support the understanding in dose distribution differences in water, bone, lung, and their interfaces. Our conclusion is that clinical parameters did not provide dose calculation accuracy for different materials, thus suggesting that dose calculation of HDR treatment planning systems should take into account material density to improve overall treatment quality.
authors.affiliation: Department of Biomedical Imaging and Radiological Science, China Medical University Hospital, Taichung, Taiwan, ROC.
authors.forename: Shih-Ming
authors.initials: SM
authors.lastname: Hsu
authors.forename: Chin-Hui
authors.initials: CH
authors.lastname: Wu
authors.forename: Jeng-Hung
authors.initials: JH
authors.lastname: Lee
authors.forename: Ya-Ju
authors.initials: YJ
authors.lastname: Hsieh
authors.forename: Chun-Yen
authors.initials: CY
authors.lastname: Yu
authors.forename: Yi-Jen
authors.initials: YJ
authors.lastname: Liao
authors.forename: Li-Cheng
authors.initials: LC
authors.lastname: Kuo
authors.forename: Ji-An
authors.initials: JA
authors.lastname: Liang
authors.forename: David Y C
authors.initials: DY
authors.lastname: Huang
mesh_terms: D016880:Anisotropy; D001842:Bone and Bones / Q000528:radiation effects; D001918:Brachytherapy / Q000379:methods*; D003198:Computer Simulation; D005373:Film Dosimetry / Q000379:methods; D005898:Glass; D006801:Humans; D007496:Iridium Radioisotopes / Q000494:pharmacology*; D008027:Light; D049449:Luminescence; D008168:Lung / Q000528:radiation effects; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D011874:Radiometry / Q000379:methods; D011879:Radiotherapy Dosage; D014867:Water / Q000737:chemistry
chemical_list: D007496:Iridium Radioisotopes; D014867:Water