title: Novel methods for assessment of right heart structure and function in pulmonary hypertension.
abstract: Long-term increases in pulmonary vascular resistance and pulmonary arterial pressure resulting from structural alterations and abnormal vasoreactivity of the pulmonary vasculature may lead to right ventricular (RV) remodeling. Conventional methods of assessment of RV structure and function do not provide sensitive markers of RV remodeling for prognostic information. Advances in cardiac imaging have provided the capability to obtain quantitative information on the RV structure and function. This article reviews the clinical conditions that result in PH and discusses the novel and emerging methods for the assessment of right heart structure and function in PH in infants and children.
authors.affiliation: Department of Pediatrics, Washington University School of Medicine, St Louis, MO, USA. singh_g@kids.wustl.edu
authors.forename: Gautam K
authors.initials: GK
authors.lastname: Singh
authors.forename: Philip T
authors.initials: PT
authors.lastname: Levy
authors.forename: Mark R
authors.initials: MR
authors.lastname: Holland
authors.forename: Aaron
authors.initials: A
authors.lastname: Hamvas
mesh_terms: D002648:Child; D002675:Child, Preschool; D004452:Echocardiography; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging / Q000503:physiopathology; D006334:Heart Function Tests; D006801:Humans; D006976:Hypertension, Pulmonary / Q000000981:diagnostic imaging / Q000503:physiopathology*; D007223:Infant; D007231:Infant, Newborn; D012307:Risk Factors; D014655:Vascular Resistance / Q000502:physiology; D018497:Ventricular Dysfunction, Right / Q000000981:diagnostic imaging / Q000503:physiopathology*; D016278:Ventricular Function, Right / Q000502:physiology; D020257:Ventricular Remodeling / Q000502:physiology*