title: Low baseline startle in anorexia nervosa patients.
abstract: This study examined baseline startle magnitude, using eye blink response and skin conductance response in anorexia nervosa patients. Twenty female in-patients with anorexia nervosa and an equal number of female healthy controls were tested. Baseline startle response was assessed during blank screens while four startling loud sounds (a 116 dB, 1s, 250 Hz tone) were delivered with a time interval ranging from 35 to 55 s. It was investigated if BMI and state anxiety correlated with physiological responses. The clinical sample showed a lower baseline startle reflex measured with both indices, than healthy controls. Across the whole sample, a single regression model partially explained the relationship between BMI and baseline skin conductance response.
authors.affiliation: Department of Clinical Neuroscience, San Raffaele Scientific Institute, Milan, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Bellodi
authors.forename: Riccardo Maria
authors.initials: RM
authors.lastname: Martoni
authors.forename: Elisa
authors.initials: E
authors.lastname: Galimberti
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Cavallini
mesh_terms: D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000503:physiopathology*; D005260:Female; D005712:Galvanic Skin Response / Q000502:physiology*; D006801:Humans; D011930:Reaction Time / Q000502:physiology; D012018:Reflex / Q000502:physiology*; D013216:Reflex, Startle / Q000502:physiology*; D012720:Severity of Illness Index