title: Effects of the standard and endoliquor injection of estradurin on the rat prostate.
abstract: The effects of intramuscular and endoliquor routes of administration of water-soluble antiandrogenic drug estradurin on proliferative activity of the prostate were studied. Estradurin injection via both routes produced a suppressive effect on the prostate. The effect of the minimum estradurin dose injected into the liquor was most manifest and not paralleled by side effects.
authors.affiliation: Laboratory of Experimental Hormone Therapy of Tumors, Rostov Oncological Institute, the Ministry of Health and Social Development of the Russian Federation, Russia.
authors.forename: Yu N
authors.initials: YN
authors.lastname: Bordyushkov
authors.forename: I V
authors.initials: IV
authors.lastname: Kaplieva
authors.forename: L K
authors.initials: LK
authors.lastname: Trepitaki
mesh_terms: D000726:Androgen Antagonists / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D049109:Cell Proliferation / Q000187:drug effects*; D004958:Estradiol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D007273:Injections, Intramuscular; D008297:Male; D011467:Prostate / Q000166:cytology* / Q000187:drug effects; D051381:Rats
chemical_list: D000726:Androgen Antagonists; D004958:Estradiol; C008958:polyestradiol phosphate