title: Oat β-glucan increased ATPases activity and energy charge in small intestine of rats.
abstract: Dietary oat or oat products may potentially help to fight against high risk of cardiovascular diseases and β-glucan in oat was considered as a central player. The present study aimed to investigate the effects of dietary oat whole meal or β-glucan on insulin sensitivity and energy metabolism of rats. Rats were fed with control diet, oat whole meal based diet, or control diet with supplemented β-glucan for 4 weeks. Oat whole meal and β-glucan increased insulin sensitivity index. Interestingly, supplementation of oat whole meal or β-glucan induced increases in intestinal Na(+)K(+)-ATPase activity, Ca(2+)Mg(2+)-ATPase activity, and energy charge, particularly in the distal part of small intestine (ileum). Furthermore, amounts of  Bifidobacterium  and  Lactobacillus  in colon contents were elevated by oat whole meal or β-glucan. These findings provide an insight into that β-glucan increased insulin sensitivity and benefited intestinal health.
authors.affiliation: College of Food Science and Engineering,  Northwest A&F University , 28 Xinong Road, Yangling 712100, Shaanxi, China.
authors.forename: Pei-Pei
authors.initials: PP
authors.lastname: Zhang
authors.forename: Xin-Zhong
authors.initials: XZ
authors.lastname: Hu
authors.forename: Hong-Min
authors.initials: HM
authors.lastname: Zhen
authors.forename: Chao
authors.initials: C
authors.lastname: Xu
authors.forename: Ming-Tao
authors.initials: MT
authors.lastname: Fan
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D018554:Avena / Q000378:metabolism*; D001644:Bifidobacterium / Q000254:growth & development; D003106:Colon / Q000382:microbiology; D004043:Dietary Fiber / Q000378:metabolism; D004734:Energy Metabolism; D006801:Humans; D007421:Intestine, Small / Q000201:enzymology* / Q000378:metabolism / Q000382:microbiology; D007778:Lactobacillus / Q000254:growth & development; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D015854:Up-Regulation; D047071:beta-Glucans / Q000378:metabolism*
chemical_list: D004043:Dietary Fiber; D047071:beta-Glucans; D000251:Adenosine Triphosphatases