title: [Comparative epidemiological study of the tuberculosis - migrant and native subjects in Guadeloupe from 2006 to 2011].
abstract: BACKGROUND
  Most of the migrants residing in Guadeloupe are from neighboring Caribbean islands, some of which are characterized by a high incidence of tuberculosis. The objective of this retrospective and observational study was to define the epidemiological characteristics of tuberculosis affecting migrant and native populations in Guadeloupe.
  
  
  METHODS
  We describe all cases of tuberculosis in Guadeloupe identified in these two populations between 1 July 2006 and 30 June 2011.
  
  
  RESULTS
  The incidence of TB among migrants in Guadeloupe was seven times higher than that in native subjects in 2010 (33.4 vs. 5.5 new cases/100,000 inhabitants). Tuberculosis affecting the migrant population was characterized by young age of the patients (42 vs. 55 years) and a significant proportion of co-infection by the human immunodeficiency virus (HIV) (47 vs. 14%, P<0.001). Among the patient population studied, the HIV infection increased the risk of developing severe tuberculosis (adjusted odds ratio: 2.9; 95%CI: 1.2-6.8). Moreover, HIV infection was also a risk factor for death where the infection was not controlled (CD4 count <200 units per microliter; adj risk ratio: 3.9; 1.2-12.4).
  
  
  CONCLUSIONS
  This study shows that the migrant population in Guadeloupe is at increased risk of tuberculosis and should be considered as a priority target for tuberculosis control program.
authors.affiliation: Service de Pneumologie, CHU de Pointe-à-Pitre, route de Chauvel, 97159 Pointe-à-Pitre Cedex, Guadeloupe. gilbert.cadelis@chu-guadeloupe.fr
authors.forename: G
authors.initials: G
authors.lastname: Cadelis
authors.forename: E
authors.initials: E
authors.lastname: Rossigneux
authors.forename: J
authors.initials: J
authors.lastname: Millet
authors.forename: N
authors.initials: N
authors.lastname: Rastogi
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000453:epidemiology; D000328:Adult; D060085:Coinfection; D005260:Female; D019430:Guadeloupe / Q000453:epidemiology; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D014171:Transients and Migrants / Q000706:statistics & numerical data*; D014376:Tuberculosis / Q000453:epidemiology*