title: Developmental origins of health and adult disease: what should neonatologists/paediatricians be considering about the long-term health of their patients?
abstract: The developmental origins of health and disease hypothesis is now strongly supported by both animal and human evidence, and as a consequence, obstetricians, neonatologists and paediatricians need to consider the impact that the in utero and early post-natal environment can have on later renal, cardiovascular and metabolic health. Four common clinical scenarios were provided along with animal and human evidence identifying long-term health implications. Suggestions as to how we should translate this growing body of evidence into practice are provided.
authors.affiliation: Department of Neonatology, Canberra Hospital, Woden, Australian Capital Territory, Australia. alison.kent@act.gov.au
authors.forename: Alison L
authors.initials: AL
authors.lastname: Kent
mesh_terms: D000328:Adult; D004194:Disease / Q000209:etiology; D005260:Female; D047109:Fetal Development; D006262:Health; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D009359:Neonatology; D010372:Pediatrics; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D018570:Risk Assessment