title: Activities of clotting, fibrinolytic, and anticoagulant components of plasma hemostasis in patients with degenerative diseases of large joints.
abstract: Analysis of plasma hemostasis parameters was carried out in 110 patients with degenerative diseases of hip or knee joints hospitalized for initial endoprosthetics. Molecular markers of clotting and fibrinolysis and physiological anticoagulants were studied. Activities of all components of plasma hemostasis were normal in 29.4% patients. In 54.1% patients, high clotting activity was compensated for by adequate fibrinolysis activity. High thrombin formation was compensated for by high consumption of physiological anticoagulants in 10.1% patients. In 6.4% patients, high clotting activity was not paralleled by high fibrinolytic activity.
authors.affiliation: V. D. Chaklin Ural Institute of Traumatology and Orthopedics, Ministry of Health Care and Social Development of the Russian Federation, Ekaterinburg, Russia. aip.hemolab@mail.ru
authors.forename: I P
authors.initials: IP
authors.lastname: Antropova
authors.forename: B G
authors.initials: BG
authors.lastname: Yushkov
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D001777:Blood Coagulation / Q000502:physiology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005342:Fibrinolysis / Q000502:physiology*; D006487:Hemostasis / Q000502:physiology*; D006621:Hip Joint / Q000503:physiopathology*; D006801:Humans; D007592:Joint Diseases / Q000503:physiopathology*; D007719:Knee Joint / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010314:Partial Thromboplastin Time
chemical_list: D015415:Biomarkers