title: The pig as an experimental model for clinical craniofacial research.
abstract: The pig represents a useful, large experimental model for biomedical research. Recently, it has been used in different areas of biomedical research. The aim of this study was to review the basic anatomical structures of the head region in the pig in relation to their use in current research. Attention was focused on the areas that are frequently affected by pathological processes in humans: the oral cavity with teeth, salivary gland, orbit, nasal cavity and paranasal sinuses, maxilla, mandible and temporomandibular joint. Not all of the structures have an equal morphology in the pig and human, and these morphological dissimilarities must be taken into account before choosing the pig as an experimental model for regenerative medicine.
authors.affiliation: Institute of Animal Physiology and Genetics, vvi, Academy of Sciences of Czech Republic, Brno, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Štembírek
authors.forename: M
authors.initials: M
authors.lastname: Kyllar
authors.forename: I
authors.initials: I
authors.lastname: Putnová
authors.forename: L
authors.initials: L
authors.lastname: Stehlík
authors.forename: M
authors.initials: M
authors.lastname: Buchtová
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D006801:Humans; D009055:Mouth / Q000033:anatomy & histology* / Q000473:pathology / Q000503:physiopathology; D009666:Nose / Q000033:anatomy & histology* / Q000473:pathology / Q000503:physiopathology; D009668:Nose Diseases / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D009916:Orbital Diseases / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D012886:Skull / Q000033:anatomy & histology* / Q000473:pathology / Q000503:physiopathology; D009057:Stomatognathic Diseases / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D013552:Swine / Q000033:anatomy & histology*