title: Non-covalent functionalisation of monolithic silica for the development of carbon nanotube HPLC stationary phases.
abstract: In this paper, an effective and simple method was used for the immobilization of single wall carbon nanotubes (SWCNTs) on a monolithic HPLC material containing 2 μm macropore sizes and 13 nm mesopore sizes. The chromatographic support was coated with ultra short SWCNTs in a noncovalent way to preserve the sp(2) nanotube structure and thus their physico-chemical properties. It was demonstrated that the amino-surface of the monolith stabilized with 1-methyl-2-pyrrolidinone efficiently and stably adsorbed SWCNTs onto the chromatographic support. It was shown that this novel stationary phase was very useful for the HPLC isocratic mode separation of a series of small aromatic compounds in a very short analysis time. The comparison with a classical equivalent C18 monolithic column showed that the SWCNT column presented the best efficiency in similar chromatographic conditions.
authors.affiliation: Univ Franche-Comté, F-25000 Besançon, France; CHU Besançon, Pôle Pharmaceutique, F-25000 Besançon, France.
authors.forename: Claire
authors.initials: C
authors.lastname: André
authors.forename: Gwenaelle
authors.initials: G
authors.lastname: Lenancker
authors.forename: Yves Claude
authors.initials: YC
authors.lastname: Guillaume
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D037742:Nanotubes, Carbon / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D037742:Nanotubes, Carbon; D012822:Silicon Dioxide