title: No genetic evidence for Neuregulin 3 conferring risk of schizophrenia in the Chinese population.
abstract: We genotyped 13 single nucleotide polymorphisms (SNPs) within Neuregulin 3 (NRG3) to investigate the association between NRG3 and schizophrenia in 488 patients and 506 controls in Northwest China. No association was detected either in SNPs or in haplotypes. Our study provided no evidence that NRG3 confers a risk of schizophrenia susceptibility in the Han Chinese population.
authors.affiliation: Department of Genetics and Molecular Biology, Xi'an Jiaotong University School of Medicine, Xi'an, Shaanxi 710061, PR China.
authors.forename: Rui
authors.initials: R
authors.lastname: Zhang
authors.forename: Xiao-Yun
authors.initials: XY
authors.lastname: Du
authors.forename: Jie
authors.initials: J
authors.lastname: Yu
authors.forename: Nan
authors.initials: N
authors.lastname: Xu
authors.forename: Yue-Wen
authors.initials: YW
authors.lastname: Zheng
authors.forename: Ya-Ling
authors.initials: YL
authors.lastname: Zhao
authors.forename: Huan
authors.initials: H
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Ma
mesh_terms: D000328:Adult; D044466:Asian People / Q000235:genetics; D002681:China; D005260:Female; D056726:Genetic Association Studies; D005838:Genotype; D006239:Haplotypes; D006801:Humans; D008297:Male; D020880:Neuregulins / Q000235:genetics / Q000502:physiology*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D012559:Schizophrenia / Q000235:genetics*
chemical_list: C486357:NRG3 protein, human; D020880:Neuregulins