title: A base-promoted tandem cycloaddition/air oxidation reaction of electron-deficient conjugated enynes and hydrazines: synthesis of highly substituted pyrazoles.
abstract: Rapid access: A base-mediated cycloaddition/oxidation reaction of hydrazines and electron-deficient 1,3-conjugated enynes gives pyrazole derivatives, some of which are not easily accessible by other methods (see scheme). The reaction conditions are mild, thus enabling a variety of functional groups to be tolerated.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, 3663 N. Zhongshan Road, Shanghai 200062, PR China.
authors.forename: Xiuzhao
authors.initials: X
authors.lastname: Yu
authors.forename: Junliang
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D061565:Cycloaddition Reaction; D004583:Electrons; D006834:Hydrazines / Q000737:chemistry*; D010084:Oxidation-Reduction; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000480:Alkynes; D006834:Hydrazines; D011720:Pyrazoles