title: Forces created by mandibular advancement devices in OSAS patients: a pilot study during sleep.
abstract: BACKGROUND
  The aim of this study was to measure forces created by progressive mandibular advancement with an oral device, during natural sleep, in a sample of adult patients with obstructive sleep apnea syndrome (OSAS).
  
  
  METHODS
  A pressure transducer system was placed on the acrylic arms of a two-piece oral appliance (Herbst type) used by nine moderate to severe OSAS patients, in addition to all captors routinely used for polysomnography. Strains on the left and right sides were collected, during stable sleep stages without arousal, for each step of 1 mm advancement.
  
  
  RESULTS
  The mean force in this sample was 1.18 N/mm and showed an almost linear evolution. Measurements showed intra- and inter-individual variability.
  
  
  CONCLUSIONS
  The force values recorded in this study may explain the occlusal and skeletal side effects associated with long-term use of these oral appliances. They illustrate the influence of the extent of mandibular advancement, and indicate a possible dose-dependent effect.
authors.affiliation: juliacohenlevy@yahoo.fr
authors.forename: J
authors.initials: J
authors.lastname: Cohen-Levy
authors.forename: B
authors.initials: B
authors.lastname: Pételle
authors.forename: J
authors.initials: J
authors.lastname: Pinguet
authors.forename: E
authors.initials: E
authors.lastname: Limerat
authors.forename: B
authors.initials: B
authors.lastname: Fleury
mesh_terms: D000328:Adult; D001143:Arousal / Q000502:physiology; D001696:Biomechanical Phenomena; D001732:Bite Force; D005260:Female; D006801:Humans; D008297:Male; D019186:Mandibular Advancement / Q000295:instrumentation*; D008875:Middle Aged; D017090:Occlusal Splints; D016382:Orthodontic Appliance Design; D010865:Pilot Projects; D017286:Polysomnography; D020181:Sleep Apnea, Obstructive / Q000503:physiopathology* / Q000628:therapy*; D014087:Tooth Movement Techniques