title: Neuroprotective role of erythropoietin in neonates.
abstract: This review summarizes target populations of neonates for which erythropoietin (Epo) neuroprotective therapy might be of benefit, and the mechanisms by which Epo functions as a neuroprotective agent. Potential risks of Epo are reviewed. Finally, the progression of Epo neuroprotection from preclinical studies to translational studies is discussed.
authors.affiliation: Department of Paediatrics, Neonatology Division, University of Washington, Seattle, Washington 98195-6320, USA. sjuul@uw.edu
authors.forename: Sandra
authors.initials: S
authors.lastname: Juul
mesh_terms: D001921:Brain / Q000187:drug effects / Q000378:metabolism; D004921:Erythropoietin / Q000008:administration & dosage / Q000378:metabolism / Q000502:physiology* / Q000627:therapeutic use; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000209:etiology / Q000517:prevention & control; D007231:Infant, Newborn / Q000378:metabolism*; D007232:Infant, Newborn, Diseases / Q000209:etiology / Q000517:prevention & control; D007235:Infant, Premature, Diseases / Q000209:etiology / Q000517:prevention & control; D009422:Nervous System Diseases / Q000209:etiology / Q000517:prevention & control; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000378:metabolism / Q000627:therapeutic use; D012307:Risk Factors
chemical_list: D018696:Neuroprotective Agents; D004921:Erythropoietin