title: Vascularization of hepatocellular carcinoma tissue depends on its differentiation degree.
abstract: Quantitative characteristics of vessels in hepatocellular carcinoma and adjacent liver tissue were studied by morphometric methods after immunohistochemical staining for CD34 and CD105. The number of immunopositive vessels decreased with reduction of tumor histological differentiation degree.
authors.affiliation: V. I. Kulakov Center of Obstetrics, Gynecology, and Perinatology, the Ministry of Health Care and Social Development of the Russian Federation, Moscow, Russia. ashegolev@oparina4ru
authors.forename: A I
authors.initials: AI
authors.lastname: Shchyogolev
authors.forename: E A
authors.initials: EA
authors.lastname: Dubova
authors.forename: U N
authors.initials: UN
authors.lastname: Tumanova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015703:Antigens, CD / Q000378:metabolism; D018952:Antigens, CD34 / Q000378:metabolism; D006528:Carcinoma, Hepatocellular / Q000098:blood supply* / Q000145:classification / Q000473:pathology; D002454:Cell Differentiation / Q000502:physiology; D000071063:Endoglin; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000098:blood supply* / Q000145:classification / Q000473:pathology; D008297:Male; D008853:Microscopy; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000503:physiopathology*; D011956:Receptors, Cell Surface / Q000378:metabolism
chemical_list: D015703:Antigens, CD; D018952:Antigens, CD34; C064206:ENG protein, human; D000071063:Endoglin; D011956:Receptors, Cell Surface