title: Neurogenic stunned myocardium after embolization in two children with vein of Galen aneurysmal malformation.
abstract: BACKGROUND
  This study reports the first cases of neurogenic stunned myocardium in two children with vein of Galen aneurysmal malformation after interventional treatment.
  
  
  METHODS
  Two newborns with vein of Galen aneurysmal malformation and high output cardiac failure developed a severe reversible left ventricular dysfunction shortly after embolization, concurrently with acute hydrocephalus.
  
  
  RESULTS
  There was a resolution of the cardiac symptoms of left ventricular dysfunction within a few days under treatment with milrinone and dobutamine.
  
  
  CONCLUSIONS
  Reversible left ventricular dysfunction is observed in adult patients mainly after subarachnoid hemorrhage and is called neurogenic stunned myocardium (NSM). Other forms of brain injuries have also been identified accounting for this condition in adults. In pediatric population especially with specific cerebral diseases, NSM may be underdiagnosed.
authors.affiliation: Department of Neonatal and Pediatric Intensive Care Unit, Klinikum Duisburg, Zu den Rehwiesen 9, 47055 Duisburg, Germany. f.brevis@klinikum-duisburg.de
authors.forename: Francisco
authors.initials: F
authors.lastname: Brevis Nuñez
authors.forename: Eva
authors.initials: E
authors.lastname: Tschiedel
authors.forename: Ursula
authors.initials: U
authors.lastname: Felderhoff-Mueser
authors.forename: Ulrich
authors.initials: U
authors.lastname: Neudorf
authors.forename: René
authors.initials: R
authors.lastname: Chapot
authors.forename: Christian
authors.initials: C
authors.lastname: Dohna-Schwake
mesh_terms: D002316:Cardiotonic Agents / Q000627:therapeutic use; D002533:Cerebral Angiography / Q000379:methods*; D003937:Diagnosis, Differential; D004280:Dobutamine / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D002532:Intracranial Aneurysm / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D020105:Milrinone / Q000627:therapeutic use; D017682:Myocardial Stunning / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D016896:Treatment Outcome; D054080:Vein of Galen Malformations / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D002316:Cardiotonic Agents; D004280:Dobutamine; D020105:Milrinone