title: Kinetic inertness of the Mn2+ complexes formed with AAZTA and some open-chain EDTA derivatives.
abstract: The results of systematic equilibrium, kinetic, and relaxometric investigations carried out on the Mn(2+) complexes of open-chain and AAZTA ligands indicate that the [Mn(CDTA)](2-) complex has satisfactorily high kinetic inertness (t(1/2) = 12 h at pH = 7.4), which, in turn, may allow its use as a contrast agent in the field of magnetic resonance imaging (as a replacement for Gd(3+)-based agents).
authors.affiliation: Department of Inorganic and Analytical Chemistry, Faculty of Science and Technology, University of Debrecen, Egyetem tér 1, P.O. Box 21, Debrecen H-4010, Hungary. ferenc.kalman@science.unideb.hu
authors.forename: Ferenc K
authors.initials: FK
authors.lastname: Kálmán
authors.forename: Gyula
authors.initials: G
authors.lastname: Tircsó
mesh_terms: D003287:Contrast Media / Q000737:chemistry; D056831:Coordination Complexes / Q000737:chemistry*; D004492:Edetic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D008024:Ligands; D008345:Manganese / Q000737:chemistry*
chemical_list: D003287:Contrast Media; D056831:Coordination Complexes; D008024:Ligands; D008345:Manganese; C005390:CDTA; D004492:Edetic Acid