title: [Inflammatory choroidal neovascularisations].
abstract: Inflammation plays a key role in the induction of choroidal neovascular membranes (CNV). This explains why each form of posterior uveitis may lead to CNV formation. Diseases like presumed ocular histoplasmosis syndrome (POHS), multifocal choroiditis (MFC) or punctate inner choroidopathy (PIC) carry a high risk of CNV creation. Inflammatory processes mostly cause classical membranes. Because of the classical membrane form, smaller membrane size and the younger age of the patients' inflammatory membranes are often better treatable than membranes in AMD patients. In the times before VEGF inhibition inflammatory membranes were treated with argon laser coagulation and later with PDT. Nowadays better visual acuity results are achievable through VEGF inhibitor injections with or without PDT. This is proven by a few publications with greater numbers of patients because of the rarity of the diseases and several case reports in the literature. In addition to CNV treatment the control of intraocular inflammation should never be forgotten because it forms the leading CNV trigger.
authors.affiliation: Klinik für Augenheilkunde, Charité Universitätsmedizin Berlin. Sibylle.Winterhalter@charite.de
authors.forename: S
authors.initials: S
authors.lastname: Winterhalter
authors.forename: A M
authors.initials: AM
authors.lastname: Joussen
authors.forename: U
authors.initials: U
authors.lastname: Pleyer
authors.forename: N
authors.initials: N
authors.lastname: Stübiger
mesh_terms: D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D020256:Choroidal Neovascularization / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D002833:Choroiditis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000627:therapeutic use*
chemical_list: D020533:Angiogenesis Inhibitors; D017319:Photosensitizing Agents