title: Chapter 2 UK RRT prevalence in 2010: national and centre-specific analyses.
abstract: BACKGROUND
  This chapter describes the characteristics of adult patients on renal replacement therapy (RRT) in the UK in 2010.
  
  
  METHODS
  Data were electronically collected from all 72 renal centres within the UK. Cross-sectional and longitudinal analyses were performed to describe the demographics of prevalent RRT patients in 2010 at centre and national level. Age and gender standardised ratios for prevalence rates per million population per year were calculated.
  
  
  RESULTS
  There were 50,965 adult patients receiving RRT in the UK on 31st December 2010. The UK prevalence of RRT (including paediatric patients) was 832 pmp. This represented an annual increase in prevalent numbers of approximately 4% although there was significant variation between centres and regions. From 2009 to 2010 there was a 1.5% increase in the number of patients on haemodialysis (HD), a 3.2% fall in peritoneal dialysis (PD) patients and a 5.4% increase in patients with a functioning transplant. The number of patients receiving home HD has increased 23% since 2009. Median RRT vintage was 5.6 years. The median age was 57.9 years (HD 66.3 years, PD 61.7 years and transplant 51.2 years) compared to 55 years in 2000. Prevalence rates in males exceeded those in females. The most common identifiable renal diagnosis was biopsyproven glomerulonephritis (16.0%), followed by diabetes (14.9%). Transplantation was the most common treatment modality (48%), HD in 44% and PD 8%.
  
  
  CONCLUSIONS
  The HD and transplant population continued to expand whilst the PD population contracted. There were national, regional and dialysis centre level variations in prevalence rates. Prevalent patients were on average 4 years older than 10 years ago. This has implications for service planning and ensuring equity of care for RRT patients.
authors.affiliation: UK Renal Registry, Bristol, UK. renalregistry@renalregistry.nhs.uk
authors.forename: Clare
authors.initials: C
authors.lastname: Castledine
authors.forename: Anna
authors.initials: A
authors.lastname: Casula
authors.forename: Damian
authors.initials: D
authors.lastname: Fogarty
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D002391:Catchment Area, Health; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003928:Diabetic Nephropathies / Q000453:epidemiology / Q000628:therapy; D005260:Female; D005919:Glomerular Filtration Rate; D006436:Hemodialysis Units, Hospital / Q000706:statistics & numerical data; D006801:Humans; D007676:Kidney Failure, Chronic / Q000453:epidemiology / Q000628:therapy; D016030:Kidney Transplantation / Q000706:statistics & numerical data; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012042:Registries / Q000706:statistics & numerical data*; D017582:Renal Replacement Therapy / Q000706:statistics & numerical data*; D017678:Sex Distribution; D012959:Socioeconomic Factors; D013997:Time Factors; D006113:United Kingdom / Q000453:epidemiology; D055815:Young Adult