title: Oleanane saponins from Bellis sylvestris Cyr. and evaluation of their phytotoxicity on Aegilops geniculata Roth.
abstract: Six oleanane saponins were isolated for the first time from leaves of Bellis sylvestris Cyr., the southern daisy. Their structures were established by the extensive use of 2D-NMR experiments, including COSY, TOCSY, NOESY, HSQC, HMBC, CIGAR, H2BC, and HSQC-TOCSY, along with Q-TOF HRMS² analysis. All of the compounds are constituted by bayogenin as aglycone, and characterized by the presence of an oligosaccharide moiety, consisting of two to four sugar unities esterified at the C-28 carboxyl carbon. One of the isolated compounds is a bisdesmoside containing an additional sugar moiety at the C-3 carbon. The phytotoxic activity assayed against Aegilops geniculata Roth., a coexisting test species, has been evaluated revealing that all the compounds, at the highest concentrations, showed strong phytotoxicity against the leaf development.
authors.affiliation: Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, via Vivaldi 43, I-81100 Caserta, Italy.
authors.forename: Monica
authors.initials: M
authors.lastname: Scognamiglio
authors.forename: Brigida
authors.initials: B
authors.lastname: D'Abrosca
authors.forename: Vittorio
authors.initials: V
authors.lastname: Fiumano
authors.forename: Angela
authors.initials: A
authors.lastname: Chambery
authors.forename: Valeria
authors.initials: V
authors.lastname: Severino
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Tsafantakis
authors.forename: Severina
authors.initials: S
authors.lastname: Pacifico
authors.forename: Assunta
authors.initials: A
authors.lastname: Esposito
authors.forename: Antonio
authors.initials: A
authors.lastname: Fiorentino
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D004305:Dose-Response Relationship, Drug; D008968:Molecular Conformation; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D006109:Poaceae / Q000187:drug effects*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D013237:Stereoisomerism
chemical_list: D012503:Saponins; C413246:oleanane; D009828:Oleanolic Acid