title: [Retrospective study of ocular complications in patients with human immunodeficiency virus infection before and after HAART].
abstract: OBJECTIVE
  To describe ocular complications in patients with human immunodeficiency virus (HIV) infection before and after highly active antiretroviral therapy(HAART).
  
  
  METHODS
  We retrospectively reviewed the medical records of 261 patients who underwent HAART and visited our clinic between April, 2007 and March, 2010, and recorded ocular complications, CD4 cell counts, visual acuity and other relevant patient information.
  
  
  RESULTS
  Befor HAART patients were found to have the following conditions: HIV retinopathy (41 cases), cytomegalovirus (CMV) retinitis (23 cases), and others (6 cases); and after HAART HIV retinopathy (5 cases), CMV retinitis (16 cases), Immune recovery uveitis(IRU) (4 cases), and others(9 cases). The average CD4+ T-cell counts at diagnosis of CMV retinitis were 45.2/microl before and 116.7/microl after HAART.
  
  
  CONCLUSIONS
  Since a substantial number of patients develop CMV retinitis after the initiation of HAART, we need to examine patients to check for either the onset or reactivation of CMV retinitis and IRU even after HAART.
authors.affiliation: Department of Ophthalmology, National Hospital Organization Osaka National Hospital, Japan. h_ayumi03@onh.go.jp
authors.forename: Ayumi
authors.initials: A
authors.lastname: Hamamotoo
authors.forename: Misako
authors.initials: M
authors.lastname: Tatebayashi
authors.forename: Asako
authors.initials: A
authors.lastname: Uehira
authors.forename: Sato
authors.initials: S
authors.lastname: Kuroda
authors.forename: Yuko
authors.initials: Y
authors.lastname: Morimoto
authors.forename: Tomoya
authors.initials: T
authors.lastname: Nakagawa
authors.forename: Shinichi
authors.initials: S
authors.lastname: Usui
authors.forename: Masaki
authors.initials: M
authors.lastname: Watanabe
authors.forename: Kumiko
authors.initials: K
authors.lastname: Kazuo
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Otori
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D023241:Antiretroviral Therapy, Highly Active; D018791:CD4 Lymphocyte Count; D017726:Cytomegalovirus Retinitis / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000453:epidemiology* / Q000821:virology; D012189:Retrospective Studies; D012737:Sex Factors; D014605:Uveitis / Q000453:epidemiology* / Q000209:etiology; D055815:Young Adult