title: Parent and self-report health-related quality of life measures in young patients with Tourette syndrome.
abstract: Tourette syndrome is a neurodevelopmental disorder characterized by tics and comorbid behavioral problems. This study compared child- and parent-reported quality of life and everyday functioning. We assessed 75 children with Tourette syndrome, of which 42 (56%) had comorbid conditions (obsessive-compulsive disorder = 25; attention-deficit hyperactivity disorder = 6; both comorbidities = 4). All patients completed psychometric instruments, including the Gilles de la Tourette Syndrome-Quality of Life Scale for Children and Adolescents (child report) and the Child Tourette's Syndrome Impairment Scale (parent report). Data were compared for patients with pure Tourette syndrome, Tourette syndrome + obsessive-compulsive disorder, Tourette syndrome + attention-deficit hyperactivity disorder, and Tourette syndrome + both comorbidities. There were no group differences in quality of life. However, there were differences for total, school, and home activities impairment scores. Children and parents may not share similar views about the impact of Tourette syndrome on functioning. The measurement of health-related quality of life in Tourette syndrome is more complex in children than adults.
authors.affiliation: 1Department of Neuropsychiatry, BSMHFT and University of Birmingham, United Kingdom.
authors.forename: Andrea E
authors.initials: AE
authors.lastname: Cavanna
authors.forename: Chiara
authors.initials: C
authors.lastname: Luoni
authors.forename: Claudia
authors.initials: C
authors.lastname: Selvini
authors.forename: Rosanna
authors.initials: R
authors.lastname: Blangiardo
authors.forename: Clare M
authors.initials: CM
authors.lastname: Eddy
authors.forename: Paola R
authors.initials: PR
authors.lastname: Silvestri
authors.forename: Paola V
authors.initials: PV
authors.lastname: Cali'
authors.forename: Emanuela
authors.initials: E
authors.lastname: Gagliardi
authors.forename: Umberto
authors.initials: U
authors.lastname: Balottin
authors.forename: Francesco
authors.initials: F
authors.lastname: Cardona
authors.forename: Renata
authors.initials: R
authors.lastname: Rizzo
authors.forename: Cristiano
authors.initials: C
authors.lastname: Termine
mesh_terms: D000293:Adolescent; D000328:Adult; D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications / Q000523:psychology; D002648:Child; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000150:complications / Q000523:psychology; D010290:Parents; D011594:Psychometrics; D011788:Quality of Life; D057566:Self Report; D012720:Severity of Illness Index; D020323:Tics / Q000150:complications / Q000523:psychology*; D005879:Tourette Syndrome / Q000150:complications / Q000523:psychology*