title: [Effects of Yupei Qisun Sequential Method of Chinese medicine on correlated indices of repeated implantation failure patients in the fresh cycle].
abstract: OBJECTIVE
  To study the clinical effects of Yupei Qisun Sequential Method (YQSM, by Shen supplementing and Pi invigorating) of Chinese medicine on correlated indices of repeated implantation failure patients in the fresh cycle.
  
  
  METHODS
  Sixty patients with more than three failure cycles of in virto fertilization and embryo transfer (IVF-ET) or intracytoplasmic sperm injection (ICSI) were recruited. They were assigned to the treatment group (treated by IVF/ICSI and Chinese medicine) and the control group (treated by IVF/ICSI alone), 30 in each group. The total dose of gonadotropin (Gn), the days of controlled ovary hyperstimulation (COH), the thickness of endometrium on the day of embryo transplantation, the number of retrieved oocytes, the fertilization number, the embryo number, the high quality embryo number, the pregnancy rate, and the implantation rate were compared.
  
  
  RESULTS
  In the treatment group the numbers of embryo and high quality embryo were 7.5 +/- 4.9 and 5.1 +/- 3.2 respectively, which were both higher than those of the control group with significant difference (5.1 +/- 3.2, 3.2 +/- 1.8; P < 0.05). No significant difference existed in aspects of the total numbers of Gn, the days of COH, the thickness of endometrium on the day of embryo transplantation, the numbers of retrieved oocytes, the fertilization number, the pregnancy rate, and the implantation rate between the two groups (P > 0.05).
  
  
  CONCLUSIONS
  YQSM combined with COH could improve the quantity and the quality of embryos, which was promising to increase the accumulative pregnancy rate of RIF patients.
authors.affiliation: Department of Gynecology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai.
authors.forename: Sha
authors.initials: S
authors.lastname: Yu
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Kuang
authors.forename: Cong
authors.initials: C
authors.lastname: Qi
mesh_terms: D000328:Adult; D004624:Embryo Transfer; D004717:Endometrium / Q000502:physiology; D005260:Female; D005307:Fertilization in Vitro; D006062:Gonadotropins / Q000008:administration & dosage; D006801:Humans; D008516:Medicine, Chinese Traditional / Q000379:methods*; D054315:Oocyte Retrieval; D010062:Ovulation Induction; D011247:Pregnancy; D018873:Pregnancy Rate; D020554:Sperm Injections, Intracytoplasmic; D017211:Treatment Failure
chemical_list: D006062:Gonadotropins