title: [Fat embolism syndrome after bone fractures].
abstract: OBJECTIVE
  To review the incidence, clinical features, diagnosis, therapy and mortality rates of fat embolism syndrome (FES) in a tertiary referral hospital in the last decade.
  
  
  METHODS
  Retrospective and descriptive study of patients diagnosed with post-traumatic FES between january 2001 and december 2011.
  
  
  RESULTS
  A total of 19 patients, 16 men and 3 women, with an average age of 27 years were evaluated. All had long bone fractures, multiple in 78.9%, as a result of multiple injuries. Respiratory symptoms were the most frequent (89.5%), followed by neurological symptoms (68.4%) and petechial rash (63.2%). The average time of presentation of the syndrome after admission was 42 hours. All patients underwent early stabilisation of the fracture prior to the embolic event. Steroids prophylaxis was not used in any of the cases. Definitive surgical treatment had mean delay of 7 days. The mean hospital stay was 34 days. The overall incidence of FES was 0.14%, and mortality was 10.5%.
  
  
  CONCLUSIONS
  Post-traumatic FES mainly affected young patients with multiple injuries and long bone fractures. They all had symptoms of the classic clinical triad (respiratory, neurological, rash) after an initial asymptomatic period of less than 2 days. The overall incidence was low.
authors.affiliation: Servicio de Medicina Interna, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Campo-López
authors.forename: P
authors.initials: P
authors.lastname: Flors-Villaverde
authors.forename: J R
authors.initials: JR
authors.lastname: Calabuig-Alborch
mesh_terms: D000328:Adult; D004620:Embolism, Fat / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D005260:Female; D005264:Femoral Fractures / Q000150:complications*; D006801:Humans; D015994:Incidence; D008297:Male; D012189:Retrospective Studies; D013577:Syndrome; D013978:Tibial Fractures / Q000150:complications*; D016896:Treatment Outcome