title: Comparison of posterior capsule opacification between a 1-piece and a 3-piece microincision intraocular lens.
abstract: OBJECTIVE
  To compare the intensity of posterior capsular opacification (PCO) between a 1-piece and a 3-piece microincision cataract surgery intraocular lens (MICS IOL) in a prospective randomised study.
  
  
  METHODS
  80 eyes of 40 patients with age-related cataract were enrolled in this study. Each patient received a 1-piece MICS IOL (AF-1 NY-60, Hoya, Tokyo, Japan) in one eye and a 3-piece MICS IOL (AF-1 iMICS Y-60H, Tokyo, Hoya) in the other eye. At the 1-year follow-up, the patients were examined at the slit lamp, visual acuity was determined and standardised high-resolution digital retroillumination images were taken for objective quantification of regeneratory PCO using an automated image analysis software (AQUA).
  
  
  RESULTS
  The mean regeneratory PCO score (1-piece IOL: 0.2, 3-piece IOL 0.3, p=0.7) and the neodymium:yttrium-aluminium-garnet laser capsulotomy rate (two cases in 3-piece IOL group; p=0.5) were comparable low for both IOLs. Capsular folds occurred significantly more often in the 3-piece IOL group (p=0.02).
  
  
  CONCLUSIONS
  Modification of the MICS IOL from a 3-piece to a 1-piece haptic design caused in short term no significant change in PCO amount. Compared with the 3-piece IOL, the 1-piece IOL led to significantly less capsular folds 1 year after surgery.
authors.affiliation: Department of Ophthalmology, Hietzing Hospital, Wolkersbergenstrasse 1, Wien 1130, Austria.
authors.forename: Ana
authors.initials: A
authors.lastname: Prinz
authors.forename: Pia Veronika
authors.initials: PV
authors.lastname: Vecsei-Marlovits
authors.forename: Dietrich
authors.initials: D
authors.lastname: Sonderhof
authors.forename: Paul
authors.initials: P
authors.lastname: Irsigler
authors.forename: Oliver
authors.initials: O
authors.lastname: Findl
authors.forename: Birgit
authors.initials: B
authors.lastname: Weingessel
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D058442:Capsule Opacification / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D053685:Laser Therapy; D053844:Lasers, Solid-State; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008866:Microsurgery; D018918:Phacoemulsification; D057852:Posterior Capsule of the Lens / Q000473:pathology* / Q000601:surgery; D011183:Postoperative Complications; D011446:Prospective Studies; D011474:Prosthesis Design; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000180:Acrylic Resins