title: Early lung retransplantation in a patient affected by cystic fibrosis correlated with donor cause of death: a case report.
abstract: The relationship between donor cause of death and lung transplantation outcomes remains unclear. We report a case of lung transplantation in a young patient affected by cystic fibrosis. Immediately after lung reperfusion a pulmonary hypertension was observed that was intractable with maximal medical therapy requiring surgical resection of the left lower lobe which became congested after a few days. The donor had died from suicidal hanging; the authors attributed the posttransplantation pulmonary hypertension which is an uncommon form of primary graft dysfunction to this cause of death. The patient was treated with early bilateral lung retransplantation which required a long, troublesome hospital stay. In conclusion, the authors warn against the use of lungs from donors who die due to hanging even when the gas exchanges were ideal.
authors.affiliation: Thoracic Surgery and Lung Transplantation Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, University of Milan, Milan, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Tosi
authors.forename: P
authors.initials: P
authors.lastname: Mendogni
authors.forename: L
authors.initials: L
authors.lastname: Rosso
authors.forename: A
authors.initials: A
authors.lastname: Palleschi
authors.forename: N
authors.initials: N
authors.lastname: Filippi
authors.forename: M
authors.initials: M
authors.lastname: Reda
authors.forename: L
authors.initials: L
authors.lastname: Santambrogio
authors.forename: M
authors.initials: M
authors.lastname: Nosotti
mesh_terms: D000293:Adolescent; D002423:Cause of Death; D003550:Cystic Fibrosis / Q000601:surgery*; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary; D016040:Lung Transplantation; D012086:Reoperation; D014019:Tissue Donors