title: Center for fetal monkey gene transfer for heart, lung, and blood diseases: an NHLBI resource for the gene therapy community.
abstract: The goals of the National Heart, Lung, and Blood Institute (NHLBI) Center for Fetal Monkey Gene Transfer for Heart, Lung, and Blood Diseases are to conduct gene transfer studies in monkeys to evaluate safety and efficiency; and to provide NHLBI-supported investigators with expertise, resources, and services to actively pursue gene transfer approaches in monkeys in their research programs. NHLBI-supported projects span investigators throughout the United States and have addressed novel approaches to gene delivery; "proof-of-principle"; assessed whether findings in small-animal models could be demonstrated in a primate species; or were conducted to enable new grant or IND submissions. The Center for Fetal Monkey Gene Transfer for Heart, Lung, and Blood Diseases successfully aids the gene therapy community in addressing regulatory barriers, and serves as an effective vehicle for advancing the field.
authors.affiliation: Center for Fetal Monkey Gene Transfer for Heart, Lung, and Blood Diseases, University of California, Davis, 95616, USA. aftarantal@primate.ucdavis.edu
authors.forename: Alice F
authors.initials: AF
authors.lastname: Tarantal
authors.forename: Sonia I
authors.initials: SI
authors.lastname: Skarlatos
mesh_terms: D000047:Academies and Institutes; D000818:Animals; D005260:Female; D018014:Gene Transfer Techniques; D015316:Genetic Therapy; D000882:Haplorhini; D006331:Heart Diseases / Q000235:genetics / Q000628:therapy; D006402:Hematologic Diseases / Q000235:genetics / Q000628:therapy; D006801:Humans; D008171:Lung Diseases / Q000235:genetics / Q000628:therapy; D008297:Male; D054555:National Heart, Lung, and Blood Institute (U.S.); D011247:Pregnancy; D014481:United States