title: Evidence-based practice: reflux in sinusitis.
abstract: It is now widely recognized that extraesophageal reflux (reflux reaching structures above the upper esophageal sphincter) has a wide range of effects on the upper aerodigestive tract, as well as the lungs. The degree to which this reflux contributes to the pathophysiology of sinusitis and other sinonasal diseases is still not completely clear, but an increasing body of literature supports a potential role.
authors.affiliation: Department of Otolaryngology, Emory University Hospital Midtown, 550 Peachtree Street, 11th floor, Atlanta, GA 30308, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Lupa
authors.forename: John M
authors.initials: JM
authors.lastname: DelGaudio
mesh_terms: D000328:Adult; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D002675:Child, Preschool; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D015331:Cohort Studies; D049631:Esophageal Sphincter, Upper / Q000294:innervation / Q000503:physiopathology; D055317:Evidence-Based Practice; D005744:Gastric Acid / Q000737:chemistry; D006801:Humans; D007249:Inflammation / Q000139:chemically induced / Q000473:pathology; D057045:Laryngopharyngeal Reflux / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology; D009297:Nasal Mucosa / Q000473:pathology; D059747:Nasal Surgical Procedures / Q000379:methods; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*; D012220:Rhinitis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D012852:Sinusitis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000897:Anti-Ulcer Agents; D054328:Proton Pump Inhibitors