title: Colorimetric protein sensing using catalytically amplified sensor arrays.
abstract: Catalytically active iron oxide nanoparticles are used as recognition elements and signal amplifiers for the array-based colorimetric sensing of proteins. Interactions between cationic monolayers on the Fe(3) O(4)  NPs and analyte proteins differentially modulates the peroxidase-like activity of Fe(3) O(4)  NPs, affording catalytically amplified colorimetric signal patterns that enable the detection and identification of proteins at 50 nM.
authors.affiliation: Department of Chemistry, University of Massachusetts, 710 North Pleasant Street, Amherst, MA 01003, USA.
authors.forename: Xiaoning
authors.initials: X
authors.lastname: Li
authors.forename: Fang
authors.initials: F
authors.lastname: Wen
authors.forename: Brian
authors.initials: B
authors.lastname: Creran
authors.forename: Youngdo
authors.initials: Y
authors.lastname: Jeong
authors.forename: Xinrong
authors.initials: X
authors.lastname: Zhang
authors.forename: Vincent M
authors.initials: VM
authors.lastname: Rotello
mesh_terms: D015374:Biosensing Techniques; D002384:Catalysis; D003124:Colorimetry / Q000379:methods; D005290:Ferric Compounds / Q000737:chemistry; D053758:Nanoparticles / Q000737:chemistry*; D009195:Peroxidase / Q000737:chemistry / Q000378:metabolism; D011506:Proteins / Q000032:analysis* / Q000737:chemistry
chemical_list: D005290:Ferric Compounds; D011506:Proteins; C000499:ferric oxide; D009195:Peroxidase