title: Renal dysfunction in heart failure.
abstract: Renal dysfunction is a common, important comorbidity in patients with both chronic and acute heart failure (HF). Chronic kidney disease and worsening renal function (WRF) are associated with worse outcomes, but our understanding of the complex bidirectional interactions between the heart and kidney remains poor. When addressing these interactions, one must consider the impact of intrinsic renal disease resulting from medical comorbidities on HF outcomes. WRF may result from any number of important processes. Understanding the role of each of these factors and their interplay are essential in understanding how to improve outcomes in patients with renal dysfunction and HF.
authors.affiliation: Emory University, Atlanta, GA 30322, USA. rtcole@emory.edu
authors.forename: Robert T
authors.initials: RT
authors.lastname: Cole
authors.forename: Amirali
authors.initials: A
authors.lastname: Masoumi
authors.forename: Filippos
authors.initials: F
authors.lastname: Triposkiadis
authors.forename: Gregory
authors.initials: G
authors.lastname: Giamouzis
authors.forename: Vasiliki
authors.initials: V
authors.lastname: Georgiopoulou
authors.forename: Andreas
authors.initials: A
authors.lastname: Kalogeropoulos
authors.forename: Javed
authors.initials: J
authors.lastname: Butler
mesh_terms: D059347:Cardio-Renal Syndrome; D004232:Diuretics / Q000627:therapeutic use; D006333:Heart Failure / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D015995:Prevalence; D011379:Prognosis; D051437:Renal Insufficiency / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology; D012307:Risk Factors
chemical_list: D004232:Diuretics