title: Successful treatment of Hurthle cell thyroid carcinoma with lung and liver metastasis using docetaxel and cisplatin.
abstract: A 36-year-old man was found to have Hurthle cell carcinoma, as diagnosed with surgical pathology after a lobectomy of the thyroid. A post-operative magnetic resonance imaging scan revealed a small mass in the lower pole of the right thyroid and a computed tomography scan showed bilateral nodules in the lungs and the neck, and multi-focal disease in the liver. He was treated with a docetaxel and cisplatin chemotherapy regimen. After six cycles of the docetaxel and cisplatin regimen, we could hardly find the lesions in the lungs and the liver, and the patient presented a complete tumor response lasting 17 months and has not shown any tumor recurrence till now. The docetaxel and cisplatin regimen may be an effective chemotherapy regimen for multi-metastases of Hurthle cell cancer.
authors.affiliation: Department of Radiation and Medical Oncology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei 430071, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.forename: Lei
authors.initials: L
authors.lastname: Zeng
authors.forename: Chen
authors.initials: C
authors.lastname: Liang
authors.forename: Hui
authors.initials: H
authors.lastname: Qiu
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhu
authors.forename: Conghua
authors.initials: C
authors.lastname: Xie
mesh_terms: D018249:Adenoma, Oxyphilic; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D000077143:Docetaxel; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008297:Male; D043823:Taxoids / Q000008:administration & dosage; D013964:Thyroid Neoplasms / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D043823:Taxoids; D000077143:Docetaxel; D002945:Cisplatin