title: Cell signals influencing hepatic fibrosis.
abstract: Liver fibrosis is the result of the entire organism responding to a chronic injury. Every cell type in the liver contributes to the fibrosis. This paper first discusses key intracellular signaling pathways that are induced during liver fibrosis. The paper then examines the effects of these signaling pathways on the major cell types in the liver. This will provide insights into the molecular pathophysiology of liver fibrosis and should identify therapeutic targets.
authors.affiliation: Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
authors.forename: Min
authors.initials: M
authors.lastname: Cong
authors.forename: Keiko
authors.initials: K
authors.lastname: Iwaisako
authors.forename: Chunyan
authors.initials: C
authors.lastname: Jiang
authors.forename: Tatiana
authors.initials: T
authors.lastname: Kisseleva