title: The yeast hypoxic responses, resources for new biotechnological opportunities.
abstract: Recent advances in the knowledge of molecular mechanisms that control the adaptation to low oxygen levels in yeast and their biotechnological applications, including bioproduct synthesis, such as ethanol, glutathione or recombinant proteins, as well as pathogenic virulence, are reviewed. Possible pathways and target genes, which might be of particular interest for the improvement of biotechnological applications, are evaluated.
authors.affiliation: Departamento de Biología Celular y Molecular, F. Ciencias, Universidad de A Coruña, Coruña, Spain. migs@udc.es
authors.forename: M Isabel
authors.initials: MI
authors.lastname: González Siso
authors.forename: Manuel
authors.initials: M
authors.lastname: Becerra
authors.forename: Mónica
authors.initials: M
authors.lastname: Lamas Maceiras
authors.forename: Angel
authors.initials: A
authors.lastname: Vizoso Vázquez
authors.forename: M Esperanza
authors.initials: ME
authors.lastname: Cerdán
mesh_terms: D000693:Anaerobiosis; D001709:Biotechnology / Q000379:methods*; D000431:Ethanol / Q000378:metabolism; D015966:Gene Expression Regulation, Fungal; D005978:Glutathione / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism*; D011994:Recombinant Proteins / Q000378:metabolism; D013312:Stress, Physiological; D037521:Virulence Factors / Q000378:metabolism; D015003:Yeasts / Q000378:metabolism / Q000502:physiology*
chemical_list: D011994:Recombinant Proteins; D037521:Virulence Factors; D000431:Ethanol; D005978:Glutathione; D010100:Oxygen