title: Cerebral sinovenous thrombosis associated with mastoiditis due to recurrent otitis media.
abstract: Cerebral sinovenous thrombosis (CSVT) in childhood is a rare reported. In this era of widespread antibiotic use for acute otitis media, the incidence of otogenic CSVT has markedly declined but has not been completely prevented. The current therapies for CSVT include anticoagulation, thrombolysis, hydration, surgery, and supportive care that were based on adult studies, pediatric case studies, and expert opinion. We describe the case of a 3-year-old boy who presented with manifestations of CSVT associated with mastoiditis secondary to otitis media. He completed a 3-month course of combination antibiotic and anticoagulation therapy; the CSVT was recanalized, and the mastoiditis had partially improved.
authors.affiliation: Department of Pharmacy, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.
authors.forename: Pi-Lien
authors.initials: PL
authors.lastname: Hung
authors.forename: Pei-Chin
authors.initials: PC
authors.lastname: Lin
authors.forename: Pi-Lai
authors.initials: PL
authors.lastname: Tseng
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008417:Mastoiditis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D010033:Otitis Media / Q000150:complications* / Q000188:drug therapy; D012008:Recurrence; D012851:Sinus Thrombosis, Intracranial / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000925:Anticoagulants