title: Interaction of colloidal zinc oxide nanoparticles with bovine serum albumin and its adsorption isotherms and kinetics.
abstract: Zinc oxide nanoparticles (ZnO NPs) are widely used in medical, industrial and household application owing to excellent antimicrobial property. The biocompatibility of nanoparticles is important for specific biomedical applications. The aim of this study was to stabilize and biofunctionalize ZnO NPs using bovine serum albumin (BSA). Here we have investigated the adsorption behavior of BSA onto ZnO NPs in aqueous solutions. Influence of pH on the adsorption of BSA onto ZnO NPs was also investigated. The study suggests that the electrostatic force of attraction favors the adsorption of BSA onto ZnO NPs. The adsorption data fitted well by Freundlich isotherm compared to Langmuir isotherm. The kinetics of adsorption fitted best to pseudo-second-order.
authors.affiliation: Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam 638 401, Erode District, Tamil Nadu, India.
authors.forename: Neethu P
authors.initials: NP
authors.lastname: Sasidharan
authors.forename: Preethy
authors.initials: P
authors.lastname: Chandran
authors.forename: S
authors.initials: S
authors.lastname: Sudheer Khan
mesh_terms: D000327:Adsorption; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D015227:Lipid Peroxidation; D008962:Models, Theoretical; D053758:Nanoparticles / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D015034:Zinc Oxide / Q000737:chemistry*
chemical_list: D012710:Serum Albumin, Bovine; D015034:Zinc Oxide