title: From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior.
abstract: Over the past two centuries, prevalent models of energy and glucose homeostasis have emerged from careful anatomical descriptions in tandem with an understanding of cellular physiology. More recent technological advances have culminated in the identification of peripheral and central factors that influence neural circuits regulating metabolism. This Review highlights contributions to our understanding of peripheral and central factors regulating food intake and energy expenditure.
authors.affiliation: Department of Internal Medicine, Division of Hypothalamic Research, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA. kevin.williams@utsouthwestern.edu
authors.forename: Kevin W
authors.initials: KW
authors.lastname: Williams
authors.forename: Joel K
authors.initials: JK
authors.lastname: Elmquist
mesh_terms: D000818:Animals; D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology*; D002766:Cholecystokinin; D004435:Eating / Q000502:physiology; D004734:Energy Metabolism / Q000502:physiology*; D005247:Feeding Behavior / Q000502:physiology*; D054439:Ghrelin / Q000502:physiology; D052216:Glucagon-Like Peptide 1 / Q000502:physiology; D006801:Humans; D007328:Insulin / Q000494:pharmacology; D020738:Leptin / Q000502:physiology; D053486:Melanocortins / Q000502:physiology; D008959:Models, Neurological; D009434:Neural Pathways / Q000033:anatomy & histology / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology
chemical_list: D054439:Ghrelin; D007328:Insulin; D020738:Leptin; D053486:Melanocortins; D052216:Glucagon-Like Peptide 1; D002766:Cholecystokinin