title: Association between pre-eclampsia and inherited thrombophilias.
abstract: OBJECTIVE
  The aim was to determine whether inherited thrombophilia increases the risk of pre-eclampsia (PE) or interferes with its clinical course.
  
  
  METHODS
  We included 50 patients with severe PE and 50 healthy pregnant women. Patients were evaluated for inherited thrombophilia.
  
  
  RESULTS
  Fourteen patients in the study group was factor V Leiden (FVL) carrier while it was 12% in the control group. In women with PE, FVL and other inherited thrombophilic factors were not more prevalent than in the controls.
  
  
  CONCLUSIONS
  The present study failed to demonstrate an association between the inherited thrombophilias and PE.
authors.affiliation: Zekai Tahir Burak Women Health Research and Education Hospital, Ankara, Turkey. deveer3@hotmail.com
authors.forename: Rüya
authors.initials: R
authors.lastname: Deveer
authors.forename: Yaprak
authors.initials: Y
authors.lastname: Engin-Ustun
authors.forename: Eren
authors.initials: E
authors.lastname: Akbaba
authors.forename: Beril
authors.initials: B
authors.lastname: Halisdemir
authors.forename: Esra
authors.initials: E
authors.lastname: Cakar
authors.forename: Nuri
authors.initials: N
authors.lastname: Danisman
authors.forename: Leyla
authors.initials: L
authors.lastname: Mollamahmutoglu
authors.forename: Ahmet
authors.initials: A
authors.lastname: Yesilyurt
authors.forename: Zuhal
authors.initials: Z
authors.lastname: Candemir
mesh_terms: D000328:Adult; D001724:Birth Weight; D002353:Carrier State; D003430:Cross-Sectional Studies; D005165:Factor V / Q000235:genetics; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood / Q000175:diagnosis / Q000235:genetics*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000175:diagnosis / Q000235:genetics*; D012307:Risk Factors; D019851:Thrombophilia / Q000097:blood / Q000175:diagnosis / Q000235:genetics*
chemical_list: C095381:factor V Leiden; D005165:Factor V