title: Clinical predictors of outcome in MPN.
abstract: Myeloproliferative neoplasms include 3 diseases: polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). PV and ET are dominated by a high risk of thrombosis and a late risk of clonal evolution into secondary MF and acute myeloid leukemia. Patients with PMF may encounter many complications associated with disease progression or with PMF evolution. This article defines factors that determine prognosis in these 3 diseases.
authors.affiliation: Division of Hematology, Department of Internal Medicine, Ospedale di Circolo e Fondazione Macchi, Viale Borri 57, 21100 Varese, Italy. francesco.passamonti@ospedale.varese.it
authors.forename: Francesco
authors.initials: F
authors.lastname: Passamonti
authors.forename: Margherita
authors.initials: M
authors.lastname: Maffioli
authors.forename: Michele
authors.initials: M
authors.lastname: Merli
authors.forename: Andrea
authors.initials: A
authors.lastname: Ferrario
authors.forename: Domenica
authors.initials: D
authors.lastname: Caramazza
mesh_terms: D006801:Humans; D011087:Polycythemia Vera / Q000209:etiology / Q000401:mortality* / Q000628:therapy; D055728:Primary Myelofibrosis / Q000209:etiology / Q000401:mortality* / Q000628:therapy; D011379:Prognosis; D012307:Risk Factors; D015996:Survival Rate; D013920:Thrombocythemia, Essential / Q000209:etiology / Q000401:mortality* / Q000628:therapy