title: A reaction-based sensing scheme for gold species: introduction of a (2-ethynyl)benzoate reactive moiety.
abstract: To alleviate side reactions identified in an N-propargyl-rhodamine lactam sensing system, we devised the novel reaction-based sensing scheme for gold species based on the alkynophilicity. A fluorescein (2-ethynyl)benzoate underwent Au(III)-promoted ester hydrolysis selectively over other metal ions with high sensitivity, which accompanies a turn-on fluorescence change in pH 7.4 HEPES buffer. The work offers a versatile reactive moiety for the development of gold probes with improved sensing properties.
authors.affiliation: Department of Chemistry and Center for Electro-Photo Behaviors in Advanced Molecular Systems, Pohang University of Science and Technology, San 31, Hyoja-dong, Pohang, 790-784, Republic of Korea.
authors.forename: Hyewon
authors.initials: H
authors.lastname: Seo
authors.forename: Mi Eun
authors.initials: ME
authors.lastname: Jun
authors.forename: Olga A
authors.initials: OA
authors.lastname: Egorova
authors.forename: Kyung-Ha
authors.initials: KH
authors.lastname: Lee
authors.forename: Kyong-Tai
authors.initials: KT
authors.lastname: Kim
authors.forename: Kyo Han
authors.initials: KH
authors.lastname: Ahn
mesh_terms: D001565:Benzoates / Q000737:chemistry*; D019793:Fluorescein / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure
chemical_list: D001565:Benzoates; D006046:Gold; D019793:Fluorescein