title: The outcomes of navigation-assisted bone tumour surgery: minimum three-year follow-up.
abstract: We evaluated the oncological and functional outcome   of 18 patients, whose malignant bone tumours were excised with the   assistance of navigation, and who were followed up for more than   three years. There were 11 men and seven women, with a mean age   of 31.8 years (10 to 57). There were ten operations on the pelvic   ring and eight joint-preserving limb salvage procedures. The resection   margins were free of tumour in all specimens. The tumours, which   were stage IIB in all patients, included osteosarcoma, high-grade   chondrosarcoma, Ewing's sarcoma, malignant fibrous histiocytoma   of bone, and adamantinoma. The overall three-year survival rate   of the 18 patients was 88.9% (95% confidence interval (CI) 75.4   to 100). The three-year survival rate of the patients with pelvic malignancy   was 80.0% (95% CI 55.3 to 100), and of the patients with metaphyseal   malignancy was 100%. The event-free survival was 66.7% (95% CI 44.9   to 88.5). Local recurrence occurred in two patients, both of whom   had a pelvic malignancy. The mean Musculoskeletal Tumor Society   functional score was 26.9 points at a mean follow-up of 48.2 months   (22 to 79). We suggest that navigation can be helpful during surgery for   musculoskeletal tumours; it can maximise the accuracy of resection   and minimise the unnecessary sacrifice of normal tissue by providing   precise intra-operative three-dimensional radiological information.
authors.affiliation: Seoul National University College of Medicine, Department of Orthopedic Surgery, Seoul National University Bundang Hospital, 82 Gumi-Ro 173 Beon-Gil, Bundang-Gu, Seongnam-Si, Gyeonggi-Do, Korea.
authors.forename: H S
authors.initials: HS
authors.lastname: Cho
authors.forename: J H
authors.initials: JH
authors.lastname: Oh
authors.forename: I
authors.initials: I
authors.lastname: Han
authors.forename: H-S
authors.initials: HS
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000601:surgery*; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013238:Stereotaxic Techniques; D016019:Survival Analysis; D016896:Treatment Outcome; D055815:Young Adult