title: Genetic profiling of BRAF inhibitor-induced keratoacanthomas reveals no induction of MAP kinase pathway expression.
authors.affiliation: Division of Dermatology, UCLA Medical Center, Los Angeles, California, USA. Electronic address: rkulkarn@ucla.edu.
authors.forename: Rajan P
authors.initials: RP
authors.lastname: Kulkarni
authors.affiliation: Department of Translational Immunology, Dirks/Dougherty Laboratory for Cancer Research, John Wayne Cancer Institute, Santa Monica, California, USA.
authors.forename: Seema
authors.initials: S
authors.lastname: Plaisier
authors.affiliation: Department of Pathology, UCLA Medical Center, Los Angeles, California, USA.
authors.forename: Seong H
authors.initials: SH
authors.lastname: Ra
authors.affiliation: Department of Pathology, UCLA Medical Center, Los Angeles, California, USA.
authors.forename: Xinmin
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Translational Immunology, Dirks/Dougherty Laboratory for Cancer Research, John Wayne Cancer Institute, Santa Monica, California, USA.
authors.forename: Delphine J
authors.initials: DJ
authors.lastname: Lee
authors.affiliation: Department of Pathology, UCLA Medical Center, Los Angeles, California, USA.
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Hillman
authors.affiliation: Department of Pathology, UCLA Medical Center, Los Angeles, California, USA.
authors.forename: Scott W
authors.initials: SW
authors.lastname: Binder
mesh_terms: D001706:Biopsy; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation / Q000187:drug effects; D006801:Humans; D007211:Indoles / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use; D007636:Keratoacanthoma / Q000139:chemically induced* / Q000235:genetics / Q000378:metabolism*; D008545:Melanoma / Q000188:drug therapy; D020929:Mitogen-Activated Protein Kinase Kinases / Q000235:genetics / Q000378:metabolism*; D048493:Proto-Oncogene Proteins B-raf / Q000037:antagonists & inhibitors*; D012189:Retrospective Studies; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology*; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000139:chemically induced / Q000235:genetics / Q000378:metabolism; D012878:Skin Neoplasms / Q000188:drug therapy; D013449:Sulfonamides / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use; D000077484:Vemurafenib
chemical_list: D007211:Indoles; D013449:Sulfonamides; D000077484:Vemurafenib; C482119:BRAF protein, human; D048493:Proto-Oncogene Proteins B-raf; D020929:Mitogen-Activated Protein Kinase Kinases