title: Development of an AMR-ACB array for gastrointestinal motility studies.
abstract: The association between anisotropic magnetoresistive (AMR) sensor and AC biosusceptometry (ACB) to evaluate gastrointestinal motility is presented. The AMR-ACB system was successfully characterized in a bench-top study, and in vivo results were compared with those obtained by means of simultaneous manometry. Both AMR-ACB and manometry techniques presented high temporal cross correlation between the two periodicals signals . The contraction frequencies using AMR-ACB were 73.9 ± 7.6 mHz and using manometry were 73.8 ± 7.9 mHz during the baseline . The amplitude of contraction using AMR-ACB was 396 ± 108 μT·s and using manometry were 540 ± 198 mmHg·s during the baseline. The amplitudes of signals for AMR-ACB and manometric recordings were similarly increased to 86.4% and 89.3% by neostigmine, and also decreased to 27.2% and 21.4% by hyoscine butylbromide in all animals, respectively. The AMR-ACB array is nonexpensive, portable, and has high-spatiotemporal resolution to provide helpful information about gastrointestinal tract.
authors.affiliation: Universidade Estadual Paulista, Botucatu, SP, Brazil. fcpaixao@ibb.unesp.br
authors.forename: Fabiano C
authors.initials: FC
authors.lastname: Paixão
authors.forename: Luciana A
authors.initials: LA
authors.lastname: Corá
authors.forename: Madileine F
authors.initials: MF
authors.lastname: Américo
authors.forename: Ricardo Brandt
authors.initials: RB
authors.lastname: de Oliveira
authors.forename: Oswaldo
authors.initials: O
authors.lastname: Baffa
authors.forename: José Ricardo A
authors.initials: JR
authors.lastname: Miranda
mesh_terms: D000818:Animals; D016880:Anisotropy; D004285:Dogs; D004574:Electromagnetic Fields; D004867:Equipment Design; D005769:Gastrointestinal Motility / Q000502:physiology*; D008365:Manometry / Q000295:instrumentation / Q000379:methods; D008962:Models, Theoretical; D008991:Monitoring, Physiologic / Q000295:instrumentation* / Q000379:methods*; D012815:Signal Processing, Computer-Assisted