title: Different ophthalmologic manifestations of sarcoidosis.
abstract: OBJECTIVE
  Sarcoidosis can manifest with different ocular findings. Three different cases have been presented, each of which showed different ocular problems. The literature has also been reviewed as to find out other eye signs and treatment strategies of the disease. The diagnosis may be difficult and the treatment may include combination of different immunosuppressors.
  
  
  RESULTS
  Recent findings include a genetic basis, and certain human leukocyte antigens may affect the course of the disease. Sarcoidosis can influence the eye and the optic nerves in the beginning, and biopsy of the involved tissue may be necessary for the diagnosis. Laboratory investigation may be unyielding. Once the diagnosis is made, steroids are generally started. Other than the classical corticosteroid treatment, other immunosuppressive agents show promise in the atypical cases.
  
  
  CONCLUSIONS
  Our cases show different manifestations of the disease like bilateral optic neuropathy, Horner's syndrome, pars planitis, and anterior and posterior uveitis. Patients recovered with steroid treatment, but especially in young patients other agents like methotrexate were needed because of the sideeffects of steroids.
authors.affiliation: Dunya Goz Hospital, Istanbul, Turkey. kayabasi@yahoo.com
authors.forename: Kayabasi A
authors.initials: KA
authors.lastname: Umur
authors.forename: Bavbek
authors.initials: B
authors.lastname: Tayfun
authors.forename: Onultan
authors.initials: O
authors.lastname: Oguzhan
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D006732:Horner Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008727:Methotrexate / Q000627:therapeutic use; D009901:Optic Nerve Diseases / Q000175:diagnosis* / Q000188:drug therapy; D015868:Pars Planitis / Q000175:diagnosis* / Q000188:drug therapy; D012507:Sarcoidosis / Q000175:diagnosis* / Q000188:drug therapy; D015866:Uveitis, Posterior / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D007166:Immunosuppressive Agents; D008727:Methotrexate