title: Post-prostate biopsy infection with Escherichia coli ST131 leading to epididymo-orchitis and meningitis caused by Gram-negative bacilli.
abstract: A 57-year-old man who had recently undergone a transrectal prostate biopsy for a rising prostate-specific antigen level developed postbiopsy necrotizing epididymo-orchitis (requiring orchiectomy) and then Gram-negative meningitis, despite fluoroquinolone administration for periprocedural prophylaxis and subsequent therapy. The causative organism proved to be a fluoroquinolone-resistant Escherichia coli strain from sequence type ST131.
authors.affiliation: Sunwest Infusion and Infectious Disease Specialists, Goodyear, Arizona, USA.
authors.forename: Aris
authors.initials: A
authors.lastname: Assimacopoulos
authors.forename: Brian
authors.initials: B
authors.lastname: Johnston
authors.forename: Connie
authors.initials: C
authors.lastname: Clabots
authors.forename: James R
authors.initials: JR
authors.lastname: Johnson
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology; D001706:Biopsy / Q000009:adverse effects*; D016000:Cluster Analysis; D024881:Drug Resistance, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D004823:Epididymitis / Q000150:complications* / Q000382:microbiology; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000175:diagnosis*; D024841:Fluoroquinolones / Q000008:administration & dosage / Q000494:pharmacology; D005838:Genotype; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000150:complications* / Q000382:microbiology; D008875:Middle Aged; D058889:Molecular Typing; D009920:Orchitis / Q000150:complications* / Q000382:microbiology; D011471:Prostatic Neoplasms / Q000175:diagnosis*
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones