title: Early onset sepsis in very low birth weight newborn infants.
abstract: Early onset sepsis (EOS) is a severe problem affecting very low birth weight (VLBW) infants and is associated with a threefold increased risk of mortality. Although advances in perinatal care have led to improved survival of VLBW infants over recent decades, survival without major neonatal morbidity has not increased. The authors reviewed the current literature on EOS, focusing on the peculiarities concerning risk factors, etiology, diagnosis, treatment and outcome in very low birth weight infants, and on the recent advances in the management of this condition.
authors.affiliation: Paediatrics and Infant Neuropsychiatry Department, Sapienza University of Rome, Rome, Italy.
authors.forename: Valentina
authors.initials: V
authors.lastname: Pisani
authors.forename: Bianca
authors.initials: B
authors.lastname: Bizzarri
authors.forename: Veronica
authors.initials: V
authors.lastname: Cardi
authors.forename: Roberto
authors.initials: R
authors.lastname: Pedicino
authors.forename: Fabio
authors.initials: F
authors.lastname: Natale
authors.forename: Ilaria
authors.initials: I
authors.lastname: Stolfi
authors.forename: Antonella
authors.initials: A
authors.lastname: Castronovo
authors.forename: Mario
authors.initials: M
authors.lastname: De Curtis
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D019102:Infant, Very Low Birth Weight; D012307:Risk Factors; D018805:Sepsis / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D016896:Treatment Outcome