title: Spontaneously healed asymptomatic pulmonary tuberculosis: prevalence of airflow obstruction, and correlation between high-resolution CT findings and pulmonary function tests.
abstract: OBJECTIVE
  We investigated the relationships between spontaneously healed asymptomatic pulmonary tuberculosis (SHAPTB), airflow obstruction (AFO), and high-resolution computed tomography (HRCT) findings.
  
  
  METHODS
  We selected 82 participants with SHAPTB diagnosed by interferon-γ release assay and 8044 with normal chest radiographs (CXR). We applied a CT scoring system for the extent of tuberculous sequelae to correlate the HRCT findings with pulmonary function test. We compared the AFO prevalence between subjects with and without SHAPTB.
  
  
  RESULTS
  The subjects with SHAPTB diagnosed by interferon-γ release assay had a significantly higher prevalence of AFO (13.4% [11/82]) than those with normal CXR (7.4% [595/8044]). The important HRCT findings that correlated with AFO were the number of lung segments with TB sequelae and the CT score for emphysema.
  
  
  CONCLUSIONS
  The subjects with SHAPTB had a higher AFO prevalence than those with normal CXR, and the important HRCT findings correlated with AFO were the extent of tuberculous sequelae and emphysema.
authors.affiliation: Department of Radiology, Korea University Hospital, Seoul, Korea. cornerstonelee@gmail.com
authors.forename: Ki Yeol
authors.initials: KY
authors.lastname: Lee
authors.forename: Chol
authors.initials: C
authors.lastname: Shin
authors.forename: Jung Bok
authors.initials: JB
authors.lastname: Lee
authors.forename: Eun-Young
authors.initials: EY
authors.lastname: Kang
authors.forename: Yu Whan
authors.initials: YW
authors.lastname: Oh
authors.forename: Bo Kyung
authors.initials: BK
authors.lastname: Je
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Choo
authors.forename: Dae Wui
authors.initials: DW
authors.lastname: Yoon
authors.forename: Pyong-Kon
authors.initials: PK
authors.lastname: Cho
mesh_terms: D000328:Adult; D000368:Aged; D000402:Airway Obstruction / Q000000981:diagnostic imaging* / Q000453:epidemiology* / Q000503:physiopathology*; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D059425:Interferon-gamma Release Tests; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D011857:Radiographic Image Interpretation, Computer-Assisted; D013902:Radiography, Thoracic; D012075:Remission, Spontaneous; D012129:Respiratory Function Tests; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging* / Q000503:physiopathology*