title: The use of deep frozen and irradiated bone allografts in the reconstruction of tibial plateau fractures.
abstract: To investigate the clinical behavior of deep frozen and irradiated bone allografts in the treatment of depressed tibial plateau fractures. Twenty-two patients with a tibial plateau fracture were treated with cancellous bone allografts. The bone allograft preparation process included fresh-freezing at -70 °C for 4 weeks and gamma-irradiation at 25 kGy. All of the patients were followed for 1-2 years. The clinical effects were assessed using the Rasmussen score for tibial head fractures and X-rays. Postoperatively, the average excellent and fair Rasmussen scores were 88.9%. Only one patient developed an infection, with no integration between allograft and recipient bone observed. All of the other bone allografts were incorporated successfully, and no osteoporosis or sclerosis was observed. The frozen and gamma-irradiated bone allograft is a good alternative in the treatment of tibial plateau fractures, which we have shown can integrate with the surrounding host bone.
authors.affiliation: Department of Orthopaedics, The First Hospital of Jilin University, Changchun, 130021, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Feng
authors.forename: Li
authors.initials: L
authors.lastname: Fu
authors.forename: Jianguo
authors.initials: J
authors.lastname: Liu
authors.forename: Dongsong
authors.initials: D
authors.lastname: Li
authors.forename: Xin
authors.initials: X
authors.lastname: Qi
mesh_terms: D000328:Adult; D064591:Allografts / Q000528:radiation effects*; D001860:Bone Plates; D016025:Bone Transplantation; D003710:Demography; D005260:Female; D005500:Follow-Up Studies; D005592:Fracture Fixation; D017102:Fracture Healing / Q000528:radiation effects; D005615:Freezing; D005720:Gamma Rays; D006801:Humans; D008297:Male; D011859:Radiography; D019651:Plastic Surgery Procedures; D013978:Tibial Fractures / Q000000981:diagnostic imaging / Q000601:surgery*; D016896:Treatment Outcome