title: Secondary caries inhibition promoted by adhesive systems and bleaching agents with fluoride.
abstract: OBJECTIVE
  To evaluate the initial caries development at adhesive/enamel interface after 10% carbamide peroxide bleaching (CP) with or without fluoride (F) under dynamic pH-cycling.
  
  
  METHODS
  Standard cavities were prepared on the bucal surface of 60 bovine incisors, which were restored with two fluoride-containing adhesives: Optibond FL (FL) and Optibond Solo Plus (SP). The restored teeth were submitted to thermal cycling process in order to age the adhesive/enamel interface. Both SP and FL adhesive-restored teeth were divided into groups (n= 10) and bleached with 10% CP (CP) and 10% CP + F (CPF) or remained unbleached (Control). Bleaching was performed for 14 days simultaneously with pH-cycling. The specimens were prepared for cross-section microhardness evaluation and polarized light microscopy analysis to evaluate caries lesions at different depths around the bonded interface.
  
  
  RESULTS
  Group FL (not bleached) presented the lowest mineral loss rate among groups, but secondary caries formation was observed for all groups around the bonded interface. An inhibition zone was observed for all groups, with caries lesion detected at 5 microm from the cavity wall.
authors.affiliation: Department of Dentistry, University of Taubaté, R. Expedicionário Ernesto Pereira, 110, Taubaté - SP 12020-330 Brazil. vcavalli@yahoo.com
authors.forename: Vanessa
authors.initials: V
authors.lastname: Cavalli
authors.forename: Camila de Aquino
authors.initials: Cde A
authors.lastname: Cardoso
authors.forename: Francine de Almeida
authors.initials: Fde A
authors.lastname: Zandonadi
authors.forename: Priscila Christiane Suzy
authors.initials: PC
authors.lastname: Liporoni
authors.forename: Sandrine Bittencourt
authors.initials: SB
authors.lastname: Berger
authors.forename: Marcelo
authors.initials: M
authors.lastname: Giannini
mesh_terms: D000818:Animals; D000077463:Carbamide Peroxide; D002327:Cariostatic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002417:Cattle; D003731:Dental Caries / Q000517:prevention & control*; D003732:Dental Caries Activity Tests; D003743:Dental Enamel / Q000187:drug effects / Q000473:pathology; D003793:Dental Restoration, Permanent / Q000379:methods; D003799:Dental Stress Analysis; D005459:Fluorides / Q000008:administration & dosage / Q000627:therapeutic use*; D006244:Hardness / Q000187:drug effects; D010545:Peroxides / Q000008:administration & dosage / Q000627:therapeutic use; D019279:Resin Cements / Q000737:chemistry / Q000627:therapeutic use*; D055502:Secondary Prevention; D058205:Tooth Bleaching Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D014508:Urea / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D002327:Cariostatic Agents; C469607:OptiBond FL; C451600:OptiBond Solo Plus; D010545:Peroxides; D019279:Resin Cements; D058205:Tooth Bleaching Agents; D000077463:Carbamide Peroxide; D014508:Urea; D005459:Fluorides