title: One-step hydrothermal synthesis of carboxyl-functionalized upconversion phosphors for bioapplications.
abstract: In this paper, we report a facile one-step hydrothermal method to synthesize phase-, size-, and shape-controlled carboxyl-functionalized rare-earth fluorescence upconversion phosphors by using a small-molecule binary acid, such as malonic acid, oxalic acid, succinic acid, or tartaric acid as capping agent. The crystals, from nano- to microstructures with diverse shapes that include nanospheres, microrods, hexagonal prisms, microtubes, microdisks, polygonal columns, and hexagonal tablets, can be obtained with different reaction times, reaction temperatures, molar ratios of capping agent to sodium hydroxide, and by varying the binary acids. Fourier transform infrared, thermogravimetric analysis, and upconversion luminescence spectra measurements indicate that the synthesized NaYF(4):Yb/Er products with hydrophilic carboxyl-functionalized surface offer efficient upconversion luminescent performance. Furthermore, the antibody/secondary antibody conjugation can be realized by the carboxyl-functionalized surfaces of the upconversion phosphors, thus indicating the potential bioapplications of these kinds of materials.
authors.affiliation: Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, PR China.
authors.forename: Jianping
authors.initials: J
authors.lastname: Yang
authors.forename: Dengke
authors.initials: D
authors.lastname: Shen
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Yin
authors.initials: Y
authors.lastname: Fang
authors.forename: Yong
authors.initials: Y
authors.lastname: Wei
authors.forename: Chi
authors.initials: C
authors.lastname: Yao
authors.forename: Bo
authors.initials: B
authors.lastname: Tu
authors.forename: Fan
authors.initials: F
authors.lastname: Zhang
authors.forename: Dongyuan
authors.initials: D
authors.lastname: Zhao
mesh_terms: D000906:Antibodies / Q000276:immunology; D003998:Dicarboxylic Acids / Q000737:chemistry*; D007118:Immunoassay; D008163:Luminescent Measurements; D008314:Malonates / Q000737:chemistry; D008674:Metals, Rare Earth / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry; D019815:Oxalic Acid / Q000737:chemistry; D010316:Particle Size; D019802:Succinic Acid / Q000737:chemistry; D013644:Tartrates / Q000737:chemistry
chemical_list: D000906:Antibodies; D003998:Dicarboxylic Acids; D008314:Malonates; D008674:Metals, Rare Earth; D013644:Tartrates; D019815:Oxalic Acid; C030290:malonic acid; D019802:Succinic Acid; C029768:tartaric acid