title: Correlation between lens thickness and central anterior chamber depth.
abstract: OBJECTIVE
  To investigate gender differences in lens thickness (LT) and central anterior chamber depth (ACD) in normal subjects, and to assess age associated changes in these measures.
  
  
  METHODS
  The anterior chamber depth (ACD), and lens thickness (LT), of 150 normal subjects (150 eyes) was measured by anterior segment optical coherence tomography (AS- OCT). Gender differences were assessed by independent t-test, and correlation analysis was used to examine the effect of age.
  
  
  RESULTS
  The mean values of ACD and LT were 0.69±0.32 mm and 4.85±0.43 mm, respectively. Women had a significantly lower Mean ACD as compared to men (2.56±0.33mm vs 2.85±0.29 mm; P﹤0.05). No statistically significant difference was found in LT between male and female subjects (P＞0.05). Correlation analysis findings suggest that LT increases with age (r =0.83, P﹤0.05), and that ACD decreases with age (r=- 0.57, P﹤0.05). After controlling for LT, no significant correlation was observed between age and ACD (P＞0.05).
  
  
  CONCLUSIONS
  The ACD of female subjects was, on average, shallower than that of their male counterparts. Aging was associated with increasing LT, and the observed narrowing of ACD with age, might be partially mediated by the increasing LT.
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
authors.forename: Yangfa
authors.initials: Y
authors.lastname: Zeng
authors.forename: Xing
authors.initials: X
authors.lastname: Liu
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Yimin
authors.initials: Y
authors.lastname: Zhong
authors.forename: Jingjing
authors.initials: J
authors.lastname: Huang
authors.forename: Mingguang
authors.initials: M
authors.lastname: He
mesh_terms: D000328:Adult; D000375:Aging; D000867:Anterior Chamber / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000033:anatomy & histology*; D008297:Male; D009929:Organ Size; D012737:Sex Factors; D041623:Tomography, Optical Coherence