title: [Phenolic acid derivatives from Alchornea trewioides].
abstract: To study the chemical constituents of Alchornea trewioides, silica gel column chromatography, Sephadex LH-20, reverse phase ODS column chromatography, MCI and semi-preparative HPLC were used to separate the 95% EtOH extract of the root of Alchornea trewioides. The structures were elucidated on the basis of spectroscopic studies including ESI-TOF-MS, 1H NMR, 13C NMR, HSQC and HMBC. Eight phenolic acids were obtained and identified as 1-O-galloyl-6-O-vanilloyl-beta-glucose (1), gallic acid (2), ethyl gallate (3), syringic acid (4), glucosyringic acid (5), erigeside C (6), 3, 4-dimethoxyphenyl-(6'-O-alpha-L-rhamnosyl)-beta-D-glucopyranoside (7) and 3, 4, 5-trimethoxyphenyl-(6'-O-galloyl)-O-beta-D-glucopyranoside (8). Among them, compound 1 is a new compound, compounds 4-8 are isolated from the genus Alchornea for the first time, and the others are isolated from the plant for the first time.
authors.affiliation: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University Beijing 100191, China.
authors.forename: Ri-Dong
authors.initials: RD
authors.lastname: Qin
authors.forename: Wei
authors.initials: W
authors.lastname: Cheng
authors.forename: Qing-Ying
authors.initials: QY
authors.lastname: Zhang
authors.forename: Hong
authors.initials: H
authors.lastname: Liang
mesh_terms: D001565:Benzoates / Q000737:chemistry / Q000302:isolation & purification; D019665:Euphorbiaceae / Q000737:chemistry*; D005707:Gallic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D005947:Glucose / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D062385:Hydroxybenzoates / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: C583519:1-O-galloyl-6-O-vanilloyl-beta-glucose; D001565:Benzoates; D005960:Glucosides; D062385:Hydroxybenzoates; D010636:Phenols; C578909:erigeside C; C048734:ethyl gallate; C092651:glucosyringic acid; D005707:Gallic Acid; C001945:syringic acid; C017616:phenolic acid; D005947:Glucose