title: [Chemical constituents of Trichosanthes kirilowii Maxim].
abstract: To study the chemical constituents of Trichosanthes kirilowii Maxim., chromatographic methods such as D101 macroporous resin, silica gel column chromatographic technology, Sephadex LH-20, octadecylsilyl (ODS) column chromatographic technique and preparative HPLC were used and nine compounds were isolated from a 95% (v/v) ethanol extract of the plant. By using spectroscopic techniques including 1H NMR, 13C NMR, 1H-1H COSY, HSQC and HMBC, these compounds were identified as 5-ethoxymethyl-1-carboxyl propyl-1H-pyrrole-2-carbaldehyde (1), 5-hydroxymethyl-2-furfural (2), chrysoeriol (3), 4'-hydroxyscutellarin (4), vanillic acid (5), alpha-spinasterol (6), beta-D-glucopyranosyl-a-spinasterol (7), stigmast-7-en-3beta-ol (8), and adenosine (9), separately. Among them, compound 1 is a new compound, and compounds 3, 4 and 5 are isolated from the genus Trichosanthes kirilowii Maxim. for the first time.
authors.affiliation: Tianjin University of Traditional Chinese Medicine, Tianjin Key Laboratory of Modern Chinese Medicine, Tianjin Key Laboratory of Traditional Chinese Medicine Chemistry and Analysis, Tianjin 300193, China.
authors.forename: Xiao-Ye
authors.initials: XY
authors.lastname: Sun
authors.forename: Hong-Hua
authors.initials: HH
authors.lastname: Wu
authors.forename: Ai-Zhen
authors.initials: AZ
authors.lastname: Fu
authors.forename: Peng
authors.initials: P
authors.lastname: Zhang
mesh_terms: D047310:Apigenin / Q000737:chemistry / Q000302:isolation & purification; D047309:Flavones / Q000737:chemistry / Q000302:isolation & purification; D005638:Fruit / Q000737:chemistry; D005965:Glucuronates / Q000737:chemistry / Q000302:isolation & purification; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry / Q000302:isolation & purification*; D029778:Trichosanthes / Q000737:chemistry*; D014641:Vanillic Acid / Q000737:chemistry / Q000302:isolation & purification
chemical_list: C583502:4'-hydroxyscutellarin; C583501:5-ethoxymethyl-1-carboxyl propyl-1H-pyrrole-2-carbaldehyde; D047309:Flavones; D005965:Glucuronates; D011758:Pyrroles; D047310:Apigenin; D014641:Vanillic Acid; C007054:chrysoeriol