title: Speeding up a bidirectional DNA walking device.
abstract: A strategy to speed up DNA walking devices through the use of DNA catalysts has been developed. The DNA walker is designed to move on a three-foothold molecular track with the assistance of fuel strands. The movement can be accelerated in the presence of catalysts. The motor could be halted at a desired location by a simple control, and the locomotion is about 1 order of magnitude faster than previous hybridization-based walker. Additionally, one branch of the walker can be designed to capture and transfer protein or some other inorganic molecules along the designed track with easy control, which makes our engineered DNA system more versatile.
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.
authors.forename: Chunyan
authors.initials: C
authors.lastname: Wang
authors.forename: Yu
authors.initials: Y
authors.lastname: Tao
authors.forename: Guangtao
authors.initials: G
authors.lastname: Song
authors.forename: Jinsong
authors.initials: J
authors.lastname: Ren
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Qu
mesh_terms: D002384:Catalysis; D004247:DNA / Q000737:chemistry*; D004586:Electrophoresis; D005453:Fluorescence; D009693:Nucleic Acid Hybridization; D009841:Oligonucleotides / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013997:Time Factors
chemical_list: D009841:Oligonucleotides; D004247:DNA