title: Presumed hydrogen sulfide-mediated neurotoxicity after streptococcus anginosus group meningitis.
abstract: Hydrogen sulfide is an environmental toxicant and gaseous neurotransmitter. It is produced enterically by sulfur-reducing bacteria and invasive pathogens including Streptococcus anginosus group, Salmonella and Citrobacter. We describe putative focal hydrogen sulfide neurotoxicity after Streptococcus constellatus meningitis, treated with adjunctive sodium nitrite and hyperbaric oxygen therapy.
authors.affiliation: Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53201-1997, USA.
authors.forename: Sumit
authors.initials: S
authors.lastname: Verma
authors.forename: Rachel
authors.initials: R
authors.lastname: Landisch
authors.forename: Brendan
authors.initials: B
authors.lastname: Quirk
authors.forename: Kathleen
authors.initials: K
authors.lastname: Schmainda
authors.forename: Melissa
authors.initials: M
authors.lastname: Prah
authors.forename: Harry T
authors.initials: HT
authors.lastname: Whelan
authors.forename: Rodney E
authors.initials: RE
authors.lastname: Willoughby
mesh_terms: D001921:Brain / Q000378:metabolism / Q000382:microbiology; D002675:Child, Preschool; D003072:Cognition Disorders / Q000139:chemically induced; D004176:Dipyridamole / Q000627:therapeutic use; D006801:Humans; D006862:Hydrogen Sulfide / Q000378:metabolism*; D006931:Hyperbaric Oxygenation; D008297:Male; D016920:Meningitis, Bacterial / Q000378:metabolism* / Q000382:microbiology*; D009422:Nervous System Diseases / Q000139:chemically induced; D012977:Sodium Nitrite; D013290:Streptococcal Infections / Q000378:metabolism* / Q000382:microbiology*; D034366:Streptococcus anginosus / Q000302:isolation & purification / Q000378:metabolism*
chemical_list: D004176:Dipyridamole; D012977:Sodium Nitrite; D006862:Hydrogen Sulfide