title: A literature review of the numerical analysis of abdominal aortic aneurysms treated with endovascular stent grafts.
abstract: The purpose of this paper is to present the basic principles and relevant advances in the computational modeling of abdominal aortic aneurysms and endovascular aneurysm repair, providing the community with up-to-date state of the art in terms of numerical analysis and biomechanics. Frameworks describing the mechanical behavior of the aortic wall already exist. However, intraluminal thrombus nonhomogeneous structure and porosity still need to be well characterized. Also, although the morphology and mechanical properties of calcifications have been investigated, their effects on wall stresses remain controversial. Computational fluid dynamics usually assumes a rigid artery wall, whereas fluid-structure interaction accounts for artery compliance but is still challenging since arteries and blood have similar densities. We discuss alternatives to fluid-structure interaction based on dynamic medical images that address patient-specific hemodynamics and geometries. We describe initial stresses, elastic boundary conditions, and statistical strength for rupture risk assessment. Special emphasis is accorded to workflow development, from the conversion of medical images into finite element models, to the simulation of catheter-aorta interactions and stent-graft deployment. Our purpose is also to elaborate the key ingredients leading to virtual stenting and endovascular repair planning that could improve the procedure and stent-grafts.
authors.affiliation: Laboratoire Central de Traitement des Images, Research Center, Hôpital Notre-Dame, Centre Hospitalier de l'Université de Montréal-CRCHUM, Montréal, QC H2L 4M1, Canada.
authors.forename: David
authors.initials: D
authors.lastname: Roy
authors.forename: Claude
authors.initials: C
authors.lastname: Kauffmann
authors.forename: Sébastien
authors.initials: S
authors.lastname: Delorme
authors.forename: Sophie
authors.initials: S
authors.lastname: Lerouge
authors.forename: Guy
authors.initials: G
authors.lastname: Cloutier
authors.forename: Gilles
authors.initials: G
authors.lastname: Soulez
mesh_terms: D001011:Aorta / Q000473:pathology; D017544:Aortic Aneurysm, Abdominal / Q000628:therapy*; D001696:Biomechanical Phenomena; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation* / Q000379:methods; D001808:Blood Vessels / Q000473:pathology; D002114:Calcinosis; D057785:Catheters; D003198:Computer Simulation; D020342:Finite Element Analysis; D006439:Hemodynamics; D006801:Humans; D008955:Models, Cardiovascular; D008962:Models, Theoretical; D012212:Rheology; D012306:Risk; D015607:Stents; D013314:Stress, Mechanical