title: Cu(II) Schiff base as catalyst in the synthesis of 1,8-dioxodecahydroacridine.
abstract: The catalytic property of Cu(II) Schiff-base complex in an efficient synthesis of 1,8-dioxodecahydroacridines was investigated. The one-pot three component reaction of dimedone, aromatic aldehydes and aromatic amines or ammonium acetate in water afforded the corresponding 1,8-dioxodecahydroacridines with excellent yields. This reaction was carried out in the presence of 1 mol% of catalysts at room temperature. The reusability of the catalysts was demonstrated by a five-run test without loss of its activity. Also, this catalyst possesses several advantages including mild reaction conditions, lower catalytic loading, shorter reaction times, high yield of the products, inexpensive and cleaner (Green chemistry) reactions.
authors.affiliation: Department of Chemistry, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran. m.vahdat@iauamol.ac.ir
authors.forename: Seyed Mohammad
authors.initials: SM
authors.lastname: Vahdat
authors.forename: Hamid Reza
authors.initials: HR
authors.lastname: Mardani
authors.forename: Hamid
authors.initials: H
authors.lastname: Golchoubian
authors.forename: Maryam
authors.initials: M
authors.lastname: Khavarpour
authors.forename: Saeed
authors.initials: S
authors.lastname: Baghery
authors.forename: Ziba
authors.initials: Z
authors.lastname: Roshankouhi
mesh_terms: D000166:Acridines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D056831:Coordination Complexes / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D055772:Green Chemistry Technology; D012545:Schiff Bases / Q000737:chemistry*
chemical_list: D000166:Acridines; D056831:Coordination Complexes; D012545:Schiff Bases; D003300:Copper