title: An uncommon presentation of ductal carcinoma in situ.
abstract: A 47-year-old woman presented with 6 weeks history of non-blood-stained nipple discharge. Two separate nipple cytology assessments revealed malignant cells despite normal clinical examination and radiological investigation (mammogram, ultrasound and MRI). The patient elected for a central segmentectomy which revealed a 1.8 cm area of high-grade comedo ductal carcinoma in situ in the subareolar region. The patient made a good postoperative recovery. 6 months follow-up revealed a 5 mm area of new calcification, core biopsy revealed atypical cells. After counselling, the patient elected for bilateral mastectomy which revealed fibrocystic tissue only.
authors.affiliation: Antrim Area Hospital, Breast Unit, Antrim, UK.
authors.forename: Rodney
authors.initials: R
authors.lastname: Motindi
authors.forename: Peter
authors.initials: P
authors.lastname: Mallon
authors.forename: Stephen
authors.initials: S
authors.lastname: Dace
mesh_terms: D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D009558:Nipples / Q000378:metabolism / Q000473:pathology