title: Conformational modulation of Ant-Pro oligomers using chirality alteration of proline residues.
abstract: Structural modulation of Ant-Pro (anthranilic acid-proline) oligomers has been carried out by chirality alteration of the proline residues. The results suggest that the chirality altered oligomers show well-defined helical conformation featuring nine-membered hydrogen bonding interactions - without compromising conformational rigidity.
authors.affiliation: Division of Organic Chemistry, National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411 008, India.
authors.forename: Sangram S
authors.initials: SS
authors.lastname: Kale
authors.forename: Amol S
authors.initials: AS
authors.lastname: Kotmale
authors.forename: Achintya Kumar
authors.initials: AK
authors.lastname: Dutta
authors.forename: Sourav
authors.initials: S
authors.lastname: Pal
authors.forename: P R
authors.initials: PR
authors.lastname: Rajamohanan
authors.forename: Gangadhar J
authors.initials: GJ
authors.lastname: Sanjayan
mesh_terms: D002942:Circular Dichroism; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008968:Molecular Conformation; D009842:Oligopeptides / Q000138:chemical synthesis / Q000737:chemistry*; D011392:Proline / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D017510:Protein Folding; D017433:Protein Structure, Secondary; D013237:Stereoisomerism; D062367:ortho-Aminobenzoates / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D009842:Oligopeptides; D062367:ortho-Aminobenzoates; C031385:anthranilic acid; D011392:Proline