title: Tandem age-related lumbar and cervical intervertebral disc changes in asymptomatic subjects.
abstract: OBJECTIVE
  To investigate the frequency of tandem lumbar and cervical intervertebral disc degeneration in asymptomatic subjects.
  
  
  METHODS
  We evaluated magnetic resonance imaging (MRI) results from 94 volunteers (48 men and 46 women; mean age 48 years) for age-related intervertebral disc degeneration in the lumbar and cervical spine.
  
  
  RESULTS
  MRI indicated degenerative changes in the lumbar spine in 79 subjects (84 %), with decreased disc signal intensity in 74.5 %, posterior disc protrusion in 78.7 %, anterior compression of the dura in 81.9 %, disc space narrowing in 21.3 %, and spinal canal stenosis in 12.8 %. These findings were more common in older subjects at caudal levels. MRI showed degenerative changes in both the lumbar and cervical spine in 78.7 % of the volunteers.
  
  
  CONCLUSIONS
  Degenerative findings in both the lumbar and cervical spine, suggesting tandem disc degeneration, was common in asymptomatic subjects. These results provide normative data for evaluating patients with degenerative lumbar and cervical disc diseases.
authors.affiliation: Department of Orthopaedic Surgery, Keio University, Shinanomachi 35, Shinjuku-ku, Tokyo 160-8582, Japan. morio@sc.itc.keio.ac.jp
authors.forename: Morio
authors.initials: M
authors.lastname: Matsumoto
authors.forename: Eijiro
authors.initials: E
authors.lastname: Okada
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Toyama
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Fujiwara
authors.forename: Suketaka
authors.initials: S
authors.lastname: Momoshima
authors.forename: Takeshi
authors.initials: T
authors.lastname: Takahata
mesh_terms: D000328:Adult; D000375:Aging / Q000473:pathology*; D002574:Cervical Vertebrae / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007403:Intervertebral Disc / Q000473:pathology; D055959:Intervertebral Disc Degeneration / Q000453:epidemiology* / Q000473:pathology; D008159:Lumbar Vertebrae / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies