title: [Effect of GABA and glycine neuromediator interaction in the central nervous system].
abstract: Today it is well accepted that GABA can be co-localized and co-released with glycine in the same synapse. This article provides an overview of GABA and glycine co-localization and the effects of simultaneous activation of GABAA and glycine receptors. The review deals with mechanisms of direct and indirect receptor interaction, as well as with the effect of non-selective activation of glycine receptors by GABA.
authors.forename: D V
authors.initials: DV
authors.lastname: Amakhin
authors.forename: N P
authors.initials: NP
authors.lastname: Veselkin
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000187:drug effects / Q000378:metabolism*; D005998:Glycine / Q000378:metabolism* / Q000494:pharmacology; D006801:Humans; D009474:Neurons / Q000187:drug effects / Q000378:metabolism*; D010766:Phosphorylation; D020239:Receptor Cross-Talk / Q000187:drug effects; D018079:Receptors, GABA / Q000378:metabolism*; D018009:Receptors, Glycine / Q000378:metabolism*; D013569:Synapses / Q000187:drug effects / Q000378:metabolism; D055366:Synaptic Potentials / Q000187:drug effects; D005680:gamma-Aminobutyric Acid / Q000378:metabolism* / Q000494:pharmacology
chemical_list: D018079:Receptors, GABA; D018009:Receptors, Glycine; D005680:gamma-Aminobutyric Acid; D005998:Glycine