title: Use of systemic corticosteroids in management of a large congenital haemangioma of the scalp.
abstract: Congenital haemangiomas are rare and are estimated to have a combined incidence of less than 3% of all infantile haemangiomas. They are fully grown at birth, having undergone their proliferative phase in utero. Congenital hemangiomas can present at birth or in some cases can be detected antenatally on imaging. In the majority of patients no therapeutic intervention is required. Congenital hemangiomas also differ from infantile hemangiomas by staining negatively with GLUT1 antibody. They fall into two major subtypes: rapidly involuting congenital hemangiomas (RICHs) and noninvoluting congenital hemangiomas (NICHs). Here we describe a case of RICH detected antenatally on ultrasound imaging. This lesion caused significant complications in the postnatal period due to the bulk of the lesion and the presence of incipient ulceration with the risk of possible catastrophic hemorrhage. A therapeutic trial of oral corticosteroid was commenced in an effort to accelerate involution due to the significant risk associated with other possible treatment modalities such as embolization or surgical intervention.
authors.affiliation: Department of Paediatric Dermatology, Our Lady's Children's Hospital, Dublin, IrelandPaediatric Radiology, Our Lady's Children's Hospital, Dublin, IrelandDepartment of Paediatrics and Child Health, University College Cork, Cork, IrelandDepartment of Obstetrics, University College Cork, Cork, IrelandDepartment of Dermatology, South Infirmary Victoria Hospital, Cork, Ireland.
authors.forename: Bridget Caitriona
authors.initials: BC
authors.lastname: Hackett
authors.forename: Eithne
authors.initials: E
authors.lastname: Phelan
authors.forename: Anthony
authors.initials: A
authors.lastname: Ryan
authors.forename: Louise
authors.initials: L
authors.lastname: Kenny
authors.forename: Michelle
authors.initials: M
authors.lastname: Murphy
authors.forename: Alan D
authors.initials: AD
authors.lastname: Irvine
authors.forename: Rosemarie M
authors.initials: RM
authors.lastname: Watson
mesh_terms: D000284:Administration, Oral; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D005260:Female; D006391:Hemangioma / Q000151:congenital / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D012074:Remission Induction; D012535:Scalp / Q000473:pathology*; D012878:Skin Neoplasms / Q000151:congenital / Q000188:drug therapy / Q000473:pathology
chemical_list: D000305:Adrenal Cortex Hormones