title: Diabetic cardiomyopathy: bench to bedside.
abstract: The study of diabetic cardiomyopathy is an area of significant interest given the strong association between diabetes and the risk of heart failure. Many unanswered questions remain regarding the clinical definition and pathogenesis of this metabolic cardiomyopathy. This article reviews the current understanding of diabetic cardiomyopathy with a particular emphasis on the unresolved issues that have limited translation of scientific discovery to patient bedside.
authors.affiliation: Diabetic Cardiovascular Disease Center, Division of Cardiology, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA. jschilli@dom.wustl.edu
authors.forename: Joel D
authors.initials: JD
authors.lastname: Schilling
authors.forename: Douglas L
authors.initials: DL
authors.lastname: Mann
mesh_terms: D003920:Diabetes Mellitus / Q000188:drug therapy / Q000473:pathology*; D058065:Diabetic Cardiomyopathies / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism; D018450:Disease Progression; D005230:Fatty Acids, Nonesterified / Q000378:metabolism; D006801:Humans; D007249:Inflammation; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D008928:Mitochondria / Q000378:metabolism / Q000473:pathology; D009203:Myocardial Infarction / Q000209:etiology; D009206:Myocardium / Q000378:metabolism / Q000473:pathology*; D018384:Oxidative Stress; D011379:Prognosis; D012307:Risk Factors
chemical_list: D005230:Fatty Acids, Nonesterified