title: SIOP PODC: clinical guidelines for the management of children with Wilms tumour in a low income setting.
abstract: Wilms tumour is a relatively common and curable paediatric tumour. Known challenges to cure in low income countries are late presentation with advanced disease, malnutrition, failure to complete treatment and limited facilities. In this article, management recommendations are given for a low income setting where only the minimal requirements for treatment with curative intent are available (setting 1). These include general management, supportive care, social support and registration of patients. Recommendations specific for Wilms tumour care include diagnostic procedures with emphasis on the role of ultrasonography, preoperative chemotherapy with a reduced dosage for malnourished children and postoperative chemotherapy based on surgical staging.
authors.affiliation: Department of Paediatric Oncology, VU University Medical Center, Amsterdam, The Netherlands. t.israels@vumc.nl
authors.forename: Trijn
authors.initials: T
authors.lastname: Israels
authors.forename: Claude
authors.initials: C
authors.lastname: Moreira
authors.forename: Trish
authors.initials: T
authors.lastname: Scanlan
authors.forename: Liz
authors.initials: L
authors.lastname: Molyneux
authors.forename: Sam
authors.initials: S
authors.lastname: Kampondeni
authors.forename: Peter
authors.initials: P
authors.lastname: Hesseling
authors.forename: Hugo
authors.initials: H
authors.lastname: Heij
authors.forename: Eric
authors.initials: E
authors.lastname: Borgstein
authors.forename: Gordan
authors.initials: G
authors.lastname: Vujanic
authors.forename: Kathy
authors.initials: K
authors.lastname: Pritchard-Jones
authors.forename: Larry
authors.initials: L
authors.lastname: Hadley
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D009367:Neoplasm Staging; D011203:Poverty; D012944:Social Support; D009396:Wilms Tumor / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*