title: Cerebral hemorrhage due to posterior reversible encephalopathy syndrome associated with autonomic dysreflexia in a spinal cord injury patient.
abstract: A 37-year-old man with C4-5 spinal cord injury (SCI) presented with abnormally high blood pressure after vesicocutaneous catheter exchange and was treated with antihypertensive agents. Two weeks later, he developed headache and visual disturbance, and presented with fluctuating blood pressure. Multiple subcortical hemorrhages in the left occipital and right frontal lobes occurred on the next day, and he died of increased intracranial pressure 3 weeks later. Based on the symptoms and computed tomography findings, the retrospective diagnosis was posterior reversible encephalopathy syndrome (PRES) due to autonomic dysreflexia (AD). AD occurs frequently in patients with quadriplegia and high paraplegia by distention of the bladder and bowel. PRES secondary to AD is very rare, but we must always be aware of this life-threatening complication in SCI patients.
authors.affiliation: Department of Neurosurgery, Hamamatsu University School of Medicine, Shizuoka, Japan.
authors.forename: Tae
authors.initials: T
authors.lastname: Yamashita
authors.forename: Hisaya
authors.initials: H
authors.lastname: Hiramatsu
authors.forename: Naoto
authors.initials: N
authors.lastname: Sakai
authors.forename: Hiroki
authors.initials: H
authors.lastname: Namba
mesh_terms: D000063:Accidents, Traffic; D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D020211:Autonomic Dysreflexia / Q000209:etiology*; D002543:Cerebral Hemorrhage / Q000209:etiology*; D002574:Cervical Vertebrae / Q000293:injuries*; D003248:Constipation / Q000209:etiology / Q000503:physiopathology; D017809:Fatal Outcome; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology; D019586:Intracranial Hypertension / Q000209:etiology; D008297:Male; D054038:Posterior Leukoencephalopathy Syndrome / Q000209:etiology*; D011311:Pressoreceptors / Q000502:physiology; D011312:Pressure; D011782:Quadriplegia / Q000209:etiology; D012007:Rectum / Q000503:physiopathology; D013119:Spinal Cord Injuries / Q000150:complications*; D001743:Urinary Bladder / Q000503:physiopathology; D014546:Urinary Catheterization; D016055:Urinary Retention / Q000209:etiology / Q000503:physiopathology / Q000628:therapy
chemical_list: D000959:Antihypertensive Agents