title: Angiotensin-converting enzyme inhibitor-induced unilateral tongue angioedema.
abstract: Angioedema is a frequently reported side effect of angiotensin-converting enzyme inhibitors. The literature suggests that immunosuppressed transplant patients are at an increased risk for this adverse condition. A 62-year-old African American man presented with acute unilateral angioedema attributed to angiotensin-converting enzyme inhibitor initiation. A PubMed literature search regarding unilateral angioedema produced only 3 reported cases confirming an uncommon presentation of an otherwise common adverse drug event. The cases raised questions regarding evidence-based management of drug-induced angioedema, effectiveness of current medical management regimens and the potential of other treatment options. Our objective was to review the presentation, diagnosis and acute management of a common adverse drug effect based on an uncommon patient presentation.
authors.affiliation: Department of Internal Medicine, Medical University of South Carolina, Charleston, SC 29425, USA. kuhlen@musc.edu
authors.forename: James Lee
authors.initials: JL
authors.lastname: Kuhlen
authors.forename: Jessica
authors.initials: J
authors.lastname: Forcucci
mesh_terms: D000799:Angioedema / Q000139:chemically induced*; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014060:Tongue Diseases / Q000139:chemically induced*
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors