title: Molecular catch and release: controlled delivery using optical trapping with light-responsive liposomes.
abstract: Gold-coated liposomes are maneuvered using an optical trap to achieve precise delivery of encapsulated molecular cargo. Movement and payload release from these plasmon resonant nanocapsules are independently controlled using a pulsed trapping beam. This technology enables in vitro delivery of a payload to a selected cell and may be applied to the interrogation of individual cells within their biological microenvironment.
authors.affiliation: Department of Biomedical Engineering, University of Arizona, Tucson, 85721, USA.
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: Leung
authors.forename: Marek
authors.initials: M
authors.lastname: Romanowski
mesh_terms: D016503:Drug Delivery Systems / Q000295:instrumentation / Q000379:methods*; D006046:Gold / Q000737:chemistry; D057809:HEK293 Cells; D006801:Humans; D008027:Light; D008081:Liposomes / Q000737:chemistry*; D052898:Optical Tweezers
chemical_list: D008081:Liposomes; D006046:Gold