title: Two-step one-pot synthesis of benzoannulated spiroacetals by Suzuki-Miyaura coupling/acid-catalyzed spiroacetalization.
abstract: Substituted benzoannulated spiroacetals were prepared from (2-haloaryl)alkyl alcohols and dihydropyranyl or dihydrofuranyl pinacol boronates using a Suzuki-Miyaura coupling followed by an acid-catalyzed spirocyclization. Application of the reaction to a glycal boronate provides an approach to annulated spiroacetals in enantiopure form.
authors.affiliation: Laboratoire de Chimie Organique, ESPCI ParisTech, CNRS, 10 rue Vauquelin, 75231 Paris Cedex 05, France.
authors.forename: Alexey N
authors.initials: AN
authors.lastname: Butkevich
authors.forename: Andrei
authors.initials: A
authors.lastname: Corbu
authors.forename: Lieven
authors.initials: L
authors.lastname: Meerpoel
authors.forename: Ian
authors.initials: I
authors.lastname: Stansfield
authors.forename: Patrick
authors.initials: P
authors.lastname: Angibaud
authors.forename: Pascal
authors.initials: P
authors.lastname: Bonnet
authors.forename: Janine
authors.initials: J
authors.lastname: Cossy
mesh_terms: D000080:Acetals / Q000138:chemical synthesis*; D000143:Acids / Q000737:chemistry; D001554:Benzene / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D003847:Deoxyglucose / Q000737:chemistry; D015394:Molecular Structure; D013141:Spiro Compounds / Q000138:chemical synthesis*
chemical_list: D000080:Acetals; D000143:Acids; D013141:Spiro Compounds; D003847:Deoxyglucose; D001554:Benzene