title: An efficient approach for the construction of benzazepine and benzoxepine derivatives.
abstract: A novel and facile synthetic protocol for the construction of benzazepine and benzoxepine derivatives through a copper(I)-catalyzed reaction of 2-(2-ethynylphenyl)-1-tosylaziridine or 2-(2-ethynylphenyl)oxirane with sulfonyl azides is disclosed. A ketenimine is the key intermediate during the reaction process.
authors.affiliation: Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.
authors.forename: Shaoyu
authors.initials: S
authors.lastname: Li
authors.forename: Shaowu
authors.initials: S
authors.lastname: Zou
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
mesh_terms: D001552:Benzazepines / Q000138:chemical synthesis* / Q000737:chemistry; D001584:Benzoxepins / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D003500:Cyclization
chemical_list: D001552:Benzazepines; D001584:Benzoxepins; D003300:Copper