title: Residue-residue contacts: application to analysis of secondary structure interactions.
abstract: Protein structures and their complexes are formed and stabilized by interactions, both inside and outside of the protein. Analysis of such interactions helps in understanding different levels of structures (secondary, super-secondary, and oligomeric states). It can also assist molecular biologists in understanding structural consequences of modifying proteins and/or ligands. In this chapter, our definition of atom-atom and residue-residue contacts is described and applied to analysis of protein-protein interactions in dimeric β-sandwich proteins.
authors.affiliation: Department of Biology, MIT, Cambridge, MA, USA.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Potapov
authors.forename: Marvin
authors.initials: M
authors.lastname: Edelman
authors.forename: Vladimir
authors.initials: V
authors.lastname: Sobolev
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D006860:Hydrogen Bonding; D057927:Hydrophobic and Hydrophilic Interactions; D008958:Models, Molecular; D011485:Protein Binding; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism
chemical_list: D000596:Amino Acids; D011506:Proteins