title: Child maltreatment, dating perpetration of physical assault, and cortisol reactivity among disadvantaged female adolescents.
abstract: OBJECTIVE
  Few studies have examined hypothalamic-pituitary-adrenal axis stress reactivity and its relationship to histories of child maltreatment and physical aggression. We examined the relation of a history of childhood sexual abuse (CSA) and perpetration of dating violence to patterns of cortisol change before (resting) and after (reactivity) exposure to a laboratory stressor.
  
  
  METHODS
  In a sample of 40 disadvantaged sexually active female adolescent patients (ages 14-17 years), we collected self-reports of lifetime child maltreatment (5 types) and past-year female perpetration of physical assault (PA) acts toward a romantic partner. We assessed changes in salivary cortisol trajectories during resting and reactivity phases following the viewing of a teen dating violence vignette.
  
  
  RESULTS
  Reports of CSA (CSA+ group) were associated with reports of perpetration of severe dating PA (PA+ group), but the relation of these reports to laboratory-assessed patterns of cortisol changes following the stressor was opposite. As compared with subjects without victimization or perpetration histories (referent group), the CSA+ group showed the most pronounced positive slope (reactivity), whereas the PA+ group showed the least positive slope following the laboratory stressor after the overlap between these groups was statistically adjusted. While showing less reactivity to the laboratory stressor, the PA+ group had higher levels of resting cortisol, which stayed high during reactivity as compared to the referent group.
  
  
  CONCLUSIONS
  The laboratory paradigm to elicit neuroendocrine stress-related cortisol reactivity appears to be a promising tool for identifying altered cortisol physiology among female adolescents with mixed histories of CSA and perpetration of dating PA.
authors.affiliation: Mount Sinai Adolescent Health Center, New York, NY 10128, USA. oriana.linares@mountsinai.org
authors.forename: L Oriana
authors.initials: LO
authors.lastname: Linares
authors.forename: Patrick E
authors.initials: PE
authors.lastname: Shrout
authors.forename: Anne
authors.initials: A
authors.lastname: Nucci-Sack
authors.forename: Angela
authors.initials: A
authors.lastname: Diaz
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior / Q000502:physiology* / Q000523:psychology*; D000374:Aggression / Q000502:physiology* / Q000523:psychology*; D002650:Child Abuse, Sexual / Q000523:psychology*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism*; D010775:Photic Stimulation; D012463:Saliva / Q000378:metabolism; D014754:Violence / Q000523:psychology; D035862:Vulnerable Populations / Q000523:psychology*
chemical_list: D006854:Hydrocortisone