title: Depth of suppression in anisometropic amblyopia (with or without microtropia).
abstract: OBJECTIVE
  There are conflicting reports concerning the relationship between depth of suppression and  level of amblyopia in strabismics. Little attention has been given to anisometropes. This study examines the density of suppression in anisometropic amblyopes, with or without microtropia, and investigates whether there is a relationship with level of amblyopia.
  
  
  METHODS
  Patients with anisometropia (defined as a difference of 1D or 0.5 D cyl), binocular single vision and a difference in corrected visual acuity of at least 0.1 logMAR between eyes were recalled. The degree of amblyopia was expressed as the interocular difference using the Bailey-Lovie logMAR chart. Stereoacuity (Titmus test), binocular alignment and fixation were recorded. The depth of suppression was measured using the neutral density filter bar together with the Worth four dot test at 4.5m (subtending an angle of 0.5 degrees). Best spherical equivalent (BSE) was calculated to represent anisometropia.
  
  
  RESULTS
  Thirteen participants aged 8.3 years to 12.1 years (mean 9.7 years) completed the study.  No significant correlation was present (r=0.10, p=0.74) between the depth of suppression and degree of amblyopia.  However, there was a correlation between depth of suppression and level of stereoacuity (r=0.59, p=0.03). Six participants had microtropia and showed stronger suppression (p=0.03) and worse stereoacuity (p=0.001) than the pure anisometropes.
  
  
  CONCLUSIONS
  No evidence was found of a relationship between density of suppression and amblyopia in this cohort of anisometropic amblyopes.
authors.forename: Alison Y
authors.initials: AY
authors.lastname: Firth
authors.forename: Clare
authors.initials: C
authors.lastname: Stevenson
mesh_terms: D000550:Amblyopia; D015858:Anisometropia; D005123:Eye; D006801:Humans; D013285:Strabismus; D014792:Visual Acuity