title: [Comparative study on effects between electroacupuncture and acupuncture for spastic paralysis after stroke].
abstract: OBJECTIVE
  To observe the differences of therapeutic effect of spastic paralysis after stroke between electroacupuncture and acupuncture and explore the mechanism.
  
  
  METHODS
  Sixty-four cases were randomly divided into an electroacupuncture group (n = 33) and an acupuncture group (n = 31). Both groups were treated with Bobath facilitation techniques and medicine treatments. Quchi (LI 11), Hegu (LI 4), Yanglingquan (GB 34), Sanyinjiao (SP 6), et al. on the affected side were selected in each group. The needle was retained for 30 min, and the manipulation was applied for 1 min in the acupuncture group, and electroacupuncture was added in the electroacupuncture group. Stroke Impairment Assessment Set (SIAS) was adopted to assess the whole function status after sroke, and the contents of glutamate (Glu) and gamma-aminobutyric acid (GABA) in serum and clinical efficacy were observed in the two groups.
  
  
  RESULTS
  The SIAS score increased after treatment as compared with that before treatment in either group (both P < 0.01), and the electroacupuncture group was superior to the acupuncture group (P < 0.01); the content of Glu in blood serum and ratio of Glu/GABA reduced, while the content of GABA in serum increased after treatment as compared with those before treatment in either group (all P < 0.01), but the improvement of above indices were much more apparently in the electroacupuncture group as compared with those in the acupuncture group (P < 0.01, P < 0.05); the total effective rate of 90.9% (30/33) in the electroacupuncture group was superior to that of 83.9% (26/31) in the acupuncture group (P < 0.05).
  
  
  CONCLUSIONS
  Electroacupuncture can improve therapeutic effect of spastic paralysis after stroke, it's mechanism may be ralated to ajusting the contents of Glu and GABA in serum.
authors.affiliation: College of Acupuncture-Moxibustion and Massage, Hunan University of TCM, Changsha 410208, China.
authors.forename: Zeng-Hui
authors.initials: ZH
authors.lastname: Yue
authors.forename: Liang
authors.initials: L
authors.lastname: Li
authors.forename: Xiao-Rong
authors.initials: XR
authors.lastname: Chang
authors.forename: Jing-Ming
authors.initials: JM
authors.lastname: Jiang
authors.forename: Le-Le
authors.initials: LL
authors.lastname: Chen
authors.forename: Xiao-Shan
authors.initials: XS
authors.lastname: Zhu
mesh_terms: D015670:Acupuncture Therapy; D015671:Electroacupuncture; D018698:Glutamic Acid / Q000097:blood; D009128:Muscle Spasticity; D010243:Paralysis / Q000097:blood / Q000628:therapy*; D020521:Stroke / Q000097:blood / Q000628:therapy*; D005680:gamma-Aminobutyric Acid / Q000097:blood
chemical_list: D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid