title: [The application of stereology in radiology imaging and cell biology fields].
abstract: Stereology is an interdisciplinary method for 3D morphological study developed from mathematics and morphology. It is widely used in medical image analysis and cell biology studies. Because of its unbiased, simple, fast, reliable and non-invasive characteristics, stereology has been widely used in biomedical areas for quantitative analysis and statistics, such as histology, pathology and medical imaging. Because the stereological parameters show distinct differences in different pathology, many scholars use stereological methods to do quantitative analysis in their studies in recent years, for example, in the areas of the condition of cancer cells, tumor grade, disease development and the patient's prognosis, etc. This paper describes the stereological concept and estimation methods, also illustrates the applications of stereology in the fields of CT images, MRI images and cell biology, and finally reflects the universality, the superiority and reliability of stereology.
authors.affiliation: Biomedical Engineering Major, Precision Instrument & Opto-Electronics Engineering College, Tianjin University, Tianjin 30072, China.
authors.forename: Na
authors.initials: N
authors.lastname: Hu
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.forename: Yuanming
authors.initials: Y
authors.lastname: Feng
authors.forename: Wang
authors.initials: W
authors.lastname: Lin
mesh_terms: D000715:Anatomy / Q000379:methods*; D000818:Animals; D001699:Biometry / Q000379:methods*; D003585:Cell Biology; D003584:Cytological Techniques / Q000379:methods*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging; D014057:Tomography, X-Ray Computed