title: Soft J-tipped guide wire-induced cardiac perforation in a patient with right ventricular lipomatosis and wall thinning.
abstract: Cardiac tamponade caused by perforation is a rare but potentially lethal complication of central venous catheter (CVC) insertion. We herein report a case of cardiac perforation associated with the use of a soft J-tipped guide wire. Twenty minutes after the insertion of a CVC, the patient developed unexpected cardiac arrest. An autopsy revealed 400 mL of pericardial blood. The right ventricular wall was 1 mm thick with about 10 myocyte layers, which is one-third that of the normal heart. A histological analysis revealed widespread fatty infiltration of the right ventricular wall (right ventricular lipomatosis).
authors.affiliation: Departments of Neurology, Hematology, Metabolism, Endocrinology, and Diabetology, Yamagata University School of Medicine, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Hiroshima
authors.forename: Katsushi
authors.initials: K
authors.lastname: Tajima
authors.forename: Yousuke
authors.initials: Y
authors.lastname: Shiono
authors.forename: Ikuko
authors.initials: I
authors.lastname: Suzuki
authors.forename: Kei
authors.initials: K
authors.lastname: Kohno
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Kato
authors.forename: Kawamura
authors.initials: K
authors.lastname: Shunji
authors.forename: Takeo
authors.initials: T
authors.lastname: Kato
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage; D062905:Central Venous Catheters / Q000009:adverse effects*; D017809:Fatal Outcome; D006323:Heart Arrest / Q000209:etiology / Q000401:mortality; D006335:Heart Injuries / Q000150:complications / Q000209:etiology*; D006352:Heart Ventricles / Q000473:pathology*; D006801:Humans; D008068:Lipomatosis; D008223:Lymphoma / Q000188:drug therapy; D008297:Male
chemical_list: D000970:Antineoplastic Agents