title: The role of mass spectrometry in the analysis of vitamin D compounds.
abstract: This review highlights the superseding role of mass spectrometry in the structural characterization and quantitation of vitamin D compounds in comparison to other analytical methods (e.g., UV, bioassays) that lack the sensitivity and specificity of mass spectrometry. After a short introduction to the biochemistry of vitamin D compounds, an overview of the current techniques to characterize and quantitate vitamin D compounds is given with emphasis on the contribution of mass spectrometry.
authors.affiliation: Barnett Institute of Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, USA.
authors.forename: Rose M
authors.initials: RM
authors.lastname: Gathungu
authors.forename: Caroline C
authors.initials: CC
authors.lastname: Flarakos
authors.forename: G Satyanarayana
authors.initials: GS
authors.lastname: Reddy
authors.forename: Paul
authors.initials: P
authors.lastname: Vouros
mesh_terms: D000818:Animals; D002853:Chromatography, Liquid / Q000379:methods / Q000706:statistics & numerical data; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods*; D014807:Vitamin D / Q000031:analogs & derivatives / Q000737:chemistry* / Q000378:metabolism
chemical_list: D014807:Vitamin D