title: Myoepithelial carcinoma of the retromolar area with extensive mandibular involvement.
abstract: Myoepithelial tumors were first described in 1943, and account for less than 1% of all salivary gland neoplasms. Their malignant variant, myoepithelial carcinoma, was first reported by Stromeyer et al. in 1975 and represents a very rare entity, characterized by distinct morphologic heterogeneity and an infiltrative growth pattern into adjacent tissues. However, there have been few reports on myoepithelial carcinoma affecting intra-oral minor salivary glands, and its immunohistochemical features have been poorly illustrated. We herein describe a rare case of myoepithelial carcinoma affecting the retromolar region of a 52-year-old woman that caused extensive mandibular bone destruction. We also reviewed the English literature concerning the involvement of intra-oral minor salivary glands by myoepithelial carcinoma.
authors.affiliation: Service of Oral Pathology, João de Barros Barreto University Hospital, Federal University of Pará, Pará, Brazil.
authors.forename: Hélder Antônio Rebelo
authors.initials: HA
authors.lastname: Pontes
authors.forename: Flávia Sirotheau Corrêa
authors.initials: FS
authors.lastname: Pontes
authors.forename: Victor
authors.initials: V
authors.lastname: Toral-Rizo
authors.forename: Bruno Augusto Benevenuto
authors.initials: BA
authors.lastname: de Andrade
authors.forename: Felipe Paiva
authors.initials: FP
authors.lastname: Fonseca
authors.forename: Oslei Paes
authors.initials: OP
authors.lastname: de Almeida
mesh_terms: D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D008963:Molar; D009208:Myoepithelioma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D010014:Osteolysis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D012468:Salivary Gland Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D012470:Salivary Glands, Minor / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome