title: Eosinophilic ulcer of the oral mucosa.
abstract: A 56-year-old woman presented with a painless lesion on the inner aspect of her upper lip. The clinical differential diagnoses were oral syphilitic chancre, tuberculosis, histoplamosis, and neoplasia. A biopsy was performed, and the histopathologic diagnosis revealed an eosinophilic ulcer of the oral mucosa. Based on this case, we discuss the history, mechanisms of pathogenesis, clinical manifestations, histopathology, differential diagnosis, and therapy of eosinophilic ulcer of the oral mucosa.
authors.affiliation: Sector of Dermatology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Paula Cabral de Menezes
authors.initials: PC
authors.lastname: Gurfinkel
authors.forename: Andrea Cabral de Menezes
authors.initials: AC
authors.lastname: Gurfinkel
authors.forename: Tullia
authors.initials: T
authors.lastname: Cuzzi
authors.forename: Marcia
authors.initials: M
authors.lastname: Ramos-e-Silva
mesh_terms: D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000378:metabolism / Q000473:pathology; D004804:Eosinophils / Q000378:metabolism; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009061:Mouth Mucosa / Q000378:metabolism / Q000473:pathology; D019226:Oral Ulcer / Q000378:metabolism / Q000473:pathology