title: The influence of selected demographic factors and wound location on the concentration of vascular endothelial growth factor (VEGF-A) in the wound healing process after neurosurgery: brief report.
abstract: The main aim of the work was to estimate the influence of selected demographic factors and wound location on the concentration of the vascular endothelial growth factor (VEGF-A) in patients after neurosurgical operations. The study included 20 adult patients who received a surgical treatment because of degenerative spine changes. Measurements of the concentration of the VEGF-A in the patients' blood serum were taken three times (the first time--before the operation; the second time--during the first 24 hours after surgery; and the third time--between the fifth and the seventh day after the operation). No statistically significant correlation between the concentration of VEGF-A in the patients' blood serum before and after the operation was noted. A statistically significant correlation between the concentration of VEGF-A in the individual measurements was found. It can be concluded that people with a higher concentration of VEGF-A before surgery obtained a higher concentration of VEGF-A in the measurements taken after the operation. There is a statistically significant link between the patient's age and the concentration of VEGF-A during the immediate postoperative period (the older the patient, the higher the level of VEGF-A is observed).
authors.affiliation: Neurological and Neurosurgical Nursing Department, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Torun, Poland. zpielnin@cm.umk.pl
authors.forename: Robert
authors.initials: R
authors.lastname: Slusarz
authors.forename: Grażyna
authors.initials: G
authors.lastname: Gadomska
authors.forename: Monika
authors.initials: M
authors.lastname: Biercewicz
authors.forename: Lech
authors.initials: L
authors.lastname: Grzelak
authors.forename: Maria T
authors.initials: MT
authors.lastname: Szewczyk
authors.forename: Danuta
authors.initials: D
authors.lastname: Rość
authors.forename: Wojciech
authors.initials: W
authors.lastname: Beuth
mesh_terms: D000328:Adult; D000367:Age Factors; D002574:Cervical Vertebrae / Q000293:injuries / Q000378:metabolism*; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000293:injuries / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures; D011184:Postoperative Period; D013997:Time Factors; D042461:Vascular Endothelial Growth Factor A / Q000378:metabolism*; D014945:Wound Healing
chemical_list: D042461:Vascular Endothelial Growth Factor A