title: Synthetic biomimetic membranes and their sensor applications.
abstract: Synthetic biomimetic membranes provide biological environments to membrane proteins. By exploiting the central roles of biological membranes, it is possible to devise biosensors, drug delivery systems, and nanocontainers using a biomimetic membrane system integrated with functional proteins. Biomimetic membranes can be created with synthetic lipids or block copolymers. These amphiphilic lipids and polymers self-assemble in an aqueous solution either into planar membranes or into vesicles. Using various techniques developed to date, both planar membranes and vesicles can provide versatile and robust platforms for a number of applications. In particular, biomimetic membranes with modified lipids or functional proteins are promising platforms for biosensors. We review recent technologies used to create synthetic biomimetic membranes and their engineered sensors applications.
authors.affiliation: Institute of Life Sciences and Resources & Department of Food Science and Biotechnology, Kyung Hee University, Yongin 446-701, Korea. youngkim@khu.ac.kr
authors.forename: Young-Rok
authors.initials: YR
authors.lastname: Kim
authors.forename: Sungho
authors.initials: S
authors.lastname: Jung
authors.forename: Hyunil
authors.initials: H
authors.lastname: Ryu
authors.forename: Yeong-Eun
authors.initials: YE
authors.lastname: Yoo
authors.forename: Sun Min
authors.initials: SM
authors.lastname: Kim
authors.forename: Tae-Joon
authors.initials: TJ
authors.lastname: Jeon