title: Dental implant stability is influenced by implant diameter and localization and by the use of plasma rich in growth factors.
abstract: OBJECTIVE
  The objective was to analyze the factors that influence the stability of dental implants at 12 weeks after implant placement as measured by resonance frequency analysis using the Osstell system.
  
  
  METHODS
  This prospective clinical study was performed in 235 implants placed in 93 patients at the Oral Surgery and Implantology Clinic of the University of Granada. The gathered predictor variables were grouped into patient variables, implant variables, operative variables, and baseline implant stability quotient (ISQ). All variables were analyzed in a multivariate model to determine their influence on the ISQ score at 12 weeks after implant insertion (outcome variable). SUDAAN software was used for clustered sampling (multiple implants in patients).
  
  
  RESULTS
  Two hundred thirty-five dental implants were placed in 47 men (50.5%) and 46 women (49.5%; total, 93 patients; mean age, 52.13 ± 11.23 years; range, 27 to 76 years). No association was found between the patient variables and the ISQ values at 12 weeks. Among implant variables, worse ISQ values at 12 weeks were observed for a narrow diameter (P < .001) and maxillary implants (P = .006). Among surgical technique variables, the use of plasma rich in growth factors (P = .011) showed the best ISQ values at 12 weeks.
  
  
  CONCLUSIONS
  The diameter and localization of implants and the application of plasma rich in growth factors influenced the stability of implants measured at 12 weeks of wound healing. Accordingly, stability was less with a narrower implant diameter and maxillary localization and greater with implants humidified with plasma rich in growth factors.
authors.affiliation: Department of Oral Surgery and Maxillofacial Surgery, School of Dentistry, University of Granada, Granada, Spain. mpilquesada@hotmail.com
authors.forename: Ma Pilar
authors.initials: MP
authors.lastname: Quesada-García
authors.forename: Estrella
authors.initials: E
authors.lastname: Prados-Sánchez
authors.forename: Ma Victoria
authors.initials: MV
authors.lastname: Olmedo-Gaya
authors.forename: Esther
authors.initials: E
authors.lastname: Muñoz-Soto
authors.forename: Manuel
authors.initials: M
authors.lastname: Vallecillo-Capilla
authors.forename: Manuel
authors.initials: M
authors.lastname: Bravo
mesh_terms: D000328:Adult; D000368:Aged; D015519:Bone Density / Q000502:physiology; D003758:Dental Implantation, Endosseous / Q000295:instrumentation / Q000379:methods; D015921:Dental Implants; D017267:Dental Prosthesis Design; D017268:Dental Prosthesis Retention; D019232:Dental Restoration Failure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology; D053657:Platelet-Rich Plasma / Q000502:physiology*; D011446:Prospective Studies; D007507:Therapeutic Irrigation / Q000379:methods; D016896:Treatment Outcome; D014732:Vibration
chemical_list: D015921:Dental Implants