title: Phase response theory extended to nonoscillatory network components.
abstract: New tools for analysis of oscillatory networks using phase response theory (PRT) under the assumption of pulsatile coupling have been developed steadily since the 1980s, but none have yet allowed for analysis of mixed systems containing nonoscillatory elements. This caveat has excluded the application of PRT to most real systems, which are often mixed. We show that a recently developed tool, the functional phase resetting curve (fPRC), provides a serendipitous benefit: it allows incorporation of nonoscillatory elements into systems of oscillators where PRT can be applied. We validate this method in a model system of neural oscillators and a biological system, the pyloric network of crustacean decapods.
authors.affiliation: Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, 30332, USA. fred.sieling@emory.edu
authors.forename: Fred H
authors.initials: FH
authors.lastname: Sieling
authors.forename: Santiago
authors.initials: S
authors.lastname: Archila
authors.forename: Ryan
authors.initials: R
authors.lastname: Hooper
authors.forename: Carmen C
authors.initials: CC
authors.lastname: Canavier
authors.forename: Astrid A
authors.initials: AA
authors.lastname: Prinz
mesh_terms: D000818:Animals; D033364:Decapoda / Q000166:cytology; D008959:Models, Neurological; D008962:Models, Theoretical; D009415:Nerve Net / Q000166:cytology; D055585:Physical Phenomena; D013569:Synapses / Q000378:metabolism