title: [Role of in vivo confocal microscopy in irido-corneo-endothelial syndromes].
abstract: BACKGROUND
  In vivo confocal microscopy (IVCM) is an increasingly utilized tool in studying complex corneal and anterior segment pathologies. We illustrate the role of this imaging technique in the irido-corneo-endothelial (ICE) syndromes through a case report.
  
  
  METHODS
  A 47-year-old woman presented unilateral decreased vision associated with ocular hypertension and peripheral anterior synechiae. Slit lamp examination of the cornea was unremarkable but IVCM showed pleomorphism and polymegathism of the corneal endothelium and highly reflective nuclei resulting in an epithelial-like cell morphology. This appearance led to the diagnosis of ICE syndrome.
  
  
  CONCLUSIONS
  Confocal microscopic findings in ICE syndromes are similar to histopathologic findings. This technique may be for a useful diagnostic adjunct in ICE syndromes by revealing specific characteristics, particularly in difficult diagnostic situations, such as when corneal edema impedes specular microscopy or when the iris fails to demonstrate pathognomonic anomalies.
authors.affiliation: Centre hospitalier national d'ophtalmologie des Quinze-Vingts, 28, rue de Charenton, 75012 Paris, France. violainecaillaux@gmail.com
authors.forename: V
authors.initials: V
authors.lastname: Caillaux
authors.forename: A
authors.initials: A
authors.lastname: Labbé
authors.forename: I
authors.initials: I
authors.lastname: Goemaere
authors.forename: N
authors.initials: N
authors.lastname: Lecuen
authors.forename: L
authors.initials: L
authors.lastname: Laroche
authors.forename: V
authors.initials: V
authors.lastname: Borderie
mesh_terms: D003316:Corneal Diseases / Q000473:pathology*; D004728:Endothelium, Corneal / Q000473:pathology*; D005260:Female; D006801:Humans; D007499:Iris Diseases / Q000473:pathology*; D018613:Microscopy, Confocal / Q000379:methods; D008875:Middle Aged; D013577:Syndrome