title: Co-infection with group A Streptococci and Epstein-Barr virus presenting with acute glomerulonephritis and acute left ventricular dysfunction.
abstract: Acute pharyngitis is commonly encountered, but a definite etiological diagnosis is difficult. Although co-infection with Group A Streptococci (GAS) and Epstein-Barr virus (EBV) is uncommon, general physicians should consider the possibility of EBV co-infection in patients with GAS pharyngitis who fail to show prompt remission of symptoms following appropriate antibiotic treatment. In this article, we present a rare case of a 16-year-old girl who had co-infection with GAS and EBV. She developed acute glomerulonephritis and left ventricular dysfunction in an overlapping manner. We were able to follow her until she healed, and herein describe the pathogenesis of her systemic and pulmonary edema.
authors.affiliation: The First Department of Comprehensive Medicine, Jichi Medical University Saitama Medical Center, Japan.
authors.forename: Tamami
authors.initials: T
authors.lastname: Watanabe
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Sugawara
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tamura
authors.forename: Akira
authors.initials: A
authors.lastname: Ishii
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsubayashi
authors.forename: Masafumi
authors.initials: M
authors.lastname: Kakei
authors.forename: Shin-ichi
authors.initials: S
authors.lastname: Momomura
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D060085:Coinfection / Q000150:complications*; D020031:Epstein-Barr Virus Infections / Q000150:complications* / Q000821:virology; D005260:Female; D005921:Glomerulonephritis / Q000175:diagnosis / Q000209:etiology*; D004854:Herpesvirus 4, Human; D006801:Humans; D011654:Pulmonary Edema / Q000175:diagnosis / Q000209:etiology; D013902:Radiography, Thoracic; D013290:Streptococcal Infections / Q000150:complications* / Q000382:microbiology; D013297:Streptococcus pyogenes; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis / Q000209:etiology*