title: Failed weaning from mechanical ventilation and cardiac dysfunction.
abstract: Failure to transition patient from controlled mechanical ventilation to spontaneous breathing trials (SBTs) in a timely fashion is associated with significant morbidity and mortality in the intensive care unit. In addition, weaning failures are common in patients with limited cardiac reserves. Recent advances in cardiac echocardiography and laboratory measurement of serum biomarkers to assess hemodynamic response to SBT may provide additional information to guide clinicians to predict weaning outcome.
authors.affiliation: VA Western New York Healthcare System, Division of Critical Care Medicine, Department of Anesthesiology and Medicine, Buffalo School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, NY 14215, USA.
authors.forename: Jahan
authors.initials: J
authors.lastname: Porhomayon
authors.forename: Peter
authors.initials: P
authors.lastname: Papadakos
authors.forename: Nader D
authors.initials: ND
authors.lastname: Nader