title: Kinetic resolution of nitrogen heterocycles with a reusable polymer-supported reagent.
abstract: Shake it up baby! Simply shaking a polymer-supported reagent and the racemic amine at room temperature kinetically resolves a broad range of N-heterocycles with good selectivity. The polymer-supported reagents are robust, easy to regenerate, and can be reused dozens of times. Cleavable acyl groups can be used to give access to both amine enantiomers in a single resolution.
authors.affiliation: Laboratorium für Organische Chemie, Department of Chemistry and Applied Biosciences, ETH-Zürich, Wolfgang-Pauli-Strasse 10, 8093 Zürich, Switzerland.
authors.forename: Imants
authors.initials: I
authors.lastname: Kreituss
authors.forename: Yuta
authors.initials: Y
authors.lastname: Murakami
authors.forename: Michael
authors.initials: M
authors.lastname: Binanzer
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Bode