title: Complex synchronous behavior in interneuronal networks with delayed inhibitory and fast electrical synapses.
abstract: Networks of fast-spiking interneurons are crucial for the generation of neural oscillations in the brain. Here we study the synchronous behavior of interneuronal networks that are coupled by delayed inhibitory and fast electrical synapses. We find that both coupling modes play a crucial role by the synchronization of the network. In addition, delayed inhibitory synapses affect the emerging oscillatory patterns. By increasing the inhibitory synaptic delay, we observe a transition from regular to mixed oscillatory patterns at a critical value. We also examine how the unreliability of inhibitory synapses influences the emergence of synchronization and the oscillatory patterns. We find that low levels of reliability tend to destroy synchronization and, moreover, that interneuronal networks with long inhibitory synaptic delays require a minimal level of reliability for the mixed oscillatory pattern to be maintained.
authors.affiliation: Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, People's Republic of China. dqguo07@gmail.com
authors.forename: Daqing
authors.initials: D
authors.lastname: Guo
authors.forename: Qingyun
authors.initials: Q
authors.lastname: Wang
authors.forename: Matjaž
authors.initials: M
authors.lastname: Perc
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D001683:Biological Clocks / Q000502:physiology*; D003198:Computer Simulation; D003344:Cortical Synchronization / Q000502:physiology*; D006801:Humans; D007395:Interneurons / Q000502:physiology*; D008959:Models, Neurological; D009433:Neural Inhibition / Q000502:physiology*; D013569:Synapses / Q000502:physiology*