title: Neurological disorders associated with glutamic acid decarboxylase antibodies: a Brazilian series.
abstract: Neurological disorders associated with glutamic acid decarboxylase (GAD) antibodies are rare pleomorphic diseases of uncertain cause, of which stiff-person syndrome (SPS) is the best-known. Here, we described nine consecutive cases of neurological disorders associated with anti-GAD, including nine patients with SPS and three cases with cerebellar ataxia. Additionally, four had hypothyroidism, three epilepsy, two diabetes mellitus and two axial myoclonus.
authors.affiliation: Movement Disorders Unit, Neurology Service, Internal Medicine Department, Hospital de Clínicas, Universidade Federal do Paraná (UFPR), Curitiba PR, Brazil.
authors.forename: Maurício
authors.initials: M
authors.lastname: Fernandes
authors.forename: Renato P
authors.initials: RP
authors.lastname: Munhoz
authors.forename: Paulo Eduardo Mestrinelli
authors.initials: PE
authors.lastname: Carrilho
authors.forename: Walter O
authors.initials: WO
authors.lastname: Arruda
authors.forename: Paulo J
authors.initials: PJ
authors.lastname: Lorenzoni
authors.forename: Rosana H
authors.initials: RH
authors.lastname: Scola
authors.forename: Lineu César
authors.initials: LC
authors.lastname: Werneck
authors.forename: Hélio A G
authors.initials: HA
authors.lastname: Teive
mesh_terms: D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000097:blood*; D001938:Brazil; D002524:Cerebellar Ataxia / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000276:immunology*; D002648:Child; D004568:Electrodiagnosis / Q000379:methods; D005260:Female; D005968:Glutamate Decarboxylase / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010295:Parietal Cells, Gastric / Q000276:immunology; D016750:Stiff-Person Syndrome / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000276:immunology*; D055815:Young Adult
chemical_list: D000906:Antibodies; D005968:Glutamate Decarboxylase