title: Multi-component synthesis of 2-amino-6-(alkyllthio)pyridine-3,5-dicarbonitriles using Zn(II) and Cd(II) metal-organic frameworks (MOFs) under solvent-free conditions.
abstract: Multi-component synthesis 2-amino-3,5-dicarbonitrile-6-thio-pyridines has been developed by using the reaction of aldehydes, malononitrile, and thiophenols in the presence of a Zn (II) or a Cd(II) metal-organic framework (MOF) as the heterogeneous catalyst. This protocol tolerates different functional groups on the substrates and does not require the use of any organic solvent. Moreover, the Zn(II) and Cd (II) MOF catalysts can be recovered and reused for a number of runs without loss of activity.
authors.affiliation: Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249-0698.
authors.forename: Muralidhara
authors.initials: M
authors.lastname: Thimmaiah
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.forename: Sridhar
authors.initials: S
authors.lastname: Regati
authors.forename: Banglin
authors.initials: B
authors.lastname: Chen
authors.forename: John Cong-Gui
authors.initials: JC
authors.lastname: Zhao