title: Conflict of interests: multiple signal peptides with diverging goals.
abstract: Peptide signal sequences attached to or embedded into a core protein sequence control its cellular localization and several post-translational modifications. However, misleading or cumbersome results may be generated when expressing recombinant proteins with modified signal peptides or single domains of larger proteins.
authors.affiliation: University of Nova Gorica (UNG), PO Box 301, Rožna Dolina (Nova Gorica) 5000, Slovenia.
authors.forename: Annunziata
authors.initials: A
authors.lastname: Venuto
authors.forename: Ario
authors.initials: A
authors.lastname: de Marco
mesh_terms: D006367:HeLa Cells; D006801:Humans; D011499:Protein Processing, Post-Translational / Q000235:genetics*; D021382:Protein Sorting Signals / Q000235:genetics*; D016271:Proto-Oncogene Proteins c-myc / Q000235:genetics / Q000378:metabolism; D011994:Recombinant Proteins / Q000378:metabolism; D015398:Signal Transduction
chemical_list: C489427:MYC protein, human; D021382:Protein Sorting Signals; D016271:Proto-Oncogene Proteins c-myc; D011994:Recombinant Proteins