title: Eosinophilic enteritis: efficiency of the 13C-acetate breath test for assessing the disease activity.
abstract: Few clinical studies have so far focused on gastrointestinal motility in patients with eosinophilic gastroenteritis. A 29-year-old man was evaluated for epigastralgia of unknown origin. A histopathological examination of biopsy specimens from the duodenum revealed numerous eosinophilic infiltrations. Eosinophilic enteritis was therefore diagnosed. The patient received oral prednisolone and his symptoms improved. Both at the onset and at relapse of the disease, the maximal (13)CO(2) excretion time (T(max)) of (13)C-acetate breath test was noted to have increased levels of excretion. Recovery of this parameter was observed in parallel with clinical improvements after treatments. This is the first report of a case of eosinophilic enteritis in which the (13)C-acetate breath test was effective for assessing the disease activity and evaluating the effectiveness of treatment.
authors.affiliation: Department of General Medicine, Nagasaki University Hospital, Japan.
authors.forename: Aya
authors.initials: A
authors.lastname: Yoda
authors.forename: Fuminao
authors.initials: F
authors.lastname: Takeshima
authors.forename: Koichiro
authors.initials: K
authors.lastname: Kadota
authors.forename: Keita
authors.initials: K
authors.lastname: Inoue
authors.forename: Seiko
authors.initials: S
authors.lastname: Nakamichi
authors.forename: Tomayoshi
authors.initials: T
authors.lastname: Hayashi
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Nakao
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Oozono
mesh_terms: D000085:Acetates; D000328:Adult; D001706:Biopsy; D001944:Breath Tests; D002247:Carbon Isotopes; D004386:Duodenum / Q000473:pathology; D004751:Enteritis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*; D004802:Eosinophilia / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*; D005746:Gastric Emptying; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000085:Acetates; D002247:Carbon Isotopes; D005938:Glucocorticoids; D011239:Prednisolone