title: Efficacy of intradermal radiofrequency combined with autologous platelet-rich plasma in striae distensae: a pilot study.
abstract: BACKGROUND
  Different types of laser have recently been reported as effective tools of treatment in striae distensae. Although fractional photothermolysis is effective for striae distensae, post-inflammatory hyperpigmentation is a major concern and common complication. There are no reports of the effects of using an intradermal radiofrequency (RF) device in striae distensae. Autologous platelet-rich plasma (PRP) is an effective treatment known for its wound-healing effects.
  
  
  METHODS
  Nineteen Asian female patients with striae distensae were enrolled in this study. Three sessions of intradermal RF (1134-kHz frequency, 12-W power, 26-G electrode size) combined with autologous PRP were performed in each patient at intervals of four weeks. Patients were evaluated subjectively by the investigators and by themselves.
  
  
  RESULTS
  Evaluation of clinical results at four weeks after treatment showed that only one (5.3%) of the 19 patients achieved excellent improvement, whereas seven (36.8%) demonstrated marked improvement, six (31.6%) showed moderate improvement, and five (26.3%) showed mild improvement. None of the patients showed worsening of striae distensae. A total of 63.2% of patients reported they were "satisfied" or "very satisfied" with the degree of overall improvement.
  
  
  CONCLUSIONS
  Intradermal RF combined with autologous PRP appears to be an effective treatment for striae distensae.
authors.affiliation: Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.
authors.forename: In Su
authors.initials: IS
authors.lastname: Kim
authors.forename: Kui Young
authors.initials: KY
authors.lastname: Park
authors.forename: Beom Joon
authors.initials: BJ
authors.lastname: Kim
authors.forename: Myeung Nam
authors.initials: MN
authors.lastname: Kim
authors.forename: Chan Woong
authors.initials: CW
authors.lastname: Kim
authors.forename: Sung Eun
authors.initials: SE
authors.lastname: Kim
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D017060:Patient Satisfaction; D010865:Pilot Projects; D053657:Platelet-Rich Plasma; D000078702:Radiofrequency Therapy; D057896:Striae Distensae / Q000532:radiotherapy / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult