title: Observation of multiphoton-induced fluorescence from graphene oxide nanoparticles and applications in in vivo functional bioimaging.
abstract: Lightening organelles: A femtosecond laser can excite multiphoton-induced luminescence of graphene oxide nanoparticles. The flow, distributions, and clearance of intravenously injected GO-PEG nanoparticles in the blood vessel of mice could be observed clearly by two-photon imaging. The 3D distribution of microinjected GO-PEG nanoparticles in a mice brain could also be reconstructed with two-photon microscopy.
authors.affiliation: Centre for Optical and Electromagnetic Research, Zhejiang Provincial Key Laboratory for Sensing Technologies, Zhejiang University, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Qian
authors.forename: Dan
authors.initials: D
authors.lastname: Wang
authors.forename: Fu-Hong
authors.initials: FH
authors.lastname: Cai
authors.forename: Wang
authors.initials: W
authors.lastname: Xi
authors.forename: Li
authors.initials: L
authors.lastname: Peng
authors.forename: Zhen-Feng
authors.initials: ZF
authors.lastname: Zhu
authors.forename: Hao
authors.initials: H
authors.lastname: He
authors.forename: Ming-Lie
authors.initials: ML
authors.lastname: Hu
authors.forename: Sailing
authors.initials: S
authors.lastname: He
mesh_terms: D000818:Animals; D003952:Diagnostic Imaging / Q000379:methods; D005453:Fluorescence; D006108:Graphite / Q000737:chemistry*; D008163:Luminescent Measurements / Q000379:methods; D051379:Mice; D018613:Microscopy, Confocal / Q000379:methods; D053758:Nanoparticles / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*; D017785:Photons; D014162:Transfection
chemical_list: D010087:Oxides; D006108:Graphite