title: [Some aspects of molecular bases of keloid formation].
abstract: Keloid scarring, also known as keloid disease, is a benign, locally aggressive fibroproliferative scar overgrowth that expands with involvement of adjacent healthy skin. The pathogenesis of keloid disease has not been fully elucidated. In recent years, many reports have been published that unequivocally reveal genetic predispositions to keloid formation. Basing on the available literature, the authors present the most recent research on some aspects of molecular bases of keloid scarring.
authors.affiliation: Klinika Chorób Skórnych i Wenerycznych Pomorskiego Uniwersytetu Medycznego w Szczecinie al. Powstańców Wlkp. 72, 70-111 Szczecin.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Pastuszak-Gabinowska
authors.forename: Jarosław
authors.initials: J
authors.lastname: Peregud-Pogorzelski
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Łuksza
authors.forename: Piotr
authors.initials: P
authors.lastname: Sznelewski
authors.forename: Andrzej
authors.initials: A
authors.lastname: Brodkiewicz
mesh_terms: D017209:Apoptosis / Q000235:genetics; D016207:Cytokines / Q000235:genetics / Q000378:metabolism; D020022:Genetic Predisposition to Disease; D006801:Humans; D007627:Keloid / Q000235:genetics*; D009154:Mutation; D011110:Polymorphism, Genetic; D016392:Proto-Oncogene Proteins pp60(c-src) / Q000235:genetics / Q000378:metabolism
chemical_list: D016207:Cytokines; C085377:MATK protein, human; D016392:Proto-Oncogene Proteins pp60(c-src)