title: Pain is not associated with worse office-based buprenorphine treatment outcomes.
abstract: Physical pain is common among individuals seeking treatment for opioid dependence. Pain may negatively impact addiction treatment. The authors prospectively studied opioid-dependent individuals initiating office-based buprenorphine treatment, comparing buprenorphine treatment outcomes (treatment retention and opioid use) among participants with and without pain (baseline pain or persistent pain). Among 82 participants, 60% reported baseline pain and 38% reported persistent pain. Overall, treatment retention was 56% and opioid use decreased from 89% to 26% over 6 months. In multivariable analyses, the authors found no association between pain and buprenorphine treatment outcomes. Opioid-dependent individuals with and without pain can achieve similar success with buprenorphine treatment.
authors.affiliation: Albert Einstein College of Medicine, Bronx, New York 10467, USA. adfox@montefiore.org
authors.forename: Aaron D
authors.initials: AD
authors.lastname: Fox
authors.forename: Nancy L
authors.initials: NL
authors.lastname: Sohler
authors.forename: Joanna L
authors.initials: JL
authors.lastname: Starrels
authors.forename: Yuming
authors.initials: Y
authors.lastname: Ning
authors.forename: Angela
authors.initials: A
authors.lastname: Giovanniello
authors.forename: Chinazo O
authors.initials: CO
authors.lastname: Cunningham
mesh_terms: D002047:Buprenorphine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D055118:Medication Adherence / Q000523:psychology; D008875:Middle Aged; D009292:Narcotic Antagonists / Q000627:therapeutic use*; D058850:Opiate Substitution Treatment / Q000379:methods / Q000523:psychology*; D009293:Opioid-Related Disorders / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D010146:Pain / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D011320:Primary Health Care / Q000706:statistics & numerical data*; D016896:Treatment Outcome; D016903:Drug Monitoring
chemical_list: D009292:Narcotic Antagonists; D002047:Buprenorphine