title: Bias in comparative effectiveness studies due to regional variation in medical practice intensity: a legitimate concern, or much ado about nothing?
authors.affiliation: Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1620 Tremont Street, Boston, MA 02120, USA. khuybrechts@partners.org
authors.forename: Krista F
authors.initials: KF
authors.lastname: Huybrechts
authors.forename: John D
authors.initials: JD
authors.lastname: Seeger
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Rothman
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Glynn
authors.forename: Jerry
authors.initials: J
authors.lastname: Avorn
authors.forename: Sebastian
authors.initials: S
authors.lastname: Schneeweiss
mesh_terms: D015982:Bias; D057186:Comparative Effectiveness Research / Q000379:methods* / Q000592:standards / Q000706:statistics & numerical data; D019983:Guideline Adherence; D054625:Healthcare Disparities / Q000592:standards / Q000706:statistics & numerical data; D006801:Humans; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000592:standards / Q000706:statistics & numerical data; D019984:Quality Indicators, Health Care / Q000592:standards / Q000706:statistics & numerical data; D015203:Reproducibility of Results; D012107:Research Design / Q000592:standards / Q000706:statistics & numerical data; D012111:Residence Characteristics / Q000706:statistics & numerical data; D014481:United States