title: [A case of pathological complete response after chemotherapy for liver metastasis with subcapsular hemorrhage from gastric cancer:].
abstract: A57 years old man with gastric cancer underwent distal gastrectomy (pT3N1M0, pStage II B). Three months after gastric resection, he was admitted to our hospital because of acute right dorsal pain. Abdominal computed tomography showed multiple liver tumors with subcapsular hemorrhage. He was diagnosed as multiple liver metastases from gastric cancer. We judged liver tumors to be unresectable and decided to start systemic chemotherapy with S-1 and cisplatin (CDDP) because he was hemodynamically stable. After 8 courses of chemotherapy, the liver tumors were markedly reduced and judged as clinical partial response. Left hepatectomy and S5, S6, S7 partial hepatectomy for liver metastasis was performed. Histopathological examination of the resected specimen revealed no cancer cell in the liver, suggesting a pathologically complete response. We consider that systemic chemotherapy is one of the effective treatments for unresectable liver metastasis with subcapsular hemorrhage from gastric metastasis.
authors.affiliation: Divison of Gastric Surgery, Shizuoka Cancer Center.
authors.forename: Hironobu
authors.initials: H
authors.lastname: Goto
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tanizawa
authors.forename: Etsuro
authors.initials: E
authors.lastname: Bando
authors.forename: Masanori
authors.initials: M
authors.lastname: Tokunaga
authors.forename: Taiichi
authors.initials: T
authors.lastname: Kawamura
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Kanemoto
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Uesaka
authors.forename: Takeshi
authors.initials: T
authors.lastname: Aramaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yasui
authors.forename: Masanori
authors.initials: M
authors.lastname: Terashima
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004338:Drug Combinations; D017809:Fatal Outcome; D005743:Gastrectomy; D006470:Hemorrhage / Q000209:etiology*; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010094:Oxonic Acid / Q000008:administration & dosage; D016879:Salvage Therapy; D013274:Stomach Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin