title: Compliance to micronutrient supplementation in children 3 to 24 months of age from a semi-rural community in Mexico.
abstract: OBJECTIVE
  To identify associated factors to compliance for multiple micronutrient (MM) or iron and vitamin A (IVITA) supplementation, in children (3 to 24 months old).
  
  
  METHODS
  A database (n=465 children) from a randomized, controlled, clinical trial, carried out in a semi-rural setting in Mexico, was analyzed. The compliance rate of MM and IVITA supplements was calculated. Adequate compliance rate (AC>80%), and its association with children and households characteristics, was determined.
  
  
  RESULTS
  The compliance mean was high (MM:78.2%, IVITA:80.1%; p<0.05). The odds of AC were 59% greater in the children of IVITA than with MM group, although the estimate was only marginally significant (p=0.052). Maternal education (p<0.001), child birth weight (p=0.003), and children with cough (p<0.001) or fever (p=0.024) were significantly associated with AC and significantly marginal was maternal indigenous (p=0.071).
  
  
  CONCLUSIONS
  The high AC was consistent with others efficacy studies. More research is needed to document physiological, cultural, social and operative factors affecting compliance with supplementation.
authors.affiliation: Secretaría de Salud de Nayarit, Tepic, Nayarit, México.
authors.forename: Fernando
authors.initials: F
authors.lastname: López-Flores
authors.forename: Lynnette Marie
authors.initials: LM
authors.lastname: Neufeld
authors.forename: Daniela
authors.initials: D
authors.lastname: Sotres-Álvarez
authors.forename: Armando
authors.initials: A
authors.lastname: García-Guerra
authors.forename: Usha
authors.initials: U
authors.lastname: Ramakrishnan
mesh_terms: D000328:Adult; D001724:Birth Weight; D001942:Breast Feeding; D003371:Cough / Q000453:epidemiology; D016208:Databases, Factual / Q000706:statistics & numerical data; D003967:Diarrhea / Q000453:epidemiology; D019587:Dietary Supplements; D004311:Double-Blind Method; D004522:Educational Status; D005260:Female; D005334:Fever / Q000453:epidemiology; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007198:Indians, North American / Q000706:statistics & numerical data; D007223:Infant; D007225:Infant Food; D007501:Iron / Q000008:administration & dosage; D008297:Male; D055118:Medication Adherence / Q000208:ethnology; D008800:Mexico; D018977:Micronutrients / Q000008:administration & dosage*; D009035:Mothers / Q000706:statistics & numerical data; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data; D012307:Risk Factors; D012424:Rural Population / Q000706:statistics & numerical data; D012959:Socioeconomic Factors; D014801:Vitamin A / Q000008:administration & dosage; D016903:Drug Monitoring
chemical_list: D006454:Hemoglobins; D018977:Micronutrients; D014801:Vitamin A; D007501:Iron