title: Measuring glomerular filtration rate in acute kidney injury: yes, but not yet.
abstract: Acute kidney injury has become a major focus for nephrologists and critical care physicians. The development of structural biomarkers is proceeding, but the results to date have been disappointing. The use of a shortened creatinine clearance as a functional acute kidney injury biomarker is not new but has not been compared with that of other diagnostic approaches. A rapid, repeatable, and accurate measured glomerular filtration rate would be the gold standard for a functional biomarker and is not far off.
authors.forename: Bruce A
authors.initials: BA
authors.lastname: Molitoris
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood*; D003404:Creatinine / Q000097:blood*; D016638:Critical Illness / Q000628:therapy*; D005260:Female; D006801:Humans; D007677:Kidney Function Tests / Q000379:methods*; D008297:Male
chemical_list: D003404:Creatinine