title: Image artifacts from MR-based attenuation correction in clinical, whole-body PET/MRI.
abstract: OBJECTIVE
  Integrated whole-body PET/MRI tomographs have become available. PET/MR imaging has the potential to supplement, or even replace combined PET/CT imaging in selected clinical indications. However, this is true only if methodological pitfalls and image artifacts arising from novel MR-based attenuation correction (MR-AC) are fully understood.
  
  
  RESULTS
  Here we present PET/MR image artifacts following routine MR-AC, as most frequently observed in clinical operations of an integrated whole-body PET/MRI system.
  
  
  CONCLUSIONS
  A clinical adoption of integrated PET/MRI should entail the joint image display and interpretation of MR data, MR-based attenuation maps and uncorrected plus attenuation-corrected PET images in order to recognize potential pitfalls from MR-AC and to ensure clinically accurate image interpretation.
authors.affiliation: Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark. sune@pet.rh.dk
authors.forename: Sune H
authors.initials: SH
authors.lastname: Keller
authors.forename: Søren
authors.initials: S
authors.lastname: Holm
authors.forename: Adam E
authors.initials: AE
authors.lastname: Hansen
authors.forename: Bernhard
authors.initials: B
authors.lastname: Sattler
authors.forename: Flemming
authors.initials: F
authors.lastname: Andersen
authors.forename: Thomas L
authors.initials: TL
authors.lastname: Klausen
authors.forename: Liselotte
authors.initials: L
authors.lastname: Højgaard
authors.forename: Andreas
authors.initials: A
authors.lastname: Kjær
authors.forename: Thomas
authors.initials: T
authors.lastname: Beyer
mesh_terms: D000465:Algorithms; D016477:Artifacts; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18