title: Plasmablastic lymphoma of the larynx: report of two cases.
abstract: OBJECTIVE
  To report two cases of laryngeal plasmablastic lymphoma, a rare and relatively recently described form of non-Hodgkin's lymphoma. It has not previously been described in the larynx, nor associated with upper airway obstruction.
  
  
  METHODS
  We describe the clinicopathological features of two such cases in human immunodeficiency virus positive patients, and we discuss their unusual presentations and diagnostic features.
  
  
  CONCLUSIONS
  When evaluating a laryngeal tumour, plasmablastic lymphoma and other non-Hodgkin's lymphomata should be considered as differential diagnoses, particularly in the setting of a high prevalence of human immunodeficiency virus infection. Biopsy with detailed histopathological and immunohistochemical evaluation is recommended to ensure correct diagnosis and optimal management.
authors.affiliation: Division of Otorhinolaryngology, University of Cape Town, South Africa. katestephenson@doctors.org.uk
authors.forename: K
authors.initials: K
authors.lastname: Stephenson
authors.forename: S
authors.initials: S
authors.lastname: Peer
authors.forename: D
authors.initials: D
authors.lastname: Govender
authors.forename: J J
authors.initials: JJ
authors.lastname: Fagan
mesh_terms: D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D004724:Endoscopy; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000628:therapy; D016400:Lymphoma, Large-Cell, Immunoblastic / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010784:Photomicrography