title: Oleanane-type triterpenoid saponins from Xanthoceras sorbifolia Bunge.
abstract: Phytochemical analysis of the extract from the seed oil leavings of Xanthoceras sorbifolia Bunge led to the isolation of five new oleanane-type triterpeniod saponins, sorbifoliasides G-K (1-5). Their structures were elucidated on the basis of spectroscopic analysis and chemical derivatization. To our knowledge, compound 5 is the first example of a naturally occurring 3,28-O-bisdesmosic triterpenoid saponin with olefinic linkages at C12 and C15. The cytotoxicity of all compounds against ten selected human cancer cell lines was assayed.
authors.affiliation: Department of Natural Products Chemistry, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shengyang 110016, People's Republic of China.
authors.forename: Lili
authors.initials: L
authors.lastname: Yu
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Tang
authors.forename: Lixia
authors.initials: L
authors.lastname: Chen
authors.forename: Miaomiao
authors.initials: M
authors.lastname: Wang
authors.forename: Junfeng
authors.initials: J
authors.lastname: Jian
authors.forename: Shijie
authors.initials: S
authors.lastname: Cao
authors.forename: Xiaobing
authors.initials: X
authors.lastname: Wang
authors.forename: Ning
authors.initials: N
authors.lastname: Kang
authors.forename: Feng
authors.initials: F
authors.lastname: Qiu
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D006801:Humans; D015394:Molecular Structure; D029631:Sapindaceae / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D012503:Saponins; D014315:Triterpenes