title: Assessing the safety of influenza vaccination in specific populations: children and the elderly.
abstract: Comprehensive monitoring of the safety of influenza vaccines remains a public health priority, particularly as immunization coverage increases across different age groups at the global level. In this review, the authors provide state-of-the-art knowledge on the safety of influenza immunization among children and the elderly. The authors review the safety information in each group separately for inactivated and live attenuated influenza vaccines. Adverse events of special concern including febrile seizure, narcolepsy, asthma and Guillain-Barré syndrome are covered under specific considerations. The authors discuss the current status of the field, particularly the use of new technologies for influenza vaccines and their potential safety profile.
authors.affiliation: Kaiser Permanente Vaccine Study Center, One Kaiser Plaza, Floor 16, Oakland, CA 94612, USA. ali.x.rowhani-rahbar@kp.org
authors.forename: Ali
authors.initials: A
authors.lastname: Rowhani-Rahbar
authors.forename: Nicola P
authors.initials: NP
authors.lastname: Klein
authors.forename: Roger
authors.initials: R
authors.lastname: Baxter
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems / Q000706:statistics & numerical data; D000368:Aged; D001249:Asthma / Q000276:immunology / Q000821:virology; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009980:Influenza A virus / Q000276:immunology / Q000472:pathogenicity; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000009:adverse effects* / Q000276:immunology; D007251:Influenza, Human / Q000517:prevention & control*; D009290:Narcolepsy / Q000276:immunology / Q000821:virology; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D003294:Seizures, Febrile / Q000276:immunology / Q000821:virology; D014611:Vaccination / Q000009:adverse effects* / Q000379:methods; D062690:Vaccines, Live, Unattenuated / Q000008:administration & dosage / Q000276:immunology
chemical_list: D007252:Influenza Vaccines; D062690:Vaccines, Live, Unattenuated