title: Cerebrospinal fluid findings in children with fever-associated status epilepticus: results of the consequences of prolonged febrile seizures (FEBSTAT) study.
abstract: This prospective multicenter study of 200 patients with fever-associated status epilepticus (FSE), of whom 136 underwent a nontraumatic lumbar puncture, confirms that FSE rarely causes cerebrospinal fluid (CSF) pleocytosis. CSF glucose and protein levels were unremarkable. Temperature, age, seizure focality, and seizure duration did not affect results. CSF pleocytosis should not be attributed to FSE.
authors.affiliation: Department of Pediatrics, Children's Hospital of The King's Daughters and Eastern Virginia Medical School, Norfolk, VA, USA. matthew.frank@chkd.org
authors.forename: L Matthew
authors.initials: LM
authors.lastname: Frank
authors.forename: Shlomo
authors.initials: S
authors.lastname: Shinnar
authors.forename: Dale C
authors.initials: DC
authors.lastname: Hesdorffer
authors.forename: Ruth C
authors.initials: RC
authors.lastname: Shinnar
authors.forename: John M
authors.initials: JM
authors.lastname: Pellock
authors.forename: William
authors.initials: W
authors.lastname: Gallentine
authors.forename: Douglas R
authors.initials: DR
authors.lastname: Nordli
authors.forename: Leon G
authors.initials: LG
authors.lastname: Epstein
authors.forename: Solomon L
authors.initials: SL
authors.lastname: Moshé
authors.forename: Darrell V
authors.initials: DV
authors.lastname: Lewis
authors.forename: Shumei
authors.initials: S
authors.lastname: Sun
mesh_terms: D015415:Biomarkers / Q000134:cerebrospinal fluid; D002556:Cerebrospinal Fluid Proteins / Q000378:metabolism; D002648:Child; D005947:Glucose / Q000134:cerebrospinal fluid; D006801:Humans; D007962:Leukocytes / Q000378:metabolism; D007964:Leukocytosis / Q000134:cerebrospinal fluid / Q000209:etiology; D011446:Prospective Studies; D003294:Seizures, Febrile / Q000134:cerebrospinal fluid* / Q000503:physiopathology; D013129:Spinal Puncture; D013226:Status Epilepticus / Q000134:cerebrospinal fluid* / Q000209:etiology
chemical_list: D015415:Biomarkers; D002556:Cerebrospinal Fluid Proteins; D005947:Glucose