title: [Long-term use of silicone oil: indications and tolerance].
abstract: OBJECTIVE
  The aim of this study was to analyze the indications and the effect of permanently maintaining silicone oil in the treatment of certain cases of vitreoretinal pathology.
  
  
  METHODS
  Twenty-seven cases seen from January 2002 to December 2008 were retrospectively studied. Silicone oil was kept in the eyes for more than 2years. The surgical file was analyzed in all cases. The evaluation criteria were ocular pressure, emulsification, cataract, corneal dystrophy, and the functional response of the retina and optic nerve. Ultrasound echography (12 MHz), magnetic resonance imaging, and electrophysiological explorations (visual evoked potential and electroretinography) were performed.
  
  
  RESULTS
  Twenty-seven eyes of 27 patients were included in this study. The main reasons for maintaining long-term silicone oil are recurrent vitreous hemorrhage, retinal detachment with severe proliferative vitreoretinopathy, and penetrating injury. The patients were distributed into two groups: group 1 included patients with both functional and anatomic failure, group 2 patients had achieved ambulatory vision. Follow-up ranged from 27 to 72months. Cataract incidence was approximately 91% in group 2. Emulsification was noted without high pressure in 50% of the cases in group 1. High pressure averaged 31.8% in group 2. Keratopathy was observed in 9% of the cases in group 2. Intraorbital migration of silicone oil was found in one case. The visual field was improved in 77% of the cases in group 2.
  
  
  CONCLUSIONS
  This study provided interesting insights into certain clinical situations in which silicone oil has to be maintained permanently. The complications stem not only from the presence of silicone oil, but also from the preoperative status of the eye and the vitreoretinal surgery.
authors.affiliation: Service d'ophtalmologie, CHU Habib Bourguiba, 3029 Sfax, Tunisie. amira.trigui@tunet.tn
authors.forename: A
authors.initials: A
authors.lastname: Trigui
authors.forename: J
authors.initials: J
authors.lastname: Gharbi
authors.forename: S
authors.initials: S
authors.lastname: Hamdi
authors.forename: K H
authors.initials: KH
authors.lastname: Mahfoudh
authors.forename: J
authors.initials: J
authors.lastname: Feki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005128:Eye Diseases / Q000453:epidemiology / Q000601:surgery / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D012163:Retinal Detachment / Q000453:epidemiology / Q000601:surgery; D012189:Retrospective Studies; D012827:Silicone Oils / Q000009:adverse effects / Q000627:therapeutic use*; D013997:Time Factors; D014821:Vitrectomy / Q000534:rehabilitation; D018630:Vitreoretinopathy, Proliferative / Q000453:epidemiology / Q000601:surgery; D055815:Young Adult
chemical_list: D012827:Silicone Oils