title: Development of silver nanoparticle loaded antibacterial polymer mesh using plasma polymerization process.
abstract: Plasma polymerized polyacrylic acid (PPAA) was deposited on a polymer substrate, namely polyethylene terephthalate (PET) mesh, for entrapment of silver nanoparticle (Ag-NP) in order to achieve antibacterial property to the material. Carboxylic groups of PPAA act as anchor as well as capping and stabilizing agents for Ag-NPs synthesized by chemical reduction method using NaBH(4) as a reducing agent. Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy (XPS), and water contact angle analysis were used to characterize the PPAA coatings. The Ag-NPs loaded polymer samples were characterized by UV-visible spectroscopy, field emission scanning electron microscopy, energy dispersive X-ray, and XPS techniques. XPS analysis showed ~1.0 at.% loading of Ag-NPs on to the PPAA-PET-mesh, which was composed of 79% zero-valent (Ag°) and 21% oxidized nano-Ag (Ag(+) ). The plasma processed PET meshes samples were tested for antibacterial activity against two bacterial strains, namely Staphylococcus aureus (Gram positive) and Escherichia coli (Gram negative). Qualitative and quantitative tests showed that silver containing PPAA-PET meshes exhibit excellent antibacterial property against the tested bacteria with percent reduction of bacterial concentration >99%, compared to the untreated PET mesh.
authors.affiliation: Laboratoire de Génie des Procédés Plasmas et Traitement de Surface, Université Pierre et Marie Curie, ENSCP-Chimie Paris Tech, Paris, France. vkrawat75@gmail.com
authors.forename: Virendra
authors.initials: V
authors.lastname: Kumar
authors.forename: Claude
authors.initials: C
authors.lastname: Jolivalt
authors.forename: Jerome
authors.initials: J
authors.lastname: Pulpytel
authors.forename: Reza
authors.initials: R
authors.lastname: Jafari
authors.forename: Farzaneh
authors.initials: F
authors.lastname: Arefi-Khonsari
mesh_terms: D000180:Acrylic Resins / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D004926:Escherichia coli / Q000254:growth & development*; D053768:Metal Nanoparticles / Q000737:chemistry*; D011093:Polyethylene Terephthalates / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D012834:Silver / Q000737:chemistry / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000254:growth & development*
chemical_list: D000180:Acrylic Resins; D000900:Anti-Bacterial Agents; D020099:Coated Materials, Biocompatible; D011093:Polyethylene Terephthalates; D012834:Silver; C006903:carbopol 940