title: Mechanisms and prediction of aortic regurgitation after TAVI.
abstract: It has been demonstrated that moderate to severe paravalvular leak (PVL) after transcatheter aortic valve implantation (TAVI) procedures are related to impaired long-term prognosis. Anatomical and procedural factors influence the frequency and severity of PVL. Anatomical predictors of this complication are: annulus dimensions and shape, calcium distribution, angle between the ascending aorta axis and the left ventricular outflow tract (LVOT-AO). Procedural predictors: prosthesis-size-annulus mismatch, valve depth deployment and the acquired experience of the centre. An effort has to be made to optimise valve sizing and deployment.
authors.affiliation: Cardiac Thoracic and Vascular Department, University of Pisa, Pisa, Italy. as.petronio@gmail.com
authors.forename: Anna Sonia
authors.initials: AS
authors.lastname: Petronio
authors.forename: Cristina
authors.initials: C
authors.lastname: Giannini
authors.forename: Marco
authors.initials: M
authors.lastname: De Carlo
mesh_terms: D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000209:etiology*; D001024:Aortic Valve Stenosis / Q000175:diagnosis / Q000628:therapy*; D006328:Cardiac Catheterization / Q000009:adverse effects* / Q000295:instrumentation; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods; D006801:Humans; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012307:Risk Factors; D012720:Severity of Illness Index; D016896:Treatment Outcome