title: Methanol and ethylene glycol intoxication.
abstract: Accidental or intentional ingestion of substances containing methanol and ethylene glycol can result in death, and some survivors are left with blindness, renal dysfunction, and chronic brain injury. However, even in large ingestions, a favorable outcome is possible if the patient arrives at the hospital early enough and the poisoning is identified and appropriately treated in a timely manner. This review covers the common circumstances of exposure, the involved toxic mechanisms, and the clinical manifestations, laboratory findings, and treatment of methanol and ethylene glycol intoxication.
authors.affiliation: College of Physicians and Surgeons, Columbia University, 116 Broadway, New York, NY 10027, USA. james.kruse@bassett.org
authors.forename: James A
authors.initials: JA
authors.lastname: Kruse
mesh_terms: D015746:Abdominal Pain / Q000139:chemically induced; D002318:Cardiovascular Diseases / Q000139:chemically induced; D019963:Clinical Chemistry Tests; D019855:Ethylene Glycol / Q000378:metabolism / Q000506:poisoning*; D006801:Humans; D000432:Methanol / Q000378:metabolism / Q000506:poisoning*; D009325:Nausea / Q000139:chemically induced; D009422:Nervous System Diseases / Q000139:chemically induced; D011041:Poisoning / Q000150:complications / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D012120:Respiration Disorders / Q000139:chemically induced; D014786:Vision Disorders / Q000139:chemically induced; D014839:Vomiting / Q000139:chemically induced
chemical_list: D019855:Ethylene Glycol; D000432:Methanol