title: Alveolar soft part sarcoma metastasized to both the skull and the brain.
abstract: Alveolar soft part sarcoma (ASPS) with skull and brain metastases is extremely rare. A 53-year-old patient diagnosed as skull metastasis of ASPS visited our clinic complaining of an outgrowing scalp mass in spite of radiation therapy. Past medical history revealed that the patient had been diagnosed and treated for ASPS of the thigh 4 years ago. Magnetic resonance imaging revealed a hyperintense ovoid mass on the T2-weighted image, an isointense on the T1-weighted image, and a homogeneous enhanced mass with gadolinium. Another small-sized enhanced mass with mild peritumoral swelling was found at the deep white matter of the left frontal lobe. A gross total resection of the skull lesion with cranioplasty was performed for the surgical defect. A histologic examination of the specimens revealed metastatic ASPS involving the skull. Surgery with a total removal of the lesions may be effective for improving a patient's symptoms especially from neurological dysfunction.
authors.affiliation: Department of Neurosurgery, Yeungnam University College of Medicine, Daegu, Korea.
authors.forename: Tae-Hee
authors.initials: TH
authors.lastname: Shin
authors.forename: Young-Jin
authors.initials: YJ
authors.lastname: Jung
authors.forename: Oh-Lyong
authors.initials: OL
authors.lastname: Kim
authors.forename: Min-Su
authors.initials: MS
authors.lastname: Kim