title: Successful treatment of reactive hypoglycemia secondary to late dumping syndrome using miglitol.
abstract: We herein describe a 59-year-old woman who had undergone a total gastrectomy for gastric carcinoma and suffered from postprandial hypoglycemia characterized by a loss of consciousness and spasms. She was diagnosed with reactive hypoglycemia and treated with nutrition therapy, but the frequency and severity of the hypoglycemic episodes did not decrease. She was subsequently treated successfully with miglitol, an alpha-glucosidase inhibitor (α-GI) taken twice a day; other α-GIs (acarbose and voglibose) were not effective. In conclusion, the administration of miglitol was effective for preventing reactive hypoglycemia secondary to late dumping syndrome.
authors.affiliation: Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Japan.
authors.forename: Yukari
authors.initials: Y
authors.lastname: Fujita
authors.forename: Daisuke
authors.initials: D
authors.lastname: Tamada
authors.forename: Junji
authors.initials: J
authors.lastname: Kozawa
authors.forename: Yoko
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Shugo
authors.initials: S
authors.lastname: Sasaki
authors.forename: Tetsuhiro
authors.initials: T
authors.lastname: Kitamura
authors.forename: Tetsuyuki
authors.initials: T
authors.lastname: Yasuda
authors.forename: Norikazu
authors.initials: N
authors.lastname: Maeda
authors.forename: Michio
authors.initials: M
authors.lastname: Otsuki
authors.forename: Kohei
authors.initials: K
authors.lastname: Okita
authors.forename: Hiromi
authors.initials: H
authors.lastname: Iwahashi
authors.forename: Hideaki
authors.initials: H
authors.lastname: Kaneto
authors.forename: Tohru
authors.initials: T
authors.lastname: Funahashi
authors.forename: Akihisa
authors.initials: A
authors.lastname: Imagawa
authors.forename: Iichiro
authors.initials: I
authors.lastname: Shimomura
mesh_terms: D017485:1-Deoxynojirimycin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004377:Dumping Syndrome / Q000150:complications*; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D005260:Female; D065089:Glycoside Hydrolase Inhibitors; D006801:Humans; D007003:Hypoglycemia / Q000188:drug therapy* / Q000209:etiology*; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D004791:Enzyme Inhibitors; D065089:Glycoside Hydrolase Inhibitors; C045621:miglitol; D017485:1-Deoxynojirimycin