title: Update on pharmacology of antiplatelets, anticoagulants, and thrombolytics.
abstract: Understanding of the pharmacology of thrombolytics, anticoagulants, and antiplatelets is critical to performing safe and effective endovascular therapy for acute ischemic therapy. This is a basic review of the clinical pharmacologic data on the anticoagulants, antiplatelets, and fibrinolytic agents most commonly used in the treatment of stroke and in the neurointerventional suite.
authors.affiliation: Cleveland Clinic Stroke Program, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Esteban
authors.initials: E
authors.lastname: Cheng-Ching
authors.forename: Edgar A
authors.initials: EA
authors.lastname: Samaniego
authors.forename: Bharath Reddy
authors.initials: BR
authors.lastname: Naravetla
authors.forename: Osama O
authors.initials: OO
authors.lastname: Zaidat
authors.forename: Muhammad Shazam
authors.initials: MS
authors.lastname: Hussain
mesh_terms: D000818:Animals; D000925:Anticoagulants / Q000494:pharmacology* / Q000627:therapeutic use; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism; D005343:Fibrinolytic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D020521:Stroke / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D015912:Thrombolytic Therapy / Q000379:methods / Q000639:trends
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors