title: NF-κB and hypoxia: a double-edged sword in atherosclerosis.
abstract: This Commentary highlights the article by Fang et al, which describes novel mouse models of chronic intermittent hypoxia (CIH)-induced atherosclerosis, revealing that loss of the NF-κB p50 subunit increased atherosclerosis in the presence of CIH.
authors.affiliation: Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Xinghui
authors.initials: X
authors.lastname: Sun
authors.forename: Mark W
authors.initials: MW
authors.lastname: Feinberg
mesh_terms: D000818:Animals; D001057:Apolipoproteins E / Q000172:deficiency*; D050197:Atherosclerosis / Q000378:metabolism* / Q000473:pathology*; D005260:Female; D000860:Hypoxia / Q000378:metabolism* / Q000473:pathology*; D008297:Male; D052002:NF-kappa B p50 Subunit / Q000378:metabolism*
chemical_list: D001057:Apolipoproteins E; D052002:NF-kappa B p50 Subunit