title: Pd(0)-catalyzed decarboxylative coupling and tandem C-H arylation/decarboxylation for the synthesis of heteroaromatic biaryls.
abstract: An effective Pd(0) carbene complex was successfully employed in the decarboxylative coupling of the heteroaromatic carboxylic acids (imidazo[1,2-a]pyridine and isoxazole) with aryl halides. For carboxyindoles, either decarboxylative coupling or tandem C-H arylation and decarboxylation occurred, leading to the formation of C2-monoarylated indoles.
authors.affiliation: Department of Chemistry, National Changhua University of Education, Changhua 50058, Taiwan, R.O.C.
authors.forename: Debkumar
authors.initials: D
authors.lastname: Nandi
authors.forename: Yang-Ming
authors.initials: YM
authors.lastname: Jhou
authors.forename: Jhen-Yi
authors.initials: JY
authors.lastname: Lee
authors.forename: Bing-Chiuan
authors.initials: BC
authors.lastname: Kuo
authors.forename: Chien-Yu
authors.initials: CY
authors.lastname: Liu
authors.forename: Pei-Wen
authors.initials: PW
authors.lastname: Huang
authors.forename: Hon Man
authors.initials: HM
authors.lastname: Lee
mesh_terms: D002384:Catalysis; D003653:Decarboxylation; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D006841:Hydrocarbons, Aromatic; D010165:Palladium