title: Porcine bladder extracellular matrix for closure of a large defect in a burn contracture release.
abstract: Porcine bladder extracellular matrix (PBEM) is an innovative wound healing alternative to traditional wound closure and reconstruction. By stimulating blood vessel formation and chemotaxis of progenitor cells to the site of injury, it promotes a unique healing environment favouring regeneration of native tissue over scar formation. This is the first clinical report describing the novel use of PBEM scaffold material to close a large defect resulting from a burn contracture release. The benefits of this method are the improved functional and cosmetic result. PBEM-moderated tissue regeneration may serve a valuable role in burn reconstruction.
authors.forename: K B
authors.initials: KB
authors.lastname: Mitchell
authors.forename: J J
authors.initials: JJ
authors.lastname: Gallagher
mesh_terms: D000818:Animals; D002056:Burns / Q000601:surgery*; D003286:Contracture / Q000601:surgery*; D005109:Extracellular Matrix / Q000637:transplantation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019838:Neck Injuries / Q000601:surgery*; D013552:Swine; D001743:Urinary Bladder / Q000166:cytology*; D014945:Wound Healing / Q000502:physiology*