title: Circumscribed palmar hypokeratosis: Successful treatment with fluorouracil cream.
abstract: BACKGROUND
  The pathogenesis of circumscribed palmar hypokeratosis (CPH) is still controversial, and to date there is no treatment of choice.
  
  
  METHODS
  We report on a patient with CPH responding to treatment with fluorouracil cream.
  
  
  RESULTS
  The clinical course and histopathological features in our observation point towards the possibility of an underlying squamous cell carcinoma in situ presenting as CPH.
  
  
  CONCLUSIONS
  We suggest that fluorouracil cream treatment should be considered as a therapeutic option in cases of CPH.
authors.affiliation: Dermatohistological Laboratory and Private Practice, Postfach 4145, 90021 Nuernberg, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Wilk
authors.forename: Bettina G
authors.initials: BG
authors.lastname: Zelger
authors.forename: Bernhard
authors.initials: B
authors.lastname: Zelger