title: Miscellaneous central nervous system intoxicants.
abstract: The topic of central nervous system intoxicants encompasses a multitude of agents. This article focuses on three classes of therapeutic drugs, with specific examples in which overdoses require admission to the intensive care unit. Included are some of the newer antidepressants, the atypical neuroleptic agents, and selected anticonvulsant drugs. The importance of understanding pertinent physiology and applicable supportive care is emphasized.
authors.affiliation: Department of Emergency Medicine, Detroit Receiving Hospital, Children's Hospital of Michigan Regional Poison Control Center, Wayne State University, Hutzel Building, 4707 Street Antoine, Suite 302, Detroit, MI 48201, USA. mhedge@dmc.org
authors.forename: Matthew W
authors.initials: MW
authors.lastname: Hedge
mesh_terms: D058109:Airway Management; D000927:Anticonvulsants / Q000378:metabolism / Q000506:poisoning*; D018687:Antidepressive Agents, Second-Generation / Q000378:metabolism / Q000506:poisoning*; D014150:Antipsychotic Agents / Q000378:metabolism / Q000506:poisoning*; D062787:Drug Overdose / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D012640:Seizures / Q000139:chemically induced / Q000188:drug therapy
chemical_list: D000927:Anticonvulsants; D018687:Antidepressive Agents, Second-Generation; D014150:Antipsychotic Agents