title: [Analysis on changes of sclerotin volume during the self-repairing process of bone defect].
abstract: Bone maintenance theory considers that the external load is the direct stimulating source of the bone remodeling. In this article, the method of experimental observation of self-repairing process of the bone defect and related results are introduced. Firstly, a hole was drilled in the rabbit thighbone so that the continuity of the bone was changed. Then bone defect model was established, and the thighbone data were obtained by using CT scanning, and the self-repairing process of bone defects caused by growth factor were observed and analyzed by MIMICS software. Finally, the relationship between volume changes of sclerotin was established, and scientific bases were provided for introducing the bionic topology optimization method to the remodeling process. The experimental results showed that the self-repairing of the each layer sclerotin of the young rabbits was faster than that of the adult ones under the same condition. In addition, the volume always changes contrarily between the spongy bone and enamel bone during the self-repairing process of bone defect.
authors.affiliation: School of Mechanical Engineering, Xinjiang University, Urumqi 830047, China.
authors.forename: Mamut
authors.initials: M
authors.lastname: Mamatjan
authors.forename: Geni
authors.initials: G
authors.lastname: Mamtimin
authors.forename: Yusup
authors.initials: Y
authors.lastname: Nijat
authors.forename: Rui
authors.initials: R
authors.lastname: Zhang
authors.forename: Ablat
authors.initials: A
authors.lastname: Arxidin
authors.forename: Yusup
authors.initials: Y
authors.lastname: Muhtar
authors.forename: Mahmut
authors.initials: M
authors.lastname: Akrem
authors.forename: Matruzi
authors.initials: M
authors.lastname: Jurat
authors.forename: Turdi
authors.initials: T
authors.lastname: Mamattursun
mesh_terms: D000818:Animals; D001861:Bone Regeneration / Q000502:physiology*; D005260:Female; D005264:Femoral Fractures / Q000503:physiopathology*; D005269:Femur / Q000293:injuries*; D017102:Fracture Healing / Q000502:physiology*; D008297:Male; D010012:Osteogenesis / Q000502:physiology; D011817:Rabbits