title: Resistant invasive aspergillosis in an autosomal recessive chronic granulomatous disease.
abstract: Chronic granulomatous disease (CGD) is an inherited immunodeficiency characterized by severe bacterial and fungal infections. Invasive aspergillosis and other rare mold diseases are the leading causes of mortality. We report one case of CGD revealed by retropharyngeal abscess. On evolution, the patient developed an invasive aspergillosis resistant to treatment.
authors.affiliation: Department of Pediatrics, CHU Hedi Chaker, Sfax, Tunisia. sfaihilamia@yahoo.fr
authors.forename: Lamia
authors.initials: L
authors.lastname: Sfaihi
authors.forename: Ines
authors.initials: I
authors.lastname: Maaloul
authors.forename: Hela
authors.initials: H
authors.lastname: Fourati
authors.forename: Marie José
authors.initials: MJ
authors.lastname: Stasia
authors.forename: Zeineb
authors.initials: Z
authors.lastname: Mnif
authors.forename: Mongia
authors.initials: M
authors.lastname: Hachicha
mesh_terms: D017668:Age of Onset; D000935:Antifungal Agents / Q000627:therapeutic use; D002675:Child, Preschool; D017809:Fatal Outcome; D006105:Granulomatous Disease, Chronic / Q000150:complications* / Q000235:genetics / Q000382:microbiology; D006801:Humans; D007223:Infant; D055744:Invasive Pulmonary Aspergillosis / Q000150:complications / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology*; D008297:Male; D019255:NADPH Oxidases / Q000172:deficiency* / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D000935:Antifungal Agents; D019255:NADPH Oxidases; C086986:CYBA protein, human