title: [Association of polymorphisms in glutathione-S-transferase and DNA repair genes with ovarian cancer risk in the Russian population].
abstract: Polymorphism ofglutathione-S-transferase (GSTA1, GSTM1, GSTM3, GSTP1, and GSTT1) and DNA repair (ERCC1, ERCC2, and XRCC1) genes in samples of ovarian cancer patients and healthy women of the Russian ethnic group was studied. A trend in the allele frequency variation of ERCC2 gene single nucleotide polymorphism (rs13181, A > C) was revealed. The A allele frequency was higher in the sample of patients (60,6% versus 52,9%, P = 0.058).
authors.forename: D V
authors.initials: DV
authors.lastname: Khokhrin
authors.forename: A V
authors.initials: AV
authors.lastname: Khrunin
authors.forename: A A
authors.initials: AA
authors.lastname: Moiseev
authors.forename: V A
authors.initials: VA
authors.lastname: Gorbunov
authors.forename: S A
authors.initials: SA
authors.lastname: Limborskaia
mesh_terms: D045643:DNA Repair Enzymes / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease; D005838:Genotype; D005982:Glutathione Transferase / Q000235:genetics; D006801:Humans; D010051:Ovarian Neoplasms / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide; D012307:Risk Factors; D012426:Russia; D051759:Xeroderma Pigmentosum Group D Protein / Q000235:genetics*
chemical_list: D005982:Glutathione Transferase; D051759:Xeroderma Pigmentosum Group D Protein; C497292:ERCC2 protein, human; D045643:DNA Repair Enzymes