title: [Latent chronic kidney disease in the material of the Department of Vascular Surgery, Pomeranian Medical University in Szczecin. An important clinical problem].
abstract: BACKGROUND
  The percentage of patients with diagnosed chronic renal failure is many times smaller than the percentage of the latent disease. The rate of cardiovascular complications in latent kidney disease is significantly higher. The aim of this work was to determine the percentage of patients with renal failure among patients with peripheral atherosclerosis treated at our Department and to study rate (GFR) below the influence of reduced glomerular filtration rate (GFR) below 60 mL/min/1.73 m2 on the risk of early complications after vascular surgery.
  
  
  METHODS
  A retrospective analysis of 1096 patients was done. 652 patients were operated, 321 underwent endovascular procedures, including angiography, antiglobulin test (PTA), and fibrinolysis, and 123 were conservatively treated. There were no significant differences between these groups as regards biochemical parameters prior to treatment.
  
  
  RESULTS
  Approximately 2% of patients presented with chronic renal failure at admission. However, GFR in more than 30% (370) of them was lower than 60 mL/min/1.73 m2. The incidence of myocardial infarction and pneumonia was more than three-fold greater in patients with reduced GFR (1.89 vs. 0.55, p = 0.042; 4.59 vs. 1.38, p = 0.0017, respectively). The incidence of gastrointestinal bleeding increased more than 18 times (3.78 vs. 0.28, p = 0.00002) and the incidence of stroke increased six times (2.43 vs. 0.41, p = 0.0032) in these patients.
  
  
  CONCLUSIONS
  Latent renal failure is present in more than one-third of patients treated for peripheral atherosclerosis. GFR below 60 mL/min/1.73 m2 is associated with a higher risk of cardiovascular complications and postoperative gastrointestinal bleeding. Glomerular filtration rate should be routinely calculated at admission to hospital.
authors.affiliation: Klinika Chirurgii Naczyniowej, Ogólnej i Angiologii Pomorskiego Uniwersytetu Medycznego w Szczecinie al. Powstańców Wlkp. 72, 70-111 Szczecin.
authors.forename: Arkadiusz
authors.initials: A
authors.lastname: Kazimierczak
authors.forename: Marcin
authors.initials: M
authors.lastname: Sledź
authors.forename: Renata
authors.initials: R
authors.lastname: Guzicka-Kazimierczak
authors.forename: Piotr
authors.initials: P
authors.lastname: Gutowski
authors.forename: Miłosław
authors.initials: M
authors.lastname: Cnotliwy
mesh_terms: D050197:Atherosclerosis / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery*; D015897:Comorbidity; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000453:epidemiology; D005919:Glomerular Filtration Rate; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D011044:Poland; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D020521:Stroke / Q000453:epidemiology; D013503:Surgery Department, Hospital / Q000706:statistics & numerical data; D014656:Vascular Surgical Procedures / Q000706:statistics & numerical data