title: Decreasing activity and altered protein processing of human iduronate-2-sulfatase mutations demonstrated by expression in COS7 cells.
authors.affiliation: Laboratory of Biochemistry, Chulabhorn Research Institute, Bangkok, 10210, Thailand.
authors.forename: Ratana
authors.initials: R
authors.lastname: Charoenwattanasatien
authors.forename: James R Ketudat
authors.initials: JR
authors.lastname: Cairns
authors.forename: Siriporn
authors.initials: S
authors.lastname: Keeratichamroen
authors.forename: Phannee
authors.initials: P
authors.lastname: Sawangareetrakul
authors.forename: Pranoot
authors.initials: P
authors.lastname: Tanpaiboon
authors.forename: Duangrurdee
authors.initials: D
authors.lastname: Wattanasirichaigoon
authors.forename: Suthipong
authors.initials: S
authors.lastname: Pangkanon
authors.forename: Jisnuson
authors.initials: J
authors.lastname: Svasti
authors.forename: Voraratt
authors.initials: V
authors.lastname: Champattanachai
mesh_terms: D000818:Animals; D019556:COS Cells; D020134:Catalytic Domain; D002522:Chlorocebus aethiops; D004789:Enzyme Activation; D015971:Gene Expression Regulation, Enzymologic; D006023:Glycoproteins / Q000235:genetics* / Q000378:metabolism; D006031:Glycosylation; D006801:Humans; D007962:Leukocytes / Q000201:enzymology; D016532:Mucopolysaccharidosis II / Q000235:genetics* / Q000473:pathology; D009154:Mutation; D010957:Plasmids / Q000235:genetics / Q000378:metabolism; D011487:Protein Conformation; D017510:Protein Folding; D012720:Severity of Illness Index; D014162:Transfection
chemical_list: D006023:Glycoproteins; C018322:IDS protein, human