title: The embryonic septum and ventral pallium, new sources of olfactory cortex cells.
abstract: The mammalian olfactory cortex is a complex structure located along the rostro-caudal extension of the ventrolateral prosencephalon, which is divided into several anatomically and functionally distinct areas: the anterior olfactory nucleus, piriform cortex, olfactory tubercle, amygdaloid olfactory nuclei, and the more caudal entorhinal cortex. Multiple forebrain progenitor domains contribute to the cellular diversity of the olfactory cortex, which is invaded simultaneously by cells originating in distinct germinal areas in the dorsal and ventral forebrain. Using a combination of dye labeling techniques, we identified two novel areas that contribute cells to the developing olfactory cortices, the septum and the ventral pallium, from which cells migrate along a radial and then a tangential path. We characterized these cell populations by comparing their expression of calretinin, calbindin, reelin and Tbr1 with that of other olfactory cell populations.
authors.affiliation: University of Chile, Las Encinas, Santiago, Chile.
authors.forename: María Laura
authors.initials: ML
authors.lastname: Ceci
authors.forename: María
authors.initials: M
authors.lastname: Pedraza
authors.forename: Juan A
authors.initials: JA
authors.lastname: de Carlos
mesh_terms: D000818:Animals; D064032:Calbindin 2; D064026:Calbindins; D015816:Cell Adhesion Molecules, Neuronal / Q000378:metabolism; D002465:Cell Movement; D004396:Coloring Agents / Q000494:pharmacology; D016326:Extracellular Matrix Proteins / Q000378:metabolism; D005260:Female; D051379:Mice; D008810:Mice, Inbred C57BL; D009419:Nerve Tissue Proteins / Q000378:metabolism; D009434:Neural Pathways / Q000166:cytology / Q000502:physiology*; D009474:Neurons / Q000378:metabolism; D009833:Olfactory Pathways / Q000166:cytology*; D011247:Pregnancy; D011270:Pregnancy, Animal; D016548:Prosencephalon / Q000196:embryology* / Q000502:physiology*; D000091042:Reelin Protein; D064030:S100 Calcium Binding Protein G / Q000378:metabolism; D012697:Serine Endopeptidases / Q000378:metabolism; D013997:Time Factors
chemical_list: C576511:Calb2 protein, mouse; D064032:Calbindin 2; D064026:Calbindins; D015816:Cell Adhesion Molecules, Neuronal; D004396:Coloring Agents; D016326:Extracellular Matrix Proteins; D009419:Nerve Tissue Proteins; D000091042:Reelin Protein; D064030:S100 Calcium Binding Protein G; C000717128:Reln protein, mouse; D012697:Serine Endopeptidases