title: TNM stages and prognostic features of colorectal mucinous adenocarcinomas: a meta analysis.
abstract: OBJECTIVE
  The significance of the mucinous adenocarcinoma in TNM staging and prognosis for colorectal tumor patients is still controversial. The aim was to provide a meta-analysis for TNM staging and prognostic features of colorectal tumors.
  
  
  METHODS
  30 individual case-control studies were finally included into this meta-analysis, involving a total of 444,489 cancer cases and 45,050 mucinous adenocarcinomas, of relations with TNM staging and prognostic features.
  
  
  RESULTS
  Compared to non-mucinous adenocarcinoma patients, the TNM IV stage accounted for a larger percentage of mucinous adenocarcinomas (OR=1.48, 95%CI 1.28-1.71, POR<0.001) and the prognosis was significantly poor (HR=1.06, 95%CI 1.04-1.08, P<0.001). After heterogeneity testing, the results was similar to the holistic approach outcome (HR=1.48, 95%CI 1.35-1.62, P<0.001).
  
  
  CONCLUSIONS
  Compared to patients with non-mucinous adenocarcinomas, mucinous adenocarcinoma patients with later TNM staging make up a big percentage, and mucinous adenocarcinoma is an independent risk factor for poor prognosis.
authors.affiliation: Department of Emergency, Jiangjin Central Hospital, Chongqing, China.
authors.forename: Jing-Xiang
authors.initials: JX
authors.lastname: Chen
authors.forename: Xu-Dong
authors.initials: XD
authors.lastname: Tang
authors.forename: De-Bing
authors.initials: DB
authors.lastname: Xiang
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Dong
authors.forename: Fang-Yi
authors.initials: FY
authors.lastname: Peng
authors.forename: Gui-Yin
authors.initials: GY
authors.lastname: Sun
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000473:pathology*; D016022:Case-Control Studies; D015179:Colorectal Neoplasms / Q000473:pathology*; D004311:Double-Blind Method; D006801:Humans; D009367:Neoplasm Staging / Q000379:methods; D011379:Prognosis; D012307:Risk Factors