title: The effect of daily fluoride mouth rinsing on enamel erosive/abrasive wear in situ.
abstract: It is not known whether application of fluoride agents on enamel results in lasting resistance to erosive/abrasive wear. We investigated if one daily mouth rinse with sodium fluoride (NaF), stannous fluoride (SnF(2)) or titanium tetrafluoride (TiF(4)) solutions protected enamel against erosive/abrasive wear in situ (a paired, randomised and blind study). Sixteen molars were cut into 4 specimens, each with one amalgam filling (measurement reference surface). Two teeth (2 × 4 specimens) were mounted bilaterally (buccal aspects) on acrylic mandibular appliances and worn for 9 days by 8 volunteers. Every morning, the specimens were brushed manually with water (30 s) extra-orally. Then fluoride solutions (0.4% SnF(2) pH 2.5; 0.15% TiF(4) pH 2.1; 0.2% NaF pH 6.5, all 0.05 M F) were applied (2 min). Three of the specimens from each tooth got different treatment, and the fourth served as control. At midday, the specimens were etched for 2 min in 300 ml fresh 0.01 M hydrochloric acid and rinsed in tap water. This etch procedure was repeated in the afternoon. Topographic measurements were performed by a white-light interferometer. Mean surface loss (±SD) for 16 teeth after 9 days was: SnF(2) 1.8 ± 1.9 µm, TiF(4) 3.1 ± 4.8 µm, NaF 26.3 ± 4.7 µm, control 32.3 ± 4.4 µm. Daily rinse with SnF(2), TiF(4) and NaF resulted in 94, 90 and 18% reduction in enamel erosive/abrasive wear, respectively, compared with control (p < 0.05). The superior protective effect of daily rinse with either stannous or titanium tetrafluoride solutions on erosive/abrasive enamel wear is promising.
authors.affiliation: Faculty of Dentistry, University of Oslo, Oslo, Norway. k.r.stenhagen@odont.uio.no
authors.forename: K R
authors.initials: KR
authors.lastname: Stenhagen
authors.forename: L H
authors.initials: LH
authors.lastname: Hove
authors.forename: B
authors.initials: B
authors.lastname: Holme
authors.forename: A B
authors.initials: AB
authors.lastname: Tveit
mesh_terms: D000328:Adult; D002327:Cariostatic Agents / Q000627:therapeutic use*; D003743:Dental Enamel / Q000187:drug effects*; D005260:Female; D005459:Fluorides / Q000627:therapeutic use*; D006801:Humans; D006851:Hydrochloric Acid / Q000494:pharmacology; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007368:Interferometry / Q000295:instrumentation / Q000379:methods; D008297:Male; D009067:Mouthwashes / Q000627:therapeutic use*; D016037:Single-Blind Method; D012969:Sodium Fluoride / Q000627:therapeutic use; D014002:Tin Fluorides / Q000627:therapeutic use; D014025:Titanium / Q000627:therapeutic use; D014072:Tooth Abrasion / Q000517:prevention & control*; D014077:Tooth Erosion / Q000517:prevention & control*; D014099:Toothbrushing / Q000295:instrumentation; D014100:Toothpastes / Q000627:therapeutic use; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D002327:Cariostatic Agents; D009067:Mouthwashes; D014002:Tin Fluorides; D014100:Toothpastes; D012969:Sodium Fluoride; D014025:Titanium; D005459:Fluorides; D006851:Hydrochloric Acid; C032240:titanium tetrafluoride