title: Glycemic variability and glycemic control in the acutely ill cardiac patient.
abstract: The mechanisms for hyperglycemia-mediated harm in the hospitalized cardiac patient are poorly understood. Potential obstacles in the inpatient management of hyperglycemia in cardiac patients include rapidly changing clinical status, frequent procedures and interruptions in carbohydrate exposure, and short hospital length of stay. A patient's preadmission regimen is rarely suitable for inpatient glycemic control. Instead, an approach to a flexible, physiologic insulin regimen is described, which is intended to minimize glycemic excursions. When diabetes or hyperglycemia is addressed early and consistently, the hospital stay can serve as a potential window of opportunity for reinforcing self-care behaviors that reduce long-term complications.
authors.affiliation: Department of Internal Medicine, The Ohio State University, 2050 Kenny Road, Columbus, OH 43221-3502, USA.
authors.forename: Jared
authors.initials: J
authors.lastname: Moore
authors.forename: Kathleen
authors.initials: K
authors.lastname: Dungan
mesh_terms: D000208:Acute Disease; D001786:Blood Glucose / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000378:metabolism* / Q000473:pathology; D003920:Diabetes Mellitus / Q000378:metabolism* / Q000473:pathology / Q000517:prevention & control; D052216:Glucagon-Like Peptide 1; D006801:Humans; D006943:Hyperglycemia / Q000378:metabolism* / Q000473:pathology / Q000517:prevention & control; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use; D012306:Risk
chemical_list: D001786:Blood Glucose; D007328:Insulin; D052216:Glucagon-Like Peptide 1