title: A portable and power-free microfluidic device for rapid and sensitive lead (Pb2+) detection.
abstract: A portable and power-free microfluidic device was designed for rapid and sensitive detection of lead (Pb(2+)). 11-mercaptoundecanoic acid (MUA)-functionalized gold nanoparticles (MUA-AuNPs) aggregated in the presence of Pb(2+) for the chelation mechanism. When we performed this analysis on a polydimethylsiloxane (PDMS) microfluidic chip, the aggregations deposited onto the surface of chip and formed dark lines along the laminar flows in the zigzag microchannels. This visual result can be observed by the naked eye through a microscope or just a drop of water as a magnifier. Ten μM Pb(2+) was successfully detected.
authors.affiliation: Laboratory of Advanced Materials, Fudan University, 2205 Songhu Road, Shanghai 200438, China. 09213010009@fudan.edu.cn
authors.forename: Chunhui
authors.initials: C
authors.lastname: Fan
authors.forename: Shijiang
authors.initials: S
authors.lastname: He
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
authors.forename: Lianhui
authors.initials: L
authors.lastname: Wang
authors.forename: Shiping
authors.initials: S
authors.lastname: Song
mesh_terms: D004129:Dimethylpolysiloxanes / Q000737:chemistry; D005227:Fatty Acids / Q000737:chemistry; D006046:Gold / Q000737:chemistry; D007477:Ions / Q000737:chemistry; D007854:Lead / Q000032:analysis*; D053768:Metal Nanoparticles / Q000737:chemistry; D046210:Microfluidic Analytical Techniques; D013438:Sulfhydryl Compounds / Q000737:chemistry
chemical_list: C505222:11-mercaptoundecanoic acid; D004129:Dimethylpolysiloxanes; D005227:Fatty Acids; D007477:Ions; D013438:Sulfhydryl Compounds; D007854:Lead; C013830:baysilon; D006046:Gold