title: The diagnostic value of narrow-band imaging for the detection of nasopharyngeal carcinoma.
abstract: OBJECTIVE
  To evaluate the diagnostic value of narrow-band imaging (NBI) for the detection of nasopharyngeal carcinoma (NPC).
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  Tertiary medical center.
  
  
  METHODS
  Between December 2009 and June 2010, a total of 1,854 patients were examined by means of an electronic nasopharyngolaryngoscope equipped with conventional white light (WL) and an NBI system. The sensitivity, specificity and positive/negative predictive values for detecting NPC were calculated and compared.
  
  
  RESULTS
  Of these patients, 62 cases (3.34%) were pathologically confirmed as NPC. The sensitivity, specificity, positive predictive value and negative predictive value for detecting NPC significantly increased from 90.3, 75.4, 11.3 and 99.6% with WL up to 100, 99.2, 81.6 and 100% with NBI, respectively.
  
  
  CONCLUSIONS
  Our findings suggested that NBI endoscopy might serve as an ideal tool in the detection of NPC.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Sun Yat-sen Memorial Hospital, Guangzhou, China.
authors.forename: Haidi
authors.initials: H
authors.lastname: Yang
authors.forename: Yiqing
authors.initials: Y
authors.lastname: Zheng
authors.forename: Qiujian
authors.initials: Q
authors.lastname: Chen
authors.forename: Hao
authors.initials: H
authors.lastname: Xiong
authors.forename: Bin
authors.initials: B
authors.lastname: Chen
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Zhang
authors.forename: Xiaoming
authors.initials: X
authors.lastname: Huang
authors.forename: Jieren
authors.initials: J
authors.lastname: Peng
mesh_terms: D000328:Adult; D002277:Carcinoma; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000628:therapy; D002681:China; D004724:Endoscopy; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008297:Male; D008875:Middle Aged; D062048:Narrow Band Imaging; D000077274:Nasopharyngeal Carcinoma; D009303:Nasopharyngeal Neoplasms / Q000473:pathology* / Q000628:therapy; D011237:Predictive Value of Tests; D011446:Prospective Studies