title: Total synthesis of cyclocitropside A and its conversion to cyclocitropsides B and C via asparagine deamidation.
abstract: The total syntheses of three closely related cyclic peptide natural products, cyclocitropsides A-C, are described. Cyclocitropside A could be readily converted into cyclocitropsides B and C through an asparagine deamidation pathway, indicating that this is a plausible biosynthetic route to these compounds.
authors.affiliation: School of Chemistry, The University of Sydney, NSW 2006, Australia.
authors.forename: Robert E
authors.initials: RE
authors.lastname: Thompson
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Payne
authors.forename: Katrina A
authors.initials: KA
authors.lastname: Jolliffe
mesh_terms: D001216:Asparagine / Q000737:chemistry; D003641:Deamination; D015394:Molecular Structure; D010456:Peptides, Cyclic / Q000138:chemical synthesis*
chemical_list: D010456:Peptides, Cyclic; C579587:cyclocitropside A; C579590:cyclocitropside B; C579589:cyclocitropside C; D001216:Asparagine