title: The metabolic syndrome of fructose-fed rats: effects of long-chain polyunsaturated ω3 and ω6 fatty acids. V. Post-mortem findings.
abstract: The present study deals with the possible effects of dietary ω3 and ω6 fatty             acids upon the metabolic syndrome found in rats exposed for 8 weeks to a diet             containing 64% (w/w) D-fructose instead of starch. Fructose-fed rats were found             to display a modest increase in plasma albumin and protein concentration and more             pronounced increases in plasma urea, creatinine, phospholipids, triglycerides             and cholesterol concentrations, glycated hemoglobin concentration and liver contents             of cholesterol, triglycerides and phospholipids. The plasma concentrations of             HDL-cholesterol, calcium and iron were decreased, however, in the fructose-fed             rats. In general, the partial substitution of sunflower oil by either safflower             oil or salmon oil opposed the metabolic perturbations otherwise associated with             the fructose-induced metabolic syndrome in the fructose-fed rats, with salmon             oil demonstrating particular efficacy. Consideration is given to the possible             biological determinants of these perturbations and their attenuation in rats exposed             to safflower or salmon oil.
authors.affiliation: Department of Biology, Es-Sénia University, Es-Sénia 31000, Oran,                     Algeria.
authors.forename: Zoheir
authors.initials: Z
authors.lastname: Mellouk
authors.forename: Karim
authors.initials: K
authors.lastname: Louchami
authors.forename: Emeline
authors.initials: E
authors.lastname: Hupkens
authors.forename: Abdullah
authors.initials: A
authors.lastname: Sener
authors.forename: Dalila
authors.initials: D
authors.lastname: Ait Yahia
authors.forename: Willy J
authors.initials: WJ
authors.lastname: Malaisse
mesh_terms: D000818:Animals; D002118:Calcium / Q000097:blood; D002784:Cholesterol / Q000097:blood; D019587:Dietary Supplements; D015525:Fatty Acids, Omega-3 / Q000494:pharmacology*; D043371:Fatty Acids, Omega-6 / Q000494:pharmacology*; D005260:Female; D005395:Fish Oils / Q000494:pharmacology; D005632:Fructose / Q000494:pharmacology*; D007501:Iron / Q000097:blood; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D024821:Metabolic Syndrome / Q000209:etiology / Q000378:metabolism* / Q000473:pathology; D010743:Phospholipids / Q000097:blood; D010938:Plant Oils / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D012450:Safflower Oil / Q000494:pharmacology; D000074242:Sunflower Oil; D014280:Triglycerides / Q000097:blood
chemical_list: D015525:Fatty Acids, Omega-3; D043371:Fatty Acids, Omega-6; D005395:Fish Oils; D010743:Phospholipids; D010938:Plant Oils; D000074242:Sunflower Oil; D014280:Triglycerides; D005632:Fructose; C030341:salmon oil; D012450:Safflower Oil; D002784:Cholesterol; D007501:Iron; D002118:Calcium