title: Neuroimaging characteristics and growth pattern on magnetic resonance imaging in a 52-year-old man presenting with pituicytoma: a case report.
abstract: BACKGROUND
  Pituicytoma is a rare neoplasm of the neurohypophysis. To the best of our knowledge there have been no reports of pituicytoma in which long-term magnetic resonance imaging observation was performed. We calculated the doubling time of the tumor volume and described the growth pattern of a pituicytoma.
  
  
  METHODS
  A 52-year-old Japanese man with a history of decreased libido was found to have a sellar and suprasellar mass. He underwent transsphenoidal surgery, but only a small specimen was obtained because of intraoperative bleeding. The tentative histological diagnosis was schwannoma. He noticed bitemporal hemianopsia 7 years later. A follow-up magnetic resonance imaging disclosed a tumor volume doubling time of 3830 days. Transcranial gross-total tumor resection was performed. The lesion consisted of elongated and plump tumor cells that were arranged in a fascicular or storiform pattern and were positive for S-100 protein and focally positive for glial fibrillary acidic protein. The final histological diagnosis was pituicytoma.
  
  
  CONCLUSIONS
  Pituicytoma is a slow-growing tumor, but the growth rate may change during follow-up.
authors.affiliation: Department of Neurosurgery, St, Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa, 216-8511, Japan. kosugeyasushi@marianna-u.ac.jp.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Kosuge
authors.forename: Jun
authors.initials: J
authors.lastname: Hiramoto
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Morishima
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Takuo
authors.initials: T
authors.lastname: Hashimoto