title: Intermolecular G-quadruplex-based universal quencher free molecular beacon.
abstract: A simple and universal quencher-free molecular beacon (MB) with low background fluorescence is developed based on an intermolecular G-quadruplex signaling probe. Unlike previous fluorescent MB strategies, it can function without any fluorophore and quencher modifications on its hairpin sequence.
authors.affiliation: State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, PR China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhou
authors.forename: Su-Jin
authors.initials: SJ
authors.lastname: Xie
authors.forename: Ji-Shan
authors.initials: JS
authors.lastname: Li
authors.forename: Zai-Sheng
authors.initials: ZS
authors.lastname: Wu
authors.forename: Guo-Li
authors.initials: GL
authors.lastname: Shen
mesh_terms: D005453:Fluorescence; D054856:G-Quadruplexes; D015341:Nucleic Acid Probes / Q000737:chemistry*
chemical_list: D015341:Nucleic Acid Probes