title: Two cases of urinary tract infection caused by Shiga toxin-producing Escherichia coli O157:H7 strains.
abstract: STEC strains can infect extra-intestinal sites such as the human urinary tract and sometimes cause severe complications. We report two cases of urinary tract infection caused by STEC in two elderly women with comorbidities. Although both strains belonged to the O157:H7 serotype and carried genes associated with severe illness, none of the patients developed hemolytic uremic syndrome (HUS). These findings provide additional evidence for the presence of these agents in our country and in the region, and highlight the need to maintain an active surveillance system of HUS cases, placing special emphasis on the study of other sites of infection in patients with non-diarrheal HUS.
authors.affiliation: Departamento de Bacteriología y Virología, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.
authors.forename: María Del P
authors.initials: Mdel P
authors.lastname: Gadea
authors.forename: Natalia
authors.initials: N
authors.lastname: Deza
authors.forename: María I
authors.initials: MI
authors.lastname: Mota
authors.forename: Carolina
authors.initials: C
authors.lastname: Carbonari
authors.forename: Mitila
authors.initials: M
authors.lastname: Robatto
authors.forename: Beatriz
authors.initials: B
authors.lastname: D'Astek
authors.forename: Victoria
authors.initials: V
authors.lastname: Balseiro
authors.forename: Cristina
authors.initials: C
authors.lastname: Bazet
authors.forename: Eduardo
authors.initials: E
authors.lastname: Rügnitz
authors.forename: Valérie
authors.initials: V
authors.lastname: Livrelli
authors.forename: Felipe
authors.initials: F
authors.lastname: Schelotto
authors.forename: Marta
authors.initials: M
authors.lastname: Rivas
authors.forename: Gustavo
authors.initials: G
authors.lastname: Varela
mesh_terms: D018829:Adhesins, Bacterial / Q000235:genetics; D000368:Aged; D000369:Aged, 80 and over; D001118:Argentina / Q000453:epidemiology; D015373:Bacterial Typing Techniques; D003556:Cystitis / Q000382:microbiology; D003967:Diarrhea / Q000150:complications; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology*; D019453:Escherichia coli O157 / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D029968:Escherichia coli Proteins / Q000235:genetics; D005260:Female; D036781:Fimbriae Proteins / Q000235:genetics; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications; D008826:Microbial Sensitivity Tests; D022603:Shiga Toxins / Q000235:genetics; D014552:Urinary Tract Infections / Q000150:complications / Q000382:microbiology*
chemical_list: D018829:Adhesins, Bacterial; D029968:Escherichia coli Proteins; D022603:Shiga Toxins; C063055:fimbrillin; C073819:eaeA protein, E coli; D036781:Fimbriae Proteins