title: Preparation and evaluation of biocomposites as wound dressing material.
abstract: Collagen was isolated from the chrome containing leather waste (CCLW) which is a major solid waste in leather industry. Composite films were made using sago starch (SG), soya protein (SY), and collagen (C) and were cross linked with glutaraldehyde (G).The films prepared were characterized for their physico chemical properties like tensile strength, infrared spectra, thermogravimetric analysis, surface morphology, and water absorption studies. Better mechanical properties and surface morphology were observed for SG-SY-G-C films compared to other films prepared using collagen. The composite films prepared were used as wound dressing material on the experimental wounds of rats and healing pattern was evaluated using planimetric, biochemical, and histopathological studies. These studies have revealed better wound healing capacity of SG-SY-G-C film and utilization of CCLW in the preparation of value added product like wound dressing material.
authors.affiliation: Bioproducts Lab, Central Leather Research Institute, Adyar, Chennai, 600020, India.
authors.forename: V
authors.initials: V
authors.lastname: Ramnath
authors.forename: S
authors.initials: S
authors.lastname: Sekar
authors.forename: S
authors.initials: S
authors.lastname: Sankar
authors.forename: C
authors.initials: C
authors.lastname: Sankaranarayanan
authors.forename: T P
authors.initials: TP
authors.lastname: Sastry
mesh_terms: D000818:Animals; D001458:Bandages; D001672:Biocompatible Materials / Q000737:chemistry*; D003094:Collagen / Q000737:chemistry; D008297:Male; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning / Q000379:methods; D015233:Models, Statistical; D051381:Rats; D017208:Rats, Wistar; D012639:Seeds; D013025:Glycine max; D013055:Spectrophotometry, Infrared / Q000379:methods; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods; D013499:Surface Properties; D013718:Tensile Strength; D013818:Thermogravimetry / Q000379:methods; D013997:Time Factors; D014945:Wound Healing
chemical_list: D001672:Biocompatible Materials; D003094:Collagen