title: OPA1 mutations induce mtDNA proliferation in leukocytes of patients with dominant optic atrophy.
authors.affiliation: Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: Kamil S
authors.initials: KS
authors.lastname: Sitarz
authors.forename: Gitte J
authors.initials: GJ
authors.lastname: Almind
authors.forename: Rita
authors.initials: R
authors.lastname: Horvath
authors.forename: Birgit
authors.initials: B
authors.lastname: Czermin
authors.forename: Karen
authors.initials: K
authors.lastname: Grønskov
authors.forename: Angela
authors.initials: A
authors.lastname: Pyle
authors.forename: Robert W
authors.initials: RW
authors.lastname: Taylor
authors.forename: Michael
authors.initials: M
authors.lastname: Larsen
authors.forename: Patrick F
authors.initials: PF
authors.lastname: Chinnery
authors.forename: Patrick
authors.initials: P
authors.lastname: Yu-Wai-Man
mesh_terms: D049109:Cell Proliferation; D015331:Cohort Studies; D056915:DNA Copy Number Variations / Q000235:genetics; D004272:DNA, Mitochondrial / Q000235:genetics*; D004739:England; D005260:Female; D020558:GTP Phosphohydrolases / Q000235:genetics*; D005858:Germany; D006801:Humans; D007962:Leukocytes / Q000378:metabolism*; D008297:Male; D009154:Mutation / Q000235:genetics*; D009426:Netherlands; D029241:Optic Atrophy, Autosomal Dominant / Q000235:genetics* / Q000473:pathology*; D014792:Visual Acuity / Q000235:genetics
chemical_list: D004272:DNA, Mitochondrial; D020558:GTP Phosphohydrolases; C415198:OPA1 protein, human