title: Multi-biomarker responses in fishes from two typical marine aquaculture regions of South China.
abstract: The impact of typical pollutants upon the fish-farming was assessed by use of a battery of biomarkers in two typical marine aquaculture regions in South China. Biotransformation parameters including 7-ethoxyresorufin-O-deethylase (EROD), aminopyrine N-demethylase (APND), erythromycin N-demethylase (ERND), glutathione-S-transferase (GST) and Malondialdehyde (MDA) were measured in five cultured fish species. Pollutants such as polycyclic aromatic hydrocarbon (PAHs), organochlorinated compounds (OCs), heavy metals and antibiotics (quinolones and sulfonamides) in sediments were characterized. Higher pollutant residue levels were observed in Dapeng Cove. EROD, APND and ERND activities were lower in fish from Dapeng Cove compared with fish from Hailing Island, while it is just on the contrary for GST and MDA. ERND, APND and GST showed sensitivity corresponding to different pollutants. Small fish species seemed to exhibit more sensitive to pollutants. The study further supports usefulness of multi-biomarker approach considering multiple species to define the effects of anthropogenic inputs in marine aquaculture systems.
authors.affiliation: Institute of Hydrobiology, Jinan University, Guangzhou 510632, China.
authors.forename: Xiuting
authors.initials: X
authors.lastname: He
authors.forename: Xiangping
authors.initials: X
authors.lastname: Nie
authors.forename: Yufeng
authors.initials: Y
authors.lastname: Yang
authors.forename: Xinyu
authors.initials: X
authors.lastname: Liu
authors.forename: Debo
authors.initials: D
authors.lastname: Pan
authors.forename: Zhang
authors.initials: Z
authors.lastname: Cheng
authors.forename: Ximei
authors.initials: X
authors.lastname: Liang
mesh_terms: D000633:Aminopyrine N-Demethylase / Q000378:metabolism; D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis / Q000633:toxicity; D017756:Aquaculture; D015415:Biomarkers / Q000378:metabolism; D002681:China; D019363:Cytochrome P-450 CYP1A1 / Q000378:metabolism; D051544:Cytochrome P-450 CYP3A / Q000378:metabolism; D004784:Environmental Monitoring; D005399:Fishes; D005982:Glutathione Transferase / Q000378:metabolism; D008315:Malondialdehyde; D019216:Metals, Heavy / Q000032:analysis / Q000633:toxicity; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis / Q000633:toxicity; D014874:Water Pollutants, Chemical; D014877:Water Pollution, Chemical / Q000706:statistics & numerical data
chemical_list: D000900:Anti-Bacterial Agents; D015415:Biomarkers; D019216:Metals, Heavy; D011084:Polycyclic Aromatic Hydrocarbons; D014874:Water Pollutants, Chemical; D008315:Malondialdehyde; D019363:Cytochrome P-450 CYP1A1; D051544:Cytochrome P-450 CYP3A; D000633:Aminopyrine N-Demethylase; D005982:Glutathione Transferase