title: Aeromonas aquariorum septicemia and enterocolitis in a cirrhotic patient.
abstract: Aeromonas aquariorum is a recently described Aeromonas species. We present a cirrhotic patient with septicemia and bloody diarrhea in whom A. aquariorum was isolated from the blood and stool. The species identification was based on sequence analysis of the partial rpoB and rpoD genes. The A. aquariorum isolates carried genes encoding hemolysin, aerolysin, and the cytotonic enterotoxin Alt. Significant A. aquariorum-induced cytotoxicity in intestinal epithelial cells was also demonstrated.
authors.affiliation: Department of Graduate Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
authors.forename: Chi-Jung
authors.initials: CJ
authors.lastname: Wu
authors.forename: Pei-Jane
authors.initials: PJ
authors.lastname: Tsai
authors.forename: Po-Lin
authors.initials: PL
authors.lastname: Chen
authors.forename: I-Chien
authors.initials: IC
authors.lastname: Wu
authors.forename: Yu-Tzu
authors.initials: YT
authors.lastname: Lin
authors.forename: Yi-Hsuan
authors.initials: YH
authors.lastname: Chen
authors.forename: Li-Rong
authors.initials: LR
authors.lastname: Wang
authors.forename: Wen-Chien
authors.initials: WC
authors.lastname: Ko
mesh_terms: D000333:Aeromonas / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D000369:Aged, 80 and over; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D012321:DNA-Directed RNA Polymerases / Q000235:genetics; D004760:Enterocolitis / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D004847:Epithelial Cells / Q000382:microbiology; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications*; D008969:Molecular Sequence Data; D018805:Sepsis / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D017422:Sequence Analysis, DNA; D012808:Sigma Factor / Q000235:genetics; D037521:Virulence Factors / Q000235:genetics
chemical_list: D004269:DNA, Bacterial; D012808:Sigma Factor; D037521:Virulence Factors; C081775:RNA polymerase sigma 70; D012321:DNA-Directed RNA Polymerases; C105078:RNA polymerase beta subunit