title: [The sub-microsecond pulser applied for electroporation effect].
abstract: A sub-microsecond pulse generation applied for electroporation effects of tumor cell is presented in this paper. The principle of the generator is that the expected pulse waveform is intercepted from the RC discharge curve by controlling the on-off states of two IGBT modules with a synchronous controller. Experimental tests indicate that the generator can produce adjustable pulse waveform parameters with 0.5-3.5kV amplitude, 300-800 ns pulse duration, 1-400Hz repetition frequency rate, and it is suitable for the study of the electroporation effect experiments.
authors.affiliation: Physical Electronics College, University of Electronics Science and Technology of China, Chengdu 610054, China.
authors.forename: Yafang
authors.initials: Y
authors.lastname: Tan
authors.forename: Hongchun
authors.initials: H
authors.lastname: Yang
authors.forename: Jianxing
authors.initials: J
authors.lastname: Wu
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Yang
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Gang
authors.initials: G
authors.lastname: Zeng
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D002462:Cell Membrane; D004560:Electricity; D018274:Electroporation / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D055616:Microtechnology / Q000295:instrumentation*; D009369:Neoplasms / Q000648:ultrastructure*