title: Endothelial chemokine receptors as facilitators of tumor cell extravasation?
abstract: Metastasis is a multistep process characterized by the ability of tumor cells to "communicate" and to interact with their microenvironment to establish tumors in distant organs. A significant proportion of the metastatic microenvironment consists of leukocytes, mostly of the innate immune system, contributing to tumor invasion and outgrowth.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Hoos
authors.forename: Monika J
authors.initials: MJ
authors.lastname: Wolf
authors.forename: Judith
authors.initials: J
authors.lastname: Bauer
authors.forename: Lubor
authors.initials: L
authors.lastname: Borsig
authors.forename: Mathias
authors.initials: M
authors.lastname: Heikenwalder
mesh_terms: D002450:Cell Communication / Q000502:physiology; D042783:Endothelial Cells / Q000473:pathology; D006801:Humans; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology*; D009360:Neoplastic Cells, Circulating / Q000473:pathology; D019707:Receptors, Chemokine / Q000378:metabolism*; D059016:Tumor Microenvironment / Q000502:physiology
chemical_list: D019707:Receptors, Chemokine