title: [Anesthetic management using muscle relaxant in a patient with amyotrophic lateral sclerosis].
abstract: A 31-year-old woman with amyotrophic lateral sclerosis (ALS) with respiratory muscle paralysis was scheduled for tracheotomy. After applying standard neuromuscular monitoring devices, general anesthesia was induced and maintained with propofol, remifentanil, rocuronium, and sevoflurane. Sugammadex is a potent agent for reversal of neuromuscular blockade by rocuronium. The patient emerged from general anesthesia smoothly using sugammadex; however, assisted respiration was continued for possible prolongation of the effect of muscle relaxant. The postoperative course was uneventful, and she was discharged without any discomfort.
authors.affiliation: Department of Anesthesiology, Tokushima University Hospital, Tokushima 770-8503.
authors.forename: Naohiro
authors.initials: N
authors.lastname: Ohshita
authors.forename: Yasuo M
authors.initials: YM
authors.lastname: Tsutsumi
authors.forename: Shuzo
authors.initials: S
authors.lastname: Oshita
authors.forename: Kaori
authors.initials: K
authors.lastname: Takata
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Tomiyama
authors.forename: Katsuya
authors.initials: K
authors.lastname: Tanaka
mesh_terms: D000328:Adult; D000690:Amyotrophic Lateral Sclerosis / Q000150:complications*; D000732:Androstanols; D000768:Anesthesia, General; D005260:Female; D006801:Humans; D003473:Neuromuscular Nondepolarizing Agents; D012133:Respiratory Paralysis / Q000209:etiology / Q000601:surgery; D000077123:Rocuronium; D000077122:Sugammadex; D014140:Tracheotomy; D047408:gamma-Cyclodextrins / Q000008:administration & dosage
chemical_list: D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D000077123:Rocuronium