title: [Eruptive melanocytic nevi during azathioprine therapy in myasthenia gravis].
abstract: While being treated with azathioprine and dexamethasone, a 21-year old man with myasthenia gravis suddenly developed rapidly progressing brown macules, predominantly on the trunk, palms and soles. We made a diagnosis of eruptive melanocytic nevi (EMN). This rare entity can appear after blistering skin diseases, in immunocompromised patients, and, in particular, during immunosuppressive therapy for autoimmune diseases. Since therapeutic regimens including azathioprine have been frequently reported in association with EMN, we recommended to our patient a treatment switch to mycophenolic acid to prevent the development of more nevi.
authors.affiliation: Hautklinik, Universitätsklinikum Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland.
authors.forename: S A
authors.initials: SA
authors.lastname: Braun
authors.forename: D
authors.initials: D
authors.lastname: Helbig
authors.forename: J
authors.initials: J
authors.lastname: Frank
authors.forename: S
authors.initials: S
authors.lastname: Hanneken
mesh_terms: D001379:Azathioprine / Q000009:adverse effects* / Q000627:therapeutic use; D003875:Drug Eruptions / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D009157:Myasthenia Gravis / Q000150:complications* / Q000188:drug therapy*; D009508:Nevus, Pigmented / Q000139:chemically induced* / Q000175:diagnosis / Q000517:prevention & control; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000175:diagnosis / Q000517:prevention & control; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D007166:Immunosuppressive Agents; D001379:Azathioprine