title: Direct lineage conversion: induced neuronal cells and induced neural stem cells.
abstract: Cellular reprogramming to neural cells is an area of ongoing study in developmental neuroscience, and recent research has generated remarkable achievements. Several studies have shown that the ectopic expression of specific neural transcription factors can convert terminally differentiated cells into neural cells. Here, we review the most recent progress in the field of induced neuronal (iN) cells and induced neural stem (iNS) cells and their potential clinical applications.
authors.affiliation: Institute of Zoology, State Key Laboratory of Reproductive Biology, Chinese Academy of Sciences, Beijing, China.
authors.forename: Zixiao
authors.initials: Z
authors.lastname: Shi
authors.forename: Jianwei
authors.initials: J
authors.lastname: Jiao
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D019070:Cell Lineage; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology / Q000378:metabolism; D058953:Neural Stem Cells / Q000166:cytology*; D009474:Neurons / Q000166:cytology* / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D014157:Transcription Factors