title: Sesquiterpene lactones from Inula helianthus-aquatica.
abstract: OBJECTIVE
  To investigate the sesquiterpene lactones of the aerial parts of Inula helianthus-aquatica.
  
  
  METHODS
  Compounds were isolated and purified by silica gel, Sephadex LH-20 and preparative HPLC. On the basis of physicochemical properties and spectroscopic data, their structures were identified.
  
  
  RESULTS
  Seven sesquiterpene lactones and four other compounds were obtained and identified as 2-desoxy-4-epi-pulchellin (1), 6-acetoxy-4-hydroxy-1, 10H-pseudoguaia-11 (13)-en-12,8-olide (2), 4-acetoxy-6-hydroxy-1, 10H-pseudoguaia-11(13)-en-12,8-olide (3), 8-epi-inuviscolide (4), 2,3,11,13-tetrahydroaromaticin (5), 11,13-dihydro-ergolide (6), 4-epipulchellin-2-O-acetate (7), 7-epiloliolide (8), loliolide (9), beta-sitosterol (10) and daucosterol (11).
  
  
  CONCLUSIONS
  All the compounds were isolated from this plant for the first time.
authors.affiliation: School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China.
authors.forename: Yaping
authors.initials: Y
authors.lastname: Hua
authors.forename: Jiangjiang
authors.initials: J
authors.lastname: Qin
authors.forename: Fei
authors.initials: F
authors.lastname: Zhang
authors.forename: Xiangrong
authors.initials: X
authors.lastname: Cheng
authors.forename: Huizi
authors.initials: H
authors.lastname: Jin
authors.forename: Weidong
authors.initials: W
authors.lastname: Zhang
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry; D038143:Inula / Q000737:chemistry*; D007783:Lactones / Q000032:analysis* / Q000737:chemistry* / Q000302:isolation & purification; D012717:Sesquiterpenes / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; D007783:Lactones; D012717:Sesquiterpenes