title: Desymmetrisation of meso-diols mediated by non-enzymatic acyl transfer catalysts.
abstract: Complementary to enzymatic methods, catalytic enantioselective desymmetrisation of meso-diols (EDMD) by small molecule catalysts has emerged as a powerful tool that provides highly enantioenriched materials of considerable value in organic synthesis. This review traces the evolution of easily accessible catalysts used in the EDMD and compares their performance with the existing enzymatic methods.
authors.affiliation: University of Geneva, Department of Organic Chemistry, Switzerland. enriquez_garcia_alvaro@lilly.com
authors.forename: Alvaro
authors.initials: A
authors.lastname: Enríquez-García
authors.forename: E Peter
authors.initials: EP
authors.lastname: Kündig
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry; D003959:Diamines / Q000737:chemistry; D006639:Histidine / Q000031:analogs & derivatives; D010720:Phosphines / Q000737:chemistry; D011725:Pyridines / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D056831:Coordination Complexes; D003959:Diamines; D010720:Phosphines; D011725:Pyridines; D006639:Histidine; C044646:phosphine; C023666:pyridine