title: [Epidemiology of occupational skin cancer due to UV-irradiation].
abstract: Skin cancer induced by occupational UV-irradiation is not an official occupational disease number in the appendix of the German ordinance on occupational diseases (Berufskrankheitenverordnung (BKV) but can be recognized as a "virtually" occupational disease according to § 9 (2) of the 7th book of the German Social Code (SGB VII). Epidemiological studies have demonstrated a positive, statistically significant and relevant association between occupational UV-irradiation and the risk of squamous cell carcinoma (SCC) and actinic keratoses (AK). Outdoor workers have on average a 100% higher risk to develop SCC compared to the general population. Therefore, the prerequisites for a new occupational disease are fulfilled and SCC and AK should be reported as an occupational disease if an additional 40% occupationally-related UV-irradiation is documented and the clinical criteria are typical for work- related skin cancer. Epidemiologic evidence also indicates a significant association between work-related UV-irradiation and basal cell carcinoma (BCC) risk: however the results are less consistent and the association is weaker than with SCC. There is an urgent need for further studies in outdoor workers on BCC and lentigo maligna melanoma.
authors.affiliation: Abteilung Klinische Sozialmedizin, Berufs- und Umweltdermatologie, Ruprecht-Karls-Universität Heidelberg, Thibautstr. 3, 69115, Heidelberg, Deutschland. thomas.diepgen@med.uni-heidelberg.de
authors.forename: T L
authors.initials: TL
authors.lastname: Diepgen
authors.forename: H
authors.initials: H
authors.lastname: Drexler
authors.forename: J
authors.initials: J
authors.lastname: Schmitt
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology*; D009784:Occupational Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000517:prevention & control; D016273:Occupational Exposure / Q000706:statistics & numerical data*; D015995:Prevalence; D012307:Risk Factors; D012878:Skin Neoplasms / Q000453:epidemiology*; D014466:Ultraviolet Rays; D055815:Young Adult