title: Papular epidermal nevus with "skyline" basal cell layer (PENS) with extracutaneous findings.
abstract: Papular epidermal nevus with "skyline" basal cell layer (PENS), a variant of epidermal nevus, was recently described in otherwise normal children. We describe herein a patient with multiple, typical PENS lesions associated with peculiar facies, bilateral Achilles tendon shortening, and mild psychomotor delay. The association of PENS with extracutaneous manifestations suggests the possibility of a new type of epidermal nevus syndrome, for which we propose the term PENS syndrome.
authors.affiliation: Department of Dermatology, Hospital de Cabueñes, Gijón, Spain.
authors.forename: Eloy
authors.initials: E
authors.lastname: Rodríguez-Díaz
authors.forename: Pablo
authors.initials: P
authors.lastname: Gonzalvo
authors.forename: Isabel
authors.initials: I
authors.lastname: Colmenero
authors.forename: Luis
authors.initials: L
authors.lastname: Requena
authors.forename: Angela
authors.initials: A
authors.lastname: Hernández-Martín
authors.forename: Antonio
authors.initials: A
authors.lastname: Torrelo
mesh_terms: D000125:Achilles Tendon / Q000002:abnormalities*; D000293:Adolescent; D004817:Epidermis / Q000473:pathology*; D019066:Facies; D006801:Humans; D008297:Male; D009506:Nevus; D009508:Nevus, Pigmented / Q000175:diagnosis*; D011596:Psychomotor Disorders / Q000175:diagnosis*; D012878:Skin Neoplasms / Q000175:diagnosis*; D013577:Syndrome; D009626:Terminology as Topic