title: Influenza A H1N1/2009 infection in pediatric solid organ transplant recipients.
abstract: OBJECTIVE
  The aim of this study was to describe the clinical characteristics and outcome of pandemic influenza A H1N1/2009 (pH1N1) infection, in a retrospective cohort of pediatric patients with kidney and/or liver transplant and confirmed pH1N1 infection from June to December 2009, diagnosed in 2 Spanish teaching hospitals.
  
  
  RESULTS
  Forty-nine patients were included. Pneumonia was diagnosed in 4 patients (8.2%), and 3 of them required respiratory support. There were no related deaths.
  
  
  CONCLUSIONS
  Antiviral treatment within 48 h was associated with a lower likelihood of pneumonia (0/38, 0%) than treatment started after 48 h (4/11, 36.3%) (P < 0.01).
authors.affiliation: Department of Infectious Diseases, Hospital Universitari Vall d'Hebron, Barcelona, Spain; Spanish Network for Research in Infectious Diseases (REIPI), Spain. joan.gavalda@vhir.org
authors.forename: J
authors.initials: J
authors.lastname: Gavaldà
authors.forename: E
authors.initials: E
authors.lastname: Cabral
authors.forename: E
authors.initials: E
authors.lastname: Alonso
authors.forename: P
authors.initials: P
authors.lastname: Perez-Romero
authors.forename: A
authors.initials: A
authors.lastname: Pérez
authors.forename: J
authors.initials: J
authors.lastname: Quintero
authors.forename: M
authors.initials: M
authors.lastname: Campins
authors.forename: R
authors.initials: R
authors.lastname: Vilalta
authors.forename: A
authors.initials: A
authors.lastname: Alonso
authors.forename: O
authors.initials: O
authors.lastname: Len
authors.forename: M
authors.initials: M
authors.lastname: Navarro
authors.forename: J
authors.initials: J
authors.lastname: Nieto
authors.forename: P
authors.initials: P
authors.lastname: Jara
authors.forename: R
authors.initials: R
authors.lastname: Charco
authors.forename: A
authors.initials: A
authors.lastname: Pahissa
authors.forename: E
authors.initials: E
authors.lastname: Cordero
mesh_terms: D000293:Adolescent; D000998:Antiviral Agents / Q000627:therapeutic use*; D002648:Child; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D053118:Influenza A Virus, H1N1 Subtype; D007251:Influenza, Human / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D016030:Kidney Transplantation / Q000009:adverse effects*; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D058873:Pandemics; D011014:Pneumonia / Q000209:etiology; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology
chemical_list: D000998:Antiviral Agents