title: A case of Histoplasma capsulatum endophthalmitis diagnosed in Italy.
abstract: Histoplasma capsulatum var. capsulatum is a dimorphic fungus endemic in the eastern United States and most countries of Latin America. Sporadic cases of histoplasmosis have been reported in Europe, mainly in immigrants or people returning from highly endemic areas. We report a case of 64-year-old Italian man with endophthalmitis, an unusual presentation of H. capsulatum infection. The patient shows redness, blurred vision, localized pain in the right eye. H. capsulatum was cultured from a vitreous biopsy and yeast forms were seen at histology.
authors.affiliation: Fondazione IRCCS Cà-Granda Ospedale Maggiore Policlinico, Via F. Sforza 35, Milan, Italy. anna.grancini@libero.it
authors.forename: Anna
authors.initials: A
authors.lastname: Grancini
authors.forename: Manuela
authors.initials: M
authors.lastname: Colosimo
authors.forename: Chiara
authors.initials: C
authors.lastname: Mapelli
authors.forename: Massimo
authors.initials: M
authors.lastname: Cogliati
authors.forename: Francesco
authors.initials: F
authors.lastname: Pallotti
authors.forename: Romualdo
authors.initials: R
authors.lastname: Grande
authors.forename: Erminio
authors.initials: E
authors.lastname: Torresani
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Tortorano
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000008:administration & dosage; D000935:Antifungal Agents / Q000008:administration & dosage*; D009877:Endophthalmitis / Q000382:microbiology / Q000473:pathology*; D017809:Fatal Outcome; D015725:Fluconazole / Q000008:administration & dosage; D006658:Histoplasma / Q000302:isolation & purification*; D006660:Histoplasmosis / Q000382:microbiology / Q000473:pathology*; D006801:Humans; D007558:Italy; D017964:Itraconazole / Q000008:administration & dosage; D008297:Male; D014821:Vitrectomy
chemical_list: D000935:Antifungal Agents; C068538:liposomal amphotericin B; D017964:Itraconazole; D000666:Amphotericin B; D015725:Fluconazole