title: Who would use PrEP? Factors associated with intention to use among MSM in London: a community survey.
abstract: OBJECTIVE
  To assess current and intended future use of pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM) and characterise those attending sexual health clinics, the anticipated PrEP delivery setting.
  
  
  METHODS
  Cross-sectional study.
  
  
  METHODS
  Self-administered survey of 842 HIV negative MSM recruited from social venues in London in 2011.
  
  
  RESULTS
  One in 10 (10.2%, 83/814, 95% CI 8.2% to 12.5%) and one in 50 (2.1%, 17/809, 95% CI 1.2% to 3.3%) reported having ever used post-exposure prophylaxis (PEP) and PrEP respectively. Half reported they would be likely to use PrEP if it became available as a daily pill (50.3%, 386/786, 95% CI 46.7% to 53.9%). MSM were more likely to consider future PrEP use if they were <35 years (adjusted OR (AOR) 1.57, 95% CI 1.16 to 2.14), had unprotected anal intercourse with casual partners (AOR 1.70, 95% CI 1.13 to 2.56), and had previously used PEP (AOR 1.94, 95% CI 1.17 to 3.24). Over half of MSM (54.8% 457/834 95% CI 51.3 to 58.2) attended a sexual health clinic the previous year. Independent factors associated with attendance were age <35 (AOR 2.29, 95% CI 1.68 to 3.13), and ≥ 10 anal sex partners in the last year (AOR 2.49, 95% CI 1.77 to 3.52).
  
  
  CONCLUSIONS
  The concept of PrEP for HIV prevention in the form of a daily pill is acceptable to half of sexually active MSM in London. MSM reporting higher risk behaviours attend sexual health clinics suggesting this is a suitable setting for PrEP delivery.
authors.affiliation: HIV and STI Department, Health Protection Agency-Colindale, London NW9 5EQ, UK; adamma.aghaizu@hpa.org.uk.
authors.forename: Adamma
authors.initials: A
authors.lastname: Aghaizu
authors.forename: Danielle
authors.initials: D
authors.lastname: Mercey
authors.forename: Andrew
authors.initials: A
authors.lastname: Copas
authors.forename: Anne M
authors.initials: AM
authors.lastname: Johnson
authors.forename: Graham
authors.initials: G
authors.lastname: Hart
authors.forename: Anthony
authors.initials: A
authors.lastname: Nardone
mesh_terms: D000328:Adult; D000368:Aged; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D018890:Chemoprevention / Q000379:methods*; D003625:Data Collection; D015658:HIV Infections / Q000517:prevention & control*; D018451:Homosexuality, Male; D006801:Humans; D008131:London; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents