title: [Dysfunction of the Eustachian tube and endothelial dysfunction: the present view of the problem (Part 1)].
abstract: This paper is focused on the topical otorhinolaryngological problem of Eustachian tube dysfunction, a pathological condition preceding or accompanying exudative otitis media. Based on the results of modern fundamental research, the author considers for the first time the role of endotoxins of Gram-negative microorganisms and endothelial dysfunction in etiology and pathogenesis of tubal disorders, exudative otitis media, and the related complications of sensorineural impairment of hearing.
authors.forename: N A
authors.initials: NA
authors.lastname: Petukhova
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000075202:Contraindications; D019468:Disease Management; D018450:Disease Progression; D004727:Endothelium / Q000503:physiopathology; D004731:Endotoxins; D005064:Eustachian Tube / Q000503:physiopathology*; D006090:Gram-Negative Bacteria / Q000472:pathogenicity*; D006319:Hearing Loss, Sensorineural / Q000209:etiology; D006801:Humans; D010034:Otitis Media with Effusion / Q000145:classification / Q000150:complications / Q000382:microbiology / Q000503:physiopathology
chemical_list: D000900:Anti-Bacterial Agents; D004731:Endotoxins