title: Anamnestic immunological response profile in laboratory animals after immunization with recombinant hepatitis B vaccines of different generations.
abstract: Hepatitis B vaccines containing preS1 and preS2 fragments are assumed to be more immunogenic than those containing SHBs protein alone, which may be of importance for immunization of people with poorly induced or without any immunological response after vaccination. The aim of this study was to evaluate: The following conclusions can be drawn on the basis of obtained results:
authors.affiliation: National Institute of Public Health - National Institute of Hygiene, Department of Sera and Vaccines Evaluation, Chocimska Str. 24, 00-791 Warsaw, Poland. pgorska@pzh.gov.pl
authors.forename: Paulina
authors.initials: P
authors.lastname: Górska
authors.forename: Jacek
authors.initials: J
authors.lastname: Michałkiewicz
authors.forename: Bożenna
authors.initials: B
authors.lastname: Bucholc
mesh_terms: D000818:Animals; D016207:Cytokines / Q000096:biosynthesis; D006508:Hepatitis Antibodies / Q000096:biosynthesis; D017325:Hepatitis B Vaccines / Q000276:immunology*; D007111:Immunity, Cellular; D007156:Immunologic Memory; D051379:Mice; D008807:Mice, Inbred BALB C; D014614:Vaccines, Synthetic / Q000276:immunology*
chemical_list: D016207:Cytokines; D006508:Hepatitis Antibodies; D017325:Hepatitis B Vaccines; D014614:Vaccines, Synthetic