title: [Leprosy-like cutaneous presentation of Histoplasma capsulatum infection in an African HIV+ patient].
abstract: Histoplasma capsulatum is an opportunistic dimorphic fungus responsible for most often self-limiting or flu-like infections but potentially lethal in immunocompromised hosts. Histoplasmosis is rare in Europe. We reported a case of disseminated histoplasmosis in an African HIV patient with a leprosy-like primary cutaneous presentation and involvement of lungs, brain, limphnodes and eye. The therapy with liposomial B amphotericin and itraconazole led to a prompt resolution of the symptoms.
authors.affiliation: Dipartimento di Scienze per la Promozione della Salute, Sezione di Malattie Infettive, Universita di Palermo, Palermo, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Scarlata
authors.forename: Claudia
authors.initials: C
authors.lastname: Imburgia
authors.forename: Marcello
authors.initials: M
authors.lastname: Trizzino
authors.forename: Lucina
authors.initials: L
authors.lastname: Titone
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000382:microbiology*; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D003881:Dermatomycoses / Q000175:diagnosis* / Q000382:microbiology; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005869:Ghana; D006679:HIV Seropositivity / Q000150:complications*; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D016867:Immunocompromised Host; D007558:Italy; D017964:Itraconazole / Q000627:therapeutic use; D007918:Leprosy / Q000175:diagnosis; D008297:Male; D012867:Skin / Q000382:microbiology* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B