title: A history of HbA1c through Clinical Chemistry and Laboratory Medicine.
abstract: HbA(1c) was discovered in the late 1960s and its use as marker of glycemic control has gradually increased over the course of the last four decades. Recognized as the gold standard of diabetic survey, this parameter was successfully implemented in clinical practice in the 1970s and 1980s and internationally standardized in the 1990s and 2000s. The use of standardized and well-controlled methods, with well-defined performance criteria, has recently opened new directions for HbA(1c) use in patient care, e.g., for diabetes diagnosis. Many reports devoted to HbA1c have been published in Clinical Chemistry and Laboratory Medicine (CCLM) journal. This review reminds the major steps of HbA(1c) history, with a special emphasis on the contribution of CCLM in this field.
authors.affiliation: Laboratory of Pediatric Biology and Research, American Memorial Hospital, CHU of Reims, Reims, France. pgillery@chu-reims.fr
authors.forename: Philippe
authors.initials: P
authors.lastname: Gillery
mesh_terms: D002624:Chemistry, Clinical / Q000266:history*; D019411:Clinical Laboratory Techniques / Q000266:history*; D015510:Clinical Medicine / Q000266:history*; D006442:Glycated Hemoglobin / Q000266:history*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans
chemical_list: D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human