title: [Telangiectatic osteosarcoma secondary to a liposclerosing myxofibrous tumor: a case report].
abstract: Malignant transformation of a fibrous dysplasia into an osteosarcoma is very rare. We report the case of an 84-year-old man with telangiectatic osteosarcoma of the upper femur arising in a previous fibrous dysplasia also known as liposclerosing myxofibrous tumor. The tumor was expressing the epithelial membrane antigen. This is the first described case of a malignant transformation into an osteosarcoma arising in a liposclerosing myxofibrous tumor. We discuss the main differential diagnosis with a review.
authors.affiliation: Service d'anatomie pathologique et histologie-cytologie, CHU de Rangueil, 1, avenue du Professeur-Jean-Poulhès, TSA 50032, 31059 Toulouse cedex 9, France. claire.illac@gmail.com
authors.forename: Claire
authors.initials: C
authors.lastname: Illac
authors.forename: Marie-Bernadette
authors.initials: MB
authors.lastname: Delisle
authors.forename: Paul
authors.initials: P
authors.lastname: Bonnevialle
authors.forename: Hélène
authors.initials: H
authors.lastname: Chiavassa-Gandois
authors.forename: Gonzague
authors.initials: G
authors.lastname: de Pinieux
authors.forename: Anne
authors.initials: A
authors.lastname: Gomez-Brouchet
mesh_terms: D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000032:analysis; D001845:Bone Cysts / Q000209:etiology / Q000473:pathology; D003937:Diagnosis, Differential; D018450:Disease Progression; D005266:Femoral Neoplasms / Q000098:blood supply / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D005357:Fibrous Dysplasia of Bone; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D018396:Mucin-1 / Q000032:analysis; D016609:Neoplasms, Second Primary / Q000098:blood supply / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D012516:Osteosarcoma / Q000098:blood supply / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D054364:Solitary Fibrous Tumors / Q000737:chemistry / Q000473:pathology*; D013684:Telangiectasis / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor; D018396:Mucin-1