title: Cascade imaging of proteolytic pathways in cancer cells using fluorescent protein-conjugated gold nanoquenchers.
abstract: The real-time monitoring of the caspase cascade in cancer cells during apoptosis was performed using various caspase substrate-linked fluorescent proteins-conjugated gold nanoparticles as a new imaging probe.
authors.affiliation: BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Major of Nanobiotechnology, University of Science and Technology, Gwahangno, Yuseong, Daejeon 305-806, Republic of Korea.
authors.forename: Kyoungsook
authors.initials: K
authors.lastname: Park
authors.forename: Jinyoung
authors.initials: J
authors.lastname: Jeong
authors.forename: Bong Hyun
authors.initials: BH
authors.lastname: Chung
mesh_terms: D017209:Apoptosis; D053148:Caspase 3 / Q000378:metabolism*; D002470:Cell Survival / Q000187:drug effects; D006046:Gold / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D008164:Luminescent Proteins / Q000737:chemistry* / Q000378:metabolism; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000633:toxicity; D008856:Microscopy, Fluorescence; D013302:Streptomyces / Q000187:drug effects
chemical_list: D008164:Luminescent Proteins; D006046:Gold; D053148:Caspase 3