title: Pelvic organ support, symptoms and quality of life during pregnancy: a prospective study.
abstract: OBJECTIVE
  Prevalence studies show an increase in lower urinary tract and pelvic floor symptoms during pregnancy. The aim of our prospective study was to evaluate changes in pelvic organ support, pelvic floor symptoms and their effect on quality of life (QOL) during the first pregnancy using validated measures. We hypothesised that pregnancy is associated with worsening of pelvic floor function.
  
  
  METHODS
  Objective assessment of pelvic organ support using the Pelvic Organ Prolapse Quantification (POP-Q) system and subjective evaluation of symptoms of pelvic floor disorders and related QOL with the electronic Personal Assessment Questionnaire-Pelvic Floor (ePAQ-PF) were performed in the second trimester and then repeated at 36 weeks gestation.
  
  
  RESULTS
  A total of 182 nulliparae attended the first visit at 20 weeks and 150 (82.4%) women returned for follow-up at 36 weeks gestation. There were no significant changes in POP-Q points or stage between the two visits except for a significant increase in genital hiatus (p = 0.0001) and perineal body length (p = 0.0001). The vaginal symptoms did not show any changes. Symptoms and bother with voiding difficulties and stress urinary incontinence increased during pregnancy. Constipation (p = 0.02) and evacuation subdomains improved significantly (p = 0.009). In the sexual domain, the only subdomain that worsened significantly (p = 0.03) was "sex and vaginal symptoms". None of the pelvic floor symptoms impacted the QOL.
  
  
  CONCLUSIONS
  In our group of nulliparae, pelvic floor-related QOL and prolapse stage did not change significantly from the second to the third trimester of pregnancy.
authors.affiliation: Department of Obstetrics and Gynaecology, University Hospital of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.
authors.forename: Ksenia
authors.initials: K
authors.lastname: Elenskaia
authors.forename: Ranee
authors.initials: R
authors.lastname: Thakar
authors.forename: Abdul H
authors.initials: AH
authors.lastname: Sultan
authors.forename: Inka
authors.initials: I
authors.lastname: Scheer
authors.forename: Joseph
authors.initials: J
authors.lastname: Onwude
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D010298:Parity; D017773:Pelvic Floor / Q000502:physiology*; D011247:Pregnancy / Q000502:physiology*; D011446:Prospective Studies; D011788:Quality of Life; D055815:Young Adult