title: A case report: Multaq-induced leukocytoclastic vasculitis.
abstract: A 71-year-old white male presented to the emergency department complaining of a worsening lower extremity rash. Thirteen days before presentation, the patient was placed on Multaq (dronedarone) for his paroxysmal atrial fibrillation. Biopsy-proven leukocytoclastic vasculitis (LV) was diagnosed, and causes for the condition other than drug-induced were investigated and ruled out. Rash has been cited as a possible side effect of Multaq; however, a literature search has revealed this to be the first documented case of likely multaq-induced LV. Other patients on Multaq therapy should be monitored for signs and symptoms of LV and be referred to an acute care setting as indicated.
authors.affiliation: 1Department of Radiology, Detroit Medical Center, Wayne State University, Detroit, MI 2Department of Internal Medicine and Cardiology, Mercy Catholic Medical Center, Darby, PA 3Department of Radiology, Huron Valley-Sinai Hospital, Commerce, MI.
authors.forename: Suzanne M
authors.initials: SM
authors.lastname: Smith
authors.forename: Mohammed
authors.initials: M
authors.lastname: Al-Bataineh
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Iorfido
authors.forename: Jarrod
authors.initials: J
authors.lastname: Macfarlane
mesh_terms: D000368:Aged; D000638:Amiodarone / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000188:drug therapy; D001706:Biopsy; D000077764:Dronedarone; D006801:Humans; D035002:Lower Extremity; D008297:Male; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000139:chemically induced* / Q000473:pathology
chemical_list: D000889:Anti-Arrhythmia Agents; D000077764:Dronedarone; D000638:Amiodarone