title: Disease mechanisms in MS: the potassium channel KIR4.1--a potential autoantigen in MS.
abstract: Multiple sclerosis is an inflammatory, demyelinating disease in which antigens of the myelin sheath have been considered the autoimmune target. A recent study suggests that the potassium channel KIR4.1 is another potential autoantigen in some patients with multiple sclerosis, and might also be a target in other demyelinating diseases.
authors.affiliation: Department of Neurology, Ohio State University, Columbus, OH 43210, USA. michael.racke@osumc.edu
authors.forename: Michael K
authors.initials: MK
authors.lastname: Racke
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000096:biosynthesis*; D001324:Autoantigens / Q000276:immunology*; D006801:Humans; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000276:immunology*; D024661:Potassium Channels, Inwardly Rectifying / Q000276:immunology*; D000098854:Kcnj10 Channel
chemical_list: D001323:Autoantibodies; D001324:Autoantigens; D000098854:Kcnj10 Channel; D024661:Potassium Channels, Inwardly Rectifying