title: Briareolate esters from the gorgonian Briareum asbestinum.
abstract: Two new briarane diterpenoids briareolate esters J (1) and K (2) were isolated from the methanolic extract of the octocoral Briareum asbestinum collected off the coast of Boca Raton, Florida. The structures of briaranes 1 and 2 were elucidated by interpretation of spectroscopic data. Briareolate ester K (2) showed weak growth inhibition activity against human embryonic stem cells (BG02).
authors.affiliation: Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL 33431, USA.
authors.forename: Rian J
authors.initials: RJ
authors.lastname: Meginley
authors.affiliation: Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL 33431, USA.
authors.forename: Prasoon
authors.initials: P
authors.lastname: Gupta
authors.affiliation: Viacyte Inc., 111 Riverbend Rd, Athens, GA 30602, USA.
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Schulz
authors.affiliation: Department of Biochemistry and Molecular Biology, The University of Georgia, Athens, GA 30602, USA.
authors.forename: Amanda B
authors.initials: AB
authors.lastname: McLean
authors.affiliation: Viacyte Inc., 111 Riverbend Rd, Athens, GA 30602, USA.
authors.forename: Allan J
authors.initials: AJ
authors.lastname: Robins
authors.affiliation: Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL 33431, USA.
authors.forename: Lyndon M
authors.initials: LM
authors.lastname: West
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D004224:Diterpenes / Q000302:isolation & purification / Q000494:pharmacology*; D053595:Embryonic Stem Cells / Q000187:drug effects* / Q000378:metabolism; D004952:Esters / Q000302:isolation & purification / Q000494:pharmacology*; D005431:Florida; D006801:Humans; D013057:Spectrum Analysis
chemical_list: D004224:Diterpenes; D004952:Esters