title: MYC addiction: a potential therapeutic target in MM.
abstract: In this issue of Blood, Holien et al report that MYC addiction is responsible for rapid death of myeloma cell lines and primary myeloma tumor cells treated with a specific MYC inhibitor.
authors.affiliation: National Cancer Institute; Mayo Clinic, Arizona.
authors.forename: W Michael
authors.initials: WM
authors.lastname: Kuehl
authors.forename: P Leif
authors.initials: PL
authors.lastname: Bergsagel
mesh_terms: D017209:Apoptosis / Q000187:drug effects*; D049109:Cell Proliferation / Q000187:drug effects*; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects*; D006801:Humans; D009101:Multiple Myeloma / Q000188:drug therapy* / Q000473:pathology*; D016271:Proto-Oncogene Proteins c-myc / Q000378:metabolism*
chemical_list: C489427:MYC protein, human; D016271:Proto-Oncogene Proteins c-myc