title: Hepatocyte hopping of OATP1B substrates contributes to efficient hepatic detoxification.
authors.affiliation: Division of Molecular Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
authors.forename: D
authors.initials: D
authors.lastname: Iusuf
authors.forename: E
authors.initials: E
authors.lastname: van de Steeg
authors.forename: A H
authors.initials: AH
authors.lastname: Schinkel
mesh_terms: D000818:Animals; D000838:Anions; D001692:Biological Transport; D002412:Cations; D064420:Drug-Related Side Effects and Adverse Reactions; D022781:Hepatocytes / Q000378:metabolism*; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D008099:Liver / Q000378:metabolism / Q000473:pathology; D027381:Liver-Specific Organic Anion Transporter 1; D027361:Organic Anion Transporters / Q000378:metabolism*; D029362:Organic Anion Transporters, Sodium-Independent / Q000378:metabolism*; D004364:Pharmaceutical Preparations / Q000737:chemistry / Q000378:metabolism*; D000074542:Solute Carrier Organic Anion Transporter Family Member 1B3
chemical_list: D000838:Anions; D002412:Cations; D027381:Liver-Specific Organic Anion Transporter 1; D027361:Organic Anion Transporters; D029362:Organic Anion Transporters, Sodium-Independent; D004364:Pharmaceutical Preparations; C503999:SLCO1B1 protein, human; C421209:SLCO1B3 protein, human; D000074542:Solute Carrier Organic Anion Transporter Family Member 1B3