title: Decreased hydrogen production leads to selective butanol production in co-cultures of Clostridium thermocellum and Clostridium saccharoperbutylacetonicum strain N1-4.
abstract: When Clostridium thermocellum and Clostridium saccharoperbutylacetonicum strain N1-4 were co-cultured hydrogen production decreased and butanol was selectively produced with extremely low level of acetone. Since the high butanol production correlates with low hydrogen production, the molecular selection of hydrogenase gene activity is expected to yield strains exhibiting a higher butanol ratio.
authors.affiliation: Department of Fermentation Science and Technology, Faculty of Applied Bioscience, Tokyo University of Agriculture, 1-1-1 Sakuragaoka, Setagaya-ku, Tokyo 156-8502, Japan. s3nakaya@nodai.ac.jp
authors.forename: Shunichi
authors.initials: S
authors.lastname: Nakayama
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Bando
authors.forename: Akihiro
authors.initials: A
authors.lastname: Ohnishi
authors.forename: Toshimori
authors.initials: T
authors.lastname: Kadokura
authors.forename: Atsumi
authors.initials: A
authors.lastname: Nakazato
mesh_terms: D000096:Acetone / Q000378:metabolism; D000440:Butanols / Q000378:metabolism*; D003013:Clostridium / Q000166:cytology* / Q000378:metabolism*; D048013:Acetivibrio thermocellus / Q000166:cytology / Q000378:metabolism*; D006859:Hydrogen / Q000378:metabolism*; D006864:Hydrogenase / Q000378:metabolism
chemical_list: D000440:Butanols; D000096:Acetone; D006859:Hydrogen; D006864:Hydrogenase