title: A case of synchronous metastasis of breast cancer to stomach and colon.
abstract: A case of synchronous metastasis of breast cancer to the stomach and colon is reported. A 38-year-old woman with a history of bilateral breast cancer was admitted for endoscopic examination because of occult blood. Endoscopic examination showed elevated lesions on the mucosal surface of the stomach and cecum. Histopathological examination of the biopsy specimens obtained from both sites showed adenocarcinoma, comprised of tumor cells with structural and nuclear atypia, which were similar to those of the primary breast cancer cells. In immunohistochemical analysis, these tumor cells stained positive for ER. Therefore, we diagnosed a synchronous metastasis of breast cancer to the stomach and colon. Synchronous metastasis of breast cancer to the stomach and colon without liver metastasis or peritoneal dissemination is extremely rare, with only 4 reported cases existing in literature.
authors.affiliation: Departments of Surgery, National Hospital Organization Beppu Medical Center, Beppu, Japan.
authors.forename: Hideya
authors.initials: H
authors.lastname: Takeuchi
authors.forename: Shozi
authors.initials: S
authors.lastname: Hiroshige
authors.forename: Yasuji
authors.initials: Y
authors.lastname: Yoshikawa
authors.forename: Tetusya
authors.initials: T
authors.lastname: Kusumoto
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Muto
mesh_terms: D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000473:pathology*; D003110:Colonic Neoplasms / Q000556:secondary*; D005260:Female; D006801:Humans; D013274:Stomach Neoplasms / Q000556:secondary*