title: Plant uptake of pharmaceutical chemicals detected in recycled organic manure and reclaimed wastewater.
abstract: Land application of recycled manure produced from biosolids and reclaimed wastewater can transfer pharmaceutical chemicals to terrestrial environments, giving rise to potential accumulation of these residues in edible plants. In this study, the potential for plant uptake of 13 pharmaceutical chemicals, and the relation between the accumulation features within the plant and the physicochemical properties were examined by exposing pea and cucumber to an aqueous solution containing pharmaceutical chemicals. Ten of 13 compounds tested were detected in plant leaves and stems. Comparison of the plant uptake characteristics and the octanol-water partition coefficient of pharmaceutical chemicals showed that compounds with an intermediate polarity such as carbamazepine and crotamiton could be easily transported to plant shoots. Moreover, these results suggest the possibility of highly hydrophilic pharmaceutical chemicals such as trimethoprim and sulfonamides to be accumulated in plant roots owing to their low permeability in root cell membranes.
authors.affiliation: Center for Marine Environmental Studies (CMES), Ehime University, Matsuyama, Ehime, Japan.
authors.forename: Rumi
authors.initials: R
authors.lastname: Tanoue
authors.forename: Yuri
authors.initials: Y
authors.lastname: Sato
authors.forename: Miki
authors.initials: M
authors.lastname: Motoyama
authors.forename: Shuhei
authors.initials: S
authors.lastname: Nakagawa
authors.forename: Ryota
authors.initials: R
authors.lastname: Shinohara
authors.forename: Kei
authors.initials: K
authors.lastname: Nomiyama
mesh_terms: D055598:Chemical Phenomena; D018553:Cucumis sativus / Q000378:metabolism; D008372:Manure / Q000032:analysis*; D058871:Organic Agriculture; D018532:Pisum sativum / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism*; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010945:Plants, Edible / Q000737:chemistry / Q000378:metabolism*; D059027:Recycling; D012996:Solutions; D013329:Structure-Activity Relationship; D062065:Wastewater / Q000737:chemistry*; D014867:Water
chemical_list: D008372:Manure; D004364:Pharmaceutical Preparations; D012996:Solutions; D062065:Wastewater; D014867:Water