title: Novel antihypertensive therapies: renal sympathetic nerve ablation and carotid baroreceptor stimulation.
abstract: Therapeutic interventions aimed at reducing high blood pressure still encompass a number of difficulties and limitations. This is the case particularly in resistant hypertension, i.e. a condition characterized by a very high cardiovascular risk. Carotid baroreceptor stimulation and renal sympathetic nerves ablation represent new approaches in the treatment of this condition. This paper will provide a comparison of the effects of the two procedures, highlighting their effects on blood pressure, metabolic profile, target organ damage, safety and tolerability profile.
authors.affiliation: Clinica Medica, Department of Clinical Medicine and Prevention, University of Milano-Bicocca, Monza, MI, Italy. guido.grassi@unimib.it
authors.forename: Guido
authors.initials: G
authors.lastname: Grassi
authors.forename: Gino
authors.initials: G
authors.lastname: Seravalle
authors.forename: Gianmaria
authors.initials: G
authors.lastname: Brambilla
authors.forename: Michele
authors.initials: M
authors.lastname: Bombelli
authors.forename: Raffaella
authors.initials: R
authors.lastname: Dell'Oro
authors.forename: Edoardo
authors.initials: E
authors.lastname: Gronda
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Mancia
mesh_terms: D002346:Carotid Sinus / Q000601:surgery; D004599:Electric Stimulation Therapy; D006801:Humans; D006973:Hypertension / Q000628:therapy*; D007668:Kidney / Q000294:innervation / Q000601:surgery; D011311:Pressoreceptors / Q000601:surgery; D013562:Sympathectomy