title: Impact of geriatric conditions versus medical diagnoses on ADL disability among nonagenarians and centenarians.
abstract: OBJECTIVE
  The authors investigated the relationship of activities of daily living (ADL) disability with medical diseases and geriatric conditions among nonagenarians and centenarians.
  
  
  METHODS
  Cross-sectional, n = 870 Chinese (age range: 90-108 years). Self-reported medical diseases and geriatric-specific conditions were obtained by face-to-face interviews. Biomedical measurements included systolic/diastolic blood pressure, BMI (body mass index), albumin, fasting glucose, creatinine clearance, hemoglobin, and lipid panel.
  
  
  RESULTS
  In bivariate analyses, 4 of 7 geriatric conditions (hearing problems, falls, cognitive impairment, fracture), and 6 of 11 biomedical measurements (fasting glucose, cholesterol, LDL, creatinine clearance, hemoglobin, albumin), but none of 10 medical diseases and no degree of comorbidities, were associated with ADL disability. In four different multivariate logistic regression models, two geriatric conditions (impaired cognition, fracture) were significant in three models, respiratory disease in one model, and fasting glucose in two models.
  
  
  CONCLUSIONS
  This study emphasizes the importance of geriatric conditions and their association with ADL disability among the oldest-old adult population.
authors.affiliation: West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Hongmei
authors.initials: H
authors.lastname: Wu
authors.forename: Joseph
authors.initials: J
authors.lastname: Flaherty
authors.forename: Birong
authors.initials: B
authors.lastname: Dong
authors.forename: Guanjian
authors.initials: G
authors.lastname: Liu
authors.forename: Juelin
authors.initials: J
authors.lastname: Deng
authors.forename: Yanling
authors.initials: Y
authors.lastname: Zhang
authors.forename: Jinhui
authors.initials: J
authors.lastname: Wu
authors.forename: Guo
authors.initials: G
authors.lastname: Zeng
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Ren
authors.forename: Junmei
authors.initials: J
authors.lastname: Hu
authors.forename: Weili
authors.initials: W
authors.lastname: Wu
authors.forename: Theodore K
authors.initials: TK
authors.lastname: Malmstrom
mesh_terms: D000203:Activities of Daily Living; D000367:Age Factors; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D002681:China; D003430:Cross-Sectional Studies; D006233:Persons with Disabilities / Q000706:statistics & numerical data*; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D036301:Qualitative Research; D057566:Self Report