title: [Combination of compound Xuanju capsule and tamoxifen citrate for idiopathic oligozoospermia].
abstract: OBJECTIVE
  To evaluate the clinical effects of Compound Xuanju Capsule combined with tamoxifen citrate on the seminal parameters of men with idiopathic oligozoospermia.
  
  
  METHODS
  We equally assigned 120 men with idiopathic oligozoospermia to receive Compound Xuanju Capsule plus tamoxifen citrate (experiment group) or tamoxifen citrate alone (control group). After 3 months of medication, we compared the concentration and total number of sperm with the baseline, and analyzed the influence of the duration of natural infertility on the therapeutic effect.
  
  
  RESULTS
  Both the concentration and total number of sperm were significantly increased in both the experiment and the control groups after 3 months of medication as compared with the baseline (P < 0.05), and the increases were even more significant in the former than in the latter group (P < 0.05). The therapeutic efficacy was remarkably better in the patients with natural infertility < or = years than in those > 3 years (P < 0.05).
  
  
  CONCLUSIONS
  Compound Xuanju Capsule combined with tamoxifen citrate produces satisfactory results in the treatment of idiopathic oligozoospermia, and therefore can be used as a first-line therapy for this disease.
authors.affiliation: Department of Andrology and Sexology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China. zhangxun19781004@163.com
authors.forename: Xun
authors.initials: X
authors.lastname: Zhang
authors.forename: Ji-Hong
authors.initials: JH
authors.lastname: Liang
authors.forename: Shi-Kun
authors.initials: SK
authors.lastname: Liang
authors.forename: Guo-Qiang
authors.initials: GQ
authors.lastname: Wei
authors.forename: Chun-Hui
authors.initials: CH
authors.lastname: Zhu
authors.forename: Wei-Ru
authors.initials: WR
authors.lastname: Song
authors.forename: Guang-Yu
authors.initials: GY
authors.lastname: Li
mesh_terms: D000328:Adult; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000188:drug therapy*; D008517:Phytotherapy; D013629:Tamoxifen / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D004365:Drugs, Chinese Herbal; D013629:Tamoxifen