title: [Disseminated nocardiosis in a patient with haemophilia: a problem of differential diagnosis].
abstract: Nocardia is found worldwide in soils and dust. In immunocompromised patients the lungs appear to be the most common initial site of infection due to  the inhalation of free living organisms. Nocardia asteroides is the most commonly isolated pathogenic Nocardia species. Pulmonary nocardiosis may mimic tuberculosis, staphylococcal or mycotic infections. Disseminated disease mainly occurs in immunocompromised patients with underlying illnesses such as chronic granulomatous disease, human immunodeficiency virus (HIV) infection, in patients undergoing cytotoxic chemotherapy, organ transplantation or prolonged glucocorticoid treatment. Subcutaneous infection occurs from trauma related inoculation of the organism. The Authors describe a clinical case regarding a patient with acquired haemophilia A, admitted to the hospital because of disseminated nocardiosis mimicking a neoplastic disease. He recovered completely after the antibiotic treatment.
authors.affiliation: U.O. Malattie Infettive Azienda Ospedaliera Carlo Poma, Mantova, Italy.
authors.forename: Gianni
authors.initials: G
authors.lastname: Gattuso
authors.forename: Donatella
authors.initials: D
authors.lastname: Tomasoni
authors.forename: Alfredo
authors.initials: A
authors.lastname: Scalzini
authors.forename: Paolo
authors.initials: P
authors.lastname: Costa
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D016867:Immunocompromised Host; D007297:Inpatients; D008297:Male; D008875:Middle Aged; D009617:Nocardia Infections / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D009616:Nocardia asteroides / Q000302:isolation & purification*; D009894:Opportunistic Infections / Q000150:complications*; D010397:Penicillanic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D010878:Piperacillin / Q000627:therapeutic use; D000078142:Tazobactam; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D010397:Penicillanic Acid; D000078142:Tazobactam; D010878:Piperacillin