title: Orchestrating hi-fi annotations.
abstract: By incorporating sequence homology and context associations, global probabilistic approaches to annotate genome-scale metabolic networks can substantially improve the accuracy of biochemical predictions, revealing potential functionality and directing experimental validation.
authors.affiliation: Pennsylvania State University, Department of Chemical Engineering, University Park, PA, USA.
authors.forename: Patrick F
authors.initials: PF
authors.lastname: Suthers
authors.forename: Costas D
authors.initials: CD
authors.lastname: Maranas
mesh_terms: D004798:Enzymes / Q000378:metabolism*; D053858:Metabolic Networks and Pathways; D011336:Probability
chemical_list: D004798:Enzymes