title: The first synthesis of Krempene B.
abstract: The synthesis of Krempene B, which can be isolated from the marine soft coral Cladiella krempfi, is achieved in 23.9% overall yield from commercially available 3β-acetoxy-5-pregnen-20-one by 11 steps. Key transformations include the dienone-phenol rearrangement of steroids and Wittig reaction.
authors.affiliation: College of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Key Laboratory of Development and Application of Forest Chemicals of Guangxi, Nanning 530006, China. liqunshen@126.com
authors.forename: Li-Qun
authors.initials: LQ
authors.lastname: Shen
authors.forename: Su-Yu
authors.initials: SY
authors.lastname: Huang
authors.forename: Yong
authors.initials: Y
authors.lastname: Tang
authors.forename: Fu-Hou
authors.initials: FH
authors.lastname: Lei
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D060326:Chemistry Techniques, Synthetic; D004224:Diterpenes / Q000138:chemical synthesis* / Q000737:chemistry; D013256:Steroids / Q000737:chemistry
chemical_list: D001688:Biological Products; D004224:Diterpenes; D013256:Steroids