title: The state of nanoparticle-based nanoscience and biotechnology: progress, promises, and challenges.
abstract: Colloidal nanoparticles (NPs) have become versatile building blocks in a wide variety of fields. Here, we discuss the state-of-the-art, current hot topics, and future directions based on the following aspects: narrow size-distribution NPs can exhibit protein-like properties; monodispersity of NPs is not always required; assembled NPs can exhibit collective behavior; NPs can be assembled one by one; there is more to be connected with NPs; NPs can be designed to be smart; surface-modified NPs can directly reach the cytosols of living cells.
authors.affiliation: Fachbereich Physik and WZMW, Philipps Universität Marburg, 35037 Marburg, Germany.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Pelaz
authors.forename: Sarah
authors.initials: S
authors.lastname: Jaber
authors.forename: Dorleta Jimenez
authors.initials: DJ
authors.lastname: de Aberasturi
authors.forename: Verena
authors.initials: V
authors.lastname: Wulf
authors.forename: Takuzo
authors.initials: T
authors.lastname: Aida
authors.forename: Jesús M
authors.initials: JM
authors.lastname: de la Fuente
authors.forename: Jochen
authors.initials: J
authors.lastname: Feldmann
authors.forename: Hermann E
authors.initials: HE
authors.lastname: Gaub
authors.forename: Lee
authors.initials: L
authors.lastname: Josephson
authors.forename: Cherie R
authors.initials: CR
authors.lastname: Kagan
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Kotov
authors.forename: Luis M
authors.initials: LM
authors.lastname: Liz-Marzán
authors.forename: Hedi
authors.initials: H
authors.lastname: Mattoussi
authors.forename: Paul
authors.initials: P
authors.lastname: Mulvaney
authors.forename: Christopher B
authors.initials: CB
authors.lastname: Murray
authors.forename: Andrey L
authors.initials: AL
authors.lastname: Rogach
authors.forename: Paul S
authors.initials: PS
authors.lastname: Weiss
authors.forename: Itamar
authors.initials: I
authors.lastname: Willner
authors.forename: Wolfgang J
authors.initials: WJ
authors.lastname: Parak
mesh_terms: D001709:Biotechnology / Q000639:trends*; D005544:Forecasting; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure*; D036103:Nanotechnology / Q000639:trends*; D012586:Science / Q000639:trends*