title: Glycosylations of cyclopropyl-modified carbohydrates: remarkable β-selectivity using a mannose building block.
abstract: A mannosyl donor bearing a spiroannulated cyclopropane unit at C-5 has been prepared, and its behavior in glycosylation reactions investigated. Selectivities in favor of the β-anomer were observed. Corresponding di- and trisaccharides incorporating the rigid cyclopropane motif were assembled.
authors.affiliation: Institut für Organische und Biomolekulare Chemie der Georg-August-Universität Göttingen, Tammannstr. 2, D-37077 Göttingen, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Brand
authors.forename: Katharina
authors.initials: K
authors.lastname: Kettelhoit
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Werz
mesh_terms: D003521:Cyclopropanes / Q000737:chemistry*; D004187:Disaccharides / Q000737:chemistry*; D006031:Glycosylation; D008358:Mannose / Q000737:chemistry*; D015394:Molecular Structure; D014312:Trisaccharides / Q000737:chemistry*
chemical_list: D003521:Cyclopropanes; D004187:Disaccharides; D014312:Trisaccharides; C030797:cyclopropane; D008358:Mannose