title: Relationship between psychiatric disorders and quality of life in nondialysis patients with chronic kidney disease.
abstract: BACKGROUND
  The aim of this study was to investigate the relationship between psychiatric disorders (anxiety and depression) and quality of life (QOL) in nondialysis patients with chronic kidney disease (CKD).
  
  
  METHODS
  QOL was evaluated in a sample of 57 nondialysis patients with CKD using the 36-item Short Form Health Survey questionnaire comprising 8 scales, including the physical component summary and mental component summary measures. Depression and anxiety were estimated using the Hamilton Depression Rating Scale and Hamilton Anxiety Rating Scale, respectively.
  
  
  RESULTS
  Depression and anxiety scores were negatively correlated with 7 of the 8 scales of the Short Form 36 questionnaire, and with the physical component summary and mental component summary scores, despite 38.6% patients with depression and 54.4% with anxiety, whereas QOL in the depression group, the anxiety group, and the anxiety and depression comorbid group was lower than that for those without the corresponding psychiatric disorders (P < 0.05).
  
  
  CONCLUSIONS
  This study demonstrates that depression and anxiety, commonly encountered in patients with CKD, could be a risk factor for QOL in these patients.
authors.affiliation: Department of Nephrology, Shandong University Qilu Hospital, Jinan, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Peng
authors.forename: Zhao
authors.initials: Z
authors.lastname: Hu
authors.forename: Ling
authors.initials: L
authors.lastname: Guo
authors.forename: Qing
authors.initials: Q
authors.lastname: Xia
authors.forename: Dengren
authors.initials: D
authors.lastname: Li
authors.forename: Xiangdong
authors.initials: X
authors.lastname: Yang
mesh_terms: D000368:Aged; D001008:Anxiety Disorders / Q000150:complications / Q000453:epidemiology / Q000523:psychology*; D003863:Depression / Q000150:complications / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D006435:Renal Dialysis; D051436:Renal Insufficiency, Chronic / Q000150:complications / Q000453:epidemiology / Q000523:psychology*; D011795:Surveys and Questionnaires