title: Metastases of esophageal carcinoma to skeletal muscle: single center experience.
abstract: Metastases of esophageal carcinoma to the skeletal muscle are rare, but the incidence may be increasing because of better diagnosis resulting from widespread use of positron emission tomography/computed tomography (PET/CT). A cohort of 205 patients with esophageal carcinoma treated at our center who had PET/CT between 2006 and 2010 was retrospectively evaluated for the presence of skeletal muscle metastases. Four patients had skeletal muscle metastases of esophageal carcinoma, including two patients with squamous cell carcinoma. In another patient with squamous cell carcinoma of the esophagus and synchronous skeletal muscle metastases, muscle metastases were subsequently shown to be related to second primary pancreatic adenocarcinoma. In all cases, skeletal muscle metastases were the first manifestation of systemic disease. In three patients palliation was obtained with the combination of external beam radiation therapy, systemic chemotherapy or surgical resection. Skeletal muscle metastases are a rare complication of esophageal carcinoma.
authors.affiliation: Department of Oncology, Palacký University Medical School and Teaching Hospital, 77520 Olomouc, Czech Republic.
authors.forename: Jan
authors.initials: J
authors.lastname: Cincibuch
authors.forename: Miroslav
authors.initials: M
authors.lastname: Mysliveček
authors.forename: Bohuslav
authors.initials: B
authors.lastname: Melichar
authors.forename: Cestmír
authors.initials: C
authors.lastname: Neoral
authors.forename: Iva
authors.initials: I
authors.lastname: Metelková
authors.forename: Michaela
authors.initials: M
authors.lastname: Zezulová
authors.forename: Hana
authors.initials: H
authors.lastname: Procházková-Študentová
authors.forename: Patrik
authors.initials: P
authors.lastname: Flodr
authors.forename: Miloslava
authors.initials: M
authors.lastname: Zlevorová
authors.forename: René
authors.initials: R
authors.lastname: Aujeský
authors.forename: Karel
authors.initials: K
authors.lastname: Cwiertka
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D019042:Muscle Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000628:therapy; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging / Q000473:pathology*; D010166:Palliative Care; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome