title: Characterization of three small supernumerary marker chromosomes (sSMC) in humans.
abstract: In the present study, three prenatally detected small supernumerary marker chromosomes (sSMC) were identified by banding cytogenetics and characterized in detail by molecular cytogenetics. In one case an sSMC(10) leading to a pericentric partial trisomy and in two cases heterochromatic sSMC derived from chromosome 22 were characterized. Outcomes were reportedly normal for two of the three cases for whom this information was known.
authors.affiliation: Nanjing Medical University Affiliated Suzhou Hospital, Suzhou Municipal Hospital, Jiangsu, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Ou
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Thomas
authors.initials: T
authors.lastname: Liehr
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Klein
authors.forename: Ahmed B
authors.initials: AB
authors.lastname: Hamid
authors.forename: Fuxin
authors.initials: F
authors.lastname: Wang
authors.forename: Chengying
authors.initials: C
authors.lastname: Duan
authors.forename: Hong
authors.initials: H
authors.lastname: Li
mesh_terms: D059786:Abnormal Karyotype; D000649:Amniocentesis; D025063:Chromosome Disorders / Q000175:diagnosis; D002879:Chromosomes, Human, Pair 10; D002892:Chromosomes, Human, Pair 22; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy