title: [Caffeoylquinic acid derivatives from the seeds of Vernonia anthelmintica].
abstract: Mature seeds of Vernonia anthelmintica were separated and purified by using such methods as macroporous absorption resin, Sephadex LH-20 and HPLC preparative chromatography. Six compounds were obtained and their structures were identified by such spectrum techniques as 1H, 13C-NMR and MS. Compound 1-6 were identified as caffeic acid (1), 3-O-caffeoylquinic acid (2), 4-O-caffeoylquinic acid (3), 5-O-caffeoylquinic acid (4), 3, 4-di-O-caffeoylisoquinic acid (5), 3, 4-di-O-caffeoylquinic acid (6). Among them, compounds 1-6 were separated from this plant for the first time, while compounds 3-5 were separated from this genus firstly.
authors.affiliation: Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China.
authors.forename: Yongxia
authors.initials: Y
authors.lastname: Wang
authors.forename: En
authors.initials: E
authors.lastname: Wang
authors.forename: Jing
authors.initials: J
authors.lastname: Shang
authors.forename: Hao
authors.initials: H
authors.lastname: Wang
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry; D011801:Quinic Acid / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D012639:Seeds / Q000737:chemistry*; D035741:Vernonia / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; C472707:caffeoylquinic acid; D011801:Quinic Acid