title: Early-onset breast cancer in a woman with Graves' disease.
abstract: The relationship between thyroid and breast diseases has been documented, but the clinical significance of Graves' disease and breast cancer is unclear. We present a young patient with a history of Graves' disease who developed a multicentric infiltrating ductal carcinoma of the breast several months after discontinuing her treatment with propylthiouracil. Early-onset breast cancer in women without a family history of early breast cancer may be related to hyperthyroidism. The relationship between thyroid hormone and estrogen is discussed.
authors.affiliation: Tulane University School of Medicine Changsha, China.
authors.forename: James E
authors.initials: JE
authors.lastname: Siegler
authors.forename: Xinying
authors.initials: X
authors.lastname: Li
authors.forename: Steven D
authors.initials: SD
authors.lastname: Jones
authors.forename: Emad
authors.initials: E
authors.lastname: Kandil