title: Primary lymphoepithelioma-like carcinoma of the lung: report of a rare case and review of the literature.
abstract: Primary lymphoepithelioma-like carcinoma of the lung is a rare type of non-small     cell lung carcinoma. In this study, we aimed to present a 62-year-old smoker     male with a primary lymphoepithelioma-like carcinoma of the hilar region of the     left lung. The patient underwent left pneumonectomy and no adjuvant therapy was     given. There were no other abnormalities on whole body PET/CT scan including the     nasopharyngeal region. The patient showed seropositivity for EBV IgG but     immunohistochemistry and PCR amplification studied on paraffin-embedded tissue     sections of the tumor failed to show any sign of EBV infection within the tumor     cells. He is alive and disease-free four months after the operation. Although     primary lymphoepithelioma-like carcinoma of the lung is usually reported in     young females with no history of tobacco use and the tumor cells are infected     with EBV, it may rarely be seen in elderly males with a history of tobacco use     and the tumor cells not infected with EBV.
authors.affiliation: Department of Pathology, Maltepe University, Faculty of Medicine, İstanbul, Turkey. nese.yener@yahoo.com
authors.forename: Neşe Arzu
authors.initials: NA
authors.lastname: Yener
authors.forename: Ahmet
authors.initials: A
authors.lastname: Balikçi
authors.forename: Rahmi
authors.initials: R
authors.lastname: Çubuk
authors.forename: Ahmet
authors.initials: A
authors.lastname: Mıdı
authors.forename: Alpay
authors.initials: A
authors.lastname: Örkı
authors.forename: Aynur
authors.initials: A
authors.lastname: Eren Topkaya
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D020031:Epstein-Barr Virus Infections / Q000150:complications; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012907:Smoking / Q000009:adverse effects