title: A matter of order: how E-selectin makes sweet contacts.
abstract: An entropy exclusive: Sialyl Lewis(x)  can be thought of as a "preorganized water oligomer". Recent research in the Ernst laboratory shows that the recognition of sialyl Lewis(x)  by E-selectin is exclusively entropy driven. This finding has implications for the design of carbohydrate-based drugs in general.
authors.affiliation: Institute of Chemistry, Center for Structural and Cell Biology in Medicine (CSCM), University of Luebeck, Ratzeburger Alle 160, 23562 Luebeck, Germany. thomas.peters@chemie.uni-luebeck.de
authors.forename: Thomas
authors.initials: T
authors.lastname: Peters
mesh_terms: D002236:Carbohydrate Conformation; D002241:Carbohydrates / Q000737:chemistry*; D019040:E-Selectin / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D002241:Carbohydrates; D019040:E-Selectin