title: Formulation and evaluation of herbal anti-acne moisturizer.
abstract: The moisture content present in human skin makes it look young and the use of moisturizer results in fastening the moisture with a surface film of oil. Acne vulgaris is one of the most commonly seen diseases among the youth. The present study is focused on the use of herbs as moisturizer for acne treatment. The anti-acne moisturizer was formulated from herbal crude extracts and investigated the physico-chemical parameters as well as antibacterial activity of the formulation. The study revealed that ethanol extract of Andrographis paniculata, Glycyrrhiza glabra, Ocimum sanctum, Azadiracta indica and Green tea possessed the potential for inhibiting acne. It was observed that the optimal formula of anti-acne moisturizer was satisfactorily effective to control acne inducing bacteria i.e., Staphylococcus epidermis and Propionibacterium. The physico-chemical parameters of the formulation were also optimal with no signs of irritation.
authors.affiliation: Department of Pharmaceutical Chemistry, Sree Vidyanikethan College of Pharmacy, Andhra Pradesh, India. arunrasheed@rediffmail.com
authors.forename: Arun
authors.initials: A
authors.lastname: Rasheed
authors.forename: Shaik Neelufar
authors.initials: SN
authors.lastname: Shama
authors.forename: Jyothi Mulanjananiyil
authors.initials: JM
authors.lastname: Joy
authors.forename: Bobbu Sravya
authors.initials: BS
authors.lastname: Reddy
authors.forename: Chirra
authors.initials: C
authors.lastname: Roja
mesh_terms: D000152:Acne Vulgaris / Q000382:microbiology / Q000517:prevention & control*; D000287:Administration, Topical; D035685:Andrographis; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D031601:Azadirachta; D028241:Camellia sinensis; D002626:Chemistry, Pharmaceutical; D052978:Disk Diffusion Antimicrobial Tests; D004355:Drug Stability; D004487:Edema / Q000139:chemically induced; D004643:Emollients / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D004890:Erythema / Q000139:chemically induced; D000431:Ethanol / Q000737:chemistry; D006035:Glycyrrhiza; D006801:Humans; D031339:Ocimum; D009824:Ointments; D028321:Plant Preparations / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D010946:Plants, Medicinal; D011424:Propionibacterium / Q000187:drug effects / Q000254:growth & development; D051381:Rats; D017208:Rats, Wistar; D012867:Skin / Q000187:drug effects*; D023422:Skin Irritancy Tests; D012997:Solvents / Q000737:chemistry; D013212:Staphylococcus epidermidis / Q000187:drug effects / Q000254:growth & development; D013678:Technology, Pharmaceutical / Q000379:methods; D014783:Viscosity
chemical_list: D000900:Anti-Bacterial Agents; D004643:Emollients; D009824:Ointments; D028321:Plant Preparations; D012997:Solvents; D000431:Ethanol