title: Endovascular therapy in children with acute ischemic stroke: review and recommendations.
abstract: This review provides a summary of the currently available data pertaining to the interventional management of acute ischemic stroke in children. The literature is scarce and is lacking much-needed prospective trials. No study in the literature on the well-established systemic or local thrombolysis trials has included children. Mechanical thrombectomy trials using clot retriever devices have also excluded patients younger than 18 years. The current review is limited to case series of interventional acute ischemic stroke therapy in children and the potential future of endovascular ischemic stroke therapy in this patient population. Recommendations in this review represent the opinion of the authors, based on review of the limited literature covering endovascular acute ischemic stroke therapy in children.
authors.affiliation: Division of Neurosurgery, The Hospital for Sick Children, University of Toronto, Toronto, Canada.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Ellis
authors.forename: Catherine
authors.initials: C
authors.lastname: Amlie-Lefond
authors.forename: Darren B
authors.initials: DB
authors.lastname: Orbach
mesh_terms: D000367:Age Factors; D000818:Animals; D002545:Brain Ischemia / Q000175:diagnosis / Q000628:therapy*; D002648:Child; D057510:Endovascular Procedures / Q000379:methods / Q000592:standards*; D006801:Humans; D017410:Practice Guidelines as Topic / Q000592:standards*; D020521:Stroke / Q000175:diagnosis / Q000628:therapy*; D015912:Thrombolytic Therapy / Q000379:methods / Q000592:standards*