title: Deciphering DNA-based asymmetric catalysis through intramolecular Friedel-Crafts alkylations.
abstract: We describe asymmetric intramolecular Friedel-Crafts alkylations with a DNA-based hybrid catalyst and propose a plausible binding model. This study shows promise for studying relationships between the helical chirality of DNA and enantioselectivity of the chemical reaction.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan.
authors.forename: Soyoung
authors.initials: S
authors.lastname: Park
authors.forename: Keiichi
authors.initials: K
authors.lastname: Ikehata
authors.forename: Ryo
authors.initials: R
authors.lastname: Watabe
authors.forename: Yuta
authors.initials: Y
authors.lastname: Hidaka
authors.forename: Arivazhagan
authors.initials: A
authors.lastname: Rajendran
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sugiyama
mesh_terms: D000478:Alkylation; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D004247:DNA / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: C560551:4,4'-dimethyl-2,2'-bipyridine; D009942:Organometallic Compounds; D011725:Pyridines; D003300:Copper; D004247:DNA