title: Topical application of 1% chlorhexidine gel versus 0.2% mouthwash in the treatment of peri-implant mucositis. An observational study.
abstract: OBJECTIVE
  The aim of this study was to compare the use of two chlorhexidine-based antimicrobial agents as an adjunct to mechanical therapy for the treatment of peri-implant mucositis.
  
  
  METHODS
  Thirty patients with peri-implant mucositis were included in the study and randomized in two groups. In addition to mechanical therapy, group A was treated with chlorhexidine 0.2% mouthwash, while group B was treated with chlorhexidine 1% gel. Probing depth, plaque index and bleeding index were recorded at each scheduled follow-up visit: ten days, 1 month and 3 months after giving the patients the assigned formulation. Patients had to fill in a questionnaire investigating their satisfaction and ease of use of the product.
  
  
  RESULTS
  A total of 23 patients (13 in group A and 10 in group B) attended all the follow-up visits. Chlorhexidine 0.2% mouthwash and chlorhexidine 1% gel were equally useful in the treatment of peri-implant mucositis leading to the reduction in inflammatory parameters. Probing depth decreased over time in both groups. Patients showed preference for gel formulation even if they found it more difficult to use.
  
  
  CONCLUSIONS
  Adjunctive treatment with different chlorhexidine formulations was beneficial to the treatment of peri-implant mucositis. Besides, no differences could be found between 0.2% mouthwash and 1% gel.
authors.affiliation: Universitá degli Studi di Milano, Department of Biomedical, Surgical and Dental Sciences, Research Centre in Oral Health, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
authors.forename: F
authors.initials: F
authors.lastname: De Siena
authors.forename: L
authors.initials: L
authors.lastname: Francetti
authors.forename: S
authors.initials: S
authors.lastname: Corbella
authors.forename: S
authors.initials: S
authors.lastname: Taschieri
authors.forename: M
authors.initials: M
authors.lastname: Del Fabbro
mesh_terms: D000368:Aged; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002710:Chlorhexidine / Q000008:administration & dosage*; D059605:Dental Implant-Abutment Design; D015921:Dental Implants / Q000009:adverse effects*; D003773:Dental Plaque / Q000188:drug therapy / Q000628:therapy; D003774:Dental Plaque Index; D012534:Dental Scaling; D005260:Female; D005500:Follow-Up Studies; D005782:Gels; D005884:Gingival Hemorrhage / Q000188:drug therapy / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes / Q000008:administration & dosage; D017060:Patient Satisfaction; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000188:drug therapy / Q000628:therapy; D013280:Stomatitis / Q000188:drug therapy* / Q000628:therapy
chemical_list: D000891:Anti-Infective Agents, Local; D015921:Dental Implants; D005782:Gels; D009067:Mouthwashes; D002710:Chlorhexidine