title: Sleep-disordered breathing in Beckwith-Wiedemann syndrome: three patients.
abstract: Beckwith-Wiedemann syndrome is associated with craniofacial abnormalities that may predispose patients to sleep-related breathing disorders. There is limited literature on the polysomnography findings for children with this syndrome. Three patients with Beckwith-Wiedemann syndrome underwent polysomnography in our sleep lab and were found to have a variety of sleep-disordered breathing that ranged from obstructive apnea to isolated REM sleep-related hypoxemia-hypoventilation without obstructive apnea. Suspicion for sleep-disordered breathing should be high in children with Beckwith-Wiedemann syndrome.
authors.affiliation: Department of Neurology, University of North Carolina at Chapel Hill, North Carolina 27599-7025, USA.
authors.forename: Sujay
authors.initials: S
authors.lastname: Kansagra
authors.forename: O'Neill
authors.initials: O
authors.lastname: D'Cruz
authors.forename: Terry L
authors.initials: TL
authors.lastname: Noah
authors.forename: Bradley V
authors.initials: BV
authors.lastname: Vaughn
mesh_terms: D001506:Beckwith-Wiedemann Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012891:Sleep Apnea Syndromes / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology