title: Perioperative risk factors for deep vein thrombosis after total hip arthroplasty or total knee arthroplasty.
abstract: OBJECTIVE
  To determine the perioperative frequency of deep vein thrombosis (DVT) after lower limb joint prosthesis surgery using Doppler ultrasonography (US).
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  Operating room and hospital ward.
  
  
  METHODS
  144 consecutive ASA physical status 1 and 2 patients who underwent elective total hip arthroplasty (THA; n=64) or total knee arthroplasty (TKA; n= 80).
  
  
  METHODS
  Patients were allocated to two groups, those who developed DVT (DVT group) postoperatively and those who did not (no-DVT group). To examine the perioperative risk factors for DVT after THA or TKA, comparative analysis of the two groups was done.
  
  
  METHODS
  Doppler US was performed on all patients from the bilateral femoral to lower limb to detect the existence of DVT postoperatively.
  
  
  RESULTS
  DVT was detected in 61 patients (42%), including three proximal DVT patients (2%). Preoperative elevated plasma D-dimer value [P = 0.0131, odds ratio (OR) 1.54, 95% CI 1.10-2.17] and history of hyperlipidemia (P = 0.0453, OR 6.92, 95% CI 1.04-46.00] were significant risk factors for the onset of DVT. A preoperative plasma D-dimer cutoff value as a diagnostic test was obtained as 0.85 μg/mL.
  
  
  CONCLUSIONS
  A high preoperative plasma D-dimer value and/or history of hyperlipidemia were risk factors for DVT after THA or TKA.
authors.affiliation: Department of Anesthesiology, Osaka Medical College, Takatsuki, Osaka 569-8686, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Shimoyama
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Sawai
authors.forename: Shinichi
authors.initials: S
authors.lastname: Tatsumi
authors.forename: Junko
authors.initials: J
authors.lastname: Nakahira
authors.forename: Masayuki
authors.initials: M
authors.lastname: Oka
authors.forename: Mikio
authors.initials: M
authors.lastname: Nakajima
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Jotoku
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Minami
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects* / Q000379:methods; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects* / Q000379:methods; D015331:Cohort Studies; D017558:Elective Surgical Procedures; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D018608:Ultrasonography, Doppler; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D