title: Cutaneous hypersensitivity to gluten.
abstract: We enrolled 14 female patients (aged 12-60 years) affected by celiac disease (confirmed by duodenal biopsy), presenting dermatologic eczematous lesions involving their face, neck, and overall arms, after application of gluten-containing emollient cream, bath, or face powder, or after contact with foods containing wheat and durum wheat. Five patients resulted positive to patch-by-patch with wheat and durum wheat (mild to moderate positivity) with erythema and vesicles, in correspondence of their sites of application. Utilizing gluten-free cream and bath, and wearing gloves before hand contact with food-containing wheat, in their common life, these patients showed an improvement of their cutaneous lesions and no relapses of dermatitis for a 6-month follow-up period.
authors.affiliation: U.O.C. Dermatology, NESMOS Department, Faculty of Medicine and Psychology, Sapienza University, Rome, Italy.
authors.forename: Antonella
authors.initials: A
authors.lastname: Tammaro
authors.forename: Alessandra
authors.initials: A
authors.lastname: Narcisi
authors.forename: Gabriella
authors.initials: G
authors.lastname: De Marco
authors.forename: Severino
authors.initials: S
authors.lastname: Persechino
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D002446:Celiac Disease / Q000150:complications / Q000276:immunology*; D002648:Child; D003358:Cosmetics / Q000009:adverse effects; D017453:Dermatitis, Irritant / Q000150:complications / Q000209:etiology* / Q000473:pathology; D005260:Female; D005502:Food / Q000009:adverse effects; D005983:Glutens / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D063465:Skin Cream / Q000009:adverse effects; D014908:Triticum / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D003358:Cosmetics; D005983:Glutens