title: Granulomatous variant of pigmented purpuric dermatosis.
abstract: Granulomatous pigmented purpuric dermatosis is a rare entity. Historically, it has been seen in Asians. In this article, we report the case of a white man with this unusual variant. A 65-year-old, white man presented with a 1-year history of asymptomatic purpuric to brown papules on both lower legs and more confluent on dorsum of feet. He had an underlying history of hypertension and hyperlipidemia. Skin biopsy revealed a granulomatous lympho-histocytary inflammatory infiltrate in papillary dermis and superficial reticular dermis with extravasation of red blood cells and siderophages. Periodic acid schiff (PAS), Giemsa and Ziehl-Neelsen stains were negative. A diagnosis of granulomatous pigmented purpuric dermatosis was made. From the 10 cases reported of this granulomatous variant, 6 were associated with hyperlipidemia. We report an additional case with this association.
authors.affiliation: Department of Dermatology, Hospital de Móstoles, Madrid, Spain. berta.perez@ono.com
authors.forename: Berta Pérez
authors.initials: BP
authors.lastname: Tato
authors.forename: Silvia
authors.initials: S
authors.lastname: Marinero Escobedo
authors.forename: Yosmar Carolina
authors.initials: YC
authors.lastname: Pérez González
authors.forename: Begoña
authors.initials: B
authors.lastname: Sánchez Albisua
authors.forename: Isabel
authors.initials: I
authors.lastname: Polimón Olabarrieta
authors.forename: Beatriz
authors.initials: B
authors.lastname: Encabo Mayoral
authors.forename: Paloma Fernández
authors.initials: PF
authors.lastname: López
mesh_terms: D000368:Aged; D001706:Biopsy; D006099:Granuloma / Q000209:etiology / Q000473:pathology*; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications; D008297:Male; D010859:Pigmentation Disorders / Q000209:etiology / Q000473:pathology*; D011693:Purpura / Q000209:etiology / Q000473:pathology*; D012867:Skin / Q000473:pathology*