title: [Thrombotic microangiopathy with anti-ADAMTS 13 antibodies revealing an acute Q fever].
abstract: BACKGROUND
  Q fever can commonly mimic systemic diseases, leading to several immunological manifestations. Thrombotic micro-angiopathies manifest as a spectrum of related disorders in the form of thrombocytopenic purpura and hemolytic uremic syndrome.
  
  
  METHODS
  We report a 77-year-old woman, who presented an acquired thrombotic microangiopathy with renal expression associated with the presence of anti-ADAMTS 13 antibodies, which occurred during an acute infection by Coxiella burnetii (acute Q fever).
  
  
  CONCLUSIONS
  Auto-immune disorders are well-known in chronic or acute Q fever but to our knowledge, this is the first reported observation of thrombotic microangiopathy with anti-ADAMTS 13 antibodies.
authors.affiliation: Clinique de médecine interne, hôpital Michallon, CHU de Grenoble, BP 217, 38043 Grenoble cedex 09, France. NMorel1@chu-grenoble.fr
authors.forename: N
authors.initials: N
authors.lastname: Morel
authors.forename: E
authors.initials: E
authors.lastname: Berthoux
authors.forename: B
authors.initials: B
authors.lastname: Colombe
authors.forename: A
authors.initials: A
authors.lastname: Bosseray
authors.forename: C
authors.initials: C
authors.lastname: Massot
mesh_terms: D051722:ADAM Proteins / Q000276:immunology*; D000071120:ADAMTS13 Protein; D000368:Aged; D001323:Autoantibodies / Q000097:blood*; D005260:Female; D006801:Humans; D011778:Q Fever / Q000097:blood / Q000150:complications* / Q000175:diagnosis*; D057049:Thrombotic Microangiopathies / Q000097:blood / Q000209:etiology* / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D051722:ADAM Proteins; D000071120:ADAMTS13 Protein; C099604:ADAMTS13 protein, human