title: Single-shot quantitative dispersion phase microscopy.
abstract: We present an imaging modality capable of providing high-speed optical dispersion measurements of live cells. The technique permits wide-field measurement of the optical phase shifts introduced by a sample for multiple discrete wavelengths in a single image capture. Utilizing spatial modulation and the wavelength dependence of the interference-fringe spacing, average refractive index as a function of wavelength is obtained, yielding optical dispersion measurements of the sample under observation. Because of its simple and low-cost design, the technique can be readily integrated into a standard microscope to collect additional diagnostic information about biological cells.
authors.affiliation: George R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.
authors.forename: Niyom
authors.initials: N
authors.lastname: Lue
authors.forename: Jeon Woong
authors.initials: JW
authors.lastname: Kang
authors.forename: Timothy R
authors.initials: TR
authors.lastname: Hillman
authors.forename: Ramachandra R
authors.initials: RR
authors.lastname: Dasari
authors.forename: Zahid
authors.initials: Z
authors.lastname: Yaqoob