title: Divergent synthesis of benzene derivatives: Brønsted acid catalyzed and iodine-promoted tandem cyclization of 5,2-enyn-1-ones.
abstract: Highly substituted benzene derivatives, including alkoxy-, iodoalkoxy-, and diiodo-substituted benzenes, can be selectively synthesized via Brønsted acid catalyzed and iodine-promoted tandem carbocyclization respectively. This reaction involved a direct process for C-C bond formation from 5,2-enyn-1-ones, and different reaction systems (Brønsted acids/electrophiles with solvents) afforded different substituted benzenes. Furthermore, the halogenated moiety and alkoxy group can be readily introduced into the benzene in a position which has not been easily obtained previously.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, People's Republic of China.
authors.forename: Fang
authors.initials: F
authors.lastname: Yang
authors.forename: Yi-Feng
authors.initials: YF
authors.lastname: Qiu
authors.forename: Ke-Gong
authors.initials: KG
authors.lastname: Ji
authors.forename: Yan-Ning
authors.initials: YN
authors.lastname: Niu
authors.forename: Shaukat
authors.initials: S
authors.lastname: Ali
authors.forename: Yong-Min
authors.initials: YM
authors.lastname: Liang
mesh_terms: D000143:Acids / Q000737:chemistry*; D000475:Alkenes / Q000737:chemistry*; D000480:Alkynes / Q000737:chemistry*; D001554:Benzene / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D007455:Iodine / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000143:Acids; D000475:Alkenes; D000480:Alkynes; D007659:Ketones; D007455:Iodine; D001554:Benzene