title: Rapid detection of Staphylococcus aureus in lower respiratory tract secretions from patients with suspected ventilator-associated pneumonia: evaluation of the Cepheid Xpert MRSA/SA SSTI assay.
abstract: A preclinical evaluation was conducted to evaluate the performance of the Cepheid Xpert assay on 135 lower respiratory tract secretions for detection of methicillin-resistant Staphylococcus aureus and S. aureus. Compared with the quantitative culture, the sensitivity, specificity, and positive and negative predictive values were 99.0%, 72.2%, 90.7%, and 96.3%, respectively.
authors.affiliation: Servicio de Microbiología y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Madrid, Spain. ecercenado@terra.es
authors.forename: Emilia
authors.initials: E
authors.lastname: Cercenado
authors.forename: Mercedes
authors.initials: M
authors.lastname: Marín
authors.forename: Almudena
authors.initials: A
authors.lastname: Burillo
authors.forename: Pablo
authors.initials: P
authors.lastname: Martín-Rabadán
authors.forename: Marisa
authors.initials: M
authors.lastname: Rivera
authors.forename: Emilio
authors.initials: E
authors.lastname: Bouza
mesh_terms: D001431:Bacteriological Techniques / Q000379:methods*; D012634:Bodily Secretions / Q000382:microbiology*; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D011023:Pneumonia, Staphylococcal / Q000175:diagnosis* / Q000382:microbiology; D053717:Pneumonia, Ventilator-Associated / Q000175:diagnosis* / Q000382:microbiology; D011237:Predictive Value of Tests; D012137:Respiratory System / Q000382:microbiology*; D012680:Sensitivity and Specificity; D013211:Staphylococcus aureus / Q000302:isolation & purification*