title: [Long-term survival of a patient with giant liver metastatic breast cancer treated with trastuzumab].
abstract: We report the long-term survival of a patient with metastatic breast cancer treated with trastuzumab and chemoendocrine therapy. The patient was a 60-year-old female. She underwent right mastectomy with axillary lymphadenectomy I c for advanced right breast cancer in 1999. In 2007, she consulted our hospital for treatment of recurrent giant liver metastasis. A giant liver metastasis up to 15 cm in diameter was detected by CT upon arrival. After 4 years of trastuzumab and chemoendocrine therapy, she was diagnosed as in progressive remission with good quality of life. Breast cancer with liver metastasis often can be life-threatening. Therefore, an optimal chemotherapy should be applied as soon as possible. Trastuzumab and chemoendocrine therapy showed efficacy for the treatment of a HER2-positive breast cancer with recurrent giant liver metastasis.
authors.affiliation: Dept. of Surgery, Teine Keijinkai Hospital.
authors.forename: Naoya
authors.initials: N
authors.lastname: Okada
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Narita
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Nanno
authors.forename: Mayu
authors.initials: M
authors.lastname: Shimaguchi
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Imamura
authors.forename: Rei
authors.initials: R
authors.lastname: Inoue
authors.forename: Toru
authors.initials: T
authors.lastname: Nakamura
authors.forename: Minoru
authors.initials: M
authors.lastname: Takada
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Kato
authors.forename: On
authors.initials: O
authors.lastname: Suzuki
authors.forename: Yoshiyasu
authors.initials: Y
authors.lastname: Ambo
authors.forename: Fumitaka
authors.initials: F
authors.lastname: Nakamura
authors.forename: Akihiro
authors.initials: A
authors.lastname: Kishida
authors.forename: Nobuichi
authors.initials: N
authors.lastname: Kashimura
authors.forename: Osamu
authors.initials: O
authors.lastname: Matsunami
mesh_terms: D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D018450:Disease Progression; D005260:Female; D020249:Hormone Replacement Therapy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008875:Middle Aged; D012008:Recurrence; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D000068878:Trastuzumab
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D000068878:Trastuzumab