title: Structural characterization and antimicrobial properties of silver nanoparticles prepared by inverse microemulsion method.
abstract: Silver nanoparticles have been synthesized in the inverse microemulsions formed using three different surfactants viz., cetyl-trimethyl ammonium bromide (CTAB), Tergitol and Triton X-100. We have done a systematic study of the effect of the surfactants on the particle size and properties of the silver nanoparticles. Microscopic studies show the formation of spheres, cubes and discs shaped silver nanostructures with the size in the range from 8 to 40 nm. Surface plasmon resonance (SPR) peak was observed around 400 nm and 500 nm. In addition to SPR some extra peaks have also been observed due to the formation of silver metal clusters. The surface area increases from 3.45 to 15.06 m(2)/g with decreasing the size of silver nanoparticles (40-8 nm). To investigate the antimicrobial activity of silver nanoparticles, the nanoparticles were tested against the yeast, Candida albicans and the bacterium, E. coli. The results suggest very good antimicrobial activity of the silver nanoparticles against the test microbes. The mode of action of the antimicrobial activity was also proposed.
authors.affiliation: Nanochemistry Laboratory, Department of Chemistry, Jamia Millia Islamia, New Delhi 110025, India.
authors.forename: Irshad A
authors.initials: IA
authors.lastname: Wani
authors.forename: Sarvari
authors.initials: S
authors.lastname: Khatoon
authors.forename: Aparna
authors.initials: A
authors.lastname: Ganguly
authors.forename: Jahangeer
authors.initials: J
authors.lastname: Ahmed
authors.forename: Tokeer
authors.initials: T
authors.lastname: Ahmad
authors.forename: Nikhat
authors.initials: N
authors.lastname: Manzoor
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects / Q000254:growth & development; D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry; D004655:Emulsions; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development; D008826:Microbial Sensitivity Tests; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles / Q000737:chemistry*; D017830:Octoxynol / Q000737:chemistry; D010316:Particle Size; D011060:Poloxalene / Q000737:chemistry; D012834:Silver / Q000737:chemistry* / Q000494:pharmacology*; D013056:Spectrophotometry, Ultraviolet; D020349:Surface Plasmon Resonance; D013501:Surface-Active Agents / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D000890:Anti-Infective Agents; D002593:Cetrimonium Compounds; D004655:Emulsions; D013501:Surface-Active Agents; D012834:Silver; D017830:Octoxynol; D011060:Poloxalene; D000077286:Cetrimonium