title: Uncommon cause of chest pain in a renal transplantation patient with autosomal dominant polycystic kidney disease: a case report.
abstract: Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of end-stage renal disease (ESRD) and, because of its intrinsic systemic involvement, its treatment can be a medical and surgical challenge. This condition is often associated with the presence of hepatic cysts and their prevalence generally increases with age. Most patients remain asymptomatic, but some of these will develop complications associated with enlargement and infection of their cysts. Chest pain is a rare manifestation of these complications and, after exclusion of more common cardiovascular and pulmonary causes, should raise the suspicion of an infected hepatic cyst in these patients. We report the case of a 62-year-old male who underwent a kidney transplantation from a cadaveric donor in 1997 (etiology of the ESRD was ADPKD), and was admitted to the emergency department with complaints of chest pain radiating to both shoulders and the interscapular region. An echocardiogram was showed compression of the right atrium by a large liver cyst without associated ventricular dysfunction. Computer tomography-guided drainage of the cyst was performed and an Enterobacter aerogenes sensitive to carbamapenemes was isolated from respective cultures. The patient presented a favorable clinical outcome with prolonged administration of antibiotic therapy according to the antibiotic susceptibility testing. There was no need for surgical intervention.
authors.affiliation: Department of Nephrology, Hospitais da Universidade de Coimbra, Coimbra, Portugal. luis.arodrigues@hotmail.com
authors.forename: L
authors.initials: L
authors.lastname: Rodrigues
authors.forename: M
authors.initials: M
authors.lastname: Neves
authors.forename: S
authors.initials: S
authors.lastname: Machado
authors.forename: H
authors.initials: H
authors.lastname: Sá
authors.forename: F
authors.initials: F
authors.lastname: Macário
authors.forename: R
authors.initials: R
authors.lastname: Alves
authors.forename: A
authors.initials: A
authors.lastname: Mota
authors.forename: M
authors.initials: M
authors.lastname: Campos
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002637:Chest Pain / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D003560:Cysts / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D004322:Drainage; D021902:Enterobacter aerogenes / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality / Q000628:therapy; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008107:Liver Diseases / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D016891:Polycystic Kidney, Autosomal Dominant / Q000150:complications / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents