title: Diagnostic and therapeutic impact of SPECT/CT in patients with unspecific pain of the hand and wrist.
abstract: BACKGROUND
  Unspecific pain of the hand/wrist is a diagnostic challenge. Radiographs and planar bone scan are useful diagnostic tools in patients with unspecific wrist pain. Both modalities are deficient, either by not presenting metabolic disorders or due to inadequate anatomical resolution. Single photon emission computed tomography/computed tomography (SPECT/CT) claims to fuse both features.
  
  
  METHODS
  Fifty-one patients with persisting wrist pain were referred for evaluation by SPECT/CT. All patients received X-ray and early-phase/late-phase SPECT/CT imaging. SPECT/CT results were compared with X-ray alone and X-ray combined with planar bone scan. The therapeutic impact was evaluated in consensus with the referring hand surgeon.
  
  
  RESULTS
  A total of 48 lesions were detected on plain radiographs, 117 on planar bone scan, and 142 on SPECT/CT. SPECT/CT detected significantly more lesions than the other imaging modalities. In 30 out of 51 patients (61%), a positive concordance between the clinical diagnosis and SPECT/CT findings was found. In 19 out of 51 patients (37%), SPECT/CT findings had significant impact on consecutive therapy.
  
  
  CONCLUSIONS
  SPECT/CT showed higher lesion detection rates compared to standard X-rays and planar bone scan. Significant impact on patient management could be demonstrated. SPECT/CT might be added to the workup of such a specific patient population when standard imaging fails to detect the patient's main pathology.
authors.affiliation: Department of Radiology and Nuclear Medicine, Lucerne Cantonal Hospital, Lucerne, CH-6000, Switzerland. patrick.veit-haibach@usz.ch.
authors.forename: Florian S
authors.initials: FS
authors.lastname: Schleich
authors.forename: Maja
authors.initials: M
authors.lastname: Schürch
authors.forename: Martin W
authors.initials: MW
authors.lastname: Huellner
authors.forename: Urs
authors.initials: U
authors.lastname: Hug
authors.forename: Urs
authors.initials: U
authors.lastname: von Wartburg
authors.forename: Klaus
authors.initials: K
authors.lastname: Strobel
authors.forename: Patrick
authors.initials: P
authors.lastname: Veit-Haibach