title: Dorsolateral frontal lobe epilepsy.
abstract: Dorsolateral frontal lobe seizures often present as a diagnostic challenge. The diverse semiologies may not produce lateralizing or localizing signs and can appear bizarre and suggest psychogenic events. Unfortunately, scalp electroencephalographic (EEG) and magnetic resonance imaging (MRI) are often unsatisfactory. It is not uncommon that these traditional diagnostic studies are either unhelpful or even misleading. In some cases, SPECT and positron emission tomography imaging can be an effective tool to identify the origin of seizures. However, these techniques and other emerging techniques all have limitations, and new approaches are needed to improve source localization.
authors.affiliation: Department of Neurology, Division of Clinical Neurophysiology, Mayo Clinic, Rochester, MN, USA.
authors.forename: Ricky W
authors.initials: RW
authors.lastname: Lee
authors.forename: Greg A
authors.initials: GA
authors.lastname: Worrell
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D001931:Brain Mapping / Q000379:methods; D058256:Brain Waves / Q000187:drug effects; D004569:Electroencephalography; D017034:Epilepsy, Frontal Lobe / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D005260:Female; D005625:Frontal Lobe / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D019635:Neurosurgical Procedures; D010507:Periodicity; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D015899:Tomography, Emission-Computed, Single-Photon; D016896:Treatment Outcome
chemical_list: D000927:Anticonvulsants