title: Relaxin-3 is associated with metabolic syndrome and its component traits in women.
abstract: OBJECTIVE
  Relaxin-3 was found to play a role in appetite regulation, increasing food intake and body weight. The current study aimed to investigate the relation of relaxin-3 to metabolic syndrome and its component traits in women.
  
  
  METHODS
  The study was conducted on 300 female subjects, 150 healthy control and 150 metabolic syndrome patients. The component traits of metabolic syndrome were determined for all participants.
  
  
  RESULTS
  Serum relaxin-3 level was significantly higher in the metabolic syndrome patients than in the healthy control group. It was also significantly correlated with all the component traits of metabolic syndrome.
  
  
  CONCLUSIONS
  The results suggest that metabolic syndrome is associated with increased serum relaxin-3 levels in women. Relaxin-3 might be considered as a potential biomarker of metabolic syndrome.
authors.affiliation: Department of Medical Biochemistry, Faculty of Medicine, Suez Canal University, 41522 Ismailia, Egypt.
authors.forename: Maivel H
authors.initials: MH
authors.lastname: Ghattas
authors.forename: Eman T
authors.initials: ET
authors.lastname: Mehanna
authors.forename: Noha M
authors.initials: NM
authors.lastname: Mesbah
authors.forename: Dina M
authors.initials: DM
authors.lastname: Abo-Elmatty
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D015992:Body Mass Index; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D024821:Metabolic Syndrome / Q000097:blood* / Q000209:etiology*; D011237:Predictive Value of Tests; D012372:ROC Curve; D012065:Relaxin / Q000097:blood*
chemical_list: D001786:Blood Glucose; D008055:Lipids; C480238:RLN3 protein, human; D012065:Relaxin