title: Cutaneous intravascular anaplastic large T-cell lymphoma:  a case report and review of the literature.
abstract: Intravascular lymphoma (IVL) is a rare subtype of extranodal lymphoma. In the 2008 WHO classification of tumors of the hematopoietic and lymphoid tissues intravascular large B-cell lymphoma is included as a distinct entity. IVL of T-cell type is not included as a diagnostic category and is only mentioned in passing by Nakamura et al. as "a different entity" in their discussion of intravascular large B-cell lymphoma. T-cell IVL is rare, the majority of cases being of natural killer/T-cell phenotype. Exceptionally rare is primary cutaneous intravascular anaplastic large T-cell lymphoma. We present such a case in an otherwise well 39-year-old female having disease limited to the skin established after detailed staging investigations. This is only the third such case described in the literature. We report the clinicopathological features of this case and also review previously documented cases of cutaneous intravascular anaplastic large cell lymphoma.
authors.affiliation: Department of Anatomical Pathology, PathWest Laboratory Medicine, QEII Medical Centre, Perth, Western Australia, Australia.
authors.forename: Jean
authors.initials: J
authors.lastname: Iacobelli
authors.forename: Dominic V
authors.initials: DV
authors.lastname: Spagnolo
authors.forename: Yordanos
authors.initials: Y
authors.lastname: Tesfai
authors.forename: Tindaro M
authors.initials: TM
authors.lastname: Giardina
authors.forename: Jonathan J
authors.initials: JJ
authors.lastname: Chan
authors.forename: David
authors.initials: D
authors.lastname: Joske
authors.forename: Benjamin A
authors.initials: BA
authors.lastname: Wood
mesh_terms: D000328:Adult; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000235:genetics; D007150:Immunohistochemistry; D016130:Immunophenotyping; D054446:Lymphoma, Primary Cutaneous Anaplastic Large Cell / Q000235:genetics / Q000473:pathology*; D012878:Skin Neoplasms / Q000235:genetics / Q000473:pathology*
chemical_list: D007145:Immunoglobulin kappa-Chains