title: [Study on HPLC characteristic fingerprint of active components of dachuanxiong fang in plasma and cerebrospinal fluid].
abstract: OBJECTIVE
  To establish an accurate and simple qualitative analytical method in vivo in the study on HPLC characteristic fingerprint of active components of dachuanxiong fang in plasma and cerebrospinal fluid, in order to lay a foundation for studies on components found in plasma and cerebrospinal fluid and provide basis for compatible regularity of initiators.
  
  
  METHODS
  HPLC characteristic fingerprint of active components of dachuanxiong fang in plasma and cerebrospinal fluid was established.
  
  
  RESULTS
  The similarity of fingerprints of all of six batches of samples was above 0.85, RSD of their relative retention times in common peaks was less than 2. 0%.
  
  
  CONCLUSIONS
  The fingerprints of active components of dachuanxiong fang in plasma and cerebrospinal fluid were stable and accurate that they can be used in qualitative analysis on in vivo components.
authors.affiliation: Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine of Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. alansusu@sina.com
authors.forename: Lan
authors.initials: L
authors.lastname: Shen
authors.forename: Xiao
authors.initials: X
authors.lastname: Lin
authors.forename: Yanlong
authors.initials: Y
authors.lastname: Hong
authors.forename: Shuang
authors.initials: S
authors.lastname: Liang
authors.forename: Ying
authors.initials: Y
authors.lastname: Yuan
authors.forename: Yi
authors.initials: Y
authors.lastname: Feng
authors.forename: Desheng
authors.initials: D
authors.lastname: Xu
authors.forename: Kefeng
authors.initials: K
authors.lastname: Ruan
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000032:analysis* / Q000378:metabolism; D008297:Male; D008516:Medicine, Chinese Traditional; D010936:Plant Extracts / Q000097:blood* / Q000134:cerebrospinal fluid*; D011786:Quality Control; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D004365:Drugs, Chinese Herbal; D010936:Plant Extracts