title: Hypopituitarism following poisonous viperbite.
abstract: A 28 years old male had the history of viperbite 3 years back. He has treated in a nearby rural hospital with snake venom antiserum along with other supportive therapy. He responded and discharged from hospital within a week. Three years later he had history of fever, drowsiness which progressed to unconsciousness. On examination he was found to have scanty body hairs, smooth, shiny skin with superficial oral ulcers. Serum hormone estimation confirmed the deficiency of gonadotrophins, thyrotrophin and corticotrophin while growth hormone failed to rise >3ng/ml after insulin intolerance test. MRI brain revealed loss of pituitary mass with positive infundibular sign and filling of sella with cerebrospinal fluid. He was managed with hormone replacement therapy and recovered gradually.
authors.affiliation: Department of Medicine, NRS Medical College, Kolkata 700014.
authors.forename: Sanjay Kumar
authors.initials: SK
authors.lastname: Bandyopadhyay
authors.forename: Ranjana
authors.initials: R
authors.lastname: Bandyopadhyay
authors.forename: Anita
authors.initials: A
authors.lastname: Dutta
authors.forename: Salil Kumar
authors.initials: SK
authors.lastname: Pal
mesh_terms: D000328:Adult; D000818:Animals; D020249:Hormone Replacement Therapy / Q000379:methods; D006801:Humans; D007018:Hypopituitarism / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D017840:Daboia; D012909:Snake Bites / Q000150:complications*; D013997:Time Factors