title: Propargyl Claisen rearrangement: allene synthesis and beyond.
abstract: The propargyl Claisen rearrangement is a known protocol to gain access to functionalized allenes through the [3,3]-sigmatropic transformation of propargyl vinyl ethers. The correct use of appropriate propargyl vinyl ethers as starting materials coupled with suitable reaction conditions can aid in the development of new domino methodologies in which the allenes are valuable intermediates in route to a wide range of important classes of organic compounds.
authors.affiliation: Instituto de Productos Naturales y Agrobiología, CSIC, Astrofísico Francisco Sánchez 3, 38206 La Laguna, Tenerife, Canary Islands, Spain. dtejedor@ipna.csic.es
authors.forename: David
authors.initials: D
authors.lastname: Tejedor
authors.forename: Gabriela
authors.initials: G
authors.lastname: Méndez-Abt
authors.forename: Leandro
authors.initials: L
authors.lastname: Cotos
authors.forename: Fernando
authors.initials: F
authors.lastname: García-Tellado
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis / Q000737:chemistry; D000466:Alkadienes / Q000138:chemical synthesis* / Q000737:chemistry; D000480:Alkynes / Q000138:chemical synthesis / Q000737:chemistry*; D000498:Allyl Compounds / Q000138:chemical synthesis / Q000737:chemistry; D004987:Ethers / Q000138:chemical synthesis / Q000737:chemistry*; D014753:Vinyl Compounds / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000438:Alcohols; D000466:Alkadienes; D000480:Alkynes; D000498:Allyl Compounds; D004987:Ethers; D014753:Vinyl Compounds; C531209:propargyl ether; C025947:propadiene