title: Antibiotic prophylaxis in urology departments, 2005-2010.
abstract: BACKGROUND
  Antibiotic prophylaxis (AP) is an important measure in preventing health care-associated urinary tract infections (HAUTIs). Despite regional variations in the bacterial spectrum and antibiotic susceptibility patterns, guideline recommendations are usually given on an international level.
  
  
  OBJECTIVE
  To describe the use of AP in urology departments and relate this to relevant parameters such as country, type of hospital, and European Association of Urology guideline recommendations.
  
  
  METHODS
  Data from the Global Prevalence Study on Infections in Urology for the period 2005-2010 were analysed to evaluate the use of antibiotics in general and AP for urologic procedures. Of the 13 723 patients enrolled, 8178 received antibiotics on the study days.
  
  
  METHODS
  Study data were imported from the Web-based survey into Microsoft Access and exported into SPSS v.17.0. The data were then coded and analysed. The Pearson chi-Square test was used to compare categorical data and a probability level of 5% was considered significant. Multiple logistic regression analysis was used to define significantly different variables in multiple set categories.
  
  
  CONCLUSIONS
  Questions on AP were answered on 8370 forms and 6306 (75.3%) investigators reported their routine application of AP. Routine AP was highest in Latin America (n=337; 84%), followed by Asia (n=1338; 86%), Africa (n=234; 85%), and Europe (n=4116; 67%). The antibiotics most frequently used for AP were second-generation cephalosporins, ciprofloxacin, cefotaxime, and amoxicillin plus beta-lactamase inhibitor.
  
  
  CONCLUSIONS
  There were significant differences between countries/regions and types of hospitals, both in using AP for clean procedures and in the types of antibiotics used. AP was not always consistent with recommended guidelines.
authors.affiliation: Department of Urology, Aarhus University Hospital Skejby, 8200 Aarhus N, Denmark. metecek@gmail.com
authors.forename: Mete
authors.initials: M
authors.lastname: Çek
authors.forename: Zafer
authors.initials: Z
authors.lastname: Tandoğdu
authors.forename: Kurt
authors.initials: K
authors.lastname: Naber
authors.forename: Peter
authors.initials: P
authors.lastname: Tenke
authors.forename: Florian
authors.initials: F
authors.lastname: Wagenlehner
authors.forename: Edgar
authors.initials: E
authors.lastname: van Oostrum
authors.forename: Brian
authors.initials: B
authors.lastname: Kristensen
authors.forename: Truls Erik
authors.initials: TE
authors.lastname: Bjerklund Johansen
mesh_terms: D000293:Adolescent; D000328:Adult; D000349:Africa / Q000453:epidemiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis / Q000706:statistics & numerical data*; D001208:Asia / Q000453:epidemiology; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control; D005060:Europe / Q000453:epidemiology; D005260:Female; D019983:Guideline Adherence / Q000706:statistics & numerical data; D006801:Humans; D007843:Latin America / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000453:epidemiology / Q000517:prevention & control*; D013520:Urologic Surgical Procedures / Q000379:methods / Q000706:statistics & numerical data; D014573:Urology Department, Hospital / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents