title: Synthetic multicellularity.
abstract: The ability to synthesize biological constructs on the scale of the organisms we observe unaided is probably one of the more outlandish, yet recurring, dreams humans have had since they began to modify genes. This review brings together recent developments in synthetic biology, cell and developmental biology, computation, and technological development to provide context and direction for the engineering of rudimentary, autonomous multicellular ensembles.
authors.affiliation: Department of Electrical Engineering and Computer Science, University of California, Berkeley, CA 94720, USA. maharbiz@eecs.berkeley.edu
authors.forename: Michel M
authors.initials: MM
authors.lastname: Maharbiz
mesh_terms: D054742:Acyl-Butyrolactones / Q000378:metabolism; D000818:Animals; D002448:Cell Adhesion; D002450:Cell Communication; D016764:Cell Polarity; D002477:Cells / Q000166:cytology* / Q000378:metabolism; D019295:Computational Biology / Q000379:methods; D015509:Developmental Biology / Q000379:methods; D005109:Extracellular Matrix / Q000378:metabolism*; D005818:Genetic Engineering / Q000379:methods*; D006801:Humans; D058615:Synthetic Biology / Q000379:methods*; D049490:Systems Biology
chemical_list: D054742:Acyl-Butyrolactones