title: Recurrent aseptic meningitis in association with Kikuchi-Fujimoto disease: case report and literature review.
abstract: BACKGROUND
  Kikuchi Fujimoto disease (KFD), or histiocytic necrotising lymphadenitis, is a benign and self-limiting condition characterised by primarily affecting the cervical lymph nodes. Recurrent aseptic meningitis in association with KFD is extremely rare and remains a diagnostic challenge.
  
  
  METHODS
  We report a 28-year-old man who presented 7 episodes of aseptic meningitis associated with KFD over the course of 7 years. Histopathological findings of enlarged lymph nodes led to the diagnosis of KFD. The patient's headache and lymphadenopathy spontaneously resolved without any sequelae.
  
  
  CONCLUSIONS
  A diagnosis of KFD should be considered when enlarged cervical lymph nodes are observed in patients with recurrent aseptic meningitis. A long-term prognosis remains uncertain, and careful follow-up is preferred.
authors.affiliation: Department of Neurology, Dokkyo Medical University, Shimotsuga, Tochigi, Japan. tkoma@dokkyomed.ac.jp
authors.forename: Tomoko
authors.initials: T
authors.lastname: Komagamine
authors.forename: Takahide
authors.initials: T
authors.lastname: Nagashima
authors.forename: Masaru
authors.initials: M
authors.lastname: Kojima
authors.forename: Norito
authors.initials: N
authors.lastname: Kokubun
authors.forename: Toshiki
authors.initials: T
authors.lastname: Nakamura
authors.forename: Kenich
authors.initials: K
authors.lastname: Hashimoto
authors.forename: Kazuhito
authors.initials: K
authors.lastname: Kimoto
authors.forename: Koichi
authors.initials: K
authors.lastname: Hirata
mesh_terms: D020042:Histiocytic Necrotizing Lymphadenitis / Q000150:complications* / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008582:Meningitis, Aseptic / Q000150:complications* / Q000473:pathology; D055815:Young Adult