title: [A case of malakoplakia of the urinary bladder].
abstract: This is a case report of a 65-year-old female with malakoplakia in the urinary bladder. An ultrasound scan showed many tumor-like polyp lesions, where a transurethral resection was performed. Since the lesions revealed gross papillary neoplasms, malignancy was suspected. However, histpathological examination showed an aggregation of many infiltrating histiocytes containing characteristic Michaelis-Gutmann bodies positively reactive with von Kossa staining, indicating a typical case of malakoplakia of the urinary bladder. Immunohistochemical study demonstrated that the cytoplasms of the histiocytes were focally positive for an anti-Escherichia coli antibody. One of the etiologies of malakoplakia is infection by Escherichia coli, which is supported by our data.
authors.affiliation: Department of Pathology and Cell Biology, School of Medicine, University of Occupational and Environmental Health, Japan.
authors.forename: Atsunori
authors.initials: A
authors.lastname: Nabeshima
authors.forename: Sohsuke
authors.initials: S
authors.lastname: Yamada
authors.forename: Guo
authors.initials: G
authors.lastname: Xin
authors.forename: Takashi
authors.initials: T
authors.lastname: Tasaki
authors.forename: Shohei
authors.initials: S
authors.lastname: Kitada
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Noguchi
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Sasaguri
mesh_terms: D000368:Aged; D000907:Antibodies, Bacterial / Q000032:analysis; D004926:Escherichia coli / Q000276:immunology; D004927:Escherichia coli Infections / Q000150:complications; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008287:Malacoplakia / Q000209:etiology / Q000473:pathology*; D001745:Urinary Bladder Diseases / Q000209:etiology / Q000473:pathology*
chemical_list: D000907:Antibodies, Bacterial