title: Novel strategies to control lipid metabolism: can the antisense drug mipomersen fulfill the unmet need?
authors.forename: Daniel
authors.initials: D
authors.lastname: Merk
authors.forename: Manfred
authors.initials: M
authors.lastname: Schubert-Zsilavecz
mesh_terms: D000924:Anticholesteremic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D053299:Apolipoprotein B-100 / Q000235:genetics; D001055:Apolipoproteins B / Q000235:genetics; D008078:Cholesterol, LDL / Q000097:blood / Q000378:metabolism; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism; D050356:Lipid Metabolism / Q000187:drug effects*; D020319:Oligodeoxyribonucleotides, Antisense / Q000009:adverse effects / Q000627:therapeutic use*; D009841:Oligonucleotides / Q000627:therapeutic use*; D012333:RNA, Messenger / Q000235:genetics
chemical_list: D000924:Anticholesteremic Agents; D053299:Apolipoprotein B-100; D001055:Apolipoproteins B; D008078:Cholesterol, LDL; D020319:Oligodeoxyribonucleotides, Antisense; D009841:Oligonucleotides; D012333:RNA, Messenger; C524142:mipomersen