title: Evolution: mitochondrial burden on male health.
abstract: In many animal species, males suffer more from age-related disease than females. Is there a common cause for this burden on male health? Recent work supports the theory that the female transmission of mitochondria disproportionately increases the mutation load in males.
authors.affiliation: Department of Ecology and Evolutionary Biology, University of California, Irvine, CA 92697, USA. safrank@uci.edu
authors.forename: Steven A
authors.initials: SA
authors.lastname: Frank
mesh_terms: D000818:Animals; D004272:DNA, Mitochondrial / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D054629:Genome, Mitochondrial; D008136:Longevity / Q000235:genetics*; D008297:Male; D008928:Mitochondria / Q000235:genetics*
chemical_list: D004272:DNA, Mitochondrial