title: Isolated Crohn's disease of the esophagus with esophago-mediastinal fistula formation.
abstract: Isolated Crohn's disease of the esophagus is rare, and accurate diagnosis and treatment in its early course are difficult. Most cases are often found very late, when severe strictures or other complications have occurred. We report the case of a male 60-year-old patient with complaints of progressive dysphagia for more than two months and the sudden appearance of heartburn for seven consecutive days. Clinical examination revealed severe esophageal stricture with a suspected fistula and mediastinitis. The patient received a successful esophagectomy. The resected specimen and pathological results confirmed a deep linear ulcer, chronic and noncaseating granulomatous inflammation, as well as a circular stricture of the esophagus with fistula into the mediastinum due to isolated esophageal Crohn's disease.
authors.affiliation: Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, PR China.
authors.forename: Wuping
authors.initials: W
authors.lastname: Wang
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Ni
authors.forename: Changkang
authors.initials: C
authors.lastname: Ke
authors.forename: Qingshu
authors.initials: Q
authors.lastname: Cheng
authors.forename: Qiang
authors.initials: Q
authors.lastname: Lu
authors.forename: Xiaofei
authors.initials: X
authors.lastname: Li
mesh_terms: D003424:Crohn Disease / Q000209:etiology / Q000473:pathology*; D004935:Esophageal Diseases / Q000150:complications / Q000473:pathology*; D004940:Esophageal Stenosis / Q000209:etiology / Q000473:pathology*; D005402:Fistula / Q000209:etiology / Q000473:pathology*; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000209:etiology / Q000473:pathology*; D008875:Middle Aged; D011379:Prognosis; D014057:Tomography, X-Ray Computed