title: Diffuse pontine astrocytoma with lipocytic differentiation.
abstract: A 7-year-old boy was treated with radiation and chemotherapy for a diffuse pontine glioma. At autopsy, 8 months after diagnosis, the tumor was a diffuse grade II fibrillary astrocytoma with prominent lipocytic differentiation. Literature review suggests that lipocytic differentiation in low-grade astrocytomas occurs in a variety of patient ages, anatomic sites, grades, and astrocytic subtypes. Although the majority of low-grade lipoastrocytomas have behaved benignly, this child's lipoastrocytoma was the underlying cause of death. This outcome suggests that the outcomes of low-grade lipoastrocytic tumors may be expected to be the same as the underlying tumor subtype.
authors.affiliation: Department of Pathology, Louisiana State University School of Medicine, New Orleans, LA  ; Children's Hospital, New Orleans, LA.
authors.forename: Randall
authors.initials: R
authors.lastname: Craver
authors.forename: Christopher
authors.initials: C
authors.lastname: Arcement
authors.forename: Tammuella
authors.initials: T
authors.lastname: Chrisentery Singleton