title: Nanoparticles and peptides: a fruitful liaison for biomimetic catalysis.
abstract: Inspired by nature: self-assembled peptide nanoparticles have been designed that accelerate ester hydrolysis (see picture; Cbz=carbobenzyloxy, NP=p-NO(2)-C(6) H(4)). The concerted interplay of the multivalent surface with the catalytically active peptide and the substrate at the same time combines several aspects decisive for the catalyst's efficiency, a property characteristic of enzymes.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Germany.
authors.forename: Maciej
authors.initials: M
authors.lastname: Stodulski
authors.forename: Tanja
authors.initials: T
authors.lastname: Gulder
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry* / Q000378:metabolism; D032701:Biomimetics; D002384:Catalysis; D004952:Esters / Q000737:chemistry* / Q000378:metabolism; D053768:Metal Nanoparticles / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry* / Q000378:metabolism; D012834:Silver / Q000737:chemistry
chemical_list: D004952:Esters; D010455:Peptides; D012834:Silver