title: Remitting seronegative symmetrical synovitis with pitting edema (RS3PE); a rare association with phyllodes tumour of breast.
abstract: Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a rare entity mainly found in elderly males. It is characterized by pitting edema mainly of dorsum of both hands giving a "boxing glove hand" appearance; rarely involving feet also, acute in onset, negative rheumatoid factor and a good response to low dose corticosteroid therapy. Clinically it almost resembles a case of polymyalgia rheumatica, late onset rheumatoid arthritis or other seronegative spondyloarthropathy.Though there are multiple underlying factors causing this rare entity but it has very close associations with many malignancies.So far its association with solid tumours and hematological malignancies has been reported. Phyllodes tumour of breast shows wide spectrum of activity from a benign condition to a locally aggressive and sometimes metastatic tumour.One fourth of the cases recur after definitive treatment.Our case represent an unusual association with recurrent phyllodes tumour of breast with RS3PE.
authors.affiliation: Dept. of Medicine, Medical College, 88 College Street, Kolkata 700073.
authors.forename: R N
authors.initials: RN
authors.lastname: Sarkar
authors.forename: Sibaji
authors.initials: S
authors.lastname: Phaujdar
authors.forename: Siwalik
authors.initials: S
authors.lastname: Banerjee
authors.forename: Sattik
authors.initials: S
authors.lastname: Siddhanta
authors.forename: Dibyendu
authors.initials: D
authors.lastname: De
authors.forename: Kuntal
authors.initials: K
authors.lastname: Bhattachary
authors.forename: Hare Krishna
authors.initials: HK
authors.lastname: Pal
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D004487:Edema / Q000209:etiology; D005260:Female; D005528:Foot; D006225:Hand; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000150:complications* / Q000188:drug therapy; D003557:Phyllodes Tumor / Q000150:complications* / Q000473:pathology / Q000601:surgery; D013585:Synovitis / Q000209:etiology