title: Synthesis of the pentacyclic skeleton of the indole alkaloid arboflorine.
abstract: An effective synthesis of the pentacyclic core of the unusual Kopsia alkaloid arboflorine is reported. The success of the synthetic route rested on the use of a borylative C-H functionalization reaction, a convergent Suzuki cross-coupling to a C(2) halogenated indole, and an unprecedented transannular dehydrogenative C-N bond forming reaction.
authors.affiliation: Department of Chemistry, University of California, Berkeley, California 94720, USA.
authors.forename: Raul A
authors.initials: RA
authors.lastname: Leal
authors.forename: Danial R
authors.initials: DR
authors.lastname: Beaudry
authors.forename: Saeed K
authors.initials: SK
authors.lastname: Alzghari
authors.forename: Richmond
authors.initials: R
authors.lastname: Sarpong
mesh_terms: D015394:Molecular Structure; D046948:Secologanin Tryptamine Alkaloids / Q000138:chemical synthesis*
chemical_list: D046948:Secologanin Tryptamine Alkaloids; C516136:arboflorine