title: Histological and genetic characterization of true hermaphroditism in Korean pigs.
abstract: True hermaphrodites are animals of equivocal sex in which both male and female gonads develop simultaneously in the same individual. The frequency of true hermaphroditism is relatively higher in pigs than in other domestic animals. Two Korean pigs were diagnosed with true hermaphroditism showing ovotestes, epididymides, a penis and uteri. The testicular tissues consisted of Sertoli cells that were devoid of spermatogenic cells and showed proliferation of interstitial cells. However, uteri looked normal and had well-developed endometrial glands. Samples showed the interpretation of 38, XX female karyotype and sex-determining region Y (SRY) gene expression was negative. These findings could be helpful to understand true porcine hermaphroditism for animal research as well as for the industry of Korean domestic animals.
authors.affiliation: Department of Animal Science and Biotechnology, College of Agriculture and Life Science, Chungnam National University, Daejeon, Korea.
authors.forename: Dong-Soo
authors.initials: DS
authors.lastname: Lee
authors.forename: Ji Hye
authors.initials: JH
authors.lastname: Lee
authors.forename: Jie Yeun
authors.initials: JY
authors.lastname: Park
authors.forename: Seung Jun
authors.initials: SJ
authors.lastname: Lee
authors.forename: Keun Jung
authors.initials: KJ
authors.lastname: Kim
authors.forename: Eun Young
authors.initials: EY
authors.lastname: Kim
authors.forename: Hwa-Young
authors.initials: HY
authors.lastname: Son
authors.forename: Sea Hwan
authors.initials: SH
authors.lastname: Sohn
authors.forename: Jae Suk
authors.initials: JS
authors.lastname: Woo
authors.forename: Min Kyu
authors.initials: MK
authors.lastname: Kim
mesh_terms: D000818:Animals; D005260:Female; D020022:Genetic Predisposition to Disease; D059785:Karyotype; D008297:Male; D050090:Ovotesticular Disorders of Sex Development / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D056910:Republic of Korea; D013552:Swine; D013553:Swine Diseases / Q000235:genetics / Q000473:pathology*