title: Heteroaromatic imidazo[1,2-a]pyridines synthesis from C-H/N-H oxidative cross-coupling/cyclization.
abstract: A novel silver-mediated highly selective C-H/N-H oxidative cross-coupling/cyclization between 2-aminopyridines and terminal alkynes has been demonstrated. This approach provided a simple way to construct heteroaromatic imidazo[1,2-a]pyridines. By using this protocol, the marketed drug zolimidine (antiulcer) could be synthesized easily.
authors.affiliation: College of Chemistry and Molecular Sciences, Wuhan University, 430072, PR China.
authors.forename: Chuan
authors.initials: C
authors.lastname: He
authors.forename: Jing
authors.initials: J
authors.lastname: Hao
authors.forename: Huan
authors.initials: H
authors.lastname: Xu
authors.forename: Yiping
authors.initials: Y
authors.lastname: Mo
authors.forename: Huiying
authors.initials: H
authors.lastname: Liu
authors.forename: Juanjuan
authors.initials: J
authors.lastname: Han
authors.forename: Aiwen
authors.initials: A
authors.lastname: Lei