title: [Plasmacytoïd dendritic cells acute leukemia: a case report].
abstract: We describe a case of a patient hospitalized in haematology unit for treatment to blastic plasmacytoid dendritic cell neoplasm. Apart skin lesions found at diagnosis in 83% of patients, few elements suggest the diagnosis. Cytology is not characteristic and no cytogenetic abnormality is specific to the LpDC, the karyotype shows generally at least three cytogenetic abnormalities. Definitive diagnosis rests to identification of a blastic population with immunophenotype CD4+ CD56+. This leukemia is chemosensitive but the relapse rate is important and the survival time is 16 months.
authors.affiliation: Fédération des laboratoires, Hôpital d'instruction des armées Percy, Clamart, France. aurorebousquet@yahoo.fr
authors.forename: Aurore
authors.initials: A
authors.lastname: Bousquet
authors.forename: Caroline
authors.initials: C
authors.lastname: Doutrelon
authors.forename: Johanna
authors.initials: J
authors.lastname: Konopacki
authors.forename: Anne
authors.initials: A
authors.lastname: Marfaing-Koka
authors.forename: Amandine
authors.initials: A
authors.lastname: Segot
authors.forename: Christophe
authors.initials: C
authors.lastname: Martinaud
authors.forename: Thierry
authors.initials: T
authors.lastname: Samson
authors.forename: Bertrand
authors.initials: B
authors.lastname: Souleau
authors.forename: Jean-Valère
authors.initials: JV
authors.lastname: Malfuson
authors.forename: Thierry
authors.initials: T
authors.lastname: De Revel
authors.forename: Vincent
authors.initials: V
authors.lastname: Foissaud
mesh_terms: D000208:Acute Disease; D000368:Aged; D001415:Back; D001854:Bone Marrow Cells / Q000473:pathology; D003713:Dendritic Cells / Q000473:pathology*; D005260:Female; D006801:Humans; D007938:Leukemia / Q000175:diagnosis* / Q000473:pathology*; D017254:Leukemic Infiltration / Q000175:diagnosis / Q000473:pathology; D012867:Skin / Q000473:pathology; D013909:Thorax