title: Bacterial skin colonization and infections in patients with atopic dermatitis.
abstract: Atopic Dermatitis is a chronic inflammatory skin disease that affects a large number of children and adults. The disease results from an interaction between genetic predisposition, host environment, skin barrier defects, and immunological factors. A major aggravating factor associated with Atopic Dermatitis is the presence of microorganisms on the patient's skin surface. Staphylococcus aureus and Streptococcus pyogenes, for instance, can exacerbate chronic skin inflammation. As a result, antimicrobials have often been prescribed to control the acute phase of the disease. However, increased bacterial resistance to antimicrobial agents has made it difficult for dermatologists to prescribe appropriate medication. In the presence of disseminated dermatitis with secondary infection, systemic antibiotics need to be prescribed; however, treatment should be individualized, in an attempt to find the most effective antibiotic with fewer side effects. Also, the medication should be used for as short as possible in order to minimize bacterial resistance.
authors.affiliation: Health Sciences Federal University of Porto Alegre, RS, Brazil. vpetry@hotmail.com
authors.forename: Vanessa
authors.initials: V
authors.lastname: Petry
authors.forename: Giancarlo Resende
authors.initials: GR
authors.lastname: Bessa
authors.forename: Claudia Schermann
authors.initials: CS
authors.lastname: Poziomczyck
authors.forename: Caio Fernando de
authors.initials: CF
authors.lastname: Oliveira
authors.forename: Magda Blessmann
authors.initials: MB
authors.lastname: Weber
authors.forename: Renan Rangel
authors.initials: RR
authors.lastname: Bonamigo
authors.forename: Pedro Alves
authors.initials: PA
authors.lastname: d'Azevedo
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D003876:Dermatitis, Atopic / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D013207:Staphylococcal Skin Infections / Q000188:drug therapy*; D013211:Staphylococcus aureus
chemical_list: D000900:Anti-Bacterial Agents