title: Getting under the skin of adverse drug reactions.
abstract: Cutaneous drug reactions are among the most commonly reported adverse drug reactions. Drugs prescribed by orthopedic surgeons, such as antibiotics, opiates, and nonsteroidal anti-inflammatory drugs, are common offenders. Cutaneous drug reactions can range from those that are common, mild nuisances to those that are rare, severe, and life-threatening. Medications should be considered part of a differential diagnosis for any dermatologic condition. It is important to recognize the different clinical features and common drugs that are related to each type of reaction. This review characterizes the different forms of cutaneous drug reactions and the clinical features, proposed mechanisms, and drugs frequently associated with each.
authors.affiliation: Department of Pharmacy Services, University of Kentucky HealthCare, Lexington, Kentucky 40536, USA. carolyn.hempel@uky.edu
authors.forename: Carolyn
authors.initials: C
authors.lastname: Hempel
authors.forename: Craig
authors.initials: C
authors.lastname: Martin
mesh_terms: D003875:Drug Eruptions / Q000175:diagnosis* / Q000209:etiology* / Q000517:prevention & control; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans