title: Asymmetric stem cell division: precision for robustness.
abstract: Asymmetric cell division (ACD) produces two daughter cells with distinct fates or characteristics. Many adult stem cells use ACD as a means of maintaining stem cell number and thus tissue homeostasis. Here, we review recent progress on ACD, discussing conservation between stem and non-stem cell systems, molecular mechanisms, and the biological meaning of ACD.
authors.affiliation: Life Sciences Institute, Center for Stem Cell Biology, University of Michigan, Ann Arbor, MI 48109, USA.
authors.forename: Mayu
authors.initials: M
authors.lastname: Inaba
authors.forename: Yukiko M
authors.initials: YM
authors.lastname: Yamashita
mesh_terms: D053687:Adult Stem Cells / Q000502:physiology*; D000818:Animals; D060049:Asymmetric Cell Division; D002450:Cell Communication; D016764:Cell Polarity; D006706:Homeostasis; D006801:Humans; D059566:M Phase Cell Cycle Checkpoints