title: The social brain in psychiatric and neurological disorders.
abstract: Psychiatric and neurological disorders have historically provided key insights into the structure-function relationships that subserve human social cognition and behavior, informing the concept of the 'social brain'. In this review, we take stock of the current status of this concept, retaining a focus on disorders that impact social behavior. We discuss how the social brain, social cognition, and social behavior are interdependent, and emphasize the important role of development and compensation. We suggest that the social brain, and its dysfunction and recovery, must be understood not in terms of specific structures, but rather in terms of their interaction in large-scale networks.
authors.affiliation: California Institute of Technology, 1200 E. California Blvd, HSS 228-77, Caltech, Pasadena, CA 91125, USA. dpk@indiana.edu
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Kennedy
authors.forename: Ralph
authors.initials: R
authors.lastname: Adolphs
mesh_terms: D061085:Agenesis of Corpus Callosum / Q000503:physiopathology; D000679:Amygdala / Q000503:physiopathology; D001921:Brain / Q000503:physiopathology*; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000209:etiology / Q000503:physiopathology; D003072:Cognition Disorders / Q000503:physiopathology*; D006801:Humans; D009422:Nervous System Diseases / Q000503:physiopathology*; D059906:Neuroimaging; D012919:Social Behavior; D012938:Social Perception; D018980:Williams Syndrome / Q000209:etiology / Q000503:physiopathology