title: Salivary diagnostics for periodontal diseases.
abstract: BACKGROUND
  and Overview The use of salivary diagnostics continues to develop and advance the field of risk determination for periodontal diseases. Researchers are investigating genetic, microbial and protein biomarkers with the objective of translating findings to such aspects of clinical care as broad patient screening, monitoring and treatment planning.
  
  
  METHODS
  /st> In this review, the author briefly explores currently available salivary diagnostics used to identify bacteria prevalent in periodontal disease, and focuses on the future development and use of a variety of rapid disease detection platforms, such as lab-on-a-chip, as a point-of-care device for identification of patients' risk.
  
  
  CONCLUSIONS
  and
  
  
  CONCLUSIONS
  /st> Several diagnostic tests are commercially available, and point-of-care tests are under development. However, challenges remain regarding the introduction of these technologies to clinical practice and adoption by dental practitioners for promotion of personalized oral health care.
authors.affiliation: Department of Periodontics and Oral Medicine, Michigan Center for Oral Health Research, School of Dentistry, University of Michigan, 1011 N University Ave, Ann Arbor, Mic 48109-1078, USA. william.giannobile@umich.edu
authors.forename: William V
authors.initials: WV
authors.lastname: Giannobile
mesh_terms: D001419:Bacteria / Q000145:classification; D015415:Biomarkers / Q000032:analysis; D054884:Host-Pathogen Interactions; D006801:Humans; D056656:Lab-On-A-Chip Devices; D010510:Periodontal Diseases / Q000175:diagnosis* / Q000382:microbiology; D019095:Point-of-Care Systems; D057285:Precision Medicine / Q000379:methods; D018570:Risk Assessment; D012463:Saliva / Q000737:chemistry* / Q000382:microbiology
chemical_list: D015415:Biomarkers