title: [A case of primary biliary cirrhosis with systemic lymph node enlargement].
abstract: A 40's woman was hospitalized with cervical lymph node enlargement. Laboratory examinations showed elevated serum bile duct enzymes and the presence of anti-mitochondrial antibody. Abdominal ultrasonography and computed tomography showed enlargement of not only perihepatic lymph nodes, but also axillary and cervical lymph nodes. FDG-PET showed intense uptake concordant with these lymph nodes. We performed endoscopic ultrasonographic fine-needle aspiration biopsy of a perihepatic lymph node, but detected no malignant cells. We then performed liver biopsy, and obtained a histological diagnosed primary biliary cirrhosis. Systemic lymph nodes decreased together with serum bile duct enzyme levels during treatment with ursodeoxycholic acid.
authors.affiliation: Department of Gastroenterology, Osaka City General Hospital, Japan. s-hiramatsu@hospital.city.osaka.jp
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Hiramatsu
authors.forename: Hiroko
authors.initials: H
authors.lastname: Nebiki
authors.forename: Ayako
authors.initials: A
authors.lastname: Ueno
authors.forename: Hirotsugu
authors.initials: H
authors.lastname: Maruyama
authors.forename: Takehisa
authors.initials: T
authors.lastname: Suekane
authors.forename: Tomoaki
authors.initials: T
authors.lastname: Yamasaki
authors.forename: Eiji
authors.initials: E
authors.lastname: Sasaki
authors.forename: Koji
authors.initials: K
authors.lastname: Sano
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sato
authors.forename: Takashi
authors.initials: T
authors.lastname: Nakai
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Kawasaki
authors.forename: Kiyohide
authors.initials: K
authors.lastname: Kioka
mesh_terms: D000328:Adult; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis* / Q000473:pathology; D008198:Lymph Nodes / Q000473:pathology*; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed