title: Psychiatric pharmacogenomics in pediatric psychopharmacology.
abstract: This article provides an overview of where psychiatric pharmacogenomic testing stands as an emerging clinical tool in modern psychotropic prescribing practice, specifically in the pediatric population. This practical discussion is organized around the state of psychiatric pharmacogenomics research when choosing psychopharmacologic interventions in the most commonly encountered mental illnesses in youth. As with the rest of the topics on psychopharmacology for children and adolescents in this publication, a clinical vignette is presented, this one highlighting a clinical case of a 16 year old genotyped during hospitalization for recalcitrant depression.
authors.affiliation: Division of Child and Adolescent Psychiatry, Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN 55905, USA. wall.chris@mayo.edu
authors.forename: Christopher A
authors.initials: CA
authors.lastname: Wall
authors.forename: Paul E
authors.initials: PE
authors.lastname: Croarkin
authors.forename: Cosima
authors.initials: C
authors.lastname: Swintak
authors.forename: Brett A
authors.initials: BA
authors.lastname: Koplin
mesh_terms: D000293:Adolescent; D002648:Child; D003577:Cytochrome P-450 Enzyme System / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism; D010597:Pharmacogenetics; D011600:Psychopharmacology; D011619:Psychotropic Drugs / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D011954:Receptors, Dopamine / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D011985:Receptors, Serotonin / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism
chemical_list: D011619:Psychotropic Drugs; D011954:Receptors, Dopamine; D011985:Receptors, Serotonin; D003577:Cytochrome P-450 Enzyme System