title: Rosai-Dorfman disease with spontaneous resolution: case report of a child.
abstract: Rosai-Dorfman disease is a self-limiting condition caused by histiocyte proliferation within the sinusoids of lymph nodes and in extranodal tissue. It is a rare disease, particularly in children, that progresses with extensive lymphadenopathy. This paper reports on the case of a 2-year-old child with progressive cervical lymphadenopathy associated with persistent fever and radiological findings suggestive of lymphoma. Histopathological and immunohistochemistry studies of a lymph node biopsy established the diagnosis of Rosai-Dorfman disease. Both lymphadenopathy and fever resolved spontaneously.
authors.affiliation: Universidade Federal do Ceará - UFC, Fortaleza, CE, Brazil.
authors.forename: Felipe Barbosa
authors.initials: FB
authors.lastname: Lima
authors.forename: Pedro Samuel de Valões
authors.initials: PS
authors.lastname: Barcelos
authors.forename: Ana Paula Nunes
authors.initials: AP
authors.lastname: Constâncio
authors.forename: Cleto Dantas
authors.initials: CD
authors.lastname: Nogueira
authors.forename: Antônio Aldo
authors.initials: AA
authors.lastname: Melo-Filho