title: Connecting membrane traffic to ESCRT and the final cut.
abstract: The ESCRT (endosomal sorting complex required for transport) machinery is responsible for scission of the cytokinetic bridge that connects daughter cells at the end of mitosis. Specific endosomes are now found to mediate local bridge constriction and actin clearance in human cells, which contribute to the recruitment of ESCRT components at the abscission site.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Echard
mesh_terms: D008841:Actin Cytoskeleton; D001692:Biological Transport / Q000502:physiology; D002462:Cell Membrane / Q000502:physiology; D056827:Endosomal Sorting Complexes Required for Transport / Q000502:physiology*; D006801:Humans; D008938:Mitosis
chemical_list: D056827:Endosomal Sorting Complexes Required for Transport