title: N-heterocyclic carbene-palladium(II)-1-methylimidazole complex catalyzed amination between aryl chlorides and amides.
abstract: We report herein that amides are excellent N-sources in the NHC-Pd(II)-Im complex 1 catalyzed amination of aryl chlorides. In the presence of KO(t)Bu, various aryl chlorides and amides can react smoothly to give the corresponding aminated products in moderate to almost quantitative yields at room temperature within 6 h.
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University, Chashan University Town, Wenzhou, Zhejiang Province 325035, People's Republic of China.
authors.forename: Wen-Xin
authors.initials: WX
authors.lastname: Chen
authors.forename: Li-Xiong
authors.initials: LX
authors.lastname: Shao
mesh_terms: D000577:Amides / Q000737:chemistry*; D000586:Amination; D000814:Aniline Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry
chemical_list: D000577:Amides; D000814:Aniline Compounds; D006571:Heterocyclic Compounds; D006843:Hydrocarbons, Chlorinated; D007093:Imidazoles; D009942:Organometallic Compounds; C030011:carbene; D010165:Palladium; D008697:Methane; C018100:1-methylimidazole