title: In vivo models for male reproductive toxicology.
abstract: In Vivo Models for Male Reproductive Toxicology (Rochelle W. Tyl, Research Triangle Institute, Research Triangle Park, North Carolina). Assessment of male reproductive function requires a specific set of evaluations of the various steps in successful mating from sperm production to copulation to fertilization to production of a viable litter. This unit outlines the measurements that are standard for determining the effects of treatment with toxicant on the reproductive capacity of male mice and rats.
authors.affiliation: Center of Life Sciences and Toxicology Research Triangle Institute, Research Triangle Park, NC, USA.
authors.forename: Rochelle W
authors.initials: RW
authors.lastname: Tyl
mesh_terms: D000818:Animals; D005260:Female; D005837:Genitalia, Male / Q000187:drug effects*; D006801:Humans; D008297:Male; D051379:Mice; D008954:Models, Biological; D051381:Rats; D013094:Spermatozoa / Q000187:drug effects*; D018675:Toxicity Tests