title: Erdheim-Chester disease detected with 99mTc MDP bone SPECT/CT.
abstract: Erdheim-Chester disease (ECD) is a rare non-Langerhans' cell histiocytosis. Mild but permanent juxta-articular bone pain in mainly knees and ankles is the most frequent associated symptom. Despite the pathognomonic radiographic findings, most cases are still diagnosed by the pathologist.The lesions consist of lipid-storing CD 68 +/CD 1a--non-Langerhans' cell histiocytes, most frequently localized in bone but also involving multiple organ systems in the body. We present a case report in which the diagnosis of ECD was established with 99mTc MDP bone SPECT/CT.
authors.affiliation: Department of Nuclear Medicine, UZ Brussel, Brussels, Belgium.
authors.forename: G
authors.initials: G
authors.lastname: Ceulemans
authors.forename: M
authors.initials: M
authors.lastname: Keyaerts
authors.forename: L
authors.initials: L
authors.lastname: Verbruggen
authors.forename: A
authors.initials: A
authors.lastname: Hoorens
authors.forename: C
authors.initials: C
authors.lastname: Boulet
authors.forename: D
authors.initials: D
authors.lastname: Verdries
authors.forename: M
authors.initials: M
authors.lastname: De Maeseneer
authors.forename: B
authors.initials: B
authors.lastname: Ilsen
authors.forename: H
authors.initials: H
authors.lastname: Everaert
mesh_terms: D001706:Biopsy; D001842:Bone and Bones / Q000000981:diagnostic imaging* / Q000473:pathology; D003287:Contrast Media; D003937:Diagnosis, Differential; D031249:Erdheim-Chester Disease / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D005682:Gadolinium; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged; D011859:Radiography; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
chemical_list: D003287:Contrast Media; D019275:Radiopharmaceuticals; D005682:Gadolinium; D013669:Technetium Tc 99m Medronate