title: Preparation and characterization of fluorinated porcine hydroxyapatite.
abstract: Simple chemical and thermal treatments were applied to prepare fluorinated porcine hydroxyapatite (FPHA). Morphology of FPHA was observed using SEM. Physiochemical characteristics, namely crystalline phase, chemical composition, functional groups, and binding energy of fluorine were investigated using XRD, EDX, FTIR, and XPS respectively. Concentration of free fluoride ion released from FPHA in HCl solution (pH 3.0-4.0) was detected using a fluoride ion concentration meter. SEM, XPS, XRD, and FTIR results confirmed the fluorination of porcine hydroxyapatite (PHA). Significant crystal morphological difference was observed between PHA and FPHA. Concentration of free fluoride ion released from FPHA increased with rising concentration of immersion solution and length of immersion period. Fluoride was successfully incorporated into PHA by chemical and thermal processes in this study. Fluoride incorporation rate into PHA was a strong function of the fluorine concentration in the immersion solution.
authors.affiliation: Guanghua School of Stomatology, Hospital of Stomatology, Institute of Stomatological Research, Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, 56 Ling Yuan Road West, Guangzhou, China.
authors.forename: Quan
authors.initials: Q
authors.lastname: Liu
authors.forename: Zetao
authors.initials: Z
authors.lastname: Chen
authors.forename: Haijing
authors.initials: H
authors.lastname: Gu
authors.forename: Zhuofan
authors.initials: Z
authors.lastname: Chen
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000737:chemistry; D003461:Crystallography; D017886:Durapatite / Q000138:chemical synthesis* / Q000737:chemistry; D005459:Fluorides / Q000032:analysis; D054879:Halogenation; D006358:Hot Temperature; D006851:Hydrochloric Acid / Q000737:chemistry; D007101:Immersion; D008855:Microscopy, Electron, Scanning; D056951:Photoelectron Spectroscopy; D012969:Sodium Fluoride / Q000737:chemistry; D013052:Spectrometry, X-Ray Emission; D017550:Spectroscopy, Fourier Transform Infrared; D013552:Swine; D013997:Time Factors; D014961:X-Ray Diffraction
chemical_list: D001672:Biocompatible Materials; D012969:Sodium Fluoride; D017886:Durapatite; D005459:Fluorides; D006851:Hydrochloric Acid