title: High numerical aperture reflection mode coherent diffraction microscopy using off-axis apertured illumination.
abstract: We extend coherent diffraction imaging (CDI) to a high numerical aperture reflection mode geometry for the first time. We derive a coordinate transform that allows us to rewrite the recorded far-field scatter pattern from a tilted object as a uniformly spaced Fourier transform. Using this approach, FFTs in standard iterative phase retrieval algorithms can be used to significantly speed up the image reconstruction times. Moreover, we avoid the isolated sample requirement by imaging a pinhole onto the specimen, in a technique termed apertured illumination CDI. By combining the new coordinate transformation with apertured illumination CDI, we demonstrate rapid high numerical aperture imaging of samples illuminated by visible laser light. Finally, we demonstrate future promise for this technique by using high harmonic beams for high numerical aperture reflection mode imaging.
authors.affiliation: JILA, University of Colorado, 440 UCB, Boulder, Colorado 80309-0440, USA. dennis.gardner@colorado.edu
authors.forename: Dennis F
authors.initials: DF
authors.lastname: Gardner
authors.forename: Bosheng
authors.initials: B
authors.lastname: Zhang
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Seaberg
authors.forename: Leigh S
authors.initials: LS
authors.lastname: Martin
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Adams
authors.forename: Farhad
authors.initials: F
authors.lastname: Salmassi
authors.forename: Eric
authors.initials: E
authors.lastname: Gullikson
authors.forename: Henry
authors.initials: H
authors.lastname: Kapteyn
authors.forename: Margaret
authors.initials: M
authors.lastname: Murnane
mesh_terms: D000465:Algorithms; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008029:Lighting / Q000379:methods*; D046529:Microscopy, Electron, Transmission / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity