title: Metal-free direct amination/aromatization of 2-cyclohexenones to iodo-N-arylanilines and N-arylanilines promoted by iodine.
abstract: An iodine mediated aromatization leading to a one-pot synthesis of iodo-N-arylanilines and N-arylanilines is reported. This highly regioselective aliphatic-aromatic transformation can be performed with various combinations of 2-cyclohexenones and anilines. The presence of a directing group is crucial for achieving high yields.
authors.affiliation: Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Monte da Caparica, Portugal.
authors.forename: M Teresa
authors.initials: MT
authors.lastname: Barros
authors.forename: Suvendu S
authors.initials: SS
authors.lastname: Dey
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Maycock
authors.forename: Paula
authors.initials: P
authors.lastname: Rodrigues
mesh_terms: D000586:Amination; D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D003512:Cyclohexanones / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry*
chemical_list: D000814:Aniline Compounds; D003512:Cyclohexanones; C028215:2-cyclohexen-1-one; D007455:Iodine