title: Interactions in the aetiology, presentation and management of synchronous and metachronous adenocarcinoma of the prostate and rectum.
abstract: Adenocarcinoma of the prostate and rectum are common male pelvic cancers and may present synchronously or metachronously due to their anatomic proximity. The treatment of rectal or prostate cancer (in particular surgery and/or radiotherapy) may alter the presentation, incidence and  management should a metachronous tumour develop. This review focuses on the interaction between prostatic and rectal cancer diagnosis and management. We have restricted the scope of this large topic to general considerations, management of rectal cancer after prostate cancer treatment and  vice versa, management of synchronous disease and cancer follow-up issues.
authors.affiliation: Poole Hospital NHS Foundation Trust, Dorset, UK. guy.nash@poole.nhs.uk
authors.forename: G F
authors.initials: GF
authors.lastname: Nash
authors.forename: K J
authors.initials: KJ
authors.lastname: Turner
authors.forename: T
authors.initials: T
authors.lastname: Hickish
authors.forename: J
authors.initials: J
authors.lastname: Smith
authors.forename: M
authors.initials: M
authors.lastname: Chand
authors.forename: B J
authors.initials: BJ
authors.lastname: Moran
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary; D016609:Neoplasms, Second Primary; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000628:therapy