title: Medicine. Drug trial offers uncertain start in race to save children with progeria.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Couzin-Frankel
mesh_terms: D000818:Animals; D002675:Child, Preschool; D002986:Clinical Trials as Topic / Q000191:economics* / Q000706:statistics & numerical data*; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D051231:Farnesyltranstransferase / Q000037:antagonists & inhibitors; D005582:Foundations / Q000458:organization & administration; D006801:Humans; D034904:Lamin Type A / Q000235:genetics; D051379:Mice; D009154:Mutation; D018579:Patient Selection; D010880:Piperidines / Q000627:therapeutic use*; D011371:Progeria / Q000188:drug therapy* / Q000191:economics / Q000235:genetics*; D011725:Pyridines / Q000627:therapeutic use*; D035501:Uncertainty; D014481:United States; D014492:United States Public Health Service; D003986:Dibenzocycloheptenes
chemical_list: D004791:Enzyme Inhibitors; D051231:Farnesyltranstransferase; D034904:Lamin Type A; D010880:Piperidines; D011725:Pyridines; C494847:LMNA protein, human; C115354:lonafarnib; D003986:Dibenzocycloheptenes