title: Outcome of conservative treatment and subsequent assisted reproductive technology for patients with early-stage endometrial adenocarcinoma and poor fertility potential.
abstract: Conservative treatment with high doses of progestin is an alternative to standard hysterectomy for young patients with early-stage endometrial adenocarcinoma who desire to preserve their fertility. Here we report a patient with well-differentiated early-stage endometrial adenocarcinoma and poor fertility potential who failed to become pregnant in two in vitro fertilization-embryo transfer cycles and suffered a relapse after conservative treatment. This case illustrates that assessment of fertility potential is critical at the time of initial evaluation and conservative treatment planning for patients with endometrial adenocarcinoma.
authors.affiliation: Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, Zhejiang University, Zhejiang, Hangzhou, Zhejiang 310016, China.
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: Tong
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Zhu
authors.forename: Xiao-Na
authors.initials: XN
authors.lastname: Lin
authors.forename: Ling-Ying
authors.initials: LY
authors.lastname: Jiang
authors.forename: Wei-Hai
authors.initials: WH
authors.lastname: Xu
authors.forename: Liu
authors.initials: L
authors.lastname: Liu
authors.forename: Song-Ying
authors.initials: SY
authors.lastname: Zhang
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000378:metabolism; D000328:Adult; D018931:Antineoplastic Agents, Hormonal; D016889:Endometrial Neoplasms / Q000188:drug therapy* / Q000378:metabolism*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000627:therapeutic use; D006062:Gonadotropins / Q000627:therapeutic use; D006801:Humans; D007246:Infertility; D011247:Pregnancy; D011374:Progesterone / Q000627:therapeutic use; D027724:Reproductive Techniques, Assisted
chemical_list: D018931:Antineoplastic Agents, Hormonal; D006062:Gonadotropins; D011374:Progesterone; D005640:Follicle Stimulating Hormone