title: Leflunomide in systemic onset Juvenile idiopathic arthritis.
abstract: Methotrexate, the mainstay of treatment in Juvenile idiopathic arthritis, might not be effective in a few patients of polyarticular and systemic onset juvenile idiopathic arthritis. Use of biologicals like TNF-a blockers, the next line of preferred drugs is constrained by the high cost. We successfully used leflunomide in four patients.
authors.affiliation: Department of Paediatrics, Post Graduate Institute of Medical Education and Research, Dr Ram Manohar Lohia hospital, New Delhi, India.
authors.forename: Afsana
authors.initials: A
authors.lastname: Jahan
authors.forename: Vivek
authors.initials: V
authors.lastname: Dewan
authors.forename: Tribhuvan Pal
authors.initials: TP
authors.lastname: Yadav
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001171:Arthritis, Juvenile / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007555:Isoxazoles / Q000627:therapeutic use*; D000077339:Leflunomide; D008297:Male
chemical_list: D018501:Antirheumatic Agents; D007555:Isoxazoles; D000077339:Leflunomide