title: [The biliary complications in live donor liver transplant do not affect the long-term results].
abstract: BACKGROUND
  Living donor liver transplantation (LDLT) is an effective treatment for patients with terminal chronic liver disease, despite the high incidence of biliary complications. The objective is to evaluate the results and long-term impact of biliary complications after THDV.
  
  
  METHODS
  From 2000 to 2010, 70 right lobe LDLT were performed. Biliary complications (leakage and stenosis) of the 70 LDLT recipients were collected prospectively and analyzed retrospectively.
  
  
  RESULTS
  A total of 39 patients (55.7%) had some type of biliary complication. Twenty nine presented a leak, and of these, 14 subsequently developed a stricture. In addition, 10 patients had a stenosis without prior leakage. The median time to onset of stenosis was almost a year. Patients with previous biliary leakage were more likely to develop stenosis (58% vs. 29.5% at 5 years, P=.05). With a median follow up of 80 months, 70.8% of patients were successfully treated by interventional radiology. After excluding early mortality, there were no differences in survival according to biliary complications. A decrease of biliary complications was observed in the last 35 patients compared with the first 35.
  
  
  CONCLUSIONS
  LDLT is associated with a high incidence of biliary complications. However, long-term outcome of patients is not affected. After a median follow-up time of nearly seven years, no differences were found in survival according to the presence of biliary complications.
authors.affiliation: Unidad de Cirugía Hepatobiliopancreática y Trasplante, Hospital Clínic de Barcelona, Barcelona, España.
authors.forename: Santiago
authors.initials: S
authors.lastname: Sánchez Cabús
authors.forename: David
authors.initials: D
authors.lastname: Calatayud
authors.forename: Raquel
authors.initials: R
authors.lastname: García-Roca
authors.forename: Joana
authors.initials: J
authors.lastname: Ferrer
authors.forename: Josep
authors.initials: J
authors.lastname: Martí
authors.forename: Miquel
authors.initials: M
authors.lastname: Navasa
authors.forename: Antoni
authors.initials: A
authors.lastname: Rimola
authors.forename: Constantino
authors.initials: C
authors.lastname: Fondevila
authors.forename: José
authors.initials: J
authors.lastname: Fuster
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: García-Valdecasas
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D057868:Anastomotic Leak / Q000453:epidemiology / Q000209:etiology; D001649:Bile Duct Diseases / Q000453:epidemiology* / Q000209:etiology* / Q000628:therapy; D001652:Bile Ducts / Q000473:pathology; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D015994:Incidence; D016031:Liver Transplantation / Q000009:adverse effects*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult