title: Intraoperative adrenal insufficiency in a patient with prader-willi syndrome.
abstract: Prader-Willi syndrome (PW) is a rare genetic disorder with multi-organ system involvement. These patients present many perioperative challenges including sleep-related breathing disorders, morbid obesity, thick salivary secretions, mental retardation, and difficult intravenous access. PW has been suggested to be associated with central adrenal insufficiency. We report a novel case of persistent severe hypotension from previously undiagnosed and asymptomatic adrenal insufficiency in a pediatric patient with Prader-Willi syndrome during spine surgery that resolved upon treatment with hydrocortisone.
authors.affiliation: Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
authors.forename: David W
authors.initials: DW
authors.lastname: Barbara
authors.forename: James D
authors.initials: JD
authors.lastname: Hannon
authors.forename: William R
authors.initials: WR
authors.lastname: Hartman