title: Neuropeptide Y and its role in CNS disease and repair.
abstract: Neuropeptide Y (NPY) is widely expressed throughout the CNS and exerts a number of important physiological functions as well as playing a role in pathological conditions such as obesity, anxiety, epilepsy, chronic pain and neurodegenerative disorders. In this review, we highlight some of the recent advances in our understanding of NPY biology and how this may help explain not only its role in health and disease, but also its possible use therapeutically.
authors.affiliation: Wallenberg Neuroscience Center, Department of Experimental Medical Sciences, Lund University, Lund, Sweden. Mickael.Decressac@med.lu.se
authors.forename: M
authors.initials: M
authors.lastname: Decressac
authors.forename: R A
authors.initials: RA
authors.lastname: Barker
mesh_terms: D000818:Animals; D002493:Central Nervous System Diseases / Q000188:drug therapy* / Q000378:metabolism* / Q000473:pathology; D000089622:Doublecortin Domain Proteins; D005786:Gene Expression Regulation / Q000187:drug effects; D006801:Humans; D008869:Microtubule-Associated Proteins / Q000378:metabolism; D055495:Neurogenesis / Q000187:drug effects; D009478:Neuropeptide Y / Q000378:metabolism* / Q000494:pharmacology / Q000627:therapeutic use*; D009479:Neuropeptides / Q000378:metabolism; D018696:Neuroprotective Agents / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D015398:Signal Transduction / Q000187:drug effects
chemical_list: D000089622:Doublecortin Domain Proteins; D008869:Microtubule-Associated Proteins; D009478:Neuropeptide Y; D009479:Neuropeptides; D018696:Neuroprotective Agents