title: Oropharyngeal Candida colonization in human immunodeficiency virus infected patients.
abstract: Oropharyngeal candidiasis (OPC) is a very common oral symptom for HIV infected patients. OPC is often caused by overgrowth of commensal Candida strains which asymptomatically colonize oral cavity of HIV+ patients. HIV infection can not only weaken the systemic and local mucosal immunity but also interact with Candida species colonizing in oral cavity. These changes in host immunity and Candida species may facilitate Candida colonization in oral cavity of HIV infected patients. This review will discuss oral Candida colonization (including asymptomatic Candida carriage and OPC) prevalence, colonization spectrum, colonization intensity, relationship between oropharyngeal Candida colonization and peripheral blood CD4+ T cell counts, association of plasma levels of HIV RNA and Candida colonization, and other factors related with Candida colonization in HIV+ patients.
authors.affiliation: State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, Chengdu, China.
authors.forename: Xiaoxu
authors.initials: X
authors.lastname: Li
authors.forename: Lei
authors.initials: L
authors.lastname: Lei
authors.forename: Dan
authors.initials: D
authors.lastname: Tan
authors.forename: Lu
authors.initials: L
authors.lastname: Jiang
authors.forename: Xin
authors.initials: X
authors.lastname: Zeng
authors.forename: Hongxia
authors.initials: H
authors.lastname: Dan
authors.forename: Ga
authors.initials: G
authors.lastname: Liao
authors.forename: Qianming
authors.initials: Q
authors.lastname: Chen
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000276:immunology / Q000382:microbiology*; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D002175:Candida / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity; D002180:Candidiasis, Oral / Q000150:complications / Q000821:virology*; D006678:HIV / Q000302:isolation & purification / Q000472:pathogenicity; D015658:HIV Infections / Q000150:complications / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D018928:Immunity, Mucosal / Q000276:immunology; D009061:Mouth Mucosa / Q000276:immunology; D009960:Oropharynx / Q000382:microbiology*; D012367:RNA, Viral / Q000302:isolation & purification
chemical_list: D012367:RNA, Viral