title: Analytical cytology: applications to neurotoxicology.
abstract: This unit describes methods for analyzing the effects of neurotoxicants on cell cycle regulation by dual parameter flow cytometry and on cell signaling by quantifying intracellular calcium concentrations within individual cells by scanning confocal laser microscopy or using the fluorescent calcium probe fluo-3.
authors.affiliation: University of Washington, Seattle, Washington, USA.
authors.forename: M C
authors.initials: MC
authors.lastname: Catlin
authors.forename: M
authors.initials: M
authors.lastname: Guizzetti
authors.forename: R A
authors.initials: RA
authors.lastname: Ponce
authors.forename: L G
authors.initials: LG
authors.lastname: Costa
authors.forename: T J
authors.initials: TJ
authors.lastname: Kavanagh
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism; D002453:Cell Cycle; D005434:Flow Cytometry; D009420:Nervous System / Q000166:cytology / Q000187:drug effects*; D009457:Neuroglia / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D051381:Rats; D018675:Toxicity Tests
chemical_list: D002118:Calcium