title: Population-based study of risk factors for coronary heart disease among HIV-infected persons.
abstract: Preventing coronary heart disease (CHD) is critical to further extending survival among human immunodeficiency virus (HIV)-infected persons. Previously published findings of CHD risk factors in HIV-infected persons have been derived from facility-based cohort studies, which have limited representativeness for the HIV-infected population. State-specific, population-based surveillance data can assist health care providers and public health agencies in planning and evaluating programs that reduce CHD among HIV-infected persons. We describe CHD risk factors from the 2007-2008 Oregon Medical Monitoring Project, a population-based survey of HIV-infected persons receiving care that included both patient interview and medical record review. Among the 539 HIV-infected patients interviewed, the mean age was 45.5 years. Diagnoses from the medical record associated with CHD risk included preexisting CHD (5%), diabetes (11%), and hypertension (28%). Current smoking was reported by 46%; college graduates were less likely to smoke compared with those with lesser education (21% versus 53%, respectively; P <.0001). Obesity was present among 17%. Among the 65% of the survey group with lipid values available, 55% had high-density lipoprotein cholesterol (HDL) <40 mg/dL and 42% had triglycerides ≥ 200 mg/dL. Among the 15% of the survey group with either preexisting CHD or diabetes, 42% had a non-HDL <130 mg/dL (target goal) and 38% smoked. Risk factors for CHD among HIVinfected persons, particularly smoking and dyslipidemia, should be managed aggressively. Ongoing surveillance is warranted to monitor changes in CHD risk factors in the HIV-infected population.
authors.affiliation: Epidemic Intelligence Service, Centers for Disease Control and Prevention, Portland, Oregon, USA ; Oregon Public Health Division, Portland, Oregon, USA.
authors.forename: John Y
authors.initials: JY
authors.lastname: Oh
authors.forename: Kari
authors.initials: K
authors.lastname: Greene
authors.forename: Haiou
authors.initials: H
authors.lastname: He
authors.forename: Sean
authors.initials: S
authors.lastname: Schafer
authors.forename: Katrina
authors.initials: K
authors.lastname: Hedberg