title: Glycopolymers and glyco-nanoparticles in biomolecular recognition processes and vaccine development.
abstract: With advances in polymerization techniques as well as selective chemical modification of carbohydrates, glycopolymers and glyco-nanoparticles are emerging as an important class of materials with tailored properties or novel nanotechnology-based platforms for a number of applications. The field of the so-called glyco-nanotechnology is starting to show some promises for future clinical applications. Glyco-nanoparticles, due to their versatile nature, could offer a platform for the design of carbohydrate-based vaccines and possibly allow the development of new single-dose vaccines in disease areas of unmet need. This paper surveys the emerging roles of carbohydrate-based polymeric and nanomaterials for biomolecular recognition processes and vaccine development.
authors.affiliation: Department of Chemistry, Brandon University, Brandon, MB R7A 6A9, Canada.
authors.forename: Rajesh
authors.initials: R
authors.lastname: Sunasee
authors.forename: Ravin
authors.initials: R
authors.lastname: Narain
mesh_terms: D000937:Antigen-Antibody Reactions; D002241:Carbohydrates / Q000737:chemistry* / Q000276:immunology*; D015195:Drug Design; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry; D036103:Nanotechnology; D058105:Polymerization; D011108:Polymers / Q000737:chemistry; D014612:Vaccines / Q000737:chemistry / Q000276:immunology
chemical_list: D002241:Carbohydrates; D011108:Polymers; D014612:Vaccines