title: Regulation of metabolism: a cross talk between gut microbiota and its human host.
abstract: The recent epidemic of obesity and diabetes and the diversity at the individual level could be explained by the intestinal microbiota-to-host relationship. More than four million gene products from the microbiome could interact with the immune system to induce a tissue metabolic infection, which is the molecular origin of the low-grade inflammation that characterizes the onset of obesity and diabetes.
authors.affiliation: Institut National de la Santé et de la Recherche Médicale INSERM, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France. remy.burcelin@inserm.fr
authors.forename: Rémy
authors.initials: R
authors.lastname: Burcelin
mesh_terms: D003920:Diabetes Mellitus / Q000503:physiopathology; D041981:Gastrointestinal Tract / Q000382:microbiology* / Q000502:physiology; D006801:Humans; D007107:Immune System / Q000502:physiology; D008659:Metabolic Diseases / Q000503:physiopathology; D008660:Metabolism / Q000502:physiology*; D054892:Metagenome / Q000502:physiology*; D009765:Obesity / Q000503:physiopathology