title: Iron-catalyzed chemo- and stereoselective hydromagnesiation of diarylalkynes and diynes.
abstract: Diarylalkynes are chemo- and stereoselectively hydromagnesiated in high yields at room temperature with an iron species generated in situ from FeCl(2)and EtMgBr. Functional groups such as bromide, iodide, amine, phenoxide, and alkene are well tolerated. Under similar conditions, diynes are chemo-, regio-, and stereoselectively hydromagnesiated. The resulting alkenylmagnesium compounds are a platform for further functionalization as a one-pot reaction.
authors.affiliation: Department of Chemistry, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
authors.forename: Laurean
authors.initials: L
authors.lastname: Ilies
authors.forename: Takumi
authors.initials: T
authors.lastname: Yoshida
authors.forename: Eiichi
authors.initials: E
authors.lastname: Nakamura
mesh_terms: D000475:Alkenes / Q000138:chemical synthesis / Q000737:chemistry; D000480:Alkynes / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D005296:Ferrous Compounds / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D000480:Alkynes; D005296:Ferrous Compounds; D009942:Organometallic Compounds; C029451:ferrous chloride