title: Isolation of cerebellar granule cells from neonatal rats.
abstract: Cerebellar Granule Cells in Neurotoxicology (Jan Oberdoerster, Aventis Corporation, Research Triangle Park, North Carolina). Cultured neurons allow the researcher to investigate mechanisms of toxicity on a relatively uniform population of cells. Primary cultures of cerebellar granule cells are post-mitotic neurons that are readily isolated and may be used for experimental procedures including electrophysiology, neuronal maturation, and various biochemical and molecular analyses.
authors.affiliation: Aventis CropScience, Research Triangle Park, NC, USA.
authors.forename: J
authors.initials: J
authors.lastname: Oberdoerster
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D002469:Cell Separation; D002478:Cells, Cultured; D002531:Cerebellum / Q000166:cytology*; D003594:Cytoplasmic Granules; D051381:Rats; D017207:Rats, Sprague-Dawley