title: Recyclable fluorous cinchona alkaloid ester as a chiral promoter for asymmetric fluorination of β-ketoesters.
abstract: A fluorous cinchona alkaloid ester has been developed as a chiral promoter for the asymmetric fluorination of β-ketoesters. It has comparable reactivity and selectivity to the nonfluorous versions of cinchona alkaloids and can be easily recovered from the reaction mixture by simple fluorous solid-phase extraction (F-SPE) and used for the next round of reaction without further purification.
authors.affiliation: School of Chemical Engineering, Nanjing University of Science and Technology, Xiao Ling Wei Street, Nanjing 210094, People's Republic of China.
authors.forename: Wen-Bin
authors.initials: WB
authors.lastname: Yi
authors.forename: Xin
authors.initials: X
authors.lastname: Huang
authors.forename: Zijuan
authors.initials: Z
authors.lastname: Zhang
authors.forename: Dian-Rong
authors.initials: DR
authors.lastname: Zhu
authors.forename: Chun
authors.initials: C
authors.lastname: Cai
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang