title: Stress-induced cardiomyopathy (takotsubo cardiomyopathy) after liver transplantation-report of two cases.
abstract: Cardiac complications after liver transplantation are a common cause of death. Stress-induced cardiomyopathy, also called takotsubo cardiomyopathy, is a special form of cardiomyopathy that is precipitated by a stress situation. It can occur after a surgical procedure that results in acute heart failure. Herein we have presented 2 cases of reversible stress-induced cardiac dysfunction early in the period after liver transplantation. Before surgery, cardiac evaluation was normal, with both patients classified as low risk for cardiovascular events during the proposed procedure. Both patients experienced cardiac arrest after graft reperfusion with return of spontaneous circulation after resuscitation. Their early periods after transplantation were characterized by cardiogenic shock secondary to important ventricular dysfunction requiring vasoactive drugs. Subsequent investigations excluded coronary disease. The diagnosis of takotsubo cardiomyopathy was established based on the clinical features and ancillary tests, particularly echocardiography showing apical ballooning. In both cases, ventricular function recovered completely. In conclusion, stress-induced cardiomyopathy, an underestimated cause of heart complications, should be considered as a possible cause of cardiac failure in liver transplant patients.
authors.affiliation: Organ Transplantation Integrated Program, Albert Einstein Hospital, São Paulo, Brazil.
authors.forename: L J
authors.initials: LJ
authors.lastname: Tachotti Pires
authors.forename: M N
authors.initials: MN
authors.lastname: Cardoso Curiati
authors.forename: F
authors.initials: F
authors.lastname: Vissoci Reiche
authors.forename: O M
authors.initials: OM
authors.lastname: Silvestre
authors.forename: S
authors.initials: S
authors.lastname: Mangini
authors.forename: R
authors.initials: R
authors.lastname: Carballo Afonso
authors.forename: B H
authors.initials: BH
authors.lastname: Ferraz-Neto
authors.forename: F
authors.initials: F
authors.lastname: Bacal
mesh_terms: D000328:Adult; D017809:Fatal Outcome; D005260:Female; D006323:Heart Arrest / Q000209:etiology; D006333:Heart Failure / Q000209:etiology; D006439:Hemodynamics; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D020127:Recovery of Function; D012770:Shock, Cardiogenic / Q000209:etiology; D013318:Stroke Volume; D054549:Takotsubo Cardiomyopathy / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D016896:Treatment Outcome; D014463:Ultrasonography; D016277:Ventricular Function, Left