title: Imaging the inflammatory activity of sarcoidosis.
abstract: Accurate assessment of pulmonary and extrapulmonary organ involvement in sarcoidosis is one of the great challenges for clinicians. This assessment includes the evaluation of symptoms and of sarcoidosis activity in a specific organ and its functional consequences. In this review, radiological and nuclear techniques to image the inflammatory activity of sarcoidosis are described, in particular (18)F-FDG positron emission tomography/computed tomography. The current use of this technique in clinical practice is explained, particularly in patients with persistent symptoms, stage IV disease and cardiac sarcoidosis.
authors.affiliation: St Antonius Hospital, Nieuwegein, The Netherlands.
authors.forename: Ruth G M
authors.initials: RG
authors.lastname: Keijsers
authors.forename: Daniel A F
authors.initials: DA
authors.lastname: van den Heuvel
authors.forename: Jan C
authors.initials: JC
authors.lastname: Grutters
mesh_terms: D019788:Fluorodeoxyglucose F18 / Q000494:pharmacology; D005710:Gallium Radioisotopes / Q000494:pharmacology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007249:Inflammation / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D049268:Positron-Emission Tomography; D013902:Radiography, Thoracic; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000494:pharmacology; D017481:Receptors, Somatostatin / Q000378:metabolism; D012507:Sarcoidosis / Q000175:diagnosis* / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed
chemical_list: D005710:Gallium Radioisotopes; D007166:Immunosuppressive Agents; D019275:Radiopharmaceuticals; D017481:Receptors, Somatostatin; D019788:Fluorodeoxyglucose F18