title: Sensitive SERS detection of DNA and lysozyme based on polymerase assisted cross strand-displacement amplification.
abstract: A novel surface-enhanced Raman scattering (SERS) assay is demonstrated by developing a cross strand-displacement amplification (CSDA) method to enhance the SERS signals. Highly sensitive and selective detection of any single-stranded DNA is achieved and an aptasensor for proteins is constructed.
authors.affiliation: Key Laboratory of Biochemical Analysis, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
authors.forename: Chengcun
authors.initials: C
authors.lastname: Lei
authors.forename: Yan
authors.initials: Y
authors.lastname: Zeng
authors.forename: Xiaoting
authors.initials: X
authors.lastname: Ji
authors.forename: Shusheng
authors.initials: S
authors.lastname: Zhang
mesh_terms: D004247:DNA / Q000032:analysis*; D004259:DNA-Directed DNA Polymerase / Q000737:chemistry; D006801:Humans; D009113:Muramidase / Q000032:analysis*; D044967:Serum / Q000737:chemistry; D013059:Spectrum Analysis, Raman
chemical_list: D004247:DNA; D004259:DNA-Directed DNA Polymerase; D009113:Muramidase