title: Neurosurgical treatment of Cushing disease.
abstract: Cushing disease (CD) is caused by overproduction of adrenocorticotropin by a pituitary adenoma (or, rarely, carcinoma). The diagnosis of CD requires distinguishing it from other hypercortisolemic states with a thorough endocrine workup. CD remains a primarily surgical disease, with remission rates of 70% to 95% following microscopic or endoscopic transsphenoidal surgery.
authors.affiliation: Department of Neurosurgery, Massachusetts General Hospital, Boston, MA 02114, USA.
authors.forename: Sameer A
authors.initials: SA
authors.lastname: Sheth
authors.forename: Sarah K
authors.initials: SK
authors.lastname: Bourne
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Tritos
authors.forename: Brooke
authors.initials: B
authors.lastname: Swearingen
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives / Q000378:metabolism; D006801:Humans; D019635:Neurosurgical Procedures; D047748:Pituitary ACTH Hypersecretion / Q000209:etiology / Q000532:radiotherapy / Q000601:surgery*; D010911:Pituitary Neoplasms / Q000150:complications / Q000532:radiotherapy / Q000601:surgery; D055502:Secondary Prevention; D016896:Treatment Outcome
chemical_list: D000324:Adrenocorticotropic Hormone