title: Increased thiamine intake may be required to maintain thiamine status during weight loss in patients with type 2 diabetes.
abstract: During weight loss, erythrocyte thiamine pyrophosphate (TPP) decreased (221±52 to 195±39 nmol/L, P<0.05) on a diet with adequate thiamine (1.1 mg/day) but was unchanged (217±55 vs 218±52 nmol/L, NS) on a high thiamine diet (2.8 mg/day). Attention to thiamine status may be required in patients with diabetes after weight loss.
authors.affiliation: Commonwealth Scientific and Industrial Research Organisation Food and Nutritional Sciences, Adelaide, Australia. Jennifer.keogh@unisa.edu.au
authors.forename: Jennifer B
authors.initials: JB
authors.lastname: Keogh
authors.forename: X
authors.initials: X
authors.lastname: Cleanthous
authors.forename: T P
authors.initials: TP
authors.lastname: Wycherley
authors.forename: G D
authors.initials: GD
authors.lastname: Brinkworth
authors.forename: M
authors.initials: M
authors.lastname: Noakes
authors.forename: Peter M
authors.initials: PM
authors.lastname: Clifton
mesh_terms: D000818:Animals; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D004038:Diet, Reducing / Q000009:adverse effects*; D004044:Dietary Proteins / Q000008:administration & dosage; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D005527:Food, Fortified / Q000032:analysis; D006801:Humans; D057194:Intention to Treat Analysis; D008297:Male; D008460:Meat / Q000032:analysis; D008875:Middle Aged; D009520:New Zealand; D009765:Obesity / Q000097:blood / Q000150:complications / Q000178:diet therapy*; D050177:Overweight / Q000097:blood / Q000150:complications / Q000178:diet therapy*; D010352:Patient Dropouts; D034421:Sus scrofa; D013831:Thiamine / Q000627:therapeutic use*; D013832:Thiamine Deficiency / Q000209:etiology / Q000517:prevention & control*; D013835:Thiamine Pyrophosphate / Q000097:blood; D015431:Weight Loss
chemical_list: D004044:Dietary Proteins; D013835:Thiamine Pyrophosphate; D013831:Thiamine