title: [Duodenal levodopa infusion for advanced Parkinson's disease in Finland 2006-2010].
abstract: BACKGROUND
  Deep brain stimulation (DBS) has been used for treatment of advanced Parkinson's disease (PD) since 1990's. Duodenal levodopa infusion (DLI) has been available since 2006.
  
  
  METHODS
  Patient records of DLI patients and clinical data of DBS patients from 2006-2010 were requested from all university and central hospitals in Finland.
  
  
  RESULTS
  DLI was tested on 105 patients. 84 had a favourable response and were on long-term treatment. 85 patients underwent DBS operation. Technical problems and complications were common in DLI treated patients.
  
  
  CONCLUSIONS
  DLI has become as popular as DBS in the treatment of advanced PD, but has a quite high complication rate.
authors.affiliation: Kansaneläkelaitos, terveysosasto.
authors.forename: Ville
authors.initials: V
authors.lastname: Pursiainen
authors.forename: Eero
authors.initials: E
authors.lastname: Pekkonen
mesh_terms: D000978:Antiparkinson Agents / Q000008:administration & dosage*; D046690:Deep Brain Stimulation; D004386:Duodenum; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D007263:Infusions, Parenteral; D007980:Levodopa / Q000008:administration & dosage*; D008297:Male; D010300:Parkinson Disease / Q000188:drug therapy* / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D000978:Antiparkinson Agents; D007980:Levodopa