title: Lyme endocarditis.
abstract: Lyme borreliosis is a common tick-borne disease with a wide variety of clinical manifestations. Cardiac involvement has been reported during both the acute phase (atrioventricular block, pericarditis) and the chronic stage (dilated cardiomyopathy), but is rare (<5%). Here we describe the first case of Borrelia afzelii Lyme endocarditis, in a 61-year-old man living in an endemic area of France. The diagnosis was confirmed by detection of B. afzelii DNA in the mitral valve by specific real-time PCR. He was treated empirically with amoxicillin for 6 weeks and remains well 12 months later.
authors.affiliation: CHU Limoges, Laboratoire de Bactériologie-Virologie-Hygiène, Limoges, France.
authors.forename: N
authors.initials: N
authors.lastname: Hidri
authors.forename: O
authors.initials: O
authors.lastname: Barraud
authors.forename: S
authors.initials: S
authors.lastname: de Martino
authors.forename: F
authors.initials: F
authors.lastname: Garnier
authors.forename: F
authors.initials: F
authors.lastname: Paraf
authors.forename: C
authors.initials: C
authors.lastname: Martin
authors.forename: S
authors.initials: S
authors.lastname: Sekkal
authors.forename: M
authors.initials: M
authors.lastname: Laskar
authors.forename: B
authors.initials: B
authors.lastname: Jaulhac
authors.forename: M-C
authors.initials: MC
authors.lastname: Ploy
mesh_terms: D000658:Amoxicillin / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D015748:Borrelia burgdorferi Group / Q000302:isolation & purification*; D004269:DNA, Bacterial / Q000235:genetics / Q000302:isolation & purification; D004697:Endocarditis, Bacterial / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D005602:France; D006801:Humans; D008193:Lyme Disease / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000382:microbiology; D060888:Real-Time Polymerase Chain Reaction; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D000658:Amoxicillin