title: Invasive rhino-orbital aspergillosis.
abstract: Invasive aspergillosis usually affects immune-compromised patients and is common in diabetics. Proptosis, visual loss and ophthalmoplegia due to intra-orbital extension are common presentations. Three out of five patients in our series were immune-compromised. All the patients had visual loss and three patients presented with unilateral blindness. Three patients were treated by surgical debridement followed by Amphotericin B therapy. Two patients who had intra-cranial extension of the disease died during the treatment. Only one patient had improvement in vision following the treatment. High index of suspicion in immune-compromised patients, early diagnosis and prompt aggressive treatment is required to achieve clinical cure.
authors.affiliation: Government Medical College & Hospital, Chandigarh, India.
authors.forename: Vipin
authors.initials: V
authors.lastname: Arora
authors.forename: Nitin M
authors.initials: NM
authors.lastname: Nagarkar
authors.forename: Arjun
authors.initials: A
authors.lastname: Dass
authors.forename: Arvind
authors.initials: A
authors.lastname: Malhotra