title: Synthesis and hybridization properties of oligonucleotides modified with 5-(1-aryl-1,2,3-triazol-4-yl)-2'-deoxyuridines.
abstract: Oligonucleotides modified with consecutive incorporations of 5-(1-aryl-1,2,3-triazol-4-yl)-2'-deoxyuridine monomers  display strong thermal affinity and binding specificity toward RNA targets, due to formation of chromophore arrays in the major groove.
authors.affiliation: Department of Chemistry, University of Idaho, PO Box 442343, Moscow, ID 83844-2343, USA.
authors.forename: Mamta
authors.initials: M
authors.lastname: Kaura
authors.forename: Pawan
authors.initials: P
authors.lastname: Kumar
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Hrdlicka
mesh_terms: D003857:Deoxyuridine / Q000737:chemistry*; D015394:Molecular Structure; D009841:Oligonucleotides / Q000138:chemical synthesis* / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*
chemical_list: D009841:Oligonucleotides; D014230:Triazoles; D003857:Deoxyuridine