title: Use of magnetic nanoparticles to manipulate the metabolic environment of bacteria for controlled biopolymer synthesis.
abstract: Magnetic nanoparticles (MNPs) were covalently immobilized on the surface of Acetobacter xylinus and the location of the bacteria was controlled to manipulate bacterial bioactivation. The bacteria were positioned in the middle of an incubation tube by applying an external magnetic field, and the cellulose produced at the different metabolizing locations was characterized by X-ray diffraction, electron microscopy, and differential scanning calorimetry. To the best of our knowledge, this is the first experiment in which MNPs were employed in the control of cell metabolism.
authors.affiliation: Department of Biosystems and Biomaterials Science and Engineering, Seoul National University, Seoul 151-742, Korea.
authors.forename: Minsung
authors.initials: M
authors.lastname: Park
authors.forename: SuBeom
authors.initials: S
authors.lastname: Park
authors.forename: Jinho
authors.initials: J
authors.lastname: Hyun
mesh_terms: D002482:Cellulose / Q000096:biosynthesis*; D041822:Gluconacetobacter xylinus / Q000378:metabolism*; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry
chemical_list: D058185:Magnetite Nanoparticles; D012822:Silicon Dioxide; D002482:Cellulose