title: Efficacy of calcium sodium phosphosilicate in managing dentinal hypersensitivity.
abstract: A large number of home use products have been tested and used for managing dentinal hypersensitivity. This eight-week clinical trial compared the temporal efficacy of a commercially available toothpaste containing calcium sodium phosphosilicate to that of a toothpaste containing potassium nitrate.   For this study, 20 subjects (age 18 - 65) were screened using a visual analog scale (VAS) for sensitivity to a cold stimulus. Baseline VAS sensitivity scores to tactile stimulus were recorded for a minimum of two teeth per patient. Dentifrices were prescribed for all patients and sensitivity scores were re-evaluated at two, four, and eight weeks.  Though both groups showed significant reductions in sensitivity scores, only at eight weeks was there a marginally significant difference (p = 0.0551) in sensitivity scores between the test group and the positive control group.
authors.affiliation: Department of Periodontics, SDM College of Dental Sciences & Hospital, Dharwad, Karnataka, India.
authors.forename: Sai M
authors.initials: SM
authors.lastname: Surve
authors.forename: Anirudh B
authors.initials: AB
authors.lastname: Acharya
authors.forename: Ananya
authors.initials: A
authors.lastname: Shetty
authors.forename: Srinath L
authors.initials: SL
authors.lastname: Thakur
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D002118:Calcium; D003802:Dentifrices / Q000737:chemistry* / Q000627:therapeutic use; D003807:Dentin Sensitivity / Q000175:diagnosis / Q000628:therapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009566:Nitrates / Q000627:therapeutic use*; D017680:Potassium Compounds / Q000627:therapeutic use*; D017640:Silicates; D012964:Sodium; D064232:Visual Analog Scale
chemical_list: D003802:Dentifrices; D009566:Nitrates; D017680:Potassium Compounds; D017640:Silicates; D012964:Sodium; C023844:potassium nitrate; D002118:Calcium