title: Determining biomembrane bending rigidities from simulations of modest size.
abstract: Thermal fluctuations of lipid orientation are analyzed to infer the bending rigidity of lipid bilayers directly from molecular simulations. Compared to the traditional analysis of thermal membrane undulations, the proposed method is reliable down to shorter wavelengths and allows for determination of the bending rigidity using smaller simulation boxes. The requisite theoretical arguments behind this analysis are presented and verified by simulations spanning a diverse range of lipid models from the literature.
authors.affiliation: Department of Physics, University of California, Santa Barbara, California 93106, USA.
authors.forename: Max C
authors.initials: MC
authors.lastname: Watson
authors.forename: Erik G
authors.initials: EG
authors.lastname: Brandt
authors.forename: Paul M
authors.initials: PM
authors.lastname: Welch
authors.forename: Frank L H
authors.initials: FL
authors.lastname: Brown
mesh_terms: D001696:Biomechanical Phenomena; D003198:Computer Simulation; D008051:Lipid Bilayers / Q000737:chemistry*; D008563:Membrane Lipids / Q000737:chemistry*; D008566:Membranes / Q000737:chemistry; D008954:Models, Biological; D013816:Thermodynamics
chemical_list: D008051:Lipid Bilayers; D008563:Membrane Lipids