title: Anion-induced enantioselective cyclization of diynamides to pyrrolidines catalyzed by cationic gold complexes.
abstract: Only chiral anions do the job! Optically active gold complexes derived from substituted binol hydrogen phosphate catalyze the desymmetrizing cyclization of 1,4-diynamides. This reaction provides access to synthetically useful, chiral methylene pyrrolidines with an all-carbon-substituted quaternary stereocenter.
authors.affiliation: Institute for Chemistry and Biochemistry, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany.
authors.forename: Asmaa Kamal
authors.initials: AK
authors.lastname: Mourad
authors.forename: Juliane
authors.initials: J
authors.lastname: Leutzow
authors.forename: Constantin
authors.initials: C
authors.lastname: Czekelius
mesh_terms: D000480:Alkynes / Q000737:chemistry; D000577:Amides / Q000737:chemistry*; D000838:Anions / Q000737:chemistry; D002384:Catalysis; D002412:Cations / Q000737:chemistry; D003500:Cyclization; D050607:Organogold Compounds / Q000737:chemistry*; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D000577:Amides; D000838:Anions; D002412:Cations; D050607:Organogold Compounds; D011759:Pyrrolidines