title: [Evaluation of carotis intima media thickness in chronic obstructive pulmonary disease patients].
abstract: BACKGROUND
  Chronic obstructive pulmonary disease (COPD) and atherosclerosis may occur due to similar risk factors and have a significant cause of morbidity and mortality. In this study to assess the relationship between COPD and atherosclerosis; carotid intima media thickness (CIMT) of COPD patients and adult healthy individuals with normal body mass index and metabolic parameters compared.
  
  
  METHODS
  2298 participants aged between 18-92; 46 patients diagnosed with COPD according to clinical features and pulmonary function tests the study, 47 healthy controls who do not have exclusion criteria were evaluated. Doppler ultrasound was performed for the assessment of CIMT to all participants. p values < 0.05 were considered to be significant.
  
  
  RESULTS
  Mean CIMT in COPD group and control group were 0.79 ± 0.16 mm and 0.616 ± 0.1 mm, respectively (p< 0.001). In multiple linear regression analysis that made to determine the atherosclerotic risk parameters affecting CIMT; it was found that CIMT was related to age with direct proportion (p= 0.002) and to FEV(1)% with inversely proportion (p= 0.04). In multivariate logistic regression analysis that made to determine the parameters affecting atherosclerosis; we found that any parameters were related with atherosclerosis.
  
  
  CONCLUSIONS
  Persistent low-grade systemic inflammation in COPD and atherosclerotic disease may possibly have been reported a factor in both pathologies. Early atherosclerosis and cardiovascular risks in adults with COPD increase independent of risk factors. CIMT which shows direct proportion with age and inverse proportion with FEV(1)% is a non-invasive, easily applicable and cheap method that can be used in determining the risk of atherosclerosis.
authors.affiliation: Department of Radiology, Duzce University, Duzce, Turkey. drfhbesir@gmail.com
authors.forename: Fahri Halit
authors.initials: FH
authors.lastname: Beşir
authors.forename: Leyla
authors.initials: L
authors.lastname: Yılmaz Aydın
authors.forename: Ömer
authors.initials: Ö
authors.lastname: Yazgan
authors.forename: Talha
authors.initials: T
authors.lastname: Dumlu
authors.forename: Melih Engin
authors.initials: ME
authors.lastname: Erkan
authors.forename: Elif
authors.initials: E
authors.lastname: Önder
authors.forename: Hülya
authors.initials: H
authors.lastname: Coşkun
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D050197:Atherosclerosis / Q000453:epidemiology* / Q000473:pathology*; D059168:Carotid Intima-Media Thickness; D016022:Case-Control Studies; D015897:Comorbidity; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology* / Q000473:pathology*; D012129:Respiratory Function Tests; D012307:Risk Factors; D017539:Tunica Intima / Q000000981:diagnostic imaging; D017540:Tunica Media / Q000000981:diagnostic imaging; D055815:Young Adult