title: Ionic liquid as soluble support for synthesis of 1,2,3-thiadiazoles and 1,2,3-selenadiazoles.
abstract: A convenient synthesis of 1,2,3-thiadiazoles and 1,2,3-selenadiazoles was achieved using an ionic liquid as a novel soluble support. Ionic liquid-supported sulfonyl hydrazine was synthesized and reacted with a number of ketones to afford the corresponding ionic liquid-supported hydrazones that were converted to 1,2,3-thiadiazoles in the presence of thionyl chloride. The reaction of ionic liquid-supported hydrazones with selenium dioxide in acetonitrile afforded 1,2,3-selenadiazoles. The advantages of this methodology were the ease of workup, simple reaction conditions, and high purity.
authors.affiliation: Department of Chemistry, Birla Institute of Technology and Science, Pilani 333031, Rajasthan, India. anilkumar@bits-pilani.ac.in
authors.forename: Anil
authors.initials: A
authors.lastname: Kumar
authors.forename: Manoj Kumar
authors.initials: MK
authors.lastname: Muthyala
authors.forename: Sunita
authors.initials: S
authors.lastname: Choudhary
authors.forename: Rakesh K
authors.initials: RK
authors.lastname: Tiwari
authors.forename: Keykavous
authors.initials: K
authors.lastname: Parang
mesh_terms: D052578:Ionic Liquids / Q000737:chemistry*; D015394:Molecular Structure; D016566:Organoselenium Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D012995:Solubility; D013830:Thiadiazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D052578:Ionic Liquids; D016566:Organoselenium Compounds; D013830:Thiadiazoles