title: Dietary intake, glucose metabolism and sex hormones in women with polycystic ovary syndrome (PCOS) compared with women with non-PCOS-related infertility.
abstract: The present study investigated dietary intake, glucose metabolism and sex hormones in women with polycystic ovary syndrome (PCOS). A total of forty-five women (aged 25–40 years) with PCOS and 161 control women (aged 25–43 years) with non-PCOS-related infertility were recruited. Anthropometry, glucose tolerance and sex hormones were determined and dietary intake was assessed. Women with PCOS had lower serum sex hormone-binding globulin and increased BMI, waist:hip ratio, luteinising hormone, ratio of luteinising hormone: follicle-stimulating hormone, testosterone and free androgen index (FAI). Postprandial glucose, fasting insulin and insulin resistance were elevated in women with PCOS. Women with PCOS had reduced energy and carbohydrate intake but higher fat intake. Serum sex hormone-binding globulin level was negatively associated with BMI in both groups and negatively correlated with macronutrient intake in the PCOS group with hyperandrogenism. However, FAI was positively correlated with BMI, waist circumference and glucose metabolic parameters in both groups. Therefore, women with PCOS consume lower energy and carbohydrate compared with those with non-PCOS-related infertility and macronutrient intake is only negatively associated with serum sex hormone-binding globulin level in the PCOS group with hyperandrogenism.
authors.affiliation: School of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan, ROC.
authors.forename: Ya-Hui
authors.initials: YH
authors.lastname: Tsai
authors.forename: Ting-Wen
authors.initials: TW
authors.lastname: Wang
authors.forename: Hsiao-Jui
authors.initials: HJ
authors.lastname: Wei
authors.forename: Chien-Yeh
authors.initials: CY
authors.lastname: Hsu
authors.forename: Hsin-Jung
authors.initials: HJ
authors.lastname: Ho
authors.forename: Wen-Hua
authors.initials: WH
authors.lastname: Chen
authors.forename: Robert
authors.initials: R
authors.lastname: Young
authors.forename: Chian-Mey
authors.initials: CM
authors.lastname: Liaw
authors.forename: Jane C-J
authors.initials: JC
authors.lastname: Chao
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D015992:Body Mass Index; D016022:Case-Control Studies; D004032:Diet; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D007246:Infertility / Q000097:blood / Q000209:etiology*; D007333:Insulin Resistance / Q000502:physiology*; D009765:Obesity / Q000097:blood / Q000150:complications*; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000150:complications* / Q000378:metabolism; D012738:Sex Hormone-Binding Globulin / Q000032:analysis
chemical_list: D012739:Gonadal Steroid Hormones; D012738:Sex Hormone-Binding Globulin