title: Quality of life after an esophagectomy.
abstract: Specialized centers have reduced the adverse outcomes associated with esophagectomy in the last 2 decades and now report operative mortalities of less than 5%. With the expanding use of screening endoscopy, early invasive esophageal adenocarcinoma is diagnosed more commonly. As a result, more patients enjoy long-term survival after curative resection. Simultaneously, emerging evidence supports the equivalence of competing endoscopic therapies for treatment of very early cancers and benign diseases. Accordingly, surgical resection requires re-evaluation using enhanced parameters to enable more meaningful comparative outcome analyses. This article summarizes the current evidence and examines future directions regarding esophagectomy quality of life.
authors.affiliation: Department of Surgical Oncology, Roswell Park Cancer Institute, University at Buffalo, Buffalo, NY 14263, USA.
authors.forename: Sartaj S
authors.initials: SS
authors.lastname: Sanghera
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Nurkin
authors.forename: Todd L
authors.initials: TL
authors.lastname: Demmy
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery* / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000601:surgery* / Q000628:therapy; D059186:Chemoradiotherapy, Adjuvant; D004938:Esophageal Neoplasms / Q000601:surgery* / Q000628:therapy; D016629:Esophagectomy / Q000379:methods*; D004944:Esophagoplasty; D004945:Esophagoscopy; D006801:Humans; D020360:Neoadjuvant Therapy; D011183:Postoperative Complications; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome