title: The effects of environmental factors on the virulence of Trichomonas vaginalis.
abstract: This review focused on potential regulatory mechanisms of Trichomonas vaginalis virulence properties, cytoadherence, cytotoxicity, phagocytosis, hemolysis, induction of apoptosis, and immune evasion in response to environmental factors of the human urogenital tract, iron, zinc, and polyamines. Understanding the multifactorial nature of trichomonal pathogenesis and its regulation may help to unravel the survival strategies of trichomonads and to implement prevention policies, opportune diagnosis, and alternative treatments for control of trichomoniasis.
authors.affiliation: Departamento de Infectómica y Patogénesis Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Av. IPN # 2508, Col. San Pedro Zacatenco, México, D.F., CP 07360, Mexico.
authors.forename: Elisa E
authors.initials: EE
authors.lastname: Figueroa-Angulo
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Rendón-Gandarilla
authors.forename: Jonathan
authors.initials: J
authors.lastname: Puente-Rivera
authors.forename: Jaeson S
authors.initials: JS
authors.lastname: Calla-Choque
authors.forename: Rosa E
authors.initials: RE
authors.lastname: Cárdenas-Guerra
authors.forename: Jaime
authors.initials: J
authors.lastname: Ortega-López
authors.forename: Laura I
authors.initials: LI
authors.lastname: Quintas-Granados
authors.forename: M Elizbeth
authors.initials: ME
authors.lastname: Alvarez-Sánchez
authors.forename: Rossana
authors.initials: R
authors.lastname: Arroyo
mesh_terms: D005260:Female; D006801:Humans; D014247:Trichomonas Vaginitis / Q000378:metabolism / Q000469:parasitology*; D014246:Trichomonas vaginalis / Q000378:metabolism / Q000472:pathogenicity*; D037521:Virulence Factors / Q000378:metabolism / Q000502:physiology*
chemical_list: D037521:Virulence Factors