title: Connection between genetic and clinical data in bipolar disorder.
abstract: Complex diseases may be associated with combinations of changes in DNA, where the single change has little impact alone. In a previous study of patients with bipolar disorder and controls combinations of SNP genotypes were analyzed, and four large clusters of combinations were found to be significantly associated with bipolar disorder. It has now been found that these clusters may be connected to clinical data.
authors.affiliation: Laboratory of Neuropsychiatry, Department of Neuroscience and Pharmacology, University of Copenhagen, Blegdamsvej, Copenhagen, Denmark. mellerup@sund.ku.dk
authors.forename: Erling
authors.initials: E
authors.lastname: Mellerup
authors.forename: Ole
authors.initials: O
authors.lastname: Andreassen
authors.forename: Bente
authors.initials: B
authors.lastname: Bennike
authors.forename: Henrik
authors.initials: H
authors.lastname: Dam
authors.forename: Srdjan
authors.initials: S
authors.lastname: Djurovic
authors.forename: Srdjan
authors.initials: S
authors.lastname: Durovic
authors.forename: Thomas
authors.initials: T
authors.lastname: Hansen
authors.forename: Ingrid
authors.initials: I
authors.lastname: Melle
authors.forename: Gert Lykke
authors.initials: GL
authors.lastname: Møller
authors.forename: Ole
authors.initials: O
authors.lastname: Mors
authors.forename: Pernille
authors.initials: P
authors.lastname: Koefoed
mesh_terms: D001714:Bipolar Disorder / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005838:Genotype; D006801:Humans; D008297:Male; D020641:Polymorphism, Single Nucleotide / Q000235:genetics