title: Interplay between protein carbonylation and nitrosylation in plants.
abstract: ROS and reactive nitrogen species (RNS) are key regulators of redox homeostasis in living organisms including plants. As control of redox homeostasis plays a central function in plant biology, redox proteomics could help in characterizing the potential roles played by ROS/RNS-induced posttranslational modification in plant cells. In this review, we focus on two posttranslational modifications: protein carbonylation (a marker of protein oxidation) and protein S-nitrosylation, both of which having recently emerged as important regulatory mechanisms during numerous fundamental biological processes. Here, we describe the recent progress in proteomic analysis of carbonylated and nitrosylated proteins and highlight the achievements made in understanding the physiological basis of these oxy/nitro modifications in plants. In addition, we document the existence of a relationship between ROS-based carbonylation and RNS-based nitrosylation thus supporting the finding that crosstalk between cellular signaling stress pathways induced by ROS and RNS could be mediated by specific protein modifications.
authors.affiliation: Laboratory of Excellence Saclay Plant Sciences (LabEx SPS), Jean-Pierre Bourgin Institute, INRA, Versailles, France.
authors.forename: Imen
authors.initials: I
authors.lastname: Lounifi
authors.forename: Erwann
authors.initials: E
authors.lastname: Arc
authors.forename: Athanassios
authors.initials: A
authors.lastname: Molassiotis
authors.forename: Dominique
authors.initials: D
authors.lastname: Job
authors.forename: Loïc
authors.initials: L
authors.lastname: Rajjou
authors.forename: Georgia
authors.initials: G
authors.lastname: Tanou
mesh_terms: D000818:Animals; D006801:Humans; D018384:Oxidative Stress; D010940:Plant Proteins / Q000378:metabolism*; D010944:Plants / Q000378:metabolism*; D050050:Protein Carbonylation; D011499:Protein Processing, Post-Translational; D026361:Reactive Nitrogen Species / Q000378:metabolism; D017382:Reactive Oxygen Species / Q000378:metabolism; D026403:S-Nitrosothiols / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D010940:Plant Proteins; D026361:Reactive Nitrogen Species; D017382:Reactive Oxygen Species; D026403:S-Nitrosothiols