title: [Experimental justification of possible mechanisms of action of low intensity electromagnetic radiation (EMR) on animals' behavior].
abstract: Effects of EMR on the behavior of Wistar rats (196 males, 180-240 g of mass) under the conflict of opposed motivations: strong positive, drinking, motivation, and strong negative, pain, motivation were studied. The animals were exposed to low intensity EMR (40 microW/cm2) produced by two independent sources, 475 MHz (Albatross) with two orthogonal E vectors, and synchronization of rhythm modulation in the range of electroencephalography (EEG) frequency. The effect on behavior was observed during 10 min: 1) following the 5-minute exposure to EMR and 2) during the 10-minute exposure. Low intensity EMR of the above mentioned parameters and pulse modulation of 4, 8, 10 and 13 Hz was found to inhibit development of phobia to pain, increase the number of punishable contacts. It testifies to the existence of a weak anxiolytic effect which is similar to the effect of tranquilizers. If animals were exposed to EMR following administration of phenazepam, the radiation was shown to produce potentiation of the anxiolytic effect ofphenazepam. Effect of phenazepam is associated with activation ofbenzdiazipine receptors in the structure ofGABA-ergic receptor complex, which regulates neural membrane chloride channel conductance. We can suggest that anxiolytic and neurodepressive effects of EMR are realized to some extent at the level of ionophore and regulatory receptor complexes.
authors.forename: L N
authors.initials: LN
authors.lastname: Pavlov
authors.forename: B V
authors.initials: BV
authors.lastname: Dubrovik
authors.forename: l P
authors.initials: lP
authors.lastname: Zhavoronkov
authors.forename: V S
authors.initials: VS
authors.lastname: Glushakova
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects / Q000528:radiation effects*; D001569:Benzodiazepines / Q000008:administration & dosage; D060733:Electromagnetic Radiation; D008297:Male; D010146:Pain; D010698:Phobic Disorders; D051381:Rats; D017208:Rats, Wistar
chemical_list: D001569:Benzodiazepines; C017928:phenazepam