title: Prostate volume did not affect voiding function improvements in diode laser enucleation of the prostate.
abstract: OBJECTIVE
  We compared safety and surgical outcomes in patients with different prostate sizes treated with diode laser enucleation of the prostate.
  
  
  METHODS
  From 2008 to 2012 consecutive patients with benign prostatic obstruction undergoing diode laser prostate enucleation at our institution were enrolled for analysis. A single surgeon performed diode laser prostate enucleation with an end firing, continuous wave diode laser (980 nm). Based on preoperative prostate volume on transrectal ultrasound, patients were stratified into 2 groups, including group 1-65 with less than 60 ml and group 2-55 with 60 ml or greater. Baseline and perioperative characteristics, and postoperative surgical outcomes were compared between the 2 groups.
  
  
  RESULTS
  A total of 120 men with a mean ± SD age of 70.2 ± 9.0 years were enrolled for analysis. Compared with group 1 patients, those in group 2 had larger mean total prostate volume (85.0 ± 24.6 vs 40.9 ± 10.8 ml), longer mean operative time (117.7 ± 48.2 vs 60.7 ± 25.0 minutes), higher mean retrieved prostate weight (37.3 ± 16.1 vs 12.5 ± 7.3 gm) and a higher mean tissue retrieval ratio (74.4% ± 22.2% vs 58.8% ± 23.2%, p <0.01). There was no significant difference in the postoperative hemoglobin decrease in the 2 groups (median 0.5 vs 0.9 mg/dl, p = 0.11). The rate of temporary postoperative urinary retention after Foley catheter removal was significantly lower in group 2 (15.4% vs 3.6%, p = 0.04). Postoperative improvements in the peak flow rate, post-void residual urine volume and International Prostate Symptom Score were comparable in the 2 groups.
  
  
  CONCLUSIONS
  Although patients with a larger prostate required significantly longer operative time and laser energy, voiding function improvements and surgical complication rates of diode laser prostate enucleation were comparable in patients with a larger vs smaller prostate.
authors.affiliation: Division of Urology, Department of Surgery and Department of Pathology, Buddhist Tzu Chi General Hospital, Taipei Branch, New Taipei Taiwan.
authors.forename: Stephen Shei-Dei
authors.initials: SS
authors.lastname: Yang
authors.forename: Cheng-Hsing
authors.initials: CH
authors.lastname: Hsieh
authors.forename: I-Ni
authors.initials: IN
authors.lastname: Chiang
authors.forename: Chia-Da
authors.initials: CD
authors.lastname: Lin
authors.forename: Shang-Jen
authors.initials: SJ
authors.lastname: Chang
mesh_terms: D000368:Aged; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation*; D054023:Lasers, Semiconductor / Q000627:therapeutic use*; D008297:Male; D009929:Organ Size; D011379:Prognosis; D011467:Prostate / Q000000981:diagnostic imaging / Q000601:surgery*; D011470:Prostatic Hyperplasia / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D012189:Retrospective Studies; D020728:Transurethral Resection of Prostate / Q000379:methods*; D014463:Ultrasonography; D014555:Urination Disorders / Q000209:etiology / Q000503:physiopathology*; D014563:Urodynamics / Q000502:physiology*