title: A chelating tetrapeptide rhodium complex comprised of a histidylidene residue: biochemical tailoring of an NHC-Rh hydrosilylation catalyst.
abstract: Coupling of a histidinium salt with a MetAlaAla amino acid sequence followed by metallation with [RhCl(cod)](2) yields a rhodium(I) NHC complex with a pending peptide residue. Methionine chelation, induced by chloride abstraction from the metal coordination sphere, affords an efficient hydrosilylation catalyst precursor comprised of a peptidic macrocyclic chelate backbone.
authors.affiliation: School of Chemistry & Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.
authors.forename: Angèle
authors.initials: A
authors.lastname: Monney
authors.forename: Martin
authors.initials: M
authors.lastname: Albrecht
mesh_terms: D002384:Catalysis; D002614:Chelating Agents / Q000138:chemical synthesis / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006639:Histidine / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*
chemical_list: D002614:Chelating Agents; D006571:Heterocyclic Compounds; D012821:Silanes; C030011:carbene; D006639:Histidine; D012238:Rhodium; D008697:Methane