title: Caries-preventive effect of fissure sealant containing surface reaction-type pre-reacted glass ionomer filler and bonded by self-etching primer.
abstract: OBJECTIVE
  We aimed to evaluate the caries-preventive effect of a fissure sealant containing surface reaction-type pre-reacted glass ionomer (S-PRG) filler and bonded by self-etching primer versus those of 2 conventional resin-based sealants bonded by acid etching in terms of its impact on enamel demineralization and remineralization, enamel bond strength, and integrity of debonded enamel surfaces.
  
  
  METHODS
  Demineralization, remineralization, and bond strength on untreated enamel and enamel subsurface lesions of bovine incisors were assessed among the sealants by polarizing microscopy and microradiography; debonded enamel surfaces were examined by scanning electron microscopy.
  
  
  RESULTS
  The conventional resin-based sealants bonded by acid etching caused surface defects on the enamel subsurface lesions and significantly increased the lesion depth (p = 0.014), indicative of enamel demineralization. However the S-PRG filler-containing sealant bonded by self-etching primer maintained the enamel surface integrity and inhibited enamel demineralization. No difference in bond strength on both untreated enamel and enamel subsurface lesions was noted among the sealants.
  
  
  CONCLUSIONS
  An S-PRG filler-containing fissure sealant bonded by self-etching primer can prevent enamel demineralization, microleakage, and gaps without the tags created by acid etching regardless of the enamel condition. Such sealants are suitable for protecting the pits and fissures of immature permanent teeth.
authors.affiliation: Department of Pediatric Dentistry, School of Life Dentistry at Tokyo, Nippon Dental University, Japan. kisaki-s@tky.ndu.ac.jp
authors.forename: Kisaki
authors.initials: K
authors.lastname: Shimazu
authors.forename: Kiyokazu
authors.initials: K
authors.lastname: Ogata
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Karibe
mesh_terms: D000134:Acid Etching, Dental / Q000379:methods; D000180:Acrylic Resins / Q000737:chemistry / Q000627:therapeutic use*; D000818:Animals; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry / Q000627:therapeutic use; D002327:Cariostatic Agents / Q000627:therapeutic use*; D002417:Cattle; D001840:Dental Bonding / Q000379:methods*; D003731:Dental Caries / Q000517:prevention & control*; D003743:Dental Enamel / Q000187:drug effects / Q000648:ultrastructure; D003763:Dental Leakage / Q000145:classification; D003799:Dental Stress Analysis / Q000295:instrumentation; D005899:Glass Ionomer Cements / Q000737:chemistry / Q000627:therapeutic use*; D008422:Materials Testing; D008852:Microradiography; D008855:Microscopy, Electron, Scanning; D008859:Microscopy, Polarization; D010895:Pit and Fissure Sealants / Q000737:chemistry / Q000627:therapeutic use*; D019279:Resin Cements / Q000737:chemistry / Q000627:therapeutic use; D012822:Silicon Dioxide / Q000737:chemistry / Q000627:therapeutic use*; D013314:Stress, Mechanical; D017001:Tooth Demineralization / Q000517:prevention & control; D014089:Tooth Remineralization
chemical_list: D000180:Acrylic Resins; D002327:Cariostatic Agents; D005899:Glass Ionomer Cements; D010895:Pit and Fissure Sealants; D019279:Resin Cements; C015897:glass ionomer; C099291:teethmate-FTM; D017438:Bisphenol A-Glycidyl Methacrylate; D012822:Silicon Dioxide