title: Efficacy of a fish protein hydrolysate in malnourished children.
abstract: Protein hydrolysates are good nutritional supplements as their bioactive ingredients can be easily absorbed and utilized for various metabolic activities. A fish protein hydrolysate (Amizate), prepared by a unique process of hydrolysis has the advantage of high di/tri peptide content (<10 kDa) along with essential and non essential amino acids, micronutrients and vitamins. The effect of Amizate on malnourished children (6-8 years, a total of 438) of Grade I and II (Gomez's classification) with respect to immunoglobulins, CD4/CD8 ratios and hemoglobin was examined. Measurement of these parameters during the user trial study (at the beginning and the end after 4 months) indicated that the levels of the immunological parameters were not significantly altered by the Amizate treatment. The values of immunoglobulins and CD4/CD8 ratios of malnourished children (India) are in the normal range and are in accordance with the reported values of various ethnic groups.
  
  
  BACKGROUND
  The online version of this article (doi:10.1007/s12291-011-0145-z) contains supplementary material, which is available to authorized users.
authors.affiliation: Zymtech Production AS, Lesja, Norway.
authors.forename: Knut Olav
authors.initials: KO
authors.lastname: Nesse
authors.forename: A P
authors.initials: AP
authors.lastname: Nagalakshmi
authors.forename: P
authors.initials: P
authors.lastname: Marimuthu
authors.forename: Mamta
authors.initials: M
authors.lastname: Singh