title: Methyltrioxorhenium-catalyzed epoxidation of homoallylic alcohols with hydrogen peroxide.
abstract: Homoallylic alcohols were efficiently converted to the corresponding 3,4-epoxy alcohols in excellent yields by methyltrioxorhenium (MTO)-catalyzed epoxidation with aqueous hydrogen peroxide as the terminal oxidant and 3-methylpyrazole (10 mol %) as an additive. The epoxidations of homoallylic alcohols proceeded under organic solvent-free conditions faster than those in dichloromethane.
authors.affiliation: Toyama Industrial Technology Center, 150 Futagami, Takaoka, Toyama 933-0981, Japan. s-yamazk@itc.pref.toyama.jp
authors.forename: Shigekazu
authors.initials: S
authors.lastname: Yamazaki
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D004852:Epoxy Compounds / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011720:Pyrazoles / Q000737:chemistry*
chemical_list: D000438:Alcohols; D004852:Epoxy Compounds; D009942:Organometallic Compounds; D011720:Pyrazoles; C411866:methyltrioxorhenium VII; D006861:Hydrogen Peroxide