title: Artificial cytoskeletal structures within enzymatically active bio-inorganic protocells.
abstract: The fabrication of enzymatically active, semi-permeable bio-inorganic protocells capable of self-assembling a cytoskeletal-like interior and undergoing small-molecule dephosphorylation reactions is described. Reversible disassembly of an amino acid-derived supramolecular hydrogel within the internalized reaction space is used to tune the enzymatic activity of the nanoparticle-bounded inorganic compartments.
authors.affiliation: Centre for Organized Matter Chemistry, School of Chemistry, University of Bristol, Bristol, UK.
authors.forename: Ravinash Krishna
authors.initials: RK
authors.lastname: Kumar
authors.forename: Mei
authors.initials: M
authors.lastname: Li
authors.forename: Sam N
authors.initials: SN
authors.lastname: Olof
authors.forename: Avinash J
authors.initials: AJ
authors.lastname: Patil
authors.forename: Stephen
authors.initials: S
authors.lastname: Mann
mesh_terms: D058045:Artificial Cells / Q000737:chemistry*; D004798:Enzymes / Q000737:chemistry / Q000378:metabolism*; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*
chemical_list: D004798:Enzymes; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate