title: Minor effects of green tea catechin supplementation on cardiovascular risk markers in active older people: a randomized controlled trial.
abstract: OBJECTIVE
  Although previous studies have shown that consumption of green tea catechins (GTC) and walking might prevent development of cardiovascular disease (CVD), the effects of GTC supplementation on CVD risk in active older people are unknown.
  
  
  METHODS
  A total of 52 older adults (male/female 20/32, mean age 69.1 ± 5.9 years) participating in a pedometer-based walking program were randomly assigned to a GTC group with an intake of 630.9 mg GTC daily (n=26) or a control group (n=26) for 14 weeks. Cardiovascular risk markers were measured before and after this trial.
  
  
  RESULTS
  In the GTC group, values of the following markers were significantly reduced (P<0.05) from the beginning to the end of the trial: waist circumference (from 84.2 ± 8.4 to 82.2 ± 8.5 cm), hip circumference (from 95.1 ± 6.9 to 92.2 ± 6.3 cm), total cholesterol (from 233.0 ± 46.3 to 218.8 ± 42.3 mg/dL), low-density lipoprotein cholesterol (from 130.4 ± 36.2 to 119.1 ± 33.4 mg/dL) and low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (from 2.0 ± 1.7 to 1.7 ± 0.5); only hip circumference (from 95.6 ± 8.1 to 94.1 ± 7.6 cm) was significantly reduced (P<0.05) in the control group. No significant between-group differences were found for any parameter measured.
  
  
  CONCLUSIONS
  Although GTC might reduce cholesterol levels, the present randomized control trial suggests that GTC supplementation in active older participants did not significantly affect cardiovascular risk markers. Future studies should identify more effective combinations of GTC supplementation and physical activity.
authors.affiliation: Graduate School of Life and Medical Sciences, Doshisha University, Kyoto, Japan. ryoplusm@gmail.com
authors.forename: Ryo
authors.initials: R
authors.lastname: Miyazaki
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Kotani
authors.forename: Makoto
authors.initials: M
authors.lastname: Ayabe
authors.forename: Kokoro
authors.initials: K
authors.lastname: Tsuzaki
authors.forename: Junko
authors.initials: J
authors.lastname: Shimada
authors.forename: Naoki
authors.initials: N
authors.lastname: Sakane
authors.forename: Hideto
authors.initials: H
authors.lastname: Takase
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ichikawa
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Yonei
authors.forename: Kojiro
authors.initials: K
authors.lastname: Ishii
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D002318:Cardiovascular Diseases / Q000097:blood* / Q000503:physiopathology / Q000517:prevention & control; D002392:Catechin / Q000008:administration & dosage*; D008078:Cholesterol, LDL / Q000097:blood*; D019587:Dietary Supplements; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D013662:Tea; D013997:Time Factors; D016896:Treatment Outcome; D016138:Walking / Q000502:physiology*
chemical_list: D015415:Biomarkers; D008078:Cholesterol, LDL; D013662:Tea; D002392:Catechin