title: The emerging role of exercise and health counseling in patients with acute leukemia undergoing chemotherapy during outpatient management.
abstract: This study investigates the feasibility, safety and benefits of a 6-week exercise and health counseling intervention in patients with acute leukemia undergoing consolidation chemotherapy during outpatient management. Seventeen of twenty patients completed study requirements (85%), adherence to exercise was 73% and for health counseling 92%. There were improvements in the 6-min-walk-distance (p=0.0013), sit-to-stand test (p=0.0062), the right and left biceps arm-curl tests p=0.0002 and p=0.0002, respectively; health-related quality of life (p=0.0209) (FACT-An), vitality (p=0.0015), mental health (p=0.0471) and physical component scale (p=0.0295) (SF36). Significant reduction in the symptom burden (p=0.0021) and symptom interference on daily life activities (p=0.0069) (MDASI). No adverse reactions were observed.
authors.affiliation: Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. mary@ucsf.dk
authors.forename: Mary
authors.initials: M
authors.lastname: Jarden
authors.forename: Lis
authors.initials: L
authors.lastname: Adamsen
authors.forename: Lars
authors.initials: L
authors.lastname: Kjeldsen
authors.forename: Henrik
authors.initials: H
authors.lastname: Birgens
authors.forename: Anders
authors.initials: A
authors.lastname: Tolver
authors.forename: Jesper Frank
authors.initials: JF
authors.lastname: Christensen
authors.forename: Merete
authors.initials: M
authors.lastname: Stensen
authors.forename: Vivi-Ann
authors.initials: VA
authors.lastname: Sørensen
authors.forename: Tom
authors.initials: T
authors.lastname: Møller
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D037001:Directive Counseling; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D007938:Leukemia / Q000188:drug therapy / Q000628:therapy*; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D010045:Outpatients; D010865:Pilot Projects; D011788:Quality of Life; D057566:Self Report; D016896:Treatment Outcome; D055815:Young Adult