title: An efficient asymmetric biomimetic transamination of α-keto esters to chiral α-amino esters.
abstract: An efficient asymmetric biomimetic transamination of α-keto esters with quinine derivatives as chiral bases was described. A wide variety of α-amino esters containing various functional groups can be synthesized in high yield and enantioselectivity.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Xiao
authors.forename: Mao
authors.initials: M
authors.lastname: Liu
authors.forename: Chao
authors.initials: C
authors.lastname: Rong
authors.forename: Fazhen
authors.initials: F
authors.lastname: Xue
authors.forename: Songlei
authors.initials: S
authors.lastname: Li
authors.forename: Ying
authors.initials: Y
authors.lastname: Xie
authors.forename: Yian
authors.initials: Y
authors.lastname: Shi
mesh_terms: D000586:Amination; D032701:Biomimetics; D002384:Catalysis; D004952:Esters / Q000737:chemistry* / Q000378:metabolism; D006860:Hydrogen Bonding; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism; D000637:Transaminases / Q000378:metabolism
chemical_list: D004952:Esters; D000637:Transaminases