title: Characterization of a verocytotoxin-producing enteroaggregative Escherichia coli serogroup O111:H21 strain associated with a household outbreak in Northern Ireland.
abstract: A strain of Escherichia coli O111:H21 recently isolated in the United Kingdom harbored the phage-encoded vtx2c gene and the aggregative adherence plasmid. Although exhibiting the same pathogenic profile as the E. coli O104:H4 strain linked to the outbreak in Germany, there were important differences in strain characteristics and in the epidemiological setting.
authors.affiliation: Laboratory of Gastrointestinal Pathogens, Health Protection Agency, London, United Kingdom.
authors.forename: Tim
authors.initials: T
authors.lastname: Dallman
authors.forename: Geoffrey P
authors.initials: GP
authors.lastname: Smith
authors.forename: Brendan
authors.initials: B
authors.lastname: O'Brien
authors.forename: Marie A
authors.initials: MA
authors.lastname: Chattaway
authors.forename: David
authors.initials: D
authors.lastname: Finlay
authors.forename: Kathie A
authors.initials: KA
authors.lastname: Grant
authors.forename: Claire
authors.initials: C
authors.lastname: Jenkins
mesh_terms: D000818:Animals; D002675:Child, Preschool; D016000:Cluster Analysis; D003090:Coliphages / Q000235:genetics; D004196:Disease Outbreaks; D004926:Escherichia coli / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology; D005191:Family Characteristics; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D017720:Molecular Epidemiology; D058885:Multilocus Sequence Typing; D009660:Northern Ireland / Q000453:epidemiology; D010957:Plasmids; D039002:Prophages / Q000235:genetics; D012703:Serotyping; D022641:Shiga Toxin 2 / Q000235:genetics; D054323:Shiga-Toxigenic Escherichia coli / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*
chemical_list: D022641:Shiga Toxin 2