title: [Pregnancy-associated breast cancer: current opinions on diagnosis and treatment].
abstract: Because of the trend to postpone childbirth until later in life we will be increasingly confronted with pregnancy-associated breast cancer. We report on two patients with pregnancy-associated breast cancer. Complete treatment of this condition during pregnancy by means of surgery, radiotherapy and chemotherapy is possible without any known damage to the foetus, even if the breast cancer is diagnosed early in pregnancy. Treatment should be multidisciplinary and preferably centralized. Pregnancy does not seem to influence the prognosis of breast cancer. All patients with pregnancy-associated breast cancer should be registered in a registration study.
authors.affiliation: Afd. Klinische Oncologie, Leids Universitair Medisch Centrum, Leiden, the Netherlands. m.slingerland@lumc.nl
authors.forename: Marije
authors.initials: M
authors.lastname: Slingerland
authors.forename: Judith  R
authors.initials: J
authors.lastname: Kroep
authors.forename: Gerrit-Jan
authors.initials: GJ
authors.lastname: Liefers
authors.forename: Astrid  N
authors.initials: A
authors.lastname: Scholten
authors.forename: J W R Hans
authors.initials: JW
authors.lastname: Nortier
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D018270:Carcinoma, Ductal, Breast / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D000075202:Contraindications; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000628:therapy; D008207:Lymphatic Metastasis; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000628:therapy*; D011256:Pregnancy Outcome; D011379:Prognosis; D011878:Radiotherapy; D012307:Risk Factors; D016896:Treatment Outcome