title: Symptomatic chronic strongyloidiasis in children following treatment for solid organ malignancies: case reports and literature review.
abstract: Strongyloidiasis is an infection caused by the intestinal nematode Strongyloides   stercoralis. Infected healthy individuals are usually asymptomatic, however it is potentially   fatal in immunocompromised hosts due to its capacity to cause an overwhelming   hyperinfection. Strongyloidiasis could be missed during routine screening because of low and   intermittent larval output in stool and variable manifestations of the symptoms. We present   two cases of strongyloidiasis occurring in children with solid organ malignancies suspected   to have the infection based on their clinical conditions and treatment history for cancer. Both   patients were diagnosed by molecular and serological tests and were successfully treated.   Thus, strongyloidiasis in patients undergoing intensive treatment for malignancies should be   suspected, properly investigated and treated accordingly.
authors.affiliation: Department of Pediatric, Hospital Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan.
authors.forename: M
authors.initials: M
authors.lastname: Norsarwany
authors.forename: Z
authors.initials: Z
authors.lastname: Abdelrahman
authors.forename: N
authors.initials: N
authors.lastname: Rahmah
authors.forename: N
authors.initials: N
authors.lastname: Ariffin
authors.forename: A
authors.initials: A
authors.lastname: Norsyahida
authors.forename: B
authors.initials: B
authors.lastname: Madihah
authors.forename: M
authors.initials: M
authors.lastname: Zeehaida
mesh_terms: D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery; D002675:Child, Preschool; D003967:Diarrhea / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D004797:Enzyme-Linked Immunosorbent Assay; D005243:Feces / Q000469:parasitology; D018197:Hepatoblastoma / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D016867:Immunocompromised Host; D007814:Larva; D008113:Liver Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery; D008297:Male; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D011859:Radiography; D060888:Real-Time Polymerase Chain Reaction; D018335:Rhabdoid Tumor / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery; D017171:Strongyloides stercoralis / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D013322:Strongyloidiasis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology; D013724:Teratoma / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery
chemical_list: D000871:Anthelmintics; D015766:Albendazole