title: Staged hepatectomy for bilobar colorectal hepatic metastases.
abstract: OBJECTIVE
  This study describes the management of patients with bilobar colorectal liver metastases (CRLM).
  
  
  METHODS
  A retrospective collection of data on all patients with CRLM who were considered for staged resection (n= 85) from January 2003 to January 2011 was performed. Patients who underwent one hepatic resection were considered to have had a failed staged resection (FSR), whereas those who underwent a second or third hepatic resection to produce a cure were considered to have had a successful staged resection (SSR). Survival was calculated from the date of diagnosis of liver metastases. Complete follow-up and dates of death were obtained from the Government of Quebec population database.
  
  
  RESULTS
  Median survival was 46 months (range: 30-62 months) in the SSR group and 22 months (range: 19-29 months) in the FSR group. Rates of 5-year survival were 42% and 4% in the SSR and FSR groups, respectively. Fifteen of the 19 patients who remained alive at the last follow-up date belonged to the SSR group.
  
  
  CONCLUSIONS
  In patients in whom staged resection for bilobar CRLM is feasible, surgery would appear to offer benefit.
authors.affiliation: Hepatopancreatobiliary and Multi-Organ Transplant Surgery, McGill University Health Centre, Montreal, QC, Canada.
authors.forename: Mohammad H
authors.initials: MH
authors.lastname: Jamal
authors.forename: Mazen
authors.initials: M
authors.lastname: Hassanain
authors.forename: Prosanto
authors.initials: P
authors.lastname: Chaudhury
authors.forename: Tung T
authors.initials: TT
authors.lastname: Tran
authors.forename: Stephanie
authors.initials: S
authors.lastname: Wong
authors.forename: Yasmine
authors.initials: Y
authors.lastname: Yousef
authors.forename: Yelda
authors.initials: Y
authors.lastname: Jozaghi
authors.forename: Ayat
authors.initials: A
authors.lastname: Salman
authors.forename: Samir
authors.initials: S
authors.lastname: Jabbour
authors.forename: Eve
authors.initials: E
authors.lastname: Simoneau
authors.forename: Saleh
authors.initials: S
authors.lastname: Al-Abbad
authors.forename: Murad
authors.initials: M
authors.lastname: Al-Jiffry
authors.forename: Goffredo
authors.initials: G
authors.lastname: Arena
authors.forename: Petr
authors.initials: P
authors.lastname: Kavan
authors.forename: Peter
authors.initials: P
authors.lastname: Metrakos
mesh_terms: D000368:Aged; D016009:Chi-Square Distribution; D015179:Colorectal Neoplasms / Q000401:mortality / Q000473:pathology*; D018572:Disease-Free Survival; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D006801:Humans; D053208:Kaplan-Meier Estimate; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D011792:Quebec; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome