title: The neural effects of psychotropic medications in children and adolescents.
abstract: Little is known about the neurobiological effects of psychotropic medications used in the treatment of children and adolescents diagnosed with a psychiatric disorder. This review provides a synopsis of the literature demonstrating the neural effects associated with exposure to psychotropic medication in youth using multimodal neuroimaging. The article concludes by illustrating how, taken together, these studies suggest that pharmacological interventions during childhood do indeed affect brain structure and function in a detectable manner, and the effects appear to be ameliorative.
authors.affiliation: Division of Child and Adolescent Psychiatry, Stanford University School of Medicine, Stanford, CA 94305-5719, USA. mksingh@stanford.edu
authors.forename: Manpreet K
authors.initials: MK
authors.lastname: Singh
authors.forename: Kiki D
authors.initials: KD
authors.lastname: Chang
mesh_terms: D000293:Adolescent; D000856:Anorexia Nervosa / Q000188:drug therapy / Q000503:physiopathology; D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy / Q000503:physiopathology; D001714:Bipolar Disorder / Q000188:drug therapy / Q000503:physiopathology; D001921:Brain / Q000187:drug effects* / Q000503:physiopathology; D002648:Child; D006801:Humans; D008279:Magnetic Resonance Imaging; D001523:Mental Disorders / Q000188:drug therapy / Q000503:physiopathology*; D059906:Neuroimaging; D011619:Psychotropic Drugs / Q000494:pharmacology* / Q000627:therapeutic use; D019265:Spectroscopy, Near-Infrared
chemical_list: D011619:Psychotropic Drugs