title: Elliptical subject-specific model of respiratory motion for cardiac MRI.
abstract: Respiratory motion is a major problem in cardiac MRI. In this work, the displacement of the heart relative to the diaphragm was investigated. A subject-specific nonlinear elliptical affine model has been developed to incorporate the effect of hysteresis in motion correction. Nine healthy volunteers participated in a study in which the diaphragm position and an image of the heart were acquired during each cardiac cycle, while breathing freely. The elliptical model was compared to a linear affine model, and the results show that the elliptical model performed significantly (P < 0.05) better than the linear model. Further, it has been established that the model can be constructed from 25 s of prescan data, which makes it feasible to perform a short prescan to construct the model, so that subject-specific prospective motion correction of the heart can be integrated into structural cardiac MRI sequences.
authors.affiliation: MRC/UCT Medical Imaging Research Unit, Department of Human Biology, University of Cape Town, South Africa.
authors.forename: Ian
authors.initials: I
authors.lastname: Burger
authors.forename: Ernesta M
authors.initials: EM
authors.lastname: Meintjes
mesh_terms: D000328:Adult; D006321:Heart; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D008962:Models, Theoretical; D012119:Respiration