title: Direct Pd-catalyzed cross-coupling of functionalized organoaluminum reagents.
abstract: A handsome couple: Through the use of the simple Pd catalyst [Pd(tmpp)(2)Cl(2)] (tmpp = tris(2,4,6-trimethoxyphenyl)phosphine) and THF/DMF as solvent, various aryl-, heteroaryl-, benzyl- and alkylaluminum reagents can be readily cross-coupled with aryl or heteroaryl iodides, bromides, and nonaflates, and in special cases even with chlorides and triflates. This cross-coupling tolerates free NH(2) groups, aldehydes, ketones, esters, and nitro functions.
authors.affiliation: Department Chemie, Ludwig Maximilians-Universität München, Butenandtstrasse 5-13, Haus F, 81377 München, Germany.
authors.forename: Klaus
authors.initials: K
authors.lastname: Groll
authors.forename: Tobias D
authors.initials: TD
authors.lastname: Blümke
authors.forename: Andreas
authors.initials: A
authors.lastname: Unsinn
authors.forename: Diana
authors.initials: D
authors.lastname: Haas
authors.forename: Paul
authors.initials: P
authors.lastname: Knochel
mesh_terms: D000535:Aluminum / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D010165:Palladium; D000535:Aluminum