title: Risk for contrast-induced nephropathy in elderly trauma patients.
abstract: The objective of this study was to determine if elderly trauma patients are at risk for contrast-induced nephropathy (CIN). A retrospective study was conducted identifying 362 patients 65 years and older in our Level I trauma center who received computerized tomography (CT) scans with  intravenous contrast. CIN was defined as a 25 per cent increase in serum creatinine levels or a 0.5 mg/dL increase above baseline after CT. History of diabetes mellitus, hospital length of stay, intensive care unit length of stay, Injury Severity Score (ISS), and age were recorded. Eighteen  per cent (21 of 118) of the patients had a peak in creatinine, 12 per cent (14 of 118) peaked and returned to baseline, and 6 per cent (7 of 118) peaked and stayed high. Pre-CT elevated creatinine, diabetes mellitus, increased hospital length of stay, ISS, and age show little association to  CIN. The data suggest that CIN in elderly trauma patients is rare, regardless of history of diabetes mellitus, age, creatinine, high ISS, or result in higher length of stay. Therefore, there is little justification for the delay in diagnosis to assess a patient's renal susceptibility.
authors.affiliation: University of California-Irvine Medical Center, Orange, California 92868, USA. rfinigan@uci.edu
authors.forename: Ryan
authors.initials: R
authors.lastname: Finigan
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Pham
authors.forename: Rosemarie
authors.initials: R
authors.lastname: Mendoza
authors.forename: Michael
authors.initials: M
authors.lastname: Lekawa
authors.forename: Matthew
authors.initials: M
authors.lastname: Dolich
authors.forename: Allen
authors.initials: A
authors.lastname: Kong
authors.forename: Nicole
authors.initials: N
authors.lastname: Bernal
authors.forename: Stephanie
authors.initials: S
authors.lastname: Lush
authors.forename: Cristobal
authors.initials: C
authors.lastname: Barrios
mesh_terms: D000368:Aged; D003287:Contrast Media / Q000009:adverse effects*; D003404:Creatinine / Q000097:blood; D006801:Humans; D007674:Kidney Diseases / Q000097:blood / Q000139:chemically induced*; D012189:Retrospective Studies; D012307:Risk Factors; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D003404:Creatinine