title: Influence of the variation of the alkyl chain length of N-alkyl-β-D-glycosylamine derivatives on antifungal properties.
abstract: Twelve new glucosidic and galactosidic derivatives of N-alkylaminosugars with different alkylamines from 6 to 18 carbons were synthesized and characterized by (1)H and (13)C NMR. Their antifungal activity against the food fungal pathogen  Aspergillus niger  was evaluated using the radial growth assay. The influence of the variation of the alkyl chain length of N-alkylaminosugars on the mycelium growth was then discussed. Inhibition by the different alkylamines is shown as a biostatic effect rather than a biocidal effect. It was observed that alkylamines keep their antifungal properties after a thermal treatment compatible with food packaging and processing.
authors.affiliation: Laboratoire de Chimie des Polymères Organiques (LCPO), University of Bordeaux, UMR 5629, F-33600 Pessac, France.
authors.forename: Virginie
authors.initials: V
authors.lastname: Neto
authors.forename: Aurélien
authors.initials: A
authors.lastname: Voisin
authors.forename: Valérie
authors.initials: V
authors.lastname: Héroguez
authors.forename: Stéphane
authors.initials: S
authors.lastname: Grelier
authors.forename: Véronique
authors.initials: V
authors.lastname: Coma
mesh_terms: D000588:Amines / Q000737:chemistry / Q000494:pharmacology*; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy
chemical_list: D000588:Amines; D000935:Antifungal Agents