title: Mapping mechanical properties of organic thin films by force-modulation microscopy in aqueous media.
abstract: The mechanical properties of organic and biomolecular thin films on surfaces play an important role in a broad range of applications. Although force-modulation microscopy (FMM) is used to map the apparent elastic properties of such films with high lateral resolution in air, it has rarely been applied in aqueous media. In this letter we describe the use of FMM to map the apparent elastic properties of self-assembled monolayers and end-tethered protein thin films in aqueous media. Furthermore, we describe a simple analysis of the contact mechanics that enables the selection of FMM imaging parameters and thus yields a reliable interpretation of the FMM image contrast.
authors.affiliation: Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, USA ; Center for Biologically Inspired Materials and Materials Systems, Duke University, Durham, North Carolina 27708, USA.
authors.forename: Jianming
authors.initials: J
authors.lastname: Zhang
authors.forename: Zehra
authors.initials: Z
authors.lastname: Parlak
authors.forename: Carleen M
authors.initials: CM
authors.lastname: Bowers
authors.forename: Terrence
authors.initials: T
authors.lastname: Oas
authors.forename: Stefan
authors.initials: S
authors.lastname: Zauscher