title: Pathophysiology of migraine.
abstract: Migraine is a common disabling brain disorder whose pathophysiology is now being better understood. The study of anatomy and physiology of pain producing structures in the cranium and the central nervous system modulation of the input have led to the conclusion that migraine involves alterations in the sub-cortical aminergic sensory modulatory systems that influence the brain widely.
authors.affiliation: Headache Group, Department of Neurology, University of California, San Francisco, CA, USA.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Goadsby