title: Antioxidant phenolic glycosides from the roots of Illicium dunnianum.
abstract: Eight new phenolic glycosides, dunnianosides A-H (1-8), and nine known phenolic glycosides (9-17), were isolated from the roots of Illicium dunnianum. The structures of these new compounds were elucidated by spectroscopic methods including 1D and 2D NMR, HRESIMS, and chemical methods. Compounds 1-5, 7, and 9 exhibited potent antioxidant activities against Fe(2+)-cystine-induced rat liver microsomal lipid peroxidation, with IC(50) values ranging from 3.8 ± 0.6 to 23.0 ± 2.2 μM.
authors.affiliation: State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People's Republic of China.
authors.forename: Jian
authors.initials: J
authors.lastname: Bai
authors.forename: Zhen-Feng
authors.initials: ZF
authors.lastname: Fang
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
authors.forename: Shi-Shan
authors.initials: SS
authors.lastname: Yu
authors.forename: Dan
authors.initials: D
authors.lastname: Zhang
authors.forename: Huai-Ling
authors.initials: HL
authors.lastname: Wei
authors.forename: Shuang-Gang
authors.initials: SG
authors.lastname: Ma
authors.forename: Yong
authors.initials: Y
authors.lastname: Li
authors.forename: Jing
authors.initials: J
authors.lastname: Qu
authors.forename: Song
authors.initials: S
authors.lastname: Xu
authors.forename: Jing-Hong
authors.initials: JH
authors.lastname: Ren
authors.forename: Fen
authors.initials: F
authors.lastname: Zhao
authors.forename: Nan
authors.initials: N
authors.lastname: Zhao
authors.forename: Jun-Hong
authors.initials: JH
authors.lastname: Liu
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D029523:Illicium / Q000737:chemistry*; D008968:Molecular Conformation; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification*; D018517:Plant Roots / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D006027:Glycosides; D010636:Phenols