title: Forensic evaluation of 11 non-standard STR loci in Bangladeshi population.
abstract: Allele frequencies and forensic efficiency parameters of 11 non-standard autosomal STR loci, D21S1437, D22S683, D8S1110, D10S2325, D12S1090, D17S1294, D3S1744, D14S608, D20S470, D18S536 and D13S765 were evaluated in a sample of 102 unrelated Bangladeshi individuals. No significant deviation from Hardy-Weinberg equilibrium was observed in any of the loci studied. Statistical parameters of forensic importance, the power of discrimination (PD), observed and expected heterozygosity (H), polymorphism information content (PIC), matching probability (MP), power of exclusion (PE) and typical paternity index (TPI) were calculated for the loci. The most informative locus among the 11 STR loci was D10S2325 (PD=0.958), while the least informative was D17S129 (PD=0.876). The combined PD (1-PM) and MP was calculated to be 0.9999999999997 and 2.23×10(-23), respectively. These parameters indicated the usefulness of the loci in forensic personal identification and parentage testing among Bangladeshi population.
authors.affiliation: Department of Biochemistry & Molecular Biology, University of Dhaka, Dhaka 1000, Bangladesh. sharif_akhteruzzaman@yahoo.com
authors.forename: Sharif
authors.initials: S
authors.lastname: Akhteruzzaman
authors.forename: Ahmad
authors.initials: A
authors.lastname: Ferdous
authors.forename: Pilu
authors.initials: P
authors.lastname: Momtaz
authors.forename: Rebeka
authors.initials: R
authors.lastname: Sultana
mesh_terms: D001459:Bangladesh; D016172:DNA Fingerprinting; D005787:Gene Frequency; D005828:Genetics, Population; D006579:Heterozygote; D006801:Humans; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction