title: Characterization of materials for optimal near-infrared and x-ray imaging of the breast.
abstract: Development of a detector case for complete co-registration of images in a non-fiber-based combined near-infrared spectral tomography and digital breast tomosynthesis, required analysis to find materials that could support a breast under full mammographic compression without affecting the x-ray images or the quality of the near infrared measurements. Several possible solutions were considered, and many types of plastics were tested in the development of the detector case. Light channeling within the detector case changed the data obtained in resin and agarose phantoms, lowering recovered absorption values. Additional developments focusing on blocking stray light were successful and permitted a normal subject imaging exam.
authors.affiliation: Thayer School of Engineering, Dartmouth College, Hanover, NH 03755,  USA.
authors.forename: Kelly
authors.initials: K
authors.lastname: Michaelsen
authors.forename: Venkataramanan
authors.initials: V
authors.lastname: Krishnaswamy
authors.forename: Brian W
authors.initials: BW
authors.lastname: Pogue
authors.forename: Ken
authors.initials: K
authors.lastname: Brooks
authors.forename: Ken
authors.initials: K
authors.lastname: Defreitas
authors.forename: Ian
authors.initials: I
authors.lastname: Shaw
authors.forename: Steven P
authors.initials: SP
authors.lastname: Poplack
authors.forename: Keith D
authors.initials: KD
authors.lastname: Paulsen