title: Labial ecthyma gangrenosum in an immunocompromised infant with leukemia: heightening awareness for the urologist.
abstract: Ecthyma gangrenosum (EG) is a cutaneous infection most commonly associated with Pseudomonas aeruginosa sepsis. EG generally occurs in immunocompromised hosts, such as patients with severe neutropenia. EG presents as erythematous, hemorrhagic, or necrotic macules or plaques, most commonly in the perineal or gluteal areas, but can occur elsewhere. EG is a dermatologic emergency in immunocompromised patients and should be included in the differential diagnosis when urologists are asked to evaluate perineal lesions. We describe the case of a highly immunocompromised infant with labial EG to highlight the importance of prompt clinical diagnosis and of multidisciplinary medical and surgical management.
authors.affiliation: Perelman School of Medicine, the University of Pennsylvania, Pennsylvania, USA.
authors.forename: Jose
authors.initials: J
authors.lastname: Pulido
authors.forename: Patrick
authors.initials: P
authors.lastname: McMahon
authors.forename: James R
authors.initials: JR
authors.lastname: Treat
authors.forename: John
authors.initials: J
authors.lastname: Gunselman
authors.forename: Gregory E
authors.initials: GE
authors.lastname: Tasian
authors.forename: Sarah K
authors.initials: SK
authors.lastname: Tasian
mesh_terms: D015897:Comorbidity; D003937:Diagnosis, Differential; D004473:Ecthyma / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D005260:Female; D005831:Genital Diseases, Female / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology*; D006801:Humans; D016867:Immunocompromised Host; D007223:Infant; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000453:epidemiology*; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000276:immunology*; D014572:Urology