title: Patent ductus arteriosus associated with pulmonary hypertension and desaturation.
abstract: We present the cases of three children with patent ductus arteriosus (PDA), pulmonary arterial hypertension (PAH), and desaturation. One of them had desaturation associated with atrial septal defect (ASD). His ASD, PAH, and desaturation improved after successful device closure of the PDA. The other two had desaturation associated with Down syndrome. One had desaturation only at room air oxygen (21% oxygen) but well saturated with 100% oxygen, subsequently underwent successful device closure of the PDA. The other had experienced desaturation at a younger age but spontaneously recovered when he was older, following attempted device closure of the PDA, with late embolization of the device.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. khositseth@gmail.com
authors.forename: Anant
authors.initials: A
authors.lastname: Khositseth
authors.forename: Suthep
authors.initials: S
authors.lastname: Wanitkun
mesh_terms: D000293:Adolescent; D001027:Aortography; D062186:Arterial Pressure; D006328:Cardiac Catheterization / Q000295:instrumentation; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000150:complications; D004374:Ductus Arteriosus, Patent / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D065627:Familial Primary Pulmonary Hypertension; D006344:Heart Septal Defects, Atrial / Q000150:complications; D006801:Humans; D006976:Hypertension, Pulmonary / Q000097:blood / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D010100:Oxygen / Q000097:blood*; D011652:Pulmonary Circulation; D055989:Septal Occluder Device; D016896:Treatment Outcome; D014655:Vascular Resistance
chemical_list: D010100:Oxygen