title: Toxic megacolon associated with cytomegalovirus infection in a patient with steroid-naïve ulcerative colitis.
abstract: Most cases of cytomegalovirus (CMV) colitis in patients with inflammatory bowel disease (IBD) occur in those treated with immunosuppressants and/or corticosteroids. We herein present the case of a 57-year-old man with toxic megacolon associated with CMV colitis in corticosteroid-naïve ulcerative colitis (UC). To date, there have been only eight previous case reports of CMV colitis in steroid-naïve UC. We discuss the need to consider CMV colitis when making a differential diagnosis of patients with refractory UC who are not receiving corticosteroid treatment.
authors.affiliation: Department of Gastroenterology and Hepatology, Kyoto Prefectural Yosanoumi Hospital, Japan. keninoue71@koto.kpu-m.ac.jp
authors.forename: Ken
authors.initials: K
authors.lastname: Inoue
authors.forename: Naoki
authors.initials: N
authors.lastname: Wakabayashi
authors.forename: Kohei
authors.initials: K
authors.lastname: Fukumoto
authors.forename: Shinya
authors.initials: S
authors.lastname: Yamada
authors.forename: Nobukatsu
authors.initials: N
authors.lastname: Bito
authors.forename: Naohisa
authors.initials: N
authors.lastname: Yoshida
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Katada
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Uchiyama
authors.forename: Takeshi
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Osamu
authors.initials: O
authors.lastname: Handa
authors.forename: Tomohisa
authors.initials: T
authors.lastname: Takagi
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Konishi
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Yagi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kokura
authors.forename: Mitsuo
authors.initials: M
authors.lastname: Kishimoto
authors.forename: Akio
authors.initials: A
authors.lastname: Yanagisawa
authors.forename: Yuji
authors.initials: Y
authors.lastname: Naito
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D003113:Colonoscopy; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D003937:Diagnosis, Differential; D015774:Ganciclovir / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008532:Megacolon, Toxic / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged
chemical_list: D000305:Adrenal Cortex Hormones; D000998:Antiviral Agents; D007166:Immunosuppressive Agents; D015774:Ganciclovir