title: Supramolecular metal displacement allows on-fluorescence analysis of manganese(II) in living cells.
abstract: Due to the importance of Mn(2+) ions in biological processes, it is of growing interest to develop protocols for analysis of Mn(2+) uptake and distribution in cells. A supramolecular metal displacement assay can provide ratiometric fluorescence detection of Mn(2+), allowing for quantitative and longitudinal analysis of Mn(2+) uptake in living cells.
authors.affiliation: Department of Chemistry, New York University, New York, NY 10003, USA.
authors.forename: Francesca
authors.initials: F
authors.lastname: Gruppi
authors.forename: Jian
authors.initials: J
authors.lastname: Liang
authors.forename: Benjamin B
authors.initials: BB
authors.lastname: Bartelle
authors.forename: Maksim
authors.initials: M
authors.lastname: Royzen
authors.forename: Daniel H
authors.initials: DH
authors.lastname: Turnbull
authors.forename: James W
authors.initials: JW
authors.lastname: Canary
mesh_terms: D002104:Cadmium / Q000737:chemistry*; D002460:Cell Line; D002470:Cell Survival; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D057809:HEK293 Cells; D006801:Humans; D046911:Macromolecular Substances / Q000737:chemistry; D008274:Magnesium / Q000032:analysis* / Q000493:pharmacokinetics
chemical_list: D005456:Fluorescent Dyes; D046911:Macromolecular Substances; D002104:Cadmium; D008274:Magnesium