title: Reproducibility of peroneal motor nerve conduction measurement in older adults.
abstract: OBJECTIVE
  While neuropathy is common in the elderly, nerve conduction (NC) reproducibility in older adults is not well-established. We sought to evaluate intraobserver reproducibility of peroneal motor NC measures in a diverse sample of older adults.
  
  
  METHODS
  We measured peroneal motor NC amplitude and velocity in a subset of participants (mean age=82.9±2.7, n=62, 50% female, 51.6% black, 35.5% DM) in the Health, Aging, and Body Composition Study. Using coefficients of variation (CVs), intraclass correlation coefficients (ICCs), and Bland Altman Plots, we compared two sets of measurements taken by the same examiner hours apart on the same day.
  
  
  RESULTS
  Low CVs (2.15-4.24%) and moderate to high ICCs (0.75-0.99) were observed. No systematic variation was found across measures. Despite small numbers in some subgroups, we found no differences in reproducibility by diabetes, race or study site.
  
  
  CONCLUSIONS
  NC measures have moderate to high intraobsever reproducibility in older adults and are not affected by diabetes, race, or gender.
  
  
  CONCLUSIONS
  These data provide evidence to support use of these measures in aging research.
authors.affiliation: Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, United States.
authors.forename: Rachel E
authors.initials: RE
authors.lastname: Ward
authors.forename: Robert M
authors.initials: RM
authors.lastname: Boudreau
authors.forename: Aaron I
authors.initials: AI
authors.lastname: Vinik
authors.forename: Sasa A
authors.initials: SA
authors.lastname: Zivkovic
authors.forename: Omer T
authors.initials: OT
authors.lastname: Njajou
authors.forename: Suzanne
authors.initials: S
authors.lastname: Satterfield
authors.forename: Tamara B
authors.initials: TB
authors.lastname: Harris
authors.forename: Anne B
authors.initials: AB
authors.lastname: Newman
authors.forename: Elsa S
authors.initials: ES
authors.lastname: Strotmeyer
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D001823:Body Composition; D005260:Female; D006801:Humans; D008297:Male; D009046:Motor Neurons / Q000502:physiology; D009431:Neural Conduction / Q000502:physiology*; D010543:Peroneal Nerve / Q000502:physiology*; D011446:Prospective Studies; D015203:Reproducibility of Results