title: Overview of protein glutathionylation.
abstract: Many proteins contain free thiols that can be modified by the reversible formation of mixed disulfides with glutathione. Protein glutathionylation is of significance for defense against oxidative damage and in redox signaling. Here we outline the mechanisms and possible significance of protein glutathionylation.
authors.affiliation: Medical Research Council, Dunn Human Nutrition Unit, Cambridge, United Kingdom.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Filipovska
authors.forename: Michael P
authors.initials: MP
authors.lastname: Murphy
mesh_terms: D054477:Glutaredoxins / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism*; D009569:Nitric Oxide / Q000378:metabolism; D010084:Oxidation-Reduction; D011506:Proteins / Q000378:metabolism*; D013438:Sulfhydryl Compounds / Q000378:metabolism; D013879:Thioredoxins / Q000378:metabolism
chemical_list: D054477:Glutaredoxins; D011506:Proteins; D013438:Sulfhydryl Compounds; D009569:Nitric Oxide; D013879:Thioredoxins; D005978:Glutathione