title: A case of idiopathic granulomatous hypophysitis.
abstract: Granulomatous hypophysitis is a rare pituitary condition that commonly presents with enlargement of the pituitary gland. A 31-year-old woman was admitted to the hospital with a severe headache and bitemporal hemianopsia. Magnetic resonance imaging (MRI) showed an 18 × 10-mm sellar mass with suprasellar extension and compression of the optic chiasm. Interestingly, brain MRI had shown no abnormal finding 4 months previously. On hormonal examination, hypopituitarism with mild hyperprolactinemia was noted. The biopsy revealed granulomatous changes with multinucleated giant cells. We herein report this rare case and discuss the relevant literature.
authors.affiliation: Department of Internal Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
authors.forename: Chul Ho
authors.initials: CH
authors.lastname: Chung
authors.forename: Min Soo
authors.initials: MS
authors.lastname: Song
authors.forename: Hyun Deuk
authors.initials: HD
authors.lastname: Cho
authors.forename: Du Shin
authors.initials: du S
authors.lastname: Jeong
authors.forename: Yeo Joo
authors.initials: YJ
authors.lastname: Kim
authors.forename: Hack Gun
authors.initials: HG
authors.lastname: Bae
authors.forename: Sang Jin
authors.initials: SJ
authors.lastname: Kim
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D015726:Giant Cells / Q000473:pathology; D006099:Granuloma / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006261:Headache / Q000209:etiology; D006423:Hemianopsia / Q000209:etiology; D006801:Humans; D006966:Hyperprolactinemia / Q000209:etiology; D007018:Hypopituitarism / Q000209:etiology; D007249:Inflammation / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008279:Magnetic Resonance Imaging; D009897:Optic Chiasm / Q000473:pathology; D010900:Pituitary Diseases / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D010901:Pituitary Function Tests; D010902:Pituitary Gland / Q000473:pathology* / Q000601:surgery; D011237:Predictive Value of Tests; D012720:Severity of Illness Index; D016896:Treatment Outcome