title: Is MRI a useful tool to distinguish between serous and mucinous borderline ovarian tumours?
abstract: OBJECTIVE
  To analyse the morphological magnetic resonance imaging (MRI) features of borderline ovarian tumours (BOT) and to evaluate whether MRI can be used to distinguish serous from mucinous subtypes.
  
  
  METHODS
  A retrospective study of 72 patients who underwent BOT resection was undertaken. MRI images were reviewed blindly by two radiologists to assess MRI features: size, tumour type, grouped and irregular thickened septa, number of septa, loculi of different signal intensity, vegetations, solid portion, signal intensity of vegetations, normal ovarian parenchyma, and pelvic ascites. Statistical analysis was performed using Mann-Whitney and Fisher's exact tests. Logistic regression analysis was used to assess the predictive value of the MRI findings for histological subtypes.
  
  
  RESULTS
  At histology, there were 33 serous BOT (SBOT) and 39 mucinous BOT (MBOT). Predictive MRI criteria for SBOT were bilaterality, predominantly solid tumour, and the presence of vegetations, especially exophytic or with a high T2 signal (p < 0.01), whereas predictive MRI criteria for MBOT were multilocularity, number of septa, loculi of different signal intensity, and grouped and irregular thickened septa (p < 0.01). Using multivariate analysis, vegetations were independently associated with SBOT [odds ratio (OR) = 29.5] and multilocularity with MBOT (OR = 3.9).
  
  
  CONCLUSIONS
  Vegetations and multilocularity are two independent MRI features that can help to distinguish between SBOT and MBOT.
authors.affiliation: Department of Radiology, Hôpital Tenon, Paris, France. marc.bazot@tnn.aphp.fr
authors.forename: M
authors.initials: M
authors.lastname: Bazot
authors.forename: D
authors.initials: D
authors.lastname: Haouy
authors.forename: E
authors.initials: E
authors.lastname: Daraï
authors.forename: A
authors.initials: A
authors.lastname: Cortez
authors.forename: S
authors.initials: S
authors.lastname: Dechoux-Vodovar
authors.forename: I
authors.initials: I
authors.lastname: Thomassin-Naggara
mesh_terms: D000328:Adult; D018282:Cystadenocarcinoma, Mucinous / Q000175:diagnosis* / Q000473:pathology; D018284:Cystadenocarcinoma, Serous / Q000175:diagnosis* / Q000473:pathology; D062625:Cystadenofibroma / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D047368:Tumor Burden; D055815:Young Adult