title: [Kidney and thyroid dysfunction].
abstract: Thyroid hormones influence renal development, kidney structure, renal hemodynamics, glomerular filtration rate, the function of many transport systems along the nephron, and sodium and water homeostasis. Effects of hypothyroidism and hyperthyroidism on kidney function are the result of direct renal effects, as well as systemic hemodynamic, metabolic, and cardiovascular effects. Most of the renal manifestations of thyroid disorders, which are clinically most significant with hypothyroidism, are reversible with treatment. Patients with hypothyroidism can have clinically important reductions in GFR, so screening for hypothyroidism should be considered in patients with unexplained elevations in serum creatinine. Patients with thyroid disorders are also at risk for immune-mediated glomerular diseases. Finally, patients with nephrotic syndrome, as well as acute and chronic kidney injury, have alterations in thyroid gland physiology that can impact thyroid function and the testing of thyroid function status. Dialysis patients have frequently hypothyroidism whose biological diagnosis must be careful.
authors.affiliation: Service de néphrologie, hôpital de Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, 75013 Paris, France.
authors.forename: Matthieu
authors.initials: M
authors.lastname: Ponsoye
authors.affiliation: Service de néphrologie, hôpital de Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, 75013 Paris, France.
authors.forename: Romain
authors.initials: R
authors.lastname: Paule
authors.affiliation: Service de néphrologie, hôpital de Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, 75013 Paris, France.
authors.forename: Victor
authors.initials: V
authors.lastname: Gueutin
authors.affiliation: Service de néphrologie, hôpital de Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, 75013 Paris, France.
authors.forename: Gilbert
authors.initials: G
authors.lastname: Deray
authors.affiliation: Service de néphrologie, hôpital de Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, 75013 Paris, France. Electronic address: hassan.izzedine@psl.aphp.fr.
authors.forename: Hassane
authors.initials: H
authors.lastname: Izzedine
mesh_terms: D006801:Humans; D006980:Hyperthyroidism / Q000150:complications* / Q000503:physiopathology; D007037:Hypothyroidism / Q000150:complications* / Q000503:physiopathology; D007674:Kidney Diseases / Q000209:etiology*; D013963:Thyroid Hormones / Q000502:physiology
chemical_list: D013963:Thyroid Hormones