title: Lymph node harvest in emergent versus elective colon resections.
abstract: Quality measures for prognostication of colon cancer include the removal of 12 or more lymph nodes during colon resection. The purpose of this study was to determine whether emergent surgery is associated with inadequate lymph node harvest. The National Cancer Database (NCDB) was queried for colon cancer patients operated on at Huntington Memorial Hospital, Pasadena, California, from 2005 to 2010. Demographic data, indication for surgery, surgeon, stage, lymph node harvest, tumor location, method of surgery, chemotherapy use, and survival were recorded. Univariate analyses were performed to compare lymph node harvest with the variables listed. Three hundred fifty-three patients underwent colon resection between 2005 and 2010. Two hundred ninety-six patients with Stage I to III disease underwent 253 elective (85%) and 43 emergent (15%) colectomies. There was no statistical difference between rates of adequate lymph node harvest in emergent and elective patient groups (86.0 vs 88.1%, P=0.7). Inferior long-term survival was associated with emergent indication and inferior lymph node harvest. Lymph node harvest adequacy showed a gradual increase over time from 79.5 per cent in 2005 to 95.5 per cent in 2010. Despite a perception that emergent surgery is associated with inadequate lymphadenectomy, 5-year data from Huntington Memorial Hospital participation in NCDB does not suggest inferior lymph node harvests in patients operated on for obstruction or perforation.
authors.affiliation: Huntington Hospital, Pasadena, California 91105, USA.
authors.forename: Aaron
authors.initials: A
authors.lastname: Lewis
authors.forename: Gabriel
authors.initials: G
authors.lastname: Akopian
authors.forename: Sharon
authors.initials: S
authors.lastname: Carillo
authors.forename: Howard S
authors.initials: HS
authors.lastname: Kaufman
mesh_terms: D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology / Q000601:surgery*; D017558:Elective Surgical Procedures; D004638:Emergency Treatment; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000592:standards*; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging; D012189:Retrospective Studies