title: Whole-body diffusion magnetic resonance imaging in the assessment of lymphoma.
abstract: The current evidence regarding the usefulness of whole-body diffusion-weighted magnetic resonance imaging (diffusion MRI) in the assessment of lymphoma is reviewed. Diffusion MRI combining both anatomical and bio-physiological information is currently under investigation as a valuable tool in the oncology field including lymphoma, not only for staging but also for the assessment of response. Representative images for each purpose are shown. Diffusion MRI requires no administration of contrast medium and does not use ionizing radiation, which could be particularly advantageous for repeat follow-up surveillance in lymphoma patients. Diffusion MRI may prove to be a useful biomarker in clinical decision making for patients with lymphoma. Large-scale prospective studies are warranted to further establish its complementary value to the current standard of care, [(18)F]fluorodeoxyglucose positron emission tomography/computed tomography.
authors.affiliation: Department of Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial Hospital and Chang Gung University, Gueishan, Taoyuan, Taiwan.
authors.forename: Chieh
authors.initials: C
authors.lastname: Lin
authors.forename: Alain
authors.initials: A
authors.lastname: Luciani
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Itti
authors.forename: Corinne
authors.initials: C
authors.lastname: Haioun
authors.forename: Violaine
authors.initials: V
authors.lastname: Safar
authors.forename: Michel
authors.initials: M
authors.lastname: Meignan
authors.forename: Alain
authors.initials: A
authors.lastname: Rahmouni
mesh_terms: D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D006801:Humans; D008207:Lymphatic Metastasis; D008223:Lymphoma / Q000473:pathology*; D064847:Multimodal Imaging; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging / Q000379:methods*