title: Pharmacogenomics and patient care: one size does not fit all.
abstract: The time is ripe to assess whether pharmacogenomics research--the study of the genetic basis for variation in drug response--has provided important insights into a personalized approach to prescribing and dosing medications. Here, we describe the status of the field and approaches for addressing some of the open questions in pharmacogenomics research and use of genetic testing in guiding drug therapy.
authors.affiliation: Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 94143, USA. kathy.giacomini@ucsf.edu
authors.forename: Kathleen M
authors.initials: KM
authors.lastname: Giacomini
authors.forename: Sook Wah
authors.initials: SW
authors.lastname: Yee
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Ratain
authors.forename: Richard M
authors.initials: RM
authors.lastname: Weinshilboum
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Kamatani
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Nakamura
mesh_terms: D011307:Drug Prescriptions; D014644:Genetic Variation; D006801:Humans; D005791:Patient Care; D010597:Pharmacogenetics; D057285:Precision Medicine; D057170:Translational Research, Biomedical