title: Metabolic syndrome and population attributable risk among HIV/AIDS patients: comparison between NCEP-ATPIII, IDF and AHA/NHLBI definitions.
abstract: BACKGROUND
  Metabolic Syndrome (MetS) is based on the same individual components, but has received several amendments to the original definition. In this study, we verified the prevalence of metabolic syndrome according to different criteria, and the impact of each component on the diagnostic.
  
  
  METHODS
  This cross-sectional study enrolled HIV infected patients from a HIV/AIDS reference Center in southern Brazil. Metabolic syndrome was identified according to the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (NCEP-ATPIII), the International Diabetes Federation (IDF) and the American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI) criteria, and using a standardized questionnaire and blood testing.
  
  
  RESULTS
  A sample of 1240, out of 1295, HIV-infected patients was enrolled. Males were on average older, more educated, and had shorter time since the HIV diagnosis. The population attributable risk (PAR) for waist circumference explained 80% of the prevalence among men and women (AHA/NHLBI criteria). Triglycerides had the highest impact on prevalence of metabolic syndrome according to all criteria, independently of age, skin color and HAART use, among men.
  
  
  CONCLUSIONS
  In this large sample of HIV infected patients, the overall prevalence of metabolic syndrome, under either classification, was noticeable and the AHA/NHLBI definition accounted for the highest prevalence.
authors.affiliation: Postgraduate Studies Program in Epidemiology, School of Medicine, Universidade Federal do Rio Grande do Sul, R, Ramiro Barcelos 2600, Porto Alegre, RS, CEP 90035-003, Brazil. scfuchs@terra.com.br.
authors.forename: Paulo R
authors.initials: PR
authors.lastname: Alencastro
authors.forename: Fernando H
authors.initials: FH
authors.lastname: Wolff
authors.forename: Renato R
authors.initials: RR
authors.lastname: Oliveira
authors.forename: Maria Letícia R
authors.initials: ML
authors.lastname: Ikeda
authors.forename: Nêmora T
authors.initials: NT
authors.lastname: Barcellos
authors.forename: Ajácio B M
authors.initials: AB
authors.lastname: Brandão
authors.forename: Sandra C
authors.initials: SC
authors.lastname: Fuchs