title: Myocardial viability assessment in 18FDG PET/CT study (18FDG PET myocardial viability assessment).
abstract: Accurate identification of viable myocardium is crucial in patient qualification for medical or surgical treatment. Only persons with confirmed cardiac viability will benefit from revascularization procedures. It is also well known, that the amount of viable myocardium assessed preoperatively is the best indicator of long term cardiac event free survival after cardiac intervention.There are several diagnostic approaches used in current clinical practice for assessment of myocardial viability. Analysis of wall thickness or myocardial contraction, evaluation of cardiac perfusion or metabolism can be assessed using following modalities: Echocardiography, Cardiac Molecular Imaging techniques (PET, SPECT), Cardiovascular MR or Cardiovascular CT. The article describes the methods and problems of viability assessment in 18FDG PET study. PET imaging has proved its accuracy and reproducibility for myocardial ischemia and viability assessment. However this unique in its ability for showing the particular substrate metabolism technique has unfortunately some disadvantages: currently achieved PET resolution is 0.4 cm. However the combined devices multislice computed tomography scanners with PET (PET/CT) are now widely used in clinical practice. This combination allows for wider morphologic assessments: coronary calcium scoring and non-invasive coronary angiography may be added to myocardial perfusion/metabolic imaging if necessary.
authors.affiliation: Nuclear Medicine Department Warsaw Medical University, Warsaw, Poland. makob@amwaw.edu.pl
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Kobylecka
authors.forename: Joanna
authors.initials: J
authors.lastname: Mączewska
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Fronczewska-Wieniawska
authors.forename: Tomasz
authors.initials: T
authors.lastname: Mazurek
authors.forename: Maria Teresa
authors.initials: MT
authors.lastname: Płazińska
authors.forename: Leszek
authors.initials: L
authors.lastname: Królicki
mesh_terms: D004194:Disease; D019788:Fluorodeoxyglucose F18; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D064847:Multimodal Imaging / Q000379:methods*; D009206:Myocardium / Q000166:cytology* / Q000378:metabolism / Q000473:pathology; D049268:Positron-Emission Tomography; D014022:Tissue Survival; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18