title: Comment on "The geometric structure of the brain fiber pathways".
abstract: Wedeen et al. (Reports, 30 March 2012, p. 1628) proposed a geometrical grid pattern in the brain that could help the understanding of the brain's organization and connectivity. We show that whole-brain fiber crossing quantification does not support their theory. Our results suggest that the grid pattern is most likely an artifact attributable to the limitations of their method.
authors.affiliation: NATBRAINLAB, Department of Neuroimaging, Institute of Psychiatry, King's College London, London, UK. m.catani@iop.kcl.ac.uk
authors.forename: Marco
authors.initials: M
authors.lastname: Catani
authors.forename: Istvan
authors.initials: I
authors.lastname: Bodi
authors.forename: Flavio
authors.initials: F
authors.lastname: Dell'Acqua
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D006801:Humans; D009412:Nerve Fibers; D009434:Neural Pathways / Q000033:anatomy & histology*