title: Ultralow voltage, OTFT-based sensor for label-free DNA detection.
abstract: An organic ultralow voltage field effect transistor for DNA hybridization detection is presented. The transduction mechanism is based on a field-effect modulation due to the electrical charge of the oligonucleotides, so label-free detection can be performed. The device shows a sub-nanometer detection limit and unprecedented selectivity with respect to single nucleotide polymorphism.
authors.affiliation: Dipartimento di Ingegneria Elettrica ed Elettronica, Università di Cagliari, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Lai
authors.forename: M
authors.initials: M
authors.lastname: Demelas
authors.forename: G
authors.initials: G
authors.lastname: Casula
authors.forename: P
authors.initials: P
authors.lastname: Cosseddu
authors.forename: M
authors.initials: M
authors.lastname: Barbaro
authors.forename: A
authors.initials: A
authors.lastname: Bonfiglio
mesh_terms: D004247:DNA / Q000032:analysis* / Q000737:chemistry; D004553:Electric Conductivity; D004560:Electricity; D009693:Nucleic Acid Hybridization; D009930:Organic Chemicals / Q000737:chemistry*; D014173:Transistors, Electronic
chemical_list: D009930:Organic Chemicals; D004247:DNA