title: Complete genome sequence of a J subgroup avian leukosis virus isolated from local commercial broilers.
abstract: Subgroup J avian leukosis virus (ALV-J) isolate GDKP1202 was isolated from a 50-day-old local yellow commercial broiler in the Guangdong province of China in 2012. Here we report the complete genomic sequence of the GDKP1202 isolate, which caused high mortality, serious growth suppression, thymic atrophy, and liver enlargement in commercial broilers. A novel potential binding site (5'-GGCACCTCC-3') for c-myb was identified in the GDKP1202 genome. These findings will provide additional insights into the molecular characteristics in the genomes and pathogenicity of ALV-J.
authors.affiliation: College of Animal Science, South China Agricultural University, Guangzhou, China.
authors.forename: Hongxin
authors.initials: H
authors.lastname: Li
authors.forename: Chunyi
authors.initials: C
authors.lastname: Xue
authors.forename: Jun
authors.initials: J
authors.lastname: Ji
authors.forename: Shuang
authors.initials: S
authors.lastname: Chang
authors.forename: Huiqin
authors.initials: H
authors.lastname: Shang
authors.forename: Lingjun
authors.initials: L
authors.lastname: Zhang
authors.forename: Jingyun
authors.initials: J
authors.lastname: Ma
authors.forename: Yingzuo
authors.initials: Y
authors.lastname: Bi
authors.forename: Qingmei
authors.initials: Q
authors.lastname: Xie
mesh_terms: D000818:Animals; D001353:Avian Leukosis / Q000401:mortality / Q000473:pathology / Q000821:virology; D001354:Avian Leukosis Virus / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D001665:Binding Sites; D002645:Chickens; D002681:China; D016679:Genome, Viral; D008969:Molecular Sequence Data; D011485:Protein Binding; D020598:Proto-Oncogene Proteins c-myb / Q000378:metabolism; D012367:RNA, Viral / Q000235:genetics*; D017422:Sequence Analysis, DNA
chemical_list: D020598:Proto-Oncogene Proteins c-myb; D012367:RNA, Viral