title: Synthesis and photobiocidal properties of cationic porphyrin-grafted paper.
abstract: We report on the synthesis of cellulose paper bearing a cationic porphyrin, designed for antimicrobial applications. Tricationic porphyrin has been covalently grafted on paper, without previous chemical modification of the cellulosic support, using 1,3,5-triazine derivative as linker. The obtained porphyrin-grafted paper was characterized by infrared (ATR-FTIR), UV-visible and diffuse reflectance UV-vis (DRUV) spectroscopies to confirm the triazine linkage. Thermogravimetric analysis (TGA) was used to investigate thermal properties of grafted paper. Antimicrobial activity of porphyrin-cellulose material was tested under visible light irradiation against Staphylococcus aureus and Escherichia coli. The two bacterial strains deposited on the resulting photosensitizing filter paper are efficiently killed after illumination.
authors.affiliation: Université de Limoges, Laboratoire de Chimie des Substances Naturelles, EA 1069, 123 avenue Albert Thomas, 87060 Limoges, France.
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Mbakidi
authors.forename: Klara
authors.initials: K
authors.lastname: Herke
authors.forename: Sandra
authors.initials: S
authors.lastname: Alvès
authors.forename: Vincent
authors.initials: V
authors.lastname: Chaleix
authors.forename: Robert
authors.initials: R
authors.lastname: Granet
authors.forename: Pierre
authors.initials: P
authors.lastname: Krausz
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Leroy-Lhez
authors.forename: Tan-Sothea
authors.initials: TS
authors.lastname: Ouk
authors.forename: Vincent
authors.initials: V
authors.lastname: Sol
mesh_terms: D058491:Bacterial Load / Q000187:drug effects / Q000528:radiation effects; D002482:Cellulose / Q000737:chemistry; D060326:Chemistry Techniques, Synthetic; D004926:Escherichia coli / Q000187:drug effects / Q000502:physiology / Q000528:radiation effects; D008027:Light; D010209:Paper; D017319:Photosensitizing Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D011166:Porphyrins / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000502:physiology / Q000528:radiation effects
chemical_list: D017319:Photosensitizing Agents; D011166:Porphyrins; D002482:Cellulose