title: Ureteric stricture: an unusual presentation of metastatic prostate adenocarcinoma.
abstract: We describe an unusual case of a prostatic adenocarcinoma presenting with a ureteric stricture secondary to a discrete metastatic lesion. A 76-year-old man presented with a short history of right loin pain. Initial examination was unremarkable, digital rectal examination was normal  and prostate specific antigen was within normal range. Computed tomography showed right hydronephrosis and a distal ureteric stricture. A distal ureteric transitional cell carcinoma was thought to be most likely. A nephroureterectomy was carried out and histology revealed a skipped lesion  of a metastatic prostate adenocarcinoma. Metastatic lesions to the ureters due to prostate cancer are rare. It was believed to be secondary to a transitional cell carcinoma as there was no evidence initially to suggest prostatic disease as the cause. A prostatic adenocarcinoma should be considered  in the differential diagnosis of any lesions in the ureter believed to have a malignant origin.
authors.affiliation: Leeds Teaching Hospitals NHS Trust, UK.
authors.forename: S
authors.initials: S
authors.lastname: Jallad
authors.forename: R
authors.initials: R
authors.lastname: Turo
authors.forename: M
authors.initials: M
authors.lastname: Kimuli
authors.forename: J
authors.initials: J
authors.lastname: Smith
authors.forename: S
authors.initials: S
authors.lastname: Jain
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology*; D000368:Aged; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000150:complications / Q000473:pathology*; D014516:Ureteral Neoplasms / Q000556:secondary*; D014517:Ureteral Obstruction / Q000209:etiology*