title: A new strategy for imaging biomolecular events through interactions between liquid crystals and oil-in-water emulsions.
abstract: In this study, we demonstrate a new strategy to image biomolecular events through interactions between liquid crystals (LCs) and oil-in-water emulsions. The optical response had a dark appearance when a nematic LC, 4-cyano-4'-pentylbiphenyl (5CB), is in contact with emulsion droplets of glyceryl trioleate (GT). In contrast, the optical response had a bright appearance when 5CB is in contact with GT emulsions decorated with surfactants such as sodium oleate. Since lipase can hydrolyze GT and produce oleic acid, the optical response also displays a bright appearance after 5CB has been in contact with a mixture of lipase and GT emulsions. These results indicate the feasibility of monitoring biomolecular events through interactions between LCs and oil-in-water emulsions.
authors.affiliation: Department of Chemistry, Gachon University, Bokjeong-Dong, Seongnam-City, Gyeonggi-Do 461-701, Korea.
authors.forename: Qiong-Zheng
authors.initials: QZ
authors.lastname: Hu
authors.forename: Chang-Hyun
authors.initials: CH
authors.lastname: Jang
mesh_terms: D001713:Biphenyl Compounds / Q000737:chemistry; D004655:Emulsions / Q000737:chemistry*; D008049:Lipase / Q000378:metabolism; D050866:Liquid Crystals / Q000737:chemistry*; D008853:Microscopy; D009570:Nitriles / Q000737:chemistry; D009821:Oils / Q000737:chemistry*; D019301:Oleic Acid / Q000737:chemistry / Q000378:metabolism; D014867:Water / Q000737:chemistry*
chemical_list: D001713:Biphenyl Compounds; D004655:Emulsions; D009570:Nitriles; D009821:Oils; D014867:Water; D019301:Oleic Acid; C433919:4-cyano-4'-pentylbiphenyl; D008049:Lipase