title: Adenosine deaminase--the non-invasive marker of tuberculosis.
abstract: Pulmonary tuberculosis is the India's biggest health problem especially in rural areas. A quick and dependable investigation is absolutely essential. Adenosine deaminase was estimated from the biological fluids (ascitic/pleural/CSF) with the help of the kit obtained from Tulip India Pvt Ltd. The method is based on the principle of Galati & Giusti colorimetric method. The method is simple, inexpensive and results are also reproducible. Elevation of adenosine deaminase has shown high specificity in all biological fluids. As the estimation principle is based on synthesis of ammonia so there is limitation of the procedure when the site is kidney. Similarly if the site is skin, as fluid cannot be collected from the site, adenosine deaminase estimation is also not possible.
authors.affiliation: Peerless Hospital & BK Roy Research Centre, Kolkata 700094.
authors.forename: Shyamali
authors.initials: S
authors.lastname: Pal
authors.forename: Sanjoy
authors.initials: S
authors.lastname: Gupta
mesh_terms: D000243:Adenosine Deaminase / Q000032:analysis*; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000032:analysis; D003124:Colorimetry; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010996:Pleural Effusion / Q000201:enzymology*; D016133:Polymerase Chain Reaction / Q000379:methods*; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000175:diagnosis*; D055815:Young Adult
chemical_list: D015415:Biomarkers; D000243:Adenosine Deaminase