title: Infant behaviors are predictive of functional somatic symptoms at ages 5-7 years: results from the Copenhagen Child Cohort CCC2000.
abstract: OBJECTIVE
  To investigate infancy predictors of impairing functional somatic symptoms (FSS) at child ages 5-7 years with a focus on problems with feeding, sleep, and tactile reactivity.
  
  
  METHODS
  This study is part of a longitudinal birth cohort study, Copenhagen Child Cohort CCC2000. Child health, development, and functioning were assessed by community health nurses at 4 home visits from birth to age 10 months. FSS at ages 5-7 years were measured by the Soma Assessment Interview in 1327 children. Sociodemographic data and information on maternal psychiatric illness were obtained from the Danish National Registers.
  
  
  RESULTS
  Multiple logistic regression analysis controlled for maternal psychiatric illness and annual household income revealed that combined infancy regulatory problems (ie, at least 2 of 3 problems of feeding, sleeping, or tactile reactivity during the first 10 months of living) predicted impairing FSS at 5-7 years (aOR = 2.9, 95% CI: 1.3-6.6). Maternal psychiatric illness during the child's first year of living was also associated with later child FSS (aOR = 7.1, 95% CI: 1.8-27.8).
  
  
  CONCLUSIONS
  Regulatory problems may be an early marker of disturbed sensory reactivity in young children, which together with maternal psychiatric problems, point to possible early risk mechanisms of impairing FSS in childhood.
authors.affiliation: Regional Center for Child and Adolescent Psychiatry, Aarhus University Hospital, Aarhus, Denmark.
authors.forename: Charlotte Ulrikka
authors.initials: CU
authors.lastname: Rask
authors.forename: Eva
authors.initials: E
authors.lastname: Ørnbøl
authors.forename: Else Marie
authors.initials: EM
authors.lastname: Olsen
authors.forename: Per
authors.initials: P
authors.lastname: Fink
authors.forename: Anne Mette
authors.initials: AM
authors.lastname: Skovgaard
mesh_terms: D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007223:Infant; D018730:Infant Behavior; D008137:Longitudinal Studies; D008297:Male; D015999:Multivariate Analysis; D011379:Prognosis; D011446:Prospective Studies; D011602:Psychophysiologic Disorders / Q000175:diagnosis / Q000209:etiology*