title: The effect of different strengths of extremely low-frequency electric fields on antioxidant status, lipid peroxidation, and visual evoked potentials.
abstract: The aim of the study was to investigate the effects of extremely low-frequency electric field (ELF EF) on visual evoked potential (VEP), thiobarbituric acid reactive substances (TBARS), total antioxidant status (TAS), total oxidant status (TOS), and oxidant stress index (OSI). Thirty female Wistar rats, aged 3 months, were divided into three equal groups: Control (C), the group exposed to EF at 12 kV/m strength (E12), and the group exposed to EF at 18 kV/m strength (E18). Electric field was applied to the E12 and E18 groups for 14 days (1 h/day). Brain and retina TBARS, TOS, and OSI were significantly increased in the E12 and E18 groups with respect to the control group. Also, TBARS levels were significantly increased in the E18 group compared with the E12 group. Electric fields significantly decreased TAS levels in both brain and retina in E12 and E18 groups with respect to the control group. All VEP components were significantly prolonged in rats exposed to electric fields compared to control group. In addition, all latencies of VEP components were increased in the E18 group with respect to the E12 group. It is conceivable to suggest that EF-induced lipid peroxidation may play an important role in changes of VEP parameters.
authors.affiliation: Department of Biophysics, Akdeniz University, Antalya, Turkey. pakkiraz@akdeniz.edu.tr
authors.forename: Deniz
authors.initials: D
authors.lastname: Akpinar
authors.forename: Nihal
authors.initials: N
authors.lastname: Ozturk
authors.forename: Sukru
authors.initials: S
authors.lastname: Ozen
authors.forename: Aysel
authors.initials: A
authors.lastname: Agar
authors.forename: Piraye
authors.initials: P
authors.lastname: Yargicoglu
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D001921:Brain / Q000378:metabolism / Q000502:physiology / Q000528:radiation effects; D004574:Electromagnetic Fields; D005074:Evoked Potentials, Visual / Q000528:radiation effects*; D005260:Female; D015227:Lipid Peroxidation / Q000528:radiation effects*; D018384:Oxidative Stress / Q000528:radiation effects; D051381:Rats; D017208:Rats, Wistar; D012160:Retina / Q000378:metabolism / Q000528:radiation effects; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
chemical_list: D000975:Antioxidants; D017392:Thiobarbituric Acid Reactive Substances