title: Pantothenate - kinase associated neurodegeneration.
abstract: Neurodegeneration with brain iron accumulation is a group of disorders, the commonest of which is PKAN (Pantothenate kinase associated neurodegeneration). We present here, a case of 18 year old boy with progressive dementia, pyramidal and extrapyramidal involvement, dysarthria, seizures and myoclonus. The patient was diagnosed as PKAN (formerly Hallervorden Spatz disease) after "eye of tiger" appearance on neuro-imaging.
authors.affiliation: Medicine Dept., Surat Medical Institute of Medical Education and Research (SMIMER), Surat.
authors.forename: Alpana
authors.initials: A
authors.lastname: Parmar
authors.forename: Shruti
authors.initials: S
authors.lastname: Khare
authors.forename: Vipul
authors.initials: V
authors.lastname: Srivastav
mesh_terms: D000293:Adolescent; D018680:Cholinergic Antagonists / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D006211:Pantothenate Kinase-Associated Neurodegeneration / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D018680:Cholinergic Antagonists; D009125:Muscle Relaxants, Central