title: [Advance in biomechanical study of embryonic vascular system development].
abstract: Embryonic vascular system development is a complex process, whose progress is regulated by a variety of the stimulation and inhibition signals, and these signals must play synergistic effect so as to ensure that each stage of vascular development can proceed normally. The vascular development is controlled by the gene to a certain extent, and has received extensive attention.  Recent studies have revealed the biomechanical role is necessary to embryonic vascular development, in which different mechanism of cell biomechanics is involved. In this review, we summarize the latest research progress on the role of biomechanical factors during embryonic vascular system development.
authors.affiliation: Key Laboratory of Biorheology and Technology (Chongqing University), Ministry of Education, Chongqing Engineering Laboratory in Vascular Implants, Laboratory of Mechano-developmental Biology, Bioengineering College of Chongqing University, Chongqing 400044, China. linfq007@163.com
authors.forename: Xiang
authors.initials: X
authors.lastname: Xie
authors.forename: Jian-Jun
authors.initials: JJ
authors.lastname: Hu
authors.forename: Gui-Xue
authors.initials: GX
authors.lastname: Wang
mesh_terms: D000818:Animals; D001158:Arteries / Q000196:embryology; D001696:Biomechanical Phenomena; D001808:Blood Vessels / Q000196:embryology* / Q000502:physiology*; D002448:Cell Adhesion; D002454:Cell Differentiation; D002465:Cell Movement; D042783:Endothelial Cells / Q000166:cytology / Q000378:metabolism; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000378:metabolism; D006801:Humans; D032389:Myocytes, Smooth Muscle / Q000166:cytology / Q000378:metabolism; D014680:Veins / Q000196:embryology