title: Expanding the chemical diversity of spirooxindoles via alkylative pyridine dearomatization.
abstract: A mild and practical synthesis of spirooxindole [1,3]oxazino derivatives from N-substituted isatins and 1,3-dicarbonyl compounds with pyridine derivatives is reported. The reactions provided good to excellent yields. Further exploration of the molecular diversity of these compounds is demonstrated through Diels-Alder reactions.
authors.affiliation: Department of Chemistry and Center for Chemical Methodology and Library Development (CMLD-BU), Boston University, 590 Commonwealth Avenue, Boston, Massachusetts 02215, USA.
authors.forename: Chunhui
authors.initials: C
authors.lastname: Dai
authors.forename: Bo
authors.initials: B
authors.lastname: Liang
authors.forename: Corey R J
authors.initials: CR
authors.lastname: Stephenson