title: [Liquid nitrogen biobank: a resource for biomedical research].
abstract: Biobanks are a critical resource for "omics" technologies in order to dissect molecular mechanism and gene-environmental interactions of common diseases, such as cancer, cardiovascular diseases, diabetes, and neurodegenerative diseases. Progress in basic biomedicine may contribute to advance personalised medicine in which treatments will no longer be "one size fits all", but instead "tailored" to the molecular and genetic profile of each patient. Currently, there are major efforts worldwide to professionalize biobanks in order to move ahead from a "do-it-yourself" tissue collection - as is most frequent at present - for providing high quality preservation and storage of biological samples with potentially greater scientific impact. In this paper, we describe our recent experience in the design and development of a high-security liquid nitrogen storage system (-196°C) as a key resource for biomedical research.
authors.affiliation: Unità Banca Biologica, Istituto di Fisiologia Clinica, Consiglio Naionale delle Richerche, Pisa.
authors.forename: Stefano
authors.initials: S
authors.lastname: Turchi
authors.forename: Antonella
authors.initials: A
authors.lastname: Mercuri
authors.forename: Guido
authors.initials: G
authors.lastname: Lazzerini
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: Chiesa
authors.forename: Laura
authors.initials: L
authors.lastname: Musacchio
authors.forename: Sabrina
authors.initials: S
authors.lastname: Tozzi
authors.forename: Mauro
authors.initials: M
authors.lastname: Boni
authors.forename: Ottavio
authors.initials: O
authors.lastname: Zirilli
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Andreassi
mesh_terms: D018070:Biological Specimen Banks / Q000941:ethics / Q000458:organization & administration*; D035843:Biomedical Research / Q000941:ethics / Q000458:organization & administration*; D001769:Blood; D006801:Humans; D007558:Italy; D055432:Metabolomics; D009584:Nitrogen; D010949:Plasma; D040901:Proteomics; D044967:Serum; D013048:Specimen Handling / Q000592:standards; D059467:Transcriptome
chemical_list: D009584:Nitrogen