title: Electrophysiological subtypes and prognosis of Guillain-Barré syndrome in northeastern China.
abstract: BACKGROUND
  The purpose of this study was to assess the electrophysiological subtypes and prognosis of Guillain-Barré syndrome (GBS) in northeastern China.
  
  
  METHODS
  Ninety-nine patients with GBS were recruited between 2006 and 2010 and retrospectively reviewed.
  
  
  RESULTS
  Sixty-seven percent of patients had acute inflammatory demyelinating polyneuropathy (AIDP). Patients with acute motor axonal neuropathy (AMAN) had more severe symptoms at onset of GBS, and intravenous immunoglobulin (IVIg) was less effective in these patients. The prognosis may have been associated with the severity of the illness and did not differ between AMAN and AIDP patients. Abnormal motor nerve conduction studies (NCS) of the lower limbs and sensory NCS of the upper limbs with normal sural sensory nerve studies were the main electrophysiological features of AIDP.
  
  
  CONCLUSIONS
  AIDP is the main subtype of GBS, and it has specific electrophysiological characteristics in northeastern China. The prognosis of patients with AMAN was similar to that of patients with AIDP. Moreover, IVIg was more effective in patients with AIDP.
authors.affiliation: Department of Neurology, First Hospital, Jilin University, No. 71 Xinmin Street, Changchun, PR China. dearlea@live.cn
authors.forename: Yuqin
authors.initials: Y
authors.lastname: Ye
authors.forename: Keren
authors.initials: K
authors.lastname: Wang
authors.forename: Fang
authors.initials: F
authors.lastname: Deng
authors.forename: Yingqi
authors.initials: Y
authors.lastname: Xing
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001369:Axons / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D002681:China; D004568:Electrodiagnosis; D005260:Female; D005500:Follow-Up Studies; D020275:Guillain-Barre Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology*; D009431:Neural Conduction / Q000502:physiology*; D011379:Prognosis; D012189:Retrospective Studies