title: From small nodule to overt HCC: a multistep process of carcinogenesis as seen during surveillance.
abstract: Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death in the world. Despite many diagnostic and therapeutic tools are now available to improve survival and reduce its recurrence, prognosis is closely conditioned by the time of diagnosis. Surveillance and early diagnosis are crucial for a successful therapy. We report a clinical case from the HCC archive of the Hepatocatt meetings held in Ge-melli Hospital (Catholic University of Rome). The case describes a tumor progression in a multistep process from a small liver nodule to overt HCC and its management by a multidisciplinary team.
authors.affiliation: Department of Internal Medicine and Gastroenterology, Catholic University of the Sacred Heart, Rome, Italy. emanurinni@yahoo.it
authors.forename: E
authors.initials: E
authors.lastname: Rinninella
authors.forename: M A
authors.initials: MA
authors.lastname: Zocco
authors.forename: A
authors.initials: A
authors.lastname: De Gaetano
authors.forename: R
authors.initials: R
authors.lastname: Iezzi
authors.forename: M
authors.initials: M
authors.lastname: Campanale
authors.forename: V
authors.initials: V
authors.lastname: Cesario
authors.forename: F
authors.initials: F
authors.lastname: Barbaro
authors.forename: F R
authors.initials: FR
authors.lastname: Ponziani
authors.forename: G
authors.initials: G
authors.lastname: Caracciolo
authors.forename: S
authors.initials: S
authors.lastname: Triarico
authors.forename: A
authors.initials: A
authors.lastname: Tortora
authors.forename: G
authors.initials: G
authors.lastname: Ianiro
authors.forename: A
authors.initials: A
authors.lastname: Gasbarrini
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D002471:Cell Transformation, Neoplastic; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed