title: Cervical cancer in Brunei Darussalam.
abstract: BACKGROUND
  Cervical cancer caused by the human papilloma virus (HPV) is a common cancer in women. There is no published data on the recent incidence of cervical dysplasia, cervical cancer and genital warts caused by the different types of HPVs in Brunei Darussalam.
  
  
  METHODS
  A cross-sectional, retrospective study was conducted utilising data from patients diagnosed with cervical cancer during the period 2005-2009 in Brunei Darussalam. The varying incidences of different types of cervical lesions among various ethnic and age groups, and in the overall population, were determined.
  
  
  RESULTS
  The mean age-standardised incidence of invasive cervical cancer during the five-year period was 24.9 per 100,000 women per year (95% confidence interval [CI] 21.7, 28.1). Age-specific invasive cervical cancer incidence peaked in the age group 45-59 years. Chinese females tended to have a higher incidence of invasive cervical cancer (28.2 per 100,000 women per year; 95% CI 17.8, 38.7) than Malay females (20.6 per 100,000 women per year; 95% CI 17.1, 24.2), while other ethnic groups in Brunei Darussalam had a significantly lower incidence (6.5 per 100,000 women per year; 95% CI 3.0, 10.0).
  
  
  CONCLUSIONS
  The results suggest that Brunei Darussalam has a relatively higher incidence of cervical cancer compared to its neighbouring countries. The findings support the need for more comprehensive screening, public education programmes and vaccination against HPV in the country.
authors.affiliation: 1Institute of Health Sciences, Universiti Brunei Darussalam, Gadong, Brunei Darussalam.
authors.forename: Melissa Ying Ngo
authors.initials: MY
authors.lastname: Lee
authors.forename: Premasiri Upali
authors.initials: PU
authors.lastname: Telisinghe
authors.forename: Ranjan
authors.initials: R
authors.lastname: Ramasamy
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002010:Brunei / Q000453:epidemiology; D002648:Child; D002681:China / Q000208:ethnology; D003218:Condylomata Acuminata / Q000517:prevention & control; D003430:Cross-Sectional Studies; D005260:Female; D006291:Health Policy; D006801:Humans; D007114:Immunization; D015994:Incidence; D008296:Malaysia / Q000208:ethnology; D008875:Middle Aged; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000208:ethnology* / Q000473:pathology / Q000517:prevention & control