title: [Use of botulinum toxin in a patient with pendular congenital nystagmus].
abstract: METHODS
  We report the case of a 5 month-old male diagnosed with congenital nystagmus and oculocutaneous albinism. The initial examination showed pendular horizontal nystagmus with high amplitude and without blocking position or foveal fixation periods. A 2.5 IU injection of botulinum toxin was administered in the horizontal rectus muscles of both eyes in two sessions separated by 6 weeks. This led to a decrease in amplitude of nystagmus and early development of binocular visual acuity of 4.8cycles/cm.
  
  
  CONCLUSIONS
  Faced with diagnosis of horizontal nystagmus in the early stages of development, and in order to avoid periods of foveal fixation, the use of botulinum toxin leads to a temporary reduction in its amplitude and an improvement in visual acuity with low complication rates. Given the possibility of spontaneous improvement described in these patients, studies are needed with longer follow-up to establish the advantage of long term treatment.
authors.affiliation: Universidad Complutense de Madrid, Hospital Clínico San Carlos, Madrid, España.
authors.forename: E
authors.initials: E
authors.lastname: Hernández-García
authors.forename: R
authors.initials: R
authors.lastname: Gómez-De-Liaño-Sánchez
mesh_terms: D016115:Albinism, Oculocutaneous / Q000150:complications; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D008297:Male; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D020417:Nystagmus, Congenital / Q000188:drug therapy*; D009759:Nystagmus, Pathologic / Q000188:drug therapy*; D016896:Treatment Outcome; D015348:Vision, Binocular; D014792:Visual Acuity
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A