title: Organocatalytic asymmetric addition of malonates to unsaturated 1,4-diketones.
abstract: The organocatalytic Michael addition of malonates to symmetric unsaturated 1,4-diketones catalyzed by thiourea and squaramide derivatives with Cinchona alkaloids afforded the formation of a new C-C bond in high yields (up to 98%) and enantiomeric purities (up to 93%). The absolute configuration of the product was suggested from comparison of the experimental and calculated VCD spectra of the reaction product 3a.
authors.affiliation: Department of Chemistry, Tallinn University of Technology, Akadeemia tee 15, 12618 Tallinn, Estonia.
authors.forename: Sergei
authors.initials: S
authors.lastname: Zari
authors.forename: Tiiu
authors.initials: T
authors.lastname: Kailas
authors.forename: Marina
authors.initials: M
authors.lastname: Kudrjashova
authors.forename: Mario
authors.initials: M
authors.lastname: Oeren
authors.forename: Ivar
authors.initials: I
authors.lastname: Järving
authors.forename: Toomas
authors.initials: T
authors.lastname: Tamm
authors.forename: Margus
authors.initials: M
authors.lastname: Lopp
authors.forename: Tõnis
authors.initials: T
authors.lastname: Kanger