title: RNAi screening of the human colorectal cancer genome identifies multifunctional tumor suppressors regulating epithelial cell invasion.
authors.forename: Peter
authors.initials: P
authors.lastname: Ly
authors.forename: Ugur
authors.initials: U
authors.lastname: Eskiocak
authors.forename: Chelsea R
authors.initials: CR
authors.lastname: Parker
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Harris
authors.forename: Woodring E
authors.initials: WE
authors.lastname: Wright
authors.forename: Jerry W
authors.initials: JW
authors.lastname: Shay
mesh_terms: D025601:Adenomatous Polyposis Coli Protein / Q000235:genetics; D058534:Class I Phosphatidylinositol 3-Kinases; D015179:Colorectal Neoplasms / Q000235:genetics* / Q000473:pathology; D004847:Epithelial Cells / Q000473:pathology*; D016147:Genes, Tumor Suppressor; D016158:Genes, p53; D006801:Humans; D009154:Mutation; D009361:Neoplasm Invasiveness / Q000235:genetics; D019869:Phosphatidylinositol 3-Kinases / Q000235:genetics; D011518:Proto-Oncogene Proteins / Q000235:genetics; D016283:Proto-Oncogene Proteins p21(ras); D034622:RNA Interference; D034741:RNA, Small Interfering; D017422:Sequence Analysis, DNA; D018631:ras Proteins / Q000235:genetics
chemical_list: C555337:APC protein, human; D025601:Adenomatous Polyposis Coli Protein; C117307:KRAS protein, human; D011518:Proto-Oncogene Proteins; D034741:RNA, Small Interfering; D019869:Phosphatidylinositol 3-Kinases; D058534:Class I Phosphatidylinositol 3-Kinases; C484760:PIK3CA protein, human; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins