title: A new cyclic tetrapeptide from the jellyfish-derived fungus Phoma sp.
abstract: A new cyclic tetrapeptide (1), along with known congeners (2, 3), was isolated from the fungus Phoma sp. derived from the giant jellyfish Nemopilema nomurai. The absolute configuration of 1 was determined using the modified Mosher's method and Marfey's method. Compound 1 displayed a weak suppressive effect on the production of nitric oxide (NO) in murine macrophage cells (RAW264.7) without notable cytotoxicity.
authors.affiliation: College of Pharmacy, Pusan National University, Busan 609–735, Republic of Korea.
authors.forename: Eun La
authors.initials: EL
authors.lastname: Kim
authors.forename: Jian Lin
authors.initials: JL
authors.lastname: Li
authors.forename: Bin
authors.initials: B
authors.lastname: Xiao
authors.forename: Jongki
authors.initials: J
authors.lastname: Hong
authors.forename: Eun Sook
authors.initials: ES
authors.lastname: Yoo
authors.forename: Won Duk
authors.initials: WD
authors.lastname: Yoon
authors.forename: Jee H
authors.initials: JH
authors.lastname: Jung
mesh_terms: D000818:Animals; D001203:Ascomycota / Q000737:chemistry*; D002460:Cell Line; D051379:Mice; D008958:Models, Molecular; D008968:Molecular Conformation; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification*; D037401:Scyphozoa / Q000382:microbiology*
chemical_list: D010456:Peptides, Cyclic