title: Isolated primary testicular B lymphoblastic lymphoma:  an unusual presentation.
abstract: Acute lymphoblastic leukemia (ALL) is the most common cancer in children and adolescents. Clinical presentation often reflects bone marrow involvement and consequences of bone marrow failure. Microscopic involvement of the testis is rare, occurring in about 2% of cases. We present a case of a 3-year-old child who displayed unilateral macroorchidism as the only clinical symptom of ALL. Although the patient presented with localized disease, he was treated with systemic chemotherapy without recurrence. In this report, we review the current literature on ALL testicular involvement, diagnosis, and treatment.
authors.affiliation: Department of Surgery, Columbia University College of Physicians and Surgeons, New York, NY, USA. alg2025@columbia.edu
authors.forename: Alejandro V
authors.initials: AV
authors.lastname: Garcia
authors.forename: Bachir
authors.initials: B
authors.lastname: Alobeid
authors.forename: Jocelyn M
authors.initials: JM
authors.lastname: Traina
authors.forename: Susie S
authors.initials: SS
authors.lastname: Chen
authors.forename: Michael A
authors.initials: MA
authors.lastname: Weiner
authors.forename: William
authors.initials: W
authors.lastname: Middlesworth
mesh_terms: D002675:Child, Preschool; D006801:Humans; D008297:Male; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology