title: Cobalt-mediated synthesis of the tricyclo[5.2.1.0(1,6)]decene framework in solanoeclepin A.
abstract: The stereocontrolled synthesis of the highly strained, tricyclo[5.2.1.0(1,6)]decene skeleton (C) of solanoeclepin A has been achieved through two key transformations: a [2,3]-Wittig rearrangement of allylpropargyl ether (A) to propargyl alcohol (B) having a trans-fused perhydroindane framework and the formation of the cyclobutane via a cobalt-mediated Hosomi-Sakurai type cyclization of an acetylene dicobalthexacarbonyl complex.
authors.affiliation: Department of Chemistry, National Tsing Hua University, 101, Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan.
authors.forename: Kuo-Wei
authors.initials: KW
authors.lastname: Tsao
authors.forename: Chia-Yi
authors.initials: CY
authors.lastname: Cheng
authors.forename: Minoru
authors.initials: M
authors.lastname: Isobe
mesh_terms: D001952:Bridged-Ring Compounds / Q000737:chemistry*; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D006586:Hexanes / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000138:chemical synthesis*; D008958:Models, Molecular; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001952:Bridged-Ring Compounds; D006586:Hexanes; D047028:Macrocyclic Compounds; C431673:solanoeclepin A; D003035:Cobalt