title: [Esthesioneuroblastoma].
abstract: Esthesioneuroblastoma is an uncommon malignancy originating from olfactive epithelium. Men are more frequently affected than women. Nasal symptoms are the most common revealing signs. Immunohistochemistry helps diagnosis. There is no randomized trial evaluating treatment due to the low incidence of this tumor. Radiotherapy and surgery are the standard of care. Radiotherapy is benefic even in early stage disease. Chemotherapy is indicated in case of locally advanced or metastatic disease.
authors.affiliation: Centre hospitalier universitaire Habib Bourguiba, service de radiothérapie carcinologique, route el Aïn Km 0.5, 3029 Sfax, Tunisie.
authors.forename: Fatma
authors.initials: F
authors.lastname: Elloumi
authors.forename: Noureddine
authors.initials: N
authors.lastname: Boujelbene
authors.forename: Lilia
authors.initials: L
authors.lastname: Ghorbal
authors.forename: Nadia
authors.initials: N
authors.lastname: Boujelbene
authors.forename: Khaouthar
authors.initials: K
authors.lastname: Khanfir
authors.forename: René-Olivier
authors.initials: RO
authors.lastname: Mirimanoff
authors.forename: Jamel
authors.initials: J
authors.lastname: Daoud
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D018304:Esthesioneuroblastoma, Olfactory / Q000175:diagnosis / Q000473:pathology / Q000556:secondary / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D009296:Nasal Cavity / Q000473:pathology; D009669:Nose Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D011379:Prognosis; D011878:Radiotherapy / Q000379:methods; D035583:Rare Diseases / Q000175:diagnosis / Q000473:pathology / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents