title: Allelic polymorphic investigation of 21 autosomal short tandem repeat loci in a Chinese Bai ethnic group.
abstract: Population genetic data of 21 autosomal short tandem repeats (STRs) were obtained in a sample of 106 unrelated healthy individuals of Bai ethnic minority born in the Dali Bai Autonomous Prefecture in Yunnan Province. We observed 138 alleles with corresponding allelic frequencies ranging from 0.005 to 0.575. The genotypic frequency distributions at those STR loci were consistent with Hardy-Weinberg equilibrium (Bonferroni's correction was used for Hardy-Weinberg equilibrium tests). The combined probability of exclusion, power of discrimination, probability of matching value for all 21 STR loci were 0.9999975729, 0.999999999999999999872 and 1.28×10(-19), respectively. The population data in this study showed significant differences from the previously published population data of Tibetan and Salar groups in some loci.
authors.affiliation: School of Medicine, Xi'an Jiaotong University, Xi'an 710061, PR China.
authors.forename: Chun-mei
authors.initials: CM
authors.lastname: Shen
authors.forename: Hong-dan
authors.initials: HD
authors.lastname: Wang
authors.forename: Wen-juan
authors.initials: WJ
authors.lastname: Liu
authors.forename: Shuan-liang
authors.initials: SL
authors.lastname: Fan
authors.forename: Guang
authors.initials: G
authors.lastname: Yang
authors.forename: Hai-Xia
authors.initials: HX
authors.lastname: Qin
authors.forename: Tong
authors.initials: T
authors.lastname: Xie
authors.forename: Shao-bo
authors.initials: SB
authors.lastname: Li
authors.forename: Jiang-wei
authors.initials: JW
authors.lastname: Yan
authors.forename: Bo-feng
authors.initials: BF
authors.lastname: Zhu
mesh_terms: D002681:China; D016172:DNA Fingerprinting; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D015810:Linkage Disequilibrium; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic