title: Wilms' tumor with right heart extension: report of a post-chemotherapeutic fatality.
abstract: Wilms' tumor (WT) has a strong propensity to invade the vasculature in the form of tumor-thrombus, into the renal veins, and inferior vena cava and even into the right atrium. This cavo-atrial propagation does not alter the prognosis and pre-operative chemotherapy produces shrinkage to the extent of even disappearance of caval or atrial extensions. We present a case of sudden death due to hemorrhagic expansion of the intra-atrial component of WT, immediately after commencement of chemotherapy, an uncommon incident.
authors.affiliation: Department of Pathology, Seth G.S. Medical College, Mumbai, India.
authors.forename: Pradeep
authors.initials: P
authors.lastname: Vaideeswar
authors.forename: Jayashri P
authors.initials: JP
authors.lastname: Chaudhari
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002648:Child; D017809:Fatal Outcome; D005260:Female; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary*; D006470:Hemorrhage / Q000150:complications*; D006801:Humans; D009396:Wilms Tumor / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000970:Antineoplastic Agents