title: A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells.
abstract: A new ratiometric fluorescence probe E1 based on an excited-state intramolecular proton transfer (ESIPT) mechanism for detection of hydrogen sulfide (H(2)S) is reported. E1 responds to H(2)S quickly and showed a 30-fold fluorescence enhancement in 2 minutes. Moreover, E1 can detect H(2)S quantitatively with a detection limit as low as 0.12 μM in aqueous solution. Its potential for biological applications was confirmed by employing it for fluorescence imaging of H(2)S in living cells.
authors.affiliation: Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Xu
authors.forename: Lin
authors.initials: L
authors.lastname: Xu
authors.forename: Ji
authors.initials: J
authors.lastname: Zhou
authors.forename: Yufang
authors.initials: Y
authors.lastname: Xu
authors.forename: Weiping
authors.initials: W
authors.lastname: Zhu
authors.forename: Xuhong
authors.initials: X
authors.lastname: Qian
mesh_terms: D052160:Benzothiazoles / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006862:Hydrogen Sulfide / Q000032:analysis*; D010636:Phenols / Q000737:chemistry; D012996:Solutions; D013050:Spectrometry, Fluorescence
chemical_list: D052160:Benzothiazoles; D005456:Fluorescent Dyes; D010636:Phenols; D012996:Solutions; C579049:fluorescence probe E1; C070846:2-(2-hydroxyphenyl)benzothiazole; D006862:Hydrogen Sulfide