title: A ratiometric fluorescent on-off Zn2+ chemosensor based on a tripropargylamine pyrene azide click adduct.
abstract: A new, easy-to-prepare and highly selective pyrene-linked tris-triazole amine fluorescent chemosensor has been designed from tripropargylamine and pyrene azide using Cu(I)-catalyzed click chemistry. The fluorescence on-off sensor 1 is highly selective for Zn(2+) displaying a ratiometric change in emission. The relative intensity ratio of monomer to excimer fluorescence (M(376)/E(465)) of the sensor increases 80-fold upon the addition of 10 equiv of Zn(2+) ions (with a detection limit of 0.2 μM).
authors.affiliation: Laboratory of Bioorganic Chemistry and Chemical Biology, Center for Nanotechnology, Heisenbergstraße 11, 48149 Münster, Germany.
authors.forename: Sachin A
authors.initials: SA
authors.lastname: Ingale
authors.forename: Frank
authors.initials: F
authors.lastname: Seela
mesh_terms: D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D011721:Pyrenes / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*; D015032:Zinc / Q000737:chemistry*
chemical_list: D001386:Azides; D005456:Fluorescent Dyes; C579031:N,N-tris(((1-pyren-1-ylmethyl)-1H-1,2,3-triazol-4-yl)methyl)amine; D009942:Organometallic Compounds; D011721:Pyrenes; D014230:Triazoles; D003300:Copper; D015032:Zinc