title: Heme plane orientation dependent direct electron transfer of cytochrome c at SAMs/Au electrodes with different wettability.
abstract: It is proposed that direct electron transfer is dependent on the orientation of the heme plane in cytochrome c (cyt c) assembled on electrode surfaces. Orientation with the heme plane in cyt c parallel to the gold electrode surface favors the direct electron transfer, while vertical orientation of the heme plane makes the direct electron transfer difficult. A preferable electron transport pathway for cyt c is through the axial ligand (His-18) of the heme center rather than the porphyrin ring.
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
authors.forename: Gui-Xia
authors.initials: GX
authors.lastname: Wang
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: Bao
authors.forename: Min
authors.initials: M
authors.lastname: Wang
authors.forename: Xing-Hua
authors.initials: XH
authors.lastname: Xia
mesh_terms: D000327:Adsorption; D045304:Cytochromes c / Q000737:chemistry*; D004563:Electrochemistry; D004566:Electrodes; D006046:Gold / Q000737:chemistry*; D006418:Heme / Q000737:chemistry*; D013499:Surface Properties; D017155:Wettability
chemical_list: D006418:Heme; D006046:Gold; D045304:Cytochromes c