title: Extramedullary hematopoiesis involving uterus, fallopian tubes, and ovaries, mimicking bilateral tuboovarian abscesses.
abstract: Extramedullary hematopoiesis (EMH) is normal during fetal life, but after birth, the presence of EMH is considered to be abnormal. The most common sites for EMH are the liver, the spleen, and paraspinal regions of the thorax; however, it has been reported to involve virtually any organ or tissue. To our knowledge, this is the first reported case of EMH involving the entire upper genital tract, including the uterus, fallopian tubes, and ovaries. A 43-yr-old African American woman presented with a tender pelvic mass and a markedly elevated white blood cell count. Imaging was consistent with bilateral tuboovarian abscesses. Laparotomy and removal of uterus, tubes, and ovaries and bone marrow biopsy confirmed chronic myelogenous leukemia in the chronic phase and EMH in the cervix, endometrium, and ovaries, and no evidence of infection. We believe this to be the first reported case of EMH involving all organs of the upper genital tract presenting in a patient who has chronic myelogenous leukemia but not in blast crisis. This case illustrates the importance of a broad differential diagnosis when managing a patient with a pelvic mass and the value of a multidisciplinary team approach.
authors.affiliation: Departments of Obstetrics and Gynecology, Medical College of Wisconsin Affiliated Hospitals, Green Bay, WI, USA. anatlivs@gmail.com
authors.forename: Anna
authors.initials: A
authors.lastname: Palatnik
authors.forename: Raj
authors.initials: R
authors.lastname: Narayan
authors.forename: Matt
authors.initials: M
authors.lastname: Walters
mesh_terms: D000038:Abscess / Q000175:diagnosis / Q000473:pathology*; D000328:Adult; D003937:Diagnosis, Differential; D005184:Fallopian Tube Diseases / Q000175:diagnosis / Q000473:pathology*; D005187:Fallopian Tubes / Q000473:pathology; D005260:Female; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D010049:Ovarian Diseases / Q000175:diagnosis / Q000473:pathology*; D010053:Ovary / Q000473:pathology; D014599:Uterus / Q000473:pathology*