title: [Comparative study of the influence of succinate-containing preparations on mitochondrial respiration in rat brain cells].
abstract: It has been established by polarographic measurements that preparations containing succinate, such as cytoflavin (0.85 mM succinate), mexidol, and amtizol succinate (at a concentration of 0.85 mM) but not reamberin (0.045 mM succinate), nearly equally (by 35-45%) increase oxygen consumption in rat brain mitochondria. On the other hand, malonate - inhibitor of the respiratory complex II (succinate dehydrogenase) of mitochondrial chain suppressed the stimulating effect of these drugs.
authors.forename: V V
authors.initials: VV
authors.lastname: Iasnetsov
authors.forename: E P
authors.initials: EP
authors.lastname: Prosvirova
authors.forename: E G
authors.initials: EG
authors.lastname: Tsublova
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D001923:Brain Chemistry / Q000187:drug effects; D042963:Electron Transport Complex II / Q000378:metabolism*; D008297:Male; D008928:Mitochondria / Q000378:metabolism*; D051381:Rats; D013386:Succinates / Q000494:pharmacology*
chemical_list: D013386:Succinates; D042963:Electron Transport Complex II