title: Palladium-catalyzed ortho-alkoxylation of anilides via C-H activation.
abstract: A palladium-catalyzed ortho-alkoxylation of anilides with both primary and secondary alcohols via ligand-directed C-H activation has been explored. This alkoxylation promoted by catalytic methanesulfonic acid proceeds well at room temperature in most cases and affords aryl alkyl ethers in moderate to good yields.
authors.affiliation: CAS Key Laboratory of Soft Matter Chemistry, and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, PR China.
authors.forename: Tao-Shan
authors.initials: TS
authors.lastname: Jiang
authors.forename: Guan-Wu
authors.initials: GW
authors.lastname: Wang
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D000813:Anilides / Q000737:chemistry*; D002384:Catalysis; D004987:Ethers / Q000737:chemistry*; D006860:Hydrogen Bonding; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000438:Alcohols; D000813:Anilides; D004987:Ethers; D010165:Palladium