title: Early intervention for treatment and prevention of colorectal carcinomatosis: a plan for individualized care.
abstract: The benefits that are reported in patients who have carcinomatosis from colorectal cancer increase as the extent of disease within the abdomen and pelvis decreases. To optimize treatments that involve cytoreductive surgery and perioperative chemotherapy, early intervention is necessary. Strategies to improve the results of carcinomatosis treatments include second-look surgery and hyperthermic intraperitoneal chemotherapy in patients at high risk for recurrence. Alternatively, the use of hyperthermic intraperitoneal chemotherapy can be used to treat or prevent carcinomatosis at the time of primary colorectal cancer resection in selected patients.
authors.affiliation: Program in Peritoneal Surface Malignancy, Washington Cancer Institute, Washington, DC 20010, USA. Paul.Sugarbaker@medstar.net
authors.forename: Paul H
authors.initials: PH
authors.lastname: Sugarbaker
mesh_terms: D000465:Algorithms; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002277:Carcinoma / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D010478:Chemotherapy, Cancer, Regional Perfusion / Q000379:methods*; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D018450:Disease Progression; D061345:Early Medical Intervention; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007263:Infusions, Parenteral; D010347:Patient Care Planning; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D057285:Precision Medicine; D011379:Prognosis; D024162:Second-Look Surgery / Q000379:methods; D013997:Time Factors
chemical_list: D000970:Antineoplastic Agents