title: Long-term evolution of idiopathic lamellar macular holes and macular pseudoholes.
abstract: OBJECTIVE
  To analyze the natural evolution of idiopathic lamellar macular holes (LMH) and macular pseudoholes (MPH) in the long term, based on optical coherence tomography (OCT) configuration and on best corrected visual acuity (BCVA) evolution.
  
  
  METHODS
  A prospective, longitudinal study.
  
  
  METHODS
  We prospectively analyzed 108 eyes (67 left eyes and 41 right eyes) of 99 patients (55 female and 44 male) whose eyes had been diagnosed as having an MPH or an LMH on OCT examination.
  
  
  METHODS
  The following variables were assessed: BCVA; lens status; and hole size (diameter, residual foveal thickness, and perifoveal thickness) at baseline and at final examination.
  
  
  RESULTS
  The mean follow-up period was 31.07 ± 18.77 (12 to 84) months. The mean BCVA (logMAR) in the total group at baseline was 0.31 ± 0.25, and at final examination it was 0.22 ± 0.21 (p = 0.200). Moreover, we did not observe statistically significant differences regarding diameter, residual foveal thickness, or perifoveal thickness (p = 0.325).
  
  
  CONCLUSIONS
  Most idiopathic LMH and MPH do not progress anatomically and do not contribute to a significant diminution in visual acuity during the follow-up period.
authors.affiliation: Department of Ophthalmology, University Central Hospital of Asturias, Asturias, Spain. migarci@hotmail.es
authors.forename: Miriam
authors.initials: M
authors.lastname: García-Fernández
authors.forename: Joaquín Castro
authors.initials: JC
authors.lastname: Navarro
authors.forename: Alvaro Fernández-Vega
authors.initials: AF
authors.lastname: Sanz
authors.forename: Carmen González
authors.initials: CG
authors.lastname: Castaño
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012167:Retinal Perforations / Q000175:diagnosis* / Q000209:etiology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology*