title: Short sleep duration, complaints of vital exhaustion and perceived stress are prevalent among pregnant women with mood and anxiety disorders.
abstract: BACKGROUND
  Psychiatric disorders have been associated with sleep disorders in men and non-pregnant women, but little is known about sleep complaints and disorders among pregnant women with psychiatric disorders.
  
  
  METHODS
  A cohort of 1,332 women was interviewed during early pregnancy. We ascertained psychiatric diagnosis status and collect information about sleep duration, daytime sleepiness, vital exhaustion and perceived stress. Logistic regression procedures were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs).
  
  
  RESULTS
  Approximately 5.1% of the cohort (n=68) reported having a physician-diagnosis of mood or anxiety disorder before interview. Compared with women without a psychiatric diagnosis, the multivariable-adjusted OR (95% CI) for short sleep duration in early pregnancy (≤6 hours) were 1.95 (1.03-3.69). The corresponding OR (95%CI) for long sleep duration (≥9 hours) during early pregnancy was 1.13 (0.63-2.03). Women with psychiatric disorders had an increased risk of vital exhaustion (OR=2.41; 95%CI 1.46-4.00) and elevated perceived stress (OR=3.33; 95%CI 1.89-5.88). Observed associations were more pronounced among overweight/obese women.
  
  
  CONCLUSIONS
  Women with a psychiatric disorder were more likely to report short sleep durations, vital exhaustion and elevated perceived stress. Prospective studies are needed to more thoroughly explore factors that mediate the apparent mood/anxiety-sleep comorbidity among pregnant women.
authors.affiliation: Center for Perinatal Studies, Swedish Medical Center, 1124 Columbia Street, Suite 750, Seattle, Washington, USA. Chun-fang.Qiu@Swedish.org
authors.forename: Chunfang
authors.initials: C
authors.lastname: Qiu
authors.forename: Bizu
authors.initials: B
authors.lastname: Gelaye
authors.forename: Neway
authors.initials: N
authors.lastname: Fida
authors.forename: Michelle A
authors.initials: MA
authors.lastname: Williams
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000453:epidemiology / Q000523:psychology; D015331:Cohort Studies; D015897:Comorbidity; D005260:Female; D006801:Humans; D016015:Logistic Models; D019964:Mood Disorders / Q000453:epidemiology / Q000523:psychology; D016017:Odds Ratio; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000523:psychology; D011446:Prospective Studies; D012893:Sleep Wake Disorders / Q000453:epidemiology*; D013315:Stress, Psychological / Q000453:epidemiology*; D011795:Surveys and Questionnaires; D014861:Washington / Q000453:epidemiology; D055815:Young Adult