title: Accuracy of automatic detection of small-bowel mucosa by second-generation colon capsule endoscopy.
abstract: BACKGROUND
  Colon capsule endoscopy (CCE) is a noninvasive technique for the detection of colorectal lesions. However, for CCE to be offered as an out-of-clinic procedure, the system needs to automatically alert the patient when to ingest the laxative (booster).
  
  
  OBJECTIVE
  We tested the reliability of the automatic detection of the small-bowel (SB) mucosa and the subsequent alert for booster ingestion by the Data Recorder 3 (DR3) of the second-generation CCE (CCE-2).
  
  
  METHODS
  Retrospective analysis.
  
  
  METHODS
  Data from 120 consecutive cases of CCE-2 were analyzed for proper DR3 automatic detection of the capsule entering the SB to prompt the patient to ingest the laxative booster.
  
  
  METHODS
  Accuracy of the DR3 for detecting the SB mucosa.
  
  
  RESULTS
  The DR3 correctly identified the proper time for ingestion of the laxative (booster) in 118 of 120 cases, corresponding to a sensitivity of 98.3% (95% CI, 97%-100%). The median time difference between DR3 automatic SB detection to the observed entrance of the capsule into the SB was 3 minutes 30 seconds (interquartile range 2 minutes 35 seconds to 5 minutes 57 seconds).
  
  
  CONCLUSIONS
  Retrospective analysis.
  
  
  CONCLUSIONS
  The 98.3% sensitivity of the DR3 for automatic identification of the SB mucosa and subsequent alert for the first laxative (booster) ingestion paves the way for CCE-2 to be offered as an out-of-clinic procedure.
authors.affiliation: Division of Gastroenterology, Bikur Holim Hospital, Jerusalem, Israel.
authors.forename: Samuel
authors.initials: S
authors.lastname: Adler
authors.forename: Cesare
authors.initials: C
authors.lastname: Hassan
authors.forename: Yoav
authors.initials: Y
authors.lastname: Metzger
authors.forename: Yishai
authors.initials: Y
authors.lastname: Sompolinsky
authors.forename: Cristiano
authors.initials: C
authors.lastname: Spada
mesh_terms: D000328:Adult; D000368:Aged; D053705:Capsule Endoscopes; D053704:Capsule Endoscopy / Q000295:instrumentation* / Q000379:methods; D003113:Colonoscopy / Q000295:instrumentation* / Q000379:methods; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa; D007421:Intestine, Small; D054368:Laxatives / Q000008:administration & dosage*; D008297:Male; D050316:Medical Order Entry Systems; D008875:Middle Aged; D010710:Phosphates / Q000008:administration & dosage*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
chemical_list: D054368:Laxatives; D010710:Phosphates; C018279:sodium phosphate