title: Can live xPlane imaging of the in-plane view of interventricular septum be used to detect fetal conotruncal anomalies?
abstract: OBJECTIVE
  To evaluate the feasibility of live xPlane imaging visualizing the in-plane view of IVS in the screening of the fetal conotruncal anomalies.
  
  
  METHODS
  One hundred and fifty-two consecutive normal singleton fetuses and forty-eight fetal cardiac defects (27 conotruncal and 21 non-conotruncal cases), were enrolled in this study. The in-plane view of IVS was firstly acquired with live xPlane imaging and then judged whether it is normal or not by one operator. The focus was put on observing the relationship of pulmonary artery and aorta. The comparison between conotruncal and non-conotruncal anomalies in demonstrating the relationship of pulmonary artery and aorta was performed.
  
  
  RESULTS
  There were 27 cases of conotruncal anomalies enrolled in this study and 19 cases (70.4%) had the abnormal relationship of aorta and pulmonary artery in the in-plane view of IVS. In 21 cases of non-conotruncal CHDs, however, there were only 5 cases (23.8%) had the abnormal relationship in the in-plane view of IVS (p < 0.001).
  
  
  CONCLUSIONS
  Live xPlane imaging of the in-plane view of IVS is feasible to detect the fetal conotruncal anomalies, which may potentially be a useful tool for the non-experienced operators to screen the fetal conotruncal anomalies.
authors.affiliation: Department of Obstetrics and Gynaecology, Fetal Medicine Unit, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong. xiongyi.xiongyi@163.com
authors.forename: Yi
authors.initials: Y
authors.lastname: Xiong
authors.forename: Tao
authors.initials: T
authors.lastname: Liu
authors.forename: Han Jing
authors.initials: HJ
authors.lastname: Gan
authors.forename: Ying
authors.initials: Y
authors.lastname: Wu
authors.forename: Jing Feng
authors.initials: JF
authors.lastname: Xu
authors.forename: Yuen Ha
authors.initials: YH
authors.lastname: Ting
authors.forename: Tak Yeung
authors.initials: TY
authors.lastname: Leung
authors.forename: Tze Kin
authors.initials: TK
authors.lastname: Lau
mesh_terms: D000328:Adult; D001011:Aorta / Q000000981:diagnostic imaging / Q000196:embryology; D005260:Female; D005318:Fetal Heart / Q000000981:diagnostic imaging; D005865:Gestational Age; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging*; D006801:Humans; D011247:Pregnancy; D011651:Pulmonary Artery / Q000000981:diagnostic imaging / Q000196:embryology; D016216:Ultrasonography, Prenatal / Q000379:methods*; D054088:Ventricular Septum / Q000000981:diagnostic imaging* / Q000196:embryology*