title: Sarcoidosis complicated with major pulmonary artery obstruction and stenosis.
abstract: A 34-year-old woman with bilateral pulmonary infiltrates was diagnosed with sarcoidosis. She refused corticosteroid treatment despite a worsening of the pulmonary infiltrate, and thereafter developed dyspnea following hemoptysis 6 years later. The upper lobe branches of the pulmonary artery were obstructed and the left main pulmonary artery was narrowed by mediastinal soft tissue, thus complications of granulomatous mediastinitis and fibrosing mediastinitis were suspected. The mediastinal soft tissue regressed, following the administration of corticosteroids, whereas the vascular obstruction and narrowing remained unchanged. Although the obstruction or stenosis of major pulmonary vessels is rare in sarcoidosis, such potential developments should be considered when mediastinal soft tissue appears in follow-up examinations.
authors.affiliation: Department of Respiratory Medicine, Japanese Red Cross Kyoto Daiichi Hospital, Japan. kouichi-hasegawa@kyoto1-jrc.org
authors.forename: Koichi
authors.initials: K
authors.lastname: Hasegawa
authors.forename: Seiko
authors.initials: S
authors.lastname: Ohno
authors.forename: Mai
authors.initials: M
authors.lastname: Takada
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ogino
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Shiotsu
authors.forename: Chieko
authors.initials: C
authors.lastname: Takumi
authors.forename: Noriya
authors.initials: N
authors.lastname: Hiraoka
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Handa
authors.forename: Sonoko
authors.initials: S
authors.lastname: Nagai
mesh_terms: D000328:Adult; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology*; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use; D011651:Pulmonary Artery / Q000000981:diagnostic imaging / Q000473:pathology*; D012507:Sarcoidosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D011239:Prednisolone