title: [A case of mucosal Schwann cell hamartoma].
abstract: A 40-year-old man was referred to our hospital because of a positive fecal occult blood test. Colonoscopy revealed many small whitish nodules in the mucosa of the sigmoid colon. Specimens endoscopically resected from the lesions revealed spindle cell proliferation in the lamina propria. Immunohistochemical study revealed strong and diffuse positivity for S-100 protein. Results of staining for neurofilament protein and epithelial membrane antigen were negative. The neurogenic tumors were diagnosed as mucosal Schwann cell hamartoma. No clinical features of multiple endocrine neoplasia type 2B or neurofibromatosis type 1 were found in the present case.
authors.affiliation: Department of Gastroenterology, JA Onomichi General Hospital, Japan.
authors.forename: Shintaro
authors.initials: S
authors.lastname: Sagami
authors.forename: Akira
authors.initials: A
authors.lastname: Fukumoto
authors.forename: Mio
authors.initials: M
authors.lastname: Amano
authors.forename: Kentaro
authors.initials: K
authors.lastname: Yamao
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Iiboshi
authors.forename: Seiji
authors.initials: S
authors.lastname: Onogawa
authors.forename: Naomichi
authors.initials: N
authors.lastname: Hirano
authors.forename: Keiji
authors.initials: K
authors.lastname: Hanada
authors.forename: Hajime
authors.initials: H
authors.lastname: Amano
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Hino
authors.forename: Shuji
authors.initials: S
authors.lastname: Yonehara
mesh_terms: D000328:Adult; D006222:Hamartoma / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D012583:Schwann Cells / Q000473:pathology; D012811:Sigmoid Neoplasms / Q000473:pathology*