title: [Hypothermia at admission increases the risk of pulmonary contusion's infection in intubated trauma patients].
abstract: OBJECTIVE
  Pulmonary contusion (PC) is common in cases of polytrauma. The aim of this study was to perform a multivariate analysis of risk factors associated with the occurrence of infection in PC and analyze the microbiological epidemiology.
  
  
  METHODS
  All patients with PC admitted to the intensive care unit (ICU) between January 2002 and December 2006 were included in this retrospective observational study. Patients with penetrating thoracic trauma or those who died in the 48hours following admission to hospital were excluded. Diagnosis of bacterial infection in PC was performed if hyperthermia was associated with a positive quantitative culture (103 colony forming units/mL) on the bronchial sample. Univariate analysis provided statistical difference between variables that were integrated in the multivariate analysis model. Multivariate analysis was then performed to determine the risk factors of bacterial infection in PC.
  
  
  RESULTS
  One hundred and seventeen patients were included. The incidence of bacterial infection in PC was 33.3% (39 patients). The most frequently encountered bacteria were Haemophilus sp., Staphylococcus aureus, Enterobacteriaceae, Pseudomonas sp. and Streptococcus sp. According to multivariate analysis, the existence of hypothermia at hospital admission increased the risk of PC infection (OR=2.61; IC 95% [4.2-13.3]).
  
  
  CONCLUSIONS
  In conclusion, PC was infected in 33.3% of cases. The existence of hypothermia was identified as a risk factor. A prospective study is warranted to confirm these results.
authors.affiliation: Pôle réanimations-anesthésie-Samu, CHU Charles-Nicolle, 1, rue de Germont, 76031 Rouen cedex, France. vincent.royon@chu-rouen.fr
authors.forename: V
authors.initials: V
authors.lastname: Royon
authors.forename: P-G
authors.initials: PG
authors.lastname: Guitard
authors.forename: C
authors.initials: C
authors.lastname: Abriou
authors.forename: N
authors.initials: N
authors.lastname: Frebourg
authors.forename: J-F
authors.initials: JF
authors.lastname: Menard
authors.forename: T
authors.initials: T
authors.lastname: Clavier
authors.forename: B
authors.initials: B
authors.lastname: Dureuil
authors.forename: B
authors.initials: B
authors.lastname: Veber
mesh_terms: D000328:Adult; D001424:Bacterial Infections / Q000453:epidemiology* / Q000209:etiology*; D003288:Contusions / Q000150:complications*; D005260:Female; D006801:Humans; D007035:Hypothermia / Q000150:complications*; D007442:Intubation, Intratracheal; D055370:Lung Injury / Q000150:complications*; D008297:Male; D015999:Multivariate Analysis; D012189:Retrospective Studies; D012307:Risk Factors