title: Fumagillin-induced aseptic meningoencephalitis in a kidney transplant recipient with microsporidiosis.
abstract: Microsporidiosis is an opportunistic infection in organ transplant recipients and patients with other cellular immunodeficiency. Fumagillin is an effective treatment against Enterocytozoon bieneusi, one of the two main species causing the microsporidiosis involved in human diseases. We report the first case, to our knowledge, of a probable drug-induced aseptic meningoencephalitis, after administration of fumagillin in a kidney transplant recipient with microsporidiosis.
authors.affiliation: Internal Medicine, Caen University Hospital, Caen, France. alexandra.audemard@hotmail.fr
authors.forename: A
authors.initials: A
authors.lastname: Audemard
authors.forename: M L
authors.initials: ML
authors.lastname: Le Bellec
authors.forename: L
authors.initials: L
authors.lastname: Carluer
authors.forename: S
authors.initials: S
authors.lastname: Dargère
authors.forename: R
authors.initials: R
authors.lastname: Verdon
authors.forename: C
authors.initials: C
authors.lastname: Castrale
authors.forename: T
authors.initials: T
authors.lastname: Lobbedez
authors.forename: B
authors.initials: B
authors.lastname: Hurault de Ligny
mesh_terms: D000935:Antifungal Agents / Q000009:adverse effects*; D003510:Cyclohexanes / Q000009:adverse effects* / Q000627:therapeutic use; D005231:Fatty Acids, Unsaturated / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation / Q000009:adverse effects*; D008590:Meningoencephalitis / Q000209:etiology*; D016881:Microsporidiosis / Q000188:drug therapy*; D008875:Middle Aged; D012717:Sesquiterpenes / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D003510:Cyclohexanes; D005231:Fatty Acids, Unsaturated; D012717:Sesquiterpenes; C026211:fumagillin