title: Advances in immunotherapy for food allergy.
abstract: Food allergy is a life-threatening allergic disease that is increasing in prevalence with no approved curative therapy. Standard treatment of food allergy is limited to avoidance of the allergen and supportive management of allergic symptoms and anaphylaxis. Current research, however, has been focused on developing therapy that can modify the allergic immune response in both allergen-specific and non-specific methods. This review will provide an overview of these methods including oral immunotherapy, sublingual immunotherapy, epicutaneous immunotherapy, modified food protein vaccines, anti-IgE monoclonal antibody adjuvant therapy, Chinese herbs, and helminth therapy.
authors.affiliation: Division of Allergy and Immunology, Department of Pediatrics, Duke University School of Medicine, Durham, North Carolina 27710, USA.
authors.forename: Yamini V
authors.initials: YV
authors.lastname: Virkud
authors.forename: Brian P
authors.initials: BP
authors.lastname: Vickery
mesh_terms: D000485:Allergens / Q000276:immunology; D000818:Animals; D000911:Antibodies, Monoclonal / Q000737:chemistry; D003888:Desensitization, Immunologic / Q000379:methods; D005512:Food Hypersensitivity / Q000276:immunology / Q000628:therapy*; D006376:Helminths / Q000378:metabolism; D006801:Humans; D007107:Immune System; D007073:Immunoglobulin E / Q000737:chemistry; D007167:Immunotherapy / Q000379:methods* / Q000639:trends*; D008516:Medicine, Chinese Traditional; D008892:Milk; D010063:Ovum; D014612:Vaccines / Q000737:chemistry
chemical_list: D000485:Allergens; D000911:Antibodies, Monoclonal; D014612:Vaccines; D007073:Immunoglobulin E