title: Bifidobacterium asteroides PRL2011 genome analysis reveals clues for colonization of the insect gut.
abstract: Bifidobacteria are known as anaerobic/microaerophilic and fermentative microorganisms, which commonly inhabit the gastrointestinal tract of various animals and insects. Analysis of the 2,167,301 bp genome of Bifidobacterium asteroides PRL2011, a strain isolated from the hindgut of Apis mellifera var. ligustica, commonly known as the honey bee, revealed its predicted capability for respiratory metabolism. Conservation of the latter gene clusters in various B. asteroides strains enforces the notion that respiration is a common metabolic feature of this ancient bifidobacterial species, which has been lost in currently known mammal-derived Bifidobacterium species. In fact, phylogenomic based analyses suggested an ancient origin of B. asteroides and indicates it as an ancestor of the genus Bifidobacterium. Furthermore, the B. asteroides PRL2011 genome encodes various enzymes for coping with toxic products that arise as a result of oxygen-mediated respiration.
authors.affiliation: Alimentary Pharmabiotic Centre and Department of Microbiology, Bioscience Institute, National University of Ireland, Cork, Ireland.
authors.forename: Francesca
authors.initials: F
authors.lastname: Bottacini
authors.forename: Christian
authors.initials: C
authors.lastname: Milani
authors.forename: Francesca
authors.initials: F
authors.lastname: Turroni
authors.forename: Borja
authors.initials: B
authors.lastname: Sánchez
authors.forename: Elena
authors.initials: E
authors.lastname: Foroni
authors.forename: Sabrina
authors.initials: S
authors.lastname: Duranti
authors.forename: Fausta
authors.initials: F
authors.lastname: Serafini
authors.forename: Alice
authors.initials: A
authors.lastname: Viappiani
authors.forename: Francesco
authors.initials: F
authors.lastname: Strati
authors.forename: Alberto
authors.initials: A
authors.lastname: Ferrarini
authors.forename: Massimo
authors.initials: M
authors.lastname: Delledonne
authors.forename: Bernard
authors.initials: B
authors.lastname: Henrissat
authors.forename: Pedro
authors.initials: P
authors.lastname: Coutinho
authors.forename: Gerald F
authors.initials: GF
authors.lastname: Fitzgerald
authors.forename: Abelardo
authors.initials: A
authors.lastname: Margolles
authors.forename: Douwe
authors.initials: D
authors.lastname: van Sinderen
authors.forename: Marco
authors.initials: M
authors.lastname: Ventura
mesh_terms: D000818:Animals; D001644:Bifidobacterium / Q000145:classification / Q000235:genetics* / Q000378:metabolism; D016000:Cluster Analysis; D041981:Gastrointestinal Tract / Q000382:microbiology*; D020869:Gene Expression Profiling; D015964:Gene Expression Regulation, Bacterial; D023061:Gene Order; D014644:Genetic Variation; D016680:Genome, Bacterial; D007313:Insecta / Q000382:microbiology*; D010101:Oxygen Consumption; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S; D017422:Sequence Analysis, DNA
chemical_list: D012336:RNA, Ribosomal, 16S