title: Kikuchi-Fujimoto disease with cutaneous presentation in a patient with subacute cutaneous lupus erythematosus.
abstract: We report the case of a 45-year-old female patient previously diagnosed with subacute cutaneous lupus erythematosus who presented with a one-week history of fever, tender erythematous nodules on her limbs, and palpable lymphadenopathy. Two incisional biopsies showed histiocytic infiltrates with abundant nuclear debris in the dermis and at the dermosubcutaneous junction with absence of neutrophils, characteristic of Kikuchi-Fujimoto disease (KFD). The dermatologic and dermopathologic details of KFD are very heterogeneous and yet poorly described. We have reviewed the literature regarding KFD cases reported with cutaneous involvement trying to assess the skin features of the KFD or histiocytic necrotizing lymphadenitis.
authors.affiliation: Department of Dermatology, Westmead Hospital, Westmead, New South Wales, Australia.
authors.forename: Julieta
authors.initials: J
authors.lastname: Ruiz Beguerie
authors.forename: Pablo
authors.initials: P
authors.lastname: Fernandez Penas
authors.forename: Raghwa
authors.initials: R
authors.lastname: Sharma
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D004359:Drug Therapy, Combination; D005260:Female; D006644:Histiocytes / Q000187:drug effects; D020042:Histiocytic Necrotizing Lymphadenitis / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D008178:Lupus Erythematosus, Cutaneous / Q000188:drug therapy / Q000473:pathology*; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D009288:Naproxen / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D006886:Hydroxychloroquine; D009288:Naproxen; D011241:Prednisone