title: Overview of glutathione function and metabolism.
abstract: Glutathione is a key player in reduction processes in the cell. It is responsible for maintaining thiol groups of intracellular proteins by providing reducing power for cysteine, dihydolipoate, CoA, ascorbate, and vitamin E. It also plays a role in reduction of NTPs to dNTPs. Glutathione is also involved in detoxification of endogenous and exogenous compounds, participates in the synthesis of leukotrienes and prostaglandins, serves as a cofactor for various enzymes, stores and transports cysteine, and may be involved in cell cycle regulation and thermotolerance.
authors.affiliation: Oregon State University, Corvallis, Oregon, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Will
mesh_terms: D000818:Animals; D005978:Glutathione / Q000096:biosynthesis / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008928:Mitochondria / Q000378:metabolism
chemical_list: D005978:Glutathione