title: [Dosage of cadmium and lead in human blood by anodic stripping voltammetry].
abstract: The objective is the determination of the conditions operating optimal to determine the concentration of the cadmium and the lead dissolved in the human blood. An electroanalytical method has been developed for the determination of lead and cadmium in whole blood by differential pulse anodic stripping voltammetry (DPASV) on a hanging mercury drop electrode (HMDE). The best conditions were found to be electrolyte support perchloric acid 0.02 M, the accumulation potential is -900 mV, and the accumulation time is 320 s. The obtained limits of detection are equal to 0.46 and 0.08 ng/mL respectively for the lead and the cadmium. The developed method was validated by the analysis of reference materials certified by total blood.
authors.affiliation: Laboratoire d'électrochimie et chimie analytique, Département de chimie, Faculté des sciences, Université Abou Bekr Belkaid, Tlemcen, Algérie. att.tarik@gmail.com
authors.forename: Tarik
authors.initials: T
authors.lastname: Attar
authors.forename: Yahia
authors.initials: Y
authors.lastname: Harek
authors.forename: Nouria
authors.initials: N
authors.lastname: Dennouni-Medjati
authors.forename: Larabi
authors.initials: L
authors.lastname: Lahcen
mesh_terms: D001774:Blood Chemical Analysis / Q000379:methods*; D002104:Cadmium / Q000032:analysis* / Q000097:blood; D002105:Cadmium Poisoning / Q000097:blood / Q000175:diagnosis; D004563:Electrochemistry / Q000379:methods; D004566:Electrodes; D004573:Electrolytes / Q000494:pharmacology; D006801:Humans; D007854:Lead / Q000032:analysis* / Q000097:blood; D007855:Lead Poisoning / Q000097:blood / Q000175:diagnosis; D011048:Polarography / Q000379:methods; D011934:Reagent Strips; D013997:Time Factors
chemical_list: D004573:Electrolytes; D011934:Reagent Strips; D002104:Cadmium; D007854:Lead