title: Estimation of the concordance correlation coefficient for repeated measures using SAS and R.
abstract: The concordance correlation coefficient is one of the most common approaches used to assess agreement among different observers or instruments when the outcome of interest is a continuous variable. A SAS macro and R package are provided here to estimate the concordance correlation coefficient (CCC) where the design of the data involves repeated measurements by subject and observer. The CCC is estimated using U-statistics (UST) and variance components (VC) approaches. Confidence intervals and standard errors are reported along with the point estimate of the CCC. In the case of the VC approach, the linear mixed model output and variance components estimates are also provided. The performance of each function is shown by means of some examples with real data sets.
authors.affiliation: Biostatistics Unit, Public Health Department, University of Barcelona, Barcelona, Spain. jlcarrasco@ub.edu
authors.forename: Josep L
authors.initials: JL
authors.lastname: Carrasco
authors.forename: Brenda R
authors.initials: BR
authors.lastname: Phillips
authors.forename: Josep
authors.initials: J
authors.lastname: Puig-Martinez
authors.forename: Tonya S
authors.initials: TS
authors.lastname: King
authors.forename: Vernon M
authors.initials: VM
authors.lastname: Chinchilli
mesh_terms: D000465:Algorithms; D019540:Area Under Curve; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000379:methods / Q000592:standards*; D003198:Computer Simulation; D016001:Confidence Intervals; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D016014:Linear Models; D015588:Observer Variation; D015203:Reproducibility of Results; D012984:Software; D013223:Statistics as Topic
chemical_list: D006854:Hydrocortisone