title: [Multivariate prediction of breeding values for canine hip and elbow dysplasia as well as humeral osteochondrosis in the Bernese mountain dog].
abstract: The aim of this study was the multivariate prediction of breeding values for canine hip dysplasia (CHD), elbow dysplasia (ED) and humeral osteochondrosis (OCD) for Bernese mountain dogs of the Schweizer Sennenhund-Verein für Deutschland e. V. (SSV). For the analysis the pedigrees of eight generations and radiographic screening results of the birth cohorts from 1995-2008 were used. The number of dogs with scores for CHD was 5513, for ED 5175 and OCD 1240. Breeding values were multivariately predicted using a mixed linear model for CHD, ED and OCD as well as for the occurrence of a fragmented coronoid process of the medial ulna (FCP) and the ED-score without FCP. The pedigree breeding value (eRZWp) which is used as the selection criterion reached a reliability to predict the phenotype of the offspring at 2.8-2.9% for CHD, 2.9% for ED, 1.1% for ED without FCP, 1.8% for FCP and 0.8-1.3% for OCD. The reason for the low predictive value of the eRZW(P) is caused by the very high influence of the own performance of the animal and the very uniform distribution of contributions of the breeding values of the relatives.These results indicate that even a multivariate prediction of breeding values does not lead to a faster progress in breeding against CHD and ED, however, does allow breeding against OCD in the Bernese mountain dog. In comparison to phenotypic selection, there is some improvement in the selection response when using breeding values. Due to the general low predictive power of breeding values better approaches for selection of future breeding animals are urgently warranted to achieve improvements in breeding Bernese mountain dogs.
authors.affiliation: Institut für Tierzucht und Vererbungsforschung, Stiftung Tierärztliche Hochschule Hannover.
authors.forename: Peter
authors.initials: P
authors.lastname: Hartmann
authors.forename: Kathrin-Friederike
authors.initials: KF
authors.lastname: Stock
authors.forename: Ottmar
authors.initials: O
authors.lastname: Distl
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D001947:Breeding; D004283:Dog Diseases / Q000453:epidemiology*; D004285:Dogs; D005260:Female; D006619:Hip Dysplasia, Canine / Q000453:epidemiology*; D008297:Male; D055034:Osteochondrosis / Q000453:epidemiology / Q000662:veterinary*; D010641:Phenotype