title: Socket grafting with calcium phosphosilicate alloplast putty: a histomorphometric evaluation.
abstract: BACKGROUND
  Socket grafting with a bone graft substitute immediately after extraction is essential to preserve the ridge architecture for implant placement. Several bone graft substitutes have been tested for their ability to effectively regenerate osseous tissue in the sockets. Evidence suggests that socket bone typically regenerates during a period of 6 to 8 months or longer, depending on several factors including the original ridge dimensions, type of graft, and the overall systemic health of the individual. The purpose of this study is to histologically evaluate the bone regeneration potential of a novel synthetic calcium phosphosilicate putty (CPS) graft substitute.
  
  
  METHODS
  After extraction of the involved teeth, CPS putty graft was placed, and the sockets were covered with a collagen plug. Cores were taken from 20 patients for histological evaluation prior to implant placement. Ten cores were processed decalcified with hematoxylin and eosin (H&E) stain and the remaining 10 were processed undecalcified. Histomorphometric data obtained from both sets is presented.
  
  
  RESULTS
  Histomorphometric analysis revealed an average vital bone content of 49.5 (± 20.7). A residual graft content of 4.3% (± 7.8) was observed following a healing time of 4.9 (± 0.8) months.
  
  
  CONCLUSIONS
  Clinical and histomorphometric data suggests that CPS putty is a good choice for socket bone regeneration in implant-related surgeries.
authors.forename: Lanka
authors.initials: L
authors.lastname: Mahesh
authors.forename: Maurice A
authors.initials: MA
authors.lastname: Salama
authors.forename: Gregori M
authors.initials: GM
authors.lastname: Kurtzman
authors.forename: Frederic P C
authors.initials: FP
authors.lastname: Joachim
mesh_terms: D000328:Adult; D000368:Aged; D001861:Bone Regeneration / Q000187:drug effects*; D018786:Bone Substitutes / Q000627:therapeutic use*; D002130:Calcium Phosphates / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017640:Silicates / Q000627:therapeutic use; D014081:Tooth Extraction; D020390:Tooth Socket / Q000601:surgery*
chemical_list: D018786:Bone Substitutes; D002130:Calcium Phosphates; D017640:Silicates