title: Clinical and metabolic evaluation of one-stage, full-mouth, ultrasonic debridement as a therapeutic approach for uncontrolled type 2 diabetic patients with periodontitis.
abstract: OBJECTIVE
  To evaluate the therapeutic potential of one-stage, full-mouth, ultrasonic debridement (FMUD) as a treatment for type 2 diabetic patients with generalized severe chronic periodontitis.
  
  
  METHODS
  Sixteen patients diagnosed with generalized severe chronic periodontitis and type 2 diabetes mellitus were allocated to the diabetic group; another 15 subjects with periodontitis but without metabolic disorders were placed in the nondiabetic group. Both groups were treated using the FMUD protocol, a unique 45-minute session of ultrasonic debridement of all sites presenting periodontal disease. Patients were analyzed for the following parameters: plaque and bleeding indices, gingival recession, probing depth, and clinical attachment level. Further, diabetic subjects were assessed using fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c) tests. Patients were evaluated at 3 and 6 months for all parameters. ANOVA and the Tukey test were used for data analysis (P < .05).
  
  
  RESULTS
  Both groups showed improved periodontal health after treatment. There were no significant differences between the groups for any of the parameters assessed (P > .05). Diabetic subjects treated with FMUD had a clinical response similar to that of nondiabetic subjects at all pocket depths. No adverse effects or medical disturbances were observed in either group during treatment. FPG and HbA1c levels remained unaltered after treatment.
  
  
  CONCLUSIONS
  Within the limitations of this study, FMUD promoted clinical improvements in patients with type 2 uncontrolled diabetes and generalized severe chronic periodontitis.
authors.affiliation: Periodontics Division, Paulista University, São Paulo, Brazil. cirano@unip.com.br
authors.forename: Fabiano Ribeiro
authors.initials: FR
authors.lastname: Cirano
authors.forename: Claudia
authors.initials: C
authors.lastname: Pera
authors.forename: Paulo
authors.initials: P
authors.lastname: Ueda
authors.forename: Renato Correa Viana
authors.initials: RC
authors.lastname: Casarin
authors.forename: Fernanda Vieira
authors.initials: FV
authors.lastname: Ribeiro
authors.forename: Suzana Peres
authors.initials: SP
authors.lastname: Pimentel
authors.forename: Marcio Zaffalon
authors.initials: MZ
authors.lastname: Casati
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001786:Blood Glucose / Q000032:analysis; D055113:Chronic Periodontitis / Q000150:complications* / Q000378:metabolism / Q000628:therapy*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000378:metabolism; D004311:Double-Blind Method; D005260:Female; D005889:Gingival Recession / Q000150:complications; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D057747:Periodontal Debridement / Q000379:methods*; D010512:Periodontal Index; D018709:Statistics, Nonparametric; D014464:Ultrasonic Therapy
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin