title: Dengue outbreaks in high-income area, Kaohsiung City, Taiwan, 2003-2009.
abstract: Kaohsiung City, a modern metropolis of 1.5 million persons, has been the focus of dengue virus activity in Taiwan for several decades. The aim of this study was to provide a temporal and spatial description of dengue virus epidemiology in Kaohsiung City by using data for all laboratory-confirmed dengue cases during 2003-2009. We investigated age- and sex-dependent incidence rates and the spatiotemporal patterns of all cases confirmed through passive or active surveillance. Elderly persons were at particularly high risk for dengue virus-related sickness and death. Of all confirmed cases, ≈75% were detected through passive surveillance activities; case-patients detected through active surveillance included immediate family members, neighbors, and colleagues of confirmed case-patients. Changing patterns of case clustering could be due to the effect of unmeasured environmental and demographic factors.
authors.affiliation: University of Copenhagen, Copenhagen, Denmark. chlin1983@gmail.com
authors.forename: Chia-Hsien
authors.initials: CH
authors.lastname: Lin
authors.forename: Karin L
authors.initials: KL
authors.lastname: Schiøler
authors.forename: Martin R
authors.initials: MR
authors.lastname: Jepsen
authors.forename: Chi-Kung
authors.initials: CK
authors.lastname: Ho
authors.forename: Shu-Hua
authors.initials: SH
authors.lastname: Li
authors.forename: Flemming
authors.initials: F
authors.lastname: Konradsen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003715:Dengue / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D003716:Dengue Virus / Q000235:genetics* / Q000302:isolation & purification; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance / Q000379:methods; D012959:Socioeconomic Factors; D013029:Space-Time Clustering; D062211:Spatio-Temporal Analysis; D013624:Taiwan / Q000453:epidemiology; D014505:Urban Population / Q000706:statistics & numerical data*; D055815:Young Adult