title: Occurrence and exposure assessment of aflatoxins in Catalonia (Spain).
abstract: The main objective of this study was to assess the exposure of Catalonian (Spain) population to AFs. Thus, two sub-objectives were considered: (1) to assess the occurrence of AFs in food marketed in Catalonia, and (2) to assess the consumption of those foods susceptible to AFs contamination by Catalonian population. AFs were analysed in a total of 603 samples considering special commodities as free-gluten, ethnic or baby foods. Analytical method consisted of an extraction and clean-up of aflatoxins step using immunoaffinity columns, and determination by HPLC with post-column photochemical derivatization and fluorescence detection. Food dietary intake was assessed using a food frequency questionnaire, administered to 1387 individuals by trained interviewers. Contamination and consumption raw datasets were combined by means of a direct method and a stochastic method, building the pseudo-parametric bootstrap confidence intervals of the main outputs. Margins of exposure (MoE) and cancer incidence were estimated for the different collectives. The highest percentages of positive samples were found in red pepper, pistachios and peanuts. Considering our results, the most exposed group was the celiac sufferer collective followed by the adolescents; however health concern should not be expected in the population groups.
authors.affiliation: Applied Mycology Unit, Food Technology Department, University of Lleida, XaRTA-UTPV, Lleida, Spain. gcano@tecal.udl.cat
authors.forename: G
authors.initials: G
authors.lastname: Cano-Sancho
authors.forename: V
authors.initials: V
authors.lastname: Sanchis
authors.forename: S
authors.initials: S
authors.lastname: Marín
authors.forename: A J
authors.initials: AJ
authors.lastname: Ramos
mesh_terms: D000293:Adolescent; D000328:Adult; D000348:Aflatoxins / Q000032:analysis* / Q000633:toxicity*; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004032:Diet; D004781:Environmental Exposure; D005260:Female; D005506:Food Contamination / Q000032:analysis*; D006801:Humans; D007223:Infant; D007225:Infant Food; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D013030:Spain; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D000348:Aflatoxins