title: Simple pyrazoline and pyrazole "turn on" fluorescent sensors selective for Cd2+ and Zn2+ in MeCN.
abstract: An efficient two-step synthesis of pyrazoline ligand  is described which is an effective "turn on" fluorescent sensor for Cd(2+) in MeCN. Oxidation to the corresponding pyrazole ligand  creates a "turn on" fluorescent sensor now selective for Zn(2+) and able to distinguish it from Cd(2+).
authors.affiliation: Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath, BA2 7AY, UK.
authors.forename: Alexander
authors.initials: A
authors.lastname: Ciupa
authors.forename: Mary F
authors.initials: MF
authors.lastname: Mahon
authors.forename: Paul A
authors.initials: PA
authors.lastname: De Bank
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Caggiano
mesh_terms: D000097:Acetonitriles / Q000737:chemistry; D002104:Cadmium / Q000032:analysis*; D002413:Cations, Divalent / Q000032:analysis; D005456:Fluorescent Dyes / Q000737:chemistry*; D008958:Models, Molecular; D010084:Oxidation-Reduction; D011720:Pyrazoles / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013050:Spectrometry, Fluorescence / Q000379:methods; D015032:Zinc / Q000032:analysis*
chemical_list: D000097:Acetonitriles; D002413:Cations, Divalent; D005456:Fluorescent Dyes; D011720:Pyrazoles; D002104:Cadmium; D015032:Zinc