title: Xanthomatous hyperplastic polyps of the stomach: clinicopathologic study of 5 patients with polypoid gastric lesions showing combined features of gastric xanthelasma and hyperplastic polyp.
abstract: Gastric xanthelasmas are uncommon benign lesions that are macroscopically well-demarcated yellow or yellow-white plaques and are microscopically formed by collections of foamy macrophages. Because gastric hyperplastic polyps may rarely be associated with xanthelasma, we aimed to report 5 cases of combined lesions showing features of gastric xanthelasma and hyperplastic polyps observed over the past 3 years at our institution among 4497 patients who underwent gastric endoscopy. The patients were 3 men and 2 women aged 45 to 78 years. The lesions were located in oxyntic mucosa, except one in the antrum, and measured 2 to 6 mm. Three patients showed associated chronic gastritis; none showed evidence of Helicobacter pylori infection. Combined lesions of hyperplastic polyp with xanthelasma appear to have an association with chronic gastritis, and the lipid accumulation may be the cause of hyperplasia in the overlying mucosa.
authors.affiliation: Department of Pathology, İstanbul Bilim University, Faculty of Medicine, Turkey. nuraybs@gmail.com
authors.forename: Nuray
authors.initials: N
authors.lastname: Bassullu
authors.forename: Ilknur
authors.initials: I
authors.lastname: Turkmen
authors.forename: Suleyman
authors.initials: S
authors.lastname: Uraz
authors.forename: Pinar
authors.initials: P
authors.lastname: Yagiz Korkmaz
authors.forename: Resat
authors.initials: R
authors.lastname: Memisoglu
authors.forename: Orhan Sami
authors.initials: OS
authors.lastname: Gultekin
authors.forename: Gulen
authors.initials: G
authors.lastname: Bulbul Dogusoy
mesh_terms: D000368:Aged; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005748:Gastric Fundus / Q000473:pathology; D005756:Gastritis / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia; D008297:Male; D008875:Middle Aged; D011127:Polyps / Q000473:pathology*; D011706:Pyloric Antrum / Q000473:pathology; D013270:Stomach / Q000473:pathology; D013272:Stomach Diseases / Q000473:pathology*; D014973:Xanthomatosis / Q000473:pathology*