title: Mondor's disease: what's new since 1939?
abstract: Mondor's disease (MD) is a rare and self-limited benign disease first described in 1939. Originally its clinical presentation was a superficial vein thrombosis (SVT) without contiguous skin inflammation of the chest wall veins. Over time its definition has evolved and now also includes subcutaneous thrombosis of the dorsal vein of the penis but also retractile scarring of the fascia after breast surgery without concomitant SVT. In all cases clinical examination constitutes the first step of diagnostic management. It is followed by an ultrasound exploration (US) to search for a thrombus. In about half of all cases the disease is considered as idiopathic and cancer is rare. Whatever the location considered, the follow-up is usually uneventful with low rates of recurrence and of subsequent cancer. Treatment is debated and ranges from therapeutic abstention to anticoagulants or even surgery. It is likely that the new locations and mechanisms (without thrombosis) of the MD have lead to the constitution of a heterogeneous entity precluding from a consensual mode of care.
authors.affiliation: Vascular Medicine Unit, Department of Internal Medicine, Montpellier University Hospital, Montpellier, Cedex 5, France. jp-laroche@chu-montpellier.fr
authors.forename: J P
authors.initials: JP
authors.lastname: Laroche
authors.forename: J
authors.initials: J
authors.lastname: Galanaud
authors.forename: D
authors.initials: D
authors.lastname: Labau
authors.forename: A Khau
authors.initials: AK
authors.lastname: Van Kien
authors.forename: D
authors.initials: D
authors.lastname: Brisot
authors.forename: G
authors.initials: G
authors.lastname: Boge
authors.forename: I
authors.initials: I
authors.lastname: Quéré
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D001941:Breast Diseases / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000266:history / Q000628:therapy; D005260:Female; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008297:Male; D008327:Mammography; D010409:Penile Diseases / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000266:history / Q000628:therapy; D011237:Predictive Value of Tests; D012008:Recurrence; D012307:Risk Factors; D013896:Thoracic Diseases / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000266:history / Q000628:therapy; D017131:Thrombectomy; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color; D018617:Ultrasonography, Doppler, Pulsed; D020246:Venous Thrombosis / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000266:history / Q000628:therapy
chemical_list: D000925:Anticoagulants