title: Associating changes in the immune system with clinical diseases for interpretation in risk assessment.
abstract: This overview unit discusses the relationship between immunosuppression, a potential consequence of immunotoxicity, and disease progression. It also discusses other factors, such as stress and age, that affect disease susceptibility. These factors play an important role in risk assessment for exposures to environmental factors.
authors.affiliation: National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV, USA.
authors.forename: Michael I
authors.initials: MI
authors.lastname: Luster
authors.forename: Dori R
authors.initials: DR
authors.lastname: Germolec
authors.forename: Christine G
authors.initials: CG
authors.lastname: Parks
authors.forename: Laura
authors.initials: L
authors.lastname: Blaciforti
authors.forename: Michael
authors.initials: M
authors.lastname: Kashon
authors.forename: Robert
authors.initials: R
authors.lastname: Luebke
mesh_terms: D006801:Humans; D007107:Immune System / Q000503:physiopathology*; D018570:Risk Assessment