title: Malignant osseous tumors of the pediatric spine.
abstract: In the pediatric population, malignant osseous tumors of the spine include osteosarcoma, Ewing sarcoma, lymphoma, and metastatic neuroblastoma. Although these tumors are rare, prompt diagnosis and recognition are critical to the overall prognosis. Improved understanding of the natural history of spine deformity, combined with advances in imaging, surgical technology, radiation therapy, and chemotherapeutic regimens, has improved survival rates and decreased rates of local recurrence-especially recurrence of low-grade lesions. Prognosis for patients with high-grade lesions with distant metastasis on presentation remains exceedingly poor. Recognition of these spine tumors and prompt referral to a tertiary care center that specializes in oncology can optimize patient outcomes.
authors.affiliation: Department of Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, USA.
authors.forename: Han Jo
authors.initials: HJ
authors.lastname: Kim
authors.forename: Alexander S
authors.initials: AS
authors.lastname: McLawhorn
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Goldstein
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Boland
mesh_terms: D001706:Biopsy; D002648:Child; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D012516:Osteosarcoma / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D011379:Prognosis; D012512:Sarcoma, Ewing / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*