Is body size associated with ovarian cancer in southern Chinese women?
OBJECTIVE
To investigate the association between risk of ovarian cancer and body size among southern Chinese women.


METHODS
A hospital-based case-control study was undertaken in Guangzhou, Guangdong Province, from 2006 to 2008. Participants were 500 incident ovarian cancer patients and 500 controls, with a mean age of 59 years. Information on adult height and weight was obtained via face-to-face interview using a structured questionnaire. Logistic regression analyses were performed to assess the association between anthropometric factors and the ovarian cancer risk.


RESULTS
Compared with women having body weight ≤50 kg and body mass index (BMI) <18.5 kg/m(2), the adjusted odds ratios (ORs) of ovarian cancer were 1.84 (95 % confidence interval (CI) 1.34-2.54) and 1.77 (95 % CI 1.04-3.02) in those women who had body weight >55 kg and BMI ≥23 kg/m(2), respectively. Significant dose-response relationships were also observed for both weight and BMI (p < 0.01). Body height was not significantly associated with ovarian cancer risk.


CONCLUSIONS
Body weight and BMI were associated with increased risk of ovarian cancer in southern Chinese women.
School of Public Health, Curtin University, GPO Box U 1987, Perth, WA, 6845, Australia.
Dada
D
Su
Maria
M
Pasalich
Colin W
CW
Binns
Andy H
AH
Lee
D015992:Body Mass Index; D001835:Body Weight; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000453:epidemiology*; D012307:Risk Factors