Dissociation of aryl sulfonyl phthalimide radical anions: relevance to the biological activity of aryl sulfonyl amides.
The reduction of two aryl sulfonyl phthalimides leads to the corresponding radical anions. Surprisingly, that of the nitro-derivative decomposes faster than that of the methyl derivative. A theoretical investigation along with application of the dissociative ET theory to the decomposition of radical anions allows rationalization of this unexpected behavior.
University of Guelph, Guelph, Ontario N1G 2W1, Canada. ahoumam@uoguelph.ca
Abdelaziz
A
Houmam
Emad M
EM
Hamed
D000577:Amides / Q000737:chemistry*; D000838:Anions / Q000737:chemistry; D055664:Electrochemical Techniques; D004566:Electrodes; D004579:Electron Transport; D005609:Free Radicals / Q000737:chemistry*; D010797:Phthalimides / Q000737:chemistry*; D011789:Quantum Theory; D013441:Sulfinic Acids / Q000737:chemistry*; D013816:Thermodynamics
D000577:Amides; D000838:Anions; D005609:Free Radicals; D010797:Phthalimides; D013441:Sulfinic Acids; C037431:phthalimide