An ecological study on childhood autism.
METHODS
Idiopathic autism, suspected to be caused by exposure of genetically susceptible individuals to unknown environmental triggers, has increased dramatically in the past 25 years. The objectives of our study were to determine, using a linear regression model, whether the county prevalence of autism in the Pacific Northwest of the United States was associated with the source of drinking water for that county and whether this relationship was dependent on the level of environmental pollutants and meteorological factors in the county.


RESULTS
We found the previously reported relationship between precipitation and autism in a county was dependent on the amount of drinking water derived from surface sources in the county. We also found a positive association between the EPA's risk of neurological disease and autism, but this relationship was only present in warm areas.


CONCLUSIONS
Our study provides evidence for the hypothesis that environmental factors are associated with autism and that meteorological factors play a role in this relationship.
Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, 550 University Avenue, Charlottetown, PE C1A 4P3, Canada. ssthilaire@upei.ca
Sophie
S
St-Hilaire
Victor O
VO
Ezike
Henrik
H
Stryhn
Michael A
MA
Thomas
D000293:Adolescent; D001321:Autistic Disorder / Q000453:epidemiology / Q000209:etiology*; D002140:California / Q000453:epidemiology; D002648:Child; D016208:Databases, Factual; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008685:Meteorological Concepts; D009922:Oregon / Q000453:epidemiology; D014861:Washington / Q000453:epidemiology