Bronchitis caused by Bordetella holmesii in a child with asthma misdiagnosed as mycoplasmal infection.
We report a case of a bronchitis caused by Bordetella holmesii in a 2-year-old girl with asthma. The patient had a moderate fever and productive cough, and her condition was initially diagnosed as mycoplasmal bronchitis on the basis of her clinical symptoms and rapid serodiagnosis of mycoplasmal infection. She was treated with a bronchodilator and clarithromycin, which resulted in complete recovery. However, after the initial diagnosis, nucleic acid amplification tests of her sputum showed the absence of both Mycoplasma pneumoniae and Bordetella pertussis infections. Sputum culture showed the presence of a slow-growing, gram-negative bacillus in pure culture on Bordetella agar plates; the bacillus was later identified as B. holmesii. B. holmesii infection is rare in immunocompetent children; however, the organism is a true pathogen that can cause bronchitis in young children with asthma.
Department of Infectious Diseases, Osaka Prefectural Institute of Public Health, Osaka, Japan.
Chihiro
C
Katsukawa
Chieko
C
Kushibiki
Atsumi
A
Nishito
Rikou
R
Nishida
Norimitsu
N
Kuwabara
Ryuji
R
Kawahara
Nao
N
Otsuka
Yusuke
Y
Miyaji
Hiromi
H
Toyoizumi-Ajisaka
Kazunari
K
Kamachi
D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis* / Q000382:microbiology; D001884:Bordetella / Q000187:drug effects / Q000302:isolation & purification*; D001885:Bordetella Infections / Q000175:diagnosis* / Q000382:microbiology; D001991:Bronchitis / Q000175:diagnosis* / Q000382:microbiology; D002675:Child, Preschool; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D009175:Mycoplasma Infections / Q000175:diagnosis / Q000382:microbiology; D013183:Sputum / Q000382:microbiology
D000900:Anti-Bacterial Agents