Neonatal intermittent hypoxia induces persistent alteration of baroreflex in adult male rats.
Baroreflex is involved in the regulation of arterial blood pressure (BP). An increase in BP activates vagal inhibitory pathways to decrease heart rate; a concomitant decrease in sympathetic discharge reduces vascular resistance. Both responses reduce BP towards normal value. Conversely, a decrease in BP produces opposite effects to increase heart rate and vascular resistance.
Department of Pediatrics, Laval University, Québec, Canada. Cecile.Dolbec@crchuq.ulaval.ca
Cécile A
CA
Julien
Richard
R
Kinkead
Vincent
V
Joseph
Aida
A
Bairam
D000818:Animals; D000831:Animals, Newborn; D017704:Baroreflex / Q000502:physiology*; D001794:Blood Pressure; D006339:Heart Rate; D000860:Hypoxia / Q000503:physiopathology*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley