The first case of fatal pneumonia caused by Panton-Valentine leukocidin-producing Staphylococcus aureus in an infant in the Czech Republic.
Panton-Valentine leukocidin-producing strains of Staphylococcus aureus can cause severe skin and soft tissue infections and necrotizing pneumonia with a high mortality rate. This is a report on the first case of fatal pneumonia with mediastinitis in an infant in the Czech Republic. The causative agent was a methicillin-susceptible S. aureus strain with pronounced production of the PVL toxin and hyperproduction of enterotoxin A.
1st Department of Infectious Diseases, Bulovka Hospital, 2nd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
Helena
H
Ambrozova
Vilma
V
Maresova
Martin
M
Fajt
Petr
P
Pavlicek
Hana
H
Rohacova
Ivana
I
Machova
Petr
P
Petras
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001427:Bacterial Toxins; D018153:Czech Republic; D004338:Drug Combinations; D004768:Enterotoxins; D005098:Exotoxins; D017809:Fatal Outcome; D005838:Genotype; D006801:Humans; D007223:Infant; D007956:Leukocidins; D008297:Male; D010641:Phenotype; D011023:Pneumonia, Staphylococcal / Q000382:microbiology / Q000473:pathology*; D013211:Staphylococcus aureus / Q000145:classification
D000900:Anti-Bacterial Agents; D001427:Bacterial Toxins; D004338:Drug Combinations; D004768:Enterotoxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin; C026066:enterotoxin A, Staphylococcal