Removal of acidic or basic α-amino acids in water by poorly water soluble scandium complexes.
To recognize α-amino acids with highly polar side chains in water, poorly water soluble scandium complexes with both Lewis acidic and basic portions were synthesized as artificial receptors. A suspension of some of these receptor molecules in an α-amino acid solution could remove acidic and basic α-amino acids from the solution. The compound most efficient at preferentially removing basic α-amino acids (arginine, histidine, and lysine) was the receptor with 7,7'-[1,3-phenylenebis(carbonylimino)]bis(2-naphthalenesulfonate) as the ligand. The neutral α-amino acids were barely removed by these receptors. Removal experiments using a mixed amino acid solution generally gave results similar to those obtained using solutions containing a single amino acid. The results demonstrated that the scandium complex receptors were useful for binding acidic and basic α-amino acids.
National Food Research Institute, National Agriculture and Food Research Organization (NARO), 2-1-12 Kannondai, Tsukuba, Ibaraki 305-8642, Japan. hayn@affrc.go.jp
Nobuyuki
N
Hayashi
Shigeki
S
Jin
Tomomi
T
Ujihara
D000596:Amino Acids / Q000737:chemistry*; D024361:Amino Acids, Basic / Q000737:chemistry*; D058116:Lewis Acids / Q000737:chemistry*; D058115:Lewis Bases / Q000737:chemistry*; D008024:Ligands; D009942:Organometallic Compounds / Q000737:chemistry*; D012538:Scandium / Q000737:chemistry*; D012996:Solutions / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
D000596:Amino Acids; D024361:Amino Acids, Basic; D058116:Lewis Acids; D058115:Lewis Bases; D008024:Ligands; D009942:Organometallic Compounds; D012996:Solutions; D014867:Water; D012538:Scandium