Comparative material study and synthesis of 4-(4-nitrophenyl)oxazol-2-amine via sonochemical and thermal method.
The present paper deals with the synthesis of aminooxazole derivatives via thermal and ultrasonic methods using deep eutectic solvent as medium. It was observed that ultrasound-assisted method gave 90% yield in just 8min as against 3.5h required to get 69% yield by thermal method. One of the compounds 4-(4-nitrophenyl)-1,3-oxazol-2-amine synthesized by both methods were subjected to material characterization study via XRD, TGA and SEM analysis. It was observed that use of ultrasound not only increased the rate of reaction but also improved the quality of product obtained. The crystallinity of the product from ultrasound method was 21.12% whereas thermal method fetched only 8.33% crystallinity thereby improving crystallinity by almost 60%. In addition, sonochemical synthesis also saved more than 70% energy as depicted by energy calculations.
Dyestuff Technology Department, Institute of Chemical Technology, Matunga, Mumbai 400 019, India.
Balvant S
BS
Singh
Hyacintha R
HR
Lobo
Dipak V
DV
Pinjari
Krishna J
KJ
Jarag
Aniruddha B
AB
Pandit
Ganapati S
GS
Shankarling