Congenital solitary infantile myofibromatosis involving the spinal cord.
Infantile myofibromatosis, a rare mesenchymal disorder that develops in early childhood, is classified by the number of lesions that occur: solitary or multicentric. Involvement of the CNS is unusual in either type. Infantile myofibromatosis in the spine is exceptional, and most published cases represent a secondary invasion. Here, the authors report on an 8-month-old girl presenting with weakness below the ankle and an intraspinal mass extending from T-6 to the conus. The patient underwent only partial surgical removal of the lesion, and the pathology was confirmed as infantile myofibromatosis. After the operation, weakness in the lower extremities gradually improved; however, she could not walk at the time of the final follow-up. On follow-up MRI performed 19 months after the operation, the residual lesion remained unchanged with decreased enhancement.
Divisions of Pediatric Neurosurgery, Seoul National University Children’s Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Eun Ji
EJ
Kim
Kyu-Chang
KC
Wang
Ji Yeoun
JY
Lee
Ji Hoon
JH
Phi
Sung-Hye
SH
Park
Jung-Eun
JE
Cheon
Young Eun
YE
Jang
Seung-Ki
SK
Kim
D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D007796:Laminectomy; D008279:Magnetic Resonance Imaging; D008854:Microscopy, Electron; D018224:Myofibromatosis / Q000151:congenital* / Q000473:pathology / Q000601:surgery*; D009363:Neoplasm Proteins / Q000378:metabolism; D009419:Nerve Tissue Proteins / Q000378:metabolism; D011182:Postoperative Care; D013120:Spinal Cord Neoplasms / Q000151:congenital* / Q000473:pathology / Q000601:surgery*
D009363:Neoplasm Proteins; D009419:Nerve Tissue Proteins