Dual-energy perfusion CT of non-diseased lung segments using dual-source CT: correlation with perfusion SPECT.
OBJECTIVE
To determine the utility of dual-energy perfusion CT (DEpCT) of non-diseased lung segments, using dual-source CT, in comparison with perfusion single-photon emission computed tomography (SPECT).


METHODS
28 patients (18 male and 10 female; mean age 63 years; age range 18-86 years) underwent DEpCT and SPECT within a 3-day interval. The presence and location of perfusion defects in each segment of the lungs were evaluated.


RESULTS
Perfusion defects were noted in 7 of 361 segments (1.9%) by DEpCT and in 19 of 361 segments (5.3%) by perfusion SPECT. DEpCT was in good agreement with perfusion SPECT for 338 of 361 segments (93.6%). Intraobserver agreement was also good, ranging from 93.4 to 93.6% (κ = 0.64-0.75, p < 0.01).


CONCLUSIONS
For non-diseased lung segments, DEpCT correlated well with SPECT.
Department of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi 755-8505, Japan. kyoshie@yamaguchi-u.ac.jp
Yoshie
Y
Kunihiro
Munemasa
M
Okada
Naofumi
N
Matsunaga
Yuichi
Y
Sano
Shohei
S
Kudomi
Kazuyoshi
K
Suga
Shoji
S
Kido
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D005260:Female; D006801:Humans; D007479:Iopamidol; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011856:Radiographic Image Enhancement / Q000379:methods; D015203:Reproducibility of Results; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D055815:Young Adult
D003287:Contrast Media; D007479:Iopamidol