[Pulmonary toxoplasmosis in immunosuppressed patient].
Pulmonary toxoplasmosis occurs mainly in immunosuppressed patients and its diagnosis mainly relies upon biological confirmation of the parasite. We present the case of a 47 years patient in medullar aplasia after induction chemotherapy for acute lymphoblastic leukemia that developed pulmonary infiltrates of parasitic origin. The diagnosis of pulmonary toxoplasmosis was established after identification of the parasite in brochioloalveolar lavage fluid (BAL) and peripheral blood. Serological tests are of limited utility in immunosuppressed patients. We used classical methods for the diagnosis of parasitosis but they are being replaced by molecular methods. Polymerase Chain Reaction (PCR) allows a highly specific and sensitive diagnosis on any sample but it cannot be performed in any center.
Universităţii de Medicină si Farmacie "Grigore T. Popa" - Iaşi.
Carmen
C
Rîpă
Ingrid
I
Cojocaru
Mariana
M
Luca
Cătălina Mihaela
CM
Luca
Maria
M
Leon
Roxana-Gabriela
RG
Bahnea
D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects; D001992:Bronchoalveolar Lavage Fluid / Q000469:parasitology*; D004797:Enzyme-Linked Immunosorbent Assay; D017809:Fatal Outcome; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014122:Toxoplasma / Q000276:immunology / Q000469:parasitology; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000276:immunology / Q000469:parasitology / Q000628:therapy
D000970:Antineoplastic Agents