Metachronous penile metastasis from rectal cancer after total pelvic exenteration.
Despite its abundant vascularization and extensive circulatory communication with neighboring organs, metastases to the penis are a rare event. A 57-year-old male, who had undergone total pelvic exenteration for rectal cancer sixteen months earlier, demonstrated an abnormal uptake within his penis by positron emission tomography/computed tomography. A single elastic nodule of the middle penis shaft was noted deep within Bucks fascia. No other obvious recurrent site was noted except the penile lesion. Total penectomy was performed as a curative resection based on a diagnosis of isolated penile metastasis from rectal cancer. A histopathological examination revealed an increase of well differentiated adenocarcinoma in the corpus spongiosum consistent with his primary rectal tumor. The immunohistochemistry of the tumor cells demonstrated positive staining for cytokeratin 20 and negative staining for cytokeratin 7, which strongly supported a diagnosis of penile metastasis from the rectum. The patient is alive more than two years without any recurrence.
Department of Surgery, Tokyo Metropolitan Bokutoh Hospital, 4-23-15 Koto-bashi, Sumida-ku, Tokyo 1308575, Japan.
Yuta
Y
Kimura
Dai
D
Shida
Keiichi
K
Nasu
Hiroki
H
Matsunaga
Masahiro
M
Warabi
Satoru
S
Inoue
D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010385:Pelvic Exenteration; D010412:Penile Neoplasms / Q000175:diagnosis / Q000556:secondary*; D012004:Rectal Neoplasms / Q000473:pathology* / Q000601:surgery