Ewing-like adamantinoma.
The Ewing-like variation of adamantinoma is a rare entity, leading to challenge its differential diagnosis, notably with Ewing's sarcoma. We are reporting a case of a 20-year-old male who presented with swelling in the left leg that had progressed over a 2-year period. X-rays revealed a tumour in the tibia that was intracortical, osteolytic, multilocular and invaded the soft tissues. A surgical biopsy was performed. Histopathology examination showed a tumour growth with small round cells expressing CD99. A diagnosis of Ewing's sarcoma was made. Since the patient declined surgical treatment, chemotherapy was administered. Two years later, the patient returned because the tumour had grown in size. A second biopsy was performed. Microscopic evaluation showed a tumour growth with osteofibrous and epithelial components, which expressed pankeratin and vimentin, but was negative for CD99. A diagnosis of Ewing-like adamantinoma was made.
Histopathology Department, Salah Azaiez Institute, Bab Saâdoun, 1006 Tunis, Tunisia. hamdanemoncef@yahoo.fr
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Hamdane
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Charfi
M
M
Driss
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H
Nouri
R
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Sellami-Dhouib
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Mrad
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Mestiri
K
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Ben Romdhane
D050398:Adamantinoma / Q000175:diagnosis* / Q000628:therapy; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D012512:Sarcoma, Ewing / Q000175:diagnosis*; D013977:Tibia; D055815:Young Adult