No association between polymorphisms and haplotypes of the AVPR1b, CRHR1 and NR3C1 genes and depression with melancholic features in the course of bipolar disorder.
The present study included 130 patients with melancholic depression in the course of bipolar disorder and 732 healthy controls. No association was found for alleles, genotypes, or haplotype analysis for NR3C1, AVPR1b, and CRHR1 genes and melancholic depression.
Department of Adult Psychiatry, Poznan University of Medical Sciences, ul. Szpitalna 27/33; 60-572 Poznan, Poland. alrodziewicz@ump.edu.pl
Anna
A
Leszczyńska-Rodziewicz
Aleksandra
A
Szczepankiewicz
Monika
M
Dmitrzak-Węglarz
Aleksandra
A
Rajewska-Rager
Maria
M
Skibińska
Joanna
J
Hauser
D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D007223:Infant; D008875:Middle Aged; D011110:Polymorphism, Genetic / Q000235:genetics*; D018019:Receptors, Corticotropin-Releasing Hormone / Q000235:genetics*; D011965:Receptors, Glucocorticoid / Q000235:genetics*; D017483:Receptors, Vasopressin / Q000235:genetics*; D055815:Young Adult; D000099052:CRF Receptor, Type 1
C497713:NR3C1 protein, human; D018019:Receptors, Corticotropin-Releasing Hormone; D011965:Receptors, Glucocorticoid; D017483:Receptors, Vasopressin; D000099052:CRF Receptor, Type 1