[Use of drug-eluting balloons for coronary interventions: current indications and perspectives].
The paclitaxel-eluting balloon is an emerging percutaneous coronary angioplasty tool which aim is to prevent restenosis by delivering a high intravessel paclitaxel dose during balloon inflation. It has been already approved in the treatment of bare metal stent restenosis and is being investigated in drug-eluting stent restenosis. For the treatment of de novo lesions, it could be used alone or in combination with bare metal stent implantation. Most interesting results were obtained by a drug-eluting balloon alone strategy in small vessels angioplasty. Current and upcoming results of this evolving technology are reviewed.
Unité d'hémodynamique diagnostique et interventionnelle, Institut Lorrain du coeur et des vaisseaux Louis-Mathieu, hôpitaux de Brabois, CHU de Nancy, allée du Morvan, 54511 Vandoeuvre-lès-Nancy, France. m.angioi@chu-nancy.fr
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D015906:Angioplasty, Balloon, Coronary / Q000592:standards / Q000639:trends; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000473:pathology / Q000517:prevention & control / Q000628:therapy*; D023903:Coronary Restenosis / Q000628:therapy; D054855:Drug-Eluting Stents / Q000592:standards / Q000639:trends; D006801:Humans; D017239:Paclitaxel / Q000008:administration & dosage*; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*; D016896:Treatment Outcome
D010975:Platelet Aggregation Inhibitors; D017239:Paclitaxel