Ruthenium(II) complexes containing quinone based ligands: synthesis, characterization, catalytic applications and DNA interaction.
1,2-Naphthaquinone reacts with amines such as semicarbazide, isonicotinylhydrazide and thiosemicarbazide in high yield procedure with the formation of tridentate ligands HL(n) (n=1-3). By reaction of ruthenium(II) starting complexes and quinone based ligands HL(n) (n=1-3), a series of ruthenium complexes were synthesized and characterized by elemental and spectroscopic methods (FT-IR, electronic, (1)H, (13)C, (31)P NMR and ESI-MS). The ligands were coordinated to ruthenium through quinone oxygen, imine nitrogen and enolate oxygen/thiolato sulfur. On the basis of spectral studies an octahedral geometry may be assigned for all the complexes. Further, the catalytic oxidation of primary, secondary alcohol and transfer hydrogenation of ketone was carried out. The DNA cleavage efficiency of new complexes has also been tested.
Department of Chemistry, Periyar University, Salem 636 011, India.
P
P
Anitha
R
R
Manikandan
A
A
Endo
T
T
Hashimoto
P
P
Viswanathamurthi
D000438:Alcohols / Q000737:chemistry; D002384:Catalysis; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D004247:DNA / Q000737:chemistry; D053837:DNA Cleavage / Q000187:drug effects*; D006865:Hydrogenation; D007659:Ketones / Q000737:chemistry; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D010084:Oxidation-Reduction; D011809:Quinones / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D012428:Ruthenium / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization; D017550:Spectroscopy, Fourier Transform Infrared
D000438:Alcohols; D056831:Coordination Complexes; D007659:Ketones; D008024:Ligands; D011809:Quinones; D012428:Ruthenium; D004247:DNA