Variation in outcomes across centers after surgery for lumbar stenosis and degenerative spondylolisthesis in the spine patient outcomes research trial.
METHODS
Retrospective review of a prospectively collected database.


OBJECTIVE
To examine whether short- and long-term outcomes after surgery for lumbar stenosis (SPS) and degenerative spondylolisthesis (DS) vary across centers.


BACKGROUND
Surgery has been shown to be of benefit for both SPS and DS. For both conditions, surgery often consists of laminectomy with or without fusion. Potential differences in outcomes of these overlapping procedures across various surgical centers have not yet been investigated.


METHODS
Spine Patient Outcomes Research Trial cohort participants with a confirmed diagnosis of SPS or DS undergoing surgery were followed from baseline at 6 weeks, 3, 6, and 12 months, and yearly thereafter, at 13 spine clinics in 11 US states. Baseline characteristics and short- and long-term outcomes were analyzed.


RESULTS
A total of 793 patients underwent surgery. Significant differences were found between centers with regard to patient race, body mass index, treatment preference, neurological deficit, stenosis location, severity, and number of stenotic levels. Significant differences were also found in operative duration and blood loss, the incidence of durotomy, the length of hospital stay, and wound infection. When baseline differences were adjusted for, significant differences were still seen between centers in changes in patient functional outcome (Short Form-36 bodily pain and physical function, and Oswestry Disability Index) at 1 year after surgery. In addition, the cumulative adjusted change in the Oswestry Disability Index Score at 4 years significantly differed among centers, with Short Form-36 scores trending toward significance.


CONCLUSIONS
There is a broad and statistically significant variation in short- and long-term outcomes after surgery for SPS and DS across various academic centers, when statistically significant baseline differences are adjusted for. The findings suggest that the choice of center affects outcome after these procedures, although further studies are required to investigate which center characteristics are most important.
Section of Neurosurgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA. atman.desai@hitchcock.org
Atman
A
Desai
Kimon
K
Bekelis
Perry A
PA
Ball
Jon
J
Lurie
Sohail K
SK
Mirza
Tor D
TD
Tosteson
Wenyan
W
Zhao
James N
JN
Weinstein
D000368:Aged; D002986:Clinical Trials as Topic; D004185:Disability Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008159:Lumbar Vertebrae / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care / Q000379:methods / Q000706:statistics & numerical data; D012189:Retrospective Studies; D013130:Spinal Stenosis / Q000601:surgery*; D013131:Spine / Q000473:pathology / Q000601:surgery*; D013168:Spondylolisthesis / Q000601:surgery*; D013514:Surgical Procedures, Operative / Q000379:methods; D011795:Surveys and Questionnaires; D013997:Time Factors