[Serum triacylglycerol-lowering effect of soybean beta-conglycinin in hyperlipidemic women].
OBJECTIVE
Improving effects on serum triacylglyceride in women with hypertriacylglycerolemia by soybean beta-conglycinin.


METHODS
A placebo-controlled, randomized, double-blind study was conducted in 100 women aged 40-60 with TC > 6.22 mmol/L (or TG > 1.70 mmol/L). The subjects were administered beta-conglycinin 4.6g (high dose) in 8 test tablets and 2.3g(low dose) in 4 test tablets daily for the two test groups and 4 placebo tablets containing no beta-conglycinin for the control group for 12 weeks.


RESULTS
Compared to the control group, serum triacylglycerol in the high dose group was significantly reduced at the 6th week (P < 0.001) and the 12th week (P = 0.001) of the trial. Serum triacylglycerol in the low dose group was reduced at the 6th week (P < 0.001) of the trial.


CONCLUSIONS
Soybean beta-conglycinin seemed to have a positive effect of reducing serum triglycerides and improving serum lipids in people with hyperlipidemia.
School of Public Health, Peking University, Beijing 100191, China. suvivisu@live.cn
Meng
M
Jia
Xinggang
X
Zhuo
Fangqun
F
Han
Defu
D
Ma
Yumei
Y
Zhang
Ziyi
Z
Li
Peiyu
P
Wang
D000328:Adult; D052179:Antigens, Plant / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005916:Globulins / Q000627:therapeutic use*; D006801:Humans; D006949:Hyperlipidemias / Q000188:drug therapy*; D008875:Middle Aged; D055314:Seed Storage Proteins / Q000627:therapeutic use*; D030262:Soybean Proteins / Q000627:therapeutic use*; D014280:Triglycerides
D052179:Antigens, Plant; D005916:Globulins; D055314:Seed Storage Proteins; D030262:Soybean Proteins; D014280:Triglycerides; C013894:beta-conglycinin protein, Glycine max