ZFIN, the Zebrafish Model Organism Database: increased support for mutants and transgenics.
ZFIN, the Zebrafish Model Organism Database (http://zfin.org), is the central resource for zebrafish genetic, genomic, phenotypic and developmental data. ZFIN curators manually curate and integrate comprehensive data involving zebrafish genes, mutants, transgenics, phenotypes, genotypes, gene expressions, morpholinos, antibodies, anatomical structures and publications. Integrated views of these data, as well as data gathered through collaborations and data exchanges, are provided through a wide selection of web-based search forms. Among the vertebrate model organisms, zebrafish are uniquely well suited for rapid and targeted generation of mutant lines. The recent rapid production of mutants and transgenic zebrafish is making management of data associated with these resources particularly important to the research community. Here, we describe recent enhancements to ZFIN aimed at improving our support for mutant and transgenic lines, including (i) enhanced mutant/transgenic search functionality; (ii) more expressive phenotype curation methods; (iii) new downloads files and archival data access; (iv) incorporation of new data loads from laboratories undertaking large-scale generation of mutant or transgenic lines and (v) new GBrowse tracks for transgenic insertions, genes with antibodies and morpholinos.
ZFIN, 5291 University of Oregon, Eugene, OR 97403-5291, USA. dhowe@zfin.org
Douglas G
DG
Howe
Yvonne M
YM
Bradford
Tom
T
Conlin
Anne E
AE
Eagle
David
D
Fashena
Ken
K
Frazer
Jonathan
J
Knight
Prita
P
Mani
Ryan
R
Martin
Sierra A Taylor
SA
Moxon
Holly
H
Paddock
Christian
C
Pich
Sridhar
S
Ramachandran
Barbara J
BJ
Ruef
Leyla
L
Ruzicka
Kevin
K
Schaper
Xiang
X
Shao
Amy
A
Singer
Brock
B
Sprunger
Ceri E
CE
Van Slyke
Monte
M
Westerfield
D000818:Animals; D030801:Animals, Genetically Modified; D030541:Databases, Genetic; D023281:Genomics; D020407:Internet; D023421:Models, Animal; D009154:Mutation; D010641:Phenotype; D015027:Zebrafish / Q000235:genetics*