Cytisin amidophosphate--the new cytoprotector.
This article describes the results of a clinical study of O,O dimethyl-N-cytinizylphosphate in healthy volunteers and 142 patients with the verified diagnosis of acute toxic hepatitis. The tolerability was good. The efficiency of the drug is considered to be very high, normalization of the state took less time in comparison with standard treatment; a significant improvement was achieved immediately after the first injection.
Center for Life Sciences, Nazarbayev University, Kabanbay batyr ave. 53, Astana, Republic of Kazakhstan.
Zhaxybay
Z
Zhumadilov
Talgat
T
Nurgozhin
Alexandr
A
Gulyaev
Sabira
S
Zhaugasheva
Arystan
A
Gazaliyev
Bakytgul
B
Ermekbayeva
Gulnara
G
Abuova
Almas
A
Kenessary
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000470:Alkaloids / Q000008:administration & dosage* / Q000737:chemistry; D000975:Antioxidants / Q000008:administration & dosage* / Q000737:chemistry; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy*; D019610:Cytoprotection / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009943:Organophosphorus Compounds / Q000008:administration & dosage* / Q000737:chemistry; D018384:Oxidative Stress / Q000187:drug effects; D016896:Treatment Outcome; D055815:Young Adult
D000470:Alkaloids; D000975:Antioxidants; C576295:O,O dimethyl-N-cytinizylphosphate; D009943:Organophosphorus Compounds