Dual-imaging enabled cancer-targeting nanoparticles.
The development of dual-imaging enabled cancer-targeting nanoparticles (DICT-NPs) is reported based on newly developed biodegradable photoluminescent polymers and superparamagnetic iron oxide nanoparticles. DICT-NPs possess capabilities of dual-imaging (magnetic resonance imaging and optical imaging), magnetic targeting, and potentially selective targeting for cancer cells. The development of DICT-NPs address the concerns in dual-imaging nanoparticles where photobleaching organic dyes and cytotoxic quantum dots are usually adopted.
Department of Bioengineering, The University of Texas at Arlington, 500 UTA Boulevard, Arlington, TX 76019, USA.
Aniket S
AS
Wadajkar
Tejaswi
T
Kadapure
Yi
Y
Zhang
Weina
W
Cui
Kytai T
KT
Nguyen
Jian
J
Yang
D045744:Cell Line, Tumor; D003287:Contrast Media / Q000737:chemistry; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008856:Microscopy, Fluorescence / Q000379:methods*; D053758:Nanoparticles; D011471:Prostatic Neoplasms / Q000473:pathology*; D013382:Subtraction Technique
D003287:Contrast Media