Metabolic engineering of microorganisms for vitamin C production.
Vitamin C, an important organic acid, is widely used in the industries of pharmaceuticals, cosmetics, food, beverage and feed additives. Compared with the Reichstein method, biotechnological production of vitamin C is an attractive approach due to the low cost and high product quality. In this chapter, biosynthesis of vitamin C, including one-step fermentation processes and two-step fermentation processes are discussed and compared. Furthermore, the prospects of the biotechnological production of vitamin C are also presented.
School of Biotechnology, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China.
Jingwen
J
Zhou
Guocheng
G
Du
Jian
J
Chen
D001205:Ascorbic Acid / Q000096:biosynthesis*; D001410:Bacillus megaterium / Q000235:genetics / Q000378:metabolism; D005285:Fermentation; D005947:Glucose / Q000378:metabolism; D006801:Humans; D060847:Metabolic Engineering / Q000379:methods*; D056265:Microbial Interactions; D008827:Microbiological Phenomena / Q000235:genetics; D013696:Temperature
D005947:Glucose; D001205:Ascorbic Acid