Red cell distribution width and mean platelet volume in amyloidosis.
We aimed to determine whether red cell distribution width (RDW) and mean platelet volume (MPV) values differ between patients with reactive amyloid A (AA) amyloidosis due to chronic inflammatory disease and in healthy participants. In this study, 33 patients with AA amyloidosis and 40 age- and sex-matched healthy controls were enrolled. Erythrocyte sedimentation rate (ESR), RDW, platelet count (PLT), and MPV levels were retrospectively obtained from our computerized patient database. We found RDW, ESR, and PLT levels to be significantly higher in patients with AA amyloidosis compared with the controls (P < .0001). Mean platelet volume was significantly lower in patients with amyloidosis (P < .0001). Inflammatory diseases such as AA amyloidosis may demonstrate low MPV and high RDW levels.
1Department of Nephrology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
Emre
E
Erdem
Dilek
D
Erdem
Melda
M
Dilek
Coşkun
C
Kaya
Ahmet
A
Karataş
Engin
E
Kut
Murat
M
Çoban
Kuddusi
K
Cengiz
Nurol
N
Arιk
Tekin
T
Akpolat
D000328:Adult; D000686:Amyloidosis / Q000097:blood*; D004909:Erythrocyte Indices; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume / Q000379:methods