Clinical and surgical evaluation of the indication of postoperative antibiotic prescription in third molar surgery.
OBJECTIVE
The aim of this study was to evaluate the need for antibiotic prescription in third molar surgery.


METHODS
A double-blind randomized study was carried out with 71 patients from CODONT (Dentistry Center of the Police of São Paulo). Amoxicillin, clindamycin, or no medication was administered for 7 days immediately after surgery. The participants evaluated the presence of pain, edema, interincisal distance (ID), presence of infection, Pell and Gregory classification, rescue analgesia, osteotomy, and odontosection.


RESULTS
There was no difference (P < .05) between antibiotics and control over the surgery duration, dose, visual analog scale (VAS), ID, and edema, yet significant differences were seen over time for VAS, edema, and ID.


CONCLUSIONS
Antibiotic prescription should not be indicated in all clinical conditions, yet it is necessary to correctly evaluate factors such as systemic condition of the patient, skill of the operator, and contamination of the surgical environment.
Department of Integrated Clinical Medicine, Stomatology, Universidade de São Paulo, São Paulo, Brazil.
Carlos Alberto
CA
Adde
Mário Sérgio
MS
Soares
Marcelo Munhóes
MM
Romano
Talita Girio
TG
Carnaval
Roberta Moura
RM
Sampaio
Fernanda Palone
FP
Aldarvis
Luiz Renato Tobias de Aguiar
LR
Federico
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D001938:Brazil; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008964:Molar, Third / Q000601:surgery*; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*; D014081:Tooth Extraction; D014095:Tooth, Impacted / Q000601:surgery*
D000900:Anti-Bacterial Agents