Topical use of sodium cromoglicate (cromolyn sodium) to treat atopic dermatitis and other skin allergies.
Sodium cromoglicate (cromolyn sodium) is a very well-known medicine that has been used for many years for various allergic conditions. The topical use of this medicine is less known, and there are no commercial medicines of cream, gel, or lotion in most of the world. This article summarizes the clinical data accumulated from seventeen trials that checked the topical efficacy and safety of sodium cromoglicate and analyzes the clinical implementations of this medicine in the topical treatment of atopic dermatitis and other skin allergies. In addition, this article analyzes the various formulations that have been used in the clinical trials in an attempt to find the optimal formulation. The topical use of sodium cromoglicate seemed to have a promising potential, and implementing the data of this article can allow the compounding pharmacist a very interesting professional activity in very common and widespread allergic pathologies.
Super-Pharm, Petach-Tikvah, Israel. eyalz@super-pharm.co.il
Eyal
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Zur
D000287:Administration, Topical; D002626:Chemistry, Pharmaceutical; D002986:Clinical Trials as Topic; D004205:Cromolyn Sodium / Q000008:administration & dosage* / Q000494:pharmacology; D003876:Dermatitis, Atopic / Q000188:drug therapy*; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy*
D004205:Cromolyn Sodium