Is HUB1 a hub for plant fitness?
Recently, we have identified circadian clock genes as targets of Histone Monoubiquitination1 (HUB1) in Arabidopsis from a transcriptome comparison between the hub1-1 mutant and HUB1 overexpression lines. HUB1 affected the amplitudes of the circadian clock gene expression profiles in the hub1-1 mutant that coincided with reduced monoubiquitination of histone H2B at their coding regions. Here we showed that parameters for plant fitness are altered in HUB1 mutant and overexpression lines, suggesting that the histone H2B monoubiquitination status affects plant fitness.
Department of Plant Systems Biology, VIB, Gent, Belgium.
Kristiina
K
Himanen
Tommaso Matteo
TM
Boccardi
Riet
R
De Rycke
Ojola Patrick
OP
Odeny
Mieke
M
Van Lijsebettens
D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism* / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D002736:Chloroplasts / Q000378:metabolism / Q000502:physiology; D018506:Gene Expression Regulation, Plant; D030821:Plants, Genetically Modified / Q000235:genetics / Q000378:metabolism / Q000502:physiology; D044767:Ubiquitin-Protein Ligases / Q000235:genetics / Q000378:metabolism*; D054875:Ubiquitination
D029681:Arabidopsis Proteins; C521255:HUB1 protein, Arabidopsis; D044767:Ubiquitin-Protein Ligases