Short term clinical outcome of children with rotavirus infection at Kenyatta National Hospital, Nairobi.
BACKGROUND
Rotavirus infection is the single most common cause of acute gastroenteritis in children under five years of age. Rotavirus gastroenteritis has a high morbidity and mortality in children in Kenya.


OBJECTIVE
To determine the short term clinical outcome for children admitted to Kenyatta National Hospital with rotavirus gastroenteritis and the correlates of poor outcome.


METHODS
Short longitudinal survey.


METHODS
Kenyatta National Hospital from February to May 2008.


METHODS
Five hundred children were screened using a rapid antigen detection kit and ELISA.


RESULTS
Of the 191 children who tested positive for rotavirus in stool; 172 children were recruited into the study. Eighty eight per cent of the patients were discharged within one week, 8.1% stayed for more than seven days while 4.1% died. Children who had co-morbidities such as malnutrition, rickets and pneumonia had worse outcomes.


CONCLUSIONS
Rotavirus gastroenteritis has a long hospital stay and a high mortality. Children in shock on admission and those with co-morbid conditions should get priority for they have a poor outcome.
Department of Paediatrics and Child Health, Aga Khan University Hospital, Nairobi, P.O. Box 30270 - 00100, Nairobi, Kenya.
B O
BO
Osano
R W
RW
Kamenwa
D
D
Wamalwa
J K
JK
Wangombe
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006760:Hospitalization; D006801:Humans; D007630:Kenya; D008137:Longitudinal Studies; D008297:Male; D012400:Rotavirus Infections / Q000150:complications / Q000175:diagnosis* / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome