Donor-derived infection: epidemiology and outcomes.
Over the past decade, the solid organ transplant community has focused increased attention on unexpected transmission of infectious pathogens from organ donor to recipient. While unexpected donor-derived infections are relatively uncommon, recent cases of transmission of human immunodeficiency virus (HIV) and hepatitis C to multiple recipients, as well as transmission of HIV from a living donor, have further increased interest in improving the safety of solid organ transplantation. This article will review the epidemiology and outcomes associated with unexpected donor-derived infection. Furthermore, the reporting and patient safety process will be discussed, as will preventative measures that can reduce the burden of donor-derived infection.
Department of Internal Medicine, Division of Infectious Diseases, University of Michigan Medical School, 3120 Taubman Center; 1500 E. Medical Center Dr., SPC 5378, Ann Arbor, MI, 48109-5378, USA, kauld@umich.edu.
Daniel R
DR
Kaul