Intravitreal injections: a review of the evidence for best practice.
Intravitreal injection is a common procedure performed by ophthalmologists. It is a quick and targeted treatment for a number of ophthalmic conditions. Despite this, the potential to cause serious complications and patient discomfort cannot be ignored. This article presents the level of evidence in the scientific literature supporting common practices such as location of the procedure, anaesthetic choice, sterile procedure techniques, comparison of some common pharmaceutical agents and the use of antibiotics.
Medical Retina Unit, Royal Victorian Eye and Ear Hospital; Centre for Eye Research Australia, University of Melbourne, Melbourne, VIC 3002, Australia. xavier.fagan@eyeandear.org.au
Xavier J
XJ
Fagan
Salmaan
S
Al-Qureshi
D000779:Anesthetics, Local / Q000008:administration & dosage; D020533:Angiogenesis Inhibitors / Q000008:administration & dosage*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000985:Antisepsis / Q000379:methods; D004203:Disinfection / Q000379:methods; D006801:Humans; D058449:Intravitreal Injections / Q000379:methods*; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors; D014822:Vitreous Body / Q000187:drug effects*
D000779:Anesthetics, Local; D020533:Angiogenesis Inhibitors; D000900:Anti-Bacterial Agents; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A