Prevalence and correlates of genital warts in Kenyan female sex workers.
BACKGROUND
Our goal in the present study was to investigate the prevalence and correlates of genital warts in a population of female sex workers in Mombasa, Kenya. Because of the high prevalence of human immunodeficiency virus type 1 (HIV-1) in this population, we were particularly interested in the association between HIV-1 infection and genital warts.


METHODS
We conducted a cross-sectional study of the prevalence and correlates of genital warts among high-risk women in Mombasa, Kenya. Between 2001 and 2007, 1182 women were enrolled, of whom 613 (51.4%) were HIV-1 seropositive. Chi square tests and logistic regression were used to examine the associations between genital warts and potential correlates.


RESULTS
Genital warts were identified on clinical examination in 27 (2.3%) women. Women who were HIV-1 seropositive were nearly 8 times as likely to have genital warts compared with HIV-1-seronegative women (odds ratio, 7.69; 95% confidence interval, 2.30-25.6).


CONCLUSIONS
Understanding the prevalence and correlates of genital warts will help to determine whether coverage for the wart-inducing subtypes 6 and 11 in a human papillomavirus vaccine is an important consideration in resource-limited countries.
University of Washington, Seattle, WA, USA.
Barbara E
BE
Kavanaugh
Katherine
K
Odem-Davis
Walter
W
Jaoko
Benson
B
Estambale
James N
JN
Kiarie
Linnet N
LN
Masese
Ruth
R
Deya
Lisa E
LE
Manhart
Susan M
SM
Graham
Raymond Scott
RS
McClelland
D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology* / Q000517:prevention & control; D000328:Adult; D052685:Alphapapillomavirus / Q000187:drug effects / Q000276:immunology / Q000302:isolation & purification*; D016009:Chi-Square Distribution; D003218:Condylomata Acuminata / Q000453:epidemiology* / Q000517:prevention & control; D003430:Cross-Sectional Studies; D005260:Female; D005831:Genital Diseases, Female / Q000453:epidemiology* / Q000517:prevention & control; D005836:Genitalia, Female / Q000821:virology*; D006801:Humans; D007630:Kenya / Q000453:epidemiology; D016015:Logistic Models; D053918:Papillomavirus Vaccines / Q000494:pharmacology; D010808:Physical Examination; D015995:Prevalence; D012307:Risk Factors; D060386:Sex Workers
D053918:Papillomavirus Vaccines