A fragment-based approach toward substituted trioxa[7]helicenes.
A series of novel substituted trioxa[7]helicenes have been successfully prepared by a one-pot palladium catalyzed C-H arylation reaction starting from readily prepared dibenzofuran fragments. The dinitro-substituted helicene was analyzed by X-ray crystallography revealing the occurrence of two distinct enantiomers in the asymmetric unit, which forms interesting supramolecular motifs in the crystal, based on weak H-bonding interactions.
Molecular Design and Synthesis, Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001 Leuven, Belgium.
Hans
H
Kelgtermans
Liliana
L
Dobrzańska
Luc
L
Van Meervelt
Wim
W
Dehaen
D002384:Catalysis; D006860:Hydrogen Bonding; D008958:Models, Molecular; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D011083:Polycyclic Compounds / Q000138:chemical synthesis*
D011083:Polycyclic Compounds; C031660:helicenes; D010165:Palladium; D010100:Oxygen