Use of plasma rich in growth factor for schneiderian membrane management during maxillary sinus augmentation procedure.
The aim of this pilot study was to present a novel technique for the management of the Schneiderian membrane during maxillary sinus lift surgery using plasma rich in growth factors (PRGF). Eight maxillary sinuses were augmented in 8 patients. Two small perforations of the Schneiderian membrane occurred during the lifting procedure, which were solved using the PRGF clot before grafting the site with PRGF and anorganic bovine bone. With the exception of 1 patient who experienced pain following an acute sinus infection after 3 days of uneventful healing, the patients' postoperative quality of life was generally good. The most common complication (50% of cases) was hematoma, which disappeared after 1 week. Despite the limitations of this study concerning the sample size and the study design, the use of PRGF may be helpful in reducing complications following sinus lift surgery. More well-designed studies, with larger sample size, are needed to validate this protocol.
Università degli Studi di Milano, Department of Health Technologies, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.
Silvio
S
Taschieri
Stefano
S
Corbella
Massimo
M
Del Fabbro
D000328:Adult; D000368:Aged; D016301:Alveolar Bone Loss / Q000601:surgery* / Q000628:therapy; D000540:Alveolar Ridge Augmentation / Q000379:methods; D001684:Biological Dressings; D005260:Female; D006133:Growth Substances / Q000008:administration & dosage* / Q000302:isolation & purification / Q000502:physiology; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000008:administration & dosage / Q000302:isolation & purification; D007575:Jaw, Edentulous / Q000534:rehabilitation / Q000601:surgery; D008297:Male; D008437:Maxilla / Q000601:surgery; D008443:Maxillary Sinus / Q000601:surgery; D008875:Middle Aged; D009297:Nasal Mucosa / Q000293:injuries* / Q000502:physiology; D013516:Oral Surgical Procedures, Preprosthetic / Q000379:methods; D010865:Pilot Projects; D053657:Platelet-Rich Plasma / Q000737:chemistry / Q000502:physiology*; D011446:Prospective Studies; D059546:Sinus Floor Augmentation / Q000379:methods*; D016896:Treatment Outcome
D006133:Growth Substances; D036341:Intercellular Signaling Peptides and Proteins