The CAMERA (Computer-Assisted Management in Early Rheumatoid Arthritis) studies.
The history, main issues and results of the two tight control CAMERA (Computer-Assisted Management in Early Rheumatoid Arthritis) studies are described. The first CAMERA study showed favourable and superior effects of a tight control methotrexate-based strategy, compared to that of a conventional methotrexate-based strategy. In CAMERA-II, the results were even better when adding 10 mg prednisone daily for 2 years to the methotrexate-based, tight control strategy. In all, the CAMERA studies have shown good results in the treatment of early RA patients with conventional anchor drugs, aiming for remission, making use of a feasible and simple computer decision program.
Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands. j.w.g.jacobs@umcutrecht.nl
Johannes W G
JW
Jacobs
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D003658:Decision Making, Computer-Assisted; D018450:Disease Progression; D004359:Drug Therapy, Combination; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D010347:Patient Care Planning; D011241:Prednisone / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D012074:Remission Induction; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents; D011241:Prednisone; D008727:Methotrexate