Nonfatal suicidal overdose of olanzapine in an adolescent.
The atypical antipsychotic olanzapine is increasingly being used for various psychiatric conditions. There are few reports of olanzapine overdose in adolescent population. We report a case of 16-year-old adolescent who ingested 750 mg olanzapine, the highest reported nonlethal dose of olanzapine in adolescents. He presented with tachycardia, hypotension, generalized myoclonus, hyperpyrexia, muscular rigidity, leukocytosis and elevated creatine phosphokinase (CPK) levels. He recovered from the toxicity with minimal intervention.
Department of Psychiatry, Pandit Jawaharlal Nehru Memorial Medical College & Dr. Bhimrao Ambedkar MemorialHospital, Raipur, Chhattisgarh 492001, India.
Lokesh Kumar
LK
Singh
Samir Kumar
SK
Praharaj
Manoj
M
Sahu
D000293:Adolescent; D014150:Antipsychotic Agents / Q000506:poisoning*; D001569:Benzodiazepines / Q000506:poisoning*; D004305:Dose-Response Relationship, Drug; D062787:Drug Overdose; D006801:Humans; D008297:Male; D000077152:Olanzapine; D013406:Suicide, Attempted
D014150:Antipsychotic Agents; D001569:Benzodiazepines; D000077152:Olanzapine