Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012.
Coronaviruses have the potential to cause severe transmissible human disease, as demonstrated by the severe acute respiratory syndrome (SARS) outbreak of 2003. We describe here the clinical and virological features of a novel coronavirus infection causing severe respiratory illness in a patient transferred to London, United Kingdom, from the Gulf region of the Middle East.
Health Protection Agency (HPA), London, UK.
A
A
Bermingham
M A
MA
Chand
C S
CS
Brown
E
E
Aarons
C
C
Tong
C
C
Langrish
K
K
Hoschler
K
K
Brown
M
M
Galiano
R
R
Myers
R G
RG
Pebody
H K
HK
Green
N L
NL
Boddington
R
R
Gopal
N
N
Price
W
W
Newsholme
C
C
Drosten
R A
RA
Fouchier
M
M
Zambon
D000818:Animals; D017934:Coronavirus / Q000145:classification / Q000302:isolation & purification* / Q000472:pathogenicity; D018352:Coronavirus Infections / Q000175:diagnosis* / Q000382:microbiology / Q000821:virology; D018563:Disease Notification; D004197:Disease Reservoirs; D020869:Gene Expression Profiling; D006801:Humans; D007362:Intensive Care Units; D008131:London; D008297:Male; D008875:Middle Aged; D010360:Patient Transfer; D060888:Real-Time Polymerase Chain Reaction; D012131:Respiratory Insufficiency / Q000150:complications / Q000628:therapy; D012529:Saudi Arabia; D012680:Sensitivity and Specificity; D045169:Severe Acute Respiratory Syndrome / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D014195:Travel