Y-site compatibility of medications with parenteral nutrition.
Providing parenteral nutrition to pediatric patients requiring various other intravenous products can be challenging. Evaluation of compatibility is essential; however, information is limited and sometimes conflicting. We strove to critically evaluate and present the available published data as a comprehensive and practical reference. To accomplish this, we weighed the strength of evidence supporting compatibility versus incompatibility and provided specific conditions affecting compatibility, where appropriate. Many commonly used medications in pediatric patients have consistently demonstrated Y-site compatibility with parenteral nutrition and may be safely administered simultaneously. Exceptions must be noted and these medications should preferentially be administered through a separate line, if available, or the same line may be used only after stopping the parenteral nutrition infusion and flushing the line before and after drug administration.
Department of Pharmacy Practice and Administration, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, New Jersey and Department of Pharmacy and Clinical Services, Hackensack University Medical Center, Hackensack, New Jersey.
Christine A
CA
Robinson
Jaclyn E
JE
Lee