Amazing IL-9: revealing a new function for an "old" cytokine.
The incidence of melanoma - the most aggressive form of skin cancer - is dramatically increasing, while the development of innovative therapeutic strategies continues to be challenging, especially due to a lack of knowledge about the molecular mechanisms underlying melanoma progression as well as antitumor immunity. In this issue of the JCI, Yong Lu and colleagues report a central role for Th9 cells in antitumor immunity.
Institute for Immunology, University Medical Centre, Johannes Gutenberg University Mainz, Mainz, Germany.
Edgar
E
Schmitt
Tobias
T
Bopp
D000818:Animals; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology*; D007111:Immunity, Cellular; D016906:Interleukin-9 / Q000276:immunology*; D008175:Lung Neoplasms / Q000276:immunology*; D008545:Melanoma / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*
D016906:Interleukin-9