A case of cystoid macular edema associated with Paclitaxel chemotherapy.
We encountered a patient with cystoid macular edema (CME) secondary to paclitaxel use. A 57-year-old man presented with gradual decreased bilateral vision. His chemotherapeutic regimen consisted of bevacizumab, paclitaxel (175 mg/m(2) for 5 months), and carboplatin. Optical coherence tomography imaging revealed bilateral CME greater than 500 µm. However, one year later, visual acuity was improved, best-corrected Snellen visual acuity was 40 / 80 in each eye, and CME was spontaneously improved. Our study confirmed that macular edema associated with paclitaxel use shows spontaneous resolution and improvement of visual acuity after a change of chemotherapeutic regimen.
Department of Ophthalmology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Dong Sik
DS
Ham
Joo Eun
JE
Lee
Hyun Woong
HW
Kim
Il Han
IH
Yun
D000230:Adenocarcinoma / Q000188:drug therapy; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy; D008269:Macular Edema / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D017239:Paclitaxel / Q000009:adverse effects*; D012075:Remission, Spontaneous; D041623:Tomography, Optical Coherence; D014792:Visual Acuity
D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel