[Cardiac tamponade due to pericardial metastasis from renal cell carcinoma : a case report].
A 52-year-old man received partial left nephrectomy for renal cell carcinoma (clear cell carcinoma, G1, pT1aN0M0) in January, 2003. After 7 years, he was diagnosed with mediastinal lymph node metastasis and we performed interferon-alpha therapy. After 7 months, he presented with dyspnea. Chest X rays showed a large globular cardiac shadow. Echocardiography revealed massive pericardial effusion with features of cardiac tamponade. Under echocardiographic guidance, 1, 020 ml hemorrhagic pericardial fluid was aspirated ; the fluid revealed class V and our diagnosis was pericardial metastasis of renal cell carcinoma. We performed treatment with sunitinib for 5 months after pericardiocectesis. Metastatic mediastinal lymph node size was maintained showing stable disease by computed tomography and cardiac effusion was not increased, but he died unexpectedly at home.
The Department of Urology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan.
Norichika
N
Ueda
Yasuyuki
Y
Arai
Kyosuke
K
Matsuzaki
Yoshiyuki
Y
Yamamoto
Ken
K
Takeda
Wataru
W
Nakata
Masashi
M
Nakayama
Kenichi
K
Kakimoto
Kazuo
K
Nishimura
D000970:Antineoplastic Agents / Q000627:therapeutic use; D002292:Carcinoma, Renal Cell / Q000473:pathology*; D002305:Cardiac Tamponade / Q000000981:diagnostic imaging / Q000209:etiology*; D004452:Echocardiography; D006338:Heart Neoplasms / Q000150:complications* / Q000556:secondary* / Q000628:therapy; D006801:Humans; D007211:Indoles / Q000627:therapeutic use; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D020519:Pericardiocentesis; D010496:Pericardium; D011758:Pyrroles / Q000627:therapeutic use; D000077210:Sunitinib
D000970:Antineoplastic Agents; D007211:Indoles; D011758:Pyrroles; D000077210:Sunitinib