Kinetics of acetaminophen degradation by Fenton oxidation in a fluidized-bed reactor.
Acetaminophen (ACT), an analgesic and antipyretic substance, is one of the most commonly detected pharmaceutical compound in surface waters and wastewaters. In this study, fluidized-bed Fenton (FB-Fenton) was used to decompose ACT into its final degradation products. The 1.45-L cylindrical glass reactor had inlet, outlet and recirculating sections. SiO(2) carrier particles were supported by glass beads with 2-4 mm in diameter. ACT concentration was determined by high performance liquid chromatography (HPLC). During the first 40 min of reaction, a fast initial ACT removal was observed and the "two-stage" ACT degradation conformed to a pseudo reaction kinetics. The effects of ferrous ion dosage and [Fe(2+)]/[H(2)O(2)] (FH ratio) were integrated into the derived pseudo second-order kinetic model. A reaction pathway was proposed based on the intermediates detected through SPME/GC-MS. The aromatic intermediates identified were hydroquinone, benzaldehydes and benzoic acids while the non-aromatic substances include alcohols, ketones, aldehydes and carboxylic acids. Rapid initial ACT degradation rate can be accomplished by high initial ferrous ion concentration and/or low FH ratio.
Environmental Engineering Graduate Program, University of the Philippines, 1101 Diliman, Quezon City, Philippines.
Mark Daniel G
MD
de Luna
Rowena M
RM
Briones
Chia-Chi
CC
Su
Ming-Chun
MC
Lu
D000082:Acetaminophen / Q000032:analysis / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry*; D017745:Incineration / Q000379:methods*; D007501:Iron / Q000737:chemistry*; D007700:Kinetics; D014865:Waste Disposal, Fluid / Q000379:methods; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000737:chemistry*
D014874:Water Pollutants, Chemical; D000082:Acetaminophen; D006861:Hydrogen Peroxide; D007501:Iron