Juvenile trabecular ossifying fibroma: an update.
Fibro-osseous lesions are characterized by the presence of bone marrow that has changed into fibrous tissue and that contains mineralized material of varying appearances. Because of overlapping clinical, radiological, and histopathological features, their classification has evoked much discussion. The current classification recognizes fibrous dysplasia, ossifying fibroma, and osseous dysplasia. Juvenile trabecular ossifying fibroma is a rare variant of ossifying fibroma that is clinically characterized by rapid growth that may suggest malignancy. A series of 15 cases is reported with emphasis on a hitherto unnoticed histological feature that may be helpful in recognizing this lesion.
Department of Pathology 824, Radboud University Nijmegen Medical Center, 6500 HB, Nijmegen, Netherlands. p.slootweg@pathol.umcn.nl
Pieter J
PJ
Slootweg
D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D018214:Fibroma, Ossifying / Q000473:pathology*; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology; D008441:Maxillary Neoplasms / Q000473:pathology