Progressive chronic lymphocytic leukemia after allogeneic hematopoietic cell transplantation.
This case report presents a patient with poor-prognosis chronic lymphocytic leukemia (CLL) who was treated with chemotherapy and underwent allogeneic hematopoietic cell transplant (alloHCT) but ultimately progressed. The application of the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for CLL and the impact of alloHCT on secondary therapy for progressive CLL are discussed.
Department of Medicine, BMT Program, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
Potjana
P
Jitawatanarat
Arpita
A
Desai
Pradeep
P
Sharda
Hong
H
Liu
Maureen
M
Ross
Francisco J
FJ
Hernandez-Llizaliturri
Philip L
PL
McCarthy
George L
GL
Chen
D018450:Disease Progression; D017809:Fatal Outcome; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D018365:Neoplasm, Residual; D014184:Transplantation, Homologous