Fluorescent polymeric micelles with tetraphenylethylene moieties and their application for the selective detection of glucose.
By linking TPE moieties that exhibit aggregation-induced (enhanced) emission to the amphiphilic copolymer 1, fluorescent micelles are prepared and characterized. The polymeric micelles exhibit relatively strong fluorescence which can be tuned by heating and cooling. By combining cascaded enzymatic (oxidation of D-glucose with GOx) and chemical (oxidation of I(-)  by H(2) O(2) ) reactions, the fluorescent micelles of copolymer 1 are successfully utilized for the selective detection of D-glucose in aqueous solution. The influences of proteins (e.g., bovine serum albumin) and reductants (e.g., ascorbic acid) on this fluorescence detection of D-glucose are also discussed.
Organic Solids Laboratory and State Key Laboratory of Polymer Physics and Chemistry, Institute of Chemistry, Beijing National Laboratory for Molecular Sciences, Chinese Academy of Sciences, Beijing 100190, China.
Xiang
X
Shen
Yi
Y
Shi
Bo
B
Peng
Kan
K
Li
Junfeng
J
Xiang
Guanxin
G
Zhang
Zitong
Z
Liu
Yongming
Y
Chen
Deqing
D
Zhang
D001205:Ascorbic Acid / Q000737:chemistry; D005030:Ethylenes / Q000737:chemistry*; D005456:Fluorescent Dyes; D005947:Glucose / Q000032:analysis*; D006861:Hydrogen Peroxide / Q000737:chemistry; D008823:Micelles; D010084:Oxidation-Reduction; D011108:Polymers / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry; D012996:Solutions; D013050:Spectrometry, Fluorescence; D013501:Surface-Active Agents / Q000737:chemistry*; D014867:Water
D005030:Ethylenes; D005456:Fluorescent Dyes; D008823:Micelles; D011108:Polymers; D012996:Solutions; D013501:Surface-Active Agents; D014867:Water; D012710:Serum Albumin, Bovine; D006861:Hydrogen Peroxide; D005947:Glucose; D001205:Ascorbic Acid