H5N1 highly pathogenic avian influenza virus isolated from conjunctiva of a whooper swan with neurological signs.
An H5N1 highly pathogenic avian influenza virus was isolated from conjunctiva of a whooper swan with neurological signs, which was captured during the latest H5N1 HPAI outbreak in Japan. The conjunctival swab contained a larger amount of the virus in comparison with the tracheal swab. This is the first report on H5N1 virus isolation from the conjunctiva of a wild bird, and the result may suggest the conjunctival swab to be a critical sample for H5N1 HPAIV detection in waterfowl. Phylogenetic analysis of the HA gene indicated that the virus falls into H5N1 clade 2.3.2.1.
Research Center for Animal Hygiene and Food Safety, Obihiro University of Agriculture and Veterinary Medicine, 2-11 Inada, Obihiro, Hokkaido, 080-8555, Japan.
Vuong N
VN
Bui
Haruko
H
Ogawa
Lai H
LH
Ngo
Tugsbaatar
T
Baatartsogt
Lary N B
LN
Abao
Shio
S
Tamaki
Keisuke
K
Saito
Yukiko
Y
Watanabe
Jonathan
J
Runstadler
Kunitoshi
K
Imai
D000818:Animals; D001715:Bird Diseases / Q000175:diagnosis* / Q000821:virology*; D001717:Birds; D016000:Cluster Analysis; D003228:Conjunctiva / Q000821:virology; D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000235:genetics; D053124:Influenza A Virus, H5N1 Subtype / Q000302:isolation & purification*; D005585:Influenza in Birds / Q000175:diagnosis* / Q000821:virology*; D007564:Japan; D008969:Molecular Sequence Data; D009422:Nervous System Diseases / Q000175:diagnosis* / Q000821:virology*; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D014132:Trachea / Q000821:virology; D019562:Viral Load
D019267:Hemagglutinin Glycoproteins, Influenza Virus; C109963:hemagglutinin, avian influenza A virus