Exposures to 1,3-dimethylamylamine-containing products reported to Texas poison centers.
1,3-Dimethylamylamine (DMAA) is an ingredient in a number of weight loss and exercise performance enhancing products. However, information on the safety of DMAA-containing products is limited. Exposures to DMAA-containing products reported to Texas poison centers during 2010-2011 were identified and selected factors were examined. A total of 56 exposures were found, of which 75.0% were reported during 2011. OxyElite Pro™ was the reported product in 80.4% of the exposures. The patients were 51.8% male and 55.4% age ≤5 years. The patient was managed on site (such as at home) in 57.1% of the cases, and the exposure was known or expected to result in an outcome that was classified as not serious in 80.4%. The most frequently reported clinical effects were tachycardia (28.6%), nausea (16.1%), and vomiting (12.5%). The most common treatments were dilution (41.1%), food (19.6%), and activated charcoal (14.3%). It should be noted that the adverse clinical effects may be due to other ingredients in the DMAA-containing products, such as caffeine.
Epidemiology and Disease Surveillance Unit, Texas Department of State Health Services, Austin, Texas 78756, USA. matthias.forrester@dshs.state.tx.us
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D000293:Adolescent; D000328:Adult; D000588:Amines / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D019587:Dietary Supplements / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009325:Nausea / Q000139:chemically induced; D011039:Poison Control Centers / Q000706:statistics & numerical data*; D013610:Tachycardia / Q000139:chemically induced; D013781:Texas; D014839:Vomiting / Q000139:chemically induced; D055815:Young Adult
C571979:1,3-dimethylamylamine; D000588:Amines