Bioactive oleanane, lupane and ursane triterpene acid derivatives.
Betulinic, ursolic and oleanolic acids isolated from the aerial parts of Eriope blanchetii (Lamiaceae) were subjected to different esterification reactions, yielding 12 C-3 position ester derivatives. All compounds were identified using spectroscopic techniques, such as IR, 1H-NMR and MS. The derivatives were further investigated for their antioxidant level, Artemia salina lethality and antimicrobial activity.
Faculdade de Farmácia, Universidade Federal da Bahia, Rua Barão de Geremoabo, s/n, 41810-290, Salvador, BA, Brazil. lurdinhafarma@yahoo.com.br
Maria de L
Mde L
e Silva
Juceni P
JP
David
Lidércia C R C
LC
Silva
Rauldenis A F
RA
Santos
Jorge M
JM
David
Luciano S
LS
Lima
Pedro S
PS
Reis
Renato
R
Fontana
D000818:Animals; D001156:Artemia / Q000187:drug effects; D004952:Esters / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry / Q000494:pharmacology; D019686:Lamiaceae / Q000737:chemistry; D019906:Nuclear Magnetic Resonance, Biomolecular; D009828:Oleanolic Acid / Q000737:chemistry / Q000494:pharmacology*; D053978:Pentacyclic Triterpenes; D010936:Plant Extracts / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry / Q000494:pharmacology*; D000094062:Betulinic Acid; D000097245:Ursolic Acid
D004952:Esters; D016166:Free Radical Scavengers; D009828:Oleanolic Acid; D053978:Pentacyclic Triterpenes; D010936:Plant Extracts; D014315:Triterpenes; D000094062:Betulinic Acid; D000097245:Ursolic Acid