Pulmonary hypertension associated with congenital heart disease: a practical review for the pediatric cardiologist.
Pulmonary hypertension (PH) is a complex condition with a broad range of etiologies that result in a common outcome--elevated pulmonary arterial pressure. For the pediatric cardiologist, this entity provides a manifest demonstration of the interrelationship of cardiac and pulmonary physiology. A thoughtful approach must be applied to each patient with PH in order to achieve a thorough understanding of the nature of disease and to proceed with individualized therapy in an appropriate and timely manner. This article aims to provide a clinically relevant, practical review of current literature related to PH in patients with congenital heart disease, including the causes, diagnostic considerations, and an overview of management.
Pediatrics, Texas Children's Hospital/Baylor College of Medicine, Houston, Tex, USA. wbkyle@bcm.edu
W Buck
WB
Kyle
D000367:Age Factors; D062186:Arterial Pressure; D006330:Heart Defects, Congenital / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D011379:Prognosis; D011651:Pulmonary Artery / Q000503:physiopathology*; D012307:Risk Factors; D014661:Vasoconstriction