Preliminary results of the first human uterus transplantation from a multiorgan donor.
OBJECTIVE
To describe the first-year results of the first human uterus transplantation case from a multiorgan donor.


METHODS
Case study.


METHODS
University hospital.


METHODS
A 21-year-old woman with complete müllerian agenesis who had been previously operated on for vaginal reconstruction.


METHODS
Uterus transplantation procedure consisting of orthotopic replacement and fixation of the retrieved uterus, revascularization, end to site anastomoses of bilateral hypogastric arteries and veins to bilateral external iliac arteries and veins was performed.


METHODS
Resumption of menstrual cycles.


RESULTS
The patient had menarche 20 days after transplant surgery. She has had 12 menstrual cycles since the operation.


CONCLUSIONS
We have described the longest-lived transplanted human uterus to date with acquirement of menstrual cycles.
Department of Plastic Surgery, Akdeniz University, Antalya, Turkey.
Omer
O
Ozkan
Munire Erman
ME
Akar
Ozlenen
O
Ozkan
Okan
O
Erdogan
Necmiye
N
Hadimioglu
Murat
M
Yilmaz
Filiz
F
Gunseren
Mehmet
M
Cincik
Elif
E
Pestereli
Huseyin
H
Kocak
Derya
D
Mutlu
Ayhan
A
Dinckan
Omer
O
Gecici
Gamze
G
Bektas
Gultekin
G
Suleymanlar
D000714:Anastomosis, Surgical / Q000379:methods; D005260:Female; D006801:Humans; D008597:Menstrual Cycle / Q000502:physiology; D010865:Pilot Projects; D009927:Tissue and Organ Procurement; D016896:Treatment Outcome; D014599:Uterus / Q000002:abnormalities* / Q000502:physiology / Q000601:surgery / Q000637:transplantation*; D014621:Vagina / Q000002:abnormalities* / Q000601:surgery*; D055815:Young Adult