Excision with corneoscleral lamellar keratoplasty and amniotic membrane transplantation of a corneal displaced recurrent conjunctival melanoma.
An 81-year-old woman with a raised pigmented nodule over her left cornea for 7 months duration was examined. Dark conjunctival pigmentation was observed in the upper bulbar fornix conjunctiva. She had previously undergone primary surgical excision of a malignant conjunctival melanoma four years earlier. The tumor separated easily from the corneal surface, but remained slightly attached to the corneoscleral surface. A corneoscleral lamellar dissection of 3 mm in width and 2 mm in depth as well as a corneoscleral lamellar keratoplasty for the reconstruction of the corneoscleral defect were performed. The wide upper bulbar and fornix conjunctiva were excised, and an amniotic membrane transplantation was performed. Biopsy revealed an invasive melanoma with a depth of 1 mm. Left, right, and inferior tumor margins of the corneoscleral lesion and the pigmentary lesion in the conjunctiva were free of the tumor. After surgery, 0.04% mitomycin was administered topically 4 times daily for 4 weeks. There was no recurrence 2 years after surgery, and systemic evaluation revealed no metastasis.
Department of Ophthalmology & Visual Science, The Catholic University of Korea College of Medicine, Seoul, Korea.
Eun Chul
EC
Kim
Man Soo
MS
Kim
Nam Yeo
NY
Kang
D000369:Aged, 80 and over; D000650:Amnion / Q000637:transplantation*; D003230:Conjunctival Neoplasms / Q000601:surgery*; D016039:Corneal Transplantation; D005260:Female; D006801:Humans; D008545:Melanoma / Q000601:surgery*; D009364:Neoplasm Recurrence, Local; D012008:Recurrence