[Adaptive function of the brain and problems of hypoxia].
Based on the findings of various authors and own experimental data it was concluded that adaptive behaviour is regulated by changing in the level of spontaneous neuronal activity. Spontaneous firing is monitored by brain metabolic M-cholinergic reaction which increased the efficacy of dendritic propagation by mechanism of K+ membrane channels blockade. High energy demands of cholinergic process creates a threat to nerve cells survival in hypoxic conditions.
Iu S
IuS
Mednikova
S N
SN
Kozhechkin
F V
FV
Kopytova
O Kh
OKh
Koshtoiants
D000109:Acetylcholine / Q000378:metabolism*; D000222:Adaptation, Physiological; D000818:Animals; D001921:Brain / Q000378:metabolism / Q000503:physiopathology*; D004734:Energy Metabolism / Q000502:physiology; D006801:Humans; D002534:Hypoxia, Brain / Q000378:metabolism / Q000503:physiopathology*; D008564:Membrane Potentials / Q000502:physiology; D009474:Neurons / Q000378:metabolism / Q000502:physiology*
D000109:Acetylcholine