The PaAlr1 magnesium transporter is required for ascospore development in Podospora anserina.
The PaAlr1 gene encoding a putative plasma membrane magnesium (Mg) transporter in Podospora anserina was inactivated. The PaAlr1(Δ) mutants showed sensitivity to deprivation and excess Mg(2+) and Ca(2+). They also exhibited an autonomous ascospore maturation defect. Mutant ascospores were arrested at an early stage when they contained two nuclei. These data emphasize the role of Mg ions during sexual development in a filamentous fungus.
Univ Paris Diderot, Sorbonne Paris Cité, Institut des Energies de Demain (IED), Paris, France.
Pierre
P
Grognet
Hervé
H
Lalucque
Philippe
P
Silar
D002118:Calcium / Q000378:metabolism; D027682:Cation Transport Proteins / Q000235:genetics / Q000378:metabolism*; D055786:Gene Knockout Techniques; D008274:Magnesium / Q000378:metabolism*; D048468:Podospora / Q000166:cytology / Q000201:enzymology* / Q000254:growth & development* / Q000378:metabolism; D013172:Spores, Fungal / Q000166:cytology / Q000201:enzymology* / Q000254:growth & development* / Q000378:metabolism
D027682:Cation Transport Proteins; D008274:Magnesium; D002118:Calcium