GalX regulates the D-galactose oxido-reductive pathway in Aspergillus niger.
Galactose catabolism in Aspergillus nidulans is regulated by at least two regulators, GalR and GalX. In Aspergillus niger only GalX is present, and its role in d-galactose catabolism in this fungus was investigated. Phenotypic and gene expression analysis of a wild type and a galX disruptant revealed that GalX regulates the d-galactose oxido-reductive pathway, but not the Leloir pathway in A. niger.
Microbiology & Kluyver Centre for Genomics of Industrial Fermentation, Utrecht University, Utrecht, The Netherlands.
Birgit S
BS
Gruben
Miaomiao
M
Zhou
Ronald P
RP
de Vries
D001234:Aspergillus niger / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D002874:Chromosome Mapping; D015825:Chromosomes, Fungal / Q000235:genetics; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism*; D005690:Galactose / Q000378:metabolism*; D020869:Gene Expression Profiling; D015966:Gene Expression Regulation, Fungal; D053858:Metabolic Networks and Pathways; D009154:Mutation; D020411:Oligonucleotide Array Sequence Analysis; D009844:Oligosaccharides / Q000378:metabolism; D010084:Oxidation-Reduction; D011134:Polysaccharides / Q000378:metabolism
D005656:Fungal Proteins; D009844:Oligosaccharides; D011134:Polysaccharides; D005690:Galactose