[Thyroid function and serum lipids of adults living in areas of excessive iodine in water in Hebei province].
OBJECTIVE
To investigate the iodine status and the prevalence of thyroid disease and dyslipidemia in adults living in areas of excessive iodine in water in Hebei Province, and to explore the impact of excessive iodine intake on dyslipidemia.


METHODS
Subjects were selected from Haixing County in Cangzhou, Hebei. Fasting morning urine and venous blood were collected to test the levels of urinary iodine and serum free triiodothyronine (FT3), free thyroxine (FT4), and sensitive thyroid-stimulating hormone (sTSH). Thyroid peroxidase antibody (TPOAb), thyroglobulin antibody (TGAb) and total cholesterol (CHO), triglyceride (TG), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) were also measured.


RESULTS
The median of urinary iodine was 1094.92 (627.38 - 1511.81) microg/L. There were 66 (22.0%) adults diagnosed as thyroid disorder, including 3 (1.0%) hyperthyroidism patients, 7 (2.3%) subclinical hyperthyroidism patients, 12 (4.0%) hypothyroidism patients and 44 (14.7%) subclinical hypothyroidism patients. The levels of CHO, TG, HDL-C and LDL-C were (5.46 +/- 1.06) mmol/L, 2.19 (1.70 - 2.96) mmol/L, 1.18 (1.03 - 1.45) mmol/L and (3.08 +/- 1.05) mmol/L respectively, no significant difference was observed between the thyroid disorder patients or non-patients.


CONCLUSIONS
The prevalence of dyslipidemia in adults living in areas of excessive iodine in water was high.
Department of Nutrition and Food Hygiene, College of Public Health, Tianjin Medical University, Tianjin 300070, China. hongyezhijia@126.com
Haiqiang
H
Li
Zhongna
Z
Sang
Long
L
Tan
Na
N
Zhao
Wei
W
Wei
Guiqin
G
Zhang
Hua
H
Liu
Songchen
S
Wen
Wanqi
W
Zhang
D000328:Adult; D001323:Autoantibodies; D002681:China / Q000453:epidemiology; D050171:Dyslipidemias / Q000453:epidemiology*; D006801:Humans; D007037:Hypothyroidism; D007454:Iodides; D007455:Iodine / Q000032:analysis* / Q000378:metabolism; D008055:Lipids / Q000097:blood; D015995:Prevalence; D013959:Thyroid Diseases; D013960:Thyroid Function Tests; D013972:Thyrotropin; D013974:Thyroxine; D014284:Triiodothyronine; D014881:Water Supply
D001323:Autoantibodies; D007454:Iodides; D008055:Lipids; C006606:anti-thyroglobulin; C056626:thyroid microsomal antibodies; D014284:Triiodothyronine; D013972:Thyrotropin; D007455:Iodine; D013974:Thyroxine