Use of sugammadex in a patient with amyotrophic lateral sclerosis.
OBJECTIVE
To report on general anesthesia management in amyotrophic lateral sclerosis.


METHODS
A 47-year-old man presented with fracture of the humerus. The patient was diagnosed with amyotrophic lateral sclerosis. General anesthesia was induced with propofol, rocuronium and remifentanil. After uneventful surgical repair, TOF (train-of-four) ratio reached >0.90 at the end of operation. However, muscle strength and tidal volume were inadequate. After sugammadex 2 mg kg(-1) i.v. was given, the patient was extubated 120 s later.


CONCLUSIONS
This case highlights that rocuronium and sugammadex can be used safely in patients with amyotrophic lateral sclerosis undergoing surgery with general anesthesia.
Department of Anesthesiology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey. ebruk@omu.edu.tr
Ebru
E
Kelsaka
Deniz
D
Karakaya
Eyüp Cağatayn
EC
Zengin
D000690:Amyotrophic Lateral Sclerosis / Q000503:physiopathology*; D000732:Androstanols / Q000008:administration & dosage*; D000762:Anesthesia Recovery Period; D000768:Anesthesia, General / Q000379:methods*; D050723:Fractures, Bone / Q000601:surgery; D006801:Humans; D006811:Humerus / Q000601:surgery; D008297:Male; D008875:Middle Aged; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage*; D019637:Orthopedic Procedures / Q000379:methods; D061214:Patient Safety; D000077123:Rocuronium; D000077122:Sugammadex; D047408:gamma-Cyclodextrins / Q000008:administration & dosage*
D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D000077123:Rocuronium