Pitfalls in the management of severe hyponatraemia.
The correction of severe hyponatraemia is complicated by practical and theoretical limitations of formulae used to predict response to treatment, and random errors in the measurement of sodium concentration. We report the case of an elderly woman with a symptomatic serum sodium concentration of 93 mmol/l. Correction of serum sodium unintentionally exceeded conventional targets but, as in the majority of such cases, there were no neurological sequelae.
John Radcliffe Adult Intensive Care Unit and Oxford Kidney Unit, Oxford University Hospitals NHS Trust, Oxford, UK.
Clare
C
MacEwen
Peter
P
Watkinson
D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000009:adverse effects; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D007010:Hyponatremia / Q000139:chemically induced / Q000175:diagnosis* / Q000628:therapy*; D049993:Sodium Chloride Symporter Inhibitors / Q000009:adverse effects
D000959:Antihypertensive Agents; D049993:Sodium Chloride Symporter Inhibitors