HBB loss of heterozygosity in the hemopoietic lineage gives rise to an unusual sickle-cell trait phenotype.
Unité de Pathologie Moléculaire du Globule Rouge, Fédération de Biochimie et de Biologie Spécialisée, Hôpital Edouard Herriot, Hospices Civils and Université Claude Bernard-Lyon 1, Lyon, France. philippe.joly@chu-lyon.fr
Philippe
P
Joly
Caroline
C
Schluth-Bolard
Philippe
P
Lacan
Claire
C
Barro
Serge
S
Pissard
Audrey
A
Labalme
Damien
D
Sanlaville
Catherine
C
Badens
D000328:Adult; D019070:Cell Lineage / Q000235:genetics*; D005260:Female; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006801:Humans; D019656:Loss of Heterozygosity / Q000235:genetics*; D010641:Phenotype; D012805:Sickle Cell Trait / Q000175:diagnosis* / Q000235:genetics*
D006455:Hemoglobins, Abnormal