Investigating the feasibility of using a grit blasting process to coat nitinol stents with hydroxyapatite.
This study investigates the feasibility of utilising a grit blasting process to coat three nitinol substrates (a planer 2D surface, a circular wire and a cardiovascular stent geometry) with a hydroxyapatite coating. Surface characteristics of the coating on the three substrates were determined and additionally the durability of the coating post fatigue testing was analysed. The coating process resulted in a consistent covering of the substrate that resulted in an extremely hydrophilic stent surface. The surface roughness was dependant on grit blasting particle size. A general trend of smaller particle size resulted in a lower surface roughness, while particle size did not have an effect on the hydroxyapatite coating thickness. Fatigue integrity tests that simulated 16 months implantation demonstrated minimal damage to the coating. In conclusion we demonstrated the initial feasibility of using a grit blasting method to produce a consistent, hydrophilic, and durable HAp stent coating that has the capability of incorporating a drug eluting function.
Trinity Centre for Bioengineering, School of Engineering, Trinity College Dublin, Dublin 2, Ireland.
F
F
Keady
B P
BP
Murphy
D000497:Alloys / Q000737:chemistry*; D020099:Coated Materials, Biocompatible; D017886:Durapatite / Q000737:chemistry*; D005240:Feasibility Studies; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D013052:Spectrometry, X-Ray Emission; D015607:Stents; D013499:Surface Properties
D000497:Alloys; D020099:Coated Materials, Biocompatible; C013616:nitinol; D017886:Durapatite