Agrimonia eupatoria tea consumption in relation to markers of inflammation, oxidative status and lipid metabolism in healthy subjects.
Phytotherapy reports strong anti-oxidative and anti-inflammatory potential of agrimony (Agrimonia eupatoria L.). However the effects of agrimony tea consumption are not scientifically proven in humans. We investigated the effects of one month's consumption of agrimony tea in healthy volunteers. Significant elevation of plasma total antioxidant capacity was observed and interleukin 6 levels were significantly lowered at the end of the intervention. An improved lipid profile as estimated by increased high density lipoprotein (HDL) cholesterol was established upon agrimony tea supplementation and HDL cholesterol correlated with adiponectin levels. The results presented in this first human intervention study with agrimony tea indicate that the plant has potential in improving markers of lipid metabolism, oxidative status and inflammation in healthy adults.
Department of Biochemistry, Molecular Medicine and Nutrigenomics, Medical University Varna, Bulgaria. divanova@mu-varna.bg
Diana
D
Ivanova
Deyana
D
Vankova
Milka
M
Nashar
D000293:Adolescent; D000328:Adult; D031981:Agrimonia / Q000737:chemistry*; D000975:Antioxidants / Q000032:analysis; D001628:Beverages; D015415:Biomarkers / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D004341:Drug Evaluation; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000188:drug therapy*; D015850:Interleukin-6 / Q000097:blood; D050356:Lipid Metabolism / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress; D008517:Phytotherapy; D035261:Plant Components, Aerial / Q000737:chemistry; D010936:Plant Extracts / Q000494:pharmacology; D055815:Young Adult
D000975:Antioxidants; D015415:Biomarkers; D008076:Cholesterol, HDL; C508600:IL6 protein, human; D015850:Interleukin-6; D010936:Plant Extracts; D005947:Glucose