A unifying theory of carcinogenesis, and why targeted therapy doesn't work.
Department of Radiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33602, USA. Robert.Gillies@Moffitt.Org
Robert J
RJ
Gillies
Chris I
CI
Flowers
Jennifer S
JS
Drukteinis
Robert A
RA
Gatenby
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D063646:Carcinogenesis / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D003198:Computer Simulation; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008953:Models, Anatomic; D008954:Models, Biological; D058990:Molecular Targeted Therapy / Q000379:methods*; D017211:Treatment Failure; D059016:Tumor Microenvironment / Q000187:drug effects / Q000502:physiology*
D000970:Antineoplastic Agents