[Residual neuromuscular blockade after muscle relaxants administration in neurosurgical patients].
The paper analyzes the incidence of residual neuromuscular blockade (NMB) after pipecuronium and rocuronium administration in 124 neurosurgical patients. We analyzed neuromuscular conductance with TOF-Watch SX Residual NMB incidence after neuromuscular blocking agents administration in neurosurgical patients is 87.7%. Use of pipecuronium accompanied by a greater incidence and duration of residual NMB in comparison with rocuronium. Sugammadex administration is effective method of residual NMB reversal and can restore NMC in 3-5 minutes.
D000328:Adult; D000732:Androstanols / Q000494:pharmacology*; D001930:Brain Injuries / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019148:Neuromuscular Blockade / Q000379:methods*; D003473:Neuromuscular Nondepolarizing Agents; D019635:Neurosurgical Procedures / Q000379:methods; D017300:Pipecuronium / Q000494:pharmacology*; D000077123:Rocuronium; D000077122:Sugammadex; D013997:Time Factors; D015599:Trauma Severity Indices; D047408:gamma-Cyclodextrins / Q000494:pharmacology*
D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D047408:gamma-Cyclodextrins; D017300:Pipecuronium; D000077122:Sugammadex; D000077123:Rocuronium