Three-factor designs unable to examine the interactions (part 1).
Three-factor designs that are unable to examine the interactions include crossover design and Latin square design, which can examine three factors, namely, an experimental factor and two block factors. Although the two design types are not quite frequently used in practical research, an unexpected research effect will be achieved if they are correctly adopted on appropriate occasions. Due to the limit of space, this article introduces two forms of crossover design.
Consulting Center of Biomedical Statistics, Academy of Military Medical Sciences, Beijing 100850, China. lphu812@sina.com
Liang-ping
LP
Hu
Xiao-lei
XL
Bao
D018592:Cross-Over Studies; D005163:Factor Analysis, Statistical; D012107:Research Design