Time to act on the inadequate management of Wernicke's encephalopathy in the UK.
Wernicke's encephalopathy (WE) is a serious medical emergency whose pathogenesis is well understood and reviewed in this paper. Summarizing the evidence for its prophylaxis and management, the authors suggest that, in the UK, there is evidence that many patients identified as being at risk of WE currently do not receive appropriate treatment, despite the availability (not universal) of guidelines and protocols.
Molecular Psychiatry Laboratory, Rockefeller Building, University College London, London, UK.
Allan D
AD
Thomson
E Jane
EJ
Marshall
Derek
D
Bell
D000437:Alcoholism / Q000453:epidemiology / Q000378:metabolism / Q000628:therapy; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D019468:Disease Management; D006801:Humans; D013831:Thiamine / Q000008:administration & dosage / Q000378:metabolism; D013997:Time Factors; D006113:United Kingdom / Q000453:epidemiology; D014899:Wernicke Encephalopathy / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*
D013831:Thiamine