FluoSTIC: miniaturized fluorescence image-guided surgery system.
Over the last few years, near-infrared (NIR) fluorescence imaging has witnessed rapid growth and is already used in clinical trials for various procedures. However, most clinically compatible imaging systems are optimized for large, open-surgery procedures. Such systems cannot be employed during head and neck oncologic surgeries because the system is not able to image inside deep cavities or allow the surgeon access to certain tumors due to the large footprint of the system. We describe a miniaturized, low-cost, NIR fluorescence system optimized for clinical use during oral oncologic surgeries. The system, termed FluoSTIC, employs a miniature, high-quality, consumer-grade lipstick camera for collecting fluorescence light and a novel custom circular optical fiber array for illumination that combines both white light and NIR excitation. FluoSTIC maintains fluorescence imaging quality similar to that of current large-size imaging systems and is 22 mm in diameter and 200 mm in height and weighs less than 200 g.
Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA. sgioux@bidmc.harvard.edu
Sylvain
S
Gioux
Jean-Guillaume
JG
Coutard
Michel
M
Berger
Henri
H
Grateau
Véronique
V
Josserand
Michelle
M
Keramidas
Christian
C
Righini
Jean-Luc
JL
Coll
Jean-Marc
JM
Dinten
D000818:Animals; D005260:Female; D005336:Fiber Optic Technology / Q000295:instrumentation; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology; D051379:Mice; D008819:Mice, Nude; D008904:Miniaturization / Q000295:instrumentation*; D013050:Spectrometry, Fluorescence / Q000295:instrumentation* / Q000379:methods; D019265:Spectroscopy, Near-Infrared; D025321:Surgery, Computer-Assisted / Q000295:instrumentation* / Q000379:methods