Rationale for and clinical benefits of colonoscopy with narrow band imaging: pathological prediction and colorectal screening.
BACKGROUND
Narrow-band imaging (NBI), an emerging imaging technology, allows direct visualization of capillaries on the gastrointestinal mucosal surface. The combination of NBI and magnifying endoscopy can be used to identify morphological changes in these capillaries during the process of carcinogenesis.


CONCLUSIONS
Thus far, pathological predictions based on capillary pattern classifications have been reported to have good diagnostic accuracy. However, most of these studies have been single-center trials based on each institutional classification, and worldwide multicenter trials aimed at their standardization are needed to validate the clinical benefits of the various NBI classification systems.
Department of Endoscopy, Jikei University School of Medicine, 3-25-8, Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan. aihara@jikei.ac.jp
Hiroyuki
H
Aihara
Shoichi
S
Saito
Hisao
H
Tajiri
D018256:Adenomatous Polyps / Q000473:pathology; D002196:Capillaries / Q000473:pathology*; D003106:Colon / Q000098:blood supply / Q000473:pathology*; D003111:Colonic Polyps / Q000473:pathology; D003113:Colonoscopy / Q000379:methods*; D015179:Colorectal Neoplasms / Q000473:pathology*; D055088:Early Detection of Cancer / Q000379:methods*; D006801:Humans; D007413:Intestinal Mucosa / Q000098:blood supply / Q000473:pathology*; D062048:Narrow Band Imaging