Luminescent rhenium fac-tricarbonyl-containing complexes of androgenic oxo-steroids.
A new route to luminescent derivatives of androgenic steroids containing a ketone group in the 3- or 17-position has been developed. Reaction with the fac-Re(CO)(3)Cl complex of 3,3'-diamino-2,2'-bipyridine (complex 1) afforded a cyclic aminal product with different steroids. The rate of reaction and yield varies according to the conjugation or steric hindrance around the ketone group.
Department of Chemical & Biological Sciences, University of Huddersfield, Queensgate, Huddersfield, West Yorks, UK.
Sam
S
Bullock
Andrew J
AJ
Hallett
Lindsay P
LP
Harding
Joshua J
JJ
Higginson
Sean A F
SA
Piela
Simon J A
SJ
Pope
Craig R
CR
Rice
D015082:2,2'-Dipyridyl / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003959:Diamines / Q000138:chemical synthesis / Q000737:chemistry; D007659:Ketones / Q000737:chemistry; D008968:Molecular Conformation; D011789:Quantum Theory; D012211:Rhenium / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D013256:Steroids / Q000737:chemistry*
C579830:3,3'-diamino-2,2'-bipyridine; D056831:Coordination Complexes; D003959:Diamines; D007659:Ketones; D013256:Steroids; D015082:2,2'-Dipyridyl; D012211:Rhenium