Analysis of the VP2 protein gene of canine parvovirus strains from affected dogs in Japan.
To clarify the evolution of canine parvovirus 2 (CPV-2) that has recently been epidemic in Japan, VP2 gene sequences at positions 3556-4166 were analyzed in 107 CPV-2 strains obtained from rectal swabs of diarrheic dogs from 2009 to 2011. CPV-2b (95 strains) was more frequently detected than CPV-2a (nine strains), while CPV-2c was not detected. Remaining three strains were identified as the original type CPV-2, which should be derived from vaccines. These findings are similar to the previous results involving Japanese strains, suggesting there has been no great change in the recent CPV-2 epidemic in Japan. This epidemic is the same as that in Taiwan. Furthermore, a 324-lle mutant, which has been reported in Korean and Chinese strains, was detected in 66.7% of CPV-2a strains.
Veterinary Diagnostic Laboratory, Marupi Lifetech Co. Ltd, 103 Fushiocho, Ikeda, Osaka 563-0011, Japan. takehisa-soma@ds-pharma.co.jp
Takehisa
T
Soma
Satoshi
S
Taharaguchi
Tsuyoshi
T
Ohinata
Hiroshi
H
Ishii
Motonobu
M
Hara
D019943:Amino Acid Substitution; D000818:Animals; D036022:Capsid Proteins / Q000235:genetics / Q000378:metabolism*; D004283:Dog Diseases / Q000453:epidemiology / Q000821:virology*; D004285:Dogs; D015967:Gene Expression Regulation, Viral; D007564:Japan / Q000453:epidemiology; D010322:Parvoviridae Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D017993:Parvovirus, Canine / Q000235:genetics / Q000378:metabolism*
D036022:Capsid Proteins