Balance impairment, physical ability, and its link with disease severity in patients with intermittent claudication.
BACKGROUND
To determine whether increasing claudication severity is associated with impaired balance and physical functional ability.


METHODS
A prospective observational study in claudicants was performed. Disease severity was determined according to Rutherford's criteria. Patient's balance was assessed objectively using computerized dynamic posturography (CDP-Sensory Organization Test [SOT]; NeuroCom). "Bedside" assessment of balance was performed using the Timed Up and Go (TUG) test (dynamic balance) and the Full Tandem Stance test (static balance). Physical function was assessed using the Summary Physical Performance Battery (SPPB) score.


RESULTS
185 claudicants were assessed (median age of 69 [IQR 63-74] years; 137 [74.1%] men). Fourteen claudicants were classified as Rutherford grade 0, 26 as grade I, 76 as grade II, and 69 as grade III. All Rutherford groups were comparable for age, gender, BMI, and comorbidities. Increasing Rutherford grade was associated with a significant deterioration in objective balance as determined by a failed SOT test: 3 (21.4%) in grade 0; 9 (34.6%) in grade I; 39 (52.7%) in grade II; and 41 (59.4%) in grade III (chi-squared 9.693, df 3, P = 0.021). A significant difference was also found with dynamic balance (TUG test), but not static balance (full tandem stance). Increasing claudication severity was also associated with significantly worse physical function: SPPB score.


CONCLUSIONS
Specific objective tests demonstrate impaired balance and physical function are common in claudicants and become more frequent with increasing severity of claudication. Simple "bedside" measures may be sufficiently sensitive to detect this.
Academic Vascular Surgical Unit, Hull Royal Infirmary, Hull, Hull York Medical School, University of Hull, Hull, UK. risha@doctors.net.uk
Risha A
RA
Gohil
Katherine A
KA
Mockford
Fayyaz
F
Mazari
Junaid
J
Khan
Natalie
N
Vanicek
Ian C
IC
Chetter
Patrick A
PA
Coughlin
D000058:Accidental Falls / Q000517:prevention & control; D000368:Aged; D016009:Chi-Square Distribution; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D007383:Intermittent Claudication / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010808:Physical Examination; D004856:Postural Balance; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012678:Sensation Disorders / Q000209:etiology* / Q000503:physiopathology; D012720:Severity of Illness Index