The effect of preoperative antimicrobial administration on culture results in dogs undergoing cystotomy.
OBJECTIVE
To evaluate the effect of preoperative antimicrobial administration on culture results in dogs undergoing cystotomy as a treatment for urolithiasis.


METHODS
Prospective controlled study. Animals-41 dogs undergoing cystotomy for cystic calculi removal.


METHODS
Urine samples were collected at time of anesthetic induction and during surgery prior to cystotomy, and a mucosal biopsy and culturette swab was collected during surgery from a control group, which received antimicrobials only after surgical culture sample collection, and from an experimental group, which received antimicrobials at the time of anesthetic induction.


RESULTS
17 of 41 patients had positive culture results at anesthetic induction. Twenty of 41 patients had positive results of cultures for the surgical sample. No dogs that had positive results before antimicrobial administration had negative results after antimicrobial administration. There were no significant changes to urinalysis results regardless of group. Calcium monohydrate uroliths were the most common stone removed (24/41), followed by magnesium ammonium phosphate uroliths (11/41).


CONCLUSIONS
There was no difference in culture results (positivity and bacterial type) when antimicrobials were given at anesthetic induction versus after surgical culture sample collection for dogs undergoing cystotomy for cystic calculi removal.
Animal Medical Center, 510 E 62nd St, New York, NY 10065, USA. njbuote@aol.com
Nicole J
NJ
Buote
Janet R
JR
Kovak-McClaran
Andrew S
AS
Loar
Karen L
KL
Cherrone
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D053715:Cystotomy / Q000662:veterinary*; D004283:Dog Diseases / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery*; D004285:Dogs; D005260:Female; D008297:Male; D009092:Mucous Membrane / Q000382:microbiology; D011300:Preoperative Care; D001744:Urinary Bladder Calculi / Q000382:microbiology / Q000601:surgery / Q000662:veterinary*; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*
D000900:Anti-Bacterial Agents