A case report: a young waiter with Paget-Schroetter syndrome.
BACKGROUND
Paget-Schroetter syndrome (PSS) is a rare presentation of primary axillary subclavian vein thrombosis that classically occurs in young men with a degree of underlying thoracic outlet syndrome after a period of upper extremity exertion. The primary complication of PSS is post-thrombotic syndrome, a result of chronic venous hypertension.


OBJECTIVE
To educate Emergency Physicians on this condition to potentiate timely diagnosis and appropriate disposition.


METHODS
A 29-year-old right-handed restaurant waiter presented with 3 days of non-painful, gradual-onset right upper extremity swelling with normal vital signs. The patient's history was otherwise notable for subjective fevers and a right forearm abrasion. Upon examination, the right upper extremity was neurovascularly intact and remarkable for uniform edema and erythema extending distally from the level of the mid-humerus. The primary differential diagnoses were deep venous thrombosis (DVT) vs. soft tissue infection. Venous phase contrast computed tomography did not reveal evidence of underlying soft tissue infection and was inconclusive regarding a DVT. Ultrasound demonstrated a right subclavian vein DVT. The patient was admitted and underwent thrombolysis, venolysis, and first rib resection and initiation of warfarin.


CONCLUSIONS
PSS is a rare presentation of upper-extremity DVT occurring classically in patients without commonly recognized pro-thrombotic risk factors. PSS carries the potential of significant morbidity in the form of post-thrombotic syndrome and pulmonary embolism. Current literature suggests that optimal outcomes are achieved when treatment is initiated within 6 weeks of onset. The treatment paradigm calls for thrombolysis and, frequently, a first rib resection.
Department of Emergency Medicine, Harbor-UCLA Medical Center, Torrance, California, USA.
Nicholas
N
Drakos
Marianne
M
Gausche-Hill
D000328:Adult; D016121:Brachiocephalic Veins / Q000000981:diagnostic imaging; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006801:Humans; D008297:Male; D009784:Occupational Diseases / Q000175:diagnosis* / Q000628:therapy; D015642:Radiology, Interventional; D012147:Restaurants; D018461:Soft Tissue Infections / Q000175:diagnosis; D013350:Subclavian Vein / Q000000981:diagnostic imaging; D017131:Thrombectomy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage; D018616:Ultrasonography, Doppler, Duplex; D056824:Upper Extremity Deep Vein Thrombosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy
D005343:Fibrinolytic Agents; D010959:Tissue Plasminogen Activator