Spinal cord compression: an unusual presentation of malignant pleural mesothelioma. A case report and review of the literature.
Pleural malignant mesothelioma is a locally invasive tumor that tends to progress due to direct extension of the tumor into the pulmonary parenchyma, the chest wall, the mediastinum, or the abdominal cavity via the diaphragm. In the later stages of the disease, distant metastases can occur. Metastases to the nervous system are rare, and clinical signs of nervous system involvement typically appear between 2 months and 6 years after the primary diagnosis. However, the case presented here manifested as neurological impairment without any respiratory symptoms.
Clinica del Lavoro Luigi Devoto, Department of Preventive Medicine, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy. carolina.mensi@unimi.it
Carolina
C
Mensi
Lorenzo
L
Termine
Anna
A
Garberi
Stefano
S
Meroni
Daniel
D
Levi
Luca
L
Balzarini
Luciano
L
Riboldi
D000368:Aged; D001194:Asbestos / Q000633:toxicity*; D001416:Back Pain / Q000209:etiology; D002273:Carcinogens / Q000633:toxicity*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D007866:Leg; D008279:Magnetic Resonance Imaging; D008297:Male; D008654:Mesothelioma / Q000139:chemically induced / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D018908:Muscle Weakness / Q000209:etiology; D016273:Occupational Exposure / Q000009:adverse effects*; D010166:Palliative Care / Q000379:methods; D010243:Paralysis / Q000209:etiology; D010997:Pleural Neoplasms / Q000139:chemically induced / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D013117:Spinal Cord Compression / Q000150:complications / Q000209:etiology*; D013904:Thoracic Vertebrae; D014057:Tomography, X-Ray Computed
D002273:Carcinogens; D001194:Asbestos