Advances in molecular imaging of atherosclerosis and myocardial infarction: shedding new light on in vivo cardiovascular biology.
Molecular imaging of the cardiovascular system heavily relies on the development of new imaging probes and technologies to facilitate visualization of biological processes underlying or preceding disease. Molecular imaging is a highly active research discipline that has seen tremendous growth over the past decade. It has broadened our understanding of oncologic, neurologic, and cardiovascular diseases by providing new insights into the in vivo biology of disease progression and therapeutic interventions. As it allows for the longitudinal evaluation of biological processes, it is ideally suited for monitoring treatment response. In this review, we will concentrate on the major accomplishments and advances in the field of molecular imaging of atherosclerosis and myocardial infarction with a special focus on magnetic resonance imaging.
Division of Imaging Science and Biomedical Engineering, King's College London, United Kingdom. alkystis.1.phinikaridou@kcl.ac.uk
Alkystis
A
Phinikaridou
Marcelo E
ME
Andia
Ajay M
AM
Shah
René M
RM
Botnar
D000818:Animals; D017209:Apoptosis; D050197:Atherosclerosis / Q000000981:diagnostic imaging / Q000473:pathology*; D004195:Disease Models, Animal; D006801:Humans; D008279:Magnetic Resonance Imaging; D057054:Molecular Imaging / Q000379:methods* / Q000639:trends*; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000473:pathology*; D009336:Necrosis; D049268:Positron-Emission Tomography; D015899:Tomography, Emission-Computed, Single-Photon