Diagnosis of celiac disease.
This article reviews issues related to identifying the appropriate patient to test for celiac disease, the performance characteristics of serologic testing, the role of gene testing for human leukocyte antigen DQ2 and DQ8 haplotypes, and issues related to the performance of small intestinal biopsy. The article concludes with a review of special diagnostic considerations in pediatric patients.
Department of Medicine, Mailman School of Public Health, Celiac Disease Center, Columbia University, New York, NY 10032, USA. bl114@columbia.edu
Benjamin
B
Lebwohl
Alberto
A
Rubio-Tapia
Asaad
A
Assiri
Catherine
C
Newland
Stefano
S
Guandalini
D000906:Antibodies / Q000097:blood; D001323:Autoantibodies / Q000097:blood; D001706:Biopsy; D002446:Celiac Disease / Q000175:diagnosis*; D016145:Endoscopy, Digestive System; D005820:Genetic Testing; D006683:HLA-DQ Antigens / Q000235:genetics; D006801:Humans; D007421:Intestine, Small / Q000473:pathology; D008403:Mass Screening
D000906:Antibodies; D001323:Autoantibodies; D006683:HLA-DQ Antigens