Treatment of Stargardt disease with dobesilate.
Stargardt disease is a common inherited macular degeneration characterised by a significant loss in the central vision during the first or second decade of the life. Bilateral atrophic changes in the central retina are associated with degeneration of photoreceptors and underlying retinal pigment epithelium, and yellow flecks are extending from the macula. We present a patient with Stargardt disease treated with an intravitreal injection of dobesilate, showing an improvement of visual acuity 4 weeks after treatment.
Departamento de Investigación, IRYCIS, Hospital Universitario Ramón y Cajal, Madrid, Spain. pedro.cuevas@hrc.es
Pedro
P
Cuevas
Luis A
LA
Outeiriño
Javier
J
Angulo
Guillermo
G
Giménez-Gallego
D000328:Adult; D002123:Calcium Dobesilate / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005346:Fibroblast Growth Factors / Q000037:antagonists & inhibitors*; D006490:Hemostatics / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D058449:Intravitreal Injections; D008268:Macular Degeneration / Q000151:congenital* / Q000188:drug therapy; D000080362:Stargardt Disease
D006490:Hemostatics; D002123:Calcium Dobesilate; D005346:Fibroblast Growth Factors