Synthesis and properties of squaraine-modified DNA.
The incorporation of squaraines into DNA via the phosphoramidite approach is described. High molar absorptivity, environment-sensitive fluorescence properties and intense CD effects render squaraines valuable building blocks for DNA-based optical probes and nanostructures.
Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland.
Larysa I
LI
Markova
Vladimir L
VL
Malinovskii
Leonid D
LD
Patsenker
Robert
R
Häner
D060326:Chemistry Techniques, Synthetic; D003503:Cyclobutanes / Q000737:chemistry*; D004247:DNA / Q000138:chemical synthesis* / Q000737:chemistry*; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis / Q000737:chemistry; D055620:Optical Phenomena; D009943:Organophosphorus Compounds / Q000737:chemistry; D010636:Phenols / Q000737:chemistry*; D013057:Spectrum Analysis
D003503:Cyclobutanes; D009838:Oligodeoxyribonucleotides; D009943:Organophosphorus Compounds; D010636:Phenols; C434331:phosphoramidite; C480596:squaraine; D004247:DNA