Metal-on-metal hips: cobalt can induce an endotoxin-like response.
Alison Jane
AJ
Tyson-Capper
Helen
H
Lawrence
James P
JP
Holland
David J
DJ
Deehan
John A
JA
Kirby
D000469:Alkaline Phosphatase / Q000096:biosynthesis*; D000818:Animals; D002460:Cell Line; D003035:Cobalt / Q000009:adverse effects*; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D051379:Mice; D051197:Toll-Like Receptor 4 / Q000378:metabolism*
C495345:TLR4 protein, human; D051197:Toll-Like Receptor 4; D003035:Cobalt; D000469:Alkaline Phosphatase