Unexpected C-C bond cleavage: a route to 3,6-diarylpyridazines and 6-arylpyridazin-3-ones from 1,3-dicarbonyl compounds and methyl ketones.
An unexpected C-C bond cleavage has been revealed in the absence of metal. This observation has been exploited to develop an efficient approach toward 3,6-diarylpyridazines and 6-arylpyridazin-3-ones from simple and commercially available 1,3-dicarbonyl compounds and methyl ketones.
Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, PR China.
Qinghe
Q
Gao
Yanping
Y
Zhu
Mi
M
Lian
Meicai
M
Liu
Jingjing
J
Yuan
Guodong
G
Yin
Anxin
A
Wu
D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D011724:Pyridazines / Q000737:chemistry*
D007659:Ketones; D011724:Pyridazines