Necrotizing periodontitis as a possible manifestation of common variable immunodeficiency.
Common variable immunodeficiency (CVID) is an inherited disease characterized by hypogammaglobulinaemia and impaired humoural immunoresponse and is mainly associated with recurrent infections of the airway and the digestive tract. An 18-year old female with a diagnosis of CVID associated with a devastating necrotizing periodontitis, ultimately resulting in complete destruction of the periodontium and loss of all teeth, is reported. Clinical, biochemical, microbiological and radiographic examinations are presented. The report highlights the likely importance of immunoglobulin replacement and intensive dental hygiene in CVID patients, and the devastating effect of non-compliance in such patients.
Department of Cranio-, Maxillofacial and Oral Surgery, Medical University of Innsbruck, Innsbruck, Austria. daniel.dalla-torre@uki.at
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Dalla Torre
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Burtscher
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Jank
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Kloss
D000293:Adolescent; D017074:Common Variable Immunodeficiency / Q000150:complications*; D005260:Female; D006801:Humans; D010518:Periodontitis / Q000150:complications* / Q000000981:diagnostic imaging; D011862:Radiography, Panoramic