Depression with psychotic features in a child with SLE: successful therapy with psychotropic medications--case report.
Systemic lupus erythematosus (SLE) is a multisystemic, autoimmune disease of unknown etiology, which affects multiple organ systems, including the central nervous system (CNS). Neuropsychiatric manifestations are seen in 13-75% of all SLE patients, with equal frequency in children and adults. Despite a high prevalence of psychiatric manifestations, there is no consensus on the proper treatment of such cases. We report here a case of an 11-year-old girl diagnosed with a severe depressive episode with psychotic features, treated successfully with risperidone and sertraline as an adjunct to immunosuppressive therapy.
Institute of Mental Health, Belgrade, Serbia and Montenegro.
Milica Pejovic
MP
Milovancevic
Vladimir
V
Miletic
Smiljka Popovic
SP
Deusic
Saveta Draganic
SD
Gajic
Dusica Lecic
DL
Tosevski
D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002648:Child; D003863:Depression / Q000150:complications* / Q000188:drug therapy / Q000523:psychology; D003975:Diazepam / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000523:psychology; D011618:Psychotic Disorders / Q000150:complications* / Q000188:drug therapy / Q000523:psychology; D018967:Risperidone / Q000627:therapeutic use*; D016896:Treatment Outcome
D014151:Anti-Anxiety Agents; D014150:Antipsychotic Agents; D018967:Risperidone; D003975:Diazepam