Seroprevalence of Chlamydophila pneumoniae in HIV-infected children in Vietnam.
A total of 89 blood samples collected from HIV-infected infants and children from provinces of southern Vietnam who were hospitalized at Children's Hospital 1, Ho Chi Minh City, during the 1-year period from October 2004 to September 2005 were submitted to serological screening for IgG, IgA, and IgM antibodies against Chlamydophila pneumoniae (C. pneumoniae). The presence of this microorganism was also evaluated by PCR. The results showed that 64 % of the samples were positive for anti-C. pneumoniae IgG, 31.5 % were positive for IgA, and 3.4 % were positive for IgM. The highest prevalences of IgG and IgA positivity, 75 % and 66.7 %, respectively, were noted in the 1- to 2-year-old age group. However, all the samples were negative for C. pneumoniae by PCR. The study revealed a high seroprevalence of C. pneumoniae in Vietnamese infants and children with HIV/AIDS.
Division of Microbiology, Department of Pathology and Microbiology, Nihon University School of Medicine, 30-1 Ohyaguchi Kamimachi, Itabashi-ku, Tokyo, 173-8610, Japan. quangsj@med.nihon-u.ac.jp
Quang Duy
QD
Trinh
Ngan Thi Kim
NT
Pham
Nhut Tin
NT
Le Nguyen
Bao Quoc
BQ
Lam
Kim Thoa
KT
Le Phan
Khanh Huu
KH
Truong
Thinh Quoc
TQ
Le
Hung Thanh
HT
Nguyen
Thuong Chi
TC
Tang
Yasuyuki
Y
Izumi
Shihoko
S
Komine-Aizawa
Hiroshi
H
Ushijima
Satoshi
S
Hayakawa
D000907:Antibodies, Bacterial / Q000097:blood; D002675:Child, Preschool; D023521:Chlamydophila Infections / Q000453:epidemiology* / Q000276:immunology / Q000821:virology*; D016993:Chlamydophila pneumoniae / Q000302:isolation & purification*; D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D016036:Seroepidemiologic Studies; D014744:Vietnam
D000907:Antibodies, Bacterial