Evaluation of centrifuged bone marrow on bone regeneration around implants in rabbit tibia.
OBJECTIVE
To evaluate the bone regeneration of cervical defects produced around titanium implants filled with blood clot and filled with centrifuged bone marrow (CBM) by means of histomorphometric analysis.


METHODS
Twelve rabbits received 2 titanium implants in each right tibia, with the upper cortical prepared with a 5-mm drill and the lower cortex with a 3-mm-diameter drill. Euthanasia was performed to allow analysis at 7, 21, and 60 days after operation. The samples were embedded in light curing resin, cut and stained with alizarin red and Stevenel blue for a histomorphometric analysis of the bone-to-implant contact (BIC) and the bone area around implant (BA). The values obtained were statistically analyzed using the nonparametric Kruskal-Wallis test (P = 0.05).


RESULTS
At 60 days postoperation, the groups had their cervical defects completely filled by neoformed bone tissue. There was no statistically significant difference between the groups regarding BIC and BA during the analyzed periods.


CONCLUSIONS
There was no difference in the bone repair of periimplant cervical defects with or without the use of CBM.
Discipline of Surgery, Department of Surgery, University of Cuiabá, Cuiabá, Brazil.
Walter
W
Betoni
Thallita P
TP
Queiroz
Eloá R
ER
Luvizuto
Rodolpho
R
Valentini-Neto
Idelmo R
IR
Garcia-Júnior
Pedro F E
PF
Bernabé
D000818:Animals; D000880:Anthraquinones; D001769:Blood; D016026:Bone Marrow Transplantation; D001861:Bone Regeneration / Q000502:physiology*; D016723:Bone Remodeling / Q000502:physiology; D002498:Centrifugation; D004396:Coloring Agents; D003238:Connective Tissue / Q000473:pathology; D003758:Dental Implantation, Endosseous / Q000295:instrumentation; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry; D017267:Dental Prosthesis Design; D008297:Male; D016348:Osseointegration / Q000502:physiology; D010012:Osteogenesis / Q000502:physiology; D011817:Rabbits; D013499:Surface Properties; D013977:Tibia / Q000473:pathology / Q000601:surgery*; D013997:Time Factors; D014025:Titanium / Q000737:chemistry
D000880:Anthraquinones; D004396:Coloring Agents; D015921:Dental Implants; D003764:Dental Materials; C010078:alizarin; D014025:Titanium