[Acute oxygen desaturation following peritonectomy and hyperthermic intraperitoneal chemotherapy].
Intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) may have a significant impact on physiological functions and is therefore a special challenge for anesthetists. In the presented case  after opening the parietal pleura during subphrenical peritonectomy the HIPEC solution accidentally leaked into the right hemithorax with subsequent pleural effusion of more than 2,000 ml. After extubation the patient presented with acute oxygen desaturation and orthopnea. Following pleural sonography and chest X-ray in the operating theatre and recovery area, a thorax drainage was inserted into the pleural space and ventilation support was provided by non-invasive continuous positive air pressure (CPAP) ventilation. With reference  to recent publications the anesthesiological management of patients undergoing HIPEC is presented.
Anästhesiologische Universitätsklinik, Universitätsklinikum Freiburg, Freiburg, Deutschland.
C-N
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Schlürmann
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R
Schmidt
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Kalbhenn
D000328:Adult; D060666:Airway Extubation; D000758:Anesthesia / Q000379:methods; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001784:Blood Gas Analysis; D003131:Combined Modality Therapy; D045422:Continuous Positive Airway Pressure; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D000860:Hypoxia / Q000209:etiology* / Q000628:therapy*; D007044:Hysterectomy; D017567:Karnofsky Performance Status; D010051:Ovarian Neoplasms / Q000473:pathology; D010534:Peritoneal Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000628:therapy*; D010537:Peritoneum / Q000601:surgery*; D011030:Pneumothorax / Q000628:therapy; D018467:Positive-Pressure Respiration, Intrinsic; D011183:Postoperative Complications / Q000628:therapy*
D000970:Antineoplastic Agents