Serum uric acid: marker for atherosclerosis as it is positively associated with "atherogenic index of plasma".
BACKGROUND
Serum uric acid (SUA) has been known to be associated with cardiovascular diseases. "Atherogenic index of plasma" (AIP) is considered a very sensitive predictor of future cardiovascular events.


OBJECTIVE
This study was conducted to analyse the association of AIP with SUA and various other lipid parameters.


METHODS
Parameters were measured on a fully automated analyser using standard reagent kits in a retrospective study involving 248 male Indian subjects between 40 to 59 years of age.


RESULTS
AIP correlates: moderately with TC/HDL-C (r = 0.47, p < 0.0001); to a lesser extent but comparably (r = 0.2, p < 0.01) with SUA, LDL-C/HDL-C and TC; negligibly with LDL-C and age.


CONCLUSIONS
As SUA is positively associated with AIP it can be used as a supplementary marker for atherosclerosis/CVD in upper-middle-aged men.
Department of Biochemistry, SRMS Institute of Medical Sciences, Bareilly, UP, India. simantbaliarsingh@gmail.com
Simant
S
Baliarsingh
Neha
N
Sharma
Ranadip
R
Mukherjee
D000328:Adult; D050197:Atherosclerosis / Q000473:pathology*; D015415:Biomarkers / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood*; D050171:Dyslipidemias / Q000473:pathology*; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged; D011933:Reagent Kits, Diagnostic; D012189:Retrospective Studies; D012307:Risk Factors; D014527:Uric Acid / Q000097:blood*
D015415:Biomarkers; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D011933:Reagent Kits, Diagnostic; D014527:Uric Acid