Dietary patterns, goitrogenic food, and thyroid cancer: a case-control study in French Polynesia.
French Polynesia has one of the world's highest thyroid cancer incidence rates. A case-control study among native residents of French Polynesia included 229 cases of differentiated thyroid cancer diagnosed between 1979 and 2004, and 371 population controls. Dietary patterns and goitrogenic food consumption (cabbage, cassava) were analyzed. We used a factor analysis to identify dietary patterns and a conditional logistic regression analysis to investigate the association between dietary patterns or food items and thyroid cancer risk. Two distinct dietary patterns were identified: traditional Polynesian and Western. A nonsignificant inverse association was observed between the traditional Polynesian dietary pattern and thyroid cancer risk. The Western pattern was not associated with thyroid cancer risk. Cassava consumption was significantly associated with a decreased risk of thyroid cancer. In conclusion, a traditional Polynesian dietary pattern led to a weak reduced risk of thyroid cancer in French Polynesia. The protective effect of cassava on this cancer does not seem to be substantially different from that of cabbage, which was the main goitrogenic food studied to date.
Radiation Epidemiology Group, CESP Centre for research in Epidemiology and Population Health, U1018 INSERM, Villejuif, France.
Énora
É
Cléro
Françoise
F
Doyon
Vaïana
V
Chungue
Frédérique
F
Rachédi
Jean-Louis
JL
Boissin
Joseph
J
Sebbag
Larrys
L
Shan
Carole
C
Rubino
Florent
F
de Vathaire
D000293:Adolescent; D000328:Adult; D013956:Antithyroid Agents / Q000008:administration & dosage*; D001937:Brassica; D016022:Case-Control Studies; D002648:Child; D005247:Feeding Behavior; D005260:Female; D005500:Follow-Up Studies; D005502:Food; D005638:Fruit; D006801:Humans; D016015:Logistic Models; D002365:Manihot; D008875:Middle Aged; D011114:Polynesia / Q000453:epidemiology; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013964:Thyroid Neoplasms / Q000453:epidemiology*; D014675:Vegetables; D055815:Young Adult
D013956:Antithyroid Agents