[Case of cerebellar hemorrhage complicated with Takotsubo cardiomyopathy - usefulness of plasma brain natriutetic peptide measurement for the diagnosis].
A 94-year-old woman was admitted to our hospital because of altered mental status and cerebellar ataxia of left upper and lower extremities. A brain CT scan revealed a right cerebellar hemorrhage approximately 15 cc. Plasma brain natriuretic peptide (BNP) value on admission was 1,064.6 pg/ml. Twelve-lead ECG revealed negative T-wave in V3-V5. Transthoracic echocardiology confirmed an ejection fraction of 35%, and left ventricular apical akinesia and basal hyperkinesis were seen. Plasma BNP value was dramatically declined in the subacute phase of cerebellar hemorrhage. On the 14th day, echocardiography showed completely improvement of the left ventricular wall abnormalities. Therefore, we diagnosed having as a Tako-tsubo cardiomyopathy. Tako-tsubo cardiomyopathy is a rare complication of acute intracerebral hemorrhage. In the present case, plasma BNP was effective as a screening marker of Tako-tsubo cardiomyopathy and serial measurement of BNP was made helpful to know cardiac status.
Department of Stroke Medicine, Kawasaki Medical School.
Takashi
T
Shiromoto
Kensaku
K
Shibazaki
Kazumi
K
Kimura
Kenichiro
K
Sakai
D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D002543:Cerebral Hemorrhage / Q000150:complications* / Q000175:diagnosis; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006801:Humans; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D054549:Takotsubo Cardiomyopathy / Q000175:diagnosis* / Q000209:etiology*; D014057:Tomography, X-Ray Computed
D015415:Biomarkers; D020097:Natriuretic Peptide, Brain