Assembly of heterogeneous functional nanomaterials on DNA origami scaffolds.
One on each side: gold nanoparticles (AuNPs) and semiconducting quantum dots (QDs) are integrated on a single DNA origami scaffold. Streptavidin-functionalized QDs bind to biotin anchors on one side of the DNA origami, while DNA-coated AuNPs bind through DNA hybridization to single-stranded DNA on the other side of the scaffold. This approach offers a new path toward the organization of complex systems consisting of disparate materials.
Department of Applied Physics & Applied Mathematics, Columbia University, New York, NY 10027, USA. rw2399@columbia.edu
Risheng
R
Wang
Colin
C
Nuckolls
Shalom J
SJ
Wind
D004247:DNA / Q000737:chemistry* / Q000648:ultrastructure; D053768:Metal Nanoparticles / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D045663:Quantum Dots
D004247:DNA