Brønsted acid-assisted intramolecular aminohydroxylation of N-alkenylsulfonamides under heavy metal-free conditions.
The intramolecular aminohydroxylation of N-alkenylsulfonamides proceeded under heavy metal-free conditions to give substituted prolinol derivatives in high yields. Oxone activated by catalytic Brønsted acid worked well as an electrophilic oxidant for this reaction.
Department of Chemistry, Graduate School of Science, Chiba University, Yayoi-cho 1-33, Inage-ku, Chiba 263-8522, Japan. moriyama@faculty.chiba-u.jp
Katsuhiko
K
Moriyama
Yuta
Y
Izumisawa
Hideo
H
Togo
D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D019216:Metals, Heavy / Q000737:chemistry*; D015394:Molecular Structure; D016877:Oxidants / Q000737:chemistry*; D011759:Pyrrolidines / Q000737:chemistry*; D013237:Stereoisomerism; D013449:Sulfonamides / Q000737:chemistry*
D000475:Alkenes; D019216:Metals, Heavy; D016877:Oxidants; D011759:Pyrrolidines; D013449:Sulfonamides; C010509:prolinol