[The signaling systems in Echinococcus multilocularis].
Signaling pathway is the way by which cells receive various stimulation signals, and produce a series of corresponding responses, such as cell proliferation, differentiation and apoptosis. During infection with Echinococcus multilocularis, both parasite and host cells may secrete many cytokines such as insulin, which make stimulating signals transmitted into the cells through their receptors on the surface of cells. As a result, the parasite can grow and proliferate in the host. Study on related signaling pathways and their blocking drugs will play a crucial role in the control of alveolar echinococcosis caused by the larvae of E. multilocularis.
State Key Laboratory of Veterinary Etiological Biology/Key Laboratory of Veterinary Parasitology of Gansu Province/Key Laboratory of Zoonoses of Agriculture Ministry/Lanzhou Veterinary Research Institute, CAAS, Lanzhou 730046, China.
Xing-Wei
XW
Ni
Hong-Bin
HB
Yan
Zhong-Zi
ZZ
Lou
Wan-Zhong
WZ
Jia
D000818:Animals; D016207:Cytokines / Q000378:metabolism; D048210:Echinococcus multilocularis / Q000378:metabolism*; D015398:Signal Transduction
D016207:Cytokines