[Information capability of the test with radioadaptive response in functiional evaluation of pilots].
Information capability of the radioadaptive response test was assessed during functional evaluation of pilots in the course of adaptation to fight factors. Functional evaluation was made on the system level, i.e., by cardiorespiratory parameters (spirometry and arteriorcardiography), the cellular level by individual sensitivity to ionized radiatiin of metabolic shifts (laser correlation spectroscopy of biological liquids). Changes in molecular composition of blood serum and cardiorespiratory functions were compared with individual radiosensitivity of pilots with varying fight time. Incidence of and strength of lymphocytes' RAR decreased with increasing flight hours. In light scattering spectra the input of particles with small hydrodynamic radius (no more than 11 nm) reduced and that of large particles (more than 200 nm) increased. Total power of the cardiac rhythm variability (CRV) spectrum decreased whereas stress-index grew in value. Breathing test raised peripheral systolic and diastolic blood pressure in masked pilots w/o RAR. Besides, it reduced total spectrum of systolic pressure variability and input of very low frequencies. In the group of RAR pilots, relative input of low frequencies into CRV grew and of high frequencies decreased; blood pressure did not alter Decreased input of small particles and increased input of large particles in light scattering as compared with baseline values were found only in RAR pilots suggesting shifts in metabolism and humoral immunity. It can be hypothesized that level of individual radiosensitivity reflects general resistance of organism to negative factors of environment.
I B
IB
Alchinova
N N
NN
Khlebnikova
M Iu
MIu
Karganov
D000222:Adaptation, Physiological; D000328:Adult; D001794:Blood Pressure; D002478:Cells, Cultured; D002869:Chromosome Aberrations / Q000528:radiation effects*; D004562:Electrocardiography; D005720:Gamma Rays; D006339:Heart Rate; D006801:Humans; D056724:Immunity, Humoral; D007621:Karyotyping; D054018:Lasers, Excimer; D007963:Leukocytes, Mononuclear / Q000528:radiation effects*; D008213:Lymphocyte Activation; D008297:Male; D008938:Mitosis / Q000235:genetics / Q000528:radiation effects*; D013026:Space Flight; D013057:Spectrum Analysis; D013147:Spirometry; D013997:Time Factors; D055815:Young Adult