In vitro antibacterial activity of different self-etch adhesives.
OBJECTIVE
The aim of this study was to evaluate and compare the antimicrobial activity of different self-etch adhesives by means of the agar disc diffusion test.


METHODS
Streptococcus salivarius, Streptococcus sanguis and Streptococcus mutans strains were selected to evaluate the antimicrobial activity of various self-etch adhesives (Futurabond NR, G-aenial Bond, Adper™ Easy Bond Self-Etch Adhesive, Clearfil Protect Bond, One Coat 7.0, Clearfil S3 Bond, Clearfil SE Bond) using the agar disc diffusion test; 0.2% Chlorexidine digluconate was used as control. Paper disks were saturated with 10 µL of each adhesive system and placed onto culture agar plates pre-adsorbed with bacterial cells and further incubated for 24 h at 37°C. The growth inhibition zones around each adhesive were recorded and compared for each bacterial strain.


RESULTS
The test results of the various self-etch adhesives were significantly different.


CONCLUSIONS
The results of the present investigation showed that the addition of MDPB monomer to an adhesive system enhances its antibacterial effect against S. salivarius, S. sanguis and S. mutans.
Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, School of Dentistry, University of Pavia, Pavia, Italy. claudio.poggio@unipv.it
Claudio
C
Poggio
Carla Renata
CR
Arciola
Sergey
S
Cepurnykh
Marco
M
Chiesa
Andrea
A
Scribante
Laura
L
Selan
Marcello
M
Imbriani
Livia
L
Visai
D000134:Acid Etching, Dental / Q000379:methods*; D000180:Acrylic Resins / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D017438:Bisphenol A-Glycidyl Methacrylate / Q000494:pharmacology; D002710:Chlorhexidine / Q000031:analogs & derivatives / Q000494:pharmacology; D017220:Dentin-Bonding Agents / Q000494:pharmacology*; D052978:Disk Diffusion Antimicrobial Tests; D008689:Methacrylates / Q000494:pharmacology; D010755:Organophosphates / Q000494:pharmacology; D011726:Pyridinium Compounds / Q000494:pharmacology; D019279:Resin Cements / Q000494:pharmacology; D013291:Streptococcus / Q000187:drug effects* / Q000254:growth & development; D013295:Streptococcus mutans / Q000187:drug effects / Q000254:growth & development; D013298:Streptococcus sanguis / Q000187:drug effects / Q000254:growth & development; D013997:Time Factors
D000180:Acrylic Resins; C489662:AdheSE cement; C489661:Adper Prompt Self-Etch; D000900:Anti-Bacterial Agents; C503075:Clearfil Protect Bond; C438313:Clearfil SE Bond; D017220:Dentin-Bonding Agents; D008689:Methacrylates; C426984:One Coat Bond; D010755:Organophosphates; D011726:Pyridinium Compounds; D019279:Resin Cements; C512545:futurabond NR; C089392:methacryloyloxydodecylpyridinium bromide; D017438:Bisphenol A-Glycidyl Methacrylate; C010882:chlorhexidine gluconate; D002710:Chlorhexidine