Addition of suitably-designed zwitterions improves the saturated water content of hydrophobic ionic liquids.
The saturated water content in a hydrophobic ionic liquid, 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)-imide, was improved from 0.4 wt% to 17.8 wt% by adding a 3-(1-butyl-3-imidazolio)propanesulfonate-type zwitterion in appropriate amounts. The mixture containing 17.8 wt% water successfully dissolved horse heart cytochrome c without significant change of the higher ordered structure.
Department of Biotechnology, Tokyo University of Agriculture and Technology, 2-24-16, Koganei, Tokyo, 184-8588, Japan.
Yoritsugu
Y
Ito
Yuki
Y
Kohno
Nobuhumi
N
Nakamura
Hiroyuki
H
Ohno
D000818:Animals; D045304:Cytochromes c / Q000737:chemistry / Q000378:metabolism; D006736:Horses / Q000378:metabolism; D057927:Hydrophobic and Hydrophilic Interactions; D007093:Imidazoles / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D014867:Water / Q000737:chemistry
C525963:1-butyl-3-methylimidazolium; D007093:Imidazoles; D052578:Ionic Liquids; D007477:Ions; D014867:Water; D045304:Cytochromes c