A ring expansion-glycosylation strategy toward the synthesis of septano-oligosaccharides.
A one-pot ring-expansion-glycosylation reaction was performed using 1,2-cyclopropanated sugars as glycosyl donors and carbohydrate O-nucleophiles as acceptors to provide septanohexose mimics of pyranose and furanose derivatives. The methodology was successfully extended to the synthesis of septano-oligosaccharides by adopting a divergent strategy as well as an iterative protocol.
School of Chemistry, University of Hyderabad, Hyderabad 500046, India. prssc@uohyd.ernet.in
Perali Ramu
PR
Sridhar
Patteti
P
Venukumar
D002241:Carbohydrates / Q000737:chemistry*; D003521:Cyclopropanes / Q000737:chemistry*; D006031:Glycosylation; D015394:Molecular Structure; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry
D002241:Carbohydrates; D003521:Cyclopropanes; D009844:Oligosaccharides