Repetitive TASER X26 discharge resulted in adverse physiologic events with a dose-response relationship related to the duration of discharge in anesthetized swine model.
The objectives of our study were to investigate the dose-response relationship of the TASER X26 discharge duration in an anesthetized swine model. Fourteen swines were anesthetized and then exposed to TASER X26 discharge for 5 sec (n = 5) or for 10 sec (n = 6). The sham control group (n = 3) was anesthetized and studied using the same protocol except TASER X26 discharges during the experiments. Hemodynamic parameters were obtained. Blood pressure and total peripheral resistance decreased significantly after TASER discharge and returned to baseline value at 15 min after 5 sec of TASER discharge but did not return to baseline values during the 30-min observation period after 10 sec of TASER discharge. Repetitive TASER X26 discharge resulted in adverse physiologic events with a dose-response relationship related to the duration of TASER X26 discharge in an anesthetized swine model.
Department of Emergency Medicine, Ajou University School of Medicine, San 5, Wonchon-dong, Yeongtong-gu, Suwon, Gyeonggi-do, 443-721, Korea.
Eun-Jung
EJ
Park
Sang-Cheon
SC
Choi
Jung-Hwan
JH
Ahn
Young-Gi
YG
Min
D000777:Anesthetics / Q000008:administration & dosage; D000818:Animals; D001639:Bicarbonates / Q000097:blood; D001794:Blood Pressure; D002302:Cardiac Output; D004338:Drug Combinations; D004558:Electric Stimulation / Q000295:instrumentation*; D006339:Heart Rate; D006863:Hydrogen-Ion Concentration; D019344:Lactic Acid / Q000097:blood; D023421:Models, Animal; D010101:Oxygen Consumption; D013552:Swine; D013992:Tiletamine / Q000008:administration & dosage; D014655:Vascular Resistance; D015041:Zolazepam / Q000008:administration & dosage
D000777:Anesthetics; D001639:Bicarbonates; D004338:Drug Combinations; C006131:tiletamine, zolazepam drug combination; D013992:Tiletamine; D019344:Lactic Acid; D015041:Zolazepam