An unusual case of vancomycin-related systemic reaction accompanied with severe thrombocytopenia mimicking pacemaker-related infective endocarditis: a case report and review of literature.
Vancomycin is a glycopeptide antibiotic used in the prophylaxis and treatment of infections caused by Gram-positive resistant bacteria. In recent years, several cases of vancomycin-associated immune thrombocytopenia have been presented as case reports, but the real incidence of this side effect is still unknown. In this report, we would like to present a case during which we confronted with a great dilemma: urgent removal of whole defibrillator system due to highly suspected infective endocarditis or leaving the defibrillator in place and simply switching vancomycin to another antibiotic agent and wait.
Cardiology Department, Ankara University, Ankara, Turkey, Basarcandemir@yahoo.com.
Basar
B
Candemir
Aynur
A
Aribuca
Cigdem
C
Koca
Ozgur Ulas
OU
Ozcan
Menekse
M
Gerede
Cansin T
CT
Kaya
D000900:Anti-Bacterial Agents / Q000009:adverse effects; D001327:Autoimmune Diseases / Q000139:chemically induced* / Q000175:diagnosis* / Q000517:prevention & control; D020878:Device Removal; D003937:Diagnosis, Differential; D004696:Endocarditis / Q000175:diagnosis* / Q000209:etiology* / Q000517:prevention & control; D005260:Female; D006801:Humans; D008875:Middle Aged; D010138:Pacemaker, Artificial / Q000009:adverse effects; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000175:diagnosis* / Q000517:prevention & control; D016896:Treatment Outcome; D014640:Vancomycin / Q000009:adverse effects*
D000900:Anti-Bacterial Agents; D014640:Vancomycin