[Individualized fluid-solid coupled model of intracranial aneurysms based on computed tomography angiography data].
OBJECTIVE
To establish an individualized fluid-solid coupled model of intracranial aneurysms based on computed tomography angiography (CTA) image data.


METHODS
The original Dicom format image data from a patient with an intracranial aneurysm were imported into Mimics software to construct the 3D model. The fluid-solid coupled model was simulated with ANSYS and CFX software, and the sensitivity of the model was analyzed. The difference between the rigid model and fluid-solid coupled model was also compared.


RESULTS
The fluid-solid coupled model of intracranial aneurysm was established successfully, which allowed direct simulation of the blood flow of the intracranial aneurysm and the deformation of the solid wall. The pressure field, stress field, and distribution of Von Mises stress and deformation of the aneurysm could be exported from the model. A small Young's modulus led to an obvious deformation of the vascular wall, and the walls with greater thicknesses had smaller deformations. The rigid model and the fluid-solid coupled model showed more differences in the wall shear stress and blood flow velocity than in pressure.


CONCLUSIONS
The fluid-solid coupled model more accurately represents the actual condition of the intracranial aneurysm than the rigid model. The results of numerical simulation with the model are reliable to study the origin, growth and rupture of the aneurysms.
Department of Neurosurgery, General Hospital of PLA, Beijing, China. wangfytxdy@sohu.com
Fuyu
F
Wang
Bainan
B
Xu
Zhenghui
Z
Sun
Lei
L
Liu
Chen
C
Wu
Xiaojun
X
Zhang
D001783:Blood Flow Velocity; D003198:Computer Simulation; D006439:Hemodynamics; D006801:Humans; D021621:Imaging, Three-Dimensional; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008955:Models, Cardiovascular; D012984:Software; D014057:Tomography, X-Ray Computed