Ecalmpsia: maternal and fetal outcome.
OBJECTIVE
To determine the incidence of eclampsia and examine the maternal and fetal outcome.


METHODS
A hundred and twenty consecutive admissions with eclampsia managed in Aminu Kano Teaching Hospital, Kano, Nigeria, were prospectively collated and analysed. Maternal and fetal morbidity and mortality were recorded.


RESULTS
The incidence of eclampsia was 1.2% of deliveries. Most (69.2%) of the patients had no antenatal care. In 93 (77.5%), the convulsions were controlled with diazepam, and 22.5% magnesium sulphate. Maternal complications rate was 39.2%, and use of Diazepam for control of convulsions increases complications (RR 3.12, 95% CI = 1.23-7.92, p= 0.02). Case fatality rate was 11.7%, diazepam use failed to achieve significant association with maternal death (RR 8.64, 95% CI = 0.53-140.29, p= 0.13). Stillbirth rate was 22.5% with significant association with diazepam use (RR 7.55, 95% CI= 1.07-3.09, p=0.04). Birth asphyxia was recorded in 39.1% and low birth weight in 25.8%.


CONCLUSIONS
The incidence of eclampsia in our hospital was very high, with corresponding high maternal and perinatal morbidity and mortality. Increased antenatal screening and use of magnesium sulphate to control convulsions will reduce the incidence and associated morbidity and mortality for both mother and fetus.
Department of Obstetrics and Gynaecology, Bayero University/Aminu Kano Teaching Hospital, Kano, Kano State, Nigeria. Tukur.jido@nhs.net
Tukur A
TA
Jido
D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use; D016001:Confidence Intervals; D003975:Diazepam / Q000009:adverse effects / Q000627:therapeutic use; D004461:Eclampsia / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008278:Magnesium Sulfate / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008428:Maternal Mortality; D008429:Maternal Welfare; D009549:Nigeria / Q000453:epidemiology; D016017:Odds Ratio; D054238:Perinatal Mortality; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011262:Pregnancy Trimester, Second; D011295:Prenatal Care / Q000706:statistics & numerical data; D011446:Prospective Studies; D012307:Risk Factors; D012640:Seizures / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology*; D050497:Stillbirth / Q000453:epidemiology*; D055815:Young Adult
D000927:Anticonvulsants; D008278:Magnesium Sulfate; D003975:Diazepam