Striking similarity: GATA-3 regulates ILC2 and Th2 cells.
Innate lymphoid cells (ILCs) and T helper (Th) cells share similar effector functions. In this issue of Immunity, Hoyler et al. (2012) and Mjosberg et al. (2012) demonstrate that GATA-3, a Th2 regulator, controls ILC2 differentiation, maintenance, and function.
Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. l-zhou@northwestern.edu
Liang
L
Zhou