Role of continuous glucose monitoring in the management of diabetic pregnancy.
Self-monitoring of blood glucose (SMBG) with intermittent capillary glucose fingerstick tests is currently the universally accepted method of glucose monitoring in pregnancy. During pregnancy SMBG tests are recommended before and after meals and before bed (typically 7 values/d). Continuous glucose monitoring systems consist of a disposable subcutaneous glucose-sensing device, electrochemically measuring glucose levels in subcutaneous tissues every 10 seconds, providing an average interstitial glucose value every 5 minutes (typically 288 values/d). From a research perspective this provides unprecedented insights into the pathophysiology of glucose metabolism, while from a clinical perspective it can facilitate enhanced patient-professional decision making, patient motivation, and improved glycaemic control. CGM has thus been described as a "roadmap for effective self-management" and as a "stepping stone in the journey towards a cure." This review will consider the lessons learned and evidence supporting current and potential future use of CGM in the management of diabetes in pregnancy.
MRCP, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham, NG7 2UH, UK. Niranjala.Hewapathirana@nuh.nhs.uk
Niranjala M
NM
Hewapathirana
Esther
E
O'Sullivan
Helen R
HR
Murphy
D001786:Blood Glucose / Q000378:metabolism; D015190:Blood Glucose Self-Monitoring; D016640:Diabetes, Gestational / Q000097:blood* / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D007743:Labor, Obstetric / Q000097:blood; D009765:Obesity / Q000097:blood / Q000150:complications / Q000503:physiopathology; D010353:Patient Education as Topic; D011247:Pregnancy
D001786:Blood Glucose