Therapy for spondyloarthritis: the role of extra-articular manifestations (eye, skin).
Spondyloarthritis can be considered one of the prototypes (besides rheumatoid arthritis) of an inflammatory rheumatic disease. The locomotor system is prominently involved with arthritis, enthesitis, dactylitis, sacroiliitis, and/or axial disease; but besides the rheumatologic component, other body systems are frequently affected. Extra-articular manifestations are all the medical conditions and symptoms that are not directly related to the locomotor system. Besides inflammatory bowel diseases, the major concept-related extra-articular manifestations are located in the eye (acute anterior uveitis) and the skin (psoriasis). This review focuses on the possible implications of these nonrheumatologic manifestations regarding the treatment of spondyloarthritis.
Department of Rheumatology, Ghent University Hospital, Ghent 9000, Belgium.
Philippe
P
Carron
Liesbet
L
Van Praet
Peggy
P
Jacques
Dirk
D
Elewaut
Filip
F
Van den Bosch
D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D011565:Psoriasis / Q000150:complications / Q000188:drug therapy*; D025241:Spondylarthritis / Q000150:complications / Q000188:drug therapy*; D016896:Treatment Outcome; D014606:Uveitis, Anterior / Q000150:complications / Q000188:drug therapy*
D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D007166:Immunosuppressive Agents