ART adherence changes among patients in community substance use treatment: a preliminary analysis from MACH14.
BACKGROUND
Opiate substitution treatment has been associated with better adherence to lifesaving antiretroviral medications, but the impact of other substance abuse treatment on adherence is unknown.


RESULTS
In this study, 215 patients who had been in adherence-focused research studies provided electronically-measured adherence data and a measure of whether the patient had recently been in substance abuse treatment. Recent engagement in substance abuse treatment was independently associated with significantly higher adherence, after covarying for recent substance use and other factors potentially affecting adherence.


CONCLUSIONS
The findings suggest that substance abuse treatment is associated with better adherence. Potential mechanisms by which substance abuse treatment improves adherence, such as more stability or more future-orientation, require further study.
Department of Psychiatry, Yale University School of Medicine, New Haven, CT; VA Connecticut Healthcare System, West Haven, CT, 06516, USA. Marc.Rosen@Yale.edu.
Marc I
MI
Rosen
Anne C
AC
Black
Julia H
JH
Arnsten
Jane M
JM
Simoni
Glann J
GJ
Wagner
Kathleen
K
Goggin
Robert H
RH
Remien
Carol E
CE
Golin
Yan
Y
Wang
David
D
Bangsberg
Honghu H
HH
Liu