[Research advances of interleukin-15 in anti-parasitic infection].
Interleukin-15 (IL-15) is a pro-inflammatory cytokine and also a chemotactic factor for a variety of immune cells, which participates in and regulates the inflammatory response and immune response to organisms. Up to now, the molecular structure and receptor of IL-15 have been widely researched, with important advances in its signal transduction way. However, its application in parasitology is still a relatively new topic. This article summarizes the latest research development of IL-15 in anti-parasitic infection, prospects its mechanism and application.
State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, CAAS, Lanzhou, 730046, China.
Jia-Yuan
JY
Li
Zhong-Yuan
ZY
Li
Yan
Y
Wang
Xing-Quan
XQ
Zhu
Min-Jun
MJ
Xu
D000818:Animals; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology; D016207:Cytokines / Q000276:immunology; D006373:Helminthiasis / Q000188:drug therapy / Q000276:immunology; D006376:Helminths / Q000187:drug effects; D019409:Interleukin-15 / Q000276:immunology* / Q000494:pharmacology* / Q000627:therapeutic use*; D007694:Killer Cells, Natural / Q000276:immunology; D010272:Parasitic Diseases / Q000188:drug therapy / Q000276:immunology; D011528:Protozoan Infections / Q000188:drug therapy / Q000276:immunology
D016207:Cytokines; D019409:Interleukin-15