Two new pregnane glycoside diesters from Caralluma russeliana.
Two new pregnane glycoside diesters, 1 and 2, in addition to two triterpenoids, 3 and 4, and two sterols, 5 and 6 were isolated and identified from Caralluma russeliana (family Asclepiadaceae). The new pregnane glycosides, 14β-benzoyloxy-15β-isovaleroyloxy-16α-hydroxypregn-20-on-3-O-[β-D-3-O-methyl-6-deoxyoleandrosopyranosyl-(1 → 4)-β-D-cymaropyranosyl-(1 → 4)-β-D-cymaropyranoside] (1) and 14β-isovaleroyloxy-15β-benzoyloxy-16α-hydroxypregn-20-on-3-O-[β-D-3-O-methyl-6-deoxyoleandrosopyranosyl-(1 → 4)-β-D-cymaropyranosyl-(1 → 4)-β-D-cymaropyranoside] (2), are different from those isolated previously from the same species in the sugar moiety, in being diester, in being 20-one and in being 5,6 saturated by hydrogen. The isolated compounds were identified on the basis of spectral data.
DSR, King Abdulaziz University, Jeddah - 21589, Saudi Arabia. mmohamed@kau.edu.sa
Mamdouh
M
Abdel-Mogib
Hanaa M
HM
Raghib
D029062:Apocynaceae / Q000737:chemistry*; D002725:Chloroform; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification*; D011278:Pregnanes / Q000737:chemistry / Q000302:isolation & purification*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification
D006027:Glycosides; D010840:Phytosterols; D010936:Plant Extracts; D011278:Pregnanes; D014315:Triterpenes; C574437:pregnane glycoside; D002725:Chloroform