Copper- and phosphine-ligand-free palladium-catalyzed direct allylation of electron-deficient polyfluoroarenes with allylic chlorides.
Simply id(all)ylic: a copper- and phosphine-ligand-free Pd-catalyzed direct allylation of electron-deficient polyfluoroarenes with allylic chlorides and the reaction mechanism are described. The simple catalytic system, broad substrate scope, and excellent functional-group compatibility of this protocol provides a useful and facile access to allylated polyfluoroarenes.
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, Lingling Lu, PR China.
Yan-Bo
YB
Yu
Shilu
S
Fan
Xingang
X
Zhang
D000498:Allyl Compounds / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D004583:Electrons; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D008024:Ligands; D010165:Palladium / Q000737:chemistry*; D010720:Phosphines / Q000737:chemistry*; D013237:Stereoisomerism
D000498:Allyl Compounds; D006845:Hydrocarbons, Fluorinated; D008024:Ligands; D010720:Phosphines; D010165:Palladium; D003300:Copper; C044646:phosphine; C023698:allyl chloride