Anxiety and depression and mortality among cognitively intact nursing home residents with and without a cancer diagnosis: a 5-year follow-up study.
BACKGROUND
Studies are lacking on how anxiety and depression symptoms influence mortality among cognitively intact older people in nursing homes (NHs) with a diagnosis of cancer versus those without cancer.


OBJECTIVE
We hypothesized that anxiety or depression was associated with survival and has greater effects on survival for residents with cancer than for those without cancer.


METHODS
A cohort of 227 cognitively intact (Clinical Dementia Rating scale score ≤0.5) older residents (60 with cancer and 167 without) from 30 NHs were followed from 2004-2005 to 2010. Data were collected using face-to-face interviews. Anxiety and depression were measured using the Hospital Anxiety and Depression Scale subscales. Sociodemographic variables and medical diagnoses were obtained from the records.


RESULTS
The overall survival after 5 years was 17% for residents with cancer and 22% for residents without cancer. Depression and comorbidity were associated with significantly worse survival independent of a cancer diagnosis. Residents with cancer and symptoms of anxiety (subscores at least 8) had worse survival than those without anxiety symptoms (P = .02), but this was not found among the noncancer group.


CONCLUSIONS
Independent of a cancer diagnosis, depression symptoms and comorbidity were associated with mortality among cognitive intact NH residents. Having symptoms of anxiety predicted shorter survival among residents with a cancer diagnosis.


CONCLUSIONS
Nurses should pay attention to depression symptoms among NH residents with and without a cancer diagnosis. Giving attention to residents with cancer and anxiety symptoms is especially important.
Faculty for Health and Social Sciences, Bergen University College, Norway. jorunn.drageset@hib.no
Jorunn
J
Drageset
Geir Egil
GE
Eide
Anette Hylen
AH
Ranhoff
D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000175:diagnosis / Q000401:mortality*; D003071:Cognition / Q000502:physiology; D015331:Cohort Studies; D016001:Confidence Intervals; D003866:Depressive Disorder / Q000175:diagnosis / Q000401:mortality*; D005260:Female; D005500:Follow-Up Studies; D015577:Geriatric Assessment; D006707:Homes for the Aged; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D016743:Mental Competency; D009369:Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000523:psychology*; D009735:Nursing Homes; D016016:Proportional Hazards Models; D012016:Reference Values; D018570:Risk Assessment; D012720:Severity of Illness Index; D016019:Survival Analysis