I2-CF3SO3H synergistic promoted sp3 C-H bond diarylation of aromatic ketones.
An I(2)-CF(3)SO(3)H synergistic promoted sp(3) C-H bond diarylation protocol was developed for the synthesis of 2,2-bis(4-(dimethylamino)phenyl)-1-aryl ethanones. The reaction performed well in the absence of any metal and ligand. It integrated three reactions with different mechanisms (iodination, Kornblum oxidation, and hydroarylation) in a single reactor.
Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Hubei, Wuhan 430079, PR China.
Yan-ping
YP
Zhu
Feng-cheng
FC
Jia
Mei-cai
MC
Liu
Liu-ming
LM
Wu
Qun
Q
Cai
Yang
Y
Gao
An-xin
AX
Wu
D007455:Iodine / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D008024:Ligands; D008698:Mesylates / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure
D007659:Ketones; D008024:Ligands; D008698:Mesylates; D007455:Iodine; C012077:trifluoromethanesulfonic acid