A new taurine derivative from South China Sea marine sponge Axinella sp.
A new (1) and two known (2 and 3) acylated taurine derivatives were isolated from the South China Sea marine sponge Axinella sp. The structures of the compounds were determined on the basis of spectral analysis. Compounds 1-3 did not inhibit the growth of hepatoma carcinoma cell (HepG2), lung carcinoma cell (A549), human breast carcinoma (MCF-7), no-small cell lung cancer (NCI-H460) and human nasopharyngeal carcinoma cell lines.
Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, PR China.
Riming
R
Huang
Yan
Y
Peng
Xuefeng
X
Zhou
Xianwen
X
Yang
Yonghong
Y
Liu
D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D047089:Axinella / Q000737:chemistry*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002681:China; D006801:Humans; D061986:MCF-7 Cells; D015394:Molecular Structure; D009792:Oceans and Seas; D013654:Taurine / Q000737:chemistry* / Q000494:pharmacology*
D000970:Antineoplastic Agents; D013654:Taurine