Pseudomonas aeruginosa, an emerging pathogen among burn patients in Kurdistan Province, Iran.
This study was conducted to determine the incidence of Pseudomonas aeruginosa infections among burn patients at Tohid Hospital, Iran. A total of 176 clinical specimens were obtained from 145 burn patients admitted to the burn unit of Tohid Hospital to detect the presence of P. aeruginosa. Antimicrobial susceptibility testing was conducted to detect extended spectrum beta-lactamase (ESBL) producing P. aeruginiosa using Clinical and Laboratory Standards Institute guidelines with the double disc synergy test (DDST). A polymerase chain reaction was used to detect PER-1 and OXA-10 among the isolates. The mean age, total body surface area and length of hospital stay among patients were 29 years, 37.7%, and 10 days, respectively. Kerosene was the commonest cause of burn (60%), followed by gas (30%). During the study, P. aeruginosa was detected in 100 isolates. The antibiotics they were most commonly resistant to were cefotaxime, ceftriaxone and ciprofloxacin. Of the 100 P. aeroginusa isolates, 28% were positive for ESBL production with the DDST, 48% and 52% were PER-1 and OXA-10 producers, respectively. The high frequency of PER-1 and OXA-10 producers at this hospital is of concern considering their potential spread among burn patients.
Department of Microbiology, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran. kalantar_enayat@yahoo.com
Enayat
E
Kalantar
Shadi
S
Taherzadeh
Tayeb
T
Ghadimi
Fariborz
F
Soheili
Heiman
H
Salimizand
Alireza
A
Hedayatnejad
D000328:Adult; D001431:Bacteriological Techniques; D002053:Burn Units; D002056:Burns / Q000382:microbiology*; D021821:Communicable Diseases, Emerging; D005260:Female; D005838:Genotype; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008297:Male; D016133:Polymerase Chain Reaction; D011552:Pseudomonas Infections / Q000453:epidemiology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification*; D018440:beta-Lactam Resistance