40-year old female with a sellar mass.
Pituicytoma is a rare, low-grade neoplasm that originates in the neurohypophysis of the pituitary gland. We report the clinicopathologic features of a pituicytoma arising in a 40-year-old female who presented with menstrual disorder for 2 months, clinically suggestive of a pituitary microadenoma. The tumor was marked by a proliferation of elongated cells arranged in bundles and interlacing fascicles. The tumor demonstrated positive staining with S-100 protein and patchy staining for glial fibrillary acid protein and Epithelial Membrane Antigen. The tumor did not stain with antibodies to Progesterone receptor and Neu-n. An MIB-1 labeling was lower than 1%. The tumor was subtotally resected and didn’t recur after the initial surgery.
Department of Pathology, 251 Hospital, People's Liberation Army, Zhangliakou, China.
Yong
Y
Huang
Juan
J
Quan
Hong
H
Su
Hai-xia
HX
Hu
Feng
F
Wang
D000236:Adenoma / Q000473:pathology*; D000328:Adult; D005260:Female; D006801:Humans; D010911:Pituitary Neoplasms / Q000473:pathology*