[Cerebral hemodynamic in acute phase of traumatic brain injury].
The study was aimed at investigating cerebral hemodynamic during acute phase of TBI in connection to ICP and initial S(Vj)O2. 80 patients with severe TBI were divided into 2 groups (with ICP > 20 mm Hg and ICP < 20 mm Hg) and 3 subgroups (with S(Vj)O2 < 55%, 55% < S(Vj)O2 < 75% and S(Vj)O2 > 75%). Minimal disturbances of cerebral hemodynamic were observed in patients with S(Vj)O2 from 55% to 75%. Autoregulation of cerebral blood flow in this group recovered on the 6th - 7th day after an injury. Low S(Vj)O2 corresponded to severe systemic and cerebral hemodynamic disturbances and often lethal outcome. In patients with high S(Vj)O2 disturbances of cerebral hemodynamic were insignificant and pattern of impeded perfusion was observed.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001930:Brain Injuries / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D006439:Hemodynamics; D006706:Homeostasis; D006801:Humans; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*; D013997:Time Factors; D015599:Trauma Severity Indices; D055815:Young Adult
D010100:Oxygen