Facile synthesis of nitriles via manganese oxide promoted oxidative dehydrosulfurization of primary thioamides.
In the presence of manganese oxides, dehydrosulfurization of various kinds of primary thioamides including aromatic, heterocyclic, and aliphatic ones efficiently proceeded to give the corresponding nitriles in high yields. The observed catalysis was truly heterogeneous, and manganese oxides could be reused.
Department of Applied Chemistry, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Tokyo 113-8656, Japan.
Kazuya
K
Yamaguchi
Kazuhisa
K
Yajima
Noritaka
N
Mizuno
D017895:Manganese Compounds / Q000737:chemistry*; D009570:Nitriles / Q000737:chemistry*; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry*; D012492:Salts / Q000737:chemistry; D013854:Thioamides / Q000737:chemistry*
D017895:Manganese Compounds; D009570:Nitriles; D010087:Oxides; D012492:Salts; D013854:Thioamides; C027424:manganese oxide; C015539:thiobenzamide; C014356:benzonitrile