Refractory temporal lobe epilepsy caused by angiocentric glioma complicated with focal cortical dysplasia: a surgical case series.
Angiocentric glioma (AG) is a rare, epilepsy-associated, low-grade neoplasm with a characteristic perivascular growth pattern. Here, we review the histological types, surgical interventions, and postoperative seizure in our three cases of AG with drug-resistant epilepsy. Some patients with AG present focal cortical dysplasia. For these patients, extended lesionectomy including the adjacent cortical dysplasia is necessary to achieve a seizure-free outcome. Surgical planning based on comprehensive evaluation of epilepsy and cortical dysplasia is therefore an important step for all patients.
Department of Functional Neurosurgery, Beijing Sanbo Brain Hospital, Capital Medical University, No. 50 Xiang Shan Yi-Ke-Song, Haidian District, Beijing, 100093, People's Republic of China.
Chang Qing
CQ
Liu
Jian
J
Zhou
XueLing
X
Qi
Guo Ming
GM
Luan
D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D004351:Drug Resistance; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D005260:Female; D005910:Glioma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D054220:Malformations of Cortical Development / Q000150:complications* / Q000473:pathology / Q000601:surgery; D012640:Seizures / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult