How to help the aging male? Current approaches to hypogonadism in primary care.
Hypogonadism is a common condition which occurs more frequently in older men. It is characterized by low testosterone (T) and is associated with symptoms which are often nonspecific. A key symptom is low libido, but it can also be associated with erectile dysfunction, reduced muscle mass and strength, increased body fat, reduced bone mineral density and osteoporosis, reduced vitality, and depressed mood. Hypogonadism is linked with a variety of comorbid conditions including erectile dysfunction, metabolic syndrome, diabetes, obesity, and osteoporosis. However, the condition is often underdiagnosed. T supplementation in hypogonadism is associated with a range of benefits including improved sexual function, increased lean body mass and/or reduced fat mass, and improved bone mineral density. A variety of T supplementation formulations are available. Although there is no evidence of increased risk of initiating prostate cancer with T supplementation, it is contraindicated in men with prostate cancer. It is important that primary care physicians are aware of both the signs and symptoms of hypogonadism, the monitoring and testing that is required and the merits and advantages of the various T preparations to ensure optimal management of the condition with a treatment approach that best suits patients' needs.
Faculty of Life Sciences, Bar Ilan University, Ramat Gan, Israel. blunenfeld@gmail.com
Bruno
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Lunenfeld
Stefan
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Arver
Ignacio
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Moncada
D Aled
DA
Rees
Heinrich M
HM
Schulte
D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D015897:Comorbidity; D000075202:Contraindications; D020249:Hormone Replacement Therapy / Q000379:methods; D006801:Humans; D007006:Hypogonadism / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011320:Primary Health Care; D013739:Testosterone / Q000627:therapeutic use; D014481:United States
D013739:Testosterone