Surgical debridement plus topical cyclosporine A in the treatment of vernal shield ulcers.
Vernal keratoconjunctivitis (VKC) is a severe chronic bilateral inflammation of the ocular surface characterized by seasonal exacerbations. Long-term prognosis is generally good; however, 6% develop sequelae responsible for permanent visual impairment. Corneal involvement is almost always present, consisting of punctate keratitis, shield ulcers (3-11%) and late corneal neovascularization. In recent years, topical cyclosporine A preparations at 2% in oil or at 1% in polyvinyl alcohol, have been successfully proposed for long term VKC treatments. It has been previously proven that medical treatment is not always sufficient, especially when it is employed to treat shield ulcer plaques. In such conditions, surgery may be effective for avoiding long term complications such as amblyopia, strabismus, infections and corneal perforation. In this paper, we show the efficacy of surgical debridement by means of simple scraping associated with topical cyclosporine treatment for the management of vernal shield ulcers complicated with plaques.
Anna Meyer Children's Hospital, Department of Pediatrics, University of Florence, Italy. r.captuto@meyer.it
R
R
Caputo
N
N
Pucci
F
F
Mori
C
C
De Libero
L
L
Di Grande
G M
GM
Bacci
D060433:Administration, Ophthalmic; D000293:Adolescent; D002648:Child; D003131:Combined Modality Therapy; D003233:Conjunctivitis, Allergic / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D003320:Corneal Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D016572:Cyclosporine / Q000008:administration & dosage*; D003646:Debridement; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D007558:Italy; D008297:Male; D009883:Ophthalmic Solutions; D012720:Severity of Illness Index; D016896:Treatment Outcome
D007166:Immunosuppressive Agents; D009883:Ophthalmic Solutions; D016572:Cyclosporine