Synthesis of (±)-γ-rubromycin via a new hypoiodite-catalytic oxidative cycloetherification.
A new synthesis of γ-rubromycin is presented through a new oxidative, bisbenzannulated spiroketalization as a key step which is catalyzed by an in situ generated hypoiodite species, developed previously by our group. This key transformation has high efficiency and convenient conditions. This is a new and efficient catalytic application for organohypoiodine reagents.
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, Gansu, PR China.
Liping
L
Wei
Jijun
J
Xue
Hongbiao
H
Liu
Wenjing
W
Wang
Ying
Y
Li
D002384:Catalysis; D003500:Cyclization; D004986:Ether / Q000737:chemistry*; D017613:Iodine Compounds / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011809:Quinones / Q000138:chemical synthesis*; D013141:Spiro Compounds / Q000737:chemistry
D017613:Iodine Compounds; D011809:Quinones; D013141:Spiro Compounds; D004986:Ether; C064949:gamma-rubromycin; C081961:hypoiodous acid