Recent development in aerosol devices for pulmonary vaccine delivery.
This review will discuss aerosol device technologies available for pulmonary vaccine deliveries. The possibilities of  adopting aerosol-generation for the purpose of pulmonary immunization are described. Aerosol-generation systems might offer  advantages in respect to vaccine stability and antigenicity. The noninvasive, relatively safe and low-cost net of pulmonary delivery  may provide great benefits to the public health vaccination campaign.
Center of Drug Evaluation and Research, Food and Drug Administration, Rockville, MD 20855, USA. dongmei.lu@fda.hhs.gov
Dong mei
Dm
Lu
D000280:Administration, Inhalation; D000336:Aerosols / Q000737:chemistry*; D000818:Animals; D016503:Drug Delivery Systems / Q000379:methods; D018928:Immunity, Mucosal / Q000276:immunology; D008168:Lung / Q000187:drug effects*; D009330:Nebulizers and Vaporizers; D020545:Respiratory Mucosa / Q000187:drug effects; D014611:Vaccination / Q000379:methods*; D014612:Vaccines / Q000008:administration & dosage*
D000336:Aerosols; D014612:Vaccines