title: Possible genetic component to the etiology of perigraft hygromas.
abstract: Perigraft hygroma is a known complication of prosthetic graft implantation. The specific etiology of perigraft hygromas is still unknown. We report 2 brothers who underwent open abdominal aortic aneurysm repairs with polytetrafluoroethylene grafts that developed progressively enlarging perigraft hygromas. This is the first case report of 2 brothers developing sac hygromas after open abdominal aortic aneurysm repair. This case demonstrates that there could be a genetic component associated with the development of perigraft hygromas and further investigation of genetic etiologies should be considered.
authors.affiliation: University of Iowa Hospitals and Clinics, Department of Surgery, Division of Vascular Surgery Iowa City, Iowa. USA. raphaelsun@gmail.com
authors.forename: Raphael C
authors.initials: RC
authors.lastname: Sun
authors.forename: Rachael
authors.initials: R
authors.lastname: Nicholson
authors.forename: William J
authors.initials: WJ
authors.lastname: Sharp
authors.forename: Melhem
authors.initials: M
authors.lastname: Sharafuddin
authors.forename: Timothy
authors.initials: T
authors.lastname: Kresowik
mesh_terms: D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging / Q000601:surgery*; D001019:Aortic Rupture / Q000000981:diagnostic imaging / Q000601:surgery*; D001027:Aortography / Q000379:methods; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000009:adverse effects* / Q000295:instrumentation; D057510:Endovascular Procedures / Q000009:adverse effects* / Q000295:instrumentation; D020022:Genetic Predisposition to Disease; D006801:Humans; D018191:Lymphangioma, Cystic / Q000000981:diagnostic imaging / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D010641:Phenotype; D011138:Polytetrafluoroethylene; D011474:Prosthesis Design; D014057:Tomography, X-Ray Computed; D019043:Vascular Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics*
chemical_list: D011138:Polytetrafluoroethylene