title: [Analysis of cytology in nasal smear of Japanese ceder pollinosis before and in season].
abstract: BACKGROUND
  In Japanese cedar pollinosis (JCP), some patients attacked nasal symptoms similar to pollinosis before season. Nobody knows the reason. We analyzed the nasal cytology from patients before and in season in 2010.
  
  
  METHODS
  Cytology of nasal smear by taking with nasal swab and Hansel's staining was performed. Degree of infiltrating cells are graded, and five types are divided; neutrophil only (N), neutrophil predominant (N> Eo/Mc), Eo/Mc outnumber or equal neutrophil (Eo/Mc≥ N), either Eosinophil or mast cell (Eo/Mc), and no infiltrating cells Cell-). Bacterial culture was enforced symptomatic patients of JCP with neutrophil predominant before season. Chi-square test was used for statistic analysis between before and in season, and among symptomatic JCP (SyJP), combined JCP with HD or other allergy (SyCJP), and asymptomatic JCP and CJCP (AsJP/CJP).
  
  
  RESULTS
  Before season, 58% of SyJP (n=83) was N with significantly higher (p< 0.005) compared to 21% of SyCJP (n=42) and 10% of AsJP/CJP (n=19). And before season, 45% of SyCJP was Eo/Mc with significantly higher (p< 0.005) than 9.6% of SyJP (n=83) and 10% of AsJP/CJP (n=19). In season (March), percentage of Eo/Mc in SyJP (n=42) and SyCJP (n=64) was of 58%, 56% respectively with statistically higher than before season in both groups. Fifty seven percentage of AsJP/CJP (n=19) was Cell- with much higher (p< 0.005) than SyJP and SyCJP (0∼7%) before and in season. Staphylococcus aureus in 25 and Staphylococcus epidermis in 12 patients were detected from 39 patients.
  
  
  CONCLUSIONS
  These results mean Staphylococcus species might involve symptom appearance of SyJP before season.
authors.affiliation: Otsuka ENT Clinic. otsuka46@u01.gate01.com
authors.forename: Hirokuni
authors.initials: H
authors.lastname: Otsuka
authors.forename: Masao
authors.initials: M
authors.lastname: Takanashi
authors.forename: Kimihiro
authors.initials: K
authors.lastname: Okubo
mesh_terms: D000328:Adult; D032485:Cryptomeria / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D009297:Nasal Mucosa / Q000166:cytology / Q000378:metabolism* / Q000382:microbiology; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology; D012621:Seasons