title: Enzyme-based D-flip-flop memory system.
abstract: The enzyme system was used to mimic the D-flip-flop memory unit. The reversible conversion of NAD(+) and NADH cofactors was used to encode the states of the memory unit, while a mixture of inhibitors was used as the Clock input and the substrates were used as the Data input.
authors.affiliation: Department of Chemistry and Biomolecular Science, Clarkson University, Potsdam, NY 13699, USA.
authors.forename: Kevin
authors.initials: K
authors.lastname: MacVittie
authors.forename: Jan
authors.initials: J
authors.lastname: Halámek
authors.forename: Evgeny
authors.initials: E
authors.lastname: Katz
mesh_terms: D000426:Alcohol Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000818:Animals; D039301:Computers, Molecular; D004581:Electronics / Q000295:instrumentation; D007770:L-Lactate Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D008958:Models, Molecular; D009243:NAD / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000201:enzymology*; D013552:Swine
chemical_list: D009243:NAD; D000426:Alcohol Dehydrogenase; D007770:L-Lactate Dehydrogenase