title: Splenic marginal zone lymphoma: a population-based study on the 2001-2008 incidence and survival in the United States.
abstract: The epidemiology of splenic marginal zone lymphoma (SMZL) in the United States has not been addressed. Eight years of data (2001-2008) from 17 registries of the Surveillance, Epidemiology and End Results (SEER) program were used for this study. Of the 116,411 cases of non-Hodgkin lymphoma (NHL) in the registries, 763 (0.6%) were SMZL. The overall annual age-adjusted incidence was 0.13 per 100,000 persons per year. The annual percent change in age-adjusted incidence was 4.81% overall (p < 0.05), and significantly increasing trends were found for patients who were white, male or aged 70 years and older (p < 0.05). The relative 5-year overall survival rate for patients with SMZL was 81% (95% confidence interval 75-86%). The incidence of SMZL was highest among whites, males and older patients. A steadily increasing trend in incidence was observed for SMZL. The relative 5-year overall survival rate was high.
authors.affiliation: Institute of Hospital Management, Chinese People's Liberation Army General Hospital, Beijing, P R China.
authors.forename: Lihua
authors.initials: L
authors.lastname: Liu
authors.forename: Haijun
authors.initials: H
authors.lastname: Wang
authors.forename: Yiming
authors.initials: Y
authors.lastname: Chen
authors.forename: Luis
authors.initials: L
authors.lastname: Rustveld
authors.forename: Gengxin
authors.initials: G
authors.lastname: Liu
authors.forename: Xianglin L
authors.initials: XL
authors.lastname: Du
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D049674:History, 21st Century; D006801:Humans; D015994:Incidence; D018442:Lymphoma, B-Cell, Marginal Zone / Q000453:epidemiology* / Q000266:history; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D018426:SEER Program; D013160:Splenic Neoplasms / Q000453:epidemiology* / Q000266:history; D016019:Survival Analysis; D014481:United States / Q000453:epidemiology / Q000208:ethnology