title: Protein palmitoylation and pathogenesis in apicomplexan parasites.
abstract: Apicomplexan parasites comprise a broad variety of protozoan parasites, including Toxoplasma gondii, Plasmodium, Eimeria, and Cryptosporidium species. Being intracellular parasites, the success in establishing pathogenesis relies in their ability to infect a host-cell and replicate within it. Protein palmitoylation is known to affect many aspects of cell biology. Furthermore, palmitoylation has recently been shown to affect important processes in T. gondii such as replication, invasion, and gliding. Thus, this paper focuses on the importance of protein palmitoylation in the pathogenesis of apicomplexan parasites.
authors.affiliation: Laboratorio de Parasitologia Molecular, Instituto Tecnológico de Chascomús (IIBINTECH), CONICET-Universidad Nacional de General San Martín, Intendente Marino Km 8,2, P.O. Box 164, Chascomús, B7130IWA Buenos Aires, Argentina.
authors.forename: Maria Martha
authors.initials: MM
authors.lastname: Corvi
authors.forename: Andres Mariano
authors.initials: AM
authors.lastname: Alonso
authors.forename: Marina Cecilia
authors.initials: MC
authors.lastname: Caballero
mesh_terms: D016782:Apicomplexa / Q000469:parasitology* / Q000502:physiology*; D054878:Lipoylation / Q000502:physiology*; D015800:Protozoan Proteins / Q000378:metabolism*
chemical_list: D015800:Protozoan Proteins