title: [Dynamic hierarchy of regulatory peptides. Structure of the induction relations of regulators as the target for therapeutic agents].
abstract: Based on the database information (literature period 1970-2010 gg.) on the effects of regulatory peptides (RP) and non-peptide neurotransmitters (dopamine, serotonin, norepi-nephrine, acetylcholine) it was analyzed of possible cascade processes of endogenous regulators. It was found that the entire continuum of RP and mediators is a chaotic soup of the ordered three-level compartments. Such a dynamic functional hierarchy of endogenous regulators allows to create start-up and corrective tasks for a variety of physiological functions. Some examples of static and dynamic patterns of induction processes of RP and mediators (that regulate the states of anxiety, depression, learning and memory, feeding behavior, reproductive processes, etc.) are considered.
authors.forename: S V
authors.initials: SV
authors.lastname: Koroleva
authors.forename: N F
authors.initials: NF
authors.lastname: Miasoedov
mesh_terms: D001007:Anxiety / Q000503:physiopathology; D016208:Databases, Factual; D006801:Humans; D007858:Learning / Q000502:physiology; D008568:Memory / Q000502:physiology; D058990:Molecular Targeted Therapy; D018377:Neurotransmitter Agents / Q000737:chemistry / Q000145:classification / Q000378:metabolism; D010455:Peptides / Q000737:chemistry / Q000145:classification / Q000378:metabolism; D049490:Systems Biology
chemical_list: D018377:Neurotransmitter Agents; D010455:Peptides