title: A registry of adult African American twins: the Carolina African American Twin Study of Aging.
abstract: Twin studies have seldom addressed ethnicity as one of the possible factors that create unique combinations of genetic and environmental influences. The major objective of the Carolina African American Twin Study of Aging is to identify the proportion of the genetic and environmental sources of individual variation in measures of health and behavioral factors in a sample of adult African Americans. Drawn from birth records from the State of North Carolina, this in-person study used public records to identify a cohort of twins between 22 and 92 years of age (X = 49.82 yrs, SD = 14.62), 39.7% of which were men. Members of non-intact twin pairs and siblings were also recruited to explore alternative models to the classic twin design. To date, the project has contributed to knowledge about blood pressure, forced expiratory volume, chronic illness, body mass index, and waist-hip ratio memory, personality, social, and demographic factors, mortality, and mental health.
authors.affiliation: Department of Psychology and Neuroscience, Duke University, USA. kwhit1@duke.edu
authors.forename: Keith E
authors.initials: KE
authors.lastname: Whitfield
mesh_terms: D000328:Adult; D001741:Black or African American / Q000235:genetics*; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000235:genetics* / Q000473:pathology; D015331:Cohort Studies; D004200:Diseases in Twins / Q000453:epidemiology* / Q000235:genetics; D015340:Epidemiologic Research Design; D005260:Female; D059647:Gene-Environment Interaction; D005824:Genetics, Behavioral; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D009657:North Carolina / Q000453:epidemiology; D018579:Patient Selection; D012042:Registries; D014429:Twins, Dizygotic / Q000235:genetics*; D014430:Twins, Monozygotic / Q000235:genetics*; D055815:Young Adult