title: [The development of a new marker of the training status in athletes].
abstract: The present study was based on the mathematical modeling of the middle molecular weight peptides (MMWP) concentration in the blood. On the one hand, MMWP are the products of partial protein catabolism, on the other hand, they act as inductors of protein synthesis. We have developed a complex hormonal marker that allows estimating the adaptive reactions in the organism of the athletes. The marker integrates the known hormonal indices, such as testosterone to cortisol ratio and aldosterone to cortisol ratio (-1,271 + 0,206 x 1n(testosterone) + 1,108 x 1n(aldosterone))/1n(cortisol). The use of a mathematical model for the prediction of MMWP levels in the rowers' blood provides a basis for the application of the new marker for the evaluation of physical conditions of the high-class athletes engaged in other sports. By way of example, the estimation of its informative value for the examination of swimmers has demonstrated significant positive correlation between the predicted and observed MMWP levels (r = 0,4187; p = 0,050). Practicability of applying the newly proposed hormonal marker for monitoring adaptative reactions in athletes is confirmed by significant correlation of calculated values with the real time the freestyle swimmers spend to cover a 50 m distance (r = - 0,4454; p = 0,001).
authors.forename: E A
authors.initials: EA
authors.lastname: Statsenko
authors.forename: A V
authors.initials: AV
authors.lastname: Kovkova
authors.forename: E V
authors.initials: EV
authors.lastname: Nekhaĭ
mesh_terms: D000328:Adult; D000450:Aldosterone / Q000097:blood*; D056352:Athletes; D015415:Biomarkers / Q000097:blood; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D008954:Models, Biological; D010809:Physical Fitness / Q000502:physiology*; D013550:Swimming / Q000502:physiology*; D013739:Testosterone / Q000097:blood*
chemical_list: D015415:Biomarkers; D013739:Testosterone; D000450:Aldosterone; D006854:Hydrocortisone