title: Fatal respiratory infections associated with rhinovirus outbreak, Vietnam.
abstract: During an outbreak of severe acute respiratory infections in 2 orphanages, Vietnam, 7/12 hospitalized children died. All hospitalized children and 26/43 children from outbreak orphanages tested positive for rhinovirus versus 9/40 control children (p = 0.0005). Outbreak rhinoviruses formed a distinct genetic cluster. Human rhinovirus is an underappreciated cause of severe pneumonia in vulnerable groups.
authors.affiliation: National Hospital of Pediatrics, Hanoi, Vietnam.
authors.forename: Le Thanh
authors.initials: le T
authors.lastname: Hai
authors.forename: Vu Thi Ngoc
authors.initials: VT
authors.lastname: Bich
authors.forename: Le Kien
authors.initials: le K
authors.lastname: Ngai
authors.forename: Nguyen Thi Ngoc
authors.initials: NT
authors.lastname: Diep
authors.forename: Phan Huu
authors.initials: PH
authors.lastname: Phuc
authors.forename: Viet Pham
authors.initials: VP
authors.lastname: Hung
authors.forename: Walter R
authors.initials: WR
authors.lastname: Taylor
authors.forename: Peter
authors.initials: P
authors.lastname: Horby
authors.forename: Nguyen Thanh
authors.initials: NT
authors.lastname: Liem
authors.forename: Heiman F L
authors.initials: HF
authors.lastname: Wertheim
mesh_terms: D020121:5' Untranslated Regions; D004196:Disease Outbreaks; D005260:Female; D016679:Genome, Viral; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010802:Phylogeny; D010850:Picornaviridae Infections / Q000453:epidemiology* / Q000401:mortality*; D012141:Respiratory Tract Infections / Q000453:epidemiology* / Q000401:mortality* / Q000821:virology; D012229:Rhinovirus / Q000145:classification / Q000235:genetics*; D012703:Serotyping; D014744:Vietnam / Q000453:epidemiology
chemical_list: D020121:5' Untranslated Regions