title: Jaw angiosarcoma. First case, with massive intraosseous localization, described in Italian literature.
abstract: Angiosarcoma (AS) is a rare non-epithelial malignant neoplasm arising from neoplastic vascular degeneration of endothelial cells. It usually occurs in soft tissue and skin. The incidence, according to American authors, is 1% of all soft tissue sarcomas. About 50% of AS is localized in head and neck region (scalp and face skin) and represents less than 1% of all malignancies of this district; the primitive intra- oral localization is rare, even rarer intraosseous development of AS in jaw bones. The Authors report a case of a mandibular intraosseus angiosarcoma with different peculiarities: the rarity of the location and mode of occurrence; in addition they have focused on clinical-histopathological and immunohistochemical charateristics.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University Magna Graecia, Catanzaro, Italy. Cristofaro@unicz.it
authors.forename: Maria Giulia
authors.initials: MG
authors.lastname: Cristofaro
authors.forename: Amerigo
authors.initials: A
authors.lastname: Giudice
authors.forename: Francesco
authors.initials: F
authors.lastname: Conforti
authors.forename: Valeria
authors.initials: V
authors.lastname: Zuccalà
authors.forename: Ida
authors.initials: I
authors.lastname: Barca
authors.forename: Davide
authors.initials: D
authors.lastname: Caruso
authors.forename: Mario
authors.initials: M
authors.lastname: Giudice
mesh_terms: D006394:Hemangiosarcoma / Q000473:pathology*; D006801:Humans; D007558:Italy; D007573:Jaw Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged