title: Iron store and free radicals in thalassemia.
abstract: Hyper-ferrous state is the result of multiple transfusions, whereby the iron excess in such conditions may be toxic to the organism. Patients suffering from thalassemia receive multiple transfusions. In the eastern part of India, both β(0)-thalassemia and heterozygous Eβ-thalassemia occur. This paper expresses the hyper-ferrous state, leading to iron overload in these two conditions and also reports the increased generation of free radicals, consequent to the iron overload.
authors.affiliation: Dept of Biochemistry, Vivekananda Institute of Medical Sciences, 99, Sarat Bose Road, 700 026 Kolkata, India.
authors.forename: K
authors.initials: K
authors.lastname: Goswami
authors.forename: S
authors.initials: S
authors.lastname: Ghosh
authors.forename: M
authors.initials: M
authors.lastname: Bandyopadhyay
authors.forename: K L
authors.initials: KL
authors.lastname: Mukherjee
keywords: Ferritin; Malondialdehyde; Thalassemia