title: [The methods of analysis of DNA methylation].
abstract: The article deals with the review of methods of analysis of DNA methylation as one of key mechanisms of regulation of gene expression. The sites of aberrant methylation are potential markers of neoplastic transformation. At the present time, the development of clinical tests is in the process on basis of analysis of methylation to make prognosis and to diagnose oncologic diseases, micro metastases detection and prenatal diagnostics of certain hereditary syndromes. The comparative analysis of methods applied in clinical practice and in carrying out fundamental studies was made.
authors.forename: Iu V
authors.initials: IuV
authors.lastname: filina
authors.forename: A G
authors.initials: AG
authors.lastname: Gabdulkhakova
authors.forename: M I
authors.initials: MI
authors.lastname: Arleevskaia
mesh_terms: D000818:Animals; D019175:DNA Methylation; D006801:Humans; D017422:Sequence Analysis, DNA / Q000379:methods*