title: A highly selective turn-on near-infrared fluorescent probe for hydrogen sulfide detection and imaging in living cells.
abstract: We have described a turn-on near-infrared fluorescent probe Cy-NO(2) based on nitro group reduction for intracellular H(2)S detection. The probe employs cyanine dye as a fluorophore, and is equipped with a nitro group as a fluorescent modulator. It is readily employed for assessing intracellular H(2)S level changes, and confocal imaging is achieved successfully.
authors.affiliation: Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, PR China.
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.forename: Fabiao
authors.initials: F
authors.lastname: Yu
authors.forename: Lingxin
authors.initials: L
authors.lastname: Chen
authors.forename: Hao
authors.initials: H
authors.lastname: Chen
authors.forename: Linjie
authors.initials: L
authors.lastname: Wang
authors.forename: Weiwei
authors.initials: W
authors.lastname: Zhang
mesh_terms: D000818:Animals; D002232:Carbocyanines / Q000737:chemistry*; D002460:Cell Line; D002470:Cell Survival; D003593:Cytoplasm / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006862:Hydrogen Sulfide / Q000032:analysis*; D018613:Microscopy, Confocal; D013050:Spectrometry, Fluorescence
chemical_list: D002232:Carbocyanines; D005456:Fluorescent Dyes; D006862:Hydrogen Sulfide