title: Colonic perforation in graft versus host disease: a case report.
abstract: Graft versus host disease (GVHD) is a phenomenon that occurs after allogeneic bone marrow transplants. Gastrointestinal (GI) manifestations of acute GVHD are common, but severe GI GVHD complications, such as bowel perforation, occur rarely and necessitate surgical intervention. To our knowledge, there are no recorded cases of colonic perforation resulting from GVHD with negative cultures for infectious agents such as cytomegalovirus. We present a case of large bowel perforation due to GVHD.
authors.affiliation: Department of Surgery, Division of General Surgery, Mount Sinai School of Medicine, New York, New York, USA.
authors.forename: Nandini C
authors.initials: NC
authors.lastname: Palaniappa
authors.forename: Laura
authors.initials: L
authors.lastname: Doyon
authors.forename: Celia M
authors.initials: CM
authors.lastname: Divino
mesh_terms: D016026:Bone Marrow Transplantation; D003108:Colonic Diseases / Q000175:diagnosis / Q000209:etiology*; D006086:Graft vs Host Disease / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007416:Intestinal Perforation / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology*; D014184:Transplantation, Homologous