title: A novel widespread interkingdom signaling circuit.
abstract: Extensive communication is believed to occur between eukaryotes and prokaryotes via signaling molecules; this field of research is now called interkingdom signaling. Recently, it has been discovered that many different plant-associated bacteria possess a protein closely related to the quorum-sensing (QS) LuxR-family protein that binds and responds to plant compounds. This LuxR protein does not have a cognate N-acyl homoserine lactone (AHL) signal synthase and therefore is regarded as a 'solo' or 'orphan'. The protein is involved in interkingdom signaling in rhizobia, xanthomonads, and pseudomonads, regulating processes important for plant-bacteria interaction. In this review, we focus on this new interkingdom signaling circuit, which is widespread among pathogenic and beneficial plant-associated bacteria.
authors.affiliation: International Centre for Genetic Engineering and Biotechnology, Padriciano 99, 34149 Trieste, Italy.
authors.forename: Juan F
authors.initials: JF
authors.lastname: González
authors.forename: Vittorio
authors.initials: V
authors.lastname: Venturi
mesh_terms: D000595:Amino Acid Sequence; D001419:Bacteria / Q000235:genetics*; D018407:Bacterial Physiological Phenomena; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D054884:Host-Pathogen Interactions; D008969:Molecular Sequence Data; D010802:Phylogeny; D018521:Plant Physiological Phenomena; D010944:Plants / Q000382:microbiology*; D053038:Quorum Sensing / Q000235:genetics; D012097:Repressor Proteins / Q000235:genetics; D016415:Sequence Alignment; D015398:Signal Transduction / Q000502:physiology*; D013559:Symbiosis; D015534:Trans-Activators / Q000235:genetics
chemical_list: D001426:Bacterial Proteins; D012097:Repressor Proteins; D015534:Trans-Activators; C064778:LuxR autoinducer binding proteins