title: Our orientation regarding the ductal carcinoma in situ of the breast.
abstract: OBJECTIVE
  The ductal carcinoma in situ is a malignant proliferation of mammary ductal epithelial cells without invasion beyond the basement membrane. The management of patients with DCIS is complex, controversial and has undergone changes over time.
  
  
  METHODS
  We treated 65 patients diagnosed with DCIS between 2002 and 2005. We surveyed women aged between 28 and 71 years (average age 51.4), the DCIS in 16 patients appeared as a palpable mass (about 2.2 cm) - group I and in 49 patients as microcalcifications detected on mammography - group II.
  
  
  RESULTS
  The most frequent histological type was found to be the comedocarcinoma. After 3 years of follow-up, we had 3 cases of recurrence (4.6%) in patients undergoing conservative surgery, with Van Nuys Prognostic Index between 3 and 4.
  
  
  CONCLUSIONS
  15-25% of cases of breast cancer are DCIS. Most of these are comedocarcinomas. Comedo form DCIS is an insidious cancer. Surgical treatment ranges from mastectomy to excision of the lesion, often the latter, followed by radiotherapy.
  
  
  CONCLUSIONS
  We prefer, with regard to surgical treatment, quadrantectomy with systematic control of the free margins. The search for the axillary sentinel node represents for us, too, the gold standard.
authors.affiliation: Department of Gerontology, Geriatrics and Metabolic Diseases, Second University of the Study of Naples School of Medicine, Unit of General and Geriatric Surgery. pasquale.petronella@unina2.it
authors.forename: Pasquale
authors.initials: P
authors.lastname: Petronella
authors.forename: Marco
authors.initials: M
authors.lastname: Scorzelli
authors.forename: Marco
authors.initials: M
authors.lastname: Ferretti
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Perna
authors.forename: Fulvio
authors.initials: F
authors.lastname: Freda
authors.forename: Silvestro
authors.initials: S
authors.lastname: Canonico
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000628:therapy*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000628:therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged