title: Contrast-induced nephropathy in patients with ST elevation myocardial infarction treated with primary percutaneous coronary intervention.
abstract: We assessed the relationship between contrast-induced nephropathy (CIN) and SYNTAX score (SS) and serum uric acid (SUA) levels in patients with ST elevation myocardial infarction (STEMI). A total of 835 STEMI patients in whom primary percutaneous coronary intervention was performed in our cardiology clinic were included in this study (615 male, 220 female; mean age 58.1 ± 12.2 years). The patients were divided into 2 groups (CIN and non-CIN). Contrast-induced nephropathy was observed in 9.6% (80) of patients; SS (13.9 ± 6.2/22.1 ± 5.8) and SUA (5.1 ± 0.9/6.2 ± 0.9) values in the CIN group were higher compared with the non-CIN group (P < .001, for all). All SS (95% confidence interval [CI] = 1.136-1.250, P = .001), SUA (95% CI = 1.877-3.236, P = .002), and diabetes (95% CI = 0.998-1.039, P = .026) were independent predictors of CIN in logistic regression analysis. Procedures that can prevent CIN may be beneficial in patients at high risk as identified by the SS and SUA levels.
authors.affiliation: 1Department of Cardiology, Adana Numune Education and Research Hospital,  Adana, Turkey.
authors.forename: Zafer
authors.initials: Z
authors.lastname: Elbasan
authors.forename: Durmuş Yildiray
authors.initials: DY
authors.lastname: Şahin
authors.forename: Mustafa
authors.initials: M
authors.lastname: Gür
authors.forename: Osman
authors.initials: O
authors.lastname: Kuloğlu
authors.forename: Ali
authors.initials: A
authors.lastname: Kivrak
authors.forename: Yahya Kemal
authors.initials: YK
authors.lastname: Içen
authors.forename: Caner
authors.initials: C
authors.lastname: Türkoglu
authors.forename: Arafat
authors.initials: A
authors.lastname: Yildirim
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Özdogru
authors.forename: Murat
authors.initials: M
authors.lastname: Çayli
mesh_terms: D000328:Adult; D000368:Aged; D003287:Contrast Media / Q000009:adverse effects*; D017023:Coronary Angiography / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000097:blood / Q000139:chemically induced* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000000981:diagnostic imaging* / Q000628:therapy; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects*; D015995:Prevalence; D014527:Uric Acid / Q000097:blood*
chemical_list: D003287:Contrast Media; D014527:Uric Acid
keywords: SYNTAX score; contrast media; myocardial infarction; nephropathy; uric acid