title: Turn-on fluorescent chemosensor for Zn(II) via ring opening of rhodamine spirolactam and their live cell imaging.
abstract: A new rhodamine based selective and sensitive turn-on fluorescent Zn(2+)chemosensor has been developed. A prominent fluorescence enhancement was found in the presence of Zn(2+), which was accompanied by changes in the absorption spectrum. The new sensor showed 'naked-eye' detection of Zn(2+) ions: a color change of the solution from colorless to pink. Furthermore, by means of confocal laser scanning microscopy experiments, it has been demonstrated that it can be used as a fluorescent probe for monitoring Zn(2+) in living cells.
authors.affiliation: School of Chemistry, Madurai Kamaraj University, Madurai-625021, Tamilnadu, India.
authors.forename: Gandhi
authors.initials: G
authors.lastname: Sivaraman
authors.forename: Thangaraj
authors.initials: T
authors.lastname: Anand
authors.forename: Duraisamy
authors.initials: D
authors.lastname: Chellappa
mesh_terms: D002470:Cell Survival; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D003124:Colorimetry; D004926:Escherichia coli / Q000166:cytology; D057054:Molecular Imaging / Q000379:methods*; D012235:Rhodamines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D015032:Zinc / Q000032:analysis* / Q000737:chemistry
chemical_list: D012235:Rhodamines; C584450:ZRP-1 compound; D015032:Zinc