title: CMOS cell sensors for point-of-care diagnostics.
abstract: The burden of health-care related services in a global era with continuously increasing population and inefficient dissipation of the resources requires effective solutions. From this perspective, point-of-care diagnostics is a demanded field in clinics. It is also necessary both for prompt diagnosis and for providing health services evenly throughout the population, including the rural districts. The requirements can only be fulfilled by technologies whose productivity has already been proven, such as complementary metal-oxide-semiconductors (CMOS). CMOS-based products can enable clinical tests in a fast, simple, safe, and reliable manner, with improved sensitivities. Portability due to diminished sensor dimensions and compactness of the test set-ups, along with low sample and power consumption, is another vital feature. CMOS-based sensors for cell studies have the potential to become essential counterparts of point-of-care diagnostics technologies. Hence, this review attempts to inform on the sensors fabricated with CMOS technology for point-of-care diagnostic studies, with a focus on CMOS image sensors and capacitance sensors for cell studies.
authors.affiliation: METU-MEMS Research and Application Center, Middle East Technical University, Ankara 06800, Turkey. yekbun@metu.edu.tr
authors.forename: Yekbun
authors.initials: Y
authors.lastname: Adiguzel
authors.forename: Haluk
authors.initials: H
authors.lastname: Kulah
mesh_terms: D000818:Animals; D003584:Cytological Techniques / Q000295:instrumentation*; D006696:Holography / Q000295:instrumentation; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D008670:Metals / Q000737:chemistry; D008853:Microscopy / Q000295:instrumentation; D010087:Oxides / Q000737:chemistry; D019095:Point-of-Care Systems; D012666:Semiconductors
chemical_list: D008670:Metals; D010087:Oxides
keywords: CMOS; cell sensing; point-of-care diagnostics