title: Two new cholic acid derivatives from the marine ascidian-associated bacterium Hasllibacter halocynthiae.
abstract: The investigation of secondary metabolites in liquid cultures of a recently discovered marine bacterium, Hasllibacter halocynthiae strain KME 002T, led to the isolation of two new cholic acid derivatives. The structures of these compounds were determined to be 3,3,12-trihydroxy-7-ketocholanic acid (1) and 3,3,12-trihydroxy-7-deoxycholanic acid (2) through HRFABMS and NMR data analyses.
authors.affiliation: Natural Medicine Center, Korea Institute of Science and Technology-KIST, Gangneung 210-340, Korea.
authors.forename: Sung Hun
authors.initials: SH
authors.lastname: Kim
authors.forename: Yun Kyung
authors.initials: YK
authors.lastname: Shin
authors.forename: Young Chang
authors.initials: YC
authors.lastname: Sohn
authors.forename: Hak Cheol
authors.initials: HC
authors.lastname: Kwon
mesh_terms: D000818:Animals; D001419:Bacteria / Q000737:chemistry*; D019826:Cholic Acid / Q000737:chemistry / Q000302:isolation & purification*; D002853:Chromatography, Liquid; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D012623:Seawater; D014561:Urochordata / Q000382:microbiology*
chemical_list: D019826:Cholic Acid