title: Acute bacterial prostatitis in humans: current microbiological spectrum, sensitivity to antibiotics and clinical findings.
abstract: OBJECTIVE
  To assess the current microbiological profile and sensitivity to antibiotics in patients with acute bacterial prostatitis (ABP).
  
  
  METHODS
  In the period 2003-2010, we treated 192 ABP patients, aged from 18 to 85 years (average 56.3 years). We performed a biochemical examination including a microbiological urine examination. After admission, we immediately began the empirical antibacterial treatment.
  
  
  RESULTS
  The clinical picture was dominated by pain, prostate enlargement and failure of micturition in 185 (96.4%) patients; 14 (7.3%) patients had acute urinary retention where epicystostomy was necessary. Fever occurred in 177 (92.2%) patients and Escherichia coli was the most frequent etiological agent detected in 103 (53.7%) patients followed by Pseudomonas aeruginosa and Klebsiella species. In 16 (8.3%) patients we found 2 bacteriological strains. Sterile urine was found in 65 (33.8%) patients. Fluoroquinolones, aminoglycosides and cephalosporins were used most frequently. 147 (76.6%) patients were treated according to the microbiological results. Overview of resistance shows an increase in resistance to fluoroquinolones. In 14 (7.3%) patients there was progression to urosepsis.
  
  
  CONCLUSIONS
  Clinicians should consider local drug-resistance patterns when choosing antibiotics and should adjust the therapy on the basis of bacterial cultures and local sensitivity to antibiotics.
authors.affiliation: Department of Urology, P.J. Šafárik University, Medical Faculty and L. Pasteur University Hospital, SNP 1, Košice, Slovak Republic. vincent.nagy @ upjs.sk
authors.forename: Vincent
authors.initials: V
authors.lastname: Nagy
authors.forename: Dušan
authors.initials: D
authors.lastname: Kubej
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011472:Prostatitis / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents