title: Biochemical activity of selenium and glutathione on country made liquor (CML) induced hepatic damage in rats.
abstract: The serum and hepatic enzymes of rats were studied after exposed to country made liquor (CML) along with two chelating agents (glutathione and Selenium). There was a significant increase in several serum enzyme levels (viz., aspartate transaminase, alanine transaminase, alkaline phosphatase, sorbitol dehydrogenase, glutamate dehydrogenase, bilirubin) and decrease in various hepatic enzymes (Succinic dehydrogenase, Glucose 6-phosphatase, 5'Nucleotiease, Acid phosphatase, Acid ribonuclease, Cytochrome P-450) due to repeated administration of CML (2ml/100g of body weight). Results of this study revealed that the GSH and Se could give a significant protective action in serum and hepatic enzymes of CML exposed rats.
authors.affiliation: Department of Biochemistry, Selvamm Arts & Science College, Namakkal.
authors.forename: G
authors.initials: G
authors.lastname: Kumar
authors.forename: G Sharmila
authors.initials: GS
authors.lastname: Banu
authors.forename: M Rajasekara
authors.initials: MR
authors.lastname: Pandian
keywords: CML; Chelating agents; Hepatoprotection; Serum and Hepatic enzymes