title: No harmful effect of dialysis-induced hypotension on the myocardium in patients who have normal ejection fraction and a negative exercise test.
abstract: BACKGROUND
  We investigated the effects of dialysis-induced hypotension (DIH) on the myocardium of patients who have a normal ejection fraction and normal treadmill stress tests.
  
  
  METHODS
  This study included 26 end-stage renal disease (ESRD) patients with DIH, 30 ESRD patients without DIH (non-DIH), and 30 control subjects. Mitral-myocardial systolic velocity (MSV), the mitral E'/A' ratio, the left ventricle filling pressure index (E/E' ratio), tricuspid-MSV, and the tricuspid E'/A' ratio were calculated.
  
  
  RESULTS
  Biventricular systolic and diastolic functions were impaired in dialysis patients. The mitral and tricuspid MSV were similar between DIH and non-DIH patients (8.03 ± 0.90 cm/s vs. 8.31 ± 1.68 cm/s, p = 0.896, and 13.27 ± 2.97 cm/s vs. 13.15 ± 2.37 cm/s, p = 0.980). Mitral and tricuspid E'/A' were similar between DIH and non-DIH patients. (1.30 ± 0.53 vs. 1.16 ± 0.56, p = 0.695, and 0.70 ± 0.24 vs. 0.68 ± 0.33, p = 0.976). Likewise, the E/E' ratio was similar between DIH and non-DIH patients (8.20 ± 2.83 vs. 8.28 ± 2.53, p = 0.990).
  
  
  CONCLUSIONS
  Although biventricular systolic and diastolic function is impaired in dialysis patients compared to controls, DIH episodes did not have an adverse effect on the myocardial functions.
authors.affiliation: Division of Cardiology, Goztepe Medical Park Hospital, Istanbul, Turkey. hakan_fotbolcu @ yahoo.com
authors.forename: Hakan
authors.initials: H
authors.lastname: Fotbolcu
authors.forename: Vecih
authors.initials: V
authors.lastname: Oduncu
authors.forename: Emre
authors.initials: E
authors.lastname: Gürel
authors.forename: Cihan
authors.initials: C
authors.lastname: Cevik
authors.forename: Ayhan
authors.initials: A
authors.lastname: Erkol
authors.forename: Kıvılcım
authors.initials: K
authors.lastname: Özden
authors.forename: Bahtisen
authors.initials: B
authors.lastname: Guven
authors.forename: Akın
authors.initials: A
authors.lastname: Dayan
authors.forename: Gökçe
authors.initials: G
authors.lastname: Şirin
authors.forename: Yelda
authors.initials: Y
authors.lastname: Basaran
mesh_terms: D000328:Adult; D005080:Exercise Test / Q000379:methods; D005260:Female; D006321:Heart / Q000502:physiology*; D006801:Humans; D007022:Hypotension / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology*; D007676:Kidney Failure, Chronic / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects* / Q000639:trends; D013318:Stroke Volume / Q000502:physiology*; D016896:Treatment Outcome