title: [Efficacy of cytoflavin in patients with hypertonic encephalopathy and constitutional venous insufficiency].
abstract: We examined 60 patients with constitutional venous insufficiency, suffering from hypertensive encephalopathy of I and II stages, mean age 43,4± 6,3 years. Patients of the main group (n=30) received Cytoflavin (2 tablets twice a day) and standard therapy (acetylsalicylic acid and antihypertensive drugs). Thirty patients of the parallel group received only standard therapy. At the 25th day of the study, there were the decrease in the number of complaints, including specific "venous complaints", the reduction of cephalalgia syndrome, asthenic and autonomic disorders; the improvement of quality of life and better cerebral hemodynamics on all structural and functional levels.
authors.forename: L A
authors.initials: LA
authors.lastname: Belova
authors.forename: V V
authors.initials: VV
authors.lastname: Mashin
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Kolotik-Kameneva
authors.forename: N V
authors.initials: NV
authors.lastname: Belova
authors.forename: A V
authors.initials: AV
authors.lastname: Byrina
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Evstigneeva
authors.forename: V V
authors.initials: VV
authors.lastname: Abramova
mesh_terms: D000328:Adult; D001925:Brain Damage, Chronic / Q000188:drug therapy* / Q000209:etiology*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D005260:Female; D005486:Flavin Mononucleotide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000150:complications*; D007290:Inosine Diphosphate / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009536:Niacinamide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D011788:Quality of Life; D013386:Succinates / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome; D014689:Venous Insufficiency / Q000188:drug therapy*
chemical_list: D004338:Drug Combinations; D013386:Succinates; C507879:cytoflavin; D009536:Niacinamide; D005486:Flavin Mononucleotide; D007290:Inosine Diphosphate