title: Oral fluid nanosensor test: saliva as a diagnostic tool for oral health.
abstract: High-impact diseases, especially cancer, are challenging to diagnose without supplementing laboratory testing. Even with laboratory tools, definitive diagnosis often remains elusive. The oral fluid nanosensor test technology platform combines cutting-edge technologies--such as self-assembled monolayers, bionanotechnology, cyclic enzymatic amplification, and microfluidics--with several well-established techniques including microinjection molding, hybridization-based detection, and molecular purification. The intended use of the OFNASET is for the point-of-care multiplex detection of salivary biomarkers for oral cancer.
authors.affiliation: Department of Oral Medicine and Radiology, Dr. Syamala Reddy Dental College Hospital and Research Centre affiliated to Rajiv Gandhi University of Health Sciences, Bangalore, Karnataka, India. drpujarimr@yahoo.co.in
authors.forename: Mallayya
authors.initials: M
authors.lastname: Pujari
authors.forename: Shraddha
authors.initials: S
authors.lastname: Bahirwani
authors.forename: P
authors.initials: P
authors.lastname: Balaji
authors.forename: Rachna
authors.initials: R
authors.lastname: Kaul
authors.forename: Bina
authors.initials: B
authors.lastname: Shah
authors.forename: Deepak
authors.initials: D
authors.lastname: Daryani
authors.forename: Sidra
authors.initials: S
authors.lastname: Iqbal
mesh_terms: D015415:Biomarkers / Q000032:analysis; D015374:Biosensing Techniques; D004194:Disease; D006801:Humans; D046210:Microfluidic Analytical Techniques; D009059:Mouth Diseases / Q000175:diagnosis*; D036103:Nanotechnology; D019095:Point-of-Care Systems; D012463:Saliva / Q000737:chemistry*
chemical_list: D015415:Biomarkers