title: CuAAC click functionalization of azide-modified nanodiamond with a photoactivatable CO-releasing molecule (PhotoCORM) based on [Mn(CO)3(tpm)]+.
abstract: The copper-catalyzed 1,3-dipolar azide-alkyne cycloaddition (CuAAC) was used for the first time to attach a biologically active carbon monoxide delivery agent to modified nanodiamond (ND) as a highly biocompatible carrier. The [Mn(CO)(3)(tpm)](+) photoactivatable CO-releasing molecule (PhotoCORM) on the surface retained the carbon monoxide release properties of the parent compound as shown with the myoglobin assay.
authors.affiliation: Institut für Anorganische Chemie, Julius-Maximilians-Universität Würzburg, Am Hubland, D-97074 Würzburg, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Dördelmann
authors.forename: Thomas
authors.initials: T
authors.lastname: Meinhardt
authors.forename: Thomas
authors.initials: T
authors.lastname: Sowik
authors.forename: Anke
authors.initials: A
authors.lastname: Krueger
authors.forename: Ulrich
authors.initials: U
authors.lastname: Schatzschneider
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002248:Carbon Monoxide / Q000737:chemistry*; D002384:Catalysis; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry*; D061565:Cycloaddition Reaction; D058612:Nanodiamonds / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D055668:Photochemical Processes; D011720:Pyrazoles / Q000737:chemistry
chemical_list: D000480:Alkynes; D001386:Azides; D058612:Nanodiamonds; D009942:Organometallic Compounds; D011720:Pyrazoles; D003300:Copper; D002248:Carbon Monoxide