title: Disease related knowledge and quality of life: a descriptive study focusing on hypertensive population in Pakistan.
abstract: OBJECTIVE
  This study aims to evaluate association between Health related quality of lifeand disease state knowledge among hypertensive population of Pakistan.
  
  
  METHODS
  A cross sectional descriptive study was undertaken with a representative cohort of hypertension patients. Using prevalence based sampling technique, a total of 385 hypertensive patients were selected from two public hospitals of Quetta city, Pakistan. Hypertension Fact Questionnaire (HFQ) and European Quality of Life scale (EQ-5D) were used for data collection. Statistical Package for the Social Sciences 16.0 was used to compute descriptive analysis of patients' demographic and disease related information. Categorical variables were described as percentages while continuous variables were expressed as mean ± standard deviation (SD). Spearman's rho correlation was used to identify the association between study variables.
  
  
  RESULTS
  The mean (SD) age of the patients was 39.02 (6.59), with 68.8% males (n=265). The mean (SD) duration of hypertension was 3.01 (0.93) years. Forty percent (n=154) had bachelor degree with 34.8% (n=134) working in private sector. Almost forty one percent (n=140) had monthly income of more than 15000 Pakistan rupees per month with 75.1% (n=289) having urban residency. The mean EQ-5D descriptive score (0.46±0.28) and EQ-VAS score (63.97±6.62) indicated lower HRQoL in our study participants. Mean knowledge score was 8.03 ± 0.42. Correlation coefficient between HRQoL and knowledge was 0.208 (p< 0.001), indicating a week positive association.
  
  
  CONCLUSIONS
  Results of this study highlight hypertension knowledge to be weakly associated with HRQoL suggesting that imparting knowledge to patients do not necessarily improve HRQoL. More attention should be given to identify individualized factors affecting HRQoL.
authors.affiliation: Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, 11800, Minden, Pinang, Malaysia.
authors.forename: Fahad
authors.initials: F
authors.lastname: Saleem
authors.forename: Mohamed Azmi
authors.initials: MA
authors.lastname: Hassali
authors.forename: Asrul Akmal
authors.initials: AA
authors.lastname: Shafie
authors.forename: Muhammad
authors.initials: M
authors.lastname: Atif
authors.forename: Noman
authors.initials: N
authors.lastname: Ul Haq
authors.forename: Hisham
authors.initials: H
authors.lastname: Aljadhey
keywords: Correlation.; Health Related Quality of Life; Hypertension; Knowledge