title: ClusterMine360: a database of microbial PKS/NRPS biosynthesis.
abstract: ClusterMine360 (http://www.clustermine360.ca/) is a database of microbial polyketide and non-ribosomal peptide gene clusters. It takes advantage of crowd-sourcing by allowing members of the community to make contributions while automation is used to help achieve high data consistency and quality. The database currently has >200 gene clusters from >185 compound families. It also features a unique sequence repository containing >10 000 polyketide synthase/non-ribosomal peptide synthetase domains. The sequences are filterable and downloadable as individual or multiple sequence FASTA files. We are confident that this database will be a useful resource for members of the polyketide synthases/non-ribosomal peptide synthetases research community, enabling them to keep up with the growing number of sequenced gene clusters and rapidly mine these clusters for functional information.
authors.affiliation: Department of Chemistry, Center for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada.
authors.forename: Kyle R
authors.initials: KR
authors.lastname: Conway
authors.forename: Christopher N
authors.initials: CN
authors.lastname: Boddy
mesh_terms: D030541:Databases, Genetic; D005798:Genes, Bacterial; D020407:Internet; D005810:Multigene Family; D046908:Peptide Biosynthesis, Nucleic Acid-Independent; D010453:Peptide Synthases / Q000145:classification / Q000235:genetics*; D010802:Phylogeny; D048630:Polyketide Synthases / Q000145:classification / Q000235:genetics*; D061065:Polyketides / Q000378:metabolism; D012984:Software
chemical_list: D061065:Polyketides; D048630:Polyketide Synthases; D010453:Peptide Synthases; C104385:non-ribosomal peptide synthase