title: Pressure wire used to measure gradient in chronic mesenteric ischemia.
abstract: Chronic mesenteric ischemia is a rare disorder in the United States. Frequently, its symptoms correlate poorly with the angiographically apparent degree of mesenteric artery stenosis. Measuring the pressure gradient with a small-caliber catheter is an established means of determining whether a particular stenosis is flow-limiting, thus guiding the interventional decision when stenoses are of indeterminate angiographic significance. Using a 0.014-in guidewire, however, is potentially more accurate because it eliminates any measurement error attributable to the use of a larger, potentially obstructive catheter. We present a case of chronic mesenteric ischemia in a 70-year-old woman who had abdominal pain with multiple possible causes. We used a 0.014-in pressure wire to calculate pressure gradients and guide our decision to stent tandem lesions in the superior mesenteric artery. After revascularization, the patient's symptoms improved dramatically. To the best of our knowledge, this is the first published case in which a pressure wire was used to measure a pressure gradient in chronic mesenteric ischemia.
authors.affiliation: Division of Adult Cardiology, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, Texas 77030, USA.
authors.forename: Bashar
authors.initials: B
authors.lastname: Hannawi
authors.forename: Wilson W
authors.initials: WW
authors.lastname: Lam
authors.forename: George Antoine
authors.initials: GA
authors.lastname: Younis
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon / Q000295:instrumentation; D062186:Arterial Pressure; D001795:Blood Pressure Determination / Q000379:methods*; D003251:Constriction, Pathologic; D004867:Equipment Design; D005260:Female; D006801:Humans; D007511:Ischemia / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D017538:Mesenteric Artery, Superior / Q000000981:diagnostic imaging / Q000503:physiopathology; D065666:Mesenteric Ischemia; D008641:Mesenteric Vascular Occlusion / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy; D011237:Predictive Value of Tests; D011859:Radiography; D015607:Stents; D014160:Transducers, Pressure; D016896:Treatment Outcome; D062666:Vascular Access Devices; D014652:Vascular Diseases / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy
keywords: Mesenteric arteries/pathology; mesenteric ischemia, chronic; mesenteric vascular occlusion/diagnosis/therapy; mesentery/blood supply; peripheral vascular diseases/therapy; pressure gradient; pressure wire; splanchnic circulation