title: Weight of the resected specimen after transurethral resection as a new predictive variable for recurrence of non-muscle-invasive bladder tumour.
abstract: OBJECTIVE
  To evaluate the role of the weight of the resected specimen after transurethral resection as a predictive factor for recurrence and progression of non-muscle-invasive bladder tumour (NMIBT).
  
  
  METHODS
  The weight of the resected tumour was measured consecutively in 144 subjects who underwent transurethral resection of bladder tumours at our institution. The median (interquartile range [IQR]) follow-up was 58 (61.3) months. The probability of recurrence and progression at 1 and 5 years were calculated using the currently accepted variables. Thresholds for the specimen weight were determined according to percentiles and receiver-operating characteristic curves.
  
  
  RESULTS
  The median (IQR) weight of the specimen was 6 (16) g. Multivariate analysis showed that the weight of the resected specimen was an independent predictive risk factor for recurrence at a threshold value of 6 g with a hazard ratio of 1.7 (95% confidence interval: 1.048-2.761) P = 0.03. Progression was not associated with the weight of the resected specimen.
  
  
  CONCLUSIONS
  The weight of the resected specimen is a new variable for predicting the risk of recurrence of NMIBT. Tumours weighing >6 g, according to the present data, have a 1.7-fold higher likelihood of recurrence than those tumours that weigh less.
authors.affiliation: Department of Urology, Hospital Universitario Fundación Alcorcón, Madrid, Spain.
authors.forename: Enrique
authors.initials: E
authors.lastname: De La Peña
authors.forename: Virginia
authors.initials: V
authors.lastname: Hernández
authors.forename: Cristina
authors.initials: C
authors.lastname: Blázquez
authors.forename: Maria D
authors.initials: MD
authors.lastname: Martin
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Díaz
authors.forename: Carlos
authors.initials: C
authors.lastname: Capitán
authors.forename: Isabel
authors.initials: I
authors.lastname: Alemany
authors.forename: Carlos
authors.initials: C
authors.lastname: Llorente
mesh_terms: D000368:Aged; D015653:Cystectomy / Q000379:methods*; D003558:Cystoscopy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000453:epidemiology; D009929:Organ Size; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D001743:Urinary Bladder / Q000473:pathology* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000601:surgery