title: An experience of single centre at C S M Medical University, Lucknow, for the prevalence of hemophilia in Uttar Pradesh.
abstract: OBJECTIVE
  To evaluate the incidence of hereditary bleeding disorders, registered at our centre from all over Uttar Pradesh over an extended period of 10 years.
  
  
  METHODS
  A complete coagulation profile of 240 cases conducted, followed by clinical history of the patient. The frequency and type of bleeding, age of onset, treatment taken, consanguinity and the blood transfusion if any, are little information collected from the patient.
  
  
  RESULTS
  The complete scenario of bleeders indicated maximum number (92%) of hemophilia 'A' from northern UP as compared from other zones (76.5% ± 3). Contrarily, hemophilia 'B' registered maximum from eastern zone (26%) and minimum from the northern zone (8%). The age diversity at diagnosis ranged between 1-32 years. The reasons for difference are all speculative. Definite cause needs extensive research.
  
  
  CONCLUSIONS
  The study showed that elderly patients with hemophilia had significantly more impairments in physical functioning and depression than younger ones.
authors.affiliation: Department of Pathology, C S M Medical University, Lucknow (UP)-, 226 003 India.
authors.forename: Kusum Lata
authors.initials: KL
authors.lastname: Mishra
authors.forename: Ashutosh
authors.initials: A
authors.lastname: Kumar
authors.forename: Ashish
authors.initials: A
authors.lastname: Gupta
keywords: Hemophilia; India; Prevalence; Uttar Pradesh