title: Reliability of reconstructed breast flap after chemotherapy and radiotherapy in immediate breast reconstruction.
abstract: BACKGROUND
  Postmastectomy adjuvant therapy is used to prevent locoregional recurrence and improve overall breast cancer specific survival rates. However, it can adversely affect the cosmetic results of reconstruction. Therefore, the authors examined flap stability and patients' satisfaction with immediate breast reconstruction after adjuvant therapy.
  
  
  METHODS
  We retrospectively reviewed the medical records of 204 patients from January 2006 to November 2011. For complication rates, the authors categorized the patients who underwent the immediate breast reconstruction into 4 groups: adjuvant chemotherapy and radiotherapy group, adjuvant chemotherapy only group, adjuvant radiotherapy only group, and the group that did not undergo adjuvant therapy. For comparison of patients' satisfaction, the study was performed with an additional 16 patients who had undergone delayed breast reconstruction.
  
  
  RESULTS
  Regarding complication rates, the group that had undergone adjuvant therapy showed no significant difference compared to the group that did not undergo adjuvant therapy. In evaluating the patients' satisfaction, there was no significant difference.
  
  
  CONCLUSIONS
  Even after adjuvant therapy, immediate breast reconstruction showed good results with respect to flap stability and patients' satisfaction. Immediate breast reconstruction and adjuvant therapy is a safe and useful option for breast cancer patients.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine, Busan, Korea.
authors.forename: Keun-Cheol
authors.initials: KC
authors.lastname: Lee
authors.forename: Tae-Heon
authors.initials: TH
authors.lastname: Kim
authors.forename: Su-Seong
authors.initials: SS
authors.lastname: Park
authors.forename: Min-Su
authors.initials: MS
authors.lastname: Kim
authors.forename: Myung-Hoon
authors.initials: MH
authors.lastname: Kim
authors.forename: Seok-Kwun
authors.initials: SK
authors.lastname: Kim
authors.forename: Se-Heon
authors.initials: SH
authors.lastname: Cho
authors.forename: Mi-Ri
authors.initials: MR
authors.lastname: Lee
authors.forename: Jin-Hwa
authors.initials: JH
authors.lastname: Lee
authors.forename: Hyung-Sik
authors.initials: HS
authors.lastname: Lee
authors.forename: Dae-Cheol
authors.initials: DC
authors.lastname: Kim
keywords: Breast; Drug therapy; Radiotherapy; Surgical flaps