title: [Mechanism of weightlessness osteoporosis and preventive and therapeutic effect of traditional Chinese medicine].
abstract: Weightlessness environment can lead to the muscle atrophy and body fluid distribution upward,which can cause the bone calcium metabolism disorder and always accompanied by the loss of bone microstructure and increased rate of bone fracture. Under microgravity,the astronauts are much easier to decrease the Ca2+ ion in bone, which can cause serious osteoporosis. However the bone lost is not equilibrium, it is especially serious in the mechanism loading bone and the recovery process is more difficult. These are very different from the osteoporosis in older people and postmenopausal osteoporosis. It is necessary to find an optimal method to due with it. In traditional Chinese medicine theory,the kidney stores "Jing" and dominates the bone, thus a lot of bone related diseases can be treated through the kidney. A lot of clinical practices have also proved that the Chinese herbs used under the guidance of basic Chinese medicine theory are always good at the treatment of common osteoporosis. In simulated weightlessness experiment, people found that the kidney nourishment drugs do can prevent the decrease of BMD. So in this article we want to review the causes of weightlessness and the potentials applications of tradition Chinese medicine in the treatment of weightlessness osteoporosis.
authors.affiliation: Beijing University of Traditional Chinese Medicine, Beijing 100029, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Zhu
authors.forename: Hua
authors.initials: H
authors.lastname: Guo
authors.forename: Xi-Juan
authors.initials: XJ
authors.lastname: Hao
authors.forename: Qian
authors.initials: Q
authors.lastname: Fu
authors.forename: Su-Min
authors.initials: SM
authors.lastname: Hu
mesh_terms: D006801:Humans; D055595:Mechanical Phenomena; D008516:Medicine, Chinese Traditional / Q000379:methods*; D010024:Osteoporosis / Q000209:etiology / Q000517:prevention & control* / Q000628:therapy*; D014893:Weightlessness / Q000009:adverse effects*