title: Percutaneous radiofrequency ablation guided by contrast-enhanced ultrasound in treatment of metastatic hepatocellular carcinoma after liver transplantation.
abstract: This study evaluated the advantages and applications of contrast-enhanced ultrasound (CEUS)-supported percutaneous radiofrequency ablation (RFA) in the treatment of metastatic hepatocellular carcinoma after liver transplantation, based on clinical details. CEUS-supported percutaneous RFA was adopted to treat 12 patients with hepatic metastatic carcinomas after liver transplantation. The diameters of the metastatic carcinomas varied from 1 cm to 5 cm, and the foci were discovered after 3 months to 12 months. Each focus was diagnosed and localised by CEUS for RFA once or twice. Curative effects were evaluated by CEUS or contrast-enhanced CT after the treatment. The re-examination results at 2 weeks post-treatment showed that the foci of 11 patients were ablated completely, whereas one patient with the largest focus required retreatment by RFA because of a partial residue. No local recurrence was found one month later in the re-examination. CEUS-supported percutaneous RFA in the treatment of hepatic metastatic carcinoma after liver transplantation has the advantages of accurate localisation, good efficacy, easy operation, and minimal invasion without any complications. Therefore, it can be recommended as the preferred therapy for hepatic metastatic carcinoma after liver transplantation.
authors.affiliation: The First Department of Hepatobiliary Surgery, Organ Transplantation Center for Army, 309th Hospital of Chinese PLA, Beijing, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Dai
authors.forename: Hong-Qiang
authors.initials: HQ
authors.lastname: Zhao
authors.forename: Run-Hao
authors.initials: RH
authors.lastname: Liu
authors.forename: Chang-Tao
authors.initials: CT
authors.lastname: Xu
authors.forename: Fang
authors.initials: F
authors.lastname: Zheng
authors.forename: Li-Bao
authors.initials: LB
authors.lastname: Yu
authors.forename: Wei-Min
authors.initials: WM
authors.lastname: Li
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000209:etiology / Q000556:secondary / Q000601:surgery*; D017115:Catheter Ablation; D003287:Contrast Media; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D025321:Surgery, Computer-Assisted; D018084:Ultrasonography, Interventional
chemical_list: D003287:Contrast Media