title: [MRI-guided targeted prostate biopsies in the diagnosis of prostate cancer: a systematic literature review].
abstract: BACKGROUND
  Advances in MRI technology for detection of prostate cancer allow targeted biopsies of suspicious areas.
  
  
  METHODS
  A systematic literature review was performed on Medline(®) with the keywords "targeted", "prostate biopsy" and related articles. We studied 65 abstracts and 102 related abstracts, read 38 articles and selected 27 articles.
  
  
  RESULTS
  Mental reconstruction gives way for targeted biopsies by direct MRI guidance inside the MRI, and MRI-TRUS fusion. The first option offers high precision targeting but is limited by the accessibility, cost and duration of the procedure. MRI-TRUS image fusion is a promising compromise. Cancer detection rates vary from 15 to 64 %.
  
  
  CONCLUSIONS
  Biopsies targeting suspicious areas on MRI are promising to improve the sensitivity and performance of prostate biopsies.
authors.affiliation: Service d'urologie, CHU de Grenoble, Grenoble cedex, France. gfiard@chu-grenoble.fr
authors.forename: G
authors.initials: G
authors.lastname: Fiard
authors.forename: J-L
authors.initials: JL
authors.lastname: Descotes
authors.forename: J-J
authors.initials: JJ
authors.lastname: Rambeaud
authors.forename: N
authors.initials: N
authors.lastname: Hohn
authors.forename: J
authors.initials: J
authors.lastname: Troccaz
authors.forename: J-A
authors.initials: JA
authors.lastname: Long
mesh_terms: D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods; D008279:Magnetic Resonance Imaging; D008297:Male; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*