title: Autologous gastrointestinal reconstruction: review of the optimal nontransplant surgical options for adults and children with short bowel syndrome.
abstract: Short bowel syndrome (SBS) results in loss of absorptive capacity of the development of gut, leading to malabsorption due to protein, energy, fluid, and electrolyte loss and imbalance while on enteral diet alone. Various nonsurgical and surgical therapeutic options that have emerged improve the survival outcome following SBS in both children and adults. An individualized, complex multidisciplinary approach to medical and surgical intestinal rehabilitation is needed to provide an opportunity for enteral autonomy to be possible in a patient with SBS. The remnant bowel plays a very pivotal role in autologous gastrointestinal reconstruction (AGIR) surgery. Intestinal transplantation, although promising and potentially life-saving for SBS, should be reserved for patients with failed AGIR or those who have no prospect for autologous enteral autonomy. This article reviews the evolution of nontransplant surgical management of patients with SBS.
authors.affiliation: Duke University Medical Center, Durham, NC, USA.
authors.forename: Aparna S
authors.initials: AS
authors.lastname: Rege
authors.forename: Debra Lynn
authors.initials: DL
authors.lastname: Sudan
mesh_terms: D000222:Adaptation, Physiological; D000328:Adult; D002648:Child; D013505:Digestive System Surgical Procedures / Q000379:methods; D041981:Gastrointestinal Tract / Q000601:surgery*; D006801:Humans; D007422:Intestines / Q000637:transplantation; D010288:Parenteral Nutrition / Q000379:methods; D019651:Plastic Surgery Procedures / Q000379:methods*; D012778:Short Bowel Syndrome / Q000601:surgery*; D014180:Transplantation