title: Bacterial pathogens of ventilator associated pneumonia in a tertiary referral hospital.
abstract: BACKGROUND
  This study evaluates the bacterial pathogens of Ventilator-associated pneumonia (VAP) in a tertiary referral hospital.
  
  
  METHODS
  A total of 109 bacterial pathogens from 91 adult patients with VAP, who were admitted to the medical intensive care unit from January 2008 to December 2009, were examined. Clinical characteristics, bacterial pathogens, and resistance profiles were analyzed.
  
  
  RESULTS
  Staphylococcus aureus (44%) was the most frequently isolated. Acinetobacter baumanii (30%), Pseudomonas aeruginosa (12%), Stenotrophomonas maltophilia (7%), Klebsiella pneumoniae (6%), and Serratia marcescens (2%) were isolated from the transtracheal aspirates or bronchoalveolar lavage in patients with VAP. There was no significant difference of bacterial pathogens between early and late onset VAP. All isolated S. aureus were methicillin resistant S. aureus; the imipenem resistance rate of A. baumanii was 69%.
  
  
  CONCLUSIONS
  The two most frequent pathogens of VAP were S. aureus and A. baumanii. There were no pathogenic differences between early and late onset VAP.
authors.affiliation: Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
authors.forename: Su Young
authors.initials: SY
authors.lastname: Chi
authors.forename: Tae Ok
authors.initials: TO
authors.lastname: Kim
authors.forename: Chan Woo
authors.initials: CW
authors.lastname: Park
authors.forename: Jin Yeong
authors.initials: JY
authors.lastname: Yu
authors.forename: Boram
authors.initials: B
authors.lastname: Lee
authors.forename: Ho Sung
authors.initials: HS
authors.lastname: Lee
authors.forename: Yu Il
authors.initials: YI
authors.lastname: Kim
authors.forename: Sung Chul
authors.initials: SC
authors.lastname: Lim
authors.forename: Yong Soo
authors.initials: YS
authors.lastname: Kwon
keywords: Acinetobacter baumanii; Pneumonia, Ventilator Associated; Staphylococcus aureus