title: Meningoencephalitis due to Listeria monocytogenes in a pregnant rhesus macaque (Macaca mulatta).
abstract: We here report a spontaneous case of meningoencephalitis due to Listeria monocytogenes in an adult primiparous rhesus macaque (Macaca mulatta) during an outbreak of listeriosis in an outdoor enclosure. Clinical signs included tremors, abnormal posture, and altered mental  status. Hematology and analyses of cerebrospinal fluid were consistent with bacterial infection. Pure cultures of L. monocytogenes were recovered from the placenta-abortus, cerebrospinal fluid, and brain tissue. The macaque did not respond to treatment and was euthanized. Histopathologic  examination of the brain revealed acute meningoencephalitis. This case represents an unusual clinical and pathologic presentation of listeriosis in a nonhuman primate in which the dam and fetus both were affected.
authors.affiliation: Department of Primate Medicine, California National Primate Center, University of California, Davis, California, USA. mjlemoy@primate.ucdavis.edu
authors.forename: Marie-Josee M F
authors.initials: MJ
authors.lastname: Lemoy
authors.forename: Danielle A
authors.initials: DA
authors.lastname: Lopes
authors.forename: J Rachel
authors.initials: JR
authors.lastname: Reader
authors.forename: Diccon R
authors.initials: DR
authors.lastname: Westworth
authors.forename: Ross P
authors.initials: RP
authors.lastname: Tarara
mesh_terms: D000818:Animals; D001921:Brain / Q000382:microbiology; D002555:Cerebrospinal Fluid / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D005313:Fetal Death / Q000382:microbiology / Q000662:veterinary*; D006652:Histological Techniques; D008089:Listeria monocytogenes / Q000302:isolation & purification*; D008253:Macaca mulatta; D008584:Meningitis, Listeria / Q000473:pathology / Q000662:veterinary*; D008992:Monkey Diseases / Q000382:microbiology* / Q000473:pathology*; D011247:Pregnancy