title: Investigate the Role of Glutathione S Transferase (GST) Polymorphism in Development of Hypertension in UAE Population.
abstract: BACKGROUND
  GST is a family of enzymes that are important in protection of the body against oxidative stress.
  
  
  OBJECTIVE
  Investigate the association between GSTT1 and GSTM1 polymorphism and hypertension.
  
  
  METHODS
  GSTT1 and GSTM1 genotypes were detected by PCR. The fragments were then analyzed by agarose gel electrophoresis.
  
  
  RESULTS
  There is no significant association between GSTT1 & GSTM1 polymorphism and hypertension (OR = 2.4, P > 0.05 and OR = 1.6, P > 0.05)
  
  
  CONCLUSIONS
  GSTT1 & GSTM1 polymorphism can be considered a risk factor for hypertension.
authors.affiliation: Rashid Hospital, Dubai Health Authority, Dubai, United Arab Emirates.
authors.forename: Kosar
authors.initials: K
authors.lastname: Hussain
authors.forename: Neveen
authors.initials: N
authors.lastname: Salah
authors.forename: Sahar
authors.initials: S
authors.lastname: Hussain
authors.forename: Sara
authors.initials: S
authors.lastname: Hussain
keywords: Glutathione S-Transferase T1; Hypertension; Polymorphism, Genetic