title: Diffusion tensor imaging of traumatic brain injury review: implications for neurorehabilitation.
abstract: Diffusion tensor imaging (DTI) has widely been used to investigate the microstructural damage of white matter tracts that occur in individuals with traumatic brain injury (TBI). In the current review, we discuss the white matter regions which are commonly affected in adults with TBI. We also describe the current literature that has utilized DTI to investigate the relationship between microstructural integrity with neuropsychological performance and clinical outcome measures. Finally, a model is presented of the potential utilization of DTI as a biomarker of efficacy in neurorehabilitation for individuals with TBI.
authors.affiliation: Department of Occupational Therapy, Steinhardt School of Culture, Education, and Human Development, New York University, New York, 10012, USA. gv23@nyu.edu
authors.forename: Gerald T
authors.initials: GT
authors.lastname: Voelbel
authors.forename: Helen M
authors.initials: HM
authors.lastname: Genova
authors.forename: Nancy D
authors.initials: ND
authors.lastname: Chiaravalotti
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Hoptman
mesh_terms: D001288:Attention; D001921:Brain / Q000473:pathology*; D001930:Brain Injuries / Q000150:complications / Q000175:diagnosis* / Q000534:rehabilitation; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology / Q000534:rehabilitation; D015928:Cognitive Behavioral Therapy; D056324:Diffusion Tensor Imaging; D056344:Executive Function; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008569:Memory Disorders / Q000175:diagnosis / Q000209:etiology / Q000534:rehabilitation; D008570:Memory, Short-Term; D009413:Nerve Fibers, Myelinated / Q000473:pathology; D011597:Psychomotor Performance