title: Mortality after acute myocardial infarction: significance of cardiovascular diabetic autonomic neuropathy (CDAN).
abstract: The aim of this study was to compare intrahospital and long-term mortalities after more than 10 years of the follow up after the first acute myocardial infarction (AMI) with patients with and without CDAN and without diabetes mellitus (DM).
  
  
  METHODS
  The study was based on 76 (43 men and 33 women) with DM type 2, CDAN was detected in 51 patients, and 374 (295 men and 79 women) without DM consecutively hospitalized with the first-ever AMI from January 1998. to December 2000. in Clinical Center of Montenegro Podgorica. Patients were followed until December 31. 2011. CDAN was searched for by standardized five tests evaluating heart rate and blood pressure variations.
  
  
  RESULTS
  Intrahospital mortality was presented in 10.53% diabetic patients and 5.61% nondiabetic patients, this difference is significant (p = 0.048). Long-term mortality was presented at 24 (82.75%) patients with CDAN and 5 (17.25%) patients without CDAN (p = 0.029). Long-term mortality rate was significantly higher in diabetic patients 29 (42.64%) than in nondiabetic patients 102 (30.72%) (p = 0.012).
  
  
  CONCLUSIONS
  Intrahospital mortality was significantly higher in diabetic than in nondiabetic patients. Identically the mortality after more than 10 years of the follow up after the first AMI was significantly higher in diabetic with, than in diabetic patients without CDAN, as in diabetic than in nondiabetic patients.
authors.affiliation: Department of Endocrinology and Cardiology, Clinical Center of Montenegro, Podgorica, Montenegro. vujosevics@t-com.me
authors.forename: Snezana
authors.initials: S
authors.lastname: Vujosevic
authors.forename: Miroslava
authors.initials: M
authors.lastname: Zamaklar
authors.forename: Natasa
authors.initials: N
authors.lastname: Belada
authors.forename: Sinisa
authors.initials: S
authors.lastname: Stamatovic
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D003929:Diabetic Neuropathies / Q000150:complications*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology / Q000401:mortality*