title: Structure and thermodynamics of Drug-RNA aptamer interactions.
abstract: This mini-review will provide an overview on the recent studies of structure and thermodynamics of RNA aptamers that target drug molecules. These aptamers are studied to provide insight into RNA drug interactions. This interaction is important due to the many roles RNA plays in cell biology.
authors.affiliation: University of Waterloo, Department of Chemistry, 200 University Ave West, Waterloo, ON, Canada.
authors.forename: J B
authors.initials: JB
authors.lastname: Da Costa
authors.forename: T
authors.initials: T
authors.lastname: Dieckmann
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000378:metabolism; D052157:Aptamers, Nucleotide / Q000737:chemistry* / Q000378:metabolism; D006678:HIV / Q000235:genetics / Q000378:metabolism; D016325:HIV Long Terminal Repeat / Q000235:genetics; D006801:Humans; D009690:Nucleic Acid Conformation; D009841:Oligonucleotides / Q000737:chemistry; D012313:RNA / Q000737:chemistry / Q000378:metabolism; D013816:Thermodynamics; D014764:Viral Proteins / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D052157:Aptamers, Nucleotide; D009841:Oligonucleotides; D014764:Viral Proteins; D012313:RNA