title: Growth and growth hormone treatment in children with chronic diseases.
abstract: Growth hormone has been available for treatment of various conditions for over 50 years. There have been a number of chronic disease states in which it has been used, such as chronic kidney disease, which became a US Food and Drug Administration (FDA)-approved indication in 1993. For other chronic disease states there have been clinical studies supporting its use, but they have not yet been approved as a indications by the FDA. Examples of such diseases are cystic fibrosis, chronic arthritis, short bowel syndrome, burn trauma, and hypophosphatemic rickets.
authors.affiliation: Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, AR 72202-3591, USA. MoralesAlba@uams.edu
authors.forename: Alba Morales
authors.initials: AM
authors.lastname: Pozzo
authors.forename: Stephen F
authors.initials: SF
authors.lastname: Kemp
mesh_terms: D001827:Body Height / Q000187:drug effects*; D002056:Burns / Q000150:complications; D002648:Child; D002908:Chronic Disease / Q000188:drug therapy*; D003550:Cystic Fibrosis / Q000188:drug therapy; D053098:Familial Hypophosphatemic Rickets / Q000150:complications; D005938:Glucocorticoids / Q000009:adverse effects; D006130:Growth Disorders / Q000188:drug therapy / Q000209:etiology; D013006:Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D007249:Inflammation / Q000150:complications; D011994:Recombinant Proteins / Q000627:therapeutic use; D051436:Renal Insufficiency, Chronic / Q000150:complications; D012778:Short Bowel Syndrome / Q000150:complications; D017086:beta-Thalassemia / Q000150:complications
chemical_list: D005938:Glucocorticoids; D011994:Recombinant Proteins; D013006:Growth Hormone