title: [Efficacy of ACE-inhibitors in patients with recent myocardial infarction. Studies with zofenopril].
abstract: Several large-scale trials have demonstrated improved survival with the administration of ACE-inhibitors to patients with a recent myocardial infarction. Many ACE-inhibitors with different pharmacological properties have been shown to be safe and effective. More recently the data provided by the Survival of Myocardial Infarction Long-term Evaluation (SMILE) program indicate that zofenopril may favorably affect the prognosis of patients with a recent myocardial infarction and, according to the results of the SMILE-4 study, it may be superior to ramipril with respect to some variables (cardiovascular hospitalizations) when both these ACE-inhibitors are administered combined with acetylsalicylic acid.
authors.affiliation: Universita degli Studi e Spedali Civili, Brescia. lombardi.carlo@alice.it
authors.forename: Carlo
authors.initials: C
authors.lastname: Lombardi
authors.forename: Anna Isotta
authors.initials: AI
authors.lastname: Castrini
authors.forename: Marco
authors.initials: M
authors.lastname: Metra
authors.forename: Valentina
authors.initials: V
authors.lastname: Carubelli
authors.forename: Valentina
authors.initials: V
authors.lastname: Lazzarini
authors.forename: Lorenza
authors.initials: L
authors.lastname: Inama
authors.forename: Livio
authors.initials: L
authors.lastname: Dei Cas
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D002216:Captopril / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy*; D013997:Time Factors
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; C044958:zofenopril; D002216:Captopril