title: C(sp(3))-F reductive elimination from alkylgold(iii) fluoride complexes.
abstract: Rare examples of C(sp(3))-F reductive elimination were observed from several cis-F(2)Au(R)(IPr) intermediates generated by oxidation of (IPr)AuR complexes with XeF(2). For R groups bearing β-hydrogens, β-hydride elimination was competitive with C(sp(3))-F reductive elimination. For strained cyclic R groups and most acyclic R groups lacking β-hydrogens, carbocation-like rearrangements occurred prior to C(sp(3))-F reductive elimination. Kinetics of the decay of one cis-F(2)Au(R)(IPr) species, stereochemical analysis of reductive elimination with a chiral R group, and DFT analysis collectively suggest C(sp(3))-F reductive elimination proceeding through transient cationic [(IPr)Au(F)(R)](+) intermediates with significant ionization of the Au-alkyl bonds.
authors.affiliation: Department of Chemistry, University of California-Berkeley, Berkeley, CA, 94720, USA.
authors.forename: Neal P
authors.initials: NP
authors.lastname: Mankad
authors.forename: F Dean
authors.initials: FD
authors.lastname: Toste