title: Comparison of visual results with accommodating intraocular lenses versus mini-monovision with a monofocal intraocular lens.
abstract: OBJECTIVE
  To compare near vision and quality of vision after controlling for pseudoaccommodation in patients with single-optic accommodating intraocular lenses (IOLs) or monofocal IOLs targeted for mini-monovision.
  
  
  METHODS
  Clinical practice.
  
  
  METHODS
  Prospective randomized controlled clinical trial.
  
  
  METHODS
  Patients were randomized to bilateral implantation of the Crystalens HD silicone accommodating IOL, the Tetraflex acrylic accommodating IOL, or the Tecnis 1-piece monofocal (nonaccommodating) control IOL. The target refraction for the control group was mini-monovision (-0.25 diopter [D] and -0.75 D). In the accommodating IOL groups, manufacturer recommendations were followed; that is, a target refraction of mini-monovision (-0.25 D and -0.75 D) in the acrylic accommodating group and +0.25 D in the silicone accommodating group. Pupil size and anterior corneal spherical aberration were measured preoperatively. Main outcome measures were binocular target refraction corrected near vision and contrast sensitivity 3 months postoperatively.
  
  
  RESULTS
  There were no statistically significant differences between the 3 groups in age, photopic or mesopic pupil size, anterior corneal spherical aberration, corneal astigmatism, or the power of the IOLs implanted. Binocular distance visual acuity at 4 m was 20/20(-) in all groups, intermediate vision was approximately 20/25, and near vision was 20/40 to 20/50. There were no statistically significant differences between the 3 groups in visual acuity or contrast sensitivity.
  
  
  CONCLUSIONS
  Single-optic accommodating IOLs did not offer a significant advantage in near visual acuity over mini-monovision with a monofocal (nonaccommodating) IOL.
authors.affiliation: From McMaster University, Hamilton, Ontario, Canada. Electronic address: georgebeiko@hotmail.com.
authors.forename: George H H
authors.initials: GHH
authors.lastname: Beiko
mesh_terms: D000065:Accommodation, Ocular / Q000502:physiology*; D000368:Aged; D057108:Corneal Wavefront Aberration / Q000175:diagnosis; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D011446:Prospective Studies; D011474:Prosthesis Design; D019591:Pseudophakia / Q000503:physiopathology*; D011680:Pupil / Q000502:physiology; D012029:Refraction, Ocular / Q000502:physiology*; D015348:Vision, Binocular / Q000502:physiology; D014792:Visual Acuity / Q000502:physiology*