title: Synthesis of oxazoles from enamides via phenyliodine diacetate-mediated intramolecular oxidative cyclization.
abstract: A group of functionalized oxazoles were synthesized in moderate to good yields from enamides via phenyliodine diacetate (PIDA)-mediated intramolecular cyclization. The main advantageous features of the present method include its broad substrate scope and the heavy-metal-free characteristic of the oxidative carbon-oxygen bond formation process.
authors.affiliation: Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
authors.forename: Yunhui
authors.initials: Y
authors.lastname: Zheng
authors.forename: Xuming
authors.initials: X
authors.lastname: Li
authors.forename: Chengfeng
authors.initials: C
authors.lastname: Ren
authors.forename: Daisy
authors.initials: D
authors.lastname: Zhang-Negrerie
authors.forename: Yunfei
authors.initials: Y
authors.lastname: Du
authors.forename: Kang
authors.initials: K
authors.lastname: Zhao
mesh_terms: D000085:Acetates / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007462:Iodobenzenes / Q000737:chemistry*; D015394:Molecular Structure; D010080:Oxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction
chemical_list: D000085:Acetates; D007462:Iodobenzenes; D010080:Oxazoles