title: Surgical outcome of spinal cord hemangioblastomas.
abstract: OBJECTIVE
  Spinal cord hemangioblastomas are rare tumors. Despite their benign, slow-growing nature, they can cause severe neurological consequences. The purpose of this study was to evaluate variable factors, including clinical features, tumor findings, the extent of resection, and its recurrence or progression, which determine postoperative functional outcomes.
  
  
  METHODS
  This study included sixteen patients at our institute who underwent microsurgical resection for sporadic spinal intramedullary hemangioblastomas and spinal intramedullary hemangioblastomas associated with von Hippel-Lindau (VHL) disease, between June 2003 and March 2012.
  
  
  RESULTS
  A total of 30 operations were performed. Total resection (TR) of the tumor was achieved in 10 patients, and subtotal resection (STR) was achieved in 6. Postoperatively, the initial presenting symptoms were improved in 18.7% of the patients and were unchanged in 56.3%, but 25% were worse. Stable postoperative neurological functions were found in 83% of patients with preoperative McCormick grade I, and TR was achieved in 75% of these patients. In the STR group, poorer neurological status was observed in one patient, despite multiple operations. There were no poorer outcomes in the four cases of VHL disease. Various factors were analyzed, but only a correlation between the pre- and postoperative neurological status was verified in the TR-group patients.
  
  
  CONCLUSIONS
  Preoperative focal neurological impairment and meticulous microsurgical manipulation may be predictors of favorable outcomes for solitary hemangioblastomas. In addition, the preservation of function is more important than the extent of resection in VHL disease.
authors.affiliation: Department of Neurosurgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Chang Hyun
authors.initials: CH
authors.lastname: Park
authors.forename: Chang-Hyun
authors.initials: CH
authors.lastname: Lee
authors.forename: Seung Jae
authors.initials: SJ
authors.lastname: Hyun
authors.forename: Tae-Ahn
authors.initials: TA
authors.lastname: Jahng
authors.forename: Hyun-Jib
authors.initials: HJ
authors.lastname: Kim
authors.forename: Ki-Jeong
authors.initials: KJ
authors.lastname: Kim
keywords: Functional outcome; Hemangioblastoma; Spinal cord; Von Hippel-Lindau disease