title: Cabergoline as treatment of ovarian hyperstimulation syndrome: a review.
abstract: One of the most serious complications of assisted reproduction techniques is ovarian hyperstimulation syndrome (OHSS). OHSS not only increases morbidity and mortality in IFV cycles, but also causes significant other problems, as cancelled in vitro fertilization (IVF) cycles, prolonged hospitalization, causing emotional and sociofinancial consequences. Several treatments for OHSS have been proposed and among these Cabergoline (Cb2). Despite the above-mentioned beneficial effect, Cb2 has not been widely used in everyday's clinical practice. With our study, we try to review all studies with strong evidence examining Cb2 use for OHSS prevention.
authors.affiliation: Second Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece. kalamp@yahoo.com
authors.forename: Theodoros
authors.initials: T
authors.lastname: Kalampokas
authors.forename: George
authors.initials: G
authors.lastname: Creatsas
authors.forename: Emmanouil
authors.initials: E
authors.lastname: Kalampokas
mesh_terms: D000077465:Cabergoline; D006063:Chorionic Gonadotropin / Q000009:adverse effects / Q000494:pharmacology; D018491:Dopamine Agonists / Q000009:adverse effects / Q000627:therapeutic use*; D004873:Ergolines / Q000009:adverse effects / Q000627:therapeutic use*; D019317:Evidence-Based Medicine; D005260:Female; D005300:Fertility Agents, Female / Q000009:adverse effects / Q000494:pharmacology; D005786:Gene Expression Regulation / Q000187:drug effects; D006801:Humans; D016471:Ovarian Hyperstimulation Syndrome / Q000188:drug therapy* / Q000378:metabolism / Q000517:prevention & control; D010053:Ovary / Q000187:drug effects* / Q000378:metabolism; D010766:Phosphorylation / Q000187:drug effects; D011499:Protein Processing, Post-Translational / Q000187:drug effects; D015398:Signal Transduction / Q000187:drug effects; D042461:Vascular Endothelial Growth Factor A / Q000096:biosynthesis / Q000235:genetics / Q000378:metabolism; D040301:Vascular Endothelial Growth Factor Receptor-2 / Q000096:biosynthesis / Q000235:genetics / Q000378:metabolism
chemical_list: D006063:Chorionic Gonadotropin; D018491:Dopamine Agonists; D004873:Ergolines; D005300:Fertility Agents, Female; C467484:VEGFA protein, human; D042461:Vascular Endothelial Growth Factor A; D040301:Vascular Endothelial Growth Factor Receptor-2; D000077465:Cabergoline