title: A biochemical study on variability of Superoxide dismutase, Catalase and Glutathione peroxidase in dry cleaners.
abstract: Several chemicals which induce cytotoxicity are broadly classified into three types and they are organophosphate, organochlorine and carbomate compounds. Perchloroethylene has been clearly identified as a carcinogen in experimental animals and it's a very common carcinogen used for dry clean purpose. Hence, in the present study, blood samples from dry cleaners were taken, Superoxide dismutase, Catalase and Glutathione peroxidase activity was estimated in blood samples of dry cleaners. There was a significant increase in the activity of Catalase, Glutathione Peroxidase, Superoxide Dismutase in dry cleaners of chronically exposed to perchloroethylene as compared to controls. The increased activities of antioxidant enzymes may be a compensatory regulation in response to increased oxidative stress induced by perchloroethylene.
authors.affiliation: Department of Biochemistry, Mohamed Sathak College of Arts and Science, Sholinganallur, Chennai, India.
authors.forename: S
authors.initials: S
authors.lastname: Anbhazhagan
authors.forename: Santosh S
authors.initials: SS
authors.lastname: Winkins
keywords: Antioxidant enzymes; Catalase; Dry cleaners; Glutathione Peroxidase; Perchloroethylene; Superoxide Dismutase