title: Age-related aspects of cutaneous wound healing: a mini-review.
abstract: As the aging population in developed countries is growing in both numbers and percentage, the medical, social, and economic burdens posed by nonhealing wounds are increasing. Hence, it is all the more important to understand the mechanisms underlying age-related impairments in wound healing. The purpose of this article is to give a concise overview of (1) normal wound healing, (2) alterations in aging skin that have an impact on wound repair, (3) alterations in the repair process of aged skin, and (4) general factors associated with old age that might impair wound healing, with a focus on the literature of the last 10 years.
authors.affiliation: Division of Experimental Pathophysiology and Immunology, Biocenter, Innsbruck Medical University, Innsbruck, Austria. roswitha.sgonc@i-med.ac.at
authors.forename: Roswitha
authors.initials: R
authors.lastname: Sgonc
authors.forename: Johann
authors.initials: J
authors.lastname: Gruber
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology*; D006801:Humans; D062326:Re-Epithelialization / Q000502:physiology; D012867:Skin / Q000293:injuries*; D015595:Skin Aging / Q000502:physiology; D014945:Wound Healing / Q000502:physiology*