title: Imaging diagnosis-cholangiocellular adenoma: contrast-enhanced ultrasonographic findings of a benign tumor mimicking malignant neoplasia in a dog.
abstract: A 9-year-old Giant Schnauzer was referred for polyuria and polydipsia. On abdominal ultrasound, a hyperechoic mass with low color Doppler signal was detected in the medial right hepatic lobe. Contrast-enhanced ultrasound (CEUS) demonstrated increased enhancement of the mass during the arterial phase, and contrast washout during portal and late phases with decreased enhancement relative to the liver. These findings were consistent with primary liver malignancy or liver metastasis. A final diagnosis of cholangiocellular adenoma was made based on histopathology. To our knowledge, this is the first description of a benign hepatic neoplasm exhibiting malignant CEUS characteristics in a dog.
authors.affiliation: Department of Veterinary Medical Science, University of Bologna, Bologna, Italy. alessia.diana@unibo.it
authors.forename: Marco
authors.initials: M
authors.lastname: Baron Toaldo
authors.forename: Alessia
authors.initials: A
authors.lastname: Diana
authors.forename: Giuliano
authors.initials: G
authors.lastname: Bettini
authors.forename: Pamela
authors.initials: P
authors.lastname: Di Donato
authors.forename: Nikolina
authors.initials: N
authors.lastname: Linta
authors.forename: Mario
authors.initials: M
authors.lastname: Cipone
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging*; D002759:Adenoma, Bile Duct / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D000818:Animals; D001650:Bile Duct Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D001653:Bile Ducts, Intrahepatic / Q000000981:diagnostic imaging / Q000473:pathology; D003287:Contrast Media; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000000981:diagnostic imaging*; D004285:Dogs; D005260:Female; D007089:Image Enhancement; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D010743:Phospholipids; D013459:Sulfur Hexafluoride; D014463:Ultrasonography / Q000662:veterinary; D018615:Ultrasonography, Doppler, Color / Q000662:veterinary
chemical_list: D003287:Contrast Media; D010743:Phospholipids; C420843:contrast agent BR1; D013459:Sulfur Hexafluoride