title: Prevalence and correlates of Kaposi's sarcoma-associated herpesvirus infection in a sample of men who have sex with men in Eastern China.
abstract: This study aimed to determine the seroprevalence of Kaposi’s sarcoma-associated herpesvirus(KSHV) and related factors in men who have sex with men (MSM) in China. A total of 208 subjects were recruited from eastern China from 2008 to 2009. Plasma samples were collected and screened for KSHV, HIV and syphilis. Overall, KSHV seroprevalence was 32.7% in the subjects. About 92.7% of subjects reported having ever had anal sex with a man, of whom 67.8% had receptive anal sex and 77.9% had insertive anal sex. About 93.1% of the study participants reported having had oral sex with a man, of whom 76.0% had receptive oral sex and 56.7% had insertive oral sex. KSHV seropositivity was independently associated with receptive anal sex[odds ratio (OR) 2.68, 95% confidence interval (CI) 1.15–6.23], syphilis (OR 3.25, 95% CI1.56–6.76) and HSV-2 infection (OR 2.40, 95% CI 1.09–5.26). KSHV infection is highly prevalent and is probably sexually transmitted among MSM in eastern China.
authors.affiliation: Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China.
authors.forename: T
authors.initials: T
authors.lastname: Zhang
authors.forename: H
authors.initials: H
authors.lastname: Lin
authors.forename: V
authors.initials: V
authors.lastname: Minhas
authors.forename: W
authors.initials: W
authors.lastname: Zhu
authors.forename: C
authors.initials: C
authors.lastname: Wood
authors.forename: N
authors.initials: N
authors.lastname: He
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D002681:China / Q000453:epidemiology; D005260:Female; D006566:Herpesviridae Infections / Q000175:diagnosis* / Q000453:epidemiology*; D019288:Herpesvirus 8, Human / Q000276:immunology*; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral