title: Conserved RNA motifs of EMCV IRES as potential building blocks to design RNA nanostructures.
abstract: The highly conserved secondary structural RNA motifs endowed by the IRES element of EMCV picornavirus provide an excellent platform to design RNA nanostructures for application in medicine. We have identified a 44mer RNA, hosting distinct 15mer and 11mer RNA stem loop motifs, as potential building blocks for the design of RNA nanostructures.
authors.affiliation: School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
authors.forename: Kwong Kit
authors.initials: KK
authors.lastname: Chan
authors.forename: Vasudevan
authors.initials: V
authors.lastname: Ramesh
mesh_terms: D001483:Base Sequence; D017124:Conserved Sequence; D004686:Encephalomyocarditis virus / Q000235:genetics*; D008969:Molecular Sequence Data; D049329:Nanostructures / Q000737:chemistry*; D059372:Nucleotide Motifs; D012367:RNA, Viral / Q000737:chemistry* / Q000235:genetics*
chemical_list: D012367:RNA, Viral