title: The BLADE-ON-PETIOLE genes of Arabidopsis are essential for resistance induced by methyl jasmonate.
abstract: BACKGROUND
  NPR1 is a gene of Arabidopsis thaliana required for the perception of salicylic acid. This perception triggers a defense response and negatively regulates the perception of jasmonates. Surprisingly, the application of methyl jasmonate also induces resistance, and NPR1 is also suspected to be relevant. Since an allelic series of npr1 was recently described, the behavior of these alleles was tested in response to methyl jasmonate.
  
  
  RESULTS
  The response to methyl jasmonate of different npr1s alleles and NPR1 paralogs null mutants was measured by the growth of a pathogen. We have also tested the subcellular localization of some npr1s, along with the protein-protein interactions that can be measured in yeast. The localization of the protein in npr1 alleles does not affect the response to methyl jasmonate. In fact, NPR1 is not required. The genes that are required in a redundant fashion are the BOPs. The BOPs are paralogs of NPR1, and they physically interact with the TGA family of transcription factors.
  
  
  CONCLUSIONS
  Some npr1 alleles have a phenotype in this response likely because they are affecting the interaction between BOPs and TGAs, and these two families of proteins are responsible for the resistance induced by methyl jasmonate in wild type plants.
authors.affiliation: Instituto de Biología Molecular y Celular de Plantas (IBMCP), Universidad Politécnica de Valencia (UPV)-Consejo Superior de Investigaciones Científicas (CSIC), Ciudad Politécnica de la Innovación (CPI), Valencia, Spain.
authors.forename: Juan Vicente
authors.initials: JV
authors.lastname: Canet
authors.forename: Albor
authors.initials: A
authors.lastname: Dobón
authors.forename: Jana
authors.initials: J
authors.lastname: Fajmonová
authors.forename: Pablo
authors.initials: P
authors.lastname: Tornero
mesh_terms: D000085:Acetates / Q000494:pharmacology*; D000483:Alleles; D017360:Arabidopsis / Q000235:genetics / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D003517:Cyclopentanes / Q000494:pharmacology*; D060467:Disease Resistance / Q000235:genetics; D018506:Gene Expression Regulation, Plant; D054883:Oxylipins / Q000494:pharmacology*; D010641:Phenotype; D030821:Plants, Genetically Modified / Q000235:genetics / Q000502:physiology
chemical_list: D000085:Acetates; D029681:Arabidopsis Proteins; C496963:BOP1 protein, Arabidopsis; C506721:BOP2 protein, Arabidopsis; D003517:Cyclopentanes; C105496:NPR1 protein, Arabidopsis; D054883:Oxylipins; C072239:methyl jasmonate