title: Clinicopathological spectrum of non-alcoholic fatty liver disease among patients in Kerala.
abstract: Non-alcoholic fatty liver disease and its more aggressive form, non-alcoholic steatohepatitis are entities that are becoming more and more interesting to the medical community in general. A total of 93 Non-alcoholic fatty liver disease patients (64 male and 29 female) within the age range between 28 to 63 years were studied. All of them showed elevated alanine aminotransferase level (104.07 ± 56.04). Aspartate aminotransferase level (58.13 ± 31.96) was elevated more than its normal level in 82% cases and AST to ALT ratio was found 0.59 ± 0.26. Predisposing factors were diabetes mellitus (37%), obesity (13%) and hyperlipidemia (41%). In addition, 32% of the subjects were overweight.18% of the patients had elevated serum bilirubin. Our findings recommend a lower cutoff value than suggested by the World Health Organization for overweight and obesity among this racial-ethnic group.
authors.affiliation: Department of Biochemistry, Amrita Institute of Medical Sciences, Elamakkara P.O. Cochin, 682 026 Kerala India  ; Department of Biochemistry, Agartala Govt. Medical College P.O. Kunjaban, Agartala, 799006 West Tripura India.
authors.forename: Subir Kumar
authors.initials: SK
authors.lastname: Das
authors.forename: Sukhes
authors.initials: S
authors.lastname: Mukherjee
authors.forename: Gaurav
authors.initials: G
authors.lastname: Pandey
authors.forename: V
authors.initials: V
authors.lastname: Balakrishnan
authors.forename: D M
authors.initials: DM
authors.lastname: Vasudevan
keywords: Body mass index; Diabetes mellitus; Hyperlipidemia; Non-alcoholic fatty liver disease; Obesity; Waist-to-hip ratio