title: Abdominal auras in patients with mesial temporal sclerosis.
abstract: To better clarify abdominal auras and their clinical correlates, we enrolled 331 temporal lobe epilepsy patients who received surgical treatment. Detailed descriptions of their auras were obtained before surgery and reconfirmed during postoperative outpatient follow-ups. Pathology revealed mesial temporal sclerosis (MTS) in 256 patients (77.3%) and 75 non-MTS. Of 214 MTS patients with auras, 78 (36.4%) reported abdominal auras (vs. 30.4% in non-MTS, p=0.439): 42 with left-sided seizure onset, and 36 with right-sided seizure onset. Moreover, 49 of the 78 MTS patients had abdominal auras accompanied by rising sensations (vs. 2 of 14 in non-MTS group, p=0.004). The "rising air" was initially described to locate to the epigastric (47.8%) or periumbilical area (45.7%) and mostly reached the chest (40.4%) or remained in the abdominal region (27.1%). An epigastric location of "rising air" favored a left-sided seizure onset, and non-epigastric areas favored right-sided seizure onset (p=0.018). Finally, we found that abdominal auras with or without rising sensations did not predict postoperative seizure outcomes.
authors.affiliation: Department of Neurology, The Neurological Institute, Taipei Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan.
authors.forename: Yi-Chun
authors.initials: YC
authors.lastname: Kuan
authors.forename: Yang-Hsin
authors.initials: YH
authors.lastname: Shih
authors.forename: Chien
authors.initials: C
authors.lastname: Chen
authors.forename: Hsiang-Yu
authors.initials: HY
authors.lastname: Yu
authors.forename: Chun-Hing
authors.initials: CH
authors.lastname: Yiu
authors.forename: Yung-Yung
authors.initials: YY
authors.lastname: Lin
authors.forename: Shang-Yeong
authors.initials: SY
authors.lastname: Kwan
authors.forename: Der-Jen
authors.initials: DJ
authors.lastname: Yen
mesh_terms: D000328:Adult; D038481:Anterior Temporal Lobectomy / Q000379:methods; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications* / Q000175:diagnosis / Q000209:etiology*; D004833:Epilepsy, Temporal Lobe / Q000150:complications* / Q000601:surgery; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D011183:Postoperative Complications; D012189:Retrospective Studies; D020886:Somatosensory Disorders / Q000150:complications* / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D055815:Young Adult