title: Correlation between serum lipid profile and carotid intima-media thickness in Polycystic Ovarian Syndrome.
abstract: Abnormal lipid profile is often found in women with Polycystic Ovary Syndrome. To assess the impact of abnormal lipid profile on atherosclerosis in young Polycystic Ovary Syndrome women, carotid intima-media thickness as judged by B-mode ultrasonography were done in 30 young (18-35 yrs) Polycystic Ovary Syndrome women and in similarly age-matched 30 apparently healthy controls. Compared to controls, young Polycystic Ovary Syndrome women had significantly elevated serum total cholesterol, triglyceride and LDL-C levels and carotid intima-media thickness. HDL-C level did not differ significantly between two groups of women. In Polycystic Ovary Syndrome women carotid intima-media thickness was positively correlated with serum total cholesterol, triglyceride and LDL-C and negatively correlated with serum HDL-C. Our study suggests that even young Polycystic Ovary Syndrome women are prone to atherosclerosis from early age.
authors.affiliation: Department of Biochemistry, Institute of Post Graduate Medical Education and Research, Kolkata, 700 020 W.B India.
authors.forename: Sarama
authors.initials: S
authors.lastname: Saha
authors.forename: Chandan
authors.initials: C
authors.lastname: Sarkar
authors.forename: Subhash Chandra
authors.initials: SC
authors.lastname: Biswas
authors.forename: R
authors.initials: R
authors.lastname: Karim
keywords: Carotid Intima-media thickness; Lipid Profile; Polycystic Ovary Syndrome