title: High genetic diversity and predominance of Rhinovirus A and C from Panamanian hospitalized children under five years with respiratory infections.
abstract: BACKGROUND
  Human Rhinoviruses (HRVs) have high genetic diversity and three species have been described: HRV-A, HRV-B, and the recently recognized HRV-C, which has been rapidly identified worldwide.
  
  
  RESULTS
  In the present study, we report the frequency and diversity of Human Rhinovirus (HRV) strains circulating in Panama from children hospitalized with respiratory infections.
  
  
  CONCLUSIONS
  HRVs of species A, B and C have been identified with a predominance of HRV-A and HRV-C over HRV-B, and marked genetic diversity within each species.
authors.affiliation: Instituto Conmemorativo Gorgas de Estudios de la Salud, Panama City, Panamá.
authors.forename: Danilo
authors.initials: D
authors.lastname: Franco
authors.forename: Adriana
authors.initials: A
authors.lastname: Delfraro
authors.forename: Leyda
authors.initials: L
authors.lastname: Abrego
authors.forename: Maria
authors.initials: M
authors.lastname: Cano
authors.forename: Celedonio
authors.initials: C
authors.lastname: Castillo
authors.forename: Marlene
authors.initials: M
authors.lastname: Castillo
authors.forename: Juan
authors.initials: J
authors.lastname: Castillo
authors.forename: Juan
authors.initials: J
authors.lastname: Pascale
authors.forename: Juan
authors.initials: J
authors.lastname: Arbiza
mesh_terms: D002673:Child, Hospitalized; D002675:Child, Preschool; D016000:Cluster Analysis; D005260:Female; D014644:Genetic Variation; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008969:Molecular Sequence Data; D010176:Panama / Q000453:epidemiology; D010802:Phylogeny; D010850:Picornaviridae Infections / Q000453:epidemiology / Q000821:virology*; D012367:RNA, Viral / Q000235:genetics; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000821:virology*; D012229:Rhinovirus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D017422:Sequence Analysis, DNA
chemical_list: D012367:RNA, Viral