title: Vitrectomy and panretinal photocoagulation reduces the occurrence of neovascular glaucoma in central retinal vein occlusion with vitreous hemorrhage.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the best-corrected visual acuity and occurrence of neovascular glaucoma with vitrectomy (VT) and panretinal photocoagulation or without VT in central retinal vein occlusion (CRVO) associated with vitreous hemorrhage (VH).
  
  
  METHODS
  The charts from patients diagnosed as having CRVO with VH at Chang Gung Memorial Hospital (Taiwan) were reviewed. They were grouped based on whether they also underwent VT. The main outcome measurements were the best-corrected visual acuity and incidence of neovascular glaucoma.
  
  
  RESULTS
  There were 83 eyes that had CRVO with VH from 83 patients (VT group, 56 eyes; non-VT group, 27 eyes). There was no significant difference between the VT and non-VT groups in terms of age, gender, diabetes, hypertension, lens status, and follow-up period. The non-VT group had a better best-corrected visual acuity (P = 0.018) and less VH (P = 0.025) than the VT group at baseline; however, the VT group had a better best-corrected visual acuity at the end of the follow-up than the non-VT group (P < 0.001). Most importantly, there was a higher neovascular glaucoma development (37%) in the non-VT group compared with that (14.3%) in the VT group (P = 0.025).
  
  
  CONCLUSIONS
  The visual outcomes of CRVO with VH are unfavorable whether VT was performed. However, VT and panretinal photocoagulation improved visual acuity and reduced the incidence of neovascular glaucoma in CRVO with VH.
authors.affiliation: Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan.
authors.forename: Lan-Hsin
authors.initials: LH
authors.lastname: Chuang
authors.forename: Nan-Kai
authors.initials: NK
authors.lastname: Wang
authors.forename: Yen-Po
authors.initials: YP
authors.lastname: Chen
authors.forename: Ling
authors.initials: L
authors.lastname: Yeung
authors.forename: Yih-Shiou
authors.initials: YS
authors.lastname: Hwang
authors.forename: Kuan-Jen
authors.initials: KJ
authors.lastname: Chen
authors.forename: Wei-Chi
authors.initials: WC
authors.lastname: Wu
authors.forename: Tun-Lu
authors.initials: TL
authors.lastname: Chen
authors.forename: Chi-Chun
authors.initials: CC
authors.lastname: Lai
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D015355:Glaucoma, Neovascular / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D006801:Humans; D017075:Laser Coagulation; D054023:Lasers, Semiconductor / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012170:Retinal Vein Occlusion / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy; D014823:Vitreous Hemorrhage / Q000150:complications / Q000503:physiopathology / Q000601:surgery*