title: High prevalence of vitamin D deficiency among newly diagnosed youth-onset diabetes mellitus in north India.
abstract: OBJECTIVE
  Vitamin D deficiency is common at all ages, and low levels of vitamin D have been associated with high incidence of type 1 diabetes. Similar results are not consistent for type 2 diabetes. The aim of the present study was to estimate vitamin D status in newly detected youth-onset diabetes in north India.
  
  
  METHODS
  This was a prospective case control study at a tertiary care hospital in north India. Seventy two newly detected youth-onset diabetes subjects (age < 25 years), and 41 age- and gender-matched healthy controls were studied. In addition to basic information and management regarding their diabetes, metabolic parameters and serum 25(OH)D were measured in both the groups.
  
  
  RESULTS
  Vitamin D deficiency was seen in 91.1% of the subjects with diabetes, and 58.5% of the healthy controls. Mean ±SD 25(OH)D was significantly low, 7.88 ± 1.20 ng/mL in subjects with diabetes against 16.64 ± 7.83 ng/mL in controls. Sixty percent of cases had severe Vitamin D deficiency compared with 8.3% in controls. Levels of vitamin D did not correlate with clinical parameters, such as gender, body mass index; or with biochemical parameters, such as serum calcium, phosphorus, alkaline phosphatase, fasting plasma glucose, and HbA1C.
  
  
  CONCLUSIONS
  Vitamin D deficiency is common in people with youth-onset diabetes.
authors.affiliation: Department of Endocrinology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, India.
authors.forename: Riyaz Ahmad
authors.initials: RA
authors.lastname: Daga
authors.forename: Bashir Ahmad
authors.initials: BA
authors.lastname: Laway
authors.forename: Zaffar Amin
authors.initials: ZA
authors.lastname: Shah
authors.forename: Shahnaz Ahmad
authors.initials: SA
authors.lastname: Mir
authors.forename: Suman Kumar
authors.initials: SK
authors.lastname: Kotwal
authors.forename: Abdul Hamid
authors.initials: AH
authors.lastname: Zargar
mesh_terms: D000293:Adolescent; D015992:Body Mass Index; D016022:Case-Control Studies; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D015995:Prevalence; D011446:Prospective Studies; D014808:Vitamin D Deficiency / Q000097:blood / Q000453:epidemiology*