title: The Davis-Beirut Reaction: a novel entry into 2H-indazoles and indazolones. Recent biological activity of indazoles.
abstract: A novel, easy method for the syntheses of richly diversified 2H-indazoles and indazolones, called the Davis-Beirut reaction, and other recent 2H-indazole synthetic routes are briefly reviewed. An update on the biological activity of indazoles is also surveyed.
authors.affiliation: Department of Chemistry, American University of Beirut, Beirut, Lebanon. haddadin@aub.edu.lb
authors.forename: Makhluf J
authors.initials: MJ
authors.lastname: Haddadin
authors.forename: Wayne E
authors.initials: WE
authors.lastname: Conrad
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Kurth
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry / Q000633:toxicity; D002318:Cardiovascular Diseases / Q000188:drug therapy; D049109:Cell Proliferation / Q000187:drug effects; D005306:Fertilization / Q000187:drug effects; D006801:Humans; D007191:Indazoles / Q000737:chemistry* / Q000627:therapeutic use / Q000633:toxicity; D007536:Isomerism; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D007191:Indazoles; D019001:Nitric Oxide Synthase