title: [Contemporary outlook on prevention and correction of early disturbances of carbohydrate metabolism in cardiological  practice].
abstract: In the search for effective means of prevention and detection of early markers of type 2 diabetes mellitus (DM) the scientists take an interest for early disturbances of carbohydrate metabolism. In this work we present data of international clinical studies confirming that early disturbances of carbohydrate metabolism appear to be an independent risk factor of cardiovascular diseases. In this connection possibilities of prevention and treatment of early disturbances of carbohydrate metabolism are discussed. We also present classification of antihyperglycemic drugs and analysis of their mechanism of action and efficacy from the point of view of evidence based medicine. The data presented evidence that successful primary prevention of type 2 DM at the stage of early disturbances of carbohydrate metabolism can facilitate lowering of cardiovascular complications.
authors.forename: M N
authors.initials: MN
authors.lastname: Mamedov
authors.forename: E A
authors.initials: EA
authors.lastname: Poddubskaia
authors.forename: M N
authors.initials: MN
authors.lastname: Kovrigina
authors.forename: Z O
authors.initials: ZO
authors.lastname: Ugurchieva
authors.forename: R T
authors.initials: RT
authors.lastname: Didigova
mesh_terms: D050260:Carbohydrate Metabolism / Q000187:drug effects*; D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000378:metabolism / Q000517:prevention & control; D061345:Early Medical Intervention / Q000379:methods; D019317:Evidence-Based Medicine / Q000379:methods; D006801:Humans; D007004:Hypoglycemic Agents / Q000145:classification / Q000494:pharmacology; D015980:Public Health Practice; D016032:Randomized Controlled Trials as Topic
chemical_list: D007004:Hypoglycemic Agents