title: Self-reported drug allergy in health care workers in conservative and surgical medicine departments.
abstract: BACKGROUND
  Drug allergy comprises 10% to 30% of all adverse drug reactions, and according to data from the literature, sensitivity to drug allergens is 2 to 3 times more common in health care workers than in the general population.
  
  
  OBJECTIVE
  The aims of this study were to estimate the prevalence of self-reported drug allergy in health care workers and compare the data obtained between doctors and nurses from conservative medicine (CM) and surgical medicine (SM) departments.
  
  
  METHODS
  This was an analytic questionnaire-based survey conducted using the European Network of Drug Allergy questionnaire adapted to the Lithuanian population. The questionnaires were completed by 346 individuals.
  
  
  RESULTS
  Nurses from SM departments reported allergy symptoms more frequently than doctors from the same departments (38.1% vs. 16.7%, P = .01) and nurses from the CM departments (38.1% vs. 18%; P = .02). The most common drugs reported to cause hypersensitivity symptoms were similar in the CM and SM departments: antibiotics (8.8% and 12.7%), local anesthetics (2.9% and 6.9%), and group B vitamins (1.2% and 2.1%). Skin damage was indicated as the most common clinical manifestation.
  
  
  CONCLUSIONS
  Based on the data reported by the questionnaire respondents, drug allergy was most prevalent among nurses from the SM departments, and antibiotics and local anesthetics were the most common substances that induced the symptoms.
authors.affiliation: Lithuanian University of Health Sciences, Medical Academy, Kaunas, Lithuania.
authors.forename: L
authors.initials: L
authors.lastname: Zilinskaite
authors.forename: D
authors.initials: D
authors.lastname: Tamasauskas
authors.forename: V
authors.initials: V
authors.lastname: Kvedariene
authors.forename: B
authors.initials: B
authors.lastname: Sitkauskiene
mesh_terms: D000328:Adult; D004342:Drug Hypersensitivity / Q000453:epidemiology*; D005260:Female; D006282:Health Personnel; D006801:Humans; D008297:Male; D008875:Middle Aged; D009726:Nurses; D015995:Prevalence; D013503:Surgery Department, Hospital; D011795:Surveys and Questionnaires