title: Effect of exercise on the expression of HSPBP1, PGLYRP1, and HSPA1A genes in human leukocytes.
abstract: The effects of 30-min medium-intensity exercise on the expression of genes encoding heat shock protein 70 (HSPA1A) and its cochaperones HSP-70-binding protein 1 (HSPBP1) and Tag7 (PGLYRP1) in human leukocytes were studied. Transcription activities of HSPA1A and PGLYRP1 genes increased immediately after medium-intensity exercise, while activity of HSPBP1 gene remained unchanged. During recovery after exercise, the expression of HSPA1A gene virtually did not change, while the expression of PGLYRP1 gene continued to increase and after 90 min more than 2-fold surpassed the basal level.
authors.affiliation: BioClinicum Center, Moscow, Russia.
authors.forename: D V
authors.initials: DV
authors.lastname: Maltseva
authors.forename: E A
authors.initials: EA
authors.lastname: Ryabenko
authors.forename: S V
authors.initials: SV
authors.lastname: Sizova
authors.forename: D V
authors.initials: DV
authors.lastname: Yashin
authors.forename: S A
authors.initials: SA
authors.lastname: Khaustova
authors.forename: M Yu
authors.initials: MY
authors.lastname: Shkurnikov
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics*; D000293:Adolescent; D015703:Antigens, CD / Q000235:genetics; D056352:Athletes; D016207:Cytokines / Q000235:genetics*; D015444:Exercise; D015870:Gene Expression; D018840:HSP70 Heat-Shock Proteins / Q000235:genetics*; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000166:cytology / Q000378:metabolism; D020411:Oligonucleotide Array Sequence Analysis; D055815:Young Adult
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D015703:Antigens, CD; D016207:Cytokines; D018840:HSP70 Heat-Shock Proteins; C490786:HSPA1A protein, human; C116331:HSPBP1 protein, human; C491878:PGLYRP1 protein, human