title: Gender-specific prevalence and associated risk factors of prehypertension among rural children and adolescents in Northeast China: a cross-sectional study.
abstract: Little is known about the prevalence and risk profile of prehypertension among Chinese children and adolescents. The aim of the present study was to investigate the prehypertensive status and its associated risk factors among rural Chinese children and adolescents. We conducted a cross-sectional study including 5,245 children and adolescents (2,732 boys and 2,513 girls) aged 5-18 years in Northeast China. Main anthropometric data and related information were collected. The overall prevalence of prehypertension and hypertension was 15 % and 20.2 %, respectively. The prevalence of prehypertension among boys was 15.7 %, compared to that of 14.2 % among girls (P = 0.256). After adjusting for age, race, weight status, waist circumference, triceps skinfold, family income, smoking and drinking status, boys aged 12-14 and 15-18 years had a 2.86- and 5.97-fold risk of prehypertension, respectively, compared to those aged 5-8 years. Overweight and obese boys had an increased risk of prehypertension in comparison to those with normal weight (overweight: odds ratio [OR] = 1.837, 95 % confidence interval [CI] 1.321-2.556; obese: OR = 2.941, 95 % CI 1.783-4.851). A larger triceps skinfold (≥90th percentile) was significantly related to increased odds of prehypertension (OR = 2.32; 95 % CI, 1.516-3.55) among boys. For girls, only older age was found to be a risk factor for prehypertension.
  
  
  CONCLUSIONS
  Pediatric prehypertension is highly prevalent in rural Northeast China. The risk factors for prehypertension differed among boys and girls. A more comprehensive risk profile of prehypertension among children and adolescents needs to be established for early prevention.
authors.affiliation: Department of Cardiology, the First Hospital of China Medical University, 155 Nanjing North Street, Shenyang, Heping District, 110001, China.
authors.forename: Xiaofan
authors.initials: X
authors.lastname: Guo
authors.forename: Liqiang
authors.initials: L
authors.lastname: Zheng
authors.forename: Yang
authors.initials: Y
authors.lastname: Li
authors.forename: Shasha
authors.initials: S
authors.lastname: Yu
authors.forename: Xinghu
authors.initials: X
authors.lastname: Zhou
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.forename: Xingang
authors.initials: X
authors.lastname: Zhang
authors.forename: Zhaoqing
authors.initials: Z
authors.lastname: Sun
authors.forename: Yingxian
authors.initials: Y
authors.lastname: Sun
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D058246:Prehypertension / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D012424:Rural Population / Q000706:statistics & numerical data; D012737:Sex Factors; D012885:Skinfold Thickness