title: Structural stabilization of DNA-templated nanostructures: crosslinking with 2,5-bis(2-thienyl)pyrrole monomers.
abstract: Ordered 2,5-bis(2-thienyl)pyrrole (SNS) zipper arrays are formed by hybridization of complementary DNA oligomers each containing covalently bound SNS monomers. Upon oxidation with HRP/H(2)O(2), these SNS arrays are converted to oligomers having specific lengths and conformation. As a consequence of this reaction the two SNS-containing strands are permanently crosslinked.
authors.affiliation: Georgia Institute of Technology, Atlanta, Georgia, USA.
authors.forename: Wen
authors.initials: W
authors.lastname: Chen
authors.forename: Gary B
authors.initials: GB
authors.lastname: Schuster
mesh_terms: D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D006735:Horseradish Peroxidase / Q000737:chemistry / Q000378:metabolism; D006861:Hydrogen Peroxide / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D049329:Nanostructures / Q000737:chemistry*; D010084:Oxidation-Reduction; D011758:Pyrroles / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D013056:Spectrophotometry, Ultraviolet; D013696:Temperature; D013876:Thiophenes / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism
chemical_list: D011758:Pyrroles; D013876:Thiophenes; D004247:DNA; D006861:Hydrogen Peroxide; D006735:Horseradish Peroxidase