title: Pancreatic extra-gastrointestinal stromal tumour masquerading as a bleeding duodenal mass.
abstract: We describe a 55-year-old man presenting to our institution with a gastrointestinal bleed. He was found to have a 5 cm pancreatic extra-gastrointestinal stromal tumours (EGISTs) eroding into the duodenum and ampulla of Vater. Pancreaticoduodenectomy was performed and the tumour was noted to be positive for CD117 and CD34 with six mitotic figures per 50/high-powered field. At 5 months postoperatively he is receiving treatment with imatinib and doing well. To the best of our knowledge, our patient is only the 18th case reported in the literature to date.
authors.affiliation: Department of Surgery, Western Michigan University School of Medicine, Kalamazoo, Michigan, USA.
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Wegge
authors.forename: David M
authors.initials: DM
authors.lastname: Bartholomew
authors.forename: Leandra H
authors.initials: LH
authors.lastname: Burke
authors.forename: Lisa A
authors.initials: LA
authors.lastname: Miller
mesh_terms: D018952:Antigens, CD34 / Q000097:blood; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004379:Duodenal Neoplasms / Q000175:diagnosis*; D004386:Duodenum / Q000473:pathology* / Q000601:surgery; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D046152:Gastrointestinal Stromal Tumors / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D000068877:Imatinib Mesylate; D008297:Male; D008875:Middle Aged; D008938:Mitosis; D010179:Pancreas / Q000473:pathology* / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D016577:Pancreaticoduodenectomy; D010879:Piperazines / Q000627:therapeutic use; D019009:Proto-Oncogene Proteins c-kit / Q000097:blood; D011743:Pyrimidines / Q000627:therapeutic use
chemical_list: D018952:Antigens, CD34; D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate; D019009:Proto-Oncogene Proteins c-kit