title: [Ovarian cryopreservation: what future?].
abstract: Ovarian cortex cryobanking is a technique of fertility preservation that led to the birth of about 20 children in the world since 2004. Its main limitations are low follicular survival rate after thawing and transplantation and the risk of disease reintroduction. A lot of research is currently conducted in order to optimize both efficacy and safety of the graft and to develop alternative techniques to restore fertility. These advances will allow oncologists to offer this technique to a growing number of patients in the context of fertility preservation (for medical or social indications), but also in other indications such as puberty induction or menopause treatment.
authors.affiliation: Service de médecine et biologie de la reproduction, CHU Nantes, 38, boulevard Jean-Monnet, 44093 Nantes cedex 1, France. sophie.mirallie@chu-nantes.fr
authors.forename: S
authors.initials: S
authors.lastname: Mirallié
authors.forename: T
authors.initials: T
authors.lastname: Fréour
authors.forename: P
authors.initials: P
authors.lastname: Barrière
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects; D015925:Cryopreservation / Q000639:trends*; D005260:Female; D059247:Fertility Preservation / Q000379:methods* / Q000639:trends*; D006085:Graft Survival; D006801:Humans; D009369:Neoplasms / Q000628:therapy; D006080:Ovarian Follicle / Q000502:physiology; D010053:Ovary / Q000502:physiology* / Q000637:transplantation; D016649:Primary Ovarian Insufficiency / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects
chemical_list: D000970:Antineoplastic Agents