title: Quantitation of proteinuria by spot urine sampling.
abstract: Few studies have shown that calculation of protein/creatinine ratio in a spot urine sample correlates well with the 24-hour urine collection. A study was conducted to compare the accuracy of a spot urinary protein/creatinine ratio (P/C ratio) and urinary dipstick (albustix) with the 24-hour urine protein (24-HUP). Fifty samples from 26 patients were collected. This included a 24-hour urine sample followed by the next voided spot sample. The protein/creatinine ratio was calculated and dipstick (albustix) was performed on the spot sample. This was compared with the 24-hour urine protein excretion. The correlation between the three samples was statistically highly significant (p=<0.001) for all levels of proteinuria. The normal value of protein/creatinine ratio in Indian children was also estimated on 100 normal children attending the OPD and was calculated to be 0.053 (S.E of mean±0.003).
authors.affiliation: Dept. of Child Health-Unit II, Christian Medical College, 632004 Vellore, Tamil Nadu India.
authors.forename: Indira
authors.initials: I
authors.lastname: Agarwal
authors.forename: Chellam
authors.initials: C
authors.lastname: Kirubakaran
authors.lastname: Markandeyulu
authors.lastname: Selvakumar
keywords: Proteinuria; mean; nephrotic syndrome; spot urine sampling