title: Rapidly progrediating aortic valve infective endocarditis in an intravenous drug user treated by antibiotics and surgery.
abstract: We report the case of a 22-year old male, a self-confessed recreational drug user who developed cardiogenic shock because of severe destruction of the aortic valve by rapidly progressive aortic valve endocarditis. The disease progression was acute; in a matter of days, the clinical manifestations were life-threatening necessitating urgent aortic valve replacement surgery. Cultivation revealed Streptococcus viridans as the microbial agent. Subsequent recovery with antibiotic treatment was without complication. This case report shows that immediately performed transoesophageal echocardiography and early consultation with a cardiac surgeon has fundamental importance in diagnosis and management of acute infective endocarditis in haemodynamically instable patients.
authors.affiliation: Department of Internal Medicine--Cardioangiology, First University Hospital and Charles University in Prague, Faculty of Medicine in Hradec Králové, Czech Republic.
authors.forename: Malkia S
authors.initials: MS
authors.lastname: Swedi
authors.forename: Pudil
authors.initials: P
authors.lastname: Radek
authors.forename: Jirí
authors.initials: J
authors.lastname: Mand'dák
mesh_terms: D000208:Acute Disease; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001021:Aortic Valve / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000382:microbiology / Q000601:surgery / Q000628:therapy*; D004697:Endocarditis, Bacterial / Q000382:microbiology / Q000601:surgery / Q000628:therapy*; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D012770:Shock, Cardiogenic / Q000209:etiology; D013290:Streptococcal Infections / Q000601:surgery / Q000628:therapy*; D015819:Substance Abuse, Intravenous / Q000150:complications*; D034363:Viridans Streptococci; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents