title: [New diagnostic imaging approaches in multiple myeloma].
abstract: Multiple myeloma (MM) is a neoplastic monoclonal proliferation of plasma cells, mainly involving bone marrow. To properly stage and manage patients with MM the clinician needs at first a complete skeletal survey. Today none of diagnostic imaging methods is able to answer alone to all questions in staging, treatment and follow up. Bone scintigraphy is affected by a low sensitivity. Tc-99m MIBI has been proposed in staging and in follow-up , with most relevant clinical information deriving from the correlation of its whole body uptake's distribution with extent and activity of the disease. PET - FDG has been proposed in MM for its skill to detect whole-body metabolic active disease, producing relevant information in staging and prognosis. First studies demonstrated that PET-FDG is more sensitive than other imaging modalities for localizing extra medullary sites of disease.
authors.affiliation: Seconda Universita di Napoli, Napoli, Italy. andreavaccaro1971@libero.it
authors.forename: Andrea
authors.initials: A
authors.lastname: Vaccaro
authors.forename: Maria Rosaria
authors.initials: MR
authors.lastname: Prisco
authors.forename: Gianluca
authors.initials: G
authors.lastname: Gatta
authors.forename: Michele
authors.initials: M
authors.lastname: Scialpi
mesh_terms: D003952:Diagnostic Imaging; D006801:Humans; D009101:Multiple Myeloma / Q000175:diagnosis*; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi