title: Community outbreak of adenovirus, Taiwan, 2011.
abstract: In 2011, a large community outbreak of human adenovirus (HAdV) in Taiwan was detected by a nationwide surveillance system. The epidemic lasted from week 11 through week 41 of 2011 (March 14-October 16, 2011). Although HAdV-3 was the predominant strain detected (74%), an abrupt increase in the percentage of infections caused by HAdV-7 occurred, from 0.3% in 2008-2010 to 10% in 2011. Clinical information was collected for 202 inpatients infected with HAdV; 31 (15.2%) had severe infection that required intensive care, and 7 of those patients died. HAdV-7 accounted for 10%, 12%, and 41% of infections among outpatients, inpatients with nonsevere infection, and inpatients with severe infection, respectively (p<0.01). The HAdV-7 strain detected in this outbreak is identical to a strain recently reported in the People's Republic of China (HAdV7-HZ/SHX/CHN/2009). Absence of circulating HAdV-7 in previous years and introduction of an emerging strain are 2 factors that caused this outbreak.
authors.forename: Tsung-Pei
authors.initials: TP
authors.lastname: Tsou
authors.forename: Boon-Fatt
authors.initials: BF
authors.lastname: Tan
authors.forename: Hsin-Yu
authors.initials: HY
authors.lastname: Chang
authors.forename: Wan-Chin
authors.initials: WC
authors.lastname: Chen
authors.forename: Yuan-Pin
authors.initials: YP
authors.lastname: Huang
authors.forename: Chen-Yin
authors.initials: CY
authors.lastname: Lai
authors.forename: Yen-Nan
authors.initials: YN
authors.lastname: Chao
authors.forename: Sung-Hsi
authors.initials: SH
authors.lastname: Wei
authors.forename: Min-Nan
authors.initials: MN
authors.lastname: Hung
authors.forename: Li-Ching
authors.initials: LC
authors.lastname: Hsu
authors.forename: Chun-Yi
authors.initials: CY
authors.lastname: Lu
authors.forename: Pei-Lan
authors.initials: PL
authors.lastname: Shao
authors.forename: Jung-Jung
authors.initials: JJ
authors.lastname: Mu
authors.forename: Luan-Yin
authors.initials: LY
authors.lastname: Chang
authors.forename: Ming-Tsan
authors.initials: MT
authors.lastname: Liu
authors.forename: Li-Min
authors.initials: LM
authors.lastname: Huang
mesh_terms: D000258:Adenovirus Infections, Human / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy / Q000821:virology; D000260:Adenoviruses, Human / Q000145:classification / Q000235:genetics*; D000293:Adolescent; D036022:Capsid Proteins / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007297:Inpatients; D010045:Outpatients; D010802:Phylogeny; D011159:Population Surveillance; D011379:Prognosis; D013624:Taiwan / Q000453:epidemiology
chemical_list: D036022:Capsid Proteins; C018315:hexon capsid protein, Adenovirus