title: Plants as biofactories: glyphosate-induced production of shikimic acid and phenolic antioxidants in wounded carrot tissue.
abstract: The use of plants to produce chemical compounds with pharmaceutical and nutraceutical applications has intensified in recent years. In this regard, genetic engineering is the most commonly used tool to generate crop lines with enhanced concentrations of desirable chemicals. However, growing genetically modified plants is still limited because they are perceived as potential biological hazards that can create an ecological imbalance. The application of postharvest abiotic stresses on plants induces the accumulation of secondary metabolites and thus can be used as an alternative to genetic modification. The present project evaluated the feasibility of producing shikimic acid (SA) and phenolic compounds (PC) in wounded carrots ( Daucus carota ) treated with glyphosate. The spray application of a concentrated glyphosate solution on wounded carrot tissue increased the concentrations of SA and chlorogenic acid by ∼1735 and ∼5700%, respectively. The results presented herein demonstrate the potential of stressed carrot tissue as a biofactory of SA and PC.
authors.affiliation: Department of Biotechnology and Food Engineering, School of Biotechnology and Food, Centro de Biotecnología-FEMSA, Tecnológico de Monterrey-Campus Monterrey, E. Garza Sada 2501 Sur, CP 64849 Monterrey, NL, Mexico.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Becerra-Moreno
authors.forename: Jorge
authors.initials: J
authors.lastname: Benavides
authors.forename: Luis
authors.initials: L
authors.lastname: Cisneros-Zevallos
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Jacobo-Velázquez
mesh_terms: D000975:Antioxidants / Q000378:metabolism*; D018552:Daucus carota / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism*; D005998:Glycine / Q000031:analogs & derivatives* / Q000494:pharmacology; D006540:Herbicides / Q000494:pharmacology*; D010636:Phenols / Q000378:metabolism*; D012765:Shikimic Acid / Q000378:metabolism*; D000097797:Glyphosate
chemical_list: D000975:Antioxidants; D005998:Glycine; D006540:Herbicides; D010636:Phenols; D012765:Shikimic Acid; D000097797:Glyphosate