title: [Male gamete…spermatozoon or spermatid?].
abstract: Normal spermatogenesis results from a balance between process of cell proliferation, cell differentiation and apoptosis that concern somatic cells and germ cells. Dysfunction of spermatogenesis may be the result of constitutional or acquired abnormalities of spermatogonia stem cells or somatic cells. To overcome these problems, it seems necessary to implement preventive measures for germ stem cell preservation or substitute measures to replace them, the objective being to replicate in vivo or in vitro the process of spermatozoa production. This article will discuss the different experimental strategies for considering the in vivo or in vitro production of spermatozoa, outside the physiological process.
authors.affiliation: Laboratoire de biologie de la reproduction, CECOS, EA 4308 gamétogenèse et qualité du Gamète, IRIB, Université de Rouen, CHU hôpitaux de Rouen, CHU Charles-Nicolle, 1, rue de Germont, 76031 Rouen cedex, France. nathalie.rives@chu-rouen.fr
authors.forename: N
authors.initials: N
authors.lastname: Rives
authors.forename: J P
authors.initials: JP
authors.lastname: Milazzo
authors.forename: B
authors.initials: B
authors.lastname: Arkoun
authors.forename: A
authors.initials: A
authors.lastname: Travers
authors.forename: A
authors.initials: A
authors.lastname: Perdrix
authors.forename: A
authors.initials: A
authors.lastname: Bironneau
authors.forename: B
authors.initials: B
authors.lastname: Macé
mesh_terms: D000818:Animals; D017209:Apoptosis; D002454:Cell Differentiation; D049109:Cell Proliferation; D006801:Humans; D007248:Infertility, Male; D008297:Male; D012708:Sertoli Cells / Q000502:physiology; D013087:Spermatids / Q000502:physiology*; D013091:Spermatogenesis / Q000502:physiology*; D013094:Spermatozoa / Q000002:abnormalities / Q000502:physiology*; D013234:Stem Cells / Q000502:physiology