title: Water oxidation mechanism in photosystem II, including oxidations, proton release pathways, O-O bond formation and O2 release.
abstract: The present status of DFT studies on water oxidation in photosystem II is described. It is argued that a full understanding of all steps is close. In each S-transition, the manganese that is oxidized and the proton released are strongly implicated, and structures of all intermediates have been determined. For the S2-state, recent important experimental findings support key elements of the structure and the mechanism. In this mechanism, the O-O bond is formed between an oxyl radical in the center of the cluster and an Mn-bridging μ-oxo ligand, which was suggested already in 2006. The DFT structure of the oxygen evolving complex, suggested in 2008, is very similar to the recent high-resolution X-ray structure. Some new aspects of the interaction between P680 and the OEC are suggested. This article is part of a Special Issue entitled: Metals in Bioenergetics and Biomimetics Systems.
authors.affiliation: Department of Physics, Stockholm University, Stockholm, Sweden. ps@physto.se
authors.forename: Per E M
authors.initials: PE
authors.lastname: Siegbahn
mesh_terms: D008958:Models, Molecular; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D045332:Photosystem II Protein Complex / Q000737:chemistry*; D011522:Protons; D014867:Water / Q000737:chemistry*
chemical_list: D045332:Photosystem II Protein Complex; D011522:Protons; D014867:Water; D010100:Oxygen
keywords: Density functional theory; Energy diagrams; Oxygen evolving complex; O―O bond formation; Photosystem II; Transition states