title: Syntheses and applications of monofluorinated cyclopropanes.
abstract: The combination of a fluorine atom and a cyclopropane ring, which both possess unique structural and chemical features, can generate new relevant building blocks for the discovery of efficient fluorinated biologically active agents. In this review, we report the different strategies to access monofluorocyclopropanes and highlight some of their attractive biological applications.
authors.affiliation: INSA de Rouen and Université de Rouen, CNRS, UMR 6014 & FR 3038, COBRA, IRCOF, 1 rue Tesnière, 76821 Mont-Saint-Aignan Cedex, France.
authors.forename: Emilie
authors.initials: E
authors.lastname: David
authors.forename: Gaëlle
authors.initials: G
authors.lastname: Milanole
authors.forename: Pavel
authors.initials: P
authors.lastname: Ivashkin
authors.forename: Samuel
authors.initials: S
authors.lastname: Couve-Bonnaire
authors.forename: Philippe
authors.initials: P
authors.lastname: Jubault
authors.forename: Xavier
authors.initials: X
authors.lastname: Pannecoucke
mesh_terms: D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D006845:Hydrocarbons, Fluorinated