title: Lipid peroxidation and antioxidant vitamins in urolithasis.
abstract: The present, study was conducted to determine the level of malondialdehyde (MDA) as an index of free radial induced lipid peroxidation and antioxidant vitamins-vitamins A, vitamin C and vitamin E in 75 confirmed cases of urolithiasis. Significantly high level of MDA (p<0.001) with significantly low levels of vitamin E (p<0.001) and vitamin A (p<0.001) with no significant decrease in vitamin C (p>0.05) were observed in the plasma of urolithiasis cases as compared to normal controls. In conclusion, it appears that a role of lipid peroxidation and oxidative function exists in the pathogenesis of urolithiasis. But, the exact mechanism how this occurs remains to be elucidated.
authors.affiliation: Department of Biochemistry, Regional Institute of Medical Sciences, Pin-795004 Imphal, Manipur.
authors.forename: J
authors.initials: J
authors.lastname: Kato
authors.forename: Alice Abraham
authors.initials: AA
authors.lastname: Ruram
authors.forename: S Sekharjit
authors.initials: SS
authors.lastname: Singh
authors.forename: S Bilasini
authors.initials: SB
authors.lastname: Devi
authors.forename: Th Ibetombi
authors.initials: TI
authors.lastname: Devi
authors.forename: W Gyaneshwar
authors.initials: WG
authors.lastname: Singh
keywords: Antioxidant Vitamins; Lipid peroxidation; Malondialdehyde (MDA); Urolithiasis