title: Need for subsequent fundoplication after gastrostomy based on patient characteristics.
abstract: BACKGROUND
  Gastrostomy tube placement is common in children. Many of the conditions associated with need for gastrostomy are also associated with gastroesophageal reflux. It is not clear how many patients without complicated reflux will subsequently require a fundoplication or which conditions increase this risk. Therefore, we performed a two-center review to determine the disease-specific propensity for fundoplication after gastrostomy tube placement.
  
  
  METHODS
  The data set was retrospectively collected from two centers from 2000 to 2008. All patients underwent gastrostomy tube placement without fundoplication owing to the surgeon's discernment that fundoplication was not needed at the time. Pearson's correlation was used to evaluate the influence of patient variables and operative approach against the subsequent need for fundoplication. Significance was defined as two-tailed P ≤ 0.01. Logistic regression analysis was used to evaluate independence.
  
  
  RESULTS
  A total of 684 patients underwent gastrostomy tube placement only, of which 124 were open, 282 laparoscopic, and 278 endoscopic (percutaneous endoscopic gastrostomy). The mean patient age was 2.9 years. Subsequent fundoplication was performed in 62 patients (9.1%). The mean interval to fundoplication was 20.7 months. Cerebral palsy and anoxic brain injury had the most significant correlation with subsequent fundoplication. These were also independent predictors. The laparoscopic approach had a negative correlation with the subsequent need for fundoplication.
  
  
  CONCLUSIONS
  The low incidence of subsequent fundoplication in children who undergo gastrostomy tube placement justifies conservative use of fundoplication in the absence of complicated reflux. Those with cerebral palsy and anoxic brain injury appeared to have the greatest risk of the need for subsequent fundoplication.
authors.affiliation: Department of Surgery, Rainbow Babies and Children's Hospital, Cleveland, Ohio, USA.
authors.forename: Todd A
authors.initials: TA
authors.lastname: Ponsky
authors.forename: Alessandra C
authors.initials: AC
authors.lastname: Gasior
authors.forename: Jennifer
authors.initials: J
authors.lastname: Parry
authors.forename: Susan W
authors.initials: SW
authors.lastname: Sharp
authors.forename: Scott
authors.initials: S
authors.lastname: Boulanger
authors.forename: Robert
authors.initials: R
authors.lastname: Parry
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Ostlie
authors.forename: Shawn D
authors.initials: SD
authors.lastname: St Peter
mesh_terms: D002547:Cerebral Palsy / Q000150:complications; D002675:Child, Preschool; D004724:Endoscopy; D005260:Female; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000628:therapy*; D005774:Gastrostomy; D006801:Humans; D002534:Hypoxia, Brain / Q000150:complications; D010535:Laparoscopy; D008297:Male; D009422:Nervous System Diseases / Q000150:complications*; D012044:Regression Analysis; D012189:Retrospective Studies; D012307:Risk Factors