title: Nerve glue for upper extremity reconstruction.
abstract: Nerve glue is an attractive alternative to sutures to improve the results of nerve repair. Improved axon alignment, reduced scar and inflammation, greater and faster reinnervation, and better functional results have been reported with the use of nerve glue. The different types of nerve glue and the evidence to support or oppose their use are reviewed. Although the ideal nerve glue has yet to be developed, fibrin sealants can be used as nerve glue in select clinical situations. Technology to allow suture-free nerve repair is one development that can potentially improve functional nerve recovery and the outcomes of upper extremity reconstruction.
authors.affiliation: Division of Plastic Surgery, Department of Surgery, University of Washington, WA 98105, USA. raymond.tse@seattlechildrens.org
authors.forename: Raymond
authors.initials: R
authors.lastname: Tse
authors.forename: Jason H
authors.initials: JH
authors.lastname: Ko
mesh_terms: D000818:Animals; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006801:Humans; D016067:Nerve Transfer; D019635:Neurosurgical Procedures / Q000379:methods; D010525:Peripheral Nerves / Q000637:transplantation*; D019651:Plastic Surgery Procedures / Q000379:methods*; D020127:Recovery of Function; D013537:Sutures; D013718:Tensile Strength; D014014:Tissue Adhesives / Q000627:therapeutic use*; D034941:Upper Extremity / Q000293:injuries* / Q000601:surgery*
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives