title: Complex evolution and epidemiology of Dobrava-Belgrade hantavirus: definition of genotypes and their characteristics.
abstract: Dobrava-Belgrade virus (DOBV) is a human pathogen that has evolved in, and is hosted by, mice of several species of the genus Apodemus. We propose a subdivision of the species Dobrava-Belgrade virus into four related genotypes - Dobrava, Kurkino, Saaremaa, and Sochi - that show characteristic differences in their phylogeny, specific host reservoirs, geographical distribution, and pathogenicity for humans.
authors.affiliation: Institute of Virology, Helmut-Ruska-Haus, Charité Medical School, Berlin, Germany. boris.klempa@savba.sk
authors.forename: Boris
authors.initials: B
authors.lastname: Klempa
authors.forename: Tatjana
authors.initials: T
authors.lastname: Avsic-Zupanc
authors.forename: Jan
authors.initials: J
authors.lastname: Clement
authors.forename: Tamara K
authors.initials: TK
authors.lastname: Dzagurova
authors.forename: Heikki
authors.initials: H
authors.lastname: Henttonen
authors.forename: Paul
authors.initials: P
authors.lastname: Heyman
authors.forename: Ferenc
authors.initials: F
authors.lastname: Jakab
authors.forename: Detlev H
authors.initials: DH
authors.lastname: Kruger
authors.forename: Piet
authors.initials: P
authors.lastname: Maes
authors.forename: Anna
authors.initials: A
authors.lastname: Papa
authors.forename: Evgeniy A
authors.initials: EA
authors.lastname: Tkachenko
authors.forename: Rainer G
authors.initials: RG
authors.lastname: Ulrich
authors.forename: Olli
authors.initials: O
authors.lastname: Vapalahti
authors.forename: Antti
authors.initials: A
authors.lastname: Vaheri
mesh_terms: D000818:Animals; D005075:Biological Evolution; D005060:Europe; D005838:Genotype; D006476:Orthohantavirus / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity*; D018778:Hantavirus Infections / Q000453:epidemiology / Q000662:veterinary / Q000821:virology*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000453:epidemiology* / Q000662:veterinary / Q000821:virology; D006801:Humans; D017720:Molecular Epidemiology; D051189:Murinae; D010802:Phylogeny; D012376:Rodent Diseases / Q000453:epidemiology / Q000821:virology; D013045:Species Specificity