title: The AIDS pandemic in historic perspective.
abstract: Potent antiretroviral drugs (ART) have changed the nature of AIDS, a once deadly disease, into a manageable illness and offer the promise of reducing the spread of HIV. But the pandemic continues to expand and cause significant morbidity and devastation to families and nations as ART cannot be distributed worldwide to all who need the drugs to treat their infections, prevent HIV transmission, or serve as prophylaxis. Furthermore, conventional behavioral prevention efforts based on theories that individuals can be taught to modify risky behaviors if they have the knowledge to do so have been ineffective. Noting behavioral strategies targeting individuals fail to address broader social and political structures that create environments vulnerable to HIV spread, social scientists and public health officials insist that HIV policies must be comprehensive and also target a variety of structures at the population and environmental level. Nineteenth-century public health programs that targeted environmental susceptibility are the historical analogues to today's comprehensive biomedical and structural strategies to handle AIDS. Current AIDS policies underscore that those fighting HIV using scientific advances in virology and molecular biology cannot isolate HIV from its broader environment and social context any more than their nineteenth-century predecessors who were driven by the filth theory of disease.
authors.affiliation: University of Michigan, 1500 E. Medical Center Drive, 3119 Taubman Center, Ann Arbor, Michigan 48109-5378.
authors.forename: Powel
authors.initials: P
authors.lastname: Kazanjian
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy / Q000453:epidemiology / Q000266:history*; D044966:Anti-Retroviral Agents / Q000266:history* / Q000627:therapeutic use; D018562:Disease Transmission, Infectious / Q000517:prevention & control; D005260:Female; D015658:HIV Infections / Q000517:prevention & control / Q000635:transmission; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008297:Male; D058873:Pandemics / Q000266:history*; D011634:Public Health / Q000266:history*; D012959:Socioeconomic Factors
chemical_list: D044966:Anti-Retroviral Agents
keywords: AIDS; antiretroviral; history; prevention; structural programs; vaccine