title: Serum lipids, lipoproteins and sex-hormone binding globulin in breast cancer.
abstract: Serum levels of various lipid parameters, i.e., triglycerides, total cholesterol, alpha lipoprotein or high density lipoprotein (HDL)-cholesterol and beta lipoprotein or low density lipoprotein (LDL)-cholesterol were measured in a total of 138 histologically proven cases of breast cancer along with 146 control women. The mean levels of serum triglycerides, total cholesterol and LDL-cholesterol were found to be significantly higher in breast cancer cases as compared to controls. However, lower mean levels of serum HDL-cholesterol and sex-hormone binding glubulin (SHBG) were observed in breast cancer patients than the control subjects. The results indicate a probable relation between serum lipids and the activity of sex-hormones. Moreover, the study reflects an overall disturbance of lipid metabolism in the pathological process of breast cancer.
authors.affiliation: Institute of Cytology and Preventive Oncology (ICMR), Maulana Azad Medical College, 110002 New Delhi.
authors.forename: A
authors.initials: A
authors.lastname: Ray
authors.forename: S L
authors.initials: SL
authors.lastname: Dayalu Naik
authors.forename: A K
authors.initials: AK
authors.lastname: Bahadur
authors.forename: S T
authors.initials: ST
authors.lastname: Pasha
authors.forename: R S
authors.initials: RS
authors.lastname: Rautela
authors.forename: B K
authors.initials: BK
authors.lastname: Sharma
keywords: Serum lipids; related proteins and female breast cancer