title: [Modification of pertussis vaccination schedule in Chile, immunization of special groups and control strategies: Commentary from the Consultive Committee of Immunizations of The Chilean Society of Infectious Diseases].
abstract: In Chile, an increased number of notifications of cases of whooping cough was detected at the beginning of October 2010, and maintained through 2012. Accumulated cases during 2011 were 2,581 (15.0 per 100,000), which is greater than the number of cases registered during the period 2008-2010 (2,460 cases). On the other hand, the local sanitary authority introduced a modification of pertussis vaccination schedule (starting 2012), which consists in the replacement of the second booster of pertussis vaccine (DTwP, administered to 4-year-old children) as well as diphtheria-tetanus toxoid (dT, administered to second grade scholars) for an acellular pertussis vaccine with reduced antigenic content (dTpa), which will be administrated to first grade scholars. The Consultive Committee of Immunizations considers that the modification is adequate, since it extends the age of protection, reducing at least in theory the infection in older scholars and adolescents -who are significant sources of transmission of Bordetella pertussis to infants- using an adequate vaccine formulation (acellular pertussis vaccine). The available evidence regarding vaccination in special groups (adolescents and adults, health-care workers and pregnant women) and cocooning strategy are commented.
authors.affiliation: División de Pediatría, Facultad de Medicina, Pontificia Universidad Católica de Chile, Chile.
authors.forename: Marcela
authors.initials: M
authors.lastname: Potin
authors.forename: Jaime
authors.initials: J
authors.lastname: Cerda
authors.forename: Lily
authors.initials: L
authors.lastname: Contreras
authors.forename: Alma
authors.initials: A
authors.lastname: Muñoz
authors.forename: Erna
authors.initials: E
authors.lastname: Ripoll
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Vergara
mesh_terms: D000293:Adolescent; D000328:Adult; D002675:Child, Preschool; D002677:Chile / Q000453:epidemiology; D003245:Consensus Statements as Topic; D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines / Q000592:standards*; D005260:Female; D006801:Humans; D007115:Immunization Schedule; D007223:Infant; D008297:Male; D032541:Mass Vaccination / Q000379:methods*; D017063:Outcome Assessment, Health Care; D011247:Pregnancy; D014917:Whooping Cough / Q000453:epidemiology / Q000517:prevention & control*; D055815:Young Adult
chemical_list: D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines