title: Decision making is affected in obstructive sleep apnoea syndrome.
abstract: We assessed decision making in 20 patients newly diagnosed with obstructive sleep apnoea (OSA) and 20 healthy controls with the Iowa Gambling Task (IGT), which evaluates the ability to learn to sacrifice immediate rewards in favour of long-term gains. A standard neuropsychological battery was administered. Switching scores tended to be lower in patients. Patients persisted in selecting risky decks throughout the IGT, whereas controls behaved normally. Performance was correlated with hypoxaemia. Brain regions underlying decision making may be affected by OSA-related hypoxaemia.
authors.affiliation: UMR 5263 CNRS - EPHE-Toulouse II University, CLLE-LTC, Laboratory, France. daurat@univ-tlse2.fr
authors.forename: Agnès
authors.initials: A
authors.lastname: Daurat
authors.forename: Matthieu
authors.initials: M
authors.lastname: Ricarrère
authors.forename: Michel
authors.initials: M
authors.lastname: Tiberge
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003072:Cognition Disorders / Q000209:etiology*; D003657:Decision Making / Q000502:physiology*; D005260:Female; D005717:Games, Experimental; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000523:psychology; D013223:Statistics as Topic