title: Two new compounds from an endophytic fungus Alternaria solani.
abstract: Two new secondary metabolites, named 7-dehydroxyl-zinniol (1) and 20-hydroxyl-ergosta-4,6,8(14),22-tetraen-3-one (2), were isolated from the culture of Alternaria solani, an endophytic fungal strain residing in the roots of Aconitum transsectum. Their structures were elucidated on the basis of comprehensive spectroscopic analyses including IR, ESI-MS, HR-ESI-MS, 1D and 2D NMR. Biological activity tests indicated that compound 1 showed moderate anti-HBV activity.
authors.affiliation: School of Agriculture and Biological Technic, Yunnan Agricultural University, Kunming 650201, China.
authors.forename: Hong-Lian
authors.initials: HL
authors.lastname: Ai
authors.forename: Li-Mei
authors.initials: LM
authors.lastname: Zhang
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Chen
authors.forename: Shu-Hui
authors.initials: SH
authors.lastname: Zi
authors.forename: Hong
authors.initials: H
authors.lastname: Xiang
authors.forename: Da-Ke
authors.initials: DK
authors.lastname: Zhao
authors.forename: Yong
authors.initials: Y
authors.lastname: Shen
mesh_terms: D031841:Aconitum / Q000382:microbiology; D000528:Alternaria / Q000737:chemistry*; D002783:Cholestenones / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000382:microbiology; D014992:Xylenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: C578213:20-hydroxyl-ergosta-4,6,8(14),22-tetraen-3-one; C578212:7-dehydroxyl-zinniol; D002783:Cholestenones; D014992:Xylenes; C015860:ergosta-4,6,8(14),22-tetraen-3-one