title: [Revival of selected well-tried antibiotics. Special features of the antiinfective agents penicillin G, fosfomycin, aztreonam and colistin].
abstract: Although a worldwide increasing incidence of bacterial infections with panresistant pathogens may need innovative antiinfective agents, no breakthrough developments can be expected in the near future. As a consequence, well-tried antibiotics like aztreonam, fosfomycin and colistin, are experiencing a clinical revival, particularly if they are used in an improved manner. Even penicillin G with its narrow spectrum of antimicrobial activity remains an important considerable agent of first choice in special indications compared to broad spectrum antiinfectives.
authors.affiliation: Universitätsapotheke, Rõntgenweg 9, 72076 Tübingen. Hans-Peter.Lipp@med.uni-tuebingen.de
authors.forename: Hans-Peter
authors.initials: HP
authors.lastname: Lipp
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001398:Aztreonam / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D003091:Colistin / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D005578:Fosfomycin / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced; D010400:Penicillin G / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D005578:Fosfomycin; D001398:Aztreonam; D010400:Penicillin G; D003091:Colistin