title: [Dw-MRI and bone scintigraphy in monitoring radio-therapy response in bone metastases].
abstract: Bone is one of the most common sites of metastatic spread of malignancy, with possible deleterious effects including pain, hypercalcemia, and pathologic fracture. External beam radiotherapy (EBRT) remains the mainstay for treatment of painful bone metastases. Diffusion-weighted MRI (DW-MRI) has been described as an efficient method to differentiate good and poor responders to radiotherapy in bone metastases patients. The addition of DWI to conventional whole-body MRI sequences enhanced lesion conspicuity and improved diagnostic accuracy. We evaluate bone metastases patients with bone scintigraphy and DW-MRI.  With technical optimization, whole-body MRI with DWI, as a nonionizing imaging modality, may potentially be useful as an alternative method to bone scintigraphy in the management of bone metastases.
authors.affiliation: Seconda Universita di Napoli, Napoli, Italy. antonioraucci@gmail.com
authors.forename: Antonio
authors.initials: A
authors.lastname: Raucci
authors.forename: Gianluca
authors.initials: G
authors.lastname: Gatta
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Cuccurullo
mesh_terms: D001859:Bone Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000556:secondary*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging