title: Recombinant factor VIIa: use in fatal post partum hemorrhage - Indian experience case series and review of literature.
abstract: Postpartum hemorrhage is leading cause of maternal mortality and still remains a challenging condition to treat and hysterectomy may be required to control the bleeding once medical interventions fail. These strategies are not always successful and a direct approach in activating the coagulation system can be more effective and life saving. We describe here the mechanism of action of rFVIIa, review of literature and its use in 10 cases with different causes for PPH with good response.
authors.affiliation: CARE Hospitals, Banjara Hills, Hyderabad, 500 082 AP India.
authors.forename: Shailesh R
authors.initials: SR
authors.lastname: Singi
authors.forename: Evita
authors.initials: E
authors.lastname: Fernandez
authors.forename: Sunil T
authors.initials: ST
authors.lastname: Pandya
authors.forename: H R
authors.initials: HR
authors.lastname: Badrinath
keywords: Bleeding; Coagulation; Hemorrhage; NICE registry; NovoSeven; PPH; rFVIIa