title: Role of practice-based research networks in comparative effectiveness research.
abstract: Comparative effectiveness research fundamentally reorients how clinical evidence is generated and used with the goal of providing actionable information to decision-makers. To achieve this, it is vital that decision-makers and the research enterprise are engaged from research inception, to evidence generation and translation. Practice-based research networks are affiliated clinicians in diverse communities with the goal of conducting research to improve care. Practice-based research networks have the potential to advance all phases of the comparative effectiveness research cycle. The aim of this paper is to explore current and potential roles of practice-based research networks in conducting comparative effectiveness research.
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Hartung
authors.forename: Jeanne-Marie
authors.initials: JM
authors.lastname: Guise
authors.forename: Lyle J
authors.initials: LJ
authors.lastname: Fagnan
authors.forename: Melinda M
authors.initials: MM
authors.lastname: Davis
authors.forename: Kurt C
authors.initials: KC
authors.lastname: Stange
mesh_terms: D057186:Comparative Effectiveness Research; D003657:Decision Making; D019317:Evidence-Based Medicine / Q000379:methods*; D006801:Humans; D018802:Patient-Centered Care / Q000458:organization & administration*; D057170:Translational Research, Biomedical; D014481:United States