title: A new triterpene saponin from the roots of Ilex pubescens.
abstract: A new triterpene saponin, ilexoside P (1), along with three known triterpene saponins, ilexoside O (2), ilexsaponin B3 (3) and ilexpublesnin A (4) was isolated from the roots of Ilex pubescens. Their chemical structures were elucidated on the basis of UV, IR, MS, and NMR spectroscopic analyses coupled with chemical degradation. In addition, the xanthine oxidase (XOD) inhibitory activity of the isolated saponins was reported. Compound 1 exhibited weak XOD inhibitory activity in the test.
authors.affiliation: Chemistry Science and Technology School, Zhanjiang Normal University, 29 Cunjin Road, Zhanjiang 524048, P.R. China. zlzhou@hotmail.com
authors.forename: Zhong-Liu
authors.initials: ZL
authors.lastname: Zhou
authors.forename: Zong-Cai
authors.initials: ZC
authors.lastname: Feng
authors.forename: Chun-Yan
authors.initials: CY
authors.lastname: Fu
authors.forename: Li
authors.initials: L
authors.lastname: Zeng
mesh_terms: D004789:Enzyme Activation / Q000187:drug effects; D030017:Ilex / Q000737:chemistry*; D018517:Plant Roots / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry* / Q000494:pharmacology; D014315:Triterpenes / Q000737:chemistry* / Q000494:pharmacology; D014969:Xanthine Oxidase / Q000378:metabolism
chemical_list: D012503:Saponins; D014315:Triterpenes; D014969:Xanthine Oxidase