title: PET/CT of cancer patients: part 2, deformable registration imaging before and after chemotherapy for radiation treatment planning in head and neck cancer.
abstract: OBJECTIVE
  The purpose of this perspective is to discuss the use of deformable registration as a tool for image fusion to integrate information from PET/CT scans obtained before and after chemotherapy to assist definition of radiation targets in the management of head and neck cancer.
  
  
  CONCLUSIONS
  The consistent method for target delineation described capitalizes on the capability of deformable registration to compensate for changes in position and accurately represent evolving spatial relationships between normal anatomy and areas at risk of disease.
authors.affiliation: Harvard Radiation Oncology Program, Boston, MA, USA.
authors.forename: Jonathan D
authors.initials: JD
authors.lastname: Schoenfeld
authors.forename: Nataliya
authors.initials: N
authors.lastname: Kovalchuk
authors.forename: Rathan M
authors.initials: RM
authors.lastname: Subramaniam
authors.forename: Minh Tam
authors.initials: MT
authors.lastname: Truong
mesh_terms: D000465:Algorithms; D005260:Female; D019788:Fluorodeoxyglucose F18; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000532:radiotherapy; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging / Q000379:methods*; D049268:Positron-Emission Tomography; D017410:Practice Guidelines as Topic; D019275:Radiopharmaceuticals; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D050397:Radiotherapy, Intensity-Modulated; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18