title: Ivermectin residues in squab.
abstract: No drugs have been approved for the treatment of parasitic nematodes in pigeons, but ivermectin, a broad-spectrum endectocide, has been used extra-label by prescription. Producers currently allow for a 2-wk withdrawal time before marketing squabs. However, because its use is extra-label there is no legal maximum residue limit for ivermectin in squab meat. The purpose of this study was to examine the depletion of ivermectin (passed by the parents to the squabs) from the tissues of squab. Adult pigeons brooding squab were treated with ivermectin in their drinking water (3.3 µg/mL) for 3 d. After dosing the parents, the ivermectin concentration of the breast meat and liver of squabs was found to be greater than the maximum residual limits established for livestock, indicating that ivermectin was transferred from the parents to the squabs. However, ivermectin was not detected in either the breast meat or the livers of squabs 1 wk after dosing. These results indicate that there is a rapid decline in tissue levels of ivermectin in squab.
authors.affiliation: University of British Columbia, Vancouver, British Columbia, V6T 1Z4 Canada. darin.bennett@ubc.ca
authors.forename: D C
authors.initials: DC
authors.lastname: Bennett
authors.forename: K M
authors.initials: KM
authors.lastname: Cheng
mesh_terms: D000818:Animals; D000977:Antiparasitic Agents / Q000737:chemistry* / Q000378:metabolism; D010856:Columbidae; D060766:Drinking Water; D004350:Drug Residues / Q000737:chemistry*; D005506:Food Contamination; D007559:Ivermectin / Q000737:chemistry* / Q000378:metabolism; D008099:Liver / Q000737:chemistry; D008460:Meat / Q000032:analysis*
chemical_list: D000977:Antiparasitic Agents; D060766:Drinking Water; D007559:Ivermectin