title: Ag(I)-catalyzed aminofluorination of alkynes: efficient synthesis of 4-fluoroisoquinolines and 4-fluoropyrrolo[α]isoquinolines.
abstract: A silver-catalyzed intramolecular oxidative aminofluorination of alkynes has been developed by using NFSI as a fluorinating reagent. This reaction represents an efficient method for the synthesis of various 4-fluoroisoquinolines and 4-fluoropyrrolo[α]isoquinolines.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Lingling Road, Shanghai, 200032, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Xu
authors.forename: Guosheng
authors.initials: G
authors.lastname: Liu
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012835:Silver Nitrate / Q000737:chemistry*
chemical_list: D000480:Alkynes; D007546:Isoquinolines; D012835:Silver Nitrate