title: Measles outbreak in Andalusia, Spain, January to August 2011.
abstract: On 7 January 2011, a six year-old child living in a Roma community near Seville, southern Spain, was hospitalised with measles. Contact tracing identified a probable index case with onset of symptoms on 20 December 2011 and several unreported cases among children under the age of 15 years in the same town. The outbreak initially spread in districts in the city of Seville with a high proportion of Roma residents, and later to other cities and towns in Andalusia. While some towns experienced wide spread of the disease with significant clusters of cases, most of the affected locations saw non-clustered cases or very few secondary cases. The outbreak resulted in 1,759 confirmed or probable cases of which 393 (19%) required hospitalisation. Measles virus of genotype D4 was diagnosed in more than half of the cases. Significant differences (p<0.0001) by age group were found between clustered and non-clustered cases. The highest proportion of clustered cases occurred in the age group of 5-14 yearolds, while the highest proportion of non-clustered cases was seen in those older than 29 years. The last confirmed case related to this outbreak was reported on 20 August 2011.
authors.affiliation: Regional Ministry of Health of the Government of Andalusia, Seville, Spain. josem.mayoral.sspa@juntadeandalucia.es
authors.forename: Jm
authors.initials: J
authors.lastname: Mayoral Cortes
authors.forename: E
authors.initials: E
authors.lastname: Perez Morilla
authors.forename: V
authors.initials: V
authors.lastname: Gallardo Garcia
authors.forename: Jm
authors.initials: J
authors.lastname: Navarro Mari
authors.forename: M
authors.initials: M
authors.lastname: Perez Ruiz
authors.forename: R
authors.initials: R
authors.lastname: Hermosilla
authors.forename: J
authors.initials: J
authors.lastname: Diaz-Borrego
authors.forename: E
authors.initials: E
authors.lastname: Rodriguez Romero
authors.forename: J
authors.initials: J
authors.lastname: Ruiz Fernandez
mesh_terms: D000293:Adolescent; D000328:Adult; D000554:Ambulatory Care Facilities / Q000592:standards; D002648:Child; D002675:Child, Preschool; D016358:Contact Tracing / Q000706:statistics & numerical data / Q000639:trends; D018563:Disease Notification; D004196:Disease Outbreaks / Q000517:prevention & control / Q000706:statistics & numerical data; D004334:Drug Administration Schedule; D005260:Female; D006282:Health Personnel / Q000592:standards; D006760:Hospitalization / Q000706:statistics & numerical data / Q000639:trends; D006801:Humans; D017589:Immunization Programs / Q000458:organization & administration / Q000592:standards; D007223:Infant; D007231:Infant, Newborn; D008457:Measles / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D008458:Measles Vaccine / Q000008:administration & dosage*; D008459:Measles virus / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity; D008507:Medically Underserved Area; D060888:Real-Time Polymerase Chain Reaction; D018571:Sentinel Surveillance; D017422:Sequence Analysis, DNA; D013030:Spain / Q000453:epidemiology; D000078329:Workforce
chemical_list: D008458:Measles Vaccine