title: Cooperative formation of silver(I)-mediated base pairs.
abstract: DNA double helices comprising two neighbouring artificial imidazole-Ag(I)-imidazole base pairs incorporate the Ag(I) ions in a cooperative fashion. Isothermal titration calorimetry data confirm the theoretically predicted binding stoichiometry and indicate that Ag(I) binds with association constants >10(6) M(-1) to the metal-free DNA duplex.
authors.affiliation: Westfälische Wilhelms-Universität Münster, Institut für Anorganische und Analytische Chemie, Corrensstr. 28/30, 48149 Münster, Germany.
authors.forename: Kristina
authors.initials: K
authors.lastname: Petrovec
authors.forename: Bart Jan
authors.initials: BJ
authors.lastname: Ravoo
authors.forename: Jens
authors.initials: J
authors.lastname: Müller
mesh_terms: D020029:Base Pairing; D002151:Calorimetry; D004247:DNA / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D012834:Silver; D004247:DNA