title: Controlling radicals in the powerhouse: development of MitoSOD.
abstract: Investigators in the redox biology field have long recognized the unique role mitochondrial superoxide generation plays in physiological signaling and in dysregulated bioenergetic dysfunction. Pharmacological manipulation has been challenging, and in this issue of Chemistry & Biology, Kelso and colleagues present the synthesis and characterization of a novel mitochondrial-targeted SOD mimetic, MitoSOD.
authors.forename: Tanecia
authors.initials: T
authors.lastname: Mitchell
authors.forename: Balu K
authors.initials: BK
authors.lastname: Chacko
authors.forename: Victor
authors.initials: V
authors.lastname: Darley-Usmar