title: A severely infected diabetic foot treated successfully without using systemic antibiotics.
abstract: About 50% to 70% of all lower extremity amputations are related to diabetes infection. And antibiotic therapy is routinely used for all infected wounds to reduce the mortality of diabetic foot. Here, we report a case of diabetic foot with acute and deep severe infection. During hospital therapy, we used negative pressure therapy and extensive debridement without systemic antibiotic application, and we successfully rescued a foot from amputation. Negative pressure therapy and extensive debridement are very important and effective methods to control infection and promote wound healing in diabetes foot.
authors.affiliation: Jiaotong University, Shanghai, People's Republic of China.
authors.forename: Ming
authors.initials: M
authors.lastname: Tian
authors.forename: Yu-Zhi
authors.initials: YZ
authors.lastname: Jiang
authors.forename: Yi-Wen
authors.initials: YW
authors.lastname: Niu
authors.forename: Yu-Rui
authors.initials: YR
authors.lastname: Xiao
authors.forename: Shu-Liang
authors.initials: SL
authors.lastname: Lu
authors.forename: Xi-Qiao
authors.initials: XQ
authors.lastname: Wang
mesh_terms: D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003646:Debridement / Q000379:methods*; D017719:Diabetic Foot / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D023821:Limb Salvage / Q000379:methods; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology*; D014946:Wound Infection / Q000175:diagnosis / Q000601:surgery*
chemical_list: D000900:Anti-Bacterial Agents