title: Can summary nitrite+nitrate content serve as an indicator of NO synthesis intensity in body tissues?
abstract: Studies with the use of a highly specific enzymatic sensor demonstrated that, contrary to the common opinion, normally nitrate is in fact not present in the most important physiological fluids. NO metabolites in the amniotic fluid and semen are mainly presented by NO donor compounds. Therefore, the intensity of NO synthesis can be evaluated by the total content of all its metabolites, but not by the widely used summary nitrite+nitrate content.
authors.affiliation: N. I. Pirogov Russian National Research Medical University, Moscow, Russia. vtitov43@yandex.ru
authors.forename: V Yu
authors.initials: VY
authors.lastname: Titov
authors.forename: A V
authors.initials: AV
authors.lastname: Ivanova
authors.forename: V A
authors.initials: VA
authors.lastname: Petrov
authors.forename: V A
authors.initials: VA
authors.lastname: Serezhenkov
authors.forename: V D
authors.initials: VD
authors.lastname: Mikoyan
authors.forename: A F
authors.initials: AF
authors.lastname: Vanin
authors.forename: A N
authors.initials: AN
authors.lastname: Osipov
mesh_terms: D000653:Amniotic Fluid / Q000737:chemistry*; D000818:Animals; D001064:Appendicitis / Q000097:blood; D002417:Cattle; D002642:Chick Embryo; D002764:Cholecystitis / Q000097:blood; D006801:Humans; D015523:Maxillary Sinusitis / Q000097:blood; D009566:Nitrates / Q000032:analysis; D009569:Nitric Oxide / Q000032:analysis* / Q000378:metabolism; D020030:Nitric Oxide Donors / Q000032:analysis / Q000378:metabolism; D009573:Nitrites / Q000032:analysis; D009603:Nitroso Compounds / Q000032:analysis; D009928:Organ Specificity; D026403:S-Nitrosothiols / Q000032:analysis; D012661:Semen / Q000737:chemistry*; D013045:Species Specificity
chemical_list: D009566:Nitrates; D020030:Nitric Oxide Donors; D009573:Nitrites; D009603:Nitroso Compounds; D026403:S-Nitrosothiols; D009569:Nitric Oxide