title: Prognosis of patients with gastric cancer who underwent proximal gastrectomy.
abstract: Proximal gastrectomy (PG) has been introduced for patients who are preoperatively diagnosed with early gastric cancer located in the upper third of the stomach. In the present study, we compared the prognosis of patients who underwent PG with that of patients who underwent total gastrectomy (TG). Between 1997 and 2006, 51 patients were diagnosed with early gastric cancer located in the upper third of the stomach and underwent PG. In the same period, 35 patients were diagnosed with early gastric cancer and underwent TG. Of these, in 24 patients, the cancer was localized in the middle to upper part of the stomach, and 11 patients had multiple cancers. We compared the clinicopathologic differences and prognoses between the two groups. Significantly fewer lymph nodes were dissected in the PG group (mean, 18.2) than in the TG group (mean, 36.6;P < 0.001). Complications were detected in 17.6% of patients in the PG group and in 14.3% of patients in the TG group, which was not significant (P = 0.678). The overall and disease-specific 5-year survival rates in the 51 patients who underwent PG (88.7% and 97.1%, respectively) were not different from those in the 35 patients who underwent TG (87.6% and 93.4%; P = 0.971 and P = 0.553; respectively). These findings indicate that PG can be performed safely and may have various advantages compared with TG in terms of patients' daily lives.
authors.affiliation: Department of Surgery, Division of Surgical Oncology, Faculty of Medicine, Tottori University, Yonago, Japan. masaike@med.tottori-u.ac.jp
authors.forename: Masahide
authors.initials: M
authors.lastname: Ikeguchi
authors.forename: Abdul
authors.initials: A
authors.lastname: Kader
authors.forename: Seigo
authors.initials: S
authors.lastname: Takaya
authors.forename: Youji
authors.initials: Y
authors.lastname: Fukumoto
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Osaki
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Saito
authors.forename: Shigeru
authors.initials: S
authors.lastname: Tatebe
authors.forename: Toshiro
authors.initials: T
authors.lastname: Wakatsuki
mesh_terms: D018572:Disease-Free Survival; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D011379:Prognosis; D013274:Stomach Neoplasms / Q000401:mortality* / Q000601:surgery*