title: Mathematical modelling of the lower urinary tract.
abstract: The lower urinary tract is one of the most complex biological systems of the human body as it involved hydrodynamic properties of urine and muscle. Moreover, its complexity is increased to be managed by voluntary and involuntary neural systems. In this paper, a mathematical model of the lower urinary tract it is proposed as a preliminary study to better understand its functioning. Furthermore, another goal of that mathematical model proposal is to provide a basis for developing artificial control systems. Lower urinary tract is comprised of two interacting systems: the mechanical system and the neural regulator. The latter has the function of controlling the mechanical system to perform the voiding process. The results of the tests reproduce experimental data with high degree of accuracy. Also, these results indicate that simulations not only with healthy patients but also of patients with dysfunctions with neurological etiology present urodynamic curves very similar to those obtained in clinical studies.
authors.affiliation: Computing Technology and Data Processing, University of Alicante, Carretera San Vicente del Raspeig s/n, San Vicente del Raspeig, 03690 Alicante, Spain.
authors.forename: Antonio Soriano
authors.initials: AS
authors.lastname: Paya
authors.forename: Daniel Ruiz
authors.initials: DR
authors.lastname: Fernandez
authors.forename: David
authors.initials: D
authors.lastname: Gil
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Garcia Chamizo
authors.forename: Francisco Macia
authors.initials: FM
authors.lastname: Perez
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D006801:Humans; D008954:Models, Biological; D008959:Models, Neurological; D009130:Muscle, Smooth / Q000473:pathology; D012984:Software; D013997:Time Factors; D001743:Urinary Bladder / Q000294:innervation / Q000502:physiology*; D014551:Urinary Tract / Q000294:innervation; D014554:Urination / Q000502:physiology; D014563:Urodynamics / Q000502:physiology*