title: Rare case of iatrogenic pan hypopituitarism.
abstract: Excess glucocorticoids exert feedback suppression on hypothalamus and pituitary, Thereby the release of CRH and ACTH are suppressed which results in bilateral adrenal cortical atrophy, at the same time patients is having features of latrogenic Cushing syndrome.The interesting part of this case is excess glucocorticoids have exerted cross feedback suppression on hypothalamus and pituitary resulting in suppression of release of GHRH, GH and LHRH, LH and FSH also from hypothalamus and pituitary thereby resulting in growth retardation as well as hypogonadotrophic hypogonadism. Combination of feedback and cross feedback effect of excess glucocorticoids are seen in one patient which is an interesting part of the case.
authors.affiliation: Department of General Medicine, Yeneopya Medical College and Hospital, Kodialbail, 575003 Mangalore, Karnataka State.
authors.forename: Saraswathi
authors.initials: S
authors.lastname: Susarla
authors.forename: Mohammed
authors.initials: M
authors.lastname: Kunhi
authors.forename: Kishore
authors.initials: K
authors.lastname: Kumar
authors.forename: Praveen
authors.initials: P
authors.lastname: Shetty