title: Plexiform angiomyxoid myofibroblastic tumor of the stomach: report of two cases and review of the literature.
abstract: Plexiform angiomyxoid myofibroblastic tumor (PAMT) of the stomach is a recently recognized entity. Because of its rarity, only 22 cases have been reported in the English-language literature and most of these are single case reports. We report two cases of gastric PAMT. The tumor cells were bland and plexiform arranged in a myxoid stroma, which was positive for alcian blue. Immunohistochemically, the tumor cells were positive for smooth muscle actin, but negative for c-kit, CD34, desmin, S-100 protein, epithelial membrane antigen, neurofilament, and protein kinase C-theta. Mutation analyses for exon 9, 11, 13, and 17 of KIT genes and 12, 14, and 18 of the platelet-derived growth factor receptor alpha (PDGFRA) genes were performed and the tumors were wild-type for mutation.
authors.affiliation: Department of Pathology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
authors.forename: Youngran
authors.initials: Y
authors.lastname: Kang
authors.forename: Wonkyung
authors.initials: W
authors.lastname: Jung
authors.forename: In-Gu
authors.initials: IG
authors.lastname: Do
authors.forename: Eui Jin
authors.initials: EJ
authors.lastname: Lee
authors.forename: Min Hyeong
authors.initials: MH
authors.lastname: Lee
authors.forename: Kyoung-Mee
authors.initials: KM
authors.lastname: Kim
authors.forename: Jongsang
authors.initials: J
authors.lastname: Choi
keywords: Angiomyxoid; Myofibroblasts; Plexiform; Prognosis; Review; Stomach