title: Genetic "lnc"-age of noncoding RNAs to human disease.
abstract: The list of functions of long noncoding RNAs (lncRNAs) in human tissues is rapidly growing. To further underscore their critical role in human health, two reports in this issue of JCI associate altered expression of novel lncRNAs with the heritable syndromes HELLP and brachydactyly type E.
authors.affiliation: Department of Medicine and Genetics, The Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599-7295, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Troy
authors.forename: Norman E
authors.initials: NE
authors.lastname: Sharpless
mesh_terms: D000818:Animals; D059327:Brachydactyly; D002453:Cell Cycle / Q000235:genetics*; D002881:Chromosomes, Human, Pair 12; D002886:Chromosomes, Human, Pair 17; D005260:Female; D005786:Gene Expression Regulation; D030342:Genetic Diseases, Inborn; D056426:Genetic Loci; D017359:HELLP Syndrome; D006801:Humans; D008297:Male; D011247:Pregnancy; D062085:RNA, Long Noncoding; D014178:Translocation, Genetic; D014327:Trophoblasts / Q000378:metabolism*
chemical_list: D062085:RNA, Long Noncoding