title: Ovarian granulosa cell tumor: An uncommon presentation with primary amenorrhea and virilization in a pubertal girl.
abstract: A 16-year-old girl presented with primary amenorrhea and excess hair growth on her body and face for the last three years, along with pain and a mass in her lower abdomen for last one year. Examination revealed hirsutism and other virilizing features, with an irregular mass in the lower abdomen corresponding to 16 weeks'gestation. Serum testosterone was 320 ng / dl and ultrasonogram of the pelvis revealed a solid mass of 5 × 4 cm in the left adnexa. Suspecting it to be a virilizing tumor of the left ovary, the patient was subjected to staging laparotomy, which revealed stage 1a ovarian involvement amenable to surgical resection alone. Histopathological examination confirmed the diagnosis of granulosa cell tumor of the ovary. Postoperatively the serum testosterone returned to 40 ng / dl and her menstrual cycle started after two months of surgery.
authors.affiliation: Department of Endocrinology, Medwin Hospital, Hyderabad, Andhra Pradesh, India.
authors.forename: Sunil Kumar
authors.initials: SK
authors.lastname: Kota
authors.forename: Kotni
authors.initials: K
authors.lastname: Gayatri
authors.forename: Jaya Prakash
authors.initials: JP
authors.lastname: Pani
authors.forename: Lalit Kumar
authors.initials: LK
authors.lastname: Meher
authors.forename: Siva Krishna
authors.initials: SK
authors.lastname: Kota
authors.forename: Kirtikumar D
authors.initials: KD
authors.lastname: Modi
keywords: Granulosa cell tumor; hirsutism; primary amenorrhea; virilization