title: Solubility and apical sealing characteristics of a new calcium silicate-based root canal sealer in comparison to calcium hydroxide-, methacrylate resin- and epoxy resin-based sealers.
abstract: OBJECTIVE
  To assess and compare the water sorption, solubility and apical sealing ability of iRoot SP and three other widely used root canal sealers.
  
  
  METHODS
  Solubility was assessed by immersing standardized samples of calcium silicate- (iRoot SP), calcium hydroxide- (Sealapex), methacrylate resin- (EndoREZ) and epoxy resin- (AH Plus) based sealers in distilled water and measuring weight gain and weight loss at 6 h, 24 h and daily for 14 days. Roots of extracted mandibular premolars (n = 80) were prepared with 0.04-taper nickel-titanium rotary files to a final size 40. Roots were then randomly divided into four experimental groups (n = 18) and two control groups (n = 4), root canal sealers were applied and apical leakage was assessed using the fluid filtration method. Data was analyzed using Kruskal Wallis analysis of variance and Mann-Whitney U-tests, with the level of significance set at p ≤ 0.05.
  
  
  RESULTS
  EndoREZ exhibited the highest water sorption, followed by iRoot SP, Sealapex and AH Plus. Sealapex exhibited significantly higher solubility than the other sealers, whereas no significant differences in solubility levels were observed between the other three sealers tested. AH Plus exhibited significantly lower microleakage than Sealapex and EndoREZ, whereas no difference in microleakage was found between AH Plus and iRoot SP.
  
  
  CONCLUSIONS
  In view of the study findings, all tested sealers except Sealapex met the ANSI/ADA's requirements for solubility and no difference was found between AH Plus and iRoot SP in terms of apical sealing ability.
authors.affiliation: Department of Endodontics, Center for Dental Sciences, Gulhane School of Medicine, Ankara, Turkey.
authors.forename: Seyda
authors.initials: S
authors.lastname: Ersahan
authors.forename: Cumhur
authors.initials: C
authors.lastname: Aydin
mesh_terms: D017610:Calcium Compounds / Q000008:administration & dosage / Q000737:chemistry*; D002126:Calcium Hydroxide / Q000008:administration & dosage / Q000737:chemistry*; D016022:Case-Control Studies; D004853:Epoxy Resins / Q000737:chemistry*; D008689:Methacrylates / Q000008:administration & dosage / Q000737:chemistry*; D012387:Root Canal Filling Materials; D017640:Silicates / Q000008:administration & dosage / Q000737:chemistry*; D012995:Solubility
chemical_list: D017610:Calcium Compounds; D004853:Epoxy Resins; D008689:Methacrylates; D012387:Root Canal Filling Materials; D017640:Silicates; D002126:Calcium Hydroxide; C031293:calcium silicate