title: Two new lignans from the stems of Schisandra bicolor.
abstract: Two new lignans, named zuihonins E (1) and F (2), were isolated from the stems of Schisandra bicolor Cheng var. tuberculata Law. The structures of the new lignans were elucidated on the basis of extensive spectroscopic analysis, including 1D, 2D NMR, and MS experiments, and their absolute stereochemistry was determined by circular dichroism spectrum. Compounds 1 and 2 did not inhibit the growth of hepatoma carcinoma cell (HepG2), lung carcinoma cell (A549), and human breast carcinoma (MCF-7) cell lines.
authors.affiliation: Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China. huang_riming@hotmail.com
authors.forename: Ri-Ming
authors.initials: RM
authors.lastname: Huang
authors.forename: Hui-Juan
authors.initials: HJ
authors.lastname: Huang
authors.forename: Nen-Ling
authors.initials: NL
authors.lastname: Zhang
authors.forename: Yue-Hui
authors.initials: YH
authors.lastname: Zhu
authors.forename: Xiao-Fei
authors.initials: XF
authors.lastname: Jiang
authors.forename: Zhi-Wei
authors.initials: ZW
authors.lastname: Su
authors.forename: Jian-Xiang
authors.initials: JX
authors.lastname: Yang
authors.forename: Zhi-Fang
authors.initials: ZF
authors.lastname: Xu
authors.forename: Chuan-Rong
authors.initials: CR
authors.lastname: Li
authors.forename: Samuel X
authors.initials: SX
authors.lastname: Qiu
mesh_terms: D004354:Drug Screening Assays, Antitumor; D005260:Female; D056945:Hep G2 Cells; D006801:Humans; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018547:Plant Stems / Q000737:chemistry; D032141:Schisandra / Q000737:chemistry*
chemical_list: D017705:Lignans; C578205:zuihonin E; C578206:zuihonin F