title: A molecular assay of tumor radiosensitivity: a roadmap towards biology-based personalized radiation therapy.
abstract: The last two decades have seen technological developments that have led to more accurate delivery of radiation therapy (RT), which has resulted in clinical gains in many solid tumors. However, a fundamental question and perhaps the next major hurdle is whether biological strategies can be developed to further enhance the effectiveness and efficiency of RT. This article addresses the development of a novel genomics-based molecular assay to predict tumor radiosensitivity, and proposes that this assay may prove pivotal in the development of biologically guided RT.
authors.affiliation: Department of Experimental Therapeutics & Radiation Oncology, Moffitt Cancer Center & Research Institute, Tampa, FL, USA, Tel.: +1 813 745 1824.
authors.forename: Javier F
authors.initials: JF
authors.lastname: Torres-Roca