title: HIV infection and osteoporosis: pathophysiology, diagnosis, and treatment options.
abstract: As the population with HIV continues to age, specialists in HIV care are increasingly encountering chronic health conditions, which now include osteoporosis, osteopenia, and fragility fractures. The pathophysiology of the bone effects of HIV infection is complex and includes traditional risk factors for bone loss as well as specific effects due to the virus itself, chronic inflammation, and HAART. Examining risk factors for low bone density and screening of certain patients is suggested, and consideration should be given to treatment for those considered high risk for fracture.
authors.affiliation: Department of Medicine, Endocrinology Diabetes and Metabolism, University of Colorado School of Medicine, Aurora, 80045, USA. Micol.Rothman@ucdenver.edu
authors.forename: Micol S
authors.initials: MS
authors.lastname: Rothman
authors.forename: Mary T
authors.initials: MT
authors.lastname: Bessesen
mesh_terms: D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects*; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D015658:HIV Infections / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D015994:Incidence; D010024:Osteoporosis / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology / Q000503:physiopathology*; D058866:Osteoporotic Fractures / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000517:prevention & control; D015995:Prevalence; D012307:Risk Factors
chemical_list: D050071:Bone Density Conservation Agents