title: Three new flavonoids from the seeds of Hippophae rhamnoides subsp. sinensis.
abstract: To study the chemical constituents of the seeds of Hippophae rhamnoides subsp. sinensis, three new flavonoids acylated with one monoterpenic acid, named 3-O-β-D-glucosyl-kaempferol-7-O-{2-O-[2(E)-2,6-dimethyl-6-hydroxy-2,7-octadienoyl]}-α-L-rhamnoside (3), 3-O-β-D-sophorosyl-kaempferol-7-O-{3-O-[2(E)-2,6-dimethyl-6-hydroxy-2,7-octadienoyl]}-α-L-rhamnoside (4), and 3-O-β-D-sophorosyl-kaempferol-7-O-{2-O-[2(E)-2,6-dimethyl-6-hydroxy-2,7-octadienoyl]}-α-L-rhamnoside (5), together with four known compounds, were isolated from the seeds of H. rhamnoides subsp. sinensis. Compounds 1 and 2 are reported for the first time from this genus. Their structures were elucidated on the basis of chemical and spectral analysis, including 1D and 2D NMR and HR-MS, and by comparison with literature data.
authors.affiliation: State Key Laboratory of New Drug & Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, Shanghai 200040, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.forename: Wen
authors.initials: W
authors.lastname: Gao
authors.forename: Min-Sheng
authors.initials: MS
authors.lastname: Cao
authors.forename: De-Yun
authors.initials: DY
authors.lastname: Kong
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D031281:Hippophae / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D012639:Seeds / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: C578207:3-O-beta-D-glucosyl-kaempferol-7-O-(2-O-(2(E)-2,6-dimethyl-6-hydroxy-2,7-octadienoyl))-alpha-L-rhamnoside; C578209:3-O-beta-D-sophorosyl-kaempferol-7-O-(2-O-(2(E)-2,6-dimethyl-6-hydroxy-2,7-octadienoyl))-alpha-L-rhamnoside; C578208:3-O-beta-D-sophorosyl-kaempferol-7-O-(3-O-(2(E)-2,6-dimethyl-6-hydroxy-2,7-octadienoyl))-alpha-L-rhamnoside; D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D006027:Glycosides