title: Cobalt(II)-catalyzed 1,4-addition of organoboronic acids to activated alkenes: an application to highly cis-stereoselective synthesis of aminoindane carboxylic acid derivatives.
abstract: It all adds up: The 1,4-addition of organoboronic acids to activated alkenes catalyzed by [Co(dppe)Cl(2)] is described. A [3+2]-annulation reaction of ortho-iminoarylboronic acids with acrylates to give various aminoindane carboxylic acid derivatives with cis-stereoselectivity is also demonstrated (see scheme; dppe = 1,2-bis(diphenylphosphino)ethane).
authors.affiliation: Department of Chemistry, National Tsing Hua University, Hsinchu, 30013, Taiwan.
authors.forename: Min-Hsien
authors.initials: MH
authors.lastname: Chen
authors.forename: Subramaniyan
authors.initials: S
authors.lastname: Mannathan
authors.forename: Pao-Shun
authors.initials: PS
authors.lastname: Lin
authors.forename: Chien-Hong
authors.initials: CH
authors.lastname: Cheng
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D002264:Carboxylic Acids / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D007189:Indans / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D001897:Boronic Acids; D002264:Carboxylic Acids; D007189:Indans; D009942:Organometallic Compounds; D003035:Cobalt