title: Cutaneous mastocytosis extending beyond a radiotherapy site: a form of radiodermatitis or a neoplastic phenomenon?
abstract: Ionising radiation is often used as an adjuvant in the management of breast cancer. Acute and chronic skin changes are well recognised complications associated with its use. We demonstrate a rare clinical presentation of cutaneous mastocytosis that occurred at the site of radiotherapy and then extended beyond this boundary, and ask whether this can be treated as a localised side effect of radiotherapy or whether the potential for systemic mastocytosis needs to be excluded.
authors.affiliation: Dermatology Department, Mater Adult Hospital, South Brisbane, Queensland, Australia.
authors.forename: Samantha J
authors.initials: SJ
authors.lastname: Davidson
authors.forename: Dougal
authors.initials: D
authors.lastname: Coates
mesh_terms: D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D011855:Radiodermatitis / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects; D014582:Urticaria Pigmentosa / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*
chemical_list: D006633:Histamine Antagonists
keywords: cutaneous mastocytosis; radiodermatitis; systemic mastocytosis