title: Association of adipokines and adhesion molecules with indicators of obesity in women undergoing mammography screening.
abstract: BACKGROUND
  The soluble cell adhesion molecules and adipokines are elevated in patients with obesity, hypertension, type 2 diabetes mellitus, breast cancer and atherosclerosis.
  
  
  OBJECTIVE
  To investigate the relationship between anthropometric profile, dietary intake, lipid profile and fasting glycemia with serum levels of adipokines (adiponectin and PAI-1) and adhesion molecules (ICAM-1 and VCAM-1) in women without breast cancer undergoing routine mammographic screening.
  
  
  METHODS
  Transversal study.
  
  
  METHODS
  One hundred and forty-five women over 40-years old participated in this study.
  
  
  RESULTS
  In 39.3% of cases the BMI was above 30 kg/m2; 46.9% had hypertension, 14.5% had type 2 Diabetes Mellitus, 31.7% had dyslipidemia and 88.3% presented a waist-to-hip ratio ≥ 0.8. A linear correlation was found between serum levels of PAI-1 and triglycerides, between serum levels of PAI-1 and WHR and between serum levels of VCAM-1 and BMI.
  
  
  CONCLUSIONS
  We found a high prevalence of obesity and metabolic syndrome. PAI-1 and VCAM-1 levels were correlated with clinical indicators of obesity and overweight.
authors.affiliation: Programa de Pós Graduação em Medicina: Ciências Médicas, Universidade Federal do Rio Grande do Sul (UFRGS), Rio Grande do Sul, Brasil. dornellesrosa@hotmail.com.
authors.forename: Caroline
authors.initials: C
authors.lastname: Isoppo de Souza
authors.forename: Daniela Dornelles
authors.initials: DD
authors.lastname: Rosa
authors.forename: Betina
authors.initials: B
authors.lastname: Ettrich
authors.forename: Gabriela Hermann
authors.initials: GH
authors.lastname: Cibeira
authors.forename: Juliana
authors.initials: J
authors.lastname: Giacomazzi
authors.forename: Paloma
authors.initials: P
authors.lastname: Tusset
authors.forename: Patrícia
authors.initials: P
authors.lastname: Ashton-Prolla
authors.forename: Lidia Rosi
authors.initials: LR
authors.lastname: Medeiros
authors.forename: Maira
authors.initials: M
authors.lastname: Caleffi
authors.forename: Eurico Camargo
authors.initials: EC
authors.lastname: Neto
authors.forename: Emilio Hideyuki
authors.initials: EH
authors.lastname: Moriguchi
authors.forename: Marcia Silveira
authors.initials: MS
authors.lastname: Graudenz