title: [Molecular-biological properties of the rubella virus strains isolated in St. Petersburg].
abstract: In the surveillance of rubella in the northwest region of Russia samples of nasopharyngeal swabs from 37 patients with rubella, which were treated in the 442nd district military hospital named after Z.P. Solovyov in autumn 2007 were screened for the rubella virus using RK-13 cell line, 22 strains of rubella virus were isolated. Gene sequencing of E1 region of rubella virus isolates was carried out. Rubella virus strains isolated in St. Petersburg during the 2007 outbreak belonged to rubella virus genotype 1E. The morphogenesis of RK-13 cells with formation of replication complexes and enveloped virions of rubella virus was shown.
authors.forename: Zh V
authors.initials: ZhV
authors.lastname: Buzitskaia
authors.forename: A K
authors.initials: AK
authors.lastname: Sirotkin
authors.forename: T M
authors.initials: TM
authors.lastname: Gudkova
authors.forename: A P
authors.initials: AP
authors.lastname: Prochukhanova
authors.forename: A V
authors.initials: AV
authors.lastname: Karpov
authors.forename: L M
authors.initials: LM
authors.lastname: Tsybalova
authors.forename: O I
authors.initials: OI
authors.lastname: Kiselev
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002460:Cell Line; D004196:Disease Outbreaks; D004847:Epithelial Cells / Q000473:pathology / Q000821:virology*; D006772:Hospitals, Military; D006801:Humans; D008297:Male; D009305:Nasopharynx / Q000473:pathology* / Q000821:virology; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D011817:Rabbits; D012409:Rubella / Q000175:diagnosis* / Q000453:epidemiology; D012412:Rubella virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D012426:Russia / Q000453:epidemiology; D014759:Viral Envelope Proteins / Q000235:genetics* / Q000378:metabolism; D055815:Young Adult
chemical_list: D014759:Viral Envelope Proteins; C061826:E1 envelope protein, Rubella virus