title: [Therapeutic hypothermia and management of sudden death].
abstract: Due to its protective effects on the brain and potentially the myocardium, cooling therapy is clearly part of the standard of care of any sudden death especially in the setting of myocardial infarction. Recent guidelines recommend cooling therapy (32 to 34 °C) for 12 to 24 hours in unconscious patients with spontaneous circulation after resuscitated sudden death. We provide here a review of clinical evidence, cooling techniques and potential adverse effects of cooling therapy.
authors.affiliation: Unité des soins intensifs de cardiologie, centre hémodynamique, clinique de cardiologie, centre hospitalier régional et universitaire de Lille, boulevard du Pr-Jules-Leclercq, 59037 Lille cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Delhaye
authors.forename: G
authors.initials: G
authors.lastname: Lemesle
mesh_terms: D016757:Death, Sudden, Cardiac / Q000209:etiology; D006323:Heart Arrest / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D007036:Hypothermia, Induced / Q000009:adverse effects / Q000379:methods; D015201:Meta-Analysis as Topic; D009203:Myocardial Infarction / Q000150:complications*; D017410:Practice Guidelines as Topic; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome