title: Chiral surfactant-type catalyst for asymmetric reduction of aliphatic ketones in water.
abstract: A novel chiral surfactant-type catalyst is developed. Micelles formed in water by association of the catalysts themselves, and this was confirmed by TEM analyses. Asymmetric transfer hydrogenation of aliphatic ketones catalyzed by the chiral metallomicellar catalyst gave good to excellent conversions and remarkable stereoselectivities (up to 95% ee). Synergistic effects between the metal-catalyzed center and the hydrophobic microenvironment of the core in the metallomicelle led to high enantioselectivities.
authors.affiliation: Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, China.
authors.forename: Jiahong
authors.initials: J
authors.lastname: Li
authors.forename: Yuanfu
authors.initials: Y
authors.lastname: Tang
authors.forename: Qiwei
authors.initials: Q
authors.lastname: Wang
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Li
authors.forename: Linfeng
authors.initials: L
authors.lastname: Cun
authors.forename: Xiaomei
authors.initials: X
authors.lastname: Zhang
authors.forename: Jin
authors.initials: J
authors.lastname: Zhu
authors.forename: Liangchun
authors.initials: L
authors.lastname: Li
authors.forename: Jingen
authors.initials: J
authors.lastname: Deng
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D008024:Ligands; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D012238:Rhodium / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry*; D013696:Temperature; D014867:Water / Q000737:chemistry*
chemical_list: D000438:Alcohols; D007659:Ketones; D008024:Ligands; D009942:Organometallic Compounds; D013501:Surface-Active Agents; D014867:Water; D012238:Rhodium