title: Preventing a paradigm shift: a plea for the computational genome.
abstract: Against the opinion that DNA as program is not sufficiently explanatory, we maintain that the cellular machinery is entirely computational, and we identify the crucial notion of the interpreter that expresses the gene with the minimal gene set. Epigenetics research does not so much need paradigm shifts as the unraveling of an exceedingly complex computational machine.
authors.affiliation: Dipartimento di Scienze mediche preventive, Università di Napoli Federico II, 80138 Naples, Italy. carmine.garzillo@unina.it
authors.forename: Carmine
authors.initials: C
authors.lastname: Garzillo
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Trautteur
mesh_terms: D005260:Female; D005824:Genetics, Behavioral; D023281:Genomics; D006801:Humans; D011247:Pregnancy