title: Nutritional assessment of hospitalized HIV-infected patients by the phase angle z-score measurement.
abstract: BACKGROUND
  This study analyzed the phase-angle (PA) values of hospitalized HVI-infected patients by comparing them with those reported for a healthy population and investigated their relation with nutritional parameters.
  
  
  METHODS
  This is a cross-sectional study including 101 hospitalized patients diagnosed with HIV infection and evaluated by bioimpedance, anthropometry and biochemical tests. The phase angle values, weight loss percentage (%WL), body mass index (BMI), arm muscle circumference (AMC), tricipital skinfold (TSF), body fat percentage (%BF) and albumin were considered. In order to compare with values for the healthy population, the PA z-score of the patients under study was calculated. Spearman's correlation and the multiple linear regression model were used to identify nutritional parameters associated with the PA z-score.
  
  
  RESULTS
  The patients showed a mean PA z-score of -2.6 ± 1.5, and only 6.6% of them with a positive value. The PA z-score values correlated with %WL (r = -0.51; p < 0.0001), albumin (r = 0.49; p < 0.0001), BMI (r = 0.58; p < 0.0001), AMC (r = 0.41; p < 0.0001), TSF (r = 0.47; p < 0.001) and %BF (r = 0.48, p < 0.0001). In multiple analysis %WL (p = 0.008), albumin (p = 0.01), AMC (p < 0.0001) and %BF (p = 0.0003) remained associated with the score.
  
  
  CONCLUSIONS
  Low PA z-score values were observed, suggesting a worse clinical prognosis for the patients. The inclusion of the PA z-score as a nutritional indicator during care provision to HIV-infected patients is recommended.
authors.affiliation: Departamento de Clínica Médica, Botucatu School of Medicine, São Paulo State University (UNESP), Brazil. alineantunes00@gmail.com
authors.forename: A
authors.initials: A
authors.lastname: Araujo Antunes
authors.forename: A P
authors.initials: AP
authors.lastname: Alves Pereira Rodrigues
authors.forename: J
authors.initials: J
authors.lastname: Geraix
authors.forename: L
authors.initials: L
authors.lastname: Vaz de Arruda Silveira
authors.forename: P
authors.initials: P
authors.lastname: Câmara Marques Pereira
authors.forename: Ma A
authors.initials: MA
authors.lastname: Barros Leite Carvalhaes
mesh_terms: D000328:Adult; D000886:Anthropometry; D023241:Antiretroviral Therapy, Highly Active; D050218:Body Fat Distribution; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D003627:Data Interpretation, Statistical; D005260:Female; D015658:HIV Infections / Q000503:physiopathology*; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D011379:Prognosis; D012044:Regression Analysis