title: Spontaneously formed semipermeable organic-inorganic hybrid vesicles permitting molecular weight selective transmembrane passage.
abstract: Semipermeable organic-inorganic hybrid vesicles coated with a siloxane surface were spontaneously formed by simple dispersion of an organoalkoxysilane lipid in water. The hybrid vesicles allow the permeation of hydrophilic small molecules across the membrane without an introduction of a pore-forming protein.
authors.affiliation: Graduate School of Materials Science, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 6300192, Japan. yasuhara@ms.naist.jp
authors.forename: Kazuma
authors.initials: K
authors.lastname: Yasuhara
authors.forename: Takahiro
authors.initials: T
authors.lastname: Kawataki
authors.forename: Shizuyo
authors.initials: S
authors.lastname: Okuda
authors.forename: Shohei
authors.initials: S
authors.lastname: Oshima
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kikuchi
mesh_terms: D000409:Alanine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D057927:Hydrophobic and Hydrophilic Interactions; D008567:Membranes, Artificial; D008970:Molecular Weight; D010539:Permeability; D012833:Siloxanes / Q000737:chemistry*
chemical_list: D008567:Membranes, Artificial; D012833:Siloxanes; D000409:Alanine