title: Introducing Drugster: a comprehensive and fully integrated drug design, lead and structure optimization toolkit.
abstract: CONCLUSIONS
  Drugster is a fully interactive pipeline designed to break the command line barrier and introduce a new user-friendly environment to perform drug design, lead and structure optimization experiments through an efficient combination of the PDB2PQR, Ligbuilder, Gromacs and Dock suites. Our platform features a novel workflow that guides the user through each logical step of the iterative 3D structural optimization setup and drug design process, by providing a seamless interface to all incorporated packages.
  
  
  BACKGROUND
  Drugster can be freely downloaded via our dedicated server system at http://www.bioacademy.gr/bioinformatics/drugster/.
authors.affiliation: Bioinformatics and Medical Informatics Team, Biomedical Research Foundation, Academy of Athens, Athens, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Vlachakis
authors.forename: Dimosthenis
authors.initials: D
authors.lastname: Tsagrasoulis
authors.forename: Vasileios
authors.initials: V
authors.lastname: Megalooikonomou
authors.forename: Sophia
authors.initials: S
authors.lastname: Kossida
mesh_terms: D015195:Drug Design; D008024:Ligands; D004364:Pharmaceutical Preparations / Q000737:chemistry; D012984:Software; D014584:User-Computer Interface
chemical_list: D008024:Ligands; D004364:Pharmaceutical Preparations