title: Leiomyosarcoma of the inferior nasal concha: a case report and literature review.
abstract: Leiomyosarcomas (LMSs) of the sinonasal tracts are rarely reported. We present a case of an LMS of the left inferior nasal concha, and discuss the management options with review of the literature. A 72-year-old female patient presented with epistaxis. Clinical examination and medical imaging showed a tumour arising from the left inferior nasal concha. An endoscopic resection was performed. Anatomopathological and immunohistochemical analyses revealed the tumour to be a grade 3 LMS with uncertain posterior margins. The patient was a Jehovah's Witness and refused more radical surgical resection due to religious beliefs; therefore, adjuvant conformal radiotherapy (60 Gy) was performed. LMS of the nasal cavity is a rare and locally aggressive tumour with a high tendency of recurrence, requiring radical surgical resection and long-term follow-up. The prognosis of a nasal cavity LMS is better than that of an LMS located in the paranasal sinuses.
authors.affiliation: ENT Department, CHU Charleroi, Charleroi, Belgium. chloe.dadesky@ulb.ac.be
authors.forename: C
authors.initials: C
authors.lastname: d'Adesky
authors.forename: J P
authors.initials: JP
authors.lastname: Duterme
authors.forename: D
authors.initials: D
authors.lastname: Lejeune
authors.forename: R
authors.initials: R
authors.lastname: Mehta
authors.forename: A
authors.initials: A
authors.lastname: Chaikh
authors.forename: P
authors.initials: P
authors.lastname: Castadot
authors.forename: J P
authors.initials: JP
authors.lastname: Duchateau
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000532:radiotherapy; D008279:Magnetic Resonance Imaging; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000532:radiotherapy; D020266:Radiotherapy, Conformal; D014057:Tomography, X-Ray Computed; D014420:Turbinates