title: The Unified Multiple System Atrophy Rating Scale: intrarater reliability.
abstract: BACKGROUND
  The Unified Multiple System Atrophy Rating Scale (UMSARS) was developed to provide a surrogate measure of disease progression in multiple system atrophy. In the present study, the intrarater agreement of the motor examination part of the UMSARS was determined.
  
  
  METHODS
  All patients were first examined face to face, while being video-recorded, by two senior and two junior investigators. The patients' videotaped examinations were reevaluated after 3 months. Intrarater reliability for each item was analyzed by kappa statistics.
  
  
  RESULTS
  Overall weighted kappa (κ) values were at least substantial or excellent for all UMSARS motor examination items, except for ocular motor dysfunction, which showed only moderate intrarater agreement. Intrarater reliability was comparable between senior and junior raters, with all κ differences being ≤ 0.22.
  
  
  CONCLUSIONS
  The motor examination part of the UMSARS was found to have satisfactory intrarater reliability in the present cohort.
authors.affiliation: Department of Neurology, Innsbruck Medical University, Innsbruck, Austria.
authors.forename: Florian
authors.initials: F
authors.lastname: Krismer
authors.forename: Klaus
authors.initials: K
authors.lastname: Seppi
authors.forename: François
authors.initials: F
authors.lastname: Tison
authors.forename: Cristina
authors.initials: C
authors.lastname: Sampaio
authors.forename: Anja
authors.initials: A
authors.lastname: Zangerl
authors.forename: Cecilia
authors.initials: C
authors.lastname: Peralta
authors.forename: Farid
authors.initials: F
authors.lastname: Yekhlef
authors.forename: Imad
authors.initials: I
authors.lastname: Ghorayeb
authors.forename: Fabienne
authors.initials: F
authors.lastname: Ory-Magne
authors.forename: Monique
authors.initials: M
authors.lastname: Galitzky
authors.forename: Maria
authors.initials: M
authors.lastname: Bozi
authors.forename: Tommaso
authors.initials: T
authors.lastname: Scaravilli
authors.forename: Carlo
authors.initials: C
authors.lastname: Colosimo
authors.forename: Felix
authors.initials: F
authors.lastname: Geser
authors.forename: Olivier
authors.initials: O
authors.lastname: Rascol
authors.forename: Werner
authors.initials: W
authors.lastname: Poewe
authors.forename: Niall P
authors.initials: NP
authors.lastname: Quinn
authors.forename: Gregor K
authors.initials: GK
authors.lastname: Wenning
mesh_terms: D000328:Adult; D000368:Aged; D004185:Disability Evaluation; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019578:Multiple System Atrophy / Q000175:diagnosis*; D009460:Neurologic Examination; D015203:Reproducibility of Results; D014741:Video Recording