title: Functional electrical stimulation for bladder, bowel, and sexual function.
abstract: The principles of using electrical stimulation of peripheral nerves or nerve roots for restoring useful bladder, bowel, and sexual function after damage or disease of the central nervous system are described. Activation of somatic or parasympathetic efferent nerves can produce contraction of striated or smooth muscle in the bladder, rectum, and sphincters. Activation of afferent nerves can produce reflex activation of somatic muscle and reflex inhibition or activation of smooth muscle in these organs. In clinical practice these techniques have been used to produce effective emptying of the bladder and bowel in patients with spinal cord injury and to improve continence of urine and feces. Stimulation of parasympathetic efferents can produce sustained erection of the penis, and stimulation of the nerves to the seminal vesicles can produce seminal emission. Reflex erection and ejaculation can also be produced by stimulation of afferent nerves. Experimental techniques for controlling emptying and continence by a single device, and prospects for comprehensive control of bladder, bowel, and sexual function by electrical techniques are described. These may include more selective electrodes, inactivation of nerves by specific stimulus parameters, greater use of sensors, and networking of implanted components connected to the central and peripheral nervous system.
authors.affiliation: Department of Neurosurgery, Stanford University, CA, USA. gcreasey@stanford.edu
authors.forename: Graham H
authors.initials: GH
authors.lastname: Creasey
authors.forename: Michael D
authors.initials: MD
authors.lastname: Craggs
mesh_terms: D004599:Electric Stimulation Therapy / Q000379:methods*; D005767:Gastrointestinal Diseases / Q000209:etiology / Q000628:therapy*; D006801:Humans; D010525:Peripheral Nerves / Q000502:physiology; D012735:Sexual Dysfunction, Physiological / Q000209:etiology / Q000628:therapy*; D013119:Spinal Cord Injuries / Q000150:complications / Q000628:therapy; D001745:Urinary Bladder Diseases / Q000209:etiology / Q000628:therapy*