title: [A case of cutaneous mammary re-irradiation].
abstract: In early-stage breast cancer, radiotherapy delivered after conservative surgery leads to a reduction in the risk of local recurrences by approximately two thirds. However, some local recurrences can occur in a previously irradiated region and be relevant for a second radiotherapy, exposing to an increased risk of adverse effects. We describe here the observation of a 66-year-old woman treated for a triple negative ductal infiltrative carcinoma of the left breast, who presented an early locoregional recurrence, notably as skin nodules, developed within the irradiated volume and progressing on chemotherapy. The patient was treated by re-irradiation performed concomitantly to oral chemotherapy by capecitabine.
authors.affiliation: Département de radiothérapie, institut Curie, Paris, France. julian.jacob28@gmail.com
authors.forename: J
authors.initials: J
authors.lastname: Jacob
authors.forename: J-Y
authors.initials: JY
authors.lastname: Pierga
authors.forename: V
authors.initials: V
authors.lastname: Fourchotte
authors.forename: Y M
authors.initials: YM
authors.lastname: Kirova
authors.forename: M-A
authors.initials: MA
authors.lastname: Bollet
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery / Q000628:therapy; D000069287:Capecitabine; D018270:Carcinoma, Ductal, Breast / Q000532:radiotherapy* / Q000628:therapy; D059248:Chemoradiotherapy; D003131:Combined Modality Therapy; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D018450:Disease Progression; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006801:Humans; D015182:Lymphatic Irradiation; D015412:Mastectomy, Segmental; D009364:Neoplasm Recurrence, Local / Q000628:therapy*; D012878:Skin Neoplasms / Q000628:therapy*
chemical_list: D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000069287:Capecitabine; D005472:Fluorouracil