title: [The role of markers of inflammation in assessment of prognosis in patients with ST-elevation myocardial infarction combined with disturbances of carbohydrate metabolism].
abstract: Diabetes mellitus (DM) is not only an independent risk factor (RF) of development of atherosclerosis, but it substantially worsens prognosis of patients with acute myocardial infarction (MI). Results of this study evidence that presence of disturbances of carbohydrate metabolism (DM or impaired glucose tolerance (IGT) in patients with ST elevation MI manifests with higher activity of the inflammatory process compared with patients with MI without abnormalities of carbohydrate metabolism. Unfavorable 1 year prognosis in patients with ST elevation MI is associated with higher concentrations of inflammation markers assessed on days 10-14 from onset of the disease: in patients with DM and IGT- of sCD40 ligand, in patients without disturbances of carbohydrate metabolism - C-reactive protein, in all patients irrespective of presence of carbohydrate metabolism abnormalities - interleukin 12.
authors.forename: V N
authors.initials: VN
authors.lastname: Karetnikova
authors.forename: O V
authors.initials: OV
authors.lastname: Gruzdeva
authors.forename: O L
authors.initials: OL
authors.lastname: Barbarash
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D002097:C-Reactive Protein / Q000378:metabolism; D002241:Carbohydrates / Q000097:blood*; D018450:Disease Progression; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007249:Inflammation / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000175:diagnosis / Q000401:mortality; D011379:Prognosis; D018570:Risk Assessment / Q000379:methods*; D012800:Siberia / Q000453:epidemiology; D015996:Survival Rate / Q000639:trends; D013997:Time Factors
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D002241:Carbohydrates; D002097:C-Reactive Protein