title: Iranian Azeri's Y-Chromosomal Diversity in the Context of Turkish-Speaking Populations of the Middle East.
abstract: BACKGROUND
  The main goal of this study was to conduct a comparative population genetic study of Turkish speaking Iranian Azeries as being the biggest ethno-linguistic community, based on the polymorph markers on Y chromosome.
  
  
  METHODS
  One hundred Turkish-speaking Azeri males from north-west Iran (Tabriz, 2008-2009) were selected based on living 3 generations paternally in the same region and not having any relationship with each other. Samples were collected by mouth swabs, DNA extracted and multiplex PCR done, then 12 Single Nucleotide Polymorphisms (SNPs) and 6 Microsatellites (MS) were sequenced. Obtained data were statistically analyzed by Arlequin software.
  
  
  RESULTS
  SNPs and Microsatellites typing were compared with neighboring Turkish-speaking populations (from Turkey and Azerbaijan) and Turkmens representing a possible source group who imposed the Turkish language during 11-15(th) centuries AD. Azeris demonstrated high level of gene diversity compatible with patterns registered in the neighboring Turkish-speaking populations, whereas the Turkmens displayed significantly lower level of genetic variation. This rate of genetic affiliation depends primarily on the geographic proximity.
  
  
  CONCLUSIONS
  The imposition of Turkish language to this region was realized predominantly by the process of elite dominance, i.e. by the limited number of invaders who left only weak patrilineal genetic trace in modern populations of the region.
authors.affiliation: Dept. of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran Iran.
authors.forename: L
authors.initials: L
authors.lastname: Andonian
authors.forename: S
authors.initials: S
authors.lastname: Rezaie
authors.forename: A
authors.initials: A
authors.lastname: Margaryan
authors.forename: Dd
authors.initials: D
authors.lastname: Farhud
authors.forename: K
authors.initials: K
authors.lastname: Mohammad
authors.forename: K Holakouie
authors.initials: KH
authors.lastname: Naieni
authors.forename: Mr
authors.initials: M
authors.lastname: Khorramizadeh
authors.forename: M H
authors.initials: MH
authors.lastname: Sanati
authors.forename: M
authors.initials: M
authors.lastname: Jamali
authors.forename: P
authors.initials: P
authors.lastname: Bayatian
authors.forename: L
authors.initials: L
authors.lastname: Yepiskoposyan
keywords: Iran; Iranian Azersi; Microsatellites; SNPs; Y chromosome diversity