title: Elaboration of natural polyfunctional preparations with antiparasitic and biostimulating properties for plant growing.
abstract: Producer of macrolide antibiotic avermectin Streptomyces avermitilis UCM Ac-2179 has been isolated from Ukrainian chernozem soil, its biosynthetic activity has been increased by the traditional selection and chemical mutagenesis methods. Streptomyces avermitilis UCM Ac-2179 synthesizes avermectin with the content of anti-parasitic B-components more than 40%. Addition of exogenous Na-pyruvate (1.5 mg/L) in cultural medium promotes a 2.5-fold augmentation of the avermectin synthesis. The preparation Avercom has been obtained by the method of ethanol extraction from the producer biomass. This preparation includes antibiotic avermectin and other biologically active substances: free amino acids, lipids, phytohormones. Avercom has high nematicidic activity and raises plant resistance to fungal and viral diseases. On the base of Avercom and plant growth regulators the complex preparations Actinolan and Ascoldia have been elaborated. The effectiveness of the biopreparations as nematicidic and plantstimulating means under experimental and industrial conditions was confirmed.
authors.affiliation: Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine 154 Acad Zabolotny Str, Kyiv, MSP D03680, Ukraine. galyna.iutynska@gmail.com
authors.forename: G O
authors.initials: GO
authors.lastname: Iutynska
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D000969:Antinematodal Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001042:Aphids / Q000187:drug effects / Q000502:physiology; D002851:Chromatography, High Pressure Liquid; D018553:Cucumis sativus / Q000187:drug effects / Q000254:growth & development / Q000382:microbiology / Q000469:parasitology; D003470:Culture Media; D005670:Fusarium / Q000187:drug effects / Q000502:physiology; D007306:Insecticides / Q000302:isolation & purification* / Q000494:pharmacology; D007559:Ivermectin / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000494:pharmacology; D010935:Plant Diseases / Q000382:microbiology / Q000469:parasitology / Q000628:therapy; D010937:Plant Growth Regulators / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D011773:Pyruvates / Q000494:pharmacology; D012987:Soil; D012988:Soil Microbiology; D013302:Streptomyces / Q000254:growth & development / Q000378:metabolism*; D014908:Triticum / Q000187:drug effects / Q000254:growth & development / Q000382:microbiology / Q000469:parasitology; D014431:Tylenchoidea / Q000187:drug effects / Q000502:physiology; D014455:Ukraine
chemical_list: D000596:Amino Acids; D000900:Anti-Bacterial Agents; D000969:Antinematodal Agents; D003470:Culture Media; D007306:Insecticides; D010937:Plant Growth Regulators; D011773:Pyruvates; D012987:Soil; D007559:Ivermectin; C019264:avermectin