title: Successful coronary artery bypass in Ehlers-Danlos type IV syndrome case report and review of the literature.
abstract: Atherosclerotic coronary artery occlusive disease is very rare in cases of Ehlers-Danlos type IV syndrome. We report what we believe is a unique case of successful coronary artery bypass grafting for atherosclerotic coronary artery disease in a patient with this syndrome and examine the possible implications for the natural progression of the disease through a review of the literature. Nevertheless, we reiterate previous investigators' advice that any invasive procedure on these patients should be approached with extreme caution and that surgery should be performed as a last resort, considering the significantly elevated risks.
authors.affiliation: Department of Cardiac Surgery, Christiana Hospital, Christiana Care Health System, Newark, Delaware 19718, USA. hsherif@christianacare.org
authors.forename: Hisham M F
authors.initials: HM
authors.lastname: Sherif
authors.forename: Ray A
authors.initials: RA
authors.lastname: Blackwell
mesh_terms: D000293:Adolescent; D000328:Adult; D000784:Aortic Dissection / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D003323:Coronary Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D017023:Coronary Angiography / Q000379:methods; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D004535:Ehlers-Danlos Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Adult; Ehlers-Danlos syndrome/classification/genetics/surgery; atherosclerosis; coronary artery disease; coronary artery surgery; genetic predisposition to disease; male; vascular diseases/etiology