title: [Poorly controlled asthma: diagnosis and therapeutics in children and adolescents].
abstract: Asthma is one of the most common chronic diseases in children. While most children with asthma respond to low doses of inhaled corticosteroids and /or leukotriene receptor antagonists, some of them remain symptomatic regardless of any therapeutic effort, showing a high morbidity and even mortality. While most of the patients control symptoms adequately, there is a large group with severe symptoms of the disease and difficult to control. The aim of this review is to discuss the clinical aspects, diagnosis and treatment of poorly controlled asthma in children and adolescents and its implications in daily clinical practice.
authors.affiliation: Hospital de Niños Orlando Alassia, Santa Fe, Argentina. hugoneffen@arnet.com.ar
authors.forename: Hugo
authors.initials: H
authors.lastname: Neffen
authors.forename: Santiago
authors.initials: S
authors.lastname: Vidaurreta
authors.forename: Ana
authors.initials: A
authors.lastname: Balanzat
authors.forename: Mónica Silvia
authors.initials: MS
authors.lastname: De Gennaro
authors.forename: Verónica
authors.initials: V
authors.lastname: Giubergia
authors.forename: Jorge F
authors.initials: JF
authors.lastname: Maspero
authors.forename: Ricardo J
authors.initials: RJ
authors.lastname: Saranz
authors.forename: Alejandro M
authors.initials: AM
authors.lastname: Teper
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use; D000888:Antibodies, Anti-Idiotypic / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis* / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D015897:Comorbidity; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D000069444:Omalizumab
chemical_list: D000305:Adrenal Cortex Hormones; D018927:Anti-Asthmatic Agents; D000888:Antibodies, Anti-Idiotypic; D061067:Antibodies, Monoclonal, Humanized; D000069444:Omalizumab