title: Three-component green reaction of arylaldehydes, 6-amino-1,3- dimethyluracil and active methylene compounds catalyzed by Zr(HSO4)4 under solvent-free conditions.
abstract: A convenient one-pot, three-component reaction of aromatic aldehydes, 6-amino-1,3-dimethyluracil and active methylene compounds in the presence of Zr(HSO4)4 as a heterogeneous catalyst, under solvent-free conditions brings a very simple and highly efficient method for the preparation of pyrimido[4,5-b]quinolines, pyrimido[5',4':5,6]pyrido[2,3- d]pyrimidines, indeno[2',1':5,6]pyrido[2,3-d]pyrimidines and a new class of pyrimidinedione derivatives in excellent yields. This approach is general and provides several advantages such as simple reaction set-up, very mild reaction conditions, high yields, recyclability of the catalyst and environmentally friendly benign.
authors.affiliation: Department of Chemistry, Faculty of Science, East Tehran Branch, Islamic Azad University, Tehran, Iran.
authors.forename: Shahrzad
authors.initials: S
authors.lastname: Abdolmohammadi
authors.forename: Saeed
authors.initials: S
authors.lastname: Balalaie
authors.forename: Mohammad
authors.initials: M
authors.lastname: Barari
authors.forename: Frank
authors.initials: F
authors.lastname: Rominger
mesh_terms: D000447:Aldehydes / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D055772:Green Chemistry Technology / Q000379:methods; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis / Q000737:chemistry; D008958:Models, Molecular; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry; D014498:Uracil / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D015040:Zirconium / Q000737:chemistry*
chemical_list: C479868:6-amino-1,3-dimethyl uracil; D000447:Aldehydes; D006841:Hydrocarbons, Aromatic; D011743:Pyrimidines; D011804:Quinolines; D014498:Uracil; D015040:Zirconium