title: Microsurgical management of non-neurofibromatosis spinal schwannoma.
abstract: BACKGROUND
  The aim of this study is to assess the clinical properties and surgical results of patients diagnosed with spinal schwannomas without neurofibromatosis (NF) properties.
  
  
  METHODS
  The data obtained from 35 patients who underwent resection of spinal schwannomas were analyzed. All cases with neurofibromas and those with a known diagnosis of NF Type 1 or 2 were excluded. 35 patients underwent surgery for spinal schwannoma at our institution between January 1997 and 2010. The data were gathered retrospectively from medical records and included clinical presentation, tumor location and post-operative complications. All cases were surgically excised, and they were confirmed to be schwannomas by pathologists with histopathological sections in paraffin stained with hematoxylin-eosin.
  
  
  RESULTS
  We treated 35 (20 males and 15 females) patients with spinal schwannomas. The mean age of the patients was 47.2 (between 13 and 76) years. Of the cases, six schwannomas were located in the cervical spine, four in the thoracic spine, two in cervico-thoracic area, 10 in the thoraco-lumbar area and 13 in the lumbar spine. Two patients had malignant schwannomas that were recurrent. Of the 35 cases, the schwannomas were intradural-extramedullary in 30 cases (86%), intradural-intramedullar in 2 cases (6%), and extradural in 3 cases (9%).
  
  
  CONCLUSIONS
  Spinal schwannomas may occur at any level of the spinal axis and are most frequently intradural-extramedullary. The most common clinical presentation is pain. Most of the spinal schwannomas in non-NF patients can be resected completely without or with minor post-operative deficits. This knowledge may help us to create a strategy for total resection of a spinal schwannomas.
authors.affiliation: Department of Neurosurgery, Tayfur Ata Sokmen Medical Faculty, Mustafa Kemal University, Hatay, Turkey. Electronic address: draltasmurat@yahoo.com.
authors.forename: Murat
authors.initials: M
authors.lastname: Altaş
authors.forename: Ajlan
authors.initials: A
authors.lastname: Cerçi
authors.forename: Gokalp
authors.initials: G
authors.lastname: Silav
authors.forename: Ramazan
authors.initials: R
authors.lastname: Sari
authors.forename: Kenan
authors.initials: K
authors.lastname: Coşkun
authors.forename: Naci
authors.initials: N
authors.lastname: Balak
authors.forename: Nejat
authors.initials: N
authors.lastname: Işik
authors.forename: Ilhan
authors.initials: I
authors.lastname: Elmaci
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008866:Microsurgery; D008875:Middle Aged; D009442:Neurilemmoma / Q000601:surgery*; D012189:Retrospective Studies; D013120:Spinal Cord Neoplasms / Q000601:surgery*; D055815:Young Adult
keywords: Columna vertebral; Neurofibromatosis; Schwannoma; Spine