title: Effect of the menstrual cycle on serum diamine oxidase levels in healthy women.
abstract: OBJECTIVE
  Serum diamine oxidase (DAO) level is employed as a useful marker of intestinal mucosal integrity. As reported previously, the range of serum DAO levels in women is wider than that in men. We hypothesized that the menstrual cycle may affect DAO levels.
  
  
  METHODS
  Thirty-six women of Japanese descent were recruited. All participants, aged 20-29 years, were healthy. Food surveys utilized in this study were based on questionnaires validated by dietitians. Complete blood counts, biochemical parameters, female hormones, and serum DAO levels during the follicular and luteal phases were measured in each subject.
  
  
  RESULTS
  Biochemical parameters, except for DAO levels, were comparable between the two phases. However, serum DAO levels during the luteal phase were significantly higher than those during the follicular phase.
  
  
  CONCLUSIONS
  Serum DAO levels were influenced by the menstrual cycle. Furthermore, our findings suggest that serum DAO levels should be interpreted cautiously in premenopausal women.
authors.affiliation: Department of Nutrition, Kobe University Hospital, Kobe University School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan. hamada@med.kobe-u.ac.jp
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Hamada
authors.forename: Yurika
authors.initials: Y
authors.lastname: Shinohara
authors.forename: Miyuki
authors.initials: M
authors.lastname: Yano
authors.forename: Mari
authors.initials: M
authors.lastname: Yamamoto
authors.forename: Misa
authors.initials: M
authors.lastname: Yoshio
authors.forename: Kumiko
authors.initials: K
authors.lastname: Satake
authors.forename: Akiyo
authors.initials: A
authors.lastname: Toda
authors.forename: Midori
authors.initials: M
authors.lastname: Hirai
authors.forename: Makoto
authors.initials: M
authors.lastname: Usami
mesh_terms: D000328:Adult; D006631:Amine Oxidase (Copper-Containing) / Q000097:blood*; D044466:Asian People; D001772:Blood Cell Count; D004435:Eating; D005260:Female; D005498:Follicular Phase / Q000097:blood; D006801:Humans; D008183:Luteal Phase / Q000097:blood; D008597:Menstrual Cycle / Q000097:blood*; D011374:Progesterone / Q000097:blood; D055815:Young Adult
chemical_list: D011374:Progesterone; D006631:Amine Oxidase (Copper-Containing)