title: Clostridium perfringens type A fatal acute hemorrhagic gastroenteritis in a dog.
abstract: The morning after participating in a dog show, a 2-year-old Pomeranian dog was found dead in a pool of bloody feces. Necropsy revealed hemorrhagic gastroenteritis of the entire gastrointestinal tract, with many Gram-positive bacilli on the surface and in the lumen and crypts of the intestine. Enterotoxin-positive type A Clostridium perfringens were isolated in large numbers. This dramatic case of fatal C. perfringens gastroenteritis highlights the need to better understand the role of this bacterium in enteric disease of dogs.
authors.affiliation: Department of Pathobiology (Schlegel, Prescott), University of Guelph, Guelph, Ontario N1G 2W1.
authors.forename: Ben J
authors.initials: BJ
authors.lastname: Schlegel
authors.forename: Tony
authors.initials: T
authors.lastname: Van Dreumel
authors.forename: Durda
authors.initials: D
authors.lastname: Slavić
authors.forename: John F
authors.initials: JF
authors.lastname: Prescott
mesh_terms: D000208:Acute Disease; D000818:Animals; D003015:Clostridium Infections / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D003016:Clostridium perfringens / Q000302:isolation & purification* / Q000472:pathogenicity; D004283:Dog Diseases / Q000175:diagnosis* / Q000382:microbiology; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D005759:Gastroenteritis / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis / Q000382:microbiology / Q000662:veterinary*; D007413:Intestinal Mucosa / Q000382:microbiology / Q000473:pathology