title: Exonuclease-aided amplification for label-free and fluorescence turn-on DNA detection based on aggregation-induced quenching.
abstract: A facile, universal and label-free fluorescence turn-on amplification strategy for the detection of DNA has been reported, which can achieve ultralow femtomolar detection of a target gene sequence with high selectivity.
authors.affiliation: State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Jilin, China.
authors.forename: Enguo
authors.initials: E
authors.lastname: Ju
authors.forename: Xinjian
authors.initials: X
authors.lastname: Yang
authors.forename: Youhui
authors.initials: Y
authors.lastname: Lin
authors.forename: Fang
authors.initials: F
authors.lastname: Pu
authors.forename: Jinsong
authors.initials: J
authors.lastname: Ren
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Qu
mesh_terms: D020137:Base Pair Mismatch; D004247:DNA / Q000032:analysis*; D005092:Exonucleases / Q000378:metabolism*; D005456:Fluorescent Dyes / Q000737:chemistry*; D007094:Imides / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D016159:Tumor Suppressor Protein p53 / Q000235:genetics
chemical_list: D005456:Fluorescent Dyes; D007094:Imides; D016159:Tumor Suppressor Protein p53; D004247:DNA; D005092:Exonucleases