title: Comparing the clinical profile of non obese children with sleep apnea and snoring.
abstract: Few studies in the literature have looked into the cardiovascular and metabolic effects of Obstructive Sleep Apnea Syndrome (OSAS) in children.
  
  
  OBJECTIVE
  This study aims to evaluate the metabolic profile of non-obese children with OSAS.
  
  
  METHODS
  Fifty-two children were enrolled in this study, 21 girls and 31 boys. Patients were divided into two groups: OSAS (28 children) and Snore (22 children) according to polysomnographic evaluation. All children were submitted to ENT examination, measurements of weight, height and blood pressure. Blood samples were tested for hemoglobin, hematocrit, fasting glucose, fasting insulin, triglycerides, total cholesterol, HDL, LDL, VLDL, TSH and T4. The gathered data sets were compared between groups and also within the OSAS group according to the severity of the syndrome.
  
  
  RESULTS
  The children from both groups had no alterations in blood pressure levels. The results of the blood tests were normal for both groups. Results of hemoglobin, hematocrit, and HDL were all significantly higher in the Snore group when compared to the OSAS group; by their turn, VLDL levels were higher in the OSAS group. There was no statistical difference between the groups based on OSAS severity.
  
  
  CONCLUSIONS
  Non-obese children with OSAS present no significant alterations in metabolic tests or blood pressure levels.
authors.affiliation: Federal University of São Paulo, SP.
authors.forename: Daniele de Oliveira Soares
authors.initials: Dde O
authors.lastname: Stefanini
authors.forename: Emília Leite de
authors.initials: EL
authors.lastname: Barros
authors.forename: Renato
authors.initials: R
authors.lastname: Stefanini
authors.forename: Márcia Lurdes de Cássia
authors.initials: ML
authors.lastname: Pradella-Hallinan
authors.forename: Shirley Shizue Nagata
authors.initials: SS
authors.lastname: Pignatari
authors.forename: Reginaldo Raimundo
authors.initials: RR
authors.lastname: Fujita
mesh_terms: D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D017286:Polysomnography; D012720:Severity of Illness Index; D020181:Sleep Apnea, Obstructive / Q000097:blood* / Q000503:physiopathology; D012913:Snoring / Q000097:blood* / Q000503:physiopathology
chemical_list: D015415:Biomarkers