title: Whole-exome sequencing reveals somatic mutations in HRAS and KRAS, which cause nevus sebaceus.
authors.affiliation: Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Jonathan L
authors.initials: JL
authors.lastname: Levinsohn
authors.affiliation: Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Li C
authors.initials: LC
authors.lastname: Tian
authors.affiliation: Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Lynn M
authors.initials: LM
authors.lastname: Boyden
authors.affiliation: Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: McNiff
authors.affiliation: Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Deepak
authors.initials: D
authors.lastname: Narayan
authors.affiliation: Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Erin S
authors.initials: ES
authors.lastname: Loring
authors.affiliation: Department of Dermatology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
authors.forename: Duri
authors.initials: D
authors.lastname: Yun
authors.affiliation: Departments of Dermatology and Family Medicine, University of California, San Francisco, San Francisco, California, USA.
authors.forename: Jeffrey L
authors.initials: JL
authors.lastname: Sugarman
authors.affiliation: Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA; Yale Center for Mendelian Genomics, New Haven, Connecticut, USA.
authors.forename: John D
authors.initials: JD
authors.lastname: Overton
authors.affiliation: Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA; Yale Center for Mendelian Genomics, New Haven, Connecticut, USA.
authors.forename: Shrikant M
authors.initials: SM
authors.lastname: Mane
authors.affiliation: Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, USA; Yale Center for Mendelian Genomics, New Haven, Connecticut, USA; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Richard P
authors.initials: RP
authors.lastname: Lifton
authors.affiliation: Department of Dermatology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
authors.forename: Amy S
authors.initials: AS
authors.lastname: Paller
authors.affiliation: Department of Dermatology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
authors.forename: Annette M
authors.initials: AM
authors.lastname: Wagner
authors.affiliation: Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Antaya
authors.affiliation: Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA. Electronic address: keith.choate@yale.edu.
authors.forename: Keith A
authors.initials: KA
authors.lastname: Choate
mesh_terms: D000293:Adolescent; D000328:Adult; D000595:Amino Acid Sequence; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D004817:Epidermis / Q000473:pathology; D059472:Exome / Q000235:genetics*; D006801:Humans; D007223:Infant; D008875:Middle Aged; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics*; D054000:Nevus, Sebaceous of Jadassohn / Q000235:genetics* / Q000473:pathology; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D016283:Proto-Oncogene Proteins p21(ras) / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000379:methods*; D055815:Young Adult; D018631:ras Proteins / Q000235:genetics*
chemical_list: C117307:KRAS protein, human; D011518:Proto-Oncogene Proteins; C501009:HRAS protein, human; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins