title: Palladium-catalyzed tandem reaction of o-aminophenols, bromoalkynes and isocyanides to give 4-amine-benzo[b][1,4]oxazepines.
abstract: A robust route to 4-amine-benzo[b][1,4]oxazepines relying upon a palladium-catalyzed tandem reaction of o-aminophenols, bromoalkynes and isocyanides has been developed. This chemistry presumably proceeds through the migratory insertion of isocyanides into the vinyl-palladium intermediate as a key step.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, China.
authors.forename: Bifu
authors.initials: B
authors.lastname: Liu
authors.forename: Yibiao
authors.initials: Y
authors.lastname: Li
authors.forename: Meizhou
authors.initials: M
authors.lastname: Yin
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000627:Aminophenols / Q000737:chemistry*; D002384:Catalysis; D003486:Cyanides / Q000737:chemistry*; D010077:Oxazepines / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D000627:Aminophenols; D003486:Cyanides; D010077:Oxazepines; C027667:2-aminophenol; D010165:Palladium