title: Coccidioidomycosis-associated Deaths, United States, 1990-2008.
abstract: Coccidioidomycosis is endemic to the Americas; however, data on deaths caused by this disease are limited. To determine the rate of coccidioidomycosis-associated deaths in the United States, we examined multiple cause-coded death records for 1990-2008 for demographics, secular trends, and geographic distribution. Deaths were identified by International Classification of Diseases, 9th and 10th Revision, codes, and mortality rates were calculated. Associations of deaths among persons with selected concurrent conditions were examined and compared with deaths among a control group who did not have coccidioidomycosis. During the 18-year period, 3,089 coccidioidomycosis-associated deaths occurred among US residents. The overall age-adjusted mortality rate was 0.59 per 1 million person-years; 55,264 potential life-years were lost. Those at highest risk for death were men, persons >65 years, Hispanics, Native Americans, and residents of California or Arizona. Common concurrent conditions were HIV and other immunosuppressive conditions. The number of deaths from coccidioidomycosis might be greater than currently appreciated.
authors.affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
authors.forename: Jennifer Y
authors.initials: JY
authors.lastname: Huang
authors.forename: Benjamin
authors.initials: B
authors.lastname: Bristow
authors.forename: Shira
authors.initials: S
authors.lastname: Shafir
authors.forename: Frank
authors.initials: F
authors.lastname: Sorvillo
mesh_terms: D000367:Age Factors; D003047:Coccidioidomycosis / Q000453:epidemiology / Q000266:history / Q000401:mortality*; D005260:Female; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008297:Male; D014481:United States / Q000453:epidemiology / Q000208:ethnology