title: First successful combined heart and kidney transplant in Iran: a case report.
abstract: Combined heart and kidney transplant has become an accepted therapy for patients with coexisting heart and kidney failure. This method, compared with single-organ transplant, has a better outcome. Here, we report the first successful combined heart and kidney transplant in Iran. The patient was a 36-year-old man with end-stage renal disease owing to IgA nephropathy, admitted to Masih Daneshvari Hospital in Tehran, Iran for progressive dyspnea and chest pain. In-patient evaluations revealed cardiomyopathy leading to end-stage heart failure. Owing to concurrent heart and kidney end-stage diseases, combined cardiorenal transplant was done. Eight months after his transplant, routine follow-ups have not shown any signs of acute rejection. He is now New York Heart Association functional class I. Both cardiac and renal functions are within normal ranges. Good outcome during follow-up for this case justifies simultaneous heart plus kidney transplants as an alternate treatment for patients with advanced disease of both organs.
authors.affiliation: From the Lung Transplantation Research Center, National Research Institute of Tuberculosis and Lung Disease, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Zargham-Hossein
authors.initials: ZH
authors.lastname: Ahmadi
authors.forename: Seyed Mohsen
authors.initials: SM
authors.lastname: Mirhosseini
authors.forename: Mohammad
authors.initials: M
authors.lastname: Fakhri
authors.forename: Amirhossein
authors.initials: A
authors.lastname: Mozaffary
authors.forename: Mojtaba
authors.initials: M
authors.lastname: Lotfaliany
authors.forename: Seyed Mohammad Reza
authors.initials: SM
authors.lastname: Nejatollahi
authors.forename: Seyed-Ali
authors.initials: SA
authors.lastname: Marashi
authors.forename: Neda
authors.initials: N
authors.lastname: Behzadnia
authors.forename: Babak
authors.initials: B
authors.lastname: Sharif-Kashani
mesh_terms: D000328:Adult; D009202:Cardiomyopathies / Q000150:complications / Q000175:diagnosis; D005922:Glomerulonephritis, IGA / Q000150:complications / Q000175:diagnosis; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D016027:Heart Transplantation; D006801:Humans; D007492:Iran; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D016030:Kidney Transplantation; D008297:Male; D013997:Time Factors; D016896:Treatment Outcome