title: Necrotizing soft-tissue infections in obstetric and gynecologic patients.
abstract: For the clinician, necrotizing soft-tissue infections have remained a daunting opponent since the first writings on the subject over 2000 years ago. Early disease may be incorrectly diagnosed as cellulitis, and this delay in correctly diagnosing and expeditiously proceeding to radical surgical debridement may lead to a high degree of mortality. Although several inciting events and risk factors have been described that allow for the development and progression of this disease, the diagnosis is still made clinically. Only aggressive surgical management in combination with broad-spectrum antibiotics will offer a chance at improving patient outcomes.
authors.affiliation: Department Ob/Gyn, UTHSC-Houston, Lyndon Baines Johnson Hospital, Houston, TX, USA. sebastian.faro@uth.tmc.edu
authors.forename: Sebastian
authors.initials: S
authors.lastname: Faro
authors.forename: Jonathan P
authors.initials: JP
authors.lastname: Faro
mesh_terms: D019115:Fasciitis, Necrotizing / Q000175:diagnosis* / Q000453:epidemiology* / Q000266:history / Q000382:microbiology / Q000628:therapy; D005260:Female; D049672:History, 19th Century; D049673:History, 20th Century; D049690:History, Ancient; D006801:Humans; D015994:Incidence; D011183:Postoperative Complications / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000628:therapy; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000628:therapy; D011645:Puerperal Infection / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000628:therapy; D012307:Risk Factors; D018461:Soft Tissue Infections / Q000175:diagnosis* / Q000453:epidemiology* / Q000382:microbiology / Q000628:therapy