title: Change in body compositions of Asian recipients after kidney transplantation.
abstract: Kidney transplantation and accompanying medical conditions may result in changes in body composition. Such changes have been evaluated in Caucasian recipients, but not in Asian recipients. Herein, we conducted a study on Asian recipients because Asians have a different body composition from Caucasians. A total of 50 Asian recipients was enrolled as a prospective cohort. Using bioelectrical impedance analysis, body composition (muscle and fat mass) was assessed after 2 weeks (baseline), and at 1, 3, 6, 9, and 12 months following kidney transplantation. To find predictors related to changes, the data were analyzed by multivariate analysis using forward selection. All of the patients had good graft function during the study period. Patients gained approximately 3 kg within 1 yr of kidney transplantation. The proportion of muscle mass significantly decreased (P(trend) = 0.001) and the proportion of fat mass significantly increased over time (P(trend) = 0.002). The multivariate results revealed that male recipients, deceased donor type, and low protein intake were associated with an increase in fat mass and a decrease in muscle mass. The results from this study may help to investigate differences in body composition changes between races, as well as the factors related to these changes.
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Seung Seok
authors.initials: SS
authors.lastname: Han
authors.forename: Jin Ho
authors.initials: JH
authors.lastname: Hwang
authors.forename: Yoon Jung
authors.initials: YJ
authors.lastname: Oh
authors.forename: Ran-hui
authors.initials: RH
authors.lastname: Cha
authors.forename: Curie
authors.initials: C
authors.lastname: Ahn
authors.forename: Yon Su
authors.initials: YS
authors.lastname: Kim
mesh_terms: D050154:Adiposity; D000328:Adult; D044466:Asian People; D001823:Body Composition; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011446:Prospective Studies; D013997:Time Factors; D044465:White People
keywords: Asian; Body Composition; Fat; Kidney Transplantation; Muscle