title: Surgical treatment of adult cholesteatoma: long-term follow-up using total reconstruction procedure without staging.
abstract: CONCLUSIONS
  A total of 330 cases of adult cholesteatoma were operated with canal-wall down (CWD) and total reconstruction procedure (TRP) without staging. Independent of preoperative middle ear conditions, cholesteatoma extent and localization, long-term improvement of hearing with a low incidence of residual and recurrent disease were achieved.
  
  
  OBJECTIVE
  To evaluate long-term surgical and hearing results using a well-defined surgical technique without staging in adult cholesteatoma.
  
  
  METHODS
  The same CWD surgical technique, including obliteration of the mastoid cavity, reconstruction of the canal wall, and ossiculoplasty with autologous bone, was used by three senior surgeons (1982-2004). Preoperative and postoperative pure tone average (PTA) for air conduction (AC), bone conduction (BC), and air-bone gap (ABG) were assessed and compared 1, 3, and 6 years after surgery. Various prognostic factors with potential influence on long-term hearing outcome were evaluated.
  
  
  RESULTS
  Recurrence of AC occurred in 10%, residual disease in 3%. Six years after surgery all patients except one had a dry ear and over 92% of all cases were water resistant. Three patients developed complete deafness. Long-lasting improvement and/or preservation of hearing, with maintenance of PTA-ABG closure in 68% of all cases within 20 dB, were obtained. Sixty-four (19%) ossicular revisions were performed.
authors.affiliation: Department of Otolaryngology, University Hospital Uppsala, Sweden. lennart.edfeldt@akademiska.se
authors.forename: Lennart
authors.initials: L
authors.lastname: Edfeldt
authors.forename: Karin
authors.initials: K
authors.lastname: Strömbäck
authors.forename: Anders
authors.initials: A
authors.lastname: Kinnefors
authors.forename: Helge
authors.initials: H
authors.lastname: Rask-Andersen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001301:Audiometry, Pure-Tone; D001844:Bone Conduction; D002648:Child; D002675:Child, Preschool; D018424:Cholesteatoma, Middle Ear / Q000150:complications / Q000473:pathology / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D034381:Hearing Loss / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019651:Plastic Surgery Procedures; D020127:Recovery of Function; D012086:Reoperation; D016896:Treatment Outcome; D055815:Young Adult