title: A convenient synthesis of anthranilic acids by Pd-catalyzed direct intermolecular ortho-C-H amidation of benzoic acids.
abstract: An efficient method for synthesis of anthranilic acids by Pd-catalyzed ortho-C-H amidation of benzoic acids is disclosed. The amidation is proposed to proceed by carboxylate-assisted ortho-C-H palladation to form an arylpalladium(II) complex, followed by nitrene insertion to the Pd-C bond.
authors.affiliation: State Key Laboratory for Chirosciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
authors.forename: Ka-Ho
authors.initials: KH
authors.lastname: Ng
authors.forename: Fo-Ning
authors.initials: FN
authors.lastname: Ng
authors.forename: Wing-Yiu
authors.initials: WY
authors.lastname: Yu
mesh_terms: D001565:Benzoates / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry; D010165:Palladium / Q000737:chemistry*; D062367:ortho-Aminobenzoates / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D001565:Benzoates; D056831:Coordination Complexes; D062367:ortho-Aminobenzoates; D010165:Palladium; D002244:Carbon; D006859:Hydrogen