title: [Cognitive deficit in schizophrenia: MATRICS Consensus Cognitive Battery].
abstract: Cognitive deficits constitute a core symptom in schizophrenia, are difficult to treat, and have special relevance regarding prognosis and functional outcome. The search for pharmacological strategies for improving cognition in schizophrenic patients has been hindered by the lack of a consensus regarding instruments for cognitive assessment. The 'Measurement and Treatment Research to Improve Cognition in Schizophrenia' (MATRICS) initiative of the U.S. National Institute of Mental Health (NIMH) set the development of a consensus cognitive battery as one of its objectives. In a first phase, the seven cognitive domains which have been shown to be impaired in schizophrenia and that were to be assessed were identified: Speed of processing, Attention/Vigilance, Working memory, Verbal learning, Visual learning, Reasoning and problem solving, and Social cognition. In a second phase, the MATRICS Consensus Cognitive Battery (MCCB) was developed. This is a cognitive assessment battery composed of ten instruments, which assess the seven domains in a little over one hour. The MCCB has been standardized in U.S. population, and the Spanish standardization has been recently published.
authors.affiliation: Servicio de Psiquiatría; Instituto de Investigación Hospital 12 de Octubre, i+12, Madrid, España. roberto.rodriguez.jimenez@gmail.com
authors.forename: Roberto
authors.initials: R
authors.lastname: Rodríguez-Jiménez
authors.forename: Alexandra
authors.initials: A
authors.lastname: Bagney
authors.forename: Marta
authors.initials: M
authors.lastname: Moreno-Ortega
authors.forename: Cristina
authors.initials: C
authors.lastname: García-Navarro
authors.forename: Ana Isabel
authors.initials: AI
authors.lastname: Aparicio
authors.forename: Raúl
authors.initials: R
authors.lastname: López-Antón
authors.forename: José
authors.initials: J
authors.lastname: de la Oliva
authors.forename: Miguel Ángel
authors.initials: MÁ
authors.lastname: Jiménez-Arriero
authors.forename: José Luis
authors.initials: JL
authors.lastname: Santos
authors.forename: Antonio
authors.initials: A
authors.lastname: Lobo
authors.forename: Tomás
authors.initials: T
authors.lastname: Palomo
mesh_terms: D001288:Attention; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology* / Q000523:psychology; D003245:Consensus Statements as Topic; D005163:Factor Analysis, Statistical; D006801:Humans; D007858:Learning; D008568:Memory; D015337:Multicenter Studies as Topic; D009315:National Institute of Mental Health (U.S.); D009483:Neuropsychological Tests; D011340:Problem Solving; D015203:Reproducibility of Results; D012565:Schizophrenic Psychology; D013030:Spain; D014175:Translating; D014481:United States