title: Effects of chalazion excision on ocular aberrations.
abstract: OBJECTIVE
  The goal of this study was to compare higher-order aberrations before and after upper lid chalazion excision.
  
  
  METHODS
  Fourteen eyes from 12 patients (8 females, mean age: 28.7 ± 2.7 years) with upper lid chalazion were enrolled in this prospective interventional case series. Chalazia were excised by standard transconjunctival vertical incision. Ocular aberrations were evaluated by aberrometry (ZyWave) before and 2 months after chalazion excision.
  
  
  RESULTS
  Root mean square of total higher-order aberrations decreased from 0.67 ± 0.12 to 0.43 ± 0.15 μm (P = 0.012) after excision. The root mean square of Zernike orders in the vertical and horizontal trefoil and horizontal coma were decreased after excision. Orbscan IIz tomography showed a statistically significant decrease in 5 mm zone irregularity (P = 0.027) and an increase in minimum simulated keratometry after surgery (P = 0.046).
  
  
  CONCLUSIONS
  Chalazion increases higher-order aberrations, as measured by the Hartmann-Shack aberrometer, which could affect the preoperative evaluation and results of refractive surgery, especially wavefront-guided approaches. Chalazion excision could reduce ocular aberrations and is recommended before refractive surgeries.
authors.affiliation: Eye Research Center, Khatam-al-Anbia Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Ali A
authors.initials: AA
authors.lastname: Sabermoghaddam
authors.forename: Siamak
authors.initials: S
authors.lastname: Zarei-Ghanavati
authors.forename: Mojtaba
authors.initials: M
authors.lastname: Abrishami
mesh_terms: D057128:Aberrometry; D000293:Adolescent; D000328:Adult; D017043:Chalazion / Q000503:physiopathology / Q000601:surgery*; D019781:Corneal Topography; D057108:Corneal Wavefront Aberration / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D013508:Ophthalmologic Surgical Procedures; D011446:Prospective Studies; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult