title: Itpr3 Is responsible for the mouse tufted (tf) locus.
abstract: The tf (tufted) locus is responsible for a classic phenotype of hair loss and regrowth in mice. It is a characteristic of the BTBR strain. Here, we use a combination of positional cloning methods and complementation mapping to identify Itpr3, the inositol triphosphate receptor type 3, as the gene responsible for the tf locus.
authors.affiliation: Monell Chemical Senses Center, 3500 Market St., Philadelphia, PA 19104, USA.
authors.forename: Hillary T
authors.initials: HT
authors.lastname: Ellis
authors.forename: Michael G
authors.initials: MG
authors.lastname: Tordoff
authors.forename: M Rockwell
authors.initials: MR
authors.lastname: Parker
mesh_terms: D000818:Animals; D005260:Female; D005838:Genotype; D053496:Inositol 1,4,5-Trisphosphate Receptors / Q000235:genetics*; D008297:Male; D051379:Mice; D010641:Phenotype; D040641:Quantitative Trait Loci
chemical_list: C582634:ITPR3 protein, mouse; D053496:Inositol 1,4,5-Trisphosphate Receptors