title: Artefact reduction in optoacoustic tomographic imaging by estimating the distribution of acoustic scatterers.
abstract: The quality of optoacoustic tomographic reconstructions can be severely affected by acoustic reflections or scattering arising at interfaces of highly mismatched organs, such as bones, lungs, or other air-containing cavities. We present a procedure to reduce the associated artefacts based on estimation of the acoustic scatterers distribution within the imaged object. Signals generated by a strong optical absorber are processed and used in a weighted back-projection algorithm. Experimental results in a tissue-mimicking phantom clearly demonstrate improved performance as compared to the case in which no information on the distribution of acoustic scatterers is available.
authors.affiliation: Technical University of Munich and Helmholtz Center Munich, Institute for Biological and Medical Imaging, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany.
authors.forename: X Luís
authors.initials: XL
authors.lastname: Deán-Ben
authors.forename: Vasilis
authors.initials: V
authors.lastname: Ntziachristos
authors.forename: Daniel
authors.initials: D
authors.lastname: Razansky
mesh_terms: D000465:Algorithms; D016477:Artifacts; D007091:Image Processing, Computer-Assisted / Q000379:methods / Q000706:statistics & numerical data; D055620:Optical Phenomena; D019047:Phantoms, Imaging; D061088:Photoacoustic Techniques / Q000379:methods* / Q000706:statistics & numerical data; D012542:Scattering, Radiation; D041622:Tomography, Optical / Q000379:methods* / Q000706:statistics & numerical data