title: Solvent-free synthesis, spectral correlations and antimicrobial activities of some aryl imines.
abstract: A series of aryl imines have been synthesized by Fly-ash: H2SO4 catalyzed microwave assisted process under solvent-free conditions. The yields of the imines have been found to be more than 87%. The purity of all imines has been checked using their physical constants and spectral data as published earlier in literature. The UV λmaxCN(nm), infrared νCN(cm(-1)), NMR δ(ppm) of CH and CN spectral data have been correlated with Hammett substituent constants and F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the above spectral data has been studied. The antimicrobial activities of All synthesised imines have been studied using Bauer-Kirby method.
authors.affiliation: PG & Research Department of Chemistry, Government Arts College, C-Mutlur, Chidambaram 608 102, India.
authors.forename: R
authors.initials: R
authors.lastname: Suresh
authors.forename: D
authors.initials: D
authors.lastname: Kamalakkannan
authors.forename: K
authors.initials: K
authors.lastname: Ranganathan
authors.forename: R
authors.initials: R
authors.lastname: Arulkumaran
authors.forename: R
authors.initials: R
authors.lastname: Sundararajan
authors.forename: S P
authors.initials: SP
authors.lastname: Sakthinathan
authors.forename: S
authors.initials: S
authors.lastname: Vijayakumar
authors.forename: K
authors.initials: K
authors.lastname: Sathiyamoorthi
authors.forename: V
authors.initials: V
authors.lastname: Mala
authors.forename: G
authors.initials: G
authors.lastname: Vanangamudi
authors.forename: K
authors.initials: K
authors.lastname: Thirumurthy
authors.forename: P
authors.initials: P
authors.lastname: Mayavel
authors.forename: G
authors.initials: G
authors.lastname: Thirunarayanan
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy; D005658:Fungi / Q000187:drug effects; D006801:Humans; D006841:Hydrocarbons, Aromatic / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D007097:Imines / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D009181:Mycoses / Q000188:drug therapy; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000890:Anti-Infective Agents; D006841:Hydrocarbons, Aromatic; D007097:Imines