title: A favourable response to surgical intervention and hyperbaric oxygen therapy in pyoderma gangrenosum.
abstract: Pyoderma gangrenosum (PG) is a neutrophilic dermatosis characterised with ulcerations. Inflammatory bowel diseases (ulcerative colitis and Crohn's disease) and haematologic diseases (leukaemia, preleukaemia and monoclonal gammopathy) have been reported in about 40-50% of PG patients in whom the treatment of the underlying disease is important for the improvement of the lesions. We herein report a colorectal adenocarcinoma patient with PG, who responded partially to topical treatments and systemic immunosuppressants and healed completely with the aid of surgical wound repair and hyperbaric oxygen therapy.
authors.affiliation: Department of Dermatology, Sisli Etfal Training and Research Hospital, Istanbul, Turkey.
authors.forename: Ilknur
authors.initials: I
authors.lastname: Altunay
authors.forename: Asli
authors.initials: A
authors.lastname: Kucukunal
authors.forename: Sezgi
authors.initials: S
authors.lastname: Sarikaya
authors.forename: Gulsen
authors.initials: G
authors.lastname: Tukenmez Demirci
mesh_terms: D001706:Biopsy; D062109:Dermatologic Surgical Procedures / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D017511:Pyoderma Gangrenosum / Q000175:diagnosis / Q000628:therapy*
keywords: Cyclosporine; Hyperbaric oxygen therapy; Leg ulcer; Prednisolone; Pyoderma gangrenosum