title: Detection of Clostridium perfringens type C in pig herds following disease outbreak and subsequent vaccination.
abstract: Immunisation of sows using Clostridium perfringens type C toxoid vaccines is recommended to prevent necrotising enteritis (NE) on pig breeding farms. Absence of disease, however, oftentimes leads to the false assumption of pathogens being eradicated. The prevalence of C perfringens type C was determined by PCR in faecal samples of piglets and sows in three Swiss pig breeding farms two to four years after implementation of a vaccination programme following disease outbreaks. C perfringens type C could still be detected several years after an outbreak despite absence of NE. In-herd prevalence of the pathogens varied significantly between the farms and was also lower compared with a farm which experienced a recent outbreak. In conclusion, C perfringens type C can be detected on once-affected farms, even in the absence of NE for several years.
authors.affiliation: Swine Clinic, Vetsuisse Faculty, University of Bern, Bern 3001, Switzerland.
authors.forename: K
authors.initials: K
authors.lastname: Schäfer
authors.forename: M
authors.initials: M
authors.lastname: Wyder
authors.forename: S
authors.initials: S
authors.lastname: Gobeli
authors.forename: A
authors.initials: A
authors.lastname: Candi
authors.forename: M G
authors.initials: MG
authors.lastname: Doherr
authors.forename: B
authors.initials: B
authors.lastname: Zehnder
authors.forename: W
authors.initials: W
authors.lastname: Zimmermann
authors.forename: H
authors.initials: H
authors.lastname: Posthaus
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001428:Bacterial Vaccines / Q000008:administration & dosage* / Q000276:immunology; D003015:Clostridium Infections / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary*; D003016:Clostridium perfringens / Q000302:isolation & purification*; D004196:Disease Outbreaks / Q000517:prevention & control / Q000662:veterinary*; D004751:Enteritis / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary; D004768:Enterotoxins / Q000235:genetics; D005243:Feces / Q000382:microbiology; D005260:Female; D008297:Male; D009336:Necrosis / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary; D015995:Prevalence; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control
chemical_list: D001428:Bacterial Vaccines; D004768:Enterotoxins