title: [Research advances on mechanisms of chemoresistance in acute myeloid leukemia].
abstract: Acute myeloid leukemia (AML) is a common type of hematopoietic malignancies seriously threatening human life. Resistance to chemotherapy is one of the main reasons for   recurrence and refractoriness of acute myeloid leukemia. The mechanisms of chemoresistance are complex. This article reviews the mechanisms of chemoresistance in acute myeloid   leukemia,the current research advances and the possible approach for reverse of drug resistance.
authors.affiliation: The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
authors.forename: Chun-mei
authors.initials: CM
authors.lastname: Yang
authors.forename: Wen-bin
authors.initials: WB
authors.lastname: Qian
mesh_terms: D019008:Drug Resistance, Neoplasm / Q000502:physiology*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy* / Q000503:physiopathology