title: Evaluation of serum adenosine deaminase and 5'-nucleotidase activities as probable markers in ovarian cancer.
abstract: Adenosine deaminase (ADA) and 5'-nucleotidase (5'-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5'-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.
authors.affiliation: Department of Biochemistry, Kasturba Medical College, 576 104 Manipal.
authors.forename: P
authors.initials: P
authors.lastname: Pragathi
authors.forename: P V
authors.initials: PV
authors.lastname: Bharath Kumar
authors.forename: P
authors.initials: P
authors.lastname: Amar Kumar
authors.forename: M
authors.initials: M
authors.lastname: Ramakanth Reddy
authors.forename: V
authors.initials: V
authors.lastname: Sravani
authors.forename: J
authors.initials: J
authors.lastname: Neeraja
authors.forename: Eapen
authors.initials: E
authors.lastname: Reeba Mary
authors.forename: K
authors.initials: K
authors.lastname: Gopalakrishna
keywords: 5′-NT; ADA; CA-125; Ovarian cancer