title: Aryllithiums with increasing steric crowding and lipophilicity prepared from chlorides in diethyl ether. The first directly prepared room-temperature-stable dilithioarenes.
abstract: A convenient procedure has been developed for the preparation of synthetically useful, room-temperature-stable aryllithiums starting from aryl chlorides and lithium metal. The method provides a route to aryllithiums which have previously not been accessible cleanly or could only be prepared by using more expensive starting materials.
authors.affiliation: Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, Athens 11635, Greece. kskretas@eie.gr
authors.forename: Constantinos G
authors.initials: CG
authors.lastname: Screttas
authors.forename: Barry R
authors.initials: BR
authors.lastname: Steele
authors.forename: Maria
authors.initials: M
authors.lastname: Micha-Screttas
authors.forename: Georgios A
authors.initials: GA
authors.lastname: Heropoulos
mesh_terms: D002384:Catalysis; D004986:Ether / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry*; D008055:Lipids / Q000737:chemistry; D008094:Lithium / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis*; D013696:Temperature
chemical_list: D006843:Hydrocarbons, Chlorinated; D008055:Lipids; D009942:Organometallic Compounds; D004986:Ether; D008094:Lithium