title: The birth of the Epitranscriptome: deciphering the function of RNA modifications.
abstract: Recent studies have found methyl-6-adenosine in thousands of mammalian genes, and this modification is most pronounced near the beginning of the 3' UTR. We present a perspective on current work and new single-molecule sequencing methods for detecting RNA base modifications.
authors.forename: Yogesh
authors.initials: Y
authors.lastname: Saletore
authors.forename: Kate
authors.initials: K
authors.lastname: Meyer
authors.forename: Jonas
authors.initials: J
authors.lastname: Korlach
authors.forename: Igor D
authors.initials: ID
authors.lastname: Vilfan
authors.forename: Samie
authors.initials: S
authors.lastname: Jaffrey
authors.forename: Christopher E
authors.initials: CE
authors.lastname: Mason
mesh_terms: D020413:3' Untranslated Regions; D000241:Adenosine / Q000378:metabolism*; D000818:Animals; D057890:Epigenomics / Q000379:methods*; D057809:HEK293 Cells; D056945:Hep G2 Cells; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods*; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL; D012313:RNA / Q000378:metabolism*; D012323:RNA Processing, Post-Transcriptional; D059467:Transcriptome
chemical_list: D020413:3' Untranslated Regions; D012313:RNA; D000241:Adenosine