title: [Biological activity of Penicillium sp. 10-51 exometabolites].
abstract: Silica gel column chromatography (silica gel "L" II kind of activity 100/160 mkm) of the chloroform extract from the cultural filtrate of Penicillium sp. 10-51 gave two fractions (chloroform and chloroform-acetone, 5:1) having biological activity. Recrystallization yielded two compounds. On the basis of physico-chemical and spectral data these compounds were identified as curvularin and hydroxycurvularin, which have a large spectrum of biological action as to bacteria, yeast, blue-green algae and phytopathogenic micromycetes.
authors.forename: Ia I
authors.initials: IaI
authors.lastname: Savchuk
authors.forename: A M
authors.initials: AM
authors.lastname: Zaĭchenko
authors.forename: E S
authors.initials: ES
authors.lastname: Tsyganenko
mesh_terms: D000096:Acetone / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D020171:Botrytis / Q000187:drug effects / Q000254:growth & development; D002725:Chloroform / Q000737:chemistry; D002850:Chromatography, Gel; D002855:Chromatography, Thin Layer; D003470:Culture Media; D000458:Cyanobacteria / Q000187:drug effects / Q000254:growth & development; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000254:growth & development; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000254:growth & development; D010407:Penicillium / Q000737:chemistry* / Q000378:metabolism; D058428:Silica Gel; D013057:Spectrum Analysis; D015025:Zearalenone / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D003470:Culture Media; D000096:Acetone; D015025:Zearalenone; D058428:Silica Gel; D002725:Chloroform; C013455:curvularin