title: Pore formation in lipid bilayer membranes made of phosphatidylcholine and cholesterol followed by means of constant current.
abstract: This paper describes the application of chronopotentiometry to lipid bilayer research. The experiments were performed on bilayer lipid membranes composed of phosphatidylcholine and cholesterol and formed using the painting technique. Chronopotentiometric (U = f(t)) measurements were used to determine the membrane capacitance, resistance, and breakdown voltage as well as pore conductance and diameter.
authors.affiliation: Institute of Chemistry, University of Bialystok, Al. J. Pilsudskiego 11/4, 15-443, Bialystok, Poland. monikan@uwb.edu.pl
authors.forename: Monika
authors.initials: M
authors.lastname: Naumowicz
authors.forename: Zbigniew Artur
authors.initials: ZA
authors.lastname: Figaszewski
mesh_terms: D002463:Cell Membrane Permeability; D002784:Cholesterol / Q000737:chemistry*; D025802:Electric Capacitance; D017097:Electric Impedance; D018274:Electroporation; D008051:Lipid Bilayers / Q000737:chemistry*; D010713:Phosphatidylcholines / Q000737:chemistry*; D016062:Porosity; D011199:Potentiometry / Q000379:methods
chemical_list: D008051:Lipid Bilayers; D010713:Phosphatidylcholines; D002784:Cholesterol