title: Group A streptococcal infections in obstetrics and gynecology.
abstract: Group A streptococcal (GAS) infections continue to be an infrequent, but potentially lethal infections in women despite the victory over childbed fever in the 1800s. Invasive group A streptococcal infection still causes 40% of septic deaths among patients with postpartum endometritis, necrotizing fasciitis, and toxic shock syndrome. Many times symptoms and signs of this infection are nonspecific, but laboratory evaluation can suggest serious infection. The prudent combination of antibiotic and surgical therapy can be lifesaving.
authors.affiliation: Department of Obstetrics and Gynecology, Medical University of South Carolina, Charleston, SC, USA.
authors.forename: Bassam H
authors.initials: BH
authors.lastname: Rimawi
authors.forename: David E
authors.initials: DE
authors.lastname: Soper
authors.forename: David A
authors.initials: DA
authors.lastname: Eschenbach
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D004716:Endometritis / Q000382:microbiology; D019115:Fasciitis, Necrotizing / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*; D011645:Puerperal Infection / Q000382:microbiology*; D012772:Shock, Septic / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D013290:Streptococcal Infections / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology* / Q000628:therapy; D013297:Streptococcus pyogenes / Q000378:metabolism / Q000472:pathogenicity; D013530:Surgical Wound Infection / Q000150:complications / Q000382:microbiology*; D014621:Vagina / Q000382:microbiology; D037521:Virulence Factors / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D037521:Virulence Factors