title: Blocking VWF platelet binding to treat TTP.
abstract: Two articles in this issue of Blood from Feys et al and Callewaert et al, respectively, have employed very similar and elegant strategies in attempts to ameliorate the symptoms of thrombotic thrombocytopenic purpura (TTP).
authors.affiliation: Imperial College London, UK.
authors.forename: Isabelle I
authors.initials: II
authors.lastname: Salles
authors.forename: James T B
authors.initials: JT
authors.lastname: Crawley
mesh_terms: D000743:Anemia, Hemolytic / Q000188:drug therapy*; D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D019038:Platelet Glycoprotein GPIb-IX Complex / Q000037:antagonists & inhibitors*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000188:drug therapy*; D014841:von Willebrand Factor / Q000037:antagonists & inhibitors*
chemical_list: D000911:Antibodies, Monoclonal; D005343:Fibrinolytic Agents; D019038:Platelet Glycoprotein GPIb-IX Complex; D014841:von Willebrand Factor