title: RNA interference: Systemic RNAi SIDes with endosomes.
abstract: Systemic RNAi, the intercellular spreading of RNAi silencing, requires SID-1 and SID-3 to import silencing signals in Caenorhabditis elegans. How are these signals exported? SID-5, an endosome-associated protein, is a candidate for the job.
authors.affiliation: Division of Endocrinology and Metabolism, Department of Medicine, McGill University and the Research Institute of the McGill University Health Centre, Montreal, Quebec H3A 0C7, Canada. christian.rocheleau@mcgill.ca
authors.forename: Christian E
authors.initials: CE
authors.lastname: Rocheleau
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics* / Q000378:metabolism*; D029742:Caenorhabditis elegans Proteins / Q000378:metabolism*; D008562:Membrane Glycoproteins / Q000378:metabolism*; D034622:RNA Interference; D020691:rab GTP-Binding Proteins / Q000378:metabolism*; D000090802:rab7 GTP-Binding Proteins
chemical_list: D029742:Caenorhabditis elegans Proteins; C413182:LMP-1 protein, C elegans; D008562:Membrane Glycoproteins; D000090802:rab7 GTP-Binding Proteins; D020691:rab GTP-Binding Proteins