title: Bacterial metabolism of polycyclic aromatic hydrocarbons: strategies for bioremediation.
abstract: Polycyclic aromatic hydrocarbons (PAHs) are compounds of intense public concern due to their persistence in the environment and potentially deleterious effects on human, environmental and ecological health. The clean up of such contaminants using invasive technologies has proven to be expensive and more importantly often damaging to the natural resource properties of the soil, sediment or aquifer. Bioremediation, which exploits the metabolic potential of microbes for the clean-up of recalcitrant xenobiotic compounds, has come up as a promising alternative. Several approaches such as improvement in PAH solubilization and entry into the cell, pathway and enzyme engineering and control of enzyme expression etc. are in development but far from complete. Successful application of the microorganisms for the bioremediation of PAH-contaminated sites therefore requires a deeper understanding of the physiology, biochemistry and molecular genetics of potential catabolic pathways. In this review, we briefly summarize important strategies adopted for PAH bioremediation and discuss the potential for their improvement.
authors.affiliation: Institute of Microbial Technology, Sector-39A, Chandigarh, India.
authors.forename: Archana
authors.initials: A
authors.lastname: Chauhan
authors.lastname: Fazlurrahman
authors.forename: John G
authors.initials: JG
authors.lastname: Oakeshott
authors.forename: Rakesh K
authors.initials: RK
authors.lastname: Jain
keywords: Bioavailability; Bioremediation; Chemotaxis; Genetic engineering; Polycyclic aromatic hydrocarbons; Surfactants