title: Osteoclast-like Giant Cell Tumor of Parotid Gland with a Carcinomatous Component: A Case Report.
abstract: The giant cell tumor of the salivary gland is very rare, and 20 cases have been reported in the English-language literature. We report an additional case. A 57-year old man had noticed a mass in the right parotid area for several weeks. The diagnosis using aspiration cytology was a giant cell tumor possibly with a carcinomatous component. Superficial parotidectomy was carried out. The resected parotid gland contained a 1.8 cm-sized well-circumscribed brownish tumor. Histologically the tumor consisted of evenly distributed osteoclast-like giant cells, mononuclear cells and two small foci of a carcinomatous component. The osteoclast-like giant cells and mononuclear cells were positive for vimentin and CD68, and the carcinomatous component was positive for cytokeratin and epithelial membrane antigen. There was no metastatic lesion in the cervical lymph nodes. We believe this is the first case in Korea of an osteoclast-like giant cell tumor of the parotid gland.
authors.affiliation: Department of Pathology, Gyeongsang National University School of Medicine, Jinju, Korea.
authors.forename: Jung Wook
authors.initials: JW
authors.lastname: Yang
authors.forename: Hyeon Cheol
authors.initials: HC
authors.lastname: Kim
authors.forename: Jeong Hee
authors.initials: JH
authors.lastname: Lee
authors.forename: Jong Sil
authors.initials: JS
authors.lastname: Lee
authors.forename: Dong Chul
authors.initials: DC
authors.lastname: Kim
authors.forename: Dae Hyun
authors.initials: DH
authors.lastname: Song
authors.forename: Jin Pyeong
authors.initials: JP
authors.lastname: Kim
authors.forename: Gyung Hyuck
authors.initials: GH
authors.lastname: Ko
keywords: Giant cell tumors; Salivary glands