title: [The development of secondary immunodeficiency in body when exposed to the effect of xenobiotics with immunosuppressive activity].
abstract: The State Education Institution of Higher professional education "The Orenburg State Medical Academy of Federal Agency in Public Health and Social Development". In the experiment on mice (CBA x C57Bl6) F1 and Wistar rats is shown the protective effect of triterpenoid plant--miliatsina (3-beta-methoxy-delta18-oleanena) in relation to the humoral immune response and clearance macrophage function hepatic xenobiotic conditions of use--methotrexate. The results define the term as used miliatsina immunoprotector with adverse effects on the body of environmental and industrial chemical factors that form the secondary immunodeficiency.
authors.forename: O V
authors.initials: OV
authors.lastname: Kalinina
authors.forename: A D
authors.initials: AD
authors.lastname: Zheleznova
authors.forename: T V
authors.initials: TV
authors.lastname: Panfilova
authors.forename: B A
authors.initials: BA
authors.lastname: Frolov
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000139:chemically induced* / Q000276:immunology; D008264:Macrophages / Q000187:drug effects* / Q000276:immunology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D010587:Phagocytosis / Q000187:drug effects; D051381:Rats; D017208:Rats, Wistar; D015262:Xenobiotics / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D015262:Xenobiotics