title: The use of dermabond® as an adjunct to wound closure after total knee arthroplasty: examining immediate post-operative wound drainage.
abstract: Wound drainage after total knee arthroplasty (TKA) can be detrimental to surgical outcome. This IRB-approved randomized, prospective, blinded study examined the use of Dermabond® as an adjunct to wound closure after TKA. We proposed that Dermabond® supplementation to wound closure would result in a significant decrease in wound drainage after TKA. After standardized closure, patients were randomized into experimental or control groups with the experimental group receiving Dermabond® supplementation. Standardized dressings were evaluated postoperatively and drainage units were compared using a Mann-Whitney U Test. The median drainage for the Dermabond group (153) was lower than the drainage for the control group (657) at a statistically significant level (P<0.001).
authors.affiliation: Albert Einstein College of Medicine/Montefiore Medical Center, 1250 Waters Place, Bronx, NY 10461, USA.
authors.forename: Yaser
authors.initials: Y
authors.lastname: El-Gazzar
authors.forename: Daniel C
authors.initials: DC
authors.lastname: Smith
authors.forename: Sun Jin
authors.initials: SJ
authors.lastname: Kim
authors.forename: David M
authors.initials: DM
authors.lastname: Hirsh
authors.forename: Yossef
authors.initials: Y
authors.lastname: Blum
authors.forename: Marcie
authors.initials: M
authors.lastname: Cobelli
authors.forename: Hillel W
authors.initials: HW
authors.lastname: Cohen
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D003487:Cyanoacrylates; D004322:Drainage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D011446:Prospective Studies; D016037:Single-Blind Method; D013997:Time Factors; D014014:Tissue Adhesives; D058106:Wound Closure Techniques; D014945:Wound Healing
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives; C100832:octyl 2-cyanoacrylate