title: Bilateral metastatic melanoma to the extraocular-muscles simulating thyroid eye disease.
abstract: We report a case of bilateral metastatic melanoma to the extraocular muscles that simulated thyroid eye disease. A 71-year-old man presented with bilateral painless axial proptosis, lid retraction and left gaze restriction. Orbital CT scan demonstrated enlargement of the extraocular muscles with tendon sparing, consistent with thyroid eye disease. However, thyroid function tests and antithyroid antibodies were normal. Systemic review including orbital MRI scan determined the correct diagnosis of metastatic melanoma to the orbit. Metastatic melanoma to the orbit can simulate thyroid eye disease.
authors.affiliation: Hospital de Egas Moniz-Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal.
authors.forename: Ana Catarina
authors.initials: AC
authors.lastname: Almeida
authors.forename: Adrian
authors.initials: A
authors.lastname: Fung
authors.forename: Marta Esteves
authors.initials: ME
authors.lastname: Guedes
authors.forename: João Marques
authors.initials: JM
authors.lastname: Costa
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D049970:Graves Ophthalmopathy / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary; D019042:Muscle Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000556:secondary; D009801:Oculomotor Muscles / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*