title: Circadian rhythms: An electric jolt to the clock.
abstract: The animal circadian pacemaker is composed of two transcriptional feedback loops, which regulate electrical activity in circadian neurons. Surprisingly, a new study reports that electrical activity can reprogram circadian transcription, and identifies CREB proteins as candidates for this reprograming.
authors.affiliation: Department of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Patrick.Emery@umassmed.edu
authors.forename: Patrick
authors.initials: P
authors.lastname: Emery
mesh_terms: D051698:Activating Transcription Factor 2 / Q000502:physiology*; D000818:Animals; D057906:Circadian Clocks / Q000502:physiology*; D002940:Circadian Rhythm; D004330:Drosophila / Q000502:physiology*; D029721:Drosophila Proteins / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D059467:Transcriptome
chemical_list: C519913:ATF-2 protein, Drosophila; D051698:Activating Transcription Factor 2; D029721:Drosophila Proteins