title: Antibodies against free radical modified DNA in cancer patients.
abstract: In this study we have modified DNA by exposing it to ultraviolet light in the presence of hydrogen peroxide. The modified DNA was probed for binding to the antibodies present in the sera of patients suffering from various types of cancer. Higher recognition of modified DNA, as compared to native DNA, by antibodies from cancer patients has got far reaching significance.
authors.affiliation: Department of Biochemistry, Aligarh Muslim University, 202 002 Aligarh.
authors.forename: A D
authors.initials: AD
authors.lastname: Deepak
authors.lastname: Moinuddin
authors.forename: S A
authors.initials: SA
authors.lastname: Siddiqui
authors.forename: A
authors.initials: A
authors.lastname: Ali
keywords: Cancer; DNA damage; Reactive oxygen species