title: The effect of percutaneous coronary intervention in patients suffering from ST-segment elevation myocardial infarction complicated by out-of-hospital cardiac arrest on 30 days survival.
abstract: OBJECTIVE
  To question the beneficial effects of the recommended early percutaneous coronary intervention (PCI) after out-of-hospital cardiac arrest on 30-day survival with favourable neurological outcome.
  
  
  METHODS
  Prospectively collected data of 1277 out of hospital cardiac arrest patients between 2005 and 2010 from a registry at a tertiary care university hospital were used for a cohort study.
  
  
  RESULTS
  In 494 (39%) arrest patients ST-segment elevation was identified in 249 (19%). Within 12h after restoration of spontaneous circulation catheter laboratory investigations were initiated in 197 (79%) and PCI in 183 (93%) (78% got PCI in less than 180 min). Adjustment for a cumulative time without chest compressions <2 min, initial shockable rhythm, cardiac arrest witnessed by healthcare professionals, and a higher core temperature at time of hospitalization reduced the effect of PCI on favourable neurological outcome at 30 days (OR 1.40; 95% CI, 0.53-3.7) compared to the univariate analysis (OR 2.52; 95% CI, 1.42-4.48).
  
  
  CONCLUSIONS
  This cohort study failed to demonstrate the beneficial effects of PCI as part of post-resuscitation care on 30-day survival with a favourable neurological outcome.
authors.affiliation: Department of Emergency Medicine, Medical University of Vienna, Austria.
authors.forename: Christoph
authors.initials: C
authors.lastname: Weiser
authors.forename: Christoph
authors.initials: C
authors.lastname: Testori
authors.forename: Fritz
authors.initials: F
authors.lastname: Sterz
authors.forename: Andreas
authors.initials: A
authors.lastname: Schober
authors.forename: Mathias
authors.initials: M
authors.lastname: Stöckl
authors.forename: Peter
authors.initials: P
authors.lastname: Stratil
authors.forename: Christian
authors.initials: C
authors.lastname: Wallmüller
authors.forename: David
authors.initials: D
authors.lastname: Hörburger
authors.forename: Alexander
authors.initials: A
authors.lastname: Spiel
authors.forename: Istepan
authors.initials: I
authors.lastname: Kürkciyan
authors.forename: Clemens
authors.initials: C
authors.lastname: Gangl
authors.forename: Harald
authors.initials: H
authors.lastname: Herkner
authors.forename: Michael
authors.initials: M
authors.lastname: Holzer
mesh_terms: D000368:Aged; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000401:mortality / Q000628:therapy*; D058687:Out-of-Hospital Cardiac Arrest / Q000401:mortality / Q000628:therapy*; D062645:Percutaneous Coronary Intervention / Q000379:methods* / Q000401:mortality; D011446:Prospective Studies; D015996:Survival Rate; D016896:Treatment Outcome