title: [Isolated splenic peliosis: a case report].
abstract: Peliosis is a rare vascular lesion that is usually found in the liver, and less frequently in other hematolymphoid organs. We report a case of isolated splenic peliosis discovered in a 65-year-old man with an erysipelas and a thrombocytopenia. The computed tomography abdominal scan revealed an heterogen multinodular splenic mass. Splenectomy was performed and platelet counts returned to normal levels. The histopathologic examination revealed dilations of sinuses in the red pulp. The endothelial cells lining cavities stain for CD8 and CD31 but not for CD34. Splenic peliosis is a rare benign disease of unknown aetiology, which belongs to the group of vascular neoplasms of the spleen. The final diagnosis is based on the pathology examen. We review the histologic and immunohistochemical arguments of this diagnostic and expose the differential diagnoses.
authors.affiliation: Service de pathologie, hôpital Émile-Muller, rue du Docteur-Laennec, 68070 Mulhouse, France. carenard@free.fr
authors.forename: Caroline
authors.initials: C
authors.lastname: Renard
authors.forename: Daciana
authors.initials: D
authors.lastname: Baumann
authors.forename: Sébastien
authors.initials: S
authors.lastname: Thiriat
authors.forename: Agathe
authors.initials: A
authors.lastname: Debliquis
authors.forename: Véronique
authors.initials: V
authors.lastname: Lindner
authors.forename: Sylvie
authors.initials: S
authors.lastname: Thiébault
mesh_terms: D000368:Aged; D000740:Anemia / Q000209:etiology; D016512:Ankle Injuries / Q000150:complications; D000943:Antigens, Differentiation / Q000032:analysis; D016827:CD8 Antigens / Q000032:analysis; D003951:Diagnostic Errors; D042783:Endothelial Cells / Q000737:chemistry; D004886:Erysipelas / Q000209:etiology; D005494:Folic Acid Deficiency / Q000097:blood / Q000150:complications; D006801:Humans; D008297:Male; D009529:Nicardipine / Q000009:adverse effects; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000032:analysis; D013154:Spleen / Q000098:blood supply; D013156:Splenectomy; D013158:Splenic Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D013921:Thrombocytopenia / Q000209:etiology; D014057:Tomography, X-Ray Computed; D014652:Vascular Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery
chemical_list: D000943:Antigens, Differentiation; D016827:CD8 Antigens; D019408:Platelet Endothelial Cell Adhesion Molecule-1; D009529:Nicardipine