title: Combined involvement of muscle, nerve, and myoneural junction following leptospira infection.
abstract: Leptospirosis is a zoonosis prevalent worldwide and is endemic in many parts of India. In early leptospiremic as well as late immune phase of the disease kidney, liver, heart, and lungs are commonly involved. Neurological manifestations are rare but may occur during immune phase in the form of aseptic meningitis, meningoencephalitis, seizures, myelitis, polyradiculoneuritis, and myalgia. In this report, we describe a rare case of leptospirosis with combined involvement of nerve, muscle, and myoneural junction in generalized fashion along with pulmonary, renal, and hepatic dysfunction.
authors.affiliation: Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India. drspradhan@rediffmail.com
authors.forename: Sunil
authors.initials: S
authors.lastname: Pradhan
authors.forename: Ruchika
authors.initials: R
authors.lastname: Tandon
authors.forename: Janak
authors.initials: J
authors.lastname: Kishore
mesh_terms: D000328:Adult; D004576:Electromyography; D005155:Facial Nerve Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D007922:Leptospirosis / Q000150:complications* / Q000473:pathology*; D017093:Liver Failure / Q000209:etiology; D018482:Muscle, Skeletal / Q000503:physiopathology*; D009469:Neuromuscular Junction / Q000503:physiopathology*; D051437:Renal Insufficiency / Q000209:etiology