title: Effect of early diabetes on the expression of alpha-1 adrenergic receptors in aorta and carotid arteries of Wistar Kyoto and spontaneously hypertensive rats.
abstract: Hypertension and diabetes have been related to noradrenergic system impairment, especially to the response mediated by alpha-1 receptors. The aim of this work was to investigate possible changes in the expression of alpha-1 adrenergic receptors in aorta and carotid arteries of Wistar Kyoto and spontaneously hypertensive rats after 4 weeks of the onset of diabetes. Our results suggest that early diabetes modifies the expression of alpha-1 adrenergic receptors in aorta and carotid arteries of both WKY and SHR strains in a different way.
authors.affiliation: Seccion de Posgrado, Instituto Politecnico Nacional , Mexico.
authors.forename: Jessica
authors.initials: J
authors.lastname: Edith-Rodriguez
authors.forename: Aldo Arturo
authors.initials: AA
authors.lastname: Resendiz-Albor
authors.forename: Ivonne Maciel
authors.initials: IM
authors.lastname: Arciniega-Martinez
authors.forename: Rafael
authors.initials: R
authors.lastname: Campos-Rodriguez
authors.forename: Enrique
authors.initials: E
authors.lastname: Hong
authors.forename: Fengyang
authors.initials: F
authors.lastname: Huang
authors.forename: Santiago
authors.initials: S
authors.lastname: Villafaña
mesh_terms: D000818:Animals; D001011:Aorta / Q000378:metabolism; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure; D002339:Carotid Arteries / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism* / Q000503:physiopathology; D003925:Diabetic Angiopathies / Q000378:metabolism* / Q000503:physiopathology; D006973:Hypertension / Q000378:metabolism* / Q000503:physiopathology; D008297:Male; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D018340:Receptors, Adrenergic, alpha-1 / Q000145:classification / Q000378:metabolism*
chemical_list: D001786:Blood Glucose; D018340:Receptors, Adrenergic, alpha-1