title: An amplified chemiluminescence aptasensor based on bi-resonance energy transfer on gold nanoparticles and exonuclease III-catalyzed target recycling.
abstract: We have developed an amplified chemiluminescence aptasensor based on bi-resonance energy transfer on gold nanoparticles and exonuclease III-catalyzed target recycling. This assay exhibits high detection sensitivity over traditional biosensors in three orders of magnitude and high specificity for target molecules.
authors.affiliation: Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education), College of Chemistry and Chemical Engineering, Guangxi Normal University, Guilin 541004, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
authors.forename: Shulin
authors.initials: S
authors.lastname: Zhao
authors.forename: Zhen-Feng
authors.initials: ZF
authors.lastname: Chen
authors.forename: Ming
authors.initials: M
authors.lastname: Shi
authors.forename: Jia
authors.initials: J
authors.lastname: Chen
authors.forename: Hong
authors.initials: H
authors.lastname: Liang
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry / Q000378:metabolism*; D055162:Biocatalysis; D015374:Biosensing Techniques; D004735:Energy Transfer; D005090:Exodeoxyribonucleases / Q000737:chemistry / Q000378:metabolism*; D006046:Gold / Q000737:chemistry / Q000378:metabolism*; D008163:Luminescent Measurements; D053768:Metal Nanoparticles / Q000737:chemistry*
chemical_list: D052157:Aptamers, Nucleotide; D006046:Gold; D005090:Exodeoxyribonucleases; C020133:exodeoxyribonuclease III