title: Long genomic DNA amplicons adsorption onto unmodified gold nanoparticles for colorimetric detection of Bacillus anthracis.
abstract: Unmodified gold nanoparticles (GNPs) can be wrapped with long genomic single- and double-stranded DNA (ssDNA and dsDNA) molecules produced by asymmetric polymerase chain reaction (As-PCR). More importantly, the DNA-Au interaction can be utilized for colorimetric detection of a specific nucleic acid sequence in clinical samples.
authors.affiliation: CAS Key Laboratory for Biological Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology, 11 Beiyijie, Zhongguancun, Beijing 100190, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Deng
authors.forename: Xu
authors.initials: X
authors.lastname: Zhang
authors.forename: Anil
authors.initials: A
authors.lastname: Kumar
authors.forename: Guozang
authors.initials: G
authors.lastname: Zou
authors.forename: Xiaoning
authors.initials: X
authors.lastname: Zhang
authors.forename: Xing-Jie
authors.initials: XJ
authors.lastname: Liang
mesh_terms: D000327:Adsorption; D001408:Bacillus anthracis / Q000235:genetics*; D003124:Colorimetry; D004247:DNA / Q000737:chemistry; D004269:DNA, Bacterial / Q000032:analysis*; D004277:DNA, Single-Stranded / Q000737:chemistry; D016680:Genome, Bacterial; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*
chemical_list: D004269:DNA, Bacterial; D004277:DNA, Single-Stranded; D006046:Gold; D004247:DNA