title: Rethinking vector immunology: the role of environmental temperature in shaping resistance.
abstract: Recent ecological research has revealed that environmental factors can strongly affect insect immunity and influence the outcome of host-parasite interactions. To date, however, most studies examining immune function in mosquitoes have ignored environmental variability. We argue that one such environmental variable, temperature, influences both vector immunity and the parasite itself. As temperatures in the field can vary greatly from the ambient temperature in the laboratory, it will be essential to take temperature into account when studying vector immunology.
authors.affiliation: Merkle Laboratory, Center for Infectious Disease Dynamics, Department of Entomology, Pennsylvania State University, Orchard Road, University Park, State College, Pennsylvania 16802, USA. ccm15@psu.edu
authors.forename: Courtney C
authors.initials: CC
authors.lastname: Murdock
authors.forename: Krijn P
authors.initials: KP
authors.lastname: Paaijmans
authors.forename: Diana
authors.initials: D
authors.lastname: Cox-Foster
authors.forename: Andrew F
authors.initials: AF
authors.lastname: Read
authors.forename: Matthew B
authors.initials: MB
authors.lastname: Thomas
mesh_terms: D000818:Animals; D009033:Culicidae / Q000276:immunology* / Q000469:parasitology*; D004777:Environment; D006790:Host-Parasite Interactions / Q000276:immunology*; D006801:Humans; D007303:Insect Vectors / Q000276:immunology* / Q000469:parasitology*; D013696:Temperature