title: Spiritual well-being and quality of life in Iranian women with breast cancer undergoing radiation therapy.
abstract: OBJECTIVE
  Psychological distress and morbidity are common consequences of diagnosis and treatment of breast cancer and associated with poor quality of life (QOL). Spiritual well-being is an important aspect of QOL, but little is known about the spiritual well-being and its relationship with QOL in patients of different cultures such as Iranian Muslim patients. The aim of this study was to investigate the association of QOL and spirituality among patients with breast cancer undergoing radiation therapy.
  
  
  METHODS
  This was a cross-sectional study which was conducted in the Breast Cancer Research Center of St. S. Al-Shohada Hospital, Isfahan, Iran. Spiritual well-being was measured using the Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being Scale (FACIT-Sp12). The European Organisation for Research and Treatment of Cancer Quality of Life (EORTC QLQ-C30) and its supplementary breast cancer questionnaire (QLQ-BR23) were used to assess the quality of life of patients. Descriptive analysis, Pearson's correlation, and multiple regression analysis were performed for statistical assessment.
  
  
  RESULTS
  In all, 68 patients fulfilled the study's inclusion criteria and were interviewed. The mean global QOL was 41.42 (SD = 18.02), and the mean spiritual well-being was 28.41 (SD = 6.95). There was a significant positive correlation between general QOL and total spiritual well-being scores. Also, spiritual well-being, social functioning, pain, and arm symptoms were significant predictors of global QOL.
  
  
  CONCLUSIONS
  The results of this study provide evidence that breast cancer survivors in Iran experience a poor quality of life across a broad spectrum of health domains, particularly social, emotional, and spiritual, indicating that psychosocial-spiritual support should be considered in caring for patients with breast cancer.
authors.affiliation: Community Medicine Department, School of Medicine, Isfahan University of Medical Sciences, Hezar Jerib St., Isfahan, Iran.
authors.forename: Najmeh
authors.initials: N
authors.lastname: Jafari
authors.forename: Ziba
authors.initials: Z
authors.lastname: Farajzadegan
authors.forename: Ahmadreza
authors.initials: A
authors.lastname: Zamani
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Bahrami
authors.forename: Hamid
authors.initials: H
authors.lastname: Emami
authors.forename: Amir
authors.initials: A
authors.lastname: Loghmani
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000523:psychology* / Q000532:radiotherapy; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007492:Iran; D007514:Islam; D008875:Middle Aged; D010146:Pain / Q000453:epidemiology* / Q000209:etiology; D011788:Quality of Life; D012044:Regression Analysis; D029181:Spirituality; D011795:Surveys and Questionnaires; D055815:Young Adult