title: Course and outcome of renal transplant recipients admitted to the intensive care unit: a 20-year study.
abstract: BACKGROUND
  Renal transplantation represents the main treatment for end-stage renal disease. The goal of this study was to evaluate the course and outcome of renal transplant recipients admitted to the intensive care unit (ICU) and to analyze factors determining prognosis and mortality.
  
  
  METHODS
  The demographic features, data admission characteristics, and ICU courses of all renal transplant recipients admitted to our ICU from 1992 to 2012 were evaluated to analyze factors for mortality.
  
  
  RESULTS
  Eleven women and 50 men of mean age 45.5 ± 12.5 years were included in the study. Acute Physiology And Chronic Health Evaluation (APACHE II) and Sequential Organ Failure Assessment (SOFA) scores on ICU admission were 20 ± 5.7 and 8.5 ± 3.5, respectively. The main reasons for admission were as follows: sepsis (n = 27) or immediate postoperative complications (n = 16). Thirty-five patients during their ICU stay required hemodialysis and 34 needed catecholamines. The mortality rate was 42.6%. APACHE II Score, dialysis requirement, and sepsis as a reason for ICU admission were independently related to the mortality.
  
  
  CONCLUSIONS
  The mortality rate was higher than that of the general ICU population (42.6% vs 30%). The main reason for ICU admission of renal transplant recipients was sepsis.
authors.affiliation: Intensive Care Unit, "Hippokratio" University Hospital, Thessaloniki, Greece. elmoulou@yahoo.gr
authors.forename: E
authors.initials: E
authors.lastname: Mouloudi
authors.forename: E
authors.initials: E
authors.lastname: Massa
authors.forename: E
authors.initials: E
authors.lastname: Georgiadou
authors.forename: E
authors.initials: E
authors.lastname: Iosifidis
authors.forename: C
authors.initials: C
authors.lastname: Kydona
authors.forename: K
authors.initials: K
authors.lastname: Sgourou
authors.forename: E
authors.initials: E
authors.lastname: Anagnostara
authors.forename: G
authors.initials: G
authors.lastname: Imvrios
authors.forename: I
authors.initials: I
authors.lastname: Fouzas
authors.forename: V
authors.initials: V
authors.lastname: Papanikolaou
authors.forename: N
authors.initials: N
authors.lastname: Gritsi-Gerogianni
mesh_terms: D018806:APACHE; D000328:Adult; D002395:Catecholamines / Q000627:therapeutic use; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D007362:Intensive Care Units; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000401:mortality; D007902:Length of Stay; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D063305:Organ Dysfunction Scores; D010343:Patient Admission; D011183:Postoperative Complications / Q000175:diagnosis / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D011446:Prospective Studies; D006435:Renal Dialysis; D012121:Respiration, Artificial; D012189:Retrospective Studies; D012307:Risk Factors; D018805:Sepsis / Q000209:etiology / Q000628:therapy; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D002395:Catecholamines