title: Clinical outcomes of vertebroplasty or kyphoplasty for patients with vertebral compression fractures: a nationwide cohort study.
abstract: OBJECTIVE
  To evaluate the outcome of vertebroplasty or kyphoplasty (VK), in comparison with non-VK treatment, among patients hospitalized for first-ever vertebral compression fractures (VCFs).
  
  
  METHODS
  A population-based retrospective cohort study.
  
  
  METHODS
  Taiwan' s National Health Insurance claims data.
  
  
  METHODS
  All individuals aged ≥ 60 years who were newly discharged after hospitalization for a primary VCF diagnosis.
  
  
  METHODS
  Percutaneous vertebroplasty or kyphoplasty.
  
  
  METHODS
  Study outcomes were discharge outcome (re-hospitalization within 1 week, 1 month or 6 months, categorized by diagnosis) and the prescription of anti-osteoporosis medication for secondary fracture prevention. Potential selection bias was adjusted by using propensity score matching to select one conservatively treated patient (e.g. lumbar brace, analgesics, or physical therapy) matched to one patient receiving VK.
  
  
  RESULTS
  The study cohort consisted of 9238 patients who had been discharged after hospitalization for a first-ever VCF between 2004 and 2007. During the index hospitalization, 1018 patients received VK, compared with 8,220 patients who did not receive VK. Patients receiving percutaneous procedure group had a consistently lower incidence of 7-day re-hospitalization for any of the three outcomes (OR = 0.48; 95% CI: 0.32-0.72). Considering the cause of re-hospitalization separately, the vertebroplasty/kyphoplasty group had a significantly lower risk of 7-day re-hospitalization for fracture-related diagnosis (OR = 0.28, 95% CI: 0.12-0.68) and musculoskeletal diagnosis (OR = 0.08, 95% CI: 0.01-0.88) as well as a significantly lower risk of 1-month re-hospitalization (OR = 0.74; 95% CI: 0.59-0.93).
  
  
  CONCLUSIONS
  VK may protect patients with VCFs from short-term re-hospitalization and a greater need exists for anti-osteoporosis medication as secondary prevention for this at-risk patient group.
authors.affiliation: Institute of Health Welfare and Policy, National Yang Ming University, Taipei, Taiwan.
authors.forename: Yi-Wen
authors.initials: YW
authors.lastname: Tsai
authors.forename: Fei-Yuan
authors.initials: FY
authors.lastname: Hsiao
authors.forename: Yu-Wen
authors.initials: YW
authors.lastname: Wen
authors.forename: Yu-Hsiang
authors.initials: YH
authors.lastname: Kao
authors.forename: Li-Chuan
authors.initials: LC
authors.lastname: Chang
authors.forename: Weng-Foung
authors.initials: WF
authors.lastname: Huang
authors.forename: Li-Ning
authors.initials: LN
authors.lastname: Peng
authors.forename: Chien-Liang
authors.initials: CL
authors.lastname: Liu
authors.forename: Liang-Kung
authors.initials: LK
authors.lastname: Chen
mesh_terms: D000368:Aged; D005260:Female; D050815:Fractures, Compression / Q000601:surgery*; D006801:Humans; D058498:Kyphoplasty; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016103:Spinal Fractures / Q000601:surgery*; D013624:Taiwan; D016896:Treatment Outcome; D054854:Vertebroplasty