title: Core promoter-selective coregulators of transcription by RNA polymerase II.
abstract: The core promoter of eukaryotic genes is structurally and functionally diverse and contributes to the combinatorial control of gene-specific transcription. Recent findings identifying specific coactivators and architectural proteins as core promoter-specific basal cofactors for RNA polymerase II suggest possible mechanisms for the core promoter selectivity of certain regulators and enhancers.
authors.affiliation: Department of Biochemistry, University of California at Riverside, Riverside, CA, USA. ernest.martinez@ucr.edu
authors.forename: Ernest
authors.initials: E
authors.lastname: Martinez
mesh_terms: D000818:Animals; D006801:Humans; D011401:Promoter Regions, Genetic; D012319:RNA Polymerase II / Q000235:genetics*; D035165:Transcription Factors, General / Q000235:genetics
chemical_list: D035165:Transcription Factors, General; D012319:RNA Polymerase II
keywords: HMG proteins; Mediator; RNA polymerase II; TFIID; coactivators; core promoter-selective transcription; general transcription factors; positive and negative transcription cofactors