title: Constructing a quantitative correlation between N-substituent sizes of chiral ligands and enantioselectivities in asymmetric addition reactions of diethylzinc with benzaldehyde.
abstract: Using the asymmetric addition reaction of diethylzinc with benzylaldehyde as a model, we have demonstrated that excellent correlations exist between steric reference parameters (Charton and Sterimol values) for appropriate sets of substituents present on chiral 1,2-amino-phosphoramide ligands and the enantiomeric ratios of alcohol products produced in this process.
authors.affiliation: The State Key Lab of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.
authors.forename: Huayin
authors.initials: H
authors.lastname: Huang
authors.forename: Hua
authors.initials: H
authors.lastname: Zong
authors.forename: Guangling
authors.initials: G
authors.lastname: Bian
authors.forename: Ling
authors.initials: L
authors.lastname: Song