title: Nickel-catalyzed C-P cross-coupling of diphenylphosphine oxide with aryl chlorides.
abstract: A novel protocol for the preparation of various diarylphosphine oxide compounds via a Ni-catalyzed cross-coupling of aryl chlorides with R(2)P(O)H has been developed. Notably, this process exhibits the following very attractive features: (i) the process is simpler and operates under mild reaction conditions; (ii) the process is generally cheaper in part because the more accessible aryl chloride is used to form the C-P bond; (iii) the process avoids the need for simultaneous preparation and use of Ar(2)P(O)M.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China.
authors.forename: Hong-Yu
authors.initials: HY
authors.lastname: Zhang
authors.forename: Meng
authors.initials: M
authors.lastname: Sun
authors.forename: Yan-Na
authors.initials: YN
authors.lastname: Ma
authors.forename: Qiu-Ping
authors.initials: QP
authors.lastname: Tian
authors.forename: Shang-Dong
authors.initials: SD
authors.lastname: Yang
mesh_terms: D002384:Catalysis; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry*; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D010087:Oxides / Q000138:chemical synthesis* / Q000737:chemistry; D010720:Phosphines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D006571:Heterocyclic Compounds; D006843:Hydrocarbons, Chlorinated; D010087:Oxides; D010720:Phosphines; D009532:Nickel