title: Management of growing vestibular schwannomas.
abstract: Conservative management of small vestibular schwannomas is frequently proposed as most tumours do not grow. Anyway, tumour growth is reported in 30-40 % of the cases, so that surgery is consequently generally proposed. We primarily observed 161 patients affected by unilateral vestibular schwannomas. All patients were examined by means of gadolinium-enhanced magnetic resonance imaging scans. Tumour growth was recorded in 58 cases (35.8 %) and these subjects set up the group of study. Twenty-two (37.9 %) patients were surgically treated; tumour was always completely removed, all patients had normal facial function after surgery and only one patient suffered from a major complication (cerebellar haematoma). Fourteen patients (24.1 %) were submitted to radiotherapy, while one patient was lost at follow-up and another one died because of other medical reasons. Finally, 20 (34.5 %) subjects continued to be observed for different reasons. The mean follow-up period after identification of growth was 6.1 years. Nine tumours continued to grow, nine tumours stopped growing, one tumour grew and then regressed in size and one tumour decreased. Sixty percent of patients with useful hearing at diagnosis preserved it during the entire observation period. In conclusion, most of VS do not grow; in case of tumour growth, a surgical procedure may be suggested and the outcomes are not negatively influenced by the delay of the procedure. But in some cases, patients can still follow the "wait and scan" policy. In fact, only less than half of the growing tumours continued to grow. Moreover, most of the patients continued to retain a useful hearing.
authors.affiliation: Department of Specialist Surgical and Anesthesiological Sciences, S. Orsola-Malpighi University Hospital, Via Massarenti 9, 40138 Bologna, Italy. giangaetano.ferri@unibo.it
authors.forename: Gian Gaetano
authors.initials: GG
authors.lastname: Ferri
authors.forename: Antonio
authors.initials: A
authors.lastname: Pirodda
authors.forename: Alberto Rinaldi
authors.initials: AR
authors.lastname: Ceroni
authors.forename: Antonio
authors.initials: A
authors.lastname: Fioravanti
authors.forename: Fabio
authors.initials: F
authors.lastname: Calbucci
authors.forename: Giovanni Carlo
authors.initials: GC
authors.lastname: Modugno
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005682:Gadolinium; D006309:Hearing / Q000502:physiology*; D006320:Hearing Tests; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000473:pathology / Q000628:therapy*
chemical_list: D005682:Gadolinium