title: Molecular characterization of methicillin-sensitive Staphylococcus aureus isolates from bacteremic patients in a Norwegian University Hospital.
abstract: Staphylococcus aureus bacteremia is common in both nosocomial and community settings, and the pathogenicity of the microbe depends upon a large repertoire of virulence factors. S. aureus bacteremia isolates (n = 126) were characterized using DNA microarrays. Clonal complexes 5, 8, 15, 30, and 45 accounted for 74.6% of the isolates. We identified geographical differences in dominating clones and toxin gene profiles. One isolate was methicillin resistant. Potential associations between age and genotype were detected.
authors.affiliation: Department of Microbiology and Infection Control, Akershus University Hospital, Lørenskog, Norway.
authors.forename: Anita
authors.initials: A
authors.lastname: Blomfeldt
authors.forename: Hege Vangstein
authors.initials: HV
authors.lastname: Aamot
authors.forename: Arne N
authors.initials: AN
authors.lastname: Eskesen
authors.forename: Fredrik
authors.initials: F
authors.lastname: Müller
authors.forename: Stefan
authors.initials: S
authors.lastname: Monecke
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000453:epidemiology* / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D016000:Cluster Analysis; D005260:Female; D005798:Genes, Bacterial; D005838:Genotype; D006785:Hospitals, University; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D046228:Microarray Analysis; D008875:Middle Aged; D009664:Norway / Q000453:epidemiology; D020411:Oligonucleotide Array Sequence Analysis; D058974:Phylogeography; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D055815:Young Adult