title: Relationships between dimensions of disability experienced by adults living with HIV: a structural equation model analysis.
abstract: As individuals age with HIV it is increasingly important to consider the health-related consequences of HIV and multiple morbidities, known as disability. We assessed relationships between four dimensions of disability among adults living with HIV. We conducted a structural equation modeling analysis using data from 913 participants in the Ontario HIV Treatment Network Cohort Study to determine relationships between four latent variables of disability in the Episodic Disability Framework: physical symptoms and impairments, mental health symptoms and impairments, difficulties with day-to-day activities, and challenges to social inclusion. Results indicated that physical symptoms and impairments, mental health symptoms and impairments and difficulties with day-to-day activities directly or indirectly predicted challenges to social inclusion for adults living with HIV. Challenges to social inclusion were directly predicted by mental health symptoms and indirectly by physical health symptoms via (mediated by) having difficulties carrying out day-to-day activities and mental health symptoms and impairments. These findings provide a basis for conceptualizing disability experienced by people living with HIV.
authors.affiliation: Department of Physical Therapy, University of Toronto, 500 University Avenue, Room 160, Toronto, M5G 1V7, ON, Canada, kelly.obrien@utoronto.ca.
authors.forename: Kelly K
authors.initials: KK
authors.lastname: O'Brien
authors.forename: Aileen M
authors.initials: AM
authors.lastname: Davis
authors.forename: Sandra
authors.initials: S
authors.lastname: Gardner
authors.forename: Ahmed M
authors.initials: AM
authors.lastname: Bayoumi
authors.forename: Sergio
authors.initials: S
authors.lastname: Rueda
authors.forename: Trevor A
authors.initials: TA
authors.lastname: Hart
authors.forename: Curtis
authors.initials: C
authors.lastname: Cooper
authors.forename: Patricia
authors.initials: P
authors.lastname: Solomon
authors.forename: Sean B
authors.initials: SB
authors.lastname: Rourke
authors.forename: Steven
authors.initials: S
authors.lastname: Hanna
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D006233:Persons with Disabilities / Q000523:psychology*; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology*; D020276:HIV Long-Term Survivors / Q000523:psychology*; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D009864:Ontario; D011788:Quality of Life; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires
chemical_list: D044966:Anti-Retroviral Agents