title: Perinatal occipital lobe injury in children: analysis of twenty-one cases.
abstract: This study used magnetic resonance imaging to analyze causes and clinical courses of pediatric occipital lobe injury. Patients undergoing magnetic resonance imaging for suspected bilateral occipital lobe injury at our Neurodevelopmental Department between July 2007 and June 2011 were included. We evaluated magnetic resonance imaging characteristics, clinical courses, electroencephalogram monitoring, and Denver Development Screen Test scores. Twenty-one infants were examined. Of these, 10 had been born preterm. Thirteen patients demonstrated hypoglycemia. Perinatal period hypoglycemia comprised the most common cause (71.4%) of occipital brain injury. Visual abnormalities were evident in 18 patients. Seventeen (80.9%) patients manifested epilepsy. Infantile spasms were observed in 13 cases (76.5%). According to Denver Development Screen Test assessment, 17 patients demonstrated delayed motor development. Motor function and language improved in 10 patients after effective control of their seizures. Hypoglycemia constitutes the most common cause of occipital injury in infants. Visual impairment, startle episodes, infantile spasms, and motor developmental delay comprise the most common complications, whereas language function is usually spared.
authors.affiliation: Neural Development Department, Bayi Children's Hospital, Military General Hospital of Beijing People's Liberation Army, Beijing, China. wangsanmei66@163.com
authors.forename: San-Mei
authors.initials: SM
authors.lastname: Wang
authors.forename: Chang-Shuan
authors.initials: CS
authors.lastname: Yang
authors.forename: Yu
authors.initials: Y
authors.lastname: Hou
authors.forename: Xiu-Wei
authors.initials: XW
authors.lastname: Ma
authors.forename: Zhi-Chun
authors.initials: ZC
authors.lastname: Feng
authors.forename: Yu-Zhen
authors.initials: YZ
authors.lastname: Liao
mesh_terms: D001930:Brain Injuries / Q000150:complications / Q000473:pathology* / Q000503:physiopathology; D004827:Epilepsy / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009778:Occipital Lobe / Q000293:injuries* / Q000473:pathology / Q000503:physiopathology