title: whole-genome sequence of livestock-associated st398 methicillin-resistant staphylococcus aureus Isolated from Humans in Canada.
abstract: Despite reports of high colonization rates of ST398 livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) among pigs and pig farmers, the incidence of LA-MRSA infection in the general population in Canada appears to be rare in comparison to that in some European countries. In this study, the complete genome sequence of a Canadian representative LA-MRSA isolate (08BA02176) from a human postoperative surgical site infection was acquired and compared to the sequenced genome of an LA-MRSA isolate (S0385) from Europe to identify genetic traits that may explain differences in the success of these particular strains in some locales.
authors.affiliation: National Microbiology Laboratory, Winnipeg, Manitoba, Canada.
authors.forename: George R
authors.initials: GR
authors.lastname: Golding
authors.forename: Louis
authors.initials: L
authors.lastname: Bryden
authors.forename: Paul N
authors.initials: PN
authors.lastname: Levett
authors.forename: Ryan R
authors.initials: RR
authors.lastname: McDonald
authors.forename: Alice
authors.initials: A
authors.lastname: Wong
authors.forename: Morag R
authors.initials: MR
authors.lastname: Graham
authors.forename: Shaun
authors.initials: S
authors.lastname: Tyler
authors.forename: Gary
authors.initials: G
authors.lastname: Van Domselaar
authors.forename: Philip
authors.initials: P
authors.lastname: Mabon
authors.forename: Heather
authors.initials: H
authors.lastname: Kent
authors.forename: Patrick
authors.initials: P
authors.lastname: Butaye
authors.forename: Tara C
authors.initials: TC
authors.lastname: Smith
authors.forename: Kristina
authors.initials: K
authors.lastname: Kadlec
authors.forename: Stefan
authors.initials: S
authors.lastname: Schwarz
authors.forename: Scott J
authors.initials: SJ
authors.lastname: Weese
authors.forename: Michael R
authors.initials: MR
authors.lastname: Mulvey
mesh_terms: D002170:Canada; D004269:DNA, Bacterial / Q000737:chemistry* / Q000235:genetics*; D016680:Genome, Bacterial; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000235:genetics* / Q000302:isolation & purification; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D013203:Staphylococcal Infections / Q000382:microbiology; D013530:Surgical Wound Infection / Q000382:microbiology
chemical_list: D004269:DNA, Bacterial