title: Smoker-nonsmoker differences in neural response to smoking-related and affective cues: an fMRI investigation.
abstract: Smoking may sensitize brain systems to smoking cues while desensitizing systems to naturalistic rewards. This study examined smoker-nonsmoker differences in functional magnetic resonance imaging (fMRI) blood oxygen level dependent (BOLD) response to smoking-related and emotional images. Smokers, relative to nonsmokers, exhibited greater reactivity to smoking and decreased reactivity to emotional cues in the left middle frontal gyrus.
authors.affiliation: Department of Psychology and the Integrative Neuroscience Laboratory, Southern Illinois University, Carbondale, IL, USA. gusdiggs@siu.edu
authors.forename: Herman
authors.initials: H
authors.lastname: Augustus Diggs
authors.forename: Brett
authors.initials: B
authors.lastname: Froeliger
authors.forename: Joshua Michael
authors.initials: JM
authors.lastname: Carlson
authors.forename: David George
authors.initials: DG
authors.lastname: Gilbert
mesh_terms: D000328:Adult; D000339:Affect / Q000502:physiology*; D001921:Brain / Q000503:physiopathology*; D001931:Brain Mapping; D003463:Cues; D059907:Functional Neuroimaging; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D008297:Male; D012201:Reward; D012907:Smoking / Q000503:physiopathology*; D014796:Visual Perception / Q000502:physiology