title: Adaptive functioning and its correlates after intestine and liver transplantation.
abstract: In this cross-sectional study, we compared levels of adaptive functioning and examined potential correlates of adaptive functioning in 18 pediatric intestine (ITX) and 22 liver (LTX) recipients transplanted between June 2003 and March 2009. Family caregivers completed the ABAS-II scale and provided socio-demographic information regarding recipients' age at transplantation, gender, ethnicity, time since transplantation, and caregivers' role, ethnicity, education, and family income. Overall adaptive functioning and all three adaptive functioning subdomain scores were significantly lower in ITX patients compared with LTX patients (p ≤ 0.04) and compared with the general population normative mean (p ≤ 0.003). Significant correlates of adaptive functioning after abdominal transplant included type of transplant procedure (r = -0.4, p = 0.02), gender (r = 0.4, p = 0.01), and educational level of caregiver (r = 0.5, p = 0.003) and together explained 45% of the variance in overall adaptive functioning. Findings provide new information regarding everyday functioning outcomes of ITX patients, add to existing data regarding non-medical outcomes for LTX patients, and highlight the need for ongoing monitoring and intervention following transplantation to enhance outcomes.
authors.affiliation: Department of Pediatric Transplant Surgery, School of Medicine University of Pittsburgh, Pittsburgh, PA, USA. diana.shellmer@chp.edu
authors.forename: Diana A
authors.initials: DA
authors.lastname: Shellmer
authors.forename: Annette
authors.initials: A
authors.lastname: DeVito Dabbs
authors.forename: Mary Amanda
authors.initials: MA
authors.lastname: Dew
authors.forename: Lauren
authors.initials: L
authors.lastname: Terhorst
authors.forename: Robert B
authors.initials: RB
authors.lastname: Noll
authors.forename: Beverly
authors.initials: B
authors.lastname: Kosmach-Park
authors.forename: George
authors.initials: G
authors.lastname: Mazariegos
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology*; D000223:Adaptation, Psychological; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007223:Infant; D007421:Intestine, Small / Q000637:transplantation; D007422:Intestines / Q000637:transplantation*; D008099:Liver / Q000473:pathology; D016031:Liver Transplantation / Q000009:adverse effects / Q000523:psychology*; D008297:Male; D015233:Models, Statistical; D011788:Quality of Life; D012923:Social Class; D013997:Time Factors; D016896:Treatment Outcome