title: Articulating antibiotic impregnated spacers in two-stage revision of infected total knee arthroplasty.
abstract: Antibiotic impregnated articulating spacers are   used in two-stage revision total knee arthroplasty to deliver local antibiotic   therapy while preserving function. We have observed infection control   in greater than 95% of cases with functional outcomes approaching   those seen in revision for aseptic loosening. Higher failure has   been observed with methicillin resistant organisms.
authors.affiliation: University of British Columbia, Department of Orthopaedics, Vancouver, British Columbia V5Z 4E3, Canada. jacobtmunro@gmail.com
authors.forename: J T
authors.initials: JT
authors.lastname: Munro
authors.forename: D S
authors.initials: DS
authors.lastname: Garbuz
authors.forename: B A
authors.initials: BA
authors.lastname: Masri
authors.forename: C P
authors.initials: CP
authors.lastname: Duncan
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation* / Q000379:methods; D001843:Bone Cements; D003131:Combined Modality Therapy; D016503:Drug Delivery Systems; D005500:Follow-Up Studies; D006801:Humans; D007720:Knee Prosthesis / Q000009:adverse effects*; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000601:surgery*; D012086:Reoperation / Q000295:instrumentation / Q000379:methods; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements