title: Racial/ethnic variation in prevalence estimates for United States prediabetes under alternative 2010 American Diabetes Association criteria: 1988-2008.
abstract: OBJECTIVE
  To compare the racial/ethnic variation in United States prediabetes prevalence estimates for alternative prediabetes definitions currently approved by the American Diabetes Association (ADA) across 20 years and in detailed multivariate comparisons.
  
  
  METHODS
  Using nationally representative National Health and Nutrition Examination Survey (NHANES) data from 1988-2008, we compared trends in the prevalence of impaired fasting glucose (IFG) and impaired glycated hemoglobin (IGH) for non-Hispanic Black, non-Hispanic White, and Mexican American/other Hispanic adults. Using NHANES 2005-2008, we compared prevalence by race/ethnicity in more detail for the three current ADA prediabetes definitions--IFG, IGH, and impaired glucose tolerance (IGT)--controlling for associated factors (education, income, weight, age, sex).
  
  
  RESULTS
  Prediabetes prevalence during the last 20 years was consistently significantly lower among non-Hispanic Blacks compared to non-Hispanic Whites when measured by IFG, but was significantly higher among non-Hispanic Blacks when measured by IGH. In adjusted models, non-Hispanic Blacks were significantly more likely than non-Hispanic Whites to have IGH (OR: 2.22; 95% CI: 1.33-3.70) and less likely to have IFG (OR: 0.46; 0.30-0.73) or IGT (OR: 0.35; 0.24-0.50), but Mexican American/other Hispanic rates did not differ significantly from non-Hispanic White rates. However, rates of prediabetes, when defined by any of three individual diagnostic criteria, were not statistically significantly different across groups (36.8% for non-Hispanic Whites, 36.0% AA, 37.3% Mexican American/other Hispanics).
  
  
  CONCLUSIONS
  National prediabetes prevalence estimates vary dramatically across racial/ethnic groups according to diagnostic method, though over 35% in all three racial/ethnic groups met at least one ADA diagnostic criteria for prediabetes.
authors.affiliation: Office of Public Health Studies, University of Hawaii at Manoa, USA.
authors.forename: Tetine L
authors.initials: TL
authors.lastname: Sentell
authors.forename: Guozhong
authors.initials: G
authors.lastname: He
authors.forename: Edward W
authors.initials: EW
authors.lastname: Gregg
authors.forename: Dean
authors.initials: D
authors.lastname: Schillinger
mesh_terms: D001741:Black or African American / Q000706:statistics & numerical data; D001786:Blood Glucose / Q000032:analysis; D006442:Glycated Hemoglobin / Q000032:analysis; D006630:Hispanic or Latino / Q000706:statistics & numerical data; D006801:Humans; D054525:Minority Health; D009749:Nutrition Surveys; D011236:Prediabetic State / Q000208:ethnology*; D015995:Prevalence; D014481:United States / Q000453:epidemiology; D014837:Voluntary Health Agencies; D044465:White People / Q000706:statistics & numerical data
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin