title: Thrombosis incidence in unilateral vs. simultaneous bilateral total knee arthroplasty with compression device prophylaxis.
abstract: This study compares the incidence of venous thromboembolic event (VTE) in 55 patients (110 knees) undergoing simultaneous bilateral TKA with 287 patients (287 knees) undergoing unilateral TKA using a mobile compression device as monotherapy prophylaxis in both groups. All patients were clinically evaluated 3months after surgery with symptomatic confirmed VTE as an endpoint. Deep venous thrombosis (DVT) was documented by duplex ultrasound and pulmonary embolism (PE) was documented by spiral CT. The simultaneous bilateral TKA group had 6 VTEs (10.9%) with 2 PEs (3.6%). The unilateral TKA group had 9 VTEs (3.1%), and 0 PE. Patients undergoing simultaneous bilateral TKA yielded more than twice the rate of VTE compared with patients undergoing unilateral TKA using a mobile compression device as sole thromboprophylactic modality.
authors.affiliation: Shiley Center for Orthopaedic Research & Education at Scripps Clinic, La Jolla, California, USA.
authors.forename: Yadin D
authors.initials: YD
authors.lastname: Levy
authors.forename: Mary E
authors.initials: ME
authors.lastname: Hardwick
authors.forename: Steven N
authors.initials: SN
authors.lastname: Copp
authors.forename: Adam S
authors.initials: AS
authors.lastname: Rosen
authors.forename: Clifford W
authors.initials: CW
authors.lastname: Colwell
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015994:Incidence; D048228:Intermittent Pneumatic Compression Devices; D008297:Male; D012189:Retrospective Studies; D054556:Venous Thromboembolism / Q000209:etiology / Q000517:prevention & control*