title: [Regional analysis of drug treatment prevalence and medication  of diabetes mellitus in Germany].
abstract: OBJECTIVE
  Diabetes mellitus is a widespread chronic disease. Diabetes prevalence was already analyzed in multiple complex studies. The goal of this analysis was the determination of the regional drug treatment prevalence and medication of diabetes mellitus in Germany. Simultaneously, we examined and validated the applicability of prescription data of the German statutory health insurance (SHI) as the basis for reliable and comparable prevalence estimations.
  
  
  METHODS
  For the analysis, we used anonymized data from a prescription database as well as the member statistics of the German federal Ministry of Health. By using defined prescription profiles with anti-diabetic medication, we determined the diabetic patients and treatment schemes per Association of SHI Physicians. Subsequently, we calculated and described the drug treatment prevalence and medication. A differentiation between type 1 and type 2 diabetes was not possible.
  
  
  RESULTS
  The total prevalence of drug-treated patients in Germany was 7.77%. The regional values ranged from 6.40% in Schleswig-Holstein until 11.37% in Saxony-Anhalt. The highest numbers of drug treatment prevalence were found in the East of Germany. Insulin treatment was frequent in Hamburg, but rare in Bavaria. Insulin combined with oral anti-diabetic medication was mainly dispensed in Saxony-Anhalt and Brandenburg, least in Hamburg. A treatment with one or more oral anti-diabetics was most common in Bavaria and Bremen, lowest in Rhineland-Palatinate and Mecklenburg-West Pomerania.
  
  
  CONCLUSIONS
  We developed an easy to use evaluation algorithm for prescription data to estimate the drug treatment prevalence of a chronic disease. The estimated prevalence confirms the increasing trend reported from other studies and appears to be plausible in comparison. More research is required to validate and enhance the method.
authors.affiliation: GECKO Institut für Medizin, Informatik und Ökonomie der Hochschule Heilbronn. thomas.willert@hs-heilbronn.de
authors.forename: T
authors.initials: T
authors.lastname: Willert
authors.forename: J
authors.initials: J
authors.lastname: Walker
authors.forename: W
authors.initials: W
authors.lastname: Schramm
mesh_terms: D003920:Diabetes Mellitus / Q000188:drug therapy* / Q000453:epidemiology*; D062306:Geography, Medical; D005858:Germany / Q000453:epidemiology; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D055656:Prescriptions / Q000706:statistics & numerical data*; D015995:Prevalence; D012041:Regional Medical Programs / Q000706:statistics & numerical data*
chemical_list: D007004:Hypoglycemic Agents