title: Dynamic transmission of West Nile virus across the United States-Mexican border.
abstract: Confirmed clinical and veterinary cases of West Nile virus (WNV) infection in Mexico remain restricted to northern Mexico, supporting a unidirectional transmission model from the US into Mexico. Full-length genomic sequencing of nine WNV isolates obtained from Culex spp. mosquito pools in El Paso, Texas (n=7) and Cuidad Juarez, Mexico (n=2) from 2005 to 2010 demonstrates the co-circulation of three independent genetic groups, two of which belong to the southwestern (SW/WN03) genotype and the other to the North American (NA/WN02) genotype. These results indicate ongoing dynamic circulation of WNV between the United States and Mexico.
authors.affiliation: Department of Pathology, Center for Biodefense and Emerging Infectious Diseases, and Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, Texas 77555-0436, USA.
authors.forename: Brian R
authors.initials: BR
authors.lastname: Mann
authors.forename: Allison R
authors.initials: AR
authors.lastname: McMullen
authors.forename: Hilda
authors.initials: H
authors.lastname: Guzman
authors.forename: Robert B
authors.initials: RB
authors.lastname: Tesh
authors.forename: Alan D T
authors.initials: AD
authors.lastname: Barrett
mesh_terms: D019943:Amino Acid Substitution; D000818:Animals; D003465:Culex / Q000821:virology*; D014644:Genetic Variation; D005838:Genotype; D006801:Humans; D007303:Insect Vectors / Q000821:virology; D008800:Mexico; D010802:Phylogeny; D017423:Sequence Analysis, RNA; D013781:Texas; D014481:United States; D014901:West Nile Fever / Q000635:transmission* / Q000662:veterinary / Q000821:virology; D014902:West Nile virus / Q000235:genetics* / Q000302:isolation & purification