title: Molecular dissection of the basal clades in the human Y chromosome phylogenetic tree.
abstract: One hundred and forty-six previously detected mutations were more precisely positioned in the human Y chromosome phylogeny by the analysis of 51 representative Y chromosome haplogroups and the use of 59 mutations from literature. Twenty-two new mutations were also described and incorporated in the revised phylogeny. This analysis made it possible to identify new haplogroups and to resolve a deep trifurcation within haplogroup B2. Our data provide a highly resolved branching in the African-specific portion of the Y tree and support the hypothesis of an origin in the north-western quadrant of the African continent for the human MSY diversity.
authors.affiliation: Dipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza Università di Roma, Rome, Italy.
authors.forename: Rosaria
authors.initials: R
authors.lastname: Scozzari
authors.forename: Andrea
authors.initials: A
authors.lastname: Massaia
authors.forename: Eugenia
authors.initials: E
authors.lastname: D'Atanasio
authors.forename: Natalie M
authors.initials: NM
authors.lastname: Myres
authors.forename: Ugo A
authors.initials: UA
authors.lastname: Perego
authors.forename: Beniamino
authors.initials: B
authors.lastname: Trombetta
authors.forename: Fulvio
authors.initials: F
authors.lastname: Cruciani
mesh_terms: D041322:Chromosomes, Human, Y / Q000235:genetics*; D015894:Genome, Human; D006239:Haplotypes / Q000235:genetics*; D006801:Humans; D018895:Microsatellite Repeats / Q000235:genetics; D009154:Mutation; D010802:Phylogeny; D020641:Polymorphism, Single Nucleotide