title: [Biochemical markers in assessment of severity and prognosis of acute pancreatitis].
abstract: The authors reveal and discuss the role of novel biochemical parameters in early diagnosis of acute pancreatitis and assessment of the severity of the disease. These biochemical parameters, beside routinely used amilase and lipase, might enable us to early identify those patients who are at risk of developing severe form of pancreatitis or complications. These parameters include trypsinogen activation peptide (TAP), C-reactive protein (CRP, tripsinogen-2, procalcitonin, phospholipase-A2 (PLA2), carboxypeptidase activation peptide (CAPAP) and interleukin-6 and 8 (IL-6, IL-8). Although these markers are still not incorporated in routine clinical practice, IL-6, IL-10, procalcitonin and trypsinogen activation peptide seem to have a good chance to be used as a new biochemical markers in assessment of severity and prognosis of acute pancreatitis.
authors.affiliation: Zavod za gastroenterologiju i hepatologiju, KB Dubrava, Av. Gojka SuSka 6, 10 000 Zagreb.
authors.forename: Lidija
authors.initials: L
authors.lastname: Petricusić
authors.forename: Marko
authors.initials: M
authors.lastname: Banić
authors.forename: Zeljko
authors.initials: Z
authors.lastname: Cabrijan
authors.forename: Marija
authors.initials: M
authors.lastname: Urek-Crncević
authors.forename: Vanja
authors.initials: V
authors.lastname: Hulak-Karlak
authors.forename: Ivica
authors.initials: I
authors.lastname: Grgurević
mesh_terms: D000208:Acute Disease; D015415:Biomarkers / Q000032:analysis*; D006801:Humans; D010195:Pancreatitis / Q000175:diagnosis*; D011379:Prognosis
chemical_list: D015415:Biomarkers