title: α-Aryl-substituted allenamides in an imino-Nazarov cyclization cascade catalyzed by Au(I).
abstract: An imino-Nazarov cyclization using α-aryl-substituted allenamides is described. This gold(I)-catalyzed cascade is efficient and regioselective in constructing a diverse array of synthetically useful aromatic-ring fused cyclopentenamides. The success in this transformation represents a solution to the challenge in establishing an imino-Nazarov cyclization process.
authors.affiliation: Division of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin, Madison, Wisconsin 53705, USA.
authors.forename: Zhi-Xiong
authors.initials: ZX
authors.lastname: Ma
authors.forename: Shuzhong
authors.initials: S
authors.lastname: He
authors.forename: Wangze
authors.initials: W
authors.lastname: Song
authors.forename: Richard P
authors.initials: RP
authors.lastname: Hsung
mesh_terms: D000466:Alkadienes / Q000737:chemistry; D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000737:chemistry; D017612:Gold Compounds / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000466:Alkadienes; D000577:Amides; D003517:Cyclopentanes; D017612:Gold Compounds; C038016:gold chloride