title: Depression and cardiovascular disease: the end of simple models.
abstract: In this editorial, we propose that the association between depression and cardiovascular disease may be conceptualised as a continuous, bidirectional process that originates in youth. The paper byÅberg and colleagues in this issue adds to this literature showing that low cardiovascular fitness at adolescence increases the risk of future depression.
authors.forename: Peter
authors.initials: P
authors.lastname: de Jonge
authors.forename: Annelieke M
authors.initials: AM
authors.lastname: Roest
mesh_terms: D002320:Cardiovascular Physiological Phenomena; D003866:Depressive Disorder / Q000209:etiology*; D006801:Humans; D008297:Male; D010809:Physical Fitness / Q000523:psychology*