title: Two new diterpenes, neocaesalpin MR and minaxin C, from Caesalpinia minax.
abstract: Two new cassane-type diterpenes, neocaesalpin MR and minaxin C, were isolated from Caesalpinia minax HANCE. The structures of these compounds were elucidated by means of spectroscopic analysis. Among these isolated compounds, neocaesalpin MR showed mild activities toward HeLa and colon cancer (HCT-8) human cancer cell lines.
authors.affiliation: Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China.
authors.forename: Guo-Xu
authors.initials: GX
authors.lastname: Ma
authors.forename: Na
authors.initials: N
authors.lastname: Xu
authors.forename: Jing-Quan
authors.initials: JQ
authors.lastname: Yuan
authors.forename: Hua
authors.initials: H
authors.lastname: Wei
authors.forename: Qing-Xia
authors.initials: QX
authors.lastname: Zheng
authors.forename: Zhao-Cui
authors.initials: ZC
authors.lastname: Sun
authors.forename: Jun-Shan
authors.initials: JS
authors.lastname: Yang
authors.forename: Xu-Dong
authors.initials: XD
authors.lastname: Xu
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D029911:Caesalpinia / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes; D004365:Drugs, Chinese Herbal; C578216:minaxin C; C578215:neocaesalpin MR