title: Analysis of procedure-related complications after pancreatodoudenectomy.
abstract: OBJECTIVE
  To analyze the procedure-related complications after pancreaticoduodenctomy (PD) and their risk factors.
  
  
  METHODS
  One hundred twenty-six patients underwent pancreatoduodenectomy for diseases at region of pancreatic head were reviewed retrospectively.
  
  
  RESULTS
  The overall surgical morbidity was 40.5% (51/126). Ten (7.9%) of 51 patients were identified as having pancreatic leakage, others included delayed gastric emptying (8.7%, 11), abdominal infection and abscess (7.9%, 10), abdominal bleeding (5.6%, 7), wound infection (4.8%, 6), wound dehiscence (2.4%, 3), biliary fistula (1.6%, 2) and operative death (1.6%, 2). Other postoperative complications were lung inflammation (3.9%, 5) and newly developed diabetes mellitus (2.3%, 3). Age (>60 years), coexisting diabetes mellitus, small main pancreatic duct (≤0.5 cm), and surgeon's experience (<10 patients within 5 years) were demonstrated to be independent risk factors by both univariate and multivariate analysis (p < 0.01).
  
  
  CONCLUSIONS
  Old patients with coexisting diabetes mellitus and small main pancreatic duct undergo pancreatoduodenectomy by a less experienced surgeon may be at high risk of procedure-related complications.
authors.affiliation: Department of General Surgery, Wenzhou Medical College, Wenzhou, 325 000 Zhejiang Province, PR China.
authors.forename: Shao-Liang
authors.initials: SL
authors.lastname: Han
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Zheng
authors.forename: Xian
authors.initials: X
authors.lastname: Shen
authors.forename: Zhi
authors.initials: Z
authors.lastname: Liu
authors.forename: Jun-Lin
authors.initials: JL
authors.lastname: Li
authors.forename: Sheng-Hong
authors.initials: SH
authors.lastname: Lan
authors.forename: Guan-Bao
authors.initials: GB
authors.lastname: Zhu
keywords: Complication; Pancreatic leakage; Pancreaticoduodenectomy