title: Molecular characterization of a Korean bovine parainfluenza virus type 3 isolate.
abstract: Bovine parainfluenza virus type 3 (BPIV-3) was isolated from Korean native cattle that presented clinical signs of mild pneumonia. The complete genome of a representative isolate (12Q061) was sequenced. The newly identified strain, which was found to be distinct from the previously reported genotypes A (BPIV-3a) and B (BPIV-3b) and closely related to the Chinese strain SD0835, was tentatively classified as genotype C (BPIV-3c). Our results suggest a relationship between BPIV-3 genetic variation and the geographic location of its isolation. Identification of these new BPIV-3 genotypes may facilitate the development of improved diagnostic methods and vaccines. This is to our knowledge the first report of the identification and molecular characterization of BPIV-3 in Korea.
authors.affiliation: Animal Disease Diagnostic Division, Animal, Plant and Fisheries Quarantine and Inspection Agency, 480 Anyang-6-Dong, Anyang 430-824, Republic of Korea.
authors.forename: Jae-Ku
authors.initials: JK
authors.lastname: Oem
authors.forename: Eun-Yong
authors.initials: EY
authors.lastname: Lee
authors.forename: Kyoung-Ki
authors.initials: KK
authors.lastname: Lee
authors.forename: Seong-Hee
authors.initials: SH
authors.lastname: Kim
authors.forename: Myoung-Heon
authors.initials: MH
authors.lastname: Lee
authors.forename: Bang-Hun
authors.initials: BH
authors.lastname: Hyun
mesh_terms: D000818:Animals; D001483:Base Sequence; D002417:Cattle; D002418:Cattle Diseases / Q000821:virology*; D014644:Genetic Variation; D016679:Genome, Viral; D005838:Genotype; D029101:Parainfluenza Virus 3, Bovine / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D010802:Phylogeny; D011024:Pneumonia, Viral / Q000662:veterinary* / Q000821:virology; D056910:Republic of Korea; D010253:Respirovirus Infections / Q000662:veterinary* / Q000821:virology