title: [The activity of osteoclast in peri-implant tissues in Beagle dogs].
abstract: OBJECTIVE
  To observe the quantity and activity of osteoclast in peri-implant tissues dynamically.
  
  
  METHODS
  An animal model of dental implants was established in 6 male Beagle dogs of 1-2 years old. Bone remodeling was tested at 3-, 7-,15-,30-,60- and 90-day after placement of implants. The mandibular bones were taken out and the morphological changes were observed under X-ray examination.Bone tissue samples underwent HE staining. The data were analyzed with SPSS13.0 software package.
  
  
  RESULTS
  The most prominent period of osteoclasts occurred at 7-day after placement of implants. After 7 days of implantation, the activity of osteoclast gradually decreased.
  
  
  CONCLUSIONS
  The active stage for bone remodelling in peri-implant tissues during unloading period is about 7 days after implantation.
authors.affiliation: Department of Dental Implantation Centre, Yantai Stomatological Hospital, Yantai, Shandong Province, China.
authors.forename: Zhong-hao
authors.initials: ZH
authors.lastname: Liu
authors.forename: Wen-juan
authors.initials: WJ
authors.lastname: Zhou
authors.forename: Peng-jie
authors.initials: PJ
authors.lastname: Hao
authors.forename: Zhi-shan
authors.initials: ZS
authors.lastname: Lu
authors.forename: Lei
authors.initials: L
authors.lastname: Meng
authors.forename: Ai-jie
authors.initials: AJ
authors.lastname: Sun
mesh_terms: D000818:Animals; D016723:Bone Remodeling; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D004285:Dogs; D008297:Male; D008334:Mandible; D010010:Osteoclasts
chemical_list: D015921:Dental Implants