title: [Postoperative pain trajectories to identify risk of chronic postsurgical pain in living donors for liver transplantation].
abstract: OBJECTIVE
  To assess pain trajectories in predicting risk of chronic postoperative pain (CPP) after liver resection for living donor transplantation.
  
  
  METHODS
  Retrospective analysis of patients undergoing liver resection for living donor transplantation during 3years.
  
  
  METHODS
  After recording perioperative data, patients presenting CPP at 3months were separated from patients without postsurgical pain problem in order to build a pain trajectory for liver donor patients without CPP. Postoperative course of liver donors with CPP was then compared to that standard pain trajectory.
  
  
  RESULTS
  Sixty-five patients (30 females, 35 males) were included. Epidural analgesia was used in 66%; others received autocontrolled analgesia by morphine. Severe acute pain was expressed by 11% and 37% at rest and movement respectively on the first day. Chronic pain involved six patients without any link with gender or type of analgesia. Analysis of pain trajectories shown that these patients presented either higher initial pain at day 1 or positive slopes with worsening of pain.
  
  
  CONCLUSIONS
  Acute postoperative pain is a risk factor of developing CPP. Identification of those people by pain trajectories can be useful to treat them early.
authors.affiliation: Département d'anesthésie-réanimation, hôpital de la Croix-Rousse, hospices civils de Lyon, 104 grande rue de la Croix-Rousse, Lyon, France. aurelie.bonnet@chu-lyon.fr
authors.forename: A
authors.initials: A
authors.lastname: Bonnet
authors.forename: P
authors.initials: P
authors.lastname: Lavand'homme
authors.forename: M-N
authors.initials: MN
authors.lastname: France
authors.forename: R
authors.initials: R
authors.lastname: Reding
authors.forename: M
authors.initials: M
authors.lastname: De Kock
mesh_terms: D000328:Adult; D015360:Analgesia, Epidural; D016058:Analgesia, Patient-Controlled; D000701:Analgesics, Opioid / Q000627:therapeutic use; D002908:Chronic Disease; D059350:Chronic Pain / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects; D006801:Humans; D008099:Liver / Q000601:surgery*; D016031:Liver Transplantation; D019520:Living Donors / Q000706:statistics & numerical data*; D008297:Male; D009020:Morphine / Q000627:therapeutic use; D010147:Pain Measurement; D010149:Postoperative Pain / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D017060:Patient Satisfaction; D012189:Retrospective Studies; D018570:Risk Assessment; D012737:Sex Factors
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine