title: Mixture of ether and silicone oil for the treatment of inferior complicated retinal detachment.
abstract: OBJECTIVE
  To report the efficacy and ocular tolerance of a new tamponade made with ether and silicone oil (HeavySil [HSIL]) for the treatment of retinal detachment (RD) complicated by inferior proliferative vitreous retinopathy (PVR).
  
  
  METHODS
  Prospective noncomparative interventional study on 31 consecutive eyes that underwent pars plana vitrectomy and were treated with HSIL as an intraocular tamponade. All patients presented with at least one retinal break and grade B-C PVR located between 4 and 8 o'clock. The main endpoint criteria were retinal reattachment after the removal of HSIL and complications arisen from the use of this tamponade.
  
  
  RESULTS
  Primary anatomic success was achieved in 27 out of 31 cases. Mean visual acuity improved from logMAR 1.4 (SD 0.7) to logMAR 1.1 (SD 0.6) (p=0.02). The main complications reported were cataract formation (5 out of 7 phakic eyes cases), clinically visible emulsification (6 cases), and difficulty of oil removal in 3 cases. Severe intraocular inflammation with HSIL in situ was found in only one case.
  
  
  CONCLUSIONS
  HeavySil, a saturated solution of ether with silicone oil, is a safe and effective tamponade agent for the treatment of complicated RD. The most common complications are cataract formation and oil emulsification.
authors.affiliation: Istituto Clinico Humanitas, Rozzano, Milan, Italy. romanomario@email.it
authors.forename: Mario R
authors.initials: MR
authors.lastname: Romano
authors.forename: Stefano
authors.initials: S
authors.lastname: Zenoni
authors.forename: Paolo
authors.initials: P
authors.lastname: Arpa
authors.forename: Cesare
authors.initials: C
authors.lastname: Mariotti
mesh_terms: D004322:Drainage / Q000379:methods; D004338:Drug Combinations; D058450:Endotamponade; D004986:Ether / Q000737:chemistry; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012163:Retinal Detachment / Q000209:etiology / Q000601:surgery*; D012827:Silicone Oils / Q000008:administration & dosage* / Q000009:adverse effects / Q000737:chemistry; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy; D018630:Vitreoretinopathy, Proliferative / Q000150:complications
chemical_list: D004338:Drug Combinations; D012827:Silicone Oils; C515608:densiron; D004986:Ether