title: Echogenic splenic lesions in a child with type B Niemann-Pick disease.
abstract: We report the case of a 15-year-old boy with Niemann-Pick disease type B with characteristic sonographic findings of splenic involvement. There were multiple well-defined echogenic nodular lesions within the spleen parenchyma, and these lesions were surrounded by ring-like blood flow on color Doppler imaging. Most of the patients with Niemann-Pick disease type B are children and they undergo repeated imaging studies. Therefore, familiarity with sonographic findings of the disease is required.
authors.affiliation: Department of Radiology, Dicle University, School of Medicine, Diyarbakir 21280, Turkey.
authors.forename: Mehmet Emin
authors.initials: ME
authors.lastname: Adin
authors.forename: Hakan
authors.initials: H
authors.lastname: Onder
authors.forename: Ulaş
authors.initials: U
authors.lastname: Alabalık
mesh_terms: D000293:Adolescent; D006801:Humans; D008297:Male; D052537:Niemann-Pick Disease, Type B / Q000000981:diagnostic imaging*; D013158:Splenic Diseases / Q000000981:diagnostic imaging*; D018615:Ultrasonography, Doppler, Color
keywords: Niemann-Pick disease; color Doppler ultrasonography; spleen; ultrasound