title: Alterations of the cerebral white matter in a middle-aged patient with turner syndrome: an MRI study.
abstract: A 52-year-old woman with intellectual disability was admitted to the hospital due to pneumonia. MRI of her brain showed diffuse hyperintensities on T(2)-weighted and fluid attenuated inversion recovery images in the bilateral cerebral white matter. Laboratory examination revealed sustained high levels of serum KL-6. Karyotyping revealed partial monosomy of the X chromosome. This is the first case showing diffuse white matter lesions in the brain, and sustained high levels of serum KL-6 in Turner syndrome.
authors.affiliation: Department of Neurology, Hematology, Metabolism, Endocrinology and Diabetology (DNHMED), Yamagata University School of Medicine, Yamagata, Japan.
authors.forename: Haruko
authors.initials: H
authors.lastname: Tanji
authors.forename: Katsuo
authors.initials: K
authors.lastname: Nakajima
authors.forename: Manabu
authors.initials: M
authors.lastname: Wada
authors.forename: Takeo
authors.initials: T
authors.lastname: Kato
keywords: KL-6; MRI; Turner syndrome; White matter lesion