title: Clinical features and surgical outcomes of complete transposition of the great arteries.
abstract: OBJECTIVE
  This single-center study aimed to assess the clinical features and surgical approaches and outcomes of complete transposition of the great arteries (TGA).
  
  
  METHODS
  TGA patients who had undergone surgical correction at the Kyungpook National University Hospital from January 2000 to December 2010, were retrospectively evaluated for patient characteristics, clinical manifestation, preoperative management, intraoperative findings, postoperative progress, and follow-up status.
  
  
  RESULTS
  Twenty-eight patients (17 boys and 11 girls, mean age=10.6±21.5 days) were included and were categorized as follows: group I, TGA with intact ventricular septum (n=13); group II, TGA with ventricular septal defect (VSD, n=12); and group III, TGA/VSD with pulmonary stenosis (n=3). Group I underwent the most intensive preoperative management (balloon atrial septostomy and prostaglandin E1 medication). Group II showed the highest incidence of heart failure (P<0.05). Usual and unusual coronary anatomy patterns were observed in 20 (71%) and 8 patients, respectively. Arterial and half-turned truncal switch operations were performed in 25 and 3 patients (Group III), respectively. Postoperative complications included cardiac arrhythmias (8 patients), central nervous system complications (3 patients), acute renal failure (1 patient), infections (3 patients), and cardiac tamponade (1 patient), and no statistically significant difference was observed between the groups. Group II showed the mildest aortic regurgitation on follow-up echocardiograms (P<0.05). One patient underwent reoperation, and 1 died. The overall mortality rate was 4%.
  
  
  CONCLUSIONS
  Our study showed favorable results in all the groups and no significant difference in postoperative complication, reoperation, and mortality among the groups. However, our results were inadequate to evaluate the risk factors for reoperation and mortality owing to the small number of patients and short follow-up duration.
authors.affiliation: Department of Pediatrics, Kyungpook National University School of Medicine, Daegu, Korea.
authors.forename: Suk Jin
authors.initials: SJ
authors.lastname: Hong
authors.forename: Hee Joung
authors.initials: HJ
authors.lastname: Choi
authors.forename: Yeo Hyang
authors.initials: YH
authors.lastname: Kim
authors.forename: Myung Chul
authors.initials: MC
authors.lastname: Hyun
authors.forename: Sang Bum
authors.initials: SB
authors.lastname: Lee
authors.forename: Joon Yong
authors.initials: JY
authors.lastname: Cho
keywords: Dextro-looped transposition of the great arteries; Mortality; Postoperative complications; Reoperation