title: Association between obesity indices and cardiovascular risk factors in late adolescence in the Seychelles.
abstract: BACKGROUND
  The ability of different obesity indices to predict cardiovascular risk is still debated in youth and few data are available in sub Saharan Africa. We compared the associations between several indices of obesity and cardiovascular risk factors (CVRFs) in late adolescence in the Seychelles.
  
  
  METHODS
  We measured body mass index (BMI), waist circumference, waist/hip ratio (WHiR), waist/height ratio (WHtR) and percent fat mass (by bioimpedance) and 6 CVRFs (blood pressure, LDL-cholesterol, HDL-cholesterol, triglycerides, fasting blood glucose and uric acid) in 423 youths aged 19-20 years from the general population.
  
  
  RESULTS
  The prevalence of overweight/obesity and several CVRFs was high, with substantial sex differences. Except for glucose in males and LDL-cholesterol in females, all obesity indices were associated with CVRFs. BMI consistently predicted CVRFs at least as well as the other indices. Linear regression on BMI had standardized regression coefficients of 0.25-0.36 for most CVRFs (p<0.01) and ROC analysis had an AUC between 60%-75% for most CVRFs. BMI also predicted well various combinations of CVRFs: 36% of male and 16% of female lean subjects (BMI <P50) had ≥2 CVRFs compared to 74% of male and 46% of female overweight subjects (BMI >P90).
  
  
  CONCLUSIONS
  There was an elevated prevalence of obesity and of several CVRFs in youths in Seychelles. BMI predicted single or combined CVRFs at least as well as other simple obesity indices.
authors.affiliation: Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Lausanne, Switzerland. pascal.bovet@chuv.ch
authors.forename: Pascal
authors.initials: P
authors.lastname: Bovet
authors.forename: Tiphaine
authors.initials: T
authors.lastname: Arlabosse
authors.forename: Bharathi
authors.initials: B
authors.lastname: Viswanathan
authors.forename: Gary
authors.initials: G
authors.lastname: Myers
mesh_terms: D000293:Adolescent; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D012750:Seychelles / Q000453:epidemiology; D055815:Young Adult