title: Synthesis and characterization of some new Schiff base complexes of group 13 elements, ab initio studies, cytotoxicity and reaction with hydrogen peroxide.
abstract: A novel tetradentate Schiff base, naphthabza-H2=N,N'-bis(naphthylidene)-2-aminobenzylamine, and a series of aluminum(III), gallium(III), and indium(III) complexes with general formula, MLNO3, were synthesized and characterized by elemental analysis, 1H NMR, FT-IR, UV-Vis spectroscopy and thermogravimetric method. The product of the reaction of complexes with hydrogen peroxide was characterized by similar techniques. According to the ab initio calculations aluminum and gallium complexes have five-coordinated structures and indium complex is a six-coordinated one. Also, the growth inhibitory effects of the complexes toward K562 cancer cell line were measured and the results for these complexes are as follows: Al>Ga>In.
authors.affiliation: Department of Chemistry, College of Science, Shiraz University, Shiraz 71454, Iran. asadi@susc.ac.ir
authors.forename: Mozaffar
authors.initials: M
authors.lastname: Asadi
authors.forename: Nooshin
authors.initials: N
authors.lastname: Savaripoor
authors.forename: Zahra
authors.initials: Z
authors.lastname: Asadi
authors.forename: Mohammad Hadi
authors.initials: MH
authors.lastname: Ghatee
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Moosavi
authors.forename: Reza
authors.initials: R
authors.lastname: Yousefi
authors.forename: Mehrnaz
authors.initials: M
authors.lastname: Jamshidi
mesh_terms: D000535:Aluminum / Q000737:chemistry* / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D001596:Benzylamines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D005708:Gallium / Q000737:chemistry* / Q000494:pharmacology; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism; D007204:Indium / Q000737:chemistry* / Q000494:pharmacology; D008958:Models, Molecular; D009369:Neoplasms / Q000188:drug therapy; D012545:Schiff Bases / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D001596:Benzylamines; D056831:Coordination Complexes; D012545:Schiff Bases; D007204:Indium; D006861:Hydrogen Peroxide; D005708:Gallium; D000535:Aluminum