title: Hyperreflective dots surrounding the central retinal artery and vein in optic disc melanocytoma revealed by spectral domain optical coherence tomography.
abstract: OBJECTIVE
  To report findings of optic disc melanocytoma (ODM) obtained using spectral domain optical coherence tomography (SD OCT), with special reference to the central retinal artery and vein surrounded by hyperreflective dots.
  
  
  METHODS
  Retrospective review of five eyes of five patients with ODM. Demographic information, ophthalmic examination including best-corrected visual acuity, dilated funduscopic examination, and SD OCT images were evaluated.
  
  
  RESULTS
  Dome-shaped, darkly pigmented tumors were seen ophthalmoscopically in the optic discs of all eyes. On OCT, the first branches of the central retinal artery and/or vein were well defined as oblique sections of tubular structures with a perivascular distribution of hyperreflective dots in the elevated retina (nerve fiber layer) over the tumor. The portions where these vessels turn toward the retina were displaced more anteriorly than those of eyes without ODM. Hyperreflective dots of various sizes were also observed in elevated retinas over the tumors, which shadowed and obscured the subjacent tissue in all eyes.
  
  
  CONCLUSIONS
  SD OCT provides higher definition images of ODM relating to the branches of the central retinal artery/vein, revealing anterior displacement of vessels and perivascular distribution of hyperreflective dots that suggest melanophages and/or tumor cells or proteins and/or lipid deposits.
authors.affiliation: Unoki Eye Clinic, 1-7-15 Harara, Kagoshima, Kagoshima 890-0026, Japan. akiko@m2.kufm.kagoshima-u.ac.jp
authors.forename: Akiko
authors.initials: A
authors.lastname: Okubo
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Unoki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yoshikawa
authors.forename: Tatsuro
authors.initials: T
authors.lastname: Ishibashi
authors.forename: Munefumi
authors.initials: M
authors.lastname: Sameshima
authors.forename: Taiji
authors.initials: T
authors.lastname: Sakamoto
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009508:Nevus, Pigmented / Q000175:diagnosis*; D009887:Ophthalmoscopy / Q000379:methods; D009898:Optic Disk / Q000473:pathology*; D012161:Retinal Artery; D019572:Retinal Neoplasms / Q000175:diagnosis*; D012169:Retinal Vein; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*