title: Benzophenone and xanthone derivatives from the inflorescences of Garcinia cowa.
abstract: The purification of the acetone extract from the inflorescences of Garcinia cowa led to the isolation of a new benzophenone derivative, cowanone (1), together with seven known xanthones, α-mangostin (2), β-mangostin (3), cowanin (4), fuscaxanthone A (5), 9-hydroxycalabaxanthone (6), garcinianone A (7) and cowanol (8). The structures of the isolated compounds were elucidated by analysis of their spectroscopic data including 1D and 2D NMR data. All isolated compounds were evaluated for their antibacterial activities against Staphylococcus aureus (SA) and methicillin-resistant S. aureus (MRSA).
authors.affiliation: Department of Chemistry, Faculty of Science, Chiang Mai University, Muang, Thailand.
authors.forename: Kongkiat
authors.initials: K
authors.lastname: Trisuwan
authors.forename: Thunwadee
authors.initials: T
authors.lastname: Ritthiwigrom
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001577:Benzophenones / Q000302:isolation & purification* / Q000494:pharmacology; D029760:Garcinia / Q000737:chemistry*; D056626:Inflorescence / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus / Q000187:drug effects; D013329:Structure-Activity Relationship; D044004:Xanthones / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D001577:Benzophenones; D044004:Xanthones