title: Marine cyanobacterial fatty acid amides acting on cannabinoid receptors.
abstract: Striking cAMP: certain fatty acid amides from marine cyanobacteria can mimic the endocannabinoids. Serinolamide B, a new analogue identified from a Guamanian sample, and malyngamide B, a representative member of a large class of cyanobacterial metabolites, can decrease forskolin-induced cAMP accumulation through the cannabinoid receptors.
authors.affiliation: Department of Medicinal Chemistry, University of Florida, Gainesville, 32610, USA.
authors.forename: Rana
authors.initials: R
authors.lastname: Montaser
authors.forename: Valerie J
authors.initials: VJ
authors.lastname: Paul
authors.forename: Hendrik
authors.initials: H
authors.lastname: Luesch
mesh_terms: D000577:Amides / Q000737:chemistry*; D000818:Animals; D059001:Aquatic Organisms / Q000737:chemistry*; D040761:Biomimetic Materials / Q000737:chemistry / Q000494:pharmacology; D063386:Cannabinoid Receptor Agonists / Q000737:chemistry / Q000494:pharmacology; D063387:Cannabinoid Receptor Antagonists / Q000737:chemistry / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D000458:Cyanobacteria / Q000737:chemistry*; D005227:Fatty Acids / Q000737:chemistry* / Q000494:pharmacology*; D019073:HT29 Cells; D006801:Humans; D061986:MCF-7 Cells; D051379:Mice; D043882:Receptors, Cannabinoid / Q000378:metabolism*
chemical_list: D000577:Amides; D063386:Cannabinoid Receptor Agonists; D063387:Cannabinoid Receptor Antagonists; D005227:Fatty Acids; D043882:Receptors, Cannabinoid