title: Colonization dynamics of antibiotic-resistant coagulase-negative Staphylococci in neonates.
abstract: Coagulase-negative staphylococci (CoNS) isolated in neonatal late-onset sepsis are often antibiotic resistant. We analyzed CoNS from skin and feces of neonates during hospitalization. Antibiotic resistance of skin isolates increased during hospitalization, especially in Staphylococcus haemolyticus. Staphylococcus warneri showed low antibiotic resistance. Our data suggest that different CoNS species may play distinct roles in colonization.
authors.affiliation: Department of Pediatrics, Erasmus MC–Sophia Children’s Hospital, Rotterdam, The Netherlands.
authors.forename: Vishal
authors.initials: V
authors.lastname: Hira
authors.forename: René F
authors.initials: RF
authors.lastname: Kornelisse
authors.forename: Marcel
authors.initials: M
authors.lastname: Sluijter
authors.forename: Alike
authors.initials: A
authors.lastname: Kamerbeek
authors.forename: Wil H F
authors.initials: WH
authors.lastname: Goessens
authors.forename: Ronald
authors.initials: R
authors.lastname: de Groot
authors.forename: Peter W M
authors.initials: PW
authors.lastname: Hermans
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015373:Bacterial Typing Techniques; D003030:Coagulase / Q000235:genetics; D024881:Drug Resistance, Bacterial / Q000235:genetics; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D018805:Sepsis / Q000382:microbiology; D012867:Skin / Q000382:microbiology; D013203:Staphylococcal Infections / Q000382:microbiology; D013210:Staphylococcus / Q000145:classification* / Q000187:drug effects* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D003030:Coagulase