title: Predictors of elective pregnancy termination among women diagnosed with HIV during pregnancy in two regions of China, 2004-2010.
abstract: OBJECTIVE
  To document the rates of abortion among women diagnosed with HIV during pregnancy in two regions of China, and to investigate the sociodemographic factors associated with women's decisions to terminate their pregnancy.
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  Three central Chinese provinces (Hubei, Hebei and Shanxi) and Yining, Xinjiang.
  
  
  METHODS
  Women diagnosed with HIV during pregnancy, 2004-2010.
  
  
  METHODS
  Of 798 HIV-infected pregnant women identified through routine screening of pregnant women via antenatal care between 2004 and 2010, 499 women made decisions about the outcome of pregnancy. Chi-squared test was used to describe the characteristics of women who chose to terminate their pregnancies. Logistic regression models were used to identify potential predictors for pregnancy outcome for one cohort of women in central China and a second cohort of women in Yining, Xinjiang.
  
  
  METHODS
  Pregnancy outcome, trends of elective pregnancy termination.
  
  
  RESULTS
  In the central China cohort, 76 of 161 pregnancies (47.2%) were terminated. In Yining, the proportion was significantly less, at only 61 of 338 (18.0%). Factors associated with pregnancy termination included unmarried marital status, already having one or more children and earlier trimester of pregnancy at the time of diagnosis.
  
  
  CONCLUSIONS
  The rate of pregnancy termination in these cohorts of HIV-infected women appears to be higher than the rate in the general population of women in China. More work needs to be carried out to decrease the social stigma related to HIV and to convey clear messages about the effectiveness of prevention of mother to child transmission to women and their families. The significantly lower rate of pregnancy termination in Yining relative to central China is probably a result of the cultural and religious reservations towards pregnancy termination. Healthcare workers providing services to HIV-infected pregnant women need to be sensitive to cultural factors influencing women's decisions with regard to pregnancy termination.
authors.affiliation: Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
authors.forename: K
authors.initials: K
authors.lastname: Liang
authors.forename: K
authors.initials: K
authors.lastname: Meyers
authors.forename: W
authors.initials: W
authors.lastname: Zeng
authors.forename: X
authors.initials: X
authors.lastname: Gui
mesh_terms: D000028:Abortion, Induced / Q000706:statistics & numerical data* / Q000639:trends; D000328:Adult; D016009:Chi-Square Distribution; D002681:China; D003657:Decision Making; D005006:Ethnicity / Q000706:statistics & numerical data; D005191:Family Characteristics; D005260:Female; D005865:Gestational Age; D015658:HIV Infections / Q000175:diagnosis*; D006801:Humans; D016015:Logistic Models; D017533:Marital Status / Q000706:statistics & numerical data; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000821:virology; D011446:Prospective Studies; D012307:Risk Factors
keywords: Abortion; China; HIV; pregnancy; pregnancy termination