title: Medication-taking self-efficacy and medication adherence among HIV-infected cocaine users.
abstract: This prospective, observational study tested the ability of self-efficacy for taking antiretroviral medications to predict medication adherence among current and former cocaine and heroin users. Electronic monitors to record bottle openings and self-report measures of medication adherence were used. The sample included 99 men and women who were interviewed at 4-week intervals for 6 months. Mixed effects regression models to test the relationship of substance use and self-efficacy for medication-taking with percent of self-report adherence, dose adherence, number of days adherent, and adherence to medication schedule at each study visit showed that medication-taking self-efficacy was significantly related to all measures of adherence except schedule adherence. Findings also showed that electronically monitored adherence measures declined over the study period whereas self-report adherence did not. Findings suggest that self-efficacy can have a sustained effect on adherence to doses but may not be an influential predictor of adherence to their correct timing.
authors.affiliation: Nell Hodgson Woodruff School of Nursing, Emory University Atlanta, Georgia, USA.
authors.forename: Drenna
authors.initials: D
authors.lastname: Waldrop-Valverde
authors.forename: Chuanhui
authors.initials: C
authors.lastname: Dong
authors.forename: Raymond L
authors.initials: RL
authors.lastname: Ownby
mesh_terms: D000293:Adolescent; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D019970:Cocaine-Related Disorders / Q000150:complications* / Q000453:epidemiology; D004334:Drug Administration Schedule; D005260:Female; D005431:Florida / Q000453:epidemiology; D005500:Follow-Up Studies; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D006556:Heroin Dependence / Q000150:complications / Q000453:epidemiology; D006801:Humans; D008297:Male; D055118:Medication Adherence / Q000523:psychology; D008875:Middle Aged; D012044:Regression Analysis; D020377:Self Efficacy; D057566:Self Report; D012959:Socioeconomic Factors; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000453:epidemiology; D013997:Time Factors; D055815:Young Adult; D016903:Drug Monitoring
chemical_list: D019380:Anti-HIV Agents