title: Premature ejaculation results in female sexual distress: standardization and validation of a new diagnostic tool for sexual distress.
abstract: OBJECTIVE
  We measured premature ejaculation related female sexual distress using a new diagnostic tool, the Female Sexual Distress Scale-Revised-Premature Ejaculation questionnaire.
  
  
  METHODS
  In this large-scale, Internet based population study we evaluated 2,109 women in a stable relationship during the last 6 months. The 1,361 women in the premature ejaculation group had no female sexual disorder but the partner had premature ejaculation alone. The 748 controls had no female sexual disorder and a partner without premature ejaculation. We determined questionnaire content and discriminant validity, internal consistency and test-retest reliability. Multivariate logistic regression with propensity score reweighting was done to determine the clinical impact of demographics on the perception of sexual distress.
  
  
  RESULTS
  The questionnaire was well understood. Internal consistency was greater than 0.90 and 0.84 in the premature ejaculation and control groups, respectively. Test-retest reliability was 0.82 (95% CI 0.72-0.87) and 0.85 (95% CI 0.79-0.92) in the premature ejaculation and control groups, respectively. The questionnaire had a high AUC of 0.90 (95% CI 0.89-0.91). The new cutoff score of 12 or greater had 79.1% sensitivity (95% CI 73.8-82.5), 99.5% specificity (95% CI 98.0-100.0), 99.3% positive predictive value (95% CI 98.7-100.0) and 67.9% negative predictive value (95% CI 64.2-73.2). Median questionnaire scores were significantly higher in the premature ejaculation group than in controls (20, 95% CI 19-21 vs 6, 95% CI 6-7, p <0.0001). Logistic regression adjusted and unadjusted by propensity score indicated that women in the premature ejaculation group had a 7.12 (95% CI 5.98-10.14, p <0.0001) to 9.83 (95% CI 7.94-12.15) greater probability of sexual distress than controls.
  
  
  CONCLUSIONS
  The Female Sexual Distress Scale-Revised-Premature Ejaculation questionnaire fulfills psychometric requirements for measuring sexual distress related to partner sexual dysfunction.
authors.affiliation: School of Sexology, Department of Clinical, Applied and Biotechnological Sciences, University of L'Aquila, L'Aquila, Italy.
authors.forename: Erika
authors.initials: E
authors.lastname: Limoncin
authors.forename: Marco
authors.initials: M
authors.lastname: Tomassetti
authors.forename: Giovanni Luca
authors.initials: GL
authors.lastname: Gravina
authors.forename: Giacomo
authors.initials: G
authors.lastname: Ciocca
authors.forename: Eleonora
authors.initials: E
authors.lastname: Carosa
authors.forename: Stefania
authors.initials: S
authors.lastname: Di Sante
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Gentile
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Mirone
authors.forename: Francesco
authors.initials: F
authors.lastname: Montorsi
authors.forename: Andrea
authors.initials: A
authors.lastname: Lenzi
authors.forename: Emmanuele A
authors.initials: EA
authors.lastname: Jannini
mesh_terms: D000293:Adolescent; D000328:Adult; D004542:Ejaculation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012735:Sexual Dysfunction, Physiological; D020018:Sexual Dysfunctions, Psychological / Q000175:diagnosis* / Q000209:etiology*; D012747:Sexual Partners; D013315:Stress, Psychological / Q000175:diagnosis* / Q000209:etiology*; D011795:Surveys and Questionnaires; D055815:Young Adult