title: [Influence of pineal hormone melatonin on behavioral disturbances and neurological status of animals after hemorrhagic stroke].
abstract: Experimental hemorrhagic stroke causes behavior and locomotor activity with memory impairment and neurological disturbances in rats. These shifts are weaker in the evening hours than after morning testing. The repeated administration of the pineal gland hormone melatonin (melaxen) during one week significantly decreases behavior and neurological deficits as well as pathomorphological signs in the lesion focus. The normalizing effect of the hormone is more distinct in the evening.
authors.forename: E B
authors.initials: EB
authors.lastname: Arushanian
authors.forename: S S
authors.initials: SS
authors.lastname: Naumov
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D002940:Circadian Rhythm / Q000187:drug effects / Q000502:physiology; D020300:Intracranial Hemorrhages / Q000150:complications*; D008550:Melatonin / Q000008:administration & dosage* / Q000378:metabolism; D018696:Neuroprotective Agents / Q000008:administration & dosage*; D009483:Neuropsychological Tests; D010870:Pineal Gland / Q000378:metabolism; D051381:Rats; D020521:Stroke / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology
chemical_list: D018696:Neuroprotective Agents; D008550:Melatonin