title: [A simple kinetic model of contraction of striated muscle: full activation at full filament overlap in sarcomeres].
abstract: A simple kinetic model of muscle contraction is suggested. The rates of cross-bridge transitions from one kinetic state to another are supposed to depend on the averaged (over ensemble of actin-bound bridges) strain. With a proper set of the strain-dependent rates the model fits well a broad set of experimental data. Due to its simplicity, the relation between strain and stress is described by a set of ordinary differential equations; the model can be used for simulation of complex 3D muscle contraction.
authors.forename: F A
authors.initials: FA
authors.lastname: Sëmin
authors.forename: A K
authors.initials: AK
authors.lastname: Tsaturian
mesh_terms: D000199:Actins / Q000502:physiology; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D001696:Biomechanical Phenomena; D003198:Computer Simulation; D003599:Cytoskeleton / Q000502:physiology*; D007700:Kinetics; D008954:Models, Biological; D009119:Muscle Contraction / Q000502:physiology*; D009218:Myosins / Q000502:physiology; D011898:Ranidae; D012518:Sarcomeres / Q000502:physiology*
chemical_list: D000199:Actins; D000255:Adenosine Triphosphate; D009218:Myosins