title: Azide-alkyne Huisgen [3+2] cycloaddition using CuO nanoparticles.
abstract: Recent developments in the synthesis of CuO nanoparticles (NPs) and their application to the [3+2] cycloaddition of azides with terminal alkynes are reviewed. With respect to the importance of click chemistry, CuO hollow NPs, CuO hollow NPs on acetylene black, water-soluble double-hydrophilic block copolymer (DHBC) nanoreactors and ZnO&#8211;CuO hybrid NPs were synthesized. Non-conventional energy sources such as microwaves and ultrasound were also applied to these click reactions, and good catalytic activity with high regioselectivity was observed. CuO hollow NPs on acetylene black can be recycled nine times without any loss of activity, and water-soluble DHBC nanoreactors have been developed for an environmentally friendly process.
authors.affiliation: Department of Chemistry, Chemistry Institute for Functional Materials, Pusan National University, Busan 609-735, Korea. chemistry@pusan.ac.kr
authors.forename: Hyunje
authors.initials: H
authors.lastname: Woo
authors.forename: Hyuntae
authors.initials: H
authors.lastname: Kang
authors.forename: Aram
authors.initials: A
authors.lastname: Kim
authors.forename: Seongwan
authors.initials: S
authors.lastname: Jang
authors.forename: Ji Chan
authors.initials: JC
authors.lastname: Park
authors.forename: Sungkyun
authors.initials: S
authors.lastname: Park
authors.forename: Byeong-Su
authors.initials: BS
authors.lastname: Kim
authors.forename: Hyunjoon
authors.initials: H
authors.lastname: Song
authors.forename: Kang Hyun
authors.initials: KH
authors.lastname: Park
mesh_terms: D000114:Acetylene / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry*; D061565:Cycloaddition Reaction; D055772:Green Chemistry Technology; D006571:Heterocyclic Compounds / Q000138:chemical synthesis; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D011205:Povidone / Q000737:chemistry; D053260:Soot / Q000737:chemistry; D013816:Thermodynamics; D015034:Zinc Oxide / Q000737:chemistry
chemical_list: D000480:Alkynes; D001386:Azides; D006571:Heterocyclic Compounds; D053260:Soot; D003300:Copper; D011205:Povidone; D000114:Acetylene; D015034:Zinc Oxide; C030973:cupric oxide