title: [Obstetrical and gynecological relevance of inflammatory bowel disease].
abstract: BACKGROUND
  Inflammatory bowel disease may show a life long persistence, while female fertility is time-limited.
  
  
  OBJECTIVE
  The aim of the authors was to obtain more knowledge about the obstetrical-gynecological aspects of this disorder.
  
  
  METHODS
  The authors evaluated 100 patients with inflammatory bowel disease and 100 healthy women with a self-composed questionnaire.
  
  
  RESULTS
  Menarche occurred significantly earlier in patients than in controls (p = 0,03). Either the activity of the disease, or the therapy itself may initiate irregularities in the menstrual cycle. Patients used contraceptives less frequently than controls (p = 0,002), and the time from family-planning to conception was longer in patients. Symptoms of bowel disease during pregnancy were not as severe as before and after pregnancy (p<0,001). Excess weight had a beneficial effect on symptoms during pregnancy (p = 0,042) and on the frequency of complications. Preterm birth and low birth weight were more frequent in newborns of patients (p = 0,019).
  
  
  CONCLUSIONS
  Pregnancy has positive effect on the symptoms of inflammatory bowel disease in case gestation occurs in a stable period of the inflammatory bowel disease.
authors.affiliation: Semmelweis Egyetem, Általános Orvostudományi Kar I. Sebészeti Klinika, Budapest. kalmanj87@gmail.com
authors.forename: Judit
authors.initials: J
authors.lastname: Kálmán
authors.forename: Judit
authors.initials: J
authors.lastname: Bajor
authors.forename: János
authors.initials: J
authors.lastname: Gáll
authors.forename: László
authors.initials: L
authors.lastname: Harsányi
authors.forename: Henrik Csaba
authors.initials: HC
authors.lastname: Horváth
authors.forename: Olga
authors.initials: O
authors.lastname: Kerékgyártó
authors.forename: Adám
authors.initials: A
authors.lastname: László
authors.forename: János
authors.initials: J
authors.lastname: Novák
authors.forename: Agnes
authors.initials: A
authors.lastname: Salamon
authors.forename: Judit
authors.initials: J
authors.lastname: Wacha
mesh_terms: D000328:Adult; D017668:Age of Onset; D000368:Aged; D001942:Breast Feeding / Q000706:statistics & numerical data; D016022:Case-Control Studies; D003270:Contraceptive Agents / Q000627:therapeutic use; D005260:Female; D005306:Fertilization; D006176:Gynecology; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D015212:Inflammatory Bowel Diseases / Q000150:complications* / Q000628:therapy; D008572:Menarche; D008599:Menstruation Disturbances / Q000453:epidemiology* / Q000209:etiology*; D008875:Middle Aged; D009774:Obstetrics; D050177:Overweight; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000209:etiology*; D047928:Premature Birth / Q000453:epidemiology* / Q000209:etiology; D011795:Surveys and Questionnaires; D013997:Time Factors
chemical_list: D003270:Contraceptive Agents