title: New iridoid glycoside from Gratiola officinalis.
abstract: A new iridoid glycoside, 1β,6β-di-O-trans-cinnamoyl-9-O-β-D-glucopyranosyl-3-iridene-5β-ol (1), along with four known compounds loliolide (2), β-sitosterol-3-O-β-D-glucopyranoside (3), betulinic acid (4), and β-amyrin (5), was isolated from the aerial parts of Gratiola officinalis L. The structure of the new compound was deduced on the basis of 1D ¹H and ¹³C NMR and 2D HMQC, HMBC, and COSY experiments, and mass spectrometric techniques (EI-MS and HR-EI-MS). The relative configuration of 1 was assigned by comparative analysis of the NMR spectral data with known analogs, together with NOESY experiments.
authors.affiliation: HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan. malikhejric@gmail.com
authors.forename: Liaqat
authors.initials: L
authors.lastname: Ali
authors.forename: Tania Shamim
authors.initials: TS
authors.lastname: Rizvi
authors.forename: Manzoor
authors.initials: M
authors.lastname: Ahmad
authors.forename: Farzana
authors.initials: F
authors.lastname: Shaheen
mesh_terms: D005960:Glucosides; D057889:Iridoid Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010154:Pakistan; D028083:Scrophulariaceae / Q000737:chemistry*; D012855:Sitosterols
chemical_list: C578171:1beta,6beta-di-O-trans-cinnamoyl-9-O-beta-D-glucopyranosyl-3-iridene-5beta-ol; D005960:Glucosides; D057889:Iridoid Glycosides; D012855:Sitosterols; C472604:sitosterol-3-O-glucopyranoside