title: Atypical 'benign behaviour' of eyelid sebaceous carcinoma.
abstract: Eyelid sebaceous carcinoma is a rare tumour with slow growth and it is one of the most aggressive malignancies of the eyelid. Death rate can reach 6%. The diagnosis is often delayed because it is confused with other periocular lesions. The authors describe a case with atypical presentation, regarding rapid growth rate and exophytic aspect. Female, 78 years, presenting lower eyelid tumour with 4 months of evolution. Ophthalmological examination showed a tarsal exophytic tumour (22 mm), non-adherent to bulbar conjunctiva. She was medicated topically for 3 months, with the diagnosis of chalazio. Total excision was performed for histological diagnosis. After diagnosis of sebaceous carcinoma with specific immunohistochemical markers, and without free tumour surgical limits, a second surgery was performed with a pentagon entire thickness excision. Being a rare tumour but with a considerable morbidity and mortality; early diagnosis and treatment is essential for a good prognosis and preservation of visual function.
authors.affiliation: Department of Ophthalmology, Hospital Prof. Dr. Fernando Fonseca, Lisboa, Portugal. samuel.oft@gmail.com
authors.forename: Samuel
authors.initials: S
authors.lastname: Alves
authors.forename: Filipe
authors.initials: F
authors.lastname: Silva
authors.forename: Mara
authors.initials: M
authors.lastname: Ferreira
authors.forename: João
authors.initials: J
authors.lastname: Cabral
mesh_terms: D018266:Adenocarcinoma, Sebaceous / Q000473:pathology / Q000601:surgery; D000368:Aged; D003228:Conjunctiva; D005142:Eyelid Neoplasms / Q000473:pathology / Q000601:surgery; D005143:Eyelids / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D012626:Sebaceous Gland Neoplasms / Q000473:pathology / Q000601:surgery