title: Tunable carbon nanotube/protein core-shell nanoparticles with NIR- and enzymatic-responsive cytotoxicity.
abstract: A unique procedure is developed to capture carbon nanotubes into closed virus-like protein cages with a controllable shell. The cross-linked shell varies in thickness within ≈10(0) -10(2)  nm, and can be entirely removed by enzyme degradation. The cytotoxicity is entirely suppressed, but can be promoted again by enzymes and near-infrared light. These hybrids can be decorated with functional inorganic nanoparticles or processed into nanocomposites.
authors.affiliation: ETH Zurich, Department of Health Science & Technology, Schmelzbergstrasse 9, Zürich, Switzerland.
authors.forename: Chaoxu
authors.initials: C
authors.lastname: Li
authors.forename: Sreenath
authors.initials: S
authors.lastname: Bolisetty
authors.forename: Krishna
authors.initials: K
authors.lastname: Chaitanya
authors.forename: Jozef
authors.initials: J
authors.lastname: Adamcik
authors.forename: Raffaele
authors.initials: R
authors.lastname: Mezzenga
mesh_terms: D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007259:Infrared Rays; D007782:Lactoglobulins / Q000737:chemistry / Q000378:metabolism; D053758:Nanoparticles / Q000737:chemistry* / Q000633:toxicity; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000633:toxicity; D011506:Proteins / Q000737:chemistry / Q000378:metabolism*; D013696:Temperature
chemical_list: D007782:Lactoglobulins; D037742:Nanotubes, Carbon; D011506:Proteins