title: Ghost cell odontogenic carcinoma arising from calcifying cystic odontogenic tumor: a case report.
abstract: Ghost cell odontogenic carcinoma (GCOC) is an exceptionally rare and malignant odontogenic tumor with aggressive growth characteristics. We describe a case of GCOC which was considerably derived from a previously resected calcifying cystic odontogenic tumor (CCOT). Cellular atypia, mitotic activity, Ki-67 labeling index and matrix metalloprotease-9 positive expression rate were all increased in the currently resected specimen compared to the initial one. This is a rare case of malignant transformation of CCOT to GCOC with respect to its histopathological and immunohistochemical findings.
authors.affiliation: Department of Pathology, West China Hospital of Stomatology, Sichuan University, Sichuan, China.
authors.forename: Zhi-Yu
authors.initials: ZY
authors.lastname: Zhu
authors.forename: Zhi-Gang
authors.initials: ZG
authors.lastname: Chu
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
authors.forename: Wei-Ping
authors.initials: WP
authors.lastname: Zhang
authors.forename: Di
authors.initials: D
authors.lastname: Lv
authors.forename: Ning
authors.initials: N
authors.lastname: Geng
authors.forename: Ming-Zhong
authors.initials: MZ
authors.lastname: Yang
keywords: Calcifying cystic odontogenic tumor; Ghost cell odontogenic carcinoma