title: Individual differences in the proneness to have flow experiences are linked to dopamine D2-receptor availability in the dorsal striatum.
abstract: Flow is a subjective experience of high but effortless attention, enjoyment, and low self-awareness that can occur during the active performance of challenging tasks. The dispositional proneness to experience flow is associated with personality traits that are known to be influenced by dopaminergic neural systems. Here, for the first time, we investigated relations between flow proneness and dopaminergic function. Specifically, we tested the hypothesis that the availability of dopamine D2-receptors in the striatum is positively associated with flow proneness. Striatal D2-receptor availability was measured in a sample of 25 healthy adults using positron emission tomography and [(11)C]raclopride. Flow proneness was measured using the Swedish Flow Proneness Questionnaire. As hypothesized, there was a significant correlation (r=.41) between striatal D2-receptor availability and flow proneness. An exploratory analysis of striatal subregions showed that the relation was mainly driven by the dorsal striatum, with a significantly higher correlation in the putamen than in the ventral striatum. The findings constitute the first demonstration of an association between flow proneness and dopaminergic function. We suggest that the proneness to experience flow is related to personality dimensions that are under dopaminergic control and characterized by low impulsiveness, stable emotion, and positive affect.
authors.affiliation: Department of Neuroscience, Karolinska Institutet, SE-171 77 Stockholm, Sweden. orjan.demanzano@ki.se
authors.forename: Örjan
authors.initials: Ö
authors.lastname: de Manzano
authors.forename: Simon
authors.initials: S
authors.lastname: Cervenka
authors.forename: Aurelija
authors.initials: A
authors.lastname: Jucaite
authors.forename: Oscar
authors.initials: O
authors.lastname: Hellenäs
authors.forename: Lars
authors.initials: L
authors.lastname: Farde
authors.forename: Fredrik
authors.initials: F
authors.lastname: Ullén
mesh_terms: D000328:Adult; D000368:Aged; D001076:Aptitude / Q000502:physiology*; D001288:Attention / Q000502:physiology*; D001364:Awareness; D003342:Corpus Striatum / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009042:Motivation / Q000502:physiology*; D020891:Raclopride / Q000493:pharmacokinetics*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D017448:Receptors, Dopamine D2 / Q000378:metabolism*; D014018:Tissue Distribution
chemical_list: C581293:DRD2 protein, human; D019275:Radiopharmaceuticals; D017448:Receptors, Dopamine D2; D020891:Raclopride