title: Hematological complications of neonatal lupus: case report and review of the literature.
abstract: Neonatal thrombocytopenia is a common clinical problem and may be a result of maternal and/or fetal conditions. We present a young patient with thrombocytopenia as a result of neonatal lupus, a passively acquired autoimmune disease. The diagnosis was suspected on the basis of the presence of a facial rash. This case highlights the characteristic eruption of neonatal lupus and an underappreciated cause of neonatal thrombocytopenia for the pediatric hematologist. We also review the hematological complications of neonatal lupus.
authors.affiliation: *Division of Pediatric Oncology, Children's National Medical Center, Center for Blood and Cancer Disorders of Northern Virginia, Fairfax, VA †Division of Hematology, Children's National Medical Center ‡Pasquerilla Healthcare Center, Georgetown University Hospital, Washington, DC.
authors.forename: Mwe Mwe
authors.initials: MM
authors.lastname: Chao
authors.forename: Lori
authors.initials: L
authors.lastname: Luchtman-Jones
authors.forename: Robert A
authors.initials: RA
authors.lastname: Silverman
mesh_terms: D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis* / Q000503:physiopathology; D008180:Lupus Erythematosus, Systemic / Q000151:congenital* / Q000175:diagnosis / Q000503:physiopathology; D011247:Pregnancy; D011248:Pregnancy Complications; D012859:Sjogren's Syndrome; D013921:Thrombocytopenia / Q000209:etiology*