title: [Billateral pleural effusion as first manifestation of multiple myeloma].
abstract: Multiple myeloma is clonal malignancy of plasma cells with overproduction of monoclonal antibodies and destruction of bones. Hypercalcemia, anemia and renal disfunction are common manifestations of the disease. Billateral pleural effusion is rare multiple myeloma presentation with unfavorable prognosis so it is important to recognizze it for better diagnostic and therapy approach. 59-year old woman was admitted to Hematology Department with history of severe caugh, dyspnea and left chest pain. Physical examination and chest X-ray showed billateral pleural effusion while cytologic examination of pleural aspirate found plasma cells. Bone marrow examination and skeleton X-ray confirmed diagnosis of multiple myeloma. Serum and urine immunoelectrophoresis detected lambda Bence Jones protein. This case is rare manifestation of multiple myeloma.
authors.affiliation: Merkur University Hospital, Department of Internal Medicine, Division of Hematology, Zagreb, Croatia. delfa.radic.kristo@zg.t-com.hr
authors.forename: Delfa
authors.initials: D
authors.lastname: Radić-Kristo
authors.forename: Slobodanka Ostojić
authors.initials: SO
authors.lastname: Kolonić
authors.forename: Ika
authors.initials: I
authors.lastname: Kardum-Skelin
authors.forename: Inga Mandac
authors.initials: IM
authors.lastname: Rogulj
authors.forename: Radovan
authors.initials: R
authors.lastname: Vrhovac
authors.forename: Ana
authors.initials: A
authors.lastname: Planinc-Peraica
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000175:diagnosis*; D016066:Pleural Effusion, Malignant / Q000209:etiology*