title: Antifungal susceptibility to amphotericin B, fluconazole, voriconazole, and flucytosine in Candida bloodstream isolates from 15 tertiary hospitals in Korea.
abstract: The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioMérieux, France). Overall susceptibility rates were 98.1%, 95.9%, 99.1%, and 97.3% for amphotericin B, fluconazole, voriconazole, and flucytosine, respectively. The results show that the rates of resistance to 4 antifungal drugs remain low among Candida bloodstream isolates in Korea.
authors.affiliation: Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
authors.forename: Sook-In
authors.initials: SI
authors.lastname: Jung
authors.forename: Jong Hee
authors.initials: JH
authors.lastname: Shin
authors.forename: Hyun-Jung
authors.initials: HJ
authors.lastname: Choi
authors.forename: Min-Young
authors.initials: MY
authors.lastname: Ju
authors.forename: Soo-Hyun
authors.initials: SH
authors.lastname: Kim
authors.forename: Wee Gyo
authors.initials: WG
authors.lastname: Lee
authors.forename: Yeon-Joon
authors.initials: YJ
authors.lastname: Park
authors.forename: Kyungwon
authors.initials: K
authors.lastname: Lee
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects* / Q000302:isolation & purification; D002177:Candidiasis / Q000097:blood / Q000382:microbiology; D015725:Fluconazole / Q000494:pharmacology*; D005437:Flucytosine / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D011743:Pyrimidines / Q000494:pharmacology*; D056910:Republic of Korea; D062606:Tertiary Care Centers; D014230:Triazoles / Q000494:pharmacology*; D065819:Voriconazole
chemical_list: D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D000666:Amphotericin B; D015725:Fluconazole; D005437:Flucytosine; D065819:Voriconazole
keywords: Amphotericin B; Candida; Fluconazole; Flucytosine; Voriconazole