title: Application of Tb(4)O(7) nanoparticles for lasalocid and salicylate determination in food analysis.
abstract: The usefulness of Tb(4)O(7) nanoparticles (NPs) as analytical reagents using sensitized luminescence as a detection system is described for the first time, and the results obtained are compared with those obtained using Tb(III) ions. Two drugs used in veterinary practice, namely, lasalocid (LAS) and salicylate (SAL), have been chosen as model analytes to carry out this study. The experimental conditions for these systems have been optimized, and their analytical features were obtained. The detection limits obtained for LAS and SAL using Tb(4)O(7) NPs were 1.0 and 4.0 ng mL(-1), respectively, which were comparable to those obtained using Tb(III) ions: 1.8 and 1.0 ng mL(-1), respectively. However, precision data, with relative standard deviation values in the range 2.3-3.8% using the NPs and 3.5-6.5% using Tb(III) ions, were slightly better for LAS with Tb(4)O(7) NPs. The practical analytical usefulness of Tb(4)O(7) NPs as luminescent reagents has been shown by performing the determination of LAS in tap water, feed premix, and egg samples, obtaining recoveries in the range of 80.0-105.0%.
authors.affiliation: Department of Analytical Chemistry, Research Institute of Fine Chemistry and Nanochemistry, Campus of Rabanales, Marie Curie Building (Annex), University of Cordoba, 14071-Cordoba, Spain.
authors.forename: María Luisa
authors.initials: ML
authors.lastname: Castillo-García
authors.forename: María Paz
authors.initials: MP
authors.lastname: Aguilar-Caballos
authors.forename: Agustina
authors.initials: A
authors.lastname: Gómez-Hens
mesh_terms: D000821:Animal Feed / Q000032:analysis; D003049:Coccidiostats / Q000032:analysis; D004531:Eggs / Q000032:analysis; D005504:Food Analysis / Q000379:methods*; D007202:Indicators and Reagents; D007832:Lasalocid / Q000032:analysis*; D008163:Luminescent Measurements; D053758:Nanoparticles; D010087:Oxides / Q000737:chemistry; D020156:Salicylic Acid / Q000032:analysis*; D013725:Terbium / Q000737:chemistry*; D019155:Veterinary Drugs / Q000032:analysis*
chemical_list: D003049:Coccidiostats; D007202:Indicators and Reagents; D010087:Oxides; D019155:Veterinary Drugs; D013725:Terbium; D020156:Salicylic Acid; D007832:Lasalocid