title: No association between TGF-β1 polymorphisms and radiation-induced lung toxicity in a European cohort of lung cancer patients.
abstract: This study aimed at validating the previously published association between TGF-β1 single nucleotide polymorphisms and a reduced risk for radiation-induced lung toxicity. We were not able to confirm the reported association, neither using maximum dyspnea score nor after correction for baseline dyspnea score.
authors.affiliation: Maastricht University, The Netherlands.
authors.forename: An M
authors.initials: AM
authors.lastname: Voets
authors.forename: Cary
authors.initials: C
authors.lastname: Oberije
authors.forename: Robin B
authors.initials: RB
authors.lastname: Struijk
authors.forename: Bart
authors.initials: B
authors.lastname: Reymen
authors.forename: Kim
authors.initials: K
authors.lastname: De Ruyck
authors.forename: Hubert
authors.initials: H
authors.lastname: Thierens
authors.forename: Katrien
authors.initials: K
authors.lastname: Vandecasteele
authors.forename: Wilfried
authors.initials: W
authors.lastname: De Neve
authors.forename: Ruud
authors.initials: R
authors.lastname: Houben
authors.forename: Dirk
authors.initials: D
authors.lastname: De Ruysscher
authors.forename: Hubert J M
authors.initials: HJ
authors.lastname: Smeets
authors.forename: Philippe
authors.initials: P
authors.lastname: Lambin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000235:genetics* / Q000473:pathology / Q000532:radiotherapy; D015331:Cohort Studies; D004417:Dyspnea / Q000209:etiology; D005060:Europe; D005260:Female; D005500:Follow-Up Studies; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D008175:Lung Neoplasms / Q000235:genetics* / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D020641:Polymorphism, Single Nucleotide; D017564:Radiation Pneumonitis / Q000235:genetics; D011879:Radiotherapy Dosage; D012307:Risk Factors; D055752:Small Cell Lung Carcinoma / Q000235:genetics* / Q000473:pathology / Q000532:radiotherapy; D053773:Transforming Growth Factor beta1 / Q000235:genetics*
chemical_list: D053773:Transforming Growth Factor beta1