title: Bronchial asthma developing after 15 years of immunosuppressive treatment following renal transplantation.
abstract: A 42-year-old woman who underwent renal transplantation from her mother at the age of 26 due to IgA nephropathy had since been treated with immunosuppressive agents, including prednisolone (PSL), azathioprine (AZA) and cyclosporine (CsA). The patient had remained clinically stable for 15 years. However, in the middle of May 2010, she developed bronchial asthma for the first time after performing house-cleaning activities and was treated with corticosteroids and antiasthmatic agents. The use of immunosuppressive agents as a treatment for severe bronchial asthma might have been related to the manifestation of bronchial asthma in this case.
authors.affiliation: Department of Respiratory Medicine, Tokai University Hachioji Hospital, Tokai University School of Medicine, Japan. watanabe.hidehiro@hachioji-hosp.tokai.ac.jp
authors.forename: Hidehiro
authors.initials: H
authors.lastname: Watanabe
authors.forename: Tomonori
authors.initials: T
authors.lastname: Uruma
authors.forename: Tokuro
authors.initials: T
authors.lastname: Tsunoda
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishii
authors.forename: Gen
authors.initials: G
authors.lastname: Tazaki
authors.forename: Tetsuri
authors.initials: T
authors.lastname: Kondo
mesh_terms: D000328:Adult; D001249:Asthma / Q000000981:diagnostic imaging / Q000209:etiology* / Q000276:immunology; D001379:Azathioprine / Q000009:adverse effects; D016572:Cyclosporine / Q000009:adverse effects; D005260:Female; D005922:Glomerulonephritis, IGA / Q000150:complications / Q000188:drug therapy / Q000601:surgery; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation / Q000009:adverse effects*; D011239:Prednisolone / Q000009:adverse effects; D011859:Radiography; D013997:Time Factors
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine; D011239:Prednisolone; D001379:Azathioprine