title: Desmopressin-induced posterior reversible encephalopathy syndrome.
abstract: We herein report the case of a patient who presented with an acute decrease of visual acuity, hypertension, focal seizures and transient mental dysfunction while undergoing desmopressin treatment. Neuroimaging revealed bilateral occipital-parietal lesions that presented with vasogenic edema. After controlling the hypertension and discontinuing the desmopressin treatment, the patient's condition improved. A follow-up imaging examination performed six months later showed complete resolution of the lesions. It is important to recognize posterior reversible encephalopathy syndrome (PRES) as a rare and serious complication of desmopressin administration. Both the blood pressure and water electrolyte balance should be carefully monitored in patients receiving desmopressin therapy.
authors.affiliation: Brain Medical Center, First Affiliated Hospital, Zhejiang University School of Medicine, China.
authors.forename: Ruili
authors.initials: R
authors.lastname: Wei
authors.forename: Lu
authors.initials: L
authors.lastname: Jin
authors.forename: Jianhe
authors.initials: J
authors.lastname: Huang
authors.forename: Benyan
authors.initials: B
authors.lastname: Luo
mesh_terms: D000328:Adult; D050034:Antidiuretic Agents / Q000009:adverse effects; D001794:Blood Pressure / Q000187:drug effects; D003894:Deamino Arginine Vasopressin / Q000009:adverse effects*; D020790:Diabetes Insipidus, Neurogenic / Q000188:drug therapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D054038:Posterior Leukoencephalopathy Syndrome / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D014057:Tomography, X-Ray Computed; D014882:Water-Electrolyte Balance / Q000187:drug effects
chemical_list: D050034:Antidiuretic Agents; D003894:Deamino Arginine Vasopressin