title: Separation and preconcentration of 2,3,7,8-tetrachlorodibenzo-p-dioxin in blood samples by inclusion emulsion membranes and its determination by gas chromatography.
abstract: The nano-mediated preconcentration of 2,3,7,8-tetrachlorodibenzo-p-dioxin from blood samples was reported by inclusion-facilitated emulsion liquid membrane process. The novelty of this study was application of nano-baskets of calixarene and emulsion liquid membranes in selective and efficient preconcentration of 2,3,7,8-tetrachlorodibenzo-p-dioxin. For this aim, four derivatives of p-tert-calix[4]arene bearing different sulfonamide moieties were synthesized and their inclusion-extraction parameters were optimized including calixarenes' scaffold and concentration (3, 4 wt%), diluent type in membrane, phase and treat ratios (0.8 and 0.3), mixing speed (300 rpm), and initial solute concentrations (0.1-10 pg g(-1)). The extraction efficiency was determined by dioxin's concentration using gas chromatography equipped with electron capture detector and the results revealed that in optimized operating conditions, the preconcentration of 2,3,7,8-tetrachlorodibenzo-p-dioxin was improved and the limit of detection decreased.
authors.affiliation: Razi Chemistry Research Center (RCRC), Shahreza Branch, Islamic Azad University, Shahreza, Iran.
authors.forename: Bahram
authors.initials: B
authors.lastname: Mokhtari
authors.forename: Kobra
authors.initials: K
authors.lastname: Pourabdollah
mesh_terms: D053000:Analytic Sample Preparation Methods / Q000379:methods*; D047250:Calixarenes / Q000737:chemistry; D005591:Chemical Fractionation / Q000379:methods*; D002849:Chromatography, Gas; D004655:Emulsions; D004785:Environmental Pollutants / Q000097:blood* / Q000737:chemistry / Q000302:isolation & purification*; D006801:Humans; D008567:Membranes, Artificial; D000072317:Polychlorinated Dibenzodioxins / Q000097:blood* / Q000737:chemistry / Q000302:isolation & purification*; D013501:Surface-Active Agents / Q000737:chemistry
chemical_list: D004655:Emulsions; D004785:Environmental Pollutants; D008567:Membranes, Artificial; D000072317:Polychlorinated Dibenzodioxins; D013501:Surface-Active Agents; D047250:Calixarenes