title: Formal γ-alkynylation of ketones via Pd-catalyzed C-C cleavage.
abstract: A formal γ-alkynylation of ketones via Pd-catalyzed C-C bond-cleavage is presented. The method allows for the coupling of tert-cyclobutanols and bromoacetylenes, giving access to versatile alkynes that are beyond reach otherwise.
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), Av. Països Catalans 16, 43007, Tarragona, Spain.
authors.forename: Asraa
authors.initials: A
authors.lastname: Ziadi
authors.forename: Arkaitz
authors.initials: A
authors.lastname: Correa
authors.forename: Ruben
authors.initials: R
authors.lastname: Martin
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D061565:Cycloaddition Reaction; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry*; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D013696:Temperature
chemical_list: D000480:Alkynes; D001386:Azides; D007659:Ketones; D010165:Palladium; D002244:Carbon