title: Mechanism of action of 4-dialkylaminopyridines as secondary enhancers in enhanced chemiluminescence reaction.
abstract: Kinetic study of peroxidase-catalyzed oxidation of 3-(10'-phenothiazinyl)propane-1-sulfonate (SPTZ) by hydrogen peroxide demonstrated that the addition of 4-dialkylaminopyridines to a substrate solution significantly increased a rate of production of SPTZ cation radical and did not affect the rate of decomposition of this radical. These results explain the mechanism of action of 4-dialkylaminopyridines as secondary enhancers in enhanced chemiluminescence reaction used widely in analytical practice.
authors.affiliation: Department of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia. sakharovivan@gmail.com
authors.forename: Ivan Yu
authors.initials: IY
authors.lastname: Sakharov
authors.forename: Marina M
authors.initials: MM
authors.lastname: Vdovenko
mesh_terms: D017738:Alkanesulfonic Acids / Q000737:chemistry*; D000631:Aminopyridines / Q000737:chemistry*; D055162:Biocatalysis; D006861:Hydrogen Peroxide / Q000737:chemistry; D007700:Kinetics; D008163:Luminescent Measurements; D010084:Oxidation-Reduction; D010544:Peroxidases / Q000378:metabolism; D013843:Thiazines / Q000737:chemistry*
chemical_list: C543492:3-(10'-Phenothiazinyl)propane-1-sulfonate; D017738:Alkanesulfonic Acids; D000631:Aminopyridines; D013843:Thiazines; D006861:Hydrogen Peroxide; D010544:Peroxidases