title: Drug-induced interstitial lung disease in molecular targeted therapies: high-resolution CT findings.
abstract: Drug-induced lung injury (DLI) comprises a wide variety of pathologies, each with a unique imaging pattern, so there are no characteristic imaging findings to establish diagnosis. When DLI is suspected, evaluation must exclude progression of underlying disease, infection, and mimicking diseases. Correct diagnosis requires integration of clinical information and radiologic, laboratory, and pathological findings when available. We describe the radiologic findings of DLI, the roles of the findings in the management of patients with DLI, and the limitations of radiologic diagnosis.
authors.affiliation: Department of Diagnostic Radiology, Saitama International Medical Center, Saitama Medical University, Hidaka, Saitama, 350-1298, Japan. fmksakai@yahoo.co.jp
authors.forename: Fumikazu
authors.initials: F
authors.lastname: Sakai
authors.forename: Takeshi
authors.initials: T
authors.lastname: Johkoh
authors.forename: Masahiko
authors.initials: M
authors.lastname: Kusumoto
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Arakawa
authors.forename: Masahiro
authors.initials: M
authors.lastname: Takahashi
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced / Q000000981:diagnostic imaging* / Q000473:pathology; D058990:Molecular Targeted Therapy; D011658:Pulmonary Fibrosis / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed