title: Disease burden of immune thrombocytopenic purpura among adult patients: the analysis of Thailand healthcare databases 2010.
abstract: BACKGROUND
  Immune thrombocytopenic purpura (ITP) is not rare disease and it ispotentially fatal, particularly in patients with bleeding events which usually lead to hospitalization. Current data on the impact and disease burden of ITP in Thailand are lacking.
  
  
  OBJECTIVE
  To determine admission rate, mortality rate, hospital cost, length of hospital stay, co-morbidities, treatment and major bleeding events in patients with ITP.
  
  
  METHODS
  The authors analyzed the data of inpatients with a diagnosis of ITP according to ICD10 coded D69.3 which were retrieved from a nationwide health financing schemes in fiscal 2010. The data were analyzed by age groups, gender and health financing schemes.
  
  
  RESULTS
  The overall admission rate and mortality rate were 7.68 and 0.29 per 100,000 populations, respectively and increased with age. Women were predominant. Average hospital costs and hospital stays were 27,133 Baht and 6.7 days per admission, respectively and slightly higher among men than women. The most common co-morbidity was hypertension. Gastrointestinal hemorrhage was the most common bleeding event which was 21.5 per 1,000 admissions. Patients in the civil servant medical benefit scheme had the highest percentage of high cost treatment accessibility.
  
  
  CONCLUSIONS
  The admission rate, mortality rate and major bleeding events increased with age and was higher among women than men. Average hospital cost and length of hospital stay are higher in men than women. Common co-morbidities may be related to the treatment of ITP There are the differences in high-cost treatment accessibility between health insurance schemes.
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. nattiya@kku.ac.th
authors.forename: Nattiya
authors.initials: N
authors.lastname: Teawtrakul
authors.forename: Chittima
authors.initials: C
authors.lastname: Sirijerachai
authors.forename: Kanchana
authors.initials: K
authors.lastname: Chansung
authors.forename: Chinadol
authors.initials: C
authors.lastname: Wanitpongpun
authors.forename: Sumitr
authors.initials: S
authors.lastname: Sutra
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D005260:Female; D049670:History, 17th Century; D017721:Hospital Costs / Q000706:statistics & numerical data; D017052:Hospital Mortality; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D038801:International Classification of Diseases; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications / Q000453:epidemiology*; D012307:Risk Factors; D013785:Thailand / Q000453:epidemiology