title: Clival giant cell tumor presenting with isolated trigeminal nerve involvement.
abstract: Giant cell tumour (GCT) constitutes about 5 % of all skeletal tumors. They rarely occur in the skull. When involved, they preferentially involve the sphenoid or temporal bones. Skull-base GCTs generally present with multiple cranial nerves involvement, most commonly sixth followed by the third cranial nerve. We describe a case of clival GCT presenting with an isolated trigeminal nerve involvement in a 19-year-old man which was managed by surgery and adjuvant radiation. At 18 months of follow-up, the patient is clinically asymptomatic. Clival GCT should also be considered in the differential diagnosis of any isolated trigeminal nerve palsy. Adjuvant radiation has an important role to play in managing this tumour.
authors.affiliation: Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi, 110029, India. soumyajitroy8@gmail.com
authors.forename: Soumyajit
authors.initials: S
authors.lastname: Roy
authors.forename: Nikhil P
authors.initials: NP
authors.lastname: Joshi
authors.forename: Elanthenral
authors.initials: E
authors.lastname: Sigamani
authors.forename: Anita
authors.initials: A
authors.lastname: Malik
authors.forename: Meher C
authors.initials: MC
authors.lastname: Sharma
authors.forename: Bidhu K
authors.initials: BK
authors.lastname: Mohanti
authors.forename: Suresh C
authors.initials: SC
authors.lastname: Sharma
mesh_terms: D003388:Cranial Fossa, Posterior; D018212:Giant Cell Tumor of Bone / Q000150:complications*; D006801:Humans; D008297:Male; D019292:Skull Base Neoplasms / Q000150:complications*; D020433:Trigeminal Nerve Diseases / Q000209:etiology*; D055815:Young Adult