title: Does tranexamic acid reduce blood loss and blood transfusion requirement in knee arthroplasty?
abstract: Strong evidences which indicate that tranexamic acid reduces blood loss and blood transfusion requirement in patients who are scheduled for total knee arthroplasty are available. However, dose and method of administration, safety and side effects are still controversial issues. The effect of tranexamic acid on thromboembolic events and mortality is still unknown.
authors.affiliation: Department of Orthopedics and Traumatology, Medicine Faculty of Gazi University, 06500 Beşevler, Ankara, Turkey. satikmd@gmail.com
authors.forename: O Sahap
authors.initials: OS
authors.lastname: Atik
mesh_terms: D000933:Antifibrinolytic Agents / Q000008:administration & dosage*; D019645:Arthroplasty, Replacement, Knee; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001803:Blood Transfusion; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D014148:Tranexamic Acid / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D000933:Antifibrinolytic Agents; D014148:Tranexamic Acid