title: Oxygen treatment is effective in migraine with autonomic symptoms.
abstract: BACKGROUND
  While inhalation of high-flow 100% oxygen is highly effective in cluster headache, studies on its efficacy in migraine are sparse and controversial.
  
  
  METHODS
  We report the case of a 22-year-old patient with an eight-year history of strictly unilateral migraine without aura but cranial autonomic symptoms. She repeatedly responded completely to inhalation of high-flow pure oxygen within 15 min but suffered from recurrence of attacks within 30 min after discontinuation.
  
  
  CONCLUSIONS
  In line with experimental animal studies, this case suggests a clinically relevant efficacy of inhaled oxygen in patients with migraine with accompanying cranial autonomic symptoms.
authors.affiliation: Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Germany. t.juergens@uke.de
authors.forename: Tim P
authors.initials: TP
authors.lastname: Jürgens
authors.forename: Laura H
authors.initials: LH
authors.lastname: Schulte
authors.forename: Arne
authors.initials: A
authors.lastname: May
mesh_terms: D005260:Female; D006801:Humans; D020326:Migraine without Aura / Q000150:complications / Q000628:therapy*; D010100:Oxygen / Q000627:therapeutic use*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D010100:Oxygen