title: Application of near-infrared dyes for tumor imaging, photothermal, and photodynamic therapies.
abstract: Near-infrared (NIR) dyes, small organic molecules that function in the NIR region, have received increasing attention in recent years as diagnostic and therapeutic agents in the field of tumor research. They have been demonstrated great successes in imaging and treating tumors both in vitro and in vivo. And their different applications in clinical practices have made rapid gains. This review primarily focuses on the progress of the application of NIR dyes in tumor imaging and therapy. In particular, advances in the use of different NIR dyes in tumor-specific imaging, photothermal, and photodynamic therapies are discussed. Limitations and prospects associated with NIR dyes in diagnostic and therapeutic application are also reviewed.
authors.affiliation: State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P.R. China.
authors.forename: Ahu
authors.initials: A
authors.lastname: Yuan
authors.forename: Jinhui
authors.initials: J
authors.lastname: Wu
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Tang
authors.forename: Lili
authors.initials: L
authors.lastname: Zhao
authors.forename: Feng
authors.initials: F
authors.lastname: Xu
authors.forename: Yiqiao
authors.initials: Y
authors.lastname: Hu
mesh_terms: D000818:Animals; D004337:Drug Carriers; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D057054:Molecular Imaging / Q000379:methods*; D009369:Neoplasms / Q000175:diagnosis* / Q000188:drug therapy* / Q000378:metabolism; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000008:administration & dosage*; D011237:Predictive Value of Tests; D019265:Spectroscopy, Near-Infrared; D016896:Treatment Outcome
chemical_list: D004337:Drug Carriers; D005456:Fluorescent Dyes; D017319:Photosensitizing Agents