title: [Peculiarities of epilepsy in women with menstrual dysfunction].
abstract: An aim of the study was to optimize the diagnosis and treatment of epilepsy in women of reproductive age with concomitant disturbances of menstrual cycle. One hundred and thirty-two women, aged from 18 to 35 years, were studied. Menstrual dysfunction was found in 47,7% (n = 63): oligomenorrhea--in 68,3% (n = 43), amenorrhea--in 9,5% (n = 6) and dysfunctional metrorrhagia--in 22,2% (n = 14). Based on the character of hormone and ovarian dysfunction, the following syndromes were singled out: polycystic ovaries--54% (n = 34), isolated hypoprogesteronemia--23,8% (n = 15), hypercorticism--14,3% (n = 9), hypogonadotropic hypogonadism--7,9% (n = 5). Different hormonally-active drugs that allowed to normalize the menstrual cycle were used, along with basic antiepileptic drugs, to treat these hormonal dysfunctions and improve the course of epilepsy.
authors.forename: P N
authors.initials: PN
authors.lastname: Vlasov
authors.forename: V N
authors.initials: VN
authors.lastname: Iudaev
authors.forename: N V
authors.initials: NV
authors.lastname: Filatova
authors.forename: D V
authors.initials: DV
authors.lastname: Dranko
mesh_terms: D000293:Adolescent; D000308:Adrenocortical Hyperfunction / Q000150:complications; D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use*; D004827:Epilepsy / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007006:Hypogonadism / Q000150:complications; D008599:Menstruation Disturbances / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011085:Polycystic Ovary Syndrome; D011374:Progesterone / Q000097:blood; D055815:Young Adult
chemical_list: D000927:Anticonvulsants; D011374:Progesterone