title: Impact of vancomycin minimum inhibitory concentration on mortality among critically ill patients with methicillin-resistant Staphylococcus aureus bacteremia.
abstract: We retrospectively evaluated 99 intensive care unit patients with methicillin-resistant Staphylococcus aureus bacteremia to determine whether having a vancomycin minimum inhibitory concentration (MIC) of 2 mg/L affected mortality. This MIC was found in 5.1% of patients and was associated with the probability of death (adjusted odds ratio, 13.9 [95% confidence interval, 1.1-171.2]) independent of other factors.
authors.affiliation: Pulmonary and Critical Care Medicine Section, Washington Hospital Center, Washington, DC 20010, USA.
authors.forename: Christian J
authors.initials: CJ
authors.lastname: Woods
authors.forename: Anindita
authors.initials: A
authors.lastname: Chowdhury
authors.forename: Vinay M
authors.initials: VM
authors.lastname: Patel
authors.forename: Andrew F
authors.initials: AF
authors.lastname: Shorr
mesh_terms: D018806:APACHE; D000367:Age Factors; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy* / Q000382:microbiology / Q000401:mortality*; D016001:Confidence Intervals; D016638:Critical Illness; D004696:Endocarditis / Q000401:mortality; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D016017:Odds Ratio; D012121:Respiration, Artificial / Q000401:mortality; D012189:Retrospective Studies; D012769:Shock / Q000401:mortality; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology / Q000401:mortality*; D014640:Vancomycin / Q000627:therapeutic use*
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin