title: Nanogold-based bio-bar codes for label-free immunosensing of proteins coupling with an in situ DNA-based hybridization chain reaction.
abstract: A label-free, non-enzyme immunosensing strategy is designed for ultrasensitive electronic detection of disease-related proteins (carcinoembryonic antigen as a model) by using gold nanoparticle-based bio-bar codes and an in situ amplified DNA-based hybridization chain reaction.
authors.affiliation: MOE Key Laboratory of Analysis and Detection of Food Safety, Department of Chemistry, Fuzhou University, Fuzhou 350108, P. R. China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhou
authors.forename: Mingdi
authors.initials: M
authors.lastname: Xu
authors.forename: Dianping
authors.initials: D
authors.lastname: Tang
authors.forename: Zhuangqiang
authors.initials: Z
authors.lastname: Gao
authors.forename: Juan
authors.initials: J
authors.lastname: Tang
authors.forename: Guonan
authors.initials: G
authors.lastname: Chen
mesh_terms: D001483:Base Sequence; D015374:Biosensing Techniques / Q000379:methods*; D002272:Carcinoembryonic Antigen / Q000032:analysis; D015342:DNA Probes / Q000737:chemistry* / Q000235:genetics; D006046:Gold / Q000737:chemistry*; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D055029:Inverted Repeat Sequences; D053768:Metal Nanoparticles / Q000737:chemistry*; D009693:Nucleic Acid Hybridization / Q000379:methods*; D011506:Proteins / Q000032:analysis*
chemical_list: D002272:Carcinoembryonic Antigen; D015342:DNA Probes; D011506:Proteins; D006046:Gold