title: How to differentiate non-erosive reflux disease from functional heartburn.
abstract: Heartburn is a common symptom in gastroesophageal reflux disease. Endoscopic examination can differentiate between reflux esophagitis and non-erosive reflux disease (NERD), but not between NERD and functional heartburn. With the development of new techniques, more NERD patients could be identified among those previously diagnosed with functional heartburn. Most patients with NERD, however, could be identified based on their clinical characteristics and response to proton pump inhibitors and/or integrated anti-gastroesophageal reflux therapy.
authors.affiliation: Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, China. kemypumch2006@yahoo.com.cn
authors.forename: Mei Yun
authors.initials: MY
authors.lastname: Ke
mesh_terms: D003937:Diagnosis, Differential; D016099:Endoscopy, Gastrointestinal; D050782:Esophageal pH Monitoring; D005764:Gastroesophageal Reflux / Q000175:diagnosis* / Q000188:drug therapy*; D006356:Heartburn / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*
chemical_list: D054328:Proton Pump Inhibitors