title: Differential Go/NoGo activity in both contingent negative variation and spectral power.
abstract: We investigated whether both the contingent negative variation (CNV), an event-related potential index of preparatory brain activity, and event-related oscillatory EEG activity differentiated Go and NoGo trials in a delayed response task. CNV and spectral power (4-100 Hz) were calculated from EEG activity in the preparatory interval in 16 healthy adult participants. As previously reported, CNV amplitudes were higher in Go compared to NoGo trials. In addition, event-related spectral power of the Go condition was reduced in the theta to low gamma range compared to the NoGo condition, confirming that preparing to respond is associated with modulation of event-related spectral activity as well as the CNV. Altogether, the impact of the experimental manipulation on both slow event-related potentials and oscillatory EEG activity may reflect coordinated dynamic changes in the excitability of distributed neural networks involved in preparation.
authors.affiliation: Department of Neuropsychiatry and Psychosomatic Medicine, Division of Surgery and Clinical Neuroscience, Oslo University Hospital - Rikshospitalet, Norway. ingridfunderud@hotmail.com
authors.forename: Ingrid
authors.initials: I
authors.lastname: Funderud
authors.forename: Magnus
authors.initials: M
authors.lastname: Lindgren
authors.forename: Marianne
authors.initials: M
authors.lastname: Løvstad
authors.forename: Tor
authors.initials: T
authors.lastname: Endestad
authors.forename: Bradley
authors.initials: B
authors.lastname: Voytek
authors.forename: Robert T
authors.initials: RT
authors.lastname: Knight
authors.forename: Anne-Kristin
authors.initials: AK
authors.lastname: Solbakk
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology*; D003265:Contingent Negative Variation / Q000502:physiology*; D004569:Electroencephalography; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011597:Psychomotor Performance / Q000502:physiology