title: Pathologic basis of central nervous system infections.
abstract: Radiology provides valuable gross pathologic information about central nervous system (CNS) infections. Major categories of infectious lesions of the brain and spinal cord are recognized by imaging such as diffuse, focal, or multifocal. This article discusses the pathologic basis of these radiographic findings. It illustrates examples with gross and microscopic photographs of CNS infections, and the tissue reactions to these infections. Where the organism can spread within the CNS, and cellular responses to the organism underlie both the radiographic and pathologic findings.
authors.affiliation: Department of Pathology, University of Michigan Medical Center, Ann Arbor, MI 48109-5602, USA. paulmcke@umich.edu
authors.forename: Paul E
authors.initials: PE
authors.lastname: McKeever
mesh_terms: D001706:Biopsy; D001921:Brain / Q000473:pathology / Q000601:surgery; D002494:Central Nervous System Infections / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D003299:Cooperative Behavior; D003937:Diagnosis, Differential; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D033183:Interdisciplinary Communication; D008279:Magnetic Resonance Imaging; D013116:Spinal Cord / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed