title: Anaesthesia for direct laryngoscopy with propofol and fentanyl or sufentanil.
abstract: AIM #ENTITYSTARTX00026;
  
  
  OBJECTIVE
  To find if direct laryngoscopy (DL) could be done without using succinylcholine and secondly, to acertain the appropriate anesthetic regimen.
  
  
  METHODS
  In a double blind placebo controlled study 67 patients aged 40-75 years of age, of both sex requiring direct laryngoscopy (DL) either for diagnosis or for biopsy were enrolled. The patients were randomly divided in three groups. The patients in group F and S received Fentanyl or Sufentanil respectively along with Propofol, whereas those in group N received normal saline (placebo) and propofol. The conditions of laryngoscopy, hemodynamic parameters and any adverse events were recorded. Good or fair conditions for laryngoscopy were achieved in 91% (21), 87% (19) and 73% (16) of patients in groups F, S and N respectively (p < 0.05) in favor of group F and S. During DL arterial pressure and pulse rate changes were minimal when propofol was administered along with opioids, (group F and S) compared to group N where only propofol was used.
  
  
  RESULTS
  No serious side effects were seen in the three groups. Hence by these findings we concluded that better conditions of DL are achieved during anesthesia with propofol and fentanyl and sufentanil alone. The opioids provided additional benefit of stable hemodynamics.
authors.affiliation: Dept. of Anaesthesiology, S. N. Medical College, Agra, 282 001 India.
authors.forename: Uma
authors.initials: U
authors.lastname: Srivastava
authors.forename: Abhijeet Rajan
authors.initials: AR
authors.lastname: Mishra
authors.forename: Siddharth
authors.initials: S
authors.lastname: Sharma
authors.forename: Dharmendra
authors.initials: D
authors.lastname: Kumar
authors.forename: Aditya
authors.initials: A
authors.lastname: Kumar
authors.forename: S
authors.initials: S
authors.lastname: Saxena
authors.forename: Imran
authors.initials: I
authors.lastname: Khan
keywords: Direct Laryngoscopy; Fentanyl; Hemodynamic changes; Propofol; Sufentanil