title: Combined qualitative and quantitative research designs.
abstract: OBJECTIVE
  Mixed methods research designs have been recognized as important in addressing complexity and are recommended particularly in the development and evaluation of complex interventions. This article reports a review of studies in palliative care published between 2010 and March 2012 that combine qualitative and quantitative approaches.
  
  
  RESULTS
  A synthesis of approaches to mixed methods research taken in 28 examples of published research studies of relevance to palliative and supportive care is provided, using a typology based on a classic categorization put forward in 1992.
  
  
  CONCLUSIONS
  Mixed-method studies are becoming more frequently employed in palliative care research and resonate with the complexity of the palliative care endeavour. Undertaking mixed methods research requires a sophisticated understanding of the research process and recognition of some of the underlying complexities encountered when working with different traditions and perspectives on issues of: sampling, validity, reliability and rigour, different sources of data and different data collection and analysis techniques.
authors.affiliation: Queen's Medical Centre, School of Nursing, Midwifery and Physiotherapy, University of Nottingham, Nottingham, UK. jane.seymour@nottingham.ac.uk
authors.forename: Jane
authors.initials: J
authors.lastname: Seymour
mesh_terms: D006801:Humans; D010166:Palliative Care; D036301:Qualitative Research; D012107:Research Design