title: Laryngeal and voice disorders in patients with gastroesophageal symptoms. Correlation with pH-monitoring.
abstract: OBJECTIVE
  To investigate laryngeal and voice disorders in patients with gastroesophageal symptoms and their correlation with pH-monitoring.
  
  
  METHODS
  A prospective study was carried out in patients attended at the Voice Disorder Outpatient Clinics of Botucatu Medical School in a five-year period and had vocal and gastroesophagic symptoms. Patients underwent videolaryngoscopy, auditory-perceptual vocal analyses, computerized acoustic vocal analysis and dual probe pH-monitoring for 24 hours.
  
  
  RESULTS
  Fifty-seven patients were included (aged between 21 and 65 years; 45 women and 12 men), 18 had normal (31.6%) and 39 had abnormal pH-monitoring results (68.4%). Videolaryngoscopy recorded several laryngeal lesions for both patients with normal and abnormal pH-monitoring, but mostly for the latter group, highlighting posterior pachyderma. Auditory-perceptual vocal assessments identified vocal changes of several intensities for both groups but especially for patients with abnormal pH-monitoring results. All acoustic parameters, except f0, were abnormal for both groups, compared to the control population.
  
  
  CONCLUSIONS
  Acoustic and perceptual vocal changes and laryngeal lesions were recorded for both patients with normal pH-monitoring results and patients with abnormal pH-monitoring results, evidencing the importance of clinical history and videolaryngoscopic findings for diagnosing acid laryngitis.
authors.affiliation: Division of Otolaryngology, Department of Ophthalmology, Otolaryngology, Head and Neck Surgery, FMB, UNESP, Botucatu-SP, Brazil. rmartins@fmb.unesp.br
authors.forename: Regina Helena Garcia
authors.initials: RH
authors.lastname: Martins
authors.forename: Anete
authors.initials: A
authors.lastname: Branco
authors.forename: Elaine Lara Mendes
authors.initials: EL
authors.lastname: Tavares
authors.forename: Renata Mizusaki
authors.initials: RM
authors.lastname: Iyomasa
authors.forename: Lída Raquel de
authors.initials: LR
authors.lastname: Carvalho
authors.forename: Maria Aparecida de Arruda
authors.initials: MA
authors.lastname: Henry
mesh_terms: D000328:Adult; D000368:Aged; D001307:Auditory Perception; D050782:Esophageal pH Monitoring; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007818:Laryngeal Diseases / Q000209:etiology / Q000503:physiopathology*; D007828:Laryngoscopy / Q000379:methods; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013997:Time Factors; D014827:Vocal Cords; D014832:Voice Disorders / Q000209:etiology / Q000503:physiopathology*; D055815:Young Adult