title: Potassium iodide catalyzed simultaneous C3-formylation and N-aminomethylation of indoles with 4-substituted-N,N-dimethylanilines.
abstract: A one-pot dual functionalization of indoles has been developed. The simultaneous C3-formylation and N-aminomethylation of indoles can be achieved using readily available potassium iodide as a catalyst and tert-butyl peroxybenzoate as a co-oxidant.
authors.affiliation: State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, 94 Weijin Road, Tianjin 300071, China.
authors.forename: Lan-Tao
authors.initials: LT
authors.lastname: Li
authors.forename: Hong-Ying
authors.initials: HY
authors.lastname: Li
authors.forename: Li-Juan
authors.initials: LJ
authors.lastname: Xing
authors.forename: Li-Juan
authors.initials: LJ
authors.lastname: Wen
authors.forename: Peng
authors.initials: P
authors.lastname: Wang
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
mesh_terms: D000588:Amines / Q000737:chemistry*; D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000737:chemistry*; D008745:Methylation; D015394:Molecular Structure; D011193:Potassium Iodide / Q000737:chemistry*
chemical_list: D000588:Amines; D000814:Aniline Compounds; D007211:Indoles; D011193:Potassium Iodide; C021313:methylaniline