title: Flip-flopping to the membrane.
abstract: Excitatory synapses that use the neurotransmitter glutamate are highly dynamic, constantly changing their character in an activity-dependent manner. In this issue of Neuron, Penn et al. (2012) describe a novel mechanism that changes the fidelity of glutamate signaling to maintain homeostatic synaptic plasticity.
authors.affiliation: Department of Neurobiology and Behavior & Center for Nervous System Disorders, Stony Brook University, Stony Brook, NY 11794-5230, USA.
authors.forename: Catherine L
authors.initials: CL
authors.lastname: Salussolia
authors.forename: Lonnie P
authors.initials: LP
authors.lastname: Wollmuth