title: NMR spectroscopy: an excellent tool to understand RNA and carbohydrate recognition by proteins.
abstract: Structural biology plays a key role in understanding how networks of protein interactions with their partners are organized at the atomic level. In this review, we show that NMR is a very efficient method to solve 3D structures of protein - RNA and protein-carbohydrate complexes  of high quality. We explain the importance of studying such interactions and describe the main steps that are required to determine structures of these types of complexes by NMR. Finally, we show that X-ray crystallography and NMR are complementary methods and briefly report on advantages  and disadvantages of each approach.
authors.affiliation: Institute for Molecular Biology and Biophysics ETH Zürich CH-8093 Zürich, Switzerland.
authors.forename: Antoine
authors.initials: A
authors.lastname: Cléry
authors.forename: Mario
authors.initials: M
authors.lastname: Schubert
authors.forename: Frédéric H-T
authors.initials: FH
authors.lastname: Allain
mesh_terms: D002241:Carbohydrates / Q000737:chemistry*; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular / Q000379:methods*; D011506:Proteins / Q000737:chemistry*; D012313:RNA / Q000737:chemistry*
chemical_list: D002241:Carbohydrates; D011506:Proteins; D012313:RNA