title: Successful treatment of parenteral nutrition-associated liver disease in an adult by use of a fish oil-based lipid source.
abstract: Liver disease occurs in 15% to 40% of adults on long-term parenteral nutrition, with steatosis being more common than cholestasis in the adult population. This problem has been well reported in the pediatric population, but we describe the case of a man who became profoundly jaundiced after being on parenteral nutrition for 3 y and responded rapidly to a change in lipid source from soybean and olive oil-based emulsion (ClinOleic) to a fish oil-based lipid emulsion (Omegaven).
authors.affiliation: Department of Gastroenterology, North Shore Hospital, Takapuna, Auckland, New Zealand.
authors.forename: Esra
authors.initials: E
authors.lastname: Venecourt-Jackson
authors.forename: Simon J
authors.initials: SJ
authors.lastname: Hill
authors.forename: Russell S
authors.initials: RS
authors.lastname: Walmsley
mesh_terms: D005217:Fat Emulsions, Intravenous / Q000008:administration & dosage*; D005395:Fish Oils / Q000008:administration & dosage*; D006801:Humans; D007565:Jaundice / Q000209:etiology / Q000628:therapy; D008107:Liver Diseases / Q000209:etiology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010288:Parenteral Nutrition / Q000009:adverse effects*; D010938:Plant Oils / Q000008:administration & dosage; D013024:Soybean Oil / Q000008:administration & dosage; D014280:Triglycerides
chemical_list: C568346:ClinOleic; D005217:Fat Emulsions, Intravenous; D005395:Fish Oils; D010938:Plant Oils; D014280:Triglycerides; C568345:fish oil triglycerides; D013024:Soybean Oil