title: Tocilizumab in a patient with tophaceous gout resistant to treatment.
abstract: Gout is a disease characterized by acute episodes of pain, which occurs as the result of monosodic urate crystal deposit in the joint and periarticular tissue. In some cases, gout behaves as a severe inflammatory arthopathy that is difficult to manage, generating structural joint damage and functional impairment. We report the case of a 44 years old man with gouty arthritis for 12 years, not responding to NSAIDs, alopurinol, colchicine or corticosteroids. Tocilizumab was started with favorable clinical and laboratory results after treatment.
authors.affiliation: Unidad de Reumatología, Departamento de Medicina Interna, Hospital Universitario San Ignacio, Pontificia Universidad Javeriana, Bogotá, Colombia.
authors.forename: Jessica L
authors.initials: JL
authors.lastname: Pinto
authors.forename: Gloria E
authors.initials: GE
authors.lastname: Mora
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Fernández-Avila
authors.forename: Juan M
authors.initials: JM
authors.lastname: Gutiérrez
authors.forename: María C
authors.initials: MC
authors.lastname: Díaz
mesh_terms: D000328:Adult; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D015210:Arthritis, Gouty / Q000188:drug therapy*; D006801:Humans; D008297:Male
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D018501:Antirheumatic Agents; C502936:tocilizumab