title: [Exercise-induced oedema due to hormone-containing intrauterine device].
abstract: BACKGROUND
  Oedema is a known adverse effect of the levonorgestrel-containing intrauterine device (Mirena IUD). However, exercise-induced oedema has not been described before.
  
  
  METHODS
  A 38-year-old woman presented with symptoms of diffuse, exercise-induced oedema and dyspnoea. Tests for heart failure and other causes of oedema showed no abnormalities. All symptoms resolved spontaneously after the patient initiated removal of the IUD.
  
  
  CONCLUSIONS
  The pathophysiology of exercise-induced oedema is still poorly understood. When confronted with a patient with oedema (induced by exercise or other cause), the most common causes must first be excluded. If no explanation can be found, then the effects of medication must not be overlooked.
authors.affiliation: St. Antonius Ziekenhuis, afd. Interne geneeskunde, Nieuwegein, the Netherlands. franssen.laurens@gmail.com
authors.forename: Laurens E
authors.initials: LE
authors.lastname: Franssen
authors.forename: Willem-Jan  W
authors.initials: WJ
authors.lastname: Bos
mesh_terms: D000328:Adult; D003271:Contraceptive Agents, Female / Q000009:adverse effects; D004487:Edema / Q000175:diagnosis / Q000209:etiology*; D015444:Exercise; D005260:Female; D006801:Humans; D007436:Intrauterine Devices, Medicated / Q000009:adverse effects*; D016912:Levonorgestrel / Q000009:adverse effects*
chemical_list: D003271:Contraceptive Agents, Female; D016912:Levonorgestrel