title: Synthesis of pyrazolo[5,1-a]isoquinolines via silver(I)-rhodium(I) cooperative catalysis in the reaction of N'-(2-alkynylbenzylidene)hydrazide with cycloprop-2-ene-1,1-dicarboxylate.
abstract: A tandem reaction between N'-(2-alkynylbenzylidene)hydrazide and cycloprop-2-ene-1,1-dicarboxylate co-catalyzed by silver triflate and tris(triphenylphosphine)rhodium chloride is reported. The reaction proceeds through 6-endo-cyclization, [3 + 2] cycloaddition, cyclopropane opening, and aromatization, leading to pyrazolo[5,1-a]isoquinolines in moderate to good yields.
authors.affiliation: Obstetrics and Gynecology Hospital, Fudan University, 419 Fangxie Road, Shanghai 200011, China. yaoliangqingcn@126.com
authors.forename: Liangqing
authors.initials: L
authors.lastname: Yao
authors.forename: Xingxin
authors.initials: X
authors.lastname: Yu
authors.forename: Chen
authors.initials: C
authors.lastname: Mo
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
mesh_terms: D001597:Benzylidene Compounds / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D003998:Dicarboxylic Acids / Q000737:chemistry*; D006834:Hydrazines / Q000737:chemistry*; D007546:Isoquinolines / Q000138:chemical synthesis*; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*
chemical_list: D001597:Benzylidene Compounds; D003998:Dicarboxylic Acids; D006834:Hydrazines; D007546:Isoquinolines; C029424:hydrazine; D012834:Silver; D012238:Rhodium