title: Renal function of renal transplantation patients after hospitalization in an intensive care unit.
abstract: Kidney transplantation is the favored method to treat end-stage renal disease. Some recipients develop severe diseases requiring admission to an intensive care unit (ICU). Acute kidney injury (AKI) is a common complication among critically ill patients but few data are available among renal transplant recipients. The aim of this monocenter retrospective study was to describe renal function in kidney transplant recipients admitted to an ICU and to evaluate their renal functional recovery after this stay. We identified all renal transplant recipients admitted to our medical ICU from January 1, 2001, to December 31, 2010: namely, 79 stays by 62 patients. We used the glomerular filtration rate criteria of the RIFLE classification to evaluate AKI during the ICU stay. During the ICU stay, 56 patients (70.9%) were classified as "no AKI" according to the RIFLE classification; 11 (13.9%) belonged to class R, 10 (12.7%) to class I, and 2 (2.5%) to class F. Overall, 24% of the patients needed dialysis during the ICU stay. Mortality rate at 3 months after the ICU stay was 25.3%. Among the patients who survived, 40 (68%) recovered to their baseline renal function at 3 months, most of them being classified as no AKI during the ICU stay. We have herein reported the evolution of renal function among kidney graft recipients after an ICU stay.
authors.affiliation: Service de réanimation médicale, CHU Bretonneau, Tours, France.
authors.forename: J
authors.initials: J
authors.lastname: Badin
authors.forename: H
authors.initials: H
authors.lastname: Longuet
authors.forename: A
authors.initials: A
authors.lastname: Guillon
authors.forename: C
authors.initials: C
authors.lastname: Barbet
authors.forename: J M
authors.initials: JM
authors.lastname: Halimi
authors.forename: Y
authors.initials: Y
authors.lastname: Lebranchu
authors.forename: D
authors.initials: D
authors.lastname: Perrotin
authors.forename: M
authors.initials: M
authors.lastname: Buchler
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality / Q000503:physiopathology / Q000628:therapy; D000368:Aged; D005260:Female; D005602:France; D005919:Glomerular Filtration Rate; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D007362:Intensive Care Units; D007668:Kidney / Q000503:physiopathology*; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000401:mortality; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D020127:Recovery of Function; D006435:Renal Dialysis; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome