title: Hypopituitarism and sphenoid surgery.
abstract: A middle-aged white man underwent sphenoid and ethmoid surgery for rhinitis with polyposis. Within days, he developed severe fatigue, myalgias and arthralgias. Initial testing demonstrated central hypogonadism, followed by a low normal insulin-like growth factor-1 and an abnormal L-dopamine growth hormone stimulation test result. As years past, the patient would have such recurrent symptoms when ill with the addition of nausea and vomiting. Testing, 7 years after his initial surgery, confirmed inappropriate thyroid and cortisol responses. His clinical symptoms have resolved with appropriate medical therapy. A review of the literature demonstrated no descriptions of hypopituitarism from sphenoid surgery.
authors.affiliation: Department of Internal Medicine, University of South Florida Morsani College of Medicine, Wesley Chapel, Florida 33543, USA. mflann5555@aol.com
authors.forename: Michael T
authors.initials: MT
authors.lastname: Flannery
authors.forename: Robert C
authors.initials: RC
authors.lastname: Flannery
mesh_terms: D006801:Humans; D007018:Hypopituitarism / Q000175:diagnosis* / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis* / Q000209:etiology*; D013100:Sphenoid Bone / Q000473:pathology / Q000601:surgery*