title: Toxic epidermal necrolysis caused by fluconazole in a patient with human immunodeficiency virus infection.
abstract: Stevens-Johnson syndrome and toxic epidermal necrolysis (TEN) are rare but serious dermatologic disorders. These grave conditions present as medical emergency, requiring prompt diagnosis and management. These are often drug induced and various groups of drugs, such as sulfa drugs, NSAIDS, etc., have been implicated as to cause TEN. Fluconazole is a commonly used drug with mild side effects. TEN caused by fluconazole is rare, and till now only few cases have been reported in the literature. We present a case of TEN in a human immunodeficiency virus infected man following fluconazole therapy in view of its rare occurrence.
authors.affiliation: Department of Respiratory Medicine, J. L. N. Medical College, Ajmer, Rajasthan and Himalayan Institute of Medical Sciences, Jollygrant, Dehradun, India.
authors.forename: Jacob
authors.initials: J
authors.lastname: George
authors.forename: Arun
authors.initials: A
authors.lastname: Sharma
authors.forename: Ramakant
authors.initials: R
authors.lastname: Dixit
authors.forename: Naveen
authors.initials: N
authors.lastname: Chhabra
authors.forename: Smita
authors.initials: S
authors.lastname: Sharma
keywords: Fluconazole; HIV infection; toxic epidermal necrolysis