title: [Comparative study of central and peripapillary retina in primary open-angle glaucoma using spectral-domain optical coherence tomography].
abstract: The aim of the study was to compare outer retinal layers in primary open-angle glaucoma (POAG) using spectral-domain optical coherence tomography (OCT). 15 patients (27 eyes) and 16 normal subjects (32 eyes) were examined. Patients were examined using OCT Spectralis ("Heidelberg Engineering", Germany) in order to analyze outer retinal layers and evaluate beta-zone extent. Significant difference such as thining of retinal pigment epithelium/Bruch's membrane (RPE/ BrM) complex was found in OCT images of outer retinal layers. Negative correlation of RPE/BrM complex thickness and peripapillary beta-zone extent was found. Changes of central and peripapillary retina detected using spectral-domain OCT may be considered for diagnosis and monitoring of POAG.
authors.forename: V V
authors.initials: VV
authors.lastname: Strakhov
authors.forename: V V
authors.initials: VV
authors.lastname: Alekseev
authors.forename: A V
authors.initials: AV
authors.lastname: Iartsev
mesh_terms: D000368:Aged; D005260:Female; D005584:Fovea Centralis / Q000473:pathology*; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D009898:Optic Disk / Q000473:pathology; D015203:Reproducibility of Results; D055213:Retinal Pigment Epithelium / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods*