title: Surface Modification of Poly(amidoamine) (PAMAM) Dendrimer as Antimicrobial Agents.
abstract: Poly(amidoamine) (PAMAM) (G3) dendrimer was modified into quaternary ammonium salts using tertiary amines with different chain lengths: dimethyldodecyl amine, dimethylhexyl amine, and dimethylbutyl amine using an efficient synthetic route. The antimicrobial activity of these dendrimer ammonium salts against Staphylococcus and E-coli bacteria was examined using the disc diffusion method. It was found that quaternary ammonium salt prepared with the dimethyldodecyl amine exhibits antimicrobial efficacy against Staphalococus and E.coli bacteria.
authors.affiliation: Department of Chemistry, Long Island University, Brooklyn, NY 11201.
authors.forename: Shakira
authors.initials: S
authors.lastname: Charles
authors.forename: Nadarajah
authors.initials: N
authors.lastname: Vasanthan
authors.forename: Dong
authors.initials: D
authors.lastname: Kwon
authors.forename: Gabriela
authors.initials: G
authors.lastname: Sekosan
authors.forename: Subhas
authors.initials: S
authors.lastname: Ghosh