title: [Mucoepidermoid carcinoma of the intrahepatic bile duct with metastasis to the cranial skin].
abstract: Mucoepidermoid carcinoma of the intrahepatic bile duct is a rare variant of cholangiocarcinoma: it is composed of mucus-secreting squamous cells and glandular cells within the same nests. This tumor is very aggressive, with high-grade malignancy, and has a poor prognosis. In the international literature, only 17 cases of mucoepidermoid carcinoma originating in the hepatic bile duct system have been reported until now. We report an autopsy case of mucoepidermoid carcinoma of the intrahepatic bile duct with metastasis to the cranial skin in a Japanese man who was more than 70 years old. This cancer metastasizes to many organs, but skin metastasis is extremely rare.
authors.affiliation: Department of Gastroenterology, Matsuyama-shimin Hospital. mari.nishiyama@sky.plala.or.jp
authors.forename: Mari
authors.initials: M
authors.lastname: Nishiyama
authors.forename: Yuji
authors.initials: Y
authors.lastname: Mizukami
authors.forename: Misaki
authors.initials: M
authors.lastname: Kume
authors.forename: Akiko
authors.initials: A
authors.lastname: Ogawa
authors.forename: Akiko
authors.initials: A
authors.lastname: Jinno
authors.forename: Yoshiyasu
authors.initials: Y
authors.lastname: Kisaka
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Shinzo
authors.initials: S
authors.lastname: Murakami
authors.forename: Yuji
authors.initials: Y
authors.lastname: Ohtsuki
mesh_terms: D000368:Aged; D001650:Bile Duct Neoplasms / Q000473:pathology*; D001653:Bile Ducts, Intrahepatic; D018277:Carcinoma, Mucoepidermoid / Q000473:pathology*; D006258:Head and Neck Neoplasms / Q000556:secondary*; D006801:Humans; D008297:Male; D012535:Scalp; D012878:Skin Neoplasms / Q000556:secondary*