title: Inaugural severe vaso-occlusive retinopathy in systemic lupus erythematosus.
abstract: Purpose To report the case of a patient with an inaugural severe bilateral vaso-occlusive retinopathy due to systemic lupus erythematosus. Method Clinical examination, fundus pictures and fluorescein angiography were performed. Results A 26-year-old, healthy, African man presented with a meningo-encephalitic syndrome and a severe bilateral visual impairment. The fundus examination revealed multiple retinal vascular occlusions, and a fluorescein angiography showed retinal and choroidal ischemia bilaterally. In addition, based on the neurologic disorders, a pleuritis, a renal disorder and a hematologic disorder, systemic lupus erythematosus, was diagnosed. Conclusions Severe vaso-occlusive retinopathy in a 26-year-old man resulting in a significant visual loss as the initial manifestation of systemic lupus erythematosus. Central nervous system involvement during lupus might be more frequent in patients when serious retinal changes occur.
authors.affiliation: Department of Ophthalmology, Avicenne Hospital, 125 Rue de Stalingrad, 93000, Bobigny, France. audreygiocanti@yahoo.fr
authors.forename: Audrey
authors.initials: A
authors.lastname: Giocanti-Auregan
authors.forename: Typhaine
authors.initials: T
authors.lastname: Grenet
authors.forename: Charlotte
authors.initials: C
authors.lastname: Rohart
authors.forename: Isabelle
authors.initials: I
authors.lastname: Badelon
authors.forename: Gilles
authors.initials: G
authors.lastname: Chaine
mesh_terms: D000328:Adult; D015862:Choroid Diseases / Q000209:etiology*; D006801:Humans; D007511:Ischemia / Q000209:etiology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008297:Male; D015356:Retinal Artery Occlusion / Q000209:etiology*; D015861:Retinal Neovascularization / Q000209:etiology*