title: Minimising blood loss and transfusion in contemporary hip and knee arthroplasty.
abstract: Despite advances in contemporary hip and knee   arthroplasty, blood loss continues to be an issue. Though blood transfusion   has long been used to treat post-operative anemia, the associated   risks are well established. The objective of this article is to   present two practical and effective approaches to minimising blood   loss and transfusion rates in hip and knee arthroplasty: the use   of antifibrinolytic medications such as tranexamic acid and the   adoption of more conservative transfusion indications.
authors.affiliation: Mayo Clinic, 200 First Street, Rochester, Minnesota 55944, USA.
authors.forename: C D
authors.initials: CD
authors.lastname: Watts
authors.forename: M W
authors.initials: MW
authors.lastname: Pagnano
mesh_terms: D000740:Anemia / Q000209:etiology / Q000517:prevention & control / Q000628:therapy; D000933:Antifibrinolytic Agents / Q000627:therapeutic use*; D019644:Arthroplasty, Replacement, Hip; D019645:Arthroplasty, Replacement, Knee; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001803:Blood Transfusion / Q000592:standards*; D006488:Hemostasis, Surgical / Q000379:methods*; D006801:Humans; D019990:Perioperative Care; D011183:Postoperative Complications / Q000517:prevention & control / Q000628:therapy; D014148:Tranexamic Acid / Q000627:therapeutic use*; D065227:Transfusion Reaction
chemical_list: D000933:Antifibrinolytic Agents; D014148:Tranexamic Acid