title: [Hyperhaemolytic siyndrome in patient without haemoglobinopathies].
abstract: Hyperhemolysis syndrome usually occurs in patients with sickle cell disease and possibly thalassemia who receive multiple transfusions. There are only few clinical reports on patients without hemoglobinopathies as in this report. Our patient was diagnosed with hyperhemolytic reaction and was infused with IVIG and methylprednisolone for several days. Signs of tissue hypoxia developed along with increased cardiac enzymes, hepatocellular and cerebrovascular injury, and finally death. On autopsy, there was no evidence for hemolytic uremic syndrome or thrombotic thrombocytopenic purpura.
authors.affiliation: Merkur University Hospital, Department of Internal Medicine, Zagreb, Croatia. ingrid.prkacin@gmail.com
authors.forename: Ingrid
authors.initials: I
authors.lastname: Prkacin
authors.forename: Jasna
authors.initials: J
authors.lastname: Mesarić
authors.forename: Gordana
authors.initials: G
authors.lastname: Cavrić
authors.forename: Silvana
authors.initials: S
authors.lastname: Jurenec
authors.forename: Zeljka
authors.initials: Z
authors.lastname: Hundrić-Haspl
authors.forename: Ika
authors.initials: I
authors.lastname: Kardum-Skelin
mesh_terms: D000368:Aged; D000743:Anemia, Hemolytic / Q000097:blood*; D001323:Autoantibodies / Q000032:analysis; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D006461:Hemolysis; D006801:Humans; D013577:Syndrome
chemical_list: D001323:Autoantibodies