title: Application of hyperdry amniotic membrane patches without fibrin glue over the bony surface of mastoid cavities in canal wall down tympanoplasty.
abstract: CONCLUSIONS
  Fibrin glue might be an inessential bioadhesive for attachment of hyperdry amniotic membrane (AM) patches in canal wall down (CWD) tympanoplasty.
  
  
  OBJECTIVE
  To clarify the pliability and adherence capability of human hyperdry AM, the feasibility of fixing hyperdry AM without fibrin glue to the bony surface of the mastoid cavity was evaluated in CWD tympanoplasty.
  
  
  METHODS
  This was a retrospective chart review. In seven ears of seven patients, the AM was simply attached over the bony surface of the mastoid cavity without fibrin glue (AMG(-) group). In 22 ears of 20 other patients, hyperdry AM (11 ears of 11 patients, AMG(+) group) or temporal fascia (11 ears of 9 patients, TFG(+) group) was attached over the bony surface of the mastoid cavity with fibrin glue. Times for graft epithelization were compared among the three groups.
  
  
  RESULTS
  Complete epithelization of the mastoid cavity took place in all patients in all three groups. The mean time to complete epithelization of the graft in the AMG(-) and AMG(+) groups was significantly faster than that in the TFG(+) group (p < 0.05) and was not significantly different between the two AM groups (p > 0.05).
authors.affiliation: Department of Otolaryngology, University of Toyama, Toyama, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kanazawa
authors.forename: Hideo
authors.initials: H
authors.lastname: Shojaku
authors.forename: Motonori
authors.initials: M
authors.lastname: Okabe
authors.forename: Michiro
authors.initials: M
authors.lastname: Fujisaka
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Takakura
authors.forename: Hirohiko
authors.initials: H
authors.lastname: Tachino
authors.forename: Masahito
authors.initials: M
authors.lastname: Tsubota
authors.forename: Yukio
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Toshio
authors.initials: T
authors.lastname: Nikaido
mesh_terms: D000328:Adult; D000368:Aged; D001684:Biological Dressings; D055762:Cranial Fontanelles / Q000601:surgery*; D003890:Desiccation; D005240:Feasibility Studies; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D062326:Re-Epithelialization / Q000502:physiology; D012189:Retrospective Studies; D014014:Tissue Adhesives / Q000008:administration & dosage*; D014433:Tympanoplasty / Q000379:methods*
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives