title: [Chemical constituents and antibacterial activity contained in Caesalpinia millettii].
abstract: To study chemical constituents contained in roots of Caesalpinia millettii by HPLC. Six homoisoflavonoids were identified by spectroscopic data and physicochemical property as eucomin (1), intricatinol (2), 8-methoxybonducellin (3), bonducellin (4), 8-methoxyisobonducellin (5) and 3-(4-methoxybenzyl) -5, 7-dimethoxychroman-4-one (6). All compounds were separated from the root of this genus for the first time. An antibacterial screening was made on eight monomeric compounds. Among them, 8-methoxyisobonducellin, intricatinol, bergenin, hyperoside and 11-O-galloylbergenin showed a inhibitory effect on Staphylococcus aureus, Klebsiella Peneumoniae, Beta streptococcus and Aeruginosus bacillus.
authors.affiliation: College of Life Science, Jilin Agricultural University, Changchun 130118, China. chenping2009@yahoo.com.cn
authors.forename: Ping
authors.initials: P
authors.lastname: Chen
authors.forename: Jun
authors.initials: J
authors.lastname: Lei
authors.forename: Xudong
authors.initials: X
authors.lastname: Xu
authors.forename: Junshan
authors.initials: J
authors.lastname: Yang
mesh_terms: D000900:Anti-Bacterial Agents / Q000032:analysis*; D029911:Caesalpinia / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D007529:Isoflavones / Q000032:analysis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D018517:Plant Roots / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D007529:Isoflavones