title: Left main coronary artery thrombus resulting from combined protein C and S deficiency.
abstract: Inherited hypercoagulopathies such as protein C and S deficiency usually lead to the formation of venous thrombi in clinical practice; however, they rarely lead to arterial thrombosis. It has been demonstrated that both protein C and S deficiency may lead to myocardial infarctions. However, our literature review revealed no reports of left main coronary artery thrombi caused by protein C and S deficiency. This paper presents a case of a left main coronary artery thrombus resulting from protein C and S deficiency in a young patient with normal coronary arteries.
authors.affiliation: Department of Cardiology, Bulent Ecevit University, School of Medicine, Turkey. sayinmr@mynet.com
authors.forename: Muhammet R
authors.initials: MR
authors.lastname: Sayin
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Akpinar
authors.forename: Turgut
authors.initials: T
authors.lastname: Karabag
authors.forename: Mustafa
authors.initials: M
authors.lastname: Aydin
authors.forename: Sait M
authors.initials: SM
authors.lastname: Dogan
authors.forename: Cem
authors.initials: C
authors.lastname: Cil
mesh_terms: D000328:Adult; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D004562:Electrocardiography; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D020151:Protein C Deficiency / Q000097:blood / Q000150:complications*; D018455:Protein S Deficiency / Q000097:blood / Q000150:complications*; D000077466:Tirofiban; D014443:Tyrosine / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D005343:Fibrinolytic Agents; D014443:Tyrosine; D000077466:Tirofiban