title: [The action of hydrogen peroxide on mutants of Streptomyces globisporus 1912 with different carotene-synthesizing activity].
abstract: The paper deals with dependence of survival of Crt(+)- and Crt- mutants of Streptomyces globisporus 1912 in conditions of oxidizing stress caused by hydrogen peroxide on the level of lycopene and beta-carotene biosynthesis. Pink mutants 4Lcp, RVLcp and R3Lcp, which produce lycopene, are the most resistant to hydrogen peroxide. Red mutants 4Crt, 6Crt, 7Crt, 7Y RVCrt, R3Crt--producers of lycopene and beta-carotene have the average level of resistance to H2O2. Pigmentless mutants (Crt-) 4W, 4W1, 7W2 and yellow one 7Y have preserved sensitivity to H2O2 characteristic of the initial strain 1912.
authors.forename: V Ia
authors.initials: VIa
authors.lastname: Lavrinchuk
authors.forename: S L
authors.initials: SL
authors.lastname: Holembiovs'ka
authors.forename: B P
authors.initials: BP
authors.lastname: Matseliukh
mesh_terms: D002338:Carotenoids / Q000096:biosynthesis* / Q000235:genetics; D002855:Chromatography, Thin Layer; D003470:Culture Media; D004305:Dose-Response Relationship, Drug; D017353:Gene Deletion; D005798:Genes, Bacterial; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D000077276:Lycopene; D050296:Microbial Viability / Q000187:drug effects; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D013302:Streptomyces / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D019207:beta Carotene / Q000096:biosynthesis* / Q000235:genetics
chemical_list: D003470:Culture Media; D019207:beta Carotene; D002338:Carotenoids; D006861:Hydrogen Peroxide; D000077276:Lycopene