title: Cataracts and Dupuytren disease: a case report and review of the literature.
abstract: Purpose. Dupuytren disease is an inherited proliferative and progressive connective disease. Ectopic disease may, however, be located distant from the palmar fascia.  Methods. Case report and review of the literature.  Results. We describe a case of symmetric bilateral posterior subcapsular cataracts associated with symmetric bilateral Dupuytren disease and symmetric bilateral Ledderhose disease in a 56-year-old Caucasian man. His medical history was negative for glucocorticoids intake, diabetes, and exposure to radiation. Serum transforming growth factor β (TGF-β)1 concentration has been evaluated and was found to be almost double compared to the controls.  Conclusions. We speculate that the TGF-β plays an important role for ocular and connective tissue disorders.
authors.affiliation: University Eye Clinic, Foundation IRCCS Policlinico San Matteo, Pavia - Italy.
authors.forename: Carlo A
authors.initials: CA
authors.lastname: Cutolo
authors.forename: Sara
authors.initials: S
authors.lastname: Lombardo
authors.forename: Alice C
authors.initials: AC
authors.lastname: Verticchio Vercellin
authors.forename: Chiara
authors.initials: C
authors.lastname: Bertone
authors.forename: Mara
authors.initials: M
authors.lastname: De Amici
authors.forename: Elena
authors.initials: E
authors.lastname: Antoniazzi
authors.forename: Giovanni
authors.initials: G
authors.lastname: Milano