title: A fatal case due to cough syrup abuse.
abstract: We describe here a fatal abused case of cough syrup, containing chlorpheniramine and dihydrocodeine. Postmortem blood concentration of chlorpheniramine was above fatal levels, but dihydrocodeine concentration was within a therapeutic ranges, and those drug levels in blood were discussed from the viewpoint of forensic pharmacokinetics. We concluded that the cause death was due to the chlorpheniramine poisoning.
  
  
  BACKGROUND
  cough syrup abuse - chlorpheniramine - dihydrocodeine.
authors.affiliation: Department of Forensic Medicine, Faculty of Medicine, Kagawa University, Japan. kinochin@med.kagawa-u.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Kinoshita
authors.forename: N
authors.initials: N
authors.lastname: Tanaka
authors.forename: M
authors.initials: M
authors.lastname: Jamal
authors.forename: M
authors.initials: M
authors.lastname: Kumihashi
authors.forename: R
authors.initials: R
authors.lastname: Okuzono
authors.forename: K
authors.initials: K
authors.lastname: Ameno
mesh_terms: D000328:Adult; D000996:Antitussive Agents / Q000506:poisoning*; D002744:Chlorpheniramine / Q000506:poisoning*; D003061:Codeine / Q000031:analogs & derivatives* / Q000506:poisoning; D005260:Female; D006801:Humans
chemical_list: D000996:Antitussive Agents; D002744:Chlorpheniramine; C014481:dihydrocodeine; D003061:Codeine