title: Biphasic anaphylaxis to gemifloxacin.
abstract: Anaphylaxis have been documented as adverse effects of ciprofloxacin, ofloxacin, norfloxacin, levofloxacin, and moxifloxacin. However resistant and biphasic anaphlylactic reactions to gemifloxacin have not been reported to date. Management of severe anaphylaxis in the elderly can be complicated by concurrent medications such as beta (β) adrenergic, alpha (α) adrenergic blockers and angiotensin-converting enzyme (ACE) inhibitors. We report here in the case of a 60-year-old male who was taking on ACE inhibitor, α and β blockers and experienced a severe, resistant and biphasic anaphlylactic reaction to gemifloxacin mesylate.
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Erciyes University, Kayseri 38030, Turkey.
authors.forename: Insu
authors.initials: I
authors.lastname: Yilmaz
authors.forename: Serkan
authors.initials: S
authors.lastname: Doğan
authors.forename: Nuri
authors.initials: N
authors.lastname: Tutar
authors.forename: Asiye
authors.initials: A
authors.lastname: Kanbay
authors.forename: Hakan
authors.initials: H
authors.lastname: Büyükoğlan
authors.forename: Ramazan
authors.initials: R
authors.lastname: Demir
keywords: ACE inhibitor; Alpha blocker; Beta blocker; Biphasic anaphylaxis; Gemifloxacin