title: Phenolics and their antifungal role in grapevine wood decay: focus on the Botryosphaeriaceae family.
abstract: The interaction between  Vitis vinifera  and trunk disease fungi requires better understanding. We studied the role of phenolics as possible plant defense compounds in this context. The impact of 24 grapevine phenolic compounds was determined on 6 major wood decay fungi by an in vitro agar plate assay. Hydroxystilbenoids, especially oligomers such as miyabenol C, isohopeaphenol, and vitisin A and B, greatly reduced the growth of the fungi, except that of  Phaeoacremonium aleophilum . A detailed investigation in 10 Botryosphaeriaceae strains revealed that all of the studied members of this family display a common susceptibility to phenolics that is more or less significant. Then we undertook a quantitative analysis of stilbenoid content in grapevine plantlets inoculated with Botryosphaeriaceae to investigate whether in planta these fungi have to counteract the most active phenolics. On the basis of our results, the possible role of phenolics in grapevine defense against trunk disease agents is discussed.
authors.affiliation: Université de Bordeaux, Groupe d'Etude des Substances Végétales à Activité Biologique (GESVAB), EA 3675, Institut des Sciences de la Vigne et du Vin, 210 Chemin de Leysotte, CS 50008, F-33882 Villenave d'Ornon Cedex, France.
authors.forename: Carole
authors.initials: C
authors.lastname: Lambert
authors.forename: Jonathan
authors.initials: J
authors.lastname: Bisson
authors.forename: Pierre
authors.initials: P
authors.lastname: Waffo-Téguo
authors.forename: Yorgos
authors.initials: Y
authors.lastname: Papastamoulis
authors.forename: Tristan
authors.initials: T
authors.lastname: Richard
authors.forename: Marie-France
authors.initials: MF
authors.lastname: Corio-Costet
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Mérillon
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Cluzet
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D001203:Ascomycota / Q000187:drug effects* / Q000472:pathogenicity*; D001572:Benzofurans / Q000494:pharmacology; D054884:Host-Pathogen Interactions / Q000502:physiology; D020128:Inhibitory Concentration 50; D010636:Phenols / Q000494:pharmacology*; D010935:Plant Diseases / Q000382:microbiology*; D018547:Plant Stems / Q000382:microbiology*; D013267:Stilbenes / Q000032:analysis / Q000378:metabolism / Q000494:pharmacology; D027843:Vitis / Q000382:microbiology*; D014920:Wine; D014934:Wood / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D001572:Benzofurans; D010636:Phenols; D013267:Stilbenes; C480486:malvidin-3-O-glucoside-4 vinyl; C585842:miyabenol C; C412469:vitisin A; C107773:pterostilbene