title: A quantitative and novel approach to the prioritization of zoonotic diseases in North America: a public perspective.
abstract: BACKGROUND
  Zoonoses account for over half of all communicable diseases causing illness in humans. As there are limited resources available for the control and prevention of zoonotic diseases, a framework for their prioritization is necessary to ensure resources are directed into those of highest importance. Although zoonotic outbreaks are a significant burden of disease in North America, the systematic prioritization of zoonoses in this region has not been previously evaluated.
  
  
  RESULTS
  This study describes the novel use of a well-established quantitative method, conjoint analysis (CA), to identify the relative importance of 21 key characteristics of zoonotic diseases that can be used for their prioritization in Canada and the US. Relative importance weights from the CA were used to develop a point-scoring system to derive a recommended list of zoonoses for prioritization in Canada and the US. Over 1,500 participants from the general public were recruited to complete the online survey (761 from Canada and 778 from the US). Hierarchical Bayes models were fitted to the survey data to derive CA-weighted scores. Scores were applied to 62 zoonotic diseases of public health importance in Canada and the US to rank diseases in order of priority.
  
  
  CONCLUSIONS
  This was the first study to describe a systematic and quantitative approach to the prioritization of zoonoses in North America involving public participants. We found individuals with no prior knowledge or experience in prioritizing zoonoses were capable of producing meaningful results using CA as a novel quantitative approach to prioritization. More similarities than differences were observed between countries suggesting general agreement in disease prioritization between Canadians and Americans. We demonstrate CA as a potential tool for the prioritization of zoonoses; other prioritization exercises may also consider this approach.
authors.affiliation: Centre for Public Health and Zoonoses, Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Canada. vng03@uoguelph.ca
authors.forename: Victoria
authors.initials: V
authors.lastname: Ng
authors.forename: Jan M
authors.initials: JM
authors.lastname: Sargeant
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002170:Canada; D003140:Communicable Disease Control; D003141:Communicable Diseases / Q000453:epidemiology; D004196:Disease Outbreaks; D005260:Female; D017144:Focus Groups; D005843:Geography; D006801:Humans; D008297:Male; D008875:Middle Aged; D015233:Models, Statistical; D011634:Public Health; D014481:United States; D055815:Young Adult; D015047:Zoonoses / Q000453:epidemiology*