title: Systemic inflammatory response syndrome outcome in surgical patients.
abstract: BACKGROUND
  The problems of inflammation and infection as a leading cause of organ dysfunction and failure is a major problem after injury or operations. When systemic inflammatory response syndrome (SIRS) progress to multiple organ failure (MOF), the mortality reach up to 30-80% depending on the number of failed organs. Recent discoveries and improvement in patient care, a reasonable question then arises, are the incidence of MOF decreasing? The literature suggests a decrease in mortality of patients with severe organ failure and a decrease in elective surgical mortality in patients.
  
  
  METHODS
  This is prospective study of 50 patients who underwent surgical procedure. They were followed up till date of termination with daily SIRS monitoring, development of MODS and MOF. Risk factors for MOF are addressed.
  
  
  RESULTS
  There are total 31 patients who develop SIRS, of whom 7 patients develop severe sepsis and 4 went into MOF.
  
  
  CONCLUSIONS
  Early detection of SIRS helps us to prevent multiple organ dysfunction syndrome (MODS)/MOF, leading to lesser hospital stay and better outcome.
authors.affiliation: Department of General Surgery, Dr D.Y. Patil Medical College, Hospital & Research Centre, Pimpri, Pune, Maharashtra India.
authors.forename: Simrandeep
authors.initials: S
authors.lastname: Singh
authors.forename: Pradeep
authors.initials: P
authors.lastname: Singh
authors.forename: Gurjit
authors.initials: G
authors.lastname: Singh
keywords: MODS; MOF; SIRS