title: DNA surface coating of calixarene-based nanoparticles: a sequence-dependent binding mechanism.
abstract: An amphiphilic calix[4]arene derivative bearing four guanidino moieties at the upper rim and four dodecyl chains at the lower rim was shown to form stable solid lipid nanoparticles (SLNs) in water. The study of the interactions of these cationic SLNs with DNA revealed a sequence-dependent groove binding mechanism.
authors.affiliation: University of Applied Sciences and Arts Northwestern Switzerland, Gründenstrasse 40, CH-4132 Muttenz, Switzerland.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Rullaud
authors.forename: Michael
authors.initials: M
authors.lastname: Siragusa
authors.forename: Alessandro
authors.initials: A
authors.lastname: Cumbo
authors.forename: Daniel
authors.initials: D
authors.lastname: Gygax
authors.forename: Patrick
authors.initials: P
authors.lastname: Shahgaldian
mesh_terms: D001483:Base Sequence; D047250:Calixarenes / Q000737:chemistry*; D004247:DNA / Q000737:chemistry* / Q000235:genetics*; D008055:Lipids / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*; D055672:Static Electricity
chemical_list: D008055:Lipids; D010636:Phenols; C121325:calix(4)arene; D047250:Calixarenes; D004247:DNA