title: The ProSeal Laryngeal Mask Airway is more effective than the LMA-Classic in pediatric anesthesia: a meta-analysis.
abstract: OBJECTIVE
  To determine, in pediatric patients, whether the ProSeal Laryngeal Mask Airway (PLMA) has advantages over the LMA-Classic (cLMA) in leak pressure, placement difficulty, incidence of adverse events, postoperative blood staining, laryngospasm, bronchospasm, and hoarseness.
  
  
  METHODS
  Meta-analysis.
  
  
  METHODS
  Metropolitan university medical center.
  
  
  METHODS
  MEDLINE (1966-2011), EMBASE (1980-2011), and the CENTRAL (1977-2011) databases was searched for randomized controlled trials (RCTs). The relative risk (RR), mean difference (MD), and corresponding 95% confidence intervals (CIs) were calculated using RevMan 5 statistical software for dichotomous and continuous outcomes, respectively.
  
  
  RESULTS
  Of the 13 RCTs that met study inclusion criteria, 8 trials comprising 557 patients were analyzed. Leak pressure was higher in the PLMA (RR = 5.02, 95% CI = 3.64, 6.4). The difference in rate of successful placement on the first attempt did not differ between the two devices (RR = 1.00, 95% CI = 0.94, 1.06). The incidence of gastric insufflation was lower with the PLMA (RR = 0.20, 95% CI = 0.07, 0.61). The incidence of postoperative blood staining on the mask did not differ (RR = 1.08, 95% CI = 0.52, 2.21), nor was there any difference between the two devices in incidence of laryngospasm or bronchospasm (RR = 0.75, 95% CI = 0.18, 3.21), or hoarseness (RR = 3.00, 95% CI = 0.13, 70.83). There was no difference in laryngeal view between the PLMA and cLMA (RR = 1.06, 95% CI = 0.90, 1.26). The maximum tidal volume per kg was greater with the PLMA (MD = 4.16, 95% CI = 3.56, 4.76).
  
  
  CONCLUSIONS
  The PLMA (in sizes 1,1.5, 2, and 2.5) offers some advantages over the cLMA in pediatric anesthesia.
authors.affiliation: First School of Clinical Medicine, Nanjing Medical University, Nanjing, Jiangsu 210029, China.
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Zhang
authors.forename: Minghui
authors.initials: M
authors.lastname: Chen
authors.forename: Quan
authors.initials: Q
authors.lastname: Li
mesh_terms: D000758:Anesthesia / Q000379:methods*; D001801:Blood Stains; D001986:Bronchial Spasm / Q000453:epidemiology; D002648:Child; D004867:Equipment Design; D006685:Hoarseness / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D017214:Laryngeal Masks / Q000009:adverse effects; D007826:Laryngismus / Q000453:epidemiology; D016032:Randomized Controlled Trials as Topic; D013990:Tidal Volume