title: Reconstruction of the mandible bone by treatment of resected bone with pasteurization.
abstract: The results of long-term follow-up for reimplantation of the mandibular bone treated with pasteurization are reported. Mandibulectomy was performed for mandibular malignancy in 3 cases. The resected bones were subsequently reimplanted after treatment with pasteurization in 3 cases to eradicate tumor cells involved in the resected bone. Although postoperative infection was observed in 2 of 3 cases, reimplantation of the resected mandibular bone treated by pasteurization was finally successful. Ten to 22 years of follow-up was carried out. Pasteurization was able to devitalize tumor cells involved in the resected bone and to preserve bone-inductive activity. Reimplantation of pasteurization could be a useful strategy for reconstruction of the mandible in patients with mandibular malignancy.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Science, Kyushu Dental College, Kitakyushu, Fukuoka, Japan. r12uehara@fa.kyu-dent.ac.jp
authors.forename: Masataka
authors.initials: M
authors.lastname: Uehara
authors.forename: Tsugio
authors.initials: T
authors.lastname: Inokuchi
authors.forename: Kazuo
authors.initials: K
authors.lastname: Sano
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Sumita
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Tominaga
authors.forename: Izumi
authors.initials: I
authors.lastname: Asahina
mesh_terms: D000328:Adult; D001860:Bone Plates; D001863:Bone Screws; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D005260:Female; D005354:Fibrosarcoma / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008334:Mandible / Q000601:surgery*; D008339:Mandibular Neoplasms / Q000601:surgery*; D008875:Middle Aged; D061352:Pasteurization; D012092:Replantation / Q000379:methods*; D014025:Titanium; D016896:Treatment Outcome
chemical_list: D014025:Titanium