title: Antibacterial strategies from the sea: polymer-bound cl-catechols for prevention of biofilm formation.
abstract: Inspired by the amino acid 2-chloro-4,5-dihydroxyphenylalanine (Cl-DOPA), present in the composition of the proteinaceous glue of the sandcastle worm Phragmatopoma californica, a simple strategy is presented to confer antifouling properties to polymer surfaces using (but not releasing) a bioinspired biocide. Cl-Dopamine is used to functionalize polymer materials and hydrogel films easily, to prevent biofilm formation on them.
authors.affiliation: Max-Planck-Institut für Polymerforschung, Ackermannweg 10, 55128 Mainz, Germany.
authors.forename: Luis
authors.initials: L
authors.lastname: García-Fernández
authors.forename: Jiaxi
authors.initials: J
authors.lastname: Cui
authors.forename: Cristina
authors.initials: C
authors.lastname: Serrano
authors.forename: Zahid
authors.initials: Z
authors.lastname: Shafiq
authors.forename: Radu A
authors.initials: RA
authors.lastname: Gropeanu
authors.forename: Verónica San
authors.initials: VS
authors.lastname: Miguel
authors.forename: Jagoba Iturri
authors.initials: JI
authors.lastname: Ramos
authors.forename: Miao
authors.initials: M
authors.lastname: Wang
authors.forename: Gunther K
authors.initials: GK
authors.lastname: Auernhammer
authors.forename: Sandra
authors.initials: S
authors.lastname: Ritz
authors.forename: Ali A
authors.initials: AA
authors.lastname: Golriz
authors.forename: Rüdiger
authors.initials: R
authors.lastname: Berger
authors.forename: Manfred
authors.initials: M
authors.lastname: Wagner
authors.forename: Aránzazu
authors.initials: A
authors.lastname: del Campo
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D001422:Bacterial Adhesion / Q000187:drug effects; D018441:Biofilms / Q000187:drug effects*; D002396:Catechols / Q000737:chemistry*; D004295:Dihydroxyphenylalanine / Q000737:chemistry; D004926:Escherichia coli / Q000187:drug effects / Q000502:physiology; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000737:chemistry; D011077:Polychaeta / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D002396:Catechols; D011108:Polymers; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D004295:Dihydroxyphenylalanine