title: Interventional revisions of malfunctions affecting surgically implanted port-catheters for hepatic artery infusion.
abstract: OBJECTIVE
  Despite high response rates, feasibility of hepatic artery infusion (HAI) is impaired by frequent malfunctions of surgically implanted catheters (SIC). The aim of this study is to analyze the incidence and the types of malfunctions affecting the SIC and the success rate of interventional revisions (IR) in restoring patency to these catheters.
  
  
  METHODS
  In a single center, 101 consecutive patients treated with HAI through SIC over 10 years were retrospectively reviewed. The studied group (+IR) was composed of patients referred to interventional radiology for repair of catheter malfunctions. The overall patency of catheters in the +IR group was compared with the overall patency of a control group composed of patients without catheter malfunction (no IR).
  
  
  RESULTS
  86 patients were included with no difference in baseline characteristics between +IR (n = 40) and no IR (n = 46). There were no significant differences in overall patency between both groups (8.4 courses vs. 8.4 courses, p = 0.99). Furthermore, with an overall success rate of 72.5%, IR significantly improved the mean primary patency from 2.4 to 8.4 courses (p < 0.0001) in the +IR group.
  
  
  CONCLUSIONS
  By restoring a normal patency to SIC affected by different types of malfunctions, IR improves feasibility of HAI.
authors.affiliation: Department of Interventional Radiology, Institut Gustave Roussy, 39, rue Camille desmoulins, 94905 Villejuif, France. g.farouil@gmail.com
authors.forename: Geoffroy
authors.initials: G
authors.lastname: Farouil
authors.forename: Frederic
authors.initials: F
authors.lastname: Deschamps
authors.forename: Alireza
authors.initials: A
authors.lastname: Barah
authors.forename: Anne
authors.initials: A
authors.lastname: Auperin
authors.forename: Diane
authors.initials: D
authors.lastname: Goere
authors.forename: Dominique
authors.initials: D
authors.lastname: Elias
authors.forename: Thierry
authors.initials: T
authors.lastname: de Baere
mesh_terms: D000328:Adult; D000368:Aged; D002408:Catheters, Indwelling / Q000009:adverse effects*; D015179:Colorectal Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006499:Hepatic Artery / Q000601:surgery*; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000009:adverse effects*; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011379:Prognosis; D012086:Reoperation; D012189:Retrospective Studies; D062666:Vascular Access Devices / Q000009:adverse effects*