title: First detection of oqxAB in Salmonella spp. isolated from food.
abstract: Food-borne salmonellosis is an important public health problem worldwide and the second leading cause of food-borne illnesses in Hong Kong. In this study, the prevalence and antimicrobial resistance of Salmonella in meat products in Hong Kong were determined. Interestingly, a plasmid-mediated quinolone resistance (PMQR) gene combination, oqxAB, which mediates resistance to nalidixic acid, chloramphenicol, and olaquindox, was for the first time detectable on the chromosomes of two Salmonella enterica serovar Derby isolates. Further surveillance of oqxAB in Salmonella will be needed.
authors.affiliation: Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR.
authors.forename: Marcus Ho Yin
authors.initials: MH
authors.lastname: Wong
authors.forename: Sheng
authors.initials: S
authors.lastname: Chen
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D002701:Chloramphenicol / Q000494:pharmacology / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D005516:Food Microbiology; D005798:Genes, Bacterial; D006723:Hong Kong; D006801:Humans; D008461:Meat Products / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D009268:Nalidixic Acid / Q000494:pharmacology / Q000627:therapeutic use; D010957:Plasmids; D011810:Quinoxalines / Q000494:pharmacology / Q000627:therapeutic use; D012478:Salmonella Food Poisoning / Q000188:drug therapy / Q000382:microbiology; D012480:Salmonella Infections / Q000188:drug therapy / Q000382:microbiology; D019779:Salmonella enterica / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D012703:Serotyping
chemical_list: D000900:Anti-Bacterial Agents; D011810:Quinoxalines; D009268:Nalidixic Acid; D002701:Chloramphenicol; C013168:olaquindox