title: Circulating natriuretic peptide concentrations in hyperthyroid cats.
abstract: OBJECTIVE
  To assess the influence of thyroid function on natriuretic peptide concentration in hyperthyroid cats before and after treatment.
  
  
  METHODS
  Serum natriuretic peptide concentration was measured in 61 hyperthyroid cats recruited from first-opinion clinics before and after treatment.
  
  
  RESULTS
  Following successful treatment, total thyroxine, heart rate, systolic blood pressure and packed cell volume all decreased and bodyweight and creatinine concentrations increased. Furthermore, a significant (P < 0·001) decline in NT-proBNP concentration but not NT-proANP was identified.
  
  
  CONCLUSIONS
  Thyroid function has a modest but significant effect on NT-proBNP concentration. Thyroid status should be taken into account when interpreting NT-proBNP concentrations in cats.
authors.affiliation: Department of Veterinary Clinical Sciences, The Royal Veterinary College, North Mymms, Hertfordshire, UK.
authors.forename: P
authors.initials: P
authors.lastname: Menaut
authors.forename: D J
authors.initials: DJ
authors.lastname: Connolly
authors.forename: A
authors.initials: A
authors.lastname: Volk
authors.forename: C
authors.initials: C
authors.lastname: Pace
authors.forename: V
authors.initials: V
authors.lastname: Luis Fuentes
authors.forename: J
authors.initials: J
authors.lastname: Elliott
authors.forename: H
authors.initials: H
authors.lastname: Syme
mesh_terms: D000818:Animals; D013956:Antithyroid Agents / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure / Q000502:physiology; D016022:Case-Control Studies; D002371:Cat Diseases / Q000097:blood* / Q000188:drug therapy; D002415:Cats / Q000097:blood*; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006980:Hyperthyroidism / Q000097:blood / Q000188:drug therapy / Q000662:veterinary*; D008297:Male; D008713:Methimazole / Q000627:therapeutic use; D020097:Natriuretic Peptide, Brain / Q000097:blood; D045265:Natriuretic Peptides / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood; D013974:Thyroxine / Q000097:blood; D016896:Treatment Outcome
chemical_list: D013956:Antithyroid Agents; D015415:Biomarkers; D045265:Natriuretic Peptides; D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain; D008713:Methimazole; D013974:Thyroxine