title: Developmental changes and effect on intramuscular fat content of H-FABP and A-FABP mRNA expression in pigs.
abstract: H-FABP and A-FABP genes are considered as candidates for intramuscular fat (IMF) accretion. The aim of the present study was to assess the expression of H-FABP and A-FABP genes in m. longissimus dorsi (LD) and liver tissues of Laiwu and Lulai Black pig populations of different body weight (BW). Eighty-four barrows at different BW (30, 40, 50, 60, 70, 80, 90 and 100 kg, n = 6 per group) of Laiwu Black pig (no 100 kg group) and Lulai Black pig (no 30 kg group) were used to study the development changes of A-FABP and H-FABP mRNA expression and their relationships to IMF content. The results showed that, in both breeds, the IMF content increased continuously with growing (P < 0.05). The expression of H-FABP and A-FABP genes also increased with growing in LD tissue (P < 0.05), and reached a peak at 50 and 70 kg BW in Laiwu and Lulai Black pig, respectively. However, this regularity was not observed in liver tissue in both breeds. A positive correlation was just found between the A-FABP mRNA expression level in LD tissue and IMF content and BW in both breeds (P < 0.05). In conclusion, the A-FABP gene is strongly related to the development and function of IMF accretion in pigs.
authors.affiliation: College of Animal Science and Technology, Shandong Agricultural University, 61 Daizong Street, Tai'an, 271018, People's Republic of China.
authors.forename: Qi-Mei
authors.initials: QM
authors.lastname: Chen
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.forename: Yong-Qing
authors.initials: YQ
authors.lastname: Zeng
authors.forename: Wei
authors.initials: W
authors.lastname: Chen
mesh_terms: D017667:Adipocytes / Q000378:metabolism; D000273:Adipose Tissue / Q000033:anatomy & histology*; D000818:Animals; D001835:Body Weight / Q000235:genetics; D050556:Fatty Acid-Binding Proteins / Q000235:genetics*; D015870:Gene Expression; D005838:Genotype; D008460:Meat / Q000032:analysis; D018482:Muscle, Skeletal / Q000033:anatomy & histology / Q000254:growth & development* / Q000378:metabolism*; D012333:RNA, Messenger / Q000096:biosynthesis; D034421:Sus scrofa / Q000033:anatomy & histology / Q000235:genetics* / Q000254:growth & development
chemical_list: D050556:Fatty Acid-Binding Proteins; D012333:RNA, Messenger