title: Palladacycle-catalyzed reaction of bicyclic alkenes with terminal ynones: regiospecific synthesis of polysubstituted furans.
abstract: A new synthetic strategy to access polysubstituted furans regiospecifically has been developed using simple bicyclic alkenes and terminal ynones as starting materials with palladacycles as unique active catalysts. A rational mechanism has also been proposed. This reaction features mild reaction conditions, easily available starting materials and palladacycle catalysts, a wide substrate scope, and high regiospecificity.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 345 Ling Ling Road, Shanghai 200032, China.
authors.forename: Guang-Cun
authors.initials: GC
authors.lastname: Ge
authors.forename: Dong-Liang
authors.initials: DL
authors.lastname: Mo
authors.forename: Chang-Hua
authors.initials: CH
authors.lastname: Ding
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Dai
authors.forename: Xue-Long
authors.initials: XL
authors.lastname: Hou
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D005663:Furans; D007659:Ketones; D010165:Palladium