title: Diffusion weighted imaging and contrast-enhanced magnetic resonance imaging in the evaluation of early stage endometrial cancer.
abstract: OBJECTIVE
  To assess the values of diffusion weighted imaging and contrast-enhanced magnetic resonance imaging (MRI) in the evaluation of early endometrial cancer.
  
  
  METHODS
  We retrospectively analyzed the imaging data of 27 patients with pathologically confirmed stage 1-2 endometrial cancer. These patients received pelvic magnetic resonance imaging, diffusion weighted imaging with apparent diffusion coefficient-T2 weighted imaging fusion images(ADC-T2WI), and T1 weighted imaging (T1WI) of contrast-enhanced scan sequence. The accuracies of these image modes were analyzed and compared.
  
  
  RESULTS
  The accuracy of routine pelvic MRI scan, diffusion weighted imaging with ADC-T2WI fusion images, and T1WI of contrast-enhanced scan for the early diagnosis of endometrial cancer was 66.7%, 85.2%, and 92.5%, respectively. The sensitivity, specificity and diagnostic accuracy of diffusion weighted imaging with ADC-T2WI fusion images in the diagnosis of lesions with a 1/2 depth of muscle were 82.3%, 75%, and 85.2%.
  
  
  CONCLUSIONS
  Routine pelvic MRI scan sequence has certain errors for the early diagnosis of endometrial cancer. On the contrary, the diffusion weighted imaging with ADC-T2WI image fusion has remarkably increased diagnostic accuracy. The T1WI of contrast-enhanced scan can clearly display most of the lesions by identifying the muscular infiltrations, and therefore can provide the most accurate information for the staging of early endometrial cancer.
authors.affiliation: Department of Radiology, Fourth People's Hospital of Shenyang City, Shenyang 110031, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: An
authors.forename: Jing
authors.initials: J
authors.lastname: Ynag
authors.forename: Yue
authors.initials: Y
authors.lastname: Zhu
mesh_terms: D000328:Adult; D000368:Aged; D003287:Contrast Media; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media