title: Determination of the quenching correction factors for plastic scintillation detectors in therapeutic high-energy proton beams.
abstract: Plastic scintillation detectors (PSDs) have many advantages over other detectors in small field dosimetry due to their high spatial resolution, excellent water equivalence and instantaneous readout. However, in proton beams, the PSDs undergo a quenching effect which makes the signal level reduced significantly when the detector is close to the Bragg peak where the linear energy transfer (LET) for protons is very high. This study measures the quenching correction factor (QCF) for a PSD in clinical passive-scattering proton beams and investigates the feasibility of using PSDs in depth-dose measurements in proton beams. A polystyrene-based PSD (BCF-12, ϕ0.5 mm × 4 mm) was used to measure the depth-dose curves in a water phantom for monoenergetic unmodulated proton beams of nominal energies 100, 180 and 250 MeV. A Markus plane-parallel ion chamber was also used to get the dose distributions for the same proton beams. From these results, the QCF as a function of depth was derived for these proton beams. Next, the LET depth distributions for these proton beams were calculated by using the MCNPX Monte Carlo code, based on the experimentally validated nozzle models for these passive-scattering proton beams. Then the relationship between the QCF and the proton LET could be derived as an empirical formula. Finally, the obtained empirical formula was applied to the PSD measurements to get the corrected depth-dose curves and they were compared to the ion chamber measurements. A linear relationship between the QCF and LET, i.e. Birks' formula, was obtained for the proton beams studied. The result is in agreement with the literature. The PSD measurements after the quenching corrections agree with ion chamber measurements within 5%. PSDs are good dosimeters for proton beam measurement if the quenching effect is corrected appropriately.
authors.affiliation: Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
authors.forename: L L W
authors.initials: LL
authors.lastname: Wang
authors.forename: L A
authors.initials: LA
authors.lastname: Perles
authors.forename: L
authors.initials: L
authors.lastname: Archambault
authors.forename: N
authors.initials: N
authors.lastname: Sahoo
authors.forename: D
authors.initials: D
authors.lastname: Mirkovic
authors.forename: S
authors.initials: S
authors.lastname: Beddar
mesh_terms: D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D011137:Polystyrenes; D061766:Proton Therapy; D011879:Radiotherapy Dosage; D012542:Scattering, Radiation; D012588:Scintillation Counting / Q000379:methods*; D014867:Water
chemical_list: D011137:Polystyrenes; D014867:Water