title: Clinical significance of ptyalism gravidarum.
abstract: OBJECTIVE
  The aim of this study was to identify the clinical significance associated with ptyalism gravidarum in Japanese singleton pregnancies.
  
  
  METHODS
  Data were collected from 22 patients complicated by ptyalism gravidarum whose symptoms continued until delivery and from 7,743 unaffected controls.
  
  
  RESULTS
  The incidence of ptyalism gravidarum in the Japanese pregnant women was about 0.3 %. Using multiple logistic regressions, ptyalism gravidarum was associated with history of hyperemesis gravidarum (p < 0.01), neonatal male sex (p = 0.02) and small for gestational age infants (p = 0.04).
  
  
  CONCLUSIONS
  Ptyalism gravidarum may be a distinctive condition leading to adverse perinatal outcomes.
authors.affiliation: Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, 5-11-12 Tateishi, Katsushika-ku, Tokyo 124-0012, Japan. czg83542@mopera.ne.jp
authors.forename: Shunji
authors.initials: S
authors.lastname: Suzuki
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Fuse
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D007564:Japan / Q000453:epidemiology; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D012798:Sialorrhea / Q000453:epidemiology*