title: Giant dacryocystocele and congenital alacrimia in lacrimo-auriculo-dento-digital syndrome.
abstract: The lacrimo-auriculo-dento-digital syndrome, also known as Levy-Hollister syndrome, is a rare multiple congenital dysplasia characterized by malformation of the lacrimal apparatus and by aural, dental, and digital anomalies. Since the first report in 1973, different clinical findings such as urogenital malformations and facial dysmorphism have been described in the affected patients, showing that the phenotypic spectrum of the syndrome is broad. The authors report for the first time an association among giant dacryocystocele, alacrima, and agenesis of the lacrimal puncta in a patient with lacrimo-auriculo-dento-digital syndrome.
authors.affiliation: Department of Ophthalmology, Otorhinolaryngology, and Head and Neck Surgery, School of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, Brazil.
authors.forename: Rodrigo O Espirito
authors.initials: RO
authors.lastname: Santo
authors.forename: Marcelo B
authors.initials: MB
authors.lastname: Golbert
authors.forename: Patricia M S
authors.initials: PM
authors.lastname: Akaishi
authors.forename: Antonio A V
authors.initials: AA
authors.lastname: Cruz
authors.forename: Murilo B
authors.initials: MB
authors.lastname: Cintra
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis; D000293:Adolescent; D015785:Eye Diseases, Hereditary / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D034381:Hearing Loss / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000150:complications / Q000175:diagnosis / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D009078:Mucocele / Q000175:diagnosis / Q000209:etiology*; D009301:Nasolacrimal Duct / Q000000981:diagnostic imaging / Q000473:pathology; D013576:Syndactyly / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D014071:Tooth Abnormalities / Q000150:complications* / Q000175:diagnosis