title: Socioeconomic deprivation and associated risk factors of traumatic brain injury in children.
abstract: BACKGROUND
  This study aimed to investigate the relative risks of low income (family socioeconomic deprivation) and associated factors for traumatic brain injury (TBI) in children.
  
  
  METHODS
  Using Taiwan National Health Insurance Research Database and adjusting the covariates, we conducted a population-based case-control study analyzing 8,291 pediatric patients, aged 0 year to 17 years, diagnosed with TBI, and 33,164 sex- and age-matched controls to study the association of low income and TBI. The relative risks of TBI for socioeconomically deprived children with various coexisted medical conditions were evaluated.
  
  
  RESULTS
  After adjustment, pediatric population with low income were at increased risk of TBI (odds ratio [OR], 1.71; 95% confidence interval [CI], 1.52-1.92). Among the coexisting medical conditions, low-income pediatric population with mental disorders had significantly increased TBI risk when compared with matched controls (adjusted OR, 1.99; 95% CI, 1.51-2.63). Increased risk of TBI was also found in low-income children with epilepsy when compared with children of regular family income (adjusted OR, 3.11; 95% CI, 1.65-5.86). The adjusted OR of TBI for low-income children with mental disorders and epilepsy was as high as 4.45 (95% CI, 1.96-10.1). Among TBI patients, low-income children who had epilepsy were at significantly higher risk of post-TBI intracranial hemorrhage when compared with controls (OR, 10.6; 95% CI, 3.30-33.9).
  
  
  CONCLUSIONS
  We found a significantly increased risk of TBI in socioeconomically deprived children, particularly among children with mental disorders, epilepsy, or both. Low-income children should be considered for special attention to reduce TBI risk and post-TBI morbidities.
  
  
  METHODS
  Prognostic study, level III.
authors.affiliation: Department of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan.
authors.forename: Chien-Chang
authors.initials: CC
authors.lastname: Liao
authors.forename: Huai-Chia
authors.initials: HC
authors.lastname: Chang
authors.forename: Chun-Chieh
authors.initials: CC
authors.lastname: Yeh
authors.forename: Yi-Chun
authors.initials: YC
authors.lastname: Chou
authors.forename: Wen-Ta
authors.initials: WT
authors.lastname: Chiu
authors.forename: Ta-Liang
authors.initials: TL
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D001930:Brain Injuries / Q000150:complications / Q000453:epidemiology*; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000150:complications; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D001523:Mental Disorders / Q000150:complications; D011203:Poverty; D012307:Risk Factors; D012923:Social Class; D013624:Taiwan / Q000453:epidemiology