title: Ototoxicity in dogs and cats.
abstract: A variety of drugs in veterinary use have side effects that can potentially damage the senses of hearing or balance in animals. A large body of literature exists on the incidence and mechanisms of ototoxicity in experimental animals and in humans, but little is documented in domestic dogs and cats. However, the generality of these adverse actions across species allows one to extrapolate and provide the veterinarian with insight into possible complications of chemotherapy.
authors.affiliation: Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan Medical School, Ann Arbor, MI 48109-5616, USA.
authors.forename: Naoki
authors.initials: N
authors.lastname: Oishi
authors.forename: Andra E
authors.initials: AE
authors.lastname: Talaska
authors.forename: Jochen
authors.initials: J
authors.lastname: Schacht
mesh_terms: D000617:Aminoglycosides / Q000009:adverse effects / Q000627:therapeutic use; D000818:Animals; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D002371:Cat Diseases / Q000139:chemically induced* / Q000517:prevention & control; D002415:Cats; D002945:Cisplatin / Q000009:adverse effects / Q000627:therapeutic use; D004283:Dog Diseases / Q000139:chemically induced* / Q000517:prevention & control; D004285:Dogs; D004358:Drug Therapy / Q000662:veterinary*; D064420:Drug-Related Side Effects and Adverse Reactions; D006311:Hearing Disorders / Q000139:chemically induced / Q000517:prevention & control / Q000662:veterinary*
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D002945:Cisplatin