title: Current guidelines for total joint VTE prophylaxis: dawn of a new day.
abstract: Venous thromboembolism (VTE) remains an immediate   threat to patients following total hip and knee replacement. While   there is a strong consensus that steps should be taken to minimise   the risk to patients by utilising some forms of prophylaxis for   the vast majority of patients, the methods utilised have been extremely   variable. Clinical practice guidelines (CPGs) have been published   by various professional organisations for over 25 years to provide recommendations   to standardise VTE prophylaxis. Historically, these recommendations   have varied widely depending in underlying assumptions, goals, and   methodology of the various groups. This effort has previously been   exemplified by the American College of Chest Physicians (ACCP) and   the American Academy of Orthopaedic Surgeons (AAOS). The former   group of medical specialists targeted minimising venographically   proven deep vein thrombosis (DVT) (the vast majority of which are   asymptomatic) as their primary goal prior to 2012. The latter group of   surgeons targeted minimising symptomatic VTE. As a result prior   to 2012, the recommendations of the two groups were widely divergent.   In the past year, both groups have reassessed the current literature   with the principal goals of minimising symptomatic VTE events and   bleeding complications. As a result, for the first time the CPGs   of these two major subspecialty organisations are in close agreement.
authors.affiliation: Department of Orthopaedic Surgery, Washington University School of Medicine, One Barnes-Jewish Hospital Plaza, 11300 West Pavilion, Campus Box 8233, St Louis, Missouri 63110, USA. barrackr@wustl.edu
authors.forename: R L
authors.initials: RL
authors.lastname: Barrack
mesh_terms: D019644:Arthroplasty, Replacement, Hip; D019645:Arthroplasty, Replacement, Knee; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D011183:Postoperative Complications / Q000175:diagnosis / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D011300:Preoperative Care / Q000379:methods* / Q000592:standards; D018570:Risk Assessment; D012955:Societies, Medical; D014481:United States; D054556:Venous Thromboembolism / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D020246:Venous Thrombosis / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control
chemical_list: D005343:Fibrinolytic Agents