title: Primary leiomyosarcoma of the breast: A case report and review of literature.
abstract: Leiomyosarcomas of the breast are rare tumours. Only 18 such cases have been reported in the literature so far. We describe herein a case of primary leiomyosarcoma of the breast in a 54-year-old woman whose preoperative clinical and cytological findings indicated a benign breast tumour. However, a core needle biopsy of the lesion showed malignant spindle cells without any ductal elements. Histopathological examination of the mastectomy specimen suggested a diagnosis of leiomyosarcoma, which was subsequently confirmed by immunohistochemical analysis. Primary leiomyosarcoma of the breast is very rare and is difficult to diagnose preoperatively as it needs immuno-histochemical staining. It is necessary to excise the tumour with sufficient margins to prevent local recurrence. The role of postoperative adjuvant chemotherapy is not well documented.
authors.affiliation: Departments of Surgery and Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, 605 006 India.
authors.forename: B
authors.initials: B
authors.lastname: Sandhya
authors.forename: Vivek
authors.initials: V
authors.lastname: Babu
authors.forename: G
authors.initials: G
authors.lastname: Parthasarathy
authors.forename: Vikram
authors.initials: V
authors.lastname: Kate
authors.forename: N
authors.initials: N
authors.lastname: Ananthakrishnan
authors.forename: R
authors.initials: R
authors.lastname: Krishnan
keywords: Breast; Phyllodes Sandhya; Stromal tumours