title: The effect of Kombucha on post-operative intra-abdominal adhesion formation in rats.
abstract: BACKGROUND
  Peritoneal adhesions are fibrous bands of tissues formed between organs that are normally separated and/or between organs and the internal body wall after peritoneal injury. The aim of the study was to investigate the effect of intra-peritoneal administration of Kombucha on intra-peritoneal adhesions.
  
  
  METHODS
  Eighty Wistar rats were subjected to standardized lesion by scraping model and were randomly divided into two groups. Group I received no treatment, and Group II received 15 ml of Kombucha solution intra-peritoneally. On the post-operative 14th day adhesion intensity score, inflammatory cell reaction and number of adhesion bands were determined.
  
  
  RESULTS
  In the control group, there were no rats with grade 0 and I adhesions. In the group II, there were 26 rats (78.8%) with grade 0-2 adhesions. Adhesion intensity was significantly less in group II (P<0.0001). Number of adhesion bands was significantly less in group II (P<0.001).
  
  
  CONCLUSIONS
  It was concluded that intra-peritoneal administration of Kombucha might be useful for preventing peritoneal adhesions.
authors.affiliation: Department of Surgery, Faculty of Medicine, University of Medical Sciences of Tabriz, Tabriz, Iran.
authors.forename: Hemmat
authors.initials: H
authors.lastname: Maghsoudi
authors.forename: Hussein Benagozar
authors.initials: HB
authors.lastname: Mohammadi
keywords: Kombucha; Peritoneal adhesions; Prevention