title: Glucan from hot aqueous extract of an ectomycorrhizal edible mushroom, Russula albonigra (Krombh.) Fr.: structural characterization and study of immunoenhancing properties.
abstract: A water soluble glucan (PS-I) was isolated from the hot aqueous extract of the fruit bodies of an ectomycorrhizal edible mushroom, Russula albonigra (Krombh.) Fr. The total hydrolysis, methylation analysis, periodate oxidation, and NMR ((1)H, (13)C, DEPT-135, TOCSY, DQF-COSY, NOESY, ROESY, HSQC, and HMBC) studies revealed the presence of the following repeating unit in the polysaccharide: This glucan showed excellent activation of macrophages as well as splenocytes and thymocytes in vitro.
authors.affiliation: Department of Chemistry & Chemical Technology, Vidyasagar University, Midnapore 721102, West Bengal, India.
authors.forename: Ashis K
authors.initials: AK
authors.lastname: Nandi
authors.forename: Ipsita K
authors.initials: IK
authors.lastname: Sen
authors.forename: Surajit
authors.initials: S
authors.lastname: Samanta
authors.forename: Kousik
authors.initials: K
authors.lastname: Maity
authors.forename: K Sanjana P
authors.initials: KS
authors.lastname: Devi
authors.forename: Shreemoyee
authors.initials: S
authors.lastname: Mukherjee
authors.forename: Tapas K
authors.initials: TK
authors.lastname: Maiti
authors.forename: Krishnendu
authors.initials: K
authors.lastname: Acharya
authors.forename: Syed S
authors.initials: SS
authors.lastname: Islam
mesh_terms: D000363:Agaricales / Q000737:chemistry*; D000818:Animals; D002240:Carbohydrate Sequence; D002460:Cell Line; D048690:Fruiting Bodies, Fungal / Q000737:chemistry; D005936:Glucans / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D006367:HeLa Cells; D006358:Hot Temperature; D006801:Humans; D007155:Immunologic Factors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D008264:Macrophages / Q000187:drug effects / Q000276:immunology; D051379:Mice; D008969:Molecular Sequence Data; D038821:Mycorrhizae / Q000737:chemistry*; D012995:Solubility; D014867:Water / Q000737:chemistry*
chemical_list: D005936:Glucans; D007155:Immunologic Factors; D014867:Water