title: Detecting and managing hereditary colorectal cancer syndromes in your practice.
abstract: Hereditary syndromes account for 5% to 10% of cases of colorectal cancer. In clinical practice, patients with these syndromes need to be identified to ensure that they and their families receive genetic counseling and testing and appropriate risk-reducing treatment. Genetic testing can offer a precise diagnosis. It allows for risk stratification and focused management and surveillance.
authors.affiliation: Genomic Medicine Institute, Taussig Cancer Institute, The Sanford R. Weiss Center for Inherited Colorectal Neoplasia, Cleveland Clinic, Cleveland, OH 44195, USA. leachb@ccf.org
authors.forename: Brandie
authors.initials: B
authors.lastname: Heald
authors.forename: James
authors.initials: J
authors.lastname: Church
authors.forename: Thomas
authors.initials: T
authors.lastname: Plesec
authors.forename: Carol A
authors.initials: CA
authors.lastname: Burke
mesh_terms: D000236:Adenoma / Q000175:diagnosis; D011125:Adenomatous Polyposis Coli / Q000175:diagnosis / Q000235:genetics / Q000517:prevention & control / Q000628:therapy; D017668:Age of Onset; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000175:diagnosis / Q000235:genetics / Q000517:prevention & control / Q000628:therapy; D005192:Family Health; D005817:Genetic Counseling / Q000379:methods / Q000592:standards*; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing / Q000592:standards*; D006801:Humans