title: Cardio-metabolic features of type 2 diabetes subjects discordant in the diagnosis of metabolic syndrome.
abstract: BACKGROUND
  The aim of this study is to investigate the cardio-metabolic parameters and surrogate markers of insulin resistance in a discordant group of type 2 diabetes (T2DM) subjects who satisfy the Adults Treatment Panel (ATP) III criteria, but not the International Diabetes Federation (IDF) criteria, for metabolic syndrome (MetS).
  
  
  METHODS
  We assessed the prevalence of MetS in T2DM subjects (n=167) who were selected from subjects registered at the diabetes center of Dong-A University Medical Center. We used the ATP III criteria and the IDF criteria for the diagnosis of MetS and sorted the subjects into 2 MetS groups: one group diagnosed per ATP III criteria (MetSa) and one diagnosed per IDF criteria (MetSi). We then compared the clinical characteristics, metabolic parameters (homeostasis model assessment of insulin resistance, aspartate aminotransferase, alanine aminotransferase, and uric acid values) and co-morbidities (prevalence of microalbuminuria, fatty liver, and cardiovascular disease) between the MetSa, MetSi, and discordant MetS groups.
  
  
  RESULTS
  The prevalence of MetS in the MetSa group (73.6%) was higher than in the MetSi group (62.2%). The MetS prevalence in the discordant group was 11.4%. The discordant group showed no significant differences in clinical characteristics (except waist circumference and body mass index), metabolic parameters, or prevalence of co-morbidities, as compared with subjects with MetS by both criteria.
  
  
  CONCLUSIONS
  In this study, cardio-metabolic features of the subjects diagnosed with MetS using ATP III criteria, but not IDF criteria, are not significantly different from those of subjects diagnosed with MetS using both criteria.
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Sevrance-Uva Surgical Hospital, Busan, Korea.
authors.forename: Sa Rah
authors.initials: SR
authors.lastname: Lee
authors.forename: Ying
authors.initials: Y
authors.lastname: Han
authors.forename: Ja Won
authors.initials: JW
authors.lastname: Kim
authors.forename: Ja Young
authors.initials: JY
authors.lastname: Park
authors.forename: Ji Min
authors.initials: JM
authors.lastname: Kim
authors.forename: Sunghwan
authors.initials: S
authors.lastname: Suh
authors.forename: Mi-Kyoung
authors.initials: MK
authors.lastname: Park
authors.forename: Hye-Jeong
authors.initials: HJ
authors.lastname: Lee
authors.forename: Duk Kyu
authors.initials: DK
authors.lastname: Kim
keywords: Diabetes mellitus; Discordant group; Metabolic syndrome; Waist circumference