title: The hypertriglyceridemic waist, waist-to-height ratio, and cardiometabolic risk.
abstract: OBJECTIVE
  To investigate whether the hypertriglyceridemic waist (HW) phenotype and waist-to-height ratio (WHTR) are associated with cardiometabolic disorders in children and adolescents.
  
  
  METHODS
  This was a cross-sectional design study. Anthropometry, biochemical variables, and cardiorespiratory fitness were assessed in 234 participants (122 girls) aged 10-19 years from Bedfordshire, United Kingdom. The HW phenotype was defined as a waist circumference ≥90(th) percentile for age and sex, and triglyceride concentrations ≥1.24 mmol/L, and a high WHTR defined as >0.5. ANCOVA and logistic regression were used in the analysis.
  
  
  RESULTS
  In participants with the HW phenotype, the odds of having high cardiorespiratory fitness (mL/kg/min) were lower (0.045; 95% CI 0.01, 0.42), and the odds of having low high-density lipoprotein cholesterol (4.41; 1.50, 12.91), impaired fasting glucose (3.37; 1.06, 10.72), and ≥1 (4.78; 1.32, 17.29) and ≥2 risk factors (7.16; 2.38, 21.54) were higher than those without the phenotype. Those with a high WHTR had higher odds of having low high-density lipoprotein cholesterol (2.57; 1.11, 5.95), high diastolic blood pressure (3.21; 1.25, 8.25), and ≥2 risk factors (5.57; 2.05, 15.17) than those with normal WHTR.
  
  
  CONCLUSIONS
  The HW phenotype may be a better simple marker than WHTR for identifying children and adolescents at risk for cardiometabolic disorders.
authors.affiliation: Department of Sport and Exercise Sciences, Institute for Sport and Physical Activity Research, University of Bedfordshire, Bedford, Bedfordshire, United Kingdom. daniel.bailey@beds.ac.uk
authors.forename: Daniel P
authors.initials: DP
authors.lastname: Bailey
authors.forename: Louise A
authors.initials: LA
authors.lastname: Savory
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: Denton
authors.forename: Ben R
authors.initials: BR
authors.lastname: Davies
authors.forename: Catherine J
authors.initials: CJ
authors.lastname: Kerr
mesh_terms: D000293:Adolescent; D000886:Anthropometry / Q000379:methods; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000175:diagnosis*; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D015228:Hypertriglyceridemia / Q000175:diagnosis* / Q000503:physiopathology*; D008297:Male; D015999:Multivariate Analysis; D016017:Odds Ratio; D010641:Phenotype; D012306:Risk; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood; D006113:United Kingdom; D055105:Waist Circumference
chemical_list: D014280:Triglycerides