title: Three-dimensional knee moments of ACL reconstructed and control subjects during gait, stair ascent, and stair descent.
abstract: Changes in knee mechanics following anterior cruciate ligament reconstruction (ACLR) have been implicated as a contributor to the development of premature osteoarthritis (OA). However, changes in ambulatory loading in this population have not been well documented. While the magnitude of the external knee moment vector is a major factor in loading at the knee, there is not a comprehensive understanding of the changes in the individual components of the vector following ACL reconstruction. The purpose of this study was to test for differences in the three components of the external knee moment during walking and stair locomotion between ACLR, contralateral and healthy control knees. Forty-five ACLR and 45 healthy control subjects were tested during walking, stair ascent and descent. ACLR knees had a lower first peak adduction moment than contralateral knees during all three activities. Similarly, additional cases of significant differences between ACLR and contralateral knees consisted of lower peak moments for the ACLR than the contralateral knees. These differences were due to both ACLR and contralateral knees as the ACLR knees indicated lower and the contralateral knees greater peak moments compared to healthy control knees. The results suggest a compensatory change involving greater loading in the contralateral knee, perhaps due to lower loading of the ACLR knee. Further, lower knee moments of the ACLR knee suggest that increased joint loading may not be the initiating factor in the development of OA following ACL reconstruction; but rather previous described kinematic or biological changes might initiate the pathway to knee OA.
authors.affiliation: Department of Mechanical Engineering, Stanford University, Stanford, CA, USA. mezabala@stanford.edu
authors.forename: Michael E
authors.initials: ME
authors.lastname: Zabala
authors.forename: Julien
authors.initials: J
authors.lastname: Favre
authors.forename: Sean F
authors.initials: SF
authors.lastname: Scanlan
authors.forename: Joseph
authors.initials: J
authors.lastname: Donahue
authors.forename: Thomas P
authors.initials: TP
authors.lastname: Andriacchi
mesh_terms: D000328:Adult; D059549:Anterior Cruciate Ligament Reconstruction; D005260:Female; D005684:Gait; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology*; D008297:Male; D020370:Osteoarthritis, Knee / Q000209:etiology / Q000503:physiopathology; D016138:Walking; D016474:Weight-Bearing