title: Identification of a novel human leukocyte antigen allele B∗46:34.
abstract: A new human leukocyte antigen (HLA) B allele was found in a healthy male Chinese Kazak individual. Sequencing-based typing (SBT) was used to identify and analyze the difference between the new allele and the closest matching HLA-B allele. HLA-B(∗)46 new allele has 1nt change from B(∗)46:01:01 at nt 853 where G->C (condon 260 GTA->CTA), resulting in a coding change: 260 Val is changed to Leu. The new HLA-B(∗)46:34 allele was identified, and was named officially by the World Health Organization (WHO) Nomenclature Committee in June 2012. The GenBank sequence accession number is JX035785.
authors.affiliation: School of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, PR China.
authors.forename: Chun-mei
authors.initials: CM
authors.lastname: Shen
authors.forename: Hong-dan
authors.initials: HD
authors.lastname: Wang
authors.forename: Ya-jun
authors.initials: YJ
authors.lastname: Deng
authors.forename: Shi-ying
authors.initials: SY
authors.lastname: Wang
authors.forename: Li-ping
authors.initials: LP
authors.lastname: Zhang
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.forename: Hong-wei
authors.initials: HW
authors.lastname: Pu
authors.forename: Qiang-ju
authors.initials: QJ
authors.lastname: Wu
authors.forename: Wen-juan
authors.initials: WJ
authors.lastname: Liu
authors.forename: Bo-feng
authors.initials: BF
authors.lastname: Zhu
mesh_terms: D000483:Alleles; D015235:HLA-B Antigens / Q000235:genetics*; D006650:Histocompatibility Testing; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D055815:Young Adult
chemical_list: D015235:HLA-B Antigens