title: Rfam 11.0: 10 years of RNA families.
abstract: The Rfam database (available via the website at http://rfam.sanger.ac.uk and through our mirror at http://rfam.janelia.org) is a collection of non-coding RNA families, primarily RNAs with a conserved RNA secondary structure, including both RNA genes and mRNA cis-regulatory elements. Each family is represented by a multiple sequence alignment, predicted secondary structure and covariance model. Here we discuss updates to the database in the latest release, Rfam 11.0, including the introduction of genome-based alignments for large families, the introduction of the Rfam Biomart as well as other user interface improvements. Rfam is available under the Creative Commons Zero license.
authors.affiliation: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK. sb30@sanger.ac.uk
authors.forename: Sarah W
authors.initials: SW
authors.lastname: Burge
authors.forename: Jennifer
authors.initials: J
authors.lastname: Daub
authors.forename: Ruth
authors.initials: R
authors.lastname: Eberhardt
authors.forename: John
authors.initials: J
authors.lastname: Tate
authors.forename: Lars
authors.initials: L
authors.lastname: Barquist
authors.forename: Eric P
authors.initials: EP
authors.lastname: Nawrocki
authors.forename: Sean R
authors.initials: SR
authors.lastname: Eddy
authors.forename: Paul P
authors.initials: PP
authors.lastname: Gardner
authors.forename: Alex
authors.initials: A
authors.lastname: Bateman
mesh_terms: D001483:Base Sequence; D030561:Databases, Nucleic Acid; D023281:Genomics; D020407:Internet; D058977:Molecular Sequence Annotation; D009690:Nucleic Acid Conformation; D022661:RNA, Untranslated / Q000737:chemistry* / Q000145:classification* / Q000235:genetics; D016415:Sequence Alignment; D014584:User-Computer Interface
chemical_list: D022661:RNA, Untranslated