title: Cyclometalated iridium(III) polypyridine dibenzocyclooctyne complexes as the first phosphorescent bioorthogonal probes.
abstract: We report the synthesis, photophysical behavior, and biological properties of new cyclometalated iridium(iii) polypyridine complexes appended with a dibenzocyclooctyne (DIBO) moiety; these complexes have been utilized as the first phosphorescent bioorthogonal probes for azide-modified biomolecules.
authors.affiliation: Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, People's Republic of China. bhkenlo@cityu.edu.hk
authors.forename: Kenneth Kam-Wing
authors.initials: KK
authors.lastname: Lo
authors.forename: Bruce Ting-Ngok
authors.initials: BT
authors.lastname: Chan
authors.forename: Hua-Wei
authors.initials: HW
authors.lastname: Liu
authors.forename: Kenneth Yin
authors.initials: KY
authors.lastname: Zhang
authors.forename: Steve Po-Yam
authors.initials: SP
authors.lastname: Li
authors.forename: Tommy Siu-Ming
authors.initials: TS
authors.lastname: Tang
mesh_terms: D000818:Animals; D016466:CHO Cells; D056831:Coordination Complexes / Q000737:chemistry*; D006224:Cricetinae; D003412:Cricetulus; D005456:Fluorescent Dyes / Q000737:chemistry*; D007495:Iridium / Q000737:chemistry*; D018613:Microscopy, Confocal; D011725:Pyridines / Q000737:chemistry*
chemical_list: D056831:Coordination Complexes; D005456:Fluorescent Dyes; D011725:Pyridines; D007495:Iridium; C023666:pyridine