title: Cytokinesis: RhoGEFs control a developmental cleavage switch.
abstract: New findings provide evidence that developmentally staged RhoGEFs control assembly of two alternative forms of cleavage furrows: the 'Rappaport' furrows, which govern division of Drosophila syncytial cortical division cycles, and conventional spindle-directed furrows.
authors.affiliation: Florida State University, College of Medicine, Department of Biomedical Sciences, 1115 West Call Street, Tallahassee, FL 32306-4300, USA.
authors.forename: Ling-Rong
authors.initials: LR
authors.lastname: Kao
authors.forename: Timothy
authors.initials: T
authors.lastname: Megraw
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins; D002970:Cleavage Stage, Ovum / Q000378:metabolism*; D004330:Drosophila / Q000196:embryology*; D029721:Drosophila Proteins / Q000378:metabolism*; D004625:Embryo, Nonmammalian / Q000378:metabolism*; D020662:Guanine Nucleotide Exchange Factors / Q000378:metabolism*; D064067:Rho Guanine Nucleotide Exchange Factors; D020741:rho GTP-Binding Proteins / Q000378:metabolism*
chemical_list: D018797:Cell Cycle Proteins; D029721:Drosophila Proteins; D020662:Guanine Nucleotide Exchange Factors; C121865:Pbl protein, Drosophila; D064067:Rho Guanine Nucleotide Exchange Factors; C465504:sav protein, Drosophila; D020741:rho GTP-Binding Proteins