title: Reactive oxygen species generation in fungal development and pathogenesis.
abstract: Reactive oxygen species (ROS) generated by NADPH-dependent oxidases (Nox) have been shown to function as signaling molecules and to be essential for many differentiation processes in mammals and plants. There is growing evidence that ROS are important for many aspects of fungal life including vegetative hyphal growth, differentiation of conidial anastomosis tubes, fruiting body and infection structure formation, and for induction of apoptosis. Recent results from studies in fungal saprophytic and pathogenic model systems have shed new light on the role of Nox in cytoskeleton organization, the structure of Nox complexes and links to components of the apical complex, and the localization of Nox to the endoplasmic reticulum.
authors.affiliation: Institut für Biologie und Biotechnologie der Pflanzen, Westf. Wilhelms Universitaet, Schlossplatz 8, D-48143 Muenster, Germany. tudzyns@uni-muenster.de
authors.forename: Paul
authors.initials: P
authors.lastname: Tudzynski
authors.forename: Jens
authors.initials: J
authors.lastname: Heller
authors.forename: Ulrike
authors.initials: U
authors.lastname: Siegmund
mesh_terms: D017209:Apoptosis; D048690:Fruiting Bodies, Fungal / Q000254:growth & development; D005658:Fungi / Q000254:growth & development / Q000378:metabolism / Q000472:pathogenicity / Q000502:physiology*; D025301:Hyphae / Q000254:growth & development; D019255:NADPH Oxidases / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D013172:Spores, Fungal / Q000254:growth & development
chemical_list: D017382:Reactive Oxygen Species; D019255:NADPH Oxidases