title: Endobronchial instillations of amphotericin B: complementary treatment for pulmonary mucormycosis.
abstract: Pulmonary mucormycosis is a rare fungal infection that appears in patients with hematologic diseases who are immunosuppressed by chemotherapy. We report a case of pulmonary mucormycosis in a 21-year-old man with acute lymphoblastic leukaemia. During the period of pancytopenia he developed invasive mucormycosis. His initial symptoms were pleuritic chest pain with fever and unresponsiveness to broad-spectrum antibiotics. The outcome was favorable after long-term systemic and aerosolized amphotericin B, endobronchial instillations of amphotericin B, posaconazole, and surgery.
authors.affiliation: *Respiratory Unit †Department of Hematology, Valme University Hospital, Seville, Spain.
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Alfageme
authors.forename: Angela
authors.initials: A
authors.lastname: Reina
authors.forename: Javier
authors.initials: J
authors.lastname: Gallego
authors.forename: Nuria
authors.initials: N
authors.lastname: Reyes
authors.forename: Angeles
authors.initials: A
authors.lastname: Torres