title: Foot ulcers caused by rheumatoid vasculitis in a patient with rheumatoid arthritis undergoing etanercept treatment.
abstract: A 59-year-old woman with a 10-year history of rheumatoid arthritis (RA) presented with chronic ulcers on both feet while undergoing treatment with etanercept. Rheumatoid vasculitis (RV) was diagnosed, and the patient was treated with immunosuppressant drugs and skin grafting. Although anti-tumor necrosis factor (TNF) agents are known to induce vasculitis, vasculitis can also be caused by active RA. Accordingly, the cause of vasculitis in RA patients receiving anti-TNF therapy must be evaluated carefully.
authors.affiliation: Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Japan.
authors.forename: Takamasa
authors.initials: T
authors.lastname: Murosaki
authors.forename: Takao
authors.initials: T
authors.lastname: Nagashima
authors.forename: Yoko
authors.initials: Y
authors.lastname: Aoki
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Imai
authors.forename: Masahiro
authors.initials: M
authors.lastname: Iwamoto
authors.forename: Seiji
authors.initials: S
authors.lastname: Minota
mesh_terms: D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy*; D000068800:Etanercept; D005260:Female; D016523:Foot Ulcer / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007074:Immunoglobulin G / Q000009:adverse effects*; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008875:Middle Aged; D018124:Receptors, Tumor Necrosis Factor; D056653:Rheumatoid Vasculitis / Q000209:etiology*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D018124:Receptors, Tumor Necrosis Factor; D014409:Tumor Necrosis Factor-alpha; D000068800:Etanercept