title: Organizing pneumonia complicated by cyst and pneumothorax formation.
abstract: We present a case of organizing pneumonia complicated by pneumothorax in association with cyst formation that developed during corticosteroid treatment. Although it has been reported that the check-valve mechanism is a plausible cause of cyst and pneumothorax formation in patients with organizing pneumonia, the details of the corresponding pathological changes that occur in air-trapping have not been elucidated. A pathological examination of lung specimens obtained with video-assisted thoracoscopic surgery suggested that granulation tissues plugging the bronchiole lumens might be a potential cause of the check-valve mechanism in this case. In this report, we also reviewed eight other cases of organizing pneumonia with pneumothorax or cyst formation.
authors.affiliation: Department of Respiratory Medicine, Jikei University Hospital, Japan. tkskdt@jikei.ac.jp
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Kadota
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Shimizu
authors.forename: Chikako
authors.initials: C
authors.lastname: Tsurushige
authors.forename: Makoto
authors.initials: M
authors.lastname: Kawaishi
authors.forename: Jun
authors.initials: J
authors.lastname: Araya
authors.forename: Katsutoshi
authors.initials: K
authors.lastname: Nakayama
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Kuwano
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hano
mesh_terms: D000305:Adrenal Cortex Hormones / Q000009:adverse effects; D000328:Adult; D003560:Cysts / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D011014:Pneumonia / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011030:Pneumothorax / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D020775:Thoracic Surgery, Video-Assisted; D014057:Tomography, X-Ray Computed
chemical_list: D000305:Adrenal Cortex Hormones