title: Peritoneal access, transgastric peritoneoscopy and oophorectomy - feasibility study on an experimental Swine model.
abstract: OBJECTIVE
  Natural orifice translumenal endoscopic surgery (NOTES) still poses numerous challenges, even in cases of relatively simple surgical procedures. This study aims to assess the feasibility of transgastric resectional interventions using commonly available endoscopic equipment as well as to offer a safe closure method of the gastric access site.
  
  
  METHODS
  Ten pigs underwent pure transgastric endoscopic oophorectomy using a single channel endoscope. The gastric defect was closed using over-the-scope clips (OTSC™, OVESCO Endoscopy). After 2 weeks the animals underwent autopsies.
  
  
  RESULTS
  All procedures were successful. Transgastric access time varied from 4.46 to 33.24 minutes. The peritoneal exploration took 31 minutes and oophorectomy needed in average of 21 minutes (range 15-28 minutes). The animals for which the gastric access site was closed with OTSC™ survived for 2 weeks without complications.
  
  
  CONCLUSIONS
  This study demonstrates the technical feasibility and safety of pure transgastric endoscopic oophorectomy using conventional endoscopic instrumentation in a porcine model. OTSC™ closure system is an easy to use and reliable gastric closure method.
authors.forename: Valeriu
authors.initials: V
authors.lastname: Surlin
authors.forename: Stefan
authors.initials: S
authors.lastname: Patrascu
authors.forename: Sandu
authors.initials: S
authors.lastname: Ramboiu
authors.forename: Simona
authors.initials: S
authors.lastname: Fronie
authors.forename: Adrian
authors.initials: A
authors.lastname: Saftoiu
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D057605:Natural Orifice Endoscopic Surgery / Q000379:methods*; D010052:Ovariectomy; D013270:Stomach / Q000601:surgery; D015996:Survival Rate; D013552:Swine