title: Identity crisis: it's not just Foxp3 anymore.
abstract: What does it take to make a regulatory T (Treg) cell? In this issue of Immunity, Ohkura et al. show that Treg-cell-specific CpG hypomethylation and Foxp3 expression are independent events required for Treg cell development, stability, and full suppressive activity.
authors.affiliation: Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
authors.forename: Greg M
authors.initials: GM
authors.lastname: Delgoffe
authors.forename: Matthew L
authors.initials: ML
authors.lastname: Bettini
authors.forename: Dario A A
authors.initials: DA
authors.lastname: Vignali