title: Case of Reye's syndrome accompanied by hemolytic anemia and cardiac injury after cytomegalovirus infection.
abstract: A 6-month-old girl with active human cytomegalovirus (HCMV) infection developed Reye's syndrome after vaccination. She suffered from uncommon complications of HCMV infection, including Coombs-negative hemolytic anemia and cardiac injury, but recovered after the appropriate treatment with prompt ganciclovir and symptomatic support. However, the patient died later as a result of a viral upper respiratory tract infection, which aggravated the primary disease. This case suggests that HCMV infection might be a causative agent of Reye's syndrome.
authors.affiliation: Virus Laboratory, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China. qiy@sj-hospital.org
authors.forename: Ying
authors.initials: Y
authors.lastname: Qi
authors.forename: Xiaomei
authors.initials: X
authors.lastname: Liu
authors.forename: Wei
authors.initials: W
authors.lastname: Xu
authors.forename: Qiang
authors.initials: Q
authors.lastname: Ruan
mesh_terms: D000743:Anemia, Hemolytic / Q000150:complications* / Q000175:diagnosis*; D000998:Antiviral Agents / Q000008:administration & dosage; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy; D005260:Female; D015774:Ganciclovir / Q000008:administration & dosage; D006331:Heart Diseases / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D012202:Reye Syndrome / Q000150:complications* / Q000175:diagnosis*; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D015774:Ganciclovir