title: Percutaneous implantation of a ventricular partitioning device for treatment of ischemic heart failure: initial experience of a center.
abstract: The Parachute is a novel left ventricular (LV) partitioning device that is deployed percutaneously in the left ventricle in patients with anteroapical regional wall motion abnormalities, dilated LV and systolic dysfunction after anterior myocardial infarction (MI). The implantable device is a partitioning membrane that isolates the dysfunctional region of the ventricle and decreases chamber volume. Data from the first-in-human clinical trial - the Percutaneous Ventricular Restoration in Chronic Heart Failure (PARACHUTE) trial- has shown that this new device is associated with significant and sustained LV volume reduction and improvement in LV hemodynamics and functional capacity in the 12 months after implantation, with a relatively low rate of clinical events, indicating that it may have a beneficial effect in the treatment of ischemic heart failure. We aim to describe our initial experience with implantation of the Parachute LV partitioning device and its short-term safety, defined as the successful delivery and deployment of the device.
authors.affiliation: Serviço de Cardiologia, Centro Hospitalar de Vila Nova de Gaia/Espinho-EPE, Vila Nova de Gaia, Portugal. gmadeira.silva@gmail.com
authors.forename: Guida
authors.initials: G
authors.lastname: Silva
authors.forename: Bruno
authors.initials: B
authors.lastname: Melica
authors.forename: Gustavo
authors.initials: G
authors.lastname: Pires de Morais
authors.forename: Olga
authors.initials: O
authors.lastname: Sousa
authors.forename: Nuno
authors.initials: N
authors.lastname: Bettencourt
authors.forename: José
authors.initials: J
authors.lastname: Ribeiro
authors.forename: Lino
authors.initials: L
authors.lastname: Simões
authors.forename: Vasco
authors.initials: V
authors.lastname: Gama
mesh_terms: D006348:Cardiac Surgical Procedures / Q000379:methods; D006333:Heart Failure / Q000209:etiology / Q000601:surgery*; D006352:Heart Ventricles; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications / Q000601:surgery*; D019736:Prostheses and Implants; D019919:Prosthesis Implantation / Q000379:methods*