title: Job strain and incident metabolic syndrome over 5 years of follow-up: the coronary artery risk development in young adults study.
abstract: BACKGROUND
  Theories of stress-induced metabolic syndrome predict that job strain would increase risk. Few studies have evaluated this association.
  
  
  OBJECTIVE
  To evaluate the association between job strain and the risk of metabolic syndrome.
  
  
  METHODS
  We investigated associations between job strain and incident metabolic syndrome adjusted for sociodemographic factors, health behaviors, and depressive symptoms over 5 years among 2966 black and white men and women in the Coronary Artery Risk Development in Young Adults study. Job strain was categorized by Karasek's model: high demands/low control; high demands/high control; low demands/low control; and low demands/high control.
  
  
  RESULTS
  Compared with persons in low-strain jobs, men in active jobs (adjusted hazards ratio, 2.7; 95% confidence interval, 1.5 to 4.9) and women in high strain jobs (adjusted hazards ratio, 2.2; 95% confidence interval, 1.0 to 4.6) had significantly increased risk of metabolic syndrome.
  
  
  CONCLUSIONS
  Job strain may be a modifiable risk factor for metabolic syndrome and subsequent cardiovascular disease.
authors.affiliation: Department of Mathematics and Statistics, University of Vermont, Burlington, Vt 05405, USA. erika.edwards@uvm.edu
authors.forename: Erika M
authors.initials: EM
authors.lastname: Edwards
authors.forename: Sherri O
authors.initials: SO
authors.lastname: Stuver
authors.forename: Timothy C
authors.initials: TC
authors.lastname: Heeren
authors.forename: Lisa
authors.initials: L
authors.lastname: Fredman
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000523:psychology*; D009784:Occupational Diseases / Q000523:psychology*; D016016:Proportional Hazards Models; D012307:Risk Factors; D013315:Stress, Psychological / Q000150:complications* / Q000175:diagnosis; D011795:Surveys and Questionnaires; D055815:Young Adult