title: Translating the combination of TGFβ blockade and radiotherapy into clinical development in glioblastoma.
abstract: To improve multimodal glioblastoma treatment strategies, it appears useful to integrate a selective inhibitor of the TβR-I kinase, which may be able to potentiate radiation responses by increasing apoptosis and cancer-stem-like cell targeting while blocking DNA damage repair, invasion, mesenchymal transition and angiogenesis.1.
authors.affiliation: Departments of Translational Radiation Oncology, German Cancer Research Center (DKFZ); Heidelberg, Germany ; Department of Radiation Oncology; University Hospital Center; Heidelberg, Germany ; Department of Oncology; Tongji Hospital, Tongji Medical College; Huazhong University of Science and Technology; Wuhan, China.
authors.forename: Mengxian
authors.initials: M
authors.lastname: Zhang
authors.forename: Michael
authors.initials: M
authors.lastname: Lahn
authors.forename: Peter E
authors.initials: PE
authors.lastname: Huber