title: [Infection frequency in patients with chronic idiopathic ulcerative colitis].
abstract: BACKGROUND
  Ulcerative Colitis (UC) is a chronic inflammatory bowel disease characterized by diffuse inflammation of the mucosa of the colon. Up to now, diverse observational studies have implicated a wide variety of pathogenic microorganisms as causal and exacerbating factors in UC. Clostridium difficile (C. difficile) infection has been associated with recurrence and treatment failure and its incidence in patients with UC has been on the rise in the last few years.
  
  
  OBJECTIVE
  To determine the frequency of infection by different microorganisms in Mexican UC patients.
  
  
  METHODS
  A total of 150 patients with definitive UC diagnosis were studied. All the stool tests for parasites and ova, stool cultures, tests for the C. difficile toxins A and B, and immunohistochemistry for Cytomegalovirus in colon segment biopsies were analyzed. Other demographic and clinical variables of the disease were recorded for their correlation with infection frequency.
  
  
  RESULTS
  Infection frequency in UC patients was 28.00%. C. difficile infection was present in 0.013%. Other pathogens were found, such as Endolimax nana (9.00%), Entamoeba histolytica (3.00%), Cytomegalovirus (2.00%), Salmonella (2.00%), Shigella (0.70%), Toxoplasma gondii (0.70%) and Iodamoeba bütschlii (0.70%).
  
  
  CONCLUSIONS
  Infection frequency was 28.00% in our study and C. difficile infection represented only 0.013%.
authors.affiliation: Clínica de Enfermedad Inflamatoria Intestinal, Departamento de Gastroenterología, Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", México D.F., México. kazuofurusho@hotmail.com
authors.forename: J K
authors.initials: JK
authors.lastname: Yamamoto-Furusho
authors.forename: J L
authors.initials: JL
authors.lastname: de León-Rendón
authors.forename: L
authors.initials: L
authors.lastname: Rodas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D016360:Clostridioides difficile; D003093:Colitis, Ulcerative / Q000150:complications* / Q000453:epidemiology* / Q000382:microbiology; D004761:Enterocolitis, Pseudomembranous / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D007239:Infections / Q000453:epidemiology* / Q000209:etiology* / Q000382:microbiology; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D012008:Recurrence; D017211:Treatment Failure; D055815:Young Adult