title: Synthesis and potential use of 1,8-naphthalimide type (1)O2 sensor molecules.
abstract: New double (fluorescent and spin) sensor molecules containing 4-amino substituted 1,8-naphthalimide as a fluorophore and a sterically hindered amine (pre-nitroxide) or pyrroline nitroxide as a quencher and radical capturing moiety were synthesized. All sensors were substituted with a diethylaminoethyl side-chain to increase the water solubility. Steady state fluorescence properties of these compounds and their responses to ROS in vitro are reported with perspectives of plant physiology use in vivo.
authors.affiliation: Department of Organic and Medicinal Chemistry, University of Pécs, Pécs, Hungary.
authors.forename: Tamás
authors.initials: T
authors.lastname: Kálai
authors.forename: Éva
authors.initials: É
authors.lastname: Hideg
authors.forename: Ferhan
authors.initials: F
authors.lastname: Ayaydin
authors.forename: Kálmán
authors.initials: K
authors.lastname: Hideg
mesh_terms: D000588:Amines / Q000737:chemistry; D000812:Anhydrides / Q000138:chemical synthesis* / Q000737:chemistry*; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D060326:Chemistry Techniques, Synthetic; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry*; D007094:Imides / Q000737:chemistry; D009281:Naphthalenes / Q000138:chemical synthesis* / Q000737:chemistry*; D018515:Plant Leaves / Q000378:metabolism / Q000502:physiology; D011758:Pyrroles / Q000737:chemistry; D026082:Singlet Oxygen / Q000378:metabolism*; D014026:Nicotiana / Q000378:metabolism / Q000502:physiology
chemical_list: C578448:4-nitro-1,8-naphthalic anhydride; D000588:Amines; D000812:Anhydrides; D005456:Fluorescent Dyes; D007094:Imides; D009281:Naphthalenes; D011758:Pyrroles; D026082:Singlet Oxygen; C013231:pyrroline