title: Evaluation of the impact of uveitis on visual-related quality of life.
abstract: OBJECTIVE
  To determine quality of life in patients with uveitis and investigate the association between clinical parameters of uveitis and visual functioning.
  
  
  METHODS
  Prospective cross-sectional study. The interviewer- administered National Eye Institute visual function questionnaire (VFQ-25) was used in 117 adult outpatient uveitic patients. Their scores were compared against 48 controls with no ocular history. Subgroup differences amongst the patients were compared using Mann-Whitney and Kruskal-Wallis test. Multiple regression analysis was performed to determine the associations of visual function and disease characteristics of uveitis.
  
  
  RESULTS
  VFQ-25 composite scores for patients were significantly lower than controls in all domains except driving. In multivariable analysis, lower VFQ-25 composite scores were associated with a chronic course of disease, even after taking into account the influences of visual acuity, treatment regimes and location of disease.
  
  
  CONCLUSIONS
  Uveitic patients reported poorer visual functioning. A chronic course of disease is associated with poorer functioning.
authors.affiliation: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore, Republic of Singapore. petrina_tan@ttsh.com.sg
authors.forename: Petrina
authors.initials: P
authors.lastname: Tan
authors.forename: Yan Tong
authors.initials: YT
authors.lastname: Koh
authors.forename: Poh Ying
authors.initials: PY
authors.lastname: Wong
authors.forename: Stephen C
authors.initials: SC
authors.lastname: Teoh
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011594:Psychometrics / Q000379:methods*; D011788:Quality of Life; D011795:Surveys and Questionnaires; D014605:Uveitis / Q000503:physiopathology* / Q000523:psychology; D014792:Visual Acuity / Q000502:physiology*; D055815:Young Adult