title: A comparison of the clinical features and prognosis of pancreatic head cancer with that of other periampullary cancers.
abstract: OBJECTIVE
  Our purpose was to compare the clinical features and prognosis of pancreatic head cancer with that of other periampullary cancers.
  
  
  METHODS
  The medical records of 82 patients (mean age of 61.67±10.52 years) with ductal adenocarcinoma of the head of pancreas and 73 patients (mean age of 60.52±11.72 years) with other periampullary adenocarcinomas, all of whom had received radical surgery, were retrospectively analyzed.
  
  
  RESULTS
  There were no significant differences in age and gender between the groups (both, p>0.05). However, there were significant differences in lymph node metastasis, TNM stage, clear surgical margins, tumor size, and neural invasion between the 2 groups (all p<0.05). Patients with pancreatic head adenocarcinoma had significantly higher red blood cell (RBC) count and hemoglobin (Hb), albumin and pre-albumin levels, and higher platelet and white blood cell (WBC) counts than the patients with other periampullary adenocarcinomas (all p<0.05). No differences in carcinoembryonic antigen (CEA) or CA19-9 were noted between the groups. The 1-year survival rates were not different between the groups (p=0.299).
  
  
  CONCLUSIONS
  Pancreatic head carcinoma has different clinical manifestations and biological features than other periampullary cancers.
authors.forename: Ye Min
authors.initials: YM
authors.lastname: Liang
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Qi Long
authors.initials: QL
authors.lastname: Sun
authors.forename: Yu Feng
authors.initials: YF
authors.lastname: Cheng
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D021441:Carcinoma, Pancreatic Ductal / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness / Q000473:pathology; D009367:Neoplasm Staging; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies
chemical_list: D014408:Biomarkers, Tumor