title: Phenotyping of mouse models with OCT.
abstract: Optical coherence tomography (OCT) is an invaluable technique to perform noninvasive retinal imaging in small animal models such as mice. It provides virtual cross sections that correlate well with histomorphometric data with the advantage that multiple iterative measurements can be acquired in time line analyses to detect dynamic changes and reduce the amount of animals needed per study.
authors.affiliation: Centre for Ophthalmology, University Eye Hospital, University of Tuebingen, Tuebingen, Germany. dominik.fischer@med.uni-tuebingen.de
authors.forename: M Dominik
authors.initials: MD
authors.lastname: Fischer
authors.forename: Ahmad
authors.initials: A
authors.lastname: Zhour
authors.forename: Christoph J
authors.initials: CJ
authors.lastname: Kernstock
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004867:Equipment Design; D007091:Image Processing, Computer-Assisted / Q000379:methods; D051379:Mice; D012160:Retina / Q000473:pathology*; D012164:Retinal Diseases / Q000473:pathology; D012984:Software; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*