title: Rapidly progressive glomerulonephritis due to anti-glomerular basement membrane disease accompanied by IgA nephropathy: a case report.
abstract: Anti-glomerular basement membrane (anti-GBM) disease is characterized by autoantibodies against antigenic site on type IV collagen of the GBM. The coexistence of anti-GBM disease and other immune complex mediated glomerulonephritis is common. Herein, we describe a patient presented with rapidly progressive glomerulonephritis, who was diagnosed as IgA-mediated nephropathy and was found to have abundant serum anti-glomerular basement membrane IgG antibodies. The patient's renal function improved considerably with intensive immunosuppressive therapy.
authors.forename: Bixia
authors.initials: B
authors.lastname: Gao
authors.forename: Mingxi
authors.initials: M
authors.lastname: Li
authors.forename: Wenli
authors.initials: W
authors.lastname: Xia
authors.forename: Yubin
authors.initials: Y
authors.lastname: Wen
authors.forename: Zhen
authors.initials: Z
authors.lastname: Qu
mesh_terms: D000328:Adult; D019867:Anti-Glomerular Basement Membrane Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D001323:Autoantibodies / Q000097:blood; D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D018450:Disease Progression; D005260:Female; D005455:Fluorescent Antibody Technique; D005921:Glomerulonephritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005922:Glomerulonephritis, IGA / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007668:Kidney / Q000187:drug effects / Q000276:immunology* / Q000473:pathology; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D001323:Autoantibodies; D015415:Biomarkers; D007070:Immunoglobulin A; D007166:Immunosuppressive Agents; C051951:antiglomerular basement membrane antibody