title: Backbone and side-chain ¹H, ¹⁵N and ¹³C assignments of mouse peptide ESP4.
abstract: A peptide or a small protein released from an exocrine gland or in urine is utilized as a chemosignal that elicits social or reproductive behavior in mice. Recently, we identified the male-specific peptide, exocrine gland-secreting peptide 1 (ESP1), in mouse tear fluids that enhanced female sexual receptive behavior, and determined the three dimensional structure. ESP1 appears to be a member of multigene family that consists of 38 genes in mice, which we call the ESP family. ESP4, a member of the ESP family, is expressed in various exocrine glands, and shows the highest sequence similarity with ESP1. Here, we report the NMR assignments of ESP4 which provides a basis for NMR analyses of this protein. Our results will give insight into structural relationships within the ESP family.
authors.affiliation: Faculty of Life Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto, 862-0973, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Taniguchi
authors.forename: Sosuke
authors.initials: S
authors.lastname: Yoshinaga
authors.forename: Sachiko
authors.initials: S
authors.lastname: Haga-Yamanaka
authors.forename: Kazushige
authors.initials: K
authors.lastname: Touhara
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Terasawa
mesh_terms: D000818:Animals; D002247:Carbon Isotopes; D005260:Female; D006859:Hydrogen; D008297:Male; D051379:Mice; D009587:Nitrogen Isotopes; D019906:Nuclear Magnetic Resonance, Biomolecular; D010455:Peptides / Q000737:chemistry*; D017433:Protein Structure, Secondary
chemical_list: D002247:Carbon Isotopes; D009587:Nitrogen Isotopes; D010455:Peptides; C000592918:exocrine gland-secreting peptide 4, mouse; D006859:Hydrogen