title: [Diagnosis of IgG4-related systemic disease in a patient with an ocular tumor associated with lung nodules].
abstract: The IgG4-related systemic disease is a recently described entity of fibro-inflammatory systemic damage. Although initially described in some forms of pancreatitis, the disease can affect all organs. The common histological features include a lymphoplasmacytic infiltration (especially to IgG4), fibrosis and phlebitis. Elevated serum level of IgG4 is also often present. This rare but certainly underdiagnosed disease must be kept in mind of all clinician faced to a non-specific inflammatory lesion. We report a case of ocular inflammation and lung tumors in a patient of 84 years for which the diagnosis was made through immunolabelling with IgG4 in lesions biopsied.
authors.affiliation: Centre de soins de suite et de rééducation, La Maison du Mineur, 577, avenue Henri-Giraud, 06141 Vence cedex, France. f.vandenbos@maisondumineur.com
authors.forename: F
authors.initials: F
authors.lastname: Vandenbos
authors.forename: M
authors.initials: M
authors.lastname: Benchetrit
authors.forename: N
authors.initials: N
authors.lastname: Tieulié
authors.forename: D
authors.initials: D
authors.lastname: Ambrosetti
authors.forename: S
authors.initials: S
authors.lastname: Chanalet
authors.forename: F
authors.initials: F
authors.lastname: Burel-Vandenbos
mesh_terms: D000369:Aged, 80 and over; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008171:Lung Diseases / Q000188:drug therapy / Q000276:immunology*; D016727:Orbital Pseudotumor / Q000188:drug therapy / Q000276:immunology*
chemical_list: D005938:Glucocorticoids; D007074:Immunoglobulin G