title: Rapidly progressive thyroid mass:  amyloid goiter.
abstract: Amyloidosis is a disease of unknown etiology characterized by the accumulation of an amorphous proteinaceous material in various organs and tissues of the body. Amyloid goiter is an exceedingly rare pathologic condition due to massive amyloid infiltration of the thyroid tissue. Amyloid goiter occurs in association with both primary and secondary systemic amyloidosis, more commonly in the latter. Preoperatively, it simulates a multinodular goiter, and surgical intervention is often necessary to establish a diagnosis and to relieve compressive symptoms of a neck mass. We present the case of an 85-year-old female patient who presented with a rapidly enlarging goiter. Histologic examination confirmed amyloid goiter.
authors.affiliation: Otolaryngology Head and Neck Surgery Department of Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.
authors.forename: Metin
authors.initials: M
authors.lastname: Ibrahimov
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yilmaz
authors.forename: Erkan
authors.initials: E
authors.lastname: Kilic
authors.forename: Ferit
authors.initials: F
authors.lastname: Akil
authors.forename: Resul
authors.initials: R
authors.lastname: Rasidov
authors.forename: Emin
authors.initials: E
authors.lastname: Karaman
mesh_terms: D000369:Aged, 80 and over; D000686:Amyloidosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D003937:Diagnosis, Differential; D004724:Endoscopy; D005260:Female; D006042:Goiter / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D013965:Thyroidectomy; D014057:Tomography, X-Ray Computed