title: In vitro caries-preventive effect of fluoridated orthodontic resins against cariogenic challenge stimulation.
abstract: OBJECTIVE
  The aim of the present study was to evaluate the in vitro caries preventive effect of fluoridated orthodontic resins under pH cycling with two types of acid demineralizing saliva.
  
  
  METHODS
  Brackets were bonded to 120 extracted human premolars, using Rely-a-bond (n = 40), Tru- Bond (n = 40) and Ortho-one (n = 40) orthodontic bonding agents. Each group of resin was divided into 2 subgroups (n = 20): immersion in remineralizing artificial saliva for 14 days and acid saliva with pH 4.3. After 14 days of pH cycling the caries preventive effect on the development of white spot lesion was evaluated considering the presence of inhibition zones to white spot lesions using two scores: 0 = absence and 1 = presence. Kruskal-Wallis ANOVA and Mann-Whitney U tests were used.
  
  
  RESULTS
  Formation of white spot lesions was observed only under pH cycling using acid saliva with pH 4.3; with Rely-a-bond and Tru-Bond being significantly more effective in preventing the appearance of white spot lesions effect than Ortho-one.
  
  
  CONCLUSIONS
  The acidity of the demineralizing solution influenced the formation of white spot lesions around orthodontic brackets under highly cariogenic conditions. Rely-a-bond and Tru-bond presented higher caries-preventive effect than Orthoone.
  
  
  CONCLUSIONS
  The development of fluoride-containing materials cannot be regarded as a permanent means to control dental caries lesions, but a complement along with other preventive methods.
authors.affiliation: Department of Orthodontics, ACPM Dental College, Dhule, Maharashtra India.
authors.forename: Neeraj
authors.initials: N
authors.lastname: Patil
authors.forename: Bhushan
authors.initials: B
authors.lastname: Jawale
authors.forename: Rahul
authors.initials: R
authors.lastname: Redasani
authors.forename: Lalit
authors.initials: L
authors.lastname: Chaudhari
authors.forename: J B
authors.initials: JB
authors.lastname: Garde
authors.forename: Vivek Singh
authors.initials: VS
authors.lastname: Chauhan
mesh_terms: D000704:Analysis of Variance; D017438:Bisphenol A-Glycidyl Methacrylate / Q000627:therapeutic use; D001840:Dental Bonding; D003731:Dental Caries / Q000209:etiology / Q000517:prevention & control*; D004853:Epoxy Resins / Q000627:therapeutic use; D005459:Fluorides / Q000627:therapeutic use*; D006801:Humans; D016910:Orthodontic Brackets / Q000009:adverse effects; D011092:Polyethylene Glycols / Q000627:therapeutic use; D019279:Resin Cements / Q000737:chemistry* / Q000627:therapeutic use*; D012464:Saliva, Artificial / Q000009:adverse effects / Q000737:chemistry; D018709:Statistics, Nonparametric
chemical_list: D004853:Epoxy Resins; C509516:ORTHO-ONE; C097531:Rely a Bond system; D019279:Resin Cements; D012464:Saliva, Artificial; C581063:Tru Bond; D011092:Polyethylene Glycols; D017438:Bisphenol A-Glycidyl Methacrylate; D005459:Fluorides