title: Adult-onset Still's disease revealed by perimyocarditis and a concomitant reactivation of an EBV infection.
abstract: We describe a 17-year-old patient presenting perimyocarditis as the initial manifestation of the adult-onset Still's disease. Corticotherapy was rapidly successful but induced major acute hepatitis in relation with Epstein-Barr virus reactivation. After 1 year, even if the global outcome is favourable, a slightly lowered ejection fraction still persists. Former case reports and differential diagnosis with reactive haemophagocytic syndrome would be discussed.
authors.affiliation: Department of Internal Medicine and Infectious Diseases, Versailles Hospital, Le Chesnay, France. rmeckenstock@ch-versailles.fr
authors.forename: Roderich
authors.initials: R
authors.lastname: Meckenstock
authors.forename: Audrey
authors.initials: A
authors.lastname: Therby
authors.forename: Geraldine
authors.initials: G
authors.lastname: Gibault-Genty
authors.forename: David
authors.initials: D
authors.lastname: Khau
authors.forename: Sebastien
authors.initials: S
authors.lastname: Monnier
authors.forename: Alix
authors.initials: A
authors.lastname: Greder-Belan
mesh_terms: D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000009:adverse effects / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis; D003937:Diagnosis, Differential; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004452:Echocardiography; D020031:Epstein-Barr Virus Infections / Q000175:diagnosis*; D006352:Heart Ventricles / Q000473:pathology; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D009205:Myocarditis / Q000175:diagnosis*; D009206:Myocardium / Q000473:pathology; D010493:Pericarditis / Q000175:diagnosis*; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use; D016706:Still's Disease, Adult-Onset / Q000175:diagnosis* / Q000188:drug therapy; D014775:Virus Activation
chemical_list: D000893:Anti-Inflammatory Agents; D011241:Prednisone