title: Biosynthetic studies on water-soluble derivative 5c (DTX5c).
abstract: The dinoflagellate Prorocentrum belizeanum is responsible for the production of several toxins involved in the red tide phenomenon known as Diarrhetic Shellfish Poisoning (DSP). In this paper we report on the biosynthetic origin of an okadaic acid water-soluble ester derivative, DTX5c, on the basis of the spectroscopical analysis of ¹³C enriched samples obtained by addition of labelled sodium [l-¹³C], [2-¹³C] acetate to artificial cultures of this dinoflagellate.
authors.affiliation: University Institute for Bio-Organic Chemistry "Antonio González", University of La Laguna, Av. Astrofísico Francisco Sánchez 2, La Laguna 38206, Spain.
authors.forename: Tamara S
authors.initials: TS
authors.lastname: Vilches
authors.affiliation: University Institute for Bio-Organic Chemistry "Antonio González", University of La Laguna, Av. Astrofísico Francisco Sánchez 2, La Laguna 38206, Spain.|Department of Organic Chemistry, Faculty of Pharmacy, University of La Laguna, Av. Astrofísico Francisco Sánchez s/n, La Laguna 38206, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Norte
authors.affiliation: University Institute for Bio-Organic Chemistry "Antonio González", University of La Laguna, Av. Astrofísico Francisco Sánchez 2, La Laguna 38206, Spain.|Department of Chemical Engineering and Pharmaceutical Technology, Faculty of Pharmacy, University of La Laguna, Av. Astrofísico Francisco Sánchez s/n, La Laguna 38206, Spain.
authors.forename: Antonio Hernández
authors.initials: AH
authors.lastname: Daranas
authors.affiliation: University Institute for Bio-Organic Chemistry "Antonio González", University of La Laguna, Av. Astrofísico Francisco Sánchez 2, La Laguna 38206, Spain.|Department of Organic Chemistry, Faculty of Pharmacy, University of La Laguna, Av. Astrofísico Francisco Sánchez s/n, La Laguna 38206, Spain.
authors.forename: José J
authors.initials: JJ
authors.lastname: Fernández
mesh_terms: D004141:Dinoflagellida / Q000378:metabolism*; D015394:Molecular Structure; D019319:Okadaic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism
chemical_list: C513094:DTX5c compound; D019319:Okadaic Acid