title: Specificity may be overrated in cancer immunotherapy: Getting to know the nonspecific side of memory T Cells.
abstract: For a long time, cancer immunotherapy has focused on the induction of tumor-specific T cell-mediated immune responses. Now, a mounting body of evidence indicates that efficient anticancer immune responses also rely on innate immunity. Tietze et al. have recently elucidated an antigen-nonspecific role for memory CD8(+) T cells in cytokine-based cancer immunotherapy.
authors.affiliation: Department of Dermatology; University of California; Davis School of Medicine; Sacramento, CA USA.
authors.forename: Gail D
authors.initials: GD
authors.lastname: Sckisel
authors.forename: William J
authors.initials: WJ
authors.lastname: Murphy