title: The impact of race on metabolic disease risk factors in women with and without posttraumatic stress disorder.
abstract: The literature on PTSD and metabolic disease risk factors has been limited by lacking investigation of the potential influence of commonly comorbid disorders and the role of race. In this study data were provided by a sample of 134 women (63 PTSD and 71 without PTSD). Separate sets of models examining associations of psychiatric disorder classifications with metabolic disease risk factors were used. Each model included race (African American or Caucasian), psychiatric disorder, and their interaction. There was an interaction of race and PTSD on body mass index, abdominal obesity, and triglycerides. While PTSD was not generally associated with deleterious health effects in African American participants, PTSD was related to worse metabolic disease risk factors in Caucasians. MDD was associated with metabolic disease risk factors, but there were no interactions with race. Results support the importance of race in the relationship between PTSD and metabolic disease risk factors. Future research would benefit from analysis of cultural factors to explain how race might influence metabolic disease risk factors in PTSD.
authors.affiliation: Durham Veterans Affairs Medical Center, 508 Fulton St. (116 B), Durham, NC 27705, USA. eric.dedert@duke.edu
authors.forename: Eric A
authors.initials: EA
authors.lastname: Dedert
authors.forename: Leia A
authors.initials: LA
authors.lastname: Harper
authors.forename: Patrick S
authors.initials: PS
authors.lastname: Calhoun
authors.forename: Michelle F
authors.initials: MF
authors.lastname: Dennis
authors.forename: Jean C
authors.initials: JC
authors.lastname: Beckham
mesh_terms: D000328:Adult; D001741:Black or African American / Q000523:psychology*; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015897:Comorbidity; D003865:Major Depressive Disorder / Q000097:blood / Q000208:ethnology* / Q000523:psychology*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000208:ethnology* / Q000523:psychology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D056128:Obesity, Abdominal / Q000208:ethnology / Q000523:psychology; D012307:Risk Factors; D013223:Statistics as Topic; D013313:Stress Disorders, Post-Traumatic / Q000097:blood / Q000208:ethnology* / Q000523:psychology*; D019966:Substance-Related Disorders / Q000097:blood / Q000208:ethnology / Q000523:psychology; D014280:Triglycerides / Q000097:blood; D049629:Waist-Hip Ratio; D044465:White People / Q000523:psychology*
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides