title: Dietary fibers and crude protein content alleviate hepatic fat deposition and obesity in broiler breeder hens.
abstract: The effects of inclusion of cellulose or inulin as a source of dietary fiber and CP content of the diet on hepatic fat deposition were investigated in hens fed restricted or close to ad libitum consumption. There were 12 dietary treatments forming a 2 × 3 × 2 factorial with 2 feeding regimens [restricted and liberal (close to ad libitum consumption; LIB)], 3 fiber sources (control, 3% inulin, and 3% cellulose), and 2 levels of CP (14.5 and 17.4%). Hens were assigned in groups of 6 to 60 floor pens. From 43 to 55 wk of age, hens fed LIB showed increased activity of the hepatic malic enzyme (MalE; P < 0.01), which led to an increase (P < 0.001) in liver weight and hepatic lipid deposition and was associated with enhancements (P < 0.05) in plasma levels of glucose, triglyceride, total cholesterol, and low-density lipoprotein cholesterol. Abdominal fat deposition and BW of the hens increased (P < 0.001) with liberal feeding. Inclusion of inulin in the diet reduced (P < 0.05) liver and abdominal fat weight, whereas cellulose inclusion decreased (P < 0.05) feed intake, abdominal fat, and BW. An increase in CP content of the diet from 14.5 to 17.4% reduced MalE activity (P < 0.001), liver weight (P < 0.001), and the accumulation of lipids and cholesterol in the liver, as well as plasma triglyceride concentration and abdominal fat pad weight (P < 0.05). It is concluded that fiber inclusion reduced abdominal fat and liver weight, with effects being more pronounced with cellulose than with inulin. An increase in dietary CP reduced MalE activity and alleviated hepatic and plasma lipid concentration; therefore, it might be a practical approach to reduce the incidence of obesity-linked problems in broiler breeder hens. The combination of high-CP diets and the inclusion of a fiber source did not suppress liver lipid content over that observed with the high-CP diet, exclusively.
authors.affiliation: Department of Animal Science, University College of Agriculture and Natural Resources, University of Tehran, 31587-11167 Karaj, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Mohiti-Asli
authors.forename: M
authors.initials: M
authors.lastname: Shivazad
authors.forename: M
authors.initials: M
authors.lastname: Zaghari
authors.forename: S
authors.initials: S
authors.lastname: Aminzadeh
authors.forename: M
authors.initials: M
authors.lastname: Rezaian
authors.forename: G G
authors.initials: GG
authors.lastname: Mateos
mesh_terms: D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002645:Chickens; D004032:Diet / Q000662:veterinary; D004043:Dietary Fiber; D004044:Dietary Proteins; D005260:Female; D050356:Lipid Metabolism; D008055:Lipids / Q000737:chemistry; D008099:Liver / Q000378:metabolism*; D009765:Obesity / Q000517:prevention & control / Q000662:veterinary*; D011201:Poultry Diseases / Q000517:prevention & control*
chemical_list: D004043:Dietary Fiber; D004044:Dietary Proteins; D008055:Lipids