title: The tandem intermolecular hydroalkoxylation/Claisen rearrangement.
abstract: The Au(I)-catalyzed intermolecular hydroalkoxylation of alkynes with allylic alcohols to provide allyl vinyl ethers that subsequently undergo Claisen rearrangement is reported. This new cascade reaction strategy facilitates the direct formation of γ,δ-unsaturated ketones from simple starting materials in a single step.
authors.affiliation: Department of Chemistry, University of Florida, P. O. Box 117200, Gainesville, FL 32611, USA.
authors.forename: John M
authors.initials: JM
authors.lastname: Ketcham
authors.forename: Berenger
authors.initials: B
authors.lastname: Biannic
authors.forename: Aaron
authors.initials: A
authors.lastname: Aponick
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D004987:Ethers / Q000737:chemistry*; D006046:Gold / Q000737:chemistry; D007659:Ketones / Q000737:chemistry; D020005:Propanols / Q000737:chemistry*
chemical_list: D000480:Alkynes; D004987:Ethers; D007659:Ketones; D020005:Propanols; C006463:allyl alcohol; D006046:Gold