title: Long-term treatment with high-dose of sildenafil in a thalassemic patient with pulmonary hypertension.
abstract: We report a case of a 37-years-old man, affected by thalassemia major, hypogonadotropic hypogonadism, chronic HCV-hepatitis, diabetes mellitus, severe osteoporosis, prior septic pulmonary embolism and pulmonary artery hypertension was performed a long-term treatment with high-dose of sildenafil (120 mg/die) with reduction of pulmonary arterial systolic pressure and of the dyspnea.
authors.affiliation: University of Foggia, Department of Cardiology, Italy. opsfco@tin.it
authors.forename: Michele
authors.initials: M
authors.lastname: Correale
authors.forename: Fiorella
authors.initials: F
authors.lastname: De Rosa
authors.forename: Riccardo
authors.initials: R
authors.lastname: Ieva
authors.forename: Matteo
authors.initials: M
authors.lastname: Di Biase
authors.forename: Natale Daniele
authors.initials: ND
authors.lastname: Brunetti
mesh_terms: D000328:Adult; D015897:Comorbidity; D006525:Hepatitis, Viral, Human / Q000453:epidemiology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000453:epidemiology* / Q000503:physiopathology; D008297:Male; D010879:Piperazines / Q000008:administration & dosage*; D011687:Purines / Q000008:administration & dosage; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000008:administration & dosage*; D014665:Vasodilator Agents / Q000008:administration & dosage*; D017086:beta-Thalassemia / Q000453:epidemiology* / Q000503:physiopathology
chemical_list: D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate