title: The effect of pre-procedure anxiety on sedative requirements for sedation during colonoscopy.
abstract: This study investigated the effects of pre-procedural anxiety (assessed using the Beck Anxiety Inventory) on sedative requirements in 135 patients undergoing sedation for colonoscopy. Deep sedation was defined as loss of consciousness and no response to colonoscopy, and was achieved by target-controlled infusion of propofol. Patients' characteristics, baseline haemodynamic profiles, Beck Anxiety Inventory scores, effect-site propofol concentration at loss of consciousness and characteristics of recovery were recorded. No correlations were found between Beck Anxiety Inventory scores and effect-site propofol concentration at loss of consciousness or baseline haemodynamic profiles. There was no statistical difference in the characteristics of recovery among patients with different levels of anxiety. In conclusion, in patients receiving deep sedation for colonoscopies, the level of pre-procedural anxiety did not relate to the sedative requirement or post-procedural recovery characteristics.
authors.affiliation: Department of Anesthesiology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan. ed102605@gmail.com
authors.forename: K-C
authors.initials: KC
authors.lastname: Chung
authors.forename: S-E
authors.initials: SE
authors.lastname: Juang
authors.forename: K-C
authors.initials: KC
authors.lastname: Lee
authors.forename: W-H
authors.initials: WH
authors.lastname: Hu
authors.forename: C-C
authors.initials: CC
authors.lastname: Lu
authors.forename: H-F
authors.initials: HF
authors.lastname: Lu
authors.forename: K-C
authors.initials: KC
authors.lastname: Hung
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000175:diagnosis / Q000523:psychology*; D003113:Colonoscopy / Q000523:psychology*; D054810:Deep Sedation / Q000379:methods / Q000523:psychology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction / Q000706:statistics & numerical data; D011300:Preoperative Care / Q000379:methods*; D015742:Propofol; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data
chemical_list: D006993:Hypnotics and Sedatives; D015742:Propofol