title: [Comparison of clinical manifestations between Mycobacterium avium-intracellulare complex and Mycobacterium abscessus pulmonary diseases].
abstract: OBJECTIVE
  To compare the clinical manifestations of nontuberculous mycobacterial (NTM) pulmonary diseases caused by Mycobacterium avium-intracellulare complex (MAC) and Mycobacterium abscessus.
  
  
  METHODS
  The clinical manifestations of 18 patients with MAC and 9 patients with Mycobacterium abscessus pulmonary diseases diagnosed from 2010 to 2011 were reviewed.
  
  
  RESULTS
  There were no significant differences in the gender, age, body mass index, predisposed diseases, symptoms and positive sputum acid-fast bacillus between MAC and Mycobacterium abscessus groups. Upper lobe cavities were more frequently observed in the MAC group (13/18), whereas nodular bronchiectatic changes were more frequent in the Mycobacterium abscessus group (3/9). Compared with MAC pulmonary diseases, several imaging characteristics were more common in the Mycobacterium abscessus group, including bilateral micro nodules (Mycobacterium abscessus group 8/9 vs MAC group 7/18), tree-in-bud sign (Mycobacterium abscessus group 7/9 vs MAC group 6/18) and multiple bronchiectasis (Mycobacterium abscessus group 8/9 vs MAC group 5/18).
  
  
  CONCLUSIONS
  There was considerable overlap in clinical characteristics of MAC and Mycobacterium abscessus pulmonary diseases. However, bilateral micro nodules, tree-in-bud sign and multiple bronchiectasis were more frequently seen in Mycobacterium abscessus than in MAC pulmonary diseases, while upper lobe cavities were more frequently seen in MAC than in Mycobacterium abscessus pulmonary diseases.
authors.affiliation: Department of Tuberculosis, Beijng Tuberculosis & Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.
authors.forename: Hong-fei
authors.initials: HF
authors.lastname: Duan
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.forename: Nai-hui
authors.initials: NH
authors.lastname: Chu
authors.forename: Xue-rui
authors.initials: XR
authors.lastname: Huang
authors.forename: Qing-feng
authors.initials: QF
authors.lastname: Wang
authors.forename: Hai-rong
authors.initials: HR
authors.lastname: Huang
authors.forename: Qian
authors.initials: Q
authors.lastname: Liang
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008169:Lung Abscess / Q000175:diagnosis* / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D015269:Mycobacterium avium Complex; D015270:Mycobacterium avium-intracellulare Infection / Q000175:diagnosis*; D009170:Nontuberculous Mycobacteria; D012189:Retrospective Studies