title: Primary giant lymphoma of the right thigh: A case report and brief review of the literature.
abstract: Primary soft tissue non-Hodgkin lymphoma (NHL) of the extremities is very rare. The clinical features of NHL mimic those of other soft tissue tumors, particularly sarcoma; however, they should be differentiated, as the treatment and prognosis are completely different. In this study, the case of a 68-year-old female with a giant mass, movement disorder, numbness and painful sensations in the right thigh is presented. Magnetic resonance (MR) imaging revealed a huge circle-shaped mass. Fine needle aspiration cytology (FNAC) of the tumor demonstrated neoplastic small, round cells. The tentative diagnosis was of a mesenchymal sarcoma. The right thigh was amputated. On histological examination of the amputated extremity, the diagnosis was found to be large B cell lymphoma. Primary soft tissue NHL of the extremities is a systemic malignant disease and is sensitive to chemo-therapy and radiotherapy. The histological diagnosis should be identified as far as possible before the tumor is widely excised.
authors.affiliation: Departments of Hematology.
authors.forename: Yu-Huan
authors.initials: YH
authors.lastname: Gao
authors.forename: Qian
authors.initials: Q
authors.lastname: Xu
authors.forename: Guangchuan
authors.initials: G
authors.lastname: Wei
authors.forename: Hai-Sheng
authors.initials: HS
authors.lastname: Liu
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Wu
authors.forename: Li-Hong
authors.initials: LH
authors.lastname: Liu
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Wu
authors.forename: Gui-Min
authors.initials: GM
authors.lastname: Zhao
authors.forename: Lan-Ping
authors.initials: LP
authors.lastname: Diao