title: Combined hamartoma of the retina and retinal pigment epithelium.
abstract: We report two cases of combined hamatoma of the retina and retinal pigment epithelium (CHR-RPE), illustrated with ultrasonography, optical coherence tomography, fundus fluorescein angiography and indocyanine green angiography images. CHR-RPE could clinically mimic several other retinal conditions. Failure to distinguish it from serious malignancies such as choroidal melanoma or retinoblastoma has led to unnecessary enucleation in the past. Through these case reports and a review of literature, we show the diagnostic features of CHR-RPE, its key differential diagnoses and the management options.
authors.affiliation: Prince Charles Eye Unit, King Edward VII Hospital, Windsor, UK. kanminxue@gmail.com
authors.forename: Kanmin
authors.initials: K
authors.lastname: Xue
authors.forename: Faye
authors.initials: F
authors.lastname: Mellington
authors.forename: Irina
authors.initials: I
authors.lastname: Gout
authors.forename: Sofia
authors.initials: S
authors.lastname: Rokerya
authors.forename: Oyinkan Ibironke
authors.initials: OI
authors.lastname: Olurin
authors.forename: Ahmed
authors.initials: A
authors.lastname: El-Amir
mesh_terms: D000293:Adolescent; D000328:Adult; D000792:Angiography; D004396:Coloring Agents; D003937:Diagnosis, Differential; D019793:Fluorescein; D005456:Fluorescent Dyes; D006222:Hamartoma / Q000000981:diagnostic imaging*; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D019572:Retinal Neoplasms / Q000000981:diagnostic imaging*; D055213:Retinal Pigment Epithelium / Q000000981:diagnostic imaging*; D041623:Tomography, Optical Coherence; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D004396:Coloring Agents; D005456:Fluorescent Dyes; D007208:Indocyanine Green; D019793:Fluorescein