title: Nanotechnologies and regenerative medical approaches for space and terrestrial medicine.
abstract: One purpose of the International Space Station (ISS) is to explore powerful new areas of biomedical science in microgravity. Recent advances in nanotechnology applied to medicine--what we now refer to as nano-medicine--and regenerative medicine have enormous untapped potential for future space and terrestrial medical applications. Novel means for drug delivery and nanoscale screening tools will one day benefit astronauts venturing to Mars and places beyond, while the space laboratory will foster advances in nanotechnologies for diagnostic and therapeutic tools to help our patients here on Earth. Herein we review a series of nanotechnologies and selected regenerative medical approaches and highlight key areas of ongoing and future investigation that will benefit both space and terrestrial medicine. These studies target significant areas of human disease such as osteoporosis, diabetes, radiation injury, and many others.
authors.affiliation: Department of Nanomedicine, The Methodist Hospital Research Institute, 6670 Bertner Ave., Houston, TX 77030, USA.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Grattoni
authors.forename: Ennio
authors.initials: E
authors.lastname: Tasciotti
authors.forename: Daniel
authors.initials: D
authors.lastname: Fine
authors.forename: Joseph S
authors.initials: JS
authors.lastname: Fernandez-Moure
authors.forename: Jason
authors.initials: J
authors.lastname: Sakamoto
authors.forename: Ye
authors.initials: Y
authors.lastname: Hu
authors.forename: Bradley
authors.initials: B
authors.lastname: Weiner
authors.forename: Mauro
authors.initials: M
authors.lastname: Ferrari
authors.forename: Scott
authors.initials: S
authors.lastname: Parazynski
mesh_terms: D000337:Aerospace Medicine; D016503:Drug Delivery Systems; D006321:Heart; D006801:Humans; D013058:Mass Spectrometry; D008567:Membranes, Artificial; D049329:Nanostructures; D036103:Nanotechnology; D011506:Proteins / Q000737:chemistry; D040901:Proteomics; D044968:Regenerative Medicine; D054457:Tissue Scaffolds
chemical_list: D008567:Membranes, Artificial; D011506:Proteins