title: Validation of a German version of the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E).
abstract: BACKGROUND
  Goal of the present study was the validation of a German version of the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E).
  
  
  METHODS
  197 adult epilepsy patients completed the NDDI-E (185 completed both the NDDI-E and BDI). 95 patients received psychiatric consults.
  
  
  RESULTS
  33 patients received a diagnosis of major depression according to ICD-10 criteria. Internal consistency of the NDDI-E was .83. Receiver operating characteristics (ROC) showed an area under the curve of 0.92. Applying a cutoff score of ≥14 resulted in both sensitivity and specificity of 0.85. In the subsample with psychiatric consult, at the same optimal cutoff, sensitivity was 0.92, and specificity was 0.86. Further analyses showed a high concurrent validity with the BDI.
  
  
  CONCLUSIONS
  The German version of the NDDI-E constitutes a brief and reliable depression screening instrument for epilepsy patients.
authors.affiliation: Freiburg University Medical Center, Epilepsy Center, Germany. birgitta.metternich@uniklinik-freiburg.de
authors.forename: Birgitta
authors.initials: B
authors.lastname: Metternich
authors.forename: Kathrin
authors.initials: K
authors.lastname: Wagner
authors.forename: Franziska
authors.initials: F
authors.lastname: Buschmann
authors.forename: Robin
authors.initials: R
authors.lastname: Anger
authors.forename: Andreas
authors.initials: A
authors.lastname: Schulze-Bonhage
mesh_terms: D000328:Adult; D003865:Major Depressive Disorder / Q000175:diagnosis* / Q000209:etiology; D004827:Epilepsy / Q000150:complications / Q000523:psychology*; D005260:Female; D005858:Germany; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales / Q000592:standards*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014175:Translating