title: Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael-aldol reaction.
abstract: An efficient organocatalyzed strategy for the synthesis of 3-amino-1-indanols has been developed. This method is complementary to the conventional Friedel-Crafts strategy. It is also applicable to the synthesis of enantioenriched 3-amino-1-indanols.
authors.affiliation: Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong SAR, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Qian
authors.forename: Wanxiang
authors.initials: W
authors.lastname: Zhao
authors.forename: Herman H-Y
authors.initials: HH
authors.lastname: Sung
authors.forename: Ian D
authors.initials: ID
authors.lastname: Williams
authors.forename: Jianwei
authors.initials: J
authors.lastname: Sun
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D001372:Aza Compounds / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D007189:Indans / Q000138:chemical synthesis / Q000737:chemistry*; D008968:Molecular Conformation; D012997:Solvents / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000447:Aldehydes; D001372:Aza Compounds; D007189:Indans; D012997:Solvents; C116609:3-hydroxybutanal; C093582:indan