title: Radiotherapy for malignant tumors of the skull base.
abstract: Malignant tumors of the skull base are a fascinating group of tumors arising via disparate causes leading often to similar presentations. This article explores radiotherapy techniques applied to this group of malignancies, with a focus on providing general overview and guiding readers to primary sources to achieve greater depth. The outcomes and effects of radiation, therapeutic radiation modalities and delivery system are discussed. Equipped with these basic principles, practitioners will have general guidance for rational treatment modality selection for patients with skull base tumors.
authors.affiliation: Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA 94143-0226, USA.
authors.forename: Julian
authors.initials: J
authors.lastname: Johnson
authors.forename: Igor J
authors.initials: IJ
authors.lastname: Barani
mesh_terms: D002477:Cells / Q000528:radiation effects; D003131:Combined Modality Therapy; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008579:Meningioma / Q000532:radiotherapy; D009364:Neoplasm Recurrence, Local; D018579:Patient Selection; D011522:Protons; D011830:Radiation Effects; D011878:Radiotherapy / Q000295:instrumentation / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted; D019292:Skull Base Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D013534:Survival
chemical_list: D011522:Protons