title: Can mean platelet volume be a new risk factor in portal venous thrombosis?
abstract: BACKGROUND
  The aim of this study was to discuss the possibility of mean platelet volume (MPV) being a new risk factor in the etiology of portal venous thrombosis (PVT).
  
  
  METHODS
  Study participants were categorized into 2 different groups: group I, control group (n = 35) and group II, PVT group (n = 34). Demographic data and MPV values were recorded retrospectively.
  
  
  RESULTS
  No differences were determined between the 2 groups regarding hypertension, diabetes mellitus, and smoking (P > .05). The average hemoglobin levels were 10.8 ± 2.1 in group II and 14.0 ± 1.7 in group I (P < .001). Although the MPV levels of group II patients were 8.2 ± 0.52, the average level in group I was determined as 7.8 ± 0.62 (P = .012). In the performed receiver-operating characteristic (ROC) analysis, the cutoff value for patients with PVT for MPV was determined as 7.9 (area under curve: 0.674), sensitivity as 70.6%, and specificity as 65.7% (P = .013).
  
  
  CONCLUSIONS
  The current study shows that MPV is significantly higher in patients with PVT than in the control group.
authors.affiliation: Department of General Surgery, Dicle University, Diyarbakır, Turkey. ialiosman@gmail.com
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Aliosmanoglu
authors.forename: Mesut
authors.initials: M
authors.lastname: Gul
authors.forename: Abdullah
authors.initials: A
authors.lastname: Oguz
authors.forename: Omer
authors.initials: O
authors.lastname: Basol
authors.forename: Omer
authors.initials: O
authors.lastname: Uslukaya
authors.forename: Celalettin
authors.initials: C
authors.lastname: Keles
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume / Q000379:methods; D008875:Middle Aged; D012372:ROC Curve; D012307:Risk Factors; D020246:Venous Thrombosis / Q000097:blood* / Q000473:pathology