title: Myxofibrosarcoma of the sinus piriformis: case report and literature review.
abstract: Myxofibrosarcoma is a common sarcoma in the extremities of older people, but is rare in the head and neck region. Here, we report the case of a 42-year-old male patient in whom myxofibrosarcoma generated from the sinus piriformis. Histopathologically, the tumor was characterized by spindle cellular proliferation with moderate cellular density in fibromyxoid stroma. Immunohistochemically, the tumor cells showed positive reactivity for vimentin, Ki-67, smooth muscle actin, and CD34, but negative staining for S-100. Based on these results, the tumor was diagnosed as a low-grade myxofibrosarcoma. Resection of the tumor was performed via a transcervical approach. The patient's postoperative clinical course was uneventful and no local recurrence or distant metastasis has been found so far. The pathology, clinical characteristics, and treatment of myxofibrosarcoma are also reviewed.
authors.affiliation: Department of ear, nose and throat, Changzheng Hospital, No 415, Fengyang Road, Shanghai, Huangpu District, 200003, China.
authors.forename: Zhu
authors.initials: Z
authors.lastname: Qiubei
authors.forename: Lin
authors.initials: L
authors.lastname: Cheng
authors.forename: Xu
authors.initials: X
authors.lastname: Yaping
authors.forename: Lin
authors.initials: L
authors.lastname: Shunzhang
authors.forename: Fan
authors.initials: F
authors.lastname: Jingping
mesh_terms: D000328:Adult; D005354:Fibrosarcoma / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D009236:Myxosarcoma / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D010610:Pharyngeal Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D011379:Prognosis; D012196:Review Literature as Topic