title: A novel strategy for modulation of MDSC to enhance cancer immunotherapy.
abstract: Myeloid derived suppressor cells (MDSC) suppress anti-tumor immune responses. Our recent publication provides evidence that SHIP-1 plays a prominent role in pancreatic tumor development by regulating MDSC. Therefore, SHIP-1 may be a potential therapeutic target for the treatment of MDSC-related hematological malignancies and solid tumors.
authors.affiliation: University of South Florida; Department of Molecular Medicine; Tampa, FL USA.
authors.forename: Tomar
authors.initials: T
authors.lastname: Ghansah