title: Composition and antipseudomonal effect of essential oils isolated from different lavender species.
abstract: The aims of our research include the phytochemical characterization of the essential oils extracted from different lavender species (Lavandula vera L., L. intermedia L., L. pyrenaica DC., and L. stoechas subsp. stoechas) that are important from therapeutic and economic aspects, as well as the optimization of the tube dilution method for microbiological investigation of the effect of essential oils on the selected Pseudomonas strain. The chemical and percentage compositions of the essential oils were analysed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The main component of the essential oils in the majority of lavender species was linalool, while L-fencone was identified in the largest amount in L. stoechas subsp. stoechas. Tube dilution is one of the most frequently used methods for microbiological investigation. Its advantages are that it is easy to perform and provides information about minimum bactericidal concentration (MBC). Because of the lipophilic character of essential oils, the tube dilution method should be optimized for the detection of antibacterial activity of these plant extracts, and, therefore, emulsions containing 0.2% polysorbate 80 were prepared from the samples. In each of the eight investigated essential oils an inhibitory effect was detected, and MBC values were in the range 12.5-50 microL/mL in seven cases.
authors.affiliation: Central Clinical Pharmacy, Medical School, University of Pécs, 7624 Péics, Hungary.
authors.forename: Anna
authors.initials: A
authors.lastname: Végh
authors.forename: Tímea
authors.initials: T
authors.lastname: Bencsik
authors.forename: Péter
authors.initials: P
authors.lastname: Molnár
authors.forename: Andrea
authors.initials: A
authors.lastname: Böszörményi
authors.forename: Eva
authors.initials: E
authors.lastname: Lemberkovics
authors.forename: Krisztina
authors.initials: K
authors.lastname: Kovács
authors.forename: Béla
authors.initials: B
authors.lastname: Kocsis
authors.forename: Györgyi
authors.initials: G
authors.lastname: Horváth
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D008401:Gas Chromatography-Mass Spectrometry; D027523:Lavandula / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D013045:Species Specificity
chemical_list: D000900:Anti-Bacterial Agents; D009822:Oils, Volatile