title: Histones: sequestered by Jabba in fatty storehouse.
abstract: A paper in this issue shows that histones H2a and H2b are stored in lipid droplets in Drosophila embryos complexed with the protein Jabba. In Jabba mutant embryos, histones H2a and H2b are degraded but embryos survive by translating stored histone mRNA.
authors.affiliation: Department of Biochemistry, University of North Carolina at Chapel Hill School of Medicine, 208 Fordham Hall, Campus Box # 7100, Chapel Hill, NC 27599, USA. marzluff@med.unc.edu
authors.forename: William F
authors.initials: WF
authors.lastname: Marzluff
authors.forename: Deirdre C
authors.initials: DC
authors.lastname: Tatomer
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism; D004330:Drosophila / Q000196:embryology*; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental / Q000502:physiology; D006657:Histones / Q000378:metabolism*; D009154:Mutation; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism
chemical_list: D002352:Carrier Proteins; D029721:Drosophila Proteins; D006657:Histones; D012333:RNA, Messenger; C580936:jabba protein, Drosophila