title: Enzymatic synthesis of N-Acylethanolamines: Direct method for the aminolysis of esters.
abstract: Immobilized Candida antarctica (Novozyme 435) catalyzed synthesis of N-acylethanolamines is described. Treatment of methyl esters with lipase and amines yielded the desired amides within 2-24 hrs with yields ranging from 41-98%.
authors.affiliation: Center for Drug Discovery, 116 Mugar Hall, 360 Huntington Avenue, Northeastern University, Boston, MA 02115.
authors.forename: Kyle M
authors.initials: KM
authors.lastname: Whitten
authors.forename: Alexandros
authors.initials: A
authors.lastname: Makriyannis
authors.forename: Subramanian K
authors.initials: SK
authors.lastname: Vadivel