title: [Prostate-specific antigen bounce after permanent seed prostate brachytherapy: a literature review].
abstract: Permanent seeds brachytherapy is a standard in the treatment of localized prostate cancer. Follow-up of patients treated with brachytherapy relies on monitoring the concentration of PSA. It is supposed to decrease steadily to a nadir after several years. This decrease could be disrupted by transient and benign elevation of the marker, sometimes mimicking genuine biochemical relapses, sources of anxiety for patients or even unnecessary tests. While the precise mechanisms of this phenomenon are poorly understood, their characteristics have been, however, extensively studied. This work aims to make an update on the current state of knowledge.
authors.affiliation: Service de curiethérapie, département de radiothérapie, institut de cancérologie Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif cedex, France. renaud.mazeron@igr.fr
authors.forename: R
authors.initials: R
authors.lastname: Mazeron
authors.forename: A
authors.initials: A
authors.lastname: Bajard
authors.forename: P
authors.initials: P
authors.lastname: Pommier
mesh_terms: D000367:Age Factors; D000726:Androgen Antagonists / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D001918:Brachytherapy / Q000379:methods*; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood / Q000473:pathology / Q000532:radiotherapy*; D011879:Radiotherapy Dosage
chemical_list: D000726:Androgen Antagonists; D015415:Biomarkers; D017430:Prostate-Specific Antigen