title: [Research progress of extracellular matrix material for tissue engineering].
abstract: OBJECTIVE
  To review the current research status and clinical application progress of extracellular matrix (ECM) material in tissue engineering.
  
  
  METHODS
  The literature about the latest progress in the preparation, biocompatibility, mechanical property, degradability, and clinical application of ECM material was extensively reviewed.
  
  
  RESULTS
  The improvement of the ECM preparation method and thorough understanding of the immunological properties have laid the foundation for the repair and reconstruction of the tissue. Moreover, a series of animal studies also confirm that the feasibility and effectiveness of the ECM such as small intestinal submucosa, bladder ECM grift, and acellular dermis which have been applied to the repair and reconstruction of the urethra, bladder, arteries, and skin tissue. It shows a wide prospect of clinical application in the future.
  
  
  CONCLUSIONS
  ECM material is a good bio-derived scaffold, which is expected to become an important source of alternative materials for the repair and reconstruction of the tissue.
authors.affiliation: Department of Urology, West China Hospital, Sichuan University, Chengdu Sichuan 610041, PR China.
authors.forename: Haichao
authors.initials: H
authors.lastname: Yuan
authors.forename: Chunxiao
authors.initials: C
authors.lastname: Pu
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wei
authors.forename: Ping
authors.initials: P
authors.lastname: Han
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D002478:Cells, Cultured; D005109:Extracellular Matrix; D006801:Humans; D007413:Intestinal Mucosa / Q000166:cytology / Q000276:immunology / Q000637:transplantation; D007421:Intestine, Small; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds; D014570:Urologic Diseases / Q000601:surgery
chemical_list: D001672:Biocompatible Materials