title: Miscellaneous agents--cytotoxics and hormonal agents.
abstract: Among the 19 presentations of miscellaneous new agents at this year's meeting, several described novel cytotoxics and hormonal agents. The cytotoxic agents included microtubule inhibitors (eribulin, nanoparticle albumin-bound paclitaxel, peptide-bound paclitaxel), a topoisomerase inhibitor (nanoirinotecan), and an alkylating agent (palifosfamide). Hormonal agents included an aromatase inhibitor (anastrazole), an estrogen receptor antagonist (fulvestrant), and a selective androgen receptor modulator (GTx-024).
authors.affiliation: Department of Internal Medicine, Division of Hemtology-Oncology, Harold C Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA. david.gerber@utsouthwestern.edu
authors.forename: David E
authors.initials: DE
authors.lastname: Gerber
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003603:Cytotoxins / Q000627:therapeutic use*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D003603:Cytotoxins