title: Stereoselective total syntheses of (-)-flueggine A and (+)-virosaine B.
abstract: Convergent approach: the total syntheses of (-)-flueggine A and (+)-virosaine B have been accomplished in a concise and convergent manner. Key steps in these approaches were relay ring-closing metathesis reactions for rapid construction of the key intermediates, and 1,3-dipolar cycloaddition reactions for the formation of the natural products.
authors.affiliation: Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Wei
authors.forename: Chuang
authors.initials: C
authors.lastname: Qiao
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
authors.forename: Zhen
authors.initials: Z
authors.lastname: Yang
authors.forename: Chuang-chuang
authors.initials: CC
authors.lastname: Li
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis / Q000737:chemistry; D007212:Indolizines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D014326:Tropanes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001688:Biological Products; D007212:Indolizines; D014326:Tropanes; C568567:flueggine A; C576141:virosaine B