title: Systemic thromboembolism after anti-cancer chemotherapy in a woman with ovarian germ cell tumor.
abstract: A high cure rate of ovarian germ cell tumors was achieved by establishment of a cisplatin-containing regimen. We encountered a rare case of a 33-year-old, nulligravida Japanese woman with systemic thromboembolism following anti-cancer chemotherapy with cisplatin, etoposide, and bleomycin in ovarian germ cell tumor. She suffered from brain infarction, multiple embolisms in the bilateral pulmonary artery and pelvic vein, and a broad range of deep vein thromboses in the right extremities vein. When thrombosis is detected during anti-cancer chemotherapy, we must investigate whether the presence of thrombosis is systemic or local.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan. s-yana@m3.kufm.kagoshima-u.ac.jp
authors.forename: Shintaro
authors.initials: S
authors.lastname: Yanazume
authors.forename: Takahiro
authors.initials: T
authors.lastname: Tsuji
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsuo
authors.forename: Masaki
authors.initials: M
authors.lastname: Kamio
authors.forename: Sayori
authors.initials: S
authors.lastname: Terao
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Douchi
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D001761:Bleomycin / Q000008:administration & dosage / Q000009:adverse effects; D020520:Brain Infarction / Q000139:chemically induced*; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects; D005047:Etoposide / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D006801:Humans; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy*; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D013923:Thromboembolism / Q000139:chemically induced*
chemical_list: D000970:Antineoplastic Agents; D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin