title: Flow cytometry method as a diagnostic tool for pleural fluid involvement in a patient with multiple myeloma.
abstract: Multiple myeloma is a malignant proliferation of plasma cells that mainly affects bone marrow. Pleural effusions secondary to pleural myelomatous involvement have rarely been reported in the literature. As it is rarely detected, we aimed to report a case in which pleural effusion of a multiple myeloma was confirmed as true myelomatous involvement by flow cytometry method. A 52-years old man presented to our clinic with chest and back pain lasting for 3 months. On the chest radiography, pleural fluid was detected in left hemithorax. Pleural fluid flow cytometry was performed. In the flow cytometry, CD56, CD38 and CD138 found to be positive, while CD19 was negative. True myelomatous pleural effusions are very uncommon, with fewer than 100 cases reported worldwide. Flow cytometry is a potentially useful and simple method for detection of pleural fluid involvement in multiple myeloma.
authors.affiliation: Erciyes Stem Cell Transplantation Hospital, Department of Hematology, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
authors.forename: Muzaffer
authors.initials: M
authors.lastname: Keklik
authors.forename: Serdar
authors.initials: S
authors.lastname: Sivgin
authors.forename: Cigdem
authors.initials: C
authors.lastname: Pala
authors.forename: Celalettin
authors.initials: C
authors.lastname: Eroglu
authors.forename: Gulsah
authors.initials: G
authors.lastname: Akyol
authors.forename: Leylagul
authors.initials: L
authors.lastname: Kaynar
authors.forename: M Yavuz
authors.initials: MY
authors.lastname: Koker
authors.forename: Demet
authors.initials: D
authors.lastname: Camlica
authors.forename: Ali
authors.initials: A
authors.lastname: Unal
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cetin
authors.forename: Bulent
authors.initials: B
authors.lastname: Eser