title: Severe acute interstitial lung disease after crizotinib therapy in a patient with EML4-ALK-positive non-small-cell lung cancer.
authors.affiliation: Kinki-Chuo Chest Medical Center, Osaka, Japan.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Tamiya
authors.forename: Isamu
authors.initials: I
authors.lastname: Okamoto
authors.forename: Masaki
authors.initials: M
authors.lastname: Miyazaki
authors.forename: Shigeki
authors.initials: S
authors.lastname: Shimizu
authors.forename: Masanori
authors.initials: M
authors.lastname: Kitaichi
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Nakagawa
mesh_terms: D000208:Acute Disease; D000230:Adenocarcinoma / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D000328:Adult; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D000077547:Crizotinib; D017809:Fatal Outcome; D015321:Gene Rearrangement; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced* / Q000235:genetics / Q000473:pathology; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D008297:Male; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D047428:Protein Kinase Inhibitors / Q000009:adverse effects; D011720:Pyrazoles / Q000009:adverse effects*; D011725:Pyridines / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
chemical_list: C522504:EML4-ALK fusion protein, human; D015514:Oncogene Proteins, Fusion; D047428:Protein Kinase Inhibitors; D011720:Pyrazoles; D011725:Pyridines; D000077547:Crizotinib