title: A new 20-membered macrolide produced by a marine-derived Micromonospora strain.
abstract: A new 20-membered macrolide named as levantilide C was isolated from the Micromonospora strain FIM07-0019 recovered from shallow coastal waters near the island of Chiloe, Chile. The chemical structure of levantilide C was elucidated on the basis of one- and two-dimensional NMR analysis. Two known indole derivatives were also isolated from this strain. Levantilide C exhibited moderate antiproliferative activity against several tumour cell lines.
authors.affiliation: Fujian Key Laboratory of Screening for Novel Microbial Products, Fujian Institute of Microbiology, Fuzhou, P.R. China.
authors.forename: Peng
authors.initials: P
authors.lastname: Fei
authors.forename: Wang
authors.initials: W
authors.lastname: Chuan-Xi
authors.forename: Xie
authors.initials: X
authors.lastname: Yang
authors.forename: Jiang
authors.initials: J
authors.lastname: Hong-Lei
authors.forename: Chen
authors.initials: C
authors.lastname: Lu-Jie
authors.forename: Paulina
authors.initials: P
authors.lastname: Uribe
authors.forename: Alan T
authors.initials: AT
authors.lastname: Bull
authors.forename: Michael
authors.initials: M
authors.lastname: Goodfellow
authors.forename: Jiang
authors.initials: J
authors.lastname: Hong
authors.forename: Lian
authors.initials: L
authors.lastname: Yun-Yang
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002677:Chile; D006801:Humans; D018942:Macrolides / Q000737:chemistry* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008847:Micromonospora / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D018942:Macrolides