title: Spinal anesthesia with low-dose bupivacaine-fentanyl combination: a good alternative for day case transurethral resection of prostrate surgery in geriatric patients.
abstract: OBJECTIVE
  We evaluated the effectiveness, block duration, postanesthesia care unit stay and adverse effects of using intrathecal low dose bupivacaine and fentanyl combination and compared with conventional dose prilocaine and fentanyl combination for day case transurethral resection of prostate surgery in geriatric patient population.
  
  
  METHODS
  Sixty patients were randomized into two groups with Group B receiving 4 mg bupivacine 0.5%+25 μg fentanyl and Group P receiving 50 mg prilocaine 2%+25 μg fentanyl intrathecal. Block quality and duration, postanesthesia care unit stay and adverse effects were compared.
  
  
  RESULTS
  Block durations and postanesthesia care unit stay were shorter in Group B than in Group P (p<0.001 in both). Hypotension and bradycardia were not seen in Group B which was significantly different than in Group P (p=0.024 and p=0.011 respectively).
  
  
  CONCLUSIONS
  Intrathecal 4 mg bupivacaine + 25 μg fentanyl provided adequate spinal anesthesia with shorter block duration and postanesthesia care unit stay with stable hemodynamic profile than intrathecal 50 mg prilocaine + 25 μg fentanyl for day case transurethral resection of prostate surgery in geriatric patients.
authors.affiliation: Department of Anesthesiology, Ankara Numune Training and Research Hospital, Ankara, Turkey. zakcaboy@yahoo.com
authors.forename: Zeynep N
authors.initials: ZN
authors.lastname: Akcaboy
authors.forename: Erkan Y
authors.initials: EY
authors.lastname: Akcaboy
authors.forename: Nevzat M
authors.initials: NM
authors.lastname: Mutlu
authors.forename: Nurten
authors.initials: N
authors.lastname: Serger
authors.forename: Cuneyt
authors.initials: C
authors.lastname: Aksu
authors.forename: Nermin
authors.initials: N
authors.lastname: Gogus
mesh_terms: D000368:Aged; D000556:Ambulatory Surgical Procedures; D000775:Anesthesia, Spinal; D019162:Anesthetics, Combined / Q000008:administration & dosage*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D004311:Double-Blind Method; D005283:Fentanyl / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D011318:Prilocaine / Q000008:administration & dosage*; D011446:Prospective Studies; D020728:Transurethral Resection of Prostate
chemical_list: D019162:Anesthetics, Combined; D018686:Anesthetics, Intravenous; D000779:Anesthetics, Local; D011318:Prilocaine; D005283:Fentanyl; D002045:Bupivacaine