title: Frequency of human bocavirus respiratory infections among at-risk patients in São Paulo, Brazil.
abstract: OBJECTIVE
  Human Bocavirus (HBoV) has been described since 2005 as an etiological agent of respiratory virus infections. From 2001 to 2008 we investigated the etiology of HBoV among adults and children in different groups at risk of presenting complications arising from acute respiratory infection, the investigation was carried out in a tertiary hospital health care system in Brazil.
  
  
  METHODS
  HBoV DNA was assayed in 598 respiratory samples from community and hospitalized patients by PCR.
  
  
  RESULTS
  Of the 598 tested samples, 2.44% (8/328) of children, including five children with heart disease, and 0.4% (1/270) of adult bone-marrow-transplant were HBoV positive.
  
  
  CONCLUSIONS
  These data suggested lower HBoV frequency among different at-risk patients and highlights the need to better understand the real role of HBoV among acute respiratory symptomatic patients.
authors.affiliation: Clinical Virology Laboratory, Infectious Diseases Unit, Medicine Department, Sao Paulo Federal University, Sao Paulo, Brazil. aripuana77@hotmail.com
authors.forename: Elaine Regina Baptista
authors.initials: ER
authors.lastname: Caccia
authors.forename: Aripuana Sakurada Aranha
authors.initials: AS
authors.lastname: Watanabe
authors.forename: Emerson
authors.initials: E
authors.lastname: Carraro
authors.forename: Elcio
authors.initials: E
authors.lastname: Leal
authors.forename: Celso
authors.initials: C
authors.lastname: Granato
authors.forename: Nancy
authors.initials: N
authors.lastname: Bellei
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004279:DNA, Viral / Q000032:analysis* / Q000235:genetics; D056661:Human bocavirus / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D010322:Parvoviridae Infections / Q000175:diagnosis / Q000453:epidemiology*; D016133:Polymerase Chain Reaction; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D012307:Risk Factors; D012621:Seasons; D055815:Young Adult
chemical_list: D004279:DNA, Viral