title: Comparative study of the antimicrobial effect of three irrigant solutions (chlorhexidine, sodium hypochlorite and chlorhexidinated MUMS).
abstract: OBJECTIVE
  To compare the antimicrobial effect of 2% chlorhexidine, 2.5% sodium hypochlorite and MUMS containing 2% chlorhexidine.
  
  
  METHODS
  All of the above irrigants were examined on Enterococcus faecalis, Streptococcus mutans, Candida albicans, Lactobacillus casei and E. coli. A total of 0.5 CC of each solution and 0.5 CC of McFarland solution bacterium were added to each examination tube. After 15, 30 and 45 minutes, colony count was performed for each tube. The difference in the number of bacteria indicated the effect taken by disinfectant material.
  
  
  RESULTS
  MUMS containing chlorhexidine showed the antimicrobial properties just like chlorhexidine's effect against E. coli, Streptococcus mutans, Candida albicans, Enterococcus faecalis and Lactobacillus casei in preventing these entire microorganisms to incubate. Sodium hypochlorite was not effective against Enterococcus faecalis and Candida albicans incubated in 15, 30 and 45 minutes and Enterococcus faecalis in 15 minutes.
  
  
  CONCLUSIONS
  MUMS has antimicrobial properties similar to chlorhexidine.
  
  
  CONCLUSIONS
  As MUMS containing chlorhexidine can transfer chlorhexidine through its own surfactant around apical area and it can open the dentinal tubules by its own chelator for more penetration of chlorhexidine, it may be a choice for canal irrigation.
authors.affiliation: Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Bidar
authors.forename: Sepideh
authors.initials: S
authors.lastname: Hooshiar
authors.forename: Mahboubeh
authors.initials: M
authors.lastname: Naderinasab
authors.forename: Mostafa
authors.initials: M
authors.lastname: Moazzami
authors.forename: Hossein
authors.initials: H
authors.lastname: Orafaee
authors.forename: Neda
authors.initials: N
authors.lastname: Naghavi
authors.forename: Hamid
authors.initials: H
authors.lastname: Jafarzadeh
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects*; D002710:Chlorhexidine / Q000494:pharmacology; D015169:Colony Count, Microbial; D004492:Edetic Acid / Q000494:pharmacology; D013293:Enterococcus faecalis / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D006601:Hexoses / Q000494:pharmacology; D007780:Lacticaseibacillus casei / Q000187:drug effects; D011136:Polysorbates / Q000494:pharmacology; D012388:Root Canal Irrigants / Q000737:chemistry* / Q000494:pharmacology*; D012973:Sodium Hypochlorite / Q000494:pharmacology; D013295:Streptococcus mutans / Q000187:drug effects
chemical_list: D006601:Hexoses; D011136:Polysorbates; D012388:Root Canal Irrigants; C018665:sorbitan monooleate; D004492:Edetic Acid; D012973:Sodium Hypochlorite; D002710:Chlorhexidine