title: Three novel immunosuppressive steroidal glycosides from the stems of Stephanotis mucronata.
abstract: Three novel and one known C21 steroidal glycosides were isolated from the stems of Stephanotis mucronata. Their structures were determined on the basis of chemical evidence and extensive spectroscopic methods. The four C21 steroidal glycosides displayed significant immunosuppressive activities in vitro.
authors.affiliation: Institute of Materia Medica, Zhejiang Academy of Medical Sciences, Hangzhou, 310013, P.R. China.
authors.forename: Xiao-Yu
authors.initials: XY
authors.lastname: Li
authors.forename: Shu-Ling
authors.initials: SL
authors.lastname: Zong
authors.forename: Feng-Yang
authors.initials: FY
authors.lastname: Chen
authors.forename: Shi-Fang
authors.initials: SF
authors.lastname: Xu
authors.forename: Yi-Ping
authors.initials: YP
authors.lastname: Ye
mesh_terms: D000818:Animals; D029062:Apocynaceae / Q000737:chemistry*; D049109:Cell Proliferation / Q000187:drug effects; D002855:Chromatography, Thin Layer; D003208:Concanavalin A / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D006027:Glycosides / Q000302:isolation & purification / Q000494:pharmacology*; D007166:Immunosuppressive Agents / Q000302:isolation & purification / Q000494:pharmacology*; D008070:Lipopolysaccharides / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051379:Mice; D018547:Plant Stems / Q000737:chemistry; D013154:Spleen / Q000187:drug effects / Q000276:immunology; D013256:Steroids / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D006027:Glycosides; D007166:Immunosuppressive Agents; D008070:Lipopolysaccharides; D013256:Steroids; D003208:Concanavalin A