title: Preliminary results in the redox balance in healthy cats: influence of age and gender.
abstract: Oxidative stress (OS) impairs organic function and is considered causally related to cellular senescence and death. This study aims to evaluate if the redox balance varies in relation to age and gender in healthy cats. To quantify the oxidative status of this species we determined the oxidative damage as serum reactive oxygen metabolites (ROM) and the total serum antioxidant capacity (SAC). In addition, we used the ratio of ROM to SAC as a measure of the oxidative balance, with higher values meaning higher oxidative stress (oxidative stress index). Our results suggest that the male population is at oxidative risk when compared with females, especially between the age of 2 and 7 years. Nutritional strategies in this population looking for additional antioxidant support would probably avoid the oxidative stress status that predisposes to chronic processes in senior male cats. Further clinical trials in this field are recommended.
authors.affiliation: Animal Pathology Department, Veterinary Faculty of Lugo, University of Santiago de Compostela, Lugo, Spain. cristina.castillo@usc.es
authors.forename: Cristina
authors.initials: C
authors.lastname: Castillo
authors.forename: Victor
authors.initials: V
authors.lastname: Pereira
authors.forename: Angel
authors.initials: A
authors.lastname: Abuelo
authors.forename: Rebeca
authors.initials: R
authors.lastname: Guimarey
authors.forename: Marco
authors.initials: M
authors.lastname: García-Vaquero
authors.forename: José L
authors.initials: JL
authors.lastname: Benedito
authors.forename: Joaquín
authors.initials: J
authors.lastname: Hernández
mesh_terms: D000818:Animals; D002415:Cats / Q000502:physiology*; D005260:Female; D008297:Male; D009752:Nutritional Status; D010084:Oxidation-Reduction; D018384:Oxidative Stress / Q000502:physiology; D017382:Reactive Oxygen Species / Q000378:metabolism*; D012016:Reference Values; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D017382:Reactive Oxygen Species