title: Recent advances in radiofrequency ablation for the management of hepatocellular carcinoma.
abstract: CONTEXTS: Hepatocellular carcinoma (HCC) is one of the most common malignant diseases in the world. Because less than 20% of patients with HCC are resectable, various types of non-surgical treatment have been developed.
  
  
  METHODS
  At present, radiofrequency ablation (RFA) is accepted as the standard local treatment for patients with HCC because of its superior local control and overall survival compared to other local treatments.
  
  
  RESULTS
  New devices for RFA and combination treatments of RFA with other procedures have been developed to improve anti-tumoral effects.
  
  
  CONCLUSIONS
  This review mainly focuses on the status of RFA in the management of HCC and recent advances in RFA treatment technology.
authors.affiliation: Department of Integrated Medicine, Kagawa, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Himoto
authors.forename: Kazutaka
authors.initials: K
authors.lastname: Kurokohchi
authors.forename: Seishiro
authors.initials: S
authors.lastname: Watanabe
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Masaki