title: A comparative evaluation of the healing ability of bilateral periapical lesions treated with and without the use of platelet-rich fibrin.
abstract: Periradicular surgery aims to achieve complete wound healing and regeneration of the periodontal unit. Platelet-rich fibrin (PRF) is a platelet concentrate that is widely used to promote tissue healing and bone induction through its various growth factors and has been used in this study. This case report describes the use of PRF unilaterally in a bilateral periapical lesion in the same patient. The site treated with PRF showed better healing than the other site. This was confirmed with a 3-D X-ray.
authors.affiliation: SPDC, USA. dnbambal@gmail.com
authors.forename: Dhanashri
authors.initials: D
authors.lastname: Bambal
authors.forename: N U
authors.initials: NU
authors.lastname: Manwar
authors.forename: Manoj
authors.initials: M
authors.lastname: Chandak
authors.forename: Kavitarani
authors.initials: K
authors.lastname: Rudagi
mesh_terms: D000328:Adult; D001792:Blood Platelets; D001861:Bone Regeneration / Q000187:drug effects*; D005337:Fibrin / Q000494:pharmacology*; D006801:Humans; D008297:Male; D010485:Periapical Periodontitis / Q000601:surgery*; D010982:Platelet-Derived Growth Factor / Q000494:pharmacology; D012184:Retrograde Obturation; D016212:Transforming Growth Factor beta / Q000494:pharmacology; D042461:Vascular Endothelial Growth Factor A / Q000494:pharmacology
chemical_list: D010982:Platelet-Derived Growth Factor; D016212:Transforming Growth Factor beta; D042461:Vascular Endothelial Growth Factor A; D005337:Fibrin