title: A case of ulcerative colitis complicated with bronchiolitis obliterans organizing pneumonia (BOOP) and air leak syndrome.
abstract: Extraintestinal manifestations of inflammatory bowel diseases are well recognized and mainly affect the joints, skin, liver, and eyes; however, clinically significant pulmonary involvement is very rare. Early identification of pulmonary involvement is important and will be life-saving. We report herein a case of an ulcerative colitis patient, presenting with acute respiratory distress syndrome and bilateral recurring pneumothorax, pneumomediastinum and subcutaneous emphysema, i.e., air leak syndrome. He was diagnosed with open lung biopsy as bronchiolitis obliterans organizing pneumonia most probably due to viral etiology and responded well to steroid therapy, with almost complete resolution of radiographic and clinical findings. In inflammatory bowel disease patients, bronchiolitis obliterans organizing pneumonia developing due to viral or fungal infectious etiology or due to the inflammatory bowel disease itself may progress to acute respiratory distress syndrome and may present with air leak syndrome. Early detection is important and life-saving, since bronchiolitis obliterans organizing pneumonia often responds well to steroid treatment provided an infectious etiology has been excluded or adequate antimicrobial therapy has already been initiated.
authors.affiliation: University of Gazi, School of Medicine, Pulmonary Diseases Department and Intensive Care Unit, Ankara, Turkey. mugeaydogdu@yahoo.com
authors.forename: Müge
authors.initials: M
authors.lastname: Aydoğdu
authors.forename: Gül
authors.initials: G
authors.lastname: Gürsel
authors.forename: Ezgi
authors.initials: E
authors.lastname: Özyilmaz
authors.forename: Nalan
authors.initials: N
authors.lastname: Akyürek
authors.forename: Leyla
authors.initials: L
authors.lastname: Memış
mesh_terms: D001999:Bronchoscopy; D003093:Colitis, Ulcerative / Q000150:complications* / Q000175:diagnosis; D003113:Colonoscopy; D018549:Cryptogenic Organizing Pneumonia / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008478:Mediastinal Emphysema / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged; D011030:Pneumothorax / Q000150:complications* / Q000175:diagnosis; D012128:Respiratory Distress Syndrome / Q000175:diagnosis / Q000209:etiology*; D013352:Subcutaneous Emphysema / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed