title: Depsides and triterpenes in Pseudocyphellaria coriifolia (lichens) and biological activity against Trypanosoma cruzi.
abstract: The lichen Pseudocyphellaria coriifolia is a species endemic to southern South America. From the lichen thallus, methyl evernate, tenuiorin and three hopane triterpenoids were isolated and identified as the main lichen constituents. Their trypanocidal effects were screened against epimastigotes of Trypanosoma cruzi. The results of the biological test showed that some hopane terpenoids exhibit antiparasitic properties.
authors.affiliation: Facultad de Farmacia, Universidad de Valparaíso, Av. Gran Bretaña N 1093, Valparaíso, Chile. mauricio.cuellar@uv.cl
authors.forename: Mauricio Cuellar
authors.initials: MC
authors.lastname: Fritis
authors.forename: Cecilia Rubio
authors.initials: CR
authors.lastname: Lagos
authors.forename: Natalia Quiñones
authors.initials: NQ
authors.lastname: Sobarzo
authors.forename: Iván Montenegro
authors.initials: IM
authors.lastname: Venegas
authors.forename: Cristian Salas
authors.initials: CS
authors.lastname: Sánchez
authors.forename: Hector Carrasco
authors.initials: HC
authors.lastname: Altamirano
authors.forename: Luis Espinoza
authors.initials: LE
authors.lastname: Catalán
authors.forename: Wanda Quilhot
authors.initials: WQ
authors.lastname: Palma
mesh_terms: D053630:Depsides / Q000737:chemistry* / Q000494:pharmacology; D008011:Lichens / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry* / Q000494:pharmacology; D014344:Trypanocidal Agents / Q000737:chemistry* / Q000494:pharmacology*; D014349:Trypanosoma cruzi / Q000187:drug effects
chemical_list: D053630:Depsides; D014315:Triterpenes; D014344:Trypanocidal Agents