title: Improved accuracy of cytodiagnosis using the Kato self-collection devise: the usefulness of smear preparation in liquid-based cytology methods.
abstract: OBJECTIVE
  In the present study, we compared the positive cytodiagnostic test rates with discrepancies using self-collection devices for cervical cancer screening. We made this survey to examine whether or not our self- smear preparation method using the Kato self-collection device contributed to an improved rate of detecting atypical cells compared with existing recommended preparation methods.
  
  
  METHODS
  Specimens were collected at 14 facilities handling self-collection methods, and samples were collected by a physician in 2 facilities. The chi- squared test was performed using the SPSS ver. 20 statistical software to determine the relationships between the positive cytodiagnostic rate, specimen preparation methods, and self-collection devices.
  
  
  RESULTS
  Collecting cells using the Kato self-collection device and preparing liquid-based specimens, we obtained a significantly higher rate of positive cytodiagnosis and our results were equal to those obtained with the direct method.
  
  
  CONCLUSIONS
  Taking into consideration increased needs for screening using the self-collection method in future, with even more improved test accuracy, a screening test that is acceptable to society needs to be established.
authors.affiliation: Department of Pathology, Faculty of Health Sciences, Kyorin University, Tokyo, Japan. okayaman0811@std.kyorin-u.ac.jp
authors.forename: Kaori
authors.initials: K
authors.lastname: Okayama
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Okodo
authors.forename: Masahiko
authors.initials: M
authors.lastname: Fujii
authors.forename: Tomoko
authors.initials: T
authors.lastname: Kumagai
authors.forename: Hiromi
authors.initials: H
authors.lastname: Yabusaki
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Shiina
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Iwami
authors.forename: Koji
authors.initials: K
authors.lastname: Teruya
authors.forename: Kenmei
authors.initials: K
authors.lastname: Hatta
mesh_terms: D016009:Chi-Square Distribution; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D012648:Self Care / Q000295:instrumentation; D013048:Specimen Handling / Q000295:instrumentation* / Q000379:methods; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis*; D014626:Vaginal Smears / Q000295:instrumentation* / Q000592:standards; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis*