title: The relationship between carotid intima-media thickness and endogenous androgens in young women with polycystic ovary syndrome in Taiwan.
abstract: Polycystic ovary syndrome (PCOS) is a common and complex female endocrinopathy that is associated with multiple vascular risk factors. Our objective was to investigate the relationship between carotid intima-media thickness (CIMT) and endogenous androgens in young Taiwanese-Chinese women with PCOS. We measured CIMT with B-mode ultrasound in 42 young PCOS patients and 43 controls. Atherosclerosis-associated profiles and endocrinological parameters were also measured. The results showed that although Taiwanese-Chinese PCOS patients tend to possess more risk factors for atherosclerosis than controls, there was no evidence to support that they have a greater CIMT at this age. Furthermore, androstenedione appears to be inversely associated with CIMT.
authors.affiliation: Department of Neurology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
authors.forename: Hao-Wen
authors.initials: HW
authors.lastname: Teng
authors.forename: Yi-Wen
authors.initials: YW
authors.lastname: Chien
authors.forename: Ming-I
authors.initials: MI
authors.lastname: Hsu
authors.forename: Chin-I
authors.initials: CI
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000728:Androgens / Q000097:blood*; D000735:Androstenedione / Q000097:blood; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000473:pathology*; D059168:Carotid Intima-Media Thickness; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008599:Menstruation Disturbances / Q000208:ethnology / Q000209:etiology; D011085:Polycystic Ovary Syndrome / Q000097:blood* / Q000208:ethnology / Q000473:pathology* / Q000503:physiopathology; D012044:Regression Analysis; D012307:Risk Factors; D013624:Taiwan / Q000453:epidemiology; D014652:Vascular Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000208:ethnology / Q000209:etiology; D055815:Young Adult
chemical_list: D000728:Androgens; D000735:Androstenedione