title: Palladium-catalyzed reactions of enol ethers: access to enals, furans, and dihydrofurans.
abstract: The palladium-catalyzed oxidation of alkyl enol ethers to enals, which employs low loadings of a palladium catalyst, is described. The mild oxidation conditions tolerate a diverse array of functional groups, while allowing the formation of di-, tri-, and tetrasubtituted olefins. The application of this methodology to intramolecular reactions of alkyl enol ethers containing pendant alcohols provides furan and 2,5-dihydrofuran products.
authors.affiliation: Evans Chemical Laboratories, Department of Chemistry, The Ohio State University, 100 West 18th Avenue, Columbus, Ohio 43210, USA.
authors.forename: Matthew G
authors.initials: MG
authors.lastname: Lauer
authors.forename: William H
authors.initials: WH
authors.lastname: Henderson
authors.forename: Amneh
authors.initials: A
authors.lastname: Awad
authors.forename: James P
authors.initials: JP
authors.lastname: Stambuli