title: Profile and geographic distribution of reported cases of visceral leishmaniasis in Campo Grande, State of Mato Grosso do Sul, Brazil, from 2002 to 2009.
abstract: BACKGROUND
  This study sought to describe the profile and geographic distribution of reported cases of visceral leishmaniasis (VL) in the City of Campo Grande, State of Mato Grosso do Sul (MS), Brazil, from 2002 to 2009.
  
  
  METHODS
  Human data were collected from the Brazilian National Information System for Notifiable Diseases. Canine cases and entomological data were obtained from the Information Service for Canine Visceral Leishmaniasis Control/Campo Grande, MS.
  
  
  RESULTS
  A total of 951 records from 2002 to 2009 were investigated. The number of reported cases of VL in males was significantly higher (p < 0.0001) than that in females. The higher frequency observed among males was associated with age (p < 0.0001), which increased in individuals aged 40 years and older. The overall fatality rate was 7.4%. Entomological surveys conducted in 2006, 2007, and 2009 showed the insect vector Lutzomyia longipalpis to be present in all urban regions of the county.
  
  
  CONCLUSIONS
  VL cases in humans and dogs, as well as in vectors, occurs in all urban regions of Campo Grande. Despite not observing tendencies of increase or reduction in the incidence of the disease due to aging, the major incidence in men is higher in those aged 40 years or above.
authors.affiliation: Programa de Pós-Graduação em Doenças Infecciosas e Parasitárias, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil. maksoudbrazuna@gmail.com
authors.forename: Júlia Cristina Maksoud
authors.initials: JC
authors.lastname: Brazuna
authors.forename: Elaine Araujo E
authors.initials: EA
authors.lastname: Silva
authors.forename: Júlio Maksoud
authors.initials: JM
authors.lastname: Brazuna
authors.forename: Iara Helena
authors.initials: IH
authors.lastname: Domingos
authors.forename: Neuma
authors.initials: N
authors.lastname: Chaves
authors.forename: Michael Robin
authors.initials: MR
authors.lastname: Honer
authors.forename: Valter Joost
authors.initials: VJ
authors.lastname: van Onselen
authors.forename: Ana Lúcia Lyrio de
authors.initials: AL
authors.lastname: Oliveira
mesh_terms: D017677:Age Distribution; D000818:Animals; D001938:Brazil / Q000453:epidemiology; D004283:Dog Diseases / Q000453:epidemiology* / Q000469:parasitology; D004285:Dogs; D005260:Female; D006801:Humans; D015994:Incidence; D007303:Insect Vectors / Q000469:parasitology*; D007898:Leishmaniasis, Visceral / Q000453:epidemiology / Q000635:transmission* / Q000662:veterinary*; D008297:Male; D011576:Psychodidae / Q000469:parasitology*; D012189:Retrospective Studies; D017678:Sex Distribution; D012959:Socioeconomic Factors