title: Genome-wide survey and expression analysis of amino acid transporter gene family in rice (Oryza sativa L.).
abstract: BACKGROUND
  Amino acid transporters (AATs) that transport amino acids across cellular membranes are essential for plant growth and development. To date, a genome-wide overview of the AAT gene family in rice is not yet available.
  
  
  RESULTS
  In this study, a total of 85 AAT genes were identified in rice genome and were classified into eleven distinct subfamilies based upon their sequence composition and phylogenetic relationship. A large number of OsAAT genes were expanded via gene duplication, 23 and 24 OsAAT genes were tandemly and segmentally duplicated, respectively. Comprehensive analyses were performed to investigate the expression profiles of OsAAT genes in various stages of vegetative and reproductive development by using data from EST, Microarrays, MPSS and Real-time PCR. Many OsAAT genes exhibited abundant and tissue-specific expression patterns. Moreover, 21 OsAAT genes were found to be differentially expressed under the treatments of abiotic stresses. Comparative analysis indicates that 26 AAT genes with close evolutionary relationships between rice and Arabidopsis exhibited similar expression patterns.
  
  
  CONCLUSIONS
  This study will facilitate further studies on OsAAT family and provide useful clues for functional validation of OsAATs.
authors.affiliation: State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, China.
authors.forename: Heming
authors.initials: H
authors.lastname: Zhao
authors.forename: Haoli
authors.initials: H
authors.lastname: Ma
authors.forename: Li
authors.initials: L
authors.lastname: Yu
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Jie
authors.initials: J
authors.lastname: Zhao
mesh_terms: D000595:Amino Acid Sequence; D026905:Amino Acid Transport Systems / Q000235:genetics* / Q000378:metabolism*; D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism; D002874:Chromosome Mapping; D019295:Computational Biology; D020869:Gene Expression Profiling; D018506:Gene Expression Regulation, Plant / Q000502:physiology*; D020131:Genes, Duplicate / Q000235:genetics; D023281:Genomics; D046228:Microarray Analysis; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000235:genetics*; D012275:Oryza / Q000235:genetics*; D010802:Phylogeny; D060888:Real-Time Polymerase Chain Reaction; D016415:Sequence Alignment; D013045:Species Specificity; D013312:Stress, Physiological / Q000235:genetics
chemical_list: D026905:Amino Acid Transport Systems