title: Advances in modifying fluorescein and rhodamine fluorophores as fluorescent chemosensors.
abstract: The fluorophores based on xanthene scaffolds, mainly containing rhodamine and fluorescein dyes, have attracted considerable interest from chemists due to their excellent photophysical properties such as high absorption coefficient, high fluorescence quantum yield, high photostability and relatively long wavelengths of fluorescence emission spectra. In this feature article, we overview the strategies in the development of fluorescent probes that are operating through the modification of the skeletons of fluorescein and rhodamine dyes, and the fluorescent behaviors of these probes toward specific analyte are discussed.
authors.affiliation: Department of Chemistry, College of Chemistry and Chemical Engineering, and the MOE Key Laboratory of Analytical Sciences, Xiamen University, Xiamen 361005, China. hzheng@xmu.edu.cn
authors.forename: Hong
authors.initials: H
authors.lastname: Zheng
authors.forename: Xin-Qi
authors.initials: XQ
authors.lastname: Zhan
authors.forename: Qing-Na
authors.initials: QN
authors.lastname: Bian
authors.forename: Xiao-Juan
authors.initials: XJ
authors.lastname: Zhang
mesh_terms: D019793:Fluorescein / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D014966:Xanthenes / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D012235:Rhodamines; D014966:Xanthenes; D019793:Fluorescein