title: Safe handling and administration considerations of oral anticancer agents in the clinical and home setting.
abstract: The use of hormonal, chemotherapeutic, and targeted biologic oral agents has exponentially increased since the early 2000s. Oral therapies have the advantage of persistent exposure of the cytotoxic drug to tumor cells and the tumor environment. The use of oral anticancer agents provides therapeutic drug treatment for patients with cancer in the comfort of their home or alternative settings, such as retirement homes and assisted living or extended-care facilities. Practices to ensure safe storage, handling, administration, and disposal of oral agents are necessary to prevent additional exposure of hazardous substances to the environment, professionals, patients, family members, and caretakers. Providers should consider potential barriers to adherence and compliance, and develop strategies to ensure optimal therapeutic benefit prior to initiation of oral agents.
authors.affiliation: Department of Nursing Research at Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital, USA. joanne.lester@osumc.edu
authors.forename: Joanne
authors.initials: J
authors.lastname: Lester
mesh_terms: D000284:Administration, Oral; D000554:Ambulatory Care Facilities; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D019983:Guideline Adherence; D006699:Home Care Services; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000451:nursing; D010349:Patient Compliance
chemical_list: D000970:Antineoplastic Agents