title: Chemical constituents from stem bark and roots of Clausena anisata.
abstract: Phytochemical investigations on the stem bark and roots of the tropical shrub Clausena anisata led to the isolation and characterization three carbazole alkaloids: girinimbine, murrayamine-A and ekeberginine; two peptide derivatives: aurantiamide acetate and N-benzoyl-L-phenylalaninyl-N-benzoyl-L-phenylalaninate; and a mixture of two phytosterols: sitosterol and stigmasterol. The structures of these compounds were established by nuclear magnetic resonance (1H-NMR, 13C-NMR, COSY, HSQC, HMQC, HMBC and NOESY) spectroscopy and electrospray ionization mass spectrometry (MS).
authors.affiliation: Department of Chemistry, University of Douala, Cameroon, P.O. Box 24157, Douala, Cameroon. lobejules@yahoo.fr
authors.forename: Jules Lobe
authors.initials: JL
authors.lastname: Songue
authors.lastname: Kouam
authors.forename: Etienne
authors.initials: E
authors.lastname: Dongo
authors.forename: Theophile Ngando
authors.initials: TN
authors.lastname: Mpondo
authors.forename: Robert L
authors.initials: RL
authors.lastname: White
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification; D002227:Carbazoles / Q000737:chemistry / Q000302:isolation & purification; D054700:Clausena / Q000737:chemistry*; D004151:Dipeptides / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010840:Phytosterols / Q000737:chemistry / Q000302:isolation & purification; D024301:Plant Bark / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification; D018517:Plant Roots / Q000737:chemistry*; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D000470:Alkaloids; D002227:Carbazoles; D004151:Dipeptides; D010840:Phytosterols; D010936:Plant Extracts; C034052:girinimbine; C011670:N-benzoylphenylalanylphenylalinol acetate