title: [Postoperative evolution of pulmonary arterial hypertension associated with patent ductus arteriosus at an altitude of 2680 meters above sea level].
abstract: BACKGROUND
  Patent ductus arteriosus in Toluca can cause pulmonary hypertension and ranks first surgery of congenital heart disease in Toluca, Mexico.
  
  
  METHODS
  In the period between January 2006 and December 51 patients with patent ductus arteriosus went to surgery: 34 (66.7%) were female. We study the reversibility of pulmonary arterial pressure and the left cavities dilatation after surgical closure of the ductus arteriosus and postoperative complications are described in a population of Toluca, located at an altitude of 2680 meters over the sea.
  
  
  RESULTS
  The reversibility of pulmonary pressure ocurred in 88% of cases. We also observed a decrease in the diameters of the left chambers manifested by a ratio of left atrium/aortic annulus before surgery of 2.0 ± 0.41 SD and after surgery of 1.36 ± 0.25 SD, (p<0.001). The successful closure of the ductus arteriosus was 94.1% immediately and mediate 98.0%. Postoperative complications ocurred in 13.8%, being the main infection and surgical wound hematoma (5.9%), pneumothorax (3.9%), pneumonia (2.0%) and pleural efusion (2.0%).
  
  
  CONCLUSIONS
  Pulmonary arterial hypertension secundary to patent ductus arteriosus is reversible in the mayority of cases after surgical closure, including residents of village above 2500 meters over the sea.
authors.affiliation: Departamento de Pediatría, Hospital Materno Infantil, Instituto Mexicano del Seguro Social del Estado de México y Municipios (ISSEMyM), Toluca, México.
authors.forename: Jorge Alberto
authors.initials: JA
authors.lastname: Morales-Quispe
authors.forename: Nilda
authors.initials: N
authors.lastname: Espinola-Zavaleta
authors.forename: Rocío
authors.initials: R
authors.lastname: Caballero-Caballero
authors.forename: Laura Elizabeth
authors.initials: LE
authors.lastname: Merino-Pasaye
authors.forename: Alejandro
authors.initials: A
authors.lastname: Solano-Gutierrez
authors.forename: Fernando
authors.initials: F
authors.lastname: Rodríguez-Ortega
mesh_terms: D000531:Altitude; D002675:Child, Preschool; D004374:Ductus Arteriosus, Patent / Q000150:complications* / Q000601:surgery*; D065627:Familial Primary Pulmonary Hypertension; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008800:Mexico; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology