title: MRI in OA: from cartilage to bone marrow lesion.
abstract: In contrast to radiography, magnetic resonance imaging permits visualization of all articular structures affected by osteoarthritis. Many studies have demonstrated its potential to elucidate the pathophysiological phenomena that lead to joint destruction, quantify cartilage damage, and establish risk factors for chondrolysis. Bone marrow lesion is a well-recognized process localized just beneath the subchondral bone that is responsible for clinical symptoms and structural changes not only to bone but also to cartilage.
authors.affiliation: Service de Rhumatologie, CHU Nancy Brabois, rue du Morvan, 54500, Vandoeuvre-lès-Nancy, France. d.loeuille@chu-nancy.fr
authors.forename: D
authors.initials: D
authors.lastname: Loeuille
authors.forename: I
authors.initials: I
authors.lastname: Chary-Valckenaere
mesh_terms: D000818:Animals; D050071:Bone Density Conservation Agents / Q000494:pharmacology; D001853:Bone Marrow / Q000187:drug effects / Q000473:pathology*; D001855:Bone Marrow Diseases / Q000175:diagnosis / Q000209:etiology; D002358:Cartilage, Articular / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D020370:Osteoarthritis, Knee / Q000150:complications / Q000175:diagnosis*
chemical_list: D050071:Bone Density Conservation Agents