title: Dihydrooxazine oxides as key intermediates in organocatalytic Michael additions of aldehydes to nitroalkenes.
abstract: Pause and play: dihydrooxazine oxides are stable intermediates that are protonated directly, without the intermediacy of the zwitterions, in organocatalytic Michael additions of aldehydes and nitroalkenes (see scheme, R=alkyl). Protonation of these species explains both the role of the acid co-catalyst in these reactions, and the observed stereochemistry when the reaction is conducted with α-alkylnitroalkenes.
authors.affiliation: Department of Chemistry, Nanoscience Center, University of Jyväskylä, Finland.
authors.forename: Gokarneswar
authors.initials: G
authors.lastname: Sahoo
authors.forename: Hasibur
authors.initials: H
authors.lastname: Rahaman
authors.forename: Adám
authors.initials: A
authors.lastname: Madarász
authors.forename: Imre
authors.initials: I
authors.lastname: Pápai
authors.forename: Mikko
authors.initials: M
authors.lastname: Melarto
authors.forename: Arto
authors.initials: A
authors.lastname: Valkonen
authors.forename: Petri M
authors.initials: PM
authors.lastname: Pihko