title: Optic disc neovascularization revealing neurosyphilis.
abstract: OBJECTIVE
  To report a case of neurosyphilis revealed by bilateral optic disc neovascularization.
  
  
  METHODS
  Case report.
  
  
  METHODS
  A 39-year-old man presented with a 6-month history of progressive visual loss (20/25 RE, 20/1200 LE) and transient headaches. Fundus examination demonstrated a 1+ vitritis, mild macular edema and large optic disc neovascularization in both eyes. Serological tests for syphilis were positive.
  
  
  RESULTS
  Specific antibiotics and systemic steroids were undertaken and complete regression of disc neovascularization was observed within 6 months.
  
  
  CONCLUSIONS
  Optic disc neovascularization, which is a rare manifestation of chronic uveitis, may lead to the diagnosis of neurosyphilis and be successfully treated by specific antibiotic and steroid therapy.
authors.affiliation: Department of Ophthalmology, CHU-Nancy, France.
authors.forename: F
authors.initials: F
authors.lastname: Trechot
authors.forename: T
authors.initials: T
authors.lastname: Maalouf
authors.forename: P
authors.initials: P
authors.lastname: Kaminsky
authors.forename: K
authors.initials: K
authors.lastname: Angioi
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D009389:Neovascularization, Pathologic / Q000175:diagnosis / Q000209:etiology; D009494:Neurosyphilis / Q000150:complications* / Q000175:diagnosis; D009898:Optic Disk / Q000098:blood supply*; D009901:Optic Nerve Diseases / Q000175:diagnosis* / Q000209:etiology