title: Exocrine pancreatic insufficiency in the cat.
abstract: Exocrine pancreatic insufficiency (EPI) is a syndrome caused by an insufficient amount of pancreatic digestive enzymes in the small intestine. Clinical signs most commonly reported in cats with EPI are weight loss, loose and voluminous stools, steatorrhea, polyphagia, and in some cases a greasy soiling of the hair coat in the perianal region. Serum feline trypsin-like immunoreactivity concentration is the diagnostic test of choice for the diagnosis of affected cats. Treatment of cats with EPI consists of enzyme supplementation with either a powdered pancreatic extract or raw pancreas. Most cats with EPI also have severely decreased serum cobalamin concentrations and may require lifelong parenteral cobalamin supplementation. Most cats respond well to therapy and can have a normal life expectancy and quality of life.
authors.affiliation: Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843-4474, USA. jsteiner@cvm.tamu.edu
authors.forename: Jörg M
authors.initials: JM
authors.lastname: Steiner
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000175:diagnosis* / Q000201:enzymology / Q000628:therapy*; D002415:Cats; D019587:Dietary Supplements; D057487:Enzyme Therapy; D010188:Exocrine Pancreatic Insufficiency / Q000175:diagnosis / Q000201:enzymology / Q000628:therapy / Q000662:veterinary*; D005260:Female; D008297:Male; D011379:Prognosis; D014805:Vitamin B 12 / Q000097:blood; D014806:Vitamin B 12 Deficiency / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary; D015431:Weight Loss
chemical_list: D014805:Vitamin B 12