title: Autophagy-assisted antigen cross-presentation: Autophagosome as the argo of shared tumor-specific antigens and DAMPs.
abstract: It is generally believed that most tumor antigens are passively released from either health or dying tumor cells as intact soluble antigens, peptide fragments complexed with heat shock proteins (HSPs), or packaged in secretary vesicles in the form of microparticles or exosomes. The passive release of tumor antigens is generally non-inflammatory and non-immunogenic; however, results from others and our laboratories suggest that autophagy is critically involved in immunogenic cell death.
authors.affiliation: Cancer Research and Biotherapy Center; Second Affiliated Hospital of Southeast University; Nanjing, China.
authors.forename: Yongxiang
authors.initials: Y
authors.lastname: Yi
authors.forename: Zhenxian
authors.initials: Z
authors.lastname: Zhou
authors.forename: Su
authors.initials: S
authors.lastname: Shu
authors.forename: Yuan
authors.initials: Y
authors.lastname: Fang
authors.forename: Chris
authors.initials: C
authors.lastname: Twitty
authors.forename: Traci L
authors.initials: TL
authors.lastname: Hilton
authors.forename: Sandra
authors.initials: S
authors.lastname: Aung
authors.forename: Walter J
authors.initials: WJ
authors.lastname: Urba
authors.forename: Bernard A
authors.initials: BA
authors.lastname: Fox
authors.forename: Hong-Ming
authors.initials: HM
authors.lastname: Hu
authors.forename: Yuhuan
authors.initials: Y
authors.lastname: Li