title: Redox potential control and applications in microaerobic and anaerobic fermentations.
abstract: Many fermentation products are produced under microaerobic or anaerobic conditions, in which oxygen is undetectable by dissolved oxygen probe, presenting a challenge for process monitoring and control. Extracellular redox potentials that can be detected conveniently affect intracellular redox homeostasis and metabolism, and consequently control profiles of fermentation products, which provide an alternative for monitoring and control of these fermentation processes. This article reviews updated progress in the impact of redox potentials on gene expression, protein biosynthesis and metabolism as well as redox potential control strategies for more efficient production of fermentation products, taking ethanol fermentation by the yeast Saccharomyces under microaerobic conditions and butanol production by the bacterium Clostridium under anaerobic conditions as examples.
authors.affiliation: School of Life Sciences and Biotechnology, Dalian University of Technology, Dalian 116023, China.
authors.forename: Chen-Guang
authors.initials: CG
authors.lastname: Liu
authors.forename: Chuang
authors.initials: C
authors.lastname: Xue
authors.forename: Yen-Han
authors.initials: YH
authors.lastname: Lin
authors.forename: Feng-Wu
authors.initials: FW
authors.lastname: Bai
mesh_terms: D000096:Acetone / Q000378:metabolism; D000693:Anaerobiosis; D000440:Butanols / Q000378:metabolism*; D003013:Clostridium / Q000378:metabolism; D000431:Ethanol / Q000378:metabolism*; D005285:Fermentation / Q000502:physiology*; D015870:Gene Expression; D007218:Industrial Microbiology / Q000379:methods*; D010084:Oxidation-Reduction; D011506:Proteins / Q000378:metabolism; D012440:Saccharomyces / Q000378:metabolism
chemical_list: D000440:Butanols; D011506:Proteins; D000096:Acetone; D000431:Ethanol