title: Vitamin D status in Chinese pregnant women and their newborns in Beijing and their relationships to birth size.
abstract: OBJECTIVE
  To evaluate the prevalence of vitamin D deficiency in pregnant women and their newborns in Beijing, China and the influence of vitamin D deficiency on birth size.
  
  
  METHODS
  A cross-sectional study.
  
  
  METHODS
  Data were collected from pregnant women who delivered during April to May 2010 at 306 Hospital of PLA in Beijing, China.
  
  
  METHODS
  Participants in the study were seventy healthy nulliparous pregnant women with singleton pregnancies who delivered healthy babies at full term and their newborns.
  
  
  RESULTS
  Severe vitamin D deficiency (25-hydroxyvitamin D (25(OH)D) < 25 nmol/l) was detected in 54·5 % of mothers and 46·6 % of newborns. Neither mothers nor newborns had serum 25(OH)D concentrations that reached the normal level (>75 nmol/l). The concentration of 25(OH)D in mothers was positively correlated with that in cord blood (r = 0·89, P < 0·001). Newborns of mothers with severe vitamin D deficiency had lower birth length and birth weight. The head circumference and birth weight were lower in vitamin D-deficient newborns.
  
  
  CONCLUSIONS
  The study indicates that pregnant women and neonates residing in Beijing are at high risk of vitamin D deficiency. Neonatal 25(OH)D concentrations are dependently related to maternal 25(OH)D levels. Maternal and neonatal vitamin D status influences newborn size.
authors.affiliation: Department of Pathology and Experimental Medicine, 306 Hospital of PLA, Chao Yang District, Beijing 100101, PR China.
authors.forename: Shu Jun
authors.initials: SJ
authors.lastname: Song
authors.forename: Shaoyan
authors.initials: S
authors.lastname: Si
authors.forename: Junli
authors.initials: J
authors.lastname: Liu
authors.forename: Xingming
authors.initials: X
authors.lastname: Chen
authors.forename: Ling
authors.initials: L
authors.lastname: Zhou
authors.forename: Guiyue
authors.initials: G
authors.lastname: Jia
authors.forename: Genlan
authors.initials: G
authors.lastname: Liu
authors.forename: Yujing
authors.initials: Y
authors.lastname: Niu
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
authors.forename: Wenying
authors.initials: W
authors.lastname: Zhang
authors.forename: Jianzhong
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000886:Anthropometry; D044466:Asian People; D001724:Birth Weight; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D005312:Fetal Blood / Q000187:drug effects; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D039382:Maternal Nutritional Physiological Phenomena; D009752:Nutritional Status; D011247:Pregnancy; D015995:Prevalence; D014807:Vitamin D / Q000097:blood*; D014808:Vitamin D Deficiency / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D014807:Vitamin D