title: [Efficacy analysis of laparoscopic sleeve gastrectomy in the treatment of obesity-related comorbidities].
abstract: OBJECTIVE
  To investigate the safety and efficacy of laparoscopic sleeve gastrectomy (LSG) for the treatment of obesity and related diseases.
  
  
  METHODS
  Clinical data of 67 patients who underwent LSG between December 2006 and July 2011 were analyzed retrospectively. Improvements in body mass index(BMI), percentage of excess weight loss(EWL), type 2 diabetes mellitus, hypertension and other comorbidities were observed at one year postoperatively.
  
  
  RESULTS
  Laparoscopic procedures were completed in 67 patients without conversion. The operative time was(78±17) min. The postoperative hospital stay was(5.0±1.7) d. The postoperative recovery was uneventful and there were no perioperative death or severe postoperative complication. Sixty-four patients(95.5%) had a postoperative follow up of 1 year. One year after LSG, BMI decreased by(10.4±3.7) kg/m(2) from (37.7±4.1) kg/m(2) preoperatively and EWL was(80.2±27.7)%. In 13 cases of type 2 diabetes mellitus, 7 patients (53.8%, 7/13) were weaned off hypoglycemic agents or insulin. In 11 cases of hypertension, 5 required no medications(45.5%, 5/11). The remission rate was both 100%. There was significant resolution or improvement of other obesity-related comorbidiities, including hyper-triglyceridemia(n=51), hyperuricemia(n=42), sleep apnea syndrome (n=2), osteoarticular disease (n=9), and acanthosis (n=8).
  
  
  CONCLUSIONS
  LSG is safe and feasible for the treatment of obesity and can cure or improve type 2 diabetes mellitus, hypertension and other obesity related comorbidities.
authors.affiliation: Department of General Surgery, The Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, China.
authors.forename: Di-jian
authors.initials: DJ
authors.lastname: Shen
authors.forename: Huan
authors.initials: H
authors.lastname: Ye
authors.forename: Yue-dong
authors.initials: YD
authors.lastname: Wang
authors.forename: Yun
authors.initials: Y
authors.lastname: Ji
authors.forename: Zhi-jie
authors.initials: ZJ
authors.lastname: Xie
authors.forename: Jia
authors.initials: J
authors.lastname: Wu
authors.forename: Xiao-li
authors.initials: XL
authors.lastname: Zhan
authors.forename: Jin-hui
authors.initials: JH
authors.lastname: Zhu
mesh_terms: D000328:Adult; D015897:Comorbidity; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D006973:Hypertension / Q000150:complications; D010535:Laparoscopy / Q000379:methods*; D008297:Male; D009765:Obesity / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome