title: DNA methylation markers for breast cancer prognosis: Unmasking the immune component.
abstract: Currently, most of the prognostic and predictive gene expression signatures emerging for breast cancer concern the tumor component. In Dedeurwaerder et al. we show that DNA methylation profiling of breast tumors is a particularly sensitive means of capturing features of the immune component of breast tumors. Most importantly, correlation is observed between T-cell marker genes and breast cancer clinical outcome.
authors.affiliation: Laboratory of Cancer Epigenetics; Université Libre de Bruxelles; Faculty of Medicine; Brussels, Belgium.
authors.forename: Sarah
authors.initials: S
authors.lastname: Dedeurwaerder
authors.forename: François
authors.initials: F
authors.lastname: Fuks