title: Iron telluride nanorods-based system for the detection of total mercury in blood.
abstract: We have developed a simple, colorimetric iron telluride (FeTe) nanorods (NRs) based system for the detection of mercury, mainly based on the cation exchange reaction between FeTe NRs and Hg(2+). FeTe NRs (length, 105 ± 21 nm) react with Hg(2+) to form HgTe NRs (length, 112 ± 26 nm) and consequently release Fe(2+) ions that catalyzes the oxidation between a peroxidase substrate 2,2'-azino-bis(3-ethylbenzo-thiazoline-6-sulfonic acid) diammonium salt (ABTS) and H(2)O(2). The concentration of Fe(2+) and thereby Hg(2+) can be determined by measuring the absorbance of the ABTS oxidized product at 418 nm. This approach allows the detection of Hg(2+), with a limit of detection of 1.31 nM at a signal-to-noise ratio 3 and a linear range 5-100 nM (R(2)=0.99). The low-cost, simple, sensitive, and reproducible assay has been validated for the detection of Hg(2+) in a blood sample (SRM 955c), with the result being in good agreement with that provided by National Institute of Standards and Technology.
authors.affiliation: Department of Chemistry, National Taiwan University, 1, Section 4, Roosevelt Road, Taipei 106, Taiwan.
authors.forename: Prathik
authors.initials: P
authors.lastname: Roy
authors.forename: Zong-Hong
authors.initials: ZH
authors.lastname: Lin
authors.forename: Chi-Te
authors.initials: CT
authors.lastname: Liang
authors.forename: Huan-Tsung
authors.initials: HT
authors.lastname: Chang
mesh_terms: D052160:Benzothiazoles; D003124:Colorimetry; D006801:Humans; D006861:Hydrogen Peroxide; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D007474:Ion Exchange; D058085:Iron Compounds / Q000737:chemistry*; D013058:Mass Spectrometry; D008628:Mercury / Q000097:blood*; D043942:Nanotubes / Q000737:chemistry*; D059629:Signal-To-Noise Ratio; D013451:Sulfonic Acids; D013691:Tellurium / Q000737:chemistry*; D013696:Temperature
chemical_list: D052160:Benzothiazoles; D007202:Indicators and Reagents; D058085:Iron Compounds; D013451:Sulfonic Acids; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; D006861:Hydrogen Peroxide; D008628:Mercury; D013691:Tellurium