title: Continuous topical oxygen for the treatment of chronic wounds: a pilot study.
abstract: Oxygen is essential for all stages of wound healing. Previous research has shown topical administration of oxygen to have positive effects on wound healing. In this study, the application of transdermal continuous topical oxygen therapy (TCOT) was evaluated for its effect on chronic wound healing in 9 patients. After 4 weeks of treatment, mean wound surface area and wound infection checklist scores were significantly reduced. Signs of bacterial damage were also reduced. Findings from this study suggest TCOT may be beneficial in promoting chronic wound healing.
authors.affiliation: School of Nursing, Queen's University, Kingston, Ontario, Canada.
authors.forename: Kevin Y
authors.initials: KY
authors.lastname: Woo
authors.forename: Patricia M
authors.initials: PM
authors.lastname: Coutts
authors.forename: R Gary
authors.initials: RG
authors.lastname: Sibbald
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D016503:Drug Delivery Systems / Q000295:instrumentation / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000008:administration & dosage*; D010865:Pilot Projects; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects* / Q000502:physiology; D014946:Wound Infection / Q000517:prevention & control*
chemical_list: D010100:Oxygen