title: Passive cooling during transport of asphyxiated term newborns.
abstract: OBJECTIVE
  To evaluate the efficacy and safety of passive cooling during transport of asphyxiated newborns.
  
  
  METHODS
  Retrospective medical record review of newborns with perinatal asphyxia transported for hypothermia between July 2007 and June 2010.
  
  
  RESULTS
  Of 43 newborns transported, 27 were passively cooled without significant adverse events. Twenty (74%) passively cooled newborns arrived with temperature between 32.5 and 34.5 °C. One newborn arrived with a temperature <32.5, and 6 (22%) had temperatures >34.5 °C. Time from birth to hypothermia was significantly shorter among passively cooled newborns compared with newborns not cooled (215 vs 327 min, P<0.01), even though time from birth to admission to Boston Children's Hospital was similar (252 vs 259 min, P=0.77). Time from birth to admission was the only significant predictor of increased time to reach target temperature (P=0.001).
  
  
  CONCLUSIONS
  Exclusive passive cooling achieves significantly earlier initiation of effective hypothermia for asphyxiated newborns but should not delay transport for active cooling.
authors.affiliation: Department of Pediatrics, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA 02115, USA.
authors.forename: D
authors.initials: D
authors.lastname: O'Reilly
authors.forename: M
authors.initials: M
authors.lastname: Labrecque
authors.forename: M
authors.initials: M
authors.lastname: O'Melia
authors.forename: J
authors.initials: J
authors.lastname: Bacic
authors.forename: A
authors.initials: A
authors.lastname: Hansen
authors.forename: J S
authors.initials: JS
authors.lastname: Soul
mesh_terms: D001034:Apgar Score; D001238:Asphyxia Neonatorum / Q000175:diagnosis / Q000628:therapy*; D001724:Birth Weight; D001831:Body Temperature; D004569:Electroencephalography; D005260:Female; D005865:Gestational Age; D006801:Humans; D007036:Hypothermia, Induced / Q000379:methods*; D020925:Hypoxia-Ischemia, Brain / Q000517:prevention & control; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D008297:Male; D009460:Neurologic Examination; D063868:Patient Outcome Assessment; D011379:Prognosis; D012189:Retrospective Studies; D014187:Transportation of Patients