title: Update on gout 2012.
abstract: Significant scientific advances have been made over the last five years in the pathogenesis of hyperuricemia and understanding how monosodium urate (MSU) crystals provoke gout. New detection methods using ultrasound (US) have been evaluated and may become part of our routine diagnostic approach in a patient presenting with gout. This review will concentrate on the latest developments in the field, and discuss how these data may impact on clinical practice. Finally, a brief review of the therapeutic implications and new therapies that have become available will be presented.
authors.affiliation: Service de Rhumatologie, Département de l'Appareil Locomoteur, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. alexanderkai-lik.so@chuv.ch
authors.forename: Alexander
authors.initials: A
authors.lastname: So
authors.forename: Nathalie
authors.initials: N
authors.lastname: Busso
mesh_terms: D019468:Disease Management; D006073:Gout / Q000175:diagnosis* / Q000188:drug therapy* / Q000378:metabolism; D006074:Gout Suppressants / Q000627:therapeutic use*; D006801:Humans; D033461:Hyperuricemia / Q000175:diagnosis / Q000188:drug therapy / Q000378:metabolism; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D014527:Uric Acid / Q000378:metabolism
chemical_list: D006074:Gout Suppressants; D014527:Uric Acid