title: Use of a deslorelin implant for influencing sex hormones and male behaviour in a stallion - Case report.
abstract: This case report describes the use of a subcutaneously applied 4.7-mg deslorelin acetate implant in a three-year-old Arabian crossbred stallion showing unwanted strong male behaviour. Following deslorelin acetate implantation the stallion showed a short transitional increase in male behaviour. A 'gelding-like' behaviour was noted 15 days (D15) after treatment. The horse was surgically castrated at the owners request at D52 after treatment. Serum testosterone, oestradiol-17β and oestrone sulphate values decreased after deslorelin acetate implantation, but serum LH and FSH levels remained unchanged. Histopathological analysis of both testes and sperm analysis revealed a reduced spermatogenesis at D52. The testicular volume decreased after treatment. The use of a subcutaneously applied deslorelin acetate implant might be a promising tool to change the behaviour of aggressive stallions.
authors.affiliation: Freie Universität Berlin Equine Clinic: Surgery and Radiology, Department of Veterinary Medicine Oertzenweg 19b 14163 Berlin Germany.
authors.forename: Susanne
authors.initials: S
authors.lastname: Schönert
authors.forename: Martina
authors.initials: M
authors.lastname: Reher
authors.forename: Achim D
authors.initials: AD
authors.lastname: Gruber
authors.forename: Bianca
authors.initials: B
authors.lastname: Carstanjen
mesh_terms: D000818:Animals; D012739:Gonadal Steroid Hormones; D007987:Gonadotropin-Releasing Hormone; D006736:Horses; D007986:Luteinizing Hormone; D008297:Male; D013737:Testis; D013739:Testosterone
chemical_list: D012739:Gonadal Steroid Hormones; D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D007986:Luteinizing Hormone