title: Radiation-induced anaplastic ependymoma with a remarkable clinical response to temozolomide: a case report.
abstract: Radiation-induced gliomas are uncommon and therapeutic options are limited due to prior exposure to radiotherapy. Meanwhile, the chemotherapeutic response of anaplastic ependymoma, another rare entity in adults, is often disappointing. We report on the first recorded case of radiation-induced anaplastic ependymoma, in which an excellent clinical response to temozolomide was demonstrated.
authors.affiliation: Department of Neurosurgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: H M
authors.initials: HM
authors.lastname: Khoo
authors.forename: H
authors.initials: H
authors.lastname: Kishima
authors.forename: M
authors.initials: M
authors.lastname: Kinoshita
authors.forename: Y
authors.initials: Y
authors.lastname: Goto
authors.forename: N
authors.initials: N
authors.lastname: Kagawa
authors.forename: N
authors.initials: N
authors.lastname: Hashimoto
authors.forename: M
authors.initials: M
authors.lastname: Maruno
authors.forename: T
authors.initials: T
authors.lastname: Yoshimine
mesh_terms: D000328:Adult; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use*; D001254:Astrocytoma / Q000532:radiotherapy / Q000601:surgery; D002528:Cerebellar Neoplasms / Q000532:radiotherapy / Q000601:surgery; D003606:Dacarbazine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004806:Ependymoma / Q000188:drug therapy*; D005260:Female; D006801:Humans; D009381:Neoplasms, Radiation-Induced / Q000188:drug therapy*; D016609:Neoplasms, Second Primary / Q000188:drug therapy*; D000077204:Temozolomide
chemical_list: D018906:Antineoplastic Agents, Alkylating; D003606:Dacarbazine; D000077204:Temozolomide