title: [Dysthimia or chronic depression: what do we know about its pharmacological treatment?].
abstract: The term dysthymia is applied to a clinical picture characterized by depressive feelings of low intensity and chronic evolution. Psychiatric nosology includes it among the mood disorders or among neurosis and personality disorders. This ambiguity has empirical consequences, since bibliography examining the efficacy of the different treatments is relatively scarce, in particular if we consider the incidence of the dysthymic disorder, that rounds 3% of general population. In this work the history of the nosology of dysthimia, the efficacy of pharmacological approaches and a brief mention about the efficacy of adding psychotherapy are summarized. Current literature indicates that antidepressants, independently of the group they form part of, are better than placebo, that maintenance treatment should be recommended and that psychotherapy could bring an additional benefit.
authors.affiliation: Instituto de Investigaciones Farmacológicas, CONICET-UBA. swikinsk@ffyb.uba.ar
authors.forename: Silvia
authors.initials: S
authors.lastname: Wikinski
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use*; D002908:Chronic Disease; D003866:Depressive Disorder / Q000188:drug therapy; D019263:Dysthymic Disorder / Q000188:drug therapy*; D006801:Humans
chemical_list: D000928:Antidepressive Agents