title: Spatial control of plasma membrane domains: ROP GTPase-based symmetry breaking.
abstract: Breaking of the cell membrane symmetry to form polarized or localized domains/regions of the plasma membrane (PM) is a fundamental cellular process that occurs in essentially all cellular organisms, and is required for a wide variety of cellular functions/behaviors including cell morphogenesis, cell division and cell differentiation. In plants, the development of localized or polarized PM domains has been linked to a vast array of cellular and developmental processes such as polar cell expansion, asymmetric cell division, cell morphogenesis, the polarization of auxin transporters (and thus auxin polar transport), secondary cell wall patterning, cell type specification, and tissue pattern formation. Rho GTPases from plants (ROPs) are known to be involved in many of these processes. Here, we review the current knowledge on ROP involvement in breaking symmetry and propose that ROP-based self-organizing signaling may provide a common mechanism for the spatial control of PM domains required in various cellular and developmental processes in plants.
authors.affiliation: Center for Plant Cell Biology and Department of Botany and Plant Sciences, University of California, Riverside, CA 92521, USA. yang@ucr.edu
authors.forename: Zhenbiao
authors.initials: Z
authors.lastname: Yang
authors.forename: Irene
authors.initials: I
authors.lastname: Lavagi
mesh_terms: D017360:Arabidopsis / Q000201:enzymology / Q000502:physiology; D029681:Arabidopsis Proteins / Q000378:metabolism; D060049:Asymmetric Cell Division; D002462:Cell Membrane / Q000201:enzymology* / Q000502:physiology; D016764:Cell Polarity; D048430:Cell Shape; D002473:Cell Wall / Q000502:physiology; D025461:Feedback, Physiological; D019204:GTP-Binding Proteins / Q000378:metabolism; D007210:Indoleacetic Acids / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D008870:Microtubules / Q000378:metabolism; D059828:Plant Cells / Q000201:enzymology; D017434:Protein Structure, Tertiary; D020741:rho GTP-Binding Proteins / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; D007210:Indoleacetic Acids; D008565:Membrane Proteins; D019204:GTP-Binding Proteins; C501663:ROP1 protein, Arabidopsis; D020741:rho GTP-Binding Proteins