title: Ganglioneuroblastoma in a young child with Turner syndrome.
abstract: X chromosome aneuploidy has been identified as a potential risk factor for the development of neuroblastic tumors. We report a case of a 4-year-old girl with a 45,X karyotype incidentally discovered to have a large ganglioneuroblastoma on initial screening ultrasound. The incidence of these tumors in girls with Turner syndrome as well as their possible relationship to recombinant human growth hormone treatment is discussed.
authors.affiliation: Division of Pediatric Endocrinology, Department of Pediatrics, Tripler Army Medical Center, Mail Code MCHK-PE, 1 Jarrett White Road, Honolulu, HI 96859-5000, USA. jordan.pinsker@us.army.mil
authors.forename: Jordan E
authors.initials: JE
authors.lastname: Pinsker
authors.forename: David F
authors.initials: DF
authors.lastname: Crudo
mesh_terms: D000367:Age Factors; D002675:Child, Preschool; D005260:Female; D018305:Ganglioneuroblastoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D010386:Pelvic Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D011859:Radiography; D014424:Turner Syndrome / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery