title: A common diaryl ether intermediate for the gram-scale synthesis of oxazine and xanthene fluorophores.
abstract: Common ground: copper-catalyzed coupling reactions can be used for the high-yielding preparation of widely used oxazine and xanthene fluorophores from a common diaryl ether intermediate on a gram-scale. This general approach may facilitate the future development of novel fluorophores and probes with unique properties.
authors.affiliation: Department of Chemistry, Columbia University, New York, NY 10027, USA.
authors.forename: Andrew V
authors.initials: AV
authors.lastname: Anzalone
authors.forename: Tracy Y
authors.initials: TY
authors.lastname: Wang
authors.forename: Zhixing
authors.initials: Z
authors.lastname: Chen
authors.forename: Virginia W
authors.initials: VW
authors.lastname: Cornish
mesh_terms: D003500:Cyclization; D004986:Ether / Q000737:chemistry; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D010078:Oxazines / Q000138:chemical synthesis* / Q000737:chemistry; D014966:Xanthenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D010078:Oxazines; D014966:Xanthenes; D004986:Ether