title: [Pilonidal disease is a benign condition].
abstract: Malignant transformation in pilonidal disease is rare and never reported in Denmark. There are 75 cases in the literature, mostly squamous cell carcinoma. The cost-benefit of routine histological examination of specimens from pilonidal surgery is questionable, as malignancy is extremely rare. Due to increased incidence of cancer, specimens from patients with many years of pilonidal disease, known immunodeficiencies and/or human papillomavirus infection or clinical abnormal presentation, should always be investigated.
authors.affiliation: Kirurgisk Afdeling, Køge Sygehus, Lykkebækvej 1, Køge. hellegadl@hotmail.com
authors.forename: Helle Gad
authors.initials: HG
authors.lastname: Midtgaard
authors.forename: Susanne
authors.initials: S
authors.lastname: Eiholm
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000175:diagnosis; D010864:Pilonidal Sinus / Q000150:complications / Q000191:economics / Q000473:pathology / Q000601:surgery; D012008:Recurrence; D012445:Sacrococcygeal Region / Q000473:pathology; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology; D013997:Time Factors