title: [A case of acute lymphoblastic leukemia presenting with protein-losing enteropathy].
abstract: Protein-losing enteropathy (PLE) is a syndrome characterized by excessive gastrointestinal protein loss, resulting in hypoproteinemia and edema. A variety of benign and malignant conditions can be associated with PLE and acute leukemia is a very rare cause of PLE. We report a case of PLE associated with acute lymphoblastic leukemia. A 27-year-old man was admitted due to watery diarrhea, epigastric pain and bilateral leg edema. Laboratory findings showed hypoproteinemia and polycythemia. The diagnosis of PLE and acute lymphoblastic leukemia were confirmed on the measurement of fecal a1-antitrypsin clearance and bone marrow examination. After systemic chemotherapy and autologous stem cell transplantation, his clinical symptoms and abnormal laboratory findings were gradually improved.
authors.affiliation: Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.
authors.forename: Seon Young
authors.initials: SY
authors.lastname: Kim
authors.forename: Joong Goo
authors.initials: JG
authors.lastname: Kwon
authors.forename: Myung Hwan
authors.initials: MH
authors.lastname: Kim
authors.forename: Jae Young
authors.initials: JY
authors.lastname: Oh
authors.forename: Jin Hong
authors.initials: JH
authors.lastname: Park
authors.forename: Kyung Chan
authors.initials: KC
authors.lastname: Park
authors.forename: Jung Il
authors.initials: JI
authors.lastname: Ryoo
authors.forename: Hun Mo
authors.initials: HM
authors.lastname: Ryoo
mesh_terms: D000328:Adult; D001854:Bone Marrow Cells / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D011504:Protein-Losing Enteropathies / Q000150:complications / Q000175:diagnosis*; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014178:Translocation, Genetic; D000515:alpha 1-Antitrypsin / Q000032:analysis
chemical_list: D000515:alpha 1-Antitrypsin