title: Rapid detection of Campylobacter antigen by enzyme immunoassay leads to increased positivity rates.
abstract: Campylobacter antigen detection by enzyme immunoassay (EIA) provides rapid results compared to traditional culture. However, concern exists regarding specificity. Verification studies of an EIA compared to culture revealed a positive predictive value (PPV) of 91%, whereas PPV fell to 42% during routine diagnostic testing. We suggest all positive EIA results be confirmed via culture.
authors.affiliation: David Geffen School of Medicine, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, California, USA.
authors.forename: Carmen L
authors.initials: CL
authors.lastname: Giltner
authors.forename: Sandra
authors.initials: S
authors.lastname: Saeki
authors.forename: April M
authors.initials: AM
authors.lastname: Bobenchik
authors.forename: Romney M
authors.initials: RM
authors.lastname: Humphries
mesh_terms: D000942:Antigens, Bacterial / Q000276:immunology*; D002167:Campylobacter / Q000276:immunology* / Q000302:isolation & purification; D002169:Campylobacter Infections / Q000175:diagnosis*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000379:methods; D012680:Sensitivity and Specificity
chemical_list: D000942:Antigens, Bacterial