title: Eccrine squamous syringometaplasia secondary to cutaneous extravasation of docetaxel: report of three cases.
abstract: Eccrine squamous syringometaplasia is characterized by the metaplasia of cuboidal epithelial cells of the eccrine sweat ducts into squamous epithelial cells. It has been associated with several conditions including chemotherapy-related bilateral dermatitis, an entity that can take place in body areas rich in eccrine glands, as well as in acral erythema related to chemotherapy. Only a few cases because of cutaneous extravasation of chemotherapy have been previously reported. We report three cases of eccrine squamous syringometaplasia secondary to extravasation of docetaxel.
authors.affiliation: Department of Dermatology, Hospital Universitario de La Princesa, Madrid, Spain. egallo@aedv.es
authors.forename: Elena
authors.initials: E
authors.lastname: Gallo
authors.forename: Mar
authors.initials: M
authors.lastname: Llamas-Velasco
authors.forename: Raquel
authors.initials: R
authors.lastname: Navarro
authors.forename: Javier
authors.initials: J
authors.lastname: Fraga
authors.forename: Amaro
authors.initials: A
authors.lastname: García-Diez
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects; D000077143:Docetaxel; D003875:Drug Eruptions / Q000150:complications / Q000378:metabolism / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D012867:Skin / Q000378:metabolism / Q000473:pathology; D013543:Sweat Gland Diseases / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D043823:Taxoids / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D000970:Antineoplastic Agents; D043823:Taxoids; D000077143:Docetaxel