title: Symptomatic nonfunctioning parathyroid cysts: role of simple aspiration and ethanol ablation.
abstract: OBJECTIVE
  To evaluate the outcomes of simple aspiration and ethanol ablation in the management of symptomatic nonfunctioning parathyroid cyst (PC).
  
  
  METHODS
  We performed simple aspirations for 12 PCs in 12 patients from March 1997 to June 2010. PC was diagnosed if the aspirated fluid was clear colorless and showed an elevated parathyroid hormone (PTH) level. Ethanol ablation (EA) was performed for recurrent PCs. Simple aspirations were performed using 23-gauge needles and EAs using 18-gauge needles with 99% ethanol under ultrasound (US) guidance. We evaluated cyst volume, cosmetic score, symptom score, and complications.
  
  
  RESULTS
  Mean follow-up period of all patients was 19.2 ± 12.9 months (median, 15.0 months; range, 7-40 months). Simple aspiration was successful in four patients, and the mean volume reduction after simple aspiration was 98.2 ± 3.5% (range, 92.9-100%). In eight recurrent cases, EA resulted in a significant decrease in volume (P=0.012), as well as in cosmetic (P=0.011) and symptom (P=0.01) scores at last follow-up; however two cases of primary failure of EA was treated by repeat EA. No major complications occurred in any patient.
  
  
  CONCLUSIONS
  For symptomatic nonfunctioning PCs, simple aspiration could be a first line procedure for diagnosis and treatment, while EA can be a subsequent treatment modality for recurrent cases.
authors.affiliation: Department of Radiology, Thyroid Center, Daerim St. Mary's Hospital, #978-13 Daerim-dong, Seoul 150-070, Republic of Korea.
authors.forename: Jin Yong
authors.initials: JY
authors.lastname: Sung
authors.forename: Jung Hwan
authors.initials: JH
authors.lastname: Baek
authors.forename: Kyu Sun
authors.initials: KS
authors.lastname: Kim
authors.forename: Ducky
authors.initials: D
authors.lastname: Lee
authors.forename: Eun Ju
authors.initials: EJ
authors.lastname: Ha
authors.forename: Jeong Hyun
authors.initials: JH
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D003560:Cysts / Q000000981:diagnostic imaging / Q000628:therapy*; D000431:Ethanol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010279:Parathyroid Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D012008:Recurrence; D012189:Retrospective Studies; D012597:Sclerosing Solutions / Q000627:therapeutic use; D015911:Sclerotherapy / Q000379:methods*; D013396:Suction / Q000379:methods*; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional / Q000379:methods
chemical_list: D012597:Sclerosing Solutions; D000431:Ethanol