title: Zebrafish genetics gets the Scube on Hedgehog secretion.
abstract: Inspired by a zebrafish mutation, two recent studies by Creanga and colleagues (pp. 1312-1325) and Tukachinsky and colleagues have shed new light on the way in which lipidated Hedgehog proteins are secreted and released from expressing cells, suggesting a model for the sequential action of the Disp and Scube2 proteins in this process.
authors.affiliation: Institute of Molecular and Cell Biology (IMCB), Singapore, Singapore.
authors.forename: Philip W
authors.initials: PW
authors.lastname: Ingham