title: Urinary bisphenol A concentrations in pregnant women.
abstract: Bisphenol A is a chemical that is present in a number of products and types of food packaging. Prenatal exposure to bisphenol A may cause behavioural changes in young children. The aim of this study was to investigate exposure to bisphenol A in pregnant Australian women as a surrogate of neonatal exposure. First morning void urine samples were collected from 26 pregnant women at around week 38 of gestation. Bisphenol A was detectable in 85% of the samples analysed. The median concentration in this group of women was 2.41μg/L with a range of <LOD - 5.66μg/L. Women experiencing their first pregnancy had slightly higher urinary bisphenol A concentrations, as did women with a pre-pregnancy BMI of <25, however these relationships did not reach significance. This study provides the first information on bisphenol A exposure in Australia and reveals that pregnant women have measured biological concentrations of urinary bisphenol A similar to those reported for pregnant women in other developed countries. Given the potential impacts of prenatal bisphenol A exposure, further research in this area is warranted.
authors.affiliation: Centre for Ecosystem Management, Edith Cowan University, 270 Joondalup Drive, Joondalup, WA 6027, Australia. Electronic address: a.callan@ecu.edu.au.
authors.forename: Anna Carita
authors.initials: AC
authors.lastname: Callan
authors.forename: Andrea Lee
authors.initials: AL
authors.lastname: Hinwood
authors.forename: Amy
authors.initials: A
authors.lastname: Heffernan
authors.forename: Geoff
authors.initials: G
authors.lastname: Eaglesham
authors.forename: Jochen
authors.initials: J
authors.lastname: Mueller
authors.forename: Jon Øyvind
authors.initials: JØ
authors.lastname: Odland
mesh_terms: D000328:Adult; D001315:Australia; D001559:Benzhydryl Compounds / Q000009:adverse effects / Q000652:urine*; D004785:Environmental Pollutants / Q000652:urine*; D005260:Female; D005865:Gestational Age; D006801:Humans; D018811:Maternal Exposure / Q000009:adverse effects; D010636:Phenols / Q000009:adverse effects / Q000652:urine*; D011247:Pregnancy; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D004785:Environmental Pollutants; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds