title: Retroviral danger from within: TLR7 is in control.
abstract: In this issue of Immunity, Yu et al. (2012) outline a fascinating model in which TLR7-mediated antibody production acts as a dominant immunosurveillance mechanism against endogenous retroviruses (ERVs), with additional support of TLR3 and TLR9 that function to prevent ERV-mediated malignancy.
authors.affiliation: Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital, University of Bonn, Bonn, Germany.
authors.forename: Arun K
authors.initials: AK
authors.lastname: Mankan
authors.forename: Veit
authors.initials: V
authors.lastname: Hornung