title: Whole grain, dietary fiber, and incidence of endometrial cancer in a Danish cohort study.
abstract: Whole grains and dietary fiber might be inversely associated with endometrial cancer risk through their effects on sex hormone metabolism and body fat. We investigated whether a higher intake of whole grains and dietary fiber was associated with a lower incidence of endometrial cancer in the Diet, Cancer and Health cohort of 29,875 women aged 50-64 years at enrollment in 1993-1997. Information on diet and lifestyle was derived from self-administered questionnaires. The incidence rate ratios and 95% confidence intervals were estimated based on a Cox proportional hazards model. Of the 24,418 women included as cohort members, 217 had a diagnosis of endometrial cancer. No clear associations were found between intake of whole grains or dietary fiber and the incidence of endometrial cancer.
authors.affiliation: Danish Cancer Society Research Center, Copenhagen, Denmark.
authors.forename: Julie
authors.initials: J
authors.lastname: Aarestrup
authors.forename: Cecilie
authors.initials: C
authors.lastname: Kyrø
authors.forename: Jane
authors.initials: J
authors.lastname: Christensen
authors.forename: Mette
authors.initials: M
authors.lastname: Kristensen
authors.forename: Anne Mette Lund
authors.initials: AM
authors.lastname: Würtz
authors.forename: Nina Føns
authors.initials: NF
authors.lastname: Johnsen
authors.forename: Kim
authors.initials: K
authors.lastname: Overvad
authors.forename: Anne
authors.initials: A
authors.lastname: Tjønneland
authors.forename: Anja
authors.initials: A
authors.lastname: Olsen
mesh_terms: D000273:Adipose Tissue; D015992:Body Mass Index; D001939:Bread; D015331:Cohort Studies; D003718:Denmark / Q000453:epidemiology; D004032:Diet; D004043:Dietary Fiber / Q000008:administration & dosage*; D002523:Edible Grain; D016889:Endometrial Neoplasms / Q000453:epidemiology*; D015914:Estrogen Replacement Therapy; D005260:Female; D012739:Gonadal Steroid Hormones / Q000378:metabolism; D006801:Humans; D008019:Life Style; D008593:Menopause; D008875:Middle Aged; D011446:Prospective Studies; D012434:Secale; D011795:Surveys and Questionnaires
chemical_list: D004043:Dietary Fiber; D012739:Gonadal Steroid Hormones