title: Inferior early posttransplant outcomes for recipients of right versus left deceased donor kidneys: an ANZDATA registry analysis.
abstract: Anatomical differences between right and left kidneys could influence transplant outcome. We compared graft function and survival for left and right kidney recipients transplanted from the same deceased organ donor. Adult recipients of 4900 single kidneys procured from 2450 heart beating deceased donors in Australia and New Zealand from 1995 to 2009 were included in a paired analysis. Right kidneys were associated with more delayed graft function (DGF) (25 vs. 21% for left kidneys, p < 0.001) and, if not affected by DGF, a slower fall in serum creatinine. One-year graft survival was lower for right kidneys (89.1 vs. 91.1% for left kidneys, p = 0.001), primarily attributed to surgical complications (66 versus 35 failures for left kidneys). Beyond the first posttransplant year, kidney side was not associated with eGFR, graft or patient survival. Receipt of a right kidney is a risk factor for inferior outcomes in the first year after transplantation. A higher incidence of surgical complications suggests the shorter right renal vein may be contributory. The higher susceptibility of right kidneys to injury should be considered in organ allocation.
authors.affiliation: AP-HM, Hôpital de la Conception, Centre de Néphrologie et Transplantation Rénale, Marseille, France.
authors.forename: H
authors.initials: H
authors.lastname: Vacher-Coponat
authors.forename: S
authors.initials: S
authors.lastname: McDonald
authors.forename: P
authors.initials: P
authors.lastname: Clayton
authors.forename: A
authors.initials: A
authors.lastname: Loundou
authors.forename: R D M
authors.initials: RD
authors.lastname: Allen
authors.forename: S J
authors.initials: SJ
authors.lastname: Chadban
mesh_terms: D000328:Adult; D001926:Brain Death; D005260:Female; D005919:Glomerular Filtration Rate; D006085:Graft Survival; D006801:Humans; D007668:Kidney / Q000473:pathology / Q000503:physiopathology*; D016030:Kidney Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012042:Registries; D051437:Renal Insufficiency / Q000628:therapy*; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D014019:Tissue Donors; D016896:Treatment Outcome