title: [Corneal manifestations of measles in the unvaccinated adult: two typical cases during an epidemic].
abstract: Measles is a disease due to morbillivirus, which belongs to the paramyxoviridae subfamily. It affects mostly young patients, and evolves through four phases: incubation, invasion, eruption and desquamation. Ophthalmic manifestations may occur during the invasive and eruptive phases. Conjunctivitis is the most common ophthalmologic manifestation and is often asymptomatic. Measles keratitis is the most concerning manifestation, with possible corneal ulcer, bacterial superinfection and corneal perforation. We report two cases of acute keratitis occurring during the eruptive phase of measles in two unvaccinated young adults. The involvement was central and strictly epithelial in both patients. The outcome was favorable with symptomatic treatment.
authors.affiliation: Service d'ophtalmologie, université Paris-Sud, hôpital de Bicêtre, Assistance publique-Hôpitaux de Paris, 78, rue du Général-Leclerc, 94275 Le Kremlin-Bicêtre cedex, France.
authors.forename: M
authors.initials: M
authors.lastname: M'garrech
authors.forename: G
authors.initials: G
authors.lastname: Gendron
authors.forename: I
authors.initials: I
authors.lastname: de Monchy
authors.forename: N
authors.initials: N
authors.lastname: Pogorzalek
authors.forename: S
authors.initials: S
authors.lastname: Rebaudet
authors.forename: D
authors.initials: D
authors.lastname: Vittecoq
authors.forename: M
authors.initials: M
authors.lastname: Labetoulle
mesh_terms: D000328:Adult; D003231:Conjunctivitis / Q000209:etiology; D003320:Corneal Ulcer / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D004196:Disease Outbreaks; D004359:Drug Therapy, Combination; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008457:Measles / Q000150:complications* / Q000453:epidemiology; D009883:Ophthalmic Solutions / Q000627:therapeutic use; D010879:Piperazines / Q000627:therapeutic use; D014611:Vaccination; D014801:Vitamin A / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D009883:Ophthalmic Solutions; D010879:Piperazines; D014801:Vitamin A; C005253:picloxydine