title: Laugier-Hunziker syndrome: a report of three cases and literature review.
abstract: Laugier-Hunziker syndrome (LHS) is an acquired pigmentary condition affecting lips, oral mucosa and acral area, frequently associated with longitudinal melanonychia. There is neither malignant predisposition nor underlying systemic abnormality associated with LHS. Herein, we present three uncommon cases of LHS with possibly new feature of nail pigmentation, which were diagnosed during the past 2 years. We also review the clinical and histological findings, differential diagnosis, and treatment of the syndrome in published literature.
authors.affiliation: Department of Oral Medicine, Institute and Hospital of Stomatology, Nanjing University Medical School, Nanjing, China. wenmei-wang@hotmail.com
authors.forename: Wen-Mei
authors.initials: WM
authors.lastname: Wang
authors.forename: Xiang
authors.initials: X
authors.lastname: Wang
authors.forename: Ning
authors.initials: N
authors.lastname: Duan
authors.forename: Hong-Liu
authors.initials: HL
authors.lastname: Jiang
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Huang
mesh_terms: D000328:Adult; D005260:Female; D005882:Gingival Diseases / Q000175:diagnosis; D006801:Humans; D017495:Hyperpigmentation / Q000175:diagnosis*; D008047:Lip Diseases / Q000175:diagnosis*; D008297:Male; D008543:Melanins / Q000032:analysis; D008875:Middle Aged; D009059:Mouth Diseases / Q000175:diagnosis*; D009061:Mouth Mucosa / Q000473:pathology*; D009260:Nail Diseases / Q000175:diagnosis*; D013577:Syndrome; D014060:Tongue Diseases / Q000175:diagnosis
chemical_list: D008543:Melanins