title: Tumor-infiltrating B cells: The ignored players in tumor immunology.
abstract: B cells infiltrating into solid tumors are poorly investigated despite their described positive prognostic value. Whether this antitumor potential comes from either the antigen presentation or the antibody production capacity of B cells, or both, is unknown. Our recently published method on tumor-infiltrating B lymphocyte cloning may prove helpful in unraveling the actual relevance of these cells for tumor development and response to therapy.
authors.affiliation: Division of Molecular Oncology and Immunotherapy; Department of General Surgery; University of Rostock; Rostock, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Linnebacher
authors.forename: Claudia
authors.initials: C
authors.lastname: Maletzki