title: Electrodiagnosis of disorders of neuromuscular transmission.
abstract: This article reviews the use of electrodiagnostic testing in disorders of neuromuscular transmission and discusses the differences between various presynaptic and postsynaptic disorders. Attention is paid to quality control issues that influence the sensitivity of repetitive nerve stimulation and single fiber electromyography. Electrodiagnostic testing, when used as an extension of the clinician's history and physical examination, will provide appropriate direction in establishing the diagnosis.
authors.affiliation: Neuromuscular Disorders Section, Department of Neurology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7025, USA. howardj@neurology.unc.edu
authors.forename: James F
authors.initials: JF
authors.lastname: Howard
mesh_terms: D000200:Action Potentials; D004558:Electric Stimulation / Q000379:methods; D004568:Electrodiagnosis; D004576:Electromyography; D006801:Humans; D018482:Muscle, Skeletal / Q000294:innervation; D009157:Myasthenia Gravis / Q000175:diagnosis; D009412:Nerve Fibers / Q000502:physiology; D009431:Neural Conduction; D020511:Neuromuscular Junction Diseases / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy