title: Severe hepatitis associated with an echovirus 18 infection in an immune-compromised adult.
abstract: Enteroviruses are recognized as important pathogens in pediatric patients; however, they are often overlooked as etiologic agents of disease in adults. Here, we report a case of echovirus 18-associated severe systemic infection and acute liver failure in an adult hematopoietic stem cell transplant recipient. Additionally, we illustrate the utility of molecular methods for the detection and typing of enteroviral infections.
authors.affiliation: Department of Pathology, Stanford University School of Medicine, Stanford, California, USA.
authors.forename: Martina I
authors.initials: MI
authors.lastname: Lefterova
authors.forename: Claudia
authors.initials: C
authors.lastname: Rivetta
authors.forename: Tracy I
authors.initials: TI
authors.lastname: George
authors.forename: Benjamin A
authors.initials: BA
authors.lastname: Pinsky
mesh_terms: D000328:Adult; D004457:Echovirus Infections / Q000150:complications / Q000175:diagnosis*; D004770:Enterovirus / Q000302:isolation & purification*; D006525:Hepatitis, Viral, Human / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D016867:Immunocompromised Host; D017114:Liver Failure, Acute / Q000175:diagnosis / Q000209:etiology; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged