title: Metastatic ability: adapting to a tissue site unseen.
abstract: The microenvironment of the primary as well as the metastatic tumor sites can determine the ability for a disseminated tumor to progress. In this issue of Cancer Cell, Calon and colleagues find that systemic TGF-β can facilitate colon cancer metastatic engraftment and expansion.
authors.affiliation: Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. bhowmickn@cshs.org
authors.forename: Neil A
authors.initials: NA
authors.lastname: Bhowmick