title: [One-stage repair of pharyngeal defect using tongue flaps after resection of advanced stage hypopharyngeal neoplasm and laryngeal neoplasm].
abstract: OBJECTIVE
  To study the effectiveness of one-stage repairing pharyngeal defect with the tongue flaps after resection of advanced stage hypopharyngeal neoplasm and laryngeal neoplasm.
  
  
  METHODS
  Between June 2006 and March 2011, 20 patients with hypopharyngeal neoplasm (8 cases) and laryngeal neoplasm (12 cases) with advanced stage were treated. There were 19 males and 1 female, aged 47-78 years (mean, 62.8 years). All neoplasms were squamous cell carcinomas. The disease duration was 1-8.5 months (mean, 3.9 months). According to the standards of International Union Against Cancer (UICC, 1987), 12 cases were in stage III and 8 cases were in stage IV. The size of pharyngeal defect was 5 cm x 2 cm to 4 cm x 4 cm after resection of tumor. Defects were repaired by the whole base of the tongue flaps in 16 cases and by the horizontal base of the tongue flaps in 4 cases. The size of the flaps ranged from 5 cm x 2 cm to 4 cm x 4 cm. Postoperative radiotherapy and chemotherapy were regularly performed.
  
  
  RESULTS
  The 20 tongue flaps were alive. Healing of incision by first intention was achieved in 18 cases and delayed healing in 2 cases because of subcutaneous fluid. The patients were followed up 12-63 months (mean, 36.7 months). The patients had normal feeding ability and tongue function. Of 20 cases, 12 died and 1 of local recurrence was alive with tumor. The 3-year survival rate was 69.2% (9/13).
  
  
  CONCLUSIONS
  One-stage repair of pharyngeal defect with the tongue flaps after resection of hypopharyngeal neoplasm and laryngeal neoplasm can obtain good effectiveness because the tongue flap is easy-to-obtain and easy-to-survive, and has abundant blood supply.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, PR China.
authors.forename: Yuefeng
authors.initials: Y
authors.lastname: Han
authors.forename: Deshang
authors.initials: D
authors.lastname: Chen
authors.forename: Hui
authors.initials: H
authors.lastname: Li
authors.forename: Mingjie
authors.initials: M
authors.lastname: Zhang
authors.forename: Shiyin
authors.initials: S
authors.lastname: Ma
authors.forename: Lanzhu
authors.initials: L
authors.lastname: Zhou
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000601:surgery; D009367:Neoplasm Staging; D010608:Pharyngeal Diseases / Q000209:etiology / Q000601:surgery*; D010614:Pharynx / Q000601:surgery; D019651:Plastic Surgery Procedures / Q000379:methods; D012189:Retrospective Studies; D013524:Surgical Flaps / Q000098:blood supply; D014059:Tongue / Q000098:blood supply / Q000601:surgery*; D016896:Treatment Outcome