title: Urinary functional outcome following radical cystoprostatectomy and ileal neobladder reconstruction in male patients.
abstract: OBJECTIVE
  Orthotopic neobladder reconstruction is the preferred method of urinary diversion after radical cystoprostatectomy. We evaluated urinary functional outcomes in male patients after orthotopic neobladder using a patient questionnaire.
  
  
  METHODS
  Between 2002 and 2009 patients with bladder cancer were enrolled in a clinical trial, randomly assigned to undergo T pouch or Studer pouch diversion after radical cystoprostatectomy. Male patients were mailed a questionnaire 12 or more months after surgery including items on urinary function, intermittent catheterization, number/size/wetness of pads and mucus leakage.
  
  
  RESULTS
  The questionnaire response rate was 68%. Mean followup was 4.5 years (range 1 to 8). Only 22.3% of patients did not use pads. In the daytime 47% of patients used at least 1 pad, 32.2% used small/mini pads and 22.6% used diapers. At night 72% used pads, 14.7% used small/mini pads and 38.9% used diapers. During the day and night 47% said their pads were dry/barely wet. Overall 62.5% of patients reported mucus leakage. Only 9.5% of patients performed clean intermittent self-catheterization, of whom 70.6% started clean intermittent self-catheterization within the first year after surgery. Increasing age and diabetes mellitus were predictors of urinary function (p = 0.005 and 0.03, respectively) but did not affect pad use.
  
  
  CONCLUSIONS
  Ileal orthotopic neobladder offers good functional results but most patients wear at least 1 pad and many require diapers at night. Increasing age and diabetes mellitus predict worse urinary function but are not associated with pad use. Emptying failure is uncommon and occurs early in the postoperative period. Pad size/wetness and mucus leakage should be considered when evaluating urinary incontinence.
authors.affiliation: Institute of Urology, USC/Norris Comprehensive Cancer Center, Los Angeles, California 90089-2211, USA.
authors.forename: Hamed
authors.initials: H
authors.lastname: Ahmadi
authors.forename: Eila C
authors.initials: EC
authors.lastname: Skinner
authors.forename: Vannita
authors.initials: V
authors.lastname: Simma-Chiang
authors.forename: Gus
authors.initials: G
authors.lastname: Miranda
authors.forename: Jie
authors.initials: J
authors.lastname: Cai
authors.forename: David F
authors.initials: DF
authors.lastname: Penson
authors.forename: Siamak
authors.initials: S
authors.lastname: Daneshmand
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015653:Cystectomy / Q000009:adverse effects / Q000379:methods; D006801:Humans; D007082:Ileum / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011468:Prostatectomy / Q000009:adverse effects / Q000379:methods; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000601:surgery; D014547:Urinary Diversion; D014549:Urinary Incontinence / Q000453:epidemiology* / Q000209:etiology; D016476:Urinary Reservoirs, Continent