title: Genetics of structural hair disorders.
abstract: The identification of causative genes carries the promise of new and innovative therapeutic strategies for both inherited and acquired hair disorders. Moreover, the delineation of the relationships between similar phenotypes, resulting from mutations affecting seemingly distinct regulatory pathways, paves the way to improved diagnosis and treatment. Finally, understanding the biological processes governing HF development and maintenance may have implications for more general disease processes in the skin, such as inflammation and cancer.
authors.affiliation: Department of Dermatology, Columbia University, New York, New York, USA.
authors.forename: Sivan
authors.initials: S
authors.lastname: Harel
authors.forename: Angela M
authors.initials: AM
authors.lastname: Christiano
mesh_terms: D006201:Hair Diseases / Q000235:genetics* / Q000473:pathology*; D018859:Hair Follicle / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D007633:Keratins / Q000235:genetics*
chemical_list: D007633:Keratins