title: Common mechanisms of auditory hallucinations-perfusion studies in epilepsy.
abstract: Auditory hallucinations (AH) occur in various neurological and psychiatric disorders. In psychosis, increased neuronal activity in the primary auditory cortex (PAC) contributes to AH. We investigated functional neuroanatomy of epileptic hallucinations by measuring cerebral perfusion in three patients with AH during simple partial status epilepticus. Hyperperfusion in the temporal lobe covering the PAC occurred in all patients. Our perfusion data support the hypothesis of PAC being a constituting element in the genesis of AH independent of their aetiology.
authors.affiliation: Institute for Diagnostic and Interventional Neuroradiology, Inselspital, Bern University Hospital, and University of Bern, Switzerland.
authors.forename: Martinus
authors.initials: M
authors.lastname: Hauf
authors.forename: Roland
authors.initials: R
authors.lastname: Wiest
authors.forename: Kaspar
authors.initials: K
authors.lastname: Schindler
authors.forename: Kay
authors.initials: K
authors.lastname: Jann
authors.forename: Thomas
authors.initials: T
authors.lastname: Dierks
authors.forename: Werner
authors.initials: W
authors.lastname: Strik
authors.forename: Gerhard
authors.initials: G
authors.lastname: Schroth
authors.forename: Daniela
authors.initials: D
authors.lastname: Hubl
mesh_terms: D000328:Adult; D000368:Aged; D001931:Brain Mapping; D002560:Cerebrovascular Circulation; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications*; D005260:Female; D006212:Hallucinations / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D055420:Perfusion Imaging; D012189:Retrospective Studies; D013113:Spin Labels; D013702:Temporal Lobe / Q000503:physiopathology*
chemical_list: D013113:Spin Labels