title: Ulcerative colitis associated with isolated unilateral hypoglossal nerve palsy.
abstract: We herein describe a rare case of ulcerative colitis associated with unilateral hypoglossal nerve palsy. A 64-year-old woman developed severe active ulcerative colitis and was treated with prednisolone. The dose of oral prednisolone was reduced to 7.5 mg/day, following which the patient noticed slight dysphagia and a speech disturbance. She was diagnosed with unilateral hypoglossal nerve palsy, which was thought to be caused by mononeuritis. She was treated with intravenous methylprednisolone at a dose of 500 mg/day, which improved the neuropathy. When the neuropathy occurred, the patient was in a mildly active stage of ulcerative colitis. We concluded that the mononeuritis observed in the present case was likely an extraintestinal manifestation of ulcerative colitis.
authors.affiliation: Department of Internal Medicine II, Shimane University Faculty of Medicine, Japan. kk461223@med.shimane-u.ac.jp
authors.forename: Kousaku
authors.initials: K
authors.lastname: Kawashima
authors.forename: Shunji
authors.initials: S
authors.lastname: Ishihara
authors.forename: Koji
authors.initials: K
authors.lastname: Doi
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Uemura
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Ohno
authors.forename: Kosuke
authors.initials: K
authors.lastname: Fukuda
authors.forename: Koji
authors.initials: K
authors.lastname: Onishi
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Tada
authors.forename: Akihiko
authors.initials: A
authors.lastname: Oka
authors.forename: Ryusaku
authors.initials: R
authors.lastname: Kusunoki
authors.forename: Nobuhiko
authors.initials: N
authors.lastname: Fukuba
authors.forename: Takafumi
authors.initials: T
authors.lastname: Yuki
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Kinoshita
mesh_terms: D003093:Colitis, Ulcerative / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006801:Humans; D020437:Hypoglossal Nerve Diseases / Q000150:complications* / Q000188:drug therapy; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D011239:Prednisolone; D008775:Methylprednisolone