title: Broad-spectrum antimicrobial and biofilm-disrupting hydrogels: stereocomplex-driven supramolecular assemblies.
abstract: Fighting the resistance: biodegradable and injectable/moldable hydrogels with hierarchical nanostructures were made with broad-spectrum antimicrobial activities and biofilm-disruption capability. They demonstrate no cytotoxicity in vitro, and show excellent skin biocompatibility in animals. These hydrogels have great potential for clinical use in prevention and treatment of various multidrug-resistant infections.
authors.affiliation: Institute of Bioengineering and Nanotechnology, The Nanos, Singapore, Singapore.
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Kazuki
authors.initials: K
authors.lastname: Fukushima
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Coady
authors.forename: Amanda C
authors.initials: AC
authors.lastname: Engler
authors.forename: Shaoqiong
authors.initials: S
authors.lastname: Liu
authors.forename: Yuan
authors.initials: Y
authors.lastname: Huang
authors.forename: John S
authors.initials: JS
authors.lastname: Cho
authors.forename: Yi
authors.initials: Y
authors.lastname: Guo
authors.forename: Lloyd S
authors.initials: LS
authors.lastname: Miller
authors.forename: Jeremy P K
authors.initials: JP
authors.lastname: Tan
authors.forename: Pui Lai Rachel
authors.initials: PL
authors.lastname: Ee
authors.forename: Weimin
authors.initials: W
authors.lastname: Fan
authors.forename: Yi Yan
authors.initials: YY
authors.lastname: Yang
authors.forename: James L
authors.initials: JL
authors.lastname: Hedrick
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology*; D018441:Biofilms / Q000187:drug effects*; D020100:Hydrogels / Q000737:chemistry* / Q000494:pharmacology*; D008854:Microscopy, Electron
chemical_list: D000900:Anti-Bacterial Agents; D020100:Hydrogels