title: [Study of prevalence of rare and difficult to cultivate causative agents of inflammatory diseases of respiratory organs].
abstract: OBJECTIVE
  Study the prevalence of Mycoplasma pneumoniae, Chlamydophila pneumoniae, Chlamydophila psittaci, Legionella pneumophila, Moraxella catarrhalis, Cytomegalovirus, Herpes simplex I/II virus (HSV I/II) in individuals of various age groups with varying inflammatory broncho-pulmonary diseases.
  
  
  METHODS
  384 adults and 1001 children with clinically confirmed diagnoses were examined by PCR method: community-acquired pneumonia, acute bronchitis, bronchial asthma, ARD/ARVD, as well as 127 healthy children and 52 healthy adults. Sputum, smears from posterior fornix of pharynx, blood, saliva from children of the first year of life were used as material for the study.
  
  
  RESULTS
  Wide prevalence of M. pneumoniae and C. pneumoniae among adults and M. pneumoniae among children older than 1 year with inflammatory diseases of respiratory organs was established. C. psittaci, L. pneumophila, M. catarrhalis occurred in isolated cases in both adults and children. Active replication of herpes group viruses was detected in patients of all age groups with inflammatory broncho-pulmonary diseases, and in children Cytomegalovirus replication predominated, in adults--HSV I/II.
  
  
  CONCLUSIONS
  High frequency of prevalence of M. pneumoniae and C. pneumoniae in inflammatory diseases of respiratory tract was established, giving evidence of reasonability and necessity of examination of patients with various nosologic forms of diseases for these species of microorganisms with the aim of effective etiotropic therapy.
authors.forename: E V
authors.initials: EV
authors.lastname: Speranskaia
authors.forename: V N
authors.initials: VN
authors.lastname: Mazepa
authors.forename: E I
authors.initials: EI
authors.lastname: Efimov
authors.forename: N F
authors.initials: NF
authors.lastname: Brusnigina
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology / Q000821:virology; D002648:Child; D002675:Child, Preschool; D023501:Chlamydophila / Q000472:pathogenicity / Q000502:physiology; D017714:Community-Acquired Infections / Q000453:epidemiology* / Q000382:microbiology / Q000821:virology; D003587:Cytomegalovirus / Q000472:pathogenicity / Q000502:physiology; D005260:Female; D006801:Humans; D016952:Legionella pneumophila / Q000472:pathogenicity / Q000502:physiology; D008297:Male; D008875:Middle Aged; D001936:Moraxella catarrhalis / Q000472:pathogenicity / Q000502:physiology; D009177:Mycoplasma pneumoniae / Q000472:pathogenicity / Q000502:physiology; D015995:Prevalence; D035583:Rare Diseases / Q000453:epidemiology* / Q000382:microbiology / Q000821:virology; D012137:Respiratory System / Q000382:microbiology* / Q000821:virology; D012140:Respiratory Tract Diseases / Q000453:epidemiology* / Q000382:microbiology / Q000821:virology; D012426:Russia / Q000453:epidemiology; D018139:Simplexvirus / Q000472:pathogenicity / Q000502:physiology; D014777:Virus Diseases / Q000453:epidemiology* / Q000382:microbiology / Q000821:virology