title: Triple click reaction strategy for macromolecular diversity.
abstract: This Feature Article focuses on the rapidly emerging concept of the "triple click reactions" towards the design and synthesis of macromolecules with well-defined topology and chemical composition, and also precise molecular weight and narrow molecular weight distribution. The term "triple click reaction" used in this feature article is based on the utilization of three chemically and mechanistically different click reactions for polymer-polymer conjugation and post-modification of the polymers. Three sequential click reactions of which two are identical should not be considered to be triple click reactions. The triple click reaction strategy for polymer conjugation and post-modification of polymers is classified in this article based on the resultant architectures: linear and non-linear structures.
authors.affiliation: Department of Chemistry, Istanbul Technical University, Maslak, Istanbul 34469, Turkey. tuncau@itu.edu.tr
authors.forename: Umit
authors.initials: U
authors.lastname: Tunca
mesh_terms: D000480:Alkynes / Q000737:chemistry; D001386:Azides / Q000737:chemistry; D057930:Click Chemistry; D003300:Copper / Q000737:chemistry; D061565:Cycloaddition Reaction; D009589:Nitrogen Oxides / Q000737:chemistry; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry; D014466:Ultraviolet Rays
chemical_list: D000480:Alkynes; D001386:Azides; D009589:Nitrogen Oxides; D011108:Polymers; D013438:Sulfhydryl Compounds; D003300:Copper; C039900:nitroxyl