title: Preparation and in vitro evaluation of plasma-sprayed bioactive akermanite coatings.
abstract: Bioactive ceramic coatings on titanium (Ti) alloys play an important role in orthopedic applications. In this study, akermanite (Ca(2)MgSi(2)O(7)) bioactive coatings are prepared through a plasma spraying technique. The bonding strength between the coatings and Ti-6Al-4V substrates is around 38.7-42.2 MPa, which is higher than that of plasma sprayed hydroxyapatite (HA) coatings reported previously. The prepared akermanite coatings reveal a distinct apatite-mineralization ability in simulated body fluid. Furthermore, akermanite coatings support the attachment and proliferation of rabbit bone marrow mesenchymal stem cells (BMSCs). The proliferation rate of BMSCs on akermanite coatings is obviously higher than that on HA coatings.
authors.affiliation: State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Dingxi Road, Shanghai, 200050, People's Republic of China.
authors.forename: Deliang
authors.initials: D
authors.lastname: Yi
authors.forename: Chengtie
authors.initials: C
authors.lastname: Wu
authors.forename: Xubing
authors.initials: X
authors.lastname: Ma
authors.forename: Heng
authors.initials: H
authors.lastname: Ji
authors.forename: Xuebin
authors.initials: X
authors.lastname: Zheng
authors.forename: Jiang
authors.initials: J
authors.lastname: Chang
mesh_terms: D000818:Animals; D001031:Apatites / Q000737:chemistry; D001854:Bone Marrow Cells / Q000166:cytology; D002448:Cell Adhesion; D049109:Cell Proliferation; D002516:Ceramics / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry; D066298:In Vitro Techniques; D007477:Ions; D008422:Materials Testing / Q000379:methods; D059630:Mesenchymal Stem Cells / Q000166:cytology; D008855:Microscopy, Electron, Scanning / Q000379:methods; D009985:Orthopedics; D011208:Powders; D011817:Rabbits; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D001031:Apatites; D020099:Coated Materials, Biocompatible; D007477:Ions; D011208:Powders; C023506:Glass ceramics; D017886:Durapatite; D014025:Titanium