title: An unusual cause of death: spontaneous urinary bladder perforation.
abstract: Spontaneous urinary bladder perforation is a rare and life-threatening condition similar to traumatic and iatrogenic perforation. The connection with the underlying bladder damage due to previous radiotherapy, inflammation, malignancy, obstruction, or other causes can be found in almost all cases. The symptoms are often nonspecific, and misdiagnosis is common. Here, we present a case of spontaneous urinary bladder perforation due to bladder necrosis in a diabetic woman. She presented to the emergency department with abdominal pain. Exploratory laparotomy was performed by surgeons and revealed necrosis of the anterior and lateral walls of the urinary bladder. Microscopic examination revealed necrotic changes throughout the bladder wall. Ghost-like cellular outlines were compatible with coagulative necrosis. Clusters of bacteria were also present in some necrobiotic tissues. Malignant cells were not present. It appears probable that the infection was due to local interference with the blood supply (arterial, capillary, or venous) combined with the systemic metabolic upset that led to the bladder condition. In our case, we observed partial necrosis of the bladder rather than distortion of the entire blood supply to the bladder as consequences of the microvascular effects of diabetes. Urinary bladder perforation must be considered in the differential diagnosis of patients presenting with free fluid in the abdomen/peritonitis, decreased urine output, and hematuria, and in whom increased levels of urea/creatinine are detected in serum and/ or peritoneal fluid aspirate.
authors.affiliation: Department of Emergency Medicine, İzmir Atatürk Training and Research Hospital, Izmir, Turkey. dronderlimon@yahoo.com
authors.forename: Onder
authors.initials: O
authors.lastname: Limon
authors.forename: Erden Erol
authors.initials: EE
authors.lastname: Unluer
authors.forename: Fulya Cakalagaoglu
authors.initials: FC
authors.lastname: Unay
authors.forename: Orhan
authors.initials: O
authors.lastname: Oyar
authors.forename: Aslı
authors.initials: A
authors.lastname: Sener
mesh_terms: D004636:Emergency Service, Hospital; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009336:Necrosis; D012422:Rupture, Spontaneous; D001743:Urinary Bladder / Q000473:pathology; D001745:Urinary Bladder Diseases / Q000209:etiology* / Q000473:pathology