title: Trichilone, a new C21 steroid from Trichilia connaroides.
abstract: Phytochemical investigation of the leaves of Trichilia connaroides led to the isolation of a new pregnane, trichilone (1), featuring a 2-methoxycyclopent-2-enone moiety, along with a related known compound, 3beta,4alpha-dihydroxypregnane-16-one (2). The structure of 1 was established on the basis of extensive spectroscopic analysis. Compound 1 showed significant root-growth inhibition activity against Amaranthus. mangostanus with an IC50 value of 23.1 ppm.
authors.affiliation: Natural Medicinal Chemistry Research Centre, College of Science, Northwest A & F University, Yangling 712100, Shaanxi, China
authors.forename: Qiang
authors.initials: Q
authors.lastname: Zhang
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.forename: Hong-Ping
authors.initials: HP
authors.lastname: He
authors.forename: Ying-Tong
authors.initials: YT
authors.lastname: Di
authors.forename: Xiao-Jiang
authors.initials: XJ
authors.lastname: Hao
mesh_terms: D006540:Herbicides / Q000633:toxicity; D009682:Magnetic Resonance Spectroscopy; D029582:Meliaceae / Q000737:chemistry*; D008968:Molecular Conformation; D063245:Plant Development; D018515:Plant Leaves / Q000737:chemistry; D018517:Plant Roots / Q000187:drug effects / Q000254:growth & development; D011278:Pregnanes / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D012639:Seeds / Q000187:drug effects / Q000254:growth & development; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013055:Spectrophotometry, Infrared
chemical_list: D006540:Herbicides; D011278:Pregnanes; C576755:trichilone