title: Multifunctional non-viral delivery systems based on conjugated polymers.
abstract: Multifunctional nanomaterials with simultaneous therapeutic and imaging functions explore new strategies for the treatment of various diseases. Conjugated polymers (CPs) are considered as novel candidates to serve as multifunctional delivery systems due to their high fluorescence quantum yield, good photostability, and low cytotoxicity. Highly sensitive sensing and imaging properties of CPs are well reviewed, while the applications of CPs as delivery systems are rarely covered. This feature article mainly focuses on CP-based multifunctional non-viral delivery systems for drug, protein, gene, and cell delivery. Promising directions for the further development of CP-based delivery systems are also discussed.
authors.affiliation: Beijing National Laboratory for Molecular Science, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China.
authors.forename: Gaomai
authors.initials: G
authors.lastname: Yang
authors.forename: Fengting
authors.initials: F
authors.lastname: Lv
authors.forename: Bing
authors.initials: B
authors.lastname: Wang
authors.forename: Libing
authors.initials: L
authors.lastname: Liu
authors.forename: Qiong
authors.initials: Q
authors.lastname: Yang
authors.forename: Shu
authors.initials: S
authors.lastname: Wang
mesh_terms: D017690:Cell Transplantation / Q000379:methods*; D016503:Drug Delivery Systems / Q000379:methods*; D005453:Fluorescence; D018014:Gene Transfer Techniques; D015394:Molecular Structure; D049329:Nanostructures / Q000737:chemistry* / Q000627:therapeutic use; D000078789:Polyacetylene Polymer; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D011145:Polyvinyls; D053279:Polyynes; D013876:Thiophenes
chemical_list: D000078789:Polyacetylene Polymer; D011108:Polymers; D011145:Polyvinyls; D013876:Thiophenes; C470024:poly(4-phenylenevinylene); C473966:poly(phenylene ethynylene); D053279:Polyynes; C066730:polythiophene; C082361:polydiacetylene