title: Antiphospholipid syndrome presenting with acute digital ischaemia, avascular necrosis of the femoral head and superior mesenteric artery thrombus.
abstract: This case illustrates a rare and unique case of a 73-year-old woman who presents with a rapidly developing digital ischaemia, superior mesenteric artery thrombus with positive-lupus anticoagulant. She then developed avascular necrosis of the femoral head. Discussion of the process of diagnosis and management of antiphospholipid syndrome and catastrophic antiphospholipid syndrome are reported.
authors.affiliation: Department of Vascular Surgery, Aberdeen Royal Infirmary, Aberdeen, UK. c.crome@nhs.net
authors.forename: Christopher Robert
authors.initials: CR
authors.lastname: Crome
authors.forename: Sriram
authors.initials: S
authors.lastname: Rajagopalan
authors.forename: Ganesh
authors.initials: G
authors.lastname: Kuhan
authors.forename: Nicholas
authors.initials: N
authors.lastname: Fluck
mesh_terms: D000368:Aged; D015901:Angiography, Digital Subtraction; D003937:Diagnosis, Differential; D005260:Female; D005271:Femur Head Necrosis / Q000209:etiology*; D005385:Fingers / Q000098:blood supply* / Q000473:pathology; D005500:Follow-Up Studies; D005734:Gangrene; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000209:etiology*; D016682:Lupus Coagulation Inhibitor / Q000097:blood; D017538:Mesenteric Artery, Superior; D008641:Mesenteric Vascular Occlusion / Q000175:diagnosis / Q000209:etiology*; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology*; D014034:Toes / Q000098:blood supply* / Q000473:pathology
chemical_list: D016682:Lupus Coagulation Inhibitor