title: Autoaspiration versus manual aspiration in transbronchial needle aspiration in diagnosis of intrathoracic lymphadenopathy.
abstract: BACKGROUND
  Traditionally, aspiration with high negative pressure is recommended to obtain a specimen in transbronchial needle aspiration (TBNA). Undeniably, however, the assistant experiences difficulty in the generation of the negative pressure and precise control of the syringe while performing the procedure.
  
  
  OBJECTIVE
  To evaluate the effectiveness of the autoaspiration method created by our plunger lock in comparison with the conventional manual aspiration in the diagnosis of intrathoracic lymphadenopathy by TBNA.
  
  
  METHODS
  A prospective study was conducted on all patients referred for diagnostic TBNA of enlarged intrathoracic lymph nodes. Both automatic and manual aspiration techniques were performed after the needle had been completely inserted into the nodes. The diagnostic yield and the numbers of diagnostic cells or benign lymphoid cells obtained by each technique were compared in the same node.
  
  
  RESULTS
  A total of 31 intrathoracic lymph nodes in 24 patients were prospectively studied. Twenty-four nodes (77.4%) were malignancies whereas 7 nodes (22.6%) were benign disease. Adequate lymph node samples were obtained in 30 targets (96.8%), and TBNA revealed definite diagnosis for 25 nodes (80.6%). Both aspiration techniques showed exactly the same diagnostic yield. However, the autoaspiration technique provided significantly more adequate samples than manual aspiration techniques did (P=0.003).
  
  
  CONCLUSIONS
  The autoaspiration method using our plunger lock was superior to the manual method in obtaining the numbers of adequate samples in TBNA procedures.
authors.affiliation: *Division of Pulmonary and Critical Care Medicine, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University †Cytology Unit, Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand ‡Division of Chest Surgery, St Marianna University School of Medicine, Kawasaki, Japan.
authors.forename: Viboon
authors.initials: V
authors.lastname: Boonsarngsuk
authors.forename: Atcharaporn
authors.initials: A
authors.lastname: Pongtippan
authors.forename: Sabaitip
authors.initials: S
authors.lastname: Juthakarn
authors.forename: Wison
authors.initials: W
authors.lastname: Boonsarngsuk
authors.forename: Noriaki
authors.initials: N
authors.lastname: Kurimoto