title: Intracystic gadolinium-enhanced MRI in the evaluation of residual giant-cystic craniopharyngiomas in children: report of four cases.
abstract: Residual giant-cystic craniopharyngiomas are amenable to intracavitary bleomycin treatment. Radiologic identification of potential cyst leaks is of paramount for treatment decisions. This report describes our experience in the use of intracystic Gadolinium (Gd)-enhanced MR imaging to determine potential communications between the tumoral cysts and other intra-axial spaces in 4 pediatric patients with residual giant-cystic craniopharyngiomas in whom intracavitary bleomycin treatment was planned after the injection of .1-.2 mL of gadopentetate dimeglumine (Gd-DTPA). In three cases no leaks were found. In one case, whose previous water-soluble iodinated contrast-enhanced CT cystography was negative for leaks, intracystic Gd-enhanced MR showed intraventricular Gd enhancement. We conclude that MR imaging after intracystic administration of Gd-based contrast paramagnetic agents is useful in the detection of potential leaks in cases of giant residual craniopharyngiomas.
authors.affiliation: Departamento de Radiología, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain.
authors.forename: Alberto
authors.initials: A
authors.lastname: Muñoz
authors.forename: María
authors.initials: M
authors.lastname: Martínez-León
authors.forename: Élida
authors.initials: É
authors.lastname: Vázquez
authors.forename: Sandra
authors.initials: S
authors.lastname: Pérez da Rosa
authors.forename: José
authors.initials: J
authors.lastname: Crespo
mesh_terms: D000293:Adolescent; D020863:Central Nervous System Cysts / Q000473:pathology*; D002675:Child, Preschool; D003287:Contrast Media; D003397:Craniopharyngioma / Q000473:pathology*; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010911:Pituitary Neoplasms / Q000473:pathology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA