title: [Metoclopramide as a risk factor for postprandial hyperglycemia in type 2 diabetes].
abstract: Diabetes mellitus is a pathology that has widely spread througout the world in the past decades. Postprandial hyperglycemia plays an important role in the progress of the disease due to the fact that increases the risk for cardiovascular events. This study's aim was to determine if the use of intravenous metoclopramide in patients with Diabetes Mellitus increases the postprandial glycemia.
  
  
  METHODS
  A cohort of patients hospitalized with type 2 diabetes mellitus. Patients were classified as exposed (metoclopramide 10 mg IV) and not exposed, and glycemia preprandial and postprandial at 30, 60 and 120 minutes was measured.
  
  
  RESULTS
  There were 80 patients in each group, and in both groups the general characteristics were homogeneous. The postprandial glycemia in the exposed group was higher at 30, 60, 90 and 120 minutes, being only statistically significant at 120 minutes postprandial (p = < 0,001).
  
  
  CONCLUSIONS
  In conclusion, the use of intravenous metoclopramide is a risk factor to develop postprandial hyperglycemia in diabetic patients.
authors.affiliation: Departamento de Medicina Interna, Unidad Médica de Alta Especialidad n.o 25, Instituto Mexicano del Seguro Social, IMSS, Monterrey, México. hugocus@hotmail.com
authors.forename: H
authors.initials: H
authors.lastname: Gutiérrez-Hermosillo
authors.forename: E
authors.initials: E
authors.lastname: Díaz de León-González
authors.forename: D
authors.initials: D
authors.lastname: Beltrán Santiago
authors.forename: J
authors.initials: J
authors.lastname: Armando Cedillo-Rodríguez
authors.forename: V
authors.initials: V
authors.lastname: Gutiérrez Hermosillo
authors.forename: H E
authors.initials: HE
authors.lastname: Taméz-Pérez
mesh_terms: D000328:Adult; D000368:Aged; D000932:Antiemetics / Q000009:adverse effects* / Q000627:therapeutic use; D001786:Blood Glucose / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000139:chemically induced*; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000139:chemically induced*; D007275:Injections, Intravenous; D008297:Male; D008787:Metoclopramide / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D019518:Postprandial Period; D012307:Risk Factors
chemical_list: D000932:Antiemetics; D001786:Blood Glucose; D008787:Metoclopramide