title: Isolation and biomimetic synthesis of (±)-guajadial B, a novel meroterpenoid from Psidium guajava.
abstract: (±)-Guajadial B (1), an unusual humulene-based meroterpenoid, was isolated as a racemate from the leaves of Psidium guajava, collected from Vietnam. The structure of this novel secondary metabolite was established on the basis of extensive analysis of NMR spectra and confirmed by biomimetic synthesis in a domino three-component coupling reaction.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Gao
authors.forename: Gang-Qiang
authors.initials: GQ
authors.lastname: Wang
authors.forename: Kun
authors.initials: K
authors.lastname: Wei
authors.forename: Ping
authors.initials: P
authors.lastname: Hai
authors.forename: Fei
authors.initials: F
authors.lastname: Wang
authors.forename: Ji-Kai
authors.initials: JK
authors.lastname: Liu
mesh_terms: D015394:Molecular Structure; D000081222:Monocyclic Sesquiterpenes; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D031647:Psidium / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry; D013237:Stereoisomerism; D013729:Terpenes / Q000138:chemical synthesis* / Q000737:chemistry; D014744:Vietnam
chemical_list: D000081222:Monocyclic Sesquiterpenes; D012717:Sesquiterpenes; D013729:Terpenes; C578326:guajadial B; C042686:humulene