title: A CO2-switchable polymer brush for reversible capture and release of proteins.
abstract: We report on a polymer brush that can be switched between extended (hydrated) and collapsed (dehydrated) chain conformational states just by passing CO(2) and an inert gas like N(2) in solution alternately. This conformational change allows for reversible adsorption and release of a protein. In contrast to adding acids and bases for pH change, using gases as the trigger makes it possible to repeat the switching cycle many times without salt accumulation.
authors.affiliation: Département de chimie, Université de Sherbrooke, Sherbrooke, QC, Canada J1K 2R1.
authors.forename: Surjith
authors.initials: S
authors.lastname: Kumar
authors.forename: Xia
authors.initials: X
authors.lastname: Tong
authors.forename: Yves L
authors.initials: YL
authors.lastname: Dory
authors.forename: Martin
authors.initials: M
authors.lastname: Lepage
authors.forename: Yue
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D000327:Adsorption; D002245:Carbon Dioxide / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008689:Methacrylates / Q000737:chemistry; D009584:Nitrogen / Q000737:chemistry; D009757:Nylons / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*; D058525:Quartz Crystal Microbalance Techniques; D014867:Water / Q000737:chemistry
chemical_list: D008689:Methacrylates; D009757:Nylons; D011108:Polymers; D011506:Proteins; C109846:poly(2-(diethylamino)ethyl methacrylate); D014867:Water; D002245:Carbon Dioxide; D009584:Nitrogen