title: Weight and body fat changes in postpartum depot-medroxyprogesterone acetate users.
abstract: BACKGROUND
  Although postpartum depot-medroxyprogesterone acetate (DMPA) recipients often cite weight gain as the reason for discontinuing DMPA, little is known about body composition changes in postpartum DMPA recipients.
  
  
  METHODS
  Women who used DMPA during the postpartum year were measured on several anthropometric dimensions of body composition and compared with women who elected surgical sterilization with bilateral partial salpingectomy (BPS).
  
  
  RESULTS
  After 1 year, DMPA recipients did not differ from the BPS group in weight or percent body fat changes. Almost half the women using DMPA returned to pregravid weight; nearly half gained weight. Higher pre-pregnancy body mass index was associated with weight gain among DMPA recipients.
  
  
  CONCLUSIONS
  DMPA recipients who were overweight or obese before pregnancy may have greater risk for weight gain in the first year postpartum. However, when counseling women, the risk for DMPA-related weight gain should be balanced against the potential for increased weight from subsequent pregnancies.
authors.affiliation: School of Nursing, Ohio University College of Health Sciences and Professions, Athens, OH 45701-2979, USA. nyirati@ohio.edu
authors.forename: Christina M
authors.initials: CM
authors.lastname: Nyirati
authors.forename: Diane L
authors.initials: DL
authors.lastname: Habash
authors.forename: Lynn E T
authors.initials: LE
authors.lastname: Shaffer
mesh_terms: D050154:Adiposity / Q000187:drug effects*; D000293:Adolescent; D000328:Adult; D001823:Body Composition / Q000187:drug effects; D015992:Body Mass Index; D003271:Contraceptive Agents, Female / Q000008:administration & dosage / Q000009:adverse effects*; D003692:Delayed-Action Preparations; D005260:Female; D006801:Humans; D017258:Medroxyprogesterone Acetate / Q000008:administration & dosage / Q000009:adverse effects*; D009765:Obesity / Q000139:chemically induced / Q000453:epidemiology / Q000473:pathology; D009820:Ohio / Q000453:epidemiology; D050177:Overweight / Q000139:chemically induced / Q000453:epidemiology / Q000473:pathology; D011181:Postnatal Care; D011446:Prospective Studies; D015203:Reproducibility of Results; D012306:Risk; D013246:Sterilization, Tubal / Q000009:adverse effects; D015430:Weight Gain / Q000187:drug effects; D055815:Young Adult
chemical_list: D003271:Contraceptive Agents, Female; D003692:Delayed-Action Preparations; D017258:Medroxyprogesterone Acetate