title: Synthesis of imides by palladium-catalyzed C-H functionalization of aldehydes with secondary amides.
abstract: An efficient palladium-catalyzed C-H functionalization of aldehydes with various N-substituted N-heteroarene-2-carboxamides has been developed for the synthesis of secondary imides. The reaction tolerates various functionalities, such as methoxy, fluoro, chloro, and bromo groups. A tentative radical mechanism for a Pd(II)/Pd(IV) catalytic cycle is proposed.
authors.affiliation: Key Laboratory of Mesoscopic Chemistry of the Ministry of Education, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, PR China.
authors.forename: Yong-Jun
authors.initials: YJ
authors.lastname: Bian
authors.forename: Chao-Yue
authors.initials: CY
authors.lastname: Chen
authors.forename: Zhi-Zhen
authors.initials: ZZ
authors.lastname: Huang
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000577:Amides / Q000737:chemistry*; D002384:Catalysis; D007094:Imides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000447:Aldehydes; D000577:Amides; D007094:Imides; D009942:Organometallic Compounds; D010165:Palladium