title: Oncolytic adenoviruses: A potent form of tumor immunovirotherapy.
abstract: The therapeutic efficacy of oncolytic viruses including adenovirus has been thought to depend mostly on direct viral destruction of tumor cells. However, this view has changed with the discovery that oncolysis can also induce innate and antigen-specific adaptive immunity against the tumor. Here we summarize our findings from cancer patients.
authors.affiliation: Laboratory of Immunovirotherapy; University of Helsinki; Helsinki, Finland ; Cancer Gene Therapy Group, Molecular Cancer Biology Program & Transplantation Laboratory & Haartman Institute; University of Helsinki; Helsinki, Finland.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Cerullo
authors.forename: Markus
authors.initials: M
authors.lastname: Vähä-Koskela
authors.forename: Akseli
authors.initials: A
authors.lastname: Hemminki