title: [The Chinese medicine syndrome features of ulcerative colitis by using fluorescence intensity of auto fluorescence imaging].
abstract: OBJECTIVE
  To study the Chinese medicine (CM) syndrome features of ulcerative colitis (UC) by using fluorescence intensity (the ratio of green to red, G/R ratio) of auto fluorescence imaging, thus providing objective evidences for the CM syndrome typing of UC.
  
  
  METHODS
  Totally 49 patients were recruited. They were typed as Dachang damp-heat syndrome (19 cases), Pi-Wei qi deficiency syndrome (30 cases), and the healthy control group (21 cases) on the bases of mucosal morphology of white light endoscopy (WLE) and the G/R ratio of AFI.
  
  
  RESULTS
  Compared with the healthy control group (1.227 +/- 0.137), the G/R ratio in Dachang damp-heat syndrome (0.915 +/- 0.114) and Pi-Wei qi deficiency syndrome (1.147 +/- 0.137) decreased with statistical difference (P < 0.05, P < 0.01). Of them, it was lower in Dachang damp-heat syndrome group (P < 0.01). The case number was mainly dominated in moderate endoscopic index (EI) (11 cases) and severe EI (5 cases) in Dachang damp-heat syndrome group. The case number was mainly dominated in the remission phase (17 cases) and mild EI (7 cases) in Pi-Wei qi deficiency syndrome group. The G/R ratio of the remission phase was higher than that of the active phase (1.220 vs. 0.963, P < 0.01). There was statistical difference in the G/R ratio of the mild EI (1.044), the moderate EI (0.967), and the severe EI (0.830) (P < 0.01).
  
  
  CONCLUSIONS
  The inflammation degree of Dachang damp-heat syndrome was more severe than that of Pi-Wei qi deficiency syndrome. AFI could better reflect the inflammation degree of UC.
authors.affiliation: Department of Endoscope, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai.
authors.forename: Zhen-hua
authors.initials: ZH
authors.lastname: Yang
authors.forename: Ping
authors.initials: P
authors.lastname: Yin
authors.forename: Ao-shuang
authors.initials: AS
authors.lastname: Huang
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000473:pathology*; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods; D008875:Middle Aged; D061848:Optical Imaging; D016711:Yang Deficiency / Q000175:diagnosis; D016710:Yin Deficiency / Q000175:diagnosis