title: Chemical composition and biological activities of essential oil from Hyptis crenata growing in the Brazilian cerrado.
abstract: Essential oils from species of the genus Hyptis are well-known for their significant biological properties, including antimicrobial and acaricidal activities. The essential oil from the aerial parts of H. crenata was obtained by hydrodistillation; bomeol (17.8%), 1,8-cineol (15.6%) and p-cimene (7.9%) were characterized by GC-MS as its major constituents. The essential oil was evaluated in vitro for its antimicrobial activities against six fungal and five bacterial strains, by measuring the respective MICs, MFCs and MBCs, using broth microdilution methods. The strongest bactericidal activities were shown against Staphylococcus aureus and Enterococcus faecalis, while the strongest fungicidal activities were against Cryptococcus neoformans, Candida glabrata and Candida tropicalis. The oil was also assessed for its anti-tick properties and, at a concentration of 2.5%, it significantly inhibited in vivo oviposition of engorged females of the cattle tick Rhipicephalus (Boophilus) microplus, using the adult immersion test., with an effectiveness of 94.4%.
authors.affiliation: Centro de Cidncias Exatas e Tecnologia, Universidade Federal de Mato Grosso do Sul, Av. Senador Filinto Muller 1555, Campo Grande, MS 79074-460, Brazil.
authors.forename: Ivana Maria Póvoa
authors.initials: IM
authors.lastname: Violante
authors.forename: Walmir Silva
authors.initials: WS
authors.lastname: Garcez
authors.forename: Carolina da Silva
authors.initials: Cda S
authors.lastname: Barbosa
authors.forename: Fernanda Rodrigues
authors.initials: FR
authors.lastname: Garcez
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001938:Brazil; D005260:Female; D005658:Fungi / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D031331:Hyptis / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology* / Q000633:toxicity; D010575:Pesticides / Q000633:toxicity; D048494:Rhipicephalus
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D009822:Oils, Volatile; D010575:Pesticides