title: Hyaluronated fullerenes with photoluminescent and antitumoral activity.
abstract: Hyaluronated fullerene has strong near-infrared (NIR) fluorescence intensity without labelling with any fluorophores or isotopes. This fullerene allowed high-resolution fluorescent imaging of tumor sites in vivo and resulted in a significant regression of HCT-116 tumors.
authors.affiliation: Division of Biotechnology, The Catholic University of Korea, 43-1, Yeokgok 2-dong, Wonmi-gu, Bucheon, Gyeonggi-do 420-743, Republic of Korea.
authors.forename: Dong Sup
authors.initials: DS
authors.lastname: Kwag
authors.forename: Kyeongsoon
authors.initials: K
authors.lastname: Park
authors.forename: Kyung Taek
authors.initials: KT
authors.lastname: Oh
authors.forename: Eun Seong
authors.initials: ES
authors.lastname: Lee
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000737:chemistry* / Q000627:therapeutic use / Q000633:toxicity; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D005456:Fluorescent Dyes / Q000737:chemistry; D037741:Fullerenes / Q000737:chemistry*; D045325:HCT116 Cells; D006801:Humans; D006820:Hyaluronic Acid / Q000737:chemistry*; D007834:Lasers; D051379:Mice; D008819:Mice, Nude; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology; D017319:Photosensitizing Agents / Q000737:chemistry / Q000627:therapeutic use / Q000633:toxicity; D019265:Spectroscopy, Near-Infrared; D014183:Transplantation, Heterologous
chemical_list: D000970:Antineoplastic Agents; D005456:Fluorescent Dyes; D037741:Fullerenes; D017319:Photosensitizing Agents; D006820:Hyaluronic Acid