title: Psoriatic patients have an increased risk of polycystic ovary syndrome: results of a cross-sectional analysis.
abstract: OBJECTIVE
  To define the prevalence and the features of polycystic ovary syndrome (PCOS) in patients with psoriasis. To our knowledge, the association between PCOS and psoriasis has not been explored in previous studies. Psoriasis is linked with metabolic syndrome, insulin resistance, and non-alcoholic fatty liver disease, which are features often associated with PCOS.
  
  
  METHODS
  A cross-sectional analysis was performed between January 2010 and April 2012.
  
  
  METHODS
  Unit of human reproductive pathophysiology, Catholic University Hospital.
  
  
  METHODS
  We prospectively analyzed 51 patients with psoriasis and 102 healthy age- and body mass index (BMI)-matched controls.
  
  
  METHODS
  None.
  
  
  METHODS
  The prevalence and characteristics of PCOS women of reproductive age with chronic plaque psoriasis.
  
  
  RESULTS
  The prevalence of PCOS was greater in patients with psoriasis than in matched control subjects (47.05% and 11.76%, respectively; odds ratio, 6.66; 95% confidence interval 2.95-15.07). Among the women with psoriasis, the prevalence of Psoriasis Area and Severity Index ≥10 was higher in patients with PCOS than in subjects without PCOS (odds ratio, 3.5; 95% confidence interval 1.04-11.72).
  
  
  CONCLUSIONS
  The prevalence of PCOS in women with psoriasis is remarkably greater than in age- and BMI-matched control women.
authors.affiliation: Institute of Obstetrics and Gynaecology, Università Cattolica del Sacro Cuore, Rome, Italy. morofrancy@gmail.com
authors.forename: Francesca
authors.initials: F
authors.lastname: Moro
authors.forename: Clara
authors.initials: C
authors.lastname: De Simone
authors.forename: Andrea
authors.initials: A
authors.lastname: Morciano
authors.forename: Anna
authors.initials: A
authors.lastname: Tropea
authors.forename: Francesca
authors.initials: F
authors.lastname: Sagnella
authors.forename: Carola
authors.initials: C
authors.lastname: Palla
authors.forename: Elisa
authors.initials: E
authors.lastname: Scarinci
authors.forename: Angela
authors.initials: A
authors.lastname: Teti
authors.forename: Giacomo
authors.initials: G
authors.lastname: Caldarola
authors.forename: Magda
authors.initials: M
authors.lastname: D'Agostino
authors.forename: Salvatore
authors.initials: S
authors.lastname: Mancuso
authors.forename: Antonio
authors.initials: A
authors.lastname: Lanzone
authors.forename: Rosanna
authors.initials: R
authors.lastname: Apa
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006706:Homeostasis; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008055:Lipids / Q000097:blood; D016017:Odds Ratio; D011085:Polycystic Ovary Syndrome / Q000453:epidemiology* / Q000473:pathology*; D015995:Prevalence; D011446:Prospective Studies; D011565:Psoriasis / Q000453:epidemiology* / Q000473:pathology*; D012307:Risk Factors; D049629:Waist-Hip Ratio
chemical_list: D008055:Lipids