title: Opposing consequences of signaling through EGF family members: Escape from CTLs could be a bait for NK cells.
abstract: Oncogenes have been traditionally viewed as molecular drivers for tumor growth and survival. Recent evidence indicates that oncogenes may facilitate the escape of malignant cells from immune recognition and elimination. In this article, we discuss the implications of the overexpression of epidermal growth factor receptor (EGFR) family members on immune escape of tumors and immunotherapy.
authors.affiliation: Department of Oncology and Pathology; Immune and Gene Therapy Laboratory; Cancer Center Karolinska; Karolinska Institutet; Stockholm, Sweden.
authors.forename: Rolf
authors.initials: R
authors.lastname: Kiessling
authors.forename: Riki
authors.initials: R
authors.lastname: Okita
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Mougiakakos
authors.forename: Yumeng
authors.initials: Y
authors.lastname: Mao
authors.forename: Dhifaf
authors.initials: D
authors.lastname: Sarhan
authors.forename: Erik
authors.initials: E
authors.lastname: Wennerberg
authors.forename: Barbara
authors.initials: B
authors.lastname: Seliger
authors.forename: Andreas
authors.initials: A
authors.lastname: Lundqvist
authors.forename: Kousaku
authors.initials: K
authors.lastname: Mimura
authors.forename: Koji
authors.initials: K
authors.lastname: Kono