title: Resolution of nebivolol-induced coronary vasospasm by intracoronary nitroglycerin during a coronary angiogram.
abstract: Nebivolol is a novel beta1-selective beta-blocker with vasodilator properties mediated through activation of the l-arginine-nitric oxide pathway. There is no published report of coronary artery spasm associated with nebivolol. We describe a 64-year-old female patient who developed unstable angina secondary to nebivolol-induced vasospastic angina which was also visible during coronary angiography.
authors.affiliation: Louisiana State University Health Sciences Center, Shreveport, USA.
authors.forename: Nuri I
authors.initials: NI
authors.lastname: Akkus
authors.forename: Saurabh
authors.initials: S
authors.lastname: Rajpal
authors.forename: Elvis
authors.initials: E
authors.lastname: Peter
mesh_terms: D058671:Adrenergic beta-1 Receptor Antagonists / Q000009:adverse effects*; D001578:Benzopyrans / Q000009:adverse effects*; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000139:chemically induced* / Q000188:drug therapy*; D004983:Ethanolamines / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D000068577:Nebivolol; D005996:Nitroglycerin / Q000008:administration & dosage*; D014665:Vasodilator Agents / Q000008:administration & dosage*
chemical_list: D058671:Adrenergic beta-1 Receptor Antagonists; D001578:Benzopyrans; D004983:Ethanolamines; D014665:Vasodilator Agents; D000068577:Nebivolol; D005996:Nitroglycerin