title: Thermal ablation for partial splenectomy hemostasis, spleen trauma, splenic metastasis and hypersplenism.
abstract: Many studies have been conducted on splenic thermal ablation for partial splenectomy hemostasis, spleen trauma, splenic metastasis and hypersplenism. In this article, we review the evolution and current status of radiofrequency and microwave ablation in the treatment of spleen diseases. All publications from 1990 to 2011 on radiofrequency and microwave ablation for partial splenectomy hemostasis, spleen trauma, splenic metastasis and hypersplenism were retrieved by searching PubMed. Thermal ablation in the spleen for partial splenectomy hemostasis, spleen trauma, splenic metastasis and hypersplenism can preserve part of the spleen and maintain splenic immunologic function. Thermal ablation for assisting hemostasis in partial splenectomy minimizes blood loss during operation. Thermal ablation for spleen trauma reduces the number of splenectomy and the amount of blood transfusion. Thermal ablation for splenic metastasis is minimally invasive and can be done under the guidance of an ultrasound, which helps shorten the recovery time. Thermal ablation for hypersplenism increases platelet (PLT) and white blood cell (WBC) counts and improves liver function. It also helps to maintain splenic immunologic function and even improves splenic immunologic function in the short-term. In conclusion, thermal ablative approaches are promising for partial splenectomy hemostasis, spleen trauma, splenic metastasis and hypersplenism. In order to improve therapeutic effects, directions for future studies may include standardized therapeutic indications, prolonged observation periods and enlarged sample sizes.
authors.affiliation: Department of Ultrasound, General Hospital of Beijing Military Command, Beijing, China.
authors.forename: Ya-Qi
authors.initials: YQ
authors.lastname: Duan
authors.forename: Ping
authors.initials: P
authors.lastname: Liang
mesh_terms: D016063:Blood Loss, Surgical / Q000517:prevention & control*; D017115:Catheter Ablation / Q000009:adverse effects; D006489:Hemostatic Techniques; D006801:Humans; D006971:Hypersplenism / Q000601:surgery*; D008872:Microwaves / Q000009:adverse effects / Q000627:therapeutic use*; D013154:Spleen / Q000276:immunology / Q000293:injuries / Q000473:pathology / Q000601:surgery*; D013156:Splenectomy / Q000009:adverse effects*; D013160:Splenic Neoplasms / Q000556:secondary / Q000601:surgery*; D016896:Treatment Outcome