title: [Surgical repair of truncus arteriosus in children: early results and long-term outcomes].
abstract: OBJECTIVE
  To recite early results and long-term outcomes after surgical repair of persistent truncus arteriosus (PTA).
  
  
  METHODS
  The clinic data of 54 patients underwent surgical repair for PTA from January 1999 to December 2009 was analyzed retrospectively. There were 36 male and 18 female patients, with a mean age of (9 ± 10) months (range, 1 to 38 months; median, 5 months). Preoperative mechanical ventilation was required in 5 patients. The surgical procedures were closure of ventricular septal defect and re-establishment of continuity between right ventricle and pulmonary artery. The right ventricular outflow tract (RVOT) was reconstructed by direct anastomosis pulmonary artery to right ventriculotomy with anterior wall patch enlargement (28 cases), or by inserting conduits (26 cases). Valvuloplasty were performed in 4 patients with truncal valves moderate to severe insufficiency and aortoplasty in 3 patients with interrupted aortic arch (IAA).
  
  
  RESULTS
  There were 3 patients (5.6%) died of pulmonary hypertensive crisis in hospital. The mean duration of ventilation was 6.8 days in 5 patients who were intubated before operation, while the others were 3.6 days. Forty-seven (92.2%) patients were followed-up for mean (6.8 ± 2.5) years (from 2.5 to 11.0 years). There were 2 patients with mild to moderate aortic regurgitation. One patient with aortic arch obstruction underwent balloon dilatation 2 years postoperatively. Among those patients who underwent direct anastomoses, 8 (32.0%) patients had pulmonary branch stenosis at 7 months to 1.5 years postoperatively, 12 (48.0%) patients were freedom from surgical reintervention 5.0 to 11.0 years postoperatively. Among those inserting conduits, 7 patients (31.8%) had conduit stenosis at 2.8 to 7.0 years after operation. Reoperations were performed for RVOT in 15 patients and there was no mortality.
  
  
  CONCLUSIONS
  It is difficult to treat the PTA patients with IAA, intra-mural coronary artery or mechanical ventilation support before operation. The technique of direct anastomosis between pulmonary artery and right ventricle offers the potential growth for RVOT, but bilateral pulmonary branch stenosis may be occurred at earlier period of postoperation in some patients.
authors.affiliation: Department of Pediatric Cardiothoracic Surgery, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Li-sheng
authors.initials: LS
authors.lastname: Qiu
authors.forename: Yan-juan
authors.initials: YJ
authors.lastname: Sun
authors.forename: Jin-fen
authors.initials: JF
authors.lastname: Liu
authors.forename: Li-min
authors.initials: LM
authors.lastname: Zhu
authors.forename: Zhi-wei
authors.initials: ZW
authors.lastname: Xu
mesh_terms: D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome; D014339:Truncus Arteriosus, Persistent / Q000601:surgery*