title: Imiquimod 5% cream treatment for rapidly progressive genital condyloma in a 3-year-old girl.
abstract: BACKGROUND
  The incidence of genital warts in children has increased in the last 50 years. Although pediatric genital warts may resolve spontaneously, the treatment of extensive perianal genital warts in children can be challenging. Imiquimod, although not approved in the pediatric population, may avoid the pain or extensive scarring associated with other treatment modalities.
  
  
  METHODS
  A 3-year-old female was scheduled for surgical resection of genital warts. At surgery, she had extensive condylomas that had progressed rapidly from initial presentation. They were not amenable to surgical treatment due to concerns of incomplete resection, post-operative pain, and genital scarring. After 6 weeks of imiquimod treatment, the condylomatous lesions had completely resolved with minimal side effects.
  
  
  CONCLUSIONS
  Imiquimod 5% cream is an effective treatment option for children with extensive and rapidly progressive perianal warts and is associated with minimal side effects. Its use should be considered in children with extensive condyloma in order to avoid the pain and possible scarring associated with other approved treatment modalities.
authors.affiliation: Department of Obstetrics, Gynaecology, and Newborn Care, The University of Ottawa, Ottawa, Canada.
authors.forename: Emily
authors.initials: E
authors.lastname: Leclair
authors.forename: Amanda
authors.initials: A
authors.lastname: Black
authors.forename: Nathalie
authors.initials: N
authors.lastname: Fleming
mesh_terms: D000634:Aminoquinolines / Q000008:administration & dosage / Q000627:therapeutic use*; D002675:Child, Preschool; D003218:Condylomata Acuminata / Q000188:drug therapy*; D005260:Female; D006801:Humans; D000077271:Imiquimod; D007369:Interferon Inducers / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000634:Aminoquinolines; D007369:Interferon Inducers; D000077271:Imiquimod