title: The molecular biogeochemistry of manganese(II) oxidation.
abstract: Micro-organisms capable of oxidizing the redox-active transition metal manganese play an important role in the biogeochemical cycle of manganese. In the present mini-review, we focus specifically on Mn(II)-oxidizing bacteria. The mechanisms by which bacteria oxidize Mn(II) include a two-electron oxidation reaction catalysed by a novel multicopper oxidase that produces Mn(IV) oxides as the primary product. Bacteria also produce organic ligands, such as siderophores, that bind to and stabilize Mn(III). The realization that this stabilized Mn(III) is present in many environments and can affect the redox cycles of other elements such as sulfur has made it clear that manganese and the bacteria that oxidize it profoundly affect the Earth's biogeochemistry.
authors.affiliation: Division of Environmental and Biomolecular Systems, Oregon Health & Science University, 20000 NW Walker Road, Beaverton, OR 97205, USA.
authors.forename: Kati
authors.initials: K
authors.lastname: Geszvain
authors.forename: Cristina
authors.initials: C
authors.lastname: Butterfield
authors.forename: Richard E
authors.initials: RE
authors.lastname: Davis
authors.forename: Andrew S
authors.initials: AS
authors.lastname: Madison
authors.forename: Sung-Woo
authors.initials: SW
authors.lastname: Lee
authors.forename: Dorothy L
authors.initials: DL
authors.lastname: Parker
authors.forename: Alexandra
authors.initials: A
authors.lastname: Soldatova
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Spiro
authors.forename: George W
authors.initials: GW
authors.lastname: Luther
authors.forename: Bradley M
authors.initials: BM
authors.lastname: Tebo
mesh_terms: D020816:Amino Acid Motifs; D001426:Bacterial Proteins / Q000737:chemistry / Q000502:physiology; D001665:Binding Sites; D017124:Conserved Sequence; D006094:Gram-Positive Bacteria / Q000201:enzymology / Q000378:metabolism*; D017895:Manganese Compounds / Q000378:metabolism*; D010084:Oxidation-Reduction; D010087:Oxides / Q000378:metabolism*; D010088:Oxidoreductases / Q000737:chemistry / Q000502:physiology; D017434:Protein Structure, Tertiary; D020560:Proteobacteria / Q000201:enzymology / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D017895:Manganese Compounds; D010087:Oxides; C027424:manganese oxide; D010088:Oxidoreductases