title: [Results of a structural diagnosis of patients with chronic dyspnoea recruited from two cardiological practices].
abstract: While well validated algorithms exist for the diagnosis of patients with acute dyspnoea, such generally valid procedural instructions are lacking for patients with chronic dyspnoea. The diagnostic approach presented here is based on investigations of 246 patients with chronic dyspnoea recruited from two cardiological practices using a self-developed multi-level procedure. Besides anamnestic and clinical examinations, different diagnostic procedures, available in the ambulant range, are included. The results suggest that in over 50 % of the cases the cause of chronic dyspnoea can be determined from anamnestic and clinical examinations as well as from electrocardiogram and echocardiography. Additional inclusion of lung function and capillary blood gas analysis permitted a sufficient clarification in over 80 % of the cases. In a further step, cardiopulmonary exercise testing clarified the reasons for chronic dyspnoea in approximately 10 % of the remaining patients. Threshold values of lung function parameters as used for the differentiation of acute dyspnoea, do not seem suitable for the diagnosis of patients with chronic dyspnoea. By means of a simple step-wise diagnostic algorithm, applicable under ambulant conditions, the cause of chronic dyspnoea could sufficiently be clarified in more than 95 % of the cases.
authors.affiliation: Universitätsmedizin Greifswald, Klinik für Innere Medizin B. ewert@uni-greifswald.de
authors.forename: R
authors.initials: R
authors.lastname: Ewert
authors.forename: A
authors.initials: A
authors.lastname: Obst
authors.forename: C
authors.initials: C
authors.lastname: Bahr
authors.forename: C
authors.initials: C
authors.lastname: Weirich
authors.forename: F
authors.initials: F
authors.lastname: Henschel
authors.forename: A
authors.initials: A
authors.lastname: Rink
mesh_terms: D000368:Aged; D000465:Algorithms; D002309:Cardiology / Q000706:statistics & numerical data*; D002908:Chronic Disease; D004417:Dyspnea / Q000175:diagnosis* / Q000453:epidemiology*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D015995:Prevalence; D015203:Reproducibility of Results; D012129:Respiratory Function Tests / Q000379:methods / Q000706:statistics & numerical data*; D018570:Risk Assessment / Q000379:methods; D012680:Sensitivity and Specificity