title: The world of LeGoo assessed: a short systematic and critical review.
abstract: It is very difficult to identify whether the use of the thermosensitive polymer LeGoo offers advantages over the use of clamps or clampless techniques for infra-inguinal bypass. This issue of the journal provides much additional information about the use of LeGoo. We have summarised all the available evidence. In a very heterogeneous patient population, with heterogeneous graft type and location, the primary technical success rate remains high at 90% [95%CI 83-99], the 3 months secondary graft patency is 71 [95%CI 58-84]% and limb salvage is 78% [95%CI 68-89]%. These promising early results need to be followed by extended follow up of the patients and standardised outcome reporting in the future.
authors.affiliation: Vascular Surgery, Imperial College at Charing Cross, London W6 8RP, United Kingdom. j.shalhoub@imperial.ac.uk
authors.forename: J
authors.initials: J
authors.lastname: Shalhoub
authors.forename: R J
authors.initials: RJ
authors.lastname: Hinchliffe
authors.forename: J T
authors.initials: JT
authors.lastname: Powell
mesh_terms: D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001831:Body Temperature; D003250:Constriction; D017128:Embolectomy; D004617:Embolism / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D006083:Graft Occlusion, Vascular / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D023821:Limb Salvage; D058729:Peripheral Arterial Disease / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D020442:Poloxamer / Q000009:adverse effects / Q000737:chemistry / Q000627:therapeutic use*; D012086:Reoperation; D016896:Treatment Outcome; D058017:Vascular Grafting / Q000009:adverse effects / Q000401:mortality; D014654:Vascular Patency
chemical_list: C539704:LeGoo; D020442:Poloxamer