title: Chronic venous ulceration of leg associated with peripheral arterial disease: an underappreciated entity in developing country.
abstract: Chronic venous ulcer can often be associated with asymptomatic peripheral arterial disease (PAD), which usually remains undiagnosed adding significantly to the morbidity of these patients. The Ankle-Brachial Pressure Index (ABPI) is suggested for PAD evaluation. Many PAD studies were conducted in western countries, but there is a scarcity of data on the prevalence of PAD in clinical venous ulcer patient in developing countries. We conducted a study in a tertiary care hospital of eastern part of India to find out the prevalence of PAD in venous ulcer patients, and also to find the sensitivity of ABPI as a diagnostic tool in these patients. We evaluated clinically diagnosed patients with venous ulcer using ABPI and Colour Doppler study for the presence of PAD. Possible associations such as age, sex, body mass index (BMI), smoking, hypertension and atherosclerosis were studied. All results were analysed using the software Statistica version 6. PAD was present in 23 (27·71%) patients. Older age, longer duration, smoking, high BMI and hypertension were found to be significantly associated with PAD. A very strong level of agreement was found between venous Doppler and ABPI. Assessment for the presence of PAD is important in all clinically diagnosed venous ulcer patients. ABPI being a simple, non-invasive outpatient department (OPD)-based procedure, can be routinely used in cases of venous ulcer to find out the hidden cases of PAD even in developing countries.
authors.affiliation: Department of Dermatology, IPGMER & SSKM Hospital, Kolkatta, West Bengal, India.
authors.forename: Falguni
authors.initials: F
authors.lastname: Nag
authors.forename: Abhishek
authors.initials: A
authors.lastname: De
authors.forename: Avijit
authors.initials: A
authors.lastname: Hazra
authors.forename: Gobinda
authors.initials: G
authors.lastname: Chatterjee
authors.forename: Arghyaprasun
authors.initials: A
authors.lastname: Ghosh
authors.forename: Trupti V
authors.initials: TV
authors.lastname: Surana
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D055109:Ankle Brachial Index; D002908:Chronic Disease / Q000453:epidemiology; D003906:Developing Countries / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D007871:Leg Ulcer / Q000175:diagnosis* / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D058729:Peripheral Arterial Disease / Q000175:diagnosis* / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D014647:Varicose Ulcer / Q000175:diagnosis* / Q000453:epidemiology*