title: Catastrophic antiphospholipid antibody syndrome in a child with thrombotic microangiopathy.
abstract: Thrombotic microangiopathic hemolytic anemia (TMHA) is not uncommon in clinical nephrology practice while antiphospholipid syndrome (APS) is uncommon. Although less than 1% of patients with APS develop catastrophic APS (CAPS), its potential lethal outcome because of thrombosis in multiple organs and subsequent multiorgan failure emphasizes its importance in nephrology practice. Here is a case of catastrophic APS in a 7-year-old girl, who presented to us with TMHA associated with antiphospholipid antibodies and subsequently died because of CAPS.
authors.affiliation: Department of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
authors.forename: N
authors.initials: N
authors.lastname: Prasad
authors.forename: D
authors.initials: D
authors.lastname: Bhadauria
authors.forename: N
authors.initials: N
authors.lastname: Agarwal
authors.forename: A
authors.initials: A
authors.lastname: Gupta
authors.forename: P
authors.initials: P
authors.lastname: Gupta
authors.forename: M
authors.initials: M
authors.lastname: Jain
authors.forename: H
authors.initials: H
authors.lastname: Lal