title: Two new chromone glycosides from Drynaria fortunei.
abstract: Two new chromone glycosides, drynachromoside A (1), drynachromoside B (2), along with three known flavanones, 5,7,3',5'-tetrahydroxy-flavanone (3), 5,7,3',5'-tetrahydroxy-flavanone-7-O-β-d-glucopyranoside (4), and 5,7,3',5'-tetrahydroxy-flavanone-7-O-neohesperidoside (5), were isolated from the dry rhizomes of Drynaria fortunei by means of bio-active screening. The two former compounds were elucidated on the basis of physico-chemical property and spectroscopic data. The osteoblastic proliferation activities of these flavonoids were evaluated by the method of MTT. The results showed that compound 1 exhibited the biochemical effects on the proliferation of MC3T3-E1 cells, while Compound 2 showed inhibitory effects against MC3T3-E1 cells.
authors.affiliation: Department of Pharmacy, General Hospital of Shenyang Military Area Command, Shenyang 110840, China.
authors.forename: Zhen-Ping
authors.initials: ZP
authors.lastname: Shang
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Meng
authors.forename: Qing-Chun
authors.initials: QC
authors.lastname: Zhao
authors.forename: Ming-Zhi
authors.initials: MZ
authors.lastname: Su
authors.forename: Zhou
authors.initials: Z
authors.lastname: Luo
authors.forename: Lin
authors.initials: L
authors.lastname: Yang
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Tan
mesh_terms: D016475:3T3 Cells; D000818:Animals; D002867:Chromones / Q000737:chemistry*; D006027:Glycosides / Q000737:chemistry*; D051379:Mice; D015394:Molecular Structure; D029621:Polypodiaceae / Q000737:chemistry*; D027343:Rhizome
chemical_list: D002867:Chromones; D006027:Glycosides; C582254:drynachromoside A; C582253:drynachromoside B