title: Metastatic haematological malignancy presenting as a sellar mass.
abstract: A man in his 60s with a history of multiple myeloma diagnosed 6&emsp14;months previously was referred with a diagnosis of a sellar mass. He reported a 3-month history of headaches associated with double vision which appeared to improve with corticosteroid treatment. An MRI scan revealed a 3.7 cm × 3 cm × 2.6 cm sellar mass with erosion into the sphenoid sinus and extending to the right cavernous sinus. Pituitary function tests were normal apart from hypogonadotrophic hypogonadism. A diagnosis of plasmacytoma was considered and so transphenoidal biopsy of the sellar lesion was organised, which revealed sheets of mature appearing plasma cells, staining exclusively for κ-light chain immunoglobulins. He was to be started on chemotherapy for the myeloma and radiotherapy for the plasmacytoma. The patient's clinical course was complicated by community-acquired pneumonia and renal failure resulting in his death a month after the diagnosis of plasmacytoma.
authors.affiliation: Centre for Endocrine and Diabetes Sciences, University Hospital of Wales, Cardiff, UK. man1210@yahoo.com
authors.forename: Maneesh
authors.initials: M
authors.lastname: Udiawar
authors.forename: Christina
authors.initials: C
authors.lastname: Bejnariu
authors.forename: Stephen
authors.initials: S
authors.lastname: Davies
mesh_terms: D001706:Biopsy; D003388:Cranial Fossa, Posterior / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D009361:Neoplasm Invasiveness; D010901:Pituitary Function Tests; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D010954:Plasmacytoma / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D012658:Sella Turcica / Q000473:pathology; D013101:Sphenoid Sinus / Q000473:pathology; D014057:Tomography, X-Ray Computed