title: Intrinsically copper-64-labeled organic nanoparticles as radiotracers.
abstract: PET friendly: labels for PET imaging are incorporated into completely organic porphysomes by using a fast (30 min), one-pot, high-yielding (>95 %) procedure to produce highly stable (>48 h) radiolabeled nanoparticles that show the highest specific activity ever reported for a (64) Cu-labeled nanoparticle. These (64) Cu-porphysomes can be accurately and noninvasively tracked in vivo.
authors.affiliation: Ontario Cancer Institute, Campbell Family Institute for Cancer Research, UHN, Canada.
authors.forename: Tracy W
authors.initials: TW
authors.lastname: Liu
authors.forename: Thomas D
authors.initials: TD
authors.lastname: MacDonald
authors.forename: Jiyun
authors.initials: J
authors.lastname: Shi
authors.forename: Brian C
authors.initials: BC
authors.lastname: Wilson
authors.forename: Gang
authors.initials: G
authors.lastname: Zheng
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D003287:Contrast Media / Q000138:chemical synthesis / Q000737:chemistry; D003300:Copper / Q000737:chemistry*; D003301:Copper Radioisotopes / Q000737:chemistry; D004195:Disease Models, Animal; D006801:Humans; D008297:Male; D053768:Metal Nanoparticles / Q000737:chemistry*; D051379:Mice; D011166:Porphyrins / Q000737:chemistry; D049268:Positron-Emission Tomography; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging; D019275:Radiopharmaceuticals / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D003287:Contrast Media; D003301:Copper Radioisotopes; D011166:Porphyrins; D019275:Radiopharmaceuticals; D003300:Copper