title: Biosynthetic porcine collagen dressings as an adjunct or definitive tool for the closure of scalp defects without periosteum.
abstract: BACKGROUND
  Aggressive carcinomas of the scalp usually occur in elderly patients with multiple comorbidities. Complete excision of this type of tumor often involves the removal of periosteum, and the resulting defects can be difficult to reconstruct.
  
  
  OBJECTIVE
  To evaluate the usefulness of porcine type I collagen dressings as adjunct or definitive treatment in the surgical closure of scalp defects without periosteum.
  
  
  METHODS
  We performed a prospective study between January 2009 and November 2011 of patients with scalp defects larger than 5cm resulting from surgery that required the removal of periosteum to obtain tumor-free margins.
  
  
  RESULTS
  The most prevalent type of tumor was recurrent cutaneous squamous cell carcinoma. The surgical defects ranged in diameter from 5 to 7cm. In 100% of the patients who received a graft after dressing removal (n=4), the graft took well. In the patients in whom the biosynthetic dressing was definitive (n=6), granulation tissue filled the defect and complete closure was achieved in approximately 3.5 months.
  
  
  CONCLUSIONS
  The use of porcine type I collagen dressings as an adjunct or definitive tool for the closure of surgical defects on the scalp measuring more than 5cm in which periosteum has been removed proved to be simple, inexpensive, and effective.
authors.affiliation: Departamento de dermatología, Hospital de Manises, Valencia, Spain. antmarto@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Martorell-Calatayud
authors.forename: V
authors.initials: V
authors.lastname: Sanz-Motilva
authors.forename: E
authors.initials: E
authors.lastname: Nagore
authors.forename: C
authors.initials: C
authors.lastname: Serra-Guillén
authors.forename: O
authors.initials: O
authors.lastname: Sanmartín
authors.forename: B
authors.initials: B
authors.lastname: Echeverría
authors.forename: C
authors.initials: C
authors.lastname: Guillén-Barona
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001672:Biocompatible Materials; D020099:Coated Materials, Biocompatible; D003094:Collagen; D003131:Combined Modality Therapy; D005260:Female; D006258:Head and Neck Neoplasms / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009779:Occlusive Dressings; D010521:Periosteum / Q000601:surgery; D011446:Prospective Studies; D019651:Plastic Surgery Procedures / Q000379:methods; D012535:Scalp / Q000601:surgery*; D012878:Skin Neoplasms / Q000601:surgery*; D013552:Swine; D058106:Wound Closure Techniques
chemical_list: C042816:Biobrane; D001672:Biocompatible Materials; D020099:Coated Materials, Biocompatible; D003094:Collagen