title: Angiogenesis-related microRNAs in colon cancer.
abstract: BACKGROUND
  Angiogenesis, for its fundamental role in cancer growth and metastasis, has become an appealing target in cancer therapy. A number of angiogenesis-related microRNAs (miRNAs) are under investigation and they can affect the cancerous phenotype of malignant cells.
  
  
  METHODS
  The authors review the recent advances in angiogenesis-related miRNAs in human colon cancer. They also envisage future developments toward potential miRNA-based applications to cancer treatment.
  
  
  CONCLUSIONS
  Angiogenesis-related miRNAs may reasonably be considered as a valuable cancer therapeutic tool. More investigations should be performed to promote therapeutic-clinical research of miRNAs in patients with colon cancer.
authors.affiliation: Fourth Military Medical University, Xijing Hospital of Digestive Diseases, State Key Laboratory of Cancer Biology, Shaanxi Province, China. hongliu180@126.com
authors.forename: Liu
authors.initials: L
authors.lastname: Hong
authors.forename: Yu
authors.initials: Y
authors.lastname: Han
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhou
authors.forename: Ahuja
authors.initials: A
authors.lastname: Nita
mesh_terms: D003110:Colonic Neoplasms / Q000098:blood supply* / Q000235:genetics; D006801:Humans; D035683:MicroRNAs / Q000235:genetics*; D009389:Neovascularization, Pathologic / Q000235:genetics*
chemical_list: D035683:MicroRNAs