title: 5(4H)-oxazolones as intermediates in the carbodiimide- and cyanamide-promoted peptide activations in aqueous solution.
abstract: The early days: although considered a species to be avoided in peptide chemistry, the intermediacy of 5(4H)-oxazolones is demonstrated to be essential for the formation of peptides through cyanamide and carbodiimide activation in aqueous solution.
authors.affiliation: Spectrométries et Dynamique Moléculaire, Physique des Interactions Ioniques et Moléculaires, UMR, CNRS-Aix-Marseille Université, France. gregoire.danger@univ-amu.fr
authors.forename: Grégoire
authors.initials: G
authors.lastname: Danger
authors.forename: Arthur
authors.initials: A
authors.lastname: Michaut
authors.forename: Manon
authors.initials: M
authors.lastname: Bucchi
authors.forename: Laurent
authors.initials: L
authors.lastname: Boiteau
authors.forename: Justine
authors.initials: J
authors.lastname: Canal
authors.forename: Raphaël
authors.initials: R
authors.lastname: Plasson
authors.forename: Robert
authors.initials: R
authors.lastname: Pascal
mesh_terms: D002234:Carbodiimides / Q000737:chemistry*; D003484:Cyanamide / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D010081:Oxazolone / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D012996:Solutions / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D002234:Carbodiimides; D010455:Peptides; D012996:Solutions; D014867:Water; D010081:Oxazolone; D003484:Cyanamide