title: Can the reinforcing value of food be measured in bulimia nervosa?
abstract: Binge eating is a core clinical feature of bulimia nervosa (BN). Enhanced reinforcing value of food may play a role in this behavioral disturbance, but a systematic behavioral assessment of objective measures of the rewarding value of binge eating is lacking. The purpose of this study was to quantify the reinforcing value of food in BN patients as compared with normal controls. A progressive ratio (PR) computerized work task was completed under binge and non-binge instruction. The task consisted of 12 trials. The first trial required 50 keyboard taps to earn one portion of yogurt shake, and subsequent trials required progressive work increments of 200 taps for each additional portion. Completion of all 12 trials required 13,800 taps to earn 2100ml of shake. The breakpoint, defined as the largest ratio completed before a participant stopped working, was the measure of reinforcing efficacy. Ten patients and 10 controls completed the experiment. Under binge instruction, patients completed more trials and taps, and had a higher breakpoint than controls. The non-binge instruction yielded opposite findings; compared to controls, patients completed fewer trials and taps, and had a lower breakpoint. These results support the feasibility and potential utility of a PR task to quantify the reinforcing value of food in patients with BN.
authors.affiliation: New York State Psychiatric Institute, 1051 Riverside Drive, Unit 98, New York, NY 10032, USA. js2202@columbia.edu
authors.forename: Janet
authors.initials: J
authors.lastname: Schebendach
authors.forename: Allegra
authors.initials: A
authors.lastname: Broft
authors.forename: Richard W
authors.initials: RW
authors.lastname: Foltin
authors.forename: B Timothy
authors.initials: BT
authors.lastname: Walsh
mesh_terms: D000328:Adult; D056912:Binge-Eating Disorder / Q000523:psychology*; D002032:Bulimia / Q000523:psychology*; D052018:Bulimia Nervosa / Q000523:psychology*; D004032:Diet; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D012201:Reward; D014937:Work; D015014:Yogurt; D055815:Young Adult