title: Retinal fundus imaging in mouse models of retinal diseases.
abstract: The development of in vivo retinal fundus imaging in mice has opened a new research horizon, not only in ophthalmic research. The ability to monitor the dynamics of vascular and cellular changes in pathological conditions, such as neovascularization or degeneration, longitudinally without the need to sacrifice the mouse, permits longer observation periods in the same animal. With the application of the high-resolution confocal scanning laser ophthalmoscopy in experimental mouse models, access to a large spectrum of imaging modalities in vivo is provided.
authors.affiliation: Department of Ophthalmology, Westfaelische Wilhelms-University Münster, Münster, Germany.
authors.forename: Anne F
authors.initials: AF
authors.lastname: Alex
authors.forename: Peter
authors.initials: P
authors.lastname: Heiduschka
authors.forename: Nicole
authors.initials: N
authors.lastname: Eter
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004867:Equipment Design; D005451:Fluorescein Angiography / Q000295:instrumentation / Q000379:methods*; D005654:Fundus Oculi; D051379:Mice; D019721:Ophthalmoscopes; D009887:Ophthalmoscopy / Q000379:methods*; D012160:Retina / Q000473:pathology*; D012164:Retinal Diseases / Q000473:pathology*; D015861:Retinal Neovascularization / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*