title: Better tools for assessing osteoporosis.
abstract: Some 30 years ago, we applied the newly described method of dual photon absorptiometry (DPA) to demonstrate that osteoporotic women with vertebral fractures had lost substantially more bone from the vertebrae than controls. This opened a whole new field of research into the determinants of bone loss and fractures in the axial skeleton and set the stage for subsequent development of dual-energy x-ray absorptiometry (DXA) and quantitative computed tomography (QCT), which are now the standard methods for assessing osteoporosis severity and treatment efficacy.
authors.affiliation: Endocrine Research Unit, College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
authors.forename: B Lawrence
authors.initials: BL
authors.lastname: Riggs
authors.forename: Sundeep
authors.initials: S
authors.lastname: Khosla
authors.forename: L Joseph
authors.initials: LJ
authors.lastname: Melton
mesh_terms: D015502:Absorptiometry, Photon / Q000266:history; D015519:Bone Density; D049672:History, 19th Century; D006801:Humans; D010024:Osteoporosis / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000266:history