title: Clinical evaluation of application of polyglycolic acid sheet and fibrin glue spray for partial glossectomy.
abstract: OBJECTIVE
  The aim of this study was to evaluate the usefulness of covering open wounds with a polyglycolic acid (PGA) sheet and a fibrin glue spray after partial glossectomy.
  
  
  METHODS
  We clinically evaluated postoperative pain and scar contracture in 44 patients who underwent partial glossectomy followed by covering with a PGA sheet and a fibrin glue spray (PGA sheet group), as compared with 29 patients who were closed primarily (primary closure group).
  
  
  RESULTS
  Duration of nonsteroidal anti-inflammatory drugs was almost the same between the PGA sheet group and the primary closure group. The degree of scar contracture was mild in many cases in both groups. In the case in which the excision area was wide and depth was shallow, there was a tendency for the scar contracture to be less in the PGA sheet group.
  
  
  CONCLUSIONS
  Our findings showed that the use of a PGA sheet and fibrin glue spray for open wounds resulting from partial glossectomy was useful in terms of rapid relief from postoperative pain and prevention of scar contracture.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan. jtakeu@med.kobe-u.ac.jp
authors.forename: Junichiro
authors.initials: J
authors.lastname: Takeuchi
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Suzuki
authors.forename: Maho
authors.initials: M
authors.lastname: Murata
authors.forename: Yasumasa
authors.initials: Y
authors.lastname: Kakei
authors.forename: Shinshou
authors.initials: S
authors.lastname: Ri
authors.forename: Masahiro
authors.initials: M
authors.lastname: Umeda
authors.forename: Takahide
authors.initials: T
authors.lastname: Komori
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001672:Biocompatible Materials / Q000737:chemistry*; D002278:Carcinoma in Situ / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D002921:Cicatrix / Q000517:prevention & control; D003286:Contracture / Q000517:prevention & control; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D005927:Glossectomy / Q000379:methods*; D006801:Humans; D007972:Leukoplakia, Oral / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010149:Postoperative Pain / Q000517:prevention & control; D011100:Polyglycolic Acid / Q000737:chemistry*; D062326:Re-Epithelialization / Q000502:physiology; D013526:Surgical Mesh; D013997:Time Factors; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014062:Tongue Neoplasms / Q000601:surgery; D058106:Wound Closure Techniques / Q000295:instrumentation*; D055815:Young Adult
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001672:Biocompatible Materials; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; D011100:Polyglycolic Acid