title: [Contraception and bone health in adolescence].
abstract: Adolescents' access to contraception has improved and indication for their use have been extended beyond pregnancy prevention. For adolescents, this implies the use of hormonal contraception before the accrual of peak bone mass. Sexual hormones, notably estrogens, play a major role in skeletal development, growth and acquisition of maximal bone mass density (BMD). This article will review different contraceptive methods and their impact on BMD, with particular attention to low-dose pills and medroxyprogesterone acetate, both of which seem to alter peak bone mass acquisition. Nevertheless, benefits from appropriate contraception should be weighed against safety concerns, and recommended on an individual basis.
authors.affiliation: Service de gynécologie, Département de gynécologie et obstétrique, HUG, 1211 Genève 14. olivier.julen@hcuge.ch
authors.forename: Olivier
authors.initials: O
authors.lastname: Julen
authors.forename: Sophie
authors.initials: S
authors.lastname: Larigaldie
authors.forename: Michal
authors.initials: M
authors.lastname: Yaron
mesh_terms: D000293:Adolescent; D015519:Bone Density / Q000187:drug effects*; D001846:Bone Development / Q000187:drug effects; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects*; D005260:Female; D006801:Humans
chemical_list: D003278:Contraceptives, Oral, Hormonal