title: Isotretinoin for the treatment of granulomatous rosacea: case report and review of the literature.
abstract: BACKGROUND
  Granulomatous rosacea is considered a clinical variant of rosacea and is characterized by hard yellow, brown, red or flesh-colored cutaneous papules or nodules that may be severe and may lead to scarring. The lesions typically appear on the cheeks and periorificial lesions; they are monomorphic in each patient and sit on relatively normal-appearing skin. The diagnosis should be established by excluding other granulomatous disorders and rosacea-like eruptions such as sarcoidosis, tuberculosis, and lupus miliaris disseminatus faciei. The clinical course is chronic and unpredictable, and management can be very difficult.
  
  
  METHODS
  We report the case of a 28-year-old female with granulomatous rosacea who responded successfully to oral isotretinoin. No recurrence was noticed 6 months after the completion of treatment.
authors.affiliation: Department of Dermatology, Veterans Administration Hospital NIMTS, Athens, Greece. efrall@otenet.gr
authors.forename: Efstathios
authors.initials: E
authors.lastname: Rallis
authors.forename: Chrysovalantis
authors.initials: C
authors.lastname: Korfitis
mesh_terms: D000328:Adult; D003879:Dermatologic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015474:Isotretinoin / Q000627:therapeutic use*; D012393:Rosacea / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D003879:Dermatologic Agents; D015474:Isotretinoin