title: [Evaluation of graft perfusion in patients with ischemic-type of biliary lesions after liver transplantation].
abstract: OBJECTIVE
  To investigate the value of 320-rows CT perfusion (CTP) imaging in the study of hepatic hemodynamic characters in ischemic-type biliary lesions (ITBL) after liver transplantation.
  
  
  METHODS
  A total of 11 ITBL patients received 320-slice CT angiography (CTA) and CTP after liver transplantation scheduled at 5-10 min away. Four patients underwent liver biopsy While 7 patients with normal liver after transplantation were selected as the control group. The parameters of hepatic artery perfusion (HAP), portal vein perfusion (PVP), total hepatic perfusion (TLP) and hepatic arterial perfusion index (HPI) were measured and compared for all patients. And the blood perfusion characters of liver with ITBL after transplantation were analyzed.
  
  
  RESULTS
  (1) In 11 ITBL patients, 3 patients had no vascular complications on CTA, 1 with simple hepatic artery stenosis (HAS), 1 with HAS and arterioportal shunt (APS), 2 with HAS and portal vein stenosis/right hepatic vein stenosis (PVS/RHVS), 1 with simple APS, 2 with simple PVS and 1 with portal vein thrombosis and cavernous transformation of portal vein (PVT and CTPV). And 4/11 patients underwent liver biopsy, 2 in which confirmed mild acute rejection and 2 confirmed biliary obstruction associated with ascending biliary infection.(2) HAP of the ITBL and control groups were (66 ± 38) and (40 ± 8) ml×min(-1)·(100 ml)(-1), PVP (128 ± 35) and (163 ± 21) ml×min(-1)·(100 ml)(-1), TLP (194 ± 58) and (203 ± 19) ml×min(-1)·(100 ml)(-1), HPI 34% ± 14% and 21% ± 4% respectively. The differences in the value of HAP, PVP and HPI between the groups were statistically significant (P < 0.05) excluding TLP.
  
  
  CONCLUSIONS
  Various liver perfusion abnormalities of ITBL may be evaluated objectively by CTP. ITBL might occurred when HAP and HPI increased with a decreased of PVP.
authors.affiliation: Department of Radiology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou 510630, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Fang
authors.forename: Xiao-chun
authors.initials: XC
authors.lastname: Meng
authors.forename: Jie
authors.initials: J
authors.lastname: Qin
authors.forename: Kang-shun
authors.initials: KS
authors.lastname: Zhu
authors.forename: Pei-yi
authors.initials: PY
authors.lastname: Xie
authors.forename: Li
authors.initials: L
authors.lastname: Quan
authors.forename: Hong
authors.initials: H
authors.lastname: Shan
mesh_terms: D000328:Adult; D000368:Aged; D001649:Bile Duct Diseases / Q000000981:diagnostic imaging* / Q000209:etiology; D001659:Biliary Tract / Q000098:blood supply; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007511:Ischemia; D016031:Liver Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*