title: [The study in detection of microcalcification in early breast cancer by ultrasound and its correlation with pathohistology].
abstract: OBJECTIVE
  To discuss the role of ultrasound in examining microcalcification of early breast cancer and its correlation with pathohistological type and grade.
  
  
  METHODS
  178 lesions in 165 cases of early breast cancer confirmed by pathology after surgical resection were examine by high frequency ultrasound, meanwhile microcalcification were detected and reported. 39 lesions in 32 cases are carcinoma in situ and microinvasive carcinoma of breast. 139 lesions in 133 cases are early invasive breast carcinoma that is below 2 cm in diameter and doesn't invasive the lymph node and other parts of the body. To analyse the sensitivity of detection micro-calcification of early breast cancer by ultrasound and its correlation with pathohistological type and grade.
  
  
  RESULTS
  The sensitivity is 81.6% in detecting microcalcification of early breast cancer by ultrasound. There is no significant statistical difference in detecting microcalcification between the two group (P = 0.217). There is no significant statistical difference in detecting microcalcification of early invasive breast cancer between the different pathologic types (P > 0.05), and there are no significant differences in detecting microcalcification of early breast cancer between the different pathologic grades (group I: P = 0.202, group II: P = 0.415). There is significant difference in detecting microcalcification of solid tumor by ultrasonic examination in group I between the different pathologic grades (P = 0.029).
  
  
  CONCLUSIONS
  There is higher sensitivity in detecting microcalcification of early breast cancer by ultrasonography. Microcalcification of early breast cancer may be no closely related to pathologic grades. US has a certain value to clinic in detecting microcalcification of early breast cancer.
authors.affiliation: Department of Ultrasonogragraphy, Beijing Hospital, Beijing, China. hxiujie2000@yahoo.com.cn
authors.forename: Xiu-jie
authors.initials: XJ
authors.lastname: Han
authors.forename: Jun-hong
authors.initials: JH
authors.lastname: Ren
authors.forename: Na
authors.initials: N
authors.lastname: Ma
authors.forename: Qing-ting
authors.initials: QT
authors.lastname: Tan
authors.forename: Si-yu
authors.initials: SY
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014463:Ultrasonography