title: Development of a sampling strategy and sample size calculation to estimate the distribution of mammographic breast density in Korean women.
abstract: Mammographic breast density is a known risk factor for breast cancer. To conduct a survey to estimate the distribution of mammographic breast density in Korean women, appropriate sampling strategies for representative and efficient sampling design were evaluated through simulation. Using the target population from the National Cancer Screening Programme (NCSP) for breast cancer in 2009, we verified the distribution estimate by repeating the simulation 1,000 times using stratified random sampling to investigate the distribution of breast density of 1,340,362 women. According to the simulation results, using a sampling design stratifying the nation into three groups (metropolitan, urban, and rural), with a total sample size of 4,000, we estimated the distribution of breast density in Korean women at a level of 0.01% tolerance. Based on the results of our study, a nationwide survey for estimating the distribution of mammographic breast density among Korean women can be conducted efficiently.
authors.affiliation: National Cancer Control Institute, National Cancer Center, Goyang, Korea. jkjun@ncc.re.kr
authors.forename: Jae Kwan
authors.initials: JK
authors.lastname: Jun
authors.forename: Mi Jin
authors.initials: MJ
authors.lastname: Kim
authors.forename: Kui Son
authors.initials: KS
authors.lastname: Choi
authors.forename: Mina
authors.initials: M
authors.lastname: Suh
authors.forename: Kyu-Won
authors.initials: KW
authors.lastname: Jung
mesh_terms: D000328:Adult; D000368:Aged; D001940:Breast / Q000033:anatomy & histology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D056910:Republic of Korea; D012107:Research Design; D012307:Risk Factors; D012424:Rural Population / Q000706:statistics & numerical data; D018401:Sample Size; D014505:Urban Population / Q000706:statistics & numerical data