title: Potential intracranial applications of magnetic resonance-guided focused ultrasound surgery.
abstract: Magnetic resonance-guided focused ultrasound surgery (MRgFUS) has the potential to create a shift in the treatment paradigm of several intracranial disorders. High-resolution MRI guidance combined with an accurate method of delivering high doses of transcranial ultrasound energy to a discrete focal point has led to the exploration of noninvasive treatments for diseases traditionally treated by invasive surgical procedures. In this review, the authors examine the current intracranial applications under investigation and explore other potential uses for MRgFUS in the intracranial space based on their initial cadaveric studies.
authors.affiliation: Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA. SJM9N@hscmail.mcc.virginia.edu
authors.forename: Stephen
authors.initials: S
authors.lastname: Monteith
authors.forename: Jason
authors.initials: J
authors.lastname: Sheehan
authors.forename: Ricky
authors.initials: R
authors.lastname: Medel
authors.forename: Max
authors.initials: M
authors.lastname: Wintermark
authors.forename: Matthew
authors.initials: M
authors.lastname: Eames
authors.forename: John
authors.initials: J
authors.lastname: Snell
authors.forename: Neal F
authors.initials: NF
authors.lastname: Kassell
authors.forename: W Jeff
authors.initials: WJ
authors.lastname: Elias
mesh_terms: D001927:Brain Diseases / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods / Q000639:trends*; D017131:Thrombectomy / Q000295:instrumentation / Q000379:methods / Q000639:trends*; D059708:Ultrasonic Surgical Procedures / Q000295:instrumentation / Q000379:methods / Q000639:trends*