title: [Study of the pragmatic of saliva test cassette to detect the Helicobacter pylori in oral cavity].
abstract: OBJECTIVE
  To study the link of Helicobacter pylori salive test cassette (HPS) and 13C-urea breath test (13C-UBT) on detecting Helicobacter pylori infection of stomach, and the sensitivity as well as specificity should be determined.
  
  
  METHODS
  A screening trial of 13C-UBT and HPS tests was carried out 130 patients included 106 positive and 24 negative results of 13C-UBT. As gold standards of 13C-UBT, a comparison study with HPS was evaluated using Bayes formula.
  
  
  RESULTS
  The sensitivity, specificity, accuracy, positive and negative predictive value of HPS was 68.87%, 58.33%, 66.92%, 87.95%, 29.79% respectively. The coincidence was 66.92%.
  
  
  CONCLUSIONS
  There is a correlation between results of 13C-UBT and HPS. Combination of 13C-UBT and HPS may compensate the blind zone of 13C-UBT in detecting oral Helicobacter pylori infection. 13C-UBT could not be used as a gold standard to judge the validation of HPS in detecting Helicobacter pylori oral infection. The methods can be used at the same time in clinic.
authors.affiliation: Dept. of Stomatology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Wang
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhao
authors.forename: Nan
authors.initials: N
authors.lastname: Chen
authors.forename: Junhong
authors.initials: J
authors.lastname: Wang
authors.forename: Yantong
authors.initials: Y
authors.lastname: Xing
authors.forename: Gengyue
authors.initials: G
authors.lastname: Zhang
mesh_terms: D001499:Bayes Theorem; D001944:Breath Tests; D016481:Helicobacter Infections; D016480:Helicobacter pylori; D006801:Humans; D009055:Mouth; D012463:Saliva; D012680:Sensitivity and Specificity; D014508:Urea
chemical_list: D014508:Urea