title: One-pot synthesis of (3-sulfopropyl methacrylate potassium)-silica hybrid monolith via thiol-ene click chemistry for CEC.
abstract: A novel (3-sulfopropyl methacrylate potassium)-silica hybrid monolithic column for CEC has been prepared by a simple one-pot approach based on efficient thiol-ene click chemistry. In this process, the polycondensation of hydrolyzed alkoxysilanes and in situ click reaction of vinyl groups on 3-sulfopropyl methacrylate potassium and thiol groups on the precondensed siloxanes simultaneously occurred in a pretreated capillary. Homogeneous monolithic matrix with large through-pores tightly bonded to the inner wall of the capillary was shown by optical microscope and SEM. The minimum plate height of this hybrid monolithic column was determined as 3.9 μm for thiourea. Anilines, alkylbenzenes, and phenols were well separated on this hybrid monolithic column by CEC, which indicated typical reversed-phase and cation-exchange chromatographic retention mechanisms of the column.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, PR China.
authors.forename: Huihui
authors.initials: H
authors.lastname: Yang
authors.forename: Yingzhuang
authors.initials: Y
authors.lastname: Chen
authors.forename: Yixuan
authors.initials: Y
authors.lastname: Liu
authors.forename: Lihua
authors.initials: L
authors.lastname: Nie
authors.forename: Shouzhuo
authors.initials: S
authors.lastname: Yao
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry; D001555:Benzene Derivatives / Q000737:chemistry; D053801:Capillary Electrochromatography / Q000295:instrumentation*; D057930:Click Chemistry / Q000379:methods*; D053841:Electroosmosis; D006863:Hydrogen-Ion Concentration; D008689:Methacrylates / Q000138:chemical synthesis* / Q000737:chemistry; D015203:Reproducibility of Results; D012822:Silicon Dioxide / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: C529206:3-sulfopropyl methacrylate; D000814:Aniline Compounds; D001555:Benzene Derivatives; D008689:Methacrylates; D013438:Sulfhydryl Compounds; D012822:Silicon Dioxide; C023650:aniline