title: Extraocular sebaceous carcinoma: a report of 2 cases.
abstract: Sebaceous carcinoma is a rare, aggressive adnexal tumor of unknown etiology; 75% of these tumors arise in the periocular region while 25% arise at extraocular sites. This cutaneous tumor is a diagnostic sign of Muir-Torre syndrome, a disorder associated with visceral malignancies and gene abnormalities. Patients with sebaceous carcinoma should therefore be carefully evaluated; a detailed personal and family history of cancer, a thorough physical examination, additional tests where appropriate, and close monitoring will all be required. We report 2 cases of extraocular sebaceous carcinoma and review the literature, focusing on the association between sebaceous carcinoma and Muir-Torre syndrome.
authors.affiliation: Servicio de Dermatología, Hospital General Universitario Gregorio Marañón, Madrid, Spain. deysycieza@gmail.com
authors.forename: D E
authors.initials: DE
authors.lastname: Cieza-Díaz
authors.forename: N
authors.initials: N
authors.lastname: Cano-Martínez
authors.forename: L
authors.initials: L
authors.lastname: Barchino-Ortiz
authors.forename: I
authors.initials: I
authors.lastname: Longo-Imedio
mesh_terms: D018266:Adenocarcinoma, Sebaceous / Q000150:complications / Q000473:pathology; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008875:Middle Aged; D055653:Muir-Torre Syndrome / Q000150:complications; D012626:Sebaceous Gland Neoplasms / Q000150:complications / Q000473:pathology; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology