title: [Nanoscale tailoring of the surface properties of biomaterials and drug carriers].
abstract: Functionalities of biomaterials and drug delivery systems are improved by tailoring their surface properties using modern nanotechnology. Orthopedic implants and invasive electrodes are examples of implantable biomaterials. Biological interactions of orthopedic implants can be optimized by the synergetic effect of surface micro- and nanotexturing with a chemical composition of coating. Further, mechanical flexibility and electrochemical characteristics of invasive electrodes are improved by using micro- and nanotechnology. In nano-size drug delivery systems, surface properties of nanocarriers strongly affect their safety and efficacy. Mesoporous silicon nanoparticles are example of nanocarriers those properties can be tailored for drug delivery applications.
authors.forename: Kristiina
authors.initials: K
authors.lastname: Järvinen
authors.forename: Jorma
authors.initials: J
authors.lastname: Jokiniemi
authors.forename: Mikko
authors.initials: M
authors.lastname: Lammi
authors.forename: Reijo
authors.initials: R
authors.lastname: Lappalainen
authors.forename: Ale
authors.initials: A
authors.lastname: Närvänen
authors.forename: Tapani A
authors.initials: TA
authors.lastname: Pakkanen
authors.forename: Vesa-Pekka
authors.initials: VP
authors.lastname: Lehto
mesh_terms: D020099:Coated Materials, Biocompatible / Q000737:chemistry; D016503:Drug Delivery Systems; D004566:Electrodes; D053758:Nanoparticles / Q000737:chemistry; D036103:Nanotechnology; D019736:Prostheses and Implants; D012825:Silicon / Q000737:chemistry; D013499:Surface Properties
chemical_list: D020099:Coated Materials, Biocompatible; D012825:Silicon