title: Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors.
abstract: Infiltration of plasma cells is associated with better prognosis in breast, lung and colon cancer. Immunoglobulin κ chain (IGKC) is now available as a single, robust immune marker predicting metastasis-free survival and response to chemotherapy. This will facilitate a deeper understanding of the role of the humoral immune system in cancer development.
authors.affiliation: Department of Obstetrics and Gynecology; University Hospital; Mainz, Germany.
authors.forename: Marcus
authors.initials: M
authors.lastname: Schmidt
authors.forename: Patrick
authors.initials: P
authors.lastname: Micke
authors.forename: Mathias
authors.initials: M
authors.lastname: Gehrmann
authors.forename: Jan G
authors.initials: JG
authors.lastname: Hengstler