title: Respiratory health effects of ambient air pollution: an update.
abstract: There is new evidence for ambient air pollution (AAP) leading to an increased incidence of respiratory diseases in adults. Research has demonstrated that co-exposures have the potential to dramatically augment the effects of AAP and lower the threshold of effect of a given pollutant. Interactions between genes related to oxidative stress and AAP seem to significantly alter the effect of AAP on an individual and population basis. A better definition of vulnerable populations may bolster local or regional efforts to remediate AAP. Advances in genetic research tools have the potential to identify candidate genes that can guide further research.
authors.affiliation: Air Pollution Exposure Laboratory, Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver General Hospital (VGH)-Research Pavilion, Canada.
authors.forename: Francesco
authors.initials: F
authors.lastname: Sava
authors.forename: Chris
authors.initials: C
authors.lastname: Carlsten
mesh_terms: D000397:Air Pollution / Q000009:adverse effects*; D059647:Gene-Environment Interaction; D006801:Humans; D015994:Incidence; D052638:Particulate Matter / Q000009:adverse effects*; D012140:Respiratory Tract Diseases / Q000453:epidemiology / Q000209:etiology; D018570:Risk Assessment
chemical_list: D052638:Particulate Matter