title: Spectrum of Fuchs uveitic syndrome in a North Indian population.
abstract: OBJECTIVE
  To describe patients with Fuchs uveitis syndrome (FUS) in North India.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  One hundred ninety-eight eyes of 183 patients with FUS were reviewed at the Post Graduate Institute of Medical Education and Research, Advanced Eye Centre, Department of Ophthalmology, between December 1996 and September 2011. Demographic profile, clinical findings at presentation, risk of new complications, and rate of decreased vision were the main outcome measures.
  
  
  RESULTS
  The mean age at presentation was 30.1 ± 9.4 years. Male-to-female ratio was 1.1:1. Fifteen patients (8.1%) had bilateral involvement. Clinical findings at presentation included diffuse keratic precipitates (92.4%), anterior chamber cells (54.5%), diffuse iris atrophy without hypochromia (29.3%), heterochromia (24.7%), iris nodules (16.1%), cataract/pseudophakia (79.3%), vitreous cells (61.1%), elevated intraocular pressure (13.6%), and chorioretinal scars (2%). On fluorescein angiography, hyperfluorescence of the optic disc was detected in 28 of 51 eyes (55%), peripheral vasculitis in 1 (2%) and both in 8 eyes (15.7%). OCT showed traction papillopathy in 6 of 34 eyes (17.6%). None of the eyes showed cystoid macular edema.
  
  
  CONCLUSIONS
  Heterochromia is seen only in 25% of patients with Fuchsheterochromic uveitis in brown irides. Diffuse stellate keratic precipitates, low cellular reaction, vitritis, vitreous opacities, diffuse iris stromal atrophy in the absence of posterior synechia, and macular edema are other parameters helpful in diagnosing FUS.
authors.affiliation: Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Manjari
authors.initials: M
authors.lastname: Tandon
authors.forename: Paavan Puneet
authors.initials: PP
authors.lastname: Malhotra
authors.forename: Vishali
authors.initials: V
authors.lastname: Gupta
authors.forename: Amod
authors.initials: A
authors.lastname: Gupta
authors.forename: Aman
authors.initials: A
authors.lastname: Sharma
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D003941:Diagnostic Techniques, Ophthalmological; D018450:Disease Progression; D005260:Female; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D015863:Iridocyclitis / Q000175:diagnosis* / Q000453:epidemiology; D008297:Male; D012189:Retrospective Studies; D013577:Syndrome; D014792:Visual Acuity