title: Anterior and anterolateral resection for skull base malignancies: techniques and complication avoidance.
abstract: Combined anterior cranial base resection is the mainstay of therapy for skull base malignancies. Improvements in surgical techniques and reconstruction have led to a reduction in morbidity and overall better survival rates. Meticulous attention to dural and skull base reconstruction is essential for reducing the major complications, including cerebrospinal fluid leak and pneumocephalus. Complications can be devastating, but timely effective management can limit the severity.
authors.affiliation: Department of Neurosurgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.
authors.forename: Joshua
authors.initials: J
authors.lastname: Marcus
authors.forename: Ilya
authors.initials: I
authors.lastname: Laufer
authors.forename: Babak
authors.initials: B
authors.lastname: Mehrara
authors.forename: Dennis
authors.initials: D
authors.lastname: Kraus
authors.forename: Bhuvanesh
authors.initials: B
authors.lastname: Singh
authors.forename: Mark H
authors.initials: MH
authors.lastname: Bilsky
mesh_terms: D001706:Biopsy; D065634:Cerebrospinal Fluid Leak; D002559:Cerebrospinal Fluid Rhinorrhea / Q000517:prevention & control; D004388:Dura Mater / Q000601:surgery; D005145:Face / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D019635:Neurosurgical Procedures / Q000009:adverse effects / Q000379:methods*; D011007:Pneumocephalus / Q000517:prevention & control; D011183:Postoperative Complications / Q000517:prevention & control; D019291:Skull Base / Q000601:surgery; D019292:Skull Base Neoplasms / Q000601:surgery*; D013530:Surgical Wound Infection / Q000517:prevention & control; D014057:Tomography, X-Ray Computed