title: Secretion, delivery and function of oomycete effector proteins.
abstract: Oomycetes are responsible for multi-billion dollar damages in aquaculture, agriculture and forestry. One common strategy they share with most cellular disease agents is the secretion of effector proteins. Effectors are molecules that change host physiology by initiating and allowing an infection to develop. Oomycetes secrete both extracellular and intracellular effectors. Studying secretion, delivery and function of effectors will hopefully lead to alternative control measures, which is much needed as several chemicals to control plant and animal pathogenic oomycetes cannot be used anymore; due to resistance in the host, or because the control measures have been prohibited as a result of toxicity to the environment and/or consumers. Here the latest findings on oomycete effector secretion, delivery and function are discussed.
authors.affiliation: Aberdeen Oomycete Laboratory, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK. s.wawra@abdn.ac.uk
authors.forename: Stephan
authors.initials: S
authors.lastname: Wawra
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Belmonte
authors.forename: Lars
authors.initials: L
authors.lastname: Löbach
authors.forename: Marcia
authors.initials: M
authors.lastname: Saraiva
authors.forename: Ariane
authors.initials: A
authors.lastname: Willems
authors.forename: Pieter
authors.initials: P
authors.lastname: van West
mesh_terms: D000818:Animals; D007239:Infections / Q000382:microbiology; D009868:Oomycetes / Q000378:metabolism*; D010935:Plant Diseases / Q000382:microbiology; D010944:Plants; D021381:Protein Transport; D011506:Proteins / Q000378:metabolism*; D037521:Virulence Factors / Q000378:metabolism*
chemical_list: D011506:Proteins; D037521:Virulence Factors