title: Life-threatening ACE inhibitor-induced angioedema after eleven years on lisinopril.
abstract: Angiotensin-converting enzyme inhibitors (ACE-Is) are the primary medication class implicated in drug-associated angioedema. Angioedema is most common early in ACE-I therapy, yet episodes can occur late in therapy and have been reported even as late as 10 years after single treatment initiation. We present a case of a 65-year-old African American woman who experienced 2 episodes of angioedema, with the second being life threatening after receiving several concomitant agents known to cause angioedema, most notably lisinopril for 11 years.
authors.affiliation: Le Bonheur Children's Hospital, Memphis, TN, USA.
authors.forename: Johanna L
authors.initials: JL
authors.lastname: Norman
authors.forename: Whitney L
authors.initials: WL
authors.lastname: Holmes
authors.forename: William A
authors.initials: WA
authors.lastname: Bell
authors.forename: Shannon W
authors.initials: SW
authors.lastname: Finks
mesh_terms: D000368:Aged; D000799:Angioedema / Q000139:chemically induced*; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D005260:Female; D006801:Humans; D017706:Lisinopril / Q000009:adverse effects*
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D017706:Lisinopril