title: Ion recombination correction factors (P(ion)) for Varian TrueBeam high-dose-rate therapy beams.
abstract: Ion recombination is approximately corrected for in the Task Group 51 protocol by Pion, which is calculated by a two-voltage measurement. This measurement approach may be a poor estimate of the true recombination, particularly if Pion is large (greater than 1.05). Concern exists that Pion in high-dose-per-pulse beams, such as flattening filter free (FFF) beams, may be unacceptably high, rendering the two-voltage measurement technique inappropriate. Therefore, Pion was measured for flattened beams of 6, 10, 15, and 18 MV and for FFF beams of 6 and 10 MV. The values for the FFF beams were verified with 1/V versus 1/Q curves (Jaffé plots). Pion was also measured for electron beams of 6, 12, 16, 18, and 20 MeV on a traditional accelerator, as well as on the high-dose-rate Varian TrueBeam accelerator. The measurements were made at a range of depths and with PTW, NEL, and Exradin Farmer-type chambers. Consistent with the increased dose per pulse, Pion was higher for FFF beams than for flattening filter beams. However, for all beams, measurement locations, and chambers examined, Pion never exceeded 1.018. Additionally, Pion was always within 0.3% of the recombination calculated from the Jaffé plots. We conclude that ion recombination can be adequately accounted for in high-dose-rate FFF beams using Pion determined with the standard two-voltage technique.
authors.affiliation: Department of Radiation Physics, Radiological Physics Center, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA. sfkry@mdanderson.org
authors.forename: Stephen F
authors.initials: SF
authors.lastname: Kry
authors.forename: Richard
authors.initials: R
authors.lastname: Popple
authors.forename: Andrea
authors.initials: A
authors.lastname: Molineu
authors.forename: David S
authors.initials: DS
authors.lastname: Followill
mesh_terms: D006801:Humans; D010315:Particle Accelerators / Q000295:instrumentation*; D019047:Phantoms, Imaging; D017785:Photons; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted