title: [How ApoE regulates blood-brain barrier integrity].
authors.forename: Fabien
authors.initials: F
authors.lastname: Gosselet
mesh_terms: D017668:Age of Onset; D000544:Alzheimer Disease / Q000188:drug therapy / Q000453:epidemiology / Q000235:genetics / Q000378:metabolism / Q000503:physiopathology; D016564:Amyloid beta-Protein Precursor / Q000378:metabolism; D000818:Animals; D053327:Apolipoprotein E4 / Q000235:genetics / Q000502:physiology; D001057:Apolipoproteins E / Q000235:genetics / Q000502:physiology*; D001485:Basement Membrane / Q000378:metabolism; D001812:Blood-Brain Barrier / Q000502:physiology*; D002784:Cholesterol / Q000378:metabolism; D021984:Cyclophilin A / Q000378:metabolism; D004790:Enzyme Induction; D006801:Humans; D026503:Low Density Lipoprotein Receptor-Related Protein-1 / Q000378:metabolism; D020935:MAP Kinase Signaling System; D020780:Matrix Metalloproteinase 9 / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology; D008563:Membrane Lipids / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D051379:Mice; D008822:Mice, Transgenic; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000502:physiology*; D020286:Pericytes / Q000378:metabolism; D020033:Protein Isoforms / Q000502:physiology; D013379:Substrate Specificity
chemical_list: D016564:Amyloid beta-Protein Precursor; D053327:Apolipoprotein E4; D001057:Apolipoproteins E; C475476:LRP1 protein, human; D026503:Low Density Lipoprotein Receptor-Related Protein-1; D008563:Membrane Lipids; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; D020033:Protein Isoforms; D002784:Cholesterol; D020780:Matrix Metalloproteinase 9; D021984:Cyclophilin A