title: [Quantitative evaluation of the degrees of traditional Chinese medicine qualitative syndromes of osteoporosis].
abstract: OBJECTIVE
  To establish a quantitative estimate model for diagnosing traditional Chinese medicine (TCM) syndromes of patients with osteoporosis.
  
  
  METHODS
  Symptoms and signs of osteoporosis and methodology related to syndrome research were collected by reviewing medical literature. The symptoms and sighs were quantitatively classified into three, two or one category according to a 100-mm visual analog scale. Fuzzy comprehensive evaluation model of TCM qualitative syndromes was performed based on analytic hierarchy process. Then "Hall for Workshop of Metasynthetic Engineering" expert symposium was held on subjects of syndrome quantification method and weight of evaluation indices in different levels for developing the analysis model of common syndromes. For clinical verification, the created models were applied to patients with osteoporosis for discriminating syndromes. Syndrome of each patient was also identified by 8 experts major in integrative medicine treating osteoporosis for comparing the coincidence rate using a self-made clinical questionnaire.
  
  
  RESULTS
  Through literature reviewing, symptoms and signs quantification and expert discussing, the authors formed estimate models of essence deficit, qi deficiency, yin deficiency, yang deficiency, and blood stasis. A total of 220 patients with osteoporosis were enrolled and filled the clinical questionnaire. All 8 experts completed and returned the questionnaire (1 760 cases), and 1 545 of them were filled in completely. Experts' opinion on syndrome differentiation was exactly coincidence to estimate model in 611 cases and almost coincidence in 639 cases. The total coincidence rate reached to 94.05%.
  
  
  CONCLUSIONS
  The estimate model for syndrome differentiation of osteoporosis has a high-coincidence rate with the fuzzy evaluation from experts, with good rationality and feasibility, and is worthy of promotion in the clinical study.
authors.affiliation: Department of Comprehensive Traditional Chinese Medicine, Qingdao First Sanatorium, Jinan Military Region, Qingdao, Shandong Province, China. lidongtao12345@126.com
authors.forename: Dong-tao
authors.initials: DT
authors.lastname: Li
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Hong-yang
authors.initials: HY
authors.lastname: Jiang
authors.forename: Feng-lei
authors.initials: FL
authors.lastname: Shi
authors.forename: Fu-yu
authors.initials: FY
authors.lastname: Li
authors.forename: Ji-hong
authors.initials: JH
authors.lastname: Liu
authors.forename: Yong-mei
authors.initials: YM
authors.lastname: Cheng
authors.forename: Nan
authors.initials: N
authors.lastname: Yan
authors.forename: Ai-hua
authors.initials: AH
authors.lastname: Hu
authors.forename: Mei-zeng
authors.initials: MZ
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.forename: Ling-bo
authors.initials: LB
authors.lastname: Wei
authors.forename: Rong-qin
authors.initials: RQ
authors.lastname: Jiang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods*; D008875:Middle Aged; D010024:Osteoporosis / Q000175:diagnosis*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D016711:Yang Deficiency; D016710:Yin Deficiency