title: Prevalence and clinical profile of resistant hypertension among treated hypertensive subjects.
abstract: We assessed prevalence and clinical characteristics of resistant hypertension (RH) and prevalence of false RH (white-coat effect [WCE] by home blood pressure [BP] monitoring), among a population of 302 treated hypertensive patients, mean age 66.6 (± 13.8), 67.5% women. Resistant hypertension was defined according to the American Heart Association criteria. Prevalence of RH was 10%, and the following five variables were independently associated with it: body mass index, diabetes, isolated systolic hypertension, orthostatic hypotension, and use of beta-blockers. Prevalence of WCE among subjects with office-RH was 27.6%. Our study identified easily measurable parameters related to RH. Standing BP should be systematically measured in individuals with RH.
authors.affiliation: Hypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires , Buenos Aires , Argentina.
authors.forename: Jessica
authors.initials: J
authors.lastname: Barochiner
authors.forename: José
authors.initials: J
authors.lastname: Alfie
authors.forename: Lucas S
authors.initials: LS
authors.lastname: Aparicio
authors.forename: Paula E
authors.initials: PE
authors.lastname: Cuffaro
authors.forename: Marcelo A
authors.initials: MA
authors.lastname: Rada
authors.forename: Margarita S
authors.initials: MS
authors.lastname: Morales
authors.forename: Carlos R
authors.initials: CR
authors.lastname: Galarza
authors.forename: Gabriel D
authors.initials: GD
authors.lastname: Waisman
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001118:Argentina / Q000453:epidemiology; D001794:Blood Pressure / Q000187:drug effects; D018660:Blood Pressure Monitoring, Ambulatory; D003430:Cross-Sectional Studies; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000453:epidemiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D059466:White Coat Hypertension / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology
chemical_list: D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents