title: Comparative effectiveness research: drug-drug comparisons in heart failure.
abstract: Drug-drug CER is valuable when applied to the right question using the right methods in a relevant context. Being aware of limitations and strengths, and incorporating these insights into the interpretation of results is crucial. Rigorously performed drug-drug CER can help guide clinical practice and future research in HF.
authors.affiliation: Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27705, USA. emil.fosbol@duke.edu
authors.forename: Emil L
authors.initials: EL
authors.lastname: Fosbol
mesh_terms: D002317:Cardiovascular Agents / Q000494:pharmacology / Q000592:standards; D002985:Clinical Protocols; D004346:Drug Information Services; D016903:Drug Monitoring / Q000379:methods / Q000706:statistics & numerical data; D006333:Heart Failure / Q000188:drug therapy / Q000191:economics / Q000453:epidemiology; D006801:Humans; D054539:Medication Therapy Management / Q000592:standards / Q000706:statistics & numerical data; D011358:Product Surveillance, Postmarketing; D016032:Randomized Controlled Trials as Topic; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D002317:Cardiovascular Agents