title: [Efficacy evaluation of laparoscopic gastric bypass for the treatment of obese type 2 diabetes mellitus].
abstract: OBJECTIVE
  To explore the treatment outcomes of obese type 2 diabetes mellitus (T2DM) after laparoscopic gastric bypass.
  
  
  METHODS
  The clinical data of 18 patients with obese T2DM who underwent laparoscopic Roux-en-Y gastric bypass in Beijing Shijitan Hospital between March 2009 and February 2011 were retrospectively analyzed. The clinical parameters included preoperative and postoperative blood glucose, blood lipid, nutrition status and weight lose.
  
  
  RESULTS
  Eighteen patients included 8 men and 10 women. The range of age was 27-62 years (mean, 42.4±10.7 years). The range of BMI was 28.7-57.4 kg/m(2)(mean, 34.9±6.9 kg/m(2)). All the patients underwent laparoscopic Roux-en-Y gastric bypass, and no mortality, complication or conversion to open operation occurred. At 3 months after operation, there were significant changes in OGTT, BMI, HbA1c, Homa-IR and Homa-β(all P<0.05). Fourteen patients(77.8%) showed clinical complete remission, and the overall effective rate was 100%(18/18). The level of blood lipid decreased significantly (P<0.05), and the change of nutritional status was not statistically significant(P>0.05).
  
  
  CONCLUSIONS
  Gastric bypass is an effective treatment for obese type 2 diabetes mellitus.
authors.affiliation: Surgery Centre of Diabetes Mellitus, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
authors.forename: Dong-bo
authors.initials: DB
authors.lastname: Lian
authors.forename: Bu-he
authors.initials: BH
authors.lastname: Amin
authors.forename: Bin
authors.initials: B
authors.lastname: Zhu
authors.forename: Ke
authors.initials: K
authors.lastname: Gong
authors.forename: Kai
authors.initials: K
authors.lastname: Li
authors.forename: Tong-sheng
authors.initials: TS
authors.lastname: Wang
authors.forename: Dong-dong
authors.initials: DD
authors.lastname: Zhang
authors.forename: Neng-wei
authors.initials: NW
authors.lastname: Zhang
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000601:surgery*; D005260:Female; D015390:Gastric Bypass / Q000379:methods*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome