title: [Population-based study of tear production in healthy individuals and patients with dry eye syndrome in Altai Republic].
abstract: For the first time population-based study of tear production was performed, prevalence and risk factors of dry eye syndrome (DES) were determined in native ethnic group of Altai Republic--tubalars. Authors examined 673 people, representing 44% of the whole tubalar population. The mean total tear production (Shirmer test I) was 13,3 +/- 0,3 mm in healthy (without DES signs) tubalars. It ranges in 22,6% of healthy tubalars from 0 to 5 mm, in 20,8%--6 to 11 mm, in 20,5%--12 to 17 mm, in 34,5%-- > 17 mm. Prevalence of DES in tubalar population is 86,18 per thousand. Total tear production (Shirmer test I) in tubalars with DES ranges from 0 to 5 mm in 34%, 6-11 mm in 31,5%, 12-17 mm in 21% and > 17 mm in 13% of eyes. This results showed Shirmer test I to be nonspecific in diagnosis of DES. In author's opinion this test may be useful for follow-up and for assessment of treatment efficacy.
authors.forename: A L
authors.initials: AL
authors.lastname: Onishchenko
authors.forename: A V
authors.initials: AV
authors.lastname: Kolbasko
authors.forename: M A
authors.initials: MA
authors.lastname: Shirina
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D003941:Diagnostic Techniques, Ophthalmological; D015352:Dry Eye Syndromes / Q000175:diagnosis / Q000208:ethnology / Q000503:physiopathology; D005260:Female; D006801:Humans; D007765:Lacrimal Apparatus / Q000378:metabolism / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D044382:Population Groups; D015995:Prevalence; D012307:Risk Factors; D012800:Siberia / Q000453:epidemiology; D013666:Tears / Q000378:metabolism*