title: Management of cervical cancer detected during pregnancy: role of magnetic resonance imaging.
abstract: OBJECTIVE
  The aims of the present study were to assess the role of magnetic resonance imaging (MRI) in the staging and follow-up of uterine cervical cancers discovered during pregnancy and to evaluate the role of MRI in decision making regarding treatment options for patients with uterine cervical cancer during pregnancy.
  
  
  METHODS
  Twelve pregnant women with cervical cancer were included. Two populations of patients were distinguished: localized cervical cancer discovered on the Pap smear during the first trimester of pregnancy, at an early stage (n=5), and invasive cervical cancer revealed later, during the second or third trimester (n=7). Abdominal and pelvic MRI sequences were acquired with a phased-array coil. Magnetic resonance results were correlated with the physical examination, Pap smear, and pathology.
  
  
  RESULTS
  In the first population, MRI was normal or detected a small lesion (stage IB1), and pregnancies were allowed to continue. In the second population, MRI detected a lesion in every case (mean size, 62 mm; 30-110 mm), and positive lymph nodes were depicted in 2 cases. The pregnancy was interrupted in four patients: one interruption in localized cervical cancer group and three in invasive cervical group). In all other cases, a cesarean section was done after the 30th week. In one case, MRI assessed response after chemotherapy administered during pregnancy.
  
  
  CONCLUSIONS
  MRI is an essential examination for planning the treatment of cervical cancers diagnosed during pregnancy.
authors.affiliation: Department of Radiology, Institut Gustave Roussy, Villejuif, France. balleyguier@igr.fr
authors.forename: Corinne
authors.initials: C
authors.lastname: Balleyguier
authors.forename: Claire
authors.initials: C
authors.lastname: Fournet
authors.forename: Wagih
authors.initials: W
authors.lastname: Ben Hassen
authors.forename: Elise
authors.initials: E
authors.lastname: Zareski
authors.forename: Philippe
authors.initials: P
authors.lastname: Morice
authors.forename: Christine
authors.initials: C
authors.lastname: Haie-Meder
authors.forename: Catherine
authors.initials: C
authors.lastname: Uzan
authors.forename: Sébastien
authors.initials: S
authors.lastname: Gouy
authors.forename: Pierre
authors.initials: P
authors.lastname: Duvillard
authors.forename: Catherine
authors.initials: C
authors.lastname: Lhommé
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000628:therapy*; D011379:Prognosis; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D055815:Young Adult