title: Outcome of match related allogeneic stem cell transplantation procedures performed from 2004 till 2011.
abstract: We present our initial experience of allogeneic stem cell transplant procedure performed between April 2004 and August 2011 for various haematological disorders. All patients with non-malignant and malignant haematological disorders with HLA matched donors were selected after pre-transplant workup. Ninety seven patients underwent the procedure. Most common indications for transplant were aplastic anaemia in n = 34 (35%), followed by β-Thalassemia major in n = 21 (21.6%) and chronic myeloid leukemia in n = 11 patients (11.3%). Primary graft failure present was present in 2.06%. Incidence of graft versus host disease (GvHD) in our patients was 34%. After median follow-up of five years the overall survival was 71.3% with a mean survival time of 51.2 ± 3.3 months.
authors.affiliation: FCPS Haematology, Department of Pathology and Microbiology, The Aga Khan University and Hospital, Karachi, Pakistan. natasha.ali@aku.edu.
authors.forename: Natasha
authors.initials: N
authors.lastname: Ali
authors.forename: Salman Naseem
authors.initials: SN
authors.lastname: Adil
authors.forename: Mohammad Usman
authors.initials: MU
authors.lastname: Shaikh
authors.forename: Munira
authors.initials: M
authors.lastname: Moosajee
authors.forename: Nehal
authors.initials: N
authors.lastname: Masood