title: Thirty-minute total synthesis of microfluidic systems and functionalized porous elements via "living" radical photo-polymerization.
abstract: A "living" radical photo-polymerization (LRPP) technique is used to rapidly fabricate microfluidic channels and micro-patterned porous polymer monoliths. Surface-initiated LRPP is then used to functionalize porous elements in a robust one-step surface modification process. Assay-ready platforms can be fully realized in less than 30 minutes. An application relevant to clinical diagnostics is presented.
authors.affiliation: Sandia National Laboratories, Department of Biotechnology & Bioengineering, Livermore, CA 94551, USA.
authors.forename: Vinay V
authors.initials: VV
authors.lastname: Abhyankar
authors.forename: Anson V
authors.initials: AV
authors.lastname: Hatch
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D008027:Light; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation*; D054802:Molecular Imprinting / Q000379:methods*; D049329:Nanostructures / Q000737:chemistry* / Q000528:radiation effects* / Q000648:ultrastructure; D010777:Photochemistry / Q000379:methods*; D011108:Polymers / Q000737:chemistry* / Q000528:radiation effects; D016062:Porosity / Q000528:radiation effects
chemical_list: D011108:Polymers