title: Stealth rare earth oxide nanodiscs for magnetic resonance imaging.
abstract: Configuring RE(2) O(3)  nanocrystals with pseudo-2D morphologies confers substantive gains in relaxivities over equivalent spherical counterparts. The most promising arises from Gd(2) O(3)  whose ionic transverse and longitudinal relaxivities were as high as r(1)  = 12.7 mM(-1)  s(-1)  and r(2)  = 17.2 mM(-1)  s(-1)  (dispersed in H(2) O, T = 37 °C & B(0)  = 1.41 T), pointing to new opportunities to achieve high contrast MRI while concomitantly affording longer half-life potential in vivo.
authors.affiliation: The Molecular Foundry, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Bailey
authors.forename: Rob
authors.initials: R
authors.lastname: van der Weegen
authors.forename: Piper J
authors.initials: PJ
authors.lastname: Klemm
authors.forename: Suzanne L
authors.initials: SL
authors.lastname: Baker
authors.forename: Brett A
authors.initials: BA
authors.lastname: Helms
mesh_terms: D003287:Contrast Media / Q000737:chemistry; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D053758:Nanoparticles / Q000648:ultrastructure; D010316:Particle Size; D012211:Rhenium / Q000737:chemistry
chemical_list: D003287:Contrast Media; C015428:perrhenate; D012211:Rhenium