title: Measurement of ocular anterior segment dimension and wavefront aberration simultaneously during accommodation.
abstract: In order to understand the relationship between accommodation and vision quality, a custom-built ultra-long scan depth spectral domain optical coherence tomography (UL-SDOCT) and a Shack-Hartmann wavefront sensor (HSWFS) were combined. The resolution and scan depth of UL-SDOCT are 6 μm and 15.6 mm, respectively, which allow for high-resolution imaging of the whole anterior segment. The HSWFS consists of a 32 × 32 microlens array, and is able to measure first 35th-order Zernike aberrations with (1/20)λ measurement accuracy. The integrated system succeeded in measuring the ocular anterior segment dimension parameters and the ocular monochromatic high-order aberrations simultaneously under the conditions of nonaccommodative and accommodative stimuli. This may help understand the regulatory mechanism of image quality control in the human eye.
authors.forename: Guohua
authors.initials: G
authors.lastname: Shi
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Wang
authors.forename: Yimin
authors.initials: Y
authors.lastname: Yuan
authors.forename: Lin
authors.initials: L
authors.lastname: Wei
authors.forename: Fan
authors.initials: F
authors.lastname: Lv
authors.forename: Yudong
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000065:Accommodation, Ocular; D000869:Anterior Eye Segment / Q000503:physiopathology*; D019781:Corneal Topography / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D012030:Refractive Errors / Q000175:diagnosis* / Q000503:physiopathology*; D041623:Tomography, Optical Coherence / Q000295:instrumentation*