title: Extending the utility of [Pd(NHC)(cinnamyl)Cl] precatalysts: Direct arylation of heterocycles.
abstract: The use of [Pd(NHC)(cinnamyl)Cl] precatalysts in the direct arylation of heterocycles has been investigated. Among four different precatalysts, [Pd(SIPr)(cinnamyl)Cl] proved to be the most efficient promoter of the reaction. The C-H functionalization of sulfur- or nitrogen-containing heterocycles has been achieved at low catalyst loadings. These catalyst charges range from 0.1 to 0.01 mol % palladium.
authors.affiliation: EaStCHEM School of Chemistry, University of St Andrews, North Haugh, St Andrews, KY16 9ST, UK.
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Martin
authors.forename: Anthony
authors.initials: A
authors.lastname: Chartoire
authors.forename: Alexandra M Z
authors.initials: AM
authors.lastname: Slawin
authors.forename: Steven P
authors.initials: SP
authors.lastname: Nolan