title: Double integration band of HTLV-1 in a young patient with infective dermatitis who developed an acute form of adult T-cell leukemia/lymphoma.
abstract: Few cases of acute adult T-cell leukemia/lymphoma (ATL) have been diagnosed in young patients. This report is the first to describe a young girl with infective dermatitis associated with HTLV-1 that progressed to acute ATL with Southern blot hybridization and gamma-TCR-rearrangement revealing a monoclonal pattern with two copies of the provirus.
authors.affiliation: Service of Dermatology, Complexo Hospitalar Universitário Prof. Edgard Santos, Federal University of Bahia, Rua Dr. Augusto Viana, s/n, Canela, CEP: 40.110-060, Salvador, Bahia, Brazil.
authors.forename: Pedro D
authors.initials: PD
authors.lastname: Oliveira
authors.forename: Marcelo
authors.initials: M
authors.lastname: Magalhães
authors.forename: Juliana M
authors.initials: JM
authors.lastname: Argolo
authors.forename: Achiléa L
authors.initials: AL
authors.lastname: Bittencourt
authors.forename: Lourdes
authors.initials: L
authors.lastname: Farre
mesh_terms: D000293:Adolescent; D015139:Blotting, Southern; D003872:Dermatitis / Q000150:complications / Q000473:pathology* / Q000821:virology*; D005260:Female; D015321:Gene Rearrangement; D019675:Genes, T-Cell Receptor gamma; D015368:Human T-lymphotropic virus 1 / Q000235:genetics* / Q000472:pathogenicity*; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000150:complications / Q000473:pathology* / Q000821:virology*; D011533:Proviruses / Q000235:genetics; D016662:Virus Integration; D055815:Young Adult