title: Depression and life quality in chronic renal failure patients with polyneuropathy on hemodialysis.
abstract: OBJECTIVE
  To investigate the relationship between severity of peripheral polyneuropathy (PPN) and degree of depression and quality of life in chronic renal failure (CRF) patients on hemodialysis (HD).
  
  
  METHODS
  Forty seven chronic renal failure patients on hemodialysis were recruited (22 male, 25 female, mean age of 63.17±12.52) and etiology, disease duration, hemodialysis duration, creatinine and hemoglobin were recorded. Motor and sensory nerve conduction studies were carried out on bilateral median, ulnar, tibial and peroneal nerves for diagnosis of polyneuropathy according to our laboratory criteria. The Korean version of Beck depression inventory (BDI) questionnaire translated into Korean for diagnosis of depression, and Korean version of Short Form 36 health survey (SF-36) questionnaire for measurement of general health level were measured in those diagnosed with uremic PPN.
  
  
  RESULTS
  Out of 52 patients, 47 were diagnosed with polyneuropathy and mean score for BDI was 18.49±9.18. Mean scores for each of Mental Component Summary (MCS) and Physical Component Summary (PCS) of SF-36 were 50.84±15.42 and 47.41±18.68. The correlation between the scores and polyneuropathy were analyzed by Pearson coefficient. The MCS score was the significant (p<0.05) correlation parameter with depression (R=-0.635) and the PCS score was the only parameter with a significant (p<0.05) correlation with polyneuropathy (R=-0.340).
  
  
  CONCLUSIONS
  Uremic polyneuropathy is commonly observed in chronic renal failure patients on hemodialysis. Depression in CRF with uremic PPN is affected by psychological factors other than the PPN itself.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 630-522, Korea.
authors.forename: Do Yub
authors.initials: do Y
authors.lastname: Ku
authors.forename: Young Sook
authors.initials: YS
authors.lastname: Park
authors.forename: Hyun Jung
authors.initials: HJ
authors.lastname: Chang
authors.forename: Sung Rok
authors.initials: SR
authors.lastname: Kim
authors.forename: Jeoung Whan
authors.initials: JW
authors.lastname: Ryu
authors.forename: Woo Jin
authors.initials: WJ
authors.lastname: Kim