title: Fatigue in immune-mediated neuropathies.
abstract: Fatigue, a highly debilitating symptom, is reported in most patients with immune-mediated neuropathies, particularly in Guillain-Barré syndrome, chronic immune-mediated demyelinating polyradiculoneuropathy, monoclonal gammopathy of undetermined significance related polyneuropathy, and multifocal motor neuropathy. Aspects like the degree of known fatigue in these disorders, its impact on daily functioning and quality of life, the suggested underlying mechanisms, and possible therapeutic interventions for fatigue will be addressed in this review.
authors.affiliation: Department of Neurology, Spaarne Hospital, Hoofddorp, The Netherlands. isjmerkies@planet.nl
authors.forename: Ingemar S J
authors.initials: IS
authors.lastname: Merkies
authors.forename: Catharina G
authors.initials: CG
authors.lastname: Faber
mesh_terms: D002908:Chronic Disease; D003711:Demyelinating Diseases / Q000175:diagnosis / Q000276:immunology*; D020275:Guillain-Barre Syndrome / Q000175:diagnosis / Q000276:immunology*; D006801:Humans; D018763:Muscle Fatigue / Q000502:physiology*; D011129:Polyradiculoneuropathy / Q000175:diagnosis / Q000276:immunology*; D011788:Quality of Life