title: Jekyll and Hide:  The two faces of amyloid β.
abstract: Neurodegenerative diseases are a burden of our century. Although significant efforts were made to find a cure or relief to this scourge, their pathophysiology remains vague and the cellular function of the key involved proteins is still unclear. However, in the case of amyloid β (Aβ), a key protein concerned in Alzheimer disease, we are now a step closer in the unscrambling of its cellular functions. Interestingly, whereas the exact role of Aβ in the pathophysiology of Alzheimer disease is still unresolved, a recent study revealed a neuroprotective function of Aβ in multiple sclerosis with possibly promising therapeutic benefits.
authors.affiliation: Hotchkiss Brain Institute; Department of Clinical Neuroscience; Calgary, AB Canada.
authors.forename: Juliane
authors.initials: J
authors.lastname: Proft
authors.forename: Norbert
authors.initials: N
authors.lastname: Weiss