title: Diffusion-weighted imaging of patients with neonatal bilirubin encephalopathy.
abstract: OBJECTIVE
  The aim of the study is to evaluate neonatal bilirubin encephalopathy in the acute period by the DWI.
  
  
  METHODS
  Thirty newborn babies with hyperbilirubinemia at the gestational age of 38-40 weeks, diagnosed with acute neonatal bilirubin encephalopathy as a result of clinical findings were included in the study, and a further 24 newborn babies, whose ages, weights and gestational ages were equalized, were regarded as a control group. DWI was performed on both patient and control groups.
  
  
  RESULTS
  When DWI apparent diffusion coefficients (ADC) of both neonatal bilirubin encephalopathy patients and the control group were compared, ACD values of neonatal bilirubin encephalopathy patients were found to be statistically significantly highly compared to that of the control group (p < 0.001). There was a significant correlation between bilirubin values and DWI findings (r = 0.41, p < 0.05).
  
  
  CONCLUSIONS
  The ADC measurement could be a promising parameter in detecting neonatal bilirubin encephalopathy.
authors.affiliation: Department of Radiology, Harran University Medical Faculty, 63100 Sanliurfa, Turkey. Hasan_cece@yahoo.com
authors.forename: Hasan
authors.initials: H
authors.lastname: Cece
authors.forename: Mahmut
authors.initials: M
authors.lastname: Abuhandan
authors.forename: Alpay
authors.initials: A
authors.lastname: Cakmak
authors.forename: Sema
authors.initials: S
authors.lastname: Yildiz
authors.forename: Mustafa
authors.initials: M
authors.lastname: Calik
authors.forename: Ekrem
authors.initials: E
authors.lastname: Karakas
authors.forename: Omer
authors.initials: O
authors.lastname: Karakas
mesh_terms: D000975:Antioxidants; D001663:Bilirubin / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D001835:Body Weight; D016022:Case-Control Studies; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D015931:Intensive Care, Neonatal; D007647:Kernicterus / Q000097:blood / Q000175:diagnosis*; D008297:Male; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D001663:Bilirubin