title: Gene therapy. Factor IX Padua: them that have, give.
abstract: In this issue of Blood, Finn et al have taken a factor IX variant with increased specific activity associated with thrombophilia and used it to improve gene therapy of hemophilia B in dogs, and Cantore et al have shown similar results in mice.
authors.affiliation: National Institutes of Health Clinical Center.
authors.forename: Jay N
authors.initials: JN
authors.lastname: Lozier
mesh_terms: D000818:Animals; D005164:Factor IX / Q000235:genetics*; D015316:Genetic Therapy / Q000379:methods*; D002836:Hemophilia B / Q000628:therapy*; D006801:Humans; D008297:Male; D009154:Mutation
chemical_list: D005164:Factor IX