title: ABI4: versatile activator and repressor.
abstract: The ABSCISIC ACID INSENSITIVE4 (ABI4) gene was discovered to be an abscisic acid (ABA) signaling responsive transcription factor active during seed germination. The evolutionary history of the ABI4 gene supports its role as an ABA signaling intermediate in land plants. Investigating the ABI4 protein-cis element interaction supports the proposal that ABI4 binding to its known CE1 cis-element competes with transcription factor binding to the overlapping G-Box element. Recent publications report on ABI4 as a regulatory factor in diverse processes. In developing seedlings, ABI4 mediates sugar signaling, lipid breakdown, and plastid-to-nucleus signaling. Moreover, ABI4 is a regulator of rosette growth, redox signaling, cell wall metabolism and the effect of nitrate on lateral root development.
authors.affiliation: Molecular Plant Physiology, Institute of Environmental Biology, Utrecht University, Utrecht, The Netherlands.
authors.forename: Julia J
authors.initials: JJ
authors.lastname: Wind
authors.forename: Alessia
authors.initials: A
authors.lastname: Peviani
authors.forename: Berend
authors.initials: B
authors.lastname: Snel
authors.forename: Johannes
authors.initials: J
authors.lastname: Hanson
authors.forename: Sjef C
authors.initials: SC
authors.lastname: Smeekens
mesh_terms: D000040:Abscisic Acid / Q000378:metabolism*; D002473:Cell Wall / Q000378:metabolism; D019669:Embryophyta / Q000235:genetics* / Q000254:growth & development / Q000502:physiology; D019143:Evolution, Molecular; D018507:Gene Expression Regulation, Developmental; D018506:Gene Expression Regulation, Plant / Q000235:genetics*; D018525:Germination; D050356:Lipid Metabolism; D008055:Lipids; D008958:Models, Molecular; D010084:Oxidation-Reduction; D010802:Phylogeny; D010937:Plant Growth Regulators / Q000378:metabolism; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D018517:Plant Roots / Q000235:genetics / Q000254:growth & development / Q000502:physiology; D017434:Protein Structure, Tertiary; D036226:Seedlings / Q000235:genetics / Q000254:growth & development / Q000502:physiology; D012639:Seeds / Q000235:genetics / Q000254:growth & development / Q000502:physiology; D015398:Signal Transduction; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D008055:Lipids; D010937:Plant Growth Regulators; D010940:Plant Proteins; D014157:Transcription Factors; D000040:Abscisic Acid