title: An argonaute protein directs nuclear Xrn2 function.
abstract: Argonaute proteins are the mediators of small RNA-guided gene silencing pathways. In this issue, Couvillion and coworkers (Couvillion et al., 2012) found an unexpected function for a Tetrahymena Argonaute protein: It forms a complex with tRNA fragments and is required for nuclear Xrn2 localization and function.
authors.affiliation: Biochemistry Center Regensburg (BZR), Laboratory for RNA Biology, University of Regensburg, Universitätsstrasse 31, 93053 Regensburg, Germany.
authors.forename: Daniele
authors.initials: D
authors.lastname: Hasler
authors.forename: Gunter
authors.initials: G
authors.lastname: Meister