title: Divide Et Impera--cellular auxin compartmentalization.
abstract: The phytohormone auxin is an essential regulator for plant growth and development. Decades of intensive research revealed the mutual importance of auxin metabolism and intercellular cell-to-cell transport for the regulation of spatiotemporal auxin distribution. Just recently, intracellular putative auxin carriers, such as the PIN-FORMED (PIN)5/PIN8 and the PIN-LIKES (PILS)2/PILS5 were discovered at the endoplasmic reticulum (ER) and seem to limit nuclear auxin signaling via an auxin sequestration mechanism. Moreover, these auxin carriers at the ER might provide a link between auxin compartmentalization and auxin conjugation-based metabolism. Here we review the recent findings on auxin compartmentalization at the ER and discuss its potential contribution to cellular auxin homeostasis and its importance for plant development.
authors.affiliation: Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences, Vienna (BOKU), 1190 Vienna, Austria.
authors.forename: Elke
authors.initials: E
authors.lastname: Barbez
authors.forename: Jürgen
authors.initials: J
authors.lastname: Kleine-Vehn
mesh_terms: D001692:Biological Transport; D002451:Cell Compartmentation; D004721:Endoplasmic Reticulum / Q000378:metabolism; D006706:Homeostasis; D007210:Indoleacetic Acids / Q000378:metabolism*; D063245:Plant Development; D010937:Plant Growth Regulators / Q000378:metabolism*; D010940:Plant Proteins / Q000378:metabolism*; D010944:Plants / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D007210:Indoleacetic Acids; D010937:Plant Growth Regulators; D010940:Plant Proteins