title: Natural product synthesis: changes over time.
abstract: For almost 200 years, the synthesis of natural products has been practiced. In this time span, not only the target structures have become increasingly more complex, the objectives of natural product synthesis have also changed. Likewise, the standards and criteria for the conduction of natural product synthesis have changed. It is these changes that form the subject of this Essay.
authors.affiliation: Fachbereich Chemie der Philipps Universität, Marburg, Germany. rwho@chemie.uni-marburg.de
authors.forename: Reinhard W
authors.initials: RW
authors.lastname: Hoffmann
mesh_terms: D001688:Biological Products / Q000138:chemical synthesis* / Q000737:chemistry; D060326:Chemistry Techniques, Synthetic / Q000639:trends*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D001688:Biological Products