title: Cognitive Function of Korean Neurosurgical Patients: Cross-sectional Study Using the Korean Version of the Mini-mental Status Examination.
abstract: OBJECTIVE
  As interest in life quality and expectancy increases, cognitive dysfunction is becoming an important topic. Although there are many foreign articles on this topic, they require cultural interpretation to be applicable to Koreans. The purpose of this study was to assess cognitive function in Korean neurosurgical patients.
  
  
  METHODS
  We recruited 214 adult Korean patients with various cerebral pathologies and treatments from an outpatient clinic. The male-to-female ratio was 88:126, and their ages ranged from 28 to 81 years (mean: 57.9 years). The Korean version of the mini-mental status examination (K-MMSE) was adopted as an instrument for measuring cognitive function, and a score ≤23 was defined as cognitive dysfunction. K-MMSE scores were analyzed considering the patients' gender, age, time elapsed since treatments, pathology and treatment modality. A serial analysis was performed for 59 patients who completed the K-MMSE more than once.
  
  
  RESULTS
  The mean K-MMSE score of 214 patients was 22.3, and 133 patients (62.1%) had a score ≤23. Cognitive dysfunction was common regardless of age, gender, pathology or treatment modality. Serial analysis revealed K-MMSE score improvement in 45 of 59 patients (76.3%). The mean time interval between two tests was 11.9 months, and the mean K-MMSE score improvement was 2.7, which was statistically significant (P = 0.000). However, many still had cognitive impairment.
  
  
  CONCLUSIONS
  Most Korean neurosurgical patients showed cognitive dysfunction despite improvement after several months. Patients with trauma or ischemic disease were more vulnerable. More attention should be paid to neuropsychological complications such as cognitive dysfunction.
authors.affiliation: Department of Neurosurgery, Kangwon National University Hospital, Seoul, Korea.
authors.forename: Jiha
authors.initials: J
authors.lastname: Kim
authors.forename: Chi Heon
authors.initials: CH
authors.lastname: Kim
authors.forename: Hyun-Seung
authors.initials: HS
authors.lastname: Kang
authors.forename: Chul-Kee
authors.initials: CK
authors.lastname: Park
authors.forename: Chun Kee
authors.initials: CK
authors.lastname: Chung