title: Radiographic features in a rare case of sphenoid sinus extramedullary hematopoeisis in sickle cell disease.
abstract: Sickle cell disease is a common hematologic disorder with some uncommon clinical manifestations. While there are an abundance of described disease manifestations of the head and neck, extramedullary hematopoesis within the paranasal sinuses is exceedingly rare. Here, we present a case of a young boy with known sickle cell disease who presented to hospital with headaches of new onset. Imaging demonstrated an expansile mass lesion occupying the sphenoid sinus and on biopsy was found to be active hematopoetic bone marrow. A description of the case and review of subtle but characteristic radiographic findings follow.
authors.affiliation: Department of Otolaryngology - Head and Neck Surgery, University of Toronto, 190 Elizabeth St, Toronto, ON M5G 2N2, Canada. michael.sklar@mail.utoronto.ca
authors.forename: Michael
authors.initials: M
authors.lastname: Sklar
authors.forename: Carmen
authors.initials: C
authors.lastname: Rotaru
authors.forename: David
authors.initials: D
authors.lastname: Grynspan
authors.forename: Matthew
authors.initials: M
authors.lastname: Bromwich
mesh_terms: D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D008297:Male; D013101:Sphenoid Sinus / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed