title: A novel ratiometric emission probe for Ca2+ in living cells.
abstract: A ratiometric fluorescent probe for Ca(2+) based on 1,3,4-oxadiazole derivative has been designed and developed. The probe exhibits a large Stokes shift of 202 nm and a highly selective ratiometric emission response (490/582 nm) to Ca(2+) over other metal cations. Additionally, the probe can readily reveal the changes of intracellular Ca(2+) concentration in living human umbilical vein endothelial cells.
authors.affiliation: Research Center of Environmental Science and Engineering, and School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, P. R. China.
authors.forename: Qiaoling
authors.initials: Q
authors.lastname: Liu
authors.forename: Wei
authors.initials: W
authors.lastname: Bian
authors.forename: Heping
authors.initials: H
authors.lastname: Shi
authors.forename: Li
authors.initials: L
authors.lastname: Fan
authors.forename: Shaomin
authors.initials: S
authors.lastname: Shuang
authors.forename: Chuan
authors.initials: C
authors.lastname: Dong
authors.forename: Martin M F
authors.initials: MM
authors.lastname: Choi
mesh_terms: D002118:Calcium / Q000032:analysis*; D002478:Cells, Cultured; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D061307:Human Umbilical Vein Endothelial Cells / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure; D014230:Triazoles / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D014230:Triazoles; D002118:Calcium