title: Follicle flushing in monofollicular in vitro fertilization almost doubles the number of transferable embryos.
abstract: Follicle flushing has been proved to be ineffective in polyfollicular in vitro fertilization. To analyze the effect of flushing in monofollicular in vitro fertilization we aspirated and then flushed the follicles in 164 cycles. Total oocyte yield/aspiration was 44.5% in the aspirate, 20.7% in the 1(st)  flush, 10.4% in the 2(nd)  flush and 4.3% in the 3(rd)  flush. By flushing, the total oocyte yield increased (p < 0.01) by 80.9%, from 44.5 to 80.5%. The total transfer rate increased (p < 0.01) by 91.0%, from 20.1 to 38.4%. The results indicate that the oocyte yield and the number of transferable embryos can be increased significantly by flushing.
authors.affiliation: Department of Gynecological Endocrinology and Reproductive Medicine, University Women's Hospital, Effingerstrasse 102, Bern, Switzerland. michael.vonwolff@insel.ch
authors.forename: Michael
authors.initials: M
authors.lastname: von Wolff
authors.forename: Yu-Zhen
authors.initials: YZ
authors.lastname: Hua
authors.forename: Alessandro
authors.initials: A
authors.lastname: Santi
authors.forename: Erika
authors.initials: E
authors.lastname: Ocon
authors.forename: Benedicte
authors.initials: B
authors.lastname: Weiss
mesh_terms: D000328:Adult; D004624:Embryo Transfer; D005260:Female; D005306:Fertilization; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D054315:Oocyte Retrieval / Q000379:methods*; D009865:Oocytes; D006080:Ovarian Follicle / Q000166:cytology*; D011247:Pregnancy