title: Factor V Leiden and Prothrombin 20210A Mutations among Turkish Pediatric Leukemia Patients.
abstract: This study was undertaken to determine the prevalence of the Factor V 1691 G-A and PT 20210 G-A mutations in Turkish children with leukemia. We genotyped 135 pediatric leukemia patients with for these mutations. Eleven (8%) of the 135 patients were heterozygous for the FV 1691 G-A mutation. Seven (5,1%) of the patients carried the PT 20210 G-A heterozygous mutation. Of the 135 patients, only three had thrombotic event, none of which had these two mutations, which is common in Turkish population. Our findings revealed a controversial compared to the previous reports, which needs further investigation.
authors.affiliation: LOSEV the Foundation for Children with Leukemia, Ankara, Turkey.
authors.forename: Dilara Fatma
authors.initials: DF
authors.lastname: Akın
authors.forename: Kadir
authors.initials: K
authors.lastname: Sipahi
authors.forename: Tuğba
authors.initials: T
authors.lastname: Kayaalp
authors.forename: Yonca
authors.initials: Y
authors.lastname: Eğin
authors.forename: Serpil
authors.initials: S
authors.lastname: Taşdelen
authors.forename: Emin
authors.initials: E
authors.lastname: Kürekçi
authors.forename: Ustün
authors.initials: U
authors.lastname: Ezer
authors.forename: Nejat
authors.initials: N
authors.lastname: Akar