title: Advanced paternal age and vulnerability to psychotic-like experiences in the offspring.
abstract: OBJECTIVE
  To investigate whether advanced paternal age is associated with increased psychotic-like experiences (PLEs) and increased sensitivity to Cannabis in the offspring.
  
  
  METHODS
  A cross-sectional population-based study in 1684 participants aged 18 to 25.
  
  
  RESULTS
  We found no association of paternal age with PLEs. Only the positive dimension subscale was associated to paternal age, but that could be largely contributed to outliers. Also no increased sensitivity to Cannabis smoking was apparent.
  
  
  CONCLUSIONS
  In the general population, we did not find robust support for an association between paternal age and vulnerability to PLEs in 18-25year old offspring.
authors.affiliation: Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Department of Psychiatry, The Netherlands. a.vreeker@umcutrecht.nl
authors.forename: Annabel
authors.initials: A
authors.lastname: Vreeker
authors.forename: Christian D
authors.initials: CD
authors.lastname: Schubart
authors.forename: Willemijn A
authors.initials: WA
authors.lastname: van Gastel
authors.forename: René S
authors.initials: RS
authors.lastname: Kahn
authors.forename: Marco P M
authors.initials: MP
authors.lastname: Boks
mesh_terms: D000293:Adolescent; D000328:Adult; D002188:Cannabis / Q000009:adverse effects; D018672:Community Health Planning; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D010331:Paternal Age; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000453:epidemiology* / Q000235:genetics*; D055815:Young Adult