title: Asymmetric ion-pairing catalysis.
abstract: Charged intermediates and reagents are ubiquitous in organic transformations. The interaction of these ionic species with chiral neutral, anionic, or cationic small molecules has emerged as a powerful strategy for catalytic, enantioselective synthesis. This review describes developments in the burgeoning field of asymmetric ion-pairing catalysis with an emphasis on the insights that have been gleaned into the structural and mechanistic features that contribute to high asymmetric induction.
authors.affiliation: Department of Chemistry and Chemical Biology, Harvard University, Cambridge MA 02138, USA.
authors.forename: Katrien
authors.initials: K
authors.lastname: Brak
authors.forename: Eric N
authors.initials: EN
authors.lastname: Jacobsen
mesh_terms: D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D007477:Ions / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D009930:Organic Chemicals / Q000737:chemistry*; D055601:Organic Chemistry Phenomena; D013237:Stereoisomerism
chemical_list: D007477:Ions; D009930:Organic Chemicals