title: Construction of 3D, layered skin, microsized tissues by using cell beads for cellular function analysis.
abstract: Microsized skin cell beads consisting of 3D layered structures with epidermal and dermal cells have been fabricated. The beads are monodisperse, type-I collagen beads encapsulating dermal cells and covered by epidermal cells. The beads can be used in individual analyses of cellular functions and respond to chemical stimulation.
authors.affiliation: The University of Tokyo, Tokyo, Japan.
authors.forename: Yuya
authors.initials: Y
authors.lastname: Morimoto
authors.forename: Risa
authors.initials: R
authors.lastname: Tanaka
authors.forename: Shoji
authors.initials: S
authors.lastname: Takeuchi
mesh_terms: D002478:Cells, Cultured; D005347:Fibroblasts / Q000166:cytology*; D006801:Humans; D015603:Keratinocytes / Q000166:cytology*; D012867:Skin / Q000166:cytology*; D023822:Tissue Engineering / Q000379:methods*