title: Assessment of oxidant/antioxidant system in newborns and their breast milks.
abstract: OBJECTIVE
  In this study, it is aimed to investigate total oxidant and antioxidant status of newborns and their breast milks.
  
  
  METHODS
  Totally, 184 infants who were born in our hospital were included in the study. Study group was divided into two main study groups, including term and preterm groups; main study groups were also divided into two sub-groups, AGA and SGA. TOS and TAC levels were measured in cord blood of all newborns and in mother milks. Groups were statistically compared with each other in terms of TOS, TAC and OSI levels.
  
  
  RESULTS
  The study included 92 preterm newborns (Group I) and 92 term newborns (Group II). TOS, TAC and OSI levels were found significantly higher in Group I than Group II (p < 0.0001, p = 0.17, p < 0.0001, respectively). When sub-groups of Group I and Group II, namely TAGA, TSGA and PAGA and PSGA, were compared with each other. TOS and OSI levels were significantly higher and TAC levels were significantly lower in TSGA group relative to TAGA group (p < 0.0001; p = 0.001; p < 0.0001, respectively). No statistically significant difference was found between Group I and Group II and between sub-groups of Group I and II with regards the TOC, TAC and OSI levels of mother milk.
  
  
  CONCLUSIONS
  In preterm newborns and term SGA infants, total oxidant stress is increased and antioxidant capacity is low. No significant difference was found between mother milks of preterm and term AGA and SGA infants.
authors.affiliation: Neonatology Department, Zekai Tahir Burak Maternity Teaching Hospital, Altindag, Ankara, Turkey. gonca.sandal@hotmail.com
authors.forename: Gonca
authors.initials: G
authors.lastname: Sandal
authors.forename: Nurdan
authors.initials: N
authors.lastname: Uras
authors.forename: Tulin
authors.initials: T
authors.lastname: Gokmen
authors.forename: Serife Suna
authors.initials: SS
authors.lastname: Oguz
authors.forename: Omer
authors.initials: O
authors.lastname: Erdeve
authors.forename: Ugur
authors.initials: U
authors.lastname: Dilmen
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000032:analysis*; D001724:Birth Weight; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn / Q000097:blood*; D007234:Infant, Premature / Q000097:blood*; D007236:Infant, Small for Gestational Age / Q000097:blood; D008297:Male; D008423:Maternal Age; D008895:Milk, Human / Q000737:chemistry*; D016877:Oxidants / Q000097:blood*; D018384:Oxidative Stress
chemical_list: D000975:Antioxidants; D016877:Oxidants