title: Non-contrast-enhanced magnetic resonance angiography using T2-weighted 3-dimensional fat-suppressed turbo spin echo (SPACE): diagnostic performance and comparison with contrast-enhanced magnetic resonance angiography using volume interpolated breath-hold examination in the detection of portosystemic and portohepatic collaterals.
abstract: OBJECTIVE
  The objective of this study was to evaluate the diagnostic performance of non-contrast-enhanced magnetic resonance angiography (non-CE-MRA) using SPACE ("Sampling Perfection with Application optimized Contrasts using different flip angle Evolutions") in comparison with CE-MRA using volume interpolated breath-hold examination (VIBE) in the detection of portosystemic and portohepatic collaterals.
  
  
  METHODS
  Thirty consecutively enrolled cirrhotic patients with suspicion of portosystemic and portohepatic collaterals underwent SPACE followed by VIBE at 1.5-T magnetic resonance imaging scanner. The contrast-to-noise ratio, signal-to-noise ratio, and scores of the portal vein segments and overall image were used to compare the diagnostic performance of SPACE with that of VIBE. The paired Student t test and the Wilcoxon signed rank test were used for statistical analysis.
  
  
  RESULTS
  Diagnostic results of SPACE were equivalent to those of VIBE. However, both the signal-to-noise ratio and contrast-to-noise ratio of portal vein segments in the former were better than those in the latter (P < 0.0001), and the scores of displaying the portal vein distal branches in SPACE were higher than those in VIBE (P < 0.05).
  
  
  CONCLUSIONS
  The SPACE has a comparable ability in demonstrating portosystemic and portohepatic collaterals as well as VIBE does.
authors.affiliation: Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, People's Republic of China.
authors.forename: Qiong
authors.initials: Q
authors.lastname: Song
authors.forename: Mengsu
authors.initials: M
authors.lastname: Zeng
authors.forename: Caizhong
authors.initials: C
authors.lastname: Chen
authors.forename: Jing
authors.initials: J
authors.lastname: Ma
authors.forename: Hong
authors.initials: H
authors.lastname: Yun
authors.forename: Shengxiang
authors.initials: S
authors.lastname: Rao
authors.forename: Xiuzhong
authors.initials: X
authors.lastname: Yao
mesh_terms: D000328:Adult; D000368:Aged; D062485:Breath Holding; D003097:Collateral Circulation; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008099:Liver / Q000098:blood supply / Q000473:pathology; D008103:Liver Cirrhosis / Q000150:complications*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011169:Portal Vein / Q000002:abnormalities*; D012680:Sensitivity and Specificity; D059629:Signal-To-Noise Ratio; D018709:Statistics, Nonparametric
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA