title: A novel microfluidic approach for monodispersed chitosan microspheres with controllable structures.
abstract: A novel and simple approach to prepare monodispersed chitosan microspheres with relative small size and controlled structures was developed by combining the solidification methods of solvent extraction and chemical crosslinking in a capillary-embedded microfluidic decive. The microspheres with different structures are used in the field of protein drug controlled release and immobilization lipases and they show different release profiles and good stability, respectively.
authors.affiliation: The State Key Lab of Chemical Engineering, Department of Chemical Engineering, Tsinghua University, 100084, Beijing, PR China. xujianhong@tsinghua.edu.cn
authors.forename: Jian-Hong
authors.initials: JH
authors.lastname: Xu
authors.forename: Hong
authors.initials: H
authors.lastname: Zhao
authors.forename: Wen-Jie
authors.initials: WJ
authors.lastname: Lan
authors.forename: Guang-Sheng
authors.initials: GS
authors.lastname: Luo
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis*; D048271:Chitosan / Q000737:chemistry*; D044085:Microfluidics / Q000379:methods*; D008863:Microspheres; D008968:Molecular Conformation; D010316:Particle Size; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials; D048271:Chitosan