title: CTCs hemodialysis: can it be a new therapy for breast cancer?
abstract: Circulating tumor cells (CTCs) play an important role in Blood-borne distant metastasis, which is the leading cause of cancer-related death in breast cancer. So far, the impacts of CTCs as a tool for predicting or monitoring the efficacy of systemic therapy and that it is a independent prognostic factor have been confirmed. However, CTCs cannot be generally removed at primary surgery or by systemic therapy. In some EMT (epithelial mesenchymal transition)-related treatment fail, CTCs can be accumulated in the postoperative course of the patient which lead to a bad prognosis. In view of these, considering mature hemodialysis technology, we further propose CTCs hemodialysis (CHD), which filtrate CTCs out of blood, as a new therapy for the breast cancer.
authors.affiliation: Chinese Academy of Medical Sciences & Peking Union Medical College, Department of Breast Surgery, Peking Union Medical College Hospital, Beijing 100730, China. xuefeibanyi@yahoo.com.cn
authors.forename: Xuefei
authors.initials: X
authors.lastname: Wang
authors.forename: Qiang
authors.initials: Q
authors.lastname: Sun
authors.forename: Feng
authors.initials: F
authors.lastname: Mao
authors.forename: Songjie
authors.initials: S
authors.lastname: Shen
authors.forename: Likun
authors.initials: L
authors.lastname: Huang
mesh_terms: D001943:Breast Neoplasms / Q000628:therapy*; D005260:Female; D006440:Hemofiltration / Q000379:methods*; D006801:Humans; D008954:Models, Biological; D009360:Neoplastic Cells, Circulating