title: Optimizing cine MRI for uterine peristalsis: a comparison of three different single shot fast spin echo techniques.
abstract: OBJECTIVE
  To determine the optimal single shot fast spin echo (SSFSE) technique by varying interval between image acquisitions for cine MRI of uterine peristalsis.
  
  
  METHODS
  MRI was performed in 13 premenopausal women (4 normal and 9 with benign pelvic pathology) in various phases of their menstrual cycle. Midsagittal uterus was scanned using a multiphasic SSFSE technique at 2-, 3-, and 4-s intervals over 2 min. Three readers independently and randomly evaluated for peristaltic frequency/2 min, longitudinal direction and intensity of peristalsis in three imaging parameters. Contrast-to-noise ratios (CNRs) were also obtained.
  
  
  RESULTS
  Peristaltic frequency for the 2, 3, and 4 s was 2.2 ± 2.3, 3.3 ± 1.5, and 3.6 ± 1.3 waves/2 min, respectively. It increased by 1.5 (95% confidence interval [CI]: 0.31-2.64) waves/2 min with 4 s compared with 2 s. Direction was detected for the 2, 3, and 4 s in 5/13(38%), 9/13(69%) and 12/13(92%) women. Compared with 2 s, intensity of peristalsis in endometrial movement (P = 0.04), signal change of the JZ (P = 0.03), and spread into outer myometrium (P = 0.02), CNRendometrium-JZ by 57% (P < 0.001), and CNRouter myometrium-JZ by 45% (P < 0.01) increased with 4 s.
  
  
  CONCLUSIONS
  Cine MRI with SSFSE sequence for uterine peristaltism is best performed using a 4-s scan interval.
authors.affiliation: Diagnostic Radiology, Montreal General Hospital, McGill University Health Center, Montreal, PQ, Canada. asanakai@kuhp.kyoto-u.ac.jp
authors.forename: Asako
authors.initials: A
authors.lastname: Nakai
authors.forename: Caroline
authors.initials: C
authors.lastname: Reinhold
authors.forename: Patricia
authors.initials: P
authors.lastname: Noel
authors.forename: Aki
authors.initials: A
authors.lastname: Kido
authors.forename: Khashayar
authors.initials: K
authors.lastname: Rafatzand
authors.forename: Isao
authors.initials: I
authors.lastname: Ito
authors.forename: Kaori
authors.initials: K
authors.lastname: Togashi
mesh_terms: D000328:Adult; D000465:Algorithms; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008597:Menstrual Cycle / Q000502:physiology*; D015588:Observer Variation; D010528:Peristalsis / Q000502:physiology*; D017697:Premenopause; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013113:Spin Labels; D014599:Uterus / Q000033:anatomy & histology* / Q000502:physiology*
chemical_list: D013113:Spin Labels