title: Photodynamic therapy for skin rejuvenation: review and summary of the literature--results of a consensus conference of an expert group for aesthetic photodynamic therapy.
abstract: Skin rejuvenating effects of photodynamic therapy (PDT) for photoaged skin has been well-documented in several clinical trials. Different photosensitizers (5-aminolevulinic acid, methyl aminolevulinate) and diverse light sources (light-emitting diodes, lasers, intense pulsed light) have been used with promising results. An improvement of lentigines, skin roughness, fine lines and sallow complexion has been achieved with PDT. These clinically evident effects are at least in part due to histologically proven increase of collagen and decrease of elastotic material in the dermis. Effective improvement of photoaged skin, simultaneous treatment and possibly also prevention of actinic keratoses, the possibility of repeated treatments and, in contrast to other procedures, limited and calculable side effects make PDT a promising procedure for skin rejuvenation.
authors.affiliation: Department of Dermatology, University Clinic of Regensburg, Franz-Josef-Strauss-Allee 11, Regensburg, Germany sigrid.karrer@klinik.uni-regensburg.de
authors.forename: Sigrid
authors.initials: S
authors.lastname: Karrer
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Kohl
authors.forename: Konstantin
authors.initials: K
authors.lastname: Feise
authors.forename: Dagmar
authors.initials: D
authors.lastname: Hiepe-Wegener
authors.forename: Stephan
authors.initials: S
authors.lastname: Lischner
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Philipp-Dormston
authors.forename: Maurizio
authors.initials: M
authors.lastname: Podda
authors.forename: Welf
authors.initials: W
authors.lastname: Prager
authors.forename: Torsten
authors.initials: T
authors.lastname: Walker
authors.forename: Rolf-Markus
authors.initials: RM
authors.lastname: Szeimies
mesh_terms: D003357:Cosmetic Techniques; D006801:Humans; D055623:Keratosis, Actinic / Q000188:drug therapy*; D010778:Photochemotherapy / Q000379:methods*; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D015595:Skin Aging / Q000187:drug effects*
chemical_list: D017319:Photosensitizing Agents