title: Mid-upper arm circumference based nutrition programming: evidence for a new approach in regions with high burden of acute malnutrition.
abstract: BACKGROUND
  In therapeutic feeding programs (TFP), mid-upper arm circumference (MUAC) shows advantages over weight-for-height Z score (WHZ) and is recommended by the World Health Organization (WHO) as an independent criterion for screening children 6-59 months old. Here we report outcomes and treatment response from a TFP using MUAC ≤118 mm or oedema as sole admission criteria for severe acute malnutrition (SAM).
  
  
  METHODS
  Patient data from September 2007 to March 2009 for children admitted by MUAC ≤118 mm or oedema to a Médecins Sans Frontières (MSF) TFP in Burkina Faso were retrospectively analyzed. Analysis included anthropometric measurements at admission and discharge, program outcomes and treatment response.
  
  
  RESULTS
  Of 24,792 patient outcomes analyzed, nearly half (48.8%; n = 12,090) were admitted with MUAC 116-118 mm. Most patients (88.7%; n = 21,983) were 6-24 months old. At admission, 52.7% (n = 5,041) of those with MUAC 116-118 mm had a WHZ <-3 SD. At discharge, 89.1% (n = 22,094) recovered (15% weight gain or oedema resolution), 7.9% (n = 1,961) defaulted, 1.5% (n = 384) failed to respond to treatment, and 1.0% (n = 260) died. Average weight gain was 5.4 g/kg/day, and average MUAC gain was 0.42 mm/day. Patients with MUAC ≤114 mm at admission had higher average daily weight and MUAC gains at discharge compared to those admitted with MUAC 116-118 mm, but those in the latter category required longer lengths of stay to achieve recovery (P<0.001).
  
  
  CONCLUSIONS
  This analysis suggests that MUAC ≤118 mm as TFP admission criterion is a useful alternative to WHZ. Regarding treatment response, rates of weight and MUAC gain were acceptable. Applying 15% weight gain as discharge criterion resulted in longer lengths of stay for less malnourished children. Since MUAC gain parallels weight gain, it may be feasible to use MUAC as both an admission and discharge criterion.
authors.affiliation: Médecins Sans Frontières, Paris, France.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Goossens
authors.forename: Yodit
authors.initials: Y
authors.lastname: Bekele
authors.forename: Oliver
authors.initials: O
authors.lastname: Yun
authors.forename: Géza
authors.initials: G
authors.lastname: Harczi
authors.forename: Marie
authors.initials: M
authors.lastname: Ouannes
authors.forename: Susan
authors.initials: S
authors.lastname: Shepherd
mesh_terms: D000886:Anthropometry; D001132:Arm; D049628:Body Size; D002050:Burkina Faso; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D044342:Malnutrition / Q000175:diagnosis* / Q000178:diet therapy*; D009313:National Health Programs; D009749:Nutrition Surveys; D016896:Treatment Outcome