title: Direct synthesis of substituted naphthalenes from 1,3-dicarbonyl compounds and 1,2-bis(halomethyl)benzenes including a novel rearrangement aromatization of benzo[c]oxepine.
abstract: An unexpected rearrangement aromatization of benzo[c]oxepine has been revealed to synthesize substituted naphthalenes. This observation was further exploited to develop an efficient approach for the construction of naphthalenes from simple and commercially available 1,3-dicarbonyl compounds and 1,2-bis(halomethyl)benzene compounds via a new domino reaction sequence.
authors.affiliation: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Hubei, Wuhan 430079, P. R. China.
authors.forename: Jun-gang
authors.initials: JG
authors.lastname: Wang
authors.forename: Meng
authors.initials: M
authors.lastname: Wang
authors.forename: Jia-chen
authors.initials: JC
authors.lastname: Xiang
authors.forename: Yan-ping
authors.initials: YP
authors.lastname: Zhu
authors.forename: Wei-jian
authors.initials: WJ
authors.lastname: Xue
authors.forename: An-xin
authors.initials: AX
authors.lastname: Wu
mesh_terms: D001555:Benzene Derivatives / Q000737:chemistry*; D001584:Benzoxepins / Q000737:chemistry*; D002384:Catalysis; D006846:Hydrocarbons, Halogenated / Q000138:chemical synthesis / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D009281:Naphthalenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001555:Benzene Derivatives; D001584:Benzoxepins; D006846:Hydrocarbons, Halogenated; D007659:Ketones; D009281:Naphthalenes