title: Quantification of retinal nerve fiber layer thickness using spectral domain optical coherence tomography in normal Indian population.
abstract: The purpose of this study was to measure peripapillary retinal nerve fiber layer thickness (RNFLT) using spectral domain optical coherence tomography (SD-OCT) in normal Indian eyes, for which, 210 normal volunteers were recruited. One eye of each subject underwent RNFL scanning at 3.4 mm circle diameter around optic nerve using SD OCT. The data were analyzed to determine RNFLT in the sample population and its variation with age and gender. The average peripapillary RNFLT was 114.03 ± 9.59 μm. There was no effect of gender on RNFLT parameters. Age had significant negative correlation with average (P = 0.005), superior (P = 0.04), temporal (P = 0.049), and nasal quadrants (P = 0.01) RNFLT. Inferior quadrant RNFLT also had a negative correlation with age, but it was not statistically significant (P = 0.15).
authors.affiliation: Vasan Eye Care, Secunderabad, Andhra Pradesh, India.
authors.forename: Tarannum
authors.initials: T
authors.lastname: Mansoori
authors.forename: Kalluri
authors.initials: K
authors.lastname: Viswanath
authors.forename: Nagalla
authors.initials: N
authors.lastname: Balakrishna
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007194:India; D008297:Male; D009412:Nerve Fibers; D012016:Reference Values; D012030:Refractive Errors / Q000175:diagnosis; D012165:Retinal Ganglion Cells / Q000166:cytology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*