title: Sleep medicine pharmacotherapeutics overview: today, tomorrow, and the future (Part 1: insomnia and circadian rhythm disorders).
abstract: Over the past 10 years, significant strides have been made in the understanding, development, and availability of sleep disorder therapeutics. In this review series, we discuss the current evidence surrounding the mechanisms of actions, indications, efficacy, and adverse side effects associated with the available armamentarium of sleep over-the-counter and pharmacotherapeutics. This article is the first of a two-part series that covers the therapeutics for insomnia and circadian rhythm disorders.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, MD. Electronic address: sgulyan1@jhmi.edu.
authors.forename: Seema
authors.initials: S
authors.lastname: Gulyani
authors.affiliation: Department of Neurology, Johns Hopkins University, Baltimore, MD.
authors.forename: Rachel E
authors.initials: RE
authors.lastname: Salas
authors.affiliation: Department of Neurology, Johns Hopkins University, Baltimore, MD.
authors.forename: Charlene E
authors.initials: CE
authors.lastname: Gamaldo
mesh_terms: D004358:Drug Therapy / Q000639:trends*; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D004366:Nonprescription Drugs / Q000009:adverse effects / Q000627:therapeutic use; D020178:Sleep Disorders, Circadian Rhythm / Q000188:drug therapy*; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy*; D012893:Sleep Wake Disorders / Q000188:drug therapy*; D016896:Treatment Outcome; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D004366:Nonprescription Drugs