title: The N-leap method for stochastic simulation of coupled chemical reactions.
abstract: Numerical simulation of the time evolution of a spatially homogeneous chemical system is always of great interest. Gillespie first developed the exact stochastic simulation algorithm (SSA), which is accurate but time-consuming. Recently, many approximate schemes of the SSA are proposed to speed up simulation. Presented here is the N-leap method, which guarantees the validity of the leap condition and at the same time keeps the efficiency. In many cases, N-leap has better performance than the widely-used τ-leap method. The details of the N-leap method are described and several examples are presented to show its validity.
authors.affiliation: Department of Physics, Tsinghua University, Beijing 100084, China.
authors.forename: Yuting
authors.initials: Y
authors.lastname: Xu
authors.forename: Yueheng
authors.initials: Y
authors.lastname: Lan
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D008954:Models, Biological