title: Mucosal associated invariant T cells: don't forget your vitamins.
abstract: T lymphocytes express clonal receptors, called T cell receptors (TCRs), which specifically recognize antigens presented in combination with major histocompatibility molecules (MHC). To date, T cell antigens can be broadly categorized into two classes: peptides and lipids. A recent paper published in Nature by Kjer-Nielsen and colleagues reveals that a unique population of T lymphocytes expresses TCRs that recognize a completely new and unexpected class of antigens, vitamin metabolites.
authors.affiliation: Integrated Department of Immunology, National Jewish Health and University of Colorado School of Medicine, Denver, CO 80206, USA.
authors.forename: Mary H
authors.initials: MH
authors.lastname: Young
authors.forename: Laurent
authors.initials: L
authors.lastname: Gapin
mesh_terms: D005492:Folic Acid / Q000378:metabolism*; D015395:Histocompatibility Antigens Class I / Q000737:chemistry* / Q000276:immunology*; D006801:Humans; D011622:Pterins / Q000737:chemistry* / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D015395:Histocompatibility Antigens Class I; D011622:Pterins; D005492:Folic Acid