title: In vitro antimicrobial activity of Persian shallot (Allium hirtifolium).
abstract: Allium hirtifolium is a Persian native plant grown in cool mountain slopes of Iran. It has been used as a spice in Iran for many years. According to the literature review, there are no considerable reports on the antimicrobial properties of this plant. In this study, the antimicrobial activity of Persian shallot hydroalcoholic extract and F1 fraction of the plant (containing amino acid derivatives and/or other cationic compounds) was investigated on some Gram positive cocci and bacilli, Gram negative bacilli, two protozoa, a yeast and a fungus. Excellent activity against Candida albicans (MIC = 64 microg/ml, MBC = 128 microg/ml), Leishmania infantum (MIC = 0.2 mg/ml on the first day of study) and Trichomonas vaginalis (MIC = 5 microg/ml in PSDE form) and a moderate activity against Bacillus spp and Pseudomonas aeroginosa (MIC = 128 microg/ml) was observed. The results showed that this plant contains some anti-trichomonas and anti-leishmania components.
authors.affiliation: Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Setareh
authors.initials: S
authors.lastname: Soroush
authors.forename: Morovat
authors.initials: M
authors.lastname: Taherikalani
authors.forename: Parisa
authors.initials: P
authors.lastname: Asadollahi
authors.forename: Khairollah
authors.initials: K
authors.lastname: Asadollahi
authors.forename: Mojtaba
authors.initials: M
authors.lastname: Taran
authors.forename: Mohammad
authors.initials: M
authors.lastname: Emaneini
authors.forename: Sajjad
authors.initials: S
authors.lastname: Alizadeh
mesh_terms: D000490:Allium; D000890:Anti-Infective Agents / Q000494:pharmacology*; D018314:Leishmania infantum / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D014246:Trichomonas vaginalis / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D010936:Plant Extracts