title: Synthesis and ring openings of cinnamate-derived N-unfunctionalised aziridines.
abstract: tert-Butyl cinnamates are aziridinated with high trans-selectivity by an N-N ylide generated in situ from N-methylmorpholine and O-diphenylphosphinyl hydroxylamine. The resulting N-unfunctionalised aziridines are shown to be versatile synthetic building blocks that undergo highly selective ring-opening reactions with a wide range of nucleophiles.
authors.affiliation: Department of Chemistry, Imperial College London, South Kensington, London, SW7 2AZ, U.K.
authors.forename: Alan
authors.initials: A
authors.lastname: Armstrong
authors.forename: Alexandra
authors.initials: A
authors.lastname: Ferguson