title: Practical recommendations for the management of children with endemic Burkitt lymphoma (BL) in a resource limited setting.
abstract: Treatment recommendations for endemic Burkitt lymphoma (BL) in settings with only minimum requirements for curative treatment (PODC setting 1) are described. The reported cure rate for endemic BL is usually <50%. Facilities within setting 1 differ. Three treatment schedules are proposed based on: (1) when accurate staging is not possible, (2) when staging is possible and for (3) relapses and poor responders to primary therapy. A literature review and personal experience were used to formulate the recommendations. Recorded 1-year event free survival was 48% for treatment 1, 61% for treatment 2, and 35% for the rescue treatment.
authors.affiliation: Department of Paediatrics and Child Health, University of Stellenbosch, Cape Town, South Africa. pbh@sun.ac.za
authors.forename: Peter
authors.initials: P
authors.lastname: Hesseling
authors.forename: Trijn
authors.initials: T
authors.lastname: Israels
authors.forename: Mhamed
authors.initials: M
authors.lastname: Harif
authors.forename: Guillermo
authors.initials: G
authors.lastname: Chantada
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Molyneux
mesh_terms: D002051:Burkitt Lymphoma / Q000175:diagnosis* / Q000628:therapy*; D002648:Child; D003906:Developing Countries; D006295:Health Resources; D006801:Humans