title: Effect of cadence regulation on muscle activation patterns during robot assisted gait: a dynamic simulation study.
abstract: Cadence or stride frequency is an important parameter being controlled in gait training of neurologically impaired subjects. The aim of this study was to examine the effects of cadence variation on muscle activation patterns during robot assisted unimpaired gait using dynamic simulations. A twodimensional (2-D) musculoskeletal model of human gait was developed considering eight major muscle groups along with existing ground contact force (GCF) model. A 2-D model of a robotic orthosis was also developed which provides actuation to the hip, knee and ankle joints in the sagittal plane to guide subjects limbs on reference trajectories. A custom inverse dynamics algorithm was used along with a quadratic minimization algorithm to obtain a feasible set of muscle activation patterns. Predicted patterns of muscle activations during slow, natural and fast cadence were compared and the mean muscle activations were found to be increasing with an increase in cadence. The proposed dynamic simulation provide important insight into the muscle activation variations with change in cadence during robot assisted gait and provide the basis for investigating the influence of cadence regulation on neuromuscular parameters of interest during robot assisted gait.
authors.forename: Shahid
authors.initials: S
authors.lastname: Hussain
authors.forename: Sheng Q
authors.initials: SQ
authors.lastname: Xie
authors.forename: Prashant K
authors.initials: PK
authors.lastname: Jamwal
mesh_terms: D000465:Algorithms; D001696:Biomechanical Phenomena / Q000502:physiology; D003198:Computer Simulation; D005684:Gait / Q000502:physiology*; D020233:Gait Disorders, Neurologic / Q000534:rehabilitation; D006801:Humans; D007596:Joints / Q000502:physiology; D035002:Lower Extremity / Q000502:physiology*; D008954:Models, Biological; D018482:Muscle, Skeletal / Q000502:physiology*; D009989:Orthotic Devices; D012371:Robotics / Q000295:instrumentation*; D019415:Torque