title: Switching photonic and electrochemical functions of a DNAzyme by DNA machines.
abstract: DNA nanostructures acting as DNA machines are described. Specifically, DNA "walkers" assembled on nucleic acid scaffolds and triggered by fuel/antifuel strands are activated in solution or on surfaces, for example, electrodes or semiconductor CdSe/ZnS quantum dots (QDs). The DNA machines led to the switchable formation or dissociation of the hemin/G-quadruplex DNAzyme on the DNA scaffolds. This enabled the chemiluminescence, chemiluminescence resonance energy transfer (CRET), electrochemical, or photoelectrochemical transduction of the switchable states of the different DNA machines.
authors.affiliation: Institute of Chemistry, Center for Nanoscience and Nanotechnology, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
authors.forename: Xiaoqing
authors.initials: X
authors.lastname: Liu
authors.forename: Angelica
authors.initials: A
authors.lastname: Niazov-Elkan
authors.forename: Fuan
authors.initials: F
authors.lastname: Wang
authors.forename: Itamar
authors.initials: I
authors.lastname: Willner
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D017931:DNA Primers; D021881:DNA, Catalytic / Q000737:chemistry*; D055664:Electrochemical Techniques; D004735:Energy Transfer; D017785:Photons
chemical_list: D017931:DNA Primers; D021881:DNA, Catalytic; D004247:DNA