title: Effects of a coating resin containing S-PRG filler to prevent demineralization of root surfaces.
abstract: The purpose of this study was to evaluate the ability of a coating material containing the surface pre-reacted glass-ionomer (S-PRG) filler to protect the root from demineralization in vitro. The proprietary coating resin containing the S-PRG filler (PRG Barrier Coat) was applied to human root dentin and immersed in acid buffer at pH 4.5 for 3 d. Demineralization was evaluated by micro-CT scanning and the dentin-material interface observed by scanning electron microscopy. The ability of the coating resin to modify acid production by Streptococcus mutans was investigated by monitoring pH using an ion-sensitive field-effect transistor pH electrode. Application of PRG Barrier Coat produced a coating layer with the thickness of approximately 200 µm and completely inhibited demineralization. The bacteria-induced pH fall at the material surface was significantly inhibited. We conclude that S-PRG fillercontaining coating resin may be an effective material for protecting exposed root from both chemical and biological challenges.
authors.affiliation: Department of Prosthodontics, School of Stomatology, Fourth Military Medical University, Xi’an 710032, P.R. China.
authors.forename: Sai
authors.initials: S
authors.lastname: Ma
authors.forename: Satoshi
authors.initials: S
authors.lastname: Imazato
authors.forename: Ji-Hua
authors.initials: JH
authors.lastname: Chen
authors.forename: Gen
authors.initials: G
authors.lastname: Mayanagi
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Takahashi
authors.forename: Takuya
authors.initials: T
authors.lastname: Ishimoto
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Nakano
mesh_terms: D020099:Coated Materials, Biocompatible; D003804:Dentin / Q000187:drug effects*; D006801:Humans; D006863:Hydrogen-Ion Concentration / Q000187:drug effects; D017736:Ion-Selective Electrodes; D008855:Microscopy, Electron, Scanning; D009943:Organophosphorus Compounds; D012117:Resins, Synthetic; D017213:Root Caries / Q000517:prevention & control*; D013295:Streptococcus mutans / Q000378:metabolism; D013499:Surface Properties; D017001:Tooth Demineralization / Q000517:prevention & control*; D014092:Tooth Root / Q000187:drug effects*; D055114:X-Ray Microtomography
chemical_list: D020099:Coated Materials, Biocompatible; D009943:Organophosphorus Compounds; D012117:Resins, Synthetic; C472422:S-PPG compound