title: A case of angiomyolipoma of the spermatic cord and testicle.
abstract: Angiomyolipomas (AML) are mesenchymal tumors of the kidney consisting of varying proportions of vascular, immature smooth muscle and mature fat cells. A rare case of testicular AML is described. A 53 year old male with a history of congenital motor defects, mental retardation, and hypertension, presented to the emergency room with sudden onset, severe left testicular pain. Scrotal sonography demonstrated an hypoechoic mass in the patient's left testicle. The patient was offered and underwent a trans-inguinal exploration of the left testicle which ended in a left inguinal orchiectomy. Pathologic examination of the mass revealed medium to large calibre thick-walled blood vessels with ectatic lumina, surround by sclerotic, fibrous smooth muscle bundles in a fatty milieu. Immunohistochemistry of the lesion demonstrated positive staining for smooth muscle actin (SMA+) and endothelial marker CD34. The lesion did not, however, stain positively for smooth muscle antigen S100 or melanocytic antigen HMB-45.
authors.affiliation: Villa Tiberia Clinic, Urology Department, Rome, Italy. roberto.giulianelli@virgilio.it
authors.forename: Roberto
authors.initials: R
authors.lastname: Giulianelli
authors.forename: Luca
authors.initials: L
authors.lastname: Albanesi
authors.forename: Francesco
authors.initials: F
authors.lastname: Attisani
authors.forename: Stefano
authors.initials: S
authors.lastname: Brunori
authors.forename: Barbara Cristina
authors.initials: BC
authors.lastname: Gentile
authors.forename: Luca
authors.initials: L
authors.lastname: Mavilla
authors.forename: Gabriella
authors.initials: G
authors.lastname: Mirabile
authors.forename: Francesco
authors.initials: F
authors.lastname: Pisanti
authors.forename: Giorgio
authors.initials: G
authors.lastname: Vincenti
authors.forename: Teuta
authors.initials: T
authors.lastname: Shestani
authors.forename: Manlio
authors.initials: M
authors.lastname: Schettini
mesh_terms: D018207:Angiomyolipoma / Q000175:diagnosis; D005834:Genital Neoplasms, Male / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis; D013085:Spermatic Cord; D013736:Testicular Neoplasms / Q000175:diagnosis