title: Supracricoid laryngectomy with cricohyoidoepiglottopexy (CHEP) in the management of laryngeal carcinoma: oncologic results. A 35-year experience.
abstract: To evaluate the long-term oncologic results of supracricoid laryngectomy with cricohyoidoepiglottopexy (CHEP) for laryngeal cancer. A 35-year retrospective study concerning 291 patients treated by supracricoid laryngectomy with CHEP for laryngeal cancer was performed. The following postoperative data were studied: recurrence rates (lymph node and laryngeal), distant metastases and second cancer. The mortality rate and overall survival were estimated by the Kaplan-Meier method. The postoperative mortality was 1.03 %. 23 patients were lost to follow-up. The 3-year survival rate was 84 % and the 5-year survival rate was 80 %. 12 patients developed distant metastasis. 31 patients developed a second cancer. The local (laryngeal) control rate was 93.94 % and the regional (cervical lymph node) control rate was 92.05 %. In multivariate analysis, the occurrence of a second non-ENT cancer and metastasis as well as margins involvement were reliable to mortality. Supracricoid laryngectomy with CHEP appears to be associated with very good long-term oncologic results and still has a place in the management of T1, T2 and selected T3 glottic cancers.
authors.affiliation: ENT and Head and Neck Surgery Department, University Hospital of Amiens, Amiens, France. cyril_page@yahoo.fr
authors.forename: C
authors.initials: C
authors.lastname: Page
authors.forename: G
authors.initials: G
authors.lastname: Mortuaire
authors.forename: F
authors.initials: F
authors.lastname: Mouawad
authors.forename: O
authors.initials: O
authors.lastname: Ganry
authors.forename: J
authors.initials: J
authors.lastname: Darras
authors.forename: X
authors.initials: X
authors.lastname: Pasquesoone
authors.forename: D
authors.initials: D
authors.lastname: Chevalier
mesh_terms: D000328:Adult; D000368:Aged; D003413:Cricoid Cartilage / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome