title: Genome sequence of Coxiella burnetii 109, a doxycycline-resistant clinical isolate.
abstract: Coxiella burnetii 109, with a 2.03-Mb genome, is a doxycycline-resistant human isolate that was isolated from the cardiac valve of a German male patient with Q fever endocarditis who died during the course of the treatment due to the bacterium's resistance to doxycycline. This new genome can be useful for future comparative genomic or Q fever studies.
authors.affiliation: Aix Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095, Marseille, France.
authors.forename: Laetitia
authors.initials: L
authors.lastname: Rouli
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Rolain
authors.forename: Adil
authors.initials: A
authors.lastname: El Filali
authors.forename: Catherine
authors.initials: C
authors.lastname: Robert
authors.forename: Didier
authors.initials: D
authors.lastname: Raoult
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016997:Coxiella burnetii / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D004269:DNA, Bacterial / Q000235:genetics; D004318:Doxycycline / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D016680:Genome, Bacterial; D006351:Heart Valves / Q000382:microbiology; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D011778:Q Fever / Q000382:microbiology*; D017422:Sequence Analysis, DNA
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D004318:Doxycycline