title: Effect of precursor's solubility on the mechanical property of hydroxyapatite formed by dissolution-precipitation reaction of tricalcium phosphate.
abstract: The effect of the solubility of the precursors, alpha tricalcium phosphate (α-TCP) and beta tricalcium phosphate (β-TCP) on the mechanical strength of hydroxyapatite (HAp) bone substitute was investigated. Uniaxially pressed block starting from these precursors were treated hydrothermally with 1 mol/L of ammonia solution at 200°C for various durations. XRD analysis revealed that α-TCP block took 3 h whereas β-TCP block took 240 h for complete transformation to HAp. The porosity of HAp obtained from β-TCP block was found to be lower than that of HAp from α-TCP block. Diametral tensile strength of HAp from β-TCP block showed a significantly higher value than that of HAp from α-TCP block. It is therefore concluded that solubility of precursor affects the mechanical strength of the HAp block.
authors.affiliation: Department of Biomaterials, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: Nurazreena
authors.initials: N
authors.lastname: Ahmad
authors.forename: Kanji
authors.initials: K
authors.lastname: Tsuru
authors.forename: Melvin L
authors.initials: ML
authors.lastname: Munar
authors.forename: Michito
authors.initials: M
authors.lastname: Maruta
authors.forename: Shigeki
authors.initials: S
authors.lastname: Matsuya
authors.forename: Kunio
authors.initials: K
authors.lastname: Ishikawa
mesh_terms: D018786:Bone Substitutes / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003799:Dental Stress Analysis; D017886:Durapatite / Q000138:chemical synthesis* / Q000737:chemistry; D016062:Porosity; D012995:Solubility; D013718:Tensile Strength
chemical_list: D018786:Bone Substitutes; D002130:Calcium Phosphates; D017886:Durapatite; C018392:tricalcium phosphate