title: Do antibacterial mouthrinses affect bacteraemia in third molar surgery? A pilot study.
abstract: BACKGROUND
  The aim of this pilot study was to evaluate the effects of mouthrinses containing 7.5% povidone iodine and 0.2% chlorhexidine on bacteraemia following impacted third molar surgery.
  
  
  METHODS
  Thirty-four patients were enrolled in this study. Patients in the first group were asked to rinse their mouth with the mouthrinse containing 7.5% povidone iodine, patients in the second group were asked to rinse with the mouthrinse containing 0.2% chlorhexidine and patients in the third group were asked to rinse with 0.9% NaCl (sterile saline) solution. All rinses were used for one minute preoperatively. Peripheral venous blood samples were collected at baseline (preoperatively), 1 and 15 minutes after the completion of surgical tooth removal. Each blood sample was divided in two, placed in aerobic and anaerobic culture bottles and processed for microbiological examination.
  
  
  RESULTS
  Bactaeremia was detected in 33% of the povidone iodine group, 33% of the chlorhexidine group and 50% of the control group. Isolated bacteria were 58% anaerobes and predominantly 92%Streptococcus species. Incidence of bacteraemia was reduced with chlorhexidine and povidone iodine mouthrinses in third molar surgery, although the difference was not statistically significant (p > 0.05).
  
  
  CONCLUSIONS
  Bacteraemia was reduced with antibacterial mouthrinses in third molar surgery. The results of this study should be confirmed with further studies conducted on a larger patient population and with different antibacterial mouthrinses.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Yeditepe University, Istanbul, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Tuna
authors.forename: C
authors.initials: C
authors.lastname: Delilbasi
authors.forename: A
authors.initials: A
authors.lastname: Arslan
authors.forename: Y
authors.initials: Y
authors.lastname: Gurol
authors.forename: Z
authors.initials: Z
authors.lastname: Tazegun Tekkanat
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016470:Bacteremia / Q000175:diagnosis / Q000188:drug therapy*; D001421:Bacteria, Anaerobic / Q000187:drug effects; D002710:Chlorhexidine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008964:Molar, Third / Q000601:surgery*; D009067:Mouthwashes / Q000737:chemistry / Q000627:therapeutic use*; D010865:Pilot Projects; D011206:Povidone-Iodine / Q000627:therapeutic use*; D011300:Preoperative Care; D013291:Streptococcus / Q000187:drug effects; D014081:Tooth Extraction / Q000009:adverse effects; D014095:Tooth, Impacted / Q000601:surgery*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D009067:Mouthwashes; D011206:Povidone-Iodine; D002710:Chlorhexidine