title: Risk of cancer mortality in spanish towns lying in the vicinity of pollutant industries.
abstract: Spatial aggregation of different industrial facilities leads to simultaneous release of pollutant emissions. Our objective is to study cancer mortality risk associated with residence in the vicinity of pollutant factories. We used data on industries for year 2007 (3458 facilities). For the 8,098 Spanish towns, we defined a factor with 4 levels based on the number of factories in a radius of 2.5 km from the centroid of each town (industrial factor). We also used data of land cover use to approximate the percentage of municipal land used for industrial activities in each Spanish town (land-used variable). For both variables we fitted Poisson models with random terms to account for spatial variation. We estimated risk trends related with increasing number of factories or percentage of land used for industrial activities. We studied 33 cancer causes. For the industrial factor, 11 causes showed trend associated with increasing factor level. For the land use variable, 8 causes showed statistically significant risks. Almost all tumours related to the digestive system and the respiratory system showed increased risks. Thus mortality by these tumours could be associated to residence in towns nearby industrial areas with positive trend linked to increasing levels of industrial activity.
authors.affiliation: Department of Environmental Epidemiology and Cancer, National Centre for Epidemiology, Carlos III Institute of Health, Avenida Monforte de Lemos, 5, 28029 Madrid, Spain ; CIBER en Epidemiología y Salud Pública (CIBERESP), 08003 Madrid, Spain ; Division of Medicine, Lancaster University, Lancaster LA1 4YB, UK.
authors.forename: Rebeca
authors.initials: R
authors.lastname: Ramis
authors.forename: Pablo
authors.initials: P
authors.lastname: Fernandez-Navarro
authors.forename: Javier
authors.initials: J
authors.lastname: Garcia-Perez
authors.forename: Elena
authors.initials: E
authors.lastname: Boldo
authors.forename: Diana
authors.initials: D
authors.lastname: Gomez-Barroso
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Lopez-Abente