title: [Impact of high altitude and hypoxia on sperm concentration].
abstract: Recent studies show that long exposure to high altitude and hypoxia can seriously affect men's reproductive health by reducing their sperm concentration, which decreases with the increase of altitude. High altitude and hypoxia are strongly associated with spermatogenic reduction, sperm DNA damage, sperm apoptosis, and decreased level of sex hormones. This article reviews the mechanisms of high altitude and hypoxia affecting sperm concentration.
authors.affiliation: The Second School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu 730030, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Wan
authors.forename: Yang-Min
authors.initials: YM
authors.lastname: Wang
mesh_terms: D000531:Altitude; D006801:Humans; D000860:Hypoxia; D008297:Male; D013076:Sperm Count; D013091:Spermatogenesis; D013094:Spermatozoa / Q000502:physiology*