title: Enterohemorrhagic Escherichia coli O157:H7 survival in an in vitro model of the human large intestine and interactions with probiotic yeasts and resident microbiota.
abstract: This is the first report on the fate of enterohemorrhagic Escherichia coli O157:H7 in simulated human colonic conditions. The pathogen was progressively eliminated from the bioreactor and did not modify the major populations of resident microbiota. The coadministration of the Saccharomyces cerevisiae CNCM I-3856 probiotic strain led to a significant increase in acetate production but did not reduce pathogen viability.
authors.affiliation: Clermont Université, Université d'Auvergne, Centre de Recherche en Nutrition Humaine Auvergne, EA 4678 CIDAM, Conception Ingénierie et Développement de l'Aliment et du Médicament, Clermont-Ferrand, France.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Thévenot
authors.forename: Lucie
authors.initials: L
authors.lastname: Etienne-Mesmin
authors.forename: Sylvain
authors.initials: S
authors.lastname: Denis
authors.forename: Sandrine
authors.initials: S
authors.lastname: Chalancon
authors.forename: Monique
authors.initials: M
authors.lastname: Alric
authors.forename: Valérie
authors.initials: V
authors.lastname: Livrelli
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Blanquet-Diot
mesh_terms: D019149:Bioreactors / Q000382:microbiology; D019453:Escherichia coli O157 / Q000502:physiology*; D006801:Humans; D007420:Intestine, Large / Q000382:microbiology*; D054892:Metagenome; D056265:Microbial Interactions; D050296:Microbial Viability; D008962:Models, Theoretical; D019936:Probiotics / Q000494:pharmacology*; D012441:Saccharomyces cerevisiae / Q000502:physiology*