title: Bioanalytical and instrumental analysis of estrogenic activities in drinking water sources from Yangtze River Delta.
abstract: The estrogenic activities of source water from Yangtze River, Huaihe River, Taihu Lake and groundwater in Yangtze River Delta in the dry and wet season were determined by use of reporter gene assays based on African green monkey kidney (CV-1) cell lines. Higher estrogenic activities were observed in the dry season, and the estrogenic potentials in water samples from Taihu Lake were greater than other river basins. None of the samples from groundwater showed estrogen receptor (ER) agonist activity. The 17β-Estradiol (E2) equivalents (EEQs) of water samples in the dry season ranged from 9.41×10(-1) to 1.20×10(1) ng E2 L(-1). In the wet season, EEQs of all the water samples were below the detection limit as 9.00×10(-1) ng E2 L(-1) except for one sample from Huaihe River. The highest contribution of E2 was detected in Yangtze River as 99% of estrogenic activity. Nonylphenol (NP, 100% detection rate) and octylphenol (OP, 100% detection rate) might also be responsible for the estrogenic activities in water sources. Potential health risk induced by the estrogenic chemicals in source water may be posed to the residents through water drinking.
authors.affiliation: State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing 210023, People's Republic of China.
authors.forename: Xinxin
authors.initials: X
authors.lastname: Hu
authors.forename: Wei
authors.initials: W
authors.lastname: Shi
authors.forename: Fu
authors.initials: F
authors.lastname: Cao
authors.forename: Guanjiu
authors.initials: G
authors.lastname: Hu
authors.forename: Yingqun
authors.initials: Y
authors.lastname: Hao
authors.forename: Si
authors.initials: S
authors.lastname: Wei
authors.forename: Xinru
authors.initials: X
authors.lastname: Wang
authors.forename: Hongxia
authors.initials: H
authors.lastname: Yu
mesh_terms: D060766:Drinking Water / Q000737:chemistry*; D052244:Endocrine Disruptors / Q000032:analysis; D004784:Environmental Monitoring; D004967:Estrogens / Q000032:analysis*; D060587:Groundwater / Q000737:chemistry; D045483:Rivers / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis*; D014877:Water Pollution, Chemical / Q000706:statistics & numerical data; D014881:Water Supply / Q000706:statistics & numerical data*
chemical_list: D060766:Drinking Water; D052244:Endocrine Disruptors; D004967:Estrogens; D014874:Water Pollutants, Chemical