title: No difference in clinical outcome between fixed- and mobile-bearing TKA: a meta-analysis.
abstract: OBJECTIVE
  To compare the clinical and radiographic results of fixed-bearing and mobile-bearing total knee arthroplasty (TKA).
  
  
  METHODS
  We searched the PubMed, Medline, Embase, Cochrane Central Register of Controlled Trials, and Google Scholar databases from 1966 to January 2012. No language restriction was applied. Reference lists of all the selected articles were hand-searched for any additional trials. Trial quality was assessed using the modified Jadad scale. Two authors independently extracted data from all eligible studies, including study design, participants, interventions, and outcomes (Knee Society Score, range of movement, radiolucent line, patient preference, walking support, pain score, and complications). The data were using fixed-effects or random-effects models with mean differences and risk ratios for continuous and dichotomous variables, respectively.
  
  
  RESULTS
  A total of 24 studies involving 2,799 patients were identified in this analysis. Meta-analysis showed lower pain score (OR, 0.66, 95% CI 0.46, 0.94) in mobile-bearing TKA than fixed-bearing TKA. There was no significant difference between the two treatment groups regarding Knee Society Score (SMD, -0.17, 95% CI: -0.60, 0.26), range of movement (SMD, -0.05, 95% CI: -0.63, 0.53), radiolucent line (OR, 1.03, 95% CI 0.74, 1.44), patient preference (OR, 1.15, 95% CI 0.82, 1.61), walking support (OR, 1.07, 95% CI 0.68, 1.70), and complications (OR, 0.85, 95% CI 0.59, 1.21).
  
  
  CONCLUSIONS
  The available evidence suggested that there was no significant difference between clinical and radiographic results of fixed-bearing and mobile-bearing TKA except for pain score. Regarding clinical relevance, the less incidence of pain could be the advantage for selecting mobile-bearing TKA.
  
  
  METHODS
  II.
authors.affiliation: Department of Orthopaedics, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin, 300052, People's Republic of China.
authors.forename: Yu-Lin
authors.initials: YL
authors.lastname: Li
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wu
authors.forename: Guang-Zhi
authors.initials: GZ
authors.lastname: Ning
authors.forename: Shi-Qing
authors.initials: SQ
authors.lastname: Feng
authors.forename: Qiu-Li
authors.initials: QL
authors.lastname: Wu
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Yan
authors.initials: Y
authors.lastname: Hao
mesh_terms: D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation*; D006801:Humans; D007720:Knee Prosthesis; D015233:Models, Statistical; D017063:Outcome Assessment, Health Care; D010149:Postoperative Pain / Q000517:prevention & control