title: Allylation of functionalized aldehydes by potassium allyltrifluoroborate catalyzed by 18-crown-6 in aqueous media.
abstract: An efficient method for the allylation of aldehydes containing a broad range of functional groups using potassium allyltrifluoroborate is described. The reaction utilizes a catalytic amount of 18-C-6 in biphasic media under open atmosphere and room temperature to provide the corresponding homoallylic alcohols in high yields and without the necessity of any subsequent purification.
authors.affiliation: Departamento de Química Fundamental, Universidade Federal de Pernambuco, Av. Jornalista Aníbal Fernandes, s/n - Cidade Universitária, Recife - PE 50740-560, Brazil.
authors.forename: Fernanda C G
authors.initials: FC
authors.lastname: Barbosa
authors.forename: Juliano C R
authors.initials: JC
authors.lastname: Freitas
authors.forename: Caio F
authors.initials: CF
authors.lastname: Melo
authors.forename: Paulo H
authors.initials: PH
authors.lastname: Menezes
authors.forename: Roberta A
authors.initials: RA
authors.lastname: Oliveira
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D001881:Borates / Q000737:chemistry; D002384:Catalysis; D043844:Crown Ethers / Q000737:chemistry; D011188:Potassium / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D000447:Aldehydes; D001881:Borates; D043844:Crown Ethers; D014867:Water; C015762:18-crown-6; C098759:fluoroboric acid; D011188:Potassium