title: Community-associated methicillin-resistant Staphylococcus aureus necrotizing pneumonia in a healthy neonate.
abstract: The number of cases of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) pneumonia has increased since the late 1990s, with skin and soft tissue infections predominant among neonates. Herein, we present a rare case of CA-MRSA necrotizing pneumonia with empyema following respiratory syncytial virus (RSV) infection in a healthy neonate. Despite prompt vancomycin treatment, the disease worsened and finally we had to perform pneumonectomy. This case highlights the possibility of emerging CA-MRSA-related invasive disease among neonates.
authors.affiliation: Division of Neonatology, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan; Division of Pediatric General Medicine, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan.
authors.forename: Wai Ho
authors.initials: WH
authors.lastname: Lim
authors.affiliation: Division of Neonatology, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan. Electronic address: reyinl@adm.cgmh.org.tw.
authors.forename: Reyin
authors.initials: R
authors.lastname: Lien
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan.
authors.forename: Yhu-Chering
authors.initials: YC
authors.lastname: Huang
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, Taiwan.
authors.forename: Wen Jen
authors.initials: WJ
authors.lastname: Lee
authors.affiliation: Division of Pediatric Surgery, Department of Surgery, Chang Gung Children's Hospital, Taoyuan, Taiwan.
authors.forename: Jing Yao
authors.initials: JY
authors.lastname: Lai
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017714:Community-Acquired Infections / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D004653:Empyema / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000473:pathology*; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification*; D009336:Necrosis / Q000473:pathology*; D011013:Pneumonectomy; D011023:Pneumonia, Staphylococcal / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology* / Q000473:pathology; D018357:Respiratory Syncytial Virus Infections / Q000175:diagnosis / Q000473:pathology; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin