title: WormQTL--public archive and analysis web portal for natural variation data in Caenorhabditis spp.
abstract: Here, we present WormQTL (http://www.wormqtl.org), an easily accessible database enabling search, comparative analysis and meta-analysis of all data on variation in Caenorhabditis spp. Over the past decade, Caenorhabditis elegans has become instrumental for molecular quantitative genetics and the systems biology of natural variation. These efforts have resulted in a valuable amount of phenotypic, high-throughput molecular and genotypic data across different developmental worm stages and environments in hundreds of C. elegans strains. WormQTL provides a workbench of analysis tools for genotype-phenotype linkage and association mapping based on but not limited to R/qtl (http://www.rqtl.org). All data can be uploaded and downloaded using simple delimited text or Excel formats and are accessible via a public web user interface for biologists and R statistic and web service interfaces for bioinformaticians, based on open source MOLGENIS and xQTL workbench software. WormQTL welcomes data submissions from other worm researchers.
authors.affiliation: Laboratory of Nematology, Wageningen University, Wageningen 6708 PB, The Netherlands.
authors.forename: L Basten
authors.initials: LB
authors.lastname: Snoek
authors.forename: K Joeri
authors.initials: KJ
authors.lastname: Van der Velde
authors.forename: Danny
authors.initials: D
authors.lastname: Arends
authors.forename: Yang
authors.initials: Y
authors.lastname: Li
authors.forename: Antje
authors.initials: A
authors.lastname: Beyer
authors.forename: Mark
authors.initials: M
authors.lastname: Elvin
authors.forename: Jasmin
authors.initials: J
authors.lastname: Fisher
authors.forename: Alex
authors.initials: A
authors.lastname: Hajnal
authors.forename: Michael O
authors.initials: MO
authors.lastname: Hengartner
authors.forename: Gino B
authors.initials: GB
authors.lastname: Poulin
authors.forename: Miriam
authors.initials: M
authors.lastname: Rodriguez
authors.forename: Tobias
authors.initials: T
authors.lastname: Schmid
authors.forename: Sabine
authors.initials: S
authors.lastname: Schrimpf
authors.forename: Feng
authors.initials: F
authors.lastname: Xue
authors.forename: Ritsert C
authors.initials: RC
authors.lastname: Jansen
authors.forename: Jan E
authors.initials: JE
authors.lastname: Kammenga
authors.forename: Morris A
authors.initials: MA
authors.lastname: Swertz
mesh_terms: D000818:Animals; D002107:Caenorhabditis / Q000235:genetics*; D017173:Caenorhabditis elegans / Q000235:genetics; D030541:Databases, Genetic; D015870:Gene Expression; D056726:Genetic Association Studies; D014644:Genetic Variation; D020407:Internet; D040641:Quantitative Trait Loci