title: Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome.
abstract: Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by sicca symptoms. Interstitial pulmonary fibrosis and tracheobronchial sicca are the most common symptoms of pulmonary involvement in primary SjS, and they are rarely accompanied by serositis such as pleuritis or pericarditis. We report a case of SS presenting initially with bilateral pleural effusions. A 63-year old man was admitted to our hospital with a one-month history of cough, dyspnea, and right chest pain. Chest-computed tomography revealed bilateral pleural effusions. Serum anti-SS-A antibody titer was 1 : 256. Ophthalmological examination revealed a positive Schirmer test. Lip biopsy showed atrophy and plasmacytic infiltration of the salivary gland. Corticosteroid treatment was initiated. Pleural effusions were almost completely resolved by day 30. The patient has not experienced any recurrence.
authors.affiliation: Department of Respiratory Medicine, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Minami-ku, Okayama 7028055, Japan ; Department of Respiratory Medicine, National Hospital Organization Okayama Medical Center, 1711-1 Tamasu, Kita-ku, Okayama 7011192, Japan.
authors.forename: Go
authors.initials: G
authors.lastname: Makimoto
authors.forename: Michiko
authors.initials: M
authors.lastname: Asano
authors.forename: Nobukazu
authors.initials: N
authors.lastname: Fujimoto
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Fuchimoto
authors.forename: Katsuichiro
authors.initials: K
authors.lastname: Ono
authors.forename: Shinji
authors.initials: S
authors.lastname: Ozaki
authors.forename: Koji
authors.initials: K
authors.lastname: Taguchi
authors.forename: Takumi
authors.initials: T
authors.lastname: Kishimoto