title: Photodynamic therapy combined with intravitreal bevacizumab in a patient with choroidal neovascularization secondary to choroidal osteoma.
abstract: Choroidal osteoma is a benign ossified tumor that is found predominantly in healthy young women during their second and third decades of life. The lesions are white-to-cream or orange in color, are located in the peripapillary and macular areas, and are unilateral in most patients. The symptoms of choroidal osteoma include decreased visual acuity and metamorphopsia or scotoma corresponding to the location of the osteoma, but some patients have no symptoms. Prognosis of vision varies according to tumor location, retinal pigment epithelial and sensory retinal degeneration, subretinal fluid and hemorrhage, and development of a subretinal neovascular membrane.
authors.affiliation: Department of Ophthalmology, Maryknoll Medical Center, Busan, Korea.
authors.forename: Jung Hyun
authors.initials: JH
authors.lastname: Jang
authors.forename: Keong Hwan
authors.initials: KH
authors.lastname: Kim
authors.forename: Soo Jung
authors.initials: SJ
authors.lastname: Lee
authors.forename: Jung Min
authors.initials: JM
authors.lastname: Park
mesh_terms: D020533:Angiogenesis Inhibitors / Q000008:administration & dosage; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage*; D000068258:Bevacizumab; D002830:Choroid Neoplasms / Q000150:complications* / Q000175:diagnosis; D020256:Choroidal Neovascularization / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D058449:Intravitreal Injections; D008875:Middle Aged; D010016:Osteoma / Q000150:complications* / Q000175:diagnosis; D010778:Photochemotherapy / Q000379:methods*; D041623:Tomography, Optical Coherence; D042461:Vascular Endothelial Growth Factor A / Q000037:antagonists & inhibitors; D014792:Visual Acuity
chemical_list: D020533:Angiogenesis Inhibitors; D061067:Antibodies, Monoclonal, Humanized; D042461:Vascular Endothelial Growth Factor A; D000068258:Bevacizumab