title: Tyrokeradines C-F, new bromotyrosine alkaloids from the Verongid sponges.
abstract: Four new bromotyrosine alkaloids, tyrokeradines C-F (1-4), have been isolated from Okinawan marine sponges of the order Verongidae. The structures of 1-4 were elucidated on the basis of spectroscopic data. Tyrokeradines C (1) and D (2) are new bromotyrosine alkaloids possesing an imidazole ring, while tyrokeradines E (3) and F (4) are new bromotyrosine alkaloids possesing a cyano group.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060–0812, Japan.
authors.forename: Takaaki
authors.initials: T
authors.lastname: Kubota
authors.forename: Shinya
authors.initials: S
authors.lastname: Watase
authors.forename: Hiroya
authors.initials: H
authors.lastname: Mukai
authors.forename: Jane
authors.initials: J
authors.lastname: Fromont
authors.forename: Jun'ichi
authors.initials: J
authors.lastname: Kobayashi
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011161:Porifera / Q000737:chemistry*; D014443:Tyrosine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D000470:Alkaloids; C475724:bromotyrosine; D014443:Tyrosine