title: Clinical analysis of fulminant type 1 diabetes in China and comparison with a nationwide survey in Japan.
abstract: OBJECTIVE
  To report 26 cases of fulminant type 1 diabetes found in Guangdong Medical College Futian Hospital and Central South University Second Xiangya Hospital in China and to study the difference between Chinese and Japanese patients.
  
  
  METHODS
  The clinical and biochemical characteristics of 26 patients who had been diagnosed with fulminant type 1 diabetes mellitus in China were analyzed retrospectively and then compared with those characteristics of 161 patients from a nationwide survey in Japan at the time of diagnosis and follow-up 6 months.
  
  
  RESULTS
  The mean values of the characteristics from these two data sets, including fasting and postprandial serum C-peptide concentration, serum sodium and potassium level, positive for GADAb were significantly different (P=0.003, P=0.005, P=0.035, P=0.030, P<0.001, respectively).
  
  
  CONCLUSIONS
  The clinical and biochemical characteristics of Chinese patients did not largely differ from those of Japanese patients. Further studies are needed for some unique characteristics found in our group.
authors.affiliation: Department of Endocrinology, Affiliated Futian Hospital of Guangdong Medical College, Shennan Middle Road 3025#, Shenzhen 518033, China. liul2005@hotmail.com
authors.forename: Lan
authors.initials: L
authors.lastname: Liu
authors.forename: Jiping
authors.initials: J
authors.lastname: Mao
authors.forename: Zeyuan
authors.initials: Z
authors.lastname: Lu
authors.forename: Xiaojie
authors.initials: X
authors.lastname: Yan
authors.forename: Yiyi
authors.initials: Y
authors.lastname: Ye
authors.forename: Fengxiu
authors.initials: F
authors.lastname: Jiang
mesh_terms: D000293:Adolescent; D000328:Adult; D002096:C-Peptide / Q000097:blood; D002648:Child; D002681:China / Q000453:epidemiology; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000453:epidemiology / Q000208:ethnology; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism*; D006306:Health Surveys; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D011188:Potassium / Q000097:blood; D012189:Retrospective Studies; D012964:Sodium / Q000097:blood
chemical_list: D002096:C-Peptide; D006442:Glycated Hemoglobin; D011188:Potassium; D012964:Sodium; C517652:hemoglobin A1c protein, human