title: Effects of boswellic acid of Boswellia serrata and other triterpenic acids on the complement system.
abstract: β-boswellic acid (BA), one major constituent of the resin of Boswellia serrata and other triterpenic acids of plant origin (crataegolic-, ursolic-, oleanolic- and glycyrrhetic acid) were found to possess anti-complementary activity in the classical and in the alternative complement pathway. Significant reduction of immunohemolysis in vitro was observed at BA concentrations between 0.005-0.1 mM with an IC(50) value of about 10 μmol/l.
authors.affiliation: Department of Immunology, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, CA 92037, U.S.A.
authors.forename: U
authors.initials: U
authors.lastname: Knaus
authors.forename: H
authors.initials: H
authors.lastname: Wagner