title: Encephalomyelitis by Toxoplasma gondii in a captive fossa (Cryptoprocta ferox).
abstract: Encephalomyelitis due to Toxoplasma gondii was diagnosed in a fossa (Cryptoprocta ferox). The animal had ataxia, atrophy of hind limb muscles and progressive wasting before dying 12 months after the onset of clinical signs. Toxoplasmosis was suspected antemortem based on clinical signs and the detection of T. gondii DNA by PCR on EDTA-blood from live animal. Necropsy revealed necrotizing gastritis and severe emaciation. The main histological lesions included non-suppurative encephalomyelitis, with dilation of myelin sheaths and swollen axons in the spinal cord, and multifocal gliosis in the brain with intralesional protozoan cysts that stained positive for T. gondii immunohistochemistry. To the authors' knowledge, this is the first report of toxoplasmosis in a fossa, and a new host record.
authors.affiliation: Biomedical Sciences Research Institute, Unidad de Histología y Anatomía Patológica, Facultad de Veterinaria, Universidad CEU Cardenal Herrera, Avda. Seminario, s/n, 46113 Moncada, Valencia, Spain. jmcorpa@uch.ceu.es
authors.forename: J M
authors.initials: JM
authors.lastname: Corpa
authors.forename: A
authors.initials: A
authors.lastname: García-Quirós
authors.forename: M
authors.initials: M
authors.lastname: Casares
authors.forename: A C
authors.initials: AC
authors.lastname: Gerique
authors.forename: M D
authors.initials: MD
authors.lastname: Carbonell
authors.forename: M T
authors.initials: MT
authors.lastname: Gómez-Muñoz
authors.forename: F A
authors.initials: FA
authors.lastname: Uzal
authors.forename: J
authors.initials: J
authors.lastname: Ortega
mesh_terms: D000818:Animals; D000836:Animals, Zoo; D004679:Encephalomyelitis / Q000469:parasitology / Q000662:veterinary*; D053826:Eupleridae; D017809:Fatal Outcome; D005260:Female; D014122:Toxoplasma / Q000302:isolation & purification*; D014124:Toxoplasmosis, Animal / Q000150:complications*