title: Lignocellulosic biomass as a carbohydrate source for lipid production by Mortierella isabellina.
abstract: Various carbon sources including monosugars, disaccharides and carboxymethyl-cellulose (CMC) were used for single-cell oil production by the filamentous fungus Mortierella isabellina. In addition, the inhibitory effects of lignocellulose-derived compounds (lignin aldehydes, furan aldehydes and weak acid) were investigated. C6 sugars were preferably used for growth compared to C5 sugars. CMC was not an usable substrate, implying the absence of a cellulase system in this fungus. Lignin derivatives showed the most inhibitory effects, but acetic and formic acids at concentrations of 4 g/L improved lipid production, achieving 6.81 ± 0.07 g/L and 6.66 ± 0.33 g/L respectively, which was twice as high as that of the control. A 16.8% lipid yield from hydrolysate suggested that this fungus could be useful for microbial lipid production.
authors.affiliation: Department of Biological Systems Engineering, The Bioprocessing and Bioproduct Engineering Laboratory, Washington State University, LJ Smith 213, Pullman, WA 99163, United States.
authors.forename: Jijiao
authors.initials: J
authors.lastname: Zeng
authors.forename: Yubin
authors.initials: Y
authors.lastname: Zheng
authors.forename: Xiaochen
authors.initials: X
authors.lastname: Yu
authors.forename: Liang
authors.initials: L
authors.lastname: Yu
authors.forename: Difeng
authors.initials: D
authors.lastname: Gao
authors.forename: Shulin
authors.initials: S
authors.lastname: Chen
mesh_terms: D050260:Carbohydrate Metabolism / Q000502:physiology*; D008031:Lignin / Q000378:metabolism*; D008055:Lipids / Q000096:biosynthesis*; D020094:Mortierella / Q000378:metabolism*
chemical_list: D008055:Lipids; C036909:lignocellulose; D008031:Lignin