title: Presence and bioaccumulation of microcystins and cylindrospermopsin in food and the effectiveness of some cooking techniques at decreasing their concentrations: a review.
abstract: Microcystins (MCs) and cylindrospermopsin (CYN) are among the cyanotoxins which occur naturally, produced by different cyanobacteria species when they grow or proliferate under favorable environmental conditions. From a toxicological point of view, their relevance is due to the deleterious effects that they have been reported to induce in a wide range of organisms, including humans. Cyanotoxins intake from contaminated water and food is an important source of human exposure. Various edible aquatic organisms, plants, and food supplements based on algae, can bioaccumulate these toxins. A thorough review of the scientific data available on this topic is provided, the studies on MCs being much more numerous than those focused on CYN. The scientific literature suggests that these cyanotoxins can be accumulated at concentrations higher than their respective recommended tolerable daily intake (TDI). Finally, the influence of different cooking procedures on their levels in food has been considered. In this regard, again studies on the matter dealing with CYN have been not yet raised. MCs contents have been reported to be reduced in muscle of fish after boiling, or cooking in a microwave-oven, although the effect of other traditional cooking processes such as frying, roasting or grilling have not been demonstrated.
authors.affiliation: Nutrición y Bromatología, Toxicología y Medicina Legal Department, Faculty of Pharmacy, University of Sevilla, C/Profesor García González 2, 41012 Sevilla, Spain.
authors.forename: Daniel
authors.initials: D
authors.lastname: Gutiérrez-Praena
authors.forename: Ángeles
authors.initials: Á
authors.lastname: Jos
authors.forename: Silvia
authors.initials: S
authors.lastname: Pichardo
authors.forename: Isabel M
authors.initials: IM
authors.lastname: Moreno
authors.forename: Ana M
authors.initials: AM
authors.lastname: Cameán
mesh_terms: D000470:Alkaloids; D000818:Animals; D001427:Bacterial Toxins; D003257:Consumer Product Safety; D003296:Cooking / Q000379:methods*; D000458:Cyanobacteria / Q000378:metabolism; D000087522:Cyanobacteria Toxins; D005399:Fishes / Q000382:microbiology; D005506:Food Contamination / Q000032:analysis*; D005516:Food Microbiology; D008387:Marine Toxins / Q000032:analysis / Q000737:chemistry; D052998:Microcystins / Q000032:analysis* / Q000737:chemistry; D014498:Uracil / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry
chemical_list: D000470:Alkaloids; D001427:Bacterial Toxins; D000087522:Cyanobacteria Toxins; D008387:Marine Toxins; D052998:Microcystins; C089595:cylindrospermopsin; D014498:Uracil