title: Photoselective vaporization of prostate vs. transurethral resection of prostate: A prospective, randomized study with one year follow-up.
abstract: OBJECTIVE
  To evaluate in a prospective, randomized study, the efficacy and safety profile of photoselective vaporization of prostate (PVP) using a 80W potassium titanyl phosphate (KTP) laser when compared to standard transurethral resection of prostate (TURP) in patients with lower urinary tract symptoms (LUTS) due to benign prostatic enlargement (BPE).
  
  
  METHODS
  Between February 2009 and August 2009, 117 patients satisfying the eligibility criteria underwent surgery [60 PVP{Group A}; 57 TURP{Group B}]. The groups were compared for functional outcome (both subjective and objective parameters), perioperative parameters and complications, with a follow up of one year. P value<0.05 was considered statistically significant.
  
  
  RESULTS
  The baseline characteristics of the two groups were comparable. Mean age was 66.68 years and 65.74 years, mean IPSS score was 19.98 and 20.88, mean prostate volume was 44.77 cc and 49.02 cc in Group A and B, respectively. Improvements in IPSS, QOL, prostate volume, Q max and PVRU at 12 months were similar in both groups. PVP patients had longer operating time, lesser perioperative blood loss, shorter catheterization time and a higher dysuria rate when compared to TURP patients. The overall complication rate was similar in the two groups.
  
  
  CONCLUSIONS
  In patients with LUTS due to BPE, KTP-PVP is an equally efficacious alternative to TURP with durable results at one year follow up with additional benefits of lesser perioperative blood loss, lesser transfusion requirements and a shorter catheterization time. Long term comparative data is awaited to clearly define the role of KTP-PVP in such patients.
authors.affiliation: Department of Urology, V.M. Medical College and Safdarjang Hospital, New Delhi, India.
authors.forename: Nayan K
authors.initials: NK
authors.lastname: Mohanty
authors.forename: Pawan
authors.initials: P
authors.lastname: Vasudeva
authors.forename: Anup
authors.initials: A
authors.lastname: Kumar
authors.forename: Sanjay
authors.initials: S
authors.lastname: Prakash
authors.forename: Manoj
authors.initials: M
authors.lastname: Jain
authors.forename: Rajender P
authors.initials: RP
authors.lastname: Arora