title: Defective spatial control in patterning of microtubular structures in mutants of the ciliate Paraurostyla: II. Spatial coordinates in a double recessive mutant.
abstract: The abnormal ciliary pattern and its propagation was studied in the double recessive mutant 95 (mlm/mlm, pl/pl) in Paraurostyla weissei. In line 95, widening and concomitant overlapping of three organelle domains occurs at the right ventro-lateral part of the cell, in addition to the multi-left-marginal syndrome involving broadening of three organellar domains in the left ventro-lateral part of the cell (Dubielecka and Jerka-Dziadosz 1989). The modifications in positioning of ciliary primordia pervade both left and right parts of the cell, suggesting that the cell's ability to maintain discrete boundary conditions is affected. The way in which particular primordia of ciliature develop is consistent with an intercalation-overlapping model that postulates a cyclic instability of the system of positional information caused by a change in distribution of the ventral positional values and intercalation of intermediate values at the lateral parts of the cell. The developmental phenotype is a result of the ability of the morphogenetic machinery of the cell to record different phases of the postulated positional cycle.
authors.affiliation: Department of Cell Biology, M. Nencki Institute of Experimental Biology, Warsaw, Poland; Zoological Institute of Westfalian University, Münster, FRG.
authors.forename: M
authors.initials: M
authors.lastname: Jerka-Dziadosz