title: [Quantifying the amplitude of microvolt T wave alternans with sparse principal component analysis].
abstract: T wave alternans in ECG is an important prediction factor for a sudden death. It is crucial in clinic to quantify the amplitude of T wave alternans. However, T wave alternans are highly non-stationary, which makes accurate quantification very difficult. In this study, we proposed a new method to improve the amplitude quantification. We identified T wave alternans by principal component analysis (PCA) with statistical test, and processed the principal components with T wave alternans further by imposing sparse constraint. We evaluated and compared our method against other 4 popular solutions on an international benchmark database. The results including rank correlation coefficient and relative error indicate that this sparse principal component (SPC) based method is better than others.
authors.affiliation: School of Automation, Wuhan University of Technology, Wuhan 430070, China. xkarcher@126.com
authors.forename: Kui
authors.initials: K
authors.lastname: Xiang
authors.forename: Bingnan
authors.initials: B
authors.lastname: Li
mesh_terms: D000465:Algorithms; D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000503:physiopathology*; D016757:Death, Sudden, Cardiac / Q000517:prevention & control*; D004562:Electrocardiography / Q000379:methods*; D006801:Humans; D025341:Principal Component Analysis; D012815:Signal Processing, Computer-Assisted