title: Demographics and epidemiology of pancreatic cancer.
abstract: Pancreatic cancer affects 44,000 Americans and at least 250,000 individuals worldwide annually. The incidence is slowly increasing after a recent period of decline. Cases are predicted to increase globally because of increased longevity and the widespread adoption of cancer-causing behaviors, such as cigarette smoking, dietary indiscretion, and a global increase in diabetes. Well-known risk factors for pancreatic cancer are advancing age, tobacco smoking, obesity, certain inherited familial disorders, second-hand smoke exposure, chronic pancreatitis, and diabetes. Associations with human immunodeficiency virus, ABO blood group, hepatitis B virus, human immunodeficiency virus, and Helicobacter pylori have also been identified.
authors.affiliation: Thomas Jefferson University, Jefferson School of Nursing, Philadelphia, PA, USA. theresa.yeo@jefferson.edu
authors.forename: Theresa Pluth
authors.initials: TP
authors.lastname: Yeo
authors.forename: Albert B
authors.initials: AB
authors.lastname: Lowenfels
mesh_terms: D021441:Carcinoma, Pancreatic Ductal / Q000453:epidemiology / Q000235:genetics / Q000401:mortality; D003710:Demography; D020022:Genetic Predisposition to Disease; D014943:Global Health; D006801:Humans; D015994:Incidence; D010190:Pancreatic Neoplasms / Q000453:epidemiology* / Q000235:genetics / Q000401:mortality; D012307:Risk Factors