title: Prostate cancer may trigger paraneoplastic limbic encephalitis: a case report and a review of the literature.
abstract: We present a case of a previously healthy and active 64-year-old man who experienced a rapid neuropsychiatric decline. All tests for metabolic causes, neuroinfection, intracranial infarction or tumor were negative. By the means of magnetic resonance imaging, electroencephalography and the anti-Hu antibody test the patient was diagnosed with paraneoplastic limbic encephalitis related to prostate cancer. The patient died within 6 months. We review the literature on prostate cancer-related paraneoplastic limbic encephalitis. High-risk prostate cancer can trigger paraneoplastic limbic encephalitis, a rapidly progressive neurological syndrome with a bad prognosis.
authors.affiliation: Department of Urology, Viborg Hospital, Viborg, Denmark.
authors.forename: Jakob Kristian
authors.initials: JK
authors.lastname: Jakobsen
authors.forename: Elias Raja
authors.initials: ER
authors.lastname: Zakharia
authors.forename: Anders Kindberg
authors.initials: AK
authors.lastname: Boysen
authors.forename: Henning
authors.initials: H
authors.lastname: Andersen
authors.forename: Friedrich Emanuel
authors.initials: FE
authors.lastname: Schlesinger
authors.forename: Lars
authors.initials: L
authors.lastname: Lund
mesh_terms: D017809:Fatal Outcome; D006801:Humans; D020363:Limbic Encephalitis / Q000209:etiology* / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000150:complications*