title: [Hypoclycaemia in a diabetic man's wife].
abstract: Insulinoma are rare tumours with an incidence of 4/100'000, supposedly hypoglycaemic symptoms, however, are often attributed to people without diabetes mellitus. The many different causes of hypoglycaemic disorders are best classified in whether occurring in healthy-appearing or ill patients. Patient's history and physical examination allow to substantiate the suspected hyperinsulinaemic hypoglycaemia which need to be proven in the 72-hour fast to meet the Whipple triad, i. e. low plasma glucose <= 2.5 mmol/l and neuroglycopenic symptoms and relief after ingesting glucose. In the next step localisation of the suspected insulinoma and exclusion of non-insulinoma pancreatogenous hypoglycaemia is aimed at. GLP-1 receptor scintigraphy, a recent and sensitive method to localize insulinoma, proved reliable in the presented case report.
authors.affiliation: Departement Medizin, Luzerner Kantonsspital, Luzern. christoph.henzen@luks.ch
authors.forename: C
authors.initials: C
authors.lastname: Henzen
mesh_terms: D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005215:Fasting / Q000097:blood; D005260:Female; D006801:Humans; D006946:Hyperinsulinism / Q000097:blood / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D007003:Hypoglycemia / Q000097:blood / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D007340:Insulinoma / Q000097:blood / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008297:Male; D010179:Pancreas / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D018454:Spouses
chemical_list: D001786:Blood Glucose