title: A 48-month clinical evaluation of fissure sealants placed with different adhesive systems.
abstract: OBJECTIVE
  To compare the retention rates of a nanofilled occlusal fissure sealant placed with the use of an etch-and-rinse or a self-etch adhesive over 48 months.
  
  
  METHODS
  The authors enrolled 244 teeth, each with no restoration or sealant and no detectable caries, from 16 patients. The sealants were placed with Solobond M two-step etch-and-rinse adhesive or Futurabond NR one-step self-etch adhesive by four previously calibrated dentists using a table of random numbers. After completion of the adhesive application, a nanofilled sealant, Grandio Seal, was applied and light-cured. Two other calibrated examiners, who were unaware of which adhesive had been used, independently evaluated the sealants at baseline and at 12-, 24-, 36-, and 48-month recalls. Each sealant was evaluated in terms of caries formation being present or absent and retention using the following criteria: 1 = completely retained, 2 = partial loss, and 3 = total loss. The Pearson χ (2) test was used to evaluate differences in retention rates among the sealants used with different adhesives for each evaluation period.
  
  
  RESULTS
  The retention rates for sealants in the Solobond M group were significantly higher than those in the Futurabond NR group in all periods of evaluation (p<0.05). No statistically significant difference between the retention rates for premolars and molars was found at each evaluation period (p>0.05). There was no new caries formation throughout the 48-month recall period.
  
  
  CONCLUSIONS
  Fissure sealants placed with etch-and-rinse adhesive showed better retention rates than those placed with self-etch adhesive.
authors.affiliation: Faculty of Dentistry, Department of Restorative Dentistry, Ondokuz Mayıs University, Kurupelit, Samsun, Turkey.
authors.forename: E
authors.initials: E
authors.lastname: Karaman
authors.forename: A R
authors.initials: AR
authors.lastname: Yazici
authors.forename: D
authors.initials: D
authors.lastname: Tuncer
authors.forename: E
authors.initials: E
authors.lastname: Firat
authors.forename: S
authors.initials: S
authors.lastname: Unluer
authors.forename: M
authors.initials: M
authors.lastname: Baseren
mesh_terms: D000293:Adolescent; D001641:Bicuspid / Q000473:pathology; D003188:Composite Resins / Q000737:chemistry; D001840:Dental Bonding / Q000379:methods*; D003731:Dental Caries / Q000517:prevention & control; D003743:Dental Enamel / Q000473:pathology; D017220:Dentin-Bonding Agents / Q000737:chemistry; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D055115:Light-Curing of Dental Adhesives / Q000379:methods; D008297:Male; D008689:Methacrylates / Q000737:chemistry; D008963:Molar / Q000473:pathology; D053761:Nanocomposites / Q000737:chemistry; D010895:Pit and Fissure Sealants / Q000737:chemistry* / Q000627:therapeutic use; D013499:Surface Properties; D055815:Young Adult
chemical_list: D003188:Composite Resins; D017220:Dentin-Bonding Agents; C509998:Grandio; D008689:Methacrylates; D010895:Pit and Fissure Sealants; C425825:Solobond M; C512545:futurabond NR