title: The presence of D-fagomine in the human diet from buckwheat-based foodstuffs.
abstract: Buckwheat (Fagopyrum esculentum Moench) groats contain the iminosugar D-fagomine as a minor component that might contribute to the alleged health benefits of this pseudo-cereal. This study presents analysis of D-fagomine in buckwheat-based foodstuffs by liquid chromatography coupled to mass spectrometry and an estimation of its presence in the human diet based on a published population-based cross-sectional nutrition survey. D-fagomine is present in common buckwheat-based foodstuffs in amounts ranging from 1 to 25 mg/kg or mg/L, it is stable during boiling, baking, frying and fermentation, and it is biosynthesised upon sprouting. The estimated total intake of D-fagomine resulting from a diet that includes such foodstuffs would be between 3 and 17 mg per day (mean for both genders; range from P5 to P95). A diet rich in buckwheat products would provide a daily amount of D-fagomine that may in part explain the beneficial properties traditionally attributed to buckwheat consumption.
authors.affiliation: Bioglane SLNE, Tavern 17, 08006 Barcelona, Spain.
authors.forename: Susana
authors.initials: S
authors.lastname: Amézqueta
authors.forename: Esther
authors.initials: E
authors.lastname: Galán
authors.forename: Ingrid
authors.initials: I
authors.lastname: Vila-Fernández
authors.forename: Sergio
authors.initials: S
authors.lastname: Pumarola
authors.forename: Montserrat
authors.initials: M
authors.lastname: Carrascal
authors.forename: Joaquin
authors.initials: J
authors.lastname: Abian
authors.forename: Lourdes
authors.initials: L
authors.lastname: Ribas-Barba
authors.forename: Lluís
authors.initials: L
authors.lastname: Serra-Majem
authors.forename: Josep Lluís
authors.initials: JL
authors.lastname: Torres
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003430:Cross-Sectional Studies; D004032:Diet; D019612:Fagopyrum / Q000737:chemistry* / Q000378:metabolism; D005260:Female; D006801:Humans; D050112:Imino Pyranoses / Q000032:analysis* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009753:Nutritive Value; D055815:Young Adult
chemical_list: D050112:Imino Pyranoses; C105643:fagomine