title: Targeted isotretinoin in neuroblastoma: kinetics, genetics, or absorption.
abstract: Isotretinoin (13-cis-retinoic acid; 13-cisRA) has been shown to significantly improve survival for children with high-risk neuroblastoma. Pharmacokinetics of isotretinoin may be negatively affected by the mode of drug administration and the dosing formula.
authors.affiliation: Department of Pediatrics and Helen Diller Family Comprehensive Cancer Center, School of Medicine, University of California-San Francisco, CA 94143, USA. matthayk@peds.ucsf.edu
authors.forename: Katherine K
authors.initials: KK
authors.lastname: Matthay
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage*; D008297:Male; D009447:Neuroblastoma / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents; D015474:Isotretinoin