title: Chronic granulomatous mastitis: Imaging, pathology and management.
abstract: OBJECTIVE
  The aim of this study is to describe the clinical and radiological presentation of chronic granulomatous mastitis.
  
  
  METHODS
  We retrospectively reviewed the clinical and radiological data of 11 women with histologically proven chronic granulomatous mastitis (CGM) diagnosed between March 2008 and September 2011.
  
  
  RESULTS
  The diagnosis of CGM is often a challenging one that can mimic infectious and malignant breast conditions. Clinically, CGM most commonly presents as a mass, occasionally with associated erythema. The most frequent mammographic presentation is an asymmetric density, while ultrasound most commonly reveals a hypoechoic mass with tubular extensions and a striated echotexture. On MRI, the most specific finding is peripherally enhancing fluid or solid masses with fistulous tract to the skin, although the latter is not commonly encountered. Diagnosis can be reliably obtained by needle core or vacuum-assisted biopsy, and is established pathologically by the identification of granulomatous inflammation without caseous necrosis. CGM is a diagnosis of exclusion after infectious and foreign body causes are ruled out. Treatment options include oral steroids or surgery; both options are associated with similar recurrence rates. The disease tends to burn itself out and the option of conservative management with observation is a valid one.
  
  
  CONCLUSIONS
  CGM is a rare benign disease with no specific features clinically or at imaging. There are no radiologic findings that are specific of CGM, but in the appropriate clinical setting, the diagnosis can be suggested by the radiologist.
authors.affiliation: Centre Régional de Lutte Contre le Cancer Eugène Marquis, avenue Bataille Flandres Dunkerque, Rennes, France. nsgautier@yahoo.fr
authors.forename: Nicolas
authors.initials: N
authors.lastname: Gautier
authors.forename: Lucie
authors.initials: L
authors.lastname: Lalonde
authors.forename: Danh
authors.initials: D
authors.lastname: Tran-Thanh
authors.forename: Mona
authors.initials: M
authors.lastname: El Khoury
authors.forename: Julie
authors.initials: J
authors.lastname: David
authors.forename: Maude
authors.initials: M
authors.lastname: Labelle
authors.forename: Erica
authors.initials: E
authors.lastname: Patocskai
authors.forename: Isabelle
authors.initials: I
authors.lastname: Trop
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D058890:Granulomatous Mastitis / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008327:Mammography; D008875:Middle Aged; D012008:Recurrence; D016217:Ultrasonography, Mammary