title: Edith Lincoln, an American pioneer of childhood tuberculosis.
abstract: Edith Lincoln (1899-1971), one of the most influential American pediatricians to study childhood tuberculosis, managed more than a thousand children from time of tuberculosis infection into adult life. She spoke with authority regarding the prognosis of childhood tuberculosis. Her observations of chemotherapy in children treated with isoniazid led directly to chemoprophylaxis, now of great importance in the management of the human immunodeficiency syndrome.
authors.affiliation: Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa. prd@sun.ac.za
authors.forename: Peter R
authors.initials: PR
authors.lastname: Donald
mesh_terms: D000293:Adolescent; D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D049673:History, 20th Century; D006801:Humans; D007223:Infant; D055552:Infectious Disease Medicine / Q000266:history*; D008297:Male; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy*; D014481:United States; D055815:Young Adult
chemical_list: D000995:Antitubercular Agents