title: A luminescent G-quadruplex switch-on probe for the highly selective and tunable detection of cysteine and glutathione.
abstract: A G-quadruplex-selective luminescent iridium(III) switch-on probe has been developed for the detection of cysteine (Cys) in aqueous solution. The system is highly sensitive and selective towards Cys with a tunable range of detection. The detection of glutathione (GSH) is also examined.
authors.affiliation: Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, China.
authors.forename: Ka-Ho
authors.initials: KH
authors.lastname: Leung
authors.forename: Hong-Zhang
authors.initials: HZ
authors.lastname: He
authors.forename: Victor Pui-Yan
authors.initials: VP
authors.lastname: Ma
authors.forename: Daniel Shiu-Hin
authors.initials: DS
authors.lastname: Chan
authors.forename: Chung-Hang
authors.initials: CH
authors.lastname: Leung
authors.forename: Dik-Lung
authors.initials: DL
authors.lastname: Ma
mesh_terms: D056831:Coordination Complexes / Q000737:chemistry; D003545:Cysteine / Q000032:analysis*; D004247:DNA / Q000737:chemistry*; D054856:G-Quadruplexes; D005978:Glutathione / Q000032:analysis*; D007495:Iridium / Q000737:chemistry*; D049408:Luminescent Agents / Q000737:chemistry*; D008163:Luminescent Measurements / Q000379:methods; D012680:Sensitivity and Specificity
chemical_list: D056831:Coordination Complexes; D049408:Luminescent Agents; D007495:Iridium; D004247:DNA; D005978:Glutathione; D003545:Cysteine