title: Spontaneous pneumomediastinum caused by bleomycin-induced pneumonitis.
abstract: We report the case of a 24-yr-old woman treated for lymphoma who developed bleomycin-induced interstitial pneumonia. This interstitial pneumonia was complicated by spontaneous pneumomediastinum. Pneumomediastinum is an unfrequent side effect of high dose bleomycin-induced pneumonitis (BIP) and we describe the first case occurring with low-dose of bleomycin.
authors.affiliation: Departement of Pneumology, CHU Sart Tilman B35, Liège, Belgium. fruschnicolas@hotmail.com
authors.forename: N
authors.initials: N
authors.lastname: Frusch
authors.forename: S
authors.initials: S
authors.lastname: Servais
authors.forename: B
authors.initials: B
authors.lastname: De Prijck
authors.forename: J L
authors.initials: JL
authors.lastname: Corhay
authors.forename: Y
authors.initials: Y
authors.lastname: Beguin
authors.forename: R
authors.initials: R
authors.lastname: Louis
authors.forename: B
authors.initials: B
authors.lastname: Duysinx
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000009:adverse effects / Q000627:therapeutic use; D001706:Biopsy; D001761:Bleomycin / Q000009:adverse effects* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000175:diagnosis / Q000188:drug therapy*; D008478:Mediastinal Emphysema / Q000175:diagnosis / Q000209:etiology*; D011014:Pneumonia / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D055815:Young Adult
chemical_list: D000903:Antibiotics, Antineoplastic; D001761:Bleomycin