title: [A case of mediastinal angiosarcoma].
abstract: BACKGROUND
  Mediastinal angiosarcoma is a rare intrathoracic tumour and the therapeutic approach remains poorly codified.
  
  
  METHODS
  We report the case of a 65-year-old female patient presenting with chest pain. Further exploration revealed an anterior mediastinal mass with pericardial invasion. Transthoracic biopsy gave the diagnosis of angiosarcoma. Multimodal treatment with neoadjuvant chemotherapy (doxorubicin 20 mg/m(2), Ifosfamide 2500 mg/m(2), Uromitexan® 2500 mg/m(2)) and surgery followed by adjuvant radiotherapy has led to remission of the tumour that has persisted for 12 months.
  
  
  CONCLUSIONS
  Systematic recording of such conditions in dedicated registries could contribute to enhance the description of the clinical and pathological characteristics, thus helping define the principles of specific management.
authors.affiliation: PCMAC, unité d'oncologie thoracique, CHU de Grenoble, Grenoble cedex, France. aderoux@chu-grenoble.fr
authors.forename: A
authors.initials: A
authors.lastname: Deroux
authors.forename: M
authors.initials: M
authors.lastname: Destors
authors.forename: M
authors.initials: M
authors.lastname: Coudurier
authors.forename: S
authors.initials: S
authors.lastname: Lantuejoul
authors.forename: M
authors.initials: M
authors.lastname: Aubert
authors.forename: N
authors.initials: N
authors.lastname: Girard
authors.forename: D
authors.initials: D
authors.lastname: Moro-Sibilot
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D002637:Chest Pain / Q000209:etiology; D004317:Doxorubicin / Q000008:administration & dosage; D004417:Dyspnea / Q000209:etiology; D005260:Female; D006394:Hemangiosarcoma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008279:Magnetic Resonance Imaging; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D015080:Mesna / Q000008:administration & dosage; D020360:Neoadjuvant Therapy; D009361:Neoplasm Invasiveness; D049268:Positron-Emission Tomography; D018714:Radiotherapy, Adjuvant; D012074:Remission Induction; D013616:Tachycardia, Sinus / Q000150:complications / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D015431:Weight Loss
chemical_list: D004317:Doxorubicin; D015080:Mesna; D007069:Ifosfamide