title: Organocatalytic tandem Michael addition reactions: A powerful access to the enantioselective synthesis of functionalized chromenes, thiochromenes and 1,2-dihydroquinolines.
abstract: Enantioselective organocatalysis has become a field of central importance within asymmetric chemical synthesis and appears to be efficient approach toward the construction of complex chiral molecules from simple achiral materials in one-pot transformations under mild conditions with high stereocontrol. This review addresses the most significant synthetic methods reported on chiral-amine-catalyzed tandem Michael conjugate addition of heteroatom-centered nucleophiles to α,β-unsaturated compounds followed by cyclization reactions for the enantioselective construction of functionalized chiral chromenes, thiochromenes and 1,2-dihydroquinolines in optically enriched forms found in a myriad of bioactive natural products and synthetic compounds.
authors.affiliation: Department of Chemistry, Utkal University, Bhubaneswar-751 004, Odisha, India.
authors.forename: Chittaranjan
authors.initials: C
authors.lastname: Bhanja
authors.forename: Satyaban
authors.initials: S
authors.lastname: Jena
authors.forename: Sabita
authors.initials: S
authors.lastname: Nayak
authors.forename: Seetaram
authors.initials: S
authors.lastname: Mohapatra