title: Histopathology of vascular anomalies.
abstract: Vascular anomalies may be appropriately classified into two broad categories, vascular tumors and vascular malformations, which are distinguished by the presence of cellular proliferation in contrast to aberrations in morphogenesis, respectively. This system of classification is based upon histological features that may in large part be differentiating, but nevertheless, may show morphological overlap. Advances in immunophenotyping allow for more precise diagnoses as well as further delineation of cell origins. In the discussion, we present the clinical, histological, and, when applicable, the immunophenotypic presentation of vascular anomalies commonly seen in infancy and early childhood.
authors.affiliation: Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02115, USA.
authors.forename: Amir
authors.initials: A
authors.lastname: Aboutalebi
authors.forename: Chad J
authors.initials: CJ
authors.lastname: Jessup
authors.forename: Paula E
authors.initials: PE
authors.lastname: North
authors.forename: Martin C
authors.initials: MC
authors.lastname: Mihm
mesh_terms: D001165:Arteriovenous Malformations / Q000473:pathology; D006390:Hemangioendothelioma / Q000473:pathology; D006391:Hemangioma / Q000145:classification / Q000151:congenital* / Q000473:pathology*; D006801:Humans; D059885:Kasabach-Merritt Syndrome / Q000473:pathology; D044148:Lymphatic Abnormalities / Q000145:classification / Q000473:pathology*; D012514:Sarcoma, Kaposi / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology; D009626:Terminology as Topic; D054079:Vascular Malformations / Q000145:classification / Q000473:pathology*