title: [Principles of glucocorticoid therapy].
abstract: The principles of systemic glucocorticoid (GC) therapy in dermatology are reviewed. As a basis for an efficient GC therapy with few side effects the pharmacology, endogenous regulation as well as the mechanisms and side effects of GCs as well as their management are introduced. Modern therapeutic approaches such as circadian application and low-dose therapy are discussed as well as principles of tapering dosages and the most important indications for systemic GCs in dermatology.
authors.affiliation: Klinik für Hautkrankheiten - Allgemeine Dermatologie und Venerologie, Universitätsklinikum Münster, Von-Esmarch Str. 58, 48149, Münster, Deutschland. jan.ehrchen@ukmuenster.de
authors.forename: J
authors.initials: J
authors.lastname: Ehrchen
mesh_terms: D000293:Adolescent; D000309:Adrenal Insufficiency / Q000139:chemically induced / Q000517:prevention & control; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D055870:Drug Chronotherapy; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007273:Injections, Intramuscular; D011247:Pregnancy; D020551:Pulse Therapy, Drug; D012871:Skin Diseases / Q000097:blood / Q000188:drug therapy*
chemical_list: D005938:Glucocorticoids