title: Solvent-assisted dispersive micro-SPE by using aminopropyl-functionalized magnetite nanoparticle followed by GC-PID for quantification of parabens in aqueous matrices.
abstract: In this research, solvent-assisted dispersive micro-SPE was introduced as a simple modified technique for the determination of parabens in water and cosmetic samples. Aminopropyl-functionalized magnetite nanoparticles (MNPs) were successfully synthesized and applied. GC with photoionization detector was used for the separation and detection of parabens. In this method, hexylacetate (15 μL) as a solvent and aminopropyl-functionalized MNPs (5 μg) as a sorbent were added to an aqueous sample (10 mL) and then the sample was sonicated. Dispersed magnetite was collected in the bottom of the conical tube by using a strong magnet and then ACN was added as a desorption solvent. Forty microliters of this solvent was transferred into a microvial and then acetic anhydride and pyridine were added, thus derivatization was performed by acetic anhydride. After evaporation, 1 μL of derivatized sample was injected into a gas chromatograph for analysis. Several important parameters, such as kind of organic solvent, desorption solvent and volume, amount of aminopropyl-functionalized MNPs and effect of salt addition were investigated. Under optimum conditions, the limits of detection achieved were between 50 and 300 ng/L, with RSDs (n = 5) lower than 8%. Under the optimum conditions, the enrichment factors ranged from 217 to 1253 and the extraction recoveries ranged from 10 to 62%. The recoveries were obtained for the analytes in river water and mouthwash solution and hand cream in the range of 87-103%. The advantages of proposed method are simplicity of operation, rapidity, high extraction yields, and environmental friendly character.
authors.affiliation: Department of Chemistry, Payame Noor University, Mashhad, Iran. aghorbani2003@yahoo.com
authors.forename: Maryam
authors.initials: M
authors.lastname: Abbasghorbani
authors.forename: Abdolmohammad
authors.initials: A
authors.lastname: Attaran
authors.forename: Mahmood
authors.initials: M
authors.lastname: Payehghadr
mesh_terms: D000327:Adsorption; D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000302:isolation & purification*; D002849:Chromatography, Gas / Q000295:instrumentation / Q000379:methods*; D058185:Magnetite Nanoparticles / Q000737:chemistry; D010226:Parabens / Q000032:analysis* / Q000302:isolation & purification*; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000032:analysis* / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents; D058185:Magnetite Nanoparticles; D010226:Parabens; D014874:Water Pollutants, Chemical