title: Flow-injection analysis systems with different detection devices and other related techniques for the in vitro and in vivo determination of dopamine as neurotransmitter. A review.
abstract: Dopamine (DA) is one of the most important catecholamine neurotransmitters in the human central nervous system in the brain and plays a key role in the functioning of the renal, hormonal, and cardiovascular systems. Abnormal levels of dopamine are related to neurological disorders, such as schizophrenia and Parkinson's disease and the control and fluctuations of the amount of dopamine are extremely important in monitoring with analytical systems in the human brain. This review covers the attributes of flow-injection analysis systems with different detection devices and other related techniques for the in vitro and in vivo determination of dopamine as neurotransmitter and points out the advantages and disadvantages in the implementation thereof.
authors.affiliation: Process Analytical Technology Laboratory (PATLAB), National Institute of Research and Development for Electrochemistry and Condensed Matter (INCDEMC), 202 Splaiul Independentei Str., Bucharest 060021, Romania. koosvanstaden@yahoo.com
authors.forename: Jacobus F
authors.initials: JF
authors.lastname: van Staden
authors.forename: Raluca I Stefan
authors.initials: RI
authors.lastname: van Staden
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004298:Dopamine / Q000032:analysis*; D017022:Flow Injection Analysis; D006801:Humans; D017736:Ion-Selective Electrodes; D049449:Luminescence; D044085:Microfluidics; D013053:Spectrophotometry
chemical_list: D004298:Dopamine