title: Clinical implication of mechanical dyssynchrony in heart failure.
abstract: Mechanical dyssynchrony is a common phenomenon in patients with congestive heart failure, which usually identified by noninvasive cardiac imaging tools such as echocardiography. It demonstrates electromechanical delay in some regions of the failing heart which in turn contributes to further impairment of cardiac function. The diagnostic, therapeutic and prognostic values of mechanical dyssynchrony have been reported in a number of studies. Therefore, this review describes briefly the methods of measurement, but more importantly, explains the clinical implication of its assessment in heart failure related aspects including cardiac resynchronization therapy, functional mitral regurgitation, diastolic heart failure and mortality.
authors.affiliation: Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China. ; Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhang
authors.forename: Cheuk-Man
authors.initials: CM
authors.lastname: Yu