title: Recent approaches for C-C bond formation via direct dehydrative coupling strategies.
abstract: In recent years, reaction of inexpensive and abundantly available alcohols (C-OH) with unactivated nucleophilic coupling partners (C-H), leading to the construction of the C-C bond, has emerged as one of the vital strategies since it is an atom-economical and environmentally benign approach with water as the by-product. Various transition metal-catalyzed or metal-free approaches for the direct dehydrative coupling employing the C-OH bond (including in situ activation) have recently been devised. This review article aims to highlight advances in such waste-free C-C bond forming dehydrative strategies.
authors.affiliation: Laboratory for Organic & Microwave-Assisted Chemistry, (LOMAC), Department of Chemistry, University of Leuven (KU Leuven), Celestijnenlaan 200F, B-3001, Leuven, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Kumar
authors.forename: E V
authors.initials: EV
authors.lastname: Van der Eycken
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic / Q000379:methods*; D008670:Metals / Q000737:chemistry; D015394:Molecular Structure; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000438:Alcohols; D008670:Metals; D009930:Organic Chemicals