title: Endobronchial involvement in non-Hodgkin lymphoma.
abstract: Non-Hodgkin lymphoma generally affects the thorax in nearly half of the cases, but endobronchial non-Hodgkin lymphoma is rare. A 65-year-old man presented with refractory cough and progressive dyspnea on exertion of 2 months' duration. The patient denied fever, weight loss, or night sweats. A chest x-ray revealed bilateral lower lobe infiltrates. A computed tomography scan of the chest revealed large matted mediastinal lymph nodes without clear margination. Bronchoscopic examination revealed bilateral endobronchial diffuse nodular lesions. Bronchial mucosal biopsy demonstrated B-cell lymphoma. The patient was treated with R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone) regimen with near-total resolution of endobronchial and parenchymal lesions.
authors.affiliation: Department of Chest Diseases, Ankara Atatürk Training and Research Hospital, Bilkent Street, Ankara, Turkey. drgullu2000@gmail.com
authors.forename: Emine
authors.initials: E
authors.lastname: Argüder
authors.forename: Hatice Canan
authors.initials: HC
authors.lastname: Hasanoğlu
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Karalezli
authors.forename: Sema
authors.initials: S
authors.lastname: Aknc
authors.forename: Imdat
authors.initials: I
authors.lastname: Dilek
mesh_terms: D000368:Aged; D000402:Airway Obstruction / Q000209:etiology; D058846:Antibodies, Monoclonal, Murine-Derived / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D001984:Bronchial Neoplasms / Q000175:diagnosis / Q000188:drug therapy*; D001999:Bronchoscopy; D003520:Cyclophosphamide / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D011241:Prednisone / Q000008:administration & dosage; D000069283:Rituximab; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; C571759:R-CHOP protocol; D000069283:Rituximab; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone