title: Facing growth in the European Nucleotide Archive.
abstract: The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena/) collects, maintains and presents comprehensive nucleic acid sequence and related information as part of the permanent public scientific record. Here, we provide brief updates on ENA content developments and major service enhancements in 2012 and describe in more detail two important areas of development and policy that are driven by ongoing growth in sequencing technologies. First, we describe the ENA data warehouse, a resource for which we provide a programmatic entry point to integrated content across the breadth of ENA. Second, we detail our plans for the deployment of CRAM data compression technology in ENA.
authors.affiliation: EMBL - European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. cochrane@ebi.ac.uk
authors.forename: Guy
authors.initials: G
authors.lastname: Cochrane
authors.forename: Blaise
authors.initials: B
authors.lastname: Alako
authors.forename: Clara
authors.initials: C
authors.lastname: Amid
authors.forename: Lawrence
authors.initials: L
authors.lastname: Bower
authors.forename: Ana
authors.initials: A
authors.lastname: Cerdeño-Tárraga
authors.forename: Iain
authors.initials: I
authors.lastname: Cleland
authors.forename: Richard
authors.initials: R
authors.lastname: Gibson
authors.forename: Neil
authors.initials: N
authors.lastname: Goodgame
authors.forename: Mikyung
authors.initials: M
authors.lastname: Jang
authors.forename: Simon
authors.initials: S
authors.lastname: Kay
authors.forename: Rasko
authors.initials: R
authors.lastname: Leinonen
authors.forename: Xiu
authors.initials: X
authors.lastname: Lin
authors.forename: Rodrigo
authors.initials: R
authors.lastname: Lopez
authors.forename: Hamish
authors.initials: H
authors.lastname: McWilliam
authors.forename: Arnaud
authors.initials: A
authors.lastname: Oisel
authors.forename: Nima
authors.initials: N
authors.lastname: Pakseresht
authors.forename: Swapna
authors.initials: S
authors.lastname: Pallreddy
authors.forename: Youngmi
authors.initials: Y
authors.lastname: Park
authors.forename: Sheila
authors.initials: S
authors.lastname: Plaister
authors.forename: Rajesh
authors.initials: R
authors.lastname: Radhakrishnan
authors.forename: Stephane
authors.initials: S
authors.lastname: Rivière
authors.forename: Marc
authors.initials: M
authors.lastname: Rossello
authors.forename: Alexander
authors.initials: A
authors.lastname: Senf
authors.forename: Nicole
authors.initials: N
authors.lastname: Silvester
authors.forename: Dmitriy
authors.initials: D
authors.lastname: Smirnov
authors.forename: Petra
authors.initials: P
authors.lastname: Ten Hoopen
authors.forename: Ana
authors.initials: A
authors.lastname: Toribio
authors.forename: Daniel
authors.initials: D
authors.lastname: Vaughan
authors.forename: Vadim
authors.initials: V
authors.lastname: Zalunin
mesh_terms: D001483:Base Sequence; D044962:Data Compression; D030561:Databases, Nucleic Acid; D023281:Genomics; D059014:High-Throughput Nucleotide Sequencing; D020407:Internet; D014584:User-Computer Interface