title: Hydrolytic stability of three-step etch-and-rinse adhesives in occlusal class-I cavities.
abstract: OBJECTIVE
  A dental adhesive without small and hydrophilic monomers such as 2-hydroxyethyl methacrylate (HEMA) and triethylene glycol dimethacrylate (TEGDMA) would be beneficial in order to avoid contact allergies. However, these monomers are important to increase infiltration and polymerization of the adhesive. Therefore, the purpose of this study was to evaluate the bonding effectiveness and bond durability of a more hydrophobic and biocompatible adhesive as compared to a conventional three-step etch-and-rinse adhesive.
  
  
  METHODS
  Sixteen non-carious human third molars were used to determine the micro-tensile bond strength testing (μTBS) and interfacial ultrastructure by transmission electron microscopy (TEM) of the more hydrophobic cmf adhesive system (Saremco) adhesive as compared to the control OptiBond FL (Kerr).
  
  
  RESULTS
  The more hydrophobic and biocompatible three-step etch-and-rinse adhesive was able to produce a reasonable short-time bonding effectiveness. In the long term, the collagen fibrils in the hybrid layer were not effectively protected and were prone to hydrolytic degradation. As a result, long-term bonding effectiveness of this novel adhesive was very low.
  
  
  CONCLUSIONS
  Application of a more hydrophobic adhesive without altering the application procedure considerably results in a reduced durability of the created bond
  
  
  CONCLUSIONS
  Omitting small and hydrophilic components from the adhesive formulation may impair the durability of your composite restoration.
authors.affiliation: KU Leuven Biomat, Department of Oral Health Sciences, KU Leuven (University of Leuven), Louvain, Belgium, jan.demunck@med.kuleuven.be.
authors.forename: Jan
authors.initials: J
authors.lastname: De Munck
authors.forename: Atsushi
authors.initials: A
authors.lastname: Mine
authors.forename: Marcio
authors.initials: M
authors.lastname: Vivan Cardoso
authors.forename: Kirsten L
authors.initials: KL
authors.lastname: Van Landuyt
authors.forename: Anne-Katrin
authors.initials: AK
authors.lastname: Lührs
authors.forename: André
authors.initials: A
authors.lastname: Poitevin
authors.forename: Masao
authors.initials: M
authors.lastname: Hanabusa
authors.forename: Takuo
authors.initials: T
authors.lastname: Kuboki
authors.forename: Bart
authors.initials: B
authors.lastname: Van Meerbeek
mesh_terms: D000134:Acid Etching, Dental / Q000379:methods*; D001840:Dental Bonding; D003731:Dental Caries / Q000628:therapy*; D003738:Dental Cements; D006801:Humans; D006868:Hydrolysis; D008311:Malocclusion, Angle Class I / Q000628:therapy*; D046529:Microscopy, Electron, Transmission; D013718:Tensile Strength
chemical_list: D003738:Dental Cements