title: Benzimidazole derivatives as potential anticancer agents.
abstract: Benzimidazole ring system is found in many bioactive heterocyclic compounds because of their diverse biological and clinical applications. Furthermore, benzimidazole derivatives are structural isosters of naturally occurring nucleotides, thus they can interact with biological macromolecules such as proteins, enzymes and receptors. This review discusses the benzimidazole derivatives which possess anticancer activity of medicinal efficacy.
authors.affiliation: Natural and Microbial Department, National Research Centre, Dokki, Cairo 12311, Egypt.
authors.forename: Ahmed A
authors.initials: AA
authors.lastname: El Rashedy
authors.forename: Hassan Y
authors.initials: HY
authors.lastname: Aboul-Enein
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D001562:Benzimidazoles / Q000494:pharmacology*; D045744:Cell Line, Tumor; D006801:Humans
chemical_list: D000970:Antineoplastic Agents; D001562:Benzimidazoles