title: The impact of deep brain stimulation on the nonmotor symptoms of Parkinson's disease.
abstract: Deep brain stimulation (DBS) is a well-established therapy for patients with advanced Parkinson's disease (PD) with clear benefits on many of the motor symptoms. The effects of DBS on the nonmotor symptoms are less well examined. Emergence of tools to measure the nonmotor burden in PD is now allowing a more objective assessment of impact of DBS on such symptoms. Here we review the pertinent evidence and conclude that, as a therapy, DBS has a major potential to contribute towards the holistic care of PD patients.
authors.affiliation: Department of Neurosurgery, King's College Hospital, Denmark Hill, London, SE5 9RS, UK. k.ashkan@nhs.net
authors.forename: Keyoumars
authors.initials: K
authors.lastname: Ashkan
authors.forename: Michael
authors.initials: M
authors.lastname: Samuel
authors.forename: Prashanth
authors.initials: P
authors.lastname: Reddy
authors.forename: K
authors.initials: K
authors.lastname: Ray Chaudhuri
mesh_terms: D046690:Deep Brain Stimulation; D006801:Humans; D010146:Pain / Q000150:complications; D059408:Pain Management; D010300:Parkinson Disease / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome; D053201:Urinary Bladder, Overactive / Q000150:complications / Q000628:therapy*