title: Primary pancreatic Ewing's sarcoma with portal vein tumor thrombosis.
abstract: BACKGROUND
  Extraosseous Ewing's sarcoma (EES) is a mesenchyme-derived small blue cell tumor, which is distinguished by its rarity, aggressiveness, dismal prognosis, and distinct pathogenesis. Occurring almost exclusively among children and young adults, EES can arise from a variety of organs and portends a rapid clinical deterioration and high likelihood of recurrence.
  
  
  CONCLUSIONS
  We present the first reported case of a primary pancreatic Ewing's sarcoma in a patient with concomitant portal vein thrombosis. The atypical presentation of this extraordinarily rare tumor underscores the imperative to maintain EES in the differential diagnosis of suspicious, indistinct pancreatic lesions in young patients. In addition, we review the available literature describing additional cases of primary pancreatic Ewing's sarcoma.
authors.affiliation: University of Central Florida College of Medicine, Oviedo, FL 32765, USA. creilly@knights.ucf.edu
authors.forename: Chris
authors.initials: C
authors.lastname: Reilly
authors.forename: Scott
authors.initials: S
authors.lastname: Zenoni
authors.forename: Muhammad K
authors.initials: MK
authors.lastname: Hasan
authors.forename: Shyam
authors.initials: S
authors.lastname: Varadarajulu
authors.forename: Tien-Anh
authors.initials: TA
authors.lastname: Tran
authors.forename: Sebastian G
authors.initials: SG
authors.lastname: de la Fuente
authors.forename: Juan P
authors.initials: JP
authors.lastname: Arnoletti
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D011169:Portal Vein; D012512:Sarcoma, Ewing / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D014057:Tomography, X-Ray Computed; D020246:Venous Thrombosis / Q000150:complications* / Q000175:diagnosis; D055815:Young Adult