title: Febrile complications after endobronchial ultrasound-guided transbronchial needle aspiration for intra-pulmonary mass lesions of lung cancer--a series of 3 cases.
abstract: Recent case reports have shown that endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for mediastinal lesions is sometimes accompanied by severe infectious complications. Here, we report 3 cases with refractory febrile complications following EBUS-TBNA for intra-pulmonary large mass lesion of lung cancer (squamous cell carcinoma, n=2; adenocarcinoma, n=1). After the EBUS-TBNA, all cases showed prolonged fever and systemic inflammation despite receiving a sufficient dose of broad-spectrum antibiotics. The presence of a low-density area inside the masses upon CT examination, suggesting necrosis, may be a predictive sign of febrile complications associated with EBUS-TBNA.
authors.affiliation: Department of Respiratory Medicine, Nagoya Graduate School of Medicine, Nagoya, Japan.
authors.forename: Tomoyo
authors.initials: T
authors.lastname: Oguri
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Imai
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Imaizumi
authors.forename: Momen
authors.initials: M
authors.lastname: Elshazley
authors.forename: Izumi
authors.initials: I
authors.lastname: Hashimoto
authors.forename: Naozumi
authors.initials: N
authors.lastname: Hashimoto
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Hasegawa
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D000368:Aged; D001707:Biopsy, Needle / Q000009:adverse effects*; D001980:Bronchi; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D019160:Endosonography / Q000009:adverse effects*; D005260:Female; D005334:Fever / Q000209:etiology*; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male