title: An unusual silicon mediated transannular cyclopropanation.
abstract: A silicon mediated intramolecular 1,4-conjugate addition of a homoallylic carbon nucleophile leading to cyclopropanation is reported. Specifically, treatment of 6-trimethylsilyl-5,6-dihydroazocinones with fluoride gives 4-azabicyclo(5.1.0)octenones, presenting an unusual extension to the repertoire of silyl group reactivity.
authors.affiliation: School of Chemistry, University of Nottingham, University Park, UK.
authors.forename: Bing
authors.initials: B
authors.lastname: You
authors.forename: Kate
authors.initials: K
authors.lastname: Hamer
authors.forename: William
authors.initials: W
authors.lastname: Lewis
authors.forename: James
authors.initials: J
authors.lastname: Dowden
mesh_terms: D000498:Allyl Compounds / Q000737:chemistry; D001392:Azocines / Q000737:chemistry; D003500:Cyclization; D005459:Fluorides / Q000737:chemistry; D011407:Propane / Q000737:chemistry*; D012825:Silicon / Q000737:chemistry*
chemical_list: D000498:Allyl Compounds; D001392:Azocines; D005459:Fluorides; D011407:Propane; D012825:Silicon