title: Ocular symptoms are not predictive of ophthalmologic inflammation in inflammatory bowel disease.
abstract: BACKGROUND
  Ocular manifestations are frequent in patients with inflammatory bowel disease.
  
  
  OBJECTIVE
  To evaluate for the first time the value of ocular symptoms in predicting ophthalmologic inflammation in inflammatory bowel disease.
  
  
  METHODS
  All consecutive inflammatory bowel disease patients seen in the Department of Gastroenterology (Nancy, University Hospital, France) between April 2009 and July 2011 were interviewed for this cross-sectional study using a pre-established questionnaire. If the patient had at least one ocular symptom, he systematically underwent an ophthalmologic examination (visual acuity, Break-Up Time test, Schirmer Test, slit-lamp exam with fundus examination).
  
  
  RESULTS
  This cross-sectional survey was completed by 305 patients: 169 were women (55.2%), 228 had Crohn's disease (74.5%). Ninety-eight patients (32%) reported at least one ocular symptom: ocular irritation (56.8%), red eye (40.5%), blurred vision (37.8%), progressive visual loss (34.4%), ocular pain (31.1%), myodesopsia (23.3%), eyelid secretion (12.2%), dry eye (9.5%), watering (6.8%), diplopia (5.4%), metamorphopsia (4%), and sudden visual loss (4%). Following ophthalmologic examination (n=74), 41.9% patients had evidence of dry eye (n=31), 14.9% blepharitis (n=11) and 1.4% scleritis (n=1). No uveitis was reported.
  
  
  CONCLUSIONS
  Ocular symptoms are frequent in inflammatory bowel disease, but are non-specific and rarely associated with ocular inflammation. Systematic ocular symptoms assessment is of poor value for diagnosing ocular inflammation in inflammatory bowel disease.
authors.affiliation: Department of Ophthalmology, Nancy University Hospital, Vandoeuvre-lès-Nancy, France.
authors.forename: Véronique
authors.initials: V
authors.lastname: Cloché
authors.forename: Anthony
authors.initials: A
authors.lastname: Buisson
authors.forename: Fanny
authors.initials: F
authors.lastname: Tréchot
authors.forename: Benjamine
authors.initials: B
authors.lastname: Batta
authors.forename: Andy
authors.initials: A
authors.lastname: Locatelli
authors.forename: Constance
authors.initials: C
authors.lastname: Favel
authors.forename: Shanour
authors.initials: S
authors.lastname: Premy
authors.forename: Benjamin
authors.initials: B
authors.lastname: Collet-Fenetrier
authors.forename: Estelle
authors.initials: E
authors.lastname: Fréling
authors.forename: Anthony
authors.initials: A
authors.lastname: Lopez
authors.forename: Marie Pauline
authors.initials: MP
authors.lastname: Massoure
authors.forename: Anne-Laure
authors.initials: AL
authors.lastname: Humbert
authors.forename: Franck
authors.initials: F
authors.lastname: Hansmannel
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Guéant
authors.forename: Marc-André
authors.initials: MA
authors.lastname: Bigard
authors.forename: Laurent
authors.initials: L
authors.lastname: Peyrin-Biroulet
authors.forename: Karine
authors.initials: K
authors.lastname: Angioi
mesh_terms: D000328:Adult; D001762:Blepharitis / Q000150:complications / Q000175:diagnosis; D015331:Cohort Studies; D003093:Colitis, Ulcerative / Q000150:complications*; D003424:Crohn Disease / Q000150:complications*; D003430:Cross-Sectional Studies; D015352:Dry Eye Syndromes / Q000150:complications / Q000175:diagnosis; D005128:Eye Diseases / Q000150:complications* / Q000175:diagnosis; D058447:Eye Pain / Q000150:complications / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015423:Scleritis / Q000150:complications / Q000175:diagnosis; D057566:Self Report; D011795:Surveys and Questionnaires; D014605:Uveitis / Q000150:complications / Q000175:diagnosis; D014786:Vision Disorders / Q000150:complications / Q000175:diagnosis