title: Morphometric findings in avascular necrosis of the femoral head.
abstract: Avascular necrosis of the femoral head is an illness with a controversial etiology, the trigger event being the suppression of blood flow to the femoral head. The disease affects mostly young adults within their third and fifth decade, the majority of the patients being men. The main risk factors are trauma, chronic alcohol consumption, smoking, corticotherapy. The main goal of our study is to describe the morphometric changes found in the bone tissue of patients diagnosed with avascular necrosis of the femoral head, with different risk factors, by comparing the area of bone trabeculae inside the area of necrosis with that from the adjacent viable tissue. The morphometric study used biological material from 16 patients with ages between 29 and 57 years, who underwent surgery for avascular necrosis of the femoral head. They were admitted in the Orthopedics Department at the Emergency County Hospital in Craiova between 2010 and 2011 and were split into four groups. Group I presented trauma as the main risk factor, Group II had corticotherapy as the defining risk factor, Group III presented chronic alcohol consumption and Group IV was represented by the patients who smoked and exhibited chronic alcohol consumption. There was not a significant statistical difference between the areas of bone trabeculae of the four groups when we compared viable bone tissue to the necrotized one. Knowing the risk factors of the avascular necrosis of the femoral head is critical to the management of the disease, because diagnosing it in an early stage is a necessity for obtaining a good result for conservative treatment.
authors.affiliation: Department of Physical Medicine and Rehabilitation, University of Medicine and Pharmacy of Craiova, 2-4 Petru Rareş Street, Craiova, Romania.
authors.forename: Diana
authors.initials: D
authors.lastname: Kamal
authors.forename: Rodica
authors.initials: R
authors.lastname: Trăistaru
authors.forename: D O
authors.initials: DO
authors.lastname: Alexandru
authors.forename: C K
authors.initials: CK
authors.lastname: Kamal
authors.forename: D
authors.initials: D
authors.lastname: Pirici
authors.forename: O T
authors.initials: OT
authors.lastname: Pop
authors.forename: D Gh
authors.initials: DG
authors.lastname: Mălăescu
mesh_terms: D000328:Adult; D005260:Female; D005270:Femur Head / Q000473:pathology*; D005271:Femur Head Necrosis / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors