title: Recurrent mesalazine-induced myopericarditis in a patient with ulcerative colitis.
abstract: Inflammatory bowel disease (IBD) is considered as a dysregulated immune mediated disease. Pericarditis in IBD is a very rare disease both as an extra-intestinal manifestation of IBD and an adverse reaction of therapeutic drug for IBD such as mesalazine or sulfasalazine. A 26-year-old IBD male patient who had been taking mesalazine regularly for about 1 month was referred to our hospital because of fever, chest discomfort, and abnormal electrocardiographic findings. The patients was diagnosed as acute myopericarditis, and recovered after cessation of mesalazine using steroid and aspirin. When mesalazine was re-medicated some days after discharge, he suffered from myopericarditis again. Subsequently, myopericarditis was resolved just after cessation of mesalazine again. These findings suggest that the development of myopericarditis is caused by mesalazine.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors.forename: Eun Hye
authors.initials: EH
authors.lastname: Park
authors.forename: Byung Jin
authors.initials: BJ
authors.lastname: Kim
authors.forename: Jung Kwon
authors.initials: JK
authors.lastname: Huh
authors.forename: Eun Haeng
authors.initials: EH
authors.lastname: Jeong
authors.forename: Sang Hyuk
authors.initials: SH
authors.lastname: Lee
authors.forename: Ki Bae
authors.initials: KB
authors.lastname: Bang
authors.forename: Ji Soo
authors.initials: JS
authors.lastname: Seol
authors.forename: Joo Wook
authors.initials: JW
authors.lastname: Sung
authors.forename: Bum Soo
authors.initials: BS
authors.lastname: Kim
authors.forename: Jin Ho
authors.initials: JH
authors.lastname: Kang