title: Novel biopolymers to enhance endothelialisation of intra-vascular devices.
abstract: Rapid endothelisation is of critical importance in the prevention of adverse remodelling after device implantation. Currently, there is a need for alternative strategies to promote re-endothelialisation for intravascular stents and vascular grafts. Using polymer microarray technology 345 polymers are comprehensively assessed and a matrix is identified that specifically supports both progenitor and mature endothelial cell activity in vitro and in vivo while minimising platelet attachment.
authors.affiliation: School of Chemistry, University of Edinburgh, West Mains Road, Edinburgh EH9 3JJ, UK.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Pernagallo
authors.forename: Olga
authors.initials: O
authors.lastname: Tura
authors.forename: Mei
authors.initials: M
authors.lastname: Wu
authors.forename: Kay
authors.initials: K
authors.lastname: Samuel
authors.forename: Juan J
authors.initials: JJ
authors.lastname: Diaz-Mochon
authors.forename: Anna
authors.initials: A
authors.lastname: Hansen
authors.forename: Rong
authors.initials: R
authors.lastname: Zhang
authors.forename: Melany
authors.initials: M
authors.lastname: Jackson
authors.forename: Gareth J
authors.initials: GJ
authors.lastname: Padfield
authors.forename: Patrick W F
authors.initials: PW
authors.lastname: Hadoke
authors.forename: Nicholas L
authors.initials: NL
authors.lastname: Mills
authors.forename: Marc L
authors.initials: ML
authors.lastname: Turner
authors.forename: John P
authors.initials: JP
authors.lastname: Iredale
authors.forename: David C
authors.initials: DC
authors.lastname: Hay
authors.forename: Mark
authors.initials: M
authors.lastname: Bradley
mesh_terms: D001807:Blood Vessel Prosthesis; D002448:Cell Adhesion / Q000502:physiology; D049109:Cell Proliferation; D002470:Cell Survival / Q000502:physiology; D002478:Cells, Cultured; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D042783:Endothelial Cells / Q000166:cytology / Q000502:physiology*; D006801:Humans; D008422:Materials Testing; D015607:Stents
chemical_list: D020099:Coated Materials, Biocompatible