title: Global control of cell growth in fission yeast and its coordination with the cell cycle.
abstract: Cell growth is a fundamental process for every cell but its pleiotropic complexity makes it difficult to comprehend. Global aspects of cellular growth, like the overall determinants of growth rate are not well understood. Here we examine the cell growth pattern of the fission yeast Schizosaccharomyces pombe during the mitotic and meiotic cell cycles. We also explore recent findings illuminating aspects of cell size homeostasis and cell growth regulation, and propose that there are global controls over growth acting at the level of the cell.
authors.affiliation: Cell Cycle Lab, Cancer Research UK, London Research Institute. 44 Lincoln's Inn Fields, London, WC2A 3LY, UK. Francisco.Navarro@cancer.org.uk
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Navarro
authors.forename: Louise
authors.initials: L
authors.lastname: Weston
authors.forename: Paul
authors.initials: P
authors.lastname: Nurse
mesh_terms: D002453:Cell Cycle / Q000235:genetics / Q000502:physiology; D049109:Cell Proliferation; D012568:Schizosaccharomyces / Q000166:cytology* / Q000235:genetics / Q000378:metabolism*; D029702:Schizosaccharomyces pombe Proteins / Q000235:genetics / Q000378:metabolism
chemical_list: D029702:Schizosaccharomyces pombe Proteins