title: IgG myeloma presenting as a large mediastinal mass and pleural effusion.
abstract: Plasmacytoma, a rare form of plasma cell dyscrasia, refers to a neoplastic proliferation of plasma cells. Although the upper aerodigestive tract is the most common site for extramedullary plasmacytoma, mediastinal and pleural involvement is extremely rare. We report the case of a patient who presented with a large mediastinal mass and pleural effusion. Diagnosis was challenging and subsequently made as mediastinal extramedullary plasmacytoma with simultaneous myelomatous pleural effusion. Further investigations revealed multiple myeloma.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, VA Medical Center, Minneapolis, MN, USA.
authors.forename: Erin
authors.initials: E
authors.lastname: Raci-Wetherbee
authors.forename: H Erhan
authors.initials: HE
authors.lastname: Dincer
mesh_terms: D000368:Aged; D044963:Biopsy, Fine-Needle; D001797:Blood Protein Electrophoresis; D001999:Bronchoscopy; D002637:Chest Pain / Q000175:diagnosis / Q000209:etiology; D003937:Diagnosis, Differential; D004322:Drainage; D019160:Endosonography; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008481:Mediastinoscopy; D009101:Multiple Myeloma / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D010954:Plasmacytoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D016066:Pleural Effusion, Malignant / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D007074:Immunoglobulin G