title: Multiple cavernomas of the brain: simultaneous hemorrhage of two lesions in a non-familial form.
abstract: BACKGROUND
  Cavernomas of the brain are congenital lesions clinically divided     into hereditary and a sporadic forms. Multiple lesions are usually observed in     the familial form, whereas the sporadic variant generally shows a single     cavernoma. In this case we describe the simultaneous bleeding of two lesions in     a patient with a non-familial cavernomatosis.
  
  
  METHODS
  A 46-year-old     woman presented with slight hyposthenia involving the left arm and cervical     stiffness. Examinations revealed two cavernomas with recent signs of bleeding.     The lesions were surgically removed achieving a total excision. The patient was     discharged after 10 days with slight left hyposthenia.
  
  
  CONCLUSIONS
  Simultaneous     hemorrhage of multiple cavernomas is rare. To the best of our knowledge, this is     the first case showing a sporadic form presenting with two hemorrhagic lesions.     We suggest an aggressive approach in order to avoid the risk of rebleeding,     which is particularly high in case of hemorrhagic cavernomatosis.
authors.affiliation: University of Turin, Department of Neuroscience, Division of Neurosurgery, Via Cherasco, Torino, Italy. vincy.bip@alice.it
authors.forename: Pier Paolo
authors.initials: PP
authors.lastname: Panciani
authors.forename: Alessandro
authors.initials: A
authors.lastname: Agnoletti
authors.forename: Riccardo
authors.initials: R
authors.lastname: Fornaro
authors.forename: Marco
authors.initials: M
authors.lastname: Fontanella
authors.forename: Alessandro
authors.initials: A
authors.lastname: Ducati
mesh_terms: D001921:Brain / Q000473:pathology / Q000601:surgery*; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005260:Female; D020786:Hemangioma, Cavernous, Central Nervous System / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D006470:Hemorrhage / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods; D012306:Risk; D016896:Treatment Outcome