title: Combined effect of sodium nitrite with high-pressure treatments on the inactivation of Escherichia coli BW25113 and Listeria monocytogenes NCTC 11994.
abstract: The bactericidal effect of acidified sodium nitrite alone or when combined with high hydrostatic pressure (HHP) treatment was examined with Escherichia coli BW25113 and Listeria monocytogenes NCTC 11994. A powerful synergistic effect of HHP plus nitrite was observed at pH 4·0, but not at higher pH values. Escherichia coli hmpA and norV mutants lacking defences against nitrosative stress were more sensitive to pressure combined with acidified sodium nitrite than the wild-type strain, suggesting an involvement of nitric oxide in the bactericidal effect.
authors.affiliation: Departamento de Tecnología de Alimentos, INIA, Carretera de La Coruña Km 7, Madrid, Spain.
authors.forename: M
authors.initials: M
authors.lastname: De Alba
authors.forename: D
authors.initials: D
authors.lastname: Bravo
authors.forename: M
authors.initials: M
authors.lastname: Medina
authors.forename: S F
authors.initials: SF
authors.lastname: Park
authors.forename: B M
authors.initials: BM
authors.lastname: Mackey
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015169:Colony Count, Microbial; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development*; D005516:Food Microbiology; D006863:Hydrogen-Ion Concentration; D006874:Hydrostatic Pressure; D008089:Listeria monocytogenes / Q000187:drug effects / Q000254:growth & development*; D009569:Nitric Oxide / Q000032:analysis; D012977:Sodium Nitrite / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D009569:Nitric Oxide; D012977:Sodium Nitrite