title: Tower microneedle via reverse drawing lithography for innocuous intravitreal drug delivery.
abstract: The "tower microneedle" (TM) via reverse drawing lithography for intravitreal injection by fabricating a long hollow microneedle on the blunt hypodermic needle: The hollow hole between the microneedle and hypodermic needle is aligned concentrically, and fifteen degree bevel angle is introduced to TM by laser cutting to achieve intravitreal injection with minimal damage to eye tissue.
authors.affiliation: Department of Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-749, Republic of Korea.
authors.forename: Chang Yeol
authors.initials: CY
authors.lastname: Lee
authors.forename: Kwang
authors.initials: K
authors.lastname: Lee
authors.forename: Yong Sung
authors.initials: YS
authors.lastname: You
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Lee
authors.forename: Hyungil
authors.initials: H
authors.lastname: Jung
mesh_terms: D000818:Animals; D004867:Equipment Design; D019544:Equipment Failure Analysis; D058449:Intravitreal Injections / Q000295:instrumentation*; D008845:Microinjections / Q000295:instrumentation*; D008904:Miniaturization; D054802:Molecular Imprinting / Q000295:instrumentation*; D009339:Needles; D010781:Photography / Q000295:instrumentation*; D011817:Rabbits