title: Neoadjuvant chemotherapy for invasive bladder cancer: an interesting case report.
abstract: We report the case of a 66 years old woman with histological diagnosis of muscle-invasive high grade transitional cell carcinoma and clinical diagnosis (TC) of metastatic disease treated with a platinum based combination chemotherapy obtaining a pathologic complete response. Neoadjuvant chemotherapy for bladder cancer even with its limitations regarding patients selection, current development of surgical technique and current chemotherapy combination has shown to improve overall survival by 5-7% at 5 years and should be considered in muscle invasive bladder cancer, irrespective of definitive treatment.
authors.affiliation: Department of Urology, European Institute of Oncology IEO - Università degli Studi di Milano, Milano, Italy. davide.adel@libero.it
authors.forename: Davide
authors.initials: D
authors.lastname: Abed El Rahman
authors.forename: Victor Deliu
authors.initials: VD
authors.lastname: Matei
authors.forename: Gennaro
authors.initials: G
authors.lastname: Musi
authors.forename: Danilo
authors.initials: D
authors.lastname: Bottero
authors.forename: Antonio
authors.initials: A
authors.lastname: Brescia
authors.forename: Giacomo
authors.initials: G
authors.lastname: Galasso
authors.forename: Federica
authors.initials: F
authors.lastname: Mazzoleni
authors.forename: Ottavio
authors.initials: O
authors.lastname: De Cobelli
mesh_terms: D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy* / Q000473:pathology; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D020360:Neoadjuvant Therapy; D009361:Neoplasm Invasiveness; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy* / Q000473:pathology