title: The use of leukocyte- and platelet-rich fibrin (L-PRF) to facilitate implant placement in bone-deficient sites: a report of two cases.
abstract: Successful dental implant treatment usually requires that the implant be placed in the ideal anatomic position, so that it will readily facilitate the placement of a functional and aesthetically acceptable restoration. However, this is not always possible, and in many cases augmentation procedures may be required to compensate for lost tissue structures. These interventions often require more complex surgery, as well as the use of graft material derived from animal sources. Leukocyte- and patelet-rich fibrin (LPRF) is a newly developed platelet concentrate that has successfully been used in a number of surgical procedures to optimise wound healing. Several studies indicate that it may also have the ability to stimulate bone formation. In this article we present two cases where L-PRF was used to stimulate bone formation to facilitate ideal placement of implants.
authors.affiliation: Department of Oral Medicine and Periodontology, Faculty of Dentistry, University of the Western Cape, Cape Town, South Africa. 9552379@uwc.ac.za
authors.forename: M T
authors.initials: MT
authors.lastname: Peck
authors.forename: J
authors.initials: J
authors.lastname: Marnewick
authors.forename: L X G
authors.initials: LX
authors.lastname: Stephen
authors.forename: A
authors.initials: A
authors.lastname: Singh
authors.forename: N
authors.initials: N
authors.lastname: Patel
authors.forename: A
authors.initials: A
authors.lastname: Majeed
mesh_terms: D001792:Blood Platelets / Q000502:physiology; D001861:Bone Regeneration / Q000187:drug effects*; D003758:Dental Implantation, Endosseous / Q000379:methods*; D019232:Dental Restoration Failure; D020878:Device Removal; D005260:Female; D005337:Fibrin / Q000494:pharmacology*; D006801:Humans; D007962:Leukocytes / Q000502:physiology; D008297:Male; D008875:Middle Aged; D053657:Platelet-Rich Plasma; D012086:Reoperation; D059546:Sinus Floor Augmentation; D020390:Tooth Socket / Q000601:surgery*
chemical_list: D005337:Fibrin