title: Treatment of hemimandibular paresthesia in a patient with bisphosphonate-related osteonecrosis of the jaw (BRONJ) by combining surgical resection and PRGF-Endoret.
abstract: We report a case of a 50-year-old patient with bisphosphonate-related osteonecrosis of the jaws (BRONJs) whose symptoms included severe pain and hemimandibular paraesthesia. The treatment included resection of necrotic bone and the application of plasma rich in growth factors (PRGF(®)-Endoret(®)). We closed the ulcer in the soft tissue and her pain and paraesthesia improved. One year postoperatively sensitivity was totally recovered, pain was absent and bone was partially regenerated.
authors.affiliation: Private Practice in Implantology and Oral Rehabilitation in Vitoria, Spain. Electronic address: eduardoanitua@eduardoanitua.com.
authors.forename: E
authors.initials: E
authors.lastname: Anitua
authors.forename: L
authors.initials: L
authors.lastname: Begoña
authors.forename: G
authors.initials: G
authors.lastname: Orive
mesh_terms: D059266:Bisphosphonate-Associated Osteonecrosis of the Jaw / Q000188:drug therapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008336:Mandibular Diseases / Q000188:drug therapy / Q000601:surgery*; D008340:Mandibular Nerve / Q000187:drug effects / Q000503:physiopathology; D008875:Middle Aged; D019226:Oral Ulcer / Q000188:drug therapy / Q000601:surgery; D010292:Paresthesia / Q000188:drug therapy / Q000601:surgery*; D053657:Platelet-Rich Plasma / Q000502:physiology*; D062326:Re-Epithelialization / Q000187:drug effects; D020127:Recovery of Function / Q000187:drug effects; D059708:Ultrasonic Surgical Procedures / Q000379:methods