title: ViralZone: recent updates to the virus knowledge resource.
abstract: ViralZone (http://viralzone.expasy.org) is a knowledge repository that allows users to learn about viruses including their virion structure, replication cycle and host-virus interactions. The information is divided into viral fact sheets that describe virion shape, molecular biology and epidemiology for each viral genus, with links to the corresponding annotated proteomes of UniProtKB. Each viral genus page contains detailed illustrations, text and PubMed references. This new update provides a linked view of viral molecular biology through 133 new viral ontology pages that describe common steps of viral replication cycles shared by several viral genera. This viral cell-cycle ontology is also represented in UniProtKB in the form of annotated keywords. In this way, users can navigate from the description of a replication-cycle event, to the viral genus concerned, and the associated UniProtKB protein records.
authors.affiliation: SIB Swiss Institute of Bioinformatics, Swiss-Prot Group, Centre Médical Universitaire, CH-1211 Geneva 4, Switzerland.
authors.forename: Patrick
authors.initials: P
authors.lastname: Masson
authors.forename: Chantal
authors.initials: C
authors.lastname: Hulo
authors.forename: Edouard
authors.initials: E
authors.lastname: De Castro
authors.forename: Hans
authors.initials: H
authors.lastname: Bitter
authors.forename: Lore
authors.initials: L
authors.lastname: Gruenbaum
authors.forename: Laurent
authors.initials: L
authors.lastname: Essioux
authors.forename: Lydie
authors.initials: L
authors.lastname: Bougueleret
authors.forename: Ioannis
authors.initials: I
authors.lastname: Xenarios
authors.forename: Philippe
authors.initials: P
authors.lastname: Le Mercier
mesh_terms: D030541:Databases, Genetic; D016679:Genome, Viral; D006515:Hepatitis B virus / Q000502:physiology; D054884:Host-Pathogen Interactions; D020407:Internet; D014764:Viral Proteins / Q000235:genetics; D053586:Virus Internalization; D018406:Virus Physiological Phenomena; D014779:Virus Replication; D018875:Vocabulary, Controlled
chemical_list: D014764:Viral Proteins