title: Palladium-catalyzed insertion of α-diazocarbonyl compounds for the synthesis of cyclic amino esters.
abstract: Two different cyclic amino esters are synthesized by palladium-catalyzed cross-coupling reaction of diazoesters with N-substituted-2-iodoanilines. Aryldiazoacetates lead to cyclic α-amino esters with an α-quaternary carbon centre in the presence of CO. Additionally, arylvinyldiazoacetates afford cyclic α,β-unsaturated γ-amino esters.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
authors.forename: Ping-Xin
authors.initials: PX
authors.lastname: Zhou
authors.forename: Zhao-Zhao
authors.initials: ZZ
authors.lastname: Zhou
authors.forename: Zi-Sheng
authors.initials: ZS
authors.lastname: Chen
authors.forename: Yu-Ying
authors.initials: YY
authors.lastname: Ye
authors.forename: Lian-Biao
authors.initials: LB
authors.lastname: Zhao
authors.forename: Yan-Fang
authors.initials: YF
authors.lastname: Yang
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Xia
authors.forename: Jian-Yi
authors.initials: JY
authors.lastname: Luo
authors.forename: Yong-Min
authors.initials: YM
authors.lastname: Liang
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry; D001391:Azo Compounds / Q000737:chemistry; D002384:Catalysis; D003500:Cyclization; D004952:Esters; D007454:Iodides / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000814:Aniline Compounds; D001391:Azo Compounds; D004952:Esters; D007454:Iodides; D007659:Ketones; D010165:Palladium; C023650:aniline