title: [Artificial silicious-carbon dioxide baths for the rehabilitation and secondary prophylaxis in the patients presenting with arterial hypertension associated with coronary heart disease].
abstract: The present paper is designed to report the results of a clinical study undertaken to estimate the efficacy of artificial silicious-carbon dioxide baths for the rehabilitation and secondary prophylaxis in the patients presenting with arterial hypertension associated with coronary heart disease. The study included 130 patients whose treatment outcome was compared with that in a group of patients treated with the use of ordinary silicious baths alone. It was shown that artificial silicious-carbon dioxide baths have an advantage over the ordinary silicious baths in that they produce a more pronounced therapeutic effect especially in the patients with the most severe forms of hypertension associated with cardiovascular disorders. This effect is due to the combined action of their constituent components, in the first place water soluble silicates and carbon dioxide. The simultaneous action of the water soluble silicon on the structure and permeability of cellular membranes coupled with the reduction of sensitivity of vascular beta-adrenorecepors to pressor agents and inhibition of aldosterone secretion from the adrenal glands under effect of carbon dioxide accounts for the more pronounced hypotensive, anti-ischemic, and antiarrhythmic effect of artificial silicious-carbon dioxide baths that is associated with the beneficial effect on the quality of life in the majority of the treated patients.
authors.forename: T I
authors.initials: TI
authors.lastname: Nikiforova
authors.forename: T A
authors.initials: TA
authors.lastname: Kniazeva
mesh_terms: D000368:Aged; D001494:Baths; D002245:Carbon Dioxide / Q000008:administration & dosage; D061545:Carbonated Water / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000534:rehabilitation*; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications / Q000534:rehabilitation*; D012825:Silicon / Q000008:administration & dosage
chemical_list: D061545:Carbonated Water; D002245:Carbon Dioxide; D012825:Silicon