title: Genome sequence of "Candidatus Methanomethylophilus alvus" Mx1201, a methanogenic archaeon from the human gut belonging to a seventh order of methanogens.
abstract: We report the draft genome sequence of "Candidatus Methanomethylophilus alvus" Mx1201, a methanogen present in the human gut. It was enriched from human feces under anaerobic conditions with methanol as the substrate. Its circular genome, of around 1.7 Mb, contains genes needed for methylotrophic methanogenesis from methanol and tri-, di-, and monomethylamine.
authors.affiliation: EA-4678 CIDAM, Conception Ingénierie et Développement de l'Aliment et du Médicament, Clermont Université, Université d'Auvergne, Clermont-Ferrand, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Borrel
authors.forename: Hugh M B
authors.initials: HM
authors.lastname: Harris
authors.forename: William
authors.initials: W
authors.lastname: Tottey
authors.forename: Agnès
authors.initials: A
authors.lastname: Mihajlovski
authors.forename: Nicolas
authors.initials: N
authors.lastname: Parisot
authors.forename: Eric
authors.initials: E
authors.lastname: Peyretaillade
authors.forename: Pierre
authors.initials: P
authors.lastname: Peyret
authors.forename: Simonetta
authors.initials: S
authors.lastname: Gribaldo
authors.forename: Paul W
authors.initials: PW
authors.lastname: O'Toole
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Brugère
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000693:Anaerobiosis; D001105:Archaea / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism; D019641:DNA, Archaeal / Q000235:genetics*; D005243:Feces / Q000382:microbiology; D041981:Gastrointestinal Tract / Q000382:microbiology*; D020745:Genome, Archaeal; D006801:Humans; D000432:Methanol / Q000378:metabolism; D008780:Methyltransferases / Q000235:genetics; D008969:Molecular Sequence Data; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012338:RNA, Ribosomal, 23S / Q000235:genetics; D017422:Sequence Analysis, DNA
chemical_list: D019641:DNA, Archaeal; D012336:RNA, Ribosomal, 16S; D012338:RNA, Ribosomal, 23S; D008780:Methyltransferases; D000432:Methanol