title: Three-dimensional surface reconstruction within noncontact diffuse optical tomography using structured light.
abstract: A main field in biomedical optics research is diffuse optical tomography, where intensity variations of the transmitted light traversing through tissue are detected. Mathematical models and reconstruction algorithms based on finite element methods and Monte Carlo simulations describe the light transport inside the tissue and determine differences in absorption and scattering coefficients. Precise knowledge of the sample's surface shape and orientation is required to provide boundary conditions for these techniques. We propose an integrated method based on structured light three-dimensional (3-D) scanning that provides detailed surface information of the object, which is usable for volume mesh creation and allows the normalization of the intensity dispersion between surface and camera. The experimental setup is complemented by polarization difference imaging to avoid overlaying byproducts caused by inter-reflections and multiple scattering in semitransparent tissue.
authors.affiliation: Philipps University Marburg, Department of Radiology, Baldingerstrasse, 35043 Marburg, Germany. baumk@med.unimarburg.de
authors.forename: Kirstin
authors.initials: K
authors.lastname: Baum
authors.forename: Raimo
authors.initials: R
authors.lastname: Hartmann
authors.forename: Tobias
authors.initials: T
authors.lastname: Bischoff
authors.forename: Jan O
authors.initials: JO
authors.lastname: Oelerich
authors.forename: Stephan
authors.initials: S
authors.lastname: Finkensieper
authors.forename: Johannes T
authors.initials: JT
authors.lastname: Heverhagen
mesh_terms: D000465:Algorithms; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008027:Light; D008029:Lighting / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity; D041622:Tomography, Optical / Q000379:methods*