title: Influence of albumin on the electrochemical behaviour of Zr in phosphate buffered saline solutions.
abstract: The corrosion behaviour of Zr in phosphate buffered saline (PBS) solutions with various concentrations (0-4 g L(-1)) of albumin was studied by electrochemical techniques and surface analysis. Addition of albumin to PBS solutions moved the open circuit potential (OCP) to less nobler direction. OCP, polarization resistance and impedance increased and the corrosion current decreased over immersion duration. At early stages of immersion, the resistance was increased with the concentration of albumin because of the high adsorption kinetics of albumin on metal. After the long term immersion, the resistance in PBS without albumin was higher than PBS with albumin owing to the anodic dissolution effect of albumin on metal. According to the analysis of effective capacitances, a normal distribution of time-constants was proposed to estimate the surface film on Zr. A corrosion mechanism of Zr in PBS with different albumin was proposed based on electrochemical analysis.
authors.affiliation: Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, T6G 2V4, Canada. luning@ualberta.ca
authors.forename: Lu-Ning
authors.initials: LN
authors.lastname: Wang
authors.forename: Xian-Qiu
authors.initials: XQ
authors.lastname: Huang
authors.forename: Alyssa
authors.initials: A
authors.lastname: Shinbine
authors.forename: Jing-Li
authors.initials: JL
authors.lastname: Luo
mesh_terms: D002021:Buffers; D003343:Corrosion; D058266:Dielectric Spectroscopy; D017097:Electric Impedance; D007700:Kinetics; D008422:Materials Testing / Q000379:methods; D009994:Osmolar Concentration; D010710:Phosphates / Q000737:chemistry*; D012710:Serum Albumin, Bovine / Q000737:chemistry*; D012965:Sodium Chloride / Q000737:chemistry*; D013499:Surface Properties / Q000187:drug effects; D015040:Zirconium / Q000737:chemistry*
chemical_list: D002021:Buffers; D010710:Phosphates; D012710:Serum Albumin, Bovine; D012965:Sodium Chloride; D015040:Zirconium