title: Long chain N-acyl homoserine lactone production by Enterobacter sp. isolated from human tongue surfaces.
abstract: We report the isolation of N-acyl homoserine lactone-producing Enterobacter sp. isolate T1-1 from the posterior dorsal surfaces of the tongue of a healthy individual.  Spent supernatants extract from Enterobacter sp. isolate T1-1 activated the biosensor Agrobacterium tumefaciens NTL4(pZLR4), suggesting production of long chain AHLs by these isolates. High resolution mass spectrometry analysis of these extracts confirmed that Enterobacter sp. isolate T1-1 produced a long chain N-acyl homoserine lactone, namely  N-dodecanoyl-homoserine lactone (C12-HSL). To the best of our knowledge, this is the first isolation of Enterobacter sp., strain T1-1 from the posterior dorsal surface of the human tongue and N-acyl homoserine lactones production by this bacterium.
authors.affiliation: Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia. yinwaifong@yahoo.com
authors.forename: Wai-Fong
authors.initials: WF
authors.lastname: Yin
authors.forename: Kathiravan
authors.initials: K
authors.lastname: Purmal
authors.forename: Shenyang
authors.initials: S
authors.lastname: Chin
authors.forename: Xin-Yue
authors.initials: XY
authors.lastname: Chan
authors.forename: Kok-Gan
authors.initials: KG
authors.lastname: Chan
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000096:biosynthesis; D004754:Enterobacter / Q000378:metabolism*; D006801:Humans; D013058:Mass Spectrometry; D014059:Tongue / Q000382:microbiology*
chemical_list: C088386:homoserine lactone; D015107:4-Butyrolactone