title: Synthesis, Structure and Antioxidant Activity of (Tetra-O-acetyl-β-D-galactopyranosyl)thiosemicarbazones of Substituted Benzaldehydes.
abstract: Some new substituted benzaldehyde (2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl) thiosemicarbazones were synthesised by reaction of 2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl thiosemicarbazide and different substituted benzaldehydes. The reaction was performed using conventional and microwave-assisted heating methods. The structures of thiosemicarbazones were confirmed by spectroscopic (IR, (1) H NMR, (13) C NMR and MS) method. The antioxidant activity of these thiosemicarbazones was evaluated, in vitro and in vivo, and it's shown that some of these compounds had significant antioxidant activity.
authors.affiliation: Department of Chemistry, College of Science, Hanoi National University, 19 Le Thanh Tong, Ha Noi 10000, Viet Nam.
authors.forename: Nguyen D
authors.initials: ND
authors.lastname: Thanh
authors.forename: Le T
authors.initials: le T
authors.lastname: Hoai