title: [Synthesis and anti-tumor properties of myelopeptide MP-1].
abstract: We have studied anti-tumor properties of bone marrow derived peptide Phe-Leu-Gly-Phe-Pro-Thr (MP-1) synthesized by classical methods. It was shown that MP-1 enhanced the effect ofcytostatic therapy of lymphatic leukemia P388 and increased latent growth period of P388 tumors implanted in irradiated mice. MP-1 also decreased metastasis of mouse breast adenocarcinoma Ca-755 after surgery.
authors.forename: L A
authors.initials: LA
authors.lastname: Fonina
authors.forename: E M
authors.initials: EM
authors.lastname: Treshchalina
authors.forename: R G
authors.initials: RG
authors.lastname: Belevskaia
authors.forename: A A
authors.initials: AA
authors.lastname: Az'muko
authors.forename: M A
authors.initials: MA
authors.lastname: Efremov
authors.forename: L A
authors.initials: LA
authors.lastname: Sedakova
authors.forename: E A
authors.initials: EA
authors.lastname: Kirilina
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000138:chemical synthesis; D045744:Cell Line, Tumor; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D007941:Leukemia P388 / Q000188:drug therapy / Q000532:radiotherapy; D051379:Mice; D009842:Oligopeptides / Q000008:administration & dosage / Q000138:chemical synthesis
chemical_list: D000970:Antineoplastic Agents; D009842:Oligopeptides; C048617:myelopeptides; D002945:Cisplatin