title: Direct-write assembly of 3D silk/hydroxyapatite scaffolds for bone co-cultures.
abstract: 3D silk/HA microperiodic scaffolds for bone tissue engineering and angiogenesis are fabricated by direct-write assembly. This approach can be used to control filament and spacing size in the scaffold to allow investigation of the effect of scaffold architecture on osteogenesis and vessel-like structure formation from stem cells and endothelial cells.
authors.affiliation: Department of Chemical and Biological Engineering and Biomedical Engineering, Tufts University, Medford, MA 02155, USA.
authors.forename: Lin
authors.initials: L
authors.lastname: Sun
authors.forename: Sara T
authors.initials: ST
authors.lastname: Parker
authors.forename: Daisuke
authors.initials: D
authors.lastname: Syoji
authors.forename: Xiuli
authors.initials: X
authors.lastname: Wang
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Lewis
authors.forename: David L
authors.initials: DL
authors.lastname: Kaplan
mesh_terms: D002454:Cell Differentiation; D002478:Cells, Cultured; D018920:Coculture Techniques / Q000295:instrumentation; D017886:Durapatite / Q000737:chemistry*; D042783:Endothelial Cells / Q000166:cytology* / Q000502:physiology; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology* / Q000502:physiology; D054802:Molecular Imprinting / Q000379:methods; D010006:Osteoblasts / Q000166:cytology* / Q000502:physiology; D010012:Osteogenesis / Q000502:physiology*; D047011:Silk / Q000737:chemistry* / Q000648:ultrastructure; D054457:Tissue Scaffolds
chemical_list: D047011:Silk; D017886:Durapatite