title: [Serological survys on anti-H1N1 IgG of blood donors in Dongguan].
abstract: OBJECTIVE
  To access the sustained immune effect in influenza A H1N1 vaccine vaccinated-blood donors as well as the level of anti-H1N1 IgG in unvaccinated-blood donors in order to provide reference for preventing and treating influenza A H1N1.
  
  
  METHODS
  Anti-H1N1 IgG was detected in 1166 vaccinated-blood donors as well as 1265 unvaccinated-blood donors by ELISA method in Dongguan from January 2010 to June 2010.
  
  
  RESULTS
  The mean positive rate and high-titer rate of anti-H1N1 IgG were 78.82% and 46.57% respectively, both of which were sustained at relatively high level after reaching their peak at vaccination time of 71-90 d. The mean positive rate of anti-H1N1 IgG in unvaccinated-blood donors was 26.01%. No difference was found in the positive rate of anti-H1N1 IgG among different gender or age groups (P > 0.05).
  
  
  CONCLUSIONS
  The influenza A H1N1 vaccine, with good sustained immune effect, plays an important role in preventing and treating influenza A H1N1. The positive rate of anti-H1N1 IgG in influenza A HIN1 vaccine unvaccinated-blood donors is low. Vaccination should be strengthened.
authors.affiliation: Central Blood Station of City, 523930 Guangdong, China. wdwn163@163.com
authors.forename: De-Wen
authors.initials: DW
authors.lastname: Wang
authors.forename: Fu-Ping
authors.initials: FP
authors.lastname: Liu
authors.forename: Bing
authors.initials: B
authors.lastname: Liang
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood* / Q000276:immunology; D001782:Blood Donors; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood* / Q000276:immunology; D053118:Influenza A Virus, H1N1 Subtype / Q000276:immunology* / Q000302:isolation & purification; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000276:immunology; D007251:Influenza, Human / Q000097:blood* / Q000276:immunology / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007252:Influenza Vaccines