title: Pharmaco-invasive approach for acute myocardial infarction.
abstract: Reperfusion therapies--percutaneous coronary intervention and fibrinolysis- can be viewed as complementary approaches for the treatment of an acute ST segment elevation myocardial infarction. The objective was to review current land mark trials that have settled the ground for discussion for the pharmacoinvasive approach. Shortening the time to reperfusion of the infarct artery by prompt initiation of pharmacological reperfusion followed by a mechanical approach may consolidate the initial reperfusion process and prevent reocclusion of the infarct artery. We suggest a TRANSFER-AMI-Pragmatic Indian model. This model of care involves the use of tenecteplase and percutaneous coronary intervention. It has the ability to aid in the categorical organization of patients dependent on factors such as the hemodynamic and financial status. Utilizing such a model may encourage a more standardized format when treating patients on an individual hospital basis. This may encourage cooperation between the prehospital personnel, hospitals (with or without percutaneous coronary intervention) and the government. The creation of regional systems of care for ST-segment elevation myocardial infarctions may guarantee that patients receive the adequate reperfusion therapy in a timely fashion.
authors.affiliation: Cardiology Research Foundation, Florida, USA.
authors.forename: Estefanía
authors.initials: E
authors.lastname: Oliveros
authors.forename: Zarna
authors.initials: Z
authors.lastname: Dahya
authors.forename: Camilo
authors.initials: C
authors.lastname: Peña
authors.forename: Sameer
authors.initials: S
authors.lastname: Mehta
mesh_terms: D004562:Electrocardiography; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D009203:Myocardial Infarction / Q000628:therapy*; D009204:Myocardial Revascularization / Q000379:methods*; D015912:Thrombolytic Therapy / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents