title: Supramolecular sensor for cancer-associated nitrosamines.
abstract: A supramolecular assay based on two fluorescent cucurbit[n]uril probes enables the recognition and quantification of nitrosamines, including cancer-associated nitrosamines, compounds that are difficult to recognize. The cross-reactive sensor leverages weak interactions and competition among the probe, metal, and guest, yielding high information density in the signal output (variance) and enabling the recognition of structurally similar guests.
authors.affiliation: Department of Chemistry and Center for Photochemical Sciences, Bowling Green State University, Bowling Green, Ohio 43403, United States.
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Minami
authors.forename: Nina A
authors.initials: NA
authors.lastname: Esipenko
authors.forename: Ben
authors.initials: B
authors.lastname: Zhang
authors.forename: Maria E
authors.initials: ME
authors.lastname: Kozelkova
authors.forename: Lyle
authors.initials: L
authors.lastname: Isaacs
authors.forename: Ryuhei
authors.initials: R
authors.lastname: Nishiyabu
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kubo
authors.forename: Pavel
authors.initials: P
authors.lastname: Anzenbacher
mesh_terms: D001952:Bridged-Ring Compounds / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D007093:Imidazoles / Q000737:chemistry*; D046911:Macromolecular Substances / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D009369:Neoplasms / Q000737:chemistry*; D009602:Nitrosamines / Q000737:chemistry*; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils
chemical_list: D001952:Bridged-Ring Compounds; D005456:Fluorescent Dyes; D007093:Imidazoles; D046911:Macromolecular Substances; D009602:Nitrosamines; C454805:cucurbit(6)uril; D047028:Macrocyclic Compounds; D000099246:Cucurbit(n)urils