title: Polyacrylamid/silver composite particles produced via microfluidic photopolymerization for single particle-based SERS microsensorics.
abstract: A micro-continuous-flow process was applied for the preparation of swellable polyacrylamide particles incorporating silver nanoparticles. These sensor particles are formed from a mixture of a colloidal solution of silver nanoparticles and monomer by a droplet-based procedure with in situ photoinitiation of polymerization and a subsequent silver enforcement in batch. The obtained polymer composite particles show a strong SERS effect. Characteristic Raman signals of aqueous solutions of adenine could be detected down to 0.1 μM by the use of single sensor particles. The chosen example demonstrates that the composite particles are suitable for quantitative microanalytical procedures with a high dynamic range (3 orders of magnitude for adenine).
authors.affiliation: Institute for Micro and Nanotechnologies/Institute of Chemistry and Biotechnology, Technical University Ilmenau, Germany. michael.koehler@tu-ilmenau.de
authors.forename: J Michael
authors.initials: JM
authors.lastname: Köhler
authors.forename: Anne
authors.initials: A
authors.lastname: März
authors.forename: Jürgen
authors.initials: J
authors.lastname: Popp
authors.forename: Andrea
authors.initials: A
authors.lastname: Knauer
authors.forename: Isabelle
authors.initials: I
authors.lastname: Kraus
authors.forename: Jaques
authors.initials: J
authors.lastname: Faerber
authors.forename: Christophe
authors.initials: C
authors.lastname: Serra