title: SIFTS: Structure Integration with Function, Taxonomy and Sequences resource.
abstract: The Structure Integration with Function, Taxonomy and Sequences resource (SIFTS; http://pdbe.org/sifts) is a close collaboration between the Protein Data Bank in Europe (PDBe) and UniProt. The two teams have developed a semi-automated process for maintaining up-to-date cross-reference information to UniProt entries, for all protein chains in the PDB entries present in the UniProt database. This process is carried out for every weekly PDB release and the information is stored in the SIFTS database. The SIFTS process includes cross-references to other biological resources such as Pfam, SCOP, CATH, GO, InterPro and the NCBI taxonomy database. The information is exported in XML format, one file for each PDB entry, and is made available by FTP. Many bioinformatics resources use SIFTS data to obtain cross-references between the PDB and other biological databases so as to provide their users with up-to-date information.
authors.affiliation: Protein Data Bank in Europe, EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK. sameer@ebi.ac.uk
authors.forename: Sameer
authors.initials: S
authors.lastname: Velankar
authors.forename: José M
authors.initials: JM
authors.lastname: Dana
authors.forename: Julius
authors.initials: J
authors.lastname: Jacobsen
authors.forename: Glen
authors.initials: G
authors.lastname: van Ginkel
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Gane
authors.forename: Jie
authors.initials: J
authors.lastname: Luo
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Oldfield
authors.forename: Claire
authors.initials: C
authors.lastname: O'Donovan
authors.forename: Maria-Jesus
authors.initials: MJ
authors.lastname: Martin
authors.forename: Gerard J
authors.initials: GJ
authors.lastname: Kleywegt
mesh_terms: D030562:Databases, Protein; D020407:Internet; D058977:Molecular Sequence Annotation; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry* / Q000145:classification / Q000502:physiology; D020539:Sequence Analysis, Protein; D018511:Systems Integration
chemical_list: D011506:Proteins