title: Alpha shape and Delaunay triangulation in studies of protein-related interactions.
abstract: In recent years, more 3D protein structures have become available, which has made the analysis of large molecular structures much easier. There is a strong demand for geometric models for the study of protein-related interactions. Alpha shape and Delaunay triangulation are powerful tools to represent protein structures and have advantages in characterizing the surface curvature and atom contacts. This review presents state-of-the-art applications of alpha shape and Delaunay triangulation in the studies on protein-DNA, protein-protein, protein-ligand interactions and protein structure analysis.
authors.affiliation: Department of Electronic Engineering, City University of Hong Kong, Tat Chee Avenue 83, Hong Kong. kenandzhou@hotmail.com.
authors.forename: Weiqiang
authors.initials: W
authors.lastname: Zhou
authors.forename: Hong
authors.initials: H
authors.lastname: Yan
mesh_terms: D000465:Algorithms; D001665:Binding Sites; D019295:Computational Biology; D004247:DNA / Q000235:genetics / Q000378:metabolism; D008024:Ligands; D008958:Models, Molecular; D011485:Protein Binding; D011487:Protein Conformation; D017510:Protein Folding; D054730:Protein Interaction Domains and Motifs; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism*; D040681:Structural Homology, Protein
chemical_list: D008024:Ligands; D011506:Proteins; D004247:DNA