title: [Management of anaphylaxis : part 2: treatment and emergency equipment].
abstract: Anaphylaxis is an extreme form of allergic reaction that can be life-threatening. Early treatment of circulatory and pulmonary disturbances is decisive for prognosis. Initial management of anaphylaxis comprises, where possible, interrupting allergen exposure; ensuring a stable airway; summoning emergency services; placing the patient in a safe position, obtaining venous access and monitoring vital signs. Adrenaline, histamine-antagonists and glucocorticoids have proven effective, as has administration of oxygen and volume substitutes. Many anaphylaxis patients are unable to successfully avoid the elicitor and the feasibility of self-treatment is limited if the patient is inadequately informed. An educational program for adult patients and parents of children with a high risk of anaphylaxis has been developed by the German Working Group for Anaphylaxis Training and Education (AGATE). This program aims to help prevent anaphylactic attacks, foster optimal first-line treatment and offer psychological and social support for anaphylaxis patients. Preliminary results confirm the efficacy of the AGATE approach. This article presents an overview of the stage-wise management of anaphylaxis in accordance with the S2 position paper of the German allergological societies and international guidelines.
authors.affiliation: Zentrum für Rhinologie & Allergologie, Wiesbaden, An den Quellen 10, 65183, Wiesbaden, Deutschland. Ludger.Klimek@allergiezentrum.org
authors.forename: L
authors.initials: L
authors.lastname: Klimek
authors.forename: U
authors.initials: U
authors.lastname: Goebel
authors.forename: A
authors.initials: A
authors.lastname: Glowania
mesh_terms: D000328:Adult; D000707:Anaphylaxis / Q000628:therapy*; D004632:Emergency Medical Services / Q000592:standards*; D004837:Epinephrine / Q000008:administration & dosage*; D004867:Equipment Design; D006801:Humans; D038622:Internationality; D010353:Patient Education as Topic / Q000592:standards; D056888:Patient Positioning / Q000295:instrumentation / Q000592:standards*; D017410:Practice Guidelines as Topic
chemical_list: D004837:Epinephrine