title: Effect of Liangxuehuayu Recipe on hemorheology in rats with blood stasis syndrome.
abstract: OBJECTIVE
  To investigate the effects of Liangxuehuayu Recipe on hemorheology in rats with blood stasis syndrome induced by mutifactor stimuli.
  
  
  METHODS
  SD rats were divided into control, model, Liangxuehuayu Recipe (high, middle and low dose, 18, 9, 4.5 g/kg accordingly). Except the control group, blood stasis model was established in the rest groups. The hemorheological parameters were measured and compared.
  
  
  RESULTS
  Blood viscosity at high, moderate and low level in rats with blood stasis significantly increased (P<0.05), but blood viscosity at high level and plasma viscosity was significantly decreased in rats induced by some stimuli after Liangxuehuayu Recipe were intra-gastrically administered for 1 weeks (P<0.01, P<0.05).
  
  
  CONCLUSIONS
  Liangxuehuayu Recipe is effective in improving hemorheology, and has important application value in the prevention of occurrence and development of ischemic stroke.
authors.affiliation: Nanjing University of Chinese Medicine, Nanjing, Jiangsu, 210038, China.
authors.forename: Song-Yi
authors.initials: SY
authors.lastname: Ning
authors.forename: Biao-Ping
authors.initials: BP
authors.lastname: Jiang
authors.forename: Li
authors.initials: L
authors.lastname: Xu
authors.forename: Tai-Hui
authors.initials: TH
authors.lastname: Fang
authors.forename: Mian-Hua
authors.initials: MH
authors.lastname: Wu
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001809:Blood Viscosity / Q000187:drug effects; D002449:Cell Aggregation / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004912:Erythrocytes / Q000187:drug effects / Q000473:pathology; D006402:Hematologic Diseases / Q000097:blood*; D018056:Hemorheology / Q000187:drug effects*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D004365:Drugs, Chinese Herbal