title: Investigation of the presence of human or bovine respiratory syncytial virus in the lungs of mink (Neovison vison) with hemorrhagic pneumonia due to Pseudomonas aeruginosa.
abstract: BACKGROUND
  Hemorrhagic pneumonia is a disease of farmed mink (Neovison vison) caused by Pseudomonas aeruginosa. The disease is highly seasonal in Danish mink with outbreaks occurring almost exclusively in the autumn. Human respiratory syncytial virus (RSV) has been shown to augment infection with P. aeruginosa in mice and to promote adhesion of P. aeruginosa to human respiratory cells.
  
  
  RESULTS
  We tested 50 lung specimens from mink with hemorrhagic pneumonia for bovine RSV by reverse transcriptase polymerase chain reaction (PCR) and for human RSV by a commercial real-time PCR. RSV was not found.
  
  
  CONCLUSIONS
  This study indicates that human and bovine RSV is not a major co-factor for development of hemorrhagic pneumonia in Danish mink.
authors.affiliation: National Veterinary Institute, Technical University of Denmark, Bülowsvej 27, DK-1870, Frederiksberg C, Denmark. charlottemarksoerensen@hotmail.com
authors.forename: Charlotte M
authors.initials: CM
authors.lastname: Salomonsen
authors.forename: Solvej Ø
authors.initials: SØ
authors.lastname: Breum
authors.forename: Lars E
authors.initials: LE
authors.lastname: Larsen
authors.forename: Jeanette
authors.initials: J
authors.lastname: Jakobsen
authors.forename: Niels
authors.initials: N
authors.lastname: Høiby
authors.forename: Anne S
authors.initials: AS
authors.lastname: Hammer
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D060085:Coinfection / Q000382:microbiology / Q000662:veterinary* / Q000821:virology; D003718:Denmark; D008168:Lung / Q000382:microbiology* / Q000821:virology; D008907:Mink; D011014:Pneumonia / Q000382:microbiology / Q000662:veterinary* / Q000821:virology; D011552:Pseudomonas Infections / Q000382:microbiology / Q000662:veterinary*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D012367:RNA, Viral / Q000235:genetics / Q000378:metabolism; D060888:Real-Time Polymerase Chain Reaction / Q000662:veterinary; D018357:Respiratory Syncytial Virus Infections / Q000662:veterinary* / Q000821:virology; D018112:Respiratory Syncytial Virus, Bovine / Q000302:isolation & purification; D018113:Respiratory Syncytial Virus, Human / Q000302:isolation & purification; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000662:veterinary
chemical_list: D012367:RNA, Viral