title: Intracystic papillary carcinoma of breast: report of three cases and review of the literature.
abstract: Intracystic papillary carcinoma (IPC) of the breast is a rare malignant tumour, found mainly but not exclusively in elderly women. IPC may be asymptomatic or presents with a palpable mass or blood-stained nipple discharge. The tumour is encysted within a dilated duct with arborisation of the fibrovascular stroma and contains nodules of papillary carcinoma surrounded by a thick fibrous capsule. Frequently excisional biopsy is required for diagnosis. The mainstay of treatment is breast-conserving surgery or mastectomy. Sentinel node biopsy could be considered in invasive cases. Adjuvant radiotherapy (XRT) and/or endocrine therapy is considered in appropriate cases. Prognosis is excellent. We report three such cases of IPC, in elderly women, which were successfully treated.
authors.affiliation: Department of Surgery, Tameside General Hospital, Ashton-under-lyne, UK. adhebri@hotmail.com
authors.forename: Alhad R
authors.initials: AR
authors.lastname: Dhebri
authors.forename: Amna
authors.initials: A
authors.lastname: Ahmad
authors.forename: Nigam
authors.initials: N
authors.lastname: Shah
authors.forename: Pardeep K
authors.initials: PK
authors.lastname: Arora
mesh_terms: D000368:Aged; D044963:Biopsy, Fine-Needle; D001940:Breast / Q000473:pathology; D047688:Breast Cyst / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D018275:Carcinoma, Lobular / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D002291:Carcinoma, Papillary / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology; D008327:Mammography; D008408:Mastectomy / Q000379:methods; D060787:Neoplasm Grading; D016609:Neoplasms, Second Primary / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D021701:Sentinel Lymph Node Biopsy / Q000379:methods; D016217:Ultrasonography, Mammary