title: Soluble-support-assisted electrochemical reactions: application to anodic disulfide bond formation.
abstract: A soluble-support-assisted technique was successfully applied to electrochemical reactions, leading to anodic disulfide bond formation. The support-bound peptide was soluble in electrolyte solution, allowing electron transfer at the surface of the electrodes. After completion of the reaction, the support-bound product was recovered as a precipitate by simple dilution of the reaction mixture with poor solvent.
authors.affiliation: Department of Applied Biological Science, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan.
authors.forename: Shingo
authors.initials: S
authors.lastname: Kitada
authors.forename: Masahito
authors.initials: M
authors.lastname: Takahashi
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Yamaguchi
authors.forename: Yohei
authors.initials: Y
authors.lastname: Okada
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Chiba
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D004220:Disulfides / Q000138:chemical synthesis* / Q000737:chemistry; D004563:Electrochemistry / Q000379:methods; D004566:Electrodes; D015394:Molecular Structure; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000596:Amino Acids; D004220:Disulfides; D010455:Peptides