title: Dechlorane Plus and its dechlorinated analogs from an e-waste recycling center in maternal serum and breast milk of women in Wenling, China.
abstract: We measured Dechlorane Plus (DP) and its dechlorinated analogs in the blood and milk from women living in e-waste recycling sites in Wenling of Taizhou region, China (n = 49). Both syn-DP and anti-DP were detected in all samples. Another compound, Cl(11)-DP, was detected in 45% and 84% of milk and serum samples, respectively. DP levels in blood and milk from residents living in the local environment >20 yrs (R(20) group) were significantly higher than those living in Taizhou <3 yrs (R(3) group) (p < 0.05). The milk/serum partition coefficient from the same women was approximately 0.43 and 0.47 for syn-DP and anti-DP, respectively. A similar value in milk compared with anti-DP/∑DPs (f(anti)) in serum suggested that stereoselective DP bio-accumulation did not occur during the DP transport from blood to milk. This result indicate that DP can bio-accumulate in blood and milk with the low milk/serum partition coefficient and similar blood and milk stereoselective bio-accumulation profiles.
authors.affiliation: State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center of Eco-Environment Sciences, The Chinese Academy of Sciences, PO Box 2871, 18 Shuangqing Road, Haidian District, Beijing 100085, People's Republic of China.
authors.forename: Yu-Jie
authors.initials: YJ
authors.lastname: Ben
authors.forename: Xing-Hong
authors.initials: XH
authors.lastname: Li
authors.forename: You-Lin
authors.initials: YL
authors.lastname: Yang
authors.forename: Long
authors.initials: L
authors.lastname: Li
authors.forename: Jun-Ping
authors.initials: JP
authors.lastname: Di
authors.forename: Wen-Yue
authors.initials: WY
authors.lastname: Wang
authors.forename: Ren-Fang
authors.initials: RF
authors.lastname: Zhou
authors.forename: Ke
authors.initials: K
authors.lastname: Xiao
authors.forename: Mei-Yun
authors.initials: MY
authors.lastname: Zheng
authors.forename: Yuan
authors.initials: Y
authors.lastname: Tian
authors.forename: Xiao-Bai
authors.initials: XB
authors.lastname: Xu
mesh_terms: D000328:Adult; D002681:China; D059029:Electronic Waste; D004781:Environmental Exposure / Q000706:statistics & numerical data*; D004785:Environmental Pollutants / Q000097:blood / Q000378:metabolism*; D005260:Female; D005411:Flame Retardants / Q000378:metabolism*; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000097:blood / Q000378:metabolism*; D008895:Milk, Human / Q000378:metabolism*; D009035:Mothers; D011083:Polycyclic Compounds / Q000097:blood / Q000378:metabolism*; D018505:Waste Management; D055815:Young Adult
chemical_list: D004785:Environmental Pollutants; D005411:Flame Retardants; D006843:Hydrocarbons, Chlorinated; D011083:Polycyclic Compounds; C526360:dechlorane plus