title: Inflammatory response attenuation in patients undergoing gasless laparoscopic gastrectomy.
abstract: OBJECTIVE
  It has been a matter of debate whether the advantage of gasless laparoscope setting is obvious when compared with the conventional operation. Thus, we compare the systemic response of proinflammatory markers and the adhesion molecules in serum levels after surgery between these two procedures.
  
  
  METHODS
  There were 23 patients in the gasless laparoscopy (GL) group, and 12 patients in the open surgery (OS) group.
  
  
  RESULTS
  The created wound length was smaller in the GL group (5.3±0.3cm vs. 8.9±0.5cm), the post operative recovery including the visual analog pain score on op day and day 1, flatus day, and hospital stay were also shown less in GL group. The levels of IL-6, IL-8 and ICAM were significantly lower in the GL group.
  
  
  CONCLUSIONS
  Immune response is less in gasless laparoscopy-assisted gastrectomy (GLAG) when compared with traditional approach, and the difference may have effects on the post operative recovery.
authors.affiliation: Department of General Surgery, National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Ming-Hsun
authors.initials: MH
authors.lastname: Wu
authors.forename: Ming-Yang
authors.initials: MY
authors.lastname: Wang
authors.forename: Ching-Yao
authors.initials: CY
authors.lastname: Yang
authors.forename: Po-Huang
authors.initials: PH
authors.lastname: Lee
authors.forename: Ming-Tsan
authors.initials: MT
authors.lastname: Lin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D016009:Chi-Square Distribution; D005260:Female; D005414:Flatulence / Q000209:etiology / Q000517:prevention & control; D005740:Gases; D005743:Gastrectomy / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D007249:Inflammation / Q000097:blood / Q000276:immunology / Q000517:prevention & control*; D018836:Inflammation Mediators / Q000097:blood; D018799:Intercellular Adhesion Molecule-1 / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D016209:Interleukin-8 / Q000097:blood; D010535:Laparoscopy / Q000009:adverse effects* / Q000379:methods; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000209:etiology / Q000517:prevention & control; D020127:Recovery of Function; D013274:Stomach Neoplasms / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; C508606:CXCL8 protein, human; D005740:Gases; C573420:ICAM1 protein, human; C508600:IL6 protein, human; D018836:Inflammation Mediators; D015850:Interleukin-6; D016209:Interleukin-8; D018799:Intercellular Adhesion Molecule-1