title: Management of renal dysfunction following term perinatal hypoxia-ischaemia.
abstract: Acute kidney injury frequently develops following the term perinatal hypoxia-ischaemia. Quantifying the degree of acute kidney injury is difficult, however, as the methods currently in use are suboptimal. Acute kidney injury management is largely supportive with little evidence basis for many interventions. This review discusses management strategies and novel biomarkers that may improve diagnosis and management of renal injury following perinatal hypoxia-ischaemia.
  
  
  CONCLUSIONS
  Following perinatal hypoxia-ischaemia, acute kidney injury is common. Management of neonatal acute kidney injury is largely supportive. Novel acute kidney injury biomarkers may play a role in optimizing new categorical definitions of renal injury. Studies are needed to investigate the impact of neonatal acute kidney injury on long-term outcome.
authors.affiliation: Neonatology, National Maternity Hospital, Dublin, Ireland. dee.sweetman@gmail.com
authors.forename: Deirdre U
authors.initials: DU
authors.lastname: Sweetman
authors.forename: Michael
authors.initials: M
authors.lastname: Riordan
authors.forename: Eleanor J
authors.initials: EJ
authors.lastname: Molloy
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D001238:Asphyxia Neonatorum / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D007231:Infant, Newborn