title: The impact and management of fibroids for fertility: an evidence-based approach.
abstract: Fibroids affect 35% to 77% of reproductive-age women. When selecting a treatment plan for symptomatic fibroids, the fibroid location, size, and number must be considered. Myomectomy remains the preferred method for women with fibroid-related infertility who wish to have children or maintain fertility. Currently available medical therapies reduce symptoms in the short term but may involve side effects when used long term. Initial fertility studies are encouraging but trials are needed. Recent medical advances have led to minimally invasive approaches for women with fibroid disease, but there is a strong demand for additional treatment options.
authors.affiliation: Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 10 Center Drive, Building 10 CRC 1-3140, MSC 1109, Bethesda, MD 20892-1109, USA.
authors.forename: Xiaoxiao Catherine
authors.initials: XC
authors.lastname: Guo
authors.forename: James H
authors.initials: JH
authors.lastname: Segars
mesh_terms: D004621:Embolization, Therapeutic / Q000379:methods; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D015907:Hysteroscopy / Q000379:methods; D007247:Infertility, Female / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D007889:Leiomyoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D009215:Myometrium / Q000601:surgery*; D011247:Pregnancy; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome; D063186:Uterine Myomectomy; D014594:Uterine Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D014599:Uterus / Q000098:blood supply*