title: A facile access to enantioenriched isoindolines via one-pot sequential Cu(I)-catalyzed asymmetric 1,3-dipolar cycloaddition/oxidation [corrected].
abstract: Facile access to enantioenriched isoindolines bearing a quaternary stereogenic center and a tertiary stereogenic center was successfully developed via highly efficient Cu(I)/(S,Rp)-PPFOMe-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylide with quinone derivatives followed by silica-gel-promoted oxidation [corrected] in a one-pot reaction protocol. The present catalytic system exhibited high diastereoselectivity, excellent enantioselectivity, and a broad substrate scope under mild conditions.
authors.affiliation: College of Chemistry and Molecular Sciences, Wuhan University, 430072, China.
authors.forename: Zhaolin
authors.initials: Z
authors.lastname: He
authors.forename: Tanglin
authors.initials: T
authors.lastname: Liu
authors.forename: Haiyan
authors.initials: H
authors.lastname: Tao
authors.forename: Chun-Jiang
authors.initials: CJ
authors.lastname: Wang