title: [Construction of multiple drug release system based on components of traditional Chinese medicine].
abstract: With the development of the modernization drive of traditional Chinese medicine (TCM) preparations, new-type TCM dosage forms research have become a hot spot in the field. Because of complexity of TCM components as well as uncertainty of material base, there is still not a scientific system for modern TCM dosage forms so far. Modern TCM preparations inevitably take the nature of the multi-component and the general function characteristics of multi-link and multi-target into account. The author suggests building a multiple drug release system for TCM using diverse preparation techniques and drug release methods at levels on the basis the nature and function characteristics of TCM components. This essay expounds elaborates the ideas to build the multiple traditional Chinese medicine release system, theoretical basis, preparation techniques and assessment system, current problems and solutions, in order to build a multiple TCM release system with a view of enhancing the bioavailability of TCM components and provide a new form for TCM preparations.
authors.affiliation: Key Laboratory of New Drug Delivery System of Chinese Meteria Medica, Jiangsu Provincial Academy of Chinese Medicine, Nanjing 210028, China. liudan0513@yeah.net
authors.forename: Dan
authors.initials: D
authors.lastname: Liu
authors.forename: Xiaobin
authors.initials: X
authors.lastname: Jia
authors.forename: Danhong
authors.initials: D
authors.lastname: Yu
authors.forename: Zhenhai
authors.initials: Z
authors.lastname: Zhang
authors.forename: E
authors.initials: E
authors.lastname: Sun
mesh_terms: D000818:Animals; D001682:Biological Availability; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D004304:Dosage Forms; D016503:Drug Delivery Systems / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000493:pharmacokinetics*; D006801:Humans; D008516:Medicine, Chinese Traditional
chemical_list: D004304:Dosage Forms; D004365:Drugs, Chinese Herbal