title: The case for launch of an international DNA-based birth cohort study.
abstract: The global health agenda beyond 2015 will inevitably need to broaden its focus from mortality reduction to the social determinants of deaths, growing inequities among children and mothers, and ensuring the sustainability of the progress made against the infectious diseases. New research tools, including technologies that enable high-throughput genetic and '-omics' research, could be deployed for better understanding of the aetiology of maternal and child health problems. The research needed to address those challenges will require conceptually different studies than those used in the past. It should be guided by stringent ethical frameworks related to the emerging collections of biological specimens and other health related information. We will aim to establish an international birth cohort which should assist low- and middle-income countries to use emerging genomic research technologies to address the main problems in maternal and child health, which are still major contributors to the burden of disease globally.
authors.affiliation: Centre for Population Health Sciences and Global Health Academy, University of Edinburgh, Scotland, UK ; Croatian Centre for Global Health, Faculty of Medicine, University of Split, Croatia.
authors.forename: Igor
authors.initials: I
authors.lastname: Rudan
authors.forename: Mickey
authors.initials: M
authors.lastname: Chopra
authors.forename: Yurii
authors.initials: Y
authors.lastname: Aulchenko
authors.forename: Abdullah H
authors.initials: AH
authors.lastname: Baqui
authors.forename: Zulfiqar A
authors.initials: ZA
authors.lastname: Bhutta
authors.forename: Karen
authors.initials: K
authors.lastname: Edmond
authors.forename: Bernardo L
authors.initials: BL
authors.lastname: Horta
authors.forename: Keith P
authors.initials: KP
authors.lastname: Klugman
authors.forename: Claudio F
authors.initials: CF
authors.lastname: Lanata
authors.forename: Shabir A
authors.initials: SA
authors.lastname: Madhi
authors.forename: Harish
authors.initials: H
authors.lastname: Nair
authors.forename: Zeshan
authors.initials: Z
authors.lastname: Qureshi
authors.forename: Craig
authors.initials: C
authors.lastname: Rubens
authors.forename: Evropi
authors.initials: E
authors.lastname: Theodoratou
authors.forename: Cesar G
authors.initials: CG
authors.lastname: Victora
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Martin W
authors.initials: MW
authors.lastname: Weber
authors.forename: James F
authors.initials: JF
authors.lastname: Wilson
authors.forename: Lina
authors.initials: L
authors.lastname: Zgaga
authors.forename: Harry
authors.initials: H
authors.lastname: Campbell