title: Mycoplasma hominis septic arthritis with concomitant gouty arthritis.
abstract: We report a rare case of Mycoplasma hominis septic arthritis occurring simultaneously with acute gout. A Taiwanese native aboriginal presented with right ankle swelling, erythema, local tenderness, and limitation of range of motion after a vertebroplasty. He had a history of gout without regular follow-up. Under the polarized light microscopy examination, his synovial fluid revealed neutrophilic leukocytosis and monosodium urate crystals. Subsequently, 2 consecutive anaerobic synovial fluid cultures yielded a cell wall-free microorganism, which was identified as M. hominis based on polymerase chain reaction of its 16S rDNA. He did not defervesce under colchicine and indomethacin treatment until we prescribed a doxycycline and moxifloxacin regimen. He responded well to 6-week doxycycline and moxifloxacin treatment without bone destruction and loss of joint function.
authors.affiliation: Division of Infectious Diseases, Departments of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
authors.forename: Ting-Shu
authors.initials: TS
authors.lastname: Wu
authors.forename: Kuang-Hui
authors.initials: KH
authors.lastname: Yu
authors.forename: An-Jing
authors.initials: AJ
authors.lastname: Kuo
authors.forename: Ju-Hsin
authors.initials: JH
authors.lastname: Chia
authors.forename: Shu-Chuan
authors.initials: SC
authors.lastname: Lu
authors.forename: Hsieh-Shong
authors.initials: HS
authors.lastname: Leu
authors.forename: Ching-Tai
authors.initials: CT
authors.lastname: Huang
mesh_terms: D000368:Aged; D000843:Ankle Joint / Q000382:microbiology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D015210:Arthritis, Gouty / Q000150:complications*; D001170:Arthritis, Infectious / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology*; D001372:Aza Compounds / Q000627:therapeutic use; D004318:Doxycycline / Q000627:therapeutic use; D024841:Fluoroquinolones; D006801:Humans; D008297:Male; D000077266:Moxifloxacin; D009175:Mycoplasma Infections / Q000175:diagnosis / Q000188:drug therapy; D019535:Mycoplasma hominis / Q000235:genetics; D016133:Polymerase Chain Reaction; D011804:Quinolines / Q000627:therapeutic use; D012336:RNA, Ribosomal, 16S / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D001372:Aza Compounds; D024841:Fluoroquinolones; D011804:Quinolines; D012336:RNA, Ribosomal, 16S; D004318:Doxycycline; D000077266:Moxifloxacin