title: Efficient synthesis of chiral 2,2'-bipyrrolidines by an anti-selective alkene diamination.
abstract: The rapid and efficient construction of complex chiral bicyclic amines is possible using a novel alkene diamination reaction. Electrophilic iodinating agents promote the intramolecular anti-selective diamination of alkenes and allow the efficient synthesis of chiral amines such as trans-bipyrrolidines.
authors.affiliation: Organisch-Chemisches Institut, Westfälische Wilhelms-Universität, Corrensstrasse 40, 48149 Münster, Germany.
authors.forename: Christian H
authors.initials: CH
authors.lastname: Müller
authors.forename: Roland
authors.initials: R
authors.lastname: Fröhlich
authors.forename: Constantin G
authors.initials: CG
authors.lastname: Daniliuc
authors.forename: Ulrich
authors.initials: U
authors.lastname: Hennecke
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003500:Cyclization; D015394:Molecular Structure; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D011759:Pyrrolidines