title: Is there a relationship between serum heart- type fatty acid binding protein level and clinical severity in patients with subarachnoid hemorrhage?
abstract: OBJECTIVE
  The aim of this study was to determine the serum heart-type fatty acid binding protein (H-FABP) levels and cardiac effects in patients presenting with subarachnoid hemorrhage (SAH) and to investigate whether any correlation exists between the cardiac effects and H-FABP.
  
  
  METHODS
  Forty-six patients diagnosed as acute SAH in the emergency department were included in this study. Twenty healthy adults were included in the study to serve as controls. Twelve-lead ECG was performed on all patients on admission. H-FABP levels of patients were determined in serum samples taken on admission.
  
  
  RESULTS
  Serum H-FABP levels of patients were found to be significantly higher than those of controls (p < 0.05). There was no significant correlation between serum H-FABP levels and ECG changes. There was a moderate positive correlation between H-FABP serum levels and the grade according to the Hunt and Hess classification (r=0.43, p < 0.05). There was a weak positive correlation between H-FABP serum levels and the grade according to the Fisher radiological classification (r=0.38, p < 0.05).
  
  
  CONCLUSIONS
  Serum H-FABP levels are increased in patients with SAH. Grades according to the Hunt and Hess and Fisher grading scales were shown to increase in conjunction with an increase in H-FABP levels.
authors.affiliation: Ondokuzmayis University, Faculty of Medicine, Department of Emergency, Samsun, Turkey.
authors.forename: Metehan
authors.initials: M
authors.lastname: Yilman
authors.forename: Cengiz
authors.initials: C
authors.lastname: Cokluk
authors.forename: Ahmet
authors.initials: A
authors.lastname: Baydin
authors.forename: Turker
authors.initials: T
authors.lastname: Yardan
authors.forename: Celal
authors.initials: C
authors.lastname: Kati
authors.forename: Murat
authors.initials: M
authors.lastname: Gunay
authors.forename: Murat
authors.initials: M
authors.lastname: Meric
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004562:Electrocardiography / Q000379:methods; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D013345:Subarachnoid Hemorrhage / Q000145:classification / Q000150:complications / Q000175:diagnosis*; D055815:Young Adult
chemical_list: C493408:FABP3 protein, human; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins