title: Liver tumor preparation in mice.
abstract: The liver is the most common site for distant metastasis of colorectal carcinomas. In this protocol, a liver tumor metastasis model is prepared by performing a splenic injection of tumor cells in mice. This model can be used to study the effect of host-tumor interactions on tumor biology and therapeutic response.
authors.forename: Rakesh K
authors.initials: RK
authors.lastname: Jain
authors.forename: Lance L
authors.initials: LL
authors.lastname: Munn
authors.forename: Dai
authors.initials: D
authors.lastname: Fukumura
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D008113:Liver Neoplasms / Q000473:pathology* / Q000556:secondary*; D051379:Mice; D009362:Neoplasm Metastasis / Q000473:pathology*