title: Synthesis of 2,6'-dioxo-1',5',6',7'-tetrahydrospiro[indoline-3,4'-pyrazolo[3,4-b]pyridine]-5'-carbonitriles via a one-pot, three-component reaction in water.
abstract: A one-pot, three-component condensation reaction of an isatin, aminopyrazole, and alkyl cyanoacetate in water to give 2,6'-dioxo-1',5',6',7'-tetrahydrospiro[indoline-3,4'-pyrazolo[3,4-b]pyridine]-5'-carbonitrile with good yields, at 90 °C, using a Et(3)N as catalyst, is described.
authors.affiliation: Department of Chemistry, University of Isfahan, Iran.
authors.forename: Abbas
authors.initials: A
authors.lastname: Rahmati
authors.forename: Tahmineh
authors.initials: T
authors.lastname: Kenarkoohi
authors.forename: Hamid Reza
authors.initials: HR
authors.lastname: Khavasi
mesh_terms: D000085:Acetates / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D007510:Isatin / Q000737:chemistry*; D015394:Molecular Structure; D011720:Pyrazoles / Q000737:chemistry*; D011728:Pyridones / Q000138:chemical synthesis* / Q000737:chemistry; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D014867:Water / Q000737:chemistry*
chemical_list: D000085:Acetates; D007211:Indoles; D011720:Pyrazoles; D011728:Pyridones; D013141:Spiro Compounds; D014867:Water; D007510:Isatin