title: Generic antiepileptic drug prescribing: a cross-sectional study.
abstract: The use of generic antiepileptic drugs (AEDs) in patients with epilepsy is controversial. The purpose of this study is to identify patient characteristics associated with increased odds of receiving a generic AED product. A large commercial database was used to identify patients with a primary diagnosis of epilepsy who were prescribed an AED during a three-month window. Data analysis found that those ≥65 years old had 15.7% greater odds of receiving a generic AED (OR = 1.157; 95% CI = 1.056-1.268). Patients with Medicaid were found to have 2.44 times the odds of having had a generic AED prescription (OR = 2.44; CI = 2.168-2.754). Patients residing in the Northeast had 12.6% decreased odds of receiving a generic AED (OR = 0.874; C I= 0.821-0.931). These patient characteristics could signify certain health care disparities and may represent potential confounders to future observational studies.
authors.affiliation: University of Kentucky College of Pharmacy, Lexington, KY, USA. JMeyer1686@gmail.com
authors.forename: Jennifer
authors.initials: J
authors.lastname: Meyer
authors.forename: David
authors.initials: D
authors.lastname: Fardo
authors.forename: Steven T
authors.initials: ST
authors.lastname: Fleming
authors.forename: Claudia
authors.initials: C
authors.lastname: Hopenhayn
authors.forename: Yevgeniya
authors.initials: Y
authors.lastname: Gokun
authors.forename: Melody
authors.initials: M
authors.lastname: Ryan
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D016568:Drugs, Generic / Q000627:therapeutic use*; D004827:Epilepsy / Q000188:drug therapy* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007341:Insurance; D019458:Insurance Coverage / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014481:United States / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000927:Anticonvulsants; D016568:Drugs, Generic