title: Solvent effects on Grubbs' pre-catalyst initiation rates.
abstract: Initiation rates for Grubbs and Grubbs-Hoveyda second generation pre-catalysts have been measured accurately in a range of solvents. Solvatochromic fitting reveals different dependencies on key solvent parameters for the two pre-catalysts, consistent with different mechanisms by which the Grubbs and Grubbs-Hoveyda pre-catalysts initiate.
authors.affiliation: Global Research and Development, AstraZeneca, Silk Road Business Park, Charter Way, Macclesfield, SK10 2NA, UK.
authors.forename: Ian W
authors.initials: IW
authors.lastname: Ashworth
authors.forename: David J
authors.initials: DJ
authors.lastname: Nelson
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Percy
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry; D012997:Solvents / Q000737:chemistry*
chemical_list: D000475:Alkenes; D056831:Coordination Complexes; D012997:Solvents; D012428:Ruthenium