title: [An atypical presentation of Kikuchi-Fujimoto disease].
abstract: BACKGROUND
  Histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease) is a rare clinical entity characterized by the association of enlarged lymph nodes in the posterior cervical region and fever. The disease is more frequent in young women.
  
  
  METHODS
  We report a 41-year-old African patient who presented with atypical features of Kikuchi's disease including cutaneous lupus, haemophagocytosis, and lymphocytic meningitis. The ethnic origin and the clinical presentation were initially suggestive of tuberculous meningitis. However, microbiological analyses remained negative, histological findings were suggestive of Kikuchi's disease and HHV6 DNA integration was documented in our patient.
  
  
  CONCLUSIONS
  Kikuchi's disease should be suspected in an African patient when lymphocytic meningitis is associated with enlarged cervical lymph nodes, hemophagocytosis and HHV6 DNA integration.
authors.affiliation: Service de médecine interne A, hôpital Lariboisière, université Paris Cité-Diderot, AP-HP, 2, rue Ambroise-Paré, 75010 Paris, France. menicecile@gmail.com
authors.forename: C
authors.initials: C
authors.lastname: Méni
authors.forename: A
authors.initials: A
authors.lastname: Chabrol
authors.forename: M
authors.initials: M
authors.lastname: Wassef
authors.forename: A
authors.initials: A
authors.lastname: Gautheret-Dejean
authors.forename: J-F
authors.initials: JF
authors.lastname: Bergmann
authors.forename: S
authors.initials: S
authors.lastname: Mouly
mesh_terms: D000328:Adult; D044383:Black People; D003937:Diagnosis, Differential; D020042:Histiocytic Necrotizing Lymphadenitis / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D009333:Neck