title: Pigment dispersion glaucoma induced by the chafing effect of intraocular lens haptics in Asian eyes.
abstract: OBJECTIVE
  To study the possible mechanism and treatment for pigment dispersion glaucoma (PDG) caused by single-piece acrylic (SPA) intraocular lens (IOL) ciliary sulcus fixation in Asian eyes.
  
  
  METHODS
  Patients referred for PDG caused by SPA IOL ciliary sulcus fixation to our hospital from April 2005 to June 2011 were included. The patients' general information, IOL type, interval between initial surgery and PDG occurrence, examination findings, antiglaucoma medicine regimen and surgical interventions were recorded.
  
  
  RESULTS
  In total, six eyes from five Chinese patients were included in this study. The intraocular pressure (IOP) increased 19-30 days after cataract surgery and was not satisfactorily controlled with antiglaucoma medication. Dense pigmentation was deposited on the IOLs and on the anterior chamber angle. IOL haptic chafing was noted on the rear iris surface. IOL repositioning in the capsular bag was performed in three eyes and was combined with trabeculectomy in two eyes with progressive glaucoma. An IOL exchange with three-piece IOL ciliary sulcus fixation was performed in the other three eyes. Scanning electron microscopy of the explanted IOLs demonstrated a rough edge on the IOL haptics.
  
  
  CONCLUSIONS
  SPA IOLs were not suitable for ciliary sulcus fixation. The chafing effect of the IOL haptics on the posterior iris pigment epithelium could induce PDG in Asian eyes. IOLs should be positioned in the capsular bag or a three-piece IOL should be used instead.
authors.affiliation: Department of Opthamology, Peking University Third Hospital, Beijing, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Hong
authors.forename: Yan-Xiu
authors.initials: YX
authors.lastname: Sun
authors.forename: Hong
authors.initials: H
authors.lastname: Qi
authors.forename: Ji-Chao
authors.initials: JC
authors.lastname: Zhou
authors.forename: Yan-Sheng
authors.initials: YS
authors.lastname: Hao
mesh_terms: D000180:Acrylic Resins; D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D044466:Asian People; D002387:Cataract Extraction; D002924:Ciliary Body / Q000293:injuries* / Q000601:surgery; D020878:Device Removal; D017889:Exfoliation Syndrome / Q000208:ethnology / Q000209:etiology* / Q000628:therapy; D005131:Eye Injuries / Q000208:ethnology / Q000209:etiology* / Q000628:therapy; D005260:Female; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012189:Retrospective Studies; D014130:Trabeculectomy; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult
chemical_list: D000180:Acrylic Resins; D000959:Antihypertensive Agents