title: [Effectiveness of vertebroplasty in painful chronic osteoporotic vertebral fractures. A report of 5 patients].
abstract: OBJECTIVE
  Percutaneous vertebroplasty (PVP) has been successfully used in the treatment of pain related to osteoporotic vertebral fractures refractory to medical therapy, especially in the treatment of acute factures. However, the effectiveness of this therapeutic approach in the treatment of painful chronic vertebral fractures is less clear.
  
  
  METHODS
  In this report we evaluate the short and long-term effectiveness in pain relief of PVP in a group of 5 patients with pain related to chronic osteoporotic vertebral fractures without bone marrow edema (BME) on magnetic resonance imaging (MRI). All patients were followed during one year, assessing analgesic use, pain evolution (on a 10-point visual analog scale [VAS]), new vertebral fractures and other clinical complications. Seven procedures were performed in the 5 patients.
  
  
  RESULTS
  All patients reported substantial improvement in back pain 2 weeks after the procedure, with a mean decrease of 53% in the VAS. However, one year after PVP most patients (4 out 5) worsened, achieving similar VAS scores to those obtained at baseline. No additional vertebral fractures or other clinical complications were observed.
  
  
  CONCLUSIONS
  The present cases suggest that the long-term effectiveness of PVP in the treatment of painful chronic vertebral fractures without BME on MRI is scarce.
authors.affiliation: Servicio de Reumatología, Hospital Clínic, Universidad de Barcelona, Barcelona, España.
authors.forename: Angels
authors.initials: A
authors.lastname: Martínez-Ferrer
authors.forename: Jordi
authors.initials: J
authors.lastname: Blasco
authors.forename: Núria
authors.initials: N
authors.lastname: Guañabens
authors.forename: Jaume
authors.initials: J
authors.lastname: Pomés
authors.forename: Pilar
authors.initials: P
authors.lastname: Peris
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D000700:Analgesics / Q000627:therapeutic use; D001416:Back Pain / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D001843:Bone Cements; D050071:Bone Density Conservation Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D005598:Fractures, Spontaneous / Q000209:etiology / Q000601:surgery*; D006391:Hemangioma / Q000150:complications; D006801:Humans; D008159:Lumbar Vertebrae / Q000293:injuries / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications* / Q000188:drug therapy; D059408:Pain Management; D010147:Pain Measurement; D016103:Spinal Fractures / Q000209:etiology / Q000601:surgery*; D013904:Thoracic Vertebrae / Q000293:injuries / Q000601:surgery*; D054854:Vertebroplasty / Q000379:methods
chemical_list: D000700:Analgesics; D001843:Bone Cements; D050071:Bone Density Conservation Agents