title: Self-reported assessment of health-related quality of life in children who underwent restorative proctocolectomy with ileal J-pouch anal anastomosis for ulcerative colitis.
abstract: OBJECTIVE
  To clarify health-related quality of life (HRQOL) by self-evaluation after restorative proctocolectomy with ileal J-pouch anal anastomosis (IPAA) in children with ulcerative colitis, a questionnaire using the Pediatric Quality of Life Inventory™ 4.0 (PedsQL) was administered.
  
  
  METHODS
  The PedsQL was administered to 13 consecutive children (mean age 14.5 years) who underwent IPAA between 2005 and 2010 in our hospital and age-matched healthy controls. The mean duration after IPAA was 2.5 years (range 0.08-6 years) at the time of this study. Healthy children completed the same questionnaire by retrospective imaging during the past 1 month by the PedsQL evaluation policy.
  
  
  RESULTS
  Patients' total score and each functioning score after IPAA reached the same levels as those in healthy controls. Soiling, pouchitis occurrence, and bowel movements had no significant relationship to the PedsQL total score and each functioning score.
  
  
  CONCLUSIONS
  Interference of physical activity, emotional status, and social life caused by refractory ulcerative colitis (UC) worsens patients' HRQOL. IPAA could resolve these problems in children with UC and result in an HRQOL comparable with that in healthy children.
authors.affiliation: Department of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan. ucchie@clin.medic.mie-u.ac.jp
authors.forename: Keiichi
authors.initials: K
authors.lastname: Uchida
authors.forename: Ayumi
authors.initials: A
authors.lastname: Kawamata
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Hashimoto
authors.forename: Mikihiro
authors.initials: M
authors.lastname: Inoue
authors.forename: Kohei
authors.initials: K
authors.lastname: Otake
authors.forename: Yuhki
authors.initials: Y
authors.lastname: Koike
authors.forename: Kohei
authors.initials: K
authors.lastname: Matsushita
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Fujikawa
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Okita
authors.forename: Toshimitsu
authors.initials: T
authors.lastname: Araki
authors.forename: Kouji
authors.initials: K
authors.lastname: Tanaka
authors.forename: Masato
authors.initials: M
authors.lastname: Kusunoki
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D003093:Colitis, Ulcerative / Q000601:surgery*; D039021:Colonic Pouches; D005260:Female; D006801:Humans; D008297:Male; D016737:Proctocolectomy, Restorative; D011788:Quality of Life; D057566:Self Report; D011795:Surveys and Questionnaires