title: Identification of the MICA*070 allele by sequencing and phasing.
abstract: A novel MICA allele, MICA*070, was defined by sequencing. The new allele differs from the MICA*008:04 sequence in exon 2, encoding a C instead of G corresponding to cDNA nucleotide position 183. This nucleotide substitution is predicted to encode serine instead of arginine at residue 38 of the α1 domain of the MICA molecule.
authors.affiliation: Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
authors.forename: D
authors.initials: D
authors.lastname: Moran
authors.forename: S
authors.initials: S
authors.lastname: Morishima
authors.forename: M
authors.initials: M
authors.lastname: Malkki
authors.forename: E W
authors.initials: EW
authors.lastname: Petersdorf
mesh_terms: D000483:Alleles; D001483:Base Sequence; D005091:Exons / Q000235:genetics*; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D015203:Reproducibility of Results; D017422:Sequence Analysis, DNA / Q000379:methods*; D012689:Sequence Homology, Nucleic Acid
chemical_list: D015395:Histocompatibility Antigens Class I; C099187:MHC class I-related chain A