title: [Rapid determination of pesticide multiresidues in vegetables and fruits by accelerated solvent extraction coupled with online gel permeation chromatography-gas chromatography-mass spectrometry].
abstract: A novel method was developed for the rapid determination of 22 representative pesticide residues in vegetables and fruits based on accelerated solvent extraction (ASE) coupled with online gel permeation chromatography-gas chromatography-mass spectrometry (GPC-GC-MS). The sample was extracted by accelerated solvent extraction with dichloromethane-acetone (1:1, v/v) and purified with a carbon/NH2 column, evaporated to dryness by nitrogen, then dissolved in cyclohexane-acetone (7:3, v/v), and finally identified and quantified by GPC-GC-MS system in selected ion monitoring (SIM) mode. The results showed that the linearities of the 22 pesticides were good in their linear ranges. The limits of detection (S/N = 3) were 0.3-1.8 microg/kg. The limits of quantification (S/N = 10) ranged from 1-6 microg/kg. The recoveries for all at three spiked levels in Chinese cabbages and apples ranged from 70.5% to 107.5% with the relative standard deviations (RSDs) of 2.1%-8.7%. The proposed method is accurate, sensitive and highly efficient in the extraction, and can be used for the quick determination of the pesticide multiresidues in vegetables and fruits.
authors.affiliation: Changzhou Center for Disease Control and Prevention, Changzhou 213022, China. ouyang1016@126.com
authors.forename: Yunfu
authors.initials: Y
authors.lastname: Ouyang
authors.forename: Hongbing
authors.initials: H
authors.lastname: Tang
authors.forename: Ying
authors.initials: Y
authors.lastname: Wu
authors.forename: Guiying
authors.initials: G
authors.lastname: Li
mesh_terms: D005591:Chemical Fractionation; D002850:Chromatography, Gel / Q000379:methods*; D005506:Food Contamination / Q000032:analysis; D005638:Fruit / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D010573:Pesticide Residues / Q000032:analysis*; D012997:Solvents; D014675:Vegetables / Q000737:chemistry*
chemical_list: D010573:Pesticide Residues; D012997:Solvents