title: Synthesis of some new 2,3-disubstituted-4(3H)quinazolinone derivatives.
abstract: Quinazolinones are interesting materials because of their valuable biological effects. In this study some new 2,3-disubstituted-4(3H)quinqzolinone derivatives were synthesized from anthranilic acid in six steps by introducing a new chiral center to the aliphatic side chain of the quinazolinone. In the last step, a single acylation on the hydrazine moiety afforded final compounds. The structures of compounds were confirmed by IR, (1)HNMR and Mass spectra.
authors.affiliation: Department of Medicinal Chemistry and Isfahan Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Science, Isfahan University of Medical Sciences, Isfahan, I.R.Iran.
authors.forename: F
authors.initials: F
authors.lastname: Hassanzadeh
authors.forename: M Rahmani
authors.initials: MR
authors.lastname: Khajouei
authors.forename: G H
authors.initials: GH
authors.lastname: Hakimelahi
authors.forename: E
authors.initials: E
authors.lastname: Jafari
authors.forename: G A
authors.initials: GA
authors.lastname: Khodarahmi