title: The clinical characteristics and treatment outcomes of patients with ruptured middle cerebral artery aneurysms associated with intracerebral hematoma.
abstract: OBJECTIVE
  The objective of this study is to evaluate the clinical presentation and outcomes of patients with an intracerebral hematoma (ICH) associated with a ruptured middle cerebral artery (MCA) aneurysm, and the correlation factors associated with the aneurysm and characteristics of the hematoma.
  
  
  METHODS
  A retrospective evaluation of clinical and radiologic characteristics and outcomes was conducted for 24 patients (11 men and 13 women; mean age, 53 years) with ruptured MCA aneurysms associated with ICH between September 2008 and December 2011.
  
  
  RESULTS
  Thirteen (54%) of the 24 patients had a favorable outcome, four (17%) suffered from severe disability, and seven (29%) died. Based on Hunt and Hess grade, one patient was classified as Grade II, three as Grade III, 12 as Grade IV, and eight as Grade V. Patients with an unfavorable outcome had significantly larger aneurysms (p = 0.047) and ICH volumes (p = 0.002), compared with patients in the group with a favorable outcome. The most frequent rupture point of aneurysms was the lateral aspect of the aneurysm (54.2%). When the rupture point is toward the lateral direction, the distribution of ICH tended to be located at the temporal lobe and intrasylvian.
  
  
  CONCLUSIONS
  Results of the present study suggest an association of the initial clinical state, the size of the aneurysm, and ICH volume with outcome. Although no difference was observed between the location of the rupture point and patient outcomes, an accurate assessment of ICH patterns and the rupture point in angiography may help to ensure surgical exposure and a safe aneurysm clipping.
authors.affiliation: Department of Neurosurgery, Ajou University Hospital, School of Medicine, Ajou University, Suwon, Korea.
authors.forename: Chang Sun
authors.initials: CS
authors.lastname: Lee
authors.forename: Jeong Un
authors.initials: JU
authors.lastname: Park
authors.forename: Jae Gyu
authors.initials: JG
authors.lastname: Kang
authors.forename: Yong Cheol
authors.initials: YC
authors.lastname: Lim