title: Myxoid chondrosarcoma of sphenoid bone.
abstract: The myxoid variant of chondrosarcoma is usually seen in soft tissues where it is known as chordoid sarcoma or parachordoma. Rarely, it involves bone and when it does, cranial bones are the preferred location. This tumor is frequently amalgamated with the chondroid variant of chordoma, especially when the lesion occurs in the sphenoid bone/spheno-occipital region, because of their similar clinical presentations, anatomical locations, radiological findings, and mistaken histopathological features. It is essential to distinguish myxoid chondrosarcoma from the chondroid variant of chordoma, because of the different treatment protocol and prognostic importance. We present such a location-based diagnostic dilemma, solved successfully with ancillary immunohistochemistry.
authors.affiliation: Department of Pathology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
authors.forename: Amit K
authors.initials: AK
authors.lastname: Chowhan
authors.forename: Nandyala
authors.initials: N
authors.lastname: Rukmangadha
authors.forename: Rashmi
authors.initials: R
authors.lastname: Patnayak
authors.forename: Chandra Mouliswara Prasad
authors.initials: CM
authors.lastname: Bodapati
authors.forename: Vijaya Laxmi
authors.initials: VL
authors.lastname: Bodagala
authors.forename: Mandyam Kumaraswamy
authors.initials: MK
authors.lastname: Reddy