title: An advanced monitoring platform for rational design of recombinant processes.
abstract: Bioprocess engineering is an application-oriented science in an interdisciplinary environment, and a meaningful combination of different scientific disciplines is the only way to meet the challenges of bioprocess complexity. Setting up a reasoned process monitoring platform is the first step in an iterative procedure aiming at process and systems understanding, being the key to rational and innovative bioprocess design. This chapter describes a comprehensive process monitoring platform and how the resulting knowledge is translated into new strategies in process and/or host cell design.
authors.affiliation: Department of Biotechnology, University of Natural Resources and Life Sciences, Muthgasse 18/B, A-1190, Vienna, Austria, gerald.striedner@boku.ac.at.
authors.forename: G
authors.initials: G
authors.lastname: Striedner
authors.forename: K
authors.initials: K
authors.lastname: Bayer
mesh_terms: D057005:Bioengineering / Q000295:instrumentation* / Q000379:methods*; D018533:Biomass; D004777:Environment; D011994:Recombinant Proteins / Q000276:immunology* / Q000378:metabolism*; D012107:Research Design
chemical_list: D011994:Recombinant Proteins