title: A randomized, single-center study of equivalence of 2 intraocular lenses used in cataract surgery.
abstract: OBJECTIVE
  To compare the outcomes of 2 intraocular lenses (IOLs) for the treatment of age-related cataracts.
  
  
  METHODS
  Prospective, randomized trial.
  
  
  METHODS
  Patients with age-related cataracts were recruited and randomized to receive phacoemulsification and implantation of either the AcrySof SA60AT lens (Alcon, Inc, Fort Worth, TX) or the low-cost Tecsoft Flex lens (Fred Hollows Foundation, Tilganga, Nepal). A total of 300 patients were available for description and analysis (148 in the AcrySof group and 152 in the Tecsoft group).
  
  
  METHODS
  Patients underwent phacoemulsification and implantation of the AcrySof SA60AT lens or the Tecsoft Flex lens. They were followed up and examined at baseline, 1 week, 1 month, 6 months, and 12 months after cataract surgery.
  
  
  METHODS
  Uncorrected distance visual acuity (UDVA), best-corrected distance visual acuity (BDVA), incidence of posterior capsule opacification (PCO), Visual Function Index questionnaire results, and safety of the implanted IOLs.
  
  
  RESULTS
  No significant difference (P>0.05) was found in UDVA and BDVA after surgery between the 2 groups. The equivalence test of the 95% confidence intervals showed that both lenses had an equal improvement of UDVA and BDVA as well as similar rates of PCO after cataract surgery. There was no significant difference between the 2 groups with regard to visual functioning or the incidence of adverse surgical events during (P>0.05) or after (P>0.05) the surgery.
  
  
  CONCLUSIONS
  The Tecsoft Flex IOL is a low-cost suitable alternative that is similar to the AcrySof IOL in terms of safety and visual outcomes.
authors.affiliation: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Victoria, Australia.
authors.forename: Marios
authors.initials: M
authors.lastname: Constantinou
authors.affiliation: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Victoria, Australia; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong.
authors.forename: Vishal
authors.initials: V
authors.lastname: Jhanji
authors.affiliation: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Victoria, Australia.
authors.forename: Xie
authors.initials: X
authors.lastname: Jing
authors.affiliation: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Victoria, Australia; Singapore Eye Research Institute, National University of Singapore, Singapore, Republic of Singapore.
authors.forename: Ecosse L
authors.initials: EL
authors.lastname: Lamoureux
authors.affiliation: BUPA, Hawthorn VIC, Australia.
authors.forename: Umberto
authors.initials: U
authors.lastname: Boffa
authors.affiliation: Melbourne School of Population Health, University of Melbourne, Melbourne, Australia.
authors.forename: Hugh R
authors.initials: HR
authors.lastname: Taylor
authors.affiliation: Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Victoria, Australia; Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. Electronic address: rasikv@unimelb.edu.au.
authors.forename: Rasik B
authors.initials: RB
authors.lastname: Vajpayee
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology; D001672:Biocompatible Materials; D058442:Capsule Opacification / Q000209:etiology; D002386:Cataract / Q000503:physiopathology / Q000534:rehabilitation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D018918:Phacoemulsification; D057852:Posterior Capsule of the Lens / Q000473:pathology; D011446:Prospective Studies; D011474:Prosthesis Design; D011788:Quality of Life; D012029:Refraction, Ocular / Q000502:physiology; D018434:Sickness Impact Profile; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D019987:Persons with Visual Disabilities / Q000534:rehabilitation
chemical_list: D001672:Biocompatible Materials