title: [Experience of contemporary treatment of radiation burns in individuals subjected to ionizing radiation].
abstract: The article presents new approach to treatment of radiation disorders presenting as indolent ulcers. The approach is based on autologous multipotent mesenchimal stromal cells applied locally and injected around the injuried zone. The ulcers heal due to the fact that the transplanted cells stimulate local regeneration processes, angiogenesis, ceased inflammation and apoptosis. The method is a new medical technology based on vast preclinical studies and could be put into medical practice.
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Bushmanov
authors.forename: I I
authors.initials: II
authors.lastname: Eremin
authors.forename: B B
authors.initials: BB
authors.lastname: Moroz
authors.forename: I A
authors.initials: IA
authors.lastname: Galstian
authors.forename: N M
authors.initials: NM
authors.lastname: Nadezhina
authors.forename: T S
authors.initials: TS
authors.lastname: Slobodina
authors.forename: O S
authors.initials: OS
authors.lastname: Grinakovskaia
mesh_terms: D000368:Aged; D004351:Drug Resistance; D005260:Female; D005720:Gamma Rays / Q000009:adverse effects*; D006801:Humans; D008297:Male; D045164:Mesenchymal Stem Cell Transplantation / Q000379:methods*; D008875:Middle Aged; D039902:Multipotent Stem Cells / Q000637:transplantation*; D018919:Neovascularization, Physiologic; D011829:Radiation Dosage; D011855:Radiodermatitis / Q000503:physiopathology / Q000628:therapy; D012038:Regeneration; D012720:Severity of Illness Index; D012867:Skin / Q000528:radiation effects; D012883:Skin Ulcer / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D035703:Therapies, Investigational / Q000379:methods; D014182:Transplantation, Autologous / Q000379:methods; D016896:Treatment Outcome