title: Primary high-grade serous carcinoma arising in the urethra or urethral diverticulum: a report of 2 cases of an extremely rare phenomenon.
abstract: Serous carcinomas most commonly arise within the uterine corpus or ovary/fallopian tube, but there are 2 prior case reports of primary vaginal serous carcinoma. We report 2 examples of high-grade serous carcinoma arising within the urethra or a urethral diverticulum (1 case each). Both neoplasms exhibited the classic morphologic features of high-grade serous carcinoma, and a combination of clinical, radiologic, and pathologic examination excluded other possible sites of primary neoplasm.
authors.affiliation: Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland.
authors.forename: Ciaran
authors.initials: C
authors.lastname: Flynn
authors.forename: Jon
authors.initials: J
authors.lastname: Oxley
authors.forename: Paul
authors.initials: P
authors.lastname: McCullagh
authors.forename: W Glenn
authors.initials: WG
authors.lastname: McCluggage
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018284:Cystadenocarcinoma, Serous / Q000473:pathology*; D005260:Female; D006801:Humans; D060787:Neoplasm Grading; D014523:Urethral Neoplasms / Q000473:pathology*