title: Prognostic factors in gastric carcinoma after R0 resection with DII lymph node dissection. Tunisian experience.
abstract: BACKGROUND
  Curative resection with adequate lymph node dissection is the treatment of choice for gastric cancer.
  
  
  OBJECTIVE
  To determine the prognostic factors after R0 resection with DII lymph node dissection.
  
  
  METHODS
  We retrospectively assessed 126 patients who underwent R0 resection with DII lymph node dissection for gastric cancer (excluding the upper third of the stomach) in a single institution between 1991 and 2006 with median follow-up of 38.5 months (6 - 219). Prognostic factors were assessed by Cox proportional hazard model.
  
  
  RESULTS
  There were 45 women and 81 men. The median age was 60 years (21 - 87). Four patients died (3.2 %). Postoperative hospital morbidity was 16.7 %. The pathologic review of the slides revealed that 50% of the tumors were stage T3 (63 cases). The median number of lymph node removed was 11 (8-40), 50% were involved. Five and 10 years survival rates were respectively 56.9 % and 40.2 %. In multivariable analysis, depth of wall invasion, lymph node involvement and more than 15 retrieved lymph nodes were found to be independent prognosis factors.
  
  
  CONCLUSIONS
  After R0 resection with DII lymphadenectomy, depth of wall invasion, lymph node involvement and more than 15 retrieved lymph nodes were independent predictive factors for survival.
authors.affiliation: Department of General Surgery, Rabta Hospital, Tunis, Tunisia.
authors.forename: Sofiene
authors.initials: S
authors.lastname: Ayadi
authors.forename: Amine
authors.initials: A
authors.lastname: Daghfous
authors.forename: Amine
authors.initials: A
authors.lastname: Makni
authors.forename: Fadhel
authors.initials: F
authors.lastname: Fteriche
authors.forename: Houcine
authors.initials: H
authors.lastname: Maghrebi
authors.forename: Wael
authors.initials: W
authors.lastname: Rebai
authors.forename: Heykal
authors.initials: H
authors.lastname: Bedioui
authors.forename: Faouzi
authors.initials: F
authors.lastname: Chebbi
authors.forename: Rachid
authors.initials: R
authors.lastname: Ksantini
authors.forename: Adel
authors.initials: A
authors.lastname: Ammous
authors.forename: Mohamed
authors.initials: M
authors.lastname: Jouini
authors.forename: Montassar
authors.initials: M
authors.lastname: Kacem
authors.forename: Zoubeir
authors.initials: Z
authors.lastname: Ben Safta
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016019:Survival Analysis; D055815:Young Adult