title: Performance of Eudragit coated whispering gallery mode resonator-based immunosensors.
abstract: Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit®L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution.
authors.affiliation: Istituto di Fisica Applicata Nello Carrara (IFAC CNR), 50019 Sesto Fiorentino, Firenze, Italy. a.giannetti@ifac.cnr.it
authors.forename: Ambra
authors.initials: A
authors.lastname: Giannetti
authors.forename: Simone
authors.initials: S
authors.lastname: Berneschi
authors.forename: Francesco
authors.initials: F
authors.lastname: Baldini
authors.forename: Franco
authors.initials: F
authors.lastname: Cosi
authors.forename: Gualtiero Nunzi
authors.initials: GN
authors.lastname: Conti
authors.forename: Silvia
authors.initials: S
authors.lastname: Soria
mesh_terms: D015374:Biosensing Techniques; D008856:Microscopy, Fluorescence; D008863:Microspheres; D011109:Polymethacrylic Acids / Q000737:chemistry*
chemical_list: D011109:Polymethacrylic Acids; C038300:methylmethacrylate-methacrylic acid copolymer