title: Sonographically guided vacuum-assisted breast biopsy for complete excision of presumed benign breast lesions.
abstract: OBJECTIVE
  Benign breast disease has a high prevalence and a substantial impact on women's quality of life. Excisional biopsy is still frequently used for the diagnosis of breast masses in China. We report our experience with percutaneous removal of presumed benign lesions under sonographic guidance with a multidirectional handheld vacuum-assisted biopsy device and evaluate this procedure as an alternative approach in the diagnosis and treatment of clinically benign breast lesions.
  
  
  METHODS
  A total of 1766 sonographically guided vacuum-assisted excision procedures were performed on 738 patients with clinically benign breast lesions between February 2008 and October 2011.
  
  
  RESULTS
  The mean patient age ± SD was 35.86 ± 11.2 years. The mean diameter of the lesions was 1.25 ± 0.70 cm. The mean number of cores needed to achieve removal was 11.6 ± 4.8. Fifty-nine percent of cases (436 of 738) had multiple breast lesions. There were no serious adverse events. There were only 37 cases with substantial bleeding. No cases had wound infection. Hematoma occurred in 62 cases (8%), but none needed surgical intervention. Skin damage occurred in only 5 cases (0.7%) and 14 cases (1.9%) had a vasovagal response. Most of the specimens (1755 of 1766 [99.4%]) were benign. Postoperative pain was minimal, and better cosmetic results were obtained than with conventional open biopsy.
  
  
  CONCLUSIONS
  Percutaneous excisional biopsy with a sonographically guided vacuum-assisted core device is a safe and effective approach for accurate diagnosis and complete removal of presumed benign breast masses.
authors.affiliation: Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, 430060 Wuhan, Hubei, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Yao
authors.forename: Juanjuan
authors.initials: J
authors.lastname: Li
authors.forename: Yinwen
authors.initials: Y
authors.lastname: Wan
authors.forename: Yunping
authors.initials: Y
authors.lastname: Zhong
authors.forename: Wen
authors.initials: W
authors.lastname: Wei
authors.forename: Yi
authors.initials: Y
authors.lastname: Tu
authors.forename: Hexiang
authors.initials: H
authors.lastname: Tong
authors.forename: Shengrong
authors.initials: S
authors.lastname: Sun
mesh_terms: D000328:Adult; D001707:Biopsy, Needle / Q000379:methods*; D001941:Breast Diseases / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D061705:Image-Guided Biopsy; D018084:Ultrasonography, Interventional; D014618:Vacuum