title: [Aicardi syndrome with unilateral ocular involvement].
abstract: BACKGROUND
  Aicardi syndrome is a severe congenital disorder affecting females and characterized by a triad of symptoms, including infantile spasms, agenesis of the corpus callosum and chorioretinal lacunae.
  
  
  METHODS
  This retrospective study demonstrates that three out of eight children followed at CHRU of Lille for Aicardi syndrome exhibited unilateral chorioretinal lacunae. For these patients, the condition was diagnosed prior to 6months based on abnormal fundus exam as well as neurological and radiological (MRI) abnormalities.
  
  
  CONCLUSIONS
  These patients with Aicardi syndrome have unilateral ocular abnormalities. Moreover, the differential diagnosis must be considered in the presence of microcephaly, chorioretinal dysplasia and mental retardation.
  
  
  CONCLUSIONS
  Unilateral chorioretinal lacunae do not rule out the diagnosis of Aicardi syndrome in the presence of psychomotor retardation and agenesis of the corpus callosum on magnetic resonance imaging.
authors.affiliation: Service d'explorations fonctionnelles de la vision, hôpital Roger-Salengro, CHRU de Lille, rue du Professeur-Émile-Laine, 59037 Lille cedex, France. aurtabary@yahoo.fr
authors.forename: A
authors.initials: A
authors.lastname: Tabary
authors.forename: V
authors.initials: V
authors.lastname: Vangheluwe
authors.forename: S
authors.initials: S
authors.lastname: Defoort-Dhellemmes
authors.forename: I
authors.initials: I
authors.lastname: Drumare-Bouvet
mesh_terms: D000293:Adolescent; D058540:Aicardi Syndrome / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging; D002675:Child, Preschool; D005128:Eye Diseases / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D011859:Radiography; D012189:Retrospective Studies