title: Antimycobacterial crude plant extracts from South, Central, and North America.
abstract: Two-hundred and thirty crude organic extracts from 118 plant species distributed among 10 families were evaluated for anti-mycobacterial activity. Activity was determined against Mycobacterium tuberculosis H(37)Rv and Mycobacterium avium using the BACTEC 460 radiorespirometric assay. At 100 μg/ml, twenty-four and ten of the extracts caused more than 95% inhibition of growth of M. tuberculosis and M. avium, respectively. The most active plant species (100% inhibition) were Borrichia frutescens, Solidago arguta, and Inula helenium against M. tuberculosis, Euthamia leptocephala against M. avium, and Erigeron strigosus and Magnolia acuminata against both mycobacteria.
authors.affiliation: Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana, U.S.A.
authors.forename: C L
authors.initials: CL
authors.lastname: Cantrell
authors.forename: N H
authors.initials: NH
authors.lastname: Fischer
authors.forename: L
authors.initials: L
authors.lastname: Urbatsch
authors.forename: M S
authors.initials: MS
authors.lastname: McGuire
authors.forename: S G
authors.initials: SG
authors.lastname: Franzblau