title: Adenosquamous carcinoma of the uncinate process of the pancreas with synchronous gastrointestinal stromal tumor of the stomach: Case report and review of the literature.
abstract: Recently, the coexistence of gastrointestinal stromal tumors (GISTs) with other neoplasms has been studied with increasing frequency. Coexistence of pancreatic cancer with GISTs remains a rarity; however, here, we report a very rare case of adenosquamous carcinoma (ASC) of the uncinate process of the pancreas with synchronous GISTs of the stomach in a 62-year-old female. The patient presented with epigastric discomfort and vomiting. Radiographic imaging revealed two masses; one located at the body of the stomach and the other located at the uncinate process of the pancreas. Intraoperatively, a fine needle aspiration biopsy was conducted in the uncinate process of the pancreas, which revealed the malignancy of the masses. A pancreaticoduodenectomy and partial gastrectomy were then conducted, and subsequent pathological examinations identified an ASC of the pancreas and a GIST of the stomach. In our case, contrary to the majority of previous cases of synchronous GISTs and other malignancies, GIST was not an incidental finding. The initial suspicion on the GIST as the underlying cause of clinical symptoms led to the discovery of the ASC of the uncinate process of the pancreas.
authors.affiliation: Department of Surgical Oncology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009,  P.R. China ;
authors.forename: Jin-Jie
authors.initials: JJ
authors.lastname: He
authors.forename: Ke-Feng
authors.initials: KF
authors.lastname: Ding
authors.forename: Lei
authors.initials: L
authors.lastname: Zheng
authors.forename: Jing-Hong
authors.initials: JH
authors.lastname: Xu
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.forename: Yu-Lian
authors.initials: YL
authors.lastname: Wu
authors.forename: Li-Feng
authors.initials: LF
authors.lastname: Sun
authors.forename: Dong-Er
authors.initials: DE
authors.lastname: Zhou
authors.forename: Shu
authors.initials: S
authors.lastname: Zheng