title: Perfusing chemotherapy by percutaneous lung puncture in the treatment of extensive drug resistant pulmonary tuberculosis.
abstract: Although progress has been made to reduce global incidence of drug-susceptible tuberculosis, the emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) during the past decade threatens to undermine these advances. XDR-TB has been found to be associated with scarce therapeutic options and high mortality rates. We describe the first case of XDR-TB cured by percutaneous lung puncture and with post-hospital 4 years follow-up involving radiologic imaging and septum smear and TB culture. We also review the epidemiology, diagnosis and treatment of tuberculosis all the world.
authors.affiliation: Department of Tuberculosis, Institute of Tuberculosis Research, Nanjing Chest Hospital, 215 Guangzhou Road, Nanjing 210029, China;
authors.forename: Shu-Hua
authors.initials: SH
authors.lastname: Yang
authors.forename: Ping
authors.initials: P
authors.lastname: Zhan
authors.forename: Mei
authors.initials: M
authors.lastname: Sun
authors.forename: Ya-Ping
authors.initials: YP
authors.lastname: Zhang
authors.forename: Nan-Lan
authors.initials: NL
authors.lastname: Ma