title: Plastic surgical treatment of purpura fulminans: Long-term follow-up of two patients.
abstract: Purpura fulminans (PF) is a rapidly progressing, potentially life-threatening condition characterised by disseminated intravascular coagulation (DIC) and haemorrhagic infarction of the skin. Plastic surgical treatment of PF has never been reported in Scandinavia. The aim of this report was to review plastic surgical treatment of PF and the long-term results of two patients treated in our department. Both patients presented to a community hospital with skin lesions looking like simple traumatic skin bleeds a period after a Varicella infection. They were initially treated at the community hospitals with broad-spectrum antibiotics and adjunctive therapies. When their condition permitted, they were transferred to the department of paediatrics of Skåne University Hospital where their DIC was treated further. The patients were transferred to the department of plastic and reconstructive surgery, when medically stable, and operated on with debridement, and amputation of a toe in one patient, and the application of autologous skin grafts. The children made an excellent recovery and were discharged home after 1.5 months and 3 weeks, respectively. At follow-up, 14 years and 8 years later, respectively, the patients were fully recovered and no secondary corrections were indicated. In conclusion, debridement of necrotic tissue should be performed in a department of plastic and reconstructive surgery as soon as the child is clinically stable, and skin grafting when the wound bed permits it. Follow-up should be performed in the same fashion as for full-thickness burns.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Skåne University Hospital, Malmö, Sweden. emma.hansson@med.lu.se
authors.forename: Emma
authors.initials: E
authors.lastname: Hansson
authors.forename: Ulf
authors.initials: U
authors.lastname: Tedgård
authors.forename: Magnus
authors.initials: M
authors.lastname: Becker
mesh_terms: D002675:Child, Preschool; D003646:Debridement; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D006801:Humans; D007902:Length of Stay; D008297:Male; D008589:Meningococcal Infections; D055665:Purpura Fulminans / Q000150:complications / Q000601:surgery*; D019651:Plastic Surgery Procedures; D016038:Skin Transplantation / Q000379:methods*; D016896:Treatment Outcome