title: Emergence and dissemination of antibiotic resistance: a global problem.
abstract: Antibiotic resistance is a major problem in clinical health settings. Interestingly the origin of many of antibiotic resistance mechanisms can be traced back to non-pathogenic environmental organisms. Important factors leading to the emergence and spread of antibiotic resistance include absence of regulation in the use of antibiotics, improper waste disposal and associated transmission of antibiotic resistance genes in the community through commensals. In this review, we discussed the impact of globalisation on the transmission of antibiotic resistance genes in bacteria through immigration and export/import of foodstuff. The significance of surveillance to define appropriate use of antibiotics in the clinic has been included as an important preventive measure.
authors.affiliation: Infectious Disease Biology, Institute of Life Sciences, Nalco Square, Bhubaneswar-751 023, Odisha, India.
authors.forename: R
authors.initials: R
authors.lastname: Choudhury
authors.forename: S
authors.initials: S
authors.lastname: Panda
authors.forename: D V
authors.initials: DV
authors.lastname: Singh
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D004641:Emigration and Immigration; D022761:Gene Transfer, Horizontal; D006801:Humans; D014195:Travel
chemical_list: D000900:Anti-Bacterial Agents