title: Artery buckling: new phenotypes, models, and applications.
abstract: Arteries are under significant mechanical loads from blood pressure, flow, tissue tethering, and body movement. It is critical that arteries remain patent and stable under these loads. This review summarizes the common forms of buckling that occur in blood vessels including cross-sectional collapse, longitudinal twist buckling, and bent buckling. The phenomena, model analyses, experimental measurements, effects on blood flow, and clinical relevance are discussed. It is concluded that mechanical buckling is an important issue for vasculature, in addition to wall stiffness and strength, and requires further studies to address the challenges. Studies of vessel buckling not only enrich vascular biomechanics but also have important clinical applications.
authors.affiliation: Department of Mechanical Engineering, The University of Texas at San Antonio-UTSA, San Antonio, TX 78249, USA. hchan@utsa.edu
authors.forename: Hai-Chao
authors.initials: HC
authors.lastname: Han
authors.forename: Jennifer K W
authors.initials: JK
authors.lastname: Chesnutt
authors.forename: Justin R
authors.initials: JR
authors.lastname: Garcia
authors.forename: Qin
authors.initials: Q
authors.lastname: Liu
authors.forename: Qi
authors.initials: Q
authors.lastname: Wen
mesh_terms: D000818:Animals; D001158:Arteries / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D010641:Phenotype; D013314:Stress, Mechanical; D014680:Veins / Q000473:pathology / Q000503:physiopathology*