title: Ocular surface neoplasias and human immunodeficiency virus infection.
abstract: OBJECTIVE
  Ocular surface malignancy is a serious complication in HIV infection, but can often result in successful treatment if diagnosed appropriately. In the literature, most reviews focus on information for the ophthalmic community. Here, we provide a review of the literature with the pertinent information for the nonophthalmologist, as they are the first point of contact for most HIV patients.
  
  
  RESULTS
  Ocular surface squamous neoplasia (OSSN) is the most common nonpigmented ocular surface malignancy. It can be treated well with surgery or topical chemotherapy, the newest method of treatment. When presenting in young patients, a high percentage have been found to be HIV positive. Kaposi's sarcoma is an AIDS-defining malignancy and critical to diagnose. It cannot be cured, but treatment is effective for keeping it controlled. Conjunctival lymphoma can be recognized with the salmon patch appearance. External beam radiation, systemic chemotherapy, and intralesional injections are the mainstays of treatment.
  
  
  CONCLUSIONS
  Ocular surface malignancy manifests significantly in the HIV population. OSSN, Kaposi's sarcoma and conjuctival lymphoma all have different clinical presentations. The capacity of the managing physician to recognize these tumours and refer to an ophthalmologist is essential for appropriate treatment.
authors.affiliation: Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.
authors.forename: Jessica E
authors.initials: JE
authors.lastname: Weinstein
authors.forename: Carol L
authors.initials: CL
authors.lastname: Karp
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D003230:Conjunctival Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D011320:Primary Health Care; D012017:Referral and Consultation; D012307:Risk Factors; D012514:Sarcoma, Kaposi / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents