title: Oxidative stress in malaria.
abstract: Malaria is a significant public health problem in more than 100 countries and causes an estimated 200 million new infections every year. Despite the significant effort to eradicate this dangerous disease, lack of complete knowledge of its physiopathology compromises the success in this enterprise. In this paper we review oxidative stress mechanisms involved in the disease and discuss the potential benefits of antioxidant supplementation as an adjuvant antimalarial strategy.
authors.affiliation: Oxidative Stress Research Laboratory, Institute of Biological Sciences, Federal University of Para (LAPEO/ICB/UFPA) Av. Augusto Correa, 1, Guama, Belem, Para 66075-110, Brazil. percario@ufpa.br.
authors.forename: Sandro
authors.initials: S
authors.lastname: Percário
authors.forename: Danilo R
authors.initials: DR
authors.lastname: Moreira
authors.forename: Bruno A Q
authors.initials: BA
authors.lastname: Gomes
authors.forename: Michelli E S
authors.initials: ME
authors.lastname: Ferreira
authors.forename: Ana Carolina M
authors.initials: AC
authors.lastname: Gonçalves
authors.forename: Paula S O C
authors.initials: PS
authors.lastname: Laurindo
authors.forename: Thyago C
authors.initials: TC
authors.lastname: Vilhena
authors.forename: Maria F
authors.initials: MF
authors.lastname: Dolabela
authors.forename: Michael D
authors.initials: MD
authors.lastname: Green
mesh_terms: D000818:Animals; D006461:Hemolysis / Q000276:immunology; D006790:Host-Parasite Interactions; D006801:Humans; D007113:Immunity, Innate / Q000502:physiology; D008288:Malaria / Q000276:immunology* / Q000378:metabolism*; D009569:Nitric Oxide / Q000378:metabolism; D018384:Oxidative Stress / Q000502:physiology*; D010963:Plasmodium falciparum / Q000276:immunology; D017382:Reactive Oxygen Species / Q000378:metabolism
chemical_list: D017382:Reactive Oxygen Species; D009569:Nitric Oxide