title: Evaluation of the histopathological diagnosis of patients preoperatively diagnosed with atypical endometrial hyperplasia after hysterectomy.
abstract: OBJECTIVE
  To evaluate the patients diagnosed with atypical endometrial hyperplasia preoperatively, and compare preoperative and postoperative results.
  
  
  METHODS
  We investigated the files of 58 patients diagnosed with atypical endometrial hyperplasia who were treated surgically after clinical evaluation. We compared sociodemographic diagnosis, preoperative and postoperative diagnosis.
  
  
  RESULTS
  Mean-age of patients was 51.7. Obesity, diabetes mellitus, hypertension and infertility were seen, respectively, in eight cases (13.7%), 12 cases (20.6%), 19 cases (32.7%) and four cases (6.8%). While endometrial cancer was not found postoperatively in patients preoperatively diagnosed with simple atypical endometrial hyperplasia, we determined well differentiated endometrial adenocarcinoma in 44.7% of the patients.
  
  
  CONCLUSIONS
  In the literature the probability of developing well differentiated endometrial cancer from complex atypical endometrial hyperplasia is 40-50%. All patients diagnosed with complex atypical hyperplasia should be evaluated preoperatively for well differentiated adenocarcinoma and undergo an appropriate surgical technique and staging.
authors.affiliation: Izmir Aegean Maternity and Women's Health Hospital, Izmir, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Kurt
authors.forename: O
authors.initials: O
authors.lastname: Demirtaş
authors.forename: A
authors.initials: A
authors.lastname: Kopuz
authors.forename: E
authors.initials: E
authors.lastname: Beyan
authors.forename: G
authors.initials: G
authors.lastname: Demirtaş
authors.forename: A
authors.initials: A
authors.lastname: Besler
authors.forename: O
authors.initials: O
authors.lastname: Altinboğa
mesh_terms: D000368:Aged; D004714:Endometrial Hyperplasia / Q000150:complications / Q000473:pathology* / Q000601:surgery; D016889:Endometrial Neoplasms / Q000209:etiology; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged