title: A pull-back algorithm to determine the unloaded vascular geometry in anisotropic hyperelastic AAA passive mechanics.
abstract: Biomechanical studies on abdominal aortic aneurysms (AAA) seek to provide for better decision criteria to undergo surgical intervention for AAA repair. More accurate results can be obtained by using appropriate material models for the tissues along with accurate geometric models and more realistic boundary conditions for the lesion. However, patient-specific AAA models are generated from gated medical images in which the artery is under pressure. Therefore, identification of the AAA zero pressure geometry would allow for a more realistic estimate of the aneurysmal wall mechanics. This study proposes a novel iterative algorithm to find the zero pressure geometry of patient-specific AAA models. The methodology allows considering the anisotropic hyperelastic behavior of the aortic wall, its thickness and accounts for the presence of the intraluminal thrombus. Results on 12 patient-specific AAA geometric models indicate that the procedure is computational tractable and efficient, and preserves the global volume of the model. In addition, a comparison of the peak wall stress computed with the zero pressure and CT-based geometries during systole indicates that computations using CT-based geometric models underestimate the peak wall stress by 59 ± 64 and 47 ± 64 kPa for the isotropic and anisotropic material models of the arterial wall, respectively.
authors.affiliation: Mechanical Engineering Department/Aragon Institute of Engineering Research, Universidad de Zaragoza, Zaragoza, Spain.
authors.forename: Fabián
authors.initials: F
authors.lastname: Riveros
authors.forename: Santanu
authors.initials: S
authors.lastname: Chandra
authors.forename: Ender A
authors.initials: EA
authors.lastname: Finol
authors.forename: T Christian
authors.initials: TC
authors.lastname: Gasser
authors.forename: Jose F
authors.initials: JF
authors.lastname: Rodriguez
mesh_terms: D000465:Algorithms; D017544:Aortic Aneurysm, Abdominal / Q000473:pathology* / Q000503:physiopathology*; D001696:Biomechanical Phenomena; D001698:Biomedical Engineering; D004548:Elasticity; D020342:Finite Element Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional; D008955:Models, Cardiovascular