title: Acute amiodarone syndrome after a single intravenous amiodarone bolus.
abstract: Acute amiodarone toxicity after a single dose of intravenous amiodarone is very rarely seen. We report the case of a 64-year-old Chinese man who presented with atrial fibrillation and fluid overload due to congestive cardiac failure. He was treated with a single bolus dose of intravenous amiodarone, after which he developed elevated serum transaminases, coagulopathy, thrombocytopenia and acute renal failure. His parameters returned to normal after 25 days and his recovery was uneventful.
authors.affiliation: Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Xin Rong
authors.initials: XR
authors.lastname: Ng
authors.forename: Liang Yi
authors.initials: LY
authors.lastname: Wee
authors.forename: Veerendra
authors.initials: V
authors.lastname: Chadachan
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced; D000638:Amiodarone / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D001281:Atrial Fibrillation / Q000188:drug therapy*; D001778:Blood Coagulation Disorders / Q000139:chemically induced; D006333:Heart Failure / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013921:Thrombocytopenia / Q000139:chemically induced; D000637:Transaminases / Q000097:blood; D016896:Treatment Outcome
chemical_list: D000889:Anti-Arrhythmia Agents; D000637:Transaminases; D000638:Amiodarone