title: Digenic inheritance and Mendelian disease.
abstract: Powerful genomic technologies, such as exome sequencing, are providing new insights into the genetics underlying Mendelian traits. A new study identifies a role for digenic inheritance and an epigenetic modifier in facioscapulohumeral muscular dystrophy type 2.
authors.affiliation: Department of Molecular and Human Genetics and the Department of Pediatrics at the Baylor College of Medicine, Houston, Texas, USA. jlupski@bcm.edu
authors.forename: James R
authors.initials: JR
authors.lastname: Lupski
mesh_terms: D044127:Epigenesis, Genetic; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D006801:Humans; D020391:Muscular Dystrophy, Facioscapulohumeral / Q000235:genetics*