title: Comparison of 320-row computed tomography coronary angiography with conventional angiography for the assessment of coronary artery disease with different atherosclerotic plaque characteristics.
abstract: OBJECTIVE
  The objective of this study was to compare the accuracy of 320-row computed tomography angiography (CTA) with conventional coronary angiography.
  
  
  METHODS
  Two hundred seventy-four patients with coronary artery disease who received both invasive coronary angiography and 320-row CTA were included. Stenosis of 50% or greater was considered obstructive.
  
  
  RESULTS
  In patient-based analysis, accuracy of CTA was 89.4%, with sensitivity of 94.6% and specificity of 54.3%. In segment-based analysis, the overall (4110 segments) accuracy of CTA was 90.7%, with sensitivity of 66.5% and specificity of 95.8%. For the segments with plaques (1191 segments), accuracy of CTA was 80.1%, with sensitivity of 83.5% and specificity of 77.0%. For segments with no plaque (2919 segments), accuracy of CTA was 95.0%, with sensitivity of 0.7% and specificity of 100.0%. For the segments with stents (110 segments), the accuracy of CTA was 86.4%.
  
  
  CONCLUSIONS
  A 320-row CTA has potential to detect coronary lesions with soft and intermediate plaques.
authors.affiliation: Department of Cardiology, The Fourth Affiliated Hospital of Harbin Medical University, Heilongjiang, China.
authors.forename: Qing-Hui
authors.initials: QH
authors.lastname: Yang
authors.forename: Yan-Jun
authors.initials: YJ
authors.lastname: Chen
authors.forename: Qian-Qian
authors.initials: QQ
authors.lastname: Liu
authors.forename: Min
authors.initials: M
authors.lastname: Dong
authors.forename: Liang
authors.initials: L
authors.lastname: Wen
authors.forename: Xiang
authors.initials: X
authors.lastname: Song
authors.forename: Yan-Jie
authors.initials: YJ
authors.lastname: Lv
authors.forename: Ying-Zi
authors.initials: YZ
authors.lastname: Gong
authors.forename: Xue-Qi
authors.initials: XQ
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography / Q000379:methods*; D003324:Coronary Artery Disease / Q000150:complications / Q000000981:diagnostic imaging*; D023921:Coronary Stenosis / Q000150:complications / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D058226:Plaque, Atherosclerotic / Q000150:complications / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D015607:Stents; D014057:Tomography, X-Ray Computed / Q000379:methods*