title: Three-component reaction of propargyl amines, sulfonyl azides, and alkynes: one-pot synthesis of tetrasubstituted imidazoles.
abstract: An efficient and straightforward strategy for the synthesis of tetrasubstituted imidazoles from propargyl amines, sulfonyl azides, and terminal alkynes is described. N-sulfonyl ketenimine and aminoallene are believed to be the key intermediates for this two-step one-pot transformation.
authors.affiliation: Department of Chemistry, Zhejiang University , Hangzhou 310027, PR China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Jiang
authors.forename: Ping
authors.initials: P
authors.lastname: Lu
authors.forename: Yanguang
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D007093:Imidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010293:Pargyline / Q000031:analogs & derivatives* / Q000737:chemistry; D011437:Propylamines / Q000737:chemistry*; D013450:Sulfones / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001386:Azides; D007093:Imidazoles; D011437:Propylamines; D013450:Sulfones; C009054:propargylamine; D010293:Pargyline