title: High dose statins in acute myocardial infarction.
abstract: Patients with acute myocardial infection are vulnerable in the early period for death and recurrent coronary events due to an underlying unstable coronary plaque. Stabilizing the vulnerable plaque is a key strategy in treating these high risk patients. Statins in high doses have proved their utility and safety in secondary prevention trials. Early initiations of statins are beneficial by way of their pleiotropic effects in stabilizing the vulnerable plaque and thus reducing coronary events and death.
authors.affiliation: Institute of Cardiovascular Diseases, Madras Medical Mission, Chennai,Tamil Nadu, India.
authors.forename: Thomas
authors.initials: T
authors.lastname: George
authors.forename: Mullasari S
authors.initials: MS
authors.lastname: Ajit
mesh_terms: D004305:Dose-Response Relationship, Drug; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000008:administration & dosage*; D009203:Myocardial Infarction / Q000188:drug therapy*
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors