title: Synthesis and antibacterial activity of conjugates between norfloxacin and analogues of the siderophore vanchrobactin.
abstract: From synthetic functionalized analogues of vanchrobactin, a siderophore produced by the fish pathogenic bacteria Vibrio anguillarum serotype O2, several vanchrobactin analogues-norfloxacin conjugates were obtained and their antimicrobial activities against the wild-type and mutant strains of Vibrio anguillarum serotype O2 have been determined.
authors.affiliation: Departamento de Química Fundamental, Facultade de Ciencias, Universidade de A Coruña, Campus da Zapateira, A Coruña 15071, Spain.
authors.forename: Alba
authors.initials: A
authors.lastname: Souto
authors.forename: Marcos A
authors.initials: MA
authors.lastname: Montaos
authors.forename: Miguel
authors.initials: M
authors.lastname: Balado
authors.forename: Carlos R
authors.initials: CR
authors.lastname: Osorio
authors.forename: Jaime
authors.initials: J
authors.lastname: Rodríguez
authors.forename: Manuel L
authors.initials: ML
authors.lastname: Lemos
authors.forename: Carlos
authors.initials: C
authors.lastname: Jiménez
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D005393:Fish Diseases / Q000188:drug therapy / Q000382:microbiology*; D009154:Mutation; D009643:Norfloxacin / Q000031:analogs & derivatives* / Q000494:pharmacology; D010455:Peptides / Q000737:chemistry* / Q000494:pharmacology; D017262:Siderophores / Q000737:chemistry* / Q000494:pharmacology; D014733:Vibrio / Q000187:drug effects* / Q000235:genetics; D014735:Vibrio Infections / Q000188:drug therapy / Q000662:veterinary
chemical_list: D000900:Anti-Bacterial Agents; D010455:Peptides; D017262:Siderophores; C529766:vanchrobactin; D009643:Norfloxacin