title: Characterization of a severe hypofibrinogenemia induced by alteplase in two patients thrombolysed for stroke.
authors.forename: Aurélie
authors.initials: A
authors.lastname: Matrat
authors.forename: Philippe
authors.initials: P
authors.lastname: De Mazancourt
authors.forename: Laurent
authors.initials: L
authors.lastname: Derex
authors.forename: Norbert
authors.initials: N
authors.lastname: Nighoghossian
authors.forename: Patrick
authors.initials: P
authors.lastname: Ffrench
authors.forename: Robert
authors.initials: R
authors.lastname: Rousson
authors.forename: Michel
authors.initials: M
authors.lastname: Hanss
mesh_terms: D000347:Afibrinogenemia / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis; D000368:Aged; D015415:Biomarkers / Q000097:blood; D015536:Down-Regulation; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism; D005343:Fibrinolytic Agents / Q000009:adverse effects*; D006801:Humans; D020300:Intracranial Hemorrhages / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D010958:Plasminogen / Q000378:metabolism; D012720:Severity of Illness Index; D020521:Stroke / Q000188:drug therapy*; D015912:Thrombolytic Therapy / Q000009:adverse effects*; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000009:adverse effects*; D000979:alpha-2-Antiplasmin / Q000378:metabolism
chemical_list: D015415:Biomarkers; D005338:Fibrin Fibrinogen Degradation Products; D005343:Fibrinolytic Agents; D000979:alpha-2-Antiplasmin; C036309:fibrin fragment D; D010958:Plasminogen; D010959:Tissue Plasminogen Activator