title: Gene regulatory networks in the Arabidopsis root.
abstract: Thanks to the increasing use of high-throughput tools in genetics, genomics, proteomics and metabolomics, a tremendous amount of information has been generated in the recent years. How these genes, transcripts, proteins and metabolites are inter-connected in a spatiotemporal context is one of the most ambitious goals that fundamental biology needs to answer. Owing to high quality data that are available, Arabidopsis thaliana has become an ideal organism for the application of bioinformatics and systems biology studies. The radially symmetrical structure of the Arabidopsis root and the ability to track developmental time in constrained cell files make this organ the perfect model to investigate different types of biological networks at a cell type-specific level. In this review we present the latest findings in this field as well as our perspective on the future of root biological networks.
authors.affiliation: Department of Plant Biology and Genome Center, University of California Davis, Davis, CA, USA.
authors.forename: Miguel
authors.initials: M
authors.lastname: De Lucas
authors.forename: Siobhan M
authors.initials: SM
authors.lastname: Brady
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development; D019295:Computational Biology; D053263:Gene Regulatory Networks / Q000235:genetics*; D008954:Models, Biological; D009928:Organ Specificity; D018517:Plant Roots / Q000235:genetics* / Q000254:growth & development; D049490:Systems Biology