title: Improved β-carotene production by oxidative stress in Blakeslea trispora induced by liquid paraffin.
abstract: When 3 % (v/v) liquid paraffin was added to the medium, β-carotene production increased from 397 to 715 mg l(-1) in mated cultures of Blakeslea trispora. Liquid paraffin also enhanced the oxygen concentration and induce high oxidative stress, as observed by the increase in activities of superoxide dismutase (SOD), catalase (CAT) and peroxidase (POD). After 84 h of cultivation in the presence of liquid paraffin, the activities of SOD, CAT and POD in B. trispora increased 77, 52.5 and 76.6 %, respectively.
authors.affiliation: State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, P.O. Box 75, Beijing 100029, People's Republic of China. xianmeihu@126.com
authors.forename: Xianmei
authors.initials: X
authors.lastname: Hu
authors.forename: Xiaojing
authors.initials: X
authors.lastname: Ma
authors.forename: Pingwah
authors.initials: P
authors.lastname: Tang
authors.forename: Qipeng
authors.initials: Q
authors.lastname: Yuan
mesh_terms: D002374:Catalase / Q000378:metabolism; D003470:Culture Media / Q000737:chemistry; D008899:Mineral Oil / Q000633:toxicity*; D009090:Mucorales / Q000187:drug effects*; D018384:Oxidative Stress; D010100:Oxygen / Q000633:toxicity; D009195:Peroxidase / Q000378:metabolism; D013482:Superoxide Dismutase / Q000378:metabolism; D019207:beta Carotene / Q000096:biosynthesis*
chemical_list: D003470:Culture Media; D019207:beta Carotene; D008899:Mineral Oil; D002374:Catalase; D009195:Peroxidase; D013482:Superoxide Dismutase; D010100:Oxygen