title: Epididymal mitochondrial status of hypothyroid rats examined by transmission electron microscopy.
abstract: Hypothyroid rats show alterations in the mobility of sperm recovered from their epididymides. The AgNOR technique, immunohistochemistry and transmission electron microscopy were used to investigate changes in epithelial cells from epididymides of rats treated with (131)I. Counting of NORs did not permit detection of changes in the proliferative capacity of epididymides of hypothyroid animals. Transmission electron microscopy revealed changes in the mitochondria of hypothyroid rats that probably are associated with incipient apoptosis.
authors.affiliation: Clinical Biochemistry Department, Clinical Hospital, Buenos Aires University, Buenos Aires, Argentina. luispalaoro@yahoo.com.ar
authors.forename: L A
authors.initials: LA
authors.lastname: Palaoro
authors.forename: A E
authors.initials: AE
authors.lastname: Rocher
authors.forename: O E
authors.initials: OE
authors.lastname: Canessa
authors.forename: S
authors.initials: S
authors.lastname: Peressini
authors.forename: M
authors.initials: M
authors.lastname: Rosales
authors.forename: A G
authors.initials: AG
authors.lastname: Del Río
authors.forename: G
authors.initials: G
authors.lastname: Mendeluk
mesh_terms: D000199:Actins / Q000378:metabolism; D000818:Animals; D034961:Antigens, Nuclear / Q000378:metabolism; D017209:Apoptosis; D004195:Disease Models, Animal; D004822:Epididymis / Q000378:metabolism / Q000648:ultrastructure*; D004847:Epithelial Cells / Q000378:metabolism / Q000648:ultrastructure; D007037:Hypothyroidism / Q000378:metabolism / Q000473:pathology*; D007150:Immunohistochemistry; D008297:Male; D046529:Microscopy, Electron, Transmission; D008928:Mitochondria / Q000378:metabolism / Q000648:ultrastructure*; D051381:Rats; D017208:Rats, Wistar; D011988:Receptors, Thyroid Hormone / Q000378:metabolism
chemical_list: D000199:Actins; D034961:Antigens, Nuclear; D011988:Receptors, Thyroid Hormone; C051963:nucleolar organizer region associated proteins