title: Diffusion-weighted imaging: As the first diagnostic clue to Creutzfeldt Jacob disease.
abstract: We describe a case report where the diagnosis of sporadic Creutzfeldt-Jakob disease(CJD) was suspected by the magnetic resonance imaging (MRI) radiologist in a 75-year-old lady who presented with rapid cognitive decline. MRI revealed cortical T2 and FLAIR(fluid attenuation and inversion recovery) hyperintensities in bilateral fronto-parietal and temporo-occipital locations and showed significant restriction on diffusion-weighted images(DWI). In this case report, we discuss the role of MRI to suspect the diagnosis of CJD in appropriate clinical settings.
authors.affiliation: Department of Radiology, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, Karnataka, India.
authors.forename: Sunitha P
authors.initials: SP
authors.lastname: Kumaran
authors.forename: Kanchan
authors.initials: K
authors.lastname: Gupta
authors.forename: Bt
authors.initials: B
authors.lastname: Pushpa
authors.forename: Sanjaya
authors.initials: S
authors.lastname: Viswamitra
authors.forename: Ev
authors.initials: E
authors.lastname: Joshy