title: [Endogenous cannabinoid system and depression].
abstract: Endogenous cannabinoid system (ECS) is highly conserved during evolution of the body's endocrine network. It is a regulator of mood, cognitive, autonomic nervous system and movement control system. ECS dysfunction can promote the progress and maintain of depression, phobia, and extreme anxiety. The antidepressant drugs to enhance the activity of ECS may represent a new direction, but rarely reported research in this regard.
authors.affiliation: Department of Functional Experimental Science, Yanji 133000, China.
authors.forename: Hai-Ling
authors.initials: HL
authors.lastname: Yu
authors.forename: Feng
authors.initials: F
authors.lastname: Zhang
authors.forename: Zhe-Shan
authors.initials: ZS
authors.lastname: Quan
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology; D063385:Cannabinoid Receptor Modulators / Q000378:metabolism; D003863:Depression / Q000378:metabolism / Q000503:physiopathology*; D063388:Endocannabinoids / Q000502:physiology*; D006801:Humans; D043882:Receptors, Cannabinoid / Q000378:metabolism*
chemical_list: D000928:Antidepressive Agents; D063385:Cannabinoid Receptor Modulators; D063388:Endocannabinoids; D043882:Receptors, Cannabinoid