title: Prevalence of transmitted HIV-1 drug resistance mutations in children and adolescents in São Paulo, Brazil.
abstract: HIV drug resistance genotype testing, performed on 39 HIV-infected treatment-naive children from 2000 to 2011, identified 5 children (12.8%) with drug resistance mutations: 5.3% to nucleoside reverse transcriptase inhibitors, 5.3% to nonnucleoside reverse transcriptase inhibitors and 7.7% to protease inhibitors. There was a trend for increasing prevalence of drug resistance mutations during the 11-year study period.
authors.affiliation: Division of Pediatric Infectious Diseases, Santa Casa de São Paulo Hospital, Adolfo Lutz Institute, São Paulo, Brazil. flaviaja@gmail.com
authors.forename: Flávia Jacqueline
authors.initials: FJ
authors.lastname: Almeida
authors.forename: Rosangela
authors.initials: R
authors.lastname: Rodrigues
authors.forename: Mayra Simioni
authors.initials: MS
authors.lastname: Zaparoli
authors.forename: Eitan Naaman
authors.initials: EN
authors.lastname: Berezin
authors.forename: Marco Aurélio Palazzi
authors.initials: MA
authors.lastname: Sáfadi
authors.forename: João Leandro
authors.initials: JL
authors.lastname: de Paula Ferreira
authors.forename: André Minhoto
authors.initials: AM
authors.lastname: Lança
authors.forename: Luis Fernando
authors.initials: LF
authors.lastname: de Macedo Brígido
mesh_terms: D000293:Adolescent; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D024882:Drug Resistance, Viral; D005260:Female; D005838:Genotype; D015658:HIV Infections / Q000453:epidemiology / Q000635:transmission* / Q000821:virology*; D015497:HIV-1 / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D020125:Mutation, Missense; D015995:Prevalence