title: Hormonal contraceptive continuation and switching in South Africa: implications for evaluating the association of injectable hormonal contraceptive use and HIV.
abstract: Investigating the association between hormonal contraception and HIV is challenging due to high discontinuation rates among users. This secondary analysis of 262 South African adolescent new users of hormonal contraception found continuation rates after 1 year for depot medroxyprogesterone acetate, norethisterone enanthate, or combined oral contraceptives of 40.4%, 64.4%, and 64.6%, respectively. Implications for studies evaluating the association between injectable hormonal contraceptive use and HIV are discussed.
authors.affiliation: MatCH, Maternal, Adolescent, and Child Health, Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, South Africa. jsmit@match.org.za
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Smit
authors.forename: Mags E
authors.initials: ME
authors.lastname: Beksinska
mesh_terms: D000293:Adolescent; D015331:Cohort Studies; D003268:Contraception Behavior / Q000706:statistics & numerical data*; D003271:Contraceptive Agents, Female / Q000008:administration & dosage*; D003278:Contraceptives, Oral, Hormonal / Q000008:administration & dosage; D057915:Drug Substitution / Q000706:statistics & numerical data*; D005260:Female; D015658:HIV Infections / Q000517:prevention & control*; D006801:Humans; D007267:Injections; D013019:South Africa; D055815:Young Adult
chemical_list: D003271:Contraceptive Agents, Female; D003278:Contraceptives, Oral, Hormonal