title: Pneumophonic coordination impairments in parkinsonian dysarthria: importance of aerodynamic parameters measurements.
abstract: BACKGROUND
  Among Parkinsonian axial signs, dysarthria represents an important disabling symptom able to lead towards a significant reduction of oral communication. Several methods of dysarthria assessment have been used but aerodynamic evaluation is rare in the literature.
  
  
  OBJECTIVE
  To highlight the importance of aerodynamic parameters measurements in assessment of parkinsonian dysarthria.
  
  
  METHODS
  Using a dedicated system (EVA2), 24 parkinsonian patients were recorded after withdrawal of L-dopa for at least 12 h (condition called OFF DOPA) in order to evaluate intra-oral pressure (IOP), mean oral air flow (MOAF) and laryngeal resistance (LR) on six /p/ during realization of the sentence "Papa ne m'a pas parle' de beau-papa" ("Daddy did not speak to me about daddy-in-law") which corresponds to a breath group. 50 control subjects were recorded in parallel in order to define reference measurements.
  
  
  RESULTS
  It appeared that there is in Parkinson's disease aerodynamic impairments which were evidenced by the fall in IOP and that of MOAF in patients compared with control subjects. The difference between the two groups was statistically significant. In addition a greater instability of LR in patients compared with control subjects was also noted.
  
  
  CONCLUSIONS
  Our results show that measurements of aerodynamics parameters, by reflecting the dysfunction induced by disease, may well be relevant factors in parkinsonian dysarthria evaluation.
authors.affiliation: UFR Santé Ex 10éme RAIO M - Université de Thiès BP 967 Thiès - Sénégal.
authors.forename: S M
authors.initials: SM
authors.lastname: Moustapha
authors.forename: G
authors.initials: G
authors.lastname: Alain
authors.forename: E
authors.initials: E
authors.lastname: Robert
authors.forename: T
authors.initials: T
authors.lastname: Bernard
authors.forename: Kâ M
authors.initials: KM
authors.lastname: Mourtalla
authors.forename: G
authors.initials: G
authors.lastname: Lamine
authors.forename: V
authors.initials: V
authors.lastname: François
mesh_terms: D000978:Antiparkinson Agents / Q000627:therapeutic use; D001259:Ataxia / Q000175:diagnosis* / Q000209:etiology; D003936:Diagnosis, Computer-Assisted / Q000379:methods; D004185:Disability Evaluation; D004401:Dysarthria / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D013061:Speech Acoustics; D013068:Speech Production Measurement / Q000379:methods; D063189:Symptom Assessment
chemical_list: D000978:Antiparkinson Agents