title: [Why should antibiotic therapy be avoided in case of acute infectious diarrhea?].
abstract: Antibiotic prescription for acute diarrhea is not devoid of risks. There are individual risks for the patient, such as allergy, gastrointestinal side effects, Clostridium difficile infection. There is also a risk of selection of antibiotic resistance in the digestive microbiota, leading to the emergence of multiresistant isolates such as extended-spectrum β-lactamase or carbapenemase producing Enterobacteriaceae, which are able to disseminate worldwide. Antibiotic prescriptions may thus be limited to patients with entero-invasive or severe choleriform diarrhea.
authors.affiliation: AP-HP, université Paris-Diderot, faculté Bichat, hôpital Beaujon, service de médecine interne, EA3964, 75870 Paris cedex 18, France. agnes.lefort@bjn.aphp.fr
authors.forename: Agnès
authors.initials: A
authors.lastname: Lefort
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use; D000075202:Contraindications; D003967:Diarrhea / Q000209:etiology / Q000628:therapy*; D004352:Drug Resistance, Microbial / Q000502:physiology; D004403:Dysentery / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy; D004756:Enterobacteriaceae Infections / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007239:Infections / Q000150:complications / Q000628:therapy*
chemical_list: D000900:Anti-Bacterial Agents