title: Pachydermodactyly: Three new cases in Taiwan.
abstract: Pachydermodactyly (PDD), Greek for thick-skin-finger, is an infrequently recognized benign disorder characterized by painless fusiform swelling of the soft tissues around the proximal interphalangeal joints of the hands. Histopathologic features include increased dermal accumulation of collagen fibers. Young males are predominantly affected. PDD is quite rare with approximately 90 cumulative cases reported worldwide. We report three new cases of PDD in Taiwan, including two female patients. Except for patient 1 having the habit of cracking the knuckles, and patient 2 having a history of patent ductus ateriosus post catheterization, the histories of all three patients were unremarkable. X-ray of bilateral hands revealed no abnormal finding except for soft tissue swelling around proximal interphalangeal joints. Laboratory examinations all showed negative results. No local or systemic treatment was given to these patients to treat PDD, with the exception of non-steroidal anti-inflammatory drugs prescribed to one patient for a short period. Skin care with local irritation avoidance was explained to all three patients. The long-term outcome of PDD was benign.
authors.affiliation: Department of Pediatrics, Taiwan Adventist Hospital, Taipei, Taiwan; Division of Allergy, Immunology, Rheumatology Disease, Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Chen-Kuan
authors.initials: CK
authors.lastname: Chen
authors.affiliation: Division of Allergy, Immunology, Rheumatology Disease, Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan. Electronic address: abc4540@gmail.com.
authors.forename: Shyh-Dar
authors.initials: SD
authors.lastname: Shyur
authors.affiliation: Division of Allergy, Immunology, Rheumatology Disease, Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Szu-Hung
authors.initials: SH
authors.lastname: Chu
authors.affiliation: Division of Allergy, Immunology, Rheumatology Disease, Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Li-Hsin
authors.initials: LH
authors.lastname: Huang
authors.affiliation: Division of Allergy, Immunology, Rheumatology Disease, Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Yu-Hsuan
authors.initials: YH
authors.lastname: Kao
authors.affiliation: Division of Allergy, Immunology, Rheumatology Disease, Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan.
authors.forename: Ling-Chun
authors.initials: LC
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D005350:Fibroma / Q000151:congenital* / Q000175:diagnosis / Q000473:pathology; D005385:Fingers / Q000002:abnormalities* / Q000473:pathology*; D006801:Humans; D008297:Male; D012867:Skin / Q000473:pathology*; D013624:Taiwan