title: Surgical treatment of inspissated bile syndrome using a 2-stage pure laparoscopic approach: a case report.
abstract: We describe a 99-day old girl with inspissated bile syndrome (IBS) unresponsive to treatment with oral ursodeoxycholic acid. We performed a pure laparoscopic 2-stage procedure, consisting of cholecystostomy and insertion of an indwelling balloon catheter for local ursodeoxycholic acid flushing for 13 consecutive days. Subsequently, the cholecystostomy was removed, preserving the gallbladder using the same laparoscopical approach when bilirubin values returned to normal and bile duct obstruction was no longer detectable radiologically. This is the first report of an exclusively laparoscopic management of IBS.
authors.affiliation: University Children's Hospital, Department of Pediatric Surgery and Pediatric Urology, Hoppe-Seyler-Strasse 1, D-72076 Tuebingen, Germany. justus.lieber@med.uni-tuebingen.de
authors.forename: Justus
authors.initials: J
authors.lastname: Lieber
authors.forename: Femke E
authors.initials: FE
authors.lastname: Piersma
authors.forename: Ekkehard
authors.initials: E
authors.lastname: Sturm
authors.forename: Jürgen F
authors.initials: JF
authors.lastname: Schäfer
authors.forename: Jörg
authors.initials: J
authors.lastname: Fuchs
authors.forename: Philipp O
authors.initials: PO
authors.lastname: Szavay
mesh_terms: D002758:Cholangiography / Q000379:methods; D017081:Cholecystectomy, Laparoscopic / Q000379:methods*; D002767:Cholecystostomy / Q000379:methods*; D001651:Cholestasis, Extrahepatic / Q000000981:diagnostic imaging / Q000601:surgery*; D003131:Combined Modality Therapy / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D018570:Risk Assessment; D013577:Syndrome; D007507:Therapeutic Irrigation / Q000379:methods; D016896:Treatment Outcome; D014580:Ursodeoxycholic Acid / Q000378:metabolism*
chemical_list: D014580:Ursodeoxycholic Acid