title: A one-pot approach to Δ2-isoxazolines from ketones and arylacetylenes.
abstract: The sequential reaction of ketones with arylacetylenes and hydroxylamine in the presence of KOBu(t)/DMSO followed by the treatment of the reaction mixture with H(2)O and KOH leads to Δ(2)-isoxazolines in up to 88% yield.
authors.affiliation: A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, 1 Favorsky Str., 664033 Irkutsk, Russia.
authors.forename: Elena Yu
authors.initials: EY
authors.lastname: Schmidt
authors.forename: Inna V
authors.initials: IV
authors.lastname: Tatarinova
authors.forename: Elena V
authors.initials: EV
authors.lastname: Ivanova
authors.forename: Nadezhda V
authors.initials: NV
authors.lastname: Zorina
authors.forename: Igor' A
authors.initials: IA
authors.lastname: Ushakov
authors.forename: Boris A
authors.initials: BA
authors.lastname: Trofimov
mesh_terms: D000114:Acetylene / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D019811:Hydroxylamine / Q000737:chemistry; D007555:Isoxazoles / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D007555:Isoxazoles; D007659:Ketones; D019811:Hydroxylamine; D000114:Acetylene