title: [Production and control of water quality for hemodialysis].
abstract: Certain substances present in drinking water can harm hemodialysis patients if they are not removed before the preparation of the dialysate. An optimal water treatment system includes tap water pretreatment and a double reverse osmosis process. Every component, including the delivery of the treated water to the dialysis machines, contributes to preventing chemical and microbiological contamination. Quality standards for dialysis water do not differ from those for intravenous drug safety and the progress toward the goals depends on practical solutions to important issues, including how the standard is to be applied and whether it should be limited to substances with well-documented toxicity in hemodialysis patients, and how microbiological contaminants should be handled. Meeting the standards for the new dialysis methods and membranes requires protocols for the development of a facility-specific quality management system to ensure dialysate quality based on the validation of system performance coupled with routine monitoring and periodic revalidation.
authors.affiliation: S.C. di Nefrologia e Dialisi, Dipartimento Specialita' Mediche, Azienda Ospedaliera C. Poma, Mantova - Italy.
authors.forename: Renzo
authors.initials: R
authors.lastname: Tarchini
authors.forename: Pierluigi
authors.initials: P
authors.lastname: Botti
authors.forename: Cosimo Damiano
authors.initials: CD
authors.lastname: Marseglia
authors.forename: Paola
authors.initials: P
authors.lastname: Brescia
authors.forename: Alessia
authors.initials: A
authors.lastname: Serra
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Mazzola
authors.forename: Gianni
authors.initials: G
authors.lastname: Rovinetti
mesh_terms: D015314:Dialysis Solutions; D006801:Humans; D006435:Renal Dialysis; D014867:Water / Q000592:standards*; D018508:Water Purification
chemical_list: D015314:Dialysis Solutions; D014867:Water