title: Stereoselective synthesis of 2,6-trans-tetrahydropyrans.
abstract: A stereoselective route to the thermodynamically unfavorable 2,6-trans-tetrahydropyrans has been developed from coupling of hydroxyethyl-tethered cyclopropanols and aliphatic aldehydes. Noteworthy is high convergency from direct coupling of two segments.
authors.affiliation: Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States.
authors.forename: Bibhuti Bhusan
authors.initials: BB
authors.lastname: Parida
authors.forename: Ivan L
authors.initials: IL
authors.lastname: Lysenko
authors.forename: Jin Kun
authors.initials: JK
authors.lastname: Cha
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D003500:Cyclization; D004988:Ethers, Cyclic / Q000737:chemistry*; D015394:Molecular Structure; D011714:Pyrans / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013816:Thermodynamics
chemical_list: D000447:Aldehydes; D004988:Ethers, Cyclic; D011714:Pyrans; C043657:cyclopropanol