title: [Harm reduction centers ("CAARUD"): privileged places for warning signal detection in addictovigilance].
abstract: This study aims to describe profile and consumptions of subjects suffering a         substance use disorder recruited in harm reduction centers (HRC, French "CAARUD", 156         included subjects in 7 centers) for the 2010 OPPIDUM survey, performed by the French         CEIP-Addictovigilance network, in order to compare them to subjects included in ambulatory         care centers (ACC, French "CSAPA", 3549 subjects included in 80 centers).          Subjects         recruited in HRC are younger and more precarious; they consume more illicit drugs, and         prescription drugs known to be diverted (methylphenidate, morphine, ketamine,…). They         consume less opiate maintenance treatment, antidepressants and psychotics. Obtaining and         consumption modalities are also different (more illegal acquisitions for prescription drugs,         more intravenous route use and less nasal route use in HRC).          HRC are privileged places for         watching substance use disorder (abuse, dependence) or prescription drugs diversions, and         for early warning signal detection in addictovigilance.
authors.affiliation: Centre d'Addictovigilance de Marseille, Pharmacologie clinique, Hôpitaux de la Timone, Assistance Publique Hôpitaux de Marseille, Marseille, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Moracchini
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Frauger
authors.forename: Vanessa
authors.initials: V
authors.lastname: Pauly
authors.forename: Sandra
authors.initials: S
authors.lastname: Nordmann
authors.forename: Xavier
authors.initials: X
authors.lastname: Thirion
authors.forename: Joëlle
authors.initials: J
authors.lastname: Micallef
mesh_terms: D000328:Adult; D016739:Behavior, Addictive / Q000145:classification / Q000453:epidemiology / Q000209:etiology; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D060735:Pharmacovigilance; D018571:Sentinel Surveillance; D015813:Substance Abuse Detection / Q000379:methods / Q000706:statistics & numerical data; D016320:Substance Abuse Treatment Centers / Q000706:statistics & numerical data*; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000517:prevention & control; D055815:Young Adult