title: Sodium bicarbonate to prevent cardiac surgery-associated kidney injury: the end of a dream?
abstract: The rationale of urine alkalinization through intravenous sodium bicarbonate to prevent cardiac surgery-associated acute kidney injury relies on several pathophysiological arguments. Urine alkalinization is easily feasible in the ICU setting and is often considered to be associated with few side effects. In a previous issue of Critical Care, a retrospective study evaluates the effect of routine intravenous bicarbonate use to prevent cardiac surgery-associated acute kidney injury with cardiopulmonary bypass. This commentary discusses recent data on the use of bicarbonate to prevent cardiac surgery-associated acute kidney injury.
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Hougardy
authors.forename: Daniel
authors.initials: D
authors.lastname: De Backer
mesh_terms: D058186:Acute Kidney Injury / Q000517:prevention & control*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D017693:Sodium Bicarbonate / Q000008:administration & dosage*
chemical_list: D017693:Sodium Bicarbonate