title: Low-volume whole-body vibration lasting 3 or 6 months does not affect biomarkers in blood serum of rats.
abstract: Whole-body vibration training (WBV) has been reported to improve both, bone strength and neuromuscular performance. Although changes in hormonal and immunological parameters following vibration exercises were reported, there are still few studies concerning the immune response with respect to different duration of WBV. In our study, we aimed to establish whether three and six months of specific, short-lasting WBV (four bouts lasting 30 s, 1 min rest intervals) influences blood cell counts as well as some immunological parameters in rats. Adult male Wistar rats were assigned randomly to two groups trained for three (WBV3mo) or six (WBV6mo) months and results were compared to the age matched control group (C). After the training period, red and white blood cells, lymphocytes, monocytes, granulocytes, hemoglobin, and hematocrit, as well as interleukin-1b, interleukin-10, interleukin-6, and vascular endothelial growth factor levels were determined. No significant differences between WBV3mo, WBV6mo, and C groups in complete blood counts or in immunological parameters were found, indicating that the whole-body vibration training used in this study did not disturb the balance of examined indices, directly or indirectly involved in inflammatory processes.
authors.affiliation: University School of Physical Education in Poznań Department of Biochemistry Poznań Poland University School of Physical Education Department of Biochemistry, Chair of Physiology, Biochemistry and Hygiene Królowej Jadwigi 27/39 61-871 Poznań Poland.
authors.forename: Matthias
authors.initials: M
authors.lastname: Pawlak
authors.forename: D
authors.initials: D
authors.lastname: Kaczmarek
authors.forename: A
authors.initials: A
authors.lastname: Nowak
authors.forename: P
authors.initials: P
authors.lastname: Krutki
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood*; D001773:Blood Cells / Q000378:metabolism; D006400:Hematocrit; D006454:Hemoglobins / Q000378:metabolism; D007378:Interleukins / Q000097:blood; D008297:Male; D010805:Physical Conditioning, Animal / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D042461:Vascular Endothelial Growth Factor A / Q000097:blood; D014732:Vibration
chemical_list: D015415:Biomarkers; D006454:Hemoglobins; D007378:Interleukins; D042461:Vascular Endothelial Growth Factor A