title: Use of i-scan Endoscopic Image Enhancement Technology in Clinical Practice to Assist in Diagnostic and Therapeutic Endoscopy: A Case Series and Review of the Literature.
abstract: Background. i-scan is a software-driven technology that allows modifications of sharpness, hue, and contrast to enhance mucosal imaging. It uses postimage acquisition software with real-time mapping technology embedded in the endoscopic processor. Aims. To review applications of i-scan technology in clinical endoscopic practice. Methods. This is a case series of 20 consecutive patients who underwent endoscopic procedures where i-scan image enhancement algorithms were applied. The main outcome measures were to compare mucosal lesions with high-definition white light endoscopy (HD-WLE) and i-scan image enhancement for the application of diagnostic sampling and therapy. Results. 13 cases involving the upper GI tract and 7 cases of the lower GI tract are included. For upper GI tract pathology i-scan assisted in diagnosis or therapy of Barrett's esophagus with dysplasia, esophageal adenocarcinoma, HSV esophagitis, gastric MALT lymphoma, gastric antral intestinal metaplasia with dysplasia, duodenal follicular lymphoma, and a flat duodenal adenoma. For lower GI tract pathology i-scan assisted in diagnosis or therapy of right-sided serrated adenomas, flat tubular adenoma, rectal adenocarcinoma, anal squamous cell cancer, solitary rectal ulcer, and radiation proctitis. Conclusions. i-scan imaging provides detailed topography of mucosal surfaces and delineates lesion edges, which can directly impact endoscopic management.
authors.affiliation: Division of Gastroenterology and Hepatology, School of Medicine and Public Health, University of Wisconsin, 4th Floor, UWMF Centennial Building, 1685 Highland Avenue, Suite 4000, Madison, WI 53705-2281, USA.
authors.forename: Shawn
authors.initials: S
authors.lastname: Hancock
authors.forename: Erik
authors.initials: E
authors.lastname: Bowman
authors.forename: Jyothiprashanth
authors.initials: J
authors.lastname: Prabakaran
authors.forename: Mark
authors.initials: M
authors.lastname: Benson
authors.forename: Rashmi
authors.initials: R
authors.lastname: Agni
authors.forename: Patrick
authors.initials: P
authors.lastname: Pfau
authors.forename: Mark
authors.initials: M
authors.lastname: Reichelderfer
authors.forename: Jennifer
authors.initials: J
authors.lastname: Weiss
authors.forename: Deepak
authors.initials: D
authors.lastname: Gopal