title: Safety profile assessment and efficacy of chemically characterized Cinnamomum glaucescens essential oil against storage fungi, insect, aflatoxin secretion and as antioxidant.
abstract: The study explores the efficacy of Cinnamomum glaucescens essential oil (EO) as insecticidal, antifungal, antiaflatoxin and antioxidant agent so as to recommend its application as plant based preservatives for food commodities. The study reports the chemical characterization of C. glaucescens oil and its 100% insecticidal activity against insect pest Callosobruchus chinensis on 12 h exposure and 98.74% oviposition deterrency at 0.15 μl/ml. The EO significantly inhibited growth and aflatoxin production by toxigenic strain of Aspergillus flavus LHP-10 at 4.5 and 3.5 μl/ml respectively. EO also showed appreciable antioxidant activity (IC(50) value=15.1 μl/ml), non phytotoxic nature on chickpea seed germination and in vivo potential as fumigant in food system providing 71.07% protection of chickpea samples from fungal contamination and 100% antifeedant activity against the insect invasion. The EO exhibited non-mammalian toxicity showing high LD(50) (3971.34 μl/kg) during oral toxicity on mice.
authors.affiliation: Laboratory of Herbal Pesticides, Centre of Advanced Study in Botany, Banaras Hindu University, Varanasi 221005, UP, India.
authors.forename: Bhanu
authors.initials: B
authors.lastname: Prakash
authors.forename: Priyanka
authors.initials: P
authors.lastname: Singh
authors.forename: Shilpee
authors.initials: S
authors.lastname: Yadav
authors.forename: S C
authors.initials: SC
authors.lastname: Singh
authors.forename: N K
authors.initials: NK
authors.lastname: Dubey
mesh_terms: D000348:Aflatoxins / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D001231:Aspergillus flavus / Q000187:drug effects; D029863:Cicer / Q000187:drug effects / Q000382:microbiology; D027424:Cinnamomum / Q000737:chemistry*; D005260:Female; D005506:Food Contamination / Q000517:prevention & control; D005516:Food Microbiology; D061353:Food Storage; D005658:Fungi / Q000187:drug effects*; D020128:Inhibitory Concentration 50; D007313:Insecta / Q000187:drug effects*; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D009822:Oils, Volatile / Q000494:pharmacology*
chemical_list: D000348:Aflatoxins; D000935:Antifungal Agents; D000975:Antioxidants; D009822:Oils, Volatile