title: Quality metrics for high order meshes: analysis of the mechanical simulation of the heart beat.
abstract: The quality of a computational mesh is an important characteristic for stable and accurate simulations. Quality depends on the regularity of the initial mesh, and in mechanical simulations it evolves in time, with deformations causing changes in volume and distortion of mesh elements. Mesh quality metrics are therefore relevant for both mesh personalization and the monitoring of the simulation process. This work evaluates the significance, in meshes with high order interpolation, of four quality metrics described in the literature, applying them to analyse the stability of the simulation of the heart beat. It also investigates how image registration and mesh warping parameters affect the quality and stability of meshes. Jacobian-based metrics outperformed or matched the results of coarse geometrical metrics of aspect ratio or orthogonality, although they are more expensive computationally. The stability of simulations of a complete heart cycle was best predicted with a specificity of 61%, sensitivity of 85%, and only nominal differences were found changing the intra-element and per-element combination of quality values. A compromise between fitting accuracy and mesh stability and quality was found. Generic geometrical quality metrics have a limited success predicting stability, and an analysis of the simulation problem may be required for an optimal definition of quality.
authors.affiliation: Department of Biomedical Engineering, King's College London, St. Thomas Hospital, London, UK. pablo.lamata@kcl.ac.uk
authors.forename: Pablo
authors.initials: P
authors.lastname: Lamata
authors.forename: Ishani
authors.initials: I
authors.lastname: Roy
authors.forename: Bojan
authors.initials: B
authors.lastname: Blazevic
authors.forename: Andrew
authors.initials: A
authors.lastname: Crozier
authors.forename: Sander
authors.initials: S
authors.lastname: Land
authors.forename: Steven A
authors.initials: SA
authors.lastname: Niederer
authors.forename: D Rod
authors.initials: DR
authors.lastname: Hose
authors.forename: Nicolas P
authors.initials: NP
authors.lastname: Smith
mesh_terms: D000465:Algorithms; D000704:Analysis of Variance; D003198:Computer Simulation; D006321:Heart / Q000033:anatomy & histology* / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging; D008955:Models, Cardiovascular; D012680:Sensitivity and Specificity