title: Lactation Biology Symposium: maternal nutrition during early and mid-to-late pregnancy: Comparative effects on milk production of twin-born ewe progeny during their first lactation.
abstract: Studies using sheep models indicate that the fetal mammary gland is sensitive to maternal nutrition during gestation; however, results have been inconsistent and do not identify critical feeding periods. This study aimed to clarify previous findings by partitioning the period of maternal nutritional manipulation into 2 stages: early and mid-to-late pregnancy. Sixty-six twin-born, twin-bearing ewes, born to dams that were fed either submaintenance, maintenance, or ad libitum during early pregnancy (d 21 to 50 of pregnancy; SmP21-50, MP21-50, or AdP21-50, respectively) and then either maintenance or ad libitum during mid-to-late pregnancy (d 50 to 140 of pregnancy; MP50-140 or AdP50-140, respectively) were milked once a week, starting from d 7 ± 1 postpartum, for 7 subsequent weeks to enable estimation of daily milk yield and composition. Their lambs were weighed weekly. Ewes born to dams fed MP21-50 tended to have greater accumulated milk (P = 0.10), fat (P = 0.07), and NE (P = 0.06) yields over 50 d compared with ewes born to dams fed SmP21-50 and AdP21-50. In contrast, ewes born to dams fed AdP50-140 tended to have greater accumulated milk (P = 0.10) and lactose (P = 0.09) yields compared with ewes born to dams fed MP50-140. Grandoffspring birth weights were unaffected by granddam nutrition during pregnancy. Ewes born to dams fed AdP21-50 weaned lighter lambs (P = 0.05) than ewes born to dams fed AmP21-50 and tended to wean lighter lambs (P = 0.07) than ewes born to dams fed MP21-50 whereas there were no differences between the weaning weights of lambs (P = 0.43) from ewes born to dams fed AdP50-140 and MP50-140. Maintenance nutrition of dams during early pregnancy appears to be associated with an improved lactation performance of ewe offspring. Higher levels of nutrition during mid-to-late pregnancy also appears to improve the first-lactation performance of ewe offspring. Interestingly, although grandoffspring birth weights were unaffected, weaning weight appears to be influenced by granddam early pregnancy nutrition in a manner discordant with the lactational performance of their dam. Results from this study indicate that dam nutrition during early pregnancy can influence the lactational performance of ewe offspring and the BW at weaning of their grandoffspring, which may ultimately affect farmer profits. This highlights the importance of nutritional management of breeding ewes during this period.
authors.affiliation: International Sheep Research and National Research Centre for Growth and Development, Massey University, Palmerston North, New Zealand. a.m.paten@massey.ac.nz
authors.forename: A M
authors.initials: AM
authors.lastname: Paten
authors.forename: P R
authors.initials: PR
authors.lastname: Kenyon
authors.forename: N
authors.initials: N
authors.lastname: Lopez-Villalobos
authors.forename: S W
authors.initials: SW
authors.lastname: Peterson
authors.forename: C M C
authors.initials: CM
authors.lastname: Jenkinson
authors.forename: S J
authors.initials: SJ
authors.lastname: Pain
authors.forename: H T
authors.initials: HT
authors.lastname: Blair
mesh_terms: D000821:Animal Feed / Q000032:analysis; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001835:Body Weight / Q000235:genetics / Q000502:physiology; D004032:Diet / Q000662:veterinary; D005260:Female; D007774:Lactation / Q000502:physiology*; D039382:Maternal Nutritional Physiological Phenomena; D008892:Milk / Q000502:physiology*; D011247:Pregnancy; D011272:Pregnancy, Multiple / Q000502:physiology*; D012756:Sheep / Q000235:genetics / Q000254:growth & development / Q000502:physiology*