title: [Possibilities provided by personalized therapy of chronic hepatitis C (case conference at E.M.Tareev Clinic of Nephrology, Internal and Occupational Diseases)].
abstract: The presented clinical case gave rise to discussion of the main mechanisms and factors behind the progress of chronic hepatitis C. Special emphasis is laid on the currently available possibilities of antiviral therapy and its future prospects. The efficacy of personalized treatment and approaches to its improvement are considered based on the proper preventive measures and correction of factors responsible for poor responsiveness to the treatment, in the first place metabolic disorders (obesity, hepatic steatosis).
authors.forename: N A
authors.initials: NA
authors.lastname: Mukhin
authors.forename: T M
authors.initials: TM
authors.lastname: Ignatova
authors.forename: D T
authors.initials: DT
authors.lastname: Abdurakhmanov
authors.forename: É Z
authors.initials: ÉZ
authors.lastname: Burnevich
authors.forename: T N
authors.initials: TN
authors.lastname: Lopatkina
authors.forename: T P
authors.initials: TP
authors.lastname: Rozina
authors.forename: E N
authors.initials: EN
authors.lastname: Nikulkina
mesh_terms: D000998:Antiviral Agents / Q000008:administration & dosage / Q000009:adverse effects; D018450:Disease Progression; D024882:Drug Resistance, Viral; D005234:Fatty Liver / Q000209:etiology / Q000473:pathology; D005260:Female; D016174:Hepacivirus / Q000302:isolation & purification / Q000472:pathogenicity; D019698:Hepatitis C, Chronic / Q000150:complications / Q000175:diagnosis / Q000209:etiology / Q000235:genetics / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008099:Liver / Q000473:pathology*; D008103:Liver Cirrhosis / Q000209:etiology / Q000473:pathology; D008111:Liver Function Tests / Q000379:methods*; D024821:Metabolic Syndrome / Q000150:complications / Q000378:metabolism; D008875:Middle Aged; D057285:Precision Medicine / Q000379:methods*; D065227:Transfusion Reaction; D016896:Treatment Outcome; D014766:Viremia / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D000998:Antiviral Agents