title: Hemoglobin SO-Arab and α-thalassemia diagnosed in an adult: A case-based review of the hemoglobinopathies.
abstract: Hemoglobin SO-Arab is a rare sickling disorder with a clinical course similar to that of hemoglobin SS. Hemoglobin C-Harlem is another rare condition that produces sickling disorders in affected individuals with a disease course and electrophoretic findings similar to that of hemoglobin SO-Arab. The authors report the case of a 38-year-old African American man with hemoglobin SO-Arab and the challenges that may arise in working up a rare hemoglobinopathy.
authors.affiliation: Departments of Internal Medicine (GZ), Section of Hematology & Oncology (GFM, BCB), and Pathology (FWB), Louisiana State University Health Sciences Center, New Orleans, Louisiana.
authors.forename: George
authors.initials: G
authors.lastname: Zacharia
authors.forename: Genevieve F
authors.initials: GF
authors.lastname: Maronge
authors.forename: Frederick W
authors.initials: FW
authors.lastname: Brazda
authors.forename: Brian C
authors.initials: BC
authors.lastname: Boulmay
mesh_terms: D000328:Adult; D001741:Black or African American; D000755:Anemia, Sickle Cell / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004586:Electrophoresis / Q000379:methods; D005821:Genetic Techniques; D006451:Hemoglobin, Sickle / Q000032:analysis; D006455:Hemoglobins, Abnormal / Q000032:analysis; D006579:Heterozygote; D006801:Humans; D008145:Louisiana; D008297:Male; D017085:alpha-Thalassemia / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism
chemical_list: D006451:Hemoglobin, Sickle; D006455:Hemoglobins, Abnormal; C032031:hemoglobin Arab