title: Beta-blocker therapy in unstable severe heart failure, evidence or experience?
abstract: Currently, no evidence exists on the effects of beta-receptor blocker (BRB) treatment in patients with unstable severe heart failure. When confronted with this specific patient category, clinical experience in our centre has consistently guided us to lower the dose or stop BRB therapy. To share this experience, we present three clinical case scenarios and discuss background literature motivating our approach in these patients.
authors.affiliation: Department of Cardiology, Utrecht Medical Centre, Utrecht, the Netherlands.
authors.forename: C L
authors.initials: CL
authors.lastname: Meuwese
authors.forename: J H
authors.initials: JH
authors.lastname: Kirkels
authors.forename: N
authors.initials: N
authors.lastname: de Jonge
authors.forename: H M
authors.initials: HM
authors.lastname: Nathoe
authors.forename: P A
authors.initials: PA
authors.lastname: Doevendans
authors.forename: C
authors.initials: C
authors.lastname: Klöpping