title: [A rare case of cystoid maculopathy].
abstract: We describe the case of a healthy 67-year-old Caucasian female who developed a rare, reversible case of cystoid maculopathy without late leak on fluorescein angiogram. She presented initially with a 5-year history of bilateral, variable central scotomata. The visual acuities were 6/6, while foveal reflexes were abnormal. Fluorescein angiogram showed no leakage; however, optical coherence tomography (OCT) revealed cystic spaces in the fovea of both eyes. The patient had been taking niacin supplements averaging 100mg daily for 30 years. Niacin was discontinued, and 7 months later, her symptoms and OCT results improved. Although niacin-induced maculopathy is uncommon, the clinician should enquire about possible niacin supplementation in any patient with cystoid macular edema in the absence of late leakage on fluorescein angiography. We describe a new reason for niacin maculopathy due to chronic low dose niacin supplementation and a slower pattern of visual recovery than that previously suggested in the literature.
authors.affiliation: Moorfields Eye Hospital, NHS Foundation Trust, 162, City Road, London, EC1V 2PD, Royaume-Uni. waheeda.rahman@moorfields.nhs.uk
authors.forename: W
authors.initials: W
authors.lastname: Rahman
authors.forename: M-H
authors.initials: MH
authors.lastname: Errera
authors.forename: C
authors.initials: C
authors.lastname: Egan
mesh_terms: D000368:Aged; D019587:Dietary Supplements / Q000009:adverse effects; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008269:Macular Edema / Q000139:chemically induced* / Q000175:diagnosis*; D009525:Niacin / Q000009:adverse effects*
chemical_list: D009525:Niacin