title: Diversity of HLA-B*35 alleles and haplotypes among Croatians.
abstract: OBJECTIVE
  Investigation of HLA-B*35 subtypes and haplotypes among Croatians.
  
  
  METHODS
  4000 randomly selected unrelated donors from Croatian Bone Marrow Donor Registry were typed for HLA-A, -B and -DRB1 by PCR-LabType®SSO method.
  
  
  RESULTS
  Four different B*35 alleles (*35:01, *35:02, *35:03, *35:08) were found. Three of them were with similar frequencies as in other European Caucasians, while HLA-B*35:03 was two times more frequent in our population. Predicted haplotypes were also in accordance with present data from other populations.
  
  
  CONCLUSIONS
  This study should be of benefit in the unrelated haematopoietic stem cell transplantation (HSCT) program. It should facilitate the recipient-donor matching and the selection of a suitable population for further searches.
authors.affiliation: Clinical Units for Tissue Typing, Clinical Department for Transfusion Medicine and Transplantation Biology, University Hospital Centre Zagreb, Zagreb, Croatia.
authors.forename: Marija
authors.initials: M
authors.lastname: Calusic
authors.forename: Zorana
authors.initials: Z
authors.lastname: Grubic
authors.forename: Katarina
authors.initials: K
authors.lastname: Stingl
authors.forename: Marija Burek
authors.initials: MB
authors.lastname: Kamenaric
authors.forename: Renata
authors.initials: R
authors.lastname: Zunec
mesh_terms: D016026:Bone Marrow Transplantation; D017523:Croatia; D005787:Gene Frequency; D015797:HLA-B35 Antigen / Q000235:genetics*; D006239:Haplotypes; D018380:Hematopoietic Stem Cell Transplantation; D006648:Histocompatibility; D006650:Histocompatibility Testing; D006801:Humans; D015810:Linkage Disequilibrium; D011110:Polymorphism, Genetic; D012042:Registries; D061349:Unrelated Donors; D044465:White People / Q000235:genetics
chemical_list: D015797:HLA-B35 Antigen