title: Monte Carlo simulations shed light on Bathsheba's suspect breast.
abstract: In 1654, Rembrandt van Rijn painted his famous painting Bathsheba at her Bath. Over the years, the depiction of Bathsheba's left breast and especially the presence of local discoloration, has generated debate on whether Rembrandt's Bathsheba suffered from breast cancer. Historical, medical and artistic arguments appeared to be not sufficient to prove if Bathsheba's model truly suffered from breast cancer. However, the bluish discoloration of the breast is an intriguing aspect from a biomedical optics point of view that might help us ending the old debate. By using Monte Carlo simulations in combination with the retinex theory of color vision, we showed that is highly unlikely that breast cancer results in a local bluish discoloration of the skin as is present on Bathsheba's breast.
authors.affiliation: Biomedical Photonic Imaging Group, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, P.O. Box 217, 7500 AE Enschede, the Netherlands; Center for Breast Care, Medisch Spectrum Twente hospital, P.O. Box 50000, 7500 KA, Enschede, the Netherlands. m.heijblom@utwente.nl.
authors.forename: Michelle
authors.initials: M
authors.lastname: Heijblom
authors.forename: Linda M
authors.initials: LM
authors.lastname: Meijer
authors.forename: Ton G
authors.initials: TG
authors.lastname: van Leeuwen
authors.forename: Wiendelt
authors.initials: W
authors.lastname: Steenbergen
authors.forename: Srirang
authors.initials: S
authors.lastname: Manohar
mesh_terms: D001940:Breast / Q000098:blood supply*; D001943:Breast Neoplasms / Q000098:blood supply / Q000175:diagnosis; D055253:Color Vision; D005260:Female; D006801:Humans; D009010:Monte Carlo Method; D010151:Paintings; D012880:Skin Pigmentation; D014680:Veins / Q000473:pathology; D014796:Visual Perception