title: Acute care utilization due to hospitalizations for pediatric lower respiratory tract infections in British Columbia, Canada.
abstract: BACKGROUND
  Pediatric LRTI hospitalizations are a significant burden on patients, families, and healthcare systems. This study determined the burden of pediatric LRTIs on hospital settings in British Columbia and the benefits of prevention strategies as they relate to healthcare resource demand.
  
  
  METHODS
  LRTI inpatient episodes for patients <19 years of age during 2008-2010 were extracted from the BC Discharge Abstract Database. The annual number of acute care beds required to treat pediatric LRTIs was estimated. Sub-analyses determined the burden due to infants <1 year of age and high-risk infants. Population projections were used to forecast LRTI hospitalizations and the effectiveness of public health initiatives to reduce the incidence of LRTIs to 2020 and 2030.
  
  
  RESULTS
  During 2008-2010, LRTI as the primary diagnosis accounted for 32.0 and 75.9% hospitalizations for diseases of the respiratory system in children <19 years of age and infants <1 year of age, respectively. Infants <1 year of age accounted for 47 and 77% hospitalizations due to pediatric LRTIs and pediatric LRTI hospitalizations specifically due to respiratory syncytial virus (RSV), respectively. The average length of stay was 3.1 days for otherwise healthy infants <1 year of age and 9.1 days for high-risk infants (P <0.0001). 73.1% pediatric LRTI hospitalizations occurred between November and April. Over the study timeframe, 19.6 acute care beds were required on average to care for pediatric LRTIs which increased to 64.0 beds at the peak of LRTI hospitalizations. Increases in LRTI bed-days of 5.5 and 16.2% among <19 year olds by 2020 and 2030, respectively, were predicted. Implementation of appropriate prevention strategies could cause 307 and 338 less LRTI hospitalizations in <19 year olds in 2020 and 2030, respectively.
  
  
  CONCLUSIONS
  Pediatric LRTI hospitalizations require significant use of acute care infrastructure particularly between November and April. Population projections show the burden may increase in the next 20 years, but implementation of effective public health prevention strategies may contribute to reducing the acute care demand and to supporting efforts for overall pediatric healthcare sustainability.
authors.affiliation: Abbott Laboratories, 200 Abbott Park Road, Abbott Park, IL 60064, USA.
authors.forename: Pablo
authors.initials: P
authors.lastname: Santibanez
authors.forename: Katherine
authors.initials: K
authors.lastname: Gooch
authors.forename: Pamela
authors.initials: P
authors.lastname: Vo
authors.forename: Michelle
authors.initials: M
authors.lastname: Lorimer
authors.forename: Yurik
authors.initials: Y
authors.lastname: Sandino
mesh_terms: D000293:Adolescent; D001955:British Columbia / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D016001:Confidence Intervals; D003422:Critical Care / Q000706:statistics & numerical data*; D016208:Databases, Factual; D017048:Health Care Costs; D006760:Hospitalization / Q000639:trends*; D006801:Humans; D007223:Infant; D007902:Length of Stay / Q000639:trends; D012141:Respiratory Tract Infections / Q000145:classification / Q000453:epidemiology / Q000628:therapy*