title: The relationship between psychosocial stress and allergic disease among children and adolescents in Gwangyang Bay, Korea.
abstract: OBJECTIVE
  Stress is considered a causal factor in many diseases, allergic disease being one of them. The prevalence of allergic disease is increasing in Korea, but the relationship between allergic symptoms and stress is not empirically well known. We aimed to evaluate the relationship between allergy-related symptoms and stress in children and adolescents.
  
  
  METHODS
  We investigated 698 children and adolescents living in Gwangyang Bay, Korea, using a multi-stage cluster sampling method. Using the International Study of Asthma and Allergies in Childhood and the Psychosocial Well-being Index, these subjects were surveyed on allergy-related symptoms and psychosocial stressors in their lives, respectively. We used a multivariate logistic analysis for odds ratios for the complaint rate of allergic symptoms, after adjusting for age, gender, household income, body mass index, and residence.
  
  
  RESULTS
  After adjustments, lifetime rhinitis (odds ratio [OR], 1.024), rhinoconjunctivitis (OR, 1.090), diagnosis of itchy eczema (OR, 1.040), treatment of itchy eczema (OR, 1.049), 12-month allergic conjunctivitis (OR, 1.026), diagnosis of allergic conjunctivitis (OR, 1.031), and treatment of allergic conjunctivitis (OR, 1.034) were found to be significantly associated with stress.
  
  
  CONCLUSIONS
  Our results support the notion that there is a relationship between stress and allergic symptoms in children and adolescents. Further research into any causal relationship between stress and allergies, as well as preventative public health plans for decreasing stress in children and adolescents are needed.
authors.affiliation: Department of Preventive Medicine & Institute of Environmental and Occupational Medicine, Soonchunhyang University College of Medicine, Cheonan, Korea.
authors.forename: Mee-Ri
authors.initials: MR
authors.lastname: Lee
authors.forename: Bu-Soon
authors.initials: BS
authors.lastname: Son
authors.forename: Yoo-Ri
authors.initials: YR
authors.lastname: Park
authors.forename: Hye-Mi
authors.initials: HM
authors.lastname: Kim
authors.forename: Jong-Youn
authors.initials: JY
authors.lastname: Moon
authors.forename: Yong-Jin
authors.initials: YJ
authors.lastname: Lee
authors.forename: Yong-Bae
authors.initials: YB
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D002648:Child; D016000:Cluster Analysis; D003233:Conjunctivitis, Allergic / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D003430:Cross-Sectional Studies; D004485:Eczema / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*; D007407:Interviews as Topic; D016015:Logistic Models; D008297:Male; D056910:Republic of Korea; D012220:Rhinitis / Q000175:diagnosis / Q000523:psychology; D013315:Stress, Psychological; D011795:Surveys and Questionnaires