title: Coil embolization of an intracranial aneurysm in an infant with tuberous sclerosis complex: A case report and literature review.
abstract: BACKGROUND
  Tuberous sclerosis (TS) is a multiorgan neurocutaneous syndrome. Vascular manifestations are often extracranial. There is a paucity of cases involving TS combined with intracranial aneurysms reported in the literature. As a result, treatment has not been well described.
  
  
  METHODS
  We report the case of a 13-month-old female infant with a prior diagnosis of TS that was found to have new onset of left eye ptosis, anisocoria, and papillary mydriasis indicative of left third cranial nerve palsy. A magnetic resonance angiogram (MRA) of the brain revealed a left internal carotid artery (ICA) aneurysm. Endovascular embolization was determined to be the best option for treatment. After a successful balloon test occlusion with neuromonitoring, the left internal carotid artery was sacrificed via coil embolization.
  
  
  CONCLUSIONS
  This is only the third case report of endovascular coil embolization of an intracranial aneurysm in an infant with TS. We report no complications during the procedure, and the patient was discharged with resolving left third cranial nerve palsy. Neither surgical nor endovascular outcomes have been well described in the literature. Follow-up on this patient will be useful for establishing protocols of treatment.
authors.affiliation: Department of Neurosurgery, SUNY Upstate Medical University, Syracuse, NY, USA.
authors.forename: Juneyoung L
authors.initials: JL
authors.lastname: Yi
authors.forename: Michael A
authors.initials: MA
authors.lastname: Galgano
authors.forename: Zulma
authors.initials: Z
authors.lastname: Tovar-Spinoza
authors.forename: Eric M
authors.initials: EM
authors.lastname: Deshaies