title: [Roles of cardiovascular disease in obstructive sleep apnea hypopnea syndrome].
abstract: OBJECTIVE
  To explore the roles of cardiovascular disease in obstructive sleep apnea hypopnea syndrome.
  
  
  METHODS
  All 228 OSAHS patients underwent the examination of biochemical and complete blood count. The correlation analysis between AHI, AI, HI, LSaO2, complete blood count, and biochemical examination were employed. Two hundred and twenty-eight cases were divided into 3 groups according to sleep apnea hypopnea index (AHI): group 1 (5 < or = AHI < 15), group 2 (15 < or = AHI < 30), group 3 (30 < or = AHI). Morbidity of diseases in each group was calculated and the value of AHI and AI for morbidity was analyzed by using ROC curve.
  
  
  RESULTS
  (1) No statistically significant difference was found between group 1 and group 2 (chi2 = 0.428, P > 0.05). There was significant difference between group 3 and group 1, 2 (chi2 = 12.89, P < 0.05). The areas under the ROC curves of AHI and AI were 0. 678 and 0. 679,respectively. (2) There was significant positive correlation between AHI and complete blood count parameters (r = 0.176 to 0.194, P < 0.05).
  
  
  CONCLUSIONS
  OSAHS may be one of the predisposing factors of cardiovascular disease.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Navy General Hospital, Beijing, 100048, China.
authors.forename: Xi
authors.initials: X
authors.lastname: Chen
authors.forename: Jinrang
authors.initials: J
authors.lastname: Li
authors.forename: Jianjun
authors.initials: J
authors.lastname: Sun
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D055815:Young Adult