title: Vaginal toxic shock reaction triggering desquamative inflammatory vaginitis.
abstract: OBJECTIVE
  The study aimed to report 2 cases of desquamative inflammatory vaginitis associated with toxic shock syndrome toxin 1 (TSST-1)-producing Staphylococcus aureus strains.
  
  
  METHODS
  Case report of 2 patients, 1 with an acute and 1 with a chronic presentation, diagnosed with desquamative inflammatory vaginitis on the basis of clinical findings and wet mount microscopy. Pretreatment and posttreatment vaginal bacterial and yeast cultures were obtained.
  
  
  RESULTS
  Pretreatment vaginal bacterial cultures from both patients grew TSST-1-producing S. aureus. Subsequent vaginal bacterial culture results after oral antibiotic therapy were negative.
  
  
  CONCLUSIONS
  Desquamative inflammatory vaginitis may be triggered through TSST-1-mediated vaginal toxic shock reaction.
authors.affiliation: Departments of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, PA 19102, USA. Nigel.Pereira@drexelmed.edu
authors.forename: Nigel
authors.initials: N
authors.lastname: Pereira
authors.forename: Thomas D
authors.initials: TD
authors.lastname: Edlind
authors.forename: Patrick M
authors.initials: PM
authors.lastname: Schlievert
authors.forename: Paul
authors.initials: P
authors.lastname: Nyirjesy
mesh_terms: D000328:Adult; D001427:Bacterial Toxins; D004768:Enterotoxins / Q000378:metabolism; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D008853:Microscopy; D008875:Middle Aged; D012772:Shock, Septic / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D013203:Staphylococcal Infections / Q000175:diagnosis* / Q000473:pathology*; D013211:Staphylococcus aureus / Q000302:isolation & purification* / Q000472:pathogenicity; D018089:Superantigens; D014627:Vaginitis / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal