title: [Systemic and oropharyngeal side effects of inhaled corticosteroids].
abstract: The use of inhaled corticosteroids (ICS) is an important component of asthma management. Although their main impact is on airway inflammation, ICS are not devoid of systemic side effects (adrenal insufficiency, osteoporosis, brittle skin, ocular effects, growth retardation). Oropharyngeal side effects are also reported. These effects appear dose and duration dependent. They also vary according to the type of ICS used, its method of administration and drug interactions. It is recommended to titrate ICS to the lowest effective dose, to regularly reconsider their indication and to be aware of drug interactions. In addition, a change in ICS may have a favorable impact on side effects.
authors.affiliation: Service de médecine interne générale, HUG, 1211 Genève 14. tamara.rochat@hcuge.ch
authors.forename: T S
authors.initials: TS
authors.lastname: Rochat
authors.forename: J-P
authors.initials: JP
authors.lastname: Janssens
mesh_terms: D000280:Administration, Inhalation; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D009960:Oropharynx / Q000187:drug effects / Q000473:pathology; D010608:Pharyngeal Diseases / Q000139:chemically induced; D013997:Time Factors
chemical_list: D018927:Anti-Asthmatic Agents; D005938:Glucocorticoids