title: [Parenchymal complications of the transplanted kidney: the role of color-Doppler imaging].
abstract: Kidney transplantation is the treatment of choice for end-stage renal disease, given the better quality of life of transplanted patients when compared to patients on maintenance dialysis. In spite of surgical improvements and new immunosuppressive regimens, part of the transplanted grafts still develop chronic dysfunction. Ultrasonography, both in B-mode and with Doppler ultrasound, is an important diagnostic tool in case of clinical conditions which might impair kidney function. Even though ultrasonography is considered fundamental in the diagnosis of vascular and surgical complications of the transplanted kidney, its role is not fully understood in case of parenchymal complications of the graft. The specificity of Doppler ultrasound is low both in case of acute complications such as acute tubular necrosis, drug toxicity and acute rejection, and in case of chronic conditions such as chronic allograft nephropathy. Single determinations of resistance indices present low diagnostic accuracy, which is higher in case of successive measurements performed during the follow-up of the graft. Modern techniques including tissue pulsatility index, maximal fractional area and contrast-enhanced ultrasound increase the diagnostic power of ultrasonography in case of parenchymal complications of the transplanted kidney.
authors.affiliation: U.O.C. Nefrologia e Dialisi, Ospedale San Giovanni di Dio, Agrigento, Italy. antonio.granata4@tin.it
authors.forename: Antonio
authors.initials: A
authors.lastname: Granata
authors.forename: Silvia
authors.initials: S
authors.lastname: Clementi
authors.forename: Anna
authors.initials: A
authors.lastname: Clementi
authors.forename: Fabio
authors.initials: F
authors.lastname: Di Pietro
authors.forename: Viviana R
authors.initials: VR
authors.lastname: Scarfia
authors.forename: Monica
authors.initials: M
authors.lastname: Insalaco
authors.forename: Filippo
authors.initials: F
authors.lastname: Aucella
authors.forename: Michele
authors.initials: M
authors.lastname: Prencipe
authors.forename: Fulvio
authors.initials: F
authors.lastname: Fiorini
authors.forename: Elvia
authors.initials: E
authors.lastname: Sicurezza
mesh_terms: D000208:Acute Disease; D002908:Chronic Disease; D006084:Graft Rejection / Q000000981:diagnostic imaging; D006801:Humans; D007674:Kidney Diseases / Q000000981:diagnostic imaging* / Q000209:etiology*; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000000981:diagnostic imaging*; D007683:Kidney Tubular Necrosis, Acute / Q000000981:diagnostic imaging / Q000209:etiology; D018615:Ultrasonography, Doppler, Color