title: [Prion diseases].
abstract: Prion diseases are a family of progressive neurodegenerative disorders caused by prions. There are four human prion diseases: Creutzfeldt-Jakob disease, Gerstmann-Straussler-Scheinker syndrome, fatal insomnia and Kuru. They can arise in three different ways: acquired, familial or sporadic. We review clinical presentations, pathophysiology, morphological picture, diagnostic procedures and available treatment options of prion diseases.
authors.forename: N I
authors.initials: NI
authors.lastname: Stoĭda
authors.forename: I A
authors.initials: IA
authors.lastname: Zavalishin
mesh_terms: D004569:Electroencephalography; D006801:Humans; D018621:PrPC Proteins / Q000378:metabolism; D017096:Prion Diseases / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D000072002:Prion Proteins; D011328:Prions / Q000235:genetics / Q000378:metabolism; D059748:Proteolysis
chemical_list: C512656:PRNP protein, human; D018621:PrPC Proteins; D000072002:Prion Proteins; D011328:Prions