title: [Ethylene glycol poisoning--the significance of analytical diagnosis based on reports from Wielkopolska].
abstract: Ethylene glycol (EG) is a multidirectional, dihydric alcohol, which is widely used in food, chemical and automotive industries. EG is a compound of similar toxicity to ethanol (EA). The EG biotransformation undergoes, mainly to glycolaldehyde and acids: glycolic, glyoxylic and oxalic acid, such metabolites, which exhibit strong narcotic effect on the central nervous system, causing profound metabolic acidosis and lead to severe nephropathy. Due to the wide availability of products containing ethylene glycol and its potential toxicity, in the case of the alcohol poisoning, the significant role in the diagnosis play: medical interview, observation of characteristic clinical symptoms, basic laboratory tests and detection of ethylene glycol in the biological material that confirm EG poisoning.
authors.affiliation: Katedra i Zakład Toksykologii, Uniwersytet Medyczny im. K. Marcinkowskiego w Poznaniu.
authors.forename: Karina
authors.initials: K
authors.lastname: Sommerfeld
authors.forename: Magdalena
authors.initials: M
authors.lastname: Łukasik-Głebocka
authors.forename: Barbara
authors.initials: B
authors.lastname: Zielińska-Psuja
mesh_terms: D000328:Adult; D000368:Aged; D062787:Drug Overdose / Q000175:diagnosis*; D019855:Ethylene Glycol / Q000032:analysis* / Q000506:poisoning*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D019855:Ethylene Glycol