title: Lack of adequate predialyis care and previous hemodialysis, but not hemoglobin variability, are independent predictors of anemia-associated mortality in incident Brazilian peritoneal dialysis patients: results from the BRAZPD study.
abstract: OBJECTIVE
  The objective of this study was to analyze the prevalence of anemia and variability of hemoglobin (Hb) values in peritoneal dialysis (PD) patients, to establish its associated factors and their impact on clinical outcomes in a large cohort of patients starting PD treatment.
  
  
  METHODS
  Data were collected monthly in incident patients, who were followed until the primary endpoint (death from all causes) or until leaving the study.
  
  
  RESULTS
  2,156 patients starting PD were included. The prevalence of Hb lower than 11 g/dl was 57% at baseline and decreased to 38% at the 4th month. Lack of adequate predialysis care and previous treatment with hemodialysis were the most important factors associated with anemia. Anemia was an independent predictor of mortality. There were no differences in patient survival throughout the different groups of Hb variability.
  
  
  CONCLUSIONS
  Our data point to the need of identifying other risk factors for anemia and aggressively interfere with the modifiable ones in order to correct anemia and decrease mortality in this group of high-risk patients.
authors.affiliation: School of Medicine, Pontificia Universidade Catolica do Parana, Curitiba, Brazil.
authors.forename: Simone M
authors.initials: SM
authors.lastname: Gonçalves
authors.forename: Eduardo Andreazza
authors.initials: EA
authors.lastname: Dal Lago
authors.forename: Thyago P
authors.initials: TP
authors.lastname: de Moraes
authors.forename: Sandra Contador
authors.initials: SC
authors.lastname: Kloster
authors.forename: Gustavo
authors.initials: G
authors.lastname: Boros
authors.forename: Milena
authors.initials: M
authors.lastname: Colombo
authors.forename: Lenisa
authors.initials: L
authors.lastname: Raboni
authors.forename: Márcia
authors.initials: M
authors.lastname: Olandoski
authors.forename: Natália
authors.initials: N
authors.lastname: Fernandes
authors.forename: Abdul Rashid
authors.initials: AR
authors.lastname: Qureshi
authors.forename: José Carolino
authors.initials: JC
authors.lastname: Divino Filho
authors.forename: Roberto
authors.initials: R
authors.lastname: Pecoits-Filho
mesh_terms: D000328:Adult; D000368:Aged; D000740:Anemia / Q000453:epidemiology* / Q000209:etiology* / Q000401:mortality; D001938:Brazil / Q000453:epidemiology; D005260:Female; D005293:Ferritins / Q000097:blood; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000150:complications* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D011379:Prognosis; D012307:Risk Factors
chemical_list: D006454:Hemoglobins; D005293:Ferritins