title: Isolated pulmonary amyloidomas: report of 3 cases with histologic and imaging findings.
abstract: Amyloid tumors presenting as lung masses are rare. We report 3 patients seen over a 2-year period with multiple lung masses, 2 that were suspicious for metastasis, and one in a patient with chest pain. Pathologic evaluation demonstrated amyloid tumor in each case. Two demonstrated a prominent macrophage giant cell reaction; scattered polyclonal plasma cells were present in two of the cases. PET scanning of 2 of the patients revealed an SUV of 1.9 and 4.0, respectively. Short-term follow-up revealed that none of the 3 cases were associated with lymphoproliferative disorders. This small series and a literature review suggest that pulmonary amyloidomas are usually isolated lesions, and that PET may show increased uptake simulating a neoplasm.
authors.affiliation: Department of Pathology and Radiology, University of Maryland Medical Center, Baltimore, MD, USA.
authors.forename: Lauren
authors.initials: L
authors.lastname: Xu
authors.forename: Aletta
authors.initials: A
authors.lastname: Frazier
authors.forename: Allen
authors.initials: A
authors.lastname: Burke
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000473:pathology*; D008297:Male; D008875:Middle Aged