title: [Antibiotic ointments and methicillin-resistant Staphylococcus aureus with a reservoir in a healthcare worker in a tertiary hospital].
abstract: BACKGROUND
  Methicillin-resistant Staphylococcus aureus (MRSA) has become an important hospital-acquired pathogen, with transfer of the organism from a carrier or infected patient to uninfected patients by the hands or clothing of staff as the main mode of transmission.
  
  
  METHODS
  Investigation of a cluster of new cases of MRSA resistant to mupirocin and fusidic acid, using epidemiological and microbiological resources.
  
  
  RESULTS
  From September 2010 to February 2012, sixteen patients had at least one culture positive for MRSA resistant to mupirocin and fusidic acid. Some not apparently related cases and outbreaks appeared. By analysing cultures taken from patients and staff using pulsed-field gel electrophoresis, it was demonstrated that most likely this situation was started by an auxiliary nurse who was a carrier of the MRSA. Healthcare worker decontamination using oral antibiotic therapy was unsuccessful. Eventually, the situation was controlled by placing the carrier in a different job, with no further cases to date (September, 2012).
  
  
  CONCLUSIONS
  This report illustrates the risk of nosocomial transmission linked to care delivered by healthcare workers.
authors.affiliation: Servicio de Medicina Preventiva, Complejo Hospitalario Universitario Insular-Materno Infantil (CHUIMI), Las Palmas de Gran Canaria, España. Electronic address: jmolcab@gobiernodecanarias.org.
authors.forename: Jesús
authors.initials: J
authors.lastname: Molina-Cabrillana
authors.forename: Cristóbal
authors.initials: C
authors.lastname: Del Rosario-Quintana
authors.forename: Tomas
authors.initials: T
authors.lastname: Tosco-Núñez
authors.forename: Elena
authors.initials: E
authors.lastname: Dorta-Hung
authors.forename: Anna
authors.initials: A
authors.lastname: Quori
authors.forename: Antonio M
authors.initials: AM
authors.lastname: Martín-Sánchez
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D015373:Bacterial Typing Techniques; D002353:Carrier State / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission*; D004196:Disease Outbreaks; D004197:Disease Reservoirs / Q000382:microbiology*; D024901:Drug Resistance, Multiple, Bacterial; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D005672:Fusidic Acid / Q000494:pharmacology; D006801:Humans; D015994:Incidence; D017757:Infectious Disease Transmission, Professional-to-Patient / Q000517:prevention & control; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D016712:Mupirocin / Q000494:pharmacology; D009296:Nasal Cavity / Q000382:microbiology; D009728:Nursing Assistants; D009824:Ointments; D010564:Personnel, Hospital; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D062606:Tertiary Care Centers
chemical_list: D000900:Anti-Bacterial Agents; D009824:Ointments; D005672:Fusidic Acid; D016712:Mupirocin