title: [Intensive therapy of severe community-acquired pneumonia].
abstract: The purpose of the study was to improve efficiency of treatment of the patients with severe community-acquired pneumonia at the expense of optimization of schemes of intensive therapy using immunomodulators, antioxidants and antihypoxants.  The study involved 142 patients with severe community-acquired pneumonia who were divided into 4 groups. The properties of the erythrocytes membranes, some indicators of immune system and endotoxicosis were examined.   It has been determined, that the use of Cycloferonum increases the functionale state of active link of T-immunity. It has been established that the use of Reamberinum while applying the complex therapy results in accelerating the normalization of endotoxicosis indices, it favourably effects the properties of the erythrocytes membranes.  The positive influence of Cycloferonum and Reamberinum has been proved. The inclusion of the preparations Reamberinum and Cycloferonum into the complex of intensive therapy to the patients with severe community-acquired pneumonia reduces the bed-staying at the department of intensive care unit.
authors.forename: R E
authors.initials: RE
authors.lastname: Rzheutskaia
mesh_terms: D000166:Acridines / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology; D003131:Combined Modality Therapy; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000276:immunology / Q000628:therapy*; D003422:Critical Care; D005260:Female; D006801:Humans; D007369:Interferon Inducers / Q000627:therapeutic use; D018655:Lymphocyte Count; D008297:Male; D008536:Meglumine / Q000031:analogs & derivatives / Q000627:therapeutic use; D008875:Middle Aged; D018410:Pneumonia, Bacterial / Q000453:epidemiology / Q000276:immunology / Q000628:therapy*; D002094:Republic of Belarus / Q000453:epidemiology; D013386:Succinates / Q000627:therapeutic use; D013601:T-Lymphocytes / Q000276:immunology; D055815:Young Adult
chemical_list: D000166:Acridines; D007369:Interferon Inducers; C549374:Reamberin; D013386:Succinates; D008536:Meglumine; C026430:10-carboxymethyl-9-acridanone