title: Application of the optical method in experimental cardiology: action potential and intracellular calcium concentration measurement.
abstract: It has been shown that, in addition to conventional contact electrode techniques, optical methods using fluorescent dyes can be successfully used for cardiac signal measurement. In this review, the physical and technical fundamentals of the method are described, as well as the properties of the most common systems for measuring action potentials and intracellular calcium concentration. Special attention is paid to summarizing limitations and trends in developing this method.
authors.affiliation: Department of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology, Brno, Czech Republic. ronzhina@feec.vutbr.cz
authors.forename: M
authors.initials: M
authors.lastname: Ronzhina
authors.forename: V
authors.initials: V
authors.lastname: Cmiel
authors.forename: O
authors.initials: O
authors.lastname: Janoušek
authors.forename: J
authors.initials: J
authors.lastname: Kolářová
authors.forename: M
authors.initials: M
authors.lastname: Nováková
authors.forename: P
authors.initials: P
authors.lastname: Babula
authors.forename: I
authors.initials: I
authors.lastname: Provazník
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D002118:Calcium / Q000378:metabolism* / Q000502:physiology*; D020013:Calcium Signaling / Q000502:physiology; D002309:Cardiology / Q000379:methods*; D055724:Electrophysiological Phenomena; D005456:Fluorescent Dyes; D006321:Heart / Q000502:physiology*; D006801:Humans
chemical_list: D005456:Fluorescent Dyes; D002118:Calcium