title: Determination of phthalate esters in polyvinyl chloride infusion bag by stir bar sorptive extraction combined with GC.
abstract: A novel, efficient, and sensitive stir bar sorptive extraction method coupled with GC for the detection of four kinds of phthalate esters in plasticized polyvinyl chloride infusion bag has been developed and validated. Some experimental parameters including stirring speed, stirring time, pH value, salt concentration, desorption mode, desorption solvents, and desorption time were investigated and optimized. Under optimum condition, the validated assay was found to be linear (r > 0.9945) and LODs were between 1.07 and 2.67 ng for the four analytes. The method exhibited excellent precision with RSD varied from 4.5 to 6.1% (n = 5). The recoveries of the four phthalate esters at two different concentrations ranged from 80.5 to 93.4%. The results showed that the validated method could meet the need of determination of targets and was successfully applied to the analysis of phthalate esters in real samples.
authors.affiliation: School of Pharmacy, Shenyang Pharmaceutical University, PR China.
authors.forename: Meng
authors.initials: M
authors.lastname: Sun
authors.forename: Jinna
authors.initials: J
authors.lastname: Dai
authors.forename: Xiaofan
authors.initials: X
authors.lastname: Wang
authors.forename: Xu
authors.initials: X
authors.lastname: Zhao
authors.forename: Kaishun
authors.initials: K
authors.lastname: Bi
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Chen
mesh_terms: D002849:Chromatography, Gas / Q000379:methods*; D004952:Esters; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D010795:Phthalic Acids / Q000032:analysis* / Q000737:chemistry; D011143:Polyvinyl Chloride / Q000737:chemistry*; D015203:Reproducibility of Results
chemical_list: D004952:Esters; D010795:Phthalic Acids; C032279:phthalic acid; D011143:Polyvinyl Chloride