title: Development of implant loading device for animal study about various loading protocol: a pilot study.
abstract: OBJECTIVE
  The aims of this pilot study were to introduce implant loading devices designed for animal study and to evaluate the validity of the load transmission ability of the loading devices.
  
  
  METHODS
  Implant loading devices were specially designed and fabricated with two implant abutments and cast metal bars, and orthodontic expansion screw. In six Beagles, all premolars were extracted and two implants were placed in each side of the mandibles. The loading device was inserted two weeks after the implant placement. According to the loading protocol, the load was applied to the implants with different time and method,simulating early, progressive, and delayed loading. The implants were clinically evaluated and the loading devices were removed and replaced to the master cast, followed by stress-strain analysis. Descriptive statistics of remained strain (µε) was evaluated after repeating three cycles of the loading device activation. Statistic analysis was performed using nonparametric, independent t-test with 5% significance level and Friedman's test was also used for verification.
  
  
  RESULTS
  The loading devices were in good action. However, four implants in three Beagles showed loss of osseointegration. In stress-strain analysis, loading devices showed similar amount of increase in the remained strain after applying 1-unit load for three times.
  
  
  CONCLUSIONS
  Specialized design of the implant loading device was introduced. The loading device applied similar amount of loads near the implant after each 1-unit loading. However, the direction of the loads was not parallel to the long axis of the implants as predicted before the study.
authors.affiliation: Department of Prosthodontics, Yonsei University College of Dentistry, Seoul, Korea.
authors.forename: Joon-Ho
authors.initials: JH
authors.lastname: Yoon
authors.forename: Young-Bum
authors.initials: YB
authors.lastname: Park
authors.forename: Yuna
authors.initials: Y
authors.lastname: Cho
authors.forename: Chang-Sung
authors.initials: CS
authors.lastname: Kim
authors.forename: Seong-Ho
authors.initials: SH
authors.lastname: Choi
authors.forename: Hong-Seok
authors.initials: HS
authors.lastname: Moon
authors.forename: Keun-Woo
authors.initials: KW
authors.lastname: Lee
authors.forename: June-Sung
authors.initials: JS
authors.lastname: Shim