title: An outbreak of trichinosis with molecular identification of Trichinella sp. in Vietnam.
abstract: The 5th outbreak of trichinosis occurred in a mountainous area of North Vietnam in 2012, involving 24 patients among 27 people who consumed raw pork together. Six of these patients visited several hospitals in Hanoi for treatment. Similar clinical symptoms appeared in these patients within 5-8 days after eating infected raw pork, which consisted of fever, muscle pain, difficult moving, edema, difficult swallowing, and difficult breathing. ELISA revealed all (6/6) positive reactions against Trichinella spiralis antigen and all cases showed positive biopsy results for Trichinella sp. larvae in the muscle. The larvae detected in the patients were identified as T. spiralis (Vietnamese strain) by the molecular analysis of the mitochondrial cytochrome c oxidase subunit III (cox3) gene.
authors.affiliation: Department of Parasitology, Hanoi Medical University, Vietnam. ngvdeyhn@gmail.com
authors.forename: Nguyen
authors.initials: N
authors.lastname: Van De
authors.forename: Nguyen Vu
authors.initials: NV
authors.lastname: Trung
authors.forename: Nguyen Hong
authors.initials: NH
authors.lastname: Ha
authors.forename: Vu Thi
authors.initials: VT
authors.lastname: Nga
authors.forename: Nguyen Minh
authors.initials: NM
authors.lastname: Ha
authors.forename: Pham Thanh
authors.initials: PT
authors.lastname: Thuy
authors.forename: Le Van
authors.initials: le V
authors.lastname: Duyet
authors.forename: Jong-Yil
authors.initials: JY
authors.lastname: Chai
mesh_terms: D000328:Adult; D000818:Animals; D000947:Antigens, Helminth / Q000032:analysis / Q000276:immunology; D004196:Disease Outbreaks; D003576:Electron Transport Complex IV / Q000235:genetics; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007814:Larva; D008297:Male; D008460:Meat / Q000469:parasitology*; D008928:Mitochondria / Q000235:genetics; D009132:Muscles / Q000469:parasitology / Q000473:pathology; D013552:Swine; D017160:Trichinella spiralis / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D014235:Trichinellosis / Q000453:epidemiology* / Q000469:parasitology / Q000473:pathology; D014744:Vietnam / Q000453:epidemiology
chemical_list: D000947:Antigens, Helminth; D003576:Electron Transport Complex IV