title: [Fatal coronary artery spasm in a patient with thyrotoxicosis].
abstract: According to some data up to 20% of patients with thyrotoxicosis suffer from vasospastic angina. But  presence of coronary artery spasm can be rarely confirmed. We describe a case of development of spasm of coronary arteries in a patients with severe thyrotoxicosis. Despite active treatment of thyrotoxicosis and use of drugs aimed at prevention of coronary spasm this patient with minor changes in coronary arteries (according to autopsy data) developed episode of acute myocardial ischemia leading to lethal outcome. This clinical case shows that patients with thyrotoxicosis and documented transitory myocardial ischemia should receive therapy with thyrostatics and drugs preventing coronary spasm in maximal doses until stable normalization of levels of thyroid hormones.
authors.forename: I I
authors.initials: II
authors.lastname: Dedov
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Kalashnikov
authors.forename: S A
authors.initials: SA
authors.lastname: Terekhin
authors.forename: E N
authors.initials: EN
authors.lastname: Golovenko
authors.forename: N Iu
authors.initials: NIu
authors.lastname: Sviridenko
authors.forename: K V
authors.initials: KV
authors.lastname: Melkozerov
authors.forename: A A
authors.initials: AA
authors.lastname: Parfenenkova
authors.forename: F Iu
authors.initials: FIu
authors.lastname: Kopylov
authors.forename: A V
authors.initials: AV
authors.lastname: Gribanova
mesh_terms: D013956:Antithyroid Agents / Q000008:administration & dosage*; D001281:Atrial Fibrillation / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D002317:Cardiovascular Agents / Q000008:administration & dosage*; D017023:Coronary Angiography; D004562:Electrocardiography; D017809:Fatal Outcome; D006333:Heart Failure / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D009206:Myocardium / Q000473:pathology*; D013971:Thyrotoxicosis / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D013956:Antithyroid Agents; D002317:Cardiovascular Agents