title: Small RNAs of opposite sign… but same absolute value.
abstract: In ciliates, small RNAs have been shown to target foreign sequences for silencing via elimination from the somatic genome. Fang et al. now reveal a set of Piwi-interacting RNAs (piRNAs) in Oxytricha trifallax that likewise enable genomic self versus nonself discrimination, this time by specifying self sequences for genome retention.
authors.affiliation: Department of Molecular Biosciences, Northwestern University, 2205 Tech Drive, Evanston, IL 60208-3500, USA. erik@northwestern.edu
authors.forename: Erik J
authors.initials: EJ
authors.lastname: Sontheimer