title: Activated PLCγ breaking loose.
abstract: In this issue of Structure, Bunney and colleagues use a combination of NMR, SAXS, crystallography, ITC, and biochemical methods to elucidate, in molecular detail, the sequence of events causing receptor-mediated activation of phospholipase C-γ(1) by protein tyrosine phosphorylation.
authors.affiliation: Institute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany. peter.gierschik@uni-ulm.de
authors.forename: Peter
authors.initials: P
authors.lastname: Gierschik
authors.forename: Anja
authors.initials: A
authors.lastname: Buehler
authors.forename: Claudia
authors.initials: C
authors.lastname: Walliser