title: Modeling the mechanical properties of DNA nanostructures.
abstract: We discuss generalizations of a previously published coarse-grained description [Mergell et al., Phys. Rev. E 68, 021911 (2003)] of double stranded DNA (dsDNA). The model is defined at the base-pair level and includes the electrostatic repulsion between neighbor helices. We show that the model reproduces mechanical and elastic properties of several DNA nanostructures (DNA origamis). We also show that electrostatic interactions are necessary to reproduce atomic force microscopy measurements on planar DNA origamis.
authors.affiliation: CBMN, UMR 5248, CNRS, 2 rue Robert Escarpit, 33600 Pessac, France. jeanmichel.arbona@gmail.com
authors.forename: Jean Michel
authors.initials: JM
authors.lastname: Arbona
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Aimé
authors.forename: Juan
authors.initials: J
authors.lastname: Elezgaray
mesh_terms: D003198:Computer Simulation; D004247:DNA / Q000737:chemistry* / Q000648:ultrastructure*; D055119:Elastic Modulus; D008956:Models, Chemical; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D055672:Static Electricity; D013718:Tensile Strength
chemical_list: D004247:DNA