title: The role of collective motion in examples of coarsening and self-assembly.
abstract: The simplest prescription for building a patterned structure from its constituents is to add particles, one at a time, to an appropriate template. However, self-organizing molecular and colloidal systems in nature can evolve in much more hierarchical ways. Specifically, constituents (or clusters of constituents) may aggregate to form clusters (or clusters of clusters) that serve as building blocks for later stages of assembly. Here we evaluate the character and consequences of such collective motion in a set of prototypical assembly processes. We do so using computer simulations in which a system's capacity for hierarchical dynamics can be controlled systematically. By explicitly allowing or suppressing collective motion, we quantify its effects. We find that coarsening within a two dimensional attractive lattice gas (and an analogous off-lattice model in three dimensions) is naturally dominated by collective motion over a broad range of temperatures and densities. Under such circumstances, cluster mobility inhibits the development of uniform coexisting phases, especially when macroscopic segregation is strongly favored by thermodynamics. By contrast, the assembly of model viral capsids is not frustrated but is instead facilitated by collective moves, which promote the orderly binding of intermediates consisting of several monomers.
authors.affiliation: Systems Biology Centre, University of Warwick, Coventry CV4 7AL, UK ; Department of Chemistry, University of California at Berkeley, Berkeley, CA 94720, USA ; Physical Biosciences and Materials Sciences Divisions, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
authors.forename: Stephen
authors.initials: S
authors.lastname: Whitelam
authors.forename: Edward H
authors.initials: EH
authors.lastname: Feng
authors.forename: Michael F
authors.initials: MF
authors.lastname: Hagan
authors.forename: Phillip L
authors.initials: PL
authors.lastname: Geissler