title: [Ocular toxoplasmosis: from pathophysiology to microbiological diagnosis].
abstract: Toxoplasmosis is the most common cause of posterior uveitis in immunocompetent subjects: 30% of the world population may be affected, with wide variability. However, despite high seroprevalence, the incidence of ocular toxoplasmosis (OT) is limited to about 2% of infected patients; thus, about one million patients in France may be estimated to have active or cicatricial OT. Microbiological tools available to the clinician have considerably advanced over the last two decades, allowing the diagnosis of toxoplasmosis to be confirmed in the vast majority of suspected cases. Regardless of the route of infection (congenital or acquired), laboratory confirmation of OT plays a major role in the patient's management, particularly in atypical cases.
authors.affiliation: Service d'ophtalmologie, hôpitaux universitaires de Strasbourg, nouvel hôpital civil, BP 426, 67091 Strasbourg, France. arnaud.sauer@chru-strasbourg.fr
authors.forename: A
authors.initials: A
authors.lastname: Sauer
authors.forename: O
authors.initials: O
authors.lastname: Villard
authors.forename: T
authors.initials: T
authors.lastname: Bourcier
authors.forename: C
authors.initials: C
authors.lastname: Speeg-Schatz
authors.forename: E
authors.initials: E
authors.lastname: Candolfi
mesh_terms: D000465:Algorithms; D003941:Diagnostic Techniques, Ophthalmological; D006801:Humans; D008828:Microbiological Techniques; D016036:Seroepidemiologic Studies; D014122:Toxoplasma / Q000302:isolation & purification*; D014125:Toxoplasmosis, Congenital / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology