title: [A case of a perivascular epithelioid cell tumor mimicking colon cancer].
abstract: Perivascular epithelioid cell tumor (PEComa) is extremely rare, which originated from mesenchymal cells in the intestine, and composed of histologically and immunohistochemically distinctive perivascular epithelioid cells. We report here on a case of PEComa in the sigmoid colon. A 62-year-old woman presented with hematochzia 10 days ago. Her abdominal computed tomography scan showed a 5 cm sized intraluminal fungating heterogeneously enhanced, high density mass, which infiltrated pericolic tissue surrounding the sigmoid colon. Colonoscopy showed a purple colored polypoid mass with lobulating contour in the sigmoid colon. She underwent laparoscopic anterior resection. On the histologic examination, the tumor consisted of polygonal epithelioid cells with sheet-like growth of nests, which looked like alveolar tissues in lung. The tumor cells were strongly positive stained with human melanoma black-45 (HMB-45). Pathologic examination was compatible with PEComa. Sixteen months after surgery, she did well without tumor recurrence after surgery. We review the literatures concerning PEComa of the intestine focusing on endoscopic findings.
authors.affiliation: Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Young Whan
authors.initials: YW
authors.lastname: Cho
authors.forename: Kyung Jo
authors.initials: KJ
authors.lastname: Kim
authors.forename: Byong Duk
authors.initials: BD
authors.lastname: Ye
authors.forename: Jeong Sik
authors.initials: JS
authors.lastname: Byeon
authors.forename: Seung Jae
authors.initials: SJ
authors.lastname: Myung
authors.forename: Suk Kyun
authors.initials: SK
authors.lastname: Yang
authors.forename: Jin Ho
authors.initials: JH
authors.lastname: Kim
mesh_terms: D003110:Colonic Neoplasms / Q000175:diagnosis; D003113:Colonoscopy; D005260:Female; D006471:Gastrointestinal Hemorrhage; D006801:Humans; D058950:Melanoma-Specific Antigens / Q000378:metabolism; D008875:Middle Aged; D054973:Perivascular Epithelioid Cell Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed; D058951:gp100 Melanoma Antigen
chemical_list: D058950:Melanoma-Specific Antigens; C548637:PMEL protein, human; D058951:gp100 Melanoma Antigen