title: [Different types of 199Tl chloride scintigraphic visualization of malignant tumors of the locomotor apparatus].
abstract: BACKGROUND
  201Tl chloride scintigraphy allows malignant tumors of the locomotor apparatus to be diagnosed. The capacities of scintigraphy with 199Tl chloride, a 201Tl chloride analog, in addition to routine visualization of malignant tumors of the locomotor apparatus, have revealed its untypical variants.
  
  
  OBJECTIVE
  to study the specific features of 199Tl chloride scintigraphic visualization of malignant tumor processes in the locomotor apparatus.
  
  
  METHODS
  199Tl chloride scintigraphy was performed in 85 patients having 107 foci of involvement presented with malignant (n = 57) and benign (n = 50) tumor processes.
  
  
  RESULTS
  Malignant tumors were scintigraphically visualized in 98.1% of cases. Three types of their visualization were identified and studied; these included positive (82.4%) and rare: negative (7.8%), and mixed (9.8%) types associated with the specific features of the histological structure, metabolism, and blood supply of neoplasms and with the pharmacodynamic features of 199Tl chloride. The negative and mixed types, unlike metastatic neoplasms, were highly specific to primary or recurrent malignant tumors.
  
  
  CONCLUSIONS
  Consideration of the negative and mixed types of scintigraphic visualization in addition to routine positive one permitted the sensitivity of diagnosis of malignant locomotor tumors to be increased from 90.4 to 98.1%, without reducing the specificity of 199Tl chloride scintigraphy.
authors.forename: V D
authors.initials: VD
authors.lastname: Zavadovskaia
authors.forename: A P
authors.initials: AP
authors.lastname: Kurazhov
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Kilina
authors.forename: M A
authors.initials: MA
authors.lastname: Zorkal'tsev
authors.forename: E L
authors.initials: EL
authors.lastname: Choĭnzonov
authors.forename: V I
authors.initials: VI
authors.lastname: Chernov
authors.forename: E M
authors.initials: EM
authors.lastname: Slonimskaia
authors.forename: A V
authors.initials: AV
authors.lastname: Bogoutdinova
authors.forename: I I
authors.initials: II
authors.lastname: Anisenia
authors.forename: A A
authors.initials: AA
authors.lastname: Titskaia
authors.forename: R V
authors.initials: RV
authors.lastname: Zel'chan
authors.forename: I G
authors.initials: IG
authors.lastname: Frolova
authors.forename: L S
authors.initials: LS
authors.lastname: Sapunova
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000145:classification / Q000000981:diagnostic imaging* / Q000503:physiopathology; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D002813:Chondrosarcoma / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003947:Diagnostic Techniques, Radioisotope; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013794:Thallium Radioisotopes
chemical_list: D013794:Thallium Radioisotopes