title: Small bowel adenocarcinoma complicating coeliac disease: a report of three cases and the literature review.
abstract: Coeliac disease is associated with an increased risk of malignancy, not only of intestinal lymphoma but also of small intestinal adenocarcinoma which is 82 times more common in patients with celiac disease than in the normal population. We report three additional cases of a small bowel adenocarcinoma in the setting of coeliac disease in order to underline the epidemiological features, clinicopathological findings, and therapeutic approaches of this entity based on a review of the literature. The three patients underwent a surgical treatment followed by adjuvant chemotherapy based on capecitabine/oxaliplatin regimen, and they have well recovered.
authors.affiliation: Department of Medical Oncology, Hassan II University Hospital, Fez, Morocco.
authors.forename: Hafida
authors.initials: H
authors.lastname: Benhammane
authors.forename: Fatima Zahra
authors.initials: FZ
authors.lastname: El M'rabet
authors.forename: Karima
authors.initials: K
authors.lastname: Idrissi Serhouchni
authors.forename: Mounia
authors.initials: M
authors.lastname: El Yousfi
authors.forename: Ilias
authors.initials: I
authors.lastname: Charif
authors.forename: Imane
authors.initials: I
authors.lastname: Toughray
authors.forename: Naoufal
authors.initials: N
authors.lastname: Mellas
authors.forename: Afaf
authors.initials: A
authors.lastname: Riffi Amarti
authors.forename: Khalid
authors.initials: K
authors.lastname: Maazaz
authors.forename: Sidi Adil
authors.initials: SA
authors.lastname: Ibrahimi
authors.forename: Omar
authors.initials: O
authors.lastname: El Mesbahi