title: Commensal bacteria coated by secretory immunoglobulin A and immunoglobulin G in the gastrointestinal tract of pigs and calves.
abstract: A large amount of secretory immunoglobulin A (S-IgA) is secreted in the alimentary tract of mammals. It has been reported that S-IgA coats a portion of commensal intestinal bacteria in human and mouse. However, S-IgA-coated bacteria have not been studied in pigs and calves. In this study, we evaluated the distribution of S-IgA-coated commensal intestinal bacteria in each portion of the gastrointestinal tracts of pigs and calves. Immunoglobulin G (IgG)-coated bacteria were also analyzed because a considerable amount of IgG is secreted in the gastrointestinal tracts of pigs, and in particular, calves. S-IgA- or IgG-coated bacteria were detected in all the segments of the gastrointestinal tracts of pigs and calves. The proportion of S-IgA-coated bacteria to total bacteria (i.e. S-IgA coating ratio) varied in the segments of the gastrointestinal tract in pigs, whereas those of calves were nearly the same throughout the gastrointestinal tract. The S-IgA and IgG coating ratios were higher in pigs than in calves for all segments of the gastrointestinal tract.
authors.affiliation: Department of Bioscience and Chemistry, Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tsuruta
authors.forename: Ryo
authors.initials: R
authors.lastname: Inoue
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Tsukahara
authors.forename: Mitsunori
authors.initials: M
authors.lastname: Nakamoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hara
authors.forename: Kazunari
authors.initials: K
authors.lastname: Ushida
authors.forename: Takaji
authors.initials: T
authors.lastname: Yajima
mesh_terms: D000818:Animals; D001419:Bacteria / Q000276:immunology* / Q000302:isolation & purification*; D002417:Cattle; D005260:Female; D041981:Gastrointestinal Tract / Q000276:immunology* / Q000378:metabolism / Q000382:microbiology*; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000378:metabolism*; D007074:Immunoglobulin G / Q000378:metabolism*; D008297:Male; D051379:Mice; D013552:Swine; D013559:Symbiosis
chemical_list: D007071:Immunoglobulin A, Secretory; D007074:Immunoglobulin G