title: A new boronic acid-based fluorescent sensor for L-dihydroxyphenylalanine.
abstract: Catecholamines, such as dopamine and L-dihydroxyphenylalanine (L-DOPA), are associated with different physiological functions and diseases. In our recent studies, a novel water-soluble boronic acid compound 3c was identified as a selective fluorescent sensor for L-DOPA. This compound not only has the ability to interact with dopamine and catechol, but also has no fluorescence intensity change for L-DOPA precursors in vivo, such as L-tyrosine.
authors.affiliation: Department of Medicinal Chemistry, Shandong University, Ji'nan, China.
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Wu
authors.forename: X Y
authors.initials: XY
authors.lastname: Yang
authors.forename: W F
authors.initials: WF
authors.lastname: Xu
authors.forename: B H
authors.initials: BH
authors.lastname: Wang
authors.forename: H
authors.initials: H
authors.lastname: Fang
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D004295:Dihydroxyphenylalanine / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D001897:Boronic Acids; D002264:Carboxylic Acids; D005456:Fluorescent Dyes; D004295:Dihydroxyphenylalanine