title: Human-to-human transmission of severe fever with thrombocytopenia syndrome bunyavirus through contact with infectious blood.
abstract: We investigated an outbreak of severe fever with thrombocytopenia syndrome (SFTS) that occurred during May and June 2010, to identify the mode of transmission. Contact with the index patient's blood was significantly associated with development of SFTS (P = .01, by the χ(2) test for linear trend); the frequency of contact with the index patient's blood increased the risk of SFTS in a dose-response manner (P = .03, by the χ(2) test for linear trend). We concluded that human-to-human transmission caused this cluster of cases.
authors.affiliation: Center for Disease Control and Prevention of Henan Province, Zhengzhou, Henan Province, China.
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Tang
authors.forename: Weili
authors.initials: W
authors.lastname: Wu
authors.forename: Haifeng
authors.initials: H
authors.lastname: Wang
authors.forename: Yanhua
authors.initials: Y
authors.lastname: Du
authors.forename: Licheng
authors.initials: L
authors.lastname: Liu
authors.forename: Kai
authors.initials: K
authors.lastname: Kang
authors.forename: Xueyong
authors.initials: X
authors.lastname: Huang
authors.forename: Hong
authors.initials: H
authors.lastname: Ma
authors.forename: Feng
authors.initials: F
authors.lastname: Mu
authors.forename: Shiqiang
authors.initials: S
authors.lastname: Zhang
authors.forename: Guohua
authors.initials: G
authors.lastname: Zhao
authors.forename: Ning
authors.initials: N
authors.lastname: Cui
authors.forename: Bao-Ping
authors.initials: BP
authors.lastname: Zhu
authors.forename: Aiguo
authors.initials: A
authors.lastname: You
authors.forename: Haomin
authors.initials: H
authors.lastname: Chen
authors.forename: Guohua
authors.initials: G
authors.lastname: Liu
authors.forename: Weijun
authors.initials: W
authors.lastname: Chen
authors.forename: Bianli
authors.initials: B
authors.lastname: Xu
mesh_terms: D001769:Blood / Q000821:virology*; D002044:Bunyaviridae Infections / Q000635:transmission* / Q000821:virology; D015331:Cohort Studies; D004196:Disease Outbreaks; D018562:Disease Transmission, Infectious; D006801:Humans; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D016856:Phlebovirus / Q000302:isolation & purification*; D012367:RNA, Viral / Q000235:genetics; D012189:Retrospective Studies; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid
chemical_list: D012367:RNA, Viral