title: Point/counterpoint: early-stage Hodgkin lymphoma and the role of radiation therapy.
abstract: The results of recent clinical trials for the management of limited-stage Hodgkin lymphoma have led to considerable debate, especially regarding the role of radiation therapy. This review highlights those recent trials and provides perspectives regarding their interpretation from a radiation oncologist and a hematologist. The trial protocol is available at http://www.nejm.org/doi/suppl/10.1056/NEJMoa1111961/suppl_file/nejmoa1111961_protocol.pdf.
authors.affiliation: 1National Cancer Institute of Canada (NCIC) Clinical Trials Group, Queen’s University, Kingston, ON, Canada.
authors.forename: Ralph M
authors.initials: RM
authors.lastname: Meyer
authors.forename: Richard T
authors.initials: RT
authors.lastname: Hoppe
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000494:pharmacology / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D005260:Female; D020869:Gene Expression Profiling; D006405:Hematology / Q000379:methods; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008495:Medical Oncology / Q000379:methods; D008875:Middle Aged; D011878:Radiotherapy / Q000379:methods*; D016032:Randomized Controlled Trials as Topic; D012306:Risk; D012307:Risk Factors
chemical_list: D000970:Antineoplastic Agents