title: Catalytic highly enantioselective vinylogous Povarov reaction.
abstract: The first example of a catalytic asymmetric vinylogous Povarov reaction is presented. 1-N-Acylamino-1,3-butadienes react selectively at their terminal double bond in the presence of a chiral phosphoric acid catalyst, delivering highly enantioenriched 1,2,3,4-tetrahydroquinolines bearing a synthetically versatile enecarbamate group at the 4-position.
authors.affiliation: Department of Industrial Chemistry Toso Montanari, School of Science, University of Bologna, V. Risorgimento 4, 40136 Bologna, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Caruana
authors.forename: Mariafrancesca
authors.initials: M
authors.lastname: Fochi
authors.forename: Silvia
authors.initials: S
authors.lastname: Ranieri
authors.forename: Andrea
authors.initials: A
authors.lastname: Mazzanti
authors.forename: Luca
authors.initials: L
authors.lastname: Bernardi
mesh_terms: D002070:Butadienes / Q000737:chemistry*; D002384:Catalysis; D010756:Phosphoric Acids / Q000737:chemistry*; D011804:Quinolines / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D002070:Butadienes; D010756:Phosphoric Acids; D011804:Quinolines; C542964:1,2,3,4-tetrahydroquinoline; C030242:phosphoric acid