title: A catalytic asymmetric isatin-involved Povarov reaction: diastereo- and enantioselective construction of spiro[indolin-3,2'-quinoline] scaffold.
abstract: The first catalytic asymmetric isatin-involved Povarov reaction has been established. This method provides an unprecedented approach to access the enantioenriched spiro[indolin-3,2'-quinoline] scaffold with concomitant creation of two quaternary stereogenic centers in high yields and excellent stereoselectivities (all >99:1 dr's, up to 97% ee).
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China. fshi@jsnu.edu.cn
authors.forename: Feng
authors.initials: F
authors.lastname: Shi
authors.forename: Gui-Juan
authors.initials: GJ
authors.lastname: Xing
authors.forename: Ren-Yi
authors.initials: RY
authors.lastname: Zhu
authors.forename: Wei
authors.initials: W
authors.lastname: Tan
authors.forename: Shujiang
authors.initials: S
authors.lastname: Tu