title: Two cases of sepsis-like illness in infants caused by human parechovirus traced back to elder siblings with mild gastroenteritis and respiratory symptoms.
abstract: Sepsis and sepsis-like illness in neonates and infants are serious emergencies. Recently, human parechovirus type 3 (HPeV-3) has been identified as a further etiologic agent of these conditions. We report two unlinked cases of infant HPeV-3 sepsis-like illness whose sources could be traced back to elder siblings with mild gastroenteritis and respiratory symptoms.
authors.affiliation: Institute of Virology, University of Bonn Medical Center, Bonn, Germany. anna-maria.eis-huebinger@ukb.uni-bonn.de
authors.forename: Anna M
authors.initials: AM
authors.lastname: Eis-Hübinger
authors.forename: Isabella
authors.initials: I
authors.lastname: Eckerle
authors.forename: Angelika
authors.initials: A
authors.lastname: Helmer
authors.forename: Ulrike
authors.initials: U
authors.lastname: Reber
authors.forename: Till
authors.initials: T
authors.lastname: Dresbach
authors.forename: Stephan
authors.initials: S
authors.lastname: Buderus
authors.forename: Christian
authors.initials: C
authors.lastname: Drosten
authors.forename: Andreas
authors.initials: A
authors.lastname: Müller
mesh_terms: D002675:Child, Preschool; D005260:Female; D005759:Gastroenteritis / Q000821:virology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008969:Molecular Sequence Data; D030061:Parechovirus; D010850:Picornaviridae Infections / Q000175:diagnosis / Q000635:transmission / Q000821:virology*; D012367:RNA, Viral; D018805:Sepsis / Q000175:diagnosis / Q000635:transmission / Q000821:virology*; D017422:Sequence Analysis, DNA; D035781:Siblings; D019562:Viral Load
chemical_list: D012367:RNA, Viral