title: Characterization of disordered proteins with ENSEMBLE.
abstract: ENSEMBLE is a computational approach for determining a set of conformations that represents the structural ensemble of a disordered protein based on input experimental data. The disordered protein can be an unfolded or intrinsically disordered state. Here, we introduce the latest version of the program, which has been enhanced to facilitate its general release and includes an intuitive user interface, as well as new approaches to treat data and analyse results.
  
  
  METHODS
  ENSEMBLE is a program implemented in C and embedded in a Perl wrapper. It is supported on main Linux distributions. Source codes and installation files, including a detailed example, can be freely downloaded at http://abragam.med.utoronto.ca/∼JFKlab.
authors.affiliation: Molecular Structure & Function Program, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.
authors.forename: Mickaël
authors.initials: M
authors.lastname: Krzeminski
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Marsh
authors.forename: Chris
authors.initials: C
authors.lastname: Neale
authors.forename: Wing-Yiu
authors.initials: WY
authors.lastname: Choy
authors.forename: Julie D
authors.initials: JD
authors.lastname: Forman-Kay
mesh_terms: D000465:Algorithms; D011487:Protein Conformation; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry; D012984:Software
chemical_list: D011506:Proteins