title: [Translational research in geriatrics? A plea based on current biomedical key publications].
abstract: Contemporary geriatric research focuses mainly on observational clinical studies and epidemiological surveys and the translation of basic scientific results from biogerontology into a clinical context is often neglected. Following a definition of translational research the article gives an overview of recent key publications in experimental biogerontology with a special emphasis on their relevance for clinical geriatrics. The topics dealt with include age-induced loss of skeletal muscle (sarcopenia), the aging immune system (immunosenescence) and neurodegenerative disorders (Alzheimer's and Parkinson's disease).
authors.affiliation: Institut für Biomedizin des Alterns, Friedrich-Alexander-Universität Erlangen-Nürnberg, Heimerichstr. 58, 90419, Nürnberg, Deutschland. cornelius.bollheimer@iba.fau.de
authors.forename: L C
authors.initials: LC
authors.lastname: Bollheimer
authors.forename: D
authors.initials: D
authors.lastname: Volkert
authors.forename: T
authors.initials: T
authors.lastname: Bertsch
authors.forename: J
authors.initials: J
authors.lastname: Bauer
authors.forename: J
authors.initials: J
authors.lastname: Klucken
authors.forename: C C
authors.initials: CC
authors.lastname: Sieber
authors.forename: R
authors.initials: R
authors.lastname: Büttner
mesh_terms: D000818:Animals; D003695:Delivery of Health Care / Q000639:trends*; D005853:Geriatrics / Q000639:trends*; D006801:Humans; D057170:Translational Research, Biomedical / Q000639:trends*