title: [Arterial rigidity in patients with chronic obstructive pulmonary disease].
abstract: The aim of this open study was to estimate arterial rigidity in patients with chronic obstructive pulmonary disease (COPD). It included 105 patients above 40 years of age. Exclusion criteria were clinical signs of CHD, peripheral atherosclerosis, and other severe chronic diseases in the exacerbation phase. The control group was comprised of 27 practically healthy volunteers. The arterial fluid was detected using a Tensioclinic arteriograph (Tensiomed, Hungary). Arterial rigidity was estimated in patients of two age groups (below and above 60 years) with COPD of different severity The results suggest the development of arterial wall lesions in proportion to the patients' age and COPD severity. It was shown that excessive arterial rigidity and accelerated pulse wave reflection (increased speed of pulse wave propagation and augmentation index) exert significant influence on the elevation of central arterial pressure. Enhanced rigidity of the arterial wall being a cardiovascular risk factor further prospective studies are needed.
authors.forename: N A
authors.initials: NA
authors.lastname: Karoli
authors.forename: G R
authors.initials: GR
authors.lastname: Dolishniaia
authors.forename: A P
authors.initials: AP
authors.lastname: Rebrov
mesh_terms: D000367:Age Factors; D000368:Aged; D062186:Arterial Pressure; D001158:Arteries / Q000503:physiopathology*; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D019719:Diagnostic Equipment; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D063177:Pulse Wave Analysis / Q000295:instrumentation / Q000379:methods; D015203:Reproducibility of Results; D012307:Risk Factors; D012720:Severity of Illness Index; D014655:Vascular Resistance