title: An improved baseline model for a human arterial network to study the impact of aneurysms on pressure-flow waveforms.
abstract: In this study, an improved and robust one-dimensional human arterial network model is presented. The one-dimensional blood flow equations are solved using the Taylor-locally conservative Galerkin finite element method. The model improvements are carried out by adopting parts of the physical models from different authors to establish an accurate baseline model. The predicted pressure-flow waveforms at various monitoring positions are compared against in vivo measurements from published works. The results obtained show that wave shapes predicted are similar to that of the experimental data and exhibit a good overall agreement with measured waveforms. Finally, computational studies on the influence of an abdominal aortic aneurysm are presented. The presence of aneurysms results in a significant change in the waveforms throughout the network.
authors.affiliation: Swansea Biomedical Computing Lab, College of Engineering, Swansea University, Swansea SA2 8PP, UK.
authors.forename: K
authors.initials: K
authors.lastname: Low
authors.forename: R
authors.initials: R
authors.lastname: van Loon
authors.forename: I
authors.initials: I
authors.lastname: Sazonov
authors.forename: R L T
authors.initials: RL
authors.lastname: Bevan
authors.forename: P
authors.initials: P
authors.lastname: Nithiarasu
mesh_terms: D000328:Adult; D017544:Aortic Aneurysm, Abdominal / Q000473:pathology / Q000503:physiopathology; D001158:Arteries / Q000033:anatomy & histology* / Q000502:physiology*; D020342:Finite Element Analysis; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008955:Models, Cardiovascular