title: Extranodal follicular lymphoma in the lung of a free-ranging red deer (Cervus elaphus).
abstract: A hunted free-ranging female red deer (Cervus elaphus) from a region near the Nahuel Huapi National Park, Northern Patagonia, Argentina, had a focally extensive peribronchial lymphoid proliferative lesion in the lung characterized by formation of multiple follicles, with prominent germinal centers lacking mantle zone cells and antigen-related polarity. On examination of immunohistochemically stained tissues, a predominance of B cells (cluster of differentiation [CD]20 positive) with only a few scattered T cells (CD3 positive) were present. The histologic and immunohistochemical characteristics are consistent with follicular lymphoma, which is frequently seen in human beings and less frequently in domestic animals.
authors.affiliation: Institute of Pathology, Faculty of Veterinary Sciences, National University of La Plata, La Plata, Argentina.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Chang Reissig
authors.forename: Victor E
authors.initials: VE
authors.lastname: Valli
authors.forename: Patricia
authors.initials: P
authors.lastname: Pesavento
authors.forename: Adriana R
authors.initials: AR
authors.lastname: Massone
authors.forename: Beatriz
authors.initials: B
authors.lastname: Iovanitti
authors.forename: Eduardo J
authors.initials: EJ
authors.lastname: Gimeno
authors.forename: Francisco A
authors.initials: FA
authors.lastname: Uzal
mesh_terms: D000818:Animals; D018951:Antigens, CD20 / Q000302:isolation & purification; D001118:Argentina; D001402:B-Lymphocytes / Q000473:pathology; D017252:CD3 Complex / Q000302:isolation & purification; D003670:Deer; D017809:Fatal Outcome; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary; D008175:Lung Neoplasms / Q000473:pathology / Q000662:veterinary*; D008224:Lymphoma, Follicular / Q000473:pathology / Q000662:veterinary*; D013601:T-Lymphocytes / Q000473:pathology
chemical_list: D018951:Antigens, CD20; D017252:CD3 Complex