title: N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation.
abstract: Metabolic chemical reporters of glycosylation allow for the visualization and identification of a variety of glycoconjugates by taking advantage of the promiscuity of carbohydrate metabolism. Here we describe the synthesis and characterization of metabolic chemical reporters bearing an N-propargyloxycarbamate (Poc) group that creates discrimination between glycosylation pathways.
authors.affiliation: Department of Chemistry, University of Southern California, Los Angeles, USA.
authors.forename: Leslie A
authors.initials: LA
authors.lastname: Bateman
authors.forename: Balyn W
authors.initials: BW
authors.lastname: Zaro
authors.forename: Kelly N
authors.initials: KN
authors.lastname: Chuh
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Pratt
mesh_terms: D000117:Acetylglucosamine / Q000737:chemistry; D000818:Animals; D002219:Carbamates / Q000737:chemistry* / Q000378:metabolism; D057930:Click Chemistry; D006031:Glycosylation; D051379:Mice; D009005:Monosaccharides / Q000737:chemistry*; D041681:NIH 3T3 Cells; D012235:Rhodamines / Q000737:chemistry
chemical_list: D002219:Carbamates; D009005:Monosaccharides; D012235:Rhodamines; D000117:Acetylglucosamine