title: Meningitis complicated by subdural empyema and deafness caused by pneumoccoccal serotype 7F in a 17-month-old child: a case report.
abstract: Despite the availability of effective antibacterial agents and vaccines, pneumococcal meningitis and sepsis are still associated with high mortality rates and a high risk of neurological sequelae. We describe the case of a 17-month-old boy vaccinated with heptavalent pneumococcal conjugate vaccine (PCV7) who developed bacterial meningitis complicated by subdural empyema and deafness caused by Streptococcus pneumoniae serotype 7F. The 7F strain is not contained in PCV7 (the only vaccine on the market at the time of the onset of meningitis) but is included in the new pediatric 13-valent PCV, which may therefore prevent cases such as this in the future.
authors.affiliation: Pediatric Clinic 1, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Bosis
authors.forename: M
authors.initials: M
authors.lastname: Semino
authors.forename: I
authors.initials: I
authors.lastname: Picciolli
authors.forename: R
authors.initials: R
authors.lastname: Pinzani
authors.forename: L
authors.initials: L
authors.lastname: Genitori
authors.forename: N
authors.initials: N
authors.lastname: Principi
authors.forename: S
authors.initials: S
authors.lastname: Esposito
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003638:Deafness / Q000209:etiology*; D013354:Empyema, Subdural / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology / Q000601:surgery; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008586:Meningitis, Pneumococcal / Q000150:complications* / Q000188:drug therapy / Q000276:immunology* / Q000601:surgery; D022242:Pneumococcal Vaccines / Q000276:immunology*; D016133:Polymerase Chain Reaction; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D022242:Pneumococcal Vaccines