title: Effect of low central venous pressure on postoperative pulmonary complications in patients undergoing liver transplantation.
abstract: OBJECTIVE
  To investigate the effect of the low central venous pressure (LCVP) technique on postoperative pulmonary complications in patients undergoing liver transplantation.
  
  
  METHODS
  Sixty-five adult patients were randomly divided into a LCVP group (n = 33) and a control group (n = 32). The CVP was maintained below 5 mmHg or 40 % lower than baseline in the LCVP group, by manipulating the patient's posture, limiting infusion volume, and administration of nitroglycerine. Recipients in the control group received standard care. The volume of intraoperative blood loss and transfusion, and postoperative pulmonary complications of the two groups were compared.
  
  
  RESULTS
  The LCVP group had a significantly earlier tracheal extubation (33 ± 33 vs. 53 ± 36 h, P < 0.05), and lower rate of postoperative pulmonary complications (42.8 vs. 71.4 %, P < 0.05) in comparison to the control group. The most frequent complication was pleural effusion (28.5 vs. 67.8 %, P < 0.05), followed by pneumonia (24.2 vs. 57.1 %, P < 0.05) and pulmonary edema (3.1 vs. 14.3 %, P < 0.05).
  
  
  CONCLUSIONS
  The LCVP technique during liver transplantation could decrease postoperative pulmonary complications.
authors.affiliation: Department of Anesthesiology, The Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong County, Chongqing, 400016, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
authors.forename: Hua-kai
authors.initials: HK
authors.lastname: He
authors.forename: Bo
authors.initials: B
authors.lastname: Cheng
authors.forename: Ke
authors.initials: K
authors.lastname: Wei
authors.forename: Su
authors.initials: S
authors.lastname: Min
mesh_terms: D000328:Adult; D016063:Blood Loss, Surgical / Q000517:prevention & control; D001803:Blood Transfusion / Q000706:statistics & numerical data; D002496:Central Venous Pressure / Q000502:physiology*; D005260:Female; D006801:Humans; D007430:Intraoperative Care / Q000379:methods*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D005996:Nitroglycerin / Q000008:administration & dosage; D010996:Pleural Effusion / Q000517:prevention & control*; D011014:Pneumonia / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control*; D011187:Posture / Q000502:physiology; D011654:Pulmonary Edema / Q000517:prevention & control
chemical_list: D005996:Nitroglycerin