title: Langerhans cell histiocytosis: a multisystem disorder.
abstract: Langerhans cell histiocytosis can involve single or multiple organ/tissue systems and may go undiagnosed for years until it enters the clinician's differential diagnosis framework. We report on a young patient who initially presented with diabetes insipidus and subsequently with pyrexia of unknown origin. She progressed from single system Langerhans cell histiocytosis to multisystem involvement and remains in long-term remission following chemotherapy.
authors.affiliation: Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK. atif113_2000@yahoo.co.uk
authors.forename: A
authors.initials: A
authors.lastname: Munir
authors.forename: N
authors.initials: N
authors.lastname: Leech
authors.forename: K P
authors.initials: KP
authors.lastname: Windebank
authors.forename: J
authors.initials: J
authors.lastname: McLelland
authors.forename: G L
authors.initials: GL
authors.lastname: Jones
authors.forename: D
authors.initials: D
authors.lastname: Mitra
authors.forename: A
authors.initials: A
authors.lastname: Jenkins
authors.forename: R
authors.initials: R
authors.lastname: Quinton
mesh_terms: D000328:Adult; D003919:Diabetes Insipidus / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D005334:Fever / Q000175:diagnosis; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D055815:Young Adult