title: Identifying people at a high risk of developing pancreatic cancer.
abstract: Pancreatic cancer is a leading cause of cancer death, and it has the poorest prognosis of any major tumour type. Familial pancreatic cancer registries are important for investigating the genetic aetiology of this devastating disease. Using data from our familial pancreatic cancer registry and other registries, this Review discusses the usefulness of family registries in the study of pancreatic and other cancers, and also how such registries provide a unique opportunity for laboratory, population and clinical research.
authors.affiliation: Department of Oncology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins School of Medicine, Baltimore, Maryland 21231, USA. aklein1@jhmi.edu
authors.forename: Alison P
authors.initials: AP
authors.lastname: Klein
mesh_terms: D002277:Carcinoma / Q000175:diagnosis* / Q000209:etiology*; D020022:Genetic Predisposition to Disease; D006801:Humans; D009386:Neoplastic Syndromes, Hereditary / Q000175:diagnosis* / Q000209:etiology*; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000209:etiology*; D010375:Pedigree; D012042:Registries; D018570:Risk Assessment