title: Squamous cell carcinoma in mature cystic teratoma of the ovary.
abstract: BACKGROUND
  Malignant transformation is a rare complication of mature cystic teratoma, with squamous cell carcinoma as the most common malignancy (in 75% of cases). In this article we present a case of a well-differentiated squamous cell carcinoma arising in a mature cystic teratoma and discuss the morphological and clinico-pathological features of malignant transformation in teratoma.
  
  
  METHODS
  An 80-year-old woman with symptoms of acute abdomen underwent left salpingo-oophorectomy. Gross examination showed a cystic mass measuring 20 cm in diameter, with papillary formation on its internal surface. Histology revealed a well-differentiated squamous cell carcinoma arising in mature cystic teratoma. Squamous epithelium surrounding the tumor was dysplastic.
  
  
  CONCLUSIONS
  Squamous cell carcinoma in mature cystic teratoma is a rare pathologic event and in most cases it is an accidental pathohistological finding.
authors.affiliation: Center for Pathology and Histology, Clinical Center of Vojvodina, Novi Sad. jelena.amidzic@gmail.com
authors.forename: Jelena
authors.initials: J
authors.lastname: Amidzić
authors.forename: Matilda
authors.initials: M
authors.lastname: Dolai
authors.forename: Mihaela Mocko
authors.initials: MM
authors.lastname: Kaćanski
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Gluhović
authors.forename: Jelena
authors.initials: J
authors.lastname: Ilić
authors.forename: Snezana
authors.initials: S
authors.lastname: Bozanić
mesh_terms: D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*; D013724:Teratoma / Q000473:pathology*