title: [Safety update on vaccination during pregnancy].
abstract: During influenza A pandemia, the vaccination on pregnant women has raised many questions. Pandemia, easiness of travelling, and insufficient vaccinal coverage, expose these patients to infection which may have serious consequences on their pregnancy and on the child to born. On pregnant women, the precautionary principle is a priority and the evaluation of epidemiological risk is essential, in order to prevent adverses events. Prophylactic vaccinal administration against infections should be assessed with caution due to the little amount of available data. Its use will depend on the vaccine's composition and known side effects, the stage of pregnancy, as well as the benefit for the mother and the child to born, and her clinical history. Whatever the vaccine's nature, its administration never justifies a therapeutic abortion; its evolution must be closely followed to cover the occurrence of complication.
authors.affiliation: Centre Régional de Pharmacovigilance, Centre Hospitalier Universitaire de Besançon, Besançon, France. mmoltenis@chu-besancon.fr
authors.forename: Mélanie
authors.initials: M
authors.lastname: Moltenis
authors.forename: Marie-Blanche
authors.initials: MB
authors.lastname: Valnet-Rabier
authors.forename: Joël
authors.initials: J
authors.lastname: Leroy
authors.forename: Jean-Pierre
authors.initials: JP
authors.lastname: Kantelip
mesh_terms: D000075202:Contraindications; D005260:Female; D006801:Humans; D008589:Meningococcal Infections / Q000453:epidemiology / Q000517:prevention & control; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000517:prevention & control*; D011818:Rabies / Q000453:epidemiology / Q000517:prevention & control; D014195:Travel / Q000706:statistics & numerical data; D014376:Tuberculosis / Q000453:epidemiology / Q000517:prevention & control; D014611:Vaccination / Q000009:adverse effects* / Q000706:statistics & numerical data