title: A new antibacterial phenanthrenequinone from Dendrobium sinense.
abstract: A new phenanthrenequinone, named denbinobin B (1), together with three known phenanthrenes was isolated from the whole plant of Dendrobium sinense T. Tang et F.T. Wang, an endemic and endangered orchid to Hainan Island. The new compound was elucidated using a combination of 1D, 2D NMR (COSY, HMQC, and HMBC) techniques, and HR-ESI-MS analyses. Compound 1 exhibited moderate antibacterial activity against Staphylococcus aureus with the diameter of the inhibition zone of 16.5 mm.
authors.affiliation: Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
authors.forename: Xiu-Juan
authors.initials: XJ
authors.lastname: Chen
authors.forename: Wen-Li
authors.initials: WL
authors.lastname: Mei
authors.forename: Wen-Jian
authors.initials: WJ
authors.lastname: Zuo
authors.forename: Yan-Bo
authors.initials: YB
authors.lastname: Zeng
authors.forename: Zhi-Kai
authors.initials: ZK
authors.lastname: Guo
authors.forename: Xi-Qiang
authors.initials: XQ
authors.lastname: Song
authors.forename: Hao-Fu
authors.initials: HF
authors.lastname: Dai
mesh_terms: D000880:Anthraquinones; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002681:China; D031667:Dendrobium / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular; D010616:Phenanthrenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000880:Anthraquinones; D000900:Anti-Bacterial Agents; D010616:Phenanthrenes; C436544:denbinobin; C579380:denbinobin B