title: [Should subclinical hypothyroidism in older persons be treated?].
abstract: Subclinical hypothyroidism is a common finding in older persons. Clinical guidelines are inconsistent in providing recommendations for the treatment of subclinical hypothyroidism, especially in older persons. To date, there is no high-quality evidence from randomized controlled trials about the effects of treatment of subclinical hypothyroidism in older persons. Any definitive recommendations on treatment should be based on data from large randomized placebo-controlled trials.
authors.affiliation: Leids Universitair Medisch Centrum, afd. Public Health en Eerstelijnsgeneeskunde, Leiden, the Netherlands.
authors.forename: Wendy P J
authors.initials: WP
authors.lastname: den Elzen
authors.forename: Jan W A
authors.initials: JW
authors.lastname: Smit
authors.forename: Simon P
authors.initials: SP
authors.lastname: Mooijaart
authors.forename: Jacobijn
authors.initials: J
authors.lastname: Gussekloo
mesh_terms: D000375:Aging / Q000473:pathology*; D019317:Evidence-Based Medicine; D006801:Humans; D007037:Hypothyroidism / Q000628:therapy*; D017410:Practice Guidelines as Topic; D016032:Randomized Controlled Trials as Topic; D013963:Thyroid Hormones / Q000627:therapeutic use
chemical_list: D013963:Thyroid Hormones