title: Nuclear transport: beginning to gel?
abstract: The massive nuclear pore complex mediates nucleocytoplasmic traffic ranging from a single histone to a viral genome. To date, dissecting mechanism has been more an exercise in prediction than biochemical certainty. A recent study combines recombinant proteins with nuclei reconstituted in vitro to test predictions in a startlingly productive manner.
authors.affiliation: Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA. mpowers@emory.edu
authors.forename: Maureen A
authors.initials: MA
authors.lastname: Powers
authors.forename: Douglass J
authors.initials: DJ
authors.lastname: Forbes
mesh_terms: D021581:Active Transport, Cell Nucleus; D000818:Animals; D006801:Humans; D022022:Nuclear Pore / Q000378:metabolism*; D028861:Nuclear Pore Complex Proteins / Q000378:metabolism*
chemical_list: D028861:Nuclear Pore Complex Proteins