title: Comparison of lower urinary tract symptoms between women with detrusor overactivity and impaired contractility, and detrusor overactivity and preserved contractility.
abstract: OBJECTIVE
  We compared symptoms in women with detrusor overactivity with impaired contractility and women with detrusor overactivity who had preserved contractility.
  
  
  METHODS
  The study included 359 consecutive women with detrusor overactivity who underwent multichannel urodynamics at our department between 2009 and 2011. The women were divided into 2 groups, including 151 (42%) with detrusor overactivity and impaired contractility, and 208 (58%) with detrusor overactivity and preserved contractility. We compared the 2 groups.
  
  
  RESULTS
  Women with detrusor overactivity and impaired contractility were older (mean ± SD age 73.2 ± 17.3 vs 54.1 ± 20.7 years) with a higher frequency of diabetes mellitus (49% vs 31%, each p <0.001). The prevalence of previous urinary retention and recurrent cystitis was significantly higher in women with impaired contractility (7% vs 1%, p <0.01 and 22% vs 7%, p <0.001, respectively). Mean post-void residual urine was greater in the group with impaired contractility (89 ± 42 vs 21 ± 18 ml) and the mean maximal flow rate was lower (11 ± 6 vs 23 ± 5 ml per second, each p <0.001). The frequency of storage symptoms was similar in the 2 groups. However, voiding symptoms were more common in women with impaired contractility, including a slow stream in 69% vs 42%, an intermittent stream in 72% vs 26%, hesitancy in 35% vs 22%, straining in 84% vs 26%, terminal dribbling in 73% vs 42% and incomplete emptying in 71% vs 49% (p <0.001).
  
  
  CONCLUSIONS
  Women with detrusor overactivity and impaired contractility are older than women with detrusor overactivity and preserved detrusor contractility. Urinary retention and recurrent cystitis are more frequent in women with detrusor overactivity and impaired contractility, and voiding symptoms are significantly more common.
authors.affiliation: Department of Urology, Assaf Harofeh Medical Center, Zerifin and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. stavkobi@gmail.com
authors.forename: Kobi
authors.initials: K
authors.lastname: Stav
authors.forename: Yaniv
authors.initials: Y
authors.lastname: Shilo
authors.forename: Amnon
authors.initials: A
authors.lastname: Zisman
authors.forename: Arie
authors.initials: A
authors.lastname: Lindner
authors.forename: Dan
authors.initials: D
authors.lastname: Leibovici
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D005260:Female; D006801:Humans; D059411:Lower Urinary Tract Symptoms; D008875:Middle Aged; D009119:Muscle Contraction / Q000502:physiology*; D015995:Prevalence; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment; D001743:Urinary Bladder / Q000502:physiology*; D053201:Urinary Bladder, Overactive / Q000175:diagnosis* / Q000453:epidemiology*; D014549:Urinary Incontinence / Q000175:diagnosis / Q000453:epidemiology; D016055:Urinary Retention / Q000175:diagnosis / Q000453:epidemiology; D014555:Urination Disorders / Q000175:diagnosis / Q000453:epidemiology*; D014563:Urodynamics