title: NICE guideline: management of venous thromboembolic diseases and role of thrombophilia testing.
abstract: The National Institute for Health and Clinical Excellence recently published a clinical guideline on the management of venous thromboembolic disease and thrombophilia testing. Several stand-out recommendations are made which may be practice changing for many physicians, such as catheter-directed thrombolysis for ilio-femoral deep venous thrombosis, routine cancer screening and extended duration of anticoagulation for unprovoked events. In this article, we summarise the key points of the guideline and discuss remaining areas of controversy.
authors.affiliation: National Pulmonary Hypertension Service, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK. l.howard@imperial.ac.uk
authors.forename: Luke S
authors.initials: LS
authors.lastname: Howard
authors.forename: Rodney J
authors.initials: RJ
authors.lastname: Hughes
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D006801:Humans; D009369:Neoplasms / Q000453:epidemiology; D017410:Practice Guidelines as Topic; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000188:drug therapy; D015912:Thrombolytic Therapy; D019851:Thrombophilia / Q000150:complications*; D054556:Venous Thromboembolism / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*
chemical_list: D000925:Anticoagulants