title: The function of ABCB transporters in auxin transport.
abstract: Plant ATP-binding cassette (ABC) transporters consist of largest family members among many other membrane transporters and have been implicated in various functions such as detoxification, disease resistance and transport of diverse substrates. Of the ABC-B/multi-drug resistance/P-glycoprotein (ABCB/MDR/PGP) subfamily, at least five members have been reported to mediate cellular transport of auxin or auxin derivatives. Although single mutant phenotypes of these genes are milder than PIN-FORMED (PIN) mutants, those ABCBs significantly contribute for the directional auxin movement in the tissue-level auxin-transporting assay. Uniformly localized ABCB proteins in the plasma membrane (PM) are generaly found in different plant species and stably retained regardless of internal and external signals. This implies that these ABCB proteins may play as basal auxin transporters.
authors.affiliation: College of Biological Sciences and Biotechnology; Chungnam National University; Daejeon, Korea.
authors.forename: Misuk
authors.initials: M
authors.lastname: Cho
authors.affiliation: Department of Biological Sciences and Plant Genomics and Breeding Institute; Seoul National University; Seoul, Korea.
authors.forename: Hyung-Taeg
authors.initials: HT
authors.lastname: Cho
mesh_terms: D017360:Arabidopsis / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D001692:Biological Transport / Q000502:physiology; D018506:Gene Expression Regulation, Plant; D007210:Indoleacetic Acids / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; D007210:Indoleacetic Acids