title: Use of dermal-fat grafts in the post-oncological reconstructive surgery of atrophies in the zygomatic region: clinical evaluations in the patients undergone to previous radiation therapy.
abstract: BACKGROUND
  Grafting of autologous adipose tissue can be recommended in some cases of facial plastic surgery. Rhabdomyosarcoma is a type of cancer that can also affect the orbit. Enucleation of the eye can cause atrophy of the corresponding hemiface and decreased orbital growth.
  
  
  METHODS
  We report a case of a female patient with a medical history of surgical enucleation of the right eyeball, who had received rhabdomyosarcoma radiation therapy in her youth. The patient presented with a depression in the right zygomatic region. We took a dermal-fat flap from the abdominal region, which had been previously treated.
  
  
  RESULTS
  The surgical outcome, 48 hours, and much clearly 31 days after the surgery, revealed that the right zygomatic region had returned to its proper anatomical shape, although there were still signs of postoperative edema.
  
  
  CONCLUSIONS
  Very damaged tissues, like those exposed to radiation therapy, are generally not suitable for grafting of adipose tissue.
  
  
  CONCLUSIONS
  In the described case, we achieved a technically and aesthetically satisfying result despite the patient's medical history involving several perplexities about the use of autologous dermal-fat tissues, because of prior radiation therapy exposure. The clinical case shows that even a region exposed to radiation therapy can be a valid receiving bed for dermal-fat grafting.
authors.affiliation: Department of Dental Sciences and Surgery, University of Bari, Bari, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Inchingolo
authors.forename: Marco
authors.initials: M
authors.lastname: Tatullo
authors.forename: Andrea
authors.initials: A
authors.lastname: Pacifici
authors.forename: Marco
authors.initials: M
authors.lastname: Gargari
authors.forename: Alessio D
authors.initials: AD
authors.lastname: Inchingolo
authors.forename: Angelo M
authors.initials: AM
authors.lastname: Inchingolo
authors.forename: Gianna
authors.initials: G
authors.lastname: Dipalma
authors.forename: Massimo
authors.initials: M
authors.lastname: Marrelli
authors.forename: Fabio M
authors.initials: FM
authors.lastname: Abenavoli
authors.forename: Luciano
authors.initials: L
authors.lastname: Pacifici
mesh_terms: D000328:Adult; D001284:Atrophy / Q000209:etiology / Q000601:surgery; D019882:Blepharoplasty / Q000379:methods; D004954:Esthetics; D015353:Eye Enucleation / Q000009:adverse effects* / Q000379:methods; D005134:Eye Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D018714:Radiotherapy, Adjuvant; D019651:Plastic Surgery Procedures / Q000379:methods*; D012208:Rhabdomyosarcoma / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D018570:Risk Assessment; D050151:Subcutaneous Fat / Q000637:transplantation*; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D015050:Zygoma / Q000503:physiopathology / Q000601:surgery*