title: Hello out there...is anybody listening?
abstract: Using a murine xenograft model system, Kuznetsov and colleagues show the existence of systemic interactions between a primary tumor and the growth of distal tumors in both homotypic and heterotypic tissues. Importantly, they show that the characteristics of the primary tumor govern the histologic features of the distal tumor through distinct pathways, thus providing novel opportunities for risk assessment, prognosis, prevention, and intervention.
authors.affiliation: Department of Pathology and 2Comprehensive Cancer Center, University of California San Francisco, San Francisco, California 94143, USA.
authors.forename: Rosa Anna
authors.initials: RA
authors.lastname: DeFilippis
authors.forename: Thea D
authors.initials: TD
authors.lastname: Tlsty
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000473:pathology*; D001854:Bone Marrow Cells / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans