title: [Solanum torvum, toxicological evaluation on microorganisms and sperm cells].
abstract: OBJECTIVE
  to evaluate the toxic effect of an aqueous extract of Solanum torvum on microorganisms responsible for genitourinary infections as well as the adverse effects on sperm cells.
  
  
  METHODS
  it was determined the microbial toxicity of a freeze-dried aqueous extract (obtained from the leaves and stems of Solanum torvum), against wild strains of Escherichia coli, Neisseria gonorrhoeae and Candida albicans, using the test of poisoning in culture medium at concentrations of 50, 100 and 200 mg/mL. The response-was evaluated with the colony diameter (mm). Then, it was evaluated the toxicological potential on male reproductive system using the testing of morphology of the sperm head in NMRI mice.
  
  
  RESULTS
  the Solanum torvum had bacteriostatic antibacterial activity. There were not observed alterations in quantity and quality characteristics in semen with the oral and doses used of 500, 1000 and 2000 mg/kg of weight.
  
  
  CONCLUSIONS
  the Solanum torvum described, inhibits the growth of bacteria and produces no disturbance on semen quality in the species studied.
authors.affiliation: Centro de Biofísica Médica, Universidad de Oriente, Laboratorio de Genética Toxicológica, Santiago de Cuba, Cuba. anibalodio@yahoo.com.
authors.forename: Aníbal
authors.initials: A
authors.lastname: Domínguez-Odio
authors.forename: Edgar
authors.initials: E
authors.lastname: Puente-Zapata
authors.forename: Irela Yolaine
authors.initials: IY
authors.lastname: Pérez-Andrés
authors.forename: Hilario
authors.initials: H
authors.lastname: Salas-Pérez
mesh_terms: D000818:Animals; D002176:Candida albicans / Q000187:drug effects*; D004926:Escherichia coli / Q000187:drug effects*; D006801:Humans; D008297:Male; D051379:Mice; D009344:Neisseria gonorrhoeae / Q000187:drug effects*; D010936:Plant Extracts / Q000633:toxicity*; D032322:Solanum; D013094:Spermatozoa / Q000187:drug effects*
chemical_list: D010936:Plant Extracts