title: Effects of post biopsy digital rectal compression on improving prostate cancer staging using magnetic resonance imaging in localized prostate cancer.
abstract: OBJECTIVE
  To evaluate the effectiveness of digital rectal-compression immediately after transrectal prostate biopsy (P-bx) for improving the accuracy of prostate cancer (PCa) staging.
  
  
  METHODS
  Between July 2008 and June 2010, 94 consecutive patients who had a radical prostatectomy were included in our retrospective analysis. The exclusion criteria included a history of previous P-bx and surgery, a biopsy performed in another hospital, a number of biopsy cores different from 12, or a condition interfering with bleeding assessment. The subjects were divided into two groups, compression and non-compression. All enrolled patients took magnetic resonance imaging (MRI) for PCa staging.
  
  
  RESULTS
  The compression and non-compression groups were comparable with respect to several baseline characteristics. However, the total hemorrhage score of intraprostatic bleeding was significantly different between the groups, even with adjustment for the time from biopsy to MRI (compression:15.4 ± 2.32, non-compression: 24.9 ± 2.43, p<0.001). The intra-prostatic cancer location matching rate was higher in the compression group (78.0%) than in the non-compression group (70.2%) (p = 0.011). Overall accuracy of staging in compression and non-compression groups was 84.7% and 77.3%, respectively.
  
  
  CONCLUSIONS
  Our results demonstrate that digital rectal compression performed immediately after prostate biopsy to reduce intraprostatic hemorrhage improves the accuracy for detection of PCa using MRI.
authors.affiliation: Department of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, Yongin, Korea.
authors.forename: Kyung Kgi
authors.initials: KK
authors.lastname: Park
authors.forename: Mun Su
authors.initials: MS
authors.lastname: Chung
authors.forename: Soo Yoon
authors.initials: SY
authors.lastname: Chung
authors.forename: Joo Hee
authors.initials: JH
authors.lastname: Kim
authors.forename: Byung Ha
authors.initials: BH
authors.lastname: Chung
mesh_terms: D000368:Aged; D001706:Biopsy; D001707:Biopsy, Needle; D051517:Digital Rectal Examination; D006470:Hemorrhage / Q000517:prevention & control; D006487:Hemostasis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods*; D011312:Pressure; D011467:Prostate / Q000473:pathology; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D015203:Reproducibility of Results; D012189:Retrospective Studies