title: Hydroxyl octadecenoic acids biosynthesized by crown galls of Panax quinquefolium induced by artermisinic acid.
abstract: OBJECTIVE
  To investigate the effect of artermisinic acid on the secondary metabolites production of Panax quinquefolium crown galls.
  
  
  METHODS
  Artemisinic acid was added into the suspended cells of Panax quinquefolium crown galls and co-culture for two days. Products were isolated with chromatographic method.
  
  
  RESULTS
  Three hydroxyl octadecenoic acids [9,12,13-trihydroxy-10-octadecenoic acid (1), 11,12,13-trihydroxy-9-octadecenoic acid (2) and 11-hydroxy-12,13-epoxy-9-octadecenoic acid (3)] were isolated from crown galls of Panax quinquefolium.
  
  
  CONCLUSIONS
  Artermisinic acid as one of the new type of phytohormones that might induce the production of 13-lipoxygenases in crown galls of Panax quinquefolium.
authors.affiliation: College of Pharmacy, Jinan University, Guangzhou 510632, China.
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Zhu
authors.forename: Wei
authors.initials: W
authors.lastname: Wen
authors.forename: Yan-Shan
authors.initials: YS
authors.lastname: Hu
authors.forename: Yu
authors.initials: Y
authors.lastname: Tang
authors.forename: Rong-Min
authors.initials: RM
authors.lastname: Yu
mesh_terms: D037621:Artemisinins / Q000494:pharmacology*; D002478:Cells, Cultured; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D003470:Culture Media; D005227:Fatty Acids / Q000096:biosynthesis* / Q000737:chemistry / Q000302:isolation & purification; D006880:Hydroxy Acids / Q000737:chemistry / Q000302:isolation & purification; D009829:Oleic Acids / Q000096:biosynthesis / Q000737:chemistry / Q000302:isolation & purification; D005894:Panax / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D018517:Plant Roots / Q000378:metabolism; D030821:Plants, Genetically Modified; D010946:Plants, Medicinal / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D046509:Tissue Culture Techniques / Q000379:methods
chemical_list: D037621:Artemisinins; D003470:Culture Media; D005227:Fatty Acids; D006880:Hydroxy Acids; D009829:Oleic Acids; C059227:9,12,13-trihydroxy-10-octadecenoic acid; C047721:artemisic acid