title: Toxic effects of acetochlor on mortality, reproduction and growth of Caenorhabditis elegans and Pristionchus pacificus.
abstract: The effects of acetochlor on the mortality, growth and reproduction of two nematode species were assessed. The LC50 values for Caenorhabditis elegans and Pristionchus pacificus were 1,296 and 210.7 mg/L at 24 h, and 540.0 and 126.4 mg/L at 48 h exposure, respectively. In three succession generations, reproductive capacity was more sensitive in P. pacificus than in C. elegans. Moreover, the sublethal test endpoint of final length was more sensitive with P. pacificus. This study suggested that acetochlor had no long-term effects on C. elegans at lower concentrations. The higher concentrations of acetochlor (from 40 to 160 mg/L) revealed sublethal toxicity to the two tested species, with P. pacificus being more sensitive than C. elegans.
authors.affiliation: State Key Laboratory of Forest and Soil Ecology, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang, 110164, China.
authors.forename: Jingnan
authors.initials: J
authors.lastname: Zhang
authors.forename: Wenju
authors.initials: W
authors.lastname: Liang
authors.forename: Xia
authors.initials: X
authors.lastname: Wu
authors.forename: Siwei
authors.initials: S
authors.lastname: Jiang
authors.forename: Qi
authors.initials: Q
authors.lastname: Li
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D017173:Caenorhabditis elegans / Q000187:drug effects* / Q000254:growth & development*; D004784:Environmental Monitoring; D007928:Lethal Dose 50; D009348:Nematoda / Q000187:drug effects / Q000254:growth & development; D012098:Reproduction / Q000187:drug effects; D012989:Soil Pollutants / Q000633:toxicity*; D013045:Species Specificity; D016019:Survival Analysis; D014052:Toluidines / Q000633:toxicity*
chemical_list: D012989:Soil Pollutants; D014052:Toluidines; C043377:acetochlor