title: Stealth attack: plaque-specific antibody allows for efficient Aβ removal without side effects.
abstract: Anti-Aβ antibodies are being developed as potential treatments for Alzheimer's disease. Some have dose-limiting side effects and many do not robustly remove pre-existing amyloid plaques. In this issue of Neuron, DeMattos et al. (2012) demonstrate that an amyloid plaque-specific antibody removes existing Aβ aggregates without side effects.
authors.affiliation: Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.
authors.forename: Jee Hoon
authors.initials: JH
authors.lastname: Roh
authors.forename: David M
authors.initials: DM
authors.lastname: Holtzman