title: Case vignettes and other brain teasers of monoclonal gammopathies.
abstract: There are a number of rare monoclonal gammopathies that do not have a characteristic laboratory, imaging, or pathologic study. Recognition requires keeping the specific syndrome in mind. This article reviews 6 rare syndromes associated with monoclonal proteins and gives specific "pearls" so a clinician can be certain not to overlook these important disorders that easily can be misdiagnosed as MGUS, Waldenstrom, and multiple myeloma.
authors.affiliation: Department of Hematology, Mayo Clinic, Rochester, MN 55905, USA. gertm@mayo.edu
authors.forename: Morie
authors.initials: M
authors.lastname: Gertz
authors.forename: Francis K
authors.initials: FK
authors.lastname: Buadi
mesh_terms: D000686:Amyloidosis / Q000175:diagnosis; D003937:Diagnosis, Differential; D005198:Fanconi Syndrome / Q000175:diagnosis; D005260:Female; D006388:Hemagglutinins / Q000378:metabolism; D006405:Hematology / Q000379:methods*; D006801:Humans; D007075:Immunoglobulin M / Q000378:metabolism; D008297:Male; D009101:Multiple Myeloma / Q000175:diagnosis; D016878:POEMS Syndrome / Q000175:diagnosis; D010265:Paraproteinemias / Q000175:diagnosis* / Q000628:therapy*; D053718:Scleromyxedema / Q000175:diagnosis; D013577:Syndrome
chemical_list: D006388:Hemagglutinins; D007075:Immunoglobulin M