title: [Stepwise treatment of multiple cerebral aneurysms utilizing surgical and endovascular techniques].
abstract: To evaluate results of combined treatment of multiple intracranial aneurysms utilizing microsurgical clipping with endovascular techniques. Study group comprised 60 patients with 230 multiple aneurysms (MA) of different location. Most common were aneurysms of ICA--49% and MCA--24%. Single-side ICA aneurysms were found in 11 (18.3%) patients, two-sides ICA lesions in 25 (41.7%); single-side ICA aneurysm with posterior circulation aneurysm--11 (18.3%) and two-sides ICA aneurysm with posterior circulation aneurysm in 13 (21.7%). All patients were treated with endovascular coiling followed by direct surgery. Eight patients treated in acute stage of SAH. Two-stage surgery was performed in 49 cases, three-stage treatment--in 11 cases yielding 131 operations total. Time break between surgeries was 1 day to 4 month. Total occlusion was achieved in 95.3% cases, 98 aneurysms were clipped, 64 (33.4%) coiled. In 15 (7.8%) patients aneurysms were excluded with stent or balloon assisting techniques. Six aneurysms were treated with flow diverters (Pipeline Embolisation Device). Palliative treatment (ICA occlusion with balloon or coils and aneuryms wrapping) were performed in 4.7%. There were no fatal outcomes or complications required repeated surgery in the group. Multimodal approach that combines endovascular techniques with microsurgery is an effective option in multiple aneurysm treatment. Updated endovascular modalities and direct surgery together become a treatment of choice for MA patient improving radical exclusion rate and outcomes. Combined treatment is specifically indicated for elaborate MA cases requiring multiple approaches.
authors.forename: A S
authors.initials: AS
authors.lastname: Kheĭreddin
authors.forename: S B
authors.initials: SB
authors.lastname: Iakovlev
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Filatov
authors.forename: Sh Sh
authors.initials: ShSh
authors.lastname: Éliava
authors.forename: O B
authors.initials: OB
authors.lastname: Belousova
authors.forename: A V
authors.initials: AV
authors.lastname: Bocharov
authors.forename: A N
authors.initials: AN
authors.lastname: Kaftenov
authors.forename: K G
authors.initials: KG
authors.lastname: Mikeladze
authors.forename: E V
authors.initials: EV
authors.lastname: Vinogradov
mesh_terms: D000293:Adolescent; D000328:Adult; D002548:Cerebral Revascularization / Q000379:methods*; D057510:Endovascular Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012189:Retrospective Studies