title: [Immunosuppressive drugs, corticosteroids and pregnancy].
abstract: With more than 830,000 live births in France, a great number of women are concerned by a long term treatment during pregnancy and many questions revolve around appreciating medication-related risks during pregnancy. This drug exposure concerns immunosuppressive drugs for inflammatory diseases and autoimmune diseases or organ transplantation involving more and more women of childbearing age. Here we will discuss the main immunosuppressive drugs classes (from chemical treatment until biological treatment with monoclonal antibodies) used during pregnancy for indicating the risks of these therapies, with an update of their use in pregnant women and for emphasizing the points whose use during pregnancy is most likely to cause concern.
authors.affiliation: UMR-S767 Inserm-université Paris-Descartes "Grossesse normale et pathologique", faculté des sciences pharmaceutiques et biologiques, 75006 Paris, France. sophie.gil@parisdescartes.fr
authors.forename: Sophie
authors.initials: S
authors.lastname: Gil
mesh_terms: D001327:Autoimmune Diseases / Q000188:drug therapy; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008431:Maternal-Fetal Exchange; D016377:Organ Transplantation; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D012216:Rheumatic Diseases / Q000188:drug therapy
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents