title: Sequencing and phylogenetic characterisation of a fatal Crimean - Congo haemorrhagic fever case imported into the United Kingdom, October 2012.
abstract: A patient with fever, and haemorrhagic symptoms was admitted to a hospital in Glasgow on 2 October 2012. Since he had returned from Afghanistan, serum samples were sent for diagnosis at the Rare and Imported Pathogens Laboratory, where a real-time reverse transcriptase-PCR diagnosis of Crimean – Congo haemorrhagic fever was made within 3 hrs after receipt of the sample. Hereafter the patient was transferred to a high-security infectious diseases unit in London but died on 6 October.
authors.affiliation: Microbiology Services Division, Health Protection Agency, Salisbury, United Kingdom.
authors.forename: B
authors.initials: B
authors.lastname: Atkinson
authors.forename: J
authors.initials: J
authors.lastname: Latham
authors.forename: J
authors.initials: J
authors.lastname: Chamberlain
authors.forename: C
authors.initials: C
authors.lastname: Logue
authors.forename: L
authors.initials: L
authors.lastname: O'Donoghue
authors.forename: J
authors.initials: J
authors.lastname: Osborne
authors.forename: G
authors.initials: G
authors.lastname: Carson
authors.forename: T
authors.initials: T
authors.lastname: Brooks
authors.forename: M
authors.initials: M
authors.lastname: Carroll
authors.forename: M
authors.initials: M
authors.lastname: Jacobs
authors.forename: S
authors.initials: S
authors.lastname: Hopkins
authors.forename: R
authors.initials: R
authors.lastname: Hewson
mesh_terms: D000346:Afghanistan / Q000453:epidemiology; D015415:Biomarkers; D004196:Disease Outbreaks; D003225:Hemorrhagic Fever Virus, Crimean-Congo; D006479:Hemorrhagic Fever, Crimean / Q000175:diagnosis / Q000401:mortality*; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis; D007075:Immunoglobulin M / Q000096:biosynthesis; D008131:London / Q000453:epidemiology; D008297:Male; D008969:Molecular Sequence Data; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000379:methods; D014195:Travel; D014479:United Arab Emirates / Q000453:epidemiology
chemical_list: D015415:Biomarkers; D007074:Immunoglobulin G; D007075:Immunoglobulin M