title: Anti-N-methyl-D-aspartate receptor encephalitis.
abstract: A case of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis with an atypical finding of transient increased intracranial pressure is reported. Anti-NMDAR encephalitis is an underrecognized, novel and treatable form of encephalitis being increasingly identified as an explanation of encephalitis in young adults. Management of these patients requires a multidisciplinary approach involving neurologists, internists, nursing and rehabilitation staff. It is important for internists to recognize this condition and consider it in the differential diagnosis of encephalopathy. Internists also need to be familiar with the clinical manifestations and the treatment of the disease as they have an important role in the care of these patients during their prolonged stay in the hospital. Increased intracranial pressure is an atypical and underrecognized finding that has been only noted in a previous review on this disorder. It may present a diagnostic or management challenge in patients with anti-NMDAR encephalitis.
authors.affiliation: Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas 79430, USA. yik.lim@ttuhsc.edu
authors.forename: Sian Y
authors.initials: SY
authors.lastname: Lim
authors.forename: Ragesh
authors.initials: R
authors.lastname: Panikkath
authors.forename: Charoen
authors.initials: C
authors.lastname: Mankongpaisarnrung
authors.forename: Ebtesam
authors.initials: E
authors.lastname: Islam
authors.forename: Zachary
authors.initials: Z
authors.lastname: Mulkey
authors.forename: Kenneth
authors.initials: K
authors.lastname: Nugent
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D060426:Anti-N-Methyl-D-Aspartate Receptor Encephalitis / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*; D000906:Antibodies / Q000097:blood / Q000134:cerebrospinal fluid; D003937:Diagnosis, Differential; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007167:Immunotherapy; D019586:Intracranial Hypertension / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy*; D008297:Male; D010956:Plasmapheresis; D016194:Receptors, N-Methyl-D-Aspartate / Q000276:immunology; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D000906:Antibodies; D016756:Immunoglobulins, Intravenous; D016194:Receptors, N-Methyl-D-Aspartate