title: Lost in presumption: stochastic reactions in spatial models.
abstract: Physical modeling is increasingly important for generating insights into intracellular processes. We describe situations in which combined spatial and stochastic aspects of chemical reactions are needed to capture the relevant dynamics of biochemical systems.
authors.affiliation: Department of Cell and Molecular Biology, Science for Life Laboratory, Uppsala University, Sweden.
authors.forename: Anel
authors.initials: A
authors.lastname: Mahmutovic
authors.forename: David
authors.initials: D
authors.lastname: Fange
authors.forename: Otto G
authors.initials: OG
authors.lastname: Berg
authors.forename: Johan
authors.initials: J
authors.lastname: Elf
mesh_terms: D000465:Algorithms; D002468:Cell Physiological Phenomena; D003198:Computer Simulation; D004058:Diffusion; D008954:Models, Biological; D056004:Molecular Dynamics Simulation; D013269:Stochastic Processes