title: [Epley's manoeuvre versus Epley's manoeuvre plus labyrinthine sedative in the management of benign paroxysmal positional vertigo: prospective, randomised study].
abstract: OBJECTIVE
  To compare the efficacy of Epley's manoeuvre and Epley's manoeuvre plus labyrinthine sedative in the treatment of benign paroxysmal positional vertigo.
  
  
  METHODS
  Eighty-four patients with benign paroxysmal positional vertigo were included in a randomized study. Forty-two cases in control group were treated with Epley's manoeuvre alone and the other 42 cases in treated group received Epley's manoeuvre together with Betahistine mesilate tablets, flunarizine hydrochloride, and extract of Ginkgo biloba leaves tablets. Both groups were analyzed after one week and four weeks, and recurrence was observed after half a year.
  
  
  RESULTS
  After one week treatment, cure rate and total effective rate of treated group was higher than that of control group (78.57% vs. 50.00% and 92.86% vs. 80.95%, P < 0.05, respectively). After four weeks treatment, there was no significant difference in cure rate and total effective rate between two groups (80.95% vs. 71.43% and 95.24% vs. 90.48%, P > 0.05, respectively). After half year, recurrence was found in 3 patients in treated group compared with 7 patients in control group (7.14% vs. 16.67%), and the difference was statistically significant (P < 0.05).
  
  
  CONCLUSIONS
  Epley's manoeuvre is the best treatment method of benign paroxysmal positional vertigo together with the medicine. It is easy, safe and effective, and the healing time can be shortened.
authors.affiliation: Department of Otolaryngology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou,450014, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.forename: Manying
authors.initials: M
authors.lastname: Geng
authors.forename: Baoxing
authors.initials: B
authors.lastname: Yan
authors.forename: Xing
authors.initials: X
authors.lastname: Lu
mesh_terms: D000328:Adult; D000368:Aged; D065635:Benign Paroxysmal Positional Vertigo; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D026201:Musculoskeletal Manipulations; D016896:Treatment Outcome; D014717:Vertigo / Q000188:drug therapy / Q000628:therapy*
chemical_list: D006993:Hypnotics and Sedatives