title: The efficacy of 8% Arginine-CaCO₃ applications on dentine hypersensitivity following periodontal therapy: a clinical and scanning electron microscopic study.
abstract: OBJECTIVE
  Periodontal therapy is one of the etiological factors of dentine hypersensitivity (DH). This study aimed to evaluate the efficacy of %8Arginine-CaCO₃ on DH that affects patients after periodontal treatment.
  
  
  METHODS
  Seventy-one teeth from the volunteers (n=36) with history of DH caused by periodontal therapy were included in this study, and randomly divided into two groups: group-1, who received 8%Arginine-CaCO₃ and group-2, who received 1.23%NaF-gel. The clinical indices were recorded at first visit.DH was evaluated by using tactile, air-blast, and thermal stimuli. The subject's response was recorded at baseline, immediately (Day-0) and one month after the application.
  
  
  CONCLUSIONS
  The results were statistically analyzed, and it was found that 8% Arginine-CaCO₃ treatment was more effective than 1.23% NaF-gel at time intervals. Sensitivity score differences between the groups were statistically significant at Day-28. The 8% Arginine-CaCO₃ group exhibited statistically significant reduction in DH on three stimuli at baseline to Day-28. It was concluded that 8% Arginine-CaCO₃ is more effective than 1.23% NaF-gel in reduction of patients' pain.
authors.affiliation: Gazi University, Faculty of Dentistry, Department of Periodontology, 84. Sokak, 8. Cadde, Emek, 06510 Ankara, Turkey. ahuuraz@gazi.edu.tr
authors.forename: Ahu
authors.initials: A
authors.lastname: Uraz
authors.forename: Özge
authors.initials: Ö
authors.lastname: Erol-Şimşek
authors.forename: Selcen
authors.initials: S
authors.lastname: Pehlivan
authors.forename: Zekiye
authors.initials: Z
authors.lastname: Suludere
authors.forename: Belgin
authors.initials: B
authors.lastname: Bal
mesh_terms: D000328:Adult; D001120:Arginine / Q000008:administration & dosage*; D002119:Calcium Carbonate / Q000008:administration & dosage*; D003807:Dentin Sensitivity / Q000188:drug therapy* / Q000473:pathology; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008855:Microscopy, Electron, Scanning; D010510:Periodontal Diseases / Q000628:therapy
chemical_list: D004338:Drug Combinations; D001120:Arginine; D002119:Calcium Carbonate