title: A case of immunoglobulin E mediated anaphylaxis to levodropropizine.
abstract: We experienced a case of immunoglobulin E (IgE) mediated anaphylaxis to levodropropizine. The patient was an 18-year old Korean woman. After taking the common cold medication including acetaminophen, domperidone, and levodropropizine, skin rash, angioedema and anaphylaxis were developed immediately. As she was tolerable to acetaminophen alone, we thought the culprit agent was maybe a levodropropizine tablet. To confirm the culprit, she underwent skin prick test and oral drug provocation test with the suspected one. Finally we detected levodropropizine specific IgE and confirmed the specificity by inhibition enzyme-linked immunosorbent assay (ELISA).
authors.affiliation: Division of Allergy and Immunology, Department of Internal Medicine, 2Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Kyung Hee
authors.initials: KH
authors.lastname: Park
authors.forename: Il Seon
authors.initials: IS
authors.lastname: Yun
authors.forename: Soo-Young
authors.initials: SY
authors.lastname: Choi
authors.forename: Jae-Hyun
authors.initials: JH
authors.lastname: Lee
authors.forename: Chein-Soo
authors.initials: CS
authors.lastname: Hong
authors.forename: Jung-Won
authors.initials: JW
authors.lastname: Park
mesh_terms: D000293:Adolescent; D000707:Anaphylaxis / Q000139:chemically induced* / Q000276:immunology*; D000996:Antitussive Agents / Q000009:adverse effects*; D001985:Bronchial Provocation Tests; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D011409:Propylene Glycols / Q000009:adverse effects*; D012882:Skin Tests
chemical_list: D000996:Antitussive Agents; D011409:Propylene Glycols; D007073:Immunoglobulin E; C035916:dipropizine