title: Shedding light on apoptosis at subcellular membranes.
abstract: Regulation of apoptosis by Bcl-2 family proteins is a paradigm for complex protein-protein and protein-membrane systems. Elucidating the molecular mechanisms of these interactions in vitro in live cells and in animal studies has been significantly enhanced by using fluorescence techniques.
authors.affiliation: Department of Biochemistry, McMaster University, Hamilton, Ontario L8S 4L8, Canada.
authors.forename: Justin
authors.initials: J
authors.lastname: Kale
authors.forename: Qian
authors.initials: Q
authors.lastname: Liu
authors.forename: Brian
authors.initials: B
authors.lastname: Leber
authors.forename: David W
authors.initials: DW
authors.lastname: Andrews
mesh_terms: D000818:Animals; D017209:Apoptosis; D005453:Fluorescence; D006801:Humans; D007425:Intracellular Membranes / Q000378:metabolism*; D008928:Mitochondria / Q000378:metabolism; D051336:Mitochondrial Membranes / Q000378:metabolism; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000378:metabolism*
chemical_list: D019253:Proto-Oncogene Proteins c-bcl-2