title: In vitro antioxidant potential study of some synthetic quinoxalines.
abstract: In continuation of our study the in vitro antioxidant activity of some novel quinoxaline derivatives was investigated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) method with respect to ascorbic acid. To determine the antioxidant activity, a number of substituted indoxyls (3A-G), cyclic ketones (2A-G), and quinoxalines (1A-G) were synthesized by both microwave and conventional heating methods. The present findings revealed that some quinoxalines and their precursors (1D, 1F, 1G and 2E) exhibited a marked scavenging effect on DPPH radical.
authors.affiliation: Department of Chemistry, Jahangirnagar University, Savar, Dhaka. chemmamun2@yahoo.com
authors.forename: M M
authors.initials: MM
authors.lastname: Hossain
authors.forename: M M
authors.initials: MM
authors.lastname: Hossain
authors.forename: M H
authors.initials: MH
authors.lastname: Muhib
authors.forename: M R
authors.initials: MR
authors.lastname: Mia
authors.forename: S
authors.initials: S
authors.lastname: Kumar
authors.forename: S A
authors.initials: SA
authors.lastname: Wadud
mesh_terms: D000975:Antioxidants / Q000494:pharmacology*; D001205:Ascorbic Acid / Q000494:pharmacology*; D016166:Free Radical Scavengers; D006801:Humans; D066298:In Vitro Techniques; D011810:Quinoxalines / Q000138:chemical synthesis / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D016166:Free Radical Scavengers; D011810:Quinoxalines; D001205:Ascorbic Acid