title: Targeting cancer stem cells via dendritic-cell vaccination.
abstract: Using syngeneic murine tumor models established in immunocompetent hosts, we showed that cancer stem cells are immunogenic and can be selectively targeted by dendritic cell-based vaccines. This new approach induced both humoral and cellular immune responses and conferred significantly superior antitumor immunity as compared with conventional vaccines.
authors.affiliation: Department of Internal Medicine; University of Michigan; Ann Arbor, MI USA.
authors.forename: Seagal
authors.initials: S
authors.lastname: Teitz-Tennenbaum
authors.forename: Max S
authors.initials: MS
authors.lastname: Wicha
authors.forename: Alfred E
authors.initials: AE
authors.lastname: Chang
authors.forename: Qiao
authors.initials: Q
authors.lastname: Li