title: Rational design and development of near-infrared-emitting firefly luciferins available in vivo.
authors.affiliation: Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan.
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Kojima
authors.forename: Hideo
authors.initials: H
authors.lastname: Takakura
authors.forename: Takeaki
authors.initials: T
authors.lastname: Ozawa
authors.forename: Yukio
authors.initials: Y
authors.lastname: Tada
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Nagano
authors.forename: Yasuteru
authors.initials: Y
authors.lastname: Urano
mesh_terms: D000818:Animals; D001665:Binding Sites; D001896:Boron Compounds / Q000737:chemistry; D002232:Carbocyanines / Q000737:chemistry; D045744:Cell Line, Tumor; D048888:Fireflies / Q000201:enzymology*; D049454:Firefly Luciferin / Q000737:chemistry* / Q000378:metabolism; D031541:Fluorescence Resonance Energy Transfer; D005456:Fluorescent Dyes / Q000737:chemistry; D057809:HEK293 Cells; D006801:Humans; D049409:Luciferases, Firefly / Q000737:chemistry / Q000378:metabolism; D051379:Mice; D008819:Mice, Nude; D062105:Molecular Docking Simulation; D017434:Protein Structure, Tertiary; D045663:Quantum Dots; D012107:Research Design; D012984:Software; D019265:Spectroscopy, Near-Infrared; D014183:Transplantation, Heterologous; D014184:Transplantation, Homologous
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D002232:Carbocyanines; D005456:Fluorescent Dyes; C501744:indotricarbocyanine; D049454:Firefly Luciferin; D049409:Luciferases, Firefly