title: iPiG: integrating peptide spectrum matches into genome browser visualizations.
abstract: Proteogenomic approaches have gained increasing popularity, however it is still difficult to integrate mass spectrometry identifications with genomic data due to differing data formats. To address this difficulty, we introduce iPiG as a tool for the integration of peptide identifications from mass spectrometry experiments into existing genome browser visualizations. Thereby, the concurrent analysis of proteomic and genomic data is simplified and proteomic results can directly be compared to genomic data. iPiG is freely available from https://sourceforge.net/projects/ipig/. It is implemented in Java and can be run as a stand-alone tool with a graphical user-interface or integrated into existing workflows. Supplementary data are available at PLOS ONE online.
authors.affiliation: Research Group Bioinformatics, NG4, Robert Koch-Institute, Berlin, Germany.
authors.forename: Mathias
authors.initials: M
authors.lastname: Kuhring
authors.forename: Bernhard Y
authors.initials: BY
authors.lastname: Renard
mesh_terms: D003196:Computer Graphics; D030562:Databases, Protein; D023281:Genomics; D010455:Peptides / Q000737:chemistry* / Q000235:genetics; D040901:Proteomics; D014584:User-Computer Interface
chemical_list: D010455:Peptides