title: Long-term home monitoring of hypermotor seizures by patient-worn accelerometers.
abstract: Long-term home monitoring of epileptic seizures is not feasible with the gold standard of video/electro-encephalography (EEG) monitoring. The authors developed a system and algorithm for nocturnal hypermotor seizure detection in pediatric patients based on an accelerometer (ACM) attached to extremities. Seizure detection is done using normal movement data, meaning that the system can be installed in a new patient's room immediately as prior knowledge on the patient's seizures is not needed for the patient-specific model. In this study, the authors compared video/EEG-based seizure detection with ACM data in seven patients and found a sensitivity of 95.71% and a positive predictive value of 57.84%. The authors focused on hypermotor seizures given the availability of this seizure type in the data, the typical occurrence of these seizures during sleep, i.e., when the measurements were done, and the importance of detection of hypermotor seizures given their often refractory nature and the possible serious consequences. To our knowledge, it is the first detection system focusing on this type of seizure in pediatric patients.
authors.affiliation: Dept. of Pediatric Neurology, Antwerp University Hospital, University of Antwerp, Belgium. anouk.van.de.vel@uza.be
authors.forename: Anouk
authors.initials: A
authors.lastname: Van de Vel
authors.forename: Kris
authors.initials: K
authors.lastname: Cuppens
authors.forename: Bert
authors.initials: B
authors.lastname: Bonroy
authors.forename: Milica
authors.initials: M
authors.lastname: Milosevic
authors.forename: Sabine
authors.initials: S
authors.lastname: Van Huffel
authors.forename: Bart
authors.initials: B
authors.lastname: Vanrumste
authors.forename: Lieven
authors.initials: L
authors.lastname: Lagae
authors.forename: Berten
authors.initials: B
authors.lastname: Ceulemans
mesh_terms: D061725:Accelerometry / Q000379:methods*; D000293:Adolescent; D000465:Algorithms; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual / Q000706:statistics & numerical data; D004569:Electroencephalography; D004576:Electromyography; D005260:Female; D006699:Home Care Services; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008991:Monitoring, Physiologic; D009069:Movement Disorders / Q000175:diagnosis* / Q000209:etiology*; D012640:Seizures / Q000150:complications* / Q000175:diagnosis; D017603:Signal Detection, Psychological; D014743:Videotape Recording