title: Novel drugs and treatment strategies for HIV-1.
abstract: XIX International Conference of the International AIDS Society. Washington DC, USA, 22-27 July 2012. Exploring new approaches in the development of HIV-1 therapeutics is an important component in a multifaceted approach to combating global HIV-1/AIDS-related mortality. This meeting report describes novel concepts of three eminent investigators speaking at a session of the XIX International Conference of the International AIDS Society. This conference attracted approximately 24,000 delegates comprising patients, scientists, clinicians and other key stakeholders. Herein, three putative targets of novel therapy are described: initial CD8-positive T-cell responses to HIV-1 infection, integration of HIV-1 provirus and removal of proviral DNA from host cells.
authors.affiliation: Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XW, UK. chrisjkward@gmail.com
authors.forename: Christopher James Kevin
authors.initials: CJ
authors.lastname: Ward
mesh_terms: D000818:Animals; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D018414:CD8-Positive T-Lymphocytes / Q000276:immunology; D055808:Drug Discovery; D015658:HIV Infections / Q000188:drug therapy* / Q000201:enzymology / Q000276:immunology*; D019428:HIV Integrase Inhibitors; D015497:HIV-1; D006801:Humans; D007167:Immunotherapy; D011948:Receptors, Antigen, T-Cell
chemical_list: D044966:Anti-Retroviral Agents; D019428:HIV Integrase Inhibitors; D011948:Receptors, Antigen, T-Cell