title: [Effects of yijing recipe on sperm apoptosis and mitochondrial membrane potential in patients with idiopathic oligoathenoteratospermia].
abstract: OBJECTIVE
  To investigate the effects of Yijing Recipe on sperm apoptosis and mitochondrial membrane potential (MMP) in patients with idiopathic oligoathenoteratospermia.
  
  
  METHODS
  Using the self-control method, we examined sperm apoptosis and MMP in 30 patients with oligoathenoteratospermia before and after treated with Yijing Recipe.
  
  
  RESULTS
  The rates of early sperm apoptosis (AV +/PI -) and MMP loss were significantly reduced after treatment as compared with pre-medication ([2.86 +/- 1.47]% vs [4.26 +/- 2.79]% and [21.77 +/- 13.46]% vs [41.73 +/- 20.30]%, P<0.05). No statistically significant difference was observed in the sperm death rate (PI+) before and after treatment ([34.10 +/- 16.26]% vs [30.21 +/- 13.50]%, P>0.05).
  
  
  CONCLUSIONS
  Yijing Recipe can reduce early sperm apoptosis and improve MMP, which may be one of the mechanisms underlying its efficacy on oligoathenoteratospermia.
authors.affiliation: Department of Andrology, Guang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100053, China. yzhjiao@126.com
authors.forename: Yong-Zheng
authors.initials: YZ
authors.lastname: Jiao
authors.forename: Ling-Dong
authors.initials: LD
authors.lastname: Meng
authors.forename: Wei-Guo
authors.initials: WG
authors.lastname: Ma
authors.forename: Jin-Ming
authors.initials: JM
authors.lastname: Jia
mesh_terms: D000328:Adult; D017209:Apoptosis / Q000187:drug effects*; D053627:Asthenozoospermia / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology; D008297:Male; D053078:Membrane Potential, Mitochondrial / Q000187:drug effects*; D009845:Oligospermia / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology; D008517:Phytotherapy; D055101:Semen Analysis; D013081:Sperm Motility; D013094:Spermatozoa
chemical_list: D004365:Drugs, Chinese Herbal