title: Design of irreversible optical nanothermometers for thermal ablations.
abstract: Nanothermometers composed from a gold nanorod core, temperature sensitive linker and fluorescent dye are reported. The nanothermometers have low fluorescence due to a self-quenching mechanism at temperatures below 50 °C and become highly fluorescence above 70 °C.
authors.affiliation: Department of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.
authors.forename: Tiffany P
authors.initials: TP
authors.lastname: Gustafson
authors.forename: Qian
authors.initials: Q
authors.lastname: Cao
authors.forename: Steven T
authors.initials: ST
authors.lastname: Wang
authors.forename: Mikhail Y
authors.initials: MY
authors.lastname: Berezin
mesh_terms: D003374:Coumarins / Q000737:chemistry; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry; D006046:Gold / Q000737:chemistry; D036103:Nanotechnology / Q000379:methods*; D013050:Spectrometry, Fluorescence; D013696:Temperature; D013821:Thermometers
chemical_list: D003374:Coumarins; D005456:Fluorescent Dyes; C088959:7-diethylaminocoumarin-3-carboxylic acid; D006046:Gold