title: Cellular reprogramming in pursuit of immortality.
abstract: The discovery that phenotypic diversity among differentiated cells results from epigenetic and not genetic differences, and can be reset to restore pluripotency, promises revolutionary advances in medicine. I discuss how this and related seminal discoveries have brought us to an exciting future.
authors.affiliation: Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, UK. a.surani@gurdon.cam.ac.uk
authors.forename: M Azim
authors.initials: MA
authors.lastname: Surani
mesh_terms: D000818:Animals; D002461:Cell Line, Transformed; D065150:Cellular Reprogramming / Q000235:genetics*; D019976:Cloning, Organism; D044127:Epigenesis, Genetic; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology; D051379:Mice; D014981:Xenopus