title: Increased AST/ALT ratio in azotaemic dogs infected with Babesia canis.
abstract: The AST/ALT ratio was estimated in 182 dogs infected with Babesia canis. Among these dogs 65 had anaemia and 68 were azotaemic. Student's t test was used to compare means of the AST/ALT ratio in anaemic and non-anaemic dogs, and in azotaemic and non-azotaemic dogs (p < 0.05). The differences in AST/ALT ratio between anaemic (1.52 +/- 1.15) and non-anaemic (1.76 +/- 1.34) dogs were statistically insignificant (p = 0.23), however, the comparison of AST/ALT ratio between azotaemic (2.68 +/- 1.52) and non-azotaemic (1.08 +/- 0.53) dogs revealed a significantly higher value of this index in azotaemic dogs (p = 0.00). The present results suggest that kidney injury contributed to increased AST activity in these dogs.
authors.affiliation: Division of Parasitology and Parasitic Diseases, Department of Preclinical Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences--SGGW, Ciszewskiego 8, 02-786 Warsaw, Poland. wojciechzygner@yahoo.pl
authors.forename: W
authors.initials: W
authors.lastname: Zygner
authors.forename: O
authors.initials: O
authors.lastname: Gójska-Zygner
authors.forename: L J
authors.initials: LJ
authors.lastname: Norbury
authors.forename: H
authors.initials: H
authors.lastname: Wedrychowicz
mesh_terms: D000410:Alanine Transaminase / Q000097:blood*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood*; D053099:Azotemia / Q000097:blood / Q000662:veterinary*; D001403:Babesia / Q000145:classification*; D001404:Babesiosis / Q000097:blood / Q000662:veterinary*; D004283:Dog Diseases / Q000097:blood*; D004285:Dogs
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase