title: Crosstalk between regulatory T cells (Tregs) and myeloid derived suppressor cells (MDSCs) during melanoma growth.
abstract: Myeloid derived suppressor cells (MDSCa) are a heterogeneous population of cells that promote an immunosuppressive environment in tumor-bearing hosts. Recently, B7-H1 signaling has been reported to be critical for the maintainancer of regulatory T cells (Tregs), another immunosuppressive cell population. Here, we discuss the immunosuppressive function of B7-H1 on MDSCs, and the functional crosstalk between Tregs and MDSCs.
authors.affiliation: Department of Dermatology; Tohoku University Graduate School of Medicine; Sendai, Japan.
authors.forename: Taku
authors.initials: T
authors.lastname: Fujimura
authors.forename: Yumi
authors.initials: Y
authors.lastname: Kambayashi
authors.forename: Setsuya
authors.initials: S
authors.lastname: Aiba