title: Features of the behavior of 4-amino-5-carboxamido-1,2,3-triazole in multicomponent heterocyclizations with carbonyl compounds.
abstract: Multicomponent reactions involving polyfunctional 4-amino-5-carboxamido-1,2,3-triazole and cyclic carbonyl-containing CH-acids were studied under conventional thermal heating, microwave and ultrasonic irradiation. The features of the reactions studied were discussed and the optimized procedures for the synthesis of final triazolopyrimidines were elaborated. In contrast to the similar MCRs of numerous other aminoazoles, a change of direction of the heterocyclizations in the case of 4-amino-5-carboxamido-1,2,3-triazole was not observed when microwave or thermal heating was substituted by ultrasonication at ambient temperature.
authors.affiliation: Division of Chemistry of Functional Materials, State Scientific Institution "Institute for Single Crystals" of National Academy of Sciences of Ukraine, Lenin Ave. 60, 61158 Kharkiv, Ukraine ; Fachbereich Chemie, Universität Konstanz, Fach M-720, Universitätsstrasse 10, 78457 Konstanz, Germany.
authors.forename: Eugene S
authors.initials: ES
authors.lastname: Gladkov
authors.forename: Katerina A
authors.initials: KA
authors.lastname: Gura
authors.forename: Svetlana M
authors.initials: SM
authors.lastname: Sirko
authors.forename: Sergey M
authors.initials: SM
authors.lastname: Desenko
authors.forename: Ulrich
authors.initials: U
authors.lastname: Groth
authors.forename: Valentin A
authors.initials: VA
authors.lastname: Chebanov