title: [How to explain antibiotic resistance?].
abstract: Antibiotic resistance has become a global health concern in community as well as in hospitals. The current situation leads in some cases to real therapeutic dead ends. The aim of this synthesis is to explain the reasons which allowed, after only a few decades of antibiotic use, emergence and dissemination of bacteria hard, or even impossible to treat.
authors.affiliation: Laboratoire de microbiologie, institut Gustave-Roussy, CLCC, 94800 Villejuif, France. paul-louis.woerther@igr.fr
authors.forename: Paul-Louis
authors.initials: PL
authors.lastname: Woerther
authors.forename: Antoine
authors.initials: A
authors.lastname: Andremont
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000600:supply & distribution; D001424:Bacterial Infections / Q000188:drug therapy; D055808:Drug Discovery; D024881:Drug Resistance, Bacterial / Q000235:genetics; D014943:Global Health; D006801:Humans; D011159:Population Surveillance
chemical_list: D000900:Anti-Bacterial Agents