title: Relationship between age and prostate size.
abstract: In a community-based study, the relationship between age and human prostate size was investigated in a population of men between the ages of 40 and 70 years to determine the normal prostate increase curve equation. One thousand male volunteers were randomly recruited from the Shanghai community, and the length, width, height, volume of the transition zone (TZ) and the whole prostates were measured by transrectal ultrasound (TRUS). Each volunteer was evaluated by the International Prostate Symptom Score (IPSS). Among those who completed the examination, the mean prostate parameters were all positively associated with increased age. There were statistically significant differences between each age group (P<0.05). The mean transition zone volume (TZV) had a higher increase rate with age than the mean total prostate volume (TPV), indicating that the enlargement of the TZ contributed the most to the increase in TPV. While all prostate parameters were positively correlated with the IPSS, the strongest correlation was associated with the TZ length (TZL) and TZV. The growth curve equations for prostate width, height and length were also positively associated with increasing age.
authors.affiliation: Department of Ultrasound, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China.
authors.forename: Shi-Jun
authors.initials: SJ
authors.lastname: Zhang
authors.forename: Hai-Ning
authors.initials: HN
authors.lastname: Qian
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhao
authors.forename: Kai
authors.initials: K
authors.lastname: Sun
authors.forename: Hui-Qing
authors.initials: HQ
authors.lastname: Wang
authors.forename: Guo-Qing
authors.initials: GQ
authors.lastname: Liang
authors.forename: Feng-Hua
authors.initials: FH
authors.lastname: Li
authors.forename: Zheng
authors.initials: Z
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging; D002681:China; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011467:Prostate / Q000033:anatomy & histology / Q000000981:diagnostic imaging*; D011470:Prostatic Hyperplasia / Q000000981:diagnostic imaging; D014463:Ultrasonography