title: Different secretory repertoires control the biomineralization processes of prism and nacre deposition of the pearl oyster shell.
abstract: Mollusca evolutionary success can be attributed partly to their efficiency to sustain and protect their soft body with an external biomineralized structure, the shell. Current knowledge of the protein set responsible for the formation of the shell microstructural polymorphism and unique properties remains largely patchy. In Pinctada margaritifera and Pinctada maxima, we identified 80 shell matrix proteins, among which 66 are entirely unique. This is the only description of the whole "biomineralization toolkit" of the matrices that, at least in part, is thought to regulate the formation of the prismatic and nacreous shell layers in the pearl oysters. We unambiguously demonstrate that prisms and nacre are assembled from very different protein repertoires. This suggests that these layers do not derive from each other.
authors.affiliation: Ifremer, Centre Ifremer du Pacifique, Unité Mixte de Recherche 241 Ecosystèmes Insulaires Océaniens, Tahiti, 98719 Taravao, French Polynesia. bmarie@mnhn.fr
authors.forename: Benjamin
authors.initials: B
authors.lastname: Marie
authors.forename: Caroline
authors.initials: C
authors.lastname: Joubert
authors.forename: Alexandre
authors.initials: A
authors.lastname: Tayalé
authors.forename: Isabelle
authors.initials: I
authors.lastname: Zanella-Cléon
authors.forename: Corinne
authors.initials: C
authors.lastname: Belliard
authors.forename: David
authors.initials: D
authors.lastname: Piquemal
authors.forename: Nathalie
authors.initials: N
authors.lastname: Cochennec-Laureau
authors.forename: Frédéric
authors.initials: F
authors.lastname: Marin
authors.forename: Yannick
authors.initials: Y
authors.lastname: Gueguen
authors.forename: Caroline
authors.initials: C
authors.lastname: Montagnani
mesh_terms: D000818:Animals; D005075:Biological Evolution; D002119:Calcium Carbonate / Q000737:chemistry; D019143:Evolution, Molecular; D005786:Gene Expression Regulation; D007150:Immunohistochemistry; D008969:Molecular Sequence Data; D008974:Mollusca / Q000502:physiology; D060734:Nacre / Q000378:metabolism; D049911:Pinctada / Q000737:chemistry / Q000502:physiology*; D017434:Protein Structure, Tertiary; D020543:Proteome; D040901:Proteomics / Q000379:methods; D014158:Transcription, Genetic; D059467:Transcriptome
chemical_list: D060734:Nacre; D020543:Proteome; D002119:Calcium Carbonate