title: Adherence to and beliefs in lipid-lowering medical treatments: a structural equation modeling approach including the necessity-concern framework.
abstract: OBJECTIVE
  This study attempts to identify a structure among patient-related factors that could predict treatment adherence in statin patients, especially with regards to the necessity-concern framework.
  
  
  METHODS
  414 Swedish patients using statins completed a questionnaire about their health, treatment, locus of control, perception of necessity-concern and adherence. The data were handled using a structural equation modeling approach.
  
  
  RESULTS
  Patients that reported high perceptions of necessity to treatment seemed to adhere well, and side effects appear to affect adherence negatively. Disease burden, cardiovascular disease experience and high locus of control seem to have mediating effects on adherence.
  
  
  CONCLUSIONS
  This study provides support for the hypothesis that health- and treatment-related factors, as well as locus of control factors, are indirectly associated with treatment adherence via their association with mediating factor necessity.
  
  
  CONCLUSIONS
  This study highlights the importance of considering patients' beliefs about medications, disease burden, experience of cardiovascular events and locus of control as these factors are associated with adherence behavior to statin treatment. This study also emphasizes more generally the importance of an approach targeting necessity and concern when communicating with and treating patients with lipid-lowering medication.
authors.affiliation: Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden. erik.berglund@pubcare.uu.se
authors.forename: Erik
authors.initials: E
authors.lastname: Berglund
authors.forename: Per
authors.initials: P
authors.lastname: Lytsy
authors.forename: Ragnar
authors.initials: R
authors.lastname: Westerling
mesh_terms: D002755:Choice Behavior; D006801:Humans; D008297:Male; D011795:Surveys and Questionnaires; D014956:Writing