title: PEM anchorage on titanium using catechol grafting.
abstract: BACKGROUND
  This study deals with the anchorage of polyelectrolyte films onto titanium surfaces via a cathecol-based linker for biomedical applications.
  
  
  METHODS
  The following study uses a molecule functionalized with a catechol and a carboxylic acid: 3-(3,4-dihydroxyphenyl)propanoic acid. This molecule is anchored to the TiO(2) substrate via the catechol while the carboxylic acid reacts with polymers bearing amine groups. By providing a film anchorage of chemisorption type, it makes possible to deposit polyelectrolytes on the surface of titanium.
  
  
  RESULTS
  Infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), contact angle and atomic force microscopy (AFM) measurements show that the different steps of grafting have been successfully performed.
  
  
  CONCLUSIONS
  This method based on catechol anchorage of polyelectrolytes open a window towards large possibilities of clinical applications.
authors.affiliation: Université Paris 13, Sorbonne Paris Cité, BPC, Villetaneuse, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Marie
authors.forename: Amélie
authors.initials: A
authors.lastname: Barrere
authors.forename: Frederic
authors.initials: F
authors.lastname: Schoenstein
authors.forename: Frédérique
authors.initials: F
authors.lastname: Schoentstein
authors.forename: Marie-Hélène
authors.initials: MH
authors.lastname: Chavanne
authors.forename: Brigitte
authors.initials: B
authors.lastname: Grosgogeat
authors.forename: Laurence
authors.initials: L
authors.lastname: Mora
mesh_terms: D002396:Catechols / Q000737:chemistry*; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis*; D004573:Electrolytes / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D010666:Phenylpropionates / Q000737:chemistry*; D056951:Photoelectron Spectroscopy; D011108:Polymers / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
chemical_list: D002396:Catechols; D020099:Coated Materials, Biocompatible; D004573:Electrolytes; D010666:Phenylpropionates; D011108:Polymers; D014025:Titanium; C034221:catechol