title: Hypocalcemia: a sometimes overlooked cause of heart failure in the elderly.
abstract: Heart failure, a common condition affecting older patients, is associated with increased hospitalization and mortality rates among geriatric patients. We describe the case of an 86-year-old woman with moderate renal failure, who presented pulmonary edema and severe myocardial dysfunction due to hypocalcemia. Renal failure, but also the combination of additional factors, may have contributed to hypocalcemia, including vitamin D deficiency, loop diuretics and glucocorticoid therapy - which alone can give rise to sodium retention and calciuresis, and worsens hypocalcemia. Although in animal experiments hypocalcemia has been shown to lead to cardiac decompensation, heart failure from hypocalcemia is quite rare in clinical practice. Calcium plays a key role in cardiac muscle contraction and metabolism. It is recommended that physicians check serum calcium levels in the elderly, as hypocalcemia is a reversible cause of heart failure.
authors.affiliation: Department of Internal Medicine, University of Messina, Messina, Italy. catalanoantonino@libero.it
authors.forename: Antonino
authors.initials: A
authors.lastname: Catalano
authors.forename: Giorgio
authors.initials: G
authors.lastname: Basile
authors.forename: Antonino
authors.initials: A
authors.lastname: Lasco
mesh_terms: D000369:Aged, 80 and over; D002118:Calcium / Q000097:blood; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000209:etiology*; D006801:Humans; D006996:Hypocalcemia / Q000097:blood / Q000150:complications*
chemical_list: D002118:Calcium