title: [Two cases of anaphylactoid reaction after administration of sugammadex].
abstract: Anaphylaxis during anesthesia is a rare but life-threatening event. Sugammadex is a recently introduced drug that was specifically designed for the reversal of rocuroium and vecuronium-induced neuromuscular block. We describe the cases of a 74-year-old man and a 29-year-old man who developed an anaphylactoid reaction to sugammadex, presenting with cardiovascular collapse. Initial management consisted of fluid administration and intermittent i.v. ephedrine, epinephrine, and hydrocortisone. The patients made uncomplicated recovery and were discharged.
authors.affiliation: Department of Anesthesiology, Tokushima University Hospital, Tokushima 770-8503.
authors.forename: Naohiro
authors.initials: N
authors.lastname: Ohshita
authors.forename: Yasuo M
authors.initials: YM
authors.lastname: Tsutsumi
authors.forename: Asuka
authors.initials: A
authors.lastname: Kasai
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Soga
authors.forename: Tomomi
authors.initials: T
authors.lastname: Kanamura
authors.forename: Toshiko
authors.initials: T
authors.lastname: Katayama
authors.forename: Akio
authors.initials: A
authors.lastname: Iseki
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Tomiyama
authors.forename: Katsuya
authors.initials: K
authors.lastname: Tanaka
mesh_terms: D000328:Adult; D000368:Aged; D000707:Anaphylaxis / Q000139:chemically induced*; D006801:Humans; D008297:Male; D003473:Neuromuscular Nondepolarizing Agents / Q000037:antagonists & inhibitors*; D000077122:Sugammadex; D047408:gamma-Cyclodextrins / Q000009:adverse effects*
chemical_list: D003473:Neuromuscular Nondepolarizing Agents; D047408:gamma-Cyclodextrins; D000077122:Sugammadex