title: Is there a benefit to a routine preoperative screening of infectivity for HIV, hepatitis B and C virus before elective orthopaedic operations?
abstract: OBJECTIVE
  Before elective operations, particularly orthopaedic surgery, national guidelines in Germany recommend testing for human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) to reduce the risk of transmission of the virus through a needlestick or cutting injury. Such testing is expensive. The number of new and unknown diagnoses of viral infections that can be detected by routine screening has not yet been evaluated.
  
  
  METHODS
  The aim of our department of orthopaedic surgery is to screen every adult patient listed for an operation for HBV, HCV and HIV. We retrospectively analysed the number of operations in this single centre from 2001 to 2010, correlated this number with the total number of screens and calculated the number of newly diagnosed infections. An additional cost:benefit ratio was calculated.
  
  
  RESULTS
  A total of 20,869 operations were performed by the department between 2001 and 2010. After exclusion of all interventions in children and all patients who had multiple operations, 15,482 patients remained. Test results were found for 10,011 of these patients during this period (screening rate 65 %). Of those screened, in only four cases (0.4 ‰) was a previously unknown infection detected.
  
  
  CONCLUSIONS
  Two-thirds of the patients included in our study actually underwent screening; this rate was lower than expected. The incidence of newly detected infections was low, putting the benefit of a routine preoperative screening for HBV, HCV and HIV into question. From an economic point of view the low detection rate is a strong argument in favour of omitting routine preoperative screening. Screening only those patients with risk factors may be as safe as screening every patient and would help reduce costs.
authors.affiliation: Department of Orthopedic Surgery, University Hospital, Ludwig-Maximilians-University (LMU), Campus Grosshadern, Marchioninistr. 15, 81377, Munich, Germany. patrick.weber@med.uni-muenchen.de
authors.forename: P
authors.initials: P
authors.lastname: Weber
authors.forename: J
authors.initials: J
authors.lastname: Eberle
authors.forename: J R
authors.initials: JR
authors.lastname: Bogner
authors.forename: F
authors.initials: F
authors.lastname: Schrimpf
authors.forename: V
authors.initials: V
authors.lastname: Jansson
authors.forename: S
authors.initials: S
authors.lastname: Huber-Wagner
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003362:Cost-Benefit Analysis; D017558:Elective Surgical Procedures / Q000706:statistics & numerical data*; D005858:Germany; D006678:HIV / Q000302:isolation & purification; D015658:HIV Infections / Q000175:diagnosis*; D016174:Hepacivirus / Q000302:isolation & purification; D006509:Hepatitis B / Q000175:diagnosis*; D006515:Hepatitis B virus / Q000302:isolation & purification; D006526:Hepatitis C / Q000175:diagnosis*; D006801:Humans; D018580:Mandatory Testing / Q000191:economics / Q000706:statistics & numerical data*; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult