title: [Possibilities of treatment of dystonic syndromes with akineton].
abstract: Treatment of dystonia is a complex problem of current neurology due to the etiological and neurochemical heterogeneity of this clinical syndrome. Central cholinolytics is a most effective group of drugs for patients with dystonia and dystonic tremor. The authors present the results of the successful treatment with biperiden (akineton), a centrally active anticholinergic drug with additional peripheral choline- and ganglion-blocking effect in cervical dystonia. The time of response to treatment and duration of clinical effect, its possible predictors are analyzed. Perspectives of using cholinolytics in treatment of different forms of dystonic hyperkineses are discussed.
authors.forename: A V
authors.initials: AV
authors.lastname: Karabanov
authors.forename: S N
authors.initials: SN
authors.lastname: Illarioshkin
mesh_terms: D000328:Adult; D001712:Biperiden / Q000627:therapeutic use*; D018680:Cholinergic Antagonists / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008538:Meige Syndrome / Q000188:drug therapy*; D008875:Middle Aged; D014103:Torticollis / Q000188:drug therapy*
chemical_list: D018680:Cholinergic Antagonists; D001712:Biperiden