title: Potential role of taurine in the prevention of diabetes and metabolic syndrome.
abstract: Metabolic syndrome is characterized by the cluster of a number of metabolic abnormalities in the presence of underlying insulin resistance. The prevalence of metabolic syndrome has steadily increased in all populations worldwide. Taurine (2-aminoethanesulfonic acid) is a sulfur-containing amino acid that is involved in a variety of physiological functions. Clinical and experimental studies show that taurine intake may be beneficial in the prevention of metabolic syndrome including diabetes, obesity, dyslipidemia, and hypertension. This article reviews the effect of taurine on all of the components of metabolic syndrome. In addition, the possible mechanisms by which taurine prevents diabetes and metabolic syndrome are also discussed. Further study is needed to determine the role of taurine in the development of metabolic syndrome in humans, because there is presently limited clinical data available.
authors.affiliation: R&D Laboratories, Self Medication Business, Taisho Pharmaceutical Co. Ltd, 403, Yoshino-cho 1-chome, Kita-ku, Saitama-shi, Saitama, 331-9530, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Imae
authors.forename: Toshiki
authors.initials: T
authors.lastname: Asano
authors.forename: Shigeru
authors.initials: S
authors.lastname: Murakami
mesh_terms: D000818:Animals; D003920:Diabetes Mellitus / Q000378:metabolism / Q000473:pathology; D050171:Dyslipidemias / Q000378:metabolism / Q000473:pathology; D006801:Humans; D024821:Metabolic Syndrome / Q000378:metabolism* / Q000473:pathology; D013654:Taurine / Q000378:metabolism*
chemical_list: D013654:Taurine