title: Routine screening for Cushing's syndrome is not required in patients presenting with hirsutism.
abstract: BACKGROUND
  Prevalence of Cushing's syndrome (CS) in patients presenting with hirsutism is not well known.
  
  
  OBJECTIVE
  Screening of CS in patients with hirsutism.
  
  
  METHODS
  Referral hospital.
  
  
  METHODS
  This study was carried out on 105 patients who were admitted to the Endocrinology Department with the complaint of hirsutism.
  
  
  METHODS
  All the patients were evaluated with low-dose dexamethasone suppression test (LDDST) for CS.
  
  
  METHODS
  Response to LDDST in patients presenting with hirsutism.
  
  
  RESULTS
  All the patients had suppressed cortisol levels following low-dose dexamethasone administration excluding CS. The etiology of hirsutism was polycystic ovary syndrome in 79%, idiopathic hirsutism in 13%, idiopathic hyperandrogenemia in 6%, and nonclassical congenital hyperplasia in 2% of the patients.
  
  
  CONCLUSIONS
  Routine screening for CS in patients with a referral diagnosis of hirsutism is not required. For the time being, diagnostic tests for CS in hirsute patients should be limited to patients who have accompanying clinical stigmata of hypercortisolism.
authors.affiliation: Departments of Endocrinology, Erciyes University Medical School, 38039 Kayseri, Turkey. fktimur@erciyes.edu.tr
authors.forename: Z
authors.initials: Z
authors.lastname: Karaca
authors.forename: B
authors.initials: B
authors.lastname: Acmaz
authors.forename: G
authors.initials: G
authors.lastname: Acmaz
authors.forename: F
authors.initials: F
authors.lastname: Tanriverdi
authors.forename: K
authors.initials: K
authors.lastname: Unluhizarci
authors.forename: S
authors.initials: S
authors.lastname: Aribas
authors.forename: Y
authors.initials: Y
authors.lastname: Sahin
authors.forename: F
authors.initials: F
authors.lastname: Kelestimur
mesh_terms: D000293:Adolescent; D000328:Adult; D003480:Cushing Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology*; D003907:Dexamethasone; D005260:Female; D005498:Follicular Phase / Q000097:blood; D005938:Glucocorticoids; D006628:Hirsutism / Q000097:blood / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D017588:Hyperandrogenism / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D006965:Hyperplasia; D010044:Outpatient Clinics, Hospital; D010050:Ovarian Function Tests; D010053:Ovary / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D011085:Polycystic Ovary Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D015995:Prevalence; D062606:Tertiary Care Centers; D014421:Turkey / Q000453:epidemiology; D055815:Young Adult
chemical_list: D005938:Glucocorticoids; D003907:Dexamethasone; D006854:Hydrocortisone