title: Anterior mediastinal gastroenteric cyst containing pancreatic tissue influenced the diabetes mellitus status.
abstract: The mediastinal gastroenteric cyst is a rare developmental cyst. In general, the majority of mediastinal gastroenteric cysts are recognized in infancy and are commonly located in the posterior mediastinum. In addition, gastroenteric cysts occasionally contain pancreatic tissue; however, no studies have reported that these cysts influenced the diabetes mellitus status of the patient. We report here an extremely rare case of an adult gastroenteric cyst with pancreatic tissue originating from the anterior mediastinum, influencing the severity of diabetes mellitus in a patient. This case report presents two remarkable findings. First, the location of the gastroenteric cyst (anterior mediastinum) and the patient's age at the time of detection (adulthood) were extremely rare. Secondly, the present case is also unusual in terms of glycometabolism. As this tumour decreased in size, the glycosylated haemoglobin value increased, which suggested a worsening of the patient's diabetes mellitus. The diabetes mellitus further worsened after removal of the tumour.
authors.affiliation: Department of Thoracic Surgery, Clinical Research Institute, National Hospital Organization, Kyushu Medical Center, Fukuoka, Japan. fshoji@surg2.med.kyushu-u.ac.jp
authors.forename: Fumihiro
authors.initials: F
authors.lastname: Shoji
authors.forename: Sadanori
authors.initials: S
authors.lastname: Takeo
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Shikada
authors.forename: Masakazu
authors.initials: M
authors.lastname: Katsura
mesh_terms: D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D001786:Blood Glucose / Q000378:metabolism; D002828:Choristoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D003920:Diabetes Mellitus / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D018450:Disease Progression; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008297:Male; D008476:Mediastinal Cyst / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D008875:Middle Aged; D010179:Pancreas; D011237:Predictive Value of Tests; D020545:Respiratory Mucosa; D013270:Stomach; D020775:Thoracic Surgery, Video-Assisted; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; C517652:hemoglobin A1c protein, human