title: The Chelsea critical care physical assessment tool (CPAx): validation of an innovative new tool to measure physical morbidity in the general adult critical care population; an observational proof-of-concept pilot study.
abstract: OBJECTIVE
  To develop a scoring system to measure physical morbidity in critical care - the Chelsea Critical Care Physical Assessment Tool (CPAx).
  
  
  METHODS
  The development process was iterative involving content validity indices (CVI), a focus group and an observational study of 33 patients to test construct validity against the Medical Research Council score for muscle strength, peak cough flow, Australian Therapy Outcome Measures score, Glasgow Coma Scale score, Bloomsbury sedation score, Sequential Organ Failure Assessment score, Short Form 36 (SF-36) score, days of mechanical ventilation and inter-rater reliability.
  
  
  METHODS
  Trauma and general critical care patients from two London teaching hospitals.
  
  
  RESULTS
  Users of the CPAx felt that it possessed content validity, giving a final CVI of 1.00 (P<0.05). Construct validation data showed moderate to strong significant correlations between the CPAx score and all secondary measures, apart from the mental component of the SF-36 which demonstrated weak correlation with the CPAx score (r=0.024, P=0.720). Reliability testing showed internal consistency of α=0.798 and inter-rater reliability of κ=0.988 (95% confidence interval 0.791 to 1.000) between five raters.
  
  
  CONCLUSIONS
  This pilot work supports proof of concept of the CPAx as a measure of physical morbidity in the critical care population, and is a cogent argument for further investigation of the scoring system.
authors.affiliation: Chelsea and Westminster NHS Foundation Trust, 369 Fulham Road, London SW10 9NH, UK. evelyn.corner@chelwest.nhs.uk
authors.forename: E J
authors.initials: EJ
authors.lastname: Corner
authors.forename: H
authors.initials: H
authors.lastname: Wood
authors.forename: C
authors.initials: C
authors.lastname: Englebretsen
authors.forename: A
authors.initials: A
authors.lastname: Thomas
authors.forename: R L
authors.initials: RL
authors.lastname: Grant
authors.forename: D
authors.initials: D
authors.lastname: Nikoletou
authors.forename: N
authors.initials: N
authors.lastname: Soni
mesh_terms: D003371:Cough; D003422:Critical Care; D004185:Disability Evaluation; D005260:Female; D017144:Focus Groups; D015600:Glasgow Coma Scale; D006784:Hospitals, Teaching; D006801:Humans; D008131:London; D008297:Male; D051346:Mobility Limitation; D009102:Multiple Organ Failure / Q000175:diagnosis; D053580:Muscle Strength; D017063:Outcome Assessment, Health Care; D010865:Pilot Projects; D011187:Posture; D011237:Predictive Value of Tests; D011446:Prospective Studies; D015203:Reproducibility of Results; D012121:Respiration, Artificial