title: Divergent effects of desferrioxamine on bacterial growth and characteristics.
abstract: Desferrioxamines (DF's) are siderophores produced by some groups of bacteria. Previously, we discovered that DFE, produced by Streptomyces griseus, induced divergent developmental phenotypes in various Streptomyces isolates. In this study, we isolated bacteria whose phenotype was affected by the presence of 0.1 mM DFB from soil samples, and studied their phylogenetic position via 16 S rRNA gene-based analysis. Isolates belonging to Microbacterium grew only in the presence of DFB in the medium. DFB promoted growth of some isolates, while significantly inhibiting that of other divergent bacteria. Different groups of isolates were affected, not because of growth-related changes, but because of changes in the colony morphology based on possible stimulation of motility. An isolate affiliated with Janthinobacterium was stimulated for violacein production as well as for pilus formation. The wide and divergent effects of DFB suggest that availability of siderophores significantly affect the structure of microbial community.
authors.affiliation: Life Science Research Center, College of Bioresource Sciences, Nihon University, Kanagawa, Japan.
authors.forename: Daisei
authors.initials: D
authors.lastname: Eto
authors.forename: Kenta
authors.initials: K
authors.lastname: Watanabe
authors.forename: Hisafumi
authors.initials: H
authors.lastname: Saeki
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Oinuma
authors.forename: Ko-ichi
authors.initials: K
authors.lastname: Otani
authors.forename: Megumi
authors.initials: M
authors.lastname: Nobukuni
authors.forename: Hatsumi
authors.initials: H
authors.lastname: Shiratori-Takano
authors.forename: Hideaki
authors.initials: H
authors.lastname: Takano
authors.forename: Teruhiko
authors.initials: T
authors.lastname: Beppu
authors.forename: Kenji
authors.initials: K
authors.lastname: Ueda
mesh_terms: D001419:Bacteria / Q000187:drug effects* / Q000235:genetics / Q000254:growth & development / Q000648:ultrastructure; D003470:Culture Media; D003676:Deferoxamine / Q000494:pharmacology*; D008855:Microscopy, Electron, Scanning; D010641:Phenotype; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012988:Soil Microbiology; D013305:Streptomyces griseus / Q000378:metabolism
chemical_list: D003470:Culture Media; D012336:RNA, Ribosomal, 16S; D003676:Deferoxamine