title: [Specific features of the clinical picture and course of familial dilated cardiomyopathy].
abstract: OBJECTIVE
  To study prevalence, clinical and hemodynamic features, and life prognosis in patients with familial dilated cardiomyopathy (DCM).
  
  
  METHODS
  Two hundred and forty-four patients with DCM were examined during the period 2000 to 2010. According to their medical history records and the results of clinical and functional studies, familial cardiomyopathy was diagnosed in 29 (11.8%) of 244 patients. For comparative assessment, the authors formed two groups: 1) 29 patients with the familial form of DCM and 2) 83 patients with its sporadic form. Their examination included ECG, Holter ECG monitoring, 6-minute walk test, X-ray cardiometry, coronarography, and life prognosis assessment.
  
  
  RESULTS
  It has been established that the prevalence of the familial form of DCM accounts for 11.9% and is, unlike its non-familial form, associated with younger age; it is maternally inherited in one third of cases and characterized by the development of complete atrioventricular block in some patients.
  
  
  CONCLUSIONS
  Investigating the life prognosis of the patients has shown that the familial form and age less than 30 years are characterized by a rapidly progressing course accompanied by a significant increase in death rates within the first 12 follow-up months.
authors.forename: N A
authors.initials: NA
authors.lastname: Kurbanov
authors.forename: R D
authors.initials: RD
authors.lastname: Kurbanov
authors.forename: T A
authors.initials: TA
authors.lastname: Abdullaev
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002311:Cardiomyopathy, Dilated / Q000145:classification / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology; D004562:Electrocardiography; D015716:Electrocardiography, Ambulatory; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011379:Prognosis; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed; D055815:Young Adult