title: Optical coherence tomography for multifocal vitelliform macular dystrophy.
abstract: OBJECTIVE
  To describe the optical coherence tomography (OCT) features of multifocal vitelliform macular dystrophy (VMD).
  
  
  METHODS
  Five patients (10 eyes) with multifocal VMD were examined by slit lamp biomicroscopy, fundus photography, and OCT.
  
  
  RESULTS
  Serous retinal detachment was present in the macular area in all eyes. A hyperreflective inner/outer segment interface was observed in the macula in nine of them. High reflectivity was homogeneous in six eyes of three patients with no prominent macular lesion. Retinoschisis-like changes could be clearly seen in four eyes evaluated by high-resolution OCT. A hyporeflectivity corresponded to the inner nuclear layer in two eyes. In four eyes with prominent macular lesions, a hyperreflective area between the hyporeflective outer nuclear layer and the hyperreflective retinal pigment epithelium layer was detectable.
  
  
  CONCLUSIONS
  Although the fundus appearance of multifocal VMD is quite variable, OCT features of the disease are relatively uniform. Optical coherence tomography could help the pathological interpretation and facilitate the diagnosis of VMD.
authors.affiliation: Qingdao Eye Hospital, Shandong Eye Institute, Shandong Academy of Medical Sciences, Qingdao, China. chxhf@126.com
authors.forename: Haifeng
authors.initials: H
authors.lastname: Xu
authors.forename: Liang
authors.initials: L
authors.lastname: Ying
authors.forename: Ping
authors.initials: P
authors.lastname: Lin
authors.forename: Jie
authors.initials: J
authors.lastname: Wu
mesh_terms: D000328:Adult; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D055213:Retinal Pigment Epithelium / Q000473:pathology; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity; D057826:Vitelliform Macular Dystrophy / Q000175:diagnosis* / Q000503:physiopathology