title: Recurrences in tuberculosis in a cohort of human immunodeficiency virus-infected patients: the influence of highly active antiretroviral therapy.
abstract: BACKGROUND
  Little is known about recurrent tuberculosis (TB) among HIV-infected patients and the influence of highly active antiretroviral therapy (HAART).
  
  
  METHODS
  A population-based retrospective longitudinal study was conducted on all HIV-infected TB patients in Barcelona (Spain) notified in 1987-2003, and followed up until 2005. TB recurrence and HAART influence were analysed according to calendar period.
  
  
  RESULTS
  Patients with no-treatment and those in pre-HAART had more risk of TB recurrence (RR: 2.3; CI: 1-5.8 and RR: 4.8; CI: 2-12).
  
  
  CONCLUSIONS
  HAART decreases probability of TB recurrence and should be extended to all cases.
authors.affiliation: Epidemiology Service, Public Health Agency of Barcelona, Spain. jmillet@aspb.es
authors.forename: Juan-Pablo
authors.initials: JP
authors.lastname: Millet
authors.forename: Angels
authors.initials: A
authors.lastname: Orcau
authors.forename: Martí
authors.initials: M
authors.lastname: Casals
authors.forename: Patricia
authors.initials: P
authors.lastname: Garcia de Olalla
authors.forename: Joan A
authors.initials: JA
authors.lastname: Caylà
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D015897:Comorbidity; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012042:Registries; D012189:Retrospective Studies; D012306:Risk; D013030:Spain / Q000453:epidemiology; D014376:Tuberculosis / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents