title: Association of vitamin D deficiency and anemia in a hospitalized geriatric population: denutrition as a confounding factor.
abstract: This study aimed to investigate the association between vitamin D deficiency and anemia in a hospitalized geriatric population. An observational study, at the acute care geriatric unit of Brest Hospital, France, was conducted among 226 patients aged ≥70 years consecutively hospitalized between January 22, 2010 and August 9, 2010. Vitamin D and hemoglobin levels were measured. Vitamin D deficiency was defined as a 25(OH)D level <50 nmol/L and anemia as defined by the World Health Organization. After adjustment for albuminemia, anemia was not significantly associated with vitamin D deficiency (odds ratio (OR) = 1.37; 95 % confidence interval (CI) = 0.72-2.6). But anemia was significantly associated with hypoalbuminemia (OR = 2.08; 95 % CI = 1.11-3.91). Denutrition reflected by hypoalbuminemia could be a possible confounding factor in the previously described association between anemia and vitamin D deficiency.
authors.affiliation: Acute Geriatric Unit Teaching Hospital, CHRU Brest, bd Tanguy Prigent, Brest, France. ancou_61@hotmail.com
authors.forename: A
authors.initials: A
authors.lastname: Coutard
authors.forename: R
authors.initials: R
authors.lastname: Garlantézec
authors.forename: S
authors.initials: S
authors.lastname: Estivin
authors.forename: M
authors.initials: M
authors.lastname: Andro
authors.forename: A
authors.initials: A
authors.lastname: Gentric
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000097:blood / Q000150:complications* / Q000453:epidemiology*; D015986:Confounding Factors, Epidemiologic; D004921:Erythropoietin / Q000097:blood; D005260:Female; D005602:France / Q000453:epidemiology; D005853:Geriatrics / Q000706:statistics & numerical data; D006454:Hemoglobins / Q000032:analysis; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D044342:Malnutrition / Q000097:blood / Q000150:complications / Q000453:epidemiology*; D010281:Parathyroid Hormone / Q000097:blood; D014807:Vitamin D / Q000097:blood; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications* / Q000453:epidemiology*
chemical_list: D006454:Hemoglobins; D010281:Parathyroid Hormone; D004921:Erythropoietin; D014807:Vitamin D