title: The osteocalcin gene rs1800247 polymorphism in Kashubian population.
abstract: Osteocalcin is the most important noncollagenous protein component of the bone. Polymorphisms of osteocalcin gene were reported to be associated with bone mineral density. However, this relation was only confirmed in some populations. In this study presence of C/T polymorphism in osteocalcin gene (rs1800247) was determined in Kashubian population (northern Poland). The frequencies of variants were CC 9 %, TC 31 %, and TT 60 %, with no significant differences between genders. The genotypes were in Hardy-Weinberg equilibrium.
authors.affiliation: Department of Allergology, Medical University of Gdansk, ul. Debinki 7, 80-952, Gdansk, Poland, specjalski@poczta.onet.pl.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Specjalski
authors.forename: Maria
authors.initials: M
authors.lastname: Porzezińska
authors.forename: Alicja
authors.initials: A
authors.lastname: Siemińska
authors.forename: Jan M
authors.initials: JM
authors.lastname: Słomiński
authors.forename: Ewa
authors.initials: E
authors.lastname: Jassem
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density / Q000235:genetics; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D015675:Osteocalcin / Q000235:genetics*; D010024:Osteoporosis / Q000453:epidemiology* / Q000208:ethnology*; D011044:Poland / Q000453:epidemiology; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D011401:Promoter Regions, Genetic / Q000235:genetics; D012737:Sex Factors; D055815:Young Adult
chemical_list: D015675:Osteocalcin