title: Inhibitory activity of chlorogenic acids in decaffeinated green coffee beans against porcine pancreas lipase and effect of a decaffeinated green coffee bean extract on an emulsion of olive oil.
abstract: A decaffeinated green coffee bean extract (DGCBE) inhibited porcine pancreas lipase (PPL) activity with an IC50 value of 1.98 mg/mL. Six different chlorogenic acids in DGCBE contributed to this PPL inhibition, accounting for 91.8% of the inhibitory activity. DGCBE increased the droplet size and decreased the specific surface area of an olive oil emulsion.
authors.affiliation: R&D Center, UCC Ueshima Coffee Co., Ltd., Osaka, Japan. yuusaku-narita@ucc.co.jp
authors.forename: Yusaku
authors.initials: Y
authors.lastname: Narita
authors.forename: Kazuya
authors.initials: K
authors.lastname: Iwai
authors.forename: Taiji
authors.initials: T
authors.lastname: Fukunaga
authors.forename: Osamu
authors.initials: O
authors.lastname: Nakagiri
mesh_terms: D000818:Animals; D055162:Biocatalysis / Q000187:drug effects; D002110:Caffeine / Q000302:isolation & purification*; D002726:Chlorogenic Acid / Q000494:pharmacology*; D040503:Coffea / Q000737:chemistry*; D004655:Emulsions; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006868:Hydrolysis / Q000187:drug effects; D008049:Lipase / Q000037:antagonists & inhibitors*; D000069463:Olive Oil; D010179:Pancreas / Q000201:enzymology*; D010938:Plant Oils / Q000737:chemistry*; D012639:Seeds / Q000737:chemistry*; D013552:Swine
chemical_list: D004655:Emulsions; D004791:Enzyme Inhibitors; D000069463:Olive Oil; D010938:Plant Oils; D002726:Chlorogenic Acid; D002110:Caffeine; D008049:Lipase