title: Human serum amyloid A (SAA) protein changes in acute epilepsy patients.
abstract: Previously, there is no study looking at serum biomarkers for epilepsy. Epilepsy can trigger neuroinflammation events, and serum amyloid A (SAA) is one biomarker as acute-phase protein in multiple diseases. In present study, we detected serum SAA peak in epileptic patients with mass spectrometry and quantified with enzyme-linked immunosorbent assay measurement. The results suggested that in acute phase of epilepsy, the serum SAA increased, but after 3 months of treatment, the SAA peak was disappeared. In conclusion, the study provided values of proteomic diagnosis of epilepsy.
authors.affiliation: The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan Province, China. epilepsy doctor@163.com
authors.forename: Guifen
authors.initials: G
authors.lastname: Li
authors.forename: Fang
authors.initials: F
authors.lastname: Ren
authors.forename: Jinhua
authors.initials: J
authors.lastname: Yao
authors.forename: Mingying
authors.initials: M
authors.lastname: Wang
authors.forename: Xianjun
authors.initials: X
authors.lastname: Feng
authors.forename: Dong
authors.initials: D
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D002648:Child; D004827:Epilepsy / Q000097:blood / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D040901:Proteomics; D012189:Retrospective Studies; D000685:Serum Amyloid A Protein / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D000685:Serum Amyloid A Protein