title: Incidental seminal vesicle amyloidosis observed in diagnostic prostate biopsies--are routine investigations for systemic amyloidosis warranted?
abstract: Seminal vesicle (SV) amyloidosis is a well-documented histological entity, but it is observed infrequently. Its incidence is on the rise, which is probably related to the increasing use of prostate biopsies to investigate patients with elevated serum prostate-specific antigen levels. Here, we report seven cases of incidental SV amyloidosis over a 3-year period and consider their relationship to the previously suggested aetiological factors. Based on our series, we conclude that incidental localized SV amyloidosis observed in diagnostic prostate biopsies does not warrant formal investigations for systemic amyloidosis.
authors.affiliation: Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland G12 8QQ, UK.
authors.forename: Zichu
authors.initials: Z
authors.lastname: Yang
authors.forename: Alexander
authors.initials: A
authors.lastname: Laird
authors.forename: Ashley
authors.initials: A
authors.lastname: Monaghan
authors.forename: Morag
authors.initials: M
authors.lastname: Seywright
authors.forename: Imran
authors.initials: I
authors.lastname: Ahmad
authors.forename: Hing Y
authors.initials: HY
authors.lastname: Leung
mesh_terms: D000328:Adult; D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis*; D001706:Biopsy; D006801:Humans; D000075363:Immunoglobulin Light-chain Amyloidosis; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000000981:diagnostic imaging* / Q000473:pathology; D017430:Prostate-Specific Antigen; D011471:Prostatic Neoplasms / Q000175:diagnosis; D012669:Seminal Vesicles / Q000473:pathology*; D014463:Ultrasonography
chemical_list: D017430:Prostate-Specific Antigen