title: [Serological investigation on Toxoplasma gondii infection in patients with unknown central nervous system diseases].
abstract: Totally 207 patients with unknown central nervous system diseases and 203 healthy persons were investigated for serum IgG of anti-Toxoplasma antibody assessed by ELISA. The serum IgG positive rate in 207 patients with unknown central nervous system diseases was 19.81%, and that in 203 health people was 5.42%, and there was a significant difference between them (P < 0.01). The IgG positive rates in different types of central nervous system diseases were different, which were 22.81%, 24.32%, 16.05%, and 18.75%, respectively in encephalopathy, epilepsy, mental disorder and neurasthenia. The IgG positive rate in different types of central nervous system diseases were significantly higher than that in healthy population (P < 0.01). The IgG positive rates in patients who contacted or did not contact cats or dogs were 32.97% and 9.48% respectively (P < 0.01). In conclusion, the infection rate in patients with unknown central nervous system diseases is higher than that in healthy persons; therefore, it is necessary to assay the serum IgG in them.
authors.affiliation: Shuyang People's Hospital, Shuyang 223600, China.
authors.forename: Zhi-Shu
authors.initials: ZS
authors.lastname: Li
authors.forename: Yu-Zheng
authors.initials: YZ
authors.lastname: Huang
authors.forename: Li-Yi
authors.initials: LY
authors.lastname: Hu
authors.forename: Guang-Sheng
authors.initials: GS
authors.lastname: Wang
authors.forename: Hai-Yong
authors.initials: HY
authors.lastname: Hua
authors.forename: Yong-Hua
authors.initials: YH
authors.lastname: Zhou
mesh_terms: D000328:Adult; D000913:Antibodies, Protozoan / Q000097:blood*; D002493:Central Nervous System Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014123:Toxoplasmosis / Q000150:complications / Q000175:diagnosis* / Q000276:immunology
chemical_list: D000913:Antibodies, Protozoan; D007074:Immunoglobulin G