title: Parvoviruses-tools to fine-tune anticancer immune responses.
abstract: Oncolytic virotherapy represents a recent approach to anticancer therapy. Rodent autonomous parvoviruses (PVs) represent naturally oncolytic viruses that are non-pathogenic for humans but possess and extended tropism, being capable of infecting transformed cells of both rodent and human origin. Recent work from our group demonstrate that PVs can act as direct lytic agents and adjuvants, stimulating antitumor immune responses against glioma and pancreatic ductal adenocarcinoma (PDAC).
authors.affiliation: Programme Infection and Cancer; Tumour Virology Division F010 and Institut National de la Santé et de la Recherche Médicale (INSERM; Unit 701; German Cancer Research Center (DKFZ); Heidelberg, Germany.
authors.forename: Svitlana P
authors.initials: SP
authors.lastname: Grekova
authors.forename: Jean
authors.initials: J
authors.lastname: Rommelaere
authors.forename: Zahari
authors.initials: Z
authors.lastname: Raykov