title: Making limbs from fins.
abstract: Our limbs evolved from fish fins as vertebrates colonized aquatic shallows and land. If we understood the genetics underlying this transition, could we build a limb on a fish? In this issue of Developmental Cell, Freitas et al. (2012) show that boosting Hoxd13 expression can bring zebrafish one step closer to terra firma.
authors.affiliation: Instituto de Ciencias Biologicas, Universidade Federal do Para, 66075 Belem, Brazil. ischneider@ufpa.br
authors.forename: Igor
authors.initials: I
authors.lastname: Schneider
authors.forename: Neil H
authors.initials: NH
authors.lastname: Shubin