title: Small nucleolar RNAs (snoRNAs) as potential non-invasive biomarkers for early cancer detection.
abstract: Small nucleolar RNAs (snoRNAs) are non-coding RNA (ncRNA) molecules, which are associated with specific proteins to form small nucleolar ribonucleoparticles. However, the function of snoRNAs in cancer still remains elusive. Recently, several independent lines of evidence have indicated that these ncRNAs might have crucial roles in controlling tumorigenesis, and snoRNAs could be potential biomarkers for cancer.
authors.affiliation: State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P. R. China.
authors.forename: Wen-Dan
authors.initials: WD
authors.lastname: Chen
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Zhu
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism*; D002471:Cell Transformation, Neoplastic; D055088:Early Detection of Cancer; D006801:Humans; D009369:Neoplasms / Q000235:genetics / Q000378:metabolism; D020537:RNA, Small Nucleolar / Q000235:genetics / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D020537:RNA, Small Nucleolar