title: Highly stereoselective glycosyl-chloride-mediated synthesis of 2-deoxyglucosides.
abstract: Cl intermediates: The glycosylation of per-O-benzylated 2-deoxy- and 2,6-dideoxythioglycosides, promoted by the combination of para-toluenesulfenyl chloride (p-TolSCl) and silver triflate (AgOTf), furnished the products in high yields and high stereoselectivity. The glycosyl chloride was the intermediate (see scheme).
authors.affiliation: Institute of Chemistry, Academia Sinica, Nankang, Taipei 115, Taiwan.
authors.forename: Ved Prakash
authors.initials: VP
authors.lastname: Verma
authors.forename: Cheng-Chung
authors.initials: CC
authors.lastname: Wang
mesh_terms: D002236:Carbohydrate Conformation; D002712:Chlorides / Q000737:chemistry*; D006027:Glycosides / Q000138:chemical synthesis* / Q000737:chemistry*; D006031:Glycosylation; D013237:Stereoisomerism
chemical_list: D002712:Chlorides; D006027:Glycosides