title: Metabolic syndrome in youth: current insights and novel serum biomarkers.
abstract: Paralleling the worldwide epidemic in childhood obesity, in the last decade we have observed a rise in the prevalence of metabolic syndrome (MetS) in pediatrics. The MetS comprises a cluster of cardiovascular risk factors. Multiple definitions have been proposed for the syndrome in the pediatric age group, but they are very difficult to test and validate. Thus, in this paper we will discuss the current knowledge in pediatric MetS and the potential role of novel biomarkers in the pathogenesis and diagnosis of MetS.
authors.affiliation: Department of Pediatrics, Yale University School of Medicine, 330 Cedar Street, PO Box 208064, New Haven, CT 06520, USA. nicola.santoro@yale.edu
authors.forename: Nicola
authors.initials: N
authors.lastname: Santoro
authors.forename: Ram
authors.initials: R
authors.lastname: Weiss
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D002648:Child; D006801:Humans; D007333:Insulin Resistance; D024821:Metabolic Syndrome / Q000097:blood* / Q000503:physiopathology
chemical_list: D015415:Biomarkers; D001786:Blood Glucose