title: Efficacy of modified constraint induced movement therapy in improving upper limb function in children with hemiplegic cerebral palsy: a randomized controlled trial.
abstract: OBJECTIVE
  The objective of this randomized single blind (outcome assessor) controlled trial was to evaluate the efficacy of 4 weeks of modified constraint induced movement therapy (mCIMT) in improving upper limb function in 3-8 years old children with hemiplegic cerebral palsy.
  
  
  METHODS
  Thirty-one children were randomly assigned to receive the mCIMT (N=16) with conventional therapy or conventional therapy alone (N=15). Children were evaluated three times (at enrollment, follow up at 4 weeks and 12 weeks). The primary outcome measure was difference in "change in mean total QUEST scores" at 4 weeks of intervention between the intervention and the control arm.
  
  
  RESULTS
  After 4 weeks of intervention, mCIMT group showed significant change in the affected upper limb in QUEST scores (10.7 ± 5.2 vs 1.4 ± 1.7, p<0.001) and time (s) to complete nine-hole-pegboard test compared with control group [60(0-130) vs 5(-12 to 30), p<0.001]. The improvement observed in upper limb function after 4 weeks of intervention persisted 8 weeks after discontinuation of intervention in mCIMT group.
  
  
  CONCLUSIONS
  The modified constraint induced movement therapy appears to be effective in improving upper limb function in 3-8 years old hemiplegic cerebral palsy children.
authors.affiliation: Department of Pediatrics, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Anita
authors.initials: A
authors.lastname: Choudhary
authors.forename: Sheffali
authors.initials: S
authors.lastname: Gulati
authors.forename: Madhulika
authors.initials: M
authors.lastname: Kabra
authors.forename: Upinder Pal
authors.initials: UP
authors.lastname: Singh
authors.forename: Naveen
authors.initials: N
authors.lastname: Sankhyan
authors.forename: Ravindra Mohan
authors.initials: RM
authors.lastname: Pandey
authors.forename: Veena
authors.initials: V
authors.lastname: Kalra
mesh_terms: D002547:Cerebral Palsy / Q000503:physiopathology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D005081:Exercise Therapy / Q000379:methods; D005260:Female; D006429:Hemiplegia / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008297:Male; D009068:Movement / Q000502:physiology*; D016037:Single-Blind Method; D016896:Treatment Outcome; D034941:Upper Extremity / Q000503:physiopathology*