title: Near efficient target allocations in response-adaptive randomization.
abstract: Traditionally optimal target allocation proportions for response-adaptive designs are derived by completely ignoring the actual adaptive randomization procedure. Considering efficiency of the allocation designs, we derive near efficient target proportions to balance between individual and collective ethics. Performance of the derived allocation targets are assessed numerically for binary, normal and exponential responses. Generalization for multiple treatments is also addressed.
authors.affiliation: Applied Statistics Unit, Indian Statistical Institute, Kolkata, India.
authors.forename: Atanu
authors.initials: A
authors.lastname: Biswas
authors.affiliation: Department of Statistics, West Bengal State University, Barasat, West Bengal, India rahul_bhattya@yahoo.com.
authors.forename: Rahul
authors.initials: R
authors.lastname: Bhattacharya
mesh_terms: D015199:Extracorporeal Membrane Oxygenation; D006801:Humans; D011897:Random Allocation; D016032:Randomized Controlled Trials as Topic / Q000379:methods*; D012107:Research Design; D006113:United Kingdom