title: [Ventricular arrhythmias and arterial hypertension: role of inflammatory biomarkers in arrhythmia development].
abstract: Arrhythmogenic role of proinflammatory cytokines is still unclear despite of wide discussion on inflammatory arrhythmogenic mechanisms. The main goal of study was to compare levels of tumor necrosis factor a, interleukin 6 and interleukin 4 in hypertensive patients with and without ventricular rhythm disturbances. The study included 100 cases, 50 of those had ventricular arrhythmias. Levels of tumor necrosis factor a, interleukin 6 and interleukin 4 were studied. Possible connections of above mentioned biomarkers with ventricular arrhythmias, blood pressure, echocardiography left ventricle data were evaluated. Higher level of biomarkers was associated with presence of ventricular arrhythmias; higher rate of ventricular extrasystoles was accompanied with insignificantly lower biomarker level.
authors.forename: L M
authors.initials: LM
authors.lastname: Vasilets
authors.forename: A V
authors.initials: AV
authors.lastname: Tuev
authors.forename: A V
authors.initials: AV
authors.lastname: Agafonov
authors.forename: E A
authors.initials: EA
authors.lastname: Ratanova
authors.forename: A A
authors.initials: AA
authors.lastname: Krivaia
authors.forename: K V
authors.initials: KV
authors.lastname: Trenogina
authors.forename: N E
authors.initials: NE
authors.lastname: Grigoriadi
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood*; D001794:Blood Pressure; D002097:C-Reactive Protein / Q000378:metabolism; D016207:Cytokines / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications* / Q000503:physiopathology; D007249:Inflammation / Q000097:blood* / Q000150:complications; D008297:Male; D008875:Middle Aged; D017180:Tachycardia, Ventricular / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D055815:Young Adult
chemical_list: D015415:Biomarkers; D016207:Cytokines; D002097:C-Reactive Protein