title: Trends in the prevalence of chronic kidney disease in Korean adults: the Korean National Health and Nutrition Examination Survey from 1998 to 2009.
abstract: BACKGROUND
  Chronic kidney disease (CKD) is associated with a poor quality of life and cardiovascular events and is a great threat to public health.
  
  
  METHODS
  We investigated the trends of CKD prevalence over 12 years in Korean adults at least 20 years old using sampling weight methods based on the Korean National Health and Nutrition Examination Survey (KNHANES) I (1998), II (2001), III (2005) and IV (2007-09). Of the 135 954 subjects participating in KNHANES I-IV, 33 276 (14 307 men, 18 969 women) were included in the present study.
  
  
  RESULTS
  The percentage of glomerular filtration rate (GFR) <60 mL/min/1.73 m(2) in KNHANES I-IV was 1.0, 5.4, 3.1 and 2.6% in men and 3.4, 9.7, 10.2 and 4.6% in women, respectively. The percentage of proteinuria ≥ 1+ measured by a dipstick method across KNHANES phases gradually declined in men (3.1, 3.0, 2.8 and 2.2% in KNHANES I-IV, respectively), while those in women rebounded in KNHANES IV after reduction through KNHANES III (3.3, 2.3, 1.4 and 1.9%, respectively). The prevalence of CKD (GFR <60 mL/min/1.73 m(2) or proteinuria ≥ 1+) in KNHANES I-IV was 3.9, 7.9, 5.4 and 4.5% in men and 6.4, 11.3, 12.0 and 6.3% in women, respectively. After stratification by age (20-39 years, 40-59 years and ≥ 60 years), the prevalence trends were similar to those before the stratification by sexes.
  
  
  CONCLUSIONS
  The prevalence of CKD in Korean adults has decreased since 2001 in men and since 2005 in women.
authors.affiliation: Department of Family Medicine, College of Medicine, Yonsei University, Seoul, Korea.
authors.forename: Hee-Taik
authors.initials: HT
authors.lastname: Kang
authors.forename: JungEun
authors.initials: J
authors.lastname: Lee
authors.forename: John A
authors.initials: JA
authors.lastname: Linton
authors.forename: Byoung-Jin
authors.initials: BJ
authors.lastname: Park
authors.forename: Yong-Jae
authors.initials: YJ
authors.lastname: Lee
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D005919:Glomerular Filtration Rate; D006801:Humans; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D015995:Prevalence; D011379:Prognosis; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology*; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D055815:Young Adult