title: [Role of endothelial glycocalyx in mechanogenic control of arterial hydraulic resistance].
abstract: The review was focused on the data demonstrating that flow induced arterial dilation depends not only on intact endothelium but on intact endothelial glycocalyx, as well. These data demonstrate that filaments of the endothelial glycocalyx serve as mechanotrasducers since their shear stress induced deformations stimulate endothelial cells to release nitric oxide.
authors.forename: A M
authors.initials: AM
authors.lastname: Mel'kumiants
mesh_terms: D000818:Animals; D001158:Arteries / Q000166:cytology / Q000502:physiology*; D002415:Cats; D004285:Dogs; D042783:Endothelial Cells / Q000166:cytology / Q000502:physiology*; D004730:Endothelium, Vascular / Q000166:cytology / Q000502:physiology*; D019276:Glycocalyx / Q000502:physiology*; D018056:Hemorheology; D006801:Humans; D040542:Mechanotransduction, Cellular; D009569:Nitric Oxide / Q000378:metabolism; D033081:Shear Strength; D014655:Vascular Resistance / Q000502:physiology*; D014661:Vasoconstriction / Q000502:physiology; D014664:Vasodilation / Q000502:physiology
chemical_list: D009569:Nitric Oxide