title: Infectious mononucleosis mimicking malignant T-cell lymphoma in the nasopharynx: a case report and review of the literature.
abstract: Infectious mononucleosis (IM) is Epstein-Barr virus-associated and self-limited lymphoproliferative disorder. The histopathologic features of the nasopharynx in IM are rarely described. In this report, we described a patient of IM with atypical T-cell proliferation in the nasopharynx. In-situ hybridization for EBV-encoded RNA with immunostaining against CD20 was used for evaluation of EBV infection. The histopathologic features of IM could mimic malignant T-cell lymphoma. It should be differentiate reactive T-cell lymphoproliferation from malignant lymphoma in the nasopharynx.
authors.affiliation: Department of Pathology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung, Taiwan.
authors.forename: Hong-Lin
authors.initials: HL
authors.lastname: He
authors.forename: Ming-Chung
authors.initials: MC
authors.lastname: Wang
authors.forename: Wan-Ting
authors.initials: WT
authors.lastname: Huang
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007244:Infectious Mononucleosis / Q000175:diagnosis*; D016399:Lymphoma, T-Cell / Q000175:diagnosis*; D009302:Nasopharyngeal Diseases / Q000175:diagnosis*; D013601:T-Lymphocytes / Q000473:pathology* / Q000821:virology