title: Case report: Transient success using prolonged treatment with miltefosine for a patient with diffuse cutaneous leishmaniasis infected with Leishmania mexicana mexicana.
abstract: Leishmania sp. is an intracellular parasite that causes a variable degree of clinical manifestations, especially in the skin. We present the case of a 38-year-old male with a chronic history of mucocutaneous disease present since childhood that generated deformity, loss of cartilage in the ears and nose, and scarring that limited his range of motion. The parasite was identified as L. mexicana mexicana. The patient was treated with a 3-month course of oral miltefosine with overwhelming results.
authors.affiliation: Department of Medicine, University Hospital Dr. José Eleuterio González, Monterrey, Nuevo Leon, México. ordaz7@hotmail.com
authors.forename: Alejandro
authors.initials: A
authors.lastname: Ordaz-Farias
authors.forename: Fania Z
authors.initials: FZ
authors.lastname: Muñoz-Garza
authors.forename: Farah K
authors.initials: FK
authors.lastname: Sevilla-Gonzalez
authors.forename: Ana
authors.initials: A
authors.lastname: Arana-Guajardo
authors.forename: Jorge
authors.initials: J
authors.lastname: Ocampo-Candiani
authors.forename: Nancy
authors.initials: N
authors.lastname: Treviño-Garza
authors.forename: Ingeborg
authors.initials: I
authors.lastname: Becker
authors.forename: Adrian
authors.initials: A
authors.lastname: Camacho-Ortiz
mesh_terms: D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D006801:Humans; D007894:Leishmania mexicana / Q000302:isolation & purification*; D016774:Leishmaniasis, Diffuse Cutaneous / Q000188:drug therapy* / Q000469:parasitology; D010767:Phosphorylcholine / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000981:Antiprotozoal Agents; D010767:Phosphorylcholine; C039128:miltefosine