title: Highly regioselective synthesis of fused seven-membered rings through copper-catalyzed cross-coupling.
abstract: A highly efficient protocol of copper catalysis for the one-pot synthesis of fused dibenzo[b,f][1,4]oxazepines is reported. The transformation involves a Smiles rearrangement, leading to the completely different regioselectivity from the classical cross-coupling. The easy reaction of aryl chlorides as substrates enhances the practical application of the methodology.
authors.affiliation: Department of Chemistry, Zhejiang University, Hangzhou 310027, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Sang
authors.forename: Ming
authors.initials: M
authors.lastname: Yu
authors.forename: Hangfei
authors.initials: H
authors.lastname: Tu
authors.forename: Jianwei
authors.initials: J
authors.lastname: Zou
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D002384:Catalysis; D003300:Copper; D010077:Oxazepines / Q000138:chemical synthesis*; D013237:Stereoisomerism
chemical_list: D010077:Oxazepines; D003300:Copper