title: [Chemical constituents of n-BuOH extract of Comastoma pedunculatum].
abstract: Thirteen compoumds were isolated from the n-BuOH portion of the 70% ethanolic extract of Comastoma pedunculatum by a combination of various chromatographic techniques including silica gel, macroporous adsorbent resin, Sephadex LH-20, and preparative HPLC, of which nine were triterpenoid saponins and four were flavone C-glycosides. Their structures were elucidated by spectroscopic data as saikogenin F (1), 3-O-beta-D-fucopyranosylsaikogenin F (2), clinoposaponin XV (3), saikosaponin A (4), 6"-acetylsaikosaponin A (5), clinoposaponin I (6), bupleuroside I (7) , clinoposaponin XII (8) , saikoponin b3 (9), isovitexin (10) , swertisin (11) , isoorientin (12), 3',4',5-trihydroxy-7-methoxy-6-C-beta-D-glucopyranosyl-flavone (13). Compounds 1-10, 12-13 were all isolated from Comastoma genus for the first time.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors.forename: Yongqi
authors.initials: Y
authors.lastname: Qiao
authors.forename: Baosong
authors.initials: B
authors.lastname: Cui
authors.forename: Li
authors.initials: L
authors.lastname: Tang
authors.forename: Jiabao
authors.initials: J
authors.lastname: Liu
authors.forename: Shuai
authors.initials: S
authors.lastname: Li
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D047309:Flavones / Q000032:analysis / Q000302:isolation & purification; D029965:Gentianaceae / Q000737:chemistry*; D012503:Saponins / Q000032:analysis / Q000302:isolation & purification; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D004365:Drugs, Chinese Herbal; D047309:Flavones; D012503:Saponins; C043562:flavone