title: A new anthraquinone glycoside from the root of Rheum officinale Baill.
abstract: A new and a known anthraquinone glycosides were isolated from the ethanol extract of the roots of Rheum officinale Baill. The extract was purified by various chromatographies, such as silica gel, Sephadex LH-20, RP-C18 column chromatography and HPLC. Two compounds were identified by the spectroscopic techniques of NMR, MS, and chemical method. In addition, they were tested for their cytotoxic effects against HepG2 cell. Unfortunately, they showed no or weak activity.
authors.affiliation: School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
authors.forename: Zheng-Xiang
authors.initials: ZX
authors.lastname: Xia
authors.forename: Zhong-Yan
authors.initials: ZY
authors.lastname: Tang
authors.forename: Rui
authors.initials: R
authors.lastname: An
authors.forename: Ye
authors.initials: Y
authors.lastname: Chen
authors.forename: Yi-Zhu
authors.initials: YZ
authors.lastname: Zhang
authors.forename: Xin-Hong
authors.initials: XH
authors.lastname: Wang
mesh_terms: D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D056945:Hep G2 Cells; D006801:Humans; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry; D012250:Rheum / Q000737:chemistry*
chemical_list: C583811:1-methyl-8-hydroxy-9,10-anthraquinone-3-O-beta-D-glucopyranoside; C554711:1-methyl-8-hydroxyl-9,10-anthraquinone-3-O-beta-D-(6'-O-cinnamoyl)glucopyranoside; D000880:Anthraquinones; D006027:Glycosides