title: [Reynolds syndrome revealing a malignant thymoma].
abstract: BACKGROUND
  Thymomas, benign or malignant, may be associated with autoimmune diseases. They are classically associated with myasthenia gravis, neuromyotonia, or pure red cell aplasia.
  
  
  METHODS
  We here report, to the best of our knowledge, the first description of an association between thymoma and Reynolds syndrome (systemic sclerosis associated with primary biliary cirrhosis) in an 80-year-old woman.
  
  
  CONCLUSIONS
  The suspected pathogenesis of this association could be a thymus escape of auto-reactive T lymphocytes and the consecutive development of an auto-immune disorder.
authors.affiliation: Service de médecine interne, hôpital de Purpan, CHU de Toulouse, Toulouse, France. michaud.m@chu-toulouse.fr
authors.forename: M
authors.initials: M
authors.lastname: Michaud
authors.forename: C
authors.initials: C
authors.lastname: Gaudin
authors.forename: D
authors.initials: D
authors.lastname: Brechemier
authors.forename: G
authors.initials: G
authors.lastname: Moulis
authors.forename: L
authors.initials: L
authors.lastname: Astudillo
authors.forename: V
authors.initials: V
authors.lastname: Lavialle-Guillotreau
authors.forename: L
authors.initials: L
authors.lastname: Balardy
mesh_terms: D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis*; D012595:Scleroderma, Systemic / Q000175:diagnosis*; D012859:Sjogren's Syndrome / Q000175:diagnosis; D013577:Syndrome; D013945:Thymoma / Q000175:diagnosis*; D013953:Thymus Neoplasms / Q000175:diagnosis*