title: Sister Mary Joseph's nodule as a first sign of pancreatic cancer.
abstract: Sister Mary Joseph's nodule (SMJN) refers to a metastatic tumor of the umbilicus. It is a rare entity which arises from a malignancy in the intra-abdominal cavity. We herein describe a patient who presented with SMJN as his first sign of pancreatic cancer. It is an even more unusual case of SMJN. We therefore, suggest that pancreatic cancer should be included in the differential diagnosis when an umbilical mass is found. With the progress made in surgical procedures and other modalities, an early diagnosis will dramatically improve the prognosis of the patients.
authors.affiliation: Department of Surgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, Zhejiang Province, China.
authors.forename: Xue-Li
authors.initials: XL
authors.lastname: Bai
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhang
authors.forename: Waqas
authors.initials: W
authors.lastname: Masood
authors.forename: Noman
authors.initials: N
authors.lastname: Masood
authors.forename: Yin
authors.initials: Y
authors.lastname: Tang
authors.forename: Chun-Hui
authors.initials: CH
authors.lastname: Cao
authors.forename: Qi-Han
authors.initials: QH
authors.lastname: Fu
authors.forename: Yun
authors.initials: Y
authors.lastname: Zhang
authors.forename: Shun-Liang
authors.initials: SL
authors.lastname: Gao
authors.forename: Ting-Bo
authors.initials: TB
authors.lastname: Liang
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000378:metabolism; D001706:Biopsy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000473:pathology; D011379:Prognosis; D058288:Sister Mary Joseph's Nodule / Q000175:diagnosis* / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology; D016896:Treatment Outcome; D014472:Umbilicus / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor