title: Common bile duct adenocarcinoma in a patient with situs inversus totalis: report of a rare case.
abstract: BACKGROUND
  Situs inversus totalis represents an unusual anomaly characterized by a mirror-image transposition of the abdominal and thoracic viscera. It often occurs concomitantly with other disorders that make difficult diagnosis and management of abdominal pathology. The relationship between situs inversus totalis and cancer remains unclear.
  
  
  METHODS
  We describe a 33-year old Guinean man with situs inversus totalis who presented with obstructive jaundice. Imaging and endoscopic modalities demonstrated a mass of distal common bile duct which biopsy identified an adenocarcinoma. The patient was successfully treated by cephalic pancreaticoduodenectomy followed by adjuvant chemoradiation and he is doing well without recurrence 8 months after surgery.
  
  
  CONCLUSIONS
  The occurrence of bile duct adenocarcinoma in patient with situs inversus totalis accounts as a rare coincidence. In this setting, when the tumor is resectable, surgical management should be considered without contraindication and must be preceded by a careful preoperative staging.
authors.affiliation: Department of medical oncology, Hassan II University Hospital, Fez, Morocco. hafida.benhammane@gmail.com
authors.forename: Hafida
authors.initials: H
authors.lastname: Benhammane
authors.forename: Saoussane
authors.initials: S
authors.lastname: Kharmoum
authors.forename: Sylvain
authors.initials: S
authors.lastname: Terraz
authors.forename: Thierry
authors.initials: T
authors.lastname: Berney
authors.forename: Thai
authors.initials: T
authors.lastname: Nguyen-Tang
authors.forename: Muriel
authors.initials: M
authors.lastname: Genevay
authors.forename: Omar
authors.initials: O
authors.lastname: El Mesbahi
authors.forename: Arnaud
authors.initials: A
authors.lastname: Roth
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000000981:diagnostic imaging; D000328:Adult; D001650:Bile Duct Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012857:Situs Inversus / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed