title: BODIPY-phosphane as a versatile tool for easy access to new metal-based theranostics.
abstract: A new BODIPY-phosphane was synthesized and proved to be a versatile tool for imaging organometallic complexes. It also led to easy access to a new family of theranostics, featuring gold, ruthenium and osmium complexes. The compounds' cytotoxicity was tested on cancer cells, and their cell uptake was followed by fluorescence microscopy in vitro.
authors.affiliation: Institut de Chimie Moléculaire de l'Université de Bourgogne, UMR 6302 CNRS, Université de Bourgogne, 9 avenue A. Savary, BP47870, 21078 Dijon, France.
authors.forename: Semra
authors.initials: S
authors.lastname: Tasan
authors.forename: Olivier
authors.initials: O
authors.lastname: Zava
authors.forename: Benoît
authors.initials: B
authors.lastname: Bertrand
authors.forename: Claire
authors.initials: C
authors.lastname: Bernhard
authors.forename: Christine
authors.initials: C
authors.lastname: Goze
authors.forename: Michel
authors.initials: M
authors.lastname: Picquet
authors.forename: Pierre
authors.initials: P
authors.lastname: Le Gendre
authors.forename: Pierre
authors.initials: P
authors.lastname: Harvey
authors.forename: Franck
authors.initials: F
authors.lastname: Denat
authors.forename: Angela
authors.initials: A
authors.lastname: Casini
authors.forename: Ewen
authors.initials: E
authors.lastname: Bodio
mesh_terms: D001896:Boron Compounds / Q000737:chemistry*; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity; D006046:Gold / Q000737:chemistry; D006801:Humans; D008670:Metals / Q000737:chemistry*; D018613:Microscopy, Confocal; D009992:Osmium / Q000737:chemistry; D010720:Phosphines / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D056831:Coordination Complexes; D008670:Metals; D010720:Phosphines; D009992:Osmium; D006046:Gold; D012428:Ruthenium; C044646:phosphine