title: Assessment of the relevance of the antibiotic 2-amino-3-(oxirane-2,3-dicarboxamido)-propanoyl-valine from Pantoea agglomerans biological control strains against bacterial plant pathogens.
abstract: The epiphyte Pantoea agglomerans 48b/90 (Pa48b) is a promising biocontrol strain against economically important bacterial pathogens such as Erwinia amylovora. Strain Pa48b produces the broad-spectrum antibiotic 2-amino-3-(oxirane-2,3-dicarboxamido)-propanoyl-valine (APV) in a temperature-dependent manner. An APV-negative mutant still suppressed the E. amylovora population and fire blight disease symptoms in apple blossom experiments under greenhouse conditions, but was inferior to the Pa48b wild-type indicating the influence of APV in the antagonism. In plant experiments with the soybean pathogen Pseudomonas syringae pv. glycinea both, Pa48b and the APV-negative mutant, successfully suppressed the pathogen. Our results demonstrate that the P. agglomerans strain Pa48b is an efficient biocontrol organism against plant pathogens, and we prove its ability for fast colonization of plant surfaces over a wide temperature range.
authors.affiliation: Institute for Microbiology, Microbial Communication, University of Jena, Neugasse 25, D-07743, Jena, Germany. ulrike.sammer@uni-jena.de
authors.forename: Ulrike F
authors.initials: UF
authors.lastname: Sammer
authors.forename: Katharina
authors.initials: K
authors.lastname: Reiher
authors.forename: Dieter
authors.initials: D
authors.lastname: Spiteller
authors.forename: Annette
authors.initials: A
authors.lastname: Wensing
authors.forename: Beate
authors.initials: B
authors.lastname: Völksch
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D023181:Antimicrobial Cationic Peptides; D015139:Blotting, Southern; D044084:Erwinia amylovora / Q000254:growth & development*; D027845:Malus; D016254:Mutagenesis, Insertional; D020636:Pantoea / Q000737:chemistry* / Q000235:genetics; D010455:Peptides / Q000494:pharmacology*; D010572:Pest Control, Biological / Q000379:methods; D010935:Plant Diseases / Q000382:microbiology* / Q000517:prevention & control*
chemical_list: C548064:2-amino-3-(oxirane-2,3-dicarboxamido)propanoylvaline; D000900:Anti-Bacterial Agents; D023181:Antimicrobial Cationic Peptides; D010455:Peptides