title: Canada's contribution to global research in cardiovascular diseases.
abstract: The burden of cardiovascular disease (CVD) in Canada and other developed countries is growing, in part because of the aging of the population and the alarming rise of obesity. Studying Canada's contribution to the global body of CVD research output will shed light on the effectiveness of investments in Canadian CVD research and inform if Canada has been responding to its CVD burden. Search was conducted using the Web-of-Science database for publications during 1981 through 2010 on major areas and specific interventions in CVD. Search was also conducted using Canadian and US online databases for patents issued between 1981 and 2010. Search data were used to estimate the proportions of the world's pool of research publications and of patents conducted by researchers based in Canada. The results indicate that Canada contributed 6% of global research in CVD during 1981 through 2010. Further, Canada's contribution shows a strong upward trend during the period. Based on patent data, Canada's contribution level was similar (5%-7%). Canada's contribution to the global pool of CVD research is on par with France and close to the UK, Japan, and Germany. Canada's contribution in global CVD research is higher than its average contribution in all fields of research (6% vs 3%). As the burden of chronic diseases including CVD rises with Canada's aging population, the increase in Canadian research into CVD is encouraging.
authors.affiliation: Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada. vanhai.nguyen@utoronto.ca
authors.forename: Hai V
authors.initials: HV
authors.lastname: Nguyen
authors.forename: Claire
authors.initials: C
authors.lastname: de Oliveira
authors.forename: Harindra C
authors.initials: HC
authors.lastname: Wijeysundera
authors.forename: William W L
authors.initials: WW
authors.lastname: Wong
authors.forename: Gloria
authors.initials: G
authors.lastname: Woo
authors.forename: Paul
authors.initials: P
authors.lastname: Grootendorst
authors.forename: Peter P
authors.initials: PP
authors.lastname: Liu
authors.forename: Murray D
authors.initials: MD
authors.lastname: Krahn
mesh_terms: D035843:Biomedical Research / Q000458:organization & administration*; D002170:Canada; D002318:Cardiovascular Diseases / Q000628:therapy*; D014943:Global Health; D006801:Humans; D007391:International Cooperation