title: [Total intravenous anaesthesia in geriatrics: the example of propofol].
abstract: The aim of this review is to analyse the changes in the pharmacology of the elderly patient using, as examples, the existing pharmacokinetics and pharmacodynamics models of propofol and data provided in the literature.
authors.affiliation: Servicio de Anestesiología, Facultad de Medicina, Clínica Alemana-Universidad del Desarrollo, Santiago, Chile. pasevou@mi.cl
authors.forename: P O
authors.initials: PO
authors.lastname: Sepúlveda Voullieme
authors.forename: L L
authors.initials: LL
authors.lastname: Abadía
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology; D000768:Anesthesia, General; D000771:Anesthesia, Intravenous; D018686:Anesthetics, Intravenous / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D008962:Models, Theoretical; D017410:Practice Guidelines as Topic; D015742:Propofol / Q000494:pharmacology / Q000627:therapeutic use*; D012143:Respiratory Physiological Phenomena
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol