title: Quinine-induced bronchiolitis obliterans and organizing pneumonia.
abstract: Quinine is a vital anti-malarial drug used in the management of resistant Falciparum malaria. There are previous reports of quinine-induced pulmonary edema and infiltrates. We report the first case of biopsy-proven bronchiolitis obliterans organizing pneumonia (BOOP), confirmed by the Naranjo Adverse Drug Reaction Probability Scale (NADRS) of 5 and a severity scale of 5, secondary to intravenous quinine, in a 15-year-old girl with Plasmodium falciparum infection after a visit to Kenya. Clinical course of the patient followed by review of the literature and appropriate medical interventions for quinine-induced BOOP are suggested.
authors.affiliation: Department of Intensive Care, Tawam Hospital in Affiliation with Johns Hopkins Medicine, Al Ain, United Arab Emirates.
authors.forename: Masoodur
authors.initials: M
authors.lastname: Rahman
authors.forename: Rayhan
authors.initials: R
authors.lastname: Hashmey
authors.forename: Said
authors.initials: S
authors.lastname: Abuhasna