title: [Clinical effects of bile aspiration just before contrast injection during endoscopic retrograde cholangiopancreatography].
abstract: OBJECTIVE
  This study was designed to determine whether bile aspiration before contrast injection cholangiogram prevent of post-ERCP cholangitis, liver function worsening, cholecystitis and pancreatitis.
  
  
  METHODS
  One hundred and two patients in the bile aspiration group before contrast injection from December 1, 2008 to December 30, 2009 and 115 patients in the conventional control group from January 1, 2010 to June 30, 2010 were analyzed. The incidence of post-ERCP cholangitis, liver function worsening, cholecystitis, pancreatitis, and hyperamylasemia only were compared between these two groups.
  
  
  RESULTS
  In the 102 patients with the bile aspiration group, post-ERCP cholangitis in 3 patients (2.9%), liver function worsening in 4 patients (3.9%), cholecystitis and pancreatitis in none, and hyperamylasemia only in 6 patients (5.8%) occurred. In the 115 patients with control group, post-ERCP cholangitis in 1 patient (0.4%), liver function worsening in 9 patients (7.8%), cholecystitis in none, pancreatitis in 3 patients (2.6%), hyperamylasemia only in 10 patients (8.6%) developed. The two groups did not significantly differ in terms of the incidence of post-ERCP cholangitis, liver function worsening, pancreatitis, and hyperamylasemia only (p>0.05).
  
  
  CONCLUSIONS
  Initially bile juice aspiration just before contrast injection into the bile duct rarely prevented post-ERCP cholangitis, liver function worsening, and pancreatitis in patients with the extrahepatic bile duct obstruction.
authors.affiliation: Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
authors.forename: Jung Sik
authors.initials: JS
authors.lastname: Choi
authors.forename: Dae Hwan
authors.initials: DH
authors.lastname: Kang
authors.forename: Hyun Dae
authors.initials: HD
authors.lastname: Kim
authors.forename: Sang Hwa
authors.initials: SH
authors.lastname: Urm
authors.forename: Sang Heun
authors.initials: SH
authors.lastname: Lee
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Kim
authors.forename: Sam Ryong
authors.initials: SR
authors.lastname: Jee
authors.forename: Eun Uk
authors.initials: EU
authors.lastname: Jung
authors.forename: Sung Jae
authors.initials: SJ
authors.lastname: Park
authors.forename: Youn Jae
authors.initials: YJ
authors.lastname: Lee
authors.forename: Sang Young
authors.initials: SY
authors.lastname: Seol
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001646:Bile; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects*; D002761:Cholangitis / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D003287:Contrast Media; D005260:Female; D006801:Humans; D034321:Hyperamylasemia / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D015994:Incidence; D008107:Liver Diseases / Q000503:physiopathology; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D013396:Suction
chemical_list: D003287:Contrast Media