title: [Antipsychotics for treatment of neuropsychiatric disorders in dementia].
abstract: Antipsychotics, when used to treat neuropsychological symptoms associated with dementia, are associated with low effectiveness but a high risk of side effects. Some of these unwanted effects are severe and include an increased rate of cerebrovascular events and increased mortality. Although neuropsychiatric symptoms are frequently associated with dementia, it appears that antipsychotics are often used without clear indications and for too long time periods. Antipsychotics should be used only when all non-pharmacological strategies have failed. A clear definition of the treatment target in advance and a continuous monitoring of the therapy are mandatory.
authors.affiliation: Klinik und Poliklinik für Psychiatrie, Universität Leipzig, Leipzig, Deutschland.
authors.forename: H-J
authors.initials: HJ
authors.lastname: Gertz
authors.forename: G
authors.initials: G
authors.lastname: Stoppe
authors.forename: B
authors.initials: B
authors.lastname: Müller-Oerlinghausen
authors.forename: L G
authors.initials: LG
authors.lastname: Schmidt
authors.forename: C
authors.initials: C
authors.lastname: Baethge
authors.forename: C
authors.initials: C
authors.lastname: Hiemke
authors.forename: K
authors.initials: K
authors.lastname: Lieb
authors.forename: T
authors.initials: T
authors.lastname: Bschor
mesh_terms: D014150:Antipsychotic Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D002561:Cerebrovascular Disorders / Q000139:chemically induced* / Q000517:prevention & control; D003704:Dementia / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D001523:Mental Disorders / Q000150:complications* / Q000188:drug therapy*; D012307:Risk Factors
chemical_list: D014150:Antipsychotic Agents