title: [Hypertensive nephrosclerosis: an exhaustive diagnosis?].
abstract: Hypertensive nephrosclerosis is a much overused clinical diagnosis, largely unsubstantiated by biopsy data. It is in fact a clinical-pathological diagnosis implying a causal role of hypertension in the associated chronic kidney disease. However, such a simple, linear causality is often not obvious or easy to demonstrate. Further factors like age, Afro-American descent, genetic and immunological factors as well as dysmetabolic syndrome may contribute to the development and progression of arterionephrosclerosis independently of hypertension.
authors.affiliation: Dipartimento di Scienze Mediche e Pediatriche, Universita' di Catania, Catania, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Malatino
authors.forename: Benedetta
authors.initials: B
authors.lastname: Stancanelli
authors.forename: Costas
authors.initials: C
authors.lastname: Giannakakis
authors.forename: Carmelita
authors.initials: C
authors.lastname: Marcantoni
mesh_terms: D018450:Disease Progression; D006801:Humans; D006977:Hypertension, Renal / Q000150:complications / Q000175:diagnosis*; D009400:Nephrosclerosis / Q000150:complications / Q000175:diagnosis*; D018570:Risk Assessment; D012307:Risk Factors