title: Quantitative evaluation of the fetal cerebellar vermis using the median view on three-dimensional ultrasound.
abstract: OBJECTIVE
  The purpose of this study was to investigate the effectiveness for quantitative evaluation of cerebellar vermis using three-dimensional (3D) ultrasound and to establish a nomogram for Chinese fetal vermis measurements during gestation.
  
  
  METHODS
  Sonographic examinations were performed in normal fetuses and in cases suspected of the diagnosis of vermian rotation. 3D median planes were obtained with both OMNIVIEW and tomographic ultrasound imaging.
  
  
  RESULTS
  Measurements of the cerebellar vermis were highly correlated between two-dimensional and 3D median planes. The diameter of the cerebellar vermis follows growth approximately predicted by the quadratic regression equation. The normal vermis was almost parallel to the brain stem, with the average angle degree to be <2° in normal fetuses. The average angle degree of the 9 cases of vermian rotation was >5°.
  
  
  CONCLUSIONS
  Three-dimensional median planes are obtained more easily than two-dimensional ones, and allow accurate measurements of the cerebellar vermis. The 3D approach may enable rapid assessment of fetal cerebral anatomy in standard examination. Measurements of cerebellar vermis may provide a quantitative index for prenatal diagnosis of posterior fossa malformations.
authors.affiliation: Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Zhao
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Ailu
authors.initials: A
authors.lastname: Cai
authors.forename: Jingyu
authors.initials: J
authors.lastname: Li
authors.forename: Lizhu
authors.initials: L
authors.lastname: Chen
authors.forename: Bing
authors.initials: B
authors.lastname: Wang
mesh_terms: D002531:Cerebellum / Q000002:abnormalities / Q000000981:diagnostic imaging*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D007223:Infant; D011247:Pregnancy; D012016:Reference Values; D014102:Torsion Abnormality / Q000000981:diagnostic imaging; D016216:Ultrasonography, Prenatal