title: Printable microfluidic systems using pressure sensitive adhesive material for biosensing devices.
abstract: BACKGROUND
  In biosensors with a fluid analyte, the integration of a microfluidic system, which guides the analyte into the sensing area, is critical. Quicker and economical ways to build up microfluidic systems will make point of care diagnostics viable. Printing is a low-cost technology that is increasingly used in emerging organic and flexible electronics and biosensors. In this paper, we present printed fluidic systems on flexible substrates made with pressure sensitive adhesive materials.
  
  
  METHODS
  Printable pressure sensitive adhesive materials have been used for making microfluidic systems. Flexible substrates have been used, and two types of adhesive materials, one thermally dried and another UV curable, have been tested. Top sealing layer was laminated directly on top of the printed microfluidic structure. Flow tests were done with deionized water.
  
  
  RESULTS
  Flow tests with deionized water show that both adhesive materials are suitable for capillary flow driven fluidic devices. Flow test using water as dielectric material was also done successfully on a printed electrolyte gated organic field effect transistor with an integrated microfluidic system.
  
  
  CONCLUSIONS
  Due to its ease of process and low cost, printed microfluidic system is believed to find more applications in biosensing devices. This article is part of a Special Issue entitled Organic Bioelectronics-Novel Applications in Biomedicine.
authors.affiliation: Acreo AB, Box 787, SE-601 17, Norrköping, Sweden. xin.wang@acreo.se
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: David
authors.initials: D
authors.lastname: Nilsson
authors.forename: Petronella
authors.initials: P
authors.lastname: Norberg
mesh_terms: D000269:Adhesives; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods*; D004581:Electronics / Q000295:instrumentation / Q000379:methods; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation* / Q000379:methods*; D011312:Pressure; D011327:Printing / Q000295:instrumentation* / Q000379:methods; D014867:Water / Q000737:chemistry
chemical_list: D000269:Adhesives; D014867:Water