title: Pulmonary thrombembolism as cause of death on unenhanced postmortem 3T MRI.
abstract: OBJECTIVE
  To investigate unenhanced postmortem 3-T MR imaging (pmMRI) for the detection of pulmonary thrombembolism (PTE) as cause of death.
  
  
  METHODS
  In eight forensic cases dying from a possible cardiac cause but with homogeneous myocardium at cardiac pmMRI, additional T2w imaging of the pulmonary artery was performed before forensic autopsy. Imaging was carried out on a 3-T MR system in the axial and main pulmonary artery adapted oblique orientation in situ. In three cases axial T2w pmMRI of the lower legs was added. Validation of imaging findings was performed during forensic autopsy.
  
  
  RESULTS
  All eight cases showed homogeneous material of intermediate signal intensity within the main pulmonary artery and/or pulmonary artery branches. Autopsy confirmed the MR findings as pulmonary artery thrombembolism. At lower leg imaging unilateral dilated veins and subcutaneous oedema with or without homogeneous material of intermediate signal intensity within the popliteal vein were found.
  
  
  CONCLUSIONS
  Unenhanced pmMRI demonstrates pulmonary thrombembolism in situ. PmMR may serve as an alternative to clinical autopsy, especially when consent cannot be obtained.
  
  
  CONCLUSIONS
  • Postmortem MRI (pmMRI) provides an alternative to clinical autopsy • Fatal pulmonary thrombembolism (PTE) can now be diagnosed using postmortem MRI (pmMRI). • Special attention has to be drawn to the differentiation of postmortem clots.
authors.affiliation: Forensic Imaging Center Bern, Institute of Forensic Medicine, University of Bern, Buehlstr. 20, 3012 Bern, Switzerland. christian.jackowski@irm.unibe.ch
authors.forename: Christian
authors.initials: C
authors.lastname: Jackowski
authors.forename: Silke
authors.initials: S
authors.lastname: Grabherr
authors.forename: Nicole
authors.initials: N
authors.lastname: Schwendener
mesh_terms: D001344:Autopsy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000473:pathology*