title: Iridium-catalyzed asymmetric hydroalkynylation reactions of oxabenzonorbornadienes.
abstract: Oxabenzonorbornadienes were found to be suitable substrates for asymmetric hydroalkynylation reactions. Catalyzed by the complex of [Ir(COD)Cl](2) and (R)-SYNPHOS, oxabenzonorbornadienes and terminal alkynes could react smoothly to give the alkynylated products in moderate to good yields (up to 93% yield) and enantioselectivities (up to 85% ee).
authors.affiliation: Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission and Ministry of Education, Yunnan University of Nationalities, Kunming, 650500, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Hu
authors.forename: Qingjing
authors.initials: Q
authors.lastname: Yang
authors.forename: Jianbin
authors.initials: J
authors.lastname: Xu
authors.forename: Chao
authors.initials: C
authors.lastname: Huang
authors.forename: Baomin
authors.initials: B
authors.lastname: Fan
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.forename: Chengyuan
authors.initials: C
authors.lastname: Lin
authors.forename: Zhaoxiang
authors.initials: Z
authors.lastname: Bian
authors.forename: Albert S C
authors.initials: AS
authors.lastname: Chan
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D007495:Iridium / Q000737:chemistry*; D009636:Norbornanes / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: C545416:7-oxabenzonorbornadiene; D000480:Alkynes; D009636:Norbornanes; D007495:Iridium