title: Cadaveric and in vivo human joint imaging based on differential phase contrast by X-ray Talbot-Lau interferometry.
abstract: We developed an X-ray phase imaging system based on Talbot-Lau interferometry and studied its feasibility for clinical diagnoses of joint diseases. The system consists of three X-ray gratings, a conventional X-ray tube, an object holder, an X-ray image sensor, and a computer for image processing. The joints of human cadavers and healthy volunteers were imaged, and the results indicated sufficient sensitivity to cartilage, suggesting medical significance.
authors.affiliation: Department of Radiology, Saitama Medical University, 38 Morohongo, Moroyama, Iruma, Saitama 350-0495, Japan. jtanaka@saitama-med.ac.jp
authors.forename: Junji
authors.initials: J
authors.lastname: Tanaka
authors.forename: Masabumi
authors.initials: M
authors.lastname: Nagashima
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Kido
authors.forename: Yoshihide
authors.initials: Y
authors.lastname: Hoshino
authors.forename: Junko
authors.initials: J
authors.lastname: Kiyohara
authors.forename: Chiho
authors.initials: C
authors.lastname: Makifuchi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Nishino
authors.forename: Sumiya
authors.initials: S
authors.lastname: Nagatsuka
authors.forename: Atsushi
authors.initials: A
authors.lastname: Momose
mesh_terms: D001175:Arthrography / Q000295:instrumentation*; D002102:Cadaver; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005240:Feasibility Studies; D005384:Finger Joint / Q000000981:diagnostic imaging*; D006801:Humans; D007368:Interferometry / Q000295:instrumentation*; D012031:Refractometry / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000295:instrumentation*; D014961:X-Ray Diffraction / Q000295:instrumentation*