title: [Advance in studies on pharmacological effect of salidroside on nervous system diseases].
abstract: Salidroside is an extract from Rhodiola crenulata as well as one of major active constituents. In studies of recent years, salidroside showed multiple effects in protecting nerves, scavenging free radicals, regulating central nervous system neurotransmitter, increasing the ability to promote nerve repair and modulating of apoptosis-related gene expression. Hence, it is expected to be applied in treating degenerative nerve diseases and brain ischemic diseases. This essay summarizes studies on pharmacological effects of salidroside on nerve system diseases, providing reference for further studies, development and application of R. crenulata.
authors.affiliation: Clifford Hospital, Guangzhou University of Chinese Medicine, Guangzhou 511495, China. xiehui@sina.cn
authors.forename: Hui
authors.initials: H
authors.lastname: Xie
authors.forename: Da-hui
authors.initials: DH
authors.lastname: Zhu
mesh_terms: D000818:Animals; D051017:Apoptosis Regulatory Proteins / Q000235:genetics / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005960:Glucosides / Q000494:pharmacology*; D006801:Humans; D009422:Nervous System Diseases / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism; D010636:Phenols / Q000494:pharmacology*; D029771:Rhodiola / Q000737:chemistry*
chemical_list: D051017:Apoptosis Regulatory Proteins; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D010636:Phenols; C009172:rhodioloside