title: Model for human milk fat substitute evaluation based on triacylglycerol composition profile.
abstract: Being the dominant components in human milk fat (HMF), triacylglycerol (TAG) composition might be the best approximation index to represent the composing characteristics of HMF. In this study, TAG composition of HMF from different lactation stages was analyzed by RP-HPLC-APCI-MS, and the establishment of a model for the precise evaluation of human milk fat substitutes (HMFSs) based on TAG composition was indirectly realized by employment of fatty acid composition and distribution and polyunsaturated fatty acid (PUFA) and TAG compositions. The model was verified by the selected fats and oils with specific chemical compositions, and the results revealed the degrees of similarity of these fats and oils in different evaluation aspects reflected their differences in corresponding chemical composition with HMF. The newly established evaluation model with TAG composition as a comparison base could provide a more accurate method to evaluate HMFSs and might have some inspirations for HMFS production in the future.
authors.affiliation: State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, Jiangsu, People's Republic of China.
authors.forename: Xiao-Qiang
authors.initials: XQ
authors.lastname: Zou
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Huang
authors.forename: Qing-Zhe
authors.initials: QZ
authors.lastname: Jin
authors.forename: Zheng
authors.initials: Z
authors.lastname: Guo
authors.forename: Yuan-Fa
authors.initials: YF
authors.lastname: Liu
authors.forename: Ling-Zhi
authors.initials: LZ
authors.lastname: Cheong
authors.forename: Xue-Bing
authors.initials: XB
authors.lastname: Xu
authors.forename: Xing-Guo
authors.initials: XG
authors.lastname: Wang
mesh_terms: D002851:Chromatography, High Pressure Liquid; D019358:Fat Substitutes / Q000032:analysis*; D005231:Fatty Acids, Unsaturated / Q000378:metabolism; D006801:Humans; D013058:Mass Spectrometry; D008895:Milk, Human / Q000737:chemistry*; D008956:Models, Chemical; D014280:Triglycerides / Q000737:chemistry* / Q000378:metabolism
chemical_list: D019358:Fat Substitutes; D005231:Fatty Acids, Unsaturated; D014280:Triglycerides