title: [Profile of proinflammatory cytokines in type 1 diabetes mellitus].
abstract: The study involved 70 patients with type 1 diabetes who were under medical care in the clinical city hospital. Patients were divided into two groups: group I included patients with severe form of diabetes with complications and group II included patients without complications. The cytokine profile in the diabetes mellitus patients was investigated. The study showed that all indices of proinflammatory cytokines in patients of both groups were higher than in control healthy subjects. The positive correlation between the level of proinflammatory cytokines in blood and severity of the course of disease was revealed.
authors.forename: Iu H
authors.initials: IuH
authors.lastname: Kyiak
authors.forename: N V
authors.initials: NV
authors.lastname: Fartushok
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Onyshchuk
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Fedevych
authors.forename: H V
authors.initials: HV
authors.lastname: Bashta
mesh_terms: D016022:Case-Control Studies; D048909:Diabetes Complications; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000276:immunology / Q000503:physiopathology; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D053583:Interleukin-1beta / Q000097:blood / Q000276:immunology; D015850:Interleukin-6 / Q000097:blood / Q000276:immunology; D016209:Interleukin-8 / Q000097:blood / Q000276:immunology; D008297:Male; D008875:Middle Aged; D047888:Receptors, Tumor Necrosis Factor, Type I / Q000097:blood / Q000276:immunology; D012720:Severity of Illness Index; D058408:Th1-Th2 Balance; D014409:Tumor Necrosis Factor-alpha / Q000097:blood / Q000276:immunology
chemical_list: C508606:CXCL8 protein, human; C508600:IL6 protein, human; D053583:Interleukin-1beta; D015850:Interleukin-6; D016209:Interleukin-8; D047888:Receptors, Tumor Necrosis Factor, Type I; D014409:Tumor Necrosis Factor-alpha