title: Red cell distribution width is associated with acute myocardial infarction in young patients.
abstract: BACKGROUND
  There are few studies about predictors of ST elevation myocardial infarction (STEMI) in young patients. High red cell distribution width (RDW) levels were associated with adverse outcomes in patients with STEMI. We aimed to investigate the relationship between RDW and STEMI in young patients.
  
  
  METHODS
  This study included 370 patients who presented to our hospital with acute myocardial infarction (Group 1: 198 young patients, 〈 45 ages for male, 〈 55 ages for female, Group 2: 172 elderly patients) and 156 adults with normal coronary angiography as a control group (Group 3: 91 young patients, 〈 45 ages for male, 〈 55 ages for female, Group 4: 65 elderly patients).
  
  
  RESULTS
  Compared with Group 3, Group 1 had a significantly higher value of RDW (Group 1 RDW 14.1 ± 1.1%, Group 3 RDW 13.4 ± 0.9, p1 〈 0.01). Value of RDW was similar both of Group 2 and 4 (Group 2 RDW 13.7 ± 1.2, Group 4 RDW 13.5 ± 0.9, p2 = 0.1). After multivariate analysis, high levels of RDW were independent predictors of STEMI in young patients (OR: 0.337, p 〈 0.01) together with gender (OR: 3.725, p 〈 0.01), history of hyperlipidemia (OR: 25.172, p 〈 0.01) and high density lipoprotein cholesterol (OR: 1.088, p 〈 0.01).
  
  
  CONCLUSIONS
  High levels of RDW were associated with STEMI in young patients. We think that RDW is a widely available marker with no additional costs, in contrast to other novel markers of cardiovascular risk.
authors.affiliation: Department of Cardiology, Kayseri Education and Research Hospital, Kayseri, Turkey. onurkadir@gmail.com
authors.forename: Onur Kadir
authors.initials: OK
authors.lastname: Uysal
authors.forename: Mustafa
authors.initials: M
authors.lastname: Duran
authors.forename: Bugra
authors.initials: B
authors.lastname: Ozkan
authors.forename: Durmus Yildiray
authors.initials: DY
authors.lastname: Sahin
authors.forename: Kamuran
authors.initials: K
authors.lastname: Tekin
authors.forename: Zafer
authors.initials: Z
authors.lastname: Elbasan
authors.forename: Fatih
authors.initials: F
authors.lastname: Akin
authors.forename: Mehmet
authors.initials: M
authors.lastname: Balli
authors.forename: Ozgur
authors.initials: O
authors.lastname: Gunebakmaz
authors.forename: Huseyin
authors.initials: H
authors.lastname: Arinc
authors.forename: Mehmet Gungor
authors.initials: MG
authors.lastname: Kaya
authors.forename: Murat
authors.initials: M
authors.lastname: Cayli
mesh_terms: D000328:Adult; D000465:Algorithms; D016022:Case-Control Studies; D017023:Coronary Angiography; D004909:Erythrocyte Indices; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000097:blood* / Q000175:diagnosis*; D011237:Predictive Value of Tests; D012307:Risk Factors; D012680:Sensitivity and Specificity