title: Utf1: Goldilocks for ESC bivalency.
abstract: Recently in Cell, Jia et al. (2012) reported novel Utf1-controlled mechanisms of maintaining pluripotency and self-renewal in embryonic stem cells (ESCs). Utf1 buffers bivalent gene expression by competitive binding with polycomb repressive complex 2 and initiation of mRNA degradation.
authors.affiliation: Department of Cell Biology and Human Anatomy, University of California Davis School of Medicine, Sacramento, CA 95817, USA.
authors.forename: Agnieszka I
authors.initials: AI
authors.lastname: Laskowski
authors.forename: Paul S
authors.initials: PS
authors.lastname: Knoepfler