title: Refractory giardiasis in Spanish travellers.
abstract: Drug failure is a common cause of symptom persistence after treatment of imported Giardia duodenalis. In this retrospective study we describe a high prevalence of refractory giardiasis in people attended in a travel clinic in Spain, especially those with infections acquired in Asia. Moreover, we discuss various treatment strategies to tackle G. duodenalis that is refractory to nitroimidazoles.
authors.affiliation: Barcelona Centre for International Health Research (CRESIB, Hospital Clínic-Universitat de Barcelona), Barcelona, Spain. jmunozg@clinic.ub.es
authors.forename: Jose
authors.initials: J
authors.lastname: Muñoz Gutiérrez
authors.forename: Edelweiss
authors.initials: E
authors.lastname: Aldasoro
authors.forename: Ana
authors.initials: A
authors.lastname: Requena
authors.forename: Ana M
authors.initials: AM
authors.lastname: Comin
authors.forename: Maria Jesús
authors.initials: MJ
authors.lastname: Pinazo
authors.forename: Azucena
authors.initials: A
authors.lastname: Bardají
authors.forename: Inés
authors.initials: I
authors.lastname: Oliveira
authors.forename: Maria Eugenia
authors.initials: ME
authors.lastname: Valls
authors.forename: Joaquim
authors.initials: J
authors.lastname: Gascon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000465:Algorithms; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D005243:Feces / Q000469:parasitology; D005260:Female; D016829:Giardia lamblia / Q000302:isolation & purification*; D005873:Giardiasis / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009593:Nitroimidazoles / Q000627:therapeutic use; D012189:Retrospective Studies; D013030:Spain / Q000453:epidemiology; D014195:Travel; D017211:Treatment Failure
chemical_list: D000981:Antiprotozoal Agents; D009593:Nitroimidazoles