title: Comb-like ionic complexes of hyaluronic acid with alkyltrimethylammonium surfactants.
abstract: Stoichiometric complexes of hyaluronic acid with alkyltrimethylammonium surfactants bearing octadecyl, eicosyl and docosyl groups were prepared by ionic coupling in aqueous solution. The complexes were non soluble in water but soluble in organic solvents. In the solid state they self-assembled in a biphasic layered structure with the alkyl side chains forming a separate phase that melted in the 50-60 °C range. They were stable to heating up to above 200 °C.
authors.affiliation: Department d'Enginyeria Química, Universitat Politècnica de Catalunya, ETSEIB, Diagonal 647, Barcelona 08028, Spain.
authors.forename: Ainhoa
authors.initials: A
authors.lastname: Tolentino
authors.forename: Abdelilah
authors.initials: A
authors.lastname: Alla
authors.forename: Antxon
authors.initials: A
authors.lastname: Martínez de Ilarduya
authors.forename: Sebastián
authors.initials: S
authors.lastname: Muñoz-Guerra
mesh_terms: D006820:Hyaluronic Acid / Q000737:chemistry*; D052578:Ionic Liquids / Q000737:chemistry; D011108:Polymers / Q000737:chemistry; D012997:Solvents; D013501:Surface-Active Agents / Q000737:chemistry*; D050337:Trimethyl Ammonium Compounds / Q000737:chemistry*; D014574:Uronic Acids / Q000737:chemistry; D014867:Water / Q000737:chemistry
chemical_list: D052578:Ionic Liquids; D011108:Polymers; D012997:Solvents; D013501:Surface-Active Agents; D050337:Trimethyl Ammonium Compounds; D014574:Uronic Acids; C018402:traumacel; D014867:Water; D006820:Hyaluronic Acid