title: Inapparent infection during an outbreak of dengue fever in Southeastern China.
abstract: Dengue fever (DF) is often asymptomatic in endemic areas. Asymptomatic infection during a DF outbreak in China, where DF is not endemic, has not been reported until now. In this study a total of 365 subjects from 6 villages were recruited from October 4-7, 2009. Overall, 102 subjects (27.95%) were positive for dengue virus (DENV) IgM, and 14 subjects (3.84%) were positive for DENV IgG and IgM. In different age groups, seropositive rates varied from 12.50% to 50.00% for DENV IgM, and from 0% to 11.76% for DENV IgG. Seroprevalence of DENV IgM was significantly higher than that of DENV IgG. Seroprevalence rates of DENV IgM differed among different villages. However, the seroprevalence of DENV IgM was not statistically significantly different among gender and age groups. Asymptomatic DF infection is prevalent in non-endemic areas.
authors.affiliation: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China.
authors.forename: Jimin
authors.initials: J
authors.lastname: Sun
authors.forename: Shuying
authors.initials: S
authors.lastname: Luo
authors.forename: Junfen
authors.initials: J
authors.lastname: Lin
authors.forename: Jinhua
authors.initials: J
authors.lastname: Chen
authors.forename: Juan
authors.initials: J
authors.lastname: Hou
authors.forename: Tao
authors.initials: T
authors.lastname: Fu
authors.forename: Huakun
authors.initials: H
authors.lastname: Lv
authors.forename: Zhiping
authors.initials: Z
authors.lastname: Chen
authors.forename: Liming
authors.initials: L
authors.lastname: Cong
authors.forename: Feng
authors.initials: F
authors.lastname: Ling
authors.forename: Chengliang
authors.initials: C
authors.lastname: Chai
authors.forename: Yanjun
authors.initials: Y
authors.lastname: Zhang
authors.forename: Haiyan
authors.initials: H
authors.lastname: Mao
authors.forename: Juying
authors.initials: J
authors.lastname: Yan
authors.forename: Yiyu
authors.initials: Y
authors.lastname: Lu
authors.forename: Qiyong
authors.initials: Q
authors.lastname: Liu
authors.forename: Xiuping
authors.initials: X
authors.lastname: Song
authors.forename: Liang
authors.initials: L
authors.lastname: Lu
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000914:Antibodies, Viral / Q000097:blood*; D058070:Asymptomatic Diseases / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D003715:Dengue / Q000453:epidemiology*; D003716:Dengue Virus / Q000276:immunology*; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D019371:Topography, Medical; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M