title: [Enlargement of intrathoracic diffuse large B-cell lymphoma during treatment of pulmonary tuberculosis: a case report].
abstract: We described enlargement of intrathoracic diffuse large B-cell lymphoma (DLBCL) during treatment of pulmonary tuberculosis in a 78-year-old man. The patient had previously undergone treatment for pulmonary tuberculosis about 50 years ago and showed disease recurrence in 2010. Although after tuberculosis treatment with the standard chemotherapy regimen of isoniazid, rifampicin, ethambutol, and pyrazinamide, we observed a clear resolution of the main X-ray shadows, a nodular shadow in the right upper lung field was observed to have increased in size. After evaluation by transbronchial biopsy of the upper right lung lobe, we diagnosed DLBCL with subepithelial infiltration of an airway. This is a rare case of coexistence of active pulmonary tuberculosis and intrathoracic DLBCL.
authors.affiliation: Department of Respiratory Medicine, National Hospital Organization Kinki-chuo Chest Medical Center, Osaka, Japan.
authors.forename: Shojiro
authors.initials: S
authors.lastname: Minomo
authors.forename: Kazunobu
authors.initials: K
authors.lastname: Tachibana
authors.forename: Taisuke
authors.initials: T
authors.lastname: Tsuji
authors.forename: Kazunari
authors.initials: K
authors.lastname: Tsuyuguchi
authors.forename: Masanori
authors.initials: M
authors.lastname: Kitaichi
authors.forename: Seiji
authors.initials: S
authors.lastname: Hayashi
authors.forename: Katsuhiro
authors.initials: K
authors.lastname: Suzuki
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology*; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000188:drug therapy
chemical_list: D000970:Antineoplastic Agents