title: Identification and characterization of a novel subgenotype of bovine viral diarrhea virus isolated from dairy cattle in Northwestern China.
abstract: Bovine viral diarrhea virus (BVDV) was detected by RT-PCR in 105 out of 391 samples which were collected from five dairy farms in Ningxia, China during 2010-2011. Non-cytopathogenic BVDV was isolated from 13 samples and a 230-bp fragment of the 5'-untranslated region was amplified and sequenced. While the predominant subgenotypes were BVDV-1b and BVDV-1d, a potentially novel subgenotype was identified by phylogenetic analysis, which may have implications for vaccine development.
authors.affiliation: State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Public Health of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 1 Xujiaping, Chengguan, Lanzhou 730046, People's Republic of China.
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Gong
authors.forename: Xiaoan
authors.initials: X
authors.lastname: Cao
authors.forename: Fuying
authors.initials: F
authors.lastname: Zheng
authors.forename: Qiwei
authors.initials: Q
authors.lastname: Chen
authors.forename: Jizhang
authors.initials: J
authors.lastname: Zhou
authors.forename: Hong
authors.initials: H
authors.lastname: Yin
authors.forename: Lihong
authors.initials: L
authors.lastname: Liu
authors.forename: Xuepeng
authors.initials: X
authors.lastname: Cai
mesh_terms: D000818:Animals; D001912:Bovine Virus Diarrhea-Mucosal Disease / Q000453:epidemiology / Q000821:virology*; D002417:Cattle; D002681:China / Q000453:epidemiology; D001908:Diarrhea Viruses, Bovine Viral / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D014644:Genetic Variation; D008969:Molecular Sequence Data; D010802:Phylogeny