title: Lichen planus-like lesions as the first manifestation of adult T-cell leukaemia/lymphoma.
abstract: Cutaneous involvement is frequent in adult T-cell leukaemia/lymphoma (ATLL), a peripheral T-cell neoplasm caused by human T-cell lymphotropic virus type I (HTLV-I). Patients with ATLL manifest different types of skin lesions, including nodules, plaques, ulcers, erythroderma and purpura. It has been reported that this type of skin eruption is an independent prognostic factor for ATLL. We report here a rare case of a 62-year-old Japanese woman with smouldering-type ATLL, first manifested by lichen planus-like skin lesions on the lower leg. This case report highlights the multiplicity of skin manifestations in ATLL.
authors.affiliation: Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: Hayakazu
authors.initials: H
authors.lastname: Sumida
authors.forename: Makoto
authors.initials: M
authors.lastname: Sugaya
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kamata
authors.forename: Hiraku
authors.initials: H
authors.lastname: Suga
authors.forename: Tomomitsu
authors.initials: T
authors.lastname: Miyagaki
authors.forename: Hanako
authors.initials: H
authors.lastname: Ohmatsu
authors.forename: Hideki
authors.initials: H
authors.lastname: Fujita
authors.forename: Shinichi
authors.initials: S
authors.lastname: Sato
mesh_terms: D015703:Antigens, CD / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D015368:Human T-lymphotropic virus 1 / Q000235:genetics; D006801:Humans; D007150:Immunohistochemistry; D007866:Leg; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000150:complications / Q000276:immunology / Q000473:pathology* / Q000628:therapy / Q000821:virology; D008010:Lichen Planus / Q000209:etiology / Q000276:immunology / Q000473:pathology* / Q000628:therapy / Q000821:virology; D008875:Middle Aged; D012867:Skin / Q000276:immunology / Q000473:pathology* / Q000821:virology
chemical_list: D015703:Antigens, CD; D014408:Biomarkers, Tumor; D004279:DNA, Viral