title: Triglyceride and non-high-density lipoprotein cholesterol as predictors of cardiovascular disease risk factors in Chinese Han children.
abstract: OBJECTIVE
  To investigate the role of serum cholesterol and triglyceride in the assessment of cardiovascular disease risk factors in children and adolescents.
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  Childrens Hospital of Zhejiang University School of Medicine, Hangzhou, China.
  
  
  METHODS
  Children from 6 years to 17 year old. 188 with simple obesity, and 431 with obesity and metabolic abnormalities. 274 age and gender-matched healthy children as controls.
  
  
  METHODS
  Receiver operating characteristic curves were used to analyze the detection of cardiovascular disease risk factors by cholesterol and triglyceride in children and adolescents.
  
  
  RESULTS
  The ranges of areas under receiver operating characteristic curves (AUC) for triglyceride and non-high-density lipoprotein cholesterol were 0.798-0.860 and 0.667-0.749, respectively to detect cardiovascular disease risk factors. The ranges of AUC for low-density lipoprotein cholesterol, total cholesterol, and high-density lipoprotein cholesterol were 0.631-0.718, 0.596-0.683, and 0.292-0.376, respectively.
  
  
  CONCLUSIONS
  Triglyceride and non-high-density lipoprotein cholesterol are better than low-density lipoprotein cholesterol as predictors of cardiovascular disease risk factors in Chinese Han children and adolescents.
authors.affiliation: Department of Endocrinology, Childrens Hospital of Zhejiang University School of Medicine, Hangzhou, China.
authors.forename: Wei Fen
authors.initials: WF
authors.lastname: Zhu
authors.forename: Li
authors.initials: L
authors.lastname: Liang
authors.forename: Chun Lin
authors.initials: CL
authors.lastname: Wang
authors.forename: Jun Fen
authors.initials: JF
authors.lastname: Fu
mesh_terms: D000293:Adolescent; D019540:Area Under Curve; D044466:Asian People; D002318:Cardiovascular Diseases / Q000097:blood* / Q000453:epidemiology; D016022:Case-Control Studies; D002648:Child; D002681:China / Q000453:epidemiology; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000453:epidemiology; D008297:Male; D024821:Metabolic Syndrome / Q000097:blood / Q000453:epidemiology; D009765:Obesity / Q000097:blood / Q000453:epidemiology; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood*
chemical_list: D008076:Cholesterol, HDL; D014280:Triglycerides; D002784:Cholesterol