title: [The treatment of the patients presenting with chronic inflammation of the trepanation cavity with a preparation containing silver nanoparticles following sanitation surgery of the open type].
abstract: The objective of the present study was to estimate the efficacy of argovit used for the treatment of relapses of chronic suppurative otitis medium (CSOM) developing in the patients who underwent the sanitation surgical procedure. The study carried out between January 2011 and November 2011 included 35 patients aged from 12 to 69 years presenting with CSOM after surgical intervention on the tympanic cavity of the middle ear. The treatment resulted in the rapid elimination of clinical symptoms and positive dynamics of the objective signs of the disease, such as reduction or termination of pathological exudation and stimulation of the epidermization processes. The majority of the treated patients had stable remission within 6 months after the termination of the treatment.
authors.forename: F V
authors.initials: FV
authors.lastname: Semenov
authors.forename: K M
authors.initials: KM
authors.lastname: Fidarova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002908:Chronic Disease; D004432:Ear, Middle / Q000187:drug effects / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D053758:Nanoparticles / Q000008:administration & dosage*; D010035:Otitis Media, Suppurative / Q000601:surgery / Q000628:therapy*; D012189:Retrospective Studies; D012834:Silver / Q000008:administration & dosage*; D014207:Trephining / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D012834:Silver