title: [A case of liver metastases from gastric cancer successfully treated with weekly paclitaxel chemotherapy].
abstract: A 63-year-old woman underwent distal gastrectomy for gastric cancer (P+, CY+, Stage IV) in February 2011. About 3 months after surgery, abdominal computed tomography(CT) examination revealed solitary liver metastasis. Systemic chemotherapy was started using a regimen of S-1/cisplatin(CDDP). After 2 courses, an adverse reaction of grade 3 neutropenia occurred, although liver metastasis regression was confirmed. Weekly paclitaxel (PTX)was selected as the second -line chemotherapy. After 3 courses, imaging indicated complete regression of the liver metastasis. No adverse events occurred following 5 courses of weekly PTX. No recurrence was noted at a post-surgical follow-up of 15 months. We experienced a case of liver metastasis that was successfully treated with S-1/CDDP and weekly PTX chemotherapy.
authors.affiliation: Dept. of Surgery, Suita Municipal Hospital, Japan.
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Okada
authors.forename: Chikara
authors.initials: C
authors.lastname: Ebisui
authors.forename: Masahiro
authors.initials: M
authors.lastname: Murakami
authors.forename: Tetsu
authors.initials: T
authors.lastname: Yanagisawa
authors.forename: Shu
authors.initials: S
authors.lastname: Okamura
authors.forename: Kohei
authors.initials: K
authors.lastname: Murata
authors.forename: Hideoki
authors.initials: H
authors.lastname: Yokouchi
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Tamai
authors.forename: Masakatsu
authors.initials: M
authors.lastname: Kinuta
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D017239:Paclitaxel