title: Influence of Maillard products from bread crust on magnesium bioavailability in rats.
abstract: BACKGROUND
  Consumption of Maillard reaction products (MRPs) present in food has been related to deterioration of protein digestibility and changes in mineral bioavailability. We aimed to investigate the effects of MRP intake from bread crust on magnesium balance and tissue distribution, seeking causative factors among its different components.
  
  
  RESULTS
  During the final stage of the trial, magnesium digestibility improved by around 15% in rats fed diets containing bread crust or its derivatives compared with the control diet. Despite certain enhancements in magnesium bioavailability in this stage, for the experimental period as a whole, this parameter remained unchanged. However, specific changes in the content and/or concentration in some organs were observed, particularly in the femur, where magnesium levels were higher due to the smaller size of the bones.
  
  
  CONCLUSIONS
  Consumption of MRPs from bread crust or its different components did not modify the magnesium balance. Nevertheless, the bread crust fractions led to some changes in magnesium tissue distribution which did not match the effects induced by complete bread crust intake, suggesting the importance of designing studies with real-food systems, in order to reinforce the validity of the findings obtained.
authors.affiliation: Instituto en Formación de Nutrición Animal, Estación Experimental del Zaidín, CSIC, 18100, Granada, Spain.
authors.forename: Irene
authors.initials: I
authors.lastname: Roncero-Ramos
authors.forename: Cristina
authors.initials: C
authors.lastname: Delgado-Andrade
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Morales
authors.forename: María Pilar
authors.initials: MP
authors.lastname: Navarro
mesh_terms: D000821:Animal Feed; D000818:Animals; D001682:Biological Availability; D001939:Bread / Q000032:analysis*; D004032:Diet; D008274:Magnesium / Q000493:pharmacokinetics*; D015416:Maillard Reaction; D011897:Random Allocation; D051381:Rats
chemical_list: D008274:Magnesium