title: Recurrence-free and 5-year survival following robotic-assisted surgical staging for endometrial carcinoma.
abstract: OBJECTIVE
  The aim of this study is to report recurrence-free and overall survival for women with endometrial adenocarcinoma who were surgically staged using robotic-assisted laparoscopy.
  
  
  METHODS
  A retrospective chart review was performed for all consecutive endometrial adenocarcinoma patients surgically staged with robotic-assisted laparoscopy at the University of North Carolina Hospital from 2005 to 2010. Demographic data, 5-year survival, and recurrence-free intervals were analyzed. Statistical analysis using Chi-square, t-test, and Kaplan-Meier curves were performed with SAS software. Study results were compared to endometrial cancer statistics from the Surveillance Epidemiology and End Results database from the National Cancer Institute.
  
  
  RESULTS
  A total of 499 patients were identified and included in the study. Recurrence-free intervals after robotic-assisted surgical staging were 85.2% for stage IA, 80.2% for stage IB, 69.8% for stage II, and 69% for stage III. Projected 5-year survival was 88.7% for all patients included in the study. Nearly 82% of cases were endometrioid adenocarcinoma, with papillary serous, clear cell or mixed histology comprising 17.4% of cases. Median follow up time was 23 months, with a range of 0 to 80 months. Among stage IA, IB, II, and III patients, projected overall survival was 94.2%, 85.9%, 77.4%, and 68.6%, respectively.
  
  
  CONCLUSIONS
  The results from this study demonstrate that robotic-assisted surgical staging for endometrial cancer does not adversely affect rates of recurrence or survival. These findings provide further evidence that robotic-assisted laparoscopic surgical staging is not associated with inferior results when compared to laparotomy or traditional laparoscopy.
authors.affiliation: Division of Gynecologic Oncology, University of North Carolina, Chapel Hill, NC, USA. jekilg@gmail.com
authors.forename: Joshua E
authors.initials: JE
authors.lastname: Kilgore
authors.forename: Amanda L
authors.initials: AL
authors.lastname: Jackson
authors.forename: Emily M
authors.initials: EM
authors.lastname: Ko
authors.forename: John T
authors.initials: JT
authors.lastname: Soper
authors.forename: Linda
authors.initials: L
authors.lastname: Van Le
authors.forename: Paola A
authors.initials: PA
authors.lastname: Gehrig
authors.forename: John F
authors.initials: JF
authors.lastname: Boggess
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016889:Endometrial Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D012189:Retrospective Studies; D012371:Robotics / Q000379:methods*; D013997:Time Factors