title: Effective bacterial inactivation and removal of copper by porous ceramics with high surface area.
abstract: In this study, we present porous ceramics combining the antibacterial effect of copper with an integrated copper removal adsorbent. After preparing and characterizing the antibacterial copper-doped microbeads and monoliths (CuBs and CuMs), their antibacterial efficiency is probed against different nonpathogenic and pathogenic bacteria (Bacillus subtilis, Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa). An antibacterial efficiency of 100% is reached within 15 min to 3 h for all tested strains under static conditions. Dynamic tests with B. subtilis and E. coli showed high antibacterial efficiency up to 99.93% even at continuous flux. To avoid any adverse effects on the environment, continuous removal of released copper-ions is accomplished with porous, high surface area monolithic adsorbents (MAds). MAds are prepared similarly to the CuMs but without adding copper during the manufacturing process. MAds reduce the amount of copper released from the CuMs ≥ 99% during the first 15 min, ≥90% up to 2 h, and after 22 h of continuous filtration up to 56% of the released copper is removed.
authors.affiliation: Advanced Ceramics, University of Bremen, Germany.
authors.forename: Tanja Yvonne
authors.initials: TY
authors.lastname: Klein
authors.forename: Julia
authors.initials: J
authors.lastname: Wehling
authors.forename: Laura
authors.initials: L
authors.lastname: Treccani
authors.forename: Kurosch
authors.initials: K
authors.lastname: Rezwan
mesh_terms: D000327:Adsorption; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects; D001424:Bacterial Infections / Q000517:prevention & control; D002516:Ceramics / Q000737:chemistry*; D003300:Copper / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D008826:Microbial Sensitivity Tests; D016062:Porosity; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D014871:Water Microbiology; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D014874:Water Pollutants, Chemical; D003300:Copper