title: Design of clinical studies: adaptive randomization and progression-free survival (PFS) as an endpoint in clinical studies of advanced non-small cell lung cancer (NSCLC).
authors.affiliation: Deutsches Krebsforschungszentrum (DKFZ), Department of Biostatistics, Heidelberg, Germany. d.schrimpf@dkfz.de
authors.forename: Daniel
authors.initials: D
authors.lastname: Schrimpf
authors.forename: Christian
authors.initials: C
authors.lastname: Manegold
authors.forename: Lothar R
authors.initials: LR
authors.lastname: Pilz
mesh_terms: D001499:Bayes Theorem; D002289:Carcinoma, Non-Small-Cell Lung / Q000453:epidemiology* / Q000628:therapy*; D018572:Disease-Free Survival; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000628:therapy*; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic / Q000379:methods*; D012107:Research Design; D018401:Sample Size