title: Genetic variation between two Tibetan macaque (Macaca thibetana) populations in the eastern China based on mitochondrial DNA control region sequences.
abstract: Tibetan macaque (Macaca thibetana) is a threatened primate species endemic to China. Population genetic and phylogenetic analyses were conducted in 66 Tibetan individuals from Sichuan (SC), Huangshan (HS), and Fujian (FJ) based on a 477-bp fragment of mitochondrial DNA control region. Four new haplotypes were defined, and a relatively high level of genetic diversity was first observed in FJ populations (Hd = 0.7661). Notably, a continuous approximately 10 bp-fragment deletion was observed near the 5' end of the mtDNA control region of both HS and FJ populations when compared with that of SC population, and a sharing haplotype was found between the two populations, revealing a closer genetic relationship. However, significant genetic differentiation (FST = 0.8700) and more poor gene exchange (Nm < 1) had occurred among three populations. This study mainly provide a further insight into the genetic relationship between HS and FJ Tibetan macaque populations, but it may be necessary to carry out further study with extra samples from other locations in the geographic coverage of the two subspecies (M. thibetana pullus and M. thibetana huangshanensis).
authors.affiliation: College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, China.
authors.forename: Yongfang
authors.initials: Y
authors.lastname: Yao
authors.forename: Lijing
authors.initials: L
authors.lastname: Zhong
authors.forename: Bofeng
authors.initials: B
authors.lastname: Liu
authors.forename: Jiayi
authors.initials: J
authors.lastname: Li
authors.forename: Qingyong
authors.initials: Q
authors.lastname: Ni
authors.forename: Huailiang
authors.initials: H
authors.lastname: Xu
mesh_terms: D000818:Animals; D001483:Base Sequence; D002681:China; D017931:DNA Primers; D004272:DNA, Mitochondrial / Q000235:genetics*; D014644:Genetic Variation; D006239:Haplotypes; D008251:Macaca / Q000145:classification / Q000235:genetics*; D016133:Polymerase Chain Reaction; D012689:Sequence Homology, Nucleic Acid
chemical_list: D017931:DNA Primers; D004272:DNA, Mitochondrial