title: Mood, anxiety and personality disorders in patients with systemic lupus erythematosus.
abstract: OBJECTIVE
  This study presents the current prevalence of mood, anxiety and personality disorders and factors associated with the existence of psychiatric disorders in patients with systemic lupus erythematosus (SLE).
  
  
  METHODS
  The study sample was comprised of 45 patients with SLE and 60 control subjects. Mood and anxiety disorders were ascertained by means of the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition/Clinical Version. Personality disorders were diagnosed with the Structured Clinical Interview for DSM, Revised Third Edition Personality Disorders. The disease activity was assessed with SLE Disease Activity Index.
  
  
  RESULTS
  Of the 45 patients, 21 (46.7%) had at least one mood or anxiety disorder, and 16 (35.6%) had at least one personality disorder. The most common Axis I and Axis II diagnoses in the patient group were major depression (22.2%) and obsessive-compulsive personality disorder (20.0%), respectively. Specifically, major depression, generalized anxiety disorder and obsessive-compulsive personality disorder were more prevalent in the SLE group compared to the control group. The existence of Axis I disorders was associated with a more severe disease activity of SLE.
  
  
  CONCLUSIONS
  Mood and anxiety disorders, particularly major depression and generalized anxiety disorder, are frequently observed in patients with SLE.
authors.affiliation: Department of Psychiatry, University of Necmettin Erbakan, Meram Faculty of Medicine, Konya, Turkey. farukuguz@gmail.com
authors.forename: Faruk
authors.initials: F
authors.lastname: Uguz
authors.forename: Adem
authors.initials: A
authors.lastname: Kucuk
authors.forename: Erdinc
authors.initials: E
authors.lastname: Cicek
authors.forename: Fatih
authors.initials: F
authors.lastname: Kayhan
authors.forename: Recep
authors.initials: R
authors.lastname: Tunc
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000150:complications* / Q000175:diagnosis; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000150:complications* / Q000175:diagnosis; D010554:Personality Disorders / Q000150:complications* / Q000175:diagnosis; D015995:Prevalence