title: Outer eggshell membrane as delivery vehicle for polysaccharide/protein microcapsules incorporated with vitamin E.
abstract: This study investigates the features of a new type of delivery system prepared by combining a natural outer eggshell membrane (OESM) with emulsified microcapsules. The loading efficiency, controlled release properties, and forming mechanisms of the prepared system were studied. The polysaccharide/protein microcapsules incorporated with vitamin E can be attached to highly cross-linked protein fiber networks of OESM. This attachment could be reinforced more than 2-fold using glutaraldehyde as a cross-linking agent. The combined OESM/microcapsule delivery system significantly exhibited better controlled release properties than the microcapsules alone because of the steric blocking effect. Moreover, the OESM delivery system incorporated with microcapsules formed by pectin/protein as wall material showed more resistance against enzymatic attacks because of the formation of compact aggregates promoted by electrostatic effects.
authors.affiliation: CAU and ACC Joint-Laboratory of Space Food, Key Laboratory of Functional Dairy Science of Beijing and Ministry of Education, College of Food Science and Nutritional Engineering, China Agricultural University, Haidian, Beijing, China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Chai
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Li
authors.forename: Fei
authors.initials: F
authors.lastname: Liu
authors.forename: Bingjian
authors.initials: B
authors.lastname: Du
authors.forename: Tong
authors.initials: T
authors.lastname: Jiao
authors.forename: Chunyue
authors.initials: C
authors.lastname: Zhang
authors.forename: Xiaojing
authors.initials: X
authors.lastname: Leng
mesh_terms: D000818:Animals; D002214:Capsules / Q000737:chemistry*; D004337:Drug Carriers / Q000737:chemistry*; D004528:Egg Shell / Q000737:chemistry*; D004655:Emulsions / Q000737:chemistry; D005780:Gelatin / Q000737:chemistry; D005976:Glutaral / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D018613:Microscopy, Confocal; D008855:Microscopy, Electron, Scanning; D008894:Milk Proteins / Q000737:chemistry; D010316:Particle Size; D010368:Pectins / Q000737:chemistry*; D014810:Vitamin E / Q000737:chemistry*; D000067816:Whey Proteins
chemical_list: D002214:Capsules; D004337:Drug Carriers; D004655:Emulsions; D008894:Milk Proteins; D000067816:Whey Proteins; D014810:Vitamin E; D010368:Pectins; D005780:Gelatin; D005976:Glutaral