title: Platelet-rich plasma as a nonsurgical treatment option for osteonecrosis.
abstract: Avascular necrosis (AVN) is a progressive condition characterized by bone tissue cell death as a result of ischemia, which is most often seen in weight-bearing joints. The traditional treatment of this disease process in the hip includes surgical decompression and joint replacement. This case report describes a novel nonsurgical approach for treating advanced-stage degenerative AVN of the hip with the use of autologous platelet-rich plasma. The patient demonstrated significant functional improvements after this intervention without the need for further treatment except for physical therapy. The report suggests the potential utility of platelet-rich plasma for the treatment of degenerative AVN.
authors.affiliation: The Performance and Musculoskeletal Regeneration Center, Washington, DC, USA. DrVictor@PMRCenter.org
authors.forename: Victor
authors.initials: V
authors.lastname: Ibrahim
authors.forename: Heather
authors.initials: H
authors.lastname: Dowling
mesh_terms: D000368:Aged; D016913:Blood Component Transfusion / Q000379:methods*; D005260:Female; D005271:Femur Head Necrosis / Q000175:diagnosis / Q000628:therapy*; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D010020:Osteonecrosis / Q000628:therapy; D026741:Physical Therapy Modalities; D053657:Platelet-Rich Plasma