title: Recovery profile and emergence delirium following sevoflurane and isoflurane anesthesia in children posted for cleft lip surgery.
abstract: This prospective, randomized, double control study was carried out in 84 children aged 2-24 months posted for elective cleft lip surgery.
  
  
  METHODS
  Patients were randomally divided into 2 groups of 42 patients each. In Group A patients were induced and maintained on sevoflurane while in Group B patients were induced with sevoflurane and maintained on isoflurane. Standardized anesthesia technique was used. Recovery milestones and post operative complications were recorded.
  
  
  RESULTS
  Incidence of emergence delirium in sevoflurane group was 11.9% while in isoflurane group is 2.38%. The overall incidence of emergence delirium in the study was 7.14%. There was no significant difference (p > 0.05) in the incidence of emergence delirium between the two groups. There was no effect of duration of exposure of sevoflurane and time taken for achievement of recovery milestones while we observed a positive correlation with isoflurane. In sevoflurane the recovery endpoint first reached was limb movement > spontaneous respiration > spontaneous eye opening. In isoflurane group the recovery end point first reached was spontaneous respiration > limb movement = spontaneous eye opening.
  
  
  CONCLUSIONS
  Our study confirms that the recovery profile of sevoflurane in children less the two years is superior compared to isoflurane.
authors.affiliation: Department of Anaesthesiology, Intensive Care and Pain Management, Himalayan Institute of Medical Sciences, Swami Rama Nagar, Dehradun. parulpjindal@yahoo.co.in
authors.forename: Parul
authors.initials: P
authors.lastname: Jindal
authors.forename: Gurjeet
authors.initials: G
authors.lastname: Khurana
authors.forename: Deepak
authors.initials: D
authors.lastname: Oberoi
authors.forename: Jagdish Prasad
authors.initials: JP
authors.lastname: Sharma
mesh_terms: D000762:Anesthesia Recovery Period; D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D002675:Child, Preschool; D002971:Cleft Lip / Q000601:surgery*; D003693:Delirium / Q000139:chemically induced* / Q000453:epidemiology*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007530:Isoflurane / Q000009:adverse effects*; D008297:Male; D008738:Methyl Ethers / Q000009:adverse effects*; D011446:Prospective Studies; D000077149:Sevoflurane
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D000077149:Sevoflurane; D007530:Isoflurane