title: Behavioral functioning in youth with inflammatory bowel disease: perceived barriers as mediator of medication adherence.
abstract: OBJECTIVE
  To examine the relationship between behavioral functioning specific to levels of attention and conduct problems and prescription medication adherence in youth with inflammatory bowel disease (IBD), and examine the mediational role of perceived barriers to adherence. Identifying potentially malleable factors associated with poor adherence such as behavioral functioning and barriers may guide treatment.
  
  
  METHODS
  85 adolescents with IBD and their parents completed measures of adherence, attention and conduct problems, and barriers. To examine mediation models, indirect effects were tested using bootstrapping procedures outlined by Preacher & Hayes (2004, 2008).
  
  
  RESULTS
  The majority of participants reported normative levels of attention and conduct problems. Higher levels of attention problems, conduct problems, and barriers were negatively associated with adherence. Bootstrapping procedures indicated that barriers mediated the effects of behavioral functioning on adherence.
  
  
  CONCLUSIONS
  Barriers may be a proximal factor contributing to the relationship between everyday behavioral functioning and adherence in youth with IBD.
authors.affiliation: Department of Psychology, University of Georgia, Athens, GA 30602-3013, USA. bonreed@uga.edu
authors.forename: Bonney
authors.initials: B
authors.lastname: Reed-Knight
authors.forename: Jeffery D
authors.initials: JD
authors.lastname: Lewis
authors.forename: Ronald L
authors.initials: RL
authors.lastname: Blount
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior / Q000523:psychology*; D001288:Attention; D002648:Child; D019955:Conduct Disorder / Q000175:diagnosis / Q000523:psychology*; D005260:Female; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy / Q000523:psychology*; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires