title: [A case of recurrent breast cancer in which gemcitabine-docetaxel therapy was successful for a long period].
abstract: This is a case of a 58-year-old woman who underwent mastectomy for advanced right breast cancer (T2N2M0, stage IIIA, ER+, PR+, and HER2 0) at another hospital 13 years ago. Tamoxifen was administered after the operation. Two years later, bone and lung metastases appeared and she was transferred to our hospital. Hormonal therapies, epirubicin- cyclophosphamide-5-FU, doxifluridine, paclitaxel, vinorelbine, and capecitabine were ineffective. We planned a sixth-line chemotherapy comprising gemcitabine combined with docetaxel, but not paclitaxel. Partial response was obtained by treatment with 3 courses of gemcitabine-docetaxel. The same treatment was continued and the patient is alive in a good condition without progression for 14 months.
authors.affiliation: Dept. of Surgery, Tokyo Metropolitan Otsuka Hospital, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Kakimoto
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kawashima
authors.forename: Haruya
authors.initials: H
authors.lastname: Koshiishi
authors.forename: Hiromi
authors.initials: H
authors.lastname: Miyamoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Okamura
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D000077143:Docetaxel; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary; D008875:Middle Aged; D012008:Recurrence; D043823:Taxoids / Q000008:administration & dosage; D013997:Time Factors; D000093542:Gemcitabine
chemical_list: D043823:Taxoids; D003841:Deoxycytidine; D000077143:Docetaxel; D000093542:Gemcitabine