title: Copper-catalyzed aliphatic C-H amination with an amidine moiety.
abstract: A method for amination of aliphatic C-H bonds of N-alkylamidines is described that utilizes Cu(OAc)(2) as the catalyst in the presence of PhI(OAc)(2) and K(3)PO(4). The resulting products, dihydroimidazoles and tetrahydropyrimidines, could be converted into the corresponding diamines by hydride reduction.
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
authors.forename: Stephen
authors.initials: S
authors.lastname: Sanjaya
authors.forename: Yi-Feng
authors.initials: YF
authors.lastname: Wang
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Chiba
mesh_terms: D000578:Amidines / Q000737:chemistry*; D000586:Amination; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003959:Diamines; D007093:Imidazoles / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000578:Amidines; D000588:Amines; D003959:Diamines; D007093:Imidazoles; D003300:Copper