title: ChEMBLSpace--a graphical explorer of the chemogenomic space covered by the ChEMBL database.
abstract: The ChEMBLSpace graphical explorer enables the identification of compounds from the ChEMBL database, which exhibit a desirable polypharmacology profile. This profile can be predefined or created iteratively, and the tool can be extended to other data sources.
authors.affiliation: Department of Medicinal Chemistry, Lilly Research Laboratories, Eli Lilly and Company, Erl Wood Manor, Surrey GU20 6PH, UK.
authors.forename: Nikolas
authors.initials: N
authors.lastname: Fechner
authors.forename: George
authors.initials: G
authors.lastname: Papadatos
authors.forename: David
authors.initials: D
authors.lastname: Evans
authors.forename: John Richard
authors.initials: JR
authors.lastname: Morphy
authors.forename: Suzanne Clare
authors.initials: SC
authors.lastname: Brewerton
authors.forename: David
authors.initials: D
authors.lastname: Thorner
authors.forename: Michael
authors.initials: M
authors.lastname: Bodkin
mesh_terms: D003196:Computer Graphics; D062126:Databases, Chemical; D006801:Humans; D008024:Ligands; D019338:Polypharmacy; D011506:Proteins / Q000187:drug effects; D012984:Software
chemical_list: D008024:Ligands; D011506:Proteins