title: Are there race-dependent endothelial cell responses to exercise?
abstract: African Americans have an endothelial dysfunction that likely contributes to their high prevalence of hypertension. Endothelial cell (EC) responses to stimuli could play a role in the development of endothelial dysfunction and hypertension. High physiological levels of vascular laminar shear stress can alter EC phenotype profoundly. It is not known whether there are race-dependent EC responses to laminar shear stress.
authors.affiliation: Vascular Health Laboratory, Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA. brownmd@temple.edu
authors.forename: Michael D
authors.initials: MD
authors.lastname: Brown
authors.forename: Deborah L
authors.initials: DL
authors.lastname: Feairheller
mesh_terms: D001741:Black or African American; D015415:Biomarkers / Q000378:metabolism; D042783:Endothelial Cells / Q000378:metabolism / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D054624:Health Status Disparities; D006801:Humans; D007249:Inflammation / Q000208:ethnology / Q000378:metabolism / Q000503:physiopathology; D009569:Nitric Oxide / Q000378:metabolism; D019001:Nitric Oxide Synthase / Q000378:metabolism; D018384:Oxidative Stress / Q000502:physiology; D013312:Stress, Physiological / Q000502:physiology; D014652:Vascular Diseases / Q000208:ethnology* / Q000378:metabolism / Q000503:physiopathology; D044465:White People
chemical_list: D015415:Biomarkers; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase