title: Water-soluble bis-triazolyl benzochalcogendiazole cycloadducts as tunable metal ion sensors.
abstract: A series of bis-triazolyl benzochalcogendiazoles was synthesized to investigate their metal-binding capabilities. These fluorophores were formed through the cycloaddition of an ethynylated benzochalcogendiazole and a water-soluble azide. Variation of the chalcogen heteroatom was seen to affect the photophysical properties as well as the metal-binding activity. These cycloadducts exhibited a distinct response to Cu(2+), Ni(2+), and Ag(+) in water. The binding affinity for the copper and nickel ions increased moving the chalcogen atom from O to Se. Statistical analysis of the spectral data enabled differentiation of Ag(+), Cu(2+), and Ni(2+) ions.
authors.affiliation: Organisch Chemisches Institut, Universität Heidelberg, Im Neuenheimer Feld 270, Heidelberg 69120, Germany.
authors.forename: Jonathan J
authors.initials: JJ
authors.lastname: Bryant
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Lindner
authors.forename: Uwe H F
authors.initials: UH
authors.lastname: Bunz