title: Challenges in transcatheter aortic valve implantation.
abstract: Although safety and efficacy of TAVI was improved with next-generation equipment, experience, and careful patient selection, some worrisome complications associated with the procedure remain. Current hot topics in transcatheter aortic valve implantation include patient selection, valve sizing, paravalvular regurgitation, cerebrovascular accidents, vascular complications and need for a permanent pacemaker. In this article we review the pathophysiology, avoidance and treatment options for these complications.
authors.affiliation: St. Paul's Hospital, University of British Columbia, Vancouver, Canada. stefan.Toggweiler@luks.ch
authors.forename: Stefan
authors.initials: S
authors.lastname: Toggweiler
authors.forename: John G
authors.initials: JG
authors.lastname: Webb
mesh_terms: D001022:Aortic Valve Insufficiency / Q000503:physiopathology / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000503:physiopathology / Q000601:surgery*; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D006350:Heart Valve Prosthesis / Q000009:adverse effects / Q000592:standards; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D010138:Pacemaker, Artificial / Q000592:standards / Q000706:statistics & numerical data; D018579:Patient Selection; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control*; D018570:Risk Assessment; D020521:Stroke / Q000209:etiology / Q000517:prevention & control; D057772:Vascular System Injuries / Q000209:etiology / Q000517:prevention & control*