title: The association between spatial distribution of common malignancies and soil lead concentration in Isfahan, Iran.
abstract: BACKGROUND
  Malignancies are primarily environmental diseases mostly attributed to environmental factors. By plotting the prevalence and spatial distribution maps, important differences can be observed in detail. This study aimed to determine the association between map distribution of malignancies and the geological phenomena of lead (Pb) accumulation in soil in the province of Isfahan, Iran.
  
  
  METHODS
  Spatial distribution maps of malignant diseases were plotted by using data recorded during 2007 to 2009 in the Isfahan Cancer Registry Program. Data on Pb accumulation in soil was obtained from the National Geological Survey and Mineral Exploration. Pb concentrations were documented in three parts of agricultural, non-agricultural, urban, and industrial land. The geographical mapping of cancers and soil Pb were then incorporated into a geographic information system (GIS) to create a spatial distribution model.
  
  
  RESULTS
  The spatial distributions of ten common malignant diseases in the province, i.e. skin cancers, hematological malignancies, and breast cancers, followed by other malignancies were scattered based on Pb distribution. In fact, common cancers were more prevalent in the parts of the province where soil Pb was more abundant.
  
  
  CONCLUSIONS
  The findings of this study underscore the importance of preventing Pb exposure and controlling industrial production of Pb. The data is also important to establish further effects modeling for cancers. Moreover, physicians and health professionals should consider the impact of environmental factors on their patients' health.
authors.affiliation: PhD Student, Department of Geomorphology, Isfahan University, Isfahan, Iran.
authors.forename: Masoumeh
authors.initials: M
authors.lastname: Rashidi
authors.forename: Mohammad Hossein
authors.initials: MH
authors.lastname: Rameshat
authors.forename: Hadi
authors.initials: H
authors.lastname: Gharib
authors.forename: Reza
authors.initials: R
authors.lastname: Rouzbahani
authors.forename: Majid
authors.initials: M
authors.lastname: Ghias
authors.forename: Parinaz
authors.initials: P
authors.lastname: Poursafa