title: [A case that showed an improved quality of life for rectal gastrointestinal stromal tumor patient treated with cytoreductive surgery].
abstract: A 49-year-old man was admitted to another hospital with the complaint of difficulty in defecating. He underwent laparotomy, and investigation of the biopsy revealed a huge intraperitoneal tumor. He began to take imatinib in April 2008 following a diagnosis of gastrointestinal stromal tumor (GIST), but the tumor increased in size. He was referred to our hospital for oral administration of sunitinib to reduce the tumor size. The tumor was 30 cm in diameter, and there were several peritoneal metastases around the liver. He began to take sunitinib in February 2009. The tumor increased in size from August 2010 but a partial remission was noted. We performed cytoreductive surgery in April 2011 as palliative care, but the tumor size increased again in October. We performed cytoreductive surgery again, but he died in December 2011. Although cytoreductive surgery for GIST is a potential treatment option, we suggest supportive care.
authors.affiliation: Dept. of Surgery, Tokyo Medical University, Japan.
authors.forename: Soh
authors.initials: S
authors.lastname: Katayanagi
authors.forename: Osamu
authors.initials: O
authors.lastname: Konno
authors.forename: Daiki
authors.initials: D
authors.lastname: Ono
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Yokoyama
authors.forename: Takeshi
authors.initials: T
authors.lastname: Suda
authors.forename: Sumito
authors.initials: S
authors.lastname: Hoshino
authors.forename: Kazushige
authors.initials: K
authors.lastname: Ito
authors.forename: Yu
authors.initials: Y
authors.lastname: Takagi
authors.forename: Akihiko
authors.initials: A
authors.lastname: Tsuchida
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Aoki
authors.forename: Hiromi
authors.initials: H
authors.lastname: Serizawa
authors.forename: Motohide
authors.initials: M
authors.lastname: Shimazu
mesh_terms: D017809:Fatal Outcome; D046152:Gastrointestinal Stromal Tumors / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D011788:Quality of Life; D012004:Rectal Neoplasms / Q000601:surgery*