title: Trogocytosis generates acquired regulatory T cells adding further complexity to the dysfunctional immune response in multiple myeloma.
abstract: Trogocytosis, which results in the acquisition of myeloma cell-derived membrane proteins by T cells, and hence generates novel regulatory T cells, adds to the growing list of immune defects of multiple myeloma patients. The increasing complexity of the cancer-associated immune defects must be attentively considered for attempting to improve the so-far unsatisfactory rates of clinical responses to immunotherapy in patients affected by multiple myeloma and other malignancies.
authors.affiliation: Institute of Haematology; Royal Prince Alfred Hospital; Sydney, Australia.
authors.forename: Ross
authors.initials: R
authors.lastname: Brown
authors.forename: Hayley
authors.initials: H
authors.lastname: Suen
authors.forename: James
authors.initials: J
authors.lastname: Favaloro
authors.forename: Shihong
authors.initials: S
authors.lastname: Yang
authors.forename: P Joy
authors.initials: PJ
authors.lastname: Ho
authors.forename: John
authors.initials: J
authors.lastname: Gibson
authors.forename: Douglas
authors.initials: D
authors.lastname: Joshua