title: [Study on chemical constituents from the root bark of Tripterygium hypoglaucum].
abstract: OBJECTIVE
  To study the chemical constituents of the root bark of Tripterygium hypoglaucum.
  
  
  METHODS
  Column chromatography was used to separate the chemical constituents. The structures were determined by application of spectroscopic (NMR, MS) and chemical methods.
  
  
  RESULTS
  Eleven compounds were isolated and identified as 4'-0-(-) methylepigallocatechin (1),3,4-dimethoxyphenyl-beta-D-glucopyranoside (2), 3,4,5-trimethoxyphenyl-f-D-glucopyranoside (3), (2R,3R)-3,5,7,3',5'-pentahydroxyflavan (4), 2-O-deacetyleuonine (5), tripfordine C (6), peritassine A (7) hypoglaunine C (8), wilfortrine (9), wilforgine (10) and wilfordine (11).
  
  
  CONCLUSIONS
  Compounds 1-6 are isolated from this plant for the first time.
authors.affiliation: State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China. xiefugui01@163.com
authors.forename: Fu-Gui
authors.initials: FG
authors.lastname: Xie
authors.forename: Chuang-Jun
authors.initials: CJ
authors.lastname: Li
authors.forename: Jing-Zhi
authors.initials: JZ
authors.lastname: Yang
authors.forename: Yong-Ming
authors.initials: YM
authors.lastname: Luo
authors.forename: Dong-Ming
authors.initials: DM
authors.lastname: Zhang
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D024301:Plant Bark / Q000737:chemistry; D018517:Plant Roots / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D029757:Tripterygium / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D005960:Glucosides; D012717:Sesquiterpenes; C514314:tripfordine C