title: Molecular characterization of high-level mupirocin resistance in Staphylococcus pseudintermedius.
abstract: The genetic analysis of high-level mupirocin resistance (Hi-Mup(r)) in a Staphylococcus pseudintermedius isolate from a dog is presented. The Hi-Mup(r) ileS2 gene flanked by a novel rearrangement of directly repeated insertion sequence IS257 elements was located, together with the aminoglycoside resistance aacA-aphD determinant, on a conjugative plasmid related to the pSK41/pGO1 family plasmids.
authors.affiliation: Department of Microbiology and Infectious Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia. kresimir.matanovic@gmail.com
authors.forename: Krešimir
authors.initials: K
authors.lastname: Matanovic
authors.forename: Eduardo
authors.initials: E
authors.lastname: Pérez-Roth
authors.forename: Selma
authors.initials: S
authors.lastname: Pintarić
authors.forename: Branka
authors.initials: B
authors.lastname: Šeol Martinec
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004251:DNA Transposable Elements; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004285:Dogs; D024881:Drug Resistance, Bacterial; D005260:Female; D023061:Gene Order; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D016712:Mupirocin / Q000494:pharmacology*; D010957:Plasmids; D017422:Sequence Analysis, DNA; D013210:Staphylococcus / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D004251:DNA Transposable Elements; D004269:DNA, Bacterial; D016712:Mupirocin