title: A reversible fluorescence probe based on Se-BODIPY for the redox cycle between HClO oxidative stress and H2S repair in living cells.
abstract: We have developed a new reversible fluorescence probe MPhSe-BOD for the redox cycle process between hypochlorous acid and hydrogen sulfide in solution and in living cells. Confocal microscopy imaging using RAW264.7 cell lines shows that the probe has good cell membrane permeability, and can monitor intracellular HClO/H(2)S redox cycles continuously.
authors.affiliation: State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), 457 Zhongshan Road, Dalian 116023, P. R. China.
authors.forename: Bingshuai
authors.initials: B
authors.lastname: Wang
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.forename: Fabiao
authors.initials: F
authors.lastname: Yu
authors.forename: Ping
authors.initials: P
authors.lastname: Song
authors.forename: Xiaofei
authors.initials: X
authors.lastname: Sun
authors.forename: Songqiu
authors.initials: S
authors.lastname: Yang
authors.forename: Zhangrong
authors.initials: Z
authors.lastname: Lou
authors.forename: Keli
authors.initials: K
authors.lastname: Han
mesh_terms: D000818:Animals; D002460:Cell Line; D002463:Cell Membrane Permeability / Q000187:drug effects; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D006862:Hydrogen Sulfide / Q000737:chemistry / Q000378:metabolism*; D006997:Hypochlorous Acid / Q000737:chemistry / Q000378:metabolism*; D051379:Mice; D015394:Molecular Structure; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D011162:Porphobilinogen / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D012643:Selenium / Q000737:chemistry* / Q000494:pharmacology
chemical_list: C538930:3-anilino difluoroboron dipyrromethene; D005456:Fluorescent Dyes; D006997:Hypochlorous Acid; D011162:Porphobilinogen; D012643:Selenium; D006862:Hydrogen Sulfide