title: Exploring genetic, genomic, and phenotypic data at the rat genome database.
abstract: The laboratory rat, Rattus norvegicus, is an important model of human health and disease, and experimental findings in the rat have relevance to human physiology and disease. The Rat Genome Database (RGD, http://rgd.mcw.edu) is a model organism database that provides access to a wide variety of curated rat data including disease associations, phenotypes, pathways, molecular functions, biological processes, and cellular components for genes, quantitative trait loci, and strains. We present an overview of the database followed by specific examples that can be used to gain experience in employing RGD to explore the wealth of functional data available for the rat.
authors.affiliation: Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: Stanley J F
authors.initials: SJF
authors.lastname: Laulederkind
authors.affiliation: Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: G Thomas
authors.initials: GT
authors.lastname: Hayman
authors.affiliation: Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: Shur-Jen
authors.initials: SJ
authors.lastname: Wang
authors.affiliation: Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: Timothy F
authors.initials: TF
authors.lastname: Lowry
authors.affiliation: Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: Rajni
authors.initials: R
authors.lastname: Nigam
authors.affiliation: Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: Victoria
authors.initials: V
authors.lastname: Petri
authors.affiliation: Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: Jennifer R
authors.initials: JR
authors.lastname: Smith
authors.affiliation: Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: Melinda R
authors.initials: MR
authors.lastname: Dwinell
authors.affiliation: Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: Howard J
authors.initials: HJ
authors.lastname: Jacob
authors.affiliation: Human and Molecular Genetics Center, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: Mary
authors.initials: M
authors.lastname: Shimoyama
mesh_terms: D000818:Animals; D030541:Databases, Genetic; D016678:Genome; D023281:Genomics / Q000379:methods*; D010641:Phenotype; D040641:Quantitative Trait Loci; D051381:Rats / Q000235:genetics*