title: C(22)-steroidal lactone glycosides from stems and leaves of Paris polyphylla var. yunnanensis.
abstract: Further phytochemical investigation on the stems and leaves of Paris polyphylla var. yunnanensis has led to the isolation of three C(22)-steroidal lactone glycosides. Two of these are new compounds, designated as chonglouoside SL-7 (1) and chonglouoside SL-8 (2). Their structures were elucidated on the basis of extensive spectroscopic analysis, as well as comparison with the reported spectroscopic data. This is the first report of C(22)-steroidal lactone glycosides isolated from the Paris genus. Compounds 1 and 3 showed moderate antimicrobic activity against Propionibacterium acnes with MIC values of 31.3 and 3.9μg/mL, respectively.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, PR China.
authors.forename: Xu-Jie
authors.initials: XJ
authors.lastname: Qin
authors.forename: Chang-Xiang
authors.initials: CX
authors.lastname: Chen
authors.forename: Wei
authors.initials: W
authors.lastname: Ni
authors.forename: Huan
authors.initials: H
authors.lastname: Yan
authors.forename: Hai-Yang
authors.initials: HY
authors.lastname: Liu
mesh_terms: D006027:Glycosides / Q000737:chemistry*; D019684:Magnoliopsida / Q000737:chemistry*; D015394:Molecular Structure; D010840:Phytosterols / Q000737:chemistry*; D035261:Plant Components, Aerial; D018515:Plant Leaves / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry*
chemical_list: D006027:Glycosides; D010840:Phytosterols; C582276:chonglouoside SL-7; C582275:chonglouoside SL-8