title: Three new phenolic compounds from the leaves of Rosa sericea.
abstract: Two new flavonoids, quercetin-3-O-β-d-xylopyranosyl-(1→2)-α-d-ribopyranoside (1) and kaempferol-3-O-β-d-xylopyranosyl-(1→2)-α-d-ribopyranoside (2), and one new phenolic derivative, gallicin-p-O-(6'-O-caffeoyl)-β-d-glucoside (3), together with twelve known compounds were isolated from the leaves of Rosa sericea (Rosaceae family). The structures of the new compounds were established by means of spectroscopic analysis including one- and two-dimensional NMR spectroscopy. Some of the isolated compounds were tested for the cytotoxicity of a breast cancer cell (MCF-7) line. The results showed that rubanthrone A (4) has moderate cytotoxicity against the MCF-7 cell line.
authors.affiliation: Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, People's Republic of China.
authors.forename: Jin-Rong
authors.initials: JR
authors.lastname: Li
authors.forename: Jie
authors.initials: J
authors.lastname: Liu
authors.forename: Da-Hai
authors.initials: DH
authors.lastname: He
authors.forename: Hong-Xi
authors.initials: HX
authors.lastname: Xu
authors.forename: Li-Sheng
authors.initials: LS
authors.lastname: Ding
authors.forename: Wei-Kai
authors.initials: WK
authors.lastname: Bao
authors.forename: Zhi-Qiong
authors.initials: ZQ
authors.lastname: Zhou
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhou
mesh_terms: D002109:Caffeic Acids / Q000737:chemistry*; D047309:Flavones / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry*; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D027826:Rosa / Q000737:chemistry*
chemical_list: D002109:Caffeic Acids; D047309:Flavones; D005419:Flavonoids; D005960:Glucosides; D010636:Phenols; C582280:gallicin-p-O-(6'-O-caffeoyl)-beta-D-glucoside; C582279:kaempferol-3-O-beta-D-xylopyranosyl-(1'2)-alpha-D-ribopyranoside; C582278:quercetin-3-O-beta-D-xylopyranosyl-(1'2)-alpha-D-ribopyranoside