title: [Management of non small cell lung cancer].
abstract: BACKGROUND
  The broncopulmonary cancer is a major problem of public health whose diagnosis is most of the time unfavorable. For a long time, strategies of management of cancer have not taken into consideration much the histological type and few authors have studied the implication of histological type of cancer on the future of patients having cancer.
  
  
  OBJECTIVE
  Taking into account the results of recent studies, we propose to review the recent epidemiological and biological aspects of bronchial cancers and then to study the impact on the therapeutic strategy.
  
  
  METHODS
  Review of literature
  
  
  RESULTS
  The scientific progress and the discovery of new mechanisms of carcinogenesis considerably enlarge the therapeutic potential targets and enable to adopt a more specific approach of the cancer cell.
  
  
  CONCLUSIONS
  Despite the progress observed in thoracic cancerology, the benefits concerning survival remain modest. The oncoming of new molecules specifically targeting a stage of oncogenesis enables a better therapeutic selectivity and a lesser toxicity.
authors.affiliation: Service de Pneumologie Allergologie Centre Hospitalo-Universitaire Charles Nicolle, BabSaadoun, Tunis, Tunisia.
authors.forename: Besma
authors.initials: B
authors.lastname: Ourari-Dhahri
authors.forename: Hédi
authors.initials: H
authors.lastname: Ben Slima
authors.forename: Jihen
authors.initials: J
authors.lastname: Ben Amar
authors.forename: Leila
authors.initials: L
authors.lastname: El Gharbi
authors.forename: Mohamed
authors.initials: M
authors.lastname: Ali
authors.forename: Saloua
authors.initials: S
authors.lastname: Baccar Azzabi
authors.forename: Hichem
authors.initials: H
authors.lastname: Aouina
authors.forename: Hend
authors.initials: H
authors.lastname: Bouacha
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000453:epidemiology / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology / Q000235:genetics / Q000473:pathology / Q000628:therapy*