title: Beyond the hundred dollar genome--drug discovery futures.
abstract: The advent of silicon chip based technologies for genome sequencing promises continuing exponential falls in the reagent costs of sequencing. When every patient has a full genome sequence as part of their medical records the science of drug discovery and drug design must adapt and improve to meet this challenge. This series covers computational, and experimental approaches for small molecules and biologics. From the virtual patient - a computational model of a complete human being, through in silico screening to RNA editing and antibody directed therapies.
authors.affiliation: The Wolfson Institute for Biomedical Research, University College London, Gower Street, London, UK. eiccbdd@wiley.com
authors.forename: David L
authors.initials: DL
authors.lastname: Selwood
mesh_terms: D000906:Antibodies / Q000276:immunology / Q000627:therapeutic use; D019295:Computational Biology; D055808:Drug Discovery; D015894:Genome, Human; D006801:Humans; D017393:RNA Editing; D017422:Sequence Analysis, DNA
chemical_list: D000906:Antibodies