title: Clinical experience of 3T intraoperative magnetic resonance imaging integrated neurosurgical suite in Shanghai Huashan Hospital.
abstract: BACKGROUND
  Intraoperative magnetic resonance imaging (iMRI) dates back to the 1990s and has been successfully applied in neurosurgery but they were low-field iMRI (< 1.0T). This paper reports the clinical experience with a 3T iMRI-integrated neurosurgical suite in Huashan Hospital, Shanghai, China.
  
  
  METHODS
  From September 2010 through March 2012, 373 consecutive patients underwent neurological surgery under guidance with 3T iMRI. A retrospective analysis was conducted regarding clinical efficiency.
  
  
  RESULTS
  All surgery in the 373 patients was safe. The ratio of gross total resection for cerebral gliomas (n = 161) was increased from 55.90% to 87.58%. The ratio of benefit in extent of resection was 39.13%. One hundred and fifty eight of the 161 glioma patients accomplished follow-up at 3 months postoperatively. Twenty of 161 patients (12.42%) suffered from early motor deficit after surgery. Late motor deficit was however observed in five of 158 patients (3.16%). Twenty-one of 161 patients (13.04%) had early speech deficit and late speech deficit was only observed in six of 158 patients (3.80%). The ratio of gross total resection for pituitary adenomas (n = 49) was increased from 77.55% to 85.71%. The ratio of benefit in extent of resection was 10.2%. There were no iMRI-related adverse events even for patients who underwent awake craniotomy.
  
  
  CONCLUSIONS
  The 3T iMRI integrated neurosurgical suite provides high-quality intraoperative structural and functional imaging for real-time tumor resection control and accurate functional preservation, resulting in an improvement in maximal safe brain surgery.
authors.affiliation: Department of Neurosurgery, Fudan University, Shanghai, China.
authors.forename: Tian-ming
authors.initials: TM
authors.lastname: Qiu
authors.forename: Cheng-jun
authors.initials: CJ
authors.lastname: Yao
authors.forename: Jin-song
authors.initials: JS
authors.lastname: Wu
authors.forename: Zhi-guang
authors.initials: ZG
authors.lastname: Pan
authors.forename: Dong-xiao
authors.initials: DX
authors.lastname: Zhuang
authors.forename: Gen
authors.initials: G
authors.lastname: Xu
authors.forename: Feng-ping
authors.initials: FP
authors.lastname: Zhu
authors.forename: Jun-feng
authors.initials: JF
authors.lastname: Lu
authors.forename: Xiu
authors.initials: X
authors.lastname: Gong
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.forename: Zhong
authors.initials: Z
authors.lastname: Yang
authors.forename: Jian-bin
authors.initials: JB
authors.lastname: Shi
authors.forename: Feng-ping
authors.initials: FP
authors.lastname: Huang
authors.forename: Ying
authors.initials: Y
authors.lastname: Mao
authors.forename: Liang-fu
authors.initials: LF
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D002681:China; D005260:Female; D005910:Glioma / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods*; D055815:Young Adult