title: [Long-surviving patient with hilar cholangiocarcinoma by gemcitabine monotherapy].
abstract: An 80-year-old woman visited our department with the complaint of icterus and brown urine. After detailed examination, she was diagnosed with cT4N0M (-), cStage IVa, hilar cholangiocarcinoma. We believed that she could be cured with surgery, but she and her family did not agree to the surgical procedure. Chemotherapy was scheduled, and gemcitabine (GEM) therapy was started in April 2011. GEM therapy reduced significantly the level of the CA 19-9 tumor marker, and diagnostic imaging allowed a judgment of partial response or stable disease after 18 months. In the present report, we describe a case of a patient with hilar cholangiocarcinoma who achieved long-term survival with GEM therapy. We also include a brief literature review.
authors.affiliation: Dept. of Surgery, Hasuda Hospital, Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Iwata
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Yoshida
authors.forename: Eriko
authors.initials: E
authors.lastname: Katsuta
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Aoyagi
authors.forename: Taro
authors.initials: T
authors.lastname: Takahata
authors.forename: Kumi
authors.initials: K
authors.lastname: Hasegawa
authors.forename: Jun
authors.initials: J
authors.lastname: Kaneko
authors.forename: Shizuaki
authors.initials: S
authors.lastname: Maejima
mesh_terms: D000369:Aged, 80 and over; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D001650:Bile Duct Neoplasms / Q000188:drug therapy* / Q000473:pathology; D001653:Bile Ducts, Intrahepatic / Q000473:pathology*; D018281:Cholangiocarcinoma / Q000188:drug therapy* / Q000473:pathology; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D013997:Time Factors; D000093542:Gemcitabine
chemical_list: D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000093542:Gemcitabine