title: [Comparative characteristic of the local application of anti-inflammatory agents for the treatment of otitis externa and otitis media].
abstract: The objective of the present work was the clinical study of candibiotic exhibitic antibacterial, antimycotic, anti-inflammatory, and anesthetic properties when applied for the treatment of otitis externa and otitis media. This agent was included together with traditionally used systemic medications in the combined treatment of 26 patients. It was applied in the form of endoaural drops, transtubal administration through a catheter, and transtympanic pumping by the Politzer balloon technique (in case of perforation). In the patients with otomycosys, the preparation was used for the treatment of the external acoustic canal after the removal of fungal masses thrice daily for 1 month. Good clinical effect achieved in all the patients was manifest as the normal otoscopic picture and less frequent complaints on days 8-10 after the onset of therapy. Its maximum duration was 21 days. Positive dynamics (pain relief) was apparent within the first 2 days of the treatment. Fungal mycelium was absent after 14-16 days of the treatment in 100% of the patients initially presenting with yeast-like fungi.
authors.forename: M M
authors.initials: MM
authors.lastname: Magomedov
authors.forename: A E
authors.initials: AE
authors.lastname: Starostina
authors.forename: M G
authors.initials: MG
authors.lastname: Magomedov
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000777:Anesthetics / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000893:Anti-Inflammatory Agents / Q000145:classification / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use*; D057186:Comparative Effectiveness Research; D004338:Drug Combinations; D004357:Drug Synergism; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D010032:Otitis Externa / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D010033:Otitis Media / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D010146:Pain / Q000188:drug therapy / Q000209:etiology; D059408:Pain Management; D019999:Pharmaceutical Solutions; D016896:Treatment Outcome
chemical_list: D000777:Anesthetics; D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D004338:Drug Combinations; D005938:Glucocorticoids; D019999:Pharmaceutical Solutions