title: Two cases of hemolytic uremic syndrome caused by Streptococcus pneumoniae serotype 3, one being a vaccine failure.
abstract: We report two cases of Streptococcus pneumoniae-associated hemolytic uremic syndrome (SP-HUS) caused by serotype 3. One case occurred in an unvaccinated boy and 1 in a girl vaccinated with the 13-valent pneumococcal conjugate vaccine. SP-HUS must be considered in children, and conjugate vaccines may be less effective against serotype 3 than other serotypes.
authors.affiliation: Department of Pediatrics, Queen Silvia Children's Hospital Gothenburg, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. daniel.novak@vgregion.se
authors.forename: Daniel
authors.initials: D
authors.lastname: Novak
authors.forename: Anna
authors.initials: A
authors.lastname: Lundgren
authors.forename: Susanne
authors.initials: S
authors.lastname: Westphal
authors.forename: Sindri
authors.initials: S
authors.lastname: Valdimarsson
authors.forename: Martin L
authors.initials: ML
authors.lastname: Olsson
authors.forename: Birger
authors.initials: B
authors.lastname: Trollfors
mesh_terms: D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000382:microbiology*; D006801:Humans; D007223:Infant; D008297:Male; D011008:Pneumococcal Infections / Q000382:microbiology*; D022242:Pneumococcal Vaccines / Q000494:pharmacology; D013296:Streptococcus pneumoniae / Q000302:isolation & purification*; D017211:Treatment Failure
chemical_list: C538862:13-valent pneumococcal vaccine; D022242:Pneumococcal Vaccines