title: A tertiary amine catalyzed carbocyclization sequence to furnish spirocyclo hexene systems having vicinal quaternary stereocenters.
abstract: Two types of enolates can be formed stepwise from enolisable 1,3-dicarbonyl-substituted propene systems in the presence of catalytic amounts of 1,4-diazabicyclo[2.2.2]octane (DABCO) to accomplish a highly selective carbocyclization with β,γ-unsaturated α-keto esters, giving functionalized spiroketones with vicinal quaternary stereocenters.
authors.affiliation: Department of Chemistry, Zhejiang University, Hangzhou, China.
authors.forename: Jindian
authors.initials: J
authors.lastname: Duan
authors.forename: Fangyi
authors.initials: F
authors.lastname: Cao
authors.forename: Xiaoqin
authors.initials: X
authors.lastname: Wang
authors.forename: Cheng
authors.initials: C
authors.lastname: Ma