title: Analgesia with remifentanil versus anesthesia with propofol-alfentanil for transvaginal oocyte retrieval: a randomized trial on their impact on in vitro fertilization outcome.
abstract: BACKGROUND
  The aim of this study was to compare the effects of analgesia with remifentanil versus anesthesia with propofol and alfentanil on in vitro fertilization outcome.
  
  
  METHODS
  The study included 58 women undergoing ultrasound transvaginal oocyte retrieval, who were randomized to receive either analgesia with remifentanil (n = 29) or anesthesia with propofol and alfentanil (n = 29). The subjects were compared for number of collected and matured oocytes, fertilization rate, cleavage rate, implantation rate, pregnancy rate, and embryo quality. Anesthesia related side effects and both patient and gynecologist satisfaction were recorded.
  
  
  RESULTS
  There were no significant differences in collected oocytes, matured oocytes, fertilization and cleavage rate, embryo quality and implantation and pregnancy rate between the two groups. There was no difference regarding side effects and both patient and gynecologist satisfaction.
  
  
  CONCLUSIONS
  Analgesia with remifentanil compared with anesthesia with propofol and alfentanil, provided equally effective and safe anesthesia during ultrasound transvaginal oocyte retrieval.
authors.affiliation: 2nd Department of Anesthesiology, School of Medicine, University of Athens, "Attikon" Hospital, Athens, Greece. matsota@yahoo.gr
authors.forename: Paraskevi
authors.initials: P
authors.lastname: Matsota
authors.forename: Tatiana
authors.initials: T
authors.lastname: Sidiropoulou
authors.forename: Chrysanthi
authors.initials: C
authors.lastname: Batistaki
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Giannaris
authors.forename: Aggeliki
authors.initials: A
authors.lastname: Pandazi
authors.forename: Helen
authors.initials: H
authors.lastname: Krepi
authors.forename: Kalliopi
authors.initials: K
authors.lastname: Christodoulaki
authors.forename: Georgia
authors.initials: G
authors.lastname: Kostopanagiotou
mesh_terms: D000328:Adult; D015760:Alfentanil / Q000008:administration & dosage*; D000698:Analgesia; D000701:Analgesics, Opioid / Q000627:therapeutic use*; D000758:Anesthesia; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D054315:Oocyte Retrieval / Q000379:methods*; D010880:Piperidines / Q000627:therapeutic use*; D011247:Pregnancy; D018873:Pregnancy Rate; D015742:Propofol / Q000008:administration & dosage*; D000077208:Remifentanil; D016896:Treatment Outcome
chemical_list: D000701:Analgesics, Opioid; D018686:Anesthetics, Intravenous; D010880:Piperidines; D015760:Alfentanil; D000077208:Remifentanil; D015742:Propofol