title: Synthesis of multisubstituted pyridines.
abstract: By utilizing amino allenes, aldehydes, and aryl iodides as readily available building blocks, a simple and modular synthesis of multisubstituted pyridines with flexible control over the substitution pattern has been achieved. The method employs a two-step procedure involving the preparation of "skipped" allenyl imines and a subsequent palladium-catalyzed cyclization.
authors.affiliation: Davenport Research Laboratories, Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, Ontario, M5S 3H6, Canada.
authors.forename: Zhi
authors.initials: Z
authors.lastname: He
authors.forename: Dennis
authors.initials: D
authors.lastname: Dobrovolsky
authors.forename: Piera
authors.initials: P
authors.lastname: Trinchera
authors.forename: Andrei K
authors.initials: AK
authors.lastname: Yudin