title: Sonochemical fabrication of Fe3O4 nanoparticles on reduced graphene oxide for biosensors.
abstract: This study synthesized Fe(3)O(4) nanoparticles of 30-40nm by a sonochemical method, and these particles were uniformly dispersed on the reduced graphene oxide sheets (Fe(3)O(4)/RGO). The superparamagnetic property of Fe(3)O(4)/RGO was evidenced from a saturated magnetization of 30emu/g tested by a sample-vibrating magnetometer. Based on the testing results, we proposed a mechanism of ultrasonic waves to explain the formation and dispersion of Fe(3)O(4) nanoparticles on RGO. A biosensor was fabricated by modifying a glassy carbon electrode with the combination of Fe(3)O(4)/RGO and hemoglobin. The biosensor showed an excellent electrocatalytic reduction toward H(2)O(2) at a wide, linear range from 4×10(-6) to 1×10(-3)M (R(2)=0.994) as examined by amperometry, and with a detection limit of 2×10(-6)M. The high performance of H(2)O(2) detection is attributed to the synergistic effect of the combination of Fe(3)O(4) nanoparticles and RGO, promoting the electron transfer between the peroxide and electrode surface.
authors.affiliation: State Key Lab of Metal Matrix Composites, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, PR China. smzhu@sjtu.edu.cn
authors.forename: Shenmin
authors.initials: S
authors.lastname: Zhu
authors.forename: Jingjing
authors.initials: J
authors.lastname: Guo
authors.forename: Junping
authors.initials: J
authors.lastname: Dong
authors.forename: Zhaowen
authors.initials: Z
authors.lastname: Cui
authors.forename: Tao
authors.initials: T
authors.lastname: Lu
authors.forename: Chenglin
authors.initials: C
authors.lastname: Zhu
authors.forename: Di
authors.initials: D
authors.lastname: Zhang
authors.forename: Jun
authors.initials: J
authors.lastname: Ma
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods; D006108:Graphite / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000032:analysis; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry; D010316:Particle Size; D013010:Sonication / Q000379:methods*; D013499:Surface Properties
chemical_list: D058185:Magnetite Nanoparticles; D010087:Oxides; D006108:Graphite; D006861:Hydrogen Peroxide