title: Sai-rei-to-induced lung injury: a case report and brief review of the literature.
abstract: An 81-year-old man was admitted to our hospital due to persistent fever and dyspnea with pulmonary infiltrates. He was treated successfully by discontinuing his current medications, including Sai-rei-to, and administering glucocorticoids. Drug lymphocyte stimulation tests showed a positive result for Sai-rei-to alone, and the resumption of other regular drugs did not re-induce the lung injury. Therefore, we diagnosed the patient with Sai-rei-to-induced lung injury. Sai-rei-to is a combination drug that consists of Sho-saiko-to and Gorei-san. This paper briefly reviews drug-induced lung injury caused by Sai-rei-to or its components with a case report.
authors.affiliation: Department of Internal Medicine 2, Oita University Faculty of Medicine, Japan.
authors.forename: Kosaku
authors.initials: K
authors.lastname: Komiya
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishii
authors.forename: Minoru
authors.initials: M
authors.lastname: Ohama
authors.forename: Masahiro
authors.initials: M
authors.lastname: Uchida
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Tsubone
authors.forename: Tomohiko
authors.initials: T
authors.lastname: Iwashita
authors.forename: Hajime
authors.initials: H
authors.lastname: Miyajima
authors.forename: Eiji
authors.initials: E
authors.lastname: Okabe
authors.forename: Taisuke
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Bunroku
authors.initials: B
authors.lastname: Matsumoto
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Kadota
mesh_terms: D000369:Aged, 80 and over; D004365:Drugs, Chinese Herbal / Q000009:adverse effects*; D006801:Humans; D055370:Lung Injury / Q000139:chemically induced*; D008297:Male
chemical_list: D004365:Drugs, Chinese Herbal; C080903:sairei-to