title: Analysis of Pogostemon cablin from pharmaceutical research to market performances.
abstract: BACKGROUND
  Pogostemon cablin (P. cablin), called Ciruicao or Guanghuoxiang, is a well-known Chinese materia medica in southeast Asia that is widely used in gastrointestinal disease and exterior syndromes, being confirmed by both in vitro and in vivo studies. To exploit this traditional medicine that adequately fits modern drugs, however, a comprehensive review about its pharmacy research and market performance is extremely necessary.
  
  
  METHODS
  This article reviews various components extracted from this plant as well as the biological activities derived from those chemical compositions. The authors summarize the quality evaluation and highlight the therapeutic effects of P. cablin, such as antiviral activities, antioxidation effect, antiinflammatory, analgesic activities, and intestinal barrier function protection. The preparation profile of P. cablin and some future related research were also described in this review. Last but not least, a market performance analysis was conducted.
  
  
  CONCLUSIONS
  P. cablin has beneficial therapeutic potential as an effective adaptogenic herbal remedy in clinic. Molecular mechanisms and active targets of P. cablin compounds, the qualitative and quantitative standard of P. cablin, as well as novel drug delivery systems of P. cablin, would be developed.
authors.affiliation: University of Macau, Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, Av. Padre Tomas Pereira S.J., Taipa, Macao, China.
authors.forename: Meiwan
authors.initials: M
authors.lastname: Chen
authors.forename: Jinming
authors.initials: J
authors.lastname: Zhang
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Lai
authors.forename: Shengpeng
authors.initials: S
authors.lastname: Wang
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.forename: Jian
authors.initials: J
authors.lastname: Xiao
authors.forename: Chaomei
authors.initials: C
authors.lastname: Fu
authors.forename: Hao
authors.initials: H
authors.lastname: Hu
authors.forename: Yitao
authors.initials: Y
authors.lastname: Wang
mesh_terms: D002681:China; D055808:Drug Discovery / Q000191:economics / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology / Q000627:therapeutic use; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D019686:Lamiaceae / Q000737:chemistry* / Q000254:growth & development; D040541:Marketing; D008516:Medicine, Chinese Traditional; D015394:Molecular Structure; D009822:Oils, Volatile / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry / Q000254:growth & development
chemical_list: D004365:Drugs, Chinese Herbal; D009822:Oils, Volatile; C483658:Pogostone