title: [Changes of blood viscosity and erythrocyte rheology in acute hypoxic hypoxia mices].
abstract: OBJECTIVE
  To observe the changes of blood viscosity and erythrocyte rheology in mice after acute hypoxic hypoxia (AHH).
  
  
  METHODS
  Thirty-two Kui-ming mice were randomly divided into control group, AHH group (duplicating AHH model, and divided into 5 min, 8 min, 11 min subgroups), the blood sample was taken out from heart after neck dislocation at corresponding times, for detecting the blood viscosity and erythrocyte rheology indices.
  
  
  RESULTS
  Compared with control group, the whole blood viscosity at different shears, whole blood reduced viscosity, whole blood relative viscosity were lower and the erythrocytes aggregation index was higher in AHH 5 min group; the electrophoresis time was longer and the electrophoresis length, migration of erythrocyte were lower in AHH 8 min and AHH 11 min groups. The whole blood reduced viscosity, whole blood relative viscosity, erythrocytes aggregation index in AHH 8 min group were higher, and the erythrocyte deformability index was lower significantly than that of AHH 5 min group, respectively.
  
  
  CONCLUSIONS
  These data suggested that the AHH could induce the blood viscosity and electrophoresis ability.
authors.affiliation: Institute of Microcirculation, Hebei North University, Zhangjiakou 075029, China.
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.forename: Xin-Miao
authors.initials: XM
authors.lastname: Li
authors.forename: Ji
authors.initials: J
authors.lastname: Feng
authors.forename: Guo-Jie
authors.initials: GJ
authors.lastname: Xu
authors.forename: Xiao-Bin
authors.initials: XB
authors.lastname: Liu
authors.forename: Hua
authors.initials: H
authors.lastname: Jiang
authors.forename: Chun-Yu
authors.initials: CY
authors.lastname: Niu
authors.forename: Zi-Gang
authors.initials: ZG
authors.lastname: Zhao
mesh_terms: D000818:Animals; D001809:Blood Viscosity; D004903:Erythrocyte Aggregation; D004907:Erythrocyte Deformability; D004909:Erythrocyte Indices; D004912:Erythrocytes / Q000502:physiology*; D000860:Hypoxia / Q000097:blood* / Q000209:etiology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains