title: Current and potential treatments for cervical cancer.
abstract: Cervical cancer is the third most common carcinoma in women worldwide. Despite increasing efforts to improve therapy in this disease, a significant proportion of women still die, mostly from recurrent or chemoresistant disease. This review discusses current treatments for early cervical cancer, advanced disease, and recurrent cervical cancer, and covers concurrent chemoradiation, neoadjuvant chemotherapy before surgery and radiation, single agent treatment, combination treatment, platinum-based and non-platinum based therapy. We also discuss promising therapeutics trategies for cervical cancer including targeted therapy, cell-based therapy, combined siRNA and chemotherapy, and immunotherapy.
authors.affiliation: Centre for Vascular Research, University of New South Wales, Sydney, NSW 2052, Australia.
authors.forename: Grace P C
authors.initials: GP
authors.lastname: Yee
authors.forename: Paul
authors.initials: P
authors.lastname: de Souza
authors.forename: Levon M
authors.initials: LM
authors.lastname: Khachigian
mesh_terms: D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007167:Immunotherapy; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*