title: Spinal cord injury: harnessing spike timing to induce plastic change.
abstract: A recent study shows that a spike-timing-dependent plasticity protocol can potentiate corticospinal transmission to finger muscle motoneurons, in both volunteers and in patients with incomplete spinal injury. In patients, the protocol improved voluntary muscle output and performance on a peg-board test.
authors.affiliation: Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London, UK. r.lemon@ucl.ac.uk
authors.forename: Roger
authors.initials: R
authors.lastname: Lemon
mesh_terms: D002540:Cerebral Cortex / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D009043:Motor Activity; D013116:Spinal Cord / Q000503:physiopathology*; D013119:Spinal Cord Injuries / Q000503:physiopathology*; D009435:Synaptic Transmission