title: [DNA sequencing using specific long-range interaction between macromolecules].
abstract: On the basis of the theory of specific long-range interaction between long molecules the approach has been elaborated for the "fast reading" of nucleotide sequences in sole DNA molecule. Firstly, a stretching force applies to the molecule that causes its unwinding from B-form to so called S-form. Then, a molecule disposes in a stretched state on the background. After this, the electrostatic potential is estimated in the space along the DNA filament. Information obtained is sufficient for the deduction of the nucleotide sequence in DNA. Another approach to the "reading" of information reduces to the measurement of the filament element deformation induced by electrostatic field from the electrode that stretches the filament by alternating current applied.
authors.forename: V A
authors.initials: VA
authors.lastname: Namiot
authors.forename: A A
authors.initials: AA
authors.lastname: Anashkina
authors.forename: I V
authors.initials: IV
authors.lastname: Filatov
authors.forename: V G
authors.initials: VG
authors.lastname: Tumanian
authors.forename: N G
authors.initials: NG
authors.lastname: Esipova
mesh_terms: D055592:Biophysical Phenomena; D004247:DNA / Q000737:chemistry*; D004560:Electricity; D059014:High-Throughput Nucleotide Sequencing / Q000295:instrumentation* / Q000379:methods*; D008024:Ligands; D046911:Macromolecular Substances; D008962:Models, Theoretical
chemical_list: D008024:Ligands; D046911:Macromolecular Substances; D004247:DNA