title: [Endoscopic retrograde biliary drainage for the liver metastases from colorectal cancer and obstructive jaundice].
abstract: The success of biliary drainage in patients with liver metastases from colorectal cancer and obstructive jaundice influences its prognosis greatly. In this study, we report a retrospective evaluation of endoscopic retrograde biliary drainage in patients with liver metastases from colorectal cancer and obstructive jaundice.
  
  
  METHODS
  From April 2004 to December 2011, 9 patients with liver metastases from colorectal cancer and obstructive jaundice who underwent endoscopic biliary drainage were evaluated retrospectively.
  
  
  RESULTS
  The mean serum levels of total bilirubin, aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase improved significantly after biliary drainage. The median survival time after biliary drainage was 133 days. Only 4 cases were able to resume chemotherapy after biliary drainage, and their prognosis was significantly better than patients who were not able to resume chemotherapy(p=0.014).
  
  
  CONCLUSIONS
  Endoscopic biliary drainage in patients with liver metastases from colorectal cancer and obstructive jaundice was effective, led to the resumption of chemotherapy, and improved prognosis. However, sufficient consideration of the patient's prognosis and performance status is required in order to perform biliary drainage.
authors.affiliation: Dept. of Surgery, Kurume University School of Medicine, Japan.
authors.forename: Yuhei
authors.initials: Y
authors.lastname: Kitasato
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Ishida
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Okabe
authors.forename: Osamu
authors.initials: O
authors.lastname: Tsuruta
authors.forename: Munehiro
authors.initials: M
authors.lastname: Yoshitomi
authors.forename: Gen
authors.initials: G
authors.lastname: Akasu
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Mikagi
authors.forename: Yousuke
authors.initials: Y
authors.lastname: Oka
authors.forename: Yuichirou
authors.initials: Y
authors.lastname: Maruyama
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Kawahara
authors.forename: Hisamune
authors.initials: H
authors.lastname: Sakai
authors.forename: Hiroto
authors.initials: H
authors.lastname: Ishikawa
authors.forename: Toru
authors.initials: T
authors.lastname: Hisaka
authors.forename: Masafumi
authors.initials: M
authors.lastname: Yasunaga
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Horiuchi
authors.forename: Yoshito
authors.initials: Y
authors.lastname: Akagi
authors.forename: Koji
authors.initials: K
authors.lastname: Okuda
authors.forename: Hisafumi
authors.initials: H
authors.lastname: Kinoshita
authors.forename: Kazuo
authors.initials: K
authors.lastname: Shirouzu
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tanaka
mesh_terms: D000328:Adult; D000368:Aged; D003110:Colonic Neoplasms / Q000473:pathology*; D004322:Drainage; D004724:Endoscopy; D005260:Female; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology / Q000628:therapy*; D008113:Liver Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies