title: The clinical characteristics of two anti-OJ (anti-isoleucyl-tRNA synthetase) autoantibody-positive interstitial lung disease patients with polymyositis/dermatomyositis.
abstract: We herein report the clinical and laboratory characteristics of two anti-OJ (anti-isoleucyl-tRNA synthetase) autoantibody-positive interstitial lung disease patients with polymyositis/dermatomyositis (PM/DM). We compared these characteristics with previously published findings. Previous reports and our present cases show that anti-OJ autoantibody-positive interstitial lung disease (ILD) patients with PM/DM lack the manifestations of Raynaud's phenomenon and sclerodactyly and show good prognoses and responses to glucocorticoid therapy. These results indicate that the presence of anti-OJ autoantibodies may be useful for predicting the prognosis of ILD and its clinical course in PM/DM patients.
authors.affiliation: Department of Respiratory Medicine, Kurashiki Central Hospital, Japan. keikunimasa@gmail.com
authors.forename: Kei
authors.initials: K
authors.lastname: Kunimasa
authors.forename: Machiko
authors.initials: M
authors.lastname: Arita
authors.forename: Takashi
authors.initials: T
authors.lastname: Nakazawa
authors.forename: Maki
authors.initials: M
authors.lastname: Tanaka
authors.forename: Kazuya
authors.initials: K
authors.lastname: Tsubouchi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Konishi
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Fukuda
authors.forename: Mika
authors.initials: M
authors.lastname: Saigusa
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Nakagawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ubukata
authors.forename: Yohei
authors.initials: Y
authors.lastname: Korogi
authors.forename: Takao
authors.initials: T
authors.lastname: Fujii
authors.forename: Tsuneyo
authors.initials: T
authors.lastname: Mimori
authors.forename: Tadashi
authors.initials: T
authors.lastname: Ishida
mesh_terms: D000368:Aged; D001323:Autoantibodies / Q000276:immunology*; D003882:Dermatomyositis / Q000150:complications / Q000201:enzymology* / Q000276:immunology*; D005260:Female; D006801:Humans; D007533:Isoleucine-tRNA Ligase / Q000276:immunology*; D017563:Lung Diseases, Interstitial / Q000150:complications / Q000201:enzymology* / Q000276:immunology*; D008297:Male; D017285:Polymyositis
chemical_list: D001323:Autoantibodies; D007533:Isoleucine-tRNA Ligase