title: Review of endogenous endophthalmitis during pregnancy including case series.
abstract: Endogenous endophthalmitis during pregnancy is a rare condition with few reports of such infections in the peri- and post-partum period. We reviewed the literature on endogenous endophthalmitis in pregnancy and also report a series of four patients who presented to our institution from January 2011 to September 2011. We retrospectively reviewed four patients who developed endogenous endophthalmitis either during pregnancy (two patients) or in the post-partum period (two patients--one after abortion and one after normal term delivery). Presenting visual acuity ranged from finger counting at 3 m to no perception of light. Positive cultures included Bacillus mycoides (vitreous) and Klebsiella pneumoniae (urine). Vitrectomy was performed in three patients. In one patient, the vision improved to 20/20. On reviewing the literature and our experience we concluded that endogenous endophthalmitis related to pregnancy is a rare entity with visual prognosis generally being poor. Fluoroquinolones are best avoided. Cephalosporins and amphotericin B are generally the preferred drugs.
authors.affiliation: Srimati Kanuri Santhamma Centre for Vitreo-Retinal Diseases, Hyderabad Eye Research Foundation, Kallam Anji Reddy Campus, L V Prasad Eye Institute, L V Prasad Marg, Banjara Hills, Hyderabad, 500 034, Andhra Pradesh, India.
authors.forename: Chinmaya
authors.initials: C
authors.lastname: Sahu
authors.forename: Kshitiz
authors.initials: K
authors.lastname: Kumar
authors.forename: Manish Kumar
authors.initials: MK
authors.lastname: Sinha
authors.forename: Amarnath
authors.initials: A
authors.lastname: Venkata
authors.forename: Ajit Babu
authors.initials: AB
authors.lastname: Majji
authors.forename: Subhadra
authors.initials: S
authors.lastname: Jalali
mesh_terms: D000028:Abortion, Induced / Q000009:adverse effects; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D009877:Endophthalmitis / Q000209:etiology*; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000382:microbiology; D012189:Retrospective Studies; D014792:Visual Acuity; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents