title: Analysis of uterine and ovarian arterial blood flow and ovarian hormone levels prior to and after hysteroscopic endometrial resection.
abstract: The objective of this study was to evaluate the effect of hysteroscopic endometrial ablation on the ovarian and uterine artery blood flow and on follicle stimulating hormone (FSH) and oestradiol (E2) levels. A total of 26 consecutive women with abnormal uterine bleeding refractory to medical treatment had undergone hysteroscopic electrosurgical transcervical resection of the endometrium (TCRE). Ultrasonographic measurement of ovarian volumes and colour Doppler flow assessment of the uterine and ovarian arteries were performed on all patients before surgery (group 1) and 1 week (group 2) and 6 months (group 3) after surgery. Blood samples were also collected for determination of FSH and E2 levels, 4 weeks before and 1 month after surgery. No statistically significant change was observed between preoperative and postoperative (1st week and 3rd month) volumes of the ovaries. The mean pulsatility index (PI) of the uterine and ovarian artery did not show statistically significant differences between postoperative 1st week and 3rd month measurements of uterine and ovarian artery PI. The increase in serum levels of FSH and E2 after endometrial resection did not reach statistical significance. Although, women may present with climacteric complaints of hot flushes and nocturnal sweating after endometrial resection, this is probably a psychological response to hypomenorrhoea and amenorrhoea, as no statistically significant changes in FSH and E2 levels and uterine/ovarian blood flow were demonstrated in the early postoperative period.
authors.affiliation: Etlik Zubeyde Hanim Women's Health Teaching and Research Hospital, Baskent University School of Medicine, Ankara, Turkey. fsdede@yahoo.com
authors.forename: H
authors.initials: H
authors.lastname: Dede
authors.forename: F S
authors.initials: FS
authors.lastname: Dede
authors.forename: O
authors.initials: O
authors.lastname: Ozdegirmenci
authors.forename: B
authors.initials: B
authors.lastname: Dilbaz
authors.forename: A
authors.initials: A
authors.lastname: Haberal
mesh_terms: D000328:Adult; D055356:Endometrial Ablation Techniques / Q000009:adverse effects*; D004958:Estradiol / Q000097:blood*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D015907:Hysteroscopy / Q000009:adverse effects; D008875:Middle Aged; D010053:Ovary / Q000098:blood supply*; D011184:Postoperative Period; D011446:Prospective Studies; D012039:Regional Blood Flow; D055988:Uterine Artery / Q000502:physiology*
chemical_list: D004958:Estradiol; D005640:Follicle Stimulating Hormone