title: Two different cardiomyopathies in a single patient : hypertrophic cardiomyopathy and left ventricular noncompaction.
abstract: Hypertrophic cardiomyopathy is a complex and relatively common genetic disorder characterized by left ventricular (LV) hypertrophy, usually associated with a nondilated and hyperdynamic chamber with heterogeneous phenotypic expression and clinical course. On the other hand, LV noncompaction is an uncommon cardiomyopathy characterized by the persistence of fetal myocardium with a pattern of prominent trabecular meshwork and deep intertrabecular recesses, systolic dysfunction, and LV dilatation. We report a 29-year-old man with these two different inherent conditions. Our case raises the possibility of a genetic mutation common to these two clinical entities or different gene mutations existing in the same individual.
authors.affiliation: Faculty of Medicine, Department of Cardiology, Marmara University, Yildiz Caddesi Konak Apartmani No: 43/16, 34353, Besiktas/Istanbul, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Sunbul
authors.forename: B
authors.initials: B
authors.lastname: Ozben
authors.forename: B
authors.initials: B
authors.lastname: Mutlu
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D002227:Carbazoles / Q000627:therapeutic use; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics*; D000077261:Carvedilol; D003937:Diagnosis, Differential; D006330:Heart Defects, Congenital / Q000175:diagnosis* / Q000235:genetics* / Q000628:therapy; D006801:Humans; D008297:Male; D011412:Propanolamines / Q000627:therapeutic use; D016896:Treatment Outcome; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000319:Adrenergic beta-Antagonists; D000925:Anticoagulants; D002227:Carbazoles; D011412:Propanolamines; D000077261:Carvedilol; D014859:Warfarin