title: Trimethoprim/sulfamethoxazole induced multiorgan dysfunction.
abstract: A 22-year-old African-American man with AIDS who had recently started on trimethoprim/sulfamethoxazole daily for pneumocystis jirovecii pneumonia prophylaxis presented with an altered mental state, malaise and nausea was found to have hepatitis, pancreatitis, rhabdomyolitis, acute kidney injury and haemolytic anaemia. Cessation of Bactrim and supportive care with volume expansion resolved his clinical symptoms and laboratory abnormalities.
authors.affiliation: Department of Medicine, Madigan Army Hospital, Tacoma, Washington, USA. jjoshlee@gmail.com
authors.forename: Joshua Seung Oh
authors.initials: JS
authors.lastname: Lee
authors.forename: David
authors.initials: D
authors.lastname: Owshalimpur
authors.forename: Christina
authors.initials: C
authors.lastname: Schofield
mesh_terms: D000890:Anti-Infective Agents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009102:Multiple Organ Failure / Q000139:chemically induced*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination