title: Survival after cardiopulmonary arrest with extreme hyperkalaemia and hypothermia in a patient with metformin-associated lactic acidosis.
abstract: Potassium levels are regularly used as a prognostic factor to cease resuscitation in significant hypothermia. In this case report, we highlight how survival is still possible with extreme hyperkalaemia in severe hypothermia. We present a case of a 65-year-old Caucasian man who presented with metformin associated lactic acidosis. On presentation he had potassium of 9.1 mmol/l and a temperature of 31.5 °C. Cardiopulmonary resuscitation was commenced when he went into asystolic arrest. This presentation would commonly make attempts at resuscitation futile with a 100% death rate. However, with appropriate management this patient's condition improved and survival was possible. We provide evidence that survival is possible in profound hyperkalaemia and hypothermia. Effective cardiopulmonary resuscitation with early haemofiltration can be successful.
authors.affiliation: Department of Anaesthesia,  Royal Darwin Hospital, Darwin, Northern Territory,  Australia.
authors.forename: Stan
authors.initials: S
authors.lastname: Tay
authors.forename: I-Lynn
authors.initials: IL
authors.lastname: Lee
mesh_terms: D000140:Acidosis, Lactic / Q000139:chemically induced* / Q000150:complications*; D000368:Aged; D016887:Cardiopulmonary Resuscitation; D006323:Heart Arrest / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D006947:Hyperkalemia / Q000209:etiology*; D007004:Hypoglycemic Agents / Q000009:adverse effects*; D007035:Hypothermia / Q000209:etiology*; D008297:Male; D008687:Metformin / Q000009:adverse effects*; D012720:Severity of Illness Index; D017741:Survivors
chemical_list: D007004:Hypoglycemic Agents; D008687:Metformin