title: Infantile pyknocytosis: an under-recognized form of neonatal hemolytic anemia?
abstract: Infantile pyknocytosis (IP) is an under-recognized hematological entity of newborns that can cause a severe neonatal hemolytic anemia. A careful, prompt, and accurate peripheral blood smear examination is essential to establish the diagnosis. Here we describe the clinical features and histological parameters of 1 case of IP. Spontaneous resolution usually occurs by 4 to 6 months, but red blood cell transfusion may be needed if the anemia is severe.
authors.affiliation: Pediatric Hematology Unit, Centro Hospitalar do Porto, Porto, Portugal. mariapereiracoutinho@hotmail.com
authors.forename: Maria
authors.initials: M
authors.lastname: Coutinho
authors.forename: Emília
authors.initials: E
authors.lastname: Costa
authors.forename: Tânia
authors.initials: T
authors.lastname: Monteiro
authors.forename: Gisela
authors.initials: G
authors.lastname: Silva
authors.forename: Helena
authors.initials: H
authors.lastname: Costa
authors.forename: Ana
authors.initials: A
authors.lastname: Guedes
authors.forename: Inês
authors.initials: I
authors.lastname: Freitas
authors.forename: José
authors.initials: J
authors.lastname: Barbot
mesh_terms: D000743:Anemia, Hemolytic / Q000097:blood / Q000175:diagnosis*; D000751:Anemia, Neonatal / Q000097:blood / Q000175:diagnosis*; D004913:Erythrocytes, Abnormal / Q000473:pathology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn