title: Cytosporone S with antimicrobial activity, isolated from the fungus Trichoderma sp. FKI-6626.
abstract: A new microbial metabolite, cytosporone S (1) was isolated from a fermentation broth of the fungus Trichoderma sp. FKI-6626. Its chemical structure was determined primarily by NMR spectroscopy and mass spectrometry. Compound 1 showed antimicrobial activity against several Gram-positive and Gram-negative bacteria and fungi.
authors.affiliation: Kitasato Institute for Life Sciences, Kitasato University, Tokyo 108-8641, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Ishii
authors.forename: Kenichi
authors.initials: K
authors.lastname: Nonaka
authors.forename: Takuya
authors.initials: T
authors.lastname: Suga
authors.forename: Rokuro
authors.initials: R
authors.lastname: Masuma
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ōmura
authors.forename: Kazuro
authors.initials: K
authors.lastname: Shiomi
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D001578:Benzopyrans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D005658:Fungi / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D014242:Trichoderma / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D001578:Benzopyrans; C581842:cytosporone S