title: [Cultivation of continuous cell lines on the substrate of carbon nanotubes and the effect of electric stimulation on cell proliferation].
abstract: It was demonstrated that the three studied samples of carbon nanotubes of domestic production fixed on the substrate surface did not have toxic effect and could be used for cell cultivation. A biocompatible conductive coating based on carbon nanotubes and bovine serum albumin was developed. The efficacy of the coating for growing in vitro cell cultures was tested. A device was developed for electric stimulation of the cells. Local electric potential was applied to the cells using nanoscale electrodes. The results of human embryonic fibroblast cultivation in a pulsed electric field on conductive nanocomposite substrates were presented. An 26% increase in the proliferative activity of cells was observed at potentials up to 100 mV.
authors.forename: R Ia
authors.initials: RIa
authors.lastname: Podcherniaeva
authors.forename: I A
authors.initials: IA
authors.lastname: Suetina
authors.forename: G R
authors.initials: GR
authors.lastname: Mikhaĭlova
authors.forename: O A
authors.initials: OA
authors.lastname: Lopatina
authors.forename: I I
authors.initials: II
authors.lastname: Bobrinetskiĭ
authors.forename: R A
authors.initials: RA
authors.lastname: Morozov
authors.forename: A S
authors.initials: AS
authors.lastname: Seleznev
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry / Q000633:toxicity; D002417:Cattle; D002460:Cell Line / Q000187:drug effects / Q000528:radiation effects; D049109:Cell Proliferation / Q000187:drug effects / Q000528:radiation effects; D004558:Electric Stimulation; D004560:Electricity; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects; D006801:Humans; D037742:Nanotubes, Carbon / Q000737:chemistry / Q000633:toxicity; D012710:Serum Albumin, Bovine / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D037742:Nanotubes, Carbon; D012710:Serum Albumin, Bovine