title: A novel multifunctional nano-platform with enhanced anti-cancer and photoacoustic imaging modalities using gold-nanorod-filled silica nanobeads.
abstract: The novel nano-seaurchin structure is characteristic of high-density and well-dispersed gold nanorods in one mesoporous silica nanobead. This nanoplatform provided increased photothermal stability, stable photoacoustic signal and highly efficient hyperthermia effect both in vitro and in vivo, indicating a powerful theranostic modality.
authors.affiliation: Department of Materials Sciences and Engineering, National Chiao Tung University, Hsinchu, 300, Taiwan.
authors.forename: Po-Jung
authors.initials: PJ
authors.lastname: Chen
authors.forename: Shang-Hsiu
authors.initials: SH
authors.lastname: Hu
authors.forename: Chih-Tai
authors.initials: CT
authors.lastname: Fan
authors.forename: Meng-Lin
authors.initials: ML
authors.lastname: Li
authors.forename: You-Yin
authors.initials: YY
authors.lastname: Chen
authors.forename: San-Yuan
authors.initials: SY
authors.lastname: Chen
authors.forename: Dean-Mo
authors.initials: DM
authors.lastname: Liu
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D006046:Gold / Q000737:chemistry / Q000627:therapeutic use*; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods; D051379:Mice; D008819:Mice, Nude; D043942:Nanotubes / Q000737:chemistry* / Q000648:ultrastructure; D009369:Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000628:therapy*; D010789:Phototherapy / Q000379:methods; D012822:Silicon Dioxide / Q000737:chemistry / Q000627:therapeutic use*; D014463:Ultrasonography
chemical_list: D006046:Gold; D012822:Silicon Dioxide