title: [Comparison of body weight loss in gastrectomy patients who underwent only surgery and those who underwent surgery followed up with S-1 adjuvant chemotherapy].
abstract: BACKGROUND
  Body weight loss is a common outcome in patients with gastric cancer who have undergone gastrectomy. However, the rate of body weight loss after surgery is unknown.
  
  
  METHODS
  In this retrospective study, we selected patients who underwent radical gastrectomy for gastric cancer and were diagnosed with Stage II or III disease. Further, we compared the body weight loss after surgery between patients in the surgery alone group and the S-1 adjuvant chemotherapy group.
  
  
  RESULTS
  We evaluated 163 patients, of which 81 underwent only surgery, and 82 underwent surgery followed up with S-1 adjuvant chemotherapy. The body weight loss rate at 1, 3, and 6 months in the surgery alone group were 93.1%, 92.9%, and 94.9%, while those in the S-1 adjuvant group were 92.9%, 90.4%,and 91.9%, which was a significant difference.
  
  
  CONCLUSIONS
  Body weight loss after gastrectomy was higher in the S-1 adjuvant group than in the surgery alone group. Further, nutritional support is required for these patients to maintain body weight after surgery.
authors.affiliation: Dept. of Gastrointestinal Surgery, Kanagawa Cancer Center, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Aoyama
authors.forename: Takaki
authors.initials: T
authors.lastname: Yoshikawa
authors.forename: Junya
authors.initials: J
authors.lastname: Shirai
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Hayashi
authors.forename: Takashi
authors.initials: T
authors.lastname: Ogata
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Cho
authors.forename: Norio
authors.initials: N
authors.lastname: Yukawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Oshima
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Rino
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Ozawa
authors.forename: Yuichi
authors.initials: Y
authors.lastname: Kitani
authors.forename: Hiroo
authors.initials: H
authors.lastname: Wada
authors.forename: Munetaka
authors.initials: M
authors.lastname: Masuda
authors.forename: Akira
authors.initials: A
authors.lastname: Tsuburaya
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008875:Middle Aged; D010094:Oxonic Acid / Q000627:therapeutic use*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000601:surgery; D005641:Tegafur / Q000627:therapeutic use*; D015431:Weight Loss
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid