title: Omics strategies for revealing Yersinia pestis virulence.
abstract: Omics has remarkably changed the way we investigate and understand life. Omics differs from traditional hypothesis-driven research because it is a discovery-driven approach. Mass datasets produced from omics-based studies require experts from different fields to reveal the salient features behind these data. In this review, we summarize omics-driven studies to reveal the virulence features of Yersinia pestis through genomics, trascriptomics, proteomics, interactomics, etc. These studies serve as foundations for further hypothesis-driven research and help us gain insight into Y. pestis pathogenesis.
authors.affiliation: Beijing Institute of Microbiology and Epidemiology Beijing, China. ruifuyang@gmail.com
authors.forename: Ruifu
authors.initials: R
authors.lastname: Yang
authors.forename: Zongmin
authors.initials: Z
authors.lastname: Du
authors.forename: Yanping
authors.initials: Y
authors.lastname: Han
authors.forename: Lei
authors.initials: L
authors.lastname: Zhou
authors.forename: Yajun
authors.initials: Y
authors.lastname: Song
authors.forename: Dongsheng
authors.initials: D
authors.lastname: Zhou
authors.forename: Yujun
authors.initials: Y
authors.lastname: Cui
mesh_terms: D000818:Animals; D023281:Genomics / Q000379:methods; D006801:Humans; D055432:Metabolomics / Q000379:methods; D040901:Proteomics / Q000379:methods; D014774:Virulence; D015010:Yersinia pestis / Q000472:pathogenicity*