title: Synthesis of P-stereogenic phospholene boranes via asymmetric deprotonation and ring-closing metathesis.
abstract: The first examples of the asymmetric synthesis of P-stereogenic vinylic phospholene boranes are described. The synthetic approach is concise and flexible. The route involves (i) asymmetric deprotonation-allylation of a dimethyl phosphine borane; (ii) telescoped regioselective deprotonation, paraformaldehyde trapping, and hydroxyl group elimination to give a diene; and (iii) ring-closing metathesis.
authors.affiliation: Department of Chemistry, University of York, Heslington, York YO10 5DD, UK.
authors.forename: Xiao
authors.initials: X
authors.lastname: Wu
authors.forename: Peter
authors.initials: P
authors.lastname: O'Brien
authors.forename: Simon
authors.initials: S
authors.lastname: Ellwood
authors.forename: Francesco
authors.initials: F
authors.lastname: Secci
authors.forename: Brian
authors.initials: B
authors.lastname: Kelly