title: Solubility relationships in binary mixtures of hemoglobin variants Application to the "gelationrd of sickle-cell hemoglobin.
abstract: A thermodynamic treatment of solubility in binary mixtures of hemoglobin variants is presented. It is shown that the reported dependence of the minimum gelling concentration in five binary mixtures of the variants S, C(Harlem') Korle-Bu and A may be satisfactorily accounted for using the derived solubility relations together with simple models relating structure to interaction energies in the condensed phase.
authors.affiliation: Laboratory of Biophysical Chemistry, National Institute of Arthritis, Metabolism, and Digestive Diseases, National Institutes of Health, Bethesda, Maryland 20014, USA.
authors.forename: A P
authors.initials: AP
authors.lastname: Minton