title: Highly sensitive detection of hydrogen peroxide based on nanoporous Fe₂O₃/CoO composites.
abstract: Nanoporous (NP) Fe₂O₃/CoO composites were straightforwardly fabricated by a simple dealloying strategy. Electron microscopy characterization demonstrates that selectively etching FeCoAl ternary alloy in a low concentration of NaOH solution generates a nanoparticle structure with a typical diameter around 80 nm. Interestingly, these nanoparticles consist of open three-dimensional bicontinuous nanosponge structure with uniform pore and ligament distribution around 10 nm. The resulted sample is confirmed to be a mixture of Fe₂O₃ and CoO species based on X-ray photoelectron spectroscopy and X-Ray diffraction analysis. Without any activation pretreatment, NP-Fe₂O₃/CoO composites exhibit excellent electro-oxidation activity toward H₂O₂, such as an excellent sensing performance in a wide linear sensing region from 0.05 to 4.85 mM H₂O₂, fast amperometric response (<2s), and a lower detection limit to 0.1 μM. Along with these attractive features, the as-made composites also behave as a good anti-interference towards glucose, uric acid, dopamine, and ascorbic acid during H₂O₂ detection. Furthermore, the H₂O₂ biosensor based on NP-Fe₂O₃/CoO composites also exhibits excellent long-term stability and reproducibility.
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China.
authors.forename: Jinping
authors.initials: J
authors.lastname: Wang
authors.forename: Hua
authors.initials: H
authors.lastname: Gao
authors.forename: Fenglei
authors.initials: F
authors.lastname: Sun
authors.forename: Qin
authors.initials: Q
authors.lastname: Hao
authors.forename: Caixia
authors.initials: C
authors.lastname: Xu
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D003035:Cobalt / Q000737:chemistry; D006861:Hydrogen Peroxide / Q000737:chemistry / Q000302:isolation & purification*; D007501:Iron / Q000737:chemistry; D057230:Limit of Detection; D053761:Nanocomposites / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry; D012680:Sensitivity and Specificity
chemical_list: D010087:Oxides; D003035:Cobalt; D006861:Hydrogen Peroxide; D007501:Iron