title: Pediatric glioblastoma multiforme: A single-institution experience.
abstract: BACKGROUND
  Glioblastoma multiforme (GBM) is the most common astrocytoma in adults and has a poor prognosis, with a median survival of about 12 months. But, it is rare in children. We report our experience on the pediatric population (20 years or younger) with GBM.
  
  
  METHODS
  Twenty-three patients with GBM who were treated at our hospital during 1990-2008 were evaluated.
  
  
  RESULTS
  The mean age was 15.2 years, and the majority of them (14/23) were male. All had received radiotherapy and some had also received chemotherapy. The mean survival was 16.0 months. Two cases survived more than 5 years. Age, radiation dose and performance status were significantly related to survival.
  
  
  CONCLUSIONS
  GBM in pediatric patients were not very common in our center, and prognosis was unfavorable.
authors.affiliation: Department of Radiation Oncology, Student Research Committee, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: Mansour
authors.initials: M
authors.lastname: Ansari
authors.forename: Hamid
authors.initials: H
authors.lastname: Nasrolahi
authors.forename: Amir-Abbas
authors.initials: AA
authors.lastname: Kani
authors.forename: Mohammad
authors.initials: M
authors.lastname: Mohammadianpanah
authors.forename: Niloofar
authors.initials: N
authors.lastname: Ahmadloo
authors.forename: Shapour
authors.initials: S
authors.lastname: Omidvari
authors.forename: Ahmad
authors.initials: A
authors.lastname: Mosalaei