title: Acute resistance training affects cell surface markers for apoptosis and migration in CD4⁺ and CD8⁺ lymphocytes.
abstract: The purpose of the present study was to examine the acute effects of resistance training (RT) on CD4⁺ and CD8⁺ T lymphocytes apoptosis (annexin V⁺) and migration (CX₃CR1). Twelve subjects performed two RT sessions (3 sets of 9 exercises) with 1 min (Hyper-1) and 3 min (Hyper-3) of rest-interval length between sets and exercises. CD4⁺ and CD8⁺ cells count displayed no change following Hyper-1 and Hyper-3. There was an increase in the percentage of CD4⁺ positive for annexin V⁺ and CX₃CR1⁺ immediately after and 24 h post Hyper-1. Percentage of CD4⁺ positive for annexin V⁺ increased 2 and 24 h post Hyper-3, and decreased after CXCR1⁺ for the same time-points. There was an increase in CD8⁺ positive for annexin V⁺ and CX₃CR1⁺ immediately after, 2 and 24 h post Hyper-1 and Hyper-3, while no differences were found between Hyper-1 and Hyper-3. Acute RT increase the apoptosis and migration of CD4⁺ and CD8⁺ lymphocytes even 24h after exercise, with minimal effects of rest-interval length.
authors.affiliation: Programa de Pós-Graduação em Ciências, Fisiológicas da Universidade Federal de São Carlos, São Carlos, São Paulo, Brazil. guifisiologia@gmail.com
authors.forename: G B
authors.initials: GB
authors.lastname: Pereira
authors.forename: J
authors.initials: J
authors.lastname: Prestes
authors.forename: R A
authors.initials: RA
authors.lastname: Tibana
authors.forename: G E
authors.initials: GE
authors.lastname: Shiguemoto
authors.forename: J
authors.initials: J
authors.lastname: Navalta
authors.forename: S E A
authors.initials: SE
authors.lastname: Perez
mesh_terms: D017304:Annexin A5 / Q000032:analysis / Q000276:immunology; D000954:Antigens, Surface; D017209:Apoptosis; D015415:Biomarkers / Q000032:analysis; D016516:CD4-CD8 Ratio; D015496:CD4-Positive T-Lymphocytes / Q000166:cytology / Q000276:immunology / Q000502:physiology*; D018414:CD8-Positive T-Lymphocytes / Q000166:cytology / Q000276:immunology / Q000502:physiology*; D000073883:CX3C Chemokine Receptor 1; D002465:Cell Movement; D005260:Female; D006801:Humans; D008213:Lymphocyte Activation; D018655:Lymphocyte Count; D008297:Male; D019707:Receptors, Chemokine / Q000032:analysis; D055070:Resistance Training; D055815:Young Adult
chemical_list: D017304:Annexin A5; D000954:Antigens, Surface; D015415:Biomarkers; D000073883:CX3C Chemokine Receptor 1; C095235:CX3CR1 protein, human; D019707:Receptors, Chemokine