title: A case of familial transmission of community-acquired methicillin-resistant Staphylococcus aureus carrying the Inu(A) gene in Santa Fe city, Argentina.
abstract: Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is increasingly recognized as an important pathogen causing skin and soft tissue infections as well as necrotizing pneumonia. We describe a case of familial transmission of CA-MRSA between a 6-month-old boy and his mother in Santa Fe City, Argentina. Both isolates showed an identical antimicrobial susceptibility profile, carried type IV SCCmec and harboured the pvl and the lnu(A) genes. Isolates showed indistinguishable SmaI-PFGE patterns confirming their genetic relationship. These results corroborate the intrafamilial transmission of CA-MRSA and might associate this strain with the repetitive events of furunculosis within the family.
authors.affiliation: Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Ciudad Universitaria, Paraje El Pozo (3000), Santa Fe. emendez@fbcb.unl.edu.ar
authors.forename: Emilce de Los A
authors.initials: Ede L
authors.lastname: Méndez
authors.forename: María L
authors.initials: ML
authors.lastname: Roldán
authors.forename: María R
authors.initials: MR
authors.lastname: Baroni
authors.forename: María A
authors.initials: MA
authors.lastname: Mendosa
authors.forename: Sabrina A
authors.initials: SA
authors.lastname: Cristóbal
authors.forename: Stella M
authors.initials: SM
authors.lastname: Virgolini
authors.forename: Diego
authors.initials: D
authors.lastname: Faccone
mesh_terms: D001118:Argentina; D001426:Bacterial Proteins / Q000235:genetics*; D017714:Community-Acquired Infections; D006801:Humans; D007223:Infant; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000235:genetics*; D013203:Staphylococcal Infections / Q000635:transmission*; D014504:Urban Health
chemical_list: D001426:Bacterial Proteins