title: Leukaemia cutis in chronic lymphocytic leukaemia following varicella zoster virus reactivation.
abstract: We report a case of a 75-year-old male with indolent chronic lymphocytic leukaemia (CLL) for 8 years, who presented with a 6-month history of a painful, zosteriform eruption in a T3-4 distribution that evolved into an unusual crop of papular nodules. Upon biopsy and immunostaining of these lesions CLL was proven consistent with leukaemia cutis related to varicella-zoster virus reactivation. In the absence of other treatment indices, he was commenced on chlorambucil with successful resolution of both his pain and the lesions.
authors.affiliation: Department of Clinical Haematology, Alfred Hospital, Commercial Road, Melbourne, VIC 3181, Australia. greghapgood@hotmail.com
authors.forename: G
authors.initials: G
authors.lastname: Hapgood
authors.forename: E
authors.initials: E
authors.lastname: Mooney
authors.forename: H V
authors.initials: HV
authors.lastname: Dinh
authors.forename: D
authors.initials: D
authors.lastname: Gin
authors.forename: C
authors.initials: C
authors.lastname: McLean
authors.forename: S B
authors.initials: SB
authors.lastname: Ting
mesh_terms: D000368:Aged; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D002699:Chlorambucil / Q000627:therapeutic use; D018450:Disease Progression; D006562:Herpes Zoster / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy / Q000473:pathology*; D017254:Leukemic Infiltration / Q000150:complications*; D008297:Male; D012867:Skin / Q000473:pathology*; D017193:Skin Diseases, Viral
chemical_list: D018906:Antineoplastic Agents, Alkylating; D002699:Chlorambucil