title: The postsaccadic unreliability of gain fields renders it unlikely that the motor system can use them to calculate target position in space.
abstract: Gain fields, the eye-position modulation of visual responses, are thought to provide a mechanism by which the motor system can accurately calculate target position in space despite a constantly moving eye. Current gain-field models assume that the modulation of visual responses by eye position is accurate at all times, even around the time of a saccade. Here, we show that for at least 150 ms after a saccade, gain fields in the lateral intraparietal area (LIP) are unreliable. The majority of LIP cells with steady-state gain fields reflect the presaccadic eye position. The remainder of the cells have responses that cannot be predicted by their steady-state gain fields. Nonetheless, a monkey's oculomotor performance is accurate during this time. These results suggest that current models built upon a simple gain-field algorithm cannot be used to calculate the position of a target in space that flashes briefly after a saccade.
authors.affiliation: Mahoney-Keck Center for Brain and Behavior Research, Department of Neuroscience, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA. ben.yixing.xu@gmail.com
authors.forename: Benjamin Y
authors.initials: BY
authors.lastname: Xu
authors.forename: Carine
authors.initials: C
authors.lastname: Karachi
authors.forename: Michael E
authors.initials: ME
authors.lastname: Goldberg
mesh_terms: D000818:Animals; D005073:Evoked Potentials, Somatosensory; D005133:Eye Movements / Q000502:physiology*; D005403:Fixation, Ocular / Q000502:physiology*; D007699:Kinesthesis / Q000502:physiology; D008253:Macaca mulatta; D008297:Male; D008959:Models, Neurological; D010775:Photic Stimulation; D012032:Refractory Period, Electrophysiological / Q000502:physiology*; D015203:Reproducibility of Results; D012438:Saccades / Q000502:physiology*; D014793:Visual Cortex / Q000502:physiology