title: Epidermodysplasia verruciformis: an unusual malignant transformation.
abstract: Epidermodysplasia verruciformis (EV) is a rare, life-long heritable disease caused due to a unique susceptibility to human papilloma virus. The disseminated verrucous lesions and pityriasis versicolor-like lesions persist from early childhood and can transform into a cutaneous malignancy in a fourth of patients. Malignant transformation into syringoid eccrine carcinoma (SEC) has been reported only once so far. SEC is an extremely invasive, rare, locally destructive, slowly growing adnexal tumor. We hereby report the association of EV with SEC in a 29-year-old male.
authors.affiliation: Department of Skin & VD, GSMC & KEM Hospital, Parel, Mumbai, India.
authors.forename: Prachi G
authors.initials: PG
authors.lastname: Agrawal
authors.forename: Sunanda A
authors.initials: SA
authors.lastname: Mahajan
authors.forename: Uday S
authors.initials: US
authors.lastname: Khopkar
authors.forename: Vidya D
authors.initials: VD
authors.lastname: Kharkar
mesh_terms: D000328:Adult; D018280:Carcinoma, Skin Appendage / Q000150:complications / Q000473:pathology*; D002471:Cell Transformation, Neoplastic; D004819:Epidermodysplasia Verruciformis / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D027383:Papillomaviridae; D013544:Sweat Gland Neoplasms / Q000150:complications / Q000473:pathology*