title: [A case of recurrent gastric cancer responding to CPT-11].
abstract: A 68-year-old man underwent total gastrectomy for gastric cancer(Stage II). Adjuvant chemotherapy with S-1 was administered. At 21 months after the operation, he received a nephron catheter because of hydronephrosis caused by para-aortic lymph node metastases. Then, weekly paclitaxel was given as a second-line treatment. However, his tumor marker level increased and he therefore received CPT-11 (160 mg/m2) as a third-line treatment at 28 months after the operation. At 7 days after the first CPT-11 administration, he was hospitalized because of a severe adverse event involving nausea and general fatigue, which caused a continuous fever of 39°C and renal failure at 14 days after administration. However, hydration enabled him to recover several days later. Computed tomography scan revealed the lymph node metastases to be partial remission.
authors.affiliation: Dept. of Surgery, Hasuda Hospital, Japan.
authors.forename: Kumi
authors.initials: K
authors.lastname: Hasegawa
authors.forename: Eriko
authors.initials: E
authors.lastname: Katsuta
authors.forename: Noriko
authors.initials: N
authors.lastname: Iwata
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Aoyagi
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Yoshida
authors.forename: Jun
authors.initials: J
authors.lastname: Kaneko
authors.forename: Shizuaki
authors.initials: S
authors.lastname: Maejima
authors.forename: Jun
authors.initials: J
authors.lastname: Isogai
mesh_terms: D000368:Aged; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use*; D002166:Camptothecin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005743:Gastrectomy; D006801:Humans; D000077146:Irinotecan; D008207:Lymphatic Metastasis; D008297:Male; D012008:Recurrence; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D000077146:Irinotecan; D002166:Camptothecin