title: Per-6-amino-β-cyclodextrin as a chiral base catalyst promoting one-pot asymmetric synthesis of 2-aryl-2,3-dihydro-4-quinolones.
abstract: A highly efficient one-pot synthesis of enantiomerically enriched 2-aryl-2,3-dihydroquinolin-4(1H)-ones has been carried out for the first time using per-6-ABCD as a supramolecular host, chiral base catalyst, and a reusable promoter to give the corresponding scaffold with high yield (up to 99%) and enantiomeric excess (up to 99%). The catalyst is recovered and reused without loss in its activity.
authors.affiliation: School of Chemistry, Madurai Kamaraj University, Madurai 625021, India.
authors.forename: Kuppusamy
authors.initials: K
authors.lastname: Kanagaraj
authors.forename: Kasi
authors.initials: K
authors.lastname: Pitchumani
mesh_terms: D042462:4-Quinolones / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D013237:Stereoisomerism; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D042462:4-Quinolones; D047392:beta-Cyclodextrins; C534165:per-6-amino-beta-cyclodextrin