title: Increasing off-time improves sleep-disordered breathing induced by vagal nerve stimulation.
abstract: Vagal nerve stimulation (VNS) has been reported to adversely impact breathing in sleep. While continuous positive airway pressure is often employed to treat these patients, little data exist on the effects of adjusting various settings on VNS-induced sleep-disordered breathing. We describe a patient in whom increasing off-time caused resolution of VNS-induced arterial oxygen desaturations in sleep, which we believe is a novel observation.
authors.affiliation: Seton Hall University, Edison, NJ, USA. sbhat2012@yahoo.com
authors.forename: Sushanth
authors.initials: S
authors.lastname: Bhat
authors.forename: Liudmila
authors.initials: L
authors.lastname: Lysenko
authors.forename: Eli S
authors.initials: ES
authors.lastname: Neiman
authors.forename: Gautami K
authors.initials: GK
authors.lastname: Rao
authors.forename: Sudhansu
authors.initials: S
authors.lastname: Chokroverty
mesh_terms: D004827:Epilepsy / Q000628:therapy*; D006801:Humans; D008297:Male; D017286:Polysomnography; D012891:Sleep Apnea Syndromes / Q000209:etiology*; D055536:Vagus Nerve Stimulation / Q000009:adverse effects* / Q000379:methods; D055815:Young Adult