title: [Staging of non-small cell lung cancer using CT and integrated PET-CT].
abstract: BACKGROUND
  Lung cancer is the leading cause of death from cancer in developed countries. Radiological imaging methods are the basic methods in early diagnosis of this disease. TNM classification is a very important tool for optimal treatment in non-small lung cancer (NSCLC). Conventional radiological techniques allow the evaluation of the stage on the basis of anatomical changes only, while PET-CT provides information about the biochemical processes that may precede anatomical changes. The aim of this study was to compare the accuracy and sensitivity of CT and PET-CT in the staging of NSCLC.
  
  
  METHODS
  The study was conducted on a group of 99 patients with NSCLC diagnosed at the Institute of Tuberculosis and Lung Diseases in the period from January 2008 to May 2010. CT and PET-CT were performed in all patients. Histological or cytological examination of the material obtained from biopsy, bronchoscopy, mediastinoscopy, and intraoperatively was the reference test. TNM classification was performed independently after CT and PET-CT.
  
  
  CONCLUSIONS
  It has been shown that PET-CT is a more accurate and sensitive method than CT in the staging process in NSCLC. PET-CT allowed the correct classification of the T, N, M, and total TNM in, respectively, 97%, 95%, 99%, and 89% of cases, while for CT it was, respectively, 95%, 84%, 84%, and 68% (p = 0.0002).
authors.affiliation: Zakład Radiologii Instytutu Gruźlicy i Chorób Płuc w Warszawie. ucyna.opoka@wp.pl
authors.forename: Lucyna
authors.initials: L
authors.lastname: Opoka
authors.forename: Jolanta
authors.initials: J
authors.lastname: Kunikowska
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Podgajny
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Błasińska-Przerwa
authors.forename: Barbara
authors.initials: B
authors.lastname: Burakowska
authors.forename: Karina
authors.initials: K
authors.lastname: Oniszh
authors.forename: Magdalena
authors.initials: M
authors.lastname: Gola
authors.forename: Renata
authors.initials: R
authors.lastname: Langfort
authors.forename: Piotr
authors.initials: P
authors.lastname: Rudziński
authors.forename: Iwona
authors.initials: I
authors.lastname: Bestry
authors.forename: Kazimierz
authors.initials: K
authors.lastname: Roszkowski-Śliż
mesh_terms: D000328:Adult; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis* / Q000473:pathology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D009367:Neoplasm Staging; D011044:Poland; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D019275:Radiopharmaceuticals