title: Experience of pediatric stroke from a tertiary medical center in North India.
abstract: OBJECTIVE
  The etiology and outcome of pediatric stroke differs in different geographical regions and there is no comprehensive study from India. This study evaluates the etiology, type and predictors of outcome of pediatric stroke from Northern India.
  
  
  METHODS
  79 stroke patients aged 1month to 18years managed during 2001-2011 were retrospectively analyzed. Their mean age was 144.8months (0.6-18years) and 26 were females. Detailed history including stroke risk factors was noted. The clinical, imaging and laboratory findings were recorded. Stroke was classified as per neuroimaging findings. The predictors of death were evaluated by multivariate analysis.
  
  
  RESULTS
  62 (78.5%) patients had arterial ischemic stroke (AIS), 10 (12.7%) intracerebral hemorrhage (ICH) and 7 (8.9%) had cerebral venous sinus thrombosis (CVST). The underlying etiology was neuroinfections in 25, cardioembolic in 9, prothrombotic conditions in 5, arteriopathy in 4, arterial dissection in 3, mitochondrial cytopathy and cervical rib in 1 each and cryptogenic in 13 patients. 7 patients died. On multivariate analysis death was related to level of consciousness on admission.
  
  
  CONCLUSIONS
  AIS is more common than ICH in this study and 8.9% patients died. Infection is the most common cause of pediatric stroke in Northern India which is amenable to therapy and is preventable.
authors.affiliation: Department of Neurology, Sanjay Gandhi Post Graduate Medical Sciences, Lucknow, India.
authors.forename: Jayantee
authors.initials: J
authors.lastname: Kalita
authors.forename: Gourav
authors.initials: G
authors.lastname: Goyal
authors.forename: Usha Kant
authors.initials: UK
authors.lastname: Misra
mesh_terms: D000293:Adolescent; D000784:Aortic Dissection / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke / Q000175:diagnosis* / Q000453:epidemiology* / Q000628:therapy; D062606:Tertiary Care Centers / Q000639:trends*