title: Comparison of echocardiography with dual-source computed tomography for assessment of left ventricular volume in healthy Beagles.
abstract: OBJECTIVE
  To compare echocardiographic measurements of left ventricular (LV) volume obtained via a modified Simpson or Teichholz method with those obtained via dual-source CT (DSCT).
  
  
  METHODS
  7 healthy Beagles.
  
  
  METHODS
  Each dog was anesthetized for DSCT; LV volume was determined from contrast-enhanced images of the LV lumen during all phases of contraction. Echocardiography was performed with dogs awake and anesthetized. End-diastolic volume (EDV), end-systolic volume (ESV), stroke volume, and ejection fraction were measured via a modified Simpson method and Teichholz method. Each dog was anesthetized twice with a 1-week interval between anesthetic sessions.
  
  
  RESULTS
  Results obtained while dogs were anesthetized revealed that the modified Simpson method underestimated LV volume (mean ± SD EDV, 24.82 ± 2.38 mL; ESV, 12.24 ± 1.77 mL), compared with that estimated by the Teichholz method (EDV, 32.57 ± 2.85 mL; ESV, 14.87 ± 2.09 mL) or DSCT (EDV, 34.14 ± 1.57 mL; ESV, 16.71 ± 0.76 mL). Ejection fraction (modified Simpson method, 48.53% ± 4.24%; Teichholz method, 54.33% ± 4.26%; DSCT, 51.00% ± 2.71%) differed significantly among the 3 methods. Echocardiographic results obtained while dogs were awake revealed that EDV, ESV, and stroke volume differed significantly between the modified Simpson and Teichholz methods.
  
  
  CONCLUSIONS
  LV volume determined via the Teichholz method was more similar to that determined via DSCT than was the LV volume determined via the modified Simpson method. The modified Simpson method underestimated LV volume, compared with that obtained via the Teichholz method, in both anesthetized and awake dogs.
authors.affiliation: Departments of Veterinary Radiology and Diagnostic Imaging, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.
authors.forename: Miyoung
authors.initials: M
authors.lastname: Lee
authors.forename: Nohwon
authors.initials: N
authors.lastname: Park
authors.forename: Seungyeon
authors.initials: S
authors.lastname: Lee
authors.forename: Ahra
authors.initials: A
authors.lastname: Lee
authors.forename: Joohyun
authors.initials: J
authors.lastname: Jung
authors.forename: Youngjun
authors.initials: Y
authors.lastname: Kim
authors.forename: Sungmin
authors.initials: S
authors.lastname: Ko
authors.forename: Hwiyool
authors.initials: H
authors.lastname: Kim
authors.forename: Soonwuk
authors.initials: S
authors.lastname: Jeong
authors.forename: Kidong
authors.initials: K
authors.lastname: Eom
mesh_terms: D000818:Animals; D004285:Dogs / Q000502:physiology*; D004452:Echocardiography / Q000379:methods* / Q000662:veterinary; D005260:Female; D008297:Male; D061330:Multidetector Computed Tomography / Q000379:methods* / Q000662:veterinary; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D014057:Tomography, X-Ray Computed / Q000379:methods* / Q000662:veterinary; D016277:Ventricular Function, Left