title: [A case of early gastric cancer with cervical lymph nodes recurrence 5 years after a curative resection].
abstract: A 61-year-old man exhibiting epigastric malaise on hunger was diagnosed with early gastric cancer by upper gastrointestinal endoscopy. Since no obvious metastasis was recognized by abdominal computed tomography(CT), he underwent distal gastrectomy with D1+ lymphadenectomy. Histopathological examination revealed a pStage IA lesion[pT1a (m), pN0]. He received no adjuvant chemotherapy, and he remained alive and in good health without recurrence for more than 5 years. At 5 years and 7 months after gastrectomy, he noticed cervical lymph node swelling and underwent further examination. He was diagnosed with recurrent gastric cancer in cervical lymph nodes, and treatment with S-1 (120 mg/ day) was initiated. He remained alive and free of progression for approximately 1 year on S-1 therapy, but he suddenly died from disseminated intravascular coagulation without an obvious cause. We report a rare case of late recurrence after curative resection in a patient treated for early gastric cancer.
authors.affiliation: Dept. of Surgical Oncology, Osaka City University Graduate School of Medicine, Japan.
authors.forename: Kazuya
authors.initials: K
authors.lastname: Muguruma
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Tanaka
authors.forename: Katsunobu
authors.initials: K
authors.lastname: Sakurai
authors.forename: Kenjirou
authors.initials: K
authors.lastname: Kimura
authors.forename: Hisashi
authors.initials: H
authors.lastname: Nagahara
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Amano
authors.forename: Eiji
authors.initials: E
authors.lastname: Noda
authors.forename: Naoshi
authors.initials: N
authors.lastname: Kubo
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Maeda
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Sawada
authors.forename: Masaichi
authors.initials: M
authors.lastname: Ohira
authors.forename: Kosei
authors.initials: K
authors.lastname: Hirakawa
mesh_terms: D001706:Biopsy; D003131:Combined Modality Therapy; D004211:Disseminated Intravascular Coagulation / Q000150:complications; D004338:Drug Combinations; D017809:Fatal Outcome; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000628:therapy; D009367:Neoplasm Staging; D010094:Oxonic Acid / Q000627:therapeutic use; D012008:Recurrence; D013274:Stomach Neoplasms / Q000150:complications / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005641:Tegafur / Q000627:therapeutic use; D013997:Time Factors
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid