title: High resolution dynamic cardiac MRI using partial separability of spatiotemporal signals with a novel sampling scheme.
abstract: The partial separability (PS) of spatiotemporal signals has been exploited to accelerate dynamic cardiac MRI by sampling two datasets (training and imaging datasets) without breath-holding or ECG triggering. According to the theory of partially separable functions, the wider the range of spatial frequency components covered by the training dataset, the more accurate the temporal constraint imposed by the PS model. Therefore, it is necessary to develop a new sampling scheme for the PS model in order to cover a wider range of spatial frequency components. In this paper, we propose the use of radial sampling trajectories for collecting the training dataset and Cartesian sampling trajectories for collecting the imaging dataset. In vivo high resolution cardiac MRI experiments demonstrate that the proposed data sampling scheme can significantly improve the image quality. The image quality using the PS model with the proposed sampling scheme is comparable to that of a commercial method using retrospective cardiac gating and breath-holding. The success of this study demonstrates great potential for high-quality, high resolution dynamic cardiac MRI without ECG gating or breath-holding through use of the PS model and the novel data sampling scheme.
authors.affiliation: Shenzhen Key Lab for MRI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.
authors.forename: Guoxi
authors.initials: G
authors.lastname: Xie
authors.forename: Xiang
authors.initials: X
authors.lastname: Feng
authors.forename: Anthony G
authors.initials: AG
authors.lastname: Christodoulou
authors.forename: Dehe
authors.initials: D
authors.lastname: Weng
authors.forename: Xin
authors.initials: X
authors.lastname: Liu
authors.forename: Bensheng
authors.initials: B
authors.lastname: Qiu
mesh_terms: D000465:Algorithms; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000295:instrumentation / Q000379:methods*; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D018401:Sample Size; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D062211:Spatio-Temporal Analysis