title: Raltegravir can be used safely in HIV-1-infected patients treated with warfarin.
abstract: Drug co-administration often affects the patient response to warfarin through various mechanisms. We describe here five HIV-1-infected patients on treatment with warfarin in whom the use of raltegravir was associated with a favourable outcome.
authors.affiliation: AIDS Clinical Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku Tokyo 162-8655, Japan. hhonda@acc.ncgm.go.jp
authors.forename: H
authors.initials: H
authors.lastname: Honda
authors.forename: H
authors.initials: H
authors.lastname: Gatanaga
authors.forename: T
authors.initials: T
authors.lastname: Aoki
authors.forename: K
authors.initials: K
authors.lastname: Watanabe
authors.forename: H
authors.initials: H
authors.lastname: Yazaki
authors.forename: J
authors.initials: J
authors.lastname: Tanuma
authors.forename: K
authors.initials: K
authors.lastname: Tsukada
authors.forename: M
authors.initials: M
authors.lastname: Honda
authors.forename: K
authors.initials: K
authors.lastname: Teruya
authors.forename: Y
authors.initials: Y
authors.lastname: Kikuchi
authors.forename: S
authors.initials: S
authors.lastname: Oka
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use*; D000925:Anticoagulants / Q000627:therapeutic use; D004347:Drug Interactions; D015658:HIV Infections / Q000097:blood* / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011760:Pyrrolidinones / Q000627:therapeutic use*; D000068898:Raltegravir Potassium; D016896:Treatment Outcome; D014859:Warfarin / Q000627:therapeutic use*
chemical_list: D019380:Anti-HIV Agents; D000925:Anticoagulants; D011760:Pyrrolidinones; D000068898:Raltegravir Potassium; D014859:Warfarin