title: [Immunotherapy with hyperthermia for advanced or recurrent breast cancer patients in whom standard therapy showed no effect or was refused].
abstract: We treated 168 advanced or recurrent breast cancer patients with hyperthermia or immunotherapy (2005/7-2011/12). In these cases, standard therapy showed no effect or was refused. Clinical benefit( complete response: CR, partial response, and long stable disease) was observed in 26 cases; CR occurred in 4 cases. The effective rate of immunotherapy increased from 9.1% to 23.9% using hyperthermia. Both hyperthermia and immunotherapy needed to be used together to be effective in 20 cases with distant metastases to solid organs.
authors.affiliation: Osaka Cancer Immuno-Chemotherapy Center, Osaka, Japan.
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Takeda
authors.forename: Takashi
authors.initials: T
authors.lastname: Takeda
authors.forename: Shogo
authors.initials: S
authors.lastname: Kobayashi
authors.forename: Hiroko
authors.initials: H
authors.lastname: Takeda
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D007167:Immunotherapy; D008875:Middle Aged; D012008:Recurrence