title: Obesity-related hypertension and its remission following gastric bypass surgery - a review of the mechanisms and predictive factors.
abstract: It is well established that hypertension and obesity appear to be associated. The exact mechanism by which they are linked is unclear and remains a topic of a great deal of research. Current NICE guidelines recommend that patients with a BMI in excess of 35 kg/m(2) should be considered for bariatric surgery if they have a concomitant obesity-associated condition, of which hypertension is one. The commonest bariatric procedure in the UK is the Roux-en-Y gastric bypass, which has been shown to result in long-standing remission of hypertension in up to 93% of patients. This paper summarizes the existing literature on the main theories as to how obesity leads to hypertension as well as the literature concerning the effects of gastric bypass surgery on hypertension.
authors.affiliation: Department of General Surgery, York Hospital, Wigginton Road, York YO318HE, UK. rpbgt@hotmail.com
authors.forename: Simon Timothy
authors.initials: ST
authors.lastname: Adams
authors.forename: Mohamed
authors.initials: M
authors.lastname: Salhab
authors.forename: Zeiad Ihsan
authors.initials: ZI
authors.lastname: Hussain
authors.forename: Glenn V
authors.initials: GV
authors.lastname: Miller
authors.forename: Stephen H
authors.initials: SH
authors.lastname: Leveson
mesh_terms: D015992:Body Mass Index; D015390:Gastric Bypass / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D009765:Obesity / Q000150:complications* / Q000601:surgery*