title: Cryptic and asymptomatic Opisthorchis felineus infections.
abstract: We describe the diagnostic difficulties experienced during an opisthorchiasis outbreak. Of 31 infected individuals, 61.3% were asymptomatic, and in the 12 symptomatic individuals, the duration of non-pathognomonic symptoms was shorter than 4 weeks. Serology by enzyme-linked immunosorbent assay and polymerase chain reaction fecal analysis were shown to be the most sensitive diagnostic tools.
authors.affiliation: Unità Operativa Complessa Malattie Infettive, Belcolle Hospital, Viterbo, Italy. armignacco@asl.vt.it
authors.forename: Orlando
authors.initials: O
authors.lastname: Armignacco
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Ferri
authors.forename: Maria Angeles
authors.initials: MA
authors.lastname: Gomez-Morales
authors.forename: Luciano
authors.initials: L
authors.lastname: Caterini
authors.forename: Edoardo
authors.initials: E
authors.lastname: Pozio
mesh_terms: D000328:Adult; D000368:Aged; D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D018509:DNA, Helminth / Q000235:genetics; D004196:Disease Outbreaks; D004305:Dose-Response Relationship, Drug; D005243:Feces / Q000737:chemistry / Q000469:parasitology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008297:Male; D008463:Mebendazole / Q000627:therapeutic use; D008875:Middle Aged; D009889:Opisthorchiasis / Q000175:diagnosis* / Q000188:drug therapy; D009891:Opisthorchis / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D011223:Praziquantel / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D018509:DNA, Helminth; D007074:Immunoglobulin G; D011223:Praziquantel; D008463:Mebendazole; D015766:Albendazole