title: Elements of regiocontrol in the direct heteroarylation of indoles/pyrroles: synthesis of bi- and fused polycyclic heteroarenes by twofold or tandem fourfold C-H activation.
abstract: Cross-coupling: the "chelation-directed control" and "catalytic-system-based control" strategies effectively switch the C2/C3-site selectivity in the heteroarylation of indoles and pyrroles with N-heteroarenes by a palladium-catalyzed twofold C-H activation to form biheteroarenes and are further extended to the synthesis of complex fused tri- and tetracyclic heteroarenes by a tandem fourfold C-H activation.
authors.affiliation: Key Laboratory of Green Chemistry and Technology of the Ministry of Education, College of Chemistry, West China Medical School, Sichuan University, Chengdu, PR China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wang
authors.forename: Feijie
authors.initials: F
authors.lastname: Song
authors.forename: Yinsong
authors.initials: Y
authors.lastname: Zhao
authors.forename: Yumin
authors.initials: Y
authors.lastname: Huang
authors.forename: Lei
authors.initials: L
authors.lastname: Yang
authors.forename: Dongbing
authors.initials: D
authors.lastname: Zhao
authors.forename: Jingbo
authors.initials: J
authors.lastname: Lan
authors.forename: Jingsong
authors.initials: J
authors.lastname: You