title: [A case of advanced gastric cancer with esophageal severe dysplasia resected after neoadjuvant S-1+cisplatin therapy].
abstract: A 72-year-old man was admitted to our hospital complaining of upper abdominal pain and back pain. Advanced gastric cancer was found at the fundus of the stomach, and severe dysplasia was found at the lower esophagus. We proceeded with neoadjuvant chemotherapy (S-1+CDDP) because the lymph nodes in the lesser curvature of the stomach were metastasized and invasion of the pancreas and some vessels was suspected by computed tomography. The tumor size was reduced remarkably, the esophageal dysplasia disappeared after preoperative chemotherapy, and we were able to perform total gastrectomy.
authors.affiliation: Dept. of Surgery, Fukuoka Tokushukai Medical Center, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Umemoto
authors.forename: Seiji
authors.initials: S
authors.lastname: Hosaka
authors.forename: Takashi
authors.initials: T
authors.lastname: Kikutake
authors.forename: Shouichi
authors.initials: S
authors.lastname: Okubo
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Maeno
authors.forename: Kazuo
authors.initials: K
authors.lastname: Inada
authors.forename: Shuji
authors.initials: S
authors.lastname: Nagao
authors.forename: Shunji
authors.initials: S
authors.lastname: Kawamoto
authors.forename: Takahisa
authors.initials: T
authors.lastname: Yoshida
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D004338:Drug Combinations; D004938:Esophageal Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005743:Gastrectomy; D006801:Humans; D008297:Male; D020360:Neoadjuvant Therapy; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy* / Q000473:pathology; D010094:Oxonic Acid / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005641:Tegafur / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D002945:Cisplatin