title: Dairy product consumption, calcium intakes, and metabolic syndrome-related factors over 5 years in the STANISLAS study.
abstract: OBJECTIVE
  We assessed the associations of total dairy products; milk, yogurt, and cottage cheese; cheese; and calcium with 5-y changes in components of the metabolic syndrome.
  
  
  METHODS
  Two hundred eighty-eight men and 300 women 28 to 60 y of age from the suivi temporaire annuel non invasif de la santé des lorrains assurés sociaux (STANISLAS) cohort completed at baseline a 3-d dietary record. Statistics were performed using multivariate regression analysis.
  
  
  RESULTS
  In men, no relation was found between the four dietary indices and components of the metabolic syndrome measured at baseline. Conversely, the consumption of milk, yogurt, and cottage cheese at entry was inversely associated with 5-y changes in glucose levels (P ≤ 0.05, P ≤ 0.01 for sex interaction) and positively with 5-y changes in high-density lipoprotein cholesterol (P ≤ 0.05). Higher calcium intakes were significantly related to a lower 5-y increase of the body mass index (BMI) and waist circumference in men (P ≤ 0.01, P ≤ 0.05 for sex interaction). In addition, changes in diastolic blood pressure were inversely associated with the consumption of milk, yogurt, and cottage cheese only in men with a normal BMI (P ≤ 0.05 for BMI interaction). In women, unlike men, associations were shown for some components measured at baseline: total dairy positively related to BMI and waist circumference; total dairy, milk, yogurt, and cottage cheese, and calcium were positively related to triacylglycerols and negatively to high-density lipoprotein cholesterol. However, no significant association was found for any 5-y-changes.
  
  
  CONCLUSIONS
  In men only, a higher consumption of dairy products was associated with positive changes in the metabolic profile in a 5-y period; a higher calcium consumption was associated with a lower 5-y increase of the BMI and waist circumference.
authors.affiliation: EA 4373 "Génétique Cardiovasculaire", Faculté de Pharmacie, Université de Lorraine, Nancy, France.
authors.forename: Anastasia
authors.initials: A
authors.lastname: Samara
authors.forename: Bernard
authors.initials: B
authors.lastname: Herbeth
authors.forename: Ndeye Coumba
authors.initials: NC
authors.lastname: Ndiaye
authors.forename: Fréderic
authors.initials: F
authors.lastname: Fumeron
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Billod
authors.forename: Gérard
authors.initials: G
authors.lastname: Siest
authors.forename: Sophie
authors.initials: S
authors.lastname: Visvikis-Siest
mesh_terms: D000328:Adult; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D015992:Body Mass Index; D002136:Calcium, Dietary / Q000008:administration & dosage*; D008076:Cholesterol, HDL / Q000097:blood; D015331:Cohort Studies; D003611:Dairy Products; D004032:Diet; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000517:prevention & control; D008875:Middle Aged; D008892:Milk; D012737:Sex Factors; D055105:Waist Circumference; D015014:Yogurt
chemical_list: D001786:Blood Glucose; D002136:Calcium, Dietary; D008076:Cholesterol, HDL