title: [Methods for the protection against counterfeit medications. Part 2. The assessment of interlot dispersion of the metoprolol succinate tablets fabricated by different manufacturers].
abstract: This paper reports the results of analysis of the metoprolol succinate tablets fabricated by two different manufacturers, Akrikhin (Russia) and AstraZeneka (Sweden) by near-IR spectroscopy in the combination with the chemometric processing of the data obtained (discriminative analysis). It is concluded that this method is applicable for the assessment of interlot dispersion of the metoprolol succinate tablets.
authors.forename: V A
authors.initials: VA
authors.lastname: Iakushev
authors.forename: M A
authors.initials: MA
authors.lastname: Morozova
authors.forename: T E
authors.initials: TE
authors.lastname: Elizarova
authors.forename: S B
authors.initials: SB
authors.lastname: Fitilev
authors.forename: T V
authors.initials: TV
authors.lastname: Pletneva
mesh_terms: D002138:Calibration; D002626:Chemistry, Pharmaceutical; D058110:Counterfeit Drugs / Q000032:analysis*; D016002:Discriminant Analysis; D008790:Metoprolol / Q000031:analogs & derivatives* / Q000032:analysis / Q000592:standards; D010602:Pharmacopoeias as Topic; D011786:Quality Control; D012426:Russia; D019265:Spectroscopy, Near-Infrared / Q000295:instrumentation / Q000379:methods*; D013548:Sweden; D013607:Tablets
chemical_list: D058110:Counterfeit Drugs; D013607:Tablets; D008790:Metoprolol