title: Exfoliation syndrome in Nigeria.
abstract: OBJECTIVE
  The purpose of this study was to estimate the prevalence of exfoliation syndrome (XFS) and its association with ocular disease in patients attending the eye clinic of the University College Hospital (UCH) in Ibadan, Nigeria.
  
  
  METHODS
  A total of 448 consecutive new patients, aged 30-90 years who presented to the eye clinic of UCH between December 2009 and November 2010 were evaluated. Each patient had a complete ophthalmic examination. Patients with exfoliative material on the anterior lens surface and/or pupillary margin in either or both eyes were considered to have XFS. Means, standard deviation, and 95% confidence intervals were calculated.
  
  
  RESULTS
  All the patients examined were from the southern part of Nigeria. Majority (94.2%) were of the Yoruba tribe from southwestern Nigeria, while 5.8% were from southeastern Nigeria. The mean age of the study cohort was 58.5 ± 13.8, 54.8% were males, 12 (2.7%) had XFS. All patients with XFS were of the Yoruba tribe, with a mean age 65.6 ± 5.6 years. There was a male predilection (66.7%). All eyes with XFS had lenticular opacities. XFS was bilateral in eight patients (66.7%) of whom seven patients (87.5%) had glaucoma and lenticular opacities bilaterally.
  
  
  CONCLUSIONS
  This is the first report of the existence of XFS in Nigeria. Larger studies are necessary in this population to further investigate the disease.
authors.affiliation: Department of Ophthalmology, University College Hospital, Ibadan, Nigeria.
authors.forename: Olusola O
authors.initials: OO
authors.lastname: Olawoye
authors.forename: Adeyinka O
authors.initials: AO
authors.lastname: Ashaye
authors.forename: Christopher C
authors.initials: CC
authors.lastname: Teng
authors.forename: Jeffrey M
authors.initials: JM
authors.lastname: Liebmann
authors.forename: Robert
authors.initials: R
authors.lastname: Ritch
authors.forename: Benedict G
authors.initials: BG
authors.lastname: Ajayi
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D016001:Confidence Intervals; D017889:Exfoliation Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence; D012189:Retrospective Studies; D017678:Sex Distribution; D014065:Tonometry, Ocular