title: Radiotherapy supports protective tumor-specific immunity.
abstract: Radiotherapy is an important therapeutic option for the treatment of cancer. Growing evidence indicates that, besides inducing an irreversible DNA damage, radiotherapy promotes tumor-specific immune response, which significantly contribute to therapeutic efficacy. We postulate that radiotherapy activates tumor-associated dendritic cells, thus changing the tolerogenic tumor environment into an immunogenic one.
authors.affiliation: Department of Oncology; University Hospital Zurich; Zurich, Switzerland.
authors.forename: Anurag
authors.initials: A
authors.lastname: Gupta
authors.forename: Anu
authors.initials: A
authors.lastname: Sharma
authors.forename: Lotta
authors.initials: L
authors.lastname: von Boehmer
authors.forename: Laura
authors.initials: L
authors.lastname: Surace
authors.forename: Alexander
authors.initials: A
authors.lastname: Knuth
authors.forename: Maries
authors.initials: M
authors.lastname: van den Broek