title: [Antiretroviral therapy with three nucleoside reverse transcriptase inhibitors in treatment-naive HIV-infected patients in Abidjan (Cote d'Ivoire)].
abstract: This study assesses the results of initial antiretroviral therapy with 3 nucleoside reverse transcriptase inhibitors over the first 12 months of treatment. Patients' general health improved significantly during the year, with a significant mean weight gain (from 59.3 kg to 65.12 kg) and a strong regression in the frequency of opportunistic infections over the study period, from 38% to 2% (P<0.0001). The mean CD4 T-cell count rose from 242.8 to 390.5 cell/mm(3), for a mean increase of 147.7 cells/mm(3). Accordingly, antiretroviral treatment with three nucleoside reverse transcriptase inhibitors is effective and is a useful alternative in a country with limited resources.
authors.forename: F B
authors.initials: FB
authors.lastname: Sako
authors.forename: J
authors.initials: J
authors.lastname: Zoungrana
authors.forename: J P
authors.initials: JP
authors.lastname: Dembélé
authors.forename: N A
authors.initials: NA
authors.lastname: Kassi
authors.forename: S I
authors.initials: SI
authors.lastname: Ouattara
mesh_terms: D000328:Adult; D000368:Aged; D007560:Cote d'Ivoire; D015224:Dideoxynucleosides / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D019259:Lamivudine / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018894:Reverse Transcriptase Inhibitors / Q000627:therapeutic use*; D055815:Young Adult; D015215:Zidovudine / Q000008:administration & dosage*; D000099227:Abacavir
chemical_list: D015224:Dideoxynucleosides; D019259:Lamivudine; D018894:Reverse Transcriptase Inhibitors; D015215:Zidovudine; D000099227:Abacavir