title: [Hepatic arterial infusion with subsequent hepatectomy for a sigmoid colon cancer patient with hepatic metastases-a case report].
abstract: It is common to use systemic chemotherapy, instead of hepatic arterial infusion (HAI) of 5-fluorouracil (5-FU) or other cytotoxic agents, for unresectable hepatic metastases in colorectal cancer patients. Nevertheless, systemic administration of anticancer agents such as FOLFOX or FOLFIRI is sometimes difficult to continue for infirm patients. A 71-year-old female who had undergone sigmoidectomy for sigmoid colon cancer received HAI for 12 months because of big bilobar hepatic metastases and poor performance status. Thereafter, a two-stage hepatectomy(first, left lobe: second, S7+8 and S5) was performed successfully. She has been alive for 2.5 years after the first operation but with two small lung metastases in the left lobe. Because of bad performance status and her weak social and familial conditions, treatment with standard systemic chemotherapy could not be continued. In such cases, HAI should be performed if the metastases are limited to the liver.
authors.affiliation: Dept. of Surgery, Tokyo Metropolitan Health and Medical Treatment Corporation, Japan.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ando
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Kurokawa
authors.forename: Hideaki
authors.initials: H
authors.lastname: Ganno
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Watayo
authors.forename: Akira
authors.initials: A
authors.lastname: Fukuda
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nagahama
authors.forename: Katsunori
authors.initials: K
authors.lastname: Ami
authors.forename: Jun
authors.initials: J
authors.lastname: Takasaki
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Amagasa
authors.forename: Ryota
authors.initials: R
authors.lastname: Seki
authors.forename: Keiichi
authors.initials: K
authors.lastname: Fujiya
authors.forename: Kuniyoshi
authors.initials: K
authors.lastname: Arai
authors.forename: Shikofumi
authors.initials: S
authors.lastname: Tei
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Okada
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D006498:Hepatectomy; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary / Q000601:surgery; D012811:Sigmoid Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery
chemical_list: D000970:Antineoplastic Agents