title: [The activity of enzymes in lymphocytes of children and adults with chronic viral hepatitis B and C].
abstract: It is established that in patients with chronic viral hepatitis B and C the intensity of reaction is increased in lymphocytes of children as compared with adults. The study also established the limitation of turning out of substrates for macromolecular synthesis and the decrease of activity of reactions of tricarbonic acid cycle at the expense of decreasing of substrates flow from amino-acid metabolism included. Under chronic hepatitis C, in lymphocytes the levels of activity of enzymes involved in functioning of main metabolic paths and glutathione system of antioxidant defense of are decreased in children as compared with adults.
authors.forename: V G
authors.initials: VG
authors.lastname: Bulygin
authors.forename: E P
authors.initials: EP
authors.lastname: Tikhonova
authors.forename: G V
authors.initials: GV
authors.lastname: Bulygin
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D016174:Hepacivirus / Q000472:pathogenicity; D006515:Hepatitis B virus / Q000472:pathogenicity; D019694:Hepatitis B, Chronic / Q000097:blood / Q000201:enzymology; D019698:Hepatitis C, Chronic / Q000097:blood / Q000201:enzymology; D006801:Humans; D008214:Lymphocytes / Q000201:enzymology*