title: The level of evidence 5 blues: investigating medicine when experience trumps equipoise.
authors.forename: Hans A
authors.initials: HA
authors.lastname: Puttgen
authors.forename: Marek A
authors.initials: MA
authors.lastname: Mirski
mesh_terms: D000707:Anaphylaxis / Q000188:drug therapy*; D000818:Animals; D002545:Brain Ischemia / Q000517:prevention & control*; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D004837:Epinephrine / Q000627:therapeutic use*; D008297:Male; D008751:Methylene Blue / Q000627:therapeutic use*; D009569:Nitric Oxide / Q000037:antagonists & inhibitors*; D014662:Vasoconstrictor Agents / Q000627:therapeutic use*
chemical_list: D004791:Enzyme Inhibitors; D014662:Vasoconstrictor Agents; D009569:Nitric Oxide; D008751:Methylene Blue; D004837:Epinephrine