title: [Four cases of airway obstruction successfully treated by airway stenting].
abstract: We report 4 cases of malignant airway obstruction treated by airway stenting. Three cases were caused by esophageal cancer and the fourth case by malignant lymphoma. Two patients with esophageal cancer received chemoradiotherapy after airway stenting and survived for 24 months and 54 months, respectively (without cancer recurrence). One patient with esophageal cancer died of airway bleeding 2 months after stent placement. The malignant lymphoma patient was treated by cyclophosphamide+doxorubicin+vincristine+prednisolone(CHOP) with rituximab. Airway obstruction due to malignancy is an urgent oncological situation that should be treated immediately. Airway stenting shows a marked and immediate improvement in dyspnea. Consequently, the induction of chemoradiotherapy or chemotherapy is possible. Two patients were successfully treated by chemoradiotherapy, of which 1 survived for more than 4 years without any evidence of cancer recurrence. Additional chemoradiotherapy for patients who receive esophageal stenting is controversial because of the high frequency of adverse events. However, chemoradiotherapy after airway stenting may demonstrate acceptable anti-cancer effects with fewer adverse events. Airway stenting was an effective treatment for airway obstruction, and additional treatment is essential for longer survival.
authors.affiliation: Dept. of Surgery, Tokyo Metropolitan Health and Medical Corporation, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nagahama
authors.forename: Katsunori
authors.initials: K
authors.lastname: Ami
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nakamura
authors.forename: Keiichi
authors.initials: K
authors.lastname: Fujiya
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Watayo
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Amagasa
authors.forename: Jun
authors.initials: J
authors.lastname: Takasaki
authors.forename: Hideaki
authors.initials: H
authors.lastname: Ganno
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Kurokawa
authors.forename: Akira
authors.initials: A
authors.lastname: Fukuda
authors.forename: Masayuki
authors.initials: M
authors.lastname: Ando
authors.forename: Kuniyoshi
authors.initials: K
authors.lastname: Arai
mesh_terms: D000328:Adult; D000368:Aged; D000402:Airway Obstruction / Q000209:etiology / Q000628:therapy*; D004938:Esophageal Neoplasms / Q000150:complications; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000150:complications; D008297:Male; D015607:Stents; D014057:Tomography, X-Ray Computed