title: Pregnancies in women with uterine malformation, treated obstruction of hemivagina and ipsilateral renal agenesis.
abstract: OBJECTIVE
  The aim of this study was to evaluate the outcome of pregnancies in women who had uterine malformation and surgically treated obstructed hemivagina with ipsilateral renal agenesis.
  
  
  METHODS
  The study group comprised 21 women with malformed uterus (12 didelphic, 6 septate and 3 bicornuate uterus). All of them had a history of surgical excision of the longitudinal vaginal septum caused obstructed hemivagina and ipsilateral renal agenesis. All pregnancies and possible surgical interventions were evaluated during the follow-up period (median 13.2 years).
  
  
  RESULTS
  Thirteen out of 21 women attempting pregnancy conceived. They produced 22 pregnancies, 17 (77 %) were contralateral to the treated obstructed hemivagina and unilateral renal agenesis. The median interval between surgical treatment of obstructed hemivagina and the first pregnancy was 10.5 years. Twenty (91 %) pregnancies ended in delivery of a living infant. Preeclampsia (14 %), preterm delivery (36 %), high frequency (38 %) of fetal breech presentation and the cesarean section rate (67 %) were found.
  
  
  CONCLUSIONS
  Accurate diagnosis and appropriate surgery to open an obstructed hemivagina in adolescence assure fertility. Preterm birth is associated with malformed uterus and unilateral renal agenesis may predispose to preeclampsia.
authors.affiliation: Department of Obstetrics and Gynecology, Tampere University Hospital Medical School, University of Tampere, 33014, Tampere, Finland. pentti.heinonen@uta.fi
authors.forename: Pentti K
authors.initials: PK
authors.lastname: Heinonen
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D000013:Congenital Abnormalities; D005260:Female; D005865:Gestational Age; D006399:Hematocolpos / Q000209:etiology / Q000601:surgery; D006801:Humans; D007668:Kidney / Q000002:abnormalities; D007674:Kidney Diseases / Q000150:complications / Q000151:congenital*; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D016896:Treatment Outcome; D014599:Uterus / Q000002:abnormalities*; D014621:Vagina / Q000002:abnormalities* / Q000601:surgery*; D014623:Vaginal Diseases / Q000601:surgery*; D055815:Young Adult