title: Coverage, context and targeted prevention: optimising our impact.
abstract: Development of efficacious interventions is only the first step in achieving population level impact. Efficacious interventions impact infection levels in the population only if they are implemented at the right scale. Coverage must be prioritised across subpopulations based on the diversity and clustering of infections and risk in society, and expanded rapidly without delay. It is important to prioritise those who are most likely to transmit infection first.
authors.affiliation: Division of STD Prevention, The National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, Atlanta, GA 30333, USA. SAral@cdc.gov
authors.forename: Sevgi O
authors.initials: SO
authors.lastname: Aral
authors.forename: Willard
authors.initials: W
authors.lastname: Cates
mesh_terms: D000225:Adenine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D002944:Circumcision, Male; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000068679:Emtricitabine; D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D006292:Health Priorities; D006801:Humans; D008297:Male; D063065:Organophosphonates / Q000627:therapeutic use*; D012725:Sexual Behavior / Q000706:statistics & numerical data*; D000068698:Tenofovir; D014481:United States / Q000453:epidemiology; D014622:Vaginal Creams, Foams, and Jellies
chemical_list: D019380:Anti-HIV Agents; D063065:Organophosphonates; D014622:Vaginal Creams, Foams, and Jellies; D003841:Deoxycytidine; D000068698:Tenofovir; D000068679:Emtricitabine; D000225:Adenine