title: Th1 cell induction in lymph nodes according to a red-blue chemokine map.
abstract: Lymph nodes are compartmentalized organs but whether this feature has a role in T cell differentiation has been unclear. In this issue, Groom et al. (2012) reveal that spatially separated expression of two CXCR3 ligands guides Th1 cell development.
authors.affiliation: Division of Rheumatology, Department of Medicine, and Rosalind Russell Medical Research Center for Arthritis, University of California-San Francisco, CA 94143, USA. mehrdad.matloubian@ucsf.edu
authors.forename: Mehrdad
authors.initials: M
authors.lastname: Matloubian
authors.forename: Jason G
authors.initials: JG
authors.lastname: Cyster