title: In vitro effects of a novel polysaccharide from the seeds of Plantago asiatica L. on intestinal function.
abstract: Effects of a novel polysaccharide (PLP) from the seeds of Plantago asiatica L. on intestinal function were investigated in vitro. Results showed that PLP had notable influence on slowing down glucose diffusion and inhibiting α-amylase activity. These might help prolong blood glucose response and hence control the postprandial glucose concentration. PLP could also decrease pancreatic lipase and protease activities, which may help lower the levels of serum lipids and modify protein digestibility. In addition, PLP was able to bind bile acids and may reduce cholesterol level. These results suggested that PLP may have potential benefits for human intestinal function and might be used as a potential ingredient in functional food applications.
authors.affiliation: State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.
authors.forename: Jie-Lun
authors.initials: JL
authors.lastname: Hu
authors.forename: Shao-Ping
authors.initials: SP
authors.lastname: Nie
authors.forename: Chang
authors.initials: C
authors.lastname: Li
authors.forename: Ming-Yong
authors.initials: MY
authors.lastname: Xie
mesh_terms: D000818:Animals; D001647:Bile Acids and Salts / Q000378:metabolism; D002417:Cattle; D002784:Cholesterol / Q000378:metabolism; D004058:Diffusion; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007422:Intestines / Q000187:drug effects* / Q000502:physiology*; D008049:Lipase / Q000378:metabolism; D008823:Micelles; D010179:Pancreas / Q000187:drug effects / Q000201:enzymology; D010447:Peptide Hydrolases / Q000378:metabolism; D010943:Plantago / Q000737:chemistry*; D011134:Polysaccharides / Q000494:pharmacology*; D012639:Seeds / Q000737:chemistry*; D034421:Sus scrofa; D000516:alpha-Amylases / Q000378:metabolism
chemical_list: D001647:Bile Acids and Salts; D008823:Micelles; D011134:Polysaccharides; D002784:Cholesterol; D008049:Lipase; D000516:alpha-Amylases; D010447:Peptide Hydrolases; D005947:Glucose