title: Prevalence of Opisthorchis viverrini infection in Nakhon Ratchasima province, Northeast Thailand.
abstract: BACKGROUND
  Opisthorchis viverrini infection is a serious public-health problem in Southeast Asia especially in Lao PDR and Thailand. It is associated with a number of hepatobiliary diseases and the evidence strongly indicates that liver fluke infection is the major etiology of cholangiocarcinoma.
  
  
  OBJECTIVE
  This study aimed to determine actual levels of Opisthorchis viverrini infection in Nakhon Ratchasima province, Northeast Thailand.
  
  
  METHODS
  A cross-sectional survey was conducted during a one year period from October 2010 to September 2011. O. viverrini infection was determined using a modified Kato's thick smear technique and socio-demographic data were collected using predesigned semi-structured questionnaires.
  
  
  RESULTS
  A total of 1,168 stool samples were obtained from 516 males and 652 females, aged 5-90 years. Stool examination showed that 2.48% were infected with O. viverrini. Males were slightly more likely to be infected than females, but the different was not statistically significant. O. viverrini infection was most frequent in the 51-60 year age group and was found to be positively associated with education and occupation. Positive results were evident in 16 of 32 districts, the highest prevalence being found in Non Daeng with 16.7%, followed by Pra Thai with 11.1%, Kaeng Sanam Nang with 8.33%, and Lam Ta Men Chai (8.33%) districts.
  
  
  CONCLUSIONS
  This study indicates that O viverrini is still a problem in some areas of Nakhon Ratchasima, the patients in this study bing suitable for the purpose of monitoring projects.
authors.affiliation: Parasitic Disease Research Unit, Suranaree University of Technology, Muang, Nakorn Rachasima, Thailand.
authors.forename: Soraya J
authors.initials: SJ
authors.lastname: Kaewpitoon
authors.forename: Ratana
authors.initials: R
authors.lastname: Rujirakul
authors.forename: Natthawut
authors.initials: N
authors.lastname: Kaewpitoon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001650:Bile Duct Neoplasms / Q000453:epidemiology* / Q000209:etiology; D001653:Bile Ducts, Intrahepatic / Q000469:parasitology* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D018281:Cholangiocarcinoma / Q000453:epidemiology* / Q000209:etiology; D003430:Cross-Sectional Studies; D005243:Feces / Q000737:chemistry; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009889:Opisthorchiasis / Q000150:complications / Q000453:epidemiology* / Q000469:parasitology; D009891:Opisthorchis; D015995:Prevalence; D011379:Prognosis; D012307:Risk Factors; D013785:Thailand / Q000453:epidemiology; D055815:Young Adult