title: Ruptured intracranial aneurysms in pediatric polyarteritis nodosa: case report.
abstract: Polyarteritis nodosa (PAN) is a rare, systemic necrotizing vasculitis of small and medium size arteries that leads to aneurysms in various organs. Aneurysms associated with PAN are common in visceral arteries, however, intracranial aneurysms are rare, especially in childhood. A pediatric patient with PAN developed serial hemorrhagic strokes from a ruptured superior cerebellar artery aneurysm (subarachnoid hemorrhage) and a de novo aneurysm of the frontoorbital artery (intracerebral hemorrhage) after 9 months. Patients with PAN who present with intracranial aneurysms are candidates for intervention even if the aneurysm is unruptured and still small, and close observation is needed to detect de novo aneurysms in patients with chronic history of PAN.
authors.affiliation: Department of Neurosurgery, National Hospital Organization Nagasaki Medical Center, Ohmura, Nagasaki.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Toyoda
authors.forename: Keisuke
authors.initials: K
authors.lastname: Tsutsumi
authors.forename: Tomohito
authors.initials: T
authors.lastname: Hirao
authors.forename: Tomonori
authors.initials: T
authors.lastname: Ono
authors.forename: Hideaki
authors.initials: H
authors.lastname: Takahata
authors.forename: Keisuke
authors.initials: K
authors.lastname: Toda
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Baba
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ito
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yonekura
mesh_terms: D017542:Aneurysm, Ruptured / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D015901:Angiography, Digital Subtraction; D002531:Cerebellum / Q000098:blood supply*; D002536:Cerebral Arteries / Q000473:pathology / Q000601:surgery; D002648:Child; D003399:Craniotomy; D003937:Diagnosis, Differential; D005260:Female; D005625:Frontal Lobe / Q000098:blood supply*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography; D009460:Neurologic Examination; D010488:Polyarteritis Nodosa / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis / Q000601:surgery; D012086:Reoperation; D014057:Tomography, X-Ray Computed