title: [Antihypertensive therapy in diabetes mellitus - 2012 guidelines of the Austrian Diabetes Association].
abstract: Blood pressure lowering is one of the most important interventions for reducing the vascular complications and mortality in patients with diabetes mellitus. Recent studies indicate that the optimal blood pressure level might be in the range between 130-135 mmHg systolic and 80 mmHg diastolic. Lower blood pressure levels (e.g. 120/80 mmHg) can further reduce the risk for stroke and diabetic nephropathy, but are associated with increased cardiovascular mortality. In particular very low blood pressure levels (< 120 mmHg) should be avoided in patients with coronary heart disease or peripheral arterial disease. Most patients with diabetes mellitus need antihypertensive combination therapies, whereby ACE-inhibitors or Angiotensin-II receptor antagonists should be first line drugs.
authors.affiliation: 1. Medizinische Abteilung, Krankenanstalt Rudolfstiftung, Wien, Österreich. guntram.schernthaner@meduniwien.ac.at
authors.forename: Guntram
authors.initials: G
authors.lastname: Schernthaner
authors.forename: Heinz
authors.initials: H
authors.lastname: Drexel
authors.forename: Alexander R
authors.initials: AR
authors.lastname: Rosenkranz
authors.forename: Gerit-Holger
authors.initials: GH
authors.lastname: Schernthaner
authors.forename: Bruno
authors.initials: B
authors.lastname: Watschinger
mesh_terms: D000959:Antihypertensive Agents / Q000008:administration & dosage*; D001317:Austria; D048909:Diabetes Complications / Q000188:drug therapy* / Q000517:prevention & control*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000209:etiology* / Q000517:prevention & control
chemical_list: D000959:Antihypertensive Agents