title: Etiology and epidemiology of catheter related bloodstream infections in patients receiving home parenteral nutrition in a gastromedical center at a tertiary hospital in denmark.
abstract: We conducted a retrospective epidemiologic study of catheter related bloodstream infections (CRBSI) in patients receiving long-term home parenteral nutrition (HPN) from January 2002 to December 2005. Our results showed that coagulase negative staphylococci (CoNS) were the most prevalent pathogens (44.7% of all CRBSI episodes), followed by Enterobacteriaceae (33.2%). Prevalence for candidemia and Enterococcus bacteremia was relatively high (14.4% and 10.8%, respectively). Cefuroxime resistance was observed in 65.4% CoNS and 31.5% Enterobacteriaceae. Based on the results from the study, a new empiric antimicrobial treatment regiment was suggested.
authors.affiliation: Department of Clinical Microbiology, Slagelse Hospital, Slagelse, Denmark ; Department of Clinical Microbiology, University Hospital of Copenhagen, Denmark.
authors.forename: Xiaohui Chen
authors.initials: XC
authors.lastname: Nielsen
authors.forename: Ming
authors.initials: M
authors.lastname: Chen
authors.forename: Anne-Marie Blok
authors.initials: AM
authors.lastname: Hellesøe
authors.forename: Palle Bekker
authors.initials: PB
authors.lastname: Jeppesen
authors.forename: Jonna
authors.initials: J
authors.lastname: Gyldenlykke
authors.forename: Michael
authors.initials: M
authors.lastname: Tvede
authors.forename: Leif Percival
authors.initials: LP
authors.lastname: Andersen