title: Management of a xeroderma pigmentosum case with oral findings in a dental setup.
abstract: Xeroderma pigmentosum (XP) is heterogeneous group of disorder transmitted as autosomal recessive trait. It is characterised by photosensitivity, freckled pigmentation and premature skin ageing and malignant tumour development. The manifestations are due to a cellular hypersensitivity to ultraviolet light resulting from a defect in DNA repair. Multiple cutaneous neoplasms develop at a young age in persons with XP. Two important causes of mortality are metastatic malignant melanoma and squamous cell carcinoma (SCC). We report a case of XP in a 22 year-old male patient who developed SCC of lower lip with in a short period of 1 month.
authors.affiliation: Department of Oral Medicine and Radiology, Modern Dental College and Research Centre, Indore, Madhya Pradesh, India. drreddybanda@gmail.com
authors.forename: Vanaja Reddy
authors.initials: VR
authors.lastname: Banda
authors.forename: Naveen Reddy
authors.initials: NR
authors.lastname: Banda
authors.forename: Ramesh
authors.initials: R
authors.lastname: Reddy
authors.forename: Praveen
authors.initials: P
authors.lastname: Banda
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000473:pathology*; D006801:Humans; D008047:Lip Diseases / Q000150:complications / Q000473:pathology*; D008048:Lip Neoplasms / Q000150:complications / Q000473:pathology*; D008297:Male; D014983:Xeroderma Pigmentosum / Q000150:complications / Q000473:pathology*; D055815:Young Adult