title: [Serological detection of specific IgE in allergic rhinitis].
abstract: OBJECTIVE
  To investigate the positive rate of allergen-specific serum IgE in local patients with allergic rhinitis, and compare the positive rate of allergen-specific serum IgE across different age groups and between sexes.
  
  
  METHODS
  Inhalant and ingested serum allergen-specific IgE was detected in 145 patients with allergic rhinitis. Patients were grouped by age and sex, and then the positive rate was compared between the two groups.
  
  
  RESULTS
  Ninety-four out of 145 cases had positive allergen specific IgE, and the positive rate was 64.8%. There were 45 cases with single positive allergen, accounting for 47.9%. And there were 49 cases with two or multiple positive allergens, mainly inhalant allergens, accounting for 52.1%. The difference of allergen-specific IgE positive rate between men and women was not statistically significant (P>0.05); but the positive rate between adults and adolescents was statistically significant (P<0.05).
  
  
  CONCLUSIONS
  Inhalant allergen is a major cause of allergic rhinitis in local people. The positive rate of household dust mites and dermatophagoides was highest (87.4%). The positive rate of specific IgE was associated with age, and adolescents have higher positive rate than adults.
authors.affiliation: Department of Otolaryngology, Peking University Shenzhen Hospital, Shenzhen, 518036, China. Kaiym@126.com
authors.forename: Yuemei
authors.initials: Y
authors.lastname: Kai
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000485:Allergens / Q000097:blood*; D000818:Animals; D039741:Antigens, Dermatophagoides / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D008297:Male; D008875:Middle Aged; D039981:Pyroglyphidae; D012189:Retrospective Studies; D065631:Rhinitis, Allergic; D012221:Rhinitis, Allergic, Perennial / Q000097:blood* / Q000453:epidemiology; D016036:Seroepidemiologic Studies
chemical_list: D000485:Allergens; D039741:Antigens, Dermatophagoides; D007073:Immunoglobulin E