title: [Acute miliary tuberculosis or Isambert disease: a case report].
abstract: Pharynx tuberculosis consists in a set of active lesions in granulomatous-type mucosa, resulting from Mycobacterium tuberculosis infection. In an endemic context, this diagnosis should be raised in cases of head and neck disease. A recent observation of a case of acute miliary tuberculosis gave us the opportunity to conduct a literature review of this disorder. This 9-year-old girl presented with dysphagia associated with pharyngeal discomfort, snoring, and hoarseness lasting for 8 months. This pharyngeal syndrome occurred in the context of an impaired general condition. Clinical examination found a diffuse mucosal granulation aspect in the oropharynx. The workup showed an inflammatory syndrome with a strong positive intradermal tuberculin reaction. The biopsy found an aspect of giant cell granuloma with caseous necrosis. The course was favorable on antituberculous chemotherapy. Tuberculosis is a chronic bacterial infection caused by a bacterium belonging to the M. tuberculosis complex. Pharyngeal tuberculosis remains a rare disease, but several epidemiological parameters show an upsurge of this disease, prompting us to report this observation.
authors.affiliation: Service d'ORL et chirurgie cervico-faciale, CHU Mohammed VI, Marrakech, Maroc. ziad.tarik.orl@gmail.com
authors.forename: T
authors.initials: T
authors.lastname: Ziad
authors.forename: H
authors.initials: H
authors.lastname: Nouri
authors.forename: A
authors.initials: A
authors.lastname: Adny
authors.forename: Y
authors.initials: Y
authors.lastname: Rochdi
authors.forename: L
authors.initials: L
authors.lastname: Aderdour
authors.forename: A
authors.initials: A
authors.lastname: Raji
mesh_terms: D000208:Acute Disease; D000995:Antitubercular Agents / Q000627:therapeutic use; D001706:Biopsy; D002648:Child; D003680:Deglutition Disorders / Q000382:microbiology; D003937:Diagnosis, Differential; D005260:Female; D006685:Hoarseness / Q000382:microbiology; D006801:Humans; D010608:Pharyngeal Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D035583:Rare Diseases; D012913:Snoring / Q000382:microbiology; D016896:Treatment Outcome; D014374:Tuberculin Test; D014391:Tuberculosis, Miliary / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents