title: Cell height: Tao rising.
abstract: During oogenesis in Drosophila melanogaster, the cells in the follicular epithelium of the ovary undergo a transition from a cuboidal to a squamous shape. In this issue, Gomez et al. (2012. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201207150) show that the kinase Tao promotes the endocytosis of the cell adhesion molecule Fasciclin 2 from the lateral surface of the cell and is critical for the cuboidal to squamous cell shape transition. Their results indicate that Tao is rising as a regulator of cell height.
authors.affiliation: State Key Laboratory of Genetic Engineering, Department of Biochemistry, School of Life Sciences, Fudan University, Shanghai 200433, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Cai
authors.forename: Keith E
authors.initials: KE
authors.lastname: Mostov
mesh_terms: D000818:Animals; D015816:Cell Adhesion Molecules, Neuronal / Q000378:metabolism*; D048430:Cell Shape; D029721:Drosophila Proteins / Q000502:physiology*; D004331:Drosophila melanogaster / Q000201:enzymology*; D004705:Endocytosis; D004847:Epithelial Cells / Q000502:physiology*; D005260:Female; D008297:Male; D017346:Protein Serine-Threonine Kinases / Q000502:physiology*
chemical_list: D015816:Cell Adhesion Molecules, Neuronal; D029721:Drosophila Proteins; C051642:fasciclin II; D017346:Protein Serine-Threonine Kinases; C556036:Tao protein, Drosophila