title: Prevalence of hypertension and diabetes and coexistence of chronic kidney disease and cardiovascular risk in the population of the republic of moldova.
abstract: In 2005, the International Society of Nephrology (ISN) established the Global Outreach Program (GO) aimed at building a capacity for detecting and managing chronic kidney disease and its complications in low- and middle-income countries. Here we report data from the 2006-2007 screening program (1025 subjects from the general population) in the Republic of Moldova aimed to determine the prevalence of hypertension, diabetes, and their coexistence with microalbuminuria. The likelihood of a serious cardiovascular (CV) event was also estimated. Hypertension and diabetes were very common among screened subjects. The prevalence of microalbuminuria was 16.9% and that of estimated GFR <60 ml/min/1.73 m(2) (decreased renal function) was 9.4%. Male gender was associated with an increased prevalence of hypertension and microalbuminuria. Hypertension and diabetes clustered in subjects with microalbuminuria and renal dysfunction. Risk factors such as preobesity/obesity, physical inactivity and smoking were relatively common, even in younger participants. The prevalence of subjects with predicted 10-year CV risk ≥10% was 10.0%. In conclusion, in the Republic of Moldova patients with hypertension and diabetes should be screened for the coexistence of renal abnormalities, with the intention of developing disease-specific health-care interventions with the primary goal to reduce CV morbidity and mortality and prevent renal disease progression to end stage renal disease.
authors.affiliation: Republican Clinic Hospital, Chisinau, Moldova.
authors.forename: Igor
authors.initials: I
authors.lastname: Codreanu
authors.forename: Vera
authors.initials: V
authors.lastname: Sali
authors.forename: Sergiu
authors.initials: S
authors.lastname: Gaibu
authors.forename: Luminita
authors.initials: L
authors.lastname: Suveica
authors.forename: Sergiu
authors.initials: S
authors.lastname: Popa
authors.forename: Norberto
authors.initials: N
authors.lastname: Perico
authors.forename: Bogdan
authors.initials: B
authors.lastname: Ene-Iordache
authors.forename: Sergio
authors.initials: S
authors.lastname: Carminati
authors.forename: John
authors.initials: J
authors.lastname: Feehally
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Remuzzi