title: Ascorbyl palmitate-loaded chitosan nanoparticles: characteristic and polyphenol oxidase inhibitory activity.
abstract: The aim of this study was to produce ascorbyl palmitate (AP)-loaded nanoparticles in order to inhibit polyphenol oxidase (PPO) in bananas. AP-loaded chitosan nanoparticles were prepared using acetic acid and citric acid (denoted as CS/AA and CS/CA nanoparticles, respectively). As the initial AP concentration increases, the particle size significantly decreases, and the zeta potential, entrapment and loading efficiency significantly increases. The PPO inhibitory activity of AP was effectively improved when AP was nano-encapsulated by chitosan compared to no encapsulation. These results suggest that chitosan nano-encapsulation can be used to enhance the PPO inhibitory activity of AP.
authors.affiliation: Department of Food and Nutrition, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul 133-791, Republic of Korea.
authors.forename: Mi Kyung
authors.initials: MK
authors.lastname: Kim
authors.forename: Ji-Soo
authors.initials: JS
authors.lastname: Lee
authors.forename: Kwang Yup
authors.initials: KY
authors.lastname: Kim
authors.forename: Hyeon Gyu
authors.initials: HG
authors.lastname: Lee
mesh_terms: D019342:Acetic Acid / Q000737:chemistry; D001205:Ascorbic Acid / Q000031:analogs & derivatives* / Q000494:pharmacology; D004156:Catechol Oxidase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D048271:Chitosan / Q000737:chemistry*; D019343:Citric Acid / Q000737:chemistry; D028521:Musa / Q000201:enzymology*; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D055672:Static Electricity
chemical_list: D019343:Citric Acid; D048271:Chitosan; D004156:Catechol Oxidase; D001205:Ascorbic Acid; D019342:Acetic Acid; C031226:6-O-palmitoylascorbic acid