title: Dose conformation to the spine during palliative treatments using dynamic wedges.
abstract: Radiation therapy is commonly used to alleviate pain associated with metastatic disease of the spine. Often, isodose lines are manipulated using dynamic or physical wedges to encompass the section of spine needing treatment while minimizing dose to normal tissue. We will compare 2 methods used to treat the entire thoracic spine. The first method treats the thoracic spine with a single, nonwedged posterior-anterior (PA) field. Dose is prescribed to include the entire spine. Isodose lines tightly conform to the top and bottom vertebrae, but vertebrae between these 2 received more than enough coverage. The second method uses a combination of wedges to create an isodose line that mimics the curvature of the thoracic spine. This "C"-shaped curvature is created by overlapping 2 fields with opposing dynamic wedges. Machine constraints limit the treatment length and therefore 2 isocenters are used. Each of the 2 PA fields contributes a portion of the total daily dose. This technique creates a "C"-shaped isodose line that tightly conforms to the thoracic spine, minimizing normal tissue dose. Spinal cord maximum dose is reduced, as well as mean dose to the liver, esophagus, and heart.
authors.affiliation: West Texas Cancer Center at Medical Center Hospital, Odessa, TX 79761, USA. Matthew.Ormsby@usoncology.com
authors.forename: Matthew A
authors.initials: MA
authors.lastname: Ormsby
authors.forename: R Craig
authors.initials: RC
authors.lastname: Herndon
authors.forename: Joseph G
authors.initials: JG
authors.lastname: Kaczor
mesh_terms: D059350:Chronic Pain / Q000209:etiology / Q000517:prevention & control*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D010166:Palliative Care / Q000379:methods*; D011874:Radiometry / Q000379:methods; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D020266:Radiotherapy, Conformal / Q000295:instrumentation* / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013125:Spinal Neoplasms / Q000150:complications / Q000532:radiotherapy*; D013904:Thoracic Vertebrae / Q000528:radiation effects*