title: Cylindroma of head and neck: review of the literature and report of two rare cases.
abstract: Cylindromas are very rare and benign adnexal tumours of the skin. Very few reports of these benign tumours are reported in the literature. Dermal cylindromas are characterised as a benign neoplasm of the eccrine sweat glands. The most frequent location is the head and neck. Multiple occurrences are often linked to the Brooke-Spiegler syndrome. The Brooke-Spiegler syndrome is inherited as an irregular autosomal dominant trait. A malignant transformation to an adenoid cystic carcinoma is also described in the literature. The leading treatment modality described in the literature is the complete surgical removal of the lesions. Here, a systematic review of the literature is presented with two rare cases of cylindromas.
authors.affiliation: Department for Cranio- and Maxillofacial Surgery, Heinrich-Heine-University Düsseldorf, Germany. damandeep.singh@med.uni-duesseldorf.de
authors.forename: Daman Deep
authors.initials: DD
authors.lastname: Singh
authors.forename: Christian
authors.initials: C
authors.lastname: Naujoks
authors.forename: Rita
authors.initials: R
authors.lastname: Depprich
authors.forename: Klaus-Werner
authors.initials: KW
authors.lastname: Schulte
authors.forename: Frank
authors.initials: F
authors.lastname: Jankowiak
authors.forename: Norbert R
authors.initials: NR
authors.lastname: Kübler
authors.forename: Jörg
authors.initials: J
authors.lastname: Handschel
mesh_terms: D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005153:Facial Neoplasms / Q000175:diagnosis; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009386:Neoplastic Syndromes, Hereditary / Q000175:diagnosis; D012535:Scalp / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis*; D016038:Skin Transplantation / Q000379:methods; D050151:Subcutaneous Fat / Q000473:pathology; D013524:Surgical Flaps / Q000637:transplantation