title: A common structure for the potexviruses.
abstract: We have used fiber diffraction, cryo-electron microscopy, and scanning transmission electron microscopy to confirm the symmetry of three potexviruses, potato virus X, papaya mosaic virus, and narcissus mosaic virus, and to determine their low-resolution structures. All three viruses have slightly less than nine subunits per turn of the viral helix. Our data strongly support the view that all potexviruses have approximately the same symmetry. The structures are dominated by a large domain at high radius in the virion, with a smaller domain, which includes the putative RNA-binding site, extending to low radius.
authors.affiliation: Department of Biological Sciences and Center for Structural Biology, Vanderbilt University, Nashville, TN 37235, USA.
authors.forename: Amy
authors.initials: A
authors.lastname: Kendall
authors.forename: Wen
authors.initials: W
authors.lastname: Bian
authors.forename: Alexander
authors.initials: A
authors.lastname: Maris
authors.forename: Caitlin
authors.initials: C
authors.lastname: Azzo
authors.forename: Joseph
authors.initials: J
authors.lastname: Groom
authors.forename: Dewight
authors.initials: D
authors.lastname: Williams
authors.forename: Jian
authors.initials: J
authors.lastname: Shi
authors.forename: Phoebe L
authors.initials: PL
authors.lastname: Stewart
authors.forename: Joseph S
authors.initials: JS
authors.lastname: Wall
authors.forename: Gerald
authors.initials: G
authors.lastname: Stubbs
mesh_terms: D000595:Amino Acid Sequence; D001665:Binding Sites; D002213:Capsid / Q000737:chemistry* / Q000648:ultrastructure*; D036022:Capsid Proteins / Q000737:chemistry*; D020285:Cryoelectron Microscopy; D017348:Microscopy, Electron, Scanning Transmission; D017863:Potexvirus / Q000737:chemistry / Q000145:classification / Q000648:ultrastructure*; D017433:Protein Structure, Secondary; D012367:RNA, Viral / Q000737:chemistry; D014961:X-Ray Diffraction
chemical_list: D036022:Capsid Proteins; D012367:RNA, Viral