title: Fatal nosocomial spread of Crimean-Congo hemorrhagic fever with very short incubation period.
abstract: Crimean-Congo hemorrhagic fever is a tick-borne viral zoonosis with the potential of human-to-human transmission with case fatality rates from 3% to 50%. The incubation period depends on host, route of infection, and viral dose. Herein, we report a nosocomial spread of the disease in a hospital at Mashhad, northeastern Iran, with a very short incubation period for one of the secondary cases. The patient was a medical student who had a negligible contact with a Crimean-Congo hemorrhagic fever patient during his admission to the hospital. The time interval between the contact and the onset of symptoms was merely 20 hours. Unfortunately, he died within 1 week of exposure.
authors.affiliation: Department of Infectious Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. naderihr@mums.ac.ir
authors.forename: HamidReza
authors.initials: HR
authors.lastname: Naderi
authors.forename: Fereshte
authors.initials: F
authors.lastname: Sheybani
authors.forename: Amin
authors.initials: A
authors.lastname: Bojdi
authors.forename: Nasrin
authors.initials: N
authors.lastname: Khosravi
authors.forename: Irandokht
authors.initials: I
authors.lastname: Mostafavi
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D003428:Cross Infection; D017809:Fatal Outcome; D005260:Female; D006479:Hemorrhagic Fever, Crimean / Q000635:transmission*; D006801:Humans; D055256:Infectious Disease Incubation Period; D008297:Male; D016602:Needlestick Injuries; D017713:Platelet Transfusion; D011239:Prednisolone / Q000627:therapeutic use; D012254:Ribavirin
chemical_list: D000893:Anti-Inflammatory Agents; D000998:Antiviral Agents; D012254:Ribavirin; D011239:Prednisolone