title: Clinical usefulness of Mohs' paste for genital bleeding from the uterine cervix or vaginal stump in gynecologic cancer.
abstract: BACKGROUND
  Atypical genital bleeding due to gynecologic cancer not only impairs patients' quality of life (QOL), but also becomes a major causative factor of death. We report the clinical usefulness of Mohs' paste for genital bleeding from the uterine cervix or vaginal stump in patients with recurrent gynecologic cancer.
  
  
  RESULTS
  Eight patients with gynecologic cancer were enrolled between January 2010 and March 2012. Mohs' paste was directly applied to the bleeding tumor. In patients with recurrent genital bleeding after the application of Mohs' paste, the technique was repeated. The effect of this procedure continued for 4 days to 1 year. The effect of Mohs' paste continued for 3 months or more in three patients. None of the eight patients have died of genital bleeding.
  
  
  CONCLUSIONS
  The use of Mohs' paste is safe and convenient for massive genital bleeding from the uterine cervix or vaginal stump due to recurrent gynecologic cancer. However, our study does have some limitations including the small number of enrolled subjects and heterogeneous cancer types.
authors.affiliation: Department of Obstetrics and Gynecology, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan. s-yana@m3.kufm.kagoshima-u.ac.jp
authors.forename: Yumi
authors.initials: Y
authors.lastname: Yanazume
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Douzono
authors.forename: Shintaro
authors.initials: S
authors.lastname: Yanazume
authors.forename: Kazuto
authors.initials: K
authors.lastname: Iio
authors.forename: Nobuko
authors.initials: N
authors.lastname: Kojima
authors.forename: Keika
authors.initials: K
authors.lastname: Mukaihara
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Douchi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002584:Cervix Uteri / Q000473:pathology*; D002712:Chlorides / Q000627:therapeutic use*; D005260:Female; D005833:Genital Neoplasms, Female / Q000150:complications* / Q000473:pathology*; D005990:Glycerol / Q000627:therapeutic use; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009824:Ointments / Q000627:therapeutic use; D011788:Quality of Life; D016896:Treatment Outcome; D014621:Vagina / Q000473:pathology*; D017967:Zinc Compounds / Q000627:therapeutic use*
chemical_list: D002712:Chlorides; C583017:Mohs' paste; D009824:Ointments; D017967:Zinc Compounds; D005990:Glycerol