title: [The Study of Health in Pomerania (SHIP) reference values for cardiopulmonary exercise testing].
abstract: The interpretation of gas exchange measured by cardiopulmonary exercise testing (CPET) depends on reliable reference values. Within the population based Study of Health in Pomerania (SHIP) CPET was assessed in 1706 volunteers. The assessment based on symptom limited exercise tests on a bicycle in a sitting position according to a modified Jones protocol. CPET was embedded in an extensive examination program. After the exclusion of active smokers and volunteers with evidence of cardiopulmonary and musculoskeletal disorders the reference population comprised 616 healthy subjects (333 women) aged 25 to 85 years. Reference equations including upper and/or lower limits based on quantile regression were assessed. All values were corrected for the most important influencing factors.This study provides reference equations for gas exchange and exercise capacity assessed within a population in Germany.
authors.affiliation: Klinik für Innere Medizin B - Kardiologie, Pneumologie/Infektiologie Intensivmedizin und Weaningzentrum, Universitätsmedizin Greifswald. sven.glaeser@uni-greifswald.de
authors.forename: S
authors.initials: S
authors.lastname: Gläser
authors.forename: T
authors.initials: T
authors.lastname: Ittermann
authors.forename: C
authors.initials: C
authors.lastname: Schäper
authors.forename: A
authors.initials: A
authors.lastname: Obst
authors.forename: M
authors.initials: M
authors.lastname: Dörr
authors.forename: T
authors.initials: T
authors.lastname: Spielhagen
authors.forename: S B
authors.initials: SB
authors.lastname: Felix
authors.forename: H
authors.initials: H
authors.lastname: Völzke
authors.forename: T
authors.initials: T
authors.lastname: Bollmann
authors.forename: C F
authors.initials: CF
authors.lastname: Opitz
authors.forename: C
authors.initials: C
authors.lastname: Warnke
authors.forename: B
authors.initials: B
authors.lastname: Koch
authors.forename: R
authors.initials: R
authors.lastname: Ewert
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005080:Exercise Test / Q000592:standards* / Q000706:statistics & numerical data*; D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011659:Pulmonary Gas Exchange / Q000502:physiology*; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013147:Spirometry / Q000592:standards* / Q000706:statistics & numerical data*