title: An association of craniopharyngioma in Turner syndrome.
abstract: Turner syndrome (TS) (approximately 1:5,000 births) and craniopharyngioma (CP) (1:50,000 children) are both rare conditions. We present three cases of TS with CP, an association not previously described. Visual failure, poor growth or headache led to MRI diagnosis of CP. Whilst two had evidence of hypopituitarism at diagnosis of CP, they all developed hypopituitarism following surgical debulking. Two required radiotherapy due to regrowth. Whether CP and TS share a similar aetiology is unknown. Clinicians need to be aware of this association, and should perform urgent MRI scanning in TS patients with headache, visual impairment or clinical/biochemical evidence of hypopituitarism.
authors.affiliation: Department of Endocrinology and Diabetes, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, United Kingdom.
authors.forename: Aqeel
authors.initials: A
authors.lastname: Farooque
authors.forename: Navoda
authors.initials: N
authors.lastname: Atapattu
authors.forename: Sujeewa
authors.initials: S
authors.lastname: Amarasena
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Högler
authors.forename: Martin W
authors.initials: MW
authors.lastname: English
authors.forename: Jeremy M W
authors.initials: JM
authors.lastname: Kirk
mesh_terms: D000293:Adolescent; D002675:Child, Preschool; D003397:Craniopharyngioma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D010911:Pituitary Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D014424:Turner Syndrome / Q000150:complications*