title: Helicobacter pylori virulence genes detected by string PCR in children from an urban community in northeastern Brazil.
abstract: The accuracy of a nested PCR in gastric DNA obtained by a string test for the diagnosis of Helicobacter pylori infection in asymptomatic children was 94.0%. The cagA-positive toxigenic vacAs1m1 strains were the most prevalent strains, indicating that this population is colonized early by the strains associated with gastric cancer.
authors.affiliation: Clinical Research Unity, Department of Internal Medicine, University Hospital Walter Cantídio, Federal University of Ceará, Fortaleza, Ceará, Brazil.
authors.forename: Maria H R B
authors.initials: MH
authors.lastname: Goncalves
authors.forename: Cícero I S M
authors.initials: CI
authors.lastname: Silva
authors.forename: Manuel B
authors.initials: MB
authors.lastname: Braga-Neto
authors.forename: Andrea B C
authors.initials: AB
authors.lastname: Fialho
authors.forename: Andre M N
authors.initials: AM
authors.lastname: Fialho
authors.forename: Dulciene M M
authors.initials: DM
authors.lastname: Queiroz
authors.forename: Lucia L B C
authors.initials: LL
authors.lastname: Braga
mesh_terms: D000293:Adolescent; D000942:Antigens, Bacterial / Q000235:genetics; D058070:Asymptomatic Diseases; D001426:Bacterial Proteins / Q000235:genetics; D001938:Brazil; D002648:Child; D005260:Female; D005753:Gastric Mucosa / Q000382:microbiology*; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000382:microbiology; D016480:Helicobacter pylori / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity*; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction / Q000379:methods*; D037521:Virulence Factors / Q000235:genetics*
chemical_list: D000942:Antigens, Bacterial; D001426:Bacterial Proteins; C074689:VacA protein, Helicobacter pylori; D037521:Virulence Factors; C080866:cagA protein, Helicobacter pylori