title: [The experience with the application of bacterial lysates in the clinical practice of a pediatrician and otorhinolarynologist].
abstract: The objective of the present study was to analyse the experience with the application of a mixture of bacterial lysates, IRS-19, designed for the treatment of adults and children. The results of an original investigations are presented based on the examination of 60 patients (40 boys and 20 girls) representing a group of frequently ill children. It was shown that the treatment of frequently ill children requires the proper choice of topical lysates for their inclusion in combined therapeutic modalities to control intracellular and mixed infections for the purpose of fast sanitation of the oropharynx and normalization of the throat microflora. The review places special emphasis on the main indications for and approaches to the treatment and prophylaxis of acute, chronic, and recurring diseases affecting the children for the prevention of their complications, such as sinusitis, adenoiditis, and tonsillitis.
authors.forename: M S
authors.initials: MS
authors.lastname: Savenkova
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000293:Adolescent; D000328:Adult; D001419:Bacteria / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification; D002648:Child; D002675:Child, Preschool; D015169:Colony Count, Microbial / Q000379:methods; D057186:Comparative Effectiveness Research; D045424:Complex Mixtures / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D015166:Monitoring, Immunologic; D010614:Pharynx / Q000382:microbiology*; D012141:Respiratory Tract Infections / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology; D055502:Secondary Prevention; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000276:Adjuvants, Immunologic; D045424:Complex Mixtures; C079233:IRS 19