title: [A case of sigmoid colon cancer with Virchow's lymph node metastasis successfully treated with chemotherapy].
abstract: We report the case of a 71-year-old woman suffering from advanced sigmoid colon cancer with Virchow's and para- aortic lymph node metastasis. Sigmoidectomy was performed for sigmoid colon cancer in January 2008, and pathological analysis revealed that it was Stage II(pT3, pN0, pM0, Cur A). The patient received capecitabine regimen as adjuvant chemotherapy from February 2008 to July 2008. However, in August 2008, a left cervical mass was detected associated with swelling, which was partially resected. Microscopic findings revealed lymph node metastasis from sigmoid colon cancer, and Virchow's and para-aortic lymph node metastasis were diagnosed. Therapy with FOLFOX and bevacizumab (Bmab) was started and continued for 8 cycles. Virchow's and para-aortic lymph node metastasis could no longer be detected in June 2009. FOLFOX+Bmab treatment was administered for 33 cycles and oxaliplatin was temporarily stopped due to adverse reactions, including neutropenia, peripheral neuropathy, and appetite loss. She had no recurrence for almost 3 years after stopping chemotherapy for Virchow's and para-aortic lymph node metastasis.
authors.affiliation: Dept. of Surgery, Osaka Rosai Hospital, Osaka, Japan.
authors.forename: Ho
authors.initials: H
authors.lastname: Min Kim
authors.forename: Junichi
authors.initials: J
authors.lastname: Hasegawa
authors.forename: Masaki
authors.initials: M
authors.lastname: Hirota
authors.forename: Nobuki
authors.initials: N
authors.lastname: Matsunami
authors.forename: Shoki
authors.initials: S
authors.lastname: Mikata
authors.forename: Junzo
authors.initials: J
authors.lastname: Shimizu
authors.forename: Yong Kong
authors.initials: YK
authors.lastname: Kim
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Morishima
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Soma
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Miyake
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Matsuura
authors.forename: Tomoyo
authors.initials: T
authors.lastname: Kubota
authors.forename: Harunobu
authors.initials: H
authors.lastname: Yasuyama
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Yoshikawa
authors.forename: Chikashi
authors.initials: C
authors.lastname: Watase
authors.forename: Hideaki
authors.initials: H
authors.lastname: Miwa
authors.forename: Riichiro
authors.initials: R
authors.lastname: Nezu
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003082:Colectomy; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D012811:Sigmoid Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery