title: Enantioselective synthesis of planar chiral ferrocenes via palladium-catalyzed direct coupling with arylboronic acids.
abstract: Enantioselective Pd(II)-catalyzed direct coupling of aminomethylferrocene derivatives with boronic acids was realized. With commercially available Boc-L-Val-OH as a ligand, planar-chiral ferrocenes could be synthesized in yields of 14-81% with up to 99% ee under mild conditions.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, PR China.
authors.forename: De-Wei
authors.initials: DW
authors.lastname: Gao
authors.forename: Yan-Chao
authors.initials: YC
authors.lastname: Shi
authors.forename: Qing
authors.initials: Q
authors.lastname: Gu
authors.forename: Zheng-Le
authors.initials: ZL
authors.lastname: Zhao
authors.forename: Shu-Li
authors.initials: SL
authors.lastname: You
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D005296:Ferrous Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D000075163:Metallocenes; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001897:Boronic Acids; D005296:Ferrous Compounds; D000075163:Metallocenes; D009942:Organometallic Compounds; D010165:Palladium; C004998:ferrocene