title: The renal arterial resistive index and stage of chronic kidney disease in patients with renal allograft.
abstract: OBJECTIVE
  The study investigated the optimal threshold value of renal arterial resistive index as assessed by Doppler ultrasonography determining chronic kidney disease stage 4 or higher in patients with renal allograft.
  
  
  METHODS
  In a cross-sectional study the renal arterial resistive index were obtained in interlobar arteries by Doppler ultrasonography in 78 patients with renal allograft. The stage of chronic kidney disease was determined by the estimated glomerular filtration rate equation.
  
  
  RESULTS
  The median renal arterial resistive index was 0.61 (interquartile range, 0.56 to 0.66). We observed a significant association between renal arterial resistive index above the upper quartile and chronic kidney disease stage 4 or higher (relative risk, 4.64; 95% confidence interval, 1.71 to 12.55; p = 0.003 by Fisher's exact test). Multivariate logistic regression analysis showed that renal arterial resistive indices (p = 0.02) and time since transplantation (p = 0.04), but not age, gender, or blood pressure were significantly associated with chronic kidney disease stage 4 or higher.
  
  
  CONCLUSIONS
  A renal arterial resistive index higher than 0.66 may determine the threshold value of chronic kidney disease stage 4 or higher in patients with renal allograft.
authors.affiliation: Department of Nephrology, Odense University Hospital, Odense, Denmark.
authors.forename: Stine O
authors.initials: SO
authors.lastname: Winther
authors.forename: Helle C
authors.initials: HC
authors.lastname: Thiesson
authors.forename: Lene N
authors.initials: LN
authors.lastname: Poulsen
authors.forename: Mahtab
authors.initials: M
authors.lastname: Chehri
authors.forename: Hanne
authors.initials: H
authors.lastname: Agerskov
authors.forename: Martin
authors.initials: M
authors.lastname: Tepel
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D053208:Kaplan-Meier Estimate; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000503:physiopathology*; D051436:Renal Insufficiency, Chronic / Q000000981:diagnostic imaging / Q000209:etiology* / Q000378:metabolism / Q000503:physiopathology*; D014184:Transplantation, Homologous; D018608:Ultrasonography, Doppler; D014655:Vascular Resistance