title: A dancer caught midstep: the structure of ATP-bound Hsp70.
abstract: Hsp70 ATP binding induces substrate release, but the transiency of this state has inhibited its characterization. In this issue, Kityk et al. determine the Hsp70(∗)ATP structure utilizing engineered disulfide bonds, providing insights into the workings of this essential molecular machine.
authors.affiliation: Department of Biochemistry, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA. sousa@uthscsa.edu
authors.forename: Rui
authors.initials: R
authors.lastname: Sousa