title: Analysis of Taiwan patents for the medicinal mushroom "Niu-Chang- Chih".
abstract: "Niu-Chang-Chih" (Antrodia cinnanomea) is a medicinal mushroom that has only been collected from the aromatic tree, Cinnamomum kanehirai, which is native to Taiwan. A total of 105 Taiwan patent applications and patents for "Niu-Chang-Chih" were collected and analyzed. Patent applications and granted patents claiming newly identified functional components from "Niu-Chang-Chih," biologically pure cultures of the mushroom strain, and cultivation of "Niu-Chang-Chih" were examined. Several applications and patents claim identified active compounds from "Niu-Chang- Chih," which provide better patent protection. These newly identified functional compounds include cyclohexanones, maleic and succinic acid derivatives, labdane diterpenoids, and benzenoids. Newly identified functional proteins include a glutathione-dependent formaldehyde dehydrogenase (GFD), a glycoprotein named ACA1, and a laccase. Newly identified functional polysaccharides include ACP1, ACP2, and ACP3. The number of patents for newly identified compounds and their uses are expected to continue growing.
authors.affiliation: Bioresource Collection and Research Center, Food Industry Research and Development Institute, 331 Shih-Pin Road, Hsinchu 300, Taiwan. yfc@firdi.org.tw
authors.forename: Yu-Fen
authors.initials: YF
authors.lastname: Chen
authors.forename: Wen-Ling
authors.initials: WL
authors.lastname: Lu
authors.forename: Ming-Der
authors.initials: MD
authors.lastname: Wu
authors.forename: Gwo-Fang
authors.initials: GF
authors.lastname: Yuan
mesh_terms: D000363:Agaricales; D055491:Antrodia / Q000737:chemistry*; D001688:Biological Products / Q000737:chemistry*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D006801:Humans; D010330:Patents as Topic; D011134:Polysaccharides / Q000032:analysis; D011506:Proteins / Q000032:analysis; D013624:Taiwan
chemical_list: D001688:Biological Products; D004365:Drugs, Chinese Herbal; D011134:Polysaccharides; D011506:Proteins