title: Serial measurement of high-sensitivity cardiac troponin I and N-terminal proB-type natriuretic peptide in a patient presenting with cardiac sarcoidosis.
abstract: A 65-year-old woman presenting with cardiac sarcoidosis underwent serial measurement of her serum high-sensitivity cardiac troponin I (Hs-cTnI) and N-terminal proB-type natriuretic peptide (NT-proBNP) concentrations. She was treated with 1,000 mg/day methylprednisolone for 2 days, which was subsequently replaced by 30 mg/day prednisolone, and decreased to 20 mg/day at the time of discharge, 2 months later. Her echocardiogram showed improvements in the left ventricular systolic and diastolic function, along with a decrease in the concentration of Hs-cTnI and NT-proBNP. This is the first report suggesting that Hs-cTnI might be a reliable means of assessing the effects of treatment of cardiac sarcoidosis.
authors.affiliation: Department of Cardiology, Hyogo Prefectural Amagasaki Hospital, Japan. ytanada@kuhp.kyotp-u.ac.jp
authors.forename: Yohei
authors.initials: Y
authors.lastname: Tanada
authors.forename: Yukihito
authors.initials: Y
authors.lastname: Sato
authors.forename: Takuma
authors.initials: T
authors.lastname: Sawa
authors.forename: Hisayoshi
authors.initials: H
authors.lastname: Fujiwara
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Takatsu
mesh_terms: D000368:Aged; D009202:Cardiomyopathies / Q000097:blood*; D005260:Female; D006801:Humans; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D012507:Sarcoidosis / Q000097:blood*; D019210:Troponin I / Q000097:blood*
chemical_list: D010446:Peptide Fragments; D019210:Troponin I; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain