title: Evaluation of the newly proposed simplified histological classification in Japanese cohorts of myeloperoxidase-anti-neutrophil cytoplasmic antibody-associated glomerulonephritis in comparison with other Asian and European cohorts.
abstract: The prognostic value of renal biopsy in anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis is widely recognized; however, there is no consensus regarding its pathological classification. Berden et al. proposed a new classification of glomerulonephritis in ANCA-associated vasculitis (AAV) categorized into focal, crescentic, mixed, and sclerotic classes and showed its prognostic value in 100 international multicenter cohorts for 1- and 5-year renal outcomes. In order to evaluate whether this new classification has predictive value and reproducibility in Japanese AAV cases, 87 cohorts with only microscopic polyangiitis in 3 limited centers in Japan were analyzed. In addition, those from Japan, Europe (Berden's cohorts) and China were compared in a recent report.
authors.affiliation: Division of Nephrology and Dialysis, Kitano Hospital, The Tazuke Kofukai Medical Research Institute, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan. muso@kitano-hp.or.jp.
authors.forename: Eri
authors.initials: E
authors.lastname: Muso
authors.affiliation: Division of Nephrology and Dialysis, Kitano Hospital, The Tazuke Kofukai Medical Research Institute, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.
authors.forename: Tomomi
authors.initials: T
authors.lastname: Endo
authors.affiliation: 4th Department of Internal Medicine, Tokyo Women Medical College, Tokyo, Japan.
authors.forename: Mitsuyo
authors.initials: M
authors.lastname: Itabashi
authors.affiliation: Division of Nephrology and Dialysis, Kitano Hospital, The Tazuke Kofukai Medical Research Institute, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Kakita
authors.affiliation: Division of Nephrology and Dialysis, Kitano Hospital, The Tazuke Kofukai Medical Research Institute, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.
authors.forename: Yukako
authors.initials: Y
authors.lastname: Iwasaki
authors.affiliation: Division of Nephrology and Dialysis, Kitano Hospital, The Tazuke Kofukai Medical Research Institute, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.
authors.forename: Yu
authors.initials: Y
authors.lastname: Tateishi
authors.affiliation: Division of Nephrology and Dialysis, Kitano Hospital, The Tazuke Kofukai Medical Research Institute, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Komiya
authors.affiliation: Division of Nephrology and Dialysis, Kitano Hospital, The Tazuke Kofukai Medical Research Institute, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan.
authors.forename: Toshiko
authors.initials: T
authors.lastname: Ihara
authors.affiliation: Preventive Medical Center, Department of Nephrology, International University of Health and Welfare Hospital, Tochigi, Japan.
authors.forename: Wako
authors.initials: W
authors.lastname: Yumura
authors.affiliation: Division of Internal Medicine, Shimoshizu National Hospital, Chiba, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Sugiyama
authors.affiliation: Division of Pathology, Sendai Shakaihoken Hospital, Miyagi, Japan.
authors.forename: Kensuke
authors.initials: K
authors.lastname: Joh
authors.affiliation: Safety Control Department, University Hospital, School of Medicine/General, Medical Education Center, Teikyo University, Tokyo, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Suzuki
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D056648:Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis / Q000145:classification / Q000453:epidemiology / Q000276:immunology / Q000473:pathology*; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D002681:China / Q000453:epidemiology; D018450:Disease Progression; D005060:Europe / Q000453:epidemiology; D005260:Female; D005921:Glomerulonephritis / Q000145:classification / Q000453:epidemiology / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007564:Japan / Q000453:epidemiology; D007676:Kidney Failure, Chronic / Q000453:epidemiology / Q000276:immunology / Q000473:pathology; D007678:Kidney Glomerulus / Q000276:immunology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009195:Peroxidase / Q000276:immunology*; D011237:Predictive Value of Tests; D011379:Prognosis; D009626:Terminology as Topic; D013997:Time Factors; D055815:Young Adult
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D015415:Biomarkers; D009195:Peroxidase