title: New circulating genomic variant of Crimean-Congo hemorrhagic fever virus in Iran.
abstract: Crimean-Congo hemorrhagic fever is a viral infection that is caused by Crimean-Congo hemorrhagic fever virus (CCHFV). On May 27, 2012, a woman became ill after accidentally splashing cow's blood into her eyes. Serological and molecular investigations were carried out on the serum of the patient. The test results for serological testing were negative, but RT-PCR was strongly positive for CCHFV. A phylogenetic study on the CCHFV genome sequence showed 50 % similarity to a 520-bp region of Russian strains. By combining historical phylogenetic data and current data, it can be surmised that there are potentially more than five circulating CCHFV genomic variants in Iran.
authors.affiliation: Arboviruses and Viral Haemorrhagic Fevers Laboratory National Ref. Lab, Pasteur Institute of Iran, Tehran, Iran. sadeghchinikar@yahoo.com
authors.forename: Sadegh
authors.initials: S
authors.lastname: Chinikar
authors.forename: Nariman
authors.initials: N
authors.lastname: Shah-Hosseini
authors.forename: Saeid
authors.initials: S
authors.lastname: Bouzari
authors.forename: Tahmineh
authors.initials: T
authors.lastname: Jalali
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Shokrgozar
authors.forename: Ehsan
authors.initials: E
authors.lastname: Mostafavi
mesh_terms: D005260:Female; D003225:Hemorrhagic Fever Virus, Crimean-Congo / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D006479:Hemorrhagic Fever, Crimean / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008875:Middle Aged; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid
chemical_list: D012367:RNA, Viral