title: Synthesis of the putative structure of (±)-amarbellisine.
abstract: The title compound was synthesized mainly by palladium catalytic coupling, cyclopropyl ring-opening rearrangement, epoxidation, Swern oxidation, demethanol reactions, and selective reduction. This synthesis was achieved in 16 steps with 9.7% overall yield. Unfortunately, the published spectroscopic data do not match with those of our synthetic compound.
authors.affiliation: Key Laboratory of Medicinal Chemistry for Natural Resource (Yunnan University), Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, Yunnan 650091, PR China.
authors.forename: Dandan
authors.initials: D
authors.lastname: Liu
authors.forename: Jingbo
authors.initials: J
authors.lastname: Chen
authors.forename: Long
authors.initials: L
authors.lastname: Ai
authors.forename: Hongbin
authors.initials: H
authors.lastname: Zhang
authors.forename: Jianping
authors.initials: J
authors.lastname: Liu
mesh_terms: D047151:Amaryllidaceae Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry; D010617:Phenanthridines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D047151:Amaryllidaceae Alkaloids; D010617:Phenanthridines; C580729:amarbellisine; D010165:Palladium