title: Resetting for the next generation.
abstract: In this issue of Molecular Cell, Seisenberger et al. (2012) refine DNA methylation mapping to interrogate the epigenetic reprogramming of primordial germ cells, defining the timings of methylation loss, linking to pluripotency, and identifying potential routes to transgenerational epigenetic inheritance.
authors.affiliation: Department of Medical and Molecular Genetics, King's College London, Eighth Floor Tower Wing, Guy's Hospital, London SE1 9RT, UK.
authors.forename: Michael
authors.initials: M
authors.lastname: Cowley
authors.forename: Rebecca J
authors.initials: RJ
authors.lastname: Oakey