title: [Onset of a fulminant malignant hyperthermia crisis. Case report of a 74-year-old patient with previously subclinical central core disease].
abstract: Malignant hyperthermia (MH) is a latent, autosomal dominant inherited syndrome of skeletal musculature which  results in excessive hypermetabolism induced by halogenated anesthetic agents and depolarizing muscle relaxants and is caused by an uncontrolled intramuscular calcium release. This case report focuses on the description of symptoms of a fulminant MH crisis. A possible link between central core disease (CCD) and the clinical severity of MH crisis is postulated in this paper.
authors.affiliation: Klinische Abteilung für Neuro- und Gesichtschirurgische Anästhesiologie und Intensivmedizin, Medizinische Universität Graz, Auenbruggerplatz 29, 8036 Graz, Österreich. mischa.wejbora@medunigraz.at
authors.forename: M
authors.initials: M
authors.lastname: Wejbora
authors.forename: H
authors.initials: H
authors.lastname: Bornemann-Cimenti
authors.forename: D
authors.initials: D
authors.lastname: Lessel
authors.forename: C
authors.initials: C
authors.lastname: Mandl
authors.forename: H
authors.initials: H
authors.lastname: Voit-Augustin
authors.forename: G
authors.initials: G
authors.lastname: Schwarz
mesh_terms: D000328:Adult; D000758:Anesthesia; D020022:Genetic Predisposition to Disease; D006801:Humans; D007431:Intraoperative Complications / Q000628:therapy; D008297:Male; D008305:Malignant Hyperthermia / Q000175:diagnosis / Q000235:genetics / Q000628:therapy*; D020512:Myopathy, Central Core / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D010375:Pedigree