title: Supramolecular coordination and antimicrobial activities of constructed mixed ligand complexes.
abstract: A novel series of copper(II) and palladium(II) with 4-derivatives benzaldehyde pyrazolone (L(n)) were synthesized. The mixed ligand complexes were prepared by using 1,10-phenanthroline (Phen) as second ligand. The structure of these complexes was identified and confirm by elemental analysis, molar conductivity, UV-Vis, IR and (1)H NMR spectroscopy and magnetic moment measurements as well as thermal analysis. The ligand behaves as a neutral bidentate ligand through ON donor sites. ESR spectra show the simultaneous presence of a planar trans and a nearly planar cis isomers in the 1:2 ratio for all N,O complexes [Cu(L(n))(2)]Cl(2)⋅2H(2)O. Schiff bases (L(n)) were tested against bacterial species; namely two Gram positive bacteria (Staphylococcus aureus and Bacillus cereus) and two Gram negative bacteria (Escherichia coli and Klebsiella pneumoniae) and fungal species (Aspergillus niger, Fusarium oxysporium, Penicillium italicum and Alternaria alternata). The tested compounds have antibacterial activity against S. aureus, B. cereus and K. pneumoniae.
authors.affiliation: Chemistry Department, Faculty of Science, Damietta University, Damietta, Egypt. elsonbatisch@yahoo.com
authors.forename: A Z
authors.initials: AZ
authors.lastname: El-Sonbati
authors.forename: M A
authors.initials: MA
authors.lastname: Diab
authors.forename: A A
authors.initials: AA
authors.lastname: El-Bindary
authors.forename: M I
authors.initials: MI
authors.lastname: Abou-Dobara
authors.forename: H A
authors.initials: HA
authors.lastname: Seyam
mesh_terms: D000675:Ampyrone / Q000737:chemistry / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D056831:Coordination Complexes / Q000737:chemistry / Q000494:pharmacology; D003300:Copper / Q000737:chemistry / Q000494:pharmacology; D004578:Electron Spin Resonance Spectroscopy; D004583:Electrons; D005658:Fungi / Q000187:drug effects; D008024:Ligands; D060328:Magnetic Phenomena; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010165:Palladium / Q000737:chemistry; D012545:Schiff Bases / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013818:Thermogravimetry; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D056831:Coordination Complexes; D008024:Ligands; D012545:Schiff Bases; D000675:Ampyrone; D010165:Palladium; D003300:Copper