title: Bioaccessibility of enniatins A, A₁, B, and B₁ in different commercial breakfast cereals, cookies, and breads of Spain.
abstract: Fusarotoxins enniatins (ENs) can represent a potential risk as natural contaminants of cereal commodities. However, only their bioaccessible fraction can exert a toxicity. The purpose of this study was to determine the ENs A, A₁, B, and B₁ bioaccessibility added in 1.5 and 3.0 μmol/g concentrations in breakfast cereals, cookies, and breads using a simulated in vitro gastrointestinal extraction model. Bioaccessibility values ranged between 40.4 ± 1.9 and 79.9 ± 2.8%. The lower values were 50.1, 40.4, 43.9, and 46.3% in wheat bran with fibers, and the higher values were 79.9, 64.2, 69.8, and 73.6% in white loaf bread for the ENs A, A₁, B, and B₁, respectively. Food composition, compounds structure, and presence of natural adsorbing materials can influence the ENs bioaccessibility. Application of a simulated in vitro gastrointestinal method is a good procedure to assess oral ENs bioaccessibility in cookies, breakfast cereals, and bread.
authors.affiliation: Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av. Vicent Andres Estelles s/n, 46100 Burjassot, Valencia, Spain. alessandra.prosperini@uv.es
authors.forename: Alessandra
authors.initials: A
authors.lastname: Prosperini
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Meca
authors.forename: Guillermina
authors.initials: G
authors.lastname: Font
authors.forename: María-José
authors.initials: MJ
authors.lastname: Ruiz
mesh_terms: D001939:Bread / Q000032:analysis*; D047630:Depsipeptides / Q000032:analysis / Q000378:metabolism*; D004032:Diet / Q000208:ethnology; D004043:Dietary Fiber / Q000032:analysis* / Q000378:metabolism; D004063:Digestion; D002523:Edible Grain / Q000737:chemistry* / Q000378:metabolism; D057140:Fast Foods / Q000032:analysis*; D005506:Food Contamination; D006801:Humans; D007408:Intestinal Absorption; D009183:Mycotoxins / Q000032:analysis / Q000378:metabolism*; D013030:Spain
chemical_list: D047630:Depsipeptides; D004043:Dietary Fiber; D009183:Mycotoxins; C100264:enniatins