title: Laparoscopic adrenalectomy for large tumours: Single team experience.
abstract: BACKGROUND
  Laparoscopic adrenalectomy (LA) has become the procedure of choice to treat benign functioning and non-functioning adrenal tumours. With improving experience, large adrenal tumours (> 5 cm) are being successfully tackled by laparoscopy. This study aims to present our single unit experience of LA performed for large adrenal masses.
  
  
  METHODS
  Forty-six laparoscopic adrenalectomies performed for large adrenal lesions more than 5 cm during the period 2001 to 2010 were reviewed.
  
  
  RESULTS
  A total of 46 adrenalectomies were done in 42 patients. The mean tumour size was 7.03 cm (5-15 cm). Fourteen patients had tumour size more than 8 cm. The lesions were localised on the right side in 17 patients and on the left side in 21 patients with bilateral tumours in 4 patients. Functioning tumours were present in 32 of the 46 patients. The average blood loss was 112 ml (range 20-400 ml) with the mean operating time being 144 min (range 45 to 270 min). Five patients required conversion to open procedure. Three of the 46 patients (6.52%) on final histology had malignant tumours.
  
  
  CONCLUSIONS
  LA is safe and feasible for large adrenal lesions. Mere size should not be considered as a contraindication to laparoscopic approach in large adrenal masses. Graded approach, good preoperative assessment, team work and adherence to anatomical and surgical principles are the key to success.
authors.affiliation: Department of General Surgery, Seth G. S. Medical College and King Edward VII Memorial Hospital, Mumbai, Maharashtra, India.
authors.forename: Abhay N
authors.initials: AN
authors.lastname: Dalvi
authors.forename: Pinky M
authors.initials: PM
authors.lastname: Thapar
authors.forename: Vinaykumar B
authors.initials: VB
authors.lastname: Thapar
authors.forename: Sameer A
authors.initials: SA
authors.lastname: Rege
authors.forename: Aparna A
authors.initials: AA
authors.lastname: Deshpande