title: [The differential approach to the treatment of exudative otitis media with the use of mucosal immunocorrection].
abstract: The objective of the present study was to improve the efficacy of the treatment of the patients suffering from exudtaive otitis media (EOM). A total of 75 patients presenting with EOM were allocated to 2 groups. In one of them (n=36) the patients were treated using conventional therapeutic modalities, in the other one (n=39) with the use of a local immunomodulator (a 0.04% synthetic tetradecapeptide solution). The local application of the immunocorrective agent has demonstrated its normalizing action on the parameters of both local and systemic immunity. It is concluded that the adequate and timely treatment with the use of synthetic tetradecapeptide reduces the probability of relapse and chronization of the pathological process which not infrequently allows the surgical intervention to be avoided.
authors.forename: D D
authors.initials: DD
authors.lastname: Ochirov
authors.forename: N V
authors.initials: NV
authors.lastname: Shcherbik
authors.forename: E N
authors.initials: EN
authors.lastname: Kologrivova
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000287:Administration, Topical; D000328:Adult; D001826:Body Fluids / Q000276:immunology; D004432:Ear, Middle / Q000187:drug effects* / Q000276:immunology; D005260:Female; D006314:Hearing Loss, Conductive / Q000175:diagnosis; D006320:Hearing Tests; D006801:Humans; D056747:Immunomodulation; D008297:Male; D015166:Monitoring, Immunologic / Q000379:methods; D009842:Oligopeptides / Q000008:administration & dosage; D010034:Otitis Media with Effusion / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology / Q000503:physiopathology; D011379:Prognosis; D011677:Punctures / Q000379:methods*; D016896:Treatment Outcome; D014432:Tympanic Membrane
chemical_list: D000276:Adjuvants, Immunologic; D009842:Oligopeptides; C523770:Thr-Glu-Lys-Lys-Arg-Arg-Glu-Thr-Val-Glu-Arg-Glu-Lys-Glu