title: Salivary lysozyme in smoking alcohol dependent persons.
abstract: The purpose of this study was to evaluate the effect of chronic alcohol intoxication and smoking on the concentration and output of salivary lysozyme. Thirty seven men participated in the study, including 17 male smoking alcohol-dependent patients after chronic alcohol intoxication (AS), and 20 control non-smoking male social drinkers (CNS) with no history of alcohol abuse or smoking. The level of lysozyme was assessed by the radial immunodiffusion method. Significantly lower lysozyme output in the AS group compared to the CNS group was found. Moreover, gingival index was significantly higher in AS than in the CNS group. It appeared that the reduced salivary lysozyme output was more likely the result of ethanol action than smoking. In conclusion, persons addicted to alcohol and nicotine have a poorer periodontal status than non-smoking social drinkers, which may partially be due to the diminished protective effects of lysozyme present in the saliva.
authors.affiliation: Department of Psychiatry, Medical University of Białystok, Poland. napoleonwas@yahoo.com
authors.forename: Napoleon
authors.initials: N
authors.lastname: Waszkiewicz
authors.forename: Beata
authors.initials: B
authors.lastname: Zalewska-Szajda
authors.forename: Anna
authors.initials: A
authors.lastname: Zalewska
authors.forename: Magdalena
authors.initials: M
authors.lastname: Waszkiewicz
authors.forename: Slawomir Dariusz
authors.initials: SD
authors.lastname: Szajda
authors.forename: Bernadeta
authors.initials: B
authors.lastname: Repka
authors.forename: Agata
authors.initials: A
authors.lastname: Szulc
authors.forename: Alina
authors.initials: A
authors.lastname: Kepka
authors.forename: Alina
authors.initials: A
authors.lastname: Minarowska
authors.forename: Jerzy Robert
authors.initials: JR
authors.lastname: Ladny
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Zwierz
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications / Q000201:enzymology*; D016022:Case-Control Studies; D004245:DMF Index; D003771:Dental Papilla / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009113:Muramidase / Q000378:metabolism*; D010512:Periodontal Index; D012463:Saliva / Q000201:enzymology*; D012907:Smoking / Q000378:metabolism*
chemical_list: D009113:Muramidase