title: Multidrug-resistant tuberculosis with a history of nontuberculous Mycobacteriosis: a brief report of two cases.
abstract: We herein report two cases of multidrug-resistant tuberculosis (MDR-TB) in patients with a history of pulmonary nontuberculous mycobacteriosis (PNTM). A 50-year-old man was diagnosed with MDR-TB five years after receiving treatment for pulmonary Mycobacterium kansasii infection. In the second patient, a 72-year-old woman, the diagnosis of PNTM was confirmed twice with two bronchial washings; she was diagnosed with MDR-TB 29 months after presenting with PNTM. It is highly possible that these two patients were already infected with tuberculosis (TB) at the time of PNTM diagnosis and acquired resistance to anti-TB drugs as a result of undergoing treatment for PNTM.
authors.affiliation: Fukujuji Hospital, Japan Anti-Tuberculosis Association, Japan. bxypb621@ybb.ne.jp
authors.forename: Kozo
authors.initials: K
authors.lastname: Morimoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Yoshiyama
authors.forename: Masao
authors.initials: M
authors.lastname: Okumura
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Hoshino
authors.forename: Kozo
authors.initials: K
authors.lastname: Yoshimori
authors.forename: Hideo
authors.initials: H
authors.lastname: Ogata
authors.forename: Atsuyuki
authors.initials: A
authors.lastname: Kurashima
authors.forename: Akihiko
authors.initials: A
authors.lastname: Gemma
authors.forename: Shoji
authors.initials: S
authors.lastname: Kudoh
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications*; D018088:Tuberculosis, Multidrug-Resistant / Q000150:complications*; D014397:Tuberculosis, Pulmonary / Q000150:complications*