title: Patented biotechnological applications of serpin: an update.
abstract: The Serine Protease Inhibitors (Serpins) have been a focus of research by biomedical industries due to their critical role in human health. The use of serpin in the treatment of many diseases was widely investigated through the identification of new genes encoding these proteins in all kingdoms of life. The characterization of these genes revealed that they encoded proteins having low sequence homologies. Future developments are focusing not only on the protease inhibition activity, but also on the other effects due to the interactions of serpins with other components such as hormone transport. Here we give a concise overview of the most recent patents that have been reported in this field of research.
authors.affiliation: INRA, UMR1319 Micalis Domaine de Vilvert, F-78350 Jouy-en-Josas.
authors.forename: Nadia
authors.initials: N
authors.lastname: Gaci
authors.forename: Dragana
authors.initials: D
authors.lastname: Dobrijevic
authors.forename: Samira
authors.initials: S
authors.lastname: Boudebbouze
authors.forename: Bouziane
authors.initials: B
authors.lastname: Moumen
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Maguin
authors.forename: Moez
authors.initials: M
authors.lastname: Rhimi
mesh_terms: D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000627:therapeutic use; D000925:Anticoagulants / Q000737:chemistry / Q000627:therapeutic use; D000998:Antiviral Agents / Q000737:chemistry / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000188:drug therapy; D005342:Fibrinolysis; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy; D009369:Neoplasms / Q000175:diagnosis; D010330:Patents as Topic; D015843:Serpins / Q000737:chemistry / Q000627:therapeutic use*; D014777:Virus Diseases / Q000188:drug therapy
chemical_list: D000893:Anti-Inflammatory Agents; D000925:Anticoagulants; D000998:Antiviral Agents; D015843:Serpins