title: Comparison of myocardial perfusion imaging between the new high-speed gamma camera and the standard anger camera.
abstract: BACKGROUND
  Cadmium-zinc-telluride (CZT) solid-state detectors have been recently introduced into the field of myocardial perfusion imaging. The aim of this study was to prospectively compare the diagnostic performance of the CZT high-speed gamma camera (Discovery NM 530c) with that of the standard 3-head gamma camera in the same group of patients.
  
  
  RESULTS
  The study group consisted of 150 consecutive patients who underwent a 1-day stress-rest (99m)Tc-sestamibi or tetrofosmin imaging protocol. Image acquisition was performed first on a standard gamma camera with a 15-min scan time each for stress and for rest. All scans were immediately repeated on a CZT camera with a 5-min scan time for stress and a 3-min scan time for rest, using list mode. The correlations between the CZT camera and the standard camera for perfusion and function analyses were strong within narrow Bland-Altman limits of agreement. Using list mode analysis, image quality for stress was rated as good or excellent in 97% of the 3-min scans, and in 100% of the ≥4-min scans. For CZT scans at rest, similarly, image quality was rated as good or excellent in 94% of the 1-min scans, and in 100% of the ≥2-min scans.
  
  
  CONCLUSIONS
  The novel CZT camera provides excellent image quality, which is equivalent to standard myocardial single-photon emission computed tomography, despite a short scan time of less than half of the standard time.
authors.affiliation: Department of Cardiology, Tokyo Medical University, Tokyo, Japan. htanaka7@tokyo-med.ac.jp
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Tanaka
authors.forename: Taishiro
authors.initials: T
authors.lastname: Chikamori
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hida
authors.forename: Kenji
authors.initials: K
authors.lastname: Uchida
authors.forename: Yuko
authors.initials: Y
authors.lastname: Igarashi
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Yokoyama
authors.forename: Masaki
authors.initials: M
authors.lastname: Takahashi
authors.forename: Chie
authors.initials: C
authors.lastname: Shiba
authors.forename: Mana
authors.initials: M
authors.lastname: Yoshimura
authors.forename: Koichi
authors.initials: K
authors.lastname: Tokuuye
authors.forename: Akira
authors.initials: A
authors.lastname: Yamashina
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055414:Myocardial Perfusion Imaging / Q000295:instrumentation / Q000379:methods; D009943:Organophosphorus Compounds / Q000008:administration & dosage*; D015609:Organotechnetium Compounds / Q000008:administration & dosage*; D049268:Positron-Emission Tomography / Q000295:instrumentation / Q000379:methods; D019275:Radiopharmaceuticals / Q000008:administration & dosage*; D017256:Technetium Tc 99m Sestamibi / Q000008:administration & dosage*
chemical_list: D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin; D017256:Technetium Tc 99m Sestamibi