title: Recalcitrant cutaneous ulcer of comorbid patient treated with platelet rich plasma: a case report.
abstract: The platelet-rich plasma (PRP) has been advocated as a way to introduce increased concentrations of growth factors and other bioactive molecules to injured tissues in an attempt to optimize the local healing environment. A 94-yr-old woman with various comorbidities presented with a two-week history of severe cutaneous ulcer on the left dorsum of foot. It was caused by recurrent mechanical trauma and did not respond to several wound debridement and simple dressings. However, after she was completed on seven times of autologous PRP treatments, we observed complete healing of the skin lesion within 3 months. Herein, we report a case of recalcitrant cutaneous ulcer with various comorbidities and discuss about the promising possibility of autologous PRP as an effective alternative therapeutic modality.
authors.affiliation: Department of Dermatology, Korea University College of Medicine, Seoul, Korea.
authors.forename: Dai Hyun
authors.initials: DH
authors.lastname: Kim
authors.forename: Jong Yeob
authors.initials: JY
authors.lastname: Kim
authors.forename: Soo Hong
authors.initials: SH
authors.lastname: Seo
authors.forename: Hyo Hyun
authors.initials: HH
authors.lastname: Ahn
authors.forename: Young Chul
authors.initials: YC
authors.lastname: Kye
authors.forename: Jae Eun
authors.initials: JE
authors.lastname: Choi
mesh_terms: D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D053657:Platelet-Rich Plasma; D012883:Skin Ulcer / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome; D014945:Wound Healing