title: Clinical observations on attention-deficit hyperactivity disorder (ADHD) in children with frontal lobe epilepsy.
abstract: The objective was to investigate the prevalence of attention-deficit hyperactivity disorder (ADHD) in children with frontal lobe epilepsy and related factors. The medical records of 190 children diagnosed with frontal lobe epilepsy at Qilu Hospital of Shandong University between 2006 and 2011 were retrospectively collected, and a follow-up analysis of the prevalence of ADHD in these children was conducted. Of the 161 children with an effective follow-up, 59.0% (95/161) with frontal lobe epilepsy suffered from ADHD as well. Analysis of epilepsy and ADHD-related factors indicated that the incidence of ADHD was 89.4% (76/85) in children with abnormal electroencephalogram (EEG) discharges on the most recent EEG, which was significantly higher than the ADHD incidence of 25% (19/76) in children with normal readings on the most recent EEG (P < .01). Children with frontal lobe epilepsy have a high incidence of ADHD. Sustained abnormal discharge on the electroencephalogram is associated with increased comorbidity of ADHD with frontal lobe epilepsy.
authors.affiliation: 1Department of Pediatrics, Qilu Hospital, Shandong University, Jinan, China.
authors.forename: Dong-Qing
authors.initials: DQ
authors.lastname: Zhang
authors.forename: Fu-Hai
authors.initials: FH
authors.lastname: Li
authors.forename: Xiao-Bo
authors.initials: XB
authors.lastname: Zhu
authors.forename: Ruo-Peng
authors.initials: RP
authors.lastname: Sun
mesh_terms: D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications* / Q000453:epidemiology*; D016009:Chi-Square Distribution; D002648:Child; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications / Q000453:epidemiology / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans; D008297:Male; D019370:Observation; D015995:Prevalence; D012189:Retrospective Studies