title: Therapy with climara in surgical menopause.
abstract: Hormone replacement therapy in surgical menopause is a prophylactic measure that is used for preventing the short and long term effects of the lack of ovarian hormones.
  
  
  METHODS
  This is a retrospective study conducted between 2004 and 2006 at the Iasi "Elena-Doamna" Hospital of Obstetrics and Gynecology on two series of patients: 46 patients with surgical menopause who received treatment with transdermal estradiol (Climara), and 20 surgical menopause patients not receiving this treatment who served as controls.
  
  
  RESULTS
  A decreases in the average levels of total cholesterol, triglycerides and LDL cholesterol and an increase in the HDL cholesterol level were identified in the series receiving Climara compared to the controls. The climacteric symptoms improved in the patients receiving treatment.
  
  
  CONCLUSIONS
  Transdermal therapy with estradiol (Climara) is an effective method of treatment in surgically induced menopause.
authors.affiliation: University of Medicine and Pharmacy Grigore T. Popa-Iasi School of Medicine.
authors.forename: Daniela
authors.initials: D
authors.lastname: Bădoi
authors.forename: E
authors.initials: E
authors.lastname: Crauciuc
authors.forename: Lidia
authors.initials: L
authors.lastname: Rusu
authors.forename: Veronica
authors.initials: V
authors.lastname: Luca
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000465:Algorithms; D000704:Analysis of Variance; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D008076:Cholesterol, HDL / Q000097:blood / Q000187:drug effects; D008078:Cholesterol, LDL / Q000097:blood / Q000187:drug effects; D004958:Estradiol / Q000008:administration & dosage*; D015914:Estrogen Replacement Therapy / Q000379:methods; D004967:Estrogens / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects; D008594:Menopause, Premature / Q000097:blood / Q000187:drug effects*; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control; D010052:Ovariectomy / Q000009:adverse effects; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood
chemical_list: D015415:Biomarkers; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004967:Estrogens; D014280:Triglycerides; D004958:Estradiol