title: Impact of sleep as a specific marker of quality of life in allergic rhinitis.
abstract: Allergic rhinitis (AR) is a common disorder, which represents a considerable burden both on individual patients and society. It is associated with bothersome symptoms, which may impair usual daily activities, sleep quality, and productivity. Associated with impaired sleep, quality of life is significantly impaired in AR patients. AR significantly contributes to sleep-disordered breathing through multiple mechanisms, with the greatest impact mediated through nasal obstruction. Sleep impairment is very common in AR patients and has a significant impact on disease-specific measures of general health and quality of life. The degree of sleep disturbance is directly related to the severity of the disease. Nasal congestion also demonstrates circadian rhythm and positional variability, worsening during nighttime hours and in supine position. Increased sleep disordered events lead to poor sleep with fatigue and daytime somnolence, impaired performance, productivity and social functioning, and an increased risk of associated diseases.
authors.affiliation: Department of Allergology, Hospital Quirón. Barcelona, Catalonia, Spain. vgonzaleznu@gmail.com
authors.forename: Vanesa
authors.initials: V
authors.lastname: González-Núñez
authors.forename: Antonio Luís
authors.initials: AL
authors.lastname: Valero
authors.forename: Joaquim
authors.initials: J
authors.lastname: Mullol
mesh_terms: D000203:Activities of Daily Living; D015415:Biomarkers; D006801:Humans; D011788:Quality of Life; D065631:Rhinitis, Allergic; D012221:Rhinitis, Allergic, Perennial / Q000503:physiopathology* / Q000523:psychology; D012890:Sleep / Q000502:physiology*; D012894:Sleep Stages; D012893:Sleep Wake Disorders / Q000503:physiopathology* / Q000523:psychology
chemical_list: D015415:Biomarkers