title: [A case of metastatic liver carcinoma treated with radiofrequency ablation and hepatectomy].
abstract: We report a case of metastatic liver carcinoma treated by radiofrequency ablation (RFA) and hepatectomy. A 53-year-old man suffering from sigmoid colon carcinoma and unresectable multiple liver metastases was treated with capecitabine and oxaliplatin and bevacizumab. After the seventh course, tumor reduction was confirmed but liver dysfunction meant that it was difficult to continue the same regimen. Because preoperative evaluation of liver function showed a high risk of postoperative liver failure, a combination of partial hepatectomy and RFA was planned in order to reduce the amount of liver resection. High anterior resection, partial hepatectomy and RFA were performed as planned. He underwent S-1 therapy following 7 courses of irinotecan, S-1, and bevacizumab therapy. To date, no recurrence has been observed 18 months after the operation. A combination of hepatectomy and RFA is expected to be an effective local treatment for multiple liver metastases of colorectal cancer, although the evidence is currently insufficient.
authors.affiliation: Dept. of Organ Regulatory Surgery, Fukushima Medical University, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Okada
authors.forename: Shun
authors.initials: S
authors.lastname: Chida
authors.forename: Keita
authors.initials: K
authors.lastname: Aoto
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Momma
authors.forename: Rei
authors.initials: R
authors.lastname: Yashima
authors.forename: Satoshi
authors.initials: S
authors.lastname: Suzuki
authors.forename: Izumi
authors.initials: I
authors.lastname: Nakamura
authors.forename: Shinji
authors.initials: S
authors.lastname: Ohki
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Shimura
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Koyama
authors.forename: Seiichi
authors.initials: S
authors.lastname: Takenoshita
mesh_terms: D017115:Catheter Ablation; D003131:Combined Modality Therapy; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012811:Sigmoid Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery