title: Congenital diaphragmatic hernia in neonate: a retrospective study about 28 observations.
abstract: OBJECTIVE
  Our purpose was to review our experience with congenital diaphragmatic hernia emphasizing diagnosis, management, and outcome.
  
  
  METHODS
  We conducted a retrospective review of all cases of babies with congenital diaphragmatic hernia diagnosed and treated in our centre from 1998 to 2010.
  
  
  RESULTS
  There were 28 congenital diaphragmatic hernia cases, 13 girls and 15 boys with a mean weight birth of 3 kg. Three patients (10, 6% of cases) died within a few hours after admission. In the remaining cases, surgery was performed after a stabilization period of 2 days. The diaphragmatic defect was sitting in the posterolateral left in 23 cases and right in 2 cases. Its dimensions were on average 4,5 cm, tow cases of agenesis of the cupola were seen and required the placement of gortex prosthesis. The remaining cases are treated by direct closure of defect. Postoperative course was marked by an early death in context of respiratory distress in six cases and later with sepsis in tow cases. The outcome was favourable in 17 cases (60, 7%), despite the occurrence of sepsis in four cases and evisceration in two cases.
  
  
  CONCLUSIONS
  Congenital diaphragmatic hernia remains a serious disease with high mortality and morbidity despite advances in prenatal diagnosis and neonatal resuscitation.
authors.affiliation: Department of Pediatric Surgery "B", Children's Hospital of Tunis, University of Tunis El Manar, Tunis, Tunisia.
authors.forename: Rachid
authors.initials: R
authors.lastname: Khemakhem
authors.forename: Basma
authors.initials: B
authors.lastname: Haggui
authors.forename: Houda
authors.initials: H
authors.lastname: Rahay
authors.forename: Faouzi
authors.initials: F
authors.lastname: Nouira
authors.forename: Awatef
authors.initials: A
authors.lastname: Charieg
authors.forename: Sofiane
authors.initials: S
authors.lastname: Ghorbel
authors.forename: Mahdi
authors.initials: M
authors.lastname: Trifa
authors.forename: Said
authors.initials: S
authors.lastname: Jlidi
authors.forename: Sonia Ben
authors.initials: SB
authors.lastname: Khalifa
authors.forename: Beji
authors.initials: B
authors.lastname: Chaouachi
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006548:Hernia, Diaphragmatic / Q000175:diagnosis / Q000601:surgery; D065630:Hernias, Diaphragmatic, Congenital; D059685:Herniorrhaphy / Q000379:methods*; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D011296:Prenatal Diagnosis / Q000379:methods*; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors; D014416:Tunisia / Q000453:epidemiology