title: Combined topical application of lotus and green tea improves facial skin surface parameters.
abstract: No study has yet determined the anti-wrinkle efficacy of green tea plus lotus in Asian subjects using skin image analysis technique. In this study, the efficacy of two cosmetic active formulations intended for the treatment of facial wrinkles (green tea and lotus extract) has been evaluated in healthy subjects using a non-invasive device, the Visioscan(®) VC, and software for surface evaluation of living skin (SELS). Thirty-three healthy Asian subjects, all men, were enrolled after consent in a placebo-controlled comparative study with a split face design. One group applied multiple emulsions with green tea. The second group applied multiple emulsions with lotus extract, while a third group applied a multiple emulsion with a combination of both extracts. In all three groups, active formulations were applied to one side of the face and the placebo to the other side, once daily over the 60-day treatment course. Non-invasive measurements were performed at baseline and on days 30 and 60. Interesting and significant improvements were observed for the treatment effects on skin roughness (SEr), scaliness (SEsc), smoothness (SEsm), and wrinkling (SEw). For example, a 49.99% improvement in skin smoothness (SEsm) from baseline value and -23.22% and perfection in facial wrinkles (SEw) substantiated that combined treatment is superior over single treatments. Green tea and lotus combined in multiple emulsions brought a superior synergistic anti-aging effect. We conclude that diverse anti-oxidant constituents in both plants have a potential influence on skin surface parameters, thus indicating these plants as the future of new anti-aging products.
authors.affiliation: Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Pakistan. tariqmahmood750@gmail.com
authors.forename: Tariq
authors.initials: T
authors.lastname: Mahmood
authors.forename: Naveed
authors.initials: N
authors.lastname: Akhtar
mesh_terms: D000287:Administration, Topical; D000328:Adult; D005145:Face; D006801:Humans; D000070116:Lotus / Q000378:metabolism*; D008297:Male; D010936:Plant Extracts / Q000008:administration & dosage* / Q000494:pharmacology*; D015595:Skin Aging / Q000187:drug effects*; D013499:Surface Properties; D013662:Tea / Q000378:metabolism*
chemical_list: D010936:Plant Extracts; D013662:Tea