title: [Formulation of salvia-containing gels].
abstract: The trend during the past years is to prefer natural drugs to synthetically prepared medicines. Due to its important antiphlogistic, antiseptic and antihidrotic effects, Salvia officinalis L. has a wide use in medicine, pharmacy and cosmetics in various dosage forms. The aim of this research was the formulation of Salvia officinalis L. in the form of a tincture to hydrogels. Gels were parallelly prepared on the basis of the natural polymer chitosan and the synthetic polymer Carbopol 940. The evaluation was focused on the influence of the anionic polymer and the cationic polymer in different concentrations on hydrogel flow properties. Glycerol functioning as a humectant was used in various percentage ratios. On the basis of the determination of rheological parameters and flow curves lapses the most suitable hydrogel from the application point of view was selected.
authors.affiliation: Univerzita Komenského v Bratislave, Farmaceutická fakulta, Katedra galenickej farmácie, Odbojárov 10, 832 32 Bratislava, Slovenská republika.
authors.forename: Zuzana
authors.initials: Z
authors.lastname: Vitková
authors.forename: Petra
authors.initials: P
authors.lastname: Herdová
authors.forename: Alexandra
authors.initials: A
authors.lastname: Kodadová
authors.forename: Jana
authors.initials: J
authors.lastname: Seligová
authors.forename: Daniel
authors.initials: D
authors.lastname: Grancai
authors.forename: Dominika
authors.initials: D
authors.lastname: Poláková
mesh_terms: D002626:Chemistry, Pharmaceutical; D006801:Humans; D020100:Hydrogels; D008517:Phytotherapy; D028321:Plant Preparations; D027543:Salvia officinalis
chemical_list: D020100:Hydrogels; D028321:Plant Preparations