title: [A successful case of a super-elderly breast cancer patient treated with hormone therapy].
abstract: A 104-year-old female patient with a left breast mass was admitted to our hospital. Ultrasonography showed an irregular and low-echoic mass of about 2.4×2.4×1.4 cm size in the left breast EAC area. Core needle biopsy examination indicated invasive ductal carcinoma of the breast: ER (+), PR (+), and HER2 (-). An overall examination did not show a distant metastasis. We diagnosed her with left breast cancer(luminal A type) T2N0M0, stage IIA. We administered anastrozole at a dose of 1 mg/day. After 6 months, the primary tumor diameter was reduced to 2.1 cm, and the effect of anastrozole was considered a clinical partial response. The patient did not experience any adverse events during treatment. The partial response was maintained for about 2 years. We experienced a successful case of a super-elderly breast cancer patient treated with anastrozole. We conclude that hormone therapy is a useful treatment for super-elderly postmenopausal women with estrogen receptor-positive breast cancer.
authors.affiliation: Dept. of Surgical Oncology, Osaka City University Graduate School of Medicine, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Aomatsu
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Kashiwagi
authors.forename: Yuka
authors.initials: Y
authors.lastname: Asano
authors.forename: Tamami
authors.initials: T
authors.lastname: Morisaki
authors.forename: Masanori
authors.initials: M
authors.lastname: Nakamura
authors.forename: Hidemi
authors.initials: H
authors.lastname: Kawajiri
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Takashima
authors.forename: Naoyoshi
authors.initials: N
authors.lastname: Onoda
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Kosei
authors.initials: K
authors.lastname: Hirakawa
mesh_terms: D000369:Aged, 80 and over; D000077384:Anastrozole; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D062005:Biopsy, Large-Core Needle; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D009570:Nitriles / Q000627:therapeutic use*; D011788:Quality of Life; D014230:Triazoles / Q000627:therapeutic use*; D014463:Ultrasonography
chemical_list: D018931:Antineoplastic Agents, Hormonal; D009570:Nitriles; D014230:Triazoles; D000077384:Anastrozole