title: [Pain therapy for Fabry's disease].
abstract: Fabry's disease is an X-chromosome linked lysosomal storage disorder with α-galactosidase A deficiency and subsequent multiple organ involvement. An early and common symptom also in later stages of the disease is pain. This pain depends on various precipitating factors and can severely compromise the quality of life. So-called Fabry crises can lead to the necessity for intensive care treatment. The pain can be classified as predominantly neuropathic and is difficult to treat. In addition, medication has to be adjusted to concomitant cardiac and renal involvement in Fabry's disease. This review gives guidance for pain therapy in Fabry's disease based on the available evidence and on experience.
authors.affiliation: Neurologische Klinik, Universitätsklinikum Würzburg, Deutschland. sommer@uni-wuerzburg.de
authors.forename: C
authors.initials: C
authors.lastname: Sommer
authors.forename: N
authors.initials: N
authors.lastname: Uçeyler
authors.forename: T
authors.initials: T
authors.lastname: Duning
authors.forename: K
authors.initials: K
authors.lastname: Arning
authors.forename: R
authors.initials: R
authors.lastname: Baron
authors.forename: E
authors.initials: E
authors.lastname: Brand
authors.forename: S
authors.initials: S
authors.lastname: Canaan-Kühl
authors.forename: M
authors.initials: M
authors.lastname: Hilz
authors.forename: D
authors.initials: D
authors.lastname: Naleschinski
authors.forename: C
authors.initials: C
authors.lastname: Wanner
authors.forename: F
authors.initials: F
authors.lastname: Weidemann
mesh_terms: D000700:Analgesics / Q000627:therapeutic use*; D000795:Fabry Disease / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D009437:Neuralgia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*
chemical_list: D000700:Analgesics