title: Molecular defect of 'Prothrombin Amrita': substitution of arginine by glutamine (Arg553 to Gln) near the Na(+) binding loop of prothrombin.
authors.forename: Sajini
authors.initials: S
authors.lastname: Sivasundar
authors.forename: Akash Thomas
authors.initials: AT
authors.lastname: Oommen
authors.forename: Ohm
authors.initials: O
authors.lastname: Prakash
authors.forename: Sujatha
authors.initials: S
authors.lastname: Baskaran
authors.forename: Raja
authors.initials: R
authors.lastname: Biswas
authors.forename: Shantikumar
authors.initials: S
authors.lastname: Nair
authors.forename: C Gopi
authors.initials: CG
authors.lastname: Mohan
authors.forename: Lalitha
authors.initials: L
authors.lastname: Biswas
mesh_terms: D019943:Amino Acid Substitution; D001120:Arginine; D005973:Glutamine; D006579:Heterozygote; D006801:Humans; D008297:Male; D008875:Middle Aged; D009154:Mutation; D011485:Protein Binding; D011516:Prothrombin / Q000737:chemistry* / Q000235:genetics*; D012964:Sodium / Q000378:metabolism; D020246:Venous Thrombosis / Q000175:diagnosis / Q000235:genetics*
chemical_list: D005973:Glutamine; D011516:Prothrombin; D001120:Arginine; D012964:Sodium