title: Management of fetal hydrops due to maternal antibodies against a low incidence paternal red cell antigen: a novel insight from clinical practice.
abstract: A rare case of a low incidence red cell antigen causing severe fetal allo-immune red cell disease is presented. Discussion of how this can be diagnosed and successfully managed antenatally using middle cerebral artery Doppler ultrasound and maternal antibody titre levels for fetal surveillance and timing of intervention with intrauterine transfusion.
authors.affiliation: Fetal Medicine Unit, Saint Michael's Hospital, United Hospitals Bristol NHS Trust, Bristol, UK. hills.alison@gmail.com
authors.forename: Alison
authors.initials: A
authors.lastname: Hills
authors.forename: Edwin
authors.initials: E
authors.lastname: Massey
authors.forename: Sue
authors.initials: S
authors.lastname: Search
authors.forename: Joyce
authors.initials: J
authors.lastname: Poole
authors.forename: Stephen W
authors.initials: SW
authors.lastname: Jones
authors.forename: John
authors.initials: J
authors.lastname: Moppett
authors.forename: Timothy
authors.initials: T
authors.lastname: Overton
mesh_terms: D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000209:etiology / Q000517:prevention & control*; D000751:Anemia, Neonatal / Q000209:etiology / Q000517:prevention & control*; D001789:Blood Group Antigens / Q000009:adverse effects* / Q000032:analysis; D001805:Blood Transfusion, Intrauterine; D005078:Exchange Transfusion, Whole Blood; D005260:Female; D006801:Humans; D015160:Hydrops Fetalis / Q000000981:diagnostic imaging / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D007231:Infant, Newborn; D008297:Male; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging; D010375:Pedigree; D011247:Pregnancy; D016216:Ultrasonography, Prenatal
chemical_list: D001789:Blood Group Antigens