title: Oral Nicotine Self-Administration in Rodents.
abstract: Nicotine addiction is a complex process that begins with self-administration. Consequently, this process has been studied extensively using animal models. A person is usually not called "smoker" if s/he has smoked for a week or a month in a lifetime; in general, a smoker has been smoking for many years. Furthermore, a smoker has free access to cigarettes and can smoke whenever she/he wants, provided there are no social/legal restraints. Subsequently, in an animal model of tobacco addiction, it will be desirable to expose the animal to free access nicotine for 24 hours/day for many weeks, starting at different stages of development.
authors.affiliation: Institute for Behavioral Genetics, University of Colorado, Boulder, Colorado, USA.
authors.forename: Allan C
authors.initials: AC
authors.lastname: Collins
authors.forename: Sakire
authors.initials: S
authors.lastname: Pogun
authors.forename: Tanseli
authors.initials: T
authors.lastname: Nesil
authors.forename: Lutfiye
authors.initials: L
authors.lastname: Kanit