title: Interaction of cytochrome c with zinc oxide nanoparticles.
abstract: The influence of pH on the interaction between horse heart ferricytochrome c (cyt c) and zinc oxide nanoparticles (ZnO NPs) has been studied by a small angle scattering as well as UV-vis and FTIR spectroscopy. The observations showed that the optimal pH for the association of protein with nanoparticles is in pH range 5.0-8.0. Almost no significant change in structure and thermodynamic stability of cytochrome c after the association with 60 nm ZnO NPs was performed by UV-vis and by a circular dichroism spectroscopy.
authors.affiliation: Department of Biochemistry, Faculty of Science, PJ Šafárik University, Šrobárova 2, 041 54 Košice, Slovakia.
authors.forename: Michaela
authors.initials: M
authors.lastname: Šimšíková
authors.forename: Marián
authors.initials: M
authors.lastname: Antalík
mesh_terms: D000327:Adsorption; D000818:Animals; D002942:Circular Dichroism; D045304:Cytochromes c / Q000378:metabolism*; D006736:Horses; D006863:Hydrogen-Ion Concentration; D018625:Microscopy, Atomic Force; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D011485:Protein Binding; D017550:Spectroscopy, Fourier Transform Infrared; D055672:Static Electricity; D013696:Temperature; D015034:Zinc Oxide / Q000378:metabolism*
chemical_list: D045304:Cytochromes c; D015034:Zinc Oxide