title: Genetic analysis of glycopeptide-resistant Staphylococcus epidermidis strains from bone and joint infections.
abstract: Glycopeptide-resistant Staphylococcus epidermidis (GRSE) strains are of increasing concern in bone and joint infections (BJIs). Using multilocus sequence typing and multilocus variable-number tandem repeat analysis, we show that BJI-associated GRSE strains are genetically diverse but arise from related, multiresistant hospital sequence types (STs), mostly ST2, ST5, and ST23.
authors.affiliation: EA3647, Université de Versailles Saint-Quentin-en-Yvelines, Garches, France.
authors.forename: Julie
authors.initials: J
authors.lastname: Cremniter
authors.forename: Valérie
authors.initials: V
authors.lastname: Sivadon-Tardy
authors.forename: Charlotte
authors.initials: C
authors.lastname: Caulliez
authors.forename: Thomas
authors.initials: T
authors.lastname: Bauer
authors.forename: Raphaël
authors.initials: R
authors.lastname: Porcher
authors.forename: Alain
authors.initials: A
authors.lastname: Lortat-Jacob
authors.forename: Philippe
authors.initials: P
authors.lastname: Piriou
authors.forename: Thierry
authors.initials: T
authors.lastname: Judet
authors.forename: Philippe
authors.initials: P
authors.lastname: Aegerter
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Herrmann
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Gaillard
authors.forename: Martin
authors.initials: M
authors.lastname: Rottman
mesh_terms: D000328:Adult; D000368:Aged; D001168:Arthritis / Q000453:epidemiology / Q000382:microbiology*; D016000:Cluster Analysis; D024881:Drug Resistance, Bacterial; D005260:Female; D014644:Genetic Variation; D005838:Genotype; D006020:Glycopeptides / Q000494:pharmacology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018598:Minisatellite Repeats; D017720:Molecular Epidemiology; D058885:Multilocus Sequence Typing; D010019:Osteomyelitis / Q000453:epidemiology / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D013212:Staphylococcus epidermidis / Q000145:classification / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification
chemical_list: D006020:Glycopeptides