title: The impact of common variation in the definition of diabetic sensorimotor polyneuropathy on the validity of corneal in vivo confocal microscopy in patients with type 1 diabetes: a brief report.
abstract: The consensus definition for diabetic sensorimotor polyneuropathy allows for subtle variation in specific diagnostic criteria. In 89 type 1 diabetes participants, we found that common variations in these criteria do not impact the diagnostic validity of corneal nerve fiber length, a parameter of corneal in vivo confocal microscopy.
authors.affiliation: Division of Endocrinology and Metabolism, Department of Medicine, University of Toronto, Toronto, Canada.
authors.forename: Elise M
authors.initials: EM
authors.lastname: Halpern
authors.forename: Leif E
authors.initials: LE
authors.lastname: Lovblom
authors.forename: Steven
authors.initials: S
authors.lastname: Orlov
authors.forename: Ausma
authors.initials: A
authors.lastname: Ahmed
authors.forename: Vera
authors.initials: V
authors.lastname: Bril
authors.forename: Bruce A
authors.initials: BA
authors.lastname: Perkins
mesh_terms: D000328:Adult; D015415:Biomarkers; D015331:Cohort Studies; D003315:Cornea / Q000294:innervation / Q000473:pathology*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003929:Diabetic Neuropathies / Q000150:complications*; D003930:Diabetic Retinopathy / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D008297:Male; D018613:Microscopy, Confocal; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology*; D011115:Polyneuropathies / Q000150:complications*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D015415:Biomarkers