title: Design standards for engineered tissues.
abstract: Traditional technologies are required to meet specific, quantitative standards of safety and performance. In tissue engineering, similar standards will have to be developed to enable routine clinical use and customized tissue fabrication. In this essay, we discuss a framework of concepts leading towards general design standards for tissue-engineering, focusing in particular on systematic design strategies, control of cell behavior, physiological scaling, fabrication modes and functional evaluation.
authors.affiliation: Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA. jnawroth@caltech.edu
authors.forename: Janna C
authors.initials: JC
authors.lastname: Nawroth
authors.forename: Kevin Kit
authors.initials: KK
authors.lastname: Parker
mesh_terms: D035843:Biomedical Research; D001709:Biotechnology; D023822:Tissue Engineering / Q000379:methods* / Q000592:standards*