title: [Study on therapeutical effect of Canghuopingwei granules on chronic gastritis in rats].
abstract: OBJECTIVE
  To investigate the therapeutical effect of Canghuopingwei Granules on chronic gastritis in rats.
  
  
  METHODS
  Rat models of chronic gastritis and bile reflux gastritis were used. After rat models were established, the rats were divided into 6 groups and were treated with different drugs. The tissue samples were obtained after one week. The volume of gastric juice, acidity of gastric juice and pepsase activity were determined, and changes of the gastric mucosa were studied by microscopy.
  
  
  RESULTS
  The acidity of gastric juice was reversed with Canghuopingwei granules treatment. Gastric pathologic examination suggested that Canghuopingwei granules could markedly attenuate the pathological changes of gastric mucosa in rats.
  
  
  CONCLUSIONS
  Canghuopingwei granules has remarkably therapeutical effect on chronic gastritis and bile reflux gastritis in rats.
authors.affiliation: Chemical Engineering, Hefei University of Technology, Hefei 230009, China. feizixiao1987@163.com
authors.forename: Fei-Fei
authors.initials: FF
authors.lastname: Xu
authors.forename: Shou-Shan
authors.initials: SS
authors.lastname: Ye
authors.forename: Xiao-Xiang
authors.initials: XX
authors.lastname: Zhang
mesh_terms: D000284:Administration, Oral; D000818:Animals; D031174:Atractylodes / Q000737:chemistry; D001655:Bile Reflux / Q000188:drug therapy* / Q000473:pathology; D002908:Chronic Disease; D004195:Disease Models, Animal; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D005744:Gastric Acid / Q000378:metabolism; D005745:Gastric Acidity Determination; D005750:Gastric Juice / Q000187:drug effects; D005753:Gastric Mucosa / Q000187:drug effects / Q000473:pathology; D005756:Gastritis / Q000188:drug therapy* / Q000473:pathology; D006863:Hydrogen-Ion Concentration; D008297:Male; D008517:Phytotherapy; D010946:Plants, Medicinal / Q000737:chemistry; D051381:Rats
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal