title: Sesquiterpene lactones from the roots of Lindera strychnifolia.
abstract: Phytochemical investigation of the roots of Lindera strychnifolia resulted in the isolation of seven sesquiterpene lactones named linderolide G-M (1-7), together with twelve known sesquiterpenes. The structures and relative configurations of 1-7 were determined through spectroscopic observations, and the absolute configurations were defined by CD analysis. Linderolide G (1) and lindestrene (16) showed cytotoxicity against HSC-T6 hepatic stellate cells.
authors.affiliation: College of Pharmacy, Chungbuk National University, Heungduk-gu, Cheongju, Republic of Korea.
authors.forename: Qing
authors.initials: Q
authors.lastname: Liu
authors.forename: Jong Hoon
authors.initials: JH
authors.lastname: Ahn
authors.forename: Seon Beom
authors.initials: SB
authors.lastname: Kim
authors.forename: Chul
authors.initials: C
authors.lastname: Lee
authors.forename: Bang Yeon
authors.initials: BY
authors.lastname: Hwang
authors.forename: Mi Kyeong
authors.initials: MK
authors.lastname: Lee
mesh_terms: D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D007783:Lactones / Q000737:chemistry* / Q000494:pharmacology*; D027443:Lindera / Q000737:chemistry*; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry*; D051381:Rats; D012717:Sesquiterpenes / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D007783:Lactones; D012717:Sesquiterpenes