title: Comparison of different advanced oxidation processes for the degradation of two fluoroquinolone antibiotics in aqueous solutions.
abstract: In this study a comparative assessment using various advanced oxidation processes (UV/H(2)O(2), UV/H(2)O(2)/Fe(II), O(3), O(3)/UV, O(3)/UV/H(2)O(2) and O(3)/UV/H(2)O(2)/Fe(II)) was attempted to degrade efficiently two fluoroquinolone drugs ENR [enrofloxacin (1-Cyclopropyl-7-(4-ethyl-1-piperazinyl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolonecarboxylic acid)] and CIP [ciprofloxacin (1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-quinoline-3-carboxylic acid)] in aqueous solutions at a concentrations of 0.15 mM for each drug. The efficiency of the applied oxidation processes (AOPs) has been estimated by the conversion of the original substrate (X(ENR) and X(CIP)) and the reduction of chemical oxygen demand (COD), total organic carbon (TOC). Special emphasis was laid on the effect of varying reaction pH as well as of the applied oxidant doses on the observed reaction kinetics for each advanced oxidation processes. High degradation efficiencies, particularly in terms of rates of TOC and COD abatement, were obtained for photo-Fenton assisted ozonation [O(3)/UV/H(2)O(2)/Fe(II)], compared to other advanced oxidation processes. At pH 3 and 25°C best results for the degradation of both investigated drugs were achieved when 10 mM H(2)O(2), 0.5 mM Fe(II) and an initial dose of 8.5 mg L(-1) ozone were applied. In addition, the evolution of toxicity of the reaction mixtures for different AOPs has been studied by the bioluminescence test (LUMIStox 300).
authors.affiliation: University of Suceava, Faculty of Food Engineering, Suceava, Romania.
authors.forename: Maria
authors.initials: M
authors.lastname: Bobu
authors.forename: Ayfer
authors.initials: A
authors.lastname: Yediler
authors.forename: Ilie
authors.initials: I
authors.lastname: Siminiceanu
authors.forename: Feifang
authors.initials: F
authors.lastname: Zhang
authors.forename: Sigurd
authors.initials: S
authors.lastname: Schulte-Hostede
mesh_terms: D000890:Anti-Infective Agents / Q000378:metabolism*; D001673:Biodegradation, Environmental; D002939:Ciprofloxacin / Q000378:metabolism*; D000077422:Enrofloxacin; D052918:Environmental Restoration and Remediation / Q000379:methods*; D024841:Fluoroquinolones / Q000378:metabolism*; D049449:Luminescence; D010084:Oxidation-Reduction; D010126:Ozone / Q000737:chemistry; D010782:Photolysis; D014874:Water Pollutants, Chemical / Q000378:metabolism*
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D014874:Water Pollutants, Chemical; D000077422:Enrofloxacin; D002939:Ciprofloxacin; D010126:Ozone