title: Early presentation of neuromyelitis optica.
abstract: Neuromyelitis optica is a rare autoimmune demyelinating disease of the central nervous system in childhood. Its relapsing form is usually reported in adults.  We report a 3-year-old girl with relapsing, IgG seropositive neuromyelitis optica. Initially she presented with optic neuritis, followed by three relapses with deterioration of optic neuritis and developing transverse myelitis.  With each relapse, the treatment was less effective. Four years after the onset of the disease, the patient was blind, had paraplegia associated with urinary and bowel incontinence and short stature.
authors.affiliation: Department of Neurology, University Childrens Hospital, and Medical Faculty University of Belgrade, 11000 Belgrade, Serbia. ndimitrijevic@beotel.net
authors.forename: Nikola
authors.initials: N
authors.lastname: Dimitrijevic
authors.forename: Dragana
authors.initials: D
authors.lastname: Bogicevic
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Dimitrijevic
authors.forename: Dimitrije
authors.initials: D
authors.lastname: Nikolic
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009471:Neuromyelitis Optica / Q000175:diagnosis* / Q000473:pathology; D012008:Recurrence; D013116:Spinal Cord / Q000473:pathology