title: The obstetric and neonatal implications of a low value on the 50-g glucose screening test.
abstract: OBJECTIVE
  To assess the relationship between a low 50-g 1-hour glucose loading test (GLT) and maternal and neonatal outcomes in women without diabetes.
  
  
  METHODS
  This was a secondary analysis of a multicenter observational cohort from a randomized trial of treatment for mild gestational diabetes. Maternal and neonatal outcomes were compared between women with GLT values < 90 mg/dL and those with results 90 to 119 mg/dL.
  
  
  RESULTS
  Of 436 enrolled women, 297 (68.1%) had a GLT result of 90 to 119 mg/dL and 139 (31.9%) had a result of < 90 mg/dL. There was a lower incidence of neonatal hypoglycemia in those with a GLT < 90 mg/dL (5.7% versus 16.5%, p = 0.006). Other outcomes were not associated with test results.
  
  
  CONCLUSIONS
  A GLT result < 90 mg/dL compared with 90 to 119 mg/dL is associated with a lower risk of neonatal hypoglycemia, but no other significant findings.
authors.affiliation: Department of Obstetrics and Gynecology of the Oregon Health and Science University, Portland, Oregon.
authors.forename: Kimberly K
authors.initials: KK
authors.lastname: Ma
authors.forename: Lisa
authors.initials: L
authors.lastname: Mele
authors.forename: Mark B
authors.initials: MB
authors.lastname: Landon
authors.forename: Catherine Y
authors.initials: CY
authors.lastname: Spong
authors.forename: Susan M
authors.initials: SM
authors.lastname: Ramin
authors.forename: Brian
authors.initials: B
authors.lastname: Casey
authors.forename: Ronald J
authors.initials: RJ
authors.lastname: Wapner
authors.forename: Michael W
authors.initials: MW
authors.lastname: Varner
authors.forename: Dwight J
authors.initials: DJ
authors.lastname: Rouse
authors.forename: John M
authors.initials: JM
authors.lastname: Thorp
authors.forename: Anthony
authors.initials: A
authors.lastname: Sciscione
authors.forename: Patrick
authors.initials: P
authors.lastname: Catalano
authors.forename: Margaret
authors.initials: M
authors.lastname: Harper
authors.forename: George
authors.initials: G
authors.lastname: Saade
authors.forename: Steve N
authors.initials: SN
authors.lastname: Caritis
authors.forename: Yoram
authors.initials: Y
authors.lastname: Sorokin
authors.forename: Alan M
authors.initials: AM
authors.lastname: Peaceman
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D055815:Young Adult; D019540:Area Under Curve; D001786:Blood Glucose / Q000378:metabolism; D005951:Glucose Tolerance Test; D007003:Hypoglycemia / Q000151:congenital / Q000175:diagnosis / Q000453:epidemiology; D015994:Incidence; D011248:Pregnancy Complications / Q000175:diagnosis; D011295:Prenatal Care; D012372:ROC Curve; D000094422:Secondary Data Analysis
chemical_list: D001786:Blood Glucose