title: Comparing the rate of regression after conductive keratoplasty with or without prior laser-assisted in situ keratomileusis or photorefractive keratectomy.
abstract: OBJECTIVE
  To assess the regression rate of conductive keratoplasty (CK) in patients with or without previous laser-assisted in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK).
  
  
  METHODS
  University of Utah, Medical School, John A. Moran Eye Center, Salt Lake City, Utah.
  
  
  METHODS
  A retrospective, age-matched chart review identified records of 6 patients who underwent CK after refractive surgery and 12 patients who underwent CK without prior refractive surgery. The main outcome measures were postoperative uncorrected and corrected visual acuities and refraction changes over time.
  
  
  RESULTS
  Preoperatively, the mean manifest refraction spherical equivalent (MRSE) of the 15 eyes (12 patients) that underwent CK without refractive surgery was 0.83 diopters (D) and the 7 eyes (6 patients) that underwent CK after refractive surgery had an average MRSE of 0.27 D. Postoperatively, the mean MRSE of the refractive surgery patients was -0.86 D at 6 months, regressing to -0.67 D at 12 months. The postoperative MRSE in the eyes without refractive surgery was -0.58 D. at 6 months, regressing to -0.38 D at 12 months. The rate of regression was linear in both groups, calculated at 0.033 D per month in all patients.
  
  
  CONCLUSIONS
  Patients with previous LASIK or PRK showed a greater treatment response to CK but regressed at a similar rate as those eyes without prior LASIK or PRK. Overall CK is a safe procedure that inevitably regresses.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Utah, John A Moran Eye Center, Salt Lake City, UT, USA.
authors.forename: Majid
authors.initials: M
authors.lastname: Moshirfar
authors.forename: Erik
authors.initials: E
authors.lastname: Anderson
authors.forename: Maylon
authors.initials: M
authors.lastname: Hsu
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Armenia
authors.forename: Mark D
authors.initials: MD
authors.lastname: Mifflin
mesh_terms: D001251:Astigmatism / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D008297:Male; D008875:Middle Aged; D018903:Photorefractive Keratectomy / Q000379:methods*; D011305:Presbyopia / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D012029:Refraction, Ocular; D012189:Retrospective Studies; D016896:Treatment Outcome