title: Species-specific differences in the accumulation features of organohalogen contaminants and their metabolites in the blood of Japanese terrestrial mammals.
abstract: Residue levels and patterns of polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), their hydroxylated metabolites (OH-PCBs, OH-PBDEs), and methoxylated PBDEs (MeO-PBDEs) in the blood of various terrestrial mammals in Japan, including cats, raccoon dogs, dogs, masked palm civets, foxes, raccoons, badgers, and mongooses were determined. Tri- through penta-chlorinated OH-PCBs were predominant in cat blood, whereas hexa- through octa-chlorinated OH-PCBs were found in other species. High proportion of BDE209 was found in all species, suggesting exposure to municipal waste and soil containing higher levels of deca-BDE products. 6OH-/MeO-BDE47 and 2'OH-/MeO-BDE68 were dominant in all terrestrial mammals. This is first report on the detection of OH-/MeO-PBDEs in the blood of terrestrial mammals. High concentrations of OH-/MeO-PBDEs were found in cats, suggesting the intake of these compounds from seafood. Cats exhibited higher accumulation and specific patterns of OH-PCBs, OH-PBDEs, and MeO-PBDEs, they may be at a high risk from these metabolites.
authors.affiliation: Center for Marine Environmental Studies (CMES), Ehime University, Matsuyama, Ehime 790-8577, Japan.
authors.forename: Hazuki
authors.initials: H
authors.lastname: Mizukawa
authors.forename: Kei
authors.initials: K
authors.lastname: Nomiyama
authors.forename: Susumu
authors.initials: S
authors.lastname: Nakatsu
authors.forename: Shuuji
authors.initials: S
authors.lastname: Yachimori
authors.forename: Terutake
authors.initials: T
authors.lastname: Hayashi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Tashiro
authors.forename: Yasuko
authors.initials: Y
authors.lastname: Nagano
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Tanabe
mesh_terms: D000818:Animals; D002415:Cats / Q000097:blood; D004285:Dogs / Q000097:blood; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000097:blood*; D004787:Environmental Pollution / Q000706:statistics & numerical data; D005589:Foxes / Q000097:blood; D055768:Halogenated Diphenyl Ethers / Q000097:blood*; D008988:Herpestidae / Q000097:blood; D007564:Japan; D008322:Mammals / Q000097:blood*; D045969:Mustelidae / Q000097:blood; D011078:Polychlorinated Biphenyls / Q000097:blood*; D046031:Raccoon Dogs / Q000097:blood; D011821:Raccoons / Q000097:blood; D045949:Viverridae / Q000097:blood
chemical_list: D004785:Environmental Pollutants; D055768:Halogenated Diphenyl Ethers; D011078:Polychlorinated Biphenyls