title: Isolated intraspinal juvenile xanthogranuloma in an infant presenting as acute paraplegia.
abstract: Juvenile xanthogranuloma is a histiocytic proliferative disease that predominantly affects the skin. Extracutaneous involvement is rare. We present the case of a 6-month-old infant with acute paraplegia. Magnetic resonance imaging showed an intraspinal extradural mass at midthoracic level with marked compression of the spinal cord. Complete tumor removal was achieved by emergency surgery and was followed by complete neurologic recovery. Histologic examination led to the diagnosis of a juvenile xanthogranuloma. To the best of our knowledge, an isolated intraspinal juvenile xanthogranuloma in the first 12 months of life has not been described before.
authors.affiliation: Department of Neuropediatrics, University Children's Hospital Zurich, Zurich, Switzerland. david.wille@kispi.uzh.ch
authors.forename: David-Alexander
authors.initials: DA
authors.lastname: Wille
authors.forename: Oliver
authors.initials: O
authors.lastname: Bozinov
authors.forename: Ianina
authors.initials: I
authors.lastname: Scheer
authors.forename: Michael A
authors.initials: MA
authors.lastname: Grotzer
authors.forename: Eugen
authors.initials: E
authors.lastname: Boltshauser
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D010264:Paraplegia / Q000503:physiopathology*; D013116:Spinal Cord / Q000473:pathology*; D014972:Xanthogranuloma, Juvenile / Q000175:diagnosis / Q000503:physiopathology*