title: Plasma free amino acid profiles of canine mammary gland tumors.
abstract: The purpose of this study was to elucidate the relationship between plasma free amino acid (PFAA) levels and the clinical stages of mammary gland tumors (MGT) in dogs. PFAA levels in canines with malignant mammary tumors were decreased compared to those of healthy animals. The levels of aspartate and ornithine, in the dogs with tumor metastasis were significantly decreased when compared to those of dogs that did not have metastases. Results of this study indicate that PFAA levels could be a risk factor or biomarker for canine MGT metastasis.
authors.affiliation: School of Veterinary Medicine, Tottori University, Tottori 680-8553, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Azuma
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Osaki
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tsuka
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Imagawa
authors.forename: Saburo
authors.initials: S
authors.lastname: Minami
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Okamoto
mesh_terms: D000367:Age Factors; D000596:Amino Acids / Q000097:blood*; D000818:Animals; D001835:Body Weight; D004283:Dog Diseases; D004285:Dogs; D005260:Female; D015674:Mammary Neoplasms, Animal / Q000097:blood* / Q000235:genetics; D009362:Neoplasm Metastasis / Q000175:diagnosis* / Q000235:genetics; D009367:Neoplasm Staging / Q000662:veterinary; D012709:Serum Albumin; D012737:Sex Factors
chemical_list: D000596:Amino Acids; D012709:Serum Albumin