title: Langerhans cell histiocytosis followed by Hodgkin's lymphoma.
abstract: A 22-year-old man was referred to our institution due to lower back pain and was diagnosed with Langerhans cell histiocytosis of the thoracic and lumbar spine. The patient achieved complete remission with radiotherapy and chemotherapy. One year later, right cervical lymphadenopathy was observed and Hodgkin's lymphoma was confirmed on biopsy. The patient was treated with chemotherapy and autologous stem cell transplantation, and experienced no further symptoms. Further, no evidence of recurrence was observed on follow-up imaging. This report discusses the association between Langerhans cell histiocytosis and Hodgkin's lymphoma.
authors.affiliation: Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: Ik Soo
authors.initials: IS
authors.lastname: Park
authors.forename: In Keun
authors.initials: IK
authors.lastname: Park
authors.forename: Eun Kyoung
authors.initials: EK
authors.lastname: Kim
authors.forename: Shin
authors.initials: S
authors.lastname: Kim
authors.forename: Sang Ryong
authors.initials: SR
authors.lastname: Jeon
authors.forename: Joo Ryung
authors.initials: JR
authors.lastname: Huh
authors.forename: Cheol Won
authors.initials: CW
authors.lastname: Suh
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols; D003131:Combined Modality Therapy; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006689:Hodgkin Disease / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008297:Male; D033581:Stem Cell Transplantation; D055815:Young Adult