title: Reduction of neonatal pain following administration of 25% lingual dextrose: a randomized control trial.
abstract: Neonates experience painful procedures during routine care. Orally administered, sweet tasting solutions are commonly used in management of neonatal pain. We conducted a double-blind randomized control trial in neonates admitted to Neonatal Intensive Care Unit of Shri Krishna Hospital, Karamsad-Gujarat-India, of lingual administration of 25% dextrose vs. no intervention, to evaluate reduction of pain following oropharyngeal infant feeding tube insertions. Pain was assessed using Premature Infant Pain Profile score. Almost all the patients in the control group (98%) experienced moderate-to-severe pain as compared with the intervention group (71%). Mean Premature Infant Pain Profile score was statistically significantly lower in the intervention group (8.21) as compared with control group (10.31). (p < 0.001, 95% CI 1.090-3.102). Lingual 25% dextrose is an effective analgesic for relieving pain during orogastric tube insertion.
authors.affiliation: Department of Pediatrics, Pramukhswami Medical College, Karamsad 388325, Anand, Gujarat, India.
authors.forename: Somashekhar
authors.initials: S
authors.lastname: Nimbalkar
authors.forename: Ankit
authors.initials: A
authors.lastname: Sinojia
authors.forename: Ashish
authors.initials: A
authors.lastname: Dongara
mesh_terms: D004311:Double-Blind Method; D005260:Female; D005947:Glucose / Q000008:administration & dosage*; D006801:Humans; D007194:India; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D008297:Male; D010146:Pain / Q000517:prevention & control*; D059408:Pain Management / Q000379:methods*; D010147:Pain Measurement / Q000379:methods; D011247:Pregnancy; D013549:Sweetening Agents / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D013549:Sweetening Agents; D005947:Glucose