title: Clear lens phacoemulsification combined with vitrectomy to correct high myopia: four years of follow-up.
abstract: OBJECTIVE
  To evaluate the outcome, intraoperative and postoperative complications of refractive lens exchange (RLE) by phacoemulsification with posterior chamber intraocular lens (IOL) implantation combined with simultaneous pars plana vitrectomy (PPV) in the management of high myopia.
  
  
  METHODS
  This prospective study consisted of 45 eyes of 26 patients with preoperative myopia greater than -12.5 dpt. Clear lens phacoemulsification with IOL implantation surgery was combined with PPV. Main outcome measures were best-corrected visual acuity (BCVA), stability of the spherical equivalent (SE) and complications at follow-up.
  
  
  RESULTS
  The combined procedure of clear lens phacoemulsification combined with PPV has a favorable outcome with acceptable SE predictability and improvement in BCVA. The postoperative BCVA was 0.67 ± 0.21 compared to 0.15 ± 0.10 preoperatively (p < 0.001). The mean postoperative SE was -1.6 ± 0.9 dpt, showing a significant difference when compared with a mean value of -20.0 ± 5.2 dpt before the operation (p < 0.001). During the follow-up, all IOLs were placed stably in the bag with no capsular tear occurring and only 1 case (2.2%) developed retinal detachment.
  
  
  CONCLUSIONS
  RLE and implantation of an IOL combined with simultaneous PPV is a reasonable refractive surgery option for middle-aged patients with high myopia.
authors.affiliation: Eye Hospital, Wenzhou Medical College, Wenzhou, PR China.
authors.forename: Qinxiang
authors.initials: Q
authors.lastname: Zheng
authors.forename: Ronghan
authors.initials: R
authors.lastname: Wu
authors.forename: Shelley
authors.initials: S
authors.lastname: Yang
authors.forename: Yuanping
authors.initials: Y
authors.lastname: Zhang
authors.forename: Wensheng
authors.initials: W
authors.lastname: Li
mesh_terms: D000328:Adult; D058442:Capsule Opacification / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007431:Intraoperative Complications; D053844:Lasers, Solid-State; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000503:physiopathology / Q000601:surgery*; D018918:Phacoemulsification; D057852:Posterior Capsule of the Lens / Q000601:surgery; D011183:Postoperative Complications; D011446:Prospective Studies; D019591:Pseudophakia / Q000503:physiopathology; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy