title: Regulation of breast cancer tumorigenesis and metastasis by miRNAs.
abstract: miRNAs are a family of 17- to 23-nucleotide noncoding small RNAs that primarily function as gene expression fine regulators. A number of studies have shown that miRNAs play an important role in breast tumorigenesis, metastasis, proliferation and differentiation of breast cancer stem cells. This short review summarizes the progression of miRNA-mediated breast tumorigenesis and metastasis through various signaling pathways associated with drug resistance.
authors.affiliation: Dalian Medical University, Dalian, 116000, China.
authors.forename: Lianhong
authors.initials: L
authors.lastname: Li
authors.forename: Bowen
authors.initials: B
authors.lastname: Xiao
authors.forename: Hanna
authors.initials: H
authors.lastname: Tong
authors.forename: Fangpei
authors.initials: F
authors.lastname: Xie
authors.forename: Zhong
authors.initials: Z
authors.lastname: Zhang
authors.forename: Gary Guishan
authors.initials: GG
authors.lastname: Xiao
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology*; D002454:Cell Differentiation; D049109:Cell Proliferation; D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D019008:Drug Resistance, Neoplasm; D005260:Female; D006801:Humans; D035683:MicroRNAs / Q000502:physiology*; D009362:Neoplasm Metastasis / Q000235:genetics*
chemical_list: D035683:MicroRNAs