title: Unusual macular thickness in Alport syndrome: case report.
abstract: This case report describes the presence of bilateral macular atrophy in a patient with Alport syndrome and compares this finding with literature. At fundoscopy, there was a discrete circumscribed macular thinning showing intense retinal pigment epithelium color and the presence of whitish circular retinal lesions ("dots" and "flecks") at nasal mid periphery of both eyes. Optical coherence tomography showed bilateral partial atrophy of the neurosensory retina in the macula, with a greater extent in the temporal region. This case describes a rare ophthalmological finding in Alport syndrome and important to be recognized for a precise diagnosis as well as for determining visual prognosis.
authors.affiliation: Vitreoretinal Diseases Service, Department of Ophthalmology, Hospital das Clínicas, Universidade de São Paulo - USP - São Paulo (SP), Brazil. thais_igami@hotmail.com
authors.forename: Thais Z
authors.initials: TZ
authors.lastname: Igami
authors.forename: Marcelo M
authors.initials: MM
authors.lastname: Lavezzo
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Ferraz
authors.forename: Walter Y
authors.initials: WY
authors.lastname: Takahashi
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Nakashima
mesh_terms: D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000175:diagnosis / Q000235:genetics*; D008875:Middle Aged; D009394:Nephritis, Hereditary / Q000150:complications*; D012160:Retina / Q000002:abnormalities*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity