title: Patterns of gene expression in microarrays and expressed sequence tags from normal and cataractous lenses.
abstract: In this contribution, we have examined the patterns of gene expression in normal and cataractous lenses as presented in five different papers using microarrays and expressed sequence tags. The purpose was to evaluate unique and common patterns of gene expression during development, aging and cataracts.
authors.affiliation: Department of Biology and Center for Tissue Regeneration and Engineering, University of Dayton, Dayton, OH 45469-2320, USA.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Sousounis
authors.forename: Panagiotis A
authors.initials: PA
authors.lastname: Tsonis
mesh_terms: D000375:Aging / Q000235:genetics; D000818:Animals; D002386:Cataract / Q000235:genetics* / Q000473:pathology; D016000:Cluster Analysis; D020224:Expressed Sequence Tags / Q000378:metabolism*; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D056726:Genetic Association Studies; D006801:Humans; D007109:Immunity / Q000235:genetics; D007908:Lens, Crystalline / Q000378:metabolism* / Q000473:pathology*; D051379:Mice; D020411:Oligonucleotide Array Sequence Analysis; D015676:Osteonectin / Q000172:deficiency / Q000378:metabolism; D012326:RNA Splicing / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism
chemical_list: D015676:Osteonectin; D012333:RNA, Messenger