title: [The function of palatine tonsils in pathological changes of oral mucosa and the possibilities of immunorehabilitation].
abstract: The objective of the present study was to estimate the possibility of using imudon for the treatment of chronic generalized periodontitis (CGP) in the patients presenting with various forms of chronic tonsillitis (CT) based on the results of the study of local immunity of the oropharynx. A total of 92 patients with CGP were divided into 3 groups as follows: those without pathology of palatine tonsils (PT) (group 1), cases with compensated chronic tonsillitis (group 2), and patients with periodontitis and concomitant decompensated form of CT (paratonsilitis). The results of assessment of local immunity (from the analysis of immunocytograms of the PT surface and periodontal pockets along with the data on the immunoglobulin content in mixed saliva samples and blood plasma) give evidence of the specific features of local immune responsiveness depending on the state of palatine tonsils. The changes of local immunity characteristics after the treatment suggest the efficacy of the traditional treatment of chronic generalized periodontitis in the absence of NT pathology and the necessity of its supplementation with imudon herapy in the patients with CGP and compensated form of CT.
authors.forename: M I
authors.initials: MI
authors.lastname: Gumerova
authors.forename: L F
authors.initials: LF
authors.lastname: Aznabaeva
authors.forename: N A
authors.initials: NA
authors.lastname: Aref'eva
mesh_terms: D002908:Chronic Disease; D006801:Humans; D018928:Immunity, Mucosal; D007167:Immunotherapy / Q000379:methods*; D009061:Mouth Mucosa / Q000276:immunology* / Q000473:pathology; D014066:Palatine Tonsil / Q000276:immunology*; D010518:Periodontitis / Q000150:complications* / Q000276:immunology / Q000628:therapy; D014069:Tonsillitis / Q000150:complications* / Q000276:immunology / Q000628:therapy