title: A clinical review of small-cell carcinoma of the urinary bladder.
abstract: Small-cell carcinoma of the urinary bladder is a rare and aggressive type of bladder cancer that has a poor prognosis. The incidence has been gradually increasing because of the aging population. Owing to its rarity there are no available treatment guidelines. Several retrospective studies and 1 prospective study have provided some insight into therapy for this disease. A multimodal approach that includes chemotherapy, local radiation therapy, and definitive surgery in resectable cases appears to be an optimal management approach.
authors.affiliation: Department of Internal Medicine, Fairview Hospital, Cleveland Clinic Hospitals, Cleveland, OH 44111, USA. thotas@ccf.org
authors.forename: Swapna
authors.initials: S
authors.lastname: Thota
authors.forename: Gaurav
authors.initials: G
authors.lastname: Kistangari
authors.forename: Hamed
authors.initials: H
authors.lastname: Daw
authors.forename: Timothy
authors.initials: T
authors.lastname: Spiro
mesh_terms: D018288:Carcinoma, Small Cell / Q000453:epidemiology / Q000401:mortality / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology / Q000401:mortality / Q000628:therapy