title: Benign clinical course in H1N1 2009 influenza infection in young oseltamivir-treated immunocompromised patients with kidney disease in Singapore.
abstract: This report describes the clinical features of H1N1 2009 influenza infection in 10 young renal patients receiving chronic dialysis or immunosuppressants, and to compare their durations of viral shedding with 20 healthy controls. Although patients shed the virus for longer periods compared with controls, all had a self-limited clinical course. Studies on indications, dosages and durations of antiviral therapy in renal and immunocompromised patients are warranted.
authors.affiliation: National University of Singapore, Singapore. paenkh@nus.edu.sg
authors.forename: Kar-Hui
authors.initials: KH
authors.lastname: Ng
authors.forename: Zhi-Xuan
authors.initials: ZX
authors.lastname: Quak
authors.forename: Yiong-Huak
authors.initials: YH
authors.lastname: Chan
authors.forename: Mas
authors.initials: M
authors.lastname: Suhaila
authors.forename: Perry Yew-Weng
authors.initials: PY
authors.lastname: Lau
authors.forename: Paul Anantharajah
authors.initials: PA
authors.lastname: Tambyah
authors.forename: Julian Wei-Tze
authors.initials: JW
authors.lastname: Tang
authors.forename: Hui-Kim
authors.initials: HK
authors.lastname: Yap
mesh_terms: D000293:Adolescent; D000998:Antiviral Agents / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000188:drug therapy* / Q000473:pathology* / Q000821:virology; D007674:Kidney Diseases / Q000150:complications* / Q000628:therapy; D008297:Male; D053139:Oseltamivir / Q000008:administration & dosage*; D006435:Renal Dialysis; D012846:Singapore; D013997:Time Factors; D016896:Treatment Outcome; D017201:Virus Shedding; D055815:Young Adult
chemical_list: D000998:Antiviral Agents; D053139:Oseltamivir