title: Cauda equina syndrome caused by pseudogout involving the lumbar intervertebral disc.
abstract: Calcium pyrophosphate dihydrate (CPPD) deposition disease, also known as pseudogout, is a disease that causes inflammatory arthropathy in peripheral joints, however, symptomatic involvement of the intervertebral disc is uncommon. Herein, we describe a 59-yr-old patient who presented with cauda equina syndrome. Magnetic resonance imaging of the patient showed an epidural mass-like lesion at the disc space of L4-L5, which was compressing the thecal sac. Biopsy of the intervertebral disc and epidural mass-like lesion was determined to be CPPD deposits. We reviewed previously reported cases of pseudogout involving the lumbar intervertebral disc and discuss the pathogenesis and treatment of the disease.
authors.affiliation: Department of Neurosurgery Dongguk University Ilsan Hospital, Goyang, Korea.
authors.forename: Jungjun
authors.initials: J
authors.lastname: Lee
authors.forename: Keun-Tae
authors.initials: KT
authors.lastname: Cho
authors.forename: Eo-Jin
authors.initials: EJ
authors.lastname: Kim
mesh_terms: D002131:Calcium Pyrophosphate / Q000378:metabolism; D002805:Chondrocalcinosis / Q000209:etiology; D017586:Diskectomy; D006801:Humans; D007403:Intervertebral Disc / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011128:Polyradiculopathy / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D002131:Calcium Pyrophosphate