title: MIRIAD--Public release of a multiple time point Alzheimer's MR imaging dataset.
abstract: The Minimal Interval Resonance Imaging in Alzheimer's Disease (MIRIAD) dataset is a series of longitudinal volumetric T1 MRI scans of 46 mild-moderate Alzheimer's subjects and 23 controls. It consists of 708 scans conducted by the same radiographer with the same scanner and sequences at intervals of 2, 6, 14, 26, 38 and 52 weeks, 18 and 24 months from baseline, with accompanying information on gender, age and Mini Mental State Examination (MMSE) scores. Details of the cohort and imaging results have been described in peer-reviewed publications, and the data are here made publicly available as a common resource for researchers to develop, validate and compare techniques, particularly for measurement of longitudinal volume change in serially acquired MR.
authors.affiliation: Dementia Research Centre, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
authors.forename: Ian B
authors.initials: IB
authors.lastname: Malone
authors.forename: David
authors.initials: D
authors.lastname: Cash
authors.forename: Gerard R
authors.initials: GR
authors.lastname: Ridgway
authors.forename: David G
authors.initials: DG
authors.lastname: MacManus
authors.forename: Sebastien
authors.initials: S
authors.lastname: Ourselin
authors.forename: Nick C
authors.initials: NC
authors.lastname: Fox
authors.forename: Jonathan M
authors.initials: JM
authors.lastname: Schott
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis; D005260:Female; D006801:Humans; D033181:Information Dissemination; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging; D008297:Male; D013997:Time Factors