title: Angiosarcoma in a patient with congenital nonhereditary lymphedema.
abstract: Angiosarcoma is an uncommon but aggressive tumor of endothelial origin that may occur in the upper extremities of patients with postmastectomy lymphedema (Stewart-Treves syndrome) as well as in other regions. We present an unusual case of angiosarcoma associated with congenital nonhereditary lymphedema in an 18-year-old man. Our case underscores the need for a careful clinical examination and shows the importance of appropriate sampling and thorough pathologic examination of suspicious areas to exclude the presence of a malignant process.
authors.affiliation: Divison of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.
authors.forename: Wonwoo
authors.initials: W
authors.lastname: Shon
authors.forename: David A
authors.initials: DA
authors.lastname: Wada
authors.forename: Andrew L
authors.initials: AL
authors.lastname: Folpe
authors.forename: Mark R
authors.initials: MR
authors.lastname: Pittelkow
mesh_terms: D000293:Adolescent; D000671:Amputation, Surgical; D005534:Foot Diseases / Q000473:pathology* / Q000601:surgery; D006394:Hemangiosarcoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007866:Leg / Q000601:surgery; D008209:Lymphedema / Q000150:complications* / Q000151:congenital* / Q000473:pathology; D008297:Male; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery