title: Pharmacogenetics in clinical practice.
abstract: Pharmacogenetics is a discipline that investigates how genetic           variation relates to the drug efficacy and safety. The goal of pharmacogenetics           is a personalized treatment, where according to genotype we would be able           to prescribe the most effective drug at the most appropriate dose for an           individual patient. The aim of this review is to summarize pharmacogenetics as a           specialization with its own background, research, methods, including barriers and           promises for the future.
authors.affiliation: Institute of Pharmacology, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic. hana.vondrackova@centrum.cz
authors.forename: H
authors.initials: H
authors.lastname: Bakhouche
authors.forename: O
authors.initials: O
authors.lastname: Slanař
mesh_terms: D006801:Humans; D004364:Pharmaceutical Preparations; D010597:Pharmacogenetics; D011110:Polymorphism, Genetic; D057285:Precision Medicine
chemical_list: D004364:Pharmaceutical Preparations