title: Engineering novel detectors and sensors for MRI.
abstract: Increasing detection sensitivity and image contrast have always been major topics of research in MRI. In this perspective, we summarize two engineering approaches to make detectors and sensors that have potential to extend the capability of MRI. The first approach is to integrate miniaturized detectors with a wireless powered parametric amplifier to enhance the detection sensitivity of remotely coupled detectors. The second approach is to microfabricate contrast agents with encoded multispectral frequency shifts, whose properties can be specified and fine-tuned by geometry. These two complementary approaches will benefit from the rapid development in nanotechnology and microfabrication which should enable new opportunities for MRI.
authors.affiliation: National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Chunqi
authors.initials: C
authors.lastname: Qian
authors.forename: Gary
authors.initials: G
authors.lastname: Zabow
authors.forename: Alan
authors.initials: A
authors.lastname: Koretsky
mesh_terms: D000465:Algorithms; D000818:Animals; D003287:Contrast Media; D004574:Electromagnetic Fields; D004738:Engineering; D004867:Equipment Design; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D036103:Nanotechnology; D051381:Rats; D059015:Wireless Technology
chemical_list: D003287:Contrast Media