title: [A case report of locally recurrent rectal cancer after low anterior resection that led to a pathological complete response to neoadjuvant chemoradiotherapy].
abstract: We report a case of low anterior resection that led to a pathological complete response of locally recurrent rectal cancer to neoadjuvant chemoradiotherapy. A 57-year-old male patient underwent low anterior resection for rectal cancer pathologically diagnosed as type 2, tub2>tub1,pSS,INF b,int,ly2,v2,pPM0,pDM0,no,M0,H0,P0, and fStage II. After 2 years and 11 months, local recurrence of his rectal cancer was identified by colon fiberscopy. Neoadjuvant chemoradiotherapy was conducted with CPT-11, UFT/LV, and radiation(50 Gy),and this recurrent lesion exhibited a partial response to the chemoradiotherapy regimen according to magnetic resonance imaging findings. Then, we performed total pelvic exenteration, and the pathological examination revealed a pathological complete response.
authors.affiliation: Dept. of Surgery, Sakai City Hospital, Japan.
authors.forename: Ako
authors.initials: A
authors.lastname: Matsushita
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Takemoto
authors.forename: Masataka
authors.initials: M
authors.lastname: Ikeda
authors.forename: Tetsu
authors.initials: T
authors.lastname: Munakata
authors.forename: Mutsumi
authors.initials: M
authors.lastname: Fukunaga
authors.forename: Ryohei
authors.initials: R
authors.lastname: Kawabata
authors.forename: Tameyoshi
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Kazuyuki
authors.initials: K
authors.lastname: Oda
authors.forename: Tomono
authors.initials: T
authors.lastname: Kishimoto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Imamura
authors.forename: Hiroki
authors.initials: H
authors.lastname: Ohzato
mesh_terms: D059248:Chemoradiotherapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D012004:Rectal Neoplasms / Q000473:pathology / Q000628:therapy*; D012008:Recurrence