title: The influence of radiation therapy on dental implantology.
abstract: Patients with a history of head and neck cancer resection require extensive prosthodontic rehabilitation following cancer treatment. The oral anatomy drastically changes from ablative therapy, and the oral tissue response becomes altered as a consequence of radiation and chemotherapy. Successful restoration of oral function in this specific patient population was increasingly difficult before the widespread use of dental implants. Implant-borne prosthetics are now often used. However, surgical guidelines remain unclear with regard to oncology-related parameters. In this article, guidelines are introduced for implant therapy in the cancer patients according to radiation dosage and timing. Indications for hyperbaric oxygen treatment are highlighted along with risk assessment associated with implant placement. These guidelines are intended to augment knowledge obtained through oncology consultation; moreover, provide a rationale for implant therapy within the course of cancer treatment.
authors.affiliation: Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA.
authors.forename: Lauren
authors.initials: L
authors.lastname: Anderson
authors.forename: Stephen
authors.initials: S
authors.lastname: Meraw
authors.forename: Khalid
authors.initials: K
authors.lastname: Al-Hezaimi
authors.forename: Hom-Lay
authors.initials: HL
authors.lastname: Wang
mesh_terms: D003758:Dental Implantation, Endosseous / Q000379:methods*; D019094:Dental Prosthesis, Implant-Supported; D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D007571:Jaw Diseases / Q000209:etiology; D009055:Mouth / Q000528:radiation effects; D010025:Osteoradionecrosis / Q000209:etiology; D011879:Radiotherapy Dosage; D018570:Risk Assessment