title: Pre-operative assessment of living renal transplant donors with state-of-the-art imaging modalities: computed tomography angiography versus magnetic resonance angiography in 118 patients.
abstract: OBJECTIVE
  To compare current technology multislice computed tomography angiography (CTA) with magnetic resonance angiography (MRA) in the pre-operative evaluation of vascular anatomy of living renal transplant donors.
  
  
  METHODS
  Two hundred and thirty-six kidneys were included in the CTA and MRA analysis. Renal vasculature was evaluated independently by two readers in each modality with a delay of 4 weeks between reading sessions. Surgical correlation on the operated side was available in all patients. The reference standard was defined by surgical correlation and consensus reading of both modalities.
  
  
  RESULTS
  Detection rate of CTA for arteries was 99.1 and 95.0 % for reader 1 and reader 2, respectively. Detection rate of MRA for arteries was 95.0/94.3 %. Most of the undetected arteries were ≤ 1 mm diameter (reader 1: 2 of 3 in CTA and 9 of 16 in MRA; reader 2: 11 of 16 in CTA, and 8 of 18 in MRA). Detection rates for arteries ≥ 2 mm for reader 1/reader 2 were 99.7/98.7 % in CTA and 99.1/97.8 % in MRA, respectively. Detection rates for veins were 99.6/97.4 % in CTA and 97.8/96.9 % in MRA, respectively. Both readers misdiagnosed between 0 and 1 non-present arteries and between 2 and 3 non-present veins in both modalities.
  
  
  CONCLUSIONS
  Modern multislice CT and MRI scanners allow highly accurate evaluation of the vascular anatomy, especially for vessels of ≥ 2 mm diameter. CTA may provide slightly better depiction of very small arteries; however, this may be reader-dependent. Additional factors affecting the choice of imaging modality should include local availability, cost, and the desire to avoid ionizing radiation in healthy transplant donors.
authors.affiliation: Department of Radiology, Charité-Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Engelken
authors.forename: F
authors.initials: F
authors.lastname: Friedersdorff
authors.forename: T F
authors.initials: TF
authors.lastname: Fuller
authors.forename: A
authors.initials: A
authors.lastname: Magheli
authors.forename: K
authors.initials: K
authors.lastname: Budde
authors.forename: F
authors.initials: F
authors.lastname: Halleck
authors.forename: S
authors.initials: S
authors.lastname: Deger
authors.forename: L
authors.initials: L
authors.lastname: Liefeldt
authors.forename: B
authors.initials: B
authors.lastname: Hamm
authors.forename: M
authors.initials: M
authors.lastname: Giessing
authors.forename: G
authors.initials: G
authors.lastname: Diederichs
mesh_terms: D000792:Angiography / Q000379:methods; D001157:Arterial Occlusive Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D003287:Contrast Media / Q000009:adverse effects; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D007668:Kidney / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology; D016030:Kidney Transplantation; D019520:Living Donors; D018810:Magnetic Resonance Angiography; D015588:Observer Variation; D011300:Preoperative Care; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000473:pathology; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media