title: Allergy to IXIARO and BIKEN Japanese encephalitis vaccines.
abstract: We describe an allergic reaction to both mouse brain-derived BIKEN and Vero cell-derived IXIARO Japanese encephalitis (JE) vaccines in a single traveler. In the absence of the stabilizers and murine proteins in the BIKEN vaccine, a common factor in both vaccines is likely to be responsible, possibly JE virus antigen itself.
authors.affiliation: Regional Infectious Diseases Unit, Western General Hospital, Edinburgh, UK. andrew.mccallum@nhslothian.scot.nhs.uk
authors.forename: Andrew D
authors.initials: AD
authors.lastname: McCallum
authors.forename: Michael E
authors.initials: ME
authors.lastname: Jones
mesh_terms: D000368:Aged; D018926:Anti-Allergic Agents / Q000008:administration & dosage*; D000914:Antibodies, Viral / Q000276:immunology; D004672:Encephalitis, Japanese / Q000276:immunology / Q000517:prevention & control; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D022321:Japanese Encephalitis Vaccines / Q000008:administration & dosage / Q000009:adverse effects*; D014195:Travel; D016896:Treatment Outcome; D014581:Urticaria / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology
chemical_list: D018926:Anti-Allergic Agents; D000914:Antibodies, Viral; D022321:Japanese Encephalitis Vaccines