title: Nasal tip cutaneous metastases secondary to lung carcinoma: three case reports and a review of the literature.
abstract: Cutaneous metastatic carcinoma of the nose is a rare presentation associated with lung cancer. We report here 3 cases of cutaneous metastatic carcinoma of the nose that originated from lung cancer. Two men, age 61 and 76 years, with lung cancers were referred for evaluation of a tumour on the tip of the nose. The third patient, a 57-year-old man, had developed a rosacea-like tumour on the tip of the nose; although he had no history of internal cancer, whole-body positron-emission tomography-computed tomography revealed a primary lung cancer. Skin biopsies of all 3 cases showed metastatic squamous cell carcinoma, and all primary lung cancers were squamous cell carcinomas. Only 3 patients are described here, and further reports are needed to substantiate this interesting phenomenon. When an elderly patient presents to dermatology with a tumour on the nose with or without known internal cancer, it is necessary to approach the diagnosis with caution.
authors.affiliation: Department of Dermatology, Chonnam National University Medical School, 5 Hak-Dong, Dong-Gu, Gwangju, Korea.
authors.forename: Seung Min
authors.initials: SM
authors.lastname: Chun
authors.forename: Young Chul
authors.initials: YC
authors.lastname: Kim
authors.forename: Jee-Bum
authors.initials: JB
authors.lastname: Lee
authors.forename: Seong-Jin
authors.initials: SJ
authors.lastname: Kim
authors.forename: Seung-Chul
authors.initials: SC
authors.lastname: Lee
authors.forename: Young Ho
authors.initials: YH
authors.lastname: Won
authors.forename: Sook Jung
authors.initials: SJ
authors.lastname: Yun
mesh_terms: D000368:Aged; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000556:secondary* / Q000628:therapy; D017809:Fatal Outcome; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging / Q000379:methods; D009367:Neoplasm Staging; D009669:Nose Neoplasms / Q000556:secondary* / Q000628:therapy; D049268:Positron-Emission Tomography; D011237:Predictive Value of Tests; D012878:Skin Neoplasms / Q000556:secondary* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D051598:Whole Body Imaging