title: Evaluation of minimum inhibitory and minimum bactericidal concentration of nano-silver base inorganic anti-microbial agent (Novaron(®)) against streptococcus mutans.
abstract: OBJECTIVE
  We attempted to find the possibility of determining the minimum inhibitory concentration and minimum bactericidal concentration needed for nano-silver base inorganic anti-microbial agent (Novaron(®) AG 300, AG 1100) against Streptococcus mutans in vitro using broth dilution assay.
  
  
  METHODS
  An ampoule of freeze-dried S. mutans NCTC reference strain was revived, and the colony-forming units (CFU) were calculated. The MIC and MBC was determined by broth dilution assay using different concentrations of Novaron(®) AG 300 and Novaron(®) AG 1100 against 1 × 10(5) CFU/ml of S. mutans.
  
  
  RESULTS
  The MIC and MBC of Novaron(®) AG 300 and Novaron(®) AG 1100 against S. mutans were found to be 40 μg/ml.
  
  
  CONCLUSIONS
  Novaron(®) has anti-bacterial effect against S. mutans. Further studies are needed to explore the applicability of these silver-supported anti- microbial agents in clinical dentistry.
authors.affiliation: Department of Pedodontics and Preventive Dentistry, Kanti Devi Denta College and Hospital, Mathura, Uttar Pradesh, India.
authors.forename: Goda
authors.initials: G
authors.lastname: Holla
authors.forename: Ramakrishna
authors.initials: R
authors.lastname: Yeluri
authors.forename: Autar Krishen
authors.initials: AK
authors.lastname: Munshi
keywords: Broth dilution assay; MBC; MIC; S. Mutans; novaron®; silver-supported anti-microbial agent