title: Segmental ulcerated perineal hemangioma of infancy: a complex case of PELVIS syndrome successfully treated using a multidisciplinary approach.
abstract: We report a case of PELVIS (perineal hemangioma, external genital malformations, lipomyelomeningocele, vesicorenal abnormalities, imperforate anus and skin tag) syndrome in which hemangioma in the perineal area was misdiagnosed at birth as diaper rash. Investigations revealed associated vesicorenal and spinal abnormalities. We emphasize careful diagnosis of suspicious lesions at birth and confirm the successful use of propranolol in treating ulcerated segmental hemangiomas.
authors.affiliation: Department of Dermatology, School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
authors.forename: Shivani B
authors.initials: SB
authors.lastname: Kaushik
authors.forename: Shawn G
authors.initials: SG
authors.lastname: Kwatra
authors.forename: Thomas W
authors.initials: TW
authors.lastname: McLean
authors.forename: Alexander
authors.initials: A
authors.lastname: Powers
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: Atala
authors.forename: Gil
authors.initials: G
authors.lastname: Yosipovitch
mesh_terms: D000015:Abnormalities, Multiple / Q000628:therapy*; D006391:Hemangioma / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007021:Hypospadias / Q000150:complications; D007223:Infant; D008297:Male; D008591:Meningomyelocele / Q000150:complications; D011433:Propranolol / Q000008:administration & dosage*; D012878:Skin Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D012883:Skin Ulcer / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D013577:Syndrome; D014665:Vasodilator Agents / Q000008:administration & dosage
chemical_list: D014665:Vasodilator Agents; D011433:Propranolol