title: Influence of fresh frozen plasma as a trigger factor for kidney dysfunction in cardiovascular surgery.
abstract: OBJECTIVE
  Kidney dysfunction is a major complication in the postoperative cardiac surgery setting. Operative risk factors for its development are cardiopulmonary bypass, anemia, antifibrinolytic drugs and blood transfusion. The objective of this study was to identify the risk factors for developing kidney dysfunction in patients undergoing cardiac surgery.
  
  
  METHODS
  Ninety-seven patients were studied and 84 were analyzed. The sample was stratified into two groups. A serum creatinine higher than 30% compared to the preoperative period was considered for the kidney dysfunction group (n=9; 10.71%). There also was a control group when the increase in serum creatinine remained lower than 30% (n=75; 89.28%).
  
  
  RESULTS
  It was observed that intraoperative transfusion of fresh frozen plasma in the control group was 2.05 ± 0.78 units and 3.80 ± 2.16 units in the kidney dysfunction group with P= 0.032.
  
  
  CONCLUSIONS
  It was possible to associate that fresh frozen plasma transfusion is a risk factor for postoperative kidney dysfunction after cardiovascular surgery.
authors.affiliation: Graduate Program in Health Sciences, IAMSPE, São Paulo, SP, Brazil.
authors.forename: Valdir Carlos
authors.initials: VC
authors.lastname: Parreiras
authors.forename: Isabella de Sá
authors.initials: Ide S
authors.lastname: Rocha
authors.forename: Antônio Sérgio
authors.initials: AS
authors.lastname: Martins
authors.forename: Enoch Brandão de Souza
authors.initials: EB
authors.lastname: Meira
authors.forename: Fábio Papa
authors.initials: FP
authors.lastname: Taniguchi
mesh_terms: D000368:Aged; D013504:Cardiovascular Surgical Procedures / Q000009:adverse effects*; D016009:Chi-Square Distribution; D003404:Creatinine / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010949:Plasma; D011183:Postoperative Complications / Q000209:etiology; D011184:Postoperative Period; D051437:Renal Insufficiency / Q000097:blood / Q000209:etiology*; D012307:Risk Factors; D018709:Statistics, Nonparametric; D065227:Transfusion Reaction
chemical_list: D003404:Creatinine