title: Water-soluble and pH-responsive polymeric nanotubes from cyclic peptide templates.
abstract: Water-soluble organic nanotubes were prepared by convergently conjugating polymers of hydroxyethyl acrylate (HEA) and acrylic acid (AA) to self-assembling cyclic octapeptides of alternating D and L chirality. The structure of the self-assembled tubes was characterised in a number of polar solvents, and notably water, by using light scattering, TEM and small angle neutron scattering (SANS) techniques. In addition, the self-assembly into tubes could be controlled by exploiting the pH responsiveness of acrylic acid polymers.
authors.affiliation: School of Chemistry (Building F11), The University of Sydney, NSW, 2006, Australia.
authors.forename: Robert
authors.initials: R
authors.lastname: Chapman
authors.forename: Gregory G
authors.initials: GG
authors.lastname: Warr
authors.forename: Sébastien
authors.initials: S
authors.lastname: Perrier
authors.forename: Katrina A
authors.initials: KA
authors.lastname: Jolliffe
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D043942:Nanotubes / Q000737:chemistry*; D010456:Peptides, Cyclic / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D012997:Solvents; D014867:Water / Q000737:chemistry*
chemical_list: D000179:Acrylates; D010456:Peptides, Cyclic; D011108:Polymers; D012997:Solvents; D014867:Water