title: An unusual cluster of Acremonium kiliense fungaemias in a haematopoietic cell transplantation unit.
abstract: The genus Acremonium (formerly known as Cephalosporium) is a large polyphyletic fungal genus that comprises approximately 150 phylogenetically distant species, commonly isolated from the environment. Clinical cases concern mostly superficial infections after traumatic inoculation, but there are reports of opportunistic invasive infections in immunocompromised patients. Acremonium kiliense has been described as a cause of mycetoma, keratitis, endophthalmitis, endocarditis, and continuous ambulatory peritoneal dialysis-associated peritonitis. We describe an unusual cluster of possible catheter-related bloodstream infections due to this pathogen in patients who underwent haematopoietic cell transplantation.
authors.affiliation: First Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Aliki
authors.initials: A
authors.lastname: Ioakimidou
authors.forename: Timoleon-Achilleas
authors.initials: TA
authors.lastname: Vyzantiadis
authors.forename: Ioanna
authors.initials: I
authors.lastname: Sakellari
authors.forename: Michael
authors.initials: M
authors.lastname: Arabatzis
authors.forename: Christos
authors.initials: C
authors.lastname: Smias
authors.forename: Vassiliki
authors.initials: V
authors.lastname: Douka
authors.forename: Aristea
authors.initials: A
authors.lastname: Velegraki
authors.forename: Achilleas
authors.initials: A
authors.lastname: Anagnostopoulos
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Malissiovas
mesh_terms: D000164:Acremonium / Q000187:drug effects / Q000302:isolation & purification* / Q000472:pathogenicity; D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology; D026141:Drug Resistance, Multiple, Fungal; D005260:Female; D016469:Fungemia / Q000188:drug therapy / Q000382:microbiology*; D018380:Hematopoietic Stem Cell Transplantation; D006689:Hodgkin Disease / Q000473:pathology / Q000628:therapy; D006801:Humans; D016867:Immunocompromised Host; D007951:Leukemia, Myeloid / Q000473:pathology / Q000628:therapy; D008297:Male; D008826:Microbial Sensitivity Tests; D009181:Mycoses / Q000097:blood* / Q000188:drug therapy / Q000382:microbiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology / Q000628:therapy; D014184:Transplantation, Homologous; D055815:Young Adult
chemical_list: D000935:Antifungal Agents