title: Importance of histological analysis of seroma fluid.
abstract: The recent observation of anaplastic large cell lymphoma (ALCL) in association with breast implants has initiated a large amount of literature recently, particularly in light of the issues with Poly Implant Prosthese implants. There are now approximately 35-50 reports of this lymphoma associated with breast implants. One of the presenting signs with this lymphoma is a late perimplant seroma. Given Kim et als recommendations for seroma fluid to be analysed, we suggest that all late seromas should be considered for analysis for the possible presence of a causative ALCL pathology, and add to the data currently available on this association.
  
  
  METHODS
  This journal requires that authors  assign a level of evidence to each article. For a full  description of these Evidence-Based Medicine ratings,  please refer to the Table of Contents or the online Instructions to Authors                      http://www.springer.com/00266                                        .
authors.forename: Siun
authors.initials: S
authors.lastname: Murphy
authors.forename: Sean
authors.initials: S
authors.lastname: Carroll
mesh_terms: D001941:Breast Diseases / Q000601:surgery*; D019928:Breast Implantation / Q000009:adverse effects*; D018427:Breast Implants / Q000009:adverse effects*; D005260:Female; D006801:Humans; D049291:Seroma / Q000209:etiology*