title: Learning medical diagnosis models from multiple experts.
abstract: Building classification models from clinical data often requires labeling examples by human experts. However, it is difficult to obtain a perfect set of labels everyone agrees on because medical data are typically very complicated and it is quite common that different experts have different opinions on the same patient data. A solution that has been recently explored by the research community is learning from multiple experts/annotators. The objective of learning from multiple experts is to model different characteristics of the human experts and combine them to obtain a consensus model. In this work, we study and develop a new probabilistic approach for learning classification models from labels provided by multiple experts. Our method explicitly models and incorporates three characteristics of annotators into the learning process: their specific prediction model, consistency and bias. We show that in addition to building a superior classification model, our method also helps to model behavior of annotators. We applied the proposed method to learn different characteristics of Physicians labeling clinical records for Heparin Induced Thrombocytopenia (HIT) and combine them in order to obtain a final classifier.
authors.affiliation: Department of Computer Science, University of Pittsburgh, USA. hamed@cs.pitt.edu
authors.forename: Hamed
authors.initials: H
authors.lastname: Valizadegan
authors.forename: Quang
authors.initials: Q
authors.lastname: Nguyen
authors.forename: Milos
authors.initials: M
authors.lastname: Hauskrecht
mesh_terms: D000465:Algorithms; D000925:Anticoagulants / Q000009:adverse effects; D001185:Artificial Intelligence; D057286:Electronic Health Records / Q000145:classification*; D006493:Heparin / Q000009:adverse effects; D006801:Humans; D055641:Mathematical Concepts; D008962:Models, Theoretical; D011183:Postoperative Complications / Q000175:diagnosis; D013921:Thrombocytopenia / Q000139:chemically induced / Q000175:diagnosis
chemical_list: D000925:Anticoagulants; D006493:Heparin