title: Thiazolidinediones : A class of pharmacologically important molecules.
abstract: Thiazolidinediones are one of the important chemical class of heterocyclic compounds that can be synthesized from thiourea and chloroacetic acid. Thiazolidinedione ring upon substitution with different scaffolds like benzylidene, methoxynapthalene, ester, benzyl shows wide spectrum of pharmacological activities like antihyperglycemic, anticancer, aldose reductase (ALR) inhibition, anti-inflammatory, PGDH inhibition, Keratin pigmentation, antioxidant and antimicrobial activity. Many drugs are marketed as well as removed amongst thiazolidinediones. Present study includes review on synthesis and various pharmacological activities associated with thaizolidinediones.
authors.affiliation: Department of Pharmaceutical Chemistry, Sinhgad Institute Of Pharmacy, Pune (MS) India. sainathaher88@gmail.com.
authors.forename: Sainath B
authors.initials: SB
authors.lastname: Aher
authors.forename: Pratibha B
authors.initials: PB
authors.lastname: Auti
authors.forename: Mandar H
authors.initials: MH
authors.lastname: Washimkar