title: N,N'-bis-[(3-hy-droxy-4(4H)-oxypyran-2-yl)meth-yl]-N,N'-dimethyl-ethylene-1,2-diammonium tetra-chloridoplatinate(II) dihydrate.
abstract: The title compound (C(16)H(22)N(2)O(6))[PtCl(4)]·2H(2)O, shows anti-proliferative activity in eight tumor cell lines. The asymmetric unit consists of one solvent water mol-ecule on a general position, and one half of each of the polyammonium cation and the tetrachloridoplatinate(II) anion, both of them located on centers of inversion. In the crystal, the cations are connected via hydrogen bonding between the carbonyl O atoms and the hydroxyl H atoms into zigzag chains that elongate in the c-axis direction. In addition, the carbonyl O atom is hydrogen-bonded to the water mol-ecule which, in turn, inter-acts with the [PtCl(4)](2-) anion. Finally, the chains are linked by N-H(+)⋯Cl inter-actions into a three-dimensional network.
authors.affiliation: Department of Basic Sciences and Fundamentals, University of Urbino, I-61029 Urbino,  Italy.
authors.forename: Vieri
authors.initials: V
authors.lastname: Fusi
authors.forename: Luca
authors.initials: L
authors.lastname: Giorgi
authors.forename: Eleonora
authors.initials: E
authors.lastname: Macedi
authors.forename: Paola
authors.initials: P
authors.lastname: Paoli
authors.forename: Patrizia
authors.initials: P
authors.lastname: Rossi