title: Aortic valve stenosis: to the gradient and beyond--the mismatch between area and gradient severity.
abstract: The clinical severity of aortic stenosis (AS) is based largely on symptoms. However, AS severity is primarily determined by estimating the aortic valve area (AVA) and pressure gradients (ΔP). Conditions may arise in which there is a mismatch in severity between AVA and ΔP determinations secondary to errors in measurement and/or assumption, alterations of flow, or variations in the magnitude of pressure recovery. The cause of discrepancy between area and gradient determinations must be deciphered so as to best counsel patients on the most ideal treatment strategy.
authors.affiliation: Department of Cardiology, William Beaumont Hospital, Royal Oak, Michigan 48073, USA.
authors.forename: Amr E
authors.initials: AE
authors.lastname: Abbas
authors.forename: Laura M
authors.initials: LM
authors.lastname: Franey
authors.forename: James
authors.initials: J
authors.lastname: Goldstein
authors.forename: Steven
authors.initials: S
authors.lastname: Lester
mesh_terms: D001021:Aortic Valve / Q000503:physiopathology*; D001024:Aortic Valve Stenosis / Q000175:diagnosis* / Q000503:physiopathology; D001783:Blood Flow Velocity / Q000502:physiology*; D006328:Cardiac Catheterization / Q000379:methods*; D015150:Echocardiography, Doppler / Q000379:methods*; D006801:Humans; D012720:Severity of Illness Index