title: Acute cervical dystonia after the first dose of butamirate citrate.
abstract: Butamirate citrate is a central-acting antitussive drug and is widely used in clinical practice in childhood. It is thought that to be centrally active antitussive drugs act through receptors in the brainstem to inhibit cough, and these findings were based on the evidence of animal models. Central nervous system adverse effects of cough suppressants are rare and include irritability, lethargy, hallucinations, and dystonic reactions. In this report, we present the first patient who developed cervical dystonia shortly after the first dose of butamirate citrate, and the patient's symptoms improved immediately after a single intramuscular dosage of biperiden.
authors.affiliation: Division of Pediatric Neurology, Department of Pediatric Neurology, Dokuz Eylul University Medicine Faculty, Izmir, Turkey. dr.erhanbayram@yahoo.com
authors.forename: Erhan
authors.initials: E
authors.lastname: Bayram
authors.forename: Pakize
authors.initials: P
authors.lastname: Karakaya
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Topcu
authors.forename: Uluc
authors.initials: U
authors.lastname: Yis
authors.forename: Semra
authors.initials: S
authors.lastname: Hiz
mesh_terms: D000208:Acute Disease; D000996:Antitussive Agents / Q000009:adverse effects*; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010654:Phenylbutyrates / Q000009:adverse effects*; D014103:Torticollis / Q000139:chemically induced*
chemical_list: D000996:Antitussive Agents; D010654:Phenylbutyrates; C006841:butamirate