title: Hysteroscopic findings in women with menorrhagia.
abstract: OBJECTIVE
  To describe the hysteroscopic findings in patients complaining of menorrhagia to establish any significant association between menorrhagia and benign/malignant intrauterine disorders.
  
  
  METHODS
  Prospective cohort study (Canadian Task Force classification II).
  
  
  METHODS
  University La Sapienza, Rome, Italy.
  
  
  METHODS
  One hundred eighteen premenopausal women undergoing office hysteroscopy for menorrhagia (group A) and 344 premenopausal patients undergoing office hysteroscopy for other indications (noncyclic abnormal uterine bleeding, infertility, ultrasonographic abnormalities, etc) (group B).
  
  
  METHODS
  Office hysteroscopy.
  
  
  RESULTS
  Data on the prevalence of hysteroscopic findings (cervical polyps, endometrial polyps, submucous myomas, low-grade hyperplasia and high-grade hyperplasia/endometrial carcinoma) were compared between group A and group B. The total prevalence, as well as the prevalence of type 0 and type I myomas (totally or >50% intracavitary, respectively), and the mean number per patients with submucous myomas was significantly higher in group A compared with group B (p = .0001, p = .024, and p = .017, respectively). Multivariable logistic regression analysis showed a statistically significant association between age (odds ratio 4.15, 95% confidence interval 1.55-11.1 in the 40- to 49-year age group), presence of submucous myomas (odds ratio 2.76, 95% confidence interval 1.52-5.00), and menorrhagia.
  
  
  CONCLUSIONS
  Menorrhagia seems to be associated with aging, the presence and number of submucous myomas, and with the degree of their intracavitary development.
authors.affiliation: Department of Woman's Health Care, University of Rome La Sapienza - S. Andrea Hospital; Minimally Invasive Surgery Unit, Fabia Mater Clinic, Rome, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: De Angelis
authors.forename: Antonella
authors.initials: A
authors.lastname: Carnevale
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Santoro
authors.forename: Italo
authors.initials: I
authors.lastname: Nofroni
authors.forename: Marialuigia
authors.initials: M
authors.lastname: Spinelli
authors.forename: Maurizio
authors.initials: M
authors.lastname: Guida
authors.forename: Luca
authors.initials: L
authors.lastname: Mencaglia
authors.forename: Attilio
authors.initials: A
authors.lastname: Di Spiezio Sardo
mesh_terms: D000328:Adult; D000367:Age Factors; D002277:Carcinoma / Q000150:complications*; D016001:Confidence Intervals; D004714:Endometrial Hyperplasia / Q000150:complications; D016889:Endometrial Neoplasms / Q000150:complications*; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D007889:Leiomyoma / Q000150:complications*; D008595:Menorrhagia / Q000209:etiology*; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D011127:Polyps / Q000150:complications*; D002577:Uterine Cervical Diseases / Q000150:complications*; D002578:Uterine Cervical Dysplasia / Q000150:complications; D014594:Uterine Neoplasms / Q000150:complications