title: Repurposing the Pap smear: one step closer to gynecologic cancer screening.
abstract: Prevention and early detection remain essential to decreasing cancer mortality. Screening DNA in Pap smears has the potential to increase the rate of early detection of endometrial and ovarian cancers. In this issue of Science Translational Medicine, Kinde and colleagues use advanced sequencing technology to evaluate DNA to screen for gynecologic malignancies.
authors.affiliation: Department of Gynecologic Oncology and Reproductive Medicine, M. D. Anderson Cancer Center, University of Texas, Houston, TX 77030, USA. swestin@mdanderson.org
authors.forename: Shannon N
authors.initials: SN
authors.lastname: Westin
authors.forename: Gordon B
authors.initials: GB
authors.lastname: Mills
authors.forename: Andrea P
authors.initials: AP
authors.lastname: Myers
mesh_terms: D004273:DNA, Neoplasm / Q000032:analysis*; D016889:Endometrial Neoplasms / Q000175:diagnosis*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000175:diagnosis*; D065006:Papanicolaou Test; D014626:Vaginal Smears
chemical_list: D004273:DNA, Neoplasm