title: [Fibrin glue-assisted lamellar keratoplasty for the treatment of corneal ulcer].
abstract: OBJECTIVE
  To investigated the feasibility of fibrin glue-assisted sutureless lamellar keratoplasty (LK) in patients with corneal ulcer.
  
  
  METHODS
  Noncomparative interventional case series. In 21 eyes of 21 patients with terriens marginal degeneration (TMD) or corneal ulcer after trauma, sutureless lamellar keratoplasty (LK) using fibrin glue was performed. Postoperatively, the graft status, graft clarity, the visual prognosis and postoperative complications were recorded.
  
  
  RESULTS
  There were 16 cases suffered with Terriens marginal degeneration (TMD) and 5 cases with corneal ulcer after foreign body removed. All the corneal ulcers were successfully healed after the procedure, the operative complications included corneal perforation during operation in 1 case, recurrence of TMD in 1 case and graft opacity in 2 cases. There was no graft dislocation, hydrops between graft and recipient interface, secondary infection and graft rejection after surgery, 19 cases had improved best-corrected visual acuity (BCVA) while 2 cases had poor vision acuity due to graft opacity (t = -2.587, P = 0.018).
  
  
  CONCLUSIONS
  Fibrin glue-assisted sutureless LK showed excellent graft stability in all patients.
authors.affiliation: Ocular Surface and Corneal Disease Department, Affiliated Xiamen Eye Center of Xiamen University, Xiamen 361001, China.
authors.forename: Hu-ping
authors.initials: HP
authors.lastname: Wu
authors.forename: Nuo
authors.initials: N
authors.lastname: Dong
authors.forename: Su-zhen
authors.initials: SZ
authors.lastname: Xie
authors.forename: Xue-zhi
authors.initials: XZ
authors.lastname: Li
authors.forename: Shen
authors.initials: S
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016039:Corneal Transplantation / Q000379:methods*; D003320:Corneal Ulcer / Q000601:surgery*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D055815:Young Adult
chemical_list: D015718:Fibrin Tissue Adhesive