title: Single Walled Carbon Nanotubes/polypyrrole-GOx composite films to modify gold microelectrodes for glucose biosensors: Study of the extended linearity.
abstract: A glucose biosensor was assembled using gold microelectrodes (diameter of 250 μm) coated by Single-Walled Carbon Nanotubes (SWCNTs), via the Electrophoresis Deposition Process (EPD). This nanostructured platform was successfully used to deposit the poly(pyrrole)/glucose oxidase film (PPy/GOx). The most important result of this biosensors was the wide linear range of concentration, ranging from 4 to100 mM (covering the hypo- and hyper-glycemia range, useful in diabetes). This extended linearity offered the possibility to measure glucose from 0.560 to 12.0 mM, with a detection limit of 50 μM (useful for hypo-glycemia disease).
authors.affiliation: Università Tor Vergata, Dipartimento di Chimica, via della Ricerca Scientifica 1, 00133 Roma, Italy. federica.valentini@uniroma2.it
authors.forename: F
authors.initials: F
authors.lastname: Valentini
authors.forename: L
authors.initials: L
authors.lastname: Galache Fernàndez
authors.forename: E
authors.initials: E
authors.lastname: Tamburri
authors.forename: G
authors.initials: G
authors.lastname: Palleschi
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D003217:Conductometry / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005947:Glucose / Q000032:analysis* / Q000737:chemistry; D005949:Glucose Oxidase / Q000737:chemistry*; D006046:Gold / Q000737:chemistry; D006108:Graphite / Q000737:chemistry; D016014:Linear Models; D008839:Microelectrodes; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D037742:Nanotubes, Carbon; D010087:Oxides; D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole; D006046:Gold; D006108:Graphite; D005949:Glucose Oxidase; D005947:Glucose