title: Bombyx mori silk fibroin scaffolds for bone regeneration studied by bone differentiation experiment.
abstract: Bombyx mori silk fibroin (SF) shows remarkably earlier calcification than bovine serum albumin, indicating advantage of the SF scaffold for bone regeneration. We provide evidence for the first time, that SF not only activate early differentiation markers of osteoblasts, but also activate expression of the late differentiation markers.
authors.affiliation: Department of Biotechnology, Tokyo University of Agriculture and Technology, 2-24-16 Naka-chou, Koganei, Tokyo 184-8588, Japan.
authors.forename: Sayaka
authors.initials: S
authors.lastname: Miyamoto
authors.forename: Ryo
authors.initials: R
authors.lastname: Koyanagi
authors.forename: Yasumoto
authors.initials: Y
authors.lastname: Nakazawa
authors.forename: Aya
authors.initials: A
authors.lastname: Nagano
authors.forename: Yoshimitsu
authors.initials: Y
authors.lastname: Abiko
authors.forename: Masaki
authors.initials: M
authors.lastname: Inada
authors.forename: Chisato
authors.initials: C
authors.lastname: Miyaura
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Asakura
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D012831:Bombyx; D001861:Bone Regeneration; D002113:Calcification, Physiologic; D002454:Cell Differentiation; D002460:Cell Line; D005349:Fibroins; D010006:Osteoblasts / Q000166:cytology* / Q000378:metabolism; D054457:Tissue Scaffolds
chemical_list: D015415:Biomarkers; D005349:Fibroins