title: Diffusion tensor imaging and fiber tractography in brain malformations.
abstract: Diffusion tensor imaging (DTI) is an advanced MR technique that provides qualitative and quantitative information about the micro-architecture of white matter. DTI and its post-processing tool fiber tractography (FT) have been increasingly used in the last decade to investigate the microstructural neuroarchitecture of brain malformations. This article aims to review the use of DTI and FT in the evaluation of a variety of common, well-described brain malformations, in particular by pointing out the additional information that DTI and FT renders compared with conventional MR sequences. In addition, the relevant existing literature is summarized.
authors.affiliation: Division of Pediatric Radiology, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, 600 N. Wolfe St., Nelson Basement, B-173, Baltimore, MD 21287-0842, USA.
authors.forename: Andrea
authors.initials: A
authors.lastname: Poretti
authors.forename: Avner
authors.initials: A
authors.lastname: Meoded
authors.forename: Andrea
authors.initials: A
authors.lastname: Rossi
authors.forename: Charles
authors.initials: C
authors.lastname: Raybaud
authors.forename: Thierry A G M
authors.initials: TA
authors.lastname: Huisman
mesh_terms: D000015:Abnormalities, Multiple; D002526:Cerebellar Diseases / Q000473:pathology; D002531:Cerebellum / Q000002:abnormalities; D056324:Diffusion Tensor Imaging / Q000379:methods*; D005124:Eye Abnormalities / Q000473:pathology; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D021621:Imaging, Three-Dimensional; D052177:Kidney Diseases, Cystic / Q000473:pathology; D009412:Nerve Fibers / Q000473:pathology*; D009421:Nervous System Malformations / Q000473:pathology*; D015835:Ocular Motility Disorders / Q000235:genetics / Q000473:pathology; D012160:Retina / Q000002:abnormalities / Q000473:pathology; D012600:Scoliosis / Q000235:genetics