title: Transient Monoclonal Gammopathy Induced by Disseminated Staphylococcus aureus Infection.
abstract: Monoclonal gammopathy reflects a serological disorder suggesting a plasma cell dyscrasia or a B-cell abnormality. However, it may occasionally be encountered as a transient manifestation in the course of several diseases including infections. This is the first reported case of a transient monoclonal gammopathy IgG lambda light chain associated with a Staphylococcus aureus infection that was complicated with renal abscess and vertebral spondylodiscitis in a previously healthy 68-year-old male. We observed a complete resolution of the gammopathy within three months of medical treatment before the entire restoration of all clinical and laboratory findings. Many invasive and cost-intensive diagnostic procedures had preceded the exclusion of a malignancy. The clinical significance and the exact pathogenesis of transient monoclonality are poorly understood and remain a matter of speculation.
authors.affiliation: 1st Department of Internal Medicine, "Georgios Papanikolaou" General Hospital, Exochi, 570 10 Thessaloniki, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Stoimenis
authors.forename: Christina
authors.initials: C
authors.lastname: Spyridonidou
authors.forename: Nikos
authors.initials: N
authors.lastname: Papaioannou