title: Lung window preparation in mice.
abstract: A thoracic window model has been developed in mice that allows temporal observation of the microcirculation of tumors implanted on the pleural surface without surgical manipulation at the time of observation. Preparation of this lung window model is described here. It allows the study of pleural metastases of various origins as well as primary lung cancer in an orthotopic setting.
authors.forename: Rakesh K
authors.initials: RK
authors.lastname: Jain
authors.forename: Lance L
authors.initials: LL
authors.lastname: Munn
authors.forename: Dai
authors.initials: D
authors.lastname: Fukumura
mesh_terms: D000818:Animals; D051379:Mice; D009362:Neoplasm Metastasis / Q000473:pathology*; D010997:Pleural Neoplasms / Q000473:pathology*; D013903:Thoracic Surgery / Q000379:methods*