title: Impact of obesity on uvulopalatopharyngoplasty success in patients with severe obstructive sleep apnea: a retrospective single-center study in Taiwan.
abstract: CONCLUSIONS
  Our findings suggest that, in Asian patients with severe obstructive sleep apnea (OSA), obesity is a better predictor of uvulopalatopharyngoplasty (UPPP) failure than Friedman stage III.
  
  
  OBJECTIVE
  This study evaluated UPPP success rates in obese and non-obese Asian patients treated for severe OSA.
  
  
  METHODS
  Records of patients who underwent UPPP for treatment of OSA were retrospectively reviewed. Preoperative and postoperative apnea/hypopnea index (AHI) and Epworth Sleepiness Scale (ESS) score, and Friedman stage were compared in non-obese (body mass index (BMI) <27 kg/m(2)) and obese (BMI ≥27 kg/m(2)) patients. Treatment success was defined as >50% reduction in preoperative AHI or postoperative AHI of <20 events/h.
  
  
  RESULTS
  Treatment success was significantly lower (p < 0.0001) in the obese group (24.6%) compared with the non-obese group (62.5%). After adjusting for gender, age, BMI, Friedman stage, and preoperative AHI and ESS score, obesity was a significant independent negative predictor of treatment success (adjusted OR = 0.297, 95% CI = 0.114-0.773, p = 0.013).
authors.affiliation: Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan, ROC.
authors.forename: Dung-Yun
authors.initials: DY
authors.lastname: Shie
authors.forename: Yung-An
authors.initials: YA
authors.lastname: Tsou
authors.forename: Chih-Jaan
authors.initials: CJ
authors.lastname: Tai
authors.forename: Ming-Hsui
authors.initials: MH
authors.lastname: Tsai
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D006970:Disorders of Excessive Somnolence / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D010160:Palate, Soft / Q000601:surgery*; D010614:Pharynx / Q000601:surgery*; D017286:Polysomnography; D011183:Postoperative Complications / Q000175:diagnosis*; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis* / Q000601:surgery*; D013624:Taiwan; D014068:Tonsillectomy / Q000379:methods; D016896:Treatment Outcome; D014609:Uvula / Q000601:surgery*; D055815:Young Adult