title: PXR polymorphisms interacted with CYP2B6 polymorphisms on methadone metabolites.
authors.forename: Hui-Ju
authors.initials: HJ
authors.lastname: Tsai
authors.forename: Sheng-Chang
authors.initials: SC
authors.lastname: Wang
authors.forename: Jia-Ni
authors.initials: JN
authors.lastname: Tian
authors.forename: Tsung-Kai
authors.initials: TK
authors.lastname: Chang
authors.forename: Ing-Kang
authors.initials: IK
authors.lastname: Ho
authors.forename: Chin-Fu
authors.initials: CF
authors.lastname: Hsiao
authors.forename: Chia-Hui
authors.initials: CH
authors.lastname: Chen
authors.forename: Happy Kuy-Lok
authors.initials: HK
authors.lastname: Tan
authors.forename: Linen
authors.initials: L
authors.lastname: Lin
authors.forename: Chi-Shin
authors.initials: CS
authors.lastname: Wu
authors.forename: Lien-Wen
authors.initials: LW
authors.lastname: Su
authors.forename: Chieh-Liang
authors.initials: CL
authors.lastname: Huang
authors.forename: Yi-Hong
authors.initials: YH
authors.lastname: Yang
authors.forename: Ming-Lun
authors.initials: ML
authors.lastname: Liu
authors.forename: Keh-Ming
authors.initials: KM
authors.lastname: Lin
authors.forename: Yu-Li
authors.initials: YL
authors.lastname: Liu
mesh_terms: D000701:Analgesics, Opioid / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics* / Q000378:metabolism; D001711:Biotransformation; D065702:Cytochrome P-450 CYP2B6; D005787:Gene Frequency; D005838:Genotype; D006556:Heroin Dependence / Q000097:blood / Q000534:rehabilitation*; D006801:Humans; D016014:Linear Models; D015810:Linkage Disequilibrium; D008099:Liver / Q000201:enzymology*; D008691:Methadone / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use; D058850:Opiate Substitution Treatment; D010089:Oxidoreductases, N-Demethylating / Q000235:genetics* / Q000378:metabolism; D010597:Pharmacogenetics; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide; D000077297:Pregnane X Receptor; D011987:Receptors, Steroid / Q000235:genetics* / Q000378:metabolism; D013624:Taiwan
chemical_list: D000701:Analgesics, Opioid; D000077297:Pregnane X Receptor; D011987:Receptors, Steroid; D001189:Aryl Hydrocarbon Hydroxylases; C585599:CYP2B6 protein, human; D065702:Cytochrome P-450 CYP2B6; D010089:Oxidoreductases, N-Demethylating; D008691:Methadone