title: "Take it up a NOTCH": novel strategies for cancer therapy.
authors.forename: Stefanie L
authors.initials: SL
authors.lastname: Morgan
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Wyant
authors.forename: Daniela M
authors.initials: DM
authors.lastname: Dinulescu
mesh_terms: D019008:Drug Resistance, Neoplasm / Q000502:physiology*; D005260:Female; D006801:Humans; D014411:Neoplastic Stem Cells / Q000378:metabolism / Q000502:physiology*; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D017671:Platinum Compounds / Q000378:metabolism / Q000627:therapeutic use; D000071656:Receptor, Notch3; D051880:Receptors, Notch / Q000276:immunology / Q000378:metabolism / Q000627:therapeutic use*; D015398:Signal Transduction / Q000502:physiology*
chemical_list: C499374:NOTCH3 protein, human; D017671:Platinum Compounds; D000071656:Receptor, Notch3; D051880:Receptors, Notch
keywords: GSI; Notch; anti-Notch inhibitory antibodies; cancer stem cells; clinical trials; key pathways; ovarian cancer; platinum; side population SP; therapy