title: More effective cell-based therapy through biofilm suppression.
abstract: OBJECTIVE
  To determine if targeted biofilm suppression of a specific wound improves the efficacy of cell-based therapy (CBT).
  
  
  METHODS
  A retrospective study designed to compare a cohort of patients who received CBT in conjunction with biofilm-based wound management with published outcomes from randomised controlled trials in the literature, utilising standard care and CBT. Biofilm-based wound management is the use of multiple simultaneous strategies to suppress wound biofilm, specifically targeting the individual wound's bioburden with agents and methods to suppress the wound biofilm and improve wound-bed preparation.
authors.affiliation: Southwest Regional Wound Care Centre, Texas, USA. randy@randallwolcott.com
authors.forename: R D
authors.initials: RD
authors.lastname: Wolcott
authors.forename: S
authors.initials: S
authors.lastname: Cox
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D018441:Biofilms; D016022:Case-Control Studies; D064987:Cell- and Tissue-Based Therapy / Q000379:methods*; D002908:Chronic Disease; D003094:Collagen / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005782:Gels; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012883:Skin Ulcer / Q000628:therapy*; D017768:Skin, Artificial; D014945:Wound Healing; D014947:Wounds and Injuries / Q000628:therapy*
chemical_list: D000890:Anti-Infective Agents; C117898:Apligraf; D005782:Gels; D003094:Collagen