title: [A case of effective chemoradiotherapy using docetaxel and nedaplatin for recurrent anal canal squamous cell carcinoma].
abstract: 69-year-old woman underwent resection of a tumor diagnosed as squamous cell carcinoma of the anal canal. After 4 years and 5 months, computed tomography(CT)showed abdominal and pelvic lymph node swelling. Chemotherapy consisting of biweekly docetaxel(35mg/m2)+nedaplatin(35mg/m2)achieved a partial response. After 20 cycles of chemotherapy, the patient was treated with radiotherapy because of a pelvic lymph node recurrence. Since then, no recurrence has occurred for 16 months. The adverse event was Grade 2 in leucopenia and neutropenia. This case suggested that chemoradiotherapy consisting of docetaxel +nedaplatin may be effective and safe for treating anal canal squamous cell carcinoma.
authors.affiliation: Dept. of Surgery, Social Insurance Ritsurin Hospital, Japan.
authors.forename: Hijiri
authors.initials: H
authors.lastname: Takeuchi
authors.forename: Shiro
authors.initials: S
authors.lastname: Hori
authors.forename: Takahisa
authors.initials: T
authors.lastname: Fujita
authors.forename: Seiji
authors.initials: S
authors.lastname: Mori
authors.forename: Shunju
authors.initials: S
authors.lastname: Indo
authors.forename: Takashi
authors.initials: T
authors.lastname: Maeba
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001005:Anus Neoplasms / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D059248:Chemoradiotherapy; D000077143:Docetaxel; D005260:Female; D006801:Humans; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D012008:Recurrence; D043823:Taxoids / Q000008:administration & dosage
chemical_list: D009944:Organoplatinum Compounds; D043823:Taxoids; D000077143:Docetaxel; C053989:nedaplatin