title: A patient-reported outcome measure to identify occurrence and distress of post-surgery symptoms of WOMen with vulvAr Neoplasia (WOMAN-PRO) - a cross sectional study.
abstract: OBJECTIVE
  The aim of the study was to describe the (a) symptom experience of women with vulvar intraepithelial neoplasia and vulvar cancer (vulvar neoplasia) during the first week after hospital discharge, and (b) associations between age, type of disease, stage of disease, the extent of surgical treatment and symptom experience.
  
  
  METHODS
  This cross-sectional study was conducted in eight hospitals in Germany and Switzerland (Clinical Trial ID: NCT01300663). Symptom experience after surgical treatment in women with vulvar neoplasia was measured with our newly developed WOMAN-PRO instrument. Outpatients (n=65) rated 31 items. We used descriptive statistics and regression analysis.
  
  
  RESULTS
  The average number of symptoms reported per patient was 20.2 (SD 5.77) with a range of 5 to 31 symptoms. The three most prevalent wound-related symptoms were 'swelling' (n=56), 'drainage' (n=54) and 'pain' (n=52). The three most prevalent difficulties in daily life were 'sitting' (n=63), 'wearing clothes' (n=56) and 'carrying out my daily activities' (n=51). 'Tiredness' (n=62), 'insecurity' (n=54) and 'feeling that my body has changed' (n=50) were the three most prevalent psychosocial symptoms/issues. The most distressing symptoms were 'sitting' (Mean 2.03, SD 0.88), 'open spot (e.g. opening of skin or suture)' (Mean 1.91, SD 0.93), and 'carrying out my daily activities' (Mean 1.86, SD 0.87), which were on average reported as 'quite a bit' distressing. Negative associations were found between psychosocial symptom experience and age.
  
  
  CONCLUSIONS
  WOMAN-PRO data showed a high symptom prevalence and distress, call for a comprehensive symptom assessment, and may allow identification of relevant areas in symptom management.
authors.affiliation: Institute for Applied Nursing Sciences IPW, University of Applied Sciences FHS St. Gallen, Rosenbergstrasse 59, 9001 St. Gallen, Switzerland. beate.senn@fhsg.ch
authors.forename: Beate
authors.initials: B
authors.lastname: Senn
authors.forename: Manuela
authors.initials: M
authors.lastname: Eicher
authors.forename: Michael D
authors.initials: MD
authors.lastname: Mueller
authors.forename: René
authors.initials: R
authors.lastname: Hornung
authors.forename: Daniel
authors.initials: D
authors.lastname: Fink
authors.forename: Kaven
authors.initials: K
authors.lastname: Baessler
authors.forename: Monika
authors.initials: M
authors.lastname: Hampl
authors.forename: Kris
authors.initials: K
authors.lastname: Denhaerynck
authors.forename: Rebecca
authors.initials: R
authors.lastname: Spirig
authors.forename: Sandra
authors.initials: S
authors.lastname: Engberg
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011183:Postoperative Complications / Q000453:epidemiology*; D015995:Prevalence; D012044:Regression Analysis; D014846:Vulvar Neoplasms / Q000523:psychology / Q000601:surgery*