title: [The value of monitoring of qualitative content of onco-antigens in serum in diagnostics of malignant tumors].
abstract: The results of monitoring of qualitative content of 8 onco-antigens (CK, CA-242, CA-19-9, CA-125, REA, AFP, SCC, NSE) in serum of 414 patients are presented. The examination of 62 patients with tumors of different localization was carried our in dynamics before and after treatment. The monitoring of concentration of onco-antigens in serum permitted to apply early diagnostics of malignant process to 9 out of 28 patients with unclear clinical symptomatic. The technique informativeness is demonstrated in pre-clinical diagnostic and prognosis of course of oncological diseases. The possibility of transitory increase of concentration of certain onco-antigens under non-oncologic diseases returning to normal values after application of corresponding pharmaceutical treatment is revealed. The broader implementation of this technique into practice of public health is recommended.
authors.forename: T I
authors.initials: TI
authors.lastname: Bulycheva
authors.forename: L A
authors.initials: LA
authors.lastname: Pustovoĭt
authors.forename: S R
authors.initials: SR
authors.lastname: Karagiulian
authors.forename: È G
authors.initials: ÈG
authors.lastname: Shcherbakova
mesh_terms: D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D016022:Case-Control Studies; D003937:Diagnosis, Differential; D018450:Disease Progression; D006801:Humans; D007124:Immunoenzyme Techniques; D009369:Neoplasms / Q000097:blood* / Q000188:drug therapy / Q000601:surgery; D011237:Predictive Value of Tests; D011379:Prognosis; D000091402:Prohibitins
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; C000717331:PHB2 protein, human; D000091402:Prohibitins