title: [Relationship gene polymorphism adipor1 with cardiovascular risk in patients with nonalcoholic fatty liver disease].
abstract: The aim of the research was to study the link between the polymorphic gene ADIPOR1 and the development of cardiovascular risk in patients with non-alcoholic fatty liver disease (NAFLD). It was found that the carriers of the G allele ADIPOR1 rs 1342387, compared with the carriers of the A allele have a potentially higher degree of cardiovascular risk. NAFLD carriers of the G genotype ADIPOR1 observed proatherogenic lipid profile and a significant increase in the thickness of the intima-media. The results confirm the modulation of genetic factors in the implementation of cardiovascular risk in patients with NAFLD.
authors.affiliation: GI "L.T. Malaya Therapy Institute of the NAMS Ukraine", Kharkov.
authors.forename: O
authors.initials: O
authors.lastname: Kolesnikova
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000209:etiology / Q000235:genetics*; D002784:Cholesterol / Q000097:blood / Q000235:genetics; D005234:Fatty Liver / Q000150:complications* / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D065626:Non-alcoholic Fatty Liver Disease; D011110:Polymorphism, Genetic; D020641:Polymorphism, Single Nucleotide; D054419:Receptors, Adiponectin / Q000235:genetics*; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood / Q000235:genetics; D017539:Tunica Intima / Q000473:pathology
chemical_list: C475418:ADIPOR1 protein, human; D054419:Receptors, Adiponectin; D014280:Triglycerides; D002784:Cholesterol