title: Pregnancy and antiphospholipid syndrome.
abstract: APS causes adverse pregnancy outcome, especially in younger patients with SLE or prior thromboses. LAC is the best predictor of adverse outcome. Prior conclusions on the efficacy of heparin for prevention of poor outcome may be suspect. New therapies are under evaluation in animal models but how to introduce them into the clinic is unclear.
authors.affiliation: Department of Medicine and Obstetrics-Gynecology, Weill-Cornell Medical College, Hospital for Special Surgery New York, NY, USA. LockshinM@HSS.edu
authors.forename: Michael D
authors.initials: MD
authors.lastname: Lockshin
mesh_terms: D000818:Animals; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000276:immunology* / Q000628:therapy; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000276:immunology* / Q000628:therapy; D011256:Pregnancy Outcome; D012307:Risk Factors