title: [Efficacy of Le Fort operation and its impact on patients' quality of life].
abstract: OBJECTIVE
  To evaluate the objective and subjective effects of Le Fort operation and its impact on patients' quality of life before and after operation.
  
  
  METHODS
  A total of 48 patients with pelvic organ prolapse undergoing Le Fort operation from October 2005 to May 2010 were recruited. Their clinical data were retrospectively analyzed and regular follow-ups of pelvic examinations and questionnaires conducted. The questionnaires included pelvic floor distress inventory-short form 20 (PFDI-20) and pelvic floor distress impact questionnaire-short form 7 (PFIQ-7).
  
  
  RESULTS
  Forty patients had complete follow-up data. Their mean follow-up period was 22.3 months (range: 12 - 42). Among them, there were recurrence (n = 1), new-onset stress urinary incontinence symptoms (n = 6) and new-onset colorectal-anal symptoms (n = 2). The postoperative scores of PFDI-20, PFIQ-7, UDI-6 and POPDI-6 decreased markedly (P < 0.05).
  
  
  CONCLUSIONS
  Le Fort operation can significantly improve patients' quality of life and subjective prolapse symptoms and lower urinary tract. However its improvement of colorectal-anal symptoms remains to be defined.
authors.affiliation: Department of Gynecology, Peking University People's Hospital, Beijing 100044, China.
authors.forename: Ya-li
authors.initials: YL
authors.lastname: Miao
authors.forename: Li
authors.initials: L
authors.lastname: Jiang
authors.forename: Min
authors.initials: M
authors.lastname: Xie
authors.forename: Jian-liu
authors.initials: JL
authors.lastname: Wang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008875:Middle Aged; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D011788:Quality of Life; D012189:Retrospective Studies; D016896:Treatment Outcome; D014621:Vagina / Q000601:surgery*