title: Evaluation of alveolar bone grafting in unilateral cleft lip and palate patients using a computer-aided diagnosis system.
abstract: OBJECTIVE
  This study aimed to evaluate the trabecular bone changes after alveolar bone grafting in unilateral cleft lip and palate (UCLP) patients using a computer-aided diagnosis (CAD) system.
  
  
  METHODS
  The occlusal radiographs taken from 50 UCLP patients were surveyed retrospectively. The images were categorized as: 50 images in group 0 (before bone grafting), 33 images in group 1 (one month after bone grafting), 24 images in group 2 (2-4 months after bone grafting), 15 images in group 3 (5-7 months after bone grafting), and 21 images in group 4 (8 or more months after bone grafting). Each image was grouped as either "non-cleft side" or "cleft side". The CAD system was used five times for each side to calculate the pixel area based on the mathematical morphology. Significant differences were found using a Wilcoxon signed ranks test or paired samples t test.
  
  
  RESULTS
  The pixel area showed a significant difference between the "non-cleft side" and "cleft side" in group 0 (404.27±103.72/117.73±92.25; p=0.00), group 1 (434.29±86.70/388.31±109.51; p=0.01), and group 4 (430.98±98.11/366.71±154.59; p=0.02). No significant differences were found in group 2 (423.57±98.12/383.47±135.88; p=0.06) or group 3 (433.02±116.07/384.16±146.55; p=0.19).
  
  
  CONCLUSIONS
  Based on the design of this study, alveolar bone grafting was similar to normal bone within 2-7 months postoperatively.
authors.affiliation: Department of Oral Diagnosis, Khon Kaen University, Khon Kaen, Thailand.
authors.forename: Pipop
authors.initials: P
authors.lastname: Sutthiprapaporn
authors.forename: Keiji
authors.initials: K
authors.lastname: Tanimoto
authors.forename: Takashi
authors.initials: T
authors.lastname: Nakamoto
authors.forename: Supaporn
authors.initials: S
authors.lastname: Kongsomboon
authors.forename: Saowaluck
authors.initials: S
authors.lastname: Limmonthol
authors.forename: Poonsak
authors.initials: P
authors.lastname: Pisek
authors.forename: Chutimaporn
authors.initials: C
authors.lastname: Keinprasit
keywords: Diagnosis, Computer-Assisted; Grafting, Bone; Radiography, Dental