title: The era of big trials is over.
authors.affiliation: Division of Oncology, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA.
authors.forename: Melissa
authors.initials: M
authors.lastname: Rooney
authors.forename: Ramaswamy
authors.initials: R
authors.lastname: Govindan
mesh_terms: D002986:Clinical Trials as Topic; D019008:Drug Resistance, Neoplasm / Q000235:genetics*; D023281:Genomics; D006801:Humans; D009369:Neoplasms / Q000235:genetics* / Q000628:therapy