title: [The contribution of Goldstein and Brown to the study of cholesterol metabolism].
abstract: In December 1985, the Nobel Prize of Medicine was awarded to Drs. Joseph L. Goldstein and Michael S. Brown for their fundamental scientific work on the regulation of cholesterol metabolism mediated by the low density lipoprotein receptor pathway. This article briefly reviews the academic and research accomplishments of Drs. Brown and Goldstein as a tribute to these physician-scientists for their well-deserved award and enormous contribution to biomedical science worldwide.
authors.affiliation: Escuela de Medicina, Departamentos de Nutrición, Diabetes y Metabolismo, Pontificia Universidad Católica, Santiago, Chile.
authors.forename: Víctor
authors.initials: V
authors.lastname: Cortés
authors.forename: Tatiana
authors.initials: T
authors.lastname: Vásquez
authors.forename: Antonio
authors.initials: A
authors.lastname: Arteaga
authors.forename: Flavio
authors.initials: F
authors.lastname: Nervi
authors.forename: Attilio
authors.initials: A
authors.lastname: Rigotti
mesh_terms: D002784:Cholesterol / Q000266:history / Q000378:metabolism*; D049673:History, 20th Century; D009613:Nobel Prize
chemical_list: D002784:Cholesterol