title: Preparation and evaluation of bicomponent and homogeneous polyester silk small diameter arterial prostheses.
abstract: The development of a small diameter (≤5 mm) arterial prosthesis requires the appropriate selection of materials, structure and fabrication method so as to provide adequate mechanical properties, superior biocompatibility and precise control over the diameter. In this study, 100% polyester, 100% silk fibroin and a combination of both yarns were woven into seamless tubular prototype prostheses with different basic weaves. After degumming/scouring they met a target inner diameter of 3.9±0.3 mm which demonstrates that weaving is a precise way to manufacture small caliber arterial prostheses. In conclusion, the bicomponent polyester/silk woven samples had superior mechanical properties and improved cytocompatibility compared to commercial ePTFE devices.
authors.affiliation: 1Key Lab of Textile Science and Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai, China.
authors.forename: Xiaoyuan
authors.initials: X
authors.lastname: Yang
authors.forename: Lu
authors.initials: L
authors.lastname: Wang
authors.forename: Guoping
authors.initials: G
authors.lastname: Guan
authors.forename: Martin W
authors.initials: MW
authors.lastname: King
authors.forename: Yuling
authors.initials: Y
authors.lastname: Li
authors.forename: Lei
authors.initials: L
authors.lastname: Peng
authors.forename: Ying
authors.initials: Y
authors.lastname: Guan
authors.forename: Xingyou
authors.initials: X
authors.lastname: Hu
mesh_terms: D001158:Arteries; D001672:Biocompatible Materials; D001807:Blood Vessel Prosthesis; D003187:Compliance; D008422:Materials Testing; D010539:Permeability; D011091:Polyesters; D047011:Silk; D014867:Water
chemical_list: D001672:Biocompatible Materials; D011091:Polyesters; D047011:Silk; D014867:Water
keywords: Arterial prosthesis; cytocompatibility; mechanical properties; poly(ethylene terephthalate); silk; small diameter