title: Clinical outcomes of magnesium-incorporated oxidised implants: a randomised double-blind clinical trial.
abstract: OBJECTIVE
  This study evaluated implant stability and clinical outcomes obtained with magnesium-incorporated oxidised implants (Mg titanate) and compared them to those blasted magnesium-incorporated oxidised implants (blasted Mg titanate).
  
  
  METHODS
  Mg titanate was manufactured using the microarc oxidation (MAO) process. To obtain blasted Mg titanate, the MAO process was performed after blasting with TiO₂ particles. The 15-month, randomised, double -blind clinical trial was conducted on 54 implants in 40 patients (Mg titanate, 27 implants in 18 subjects; blasted Mg titanate, 27 implants in 22 subjects), in whom 4.0 mm × 10 mm implants were placed to restore the unilateral loss of one or two molars in the mandible. The final prosthesis was attached 3 months postoperatively. Implant stability was measured by the implant stability quotient (ISQ) and periotest value (PTV) at the time of implant insertion, and 2, 3, and 15 months postoperatively. Marginal bone loss was evaluated at 2, 6, and 15 months postoperatively. Soft tissue analysis was performed at 15 months postoperatively.
  
  
  RESULTS
  Both implant systems showed high stability at all time points (>71). Mean marginal bone loss was 0.71 ± 0.65 mm and 0.75 ± 0.73 after 15 months in Mg titanate and blasted Mg titanate, respectively. There were no significant differences between the two implant surfaces with respect to ISQ(P = 0.988), PTV(P = 0.935), and marginal bone loss(P = 0.807) after 15 months.
  
  
  CONCLUSIONS
  The success rate after 1 year of follow-up was 100% for both magnesium-incorporated oxidised implants. There were no significant differences in the clinical outcomes between the two surfaces at 15 months follow-up.
authors.affiliation: Department of Dentistry, Oral and Maxillofacial Surgery, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Kang-Mi
authors.initials: KM
authors.lastname: Pang
authors.forename: Jung-Woo
authors.initials: JW
authors.lastname: Lee
authors.forename: Jin-Yong
authors.initials: JY
authors.lastname: Lee
authors.forename: Jai-Bong
authors.initials: JB
authors.lastname: Lee
authors.forename: Soung-Min
authors.initials: SM
authors.lastname: Kim
authors.forename: Myung-Jin
authors.initials: MJ
authors.lastname: Kim
authors.forename: Jong-Ho
authors.initials: JH
authors.lastname: Lee
mesh_terms: D000328:Adult; D016301:Alveolar Bone Loss / Q000209:etiology; D003758:Dental Implantation, Endosseous / Q000379:methods*; D015921:Dental Implants; D017267:Dental Prosthesis Design; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008274:Magnesium / Q000737:chemistry*; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D010084:Oxidation-Reduction; D011446:Prospective Studies; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants; D014025:Titanium; D008274:Magnesium
keywords: bone-implant interactions; clinical research; clinical trials; surface chemistry