title: Registration of 3D fetal brain US and MRI.
abstract: We propose a novel method for registration of 3D fetal brain ultrasound and a reconstructed magnetic resonance fetal brain volumes. The reconstructed MR volume is first segmented using a probabilistic atlas and an ultrasound-like image volume is simulated from the segmentation of the MR image. This ultrasound-like image volume is then affinely aligned with real ultrasound volumes of 27 fetal brains using a robust block-matching approach which can deal with intensity artefacts and missing features in ultrasound images. We show that this approach results in good overlap of four small structures. The average of the co-aligned US images shows good correlation with anatomy of the fetal brain as seen in the MR reconstruction.
authors.affiliation: Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, UK.
authors.forename: Maria
authors.initials: M
authors.lastname: Kuklisova-Murgasova
authors.forename: Amalia
authors.initials: A
authors.lastname: Cifor
authors.forename: Raffaele
authors.initials: R
authors.lastname: Napolitano
authors.forename: Aris
authors.initials: A
authors.lastname: Papageorghiou
authors.forename: Gerardine
authors.initials: G
authors.lastname: Quaghebeur
authors.forename: J Alison
authors.initials: JA
authors.lastname: Noble
authors.forename: Julia A
authors.initials: JA
authors.lastname: Schnabel
mesh_terms: D000465:Algorithms; D001921:Brain / Q000033:anatomy & histology* / Q000196:embryology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique; D016216:Ultrasonography, Prenatal / Q000379:methods*