title: Reduction of trial-to-trial variability in functional near-infrared spectroscopy signals by accounting for resting-state functional connectivity.
abstract: The reduction of trial-to-trial variability (TTV) in task-evoked functional near-infrared spectroscopy signals by considering the correlated low-frequency spontaneous fluctuations that account for the resting-state functional connectivity in the brain is investigated. A resting-state session followed by a task-state session of a right hand finger-tapping task has been performed on five subjects. Significant ipsilateral and bilateral resting-state functional connectivity has been detected at the subjects' motor cortex using the seed correlation method. The correlation coefficients obtained during the resting-state are used to reduce the TTV in the signals measured during the task sessions. The results suggest that correlated spontaneous low-frequency fluctuations contribute significantly to the TTV in the task evoked fNIRS signals.
authors.affiliation: Pusan National University, Department of Cogno-Mechatronics Engineering, 30 Jangjeon-dong, Gumjeong-gu, Busan 609-735, Republic of Korea.
authors.forename: Xiao-Su
authors.initials: XS
authors.lastname: Hu
authors.forename: Keum-Shik
authors.initials: KS
authors.lastname: Hong
authors.forename: Shuzhi Sam
authors.initials: SS
authors.lastname: Ge
mesh_terms: D000328:Adult; D001921:Brain / Q000098:blood supply / Q000378:metabolism / Q000502:physiology; D001931:Brain Mapping / Q000379:methods*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D010100:Oxygen / Q000097:blood; D010108:Oxyhemoglobins / Q000032:analysis; D012815:Signal Processing, Computer-Assisted; D019265:Spectroscopy, Near-Infrared / Q000379:methods*; D013647:Task Performance and Analysis
chemical_list: D006454:Hemoglobins; D010108:Oxyhemoglobins; C100003:deoxyhemoglobin; D010100:Oxygen