title: One-pot cross double-Mannich reaction of acetaldehyde catalyzed by a binaphthyl-based amino sulfonamide.
abstract: A one-pot cross double-Mannich reaction of acetaldehyde was developed, and densely functionalized 1,3-diamines were obtained as a single stereoisomer by use of axially chiral amino sulfonamide (S)-1 as catalyst. Using this catalyst, the one-pot Mannich reaction-aminoxylation was also realized.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.
authors.forename: Taichi
authors.initials: T
authors.lastname: Kano
authors.forename: Ryu
authors.initials: R
authors.lastname: Sakamoto
authors.forename: Yukako
authors.initials: Y
authors.lastname: Yamaguchi
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Itoh
authors.forename: Keiji
authors.initials: K
authors.lastname: Maruoka