title: Oral vaccination of backyard pigs against classical swine fever.
abstract: Vaccination represents a key pillar of most classical swine fever (CSF) control programmes. In backyard production systems the systematic implementation of parenteral vaccination proves to be difficult and alternative delivery mechanisms might be needed. In this study the use of oral vaccination against CSF in backyard pigs was tested under field conditions. The main objective was to assess uptake efficacy and immune response after oral vaccination of backyard pigs with bait vaccine currently used in the European Union for CSF control in wild boar (RIEMSER(®) Schweinepestoralvakzine). In total 85 backyard pigs belonging to 16 holdings were vaccinated orally by distributing four baits per pig, given on two consecutive days. The baits were distributed on pen floors. 73% of the pigs older than 12 weeks (n=41) had protective antibody titres 28 days after oral vaccination. The seroconversion rate in young piglets (n=44, younger than 12 weeks) was 64%. Based on the results obtained we concluded that in an endemic situation where usual control measures (stamping out, zoning with restrictive measures, parenteral vaccination, etc.) may prove to be insufficient, a systematic vaccination based on the use of oral vaccine can be an appropriate tool for an improved CSF control in backyard production systems.
authors.affiliation: Institute of Veterinary Medicine of Serbia, Vojvode Totze 14, 1000 Belgrade, Serbia.
authors.forename: Vesna
authors.initials: V
authors.lastname: Milicevic
authors.forename: Klaas
authors.initials: K
authors.lastname: Dietze
authors.forename: Budimir
authors.initials: B
authors.lastname: Plavsic
authors.forename: Mario
authors.initials: M
authors.lastname: Tikvicki
authors.forename: Julio
authors.initials: J
authors.lastname: Pinto
authors.forename: Klaus
authors.initials: K
authors.lastname: Depner
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D006691:Classical Swine Fever / Q000276:immunology*; D006692:Classical Swine Fever Virus / Q000276:immunology*; D005260:Female; D013552:Swine; D014611:Vaccination / Q000662:veterinary*; D014765:Viral Vaccines / Q000008:administration & dosage* / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines