title: Rapidly fatal multiorgan Langerhans cell histiocytosis in a neonate.
abstract: Multiorgan Langerhans cell histiocytosis (LCH) presenting in the neonatal period is associated with a poor prognosis. We report a 5-day-old neonate who presented at birth with diffuse cutaneous nodules and respiratory failure who received a postmortem diagnosis of LCH. We emphasize the importance of recognizing the cutaneous findings of this rare disease.
authors.affiliation: Harvard Combined Program in Dermatology, Boston, Massachusetts.
authors.forename: Sarah N
authors.initials: SN
authors.lastname: Gee
authors.forename: Jennifer T
authors.initials: JT
authors.lastname: Huang
authors.forename: Birgitta A
authors.initials: BA
authors.lastname: Schmidt
authors.forename: Stephen E
authors.initials: SE
authors.lastname: Gellis
mesh_terms: D017809:Fatal Outcome; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011379:Prognosis; D011693:Purpura / Q000175:diagnosis* / Q000473:pathology; D012131:Respiratory Insufficiency / Q000175:diagnosis*; D012871:Skin Diseases / Q000175:diagnosis* / Q000473:pathology