title: Three-year review of bacteriological profile and antibiogram of burn wound isolates in Van, Turkey.
abstract: The risk of infection in burns is well-known. In recent decades, the antimicrobial resistance of bacteria isolated from burn patients has increased. For this reason, a retrospective study was conducted at Van Training and Research Hospital to analyze the bacterial isolates from the wounds of patients admitted to the Burn Unit and to determine the susceptibility patterns of the commonly cultured organisms over a 3-year period, January 2009 to December 2011.A total of 250 microorganisms were isolated from burn wounds of 179 patients. Our results revealed that the most frequent isolate was Acinetobacter baumannii (23.6%), Pseudomonas aeruginosa (12%), Staphylococcus aureus (11.2%), Escherichia coli (10%) respectively. Multidrug-resistance has emerged as an important concern in our burn unit. Tigecycline, and colistin were found to be the most active drugs against Acinetobacter baumannii. Carbapenems and amikacin, were found to be the most active drugs against other gram negative bacteria. Vancomycin and linezolid were active against gram positive bacteria.Aggressive infection control measures should be applied to limit the emergence and spread of multidrug-resistant pathogens.
authors.affiliation: Microbiology Laboratory, Van Training And Research Hospital, Van, Turkey.
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Bayram
authors.forename: Mehmet
authors.initials: M
authors.lastname: Parlak
authors.forename: Cenk
authors.initials: C
authors.lastname: Aypak
authors.forename: Irfan
authors.initials: I
authors.lastname: Bayram
mesh_terms: D000328:Adult; D000583:Amikacin / Q000008:administration & dosage; D002056:Burns / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D015780:Carbapenems / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000302:isolation & purification; D006801:Humans; D007239:Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D008297:Male; D012189:Retrospective Studies; D014421:Turkey
chemical_list: D015780:Carbapenems; D000583:Amikacin
keywords: antibiotic; burns; resistance; wounds.