title: Movement disorders in 2012: Advancing research towards novel therapeutic approaches.
abstract: Research in movement disorders in 2012 has improved our understanding of the pathogenic mechanisms of disease and led to development of potential novel therapeutic approaches. Key advances were linked to mechanisms underlying spread of neurodegenerative pathology, immunotherapy, stem cells, genetics and deep brain stimulation in parkinsonism and related disorders.
authors.affiliation: Center for Movement Disorders and Neurorestoration, Department of Neurology, University of Florida, College of Medicine, Gainesville, FL 32610, USA.
authors.forename: Nikolaus R
authors.initials: NR
authors.lastname: McFarland
authors.forename: Michael S
authors.initials: MS
authors.lastname: Okun
mesh_terms: D000818:Animals; D046690:Deep Brain Stimulation; D006801:Humans; D007167:Immunotherapy; D051379:Mice; D008822:Mice, Transgenic; D009069:Movement Disorders / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D019636:Neurodegenerative Diseases / Q000235:genetics / Q000473:pathology; D059906:Neuroimaging; D020734:Parkinsonian Disorders / Q000473:pathology / Q000628:therapy; D039904:Pluripotent Stem Cells; D033581:Stem Cell Transplantation; D051844:alpha-Synuclein / Q000502:physiology
chemical_list: D051844:alpha-Synuclein