title: The effects of hydrocephalus on the periventricular white matter in intracerebral hemorrhage: a diffuser tensor imaging study.
abstract: OBJECTIVE
  Many diffusion tensor imaging (DTI) studies have described the effects of hydrocephalus on periventricular white matter in patients with normal pressure hydrocephalus. However, little is known about hydrocephalus following stroke. We investigated the effect of hydrocephalus on periventricular white matter in patients with hydrocephalus after an intracerebral hemorrhage (ICH) using DTI.
  
  
  METHODS
  Fourteen patients with ICH and hydrocephalus, and 17 age- and sex-matched normal control subjects were recruited. DTI parameters were estimated in six regions of interest (ROIs) in periventricular white matter: the anterior corona radiata, the posterior corona radiata, the genu of the corpus callosum, the splenium of corpus callosum, the anterior limb of the internal capsule, and the posterior limb of the internal capsule.
  
  
  RESULTS
  Mean fractional anisotropy of the anterior corona radiata in patients was significantly higher than in controls (p < 0.05), but apparent diffusion coefficient (ADC) was not different in the two groups (p > 0.05). No significant differences between fractional anisotropies and ADCs were observed in the other five ROIs (p > 0.05).
  
  
  CONCLUSIONS
  The anterior corona radiata was found to be more compressed by hydrocephalus than the other five regions of periventricular white matter examined in patients with hydrocephalus following ICH. It is believed that the results of the present study will be useful for the diagnosis and management of hydrocephalus following stroke.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Yeungnam University, Taegu, Republic of Korea.
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Jang
authors.forename: Byung Yeon
authors.initials: BY
authors.lastname: Choi
authors.forename: Chul Hoon
authors.initials: CH
authors.lastname: Chang
authors.forename: Young-Jin
authors.initials: YJ
authors.lastname: Jung
authors.forename: Woo Mok
authors.initials: WM
authors.lastname: Byun
authors.forename: Seong Ho
authors.initials: SH
authors.lastname: Kim
authors.forename: Sang Seok
authors.initials: SS
authors.lastname: Yeo
mesh_terms: D000328:Adult; D000368:Aged; D016880:Anisotropy; D016022:Case-Control Studies; D002543:Cerebral Hemorrhage / Q000150:complications / Q000473:pathology*; D002552:Cerebral Ventricles / Q000473:pathology; D003337:Corpus Callosum / Q000473:pathology*; D056324:Diffusion Tensor Imaging; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000473:pathology*; D020772:Internal Capsule / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009413:Nerve Fibers, Myelinated / Q000473:pathology*; D009434:Neural Pathways / Q000473:pathology; D059906:Neuroimaging