title: [Mediating effects on depression regarding the relationship between negative life events and suicide ideation among college students].
abstract: OBJECTIVE
  To understand the relationship between negative life events and suicide ideation, and how it was influenced by the mediating effect of depression.
  
  
  METHODS
  1145 college students from one university were selected using cluster sampling. Both Symptom Check List (SCL-90) and Questionnaire were administered to measure depression and suicide ideation in the past week and on the prevalence of negative life events and related information. Recent negative life events would include physical illness, academic problem, financial problem and interpersonal conflict etc. Multiple logistic regressions were used to identify the mediating effect of depression.
  
  
  RESULTS
  Physical illness (OR = 2.5, P = 0.028), interpersonal conflict (OR = 7.2, P = 0.002) and financial problem (OR = 1.6, P = 0.026) were significantly associated with suicide ideation, but academically-related problems did not seem to be significantly associated with suicide ideation (OR = 1.8, P = 0.090). After adjusted for depression, both physical illness and interpersonal conflicts were not but financial problem remained significantly associated with suicide ideation (OR = 1.7, P = 0.014). Our data showed that depression fully mediated the relationship between physical illness, interpersonal conflict and suicide ideation, but did not mediate the relationship between financial problem and suicide ideation.
  
  
  CONCLUSIONS
  Depression played different mediating roles between different negative life events and suicide ideation. The findings from this study might be able to provide some clues for the prevention interventions on college students.
authors.affiliation: Department of Maternal and Child Health, Huazhong University of Science and Technology, Wuhan, China.
authors.forename: Jiao
authors.initials: J
authors.lastname: Wu
authors.forename: Yun-tao
authors.initials: YT
authors.lastname: Wu
authors.forename: Shu-xiu
authors.initials: SX
authors.lastname: Feng
authors.forename: Heng
authors.initials: H
authors.lastname: Meng
authors.forename: Hui
authors.initials: H
authors.lastname: Chen
mesh_terms: D000328:Adult; D003863:Depression / Q000453:epidemiology* / Q000523:psychology*; D005260:Female; D006801:Humans; D008016:Life Change Events; D008297:Male; D012307:Risk Factors; D013334:Students / Q000523:psychology*; D059020:Suicidal Ideation; D013406:Suicide, Attempted / Q000706:statistics & numerical data; D011795:Surveys and Questionnaires; D014495:Universities