title: Endoscopic radiofrequency ablation of Barrett's esophagus.
abstract: Recently, extensive data have been published about the safety and efficacy of endoscopic radiofrequency ablation (RFA) of Barrett's esophagus (BE) with early cancer and dysplasia as well as without dysplasia. RFA has been shown to be effective and safe. Circumferential RFA is delivered using the HALO(360+) Ablation System (Covidien, Inc., Mansfield, MA), which consists ofa high-power energy generator, a sizing balloon catheter, and a number of balloon-based ablation catheters with varying outer diameters. Focal RF energy is delivered using the HALO(90) or HALO(60) Ablation Systems (Covidien, Inc., Mansfield, MA), consisting of a radiofrequency energy generator and an endoscope-mounted electrode. Both RFA systems have official approval to be used in the United States, Europe, and other countries for the treatment of BE as well as in patients with gastric antral vascular ectasia and radiation proctopathy. With increasing widespread use of these systems, a full mastery of the equipment and therapeutic technique is essential to maximize eradication rates of BE while maintaining patient safety. A cost-effective patient selection and eradication protocol for RFA is essential to success with this technique in patients with BE. This article will discuss our experience with RFA treatment of BE using the HALO system for effective eradication of Barrett's dysplasia and early Barrett's cancer and review available data especially from the U.S. National Registry.
authors.affiliation: University of Texas Medical School, Houston, TX, USA.
authors.forename: David S
authors.initials: DS
authors.lastname: Wolf
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Dunkin
authors.forename: Atilla
authors.initials: A
authors.lastname: Ertan
mesh_terms: D001471:Barrett Esophagus / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery*; D017115:Catheter Ablation / Q000295:instrumentation* / Q000706:statistics & numerical data*; D004867:Equipment Design; D004945:Esophagoscopy / Q000295:instrumentation* / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D012042:Registries; D018570:Risk Assessment; D025321:Surgery, Computer-Assisted / Q000295:instrumentation / Q000706:statistics & numerical data; D016896:Treatment Outcome