title: [Literature metrology analysis of adverse reactions reports of Denzhanxixin injection].
abstract: OBJECTIVE
  To investigate the effect of Dengzhanxixin injection induced adverse reactions of the general rule and characteristic, guide clinical rational drug use.
  
  
  METHODS
  Through the retrieval of 1979-2012 reported in domestic medical journals of Dengzhanxixin injection induced adverse reactions and case, literature metrology analysis analysis.
  
  
  RESULTS
  The search to Dengzhanxixin injection in 25 cases of adverse drug reactions, the adverse reactions closely related with gender, age, solvent, dose, the combination drugs. The main clinical manifestations of allergic reactions, severe cases can cause allergic shock and multiple organ dysfunction.
  
  
  CONCLUSIONS
  Clinicians and pharmacists should understand of Dengzhanxixin injection pattern and characteristics of adverse reactions, rational drug use norms, strengthen the application of monitoring, reduce the occurrence of adverse reactions.
authors.affiliation: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. chibjyy@163.com
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Li
authors.forename: Yan-Ming
authors.initials: YM
authors.lastname: Xie
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016903:Drug Monitoring; D064420:Drug-Related Side Effects and Adverse Reactions; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000453:epidemiology / Q000209:etiology; D055815:Young Adult
chemical_list: D004365:Drugs, Chinese Herbal