title: Iridium-catalyzed hydrosilylative reduction of glucose to hexane(s).
abstract: In light of diminishing petroleum feedstocks, there is significant interest in developing carbohydrate defunctionalization reactions. In this context we have examined the use of iridium pincer catalysts for the hydrosilylative reduction of sugars, and we report herein complete reduction of silyl-protected glucose to a mixture of hexane isomers.
authors.affiliation: Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, USA.
authors.forename: Matthew P
authors.initials: MP
authors.lastname: McLaughlin
authors.forename: Laura L
authors.initials: LL
authors.lastname: Adduci
authors.forename: Jennifer J
authors.initials: JJ
authors.lastname: Becker
authors.forename: Michel R
authors.initials: MR
authors.lastname: Gagné
mesh_terms: D002384:Catalysis; D005947:Glucose / Q000737:chemistry*; D006586:Hexanes / Q000138:chemical synthesis* / Q000737:chemistry; D007495:Iridium / Q000737:chemistry*; D015394:Molecular Structure; D012821:Silanes / Q000737:chemistry*
chemical_list: D006586:Hexanes; D012821:Silanes; D007495:Iridium; D005947:Glucose