title: A genome-wide association study of depressive symptoms.
abstract: BACKGROUND
  Depression is a heritable trait that exists on a continuum of varying severity and duration. Yet, the search for genetic variants associated with depression has had few successes. We exploit the entire continuum of depression to find common variants for depressive symptoms.
  
  
  METHODS
  In this genome-wide association study, we combined the results of 17 population-based studies assessing depressive symptoms with the Center for Epidemiological Studies Depression Scale. Replication of the independent top hits (p<1×10(-5)) was performed in five studies assessing depressive symptoms with other instruments. In addition, we performed a combined meta-analysis of all 22 discovery and replication studies.
  
  
  RESULTS
  The discovery sample comprised 34,549 individuals (mean age of 66.5) and no loci reached genome-wide significance (lowest p = 1.05×10(-7)). Seven independent single nucleotide polymorphisms were considered for replication. In the replication set (n = 16,709), we found suggestive association of one single nucleotide polymorphism with depressive symptoms (rs161645, 5q21, p = 9.19×10(-3)). This 5q21 region reached genome-wide significance (p = 4.78×10(-8)) in the overall meta-analysis combining discovery and replication studies (n = 51,258).
  
  
  CONCLUSIONS
  The results suggest that only a large sample comprising more than 50,000 subjects may be sufficiently powered to detect genes for depressive symptoms.
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Karin
authors.initials: K
authors.lastname: Hek
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Ayse
authors.initials: A
authors.lastname: Demirkan
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Jari
authors.initials: J
authors.lastname: Lahti
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Antonio
authors.initials: A
authors.lastname: Terracciano
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Alexander
authors.initials: A
authors.lastname: Teumer
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Marilyn C
authors.initials: MC
authors.lastname: Cornelis
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Najaf
authors.initials: N
authors.lastname: Amin
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Erin
authors.initials: E
authors.lastname: Bakshis
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Jens
authors.initials: J
authors.lastname: Baumert
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Jingzhong
authors.initials: J
authors.lastname: Ding
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Yongmei
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Kristin
authors.initials: K
authors.lastname: Marciante
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Osorio
authors.initials: O
authors.lastname: Meirelles
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Nalls
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Yan V
authors.initials: YV
authors.lastname: Sun
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Nicole
authors.initials: N
authors.lastname: Vogelzangs
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Lei
authors.initials: L
authors.lastname: Yu
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Stefania
authors.initials: S
authors.lastname: Bandinelli
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Emelia J
authors.initials: EJ
authors.lastname: Benjamin
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: David A
authors.initials: DA
authors.lastname: Bennett
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Dorret
authors.initials: D
authors.lastname: Boomsma
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Cannas
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Laura H
authors.initials: LH
authors.lastname: Coker
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Eco
authors.initials: E
authors.lastname: de Geus
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Philip L
authors.initials: PL
authors.lastname: De Jager
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Ana V
authors.initials: AV
authors.lastname: Diez-Roux
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Shaun
authors.initials: S
authors.lastname: Purcell
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Frank B
authors.initials: FB
authors.lastname: Hu
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Eric B
authors.initials: EB
authors.lastname: Rimma
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: David J
authors.initials: DJ
authors.lastname: Hunter
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Majken K
authors.initials: MK
authors.lastname: Jensen
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Gary
authors.initials: G
authors.lastname: Curhan
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Kenneth
authors.initials: K
authors.lastname: Rice
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Alan D
authors.initials: AD
authors.lastname: Penman
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Jerome I
authors.initials: JI
authors.lastname: Rotter
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Nona
authors.initials: N
authors.lastname: Sotoodehnia
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Emeny
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Johan G
authors.initials: JG
authors.lastname: Eriksson
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Denis A
authors.initials: DA
authors.lastname: Evans
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Luigi
authors.initials: L
authors.lastname: Ferrucci
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Myriam
authors.initials: M
authors.lastname: Fornage
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Vilmundur
authors.initials: V
authors.lastname: Gudnason
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Albert
authors.initials: A
authors.lastname: Hofman
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Thomas
authors.initials: T
authors.lastname: Illig
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Sharon
authors.initials: S
authors.lastname: Kardia
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Margaret
authors.initials: M
authors.lastname: Kelly-Hayes
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Karestan
authors.initials: K
authors.lastname: Koenen
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Peter
authors.initials: P
authors.lastname: Kraft
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Maris
authors.initials: M
authors.lastname: Kuningas
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Massaro
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: David
authors.initials: D
authors.lastname: Melzer
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Antonella
authors.initials: A
authors.lastname: Mulas
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Cornelis L
authors.initials: CL
authors.lastname: Mulder
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Anna
authors.initials: A
authors.lastname: Murray
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Ben A
authors.initials: BA
authors.lastname: Oostra
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Aarno
authors.initials: A
authors.lastname: Palotie
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Brenda
authors.initials: B
authors.lastname: Penninx
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Astrid
authors.initials: A
authors.lastname: Petersmann
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Luke C
authors.initials: LC
authors.lastname: Pilling
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Bruce
authors.initials: B
authors.lastname: Psaty
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Rajesh
authors.initials: R
authors.lastname: Rawal
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Eric M
authors.initials: EM
authors.lastname: Reiman
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Andrea
authors.initials: A
authors.lastname: Schulz
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Joshua M
authors.initials: JM
authors.lastname: Shulman
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Andrew B
authors.initials: AB
authors.lastname: Singleton
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Albert V
authors.initials: AV
authors.lastname: Smith
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Angelina R
authors.initials: AR
authors.lastname: Sutin
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: André G
authors.initials: AG
authors.lastname: Uitterlinden
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Henry
authors.initials: H
authors.lastname: Völzke
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Widen
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Kristine
authors.initials: K
authors.lastname: Yaffe
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Alan B
authors.initials: AB
authors.lastname: Zonderman
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Francesco
authors.initials: F
authors.lastname: Cucca
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Tamara
authors.initials: T
authors.lastname: Harris
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Ladwig
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: David J
authors.initials: DJ
authors.lastname: Llewellyn
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Katri
authors.initials: K
authors.lastname: Räikkönen
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Toshiko
authors.initials: T
authors.lastname: Tanaka
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Cornelia M
authors.initials: CM
authors.lastname: van Duijn
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Hans J
authors.initials: HJ
authors.lastname: Grabe
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Lenore J
authors.initials: LJ
authors.lastname: Launer
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Kathryn L
authors.initials: KL
authors.lastname: Lunetta
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Mosley
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Anne B
authors.initials: AB
authors.lastname: Newman
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Henning
authors.initials: H
authors.lastname: Tiemeier
authors.affiliation: Research Centre O3 (KH, CLM, HT), Department of Psychiatry, and Department of Epidemiology (KH, AH, MK, AGU, HT), Erasmus MC, Rotterdam, The Netherlands; Institute of Behavioural Sciences (JL, KRa), University of Helsinki, Helsinki, Finland; Clinical Research Branch (TT), National Institute on Aging, Baltimore, Maryland; Interfaculty Institute for Genetics and Functional Genomics (ATeu), University Medicine Greifswald, Greifswald, Germany; Department of Nutrition (MCC, FBH, EBR, MKJ), Harvard School of Public Health, Boston, Massachusetts; Department of Epidemiology (EB, AVD-R, SK), University of Michigan School of Public Health, Ann Arbor, Michigan; Institute of Epidemiology II (JB, RE, K-HL), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Internal Medicine (JD), Division of Geriatrics, and Department of Epidemiology and Prevention (YL), Division of Public Health Sciences, Wake Forest University, Winston-Salem, North Carolina; Department of Medicine (KM), Cardiovascular Health Research Unit, University of Washington, Seattle, Washington; National Institute on Aging (ATer, OM, ARS), National Institutes of Health, Department of Health and Human Services, Baltimore; and Laboratory of Neurogenetics (MAN, ABS), Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland; Department of Epidemiology (YVS), Emory University, Atlanta, Georgia; EMGO Institute for Health and Care Research (NV, BPe), and Department of Psychiatry (NV, BPe), VU University Medical Center, Amsterdam, The Netherlands; Rush Alzheimer's Disease Center (LY, DAB), and Department of Neurological Sciences (LY, DAB), Rush University Medical Center, Chicago, Illinois; Geriatric Unit Azienda Sanitaria di Firenze (SB), Firenze, Italy; National Heart, Lung, and Blood Institute's Framingham Heart Study (EJB, MK-H, JMM, KLL, JM), Framingham; and Department of Medicine (EJB), Section of Cardiology and Preventive Medicine, Boston University School of Medicine and Public Health, Boston, Massachusetts; Department of Biological Psychology (DB, EdG), VU University, Amsterdam, The Netherlands; Istituto di Ricerca Genetica e Biomedica (AC, AMul, FC), Consiglio Nazionale delle Ricerche, Monserrato, Cagliari, Italy; Division of Public Health Sciences (LHC), Wake Forest School of Medicine, Winston-Salem, North Carolina; Department of Neurology (PLDJ), Program in Translational NeuroPsychiatric Genomics, Brigham and Women's Hospital, Harvard Medical School, Boston; Department of Psychiatry (SP), Massachusetts General Hospital and Harvard Medical School, Boston, and the Broad Institute, Cambridge; and Department of Epidemiology (FBH, EBR), Harvard School of Public Health, Boston, Massachusetts; Department of Biostatistics (KRi), University of Washington, Seattle, Washington; Center of Biostatistics and Department of Medicine (ADP), University of Mississippi Medical Center, Jackson, Mississippi; Medical Genetics Institute (JIR), Cedars Sinai Medical Center, Los Angeles, California; Division of Cardiology (NS), and Cardiovascular Health Research Unit (NS), Department of Medicine, University of Washington, Seattle, Washington; National Institute for Health and Welfare (JGE); Department of General Practice and Primary Health Care (JGE), University of Helsinki; Unit of General Practice (JGE), Helsinki University Central Hospital; and Folkhalsan Research Centre (JGE), Helsinki; and Vasa Central Hospital (JGE), Vasa, Finland; Department of Internal Medicine (DAE), Rush Institute for Health Aging, Rush University Medical Center, Chicago, Illinois; Longitudinal Studies Section (LF), Clinical Research Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland; Brown Foundation Institute of Molecular Medicine (MF), University of Texas Health Science Center at Houston, Houston, Texas; Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging (AH, AGU, CMvD, HT), Leiden, The Netherlands; Research Unit of Molecular Epidemiology (TI), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Neurology (MK-H), Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology (KK), Mailman School of Public Health, Columbia University, New York, New York; Department of Biostatistics (JMM), Boston University School of Public Health, Boston, Massachusetts; Epidemiology and Public Health (DM, LCP, DJL), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Center for Medical Systems Biology (CMvD), Leiden, The Netherlands; Institute of Biomedical and Clinical Sciences (AMur), Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, United Kingdom; Mental Health Center BavoEuropoort (CLM), and Department of Clinical Genetics (BAO), Erasmus MC, Rotterdam, The Netherlands; Wellcome Trust Sanger Institute (APa), Wellcome Trust Genome Campus, Cambridge, United Kingdom; Institute for Molecular Medicine Finland (APa, EW), University of Helsinki, and Department of Medical Genetics (APa), University of Helsinki and University Central Hospital, Helsinki, Finland; Program in Medical and Population Genetics and Genetics Analysis Platform (APa), The Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts; Department of Psychiatry (BPe), Leiden University Medical Centre, Leiden, and Department of Psychiatry (BPe), University Medical Centre Groningen, Groningen, The Netherlands; Institute of Clinical Chemistry and Laboratory Medicine (APe), University Medicine Greifswald, Greifswald, Germany; Cardiovascular Health Research Unit (BPs), Departments of Medicine, Epidemiology, and Health Services, University of Washington, and Group Health Research Institute (BPs), Group Health Cooperative, Seattle, Washington; Institute of Genetic Epidemiology (RR), Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Neurogenomics Division (EMR), Translational Genomics Research Institute, and Banner Alzheimer's Institute (EMR), Phoenix, Arizona; Department of Psychiatry and Psychotherapy (AS, HJG), University Medicine Greifswald, Helios-Hospital, Stralsund, Germany; Laboratory of Behavioral Neuroscience (ABZ), National Institute on Aging, Baltimore, Maryland; Department of Internal Medicine (AGU), Erasmus MC, Rotterdam, The Netherlands; Institute for Community Medicine (HV), University Medicine Greifswald, Germany; Department of Psychiatry (KY), University of California San Francisco, San Francisco, California; Icelandic Heart Association (VG, AVS), Kopavogur, Iceland; Departments of Neurology (KY) and Epidemiology and Biostatistics (KY), University of California San Francisco, San Francisco, California; Laboratory of Epidemiology, Demography and Biometry (TH, LJL), National Institute on Aging, Bethesda, Maryland; Department of Biostatistics (KLL), Boston University School of Public Health, Boston, Massachusetts; Department of Medicine (THM), University of Mississippi Medical Center, Jackson, Mississippi; Department of Medicine (JM), Section of General Internal Medicine, Boston University School of Medicine; Program in Molecular and Genetic Epidemiology (DJH, PK), Harvard School of Public Health; and Brigham and Women's Hospital (GC), Harvard Medical School, Boston, Massachusetts; Department of Epidemiology (ABN), Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Medicine (VG, AVS), University of Iceland, Reykjavik, Iceland; Hannover Unified Biobank (TI), Hannover Medical School, Hannover, Germany; College of Medicine (ATer, ARS), Florida State University, Tallahassee, Florida; Genetic Epidemiology Unit (AD, NA, BAO, CMvD), Departments of Epidemiology and Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands; and Departments of Neurology and Molecular Human Genetics (JMS), Baylor College of Medicine, Houston, Texas.
authors.forename: Joanne
authors.initials: J
authors.lastname: Murabito
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002895:Chromosomes, Human, Pair 5 / Q000235:genetics; D003863:Depression / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D055106:Genome-Wide Association Study; D006801:Humans; D008297:Male; D008875:Middle Aged; D020641:Polymorphism, Single Nucleotide / Q000235:genetics