title: Local auxin biosynthesis regulation by PLETHORA transcription factors controls phyllotaxis in Arabidopsis.
abstract: Lateral organ distribution at the shoot apical meristem defines specific and robust phyllotaxis patterns that have intrigued biologists and mathematicians for centuries. In silico studies have revealed that this self-organizing process can be recapitulated by modeling the polar transport of the phytohormone auxin. Phyllotactic patterns change between species and developmental stages, but the processes behind these variations have remained unknown. Here we use regional complementation experiments to reveal that phyllotactic switches in Arabidopsis shoots can be mediated by PLETHORA-dependent control of local auxin biosynthesis.
authors.affiliation: Molecular Genetics, Department of Biology, Faculty of Science,  Utrecht University, 3584 CH Utrecht,  The Netherlands.
authors.forename: Violaine
authors.initials: V
authors.lastname: Pinon
authors.forename: Kalika
authors.initials: K
authors.lastname: Prasad
authors.forename: Stephen P
authors.initials: SP
authors.lastname: Grigg
authors.forename: Gabino F
authors.initials: GF
authors.lastname: Sanchez-Perez
authors.forename: Ben
authors.initials: B
authors.lastname: Scheres
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D019521:Body Patterning; D018507:Gene Expression Regulation, Developmental; D018506:Gene Expression Regulation, Plant; D017343:Genes, Plant; D007210:Indoleacetic Acids / Q000378:metabolism*; D026901:Membrane Transport Proteins / Q000235:genetics / Q000378:metabolism; D018519:Meristem / Q000254:growth & development / Q000378:metabolism; D009154:Mutation; D010937:Plant Growth Regulators / Q000096:biosynthesis; D030821:Plants, Genetically Modified; D015398:Signal Transduction; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D029681:Arabidopsis Proteins; D007210:Indoleacetic Acids; D026901:Membrane Transport Proteins; C116363:PIN1 protein, Arabidopsis; D010937:Plant Growth Regulators; D014157:Transcription Factors