title: A new monoterpenoid oxindole alkaloid from Hamelia patens micropropagated plantlets.
abstract: Chemical studies on Hamelia patens (Rubiaceae) micropropagated plantlets allowed production of a new monoterpenoid oxindole alkaloid, named (-)-hameline (7), together with eight known alkaloids, tetrahydroalstonine (1), aricine (2), pteropodine (3), isopteropodine (4), uncarine F (5), speciophylline (6), palmirine (8), and rumberine (9). The structure of the new alkaloid was assigned on the basis of 1D and 2D NMR spectroscopy, mass spectrometry, and molecular modeling.
authors.affiliation: Departamento de Biotecnología y Bioingeniería, Centro de Investigación y de Estudios Avanzados del Instituto Nacional, Av. Instituto Politécnico Nacional 2508, Col. San Pedro Zacatenco, 07360 Mexico D. F., Mexico.
authors.forename: David
authors.initials: D
authors.lastname: Paniagua-Vega
authors.forename: Carlos M
authors.initials: CM
authors.lastname: Cerda-García-Rojas
authors.forename: Teresa
authors.initials: T
authors.lastname: Ponce-Noyola
authors.forename: Ana C
authors.initials: AC
authors.lastname: Ramos-Valdivia
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D046508:Culture Techniques; D032063:Hamelia / Q000737:chemistry*; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D000470:Alkaloids; D039821:Monoterpenes