title: (1)H and (13)C NMR Assignments of Cytotoxic 3S-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid from the Leaves of Cichorium endivia.
abstract: An amino acid, 3S-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid, was isolated for the first time from the leaves of Cichorium endivia. The complete assignment of its (1)H and (13)C NMR spectroscopic data was carried out also for the first time based on extensive 1D and 2D NMR experiments. Cytotoxicity of this isolated compound against HCT-8 and HepG2 human cancer cell lines was evaluated for the first time, with moderate activities being found.
authors.affiliation: Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors.forename: Fu-Xin
authors.initials: FX
authors.lastname: Wang
authors.forename: An-Jun
authors.initials: AJ
authors.lastname: Deng
authors.forename: Jin-Feng
authors.initials: JF
authors.lastname: Wei
authors.forename: Hai-Lin
authors.initials: HL
authors.lastname: Qin
authors.forename: Ai-Ping
authors.initials: AP
authors.lastname: Wang