title: Coated vs uncoated implants: bone defect configurations after progressive peri-implantitis in dogs.
abstract: In this study, hydroxyapatite coated vs uncoated implants were used to evaluate the type and dimensions of bone defects after progressive peri-implantitis in dogs. Thirty-two dental implants with 4 different surfaces-machined (M), sandblasted acid-etched (SA), 1-μm thin sputter hydroxyapatite (HA)-coated (S), and plasma-sprayed HA-coated (P)-were inserted into the mandibles of 4 beagle dogs after extracting all mandibular premolars. Experimental peri-implantitis was induced after 3 months using ligature to allow for plaque accumulation. After 4 months, ligatures were removed and plaque accumulation continued for 5 months (progression period). The open flap surgery demonstrated 3 patterns of peri-implantitis bone defect: (1) Class I defect: represented as circumferential intra-alveolar bone loss; (2) Class II defect: circumferential intra-alveolar defect with supra-alveolar bone loss exposing the implant surface; and (3) Class III defect: represented as circumferential intra-alveolar defect with supra-alveolar bone loss and buccal dehiscence. Class I was the most frequent (62.5%) defect pattern around implant types M, SA, and S; while implant type-P showed a recurring majority of Class II (62.5%). Comparison among the 4 implant groups revealed a significant defect width (DW) in implant type-P relative to other types (P < 0.01). However, no statistically significant differences were noted for defect depth (DD) (P > 0.05). We concluded that the shape and size of peri-implantitis bone defects were influenced by the type and thickness of the HA coat together with the quantity of the available peri-implant bone. Plasma-sprayed HA-coated implants showed larger peri-implant defects than did thin sputter HA-coated implants.
authors.affiliation: 1  Department of Oral Implantology and Regenerative Dental Medicine, Tokyo Medical and Dental University, and Global Center of Excellence (GCOE), Tokyo Medical and Dental University, Tokyo, Japan.
authors.forename: Marwa
authors.initials: M
authors.lastname: Madi
authors.forename: Osama
authors.initials: O
authors.lastname: Zakaria
authors.forename: Shohei
authors.initials: S
authors.lastname: Kasugai
mesh_terms: D000134:Acid Etching, Dental / Q000379:methods; D000539:Alveolar Process / Q000473:pathology* / Q000601:surgery; D000818:Animals; D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D045662:Dental Etching / Q000379:methods; D015921:Dental Implants; D003773:Dental Plaque / Q000150:complications; D018450:Disease Progression; D004285:Dogs; D017886:Durapatite / Q000737:chemistry*; D005260:Female; D008334:Mandible / Q000601:surgery; D057873:Peri-Implantitis / Q000145:classification* / Q000473:pathology / Q000601:surgery; D058626:Plasma Gases / Q000737:chemistry; D011897:Random Allocation; D013499:Surface Properties; D013524:Surgical Flaps / Q000601:surgery
chemical_list: D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D058626:Plasma Gases; D017886:Durapatite
keywords: bone defects; dental implants; hydroxyapatite coat; peri-implantitis