title: [Hereditary antithrombin deficiency and hyperhomocysteinemia in venous thromboembolic disease].
abstract: Hypercoagulability state is the result of the interplay of genetic predisposition and risk factors. Many key enzymes and reactions in coagulation and anti-coagulation system are involved. Hereditary antithrombin deficiency is one of the major risk factors of venous thromboembolic disease (VTE), whereas hyperhomocysteinemia may also play a role. This article reviews the recent researches on the contributions of these two factors to VTE.
authors.affiliation: Department of Vascular Surgery, PUMC Hospital, CAMS and PUMC, Beijing, China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Xi-xi
authors.forename: Bing
authors.initials: B
authors.lastname: Zhong-xing
authors.forename: Liu
authors.initials: L
authors.lastname: Bao
mesh_terms: D020152:Antithrombin III Deficiency / Q000150:complications*; D006801:Humans; D020138:Hyperhomocysteinemia / Q000150:complications*; D020246:Venous Thrombosis / Q000209:etiology*