title: [Single center experience of primary percutaneous coronary intervention on left main disease complicated by acute myocardial infarction].
abstract: OBJECTIVE
  To explore the clinical effect of primary percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) induced by left main artery total or subtotal occlusion.
  
  
  METHODS
  Between January 1995 and June 2010, there were 28 AMI patients [24 males, mean age (61.5 ± 2.3) years, 15 patients complicated with cardiac shock] with left main occlusion or severe stenosis who were treated with PCI in our center. The clinical features were compared between death group and survival group. All survival cases were prospectively followed up for the occurrence of major adverse cardiac events.
  
  
  RESULTS
  Totally 25 patients received stent implantation, 2 received balloon dilation followed by coronary artery bypass graft, and 1 patient died during PCI. Total in-hospital mortality was 35.7% (10/28), and mortality was 53.3% (8/15) in cardiac shock patients. Compared with survival group, ratio of cardiac shock [80.0% (8/10) vs.38.9% (7/18), P < 0.05] and poor collateral circulation flow [100% (10/10) vs. 33.3% (6/18), P < 0.01] were higher in death group, and there was no significant difference in TIMI 3 grade of forward flow post procedure (P > 0.05). Hospital stay was (22.1 ± 2.6) days and the cumulative survival was 64.3% during 3 months follow up for survival group.
  
  
  CONCLUSIONS
  Short-term clinical outcome is favorable for survived AMI patients with left main disease who underwent PCI. The ratio of cardiac shock and poor collateral circulation flow are risk factors for in-hospital death in AMI patients with left main disease who underwent PCI.
authors.affiliation: Heart Center, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
authors.forename: Le-feng
authors.initials: LF
authors.lastname: Wang
authors.forename: Da-peng
authors.initials: DP
authors.lastname: Zhang
authors.forename: Xin-chun
authors.initials: XC
authors.lastname: Yang
authors.forename: Li
authors.initials: L
authors.lastname: Xu
authors.forename: Yong-gui
authors.initials: YG
authors.lastname: Ge
authors.forename: Hong-shi
authors.initials: HS
authors.lastname: Wang
authors.forename: Wei-ming
authors.initials: WM
authors.lastname: Li
authors.forename: Zhu-hua
authors.initials: ZH
authors.lastname: Ni
authors.forename: Kun
authors.initials: K
authors.lastname: Xia
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003324:Coronary Artery Disease / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000473:pathology* / Q000628:therapy*; D062645:Percutaneous Coronary Intervention; D012307:Risk Factors; D016896:Treatment Outcome