title: Comparison between the radionuclide salivagram and videofluoroscopic swallowing study methods for evaluating patients with aspiration pneumonia.
abstract: OBJECTIVE
  A videofluoroscopic swallowing study (VFSS) is generally used to assess dysphagia and aspiration, although false-negative results may be obtained. Saliva aspiration may cause false-negative VFSS findings in elderly people. A radionuclide salivagram can be useful in detecting saliva aspiration. We therefore compared these two methods for the evaluation of patients with aspiration pneumonia.
  
  
  METHODS
  We prospectively enrolled 50 patients with aspiration pneumonia into this study. All patients underwent VFSS, and were evaluated on the Penetration-Aspiration Scale. A salivagram was performed on the day after VFSS and each patient received 1 mL Tc-99 m DTPA sublingually. Both dynamic and delayed images were obtained.
  
  
  RESULTS
  Aspiration was observed in 34% of patients by salivagram and in 42% by VFSS. The frequency of tests that were positive for aspiration pneumonia using a combination of the two methods was 52%. Five patients with positive aspiration findings on salivagram were negative on VFSS. The association between VFSS and salivagram findings was significant but the total agreement was 72%. The frequency of aspiration pneumonia was significantly associated with an abnormal salivagram finding.
  
  
  CONCLUSIONS
  A salivagram may be a useful method for the evaluation of aspiration in elderly people, and a combination of the VFSS and salivagram methods could enable a more effective investigation of aspiration pneumonia.
authors.affiliation: Department of Rehabilitation, Incheon St. Mary's Hospital, The Catholic University of Korea, Incheon, Korea.
authors.forename: Dae-Hyun
authors.initials: DH
authors.lastname: Jang
authors.forename: Kyoung Hyo
authors.initials: KH
authors.lastname: Choi
authors.forename: Dae Ha
authors.initials: DH
authors.lastname: Kim
authors.forename: Chae-Man
authors.initials: CM
authors.lastname: Lim
authors.forename: Jae Seung
authors.initials: JS
authors.lastname: Kim
mesh_terms: D000368:Aged; D002933:Cineradiography / Q000379:methods*; D003679:Deglutition; D005260:Female; D006801:Humans; D008297:Male; D011015:Pneumonia, Aspiration / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011877:Radionuclide Imaging / Q000379:methods*; D012463:Saliva / Q000000981:diagnostic imaging* / Q000378:metabolism