title: [Symbiotic interactions of corynebacteria and lactobacilli in realization of oxidative mechanisms of antagonism].
abstract: OBJECTIVE
  Study the interaction of vaginal corynebacteria and lactobacilli in realization of oxidative mechanism of antagonistic relations of bacteria.
  
  
  METHODS
  Effect of supernatants of corynebacteria inhibiting catalase on antagonism of peroxide producing lactobacilli to Staphylococcus aureus was studied.
  
  
  RESULTS
  High frequency (55.5 - 72.7%) of potentiating of antagonism of lactobacilli with medium and high level of hydrogen peroxide production under the effect of supernatants of corynebacteria inhibiting catalase was established. The frequency of potentiation of antagonism of lactobacilli and corynebacteriae depended on the intensity of hydrogen peroxide production and on the ability of corynebacteria to suppress catalase of staphylococci.
  
  
  CONCLUSIONS
  Potentiation of antagonism to S. aureus of peroxide producing lactobacilli and corynebacteria with catalase inhibitors gives evidence on realization of oxidative bacterial mechanism of colonization resistance in human organism.
authors.forename: S V
authors.initials: SV
authors.lastname: Cherkasov
authors.forename: I V
authors.initials: IV
authors.lastname: Gladysheva
authors.forename: O V
authors.initials: OV
authors.lastname: Bukharin
mesh_terms: D000898:Antibiosis; D002374:Catalase / Q000037:antagonists & inhibitors* / Q000378:metabolism; D003352:Corynebacterium / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D017077:Culture Media, Conditioned / Q000494:pharmacology; D005260:Female; D006801:Humans; D006861:Hydrogen Peroxide / Q000378:metabolism / Q000494:pharmacology; D007778:Lactobacillus / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D010084:Oxidation-Reduction; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D013559:Symbiosis / Q000502:physiology*; D014621:Vagina / Q000382:microbiology
chemical_list: D017077:Culture Media, Conditioned; D006861:Hydrogen Peroxide; D002374:Catalase