title: Antiproliferative activities of tea and herbal infusions.
abstract: The consumption of tea and herbal infusions has increased rapidly in recent years. More and more people consume these infusions as daily beverages as well as for health purposes. The aim of this study was to supply new information on the antiproliferative function of these infusions for nutritionists and the general public. The in vitro antiproliferative activities of 60 different tea and herbal infusions on four cancer cell lines were evaluated by MTT assay. The results showed that some infusions strongly inhibited the proliferation of A549 (human lung cancer cells), MCF-7 (human breast cancer cells), HepG2 (human hepatoma cells) and HT-29 (human colon cancer cells), and decreased the viability of these cancer cell lines in a dose-dependent manner. In addition, some bioactive components in the infusions were also separated and determined by HPLC. The results suggested that some tea and herbal infusions may be potential dietary supplements for the prevention and treatment of cancer.
authors.affiliation: Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Li
authors.forename: Sha
authors.initials: S
authors.lastname: Li
authors.forename: Hua-Bin
authors.initials: HB
authors.lastname: Li
authors.forename: Gui-Fang
authors.initials: GF
authors.lastname: Deng
authors.forename: Wen-Hua
authors.initials: WH
authors.lastname: Ling
authors.forename: Xiang-Rong
authors.initials: XR
authors.lastname: Xu
mesh_terms: D001628:Beverages / Q000032:analysis*; D028241:Camellia sinensis / Q000737:chemistry*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects*; D006801:Humans; D009369:Neoplasms / Q000503:physiopathology* / Q000517:prevention & control; D028321:Plant Preparations / Q000032:analysis / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D013662:Tea / Q000737:chemistry*
chemical_list: D028321:Plant Preparations; D013662:Tea