title: [Comparison of long-term clinical outcomes between descemet's stripping endothelial keratoplasty and deep lamellar endothelial keratoplasty].
abstract: OBJECTIVE
  To investigate the differences of long-term clinical outcomes between two kinds of corneal endothelial keratoplasty (EK): DSEK and DLEK.
  
  
  METHODS
  Retrospective, comparative, clinical case series study. Twenty-six patients (26 eyes), undergoing DLEK and thirty-six patients (36 eyes), undergoing DSEK during the period of October 2005 to March 2008, were involved in this study. Before and at 6 month intervals after surgery, patients' data were collected to analyze the surgery success rate, graft dislocation rate, best corrected visual acuity (BSCVA), graft survival rate and endothelial cell density (ECD). The follow-up time was 3 to 5 years.
  
  
  RESULTS
  The success rate of DLEK was 88.5% while DSEK was 86.1%. Average BSCVA of DLEK were similar to those of DSEK at each follow-up time after 12 months postoperatively. Graft survival rates of DLEK and DSEK were respectively 87% and 75.9%, where as ECD were respectively 1638 cells/mm(2) and 1874 cells/mm(2) at 36 month postoperatively, the data were similar in both ECD and graft survival rate between DLEK and DSEK at 60 months postoperatively.
  
  
  CONCLUSIONS
  The success rate and long-term visual outcomes of DLEK were similar with those of DSEK. To obtain objective results, it is better to consider both ECD and graft survival rate instead of recording ECD only for its localization in evaluating the efficacy of EK.
authors.affiliation: Sun Yat-sen University, Guangzhou, China. thuang@vip.163.com
authors.forename: Ting
authors.initials: T
authors.lastname: Huang
authors.forename: Na
authors.initials: N
authors.lastname: Gao
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.forename: Yu-juan
authors.initials: YJ
authors.lastname: Wang
authors.forename: Yun
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D016039:Corneal Transplantation / Q000379:methods*; D057111:Descemet Stripping Endothelial Keratoplasty / Q000379:methods*; D004728:Endothelium, Corneal / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult