title: Management of chronic obstructive pulmonary disease in the Middle East and North Africa: results of the BREATHE study.
abstract: Chronic obstructive pulmonary disease (COPD) is a potentially severe chronic progressive respiratory condition requiring long-term treatment and frequently involving episodic hospitalisations to manage exacerbations. The objective of this analysis was to document diagnosis, evaluation, treatment and management of COPD-related respiratory symptoms in 1,392 subjects fulfilling an epidemiological definition of COPD identified in a general population sample of 62,086 individuals aged ≥ 40 years in ten countries in the Middle East and North Africa region (Algeria, Egypt, Jordan, Lebanon, Morocco, Saudi Arabia, Syria, Tunisia, Turkey and United Arab Emirates), together with Pakistan. 442 subjects (31.8%) claimed to have received a diagnosis of COPD from a physician and 287 (20.6%) had undergone spirometry in the previous year. Use of specific treatments for respiratory symptoms was reported by 218 subjects (15.7%). Use of inhaled long-acting bronchodilators together with corticosteroids (53 subjects; 3.8%) and use of oxygen therapy (31 subjects; 2.3%) was very low. 852 subjects (61.2%) had consulted a physician about their respiratory condition at least once in the previous year, with a mean number of consultations of 3.4 ± 3.6. Moreover, 284 subjects (20.4%) had been hospitalised overnight for their COPD, with a mean of 2.3 ± 3.7 hospitalisations per year. Use of all healthcare resources was significantly higher (p < 0.001) in subjects with CAT scores ≥ 10 than in those with scores < 10, and greater in those with exacerbations than in those without. In conclusion, COPD in the region is under-diagnosed, inadequately evaluated and inadequately treated. Nonetheless, COPD symptoms are responsible for considerable healthcare consumption, with high levels of physician consultation and hospitalisation.
authors.affiliation: Riyadh Military Hospital, Riyadh, Saudi Arabia.
authors.forename: Majdy
authors.initials: M
authors.lastname: Idrees
authors.forename: Marie-Louise
authors.initials: ML
authors.lastname: Koniski
authors.forename: Samya
authors.initials: S
authors.lastname: Taright
authors.forename: Naeem
authors.initials: N
authors.lastname: Shahrour
authors.forename: Mehmet
authors.initials: M
authors.lastname: Polatli
authors.forename: Ali
authors.initials: A
authors.lastname: Ben Kheder
authors.forename: Ashraf
authors.initials: A
authors.lastname: Alzaabi
authors.forename: Ghali
authors.initials: G
authors.lastname: Iraqi
authors.forename: Adel
authors.initials: A
authors.lastname: Khattab
authors.forename: Arshad
authors.initials: A
authors.lastname: Javed
authors.forename: Nauman
authors.initials: N
authors.lastname: Rashid
authors.forename: Abdelkader
authors.initials: A
authors.lastname: El Hasnaoui
mesh_terms: D000328:Adult; D000352:Africa, Northern / Q000453:epidemiology; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D006295:Health Resources / Q000706:statistics & numerical data; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D008877:Middle East / Q000453:epidemiology; D009819:Office Visits / Q000706:statistics & numerical data; D010154:Pakistan / Q000453:epidemiology; D010342:Patient Acceptance of Health Care / Q000706:statistics & numerical data; D029424:Pulmonary Disease, Chronic Obstructive / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D012720:Severity of Illness Index; D016540:Smoking Cessation / Q000706:statistics & numerical data; D013147:Spirometry / Q000706:statistics & numerical data