title: Integration of genomics in cancer care.
abstract: OBJECTIVE
  The article aims to introduce nurses to how genetics-genomics is currently integrated into cancer care from prevention to treatment and influencing oncology nursing practice.
  
  
  METHODS
  An overview of genetics-genomics is described as it relates to cancer etiology, hereditary cancer syndromes, epigenetics factors, and management of care considerations.
  
  
  METHODS
  Peer-reviewed literature and expert professional guidelines were reviewed to address concepts of genetics-genomics in cancer care.
  
  
  RESULTS
  Cancer is now known to be heterogeneous at the molecular level, with genetic and genomic factors underlying the etiology of all cancers. Understanding how these factors contribute to the development and treatment of both sporadic and hereditary cancers is important in cancer risk assessment, prevention, diagnosis, treatment, and long-term management and surveillance.
  
  
  CONCLUSIONS
  Rapidly developing advances in genetics-genomics are changing all aspects of cancer care, with implications for nursing practice.
  
  
  CONCLUSIONS
  Nurses can educate cancer patients and their families about genetic-genomic advances and advocate for use of evidence-based genetic-genomic practice guidelines to reduce cancer risk and improve outcomes in cancer management.
authors.affiliation: Hospital A.C. Camargo, CIPE - Center for Research and Teaching, and National Institute of Oncogenomics, Sao Paulo, Brazil.
authors.forename: Erika Maria Monteiro
authors.initials: EM
authors.lastname: Santos
authors.forename: Quannetta T
authors.initials: QT
authors.lastname: Edwards
authors.forename: Milena
authors.initials: M
authors.lastname: Floria-Santos
authors.forename: Silvia Regina
authors.initials: SR
authors.lastname: Rogatto
authors.forename: Maria Isabel Waddington
authors.initials: MI
authors.lastname: Achatz
authors.forename: Deborah J
authors.initials: DJ
authors.lastname: MacDonald
mesh_terms: D005817:Genetic Counseling; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D015894:Genome, Human; D023281:Genomics / Q000193:education; D006801:Humans; D009369:Neoplasms / Q000235:genetics* / Q000451:nursing*; D024802:Nurse's Role; D009859:Oncology Nursing; D010353:Patient Education as Topic; D057285:Precision Medicine