title: A mild and efficient one-pot synthesis of β-amino carbonyl compounds via Mannich reaction under ambient temperature condition.
abstract: We have developed an efficient protocol for the synthesis of β-amino carbonyl compounds using phenylboronic acid as effective and eco-friendly catalyst via one-pot three-component Mannich reaction. Excellent yields, mild reaction condition, and simple experimental work-up procedure are some of the advantages of this method, which makes it a useful protocol for the synthesis of β-amino carbonyl compounds.
authors.affiliation: Department of Chemistry, Dnyanopasak College, Parbhani, 431 401, Maharashtra, India.
authors.forename: Santosh V
authors.initials: SV
authors.lastname: Goswami
authors.forename: Prashant B
authors.initials: PB
authors.lastname: Thorat
authors.forename: Avinash V
authors.initials: AV
authors.lastname: Chakrawar
authors.forename: Sudhakar R
authors.initials: SR
authors.lastname: Bhusare
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000814:Aniline Compounds / Q000138:chemical synthesis*; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D047188:Chalcones / Q000138:chemical synthesis*; D060326:Chemistry Techniques, Synthetic; D007659:Ketones / Q000138:chemical synthesis*; D008352:Mannich Bases / Q000737:chemistry; D015394:Molecular Structure
chemical_list: D000447:Aldehydes; D000814:Aniline Compounds; D001897:Boronic Acids; D047188:Chalcones; D007659:Ketones; D008352:Mannich Bases; C010686:benzeneboronic acid