title: Software for automated interpretation of mass spectrometry data from glycans and glycopeptides.
abstract: The purpose of this review is to provide those interested in glycosylation analysis with the most updated information on the availability of automated tools for MS characterization of N-linked and O-linked glycosylation types. Specifically, this review describes software tools that facilitate elucidation of glycosylation from MS data on the basis of mass alone, as well as software designed to speed the interpretation of glycan and glycopeptide fragmentation from MS/MS data. This review focuses equally on software designed to interpret the composition of released glycans and on tools to characterize N-linked and O-linked glycopeptides. Several websites have been compiled and described that will be helpful to the reader who is interested in further exploring the described tools.
authors.affiliation: Department of Chemistry, University of Kansas, 2030 Becker Drive, Lawrence, KS 66047, USA.
authors.forename: Carrie L
authors.initials: CL
authors.lastname: Woodin
authors.forename: Morgan
authors.initials: M
authors.lastname: Maxon
authors.forename: Heather
authors.initials: H
authors.lastname: Desaire
mesh_terms: D001331:Automation; D006020:Glycopeptides / Q000032:analysis* / Q000737:chemistry*; D006031:Glycosylation; D013058:Mass Spectrometry / Q000379:methods*; D011134:Polysaccharides / Q000032:analysis* / Q000737:chemistry*; D012984:Software
chemical_list: D006020:Glycopeptides; D011134:Polysaccharides