title: Cu(II)-catalyzed cyclization of α-diazo-β-oxoamides with amines leading to pyrrol-3(2H)-ones.
abstract: A novel Cu(II)-catalyzed cyclization of α-diazo-β-oxoamides with amines has been developed, constituting a straightforward method to construct pyrrol-3(2H)-one rings. The intramolecular hydrogen bonding effect in α-diazo-β-oxoamides plays an essential role in this reaction. A plausible reaction mechanism involving divergent generation and subsequent [2 + 3] cyclization of ketene and α-diazoimine intermediates was proposed.
authors.affiliation: Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China.
authors.forename: Zikun
authors.initials: Z
authors.lastname: Wang
authors.forename: Xihe
authors.initials: X
authors.lastname: Bi
authors.forename: Peiqiu
authors.initials: P
authors.lastname: Liao
authors.forename: Xu
authors.initials: X
authors.lastname: Liu
authors.forename: Dewen
authors.initials: D
authors.lastname: Dong