title: Management of patients with hematological malignancies undergoing coronary artery bypass grafting.
abstract: The number of patients with a previously diagnosed malignancy who need cardiac surgery is increasing. Patients with hematological malignancies represent only 0.38% of all patients undergoing cardiac surgery. The literature in this subset of patients is limited to only a few retrospective case series, with limited number of patients undergoing emergency cardiac surgery. We describe three cases with hematological malignancies namely chronic myelogenous leukemia, acute promyelocytic leukemia and chronic lymphocytic leukemia presenting for coronary artery bypass grafting (CABG). Two patients were taken up for emergency CABG in view of ongoing ischemia, one of them was on preoperative intra-aortic balloon pump support. No mortality was observed. Two patients needed transfusion of blood products which was guided by thromboelastography. One patient developed superficial sternal wound infection requiring antibiotic therapy.
authors.affiliation: Department of Cardiac Anesthesia, P.D. Hinduja National Hospital and Medical Research Centre, Mahim Fortis Hospitals, Mulund, Lilavati Hospital, Bandra, Mumbai, Maharashtra, India.
authors.forename: Deepak
authors.initials: D
authors.lastname: Borde
authors.forename: Uday
authors.initials: U
authors.lastname: Gandhe
authors.forename: Neha
authors.initials: N
authors.lastname: Hargave
authors.forename: Kaushal
authors.initials: K
authors.lastname: Pandey
mesh_terms: D000368:Aged; D000768:Anesthesia, General; D001803:Blood Transfusion; D002637:Chest Pain / Q000209:etiology; D001026:Coronary Artery Bypass / Q000379:methods*; D003324:Coronary Artery Disease / Q000601:surgery; D003331:Coronary Vessels / Q000601:surgery*; D005260:Female; D019337:Hematologic Neoplasms / Q000150:complications / Q000628:therapy*; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications / Q000628:therapy; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications / Q000628:therapy; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications / Q000628:therapy; D008297:Male; D008875:Middle Aged; D013530:Surgical Wound Infection / Q000628:therapy; D013916:Thrombelastography