title: Neonatal renal venous thrombosis followed by secondary pseudohypoaldosteronism.
abstract: A male infant was diagnosed as having renal venous thrombosis (RVT) in association with bilateral flank masses, macroscopic hematuria, and thrombocytopenia. In the course of supportive treatment, hyponatremia, hyperkalemia, and metabolic acidosis became prominent. Plasma renin activity (PRA) and aldosterone increased markedly. Treatment with sufficient sodium chloride and sodium bicarbonate intake was effective. It is important to note that tubular damage by RVT causes secondary pseudohypoaldosteronism.
authors.affiliation: Department of Pediatrics, Seirei-Mikatahara General Hospital, Shizuoka, Japan. h-nakashima@mvd.biglobe.ne.jp
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Nakashima
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Kibe
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Ohro
authors.forename: Naoya
authors.initials: N
authors.lastname: Fujita
mesh_terms: D000450:Aldosterone / Q000097:blood*; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011546:Pseudohypoaldosteronism / Q000097:blood / Q000150:complications*; D012082:Renal Veins; D014463:Ultrasonography; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*
chemical_list: D000450:Aldosterone