title: [The hormonal metabolic alterations in patients in critical state].
abstract: It is established that in patients in critical state occur significant alterations of hormone metabolic parameters. In severe cases, hypermetabolism-hyperkatabolism syndrome is developed. Under this syndrome, the resistance to exogenous introduction of nutrients occurs. The syndrome plays a key role in in pathogenesis of critical state and its course in many respects determine outcome of disease. The article describes in detail the pathogenesis of all cascades of pathologic reactions in severe ill patients subject to pathogenic mechanism of development. The possible approaches to resolve this complicated issue are presented.
authors.forename: A V
authors.initials: AV
authors.lastname: Selivanova
mesh_terms: D050260:Carbohydrate Metabolism; D016638:Critical Illness / Q000628:therapy; D005215:Fasting / Q000378:metabolism; D044882:Glucose Metabolism Disorders / Q000378:metabolism; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism / Q000503:physiopathology; D050356:Lipid Metabolism; D009104:Multiple Trauma / Q000378:metabolism* / Q000503:physiopathology / Q000628:therapy; D010913:Pituitary-Adrenal System / Q000378:metabolism / Q000503:physiopathology; D011502:Protein-Energy Malnutrition / Q000378:metabolism; D011506:Proteins / Q000378:metabolism*; D018746:Systemic Inflammatory Response Syndrome / Q000378:metabolism
chemical_list: D006728:Hormones; D011506:Proteins