title: Cutaneous and leptomeningeal hemangiomas with impressive benign evolution.
abstract: We describe an infant with cutaneous and leptomeningeal diffuse hemangiomata. Clinical facial anomalies were evident at birth. Routine transfontanellar ultrasonography revealed very diffuse leptomeningeal hemangioma. Magnetic resonance imaging during the first days of age confirmed vascular lesions. The patient was otherwise normal, and was monitored at ages 3.5, 9, and 18 months. Rapid resolution of the hemangioma occurred within 1 year. The infant did not present with persistent embryonic arteries, a posterior fossa, or other malformations typically reported in Pascual-Castroviejo type II syndrome. However, the characteristic skin color, leptomeningeal hemangioma, and rapid involution prompted the diagnosis of Pascual-Castroviejo II syndrome in its wider, benign spectrum.
authors.affiliation: Department of Pediatrics and Pediatric Emergencies, University Hospital Policlinico-Vittorio Emanuele, Catania, Italy.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Falsaperla
authors.forename: Piero
authors.initials: P
authors.lastname: Pavone
authors.forename: Martino
authors.initials: M
authors.lastname: Ruggieri
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Pavone
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis*; D018450:Disease Progression; D005500:Follow-Up Studies; D006391:Hemangioma / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D008113:Liver Neoplasms / Q000175:diagnosis*; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D008578:Meninges / Q000473:pathology; D012867:Skin / Q000473:pathology