title: A novel sperm-activating and attracting factor from the ascidian Ascidia sydneiensis.
abstract: A novel SAAF was isolated from the title ascidian. The structure was elucidated using the entire sample of 4 nmol, suggesting that the position of the OH group confers genus-specificity to sperm chemotaxis in ascidians. This study not only provides insight into the chemical tactics in sperm chemotaxis but demonstrates that the innovative techniques allow structure determination of natural products in trace amounts.
authors.affiliation: Department of Chemistry, Graduate School of Science, Osaka Universit , Toyonaka, Osaka 560-0043, Japan. matsmori@chem.sci.osaka-u.ac.jp
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Matsumori
authors.forename: Yuki
authors.initials: Y
authors.lastname: Hiradate
authors.forename: Hajime
authors.initials: H
authors.lastname: Shibata
authors.forename: Tohru
authors.initials: T
authors.lastname: Oishi
authors.forename: Shuichi
authors.initials: S
authors.lastname: Shimma
authors.forename: Michisato
authors.initials: M
authors.lastname: Toyoda
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Hayashi
authors.forename: Manabu
authors.initials: M
authors.lastname: Yoshida
authors.forename: Michio
authors.initials: M
authors.lastname: Murata
authors.forename: Masaaki
authors.initials: M
authors.lastname: Morisawa
mesh_terms: D000818:Animals; D002777:Cholestanols / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism; D008297:Male; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D013094:Spermatozoa / Q000502:physiology*; D013329:Structure-Activity Relationship; D013463:Sulfuric Acid Esters / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism; D014561:Urochordata / Q000737:chemistry* / Q000235:genetics
chemical_list: C533418:3,4,7,26-tetrahydroxycholestane-3,26-disulfate; D002777:Cholestanols; D013463:Sulfuric Acid Esters; C580607:sperm-activating and attracting factor, Ascidia sydneiensis