title: Inherited ataxia with slow saccades.
abstract: Ataxia is a symptom of cerebellar dysfunction. Slowly progressive ataxia, dysarthria in an adult with a positive family history suggests an inherited cerebellar ataxia. We present an adult with gradually progressive ataxia and slow saccades. There was history of similar illness in his son. Genetic testing for spinocerebellar ataxia 2 was positive. We discuss the various inherited ataxias, causes of acute, progressive ataxia syndromes, episodic ataxias and ataxia associated with other neurological signs like peripheral neuropathy, pyramidal features, movement disorders and cognitive decline.
authors.affiliation: Department of Neurology, Topiwala National Medical College, B. Y. L. Nair Hospital, Dr. A. L. Nair Road, Mumbai Central, Mumbai, India.
authors.forename: R T
authors.initials: RT
authors.lastname: Chakor
authors.forename: H
authors.initials: H
authors.lastname: Bharote
mesh_terms: D000328:Adult; D004401:Dysarthria / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009154:Mutation; D016133:Polymerase Chain Reaction; D012438:Saccades / Q000235:genetics*; D020754:Spinocerebellar Ataxias / Q000151:congenital* / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology