title: Palladium-catalyzed ortho-CH-bond oxygenation of aromatic ketones.
abstract: A palladium-catalyzed C((sp2))-H bond oxygenation reaction is described. This protocol represents the first example of a C-H bond cleavage/C-O bond formation sequence, by employing a ketone moiety as the directing group. With this new catalytic method, a variety of ortho-acylphenols can be easily accessed from arylketones.
authors.affiliation: State Key Laboratory of Chiroscience and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
authors.forename: Pui Ying
authors.initials: PY
authors.lastname: Choy
authors.forename: Fuk Yee
authors.initials: FY
authors.lastname: Kwong
mesh_terms: D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D010636:Phenols / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D007659:Ketones; D010636:Phenols; D010165:Palladium