title: Distribution of contrast medium epidurally injected at thoracic and lumbar vertebral segments.
abstract: The epidural distribution of iohexol (0.2 ml/kg) administered at thoracic vertebrae (Thoracic group) and lumbar vertebrae (Lumbar group) was compared by computed tomographic (CT) epidurography in dogs. The total spread of iohexol was similar between the 2 groups upon reaching a similar cranial level. The maximal CT values were higher at the C7/T1 and T4/T5 levels in Thoracic group, but they were higher at the T13/L1 and L4/L5 levels in Lumbar group (P<0.05). This result suggests that the distribution pattern of the drug administered epidurally at thoracic vertebrae and lumbar vertebrae is different in dogs.
authors.affiliation: Laboratory of Veterinary Emergency Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
authors.forename: Di
authors.initials: D
authors.lastname: Zhang
authors.forename: Reina
authors.initials: R
authors.lastname: Fujiwara
authors.forename: Toshie
authors.initials: T
authors.lastname: Iseri
authors.forename: Shotaro
authors.initials: S
authors.lastname: Nagahama
authors.forename: Kei
authors.initials: K
authors.lastname: Kakishima
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kamata
authors.forename: Manabu
authors.initials: M
authors.lastname: Mochizuki
authors.forename: Takayuki
authors.initials: T
authors.lastname: Nakagawa
authors.forename: Nobuo
authors.initials: N
authors.lastname: Sasaki
authors.forename: Ryohei
authors.initials: R
authors.lastname: Nishimura
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D004285:Dogs; D007268:Injections, Epidural / Q000662:veterinary; D007472:Iohexol / Q000008:administration & dosage* / Q000493:pharmacokinetics*; D008159:Lumbar Vertebrae; D013904:Thoracic Vertebrae; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D007472:Iohexol