title: Shell technique using a rigid resorbable barrier system for localized alveolar ridge augmentation.
abstract: OBJECTIVE
  To assess the safety and efficacy of a rigid synthetic barrier system in a shell technique for localized alveolar ridge augmentation.
  
  
  METHODS
  Saddle-type defects (n = 4 each) were prepared in the lower jaws of six fox hounds. At two defects, the outer contours were reconstructed using polylactic acid (D and L isomers) (PDDL) pins welded to PDDL plates by ultrasound vibration and the defect area filled using either a natural bone mineral (NBM) or NBM + autogenous bone (AB) and covered by a native collagen membrane (CM). While the third defect was augmented using NBM+AB+CM, the fourth site was left untreated. At 14 weeks, dissected blocks were processed for histomorphometrical analysis [e.g., augmented area (AA)].
  
  
  RESULTS
  AA values (median in mm(2)) were significantly increased in all guided bone regeneration (GBR) groups [NBM+PDDL+CM (19.74) > NBM+AB+PDDL+CM (16.98) > NBM+AB+CM (16.66)] when compared with the untreated control sites (7.34). Histological analysis has pointed, in the absence of any foreign-body reactions, to biodegradation of both PDDL plates/pins and CM.
  
  
  CONCLUSIONS
  (i) All GBR procedures investigated equally supported bone regeneration, (ii) the application of PDDL+CM may be associated with increased mineralized tissue MT and subsequently AA values than CM alone, and (iii) AB may not improve healing at NBM+PDDL+CM-treated sites.
authors.affiliation: Department of Oral and Maxillofacial Surgery, George-Augusta-University, Göttingen, Germany.
authors.forename: Gerhard
authors.initials: G
authors.lastname: Iglhaut
authors.forename: Frank
authors.initials: F
authors.lastname: Schwarz
authors.forename: Marcel
authors.initials: M
authors.lastname: Gründel
authors.forename: Ilja
authors.initials: I
authors.lastname: Mihatovic
authors.forename: Jürgen
authors.initials: J
authors.lastname: Becker
authors.forename: Henning
authors.initials: H
authors.lastname: Schliephake
mesh_terms: D020341:Absorbable Implants; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D000818:Animals; D016025:Bone Transplantation; D004285:Dogs; D016557:Guided Tissue Regeneration, Periodontal; D019344:Lactic Acid; D011091:Polyesters; D011108:Polymers; D014081:Tooth Extraction; D014182:Transplantation, Autologous; D014945:Wound Healing
chemical_list: D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide)
keywords: alveolar ridge defect; animal study; barrier membranes; bone substitutes; guided bone regeneration