title: Anti-S antibodies: an unusual cause of haemolytic disease of the fetus and newborn (HDFN).
abstract: We report a case of haemolytic disease of the fetus and newborn due to anti-S antibodies. Baby G was born by emergency caesarean section at 35 weeks due to reduced fetal movement. Prior to delivery, antenatal screening revealed the mother's blood group was AB rhesus positive with anti-S antibody titres. The baby was pale but non-hydropic at birth with hepatosplenomegaly. Haemoglobin at birth was 5.23 g/dl and serum bilirubin 138 µmol/l. The baby required phototherapy, γ-globulin infusion and exchange transfusion with post-transfusion complications.
authors.affiliation: Department of Paediatrics, Cavan General Hospital, Cavan, Ireland. docpitan@yahoo.co.uk
authors.forename: Christopher
authors.initials: C
authors.lastname: Pitan
authors.forename: Azhar
authors.initials: A
authors.lastname: Syed
authors.forename: W
authors.initials: W
authors.lastname: Murphy
authors.forename: Oluwafemi
authors.initials: O
authors.lastname: Akinlabi
authors.forename: Alan
authors.initials: A
authors.lastname: Finan
mesh_terms: D001323:Autoantibodies / Q000276:immunology*; D004899:Erythroblastosis, Fetal / Q000276:immunology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D017293:Protein S / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D017293:Protein S