title: Evaluation of inhaler technique and patient satisfaction with fixed-combination budesonide/formoterol dry-powder inhaler in chronic obstructive pulmonary disease (COPD): data on real-life clinical practice in Turkey.
abstract: BACKGROUND
  The present study was designed to evaluate inhaler techniques and patient satisfaction with fixed-combination budesonide/formoterol dry-powder inhaler chronic obstructive pulmonary disease (COPD) in Turkey in real-life clinical practice.
  
  
  METHODS
  A total of 442 patients with COPD [mean (SD) age: 63.2 (10.6) years, 76.5% were males] were included in this cross-sectional study conducted at 25 outpatient clinics across Turkey. Data on socio-demographic characteristics, characteristics of COPD, inhaler technique and satisfaction with dry-powder inhaler were recorded at a single crosssectional visit performed at the study enrolment.
  
  
  RESULTS
  Patients were characterized by prominence of moderate to severe (78.1%) COPD, high rate of regular use of overall COPD medications (89.4%) and Turbuhaler® for an average of 33.7 months, predominance of males (76.5%), primary education (85.7%), urban location (68.3), ex-smokers (61.1%) and spending time outdoors for ≥ 4 hour/day (62.0%). Use of correct techniques was evident in majority of patients (≥ 94%), whereas inhalation maneuvers including breathing out gently away from mouthpiece without blowing into it (71.9%) and holding the breath for 5-10 seconds (78.3%) were performed correctly by lesser percent of patients especially in the older group (≥ 65 years, p< 0.05). Overall percent of patients with the feeling that she/he used the inhaler very/fairly correctly was 73.3%, while 86% of patients identified that they were very/fairly satisfied with the inhaler, irrespective of age and educational status.
  
  
  CONCLUSIONS
  In conclusion, our findings revealed the majority of patients are able to use Turbuhaler® correctly regardless of the educational status, while older age was associated with higher rate of errors in inhalation maneuvers in the real clinical practice in Turkey. Majority of our patients identified Turbuhaler® to be very/fairly convenient regarding ease of use, portability, and usability with an overall self-confidence in using the inhaler correctly among 73% and the satisfaction rate of 86%; irrespective of age and educational level.
authors.affiliation: Gazi University Faculty of Medicine, Ankara, Turkey. canozturk.gazi@gmail.com
authors.forename: Can
authors.initials: C
authors.lastname: Öztürk
authors.forename: Akın
authors.initials: A
authors.lastname: Kaya
authors.forename: Cahit
authors.initials: C
authors.lastname: Bilgin
authors.forename: Leyla
authors.initials: L
authors.lastname: Yücesoy
authors.forename: Belgin
authors.initials: B
authors.lastname: İkidağ
authors.forename: Mustafa
authors.initials: M
authors.lastname: Demirel
authors.forename: Şeyma
authors.initials: Ş
authors.lastname: Başlılar
authors.forename: Bengü
authors.initials: B
authors.lastname: Şaylan
authors.forename: Tuncer
authors.initials: T
authors.lastname: Senol
authors.forename: Semih
authors.initials: S
authors.lastname: Ağanoğlu
authors.forename: Gonca
authors.initials: G
authors.lastname: Can
authors.forename: Mustafa Ilgaz
authors.initials: MI
authors.lastname: Doğrul
authors.forename: Murat
authors.initials: M
authors.lastname: Çam
authors.forename: Nezaket
authors.initials: N
authors.lastname: Erdoğan
authors.forename: Özgür
authors.initials: Ö
authors.lastname: Batum
authors.forename: Muzaffer Onur
authors.initials: MO
authors.lastname: Turan
authors.forename: Cahit
authors.initials: C
authors.lastname: Demir
authors.forename: Şerife
authors.initials: Ş
authors.lastname: Torun
authors.forename: Murat
authors.initials: M
authors.lastname: Cirit
authors.forename: Mehmethan
authors.initials: M
authors.lastname: Turan
authors.forename: Arif
authors.initials: A
authors.lastname: Keleşoğlu
authors.forename: Savaş
authors.initials: S
authors.lastname: Yaşar
authors.forename: Öznur
authors.initials: Ö
authors.lastname: Uzunay
authors.forename: Kevser
authors.initials: K
authors.lastname: Melek
authors.forename: Osman
authors.initials: O
authors.lastname: Altıparmak
mesh_terms: D000280:Administration, Inhalation; D000367:Age Factors; D000368:Aged; D001993:Bronchodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D019819:Budesonide / Q000008:administration & dosage / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D004338:Drug Combinations; D058995:Dry Powder Inhalers / Q000295:instrumentation / Q000379:methods*; D004522:Educational Status; D004983:Ethanolamines / Q000008:administration & dosage / Q000627:therapeutic use; D000068759:Formoterol Fumarate; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D029424:Pulmonary Disease, Chronic Obstructive / Q000188:drug therapy*; D016896:Treatment Outcome; D014421:Turkey
chemical_list: D001993:Bronchodilator Agents; D004338:Drug Combinations; D004983:Ethanolamines; D019819:Budesonide; D000068759:Formoterol Fumarate