title: An analysis of "no effect of insulin pen with memory function on glycemic control in a patient cohort with poorly controlled type 1 diabetes: a randomized open-label study".
abstract: Missing meal bolus and nonadherence is an important barrier to achieving glycemic goals in type 1 diabetes (T1DM). In this issue of Journal of Diabetes Science and Technology, Danne and coauthors reported the results of a 24-week randomized-controlled study designed to evaluate if using an insulin pen with memory function, the HumaPen® Memoir™, might improve injection compliance and, therefore, overall glycemic control in T1DM. Patients treated with the pen device with memory function improved, albeit nonsignificantly, their mean HbA1c by 0.43%. Among the reasons to justify why this study was not positive, the most important is the high proportion of adult patients included in the study (87.9%)-children and adolescents being under-represented. I am convinced that pen devices with memory function might be helpful for forgetful patients (children, adolescents), as suggested in another recent study.
authors.affiliation: Diabetes Reference Unit, Endocrinology and Nutrition Department, Clinic University Hospital of Valencia and Department of Medicine, University of Valencia, Valencia, Spain.
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Ampudia-Blasco
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D062905:Central Venous Catheters; D005260:Female; D006801:Humans; D008297:Male; D017551:Microdialysis / Q000295:instrumentation* / Q000379:methods*; D008991:Monitoring, Physiologic / Q000295:instrumentation* / Q000379:methods*
chemical_list: D001786:Blood Glucose