title: Stereoselective synthesis of fused spiroindolines via tandem Mannich/intramolecular aminal formation.
abstract: A novel tandem Mannich/intramolecular aminal formation between tryptamines and salicylaldehydes was reported. This strategy provides a promising approach for the stereoselective synthesis of a range of complex fused spiroindolines, which bear a highly congested contiguous spiro quaternary center and two tertiary stereocenters, in a highly economical and effective fashion.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu 730000, People's Republic of China.
authors.forename: Juan
authors.initials: J
authors.lastname: Yang
authors.forename: Xingang
authors.initials: X
authors.lastname: Xie
authors.forename: Zhengshen
authors.initials: Z
authors.lastname: Wang
authors.forename: Ruoming
authors.initials: R
authors.lastname: Mei
authors.forename: Huaiji
authors.initials: H
authors.lastname: Zheng
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Wang
authors.forename: Ling
authors.initials: L
authors.lastname: Zhang
authors.forename: Jing
authors.initials: J
authors.lastname: Qi
authors.forename: Xuegong
authors.initials: X
authors.lastname: She