title: [Clear cells cervical adenocarcinoma in a girl no exposed to dietiletilbestrol].
abstract: BACKGROUND
  the clear cell adenocarcinoma (CCA) in cervix is a rare disease. It represents only 2 to 7 % of whole adecocarcinomas of cervix. Its histological pattern seems identical to their counterparts elsewhere in the female genital tract, including the vagina, endometrial and ovary. The CCA is constituted by cells with a clear cytoplasm in tack that are arranged in a solid pattern, tubu-locystic, papillary, or mixed.
  
  
  METHODS
  an eleven year old girl with sporadic and intermittent transvaginal bleeding, and who felt in severe anemia due to hiperpolimenorrea treated with athinyl estradiol deso-gestrel was attended. She had not history of exposition in utero to diethyletilbestrol. Hysteroscopy showed an ectocervical exophytic lesion in a barrel of 7 × 3 × 3 cm, located predominantly in the posterior lip. A frozen section of the lesion was reported as a poorly differentiated malignant tumor compatible with cervical carcinoma. She underwent to simple trachelectomy.
  
  
  CONCLUSIONS
  diagnostic difficulty was the age of the patient and the lack exposition in utero to DES, the differential diagnosis included the age group tumors and rhabdomyosarcoma botryoides and extragonadal endodermic origen with papillary and reticular pattern. Another was a metastatic CCA.
authors.affiliation: Departamento de Patología, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Distrito Federal, Mexico. ely_rom@hotmail.com
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Romero-Durán
authors.forename: Neyda Cecilia
authors.initials: NC
authors.lastname: Chávez-Bravo
authors.forename: Antonio Severo
authors.initials: AS
authors.lastname: García-Rodríguez
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000473:pathology; D002648:Child; D004054:Diethylstilbestrol; D005260:Female; D006801:Humans; D002583:Uterine Cervical Neoplasms / Q000473:pathology
chemical_list: D004054:Diethylstilbestrol