title: Application of chip-based flow cytometry for amphotericin B and fluconazole susceptibility testing on Candida strains.
abstract: Chip-based flow cytometry is a rather new method that offers an easy, fast opportunity for examination of yeasts, such as Candida cells. In our study cell-chip technology was tested with ATCC Candida strains to determine their viability and susceptibility against antifungal agents, amphotericin B and fluconazole. We found this technology to be suitable for the detection of Candida cells, for the differentiation between dead and living cells, and for the determination of amphotericin B and fluconazole susceptibility of different Candida strains (Bouquet et al., Mycoses 55:e90-e96, 2012).
authors.affiliation: Department of Analytical and Environmental Chemistry, Faculty of Sciences, University of Pécs, Pécs, Hungary. bouquetorsi@gmail.com
authors.forename: Orsolya
authors.initials: O
authors.lastname: Bouquet
authors.forename: Béla
authors.initials: B
authors.lastname: Kocsis
authors.forename: Ferenc
authors.initials: F
authors.lastname: Kilár
authors.forename: Ildikó
authors.initials: I
authors.lastname: Kustos
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects*; D025141:Drug Resistance, Fungal; D005434:Flow Cytometry / Q000379:methods*; D015725:Fluconazole / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D046208:Microchip Analytical Procedures / Q000379:methods*
chemical_list: D000666:Amphotericin B; D015725:Fluconazole