title: First Pillcam Colon 2 capsule images of Whipple's disease: Case report and review of the literature.
abstract: Whipple's disease is a rare chronic systemic infection determined by the Gram-positive bacillus Tropheryma whipplei. The infection usually mainly involves the small bowel, but sometimes other organs are affected as well. Since the current standard clinical and biological tests are nonspecific, diagnosis is very difficult and relies on histopathology. Here we present the case of a 52-year-old man with chronic diarrhea and weight loss whose symptoms had been evolving for 2 years and whose diagnosis came unexpectedly after capsule examination. Diagnosis was confirmed by the histopathologic examination of endoscopic biopsy samples, and treatment with co-trimoxazole resulted in remission of symptoms. We present the first images of Whipple's disease obtained with the Pillcam Colon 2 video capsule system.
authors.affiliation: Bogdan Radu Mateescu, Andreea Bengus, Madalina Marinescu, Department of Gastroenterology, Colentina Hospital, Bucharest 50098, Romania.
authors.forename: Bogdan Radu
authors.initials: BR
authors.lastname: Mateescu
authors.forename: Andreea
authors.initials: A
authors.lastname: Bengus
authors.forename: Madalina
authors.initials: M
authors.lastname: Marinescu
authors.forename: Florica
authors.initials: F
authors.lastname: Staniceanu
authors.forename: Gianina
authors.initials: G
authors.lastname: Micu
authors.forename: Lucian
authors.initials: L
authors.lastname: Negreanu
keywords: Capsule endoscopy; Malabsorption; Pillcam Colon 2; Whipple’s disease