title: Multiple gastrointestinal stromal tumors and pheochromocytoma in a patient with von Recklinghausen's disease.
abstract: BACKGROUND
  Neurofibromatosis type 1 is a genetic disease characterized by neoplastic and non neoplastic disorders involving tissues of neuroectodermal and mesenchymal origin. Herein, we present a case with von Recklinghausen's disease, right adrenal heochromocytoma and multiple gastrointestinal stromal tumors.
  
  
  METHODS
  A forty-eight year old male patient was admitted to our Emergency Department with melena. His physical examination revealed multiple neurofibromas all over the skin, kyphosis, multiple cafe au lait spots and Lisch nodules on the eye and, melena on digital rectal examination. Abdominal computerized tomography scan showed a mass on right adrenal gland and multiple soft tissue mass lesions between distal part of pancreas and small bowel. Adrenal mass was determined as a pheochromocytoma and small bowel lesions were verified as stromal tumors.
  
  
  CONCLUSIONS
  In patients with NF1, pheochromocytomas and GISTs are well known neoplasms seen with increased incidence than the general population.
  
  
  CONCLUSIONS
  In patients with NF1, any symptoms with other systems should be managed carefully for underlying malignity.
authors.affiliation: Istanbul University, Istanbul Medical Faculty, General Surgery Department, Capa, Istanbul, Turkey. Electronic address: drbeyza@hotmail.com.
authors.forename: Beyza
authors.initials: B
authors.lastname: Ozcinar
authors.forename: Nihat
authors.initials: N
authors.lastname: Aksakal
authors.forename: Orhan
authors.initials: O
authors.lastname: Agcaoglu
authors.forename: Mustafa
authors.initials: M
authors.lastname: Tukenmez
authors.forename: Ibrahim A
authors.initials: IA
authors.lastname: Ozemir
authors.forename: Umut
authors.initials: U
authors.lastname: Barbaros
authors.forename: Nese
authors.initials: N
authors.lastname: Colak
authors.forename: Yesim
authors.initials: Y
authors.lastname: Erbil