title: Classification using NMR-based metabolomics of Sophora flavescens grown in Japan and China.
abstract: We demonstrate that NMR-based metabolomics can be used to identify the country of growth (Japan or China) of Sophora flavescens plants. Principle Component Analysis (PCA) conducted on extracts of S. flavescens grown in China provided data distinct from that of extracts of plants grown in Japan. Loading plot analysis showed signals characteristic of Japanese S. flavescens. NMR analyses showed these signals to be due to kurarinol (1) and kushenol H (2). These compounds were confirmed by HPLC analysis to be distinctive markers for Japanese S. flavescens.
authors.affiliation: Department of Pharmacognosy and Natural Medicines, Faculty of Pharmaceutical Sciences, Josai University, 1-1 Keyakidai, Sakado, Saitama 350-0295, Japan.
authors.forename: Ryuichiro
authors.initials: R
authors.lastname: Suzuki
authors.forename: Yuriko
authors.initials: Y
authors.lastname: Ikeda
authors.forename: Akari
authors.initials: A
authors.lastname: Yamamoto
authors.forename: Toyoe
authors.initials: T
authors.lastname: Saima
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Fujita
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Fukuda
authors.forename: Eriko
authors.initials: E
authors.lastname: Fukuda
authors.forename: Masaki
authors.initials: M
authors.lastname: Baba
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Okada
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Shirataki
mesh_terms: D002681:China; D007564:Japan; D009682:Magnetic Resonance Spectroscopy; D055442:Metabolome; D025341:Principal Component Analysis; D029909:Sophora / Q000145:classification / Q000378:metabolism*