title: Relationship between dyslipidaemia and semen quality and serum sex hormone levels: an infertility study of 167 Japanese patients.
abstract: A prospective study was performed in the Reproduction Center of Ichikawa General Hospital (Chiba, Japan) to assess the relationship between dyslipidaemia and sperm quality and serum hormone levels in male patients in Japan. The semen parameters and blood samples were assessed in relation to several variables, including body mass index (BMI) and serum triglyceride (TG) levels. Between 2011 and 2012, 167 male partners of infertile couples aged 22-46 years (mean: 36.5 years) were referred to the reproduction centre. In total, 66 patients (39.5%) had hypertriglyceridaemia (TG level ≥ 150 mg dl(-1) ). There was no significant relationship between serum TG levels and sperm concentration or motility; however, the serum TG level was positively associated with the sperm morphological traits. Furthermore, the serum levels of glutamic oxaloacetic transaminase and glutamic pyruvic transaminase were associated with the serum TG levels. By contrast, a negative relationship between serum testosterone and TG levels was discovered.
authors.affiliation: Department of Urology, Ichikawa General Hospital, Tokyo Dental College, Ichikawa, Chiba, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Hagiuda
authors.forename: H
authors.initials: H
authors.lastname: Ishikawa
authors.forename: T
authors.initials: T
authors.lastname: Furuuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Hanawa
authors.forename: K
authors.initials: K
authors.lastname: Marumo
mesh_terms: D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D015992:Body Mass Index; D050171:Dyslipidemias / Q000097:blood / Q000503:physiopathology*; D004958:Estradiol / Q000097:blood; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D007248:Infertility, Male / Q000097:blood* / Q000453:epidemiology; D007564:Japan / Q000453:epidemiology; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D055101:Semen Analysis; D013739:Testosterone / Q000097:blood; D014280:Triglycerides / Q000097:blood
chemical_list: D012739:Gonadal Steroid Hormones; D014280:Triglycerides; D013739:Testosterone; D004958:Estradiol; D007986:Luteinizing Hormone; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
keywords: Body mass index; obesity; sex hormone; sperm quality; triglyceride