title: [Cost-utility analysis of comprehensive intervention on epilepsy].
abstract: OBJECTIVE
  To discuss the cost-utility regarding the effect of comprehensive intervention program on epilepsy.
  
  
  METHODS
  874 cases with epilepsy were investigated in 9 pilot sites in Henan province. Cost of epilepsy comprehensive intervention was calculated based on the research projects of epilepsy prevention and management of rural areas. Disability-adjusted life year (DALY) and quality adjusted life year (QALY) were used as utility index for cost-utility analysis.
  
  
  RESULTS
  Of the 874 cases, 8.58 DALY was lost and 27.95 QALY was obtained per capita in the intervention group (422 cases). The costs per QALY and DALY obtained were 2454.10 and 7995.40 Yuan, respectively. Relative to the non-intervention control group (452 cases), the costs for QALY obtained by the intervention group had reduced. The investment would reduce 21 735.10 Yuan when each additional DALY was saved.
  
  
  CONCLUSIONS
  Epilepsy caused serious economic burden to the society, families and the patients themselves. Comprehensive intervention program could reduce the economic burden of the disease thus yielding high cost-benefit. This program was deserved to be promoted.
authors.affiliation: Henan Provincial Center for Disease Control and Prevention, Zhengzhou 450000, China. sinary007@163.com
authors.forename: Liang
authors.initials: L
authors.lastname: Chang
authors.forename: Jing
authors.initials: J
authors.lastname: Chang
authors.forename: Shi-xian
authors.initials: SX
authors.lastname: Feng
authors.forename: Gang
authors.initials: G
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002681:China; D017281:Cost of Illness; D003362:Cost-Benefit Analysis; D004827:Epilepsy / Q000191:economics* / Q000517:prevention & control*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019057:Quality-Adjusted Life Years; D055815:Young Adult