title: Second sphere control of redox catalysis: selective reduction of O2 to O2- or H2O by an iron porphyrin catalyst.
abstract: "Click" reaction has been utilized to synthesize porphyrin ligands possessing distal superstructures functionalized with ferrocenes, carboxylic acid esters, and phenols. Both structural and spectroscopic evidence indicate that hydrogen bonding interaction between the triazole residues resulting from the "click" reaction promotes axial ligand binding into the sterically demanding distal pocket in preference to the open proximal side. An iron porphyrin complex with four ferrocene groups is found to bind O(2) and quantitatively reduce it by one electron to O(2)(-) in apolar organic solvents. However the same complex electro-catalytically reduces O(2) by four electrons to H(2)O in aqueous medium under fast, moderate, and slow electron fluxes. This selectivity for O(2) reduction is governed by the reduction potential of the electron transfer site (i.e., ferrocene) which in turn is governed by the solvent. This catalyst mimics control of catalysis of an enzyme active site by a second sphere electron transfer residue which is often encountered in naturally occurring metallo-enzymes.
authors.affiliation: Department of Inorganic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India.
authors.forename: Subhra
authors.initials: S
authors.lastname: Samanta
authors.forename: Kaustuv
authors.initials: K
authors.lastname: Mittra
authors.forename: Kushal
authors.initials: K
authors.lastname: Sengupta
authors.forename: Sudipta
authors.initials: S
authors.lastname: Chatterjee
authors.forename: Abhishek
authors.initials: A
authors.lastname: Dey
mesh_terms: D002384:Catalysis; D058085:Iron Compounds / Q000737:chemistry*; D008665:Metalloporphyrins / Q000138:chemical synthesis / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D058085:Iron Compounds; D008665:Metalloporphyrins; D014867:Water; D010100:Oxygen