title: Tracing superior longitudinal fasciculus connectivity in the human brain using high resolution diffusion tensor tractography.
abstract: The major language pathways such as superior longitudinal fasciculus (SLF) pathways have been outlined by experimental and diffusion tensor imaging (DTI) studies. The SLF I and some of the superior parietal lobule connections of the SLF pathways have not been depicted by prior DTI studies due to the lack of imaging sensitivity and adequate spatial resolution. In the current study, the trajectory of the SLF fibers has been delineated on five healthy human subjects using diffusion tensor tractography on a 3.0-T scanner at high spatial resolution. We also demonstrate for the first time the trajectory and connectivity of the SLF fibers in relation to other language pathways as well as the superior parietal lobule connections of the language circuit using high spatial resolution DTI in the healthy adult human brain.
authors.affiliation: Department of Radiology, Cooper University Hospital, UMDNJ, Camden, NJ, USA.
authors.forename: Arash
authors.initials: A
authors.lastname: Kamali
authors.forename: Adam E
authors.initials: AE
authors.lastname: Flanders
authors.forename: Joshua
authors.initials: J
authors.lastname: Brody
authors.forename: Jill V
authors.initials: JV
authors.lastname: Hunter
authors.forename: Khader M
authors.initials: KM
authors.lastname: Hasan
mesh_terms: D000328:Adult; D001921:Brain / Q000033:anatomy & histology*; D001931:Brain Mapping; D056324:Diffusion Tensor Imaging; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008297:Male; D009413:Nerve Fibers, Myelinated / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology*; D055815:Young Adult