title: Analysis of 16 phthalic acid esters in food simulants from plastic food contact materials by LC-ESI-MS/MS.
abstract: An RP LC-ESI-MS/MS method for the determination of the migration of 16 primary phthalic acid esters from plastic samples has been developed using distilled water, 3% acetic acid, 10% alcohol, and olive oil as food simulants. Detection limits were 1.6-18.5 μg/kg in distilled water, 1.4-17.3 μg/kg in 3% acetic acid, 1.4-19.2 μg/kg in 10% alcohol, and 31.9-390.8 μg/kg in olive oil. The RSDs were in the range of 0.07-11.28%. The real plastic products inspection showed that only few analyzed samples were phthalates contaminated. Bis-2-ethylhexyl ester and dibutyl phthalate were the common items migrated from the plastic products into food and feeds, but the migration concentrations were far below the limits set by European Union (1.5 mg/kg for bis-2-ethylhexyl ester and 0.3 mg/kg for dibutyl phthalate).
authors.affiliation: Technical Centre of Fujian Entry-Exit Inspection and Quarantine Bureau, Fuzhou, P R China. lxjciq@hotmail.com
authors.forename: Xiaojing
authors.initials: X
authors.lastname: Li
authors.forename: Wenming
authors.initials: W
authors.lastname: Xiong
authors.forename: Hua
authors.initials: H
authors.lastname: Lin
authors.forename: Liyang
authors.initials: L
authors.lastname: Zhuo
authors.forename: Shuiyuan
authors.initials: S
authors.lastname: Lv
authors.forename: Xi
authors.initials: X
authors.lastname: Tang
authors.forename: Minshi
authors.initials: M
authors.lastname: Chen
authors.forename: Zhexiang
authors.initials: Z
authors.lastname: Zou
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Lin
authors.forename: Bin
authors.initials: B
authors.lastname: Qiu
authors.forename: Guonan
authors.initials: G
authors.lastname: Chen
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D004952:Esters / Q000737:chemistry*; D005506:Food Contamination / Q000032:analysis*; D018857:Food Packaging / Q000295:instrumentation*; D000069463:Olive Oil; D010795:Phthalic Acids / Q000737:chemistry*; D010938:Plant Oils / Q000032:analysis*; D010969:Plastics / Q000032:analysis*; D053719:Tandem Mass Spectrometry / Q000379:methods*
chemical_list: D004952:Esters; D000069463:Olive Oil; D010795:Phthalic Acids; D010938:Plant Oils; D010969:Plastics