title: A gallbladder tumor revealing metastatic clear cell renal carcinoma: report of case and review of literature.
abstract: Metastatic renal cell carcinoma in the gallbladder is extremely rare, with reported frequencies of less than 0.6% in large autopsy reviews. Only 40 cases were reported in the literature. We report a first case of gallbladder polypoid tumor revealing metastatic clear cell renal cell carcinoma, which demonstrates the importance of radiological tests, histology and immunohistochemistry when making a definitive diagnosis. These examinations also allow differentiating metastatic clear cell renal cell carcinoma from other polypoid lesions in the gallbladder with clear cell morphology. Cholecystectomy should be performed to obtain a definitive diagnosis and to improve survival in case of solitary metastatic renal cell carcinoma.
  The virtual slides' for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/8956897238238989
authors.affiliation: Department of Pathology, Ibn Sina Univesity Hospital, Rabat, Morocco. merighaouti@live.fr
authors.forename: Merieme
authors.initials: M
authors.lastname: Ghaouti
authors.forename: Kaoutar
authors.initials: K
authors.lastname: Znati
authors.forename: Ahmed
authors.initials: A
authors.lastname: Jahid
authors.forename: Fouad
authors.initials: F
authors.lastname: Zouaidia
authors.forename: Zakiya
authors.initials: Z
authors.lastname: Bernoussi
authors.forename: Youssef
authors.initials: Y
authors.lastname: El Fakir
authors.forename: Najat
authors.initials: N
authors.lastname: Mahassini
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D002292:Carcinoma, Renal Cell / Q000737:chemistry / Q000556:secondary* / Q000601:surgery; D002763:Cholecystectomy; D003937:Diagnosis, Differential; D005260:Female; D005706:Gallbladder Neoplasms / Q000737:chemistry / Q000556:secondary* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D009392:Nephrectomy; D011237:Predictive Value of Tests; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor