title: Unified geometry and topology correction for cortical surface reconstruction with intrinsic reeb analysis.
abstract: A key challenge in the accurate reconstruction of cortical surfaces is the automated correction of geometric and topological outliers in tissue boundaries. Conventionally these two types of errors are handled separately. In this work, we propose a unified analysis framework for the joint correction of geometric and topological outliers in cortical reconstruction. Using the Reeb graph of intrinsically defined Laplace-Beltrami eigenfunctions, our method automatically locates spurious branches, handles and holes on tissue boundaries and corrects them with image information and geometric regularity derived from paired boundary evolutions. In our experiments, we demonstrate on 200 MR images from two datasets that our method is much faster and achieves better performance than FreeSurfer in population studies.
authors.affiliation: Lab. of Neuro Imaging, Dept. of Neurology, UCLA School of Medicine, Los Angeles, CA, USA.
authors.forename: Yonggang
authors.initials: Y
authors.lastname: Shi
authors.forename: Rongjie
authors.initials: R
authors.lastname: Lai
authors.forename: Arthur W
authors.initials: AW
authors.lastname: Toga
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D000544:Alzheimer Disease / Q000473:pathology*; D001185:Artificial Intelligence; D001921:Brain / Q000473:pathology; D001931:Brain Mapping / Q000379:methods; D002540:Cerebral Cortex / Q000473:pathology*; D016208:Databases, Factual; D003952:Diagnostic Imaging / Q000379:methods; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D008962:Models, Theoretical; D010363:Pattern Recognition, Automated / Q000379:methods; D015203:Reproducibility of Results