title: Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination.
abstract: OBJECTIVE
  To evaluate the success rate of a modified bleb needling technique in eyes with previous glaucoma surgery that had elevated intraocular pressure.
  
  
  METHODS
  A retrospective study of 24 eyes of 24 patients that underwent repeated bleb needling performed for failing and failed blebs on slit lamp with 5-fluorouracil (5-FU) injections on demand. This was performed after gonioscopic examination to define levels of filtration block.
  
  
  RESULTS
  There was significant reduction of mean IOP from 36.91 mmHg to 14.73 mmHg at the final follow-up (P < 0.001). The overall success rate was 92%.
  
  
  CONCLUSIONS
  Repeated needling with adjunctive 5-FU proved a highly effective, safe alternative to revive filtration surgery rather than another medication or surgery.
authors.affiliation: Ophthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
authors.forename: Mohammad A
authors.initials: MA
authors.lastname: Rashad
keywords: 5-FU; bleb; failure; gonioscopy; needling