title: Osteoarthritis in 2012: Parallel evolution of OA phenotypes and therapies.
abstract: 2012 has witnessed new developments in targeted therapies for osteoarthritis, and in ways to identify those patients who might benefit most from their application. Together, these advances could go some way to addressing the urgent need for disease-modifying treatments for this common disease.
authors.affiliation: Division of Musculoskeletal Disease, University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds LS7 4SA, UK. p.conaghan@leeds.ac.uk
authors.forename: Philip G
authors.initials: PG
authors.lastname: Conaghan
mesh_terms: D000818:Animals; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001853:Bone Marrow / Q000473:pathology; D002417:Cattle; D004195:Disease Models, Animal; D006801:Humans; D008279:Magnetic Resonance Imaging; D051379:Mice; D010003:Osteoarthritis / Q000188:drug therapy* / Q000473:pathology*; D010641:Phenotype; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D018501:Antirheumatic Agents; D014409:Tumor Necrosis Factor-alpha