title: Evaluation of risk factors for body weight increment in psoriatic patients on infliximab: a multicentre, cross-sectional study.
abstract: BACKGROUND
  A significant weight gain has been reported in patients with psoriasis treated with anti-tumour necrosis factor-alpha agents. Among these patients, there are contradictory results about risk factors for weight gain.
  
  
  OBJECTIVE
  Assessing risk factors for weight increment in psoriatic patients on infliximab (IFX).
  
  
  METHODS
  This study was a 4-month, non-interventional, cross-sectional, multicentre study on adults with psoriasis performed in 19 French dermatological centres. All the patients who received IFX for at least 1 year were prospectively included, with retrospective analysis of data. Impact of sex, age, severity of the disease, cardiovascular and metabolic comorbidities, and previous and simultaneous systemic treatments on weight changes, was analysed. Weight gain was defined as an increment of more than 2% of baseline weight.
  
  
  RESULTS
  Overall, 191 psoriatic patients (males: 68.6%; mean age: 46.9 years) were included. Mean weight gain was 1.6 kg (2.1%) after 1 year of IFX. Half (48.2%) suffered from a weight gain, and 9.9% from a weight increment of 10% or more. Baseline weight and Body Mass Index, and cardiovascular and metabolic comorbidities did not influence weight. Men (P=0.007) and patients with severe psoriasis (BSA, P=0.005) had a tendency to put on weight. Patients with a hospital dietary follow-up (P=0.01; OR=0.36 [0.16-0.79]) and patients on methotrexate (P=0.03; OR=0.41 [0.18-0.93]) during IFX treatment are thinner, in a multivariate analysis.
  
  
  CONCLUSIONS
  Severe weight increment is frequent on IFX treatment, mainly in men, and patients with severe psoriasis. Dietary follow-up or simultaneous use of methotrexate could limit this weight increment.
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: E
authors.initials: E
authors.lastname: Mahé
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: Z
authors.initials: Z
authors.lastname: Reguiai
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: H
authors.initials: H
authors.lastname: Barthelemy
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: N
authors.initials: N
authors.lastname: Quiles-Tsimaratos
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: G
authors.initials: G
authors.lastname: Chaby
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: C
authors.initials: C
authors.lastname: Girard
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: E
authors.initials: E
authors.lastname: Estève
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: F
authors.initials: F
authors.lastname: Maccari
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: V
authors.initials: V
authors.lastname: Descamps
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: J-L
authors.initials: JL
authors.lastname: Schmutz
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: E
authors.initials: E
authors.lastname: Begon
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: P
authors.initials: P
authors.lastname: Bravard
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: H
authors.initials: H
authors.lastname: Maillard
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: T
authors.initials: T
authors.lastname: Boyé
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: A
authors.initials: A
authors.lastname: Beauchet
authors.affiliation: Department of Dermatology, Hôpital Victor Dupouy, Argenteuil,Department of Dermatology, Centre Hospitalier Universitaire Robert Debré, Reims,Department of Dermatology, Centre Hospitalier d'Auxerre, Auxerre,Department of Dermatology, Hôpital Saint-Joseph, Marseille,Department of Dermatology, Hôpital Sud, Centre Hospitalier Universitaire d'Amiens, Picardie-Jules Verne University, Amiens,Department of Dermatology, Hôpital Saint-Eloi, Montpellier,Department of Dermatology, Centre Hospitalier Régional d'Orléans, Orléans,Department of Dermatology, Hôpital d'Instruction des Armées Bégin, Saint-Mandé,Department of Dermatology, Centre Hospitalier Universitaire Bichat-Claude Bernard, Paris 7 Diderot University, Assitance Publique-Hôpitaux de Paris, Paris,Department of Dermatology, Hôpitaux de Brabois, Vandœuvre les Nancy,Department of Dermatology, Centre Hospitalier de Pontoise, Pontoise,Department of Dermatology, Centre Hospitalier du Havres, Le Havres,Department of Dermatology, Centre Hospitalier du Mans, Le Mans,Department of Dermatology, Hôpital Sainte-Anne, Toulon, andDepartment of Public Health, Centre Hospitalier Universitaire Ambroise Paré, University of Versailles-Saint Quentin en Yvelines, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt, France.
authors.forename: M-L
authors.initials: ML
authors.lastname: Sigal
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D000911:Antibodies, Monoclonal / Q000009:adverse effects*; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000453:epidemiology; D004032:Diet; D050171:Dyslipidemias / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D000069285:Infliximab; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology*; D011565:Psoriasis / Q000188:drug therapy* / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors; D012907:Smoking / Q000453:epidemiology; D015430:Weight Gain / Q000187:drug effects*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000911:Antibodies, Monoclonal; D007166:Immunosuppressive Agents; D000069285:Infliximab; D008727:Methotrexate