title: Long-term voice results of injection with hyaluronic acid-dextranomere in unilateral vocal fold paralysis.
abstract: CONCLUSIONS
  Subjective and objective voice evaluation of patients injected with hyaluronic acid-dextranomere (HA-D) in the long term was not different from their preoperative values. HA-D injection does not provide an increase in the voice quality in the long term.
  
  
  OBJECTIVE
  This study was conducted to evaluate the long-term voice outcomes of injection with HA-D in patients with unilateral vocal fold paralysis (UVFP).
  
  
  METHODS
  Seventeen patients with UVFP underwent injection of HA-D. The patient group was composed of 13 women and 4 men with an age range of 34-56 years. The voice samples of patients were obtained before the injection and after the longest available follow-up. Long-term results were evaluated subjectively by the GRBAS scale and objectively by acoustic analysis.
  
  
  RESULTS
  The follow-up period was between 6 and 42 months. Fundamental frequency, jitter, and noise-to-harmonics ratio were decreased in the postoperative period. Shimmer was nearly the same. An increase in the S score and a decrease in R, B, and A scores were observed. Neither the GRBAS scale parameters nor the acoustic analysis results were statistically significantly different before injection and after long-term follow-up.
authors.affiliation: Ministry of Health, Ankara Training & Research Hospital, Department of Otolaryngology, Ankara, Turkey. drhoguz@gmail.com
authors.forename: Haldun
authors.initials: H
authors.lastname: Oguz
authors.forename: Munir
authors.initials: M
authors.lastname: Demirci
authors.forename: Necmi
authors.initials: N
authors.lastname: Arslan
authors.forename: Erhan
authors.initials: E
authors.lastname: Arslan
mesh_terms: D000328:Adult; D003911:Dextrans / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006820:Hyaluronic Acid / Q000627:therapeutic use*; D007267:Injections; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013061:Speech Acoustics; D013997:Time Factors; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D014833:Voice Quality
chemical_list: D003911:Dextrans; C487487:dextranomer-hyaluronic acid copolymer; D006820:Hyaluronic Acid