title: Malignancies of the spinal cord.
abstract: The management of intramedullary spinal cord tumors (IMSCT) is primarily concerned with the preservation of existing neurologic function. To this end, clinical scientists are continually seeking tools and techniques to improve the safety and efficacy of tumor resection and control. Further advances in safety and efficacy can be proposed at each phase of management, from pre-operative screening to post-treatment monitoring. Innovations within the areas of molecular biology and genetics, intraoperative imaging and stereotactic radiosurgery offer exciting new options to explore in the management of IMSCT. This section will review the pathophysiology and epidemiology of IMSCT and the state-of-the-art management before delving into the promising new tools and techniques for each phase of management.
authors.affiliation: Division of Neurosurgery, University of California San Diego Medical Center San Diego, California, USA. j.dawn.waters@gmail.com
authors.forename: J Dawn
authors.initials: JD
authors.lastname: Waters
authors.forename: Encarnacion Maria Navarro
authors.initials: EM
authors.lastname: Peran
authors.forename: Joseph
authors.initials: J
authors.lastname: Ciacci
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D015316:Genetic Therapy / Q000379:methods / Q000639:trends*; D023281:Genomics / Q000379:methods / Q000639:trends*; D006801:Humans; D010597:Pharmacogenetics / Q000379:methods / Q000639:trends; D016634:Radiosurgery / Q000379:methods / Q000639:trends*; D013120:Spinal Cord Neoplasms / Q000188:drug therapy / Q000235:genetics* / Q000601:surgery*
chemical_list: D000970:Antineoplastic Agents