title: WEB device for endovascular treatment of wide-neck bifurcation aneurysms.
abstract: OBJECTIVE
  The WEB is an intrasaccular flow disrupter dedicated to EVT of IA. We report our initial experience in a series of patients treated with this device.
  
  
  METHODS
  This prospective study was approved by the authors' ethical committees. Nineteen patients with 20 unruptured wide-neck bifurcation IAs were treated by WEB placement. Technical issues, immediate posttreatment angiographic findings, and clinical and imaging follow-up at 3, 6, and 12 months were assessed.
  
  
  RESULTS
  Failure of WEB placement occurred in 1 case because of unavailability of a suitably sized device. Embolization was successful in 18 patients with 19 IAs, and it required additional stent placement and/or coiling in 3 cases at the acute phase and in 1 case at follow-up. Two patients experienced a symptomatic complication, and 16 patients had normal neurologic examination findings at discharge. Immediate anatomic outcome showed 1 complete occlusion, 13 near-complete occlusions, and 5 incomplete occlusions. At follow-up, 17 patients had normal neurologic examination findings and 1 retained a hemiparesis. Angiographic controls were obtained in all patients (mean, 6 months), and they showed stable or improved results in all except 4 cases, including 2 complete occlusions, 15 near-complete occlusions, and 2 incomplete occlusions.
  
  
  CONCLUSIONS
  In this initial series of patients, EVT of wide-neck bifurcation IAa with the WEB was feasible. Further studies are needed to evaluate the indications, safety, and efficacy of this new technique.
authors.affiliation: Department of Neuroradiology, Erasme University Hospital, Brussels, Belgium. blubicz@ulb.ac.be
authors.forename: B
authors.initials: B
authors.lastname: Lubicz
authors.forename: B
authors.initials: B
authors.lastname: Mine
authors.forename: L
authors.initials: L
authors.lastname: Collignon
authors.forename: D
authors.initials: D
authors.lastname: Brisbois
authors.forename: G
authors.initials: G
authors.lastname: Duckwiler
authors.forename: C
authors.initials: C
authors.lastname: Strother
mesh_terms: D000328:Adult; D000368:Aged; D000497:Alloys / Q000627:therapeutic use; D002533:Cerebral Angiography; D002560:Cerebrovascular Circulation; D004621:Embolization, Therapeutic / Q000295:instrumentation* / Q000379:methods*; D057510:Endovascular Procedures / Q000295:instrumentation* / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015607:Stents; D013526:Surgical Mesh; D016896:Treatment Outcome
chemical_list: D000497:Alloys; C013616:nitinol