title: Biomarkers for ectopic pregnancy and pregnancy of unknown location.
abstract: Early pregnancy failure is the most common complication of pregnancy, and 1% to 2% of all pregnancies will be ectopic. As one of the leading causes of maternal morbidity and mortality, diagnosing ectopic pregnancy and determining the fate of a pregnancy of unknown location are of great clinical concern. Several serum and plasma biomarkers for ectopic pregnancy have been investigated independently and in combination. The following is a review of the state of biomarker discovery and development for ectopic pregnancy and pregnancy of unknown location.
authors.affiliation: Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
authors.forename: Suneeta
authors.initials: S
authors.lastname: Senapati
authors.forename: Kurt T
authors.initials: KT
authors.lastname: Barnhart
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D004717:Endometrium / Q000378:metabolism*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First / Q000378:metabolism*; D011271:Pregnancy, Ectopic / Q000175:diagnosis* / Q000378:metabolism*; D040901:Proteomics / Q000379:methods*
chemical_list: D015415:Biomarkers