title: Disseminated transmissible venereal tumour associated with Leishmaniasis in a dog.
abstract: This report addresses an atypical transmissible venereal tumour in an 8-year-old bitch that was pluriparous and seropositive for leishmaniasis. There were ascites and a serosanguineous discharge from the vulva, but no lesions on the external genital mucosa. An aspirate of the peritoneal fluid showed mononuclear round cells characteristic of transmissible venereal tumour (TVT). Exploratory laparotomy revealed light red, granulomatous structures in the peritoneum, omentum, spleen, liver and uterine horns. Cytological and histopathological tests confirmed the diagnosis of intra-abdominal TVT. Dissemination of the TVT to several organs inside the abdominal cavity probably resulted from immunosuppression caused by leishmaniasis, which favoured the presence and aggressiveness of TVT.
authors.affiliation: Department of Clinic, Surgery and Animal Reproduction, Faculty of Veterinary Medicine, UNESP - Univ Estadual Paulista, FMVA, Araçatuba, Brazil.
authors.forename: J T
authors.initials: JT
authors.lastname: Trevizan
authors.forename: J T
authors.initials: JT
authors.lastname: Carreira
authors.forename: N C
authors.initials: NC
authors.lastname: Souza
authors.forename: I R
authors.initials: IR
authors.lastname: Carvalho
authors.forename: P B C
authors.initials: PB
authors.lastname: Gomes
authors.forename: V M F
authors.initials: VM
authors.lastname: Lima
authors.forename: C M B
authors.initials: CM
authors.lastname: Orlandi
authors.forename: D B
authors.initials: DB
authors.lastname: Rozza
authors.forename: M B
authors.initials: MB
authors.lastname: Koivisto
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000209:etiology / Q000473:pathology*; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D007896:Leishmaniasis / Q000150:complications / Q000662:veterinary*; D014685:Venereal Tumors, Veterinary / Q000150:complications / Q000473:pathology*