title: HIV sero-prevalence among pregnant women in a resource constrained setting, South East Nigeria.
abstract: BACKGROUND
  HIV infection and AIDS is a public health problem worldwide, particularly affecting the populace in resource constrained settings like in sub-Saharan Africa. Women of reproductive age are most affected and infected with the disease.
  
  
  METHODS
  A descriptive study of pregnant women presenting for the first time at the obstetrics booking clinic of ESUTTH, Parklane from 1st April, 2009 to 31st March, 2010. Socio-demographic characteristics, sexual behavior, pregnancy history and STI related symptoms were obtained using already prepared proforma. HIV Screening test was conducted in a serial two step approach using Determine HIV test kits and Stat- Pak HIV kits after obtaining an informed consent. Discordant results were subjected to Western blot for confirmation. Data were entered and analyzed using Epi-info statistical software. P Value < 0.05 were assessed as statistically significant at 95% confidence interval.
  
  
  RESULTS
  A total of 1306 women were recruited, 66 women were HIV positive, giving a prevalence rate of 5.1%. Their mean age was 28.79 +/- 5.06 years. Majority of them were married (9%). The mean gestational age at booking was 26.2 +/- 6.8 weeks. Alcohol intake, history of 3 or more sexual partner in the last 5 years, abnormal vaginal discharge in the last 12 months, history of genital ulcer in last 12 month, had a statistically significant association with prevalence of HIV infection (p value < 0.005).
  
  
  CONCLUSIONS
  HIV infection prevalence rate in among antenatal attendants in Enugu is still high. A multi-sectoral approach is required for effective prevention and control of the disease to ensure achievement of Millennium development Goals 5&6.
authors.affiliation: Department of Obstetrics & Gynaecology, University of Nigeria Teaching Hospital, Ittuku-Ozalla Enugu state, Nigeria ezugwueuzebus@yahoo.com
authors.forename: E C
authors.initials: EC
authors.lastname: Ezugwu
authors.forename: P
authors.initials: P
authors.lastname: Agu
authors.forename: S A M
authors.initials: SA
authors.lastname: Ohayi
authors.forename: T C
authors.initials: TC
authors.lastname: Okeke
authors.forename: C C
authors.initials: CC
authors.lastname: Dim
authors.forename: S N
authors.initials: SN
authors.lastname: Obi
mesh_terms: D000328:Adult; D000428:Alcohol Drinking; D003906:Developing Countries; D005260:Female; D005831:Genital Diseases, Female / Q000453:epidemiology; D015658:HIV Infections / Q000453:epidemiology*; D015528:HIV Seroprevalence; D006801:Humans; D009549:Nigeria / Q000453:epidemiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D015995:Prevalence; D012725:Sexual Behavior; D014456:Ulcer / Q000453:epidemiology; D019522:Vaginal Discharge / Q000453:epidemiology; D055815:Young Adult