title: [Comparison of blood loss during total knee arthroplasty between haemophilic arthropathy and osteoarthritis].
abstract: OBJECTIVE
  To evaluate the amount of blood loss and the efficacy of clotting factor in controlling blood loss during total knee arthroplasty.
  
  
  METHODS
  The medical documents of 18 patients with haemophilic arthritis (HA) secondary to haemophilia A and 19 patients with osteoarthritis (OA) were retrospectively reviewed. Demographic data,functional and hematological test results,the amount of blood loss and transfusion,and complications were analyzed.
  
  
  RESULTS
  The median amounts of total and external blood loss were 2240 ml(1892-3415 ml) and 1326 ml(934-2256 ml)in the HA group, which were significant higher than those in the OA group [1746 ml(1259-2246 ml)and 846 ml (504-1217 ml), respectively]. The median amounts of external blood loss in the two groups were 680 ml(370-1330 ml)and 730 ml(200-1190 ml)and there was no significant difference(p=0.620). Moreover, more patients in the HA group required blood transfusion (84.2% vs. 47.4%), and more red cells were transfused per patient in the HA group (2.3 U vs. 0 U).
  
  
  CONCLUSIONS
  The total blood loss and hidden blood loss are higher in the HA patients than in OA patients during total knee arthroplasty, although the external blood loss is basically the same. Management with more clotting factor may decrease the blood loss in HA patients.
authors.affiliation: Department of Orthropaedic, PUMC Hospital, CAMS and PUMC, Beijing, China.
authors.forename: Ji-liang
authors.initials: JL
authors.lastname: Zhai
authors.forename: Xi-sheng
authors.initials: XS
authors.lastname: Weng
authors.forename: Hui-ming
authors.initials: HM
authors.lastname: Peng
authors.forename: Yan-yan
authors.initials: YY
authors.lastname: Bian
authors.forename: Tian-wen
authors.initials: TW
authors.lastname: Sun
authors.forename: Lei
authors.initials: L
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D000328:Adult; D001168:Arthritis / Q000209:etiology / Q000601:surgery*; D019645:Arthroplasty, Replacement, Knee; D006467:Hemophilia A / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery*; D019106:Postoperative Hemorrhage; D012189:Retrospective Studies; D055815:Young Adult