title: Replication of bone marrow differentiation niche: comparative evaluation of different three-dimensional matrices.
abstract: The comparative evaluation of different 3D matrices-Matrigel, Puramatrix, and inverted colloidal crystal (ICC) scaffolds-provides a perspective for studying the pathology and potential cures for many blood and bone marrow diseases, and further proves the significance of 3D cultures with direct cell-cell contacts for in vitro mimicry of the human stem cell niche.
authors.affiliation: Department of Chemical Engineering, University of Michigan, 2300 Hayward Street, Ann Arbor, MI 48109, USA.
authors.forename: Meghan J
authors.initials: MJ
authors.lastname: Cuddihy
authors.forename: Yichun
authors.initials: Y
authors.lastname: Wang
authors.forename: Charles
authors.initials: C
authors.lastname: Machi
authors.forename: Joong Hwan
authors.initials: JH
authors.lastname: Bahng
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Kotov
mesh_terms: D001854:Bone Marrow Cells / Q000166:cytology*; D002454:Cell Differentiation / Q000502:physiology*; D002460:Cell Line; D006801:Humans; D020100:Hydrogels / Q000737:chemistry*; D055153:Stem Cell Niche; D023822:Tissue Engineering; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: D020100:Hydrogels