title: Memoirs of a reincarnated T cell.
abstract: In two studies published in this issue of Cell Stem Cell,Nishimura et al. (2013) and Vizcardo et al. (2013) reprogram mature, antigen-specific cytotoxic T cells into induced pluripotent stem cells (iPSCs). The antigen-specific iPSCs can be redifferentiated into "rejuvenated" proliferative T cells and have broad applications for adoptive immunotherapy.
authors.affiliation: National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: Joseph G
authors.initials: JG
authors.lastname: Crompton
authors.forename: Mahendra
authors.initials: M
authors.lastname: Rao
authors.forename: Nicholas P
authors.initials: NP
authors.lastname: Restifo
mesh_terms: D018929:Cell Culture Techniques / Q000379:methods*; D002454:Cell Differentiation / Q000502:physiology*; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology* / Q000378:metabolism*; D058965:MART-1 Antigen / Q000378:metabolism*; D013601:T-Lymphocytes / Q000166:cytology*; D013602:T-Lymphocytes, Cytotoxic / Q000166:cytology* / Q000378:metabolism*
chemical_list: D058965:MART-1 Antigen