title: Preliminary results of surgical and quality of life outcomes of Physiomesh in an international, prospective study.
abstract: Physiomesh is a novel, lightweight, large pore, polypropylene mesh designed to have flexibility that matches the compliance of the abdominal wall in an effort to improve patient quality of life (QOL). The International Hernia Mesh Registry was queried for ventral hernia repair (VHR) and inguinal hernia repair (IHR) with Physiomesh. Demographics, operative and postoperative details, and the Carolinas Comfort Scale (CCS) as a measure of QOL were recorded. Physiomesh was used in 100 patients, 29 IHR and 71 VHR. Their average age was 56.8 +/- 13.7, and BMI was 34.0 +/- 21.0 kg/m2. For IHR, preoperative pain (CCS > or = 2) was present in 41%, but decreased at 1, 6, and 12 months postoperatively to 25.9%, 0%, and 1.6%, while movement limitation decreased from 42.9% to 18.5%, 1.6%, and 3.1%. There were no complications or recurrences. The average VHR measured 66.4 cm2; 93% underwent a laparoscopic repair. Pain was present in 59.1% preoperatively but 21% at 12 months. Movement limitations reduced from 43.2% to 15.8% at 12 months. Mesh sensation was reported in only 10.5% at 1 year. There was 1 recurrence. Physiomesh is well tolerated by patients undergoing IHR and VHR. It is associated with a very favorable long-term QOL.
authors.affiliation: Carolinas Medical Center, Charlotte, North Carolina, USA.
authors.forename: Joel F
authors.initials: JF
authors.lastname: Bradley
authors.forename: Kristopher B
authors.initials: KB
authors.lastname: Williams
authors.forename: Blair A
authors.initials: BA
authors.lastname: Wormer
authors.forename: Victor B
authors.initials: VB
authors.lastname: Tsirline
authors.forename: Amanda L
authors.initials: AL
authors.lastname: Walters
authors.forename: Ronald F
authors.initials: RF
authors.lastname: Sing
authors.forename: Igor
authors.initials: I
authors.lastname: Belyansky
authors.forename: B Todd
authors.initials: BT
authors.lastname: Heniford
mesh_terms: D001315:Australia / Q000453:epidemiology; D015897:Comorbidity; D016208:Databases, Factual; D019544:Equipment Failure Analysis; D005060:Europe / Q000453:epidemiology; D005260:Female; D006552:Hernia, Inguinal / Q000453:epidemiology* / Q000601:surgery*; D059685:Herniorrhaphy / Q000295:instrumentation / Q000706:statistics & numerical data*; D006801:Humans; D038622:Internationality; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction / Q000706:statistics & numerical data; D011183:Postoperative Complications / Q000453:epidemiology*; D015995:Prevalence; D011446:Prospective Studies; D011474:Prosthesis Design; D011788:Quality of Life; D012042:Registries; D012307:Risk Factors; D013526:Surgical Mesh / Q000706:statistics & numerical data*; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology