title: Thrombosis of a developmental venous anomaly in inflammatory bowel disease: case report and radiologic follow-up.
abstract: Developmental venous anomalies (DVAs) are benign embryologic vascular variants, and before the advent of computed tomography and magnetic resonance imaging were supposed to be rare conditions. Usually, DVAs are asymptomatic and accidentally discovered during routine brain imaging studies, but sometimes they can be the cause of disabling neurologic symptoms. We describe the clinical and neuroradiologic follow-up of a 62-year-old man with a history of inflammatory bowel disease (IBD) presenting with new onset epilepsy and intracranial hemorrhage caused by thrombosis of a DVA who fully recovered after treatment with oral anticoagulant therapy. Patients with IBD have an increased risk of thrombosis because of inflammatory activity and the hypercoagulable state. Here we describe the first case of DVA thrombosis in a patient with IBD, and we show clinical and neuroradiologic follow-up after anticoagulant therapy.
authors.affiliation: Institute of Neurology, Università Cattolica, Rome, Italy. Electronic address: fabio.pilato@rm.unicatt.it.
authors.forename: Fabio
authors.initials: F
authors.lastname: Pilato
authors.forename: Rosalinda
authors.initials: R
authors.lastname: Calandrelli
authors.forename: Simona
authors.initials: S
authors.lastname: Gaudino
authors.forename: Paolo
authors.initials: P
authors.lastname: Profice
authors.forename: Matia
authors.initials: M
authors.lastname: Martucci
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Esposito
authors.forename: Cesare
authors.initials: C
authors.lastname: Colosimo
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Di Lazzaro
mesh_terms: D002533:Cerebral Angiography; D002550:Cerebral Veins / Q000002:abnormalities* / Q000000981:diagnostic imaging; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D002538:Intracranial Arteriovenous Malformations / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D020246:Venous Thrombosis / Q000150:complications* / Q000000981:diagnostic imaging
keywords: Epilepsy; developmental venous anomaly; inflammatory bowel disease; intracranial hemorrhage; magnetic resonance imaging; stroke