title: Successful treatment of malakoplakia of the bladder in a kitten.
abstract: A 4-month-old female kitten presented with chronic lower urinary tract signs and Escherichia coli cystitis, and was diagnosed with urinary bladder malakoplakia based upon histopathology. The kitten was treated with a prolonged antibiotic course and the malakoplakia resolved. Malakoplakia is a chronic granulomatous reaction characterized by the formation of Michaelis-Gutman bodies within von Hansemann macrophages. It is well described in humans, but has never been documented in a living veterinary patient. This case report describes the first successful treatment of malakoplakia in veterinary medicine.
authors.affiliation: Southpaws Specialty Surgery for Animals, Moorabbin, Australia. rutland404@gmail.com
authors.forename: Bronwyn E
authors.initials: BE
authors.lastname: Rutland
authors.forename: Judith
authors.initials: J
authors.lastname: Nimmo
authors.forename: Matthew
authors.initials: M
authors.lastname: Goldsworthy
authors.forename: James O
authors.initials: JO
authors.lastname: Simcock
authors.forename: Kenneth W
authors.initials: KW
authors.lastname: Simpson
authors.forename: Charles A
authors.initials: CA
authors.lastname: Kuntz
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D004926:Escherichia coli / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary; D005260:Female; D008287:Malacoplakia / Q000628:therapy / Q000662:veterinary*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use; D001745:Urinary Bladder Diseases / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D014552:Urinary Tract Infections / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary
chemical_list: D000900:Anti-Bacterial Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination