title: Clinical symptoms in fibromyalgia are associated to overweight and lipid profile.
abstract: In order to analyze the association between body mass index (BMI), lipid profile and clinical symptoms in patients with fibromyalgia, we assessed BMI levels, lipid profile and its association with clinical symptoms in 183 patients with fibromyalgia. The patients were evaluated using tender points, FIQ and Visual Analogue Scales of pain (VAS). Serum lipid profile analysis (total cholesterol, triglyceride, HDL, LDL and VLDL), and biochemical parameters were measured in the biochemistry laboratory. The BMI distribution of the nonobese, overweight and obese patients' groups were relatively even with 37.7, 35.5 and 26.8%, respectively, with a mean BMI of 27.3 ± 4.9. The number of tender points showed significantly positive correlation with higher BMI (P < 0.05). A total of 57.9% of patients showed increased levels of total cholesterol, 63.4 % increased levels of LDL cholesterol and 19.9% high levels of triglycerides. BMI, total cholesterol and triglycerides showed high association with some clinical parameters. Overweight and lipid profile could be associated with fibromyalgia symptoms. A treatment program with weight loss strategies, and control in diet and increased physical activity is advised to patients.
authors.affiliation: Dpto. Citología e Histología Normal y Patológica, Facultad de Medicina, Universidad de Sevilla, Avda. Sánchez-Pizjuán s/n, 41009, Sevilla, Spain, mdcormor@us.es.
authors.forename: Mario D
authors.initials: MD
authors.lastname: Cordero
authors.forename: Elísabet
authors.initials: E
authors.lastname: Alcocer-Gómez
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Cano-García
authors.forename: Benito
authors.initials: B
authors.lastname: Sánchez-Domínguez
authors.forename: Patricia
authors.initials: P
authors.lastname: Fernández-Riejo
authors.forename: Ana M
authors.initials: AM
authors.lastname: Moreno Fernández
authors.forename: Ana
authors.initials: A
authors.lastname: Fernández-Rodríguez
authors.forename: Manuel
authors.initials: M
authors.lastname: De Miguel
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004038:Diet, Reducing; D015444:Exercise; D005260:Female; D005356:Fibromyalgia / Q000097:blood* / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D063806:Myalgia / Q000503:physiopathology; D009765:Obesity / Q000097:blood* / Q000503:physiopathology* / Q000628:therapy; D050177:Overweight / Q000097:blood* / Q000503:physiopathology* / Q000628:therapy; D010147:Pain Measurement; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol