title: Post-operative hypertension after total knee arthroplasty and the effects on transfusion rates.
abstract: Transfusions are a cause of significant patient morbidity as well as expense. Anesthesia literature has examined controlled intraoperative hypotension as a means for reducing blood loss and transfusions. Our hypothesis is that inversely increased blood pressure post-operatively would then lead to increased blood loss and transfusions.We examined 105 consecutive patients who underwent TKA. We found a significant odds ratio of 1.123 for pre-operative hematocrit. For post-operative blood pressure, we calculated an insignificant odds ratio of 1.007, proving no relationship between post-operative blood pressure and transfusions.This is the first study to examine increased post-operative blood pressure's contribution to transfusion rates. Although we confirmed that low pre-operative hematocrit contributes to increased transfusions, we did not find a relationship between post-operative blood pressure and transfusions.
authors.affiliation: Department of Orthopedic Surgery, Louisiana State University Health Sciences Center, New Orleans, LA, USA. rrusso@lsuhsc.edu
authors.forename: Russell R
authors.initials: RR
authors.lastname: Russo
authors.forename: Vinod
authors.initials: V
authors.lastname: Dasa
authors.forename: Robert
authors.initials: R
authors.lastname: Duarte
authors.forename: Burton
authors.initials: B
authors.lastname: Beakley
authors.forename: Manish
authors.initials: M
authors.lastname: Mishra
authors.forename: Hilary
authors.initials: H
authors.lastname: Thompson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects*; D016063:Blood Loss, Surgical; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011379:Prognosis; D012189:Retrospective Studies; D065227:Transfusion Reaction