title: The role of radiotherapy and chemotherapy in the treatment of primary adult high grade gliomas: assessment of patients for these treatment approaches and the common immediate side effects.
abstract: Gliomas are the commonest primary brain tumours in adults. They are usually classified and graded according to the criteria by the World Health Organisation. High-grade gliomas are the most malignant primary brain tumours. Conventional therapies include surgery, radiotherapy, and chemotherapy. The tumours often demonstrate high levels of resistance to these conventional therapies, and in spite of treatment advances the prognosis remains poor.
authors.affiliation: Department of Internal Medicine, College of Medical Sciences, University of Calabar, PMB 1278, Nigeria.
authors.forename: E E
authors.initials: EE
authors.lastname: Philip-Ephraim
authors.forename: K I
authors.initials: KI
authors.lastname: Eyong
authors.forename: U E
authors.initials: UE
authors.lastname: Williams
authors.forename: R P
authors.initials: RP
authors.lastname: Ephraim