title: Treatment of cystic craniopharyngioma with 90Y-Colloid. Four clinical cases.
abstract: Craniopharyngioma is a histologically benign and frequently cystic intracranial tumor. It may present aggressive behavior due to compression from nearby structures. Its therapeutic management is complicated because although surgery is the usual treatment of choice, it is not exempt of high morbidity and mortality and frequent tumor recurrence. In craniopharyngiomas with a significant cystic component,internal irradiation with radioactive isotopes is a therapeutic alternative to conventional treatments. We present the cases of four patients with cystic craniopharyngiomas who were treated with intracystic administration of 90Y-colloid, and their evolution after the treatment.
authors.affiliation: Servicio de Medicina Nuclear, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, España. asabatell@bellvitgehospital.cat
authors.forename: A
authors.initials: A
authors.lastname: Sabaté-Llobera
authors.forename: J G
authors.initials: JG
authors.lastname: Rojas-Camacho
authors.forename: J
authors.initials: J
authors.lastname: Mora Salvadó
authors.forename: J J
authors.initials: JJ
authors.lastname: Acebes Martín
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez-Gasén
authors.forename: D
authors.initials: D
authors.lastname: Ramal Leiva
authors.forename: J
authors.initials: J
authors.lastname: Martín-Comín
mesh_terms: D000328:Adult; D003102:Colloids / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003397:Craniopharyngioma / Q000150:complications / Q000532:radiotherapy* / Q000601:surgery; D003399:Craniotomy; D003560:Cysts / Q000532:radiotherapy*; D004172:Diplopia / Q000209:etiology; D005260:Female; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D010291:Paresis / Q000209:etiology; D010911:Pituitary Neoplasms / Q000150:complications / Q000532:radiotherapy* / Q000601:surgery; D019275:Radiopharmaceuticals / Q000008:administration & dosage / Q000627:therapeutic use*; D012074:Remission Induction; D014786:Vision Disorders / Q000209:etiology; D055815:Young Adult; D015021:Yttrium Radioisotopes / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D003102:Colloids; D019275:Radiopharmaceuticals; D015021:Yttrium Radioisotopes
keywords: Craneofaringioma quístico; Cystic craniopharyngioma; Guided radiotherapy; Intracavitary irradiation; Irradiación intracavitaria; Itrio-90 coloide; Radioterapia guiada; Yttrium-90 colloid