title: [A case of huge papillary adenocarcinoma of the gallbladder with marked necrosis].
abstract: A 71-year-old woman was admitted to our hospital for evaluation of a right upper abdominal tumor. A contrast-CT scan demonstrated a huge tumor extending from the hepatic hilum to the pelvic space. The rim of tumor was enhanced. The center of the tumor was not enhanced and thus considered to consist of mucus or necrotic tissues. Preoperative diagnosis as gallbladder carcinoma without infiltrating to peripheral organ was made and subsequent cholecystectomy with full-thickness dissection has been performed. The tumor itself was in a swollen gallbladder, 18 cm in diameter, consisting of necrotic tissues in the lumen. Pathologic diagnosis was papillary adenocarcinoma, classified as pHinf1a, revealing fStage II. In many cases with undifferentiated carcinoma of the gallbladder, the neoplasms grow expansively to become large tumors with marked necrosis. We report a rare case of papillary adenocarcinoma of the gallbladder presenting both a clinical course and radiologic findings indistinguishable from undifferentiated carcinoma of the gallbladder.
authors.affiliation: Department of Gastroenterology, Miyagi Kennan Chukaku Hospital.
authors.forename: Masaru
authors.initials: M
authors.lastname: Onuma
authors.forename: Masahito
authors.initials: M
authors.lastname: Miura
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Fujisaka
authors.forename: Megumi
authors.initials: M
authors.lastname: Zuguchi
authors.forename: Shou
authors.initials: S
authors.lastname: Asonuma
authors.forename: Takeshi
authors.initials: T
authors.lastname: Umemura
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Iioka
authors.forename: Takashi
authors.initials: T
authors.lastname: Outou
authors.forename: Michinaga
authors.initials: M
authors.lastname: Takahashi
authors.forename: Hiroo
authors.initials: H
authors.lastname: Naito
mesh_terms: D000231:Adenocarcinoma, Papillary / Q000473:pathology*; D000368:Aged; D005260:Female; D005706:Gallbladder Neoplasms / Q000473:pathology*; D006801:Humans; D009336:Necrosis