title: OsLYP4 and OsLYP6 play critical roles in rice defense signal transduction.
abstract: Plant innate immunity relies on successful detection of trespassing pathogens through recognizing their microbe-associated molecular patterns (MAMPs) by pattern recognition receptors (PRRs) at the cell surface. We recently reported two rice lysin motif (LysM)-containing proteins, OsLYP4 and OsLYP6, as dual functional PRRs sensing bacterial peptidoglycan (PGN) and fungal chitin. Here we further demonstrated the important roles of OsLYP4 and OsLYP6 in rice defense signaling, as silencing of either LYP impaired the defense marker gene activation induced by either bacterial pathogen Xanthomonas oryzaecola or fungal pathogen Magnaporthe oryzae. Moreover, we found that OsLYP4 and OsLYP6 could form homo- and hetero-dimers, and could interact with CEBiP, suggesting an unexpected complexity of chitin perception in rice.
authors.affiliation: State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources; School of Life Sciences; Sun Yat-sen University; P.R. China.
authors.forename: Bing
authors.initials: B
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources; School of Life Sciences; Sun Yat-sen University; P.R. China.
authors.forename: Jian-Feng
authors.initials: JF
authors.lastname: Li
authors.affiliation: State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources; School of Life Sciences; Sun Yat-sen University; P.R. China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Ao
authors.affiliation: State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources; School of Life Sciences; Sun Yat-sen University; P.R. China.
authors.forename: Zhangqun
authors.initials: Z
authors.lastname: Li
authors.affiliation: State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources; School of Life Sciences; Sun Yat-sen University; P.R. China.
authors.forename: Jun
authors.initials: J
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources; School of Life Sciences; Sun Yat-sen University; P.R. China.
authors.forename: Dongru
authors.initials: D
authors.lastname: Feng
authors.affiliation: State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources; School of Life Sciences; Sun Yat-sen University; P.R. China.
authors.forename: Kangbiao
authors.initials: K
authors.lastname: Qi
authors.affiliation: State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources; School of Life Sciences; Sun Yat-sen University; P.R. China.
authors.forename: Yanming
authors.initials: Y
authors.lastname: He
authors.affiliation: The Plant Protection Research Institute; Guangdong Academy of Agricultural Sciences; P.R. China.
authors.forename: Liexian
authors.initials: L
authors.lastname: Zeng
authors.affiliation: State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources; School of Life Sciences; Sun Yat-sen University; P.R. China.
authors.forename: Jinfa
authors.initials: J
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources; School of Life Sciences; Sun Yat-sen University; P.R. China.
authors.forename: Hong-Bin
authors.initials: HB
authors.lastname: Wang
mesh_terms: D020082:Magnaporthe / Q000276:immunology / Q000472:pathogenicity; D012275:Oryza / Q000276:immunology* / Q000378:metabolism* / Q000382:microbiology; D010935:Plant Diseases / Q000276:immunology / Q000382:microbiology; D057865:Plant Immunity / Q000235:genetics / Q000502:physiology*; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D014974:Xanthomonas / Q000276:immunology / Q000472:pathogenicity
chemical_list: D010940:Plant Proteins
keywords: defense-related gene; innate immunity; lysin motif-containing proteins; pattern recognition receptors; rice