title: [Impact of polycystic ovary syndrome on oocyte and embryo quality].
abstract: This review analyzes the literature concerning oocyte and embryo quality, in case of in vitro fertilization (IVF) for women with polycystic ovary syndrome (PCOS). Alterations in oocyte quality, and consequently in embryo quality, may be due to endocrine and intra-ovarian paracrine changes. However, most of publications find similar biological and clinical results after IVF, with or without microinjection, for women with PCOS compared to those obtained in control populations. Subgroups of more pejorative outcome probably exist within PCOS population. Finally, obesity, which is frequent in PCOS, is clearly deleterious, and multidisciplinary care, including lifestyle modifications, is then needed.
authors.affiliation: Service d'histologie-embryologie-cytogénétique-CECOS, hôpital Jean-Verdier, AP-HP, avenue du 14-Juillet, Bondy, France. nathalie.sermondade@jvr.aphp.fr
authors.forename: N
authors.initials: N
authors.lastname: Sermondade
authors.forename: C
authors.initials: C
authors.lastname: Dupont
authors.forename: P
authors.initials: P
authors.lastname: Massart
authors.forename: I
authors.initials: I
authors.lastname: Cédrin-Durnerin
authors.forename: R
authors.initials: R
authors.lastname: Lévy
authors.forename: C
authors.initials: C
authors.lastname: Sifer
mesh_terms: D004624:Embryo Transfer; D004622:Embryo, Mammalian / Q000502:physiology*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy; D009765:Obesity / Q000150:complications; D009865:Oocytes / Q000502:physiology*; D011085:Polycystic Ovary Syndrome / Q000150:complications / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology; D020554:Sperm Injections, Intracytoplasmic