title: Feed-through insecticides for the control of the sand fly Phlebotomus argentipes.
abstract: Three rodent feed-through studies were conducted to evaluate the efficacy of insecticides to control Phlebotomus argentipes (Diptera: Psychodidae). The initial test evaluated diflubenzuron, eprinomectin, fipronil and ivermectin as feed-through treatments in Rattus rattus (Rodentia: Muridae). In the preliminary trial, all four insecticides yielded 100% mortality of P. argentipes larvae within 20 days of exposure to treated rodent faeces. Based upon the initial results, fipronil was evaluated further as a feed-through utilizing Bandicota bengalensis (Rodentia: Muridae). The B. bengalensis trial evaluated fipronil against both adult and larval sandflies at 250 p.p.m., 100 p.p.m. and 50 p.p.m. The results showed the fipronil treatment to have 100% efficacy against larvae up to 20 days post-treatment and over 74% efficacy against adult sandflies presented with B. bengalensis faeces up to 10 days post-treatment at all three dosage levels. The results of the three studies suggest that all four insecticides may be useful tools with which to control Leishmania vector populations.
authors.affiliation: Genesis Laboratories, Inc., Wellington, CO 80549, USA.
authors.forename: K
authors.initials: K
authors.lastname: Ingenloff
authors.forename: R
authors.initials: R
authors.lastname: Garlapati
authors.forename: D
authors.initials: D
authors.lastname: Poché
authors.forename: M I
authors.initials: MI
authors.lastname: Singh
authors.forename: J L
authors.initials: JL
authors.lastname: Remmers
authors.forename: R M
authors.initials: RM
authors.lastname: Poché
mesh_terms: D000284:Administration, Oral; D000821:Animal Feed / Q000032:analysis*; D000818:Animals; D004132:Diflubenzuron / Q000097:blood / Q000494:pharmacology*; D005243:Feces / Q000737:chemistry; D005247:Feeding Behavior / Q000187:drug effects; D005260:Female; D007300:Insect Control / Q000379:methods*; D007306:Insecticides / Q000097:blood / Q000494:pharmacology*; D007559:Ivermectin / Q000031:analogs & derivatives / Q000097:blood / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects; D008297:Male; D051189:Murinae / Q000378:metabolism; D010691:Phlebotomus / Q000187:drug effects* / Q000254:growth & development; D011720:Pyrazoles / Q000097:blood / Q000494:pharmacology*; D051381:Rats / Q000378:metabolism; D013997:Time Factors
chemical_list: D007306:Insecticides; D011720:Pyrazoles; D007559:Ivermectin; D004132:Diflubenzuron; C082360:fipronil