title: Optimization of Seoul-Fluor-based lipid droplet bioprobes and their application in microalgae for bio-fuel study.
abstract: We synthesized a series of Seoul-Fluor-based lipid droplet bioprobes with a linear range of lipophilicity and identified SF44 and SF58 as SF-based LD bioprobes in microalgae for biofuel research as well as in mammalian cells. Unlike Nile Red, SF-based bioprobes can stain algal LDs with excellent efficiency under the non-invasive and non-cytotoxic conditions.
authors.affiliation: Department of Chemistry, Seoul National University, Seoul, Korea.
authors.forename: Youngjun
authors.initials: Y
authors.lastname: Lee
authors.forename: Sangcheol
authors.initials: S
authors.lastname: Na
authors.forename: Sanghee
authors.initials: S
authors.lastname: Lee
authors.forename: Noo Li
authors.initials: NL
authors.lastname: Jeon
authors.forename: Seung Bum
authors.initials: SB
authors.lastname: Park
mesh_terms: D000818:Animals; D056804:Biofuels; D018533:Biomass; D000460:Chlorophyta / Q000737:chemistry / Q000254:growth & development / Q000378:metabolism; D003594:Cytoplasmic Granules / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry; D006801:Humans; D008055:Lipids / Q000032:analysis / Q000737:chemistry*; D058086:Microalgae / Q000737:chemistry* / Q000254:growth & development / Q000378:metabolism; D015394:Molecular Structure; D010078:Oxazines / Q000737:chemistry; D015203:Reproducibility of Results; D013194:Staining and Labeling / Q000379:methods
chemical_list: D056804:Biofuels; D005456:Fluorescent Dyes; D006576:Heterocyclic Compounds, 4 or More Rings; D008055:Lipids; D010078:Oxazines; C572124:SF44 compound; C044808:nile red