title: Visual simulation through an aspheric aberration-correcting intraocular lens in subjects with different corneal profiles using adaptive optics.
abstract: BACKGROUND
  The aim of this study was to analyse the visual quality of the AcrySof IQ SN60WF(®) intraocular lens (IOL) when combined with different corneal profiles.
  
  
  METHODS
  Ten eyes of 10 participants with no prior history of refractive or cataract surgery were evaluated. An adaptive optics visual simulator was used to simulate the wavefront aberration pattern of an aspheric aberration-correcting IOL (AcrySof IQ SN60WF(®)). Normal corneas (group A), low and high myopic corneal ablations (groups B and C, respectively) and low and high hyperopic corneal ablations (groups D and E, respectively) were also simulated. Monocular distance visual acuities at 100, 50 and 10 per cent of contrast were measured.
  
  
  RESULTS
  At 100, 50 and 10 per cent contrast, no differences were found between groups A and B (p > 0.06 for all contrasts). Group A obtained better values than groups C, D and E for all contrasts (p = 0.031, p = 0.038, p = 0.032 at 100, 50 and 10 per cent of contrast, respectively). At the same time, group B obtained better values than groups C, D and E (p = 0.041, p = 0.042, p = 0.036 at 100, 50 and 10 per cent of contrast, respectively). Within the five groups, the worst results were always obtained for group E (p = 0.017, p = 0.021 and p = 0.025 at 100, 50 and 10 per cent of contrast, respectively).
  
  
  CONCLUSIONS
  The results suggest that the aspheric aberration-correcting IOL studied provides comparable results, when it is combined with normal corneas and with corneas with simulated low myopic ablations. When negative amounts of residual spherical aberration after cataract surgery are expected to be achieved, IOLs with more positive spherical aberration should be considered.
authors.affiliation: Optics and Optometry Department, Universidad Europea de Madrid, Madrid, Spain. j.ruizalcocer@hotmail.com
authors.forename: Javier
authors.initials: J
authors.lastname: Ruiz-Alcocer
authors.forename: David
authors.initials: D
authors.lastname: Madrid-Costa
authors.forename: Santiago
authors.initials: S
authors.lastname: García-Lázaro
authors.forename: César
authors.initials: C
authors.lastname: Albarrán-Diego
authors.forename: Teresa
authors.initials: T
authors.lastname: Ferrer-Blasco
mesh_terms: D000328:Adult; D057108:Corneal Wavefront Aberration / Q000601:surgery*; D006801:Humans; D019654:Lens Implantation, Intraocular; D009216:Myopia / Q000601:surgery; D014792:Visual Acuity
keywords: adaptive optics; intraocular lens; spherical aberration; visual simulation