title: Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel.
authors.affiliation: Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Kamenice 5/A13, 625 00 Brno, Czech Republic.
authors.forename: Tana
authors.initials: T
authors.lastname: Koudelakova
authors.forename: Radka
authors.initials: R
authors.lastname: Chaloupkova
authors.forename: Jan
authors.initials: J
authors.lastname: Brezovsky
authors.forename: Zbynek
authors.initials: Z
authors.lastname: Prokop
authors.forename: Eva
authors.initials: E
authors.lastname: Sebestova
authors.forename: Martin
authors.initials: M
authors.lastname: Hesseler
authors.forename: Morteza
authors.initials: M
authors.lastname: Khabiri
authors.forename: Maryia
authors.initials: M
authors.lastname: Plevaka
authors.forename: Daryna
authors.initials: D
authors.lastname: Kulik
authors.forename: Ivana
authors.initials: I
authors.lastname: Kuta Smatanova
authors.forename: Pavlina
authors.initials: P
authors.lastname: Rezacova
authors.forename: Rudiger
authors.initials: R
authors.lastname: Ettrich
authors.forename: Uwe T
authors.initials: UT
authors.lastname: Bornscheuer
authors.forename: Jiri
authors.initials: J
authors.lastname: Damborsky
mesh_terms: D055162:Biocatalysis; D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D004795:Enzyme Stability; D004798:Enzymes / Q000737:chemistry / Q000378:metabolism*; D019143:Evolution, Molecular; D007700:Kinetics; D056004:Molecular Dynamics Simulation; D015202:Protein Engineering; D012997:Solvents / Q000737:chemistry*
chemical_list: D004798:Enzymes; D012997:Solvents; D004121:Dimethyl Sulfoxide