title: The effect of lacto- and bifidobacteria compositions on the vaginal microflora in cases of intravaginal staphylococcosis.
abstract: The effect of intravaginal injection of Lactobacillus casei IMV B-7280, Lactobacillus acidophilus IMV B-7279, Bifidobacterium animalis VKL and Bifidobacterium animalis VKB strains in various compositions on the range of microflora of the urogenital tract on the model of experimental intravaginal staphylococcosis of mice was determined. It was established that under the influence of various compositions of these strains changes in microflora spectrum occurred the number of representatives of normoflora increased and the number of pathogenic microorganisms, including staphylococci, streptococci, coliform bacteria and fungi, significantly decreased. It was determined that strains of lacto- and bifidobacteria, that were studied, are prospective components of future probiotic drugs efficient in treating staphylococcosis.
authors.affiliation: Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, 154, Acad. Zabolotny St., Kyiv, MSP D03680, Ukraine.
authors.forename: L P
authors.initials: LP
authors.lastname: Babenko
authors.forename: L M
authors.initials: LM
authors.lastname: Lazarenko
authors.forename: L M
authors.initials: LM
authors.lastname: Shynkarenko
authors.forename: V V
authors.initials: VV
authors.lastname: Mokrozub
authors.forename: V S
authors.initials: VS
authors.lastname: Pidgorskyi
authors.forename: M Y
authors.initials: MY
authors.lastname: Spivak
mesh_terms: D000282:Administration, Intravaginal; D000818:Animals; D000898:Antibiosis; D001644:Bifidobacterium / Q000502:physiology*; D015169:Colony Count, Microbial; D004195:Disease Models, Animal; D004755:Enterobacteriaceae / Q000187:drug effects / Q000254:growth & development; D005260:Female; D005658:Fungi / Q000187:drug effects / Q000254:growth & development; D006801:Humans; D007779:Lactobacillus acidophilus / Q000502:physiology*; D007780:Lacticaseibacillus casei / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D019936:Probiotics / Q000008:administration & dosage / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000382:microbiology / Q000628:therapy*; D013210:Staphylococcus / Q000187:drug effects / Q000254:growth & development; D013291:Streptococcus / Q000187:drug effects / Q000254:growth & development; D014621:Vagina / Q000187:drug effects* / Q000382:microbiology