title: Efficacy and safety of rituximab in the treatment of vasculitic leg ulcers associated with hepatitis C virus infection.
abstract: Vasculitic leg ulcers are a cutaneous manifestation of hepatitis C virus (HCV) infection often associated with cryoglobulinemia. Their treatment is difficult and is based on steroids and immunosuppressive drugs with an erratic response and a high probability of adverse reaction. We report three patients with vasculitic leg ulcers associated with hepatitis C virus infection who were treated successfully with rituximab. The pain control and healing were achieved quickly. No adverse effects with rituximab in these patients were presented.
authors.affiliation: Rheumatology Unit, Fundación Valle del Lili, ICESI University, Cali, Colombia.
authors.forename: Fabio
authors.initials: F
authors.lastname: Bonilla-Abadía
authors.forename: Andrés F
authors.initials: AF
authors.lastname: Echeverri
authors.forename: Jorge H
authors.initials: JH
authors.lastname: Izquierdo
authors.forename: Felipe
authors.initials: F
authors.lastname: Cañas
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Cañas