title: Innate lymphoid cells--how did we miss them?
abstract: Innate lymphoid cells (ILCs) are newly identified members of the lymphoid lineage that have emerging roles in mediating immune responses and in regulating tissue homeostasis and inflammation. Here, we review the developmental relationships between the various ILC lineages that have been identified to date and summarize their functions in protective immunity to infection and their pathological roles in allergic and autoimmune diseases.
authors.affiliation: MRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Walker
authors.forename: Jillian L
authors.initials: JL
authors.lastname: Barlow
authors.forename: Andrew N J
authors.initials: AN
authors.lastname: McKenzie
mesh_terms: D000818:Animals; D001249:Asthma / Q000235:genetics / Q000276:immunology; D005075:Biological Evolution; D002450:Cell Communication / Q000276:immunology; D019070:Cell Lineage / Q000235:genetics / Q000276:immunology; D054884:Host-Pathogen Interactions / Q000235:genetics / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000235:genetics / Q000276:immunology; D007113:Immunity, Innate / Q000235:genetics / Q000276:immunology*; D015212:Inflammatory Bowel Diseases / Q000235:genetics / Q000276:immunology; D016131:Lymphocyte Subsets / Q000276:immunology / Q000378:metabolism; D008214:Lymphocytes / Q000276:immunology* / Q000378:metabolism