title: Effects of Brazilian Cardioprotective Diet Program on risk factors in patients with coronary heart disease: a Brazilian Cardioprotective Diet randomized pilot trial.
abstract: OBJECTIVE
  To evaluate the effectiveness of the Brazilian Cardioprotective Diet Program in reducing blood pressures, fasting glucose levels and body mass indices in patients with established atherothrombotic disease.
  
  
  METHODS
  This randomized controlled pilot trial included outpatients who were over 45 years of age with atherothrombotic cardiovascular disease. Group A, who received the Brazilian Cardioprotective Diet Program, had weekly sessions with dietitians. Groups B and C received the usual dietary therapy that is given to patients with cardiovascular diseases as proposed by the Brazilian guidelines. This diet had the same nutrient profile as that given to Group A, but it was customized by the integration of typical Mediterranean foods. The difference between Groups B and C was the number of sessions with the dietitian. Group B received weekly sessions, while group C only had monthly sessions. ClinicalTrials.gov: NCT 01453166.
  
  
  RESULTS
  There was a greater reduction in systolic (7.8%) and diastolic (10.8%) blood pressures in Group A compared with Group B (2.3% and 7.3%), and Group C (3.9% and 4.9%, respectively). Fasting glucose decreased by 5.3% and 2% in Groups A and B, respectively. Fasting glucose increased by 3.7% in Group C. The BMIs decreased by 3.5% and 3.3% in Groups A and B, respectively. Group C did not present with any changes in BMI. However, none of these data showed statistical differences between the groups, which is methodologically acceptable in pilot trials.
  
  
  CONCLUSIONS
  The Brazilian Cardioprotective Diet Program seems to be more effective in reducing blood pressures, fasting glucose levels, weights and BMIs in patients with previous cardiovascular disease compared with the diet that has been proposed by the Brazilian guidelines.
authors.affiliation: Hospital do Coração (IEP-HCor), Research Institute, São Paulo/SP, Brazil. bweber@hcor.com.br
authors.forename: Bernardete
authors.initials: B
authors.lastname: Weber
authors.forename: Andrea Polo
authors.initials: AP
authors.lastname: Galante
authors.forename: Angela Cristine
authors.initials: AC
authors.lastname: Bersch-Ferreira
authors.forename: Camila Ragne
authors.initials: CR
authors.lastname: Torreglosa
authors.forename: Vitor Oliveira
authors.initials: VO
authors.lastname: Carvalho
authors.forename: Elivane da Silva
authors.initials: Eda S
authors.lastname: Victor
authors.forename: Jose Amalth do
authors.initials: JA
authors.lastname: Espírito-Santo
authors.forename: Maria Beatriz
authors.initials: MB
authors.lastname: Ross-Fernandes
authors.forename: Rafael Marques
authors.initials: RM
authors.lastname: Soares
authors.forename: Rosana Perim
authors.initials: RP
authors.lastname: Costa
authors.forename: Enilda de Sousa
authors.initials: Ede S
authors.lastname: Lara
authors.forename: Anna Maria
authors.initials: AM
authors.lastname: Buehler
authors.forename: Otávio
authors.initials: O
authors.lastname: Berwanger
mesh_terms: D000704:Analysis of Variance; D050197:Atherosclerosis / Q000178:diet therapy* / Q000378:metabolism; D001786:Blood Glucose / Q000378:metabolism*; D001794:Blood Pressure / Q000502:physiology*; D015992:Body Mass Index; D001938:Brazil; D002318:Cardiovascular Diseases / Q000517:prevention & control*; D003466:Cultural Characteristics; D004032:Diet / Q000379:methods / Q000592:standards*; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009313:National Health Programs / Q000592:standards*; D010865:Pilot Projects; D012307:Risk Factors
chemical_list: D001786:Blood Glucose