title: Effects of exchange transfusion on cytokine profiles in necrotizing enterocolitis.
abstract: To study the effect of exchange transfusion on cytokine profiles in a patient with necrotizing enterocolitis, the levels of 12 cytokines and serum calprotectin were measured among exchange transfusion. A male extremely low birth weight infant was in non-compensated shock and diagnosed stage 3 necrotizing enterocolitis. Exchange transfusion was performed for critical condition, refractory hypotension and disseminated intravascular coagulation. After exchange transfusion, the patient's blood pressure increased and stabilized. Then an enterostomy was performed and revealed necrosis of the ascending colon. Of the cytokines examined, interleukin-8 and serum calprotectin were high before exchange transfusion and decreased after exchange transfusion.
authors.affiliation: Department of Pediatrics, Toyohashi Municipal Hospital, Aichi, Japan. tokio@med.nagoya-cu.ac.jp
authors.forename: Tokio
authors.initials: T
authors.lastname: Sugiura
authors.forename: Masanori
authors.initials: M
authors.lastname: Kouwaki
authors.forename: Kenji
authors.initials: K
authors.lastname: Goto
authors.forename: Takeshi
authors.initials: T
authors.lastname: Endo
authors.forename: Koichi
authors.initials: K
authors.lastname: Ito
authors.forename: Norihisa
authors.initials: N
authors.lastname: Koyama
authors.forename: Hajime
authors.initials: H
authors.lastname: Togari
mesh_terms: D016207:Cytokines / Q000097:blood*; D020345:Enterocolitis, Necrotizing / Q000097:blood / Q000628:therapy*; D005078:Exchange Transfusion, Whole Blood / Q000379:methods*; D006801:Humans; D062071:Infant, Extremely Premature; D007231:Infant, Newborn; D008297:Male
chemical_list: D016207:Cytokines