title: [A model of intestinal infiltrate in conditions of chronic experiment].
abstract: A chronic intestinal infiltrate model, aiming at a typical inflammatory process simulation, was elaborated in experiment. As a result of experiment on 30 rabbits the quantity of colonies of various causative agents was established, which did not cause the abscess and peritonitis formation. While doing the operation in 60 rabbits chronic infiltrate was formed between abducting and adducting small intestine loops, its mesentery and big omentum; between abducting and adducting large intestine loops, its mesentery and big omentum. The infiltrate formation process was studied up on the 3, 7, 14th and 28th day. Dynamics of changes in microorganisms species and quantity were studied, using microbiological investigations data. The stages of chronic intestinal infiltrate formation were followed up, using histological investigations. Application of the method proposed have permitted to form a chronic infiltrate owing predicted course to reduce the experiment duration and the investigated animals quantity.
authors.forename: I A
authors.initials: IA
authors.lastname: Sukhin
mesh_terms: D000818:Animals; D002908:Chronic Disease; D004195:Disease Models, Animal; D013293:Enterococcus faecalis / Q000254:growth & development; D004926:Escherichia coli / Q000254:growth & development; D005260:Female; D006651:Histocytochemistry; D007420:Intestine, Large / Q000382:microbiology / Q000473:pathology*; D007421:Intestine, Small / Q000382:microbiology / Q000473:pathology*; D008297:Male; D008643:Mesentery / Q000382:microbiology / Q000473:pathology*; D009852:Omentum / Q000382:microbiology / Q000473:pathology*; D010538:Peritonitis / Q000382:microbiology / Q000473:pathology; D011513:Proteus mirabilis / Q000254:growth & development; D011817:Rabbits; D013211:Staphylococcus aureus / Q000254:growth & development