title: Physico-chemical standardization of Sitopaladi churna.
abstract: BACKGROUND
  Standardization of a compound Ayurvedic formulation is a critical and essential issue to be considered in assuring the therapeutic efficacy and safety and to rationalize their use in the health care. Sitopaladi churna is a reputed polyherbal formulation of Ayurveda. It is prescribed for the treatment of pleurodynia, intercostal neuralgia, cold, cough associated with bronchitis, pneumonia, tuberculosis, viral respiratory infection, and in pharyngeal and chest congestion.
  
  
  OBJECTIVE
  The present study aimed at physico-chemical standardization of in-house and two marketed brands of Sitopaladi churna.
  
  
  METHODS
  In our investigation, in-house churna and two commercial brands of Sitopaladi churna were standardized based on powder microscopy, physico-chemical evaluations, thin layer chromatography (TLC) and high performance thin layer chromatography (HPTLC) finger printing as per standard procedures.
  
  
  RESULTS
  The set parameters were sufficient to evaluate the churna based on various physico-chemical parameters.
  
  
  CONCLUSIONS
  The data evolved can be adopted for laying down the standards for the manufacturing units of Sitopaladi churna.
authors.affiliation: Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, Karnataka, India.
authors.forename: Inder Kumar
authors.initials: IK
authors.lastname: Makhija
authors.forename: Chandrashekara Shastry
authors.initials: CS
authors.lastname: Shreedhara
authors.forename: Holavana Hally Nanjundaiah Setty Aswatha
authors.initials: HH
authors.lastname: Ram
keywords: High performance thin layer chromatography; Sitopaladi churna; physico-chemical; standardization