title: Anetoderma secondary to antiphospholipid antibodies.
abstract: Anetoderma is an elastolytic disorder that is associated with a number of infectious and autoimmune disorders. We present a case of a patient with generalized anetoderma, who was later found to have positive antinuclear antibodies and antiphospholipid antibodies (APAs). Numerous other cases have been reported in literature and some authors have suggested that anetoderma is a highly specific sign of APAs, with or without other manifestations of systemic lupus erythematosus or antiphospholipid syndrome [14]. Thus, work up for connective-tissue disorders should be considered in any patients who present with this skin finding.
authors.affiliation: The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, USA.
authors.forename: John
authors.initials: J
authors.lastname: Eungdamrong
authors.forename: Max
authors.initials: M
authors.lastname: Fischer
authors.forename: Rishi
authors.initials: R
authors.lastname: Patel
authors.forename: Shane
authors.initials: S
authors.lastname: Meehan
authors.forename: Miguel
authors.initials: M
authors.lastname: Sanchez
mesh_terms: D057088:Anetoderma / Q000175:diagnosis* / Q000276:immunology*; D017152:Antibodies, Antiphospholipid / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010314:Partial Thromboplastin Time; D011537:Pruritus / Q000209:etiology; D053482:beta 2-Glycoprotein I / Q000276:immunology
chemical_list: D017152:Antibodies, Antiphospholipid; D053482:beta 2-Glycoprotein I