title: Histological and immunohistochemical study of cutaneous angiogenesis process in experimental third-degree skin burns treated with allograft.
abstract: Skin burns are a rather high incidence lesions which, depending on their depth and extension, can severely affect not only the skin but the entire organism. Third-degree skin burns extended on over 20% of the body surface often require skin graft. Skin allograft is a therapeutic alternative when autograft cannot be used. We investigated the allograft influence on the angiogenesis process in third-degree skin burns, using an experimental model. We noticed that the allograft induces a stronger inflammatory reaction associated with intense angiogenesis process by about 10-15% compared to control group.
authors.affiliation: Department of Histology, University of Medicine and Pharmacy of Craiova, Craiova, Romania.
authors.forename: Cristina Jana
authors.initials: CJ
authors.lastname: Busuioc
authors.forename: Florina Carmen
authors.initials: FC
authors.lastname: Popescu
authors.forename: G D
authors.initials: GD
authors.lastname: Mogoşanu
authors.forename: H
authors.initials: H
authors.lastname: Pârvănescu
authors.forename: Liliana
authors.initials: L
authors.lastname: Streba
authors.forename: L
authors.initials: L
authors.lastname: Mogoantă
mesh_terms: D000818:Animals; D002056:Burns / Q000473:pathology / Q000601:surgery*; D007150:Immunohistochemistry; D009389:Neovascularization, Pathologic / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D012867:Skin / Q000098:blood supply* / Q000473:pathology; D016038:Skin Transplantation / Q000379:methods*; D014184:Transplantation, Homologous