title: [Lymphogranuloma venereum].
abstract: Lymphogranuloma venereum is a sexually transmitted disease caused by serovars L1-3 of Chlamydia trachomatis. This infection was originally endemic in tropics and transmitted predominantly by heterosexual contact but since the beginning of the century it spreads in industrialized countries mainly among men having sex with men causing them severe proctitis. In the Czech Republic the first case was diagnosed in 2011. Lymphogranuloma venereum can resemble other forms of anorectal disorders inclusive inflammatory bowel diseases and thus it must be included into differential diagnostic considerations. Definitive diagnosis is based on detection of specific serovars of Chlamydia trachomatis by polymerase chain reaction. In patients with lymphogranuloma venereum it is also necessary to exclude other sexually transmitted diseases, particularly syphilis, HIV and also hepatitis C. The therapy of choice is doxycycline administered for three weeks.
authors.affiliation: Dermatovenerologická Klinika 2. LF UK a Centrum pro Pohlavní Nemocnine Na Bulavce, Praha.
authors.forename: Daniela
authors.initials: D
authors.lastname: Vaňousová
authors.forename: Hana
authors.initials: H
authors.lastname: Zákoucká
authors.forename: Jaroslav
authors.initials: J
authors.lastname: Marvan
authors.forename: David
authors.initials: D
authors.lastname: Jilich
authors.forename: Naděžda
authors.initials: N
authors.lastname: Vojáčková
authors.forename: Jana
authors.initials: J
authors.lastname: Hercogová
authors.forename: Ladislav
authors.initials: L
authors.lastname: Machala
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D008219:Lymphogranuloma Venereum / Q000175:diagnosis / Q000628:therapy / Q000635:transmission