title: Chiral separations by simulated moving bed method using polysaccharide-based chiral stationary phases.
abstract: Generally, in using chromatography as an industrial-scale production process, batch separation is not adequate from the standpoint of productivity and mobile phase consumption; thus, a continuous separation is preferred. The simulated moving bed (SMB) method is one of the best popular practices of continuous chromatographic separation. In this chapter, I would like to introduce actual practices of chiral SMB using polysaccharide-derived chiral stationary phases (CSPs), together with some laboratory-scale separation data.
authors.affiliation: Daicel Corporation, Niigata, Japan. to_minoda@jp.daicel.com
authors.forename: Toshiharu
authors.initials: T
authors.lastname: Minoda
mesh_terms: D002845:Chromatography / Q000379:methods; D008962:Models, Theoretical; D011134:Polysaccharides / Q000032:analysis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D011134:Polysaccharides