title: Bioceramics for osteogenesis, molecular and cellular advances.
abstract: The remarkable need for bone tissue replacement in clinical situations, its limited availability and some major drawbacks of autologous (from the patient) and allogeneic (from a donor) bone grafts are driving researchers to search for alternative approaches for bone repair. In order to develop an appropriate bone substitute, one should understand bone structure and properties and its growth, which will guide researchers to select the optimal conditions for tissue culture and implantation. It's well accepted that bioceramics are excellent candidates as bone replacement with osteogenesis, osteoinduction and osteoconduction capacity. Therefore, the molecular and cellular interactions that take place at the surface of bioceramics and their relevance in osteogenesis excites many researchers to delve deeper into this line of research.
authors.affiliation: Research and Development Laboratory, Alvimedica Medical Technologies, Catalca, Istanbul, Turkey. handemirkiran@yahoo.com
authors.forename: Hande
authors.initials: H
authors.lastname: Demirkiran
mesh_terms: D001672:Biocompatible Materials / Q000627:therapeutic use; D001847:Bone Diseases / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D018786:Bone Substitutes / Q000627:therapeutic use*; D002516:Ceramics / Q000627:therapeutic use*; D006801:Humans; D010012:Osteogenesis / Q000235:genetics / Q000502:physiology*; D023822:Tissue Engineering / Q000379:methods / Q000639:trends*
chemical_list: D001672:Biocompatible Materials; D018786:Bone Substitutes