title: [Effect of two short striae incision or traditional "L" shaped incision in neck dissection of differentiated thyroid carcinoma on serum trauma cytokines].
abstract: OBJECTIVE
  To compare the trauma of neck dissection on the human body between two-striae incision and traditional "L" shaped incision by serum trauma cytokines.
  
  
  METHODS
  Patients with differentiated thyroid carcinoma hospitized from December 2008 to July 2011 were divided into 2 groups according to their own will. The first group 26 patients) had two-striae incision and the second group 32 patients) had traditional "L" shaped incision. The serum level of interleukin(IL)-2, IL-6 and C-reactive protein (CRP) in all patients were examined 1 day before and 1, 3 and 5 days after the surgery.
  
  
  RESULTS
  No statistical significance was found between the 2 groups, although level of IL-2 decreased 1 day after the surgery, but recovered to normal 3 days later. The level of IL-6 in both groups increased 1 day after the surgery, began to decrease 3 days after the surgery, and recovered to normal 5 days after the surgery. The level of CRP suggested statistical significance (P<0.05), which increased obviously 1, 3 and 5 days after the surgery. No statistical difference was found before or after the surgery between the 2 groups (P>0.05). After follow-up for 8-40 months, no local recurrence or lymph node metastasis was found.
  
  
  CONCLUSIONS
  Compared with the traditional "L" shaped incision, two-striae incision in neck dissection does not increase the serum level of trauma cytokines and trauma to human body after the surgery. Two-striae incision is an ideal surgical approach to differentiated thyroid carcinoma.
authors.affiliation: Department of Mammary Gland, Tumor Hospital of Xinjiang Medical University, Urumqi, China.
authors.forename: Zhongli
authors.initials: Z
authors.lastname: Geng
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Meihui
authors.initials: M
authors.lastname: Shan
authors.forename: Guanghui
authors.initials: G
authors.lastname: Ren
authors.forename: Chao
authors.initials: C
authors.lastname: Dong
authors.forename: Binlin
authors.initials: B
authors.lastname: Ma
mesh_terms: D000328:Adult; D002097:C-Reactive Protein / Q000378:metabolism; D002291:Carcinoma, Papillary / Q000097:blood / Q000601:surgery; D016207:Cytokines / Q000097:blood*; D005260:Female; D006801:Humans; D007376:Interleukin-2 / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection / Q000379:methods*; D013964:Thyroid Neoplasms / Q000097:blood / Q000601:surgery*
chemical_list: D016207:Cytokines; D007376:Interleukin-2; D015850:Interleukin-6; D002097:C-Reactive Protein