title: Management of a pregnancy complicated by pompe disease.
abstract: Background. As more women with metabolic muscle diseases reach reproductive age, knowledge of these diseases and their impact on pregnancy is necessary. Case. 23-year-old G1P0 with juvenile-onset Pompe disease (PD) delivered a viable infant by cesarean section at 32 weeks and 6 days. The pregnancy was complicated by worsening maternal pulmonary status, muscular strength, and mobility. Conclusion. The management of pregnancies complicated by Pompe disease requires a multidisciplinary approach, including expertise in neuromuscular disease, maternal-fetal medicine, biochemical genetics, pulmonology, anesthesia, and dietetics.
authors.affiliation: Division of Clinical and Biochemical Genetics, Department of Medical and Molecular Genetics, Indiana University School of Medicine, 975 West Walnut Street, IB 130, Indianapolis, IN 46202, USA.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Weida
authors.forename: B E
authors.initials: BE
authors.lastname: Hainline
authors.forename: C
authors.initials: C
authors.lastname: Bodkin
authors.forename: M K
authors.initials: MK
authors.lastname: Williams