title: Burkholderia contaminans: unusual cause of biliary sepsis.
abstract: We report a case of biliary tract infection caused by a strain of Burkholderia contaminans, a member of the Burkholderia cepacia complex. The patient developed sepsis after endoscopic retrograde cholangiopancreatography (ERCP). Gram-negative bacilli were isolated from blood and bile cultures. Automated bacterial identification systems identified the organism as Burkholderia cepacia, whereas DNA sequence analysis revealed that the recA gene isolate was identical to that of B. contaminans. The patient responded to therapy with the antibiotics trimethoprim/sulfamethoxazole and biliary tract decompression. This case suggests that B. contaminans can be a causative agent of healthcare-associated biliary tract infections such as ERCP-related cholangitis.
authors.affiliation: Division of Infectious Disease Therapeutics, Department of Microbiology and Infectious Diseases, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan, ohji@sanynet.ne.jp.
authors.forename: Goh
authors.initials: G
authors.lastname: Ohji
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Ohkusu
authors.forename: Akihiro
authors.initials: A
authors.lastname: Toguchi
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Otsuka
authors.forename: Naoto
authors.initials: N
authors.lastname: Hosokawa
authors.forename: Kentaro
authors.initials: K
authors.lastname: Iwata
mesh_terms: D001660:Biliary Tract Diseases / Q000382:microbiology; D001661:Biliary Tract Neoplasms / Q000175:diagnosis / Q000382:microbiology; D019117:Burkholderia / Q000302:isolation & purification*; D019121:Burkholderia Infections / Q000382:microbiology; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D018805:Sepsis / Q000382:microbiology*