title: Chiral recognition in separation science: an overview.
abstract: Chiral recognition phenomena play an important role in nature as well as analytical separation sciences. In separation sciences such as chromatography and capillary electrophoresis, enantiospecific interactions between the enantiomers of an analyte and the chiral selector are required in order to observe enantioseparations. Due to the large structural variety of chiral selectors applied, different mechanisms and structural features contribute to the chiral recognition process. This chapter briefly illustrates the current models of the enantiospecific recognition on the structural basics of various chiral selectors.
authors.affiliation: Department of Pharmaceutical/Medicinal Chemistry, Friedrich Schiller University Jena, Jena, Germany. gerhard.scriba@uni-jena.de
authors.forename: Gerhard K E
authors.initials: GK
authors.lastname: Scriba
mesh_terms: D052157:Aptamers, Nucleotide / Q000032:analysis / Q000737:chemistry; D047250:Calixarenes / Q000032:analysis / Q000737:chemistry; D002845:Chromatography / Q000379:methods*; D043844:Crown Ethers / Q000032:analysis / Q000737:chemistry; D003505:Cyclodextrins / Q000032:analysis / Q000737:chemistry; D019075:Electrophoresis, Capillary / Q000379:methods*; D007474:Ion Exchange; D047028:Macrocyclic Compounds / Q000032:analysis / Q000737:chemistry; D008823:Micelles; D008962:Models, Theoretical; D011108:Polymers / Q000032:analysis / Q000138:chemical synthesis; D011134:Polysaccharides / Q000032:analysis / Q000737:chemistry; D011487:Protein Conformation; D011506:Proteins / Q000032:analysis / Q000737:chemistry; D012709:Serum Albumin / Q000032:analysis / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D052157:Aptamers, Nucleotide; D043844:Crown Ethers; D003505:Cyclodextrins; D047028:Macrocyclic Compounds; D008823:Micelles; D011108:Polymers; D011134:Polysaccharides; D011506:Proteins; D012709:Serum Albumin; D047250:Calixarenes