title: Palladium-catalyzed intermolecular desulfinylative cross-coupling of heteroaromatic sulfinates.
abstract: Beauty lies in simplicity: An efficient and environmentally benign palladium-catalyzed protocol has been developed using a sulfinate as a nucleophilic coupling partner. The sulfinate position is arylated chemoselectively in very good yields. The bench-stable, non-hygroscopic heteroaromatic sulfinate salts rapidly undergo cross-coupling without the need of a co-catalyst, base, or additives (see scheme; mw = microwave).
authors.affiliation: Chemistry and Biochemistry, Concordia University, 7141 rue Sherbrooke O. Montréal, QC, H4B 1R6, Canada.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Sévigny
authors.forename: Pat
authors.initials: P
authors.lastname: Forgione
mesh_terms: D002384:Catalysis; D008872:Microwaves; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D012492:Salts / Q000737:chemistry*; D013452:Sulfonium Compounds / Q000737:chemistry*
chemical_list: D012492:Salts; D013452:Sulfonium Compounds; D010165:Palladium