title: Randomized, controlled clinical trial evaluating the efficacy of pulsed signal therapy in dogs with osteoarthritis.
abstract: OBJECTIVE
  To evaluate the efficacy of pulsed signal therapy (PST) in reducing pain and increasing function in dogs with osteoarthritis (OA) using a randomized, blinded, controlled clinical trial.
  
  
  METHODS
  Randomized, controlled, blinded clinical trial.
  
  
  METHODS
  Adult dogs (n = 60) with moderate-to-severe clinical signs of OA.
  
  
  METHODS
  Dogs were randomized by age into 2 groups: dogs ≥ 9 years and dogs < 9-years old. The control group received 1 hour of rest in hospital for 9 consecutive days and dogs in the treatment group received PST for 1 hour on 9 consecutive days. Goniometry and gait analysis were performed, and the Canine Brief Pain Inventory (CBPI) questionnaire was given to the owners to fill out without supervision. Outcome measures were repeated at the end of treatment (Day 11) and 6 weeks after beginning treatment (Day 42).
  
  
  RESULTS
  The PST group performed significantly better than the control group as measured by the CBPI Severity and Interference scores (P < .01). Extension (P = .04) and peak vertical force (PVF) (P = .03) were not statistically significant after adjusting for multiple comparisons.
  
  
  CONCLUSIONS
  The group receiving PST performed better than the treatment group according to owner assessment.
authors.affiliation: Veterinary Teaching Hospital, University of Illinois College of Veterinary Medicine, Champaign Urbana, IL, USA. msullivan.dvm@gmail.com
authors.forename: Meghan O
authors.initials: MO
authors.lastname: Sullivan
authors.forename: Wanda J
authors.initials: WJ
authors.lastname: Gordon-Evans
authors.forename: Kim E
authors.initials: KE
authors.lastname: Knap
authors.forename: Richard B
authors.initials: RB
authors.lastname: Evans
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000628:therapy*; D004285:Dogs; D060733:Electromagnetic Radiation; D010003:Osteoarthritis / Q000628:therapy / Q000662:veterinary*; D016896:Treatment Outcome