title: Prolonged fever and splinter hemorrhages in an immunocompetent traveler with disseminated histoplasmosis.
abstract: We present a case of progressive disseminated histoplasmosis in an immunocompetent traveler. Histoplasmosis was acquired in South America; its manifestations included prolonged fever, splinter hemorrhages, erythema multiforme, arthritis, and mediastinal lymphadenopathy. To the best of our knowledge no splinter hemorrhages had previously been reported in a patient with histoplasmosis.
authors.affiliation: Internal Medicine B, Rambam Medical Center, Haifa, Israel.
authors.forename: Roni
authors.initials: R
authors.lastname: Bitterman
authors.forename: Ilana
authors.initials: I
authors.lastname: Oren
authors.forename: Yuval
authors.initials: Y
authors.lastname: Geffen
authors.forename: Hannah
authors.initials: H
authors.lastname: Sprecher
authors.forename: Eli
authors.initials: E
authors.lastname: Schwartz
authors.forename: Ami
authors.initials: A
authors.lastname: Neuberger
mesh_terms: D000284:Administration, Oral; D000935:Antifungal Agents / Q000008:administration & dosage; D001168:Arthritis / Q000209:etiology; D001706:Biopsy; D004271:DNA, Fungal; D005334:Fever / Q000209:etiology; D005800:Genes, Fungal; D006470:Hemorrhage / Q000209:etiology; D006658:Histoplasma / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity; D006660:Histoplasmosis / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage*; D008206:Lymphatic Diseases / Q000473:pathology; D008297:Male; D008875:Middle Aged; D055613:Multiple Pulmonary Nodules / Q000209:etiology; D017422:Sequence Analysis, DNA / Q000379:methods*; D012698:Serologic Tests / Q000379:methods; D014195:Travel; D016896:Treatment Outcome; D015431:Weight Loss
chemical_list: D000935:Antifungal Agents; D004271:DNA, Fungal; D017964:Itraconazole