title: Vitamin-induced intracellular electrons are the mechanism for their well-known beneficial effects: a review.
abstract: A new conception of the action mechanisms of vitamins and some other compounds without a vitamin status is briefly presented. It is based on results obtained through pulse radiolysis, molecular radiation biological investigations, and in vitro studies. The data clearly show that antioxidant vitamins (C, E, β-carotene) and B vitamins and related compounds possess the capability to emit "solvated electrons" in aqueous solutions or polar media. In consequence, the well-known vitamin effects are attributed to the action of the emitted solvated electrons and the resulting vitamin free radicals rather than the vitamin molecules per se, as generally accepted.
authors.affiliation: Section of Radiation Biology, Department of Nutritional Sciences, Faculty of Life Sciences, University of Vienna, Vienna, Austria. nikola.getoff@univie.ac.at
authors.forename: Nikola
authors.initials: N
authors.lastname: Getoff
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000378:metabolism; D002462:Cell Membrane / Q000737:chemistry / Q000378:metabolism*; D004583:Electrons; D005609:Free Radicals / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D014815:Vitamins / Q000737:chemistry / Q000378:metabolism*
chemical_list: D000975:Antioxidants; D005609:Free Radicals; D014815:Vitamins