title: Enantioseparations by thin-layer chromatography.
abstract: An up-to-date overview of thin-layer chromatography (TLC) techniques for chiral separations of various significant and/or recent examples of enantioresolutions is reported. Furthermore, examples for chiral separations obtained on achiral commercially available C18 TLC plates are described in detail. These include the enantioseparation of methylthiohydantoin-phenylalanine and methylthiohydantoin-tyrosine using hydroxyethyl-β-cyclodextrin as mobile phase additive and the separation of the enantiomers of warfarin and p-chlorowarfarin using bovine serum albumin as mobile phase additive.
authors.affiliation: Department of Chemistry, University of Florence, Sesto Fiorentino, Italy. massimo.delbubba@unifi.it
authors.forename: Massimo
authors.initials: M
authors.lastname: Del Bubba
authors.forename: Leonardo
authors.initials: L
authors.lastname: Checchini
authors.forename: Alessandra
authors.initials: A
authors.lastname: Cincinelli
authors.forename: Luciano
authors.initials: L
authors.lastname: Lepri
mesh_terms: D000818:Animals; D002417:Cattle; D002482:Cellulose / Q000032:analysis / Q000737:chemistry; D002855:Chromatography, Thin Layer / Q000379:methods*; D054802:Molecular Imprinting / Q000379:methods; D010649:Phenylalanine / Q000032:analysis / Q000737:chemistry; D011108:Polymers / Q000032:analysis / Q000737:chemistry; D012710:Serum Albumin, Bovine / Q000032:analysis / Q000378:metabolism; D013867:Thiohydantoins / Q000032:analysis / Q000737:chemistry; D014443:Tyrosine / Q000032:analysis / Q000737:chemistry; D014859:Warfarin / Q000032:analysis / Q000737:chemistry; D047392:beta-Cyclodextrins / Q000032:analysis / Q000378:metabolism
chemical_list: D011108:Polymers; D013867:Thiohydantoins; D047392:beta-Cyclodextrins; D012710:Serum Albumin, Bovine; D014443:Tyrosine; D010649:Phenylalanine; D014859:Warfarin; C023447:methylthiohydantoin; D002482:Cellulose