title: Recurrence of Crohn's disease in end ileostomies.
abstract: : It appears well established that the recurrence rates following operations for Crohn's disease of ileum and colon are higher after anastomotic operations than after an end ileostomy. To obtain further information regarding the rate of recurrence following end ileostomy we reviewed the charts of 182 patients: 117 with involvement of the ileum as well as the colon, and 65 with Crohn's colitis only, who were operated upon at the Mt. Sinai Hospital during 1952-1984. They were followed until death or the first ileostomy revision or the last contact. Of the ileocolitis group, 50 patients (43%), and of the colitis group, nine patients (14%) required an ileostomy revision. Of the 50 with ileocolitis, 34 (29%) and four of the colitis group (6.2%) had revisions done primarily for recurrent Crohn's disease at or near the stoma. The estimated overall cumulative probability of recurrence was 50% twenty years following ileostomy, and was significantly higher in the ileocolitis group than in the colitis group (64% vs. 15%; p < 0.001), with mean follow-up durations of 6.5 and 7.5 years, respectively. The probability of ileostomy revision for any reason was also significantly higher for patients with ileocolitis (74% vs. 34%; p < 0.001). We conclude that the site of initial Crohn's disease plays a role in the recurrence of disease in an end ileostomy, with a better outlook for patients with colonic involvement alone.
authors.affiliation: Department of Medicine, Dr. Henry D. Janowitz Division of Gastroenterology, *Department of Surgery, and †Department of Biomathematical Sciences, Mount Sinai School of Medicine of the City University of New York, New York, New York, U.S.A.
authors.forename: I
authors.initials: I
authors.lastname: Ho
authors.forename: A J
authors.initials: AJ
authors.lastname: Greenstein
authors.forename: C A
authors.initials: CA
authors.lastname: Bodian
authors.forename: H D
authors.initials: HD
authors.lastname: Janowitz