title: [The clinical analysis of corneal interface fluid syndrome].
abstract: OBJECTIVE
  To analysis the clinical characteristics of corneal interface fluid syndrome (IFS).
  
  
  METHODS
  This is a retrospective study. During Jun. 2007 to Oct. 2011. Eight cases (12 eyes) of IFS were diagnosed at Henan Eye Institute. The history and complete ophthalmic examination that include Slit-lamp examination, Slit-lamp photography, IOP, anterior segment OCT (AS-OCT), confocal microscopic exams were recorded.
  
  
  RESULTS
  In total 8 cases (12 eyes), 4 cases were bilateral, 4 cases were unilateral. Six patients were male and 2 were female. The age of the patients ranged from 19 to 35 years. Post-lasik steroid-induced elevated IOP was 4 eyes in 2 patients. Primary open angle glaucoma was 4 eyes in 2 patients. 1 patient (1 eye) was Posner-Shlossman syndrome, 1 patient (1 eye) was pigmented glaucoma, 1 patient (1 eye) was post-lasik traumatic iritis. 1 patient (1 eye) got IFS after repeated flap reposition because of epithelium ingrowth. Slit-lamp exam indicated edematous corneal, lamellar haze, interface fluids accumulation. AS-OCT showed obvious interface dark area. Confocal microscopy exam showed edematous corneal flap, more oval and large keratocytes' nuclei but no inflammatory cells.
  
  
  CONCLUSIONS
  IFS is a rare but serious complication after LASIK. The main causes are high intraocular pressure and/or dysfunction of corneal endothelium. Careful exam by slit-lamp may help diagnosis, and further AS-OCT and/or in vivo confocal microscopy exam will confirm it.
authors.affiliation: Henan Eye Institute, Henan Key Laboratory of Keratonosus, Zhengzhou, China.
authors.forename: Chen-jiu
authors.initials: CJ
authors.lastname: Pang
authors.forename: Li-ya
authors.initials: LY
authors.lastname: Wang
authors.forename: Hai-ying
authors.initials: HY
authors.lastname: Peng
authors.forename: Jin
authors.initials: J
authors.lastname: Li
authors.forename: Shu-yin
authors.initials: SY
authors.lastname: Li
authors.forename: Chao
authors.initials: C
authors.lastname: Niu
authors.forename: Wei-jing
authors.initials: WJ
authors.lastname: Yin
mesh_terms: D000328:Adult; D015715:Corneal Edema / Q000175:diagnosis / Q000209:etiology; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects; D008297:Male; D012189:Retrospective Studies; D055815:Young Adult