title: Prostate cancer with clear cell features and an unusual nested-like pattern of growth: a case report.
abstract: BACKGROUND
  Clear cell carcinoma of the prostate is rare, with the majority of reports consisting of a single case study.
  
  
  METHODS
  We report a case of prostate cancer with unusual cytoplasmic clearing and a nested-like pattern of growth observed in an 80-year-old patient with lower urinary tract obstruction. Emphasis is placed upon differential diagnosis and the distinction from other clear cell carcinomas arising in the urinary tract, both at a histological and immunohistochemical level.
  
  
  CONCLUSIONS
  Androgen receptor immunohistochemistry seems to be a useful tool to distinguish prostate origin from secondary clear cell tumors.
authors.affiliation: Public Assistance Hospital of Paris, Department of Pathology, La Pitié-Salpetriere Hospital, University UPMC Paris VI, Paris, France. justinevarinot@hotmail.com
authors.forename: Justine
authors.initials: J
authors.lastname: Varinot
authors.forename: Sarah
authors.initials: S
authors.lastname: Drouin
authors.forename: Morgan
authors.initials: M
authors.lastname: Rouprêt
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Montironi
authors.forename: Antonio
authors.initials: A
authors.lastname: Lopez-Beltran
authors.forename: Eva
authors.initials: E
authors.lastname: Compérat
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000473:pathology*; D000369:Aged, 80 and over; D003593:Cytoplasm / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology; D008297:Male; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*