title: Infantile acne treated with oral isotretinoin.
abstract: In contrast to adolescent acne, infantile acne (IA) is a rare condition with only a limited body of available literature. In this descriptive, retrospective study, we reviewed six cases from 2002 to 2010 treated with oral isotretinoin. The average age of onset was 6.16 months (range 0-21 mos). Consistent with the previous, limited literature, we found predominantly boys are affected, a predilection for the cheeks, and a polymorphic inflammatory morphology. Two patients had a family history of acne. All cases were successfully and safely treated with oral isotretinoin. The suggested treatment of childhood acne is similar to that of adolescents (graded according to the severity of the skin disease and risk of scarring). Oral isotretinoin appears to be an effective and safe treatment for severe IA.
authors.affiliation: Department of Dermatology, Roskilde Hospital, Health Sciences Faculty, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Iben Marie
authors.initials: IM
authors.lastname: Miller
authors.forename: Begoña
authors.initials: B
authors.lastname: Echeverría
authors.forename: Antonio
authors.initials: A
authors.lastname: Torrelo
authors.forename: Gregor Borut Ernst
authors.initials: GB
authors.lastname: Jemec
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy*; D000284:Administration, Oral; D017668:Age of Onset; D003879:Dermatologic Agents / Q000008:administration & dosage*; D005148:Facial Dermatoses / Q000188:drug therapy; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015474:Isotretinoin / Q000008:administration & dosage*; D008297:Male; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D003879:Dermatologic Agents; D015474:Isotretinoin