title: Food allergy in Lebanon: is sesame seed the "middle eastern" peanut.
abstract: A randomly sampled, cross-sectional serology test-based survey was conducted in Lebanon to describe the pattern of food allergy among Lebanese population. The prevalence of specific Immunoglobulin E (IgE) to food allergens was investigated in 20 laboratories in different regions of Lebanon by an immunoblot assay over a 1 year period. Clinical correlation was determined in two university hospitals. There were 1842 patients with suspected IgE-mediated food allergic reactions tested for specific IgE upon their physician's request. Clinical correlation was done in 93 patients. We identified 386 out of 1842 (20.95%) patients with positive specific IgE to food allergens. The clinical presentations were cutaneous, digestive, and anaphylaxis. The major cause of allergy was cow's milk in infants and young children, hazelnut and wheat flour in adults. Although specific IgE to peanut in infants, children, and adults were higher than for sesame, peanut-induced allergic reactions were mild, in contrary to sesame where anaphylaxis was the only clinical manifestation. Recently, sesame has been recognized as an increasingly frequent and potentially severe allergen. Further studies with double-blind, placebo-controlled food challenge are needed to establish the real prevalence of food allergy in Lebanon, and to determine the most common allergens taking in consideration the nutritional habits of our population.
authors.affiliation: From the 1Hotel Dieu de France hospital, Internal Medicine Department, Allergy and Immunology Section; 2Hotel Dieu de France hospital, Laboratory Department, Division of Hematology and Immunology; 3Hammoud Hospital, Laboratory Department, Division of Hematology and Immunology.
authors.forename: Carla
authors.initials: C
authors.lastname: Irani
authors.forename: George
authors.initials: G
authors.lastname: Maalouly
authors.forename: Mirna
authors.initials: M
authors.lastname: Germanos
authors.forename: Hassan
authors.initials: H
authors.lastname: Kazma