title: Glyconanotechnology.
abstract: Glyconanotechnology can be seen as the synergy between nanotechnology and glycan related biological and medical problems. This review focuses on the crosstalk of glycoscience and nanotechnology, which will lead to a deeper understanding of glycobiology and to new glyco-materials with improved design and synergistic properties derived from glycoscience concepts for future nanodevices. It is intended to provide the glycoscientist with an application-oriented entry to the possibilities of nanotechnologies for his research. The most recent examples of glyco-nanomaterials as multivalent scaffolds for drug delivery, enzyme inhibition and for vaccine development, glycan functionalized quantum dots and nanoparticles in molecular imaging, biosensors for lectin/glycan detection based on nanomaterials, and new concepts for the affinity separation and analysis using nanomaterials or nanotools are revised.
authors.affiliation: Biofunctional Nanomaterials Unit, CIC biomaGUNE, P° de Miramón 182, Parque Tecnológico, 20009 San Sebastian, Spain. nreichardt@cicbiomagune.es
authors.forename: Niels C
authors.initials: NC
authors.lastname: Reichardt
authors.forename: Manuel
authors.initials: M
authors.lastname: Martín-Lomas
authors.forename: Soledad
authors.initials: S
authors.lastname: Penadés
mesh_terms: D015374:Biosensing Techniques; D054794:Glycomics; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors; D006801:Humans; D037102:Lectins / Q000032:analysis; D053758:Nanoparticles / Q000737:chemistry; D036103:Nanotechnology; D037742:Nanotubes, Carbon / Q000737:chemistry; D009369:Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology; D011134:Polysaccharides / Q000032:analysis / Q000737:chemistry*; D045663:Quantum Dots; D018074:Vaccines, Conjugate / Q000737:chemistry / Q000276:immunology
chemical_list: D037102:Lectins; D037742:Nanotubes, Carbon; D011134:Polysaccharides; D018074:Vaccines, Conjugate; D006026:Glycoside Hydrolases