title: [Literature review report on safety evaluation about Kudiezi injection].
abstract: OBJECTIVE
  To explore safety evaluation information about Kudiezi injection used in the clinical practice.
  
  
  METHODS
  Three Chinese literature databases were searched and 96 articles were downloaded. Safety information about the study question was extracted by researchers in the Excel form. Finally, 22 articles including 24 case reports were analyzed in this article. Five aspects about safety information were summarized.
  
  
  RESULTS
  It was found that all the adverse drug reaction reports in the literature were improper. There was no clear causality relation inference. It was inaccurate that those reports were identified as adverse drug reactions.
  
  
  CONCLUSIONS
  Although 24 case reports were identified as adverse drug reaction the evidence for each report was insufficient. There is no scientific causality judgment among these reports, which were implied little significance to future health decision about Kudiezi injection.
authors.affiliation: Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. okfrom2008@hotmail.com
authors.forename: Xing
authors.initials: X
authors.lastname: Liao
authors.forename: Hao
authors.initials: H
authors.lastname: Shen
authors.forename: Yan-Ming
authors.initials: YM
authors.lastname: Xie
authors.forename: Wen
authors.initials: W
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Yang
authors.forename: Zhi-Guo
authors.initials: ZG
authors.lastname: Lv
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002986:Clinical Trials as Topic; D064420:Drug-Related Side Effects and Adverse Reactions; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055815:Young Adult
chemical_list: D004365:Drugs, Chinese Herbal