title: Molecular epidemiological surveillance of multidrug-resistant Pseudomonas aeruginosa isolates in a pediatric population of patients with cystic fibrosis and determination of risk factors for infection with the Houston-1 strain.
abstract: Multiyear molecular epidemiological surveillance of multidrug-resistant Pseudomonas aeruginosa (MRPA) in a pediatric cystic fibrosis care center identified an endemic MRPA strain (Houston-1). Recent hospitalization was found to be a statistically significant risk factor for acquisition of the endemic strain. Multiple infection control improvements led to the reduced incidence of the Houston-1 strain in the CF population.
authors.affiliation: Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA. raluna@bcm.edu
authors.forename: Ruth Ann
authors.initials: RA
authors.lastname: Luna
authors.forename: Laura A
authors.initials: LA
authors.lastname: Millecker
authors.forename: C Renee
authors.initials: CR
authors.lastname: Webb
authors.forename: Sally K
authors.initials: SK
authors.lastname: Mason
authors.forename: Elaine M
authors.initials: EM
authors.lastname: Whaley
authors.forename: Jeffrey R
authors.initials: JR
authors.lastname: Starke
authors.forename: Peter W
authors.initials: PW
authors.lastname: Hiatt
authors.forename: James
authors.initials: J
authors.lastname: Versalovic
mesh_terms: D016000:Cluster Analysis; D003550:Cystic Fibrosis / Q000150:complications*; D024901:Drug Resistance, Multiple, Bacterial; D005838:Genotype; D006776:Hospitals, Pediatric; D006801:Humans; D015994:Incidence; D017053:Infection Control / Q000379:methods; D017720:Molecular Epidemiology; D058889:Molecular Typing; D011552:Pseudomonas Infections / Q000453:epidemiology* / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000145:classification / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D012307:Risk Factors