title: [The influence of subclinical thyroid dysfunction on cardiac hemodynamic and electrophysiological parameters in patients with coronary heart disease and paroxysmal atrial fibrillation].
abstract: The study included 58 patients with CHD and paroxysmal atrial fibrillation divided into 2 groups depending on thyroid hormone and thyrotropin levels. Group 1 was comprised of 24 patients with subclinical hypothyroidism, group 2 of 18 ones with subclinical hyperthyroidism. Control group consisted of l6 patients with CHD, paroxysmal atrial fibrillation and normal thvroid function. It was shown that patients with CHD, paroxysmal atrial fibrillation and subclinical thyrotoxicosis had T3 and T4 levels 92.6 and 72.5% higher than those with subclinical hypothyroidism. Subclinical thyroid dysfunction was shown to influence hemodynamic isoelectric parameters of the heart. Therapy of paroxysmal atrial fibrillation in CHD patients with subclinical hypothyroidism or hyperthyroidism with simultaneous correction of thyroid function increases the efficacy of anti-arrhythmic therapy up to 50 and 45.9% respectively.
authors.forename: F K
authors.initials: FK
authors.lastname: Rakhmatullov
authors.forename: S V
authors.initials: SV
authors.lastname: Klimova
authors.forename: L E
authors.initials: LE
authors.lastname: Rudakova
authors.forename: S A
authors.initials: SA
authors.lastname: Pchelinsteva
authors.forename: A F
authors.initials: AF
authors.lastname: Rakhmatullov
authors.forename: A I
authors.initials: AI
authors.lastname: Khodakova
mesh_terms: D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D003327:Coronary Disease / Q000150:complications / Q000503:physiopathology*; D055724:Electrophysiological Phenomena; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications / Q000503:physiopathology*; D007037:Hypothyroidism / Q000150:complications / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D000889:Anti-Arrhythmia Agents; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine