title: Ganglioneuroblastoma arising within a retroperitoneal mature cystic teratoma.
abstract: We discuss an extremely rare case of ganglioneuroblastoma arising within a retroperitoneal mature cystic teratoma. Radiological examinations showed a cystic tumor sandwiched between the pancreas and left kidney. Surgery was scheduled because the tumor seemed to have originated from the pancreas. En-block resection of the tumor with distal pancreatectomy, splenectomy, and left adrenalectomy was performed. In terms of macroscopic appearance, the tumor mainly consisted of a unilocular cystic mass, but the presence of a smaller, solid mass was also noted within the tumor. Histopathologic examination confirmed that the cystic mass was consistent with a mature cystic teratoma of the retroperitoneum, and in addition, a ganglioneuroblastoma was evident in the solid component. Histopathologically, the ganglioneuroblastomatous area was intimately associated with dermoid tissue of the mature cystic teratoma, thus this case was diagnosed to be a mature cystic teratoma with malignant transformation. To best of our knowledge, this is the first reported case of ganglioneuroblastoma arising in a mature cystic teratoma.
authors.affiliation: Satoshi Hayama, Makoto Ohmi, Atsuya Yonemori, Takumi Yamabuki, Hitoshi Inomata, Kazuyoshi Nihei, Department of Surgery, Kushiro Red Cross Hospital, 21-14 Shineicyo, Kushiro, Hokkaido 085-8512, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hayama
authors.forename: Makoto
authors.initials: M
authors.lastname: Ohmi
authors.forename: Atsuya
authors.initials: A
authors.lastname: Yonemori
authors.forename: Takumi
authors.initials: T
authors.lastname: Yamabuki
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Inomata
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Nihei
authors.forename: Satoshi
authors.initials: S
authors.lastname: Hirano
keywords: Ganglioneuroblastoma; Malignant transformation; Mature cystic teratoma; Retroperitoneum; Surgical treatment