title: A case of recurrent psychosis during sickle cell disease crisis treated successfully with ziprasidone.
abstract: We present and follow a series of three consecutive hospitalizations of a 36-year-old, African-American male with sickle cell anemia disease who presented with sickle cell crises and a new onset psychotic episode. After multiple hospitalizations for prior episodes of sickle cell crisis-induced pain, treated with rehydration, blood transfusions, and opiate medication, this hospitalization was the first time he developed psychosis. As such, we discuss the differential diagnosis of the latter, and effective adjunctive treatment with ziprasidone.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Eastern Virginia Medical School, Norfolk, Virginia 23507, USA. spiegedr@evms.edu
authors.forename: David R
authors.initials: DR
authors.lastname: Spiegel
authors.forename: Cory
authors.initials: C
authors.lastname: Messerschmidt
authors.forename: Jerry
authors.initials: J
authors.lastname: Morewitz
authors.forename: Morakinyo
authors.initials: M
authors.lastname: Akintola
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000627:therapeutic use; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000628:therapy; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001803:Blood Transfusion / Q000379:methods; D003937:Diagnosis, Differential; D005440:Fluid Therapy / Q000379:methods; D006760:Hospitalization; D006801:Humans; D008297:Male; D010146:Pain / Q000209:etiology; D059408:Pain Management / Q000379:methods; D010879:Piperazines / Q000627:therapeutic use*; D011618:Psychotic Disorders / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D012008:Recurrence; D013844:Thiazoles / Q000627:therapeutic use*
chemical_list: D000701:Analgesics, Opioid; D014150:Antipsychotic Agents; D010879:Piperazines; D013844:Thiazoles; C092292:ziprasidone