title: Cyclodextrin-modified micellar electrokinetic chromatography for enantioseparations.
abstract: The separation of enantiomers is one of the important fields of modern analytical chemistry, especially for agrochemical and pharmaceutical products because the stereochemistry has a significant influence on the biological activities of compounds. Cyclodextrin-modified micellar electrokinetic chromatography (CD-MEKC) has become an important capillary electrophoresis mode for enantioseparations. Here, we describe an example of a CD-MEKC method using hydroxypropyl-γ-cyclodextrin as chiral selector and sodium dodecyl sulfate as micellar solution for enantioseparation of triazole fungicides and the drug econazole.
authors.affiliation: Separation Science and Technology Group (SepSTec), Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, Johor, Malaysia. wanaini@kimia.fs.utm.my
authors.forename: Wan Aini Wan
authors.initials: WA
authors.lastname: Ibrahim
authors.forename: Dadan
authors.initials: D
authors.lastname: Hermawan
authors.forename: Mohd Marsin
authors.initials: MM
authors.lastname: Sanagi
mesh_terms: D020374:Chromatography, Micellar Electrokinetic Capillary / Q000379:methods*; D004464:Econazole / Q000032:analysis / Q000737:chemistry; D005659:Fungicides, Industrial / Q000032:analysis / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D008823:Micelles; D012967:Sodium Dodecyl Sulfate / Q000737:chemistry; D013237:Stereoisomerism; D014230:Triazoles / Q000032:analysis / Q000737:chemistry; D047408:gamma-Cyclodextrins / Q000032:analysis* / Q000737:chemistry*
chemical_list: D005659:Fungicides, Industrial; D008823:Micelles; D014230:Triazoles; D047408:gamma-Cyclodextrins; C479659:hydroxypropyl-gamma-cyclodextrin; D012967:Sodium Dodecyl Sulfate; D004464:Econazole