title: The continued emergence of hantaviruses: isolation of a Seoul virus implicated in human disease, United Kingdom, October 2012.
abstract: Following a suspected case of hantavirus in a patientsuffering from acute kidney injury, rodents fromthe patient’s property in Yorkshire and the Humber,United Kingdom (UK) were screened for hantaviruses.Hantavirus RNA was detected via RT-PCR in two Rattusnorvegicus. Complete sequencing and phylogeneticanalysis established the virus as a Seoul hantavirus,which we have provisionally designated as strainHumber. This is the first hantavirus isolated from wildrodents in the UK and confirms the presence of a pathogenicSeoul virus in Europe.
authors.affiliation: Virology and Pathogenesis, Microbiology Services, Health Protection Agency, Porton Down, Wiltshire, United Kingdom. lisa.jameson@hpa.org.uk
authors.forename: L J
authors.initials: LJ
authors.lastname: Jameson
authors.forename: C H
authors.initials: CH
authors.lastname: Logue
authors.forename: B
authors.initials: B
authors.lastname: Atkinson
authors.forename: N
authors.initials: N
authors.lastname: Baker
authors.forename: S E
authors.initials: SE
authors.lastname: Galbraith
authors.forename: M W
authors.initials: MW
authors.lastname: Carroll
authors.forename: T
authors.initials: T
authors.lastname: Brooks
authors.forename: R
authors.initials: R
authors.lastname: Hewson
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis* / Q000821:virology; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D021821:Communicable Diseases, Emerging / Q000821:virology; D004197:Disease Reservoirs; D018778:Hantavirus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D010802:Phylogeny; D012367:RNA, Viral / Q000032:analysis* / Q000235:genetics; D051381:Rats; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012376:Rodent Diseases; D029263:Seoul virus / Q000235:genetics / Q000302:isolation & purification*; D017422:Sequence Analysis, DNA; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D000914:Antibodies, Viral; D012367:RNA, Viral