title: Comparative study of prevalence of metabolic syndrome in bipolar disorder and schizophrenia from North India.
abstract: BACKGROUND
  Very few studies have compared the prevalence of metabolic syndrome (MS) between patients with bipolar disorder and schizophrenia.
  
  
  OBJECTIVE
  The study aimed to compare the prevalence of MS in patients with bipolar disorder and schizophrenia.
  
  
  METHODS
  By consecutive sampling, 126 patients with schizophrenia and 72 patients with bipolar disorder admitted to a psychiatry inpatient unit were evaluated for the presence of MS using the criteria of International Diabetes Federation (IDF) and modified National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP-III). A control group of 50 healthy subjects was used to represent the general prevalence of MS in the community.
  
  
  RESULTS
  In the bipolar disorders group, 40 patients (55.55%) fulfilled IDF criteria and 45 (62.5%) satisfied modified NCEP ATP-III criteria for MS. These figures were significantly higher than those for the schizophrenia group (34.1% IDF and 36.5% modified NCEP ATP-III criteria). Prevalence of MS was 6% in the healthy control group and significantly less than both schizophrenia and bipolar disorder group.
  
  
  CONCLUSIONS
  In the sample studied, prevalence of MS is significantly higher in bipolar disorder compared with schizophrenia. The prevalence of MS in both the clinical groups was significantly higher than the healthy control group.
authors.affiliation: Department of Psychiatry, Postgraduate Institute of Medical Education & Research , Chandigarh 160012 , India.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Grover
authors.forename: Naresh
authors.initials: N
authors.lastname: Nebhinani
authors.forename: Subho
authors.initials: S
authors.lastname: Chakrabarti
authors.forename: Ajit
authors.initials: A
authors.lastname: Avasthi
authors.forename: Parmanand
authors.initials: P
authors.lastname: Kulhara
authors.forename: Debasish
authors.initials: D
authors.lastname: Basu
authors.forename: Surendra Kumar
authors.initials: SK
authors.lastname: Mattoo
authors.forename: Savita
authors.initials: S
authors.lastname: Malhotra
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000150:complications / Q000453:epidemiology*; D002784:Cholesterol / Q000097:blood*; D035061:Control Groups; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D038801:International Classification of Diseases; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000453:epidemiology*; D008875:Middle Aged; D015995:Prevalence; D012559:Schizophrenia / Q000150:complications / Q000453:epidemiology*; D012959:Socioeconomic Factors; D062606:Tertiary Care Centers
chemical_list: D002784:Cholesterol