title: From genes to characteristics of multiple sclerosis.
abstract: Multiple sclerosis (MS) is an inflammatory, demyelinating heterogeneous disease of the central nervous system, probably caused by an interaction of common genetic and environmental factors. Much progress has been made through the last few years in genetic studies of MS, and a growing list of genetic risk factors is now available. Biobanking and large collaborations have been prerequisites for this research, and detailed genetic and molecular characterizations are underway, with hopes for to translating new knowledge about MS pathogenesis and characteristics of the disease to personalized, better treatment options for each patient with MS.
authors.affiliation: Department of Neurology, Oslo University Hospital, Oslo, Norway. h.f.harbo@medisin.uio.no
authors.forename: H F
authors.initials: HF
authors.lastname: Harbo
authors.forename: I-L
authors.initials: IL
authors.lastname: Mero
mesh_terms: D018070:Biological Specimen Banks; D002490:Central Nervous System / Q000503:physiopathology; D003711:Demyelinating Diseases / Q000235:genetics / Q000276:immunology; D020022:Genetic Predisposition to Disease; D006801:Humans; D009103:Multiple Sclerosis / Q000235:genetics* / Q000276:immunology / Q000628:therapy*; D012307:Risk Factors; D016896:Treatment Outcome