title: A rapidly recurring cutaneous xanthogranuloma-like histiocytic tumor: a diagnostic challenge.
abstract: Xanthogranuloma (XG) is a benign cutaneous histiocytic tumor occurring mainly in young children. Onset in adulthood is rarely observed. We encountered an unusual case of an XG-like cutaneous tumor on the scalp of a 50-year-old man. The tumor recurred with multiple satellite nodules soon after surgical excision. This unusual clinical behavior has not previously been described for XG and caused a diagnostic challenge; it was unclear whether the tumor was an atypical XG or a malignant dermal tumor mimicking an XG. Our analyses favored an XG-like dermal histiocytic tumor. A longer follow-up and reports of similar cases will reveal its true nature.
authors.affiliation: Department of Dermatology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kwei Shan, Taoyuan, Taiwan.
authors.forename: Pei-Han
authors.initials: PH
authors.lastname: Kao
authors.forename: Li-yu
authors.initials: LY
authors.lastname: Lee
authors.forename: Yi-Fang
authors.initials: YF
authors.lastname: Wu
authors.forename: Chih-Hsun
authors.initials: CH
authors.lastname: Yang
authors.forename: Tseng-tong
authors.initials: TT
authors.lastname: Kuo
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D006099:Granuloma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D015620:Histiocytic Disorders, Malignant / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012086:Reoperation; D012535:Scalp / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome; D014973:Xanthomatosis / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor