title: Considerations on afterload management for patients with centrifugal ventricular assist devices.
abstract: This case report illustrates the challenges in managing patients with centrifugal ventricular assist devices (VADs). As these devices have evolved, their physical properties have changed, impacting patient management. Levitated centrifugal pumps have a non-linear response to afterloads. The device output will decrease significantly in the presence of high systemic vascular resistance. Blood pressure control is integral to the management of patients in the immediate and later postoperative period.
authors.affiliation: Department of Anesthesiology, University of Michigan, Ann Arbor, MI 48109-5861, USA. yassere@med.umich.edu
authors.forename: Yasser
authors.initials: Y
authors.lastname: Kouatli
authors.forename: Sean
authors.initials: S
authors.lastname: Neill
authors.forename: Frank
authors.initials: F
authors.lastname: Pagani
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure; D004232:Diuretics / Q000627:therapeutic use; D005260:Female; D006333:Heart Failure / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006353:Heart-Assist Devices / Q000009:adverse effects; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D008875:Middle Aged; D011474:Prosthesis Design; D011654:Pulmonary Edema / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D013318:Stroke Volume; D016896:Treatment Outcome; D014655:Vascular Resistance; D016277:Ventricular Function, Left
chemical_list: D000959:Antihypertensive Agents; D004232:Diuretics