title: Pluripotent genes in avian stem cells.
abstract: Embryonic stem (ES) cells were first isolated in 1981 in the mouse from the in vitro proliferation of the inner cell mass of a 3.5 days post-coitum (dpc) blastocyst. Later on, epiblast stem cells (EpiSC) were identified from in vitro culture of the epiblast of a 6.5 dpc mouse embryo, leading to the concept of naïve and primed stem cells. Among non-mammalian species, ES cells have been characterized both in birds and fish; here, we focus on cells derived from chicken and the pluripotent associated markers such as OCT4, SOX2, NANOG, and KLF, previously identified in mammalian cells. In this review, we present both published and original data regarding the involvement of those pluripotent associated genes in the ES cells and early embryo of chicken.
authors.affiliation: Stem Cell and Brain Research Institute, INSERM U846, Bron, France.
authors.forename: Christian
authors.initials: C
authors.lastname: Jean
authors.forename: Pauline
authors.initials: P
authors.lastname: Aubel
authors.forename: Clément
authors.initials: C
authors.lastname: Soleihavoup
authors.forename: Frantz
authors.initials: F
authors.lastname: Bouhallier
authors.forename: Sophie
authors.initials: S
authors.lastname: Voisin
authors.forename: Fabrice
authors.initials: F
authors.lastname: Lavial
authors.forename: Bertrand
authors.initials: B
authors.lastname: Pain
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D049109:Cell Proliferation; D002642:Chick Embryo; D047108:Embryonic Development; D005347:Fibroblasts / Q000166:cytology / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000235:genetics / Q000378:metabolism; D006801:Humans; D051741:Kruppel-Like Transcription Factors / Q000235:genetics / Q000378:metabolism; D051379:Mice; D000071317:Nanog Homeobox Protein; D050814:Octamer Transcription Factor-3 / Q000235:genetics / Q000378:metabolism*; D039904:Pluripotent Stem Cells / Q000166:cytology*; D055748:SOXB1 Transcription Factors / Q000235:genetics / Q000378:metabolism*; D015533:Transcriptional Activation
chemical_list: D018398:Homeodomain Proteins; D051741:Kruppel-Like Transcription Factors; C486780:NANOG protein, human; D000071317:Nanog Homeobox Protein; D050814:Octamer Transcription Factor-3; C494174:Pou5f1 protein, mouse; D055748:SOXB1 Transcription Factors