title: Primary pulmonary angiosarcoma, an exceptional neoplasm with a poor prognosis: reports of two cases and review of the literature.
abstract: Primary pulmonary angiosarcoma is a rare type of malignant vascular tumour characterised by proliferation of tumour cells with endothelial features. Up to date, only sixteen cases have been reported in English Literature. Treatment modalities vary from none to surgery, chemotherapeutic regimens, radiotherapy or immunotherapy, but none of them have been shown to be effective. Unfortunately, these tumours are usually very aggressive and overall mortality is very high. We present two cases of patients with a diagnosis of primary pulmonary angiosarcoma, the largest case series ever described, and a review of the scientific literature.
authors.affiliation: Department of Thoracic Surgery, Vigo University Clinical Hospital, Pizarro No 22, 36204, Vigo, Pontevedra, Spain, andresobca@hotmail.com.
authors.forename: Gerardo Andrés
authors.initials: GA
authors.lastname: Obeso Carillo
authors.forename: Eva María
authors.initials: EM
authors.lastname: García Fontán
authors.forename: Miguel Ángel
authors.initials: MÁ
authors.lastname: Cañizares Carretero
authors.forename: Alberto
authors.initials: A
authors.lastname: Pérez Pedrosa
mesh_terms: D000328:Adult; D017809:Fatal Outcome; D006394:Hemangiosarcoma / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011379:Prognosis