title: New monoterpene lactones from Actaea cimicifuga.
abstract: Three new monoterpene lactones, cimicifugolides A-C (1-3), along with a known one (4), were identified from the dried rhizome of Actaea cimicifuga L. that was used as traditional Chinese medicine for thousands of years with the Chinese common name of shengma. The structures of the new isolates were established using spectroscopic methods, including NMR, mass, UV, and IR spectra. The inhibition activity of compounds 1, 2, and 4 against pancreatic lipase was evaluated.
authors: College of Life and Environmental Sciences, Minzu University of China, Beijing, People's Republic of China.
authors: Li-Juan
authors: LJ
authors: Ma
authors: Yue-Hu
authors: YH
authors: Wang
authors: Gui-Hua
authors: GH
authors: Tang
authors: Ye-Ling
authors: YL
authors: Wang
authors: Chunhui
authors: C
authors: Ma
authors: Keyvan
authors: K
authors: Dastmalchi
authors: Edward J
authors: EJ
authors: Kennelly
authors: Chun-Lin
authors: CL
authors: Long
mesh_terms: D031842:Actaea / Q000737:chemistry*; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D008049:Lipase / Q000037:antagonists & inhibitors*; D009682:Magnetic Resonance Spectroscopy; D008516:Medicine, Chinese Traditional; D015394:Molecular Structure; D039821:Monoterpenes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry; D027343:Rhizome / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D004791:Enzyme Inhibitors; D007783:Lactones; D039821:Monoterpenes; D008049:Lipase