title: Lyme disease: review.
abstract: Lyme disease is a multi-organ animal-borne disease, caused by spirochetes of Borrelia burgdorferi (Bb), which typically affect the skin, nervous system, musculoskeletal system and heart. A history of confirmed exposure to tick bites, typical signs and symptoms of Lyme borreliosis and positive tests for anti-Bb antibodies, are the basis of a diagnosis. A two-step diagnosis is necessary: the first step is based on a high sensitivity ELISA test with positive results confirmed by a more specific Western blot assay. Antibiotic therapy is curative in most cases, but some patients develop chronic symptoms, which do not respond to antibiotics. The aim of this review is to summarize our current knowledge of the symptoms, clinical diagnosis and treatment of Lyme borreliosis.
authors: Chair of Gastroenterology, Hepatology and Infectious Diseases, Jagiellonian University Medical College, Krakow, Poland.
authors: Grażyna
authors: G
authors: Biesiada
authors: Jacek
authors: J
authors: Czepiel
authors: Maciej R
authors: MR
authors: Leśniak
authors: Aleksander
authors: A
authors: Garlicki
authors: Tomasz
authors: T
authors: Mach
keywords: Lyme borreliosis; borreliosis; tick