title: Intraductal polypoid lipid-rich neuroendocrine tumor of the pancreas with entrapped ductules: case report and review of the literature.
abstract: Pancreatic neuroendocrine tumors of the main pancreatic duct are rare and usually small due to symptoms of pancreatic duct obstruction. We present a case of a large (3 cm), well-differentiated (G1) lipid-rich polypoid neuroendocrine tumor of the pancreas completely occluding the main pancreatic duct with non-neoplastic-entrapped ductules and CK19 positivity. Clinical, radiological, gross, microscopic, immunohistochemical, and ultrastructural findings are discussed. The literature pertaining to the unique features of this case is reviewed including clinical and pathologic pitfalls and the possible etiologic and prognostic significance of these findings.
authors: Department of Pathology, Mount Sinai School of Medicine, One Gustave L Levy Place, 1194, New York, NY 10029, USA. jaclyn.hechtman@mountsinai.org
authors: Jaclyn Frances
authors: JF
authors: Hechtman
authors: Bernardo
authors: B
authors: Franssen
authors: Daniel M
authors: DM
authors: Labow
authors: Ronald E
authors: RE
authors: Gordon
authors: Christopher J
authors: CJ
authors: DiMaio
authors: Eric J
authors: EJ
authors: Wilck
authors: Gonzalo
authors: G
authors: Carrasco-Avino
authors: Hongfa
authors: H
authors: Zhu
mesh_terms: D015415:Biomarkers; D021441:Carcinoma, Pancreatic Ductal / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D050356:Lipid Metabolism / Q000502:physiology*; D008854:Microscopy, Electron; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000378:metabolism* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D015415:Biomarkers