title: Inflammatory myofibroblastic tumor successfully treated with chemotherapy and nonsteroidals: a case report.
abstract: Inflammatory myofibroblastic tumor (IMT) occurring at retroperitoneal sites has rarely been reported. We report the case of a previously well 14-year-old girl with no history of abdominal disease whose past medical history and family tumor history were unremarkable. She complained of intermittent abdominal pain for one month. An abdominal mass was found on physical examination and abdominal contrast-enhanced computed tomography (CT) showed a hypodense soft mass, the size and location of which suggested a well delineated retroperitoneal tumor surrounding the superior mesenteric vessels measuring 3.3 cm × 4.5 cm × 4.5 cm with enlarged lymph nodes. The patient underwent an exploratory laparotomy followed by biopsy and was subsequently diagnosed with retroperitoneal IMT. She was successfully treated with postoperative chemotherapy and oral diclofenac sodium. Following completion of therapy the mass was no longer palpable and no longer visible on CT scanning. The use of methotrexate and cisplatin for aggressive myofibroblastic tumors is also reviewed.
authors: Department of General Surgery, Chao Yang Hospital, Affiliated to Capital Medical University, Beijing 100020, China.
authors: Yun-Lu
authors: YL
authors: Tao
authors: Zhen-Jun
authors: ZJ
authors: Wang
authors: Jia-Gang
authors: JG
authors: Han
authors: Ping
authors: P
authors: Wei
mesh_terms: D000008:Abdominal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*; D000293:Adolescent; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001706:Biopsy; D002945:Cisplatin / Q000627:therapeutic use; D004008:Diclofenac / Q000627:therapeutic use; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D006801:Humans; D007249:Inflammation / Q000188:drug therapy; D008727:Methotrexate / Q000627:therapeutic use; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000970:Antineoplastic Agents; D004008:Diclofenac; D002945:Cisplatin; D008727:Methotrexate
keywords: Chemotherapy; Inflammatory myofibroblastic tumor; Nonsteroidals; Retroperitoneum; Therapy