title: Insight in stable schizophrenia: relations with psychopathology and cognition.
abstract: OBJECTIVE
  This study evaluated the relationship among insight, sociodemographic and clinical variables, symptoms and cognitive functions in a population of outpatients with stable schizophrenia, in order to identify possible contributing factors to awareness.
  
  
  METHODS
  Two-hundred and seventy-six consecutive outpatients with stable schizophrenia were enrolled in a cross-sectional study. All subjects were assessed by psychiatric scales and interview, and a wide neuropsychological battery. A factor analysis was performed to identify cognitive factors and multiple regression analyses were executed to test the contribution of variables considered to insight.
  
  
  RESULTS
  Our results showed that positive and negative symptoms, executive functions, verbal memory-learning were contributors of awareness of mental illness; positive and negative symptoms explained variability in awareness of the need for treatment; positive symptoms and executive functions contributed to awareness of the social consequences of disorder.
  
  
  CONCLUSIONS
  These results suggested that insight was partially influenced by positive and negative symptoms and by cognitive functions. A complex system of overlapping variables may underlie impaired insight, contributing to a different extent to specific dimensions of poor insight in patients with stable schizophrenia.
authors: Department of Neuroscience, Psychiatric Section, University of Turin, Via Cherasco 11, 10126 Turin, Italy.
authors: Cinzia
authors: C
authors: Mingrone
authors: Paola
authors: P
authors: Rocca
authors: Filomena
authors: F
authors: Castagna
authors: Cristiana
authors: C
authors: Montemagni
authors: Monica
authors: M
authors: Sigaudo
authors: Mara
authors: M
authors: Scalese
authors: Giuseppe
authors: G
authors: Rocca
authors: Filippo
authors: F
authors: Bogetto
mesh_terms: D000328:Adult; D001364:Awareness; D003071:Cognition; D003430:Cross-Sectional Studies; D056344:Executive Function; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory; D008875:Middle Aged; D009483:Neuropsychological Tests; D011340:Problem Solving; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics; D012565:Schizophrenic Psychology