title: [Immune-mediated epilepsy and encephalopathy].
abstract: During the last decade new knowledge on immune-mediated disorders of the grey substance of the central nervous system (CNS) has been generated. These conditions are associated with seizures in approximately 80% of cases and often present as drug-resistant epilepsies. The discovery of autoantibodies against neural surface antigens was essential for the identification of these disorders. Immune-mediated epilepsies often respond poorly to antiepileptic drugs; however, they do respond in many cases to immunological therapy which offers a chance of overcoming resistance to antiepileptic drugs by immunological treatment.
authors: Epilepsie-Zentrum Bethel, Krankenhaus Mara, Maraweg 17-21, 33617 Bielefeld, Deutschland. corinna.kramme@mara.de
authors: C
authors: C
authors: Kramme
authors: C G
authors: CG
authors: Bien
mesh_terms: D001323:Autoantibodies / Q000276:immunology*; D020274:Autoimmune Diseases of the Nervous System / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy*; D004679:Encephalomyelitis / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy*; D004827:Epilepsy / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy*; D006801:Humans; D007167:Immunotherapy / Q000639:trends
chemical_list: D001323:Autoantibodies