title: Effects of exogenous glycosaminoglycans on the histological structure of the rat bladder in experimental cystitis.
abstract: The protective effects of a complex glycosaminoglycan preparation in doses of 50 and 100 mg/kg were studied in experimental cystitis induced in rats by administration of 9% acetic acid. Daily glycosaminoglycan intake for 2 weeks before intrabladder injection of acetic acid resulted in a less severe injury to the bladder mucosa in comparison with controls receiving no glycosaminoglycans.
authors: St. Petersburg State Academy of Veterinary Medicine, Russia. vesob@mail.ru
authors: V E
authors: VE
authors: Sobolev
mesh_terms: D019342:Acetic Acid; D000818:Animals; D003556:Cystitis / Q000188:drug therapy* / Q000517:prevention & control*; D004195:Disease Models, Animal; D005260:Female; D006025:Glycosaminoglycans / Q000008:administration & dosage*; D009092:Mucous Membrane / Q000187:drug effects / Q000473:pathology; D051381:Rats; D001743:Urinary Bladder / Q000187:drug effects* / Q000473:pathology
chemical_list: D006025:Glycosaminoglycans; D019342:Acetic Acid