title: Local and systemic hemostatics as an adjunct to control bleeding in trauma.
abstract: Although surgical and angiointervention techniques remain the cornerstone for the management of severe bleeding after trauma, adjunct therapeutic strategies such as local or systemic hemostatic agents can play an important role. This article reviews the role and efficacy of the available  hemostatic agents.
authors: Department of Surgery, Nicosia General Hospital, Nicosia, Cyprus. chr.georgiou@traumangh.com
authors: Chrysanthos
authors: C
authors: Georgiou
authors: Kyriakos
authors: K
authors: Neofytou
authors: Demetrios
authors: D
authors: Demetriades
mesh_terms: D000287:Administration, Topical; D002483:Cellulose, Oxidized / Q000627:therapeutic use; D048271:Chitosan / Q000627:therapeutic use; D003131:Combined Modality Therapy; D015942:Factor VIIa / Q000627:therapeutic use; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use; D006470:Hemorrhage / Q000188:drug therapy* / Q000209:etiology / Q000628:therapy; D006489:Hemostatic Techniques; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D011994:Recombinant Proteins / Q000627:therapeutic use; D014014:Tissue Adhesives / Q000627:therapeutic use; D014148:Tranexamic Acid / Q000627:therapeutic use; D014947:Wounds and Injuries / Q000150:complications*; D017641:Zeolites / Q000627:therapeutic use
chemical_list: D002483:Cellulose, Oxidized; D015718:Fibrin Tissue Adhesive; D006490:Hemostatics; D011994:Recombinant Proteins; D014014:Tissue Adhesives; D017641:Zeolites; D014148:Tranexamic Acid; C013695:Surgicel; D048271:Chitosan; C103587:recombinant FVIIa; D015942:Factor VIIa