title: Metastatic basal cell carcinoma: report of a case and review of the literature.
abstract: BACKGROUND
  Metastatic basal cell carcinoma (MBCC) is defined as primary cutaneous basal cell carcinoma (BCC) that spreads to distant sites as histologically similar metastatic deposits of BCC. BCCs are semimalignant, destructive, and invasive. Metastases are very rare, with an incidence of 0.0028%-0.5%.
  
  
  METHODS
  A female patient with Gorlin-Goltz syndrome and a rare case of a basal cell carcinoma with an additional regional lymph node metastasis is presented.
  
  
  CONCLUSIONS
  This case highlights the importance of a multidisciplinary approach to and frequent monitoring of patients with Gorlin-Goltz syndrome. Early diagnosis and surgical treatment are still the treatment of first choice.
authors: Department of Craniomexillofacial and Oral Surgery, University Hospital Zurich. Electronic address: stephanie.moser@zzm.uzh.ch.
authors: Stephanie
authors: S
authors: Moser
authors: Department of Craniomexillofacial and Oral Surgery, University Hospital Zurich.
authors: Jan
authors: J
authors: Borm
authors: Institute of Surgical Pathology, University of Zurich.
authors: Daniela
authors: D
authors: Mihic-Probst
authors: Department of Craniomaxillofacial Surgery, University Hospital Zurich.
authors: Christine
authors: C
authors: Jacobsen
authors: Department of Craniomaxillofacial Surgery, University Hospital Zurich.
authors: Astrid L
authors: AL
authors: Kruse Gujer
mesh_terms: D001478:Basal Cell Nevus Syndrome / Q000473:pathology* / Q000601:surgery; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis / Q000473:pathology*; D008875:Middle Aged