title: Role of adenosine in diabetic retinopathy.
abstract: In diabetic retinopathy (DR), abnormalities in vascular and neuronal function are closely related to the local production of inflammatory mediators whose potential source is microglia. Adenosine and its receptors have been shown to possess anti-inflammatory properties that have only recently been studied in DR. Here, we review recent studies that determined the roles of adenosine and its associated proteins, including equilibrative nucleoside transporters, adenosine receptors, and underlying signaling pathways in retinal complications associated with diabetes.
authors: Department of Ophthalmology, Georgia Health Sciences University, 1120 15th Street, Augusta, GA 30912 USA.
authors: Gregory I
authors: GI
authors: Liou
authors: Saif
authors: S
authors: Ahmad
authors: Mohammad
authors: M
authors: Naime
authors: Nadeem
authors: N
authors: Fatteh
authors: Ahmed S
authors: AS
authors: Ibrahim
keywords: Adenosine; Adenosine receptors; Cannabinoids; Diabetic retinopathy; Microglia