title: Visual outcome and changes in corneal endothelial cell density following aphakic iris-fixated intraocular lens implantation in pediatric eyes with subluxated lenses.
abstract: OBJECTIVE
  To evaluate the visual outcome and corneal endothelial cell density after Artisan aphakic intraocular lens (IOL) implantation (Ophtec, Groningen, the Netherlands) in pediatric eyes with subluxated lenses.
  
  
  METHODS
  Artisan aphakic IOLs were implanted in 18 eyes of 11 children with subluxated lenses. Idiopathic subluxations and ectopia lentis due to Marfan syndrome were included, whereas subluxations due to trauma or buphthalmos were excluded. Best-corrected visual acuity (BCVA) and endothelial cell density were monitored. Mean postoperative BCVA and endothelial cell density at last follow-up visit were calculated.
  
  
  RESULTS
  The age of children at the time of Artisan aphakic IOL implantation ranged from 8 to 16 years (mean: 11.58 ± 2.9 years). Mean follow-up was 9.12 ± 4.30 months. Mean postoperative logarithm of the minimum angle of resolution BCVA was 0.26 ± 0.13 (P = .001) and mean postoperative endothelial cell density was 2,860 ± 435 cells/mm(2) (P = .000). Mean endothelial cell loss was 17.1%.
  
  
  CONCLUSIONS
  Artisan aphakic IOL implantation is a safe surgical choice in the management of ectopia lentis in the pediatric age group. It has minimal complications and is less traumatic to pediatric eyes. However, long-term follow-up of these children is required.[J Pediatr Ophthalmol Strabismus 2013;50(3):178-182.].
authors: Department of Pediatric Ophthalmology and Strabismus (SNS), Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan. sorathnoorani@yahoo.com
authors: Sorath Noorani
authors: SN
authors: Siddiqui
authors: Ayesha
authors: A
authors: Khan
mesh_terms: D000293:Adolescent; D001035:Aphakia / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D002452:Cell Count; D002648:Child; D004728:Endothelium, Corneal / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007498:Iris / Q000601:surgery*; D007906:Lens Subluxation / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D007910:Lenses, Intraocular; D008297:Male; D011184:Postoperative Period; D011446:Prospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology*