title: [Analysis of causative factors for lower limb deep vein thrombosis complicated with artery pulmonary embolism in orthopedics patients].
abstract: OBJECTIVE
  To explore the causative factors of lower limb deep vein thrombosis complicated with pulmonary artery embolism in orthopedics patients.
  
  
  METHODS
  The clinical manifestations and causes of thrombosis defluxion of pulmonary artery embolism patients whose diagnosis were confirmed by computed tomography pulmonary angiography (CTPA) during May 2009-May 2012 were retrospectively analyzed.
  
  
  RESULTS
  Among 45 cases of CTPA-confirmed pulmonary artery embolism patients, 5 patients had no obvious clinical manifestation. The initial symptoms included chest stuffiness and dyspnea (n = 9) and cough (n = 8). And the major causes of thrombosis defluxion were early postoperative mobilization (n = 11), postoperative functional exercise (n = 9), rollover or defecation in bed (n = 7), sneezing (n = 2) and unknown causes (n = 14).
  
  
  CONCLUSIONS
  The patients with lower limb deep vein thrombosis have a high risk of thrombosis defluxion during unstable period. Despite adequate anticoagulation, early mobilization and functional exercise are likely to cause thrombosis defluxion and lead to pulmonary artery embolism.
authors: Department of Vascular Surgery, Beijing Jishuitan Hospital, Beijing 100035, China.
authors: Peng
authors: P
authors: Jiang
authors: Jian-long
authors: JL
authors: Liu
authors: Wei
authors: W
authors: Jia
authors: Xuan
authors: X
authors: Tian
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000009:adverse effects*; D011655:Pulmonary Embolism / Q000150:complications*; D012189:Retrospective Studies; D020246:Venous Thrombosis / Q000209:etiology*; D055815:Young Adult