title: Acaricidal activity of Lippia gracilis essential oil and its major constituents on the tick Rhipicephalus (Boophilus) microplus.
abstract: The present study aimed to evaluate the activity of Lippia gracilis Schauer essential oil obtained from different L. gracilis genotypes and their major components, carvacrol and thymol against Rhipicephalus (Boophilus) microplus (cattle tick) larvae and engorged females. The larval test was performed parallel to the adult immersion test for engorged females for four L. gracilis genotypes. Similar tests were further performed for their major compounds carvacrol and thymol. Carvacrol (LC50 of 0.22 and 4.46 mg/mL, to larvae and engorged females, respectively) was more efficient than thymol (LC50 of 3.86 and 5.50 mg/mL, to larvae and engorged females, respectively). The lethal concentrations obtained for the isolated essential oil from genotypes LGRA-201 against larvae (1.31 mg/mL) and LGRA-106 against engorged females (4.66 mg/mL) confirmed the acaricidal activity of L. gracilis essential oil and its effectiveness in controlling the southern cattle tick.
authors: Agronomy Department, Federal University of Sergipe, Av. Marechal Rondon S/N, CEP 49100-000, São Cristóvão, SE, Brazil.
authors: Elizangela Mércia de Oliveira
authors: EM
authors: Cruz
authors: Livio Martins
authors: LM
authors: Costa
authors: Jessika Andreza Oliveira
authors: JA
authors: Pinto
authors: Darlisson de Alexandria
authors: Dde A
authors: Santos
authors: Sandra Alves
authors: SA
authors: de Araujo
authors: Maria de Fátima
authors: Mde F
authors: Arrigoni-Blank
authors: Leandro
authors: L
authors: Bacci
authors: Péricles Barreto
authors: PB
authors: Alves
authors: Sócrates Cabral de Holanda
authors: SC
authors: Cavalcanti
authors: Arie Fitzgerald
authors: AF
authors: Blank
mesh_terms: D056810:Acaricides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D002417:Cattle; D000081007:Cymenes; D005260:Female; D007814:Larva / Q000187:drug effects; D007928:Lethal Dose 50; D032411:Lippia / Q000737:chemistry* / Q000145:classification / Q000235:genetics; D039821:Monoterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D009822:Oils, Volatile / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry; D010938:Plant Oils / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal; D048494:Rhipicephalus / Q000187:drug effects*; D013943:Thymol / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D013984:Tick Infestations / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D056810:Acaricides; D000081007:Cymenes; D039821:Monoterpenes; D009822:Oils, Volatile; D010938:Plant Oils; D013943:Thymol; C073316:carvacrol