title: Hepatoblastoma evaluated by 18F-fluoromethyl choline PET/CT.
abstract: Hepatoblastoma is a rare carcinoma mostly seen in children. Neoadjuvant chemotherapy followed by resection and adjuvant chemotherapy is the optimal treatment. We present the case of an 18-year-old woman who presented with abdominal pain, nausea, bloating, and fatigue. MRI showed 3 hepatic lesions with high signal intensity on arterial phase T1-weighted images and slight washout on the late phase, suggestive for hepatocellular carcinoma. Laboratory examinations revealed plasma α-feto-protein of 114,245 μg/L. Subsequent baseline and posttreatment F-fluoromethyl choline PET/CT were performed to possibly evaluate extent of the disease and assess disease response after neoadjuvant chemotherapy.
authors: Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. M.Bieze@amc.uva.nl
authors: Matthanja
authors: M
authors: Bieze
authors: Thomas M
authors: TM
authors: van Gulik
authors: Roelof J
authors: RJ
authors: Bennink
mesh_terms: D000293:Adolescent; D002794:Choline / Q000031:analogs & derivatives*; D005260:Female; D018197:Hepatoblastoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
chemical_list: C516370:fluoromethylcholine; D002794:Choline