title: Impact of pharmacy technician-centered medication reconciliation on optimization of antiretroviral therapy and opportunistic infection prophylaxis in hospitalized patients with HIV/AIDS.
abstract: OBJECTIVE
  This study aimed to examine the role of a pharmacy technician-centered medication reconciliation (PTMR) program in optimization of medication therapy in hospitalized patients with HIV/AIDS.
  
  
  METHODS
  A chart review was conducted for all inpatients that had a medication reconciliation performed by the PTMR program. Adult patients with HIV and antiretroviral therapy (ART) and/or the opportunistic infection (OI) prophylaxis listed on the medication reconciliation form were included. The primary objective is to describe the (1) number and types of medication errors and (2) the percentage of patients who received appropriate ART. The secondary objective is a comparison of the number of medication errors between standard mediation reconciliation and a pharmacy-led program.
  
  
  RESULTS
  In the PTMR period, 55 admissions were evaluated. In all, 50% of the patients received appropriate ART. In 27of the 55 admissions, there were 49 combined ART and OI-related errors. The most common ART-related errors were drug-drug interactions. The incidence of ART-related medication errors that included drug-drug interactions and renal dosing adjustments were similar between the pre-PTMR and PTMR groups (P = .0868). Of the 49 errors in the PTMR group, 18 were intervened by a medication reconciliation pharmacist.
  
  
  CONCLUSIONS
  A PTMR program has a positive impact on optimizing ART and OI prophylaxis in patients with HIV/AIDS.
authors: Philadelphia College of Pharmacy, University of the Sciences, Philadelphia, PA, USA.
authors: Laura A
authors: LA
authors: Siemianowski
authors: Sanchita
authors: S
authors: Sen
authors: Jomy M
authors: JM
authors: George
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000517:prevention & control*; D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D004347:Drug Interactions; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008508:Medication Errors / Q000706:statistics & numerical data; D059065:Medication Reconciliation; D008875:Middle Aged; D010596:Pharmacy Technicians
chemical_list: D044966:Anti-Retroviral Agents
keywords: HIV/AIDS; antiretroviral; medication discrepancies; medication errors; medication reconciliation; pharmacy technician