title: Severe CMV complication following maintenance therapy with rituximab.
abstract: Cytomegalovirus (CMV) encephalitis is a rare infection that immunodeficient patients, mainly where HIV-positive, may suffer from. Several cases were described when complications with the treatment with monoclonal antibodies, like rituximab, for malignant lymphomas. We will describe here the case of a patient, who has developed CMV gastritis, then CMV encephalitis after the treatment of a CLL with a chemotherapy and maintenance therapy with rituximab.
authors: Department of Clinical Haematology, Institute of Cancerology and Hematology, University Hospital Brest, Brest, France. lenaig.leclech@hotmail.fr
authors: Lenaïg
authors: L
authors: Le Clech
authors: Jean-Christophe
authors: JC
authors: Ianotto
authors: Isabelle
authors: I
authors: Quintin-Roue
authors: Adrian
authors: A
authors: Tempescul
mesh_terms: D000368:Aged; D058846:Antibodies, Monoclonal, Murine-Derived / Q000009:adverse effects* / Q000627:therapeutic use; D000914:Antibodies, Viral / Q000032:analysis*; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy*; D008297:Male; D000069283:Rituximab; D012720:Severity of Illness Index
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D000914:Antibodies, Viral; D000970:Antineoplastic Agents; D000069283:Rituximab