title: 18F-fluorocholine uptake in a case of adrenal incidentaloma: possible diagnostic pitfall or potential tool for adrenocortical tumors characterization?
abstract: The understanding of radiotracer's physiological biodistribution as well as the potential source of false-positive results is crucial for an accurate diagnostic interpretation of (18)F-fluorocholine PET/CT examination in patients with prostate cancer. We illustrate the results of whole-body (18)F-fluorocholine PET/CT in a 79-year-old man with biochemical suspicion of prostate adenocarcinoma relapse. PET/CT study showed a focally increased (18)F-fluorocholine uptake, characterizing an incidentally found adrenocortical adenoma. Finally, we draw oncologists' attention to the possible false-positive results of (18)F-fluorocholine PET related to benign and unsuspected adrenocortical lesions in patients with a history of prostate malignancy.
authors: Service de Biophysique et Médecine Nucléaire, Hôpitaux Universitaires de Strasbourg, Strasbourg, France. alessio.imperiale@chru-strasbourg.fr
authors: Alessio
authors: A
authors: Imperiale
authors: José Facundo
authors: JF
authors: Cabral
authors: Edmond
authors: E
authors: Rust
authors: Guadalupe
authors: G
authors: Flores-Turk
authors: Caroline
authors: C
authors: Renard
authors: Fabrice
authors: F
authors: Hubele
authors: Julien
authors: J
authors: Detour
authors: Hervé
authors: H
authors: Lang
authors: Afshin
authors: A
authors: Gangi
authors: Izzie-Jacques
authors: IJ
authors: Namer
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D000368:Aged; D001692:Biological Transport; D002794:Choline / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D005189:False Positive Reactions; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
chemical_list: C514960:fluorocholine; D002794:Choline