title: Psychotic-like symptoms and positive schizotypy are associated with mixed and ambiguous handedness in an adolescent community sample.
abstract: The objective of this study was to replicate the association between atypical handedness and psychosis-proneness in a representative sample of adolescents from the general population. It expands previous studies by (1) analyzing a variety of atypical handedness indexes (left, mixed, ambiguous, and inconsistent), (2) measuring comprehensively the multidimensionality of psychosis-proneness, and (3) analyzing the association of different patterns of atypical handedness with nonclinical dimensions of both trait (schizotypy) and sub-clinical symptom (psychotic-like experiences) levels. Seven hundred and twenty-eight adolescents were assessed for handedness by the 12-item self-report Annett Hand Preference Questionnaire and for psychosis-proneness by the Oxford-Liverpool Inventory of Feelings and Experiences and the Community Assessment of Psychic Experiences scales. Writing-hand alone did not detect associations between laterality and psychosis-proneness. Mixed- rather than left-handedness was related to psychosis-proneness, and this was more evident when analyzing subjects with ambiguous handedness exclusively. When analysis was restricted to subjects with non-ambiguous handedness, strong left-handedness was related to psychosis-proneness. The positive dimension showed a stronger association than the negative one with atypical handedness. Results partially support mixed-handedness as a marker of developmental disorders underlying both atypical lateralization and psychosis-proneness. Among various possible mixed-handedness patterns, inconsistent hand use across primary actions, and for the same action across time, seems particularly related to psychosis-proneness and thus requires further exploration.
authors: Departament de Psicologia Clínica i de Salut, Facultat de Psicologia, Universitat Autònoma de Barcelona, Bellaterra, 08193 Barcelona, Spain. neus.barrantes@uab.cat
authors: Neus
authors: N
authors: Barrantes-Vidal
authors: Lizzette
authors: L
authors: Gómez-de-Regil
authors: Blas
authors: B
authors: Navarro
authors: Jordi
authors: J
authors: Vicens-Vilanova
authors: Jordi
authors: J
authors: Obiols
authors: Thomas
authors: T
authors: Kwapil
mesh_terms: D000293:Adolescent; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008297:Male; D010551:Personality; D011618:Psychotic Disorders / Q000453:epidemiology*; D012307:Risk Factors; D012569:Schizotypal Personality Disorder / Q000453:epidemiology*; D011795:Surveys and Questionnaires