title: [Relationship between bacterial biofilm and chronic rhinosinusitis: a systematic review].
abstract: OBJECTIVE
  To evaluate the relationship between bacterial biofilm (BBF) and chronic rhinosinusitis (CRS).
  
  
  METHODS
  The database on line was searched to collect the studies on BBF and CRS. The method of meta analysis was used to analyze the data of suitable studies.
  
  
  RESULTS
  Fourteen studies were included. System evaluation indicated that the BBF detection rate in CRS group was significantly higher than that in the control group (OR = 17.01, P < 0.01), and the nasal surgery's rate of BBF positive group was significantly higher than the negative group (OR = 3.99, P < 0.01). Preoperative Lund-Kennedy endoscopic score, Lund-MacKay CT score, symptom severity score, postoperative Lund-Kennedy score after six months showed no difference between BBF positive group and negative group.
  
  
  CONCLUSIONS
  The presence of BBF is related to the pathogenesis of CRS and the history of nasal surgery.
authors: Department of Otorhinolaryngology Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
authors: Sheng-lan
authors: SL
authors: Li
authors: Shi-ming
authors: SM
authors: Chen
authors: Yu
authors: Y
authors: Xu
authors: Yong-gang
authors: YG
authors: Kong
authors: Ren-yue
authors: RY
authors: Deng
authors: Ze-zhang
authors: ZZ
authors: Tao
mesh_terms: D018407:Bacterial Physiological Phenomena; D018441:Biofilms; D002908:Chronic Disease; D006801:Humans; D059747:Nasal Surgical Procedures; D012220:Rhinitis / Q000382:microbiology*; D012852:Sinusitis / Q000382:microbiology*