title: Anterior mediastinal lymphoma arising after resection of an invasive thymoma and immunosuppressive therapy for complicated myasthenia gravis.
abstract: We present the case of a 56-year-old woman with an anterior mediastinal tumor who has past history of myasthenia gravis and invasive thymoma. Furthermore, she had superior vena cava syndrome that was caused by a rapidly growing tumor. A biopsy proved diffuse large B-cell lymphoma. After 8 courses of chemotherapy, remission of the lymphoma was achieved. Because a second primary malignancy, including lymphoma, can occur in patients with thymoma, a biopsy is necessary for tumors located in the anterior mediastinum, particularly in patients with a history of treatment for thymoma, to distinguish between recurrence and a second primary malignancy.
authors: Division of General Thoracic Surgery, Department of Surgery, School of Medicine, Keio University, Tokyo, Japan.
authors: Kohei
authors: K
authors: Hashimoto
authors: Hirohisa
authors: H
authors: Horinouchi
authors: Takashi
authors: T
authors: Ohtsuka
authors: Mitsutomo
authors: M
authors: Kohno
authors: Yotaro
authors: Y
authors: Izumi
authors: Yuichiro
authors: Y
authors: Hayashi
authors: Hiroaki
authors: H
authors: Nomori
mesh_terms: D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D008479:Mediastinal Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000188:drug therapy*; D016609:Neoplasms, Second Primary / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography; D013479:Superior Vena Cava Syndrome / Q000209:etiology; D013945:Thymoma
chemical_list: D007166:Immunosuppressive Agents