title: The use of botulinum toxin for the treatment of generalized myoclonus in a dog.
abstract: A 13 mo old spayed female mixed-breed dog presented in a nonambulatory state that was attributed to severe myoclonus secondary to distemper. The authors hypothesized that mitigating the myoclonus would help the dog become ambulatory and expedite convalescence. They injected the severely affected muscles with botulinum toxin on two separate occasions over a period of 18 days. Those injections reduced the myoclonus, helping the dog become ambulatory and attaining a comfortable, functional state.
authors: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
authors: Tom
authors: T
authors: Schubert
authors: Roger
authors: R
authors: Clemmons
authors: Sarita
authors: S
authors: Miles
authors: William
authors: W
authors: Draper
mesh_terms: D000818:Animals; D001905:Botulinum Toxins / Q000627:therapeutic use*; D004216:Distemper / Q000150:complications; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D005260:Female; D009207:Myoclonus / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D016896:Treatment Outcome
chemical_list: D001905:Botulinum Toxins