title: Controlled stacking and unstacking of peripheral chlorophyll units drives the spring-like contraction and expansion of a semi-artificial helical polymer.
abstract: Developing new strategies for controlling polymer conformations through precise molecular recognition can potentially generate a machine-like motion that is dependent on molecular information-an important process for the preparation of new intelligent nanomaterials (e.g., polymer-based nanomachines) in the field bordering between polymer chemistry and conventional supramolecular sciences. Herein, we propose a strategy to endow a helical polymer chain with dynamic spring-like (contraction/expansion) motion through the one-dimensional self-assembly (aggregation/disaggregation) of peripheral amphiphilic molecules. In this developing system, we employed a semi-artificial helical polysaccharide presenting peripheral amphiphilic chlorophyll units as a power device that undergoes contractive motion in aqueous media, driven by strong π-π interactions of its chlorophyll units or by cooperative molecular recognition of bipyridyl-type ligands through pairs of chlorophyll units, thereby converting molecular information into the regulated motion of a spring. In addition, this system also undergoes expansive motion through coordination of pyridine. We anticipate that this strategy will be applicable (when combined with the established wrapping chemistry of the helical polysaccharide) to the development of, for example, drug carriers (e.g., nano-syringes), actuators (stimuli-responsive films), and directional transporters (nano-railways), thereby extending the frontiers of supramolecular science.
authors: Department of Biomolecular Chemistry, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Shimogamo, Kyoto 606-8522, Japan. numata@kpu.ac.jp
authors: Munenori
authors: M
authors: Numata
authors: Daiki
authors: D
authors: Kinoshita
authors: Naoya
authors: N
authors: Hirose
authors: Tomohiro
authors: T
authors: Kozawa
authors: Hitoshi
authors: H
authors: Tamiaki
authors: Yoshihiro
authors: Y
authors: Kikkawa
authors: Masatoshi
authors: M
authors: Kanesato
mesh_terms: D002734:Chlorophyll / Q000737:chemistry*; D004268:DNA-Binding Proteins / Q000737:chemistry*; D008024:Ligands; D008968:Molecular Conformation; D036103:Nanotechnology; D055601:Organic Chemistry Phenomena; D011108:Polymers / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry*; D017433:Protein Structure, Secondary
chemical_list: D004268:DNA-Binding Proteins; D008024:Ligands; D011108:Polymers; D011134:Polysaccharides; D002734:Chlorophyll