title: Association between serum magnesium and risk factors of cardiovascular disease in hemodialysis patients.
abstract: BACKGROUND
  There are associations between serum magnesium level and some risk factors of cardiovascular disease and atherosclerosis, such as lipid profile, serum albumin, C-reactive protein, serum phosphorus, parathyroid hormone, and diabetes mellitus in hemodialysis patients. The aim of this study was to examine these associations.
  
  
  METHODS
  This study was conducted on 103 patients with end-stage renal disease on maintenance hemodialysis. Laboratory assessment was performed before hemodialysis session in a 12-hour fasting state. Patients were divided into two groups according to their serum magnesium concentration < 2.6 mg/dL, n = 34 and >= 2.6 mg/dL, n = 69).
  
  
  RESULTS
  The mean age of the patients was 57.4 +/- 15.4 years. The mean serum magnesium was 2.80 +/- 0.55 mg/dL (range, 1.7 mg/dL to 7 mg/dL). There were no significant differences in serum magnesium between patients with low and high values of high-density lipoprotein cholesterol, triglycerides, low-density lipoprotein cholesterol, and blood pressure. Of the 103 patients, 1 (1%) had hypomagnesemia, 41 (39.8%) had magnesium levels within normal range, and 61 (59.2%) had hypermagnesemia. Serum magnesium significantly correlated with plasma phosphorus level (r = 0.35, P < .001) and albumin (r = 0.24, P = .01). There were no correlations between serum magnesium level and age, body mass index, systolic blood pressure before dialysis, serum calcium, lipid profile, and apoprotein(a).
  
  
  CONCLUSIONS
  In our cohort of hemodialysis patients, there were no correlations between serum magnesium levels and atherogenic lipids, serum calcium, or parathyroid hormone.
authors: Nephrology Research Center, Tehran University of Medical Sciences, Tehran, Iran. khatami@hbi.ir
authors: Mohammad Reza
authors: MR
authors: Khatami
authors: Elham
authors: E
authors: Mirchi
authors: Zahra
authors: Z
authors: Khazaeipour
authors: Alireza
authors: A
authors: Abdollahi
authors: Afsaneh
authors: A
authors: Jahanmardi
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D053241:Apoprotein(a) / Q000097:blood; D001794:Blood Pressure / Q000502:physiology; D015992:Body Mass Index; D002097:C-Reactive Protein / Q000032:analysis; D002118:Calcium / Q000097:blood; D002318:Cardiovascular Diseases / Q000097:blood* / Q000150:complications; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000150:complications / Q000628:therapy; D008274:Magnesium / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood; D010758:Phosphorus / Q000097:blood; D006435:Renal Dialysis; D012307:Risk Factors; D012709:Serum Albumin / Q000032:analysis; D014280:Triglycerides / Q000097:blood; D055815:Young Adult
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D010281:Parathyroid Hormone; D012709:Serum Albumin; D014280:Triglycerides; D010758:Phosphorus; D002097:C-Reactive Protein; D053241:Apoprotein(a); D008274:Magnesium; D002118:Calcium