title: Condensin, cohesin and the control of chromatin states.
abstract: Cohesin and condensin complexes are essential for defining the topology of chromosomes through the cell cycle. Here we look at the emerging role of these complexes in regulating chromatin structure and gene expression and reflect on how these activities could be linked with chromosome topology.
authors: Cell Cycle Group, MRC Clinical Sciences Centre, Imperial College London, Du Cane Road, London W12 0NN, UK. luis.aragon@imperial.ac.uk
authors: Luis
authors: L
authors: Aragon
authors: Enrique
authors: E
authors: Martinez-Perez
authors: Matthias
authors: M
authors: Merkenschlager
mesh_terms: D000251:Adenosine Triphosphatases / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D002453:Cell Cycle; D018797:Cell Cycle Proteins / Q000235:genetics / Q000378:metabolism*; D002843:Chromatin / Q000235:genetics / Q000648:ultrastructure*; D002868:Chromosomal Proteins, Non-Histone / Q000235:genetics / Q000378:metabolism*; D022004:Chromosome Structures; D002875:Chromosomes / Q000235:genetics / Q000648:ultrastructure*; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D056890:Eukaryota / Q000166:cytology / Q000235:genetics; D005786:Gene Expression Regulation; D006801:Humans; D008938:Mitosis / Q000235:genetics; D046912:Multiprotein Complexes / Q000235:genetics / Q000378:metabolism*; D000097722:Cohesins
chemical_list: D000251:Adenosine Triphosphatases; D018797:Cell Cycle Proteins; D002843:Chromatin; D002868:Chromosomal Proteins, Non-Histone; D004268:DNA-Binding Proteins; D046912:Multiprotein Complexes; D000097722:Cohesins; C108312:condensin complexes