title: Drug-induced linear IgA bullous dermatosis after discontinuation of cefuroxime axetil treatment.
abstract: BACKGROUND
  Linear immunoglobulin A (IgA) bullous dermatosis (LABD) is a rare autoimmune blistering disorder. The disease may be either idiopathic or druginduced. Over the past 30 years, approximately one hundred LABD cases have been described as induced by a wide range of drugs, chiefly antibiotics.
  
  
  METHODS
  We report the case of 37-year-old woman who developed pruritic bullous lesions spread all over the body three weeks after her last dose of cefuroxime axetil. Antibiotic therapy was started due to rhino-sinusitis.
  
  
  CONCLUSIONS
  In most reported cases of drug-induced LABD, skin lesions occur within the time of drug administration. However, the onset of disease may be even after discontinuation of treatment. It seems that in such cases, other clinical conditions (like infection) act, as cofactors of immunologic response.
authors: Jagiellonian University School of Medicine, Department of Dermatology, Cracow, Poland.
authors: Maciej
authors: M
authors: Pastuszczak
authors: Sylwia
authors: S
authors: Lipko-Godlewska
authors: Andrzej K
authors: AK
authors: Jaworek
authors: Anna
authors: A
authors: Wojas-Pelc
keywords: IgA dermatosis; LABD; cefuroxime axetil; drug-induced