title: Silver nanoparticles decrease body weight and locomotor activity in adult male rats.
abstract: Silver nanoparticles (Ag-NPs) are widely used in FDA regulated products. The physical-chemical properties of Ag-NPs are characterized using various instruments. The dose-dependent activity and body weight alterations are evaluated after rats were exposed to Ag nanoparticles, suggesting a major human health risk, given the wide application of silver nanomaterials.
authors: Nanotechnology Core Facility, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079, USA. yongbin.zhang@fda.hhs.gov
authors: Yongbin
authors: Y
authors: Zhang
authors: Sherry A
authors: SA
authors: Ferguson
authors: Fumiya
authors: F
authors: Watanabe
authors: Yvonne
authors: Y
authors: Jones
authors: Yang
authors: Y
authors: Xu
authors: Alexandru S
authors: AS
authors: Biris
authors: Saber
authors: S
authors: Hussain
authors: Syed F
authors: SF
authors: Ali
mesh_terms: D000818:Animals; D001835:Body Weight / Q000187:drug effects*; D008297:Male; D053768:Metal Nanoparticles; D017348:Microscopy, Electron, Scanning Transmission; D046529:Microscopy, Electron, Transmission; D009043:Motor Activity / Q000187:drug effects*; D051381:Rats; D012834:Silver / Q000737:chemistry*
chemical_list: D012834:Silver