title: Total synthesis of paracaseolide A.
abstract: The total synthesis of paracaseolide A, a valuable cell-cycle progression inhibitor, was accomplished in 8 steps from known compounds, with 6.6% overall yield. The synthetic strategy creates strong potential for diversification.
authors: Department of Chemistry, Iowa State University, Ames, Iowa 50011, USA.
authors: Tezcan
authors: T
authors: Guney
authors: George A
authors: GA
authors: Kraus
mesh_terms: D015107:4-Butyrolactone / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D002453:Cell Cycle / Q000187:drug effects; D015394:Molecular Structure; D043982:Rhizophoraceae / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: C569208:paracaseolide A; D015107:4-Butyrolactone