title: Embryonal tumor with abundant neuropil and true rosettes: a systematic literature review and report of 2 new cases.
abstract: Embryonal tumor with abundant neuropil and true rosettes has been recently defined as a distinct central nervous system embryonal neoplasm, although it was initially regarded as a subtype of central nervous system primitive neuroectodermal tumor. To date 70 cases have been reported. We have performed a literature review and we present 2 new cases. Analysis of the reported data revealed that radiotherapy, tumor excision and high-dose adjuvant chemotherapy with sequential autologous hematopoietic stem cell rescue have a prognostic significance.
authors: 1Department of Neurosurgery, Children's Hospital "Agia Sofia," Athens, Greece.
authors: George A
authors: GA
authors: Alexiou
authors: Kalliopi
authors: K
authors: Stefanaki
authors: George
authors: G
authors: Vartholomatos
authors: George
authors: G
authors: Sfakianos
authors: Neofytos
authors: N
authors: Prodromou
authors: Maria
authors: M
authors: Moschovi
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007223:Infant; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis* / Q000628:therapy; D019581:Neuropil / Q000473:pathology*
keywords: brain tumor; embryonal tumor with abundant neuropil and true rosettes