title: Use of sophisticated intra-operative monitoring in resuscitation of unexpected cardiovascular collapse during general anaesthesia.
abstract: BACKGROUND
  The diagnosis of intraoperative anaphylaxis is important but can be difficult as the symptoms can be varying and dependent on patient factors.
  
  
  METHODS
  We describe an acute, unexpected and life threatening cardiovascular (CV) collapse, presumed to be due to an acute anaphylactic reaction secondary to gelatin administration, following induction of general anaesthesia (GA), in an ASA 3 patient scheduled for axillo-bifemoral bypass.
  
  
  CONCLUSIONS
  The management of the profound cardiovascular (CV) collapse was greatly assisted by sophisticated haemodynamic, depth of anaesthesia and cerebral oximetry monitoring.(1) As far as we are aware this is the first such case where the full haemodynamic, depth of anaesthesia and cerebral oxygenation changes during CV collapse, presumed due to an acute anaphylactic reaction under GA have been fully documented.
  
  
  CONCLUSIONS
  The use of advanced monitoring intraoperatively proved extremely useful in guiding the resuscitation of a life threatening allergic reaction under general anaesthesia.
authors: Department of Anaesthetics, King's College Hospital NHS Foundation Trust,Denmark Hill, London SE5 9RS, United Kingdom. Electronic address: audreytan@me.com.
authors: A
authors: A
authors: Tan
authors: B
authors: B
authors: Shephard
authors: D
authors: D
authors: Green