title: High prevalence of antibiotic resistance and molecular characterization of integrons among Shigella isolates in Eastern China.
abstract: A total of 747 Shigella isolates were collected from hospitals in Jiangsu Province of China. Susceptibilities to antimicrobials and integrons were tested. A total of 78.3% of S. flexneri isolates and a total of 74.3% S. sonei isolates were resistant to at least three antibiotics. Of the Shigella isolates, 74.7% had integron I and 82.6% had integron II. The conjunction of the high prevalence of integrons in Shigella and high resistance to antimicrobials will lead to rapid dissemination of resistant genes in this region.
authors: Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, China.
authors: Yun
authors: Y
authors: Shen
authors: Huimin
authors: H
authors: Qian
authors: Junjun
authors: J
authors: Gong
authors: Feifei
authors: F
authors: Deng
authors: Chen
authors: C
authors: Dong
authors: Lu
authors: L
authors: Zhou
authors: Hongxiong
authors: H
authors: Guo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004269:DNA, Bacterial / Q000235:genetics* / Q000302:isolation & purification; D024901:Drug Resistance, Multiple, Bacterial / Q000187:drug effects / Q000235:genetics*; D004405:Dysentery, Bacillary / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission*; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D032023:Integrons / Q000235:genetics*; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015995:Prevalence; D012763:Shigella flexneri / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D012764:Shigella sonnei / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial