title: Automatic detection of optic disc based on PCA and mathematical morphology.
abstract: The algorithm proposed in this paper allows to automatically segment the optic disc from a fundus image. The goal is to facilitate the early detection of certain pathologies and to fully automate the process so as to avoid specialist intervention. The method proposed for the extraction of the optic disc contour is mainly based on mathematical morphology along with principal component analysis (PCA). It makes use of different operations such as generalized distance function (GDF), a variant of the watershed transformation, the stochastic watershed, and geodesic transformations. The input of the segmentation method is obtained through PCA. The purpose of using PCA is to achieve the grey-scale image that better represents the original RGB image. The implemented algorithm has been validated on five public databases obtaining promising results. The average values obtained (a Jaccard's and Dice's coefficients of 0.8200 and 0.8932, respectively, an accuracy of 0.9947, and a true positive and false positive fractions of 0.9275 and 0.0036) demonstrate that this method is a robust tool for the automatic segmentation of the optic disc. Moreover, it is fairly reliable since it works properly on databases with a large degree of variability and improves the results of other state-of-the-art methods.
authors: Instituto Interuniversitario de Investigación en Bioingeniería y Tecnología Orientada al Ser Humano, Universitat Politècnica de València, 46022 Valencia, Spain. smorales@labhuman.i3bh.es
authors: Sandra
authors: S
authors: Morales
authors: Valery
authors: V
authors: Naranjo
authors: Us
authors: U
authors: Angulo
authors: Mariano
authors: M
authors: Alcaniz
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D005260:Female; D005654:Fundus Oculi; D005901:Glaucoma / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000473:pathology; D009898:Optic Disk / Q000033:anatomy & histology*; D025341:Principal Component Analysis / Q000379:methods*; D015203:Reproducibility of Results