title: A review of the potential therapeutic role of statins in the treatment of Alzheimer's disease: current research and opinion.
abstract: Alzheimer's disease is one of the most prevalent neurodegenerative disorders. However, there is no current treatment, which definitively influences disease progression over a sustained period. Numerous studies linking an increase in serum cholesterol, mainly during midlife, with the pathogenic process of Alzheimer's disease have been published. Therefore, the role of statins as a therapy in this disorder may be of great interest. The aim of the present review is to summarize of the role of statins in the treatment of Alzheimer's disease.
authors: Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain ; Department of Medicine, Complutense University, Madrid, Spain ; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Madrid, Spain ; Instituto de Salud Carlos III, Madrid, Spain.
authors: Alvaro
authors: A
authors: Sánchez-Ferro
authors: Julián
authors: J
authors: Benito-León
authors: Alex J
authors: AJ
authors: Mitchell
authors: Félix
authors: F
authors: Bermejo-Pareja
keywords: HMGCoA-inhibitors; animal models; clinical trials; cognitive function; epidemiology; prevention