title: Peripheral artery disease in korean patients undergoing percutaneous coronary intervention: prevalence and association with coronary artery disease severity.
abstract: Peripheral artery disease (PAD) is an important marker for the risk stratification of patients with coronary artery disease (CAD). We investigated the prevalence of PAD in patients undergoing percutaneous coronary intervention (PCI) with CAD and the relationship between ankle-brachial pressure index (ABPI) and CAD severity. A total of 711 patients undergoing PCI for CAD from August 2009 to August 2011 were enrolled. PAD diagnosis was made using the ABPI. The prevalence of PAD was 12.8%. In PAD patients, mean values of right and left ABPI were 0.71 ± 0.15 and 0.73 ± 0.15. Patients with PAD had a higher prevalence of left main coronary disease (14.3% vs 5.8%, P = 0.003), more frequently had multivessel lesions (74.9% vs 52.1%, P < 0.001) and had higher SYNTAX score (18.2 ± 12.3 vs 13.1 ± 8.26, P = 0.002). Using multivariate analysis, we determined that left main CAD (OR, 2.954; 95% CI, 1.418-6.152, P = 0.004) and multivessel CAD (OR, 2.321; 95% CI, 1.363-3.953, P = 0.002) were both independently associated with PAD. We recommend that ABPI-based PAD screening should be implemented in all patients undergoing PCI with CAD, especially in severe cases.
authors: Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors: Eun Kyoung
authors: EK
authors: Kim
authors: Pil Sang
authors: PS
authors: Song
authors: Jeong Hoon
authors: JH
authors: Yang
authors: Young Bin
authors: YB
authors: Song
authors: Joo-Yong
authors: JY
authors: Hahn
authors: Jin-Ho
authors: JH
authors: Choi
authors: Hyeon-Cheol
authors: HC
authors: Gwon
authors: Sang Hoon
authors: SH
authors: Lee
authors: Kyung Pyo
authors: KP
authors: Hong
authors: Jeong Euy
authors: JE
authors: Park
authors: Duk-kyung
authors: DK
authors: Kim
authors: Seung-Hyuk
authors: SH
authors: Choi
mesh_terms: D000368:Aged; D055109:Ankle Brachial Index; D044466:Asian People; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D062645:Percutaneous Coronary Intervention; D058729:Peripheral Arterial Disease / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D012720:Severity of Illness Index
keywords: Atherosclerosis; Coronary Artery Disease; Peripheral Artery Disease