title: Photoprotective activity of resveratrol analogues.
abstract: Resveratrol is a promising agent for protecting human skin from UV radiation and to reduce the occurrence of cutaneous malignancies. We describe the photoprotective activity of six resveratrol analogues using the diffuse transmittance technique to determine the SPF and the protection against UVA radiation. The analogues presented a varied profile of photoprotection, the SPF ranging from 2 to 10 and the UVAPF from 0 to 9. Among the six compounds tested, the protection against UVB sunrays provided by compound B was more significant than the protection provided by resveratrol; compounds C, D, E and F show photoprotection similar to resveratrol.
authors: Núcleo de Pesquisa e Inovação em Ciências da saúde (NUPICS), Universidade Federal de Juiz de Fora, Campus Universitário, Juiz de Fora 36036-900, Brazil.
authors: Hudson Caetano
authors: HC
authors: Polonini
authors: Larissa Lavorato
authors: LL
authors: Lima
authors: Karla Mara
authors: KM
authors: Gonçalves
authors: Antônio Márcio Resende
authors: AM
authors: do Carmo
authors: Adilson David
authors: AD
authors: da Silva
authors: Nádia Rezende Barbosa
authors: NR
authors: Raposo
mesh_terms: D006801:Humans; D000077185:Resveratrol; D012867:Skin / Q000187:drug effects / Q000528:radiation effects; D013267:Stilbenes / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship; D059405:Sun Protection Factor; D013473:Sunscreening Agents / Q000737:chemistry* / Q000494:pharmacology; D014466:Ultraviolet Rays
chemical_list: D013267:Stilbenes; D013473:Sunscreening Agents; D000077185:Resveratrol