title: Hemophagocytic lymphohistiocytosis associated with visceral leishmaniasis in late adulthood.
abstract: We describe a case of hemophagocytic lymphohistiocytosis related to visceral leishmaniasis in late adulthood. Because clinical features of visceral leishmaniasis can mimic those of hemophagocytic lymphohistiocytosis, diagnosing leishmaniasis as the underlying etiology can be quite challenging. In our case, treatment with amphotericin B resulted in a dramatic resolution of clinical abnormalities.
authors: Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. guilhermegrossi@terra.com.br
authors: Guilherme Grossi Lopes
authors: GG
authors: Cançado
authors: Guilherme Gomes
authors: GG
authors: Freitas
authors: Flavia Helena Fidelis
authors: FH
authors: Faria
authors: Antonio Vaz
authors: AV
authors: de Macedo
authors: Vandack
authors: V
authors: Nobre
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D004211:Disseminated Intravascular Coagulation / Q000150:complications / Q000473:pathology; D006529:Hepatomegaly / Q000209:etiology / Q000473:pathology; D006801:Humans; D007898:Leishmaniasis, Visceral / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000473:pathology; D008297:Male; D013163:Splenomegaly / Q000209:etiology / Q000473:pathology
chemical_list: D000893:Anti-Inflammatory Agents; D000981:Antiprotozoal Agents; D003907:Dexamethasone; D000666:Amphotericin B