title: Novel techniques and innovation in blood purification: a clinical update from Kidney Disease: Improving Global Outcomes.
abstract: Mortality in patients with end-stage renal disease (ESRD) remains unacceptably high. Emerging techniques and advances in dialysis technology have the potential to improve clinical outcomes in the ESRD population. This report summarizes the deliberations and recommendations of a conference sponsored by Kidney Disease: Improving Global Outcomes to address the following questions: (1) what is the appropriate frequency and duration of hemodialysis; (2) how should we optimize water quality and dialysate composition; and (3) what technical innovations in blood purification and bioengineering can result in better clinical outcomes? The conference report will augment our current understanding of clinical practice in blood purification and will pose several high-priority research questions.
authors: University Health Network, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada. christopher.chan@uhn.on.ca
authors: Christopher T
authors: CT
authors: Chan
authors: Adrian
authors: A
authors: Covic
authors: Jonathan C
authors: JC
authors: Craig
authors: Andrew
authors: A
authors: Davenport
authors: Bertram L
authors: BL
authors: Kasiske
authors: Martin K
authors: MK
authors: Kuhlmann
authors: Nathan W
authors: NW
authors: Levin
authors: Philip K T
authors: PK
authors: Li
authors: Francesco
authors: F
authors: Locatelli
authors: Michael V
authors: MV
authors: Rocco
authors: David C
authors: DC
authors: Wheeler
mesh_terms: D002021:Buffers; D015314:Dialysis Solutions / Q000032:analysis; D005240:Feasibility Studies; D017583:Hemodiafiltration; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D006435:Renal Dialysis / Q000379:methods*; D009626:Terminology as Topic; D062666:Vascular Access Devices; D014867:Water / Q000592:standards
chemical_list: D002021:Buffers; D015314:Dialysis Solutions; D014867:Water