title: Optimizing working-space in laparoscopy: measuring the effect of mechanical bowel preparation in a porcine model.
abstract: BACKGROUND
  Adequate working space is a prerequisite for safe and efficient minimal access surgery. No objective data exist in literature about the effect of mechanical bowel preparation (MBP) on working space in laparoscopic surgery. We objectively measured this effect with computed tomography in a porcine laparoscopy model.
  
  
  METHODS
  Using standardized anesthesia, twelve 20-kg pigs without MBP and eight 20-kg pigs with MBP were studied with computed tomography at intra-abdominal pressure (IAP) levels of 0, 5, 10, and 15 mmHg. Volumes and dimensions of the pneumoperitoneum were measured on reconstructed CT images and compared between the pigs with and those without MBP.
  
  
  RESULTS
  A reproducible and statistically significant increase of approximately 500 ml in pneumoperitoneum volume was found in the MBP group at all levels of IAP. This represents a 43 % relative increase at a pneumoperitoneum pressure of 5 mmHg, 21 % at IAP 10 mmHg, and 18 % at IAP 15 mmHg. Peak inspiratory pressure was lower at IAP 0 and 5 mmHg in the MBP group. Anteroposterior diameter in the group with MBP was lower at 0 mmHg, but abdominal dimensions were similar in both groups at all other IAPs. This shows that the gain in working space is due to a diminished volume of the intra-abdominal content and not to compression or displacement of the bowel.
  
  
  CONCLUSIONS
  MBP increases working space by reducing bowel content. Especially at low intra-abdominal working pressures, the increase in working space associated with MBP could represent an important benefit in challenging laparoscopic surgery.
authors: Department of Pediatric Surgery, Erasmus MC: University Medical Center Rotterdam, P.O. Box 2060, 3000 CB, Rotterdam, The Netherlands. john.vlot@erasmusmc.nl
authors: John
authors: J
authors: Vlot
authors: Juliette C
authors: JC
authors: Slieker
authors: René
authors: R
authors: Wijnen
authors: Johan F
authors: JF
authors: Lange
authors: Klaas N M A
authors: KN
authors: Bax
mesh_terms: D000005:Abdomen / Q000033:anatomy & histology*; D000818:Animals; D005260:Female; D010535:Laparoscopy / Q000379:methods*; D011028:Pneumoperitoneum, Artificial / Q000379:methods*; D011860:Radiography, Abdominal; D034421:Sus scrofa; D014057:Tomography, X-Ray Computed