title: [Post-Intensive Care Unit mortality and related prognostic factors in a cohort of critically ill patients with multi-organ dysfunction].
abstract: OBJECTIVE
  To assess the post-Intensive Care Unit (ICU) mortality (in-hospital and one year after hospital discharge) and the associated factors.
  
  
  METHODS
  Cohort design in medical-surgical patients with multi-organ dysfunction syndrome (MODS) during the first 24h of admission to ICU. We recorded the following data: personal background, functional general situation, general information about admission to ICU, hospital stay and contact by phone after one year of hospital discharge. We registered mortality at the follow-up at anytime. Cox regression was performed to evaluate mortality factors.
  
  
  RESULTS
  Five hundred and forty five patients were recruited. During the study period 256 patients (52.9%) died; out of them 29.5% in ICU; 14.8% of 384 patients transferred to the ward died. Of 327 discharged patients, 266 (81.3%) were contacted; 14.3% of those had died. In-hospital death-related factors were age (odds ratio [OR] 1.04; 95% confidence interval [95% CI] 1.02-1.06; P<.01) and a decreased functional general status (OR 1.7; 95% CI 1.1-2.9; P<.05). Post-hospitalisation mortality-related variables were: diminished functional general status (OR 2.42; 95% CI 1.23-4.75; P<.01) and readmission after discharge from hospital (1.45 OR; 95% CI 1.19-1.76; P<.001).
  
  
  CONCLUSIONS
  Patients admitted for a medical-surgical MODS presented a mortality of 52.9% within one year. The factors influencing hospital mortality are age and a generally diminished functional status, both being not modifiable factors. After discharge, the decreased general functional status remained central along with the re-hospitalisation.
authors: Servicio de Medicina Intensiva, Complejo Hospitalario de Toledo, Toledo, España.
authors: Victoria A
authors: VA
authors: Hortigüela-Martín
authors: Marcelino
authors: M
authors: Sanchez-Casado
authors: Sancho
authors: S
authors: Rodríguez-Villar
authors: Manuel
authors: M
authors: Quintana-Díaz
authors: Carlos
authors: C
authors: Marco-Schulke
authors: Vicente
authors: V
authors: Gómez-Tello
authors: Henar
authors: H
authors: Cabezas Martín
authors: Maria Ángeles
authors: MÁ
authors: Arrese-Cosculluela
mesh_terms: D000359:Aftercare; D000368:Aged; D016638:Critical Illness / Q000401:mortality*; D003953:Diagnosis-Related Groups; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D007362:Intensive Care Units; D053208:Kaplan-Meier Estimate; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000401:mortality*; D010351:Patient Discharge; D010360:Patient Transfer; D016016:Proportional Hazards Models; D012720:Severity of Illness Index; D013030:Spain / Q000453:epidemiology; D062606:Tertiary Care Centers / Q000706:statistics & numerical data