title: [Changes of photoreceptor layer on spectral domain optical coherence tomography in idiopathic macular hole after vitreous surgery combined with air tamponade].
abstract: OBJECTIVE
  To evaluate the tamponade effect of sterilized air in vitrectomy for idiopathic macular hole (IMH) as well as changes of photoreceptor layer after surgery.
  
  
  METHODS
  Forty-five eyes of 45 consecutive cases underwent vitrectomy and air tamponade. Surgical outcomes were retrospectively analyzed, consisting of logarithm of the minimal angle of resolution (logMAR) and SD-OCT findings including the size of IMH and the photoreceptor layer defect.
  
  
  RESULTS
  Preoperatively, mean BCVA was 0.08 (range, 0.4 to HM), mean hole diameter was 827.4 µm (range, 204 to 1616 µm), and mean diameter of photoreceptor layer defect was 1988.9 µm (range, 792 to 3444 µm). The primary closure rate was 75.6%. One month after surgery, mean BCVA was 0.13 (range, 0.5 to LP), and mean diameter of photoreceptor layer defect was 1285.1 µm (range, 166 to 2553 µm), both presenting a significant decrease. Preoperative hole diameter and postoperative diameter of photoreceptor layer defect were statistically significantly correlated with postoperative BCVA (r = 0.526, 0.628; P < 0.05).
  
  
  CONCLUSIONS
  Vitrectomy plus air tamponade is safe and effective for the treatment of IMH, and the time for face-down positioning is obviously shortened. Preoperative hole diameter and postoperative diameter of photoreceptor layer defect are major predictive factors of visual acuity.
authors: Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
authors: Feng
authors: F
authors: He
authors: Wei-hong
authors: WH
authors: Yu
authors: Lin
authors: L
authors: Zheng
authors: Fang-tian
authors: FT
authors: Dong
mesh_terms: D000328:Adult; D000368:Aged; D000388:Air; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010786:Photoreceptor Cells / Q000000981:diagnostic imaging*; D011859:Radiography; D012167:Retinal Perforations / Q000000981:diagnostic imaging* / Q000601:surgery / Q000628:therapy*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014821:Vitrectomy