title: Evaluation of 'east-to-west' ether-forming strategies for the total synthesis of maoecrystal V.
abstract: Model systems that evaluated different approaches to construct the central ether ring of maoecrystal V are described. Our first model systems attempted the ether formation using C-H functionalization reactions, which led to interesting rearrangements but none of the desired ether product. An intramolecular conjugate addition strategy was then explored that successfully formed the targeted C-O bond but resulted in the undesired stereochemistry.
authors: Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208.
authors: Kiel E
authors: KE
authors: Lazarski
authors: Berkcan
authors: B
authors: Akpinar
authors: Regan J
authors: RJ
authors: Thomson