title: Squamous cell carcinoma with rhabdoid phenotype of skin/soft tissue in a transplant patient: an exceptional case and review of the literature.
abstract: Squamous cell carcinoma with rhabdoid features (SCCRF) is a very rare and unusual cutaneous tumor. Here, we report an extraordinary case diagnosed by fine needle aspiration biopsy, in a 66-year-old man, status post multiple organ transplantation. The patient presented with a large ulcerating fungating mass in his forearm that had all the light microscopic and immunohistochemical features of a SCCRF. Previously six cases of SCCRF phenotype diagnosed by surgical pathology have been reported. This is the first case diagnosed cytologically. A review of the literature with emphasis on the differential diagnoses of such unusual rhabdoid-like tumors in fine-needle aspiration biopsy and the potential molecular mechanism for rhabdoid phenotype in transplant patients are discussed.
authors: Department of Pathology and Cell Biology, University of South Florida, Tampa, Florida, USA.
authors: Pushpa
authors: P
authors: Allam-Nandyala
authors: Marilyn M
authors: MM
authors: Bui
authors: Ronald
authors: R
authors: DeConti
authors: Chetna
authors: C
authors: Purohit
authors: Soner
authors: S
authors: Altiok
mesh_terms: D000368:Aged; D044963:Biopsy, Fine-Needle; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology*; D002467:Cell Nucleus / Q000473:pathology; D005542:Forearm; D006801:Humans; D008297:Male; D016377:Organ Transplantation; D010641:Phenotype; D018335:Rhabdoid Tumor / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000473:pathology*