title: Child health update: estrogen cream for labial adhesion in girls.
abstract: OBJECTIVE
  Should I prescribe estrogen cream to treat labial adhesion in my prepubertal female patients?
  
  
  CONCLUSIONS
  Many physicians offer young girls estrogen cream to be applied on the labia for several weeks to treat labial adhesion. While no randomized controlled trial data are available, the success rate of such creams is reported in the literature to be close to 90%. Side effects of estrogen cream are mild and transient. Although the ideal frequency and length of treatment with estrogen cream has yet to be determined, most treatment recommendations suggest application of the cream 1 to 2 times a day; treatment should be applied for a few weeks before considering surgical alternatives.
authors: BC Children's Hospital, Department of Pediatrics, Room K4-226, Ambulatory Care Bldg, 4480 Oak St, Vancouver, BC V6H 3V4. rgoldman@cw.bc.ca
authors: Ran D
authors: RD
authors: Goldman
mesh_terms: D000279:Administration, Cutaneous; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D001623:Betamethasone / Q000627:therapeutic use*; D002675:Child, Preschool; D004967:Estrogens / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007223:Infant; D000267:Tissue Adhesions / Q000188:drug therapy; D014845:Vulvar Diseases / Q000188:drug therapy*
chemical_list: D000893:Anti-Inflammatory Agents; D004967:Estrogens; D001623:Betamethasone