title: Candida parapsilosis meningitis in a patient with AIDS. Report of a case and review of the literature.
abstract: BACKGROUND
  Candida parapsilosis is an important species in the genus Candida that plays a significant role in hospitalized patients with nosocomial infections. In patients with HIV infection or AIDS, central nervous system involvement by Candida species is exceptional.
  
  
  METHODS
  Here we report a case of an acute meningoencephalitis due to C. parapsilosis in an adult patient with AIDS. We describe the clinical manifestations, the diagnosis methods, antifungal therapy and outcome.
  
  
  CONCLUSIONS
  C. parapsilosis is uncommonly reported as a cause of meningitis in AIDS patients. A higher index of suspicion and culture is necessary to confirm the diagnosis of candidal meningoencephalitis.
authors: HIV/AIDS Division, F. J. Muñiz Infectious Diseases Hospital, Buenos Aires, Argentina. marcelocorti@fibertel.com.ar
authors: Marcelo
authors: M
authors: Corti
authors: Rubén
authors: R
authors: Solari
authors: Luis
authors: L
authors: De Carolis
authors: Diana
authors: D
authors: Cangelosi
authors: Alicia
authors: A
authors: Arechavala
authors: Ricardo
authors: R
authors: Negroni
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D000208:Acute Disease; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002175:Candida / Q000145:classification / Q000254:growth & development / Q000302:isolation & purification*; D058365:Candidiasis, Invasive / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D002555:Cerebrospinal Fluid / Q000382:microbiology; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D008297:Male; D016921:Meningitis, Fungal / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D010352:Patient Dropouts
chemical_list: D019380:Anti-HIV Agents; D000935:Antifungal Agents; D015725:Fluconazole