title: Evaluation of portable blood glucose meters for measurement of blood glucose concentration in ferrets (Mustela putorius furo).
abstract: OBJECTIVE
  To evaluate agreement of 3 models of portable blood glucose meters (PBGMs; 2 designed for use with human samples and 1 designed for veterinary use) with a laboratory analyzer for measurement of blood glucose concentrations in ferrets (Mustela putorius furo).
  
  
  METHODS
  Evaluation study.
  
  
  METHODS
  52 ferrets.
  
  
  METHODS
  Samples were analyzed with 4 PBGMs (whole blood) and a laboratory analyzer (plasma). Two PBGMs of the model designed for veterinary use were tested; each was set to a code corresponding to canine or feline sample analysis throughout the study. Agreement and bias between measurements obtained with the PBGMs and the laboratory analyzer were assessed with Bland-Altman plots. Linear regression analysis was performed to evaluate associations with venipuncture site by comparison of central (jugular) and peripheral (lateral saphenous or cephalic) venous blood samples.
  
  
  RESULTS
  Plasma glucose concentrations measured with the laboratory analyzer ranged from 41 to 160 mg/dL. Results from the PBGM for veterinary use coded to test a canine blood sample had the greatest agreement with the laboratory analyzer (mean bias, 1.9 mg/dL); all other PBGMs significantly underestimated blood glucose concentrations. A PBGM designed for use with human samples had the least agreement with the laboratory analyzer (mean bias, -34.0 mg/dL). Blood glucose concentration was not significantly different between central and peripheral venous blood samples for any analyzer used.
  
  
  CONCLUSIONS
  Significant underestimation of blood glucose concentrations as detected for 3 of the 4 PBGMs used in the study could have a substantial impact on clinical decision making. Verification of blood glucose concentrations in ferrets with a laboratory analyzer is highly recommended.
authors: Gulf Coast Avian & Exotics, Gulf Coast Veterinary Specialists, 1111 W Loop S, Ste 110, Houston, TX 77027, USA.
authors: Olivia A
authors: OA
authors: Petritz
authors: Natalie
authors: N
authors: Antinoff
authors: Sue
authors: S
authors: Chen
authors: Philip H
authors: PH
authors: Kass
authors: Joanne R
authors: JR
authors: Paul-Murphy
mesh_terms: D000818:Animals; D001774:Blood Chemical Analysis / Q000295:instrumentation / Q000662:veterinary*; D001786:Blood Glucose / Q000032:analysis*; D005289:Ferrets / Q000097:blood*; D019095:Point-of-Care Systems
chemical_list: D001786:Blood Glucose