title: Macrocyclic glycohybrid toolbox identifies novel antiangiogenesis agents from zebrafish assay.
abstract: A practical and modular approach to obtain a diverse set of 14-membered macrocyclic compounds from carbohydrates is developed that utilizes functional groups at C-1 and C-5. The evaluation of this toolbox in various zebrafish assays led to the identification of 2.7f as an antiangiogenesis agent.
authors: Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India.
authors: Bhanudas
authors: B
authors: Dasari
authors: Srinivas
authors: S
authors: Jogula
authors: Ramdas
authors: R
authors: Borhade
authors: Sridhar
authors: S
authors: Balasubramanian
authors: Gayathri
authors: G
authors: Chandrasekar
authors: Satish Srinivas
authors: SS
authors: Kitambi
authors: Prabhat
authors: P
authors: Arya
mesh_terms: D020533:Angiogenesis Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D002241:Carbohydrates / Q000737:chemistry*; D015195:Drug Design; D047028:Macrocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D015027:Zebrafish
chemical_list: D020533:Angiogenesis Inhibitors; D002241:Carbohydrates; D047028:Macrocyclic Compounds