title: Innate affairs of allergens.
abstract: Activation of receptors of the innate immune system is a critical step in the initiation of immune responses. It has been shown that dominant allergens have properties that could allow them to interact with toll-like and C-type lectin receptors to favour Th2-biased responses and many bind lipids and glycans that could associate with ligands to mimic pathogen-associated microbial patterns. In accord with the proposed allergen-specific innate interactions it has been shown that the immune responses to different allergens and antigens from the same source are not necessarily coordinately regulated.
authors: Centre for Child Health Research, University of Western Australia, Telethon Institute for Child Health Research, Subiaco, Western Australia, Australia. wayne@ichr.uwa.edu.au
authors: W R
authors: WR
authors: Thomas
mesh_terms: D000485:Allergens / Q000276:immunology* / Q000378:metabolism; D057056:Cysteine Proteases / Q000378:metabolism; D006801:Humans; D007113:Immunity, Innate; D037181:Lectins, C-Type / Q000378:metabolism; D018716:Molecular Mimicry / Q000276:immunology; D011485:Protein Binding; D051192:Receptors, Pattern Recognition / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D000485:Allergens; D037181:Lectins, C-Type; D051192:Receptors, Pattern Recognition; D057056:Cysteine Proteases