title: Multidrug resistance gene cfr in methicillin-resistant coagulase-negative staphylococci from chickens, ducks, and pigs in China.
abstract: The multidrug-resistance gene cfr was detected in coagulase-negative staphylococci from 3/401 pigs, 15/305 chickens, and 3/78 ducks from 31 different farms and one slaughterhouse in 2 provinces of China. Twenty of the 21 cfr-positive isolates were methicillin-resistant. Various SmaI-PFGE patterns were observed among the isolates of the same staphylococcal species and suggested horizontal transfer of cfr rather than clonal expansion. The detection of cfr on plasmids in the majority of the isolates supported this assumption. Analysis of the drug usage records of the farms strongly correlated with the resistance patterns of the cfr-positive isolates and suggested that antimicrobial use on farms supports the spread of the cfr gene.
authors: Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, PR China.
authors: Yang
authors: Y
authors: Wang
authors: Tao
authors: T
authors: He
authors: Stefan
authors: S
authors: Schwarz
authors: Qin
authors: Q
authors: Zhao
authors: Zhangqi
authors: Z
authors: Shen
authors: Congming
authors: C
authors: Wu
authors: Jianzhong
authors: J
authors: Shen
mesh_terms: D000003:Abattoirs; D000818:Animals; D000829:Animals, Domestic / Q000382:microbiology*; D002645:Chickens; D002681:China; D024901:Drug Resistance, Multiple, Bacterial; D004372:Ducks; D016521:Electrophoresis, Gel, Pulsed-Field; D022761:Gene Transfer, Horizontal; D058889:Molecular Typing; D010957:Plasmids; D013203:Staphylococcal Infections / Q000382:microbiology / Q000662:veterinary*; D013210:Staphylococcus / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D013552:Swine