title: Impact of intensive high-fat ingestion in the early stage of recovery from exercise training on substrate metabolism during exercise in humans.
abstract: Not only increasing body carbohydrate (CHO) stores before exercise but also suppressing CHO oxidation during exercise is important for improving endurance performance. We tested the hypothesis that intensive high-fat ingestion in the early stage of recovery from exercise training (ET) for 2 d would suppress CHO oxidation during exercise by increasing whole body lipolysis and/or fat oxidation. In a randomized crossover design, on days 1 and 2, six male subjects performed cycle ET at 50% peak oxygen consumption (VO(2 peak)) for 60-90 min, and consumed a control diet (CON: 1,224 kcal, 55% carbohydrate, 30% fat) or the same diet supplemented with high fat (HF: 1,974 kcal, 34% carbohydrate, 56% fat) 1 h after ET, with the diet other than post-ET similar in both trials. On day 3, subjects performed cycle exercise at 65% VO(2 peak) until exhaustion. Exercise time to exhaustion was longer in the HF trial than in the CON trial (CON: 48.9 ± 6.7 vs. HF: 55.8 ± 7.7 min, p<0.05). In the HF trial, total fat oxidation until exhaustion was higher, accompanied by higher post-exercise plasma glycerol concentration, than in the CON trial (CON: 213 ± 54 vs. HF: 286 ± 63 kcal, p<0.05), whereas total carbohydrate oxidation until exhaustion was not different between trials. These results suggest that intensive high-fat ingestion in the early stage of recovery from ET for a few days until the day before exercise was an effective means of eliciting a CHO-sparing effect during exercise by enhancing fat metabolism.
authors: Faculty of Human Sciences, Waseda University, Tokorozawa, Japan. icchi@fuji.waseda.jp
authors: Takashi
authors: T
authors: Ichinose
authors: Natsuko
authors: N
authors: Arai
authors: Tomoaki
authors: T
authors: Nagasaka
authors: Masaya
authors: M
authors: Asano
authors: Kenji
authors: K
authors: Hashimoto
mesh_terms: D001786:Blood Glucose / Q000032:analysis; D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D050260:Carbohydrate Metabolism; D018592:Cross-Over Studies; D004032:Diet; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004041:Dietary Fats / Q000008:administration & dosage*; D015444:Exercise / Q000502:physiology*; D005990:Glycerol / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood; D008066:Lipolysis; D008297:Male; D010101:Oxygen Consumption; D014280:Triglycerides / Q000032:analysis; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D007328:Insulin; D014280:Triglycerides; D005990:Glycerol