title: Expression and function of Annexin II in lung cancer tissue.
abstract: OBJECTIVE
  To explore the expression of Annexin II and its relationship with the cell differentiation, proliferation in lung cancer.
  
  
  METHODS
  RT-PCR and Western blot assays were used to detect the expression of Annexin II in lung cancer tissues and cell lines.
  
  
  RESULTS
  Annexin II was significantly up-regulated in lung cancer tissues, and in lung cancer cell lines, Annexin II had higher mRNA and protein expressions.
  
  
  CONCLUSIONS
  Annexin II is up-regulated in lung cancer, suggesting that the Annexin II has a potential value in the human lung cancer.
authors: First Affiliated Hospital of Xinxiang Medical University, Henan, China.
authors: Jun-Wei
authors: JW
authors: Cui
authors: Yong-Liang
authors: YL
authors: Wang
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D017306:Annexin A2 / Q000032:analysis / Q000096:biosynthesis* / Q000235:genetics / Q000378:metabolism; D015153:Blotting, Western; D002454:Cell Differentiation / Q000502:physiology; D048708:Cell Growth Processes / Q000502:physiology; D045744:Cell Line, Tumor; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000737:chemistry / Q000378:metabolism* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012333:RNA, Messenger / Q000032:analysis / Q000096:biosynthesis / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D015854:Up-Regulation
chemical_list: D017306:Annexin A2; D012333:RNA, Messenger