title: [Genetics of ischemic stroke].
abstract: Stroke is one of the most widespread causes of mortality und disability worldwide. Around 80 % of strokes are ischemic and different forms of intracranial bleeding account for the remaining cases. Monogenic stroke disorders are rare but the diagnosis may lead to specific therapeutic consequences for the affected patients who are predominantly young. In common sporadic stroke, genetic factors play a role in the form of susceptibility genes. Their discovery may give rise to new therapeutic options in the future.
authors: Institut für Schlaganfall- und Demenzforschung (ISD), Max-Lebsche-Platz 30, 81377, München, Deutschland. andreas.gschwendtner@med.uni-muenchen.de
authors: A
authors: A
authors: Gschwendtner
authors: M
authors: M
authors: Dichgans
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D046589:CADASIL / Q000235:genetics / Q000401:mortality / Q000628:therapy; D002423:Cause of Death; D002544:Cerebral Infarction / Q000235:genetics* / Q000401:mortality; D002648:Child; D003430:Cross-Sectional Studies; D004252:DNA Mutational Analysis; D004185:Disability Evaluation; D000795:Fabry Disease / Q000175:diagnosis / Q000235:genetics; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005820:Genetic Testing; D055106:Genome-Wide Association Study; D005838:Genotype; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D020521:Stroke / Q000235:genetics* / Q000401:mortality / Q000628:therapy; D016019:Survival Analysis