title: Effect of crop protection and fertilization regimes used in organic and conventional production systems on feed composition and physiological parameters in rats.
abstract: Very little is known about the effects of an organic or conventional diet on animal physiology and health. Here, we report the effect of contrasting crop protection (with or without chemosynthetic pesticides) and fertilization (manure or mineral fertilizers) regimes on feed composition and growth and the physiological parameters of rats. The use of manure instead of mineral fertilizers in feed production resulted in lower concentrations of protein (18.8 vs 20.6%) and cadmium (3.33 vs 4.92 μg/100 g) but higher concentrations of polyphenols (1.46 vs 0.89 g/100 g) in feeds and higher body protein (22.0 vs 21.5%), body ash (3.59 vs 3.51%), white blood cell count (10.86 vs 8.19 × 10³/mm³), plasma glucose (7.23 vs 6.22 mmol/L), leptin (3.56 vs 2.78 ng/mL), insulin-like growth factor 1 (1.87 vs 1.28 μg/mL), corticosterone (247 vs 209 ng/mL), and spontaneous lymphocyte proliferation (11.14 vs 5.03 × 10³ cpm) but lower plasma testosterone (1.07 vs 1.97 ng/mL) and mitogen stimulated proliferation of lymphocytes (182 vs 278 × 10³ cpm) in rats. There were no main effects of crop protection, but a range of significant interactions between fertilization and crop protection occurred.
authors: Department of Functional & Organic Food & Commodities, Faculty of Human Nutrition and Consumer Sciences, Warsaw University of Life Sciences, Nowoursynowska 159c, 02-776 Warsaw, Poland. dominika.srednicka-tober@newcastle.ac.uk
authors: Dominika
authors: D
authors: Srednicka-Tober
authors: Marcin
authors: M
authors: Barański
authors: Joanna
authors: J
authors: Gromadzka-Ostrowska
authors: Krystyna
authors: K
authors: Skwarło-Sońta
authors: Ewa
authors: E
authors: Rembiałkowska
authors: Jana
authors: J
authors: Hajslova
authors: Vera
authors: V
authors: Schulzova
authors: Ismail
authors: I
authors: Cakmak
authors: Levent
authors: L
authors: Öztürk
authors: Tomasz
authors: T
authors: Królikowski
authors: Katarzyna
authors: K
authors: Wiśniewska
authors: Ewelina
authors: E
authors: Hallmann
authors: Elżbieta
authors: E
authors: Baca
authors: Mick
authors: M
authors: Eyre
authors: Håvard
authors: H
authors: Steinshamn
authors: Teresa
authors: T
authors: Jordon
authors: Carlo
authors: C
authors: Leifert
mesh_terms: D000383:Agriculture / Q000379:methods*; D000821:Animal Feed / Q000032:analysis*; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001823:Body Composition; D049109:Cell Proliferation / Q000187:drug effects; D003345:Corticosterone / Q000097:blood; D018556:Crops, Agricultural / Q000737:chemistry; D005260:Female; D005308:Fertilizers; D007334:Insulin-Like Growth Factor I / Q000378:metabolism; D020738:Leptin / Q000097:blood; D007958:Leukocyte Count; D008214:Lymphocytes / Q000166:cytology / Q000378:metabolism; D008297:Male; D058871:Organic Agriculture / Q000379:methods*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D001786:Blood Glucose; D005308:Fertilizers; D020738:Leptin; C548904:insulin-like growth factor-1, rat; D007334:Insulin-Like Growth Factor I; D003345:Corticosterone