title: The association of serum prolidase activity with developmental dysplasia of the hip.
abstract: The purpose of this study was to evaluate serum prolidase activity in patients with developmental dysplasia of the hip (DDH). Prolidase enzyme activity was measured spectrophotometrically to pointing out the collagen metabolism. The prolidase activity in patients with DDH was significantly higher than that in the control group (p = 0.002). Furthermore, there was positive correlation between prolidase activity and dysplasia level. Increased serum prolidase activity may have played a role in the presence of DDH. We therefore hypothesized that the increased prolidase activity related to collagen turnover may be associated with etiopathogenesis and/or the progression of the disease.
authors: Department of Physical Medicine and Rehabilitation, Research Hospital, Harran University, Sanliurfa, Turkey.
authors: N
authors: N
authors: Soran
authors: O
authors: O
authors: Altindag
authors: N
authors: N
authors: Aksoy
authors: H
authors: H
authors: Cakır
authors: A
authors: A
authors: Taşkın
authors: M
authors: M
authors: Soran
authors: E
authors: E
authors: Işıkan
mesh_terms: D000293:Adolescent; D002648:Child; D003094:Collagen / Q000378:metabolism; D004150:Dipeptidases / Q000378:metabolism*; D018450:Disease Progression; D005260:Female; D006618:Hip Dislocation, Congenital / Q000201:enzymology*; D006801:Humans; D008297:Male
chemical_list: D003094:Collagen; D004150:Dipeptidases; C022449:proline dipeptidase