title: Primary brain tumour epidemiology in Georgia: first-year results of a population-based study.
abstract: A population-based cohort study was initiated in Georgia in March 2009 to collect epidemiologic data of malignant and non-malignant primary brain tumours. During the first year, 473 incident cases were identified. For a population of 4.3 million, the annual incidence rate was 10.25 per 100,000 inhabitants, age-standardized to the year 2000 US population. Non-malignant tumours constituted about 66 % of all tumours. Males accounted for 40 % and females for 60 % of the cases. Crude incidence rates by histology were highest for meningiomas (2.92/100,000), pituitary adenoma (1.16/100,000) and glioblastomas (0.64/100,000), which was in agreement with the frequency of reported histology: meningiomas--45.2 %, pituitary adenoma--18.0 % and glioblastomas--9.9 %. The age-standardized incidence rates were higher among females than males for all primary brain tumours (11.05 vs. 8.44/100,000) as well as for individual histologies except for glioblastoma and several other neuroepithelial tumours. Some differences compared with 2004-2005 Central Brain Tumor Registry of the United States data may be explained by a higher percentage of unclassified tumours (37 %) in our study. We suggest further studies to clarify the nature of this discrepancy.
authors: Department of Neurology & Neurosurgery, Faculty of Medicine, Tbilisi State University, Tbilisi, 0112, Georgia. epigeo@hotmail.com
authors: David
authors: D
authors: Gigineishvili
authors: Nino
authors: N
authors: Shengelia
authors: Giorgi
authors: G
authors: Shalashvili
authors: Sabine
authors: S
authors: Rohrmann
authors: Alexander
authors: A
authors: Tsiskaridze
authors: Roman
authors: R
authors: Shakarishvili
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D005846:Georgia (Republic) / Q000453:epidemiology; D005909:Glioblastoma / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008577:Meningeal Neoplasms / Q000453:epidemiology*; D008875:Middle Aged; D018302:Neoplasms, Neuroepithelial / Q000453:epidemiology*; D010911:Pituitary Neoplasms / Q000453:epidemiology*; D011379:Prognosis; D011446:Prospective Studies; D055815:Young Adult