title: Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma.
abstract: Occult hepatitis B (OBI) is caused by a persistent low-level replication of HBV. Like overt HBV infection, OBI can be associated with the integration of HBV sequences into the host genome and has a substantial clinical relevance for patients who are severely immunosuppressed for long durations. We present the case of a patient with a diffuse large B-cell non-Hodgkin lymphoma and OBI who developed a hepatocellular carcinoma with a fulminant clinical course following the administration of rituximab plus CHOP.
authors: Department of Medical Oncology (Pad. H 5° Piano), University of Messina, Via Consolare Valeria Road 98125 Messina, Italy.
authors: Vincenzo
authors: V
authors: Pitini
authors: Massimo
authors: M
authors: Rizzo
authors: Carmela
authors: C
authors: Arrigo
authors: Patrizia
authors: P
authors: Mondello
authors: Giuseppe
authors: G
authors: Altavilla