title: Anaphylaxis in pregnancy: a rare cause of neonatal mortality.
abstract: Anaphylaxis is a rare condition in pregnancy. Drugs are the aetiological agents most often implicated. Maternal anaphylaxis can lead to significant fetal morbidity and even mortality if uterine perfusion and maternal oxygenation are compromised. Significant risk of neonatal neurological damage or death can occur even when the maternal clinical outcome is favourable. The authors present the case of a newborn, born at gestational age of 29 weeks, who died at 11 days of life with hypoxic-ischaemic cerebral injuries as a consequence of maternal anaphylaxis following the administration of amoxicillin in the community setting.
authors: Department of Pediatrics, Central Hospital of Funchal, Portugal. berenguer.alberto@gmail.com
authors: Alberto
authors: A
authors: Berenguer
authors: Alexandra
authors: A
authors: Couto
authors: Vera
authors: V
authors: Brites
authors: Rosário
authors: R
authors: Fernandes
mesh_terms: D000658:Amoxicillin / Q000009:adverse effects*; D000707:Anaphylaxis / Q000139:chemically induced* / Q000150:complications; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000209:etiology*; D007231:Infant, Newborn; D007234:Infant, Premature; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced*; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D000658:Amoxicillin