title: Current glycaemic control has no impact  on the advancement of diabetic neuropathy.
abstract: The aim of the study was to assess the association between glycemic control understanding as a glycated haemoglobin level and indices of diabetic neuropathy.
  
  
  METHODS
  We evaluated 204 patients with diabetes (type 1 - 29; type 2 - 175). Glycated haemoglobin was determined using The Diabetes Control and Complications Trial/ National Glycohemoglobin Standardization Program method. Evaluation of complaints from the lower extremities was based on the Neuropathy Syndrome Total Score questionnaire. We used a mono lament for evaluation of touch sensation (Semmes-Weinstein 5.07-10 g), a 128 Hz calibrated tune-fork for the vibration perception test, Tip-Therm to assess temperature sensation.
  
  
  RESULTS
  The mean glycated haemoglobin level was assessed on 8.53±1.87%. The mean Neuropathy Syndrome Total Score: 11.45±6.37. Decreased sensation of touch on both sides was determined in 30% of cases, decreased sensation of temperature in 59% and decreased sensation of vibration in 30%. For Neuropathy Syndrome Total Score and glycated haemoglobin the Pearson's correlation test was 0.00910 (p≈0.99), Spearman's rank correlation test was 0.00523 (p≈0.95). Persons with sensation deficits and neuropathy symptoms had not significantly higher (Neuropathy Syndrome Total Score, temperature sensation disturbances) and not significantly lower (vibration and touch) glycated haemoglobin level compared to patients without neuropathy.
  
  
  CONCLUSIONS
  There is no correlation between prevalence and advancement of sensorial neuropathy and current diabetes control in patients with long-term established diabetes.
authors: Diabetology Ward, Institute of Rural Health, Lublin, Poland. piotr.dziemidok@op.pl
authors: Piotr
authors: P
authors: Dziemidok
authors: Grzegorz
authors: G
authors: Szcześniak
authors: Ewa
authors: E
authors: Kostrzewa-Zabłocka
authors: Piotr
authors: P
authors: Paprzycki
authors: Anna
authors: A
authors: Korzon-Burakowska
mesh_terms: D000328:Adult; D000368:Aged; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000453:epidemiology / Q000503:physiopathology*; D017719:Diabetic Foot / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction; D011044:Poland / Q000453:epidemiology; D011237:Predictive Value of Tests; D015995:Prevalence; D012684:Sensory Thresholds; D013697:Thermosensing; D014110:Touch; D014732:Vibration
chemical_list: D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human