title: Stimuli-sensitive layer-by-layer (LbL) self-assembly systems: targeting and biosensory applications.
abstract: Stimuli-sensitive layer-by-layer (LbL) self-assembly systems have generated much interest among researchers worldwide due to the simplicity of the process by which they are produced and their numerous applications in drug delivery. LbL self-assembly systems involve simple alternative adsorption of oppositely charged polyelectrolytes on core materials and are thus considered to be promising tools for drug delivery and biosensing. Here, we discuss the latest findings from research into LbL systems, with special emphasis on drug delivery systems. This review highlights various stimuli-responsive LbL systems and their targeting and biosensory applications. For the convenience of readers, these stimuli-responsive LbL systems are classified as exogenous stimuli-responsive LbL systems and endogenous stimuli-responsive LbL systems.
authors: Department of Pharmaceutics, H R Patel Institute of Pharmaceutical Education and Research, Karwand Naka, Shirpur, Dist-Dhule-425 405, Maharashtra, India. pkdesh@rediffmail.com
authors: Prashant K
authors: PK
authors: Deshmukh
authors: Ketan P
authors: KP
authors: Ramani
authors: Saurabh S
authors: SS
authors: Singh
authors: Avinash R
authors: AR
authors: Tekade
authors: Vivekanand K
authors: VK
authors: Chatap
authors: Ganesh B
authors: GB
authors: Patil
authors: Sanjay B
authors: SB
authors: Bari
mesh_terms: D000327:Adsorption; D015374:Biosensing Techniques / Q000379:methods*; D004337:Drug Carriers / Q000737:chemistry; D004339:Drug Compounding / Q000379:methods*; D016503:Drug Delivery Systems / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry; D011108:Polymers / Q000737:chemistry
chemical_list: D004337:Drug Carriers; D011108:Polymers