title: Successful treatment of digital tip necrosis in rheumatoid vasculitis with anti-CD20 antibody rituximab.
abstract: We report a successful treatment with rituximab in the case of rheumatoid vasculitis causing digital tips necrosis in exacerbated rheumatoid arthritis. The vasculitis lesions did not respond completely to intravenous methylprednisolone and cyclophosphamide but responded on rituximab treatment. Deep necrosis of a digital tip resolved entirely after completing a course of rituximab.
authors: Division of Rheumatology, Departments of Internal Medicine and Gerontology, College of Medicine, Jagiellonian University, Krakow, Poland. mariusz.korkosz@mp.pl
authors: Mariusz
authors: M
authors: Korkosz
authors: Jarosław
authors: J
authors: Królczyk
authors: Dorota
authors: D
authors: Telesińska-Jasiówka
authors: Tomasz
authors: T
authors: Grodzicki
mesh_terms: D058846:Antibodies, Monoclonal, Murine-Derived / Q000627:therapeutic use*; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005385:Fingers / Q000473:pathology*; D006801:Humans; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D009336:Necrosis; D056653:Rheumatoid Vasculitis / Q000188:drug therapy* / Q000473:pathology; D000069283:Rituximab; D017211:Treatment Failure; D016896:Treatment Outcome
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D018501:Antirheumatic Agents; D000069283:Rituximab; D003520:Cyclophosphamide; D008775:Methylprednisolone