title: Uterine rupture in a nulliparous woman with septate uterus of the second trimester pregnancy and review in literature.
abstract: BACKGROUND
  Uterine rupture (UR) in early pregnancy in nulliparous women is a rare and unpredictable occurrence with high maternal morbidity and fatal fetal outcomes. Intrauterine anomalies could be the primum movens of this dangerous condition and underestimated in the literature.
  
  
  METHODS
  An uncommon case of uterine rupture at the 23rd week of gestation in a nulliparous woman, who became pregnant before the resection of an uterine septum. To provide more insight into the possible risk factors, a literature review was performed.
  
  
  CONCLUSIONS
  Loss of pregnancy is common, despite prompt uterine repair. In all cases reviewed abdominal pain characterized by indistinct vague symptoms constitutes the initial symptom of this obstetrical life threatening condition.
  
  
  CONCLUSIONS
  The current case highlights the association of curettage and septate uterus as a risk factor for UR in the second trimester of pregnancy. It's reasonable that obstetricians must take into account that common gastrointestinal tract problems might be an indicator of the initial weakness of uterine wall leading to the rupture, which is unpredictable all of cases reviewed.
authors: Department of Obstetrics and Gynecology, 2° Operative Unit, University of Bari Aldo Moro, Policlinico, Bari, Italy; Department of Obstetrics and Gynecology, Hospital of Sondrio, Sondrio, Italy; Department of Obstetrics and Gynecology, Manzoni Hospital, Lecco, Italy. Electronic address: damiani14@alice.it.
authors: Gianluca Raffaello
authors: GR
authors: Damiani
authors: Maria
authors: M
authors: Gaetani
authors: Stefano
authors: S
authors: Landi
authors: Loredana
authors: L
authors: Lacerenza
authors: Mario
authors: M
authors: Barnaba
authors: Domenico
authors: D
authors: Spellecchia
authors: Antonio
authors: A
authors: Pellegrino