title: Trichomonas vaginalis vaginitis in obstetrics and gynecology practice: new concepts and controversies.
abstract: Trichomonas vaginalis (TV) is the most common curable sexually transmitted infection worldwide. Annually, 7.4 million new infections are estimated in the United States, which is greater than combined new cases of Chlamydia, gonorrhea, and syphilis. Serious adverse reproductive health outcomes including pregnancy complications, pelvic inflammatory disease, and an increased risk of HIV acquisition have been linked to TV infection. There are several sensitive and specific diagnostic tests available, including a newly approved nucleic acid amplification test (NAAT) that utilizes the same instrumentation platform and clinical sample as Chlamydia and gonorrhea tests. In this article, we review TV pathogenicity, adverse reproductive health outcomes, detection, and treatment followed by clinical scenarios for which TV diagnosis may prove useful in obstetrics and gynecology practice.
authors: Division of Gynecologic Specialties, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. colemanj@jhmi.edu
authors: Jenell S
authors: JS
authors: Coleman
authors: Charlotte A
authors: CA
authors: Gaydos
authors: Frank
authors: F
authors: Witter
mesh_terms: D000890:Anti-Infective Agents / Q000008:administration & dosage; D060085:Coinfection / Q000517:prevention & control; D037001:Directive Counseling / Q000379:methods; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000517:prevention & control / Q000635:transmission; D006801:Humans; D008795:Metronidazole / Q000008:administration & dosage*; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D000292:Pelvic Inflammatory Disease / Q000209:etiology / Q000517:prevention & control; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control; D011256:Pregnancy Outcome; D034121:Reproductive Health Services / Q000458:organization & administration*; D012749:Sexually Transmitted Diseases / Q000150:complications / Q000517:prevention & control; D014247:Trichomonas Vaginitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000635:transmission; D014246:Trichomonas vaginalis / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity; D014481:United States / Q000453:epidemiology; D016387:Women's Health
chemical_list: D000890:Anti-Infective Agents; D008795:Metronidazole