title: [Interaction of both hypertriglyceridemic waist and impaired fasting glucose on the incidence of diabetes mellitus].
abstract: OBJECTIVE
  To study the use of hypertriglyceridemic waist (HTGW) to predict the occurrence of diabetes. Also to independently study whether there was an interaction between HTGW and impaired fasting glucose impaired fasting glucose (IFG) on the cause of diabetes.
  
  
  METHODS
  We undertook a cohort study based on data from the "Prevention of Multiple Metabolic Disorders and Metabolic Syndrome (MS) Study in Jiangsu Province, China". We used the logistic regression model to analyze the relations between both HTGW, IFG and diabetes mellitus and to evaluate the multiplied interaction between HTGW and IFG to include product terms method. Counting additive interaction was carried out under the Excel Calculation Sheet, compiled by Anderson and his colleagues.
  
  
  RESULTS
  After adjusted for general risk factors and baseline fasting plasma glucose (FPG), results showed that subjects with HTGW had a 2.10 (95% CI: 1.36 - 3.25) adjusted relative risk (HR) of developing a diabetes when compared with those individuals without HTGW at the baseline study. When IFG was stratified, participants with HTGW were significantly associated with diabetes, regardless of IFG. The multi-adjusted HRs of diabetes were 3.09 (1.70 - 5.61) and 2.09 (1.08 - 4.02), respectively. Compared to the participants with non-HTGW and their FPG level below the threshold, those having HTGW and their FPG level was above the threshold, had the highest adjusted HR values [12.05 (95% CI: 6.89 - 21.07)]. Data from the additive interaction analysis showed that RERI as 7.00 (95% CI: 0.49 - 13.51), AP as 0.57 (95% CI: 0.32 - 0.82) and SI as 2.66 (95% CI: 1.36 - 5.21).
  
  
  CONCLUSIONS
  HTGW could predict the occurrence of diabetes, independent from IFG while the presence of HTGW with IFG could have an additive interaction on the cause of diabetes.
authors: Department of Radiology and Public Health, Medical College of Soochow University, Suzhou 215123, China.
authors: Qiu-rong
authors: QR
authors: Zhu
authors: Xiao-shu
authors: XS
authors: Hu
authors: Ming
authors: M
authors: Wu
authors: Zheng-yuan
authors: ZY
authors: Zhou
authors: Jing-chao
authors: JC
authors: Liu
authors: Wen-shu
authors: WS
authors: Luo
authors: Yi
authors: Y
authors: Ding
authors: Zhi-rong
authors: ZR
authors: Guo
mesh_terms: D000328:Adult; D015331:Cohort Studies; D003920:Diabetes Mellitus / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology; D005260:Female; D018149:Glucose Intolerance; D006801:Humans; D064250:Hypertriglyceridemic Waist; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012307:Risk Factors