title: Direct lactonization of 2-arylacetic acids through Pd(II)-catalyzed C-H activation/C-O formation.
abstract: Palladium-catalyzed direct lactonization of 2-arylacetic acids through a reaction sequence that includes C-H activation/C-O formation is reported. This method provides a concise and efficient pathway to synthesize fully functionalized benzofuranone derivatives, which are highly relevant to bioactive natural and synthetic products.
authors: Beijing National Laboratory for Molecular Sciences (BNLMS), College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, China.
authors: Mingyu
authors: M
authors: Yang
authors: Xingyu
authors: X
authors: Jiang
authors: Wen-Juan
authors: WJ
authors: Shi
authors: Qi-Lei
authors: QL
authors: Zhu
authors: Zhang-Jie
authors: ZJ
authors: Shi
mesh_terms: D000085:Acetates / Q000737:chemistry*; D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry; D002384:Catalysis; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D000085:Acetates; D001572:Benzofurans; D002264:Carboxylic Acids; D010165:Palladium