title: Auricular chondritis and thrombotic microangiopathy: an unusual combination revealing systemic lupus erythematosus.
abstract: Thrombotic microangiopathy is a severe disorder, which is a cause of stroke in young patients. Etiologic investigations are mandatory to diagnose underlying disease. Systemic lupus erythematosus is one of the diseases, which can be associated with thrombotic microangiopathy. Although lupus diagnosis is usually easy, relying on characteristic clinical manifestations, rare symptoms can be misinterpreted. We report here a case of polychondritis, which was the first manifestation of a lupus-associated thrombotic microangiopathy.
authors: AP-HP, Department of Internal Medicine, Bicêtre University Medical Center, 78, rue du Général-Leclerc, 94275 Le-Kremlin-Bicêtre, France.
authors: Nathalia
authors: N
authors: Bellon
authors: Nadia
authors: N
authors: Anguel
authors: Christophe
authors: C
authors: Vandendries
authors: Cecile
authors: C
authors: Goujard
authors: Olivier
authors: O
authors: Lambotte
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D002357:Cartilage Diseases / Q000453:epidemiology* / Q000209:etiology* / Q000628:therapy; D015897:Comorbidity; D004359:Drug Therapy, Combination; D004425:Ear Cartilage; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D010951:Plasma Exchange; D011241:Prednisone / Q000627:therapeutic use; D057049:Thrombotic Microangiopathies / Q000453:epidemiology* / Q000209:etiology* / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D006886:Hydroxychloroquine; D011241:Prednisone
keywords: Chondritis; Lupus; Polychondritis; Thrombotic microangiopathy