title: Adherence to treatment, emotional state and quality of life in patients with end-stage renal disease undergoing dialysis.
abstract: BACKGROUND
  A low rate of adherence to treatment is a widespread problem of great clinical relevance among dialysis patients. The objective of the present study is to determine the relationship between adherence, emotional state (depression, anxiety, and perceived stress), and health-related quality of life (HRQOL) in renal patients undergoing dialysis.
  
  
  METHODS
  Two patient groups (30 in hemodialysis and 31 in peritoneal dialysis) participated in this study. We evaluated aspects of adherence, depression, anxiety, perceived stress, and HRQOL with self-report and standardized instruments.
  
  
  RESULTS
  Peritoneal dialysis patients reported significantly higher levels of adherence to treatment and better HRQOL in Physical Function and Bodily Pain domains. Depression level is associated with HRQOL indicators. We did not find any differences regarding specific adherence to antihypertensive and phosphate binder drugs or in psychological variables depending on the modality of dialysis. Patients with adherence to antihypertensive drugs show better physical HRQOL. The predictors of HRQOL in dialysis patients were: work, gender and depression.
  
  
  CONCLUSIONS
  Our results suggest that the modality of dialysis does not differentially affect the emotional state or specific adherence to drugs, but it is nevertheless related to their overall adherence to treatment and to their HRQOL.
authors: Hospital Universitario La Paz, Madrid, Spain. helenagllana@hotmail.com
authors: Helena
authors: H
authors: García-Llana
authors: Eduardo
authors: E
authors: Remor
authors: Rafael
authors: R
authors: Selgas
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001007:Anxiety / Q000453:epidemiology* / Q000209:etiology; D003863:Depression / Q000453:epidemiology* / Q000209:etiology; D004644:Emotions; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000523:psychology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000523:psychology*; D010530:Peritoneal Dialysis / Q000523:psychology; D011788:Quality of Life; D006435:Renal Dialysis / Q000523:psychology*; D051436:Renal Insufficiency, Chronic; D013315:Stress, Psychological / Q000453:epidemiology* / Q000209:etiology; D055815:Young Adult