title: [Hyperinsulinemic hypoglycemia of the infancy: analysis of clinical data from a Brazilian sample].
abstract: OBJECTIVE
  To review the presentation of hyperinsulinemic hypoglycemia of the infancy (HHI), its treatment and histology in Brazilian pediatric endocrinology sections.
  
  
  METHODS
  The protocol analyzed data of birth, laboratory results, treatment, surgery, and pancreas histology.
  
  
  RESULTS
  Twenty-five cases of HHI from six centers were analyzed: 15 male, 3/25 born by vaginal delivery. The average age at diagnosis was 10.3 days. Glucose and insulin levels in the critical sample showed an average of 24.7 mg/dL and 26.3 UI/dL. Intravenous infusion of the glucose was greater than 10 mg/kg/min in all cases (M:19,1). Diazoxide was used in 15/25 of the cases, octreotide in 10, glucocorticoid in 8, growth hormone in 3, nifedipine in 2 and glucagon in 1. Ten of the cases underwent pancreatectomy and histology results showed the diffuse form of disease.
  
  
  CONCLUSIONS
  This is the first critic review of a Brazilian sample with congenital HHI.
authors: Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, SP, Brasil. liberat@famerp.br
authors: Raphael Del Roio
authors: Rdel R
authors: Liberatore Junior
authors: Alcinda Aranha
authors: AA
authors: Negri
authors: Carlos Eduardo
authors: CE
authors: Martinelli Junior
authors: Cristiane
authors: C
authors: Kochi
authors: Ivani Novato
authors: IN
authors: Silva
authors: Paulo Ferrez
authors: PF
authors: Collett-Solberg
mesh_terms: D001786:Blood Glucose / Q000032:analysis; D001938:Brazil; D044903:Congenital Hyperinsulinism / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007328:Insulin / Q000097:blood; D008297:Male; D008499:Medical Records; D010180:Pancreatectomy
chemical_list: D001786:Blood Glucose; D007328:Insulin