title: Observations of periwound skin protection in venous ulcers:  a comparison of treatments.
abstract: OBJECTIVE
  The objective of this study was to examine the effectiveness of 2 products on venous ulcer periwound skin.
  
  
  METHODS
  This was a descriptive comparative study.
  
  
  METHODS
  An outpatient wound care clinic in a rural Midwestern area of the United States.
  
  
  METHODS
  Participants included a retrospective group of 50 patients and a prospective group of 28 patients.
  
  
  METHODS
  The intervention compared the experimental product (Remedy Nutrashield; Medline Industries, Mundelein, Illinois) versus Cavilon Moisturizing Lotion (3M, St Paul, Minnesota).
  
  
  METHODS
  The mean outcome measures were a decrease in periwound and ulcer size.
  
  
  RESULTS
  For the periwound size, the estimated rates of change were as follows: 0.092 (SE, 0.021) cm/d and -0.026 (SE, 0.014) cm/d for products B and A groups, respectively. The decrease for the experimental group was significantly greater than the attenuated decrease for the retrospective cases (t297 = -2.57, P = .01), and the decrease for product B group was also significantly different from zero (t76 = -4.34, P < .0001). For the ulcer size model, the estimated rates of change were -0.272 (SE, 0.102) cm/d and -0.130 (SE, 0.067) cm/d for the experimental and retrospective groups, respectively. The rate for the experimental group was significantly less than zero (t76 = -2.67, P = .009), but there was no significant difference between prospective and retrospective cases in the rates of reduction in ulcer size (t308 = -1.16, P = .25).
  
  
  CONCLUSIONS
  The results of this study illustrate how the integrity of the periwound skin may be an important determinant in decreasing periwound and ulcer size.
authors: University of North Dakota College of Nursing, Grand Forks, North Dakota, USA.
authors: Susan M
authors: SM
authors: Hunter
authors: Diane
authors: D
authors: Langemo
authors: Patricia
authors: P
authors: Thompson
authors: Darlene
authors: D
authors: Hanson
authors: Julie
authors: J
authors: Anderson
authors: In Eui
authors: IE
authors: Oh
authors: Rolf
authors: R
authors: Paulson
authors: Dan
authors: D
authors: Rustvang
authors: Seth
authors: S
authors: Dorman
authors: David L
authors: DL
authors: Roth
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003879:Dermatologic Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011446:Prospective Studies; D012189:Retrospective Studies; D063465:Skin Cream / Q000627:therapeutic use*; D016896:Treatment Outcome; D014647:Varicose Ulcer / Q000188:drug therapy* / Q000473:pathology*; D014945:Wound Healing
chemical_list: D003879:Dermatologic Agents