title: [Surgical management and reconstruction of petrous internal carotid artery involved in malignant tumors of lateral skull base].
abstract: OBJECTIVE
  To investigate the feasibility of reconstruction of internal carotid artery after ablation of malignant tumors in lateral skull base.
  
  
  METHODS
  Four male patients with malignant tumors in lateral skull base involved internal carotid artery underwent surgical treatment during Jan 2006 to Jan 2009 were retrospectively analyzed. MRI, CT and DSA were performed in all patients and showed that petrous internal carotid arteries (PICAs) were invaded, with luminal narrow. After radical dissection of tumors and the invaded PICAs, saphenous veins were used to reconstruct the PICAs. All cases were applied with postoperative concomitant radiochemotherapy. Three cases underwent total resection of temporal bone and one case underwent sub-total resection of temporal bone. Retrusion of facial nerve was performed in one case and reconstruction of facial nerve in three cases; Resection of sigmoid sinus and jugular foramen was performed in three cases. Resection and repair of meninges were performed in three cases. Free abdominal rectus and latissimus dorsi muscle myocutaneous flaps were used to repair the defect of lateral skull base and the flaps were well survived.
  
  
  RESULTS
  No significant neurovascular complications occurred in the patients. Postoperative DSA showed that the reconstructed PICAs were in well conditions. Follow up showed two patients survived tumor-free for five years, one patient had recurrence three years after operation and survived with tumor, and one patient died of recurrence one year after operation.
  
  
  CONCLUSIONS
  Reconstruction of PICA by saphenous vein offered the possibility of radical resection of malignant tumors in lateral skull base involved PICAs.
authors: Department of Otorhinolaryngology Head and Neck Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.
authors: Min-hui
authors: MH
authors: Zhu
authors: Hong-liang
authors: HL
authors: Zheng
authors: Shi-cai
authors: SC
authors: Chen
authors: Cai-yun
authors: CY
authors: Zhang
authors: Dong-hui
authors: DH
authors: Chen
authors: Xiang
authors: X
authors: Feng
mesh_terms: D000328:Adult; D002343:Carotid Artery, Internal / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D019292:Skull Base Neoplasms / Q000473:pathology / Q000601:surgery*; D014656:Vascular Surgical Procedures; D055815:Young Adult