title: Parental attitudes toward fertility preservation in boys with cancer: context of different risk levels of infertility and success rates of fertility restoration.
abstract: OBJECTIVE
  To measure the parental attitudes toward fertility preservation in boys with cancer.
  
  
  METHODS
  Retrospective cohort study.
  
  
  METHODS
  Questionnaire survey via regular mail.
  
  
  METHODS
  A total of 465 families whose sons were already treated for cancer.
  
  
  METHODS
  The questionnaire was designed for two groups based on child's age at the time of cancer diagnosis: <12 and ≥12 years old.
  
  
  METHODS
  Descriptive statistics regarding a positive or negative attitude of parents toward fertility preservation options in the context of different risk levels of infertility and success rates of fertility restoration.
  
  
  RESULTS
  The response rate was 78%. Sixty-four percent of parents of boys ≥12 years old would agree to store sperm obtained by masturbation and/or electroejaculation, and 54% of parents of boys <12 years old would agree to store a testicular biopsy. If the risk of infertility or the success rate of fertility restoration were ≤20%, more than one-fourth of parents would still opt for fertility preservation.
  
  
  CONCLUSIONS
  All parents should be counseled about the risks of infertility due to cancer treatment, because many parents want to preserve their son's fertility even if the risk of becoming infertile or the chances on fertility restoration are low.
authors: Reproductive Biotechnology Research Center, Avicenna Research Institute, The Academic Center for Education, Culture and Research (ACECR), Tehran, Iran. hsadri@wakehealth.edu
authors: Hooman
authors: H
authors: Sadri-Ardekani
authors: Mohammad-Mehdi
authors: MM
authors: Akhondi
authors: Parvaneh
authors: P
authors: Vossough
authors: Haleh
authors: H
authors: Maleki
authors: Shirin
authors: S
authors: Sedighnejad
authors: Koorosh
authors: K
authors: Kamali
authors: Behzad
authors: B
authors: Ghorbani
authors: Madelon
authors: M
authors: van Wely
authors: Fulco
authors: F
authors: van der Veen
authors: Sjoerd
authors: S
authors: Repping
mesh_terms: D000293:Adolescent; D001294:Attitude to Health; D002648:Child; D002675:Child, Preschool; D005260:Female; D005298:Fertility; D059247:Fertility Preservation / Q000523:psychology* / Q000706:statistics & numerical data; D019337:Hematologic Neoplasms / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy; D006689:Hodgkin Disease / Q000453:epidemiology / Q000523:psychology / Q000628:therapy; D006801:Humans; D007248:Infertility, Male / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy*; D015470:Leukemia, Myeloid, Acute / Q000453:epidemiology / Q000523:psychology / Q000628:therapy; D008297:Male; D010290:Parents / Q000523:psychology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000453:epidemiology / Q000523:psychology / Q000628:therapy; D012189:Retrospective Studies; D012307:Risk Factors; D011795:Surveys and Questionnaires