title: Separation, interconversion, and insecticidal activity of the cis- and trans-isomers of novel hydrazone derivatives.
abstract: A series of cis- and trans-isomers of hydrazone derivatives were separated and analyzed through HPLC with diode-array detection and HPLC-MS/MS using ESI and ion trap MS. Two single crystals (A-5-1 and C-2-1) of the trans-isomers were obtained and determined using X-ray crystallography data, and the cis- to trans-isomerization under different conditions was discussed. Both of the cis- and trans-isomers of A-4 and A-5 exhibited good insecticidal activities against Plutella xylostella.
authors: State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang, P R China.
authors: Jian
authors: J
authors: Wu
authors: Chaoqun
authors: C
authors: Huang
authors: Jian
authors: J
authors: Wang
authors: Deyu
authors: D
authors: Hu
authors: Linhong
authors: L
authors: Jin
authors: Song
authors: S
authors: Yang
authors: Baoan
authors: B
authors: Song
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006835:Hydrazones / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D007536:Isomerism; D015394:Molecular Structure; D009036:Moths / Q000187:drug effects; D013329:Structure-Activity Relationship; D053719:Tandem Mass Spectrometry / Q000379:methods
chemical_list: D006835:Hydrazones; D007306:Insecticides