title: Gastroscopy-associated transmission of extended-spectrum beta-lactamase-producing Pseudomonas aeruginosa.
abstract: An unusual multi-drug-resistant Pseudomonas aeruginosa (MDR-PA) was isolated in four patients whilst hospitalized in a French teaching hospital between May and August 2011. All four patients had undergone an oesophago-gastro-duodenoscopy with the same gastroscope over a five-month period. This endoscope was associated with a culture positive for the MDR-PA. Observations of endoscope reprocessing identified deviations from the agreed processes: insufficient initial cleaning, shortening of the immersion time and brushing time, insufficient channel flushing, and inadequate drying prior to storage. Since withdrawing the gastroscope and institution of strict adherence to the agreed processes, no other MDR-PA cases have been isolated.
authors: Equipe Opérationnelle d'Hygiène, CHU de Reims, Reims, France; UFR Médecine, Université de Reims, Reims, France. obajolet@chu-reims.fr
authors: O
authors: O
authors: Bajolet
authors: D
authors: D
authors: Ciocan
authors: C
authors: C
authors: Vallet
authors: C
authors: C
authors: de Champs
authors: V
authors: V
authors: Vernet-Garnier
authors: T
authors: T
authors: Guillard
authors: L
authors: L
authors: Brasme
authors: G
authors: G
authors: Thiefin
authors: G
authors: G
authors: Cadiot
authors: F
authors: F
authors: Bureau-Chalot
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003428:Cross Infection / Q000382:microbiology / Q000635:transmission*; D004203:Disinfection / Q000379:methods; D024901:Drug Resistance, Multiple, Bacterial; D005602:France; D020699:Gastroscopes / Q000382:microbiology; D005773:Gastroscopy / Q000009:adverse effects*; D019983:Guideline Adherence; D006784:Hospitals, Teaching; D006801:Humans; D017053:Infection Control / Q000379:methods; D008875:Middle Aged; D011552:Pseudomonas Infections / Q000382:microbiology / Q000635:transmission*; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000201:enzymology* / Q000302:isolation & purification; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001618:beta-Lactamases