title: [Remission of lymphoma-associated pure red cell aplasia after successful chemotherapy for B-cell lymphoma].
abstract: A 49-year-old man was diagnosed with pure red cell aplasia (PRCA) based on low reticulocyte count (0.1%) and near absence of erythroblasts in the bone marrow (BM). While a small number of CD20-positive large abnormal cells was observed in the BM, Multiplex PCR confirmed B cell monoclonality. Gallium scintigraphy showed abnormality only in the BM, and we made a diagnosis of PRCA secondary to BM-derived B-cell malignant lymphoma. He was treated with rituximab-combined CHOP therapy with subsequent resolution of both disorders. He was further treated with high dose chemotherapy with auto-PBSCT, sustaining complete remission of the PRCA and lymphoma.
authors: Department of Hematology, Shinko Hospital, Japan.
authors: Emiko
authors: E
authors: Sakane
authors: Hiroko
authors: H
authors: Tsunemine
authors: Hiroshi
authors: H
authors: Akasaka
authors: Kiminari
authors: K
authors: Ito
authors: Taiichi
authors: T
authors: Kodaka
authors: Yoshiko
authors: Y
authors: Takahashi
authors: Takayuki
authors: T
authors: Takahashi
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012010:Red-Cell Aplasia, Pure / Q000150:complications / Q000628:therapy*; D012074:Remission Induction; D014184:Transplantation, Homologous; D016896:Treatment Outcome