title: [Effect of different levels of glucose in the dialysate on the risk of hypoglycaemia during hemodialysis in diabetic patients].
abstract: BACKGROUND
  Hypoglycemia can occur during hemodialysis in diabetic chronic renal failure patients when using a dialysate without glucose. With dialysis solutions with glucose 90 mg/dL or more, this is preventable, but diabetic patients could present higher intradialytic glycemias.
  
  
  OBJECTIVE
  We tested a dialytic fluid with a lower level of glucose trying to prevent both hypo and hyperglycemia in these patients.
  
  
  METHODS
  Twenty diabetic individuals from our hemodialysis unit were submitted to 3 sessions with dialysis solutions with two different glucose concentrations--55 mg/dL (Phase 55), and 90 mg/dL (Phase 90)--and a glucose-free one (Phase ZERO). Plasma glucose levels were measured at five moments during each session--before and at 30, 60, 90 and 240 min. Results under 70 mg/dL were considered as hypoglycemia.
  
  
  RESULTS
  Three patients presented 6 episodes of hypoglycemia in Phase 55, but no patient presented any episode in Phase 90. In Phase ZERO, five patients presented 7 episodes.
  
  
  CONCLUSIONS
  This dialysate with a low level of glucose (55 mg/dL) did not prevent hypoglycemia episodes during hemodialysis in diabetic patients, these occurrences being similar to that when using a dialysate without glucose. The use of a 90 mg/dL glucose dialysis solution did not induce higher intradialytic glycemia levels than the other dialysis solutions.
authors: Departamento de Clínica Médica, Unidade de Medicina Renal, Hospital Universitário, Universidade Luterana do Brasil, Canoas, RS, Brasil. jb.nefro@gmail.com
authors: Jayme Eduardo
authors: JE
authors: Burmeister
authors: Juliana Fernandes
authors: JF
authors: Campos
authors: Diego da Rosa
authors: DR
authors: Miltersteiner
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D003920:Diabetes Mellitus / Q000097:blood*; D015314:Dialysis Solutions / Q000737:chemistry*; D005260:Female; D005947:Glucose / Q000032:analysis*; D006801:Humans; D007003:Hypoglycemia / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012307:Risk Factors; D013997:Time Factors
chemical_list: D001786:Blood Glucose; D015314:Dialysis Solutions; D005947:Glucose