title: Hospital-based surveillance for rotavirus gastroenteritis using molecular testing and immunoassay during the 2011 season in Botswana.
abstract: We describe rotavirus testing and clinical characteristics for children admitted with acute gastroenteritis during Botswana's 2011 rotavirus season. The rotavirus season extended from June to October with rotavirus-specific case fatality being 2.8%. Using molecular testing as reference, the immunochromatographic test had a sensitivity of 76.5% and specificity of 68.0%. Rotavirus vaccine may significantly reduce childhood morbidity and mortality in Botswana.
authors: Botswana-UPenn Partnership, Gaborone, Botswana.
authors: Henry
authors: H
authors: Welch
authors: Andrew P
authors: AP
authors: Steenhoff
authors: Unoda
authors: U
authors: Chakalisa
authors: Tonya
authors: T
authors: Arscott-Mills
authors: Loeto
authors: L
authors: Mazhani
authors: Margaret
authors: M
authors: Mokomane
authors: Sara
authors: S
authors: Foster-Fabiano
authors: Kathleen E
authors: KE
authors: Wirth
authors: Andrew
authors: A
authors: Skinn
authors: Jeffrey M
authors: JM
authors: Pernica
authors: Marek
authors: M
authors: Smieja
authors: David M
authors: DM
authors: Goldfarb
mesh_terms: D001902:Botswana / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005243:Feces / Q000821:virology; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D006761:Hospitals; D006801:Humans; D007118:Immunoassay; D007223:Infant; D025202:Molecular Diagnostic Techniques; D016133:Polymerase Chain Reaction; D011446:Prospective Studies; D062486:Public Health Surveillance; D012401:Rotavirus; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000821:virology