title: Racial disparities in left main stenting: insights from a real world inner city population.
abstract: BACKGROUND
  Left main coronary artery (LMCA) disease is associated with significant cardiovascular mortality. The data on patient characteristics' predicting outcomes after LMCA revascularization is sparse.
  
  
  METHODS
  A retrospective study of 227 patients with LMCA disease documented on coronary angiography from March 2000 to December 2008. Data included demographic variables, co-morbidities, cardiac function, and medications. Race was self-identified. The study outcome was a composite end-point including myocardial infarction (MI) and all-cause mortality. Cox proportional hazard analysis was performed to study the effect of various patient attributes including race and gender on the composite end-point.
  
  
  RESULTS
  Baseline characteristics were specifically compared between individuals who had the study outcome versus those who did not. Mean age was higher in the group with study outcomes when compared to the group without any outcomes (64.3 ± 11.8 years versus 59.2 ± 13.6 years; p = 0.013). After the final multivariate regression analysis, only African American (AA) race and age were found to be independent predictors of adverse cardiac outcome at the end of the first year (race-hazard ratio (HR) 3.82, 95% confidence interval (CI) 1.38-10.62, p = 0.010; age-HR 1.08, 95% CI 1.04-1.13, p < 0.001) and at the end of the study (race-HR 2.71, 95% CI 1.44-5.10, p = 0.002; age-HR 1.03, 95% CI 1.01-1.08, p = 0.017).
  
  
  CONCLUSIONS
  In our study of patients with unprotected LMCA disease, AA race, and age were significantly predictive of poor prognosis following revascularization, while gender had no predictive value in prognosticating cardiovascular mortality.
authors: Department of Cardiology, Detroit Medical Center, Detroit, Michigan 48823, USA. tamamns@yahoo.com
authors: Tamam
authors: T
authors: Mohamad
authors: Sidakpal S
authors: SS
authors: Panaich
authors: Anas
authors: A
authors: Alani
authors: Apurva
authors: A
authors: Badheka
authors: Maithili
authors: M
authors: Shenoy
authors: Bashar
authors: B
authors: Mohamad
authors: Eyas
authors: E
authors: Kanaan
authors: Omaima
authors: O
authors: Ali
authors: Mahir
authors: M
authors: Elder
authors: Theodore L
authors: TL
authors: Schreiber
mesh_terms: D000367:Age Factors; D044383:Black People; D003324:Coronary Artery Disease / Q000401:mortality / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008824:Michigan; D008875:Middle Aged; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000401:mortality; D011379:Prognosis; D012189:Retrospective Studies; D015607:Stents; D014505:Urban Population; D001741:Black or African American