title: Pregnancy and treatment outcome in a patient with left ventricular non-compaction.
abstract: Left ventricular non-compaction (LVNC) is a rare form of cardiomyopathy. This case reviews a woman with familial LVNC (EF 45%, NYHA class I, evidence of non-sustained ventricular tachycardia pre-pregnancy) who had significant decompensation with heart failure in the third trimester that required early delivery. Deterioration in symptoms and LV function 7 days after delivery required further hospitalization and aggressive treatment. Suppression of lactation with bromocriptine, together with standard heart failure management, has allowed recovery and return to full activities and work. Acknowledged adverse risk factors in LVNC are considered, and pre-pregnancy risk assessment is reviewed. There is no specific treatment for LVNC in pregnancy besides the usual management of dilated cardiomyopathy. This is the ninth case report of LVNC in pregnancy reported in the literature.
authors: Department of Cardiology, Norfolk and Norwich University Hospitals NHS Foundation Trust, Colney Lane, Norwich, UK.
authors: Rahul D
authors: RD
authors: Sawant
authors: Leisa J
authors: LJ
authors: Freeman
authors: Katherine P S
authors: KP
authors: Stanley
authors: Alistair
authors: A
authors: McKelvey
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D017298:Bisoprolol / Q000627:therapeutic use; D004232:Diuretics / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004452:Echocardiography; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D005665:Furosemide / Q000627:therapeutic use; D006333:Heart Failure / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D006352:Heart Ventricles; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use; D006801:Humans; D056830:Isolated Noncompaction of the Ventricular Myocardium / Q000175:diagnosis / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular; D011256:Pregnancy Outcome; D011263:Pregnancy Trimester, Third; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents; D004232:Diuretics; D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight; D005665:Furosemide; D017298:Bisoprolol