title: Efficacy of and effect on tooth sensitivity of in-office bleaching gel concentrations: a randomized clinical trial.
abstract: With the aim of reducing the side effects of in-office bleaching agents, less-concentrated hydrogen peroxide (HP) gels have been released by manufacturers. We evaluated the tooth sensitivity (TS) and bleaching efficacy (BE) of two HP concentrations in this study. Gels containing 35% and 20% HP (HP35 and HP20, respectively) were applied on teeth of 60 caries-free patients. Color was recorded at baseline and one week after the first and second bleaching sessions using the Vita Classical shade guide. TS was recorded on a 0-4 scale. BE at each weekly recall was evaluated by Kruskall-Wallis and Mann-Whitney tests (α=0.05). Absolute risk of TS and its intensity was evaluated by Fisher exact and Mann-Whitney tests, respectively (α=0.05). After two bleaching sessions, color change of approximately eight tabs was obtained with HP35; whereas, with HP20 it was six tabs (p<0.05). Only 26.7% (HP35) and 16.7% (HP20) of the participants reported TS, and no statistical differences were detected among them. Both in-office bleaching gels showed similar TS intensity, but the 35% HP agent produced faster bleaching.
authors: Restorative Dentistry, Universidade Estadual de Ponta Grossa, Ponta Grossa, Brazil. reis_ale@hotmail.com
authors: A
authors: A
authors: Reis
authors: S
authors: S
authors: Kossatz
authors: G C
authors: GC
authors: Martins
authors: A D
authors: AD
authors: Loguercio
mesh_terms: D000328:Adult; D003116:Color; D003481:Cuspid / Q000187:drug effects / Q000473:pathology; D003807:Dentin Sensitivity / Q000145:classification*; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D005782:Gels; D006801:Humans; D006861:Hydrogen Peroxide / Q000008:administration & dosage*; D007180:Incisor / Q000187:drug effects / Q000473:pathology; D008297:Male; D014073:Tooth Bleaching / Q000379:methods*; D058205:Tooth Bleaching Agents / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D005782:Gels; D058205:Tooth Bleaching Agents; D006861:Hydrogen Peroxide