title: Synthesis of functionalized indolizidines through Pauson-Khand cycloaddition of 2-allylpyrrolidines.
abstract: A concise entry to functionalized indolizidine scaffolds through a domino 2-aza-Cope-[3 + 2] dipolar cycloaddition and Pauson-Khand [2 + 2 + 1] cyclization has been accomplished. The process was conducted under mild conditions to afford diverse indolizidine systems as single diastereomers in good overall yields.
authors: Department of Chemistry, The University of Vermont, 82 University Place, Burlington, Vermont 05405, USA.
authors: Michael P
authors: MP
authors: McCormack
authors: Stephen P
authors: SP
authors: Waters
mesh_terms: D061565:Cycloaddition Reaction; D054836:Indolizidines / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D054836:Indolizidines; D011759:Pyrrolidines