title: A case of Mayer-Rokitansky-Küster-Hauser syndrome presenting as Graves disease.
abstract: The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is a congenital disorder characterized by aplasia of the uterus and the upper part of the vagina in an XX individual with normal development of secondary sexual characteristics. Individuals with this syndrome may also present with renal and skeletal abnormalities. We report a case of a 16-year-old girl presenting with thyrotoxicosis and primary amenorrhea. After being diagnosed with Graves disease, this patient was placed on antithyroid medication. Although her thyroid function normalized, she did not start to menstruate. Therefore, we assessed her primary amenorrhea and diagnosed the patient with MRKH syndrome through pelvic imaging. To our knowledge, an association between Graves disease and MRKH syndrome has not yet been reported.
authors: Department of Internal Medincine, The Catholic University of Korea, Seoul, South Korea.
authors: Ye-Jee
authors: YJ
authors: Lim
authors: Tae-Seo
authors: TS
authors: Sohn
authors: Seung-Hun
authors: SH
authors: Kang
authors: Kyung-Yoon
authors: KY
authors: Chang
authors: Bo-Kyung
authors: BK
authors: Kim
authors: Yeon-Ji
authors: YJ
authors: Kim
authors: Won-Chul
authors: WC
authors: Ha
authors: Su-Jin
authors: SJ
authors: Oh
authors: Hyun-Shik
authors: HS
authors: Son
mesh_terms: D058489:46, XX Disorders of Sex Development; D000015:Abnormalities, Multiple / Q000175:diagnosis*; D000293:Adolescent; D000568:Amenorrhea / Q000175:diagnosis*; D013956:Antithyroid Agents / Q000627:therapeutic use; D000013:Congenital Abnormalities; D003937:Diagnosis, Differential; D005260:Female; D006111:Graves Disease / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D007668:Kidney / Q000002:abnormalities; D008713:Methimazole / Q000627:therapeutic use; D009095:Mullerian Ducts / Q000002:abnormalities; D010388:Pelvis / Q000000981:diagnostic imaging; D019170:Somites / Q000002:abnormalities; D013131:Spine / Q000002:abnormalities; D013971:Thyrotoxicosis / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D014599:Uterus / Q000002:abnormalities; D014621:Vagina / Q000002:abnormalities
chemical_list: D013956:Antithyroid Agents; D008713:Methimazole