title: The health and structural consequences of acute knee injuries involving rupture of the anterior cruciate ligament.
abstract: Although there is an abundance of literature regarding the development of knee osteoarthritis after rupture of the anterior cruciate ligament (ACL), the mechanism underlying this link is not clear. Recent studies have reported that several factors may be predictive of the development of osteoarthritis, including damage to the menisci and articular cartilage during the initial trauma, altered knee biomechanics after injury, and episodic instability. This article summarizes recent developments in the understanding of the joint damage resulting from an ACL tear, and the influence that current and future treatment methods may have on the long-term progression to osteoarthritis.
authors: School of Medicine, University of Sydney, Sydney, New South Wales, Australia.
authors: Edward A
authors: EA
authors: Riordan
authors: Richard B
authors: RB
authors: Frobell
authors: Frank W
authors: FW
authors: Roemer
authors: David J
authors: DJ
authors: Hunter
mesh_terms: D016118:Anterior Cruciate Ligament / Q000473:pathology* / Q000503:physiopathology; D000070598:Anterior Cruciate Ligament Injuries; D001696:Biomechanical Phenomena; D002358:Cartilage, Articular / Q000293:injuries / Q000473:pathology / Q000503:physiopathology; D018450:Disease Progression; D006801:Humans; D007718:Knee Injuries / Q000150:complications* / Q000473:pathology* / Q000628:therapy; D020370:Osteoarthritis, Knee / Q000209:etiology* / Q000517:prevention & control; D016059:Range of Motion, Articular; D012421:Rupture