title: [Developmental dysphasia: assessment of the drug treatment efficacy].
abstract: To assess the efficacy of treatment with encephabol, we examined 40 children, aged from 3 to 5 years, with developmental dysphasia. All patients were randomized into two equal groups: group 1 received encephabol (suspension form, daily dosage 200-250 mg, or 12-15 mg/kg) during 2 months; group 2 did not receive this medication. In the first group, there was a significant improvement of expressive and impressive speech and speech attention; the active vocabulary and a number of phrases in colloquial speech increased by a factor of 3 versus 1.5 in the control group. After the treatment with encephabol, the parents reported the decrease in motor disturbances, psychosomatic disorders, the improvement of attention and the emotional state of the children.
authors: N N
authors: NN
authors: Zavadenko
authors: E V
authors: EV
authors: Kozlova
authors: I E
authors: IE
authors: Koltunov
mesh_terms: D001037:Aphasia / Q000188:drug therapy*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007804:Language Development; D007805:Language Development Disorders / Q000188:drug therapy*; D008297:Male; D011746:Pyrithioxin / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D011746:Pyrithioxin