title: The ultra-high risk concept-a review.
abstract: Attempts to identify people at imminent risk of psychotic disorder have been made during the past 20 years. High-risk criteria have been developed, and despite findings of a recent decline in the rate of onset of psychosis associated with these criteria, people identified still have a significantly greater risk, compared with the general population. Intervention studies in this group indicate that psychological treatments and fish oil appear to be just as effective as antipsychotics. Future research should refine risk factors for psychosis and examine outcomes other than psychosis. Research is also needed into what harms and benefits are associated with making the high-risk criteria into a formal diagnosis.
authors: Orygen Youth Health Research Centre, Centre for Youth Mental Health, The University of Melbourne, Melbourne, Australia. alison.yung@manchester.ac.uk
authors: Alison R
authors: AR
authors: Yung
authors: Barnaby
authors: B
authors: Nelson
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D015928:Cognitive Behavioral Therapy; D003131:Combined Modality Therapy / Q000379:methods; D005395:Fish Oils / Q000627:therapeutic use; D020022:Genetic Predisposition to Disease / Q000235:genetics; D006801:Humans; D062706:Prodromal Symptoms; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000235:genetics / Q000517:prevention & control / Q000523:psychology*; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment; D012307:Risk Factors; D012917:Social Adjustment; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D005395:Fish Oils