title: Fatal poisoning by isoniazid and rifampicin.
abstract: Isoniazid and rifampicin are used for management of tuberculosis. Acute poisoning due to isoniazid overdose is associated with repetitive generalized tonic-clonic seizures and severe metabolic acidosis. In toxic doses, rifampicin is known to produce hepatic, renal, hematological disorders, and convulsions. Sometimes, it may produce red man syndrome. We report a case of fatal poisoning with isoniazid and rifampicin. The case was characterized by late presentation, lactic acidosis, and renal failure.
authors: Department of Nephrology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
authors: A
authors: A
authors: Sridhar
authors: Y
authors: Y
authors: Sandeep
authors: C
authors: C
authors: Krishnakishore
authors: P
authors: P
authors: Sriramnaveen
authors: Y
authors: Y
authors: Manjusha
authors: V
authors: V
authors: Sivakumar
keywords: Fatal poisoning; isoniazid; rifampicin