title: Rewriting the bacterial glycocalyx via Suzuki-Miyaura cross-coupling.
abstract: Suzuki-Miyaura cross-coupling has been used to couple novel carbohydrate-based boronic acids, site-selectively, to the surface of E. coli at an unnatural amino acid. In this way, benign metal-catalyzed cellular switching allowed modulation of interactions with biomolecular partners via prokaryotic O-glycosylation mimics.
authors: Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.
authors: Christopher D
authors: CD
authors: Spicer
authors: Benjamin G
authors: BG
authors: Davis
mesh_terms: D000596:Amino Acids / Q000378:metabolism*; D001897:Boronic Acids / Q000737:chemistry*; D002241:Carbohydrates / Q000737:chemistry*; D002384:Catalysis; D004926:Escherichia coli / Q000378:metabolism*; D019276:Glycocalyx / Q000737:chemistry* / Q000378:metabolism; D006031:Glycosylation; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D000596:Amino Acids; D001897:Boronic Acids; D002241:Carbohydrates; D010165:Palladium