title: Association between movement and Sin Nombre virus (Bunyaviridae: Hantavirus) infection in North American deermice (Peromyscus maniculatus) in Colorado.
abstract: Capture data from long-term, mark-recapture studies were used to evaluate movements of North American deermice (Peromyscus maniculatus) on mark-recapture webs in Colorado with respect to Sin Nombre virus (SNV) infection status, age, sex, and trapping site. Latitude and longitude coordinates for each capture during the approximately 12-yr study were used to produce an individual minimum convex polygon (MCP) area representing the movements (not home range) of an individual mouse over time. These MCP areas were compared by SNV infection status (as determined by the presence of antibody), age, and sex. Antibody-negative deermice had significantly larger mean MCP areas than did antibody-positive mice. No differences in MCP area were found between male and female mice (either positive or negative). The smaller MCP areas of antibody-positive mice correspond to decreased movement by SNV-infected deermice on the trapping webs. These findings may indicate that SNV has a negative effect on movement, perhaps by reducing the health of infected deermice.
authors: Viral Special Pathogens Branch, Division of High Consequence Pathogens and Pathogenesis, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. bamman@cdc.gov
authors: Brian R
authors: BR
authors: Amman
authors: Arie P
authors: AP
authors: Manangan
authors: Timothy D
authors: TD
authors: Flietstra
authors: Charles H
authors: CH
authors: Calisher
authors: Darin S
authors: DS
authors: Carroll
authors: Kent D
authors: KD
authors: Wagoner
authors: James N
authors: JN
authors: Mills
mesh_terms: D000367:Age Factors; D025041:Animal Migration; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D003120:Colorado / Q000453:epidemiology; D005260:Female; D018804:Hantavirus Pulmonary Syndrome / Q000453:epidemiology / Q000662:veterinary*; D008297:Male; D010542:Peromyscus / Q000821:virology*; D012376:Rodent Diseases / Q000453:epidemiology*; D018571:Sentinel Surveillance / Q000662:veterinary; D016036:Seroepidemiologic Studies; D012737:Sex Factors; D029261:Sin Nombre virus / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral