title: Strain and strain rate echocardiography findings in children with asymptomatic congenital aortic stenosis.
abstract: The aim of our study was to evaluate myocardial functions with strain/strain rate echocardiography in asymptomatic patients having congenital aortic stenosis (CAS) with normal cardiac functions as determined by conventional echocardiographic techniques and comparing them with those of healthy controls. A total of 58 patients with various degrees of isolated CAS and 52 healthy controls were enrolled in this study. Conventional and two-dimensional speckle tracking (2DSTE) echocardiography were performed. Global longitudinal strain (LS) (-23.1 ± 3.6 and -23.8 ± 4.7), and longitudinal strain rate (LSR) (-1.49 ± 0.32 and -1.76 ± 0.39) values were lower, whereas circumferential strain (CS) (-25.9 ± 4.7 and -22.8 ± 6.4) and circumferential strain rate (CSR) (-1.82 ± 0.46 and -1.69 ± 0.49) values were greater in the patient group than in the control subjects. The difference was significant for global LSR and CS (p < 0.05) values. Regional analysis showed lower LS values in the basal part of the left-ventricular (LV) free wall and lower LSR values in the basal parts of both of the septum and free wall in the patient group (p < 0.05). CS values in the anteroseptal, posterior, and inferior walls were significantly greater in the patients (p < 0.05). 2DSTE detects subtle alterations in myocardial function in asymptomatic children with CAS. Impairment of LV long-axis function occurred earlier and was more prominent in basal parts of the interventricular septum and the free wall of the left ventricle.
authors: Department of Pediatric Cardiology, Faculty of Medicine, Gaziosmanpaşa University, Tokat, Turkey. vdogan86@yahoo.com
authors: Vehbi
authors: V
authors: Dogan
authors: Burhan
authors: B
authors: Öcal
authors: Utku Arman
authors: UA
authors: Orun
authors: Senem
authors: S
authors: Ozgur
authors: Osman
authors: O
authors: Yılmaz
authors: Mahmut
authors: M
authors: Keskin
authors: Ozben
authors: O
authors: Ceylan
authors: Selmin
authors: S
authors: Karademir
authors: Filiz
authors: F
authors: Şenocak
mesh_terms: D000886:Anthropometry; D001024:Aortic Valve Stenosis / Q000151:congenital* / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D016022:Case-Control Studies; D002648:Child; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male