title: Predictive value of elevated neutrophil to lymphocyte ratio in patients undergoing primary angioplasty for ST-segment elevation myocardial infarction.
abstract: OBJECTIVE
  The neutrophil to lymphocyte ratio (NLR) has been investigated as a new predictor for cardiovascular risk. Admission NLR would be predictive of adverse outcomes after primary angioplasty for ST-segment elevation myocardial infarction (STEMI).
  
  
  METHODS
  A total of 2410 patients with STEMI undergoing primary angioplasty were retrospectively enrolled. The study population was divided into tertiles based on the NLR values. A high NLR (n = 803) was defined as a value in the third tertile (>6.97), and a low NLR (n = 1607) was defined as a value in the lower 2 tertiles (≤6.97).
  
  
  RESULTS
  High NLR group had higher incidence of inhospital and long-term cardiovascular mortality (5% vs 1.4%, P < .001; 7% vs 4.8%, P = .02, respectively). High NLR (>6.97) was found as an independent predictor of inhospital cardiovascular mortality (odds ratio: 2.8, 95% confidence interval: 1.37-5.74, P = .005).
  
  
  CONCLUSIONS
  High NLR level is associated with increased inhospital and long-term cardiovascular mortality in patients with STEMI undergoing primary angioplasty.
authors: 1Department of Cardiology, Bezmialem Vakıf University, School of Medicine, Istanbul, Turkey.
authors: Mehmet
authors: M
authors: Ergelen
authors: Huseyin
authors: H
authors: Uyarel
authors: Servet
authors: S
authors: Altay
authors: Şeref
authors: Ş
authors: Kul
authors: Erkan
authors: E
authors: Ayhan
authors: Turgay
authors: T
authors: Isık
authors: Tuba
authors: T
authors: Kemaloğlu
authors: Mehmet
authors: M
authors: Gül
authors: Osman
authors: O
authors: Sönmez
authors: Ercan
authors: E
authors: Erdoğan
authors: Murat
authors: M
authors: Turfan
mesh_terms: D017130:Angioplasty / Q000379:methods*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000628:therapy*; D009504:Neutrophils / Q000473:pathology*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012307:Risk Factors
keywords: ST-segment elevation myocardial infarction; lymphocytes; neutrophils; primary angioplasty