title: [Primary retroperitoneal diffuse large B cell lymphoma with sclerosis mimicking idiopathic retroperitoneal fibrosis].
abstract: A 81-year-old man with a history of gastrointestinal stromal tumor (GIST) was admitted to our hospital due to increased level of LDH, and further testing revealed a serum sIL-2R level of 15,489 U/ml. CT scan demonstrated retroperitoneal fibrosis without lymphadenopathy, and bilateral hydronephrosis. He died of aspiration pneumonia, and post-mortem biopsy revealed diffuse infiltration of medium to large-sized lymphoid cells positive for CD20, CD79a, and BCL2 in the retroperitoneal space with mild fibrosis. These findings suggested a diagnosis of primary retroperitoneal diffuse large B-cell lymphoma (PRLBCL). PRLBCL is extremely rare, and should be included in the differential diagnosis in cases of retroperitoneal fibrosis.
authors: Department of Hematology, Kyoto Social Insurance Hospital, Japan.
authors: Mayumi
authors: M
authors: Hatsuse
authors: Shin-ichi
authors: S
authors: Fuchida
authors: Akira
authors: A
authors: Okano
authors: Satoshi
authors: S
authors: Murakami
authors: Harue
authors: H
authors: Haruyama
authors: Chihiro
authors: C
authors: Shimazaki
mesh_terms: D000369:Aged, 80 and over; D001344:Autopsy / Q000379:methods; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D012185:Retroperitoneal Fibrosis / Q000175:diagnosis / Q000473:pathology*; D012187:Retroperitoneal Space / Q000473:pathology*; D012598:Sclerosis / Q000175:diagnosis / Q000473:pathology*