title: Relation of excess body weight and survival in patients with esophageal adenocarcinoma: a meta-analysis.
abstract: Excess body weight (body mass index >25 kg/m(2)) is common in patients with esophageal adenocarcinoma. In this study, a meta-analysis was performed by searching PubMed, Cochrane Library, EMBASE, and Science Direct databases from 1960 to June 2012. Data were extracted from studies comparing survival in obese (body mass index >30), overweight (body mass index 25-29), and normal-weight (body mass index 20-24) patients undergoing esophagectomy. A total of six studies with 1988 cases were suitable for this global meta-analysis. Compared with patients of normal weight, the hazard ratio of postoperational survival for overweight and obese patients was 0.79 (95% confidence interval 0.65-0.95, P = 0.108) and 0.80 (95% confidence interval 0.68-0.93, P = 1.00), respectably. Taken together, the excess body weight did not have the value of predicting survival for patients with esophageal adenocarcinoma.
authors: Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China. hongliu180@126.com
authors: L
authors: L
authors: Hong
authors: H
authors: H
authors: Zhang
authors: Q
authors: Q
authors: Zhao
authors: Y
authors: Y
authors: Han
authors: J
authors: J
authors: Yang
authors: L
authors: L
authors: Brain
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D015992:Body Mass Index; D001835:Body Weight / Q000502:physiology*; D004938:Esophageal Neoplasms / Q000601:surgery*; D016629:Esophagectomy / Q000706:statistics & numerical data*; D005544:Forecasting; D006801:Humans; D009765:Obesity / Q000150:complications; D050177:Overweight / Q000150:complications; D016016:Proportional Hazards Models; D015996:Survival Rate; D016896:Treatment Outcome
keywords: body mass index; esophageal adenocarcinoma; survival