title: Cytomegalovirus: a probable cause of steroid-refractory ulcerative colitis.
abstract: Cytomegalovirus, regarded as a trigger of several autoimmune diseases, is an opportunistic pathogen. Patients with ulcerative colitis (UC) undergoing steroid treatment are susceptible to this infection. In the presence of cytomegalovirus, inflammation becomes more complex. Patients with active UC who are infected with cytomegalovirus are usually non-responders to steroid, while antiviral drugs could induce remission. Cytomegalovirus should be suggested as a probable cause of steroid-refractory UC based on the clinical data in the literatures.
authors: Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.
authors: Meng
authors: M
authors: Xue
authors: Shu Jie
authors: SJ
authors: Chen
authors: Liang Jing
authors: LJ
authors: Wang
authors: Ying
authors: Y
authors: Du
authors: Jian Min
authors: JM
authors: Si
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000188:drug therapy / Q000601:surgery / Q000821:virology*; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy; D004351:Drug Resistance; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D005938:Glucocorticoids