title: Hypomanic episode as a first presentation of a large B-cell lymphoma.
abstract: This case report describes a cachectic patient with a first hypomanic episode, hypercortisolism and a newly diagnosed large B-cell lymphoma. Hypercortisolism, causing the manic symptoms, may be explained due to low leptin levels as a result of cancer cachexia and fasting. Patients with cancer frequently have psychiatric complications, but manic symptoms are rare. To our knowledge, this is the first report of a patient with a lymphoma presenting with manic symptoms without any cerebral abnormalities.
authors: Department of Internal Medicine, University Hospital Maastricht, Maastricht, The Netherlands. r.oldeengberink@student.maastrichtuniversity.nl
authors: Rik H G
authors: RH
authors: Olde Engberink
authors: Marion C J
authors: MC
authors: Knippels
authors: Evelien
authors: E
authors: Pijpers
mesh_terms: D000368:Aged; D001024:Aortic Valve Stenosis / Q000150:complications; D001714:Bipolar Disorder / Q000150:complications*; D002100:Cachexia / Q000150:complications; D003480:Cushing Syndrome / Q000150:complications; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000175:diagnosis