title: Neurotoxic effects of nonylphenol: a review.
abstract: Nonylphenol (NP), identified as an environmental endocrine disruptor, used as important raw materials for detergents, emulsifiers, and wetting agents in industry and is also found in paints, pesticides, and household toiletries. NP has been reported to have deleterious effects on central nervous system (CNS) other than reproductive and immune systems including disrupting neuroendocrine homeostasis, altering cognitive function, and neurotoxicity of tissues, etc., particularly when NP's disruption occurs during critical developmental window of brain. This review will discuss the evidence for environmental endocrine disruption of NP and the sequelae on endocrine, reproductive and nerve functions, as well as causal relationships between endocrine disruption and cognitive behavior effects.
authors: School of Public Health, Zunyi Medical College, 563003 Zunyi, Guizhou, P.R. China. Xujie360@sina.com
authors: Xu
authors: X
authors: Jie
authors: Li
authors: L
authors: Jianmei
authors: Feng
authors: F
authors: Zheng
authors: Gong
authors: G
authors: Lei
authors: Zhang
authors: Z
authors: Biao
authors: Yu
authors: Y
authors: Jie
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism*; D001927:Brain Diseases / Q000139:chemically induced* / Q000503:physiopathology*; D052244:Endocrine Disruptors / Q000506:poisoning; D006801:Humans; D020258:Neurotoxicity Syndromes / Q000209:etiology* / Q000503:physiopathology*; D010636:Phenols / Q000506:poisoning*
chemical_list: D052244:Endocrine Disruptors; D010636:Phenols; C025256:nonylphenol