title: Subclinical hypothyroidism after vascular complicated pregnancy.
abstract: OBJECTIVE
  Women with a history of vascular complicated pregnancy are at risk for developing remote cardiovascular disease. It is associated with underlying cardiovascular risk factors both jeopardizing trophoblast and vascular function. Subclinical hypothyroidism may relate to both conditions.
  
  
  METHODS
  In 372 women with a history of vascular complicated pregnancy, we assessed thyroid function.
  
  
  RESULTS
  Subclinical hypothyroidism was diagnosed in 73/372 women (19.6%). It occurred more often when pregnancy ended before 32 weeks of gestation (p = 0.008).
  
  
  CONCLUSIONS
  In this cohort, subclinical hypothyroidism is more common after very preterm delivery. It may contribute to the elevated risk of remote cardiovascular disease.
authors: Department of Obstetrics and Gynaecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. M.vanderzanden@obgyn.umcn.nl
authors: Moniek
authors: M
authors: van der Zanden
authors: Rianne J
authors: RJ
authors: Hop-de Groot
authors: Fred C G J
authors: FC
authors: Sweep
authors: H Alec
authors: HA
authors: Ross
authors: Martin
authors: M
authors: den Heijer
authors: Marc E A
authors: ME
authors: Spaanderman
mesh_terms: D000037:Abruptio Placentae / Q000097:blood / Q000453:epidemiology; D000328:Adult; D005260:Female; D005317:Fetal Growth Retardation / Q000097:blood / Q000453:epidemiology*; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000097:blood / Q000453:epidemiology*; D007037:Hypothyroidism / Q000097:blood / Q000453:epidemiology* / Q000209:etiology; D008055:Lipids / Q000097:blood; D009426:Netherlands / Q000453:epidemiology; D011247:Pregnancy; D015995:Prevalence; D013960:Thyroid Function Tests
chemical_list: D008055:Lipids