title: [Primary cardiac neoplasms: a clinicopathologic analysis of 81 cases].
abstract: OBJECTIVE
  To study the disease spectrum, clinical and pathologic features of primary cardiac neoplasms at a single medical institution during a period of eight years.
  
  
  METHODS
  The clinical and pathologic features of 81 cases of primary cardiac neoplasms encountered at the Affiliated Hospital of Medical College, Qingdao University from January, 2004 to December, 2011, either for cardiovascular surgery or as pathology consultation cases, were retrospectively reviewed. Immunohistochemical study was carried out in selected examples.
  
  
  RESULTS
  Amongst the 81 cases studied, 73 cases (90.1%) were benign and 8 cases (9.9%) were malignant. Cardiac myxomas accounted for 97.3% (71/73) of all the benign cases. Six of the 8 malignant cases represented soft tissue sarcomas. The commonest presenting symptom was dyspnea. The histologic subtypes included myxoma (number = 71), angiosarcoma (number = 2), malignant fibrous histiocytoma (number = 2), hemangioma (number = 1), liposarcoma (number = 1), lymphoma (number = 1), myxofibrosarcoma (number = 1) and papillary fibroelastoma (number = 1).
  
  
  CONCLUSIONS
  While the majority of primary cardiac neoplasms are myxomas, other tumor types do exist. Accurate histologic diagnosis and timely surgery are crucial in patient management.
authors: Department of Pathology, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China. qdwangjigang@hotmail.com
authors: Ji-gang
authors: JG
authors: Wang
authors: Hui
authors: H
authors: Liu
authors: Wen-juan
authors: WJ
authors: Yu
authors: Yu-jun
authors: YJ
authors: Li
authors: Fang-jie
authors: FJ
authors: Xin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D005350:Fibroma / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D005354:Fibrosarcoma / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D006338:Heart Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D006391:Hemangioma / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D006394:Hemangiosarcoma / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D051677:Histiocytoma, Malignant Fibrous / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008080:Liposarcoma / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D008223:Lymphoma / Q000378:metabolism / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009232:Myxoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D012509:Sarcoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome; D014746:Vimentin / Q000378:metabolism; D055815:Young Adult
chemical_list: D014746:Vimentin