title: Incidence of adverse outcomes associated with gestational diabetes mellitus in low- and middle-income countries.
abstract: BACKGROUND
  The contribution of medical conditions such as diabetes mellitus to maternal and neonatal ill-health in low- and middle-income countries is not well documented.
  
  
  OBJECTIVE
  To ascertain the incidence of adverse outcomes associated with gestational diabetes mellitus (GDM) in these countries.
  
  
  METHODS
  Electronic databases were searched between 1990 and 2011.
  
  
  METHODS
  Observational, experimental, and quasi-experimental studies reporting adverse outcomes associated with GDM in mothers and their infants in low- and middle-income countries were included.
  
  
  METHODS
  Titles and abstracts were screened, and full-text articles were independently assessed by at least 2 reviewers. Characteristics of studies were tabulated and quality assessment performed. Median and interquartile range (IQR) were computed for each adverse outcome.
  
  
  RESULTS
  25 articles were included from an initial 1282 citations. High median incidences of cesarean (43.8%; IQR, 34.9%-65.9%), neonatal jaundice (17.1%; IQR, 8.5%-22.9%), and macrosomia (17.0%; IQR, 8.3%-32.5%) were reported in women with GDM.
  
  
  CONCLUSIONS
  The high incidence of some complications of GDM is a concern and may indicate poorer care for women with GDM in low-resource settings. The wide IQRs found indicate uncertainty about the burden of GDM in these settings.
authors: Immpact, University of Aberdeen, Aberdeen, UK.
authors: Zheng
authors: Z
authors: Wang
authors: Lovney
authors: L
authors: Kanguru
authors: Julia
authors: J
authors: Hussein
authors: Ann
authors: A
authors: Fitzmaurice
authors: Katherine
authors: K
authors: Ritchie
mesh_terms: D002585:Cesarean Section / Q000706:statistics & numerical data; D003906:Developing Countries; D016640:Diabetes, Gestational / Q000503:physiopathology*; D005260:Female; D005320:Fetal Macrosomia / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000453:epidemiology / Q000209:etiology; D011247:Pregnancy; D011256:Pregnancy Outcome