title: A tutorial on the application of ion-selective electrode potentiometry: an analytical method with unique qualities, unexplored opportunities and potential pitfalls; tutorial.
abstract: Ion-selective potentiometry enjoys practical utility as a simple analytical technique to measure ionic constituents in complex samples. Advances in the field have improved the selectivity and decreased the detection limit of ion-selective electrodes (ISEs) by orders of magnitude such that trace analysis in micro and nanomolar concentrations is now possible with potentiometric sensors. This tutorial reviews the fundamental principles of ion-selective potentiometry, describes the practical considerations involved in the use of these sensors to measure real samples, and discusses the statistical evaluation of experimental results compared with alternative analytical techniques.
authors: Department of Biomedical Engineering, The University of Memphis, Memphis, TN 38152, United States. elindner@memphis.edu
authors: Ernő
authors: E
authors: Lindner
authors: Bradford D
authors: BD
authors: Pendley
mesh_terms: D004553:Electric Conductivity; D004566:Electrodes; D011199:Potentiometry / Q000295:instrumentation / Q000379:methods*