title: Association of arterial stiffness with obesity in Australian women: a pilot study.
abstract: This study investigated the arterial stiffness status in overweight/obese Australian women compared with their lean counterparts. Twenty-six Caucasian women were designated into one of two groups: overweight/obese (body mass index [BMI] 25-34.9 kg/m2 [ n=12]) and lean (BMI 18.5-24.9 kg/m2 [n=14]) groups. Participants were assessed for clinical, anthropometric, metabolic, and augmentation index (AIx) measurements. Age was similar between groups (P=.482). BMI was significantly higher in overweight/obese compared with lean participants (30.26±1.09 vs 21.62±0.52 kg/m2, P=.001) as well as the percentage of body fat (40.60±2.43 vs 21.57±1.13, P=.001), waist circumference (91.47±2.77 vs 70.67±1.60, P=.001), and waist/hip ratio (0.81±0.04 vs 0.71±0.03, P=.036). Overweight/obese group showed higher total cholesterol, triglyceride, low-density lipoprotein cholesterol, and fasting glucose levels compared with the lean group (all P<.05). Both systolic (122.92±3.18 mm Hg vs 108.14±2.42 mm Hg, P=.001) and diastolic (83.58±2.43 mm Hg vs 72.43±1.29 mm Hg, P=.0001) blood pressures, as well as AIx (50.08±4.7 vs 120.79±2.17, P=.001) were significantly higher in the overweight/obese group compared with the lean group. AIx was positively associated with measurements of body composition (P<.05), triglycerides (r=0.361, P=.035) and glucose levels (r=0.371, P=.031), and systolic and diastolic blood pressure (r=0.793 and r=0.718, respectively; P=.0001). This data suggests that arterial stiffness is associated with obesity, along with other metabolic abnormalities in Australian women.
authors: School of Public Health, Curtin Health Innovation Research Institute, Curtin University, Perth, WA, Australia. s.pal@curtin.edu.au
authors: Sebely
authors: S
authors: Pal
authors: Simone
authors: S
authors: Radavelli-Bagatini
mesh_terms: D000328:Adult; D001315:Australia; D001794:Blood Pressure / Q000502:physiology; D001823:Body Composition; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D009765:Obesity / Q000453:epidemiology / Q000208:ethnology* / Q000503:physiopathology*; D050177:Overweight / Q000453:epidemiology / Q000208:ethnology* / Q000503:physiopathology*; D010865:Pilot Projects; D013851:Thinness / Q000453:epidemiology / Q000208:ethnology / Q000503:physiopathology; D059289:Vascular Stiffness / Q000502:physiology*; D055105:Waist Circumference / Q000502:physiology; D049629:Waist-Hip Ratio; D044465:White People
chemical_list: D008055:Lipids