title: Two cases of meningococcal purpura fulminans: the 'less is more' approach.
abstract: This study presents a case series of patients with meningococcal purpura fulminans who were treated at a tertiary referral centre within a few days of each other. Presenting with signs and symptoms of florid meningococcal sepsis, they were managed initially by physicians and intensivists, whereas the development of large purpuric areas and tissue necrosis was managed expectantly by plastic surgeons. When the patients were deemed to have recovered clinically and the necrosis delineated, surgical management was implemented with subsequent involvement of various rehabilitation services. This article highlights the cases of two patients, and their clinical presentation, management and rehabilitation together with a current literature review on this area.
authors: Department of Plastic and Reconstructive Surgery, University Hospitals of Coventry and Warwickshire, Coventry, Warwickshire, UK.
authors: Zeeshan
authors: Z
authors: Ahmad
authors: Robert
authors: R
authors: Jordan
authors: Rana
authors: R
authors: Das-Gupta
authors: Shekhar
authors: S
authors: Srivastava
mesh_terms: D000328:Adult; D003646:Debridement; D006801:Humans; D008297:Male; D008589:Meningococcal Infections / Q000150:complications / Q000473:pathology* / Q000628:therapy*; D055665:Purpura Fulminans / Q000382:microbiology / Q000473:pathology* / Q000601:surgery*; D016038:Skin Transplantation; D055815:Young Adult
keywords: Burns wound model; Debridement; Meningococcal sepsis; Multidisciplinary approach; Plastic surgery; Problem solving; Reconstruction; Tissue perfusion