title: Solvent-free synthesis of α-amino nitrile-derived ureas.
abstract: An efficient and environmentally friendly methodology for the solvent-free synthesis of α-amino nitrile derived ureas from α-amino acid based amino nitriles has been developed. At room temperature no epimerization was observed in the resulting ureas, but under microwave heating, epimerization occurred at the chiral center bearing the cyano group.
authors: Instituto de Química Médica (CSIC), Juan de la Cierva 3, 28006 Madrid, Spain.
authors: Pilar
authors: P
authors: Ventosa-Andrés
authors: Juan A
authors: JA
authors: González-Vera
authors: M Teresa
authors: MT
authors: García-López
authors: Rosario
authors: R
authors: Herranz