title: Bone metastases from prostate cancer: 18F-fluoride PET/CT in a patient with discordant bone scintigraphy and 11C-choline PET/CT.
abstract: Bone scintigraphy has been used extensively in prostate cancer patients to detect bone involvement. (11)C-choline PET/CT is indicated when a biochemical recurrence is suspected, as this procedure is able to detect local recurrence, lymph-node infiltration, and metastases.In cases where the results of these 2 procedures do not coincide, MRI is then usually performed. (18)F-fluoride may become an alternative to MRI for bone imaging.In our patient series, all bone lesions with (11)C-choline uptake were metastases. (18)F-Fluoride did not increase specificity of (11)C-choline but increased sensitivity of bone scintigraphy. CT helped in the interpretation of osteoarthritis and trauma lesions.
authors: Unidad PET/TC CETIR-ERESA, 08950 Esplugues de Llobregat, Barcelona, Spain. jrgarcia@cetir.es
authors: Garzon
authors: G
authors: Garcia
authors: Eduard
authors: E
authors: Riera
authors: Eulalia
authors: E
authors: Valls
authors: Marina
authors: M
authors: Soler
authors: Pere
authors: P
authors: Bassa
authors: Merce
authors: M
authors: Moragas
authors: Francisco
authors: F
authors: Lomeña
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology / Q000556:secondary*; D002250:Carbon Radioisotopes; D002794:Choline; D005459:Fluorides; D005462:Fluorine Radioisotopes; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D011471:Prostatic Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D002250:Carbon Radioisotopes; D005462:Fluorine Radioisotopes; D002794:Choline; D005459:Fluorides