title: Expression of antiangiogenic factors in the placental structures in pre-eclampsia.
abstract: Comparative morphological study of the placentas was carried out in women with pregnancy aggravated by the development of pre-eclampsia. Immunohistochemical methods showed increased expression of endoglin (CD105) and VEGFR1 in all placental structures. The intensity of endoglin and VEGFR1 expression was maximum in the syncytiotrophoblast and extravillous cytotrophoblast cells in severe pre-eclampsia.
authors: V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, the Ministry of Health and Social Development of the Russian Federation, Moscow, Russia. ashegolev@oparina4.ru
authors: A I
authors: AI
authors: Shchyogolev
authors: E A
authors: EA
authors: Dubova
authors: K A
authors: KA
authors: Pavlova
authors: V M
authors: VM
authors: Lyapin
authors: G T
authors: GT
authors: Sukhikh
mesh_terms: D000328:Adult; D015703:Antigens, CD / Q000378:metabolism*; D000071063:Endoglin; D005260:Female; D006801:Humans; D010920:Placenta / Q000378:metabolism*; D011225:Pre-Eclampsia / Q000378:metabolism*; D011247:Pregnancy; D011956:Receptors, Cell Surface / Q000378:metabolism*; D014327:Trophoblasts / Q000378:metabolism; D040281:Vascular Endothelial Growth Factor Receptor-1 / Q000378:metabolism*
chemical_list: D015703:Antigens, CD; C064206:ENG protein, human; D000071063:Endoglin; D011956:Receptors, Cell Surface; D040281:Vascular Endothelial Growth Factor Receptor-1