title: Graphene oxide coated capillary for chiral separation by CE.
abstract: This article describes a new application of graphene oxide (GO) in CE based on the coating of fused silica capillary for chiral separation. The coated capillary was characterized by SEM, energy dispersive X-ray spectroscopy, and Raman spectra. The results indicated that the capillary was coated with GO. Chiral separations were carried out in the GO-coated capillary for the ephedrine-pseudoephedrine (E-PE) isomers and β-methylphenethylamine (β-Me-PEA) isomers at the optimal buffer conditions without any chiral selector by CE. The precision and reproducibility of GO-coated capillary were investigated, and the RSDs of migration time (n = 6) for the E-PE isomers were 1.35-1.41%, and 0.97-3.50% for β-Me-PEA isomers, respectively. The LOD for E-PE isomers and β-Me-PEA isomers was 3 μM and 18 μM, respectively.
authors: Department of Chemistry, Capital Normal University, Beijing, China. yensh@cnu.edu.cn
authors: Nengsheng
authors: N
authors: Ye
authors: Jian
authors: J
authors: Li
authors: Yali
authors: Y
authors: Xie
authors: Chang
authors: C
authors: Liu
mesh_terms: D000613:Aminobutyrates / Q000032:analysis* / Q000737:chemistry; D019075:Electrophoresis, Capillary / Q000295:instrumentation / Q000379:methods*; D029789:Ephedra / Q000737:chemistry; D004809:Ephedrine / Q000032:analysis*; D006108:Graphite; D008855:Microscopy, Electron, Scanning; D010936:Plant Extracts / Q000032:analysis / Q000737:chemistry; D054199:Pseudoephedrine / Q000032:analysis*; D015203:Reproducibility of Results; D013052:Spectrometry, X-Ray Emission; D013059:Spectrum Analysis, Raman; D013237:Stereoisomerism
chemical_list: D000613:Aminobutyrates; D010936:Plant Extracts; C010535:2-amino-3-phenylbutanoic acid; D006108:Graphite; D054199:Pseudoephedrine; D004809:Ephedrine