title: [MRI for myocarditis].
abstract: Cardiovascular magnetic resonance imaging (CMRI) has become the primary tool for the non-invasive assessment in patients with suspected myocarditis, especially after exclusion of acute coronary syndrome (ACS) for the differential diagnosis. Various MRI parameters are available which have different accuracies. Volumetric and functional ventricular assessment and the occurrence of pericardial effusion alone demonstrate only a poor sensitivity and specificity. The calculation of the T2-ratio (edema assessment), the early or global relative myocardial enhancement (gRE) and the late gadolinium enhancement (LGE), which represents irreversibly injured myocardium, are more specific parameters. All MRI parameters demonstrate the best accuracy in infarct-like acute myocarditis, whereas in chronic myocarditis sensitivity and specificity are less accurate. Therefore, a multisequential (at least two out of three parameters are positive) approach is recommended. The assessment of the value of newer, more quantitative MRI sequences, such as T1 and T2-mapping is still under investigation.
authors: Abteilung für Diagnostische und Interventionelle Radiologie, Herzzentrum, Universität Leipzig, Deutschland. matthias.gutberlet@herzzentrum-leipzig.de
authors: M
authors: M
authors: Gutberlet
authors: C
authors: C
authors: Lücke
authors: C
authors: C
authors: Krieghoff
authors: L
authors: L
authors: Hildebrand
authors: P
authors: P
authors: Lurz
authors: J
authors: J
authors: Steiner
authors: J
authors: J
authors: Adam
authors: I
authors: I
authors: Eitel
authors: H
authors: H
authors: Thiele
authors: M
authors: M
authors: Grothoff
authors: M
authors: M
authors: Grotthoff
authors: L
authors: L
authors: Lehmkuhl
mesh_terms: D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D009205:Myocarditis / Q000175:diagnosis*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013318:Stroke Volume