title: M-cholinoreactivity of erythrocytes of non-pregnant and pregnant women evaluated by changes in the rate of erythrocyte agglutination under the influence of acetylcholine.
abstract: Acetylcholine (5.5×10(-10)-5.5×10(-6)M) accelerated erythrocyte agglutination in men, non-pregnant women in follicular phase of the menstrual cycle, and pregnant women in the first trimester. The effect was blocked with atropine (5.5×10(-6)M). Acetylcholine had no effect on the rate of erythrocyte agglutination in non-pregnant women in the luteal phase and pregnant women in the second and third trimesters, which coincided with the development of myometrium refractoriness to acetylcholine in pregnant women. The results indicate that erythrocytes can reflect M-cholinoreactivity of internal organs.
authors: Kirov State Medical Academy; Vyatka State Humanities University, Russia.
authors: A I
authors: AI
authors: Strelnikova
authors: V I
authors: VI
authors: Tsirkin
authors: A V
authors: AV
authors: Krysova
authors: S V
authors: SV
authors: Hlybova
authors: S L
authors: SL
authors: Dmitrieva
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology*; D000293:Adolescent; D000328:Adult; D001285:Atropine / Q000494:pharmacology; D004912:Erythrocytes / Q000187:drug effects* / Q000378:metabolism*; D005260:Female; D006384:Hemagglutination / Q000187:drug effects*; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011976:Receptors, Muscarinic / Q000378:metabolism*; D055815:Young Adult
chemical_list: D011976:Receptors, Muscarinic; D001285:Atropine; D000109:Acetylcholine