title: [Calcium pyrophosphate dihydrate crystal deposition disease: a clinicopathologic analysis of 20 cases].
abstract: OBJECTIVE
  To investigate the clinicopathologic features of calcium pyrophosphate dihydrate crystal deposition disease (CPPD-CDD).
  
  
  METHODS
  The clinical and pathologic profiles were retrospectively analysed in 20 cases of CPPD-CDD.
  
  
  RESULTS
  CPPD-CDD was far more common in women, most frequently involving joints, especially the knees and presenting with various arthrisis. Abnormally calcified and the articular damages were characteristic features by imageing. Histologically, multifocal indigo granular calcinosis was seen in synovium and sometimes appeared as needle-shaped or rhomboid crystals, which characterized the CPPD.
  
  
  CONCLUSIONS
  Though clinical symptoms of CPPD are quite variable, the definite diagnosis can be made by the abnormal calcification and joint damage radiographically and the indigo CPPD crystals histopathologically.
authors: Department of Pathology, Foshan Hospital of Traditional Chinese Medicine, Foshan 528000, China. fhq039@yahoo.com.cn
authors: Hui-qiong
authors: HQ
authors: Fang
authors: Qi-ming
authors: QM
authors: Li
authors: Yao-qu
authors: YQ
authors: Huang
authors: Ji-si
authors: JS
authors: Xing
authors: Rong-jun
authors: RJ
authors: Mao
authors: Le
authors: L
authors: Xie
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002805:Chondrocalcinosis / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D006801:Humans; D007403:Intervertebral Disc / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D013583:Synovial Membrane / Q000473:pathology; D014057:Tomography, X-Ray Computed