title: Headache in hemifacial spasm patients.
abstract: OBJECTIVE
  To assess prevalence of headaches in patients with hemifacial spasm. To determine whether hemifacial spasm provokes headaches and identifies predictive factors. To evaluate whether botulinum toxin given for hemifacial spasm improves headaches.
  
  
  METHODS
  Seventy patients with hemifacial spasm were evaluated for headaches. The relationship of headaches with hemifacial spasm, impact on quality of life (HIT-6), and improvement in headaches from botulinum toxin was recorded. Data on duration, severity, and impact on quality of life (HFS-7) of hemifacial spasm were collected.
  
  
  RESULTS
  Hemifacial spasm-related headache was significantly associated with increased hemifacial spasm severity (P < 0.001) and HIT-6 (P = 0.024). Greater hemifacial spasm severity was predictive of hemifacial spasm-related headache (P = 0.006, OR 19.1, 95% CI 2.35-155.64). Botulinum toxin (BTX) for hemifacial spasm improved hemifacial spasm-related headaches (P < 0.001).
  
  
  CONCLUSIONS
  Hemifacial spasm can complicate headaches, particularly in patients with greater hemifacial spasm severity. Individually tailored regimens of botulinum toxin may be indicated in these patients.
authors: Department of Neurology, Singapore General Hospital, Singapore.
authors: T
authors: T
authors: Peeraully
authors: S-F
authors: SF
authors: Tan
authors: S M C
authors: SM
authors: Fook-Chong
authors: K M
authors: KM
authors: Prakash
authors: E-K
authors: EK
authors: Tan
mesh_terms: D000700:Analgesics / Q000627:therapeutic use; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use; D015331:Cohort Studies; D015897:Comorbidity; D005260:Female; D006261:Headache / Q000188:drug therapy / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology / Q000523:psychology; D019569:Hemifacial Spasm / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009465:Neuromuscular Agents / Q000627:therapeutic use; D015995:Prevalence; D011788:Quality of Life; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
chemical_list: D000700:Analgesics; D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A