title: Gait coordination in Parkinson disease: effects of step length and cadence manipulations.
abstract: BACKGROUND
  Gait impairments are well documented in those with PD. Prior studies suggest that gait impairments may be worse and ongoing in those with PD who demonstrate FOG compared to those with PD who do not.
  
  
  OBJECTIVE
  Our aim was to determine the effects of manipulating step length and cadence individually, and together, on gait coordination in those with PD who experience FOG, those with PD who do not experience FOG, healthy older adults, and healthy young adults.
  
  
  METHODS
  Eleven participants with PD and FOG, 16 with PD and no FOG, 18 healthy older, and 19 healthy young adults walked across a GAITRite walkway under four conditions: Natural, Fast (+50% of preferred cadence), Small (-50% of preferred step length), and SmallFast (+50% cadence and -50% step length). Coordination (i.e. phase coordination index) was measured for each participant during each condition and analyzed using mixed model repeated measure ANOVAs.
  
  
  RESULTS
  FOG was not elicited. Decreasing step length alone or decreasing step length and increasing cadence together affected coordination. Small steps combined with fast cadence resulted in poorer coordination in both groups with PD compared to healthy young adults and in those with PD and FOG compared to healthy older adults.
  
  
  CONCLUSIONS
  Coordination deficits can be identified in those with PD by having them walk with small steps combined with fast cadence. Short steps produced at high rate elicit worse coordination than short steps or fast steps alone.
authors: Program in Physical Therapy, Washington University in St Louis School of Medicine, St Louis, MO 63108, United States.
authors: April J
authors: AJ
authors: Williams
authors: Daniel S
authors: DS
authors: Peterson
authors: Gammon M
authors: GM
authors: Earhart
mesh_terms: D000328:Adult; D000368:Aged; D001259:Ataxia / Q000209:etiology / Q000503:physiopathology*; D016022:Case-Control Studies; D005260:Female; D005684:Gait / Q000502:physiology; D020233:Gait Disorders, Neurologic / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications / Q000503:physiopathology*; D055815:Young Adult
keywords: Coordination; F; FOG-Q; Female; Freezing of Gait Questionnaire; Freezing of gait; M; MDS-UPDRS-3; Male; Movement Disorder Society Unified Parkinson Disease Rating Scale Motor Subscale 3; Parkinson disease; Yrs; years