title: A case of secondary erythromelalgia with unusual histological findings.
abstract: Erythromelalgia clinically presents with episodic burning, erythema, and warmth of acral sites. It can be divided into primary and secondary associated with myeloproliferative and autoimmune conditions. Histology commonly shows capillary proliferation, swelling of endothelial cells, perivascular edema, and chronic inflammation with sparse lymphocytic infiltrate. We report a case of a 55-year-old man with classical secondary erythromelalgia clinically; however, he had unusual histological findings on biopsy comprising of acute perivascular infiltrate and perivascular mucin. This is the first report of such findings in the context of secondary erythromelalgia.
authors: Department of Dermatology, Salford Royal NHS Foundation Trust, Stott lane, Salford, United Kingdom. waseembakkour79@hotmail.com
authors: Waseem
authors: W
authors: Bakkour
authors: Luisa
authors: L
authors: Motta
authors: Elizabeth
authors: E
authors: Stewart
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D001706:Biopsy; D004916:Erythromelalgia / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011087:Polycythemia Vera / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D012867:Skin / Q000098:blood supply* / Q000187:drug effects / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001241:Aspirin