title: No benefit of glutamine supplementation on persistent diarrhea in Ugandan children.
abstract: We evaluated the efficacy of oral glutamine supplementation in children 2 to 60 months of age with persistent diarrhea by 1:1 randomization to standard treatment alone or together with twice daily glutamine. The failure rate was similar in both arms (relative risk: 1.8 [95% confidence interval: 0.8-3.7], P = 0.12). Glutamine supplementation showed no benefit on the outcome of persistent diarrhea.
authors: Department of Paediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda.
authors: Justine M
authors: JM
authors: Kamuchaki
authors: Sarah
authors: S
authors: Kiguli
authors: Eric
authors: E
authors: Wobudeya
authors: Robert
authors: R
authors: Bortolussi
mesh_terms: D002675:Child, Preschool; D003967:Diarrhea / Q000188:drug therapy* / Q000453:epidemiology; D019587:Dietary Supplements; D005973:Glutamine / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D018709:Statistics, Nonparametric; D016896:Treatment Outcome; D014454:Uganda / Q000453:epidemiology
chemical_list: D005973:Glutamine