title: B0 insensitive multiple-quantum resolved sodium imaging using a phase-rotation scheme.
abstract: Triple-quantum filtering has been suggested as a mechanism to differentiate signals from different physiological compartments. However, the filtering method is sensitive to static field inhomogeneities because different coherence pathways may interfere destructively. Previously suggested methods employed additional phase-cycles to separately acquire pathways. Whilst this removes the signal dropouts, it reduces the signal-to-noise per unit time. In this work we suggest the use of a phase-rotation scheme to simultaneously acquire all coherence pathways and then separate them via Fourier transform. Hence the method yields single-, double- and triple-quantum filtered images. The phase-rotation requires a minimum of 36 instead of six cycling steps. However, destructive interference is circumvented whilst maintaining full signal-to-noise efficiency for all coherences.
authors: Institute of Neuroscience and Medicine-4, Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.
authors: Daniel P
authors: DP
authors: Fiege
authors: Sandro
authors: S
authors: Romanzetti
authors: Desmond H Y
authors: DH
authors: Tse
authors: Daniel
authors: D
authors: Brenner
authors: Avdo
authors: A
authors: Celik
authors: Jörg
authors: J
authors: Felder
authors: N Jon
authors: NJ
authors: Shah
mesh_terms: D005583:Fourier Analysis; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation / Q000379:methods*; D015233:Models, Statistical; D019047:Phantoms, Imaging; D059629:Signal-To-Noise Ratio; D012964:Sodium / Q000737:chemistry*
chemical_list: D012964:Sodium