title: [Anti-inflammatory properties of antidepressants (a review of experimental results)].
abstract: The review presents comparative description of anti-inflammatory effects of antidepressants from various classes studied on carrageenan- and formalin-induced paw edema in rats. The role of the central and peripheral components in the mechanisms of anti-inflammatory activity and the drug effects on production of mediators and modulators of inflammation is discussed.
authors: V N
authors: VN
authors: Khaziakhmetova
authors: L E
authors: LE
authors: Ziganshina
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002351:Carrageenan; D016207:Cytokines / Q000097:blood / Q000276:immunology; D004334:Drug Administration Schedule; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy* / Q000276:immunology; D005557:Formaldehyde; D007249:Inflammation / Q000139:chemically induced / Q000188:drug therapy / Q000276:immunology; D051381:Rats
chemical_list: D000893:Anti-Inflammatory Agents; D000928:Antidepressive Agents; D016207:Cytokines; D005557:Formaldehyde; D002351:Carrageenan