title: Diagnostic pathway to amyotrophic lateral sclerosis (ALS): the significance of Babinski's sign in a unique patient and the necessity for a multidisciplinary approach.
abstract: In this case report, we present a patient with rare diagnosis of amyotrophic lateral sclerosis (ALS). In this patient, four different neurological disorders were diagnosed in a short-time period of 8 months. The first three diagnoses, chronic low back and leg pain, a left frontal gemistocytic astrocytoma WHO grade 2 and suspected Lyme's disease, could not fully explain the signs of physical examination. Finally, the diagnosis of ALS could reduce these signs to the same denominator.
authors: Department of Neurosurgery, Maastricht University Medical Center, Maastricht, The Netherlands. v.bulthuis@mumc.nl
authors: Vincent
authors: V
authors: Bulthuis
authors: Marielle
authors: M
authors: Vlooswijk
authors: Henk
authors: H
authors: van Santbrink
authors: Olaf
authors: O
authors: Schijns
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000150:complications / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D001405:Reflex, Babinski / Q000175:diagnosis / Q000209:etiology*