title: [Clinical and laboratory features of acute monocytic leukemia with B lymphoproliferative disorders].
abstract: OBJECTIVE
  To identify the clinical and pathological features of acute myeloid leukemia with B lymphoproliferative disorders.
  
  
  METHODS
  The characteristics of 3 cases of acute monocytic leukemia with untreated chronic lymphocytic leukemia/monoclonal B-cell lymphocytosis were reported with literatures review.
  
  
  RESULTS
  The patients presented with a history of anemia, bleeding and/or fever. Acute monocytic leukemia was diagnosed by bone marrow morphology, cytochemistry and pathology studies. Immunophenotyping by flow cytometry analysis showed a significant population of absolute B-lymphocyte count of > 5×10(9)/L in a patients, similar to that of chronic lymphocytic leukemia.
  
  
  CONCLUSIONS
  The association of acute monocytic leukemia and untreated chronic lymphocytic leukemia/monoclonal B-cell lymphocytosis was a rare event. The abnormal B lymphocytes was likely to be misdiagnosis. Thus, it was important to combine several kinds of laboratory studies, especially flow cytometry to identify this rare disorder.
authors: Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin, China.
authors: Xue-Jing
authors: XJ
authors: Chen
authors: Yan
authors: Y
authors: Liu
authors: Gui-Qing
authors: GQ
authors: Guo
authors: Qing-Nian
authors: QN
authors: Cheng
authors: Bing-Cheng
authors: BC
authors: Liu
authors: Dong
authors: D
authors: Lin
authors: Kai-Qi
authors: KQ
authors: Liu
authors: Ying-Chang
authors: YC
authors: Mi
authors: Jian-Xiang
authors: JX
authors: Wang
authors: Hui-Jun
authors: HJ
authors: Wang
mesh_terms: D000368:Aged; D001402:B-Lymphocytes / Q000473:pathology; D005260:Female; D006801:Humans; D007948:Leukemia, Monocytic, Acute / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D008218:Lymphocytosis / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged