title: Fox family ties.
abstract: The transcription factor Foxp3 plays an indispensible role in the differentiation of regulatory T (Treg) cells and the expression of their suppressive functions. In a recent article published in Nature, Ouyang et al. demonstrate that Treg cell differentiation is also enabled by transcriptional networks controlled by another Forkhead box family member, Foxo1.
authors: Section of Rheumatology, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA. william@mcw.edu
authors: Calvin B
authors: CB
authors: Williams
authors: Talal A
authors: TA
authors: Chatila
mesh_terms: D000818:Animals; D005260:Female; D051858:Forkhead Transcription Factors / Q000378:metabolism*; D008297:Male; D050378:T-Lymphocytes, Regulatory / Q000276:immunology* / Q000378:metabolism*; D014158:Transcription, Genetic
chemical_list: D051858:Forkhead Transcription Factors