title: Metabolic response to pegylated arginine deiminase in mesothelioma with promoter methylation of argininosuccinate synthetase.
authors: Barts Cancer Institute, Barts and The London School of Medicine, Queen Mary University of London, Charterhouse Square, London EC1M6BQ, England, UK. p.w.szlosarek@qmul.ac.uk
authors: Peter W
authors: PW
authors: Szlosarek
authors: Phuong
authors: P
authors: Luong
authors: Melissa M
authors: MM
authors: Phillips
authors: Marina
authors: M
authors: Baccarini
authors: Ellis
authors: E
authors: Stephen
authors: Teresa
authors: T
authors: Szyszko
authors: Michael T
authors: MT
authors: Sheaff
authors: Norbert
authors: N
authors: Avril
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001124:Argininosuccinate Synthase / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D001194:Asbestos / Q000009:adverse effects; D002945:Cisplatin / Q000008:administration & dosage; D002986:Clinical Trials as Topic; D019175:DNA Methylation; D017809:Fatal Outcome; D019788:Fluorodeoxyglucose F18; D005971:Glutamates / Q000008:administration & dosage; D006147:Guanine / Q000008:administration & dosage / Q000031:analogs & derivatives; D006801:Humans; D006867:Hydrolases / Q000627:therapeutic use*; D008297:Male; D008654:Mesothelioma / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000201:enzymology* / Q000209:etiology; D008875:Middle Aged; D009154:Mutation; D016273:Occupational Exposure / Q000009:adverse effects; D000068437:Pemetrexed; D016066:Pleural Effusion, Malignant / Q000209:etiology; D010997:Pleural Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000201:enzymology* / Q000209:etiology; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D049268:Positron-Emission Tomography / Q000379:methods*; D011401:Promoter Regions, Genetic; D019275:Radiopharmaceuticals
chemical_list: D005971:Glutamates; D019275:Radiopharmaceuticals; D000068437:Pemetrexed; D019788:Fluorodeoxyglucose F18; D001194:Asbestos; D011092:Polyethylene Glycols; D006147:Guanine; D006867:Hydrolases; C512527:ADI PEG20; D001124:Argininosuccinate Synthase; D002945:Cisplatin