title: Auto-tandem catalysis: synthesis of 4H-pyrido[1,2-a]pyrimidin-4-ones via copper-catalyzed aza-Michael addition-aerobic dehydrogenation-intramolecular amidation.
abstract: A copper-catalyzed domino synthesis of 4H-pyrido[1,2-a]pyrimidin-4-ones has been developed from 1,4-enediones and 2-aminoheterocycles with air as the oxidant.
authors: Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Hubei, Wuhan 430079, PR China.
authors: Yan
authors: Y
authors: Yang
authors: Wen-Ming
authors: WM
authors: Shu
authors: Shang-Bo
authors: SB
authors: Yu
authors: Fan
authors: F
authors: Ni
authors: Meng
authors: M
authors: Gao
authors: An-Xin
authors: AX
authors: Wu
mesh_terms: D000577:Amides / Q000737:chemistry*; D001372:Aza Compounds / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D010084:Oxidation-Reduction; D011744:Pyrimidinones / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000577:Amides; D001372:Aza Compounds; D011744:Pyrimidinones; D003300:Copper