title: Premenstrual syndrome and self-medication with opioids.
abstract: We have described a patient in opioid substitution treatment using heroin to treat her premenstrual complaints. After a short review of the diagnosis and etiology of premenstrual syndrome or premenstrual dysphoric disorder, the relation between premenstrual syndrome/premenstrual dysphoric disorder and opioid receptors is discussed. In the case of the patient described, increasing the dose of methadone in the premenstrual period produced significant clinical improvement.
authors: Novadic-Kentron, Network for Addiction Treatment Services, Vught, The Netherlands. rouhollah.qurishi@novadic-kentron.nl
authors: Rouhollah
authors: R
authors: Qurishi
authors: Christina
authors: C
authors: Sonneborn
authors: Marieke
authors: M
authors: de Jong-Arts
authors: Cornelis
authors: C
authors: de Jong
mesh_terms: D000328:Adult; D000342:Affective Symptoms / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D005260:Female; D006556:Heroin Dependence / Q000188:drug therapy*; D006801:Humans; D007508:Irritable Mood / Q000187:drug effects / Q000502:physiology; D008691:Methadone / Q000008:administration & dosage*; D058850:Opiate Substitution Treatment / Q000379:methods*; D011293:Premenstrual Syndrome / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology; D015813:Substance Abuse Detection; D016896:Treatment Outcome
chemical_list: D008691:Methadone