title: Distribution of H2S synthesis enzymes in the walls of cerebral arteries in rats.
abstract: The distribution of two enzymes involved in H(2)S synthesis, cystationine β-synthase (CBS) and cystationine γ-liase (CSE), was studied in the walls of the internal carotid artery, order I-V branches of the middle cerebral artery basin, and intracerebral vessels of adult Wistar rats. Immunohistochemical staining showed the presence of CBS in the endothelium of small pial arteries (order IV-V branches) and intracerebral arterioles and in the capillary walls, neurons, and vascular nerves. As for CSE, in the internal carotid artery and large (order I-II) pial branches it was found mainly in the tunica media myocytes, in order III-IV vessels in myocytes and endothelium, and in smaller pial and intracerebral vessels in the endothelium. Along with enzyme-positive vessels, many pial and intracerebral arteries contained no these enzymes in the walls.
authors: Department of Human Anatomy, Vladivostok State Medical University, Russia.
authors: V M
authors: VM
authors: Chertok
authors: A E
authors: AE
authors: Kotsyuba
mesh_terms: D000818:Animals; D002343:Carotid Artery, Internal / Q000378:metabolism; D002536:Cerebral Arteries / Q000201:enzymology* / Q000294:innervation / Q000378:metabolism; D003541:Cystathionine beta-Synthase / Q000378:metabolism*; D003542:Cystathionine gamma-Lyase / Q000378:metabolism*; D004730:Endothelium, Vascular / Q000378:metabolism*; D006862:Hydrogen Sulfide / Q000378:metabolism*; D007150:Immunohistochemistry; D008297:Male; D020768:Middle Cerebral Artery / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D017540:Tunica Media / Q000378:metabolism
chemical_list: D003541:Cystathionine beta-Synthase; D003542:Cystathionine gamma-Lyase; D006862:Hydrogen Sulfide