title: [Characteristics of pain in oncologic disease of the knee].
abstract: BACKGROUND
  10% of > 55-year-old adults suffer some kind of non-neoplastic knee pain and 75% of the musculoskeletal neoplastic disease develops in the knee.
  
  
  OBJECTIVE
  to identify clinical characteristics of knee pain in neoplastic knee pathology.
  
  
  METHODS
  after appropriate authorization of the Local Committee of Investigation and under informed consent, we made a crosssectional and a risk analysis study. We included 160 patients who were seeking medical help due to knee pain. They answered a standardized questionnaire relating to the characteristics of their pain symptomatology. Data were integrated into two groups with knee pain; a) neoplasic (cases, n = 65), b) non-neoplasic (controls, n = 95) and analyzed (SPSS v.15™). We used homogeneity tests between groups (p > 0.05); inferential analysis (Student t test, χ(2)) and risk assessment (OR), p ≤ 0.05, (CI 95%), Statistical power was > 0.80.
  
  
  RESULTS
  female gender predominated (55%); age was 40.3 ± 19.6 years. The most prevalent diagnoses were knee osteoarthritis 37% for non-neoplasic group; giant cell tumor 10% for benign neoplasic group and osteosarcoma 6.1% for neoplasic malignant group. Knee pain lasting < 4 months (OR 7.6; CI 95% 3.48-16.5) and severe intensity (OR 5.7; CI 95% 2.82-11.64), constant pain (OR 2.9; CI 95% 1.37-6.36), rapidly progressive fluctuation (OR 31; CI 95% 7.01-137) and nocturnal predominance (OR 7.72; CI 95% 3.2-18.5) were characteristics of neoplasic knee pain.
  
  
  CONCLUSIONS
  the neoplasic knee pain was characterized for a rapid onset, severe and constant pain, progressive, fluctuation and predominantly by night-time.
authors: Servicio de Tumores Óseos, Hospital de Ortopedia, Unidad Médica de Alta Especialidad (UMAE) Dr. Victorio de la Fuente Narváez, Distrito Federal, IMSS, Mexico.
authors: Gustavo
authors: G
authors: Rivera-Saldívar
authors: Rubén
authors: R
authors: Torres-González
authors: Silvestre
authors: S
authors: Fuentes-Figueroa
authors: Romeo
authors: R
authors: Técualt-Gómez
authors: Rubén Alonso
authors: RA
authors: Amaya-Zepeda
authors: Uriah
authors: U
authors: Guevara-López
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018771:Arthralgia / Q000453:epidemiology / Q000209:etiology*; D001859:Bone Neoplasms / Q000150:complications* / Q000453:epidemiology; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D005870:Giant Cell Tumors / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D007593:Joint Instability / Q000453:epidemiology / Q000209:etiology; D007719:Knee Joint / Q000473:pathology / Q000503:physiopathology; D008297:Male; D054220:Malformations of Cortical Development / Q000150:complications / Q000453:epidemiology; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000150:complications* / Q000453:epidemiology; D015831:Osteochondroma / Q000150:complications / Q000453:epidemiology; D012516:Osteosarcoma / Q000150:complications* / Q000453:epidemiology; D012306:Risk; D012494:Sampling Studies; D063189:Symptom Assessment; D055815:Young Adult