title: Insufficiency fracture associated with oncogenic osteomalacia.
abstract: Oncogenic osteomalacia is a rare paraneoplastic syndrome of systemic bone demineralization secondary to a tumor-induced dysregulation of phosphorus metabolism. The tumor's low prevalence, small size, and variable location often result in years of muscular weakness and bone pain before diagnosis. With complete treatment, patient's symptoms swiftly dissipate. We report the case of a 63-year-old previously healthy man with a 20-month course of musculoskeletal symptoms before diagnosis and resection of a posterior tibial tumor. Postoperatively, the patient had returned to his previous lifestyle when an insufficiency fracture required prophylactic stabilization.
authors: Medical University of South Carolina, Charleston, SC 29425, USA.
authors: Thomas
authors: T
authors: Niemeier
authors: Lee
authors: L
authors: Leddy
authors: Marcy
authors: M
authors: Bolster
authors: Russell
authors: R
authors: Chapin
mesh_terms: D001858:Bone Nails; D005264:Femoral Fractures / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D005594:Fracture Fixation, Intramedullary; D015775:Fractures, Stress / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009372:Neoplasms, Connective Tissue / Q000150:complications*; D010018:Osteomalacia; D010257:Paraneoplastic Syndromes; D016896:Treatment Outcome