title: Cost-effectiveness assessment of orphan drugs: a scientific and political conundrum.
authors: Steven
authors: S
authors: Simoens
authors: Eline
authors: E
authors: Picavet
authors: Marc
authors: M
authors: Dooms
authors: David
authors: D
authors: Cassiman
authors: Thomas
authors: T
authors: Morel
mesh_terms: D003362:Cost-Benefit Analysis; D003657:Decision Making; D006801:Humans; D009426:Netherlands; D009965:Orphan Drug Production / Q000191:economics*; D011057:Politics; D035583:Rare Diseases / Q000188:drug therapy; D012051:Reimbursement Mechanisms