title: A case of Liddle Syndrome.
abstract: Pediatric hypertension is usually secondary to an underlying identifiable cause, most often renal. Hypertension with low Plasma Rennin Activity (PRA), although rare, is important as it is often familial and is associated with single gene disorders (monogenic). It hence carries greater genetic implications for the family. The authors' hereby report a case of low PRA hypertension which was diagnosed as Liddle Syndrome, an autosomal dominant form of hereditary hypertension. Early detection and appropriate treatment may help to improve the long term morbidity and mortality in children with this condition.
authors: Pediatric Nephrology Division, Department of Pediatrics Unit II, Christian Medical College, Vellore, 632 004, South India.
authors: Rajiv
authors: R
authors: Sinha
authors: Indrayani
authors: I
authors: Salphale
authors: Indira
authors: I
authors: Agarwal
mesh_terms: D003937:Diagnosis, Differential; D020022:Genetic Predisposition to Disease; D006801:Humans; D007223:Infant; D056929:Liddle Syndrome / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D008297:Male