title: Direct access to enantioenriched spiroacetals through asymmetric relay catalytic three-component reaction.
abstract: The gold(I)/chiral Brønsted acid relay catalysis enabled a highly stereoselective three-component reaction of salicylaldehydes, anilines, and alkynols to give aromatic spiroacetals in high yields and stereoselectivities.
authors: Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei 230026, China.
authors: Hua
authors: H
authors: Wu
authors: Yu-Ping
authors: YP
authors: He
authors: Liu-Zhu
authors: LZ
authors: Gong
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D000814:Aniline Compounds / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D006046:Gold / Q000737:chemistry; D015394:Molecular Structure; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000447:Aldehydes; D000814:Aniline Compounds; D013141:Spiro Compounds; C013243:salicylaldehyde; D006046:Gold