title: Cardiac and pulmonary thrombosis during multidrug treatment in an idiopathic thrombocytopenic purpura patient.
abstract: Glucocorticosteroids, intravenous immunoglobulins, vincristine, danazol, and eltrombopag are used in refractory chronic idiopathic thrombocytopenic purpura (ITP). All those treatment modalities are susceptible for thrombosis generation. There is an increased risk of thrombosis in the diseases' natural course. The case we present is a resistant chronic ITP patient who developed pulmonary and intracardiac thrombosis during multidrug treatment. Risk of concomitant usage of drugs and rapid increase in platelet count are discussed.
authors: Department of Hematology, Eskisehir Osmangazi University School of Medicine , Eskisehir , Turkey.
authors: Neslihan
authors: N
authors: Andic
authors: Eren
authors: E
authors: Gunduz
authors: Olga Meltem
authors: OM
authors: Akay
authors: Deniz
authors: D
authors: Şahin
authors: Hava Üsküdar
authors: HÜ
authors: Teke
mesh_terms: D000328:Adult; D001565:Benzoates / Q000009:adverse effects / Q000627:therapeutic use; D003613:Danazol / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006834:Hydrazines / Q000009:adverse effects / Q000627:therapeutic use; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects / Q000627:therapeutic use; D008775:Methylprednisolone / Q000009:adverse effects / Q000627:therapeutic use; D011655:Pulmonary Embolism / Q000097:blood / Q000139:chemically induced*; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood* / Q000188:drug therapy* / Q000601:surgery; D011720:Pyrazoles / Q000009:adverse effects / Q000627:therapeutic use; D020246:Venous Thrombosis / Q000097:blood / Q000139:chemically induced*; D014750:Vincristine / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D001565:Benzoates; D006834:Hydrazines; D016756:Immunoglobulins, Intravenous; D011720:Pyrazoles; D014750:Vincristine; D003613:Danazol; C520809:eltrombopag; D008775:Methylprednisolone