title: Superficial acral fibromyxoma of the great toe: case report and mini-review of the literature.
abstract: Superficial acral fibromyxoma (SAF) is a rare, distinctive, benign soft tissue tumor with a predilection for the hands and feet, first described by Fetsch et al. in 2001. Histologically, SAF tumors are unencapsulated, mostly located in the dermis or subcutis, and composed of spindled and stellate-shaped cells with random, loose storiform and fascicular growth patterns. The stromal component of the tumor was Alcian blue-positive. The tumor cells were mostly immunopositive for CD34, vimentin, and CD99; often immunopositive for EMA; and immunonegative for S-100, HMB-45, SMA, desmin, and keratin. There have been 19 reports of 149 SAF cases in the English language literature. However, SAF is not widely recognized because it is an uncommon occurrence that has been described only relatively recently. Herein, we report a case of SAF and describe the clinicopathologic characteristics based on a review of published SAF cases from July 2001 to July 2011.
authors: Department of Dermatology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Japan.
authors: Yusuke
authors: Y
authors: Wakabayashi
authors: Noriaki
authors: N
authors: Nakai
authors: Hideya
authors: H
authors: Takenaka
authors: Norito
authors: N
authors: Katoh
mesh_terms: D005260:Female; D005350:Fibroma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D009260:Nail Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery