title: No association between bronchial asthma and HLA-DRB1, -DQB1 alleles in the Slovak population.
abstract: 109 patients (62 boys/men and 47 girls/women) suffering from bronchial asthma induced by pollen allergens were typed for HLA-DRB1 and -DQBl alleles, respectively, by a low resolution SSP technique. Frequencies of DRB1 alleles varied from 0.5 % to 16.1 %. The most frequent was HLA-DRB1*11 (16.1 %), the least frequent HLA-DRB1*09 (0.4 %). Occurrence rates of HLA-DQB1 alleles ranged from 2.3 % to 37.2 %, HLA-DQB1*03 being the most frequent (37.2 %) and DQB1*04 stood on the opposite pole (2.3 %). By comparing to occurrence rates in the healthy population, no statistically significant differences were disclosed (Tab. 2, Ref. 16).
authors: Department of Immunology, Comenius University School of Medicine, Bratislava, Slovakia. dzurilla@gmail.com
authors: M
authors: M
authors: Dzurilla
authors: M
authors: M
authors: Vrlík
authors: M
authors: M
authors: Homolová
authors: M
authors: M
authors: Buc
mesh_terms: D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000235:genetics* / Q000276:immunology; D002648:Child; D005260:Female; D005787:Gene Frequency; D059866:HLA-DQ beta-Chains / Q000032:analysis*; D059811:HLA-DRB1 Chains / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018154:Slovakia; D055815:Young Adult
chemical_list: D059866:HLA-DQ beta-Chains; C069051:HLA-DQB1 antigen; D059811:HLA-DRB1 Chains