title: [Hemodynamic stability in total intravenous propofol anesthesia with midazolam coinduction versus general balanced anaesthesia in laparoscopic cholecystectomy].
abstract: OBJECTIVE
  Laparoscopic cholecystectomy can be a greater challenge for anesthesiologist than for surgeon if the patient is ASA III with concomitant cardiovascular diseases. The aim of our study was to compare the effect of total intravenous anesthesia (TIVA--propofol with midazolam) and general balanced anesthesia (GBA--midazolam, thiopenton, nitrous oxide and 02) on hemodynamic stability in the ASA III patients who underwent laparoscopic cholecystectomy.
  
  
  METHODS
  In our study, 60 patients were randomized into two groups depending on whether they received TIVA or GBA. Heart rate, systolic, diastolic and mean arterial pressure were monitored continuously and recorded in five time intervals.
  
  
  RESULTS
  Statistical analysis showed that TIVA with propofol provides better hemodynamic stability (less than 10% deviation from basal values for each measured parameter) then GBA group (p < 0.01).
  
  
  CONCLUSIONS
  Total intravenous anesthesia with propofol provides better hemodynamic stability for ASA III patients with concomitant cardiovascular diseases then GBA.
authors: Klinika za anesteziologiju i intenzivnu terapiju, Vojnomedicinska akademija, Beograd, Srbija. maja.surbatovic@gmail.com
authors: Maja
authors: M
authors: Surbatović
authors: Zoran
authors: Z
authors: Vesić
authors: Dragan
authors: D
authors: Djordjević
authors: Sonja
authors: S
authors: Radaković
authors: Snjeiana
authors: S
authors: Zeba
authors: Dusko
authors: D
authors: Jovanović
authors: Marijan
authors: M
authors: Novaković
mesh_terms: D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous; D019162:Anesthetics, Combined; D018686:Anesthetics, Intravenous; D062186:Arterial Pressure; D058126:Balanced Anesthesia; D002318:Cardiovascular Diseases / Q000503:physiopathology*; D017081:Cholecystectomy, Laparoscopic; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008874:Midazolam; D008875:Middle Aged; D015742:Propofol
chemical_list: D019162:Anesthetics, Combined; D018686:Anesthetics, Intravenous; D008874:Midazolam; D015742:Propofol