title: A new phenolic glycoside from Chamaecyparis obtusa var. breviramea f. crippsii.
abstract: A new phenolic glycoside, 3-methoxyphenol 1-O-α-L-rhamnopyranosyl-(1→6)- O-β-D-glucopyranoside (1), was isolated from the 90% acetone extract of the branches and leaves of Chamaecyparis obtusa var. breviramea f. crippsii along with another 10 known phenolics 2-11. Their structures were determined mainly by means of MS, 1D- and 2D-NMR data. Cytotoxicities of compounds 3 and 5-11 were tested on BGC-823, Hela and A549 cancer cell lines, the results showed that compound 8 was bioactive and its IC(50) values were 6.9, 29.7 and 52.9 μM, respectively.
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Heilongtan, Kunming 650201, China. zymei@xtbg.ac.cn
authors: Yu-Mei
authors: YM
authors: Zhang
authors: Jian
authors: J
authors: Xu
authors: Lin
authors: L
authors: Xiao
authors: Guang-Zhi
authors: GZ
authors: Zeng
authors: Zhang-Hua
authors: ZH
authors: Sun
authors: Ning-Hua
authors: NH
authors: Tan
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D002470:Cell Survival / Q000187:drug effects; D029780:Chamaecyparis / Q000737:chemistry*; D004187:Disaccharides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D020128:Inhibitory Concentration 50; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry
chemical_list: D004187:Disaccharides; D010936:Plant Extracts