title: Influence of RGD grafting on biocompatibility of oxidized cellulose scaffold.
abstract: Cellulose powder was oxidized by NO2 gas and the porous scaffold was fabricated by dry pressing. RGD peptide was immobilized on the surface of scaffold by grafting to make a hybrid scaffold. The hybrid scaffold was characterized by SEM and FTIR and its biocompatibility was examined through MTT assay. FTIR results proved oxidization of cellulose and bonding between scaffold surface and RGD. Porous microstructure having suitable size was confirmed by SEM. The results by MTT showed significant increase of viable cells on hybrid scaffold. Porous structure and high biocompatibility were the benefits of scaffold in bone tissue engineering.
authors: Department of Radiology, School of Paramedical Sciences, Kurdistan University of Medical Sciences , Sanandaj , Iran.
authors: Mozaffar
authors: M
authors: Mahmoodi
authors: Seyyed Mohammad
authors: SM
authors: Hossainalipour
authors: Mohammad Reza
authors: MR
authors: Naimi-Jamal
authors: Saeed
authors: S
authors: Samani
authors: Ali
authors: A
authors: Samadikuchaksaraei
authors: Hamid Reza
authors: HR
authors: Rezaie
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry* / Q000633:toxicity; D002460:Cell Line; D049109:Cell Proliferation / Q000187:drug effects; D002482:Cellulose / Q000737:chemistry* / Q000633:toxicity; D006801:Humans; D008422:Materials Testing; D009842:Oligopeptides / Q000737:chemistry*; D010084:Oxidation-Reduction; D013329:Structure-Activity Relationship; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D009842:Oligopeptides; C047981:arginyl-glycyl-aspartic acid; D002482:Cellulose