title: Outcomes among patients treated for gastric adenocarcinoma during the last decade.
abstract: OBJECTIVE
  To evaluate the outcomes among patients treated for gastric adenocarcinoma in a referral hospital, and to identify possible trends during the last decade.
  
  
  METHODS
  All patients evaluated for gastric adenocarcinoma during the period 1999-2009 were included.
  
  
  RESULTS
  Of 397 patients, 52% were curatively resected. Crude 5-year survival for the first 6 years period was 38.7% (CI 29.5-47.9), for the last 5 years, 49.2% (CI 38.8-59.6). Time period (P = 0.013), age (P < 0.001) and disease stage (P < 0.001), were significant predictors of long-term survival rates. Among curatively resected, in-hospital mortality was reduced from 8.5% in the first period to 2.0% in the last one (P = 0.037). There was a significant increase in the use of primary stents from the first to the last period (P = 0.006), paralleled by a significant reduction in the number of explorative laparotomies or bypass procedures (P < 0.001).
  
  
  CONCLUSIONS
  During the last decade, long-term survival rates improved among patients curatively resected for gastric adenocarcinoma, and in-hospital mortality was substantially reduced. For patients in a non-curative situation, there was a significant shift from explorative laparotomies or bypass procedures to primary use of stents.
authors: Department of Gastrointestinal Surgery, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. erling.bringeland@stolav.no
authors: E A
authors: EA
authors: Bringeland
authors: H H
authors: HH
authors: Wasmuth
authors: G
authors: G
authors: Johnsen
authors: T B
authors: TB
authors: Johnsen
authors: I S
authors: IS
authors: Juel
authors: P
authors: P
authors: Mjønes
authors: P E
authors: PE
authors: Uggen
authors: B
authors: B
authors: Ystgaard
authors: J E
authors: JE
authors: Grønbech
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D016896:Treatment Outcome