title: Prediction of newly developed acute renal failure using serum phosphorus concentrations after living-donor liver transplantation.
abstract: OBJECTIVE
  This retrospective study investigated the predictive role of serum phosphorus concentration for acute renal failure (ARF), defined by the Risk Injury Failure Loss End-stage kidney disease (RIFLE) criteria, after living-donor liver transplantation (LDLT).
  
  
  METHODS
  Perioperative factors, including serum phosphorus concentrations, in LDLT recipients without pre-existing renal dysfunction were retrospectively analysed and compared between patients with or without post-LDLT ARF.
  
  
  RESULTS
  A total of 45 patients out of 350 (12.9%) met the RIFLE ARF criteria and experienced significantly higher postoperative mortality, longer intensive care unit stay and more frequent graft dysfunction than those patients without post-LDLT ARF. Multivariate logistic regression analyses showed that a serum phosphorus concentration ≥ 4.5 mg/dl on postoperative day 1 (relative risk [RR] 5.31; 95% confidence interval [CI] 2.56, 11.03), a preoperative model for end-stage liver disease score 20 points (RR 4.17, 95% CI 2.04, 8.52), and packed red blood cell transfusion 10 units (RR 2.55, 95% CI 1.13, 5.88) were independent risk factors for post-LDLT ARF.
  
  
  CONCLUSIONS
  Hyperphosphataemia on postoperative day 1 could be an early and simple indicator of ARF occurrence after LDLT.
authors: Department of Anaesthesiology and Pain Medicine, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Republic of Korea.
authors: S H
authors: SH
authors: Hong
authors: C O
authors: CO
authors: Park
authors: C S
authors: CS
authors: Park
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood* / Q000209:etiology*; D005260:Female; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects* / Q000401:mortality; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D010758:Phosphorus / Q000097:blood*; D011183:Postoperative Complications / Q000453:epidemiology; D012189:Retrospective Studies
chemical_list: D010758:Phosphorus