title: Calciphylaxis - a challenging & solvable task for plastic surgery? A case report.
abstract: BACKGROUND
  Calciphylaxis (calcific uremic arteriolopathy) is rare and its pathogenesis is not fully understood. Indeed, Calciphylaxis presents a challenge through the course of its management which involve different specialities but unfortunately this disease so far has a poor prognosis. We herein present, in this case report, a multidisciplinary approach involving plastic surgeons with special regards to reconstructive approach after debridement procedures.
  
  
  METHODS
  We present a 21 years old male with a BMI of 38,2, who was transferred to our department from another hospital. Calciphylaxis has been diagnosed after receiving anticoagulation with phenprocoumon after a single event of pulmonary embolism. The INR on admission was 1,79. He had necrotic spots on both sides of the abdominal wall and on both thighs medially. During this time he underwent several reconstructive procedures in our department.
  
  
  CONCLUSIONS
  It can be suggested that this agonizing disease needs indeed a multidisciplinary approach involving Nephrologists, Dermatologists, Intensive Care Physicians and Plastic Surgeons, taking into consideration that surgical correction can achieve further improvement in a specialized centre. Notwithstanding, further cohort studies should be approached clinically to insight the light on this disease with special regard to the prognosis after this approach.
authors: Department of Plastic Surgery and Hand Surgery, Burn Center, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074 Aachen, Germany. s.tsolakidis@me.com
authors: Savas
authors: S
authors: Tsolakidis
authors: Gerrit
authors: G
authors: Grieb
authors: Andrzej
authors: A
authors: Piatkowski
authors: Ziyad
authors: Z
authors: Alharbi
authors: Erhan
authors: E
authors: Demir
authors: David
authors: D
authors: Simons
authors: Norbert
authors: N
authors: Pallua
mesh_terms: D034861:Abdominal Wall; D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects; D002115:Calciphylaxis / Q000139:chemically induced* / Q000601:surgery*; D006801:Humans; D008297:Male; D010644:Phenprocoumon / Q000009:adverse effects*; D011655:Pulmonary Embolism / Q000188:drug therapy; D019651:Plastic Surgery Procedures / Q000379:methods*; D016038:Skin Transplantation / Q000379:methods*; D013848:Thigh; D055815:Young Adult
chemical_list: D000925:Anticoagulants; D010644:Phenprocoumon