title: Inspired by nature: fundamentals in nanotechnology design to overcome biological barriers.
abstract: Synergy between nanotechnology and drug delivery has created a multitude of novel drug-delivery systems with great therapeutic potential. However, directing these systems across the biological barriers to the target site has proven difficult. Nanotechnology is looking for inspiration in natural systems that have evolved to overcome such barriers. Here, we review nature-inspired strategies and fundamental features common to successful drug-delivery systems across biological barriers.
authors: The Krebs Institute, MBB, University of Sheffield, Sheffield, UK.
authors: Milagros
authors: M
authors: Avila-Olias
authors: Carla
authors: C
authors: Pegoraro
authors: Giuseppe
authors: G
authors: Battaglia
authors: Irene
authors: I
authors: Canton
mesh_terms: D000818:Animals; D001812:Blood-Brain Barrier; D016503:Drug Delivery Systems; D011992:Endosomes / Q000378:metabolism; D006801:Humans; D007113:Immunity, Innate; D008081:Liposomes / Q000008:administration & dosage; D036103:Nanotechnology; D009895:Opsonin Proteins / Q000008:administration & dosage; D011108:Polymers / Q000008:administration & dosage
chemical_list: D008081:Liposomes; D009895:Opsonin Proteins; D011108:Polymers