title: A heterozygous moth genome provides insights into herbivory and detoxification.
abstract: How an insect evolves to become a successful herbivore is of profound biological and practical importance. Herbivores are often adapted to feed on a specific group of evolutionarily and biochemically related host plants, but the genetic and molecular bases for adaptation to plant defense compounds remain poorly understood. We report the first whole-genome sequence of a basal lepidopteran species, Plutella xylostella, which contains 18,071 protein-coding and 1,412 unique genes with an expansion of gene families associated with perception and the detoxification of plant defense compounds. A recent expansion of retrotransposons near detoxification-related genes and a wider system used in the metabolism of plant defense compounds are shown to also be involved in the development of insecticide resistance. This work shows the genetic and molecular bases for the evolutionary success of this worldwide herbivore and offers wider insights into insect adaptation to plant feeding, as well as opening avenues for more sustainable pest management.
authors: Institute of Applied Ecology, Fujian Agriculture and Forestry University, Fuzhou, China. msyou@iae.fjau.edu.cn
authors: Minsheng
authors: M
authors: You
authors: Zhen
authors: Z
authors: Yue
authors: Weiyi
authors: W
authors: He
authors: Xinhua
authors: X
authors: Yang
authors: Guang
authors: G
authors: Yang
authors: Miao
authors: M
authors: Xie
authors: Dongliang
authors: D
authors: Zhan
authors: Simon W
authors: SW
authors: Baxter
authors: Liette
authors: L
authors: Vasseur
authors: Geoff M
authors: GM
authors: Gurr
authors: Carl J
authors: CJ
authors: Douglas
authors: Jianlin
authors: J
authors: Bai
authors: Ping
authors: P
authors: Wang
authors: Kai
authors: K
authors: Cui
authors: Shiguo
authors: S
authors: Huang
authors: Xianchun
authors: X
authors: Li
authors: Qing
authors: Q
authors: Zhou
authors: Zhangyan
authors: Z
authors: Wu
authors: Qilin
authors: Q
authors: Chen
authors: Chunhui
authors: C
authors: Liu
authors: Bo
authors: B
authors: Wang
authors: Xiaojing
authors: X
authors: Li
authors: Xiufeng
authors: X
authors: Xu
authors: Changxin
authors: C
authors: Lu
authors: Min
authors: M
authors: Hu
authors: John W
authors: JW
authors: Davey
authors: Sandy M
authors: SM
authors: Smith
authors: Mingshun
authors: M
authors: Chen
authors: Xiaofeng
authors: X
authors: Xia
authors: Weiqi
authors: W
authors: Tang
authors: Fushi
authors: F
authors: Ke
authors: Dandan
authors: D
authors: Zheng
authors: Yulan
authors: Y
authors: Hu
authors: Fengqin
authors: F
authors: Song
authors: Yanchun
authors: Y
authors: You
authors: Xiaoli
authors: X
authors: Ma
authors: Lu
authors: L
authors: Peng
authors: Yunkai
authors: Y
authors: Zheng
authors: Yong
authors: Y
authors: Liang
authors: Yaqiong
authors: Y
authors: Chen
authors: Liying
authors: L
authors: Yu
authors: Younan
authors: Y
authors: Zhang
authors: Yuanyuan
authors: Y
authors: Liu
authors: Guoqing
authors: G
authors: Li
authors: Lin
authors: L
authors: Fang
authors: Jingxiang
authors: J
authors: Li
authors: Xin
authors: X
authors: Zhou
authors: Yadan
authors: Y
authors: Luo
authors: Caiyun
authors: C
authors: Gou
authors: Junyi
authors: J
authors: Wang
authors: Jian
authors: J
authors: Wang
authors: Huanming
authors: H
authors: Yang
authors: Jun
authors: J
authors: Wang
mesh_terms: D000220:Adaptation, Biological / Q000235:genetics*; D000818:Animals; D001483:Base Sequence; D002681:China; D022202:Chromosomes, Artificial, Bacterial; D019295:Computational Biology; D019143:Evolution, Molecular; D020224:Expressed Sequence Tags; D005260:Female; D020869:Gene Expression Profiling; D014644:Genetic Variation; D016678:Genome / Q000235:genetics*; D005961:Glucosinolates / Q000378:metabolism*; D060434:Herbivory / Q000235:genetics*; D006579:Heterozygote; D008297:Male; D058977:Molecular Sequence Annotation; D008969:Molecular Sequence Data; D009036:Moths / Q000235:genetics* / Q000378:metabolism; D009154:Mutation / Q000235:genetics; D010571:Pest Control / Q000379:methods; D010802:Phylogeny; D020641:Polymorphism, Single Nucleotide; D060888:Real-Time Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D013429:Sulfatases / Q000235:genetics
chemical_list: D005961:Glucosinolates; D013429:Sulfatases