title: TG13 antimicrobial therapy for acute cholangitis and cholecystitis.
abstract: Therapy with appropriate antimicrobial agents is an important component in the management of patients with acute cholangitis and/or acute cholecystitis. In the updated Tokyo Guidelines (TG13), we recommend antimicrobial agents that are suitable from a global perspective for management of these infections. These recommendations focus primarily on empirical therapy (presumptive therapy), provided before the infecting isolates are identified. Such therapy depends upon knowledge of both local microbial epidemiology and patient-specific factors that affect selection of appropriate agents. These patient-specific factors include prior contact with the health care system, and we separate community-acquired versus healthcare-associated infections because of the higher risk of resistance in the latter. Selection of agents for community-acquired infections is also recommended on the basis of severity (grades I-III). Free full-text articles and a mobile application of TG13 are available via http://www.jshbps.jp/en/guideline/tg13.html.
authors: Center for Clinical Infectious Diseases, Jichi Medical University, 3311-1, Yakushiji, Shimotsuke, Tochigi, 329-0431, Japan. hgomi-oky@umin.ac.jp
authors: Harumi
authors: H
authors: Gomi
authors: Joseph S
authors: JS
authors: Solomkin
authors: Tadahiro
authors: T
authors: Takada
authors: Steven M
authors: SM
authors: Strasberg
authors: Henry A
authors: HA
authors: Pitt
authors: Masahiro
authors: M
authors: Yoshida
authors: Shinya
authors: S
authors: Kusachi
authors: Toshihiko
authors: T
authors: Mayumi
authors: Fumihiko
authors: F
authors: Miura
authors: Seiki
authors: S
authors: Kiriyama
authors: Masamichi
authors: M
authors: Yokoe
authors: Yasutoshi
authors: Y
authors: Kimura
authors: Ryota
authors: R
authors: Higuchi
authors: John A
authors: JA
authors: Windsor
authors: Christos
authors: C
authors: Dervenis
authors: Kui-Hin
authors: KH
authors: Liau
authors: Myung-Hwan
authors: MH
authors: Kim
mesh_terms: D000208:Acute Disease; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002761:Cholangitis / Q000188:drug therapy*; D041881:Cholecystitis, Acute / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans
chemical_list: D000890:Anti-Infective Agents