title: Development and application of a new 25,27-bis(L-phenylalaninemethylester-N-carbonylmethoxy)-26,28-dihydroxy-para-tert-butylcalix[4]arene stationary phase.
abstract: A 25,27-bis(L-phenylalaninemethylester-N-carbonylmethoxy)-26,28-dihydroxy- para-tert-butylcalix[4]arene-bonded silica gel stationary phase was synthesized, structurally characterized and used for LC. Its separation mechanism was studied and compared with octadecyl-bonded stationary phase, as well as our previously prepared para-tert-butylcalix[4]arene-1,2-crown-4 stationary phase. Meanwhile, the chromatographic behaviors were investigated by using polycyclic aromatic hydrocarbons, monosubstituted benzenes, anilines, phenols, Tanaka tests solutes, fluoroquinolones, and flavonoids as probes. Mechanisms involved in the chromatographic separation included hydrophobic, π-π and π-electron transfer, hydrogen bonding, and inclusion interactions. Moreover, the column was successfully employed for the analysis of the illegal additive of melamine in milk product.
authors: College of Chemistry and Molecular Engineering, Key Laboratory of Chemical Biology and Organic Chemistry of Henan, Zhengzhou University, Zhengzhou, P R China.
authors: Kai
authors: K
authors: Hu
authors: Yanhao
authors: Y
authors: Zhang
authors: Junwei
authors: J
authors: Liu
authors: Kangkang
authors: K
authors: Chen
authors: Wenjie
authors: W
authors: Zhao
authors: Weixia
authors: W
authors: Zhu
authors: Zhichao
authors: Z
authors: Song
authors: Baoxian
authors: B
authors: Ye
authors: Shusheng
authors: S
authors: Zhang
mesh_terms: D000327:Adsorption; D000818:Animals; D047250:Calixarenes / Q000138:chemical synthesis / Q000737:chemistry*; D002417:Cattle; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation / Q000379:methods*; D005506:Food Contamination / Q000032:analysis*; D041943:Infant Formula / Q000737:chemistry*; D008892:Milk / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D014227:Triazines / Q000032:analysis*
chemical_list: D011108:Polymers; D014227:Triazines; D047250:Calixarenes; C011907:melamine