title: tRNA modifications: necessary for correct tRNA-derived fragments during the recovery from stress?
abstract: Endonuclease-mediated tRNA fragmentation has been observed in many species suggesting functional importance for tRNA fragments. The size distribution of tRNA-derived fragments indicates the existence of mechanisms that protect tRNAs and their fragments from total degradation by exonucleases. Could post-transcriptional modifications be important for the controlled processing of tRNAs?
authors: Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany.
authors: Zeljko
authors: Z
authors: Durdevic
authors: Matthias
authors: M
authors: Schaefer
mesh_terms: D006801:Humans; D009690:Nucleic Acid Conformation; D014176:Protein Biosynthesis; D012323:RNA Processing, Post-Transcriptional; D012343:RNA, Transfer / Q000737:chemistry* / Q000235:genetics*; D013312:Stress, Physiological / Q000235:genetics*
chemical_list: D012343:RNA, Transfer