title: Crohn disease and the gynecologic patient.
abstract: Although Crohn disease (CD) is considered an inflammatory bowel disease, extraintestinal gynecologic manifestations are varied, frequent, and oftentimes difficult to manage. Its predilection for young and reproductive-age women makes it an important disease process for the gynecologist to understand, as its complications can have long-term repercussions on the developmental, sexual, reproductive, and psychological health of affected women. Patients may present with a variety of vulvovaginal, perineal, perianal, and urologic complaints. Perianal involvement from an intestinal fistula is the most common skin manifestation seen in CD. Other gynecologic manifestations include metastatic CD and rectovaginal and urovaginal fistulas. Recognition and accurate diagnosis of extraintestinal gynecologic manifestations, as well as a good understanding of the gynecologic effects of chronic disease, are necessary for optimal management. The article provides an overview of CD and highlights the gynecologic considerations in caring for women affected by this disease.
authors: Department of Obstetrics and Gynecology, St Luke's University Health Network, Bethlehem, PA, USA.
authors: Cleve
authors: C
authors: Sides
authors: Mari Charisse
authors: MC
authors: Trinidad
authors: Leo
authors: L
authors: Heitlinger
authors: James
authors: J
authors: Anasti
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D053704:Capsule Endoscopy / Q000379:methods; D003424:Crohn Disease / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D019468:Disease Management; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging / Q000379:methods; D010502:Perineum / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D012006:Rectovaginal Fistula / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D060728:Reproductive Health; D014570:Urologic Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D014623:Vaginal Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D014626:Vaginal Smears; D014845:Vulvar Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D016387:Women's Health
chemical_list: D000900:Anti-Bacterial Agents; D007155:Immunologic Factors