title: [The interest of maintenance electroconvulsive therapy in mood disorders].
abstract: Maintenance electroconvulsive therapy (M-ECT) is a treatment indicated for the treatment and prevention of recurrent depression in patients who either do not respond or do not tolerate psychotropic medication. We evaluated, retrospectively, clinical response to a 6-month minimum course of M-ECT in 25 patients with a diagnosis of bipolar disorder or schizoaffective disorder according to DSM IV-TR criterion. Our study demonstrated a significant improvement of Global Assessment of functioning (GAF) scores after a six month minimum course of M-ECT (34.8 ± 12.6 vs 65.6 ± 10.8; P<0.05) as well as Brief Psychiatric Rating Scale scores (BPRS): 79.3 ± 12.4 vs 43.4 ± 10.2; P<0.05). We observed a slight increase of Mini Mental State Examination (MMSE) scores after M-ECT; nonetheless, it was not statistically significant (24.2 ± 2.4 vs 26.2 ± 2.4; P=0.2). Regarding the mean duration of hospitalizations, we showed a statistically significant decrease in the median number of days of hospitalization (72 [59-93.50] days before M-ECT vs 43 [25-76] days since the first M-ECT; P=0.017). Maintenance ECT allowed a significant improvement in psychiatric symptoms and global functioning of the patients included in this study, as well as a decrease in the number of days of hospitalization. However, our pattern is limited because of its small size; so, further prospective studies in this field, including larger population is highly recommended.
authors: Service hospitalo-universitaire de santé mentale et de thérapeutique, faculté de médecine Paris-Descartes, université Paris-Descartes, centre hospitalier Sainte-Anne, 7, rue Cabanis, 75674 Paris cedex 14, France.
authors: H
authors: H
authors: Zaki
authors: O
authors: O
authors: Sentissi
authors: J-P
authors: JP
authors: Olié
authors: H
authors: H
authors: Lôo
authors: F
authors: F
authors: Mouaffak
authors: R
authors: R
authors: Gaillard
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001714:Bipolar Disorder / Q000175:diagnosis / Q000523:psychology / Q000628:therapy*; D003131:Combined Modality Therapy; D015897:Comorbidity; D061218:Depressive Disorder, Treatment-Resistant / Q000175:diagnosis / Q000523:psychology / Q000628:therapy*; D004565:Electroconvulsive Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000175:diagnosis / Q000523:psychology / Q000628:therapy*; D011619:Psychotropic Drugs / Q000627:therapeutic use; D012189:Retrospective Studies; D055502:Secondary Prevention
chemical_list: D011619:Psychotropic Drugs
keywords: Affective disorders; Continuation ECT; ECT de consolidation; ECT de maintenance; Electroconvulsivotherapy; Maintenance ECT; Schizoaffective disorders; Troubles de l’humeur; Troubles schizoaffectifs; Électroconvulsivothérapie