title: High loading of uniformly dispersed Pt nanoparticles on polydopamine coated carbon nanotubes and its application in simultaneous determination of dopamine and uric acid.
abstract: Multiwalled carbon nanotubes (MWCNT) were homogeneously covered with a bio-functional polydopamine (PDOP) by a simple dip-coating approach in mild basic solution. Then, uniformly dispersed and highly loaded platinum nanoparticles (PtNPs) were deposited on MWCNT@PDOP by a mild reductant, and were characterized by transmission electron microscopy and x-ray photoelectron spectroscopy. Afterwards, this nanocomposite was modified on the glass carbon electrode and applied to simultaneously determine dopamine (DA) and uric acid (UA) by differential pulse voltammetry (DPV). Results showed that a linear electro-oxidation response was found for DA and UA in the range of 0.25-20 μM and 0.3-13 μM with the detection limit (S/N = 3) of 0.08 μM and 0.12 μM, respectively. In addition, the detection sensitivities for DA and UA by DPV were 1.03 μA μM(-1) and 2.09 μA μM(-1), respectively, which were much higher than those from a cyclic voltammogram. Finally, the reproducibility and stability of the nanocomposite were also evaluated, demonstrating that such MWCNT@PDOP@PtNPs can be a promising candidate for advanced electrode material in electrochemical sensing and other electrocatalytic applications.
authors: Institute of Biomaterials, College of Sciences, South China Agricultural University, Guangzhou 510642, Guangdong Province, People's Republic of China.
authors: Mouhong
authors: M
authors: Lin
authors: Haoliang
authors: H
authors: Huang
authors: Yingju
authors: Y
authors: Liu
authors: Canjian
authors: C
authors: Liang
authors: Shidong
authors: S
authors: Fei
authors: Xiaofen
authors: X
authors: Chen
authors: Chunlin
authors: C
authors: Ni
mesh_terms: D004298:Dopamine / Q000032:analysis*; D055664:Electrochemical Techniques / Q000379:methods*; D004566:Electrodes; D007211:Indoles / Q000737:chemistry*; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure; D010984:Platinum / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D014527:Uric Acid / Q000032:analysis*
chemical_list: D007211:Indoles; D037742:Nanotubes, Carbon; D011108:Polymers; C568283:polydopamine; D014527:Uric Acid; D010984:Platinum; D004298:Dopamine