title: An efficient synthesis of optically active trifluoromethyl aldimines via asymmetric biomimetic transamination.
abstract: This communication describes a chiral base-catalyzed asymmetric [1,3]-proton shift of trifluoromethyl ketimines, giving a wide variety of trifluoromethyl aldimines containing various functional groups with up to 94% ee.
authors: Beijing National Laboratory of Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors: Mao
authors: M
authors: Liu
authors: Jing
authors: J
authors: Li
authors: Xiao
authors: X
authors: Xiao
authors: Ying
authors: Y
authors: Xie
authors: Yian
authors: Y
authors: Shi
mesh_terms: D000586:Amination; D000588:Amines / Q000737:chemistry; D040761:Biomimetic Materials / Q000737:chemistry*; D002384:Catalysis; D018360:Crystallography, X-Ray; D007097:Imines / Q000737:chemistry*; D008968:Molecular Conformation; D009570:Nitriles / Q000737:chemistry*; D011522:Protons; D013237:Stereoisomerism
chemical_list: D000588:Amines; D007097:Imines; D009570:Nitriles; D011522:Protons; C542835:ketimine