title: Synthesis and activity of proteasome inhibitors.
abstract: Among its various catalytic activities, "chymotrypsin-like" activity of proteasome, a large multicatalytic proteinase complex has emerged as the focus of drug discovery efforts in cancer therapy. Herein, we report results from our investigation on a series of peptidomimetic inhibitors.
authors: Cephalon Inc. , West Chester, PA , USA.
authors: Derek
authors: D
authors: Dunn
authors: Mohamed
authors: M
authors: Iqbal
authors: Sankar
authors: S
authors: Chatterjee
mesh_terms: D061988:Proteasome Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology*
chemical_list: D061988:Proteasome Inhibitors