title: Bioactives from probiotics for dermal health: functions and benefits.
abstract: Probiotics have been extensively reviewed for decades, emphasizing on improving general gut health. Recently, more studies showed that probiotics may exert other health-promoting effects beyond gut well-being, attributed to the rise of the gut-brain axis correlations. Some of these new benefits include skin health such as improving atopic eczema, atopic dermatitis, healing of burn and scars, skin-rejuvenating properties and improving skin innate immunity. Increasing evidence has also showed that bacterial compounds such as cell wall fragments, their metabolites and dead bacteria can elicit certain immune responses on the skin and improve skin barrier functions. This review aimed to underline the mechanisms or the exact compounds underlying the benefits of bacterial extract on the skin based on evidences from in vivo and in vitro studies. This review could be of help in screening of probiotic strains with potential dermal enhancing properties for topical applications.
authors: School of Industrial Technology, Universiti Sains Malaysia, Penang, Malaysia.
authors: L-C
authors: LC
authors: Lew
authors: M-T
authors: MT
authors: Liong
mesh_terms: D019342:Acetic Acid / Q000494:pharmacology; D000279:Administration, Cutaneous; D001419:Bacteria / Q000737:chemistry; D003931:Diacetyl / Q000494:pharmacology; D006801:Humans; D006820:Hyaluronic Acid / Q000494:pharmacology; D019344:Lactic Acid / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000494:pharmacology; D010457:Peptidoglycan / Q000494:pharmacology; D019936:Probiotics / Q000494:pharmacology*; D012867:Skin / Q000276:immunology* / Q000382:microbiology*; D012879:Skin Physiological Phenomena; D013108:Sphingomyelin Phosphodiesterase / Q000494:pharmacology; D013682:Teichoic Acids / Q000494:pharmacology
chemical_list: D008070:Lipopolysaccharides; D010457:Peptidoglycan; D013682:Teichoic Acids; D019344:Lactic Acid; C009900:lipoteichoic acid; D006820:Hyaluronic Acid; D013108:Sphingomyelin Phosphodiesterase; D003931:Diacetyl; D019342:Acetic Acid