title: Immunosuppression-mediated hepatitis B reactivation diagnosed following an investigation into suspected transfusion-transmitted hepatitis B.
abstract: In August 2006, the regional unit for nosocomial infection control (ARLIN) was notified of a case of symptomatic acute hepatitis B (HBV) infection in an immunosuppressed 87-year-old patient who had received a blood transfusion five months previously. Immunosuppression for the treatment of a variety of conditions is increasing. Immunosuppressed patients should be investigated for previous HBV infection and given pre-emptive therapy where indicated. We report our experience investigating a case of HBV reactivation in an immunosuppressed patient. We describe the investigation and highlight the continued need for vigilance for HBV reactivation in immunosuppressed patients who may present to a range of clinicians.
authors: Réseau Franc-Comtois de Lutte contre les Infections Nosocomiales, centre hospitalier universitaire, Besançon, France. n1floretbassissi@chu-besancon.fr
authors: N
authors: N
authors: Floret
authors: J P
authors: JP
authors: Cervoni
authors: F
authors: F
authors: Sheppard
authors: M F Leconte
authors: MF
authors: Des Floris
authors: F
authors: F
authors: Duchêne
mesh_terms: D000369:Aged, 80 and over; D006509:Hepatitis B / Q000139:chemically induced* / Q000276:immunology; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D014775:Virus Activation
chemical_list: D007166:Immunosuppressive Agents