title: NICE guidelines for imaging studies in children with UTI adequate only in boys under the age of 6 months.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the applicability of the National Institute for Health and Clinical Excellence (NICE) guidelines for imaging studies in children under the age of three with first urinary tract infection (UTI).
  
  
  METHODS
  In our cohort of 112 patients, we gathered data regarding the occurrence of indications for ultrasonography (US) and voiding cystourethrography (VCUG) according to the NICE guidelines, dimercaptosuccinic acid (DMSA) scintigraphy examinations, UTI recurrence, antimicrobial prophylaxis (AMP), anti-reflux procedures, and other urological procedures.
  
  
  RESULTS
  If the NICE guidelines had been applied, 13 of the 25 patients (52 %) with vesicoureteral reflux (VUR), including 6 of the 12 patients (50 %) with dilating VUR and 3 of the 4 patients who underwent endoscopic anti-reflux treatment, would have been missed, and a negative VCUG would have been avoided in 25 of the 42 patients (60 %) with no VUR. None of the missed diagnoses occurred in the younger boys' group.
  
  
  CONCLUSIONS
  Based on these preliminary analyses, we feel that the NICE guidelines for imaging studies in children under 3 years old with UTI may be applicable to clinical use only in boys under 6 months of age. For other patients the guidelines were unsuccessful.
authors: Turku University Hospital, Turku, Finland. mtrist@utu.fi
authors: Marko Tapani
authors: MT
authors: Ristola
authors: Timo
authors: T
authors: Hurme
mesh_terms: D002675:Child, Preschool; D015331:Cohort Studies; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007668:Kidney / Q000000981:diagnostic imaging; D008297:Male; D017410:Practice Guidelines as Topic; D011859:Radiography; D011877:Radionuclide Imaging; D004113:Succimer; D014463:Ultrasonography; D014521:Urethra / Q000000981:diagnostic imaging; D001743:Urinary Bladder / Q000000981:diagnostic imaging; D014551:Urinary Tract / Q000000981:diagnostic imaging; D014552:Urinary Tract Infections / Q000150:complications*; D014554:Urination; D014718:Vesico-Ureteral Reflux / Q000175:diagnosis* / Q000601:surgery
chemical_list: D004113:Succimer