title: Effect of Intrafix® SafeSet infusion apparatus on phlebitis in a neurological intensive care unit: a case-control study.
abstract: OBJECTIVE
  To investigate the effect of the Intrafix(®) SafeSet infusion apparatus on the incidence of phlebitis in patients being intravenously infused in a neurological intensive care unit (ICU).
  
  
  METHODS
  Patients aged > 12 years, with no history of diabetes mellitus and no existing phlebitis, requiring a daily peripheral intravenous infusion of ≥ 8 h with the total period lasting ≥ 3 days, were enrolled. Infusions were performed using the Intrafix(®) SafeSet or normal infusion apparatus. Incidence of phlebitis (scored according to the Infusion Nursing Standards of Practice of the American Infusion Nurses Society) was analysed.
  
  
  RESULTS
  Patients (n = 1545) were allocated to Intrafix(®) SafeSet (n = 709) or normal infusion (n = 836) groups, matched for age, gender and preliminary diagnosis. Incidence of phlebitis was significantly higher using normal infusion apparatus compared with the Intrafix(®) SafeSet (23.4% versus 17.9%, respectively).
  
  
  CONCLUSIONS
  Intrafix(®) SafeSet infusion apparatus significantly reduced the incidence of phlebitis in patients in the neurological ICU, compared with normal infusion apparatus, and may be suitable for use in routine clinical practice.
authors: Neurological Intensive Care Unit, West China Hospital, Sichuan University, Chengdu, China.
authors: F
authors: F
authors: Liu
authors: D
authors: D
authors: Chen
authors: Y
authors: Y
authors: Liao
authors: L
authors: L
authors: Diao
authors: Y
authors: Y
authors: Liu
authors: M
authors: M
authors: Wu
authors: X
authors: X
authors: Xue
authors: C
authors: C
authors: You
authors: Y
authors: Y
authors: Kang
mesh_terms: D016022:Case-Control Studies; D002406:Catheterization, Peripheral / Q000009:adverse effects* / Q000295:instrumentation*; D005260:Female; D006801:Humans; D015994:Incidence; D007260:Infusion Pumps / Q000009:adverse effects; D007262:Infusions, Intravenous / Q000009:adverse effects*; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D010689:Phlebitis / Q000453:epidemiology* / Q000209:etiology