title: Myriberine A, a new alkaloid with an unprecedented heteropentacyclic skeleton from Myrioneuron faberi.
abstract: Myriberine A (1) possessing an unprecedented carbon skeleton was isolated from Myrioneuron faberi. The structure and absolute configuration of 1 were elucidated by a combination of spectroscopic data, X-ray crystallographic, and computational methods. Myriberine A (1) demonstrated inhibition against the hepatitis C virus (HCV) life cycle in vitro.
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, PR China.
authors: Sheng-Dian
authors: SD
authors: Huang
authors: Yu
authors: Y
authors: Zhang
authors: Ming-Ming
authors: MM
authors: Cao
authors: Ying-Tong
authors: YT
authors: Di
authors: Gui-Hua
authors: GH
authors: Tang
authors: Zong-Gen
authors: ZG
authors: Peng
authors: Jian-Dong
authors: JD
authors: Jiang
authors: Hong-Ping
authors: HP
authors: He
authors: Xiao-Jiang
authors: XJ
authors: Hao
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D018360:Crystallography, X-Ray; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D018922:HL-60 Cells; D016174:Hepacivirus / Q000187:drug effects; D006576:Heterocyclic Compounds, 4 or More Rings / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D019666:Rubiaceae / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D000998:Antiviral Agents; D004365:Drugs, Chinese Herbal; D006576:Heterocyclic Compounds, 4 or More Rings; C581421:myriberine A