title: Progressive intracranial fusiform aneurysms and T-cell immunodeficiency.
abstract: In the pediatric population, intracranial fusiform aneurysms have been associated with human immunodeficiency virus/acquired immunodeficiency syndrome and rarely with opportunistic infections related to other immunodeficiencies. The HIV virus and other infectious organisms have been implicated in the pathophysiology of these aneurysms. We present a child with T-cell immunodeficiency but no evidence of human immunodeficiency virus or opportunistic intracranial infections that developed progressive bilateral fusiform intracranial aneurysms. Our findings suggest a role of immunodeficiency or inflammation in the formation of some intracranial aneurysms.
authors: Department of Pediatrics, Section of Pediatric Neurology, University of Chicago Medical Center, Chicago, Illinois, USA.
authors: Juan A
authors: JA
authors: Piantino
authors: Fernando D
authors: FD
authors: Goldenberg
authors: Peter
authors: P
authors: Pytel
authors: Linda
authors: L
authors: Wagner-Weiner
authors: Sameer A
authors: SA
authors: Ansari
mesh_terms: D000293:Adolescent; D001921:Brain / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology*; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology*; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology*; D011859:Radiography