title: Severe methotrexate toxicity due to a concomitant administration of ciprofloxacin.
authors: A
authors: A
authors: Jarfaut
authors: R
authors: R
authors: Santucci
authors: D
authors: D
authors: Levêque
authors: R
authors: R
authors: Herbrecht
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000737:chemistry / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D001639:Bicarbonates / Q000009:adverse effects / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D002939:Ciprofloxacin / Q000009:adverse effects* / Q000737:chemistry / Q000627:therapeutic use; D003460:Crystallization; D003520:Cyclophosphamide / Q000008:administration & dosage; D003561:Cytarabine / Q000008:administration & dosage; D003967:Diarrhea / Q000139:chemically induced; D004317:Doxorubicin / Q000008:administration & dosage; D003875:Drug Eruptions / Q000209:etiology*; D004347:Drug Interactions; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D005440:Fluid Therapy; D016469:Fungemia / Q000150:complications / Q000188:drug therapy; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007069:Ifosfamide / Q000008:administration & dosage; D016393:Lymphoma, B-Cell / Q000188:drug therapy; D008479:Mediastinal Neoplasms / Q000188:drug therapy; D008657:Metabolic Clearance Rate / Q000187:drug effects; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects* / Q000097:blood / Q000493:pharmacokinetics; D052016:Mucositis / Q000139:chemically induced*; D010198:Pancytopenia / Q000139:chemically induced*; D011241:Prednisone / Q000008:administration & dosage; D012995:Solubility; D014556:Urine / Q000737:chemistry; D014751:Vindesine / Q000008:administration & dosage
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000998:Antiviral Agents; D001639:Bicarbonates; D003561:Cytarabine; D001761:Bleomycin; D002939:Ciprofloxacin; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D014751:Vindesine; D007069:Ifosfamide; D011241:Prednisone; D008727:Methotrexate