title: Synthesis of bisindolylmethanes and their cytotoxicity properties.
abstract: Polymer supported dichlorophosphate (PEG-OPOCl(2)) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compounds and their anti-cancer activity are evaluated.
authors: Department of Food Technology, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia. lasekan@food.upm.edu.my.
authors: Kalla Reddi Mohan
authors: KR
authors: Naidu
authors: Shaik Ibrahim
authors: SI
authors: Khalivulla
authors: Syed
authors: S
authors: Rasheed
authors: Sharida
authors: S
authors: Fakurazi
authors: Palanisamy
authors: P
authors: Arulselvan
authors: Ola
authors: O
authors: Lasekan
authors: Faridah
authors: F
authors: Abas
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D003603:Cytotoxins / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006367:HeLa Cells; D006801:Humans; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D003603:Cytotoxins; D007211:Indoles