title: Working memory and impulsivity predict marijuana-related problems among frequent users.
abstract: BACKGROUND
  Although marijuana is the most commonly used illicit substance in the US, only a small portion of users go on to develop dependence, suggesting that there are substantial individual differences in vulnerability to marijuana-related problems among users. Deficits in working memory and high trait impulsivity are two factors that may place marijuana users at increased risk for experiencing related problems.
  
  
  METHODS
  Using baseline data from an experimental study that recruited 104 frequent marijuana users (M=71.86% of prior 60 days, SD=22%), we examined the associations of working memory and trait impulsivity with marijuana-related problems.
  
  
  RESULTS
  Lower working memory, as measured by Trail Making Test B, but not short-term memory capacity, predicted more marijuana-related problems. Higher trait impulsivity scores were independently associated with greater number of problems.
  
  
  CONCLUSIONS
  Results suggest that marijuana users with reduced executive cognitive ability are more susceptible to developing problems related to their use. Trait impulsivity and executive working memory appear to be independent risk factors for experiencing marijuana-related problems.
authors: Center for Alcohol and Addiction Studies, Department of Behavioral and Social Sciences, Brown University, Providence, RI 02912, United States. anne_day@brown.edu
authors: Anne M
authors: AM
authors: Day
authors: Jane
authors: J
authors: Metrik
authors: Nichea S
authors: NS
authors: Spillane
authors: Christopher W
authors: CW
authors: Kahler
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007175:Impulsive Behavior / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology*; D008297:Male; D008385:Marijuana Smoking / Q000453:epidemiology* / Q000523:psychology*; D008570:Memory, Short-Term; D011237:Predictive Value of Tests; D055815:Young Adult