title: Two new diterpenoids from Excoecaria acerifolia.
abstract: A new tigliane diterpenoid, acerifolin A (1), and a new isopimarane diterpenoid, acerifolin B (2), together with two known compounds, were isolated from Excoecaria acerifolia. Their structures were elucidated on the basis of their spectroscopic methods, including 1D and 2D NMR techniques. All of the compounds were evaluated for cytotoxicity against five human cancer cell lines with cisplantin as a positive control.
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China.
authors: Xing-De
authors: XD
authors: Wu
authors: Lan-Chun
authors: LC
authors: Zhang
authors: Juan
authors: J
authors: He
authors: Gen-Tao
authors: GT
authors: Li
authors: Lin-Fen
authors: LF
authors: Ding
authors: Xiu
authors: X
authors: Gao
authors: Liao-Bin
authors: LB
authors: Dong
authors: Liu-Dong
authors: LD
authors: Song
authors: Yan
authors: Y
authors: Li
authors: Qin-Shi
authors: QS
authors: Zhao
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002945:Cisplatin / Q000494:pharmacology; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019665:Euphorbiaceae / Q000737:chemistry*; D005260:Female; D018922:HL-60 Cells; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes; D004365:Drugs, Chinese Herbal; C579836:acerifolin A; C579837:acerifolin B; D002945:Cisplatin