title: A new di-O-prenylated flavone from an actinomycete Streptomyces sp. MA-12.
abstract: A new di-O-prenylated flavone, named 7,3'-di-(γ,γ-dimethylallyloxy)-5-hydroxy-4'-methoxyflavone (1), was isolated from the culture broth of the endophytic actinomycete Streptomyces sp. MA-12 isolated from the root of the semi-mangrove plant Myoporum bontioides A. Gray. The structure of 1 was determined by comprehensive spectroscopic methods, including 1D and 2D NMR experiments (COSY, HMQC, and HMBC). Primary bioassays showed that 1 at concentration of 0.25 mM had moderate inhibitory activity against three plant pathogenic fungi including Colletotrichum musae, Gibberella zeae (Schweinitz) Petch, and Penicillium citrinum Thom.
authors: Institute of Biomaterial, College of Science, South China Agricultural University, Guangzhou 510642, China.
authors: Wei-Jia
authors: WJ
authors: Ding
authors: Sui-Qiang
authors: SQ
authors: Zhang
authors: Jin-Hua
authors: JH
authors: Wang
authors: Yue-Xia
authors: YX
authors: Lin
authors: Qiao-Xia
authors: QX
authors: Liang
authors: Wei-Jian
authors: WJ
authors: Zhao
authors: Chun-Yuan
authors: CY
authors: Li
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D047309:Flavones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D031643:Myoporum / Q000382:microbiology*; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000382:microbiology; D013302:Streptomyces / Q000737:chemistry*
chemical_list: C579750:7,3'-di-(gamma, gamma-dimethylallyloxy)-5-hydroxy-4'-methoxyflavone; D000935:Antifungal Agents; D047309:Flavones