title: Immunohistochemical detection of two neuronal populations involved in two different episodes of animal cognitive activity.
abstract: We developed a method to detect and superimpose neuronal populations involved in two different episodes of activity in the brain of single animal. This method is based on usage of two transcriptional factors with different accumulation curves, c-Fos and pCREB, as the markers. The overlap of neuronal populations involved in performance of spatial and nonspatial tasks in Morris water maze has been shown to occur at "chance" level.
authors: Laboratory of Neurobiology of Memory, P. K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia. chekhov_sergey@yahoo.co.uk
authors: S A
authors: SA
authors: Chekhov
authors: D V
authors: DV
authors: Bezriadnov
authors: O I
authors: OI
authors: Ivashkina
authors: E M
authors: EM
authors: Amelchenko
authors: K V
authors: KV
authors: Anokhin
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D015415:Biomarkers; D001921:Brain / Q000502:physiology*; D056547:CA1 Region, Hippocampal / Q000166:cytology; D056654:CA3 Region, Hippocampal / Q000166:cytology; D003071:Cognition / Q000502:physiology*; D017362:Cyclic AMP Response Element-Binding Protein / Q000235:genetics / Q000378:metabolism*; D007150:Immunohistochemistry; D008297:Male; D018782:Maze Learning / Q000502:physiology; D008568:Memory / Q000502:physiology; D051379:Mice; D008810:Mice, Inbred C57BL; D009474:Neurons / Q000502:physiology*; D016760:Proto-Oncogene Proteins c-fos / Q000235:genetics / Q000378:metabolism*; D013028:Space Perception / Q000502:physiology; D014158:Transcription, Genetic
chemical_list: D015415:Biomarkers; C492004:Creb1 protein, mouse; D017362:Cyclic AMP Response Element-Binding Protein; D016760:Proto-Oncogene Proteins c-fos