title: Profix cemented total knee replacement: a 5-year outcome review from Lagos, Nigeria.
abstract: BACKGROUND
  Total knee replacement is a standard treatment for severe osteoarthritis of the knees. It is however, still a novel procedure in Nigeria. Literature on the procedure and outcome of management are sparse in Nigeria.
  
  
  OBJECTIVE
  This study aimed at describing Total Knee prosthetic Replacement as it is practiced in National Orthopaedic Hospital, Lagos.
  
  
  METHODS
  Data on patients treated with Total knee replacement between 2006 and 2010 were analyzed retrospectively. The standard anterior approach, with a medial parapatellar incision under pneumatic tourniquet was used in all cases.
  
  
  RESULTS
  There were a total of 59 knees in 48 patients operated, with a female: male ratio of 5:1. Patients were in the sixth to ninth decades of life. There was a statistically significant relationship between duration of symptoms and severity of angular deformity. The average pre-operative Knee score (KS) was 27 and average function score (FS) was 43. Average duration of surgery was 126.38 minutes. Tourniquet removal after wound closure was associated with reduced intra-operative blood loss (p < 0.05). Post-operative complications included peri-prosthetic fracture (1.69%), post-operative anaemia (8.47%), superficial wound dehiscence (3.39%) and foot drop (3.39%). The mean post-operative KS and FS increased to 80 and 75 respectively.
  
  
  CONCLUSIONS
  Total knee replacement, though a novel procedure in our institution is beneficial to patients with severe osteoarthritis. A long term outcome study is being planned.
authors: Arthroplasty Unit, National Orthopaedic Hospital, Igbobi PMB 2009, Yaba, Lagos State.
authors: M E
authors: ME
authors: Ugbeye
authors: O O
authors: OO
authors: Odunubi
authors: E M
authors: EM
authors: Dim
authors: O O
authors: OO
authors: Ekundayo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D016063:Blood Loss, Surgical; D001843:Bone Cements; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009549:Nigeria; D061646:Operative Time; D010003:Osteoarthritis / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications; D020127:Recovery of Function; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D001843:Bone Cements