title: Regenerative medicine in 2012: the coming of age of musculoskeletal tissue engineering.
abstract: Tissue engineering and regenerative medicine have advanced rapidly towards the development of therapeutic solutions for musculoskeletal disorders. In 2012, breakthroughs have been made in the guidance of adult stem cell homing, the tissue regenerative activity of stem-cell-derived extracellular matrix has been tested, and novel, mechanically superior biomaterials have been fabricated.
authors: Department of Orthopaedic Surgery, Center for Cellular and Molecular Engineering, University of Pittsburgh School of Medicine, 450 Technology Drive, Room 221, Pittsburgh, PA 15219, USA. rst13@pitt.edu
authors: Rocky S
authors: RS
authors: Tuan
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D005109:Extracellular Matrix / Q000502:physiology; D006801:Humans; D020100:Hydrogels; D059630:Mesenchymal Stem Cells / Q000502:physiology; D051379:Mice; D009140:Musculoskeletal Diseases / Q000628:therapy*; D044968:Regenerative Medicine / Q000379:methods / Q000639:trends*; D023822:Tissue Engineering / Q000379:methods / Q000639:trends*; D054457:Tissue Scaffolds / Q000639:trends*
chemical_list: D020100:Hydrogels