title: In vitro antifungal susceptibility of clinically relevant species belonging to Aspergillus section Flavi.
abstract: The in vitro antifungal susceptibility of 77 isolates belonging to different clinically relevant species of Aspergillus section Flavi, including those of different phylogenetic clades of A. flavus, was tested for nine antifungal agents using a microdilution reference method (CLSI, M38-A2). Terbinafine and the echinocandins demonstrated lower MICs/MECs for all species evaluated, followed by posaconazole. Amphotericin B showed MICs ≥ 2 μg/ml for 38 (49.4%) of the 77 isolates tested.
authors: Special Mycology Laboratory-LEMI, Department of Medicine, Federal University of São Paulo, São Paulo, Brazil.
authors: Sarah S
authors: SS
authors: Gonçalves
authors: Alberto M
authors: AM
authors: Stchigel
authors: Josep
authors: J
authors: Cano
authors: Josep
authors: J
authors: Guarro
authors: Arnaldo L
authors: AL
authors: Colombo
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology*; D001230:Aspergillus / Q000187:drug effects*; D054714:Echinocandins / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009281:Naphthalenes / Q000494:pharmacology; D010802:Phylogeny; D000077291:Terbinafine; D014230:Triazoles / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D009281:Naphthalenes; D014230:Triazoles; C101425:posaconazole; D000666:Amphotericin B; D000077291:Terbinafine