title: Effect of coenzyme Q10 on proteomic profile of blood plasma and cytosolic and microsomal fractions of rat hepatocytes during ontogeny.
abstract: The proteomic features of blood plasma and subcellular fractions of rat hepatocytes were studied during long-term dietary consumption of coenzyme Q10 as the endogenous mediator of antioxidant and energy homeostasis in the cell. Long-term coenzyme Q10 consumption was followed by the formation of specific nutriproteomes of the microsomal and cytosolic fractions of rat hepatocytes.
authors: Institute of Nutrition, Russian Academy of Medical Sciences; Center of Collective Use Human Proteome, V. N. Orekhovich Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, Russia. sharanova.natalia@gmail.com
authors: N E
authors: NE
authors: Sharanova
authors: I Yu
authors: IY
authors: Toropygin
authors: E V
authors: EV
authors: Khriapova
authors: A V
authors: AV
authors: Vasilyev
authors: M M G
authors: MM
authors: Gapparov
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology; D003600:Cytosol; D022781:Hepatocytes / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D008861:Microsomes / Q000187:drug effects / Q000378:metabolism; D010949:Plasma / Q000187:drug effects* / Q000502:physiology; D020543:Proteome / Q000378:metabolism*; D040901:Proteomics; D051381:Rats; D017208:Rats, Wistar; D013347:Subcellular Fractions / Q000378:metabolism; D014451:Ubiquinone / Q000008:administration & dosage / Q000031:analogs & derivatives*
chemical_list: D000975:Antioxidants; D020543:Proteome; D014451:Ubiquinone; C024989:coenzyme Q10