title: Efficient synthesis of silylated 2,2-difluorostyrene derivatives through Suzuki-Miyaura cross-coupling of 2,2-difluoro-1-iodo-1-silylethenes.
abstract: We report a new synthetic sequence for the preparation of silylated 2,2-difluorostyrene derivatives. This new route has numerous advantages over the previous one including enhanced scope, higher yields, ease of purification, and significant reduction of the amount of desilylated side-products. An unexpected transformation of a silylated 2,2-difluorostyrene derivative is also presented.
authors: Canada Research Chair in Organic and Medicinal Chemistry, Department of Chemistry, 1045 avenue de la Médecine, Université Laval, Québec, Canada.
authors: Marc-Olivier
authors: MO
authors: Turcotte-Savard
authors: Jean-François
authors: JF
authors: Paquin
mesh_terms: D015394:Molecular Structure; D013343:Styrenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D013343:Styrenes