title: Early detection biomarkers for ovarian cancer.
abstract: Despite the widespread use of conventional and contemporary methods to detect ovarian cancer development, ovarian cancer remains a common and commonly fatal gynecological malignancy. The identification and validation of early detection biomarkers highly specific to ovarian cancer, which would permit development of minimally invasive screening methods for detecting early onset of the disease, are urgently needed. Current practices for early detection of ovarian cancer include transvaginal ultrasonography, biomarker analysis, or a combination of both. In this paper we review recent research on novel and robust biomarkers for early detection of ovarian cancer and provide specific details on their contributions to tumorigenesis. Promising biomarkers for early detection of ovarian cancer include KLK6/7, GSTT1, PRSS8, FOLR1, ALDH1, and miRNAs.
authors: The Genomics and Biomarker Program, The John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ 07601, USA.
authors: Sreeja
authors: S
authors: Sarojini
authors: Ayala
authors: A
authors: Tamir
authors: Heejin
authors: H
authors: Lim
authors: Shihong
authors: S
authors: Li
authors: Shifang
authors: S
authors: Zhang
authors: Andre
authors: A
authors: Goy
authors: Andrew
authors: A
authors: Pecora
authors: K Stephen
authors: KS
authors: Suh