title: Possible aspects of using cultured stem cell of laboratory primates in experimental medicine.
abstract: We describe the methods of isolation and culturing of mesenchymal stem cells from 3 monkey species Macaca mulatta, Papio hamadryas, and Macaca fascicularis. Flow cytofluorometry showed that the cells do not express CD34, CD45, and HLA-DR, but most of them (78-98%) express CD90 marker. The cardioprotective effects of cultured mesenchymal stem cells in cardiomyopathy induced by administration of antitumor anthracycline drugs (doxorubicin).
authors: Research Institute of Medical Primatology, Russian Academy of Medical Sciences, Sochi, Russia. agrba_vz@mail.ru
authors: V Z
authors: VZ
authors: Agrba
authors: V A
authors: VA
authors: Porkhanov
authors: A G
authors: AG
authors: Konoplyannikov
authors: S Sh
authors: SSh
authors: Kal'sina
authors: D D
authors: DD
authors: Karal-ogly
authors: I E
authors: IE
authors: Ignatova
authors: T E
authors: TE
authors: Gvozdik
authors: A A
authors: AA
authors: Agumava
authors: A V
authors: AV
authors: Leontiuk
authors: B A
authors: BA
authors: Lapin
mesh_terms: D000818:Animals; D018952:Antigens, CD34 / Q000378:metabolism; D001374:Azacitidine; D009202:Cardiomyopathies / Q000139:chemically induced / Q000517:prevention & control* / Q000628:therapy*; D018929:Cell Culture Techniques; D002454:Cell Differentiation; D002469:Cell Separation; D002478:Cells, Cultured; D004317:Doxorubicin; D006684:HLA-DR Antigens / Q000378:metabolism; D017493:Leukocyte Common Antigens / Q000378:metabolism; D008251:Macaca; D008252:Macaca fascicularis; D008253:Macaca mulatta; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000378:metabolism; D048529:Papio hamadryas; D018800:Thy-1 Antigens / Q000378:metabolism
chemical_list: D018952:Antigens, CD34; D006684:HLA-DR Antigens; D018800:Thy-1 Antigens; D004317:Doxorubicin; D017493:Leukocyte Common Antigens; D001374:Azacitidine