title: Rapid progressive bilateral hearing loss due to granulomatous otitis media in Lyme disease.
abstract: We report on a patient with Lyme disease who presented with chronic bilateral otitis media and cranial neuropathy with rapid progressive hearing loss. After ceftriaxone and high-dose intravenous immunoglobulins, the disease was controlled only with methylprednisolone and cyclophosphamide. The relationship between Lyme disease and granulomatous vasculitis is discussed. Lyme disease should be kept in mind in the differential diagnosis of various otolaryngological and neurological presentations.
authors: Otorhinolaryngology Department, Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, 13 Emil Isac, Cluj-Napoca, Romania. almacjro@yahoo.com
authors: Alma
authors: A
authors: Maniu
authors: Laura
authors: L
authors: Damian
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D002908:Chronic Disease; D003389:Cranial Nerve Diseases / Q000150:complications; D003520:Cyclophosphamide / Q000008:administration & dosage; D018450:Disease Progression; D017809:Fatal Outcome; D006099:Granuloma / Q000150:complications*; D006312:Hearing Loss, Bilateral / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008193:Lyme Disease / Q000150:complications*; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D010033:Otitis Media / Q000150:complications*; D038781:Otoscopy; D018058:Tympanic Membrane Perforation / Q000150:complications; D014657:Vasculitis / Q000150:complications
chemical_list: D000893:Anti-Inflammatory Agents; D003520:Cyclophosphamide; D008775:Methylprednisolone