title: Factors affecting response of chemotherapy in women with ovarian cancer.
abstract: Chemotherapy plays an important role in the treatment of ovarian cancer. Patients' response to chemotherapy is determined by a variety of acknowledged factors, but one might expect that many of them are yet to be described. The aim of this paper was to present the most essential yet still to be generally assessed in clinical practice, factors, which include: E-cadhedrin, hypoxia inducible factor alpha, survivin, COX-2, clusterin, BRCA1 protein, TP53 protein, YY1 protein, multidrug resistance protein, and interleukin-8.
authors: Clinic of Oncology in Poznań, Departament of Gynecology, Poznań, Poland. jola.lubin@gmail.com
authors: J
authors: J
authors: Lubin
authors: A
authors: A
authors: Markowska
authors: P
authors: P
authors: Knapp
mesh_terms: D018435:ATP Binding Cassette Transporter, Subfamily B; D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000502:physiology; D015820:Cadherins / Q000032:analysis / Q000502:physiology; D051152:Clusterin / Q000032:analysis; D051546:Cyclooxygenase 2 / Q000032:analysis / Q000502:physiology; D005260:Female; D019398:Genes, BRCA1; D016158:Genes, p53; D006801:Humans; D051795:Hypoxia-Inducible Factor 1, alpha Subunit / Q000032:analysis / Q000502:physiology; D051034:Inhibitor of Apoptosis Proteins / Q000032:analysis / Q000502:physiology; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000235:genetics; D000077022:Survivin
chemical_list: C513055:ABCB1 protein, human; D018435:ATP Binding Cassette Transporter, Subfamily B; D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; C107489:BIRC5 protein, human; C495242:CLU protein, human; D015820:Cadherins; D051152:Clusterin; C497442:HIF1A protein, human; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D051034:Inhibitor of Apoptosis Proteins; D000077022:Survivin; D051546:Cyclooxygenase 2