title: Flavonoids profiles, antioxidant, acetylcholinesterase inhibition activities of extract from Dryoathyrium boryanum (Willd.) Ching.
abstract: The profiles and bioactivities of flavonoids extracted from Dryoathyrium boryanum (Willd.) Ching were investigated. The total flavonoids content in extract from D. boryanum is about 145.8mg/g. By means of HPLC-DAD-ESI-MS, the main flavonoids in D. boryanum were tentatively identified as 3-hydroxyphloretin 6'-O-hexoside, quercetin-7-hexoside, apigenin7-O-glucoside, luteolin 7-O-glucoside, apigenin 7-O-galactoside, acacetin 7-O-(α-D-apio-furanosyl) (1→6)-β-d-glucoside, 3-hydroxy phloretin 6-O-hexoside, luteolin-6-C-glucoside. 0.21mg/ml flavonoids extract from D. boryanum showed very strong superoxide anion radical scavenging potential, which is higher than that of rutin (0.25mg/ml). The extract (0.21mg/ml of flavonoids) from D. boryanum exhibited similar DPPH scavenging potential with that of rutin (0.25mg/ml). However, rutin (0.25mg/ml) showed a significantly higher reducing power and ABTS scavenging potential than that of 0.21mg/ml flavonoids extract from D. boryanum. It had no effect on acetylcholinesterase. D. boryanum can be considered as a medicinal plant and the flavonoids from D. boryanum are excellent antioxidants.
authors: Department of Biology, Shanghai Normal University, 100 Guilin Rd., Shanghai 200234, PR China.
authors: Jianguo
authors: J
authors: Cao
authors: Xian
authors: X
authors: Xia
authors: Xiling
authors: X
authors: Dai
authors: Jianbo
authors: J
authors: Xiao
authors: Quanxi
authors: Q
authors: Wang
authors: K
authors: K
authors: Andrae-Marobela
authors: H
authors: H
authors: Okatch
mesh_terms: D000110:Acetylcholinesterase / Q000187:drug effects*; D000975:Antioxidants / Q000494:pharmacology*; D002800:Cholinesterase Inhibitors / Q000494:pharmacology*; D002851:Chromatography, High Pressure Liquid; D029624:Ferns / Q000737:chemistry*; D005419:Flavonoids / Q000302:isolation & purification* / Q000494:pharmacology; D010936:Plant Extracts / Q000302:isolation & purification* / Q000494:pharmacology; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D000975:Antioxidants; D002800:Cholinesterase Inhibitors; D005419:Flavonoids; D010936:Plant Extracts; D000110:Acetylcholinesterase