title: Hemodynamic analysis of vascular stenting treatment outcome: computational fluid dynamics method vs optical flow method.
abstract: OBJECTIVE
  Computational fluid dynamics method (CFDM) and optical flow method (OFM) effectively provide the hemodynamic information based on the digital subtraction angiogram (DSA). However, the quantitative analysis in comparison of CFDM and OFM is still absent. The goal of this study is to apply CFDM and OFM in quantitative analysis of stenting treatment.
  
  
  METHODS
  A left carotid stenosis patient underwent stenting of percutaneous transluminal angioplasty was analyzed as an example. CFDM and OFM for hemodynamic analysis on digital subtraction angiography before and after stenting treatment were presented.
  
  
  RESULTS
  Improvement gains of blood flow velocities on left internal carotid artery after stenting treatment for different initial conditions on the common carotid artery were 1.91 ∼ 2.13, 1.62 ∼ 2.09, and 0.69 by CFDM with Newtonian and non-Newtonian fluids and OFM, respectively. With the CFDM analysis, the flow mapping by OFM using time resolved DSA data on the fly to estimate hemodynamic significance of a cervical carotid stenosis was explained.
  
  
  CONCLUSIONS
  Quantificative blood flow estimations by CFDM and OFM to evaluate the treatment outcomes to patient with carotid stenosis are practical. Both methods are able to provide quantitative information of blood flow for stenting treatment. It is advantagious to use both methods in treatment evaluation.
authors: Department of Biomedical Imaging and Radiological Science, China Medical University, Taiwan, China.
authors: Tzu-Ching
authors: TC
authors: Shih
authors: Yang-Hsien
authors: YH
authors: Lin
authors: Yung-Jen
authors: YJ
authors: Ho
authors: Hung-Da
authors: HD
authors: Hsiao
authors: Yung-Hui
authors: YH
authors: Huang
authors: Tzung-Chi
authors: TC
authors: Huang
mesh_terms: D000465:Algorithms; D015901:Angiography, Digital Subtraction / Q000379:methods*; D017130:Angioplasty; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000601:surgery; D016893:Carotid Stenosis / Q000000981:diagnostic imaging* / Q000601:surgery*; D003198:Computer Simulation; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008875:Middle Aged; D012039:Regional Blood Flow; D015607:Stents; D016896:Treatment Outcome