title: Quantification of the human cerebrovasculature: a 7Tesla and 320-row CT in vivo study.
abstract: OBJECTIVE
  Human cerebrovasculature has not been quantified in volume, length, and vascular-brain relationships. We investigated this using imaging.
  
  
  METHODS
  From 0.5-mm 7T and 320-row CT acquisitions, 6 arterial and 4 venous systems were reconstructed, measured, and analyzed.
  
  
  RESULTS
  The ratio of the volume of arterial to venous system is approximately 1:3. The ratio of the volume of dural sinuses to vasculature is 1:2. The ratio of the posterior (PCA) to anterior (ACA) to middle cerebral artery (MCA) is 1:2:4 in volume and length. Ratios of left to right vessels are 1:1 for arteries and veins. Ratios of branching frequency for the ACA, MCA, and PCA are 1:1:1. The branching frequency ratio for superficial to deep veins is 1:2. The MCA occupies 1/2 of arterial length and 1/4 of vascular length. The ratio of the length of superficial to deep veins is 1:1 and each is equal to 1/4 of the vascular length. The ratio of cerebrovasculature to brain volume is 2.5%.
  
  
  CONCLUSIONS
  Despite its enormous complexity, cerebrovasculature is characterized by 4 approximate proportions, 1:1, 1:2, 1:3, 1:4, and their combinations, 1:1:1 and 1:2:4.
authors: Biomedical Imaging Lab, Agency for Science Technology and Research, Singapore. wieslaw@sbic.a-star.edu.sg
authors: Wieslaw Lucjan
authors: WL
authors: Nowinski
authors: Fiftarina
authors: F
authors: Puspitasari
authors: Ihar
authors: I
authors: Volkau
authors: William W
authors: WW
authors: Orrison
authors: Michael V
authors: MV
authors: Knopp
mesh_terms: D000328:Adult; D000368:Aged; D001921:Brain / Q000098:blood supply*; D002533:Cerebral Angiography / Q000379:methods*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods*