title: Computational quantification of the cardiac energy consumption during intra-aortic balloon pumping using a cardiac electromechanics model.
abstract: To quantify the reduction in workload during intra-aortic balloon pump (IABP) therapy, indirect parameters are used, such as the mean arterial pressure during diastole, product of heart rate and peak systolic pressure, and pressure-volume area. Therefore, we investigated the cardiac energy consumption during IABP therapy using a cardiac electromechanics model. We incorporated an IABP function into a previously developed electromechanical model of the ventricle with a lumped model of the circulatory system and investigated the cardiac energy consumption at different IABP inflation volumes. When the IABP was used at inflation level 5, the cardiac output and stroke volume increased 11%, the ejection fraction increased 21%, the stroke work decreased 1%, the mean arterial pressure increased 10%, and the ATP consumption decreased 12%. These results show that although the ATP consumption is decreased significantly, stroke work is decreased only slightly, which indicates that the IABP helps the failed ventricle to pump blood efficiently.
authors: Department of Medical IT Convergence Engineering, Kumoh National Institute of Technology, Gumi, Korea.
authors: Ki Moo
authors: KM
authors: Lim
authors: Jeong Sang
authors: JS
authors: Lee
authors: Min-Soo
authors: MS
authors: Gyeong
authors: Jae-Sung
authors: JS
authors: Choi
authors: Seong Wook
authors: SW
authors: Choi
authors: Eun Bo
authors: EB
authors: Shim
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism*; D062186:Arterial Pressure; D002302:Cardiac Output; D006333:Heart Failure / Q000473:pathology; D006339:Heart Rate; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D008962:Models, Theoretical; D013318:Stroke Volume; D016277:Ventricular Function, Left
chemical_list: D000255:Adenosine Triphosphate
keywords: ATP Consumption; Cardiac Electromechanics Model; Intra-Aortic Balloon Pump; Stroke Work