title: [Value of fractional nitric oxide concentration in exhaled breath in assessing level of asthma control in children].
abstract: OBJECTIVE
  To investigate the value of fractional nitric oxide concentration in exhaled breath (FeNO) in assessing the level of asthma control in children.
  
  
  METHODS
  A total of 226 asthmatic children were divided into controlled asthma (n= 86), partially controlled asthma (n=63), and uncontrolled asthma groups (n=77). Ninety healthy children were enrolled as controls. FeNO was measured for both asthmatic and healthy children using the Swedish-designed NIOX system.
  
  
  RESULTS
  The control group had an FeNO of 14±6 ppb, the controlled asthma group had an FeNO of 29±26 ppb, the partially controlled asthma group had an FeNO of 32±30 ppb, and the uncontrolled asthma group had an FeNO of 40±32 ppb. The three asthma groups showed significantly higher FeNO than the control group (P<0.05). The uncontrolled asthma group showed significantly higher FeNO than the controlled asthma group (P<0.05), but there were no significant differences in FeNO between the partially controlled and uncontrolled asthma groups and between the partially controlled and controlled asthma groups (P>0.05).
  
  
  CONCLUSIONS
  Asthmatic children have significantly higher FeNO than healthy children, and FeNO is correlated with the level of asthma control.
authors: Capital Medical University, Beijing, China. drxiangli@163.com
authors: Li
authors: L
authors: Xiang
authors: Ya-Nan
authors: YN
authors: Fu
authors: Zhen
authors: Z
authors: Li
authors: Yi-Xin
authors: YX
authors: Ren
authors: Xiao-Chun
authors: XC
authors: Rao
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D001944:Breath Tests; D002648:Child; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D009569:Nitric Oxide / Q000032:analysis*
chemical_list: D009569:Nitric Oxide