title: Polyhedral oligomeric silsesquioxanes as functional monomer to prepare hybrid monolithic columns for capillary electrochromatography and capillary liquid chromatography.
abstract: A simple approach to fabricate hybrid monolithic column within the confines of fused-silica capillaries (75 μm i.d.) was introduced. A polyhedral oligomeric silsesquioxanes (POSS) reagent containing a methacrylate group was selected as functional monomer, and copolymerized with bisphenol A dimethacrylate (BPADMA) or ethylene dimethacrylate (EDMA) in the presence of porogenic solvents via thermally initiated free radical polymerization. After optimization of the preparation conditions, two POSS-containing hybrid monoliths were successfully prepared and exhibited good permeability and stability. By comparison of the separation efficiencies of the resulting poly(POSS-co-BPADMA) and poly(POSS-co-EDMA) monoliths in capillary electrochromatography (CEC) and capillary liquid chromatography (cLC), it was indicated the former has better column efficiencies for alkylbenzenes, phenols, anilines and PAHs in CEC and cLC than the latter. Particularly, the hybrid poly(POSS-co-BPADMA) monolith is more suitable for separation of PAHs due to π-π interaction between the analytes and aromatic rings in the surface of monolithic stationary phase.
authors: CAS Key Laboratory of Separation Science for Analytical Chemistry, National Chromatographic R & A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Dalian 116023, China. junjieou@dicp.ac.cn
authors: Junjie
authors: J
authors: Ou
authors: Zhenbin
authors: Z
authors: Zhang
authors: Hui
authors: H
authors: Lin
authors: Jing
authors: J
authors: Dong
authors: Hanfa
authors: H
authors: Zou
mesh_terms: D000814:Aniline Compounds / Q000302:isolation & purification; D001555:Benzene Derivatives / Q000302:isolation & purification; D001559:Benzhydryl Compounds / Q000737:chemistry*; D053801:Capillary Electrochromatography / Q000295:instrumentation*; D008689:Methacrylates / Q000737:chemistry*; D017646:Organosilicon Compounds / Q000737:chemistry*; D010636:Phenols / Q000302:isolation & purification; D011084:Polycyclic Aromatic Hydrocarbons / Q000302:isolation & purification; D058105:Polymerization; D000098826:Bisphenol A Compounds
chemical_list: D000814:Aniline Compounds; D001555:Benzene Derivatives; D001559:Benzhydryl Compounds; D008689:Methacrylates; D017646:Organosilicon Compounds; D010636:Phenols; D011084:Polycyclic Aromatic Hydrocarbons; C521417:polyhedraloligosilsesquioxane; C004919:ethylene dimethacrylate; C002462:4,4'-isopropylidenediphenol dimethacrylate; D000098826:Bisphenol A Compounds