title: The hidden quality gap in discovery.
abstract: Progress made through technological advances in drug discovery can be undermined by problems with measurement equipment, but it is often difficult to detect the issues without a specific investigation. This article describes the fundamentals of measurement systems analysis and focuses on the issue of precision. Three case studies are given where measurement systems were found to be flawed when subjected to a systematic analysis, and examples of the approaches needed for correction are described.
authors: SSA & Company Management Consultants, Berkeley Square House, Berkeley Square, London W1J 6BD, UK. dhampton@ssaandco.com
authors: David
authors: D
authors: Hampton
authors: Toby
authors: T
authors: Winchester
authors: Pauline
authors: P
authors: Carnell
authors: Jerry
authors: J
authors: Lanfear
mesh_terms: D055808:Drug Discovery; D011786:Quality Control; D012106:Research