title: Job insecurity and incident coronary heart disease: the Whitehall II prospective cohort study.
abstract: OBJECTIVE
  This study uses a prospective design to examine the association between self-reported job insecurity and incident coronary heart disease; an association which has been little investigated previously.
  
  
  METHODS
  Participants were 4174 British civil servants (1236 women and 2938 men), aged 42 to 56 with self-reported data on job insecurity and free from coronary heart disease at baseline (1995-6). These participants were followed until 2002-4, an average of 8.6 years, for incident fatal coronary heart disease, clinically verified incident non-fatal myocardial infarction, or definite angina (a total of 168 events).
  
  
  RESULTS
  Cox proportional hazard models adjusted for socio-demographic characteristics showed job insecurity to be associated with a 1.42-fold (95% CI, 1.05-1.93) risk of incident coronary heart disease compared with secure employment. Adjustment for physiological and behavioral cardiovascular risk factors had little effect on this estimate; 1.38 (1.01-1.88).
  
  
  CONCLUSIONS
  This study suggests that job insecurity may adversely affect coronary health.
authors: School of Social and Community Medicine, University of Bristol, UK. jane.ferrie@ucl.ac.uk
authors: Jane E
authors: JE
authors: Ferrie
authors: Mika
authors: M
authors: Kivimäki
authors: Martin J
authors: MJ
authors: Shipley
authors: George
authors: G
authors: Davey Smith
authors: Marianna
authors: M
authors: Virtanen
mesh_terms: D000328:Adult; D000787:Angina Pectoris / Q000453:epidemiology; D003327:Coronary Disease / Q000453:epidemiology*; D004651:Employment; D005260:Female; D006801:Humans; D015994:Incidence; D008131:London / Q000453:epidemiology; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology; D016016:Proportional Hazards Models; D012307:Risk Factors; D013315:Stress, Psychological / Q000150:complications*