title: Three new steroid glycosides from the starfish Asterina pectinifera.
abstract: Three new steroid glycosides, pectiniosides H-J (1-3), were isolated along with three known compounds (4-6) including a steroid glycoside and two polyhydroxysteroids, from the alcoholic extract of the starfish Asterina pectinifera. The structures of 1-3 were determined by extensive NMR and HR-ESI-MS experiments. Compounds 1-4 did not show cytostatic activity on HL-60 cells below 100 μM, while compounds 5-6 showed moderate cytostatic activity, with IG50 values of 80.3 and 40.5 μM, respectively.
authors: a School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University , Shenyang , 110016 , P.R. China.
authors: Zhanqiang
authors: Z
authors: Li
authors: Gang
authors: G
authors: Chen
authors: Xuan
authors: X
authors: Lu
authors: Haifeng
authors: H
authors: Wang
authors: Baomin
authors: B
authors: Feng
authors: Yuehu
authors: Y
authors: Pei
mesh_terms: D000818:Animals; D045424:Complex Mixtures / Q000032:analysis*; D000431:Ethanol; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D013215:Starfish / Q000737:chemistry*; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D045424:Complex Mixtures; D006027:Glycosides; D013256:Steroids; D000431:Ethanol