title: Transcatheter valve-in-valve therapies: patient selection, prosthesis assessment and selection, results, and future directions.
abstract: The development of transcatheter valve implantations (TAVI) has induced profound changes in the treatment of valvular heart disease over the past decade. At the same time, due to excellent clinical results, bioprostheses continuously outperformed mechanical prostheses. The increasing number of elderly patients has led to numerous patients presenting with deteriorated bioprostheses needing reoperation. In selected high-risk patients or patients with unreasonable surgical risk, valve-in-valve TAVI has advanced to a viable alternative to conventional redo surgery. High procedural success, good hemodynamics and acceptable clinical results were reported up until now. Valve-in-valve TAVI seems to be safe and effective in treatment of deteriorated valve prostheses in high-risk patients. The valve-in-valve concept presents the next step toward an individual treatment strategy for patients at prohibitive risk for conventional surgery. Present studies were reviewed with special concern to patient selection, prosthesis assessment, device selection, clinical outcome and technical challenging aspects as well.
authors: Department of Cardiac Surgery, University Heart Center Dresden, Fetscherstrasse 76, Dresden, Germany. manuel.wilbring@gmail.com
authors: Manuel
authors: M
authors: Wilbring
authors: Konstantin
authors: K
authors: Alexiou
authors: Sems-Malte
authors: SM
authors: Tugtekin
authors: Bjoern
authors: B
authors: Sill
authors: Gregor
authors: G
authors: Simonis
authors: Klaus
authors: K
authors: Matschke
authors: Utz
authors: U
authors: Kappert
mesh_terms: D001705:Bioprosthesis; D006328:Cardiac Catheterization / Q000379:methods; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000379:methods* / Q000639:trends; D006801:Humans; D018579:Patient Selection; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012086:Reoperation / Q000379:methods / Q000639:trends