title: Bleeding complications after central line insertions: relevance of pre-procedure coagulation tests and institutional transfusion policy.
abstract: BACKGROUND
  The aim of this study was to map pre-procedural variables for insertion of a central venous catheter, prophylactic blood component use and to investigate whether any independent variable could be identified as an independent risk factor for associated bleeding complications in patients outside the intensive care unit.
  
  
  METHODS
  In this retrospective study, we investigated 1737 consecutive insertions of central venous catheters in 1444 patients in a large university hospital during 2009-2010. Pre-procedural coagulation status, blood component use, type of catheter, insertion site and complications during insertion were recorded and compared with bleeding complications documented on electronic charts.
  
  
  RESULTS
  No serious bleeding complications were recorded in connection with the insertion of central venous catheters. Sixteen of 1769 (0.9%) insertions caused grade 2 bleeding, defined as bleeding requiring prolonged compression at the insertion site. Insertion of a large bore central dialysis catheter was found to be an independent risk factor for bleeding complications. Neither conventional coagulation tests nor accidental arterial puncture or the number of needle passes could predict bleeding complications in this study.
  
  
  CONCLUSIONS
  This retrospective study, in non-ICU patients, shows that serious bleeding complications in association with central line insertions are uncommon and that insertion of a large bore catheter is likely to be an independent risk factor for mild-bleeding complications in this population.
authors: Department of Intensive and Perioperative Care, Skane University Hospital and Lund University, Lund, Sweden. thomas.kander@skane.se
authors: T
authors: T
authors: Kander
authors: A
authors: A
authors: Frigyesi
authors: J
authors: J
authors: Kjeldsen-Kragh
authors: H
authors: H
authors: Karlsson
authors: F
authors: F
authors: Rolander
authors: U
authors: U
authors: Schött
mesh_terms: D001777:Blood Coagulation; D001780:Blood Coagulation Tests / Q000379:methods; D001803:Blood Transfusion / Q000379:methods*; D002405:Catheterization, Central Venous / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods; D057785:Catheters / Q000009:adverse effects; D006470:Hemorrhage; D006785:Hospitals, University; D006801:Humans; D016134:Organizational Policy; D012189:Retrospective Studies; D012307:Risk Factors