title: Collagen hemostat significantly reduces time to hemostasis compared with cellulose: COBBANA, a single-center, randomized trial.
abstract: BACKGROUND
  This single-center, randomized trial compares the hemostatic effectiveness of microfibrillar collagen and oxidized cellulose in arterial bypass surgery.
  
  
  METHODS
  In patients undergoing arterial bypass surgery, 2 hemostats, microfibrillar collagen and oxidized cellulose, were randomly used to achieve hemostasis. The primary endpoint was the time to hemostasis. The secondary endpoints were the complication rate, mortality, number of hemostats required, handling, and adhesion.
  
  
  RESULTS
  Collagen achieved hemostasis significantly faster than cellulose, with considerably less hemostats. In addition, its ease of use was rated substantially better.
  
  
  CONCLUSIONS
  In arterial bypass surgery, microfibrillar collagen is more effective than oxidized cellulose in achieving hemostasis.
authors: Department of Vascular Surgery, Klinikum Hanau GmbH, Hanau, Germany.
authors: Bekim
authors: B
authors: Qerimi
authors: Petra
authors: P
authors: Baumann
authors: Johannes
authors: J
authors: Hüsing
authors: Hanns-Peter
authors: HP
authors: Knaebel
authors: Hardy
authors: H
authors: Schumacher
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical; D019917:Blood Vessel Prosthesis Implantation; D002483:Cellulose, Oxidized; D003094:Collagen; D005260:Female; D006488:Hemostasis, Surgical; D006490:Hemostatics; D006801:Humans; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000601:surgery; D011138:Polytetrafluoroethylene; D013997:Time Factors
chemical_list: D002483:Cellulose, Oxidized; D006490:Hemostatics; D011138:Polytetrafluoroethylene; D003094:Collagen