title: Plasmacytoma of the larynx.
abstract: Amyloid is an extracellular proteinaceous low-molecular-weight fibril. In the larynx, amyloid deposits usually represent a benign localized disease. Although laryngeal amyloidosis is an indolent lesion, amyloid deposition in the larynx may actually result from a lymphoproliferative disorder and not isolated amyloidosis. In this case report, we describe a patient referred for laryngeal amyloidosis who was subsequently diagnosed with extramedullary plasmacytoma of the larynx. The report discusses the presentation, diagnosis, and treatment provided. The importance of systemic workup and accurate tissue diagnosis in differentiating primary amyloidosis and secondary amyloid deposition will be highlighted.
authors: Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD 21287, USA.
authors: Myriam
authors: M
authors: Loyo
authors: Alex
authors: A
authors: Baras
authors: Lee M
authors: LM
authors: Akst
mesh_terms: D000369:Aged, 80 and over; D000686:Amyloidosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007818:Laryngeal Diseases / Q000209:etiology*; D007822:Laryngeal Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D010954:Plasmacytoma / Q000150:complications* / Q000473:pathology / Q000601:surgery