title: Adverse effects of combined mycotoxins.
abstract: This article brings an overview of mycotoxin co-occurrence in foods in Croatia and neighbouring countries and experimental data from mycotoxin interaction studies involving Fusarium toxins, ochratoxin A (OTA), and aflatoxin B(1) (AFB(1)). Only a few studies of combined mycotoxin toxicity have employed a mathematical/ statistical design, while others have used common statistics in order to compare the effects of mycotoxin mixtures with effects of single toxins. So far, most studies have observed additive or synergistic effects, suggesting that these mixtures pose a significant threat to human and animal health.
authors: Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia.
authors: Maja
authors: M
authors: Šegvić Klarić
mesh_terms: D016604:Aflatoxin B1 / Q000633:toxicity; D000821:Animal Feed / Q000032:analysis; D000818:Animals; D045424:Complex Mixtures / Q000633:toxicity*; D017523:Croatia; D005506:Food Contamination / Q000032:analysis*; D037341:Fumonisins / Q000633:toxicity; D006801:Humans; D009183:Mycotoxins / Q000032:analysis* / Q000633:toxicity*; D009793:Ochratoxins / Q000633:toxicity
chemical_list: D045424:Complex Mixtures; D037341:Fumonisins; D009183:Mycotoxins; D009793:Ochratoxins; C025589:ochratoxin A; D016604:Aflatoxin B1