title: Plasticity of cerebral functions.
abstract: Over the past two decades, results from neurophysiological studies in animal models and neuroimaging studies in human populations have converged along a common thread. Neuroplasticity in the remaining, intact tissue accompanies functional recovery after brain injury. Now, virtually every new therapeutic approach in postinjury rehabilitation relies on the fundamental principles of neuroplasticity for theoretical validity. In this chapter, the basic tenets of plasticity are outlined, and the neural substrates in the cerebral cortex that may subserve recovered functions are reviewed.
authors: Department of Molecular and Integrative Physiology, KU Medical Center, Kansas City, KS, USA. rnudo@kumc.edu
authors: Randolph J
authors: RJ
authors: Nudo
authors: David
authors: D
authors: McNeal
mesh_terms: D000818:Animals; D001927:Brain Diseases / Q000473:pathology / Q000503:physiopathology; D002540:Cerebral Cortex / Q000166:cytology / Q000502:physiology*; D006801:Humans; D009473:Neuronal Plasticity / Q000502:physiology*; D020127:Recovery of Function