title: Cutaneous and mucosal phaeohyphomycosis caused by Exophiala spinifera in a pregnant patient: case report and literature review.
abstract: We report a case of mucocutaneous phaeohyphomycosis caused by Exophiala spinifera. Crusty plaques and nodules were major clinical features. Histological examination revealed brown yeast-like cells and hyphae. Mycological and molecular data identified E. spinifera as etiologic agent. Oral itraconazole was effective, which was in accordance with the results of in vitro susceptibility testing. We speculated that her pregnancy may play a role of risk factor in the infection by E. spinifera.
authors: Department of Mycology, Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing, People's Republic of China.
authors: Le
authors: L
authors: Wang
authors: Xiaodong
authors: X
authors: She
authors: Guixia
authors: G
authors: Lv
authors: Yongnian
authors: Y
authors: Shen
authors: Qing
authors: Q
authors: Cai
authors: Rong
authors: R
authors: Zeng
authors: Caixia
authors: C
authors: Li
authors: Yiping
authors: Y
authors: Ge
authors: Shuwen
authors: S
authors: Deng
authors: G S
authors: GS
authors: de Hoog
authors: Min
authors: M
authors: Li
authors: Weida
authors: W
authors: Liu
mesh_terms: D000284:Administration, Oral; D000935:Antifungal Agents / Q000008:administration & dosage; D005093:Exophiala / Q000302:isolation & purification*; D005260:Female; D006257:Head / Q000000981:diagnostic imaging; D006651:Histocytochemistry; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage; D008853:Microscopy; D009296:Nasal Cavity / Q000000981:diagnostic imaging; D009297:Nasal Mucosa / Q000382:microbiology / Q000473:pathology*; D060446:Phaeohyphomycosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology*; D011859:Radiography; D012867:Skin / Q000382:microbiology / Q000473:pathology*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole