title: Reversible zinc-induced injuries to erythrocyte membrane nanostructure.
abstract: Zinc-induced injuries to red blood cell membrane nanostructures at different zinc concentrations were studied by atomic force microscopy. In order to distinguish the intrinsic characteristics of membrane nanostructures, the membrane surfaces were represented by three orders using 3D Fourier transform. Increasing the concentrations of zinc ions modified the pattern of induced injuries: their depths and diameters and their number on the membrane surface test area increased. The injuries and their distribution for each order of membrane surface were analyzed. Albumin restored membrane nanosurface.
authors: V. A. Negovsky Institute of Intensive Care, Russian Academy of Medical Sciences, Moscow, Russia. am-chernysh@mail.ru
authors: A M
authors: AM
authors: Chernysh
authors: E K
authors: EK
authors: Kozlova
authors: V V
authors: VV
authors: Moroz
authors: V A
authors: VA
authors: Sergunova
authors: O Ye
authors: OY
authors: Gudkova
authors: M S
authors: MS
authors: Fedorova
mesh_terms: D000328:Adult; D004910:Erythrocyte Membrane / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D004912:Erythrocytes / Q000166:cytology / Q000187:drug effects* / Q000648:ultrastructure; D006801:Humans; D008297:Male; D018625:Microscopy, Atomic Force; D049329:Nanostructures; D015032:Zinc / Q000633:toxicity*
chemical_list: D015032:Zinc