title: The prognostic significance of SYNTAX score after early percutaneous transluminal coronary angioplasty for acute ST elevation myocardial infarction.
abstract: BACKGROUND
  SYNergy between percutaneous coronary intervention (PCI) with TAXUS and Cardiac Surgery (SYNTAX) score, which is based on the characteristics of atherosclerotic lesions and the complexity of coronary artery anatomy, is useful for choosing an intervention strategy, but its prognostic significance for acute ST elevation of myocardial infarction (STEMI) remains unknown. This study aimed to redress this issue.
  
  
  METHODS
  Our observational study included 151 consecutive patients admitted for acute STEMI who underwent primary PCI between January 1, 2008 and December 31, 2009. The primary endpoint for analysis was 30-day cardiac death.
  
  
  RESULTS
  Among the 151 patients, cardiac death occurred in 10 (7%) within 30 days. After the first month, five patients died of non-cardiac causes, but no cardiac death occurred. Multivariate analysis showed that SYNTAX score (odds ratio [OR], 13.79, 95% confidence interval [CI], 1.24-153.38; p=0.033) and a symptom onset-to-therapy time interval >4 h (OR, 11.13; 95% CI, 1.08-114.42; p=0.043) were independent risk factors for 30-day mortality. The SYNTAX score cut-off for discriminating low and high risk was 22.
  
  
  CONCLUSIONS
  SYNTAX score is an independent predictor of short-term cardiac mortality in patients with acute STEMI.
authors: Department of Second Section of Cardiology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Linkou, Taiwan.
authors: Chia-Hung
authors: CH
authors: Yang
authors: Ming-Jer
authors: MJ
authors: Hsieh
authors: Chun-Chi
authors: CC
authors: Chen
authors: Chao-Yung
authors: CY
authors: Wang
authors: Shang-Hung
authors: SH
authors: Chang
authors: Cheng-Hung
authors: CH
authors: Lee
authors: I-Chang
authors: IC
authors: Hsieh
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty; D003643:Death; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000401:mortality* / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D013997:Time Factors