title: [Vaccinations in patients with immunodeficiency or immunosuppressive therapy].
abstract: Patients with immunodeficiency and patients under immunosuppressive therapy have an increased risk of infectious diseases. Vaccination strategies are needed to protect them from preventable diseases. The underlying disease and severity of the immune impairment may have influence on indications and contra-indications of vaccines. Inactivated vaccines can be administered safely according to the current recommendations of the Permanent Commission on Vaccinations of the Robert-Koch-Institut in Berlin, Germany (STIKO). Depending on the severity of the immune dysfunction, antibody response to vaccinations varies. Where possible, the antibody response following vaccinations should be tested. Previously, attenuated live vaccines were considered to be strictly contra-indicated in immunocompromised patients. Today, the administration of attenuated live vaccines is thought to be possible, depending on the degree and type of immunodeficiency or immunosuppression of the individual.
authors: Zentrum für Innere Medizin, Klinik und Poliklinik für Innere Medizin II, Abteilung für Tropenmedizin,  Infektionskrankheiten und Sektion Nephrologie, Universitätsmedizin Rostock.
authors: D
authors: D
authors: Boršo
authors: M
authors: M
authors: Löbermann
authors: C
authors: C
authors: Fritzsche
authors: C
authors: C
authors: Hemmer
authors: A
authors: A
authors: Führer
authors: U
authors: U
authors: Zettl
authors: E C
authors: EC
authors: Reisinger
mesh_terms: D000075202:Contraindications; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications* / Q000188:drug therapy*; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007239:Infections / Q000209:etiology*; D014611:Vaccination
chemical_list: D007166:Immunosuppressive Agents