title: A case of hypogonadotropic hypogonadism caused by opioid treatment for nonmalignant chronic pain.
abstract: We report a case of 42-year-old male patient with hypogonadotropic hypogonadism. He suffered from general fatigue and erectile dysfunction after the treatment with transdermal fentanyl for chronic pain by traffic injury. Endocrine examinations and hormone stimulating tests showed that he had hypogonadotropic hypogonadism. Brain magnetic resonance imaging (MRI) showed no abnormal findings, and he had no past history of accounting for acquired hypogonadotropic hypogonadism. Therefore, his hypogonadism was diagnosed to be caused by opioid treatment. Although opioid-induced endocrine dysfunctions are not widely recognized, this case suggests that we should consider the possibility of endocrine dysfunctions in patients with opioid treatment.
authors: Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan.
authors: Yukiko
authors: Y
authors: Tabuchi
authors: Tetsuyuki
authors: T
authors: Yasuda
authors: Hideaki
authors: H
authors: Kaneto
authors: Tetsuhiro
authors: T
authors: Kitamura
authors: Junji
authors: J
authors: Kozawa
authors: Michio
authors: M
authors: Otsuki
authors: Akihisa
authors: A
authors: Imagawa
authors: Aya
authors: A
authors: Nakae
authors: Youichi
authors: Y
authors: Matsuda
authors: Hironobu
authors: H
authors: Uematsu
authors: Takashi
authors: T
authors: Mashimo
authors: Masahiko
authors: M
authors: Shibata
authors: Iichiro
authors: I
authors: Shimomura