title: [Long-term remission after nonmyeloablative allogeneic bone marrow transplantation in a relapsed Hodgkin lymphoma patient with CNS involvement].
abstract: Intracranial involvement of relapsed Hodgkin lymphoma (HL) is quite rare and its prognosis is very poor. We report a patient with relapsed HL with central nervous system (CNS) involvement after autologous stem cell transplantation successfully treated with allogeneic bone marrow transplantation with reduced intensity conditioning regimen. A standard therapy for relapsed CNS HL has not yet established. To the best of our knowledge, this is the first case report describing allogeneic stem cell transplantation for relapsed CNS HL in an elderly patient. Our results in this case suggest that allogeneic stem cell transplantation could be a useful therapeutic option in relapsed CNS HL patients, if their CNS lesions are controlled before stem cell transplantation.
authors: Department of Hematology, Tokyo Women's Medical University, Tokyo, Japan.
authors: Hanae
authors: H
authors: Shimura
authors: Yoichi
authors: Y
authors: Imai
authors: Midori
authors: M
authors: Ishiyama
authors: Kentaro
authors: K
authors: Yoshinaga
authors: Masayuki
authors: M
authors: Shiseki
authors: Naoki
authors: N
authors: Mori
authors: Masanao
authors: M
authors: Teramura
authors: Toshiko
authors: T
authors: Motoji
mesh_terms: D016026:Bone Marrow Transplantation / Q000379:methods; D002490:Central Nervous System / Q000473:pathology*; D005260:Female; D006689:Hodgkin Disease / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D055502:Secondary Prevention; D013997:Time Factors; D014184:Transplantation, Homologous / Q000379:methods; D016896:Treatment Outcome