title: Effects of surface functional groups on the formation of nanoparticle-protein corona.
abstract: Herein, we examined the dependence of protein adsorption on the nanoparticle surface in the presence of functional groups. Our UV-visible spectrophotometry, transmission electron microscopy, infrared spectroscopy, and dynamic light scattering measurements evidently suggested that the functional groups play an important role in the formation of nanoparticle-protein corona. We found that uncoated and surfactant-free silver nanoparticles derived from a laser ablation process promoted a maximum protein (bovine serum albumin) coating due to increased changes in entropy. On the other hand, bovine serum albumin displayed a relatively lower affinity for electrostatically stabilized nanoparticles due to the constrained entropy changes.
authors: Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Greenville, North Carolina 27834, USA.
authors: R
authors: R
authors: Podila
authors: R
authors: R
authors: Chen
authors: P C
authors: PC
authors: Ke
authors: J M
authors: JM
authors: Brown
authors: A M
authors: AM
authors: Rao