title: Influence of various tubal surgeries to serum antimullerian hormone level and outcome of the subsequent IVF-ET treatment.
abstract: OBJECTIVE
  To compare the influence of various tubal surgeries to ovarian reserve via serum level of antimullerian hormone (AMH) and the subsequent in vitro fertilization and embryo transplantation (IVF-ET) outcome in patients with simple tubal infertility.
  
  
  METHODS
  A prospective cohort study was conducted on 134 IVF cycles undegone by 26 and 34 cases with bilateral and unilateral salpingectomy, respectively, 23 cases with bilateral oviducts interrupted in the proximal and 51 cases with bilateral oviducts obstruction without intervention as controls.
  
  
  RESULTS
  Serum AMH displayed its great superiority to traditional markers of ovarian reserve in correspondence with antral follicles count and decisive effect for the number of oocytes retrieved after stimulation in each group. No significant differences on ovarian reserve and responsiveness or IVF-ET outcome existed among four groups comparable on essential characteristics, except for numerically higher clinical pregnancy rate and live birth rate after various tubal surgeries versus no intervention for bilateral oviducts obstruction. Especially, bilateral salpingectomy precursed the statistically highest implantation rate (51.0% versus 28.0%, 39.1%, 30.4%) and numerically best IVF outcome.
  
  
  CONCLUSIONS
  Tubal surgical procedures have some beneficial effect for improving IVF outcome without significant impact on ovarian reserve or responsiveness. Bilateral salpingectomy appears to be an appropriate procedure before IVF treatment for bilateral salpingitis, especially hydrosalpinx.
authors: Center of Clinical Reproduction, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
authors: Lili
authors: L
authors: Ni
authors: Saima
authors: S
authors: Sadiq
authors: Yundong
authors: Y
authors: Mao
authors: Yugui
authors: Y
authors: Cui
authors: Wei
authors: W
authors: Wang
authors: Jiayin
authors: J
authors: Liu
mesh_terms: D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood*; D010064:Embryo Implantation; D005184:Fallopian Tube Diseases / Q000097:blood / Q000601:surgery*; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000601:surgery / Q000628:therapy*; D010053:Ovary / Q000601:surgery; D010062:Ovulation Induction; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies; D058994:Salpingectomy; D016896:Treatment Outcome
chemical_list: D054304:Anti-Mullerian Hormone