title: Crying and spilling--time to stop the overmedicalisation of normal infant behaviour.
abstract: Many infants have periods of unsettledness, or irritability, over the first months of life. Spilling (or posseting) due to reflux of gastric contents is also seen very frequently. Almost universally, these are normal patterns of infancy (the first 12 months of life) that resolve with the passage of time. In recent years, these normal developmental processes have increasingly been ascribed to pathology and treated with medical therapies, including acid suppressants. There is clear evidence, however, that acid suppression has no role in the management of these behaviours. In addition, recent data illustrate increased risk of adverse effects of these drugs in infants.
authors: Department of Public Health and General Practice, University of Otago, Christchurch, New Zealand.
authors: Ben
authors: B
authors: Hudson
authors: Anna
authors: A
authors: Alderton
authors: Claire
authors: C
authors: Doocey
authors: Denise
authors: D
authors: Nicholson
authors: Les
authors: L
authors: Toop
authors: Andrew S
authors: AS
authors: Day
mesh_terms: D000897:Anti-Ulcer Agents / Q000008:administration & dosage* / Q000009:adverse effects; D002657:Child Development / Q000502:physiology*; D003448:Crying; D005764:Gastroesophageal Reflux / Q000503:physiopathology* / Q000517:prevention & control*; D006801:Humans; D007223:Infant; D018730:Infant Behavior / Q000502:physiology*; D007231:Infant, Newborn; D009853:Omeprazole / Q000008:administration & dosage* / Q000009:adverse effects; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data; D054328:Proton Pump Inhibitors / Q000008:administration & dosage* / Q000009:adverse effects; D014839:Vomiting / Q000503:physiopathology* / Q000517:prevention & control*
chemical_list: D000897:Anti-Ulcer Agents; D054328:Proton Pump Inhibitors; D009853:Omeprazole