The MONitoring Dialysis Outcomes (MONDO) initiative.
BACKGROUND
Systematic collection and analysis of global hemodialysis patient data may help to improve patient outcomes.


METHODS
The MONitoring Dialysis Outcomes (MONDO) initiative comprises data from eight dialysis providers worldwide. Data are combined into one repository. Extensive procedures are employed to merge data across countries and providers.


RESULTS
The MONDO database comprises longitudinal data of currently 128,000 hemodialysis patients from 26 countries on five continents. Here we report data from 62,345 incident hemodialysis patients. We found lower catheter rates in South-East Asia and Australia, lower hemoglobin levels in South-East Asia, and a higher prevalence of diabetes in North America. Longitudinal analyses suggest that there is a decline in interdialytic weight gain and serum phosphorus and an increasing neutrophil-to-lymphocyte ratio before death in all regions studied.


CONCLUSIONS
While organizationally lean and low-cost, MONDO is the largest global dialysis database initiative to date, with a particular focus on high longitudinal data density and geographical diversity.
Renal Research Institute, New York, NY 10128, USA. lusvyat@rriny.com
Len A
LA
Usvyat
Yosef S
YS
Haviv
Michael
M
Etter
Jeroen
J
Kooman
Daniele
D
Marcelli
Cristina
C
Marelli
Albert
A
Power
Ted
T
Toffelmire
Yuedong
Y
Wang
Peter
P
Kotanko
D000368:Aged; D001835:Body Weight; D016208:Databases, Factual; D057286:Electronic Health Records / Q000458:organization & administration*; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007391:International Cooperation; D007676:Kidney Failure, Chronic / Q000097:blood / Q000401:mortality / Q000628:therapy*; D007958:Leukocyte Count; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000706:statistics & numerical data*; D009504:Neutrophils / Q000473:pathology; D010758:Phosphorus / Q000097:blood; D006435:Renal Dialysis / Q000706:statistics & numerical data*; D016019:Survival Analysis; D016896:Treatment Outcome
D006454:Hemoglobins; D010758:Phosphorus