Activating germline R776H mutation in the epidermal growth factor receptor associated with lung cancer with squamous differentiation.
Academic Medical Center, Amsterdam, The Netherlands. c.j.vannoesel@amc.uva.nl
Jan
J
van Noesel
Ward H
WH
van der Ven
Theo A M
TA
van Os
Peter W A
PW
Kunst
Jitske
J
Weegenaar
Roy J A
RJ
Reinten
Rama K
RK
Kancha
Justus
J
Duyster
Carel J M
CJ
van Noesel
D000328:Adult; D001483:Base Sequence; D002289:Carcinoma, Non-Small-Cell Lung / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D004252:DNA Mutational Analysis; D004789:Enzyme Activation / Q000235:genetics; D066246:ErbB Receptors / Q000037:antagonists & inhibitors / Q000235:genetics* / Q000378:metabolism; D000069347:Erlotinib Hydrochloride; D005192:Family Health; D017809:Fatal Outcome; D005260:Female; D018095:Germ-Line Mutation; D006801:Humans; D017403:In Situ Hybridization; D008168:Lung / Q000187:drug effects / Q000473:pathology / Q000601:surgery; D008175:Lung Neoplasms / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged; D020125:Mutation, Missense; D018307:Neoplasms, Squamous Cell / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D011013:Pneumonectomy / Q000379:methods; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use; D011799:Quinazolines / Q000627:therapeutic use; D016896:Treatment Outcome
D047428:Protein Kinase Inhibitors; D011799:Quinazolines; D000069347:Erlotinib Hydrochloride; D066246:ErbB Receptors