[Study of the interaction between antigen-antibody complexes for label-free sensor application].
Nanomechanical cantilever systems have a great potential in design of the new type of label-free imunnosensors. They are based on the conversion of free energy change of the surface layer of the receptor by the reaction of molecular recognition between the antigen and antibody into mechanical deformation of microcantilever. But the mechanisms of molecular interactions in the layer are still not clear.
D V
DV
Kolesov
G A
GA
Kiselev
A A
AA
Kudrinskiĭ
I V
IV
Iaminskiĭ
D000818:Animals; D055910:Antibodies, Immobilized / Q000737:chemistry / Q000276:immunology; D000936:Antigen-Antibody Complex / Q000032:analysis* / Q000276:immunology; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods*; D004867:Equipment Design; D051379:Mice; D014508:Urea / Q000737:chemistry
D055910:Antibodies, Immobilized; D000936:Antigen-Antibody Complex; D014508:Urea