Metastatic medullary carcinoma of thyroid presenting as a dural-based mass: case report and review of literature.
Dural metastasis from medullary thyroid carcinoma (MTC) is not well established in English literature. We present the case report of MTC with unusual clinical presentation as a dural-based mass in a 39-year-old male with no family history of multiple endocrine neoplasia syndrome. Magnetic resonance imaging showed an extra-axial dural-based mass in right frontal lobe with calvarium and soft tissue extension to the right superior orbit. Histopathology showed MTC with variegated morphology and various patterns. Thyroid mass and widespread metastases from medullary thyroid carcinoma were subsequently identified.
Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, Hofstra North Shore-LIJ School of Medicine, 6 Ohio Drive, Suite 202, Lake Success, NY 11042, USA.
Arvind
A
Rishi
Steven
S
Savona
Karen
K
Black
Michael
M
Schulder
Jian Yi
JY
Li
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000097:blood; D001932:Brain Neoplasms / Q000473:pathology* / Q000556:secondary*; D018276:Carcinoma, Medullary / Q000473:pathology* / Q000556:secondary*; D004388:Dura Mater / Q000473:pathology*; D005094:Exophthalmos / Q000209:etiology; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology* / Q000556:secondary*; D013964:Thyroid Neoplasms / Q000473:pathology*
D014408:Biomarkers, Tumor