[Safty action of heat shock protein 27 in reperfusion after spinal marrow ischemia].
Heat shock protein 27 belongs to the heat shock protein family in the small molecular weight family. This review collected a number of literature to analyze the expression meaning and mechanism of HSP27,expounded HSP27 with inhibition of NO production, maintenance of cell protein stability and accelerated cell damage repair function. At the same time, HSP27 also has a resistance to apoptosis, protecting mitochondria, inhibiting activation of nuclear factor and other related functions. The heat shock protein 27 has protection in spinal cord ischemia-reperfusion.
Department of Orthopaedics, the First Affiliated Hospital of Fuzhou General Hospital of Nanjing Military, Putian 351100, Fujian, China. xjp2001-123@163.com
Jian-Ping
JP
Xu
Wen-Rong
WR
Guo
Guo-Bing
GB
Lin
D017209:Apoptosis; D055551:HSP27 Heat-Shock Proteins / Q000502:physiology*; D006801:Humans; D009569:Nitric Oxide / Q000096:biosynthesis; D015427:Reperfusion Injury / Q000517:prevention & control*; D013116:Spinal Cord / Q000098:blood supply*
D055551:HSP27 Heat-Shock Proteins; D009569:Nitric Oxide