Primary bone xanthoma of the inferior orbital rim.
Primary bone xanthoma is an extremely rare benign bone tumor histologically characterized by mononuclear macrophage-like cells, abundant foam cells, and multinucleated giant cells. Xanthomas of the bone usually appear as a benign secondary manifestation of some diseases. Therefore, they are denominated primary xanthomas when the other diseases are discarded.We report a peculiar case of primary bone xanthoma of the inferior orbital rim in the absence of hyperlipidemic conditions. Surgical intervention was performed under local anesthesia via a subtarsal 1-cm incision. Histopathological examination confirmed the diagnosis of bone xanthoma. Primary bone xanthomas are extremely rare. Diagnosis of such lesions is challenging and requires both radiographic and histopathological features assessment. A careful work-up and a full lipid profile should be performed to rule out underlying diseases.
Division of Maxillofacial Surgery, Head and Neck Department, San Giovanni Battista Hospital, University of Turin, Turin, Italy. paolo.boffano@gmail.com
Paolo
P
Boffano
Cesare
C
Gallesio
Paola
P
Campisi
Rodolfo
R
Benech
Fabio
F
Roccia
Sid
S
Berrone
D000328:Adult; D001706:Biopsy; D006801:Humans; D008297:Male; D009915:Orbit / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014973:Xanthomatosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*