Agreement between skin testing and QuantiFERON-TB Gold In-Tube assay (QFT-TB) in detecting latent tuberculosis infection among household contacts in India.
OBJECTIVE
The present study was designed to find the agreement between Tuberculin Skin Test and interferon gamma assay test in detecting latent tuberculosis infection in household contacts of sputum culture positive tuberculosis cases.


METHODS
Department of Community Medicine, Christian Medical College, Vellore.


METHODS
One hundred and fifty household contacts of sputum culture positive tuberculosis cases were tested with both the methods simultaneously and actual as well as kappa agreement was determined.


RESULTS
The overall actual agreement between both the tests was found to be 82% with a kappa agreement of 0.57.


CONCLUSIONS
The agreement was very high (both percentage agreement and Kappa) in pediatric contacts but it was poor in adult contacts.
Department of Community Medicine, Kalinga Institute of Medical Sciences (KIMS), KIIT University, Bhubaneswar, Odisha. drsatyajitpattnaik@gmail.com
Satyajit
S
Pattnaik
K R
KR
John
E
E
Shalini
J S
JS
Michael
D000328:Adult; D002648:Child; D003430:Cross-Sectional Studies; D005191:Family Characteristics; D006801:Humans; D007194:India / Q000453:epidemiology; D055985:Latent Tuberculosis / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D011933:Reagent Kits, Diagnostic; D013183:Sputum / Q000382:microbiology; D014374:Tuberculin Test / Q000379:methods*
D011933:Reagent Kits, Diagnostic