18F-FDG imaging of the primary breast leiomyosarcoma and follow-up lung metastasis.
A 46-year-old woman presented with a large left breast mass. FDG PET/CT demonstrated a large left breast mass (SUV = 28). Preoperative biopsy showed malignant sarcoma. Modified radical mastectomy was performed. Immunohistochemical analysis using h-caldesmon and smooth muscle actin staining established the diagnosis of primary breast leiomyosarcoma. Despite intensive chemotherapy, 3-month follow-up PET/CT revealed a large lung metastasis suggesting aggressiveness and poor response to chemotherapy. Primary leiomyosarcoma of the breast is extremely rare and difficult to diagnose before excisional surgery because of the need for immunohistochemical staining to confirm the diagnosis.
Department of Nuclear Medicine, Myongji Hospital, Kwandong University College of Medicine, Goyang, Republic of Korea.
Moonsun
M
Pai
Seok-Nam
SN
Yoon
D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D019788:Fluorodeoxyglucose F18; D005500:Follow-Up Studies; D006801:Humans; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging* / Q000473:pathology*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed
D019788:Fluorodeoxyglucose F18