Criticial limb ischemia: epidemiology.
Critical limb ischemia is found in 12% of the U.S. adult population. Its clinical presentation varies from no symptoms to intermittent claudication, atypical leg pain, rest pain, ischemic ulcers, or gangrene. Those with critical limb ischemia have a high incidence of cardiovascular comorbidities that reflect a significant systemic atherosclerotic burden; they have increased functional impairment and increased rates of functional decline compared with persons without critical limb ischemia. Interventions for critical limb ischemia and the impact of major amputation have a significant social and economic impact. At 1 year, 25% of patients will be dead, 30% will have undergone amputation, and only 45% will remain alive with both limbs. At 5 years, more than 60% of patients with critical limb ischemia will be dead.
Methodist DeBakey Heart & Vascular Center, The Methodist Hospital, Houston, Texas, USA.
Mark G
MG
Davies
D014943:Global Health; D006801:Humans; D007511:Ischemia / Q000453:epidemiology*; D007866:Leg / Q000098:blood supply*; D009017:Morbidity / Q000639:trends; D015996:Survival Rate / Q000639:trends
amputation; cardiovascular disease; cardiovascular risk factors; claudication; critical limb ischemia; peripheral arterial disease