[Idiopathic pulmonary fibrosis and sleep disorders].
Idiopathic pulmonary fibrosis (IPF) is the most common interstitial lung disease. Despite progress made in understanding the pathophysiological mechanisms behind the development of the disease, its prognosis is poor. For this reason, any measure to improve the quality of life for these patients should be preferred. Some authors are interested in sleep disorders, and possible impact on quality of life. Patients with IPF have lowered scores of quality of life compared to those found in general population, with some correlation with the scores of sleep quality. There is a hyperfragmentation with many arousals and desaturation events. Some authors also report an apnea-hypopnea index higher in these patients, but these data are not found in all the studies. Correcting these obstructive phenomena may have a beneficial effect on survival, which would make systematic the sleep assessment in these patients. Finally, the relationship between IPF, gastroesophageal reflux and sleep apnea syndrome remains unclear.
Service de pneumologie et immunoallergologie, centre de compétence maladies pulmonaires rares, clinique des maladies respiratoires, université de Lille 2, hôpital Calmette, CHRU de Lille, boulevard Leclercq, 59037 Lille, France.
N
N
Gusbin
S
S
Fry
A
A
Mallart
B
B
Wallaert
D005764:Gastroesophageal Reflux / Q000503:physiopathology*; D006801:Humans; D054990:Idiopathic Pulmonary Fibrosis / Q000150:complications / Q000503:physiopathology*; D011379:Prognosis; D011788:Quality of Life; D012891:Sleep Apnea Syndromes / Q000503:physiopathology; D012893:Sleep Wake Disorders / Q000150:complications / Q000503:physiopathology*