Endovascular embolization of ruptured and unruptured posterior circulation aneurysms. A multi-factor analysis.
OBJECTIVE
Complete aneurysm obliteration reduces the risk of rebleeding and is an     important goal of the aneurysm treatment.


METHODS
A retrospective     analysis of 63 patients undergoing endovascular treatment of posterior     circulation aneurysms. The occlusion rate was stratified to three groups:     complete, incomplete and partial. In the analysis compared the influence of the     selected characteristics: age, sex, WFNS grade, aneurysm location, size of the     aneurysm dome and neck, neck to dome ratio, on the effectiveness of embolization     in each group. A multi-factor analysis with probit model and linear regression     was applied to assess the impact of all characteristics on the complete     occlusion.


RESULTS
In the series of 63 single aneurysms, 51 were ruptured and     12 unruptured aneurysms. Complete occlusion was achieved in 36 (57.1%),     incomplete in 15 (23.8%), partial in 12 (19%) patients. In patients with the     neck size of 1-2 mm the complete occlusion was in 75% (24/32) incomplete in     12,5% (4/32), while when the neck size was 2-4 mm these rates were 38.7% (12/31)     and 29% (9/31) respectively. The predictor of total occlusion in probit and     linear regression model was only one independent variable, the narrow-neck size.


CONCLUSIONS
Multi-factor analysis found that the strongest predictor of the     complete occlusion is the aneurysm neck size.
Institute Psychiatry and Neurology, Department of Neurosurgery, Warsaw, Poland. ttomasz@mp.pl
Tomasz
T
Tykocki
Paweł
P
Nauman
Bogusław
B
Kostkiewicz
D000328:Adult; D000368:Aged; D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy*; D002533:Cerebral Angiography; D002560:Cerebrovascular Circulation; D004621:Embolization, Therapeutic / Q000379:methods*; D057510:Endovascular Procedures / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome; D055815:Young Adult