Do all candidemic patients need an ophthalmic examination?
Intraocular candidiasis is a potentially sight-threatening complication of candidemia. While the incidence of candidemia in North America has increased, the prevalence of intraocular candidiasis appears to be decreasing. In the USA and Europe, an ophthalmic examination is recommended for all candidemic patients to rule out intraocular involvement. However, improvements in management, clarification of the diagnosis, and trends in the epidemiology of intraocular candidiasis suggest that some candidemia patients might be safely managed without the recommended dilated ophthalmic examination.
Department of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA. mjv@med.unc.edu
Michael J
MJ
Vinikoor
Jonathan
J
Zoghby
Kenneth L
KL
Cohen
Joseph D
JD
Tucker
D002175:Candida / Q000302:isolation & purification; D058387:Candidemia / Q000150:complications* / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D003941:Diagnostic Techniques, Ophthalmological / Q000191:economics / Q000706:statistics & numerical data*; D015821:Eye Infections, Fungal / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D015994:Incidence; D009887:Ophthalmoscopy / Q000191:economics / Q000706:statistics & numerical data*; D015995:Prevalence; D012307:Risk Factors; D014481:United States