Gold nanotip array for ultrasensitive electrochemical sensing and spectroscopic monitoring.
A gold nanotip array platform with a combination of ultrasensitive electrochemical sensing and spectroscopic monitoring capability is reported. Adenosine triphosphate is detected down to 1 pM according to the impedance changes in response to aptamer-specific binding. Furthermore, the local molecular information can be monitored at the individual plasmonic nanotips, and hence provide the capability for a better understanding of complex biological processes.
School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, 639798, Singapore.
Yueyue
Y
Jiang
Fanben
F
Meng
Dianpeng
D
Qi
Pingqiang
P
Cai
Zongyou
Z
Yin
Fangwei
F
Shao
Hua
H
Zhang
Freddy
F
Boey
Xiaodong
X
Chen
D000255:Adenosine Triphosphate / Q000032:analysis; D004247:DNA / Q000737:chemistry; D004129:Dimethylpolysiloxanes / Q000737:chemistry; D055664:Electrochemical Techniques / Q000295:instrumentation*; D006046:Gold / Q000737:chemistry*; D008751:Methylene Blue / Q000737:chemistry; D036103:Nanotechnology / Q000295:instrumentation*; D013059:Spectrum Analysis, Raman
D004129:Dimethylpolysiloxanes; D006046:Gold; D000255:Adenosine Triphosphate; D004247:DNA; D008751:Methylene Blue
adenosine triphosphate; nanotip arrays; raman scattering; redox electrochemistry