Meta-analysis of effects of microbial phytase on digestibility and bioavailability of copper and zinc in growing pigs.
A meta-analysis was conducted to determine the effect of microbial phytase in pig diets on digestibility and bioavailability of Cu and Zn. Studies (n = 22) into effects of microbial phytase on digestibility and plasma levels of Cu and Zn were included in a dataset and regression analysis was performed to quantify the effect of Aspergillus niger derived 3-phytase in studies (n = 14) with a maximum dietary Zn content of 100 mg/kg and a maximum Cu addition of 20 mg/kg. Phytase inclusion increased digestibility of Zn (P = 0.003) and plasma Zn content (P < 0.001) without affecting digestibility and plasma level of Cu. Based on a comparison with dose-response studies with Zn, we estimated 500 phytase units (FTU) of microbial phytase is equivalent to 27 mg of Zn from ZnSO(4).
Wageningen UR Livestock Research, Lelystad, The Netherlands. paul.bikker@wur.nl
P
P
Bikker
A W
AW
Jongbloed
J T N M
JT
Thissen
D010832:6-Phytase / Q000378:metabolism / Q000494:pharmacology*; D000818:Animals; D001682:Biological Availability; D003300:Copper / Q000097:blood / Q000493:pharmacokinetics*; D013552:Swine / Q000254:growth & development / Q000502:physiology*; D015032:Zinc / Q000097:blood / Q000493:pharmacokinetics*
D003300:Copper; D010832:6-Phytase; D015032:Zinc