Deafness and blindness in a renal transplant recipient with cryptococcal meningitis.
Infections are a major determinant of outcome in kidney transplantation. Opportunistic pathogens are common in kidney recipients and several organs can be affected. Central nervous system infection in transplant recipients is a medical emergency. There is limited information in the literature concerning post-transplantation cryptococcal infection. Deafness and blindness are not classic findings. We report a case of meningocerebral cryptococcosis complicated by deafness and blindness after kidney transplantation. Physicians need to consider the possibility of Cryptococcus neoformans when symptoms persist despite empiric antimicrobial therapy.
Department of Nephrology, EPS Fattouma Bourguiba, Monastir, Tunisia. alouisabra@yahoo.fr
Sabra
S
Aloui
Mohamed
M
Gorcii
Habib
H
Skhiri
Lamia
L
Jaafoura
Imene
I
Gorsane
Nasr Ben
NB
Dhia
Ameur
A
Frih
Rached
R
Azaeiz
Elmezri
E
Elmayl
D000328:Adult; D001299:Audiometry; D001707:Biopsy, Needle; D001766:Blindness / Q000175:diagnosis / Q000209:etiology*; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D003638:Deafness / Q000175:diagnosis / Q000209:etiology*; D017809:Fatal Outcome; D005260:Female; D006084:Graft Rejection / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007668:Kidney / Q000382:microbiology / Q000473:pathology; D016030:Kidney Transplantation / Q000009:adverse effects*; D016919:Meningitis, Cryptococcal / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D007690:Polycystic Kidney Diseases / Q000628:therapy; D014057:Tomography, X-Ray Computed