Autoclaved autologous bone graft for orbital reconstruction for recurrent temporal bone orbital osteosarcoma.
Post-tumor excision and reconstruction of the craniofacial region is a complex and technically demanding process due to its proximity to numerous vital structures and irregularly shaped bony tissue. As such, novel methods are needed when reconstruction of irregularly shaped structures is necessary. Autoclaving of autologous bone grafts is an established practice in orthopedic and neurosurgical practice, but has only been described twice previously for orbital reconstruction. We performed grafting of an autoclaved autologous bone segment as part of surgery on a 30-year-old man to treat his recurrent temporal osteosarcoma with orbital involvement, which is rare. In addition, we went on to highlight key differences between bone autoclaving and pasteurization, an alternative heat treatment technique, for orbital reconstruction post-tumor excision. Although he suffered a second recurrence 8 months later, there was no evidence of recurrence in the autoclaved bone. To treat his second recurrence, he subsequently underwent a modified eyelid-conjunctiva sparing orbital exenteration, also an uncommonly performed procedure. Also, we subsequently examined the novel technique of a lid-sparing and conjunctiva-sparing orbital exenteration and its benefits. He continues to remain under follow-up.
Department of Ophthalmology, National University Cancer Institute, Singapore, Singapore.
Jinesh M
JM
Shah
Alvin
A
Wong
Thiam Chye
TC
Lim
Jane
J
Lim
Lee Khai
LK
Mun
Chou
C
Ning
Bengt Fredrik
BF
Petersson
Gangadhara
G
Sundar
D000328:Adult; D016025:Bone Transplantation / Q000379:methods*; D003131:Combined Modality Therapy; D003399:Craniotomy; D018450:Disease Progression; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009364:Neoplasm Recurrence, Local; D009918:Orbital Neoplasms / Q000473:pathology / Q000601:surgery*; D012516:Osteosarcoma / Q000473:pathology / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D013242:Sterilization; D014182:Transplantation, Autologous