Double parallel dynamic resolution through lipase-catalyzed asymmetric transformation.
Dynamic systems based on double parallel reactions have been generated and resolved in situ by secondary lipase-catalyzed asymmetric transformation, resulting in high chemo- and enantioselectivities.
Department of Chemistry, KTH - Royal Institute of Technology, Teknikringen 30, Stockholm, Sweden.
Yan
Y
Zhang
Lei
L
Hu
Olof
O
Ramström
D000080:Acetals / Q000737:chemistry / Q000378:metabolism*; D001547:Benzaldehydes / Q000737:chemistry / Q000378:metabolism; D055162:Biocatalysis; D006575:Heterocyclic Compounds, 3-Ring / Q000737:chemistry / Q000378:metabolism*; D008049:Lipase / Q000737:chemistry / Q000378:metabolism*; D015394:Molecular Structure; D009574:Nitro Compounds / Q000737:chemistry / Q000378:metabolism*; D013816:Thermodynamics
D000080:Acetals; D001547:Benzaldehydes; D006575:Heterocyclic Compounds, 3-Ring; D009574:Nitro Compounds; C560828:nitroaldol; D008049:Lipase