[Clinical study of bi yan qing du ke li and nasal care in treatment of patients with nasopharyngeal carcinoma after radiotherapy].
OBJECTIVE
To investigate the effect of bi yan qing du ke li combined with Nasal Care on the titers of EB virus VCA/IgA and nasopharyngeal symptoms in patients with nasopharyngeal carcinoma(NPC) after radiotherapy.


METHODS
Sixty NPC patients underwent-radiotherapy were randomly divided into study group (bi yan qing du ke li combined with nasal care, n=30) and control group (bi yan qing du ke li group, n=30).


RESULTS
After treatment, the geometric mean titer of VCA/IgA was 20.5 in study group and 55.6 in control group, respectively (P < 0.05). Meanwhile, the nasopharyngeal symptoms after treatment in study group was improved significantly better than that of control group (P < 0.05).


CONCLUSIONS
The application of bi yan qing du ke li combined with Nasal Care can significantly decrease the titers of VCA/IgA in NPC patients after-radiotherapy and improve the nasopharyngeal symptoms, which might be helpful to decrease the recurrence rate of NPC.
Department of Otorhinolaryngology, the First People's Hospital of Xianning, Xianning, 437000, China. 654776731@qq.com
Hua
H
Shi
D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000097:blood / Q000276:immunology; D000956:Antigens, Viral / Q000097:blood / Q000276:immunology; D036022:Capsid Proteins / Q000097:blood / Q000276:immunology; D002277:Carcinoma; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood / Q000276:immunology; D008297:Male; D008875:Middle Aged; D000077274:Nasopharyngeal Carcinoma; D009303:Nasopharyngeal Neoplasms / Q000276:immunology / Q000532:radiotherapy / Q000628:therapy*; D011379:Prognosis
D000914:Antibodies, Viral; D000956:Antigens, Viral; D036022:Capsid Proteins; D004365:Drugs, Chinese Herbal; C041788:Epstein-Barr viral capsid antigen; D007070:Immunoglobulin A