[Endocrinology in 2012: what's new?].
Maternal hypothyroidism has been associated with intellectual impairment in offspring and, subsequently, routine thyroid screening during pregnancy remains controversial. However current literature has reported no benefit of systematic thyroid screening and substitution with levothyroxine of hypothyroid pregnant women on cognitive function in offspring. Recent studies suggest that subclinical hypothyroidism and hyperthyroidism, especially those with TSH >10 mIU/l or <0.1 mIU/l are associated with cardiovascular morbidity and mortality. Genetic markers are being studied in order to clarify the nature of benign or malignant thyroid nodules after fine-needle aspiration whom cytology is indeterminate. They could avoid the need for surgery in many cases.
Service de médecine interne générale, HUG, 1211 Genève 14. david.parrat@hcuge.ch
D
D
Parrat
P
P
Meyer
D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D003409:Congenital Hypothyroidism / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D004704:Endocrinology / Q000379:methods / Q000639:trends*; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D008403:Mass Screening; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis; D011296:Prenatal Diagnosis; D012307:Risk Factors; D016606:Thyroid Nodule / Q000175:diagnosis