A case of hypersensitivity to mosquito bites without peripheral natural killer cell lymphocytosis in a 6-year-old Korean boy.
Hypersensitivity to mosquito bites (HMB) is a rare disease characterized by intense skin reactions such as bulla and necrotic ulcerations at bite sites, accompanied by general symptoms such as high-grade fever and malaise occurred after mosquito bites. It has been suggested that HMB is associated with chronic Epstein-Barr virus (EBV) infection and natural killer (NK) cell leukemia/lymphoma. We describe here a Korean child who presented with 3-yr history of HMB without natural killer cell lymphocytosis. He has been ill for 6 yr with HMB. Close observation and examination for the development of lymphoproliferative status or hematologic malignant disorders is needed.
Department of Pediatrics, Dongguk University Ilsan Hospital, Goyang, Korea.
Han-Su
HS
Seon
Ji-Hyeon
JH
Roh
Seung-Ho
SH
Lee
Eun-Kyeong
EK
Kang
D002648:Child; D020031:Epstein-Barr Virus Infections / Q000150:complications; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000209:etiology; D007299:Insect Bites and Stings / Q000175:diagnosis* / Q000473:pathology; D007694:Killer Cells, Natural / Q000276:immunology; D008218:Lymphocytosis / Q000150:complications / Q000473:pathology; D008297:Male; D056910:Republic of Korea; D012867:Skin / Q000473:pathology
Epstein-Barr Virus; Hypersensitivity; Mosquito Bites; Natural Killer Cell