Mutagenic and antimutagenic properties of some lichen species grown in the Eastern Anatolia Region of Turkey.
All the methanol extracts did not show mutagenic activity in Ames/Salmonella and Z. mays MI test systems. Furthermore, some extracts showed significant antimutagenic activity against 9-AA in Ames test system. Inhibition rates for 9-AA mutagenicity ranged from 25.51% (P. furfuracea - 0.05 microg/plate) to 66.14% (C. islandica - 0.05 microg/plate). In addition, all of the extracts showed significant antimutagenic activity against sodium azide (NaN3) mutagenicity on MI values of Z. mays.
Department of Biology, Kazim Karabekir Education Faculty, Atatürk University, Erzurum 25240, Turkey.
A
A
Aslan
M
M
Gulluce
G
G
Agar
M
M
Karadayi
S
S
Bozari
F
F
Orhan
D000585:Aminacrine / Q000494:pharmacology; D016587:Antimutagenic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D045424:Complex Mixtures / Q000302:isolation & purification / Q000494:pharmacology*; D008011:Lichens / Q000737:chemistry*; D000432:Methanol; D008938:Mitosis / Q000187:drug effects* / Q000235:genetics; D008940:Mitotic Index; D009152:Mutagenicity Tests; D009153:Mutagens / Q000494:pharmacology; D018517:Plant Roots / Q000187:drug effects / Q000235:genetics; D012486:Salmonella typhimurium / Q000187:drug effects / Q000254:growth & development; D019810:Sodium Azide / Q000494:pharmacology; D012997:Solvents; D014421:Turkey; D003313:Zea mays / Q000187:drug effects / Q000235:genetics
D016587:Antimutagenic Agents; D045424:Complex Mixtures; D009153:Mutagens; D012997:Solvents; D000585:Aminacrine; D019810:Sodium Azide; D000432:Methanol