Follicular dendritic cell sarcoma of the tonsil.
Follicular dendritic cell sarcoma (FDCS) is an uncommon tumour within the spectrum of histiocytic and dendritic cell neoplasms that can occur at nodal and extra-nodal sites. Besides being rare, these tumours are difficult to diagnose. A 72-year-old man with a painless mass in the right tonsil was admitted to the Mersin University Hospital. Tonsillectomy was performed. Microscopically, the tumour consisted of spindle-shaped cells with large oval to polygonal nuclei. Lymphocytes were scattered among the tumour cells. Immunohistochemically, the cells were positive for CD23 and vimentin. The tumour was diagnosed as FDCS with histological and immunohistochemical findings. Recognition of extranodal FDCS requires knowledge of this entity and to consider it during the diagnosis. Confirmatory immunohistochemical staining is essential for diagnosis. Correct characterisation of this neoplasm is important because of its potential for recurrence and metastasis.
Department of Pathology, Mersin University, School of Medicine, Mersin, Turkey.
Tuba
T
Kara
Ebru
E
Serinsoz
Rabia Bozdogan
RB
Arpaci
Yusuf
Y
Vayisoglu
D000368:Aged; D017024:Chemotherapy, Adjuvant; D054740:Dendritic Cell Sarcoma, Follicular / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D014067:Tonsillar Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D016312:Treatment Refusal