Oral manifestations of epidermolysis bullosa dystrophica: a rare genetic disease.
Epidermolysis bullosa (EB) constitutes a group of phenotypically diverse genodermatoses, which manifests with blistering and erosions of the skin and mucous membranes as the unifying diagnostic feature. It is an acquired disease or inherited as either autosomal-dominant or recessive with an incidence of 1/50 000. The prominent clinical characteristic of the disease is the development of bullae or vesicles in mucosa or skin in response to minor trauma. It is a chronic mechanobullous disease characterised by auto antibodies against Type VII collagen. This paper documents a case of a man diagnosed with dominant dystrophic EB; describing the measures that dentists and healthcare providers should adopt in order to provide a safe and effective dental treatment. Early prevention protocols for these patients have also been discussed.
Department of Oral and Maxillofacial Surgery,  Bharti Vidyapeeth Dental College & Hospital, Sangli, Maharashtra,  India.
Anita Dundappa
AD
Parushetti
Jiwanasha Manish
JM
Agrawal
Lalita Girish
LG
Nanjannawar
Manish Suresh
MS
Agrawal
D003937:Diagnosis, Differential; D016108:Epidermolysis Bullosa Dystrophica / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D008297:Male; D009059:Mouth Diseases / Q000175:diagnosis* / Q000235:genetics; D009061:Mouth Mucosa / Q000473:pathology*; D010641:Phenotype; D035583:Rare Diseases / Q000235:genetics*; D055815:Young Adult