Assessment of frequency of regression and progression of mild cervical neoplasia--LGSIL in women with positive high-risk HPV DNA test result.
OBJECTIVE
Assessment of frequency of regression and progression of mild cervical neoplasia in women positive for types of HPV DNA of high oncogenic potential.


METHODS
111 women were studied. One-year-long observation of patients included cervical cytology conducted every three months, and colposcopy conducted every six months. After a period of 12 months all women were evaluated with colposcopy and directed biopsies of abnormal cervical tissue.


RESULTS
This study confirms the significant effect of age on both regression and progression of low-grade cervical intraepithelial neoplasia.


CONCLUSIONS
In the age group below 26 years, complete regression of LGSIL occurs significantly more frequently than in older women. Whereas in the over 36 age group, progression to HGSIL occurred more frequently during 12 months of follow-up.
Department of Gynecologic Oncology, Karol Marcinkowski University of Medical Sciences, Poznań, Poland. dominik.pruski@oxytop.pl
Dominik
D
Pruski
Joanna
J
Fraszczak
Kinga
K
Iwaniec
Marcin
M
Przybylski
Witold
W
Kedzia
Anna
A
Gretkiewicz-Tomczyk
Agata
A
Karowicz-Bilińska
Marek
M
Spaczyński
D000328:Adult; D004279:DNA, Viral / Q000302:isolation & purification*; D018450:Disease Progression; D005260:Female; D061809:Human Papillomavirus DNA Tests / Q000706:statistics & numerical data*; D006801:Humans; D008403:Mass Screening / Q000706:statistics & numerical data; D027383:Papillomaviridae / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000821:virology*; D011247:Pregnancy; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000821:virology*; D055815:Young Adult; D002578:Uterine Cervical Dysplasia / Q000473:pathology / Q000821:virology*
D004279:DNA, Viral