Evaluation of the estrogenic effects of bisphenol-A on male freshwater prawn Macrobrachium asperulum.
Bisphenol-A(BPA), a known endocrine-disrupting chemical that is distributed world wide, is extensively employed in industry, dentistry and consumer household products. This study was conducted to explore the estrogenic effects of BA on the male freshwater prawn, Macrobrachium asperulum, by examining the daily survival rate, molting frequency, hepatosomatic index (HSI), and levels of vitellogenin-like protein. Results revealed that BPAcan elicitthe expression of vitellogenin-like protein (0.09 and 0.09 microg P x (mg protein))-1), respectively) in male organisms exposed to 0.1 and 1 ng l(-1) BPA at day 7. Moreover, prawns were perceived to be sensitive to estrogenic compounds. Hence, it can be concluded that M. asperulum can be used as a species for biomonitoring, and levels of vitellogenin-like protein in males are a useful biomarker for detecting estrogenic contaminations.
Institute of Fisheries Science, National Taiwan University, Taipei, Taiwan 106, R.O.C.
Kai-Hsiang
KH
Huang
Yuh-Wen
YW
Chiu
Shu-Yin
SY
Wang
Hon-Cheng
HC
Chen
Da-Ji
DJ
Huang
D000818:Animals; D001559:Benzhydryl Compounds / Q000008:administration & dosage / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D004958:Estradiol / Q000633:toxicity; D004968:Estrogens, Non-Steroidal / Q000008:administration & dosage / Q000633:toxicity*; D008297:Male; D033541:Palaemonidae / Q000187:drug effects*; D010636:Phenols / Q000008:administration & dosage / Q000633:toxicity*; D012741:Sexual Maturation / Q000187:drug effects; D014874:Water Pollutants, Chemical / Q000008:administration & dosage / Q000633:toxicity*; D000098826:Bisphenol A Compounds
D001559:Benzhydryl Compounds; D004958:Estradiol; D004968:Estrogens, Non-Steroidal; D010636:Phenols; D014874:Water Pollutants, Chemical; C006780:bisphenol A; D000098826:Bisphenol A Compounds