Statin-induced myopathy in a patient with previous poliomyelitis.
This report describes a patient with a history of poliomyelitis who developed new, progressive symptoms of muscle fatigue and weakness, suggestive of postpoliomyelitis syndrome. However, comprehensive investigations led to the diagnosis of statin-induced myopathy as the cause of the patient's symptoms. This case highlights the possibility of statin-induced myopathy in patients with a history of poliomyelitis and the differential diagnosis between postpoliomyelitis syndrome and statin-induced myopathy in these patients. The possibility of statin-induced myopathy should be considered when patients with previous poliomyelitis who take statin medication develop symptoms suggestive of postpoliomyelitis syndrome.
From the Department of Neurology (MHM, JL), Department of Pathology (MG), and Department of Radiology (IK), University of Turku and Turku University Hospital, Turku, Finland.
Mika H
MH
Martikainen
Maria
M
Gardberg
Ia
Ia
Kohonen
Janne
J
Lähdesmäki
D003327:Coronary Disease / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000139:chemically induced* / Q000175:diagnosis* / Q000628:therapy; D016262:Postpoliomyelitis Syndrome / Q000150:complications*; D017035:Pravastatin / Q000009:adverse effects*
D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D017035:Pravastatin