[Tissue factor in endothelial cells--its structure and function according to the current literature].
Tissue factor (TF) is a glycosylated transmembrane protein, expressed by endothelial and other cells. Its best known function is the initiation of thrombus formation, but TF also participates in inflammation processes. This article presents the established knowledge of TF expression in endothelial cells and current opinions on encrypted TF form and mechanisms of its activation.
Warszawski Uniwersytet Medyczny, Wydział Nauki o Zdrowiu, Zakład Biochemii Ogólnej i Zywności, Warszawa. jdrozdowska@wum.edu.pl
Joanna
J
Drozdowska
D000818:Animals; D042783:Endothelial Cells / Q000378:metabolism*; D004730:Endothelium, Vascular / Q000378:metabolism; D005786:Gene Expression Regulation; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D008958:Models, Molecular; D013925:Thromboplastin / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D013927:Thrombosis / Q000378:metabolism
D013925:Thromboplastin