Automatic detection of REM sleep in subjects without atonia.
Idiopathic Rapid-Rye-Movement (REM) sleep Behavior Disorder (iRBD) is a strong early marker of Parkinson's Disease and is characterized by REM sleep without atonia (RSWA) and increased phasic muscle activity. Current proposed methods for detecting RSWA assume the presence of a manually scored hypnogram. In this study a full automatic REM sleep detector, using the EOG and EEG channels, is proposed. Based on statistical features, combined with subject specific feature scaling and post-processing of the classifier output, it was possible to obtain an mean accuracy of 0.96 with a mean sensitivity and specificity of 0.94 and 0.96 respectively.
Department of Electrical Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark.
Jacob
J
Kempfner
Poul
P
Jennum
Miki
M
Nikolic
Julie A E
JA
Christensen
Helge B D
HB
Sorensen
D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D004585:Electrooculography / Q000379:methods*; D004829:Epilepsy, Generalized / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography / Q000379:methods*; D020923:REM Sleep Parasomnias / Q000175:diagnosis* / Q000503:physiopathology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012895:Sleep, REM