What mAbs tell us about shapes: multiple roads lead to Rome.
In this issue of Immunity, Liao et al. (2013) utilize monoclonal antibodies isolated from RV144 vaccinees to gain key insights into the structural vulnerabilities of the V1-V2 loops of HIV gp120 protein and how they might be associated with vaccine efficacy.
Ragon Institute of MGH, MIT, and Harvard, 149 13(th) Street, Charlestown, MA 02139, USA.
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