Postpartum hypercalcemia secondary to a neuroendocrine tumor of pancreas; a case report and review of literature.
Parathyroid hormone-related protein producing pancreatic neuroendocrine tumors have been infrequently reported. Herein, we report a case of an Iranian woman who had such a tumor during pregnancy, and gave birth to a female neonate with esophago-tracheal fistula and imperforated anus. Hypercalcemia was diagnosed at postpartum because of elevated serum calcium levels in the neonate and neurologic deterioration of the mother. Extensive literature review revealed 42 cases with pancreatic neuroendocrine tumors and hypercalcaemia. The clinical and laboratory findings of such patients are reviewed in this manuscript.
Research Institute for Endocrine Sciences, Taleghani General Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Ali A
AA
Ghazi
Iranpour
I
Boustani
Atieh
A
Amouzegar
Hamid
H
Attarian
Marina
M
Pourafkari
Hossein Nejad
HN
Gashti
Taher
T
Sabetian
Farrokh
F
Tirgari
Siavash
S
Ghazi
Kalman
K
Kovacs
Hypercalcemia; pancreatic tumor; pregnancy