Microvesicles and exosomes as vehicles between protozoan and host cell communication.
Cells release extracellular vesicles in response to external factors or in a physiological way. Microvesicles and exosomes originate in cells in different ways and, depending on their contents, may have multiple biological effects on other cells and the environment. The host cell-parasite relationship could be changed dramatically by the plasticity of a new type of communication through extracellular vesicles. In the present paper, we discuss how protozoans use this new resource to evade the immune system and establish infection.
Laboratorio de Biologia Molecular de Parasitas e Vetores, Instituto Oswaldo Cruz-Fiocruz, Rio de Janeiro, 21040-900, Brazil.
Poliana
P
Deolindo
Ingrid
I
Evans-Osses
Marcel Ivan
MI
Ramirez
D000818:Animals; D002450:Cell Communication; D056890:Eukaryota / Q000276:immunology; D055354:Exosomes; D006790:Host-Parasite Interactions; D006801:Humans; D007113:Immunity, Innate