Development: new wrinkles on genetic control of the MBT.
Three recent studies revise the prevailing view of regulation of the mid-blastula transition in Drosophila, indicating particular requirements for the Cdc25 phosphatase Twine and for zygotic transcription of a specific set of genes.
Department of Biology and Goodman Cancer Research Centre, McGill University, Montréal, Québec, H3G 0B1, Canada. paul.lasko@mcgill.ca
Paul
P
Lasko
D000818:Animals; D001756:Blastoderm / Q000502:physiology*; D002453:Cell Cycle; D018797:Cell Cycle Proteins / Q000378:metabolism*; D004330:Drosophila / Q000196:embryology*; D029721:Drosophila Proteins / Q000378:metabolism*; D004625:Embryo, Nonmammalian / Q000378:metabolism*; D047108:Embryonic Development; D017027:Protein Tyrosine Phosphatases / Q000378:metabolism*; D012319:RNA Polymerase II / Q000378:metabolism*; D016196:S Phase; D020687:cdc25 Phosphatases / Q000378:metabolism*
D018797:Cell Cycle Proteins; D029721:Drosophila Proteins; C075186:twe protein, Drosophila; D012319:RNA Polymerase II; D017027:Protein Tyrosine Phosphatases; D020687:cdc25 Phosphatases; C059217:stg protein, Drosophila