Outbreak of NDM-1-producing Klebsiella pneumoniae in a neonatal unit in Colombia.
Six multiresistant, NDM-1-producing Klebsiella pneumoniae strains were recovered from an outbreak that affected six neonatal patients in a Colombian hospital. Molecular analysis showed that all of the isolates harbored the blaNDM-1, qnrA, and intI1 genes and were clonally related. Multilocus sequence typing showed that the isolates belonged to a new sequence type (ST1043) that was different from the sequence types that had previously been reported. This is the first report of NDM-1-producing isolates in South America.
Bacterial Molecular Genetics Laboratory, Universidad El Bosque, Bogotá, Colombia. labgenmolecular@unbosque.edu.co
Javier Antonio
JA
Escobar Pérez
Narda María
NM
Olarte Escobar
Betsy
B
Castro-Cardozo
Ismael Alberto
IA
Valderrama Márquez
Martha Isabel
MI
Garzón Aguilar
Leslie
L
Martinez de la Barrera
Esther Rocio
ER
Barrero Barreto
Ricaurte Alejandro
RA
Marquez-Ortiz
Maria Victoria
MV
Moncada Guayazán
Natasha
N
Vanegas Gómez
D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D003105:Colombia; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics / Q000502:physiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007710:Klebsiella Infections / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000201:enzymology* / Q000472:pathogenicity*; D008297:Male; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1