Desensitization of allergy to human insulin and its analogs by administering insulin aspart and insulin glargine.
Insulin allergy is a rare clinical situation. We report a 51-year-old patient with type 2 diabetes who required multiple daily insulin injections. The patient developed allergy to human regular insulin and insulin analogs (insulin aspart and insulin glargine), which was resolved by subcutaneous insulin desensitization.
Department of pharmacology, 3rd affiliated hospital, Soochow university, Jiangsu Changzhou, China.
Ping
P
Wu
Cheng
C
Ji
Mingli
M
Wang
Sulan
S
Zou
Weihong
W
Ge
D003888:Desensitization, Immunologic / Q000379:methods*; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000276:immunology; D004334:Drug Administration Schedule; D004342:Drug Hypersensitivity / Q000188:drug therapy*; D006801:Humans; D007328:Insulin / Q000009:adverse effects / Q000031:analogs & derivatives / Q000276:immunology*; D061267:Insulin Aspart / Q000008:administration & dosage*; D000069036:Insulin Glargine; D049528:Insulin, Long-Acting / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged
D007328:Insulin; D049528:Insulin, Long-Acting; D000069036:Insulin Glargine; D061267:Insulin Aspart