Second trimester fetal death caused by varicella-zoster virus infection.
A 31-year-old woman contracted acute varicella at 13 weeks of gestation. Severe hydrops fetalis, hepatomegaly, and intrauterine fetal death were detected at 16 weeks of gestation by ultrasound examinations. An examination at autopsy, histopathology, and polymerase chain reaction (PCR) provided evidence of varicella-zoster virus (VZV) infection of the fetus. Second trimester intrauterine fetal death caused by mother to fetus infection of VZV is extremely rare.
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Kenji
K
Tanimura
Nobue
N
Kojima
Takashi
T
Yamazaki
Shuho
S
Semba
Hiroshi
H
Yokozaki
Hideto
H
Yamada
D000328:Adult; D002644:Chickenpox / Q000150:complications*; D004487:Edema / Q000473:pathology; D005260:Female; D005313:Fetal Death / Q000175:diagnosis*; D006529:Hepatomegaly / Q000473:pathology; D014645:Herpesvirus 3, Human / Q000302:isolation & purification*; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology*; D011262:Pregnancy Trimester, Second