[Intercommunication between bone and central nervous system].
The discovery that leptin regulates bone formation through the central nervous system shed light on a new regulatory system of bone metabolism, i.e., neuronal control. Of note, sympathetic nervous system and parasympathetic nervous system are intimately involved in bone remodeling separately and also in a coordinated manner. Moreover, orexigenic and anorexigenic peptides also regulate bone remodeling in various ways.
Department of Internal Medicine, Keio University, Japan.
Shu
S
Takeda
D000818:Animals; D016723:Bone Remodeling / Q000502:physiology*; D001842:Bone and Bones / Q000378:metabolism*; D002490:Central Nervous System / Q000378:metabolism*; D006801:Humans; D020738:Leptin / Q000378:metabolism; D009479:Neuropeptides / Q000378:metabolism; D010012:Osteogenesis / Q000502:physiology*
D020738:Leptin; D009479:Neuropeptides