5-Iodo-2-aminoindan (5-IAI): chemistry, pharmacology, and toxicology of a research chemical producing MDMA-like effects.
In 2010, an internet snapshot of EMCDDA anticipated the presence of 5-iodo-2-aminoindan (5-IAI) within the recreational drug market. In 2011, this compound, a psychoactive derivative of 2-aminoindane, was identified in recreational products sold in the United Kingdom. 5-IAI is a rigid analogue of p-iodoamphetamine producing MDMA-like effects. The aim of this paper is to summarize the clinical, pharmacological, and toxicological information about this new potential drug of abuse.
Department of Addiction, ASL CN2, Viale Coppino 46, 12051 Alba (CN), Italy. coppolamail@alice.it
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M
Coppola
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R
Mondola
D015104:3,4-Methylenedioxyamphetamine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000633:toxicity; D053593:Forensic Toxicology; D006801:Humans; D013287:Illicit Drugs / Q000737:chemistry / Q000633:toxicity*; D007189:Indans / Q000737:chemistry / Q000633:toxicity*; D015394:Molecular Structure; D015813:Substance Abuse Detection
D013287:Illicit Drugs; D007189:Indans; C008534:MMDA; D015104:3,4-Methylenedioxyamphetamine; C068481:5-iodo-2-aminoindan