Innate lymphoid cells--a proposal for uniform nomenclature.
Innate lymphoid cells (ILCs) are a family of developmentally related cells that are involved in immunity and in tissue development and remodelling. Recent research has identified several distinct members of this family. Confusingly, many different names have been used to characterize these newly identified ILC subsets. Here, we propose that ILCs should be categorized into three groups based on the cytokines that they can produce and the transcription factors that regulate their development and function.
Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. hergen.spits@amc.uva.nl
Hergen
H
Spits
David
D
Artis
Marco
M
Colonna
Andreas
A
Diefenbach
James P
JP
Di Santo
Gerard
G
Eberl
Shigeo
S
Koyasu
Richard M
RM
Locksley
Andrew N J
AN
McKenzie
Reina E
RE
Mebius
Fiona
F
Powrie
Eric
E
Vivier
D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D017408:Guidelines as Topic; D006801:Humans; D007113:Immunity, Innate; D016130:Immunophenotyping; D008214:Lymphocytes / Q000145:classification / Q000276:immunology* / Q000378:metabolism
D015415:Biomarkers