61-year-old man with sudden onset of gross hematuria: a case report.
A 61-year-old man with a medical history of gastroesophageal reflux disease presented with complaints of gross hematuria for 2 days and occasional epistaxis for 1 week. The medication list included only ranitidine. Laboratory data showed significantly elevated prothrombin time and international normalized ratio. The liver panel was normal. On inspection, the patient's bottle of ranitidine, which was refilled 20 days before, contained 5-mg tablets of warfarin. The international normalized ratio and prothrombin time were reversed with FFP, vitamin K, and Novoseven.
1Cook County Emergency Medicine Residency, Chicago, Illinois 2Department of Emergency Medicine, Northshore University Health System, Evanston, Illinois.
Alexander
A
Kogan
Robert
R
Aitchison
Dania S
DS
Lees
Ciro Louis
CL
Landoli
Kristoffer
K
Dayrit
Morris
M
Kharasch
Ernest
E
Wang
D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D000925:Anticoagulants / Q000009:adverse effects; D005764:Gastroesophageal Reflux / Q000150:complications; D006417:Hematuria / Q000209:etiology*; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D019934:International Normalized Ratio; D008297:Male; D019300:Medical Errors; D008875:Middle Aged; D010949:Plasma; D011899:Ranitidine / Q000627:therapeutic use; D014812:Vitamin K / Q000627:therapeutic use; D014859:Warfarin / Q000009:adverse effects
D000897:Anti-Ulcer Agents; D000925:Anticoagulants; D006490:Hemostatics; D014812:Vitamin K; D014859:Warfarin; D011899:Ranitidine