Comparison between two types of local resection in the treatment of ampullary cancer.
BACKGROUND
This study aims to compare the effects of two different local resection procedures on the prognosis of ampullary cancer.


METHODS
We carried out a retrospective study using clinical and pathological data from patients with ampullary cancer who underwent local resection between February 1996 and February 2009 in the PLA General Hospital. In these participants, we carried out a comparative analysis between the transduodenal (the transduodenal group) and the extraduodenal (extraduodenal group) surgical approaches.


RESULTS
No significant differences in gender, age, preoperative bilirubin levels, CA19-9 values, biopsy results, tumour size, differentiation status, degree of invasion, surgical margins, recurrence, metastasis and complication rates, and intraoperative blood loss were found. As compared to the transduodenal group, the extraduodenal group showed a longer duration of surgery and higher survival rates.


CONCLUSIONS
Even though the operation time for the extraduodenal resection of ampullary cancer was longer, the survival rate was higher than in patients who underwent transduodenal resection. For certain patients, the extraduodenal approach may be more appropriate when technical conditions allow it.
Hospital & Institute of Hepatobiliary Surgery, Chinese PLA General Hospital, Beijing, China.
Xiang-Qian
XQ
Zhao
Xiao-Qiang
XQ
Huang
Wen-Zhi
WZ
Zhang
Zhe
Z
Liu
D000368:Aged; D014670:Ampulla of Vater / Q000601:surgery*; D001662:Biliary Tract Surgical Procedures / Q000379:methods*; D003138:Common Bile Duct Neoplasms / Q000401:mortality / Q000601:surgery*; D004386:Duodenum / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome
ampullary cancer; hepatobiliary surgery; local resection; prognosis; retrospective study; transduodenal