Indigenous Dirofilaria immitis in Bangladesh.
Dirofilaria immitis is a parasite of domestic and wild canids and felids in tropical, subtropical and temperate regions throughout the world. The canine heartworm (D. immitis) is the causative agent of canine and feline cardiopulmonary dirofilariasis. This parasite is known to cause a zoonotic disease, namely human pulmonary dirofilariasis. D. immitis is known to be endemic in several South and Southeast Asian countries (e.g. India and Malaysia), but there has previously been no information about the presence of this pathogen in Bangladesh. We present a case of canine dirofilariasis caused by D. immitis in rural southeastern Bangladesh. A male filaroid nematode (95 mm in length and 1.94 mm in width) was identified in the heart of a dog. Species classification was performed by microscopy and molecular tools. Sequence analysis revealed a 100 % identity within the mitochondrial cytochrome c oxidase I (CO1) gene to two Chinese and one Australian D. immitis samples. Usually, dogs stay outside overnight with a high risk to get infected with D. immitis via nocturnal mosquito vectors, which may lead to high prevalences of this pathogen in the canine population and thus increase the risk of human infections with this neglected parasitic disease.
Department of Pathobiology, Institute of Parasitology, University of Veterinary Medicine, Veterinärplatz 1, 1210, Vienna, Austria. hans-peter.fuehrer@vetmeduni.ac.at
Hans-Peter
HP
Fuehrer
Moritz
M
Treiber
Katja
K
Silbermayr
Timo A
TA
Baumann
Paul
P
Swoboda
Anja
A
Joachim
Harald
H
Noedl
D000818:Animals; D001459:Bangladesh; D004183:Dirofilaria immitis / Q000033:anatomy & histology / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D004184:Dirofilariasis / Q000469:parasitology*; D004283:Dog Diseases / Q000469:parasitology*; D004285:Dogs; D003576:Electron Transport Complex IV / Q000235:genetics; D006321:Heart / Q000469:parasitology; D008853:Microscopy; D024101:Mitochondrial Proteins / Q000235:genetics; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA
D024101:Mitochondrial Proteins; D003576:Electron Transport Complex IV