Correlation between intra- and extracranial background EEG.
Scalp EEG is the most widely used modality to record the electrical signals of the brain. It is well known that the volume conduction of these brain waves through the brain, cerebrospinal fluid, skull and scalp reduces the spatial resolution and the signal amplitude. So far the volume conduction has primarily been investigated by realistic head models or interictal spike analysis. We have set up a novel and more realistic experiment that made it possible to compare the information in the intra- and extracranial EEG. We found that intracranial EEG channels contained correlated patterns when placed less than 30 mm apart, that intra- and extracranial channels were partly correlated when placed less than 40 mm apart, and that extracranial channels probably were correlated over larger distances. The underlying cortical area that influences the extracranial EEG is found to be up to 45 cm(2). This area is larger than previously reported.
Technical University of Denmark, Department of Electrical Engineering, Building 349, Oersteds Plads, 2800 Kgs. Lyngby, Denmark. jhe@elektro.dtu.dk
Jonas
J
Duun-Henriksen
Troels W
TW
Kjaer
Rasmus E
RE
Madsen
Line S
LS
Remvig
Carsten E
CE
Thomsen
Helge B D
HB
Sorensen
D000465:Algorithms; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D063132:Connectome / Q000379:methods*; D004569:Electroencephalography / Q000379:methods*; D006801:Humans; D009415:Nerve Net / Q000502:physiology*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013223:Statistics as Topic