An adult case of Fisher syndrome subsequent to Mycoplasma pneumoniae infection.
Reported herein is an adult case of Fisher syndrome (FS) that occurred as a complication during the course of community-acquired pneumonia caused by Mycoplasma pneumoniae. A 38-yr-old man who had been treated with antibiotics for serologically proven M. pneumoniae pneumonia presented with a sudden onset of diplopia, ataxic gait, and areflexia. A thorough evaluation including brain imaging, cerebrospinal fluid examination, a nerve conduction study, and detection of serum anti-ganglioside GQ1b antibody titers led to the diagnosis of FS. Antibiotic treatment of the underlying M. pneumoniae pneumonia was maintained without additional immunomodulatory agents. A complete and spontaneous resolution of neurologic abnormalities was observed within 1 month, accompanied by resolution of lung lesions.
Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea.
So Yeon
SY
Lee
Yong Hoon
YH
Lee
Bo Young
BY
Chun
Shin Yup
SY
Lee
Seung Ick
SI
Cha
Chang Ho
CH
Kim
Jae Yong
JY
Park
Jaehee
J
Lee
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000906:Antibodies / Q000097:blood; D004172:Diplopia / Q000209:etiology; D004906:Erythrocyte Count; D005732:Gangliosides / Q000276:immunology; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D019846:Miller Fisher Syndrome / Q000175:diagnosis* / Q000209:etiology; D011019:Pneumonia, Mycoplasma / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed
D000900:Anti-Bacterial Agents; D000906:Antibodies; D005732:Gangliosides; C039129:GQ1b ganglioside
Anti-GQ1b Antibody; Fisher Syndrome; Mycoplasma pneumoniae