Metal-based methods for protein inactivation.
Metal complexes are efficient catalysts for protein inactivation. Because of their special reactivity, metal-based molecules can achieve results that are difficult, if not impossible to obtain with more traditional, organic-based inhibitors. This article summarizes the chemistry of hydrolytic and oxidative catalysts for protein inactivation.
Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, MI, USA.
Jai
J
Prakash
Jeremy J
JJ
Kodanko
D001671:Biochemistry; D002384:Catalysis; D006801:Humans; D006868:Hydrolysis; D008670:Metals / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D008958:Models, Molecular; D010084:Oxidation-Reduction; D011506:Proteins / Q000037:antagonists & inhibitors* / Q000737:chemistry* / Q000378:metabolism
D008670:Metals; D011506:Proteins