[Morphological changes in autoimmune dacryoadenitis associated with thyroid eye disease].
Increase of lacrimal gland (LG) volume was revealed in 1/3 of patients with thyroid eye disease (TED) using visualization methods. Authors show morphological data confirming development of autoimmune process in LG in TED, biopsy samples were studied within 6 hours after exitus. Specific histomorphological characteristics were analysed considering dystrophic and degenerative changes in LG tissue. Quantitative assessment of fibrosis and vascularization extent is determined using fibrosis and vascularization index.
T N
TN
Safonova
V G
VG
Likhvantseva
K A
KA
Kuz'min
O A
OA
Gontiurova
E I
EI
Rudenko
D001327:Autoimmune Diseases / Q000209:etiology / Q000473:pathology*; D001706:Biopsy; D003607:Dacryocystitis / Q000209:etiology / Q000276:immunology / Q000473:pathology*; D005355:Fibrosis / Q000209:etiology / Q000276:immunology / Q000473:pathology; D049970:Graves Ophthalmopathy / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007765:Lacrimal Apparatus / Q000473:pathology*