Antifungal activity of volatile organic compounds from Streptomyces alboflavus TD-1.
Streptomyces sp. TD-1 was identified as Streptomyces alboflavus based on its morphological characteristics, physiological properties, and 16S rDNA gene sequence analysis. The antifungal activity of the volatile-producing S. alboflavus TD-1 was investigated. Results showed that volatiles generated by S. alboflavus TD-1 inhibited storage fungi Fusarium moniliforme Sheldon, Aspergillus flavus, Aspergillus ochraceus, Aspergillus niger, and Penicillum citrinum in vitro. GC/MS analysis revealed that 27 kinds of volatile organic compounds were identified from the volatiles of S. alboflavus TD-1 mycelia, among which the most abundant compound was 2-methylisoborneol. Dimethyl disulfide was proved to have antifungal activity against F. moniliforme by fumigation in vitro.
Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Engineering and Biotechnology, Tianjin University of Science & Technology, Tianjin, China.
Changlu
C
Wang
Zhifang
Z
Wang
Xi
X
Qiao
Zhenjing
Z
Li
Fengjuan
F
Li
Mianhua
M
Chen
Yurong
Y
Wang
Yufang
Y
Huang
Haiyan
H
Cui
D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001234:Aspergillus niger / Q000187:drug effects / Q000254:growth & development; D001892:Camphanes / Q000737:chemistry / Q000302:isolation & purification; D004220:Disulfides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005670:Fusarium / Q000187:drug effects / Q000254:growth & development; D008401:Gas Chromatography-Mass Spectrometry; D005800:Genes, Fungal; D008826:Microbial Sensitivity Tests; D025282:Mycelium / Q000737:chemistry; D010407:Penicillium / Q000187:drug effects / Q000254:growth & development; D010802:Phylogeny; D012331:RNA, Fungal / Q000032:analysis; D012336:RNA, Ribosomal, 16S / Q000032:analysis; D013172:Spores, Fungal / Q000187:drug effects / Q000254:growth & development; D013302:Streptomyces / Q000737:chemistry* / Q000145:classification / Q000235:genetics; D055549:Volatile Organic Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
D000935:Antifungal Agents; D001892:Camphanes; D004220:Disulfides; D012331:RNA, Fungal; D012336:RNA, Ribosomal, 16S; D055549:Volatile Organic Compounds; C005536:2-methylisoborneol; C021181:dimethyl disulfide