Investigation of an outbreak of osteoarticular infections caused by Kingella kingae in a childcare center using molecular techniques.
We describe an outbreak of 5 osteoarticular infections among 24 daycare center attendees. Polymerase chain reaction revealed Kingella kingae in the joint fluid of 1 child and in 85% of throat samples from healthy contacts. Multilocus sequence typing performed on the joint fluid and carriage isolates identified an unique sequence type. Rifampin failed to eradicate K. kingae carriage.
Univ Paris Diderot, Sorbonne Paris Cité, and AP-HP, Laboratoire de Microbiologie, Hôpital Robert-Debré, Paris, France.
Philippe
P
Bidet
Elodie
E
Collin
Romain
R
Basmaci
Céline
C
Courroux
Véronique
V
Prisse
Véronique
V
Dufour
Edouard
E
Bingen
Emmanuel
E
Grimprel
Stéphane
S
Bonacorsi
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D019072:Antibiotic Prophylaxis; D001170:Arthritis, Infectious / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D002353:Carrier State / Q000382:microbiology; D002656:Child Day Care Centers / Q000706:statistics & numerical data; D004196:Disease Outbreaks; D006801:Humans; D007223:Infant; D017882:Kingella kingae / Q000235:genetics / Q000302:isolation & purification*; D058885:Multilocus Sequence Typing; D016870:Neisseriaceae Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology*; D010019:Osteomyelitis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D010614:Pharynx / Q000382:microbiology; D016133:Polymerase Chain Reaction; D012293:Rifampin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D012293:Rifampin