[Peculiarities of formation, clinical presentations and therapy of diffuse nontoxic goiter of children].
The paper deals with the peculiarities of formation, clinical presentations and therapy of diffuse nontoxic goiter of children. The paper highlights the connection of the disease with the genetic predisposition, the impact of natural and anthropogenic strumagenes, immune processes. The clinical presentations of the diffuse nontoxic goiter are diffuse enlargement of thyroid gland, normal or high level of thyrotropichypophysis hormone when the content of thyroxin and triiodothyronine is normal, which is treated as the subclinic hypothyroidism syndrome. The variety of the disease pathogenesis theories leads to testing of different therapeutic methods, the principal ones among them are the use of iodine preparation and replacement therapy.
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VN
Byriak
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ES
Murashko
D002648:Child; D005260:Female; D020022:Genetic Predisposition to Disease; D006043:Goiter, Endemic / Q000235:genetics / Q000503:physiopathology / Q000628:therapy*; D006044:Goiter, Nodular / Q000235:genetics / Q000503:physiopathology / Q000628:therapy*; D020249:Hormone Replacement Therapy; D006801:Humans; D017613:Iodine Compounds / Q000008:administration & dosage; D008297:Male; D010902:Pituitary Gland / Q000187:drug effects* / Q000378:metabolism / Q000503:physiopathology; D012737:Sex Factors; D013961:Thyroid Gland / Q000187:drug effects* / Q000378:metabolism / Q000503:physiopathology; D013972:Thyrotropin / Q000378:metabolism; D013974:Thyroxine / Q000008:administration & dosage / Q000378:metabolism; D014284:Triiodothyronine / Q000378:metabolism
D017613:Iodine Compounds; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine