A novel phase-corrected 3D cine ultra-short te (UTE) phase-contrast MRI technique.
Phase-contrast (PC) MRI is a non-invasive technique to assess cardiovascular blood flow. However, this technique is not accurate for instance at the carotid bifurcation due to turbulent and disturbed blood flow in atherosclerotic disease. Flow quantification using conventional PC MRI distal to stenotic vessels suffers from intravoxel dephasing and flow artifacts. Previous studies have shown that short echo time (TE) potentially decreases the phase errors. In this work, a novel 3D cine UTE-PC imaging method is designed to measure the blood velocity in the carotid bifurcation using a UTE center-out radial trajectory and short TE time compared to standard PC MRI sequences. With a new phase error correction technique based on autocorrelation method, the proposed 3D cine UTE-PC has the potential to achieve high accuracy for quantification and visualization of velocity jet distal to a stenosis. Herein, we test the feasibility of the method in determining accurate flow waveforms in normal volunteers.
Medical Imaging Lab, Dept. of Electrical and Computer Engineering, University of Louisville, Louisville, KY, United States. m0kadb01@louisville.edu
Mo
M
Kadbi
Hui
H
Wang
Mj
M
Negahdar
Lizette
L
Warner
Melanie
M
Traughber
Peter
P
Martin
Amir A
AA
Amini
D050197:Atherosclerosis / Q000000981:diagnostic imaging / Q000503:physiopathology; D001783:Blood Flow Velocity; D003251:Constriction, Pathologic / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008955:Models, Cardiovascular; D011859:Radiography