Disseminated tuberculosis in a patient with antinuclear antibody-negative systemic lupus erythematosus: a rare association.
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with diverse manifestations. Tuberculosis is known to induce and exacerbate SLE and it becomes quite difficult to diagnose tuberculosis in this setting, owing to a similar, overlapping presentation of tuberculosis and SLE. We report a case of disseminated tuberculosis in a patient with antinuclear antibody-negative SLE. Treatment was started with antitubercular drugs together with hydroxychloroquine and steroid. After 6 months of follow-up the patient recovered with treatment.
Internal Medicine, PGIMER and Dr Ram Manohar Lohia Hospital, New Delhi, India.
Naveen
N
Kumar
Puneet
P
Aggarwal
Nishanth
N
Dev
Gunjan
G
Kumar
D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood*; D018501:Antirheumatic Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy / Q000276:immunology*; D013256:Steroids / Q000627:therapeutic use; D014376:Tuberculosis / Q000150:complications* / Q000188:drug therapy
D000974:Antibodies, Antinuclear; D018501:Antirheumatic Agents; D000995:Antitubercular Agents; D013256:Steroids; D006886:Hydroxychloroquine