Native valve right sided infective endocarditis.
Right-sided infective endocarditis (RSIE) accounts for 5-10% of all cases of infective endocarditis (IE), and is predominantly encountered in the injecting drug user (IDU) population, where HIV and HCV coinfections often coexist. Staphylococcus aureus is the most common pathogen. The pathogenesis of RSIE is still not well understood. RSIE usually presents as a persistent fever with respiratory symptoms whilst signs of systemic embolisation as seen in left-sided IE are notably absent. The prompt diagnosis of RSIE thus requires a high index of suspicion. Transthoracic echocardiography (TTE) can detect the majority of RSIE, whilst transoesophageal echocardiography (TOE) can increase sensitivity. Virulence of the causative organism and vegetation size are the major determinants of prognosis. Most cases of RSIE resolve with appropriate antibiotic administration.
Department of Internal Medicine and Infectious Diseases, University Hospital of Patras, 26504, Rio, Greece. k.akinosoglou07@imperial.ac.uk
Karolina
K
Akinosoglou
Efstratios
E
Apostolakis
Markos
M
Marangos
Geoffrey
G
Pasvol
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D060085:Coinfection; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D015658:HIV Infections / Q000453:epidemiology*; D006349:Heart Valve Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D019698:Hepatitis C, Chronic / Q000453:epidemiology*; D006801:Humans; D011379:Prognosis; D011664:Pulmonary Valve / Q000000981:diagnostic imaging; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D013211:Staphylococcus aureus; D015819:Substance Abuse, Intravenous / Q000453:epidemiology*; D014261:Tricuspid Valve / Q000000981:diagnostic imaging
D000900:Anti-Bacterial Agents
Endocarditis and HIV; Endocarditis in IDU; Pneumonic valve endocarditis; Right sided endocarditis; Tricuspid native valve endocarditis