Impact of vegetarian diet on serum immunoglobulin levels in children.
BACKGROUND
Nutrition plays an important role in immune response. We evaluated the effect of nutrient intake on serum immunoglobulin levels in vegetarian and omnivore children.


METHODS
Serum immunoglobulin levels and iron status were estimated in 22 vegetarian and 18 omnivore children. Seven-day food records were used to assess the diet.


RESULTS
There were no significant differences in serum IgA, IgM, and IgG levels between groups of children. Serum immunoglobulin levels were lower in vegetarian children with iron deficiency in comparison with those without iron deficiency. In the vegetarians, IgG level correlated positively with energy, zinc, copper, and vitamin B(6) intake. In the omnivores, these correlations were stronger with IgM level.


CONCLUSIONS
Despite negligible differences in serum immunoglobulin levels between vegetarian and omnivore children, the impact of several nutrient intakes on IgM and IgG levels differed between groups. Low iron status in vegetarian children can lead to decreased immunoglobulin levels.
3rd Department and Clinic of Paediatrics, Immunology and Rheumaology of Developmental Age, Wroclaw Medical University, 51-149 Wroclaw, Poland. daiva.gorczyca@a.m.wroc.pl
Daiva
D
Gorczyca
Anna
A
Prescha
Karolina
K
Szeremeta
D000293:Adolescent; D000704:Analysis of Variance; D002648:Child; D002675:Child, Preschool; D004032:Diet; D015930:Diet Records; D014676:Diet, Vegetarian; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000097:blood*; D007501:Iron / Q000097:blood*; D008297:Male
D007136:Immunoglobulins; D007501:Iron