Clinical outcomes at 30 days in the Brazilian Registry of Acute Coronary Syndromes (ACCEPT).
BACKGROUND
There are few registries documenting clinical practice in Brazilian patients with acute coronary syndrome.


OBJECTIVE
Demography description, occurrence of major clinical adverse events and comparative analysis in patients submitted or not to an invasive strategy (coronary angiography and myocardial revascularization) in a Brazilian multicenter registry of acute coronary syndrome.


METHODS
The ACCEPT/SBC registry prospectively collected data on acute coronary syndrome patients from 47 Brazilian hospitals. The current analysis reports the occurrence of major clinical outcomes and according to the performance or not of a procedure for myocardial revascularization at the end of 30 day follow-up.


RESULTS
Between August 2010 and December 2011, 2.485 patients were enrolled in this registry. Of these, 31.6% had unstable angina, 34.9% and 33.4% had acute coronary syndrome without and with ST-segment elevation. At 30 days, the performance of a myocardial revascularization procedure was progressively higher according to the severity of clinical presentation (38.7% vs. 53.6% vs. 77.7%, p < 0.001). Cardiac mortality among those submitted or not to myocardial revascularization procedure was 1.0% vs. 2.3% (p = 0.268), 1.9% vs. 4.2% (p = 0.070) and 2.0% vs. 8.1% (p < 0.001), in those with unstable angina, acute coronary syndrome without and with ST-segment elevation, respectively.


CONCLUSIONS
The prescription of a myocardial revascularization procedure was progressively more frequent according to the severity of clinical presentation; for those treated during acute coronary syndrome without and with ST-segment elevation, there was a trend and significant decrease in mortality rate at 30 day of follow-up, respectively.
Sociedade Brasileira de Cardiologia, Rio de Janeiro, Brasil. pivmattos@uol.com.br
Luiz A Lberto
LA
Piva e Mattos
Otávio
O
Berwanger
Elizabete Silva dos
ES
Santos
Helder José Lima
HJ
Reis
Edson Renato
ER
Romano
João Luiz Fernandes
JL
Petriz
Antônio Carlos Sobral
AC
Sousa
Fernando C
FC
Neuenschwander
Jorge Ilha
JI
Guimarães
Jadelson Pinheiro de
JP
Andrade
D054058:Acute Coronary Syndrome / Q000453:epidemiology* / Q000628:therapy; D017677:Age Distribution; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008499:Medical Records / Q000706:statistics & numerical data*; D008875:Middle Aged; D009204:Myocardial Revascularization / Q000706:statistics & numerical data; D011446:Prospective Studies; D012042:Registries / Q000706:statistics & numerical data*; D012307:Risk Factors; D017678:Sex Distribution; D013997:Time Factors; D016896:Treatment Outcome