Frequency-domain optical coherence tomography assessment of very late vascular response after carotid stent implantation.
Intravascular optical coherence tomography is a high-resolution invasive imaging modality that allows the evaluation of vascular responses after stent implantation in a micron-scale level. We describe for the first time two patients with very late vascular response after carotid artery stenting that exhibit two different patterns of low-signal intensity (LSI), "ill-appearing" neointima: the first patient shows layered LSI neointima leading to stent restenosis, coupled with the presence of intraluminal thrombus, whereas the second patient demonstrates another pattern of non-restenotic LSI stent strut coverage, suggestive of lipid laden neointima (ie, "neoatherosclerosis"), recently associated with stent failure in coronary arteries.
Harrington Heart and Vascular Institute, University Hospitals, Case Medical Center, Cleveland, OH 44106, USA.
Guilherme F
GF
Attizzani
Michael R
MR
Jones
Curtis A
CA
Given
William H
WH
Brooks
Hiram G
HG
Bezerra
Marco A
MA
Costa
D000368:Aged; D017130:Angioplasty / Q000009:adverse effects / Q000295:instrumentation*; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000473:pathology*; D016893:Carotid Stenosis / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D058426:Neointima; D058226:Plaque, Atherosclerotic; D011859:Radiography; D012008:Recurrence; D015607:Stents; D013997:Time Factors; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome