Chronic kidney disease: an independent risk factor of all-cause mortality for elderly Chinese patients with chronic heart failure.
OBJECTIVE
To evaluate the prognostic value of chronic kidney disease (CKD) in elderly Chinese patients with chronic heart failure (CHF).


METHODS
The study consisted of 327 elderly patients with CHF. All-cause mortality was chosen as an endpoint over the median follow-up period of 345 days. Cox regression analysis was used to identify the risk factors of mortality.


RESULTS
The median age of the entire cohort was 85 years (60-100 years). The mortality for 168 elderly patients with CHF and CKD (51.4% of entire cohort) was 39.9% (67 deaths), which was higher than the mortality for CHF patients without CKD [25.2% (40/159 deaths)] and the mortality for entire cohort with CHF [32.7% (107/327 deaths)]. The Cox regression analysis showed that old age [hazard ratio (HR): 1.033; 95% confidence interval (95% CI): 1.004-1.064], CKD (HR: 1.705; 95% CI: 1.132-2.567), CHF New York Heart Association (NYHA) class IV (HR: 1.913; 95% CI: 1.284-2.851), acute myocardial infarction (AMI) (HR: 1.696; 95% CI: 1.036-2.777), elevated resting heart rate (HR: 1.021; 95% CI: 1.009-1.033), and decreased plasma albumin (HR: 0.883; 95% CI: 0.843-0.925) were independent risk factors of mortality for elderly patients with CHF.


CONCLUSIONS
CKD was an independent risk factor of mortality for elderly Chinese patients with CHF.
Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing 100853, China.
Shi-Hui
SH
Fu
Bing
B
Zhu
Yu-Xiao
YX
Zhang
Shuang-Yan
SY
Yi
Yuan
Y
Liu
Tie-Hui
TH
Xiao
Liang
L
Wang
Yong-Yi
YY
Bai
Cai-Yi
CY
Lu
Ping
P
Ye
Lei-Ming
LM
Luo
Chronic heart failure; Chronic kidney disease; Risk factor; The aged