Insulin resistance and glucose and lipid concentrations in a cohort of perinatally HIV-infected Latin American children.
We measured glucose, insulin and lipids in 249 perinatally HIV-infected Latin American children. Only 1 subject had impaired fasting glucose; 6.8% had insulin resistance. Abnormalities in total, low-density lipoprotein and high-density lipoprotein cholesterol and triglycerides were reported for 13%, 13%, 21% and 34%, respectively. Continued follow-up of this population is necessary to characterize the evolution and clinical consequences of these findings.
Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892–7510, USA. hazrar@mail.nih.gov
Rohan
R
Hazra
Laura Freimanis
LF
Hance
Jacqueline Pontes
JP
Monteiro
Noris Pavia
NP
Ruz
Daisy Maria
DM
Machado
Mariza
M
Saavedra
Fabrizio
F
Motta
D Robert
DR
Harris
D001786:Blood Glucose / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007333:Insulin Resistance; D007843:Latin America / Q000453:epidemiology; D008055:Lipids / Q000097:blood*; D008297:Male; D011446:Prospective Studies
D001786:Blood Glucose; D008055:Lipids