Quality control: putting protein aggregates in a bind.
Asymmetric inheritance of protein aggregates in budding yeast is a fascinating yet controversial area of aging research. A recent study demonstrates that unfolded protein aggregates are confined to the mother by tethering to organelles rather than retrograde transport.
Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.
Jay R
JR
Unruh
Brian D
BD
Slaughter
Rong
R
Li
D060049:Asymmetric Cell Division; D005656:Fungal Proteins / Q000502:physiology*; D040582:Inheritance Patterns / Q000502:physiology*; D004718:Saccharomycetales / Q000502:physiology*
D005656:Fungal Proteins