Ciprofloxacin-resistant Aeromonas hydrophila cellulitis following leech therapy.
We report a case of surgical site infection with ciprofloxacin-resistant Aeromonas hydrophila following leech therapy. Antimicrobial and genetic analyses of leech and patient isolates demonstrated that the resistant isolates originated from the leech gut microbiota. These data suggest that ciprofloxacin monotherapy as a prophylaxis regimen prior to leech therapy may not be effective in preventing infection.
David Geffen School of Medicine, Department of Pathology, University of California, Los Angeles, California, USA.
Carmen L
CL
Giltner
April M
AM
Bobenchik
Daniel Z
DZ
Uslan
Jaime G
JG
Deville
Romney M
RM
Humphries
D016980:Aeromonas hydrophila / Q000187:drug effects / Q000302:isolation & purification*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002481:Cellulitis / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D002648:Child; D002939:Ciprofloxacin / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial; D005260:Female; D041981:Gastrointestinal Tract / Q000382:microbiology; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D047709:Hirudo medicinalis / Q000382:microbiology; D006801:Humans; D024763:Leeching / Q000009:adverse effects*; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology
D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin