Associations of health literacy with dialysis adherence and health resource utilization in patients receiving maintenance hemodialysis.
BACKGROUND
Although limited health literacy is common in hemodialysis patients, its effects on clinical outcomes are not well understood.


METHODS
Observational study.


METHODS
260 maintenance hemodialysis patients enrolled in a randomized clinical trial of symptom management strategies from January 2009 through April 2011.


METHODS
Limited health literacy.


RESULTS
Dialysis adherence (missed and abbreviated treatments) and health resource utilization (emergency department visits and end-stage renal disease [ESRD]-related hospitalizations).


METHODS
We assessed health literacy using the Rapid Estimate of Adult Literacy in Medicine (REALM) and used negative binomial regression to analyze the independent associations of limited health literacy with dialysis adherence and health resource utilization over 12-24 months.


RESULTS
41 of 260 (16%) patients showed limited health literacy (REALM score, ≤60). There were 1,152 missed treatments, 5,127 abbreviated treatments, 552 emergency department visits, and 463 ESRD-related hospitalizations. Limited health literacy was associated independently with an increased incidence of missed dialysis treatments (missed, 0.6% vs 0.3%; adjusted incidence rate ratio [IRR], 2.14; 95% CI, 1.10-4.17), emergency department visits (annual visits, 1.7 vs 1.0; adjusted IRR, 1.37; 95% CI, 1.01-1.86), and hospitalizations related to ESRD (annual hospitalizations, 0.9 vs 0.5; adjusted IRR, 1.55; 95% CI, 1.03-2.34).


CONCLUSIONS
Generalizability and potential for residual confounding.


CONCLUSIONS
Patients receiving maintenance hemodialysis who have limited health literacy are more likely to miss dialysis treatments, use emergency care, and be hospitalized related to their kidney disease. These findings have important clinical practice and cost implications.
Nephrology Department, Geisinger Medical Center, Danville, PA, USA. jgreen1@geisinger.edu
Jamie A
JA
Green
Maria K
MK
Mor
Anne Marie
AM
Shields
Mary Ann
MA
Sevick
Robert M
RM
Arnold
Paul M
PM
Palevsky
Michael J
MJ
Fine
Steven D
SD
Weisbord
D000368:Aged; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D057220:Health Literacy; D006295:Health Resources / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D011446:Prospective Studies; D006435:Renal Dialysis / Q000706:statistics & numerical data*