[Investigation of articular cavity medicating for treatment of knee osteoarthritis].
Osteoarthritis (OA) is a common chronic progressing disease in the elderly. In current there are many methods of drug treatment for knee osteoarthritis, the intra-articular injection belongs to local application, can direct effect on arthritis, is the most used and most effective methods in osteoarthritis treatment. A single medication may exist that anti-inflammatory effects produce a marked effect but articular cartilage injury is induced, or articular cartilage repairing are promoted but anti-inflammatory effects is not ideal. Therefore,the best method of treatment should be a comprehensive analysis of articular structure, function and possible pathogenic factor to understand the expectations of level of recovery and use in patients to design an individualized treatment plan.
Department of Orthopaedics, Nanjing General Hospital of Nanjing Military Command of PLA, Nanjing 210000, Jiangsu, China.
Cheng-Long
CL
Liu
Ting
T
Guo
Jian-Ning
JN
Zhao
D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007270:Injections, Intra-Articular; D009019:Morphinans / Q000627:therapeutic use; D020370:Osteoarthritis, Knee / Q000188:drug therapy*
D005938:Glucocorticoids; D009019:Morphinans; C009271:sinomenine