Langerhans cell histiocytosis: a diagnostic dilemma.
Langerhans cell histiocytosis (LCH) is a rare clonal neoplastic disorder of unknown aetiology which can present with a diverse range of clinical presentations. It encompasses a diverse number of idiopathic conditions which can involve multiple body systems and is characterized by bone marrow-derived Langerhans cell proliferation. The disease can affect multiple body systems and lesions can be solitary or widespread. We present a case of a multifocal eosinophilic granuloma (LCH) in a young adult female with clinical signs and symptoms similar to aggressive periodontitis.


CONCLUSIONS
Langerhans cell histiocytosis is a rare disease which can have a similar clinical presentation to aggressive periodontitis.
Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Turner Street, London, UK.
Paul L
PL
Ryan
Kim M
KM
Piper
Francis J
FJ
Hughes
D000328:Adult; D010520:Aggressive Periodontitis / Q000175:diagnosis; D003937:Diagnosis, Differential; D004803:Eosinophilic Granuloma / Q000473:pathology*; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology*; D006801:Humans; D008339:Mandibular Neoplasms / Q000473:pathology*