Parameter estimation of the Huxley cross-bridge muscle model in humans.
The Huxley model has the potential to provide more accurate muscle dynamics while affording a physiological interpretation at cross-bridge level. By perturbing the wrist at different velocities and initial force levels, reliable Huxley model parameters were estimated in humans in vivo using a Huxley muscle-tendon complex. We conclude that these estimates may be used to investigate and monitor changes in microscopic elements of muscle functioning from experiments at joint level.
Biomechanical Engineering of the Delft University of Technology, Delft, The Netherlands. a.n.vardy@tudelft.nl
Alistair N
AN
Vardy
Erwin
E
de Vlugt
Frans C T
FC
van der Helm
D000465:Algorithms; D003198:Computer Simulation; D005260:Female; D006801:Humans; D008297:Male; D008954:Models, Biological; D009119:Muscle Contraction / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology*; D016059:Range of Motion, Articular / Q000502:physiology*; D013710:Tendons / Q000502:physiology*; D014955:Wrist Joint / Q000502:physiology*