Decontamination with chlorhexidine gluconate reduces the incidence of ventilator associated pneumonia.
Ventilator-associated pneumonia is a major source of nosocomical infection affecting about 27 percent of all critically ill patients. In this study, an attempt was made to assess the effect of oral decontamination with 0.2% chlorhexidine gluconate solution and hydrogen peroxide solution on the incidence of ventilator-associated pneumonia and oropharyngal colonisation. Seventy patients above 18 years of age admitted in AIIMS, New Delhi were included as subjects. It was concluded that incidence of ventilator-associated pneumonia was higher in patients given oral care with hydrogen peroxide than those on 0.2% chlorhexidine, which was more effective in reducing orophyryngeal colonisation.
College of Nursing, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
Ujjwal
U
Dahiya
D000284:Administration, Oral; D000328:Adult; D002710:Chlorhexidine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D003428:Cross Infection / Q000453:epidemiology / Q000517:prevention & control*; D003666:Decontamination / Q000379:methods*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D009067:Mouthwashes / Q000008:administration & dosage / Q000494:pharmacology*; D053717:Pneumonia, Ventilator-Associated / Q000453:epidemiology / Q000517:prevention & control*
D009067:Mouthwashes; C010882:chlorhexidine gluconate; D002710:Chlorhexidine