Epidemiology and trend of neurological diseases associated to HIV/AIDS. Experience of Mexican patients 1995-2009.
OBJECTIVE
The aim of this study was to identify the main neurological conditions associated with HIV/AIDS in Mexican patients treated at the National Institute of Neurology and Neurosurgery (NINN) in Mexico city, the main referral center for patients with disorders of the central and peripheral nervous system.


METHODS
An observational, transversal and descriptive analysis was performed. We reviewed the databases from the Department of Epidemiology and the medical records of patients with AIDS seen during the period from January 1st, 1995 to December 31, 2009.


RESULTS
320 patients were detected, the main conditions related to HIV/AIDS were brain toxoplasmosis (42%), cerebral criptoccocosis (28%), tuberculous meningitis (8.7%), linfoma no Hodking (3.75%), acute HIV infection (3.4%) and AIDS dementia complex (3%). No specific trend on morbility and mortality were detected during the period of study.


CONCLUSIONS
In Mexico the most common neurological complications of HIV/AIDS are opportunistic infections.
Department of Epidemiology, National Institute of Neurology and Neurosurgery, Manuel Velasco Suárez, Insurgentes Sur 3877, Tlalpan 14269, Mexico city, Mexico. mantonietarc@yahoo.com.mx
M A
MA
Ramírez-Crescencio
L
L
Velásquez-Pérez
María Antonieta
MA
Ramírez-Crescencio
Leora
L
Velásquez-Pérez
D015526:AIDS Dementia Complex / Q000453:epidemiology; D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000453:epidemiology; D000163:Acquired Immunodeficiency Syndrome; D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D003389:Cranial Nerve Diseases / Q000453:epidemiology / Q000209:etiology; D004522:Educational Status; D004651:Employment; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology* / Q000401:mortality; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D009422:Nervous System Diseases / Q000453:epidemiology* / Q000209:etiology*; D010523:Peripheral Nervous System Diseases / Q000453:epidemiology / Q000209:etiology; D012737:Sex Factors; D012959:Socioeconomic Factors; D014057:Tomography, X-Ray Computed; D016781:Toxoplasmosis, Cerebral / Q000453:epidemiology / Q000209:etiology; D055815:Young Adult
Brain toxoplasmosis; Epidemiology; HIV/AIDS; Meningeal cryptococcosis; Mexico; Neurological disease; Trends