Rebelliousness in patients suffering from schizophrenia-spectrum disorders--a possible predictor of attitudes towards medication.
The inclusive trait of rebelliousness has a proven role both in development and in the understanding of non-psychotic psychopathologies. The present study focused on evaluating rebelliousness levels and their possible correlation with the attitude towards medication among patients suffering from schizophrenia-spectrum disorders. Patient suffering from schizophrenia-spectrum disorders (n=75) and non-psychotic disorders (n=53) underwent a thorough clinical evaluation. The attitude towards medication was evaluated using the Drug Attitude Inventory (DAI-10), and levels of rebelliousness via the validated rebelliousness scale. Rebelliousness was also assessed in an additional control group (n=64). A significant negative correlation between levels of rebelliousness and the attitude towards medication was found uniquely in the schizophrenia group (r=-0.434, p<0.001). In a regression model rebelliousness levels were found to be the strongest predictor of the attitude towards medication ((β=-0.434, p<0.01)) compared with other demographic variables such as drug abuse (β=-0.256, p<0.05) and involuntary treatment (β=0.236, p<0.05). The intriguing correlation between rebelliousness and drug attitude (as an indicator of adherence) should be further studied in additional longitudinal prospective studies.
Shalvata Mental Health Care Center, Hod-Hasharon, Israel; Sackler School of Medicine, Tel Aviv University, Ramat Aviv, Tel Aviv, Israel. Electronic address: urinitzan@walla.co.il.
Uri
U
Nitzan
Gabriel
G
Bukobza
Shai
S
Aviram
Shmuel
S
Fennig
Shaul
S
Lev-Ran
Yoram
Y
Braw
Yuval
Y
Bloch
D000328:Adult; D000704:Analysis of Variance; D001294:Attitude to Health; D005260:Female; D006801:Humans; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D019964:Mood Disorders / Q000175:diagnosis / Q000209:etiology* / Q000523:psychology; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000150:complications*; D012565:Schizophrenic Psychology; D012959:Socioeconomic Factors; D013223:Statistics as Topic; D011795:Surveys and Questionnaires; D055815:Young Adult
Adherence; Compliance; Drug; Schizophrenia