Imaging and percutaneous occlusion of a large aneurysm of the ductus arteriosus in an infant with Loeys-Dietz syndrome.
Loeys-Dietz is a multisystem congenital syndrome that comprises craniofacial and cutaneous abnormalities as well as structural cardiac defects. One of its key pathological features is an aggressive widespread vasculopathy that can manifest as aortic or cerebral aneurysms, which is prone to dissection and rupture. We report a case of a large aneurysm of the ductus arteriosus in a patient with Loeys-Dietz syndrome, successfully occluded by interventional catheterization.
Department of Cardiology, Bristol Royal Hospital for Children, Bristol, United Kingdom.
Gareth J
GJ
Morgan
Deane L S
DL
Yim
Alison M
AM
Hayes
Robin P
RP
Martin
Mark C K
MC
Hamilton
Graham
G
Stuart
D000783:Aneurysm / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy*; D001027:Aortography / Q000379:methods*; D006328:Cardiac Catheterization / Q000295:instrumentation; D004373:Ductus Arteriosus / Q000000981:diagnostic imaging*; D006331:Heart Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy*; D006801:Humans; D007223:Infant; D055947:Loeys-Dietz Syndrome / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D008297:Male; D011237:Predictive Value of Tests; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
Amplatzer; Ductal Aneurysm; Loeys-Dietz; Transcatheter Closure; losartan