[The role of disbalance of zinc and copper in school age children with community-aquired pheumonia].
The article analyzed 60 patients with community-aquired pneumonia from ages 6 to 18 years. The dependences of trace levels of zinc and copper in the serum of these children on the activity of the inflammatory process. Analysis of survey results showed that in children with community-aquired pneumonia was observed imbalance of trace elements Zn, Cu. Severity of such violations depended mainly on severity disease and to a lesser extent on age. Normalization of detected metabolic microelement content in a period of convalescence practically advancing. In children at acute stage of community-aquired pneumonia inflammation was observed with pronounced zinc deficiency (P < 0,001), and its content in blood serum is directly dependent on the acuity and severity of inflammation. Use of the drug, which contains zinc as part of adjuvant therapy in community-aquired pneumonia in children led to more rapid normalization of serum microelement parameters, apparently due to modulating effects on microelement status and immune status. To increase the effectiveness of treatment of community-aquired pneumonia in school-age children, its recommended to use zinc containing drug.
O I
OI
Smian
V A
VA
Horbas'
T P
TP
Bynda
O P
OP
Moshchych
P I
PI
Sichnenko
O K
OK
Romaniuk
O H
OH
Vasyl'ieva
A O
AO
Potapova
D000293:Adolescent; D002648:Child; D017714:Community-Acquired Infections; D003300:Copper / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D011014:Pneumonia / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D012720:Severity of Illness Index; D013334:Students; D014883:Water-Electrolyte Imbalance / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D015032:Zinc / Q000097:blood* / Q000172:deficiency; D019287:Zinc Sulfate / Q000494:pharmacology / Q000627:therapeutic use*
D019287:Zinc Sulfate; D003300:Copper; D015032:Zinc