[Stability of PEGylated puerarin under different storage conditions].
OBJECTIVE
To detect the stability of PEGylated puerarin (PEG-PUE), in order to provide experimental basis for storage conditions of PEGylated puerarin.


METHODS
First, a method for determining the content of PEG-PUE was established. Next, a system study was conducted for the stability of PEG-PUE affected by different factors such as temperature, humidity, light and light avoidance.


RESULTS
PEG-PUE was severely degraded under the conditions of high temperature, high humidity and light. It was also seriously degraded under high temperature.


CONCLUSIONS
PEG-PUE shall be stored under low temperature and in a dark and dry environment.
Key Research Laboratory for Development of New Drugs, The Second Xiangya Hospital of Central South University, Changsha 410013, China. liuxinyi128@126.com
Xin-Yi
XY
Liu
Da-Xiong
DX
Xiang
Jian-He
JH
Li
Xiong-Bin
XB
Hu
Zu-Guang
ZG
Ye
D004355:Drug Stability; D004356:Drug Storage; D007529:Isoflavones / Q000737:chemistry*; D008027:Light; D011092:Polyethylene Glycols / Q000737:chemistry*; D013696:Temperature
D007529:Isoflavones; D011092:Polyethylene Glycols; C033607:puerarin