Maxillary rhinosinusitis due to Fusarium species leading to cavernous sinus thrombosis.
Fungal rhinosinusitis is being recognized and reported with increasing frequency over the last two decades worldwide. Intracranial extension is the most dreaded complication of fungal sinusitis with high mortality rates. We report a case of chronic rhinosinusitis in a 55-year-old diabetic male, caused by Fusarium species. The patient was diagnosed as a case of chronic left maxillary sinusitis with cavernous sinus thrombosis. The sinus lavage showed fungal elements on direct microscopic examination and culture revealed growth of Fusarium species within 4 days of incubation. Conservative therapy with IV amphotericin B resulted in favorable outcome of the patient. This is an extremely rare case where cavernous sinus thrombosis occurred as a complication secondary to Fusarium species rhinosinusitis.
Department of Microbiology, KIMSU, Karad, 415110 Maharashtra, India. drvsrajmane@yahoo.com
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D000666:Amphotericin B / Q000627:therapeutic use; D020226:Cavernous Sinus Thrombosis / Q000175:diagnosis / Q000209:etiology*; D002439:Cefotaxime / Q000627:therapeutic use; D002908:Chronic Disease; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy; D004172:Diplopia / Q000209:etiology; D004198:Disease Susceptibility; D060585:Fusariosis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D005670:Fusarium / Q000254:growth & development / Q000302:isolation & purification*; D006261:Headache / Q000209:etiology; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D015523:Maxillary Sinusitis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D008875:Middle Aged; D020795:Photophobia / Q000209:etiology; D012220:Rhinitis / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D014839:Vomiting / Q000209:etiology
D007328:Insulin; D000666:Amphotericin B; D002439:Cefotaxime