[Endophthalmitis in course of candidosis--a case report].
OBJECTIVE
Description of a rare case of bilateral fungal endophthalmitis in a patient and the associated diagnostic and therapeutic difficulties.


METHODS
Patient 28 years old was diagnosed because of bilateral deterioration in endophthalmitis. Therefore, the diagnostic possibilities were run down and material taken from the vitreous chamber were handed to determine the Candida spp. antigen using Elisa test, standardized for serum and cerebrospinal fluid. Combination therapy including drugs and surgery were performed.


RESULTS
Ophthalmoscopy OP/OL showed the presence of "clusters of cotton" in vitreous body characteristic for ocular candidosis. Targeted treatment for Candida spp. with voriconazole were based on a very high concentration of mannan antigen in the resulting of the test. The final diagnosis was established after microbiological examination of material taken during vitrectomy.


CONCLUSIONS
High level of mannan antigen Candida spp 4259.83 in vitreous body may indicate a fungal endophthalmitis. fungal endophthalmitis, ocular candidosis, endogenic infection of the eye.
Katedra i Klinika Okulistyki Pomorskiego Uniwersytetu Medycznego w Szczecinie. kot_joanna@wp.pl
Joanna
J
Kot
Zaneta
Z
Borowiec-Chłopek
Ewelina
E
Lachowicz
Stefania
S
Giedrys-Kalemba
Damian
D
Czepita
Danuta
D
Karczewicz
D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage; D002177:Candidiasis / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D009877:Endophthalmitis / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D015821:Eye Infections, Fungal / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D006801:Humans; D008297:Male; D011743:Pyrimidines / Q000008:administration & dosage; D016896:Treatment Outcome; D014230:Triazoles / Q000008:administration & dosage; D014821:Vitrectomy; D065819:Voriconazole
D000935:Antifungal Agents; D011743:Pyrimidines; D014230:Triazoles; D065819:Voriconazole