Effects of exposure to a 50 Hz sinusoidal magnetic field during the early adolescent period on spatial memory in mice.
Adolescence is a critical developmental stage during which substantial remodeling occurs in brain areas involved in emotional and learning processes. Although a robust literature on the biological effects of extremely low frequency magnetic fields (ELF-MFs) has been documented, data on the effects of ELF-MF exposure during this period on cognitive functions remain scarce. In this study, early adolescent male mice were exposed from postnatal day (P) 23-35 to a 50 Hz MF at 2 mT for 60 min/day. On P36-45, the potential effects of the MF exposure on spatial memory performance were examined using the Y-maze and Morris water maze tasks. The results showed that the MF exposure did not affect Y-maze performance but improved spatial learning acquisition and memory retention in the water maze task under the present experimental conditions.
Laboratory of Primate Neuroscience Research, Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, PR China.
Xiusong
X
Wang
Ke
K
Zhao
Dong
D
Wang
Wendy
W
Adams
Yu
Y
Fu
Huaying
H
Sun
Xiaofen
X
Liu
Hualin
H
Yu
Yuanye
Y
Ma
D000818:Animals; D049628:Body Size; D048788:Growth and Development; D060526:Magnetic Fields / Q000009:adverse effects*; D008297:Male; D018782:Maze Learning / Q000502:physiology; D008568:Memory; D051379:Mice; D013037:Spatial Behavior / Q000502:physiology*