Unsuccessful planned conservative resection of placental site trophoblastic tumor.
BACKGROUND
Placental site trophoblastic tumor is a rare subtype of gestational trophoblastic neoplasia affecting women of reproductive age. The preferred method of treatment is surgical resection.


METHODS
A 33-year-old woman, gravida 3 para 1111, was incidentally diagnosed with placental site trophoblastic tumor during an evaluation for infertility. As a result of persistent pathologic evidence of disease, she underwent a hysterectomy. The site of disease on pathologic review of the hysterectomy specimen was widely discordant from the preoperative imaging and hysteroscopic evaluations.


CONCLUSIONS
Wedge resection of the uterus has been suggested as an acceptable alternative to hysterectomy in women with placental site trophoblastic tumor who wish to preserve future fertility. However, this case demonstrated that preoperative imaging may not correlate with the tumor site, making wedge resection treatment ineffective.
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York 10021, USA. jolynstaylor@gmail.com
Jolyn S
JS
Taylor
Luciana
L
Viera
Thomas A
TA
Caputo
Joanna
J
Chan
Melissa K
MK
Frey
Divya
D
Gupta
Isaac
I
Kligman
D000328:Adult; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis / Q000601:surgery*; D018245:Trophoblastic Tumor, Placental Site / Q000175:diagnosis / Q000601:surgery*; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000601:surgery*