Long-term results of deep sclerectomy with small collagen implant in Korean.
OBJECTIVE
To describe the long-term results of deep sclerectomy with collagen implant (DSCI) with or without adjuvant mitomycin C in Korean patients with primary or secondary open-angle glaucoma (OAG).


METHODS
This retrospective review was comprised of 65 Korean patients who received DSCI with or without adjuvant mitomycin C due to primary or secondary OAG. Patients were followed for 72 months after surgery. Complete success was defined as intraocular pressure (IOP) <21 mmHg without medication and qualified success was defined as IOP <21 mmHg with or without medication.


RESULTS
Mean postoperative follow-up period was 53.0 ± 16.2 months. Mean IOP was 30.5 ± 11.7 mmHg preoperatively, 8.4 ± 4.3 mmHg at postoperative day one and 13.4 ± 3.8 mmHg 60 months after surgery. The mean number of glaucoma medications was decreased from 3.6 ± 1.1 to 1.6 ± 1.3 at 60 months after the operation. Complete and qualified success rates were 36.7% and 79.6% at postoperative 60 months, respectively (Kaplan-Meier survival curve). No shallow or flat anterior chamber, endophthalmitis, or surgery-induced significant cataract was observed.


CONCLUSIONS
The results of DSCI in Korean patients presented here seem reasonably excellent with qualified success rates of over 70% at six years with negligible complications.
Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.
Seungsoo
S
Rho
Sung Yong
SY
Kang
Samin
S
Hong
Gong Je
GJ
Seong
Jong Jin
JJ
Jung
Chan Yun
CY
Kim
D000328:Adult; D000867:Anterior Chamber / Q000601:surgery*; D003094:Collagen / Q000008:administration & dosage*; D004343:Drug Implants / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D015994:Incidence; D007429:Intraocular Pressure; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D011184:Postoperative Period; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D012590:Sclera / Q000601:surgery*; D012599:Sclerostomy / Q000379:methods*; D013997:Time Factors; D016896:Treatment Outcome; D014792:Visual Acuity
D004343:Drug Implants; D003094:Collagen
Deep sclerectomy; Koreans; Open-angle glaucoma; Small collagen implant