A new trend on biosensor for neurotransmitter choline/acetylcholine--an overview.
Technology always has been an indispensible part in the development of biosensors. The performance of biosensors is being tremendously improved using new materials as transducer as well as binding material in their construction. The use of new materials allowed innovation on transduction technology in biosensor preparations. Because of the submicron dimensions of these sensors, simple and rapid analyses in vitro as well as in vivo are now possible. Portable instruments capable of analysing multiple components are becoming available, too. Sensors that provide excellent temporal and spatial resolution for in vivo monitoring such as for measurement of neurotransmitters have become prominent. The interest to improve the stability, sensitivity and selectivity of the sensors is paramount. This study tries to give an overview of the present status of the material-based biosensor design and new generation of choline/acetylcholine neurotransmitter biosensors.
Chemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia. anishkhan97@gmail.com
Anish
A
Khan
Aftab Aslam Parwaz
AA
Khan
Abdullah M
AM
Asiri
Malik Abdul
MA
Rub
Naved
N
Azum
Mohammed M
MM
Rahman
Sher Bahadar
SB
Khan
Sulaiman Ab
SA
Ghani
D000109:Acetylcholine / Q000378:metabolism*; D000818:Animals; D015374:Biosensing Techniques / Q000191:economics / Q000379:methods*; D001921:Brain / Q000378:metabolism; D002794:Choline / Q000378:metabolism*; D006801:Humans; D018377:Neurotransmitter Agents / Q000378:metabolism*
D018377:Neurotransmitter Agents; D002794:Choline; D000109:Acetylcholine