Multidetector CT Dentascan evaluation of bone regeneration obtained with deproteinised bovine graft in residual cavity after mandibular cyst enucleation.
OBJECTIVE
This study compared spontaneous bone healing and regeneration obtained with deproteinised bovine graft in residual cavities after mandibular cyst enucleation using computed tomography (CT) Dentascan.


METHODS
Eighty patients with a radiological diagnosis of mandibular cyst underwent surgical enucleation. Patients were divided into a control group (spontaneous healing, 40 patients) and a test group (deproteinised bovine graft, 40 patients). All patients underwent follow-up CT Dentascan 12 months after the procedure. For each residual cavity, apical-coronal and mesial-distal distance, average pixel intensity and volume were calculated and results compared between two groups using the t test.


RESULTS
The control group showed mean volume, apical-coronal and mesial-distal distance of 703.2 ± 185.3 mm(3), 28.6 ± 9.4 mm and 25 ± 2.84 mm, respectively. In the test group, values were 738.2 ± 189.2 mm(3), 27.5 ± 3.6 mm and 25.3 ± 2.97 mm, respectively. There was no statistically significant difference between groups. Average pixel intensity was 1,102.8 ± 124.3 in the test group and 624.9 ± 133.3 in the control group, with a significant difference between groups (p<0.0001).


CONCLUSIONS
The significantly higher average pixel intensity observed in the test group demonstrates the cavalue of treatment with biomaterials to obtain earlier bone regeneration.
Dipartimento di Specialità Medico-Chirurgiche-Chirurgia Orale, Azienda Ospedaliero Universitaria Policlinico-Vittorio Emanuele, PO G Rodolico, Via Santa Sofia 78, 95123 Catania, Italy. sabr.pappalardo@tiscali.it
S
S
Pappalardo
M
M
Coronella
M L
ML
Lanza
V
V
Rabbito
P V
PV
Foti
L A
LA
Mauro
S
S
Palmucci
G C
GC
Ettorre
D000328:Adult; D000818:Animals; D001845:Bone Cysts / Q000000981:diagnostic imaging* / Q000601:surgery*; D001861:Bone Regeneration; D018786:Bone Substitutes; D016022:Case-Control Studies; D002417:Cattle; D005260:Female; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000000981:diagnostic imaging* / Q000601:surgery*; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D011446:Prospective Studies; D011857:Radiographic Image Interpretation, Computer-Assisted; D016896:Treatment Outcome; D014945:Wound Healing
D018786:Bone Substitutes