A successful switch from transdermal fentanyl to transdermal buprenorphine in a patient with neuropathic pain: a case report.
Buprenorphine is a frequently used opioid in the treatment of neuropathic pain component that is often present in patients with cancer. A case of a 41-year-old patient was depicted whose pain syndrome was associated with the chondrosarcoma growth originating from the sacral bone and numerous surgical interventions and radiotherapy. Improvement in analgesia and good toleration of therapy were observed after switching from transdermal fentanyl to transdermal buprenorphine while maintaining treatment with antidepressants and anticonvulsants. This case report indicates a possibility of a safe switch of transdermal opioids at home, which may provide benefits in terms of analgesia and adverse effects and in consequence have positive impact on the patients' quality of life. This is also accompanied by constant psychological, social, and spiritual support provided to the patient and family.
1Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland.
Wojciech
W
Leppert
D000279:Administration, Cutaneous; D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000627:therapeutic use; D002047:Buprenorphine / Q000008:administration & dosage* / Q000627:therapeutic use; D057915:Drug Substitution / Q000379:methods*; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D009437:Neuralgia / Q000188:drug therapy*; D010166:Palliative Care; D011788:Quality of Life
D000701:Analgesics, Opioid; D002047:Buprenorphine; D005283:Fentanyl
analgesia; neuropathic pain; opioid switch; transdermal buprenorphine; transdermal fentanyl; treatment