Facile incorporation of aggregation-induced emission materials into mesoporous silica nanoparticles for intracellular imaging and cancer therapy.
Aggregation-induced emission (AIE) materials were facilely incorporated into mesoporous silica nanoparticles (MSNs) via one-pot surfactant templated method. Cell imaging and cancer therapy applications of such fluorescent MSNs were further explored. We demonstrated that AIE-MSN nanocomposites showed strong fluorescence and uniform morphology, making them promising for both cell imaging and cancer therapy.
Department of Chemistry and the Tsinghua Center for Frontier Polymer Research, Tsinghua University, Beijing, 100084, PR China.
Xiaoyong
X
Zhang
Xiqi
X
Zhang
Shiqi
S
Wang
Meiying
M
Liu
Yun
Y
Zhang
Lei
L
Tao
Yen
Y
Wei
D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D018613:Microscopy, Confocal; D053758:Nanoparticles / Q000737:chemistry / Q000627:therapeutic use*; D009369:Neoplasms / Q000175:diagnosis / Q000188:drug therapy; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry
D013501:Surface-Active Agents; D012822:Silicon Dioxide