College of American Pathologists Gynecologic Cytopathology Quality Consensus Conference on good laboratory practices in gynecologic cytology: background, rationale, and organization.
BACKGROUND
Gynecologic cytopathology is a heavily regulated field, with Clinical Laboratory Improvement Amendments of 1988 mandating the collection of many quality metrics. There is a lack of consensus regarding methods to collect, monitor, and benchmark these data and how these data should be used in a quality assurance program. Furthermore, the introduction of human papilloma virus testing and proficiency testing has provided more data to monitor.


OBJECTIVE
To determine good laboratory practices in quality assurance of gynecologic cytopathology.


METHODS
Data were collected through a written survey consisting of 98 questions submitted to 1245 Clinical Laboratory Improvement Amendments-licensed or Department of Defense laboratories. There were 541 usable responses. Additional input was sought through a Web posting of results and questions on the College of American Pathologists Web site. Four senior authors who authored the survey and 28 cytopathologists and cytotechnologists were assigned to 5 working groups to analyze data and present statements on good laboratory practices in gynecologic cytopathology at the College of American Pathologists Gynecologic Cytopathology Quality Consensus Conference. Ninety-eight attendees at the College of American Pathologists Gynecologic Cytopathology Quality Consensus Conference discussed and voted on good laboratory practice statements to obtain consensus.


CONCLUSIONS
This paper describes the rationale, background, process, and strengths and limitations of a series of papers that summarize good laboratory practice statements in quality assurance in gynecologic cytopathology.
Department of Pathology, St Joseph Mercy Hospital, Ann Arbor, Michigan 48106, USA. joetworek@yahoo.com
Joseph A
JA
Tworek
Michael R
MR
Henry
Barbara
B
Blond
Bruce Allen
BA
Jones
D003585:Cell Biology / Q000592:standards*; D005260:Female; D005831:Genital Diseases, Female / Q000175:diagnosis; D006176:Gynecology / Q000592:standards*; D006801:Humans; D007753:Laboratories / Q000592:standards*; D030361:Papillomavirus Infections / Q000175:diagnosis; D011785:Quality Assurance, Health Care; D012955:Societies, Medical; D014481:United States