Spatial analysis of health effects of large industrial incinerators in England, 1998-2008: a study using matched case-control areas.
OBJECTIVE
To assess whether residential proximity to industrial incinerators in England is associated with increased risk of cancer incidence and mortality.


METHODS
Retrospective study using matched case-control areas.


METHODS
Five circular regions of radius 10 km near industrial incinerators in England (case regions) and five matched control regions, 1998-2008.


METHODS
All cases of diseases of interest within the circular areas.


METHODS
Counts of childhood cancer incidence (<15 years); childhood leukaemia incidence (<15 years); leukaemia incidence; liver cancer incidence; lung cancer incidence; non-Hodgkin's lymphoma incidence; all-cause mortality; infant mortality (<1 year) and liver cancer mortality.


RESULTS
The estimated relative risks for case circles versus control circles for the nine outcomes considered  range from 0.94 to 1.14, and show neither elevated risk in case circles compared to control areas nor elevated risk with proximity to incinerators within case circles.


CONCLUSIONS
This study applies statistical methods for analysing spatially referenced health outcome data in regions with a hypothesised exposure relative to matched regions with no such exposure. There is no evidence of elevated risk of cancer incidence or mortality in the vicinity of large industrial incinerators in England.
Faculty of Health and Medicine,  Lancaster University, Lancaster,  UK.
Nicola F
NF
Reeve
Thomas R
TR
Fanshawe
Thomas J
TJ
Keegan
Alex G
AG
Stewart
Peter J
PJ
Diggle