Intraoperative cortical mapping of visuospatial functions in parietal low-grade tumors: changing perspectives of neurophysiological mapping.
OBJECTIVE
The aim of this study was to explore the feasibility of intraoperative visuospatial mapping with the same criteria currently used to define essential language areas.


METHODS
The authors compared surgical procedures in 2 patients with similar tumors (Grade II oligodendroglioma in the right parietal lobe) undergoing awake, image-assisted surgery for lesion removal with intraoperative neurophysiological monitoring. The line bisection task was used in both patients but with different criteria.


RESULTS
In the first case, the authors respected any area, even within the tumor, where significant interference was found (a stimulation-induced error in 2 of 3 applications defined an essential area). In the second case, they removed 1 essential area located in the tumor and recorded an uneventful clinical response soon thereafter. They continued to monitor the patient without stimulation and stopped the resection when the patient was close to the criteria valid for defining spatial neglect. The signs of spatial neglect were present for 3 days postoperatively and then cleared spontaneously. Subtotal tumor removal was achieved in both cases.


CONCLUSIONS
Evidence in the present study reveals that areas for visuospatial functions cannot be assessed with the same criteria used for language functions, since essential areas located in the tumor can be safely removed.
Sections of Neurosurgery, Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, Verona, Italy. andrea.talacchi@univr.it
Andrea
A
Talacchi
Giovanna Maddalena
GM
Squintani
Barbara
B
Emanuele
Vincenzo
V
Tramontano
Barbara
B
Santini
Silvia
S
Savazzi
D000328:Adult; D001931:Brain Mapping; D001932:Brain Neoplasms / Q000473:pathology / Q000601:surgery*; D004558:Electric Stimulation / Q000379:methods; D005260:Female; D005910:Glioma / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods; D060787:Neoplasm Grading; D064926:Neurophysiological Monitoring; D019635:Neurosurgical Procedures / Q000379:methods; D016896:Treatment Outcome