[Carotid angioplasty in stenosis following radiotherapy: a review of 12 cases].
BACKGROUND
Carotid stenosis is a complication of cervical radiotherapy. In these cases carotid angioplasty has been considered as the elective revascularisation treatment. Yet, the indication to treat is under discussion due to the high rate of restenosis and the scarcity of studies conducted on the long-term development.


OBJECTIVE
To report on a series of patients with carotid stenosis following radiotherapy who were treated by means of angioplasty, the aim being to analyse their long- and short-term development.


METHODS
Of a series of 426 patients with carotid stenosis treated by endovascular means, 12 of them (2.8%) had previously received radiotherapy in the neck. All of them were submitted to a clinical and imaging follow-up. Data were collected concerning the rate of complications during the first four weeks and in the long term, as well as the rate of restenosis in the follow-up.


RESULTS
The mean interval between radiotherapy and the detection of stenosis was 14.7 years. Ten patients (83.3%) were symptomatic. No complications occurred during the first four weeks following the angioplasty. The mean follow-up time was 45.09 months: 16.7% of patients presented a stroke, 8.3% suffered acute myocardial infarction and 33.3% died (16.6% due to cancer). At least six patients (50%) were diagnosed with restenosis, all equal to or greater than 50% and none of them were symptomatic.


CONCLUSIONS
Carotid angioplasty is a safe, effective technique in stenosis following radiotherapy, with few short-term complications. The rate of carotid restenosis is high. The main cause of death is cancer.
Servicio de Neurología, Hospital Universitari i Politècnic La Fe, Valencia, España. algawmarina@hotmail.com
M
M
Frasquet-Carrera
J I
JI
Tembl
V
V
Parkhutik
D
D
Gorriz-Romero
C
C
Aguilella-Linares
M J
MJ
Ibanez-Julia
A
A
Lago
D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty; D002545:Brain Ischemia / Q000209:etiology; D002277:Carcinoma / Q000532:radiotherapy; D020212:Carotid Artery Injuries / Q000209:etiology*; D016893:Carotid Stenosis / Q000209:etiology / Q000601:surgery*; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011832:Radiation Injuries / Q000209:etiology / Q000601:surgery*; D011878:Radiotherapy / Q000009:adverse effects*; D012008:Recurrence; D015607:Stents