Pyrrolo-isoxazole: a key molecule with diverse biological actions.
Several scientists have synthesized molecules with pyrrolo- isoxazole nucleus and evaluated the molecules for different biological activities. The present review discusses these different compounds with pyrrolo-isoxazole containing nucleus for their neuroprotective, anti-stress, acetylcholinesterase and anti-amnestic, antihypertensive and antibacterial activities.
Preet
P
Anand
Department of Chemistry, Punjabi University, Patiala-147002, Punjab, India. baldev.chemistry@gmail.com.
Baldev
B
Singh
D000110:Acetylcholinesterase / Q000378:metabolism; D000647:Amnesia / Q000188:drug therapy; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects; D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007555:Isoxazoles / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use*; D015394:Molecular Structure; D018696:Neuroprotective Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D011758:Pyrroles / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use*; D013315:Stress, Psychological / Q000188:drug therapy; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D002800:Cholinesterase Inhibitors; D007555:Isoxazoles; D018696:Neuroprotective Agents; D011758:Pyrroles; D000110:Acetylcholinesterase