Dietary vitamin D intake and muscle mass in older women. Results from a cross-sectional analysis of the EPIDOS study.
OBJECTIVE
Vitamin D intake may prevent physical performance decline through prevention of muscle mass loss. Our objective was to determine whether low dietary intakes were associated with low muscle mass (MM).


METHODS
Cross-sectional analysis of 1989 community-dwelling women (mean age 80.5±3.8years) from the EPIDémiologie de l'OStéoporose (EPIDOS) study were assessed at baseline.


METHODS
Low intakes of vitamin D (<70µg/week) were estimated from the weekly dietary vitamin D intakes (self-administered food frequency questionnaire). Low MM was defined according to the appendicular skeletal muscle mass index assessed using Dual Energy X-ray Absorptiometry, divided by square height of less than 5.45 kg/m2. Usual gait speed defined physical performance. Age, sun exposure, co-morbidities, education level, living arrangements, recreational physical activity, dietary protein and calcium intakes, bone mineral density, handgrip strength, and body mass index were considered as potential confounders. Multivariate logistic regression analyses assessed the association between low vitamin D intakes and low MM.


RESULTS
Two-hundred and nine (10.5%) women with low MM were compared to 1,780 women with normal MM. In final model, obesity/overweight (Adjusted Odds Ratios, aOR=0.09; 95%CI [0.05-0.17]), malnutrition (aOR=3.90; 95%CI [2.74-5.54]) and low handgrip strength (aOR=2.33; 95%CI [1.44-3.77]; p<0.001) were statistically associated with a low MM status.


CONCLUSIONS
No association with low MM has been reported regarding low dietary intakes of vitamin D.
Gérontopôle, Department of Internal Medicine and Geriatrics, Toulouse University Hospital, Toulouse, France. dupuy.c@chu-toulouse.fr
C
C
Dupuy
V
V
Lauwers-Cances
G Abellan
GA
van Kan
S
S
Gillette
A-M
AM
Schott
O
O
Beauchet
C
C
Annweiler
B
B
Vellas
Y
Y
Rolland
D015502:Absorptiometry, Photon; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D004032:Diet; D002149:Energy Intake; D005260:Female; D005684:Gait; D018737:Hand Strength; D006801:Humans; D016015:Logistic Models; D044342:Malnutrition / Q000150:complications; D015999:Multivariate Analysis; D018482:Muscle, Skeletal / Q000473:pathology* / Q000503:physiopathology; D015596:Nutrition Assessment; D009765:Obesity / Q000150:complications; D016017:Odds Ratio; D009929:Organ Size; D010809:Physical Fitness; D055948:Sarcopenia / Q000209:etiology* / Q000503:physiopathology; D011795:Surveys and Questionnaires; D014807:Vitamin D / Q000008:administration & dosage*; D014808:Vitamin D Deficiency / Q000150:complications
D014807:Vitamin D