Direct access to acylated azobenzenes via Pd-catalyzed C-H functionalization and further transformation into an indazole backbone.
Azobenzenes were readily acylated at the 2-position through a Pd-catalyzed C-H functionalization from simple aromatic azo compounds and aldehydes in good yields. The obtained acylated azobenzenes could be efficiently converted into the corresponding indazole derivatives in nearly quantitative yields.
Department of Chemistry, Huaibei Normal University, Huaibei, Anhui 235000, PR China.
Hongji
H
Li
Pinhua
P
Li
Lei
L
Wang