Global NeuroAIDS roundtable.
In May 2012, the Division of AIDS Research at the National Institute of Mental Health (NIMH) organized the "Global NeuroAIDS Roundtable" in conjunction with the 11th International Symposium on Neurovirology and the 2012 Conference on HIV in the Nervous System. The meeting was held in New York, NY, USA and brought together NIMH-funded investigators who are currently working on projects related to the neurological complications of AIDS (NeuroAIDS) in Africa, Asia, Eastern Europe, and Latin America in order to provide an opportunity to share their recent findings and discuss the challenges encountered within each country. The major goals of the roundtable were to evaluate HIV-associated neurocognitive impairment and determine if it may be directly attributable to distinct HIV subtypes or clades and to discuss the future priorities for global NeuroAIDS research. At the "Global NeuroAIDS Roundtable", presentations of preliminary research indicated that HIV-associated neurocognitive impairment is prevalent in all countries examined regardless of which HIV clade is present in the region. The only clear-cut difference between HIV-1 clades was in relation to subtypes A and D in Uganda. However, a key point that emerged from the discussions was that there is an urgent need to standardize neurocognitive assessment methodologies across the globe before definitive conclusions can be drawn regarding the relationship between HIV clade diversity and neuropathogenesis. Future research directions were also discussed at the roundtable with particular emphasis on the potential of viral and host factor molecular interactions to impact the pathophysiology of HIV-associated neurocognitive disorders (HAND) from a global perspective.
Division of AIDS Research, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA, jjeymoha@mail.nih.gov
Jeymohan
J
Joseph
Cristian L
CL
Achim
Michael J
MJ
Boivin
Bruce J
BJ
Brew
David B
DB
Clifford
Deborah A
DA
Colosi
Ronald J
RJ
Ellis
Robert K
RK
Heaton
Amadou
A
Gallo-Diop
Igor
I
Grant
Georgette D
GD
Kanmogne
Mahendra
M
Kumar
Scott
S
Letendre
Thomas D
TD
Marcotte
Avindra
A
Nath
Carlos A
CA
Pardo
Robert H
RH
Paul
Lynn
L
Pulliam
Kevin
K
Robertson
Walter
W
Royal
Ned
N
Sacktor
Pasiri
P
Sithinamsuwan
Davey M
DM
Smith
Victor
V
Valcour
Brian
B
Wigdahl
Charles
C
Wood
D015526:AIDS Dementia Complex / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology; D014943:Global Health / Q000592:standards*; D006301:Health Services Needs and Demand; D006801:Humans; D009483:Neuropsychological Tests / Q000592:standards