Acid suppression does not reduce symptoms from vocal cord dysfunction, where gastro-laryngeal reflux is a known trigger.
Vocal cord dysfunction (VCD) is characterized by paradoxical inspiratory abduction of the vocal cords. Gastro-oesophageal reflux disease (GORD) is a known trigger. We studied 77 patients referred to a tertiary VCD clinic. VCD was diagnosed in 62, of which 83.9% had proven GORD. Following 8 weeks of acid suppression, 24.2% reported improvement in the severity and frequency of VCD attacks. This study suggests that empirical treatment of GORD in VCD marginally improves symptom control.
Kerry
K
Woolnough
John
J
Blakey
Nicola
N
Pargeter
Adel
A
Mansur
D050782:Esophageal pH Monitoring; D005744:Gastric Acid / Q000378:metabolism*; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000378:metabolism; D006801:Humans; D007827:Laryngitis / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism; D008875:Middle Aged; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*; D012720:Severity of Illness Index; D014827:Vocal Cords / Q000503:physiopathology*
D054328:Proton Pump Inhibitors