An efficient microwave-assisted Suzuki reaction using a new pyridine-pyrazole/Pd(II) species as catalyst in aqueous media.
A new pyridine-pyrazole N-N ligand has been conveniently synthesized and characterized by ¹H-, ¹³C-NMR, IR spectroscopies, HRMS and X-ray single-crystal crystallography analyses. The ligand adds to palladium(II) under basic conditions to give high yields of an air-stable and water-soluble complex that was fully characterized by NMR and HRMS. The complex was investigated as a catalyst for the Suzuki reaction in aqueous media under microwave irradiation. The compound proved to be an effective catalyst.
Key Laboratory of Development and Application of Forest Chemicals of Guangxi, College of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Nanning 530006, China. liqunshen@126.com
Liqun
L
Shen
Suyu
S
Huang
Yuanmei
Y
Nie
Fuhou
F
Lei
D001897:Boronic Acids / Q000737:chemistry; D002384:Catalysis; D002625:Chemistry, Organic / Q000379:methods*; D018360:Crystallography, X-Ray; D008024:Ligands; D008872:Microwaves; D008968:Molecular Conformation; D010165:Palladium / Q000737:chemistry*; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry*; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry*; D059027:Recycling; D012997:Solvents / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D014867:Water / Q000737:chemistry*
D001897:Boronic Acids; D008024:Ligands; D011720:Pyrazoles; D011725:Pyridines; D012997:Solvents; D014867:Water; C031280:pyrazole; D010165:Palladium; C023666:pyridine