Mesh-based approach for the 3D analysis of anatomical structures of interest in radiotherapy.
In this paper a method based on mesh surfaces approximations for the 3D analysis of anatomical structures in Radiotherapy (RT) is presented. Parotid glands meshes constructed from Megavoltage CT (MVCT) images were studied in terms of volume, distance between center of mass (distCOM) of the right and left parotids, dice similarity coefficient (DICE), maximum distance between meshes (DMax) and the average symmetric distance (ASD). A comparison with the standard binary images approach was performed. While absence of significant differences in terms of volume, DistCOM and DICE indices suggests that both approaches are comparable, the fact that the ASD showed significant difference (p=0.002) and the DMax was almost significant (p=0.053) suggests that the mesh approach should be adopted to provide accurate comparison between 3D anatomical structures of interest in RT.
Institute of Molecular Bioimaging and Physiology, IBFM-CNR, Milan, Italy and Bioengineering Department, Politecnico di Milano, Milan, Italy. armero83@gmail.com
Aldo R
AR
Mejia-Rodriguez
Elisa
E
Scalco
Daniele
D
Tresoldi
Anna M
AM
Bianchi
Edgar R
ER
Arce-Santana
Martin O
MO
Mendez
Giovanna
G
Rizzo
D000465:Algorithms; D003198:Computer Simulation; D001330:Electronic Data Processing; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008953:Models, Anatomic; D015233:Models, Statistical; D015588:Observer Variation; D010306:Parotid Gland / Q000000981:diagnostic imaging* / Q000473:pathology; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods; D011878:Radiotherapy / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D012815:Signal Processing, Computer-Assisted; D014057:Tomography, X-Ray Computed / Q000379:methods