Stimulus-sensitive myoclonus and cerebellar ataxia following chikungunya meningoencephalitis.
Chikungunya virus was initially thought to be a non-neurotropic virus, but recently neurological complications have been reported in patients with chikungunya virus infection. Here, we report a rare case of stimulus-sensitive myoclonus following chikungunya meningoencephalitis. The cranial MRI scan of the patient was normal, the cerebrospinal fluid contained 200 lymphocytes/mm(3), and the serum immunoglobulin M ELISA was positive for chikungunya. The patient improved completely after 1 month of treatment. This case study illustrates that chikungunya virus should also be considered in a febrile patient with myoclonus, especially in an endemic area.
Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareily Road, Lucknow, 226014, India. jayanteek@yahoo.com
J
J
Kalita
P
P
Kumar
U K
UK
Misra
D000328:Adult; D018354:Alphavirus Infections / Q000150:complications*; D000914:Antibodies, Viral / Q000097:blood*; D002524:Cerebellar Ataxia / Q000150:complications / Q000175:diagnosis / Q000209:etiology*; D002555:Cerebrospinal Fluid / Q000166:cytology; D065632:Chikungunya Fever; D002646:Chikungunya virus / Q000276:immunology* / Q000302:isolation & purification; D004797:Enzyme-Linked Immunosorbent Assay; D006257:Head / Q000000981:diagnostic imaging; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008279:Magnetic Resonance Imaging; D008297:Male; D008590:Meningoencephalitis / Q000150:complications*; D009207:Myoclonus / Q000150:complications / Q000175:diagnosis / Q000209:etiology*; D011859:Radiography
D000914:Antibodies, Viral; D007074:Immunoglobulin G