t(17;19) in Children with Acute Lymphocytic Leukemia: A Report of 3 Cases and a Review of the Literature.
Several cytogenetic abnormalities identified in patients with childhood acute lymphocytic leukemia (ALL) have been associated with a poor prognosis. There are several case reports in the literature describing t(17;19) in children with ALL. This translocation has been associated with hypercalcemia, coagulopathy, and poor outcome. We present three cases of ALL with t(17;19) treated at our institution and review the outcome of children reported in the medical literature.
Department of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN 37232, USA.
Katherine A
KA
Minson
Pinki
P
Prasad
Susan
S
Vear
Scott
S
Borinstein
Richard
R
Ho
Jennifer
J
Domm
Haydar
H
Frangoul