HTQC: a fast quality control toolkit for Illumina sequencing data.
BACKGROUND
Illumina sequencing platform is widely used in genome research. Sequence reads quality assessment and control are needed for downstream analysis. However, software that provides efficient quality assessment and versatile filtration methods is still lacking.


RESULTS
We have developed a toolkit named HTQC - abbreviation of High-Throughput Quality Control - for sequence reads quality control, which consists of six programs for reads quality assessment, reads filtration and generation of graphic reports.


CONCLUSIONS
The HTQC toolkit can generate reads quality assessment faster than existing tools, providing guidance for reads filtration utilities that allow users to choose different strategies to remove low quality reads.
CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, NO,1 West Beichen Road, Chaoyang District, Beijing, China.
Xi
X
Yang
Di
D
Liu
Fei
F
Liu
Jun
J
Wu
Jing
J
Zou
Xue
X
Xiao
Fangqing
F
Zhao
Baoli
B
Zhu
D023281:Genomics; D006801:Humans; D011786:Quality Control; D017422:Sequence Analysis, DNA / Q000592:standards*; D012984:Software