Chondrosarcoma in childhood: the radiologic and clinical conundrum.
Less than 10% of chondrosarcomas occur in children. In addition, as little as 0.5% of low-grade chondrosarcomas arise secondarily from benign chondroid lesions. The presence of focal pain is often used to crudely distinguish a chondrosarcoma (which is usually managed with wide surgical excision), from a benign chondroid lesion (which can be followed by clinical exams and imaging surveillance). Given the difficulty of localizing pain in the pediatric population, initial radiology findings and short-interval follow-up, both imaging and clinical, are critical to accurately differentiate a chondrosarcoma from a benign chondroid lesion. To our knowledge, no case in the literature discusses a chondrosarcoma possibly arising secondarily from an enchondroma in a pediatric patient. We present a clinicopathologic and radiology review of conventional chondrosarcomas. We also attempt to further the understanding of how to manage a chondroid lesion in the pediatric patient with only vague or bilateral complaints of pain.
Department of Pediatrics, Ireland Army Community Hospital, Fort Knox, KY, USA.
Susan M
SM
Mosier
Tanvi
T
Patel
Karen
K
Strenge
Andrew D
AD
Mosier
D001845:Bone Cysts / Q000175:diagnosis; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D002648:Child; D002812:Chondroma / Q000175:diagnosis; D002813:Chondrosarcoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003287:Contrast Media; D003937:Diagnosis, Differential; D005269:Femur / Q000000981:diagnostic imaging* / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D011859:Radiography; D013997:Time Factors; D016896:Treatment Outcome
D003287:Contrast Media
bone tumor; chondrosarcoma; pediatric; pediatric chondrosarcoma