Severe bacterial superinfection based on influenza A (H1N1) pneumonia in a heart-lung transplant recipient.
A 47-year-old heart-lung transplant recipient presented to our outpatient transplant clinic with respiratory infection. Her nose and throat swabs for influenza A (H1N1) infection were negative. Broncheoalveolar lavage showed a positive result for H1N1 infection. Antiviral therapy was initiated. Because of superinfection with Pseudomonas aeruginosa and Aspergillus terreus, her clinical condition worsened. The clinical condition of the patient improved with antibiotic and antifungal treatment. Negative nose and throat swab results cannot rule out H1N1 infection safely. We therefore advocate to routinely perform broncheoalveolar lavage.
Department of Cardiovascular Surgery, University Heart Center, Hamburg, Germany. y.yildirim@uke.de
Y
Y
Yildirim
S
S
Pecha
B
B
Sill
T
T
Deuse
H
H
Reichenspurner
D001228:Aspergillosis / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology; D001230:Aspergillus / Q000302:isolation & purification; D018893:Bronchoalveolar Lavage / Q000379:methods; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology / Q000821:virology; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D016041:Heart-Lung Transplantation; D006801:Humans; D006976:Hypertension, Pulmonary / Q000601:surgery; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000150:complications / Q000175:diagnosis* / Q000821:virology; D008875:Middle Aged; D011552:Pseudomonas Infections / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D013902:Radiography, Thoracic; D020545:Respiratory Mucosa / Q000382:microbiology / Q000821:virology; D012720:Severity of Illness Index; D015163:Superinfection / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed