Chemotherapy and radiation therapy in 4 dogs with muscle-invasive transitional cell carcinoma of the urinary tract.
Four dogs with T(2)N(0)M(0) transitional cell carcinoma of the lower urinary tract underwent multimodal treatment consisting of neoadjuvant chemotherapy, external-beam radiotherapy, and adjuvant chemotherapy. No significant toxicity was documented. All dogs showed clinical improvement and reduction of tumor volume based on computed tomography (CT).
Animal Oncology and Imaging Center, Hünenberg, Switzerland. lauramarconato@yahoo.it
Laura
L
Marconato
Dagmar B
DB
Nitzl
Katja J
KJ
Melzer-Ruess
Marcel A
MA
Keller
Julia
J
Buchholz
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002295:Carcinoma, Transitional Cell / Q000628:therapy / Q000662:veterinary*; D017024:Chemotherapy, Adjuvant / Q000662:veterinary; D004283:Dog Diseases / Q000628:therapy*; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D019042:Muscle Neoplasms / Q000628:therapy / Q000662:veterinary*; D009361:Neoplasm Invasiveness; D011878:Radiotherapy / Q000662:veterinary; D016896:Treatment Outcome; D014571:Urologic Neoplasms / Q000628:therapy / Q000662:veterinary*
D000970:Antineoplastic Agents