Multisystemic Langerhans cell histiocytosis with advanced lung involvement.
Langerhans cell histiocytosis is a rare disease of unknown cause, characterized by the proliferation of histiocytic cells (Langerhans cells), that can sometimes be especially difficult to diagnose due to its wide clinical spectrum, ranging from a single lesion to a multisystemic disorder. Appropriate disease staging is fundamental, since treatment depends upon the severity of the disease, and imaging methods play a fundamental role not only in diagnosing and assessing the extent of Langerhans cell histiocytosis, as well as guiding the appropriate treatment for the patient and their monitoring.
Department of Radiology, UFES, Vitória, Brazil. ricardoafmello@gmail.com
Ricardo Andrade Fernandes
RA
de Mello
Joana Waked
JW
Tanos
Melissa Bozzi Nonato
MB
Mello
Edson
E
Marchiori
D006646:Histiocytosis, Langerhans-Cell / Q000000981:diagnostic imaging*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
Langerhans cell histiocytosis; computed tomography; lung; skin diseases