[Plasmodium knowlesi: an emerging species in humans?].
Plasmodium knowlesi is typically found in macaques and has recently been recognized as the fifth Plasmodium species to cause malaria in humans. Several cases of P. knowlesi malaria have been reported in people in Southeast Asia. Most cases are simple but approximately one in 10 patients develops complications. The morphology of P. knowlesi parasites in human infections closely resembles that of Plasmodium malariae or Plasmodium falciparum, so a molecular method is the optimum diagnostic procedure. The treatment of choice for uncomplicated P. knowlesi malaria is oral chloroquine, whereas severe infection should be treated with intravenous quinine.
Hôpital d'instruction des armées Bégin, laboratoire de biologie, 69, avenue de Paris, 94163 Saint-Mandé cedex, France. a_servonnet@yahoo.fr
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D006801:Humans; D008288:Malaria / Q000175:diagnosis / Q000188:drug therapy; D016790:Plasmodium knowlesi
Plasmodium knowlesi; Southeast Asia; malaria