Suppression tuning of distortion-product otoacoustic emissions: results from cochlear mechanics simulation.
This paper presents the results of simulating the acoustic suppression of distortion-product otoacoustic emissions (DPOAEs) from a computer model of cochlear mechanics. A tone suppressor was introduced, causing the DPOAE level to decrease, and the decrement was plotted against an increasing suppressor level. Suppression threshold was estimated from the resulting suppression growth functions (SGFs), and suppression tuning curves (STCs) were obtained by plotting the suppression threshold as a function of suppressor frequency. Results show that the slope of SGFs is generally higher for low-frequency suppressors than high-frequency suppressors, resembling those obtained from normal hearing human ears. By comparing responses of normal (100%) vs reduced (50%) outer-hair-cell sensitivities, the model predicts that the tip-to-tail difference of the STCs correlates well with that of intra-cochlear iso-displacement tuning curves. The correlation is poorer, however, between the sharpness of the STCs and that of the intra-cochlear tuning curves. These results agree qualitatively with what was recently reported from normal-hearing and hearing-impaired human subjects, and examination of intra-cochlear model responses can provide the needed insight regarding the interpretation of DPOAE STCs obtained in individual ears.
Department of Electrical Engineering, National Tsing Hua University, Hsinchu 30013, Taiwan. ywliu@ee.nthu.edu.tw
Yi-Wen
YW
Liu
Stephen T
ST
Neely
D000161:Acoustic Stimulation; D001309:Auditory Threshold; D001696:Biomechanical Phenomena; D003051:Cochlea / Q000502:physiology*; D003198:Computer Simulation; D018072:Hair Cells, Auditory, Outer / Q000502:physiology; D006311:Hearing Disorders / Q000503:physiopathology; D006801:Humans; D016014:Linear Models; D040542:Mechanotransduction, Cellular; D008954:Models, Biological; D009038:Motion; D017711:Nonlinear Dynamics; D017084:Otoacoustic Emissions, Spontaneous; D011312:Pressure; D013016:Sound; D013997:Time Factors