Background data for hematological and blood chemical examinations in juvenile beagles.
As the first step to get historical background data for physiological examinations in juvenile dogs, hematology and blood chemistry data obtained from juvenile beagle dogs (less than 3 months of age) used in the control group of toxicity studies conducted in our laboratory were summarized and compared with those obtained from adult beagle dogs (6 months of age). In the hematological examination, growth of beagle dogs was shown to be associated with increases in erythrocyte parameters and with decreases in reticulocyte and leukocyte counts. In the blood chemical examination, growth of beagle dogs was shown to be associated with increases in aspartate aminotransferase, alanine aminotransferase, and creatinine and with decreases in creatine phosphokinase, glucose, total cholesterol, and calcium. The differential leukocyte ratio showed no age relation, but the actual count showed a tendency toward decrease. Alkaline phosphatase showed a tendency to increase from 0 months of age to 3 months of age, but it decreased at 6 months of age. The present results were roughly similar to those previously reported.
Kannami Laboratory, Bozo Research Center Inc., 1308-125 Kuwahara-Sanbonmatsu, Kannami-cho, Tagata-gun, Shizuoka 419-0101, Japan.
Toshiya
T
Ishii
Hisako
H
Hori
Makoto
M
Ishigami
Hiroyasu
H
Mizuguchi
Dai
D
Watanabe
D000375:Aging; D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001772:Blood Cell Count; D001774:Blood Chemical Analysis; D001786:Blood Glucose; D002118:Calcium / Q000097:blood; D002784:Cholesterol / Q000097:blood; D003402:Creatine Kinase / Q000097:blood; D003404:Creatinine / Q000097:blood; D004285:Dogs / Q000254:growth & development*; D005260:Female; D006403:Hematologic Tests; D008297:Male; D018675:Toxicity Tests
D001786:Blood Glucose; D002784:Cholesterol; D003404:Creatinine; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D003402:Creatine Kinase; D002118:Calcium