Phosphine-catalyzed [3+2] annulation of α-substituted allenoates with ester-activated α,β-unsaturated imines: a novel variation of the Lu [3+2] cycloaddition reaction.
A phosphine-catalyzed [3+2] annulation reaction of α-substituted allenoates with ester-activated α,β-unsaturated imines is reported, which provides new and efficient access to highly functionalized cyclopentenes bearing one all-carbon quaternary center. This reaction also expands the scope of the famous Lu [3+2] cycloaddition reaction.
The State Key Laboratory of Elemento-Organic Chemistry and Department of Chemistry, Nankai University, 94 Weijin Road, Tianjin, 300071, China.
Junjun
J
Tian
Zhengjie
Z
He