Lymphotoxin β receptor mediates caspase-dependent tumor cell apoptosis in vitro and tumor suppression in vivo despite induction of NF-κB activation.
Department of Biochemistry and Molecular Biology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA.
Xiaolin
X
Hu
Mary A
MA
Zimmerman
Kankana
K
Bardhan
Dafeng
D
Yang
Jennifer L
JL
Waller
Georgia B
GB
Liles
Jeffrey R
JR
Lee
Raphael
R
Pollock
Dina
D
Lev
Carl F
CF
Ware
Ellen
E
Garber
Veronique
V
Bailly
Jeffrey L
JL
Browning
Kebin
K
Liu
D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D020169:Caspases / Q000235:genetics / Q000378:metabolism*; D045744:Cell Line, Tumor; D003110:Colonic Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D006801:Humans; D008024:Ligands; D053259:Lymphotoxin beta Receptor / Q000235:genetics / Q000378:metabolism*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D008928:Mitochondria / Q000235:genetics / Q000378:metabolism; D016328:NF-kappa B / Q000235:genetics / Q000378:metabolism*; D014183:Transplantation, Heterologous; D025521:Tumor Suppressor Proteins / Q000235:genetics / Q000378:metabolism*
D008024:Ligands; D053259:Lymphotoxin beta Receptor; D016328:NF-kappa B; D025521:Tumor Suppressor Proteins; D020169:Caspases