Graphene oxide-based fluorescent biosensor for protein detection via terminal protection of small-molecule-linked DNA.
A fluorescence method for protein detection is developed based on terminal protection of small-molecule-linked DNA by target protein and a graphene oxide-assisted DNA assay strategy. This design results in fluorescence-enhanced detection that is sensitive and selective for the target protein.
College of Chemistry and Molecular Sciences, Research Center for Nanobiology and Nanomedicine-MOE 985 Innovative Platform, Wuhan Institute of Biotechnology, and State Key Laboratory of Virology, Wuhan University, Wuhan 430072, PR China.
Yue
Y
He
Xiaojing
X
Xing
Hongwu
H
Tang
Daiwen
D
Pang
D015374:Biosensing Techniques / Q000379:methods*; D004247:DNA / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D011506:Proteins / Q000032:analysis* / Q000737:chemistry; D013050:Spectrometry, Fluorescence
D011506:Proteins; D006108:Graphite; D004247:DNA