Hypoadrenal syndrome in a patient with amyloidosis secondary to familial Mediterranean fever.
Amyloidosis is a common complication of poorly controlled familial Mediterranean fever (FMF). A variety of organs including kidneys, heart, liver, thyroid and adrenal glands may be clinically affected. However, involvement of adrenal glands leading to significant inefficiency is rarely seen in FMF patients with amyloidosis. The impairment of neuroendocrine immune system in FMF together with proteinuria in renal amyloidosis is a challenge while interpreting adrenal function tests. Here we present a case report of a 42-year-old man with FMF and renal failure due to amyloidosis whose disease course was complicated by adrenal insufficiency.
Department of Pulmonary Medicine, Tehran University of Medical Sciences, Iran. asadi_m@tums.ac.ir
Mehrnaz Asadi
MA
Gharabaghi
Aram
A
Behdadnia
Mehrnoush Asadi
MA
Gharabaghi
Hamidreza
H
Abtahi
D000309:Adrenal Insufficiency / Q000188:drug therapy / Q000209:etiology*; D000328:Adult; D000686:Amyloidosis / Q000150:complications / Q000209:etiology*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003967:Diarrhea / Q000209:etiology; D010505:Familial Mediterranean Fever / Q000150:complications*; D017809:Fatal Outcome; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007022:Hypotension / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000209:etiology* / Q000628:therapy; D008297:Male; D013974:Thyroxine / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D013974:Thyroxine; D006854:Hydrocortisone