[Role of hormonal disturbances in sterility development for patients with benign formations of ovaries].
The article presents hormonal analysis of hypothalamus-hypophysis-ovaries system of 14 patients with sterility as well as of other 15 patients without sterility suffering from benign tumors or tumorous formations. The control group included 6 healthy women. The concentration of hormones in blood serum (FSH-follicle stimulating hormone, LH-lutein hormone, Prolactinum, Testosteronum, Oestradiolum, Progesterone) has been tested in dynamics of a menstrual cycle. Correlation of results of hormonal and histological analysis of a capsule of formation and a biopsy of a tissue of an ovary of these patients has revealed that formation occurrence irrespective of its histological type leads to suppression of the follicular apparatus. These disturbances are more symptomatic for patients with both epithelial cystomas and sterility. It gives evidence that these disturbances can cause sterility. Hormonal disturbances of patients with benign tumors or tumorous formations depend on formation presence, rather than of its histological type. Spontaneous recovery of reproductive function is marked at 35 % of patients. Efficiency of surgery treatment and rehabilitation therapy within the first year after surgery made up 60 %.
L M
LM
Abdullaeva
G S
GS
Babadzhanova
D B
DB
Nazarova
N D
ND
Muratova
U A
UA
Ashurova
D000328:Adult; D001706:Biopsy; D016022:Case-Control Studies; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000378:metabolism* / Q000503:physiopathology; D007247:Infertility, Female / Q000097:blood* / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D007986:Luteinizing Hormone / Q000097:blood; D008597:Menstrual Cycle / Q000502:physiology; D009369:Neoplasms / Q000097:blood* / Q000150:complications / Q000503:physiopathology / Q000601:surgery; D010051:Ovarian Neoplasms / Q000097:blood* / Q000150:complications / Q000503:physiopathology / Q000601:surgery; D010053:Ovary / Q000378:metabolism* / Q000503:physiopathology; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D012098:Reproduction; D013739:Testosterone / Q000097:blood
D013739:Testosterone; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone