[Serum A1-antitrypsin levels in prostate pathology].
The serum alpha1-antitrypsin (AAT) levels were determined using enzyme-linked immunosorbent assay (ELISA) and turbidimetry in patients with prostate cancer, patients with benign prostatic hyperplasia and healthy volunteers. Both methods revealed a significant increase of serum AAT levels in patients with prostate cancer compared with patients with BPH and healthy men. ELISA, as used in study, was more sensitive to changes in the concentration of AAT, but the sensitivity of the turbidimetry allows to use this method in the early diagnosis of prostate cancer.
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Dokrunova
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Sokolova
D000368:Aged; D000369:Aged, 80 and over; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood*; D012680:Sensitivity and Specificity; D000515:alpha 1-Antitrypsin / Q000097:blood*
D000515:alpha 1-Antitrypsin