[Assessment of an association between fatty acid structure of lipids in pulmonary surfactant and 137Cs content in the body of children, residents of radiation-contaminated areas].
An evaluation of correlation between fatty acid composition in pulmonary surfactant lipids and 137Cs content in the body of children, residents of radiation-contaminated areas revealed that a increased incorporation of 137Cs promotes a disruption of fatty acid balance towards an increase in the saturation of the surfactant lipid complex, a destruction of lecithin fraction of surfactant, a decrease in antioxidant properties of surfactant system, an activation of lipid peroxidation processes in the respiratory area of lung by lipoxygenase type, a disturbance of polyunsaturated fatty acid metabolism on the stage of bioregulators-eicosanoid formation.
V M
VM
Parkhomenko
I Ie
IIe
Kolpakov
O M
OM
Studenykina
T S
TS
Briuzhina
H P
HP
Artemchuk
D002588:Cesium Radioisotopes / Q000032:analysis*; D047852:Chernobyl Nuclear Accident; D002648:Child; D015777:Eicosanoids / Q000032:analysis; D060733:Electromagnetic Radiation; D045853:Exhalation; D005227:Fatty Acids / Q000032:analysis* / Q000737:chemistry; D005231:Fatty Acids, Unsaturated / Q000032:analysis* / Q000737:chemistry; D006801:Humans; D054709:Lecithins / Q000032:analysis; D050356:Lipid Metabolism / Q000528:radiation effects*; D015227:Lipid Peroxidation / Q000528:radiation effects; D058945:Lipoxygenases / Q000378:metabolism; D008168:Lung / Q000378:metabolism / Q000528:radiation effects*; D011663:Pulmonary Surfactants / Q000737:chemistry / Q000528:radiation effects*; D011829:Radiation Dosage; D011874:Radiometry; D014455:Ukraine
D002588:Cesium Radioisotopes; D015777:Eicosanoids; D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D054709:Lecithins; D011663:Pulmonary Surfactants; D058945:Lipoxygenases