Energy landscape and dynamics of biomolecules extended abstract.
Proteins are not isolated homogeneous systems. Each protein can exist in a very large number of conformations (conformational substates) that are characterized by an energy landscape. The main conformational motions, similar to the α and β fluctuations in glasses, are linked to fluctuations in the bulk solvent and the hydration shell.
Theory Division T10, Los Alamos National Laboratory, Los Alamos, NM 87545.
Hans
H
Frauenfelder
alpha and beta relaxations; protein dynamics; protein energy landscape; protein fluctuations; slaving