Pre-implantation electrochemical characterization of a Parylene C sheath microelectrode array probe.
We present the preliminary electrochemical characterization of 3D Parylene C sheath microelectrode array probes towards realizing reliable chronic neuroprosthetic recordings. Electrochemical techniques were used to verify electrode integrity after our novel post-fabrication thermoforming process was applied to flat surface micromachined structures to achieve a hollow sheath probe shape. Characterization of subsequent neurotrophic coatings was performed and accelerated life testing was used to simulate six months in vivo. Prior to probe implantation, crosstalk was measured and electrode surface properties were evaluated through the use of electrochemical impedance spectroscopy.
Department of Biomedical Engineering at the University of Southern California, Los Angeles, CA 90089, USA.
Seth A
SA
Hara
Brian J
BJ
Kim
Jonathan T W
JT
Kuo
Curtis
C
Lee
Christian A
CA
Gutierrez
Tuan
T
Hoang
Ellis
E
Meng
D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D017097:Electric Impedance; D004563:Electrochemistry / Q000379:methods; D004567:Electrodes, Implanted; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008422:Materials Testing; D008839:Microelectrodes; D011108:Polymers / Q000737:chemistry*; D019919:Prosthesis Implantation; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014992:Xylenes / Q000737:chemistry*
D020099:Coated Materials, Biocompatible; D011108:Polymers; D014992:Xylenes; C011055:parylene