Structure elucidation of four prenylindole derivatives from Streptomyces sp. isolated from Ailuropoda melanoleuca feces.
Four new prenylindole derivatives, (R)-6-(2,3-dihydroxy-3-methylbutyl)indole (1), (R)-6-(2,3-dihydroxy-3-methylbutyl)indolin-2-one (2), and an unseparated mixture of (Z)-6-(4-hydroxy-3-methylbut-2-en-1-yl)indolin-2-one (3a) and (E)-6-(4-hydroxy-3-methylbut-2-en-1-yl)indolin-2-one (3b) with a ratio of 3 : 2, were isolated from the culture broth of a streptomycete isolated from Ailuropoda melanoleuca feces. Their structures were elucidated on the basis of 1D and 2D NMR spectroscopic techniques. The absolute configuration of 1 was determined by Mosher's method.
Dan
D
Zheng
Li
L
Han
Yi
Y
Jiang
Yan-Ru
YR
Cao
Jiang
J
Liu
Xiu
X
Chen
Yi-Qing
YQ
Li
Xue-Shi
XS
Huang
D000818:Animals; D005243:Feces / Q000382:microbiology*; D007211:Indoles / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013302:Streptomyces / Q000737:chemistry*; D001503:Ursidae / Q000382:microbiology*
D007211:Indoles