A school-based study with Rome III criteria on the prevalence of functional gastrointestinal disorders in Chinese college and university students.
BACKGROUND
Functional gastrointestinal disorders, including functional dyspepsia, irritable bowel syndrome and functional constipation are very common worldwide.


OBJECTIVE
This research aims to estimate the prevalence and associated factors involved in functional gastrointestinal disorders in Chinese college and university students using the Rome III criteria.


METHODS
A total of 5000 students from Shandong University in China were asked in January-May 2012 to complete questionnaires, including the Rome III questionnaire, hospital anxiety and depression scale, and negative life events scale.


RESULTS
Based on the 4638 students who completed the questionnaire, the prevalence of functional dyspepsia, irritable bowel syndrome and functional constipation in college and university students of North China worked out to be 9.25%, 8.34% and 5.45% respectively. They were more frequent in female students. The factors of anxiety (OR 1.07; 95% CI 0.99 to 1.16, P=0.002<0.05) and depression (OR 0.55; 95% CI 0.15 to 1.05, P=0.045<0.05) indicated a high risk of causing irritable bowel syndrome.


CONCLUSIONS
Functional dyspepsia, irritable bowel syndrome and functional constipation were common in college and university students of North China. Psychological disorders such as anxiety and depression provide significant risk factors for irritable bowel syndrome patients.
Department of Gastroenterology, Qilu Hospital, Shandong University, Jinan, Shandong, People's Republic of China.
Yan-Yan
YY
Dong
Fei-Xue
FX
Chen
Yan-Bo
YB
Yu
Chao
C
Du
Qing-Qing
QQ
Qi
Han
H
Liu
Yan-Qing
YQ
Li
D001007:Anxiety / Q000453:epidemiology; D044466:Asian People / Q000706:statistics & numerical data; D002681:China / Q000453:epidemiology; D015897:Comorbidity; D003248:Constipation / Q000453:epidemiology; D003863:Depression / Q000453:epidemiology; D004415:Dyspepsia / Q000453:epidemiology; D005260:Female; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000453:epidemiology; D016015:Logistic Models; D008297:Male; D015995:Prevalence; D018570:Risk Assessment / Q000706:statistics & numerical data; D012307:Risk Factors; D013334:Students / Q000523:psychology / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires; D014495:Universities; D055815:Young Adult