Skin involvement in primary systemic amyloidosis.
Primary systemic amyloidosis is a rare disease. It primarily involves kidney, heart, peripheral nerves and liver. Intracutaneous hemorrhage manifesting in the form of petechiae, purpura and ecchymoses due to infiltration of blood vessel walls by amyloid deposits are the most common skin lesions. We report a case of primary systemic amyloidosis with multiple, non-itchy, papular lesions in lower eyelids and lower chest wall bilaterally. Diagnosis was confirmed in this case by biopsy of skin lesions using congo red staining. Papular eruptions as seen in index patient are relatively uncommon form of skin manifestations.
Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Susheel
S
Kumar
Rimi Som
RS
Sengupta
Nandita
N
Kakkar
Aman
A
Sharma
Surjit
S
Singh
Subhash
S
Varma