Synthesis and antifeedant activity of novel alpha-asarone derivatives against stored-product pests.
BACKGROUND
Alpha-asarone (2,4,5-trimethoxypropenylbenzene) derivatives represent a new series of compounds that possess good antifeedant activity against different stored-product pests.


RESULTS
A total of 23 novel alpha-asarone derivatives were synthesised and identified by (1) H NMR, (13) C NMR and IR, and their feeding deterrent activities were tested against Sitophilus granarius L., Trogoderma granarium Ev. and Tribolium confusum Duv. Ten compounds showed strong antifeedant activities.


CONCLUSIONS
Some of the title compounds displayed very good and broad-spectrum activities against adult and larval Coleoptera. The results indicate that the presence of a double bond in the side chain and three methoxy groups is important for antifeedant activity.
Plant Protection Institute - National Research Institute, Regional Experimental Station, Białystok, Poland.
Bożena
B
Łozowicka
Piotr
P
Kaczyński
D000081248:Allylbenzene Derivatives; D000818:Animals; D000840:Anisoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D001517:Coleoptera / Q000187:drug effects* / Q000502:physiology*; D005247:Feeding Behavior / Q000187:drug effects; D016266:Food Parasitology; D007306:Insecticides / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D015394:Molecular Structure
D000081248:Allylbenzene Derivatives; D000840:Anisoles; D007306:Insecticides; C012195:asarone
alpha-asarone derivatives; antifeedant activity; stored-product pests; synthesis