Cardiovascular-metabolic impact of adiponectin and aquaporin.
Visceral fat accumulation is located upstream of metabolic syndrome. Recent progress in adipocyte biology has clarified the molecular mechanism for pathophysiology of metabolic syndrome and its related disorders. In this review we summarize adiponectin and aquaporin 7 (AQP7) in the role of metabolic syndrome and cardiovascular diseases.
Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan. norikazu_maeda@endmet.med.osaka-u.ac.jp
Norikazu
N
Maeda
Tohru
T
Funahashi
Iichiro
I
Shimomura
D017667:Adipocytes / Q000502:physiology; D052242:Adiponectin / Q000097:blood / Q000235:genetics / Q000502:physiology*; D020346:Aquaporins / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D002319:Cardiovascular System / Q000503:physiopathology*; D005260:Female; D005786:Gene Expression Regulation; D006801:Humans; D050152:Intra-Abdominal Fat / Q000503:physiopathology; D008297:Male; D024821:Metabolic Syndrome / Q000503:physiopathology*; D009765:Obesity
C114141:AQP7 protein, human; C109669:AQP9 protein, human; D052242:Adiponectin; D020346:Aquaporins