Rare variations in IL36RN in severe adverse drug reactions manifesting as acute generalized exanthematous pustulosis.
Alexander A
AA
Navarini
Laurence
L
Valeyrie-Allanore
Niovi
N
Setta-Kaffetzi
Jonathan N
JN
Barker
Francesca
F
Capon
Daniel
D
Creamer
Jean-Claude
JC
Roujeau
Peggy
P
Sekula
Michael A
MA
Simpson
Richard C
RC
Trembath
Maja
M
Mockenhaupt
Catherine H
CH
Smith
D056150:Acute Generalized Exanthematous Pustulosis / Q000145:classification / Q000235:genetics*; D000369:Aged, 80 and over; D000658:Amoxicillin / Q000009:adverse effects; D002981:Clindamycin / Q000009:adverse effects; D064420:Drug-Related Side Effects and Adverse Reactions / Q000235:genetics*; D005260:Female; D014644:Genetic Variation / Q000235:genetics*; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D007378:Interleukins / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D020125:Mutation, Missense / Q000235:genetics*; D010894:Piroxicam / Q000009:adverse effects; D015398:Signal Transduction / Q000502:physiology
C122187:IL36RN protein, human; D007378:Interleukins; D010894:Piroxicam; D002981:Clindamycin; D000658:Amoxicillin