The stability of electrically induced ventricular fibrillation.
The first recorded heart rhythm for cardiac arrest patients can either be ventricular fibrillation (VF) which is treatable with a defibrillator, or asystole or pulseless electrical activity (PEA) which are not. The time course for the deterioration of VF to either asystole or PEA is not well understood. Knowing the time course of this deterioration may allow for improvements in emergency service delivery. In addition, this may improve the diagnosis of possible electrocutions from various electrical sources including utility power, electric fences, or electronic control devices (ECDs) such as a TASER(®) ECD. We induced VF in 6 ventilated swine by electrically maintaining rapid cardiac capture, with resulting hypotension, for 90 seconds. No circulatory assistance was provided. They were then monitored for 40 minutes via an electrode in the right ventricle. Only 2 swine remained in VF; 3 progressed to asystole; 1 progressed to PEA. These results were used in a logistic regression model. The results are then compared to published animal and human data. The median time for the deterioration of electrically induced VF in the swine was 35 minutes. At 24 minutes VF was still maintained in all of the animals. We conclude that electrically induced VF is long-lived--even in the absence of chest compressions.
Biomedical Engineering Dept., University of Minnesota, Minneapolis, MN, USA. kroll051@umn.edu
Mark W
MW
Kroll
Gregory P
GP
Walcott
Raymond E
RE
Ideker
Michael A
MA
Graham
Hugh
H
Calkins
Dhanunjaya
D
Lakkireddy
Richard M
RM
Luceri
Dorin
D
Panescu
D000818:Animals; D004195:Disease Models, Animal; D004566:Electrodes; D006801:Humans; D013552:Swine; D014693:Ventricular Fibrillation / Q000209:etiology / Q000503:physiopathology*