Subcorneal pustular dermatosis in childhood: a case report and review of the literature.
Subcorneal pustular dermatosis (SCPD, also known as Sneddon-Wilkinson disease) is a rare, benign, chronic, sterile pustular eruption which usually develops in middle-age or elderly women; it is rarely seen in childhood and adolescence. The primary lesions are pea-sized pustules classically described as half-pustular, half-clear flaccid blisters. Histologically the most important feature is a subcorneal accumulation of neutrophils with the absence of spongiosis or acantholysis, although acantholysis may be reported in older lesions. In this paper we present the case of a 7-year-old boy diagnosed with SCPD based on the characteristic clinical and histological features. Dapsone has been successfully used in the treatment of the disease.
Department of Dermatology, Federico II University, Via Pansini 5, 80131 Naples, Italy.
Massimiliano
M
Scalvenzi
Franco
F
Palmisano
Maria Carmela
MC
Annunziata
Ernesto
E
Mezza
Immacolata
I
Cozzolino
Claudia
C
Costa