Estimation of arterial baroreflex sensitivity in relation to carotid artery stiffness.
Arterial baroreflex has a significant role in regulating blood pressure. It is known that increased stiffness of the carotid sinus affects mecanotransduction of baroreceptors and therefore limits baroreceptors capability to detect changes in blood pressure. By using high resolution ultrasound video signal and continuous measurement of electrocardiogram (ECG) and blood pressure, it is possible to define elastic properties of artery simultaneously with baroreflex sensitivity parameters. In this paper dataset which consist 38 subjects, 11 diabetics and 27 healthy controls was analyzed. Use of diabetic and healthy test subjects gives wide scale of arteries with different elasticity properties, which provide opportunity to validate baroreflex and artery stiffness estimation methods.
Department of Applied Physics, Universityof Eastern Finland, Kuopio, Finland. jukka.lipponen@uef.fi
Jukka A
JA
Lipponen
Mika P
MP
Tarvainen
Tomi
T
Laitinen
Pasi A
PA
Karjalainen
Joonas
J
Vanninen
Timo
T
Koponen
Tiina
T
Lyyra-Laitinen
D000328:Adult; D017704:Baroreflex / Q000502:physiology*; D002339:Carotid Arteries / Q000503:physiopathology*; D016022:Case-Control Studies; D003920:Diabetes Mellitus / Q000503:physiopathology*; D004562:Electrocardiography; D006801:Humans; D008875:Middle Aged; D059289:Vascular Stiffness; D055815:Young Adult