Conjunctival hypertrophic scar following cryotherapy for retinopathy of prematurity.
A 6-year-old boy was referred to our hospital with symblepharon and lateral canthal deformity in both eyes, which developed 6 years ago. The patient was born at 27 weeks gestation. He had received cryotherapy for retinopathy of prematurity. One month after cryotherapy, he developed a conjunctival scar with symblepharon in both eyes and underwent symblepharon lysis at another hospital 5 years prior. Ocular examination revealed an extensive conjunctival hypertrophic scar with symblepharon and limitation of extraocular movements. An excisional biopsy, lateral canthoplasty, and symblepharon lysis with conjunctival autograft from the contralateral eye were performed in the left eye. Histopathologic examination revealed diffuse proliferation and infiltration of collagenous tissue.
Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
In Jeong
IJ
Lyu
Ho-Seok
HS
Sa
Kyung In
KI
Woo
Yoon-Duck
YD
Kim
D001706:Biopsy; D002648:Child; D017439:Cicatrix, Hypertrophic / Q000175:diagnosis / Q000209:etiology*; D003228:Conjunctiva / Q000473:pathology; D003229:Conjunctival Diseases / Q000175:diagnosis / Q000209:etiology*; D017679:Cryotherapy / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012178:Retinopathy of Prematurity / Q000628:therapy*
Cicatrix; Cryotherapy; Hypertrophic; Retinopathy of prematurity; Symblepharon