Hashimoto's thyroiditis in childhood: presentation modes and evolution over time.
Aim of this survey is to report the most recent views about Hashimoto's thyroiditis (HT) natural history according to the different presentations. In children presenting with either euthyroidism or subclinical hypothyroidism HT spontaneous course is frequently characterized by a trend towards deterioration of thyroid function, whereas in those presenting with overt hyperthyroidism a definitive resolution of hyperthyroid phase is to be expected. Another possible even though unusual outcome of HT is the conversion to Graves' disease.
Department of Pediatrics, University of Messina, Padiglione NI Policlinico Universitario, Via Consolare Valeria, 98125 Messina, Italy. filippo.deluca@unime.it
Filippo
F
De Luca
Simona
S
Santucci
Domenico
D
Corica
Elda
E
Pitrolo
Marika
M
Romeo
Tommaso
T
Aversa
D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D002648:Child; D003937:Diagnosis, Differential; D019317:Evidence-Based Medicine; D006111:Graves Disease / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D050031:Hashimoto Disease / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D006980:Hyperthyroidism / Q000175:diagnosis; D007037:Hypothyroidism / Q000175:diagnosis; D012307:Risk Factors; D013972:Thyrotropin / Q000097:blood; D013997:Time Factors
D015415:Biomarkers; D013972:Thyrotropin