[Proton beam radiotherapy of uveal melanoma--preliminary results].
OBJECTIVE
Presentation of the proton beam radiotherapy (PBR) as a method of treatment of the uveal melanoma patients in the Department of Ophthalmology and Ocular Oncology and Nuclear Physics Institute in Cracow, Poland and their preliminary results.


METHODS
Nine patients with only choroidal melanoma were treated using PBR between January and April 2011. There were 4 women (44%) and 5 men (56%), a mean age 56 years (38-72). The mean tumor thickness using ultrasounds was 4.14 mm (1.4-9.6 mm).


RESULTS
The mean follow-up was 6 months (5-7). The mean tumor thickness after PBR was 2.47 mm (0-9.3 mm). In 2 patients endoresection of irradiated tumor mass was performed with final flat scar. After exclusion of these patients from analysis, the mean thickness was 3.17 mm (1.5-9.3 mm). In 6 patients the visual function was stable.


CONCLUSIONS
The preliminary results show that PBR is highly precise method of uveal melanoma treatment achieving high rates of local control. This method necessitates a close co-operation between ophthalmologist, oncologist, radiotherapists, and medical physicist as well as an elaboration of own procedures of planning and treatment. uveal melanoma, radiotherapy, proton-beam radiotherapy.
Klinika Okulistyki i Onkologii Okulistycznej Katedry Okulistyki, Uniwersytetu Jagiellońskiego Collegium Medicum w Krakowie. bozena@romanowska.pl
Bozena
B
Romanowska-Dixon
Arkadiusz
A
Pogrzebielski
Anna
A
Bogdali
Anna
A
Markiewicz
Jan
J
Swakoń
Paweł
P
Olko
Marek
M
Jezabek
Beata
B
Sas-Korczyńska
Elzbieta
E
Pluta
D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D015353:Eye Enucleation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008545:Melanoma / Q000532:radiotherapy* / Q000601:surgery; D008875:Middle Aged; D061766:Proton Therapy; D011882:Radiotherapy, High-Energy / Q000379:methods*; D016896:Treatment Outcome; D014604:Uveal Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D014792:Visual Acuity; D000098943:Uveal Melanoma; D011522:Protons
D011522:Protons