[The antiradical activity of plant extracts and healthful preventive combinations of these exrtacts with the phospholipid complex].
Using the chemiluminescence method, the effective concentration of antioxidants (AO) and its reactivity toward peroxyl radicals (ARA, the k7 constant) have been measured for 13 plant extracts. In fact all extracts demonstrated ARA higher than ionol. Larix dahurica, Hypericum perforatum, Potentilla fruticosa, Aronia melanocarpa and Rhaponticum carthamoides extracts showed the highest values of ARA. The combinations Aronia + Raponticum extracts; Larix + Hibiscus extracts; Schizandra +Aronia extracts were synergistic (the synergism effect beta of 38%, 33% and 22%). Apparently this phenomenon is the result of the synergistic interaction between compounds present in plant extracts. The Phospholipid complex--Lipoid S40, lacting any antioxidant effect alone, showed a potent synergistic effect with Aronia extract (beta3 = 60%), Silybum extract (beta3 = 41%). Clinical trials demonstrated, that combinations "Lipoid + Aronia extract", "Lipoid + Larix extract + Hibiscus extract", "Lipoid + Silybum extract", "Lipoid + Q10 + Rosa majalis extract" may be used as an additional component in the medicinal treatment, or as an individual prophylactic agent.
V S
VS
Baranova
I F
IF
Rusina
D A
DA
Guseva
N N
NN
Prozorovskaia
O M
OM
Ipatova
O T
OT
Kasaikina
D000975:Antioxidants / Q000032:analysis* / Q000737:chemistry / Q000378:metabolism; D001663:Bilirubin / Q000378:metabolism; D002084:Butylated Hydroxytoluene / Q000737:chemistry / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000097:blood / Q000188:drug therapy*; D002784:Cholesterol / Q000097:blood; D002908:Chronic Disease; D006801:Humans; D020902:Hypericum / Q000737:chemistry; D043843:Leuzea / Q000737:chemistry; D008107:Liver Diseases / Q000188:drug therapy*; D008163:Luminescent Measurements; D017202:Myocardial Ischemia / Q000188:drug therapy; D010743:Phospholipids / Q000494:pharmacology* / Q000627:therapeutic use; D046936:Photinia / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D020011:Protective Agents / Q000494:pharmacology; D027824:Rosaceae / Q000737:chemistry; D032141:Schisandra / Q000737:chemistry; D014280:Triglycerides / Q000097:blood; D014570:Urologic Diseases / Q000188:drug therapy*
D000975:Antioxidants; D010743:Phospholipids; D010936:Plant Extracts; D020011:Protective Agents; D014280:Triglycerides; D002084:Butylated Hydroxytoluene; D002784:Cholesterol; D001663:Bilirubin