[Sesquiterpenes from stem of Schisandra glaucescens].
OBJECTIVE
To study the chemical constituents from Schisandra glaucescens.


METHODS
The chemical constituents were separated and purifed with silica gel, gel column chromatography preparative HPLC, and their structures were identified by such spectral methods as MS and NMR.


RESULTS
Twelve compounds were separated from petroleum ether fractions, and identified as t-cadinol (1), alpha-cadinol (2), torreyol (3), (+)-ent-epicubenol (4), ent-T-muurolol (5), (-)-15-hydroxycalamenene (6), (-)-cubebol (7), 4-epi-cubebol (8), caryophyllenol-I (9), caryophyllenol-II (10), oxyphyllenodiols A (11), caryolane-1,9/3-diol (12).


CONCLUSIONS
Compounds 4, 6-12 were separated from the genus for the first time, while compounds 1-12 were separated from this plant for the first time.
Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Pei-Pei
PP
Zhang
Sha-Sha
SS
Gao
Tian-Tian
TT
Zhang
Jia-Chun
JC
Chen
Hong-Quan
HQ
Duan
Jin-Bo
JB
Fang
D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry*; D032141:Schisandra / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry* / Q000302:isolation & purification
D004365:Drugs, Chinese Herbal; D012717:Sesquiterpenes