A biocompatible and bioactive replacement for dentine: is this a reality? The properties and uses of a novel calcium-based cement.
As part of the continuing evolution towards conservative dentistry there has been a drive to push further and investigate the possibility of inducing the repair and regeneration of lost dental hard tissue. Until recently, the prospect of repair and regeneration had been confined to laboratory studies and hypothesised scientific models. In 2009, a new product was launched claiming to be a revolutionary material capable of offering a bioactive and biocompatible replacement for dentine. The calcium-based cement is reported to preserve pulp vitality, promote pulp healing and provide a natural substitute for dentine through bioactive stimulation of the dentino-pulpal complex. Its clinical indications are extensive, described as a restorative material suitable for use wherever dentine replacement is required. In this article the physical, mechanical, chemical and biological properties of this novel material are presented, together with the results of experimental laboratory-based investigations and on-going clinical in vivo investigations.
Restorative Dentistry, Leeds Dental Institute. ishpinder.bachoo@gmail.com
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D001672:Biocompatible Materials / Q000737:chemistry*; D040761:Biomimetic Materials / Q000737:chemistry; D017610:Calcium Compounds / Q000737:chemistry*; D019245:Compressive Strength; D003460:Crystallization; D003461:Crystallography; D003738:Dental Cements / Q000737:chemistry*; D003763:Dental Leakage / Q000145:classification; D003782:Dental Pulp / Q000502:physiology; D003793:Dental Restoration, Permanent; D003804:Dentin / Q000502:physiology; D055119:Elastic Modulus; D006244:Hardness; D006801:Humans; D015394:Molecular Structure; D057872:Pulp Capping and Pulpectomy Agents / Q000737:chemistry; D012387:Root Canal Filling Materials / Q000737:chemistry; D017640:Silicates / Q000737:chemistry*; D013499:Surface Properties; D013997:Time Factors; D014945:Wound Healing / Q000502:physiology
D001672:Biocompatible Materials; D017610:Calcium Compounds; D003738:Dental Cements; D057872:Pulp Capping and Pulpectomy Agents; D012387:Root Canal Filling Materials; D017640:Silicates; C506393:tricalcium silicate