title: Alternaric acid: formal synthesis and related studies.
abstract: A silyl glyoxylate three-component-coupling methodology has been exploited to achieve a formal synthesis, an analogue to an intermediate in a distinct formal synthetic route, and a third (unique) approach to the natural product alternaric acid. Highlighted in this study is the versatility of silyl glyoxylates to engage a variety of nucleophile and electrophile pairs to provide wide latitude in the approach to complex molecule synthesis.
authors: Caudill Laboratories, Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290, USA.
authors: Michael C
authors: MC
authors: Slade
authors: Jeffrey S
authors: JS
authors: Johnson
keywords: formal synthesis; multicomponent coupling; natural products; silyl glyoxylates
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