title: [Innovations in the diagnosis and treatment of cholelithiasis].
abstract: OBJECTIVE
  To determine the density of densitometric gallstones and biliary sludge in order to clarify the possibility of lithotherapy in patients with gallstone disease (GSD).
  
  
  METHODS
  70 patients were carried out a comprehensive clinical examination with determination of densitometric density of gallstones and/or biliary sludge by means of computer tomography (CT), ultrasound of the abdomen, biochemical blood analysis. Assigned to the complex lithotherapy (Ursofalk and Kholit) in standard dosages, the results were evaluated in a year.
  
  
  RESULTS
  It was found that the density of bile in patients with GSD was ranging from +4 to +10 HU, sludge - +17,5 HU, gall stones - over +20 HU. The main factor of the exoediency of conservative therapy of GSD is to determine the density of gallstone by CT, which should not exceed +54 HU (+29,6 +/- 3,4 HU). Visualization of stones on CT is much higher (30%) than in Rg (10%), and its density is observed at more than +75,0 HU. Sludge particle less than 2.0 mm, but having a density more than +20,0 HU, should be viewed as a gallstone. Kholit, a herbal medicine, improves functional and structural indicators of biliary tract, digestive processes of cavity, and may be recommended as a monotherapy in stage I of GSD, as well as a component of combination therapy of cholelithiasis.
authors: R A
authors: RA
authors: Ivanchenkova
authors: A V
authors: AV
authors: Egorov
authors: A E
authors: AE
authors: Leonovich
authors: E R
authors: ER
authors: At'kova
mesh_terms: D015502:Absorptiometry, Photon; D001646:Bile / Q000737:chemistry / Q000000981:diagnostic imaging; D002756:Cholagogues and Choleretics / Q000008:administration & dosage / Q000627:therapeutic use; D002765:Cholecystography; D002769:Cholelithiasis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy*; D042882:Gallstones / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000628:therapy; D006801:Humans; D008096:Lithotripsy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014463:Ultrasonography; D014580:Ursodeoxycholic Acid / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D002756:Cholagogues and Choleretics; D014580:Ursodeoxycholic Acid