title: Predictors of the use of medications before and during pregnancy.
abstract: BACKGROUND
  Drug use in pregnancy is often reason of concern for mothers and their physicians. However, only few studies investigated predictors of drug use in pregnancy.
  
  
  OBJECTIVE
  To examine maternal characteristics as predictors of medication use in the 6 months before pregnancy and during the first 6 months of pregnancy. To examine whether prescription and over-the-counter (OTC) medication use in the 6 months before pregnancy had an impact on medication use in pregnancy.
  
  
  METHODS
  Six maternity care units and five community pharmacies.
  
  
  METHODS
  Data were collected using a specially designed self-reported questionnaire during the period March 2009-March 2010. Logistic regression was used to identify factors associated with medication use.
  
  
  METHODS
  Adjusted odds ratios (aOR) and 95% confidence intervals (CI) were used as association measures.
  
  
  RESULTS
  A total of 236 women were included in the analysis. After controlling for maternal characteristics, parity of more than one was associated with lower prescription medication use in pregnancy (aOR 0.46; 95% CI 0.22-0.93), higher household income with higher OTC medication use before pregnancy (aOR 3.13; 95% CI 1.22-8.00), and miscarriage with higher C and D Food and Drug Administration (FDA) risk category medication use in pregnancy (aOR 3.65; 95% CI 1.30-10.25). Prescription medication use before pregnancy was associated with higher prescription medication use in pregnancy (aOR 2.49; 95% CI 1.12-5.52), OTC medication use before pregnancy with higher OTC medication use in pregnancy (aOR 35.95; 95% CI 7.95-162.49), and C and D FDA risk category medication use before pregnancy with the same category medication use in pregnancy (aOR 3.54; 95% CI 1.23-10.17).
  
  
  CONCLUSIONS
  Different maternal characteristics were shown as predictors of medication use before and during pregnancy. However, medication use before pregnancy was shown as the most important predicting factor for the medication use in pregnancy.
authors: Department of Social Pharmacy and Pharmaceutical Legislation, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, 11221 Belgrade, Serbia.
authors: Marina
authors: M
authors: Odalovic
authors: Sandra
authors: S
authors: Vezmar Kovacevic
authors: Hedvig
authors: H
authors: Nordeng
authors: Katarina
authors: K
authors: Ilic
authors: Ana
authors: A
authors: Sabo
authors: Ljiljana
authors: L
authors: Tasic
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007182:Income / Q000706:statistics & numerical data; D016015:Logistic Models; D004366:Nonprescription Drugs / Q000145:classification / Q000627:therapeutic use*; D010298:Parity; D011247:Pregnancy; D055553:Prescription Drugs / Q000145:classification / Q000627:therapeutic use*; D055771:Serbia; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D004366:Nonprescription Drugs; D055553:Prescription Drugs
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