title: The effect of sleep-specific brain activity versus reduced stimulus interference on declarative memory consolidation.
abstract: Studies suggest that the consolidation of newly acquired memories and underlying long-term synaptic plasticity might represent a major function of sleep. In a combined repeated-measures and parallel-group sleep laboratory study (active waking versus sleep, passive waking versus sleep), we provide evidence that brief periods of daytime sleep (42.1 ± 8.9 min of non-rapid eye movement sleep) in healthy adolescents (16 years old, all female), compared with equal periods of waking, promote the consolidation of declarative memory (word-pairs) in participants with high power in the electroencephalographic sleep spindle (sigma) frequency range. This observation supports the notion that sleep-specific brain activity when reaching a critical dose, beyond a mere reduction of interference, promotes synaptic plasticity in a hippocampal-neocortical network that underlies the consolidation of declarative memory.
authors: Department of Psychiatry and Psychotherapy, University Medical Center Freiburg, Freiburg, Germany.
authors: Hannah
authors: H
authors: Piosczyk
authors: Johannes
authors: J
authors: Holz
authors: Bernd
authors: B
authors: Feige
authors: Kai
authors: K
authors: Spiegelhalder
authors: Friederike
authors: F
authors: Weber
authors: Nina
authors: N
authors: Landmann
authors: Marion
authors: M
authors: Kuhn
authors: Lukas
authors: L
authors: Frase
authors: Dieter
authors: D
authors: Riemann
authors: Ulrich
authors: U
authors: Voderholzer
authors: Christoph
authors: C
authors: Nissen
mesh_terms: D000293:Adolescent; D001921:Brain / Q000502:physiology*; D004569:Electroencephalography; D005260:Female; D006624:Hippocampus / Q000502:physiology; D006801:Humans; D061212:Memory, Episodic; D019579:Neocortex / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology; D017286:Polysomnography; D012890:Sleep / Q000502:physiology*; D012894:Sleep Stages / Q000502:physiology
keywords: declarative; interference; learning; memory consolidation; nap; sleep