title: Functionalized quantum dots for biosensing and bioimaging and concerns on toxicity.
abstract: Considerable efforts have been devoted to the development of novel functionalized nanomaterials for bio-oriented applications. With unique optical properties and molar scale production, colloidal photoluminescent quantum dots (QDs) have been properly functionalized with controlled interfaces as new class of optical probes with extensive use in biomedical research. In this review, we present a brief summary on the current research interests of using fine engineered QDs as a nanoplatform for biomedical sensing and imaging applications. In addition, recent concerns on the potential toxic effects of QDs are described as a general guidance for the development on QD formulations in future studies.
authors: School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, Singapore.
authors: Yucheng
authors: Y
authors: Wang
authors: Rui
authors: R
authors: Hu
authors: Guimiao
authors: G
authors: Lin
authors: Indrajit
authors: I
authors: Roy
authors: Ken-Tye
authors: KT
authors: Yong
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D055664:Electrochemical Techniques / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D057054:Molecular Imaging / Q000295:instrumentation / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry* / Q000633:toxicity; D045663:Quantum Dots