title: Single-incision laparoscopic versus traditional multiport laparoscopic colorectal surgery--a cumulative meta-analysis and systematic review.
abstract: OBJECTIVE
  The published data on the evaluation of feasibility and safety of single-incision laparoscopic colorectal surgery (SILC) compared with traditional multiport laparoscopic colorectal surgery (MLC) remained controversial. The present cumulative meta-analysis and systematic review were performed to provide a more objective and precise estimate.
  
  
  METHODS
  PubMed, the Cochrane Library, and also, manual searches were employed to identify potentially eligible studies which were published before June 7, 2012. The association was assessed by odds ratio (OR) and means with 95 % confidence intervals (CI).
  
  
  RESULTS
  A total of 20 comparative studies were included, with 670 patients underwent SILC and 838 patients underwent MLC. For overall pooled estimates, no evidence of between trial differences was found in overall conversion rate (OR, 1.7; 95 % CI, 0.97 to 3.01), overall complication rate (OR, 0.82; 95 % CI, 0.63 to 1.08), and operative time (mean, -3.59; 95 % CI, -10.95 to 3.77); significantly between trial differences were found in estimated blood loss (mean, -18.61; 95 % CI, -31.33 to -5.90) and post-operative hospital stay (mean, -0.54; 95 % CI, -0.95 to -0.12). The cumulative meta-analysis identified a potentially increased conversion rate of SILC compared with MLC with the increased percentage of malignancies, but no significant differences could be identified in overall complication rate.
  
  
  CONCLUSIONS
  This meta-analysis suggested the feasibility and safety of SILC performed by experienced hands, though potentially higher overall conversion rate occurred in malignancies. SILC will benefit the patients much more with its superiority over MLC.
authors: Biliary and Vascular Unit, Department of General Surgery, Shengjing Hospital, China Medical University, Shenyang 110004, People's Republic of China.
authors: Chao
authors: C
authors: Lv
authors: Shuodong
authors: S
authors: Wu
authors: Yuli
authors: Y
authors: Wu
authors: Jingpu
authors: J
authors: Shi
authors: Yang
authors: Y
authors: Su
authors: Ying
authors: Y
authors: Fan
authors: Jing
authors: J
authors: Kong
authors: Xiaopeng
authors: X
authors: Yu
mesh_terms: D003107:Colorectal Surgery / Q000009:adverse effects; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects; D007902:Length of Stay; D011183:Postoperative Complications / Q000209:etiology; D017594:Publication Bias; D016896:Treatment Outcome
references: Int J Colorectal Dis. 2008 Oct;23(10):1013-6
references: 18607608
references: Tech Coloproctol. 2011 Dec;15(4):397-401
references: 21887555
references: Dis Colon Rectum. 2012 Feb;55(2):140-6
references: 22228156
references: BMC Med Res Methodol. 2005 Apr 20;5:13
references: 15840177
references: Dis Colon Rectum. 2011 Feb;54(2):187-92
references: 21228667
references: Surg Endosc. 2010 Dec;24(12):3233-6
references: 20464415
references: Colorectal Dis. 2012 Jun;14(6):671-83
references: 21689339
references: Colorectal Dis. 2012 Sep;14(9):1138-44
references: 22122854
references: Colorectal Dis. 2011 Apr;13(4):393-8
references: 20002691
references: Surg Endosc. 2012 Oct;26(10):2729-34
references: 22538676
references: Colorectal Dis. 2012 Oct;14(10):e643-54
references: 22632808
references: Colorectal Dis. 2012 Apr;14(4):e171-6
references: 21914101
references: J Gastrointest Surg. 2011 Nov;15(11):1989-94
references: 21796459
references: World J Surg. 2011 Apr;35(4):873-80
references: 21318430
references: Surg Endosc. 2012 Jan;26(1):96-102
references: 21792717
references: Surgery. 2011 Oct;150(4):820-7
references: 22000196
references: Control Clin Trials. 1986 Sep;7(3):177-88
references: 3802833
references: Ann Surg. 2011 Dec;254(6):933-40
references: 22107740
references: Int J Colorectal Dis. 2011 Apr;26(4):415-21
references: 21174107
references: J Am Coll Surg. 2011 Jul;213(1):72-80; discussion 80-2
references: 21420878
references: Br J Surg. 2010 Dec;97(12):1881-3
references: 20872555
references: Dis Colon Rectum. 2011 Nov;54(11):1355-61
references: 21979178
references: Med Oncol. 2011 Dec;28(4):925-33
references: 20458560
references: Dig Dis Sci. 2012 Aug;57(8):2103-12
references: 22466079
references: Dis Colon Rectum. 2010 Jun;53(6):944-8
references: 20485010
references: Dis Colon Rectum. 2011 Feb;54(2):183-6
references: 21228666
references: Colorectal Dis. 2012 May;14(5):634-41
references: 21752175
references: Tech Coloproctol. 2012 Dec;16(6):423-8
references: 22614072
references: Br J Surg. 2010 Dec;97(12):1884
references: 21058353
references: Dis Colon Rectum. 2010 Nov;53(11):1549-54
references: 20940605
references: Am J Surg. 2010 Jul;200(1):144-61
references: 20637347
references: Surg Laparosc Endosc. 1991 Sep;1(3):144-50
references: 1688289
references: Surg Endosc. 2012 May;26(5):1403-11
references: 22101420
references: Surg Endosc. 2011 Jun;25(6):1887-92
references: 21359907
references: Ann Surg. 2012 Apr;255(4):667-76
references: 22258065
references: J Minim Access Surg. 2011 Jan;7(1):52-60
references: 21197243
references: Am J Surg. 2012 Jul;204(1):115-20
references: 22178484
references: Dis Colon Rectum. 2010 Nov;53(11):1467-72
references: 20940593
references: Minim Invasive Surg. 2012;2012:874172
references: 22567227
references: Colorectal Dis. 2012 Oct;14(10):1267-75
references: 22309248
references: JSLS. 2004 Oct-Dec;8(4):352-5
references: 15554279
references: Dis Colon Rectum. 2012 Feb;55(2):134-9
references: 22228155
references: Surg Endosc. 2011 Nov;25(11):3559-65
references: 21638180
references: J Gastrointest Surg. 2012 Mar;16(3):629-34
references: 22125169
references: Ann Surg. 2012 Jan;255(1):66-9
references: 22104563
references: PLoS One. 2012;7(4):e35292
references: 22532846
references: J Gastrointest Surg. 2012 Apr;16(4):849-56
references: 22125171
references: Surg Endosc. 2008 May;22(5):1146-60
references: 18071810
references: Surg Endosc. 2011 Mar;25(3):835-40
references: 20734083
references: Dis Colon Rectum. 2011 Jun;54(6):705-10
references: 21552055