title: Additional effects of taurine on the benefits of BCAA intake for the delayed-onset muscle soreness and muscle damage induced by high-intensity eccentric exercise.
abstract: Taurine (TAU) has a lot of the biological, physiological, and pharmocological functions including anti-inflammatory and anti-oxidative stress. Although previous studies have appreciated the effectiveness of branched-chain amino acids (BCAA) on the delayed-onset muscle soreness (DOMS), consistent finding has not still convinced. The aim of this study was to examine the additional effect of TAU with BCAA on the DOMS and muscle damages after eccentric exercise. Thirty-six untrained male volunteers were equally divided into four groups, and ingested a combination with 2.0 g TAU (or placebo) and 3.2 g BCAA (or placebo), thrice a day, 2 weeks prior to and 4 days after elbow flexion eccentric exercise. Following the period after eccentric exercise, the physiological and blood biochemical markers for DOMS and muscle damage showed improvement in the combination of TAU and BCAA supplementation rather than in the single or placebo supplementations. In conclusion, additional supplement of TAU with BCAA would be a useful way to attenuate DOMS and muscle damages induced by high-intensity exercise.
authors: Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan. ra.song.gyu@gmail.com
authors: Song-Gyu
authors: SG
authors: Ra
authors: Teruo
authors: T
authors: Miyazaki
authors: Keisuke
authors: K
authors: Ishikura
authors: Hisashi
authors: H
authors: Nagayama
authors: Takafumi
authors: T
authors: Suzuki
authors: Seiji
authors: S
authors: Maeda
authors: Masaharu
authors: M
authors: Ito
authors: Yasushi
authors: Y
authors: Matsuzaki
authors: Hajime
authors: H
authors: Ohmori
mesh_terms: D000597:Amino Acids, Branched-Chain / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D019540:Area Under Curve; D015415:Biomarkers / Q000097:blood; D015444:Exercise; D005247:Feeding Behavior / Q000187:drug effects; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D018908:Muscle Weakness / Q000097:blood / Q000188:drug therapy* / Q000201:enzymology; D018482:Muscle, Skeletal / Q000187:drug effects / Q000473:pathology*; D010147:Pain Measurement; D013654:Taurine / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D000597:Amino Acids, Branched-Chain; D015415:Biomarkers; D013654:Taurine; D007770:L-Lactate Dehydrogenase