title: Histiocytic sarcoma of the nasal cavity in a horse.
abstract: Histiocytic diseases in veterinary medicine have been revised in the last few decades, but these are considered relatively rare in horses. This report describes a 9-year-old female horse, Dutch Warmblood, presented for investigation of severe nasal bleeding. A multinodular bilateral mass of 5 cm, reddish to white in color, that invaded and destroyed the surrounding tissues, was observed during a clinical examination of the nostril The morphological features of the tumor cells were represented by cytologically bizarre, highly phagocytic, multinucleated giant cells. These findings, together with immunohistochemical results allowed a diagnosis of histiocytic sarcoma.
authors: Department of Pathology and Animal Health, University of Naples Federico II, Naples, Italy. paciello@unina.it
authors: O
authors: O
authors: Paciello
authors: G
authors: G
authors: Passantino
authors: A
authors: A
authors: Costagliola
authors: S
authors: S
authors: Papparella
authors: A
authors: A
authors: Perillo
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D005260:Female; D054747:Histiocytic Sarcoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D006734:Horse Diseases / Q000175:diagnosis / Q000473:pathology*; D006736:Horses; D009296:Nasal Cavity / Q000473:pathology*; D009669:Nose Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*