title: A mixed incoherent feed-forward loop contributes to the regulation of bacterial photosynthesis genes.
abstract: Living cells use a variety of regulatory network motifs for accurate gene expression in response to changes in their environment or during differentiation processes. In Rhodobacter sphaeroides, a complex regulatory network controls expression of photosynthesis genes to guarantee optimal energy supply on one hand and to avoid photooxidative stress on the other hand. Recently, we identified a mixed incoherent feed-forward loop comprising the transcription factor PrrA, the sRNA PcrZ and photosynthesis target genes as part of this regulatory network. This point-of-view provides a comparison to other described feed-forward loops and discusses the physiological relevance of PcrZ in more detail.
authors: Institut für Mikrobiologie und Molekularbiologie; Universität Giessen; Giessen, Germany.
authors: Nils N
authors: NN
authors: Mank
authors: Bork A
authors: BA
authors: Berghoff
authors: Gabriele
authors: G
authors: Klug
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D053263:Gene Regulatory Networks; D005798:Genes, Bacterial; D018384:Oxidative Stress / Q000235:genetics; D010788:Photosynthesis / Q000235:genetics*; D012329:RNA, Bacterial / Q000378:metabolism; D058727:RNA, Small Untranslated / Q000378:metabolism*; D012242:Rhodobacter sphaeroides / Q000235:genetics* / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D012329:RNA, Bacterial; D058727:RNA, Small Untranslated; D014157:Transcription Factors
keywords: Rhodobacter; feed-forward loop; gene regulation; oxygen tension; photosynthesis; redox regulation; small RNAs
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