title: Scabies increased the risk of chronic kidney disease: a 5-year follow-up study.
abstract: BACKGROUND
  The most documented complication of scabies has been reported to be infection by group A streptococci, which has in turn been suggested to contribute to the development of glomerulonephritis.
  
  
  OBJECTIVE
  This study aimed to investigate the risk of chronic kidney disease (CKD) subsequent to scabies utilizing a population-based dataset in Taiwan.
  
  
  METHODS
  This retrospective matched-cohort study included 5071 subjects with scabies and 25 355 randomly selected comparison subjects. We individually tracked each subject for a 5-year period to identify those who subsequently received a diagnosis of CKD during the follow-up period. Stratified Cox proportional hazards regressions were performed to compute the hazard ratio (HR) of CKD during the 5-year follow-up period.
  
  
  RESULTS
  The incidence rate of CKD during the 5-year follow-up period was 9.66 (8.51-10.93) per 1,000 person-years and 6.24 (5.82-6.69) per 1000 person-years for subjects with and without scabies respectively. The HR for CKD during the 5-year follow-up period for subjects with scabies was 1.34 (95% CI = 1.15-1.56) that of comparison subjects after adjusting for monthly income, hypertension, diabetes, obesity, stroke, coronary heart disease, chronic obstructive pulmonary disease, tobacco use disorder, hyperlipidemia and alcohol abuse during the 5-year follow-up period. Male subjects with scabies were 1.40 (95% CI = 1.14-1.71) times more likely than comparison subjects to suffer from subsequent CKD, and female study subjects were 1.27 (95% CI = 1.05-1.61) times more likely.
  
  
  CONCLUSIONS
  We concluded that there was an increased risk for CKD among patients suffering from scabies.
authors: Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan; School of Health Care Administration, Taipei Medical University, Taipei, Taiwan.
authors: S-D
authors: SD
authors: Chung
authors: K-H
authors: KH
authors: Wang
authors: C-C
authors: CC
authors: Huang
authors: H-C
authors: HC
authors: Lin
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D012532:Scabies / Q000150:complications*; D013624:Taiwan / Q000453:epidemiology