title: Ultrasound guided fine-needle aspiration cytology of breast lesions.
abstract: Breast biopsy consists in the collection of cells or tissue fragments from a breast lesion and their analysis by a pathologist. There are several types of breast biopsy defined on the basis of the type of needle used: fine-needle aspiration and biopsy performed with a spring-based needle. This article focuses on fine-needle aspiration performed under sonographic guidance.It is used mainly to assess cysts that appear to contain vegetations or blood or that are associated with symptoms; lesions and solid nodules that are not unequivocally benign; and axillary lymph nodes that appear suspicious on physical examination and/or sonography.In addition to distinguishing between benign and malignant lesions, ultrasound guided fine-needle aspiration also plays an important role in tumor grading and in immunocytochemical identifying specific tumor markers. This article describes the technique used and the possible causes of false negative and false positive findings. Despite its limitations, fine-needle aspiration has become a fundamental tool for the identification and preoperative management of malignant breast lesions.
authors: IRCCS Foundation, San Matteo Medical Center, Institute of Radiology, University of Pavia, Italy.
authors: C
authors: C
authors: Pagani
authors: D R
authors: DR
authors: Coscia
authors: C
authors: C
authors: Dellabianca
authors: M
authors: M
authors: Bonardi
authors: S
authors: S
authors: Alessi
authors: F
authors: F
authors: Calliada
keywords: Breast; Fine-needle biopsy; Ultrasonography
references: Clin Radiol. 2010 Apr;65(4):259-70
references: 20338392
references: Acta Cytol. 1994 Nov-Dec;38(6):969-70
references: 7992589
references: Eur Radiol. 2008 Sep;18(9):1761-73
references: 18414872
references: Semin Roentgenol. 2011 Jan;46(1):51-9
references: 21134528
references: Diagn Cytopathol. 1993;9(1):106-12
references: 8458274
references: Pathol Annu. 1989;24 Pt 2:23-62
references: 2671883
references: Cancer. 1993 Sep 1;72(5):1642-51
references: 8348496
references: Acta Cytol. 1986 Mar-Apr;30(2):135-46
references: 3008470
references: Am J Clin Pathol. 1992 Aug;98(2):145-7
references: 1510027
references: Am J Clin Pathol. 1988 Jun;89(6):707-13
references: 2835896
references: Acta Cytol. 1994 Nov-Dec;38(6):898-908
references: 7992576
references: Acta Cytol. 1992 Mar-Apr;36(2):199-202
references: 1311886
references: Verh Dtsch Ges Pathol. 2005;89:35-44
references: 18035670
references: Cancer. 1987 Oct 15;60(8):1866-71
references: 3652014
references: Cancer. 1992 Apr 15;69(8):2104-10
references: 1544116
references: Cytopathology. 1991;2(4):167-76
references: 1954318
references: J Ultrasound. 2011 Jun;14(2):55-65
references: 23396888
references: Histopathology. 1991 Nov;19(5):403-10
references: 1757079
references: Tumori. 1985 Apr 30;71(2):179-85
references: 4002348
references: Surg Gynecol Obstet. 1957 Jul;105(1):97-102
references: 13442910
references: J Ultrasound. 2010 Sep;13(3):126-33
references: 23396633
references: J Ultrasound. 2011 Jun;14(2):47-54
references: 23396620
references: Semin Ultrasound CT MR. 2006 Aug;27(4):298-307
references: 16915998