title: [Pertussis in a 4-month-old infant with unrecognized cystic fibrosis].
abstract: We present a case report of a small boy with cystic fibrosis complicated by pertussis and pneumothorax. The child had not been vaccinated against Bordetella pertussis due to the failure to thrive and was infected with the bacterium at the age of 4 months. The course of the disease was severe, with respiratory distress and spontaneous pneumothorax. The diagnosis of pertussis was serologically confirmed. A suspicion for cystic fibrosis increased after an unusually prolonged course of the disease and a history of the failure to thrive. A comprehensive diagnostic procedure revealed Pseudomonas aeruginosa respiratory infection, anemia, pancreatic insufficiency, a positive sweat test and the presence of two CFTR gene mutations. The patient, treated with comprehensive cystic fibrosis therapy, recovered from acute respiratory illness and started to thrive soon.
authors: Clinic of Pediatric Infectious Diseases, The University Hospital Brno, Czech Republic. lhomola@fnbrno.cz
authors: Lukáš
authors: L
authors: Homola
authors: Alena
authors: A
authors: Holčíková
authors: Eliška
authors: E
authors: Zárošská
authors: Lenka
authors: L
authors: Krbková
authors: Renata
authors: R
authors: Gaillyová
authors: Markéta
authors: M
authors: Hanslianová
authors: Pavla
authors: P
authors: Cižmářová
mesh_terms: D003550:Cystic Fibrosis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007223:Infant; D008297:Male; D011030:Pneumothorax / Q000150:complications; D014917:Whooping Cough / Q000150:complications* / Q000175:diagnosis