title: Affect and craving: positive and negative affect are differentially associated with approach and avoidance inclinations.
abstract: BACKGROUND
  Research on reactivity to alcohol and drug cues has either ignored affective state altogether or has focused rather narrowly on the role of negative affect in craving. Moreover, until recently, the relevant analyses of affect and craving have rarely addressed the ambivalence often associated with craving itself. The current study investigated how both negative and positive affect moderate approach and avoidance inclinations associated with cue-elicited craving in a clinical sample diagnosed with substance use disorders.
  
  
  METHODS
  One hundred forty-four patients (age range of 18-65, mean 42.0; n=92 males) were recruited from an inpatient detoxification unit for substance abuse. Participants completed a baseline assessment of both positive and negative affect prior to completing a cue-reactivity paradigm for which they provided self-report ratings of inclinations to approach (use) and avoid (not use) alcohol, cigarettes, and non-psychoactive control substances (food and beverages).
  
  
  RESULTS
  Participants with elevated negative affect reported significantly higher approach ratings for cigarette and alcohol cues, whereas those high in positive affect showed significantly higher levels of avoidance inclinations for both alcohol and cigarette cues and also significantly lower approach ratings for alcohol cues, all relative to control cues.
  
  
  CONCLUSIONS
  Results for negative affect are consistent with previous cue reactivity research, whereas results for positive affect are unique and call attention to its clinical potential for attenuating approach inclinations to substance use cues. Further, positive affect was related to both approach and avoidance inclinations, underscoring the utility of a multidimensional conceptualization of craving in the analysis.
authors: Research Institute on Addictions, University at Buffalo, 1021 Main St., Buffalo, NY 14203, United States. rschlauch@ria.buffalo.edu
authors: Robert C
authors: RC
authors: Schlauch
authors: Daniel
authors: D
authors: Gwynn-Shapiro
authors: Paul R
authors: PR
authors: Stasiewicz
authors: Danielle S
authors: DS
authors: Molnar
authors: Alan R
authors: AR
authors: Lang
mesh_terms: D000293:Adolescent; D000328:Adult; D000339:Affect; D000368:Aged; D002492:Central Nervous System Depressants / Q000009:adverse effects*; D003463:Cues; D000431:Ethanol / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012114:Residential Treatment; D013375:Substance Withdrawal Syndrome / Q000209:etiology / Q000523:psychology*; D062789:Tobacco Products / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D002492:Central Nervous System Depressants; D000431:Ethanol
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