title: Dysbiosis in ukrainian children with irritable bowel syndrome affected by natural radiation.
abstract: OBJECTIVE
  Microbiota has an important role in human metabolism, nutrition, immunity, and protection against colonization by pathogenic microorganisms. Radiation can harm the beneficial members of the gastrointestinal tract flora.
  
  
  METHODS
  Our study included 75 rural children aged 4-18 years, who lived in contaminated area exposed to natural environmental radiation with clinical symptoms of irritable bowel syndrome and 20 healthy urban participants aged 5-15 as control group. The intestinal bacterial microbiota was examined from stool samples.
  
  
  RESULTS
  Our results indicated the population levels of microbiota such as Enterobacter, Enterococcus, Lactobacillus and Bifidbacterium in caecal contents in 61 subjects (81.3%) was significantly less than in control group.
  
  
  CONCLUSIONS
  We investigated alternation of the intestinal microbiota affected by ionizing radiation in children with clinical symptoms of irritable bowel syndrome.
authors: Department of Clinical Immunology & Allergology, National Medical Academy for Post Graduate Education, Kiev, Ukraine ; Ukrainian Specialized Dispensaries of Radiation Defend Population, Kiev, Ukraine.
authors: Mohammad-Reza
authors: MR
authors: Sheikh Sajjadieh
authors: Larisa V
authors: LV
authors: Kuznetsova
authors: Vadim B
authors: VB
authors: Bojenko
keywords: Immune Status; Irritable Bowel Syndrome; Microbiota
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