title: Medical emergency team involvement in patients hospitalized with acute myeloid leukemia.
abstract: Patients with acute myeloid leukemia (AML) are at risk for sudden clinical deterioration. We aimed to describe the incidence of medical emergency team (MET) activation, intensive care unit (ICU) admissions and outcomes for patients with AML. We performed a 5-year retrospective cohort study of patients hospitalized with AML. One hundred and seventy patients were divided into three groups: (1) MET activated (n = 34); (2) MET criteria present but MET not activated (n = 17); and (3) all other patients with AML (n = 119). MET activation incidence was 200 calls/1000 admissions (95% confidence interval [CI], 138-279), compared with a hospital-wide rate of 29.3 calls/1000 admissions (95% CI, 28.2-30.4) (relative risk 6.90; 95% CI, 4.77-9.67, p < 0.0001). Some 77% (n = 26) were triaged to the ICU. Hospital mortality was higher in MET activated and MET fulfilled without activation groups compared with all others (27% vs. 12% vs. 7%, p = 0.007). Changes to goals of care were more common with MET activation. Patients with AML commonly receive MET activation. Approximately one in 10 fulfill MET criteria, however do not receive MET activation.
authors: Division of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta , Edmonton , Canada.
authors: Ambica
authors: A
authors: Parmar
authors: Heather
authors: H
authors: Richardson
authors: David
authors: D
authors: McKinlay
authors: R T Noel
authors: RT
authors: Gibney
authors: Sean M
authors: SM
authors: Bagshaw
mesh_terms: D000328:Adult; D000368:Aged; D003422:Critical Care; D004636:Emergency Service, Hospital; D005260:Female; D057209:Hospital Rapid Response Team; D006801:Humans; D007362:Intensive Care Units; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome