title: Detection of correct and incorrect measurements in real-time continuous glucose monitoring systems by applying a postprocessing support vector machine.
abstract: Support vector machines (SVMs) are an attractive option for detecting correct and incorrect measurements in real-time continuous glucose monitoring systems (RTCGMSs), because their learning mechanism can introduce a postprocessing strategy for imbalanced datasets. The proposed SVM considers the geometric mean to obtain a more balanced performance between sensitivity and specificity. To test this approach, 23 critically ill patients receiving insulin therapy were monitored over 72 h using an RTCGMS, and a dataset of 537 samples, classified according to International Standards Organization (ISO) criteria (372 correct and 165 incorrect measurements), was obtained. The results obtained were promising for patients with septic shock or with sepsis, for which the proposed system can be considered as reliable. However, this approach cannot be considered suitable for patients without sepsis.
authors: Institute of Informatics and Applications, University of Girona, Girona 17071, Spain. yennyteresa.leal@udg.edu
authors: Yenny
authors: Y
authors: Leal
authors: Luis
authors: L
authors: Gonzalez-Abril
authors: Carol
authors: C
authors: Lorencio
authors: Jorge
authors: J
authors: Bondia
authors: Josep
authors: J
authors: Vehi
mesh_terms: D000368:Aged; D000465:Algorithms; D001786:Blood Glucose / Q000032:analysis*; D003199:Computer Systems; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004360:Drug Therapy, Computer-Assisted / Q000379:methods; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy*; D007004:Hypoglycemic Agents / Q000008:administration & dosage; D007328:Insulin / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D060388:Support Vector Machine
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin