title: Phylogeographic patterns of mtDNA variation revealed multiple glacial refugia for the frog species Feirana taihangnica endemic to the Qinling Mountains.
abstract: Diversification patterns and demography of montane species are affected by Pleistocene climate fluctuations. Empirical cases from the Qinling Mountains (QM) region, which is a major biogeographic divider of East Asia, are few. We used DNA sequence data of the complete mitochondrial ND2 gene to detect effects of the Pleistocene glaciations on phylogeographic profiles of a frog species, Feirana taihangnica, which is endemic to the QM. Four distinct lineages consisting of seven sublineages were revealed. The strongest signal of biogeographical structure (F(ct) = 0.971, P < 0.01) was found when populations were grouped according to these seven sublineages. One narrow secondary contact zone was detected in the middle QM between the lineage from middle QM and the lineage from eastern QM. Coalescent simulations indicated that this species colonized the QM region by a stepping-stone model. Divergences among lineages had likely been influenced by the uplift of the Tibetan Plateau during the late Miocene-to-late Pleistocene, as well as by the Pleistocene climatic cycles. Coalescent simulations also suggested that F. taihangnica populations have persisted through the Pleistocene glacial periods in multiple refugia across the QM region. Demographic analyses indicated that all lineages, except the lineage in the Funiu Mountains, have been experienced postglacial expansion of population size and distribution range. In conclusion, Pleistocene climate fluctuations and tectonic changes during the late Miocene-late Pleistocene have profoundly influenced the phylogeography and historical demography of F. taihangnica.
authors: Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.
authors: Bin
authors: B
authors: Wang
authors: Jianping
authors: J
authors: Jiang
authors: Feng
authors: F
authors: Xie
authors: Cheng
authors: C
authors: Li
mesh_terms: D000064:Acclimatization / Q000235:genetics*; D000531:Altitude; D000818:Animals; D001001:Anura / Q000235:genetics*; D003081:Cold Climate; D004272:DNA, Mitochondrial / Q000235:genetics*; D017753:Ecosystem; D005202:Asia, Eastern; D049810:Genetic Speciation; D014644:Genetic Variation / Q000502:physiology*; D046448:Ice Cover; D010802:Phylogeny; D058974:Phylogeography; D013045:Species Specificity
chemical_list: D004272:DNA, Mitochondrial
references: BMC Evol Biol. 2009 Jun 27;9:143
references: 19558699
references: PLoS Biol. 2006 May;4(5):e88
references: 16683862
references: Mol Phylogenet Evol. 2008 Mar;46(3):1049-70
references: 18055224
references: Nature. 2004 Aug 19;430(7002):851-6
references: 15318212
references: Bioinformatics. 2003 Aug 12;19(12):1572-4
references: 12912839
references: Genetics. 2007 Jun;176(2):969-81
references: 17409067
references: Philos Trans R Soc Lond B Biol Sci. 2004 Feb 29;359(1442):183-95; discussion 195
references: 15101575
references: J Mol Evol. 2003 Dec;57(6):636-41
references: 14745532
references: Evolution. 2007 Jun;61(6):1439-54
references: 17542851
references: Zoolog Sci. 2009 Jul;26(7):500-9
references: 19663646
references: Evolution. 2006 Dec;60(12):2604-21
references: 17263120
references: Mol Ecol. 2005 Sep;14(10):3049-65
references: 16101773
references: PLoS One. 2012;7(7):e41579
references: 22848532
references: PLoS One. 2012;7(4):e34955
references: 22523566
references: Genetics. 1997 Oct;147(2):915-25
references: 9335623
references: Mol Ecol. 2009 Jul;18(13):2877-96
references: 19500257
references: Mol Phylogenet Evol. 1999 Aug;12(3):320-32
references: 10413626
references: Mol Ecol. 2004 Sep;13(9):2557-66
references: 15315670
references: Nature. 2000 Jun 22;405(6789):907-13
references: 10879524
references: Mol Ecol. 2002 Dec;11(12):2623-35
references: 12453245
references: Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10597-602
references: 10485871
references: Bioinformatics. 2009 Jun 1;25(11):1451-2
references: 19346325
references: Mol Phylogenet Evol. 2001 Mar;18(3):434-48
references: 11277635
references: Genetics. 1943 Mar;28(2):114-38
references: 17247074
references: Mol Biol Evol. 2003 Jan;20(1):76-86
references: 12519909
references: Hum Biol. 1994 Aug;66(4):591-600
references: 8088750
references: Mol Phylogenet Evol. 1998 Aug;10(1):118-31
references: 9751922
references: Mol Ecol. 2001 Mar;10(3):691-701
references: 11298980
references: Mol Biol Evol. 1996 Sep;13(7):895-902
references: 8751998
references: Zoolog Sci. 2005 Mar;22(3):353-62
references: 15795498
references: Mol Biol Evol. 2008 Jul;25(7):1253-6
references: 18397919
references: Science. 2001 Jun 22;292(5525):2323-5
references: 11423661
references: Genetics. 1994 Feb;136(2):673-83
references: 8150290
references: Proc Biol Sci. 1998 Mar 22;265(1395):457-63
references: 9569664
references: Syst Biol. 2002 Feb;51(1):44-68
references: 11943092
references: Mol Ecol. 2008 Apr;17(8):1971-82
references: 18363665
references: Hum Biol. 2004 Apr;76(2):173-90
references: 15359530
references: Evolution. 2000 Aug;54(4):1337-48
references: 11005300
references: Evolution. 2000 Aug;54(4):1092-101
references: 11005279
references: Heredity (Edinb). 2000 Mar;84 ( Pt 3):362-72
references: 10762406
references: Evolution. 2006 May;60(5):1004-13
references: 16817540
references: Mol Ecol. 2011 May;20(9):1905-22
references: 21438932
references: BMC Evol Biol. 2007 Nov 08;7:214
references: 17996036
references: BMC Evol Biol. 2010 Jul 10;10:208
references: 20618977
references: Evolution. 1999 Apr;53(2):313-318
references: 28565409
references: Mol Phylogenet Evol. 1998 Feb;9(1):80-7
references: 9479697
references: Genetics. 1992 Oct;132(2):619-33
references: 1385266
references: Mol Biol Evol. 1992 May;9(3):552-69
references: 1316531
references: Mol Biol Evol. 1992 Mar;9(2):366-9
references: 1560769
references: Syst Biol. 2003 Oct;52(5):696-704
references: 14530136
references: Mol Ecol. 2010 Jan;19(2):338-51
references: 20002586
references: Genetics. 1992 Jun;131(2):479-91
references: 1644282
references: Proc Biol Sci. 1998 Sep 22;265(1407):1707-12
references: 9787467
references: Proc Biol Sci. 2007 Nov 7;274(1626):2653-60
references: 17725978
references: Mol Phylogenet Evol. 2001 Apr;19(1):131-43
references: 11286498
references: Genetics. 1989 Nov;123(3):603-13
references: 2599370
references: Genet Mol Res. 2006 Jul 31;5(3):466-74
references: 17117361
references: Evolution. 2000 Dec;54(6):1839-54
references: 11209764
references: Syst Biol. 2000 Sep;49(3):400-21
references: 12116419
references: BMC Genet. 2005 Mar 11;6:13
references: 15760479
references: Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13765-70
references: 20643945
references: BMC Evol Biol. 2008 Jan 24;8:21
references: 18215328
references: Evolution. 1985 Jul;39(4):783-791
references: 28561359
references: Nature. 2001 May 3;411(6833):62-6
references: 11333976
references: Mol Ecol. 2009 Feb;18(4):622-33
references: 19215583
references: Nature. 2000 Sep 14;407(6801):180-2
references: 11001054
references: Mol Biol Evol. 2005 May;22(5):1185-92
references: 15703244
references: Mol Biol Evol. 1995 Sep;12(5):887-92
references: 7476134
references: Mol Phylogenet Evol. 2007 Jan;42(1):193-212
references: 16934495
references: Ecology. 2008 Nov;89(11 Suppl):S108-22
references: 19097488
references: Mol Ecol. 2005 Oct;14(12):3745-55
references: 16202093
references: Mol Ecol. 2000 Oct;9(10):1657-9
references: 11050560
references: Mol Biol Evol. 2010 Mar;27(3):570-80
references: 19906793
references: Mol Phylogenet Evol. 2008 Aug;48(2):543-53
references: 18539486
references: Mol Phylogenet Evol. 2009 Jan;50(1):59-73
references: 18992827
references: Genetics. 1989 Nov;123(3):585-95
references: 2513255
references: J Mol Evol. 1993 Sep;37(3):240-4
references: 8230248
references: Nucleic Acids Res. 1997 Dec 15;25(24):4876-82
references: 9396791
references: Science. 1960 Apr 29;131(3409):1292-7
references: 14399717