title: Engineering new protein-protein interactions on the β-propeller fold by yeast cell surface display.
abstract: REINVENTING THE WHEEL: The β-propeller domain folds like a wheel to provide key protein-protein interactions in the cell. Here we used high-throughput yeast sorting to "invent" β-propellers of new binding specificities with cellular targets.
authors: Department of Chemistry, University of Chicago, 929 E57th Street, Chicago, IL 60637, USA.
authors: Keya
authors: K
authors: Zhang
authors: Heng
authors: H
authors: Li
authors: Karan
authors: K
authors: Bhuripanyo
authors: Bo
authors: B
authors: Zhao
authors: Tiffany F
authors: TF
authors: Chen
authors: Ning
authors: N
authors: Zheng
authors: Jun
authors: J
authors: Yin
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D000818:Animals; D061505:Cell Surface Display Techniques / Q000379:methods*; D003598:Cytoskeletal Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D000072019:Kelch-Like ECH-Associated Protein 1; D051379:Mice; D008958:Models, Molecular; D009154:Mutation; D017510:Protein Folding; D060066:Protein Interaction Maps; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D015003:Yeasts / Q000235:genetics* / Q000378:metabolism
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D003598:Cytoskeletal Proteins; C117301:Keap1 protein, mouse; D000072019:Kelch-Like ECH-Associated Protein 1
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