title: Pre-pregnancy body mass index moderates the effect of maternal depressive symptoms on small-for-gestational-age infants.
abstract: OBJECTIVE
  We aimed to investigate whether the negative effects of maternal depressive symptoms on Small for gestational age (SGA) was moderated by pre-pregnancy body mass index.
  
  
  METHODS
  A total of 9,851 women provided self-reported height and pre-pregnancy weight at their first prenatal visit. Pre-pregnancy BMI was categorized according to the BMI cut point ranges for Chinese adults. Depression during pregnancy was assessed by using standardized questionnaires. Demographic characteristics and birth outcomes, including gestational age at birth and birth weight, were collected through the interviews and case history. Multiple regression analysis was used to estimate the relationship between depressive symptoms and SGA among various pre-pregnancy BMI groups.
  
  
  RESULTS
  The relationship between depressive symptoms and SGA was inconsistent among three pre-pregnancy BMI groups. The incidence of SGA was positively related with depressive symptoms only among women with pre-pregnancy underweight [odds ratio (OR) 1.89, 95 % confidence interval (CI) 1.12-3.21].
  
  
  CONCLUSIONS
  The negative effect of depressive symptoms during pregnancy on SGA depends on pre-pregnancy BMI.
authors: Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, 81st Meishan Road, Hefei 230032, China.
authors: Ling
authors: L
authors: Tang
authors: Peng
authors: P
authors: Zhu
authors: Jia-Hu
authors: JH
authors: Hao
authors: Kun
authors: K
authors: Huang
authors: Shao-Jun
authors: SJ
authors: Xu
authors: Hong
authors: H
authors: Wang
authors: Lei
authors: L
authors: Wang
authors: Fang-Biao
authors: FB
authors: Tao
mesh_terms: D000328:Adult; D001724:Birth Weight; D015992:Body Mass Index; D016009:Chi-Square Distribution; D016001:Confidence Intervals; D003863:Depression / Q000453:epidemiology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D016017:Odds Ratio; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology* / Q000523:psychology; D012044:Regression Analysis; D013851:Thinness / Q000453:epidemiology; D055815:Young Adult