title: A comparison of open surgery and endovascular intervention for hepatic artery complications after pediatric liver transplantation.
abstract: There are currently 2 major therapeutic options for the treatment of hepatic artery complications: endovascular intervention and open surgery. We herein report a retrospective analysis of 14 pediatric patients with hepatic artery complications after pediatric living donor liver transplantation (LDLT) at our institution. We divided them into an open surgery group and an endovascular intervention group based on their primary treatment, and compared the results and outcomes. We then evaluated which procedure is more effective and less invasive. In the open surgery group, recurrent stenosis or spasm of the hepatic artery occurred in 3 of the 8 patients (37.5%). In the endovascular intervention group, 5 of the 6 patients were technically successfully treated by only endovascular treatment. Of the 5 successfully treated patients, 3 developed recurrent stenosis (60%). There were significant differences in the mean length of the operation for the first treatment of hepatic artery complications (open surgery, 428 minutes vs endovascular intervention, 160 minutes; P = .01) and in the mean value of the posttreatment aspartate aminotransferase (AST)/alanine aminotransferase (ALT) (open surgery > endovascular intervention; P = .04/.05). Although endovascular intervention needs to be examined in further studies to reduce the rate of relapse, it is a less invasive method for the patient and graft than open surgery.
authors: Department of Transplant Surgery, Jichi Medical University, Shimotsuke, Tochigi, Japan. wakiya@jichi.ac.jp
authors: T
authors: T
authors: Wakiya
authors: Y
authors: Y
authors: Sanada
authors: K
authors: K
authors: Mizuta
authors: T
authors: T
authors: Urahashi
authors: Y
authors: Y
authors: Ihara
authors: N
authors: N
authors: Yamada
authors: N
authors: N
authors: Okada
authors: S
authors: S
authors: Egami
authors: M
authors: M
authors: Nakata
authors: K
authors: K
authors: Hakamada
authors: Y
authors: Y
authors: Yasuda
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003251:Constriction, Pathologic / Q000209:etiology*; D057510:Endovascular Procedures / Q000379:methods*; D005260:Female; D006499:Hepatic Artery / Q000473:pathology*; D006801:Humans; D007223:Infant; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D011183:Postoperative Complications; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome; D014652:Vascular Diseases / Q000209:etiology*
chemical_list: D000925:Anticoagulants