title: Diabetes mellitus and cancer in Werner syndrome.
abstract: Onishi et al. recently reported here an association of diabetes mellitus (DM) with neoplasm type in newly identified patients with Werner syndrome (WS), an autosomal recessive cancer predisposition syndrome with features of premature aging that include a high risk of DM (Onishi et al. in Acta Diabetol 49(Suppl 1):259-260, 2012; Epstein et al. in Medicine 45:177-121, 1966). In contrast, we did not detect an association between DM and neoplasm type in an independent WS cohort we assembled to determine the histopathologic spectrum and type-specific risk of neoplasia in WS.
authors: Department of Epidemiology, University of Washington, Seattle, WA, 98195-7705, USA.
authors: Julia M
authors: JM
authors: Lauper
authors: Raymond J
authors: RJ
authors: Monnat
mesh_terms: D048909:Diabetes Complications / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000209:etiology*; D014898:Werner Syndrome / Q000150:complications*
references: Mol Carcinog. 2012 Jan;51(1):64-74
references: 22162232
references: Medicine (Baltimore). 1966 May;45(3):177-221
references: 5327241
references: Diabetes Care. 2010 Jul;33(7):1674-85
references: 20587728
references: Neurosurgery. 1980 Nov;7(5):517-20
references: 7003435
references: Acta Diabetol Lat. 1984 Apr-Jun;21(2):193-7
references: 6382894
references: Acta Diabetol. 2012 Dec;49 Suppl 1:S259-60
references: 22872450