title: Asymmetric Michael reactions catalyzed by a highly efficient and recyclable quaternary ammonium ionic liquid-supported organocatalyst in aqueous media.
abstract: A novel ionic liquid-support organocatalyst, which contains the quaternary ammonium ion moiety, was recently developed and successfully applied to the asymmetric Michael reaction in the presence of a newly developed ionic liquid-supported (ILS) benzoic acid as co-catalyst. For the reactions studied, in which various aldehydes and nitroolefins were examined, excellent diastereo- and enantioselectivities were obtained with low catalyst loading. Also, the catalyst could be recycled for ten times without significant loss of enantioselectivity.
authors: Department of Chemistry, Texas A&M University-Commerce, Commerce, TX 75429-3001, USA.
authors: Subrata K
authors: SK
authors: Ghosh
authors: Yupu
authors: Y
authors: Qiao
authors: Bukuo
authors: B
authors: Ni
authors: Allan D
authors: AD
authors: Headley
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D000475:Alkenes / Q000737:chemistry; D019817:Benzoic Acid / Q000737:chemistry; D002384:Catalysis; D052578:Ionic Liquids / Q000737:chemistry*; D015394:Molecular Structure; D009574:Nitro Compounds / Q000138:chemical synthesis / Q000737:chemistry; D000644:Quaternary Ammonium Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D014867:Water / Q000737:chemistry
chemical_list: D000447:Aldehydes; D000475:Alkenes; D052578:Ionic Liquids; D009574:Nitro Compounds; D000644:Quaternary Ammonium Compounds; D014867:Water; D019817:Benzoic Acid