title: [Development of a method for the assessment of melamine in urines by GC-MS/MS. An attempt to define a reference value].
abstract: Melamine is used in the synthesis of resins used for the manufacture of laminates, plastics and coatings, including materials in contact with food such as crockery. A method for the assessment of melamine by GC-MSMS in urine samples was developed and tested in 100 non-occupationally exposed subjects: 63 females (14-66) and 37 males (15-65). The LOD and LOQ were 4 microg/l and 13.4 microg/l respectively. Results showed traces of melamine in the urines of 21% of subjects monitored (10-29.7 microg/l). Presence of melamine and time since last meal at sampling were inversely related (p = 0.021). In addition a significant correlation (p = 0.00) between the presence of the substance in urines and the use of melamine dishes was shown.
authors: Dipartimento di Traumatologia, Ortopedia e Medicina del Lavoro, Università di Torino, Via Zuretti 29, 10126 Torino, Italy.
authors: C
authors: C
authors: Romano
authors: E
authors: E
authors: Marchetti
authors: A
authors: A
authors: Genova
authors: E
authors: E
authors: Buglione
authors: V
authors: V
authors: Passini
authors: M C
authors: MC
authors: Valsania
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D014227:Triazines / Q000652:urine*; D055815:Young Adult
chemical_list: D014227:Triazines; C011907:melamine