title: Subfoveal serous retinal detachment associated with extramacular branch retinal vein occlusion.
abstract: OBJECTIVE
  To study the pathophysiology of subfoveal serous retinal detachment (SRD) observed in eyes with extramacular branch retinal vein occlusion (BRVO).
  
  
  METHODS
  We retrospectively reviewed the medical records of nine patients (nine eyes) with extramacular BRVO with macular complications that were examined using optical coherence tomography (OCT).
  
  
  RESULTS
  Extramacular BRVO was observed in the inferior area in three eyes, in the superior area in five eyes, and in the nasal area in one eye. Visual acuity was moderately disturbed (median, 0.6; range, 0.2-0.9, measured using the Landolt chart). One eye showed extensive SRD that was connected to the area affected by BRVO through the subretinal space. In eight of the eyes, focal SRD was observed beneath the fovea without subretinal connections to the area affected by BRVO. However, all these eyes showed marked retinal swelling in the outer retina, particularly in the outer plexiform layer. In two of the eyes, detailed OCT examinations showed a small break on the external surface of the retina connecting the swollen outer retina with the underlying SRD. All eyes showed hyperreflective foci in the outer retina, most frequently along the inner boundary of the outer plexiform layer and external limiting membrane.
  
  
  CONCLUSIONS
  Extramacular BRVO is often accompanied by focal SRD beneath the fovea. Leakage from the retinal capillaries affected by BRVO travelled via the outer plexiform layer and caused SRD under the fovea.
authors: Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors: Toru
authors: T
authors: Ota
authors: Akitaka
authors: A
authors: Tsujikawa
authors: Tomoaki
authors: T
authors: Murakami
authors: Ken
authors: K
authors: Ogino
authors: Yuki
authors: Y
authors: Muraoka
authors: Kyoko
authors: K
authors: Kumagai
authors: Yumiko
authors: Y
authors: Akagi-Kurashige
authors: Kazuaki
authors: K
authors: Miyamoto
authors: Nagahisa
authors: N
authors: Yoshimura
keywords: branch retinal vein occlusion; extramacular; macular edema; optical coherence tomography; retinal detachment
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