title: Pulp revascularization after root canal decontamination with calcium hydroxide and 2% chlorhexidine gel.
abstract: BACKGROUND
  Pulp revascularization may be considered a promising alternative for necrotic immature teeth. Many studies have accomplished passive decontamination associated with an antibiotic paste. To date, there is no report evaluating calcium hydroxide associated with 2% chlorhexidine gel for revascularization therapy. The aim of this case report was to describe a new proposal for pulp revascularization with mechanical decontamination and intracanal medication composed of calcium hydroxide and 2% chlorhexidine gel.
  
  
  METHODS
  The patient, a 9-year-old girl, suffered an intrusion associated with pulp exposure caused by an enamel-dentin fracture in her maxillary left central incisor. After diagnosis, treatment consisted of revascularization therapy with gentle manual instrumentation of the cervical and medium thirds of the root in addition to intracanal medication with calcium hydroxide and 2% chlorhexidine gel for 21 days. In the second session, a blood clot was stimulated up to the cervical third of the root canal. Mineral trioxide aggregate (MTA; Angelus, Londrina, Paraná, Brazil) was used for cervical sealing of the canal. Coronal sealing was performed with temporary filling material and composite resin.
  
  
  RESULTS
  During the follow-up period, the root canal space showed a progressive decrease in width, mineralized tissue deposition on root canal walls, and apical closure. A cone-beam computed tomography scan taken at the 2-year follow-up confirmed these findings and did not show complete root canal calcification.
  
  
  CONCLUSIONS
  This new proposal for revascularization therapy with 2% chlorhexidine gel may be used for the treatment of necrotic immature root canals.
authors: Department of Restorative Dentistry, Endodontics Area, State University of Campinas-UNICAMP, Piracicaba, São Paulo, Brazil. ajsoares.endo@uol.com.br
authors: Adriana de Jesus
authors: Ade J
authors: Soares
authors: Fernanda Freitas
authors: FF
authors: Lins
authors: Juliana Yuri
authors: JY
authors: Nagata
authors: Brenda Paula Figueiredo de Almeida
authors: BP
authors: Gomes
authors: Alexandre Augusto
authors: AA
authors: Zaia
authors: Caio Cezar Randi
authors: CC
authors: Ferraz
authors: José Flávio Affonso
authors: JF
authors: de Almeida
authors: Francisco José
authors: FJ
authors: de Souza-Filho
mesh_terms: D017607:Aluminum Compounds; D056624:Apexification; D001777:Blood Coagulation; D017610:Calcium Compounds; D002126:Calcium Hydroxide / Q000627:therapeutic use*; D002648:Child; D002710:Chlorhexidine / Q000627:therapeutic use*; D054893:Cone-Beam Computed Tomography; D003782:Dental Pulp / Q000098:blood supply*; D003786:Dental Pulp Cavity / Q000000981:diagnostic imaging; D003789:Dental Pulp Exposure / Q000628:therapy; D003790:Dental Pulp Necrosis / Q000628:therapy; D004338:Drug Combinations; D005260:Female; D006801:Humans; D018919:Neovascularization, Physiologic; D010087:Oxides; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants / Q000627:therapeutic use*; D012390:Root Canal Therapy / Q000379:methods*; D017640:Silicates; D019227:Tooth Apex / Q000254:growth & development; D014084:Tooth Avulsion / Q000628:therapy; D014082:Tooth Fractures / Q000000981:diagnostic imaging
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D012388:Root Canal Irrigants; D017640:Silicates; C086631:mineral trioxide aggregate; D002126:Calcium Hydroxide; D002710:Chlorhexidine