title: Localization and evolution of septins in algae.
abstract: Septins are a group of GTP-binding proteins that are multi-functional, with a well-known role in cytokinesis in animals and fungi. Although the functions of septins have been thoroughly studied in opisthokonts (fungi and animals), the function and evolution of plant/algal septins are not as well characterized. Here we describe septin localization and expression in the green algae Nannochloris bacillaris and Marvania geminata. The present data suggest that septins localize at the division site when cytokinesis occurs. In addition, we show that septin homologs may be found only in green algae, but not in other major plant lineages, such as land plants, red algae and glaucophytes. We also found other septin homolog-possessing organisms among the diatoms, Rhizaria and cryptomonad/haptophyte lineages. Our study reveals the potential role of algal septins in cytokinesis and/or cell elongation, and confirms that septin genes appear to have been lost in the Plantae lineage, except in some green algae.
authors: Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8562, Japan.
authors: Tomokazu
authors: T
authors: Yamazaki
authors: Satomi
authors: S
authors: Owari
authors: Shuhei
authors: S
authors: Ota
authors: Nobuko
authors: N
authors: Sumiya
authors: Maki
authors: M
authors: Yamamoto
authors: Koichi
authors: K
authors: Watanabe
authors: Tamotsu
authors: T
authors: Nagumo
authors: Shinichi
authors: S
authors: Miyamura
authors: Shigeyuki
authors: S
authors: Kawano
mesh_terms: D020418:Algal Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D000595:Amino Acid Sequence; D005075:Biological Evolution; D002455:Cell Division; D000460:Chlorophyta / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D048749:Cytokinesis; D019084:Fluorescent Antibody Technique, Indirect; D019204:GTP-Binding Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism; D008855:Microscopy, Electron, Scanning; D008856:Microscopy, Fluorescence; D008954:Models, Biological; D008969:Molecular Sequence Data; D010671:Phenylurea Compounds / Q000494:pharmacology; D010802:Phylogeny; D011485:Protein Binding; D017434:Protein Structure, Tertiary; D011725:Pyridines / Q000494:pharmacology; D058112:Septins / Q000037:antagonists & inhibitors / Q000235:genetics* / Q000378:metabolism
chemical_list: D020418:Algal Proteins; D010671:Phenylurea Compounds; D011725:Pyridines; D019204:GTP-Binding Proteins; D058112:Septins; C116093:N-(2-chloro-4-pyridyl)-N'-phenylurea