title: Myocarditis in 9- and 11-day-old broiler breeder chicks associated with a reovirus infection.
abstract: Nine- and 11-day-old male broiler breeder chicks from a flock with excessively high mortality were found to have ascites, fibrotic and necrotic livers, and round, thin-walled hearts. Virus isolation on liver homogenates and sequencing of PCR products of the isolate identified a reovirus whose sequence varied from sequences of other published reoviruses. Histopathology supported a diagnosis of reovirus-associated myocarditis and myocardial necrosis. This virus was possibly transmitted vertically from the primary breeder flock.
authors: Georgia Poultry Laboratory Network, P.O. Box 20, Oakwood, GA 30566, USA. jdavis@gapoultrylab.org
authors: James F
authors: JF
authors: Davis
authors: Arun
authors: A
authors: Kulkarni
authors: Oscar
authors: O
authors: Fletcher
mesh_terms: D000818:Animals; D002645:Chickens; D017809:Fatal Outcome; D008099:Liver / Q000473:pathology*; D008297:Male; D008969:Molecular Sequence Data; D009205:Myocarditis / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D009206:Myocardium / Q000473:pathology*; D030101:Orthoreovirus, Avian / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D011201:Poultry Diseases / Q000473:pathology* / Q000821:virology; D012088:Reoviridae Infections / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D020133:Reverse Transcriptase Polymerase Chain Reaction / Q000662:veterinary; D017422:Sequence Analysis, DNA / Q000662:veterinary; D054334:Viral Regulatory and Accessory Proteins / Q000235:genetics
chemical_list: D054334:Viral Regulatory and Accessory Proteins; C031657:sigma NS protein, Reovirus