title: Ovum transmigration after salpingectomy for ectopic pregnancy.
abstract: OBJECTIVE
  What proportion of pregnancies are a result of ovum transmigration after salpingectomy for ectopic pregnancy?
  
  
  CONCLUSIONS
  Approximately one-third of spontaneously conceived pregnancies are a result of pick-up of the ovum from the ovary contralateral to the remaining tube in women with a history of salpingectomy.
  
  
  BACKGROUND
  The corpus luteum has been found contralateral to tubal ectopic pregnancies in 32% of reported cases. The rate of contralateral ovum pick-up in intrauterine pregnancies is not known.
  
  
  METHODS
  We conducted a retrospective cohort study of clinical and ultrasound records collected over a 12-year period 1999-2010. Ten per cent of cases identified were excluded from the final analysis due to incomplete data or bilateral corpora lutea.
  
  
  METHODS
  Included were 842 pregnancies in 707 women with a history of unilateral salpingectomy for ectopic pregnancy and subsequent spontaneous pregnancy. The study was set in the Early Pregnancy Unit of a large UK inner city teaching hospital. The outcome measure was the side of the corpus luteum in relation to the side of the remaining tube.
  
  
  RESULTS
  The corpus luteum was located in the ovary contralateral to the remaining tube in 266/842 pregnancies (31.6%; 95% CI 28.5-34.8%). There was no significant difference in this proportion between intrauterine and ectopic pregnancies [246/769 (32.0%) versus 21/73 (28.8%), P = 0.60].
  
  
  CONCLUSIONS
  This was a retrospective study and so did not address the conception rate according to the laterality of ovulation.
  
  
  CONCLUSIONS
  Our findings were very similar to the frequency of ectopic pregnancies found contralateral to the corpus luteum described in previous studies. Ovum pick-up from the cul-de-sac probably occurs reasonably frequently and is unlikely to have a causative role in the pathogenesis of ectopic pregnancy. It is not known how often this phenomenon occurs in women with intact Fallopian tubes.
  
  
  BACKGROUND
  No specific funding was obtained. The authors have no conflicts of interest to declare.
authors: Early Pregnancy and Gynaecology Assessment Unit, Suite 8, Golden Jubilee Wing, King's College Hospital, Denmark Hill, London SE5 9RS, UK. jackie.ross1@nhs.net
authors: Jackie A
authors: JA
authors: Ross
authors: Amelia Z
authors: AZ
authors: Davison
authors: Yasmin
authors: Y
authors: Sana
authors: Adjoa
authors: A
authors: Appiah
authors: Jemma
authors: J
authors: Johns
authors: Christopher T
authors: CT
authors: Lee
mesh_terms: D000328:Adult; D002465:Cell Movement; D003338:Corpus Luteum / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D010063:Ovum / Q000166:cytology* / Q000000981:diagnostic imaging; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000601:surgery*; D012189:Retrospective Studies; D058994:Salpingectomy; D016216:Ultrasonography, Prenatal