title: Survival rates in patients with diabetes on peritoneal dialysis in China.
abstract: OBJECTIVE
  To compare overall survival and technical survival in diabetic mellitus (DM) and non-DM (N-DM) Chinese patients undergoing peritoneal dialysis (PD), and to discuss the factors involved.
  
  
  METHODS
  Clinical data were analyzed for all adult patients (age >18 years) with chronic renal failure who had commenced PD between 2006 and 2010 in a single Chinese center.
  
  
  RESULTS
  Compared to the N-DM group, the DM group was older (64.5 ± 11.9 years vs. 59.2 ± 15.2 years, p = 0.023), with a higher body mass index (BMI) (25.2 ± 3.5 kg/m(2) vs. 23.2 ± 3.5 kg/m(2), p = 0.001), a higher estimated glomerular filtration rate (eGFR) (10.4 ± 4.7 mL/min/1.73 m(2) vs. 6.9 ± 2.9 mL/min/1.73 m(2), p = 0.000), and lower intact parathyroid levels (81.35 pg/mL vs. 186.3 pg/mL, p = 0.003). During the average 23.8-month follow-up period, the 1-, 2-, and 3-year survival rates of the DM group were 95.8%, 69.2%, and 60%, respectively. The 1-, 2-, and 3-year survival rates of the N-DM group were 87.2%, 76.5%, and 66.7%, respectively. There was no significant difference in survival between the groups. The 1-, 2-, and 3-year technical survival rates of the DM group were 93.8%, 69.2% and 60%, respectively. The 1-, 2-, and 3-year technical survival rates of the N-DM group were 84.6%, 72.5% and 63.3%, respectively. There was no significant difference in technical survival between the groups. Within the DM group, the only factor predictive for both overall survival (p = 0.015) and technical survival (p = 0.009) was the initial BMI, and both survival outcomes in DM patients with a BMI greater than 24 were higher than those observed with a BMI less than 24.
  
  
  CONCLUSIONS
  In the first 3 years of PD, DM and N-DM patients have similar survival rates. Chinese DM patients with a higher BMI undergoing PD appear to have higher survival rates than those with a lower BMI.
authors: Peking University People's Hospital, Beijing, China.
authors: Bei
authors: B
authors: Wu
authors: Mei
authors: M
authors: Wang
authors: Huiping
authors: H
authors: Zhao
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000453:epidemiology; D016022:Case-Control Studies; D002423:Cause of Death; D016009:Chi-Square Distribution; D002681:China; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D003928:Diabetic Nephropathies / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000379:methods / Q000401:mortality*; D011379:Prognosis; D016016:Proportional Hazards Models; D018570:Risk Assessment; D012720:Severity of Illness Index; D012737:Sex Factors; D018709:Statistics, Nonparametric; D016019:Survival Analysis