title: Quantification of viral loads lower than 50 copies per milliliter by use of the Cobas AmpliPrep/Cobas TaqMan HIV-1 test, version 2.0, can predict the likelihood of subsequent virological rebound to >50 copies per milliliter.
abstract: After 1 year of follow-up, patients on HAART with a baseline viral load (VL) of <20 copies/ml showed significantly lower odds of virological rebound to two consecutive VLs of >50 copies/ml than those with baseline VLs of 20 to 39 and 40 to 49 (P < 0.001). The time to virological rebound was also significantly shorter (P < 0.001) for the groups with baseline VLs of 20 to 39 and 40 to 49.
authors: Microbiology Service, Hospital Universitario San Cecilio, Granada, Spain.
authors: Marta
authors: M
authors: Álvarez Estévez
authors: Natalia
authors: N
authors: Chueca Porcuna
authors: Vicente
authors: V
authors: Guillot Suay
authors: Alejandro
authors: A
authors: Peña Monge
authors: Fernando
authors: F
authors: García García
authors: Leopoldo
authors: L
authors: Muñoz Medina
authors: David
authors: D
authors: Vinuesa García
authors: Jorge
authors: J
authors: Parra Ruiz
authors: Jose
authors: J
authors: Hernández-Quero
authors: Federico
authors: F
authors: García García
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000821:virology*; D015497:HIV-1 / Q000235:genetics / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012367:RNA, Viral / Q000032:analysis; D012008:Recurrence; D019562:Viral Load; D014766:Viremia
chemical_list: D012367:RNA, Viral
references: J Clin Microbiol. 2011 Jan;49(1):118-24
references: 21084515
references: HIV Clin Trials. 2008 Jul-Aug;9(4):283-6
references: 18753122
references: Open Virol J. 2012;6:135-43
references: 23264839
references: J Acquir Immune Defic Syndr. 2012 Aug 15;60(5):473-82
references: 22481602
references: Clin Infect Dis. 2012 Mar 1;54(5):724-32
references: 22238167
references: Enferm Infecc Microbiol Clin. 2009 Feb;27(2):75-80
references: 19254638
references: J Clin Microbiol. 2011 Jan;49(1):377-9
references: 20980564
references: J Clin Virol. 2011 Sep;52(1):17-22
references: 21764631
references: Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3879-84
references: 18332425
references: PLoS One. 2012;7(11):e50065
references: 23166820
references: J Clin Microbiol. 2011 Jan;49(1):292-7
references: 21068276
references: AIDS. 2010 Oct 23;24(16):2535-9
references: 20651585
references: J Antimicrob Chemother. 2012 Sep;67(9):2231-5
references: 22643190