title: Computational simulation-based vessel interposition reconstruction technique for portal vein hypoplasia in pediatric liver transplantation.
abstract: BACKGROUND
  To enhance the technical feasibility of portal vein (PV) interposition grafting for pediatric PV hypoplasia, we performed a computational simulation to establish a customized surgical technique allowing a secure anastomosis of an iliac vein graft to a severely hypoplastic PV stump.
  
  
  METHODS
  Based on the literature and on our own experience with reconstruction of PV hypoplasia, we devised three types of recipient PV stump preparations and three types of interposition vein grafts, yielding five technically feasible combinations.
  
  
  RESULTS
  The computational simulation model for PV reconstruction using an interposition vein graft revealed the most feasible combination to be a sequential inverted-T incision to the confluence of the superior mesenteric vein and splenic vein with a longitudinal slit in the transverse vein graft end, the technical feasibility was validated by an artificial suture model. This reconstruction was clinically applied to treat a 7.2-kg 10-month-old female patient with biliary atresia and a severely hypoplastic PV. The PV reconstruction was successful; the patient recovered uneventfully.
  
  
  CONCLUSIONS
  We have presented a simplified surgical technique for PV interposition that is applicable to pediatric PV hypoplasia, which also appears to be a feasible option for pediatric liver transplantation.
authors: Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. shwang@amc.seoul.kr
authors: S
authors: S
authors: Hwang
authors: D Y
authors: DY
authors: Kim
authors: C S
authors: CS
authors: Ahn
authors: D B
authors: DB
authors: Moon
authors: K M
authors: KM
authors: Kim
authors: G C
authors: GC
authors: Park
authors: J M
authors: JM
authors: Namgoong
authors: S W
authors: SW
authors: Jung
authors: S Y
authors: SY
authors: Yoon
authors: Y H
authors: YH
authors: Park
authors: S G
authors: SG
authors: Lee
mesh_terms: D000328:Adult; D000714:Anastomosis, Surgical; D003198:Computer Simulation; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007223:Infant; D017093:Liver Failure / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D011169:Portal Vein / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014656:Vascular Surgical Procedures / Q000379:methods*