title: Positive correlation between serum taurine and adiponectin levels in high-fat diet-induced obesity rats.
abstract: The purpose of this study was to investigate the relationship between serum taurine level and serum adiponectin or leptin levels in high-fat diet-induced obesity rats. Five-week-old male Sprague-Dawley rats were randomly divided into three groups for a period of 8 weeks (normal diet, N group; high-fat diet, HF group; high-fat diet + taurine, HFT group). Taurine was supplemented by dissolving in feed water (3% w/v), and the same amount of distilled water was orally administrated to N and HF groups. In serum, adiponectin level was higher in HFT group compared to HF group. The serum taurine level was negatively correlated with serum total cholesterol (TC) level and positively correlated with serum adiponectin level. These results suggest that dietary taurine supplementation has beneficial effects on total cholesterol and adiponectin levels in high-fat diet-induced obesity rats.
authors: Deptartment of Food and Nutrition, Inha University, Incheon, South Korea.
authors: Jeong Soon
authors: JS
authors: You
authors: Xu
authors: X
authors: Zhao
authors: Sung Hoon
authors: SH
authors: Kim
authors: Kyung Ja
authors: KJ
authors: Chang
mesh_terms: D052242:Adiponectin / Q000097:blood*; D000273:Adipose Tissue / Q000033:anatomy & histology; D000818:Animals; D001835:Body Weight; D059305:Diet, High-Fat / Q000009:adverse effects*; D020738:Leptin / Q000097:blood; D008055:Lipids / Q000097:blood; D008297:Male; D009765:Obesity / Q000097:blood*; D009929:Organ Size; D051381:Rats; D017207:Rats, Sprague-Dawley; D013654:Taurine / Q000097:blood*
chemical_list: D052242:Adiponectin; D020738:Leptin; D008055:Lipids; D013654:Taurine