title: Human dietary exposure to polycyclic aromatic hydrocarbons: results of the second French Total Diet Study.
abstract: In the frame of the second French Total Diet Study (TDS), the 15+1 EU priority polycyclic aromatics hydrocarbons (PAHs) were analyzed in 725 foodstuffs habitually consumed by the French population, using gas chromatography coupled to tandem mass spectrometry, after pressurized liquid extraction and purification on PS-DVB stationary phase. The highest PAH concentrations recovered in foodstuffs corresponded to the following contributors: chrysene (25.7%), benzo[b]fluoranthene (15.0%) and benz[a]anthracene (9.0%) whereas the lowest concentrations were those of dibenz[a,h]anthracene, 5 methylchrysene and dibenzo[a,h]pyrene (below 2.0%). By food groups, the current highest levels of total PAH were detected in mollusks and crustaceans, followed by the different oil based products. To estimate French population's exposure, contamination data were combined with national individual food consumption data. Mean daily exposure to the sum of benzo[a]pyrene, benz[a]anthracene, chrysene and benzo[b]fluoranthene (PAH4) was estimated to be 1.48 ng/kg bw/day in adults and 2.26 ng/kg bw/day in children. The main contributors to PAH exposure for adults are fats, bread and dried bread products followed by crustaceans and mollusks. The margin of exposure (MOE) approach indicates that exposure to PAHs through food is not a major health problem for French consumers.
authors: LUNAM Université, ONIRIS, Ecole Nationale Vétérinaire, Agroalimentaire et de l'Alimentation Nantes-Atlantique, Laboratoire d'Etude des Résidus et Contaminants dans les Aliments (LABERCA), Atlanpôle-La Chantrerie, BP 50707, Nantes F-44307, France. laberca@oniris-nantes.fr
authors: Bruno
authors: B
authors: Veyrand
authors: Véronique
authors: V
authors: Sirot
authors: Sophie
authors: S
authors: Durand
authors: Charles
authors: C
authors: Pollono
authors: Philippe
authors: P
authors: Marchand
authors: Gaud
authors: G
authors: Dervilly-Pinel
authors: Alexandra
authors: A
authors: Tard
authors: Jean-Charles
authors: JC
authors: Leblanc
authors: Bruno
authors: B
authors: Le Bizec
mesh_terms: D000328:Adult; D002648:Child; D004032:Diet / Q000706:statistics & numerical data*; D004781:Environmental Exposure / Q000706:statistics & numerical data*; D004785:Environmental Pollutants / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis* / Q000706:statistics & numerical data; D005602:France; D006306:Health Surveys; D006801:Humans; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis*
chemical_list: D004785:Environmental Pollutants; D011084:Polycyclic Aromatic Hydrocarbons