title: Failure-free survival of the Durata defibrillator lead.
abstract: OBJECTIVE
  Given design similarities and a common manufacturer, there have been suspicions regarding the Durata™ defibrillator (ICD) lead, in the aftermath of the Riata™ class I recall. We therefore examined the failure-free survival rates of the Durata™ compared with the Riata™ and Sprint Quattro™ ICD leads.
  
  
  RESULTS
  All patients (n = 2475) implanted with a Durata (n = 828), Riata [n = 627; 8 Fr. (n = 472) and 7 Fr. (n = 155)], or Sprint Quattro (n = 1020) leads at our institution were included and Kaplan-Meier failure-free survival curves were constructed for all leads. Lead failure was defined as electrical malfunction resulting in lead replacement, excluding dislodgements or perforations. Annual electrical failure rates were 0.3%, 1.7, and 0.3% for the Durata, Riata, and Sprint Quattro leads, respectively (P < 0.0001 for the comparison of Durata to Riata and P = 0.1.0 for the comparison of Durata to Sprint Quattro). The failure-free survival of the Durata lead was significantly better than that of the Riata lead (P < 0.0001) and similar to that of the Sprint Quattro (P = 0.94). The 7 Fr. Riata ST lead had better survival compared with the 8 Fr. Riata lead (P = 0.050) and comparable survival with the Durata lead (P = 0.12).
  
  
  CONCLUSIONS
  The Durata lead failure-free survival is significantly better than the 8 Fr. Riata, albeit at a shorter follow-up time. Riata and comparable with that of the 7 Fr. Riata ST and the Sprint Quattro ICD leads. These data provide an insight into the mechanism of electrical failure of Riata leads and have implications for patient management.
authors: Heart and Vascular Institute, University of Pittsburgh Medical Center, 200 Lothrop Street, UPMC Presbyterian, Pittsburgh, PA 15213-2582, USA.
authors: Jeffrey
authors: J
authors: Liu
authors: Divyang
authors: D
authors: Patel
authors: Rohit
authors: R
authors: Rattan
authors: Genevieve
authors: G
authors: Brumberg
authors: Aditya
authors: A
authors: Saini
authors: Nishit
authors: N
authors: Vaghasia
authors: Raveen
authors: R
authors: Bazaz
authors: Evan
authors: E
authors: Adelstein
authors: Sandeep
authors: S
authors: Jain
authors: Samir
authors: S
authors: Saba
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D017147:Defibrillators, Implantable; D020878:Device Removal; D018572:Disease-Free Survival; D004554:Electric Countershock / Q000009:adverse effects / Q000295:instrumentation*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D010414:Pennsylvania; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome
keywords: Defibrillator lead; Durata; Failure; Riata