title: Recruitment and retention of under-represented groups with health disparities into clinical trials: a formative approach.
abstract: We evaluated the perceived success of recruitment and retention protocols for Native Hawaiian/Pacific Islander/Filipino populations. These three groups were found to have a significantly higher incidence of health disparities than the general population. Training applications of selected vignettes were also generated. Focus groups and questionnaires were used to achieve the objective: identification of themes related to facilitators and deterrents to participation in clinical trials in these populations. This mixed methods approach evaluated promotional materials preferred. Responses to animated videos and vignettes with actors regarding clinical research participation were analyzed. Participants included adults of Hawaiian/Pacific Islander or Filipino ethnicity. Analysis included grounded theory methods, such as constant comparative techniques. The results revealed that attention to the following categories is essential: culturally sensitive knowledge, attitudes, and beliefs related to individuals, families and communities. These themes are recommended as the structure for future interventions to improve participation and retention within these groups.
authors: Department of Complementary and Alternative Medicine, John A. Burns School of Medicine, 651 Ilalo St., Medical Education Building, Honolulu, HI, 96813, USA, harrigan@hawaii.edu.
authors: Rosanne
authors: R
authors: Harrigan
authors: Michael H
authors: MH
authors: Perez
authors: Steven
authors: S
authors: Beaudry
authors: Crystal
authors: C
authors: Johnson
authors: Payel
authors: P
authors: Sil
authors: Kau'ionālani
authors: K
authors: Mead
authors: Noelani
authors: N
authors: Apau-Ludlum
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002986:Clinical Trials as Topic / Q000379:methods*; D054521:Cultural Competency; D003469:Culture; D005260:Female; D017144:Focus Groups; D066296:Grounded Theory; D057220:Health Literacy; D054624:Health Status Disparities; D006801:Humans; D008297:Male; D008875:Middle Aged; D044468:Native Hawaiian or Pacific Islander / Q000208:ethnology; D010352:Patient Dropouts; D018579:Patient Selection; D010679:Philippines / Q000208:ethnology; D055815:Young Adult
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