title: Immune- and wound-dependent differential gene expression in an ancient insect.
abstract: Two of the main functions of the immune system are to control infections and to contribute to wound closure. Here we present the results of an RNAseq study of immune- and wound-response gene expression in the damselfly Coenagrion puella, a representative of the odonates, the oldest taxon of winged insects. De novo assembly of RNAseq data revealed a rich repertoire of canonical immune pathways, as known from model insects, including recognition, transduction and effector gene expression. A shared set of immune and wound repair genes were differentially expressed in both wounded and immune-challenged larvae. Moreover 3-fold more immune genes were induced only in the immune-challenged treatment. This is consistent with the notion that the immune-system reads a balance of signals related to wounding and infection and that the response is tailored accordingly.
authors: Evolutionary Biology, Institute for Biology, Free University Berlin, Königin Luise Strasse 1-3, 14195 Berlin, Germany. paul.johnston@fu-berlin.de
authors: Paul R
authors: PR
authors: Johnston
authors: Jens
authors: J
authors: Rolff
mesh_terms: D000818:Animals; D004926:Escherichia coli / Q000276:immunology; D005786:Gene Expression Regulation / Q000276:immunology*; D054884:Host-Pathogen Interactions; D007107:Immune System; D007113:Immunity, Innate / Q000235:genetics; D019476:Insect Proteins / Q000235:genetics / Q000378:metabolism*; D007814:Larva / Q000276:immunology / Q000378:metabolism / Q000382:microbiology; D063191:Odonata / Q000276:immunology / Q000378:metabolism* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000276:immunology; D059467:Transcriptome; D014945:Wound Healing / Q000235:genetics
chemical_list: D019476:Insect Proteins