title: Sporadic Jakob-Creutzfeldt disease presenting as primary progressive aphasia.
abstract: OBJECTIVE
  To report the clinical, neuropsychological, linguistic, imaging, and neuropathological features of a unique case of sporadic Jakob-Creutzfeldt disease in which the patient presented with a logopenic variant of primary progressive aphasia.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Large referral center for atypical memory and aging disorders, particularly Jakob-Creutzfeldt disease.
  
  
  METHODS
  Patient presenting with logopenic variant primary progressive aphasia initially thought to be due to Alzheimer disease.
  
  
  RESULTS
  Despite the long, slow 3.5-year course, the patient was shown to have pathology-proven sporadic Jakob-Creutzfeldt disease.
  
  
  CONCLUSIONS
  These findings expand the differential of primary progressive aphasia to include prion disease.
authors: Department of Neurology, Memory and Aging Center, University of California, San Francisco, CA 94143-1207, USA.
authors: David Y
authors: DY
authors: Johnson
authors: Diana L
authors: DL
authors: Dunkelberger
authors: Maya
authors: M
authors: Henry
authors: Aissatou
authors: A
authors: Haman
authors: Michael D
authors: MD
authors: Greicius
authors: Katherine
authors: K
authors: Wong
authors: Stephen J
authors: SJ
authors: DeArmond
authors: Bruce L
authors: BL
authors: Miller
authors: Maria Luisa
authors: ML
authors: Gorno-Tempini
authors: Michael D
authors: MD
authors: Geschwind
mesh_terms: D018888:Aphasia, Primary Progressive / Q000150:complications* / Q000175:diagnosis* / Q000523:psychology; D007562:Creutzfeldt-Jakob Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000523:psychology; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests
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