title: Peculiarities in the Diagnosis Approach of MDS /MPN-U Patients.
abstract: The most recent WHO Classification of Tumors of Haematopoietic and Lymphoid Tissues describes a set of diseases framed as the MDS / MPN (myelodysplastic / chronic myeloproliferative syndromes). There are four subtypes comprised in this category: chronic myelomonocytic leukemia, juvenile myelomonocytic leukemia, atypical chronic myeloid leukemia and unclassifiable MDS / MPN. They combine both myelodysplastic and myeloproliferative features. Although the unclassifiable MDS/ MPN subtype specifically associates the myelodysplastic and myeloproliferative features, it does not meet the criteria defining the first 3 subtypes. The RARS-T subtype (refractory anemia with ringed sideroblasts associated with marked thrombocytosis) is included in the MDS / MPN-U as a temporary entity. There are two cases described in this article: one diagnosed with RARS-T and one with MDS / MPN-U. Both cases evolved towards acute myeloid leukemia.
authors: Department of Hematology, Coltea Clinical Hospital, Bucharest, Romania.
authors: Irina
authors: I
authors: Triantafyllidis
authors: Anca
authors: A
authors: Ciobanu
authors: Oana
authors: O
authors: Stanca
authors: Cecilia
authors: C
authors: Draghici
authors: Silvana
authors: S
authors: Angelescu
authors: Eliza
authors: E
authors: Tapelea
references: Ann Hematol. 2008 Jul;87(7):515-26
references: 18414863
references: Hematology Am Soc Hematol Educ Program. 2008;:52-9
references: 19074058