title: Nutritional predictors of acute respiratory infections among children born to HIV-infected women in Tanzania.
abstract: We prospectively determined the association between undernutrition and incidence of acute respiratory infections (ARIs) among 711 children born to HIV-infected women. Overall, underweight was associated with a 58% increased risk of ARI. Similarly, wasting (54%), very low birth weight (88%) and child HIV infection (62%) were significantly associated with increased risk of ARI during the first 2 years. Breastfeeding was associated with 52% reduction in risk of ARI only during the first 12 months of life. Among HIV-exposed, but uninfected, children, underweight, wasting and stunting were associated with 73%, 61% and 33% increased risk of ARI, respectively. Very low birthweight and advanced maternal disease stage were also associated with increased risk of ARI. Similar results were observed among HIV-infected children, except for stunting and very low birth weight. Prevention of child undernutrition could have major impact in reducing child ARI morbidity in settings of high HIV prevalence.
authors: Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA. rmwiru@gmail.com
authors: Ramadhani
authors: R
authors: Mwiru
authors: Donna
authors: D
authors: Spiegelman
authors: Ellen
authors: E
authors: Hertzmark
authors: Christopher
authors: C
authors: Duggan
authors: Gernard
authors: G
authors: Msamanga
authors: Said
authors: S
authors: Aboud
authors: Wafaie
authors: W
authors: Fawzi
mesh_terms: D000208:Acute Disease; D000328:Adult; D001942:Breast Feeding; D002675:Child, Preschool; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007223:Infant; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008297:Male; D044342:Malnutrition / Q000150:complications* / Q000453:epidemiology; D008423:Maternal Age; D015995:Prevalence; D011446:Prospective Studies; D012141:Respiratory Tract Infections / Q000150:complications* / Q000453:epidemiology; D012307:Risk Factors; D012959:Socioeconomic Factors; D013636:Tanzania / Q000453:epidemiology; D013851:Thinness
keywords: infections; nutrition; pediatrics; respiratory
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