title: [Effect of mechanical pressure-controled ventilation in patients with disturbed respiratory function during laparoscopic cholecystectomy].
abstract: OBJECTIVE
  Laparoscopic cholecystectomy is considered to be the gold standard for laparoscopic surgical procedures. In ASA III patients with concomitant respiratory diseases, however, creation of pneumoperitoneum and the position of patients during surgery exert additional negative effect on intraoperative respiratory function, thus making a higher challenge for the anesthesiologist than for the surgeon. The aim of this study was to compare the effect of intermittent positive pressure ventilation (IPPV) and pressure controlled ventilation (PCV) during general anesthesia on respiratory function in ASA III patients submitted to laparoscopic cholecystectomy.
  
  
  METHODS
  The study included 60 patients randomized into two groups depending on the mode of ventilation: IPPV or PCV. Respiratory volume (VT), peak inspiratory pressure (PIP), compliance (C), end-tidal CO2 pressure (PETCO2), oxygen saturation (SpO2), partial pressures of O2, CO2 (PaO2 and PaCO2) and pH of arterial blood were recorded within four time intervals.
  
  
  RESULTS
  There were no statistically significant differences in VT, SpO2, PaO2, PaCO2 and pH values neither within nor between the two groups. In time interval t1 there were no statistically significant differences in PIP, C, PETCO2 values between the IPPV and the PCV group. But, in the next three time intervals there was a difference in PIP, C, and PETCO2 values between the two groups which ranged from statistically significant to highly significant; PIP was lower, C and PETCO2 were higher in the PCV group.
  
  
  CONCLUSIONS
  Pressure controlled ventilation better maintains stability regarding intraoperative ventilatory parameters in ASA III patients with concomitant respiratory diseases during laparoscopic cholecystectomy.
authors: Klinika za anesteziologiju i intenzivnu terapiju, Beograd, Srbija. maja.surbatovic@gmail.com
authors: Maja
authors: M
authors: Surbatović
authors: Zoran
authors: Z
authors: Vesić
authors: Dragan
authors: D
authors: Djordjević
authors: Sonja
authors: S
authors: Radaković
authors: Snjezana
authors: S
authors: Zeba
authors: Dusko
authors: D
authors: Jovanović
authors: Marijan
authors: M
authors: Novaković
mesh_terms: D000328:Adult; D000368:Aged; D017081:Cholecystectomy, Laparoscopic; D005260:Female; D006801:Humans; D007385:Intermittent Positive-Pressure Ventilation; D007431:Intraoperative Complications / Q000209:etiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012120:Respiration Disorders / Q000209:etiology / Q000628:therapy*; D012121:Respiration, Artificial