title: High prevalence but low awareness of hepatitis C virus infection among heroin users who received methadone maintenance therapy in Taiwan.
abstract: BACKGROUND
  This study investigates the prevalence and correlates of hepatitis C virus (HCV) infections among heroin dependent individuals who received methadone maintenance therapy in Taiwan. Also, we investigate users' awareness of HCV.
  
  
  METHODS
  Participants were 773 heroin users entering the methadone maintenance treatment (MMT) program at Tsaotun Psychiatric Center in Taiwan. The presence of HCV antibodies was detected. Multivariate logistic regression was used to identify the relationship between HCV infection and correlates.
  
  
  RESULTS
  The prevalence of HCV infection was 90.8%. All participants who were HIV-positive were also infected with HCV. Multivariate logistic regression analysis showed that the route of heroin administration (injection), HIV-infection, and criminal records were significantly related to HCV infection. Few (34.8%) HCV positive heroin users were aware of their infection.
  
  
  CONCLUSIONS
  An extremely high prevalence of HCV infection but low awareness of their infection status was found among MMT patients in Taiwan. These findings highlight the importance of education regarding risky behaviors and the necessity for HCV treatment for this population in Taiwan.
authors: Tsaotun Psychiatric Center Department of Health, Nan-Tou 542, Taiwan. eenniidd_ng@yahoo.com.tw
authors: Mei-Hing
authors: MH
authors: Ng
authors: Jen-Yu
authors: JY
authors: Chou
authors: Ta-Jen
authors: TJ
authors: Chang
authors: Pei-Chin
authors: PC
authors: Lee
authors: Wen-Chuan
authors: WC
authors: Shao
authors: Tsang-Yaw
authors: TY
authors: Lin
authors: Vincent Chin-Hung
authors: VC
authors: Chen
authors: Michael
authors: M
authors: Gossop
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000627:therapeutic use; D057237:Criminals / Q000706:statistics & numerical data; D005260:Female; D015658:HIV Infections / Q000453:epidemiology; D007722:Health Knowledge, Attitudes, Practice; D006509:Hepatitis B / Q000453:epidemiology; D006526:Hepatitis C / Q000453:epidemiology* / Q000523:psychology; D006556:Heroin Dependence / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008691:Methadone / Q000627:therapeutic use; D008875:Middle Aged; D058850:Opiate Substitution Treatment; D015995:Prevalence; D012309:Risk-Taking; D015819:Substance Abuse, Intravenous / Q000453:epidemiology; D013624:Taiwan / Q000453:epidemiology
chemical_list: D000701:Analgesics, Opioid; D008691:Methadone