title: [Progressive multifocal leukoencephalopathy (review)].
abstract: The study is devoted to the problem of progressive multifocal leukoencephalopathy (PME) which in most cases is a fatal progressive demyelinating disease in the CNS. PME is an opportunity infection that develops during immunosuppression caused by chronic diseases or aggressive therapy. The authors consider possible mechanisms of the PME development, diagnosis of this disease and current approaches to treatment.
authors: M N
authors: MN
authors: Zakharova
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000276:immunology; D023241:Antiretroviral Therapy, Highly Active / Q000009:adverse effects; D015658:HIV Infections / Q000188:drug therapy; D006801:Humans; D007108:Immune Tolerance; D007165:Immunosuppression Therapy / Q000009:adverse effects; D007577:JC Virus / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology; D007968:Leukoencephalopathy, Progressive Multifocal / Q000175:diagnosis* / Q000276:immunology* / Q000473:pathology; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000276:immunology* / Q000473:pathology