title: IgE-mediated reaction to local anaesthetics.
abstract: Local anaesthetics (LAs) are essential agents in daily practices of dentistry, minor surgery and dermatology. Although they have an impressive history of safety and efficacy, LAs also have the potential to produce adverse events, which are mainly of non-immune nature. The true IgE-mediated allergies are quite rare, but are more considerable in terms of ability to cause life-threatening outcomes. In this report, we present a case of IgE-mediated systemic reaction to LAs occurring during epidural anaesthesia for Cesarean section.
authors: Division of Immunology and Allergic Disease, Gulhane Military Medical Academy and Medical School, Ankara, Turkey.
authors: Ozgur
authors: O
authors: Kartal
authors: Mustafa
authors: M
authors: Gulec
authors: Ahmet Zafer
authors: AZ
authors: Caliskaner
authors: Osman
authors: O
authors: Sener
mesh_terms: D000328:Adult; D000767:Anesthesia, Epidural / Q000009:adverse effects*; D000779:Anesthetics, Local / Q000009:adverse effects* / Q000276:immunology; D002045:Bupivacaine / Q000009:adverse effects*; D002585:Cesarean Section; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage; D006634:Histamine H1 Antagonists / Q000008:administration & dosage; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D008012:Lidocaine / Q000009:adverse effects*; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D011247:Pregnancy; D012882:Skin Tests; D016896:Treatment Outcome
chemical_list: D000779:Anesthetics, Local; D005938:Glucocorticoids; D006634:Histamine H1 Antagonists; D007073:Immunoglobulin E; D008012:Lidocaine; D008775:Methylprednisolone; D002045:Bupivacaine