title: Long-term dynamics of CA1 hippocampal place codes.
abstract: Using Ca(2+) imaging in freely behaving mice that repeatedly explored a familiar environment, we tracked thousands of CA1 pyramidal cells' place fields over weeks. Place coding was dynamic, as each day the ensemble representation of this environment involved a unique subset of cells. However, cells in the ∼15-25% overlap between any two of these subsets retained the same place fields, which sufficed to preserve an accurate spatial representation across weeks.
authors: James H. Clark Center, Stanford University, Stanford, California, USA.
authors: Yaniv
authors: Y
authors: Ziv
authors: Laurie D
authors: LD
authors: Burns
authors: Eric D
authors: ED
authors: Cocker
authors: Elizabeth O
authors: EO
authors: Hamel
authors: Kunal K
authors: KK
authors: Ghosh
authors: Lacey J
authors: LJ
authors: Kitch
authors: Abbas
authors: A
authors: El Gamal
authors: Mark J
authors: MJ
authors: Schnitzer
mesh_terms: D000200:Action Potentials / Q000502:physiology*; D000818:Animals; D056547:CA1 Region, Hippocampal / Q000502:physiology*; D002118:Calcium / Q000378:metabolism*; D004777:Environment; D008568:Memory / Q000502:physiology; D051379:Mice; D017966:Pyramidal Cells / Q000502:physiology*
chemical_list: D002118:Calcium
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