title: BION web server: predicting non-specifically bound surface ions.
abstract: BACKGROUND
  Ions are essential component of the cell and frequently are found bound to various macromolecules, in particular to proteins. A binding of an ion to a protein greatly affects protein's biophysical characteristics and needs to be taken into account in any modeling approach. However, ion's bounded positions cannot be easily revealed experimentally, especially if they are loosely bound to macromolecular surface.
  
  
  RESULTS
  Here, we report a web server, the BION web server, which addresses the demand for tools of predicting surface bound ions, for which specific interactions are not crucial; thus, they are difficult to predict. The BION is easy to use web server that requires only coordinate file to be inputted, and the user is provided with various, but easy to navigate, options. The coordinate file with predicted bound ions is displayed on the output and is available for download.
authors: Computational Biophysics and Bioinformatics, Department of Physics and Astronomy, Clemson University, Clemson, SC 29634, USA.
authors: Marharyta
authors: M
authors: Petukh
authors: Taylor
authors: T
authors: Kimmet
authors: Emil
authors: E
authors: Alexov
mesh_terms: D000465:Algorithms; D001665:Binding Sites; D020407:Internet; D007477:Ions / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*; D012984:Software; D055672:Static Electricity
chemical_list: D007477:Ions; D011506:Proteins
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