title: Usefulness of magnifying endoscopy with narrow-band imaging for determining tumor invasion depth in early gastric cancer.
abstract: Backgrounds. Magnifying endoscopy with narrow-band imaging (ME-NBI) has become essential for determining tumor margin in early gastric cancer (EGC). Here, we investigated the usefulness of ME-NBI for assessment of invasion depth in EGC. Methods. For 119 patients who had undergone ME-NBI and en bloc resection by endoscopic submucosal dissection, three physicians prospectively examined high-magnification ME-NBI images for clinical features such as presence or absence of dilated vessels (D vessels). Cases with D vessels verified by at least two physicians were assigned to group V, and others were assigned to group N. We then compared clinicopathological factors associated with the groups. Results. Groups V and N consisted of 18 and 101 patients, respectively. There were no significant differences in age, gender, tumor size, tumor location, gross morphology, or histological type. The percentage of submucosal cancer was 9.9% (10/101) in group N and significantly higher at 33.3% (6/18) in group V (P = 0.007). When the presence of D vessels was considered a diagnostic criterion for submucosal cancer, diagnostic accuracy, sensitivity, and specificity were 81.5, 37.5, and 88.3%, respectively. Conclusions. The results suggest that identification of D vessels using ME-NBI can assist in the assessment of invasion depth in EGC.
authors: Department of Gastroenterology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo 105-8470, Japan ; Department of Gastroenterology, Juntendo University, Tokyo 113-0033, Japan.
authors: Daisuke
authors: D
authors: Kikuchi
authors: Toshiro
authors: T
authors: Iizuka
authors: Shu
authors: S
authors: Hoteya
authors: Akihiro
authors: A
authors: Yamada
authors: Tsukasa
authors: T
authors: Furuhata
authors: Satoshi
authors: S
authors: Yamashita
authors: Kaoru
authors: K
authors: Domon
authors: Masanori
authors: M
authors: Nakamura
authors: Akira
authors: A
authors: Matsui
authors: Toshifumi
authors: T
authors: Mitani
authors: Osamu
authors: O
authors: Ogawa
authors: Sumio
authors: S
authors: Watanabe
authors: Mitsuru
authors: M
authors: Kaise
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