title: High-intensity focused ultrasound: advances in technology and experimental trials support enhanced utility of focused ultrasound surgery in oncology.
abstract: High-intensity focused ultrasound (HIFU) is a rapidly maturing technology with diverse clinical applications. In the field of oncology, the use of HIFU to non-invasively cause tissue necrosis in a defined target, a technique known as focused ultrasound surgery (FUS), has considerable potential for tumour ablation. In this article, we outline the development and underlying principles of HIFU, overview the limitations and commercially available equipment for FUS, then summarise some of the recent technological advances and experimental clinical trials that we predict will have a positive impact on extending the role of FUS in cancer therapy.
authors: Department of Surgery and Cancer, Faculty of Medicine, Imperial College, London, UK.
authors: G
authors: G
authors: Malietzis
authors: L
authors: L
authors: Monzon
authors: J
authors: J
authors: Hand
authors: H
authors: H
authors: Wasan
authors: E
authors: E
authors: Leen
authors: M
authors: M
authors: Abel
authors: A
authors: A
authors: Muhammad
authors: P
authors: P
authors: Price
authors: P
authors: P
authors: Abel
mesh_terms: D002986:Clinical Trials as Topic; D019317:Evidence-Based Medicine / Q000639:trends*; D057086:High-Intensity Focused Ultrasound Ablation / Q000706:statistics & numerical data*; D006801:Humans; D008495:Medical Oncology / Q000639:trends*; D009369:Neoplasms / Q000601:surgery*; D013673:Technology Assessment, Biomedical; D016896:Treatment Outcome
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