title: Congenital lung lesions: preoperative three-dimensional reconstructed CT scan as the definitive investigation and surgical management.
abstract: OBJECTIVE
  The aim of this study was to review our experience of postnatal investigations and management of congenital lung lesions.
  
  
  METHODS
  All children with antenatal diagnosis undergoing surgical management were identified from hospital records. Antenatal diagnosis and serial antenatal ultrasound findings were noted, postnatal chest X-ray (CXR) and computed tomographic (CT) scan were reviewed. Pearson correlation coefficient (r) was used to look into relation between CT scan and per-operative findings. Surgical management and outcome of these lesions were assessed.
  
  
  RESULTS
  A total of 38 children were identified between January 2000 and December 2011; 22 were males and 16 were females. The mean gestational age at diagnosis was 21 weeks (range 18 to 26 weeks). Five children showed complete resolution antenatally. Four children were symptomatic at birth. Postnatal CXR showed an abnormality in only 17 infants. CT scan with three-dimensional (3D) reconstructions was performed at the mean age of 7.7 months (range 1 day to 42 months). CT scan correlated well with per-operative findings and provided adequate anatomical information r = 0.98. Open thoracotomy and lobectomy/excision was performed in 23, and 15 had thoracoscopic lobectomy/excision. The mean age of operation was 18 months (range 2 days to 96 months). Twenty patients had signs of recurrent preoperative infection with pleural adhesions and hilar thickening resulting in conversion of 10 thoracoscopic cases to open surgery. Histology confirmed 26 congenital cystic adenomatoid malformations, 2 hybrid lesions, 7 sequestrations, and 3 bronchopulmonary malformations.
  
  
  CONCLUSIONS
  Antenatal resolution and normal postnatal CXR are not reliable indicators of resolution of the lesion. Early postnatal CT scan preferably with 3D reconstruction and early surgical treatment are suggested, as delaying the operation may result in repeated infection making thoracoscopic approach more difficult.
authors: Department of Paediatric Surgery, Addenbrooke's Hospital Cambridge, Hills Road, Cambridge, United Kingdom.
authors: Atif
authors: A
authors: Saeed
authors: Marcin
authors: M
authors: Kazmierski
authors: Abdul
authors: A
authors: Khan
authors: Donna
authors: D
authors: McShane
authors: Anna
authors: A
authors: Gomez
authors: Adil
authors: A
authors: Aslam
mesh_terms: D058070:Asymptomatic Diseases; D001998:Bronchopulmonary Sequestration / Q000000981:diagnostic imaging* / Q000601:surgery; D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000000981:diagnostic imaging* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D021621:Imaging, Three-Dimensional; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011013:Pneumonectomy / Q000379:methods; D011247:Pregnancy; D011300:Preoperative Care; D012189:Retrospective Studies; D013906:Thoracoscopy; D013908:Thoracotomy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D016216:Ultrasonography, Prenatal