title: Independent predictors of complication following surgery for spinal metastasis.
abstract: OBJECTIVE
  Surgery for spinal metastasis is often associated with significant morbidity. Despite a number of preoperative scoring systems/scales and identified variables that have been reported to predict complication risk, clinical studies that directly evaluate this issue using multivariate analysis are scarce. The goal of our study was to assess independent predictors of complication after surgery for spinal metastasis.
  
  
  METHODS
  We queried electronic medical records to identify a consecutive population of adult patients who underwent surgery for spinal metastasis for the period June 2005 through June 2011. Utilizing multivariate logistic regression, we assessed independent predictors of perioperative and postoperative adverse events.
  
  
  RESULTS
  A total of 106 patients were included in the final analysis. Overall complication rate was 21.7 %. Independent predictors for higher rates of complication were age greater than 40 years [40-65 years had odds ratio (OR) 1.91, 95 % confidence interval (CI) 1.02-16.78 and >65 years had OR 5.17, 95 % CI 1.54-29.81] and metastatic lesions involving three or more contiguous levels of the spine (OR 2.76, 95 % CI 1.09-9.61).
  
  
  CONCLUSIONS
  Patients older than 40 years or patients who have metastatic lesions involving three or more contiguous vertebral levels appear to be at higher risk for complication. Patients older than 65 years have the greatest likelihood of complication.
authors: University of Michigan Medical School, Ann Arbor, MI, USA.
authors: Darryl
authors: D
authors: Lau
authors: Matthew R
authors: MR
authors: Leach
authors: Khoi D
authors: KD
authors: Than
authors: John
authors: J
authors: Ziewacz
authors: Frank
authors: F
authors: La Marca
authors: Paul
authors: P
authors: Park
mesh_terms: D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D019637:Orthopedic Procedures; D011183:Postoperative Complications / Q000453:epidemiology*; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D013125:Spinal Neoplasms / Q000556:secondary* / Q000601:surgery*; D016896:Treatment Outcome
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