title: Unspecific, idiopathic isolated osteolysis (Gorham-Stout syndrome) of the mandibular condylar process with its radiological, histological and clinical features: a case report and review of literature.
abstract: BACKGROUND
  The unspecific, idiopathic isolated osteolysis is a rare condition in the various known osteopathies and better known as Gorham-Stout syndrome (Gorham's disease, GD). It belongs to the primary idiopathic osteolysis, and its aetiology is poorly understood. Many different localisations have been described, but there are only 48 cases affecting the maxillofacial region until now.
  
  
  METHODS
  A 76-year-old patient with the singular localisation of GD in the left condylar process is presented. After radical resection of the condylar process, the clinical, radiological and pathological examinations made the diagnosis of GD. Until now, there is no recurrence for two and a half years.
  
  
  CONCLUSIONS
  The unspecific and inconsistent clinical and radiological symptoms complicate the diagnosis of GD. Clinical, pathological and radiological correlation is essential to make the diagnosis. The different therapeutical options and the specific outcome are discussed.
authors: Department of Oral and Maxillofacial Surgery and Facial Plastic Surgery, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle, Germany, konstanze.weinzierl@medizin.uni-halle.de.
authors: Konstanze
authors: K
authors: Scheller
authors: Peter
authors: P
authors: Herrmann-Trost
authors: Linda
authors: L
authors: Diesel
authors: Christin
authors: C
authors: Busse
authors: Christian
authors: C
authors: Heinzelmann
mesh_terms: D051997:ADP-ribosyl Cyclase 1 / Q000032:analysis; D000368:Aged; D002196:Capillaries / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D019394:Ki-67 Antigen / Q000032:analysis; D042601:Lymphatic Vessels / Q000473:pathology; D008297:Male; D008335:Mandibular Condyle / Q000000981:diagnostic imaging* / Q000473:pathology*; D008562:Membrane Glycoproteins / Q000032:analysis; D010010:Osteoclasts / Q000473:pathology; D010015:Osteolysis, Essential / Q000000981:diagnostic imaging* / Q000473:pathology*; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000032:analysis*; D011862:Radiography, Panoramic; D014057:Tomography, X-Ray Computed
chemical_list: D019394:Ki-67 Antigen; D008562:Membrane Glycoproteins; D019408:Platelet Endothelial Cell Adhesion Molecule-1; C498154:CD38 protein, human; D051997:ADP-ribosyl Cyclase 1
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