title: Liver resection and transplantation offer similar 5-year survival for Child-Pugh-Turcotte A HCC-patients with a single nodule up to 5 cm: a multicenter, exploratory analysis.
abstract: OBJECTIVE
  The current guideline of the American Association for the Study of Liver Diseases recommends liver resection for Child-Pugh-Turcotte A patients with a single hepatocellular carcinoma, total serum bilirubin ≤ 1 mg/dL and absence of significant portal hypertension. This subset of patients would have a long-term survival comparable to transplantation. The main aim of this study is to evaluate the survival rates in patients with a single nodule ≤ 5 cm following resection.
  
  
  METHODS
  Medical records of 105 Child-Pugh-Turcotte A patients who underwent liver resection between 1997 and 2009 were analyzed in 3 countries.
  
  
  RESULTS
  One, 3-, and 5-year survival rate was 97%, 83%, and 66%, respectively, and no variable that can be assessed prior to liver resection predicted survival probabilities.
  
  
  CONCLUSIONS
  Liver resection offers 5-year survival similar to transplantation for Child-Pugh-Turcotte A patients with hepatocellular carcinoma and a single nodule up to 5 cm, independently of any patient baseline characteristics.
authors: Department of Gastroenterology, Flinders University, Adelaide, Australia. mauriciosilva11@yahoo.com.br
authors: M F
authors: MF
authors: Silva
authors: G
authors: G
authors: Sapisochin
authors: S I
authors: SI
authors: Strasser
authors: S
authors: S
authors: Hewa-Geeganage
authors: J
authors: J
authors: Chen
authors: A J
authors: AJ
authors: Wigg
authors: R
authors: R
authors: Jones
authors: R
authors: R
authors: Saraiva
authors: L
authors: L
authors: Kikuchi
authors: F
authors: F
authors: Carrilho
authors: P R O
authors: PR
authors: Fontes
authors: R
authors: R
authors: Charco
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001315:Australia; D001938:Brazil; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D006498:Hepatectomy; D006801:Humans; D008103:Liver Cirrhosis / Q000473:pathology / Q000601:surgery*; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012189:Retrospective Studies; D013030:Spain; D016019:Survival Analysis