title: A unique presentation of Epstein-Barr virus-associated Castleman's disease.
abstract: Castleman's disease (CD) is a rare, benign lymphoproliferative disorder. The association of human herpes virus 8 (HHV8) and human immunodeficiency virus infections with CD is well established however the role of Epstein-Barr Virus in CD is less well understood. We present a unique case of Castleman's disease in a patient with concomitant EBV infection, which mimicked the clinical presentation of nasopharyngeal carcinoma (NPC) versus lymphoma. After a delayed diagnosis, the patient underwent a left superficial parotidectomy and neck dissection and has had no recurrence of disease.
authors: Department of Otolaryngology-Head & Neck Surgery, Tufts Medical Center, Boston, MA, USA.
authors: Heather
authors: H
authors: Gomes
authors: Phillip
authors: P
authors: Huyett
authors: Nora
authors: N
authors: Laver
authors: Richard O
authors: RO
authors: Wein
mesh_terms: D000368:Aged; D005871:Castleman Disease / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology / Q000821:virology*; D057210:Delayed Diagnosis; D018450:Disease Progression; D020031:Epstein-Barr Virus Infections / Q000150:complications*; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D010306:Parotid Gland / Q000601:surgery