title: Regio- and stereoselective synthesis of 2-cyclopentenones via a hydrogenolysis-terminated Heck cyclization of β-alkylthio dienones.
abstract: Palladium-catalyzed cyclization of β-alkylthio dienone derivatives affords 2-cyclopentenones in a regio- and stereoselective manner in the presence of silane. C-S activation, intramolecular carbopalladation and hydrogenolysis construct the cascade process.
authors: Faculty of Chemistry, Northeast Normal University, Changchun 130024, PR China.
authors: Bangyu
authors: B
authors: Liu
authors: Gang
authors: G
authors: Zheng
authors: Xiaocui
authors: X
authors: Liu
authors: Cong
authors: C
authors: Xu
authors: Jingxin
authors: J
authors: Liu
authors: Mang
authors: M
authors: Wang
mesh_terms: D002384:Catalysis; D003500:Cyclization; D003517:Cyclopentanes / Q000138:chemical synthesis* / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry; D012821:Silanes / Q000737:chemistry; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D003517:Cyclopentanes; D007659:Ketones; D012821:Silanes; D013438:Sulfhydryl Compounds; D010165:Palladium; D006859:Hydrogen; C013905:cyclopentenone