title: Reflections on substrate water and dioxygen formation.
abstract: This brief article aims at presenting a concise summary of all experimental findings regarding substrate water-binding to the Mn4CaO5 cluster in photosystem II. Mass spectrometric and spectroscopic results are interpreted in light of recent structural information of the water oxidizing complex obtained by X-ray crystallography, spectroscopy and theoretical modeling. Within this framework current proposals for the mechanism of photosynthetic water-oxidation are evaluated. This article is part of a Special Issue entitled: Metals in Bioenergetics and Biomimetics Systems.
authors: Max-Planck-Institut für Chemische Energiekonversion, Stiftstrasse 34-36, Mülheim an der Ruhr, Germany.
authors: Nicholas
authors: N
authors: Cox
authors: Johannes
authors: J
authors: Messinger
mesh_terms: D001665:Binding Sites; D013058:Mass Spectrometry; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D014867:Water; D010100:Oxygen
keywords: Mechanism of water oxidation; Mn(4)CaO(5) cluster; Oxygen evolving complex (OEC); Photosystem II; Substrate water binding; Water oxidizing complex (WOC)