title: Infection of cattle with Border disease virus by sheep on communal alpine pastures.
abstract: The purpose of this study was to investigate whether sheep grazing communal alpine pastures with cattle can transmit Border disease virus (BDV) to cattle. A total of 1170 sheep and 923 cattle were tested for BDV using RT-PCR (sheep) and for pestivirus antibodies using an ELISA (cattle), respectively, before being moved to one of 4 pastures (A, B, C and D). Eight sheep from pasture C were viraemic. 396 of 923 cattle examined before the pasture season were seronegative. The latter were re-examined after the pasture season and 99 were seropositive or indeterminate. Antibody specificity was determined in 25 of these using a serum neutralization test (SNT). BDV infection was confirmed in 10 cattle and was considered likely in 8 others. BVDV infection was confirmed in 4 cattle and considered likely in 3 after pasturing. The study has shown that the transmission of BDV from sheep to cattle is possible on communal alpine pastures.
authors: Department of Farm Animals, University of Zurich. ubraun@vetclinics.uzh.ch
authors: U
authors: U
authors: Braun
authors: C
authors: C
authors: Bachofen
authors: R
authors: R
authors: Büchi
authors: M
authors: M
authors: Hässig
authors: E
authors: E
authors: Peterhans
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D001882:Border Disease / Q000453:epidemiology / Q000635:transmission* / Q000821:virology; D018083:Border disease virus / Q000235:genetics / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology / Q000821:virology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D012367:RNA, Viral / Q000097:blood; D012307:Risk Factors; D012621:Seasons; D016036:Seroepidemiologic Studies; D012756:Sheep; D013557:Switzerland / Q000453:epidemiology; D019562:Viral Load
chemical_list: D000914:Antibodies, Viral; D012367:RNA, Viral