title: Early tendon transfer after wide resection of an undifferentiated sarcoma of the forearm in a neonate: a case report.
abstract: A 1-month-old female baby was diagnosed with an undifferentiated sarcoma of her forearm after incisional biopsy. She received five cycles of chemotherapy before a wide resection of her extensor muscles including the radial nerve was undertaken, resulting in a complete drop of wrist and fingers. At this stage, primary tendon transfer of the brachioradialis to extensor carpi radial brevis muscle was performed, which proved to be not sufficient. Five months after resection of the tumour, restoration of the extensor function was achieved by flexor tendon transfers to provide wrist, finger and thumb extension. After 2 years, the patient did not show any signs of recurrence and she has a good wrist, finger and thumb extension and flexion. The diagnosis of an undifferentiated sarcoma is one per exclusion. Treatment includes chemotherapy and complete resection of the tumour with a wide margin. We discuss the diagnosis of undifferentiated sarcoma as well as early restoration of hand function in neonates.
authors: Department of Plastic Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands. acmvanbommel@gmail.com
authors: Annelotte
authors: A
authors: van Bommel
authors: Riffat
authors: R
authors: Aslam
authors: Marie-Anne
authors: MA
authors: Brundler
authors: David
authors: D
authors: Hobin
authors: Andrea
authors: A
authors: Jester
mesh_terms: D001707:Biopsy, Needle; D005260:Female; D005500:Follow-Up Studies; D005542:Forearm / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007231:Infant, Newborn; D016059:Range of Motion, Articular / Q000502:physiology; D035583:Rare Diseases; D019651:Plastic Surgery Procedures / Q000379:methods; D020127:Recovery of Function; D018570:Risk Assessment; D012509:Sarcoma / Q000473:pathology* / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000473:pathology* / Q000601:surgery*; D013709:Tendon Transfer / Q000379:methods*; D013997:Time Factors; D016896:Treatment Outcome
keywords: Forearm; Neonate; Tendon transfer; Undifferentiated sarcoma