title: Biodegradation of bisphenol A by Heliscus lugdunensis, a naturally occurring hyphomycete in freshwater environments.
abstract: Bisphenol A (BPA) is an environmental contaminant that has been under investigation for its detrimental effect on the aquatic ecosystem. In this study, an aquatic fungus, Heliscus lugdunensis Saccardo & Therry (live and heat-inactivated by autoclaving) was evaluated for its ability to utilize BPA as a carbon source. Both live and heat-inactivated fungal cultures were exposed to 10 mg L(-1) bisphenol A after cultivation in glucose for 3d. Extraction of BPA in the medium was carried out using PrepSep™ C-18 mini columns followed by quantification of recovered BPA by high performance liquid chromatography after sample clean-up. While heat inactivation sufficiently disrupts the ability of the fungal cells to utilize BPA, the live fungal cultures removed over 70% of BPA after 12d. Our results suggest that H. lugdunensis is capable of biodegrading BPA and utilizing it as an energy source.
authors: Department of Chemistry, Division of Natural Sciences & Engineering, University of South Carolina Upstate, Spartanburg, SC 29303, USA. aomoike@uscupstate.edu
authors: A
authors: A
authors: Omoike
authors: T
authors: T
authors: Wacker
authors: M
authors: M
authors: Navidonski
mesh_terms: D001559:Benzhydryl Compounds / Q000378:metabolism*; D001673:Biodegradation, Environmental; D002851:Chromatography, High Pressure Liquid; D004784:Environmental Monitoring; D055330:Nectria / Q000187:drug effects* / Q000378:metabolism*; D010636:Phenols / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000378:metabolism*; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D010636:Phenols; D014874:Water Pollutants, Chemical; C006780:bisphenol A; D000098826:Bisphenol A Compounds