title: Prognostic factors for clinical outcomes according to time after direct pulp capping.
abstract: BACKGROUND
  Direct pulp capping is a treatment option for teeth with carious-exposed pulp. Because pulp capping studies have exhibited fluctuations in success rates according to different follow-up times, investigating the clinical pulpal survival rate and the potential factors contributing to the survival with respect to time is necessary.
  
  
  METHODS
  A total of 175 patients treated between November 2007 and August 2010 met the inclusion criteria. During the follow-up, we investigated 7 clinical variables with respect to the survival of the pulp capping treatment: sex, age, maxilla versus mandible, tooth position, capping materials, temporary filling materials, and exposure site. Survival analysis was performed using the Kaplan-Meier method and the Cox proportional hazard regression model.
  
  
  RESULTS
  The Kaplan-Meier survival curves and log-rank tests revealed that only age, exposure site, and capping material had significant effects on the pulpal survival rate (P< .05). A Cox regression model showed that mineral trioxide aggregate was the sole factor affecting the survival of the treated pulps (P< .05). In the analyses performed separately according to time, there was no conspicuous factor that affected the survival rate before 100 days. However, after 100 days, the type of pulp capping material was the single most important factor influencing the survival rate (P< .05).
  
  
  CONCLUSIONS
  The results of this study indicated that careful patient selection and the type of pulp capping material should be taken into consideration when performing a pulp capping treatment.
authors: Department of Conservative Dentistry and Oral Science Research Center, College of Dentistry, Yonsei University, Seoul, Korea.
authors: Sin-Yeon
authors: SY
authors: Cho
authors: Deog-Gyu
authors: DG
authors: Seo
authors: Shin-Jae
authors: SJ
authors: Lee
authors: Junghyun
authors: J
authors: Lee
authors: Seung-Jong
authors: SJ
authors: Lee
authors: Il-Young
authors: IY
authors: Jung
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D017607:Aluminum Compounds / Q000627:therapeutic use; D017610:Calcium Compounds / Q000627:therapeutic use; D003785:Dental Pulp Capping / Q000379:methods*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D010087:Oxides / Q000627:therapeutic use; D011379:Prognosis; D016016:Proportional Hazards Models; D012388:Root Canal Irrigants / Q000627:therapeutic use; D017640:Silicates / Q000627:therapeutic use; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012388:Root Canal Irrigants; D017640:Silicates; C086631:mineral trioxide aggregate