title: Evaluation of right ventricular functions in patients with nasal polyposis: an observational study.
abstract: OBJECTIVE
  The aim of this study was to assess the right ventricular functions in patients with nasal polyposis using the strain (S) and strain rate (SR) echocardiography.
  
  
  METHODS
  A prospective, cross-sectional observational study was performed. The study included 40 patients with nasal polyposis (NP) (Group 1), and 25 healthy controls (Group 2). The study comprised patients with Stage 2 and Stage 3 nasal obstruction and no symptoms that could be associated with right ventricular heart failure. Longitudinal peak systolic strain (PSS) and peak systolic strain rate (PSSR) were measured from the basal-mid and apical segments of the right ventricle free wall. Student's t-test, Pearson's correlation analysis and Bland-Altman test were used for statistical analysis.
  
  
  RESULTS
  Pulmonary arterial systolic pressure was significantly higher in group 1 than group 2 (31.2 ± 5.8, 19.7 ± 4.3, respectively, p<0.001). PSS and PSSR values at the basal, mid and apical segments of the right ventricular lateral wall of the group I were significantly lower compared to the control group (p<0.001, p=0.002 and p=0.002 for PSS, p=0.003, p<0.001 and p<0.001 for PSSR, respectively). The comparison of Stage 2 and Stage 3 NP patients revealed a significant difference only in the SR measurement of the right ventricular mid segment (p=0.002). There was a significant correlation between the systolic pulmonary arterial pressure (sPAP) and right ventricular S and SR values (p<0.001).
  
  
  CONCLUSIONS
  In this study, S/SR echocardiography showed a subclinical deficit of the right ventricular longitudinal functions in patients with NP who are considered to have normal right ventricular functions.
authors: Clinic of Ear, Nose and Throat, Erzurum Region Education and Research Hospital, Erzurum, Turkey. hekimeda@hotmail.com
authors: Eda
authors: E
authors: Şimşek
authors: Ziya
authors: Z
authors: Şimşek
authors: M Hakan
authors: MH
authors: Taş
authors: Cüneyt
authors: C
authors: Kucur
authors: Ersin
authors: E
authors: Günay
authors: Harun
authors: H
authors: Üçüncü
mesh_terms: D000293:Adolescent; D000328:Adult; D000402:Airway Obstruction; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps; D011446:Prospective Studies; D018497:Ventricular Dysfunction, Right / Q000000981:diagnostic imaging / Q000503:physiopathology*