title: Computational proteomics pitfalls and challenges: HavanaBioinfo 2012 workshop report.
abstract: The workshop "Bioinformatics for Biotechnology Applications (HavanaBioinfo 2012)", held December 8-11, 2012 in Havana, aimed at exploring new bioinformatics tools and approaches for large-scale proteomics, genomics and chemoinformatics. Major conclusions of the workshop include the following: (i) development of new applications and bioinformatics tools for proteomic repository analysis is crucial; current proteomic repositories contain enough data (spectra/identifications) that can be used to increase the annotations in protein databases and to generate new tools for protein identification; (ii) spectral libraries, de novo sequencing and database search tools should be combined to increase the number of protein identifications; (iii) protein probabilities and FDR are not yet sufficiently mature; (iv) computational proteomics software needs to become more intuitive; and at the same time appropriate education and training should be provided to help in the efficient exchange of knowledge between mass spectrometrists and experimental biologists and bioinformaticians in order to increase their bioinformatics background, especially statistics knowledge.
authors: Yasset
authors: Y
authors: Perez-Riverol
authors: Henning
authors: H
authors: Hermjakob
authors: Oliver
authors: O
authors: Kohlbacher
authors: Lennart
authors: L
authors: Martens
authors: David
authors: D
authors: Creasy
authors: Jürgen
authors: J
authors: Cox
authors: Felipe
authors: F
authors: Leprevost
authors: Baozhen Paul
authors: BP
authors: Shan
authors: Violeta I
authors: VI
authors: Pérez-Nueno
authors: Michal
authors: M
authors: Blazejczyk
authors: Marco
authors: M
authors: Punta
authors: Klemens
authors: K
authors: Vierlinger
authors: Pedro A
authors: PA
authors: Valiente
authors: Kalet
authors: K
authors: Leon
authors: Glay
authors: G
authors: Chinea
authors: Osmany
authors: O
authors: Guirola
authors: Ricardo
authors: R
authors: Bringas
authors: Gleysin
authors: G
authors: Cabrera
authors: Gerardo
authors: G
authors: Guillen
authors: Gabriel
authors: G
authors: Padron
authors: Luis Javier
authors: LJ
authors: Gonzalez
authors: Vladimir
authors: V
authors: Besada
mesh_terms: D019295:Computational Biology / Q000379:methods* / Q000639:trends; D003226:Congresses as Topic; D003462:Cuba; D040901:Proteomics / Q000379:methods* / Q000639:trends