title: Calreticulin and cancer.
abstract: Calreticulin (CRT) as a multi-functional endoplasmic reticulum protein is involved in a spectrum of cellular processes which ranges from calcium homeostasis and chaperoning to cell adhesion and finally malignant formation and progression. Previous studies have shown a contributing role for CRT in a range of different cancers. This present review will focus on the possible roles of CRT in the progression of malignant proliferation and the mechanisms involved in its contribution to cancer invasion.
authors: Genetic Medicine Research Center, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia.
authors: Mohammadreza
authors: M
authors: Zamanian
authors: Abhi
authors: A
authors: Veerakumarasivam
authors: Syahril
authors: S
authors: Abdullah
authors: Rozita
authors: R
authors: Rosli
mesh_terms: D037282:Calreticulin / Q000378:metabolism*; D063646:Carcinogenesis / Q000378:metabolism* / Q000473:pathology; D004721:Endoplasmic Reticulum / Q000378:metabolism / Q000473:pathology; D006801:Humans; D009369:Neoplasms / Q000378:metabolism*
chemical_list: D037282:Calreticulin
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