title: A chemist and biologist talk to each other about caged neurotransmitters.
abstract: Caged compounds are small organic molecules that can be photoactivated with brief pulses of light. They are widely used to study a great variety of biological processes by physiologists, cell biologists and neuroscientists. Initially made and invented by biologists in the late 1970s, they are now made mostly by chemists, often without any dialogue with the end users, the biologists. The idea for this review is to stimulate interaction between the two communities to further the creative development and application of these powerful optical probes.
authors: Department of Neuroscience, Mount Sinai School of Medicine, One Gustave Levy Place, New York, NY 10029, USA.
authors: Graham Cr
authors: GC
authors: Ellis-Davies
keywords: caged compounds; cell signaling; electrophysiology; neuronal currents; photolabile neurotransmitters; rates of reaction; receptor antagonism
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