title: Chronic eosinophilic pneumonia presenting with acute onset.
abstract: A 44-year-old woman was hospitalized with a 2-day history of cough, sputum, and fever. There was no history of atopic dermatitis or asthma. On admission, the chest X-ray revealed scattered infiltration in the left upper lung fields. Further examination revealed peripheral blood and bronchoalveolar lavage fluid eosinophilia. Transbronchial lung biopsy revealed eosinophilic pneumonia, with eosinophil infiltration of the alveoli, destroyed basal lumina, and connecting intraluminal fibrosis of the alveolar walls. Based on the findings, we made the diagnosis of chronic eosinophilic pneumonia. Treatment with prednisolone at 60 mg/day resulted in dramatic improvement of both the symptoms and the radiologic abnormalities.
authors: Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo. kumasawa.fumio@nihon-u.ac.jp
authors: Fumio
authors: F
authors: Kumasawa
authors: Tomoko
authors: T
authors: Kobayashi
authors: Akihiro
authors: A
authors: Noda
authors: Yoshitaka
authors: Y
authors: Shintani
authors: Daisuke
authors: D
authors: Koyama
authors: Takashi
authors: T
authors: Oki
authors: Kenji
authors: K
authors: Mizumura
authors: Susumu
authors: S
authors: Nishinarita
authors: Tatsuo
authors: T
authors: Sawada
authors: Shu
authors: S
authors: Hashimoto
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D018893:Bronchoalveolar Lavage; D004804:Eosinophils / Q000276:immunology / Q000473:pathology*; D005260:Female; D005355:Fibrosis; D006801:Humans; D011239:Prednisolone / Q000008:administration & dosage*; D011650:Pulmonary Alveoli / Q000473:pathology*; D011657:Pulmonary Eosinophilia / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology*
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone