title: Introduced Siberian chipmunks (Tamias sibiricus barberi) contribute more to lyme borreliosis risk than native reservoir rodents.
abstract: The variation of the composition in species of host communities can modify the risk of disease transmission. In particular, the introduction of a new host species can increase health threats by adding a new reservoir and/or by amplifying the circulation of either exotic or native pathogens. Lyme borreliosis is a multi-host vector-borne disease caused by bacteria belonging to the Borrelia burgdorferi sensu lato complex. It is transmitted by the bite of hard ticks, especially Ixodes ricinus in Europe. Previous studies showed that the Siberian chipmunk, Tamias sibiricus barberi, an introduced ground squirrel in the Forest of Sénart (near Paris, France) was highly infested by I. ricinus, and consequently infected by B. burgdorferi sl. An index of the contribution of chipmunks to the density of infected questing nymphs on the vegetation (i.e., the acarological risk for humans) was compared to that of bank voles (Myodes glareolus) and of wood mice (Apodemus sylvaticus), two known native and sympatric competent reservoir hosts. Chipmunks produced nearly 8.5 times more infected questing nymphs than voles and mice. Furthermore, they contribute to a higher diversity of B. burgdorferi sl genospecies (B. afzelii, B. burgdorferi sensu stricto and B. garinii). The contribution of chipmunks varied between years and seasons, according to tick availability. As T. s. barberi must be a competent reservoir, it should amplify B. burgdorferi sl infection, hence increasing the risk of Lyme borreliosis in humans.
authors: INRA, UR346 Epidémiologie Animale, Saint Genès Champanelle, France.
authors: Maud
authors: M
authors: Marsot
authors: Jean-Louis
authors: JL
authors: Chapuis
authors: Patrick
authors: P
authors: Gasqui
authors: Anne
authors: A
authors: Dozières
authors: Sébastien
authors: S
authors: Masséglia
authors: Benoit
authors: B
authors: Pisanu
authors: Elisabeth
authors: E
authors: Ferquel
authors: Gwenaël
authors: G
authors: Vourc'h
mesh_terms: D000818:Animals; D003411:Arvicolinae / Q000382:microbiology; D025065:Borrelia burgdorferi / Q000235:genetics*; D017931:DNA Primers / Q000235:genetics; D004197:Disease Reservoirs / Q000382:microbiology* / Q000469:parasitology; D005602:France / Q000453:epidemiology; D058865:Introduced Species; D018884:Ixodes / Q000382:microbiology*; D008193:Lyme Disease / Q000453:epidemiology* / Q000382:microbiology / Q000635:transmission*; D051379:Mice; D051189:Murinae / Q000382:microbiology; D016133:Polymerase Chain Reaction; D011156:Population Density; D015995:Prevalence; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D012589:Sciuridae / Q000382:microbiology* / Q000469:parasitology; D013984:Tick Infestations / Q000453:epidemiology / Q000662:veterinary*
chemical_list: D017931:DNA Primers; D012336:RNA, Ribosomal, 16S
references: Appl Environ Microbiol. 2009 Aug;75(16):5410-6
references: 19542332
references: Parasitology. 1999 Jan;118 ( Pt 1):33-42
references: 10070659
references: Am J Epidemiol. 1989 Jul;130(1):143-50
references: 2787105
references: Int J Parasitol. 2010 Sep;40(11):1277-83
references: 20406644
references: Emerg Infect Dis. 2002 Dec;8(12):1468-73
references: 12498665
references: Trends Parasitol. 2003 Aug;19(8):370-5
references: 12901939
references: Science. 2000 Jan 21;287(5452):443-9
references: 10642539
references: Parasitol Res. 1990;76(6):540-4
references: 2381897
references: Ecology. 2009 Aug;90(8):2047-56
references: 19739367
references: Vector Borne Zoonotic Dis. 2008 Oct;8(5):645-52
references: 18454596
references: Trends Ecol Evol. 2009 Dec;24(12):686-93
references: 19712994
references: Euro Surveill. 2011 Jul 07;16(27):
references: 21794218
references: Proc Biol Sci. 2008 Jan 22;275(1631):227-35
references: 18029304
references: J Clin Microbiol. 1989 Aug;27(8):1723-7
references: 2768461
references: Proc Biol Sci. 2011 Jan 22;278(1703):239-46
references: 20685711
references: J Clin Microbiol. 1992 Nov;30(11):2830-4
references: 1280643
references: J Wildl Dis. 1993 Oct;29(4):527-32
references: 8258849
references: Conserv Biol. 2009 Oct;23(5):1204-13
references: 19459897
references: Appl Environ Microbiol. 2003 May;69(5):2825-30
references: 12732554
references: Parasite. 2008 Mar;15(1):35-43
references: 18416245
references: Ecology. 2009 Oct;90(10):2676-82
references: 19886477
references: Acta Trop. 1998 Jun;69(3):213-27
references: 9638274
references: Proc Natl Acad Sci U S A. 2004 Dec 28;101(52):18159-64
references: 15608069
references: Parasitology. 2012 Jun;139(7):847-63
references: 22336330
references: J Avian Med Surg. 2009 Mar;23(1):53-63
references: 19530408
references: Biometrics. 1983 Dec;39(4):1035-49
references: 6671118
references: Parasitology. 2004;129 Suppl:S37-65
references: 15938504
references: J Med Entomol. 1999 Nov;36(6):749-57
references: 10593076
references: Exp Appl Acarol. 1997 Dec;21(12):755-71
references: 9423270
references: Oecologia. 1968 Jun;1(3):219-235
references: 28306854
references: Parasitology. 2003 Jan;126(Pt 1):11-20
references: 12613759
references: J Med Entomol. 1995 Jul;32(4):433-8
references: 7650703
references: Ecol Lett. 2006 Apr;9(4):485-98
references: 16623733
references: Am Nat. 2008 Jun;171(6):743-54
references: 18462128
references: Appl Environ Microbiol. 2011 Aug 15;77(16):5716-21
references: 21705536
references: Folia Parasitol (Praha). 1995;42(1):73-80
references: 9599431
references: Zentralbl Bakteriol. 1998 Mar;287(3):196-204
references: 9580423
references: Int J Syst Bacteriol. 1994 Oct;44(4):743-52
references: 7981102
references: Vector Borne Zoonotic Dis. 2007 Winter;7(4):637-41
references: 18021026
references: Euro Surveill. 2006 Jun 22;11(6):E060622.1
references: 16819127
references: Appl Environ Microbiol. 1998 Apr;64(4):1169-74
references: 9546150
references: J Med Entomol. 1995 Nov;32(6):765-77
references: 8551498