title: [Mixed states].
abstract: The issue of mixed states has an important place in the debate on psychiatric nosography since the end of 19th century. The current definition of mixed states according to the DSM- IV, as a thymic episode of bipolar disorder type I, is probably somewhat too restrictive in clinical practice. Due to the clinical heterogeneity of bipolar disorder, the mixed states will define within a dimensional approach, likely in the next DSM- V. As the evolution, the prognosis or the therapeutic strategies differ from what is applied in other thymic episodes, this transition from "mixed state" to manic or depressive episodes "with mixed features" may be relevant in practice.
authors: CHU Clermont- Ferrand, BP 69, Clermont- Ferrand cedex 01, France. pmllorca@chu-clermontferrand.fr
authors: Pierre-Michel
authors: PM
authors: Llorca
authors: Thomas
authors: T
authors: Charpeaud
authors: Ludovic
authors: L
authors: Samalin
mesh_terms: D000339:Affect; D001143:Arousal; D001288:Attention; D001714:Bipolar Disorder / Q000145:classification / Q000175:diagnosis* / Q000523:psychology* / Q000628:therapy; D003072:Cognition Disorders / Q000145:classification / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D015897:Comorbidity; D003527:Cyclothymic Disorder / Q000145:classification / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D003937:Diagnosis, Differential; D039721:Diagnostic and Statistical Manual of Mental Disorders; D006801:Humans; D011379:Prognosis; D011596:Psychomotor Disorders / Q000145:classification / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D059020:Suicidal Ideation