title: Monocytosis has adverse prognostic significance and impacts survival in patients with T-cell lymphomas.
abstract: In this retrospective study we evaluated the prognostic impact of peripheral blood monocytosis in patients with T-cell non Hodgkin lymphomas with "aggressive-typically nodal presentation". In this dataset monocytes >0.8 × 10(9)/L had a strong and statistically significant negative impact on overall survival (OS). In univariate analysis several parameters, including age >60 years, advanced stage, bone marrow involvement, ECOG PS >1, high LDH level, monocytes >0.8 × 10(9)/L, hemoglobin<120 g/L, albumin<35 g/L) had a negative influence on outcome, but in multivariate analysis, monocytosis alone had a stronger association with poor OS.
authors: Department of Diagnostic, Clinical and Public Health Medicine, University of Modena and Reggio Emilia, Modena, Italy.
authors: Alessia
authors: A
authors: Bari
authors: Tamar
authors: T
authors: Tadmor
authors: Stefano
authors: S
authors: Sacchi
authors: Luigi
authors: L
authors: Marcheselli
authors: Eliana Valentina
authors: EV
authors: Liardo
authors: Samantha
authors: S
authors: Pozzi
authors: Stefano
authors: S
authors: Luminari
authors: Luca
authors: L
authors: Baldini
authors: Sandra
authors: S
authors: Marmiroli
authors: Massimo
authors: M
authors: Federico
authors: Aaron
authors: A
authors: Polliack
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007964:Leukocytosis / Q000175:diagnosis* / Q000209:etiology; D016399:Lymphoma, T-Cell / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000473:pathology*; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis; D055815:Young Adult