title: Where statistics and molecular microarray experiments biology meet.
abstract: This review chapter presents a statistical point of view to microarray experiments with the purpose of understanding the apparent contradictions that often appear in relation to their results. We give a brief introduction of molecular biology for nonspecialists. We describe microarray experiments from their construction and the biological principles the experiments rely on, to data acquisition and analysis. The role of epidemiological approaches and sample size considerations are also discussed.
authors: Instituto de Cálculo, Ciudad Universitaria, Buenos Aires, Argentina. dkelman@ic.fcen.uba.ar
authors: Diana M
authors: DM
authors: Kelmansky
mesh_terms: D000465:Algorithms; D001483:Base Sequence; D002138:Calibration; D055028:Comparative Genomic Hybridization; D003627:Data Interpretation, Statistical; D020869:Gene Expression Profiling / Q000379:methods*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D020411:Oligonucleotide Array Sequence Analysis / Q000379:methods