title: A comparison of pathologic outcomes of matched robotic and open partial nephrectomies.
abstract: OBJECTIVE
  Open partial nephrectomy (OPN) and robotic partial nephrectomy (RPN) are widely utilized techniques for small renal masses. The lack of tactile feedback and limitations of laparoscopy may result in differences in the surgical specimen that may impact oncologic outcome. We present postoperative pathological outcomes data in a cohort of patients matched for nephrometry score, tumor size, gender and age.
  
  
  METHODS
  We reviewed 81 patients who underwent partial nephrectomy between January 2003 and March 2010. Twenty-seven underwent RPN and 54 received OPN. Two OPN cases were matched for nephrometry score, tumor size, gender and age for each RPN. Postoperative pathological specimens were reviewed by a urologic pathologist regarding margin status, pathologic stage, histology, renal capsule violation, among other variables.
  
  
  RESULTS
  Sixty-two (76.5 %) patients were found to have renal cell carcinoma on final pathology. Frozen sectioning with tumor bed sampling was intra-operatively employed in 70 cases (86.4 %). The overall positive margin occurrence was 1 of 81 patients, which occurred during an RPN for a hilar tumor and converted to radical nephrectomy to achieve negative clinical margins. Additionally, 14.8 % of OPN patients had renal capsule violation as compared to 3.7 % of RPN cases (p = 0.34). Importantly, the mean distance to the proximal margin edge for RPN specimens (2.77 mm) was equivalent to OPN (3.01 mm), p = 0.46.
  
  
  CONCLUSIONS
  When matched for nephrometry score, tumor size, gender and age, RPN produces similar pathological outcomes to OPN.
authors: Department of Urology, Indiana University School of Medicine, 535 Barnhill Drive, Suite 420, Indianapolis, IN 46202, USA. mjmellon@iupui.edu
authors: Matthew J
authors: MJ
authors: Mellon
authors: Steven M
authors: SM
authors: Lucas
authors: Jennifer B J
authors: JB
authors: Kum
authors: Liang
authors: L
authors: Cheng
authors: Chandru
authors: C
authors: Sundaram
mesh_terms: D002292:Carcinoma, Renal Cell / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D012189:Retrospective Studies; D012371:Robotics; D016896:Treatment Outcome
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