title: Rupture during the endovascular treatment of intracranial aneurysms: outcomes and technical aspects.
abstract: OBJECTIVE
  The purpose of this study was to determine the incidence and outcomes of intraprocedural rupture (IPR) during endovascular coil embolization of intracranial aneurysm at a single center and to explore the technical reasons and put forward corresponding preventive measures for the feared event to serve as references for other endovascular specialists.
  
  
  METHODS
  The aneurysm database in our series was retrospectively reviewed. From April 2005 to March 2009, 176 aneurysms were consecutively treated with coils in 161 patients and IPR occurred in 12 patients. The medical records for the 12 patients were seriously examined.
  
  
  RESULTS
  Of the 12 patients (6.8 %), four were men and eight were women with a median age of 56 years. An emergency "rescue clipping" of the lesion was carried out in two patients, parent artery occlusion was performed in two cases, endovascular treatment was terminated in one case and aneurysm coiling was rapidly completed in the remaining seven cases. Complete occlusion was achieved in nine aneurysms and incomplete occlusion in one. One patient died, yielding a mortality rate of 8.3 %. The follow-up duration was 6-30 months (median 14 months) and the mean Glasgow Outcome Scale score at the last follow-up examination was 4.3.
  
  
  CONCLUSIONS
  The rate of IPR during endovascular coiling of intracranial aneurysms is quite low and the clinical outcome from this complication need not be catastrophic if managed appropriately. Improved operation skill and practical experience exchange among neuroradiologists are essential to lower the incidence or better patient prognoses.
authors: The 1st Department of Neurology, TCM Hospital of Guangdong Province, No. 111 Dade Road, Yuexiu District, Guangzhou, China, 510120. zhangyingmei1111@126.com
authors: Yingguang
authors: Y
authors: Zhang
authors: Guifu
authors: G
authors: Li
authors: Yefeng
authors: Y
authors: Cai
authors: Jixiang
authors: J
authors: Zhu
authors: Shengping
authors: S
authors: Huang
authors: Tielin
authors: T
authors: Li
authors: Wenyan
authors: W
authors: Zhu
authors: Jianfeng
authors: J
authors: Xu
mesh_terms: D000328:Adult; D000368:Aged; D017542:Aneurysm, Ruptured / Q000209:etiology / Q000628:therapy*; D002536:Cerebral Arteries / Q000601:surgery; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality / Q000517:prevention & control; D012189:Retrospective Studies; D013525:Surgical Instruments; D016896:Treatment Outcome