title: Breaking down the barriers to hepatitis C virus (HCV) treatment among individuals with HCV/HIV coinfection: action required at the system, provider, and patient levels.
abstract: The majority of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) coinfection occurs among persons who inject drugs. Rapid improvements in responses to HCV therapy have been observed, but liver-related morbidity rates remain high, given notoriously low uptake of HCV treatment. Advances in HCV therapy will have a limited impact on the burden of HCV-related disease at the population-level unless barriers to HCV education, screening, evaluation, and treatment are addressed and treatment uptake increases. This review will outline barriers to HCV care in HCV/HIV coinfection, with a particular emphasis on persons who inject drugs, proposing strategies to enhance HCV treatment uptake and outcomes.
authors: The Kirby Institute, University of New South Wales, Sydney, Australia. jgrebely@kirby.unsw.edu.au
authors: Jason
authors: J
authors: Grebely
authors: Megan
authors: M
authors: Oser
authors: Lynn E
authors: LE
authors: Taylor
authors: Gregory J
authors: GJ
authors: Dore
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D060085:Coinfection / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control; D006526:Hepatitis C / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control; D006801:Humans; D017053:Infection Control / Q000379:methods; D015819:Substance Abuse, Intravenous / Q000150:complications
chemical_list: D000998:Antiviral Agents
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