title: Parallel imaging acceleration of EPIK for reduced image distortions in fMRI.
abstract: EPI with Keyhole (EPIK) is a hybrid imaging technique used to improve the performance of EPI in dynamic MRI applications. The method had been previously validated at 1.5 T with both phantom and in vivo images; EPIK was able to provide a higher temporal resolution and less image distortions than single-shot EPI. The data presented here demonstrate that the performance of EPIK can be further improved by accelerating it with the parallel imaging. For this work, this combination was tested at 3 T. After initial evaluation using phantom images, use of the method in functional MRI was verified with visual fMRI measurements as well as MRI simulation results. The results showed that accelerated EPIK had increased temporal resolution with favorable robustness against susceptibility artifacts when compared with EPI or non-accelerated EPIK.
authors: Institute of Neuroscience and Medicine 4, Medical Imaging Physics, Forschungszentrum Jülich GmbH, Jülich, Germany.
authors: Seong Dae
authors: SD
authors: Yun
authors: Martina
authors: M
authors: Reske
authors: Kaveh
authors: K
authors: Vahedipour
authors: Tracy
authors: T
authors: Warbrick
authors: N Jon
authors: NJ
authors: Shah
mesh_terms: D001921:Brain / Q000033:anatomy & histology / Q000502:physiology; D003198:Computer Simulation; D017352:Echo-Planar Imaging / Q000379:methods* / Q000706:statistics & numerical data; D006185:Habituation, Psychophysiologic; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000706:statistics & numerical data; D015233:Models, Statistical; D019047:Phantoms, Imaging; D012044:Regression Analysis; D059629:Signal-To-Noise Ratio