title: Immune thrombocytopenic purpura in a child with thyroid hormone resistance - a rare presentation.
abstract: Resistance to thyroid hormone (RTH) is a rare entity characterized by a decreased target tissue responsiveness of thyroid hormones. Although immune thrombocytopenic purpura (ITP) has been reported with different thyroid disorders in the literature, its coexistence with RTH is not known. A 9-year-old girl presented with ITP and features of hypothyroidism in the form of goiter and growth retardation. She was subsequently found to have RTH. High-dose thyroid hormone replacement was required to overcome the resistance that not only ameliorated the features of hypothyroidism but also brought an apparent remission of ITP.
authors: Department of Pediatric Medicine, SSKM Hospital, Kolkata, West Bengal, India. sumantra.com@gmail.com
authors: Sumantra
authors: S
authors: Sarkar
authors: Rakesh
authors: R
authors: Mondal
authors: Madhumita
authors: M
authors: Nandi
authors: Jagabandhu
authors: J
authors: Ghosh
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications / Q000175:diagnosis*; D035583:Rare Diseases / Q000175:diagnosis; D018382:Thyroid Hormone Resistance Syndrome / Q000150:complications / Q000175:diagnosis*