title: Effectiveness of hand hygiene for removal of Clostridium difficile spores from hands.
abstract: This study determined whether surrogate organisms can predict activity against Clostridium difficile spores and compared the efficacy of hand hygiene preparations against C. difficile. Our data suggest that surrogate organisms were not predictive of C. difficile spore removal. Four preparations were significantly more effective than tap water at removing C. difficile.
authors: Research and Development, GOJO Industries, Akron, Ohio, USA. edmondss@gojo.com
authors: Sarah L
authors: SL
authors: Edmonds
authors: Carrie
authors: C
authors: Zapka
authors: Douglas
authors: D
authors: Kasper
authors: Robert
authors: R
authors: Gerber
authors: Robert
authors: R
authors: McCormack
authors: David
authors: D
authors: Macinga
authors: Stuart
authors: S
authors: Johnson
authors: Susan
authors: S
authors: Sambol
authors: Christopher
authors: C
authors: Fricker
authors: James
authors: J
authors: Arbogast
authors: Dale N
authors: DN
authors: Gerding
mesh_terms: D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D001407:Bacillus / Q000187:drug effects*; D002710:Chlorhexidine / Q000031:analogs & derivatives / Q000494:pharmacology; D016360:Clostridioides difficile / Q000187:drug effects*; D006235:Hand Disinfection; D006801:Humans; D006861:Hydrogen Peroxide / Q000494:pharmacology; D010463:Peracetic Acid / Q000494:pharmacology; D011237:Predictive Value of Tests; D012915:Soaps / Q000494:pharmacology; D012973:Sodium Hypochlorite / Q000494:pharmacology; D013171:Spores, Bacterial / Q000187:drug effects; D014260:Triclosan / Q000494:pharmacology; D014867:Water / Q000494:pharmacology
chemical_list: D000891:Anti-Infective Agents, Local; D012915:Soaps; D014867:Water; D014260:Triclosan; D006861:Hydrogen Peroxide; D012973:Sodium Hypochlorite; D010463:Peracetic Acid; C010882:chlorhexidine gluconate; D002710:Chlorhexidine