title: Iodide-catalyzed halocyclization/cycloaddition/elimination cascade reaction.
abstract: An iodocyclization reaction of o-alkynylphenyl carboxaldehydes is reported that is truly catalytic with respect to the electrophilic iodine source. With a combination of tetrabutylammonium iodide (TBAI), Oxone as non-nucleophilic and easy to handle co-oxidant, and fluorinated protic solvents, highly substituted 1-naphthalenones could be prepared in high yields of up to 91%.
authors: Institute of Organic Chemistry, Eberhard Karls University Tuebingen, Auf der Morgenstelle 18, D-72076 Tuebingen, Germany.
authors: Ulrich
authors: U
authors: Kloeckner
authors: Peter
authors: P
authors: Finkbeiner
authors: Boris J
authors: BJ
authors: Nachtsheim