title: Fabrication of Cr doped SnO2 nanoparticles based biosensor for the selective determination of riboflavin in pharmaceuticals.
abstract: We report the fabrication and testing of a riboflavin (RF) biosensor based on the use of Cr doped SnO2 nanoparticles. The Cr-SnO2 nanoparticles with chromium concentration from 0 to 5 wt% were synthesised by a microwave irradiation method. Magnetic studies revealed that only 3 wt% Cr doped nano-SnO2 has ferromagnetic behaviour at room temperature. This Cr-SnO2 nanoparticles modified electrode responded to RF linearly over a concentration range of 0.2 × 10(-6) to 1.0 × 10(-4) M with a detection limit of 107 nM. The fabricated sensor showed an excellent anti-interference ability against electroactive species and metal ions and proved to be useful for the estimation of the RF content in pharmaceutical samples with satisfactory recovery.
authors: Department of Bioelectronics and Biosensors, Alagappa University, Karaikudi-630003, Tamilnadu, India.
authors: N
authors: N
authors: Lavanya
authors: S
authors: S
authors: Radhakrishnan
authors: C
authors: C
authors: Sekar
authors: M
authors: M
authors: Navaneethan
authors: Y
authors: Y
authors: Hayakawa
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D002857:Chromium / Q000737:chemistry*; D057230:Limit of Detection; D053768:Metal Nanoparticles; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D012256:Riboflavin / Q000032:analysis*; D017971:Tin Compounds / Q000737:chemistry*
chemical_list: D004364:Pharmaceutical Preparations; D017971:Tin Compounds; D002857:Chromium; C045358:stannic oxide; D012256:Riboflavin