title: [Antiproliferative activity of diclofenac at tumor cell cultures].
abstract: It is known that for risk group's importance of early diagnostics and prevention of a cancer of a thick section of the intestines. The view was expressed that the use of nonsteroidal anti-inflammatory drugs prospectively. The article presents the data obtained after the determination of the effect on the domestic drug diclofenac on the ability of the lines of tumor cells of the human colon multiply this antiproliferativoe action on the dose of the drug. Used photometric method for determination antiproliferativoe action. In vitro determined the effect of the national drug diclofenac on the ability of the lines of tumor cells of the human colon multiply, and is set in a dose-dependent effect. It is established that under the action of NSAIDS metabolic activity of cells can both strengthen and weaken that depends on the line of tumor cells and the concentration of the drug.
authors: A V
authors: AV
authors: Smirnova
authors: L B
authors: LB
authors: Lazebnik
authors: I E
authors: IE
authors: Trubitsina
authors: E V
authors: EV
authors: Tkachenko
authors: G G
authors: GG
authors: Varvarina
authors: V N
authors: VN
authors: Drozdov
authors: V A
authors: VA
authors: Kim
authors: A Iu
authors: AIu
authors: Baryshnikova
authors: Z A
authors: ZA
authors: Sokolova
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects*; D003110:Colonic Neoplasms / Q000378:metabolism* / Q000473:pathology; D004008:Diclofenac / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006801:Humans
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac