title: Silver-mediated trifluoromethylation-iodination of arynes.
abstract: An unprecedented silver-mediated vicinal trifluoromethylation-iodination of arynes that quickly introduces CF(3) and I groups onto aromatic rings in a single step to give o-trifluoromethyl iodoarenes has been developed. A new reactivity of AgCF(3) has been revealed, and 2,2,6,6-tetramethylpiperidine plays an important role in this difunctionalization reaction.
authors: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Ling-Ling Road, Shanghai 200032, China.
authors: Yuwen
authors: Y
authors: Zeng
authors: Laijun
authors: L
authors: Zhang
authors: Yanchuan
authors: Y
authors: Zhao
authors: Chuanfa
authors: C
authors: Ni
authors: Jingwei
authors: J
authors: Zhao
authors: Jinbo
authors: J
authors: Hu
mesh_terms: D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry*; D008745:Methylation; D012834:Silver / Q000737:chemistry*
chemical_list: D006845:Hydrocarbons, Fluorinated; D012834:Silver; D007455:Iodine