title: Hypersensitivity reaction probably induced by sugammadex.
abstract: We report here an intellectually compromised 7-year-old boy with cerebral palsy who developed a hypersensitivity reaction several minutes after the administration of sugammadex for subsequent extubation. He developed signs of upper airway stenosis and decreased oxygen saturation, as well as wheals on his neck, chest, and both upper extremities. He was successfully treated with immediate administration of adrenaline and hydrocortisone. A hypersensitivity reaction to sugammadex was suspected on the basis of the patient's clinical course.
authors: Department of Dentistry, Morinomiya Hospital, Osaka City, Japan. asahi@omichikai.or.jp
authors: Yoshinao
authors: Y
authors: Asahi
authors: Shiro
authors: S
authors: Omichi
authors: Seita
authors: S
authors: Adachi
authors: Hajime
authors: H
authors: Kagamiuchi
authors: Junichiro
authors: J
authors: Kotani
mesh_terms: D000732:Androstanols / Q000037:antagonists & inhibitors*; D002648:Child; D004342:Drug Hypersensitivity / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008297:Male; D003473:Neuromuscular Nondepolarizing Agents / Q000037:antagonists & inhibitors*; D000077123:Rocuronium; D000077122:Sugammadex; D047408:gamma-Cyclodextrins / Q000009:adverse effects*
chemical_list: D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D047408:gamma-Cyclodextrins; D000077122:Sugammadex; D000077123:Rocuronium