title: Longitudinal surveillance for meningitis by Acinetobacter in a large urban setting in Brazil.
abstract: The study aim was to describe the emergence of carbapenem resistance and clonal complexes (CC), defined by multilocus sequence typing (MLST), in Acinetobacter baumannii in a surveillance system for meningitis. Starting in 1996 in an urban setting of Brazil, surveillance detected meningitis by Acinetobacter sp for the first time in 2002. Up to 2008, 35 isolates were saved. Carbapenem resistance emerged in 2006, reaching 70% of A. baumannii isolates in 2008, including one that was colistin resistant. A. baumannii belonged to CC113/79 (University of Oxford/Institute Pasteur schemes), CC235/162 and CC103/15. Dissemination of infections resistant to all antimicrobial agents may occur in the future.
authors: Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
authors: T
authors: T
authors: Coelho-Souza
authors: J N
authors: JN
authors: Reis
authors: N
authors: N
authors: Martins
authors: I S
authors: IS
authors: Martins
authors: A O
authors: AO
authors: Menezes
authors: M G
authors: MG
authors: Reis
authors: N O
authors: NO
authors: Silva
authors: R C S
authors: RC
authors: Dias
authors: L W
authors: LW
authors: Riley
authors: B M
authors: BM
authors: Moreira
mesh_terms: D000151:Acinetobacter Infections / Q000453:epidemiology* / Q000382:microbiology; D040981:Acinetobacter baumannii / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001938:Brazil / Q000453:epidemiology; D015780:Carbapenems / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D003091:Colistin / Q000494:pharmacology; D024901:Drug Resistance, Multiple, Bacterial; D062665:Epidemiological Monitoring; D005260:Female; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000453:epidemiology* / Q000382:microbiology; D008875:Middle Aged; D017720:Molecular Epidemiology; D058885:Multilocus Sequence Typing; D014505:Urban Population; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D015780:Carbapenems; D003091:Colistin
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