title: Bone turnover markers in primary hyperparathyroidism.
abstract: Primary hyperparathyroidism is an endocrine disorder characterized by elevated or inappropriate normal levels of parathyroid hormone in a setting of hypercalcemia. The inclusion of calcium on the basic metabolic bone panel has allowed this disorder to be diagnosed even in the absence of symptoms. Nevertheless, the skeleton can be a target of excess parathyroid hormone activity even during its asymptomatic presentation. Bone turnover markers a surrogate index of the process of the remodeling process at the level of bone, and thus can be useful to monitor skeleton involvement in primary hyperparathyroidism.
authors: Metabolic Bone Diseases Unit, Division of Endocrinology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.
authors: Aline G
authors: AG
authors: Costa
authors: John P
authors: JP
authors: Bilezikian
mesh_terms: D016723:Bone Remodeling / Q000502:physiology*; D001842:Bone and Bones / Q000378:metabolism; D057966:Calcimimetic Agents / Q000627:therapeutic use; D004164:Diphosphonates / Q000627:therapeutic use; D004967:Estrogens / Q000627:therapeutic use; D006801:Humans; D006934:Hypercalcemia; D049950:Hyperparathyroidism, Primary / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D016105:Parathyroidectomy; D020845:Selective Estrogen Receptor Modulators / Q000627:therapeutic use
chemical_list: D057966:Calcimimetic Agents; D004164:Diphosphonates; D004967:Estrogens; D020845:Selective Estrogen Receptor Modulators
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