title: [Clinical and biological prognostic factors in 135 patients affected by sinonasal carcinoma treated in Piedmont].
abstract: Clinical and biological prognostic factors in 135 patients affected by sinonasal carcinoma treated in Piedmont. Long-term survival of patients with sinonasal carcinoma remains disappointing in spite of aggressive treatment. The aim of the study is the assessment of overall survival in a group of patients treated with a fixed protocol and the positivity of proliferation and neoangiogenesis markers (Ki-67 and VEGF). From our data it comes out that staging, histological type and treatment are the most important clinical and pathological prognostic factors, moreover surgery +/- radiotherapy is the first line treatment for these tumors. Proliferation index and neoangiogenesis plays a pivotal role in the natural history of such neoplasms.
authors: Clinica ORL, Dipartimento di Fisiopatologia Clinica, Università degli Studi di Torino, Via Genova 3, 10126 Torino, Italy.
authors: L
authors: L
authors: Raimondo
authors: M
authors: M
authors: Garzaro
authors: N
authors: N
authors: Naqe
authors: F
authors: F
authors: Zanardi
authors: A
authors: A
authors: Lauria
authors: G
authors: G
authors: Pecorari
authors: C
authors: C
authors: Giordano
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality* / Q000628:therapy; D005260:Female; D006258:Head and Neck Neoplasms / Q000401:mortality* / Q000628:therapy; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D010255:Paranasal Sinus Neoplasms / Q000401:mortality* / Q000628:therapy; D011379:Prognosis; D000077195:Squamous Cell Carcinoma of Head and Neck; D015996:Survival Rate; D055815:Young Adult