title: Phylogenomic clustering for selecting non-redundant genomes for comparative genomics.
abstract: BACKGROUND
  Analyses in comparative genomics often require non-redundant genome datasets. Eliminating redundancy is not as simple as keeping one strain for each named species because genomes might be redundant at a higher taxonomic level than that of species for some analyses; some strains with different species names can be as similar as most strains sharing a species name, whereas some strains sharing a species name can be so different that they should be put into different groups; and some genomes lack a species name.
  
  
  RESULTS
  We have implemented a method and Web server that clusters a genome dataset into groups of redundant genomes at different thresholds based on a few phylogenomic distance measures.
  
  
  BACKGROUND
  The Web interface, similarity and distance data and R-scripts can be accessed at http://microbiome.wlu.ca/research/redundancy/.
authors: Department of Biology and Department of Mathematics, Wilfrid Laurier University, Waterloo, ON N2L 3C5, Canada. gmoreno@wlu.ca
authors: Gabriel
authors: G
authors: Moreno-Hagelsieb
authors: Zilin
authors: Z
authors: Wang
authors: Stephanie
authors: S
authors: Walsh
authors: Aisha
authors: A
authors: ElSherbiny
mesh_terms: D016678:Genome; D023281:Genomics / Q000379:methods*; D020407:Internet; D010802:Phylogeny; D012984:Software