title: Pediatric case report on magnetic resonance imaging/transrectal ultrasound-fusion biopsy of rhabdomyosarcoma of the bladder/prostate: a new tool to reduce therapy-associated morbidity?
abstract: Rhabdomyosarcomas are the most common soft tissue sarcomas in children. Here we present management of an 18-month-old boy with metastatic rhabdomyosarcoma of the bladder/prostate. After radiochemotherapy, high-spatial-resolution 3-Tesla multiparametric magnetic resonance imaging (MRI) showed regressive systemic disease but a residual mass at the right seminal vesicle. For histologic re-evaluation, 3-dimensional-controlled stereotactic MRI/transrectal ultrasound (TRUS)-fusion biopsy specimens were taken. Because histologic analysis showed nonvital tissue, a decision could be made against adjuvant radical cystoprostatectomy. Advanced 3-Tesla imaging and MRI/TRUS-fusion biopsies in children are feasible and represent an effective tool to examine suspicious pelvic lesions. Depending on histology, this can lead to a significant reduction of therapy-associated morbidity.
authors: Department of Urology, UniversityHospital Heidelberg, Heidelberg, Germany.
authors: Timur H
authors: TH
authors: Kuru
authors: Matthias C
authors: MC
authors: Roethke
authors: Joanne
authors: J
authors: Nyarangi-Dix
authors: Stella
authors: S
authors: Okouoyo
authors: Clemens
authors: C
authors: Stockklausner
authors: Jens-Peter
authors: JP
authors: Schenk
authors: Jürgen
authors: J
authors: Debus
authors: Wilfried
authors: W
authors: Roth
authors: Dogu
authors: D
authors: Teber
authors: Sascha
authors: S
authors: Pahernik
authors: Heinz-Peter
authors: HP
authors: Schlemmer
authors: Markus
authors: M
authors: Hohenfellner
authors: Boris A
authors: BA
authors: Hadaschik
mesh_terms: D059248:Chemoradiotherapy; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D019160:Endosonography; D006801:Humans; D007223:Infant; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging; D008297:Male; D010347:Patient Care Planning; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D012208:Rhabdomyosarcoma / Q000175:diagnosis* / Q000556:secondary / Q000628:therapy; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000628:therapy