title: The natural course of abdominal aortic aneurysms that meet the treatment criteria but not the operative requirements.
abstract: BACKGROUND
  Abdominal aortic aneurysms (AAAs) of 55 mm diameter or growth >5 mm in 6 months are commonly accepted treatment criteria. The aim of this study was to establish the outcome of aneurysms that met the treatment criteria but not the operative requirements.
  
  
  METHODS
  Patients (n = 154) who were declined from operative care of AAA in Helsinki University Central Hospital (HUCH) during 2000-2010 were retrospectively analysed. Reasons for exclusion were identified. The follow-up period extended until the end of April 2012. The rupture rate and mortality were determined. The patients were analysed according to the aneurysm diameter: 55-60, 61-70 and >70 mm.
  
  
  RESULTS
  The reasons for exclusion from operative treatment were cardiorespiratory co-morbidities in 33%, cancer in 8%, overall condition in 33% and patient's choice in 21% of the patients. Regardless of the size of the aneurysm, the cause of death was aneurysm rupture in 43%, which was confirmed either in hospital or in autopsy for 76% of the patients. Of the ruptured aneurysms, 12 were operated of which five survived.
  
  
  CONCLUSIONS
  A ruptured aneurysm is the most common cause of death among patients unfit for surgery; this should be considered in the preoperative evaluation process, especially since 5 of the 12 patients survived the ruptured AAA (RAAA) operation.
authors: Department of Vascular Surgery, Helsinki University Central Hospital (HUCH), P.O. Box 340, 00029 HUS Helsinki, Finland. katariina.noronen@hus.fi
authors: K
authors: K
authors: Noronen
authors: S
authors: S
authors: Laukontaus
authors: I
authors: I
authors: Kantonen
authors: M
authors: M
authors: Lepäntalo
authors: M
authors: M
authors: Venermo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000150:complications / Q000175:diagnosis / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D001019:Aortic Rupture / Q000209:etiology* / Q000401:mortality; D015897:Comorbidity; D018450:Disease Progression; D018572:Disease-Free Survival; D017558:Elective Surgical Procedures; D005260:Female; D005387:Finland; D006304:Health Status; D006785:Hospitals, University; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D016312:Treatment Refusal; D014656:Vascular Surgical Procedures / Q000009:adverse effects / Q000401:mortality