title: Retrovirus infected cells contain viral microRNAs.
abstract: The encoding of microRNAs in retroviral genomes has remained a controversial hypothesis despite significant supporting evidence in recent years. A recent publication demonstrating the production of functional miRNAs from the retrovirus bovine leukemia virus adds further credence to the fact that retroviruses do indeed encode their own miRNAs. Here we comment on the importance of this paper to the field, as well as examine the other known examples of miRNAs encoded by RNA viruses.
authors: Molecular Virology Section, Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, 9000 Rockville Pike, Bethesda, MD 20810, USA.
authors: Zachary A
authors: ZA
authors: Klase
authors: Gavin C
authors: GC
authors: Sampey
authors: Fatah
authors: F
authors: Kashanchi
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000378:metabolism*; D006801:Humans; D001909:Leukemia Virus, Bovine / Q000235:genetics*; D035683:MicroRNAs / Q000235:genetics*; D009369:Neoplasms / Q000235:genetics*
chemical_list: D035683:MicroRNAs
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