title: Recovering intrinsic fluorescence by Monte Carlo modeling.
abstract: We present a novel way to recover intrinsic fluorescence in turbid media based on Monte Carlo generated look-up tables and making use of a diffuse reflectance measurement taken at the same location. The method has been validated on various phantoms with known intrinsic fluorescence and is benchmarked against photon-migration methods. This new method combines more flexibility in the probe design with fast reconstruction and showed similar reconstruction accuracy as found in other reconstruction methods.
authors: Philips Research, Minimally Invasive Healthcare Department, High Tech Campus 34, 5656 AE Eindhoven, The Netherlands. manfred.mueller@philips.com
authors: Manfred
authors: M
authors: Müller
authors: Benno H W
authors: BH
authors: Hendriks
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D005260:Female; D005453:Fluorescence; D005456:Fluorescent Dyes; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008954:Models, Biological; D009010:Monte Carlo Method; D009391:Nephelometry and Turbidimetry; D055620:Optical Phenomena; D019047:Phantoms, Imaging; D012542:Scattering, Radiation; D013050:Spectrometry, Fluorescence / Q000706:statistics & numerical data
chemical_list: D005456:Fluorescent Dyes