title: Medical management and strategies to prevent coronary artery disease in patients with type 2 diabetes mellitus.
abstract: Coronary artery disease (CAD) in patients with type 2 diabetes mellitus (T2DM) is associated with increased immediate and long-term mortality compared with patients without T2DM. The amplified incidence of CAD stems partly from the aggregation of multiple risk factors, such as obesity, dyslipidemia, and hypertension, which occur in this population. In addition, there appear to be increased forces at play at the molecular and vascular levels in these individuals, which is evidenced by the increased thrombosis and inflammation that is seen in those with diabetic atherosclerosis. Hence, there is a growing need to emphasize early and vigilant risk factor management in patients with T2DM to help reduce their burden of cardiovascular-related mortality. In this article, we review the primary and secondary prevention measures as well as the management of CAD in patients with T2DM.
authors: Division of Endocrinology, University of Florida College of Medicine-Jacksonville, Jacksonville, FL 32209, USA. mae.sheikh-ali@jax.ufl.edu
authors: Mae
authors: M
authors: Sheikh-Ali
authors: Prafull
authors: P
authors: Raheja
authors: Nancy
authors: N
authors: Borja-Hart
mesh_terms: D003324:Coronary Artery Disease / Q000209:etiology / Q000517:prevention & control*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000188:drug therapy; D019468:Disease Management; D006801:Humans; D008403:Mass Screening / Q000379:methods*; D012307:Risk Factors; D055502:Secondary Prevention / Q000379:methods*