title: S-1-induced lung injury combined with pneumocystis pneumonia.
abstract: Pulmonary injuries due to S-1 have been reported, and these reports have shown an increase in lung cancer following the increased usage of S-1 in treating lung cancer. We report the first case of lung injury due to S-1 in combination with pneumocystis pneumonia (PCP), because the radiological findings and clinical courses were compatible with S-1-induced lung injury combined with PCP. We should consider that S-1 might induce lung injuries which might occur with PCP, especially with a history of drug-induced or radiation-induced lung injuries.
authors: National Hospital Organization Matsue Medical Center, Matsue, Japan. yano@matsue.hosp.go.jp
authors: Shuichi
authors: S
authors: Yano
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D004338:Drug Combinations; D006801:Humans; D055370:Lung Injury / Q000139:chemically induced / Q000150:complications / Q000175:diagnosis*; D008175:Lung Neoplasms / Q000188:drug therapy; D008297:Male; D010094:Oxonic Acid / Q000009:adverse effects*; D011020:Pneumonia, Pneumocystis / Q000150:complications / Q000175:diagnosis*; D005641:Tegafur / Q000009:adverse effects*
chemical_list: D000964:Antimetabolites, Antineoplastic; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid
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