title: Two cohort and three independent anonymous twin projects at the Keio Twin Research Center (KoTReC).
abstract: The Keio Twin Research Center has conducted two longitudinal twin cohort projects and has collected three independent and anonymous twin data sets for studies of phenotypes related to psychological, socio-economic, and mental health factors. The Keio Twin Study has examined adolescent and adult cohorts, with a total of over 2,400 pairs of twins and their parents. DNA samples are available for approximately 600 of these twin pairs. The Tokyo Twin Cohort Project has followed a total of 1,600 twin pairs from infancy to early childhood. The large-scale cross-sectional twin study (CROSS) has collected data from over 4,000 twin pairs, from 3 to 26 years of age, and from two high school twin cohorts containing a total of 1,000 pairs of twins. These data sets of anonymous twin studies have mainly targeted academic performance, attitude, and social environment. The present article introduces the research designs and major findings of our center, such as genetic structures of cognitive abilities, personality traits, and academic performances, developmental effects of genes and environment on attitude, socio-cognitive ability and parenting, genes x environment interaction on attitude and conduct problem, and statistical methodological challenges and so on. We discuss the challenges in conducting twin research in Japan.
authors: Faculty of Letters, Keio University, Tokyo, Japan. juko@msa.biglobe.ne.jp
authors: Juko
authors: J
authors: Ando
authors: Keiko K
authors: KK
authors: Fujisawa
authors: Chizuru
authors: C
authors: Shikishima
authors: Kai
authors: K
authors: Hiraishi
authors: Mari
authors: M
authors: Nozaki
authors: Shinji
authors: S
authors: Yamagata
authors: Yusuke
authors: Y
authors: Takahashi
authors: Koken
authors: K
authors: Ozaki
authors: Kunitake
authors: K
authors: Suzuki
authors: Minako
authors: M
authors: Deno
authors: Shoko
authors: S
authors: Sasaki
authors: Tatsushi
authors: T
authors: Toda
authors: Kazuhiro
authors: K
authors: Kobayashi
authors: Yutaro
authors: Y
authors: Sugimoto
authors: Mitsuhiro
authors: M
authors: Okada
authors: Nobuhiko
authors: N
authors: Kijima
authors: Yutaka
authors: Y
authors: Ono
authors: Kimio
authors: K
authors: Yoshimura
authors: Shinichiro
authors: S
authors: Kakihana
authors: Hiroko
authors: H
authors: Maekawa
authors: Toshimitsu
authors: T
authors: Kamakura
authors: Koichi
authors: K
authors: Nonaka
authors: Noriko
authors: N
authors: Kato
authors: Syuichi
authors: S
authors: Ooki
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004200:Diseases in Twins / Q000453:epidemiology / Q000235:genetics*; D005260:Female; D006801:Humans; D007223:Infant; D007558:Italy / Q000453:epidemiology; D008297:Male; D012042:Registries; D014429:Twins, Dizygotic / Q000235:genetics*; D014430:Twins, Monozygotic / Q000235:genetics*; D055815:Young Adult