title: Fabrication and aggregation of thermoresponsive glucose-functionalized double hydrophilic copolymers.
abstract: Novel double-hydrophilic thermosensitive statistical glycopolymers, poly(N-isopropylacrylamide-co-6-O-vinyladipoyl-D-glucose), were fabricated using a chemoenzymatic process and free radical copolymerization. The structures of the glycopolymers were confirmed by (1)H and (13)C NMR, and their molar mass distributions determined by gel permeation chromatography. UV-vis spectroscopy data showed that the polymers exhibited reproducible temperature-responsive behavior. The self-assembly and critical aggregation concentration was verified by fluorescence spectroscopy with pyrene acting as a hydrophobic probe. Measurements by laser light scattering and transmission electron microscopy revealed that the glycopolymers were able to self-assemble into aggregates with varying particle sizes and morphologies in aqueous solutions.
authors: College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, PR China.
authors: Shao-Feng
authors: SF
authors: Lou
authors: Hua
authors: H
authors: Zhang
authors: Gareth R
authors: GR
authors: Williams
authors: Christopher
authors: C
authors: Branford-White
authors: Hua-Li
authors: HL
authors: Nie
authors: Jing
authors: J
authors: Quan
authors: Li-Min
authors: LM
authors: Zhu
mesh_terms: D000178:Acrylamides / Q000737:chemistry; D002850:Chromatography, Gel; D005947:Glucose / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D057927:Hydrophobic and Hydrophilic Interactions; D009682:Magnetic Resonance Spectroscopy; D008823:Micelles; D011108:Polymers / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013549:Sweetening Agents / Q000494:pharmacology*; D013696:Temperature
chemical_list: D000178:Acrylamides; D008823:Micelles; D011108:Polymers; D013549:Sweetening Agents; C067295:N-isopropylacrylamide; D005947:Glucose