title: Percutaneous lung biopsy: comparison between an augmented reality CT navigation system and standard CT-guided technique.
abstract: OBJECTIVE
  Percutaneous lung biopsies (PLBs) performed for the evaluation of pulmonary masses require image guidance to avoid critical structures. A new CT navigation system (SIRIO, "Sistema robotizzato assistito per il puntamento intraoperatorio") for PLBs was validated.
  
  
  METHODS
  The local Institutional Review Board approved this retrospective study. Image-guided PLBs in 197 patients were performed with a CT navigation system (SIRIO). The procedures were reviewed based on the number of CT scans, patients' radiation exposure and procedural time recorded. Comparison was performed with a group of 72 patients undergoing standard CT-guided PLBs. Sensitivity, specificity and overall diagnostic accuracy were assessed in both groups.
  
  
  RESULTS
  SIRIO-guided PLBs showed a significant reduction in procedure time, number of required CT scans and the radiation dose administered to patients ([Formula: see text]). In terms of diagnostic accuracy, SIRIO proved to be more accurate for small-sized lesions ([Formula: see text]20 mm) than standard CT-guidance.
  
  
  CONCLUSIONS
  SIRIO proved to be a reliable and effective tool when performing CT-guided PLBs and was especially useful for sampling small ([Formula: see text]20 mm) lesions.
authors: Department of Radiology, University Campus Bio-Medico of Rome, Via Alvaro del Portillo 200, 00128 , Rome, Italy.
authors: R F
authors: RF
authors: Grasso
authors: E
authors: E
authors: Faiella
authors: G
authors: G
authors: Luppi
authors: E
authors: E
authors: Schena
authors: F
authors: F
authors: Giurazza
authors: R
authors: R
authors: Del Vescovo
authors: F
authors: F
authors: D'Agostino
authors: R L
authors: RL
authors: Cazzato
authors: B
authors: B
authors: Beomonte Zobel
mesh_terms: D000368:Aged; D004867:Equipment Design; D005260:Female; D005471:Fluoroscopy / Q000379:methods*; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods*; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D008171:Lung Diseases / Q000175:diagnosis*; D008175:Lung Neoplasms / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012372:ROC Curve; D015641:Radiography, Interventional / Q000295:instrumentation*; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000295:instrumentation*; D014584:User-Computer Interface
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