title: Quality of life and psychological distress of adult recipients after living donor liver transplantation.
abstract: This longitudinal prospective study evaluated health-related quality of life (HRQoL) and psychological distress among recipients after right-lobe adult-adult living donor liver transplantation (LDLT). We measured HRQoL among 81 consecutive recipients using the Chinese version of the Medical Outcomes Study Short Form-36 (SF-36). Psychological symptoms were measured using the Symptom Checklist-90-Revised (SCL-90-R). Clinical data were collected from Chinese Liver Transplant Registry records. Sixty-two recipients completed follow-up assessments at 6, 12, 24, and 36 months posttransplantation. SF-36 domain scores were lowest at 6 months, especially for role-physical, bodily pain, vitality, social functioning, role-emotional and mental component summary scale scores. They improved dramatically in the first year posttransplantation. None of the SF-36 domain scores differed significantly between 12 and 24 months. No SCL-90-R dimension score differed significantly among the four assessments (P > .05). Mental component summary scale scores significantly correlated with all four SCL-90-R global severity index scores (P < .05). HRQoL improved significantly in adult recipients in the first year after LDLT, but not thereafter. Patients recovered psychological well-being quickly after transplantation; this factor had an important influence on the HRQoL of LDLT recipients.
authors: West China Hospital, Chengdu, Sichuan, China. shgjin2003@yahoo.com.cn
authors: S
authors: S
authors: Jin
authors: B
authors: B
authors: Xiang
authors: L
authors: L
authors: Zhong
authors: L
authors: L
authors: Yan
authors: Z
authors: Z
authors: Chen
authors: W
authors: W
authors: Wang
authors: M
authors: M
authors: Xu
authors: J
authors: J
authors: Yang
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D017093:Liver Failure / Q000523:psychology* / Q000601:surgery; D016031:Liver Transplantation / Q000379:methods* / Q000523:psychology*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D011336:Probability; D011446:Prospective Studies; D011788:Quality of Life; D013315:Stress, Psychological; D013997:Time Factors; D016896:Treatment Outcome