title: Allergy: airway epithelial Rac1 suppresses allergic inflammation.
abstract: Loss of Rac1 in airway epithelial cells has demonstrated its participation in the ingestion of apoptotic cells and, more importantly, has revealed an unexpected role for Rac1 in maintaining the anti-inflammatory and non-immunogenic environment of the lung and reducing the intensity of allergic sensitization.
authors: Program in Cell Biology, Department of Pediatrics, National Jewish Health, 1400 Jackson St, Denver, CO 80206, USA. Hensonp@njhealth.org
authors: Peter M
authors: PM
authors: Henson
authors: Donna L
authors: DL
authors: Bratton
mesh_terms: D000818:Animals; D017209:Apoptosis; D004847:Epithelial Cells / Q000201:enzymology / Q000276:immunology*; D006801:Humans; D006967:Hypersensitivity / Q000201:enzymology*; D008168:Lung / Q000201:enzymology / Q000276:immunology*; D020545:Respiratory Mucosa / Q000201:enzymology / Q000276:immunology*; D020830:rac1 GTP-Binding Protein / Q000502:physiology*
chemical_list: D020830:rac1 GTP-Binding Protein