title: Irritable bowel syndrome--diarrhoea.
abstract: IBS is a functional gastrointestinal disorder which has been subtyped according to bowel habits. This review presents recommendations for IBS-D which makes up about 1/3 of all patients and which is defined as IBS with loose or watery stools with ≥25% of bowel movements. Because IBS is a complex biopsychosocial illness, treatment cannot and should not be directed only to altered bowel habits. Evidence will be presented for dietary manipulations, probiotics and pharmacotherapies including tricyclic agents, antibiotics, serotonin antagonists and anti-diarrhoeal agents in the management of patients with IBS-D.
authors: Division of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, 1685 Highland Avenue, Suite 4000, Madison, WI 53705, USA. axw@medicine.wisc.edu
authors: Arnold
authors: A
authors: Wald
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use; D000930:Antidiarrheals / Q000627:therapeutic use; D003248:Constipation / Q000209:etiology; D003672:Defecation; D003967:Diarrhea / Q000209:etiology / Q000628:therapy*; D004040:Dietary Carbohydrates / Q000009:adverse effects; D004043:Dietary Fiber / Q000627:therapeutic use; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000145:classification / Q000150:complications / Q000523:psychology / Q000628:therapy*; D008139:Loperamide / Q000627:therapeutic use; D019936:Probiotics / Q000627:therapeutic use; D012702:Serotonin Antagonists / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000929:Antidepressive Agents, Tricyclic; D000930:Antidiarrheals; D004040:Dietary Carbohydrates; D004043:Dietary Fiber; D012702:Serotonin Antagonists; D008139:Loperamide