title: [Protein C deficiency in patient with sepsis-associated disseminated intravascular coagulation and deep vein thrombosis].
abstract: Disseminate intravascular coagulation (DIC) is a clinical pathological syndrome associated to several diseases. Sepsis is the most common cause in infants and children. DIC results from the anomalous activation of blood coagulation, widespread formation of thrombi in the microcirculation, and consumption of clotting factors and platelets. Clinical findings are variable; the most common is bleeding, followed by purpura and acral gangrene (purpura fulminans). We report a patient with sepsis associated-DIC and concurrent deep venous thrombosis. The diagnostic evaluation allowed to discover inherited thrombophilia associated to protein C deficiency.
authors: Terapia Intensiva Pediátrica, Hospital Provincial de Neuquén Dr. Eduardo Castro Rendón. mtassin@hospitalneuquen.org.ar
authors: Mauro
authors: M
authors: Tassin
authors: Pablo
authors: P
authors: Llarena
authors: Federico
authors: F
authors: Laffaye
authors: Germán
authors: G
authors: Kaltenbach
mesh_terms: D004211:Disseminated Intravascular Coagulation / Q000150:complications*; D006801:Humans; D007223:Infant; D008297:Male; D020151:Protein C Deficiency / Q000150:complications*; D018805:Sepsis / Q000150:complications*; D020246:Venous Thrombosis / Q000150:complications*