title: Vitamin D level and basal cell carcinoma, squamous cell carcinoma, and melanoma risk.
abstract: Various associations between serum vitamin D levels and skin cancer have been reported. In this issue, van der Pols et al. observed that baseline 25-hydroxyvitamin D (25OHD) levels above 75 nmol/L were associated with an increased incidence of basal cell carcinoma and melanoma, and a nonstatistically significant decreased incidence of squamous cell carcinoma. Complex factors including sun exposure, skin phototype, and anticarcinogenic and procarcinogenic effects of vitamin D are potential causes of the observed associations.
authors: Kaiser Permanente Medical Group, Honolulu, Hawaii, USA. Electronic address: kavithareddymd@gmail.com.
authors: Kavitha K
authors: KK
authors: Reddy
mesh_terms: D002280:Basal Cell Carcinoma / Q000453:epidemiology*; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000453:epidemiology*; D012878:Skin Neoplasms / Q000453:epidemiology*; D013472:Sunlight / Q000009:adverse effects*; D014807:Vitamin D / Q000097:blood*
chemical_list: D014807:Vitamin D