title: Biochemical markers of bone turnover during pregnancy in horses: a longitudinal study.
abstract: The effect of pregnancy on bone metabolism was investigated in healthy mares. Venous blood samples were collected 7 times from 19 multiparous mares starting at 20-weeks pre-parturition, continuing 6 times in 4-week intervals, including the week of parturition and one week after parturition. Serum concentrations of osteocalcin (OC) and carboxy-terminal cross-linking telopeptide of type I collagen (CTX-I) were determined. Measurement cycles and age had a significant (p < 0.01) influence on OC and CTX-I values. Pregnancy influenced bone metabolism with peak bone formation and resorption values around the time of parturition.
authors: Haflingergestut Meura, Meura, Germany.
authors: C
authors: C
authors: Greiner
authors: E
authors: E
authors: Cavalier
authors: B
authors: B
authors: Remy
authors: A
authors: A
authors: Gabriel
authors: F
authors: F
authors: Farnir
authors: Z
authors: Z
authors: Gajewski
authors: B
authors: B
authors: Carstanjen
mesh_terms: D000818:Animals; D015415:Biomarkers; D015519:Bone Density; D001842:Bone and Bones / Q000378:metabolism*; D024042:Collagen Type I / Q000097:blood / Q000378:metabolism; D005260:Female; D006736:Horses / Q000502:physiology*; D008137:Longitudinal Studies; D015675:Osteocalcin / Q000097:blood / Q000378:metabolism; D010455:Peptides / Q000097:blood / Q000378:metabolism; D058725:Peripartum Period / Q000502:physiology; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000502:physiology
chemical_list: D015415:Biomarkers; D024042:Collagen Type I; D010455:Peptides; C052929:collagen type I trimeric cross-linked peptide; D015675:Osteocalcin