title: Combined effects of sensory cueing and limb activation on unilateral neglect in subacute left hemiplegic stroke patients: a randomized controlled pilot study.
abstract: OBJECTIVE
  To compare the effects of contralesional sensory cueing and limb activation with that of sham control in the treatment of unilateral neglect after stroke.
  
  
  METHODS
  A randomized, single-blinded, sham-controlled pilot study.
  
  
  METHODS
  Two rehabilitation hospitals.
  
  
  METHODS
  Forty subacute left hemiplegic stroke inpatients with unilateral neglect.
  
  
  METHODS
  Participants were assigned randomly to 1 of 2 groups. The experimental group wore a wristwatch cueing device over the hemiplegic arm for three hours a day, five days per week, for three weeks, and also underwent conventional rehabilitation. Patients were encouraged to move their hemiplegic arm five consecutive times after each prompt. The sham group underwent the same rehabilitation process, except they wore a sham device.
  
  
  METHODS
  Neglect, arm motor performance, and overall functioning were assessed pre- and posttraining, and at follow-up.
  
  
  RESULTS
  There were no significant differences between groups in outcome measures except the neglect drawing tasks (p = 0.034) (the mean gain score from baseline to follow-up assessment was 5.2 (3.7) in the experimental group and 1.9 (3.5) in the sham group), across three time intervals. The experimental group showed greater improvement in arm motor performance than did the sham group.
  
  
  CONCLUSIONS
  The results did not confirm that sensory cueing and limb activation treatment is effective when compared with those receiving placebo to reduce unilateral neglect, but it might be useful for promoting hemiplegic arm performance in stroke patients.
authors: Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong. rsnkfong@inet.polyu.edu.hk
authors: Kenneth N K
authors: KN
authors: Fong
authors: Nicole Y H
authors: NY
authors: Yang
authors: Marko K L
authors: MK
authors: Chan
authors: Dora Y L
authors: DY
authors: Chan
authors: Andy F C
authors: AF
authors: Lau
authors: Dick Y W
authors: DY
authors: Chan
authors: Joyce T Y
authors: JT
authors: Cheung
authors: Hobby K Y
authors: HK
authors: Cheung
authors: Raymond C K
authors: RC
authors: Chung
authors: Chetwyn C H
authors: CC
authors: Chan
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D001132:Arm / Q000502:physiology / Q000503:physiopathology*; D003463:Cues; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006429:Hemiplegia / Q000209:etiology / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D010865:Pilot Projects; D012047:Rehabilitation Centers; D012677:Sensation / Q000502:physiology*; D020521:Stroke / Q000150:complications; D000071939:Stroke Rehabilitation
keywords: Sensory cueing; hemiplegic upper extremity; limb activation; subacute stroke; unilateral neglect