title: XtalFluor-E, an efficient coupling reagent for amidation of carboxylic acids.
abstract: Amides were produced from carboxylic acids and amines by using XtalFluor-E as an activator. Even poorly reactive carboxylic acids can be transformed to amides. In addition, optically active amines and/or carboxylic acids were not epimerized/racemized during the process.
authors: Laboratoire de Chimie Organique, ESPCI ParisTech, CNRS, 10 rue Vauquelin, 75231 Paris Cedex 05, France.
authors: Aurélie
authors: A
authors: Orliac
authors: Domingo
authors: D
authors: Gomez Pardo
authors: Agnès
authors: A
authors: Bombrun
authors: Janine
authors: J
authors: Cossy
mesh_terms: D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000737:chemistry*; D002264:Carboxylic Acids / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006845:Hydrocarbons, Fluorinated / Q000737:chemistry*; D007202:Indicators and Reagents; D015394:Molecular Structure; D013457:Sulfur Compounds / Q000737:chemistry*
chemical_list: D000577:Amides; D000588:Amines; D002264:Carboxylic Acids; D006845:Hydrocarbons, Fluorinated; D007202:Indicators and Reagents; D013457:Sulfur Compounds; C551695:diethylaminodifluorosulfinium tetrafluoroborate