title: Prediction factors of postoperative hyperbilirubinemia in living right lobe donor: a single-center analysis of 210 cases.
abstract: BACKGROUND
  Hyperbilirubinemia in living liver donor is very common, but the causes are still unclear.
  
  
  OBJECTIVE
  We sought to clarify the risk factors and predictors of nonobstructive hyperbilirubinemia among living donors.
  
  
  METHODS
  We divided 210 consecutive right liver lobe donors into two groups according to the peak total bilirubin postoperatively. We collected data on preoperative, intraoperative, and postoperative biochemical measurements retrospectively, performing multivariate logistic regression analysis adjusting for potential confounders of the risk of hyperbilirubinemia.
  
  
  RESULTS
  There were significant differences between the two groups in donor age, body mass index, operative time, blood loss, macrovescicular steatosis, allogeneic blood transfusion rate, intensive care unit stay, hospital stay and Clavien score after donation (P < .05). Age, graft/donor weight, operative time, and blood loss were significantly associated with the risk of hyperbilirubinemia upon logistic regression analysis.
  
  
  CONCLUSIONS
  Hyperbilirubinemia, one type of hepatic dysfunction after a living donor procedure, was associated with multiple independent risk factors.
authors: Liver Transplantation Center, West China Hospital of Sichuan University, Chengdu, China.
authors: J Y
authors: JY
authors: Lei
authors: L N
authors: LN
authors: Yan
authors: W T
authors: WT
authors: Wang
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D006498:Hepatectomy / Q000009:adverse effects / Q000379:methods; D006801:Humans; D006932:Hyperbilirubinemia / Q000150:complications* / Q000175:diagnosis*; D008099:Liver / Q000473:pathology / Q000601:surgery; D017093:Liver Failure / Q000601:surgery*; D008111:Liver Function Tests; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011184:Postoperative Period; D011237:Predictive Value of Tests; D012044:Regression Analysis; D012307:Risk Factors