title: Patterns of renal angiomyolipoma regression post embolisation on medium- to long-term follow-up.
abstract: OBJECTIVE
  To assess the patterns of regression of renal angiomyolipoma (AML) post embolisation and report the outcomes related to the use of different embolic materials.
  
  
  METHODS
  A retrospective review of all patients who underwent embolisation for renal AML at our institution between January 2004 and April 2012.
  
  
  RESULTS
  13 patients underwent 16 episodes of embolisation. Coils were used as the primary embolisation material in 10 episodes and microspheres in 6 episodes. The size reduction rate highly correlated on CT follow-up between the two groups, with 25.6% vs 22.7% reduction at 12 months, 27.5% vs 25.1% at 24 months, 35.0% vs 33.0% at 36 months and 35.0% vs 36.8% at 48 months. During follow-up, all tumours reduced in size with one patient requiring subsequent embolisation whose tumour reduced by only 6.5% after 1 year and subsequently exhibited regrowth after 4 years. Two patients presented with rebleeding and underwent repeat embolisation. Our overall retreatment rate (23%) is well within the literature range (up to 37%). None of the patients underwent surgery.
  
  
  CONCLUSIONS
  The majority of AML shrinkage occurs within the first year following embolisation and appears to plateau after 3 years, which could have an impact on follow-up strategy. The percentage reduction at 1 year may reflect the long-term effect of embolisation with tumours demonstrating minor size reduction more likely to relapse at long-term follow-up. Embolisation of renal AML produces durable long-term results regardless of the choice of embolic agent.
  
  
  CONCLUSIONS
  These findings provide information to guide CT follow-up of renal AML post embolisation.
authors: Vascular Radiology Department, Hull Royal Infirmary, Hull, UK. kpatatas@hotmail.com
authors: K
authors: K
authors: Patatas
authors: G J
authors: GJ
authors: Robinson
authors: D F
authors: DF
authors: Ettles
authors: R
authors: R
authors: Lakshminarayan
mesh_terms: D018207:Angiomyolipoma / Q000000981:diagnostic imaging* / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome
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