title: Hemoperitoneum secondary to gastric GIST negative for c-KIT and positive for antibody anti-DOG1.
abstract: Although relatively rare, the gastrointestinal stromal tumors comprise most mesenchymal tumors of the digestive tract and account for 5% of all sarcomas. The most common symptoms are pain, gastrointestinal bleeding and palpable mass. This study reported the case of a young patient who developed hemoperitoneum due to gastric neoplasm rupture and required urgent surgical treatment. Pathology and immunohistochemistry analysis showed an epidemiologically rare case: epithelioid and c-KIT negative tumor.
authors: Serviço de Cirurgia Geral, Universidade de Santo Amaro, São Paulo, SP.
authors: Marina Gabrielle
authors: MG
authors: Epstein
authors: Aline Fioravanti
authors: AF
authors: Pasquetti
authors: Sara Venoso
authors: SV
authors: Costa
authors: Murillo de Lima
authors: Mde L
authors: Favaro
authors: Orlando
authors: O
authors: Contrucci Filho
authors: Marcelo Augusto Fontenelle
authors: MA
authors: Ribeiro Junior
mesh_terms: D000328:Adult; D000075369:Anoctamin-1; D014408:Biomarkers, Tumor / Q000032:analysis; D018118:Chloride Channels / Q000032:analysis*; D046152:Gastrointestinal Stromal Tumors / Q000150:complications*; D006465:Hemoperitoneum / Q000209:etiology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009363:Neoplasm Proteins / Q000032:analysis*; D019009:Proto-Oncogene Proteins c-kit / Q000032:analysis*; D013274:Stomach Neoplasms / Q000150:complications*
chemical_list: C476213:ANO1 protein, human; D000075369:Anoctamin-1; D014408:Biomarkers, Tumor; D018118:Chloride Channels; D009363:Neoplasm Proteins; D019009:Proto-Oncogene Proteins c-kit