title: Personalised intervention for people with depression and severe COPD.
abstract: Chronic obstructive pulmonary disease (COPD) is often complicated by depression and exemplifies the challenge in managing chronic illnesses that require active patient participation in care. In a clinical trial (NCT00151372), we compared a novel personalised intervention for depression and COPD (PID-C) targeting treatment adherence with treatment as usual (TAU). In 138 patients with major depression and severe COPD, PID-C led to a higher remission rate and a greater reduction in depressive symptoms and in dyspnoea-related disability than TAU over 28 weeks and 6 months after the last session. If replicated, PID-C may serve as a care model for patients with both depression and medical illnesses with a deteriorating course.
authors: Weill Cornell Medical Center, 21 Bloomingdale Road, White Plains, NY 10605, USA. gsalexop@med.cornell.edu
authors: George S
authors: GS
authors: Alexopoulos
authors: Dimitris N
authors: DN
authors: Kiosses
authors: Jo Anne
authors: JA
authors: Sirey
authors: Dora
authors: D
authors: Kanellopoulos
authors: Richard S
authors: RS
authors: Novitch
authors: Samiran
authors: S
authors: Ghosh
authors: Joanna K
authors: JK
authors: Seirup
authors: Patrick J
authors: PJ
authors: Raue
mesh_terms: D000328:Adult; D003865:Major Depressive Disorder / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D018450:Disease Progression; D004417:Dyspnea / Q000517:prevention & control; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D057194:Intention to Treat Analysis; D009010:Monte Carlo Method; D017063:Outcome Assessment, Health Care / Q000706:statistics & numerical data*; D010349:Patient Compliance / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000503:physiopathology / Q000534:rehabilitation*; D012074:Remission Induction; D016019:Survival Analysis
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