title: Performance asymmetries in tool use are associated with corpus callosum integrity in chimpanzees (Pan troglodytes): a diffusion tensor imaging study.
abstract: The authors examined the relationship of corpus callosum (CC) morphology and organization to hand preference and performance on a motor skill task in chimpanzees. Handedness was assessed using a complex tool use task that simulated termite fishing. Chimpanzees were initially allowed to perform the task wherein they could choose which hand to use (preference measure), then they were required to complete trials using each hand (performance measure). Two measures were used to assess the CC: midsagittal area obtained from in vivo magnetic resonance images and density of transcallosal connections as determined by fractional anisotropy values obtained from diffusion tensor imaging. The authors hypothesized that chimpanzees would perform better on their preferred hand compared to the nonpreferred hand, and that strength of behavioral lateralization (rather the direction) on this task would be negatively correlated to regions of the CC involved in motor processing. Results indicate that the preferred hand was the most adept hand. Performance asymmetries correlated with fractional anisotropy measures but not area measures of the CC.
authors: Department of Psychology, Trinity University, 1 Trinity Place, San Antonio, TX 78212, USA. Kimberley.Phillips@Trinity.edu
authors: Kimberley A
authors: KA
authors: Phillips
authors: Jennifer
authors: J
authors: Schaeffer
authors: Elizabeth
authors: E
authors: Barrett
authors: William D
authors: WD
authors: Hopkins
mesh_terms: D000818:Animals; D016880:Anisotropy; D001931:Brain Mapping; D003337:Corpus Callosum / Q000033:anatomy & histology* / Q000502:physiology; D056324:Diffusion Tensor Imaging; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D007091:Image Processing, Computer-Assisted; D008297:Male; D002679:Pan troglodytes / Q000033:anatomy & histology* / Q000502:physiology; D053001:Tool Use Behavior / Q000502:physiology*
references: Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12634-8
references: 16105943
references: J Neurosci. 2007 Sep 19;27(38):10106-15
references: 17881517
references: Behav Neurosci. 2006 Oct;120(5):1025-32
references: 17014254
references: Cereb Cortex. 2007 Aug;17(8):1757-65
references: 17012376
references: Neuroimage. 2006 Sep;32(3):989-94
references: 16854598
references: Cereb Cortex. 2013 Feb;23(2):411-22
references: 22368087
references: Behaviour. 2009 Jan 1;146(11):1463-1483
references: 20221316
references: J Comp Psychol. 2000 Jun;114(2):126-35
references: 10890584
references: Comput Methods Programs Biomed. 2006 Feb;81(2):106-16
references: 16413083
references: J Comp Psychol. 2001 Dec;115(4):418-422
references: 11824905
references: Arch Neurol. 1995 May;52(5):501-8
references: 7733846
references: Neurosci Biobehav Rev. 1996 Winter;20(4):587-91
references: 8994197
references: Magn Reson Med. 1998 Jun;39(6):928-34
references: 9621916
references: Eur J Neurol. 2001 Sep;8(5):425-34
references: 11554905
references: Brain. 1989 Jun;112 ( Pt 3):799-835
references: 2731030
references: Am J Phys Anthropol. 2004 Sep;125(1):30-41
references: 15293329
references: Laterality. 2007 Jul;12(4):364-77
references: 17558818
references: Brain Lang. 2002 Dec;83(3):403-24
references: 12468396
references: Biophys J. 1994 Jan;66(1):259-67
references: 8130344
references: Neuropsychologia. 2004;42(7):990-6
references: 14998713
references: J Magn Reson B. 1996 Jun;111(3):209-19
references: 8661285
references: Brain Res. 1991 Apr 5;545(1-2):175-82
references: 1860044
references: J Neurosci. 2008 Dec 24;28(52):14132-9
references: 19109495
references: Brain. 1998 Dec;121 ( Pt 12):2369-79
references: 9874487
references: Am J Primatol. 2008 Mar;70(3):254-60
references: 17894405
references: Exp Brain Res. 1994;102(2):227-43
references: 7705502
references: PLoS One. 2012;7(2):e31941
references: 22355406
references: J Comp Neurol. 1986 May 15;247(3):297-325
references: 3722441
references: Neuropsychologia. 1971 Mar;9(1):97-113
references: 5146491
references: Percept Mot Skills. 1992 Dec;75(3 Pt 1):851-66
references: 1454487
references: Psychol Bull. 1991 Jan;109(1):76-89
references: 2006230
references: Neuroimage. 2010 Aug 1;52(1):43-9
references: 20394828
references: Brain Cogn. 1993 Jul;22(2):171-81
references: 8373571
references: J Comp Psychol. 1992 Dec;106(4):392-7
references: 1451422
references: Brain Cogn. 1991 May;16(1):41-61
references: 1854469
references: NMR Biomed. 1995 Nov-Dec;8(7-8):333-44
references: 8739270