title: Efficient quenching of electrochemiluminescence from K-doped graphene-CdS:Eu NCs by G-quadruplex-hemin and target recycling-assisted amplification for ultrasensitive DNA biosensing.
abstract: Based on the K-doped graphene-CdS:Eu NC composites and the nicking endonuclease (NEase) assisted strand-scission cycle, we have developed an ultrasensitive and selective electrochemiluminescence (ECL) DNA biosensor using the G-quadruplex-hemin-based DNAzyme which acts as an electrocatalyst for the reduction of H(2)O(2), the coreactant of CdS:Eu NCs ECL.
authors: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China.
authors: Hong
authors: H
authors: Zhou
authors: Yan-Yan
authors: YY
authors: Zhang
authors: Jing
authors: J
authors: Liu
authors: Jing-Juan
authors: JJ
authors: Xu
authors: Hong-Yuan
authors: HY
authors: Chen
mesh_terms: D055162:Biocatalysis; D015374:Biosensing Techniques; D019187:Cadmium Compounds / Q000737:chemistry; D004247:DNA / Q000032:analysis*; D021881:DNA, Catalytic / Q000737:chemistry / Q000378:metabolism; D055664:Electrochemical Techniques; D004720:Endonucleases / Q000737:chemistry / Q000378:metabolism; D005063:Europium / Q000737:chemistry; D054856:G-Quadruplexes; D006108:Graphite / Q000737:chemistry; D006427:Hemin / Q000737:chemistry*; D006861:Hydrogen Peroxide / Q000737:chemistry / Q000378:metabolism; D049449:Luminescence; D008163:Luminescent Measurements; D049329:Nanostructures / Q000737:chemistry*; D010084:Oxidation-Reduction; D010316:Particle Size; D012666:Semiconductors; D013440:Sulfides / Q000737:chemistry; D013499:Surface Properties
chemical_list: D019187:Cadmium Compounds; D021881:DNA, Catalytic; D013440:Sulfides; C034939:cadmium sulfide; D005063:Europium; D006427:Hemin; D006108:Graphite; D004247:DNA; D006861:Hydrogen Peroxide; D004720:Endonucleases