title: Single molecular functionalized gold nanoparticles for hydrogen-bonding recognition and colorimetric detection of dopamine with high sensitivity and selectivity.
abstract: In this work, we developed a low-cost, facile, sensitive, and selective colorimetric method for the quantitative determination of dopamine, based on 4-amino-3-hydrazino-5-mercapto-1,2,4-triazol (AHMT) functionalized gold nanoparticles (AHMP-AuNPs) as a model probe. Dopamine could induce the aggregation of the AHMT-AuNPs through hydrogen-bonding interactions, which caused the colloidal solution changed from red to blue. And the color change was in situ monitored for the quantitative determination of dopamine in human serum and urine samples. The developed approach is simple, without using complex financial instruments and adding other metal salts or ions for improving sensitivity.
authors: College of Geography and Environmental Science, College of Chemistry and Life Science, Zhejiang Normal University, Jinhua 321004, China.
authors: Jiu-Ju
authors: JJ
authors: Feng
authors: Han
authors: H
authors: Guo
authors: Yong-Fang
authors: YF
authors: Li
authors: Yun-Hua
authors: YH
authors: Wang
authors: Wan-Yi
authors: WY
authors: Chen
authors: Ai-Jun
authors: AJ
authors: Wang
mesh_terms: D003124:Colorimetry / Q000379:methods*; D004298:Dopamine / Q000032:analysis* / Q000097:blood / Q000652:urine; D006046:Gold / Q000737:chemistry*; D006801:Humans; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D053768:Metal Nanoparticles; D046529:Microscopy, Electron, Transmission
chemical_list: D006046:Gold; D004298:Dopamine