title: Recruitment of black subjects for a natural history study of intracerebral hemorrhage.
abstract: Historically, recruitment of minority subjects for clinical research has been challenging. We developed culturally-tailored recruitment materials for a longitudinal, natural history study of intracerebral hemorrhage (ICH) and trained recruiting coordinators in cultural competence. Of 285 subjects meeting inclusion criteria, 158 (55% of those eligible) agreed to participate (60% of eligible Blacks vs. 45% of eligible non-Blacks, p..02). Of those enrolled, 138 (87%) agreed to participate in the genetic sub-study (86% of Blacks vs. 90% of non-Blacks enrolled, p..78). Of those subjects who refused enrollment, lack of interest in research (42%) was the most common reason given for the study as a whole. A higher rate of enrollment was achieved in Blacks vs. non-Blacks in this ICH clinical research study employing culturally tailored recruitment approaches and training of recruitment coordinators to overcome traditional recruitment barriers to research participation in minority patients.
authors: Departments of Kinesiology and Neurology, University of Wisconsin, Madison, WI, USA. dfedwards@wisc.edu
authors: Dorothy F
authors: DF
authors: Edwards
authors: Ravi
authors: R
authors: Menon
authors: Ali
authors: A
authors: Fokar
authors: Christopher
authors: C
authors: Gibbons
authors: Jeffrey
authors: J
authors: Wing
authors: Brisa
authors: B
authors: Sanchez
authors: Chelsea S
authors: CS
authors: Kidwell
mesh_terms: D001741:Black or African American; D001057:Apolipoproteins E / Q000097:blood / Q000502:physiology; D002543:Cerebral Hemorrhage / Q000235:genetics / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D045808:Refusal to Participate
chemical_list: D001057:Apolipoproteins E
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