title: Single continuous wave laser induced photodynamic/plasmonic photothermal therapy using photosensitizer-functionalized gold nanostars.
abstract: Chlorin e6 conjugated gold nanostars (GNS-PEG-Ce6) are used to perform simultaneous photodynamic/plasmonic photothermal therapy (PDT/PPTT) upon single laser irradiation. The early-phase PDT effect is coordinated with the late-phase PPTT effect to obtain synergistic anticancer efficiency. The prepared GNS-PEG-Ce6 shows excellent water dispersibility, good biocompatibility, enhanced cellular uptake and remarkable anticancer efficiency upon irradiation in vivo.
authors: Department of Medical Imaging, Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing, Jiangsu 210000, China.
authors: Shouju
authors: S
authors: Wang
authors: Peng
authors: P
authors: Huang
authors: Liming
authors: L
authors: Nie
authors: Ruijun
authors: R
authors: Xing
authors: Dingbin
authors: D
authors: Liu
authors: Zhe
authors: Z
authors: Wang
authors: Jing
authors: J
authors: Lin
authors: Shouhui
authors: S
authors: Chen
authors: Gang
authors: G
authors: Niu
authors: Guangming
authors: G
authors: Lu
authors: Xiaoyuan
authors: X
authors: Chen
mesh_terms: D000818:Animals; D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy; D045744:Cell Line, Tumor; D002471:Cell Transformation, Neoplastic; D006046:Gold / Q000737:chemistry*; D006801:Humans; D007834:Lasers; D053768:Metal Nanoparticles / Q000737:chemistry*; D051379:Mice; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000737:chemistry* / Q000627:therapeutic use
chemical_list: D017319:Photosensitizing Agents; D006046:Gold
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