title: Contemporary views on the ossification of the ligamenta flava.
abstract: The ligamenta flava, together with the vertebral lamina, form the posterior wall of the spinal canal. Since they are located immediately adjacent to the nerve structures of the spinal cord, every pathology that involves hypertrophy produces neurological disturbances as a result. One of the most common reasons for hypertrophy of the ligamenta flava is heterotopic ossification. The main regions of the world where this disorder occurs are the Asian countries, especially Japan, but there are increasing numbers of such cases in other populations. The most important causes of the formation of ectopic osseous tissue in the vicinity of the ligamenta flava are thought to be mechanical stress and genetic predisposition. Treatment is mostly limited to surgical procedures. The present study is a review of the current state of our knowledge concerning the ossification of the ligamenta flava, the sequelae of this pathology, and the treatment methods.
authors: Department of Anatomy, Collegium Medicum, Jagiellonian University, Poland. mcklosinski@poczta.onet.pl
authors: Michał
authors: M
authors: Kłosiński
authors: Janusz
authors: J
authors: Skrzat
authors: Jerzy
authors: J
authors: Walocha
authors: Ewa
authors: E
authors: Mizia
mesh_terms: D044466:Asian People / Q000706:statistics & numerical data*; D015897:Comorbidity; D020022:Genetic Predisposition to Disease; D006304:Health Status; D006801:Humans; D017843:Ligamentum Flavum / Q000473:pathology*; D009999:Ossification, Heterotopic / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology / Q000628:therapy; D015995:Prevalence; D012307:Risk Factors; D013118:Spinal Cord Diseases / Q000175:diagnosis / Q000208:ethnology* / Q000235:genetics / Q000628:therapy