title: Recurrent sinonasal melanoma--report of five surgical cases and short literature review.
abstract: The aim of this study is to present five surgical cases of recurrent sinonasal melanoma. We report the clinical course of this highly malignant disease and give a brief overview of the relevant literature. For the purpose of our presentation, inclusion criteria for all patients were initally negative surgical margins, surgery with curative intent without implementation of radiotherapy, and absence of distant metastatic spread at presentation (MO). They were diagnosed and treated at the same ENT/Head and Neck Surgery department and had clear surgical margins following first resection. The majority of five cases had local recurrences (average two) which were all amenable to at least one salvage operation. In conclusion, despite extensive disease at presentation, we recommend repeated attempts at local surgical salvage. However, this decision must be carefully considered, respecting postoperative quality of life, the estimated life expectancy as well as general socioeconomic issues in each particular case.
authors: University of Zagreb, Sestre milosrdnice University Hospital Center, Department of ENT - Head and Neck Surgery, Zagreb, Croatia. dzepina.davor@gmail.com
authors: Davor
authors: D
authors: Dzepina
authors: Livije
authors: L
authors: Kalogjera
authors: Tomislav
authors: T
authors: Baudoin
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009669:Nose Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D010256:Paranasal Sinuses / Q000000981:diagnostic imaging / Q000473:pathology*; D012008:Recurrence; D014057:Tomography, X-Ray Computed