title: In vitro maturation of oocytes: uncommon indications.
abstract: Retrieval of immature oocytes from unstimulated ovaries, followed by in vitro maturation (IVM) was initially proposed to avoid the risks and side effects of exogenous gonadotropin administration. Therefore, during the past decades, IVM was mainly offered to patients with polycystic ovary syndrome (PCOS) at high risk of ovarian hyperstimulation syndrome (OHSS). However, the development of fertility preservation has recently opened new perspectives in the field of IVM. The present review summarizes uncommon indications of IVM, which is a viable option to treat infertility in patients with ovarian resistance to FSH, but may also be considered to preserve fertility in leukemia as well as before ovarian transposition and endometrioma excision.
authors: Service de Gynécologie-Obstétrique et Médecine de la Reproduction, Hôpital Antoine Béclère, Clamart, Universite Paris-Sud, Clamart, France. michael.grynberg@abc.aphp.fr
authors: Michael
authors: M
authors: Grynberg
authors: Hady
authors: H
authors: El Hachem
authors: Astrid
authors: A
authors: de Bantel
authors: Julie
authors: J
authors: Benard
authors: Soizic
authors: S
authors: le Parco
authors: Renato
authors: R
authors: Fanchin
mesh_terms: D005260:Female; D005298:Fertility / Q000502:physiology*; D059247:Fertility Preservation / Q000379:methods*; D006801:Humans; D059471:In Vitro Oocyte Maturation Techniques / Q000379:methods*; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D007938:Leukemia / Q000628:therapy; D054315:Oocyte Retrieval; D009865:Oocytes / Q000166:cytology*; D011085:Polycystic Ovary Syndrome / Q000150:complications*; D011247:Pregnancy