title: PPA-mediated C-C bond formation: a synthetic route to substituted indeno[2,1-c]quinolin-6(7H)-ones.
abstract: A facile and efficient synthesis of substituted indeno[2,1-c]quinolin-6(7H)-ones from a variety of α-acyl N-arylcinnamamides mediated by polyphosphoric acid (PPA) is described, and a mechanism involving the formation of a dicationic superelectrophile and subsequent double intramolecular nucleophilic cyclization reactions is proposed.
authors: Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
authors: Xu
authors: X
authors: Liu
authors: Qian
authors: Q
authors: Zhang
authors: Dingyuan
authors: D
authors: Zhang
authors: Xiaoqing
authors: X
authors: Xin
authors: Rui
authors: R
authors: Zhang
authors: Fenguo
authors: F
authors: Zhou
authors: Dewen
authors: D
authors: Dong
mesh_terms: D002384:Catalysis; D003500:Cyclization; D006576:Heterocyclic Compounds, 4 or More Rings / Q000138:chemical synthesis* / Q000737:chemistry; D007192:Indenes / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010756:Phosphoric Acids / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D015363:Quinolones / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D006576:Heterocyclic Compounds, 4 or More Rings; D007192:Indenes; D010756:Phosphoric Acids; D011108:Polymers; D015363:Quinolones; C047269:polyphosphoric acid