title: [Prevalence of Acinetobacter baumannii and Pseudomonas aeruginosa isolates resistant to imipenem by production of metallo-β-lactamases in Rabat Military Teaching Hospital Mohammed V].
abstract: We studied the production of metallo-β-lactamases (MBL) in Acinetobacter baumannii and Pseudomonas aeruginosa strains resistant to imipenem at the Rabat Mohammed V military teaching hospital, according to Yong et al.'s method, using a sterilized solution of EDTA 0.5 M pH 8. One hundred and five bacterial strains (48 A. baumannii and 57 P. aeruginosa) were identified. 45 (42.9%) with 34 A. baumannii and 11 P. aeruginosa were resistant to imipenem. The prevalence of MBL producing strains was 22.2% (10/45). The existence of this isolates resistant to imipenem by producing metallo-β-lactamases is an emerging public health problem. It is necessary to implemente infection control programs to avoid spreading of multidrug resistant bacteria.
authors: Laboratoire de bactériologie, Hôpital militaire d'instruction Mohammed V, Rabat, Maroc. comlanz@yahoo.fr
authors: Alban
authors: A
authors: Gildas Comlan Zohoun
authors: Danièle
authors: D
authors: Moket
authors: Sakina
authors: S
authors: El Hamzaoui
mesh_terms: D000151:Acinetobacter Infections / Q000453:epidemiology* / Q000382:microbiology; D040981:Acinetobacter baumannii / Q000201:enzymology / Q000302:isolation & purification / Q000378:metabolism; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D024881:Drug Resistance, Bacterial; D005260:Female; D006772:Hospitals, Military / Q000706:statistics & numerical data; D006784:Hospitals, Teaching / Q000706:statistics & numerical data; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use*; D008297:Male; D009018:Morocco / Q000453:epidemiology; D015995:Prevalence; D011552:Pseudomonas Infections / Q000453:epidemiology* / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000201:enzymology / Q000302:isolation & purification / Q000378:metabolism; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D015378:Imipenem; D001618:beta-Lactamases
keywords: Acinetobacter baumannii; Pseudomonas aeruginosa; imipenem; metallo-β-lactamase; resistance