title: Synthesis, crystal structure and antibacterial activity of new highly functionalized ionic compounds based on the imidazole nucleus.
abstract: Several new highly functionalized imidazolium derivatives were synthesized, via appropriate synthetic routes, using imidazole, 1-methylimidazole and 2-phenyl-1-methylimidazole as key intermediates. The antibacterial activity of the prepared compounds was evaluated against: Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Salmonella thipymurium using disk-diffusion and MIC methods. Crystal X-ray structures are reported for six compounds.
authors: Laboratoire des Produits Naturels d'Origine Végétale et de Synthèse Organique, Université Mentouri-Constantine, Constantine 25000, Algeria.
authors: Mebarek
authors: M
authors: Bahnous
authors: Abdelmalek
authors: A
authors: Bouraiou
authors: Meryem
authors: M
authors: Chelghoum
authors: Sofiane
authors: S
authors: Bouacida
authors: Thierry
authors: T
authors: Roisnel
authors: Farida
authors: F
authors: Smati
authors: Chafia
authors: C
authors: Bentchouala
authors: Philippe C
authors: PC
authors: Gros
authors: Ali
authors: A
authors: Belfaitah
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D018360:Crystallography, X-Ray; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D008958:Models, Molecular; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D007093:Imidazoles