title: Measurement of subclinical carotid atherosclerosis may help in predicting risk for stroke in patients with diabetes.
abstract: Diabetes is one of the most important risk factor for stroke and cardiovascular disease (CVD), especially in young patients. The control of classical vascular risk factors failed in terms of prevention of stroke in patients with diabetes. In addiction, in these patients the glycemic control showed a benefit on microvascular disease but lacked an established benefit in macrovascular disease. Therefore, implementations of effective stroke prevention strategies appear necessary in patients with diabetes. Ultrasound surrogate or intermediate markers of carotid atherosclerosis include carotid intima-media thickness (cIMT), carotid plaque (CP), and carotid stiffness (STIFF) have been demonstrated to increase in patients with diabetes and to be able to predict risk for stroke. In this editorial we discuss the opportunity to prevent the onset of vascular disease in their "preclinical or subclinical" stage in patients with higher risk for stroke such as diabetic patients.
authors: Department of Neurology, Miller School of Medicine, University of Miami, Clinical Research Building, Miami, FL 33136, USA. ddellamorte@med.miami.edu
authors: David
authors: D
authors: Della-Morte
authors: Camillo
authors: C
authors: Ricordi
authors: Fiorella
authors: F
authors: Guadagni
authors: Tatjana
authors: T
authors: Rundek
mesh_terms: D015415:Biomarkers; D002340:Carotid Artery Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D059168:Carotid Intima-Media Thickness; D048909:Diabetes Complications / Q000000981:diagnostic imaging / Q000209:etiology*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D011237:Predictive Value of Tests; D018570:Risk Assessment; D020521:Stroke / Q000209:etiology*
chemical_list: D015415:Biomarkers
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