title: Granuloma annulare-like reaction to the bacillus Calmette-Guerin vaccination.
abstract: We report the case of a 6-month-old girl with a granuloma annulare (GA)-like reaction to the bacillus Calmette-Guerin (BCG) vaccination. The eruption developed at the vaccination site 1 month after vaccination and the lesion gradually disseminated over the body within 2 months. A biopsy specimen of the skin lesion showed degenerated collagen bundles surrounded by imperfect palisading histiocytes, lymphocytes and epithelioid cells in the dermis, which led to a diagnosis of GA-like reaction as a secondary reaction to BCG inoculation. The eruption at the vaccination site and the scattered GA reaction resolved after 1 month of treatment with prednisolone valerate acetate ointment, leaving only pigmentation.
authors: Department of Dermatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, JR Osaka Hospital, Osaka, Japan. tomoko-k@koto.kpu-m.ac.jp
authors: Tomoko
authors: T
authors: Nomiyama
authors: Hideya
authors: H
authors: Takenaka
authors: Saburo
authors: S
authors: Kishimoto
authors: Norito
authors: N
authors: Katoh
mesh_terms: D000276:Adjuvants, Immunologic / Q000009:adverse effects*; D001500:BCG Vaccine / Q000009:adverse effects*; D005260:Female; D016460:Granuloma Annulare / Q000139:chemically induced* / Q000175:diagnosis*; D006801:Humans; D007223:Infant
chemical_list: D000276:Adjuvants, Immunologic; D001500:BCG Vaccine