title: Visceral leishmaniasis revealed by a squamous cell carcinoma in an HIV-1 infected patient.
abstract: We present a case of visceral leishmaniasis confirmed after the histological investigation of an ulcerate lesion of the scalp in an HIV-1-infected patient receiving highly active antiretroviral therapy (HAART). Histological examination of the skin lesion revealed a squamous cell carcinoma superinfected by amastigotes of Leishmania infantum from the bloodstream. Because HIV-1-infected individuals can harbour parasitic infections in normal and neoplastic tissue, it is necessary to examine carefully any skin lesions, particularly those with uncommon aspects or a worsening course, to exclude superinfections by unsuspected pathogens.
authors: Dermatopathology Unit, San Gallicano Dermatological Institute (IRCCS), Via Elio Chianesi, 53, 00144, Rome, Italy.
authors: P
authors: P
authors: Donati
authors: G
authors: G
authors: Paolino
authors: C
authors: C
authors: Panetta
authors: L
authors: L
authors: Muscardin
authors: C
authors: C
authors: Cota
authors: M
authors: M
authors: Giuliani
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology*; D000666:Amphotericin B / Q000627:therapeutic use; D019380:Anti-HIV Agents / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D002294:Carcinoma, Squamous Cell / Q000469:parasitology / Q000473:pathology*; D006801:Humans; D015603:Keratinocytes / Q000469:parasitology; D018314:Leishmania infantum / Q000302:isolation & purification*; D007898:Leishmaniasis, Visceral / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged
chemical_list: D019380:Anti-HIV Agents; D000666:Amphotericin B
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