title: The importance of additive and non-additive mutational effects in protein engineering.
authors: Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470 Mülheim an der Ruhr, Germany. reetz@mpi-muelheim.mpg.de
authors: Manfred T
authors: MT
authors: Reetz
mesh_terms: D006860:Hydrogen Bonding; D008958:Models, Molecular; D015394:Molecular Structure; D009154:Mutation; D015202:Protein Engineering / Q000639:trends*; D013816:Thermodynamics