title: Trigeminal somatosensory evoked potentials in trichloroethylene-exposed workers.
abstract: OBJECTIVE
  To assess the value of trigeminal somatosensory evoked potentials (TSEP) in evaluating toxicity of trichloroethylene to the trigeminal nerve.
  
  
  METHODS
  Trichloroethylene (TCE), an excellent fat solvent largely used in industry, has a neurotoxic effect particularly on the trigeminal nerve. In March 2002, several TCE-exposed workers presented to Habib Bourguiba University Hospital, Sfax, Tunisia, for burned or numbness of the face. Twenty-three workers manipulating TCE underwent clinical, biological and toxicological assessment. Neurophysiologic study consisted of the measurement of the latencies and the amplitudes of TSEP in 23 exposed workers and 23 controls.
  
  
  RESULTS
  Abnormal TSEP were observed in 6 workers with clinical evidence of trigeminal involvement and in 9 asymptomatic workers. We observed a significant positive correlation between duration of exposure and the N2 latency (r=0.5, p<0.01) and P2 latency (r=0.6, p<0.02). The sensitivity of TSEP was 65% and the specificity was 100%.
  
  
  CONCLUSIONS
  Trigeminal somatosensory evoked potentials are a useful tool in the diagnosis and management of chronic neurological complications of TCE intoxication. Since alterations of TSEP precede clinical symptoms, trigeminal nerve involvement can be demonstrated at the infra-clinical stage.
authors: Department of Neurology, Habib Bourguiba University Hospital, CP 3.029-Sfax, Tunisia.  Tel. +216 (74) 450581. Fax. +216 (74) 243427. E-mail: chokri.mhiri@rns.tn.
authors: Chokri
authors: C
authors: Mhiri
authors: Fakher
authors: F
authors: Choyakh
authors: Mohamed
authors: M
authors: Ben Hmida
authors: Imed
authors: I
authors: Feki
authors: Mounir
authors: M
authors: Ben Messaud
authors: Nouri
authors: N
authors: Zouari