title: Synthesis of primary and secondary alkylboronates through site-selective C(sp3)-H activation with silica-supported monophosphine-Ir catalysts.
abstract: The site-selective activation and borylation of unactivated C(sp(3))-H bonds in 2-alkylpyridines to form primary and secondary alkylboronates was achieved using silica-supported monophosphine-Ir catalysts. This borylation occurs selectively at C-H bonds located γ to the pyridine nitrogen atom. The site-selectivity of this reaction suggests that the C-H bond cleavage occurs with the assistance of a proximity effect due to N-to-Ir coordination.
authors: Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo 060-0810, Japan.
authors: Soichiro
authors: S
authors: Kawamorita
authors: Ryo
authors: R
authors: Murakami
authors: Tomohiro
authors: T
authors: Iwai
authors: Masaya
authors: M
authors: Sawamura