title: Primary hyperparathyroidism-related brown tumors mimicking other giant cell-containing skeletal tumors: role of correlative imaging in diagnosis.
abstract: A patient initially suspected of having a giant cell granuloma was subsequently found-through additional imaging with (99m)Tc-sestamibi and ultrasound-to have osteolytic brown tumors caused by a parathyroid adenoma. Brown tumors that relate to primary hyperparathyroidism may mimic other skeletal tumors that contain giant cells, presenting difficulty with accurate diagnosis. Correlative imaging can have a valuable role in such cases, potentially avoiding the extensive work-up usually done for suspected bone metastases.
authors: Division of Nuclear Medicine, Department of Radiology, University of Alabama at Birmingham, AL 35249, USA.
authors: Fathima Fijula
authors: FF
authors: Palot Manzil
authors: Pradeep
authors: P
authors: Bhambhvani
authors: Surjith
authors: S
authors: Vattoth
authors: Shree Krishna
authors: SK
authors: Subedi
authors: Asim Kumar
authors: AK
authors: Bag
authors: Janis P
authors: JP
authors: O'Malley
mesh_terms: D001859:Bone Neoplasms / Q000175:diagnosis*; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D005260:Female; D006101:Granuloma, Giant Cell / Q000175:diagnosis*; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000150:complications*; D010010:Osteoclasts / Q000473:pathology*; D010282:Parathyroid Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D055815:Young Adult