title: Sleepiness in patients with obstructive sleep apnoea - daytime course and impact of nocturnal respiratory events.
abstract: BACKGROUND
  Obstructive sleep apnoea (OSA) is a condition leading to excessive daytime sleepiness. The aim of the study was a) to study course of daytime sleepiness in patients with OSA and b) to find the most important nocturnal polysomnography parameters influencing daytime sleepiness in OSA.
  
  
  METHODS
  The cohort consisted of forty-five patients (6 women, 39 men) diagnosed with OSA. All patients underwent polysomnography, Multiple Sleep Latency Test (MSLT) and rated subjectively their daytime tendency to sleep with the Epworth Sleepiness Scale.
  
  
  RESULTS
  Sleep latency was significantly longer at 15:00 and at 17:00 hours compared to previous tests. A significant negative correlation was found between the mean of the MSLT sleep latency and a number of awakenings, the apnoea/hypopnoea index and oxygen desaturation index values.
  
  
  CONCLUSIONS
  The study showed the sleep latency prolongation at 15:00 and 17:00 hours respectively and confirmed connection of excessive daytime sleepiness to fragmentation of nocturnal sleep and OSA severity.
authors: Department of Neurology, Charles University, Prague, Czech Republic.
authors: Simona
authors: S
authors: Dostalova
authors: Marek
authors: M
authors: Susta
authors: Tereza
authors: T
authors: Vorlova
authors: Karel
authors: K
authors: Sonka
mesh_terms: D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000453:epidemiology; D002940:Circadian Rhythm / Q000502:physiology; D015331:Cohort Studies; D015897:Comorbidity; D006970:Disorders of Excessive Somnolence / Q000453:epidemiology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D020187:REM Sleep Behavior Disorder / Q000453:epidemiology / Q000503:physiopathology; D012148:Restless Legs Syndrome / Q000453:epidemiology / Q000503:physiopathology; D012890:Sleep / Q000502:physiology; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology*; D012894:Sleep Stages / Q000502:physiology*; D055815:Young Adult