title: Design and synthesis of stable α-diazo-β-oxo sulfoxides.
abstract: Diazo transfer adjacent to a sulfoxide moiety to provide stable, isolable α-diazo-β-oxo sulfoxides has been achieved. Use of monocyclic and bicyclic sulfoxide precursors is critical in enabling isolation of stable derivatives, through introduction of conformational constraint, while acyclic α-diazo-β-oxo sulfoxides are too labile to isolate and characterize.
authors: Department of Chemistry, Analytical and Biological Chemistry Research Facility, University College Cork, Ireland. stuart.collins@ucc.ie
authors: Stuart G
authors: SG
authors: Collins
authors: Orlagh C M
authors: OC
authors: O'Sullivan
authors: Patrick G
authors: PG
authors: Kelleher
authors: Anita R
authors: AR
authors: Maguire
mesh_terms: D001391:Azo Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D013454:Sulfoxides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001391:Azo Compounds; D013454:Sulfoxides