title: Maleimide-functionalised platinum(IV) complexes as a synthetic platform for targeted drug delivery.
abstract: Maleimide-functionalised Pt(IV) complexes with highly selective binding properties to thiol groups were synthesised as precursors for binding of thiol-containing tumour-targeting molecules like human serum albumin.
authors: University of Vienna, Institute of Inorganic Chemistry, Waehringer Strasse 42, A-1090, Vienna, Austria.
authors: Verena
authors: V
authors: Pichler
authors: University of Vienna, Institute of Inorganic Chemistry, Waehringer Strasse 42, A-1090, Vienna, Austria.
authors: Josef
authors: J
authors: Mayr
authors: Research Platform "Translational Cancer Therapy Research" University of Vienna, Waehringer Strasse 42, A-1090, Vienna, Austria.|Institute of Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, A-1090, Vienna, Austria.
authors: Petra
authors: P
authors: Heffeter
authors: Department of Inorganic and Analytical Chemistry, University of Szeged, Dóm tér 7., H-6720 Szeged, Hungary.
authors: Orsolya
authors: O
authors: Dömötör
authors: Department of Inorganic and Analytical Chemistry, University of Szeged, Dóm tér 7., H-6720 Szeged, Hungary.
authors: Éva A
authors: ÉA
authors: Enyedy
authors: Division of Analytical Chemistry, Department of Chemistry, University of Natural Resources and Applied Life Sciences, Muthgasse 18, A-1190 Vienna, Austria.
authors: Gerrit
authors: G
authors: Hermann
authors: Institute of Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, A-1090, Vienna, Austria.
authors: Diana
authors: D
authors: Groza
authors: Division of Analytical Chemistry, Department of Chemistry, University of Natural Resources and Applied Life Sciences, Muthgasse 18, A-1190 Vienna, Austria.
authors: Gunda
authors: G
authors: Köllensperger
authors: University of Vienna, Institute of Inorganic Chemistry, Waehringer Strasse 42, A-1090, Vienna, Austria.
authors: Markus
authors: M
authors: Galanksi
authors: Research Platform "Translational Cancer Therapy Research" University of Vienna, Waehringer Strasse 42, A-1090, Vienna, Austria.|Institute of Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, A-1090, Vienna, Austria.
authors: Walter
authors: W
authors: Berger
authors: University of Vienna, Institute of Inorganic Chemistry, Waehringer Strasse 42, A-1090, Vienna, Austria.
authors: Bernhard K
authors: BK
authors: Keppler
authors: University of Vienna, Institute of Inorganic Chemistry, Waehringer Strasse 42, A-1090, Vienna, Austria.|Research Platform "Translational Cancer Therapy Research" University of Vienna, Waehringer Strasse 42, A-1090, Vienna, Austria.
authors: Christian R
authors: CR
authors: Kowol
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000473:pathology; D018360:Crystallography, X-Ray; D004305:Dose-Response Relationship, Drug; D016503:Drug Delivery Systems; D006801:Humans; D008301:Maleimides / Q000737:chemistry*; D051379:Mice; D008807:Mice, Inbred BALB C; D008958:Models, Molecular; D015394:Molecular Structure; D009944:Organoplatinum Compounds / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D011355:Prodrugs / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*; D012709:Serum Albumin / Q000032:analysis*; D013329:Structure-Activity Relationship; D013438:Sulfhydryl Compounds / Q000737:chemistry
chemical_list: D000970:Antineoplastic Agents; D008301:Maleimides; D009944:Organoplatinum Compounds; D011355:Prodrugs; D012709:Serum Albumin; D013438:Sulfhydryl Compounds; C043592:maleimide
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