title: Alcohol use behaviors, fat intake and the function of pancreatic β-cells in non-obese, healthy Korean males: findings from 2010 Korea National Health and Nutrition Examination Survey.
abstract: OBJECTIVE
  In the present study, we aimed to identify dietary factors related to insulin secretion function especially in healthy, non-obese Korean males.
  
  
  METHODS
  Data were obtained from the Korea National Health and Nutrition Examination Survey V-1 (KNHANES V-1). Nine hundred and twenty male adults aged >30 years of normal weight were included, excluding those with type 2 diabetes mellitus and liver disease. Alcohol use disorders identification test (AUDIT) score which represents alcohol use behaviors and nutrient intakes was used, and homeostasis model assessment of β-cell function (HOMA-B score) was calculated.
  
  
  RESULTS
  HOMA-B score was associated with age (p < 0.001), AUDIT score (p = 0.030), and percentage of fat from total energy intake (p = 0.002). HOMA-B scores in the problematic AUDIT group were significantly lower than those in the normal AUDIT group. In addition, HOMA-B scores in the lowest fat intake group were significantly lower than those in the medium fat intake group, but similar to those in the highest fat intake group. There was an interaction between alcohol use behaviors and percentage of fat from energy intake in determining HOMA-B score (p for interaction = 0.034).
  
  
  CONCLUSIONS
  Alcohol use behaviors and percentage of fat from energy intake were found to be associated with HOMA-B score in healthy, non-obese Korean males.
authors: Department of Food and Nutrition, Korea University, Seoul, South Korea.
authors: Hye-Kyung
authors: HK
authors: Chung
authors: Yoonsu
authors: Y
authors: Cho
authors: Min-Jeong
authors: MJ
authors: Shin
mesh_terms: D000428:Alcohol Drinking / Q000009:adverse effects*; D044466:Asian People; D015415:Biomarkers / Q000097:blood; D015992:Body Mass Index; D001835:Body Weight; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology / Q000517:prevention & control; D004041:Dietary Fats / Q000008:administration & dosage*; D002149:Energy Intake; D005247:Feeding Behavior; D006706:Homeostasis; D006801:Humans; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D050417:Insulin-Secreting Cells / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D018977:Micronutrients / Q000008:administration & dosage; D008875:Middle Aged; D009749:Nutrition Surveys; D056910:Republic of Korea
chemical_list: D015415:Biomarkers; D004041:Dietary Fats; D007328:Insulin; D018977:Micronutrients