title: Dietary patterns and colorectal cancer recurrence and survival: a cohort study.
abstract: OBJECTIVE
  To examine the association between dietary patterns and colorectal cancer (CRC) survival.
  
  
  METHODS
  Cohort study.
  
  
  METHODS
  A familial CRC registry in Newfoundland.
  
  
  METHODS
  529 newly diagnosed CRC patients from Newfoundland. They were recruited from 1999 to 2003 and followed up until April 2010.
  
  
  METHODS
  Participants reported their dietary intake using a food frequency questionnaire. Dietary patterns were identified with factor analysis. Multivariable Cox proportional hazards models were employed to estimate HR and 95% CI for association of dietary patterns with CRC recurrence and death from all causes, after controlling for covariates.
  
  
  RESULTS
  Disease-free survival (DFS) among CRC patients was significantly worsened among patients with a high processed meat dietary pattern (the highest vs the lowest quartile HR 1.82, 95% CI 1.07 to 3.09). No associations were observed with the prudent vegetable or the high-sugar patterns and DFS. The association between the processed meat pattern and DFS was restricted to patients diagnosed with colon cancer (the highest vs the lowest quartile: HR 2.29, 95% CI 1.19 to 4.40) whereas the relationship between overall survival (OS) and this pattern was observed among patients with colon cancer only (the highest vs the lowest quartile: HR 2.13, 95% CI 1.03 to 4.43). Potential effect modification was noted for sex (p value for interaction 0.04, HR 3.85 for women and 1.22 for men).
  
  
  CONCLUSIONS
  The processed meat dietary pattern prior to diagnosis is associated with higher risk of tumour recurrence, metastasis and death among patients with CRC.
authors: Division of Community Health and Humanities, Faculty of Medicine,  Memorial University of Newfoundland, St. John's, Newfoundland,  Canada.
authors: Yun
authors: Y
authors: Zhu
authors: Hao
authors: H
authors: Wu
authors: Peizhong Peter
authors: PP
authors: Wang
authors: Sevtap
authors: S
authors: Savas
authors: Jennifer
authors: J
authors: Woodrow
authors: Tyler
authors: T
authors: Wish
authors: Rong
authors: R
authors: Jin
authors: Roger
authors: R
authors: Green
authors: Michael
authors: M
authors: Woods
authors: Barbara
authors: B
authors: Roebothan
authors: Sharon
authors: S
authors: Buehler
authors: Elizabeth
authors: E
authors: Dicks
authors: John R
authors: JR
authors: McLaughlin
authors: Peter T
authors: PT
authors: Campbell
authors: Patrick S
authors: PS
authors: Parfrey
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