title: The role of a midpotency topical corticosteroid and the clinical relevance of formulation characteristics in the management of commonly encountered eczematous and inflammatory dermatoses in adults and children: focus on the pharmacologic properties of clocortolone pivalate 0.1% cream.
abstract: Midpotency topical corticosteroids (TCSs) are frequently used for the treatment of common eczematous and inflammatory skin disorders in both adults and children. There are several commercially available products in this category, and many vehicles and formulations for the clinician to choose from. Clocortolone pivalate 0.1% cream is a midpotency TCS formulated in an emollient formulation that has been shown to be effective and well tolerated when used appropriately in the management of several corticosteroid-responsive dermatoses. This article discusses the physiochemical properties of the compound; the characteristics of its emollient cream formulation; the functions of individual excipients; and the efficacy, tolerability, and safety data supporting its use in adults and children, including for facial involvement.
authors: Valley Hospital Medical Center, Las Vegas, NV, USA.
authors: James Q
authors: JQ
authors: Del Rosso
authors: Leon H
authors: LH
authors: Kircik
mesh_terms: D000287:Administration, Topical; D000328:Adult; D002626:Chemistry, Pharmaceutical; D002648:Child; D003877:Dermatitis, Contact / Q000188:drug therapy / Q000473:pathology; D004485:Eczema / Q000188:drug therapy* / Q000473:pathology; D005145:Face; D005448:Fluocortolone / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D009824:Ointments; D011565:Psoriasis / Q000188:drug therapy / Q000473:pathology; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000188:drug therapy* / Q000473:pathology
chemical_list: D005938:Glucocorticoids; D009824:Ointments; D005448:Fluocortolone; C007088:clocortolone pivalate