title: Rhino-orbital mucourmycosis in a non-immunocompromised patient.
abstract: Mucormycosis, also known as phycomycosis or zygomycosis, is caused by common Zygomycete fungi frequently found in soil and decaying vegetation. These mainly infect immunocompromised patients and cause an acute fulminating fungal disease; mucormycosis rarely affects otherwise healthy people. Mucormycosis is a fatal infection with a poor prognosis. Of the different types of mucormycosis, the rhinocerebral type is the most severe one, and its type 2 subtype, the rhino-orbital-cerebral form is the deadliest variety. Here, we report a case of mucormycosis presenting with extensive necrosis of the maxilla with extension into the retrobulbar and infrabulbar region in an otherwise healthy patient. He underwent extensive debriding surgery followed by amphotericin B first and then oral antifungal therapy, but unfortunately, even after extensive surgery and medical treatment, he did not survive.
authors: Department of Neurosurgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. bijoun14@yahoo.com
authors: Asifur
authors: A
authors: Rahman
authors: Khaleda
authors: K
authors: Akter
authors: Shakhawat
authors: S
authors: Hossain
authors: Harun Ur
authors: HU
authors: Rashid
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001850:Bone Diseases, Infectious / Q000628:therapy*; D003646:Debridement; D017809:Fatal Outcome; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008437:Maxilla; D009091:Mucormycosis / Q000628:therapy*; D009668:Nose Diseases / Q000628:therapy*; D009916:Orbital Diseases / Q000628:therapy*; D018461:Soft Tissue Infections / Q000628:therapy*
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B
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