title: [Formation of immune distress syndrome in patients with combined course of chronic obstructive pulmonary disease and chronic pancreatitis].
abstract: The aim of the article was to study the peculiarities of the development of the metabolic intoxication and the formation of autoimmune reactions in patients with combined course of chronic obstructive pulmonary disease (COPD) and chronic pancreatitis. The features of formation metabolic intoxication and autoimmune reactions in patients with combined course of COPD and chronic pancreatitis were revealed. It was found that the presence of concomitant chronic pancreatitis exacerbates the syndrome of endogenous intoxication and the imbalance of regulatory mechanisms of both cellular and humoral immunity significantly increases the risk of autoimmune complications. This fact allows us to consider the presence of concomitant chronic pancreatitis in patients with COPD as unfavorable prognostic factor.
authors: Kharkov State Medical University, Ukraine.
authors: N
authors: N
authors: Zhelezniakova
mesh_terms: D000328:Adult; D000941:Antigens / Q000276:immunology; D001427:Bacterial Toxins / Q000097:blood; D016022:Case-Control Studies; D015897:Comorbidity; D005260:Female; D006801:Humans; D007962:Leukocytes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D050500:Pancreatitis, Chronic / Q000453:epidemiology / Q000276:immunology*; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology / Q000276:immunology*; D013577:Syndrome; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000941:Antigens; D001427:Bacterial Toxins