title: Grating-based darkfield imaging of human breast tissue.
abstract: Mastectomy specimens were investigated using a Talbot-Lau X-ray imaging set-up. Significant structures in the darkfield were observed, which revealed considerably higher contrast than those observed in digital mammography. Comparison with the histomorphometric image proofs that the darkfield signal correlates with a tumor region containing small calcification grains of 3 to 30μm size.
authors: Erlangen Centre for Astroparticle Physics, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erwin-Rommel-Str. 1, 91058 Erlangen, Germany.
authors: Gisela
authors: G
authors: Anton
authors: Florian
authors: F
authors: Bayer
authors: Matthias W
authors: MW
authors: Beckmann
authors: Jürgen
authors: J
authors: Durst
authors: Peter A
authors: PA
authors: Fasching
authors: Wilhelm
authors: W
authors: Haas
authors: Arndt
authors: A
authors: Hartmann
authors: Thilo
authors: T
authors: Michel
authors: Georg
authors: G
authors: Pelzer
authors: Marcus
authors: M
authors: Radicke
authors: Claudia
authors: C
authors: Rauh
authors: Jens
authors: J
authors: Rieger
authors: André
authors: A
authors: Ritter
authors: Rüdiger
authors: R
authors: Schulz-Wendtland
authors: Michael
authors: M
authors: Uder
authors: David L
authors: DL
authors: Wachter
authors: Thomas
authors: T
authors: Weber
authors: Evelyn
authors: E
authors: Wenkel
authors: Lukas
authors: L
authors: Wucherer
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000209:etiology; D002102:Cadaver; D002114:Calcinosis / Q000150:complications / Q000000981:diagnostic imaging*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005240:Feasibility Studies; D006801:Humans; D007368:Interferometry / Q000295:instrumentation / Q000379:methods*; D008327:Mammography / Q000295:instrumentation / Q000379:methods; D012031:Refractometry / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*; D014961:X-Ray Diffraction / Q000295:instrumentation / Q000379:methods*
keywords: Brustkrebs; Dunkelfeldbildgebung; Mammographie; Mikrokalzifikation; Röntgenbildgebung; Talbot-Lau; X-ray imaging; breast cancer; darkfield imaging; mammography; microcalcification