title: Intraoperative radiotherapy in patients with breast cancer treated by breast-conserving therapy.
abstract: OBJECTIVE
  To assess the safety, cosmetic effects, and clinical efficacy of breast-conserving surgery combined with intraoperative radiation therapy for the treatment of Chinese patients with breast cancer.
  
  
  METHODS
  Breast-conserving surgery combined with intraoperative radiation therapy was performed in 64 breast cancer patients. The postoperative short-term efficacy, safety, and cosmetic effects were assessed.
  
  
  RESULTS
  Of the 64 patients, 1 case (1.6%) had local recurrence one year later, 7 cases (10.9%) had grade I postoperative radiation-induced lung injury, 10 cases (15.6%) had local hardening at the surgical sites, 8 cases (12.5 %) had changes in skin color, and 8 cases (12.5%) had pain at the surgical sites. Excellent or good levels of cosmetic effects were achieved in 95.3% of the patients.
  
  
  CONCLUSIONS
  The application of intraoperative radiation therapy with breast-conserving surgery can yield satisfactory short-term curative efficacy, a high level of clinical safety, and good cosmetic effects.
authors: Division of Breast Surgery, Department of General Surgery, General Hospital of Chinese People's Liberation Army, No. 28 Fuxing Rd., Beijing, PR China.
authors: Yan-jun
authors: YJ
authors: Zhang
authors: Lei
authors: L
authors: Liu
authors: Lin
authors: L
authors: Ma
authors: Wei
authors: W
authors: Yu
authors: Mei
authors: M
authors: Liu
authors: Liu-quan
authors: LQ
authors: Cheng
authors: Jie
authors: J
authors: Li
authors: Yi-qiong
authors: YQ
authors: Zheng
authors: Jian-dong
authors: JD
authors: Wang
authors: Qing-long
authors: QL
authors: Kong
authors: Xi-ru
authors: XR
authors: Li
mesh_terms: D000328:Adult; D000368:Aged; D044466:Asian People; D001504:Beauty; D001943:Breast Neoplasms / Q000737:chemistry / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D002277:Carcinoma / Q000532:radiotherapy / Q000601:surgery; D002681:China; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D008168:Lung / Q000528:radiation effects*; D008207:Lymphatic Metastasis; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D009367:Neoplasm Staging; D017060:Patient Satisfaction; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects / Q000379:methods; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D016896:Treatment Outcome
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone