title: Decreasing the diabetic complication by vanadyl(VO)2+/vitamin B 6 complex in alloxan-induced diabetic mice.
abstract: The scope of this work was to synthesize a novel bifunctionalized vanadyl(VO)(2+)/vitamin B 6 complex. The diabetic therapeutic efficacy of the new complex was investigated in alloxan-induced diabetic mice. The results suggested that vanadyl(VO)(2+)/vit B6 complex has an anti-diabetic potency, improved the lipid profile and liver and kidney functions. The new complex possesses an antioxidant activity. The current results support the therapeutic potentiality of vanadyl(VO)(2+)/vitamin B 6 complex for the management of diabetes.
authors: Biology Department, Faculty of Science, Taif University, Qurwa, Taif, Saudi Arabia. elshenawy_nahla@hotmail.com
authors: Nahla S
authors: NS
authors: El-Shenawy
authors: Moamen S
authors: MS
authors: Refat
authors: Fatima H
authors: FH
authors: Fakihi
mesh_terms: D000496:Alloxan; D000818:Animals; D003404:Creatinine / Q000097:blood; D003921:Diabetes Mellitus, Experimental / Q000517:prevention & control*; D005951:Glucose Tolerance Test; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D051379:Mice; D014527:Uric Acid / Q000097:blood; D014638:Vanadates / Q000627:therapeutic use*; D025101:Vitamin B 6 / Q000627:therapeutic use*
chemical_list: D014527:Uric Acid; D014638:Vanadates; D000496:Alloxan; D025101:Vitamin B 6; D003404:Creatinine; D007770:L-Lactate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase
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