title: Nano-hydroxyapatite surfaces grafted with electroactive aniline tetramers for bone-tissue engineering.
abstract: An electroactive amino/carboxyl-capped aniline tetramer (AT) is covalently grafted to the surface of hydroxyapatite (HA) nanoparticles to generate novel electroactive HA-AT nanoparticles. The amount of AT ranges from 16.5 to 34.0 wt% and is characterized by thermogravimetric analysis (TGA). The HA-AT nanoparticles are characterized by Fourier transform IR (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS), X-ray diffraction, and scanning electron microscopy (SEM). For the excellent electroactivity of HA-AT, the mixture of HA-AT and PLA shows much better adhesion ability and proliferation ability than that of HA and a PLA matrix. At a 15 wt% AT grafting amount, the matrix shows the best biocompatibility.
authors: Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
authors: Yadong
authors: Y
authors: Liu
authors: Haitao
authors: H
authors: Cui
authors: Xiuli
authors: X
authors: Zhuang
authors: Peibiao
authors: P
authors: Zhang
authors: Yi
authors: Y
authors: Cui
authors: Xianhong
authors: X
authors: Wang
authors: Yen
authors: Y
authors: Wei
authors: Xuesi
authors: X
authors: Chen
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry*; D000818:Animals; D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000494:pharmacology; D001842:Bone and Bones / Q000166:cytology / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D017886:Durapatite / Q000737:chemistry*; D055664:Electrochemical Techniques; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry*; D010006:Osteoblasts / Q000166:cytology / Q000187:drug effects*; D058105:Polymerization; D012821:Silanes / Q000737:chemistry; D023822:Tissue Engineering
chemical_list: D000814:Aniline Compounds; D001672:Biocompatible Materials; D012821:Silanes; D017886:Durapatite