title: [A case of adenoendocrine cell carcinoma on the ampulla of Vater].
abstract: The occurrence of an adenoendocrine cell carcinoma on the ampulla of Vater is rare, especially when the component of adenocarcinoma is not located on the mucosa of the ampulla. A 76-year-old man was referred to our hospital for further investigation of a mass lesion on the ampulla. EGD revealed SMT like mass lesion on the ampulla. Endoscopic ultrasonography showed an ampullary hypoechoic mass. We performed pylorus-preserving pancreatoduodenectomy on the basis of the diagnosis of poorly differentiated adenocarcinoma of the ampulla of Vater. Postoperative pathological examinations revealed two different components of the tumor;malignant endocrine cells, and adenocarcinoma. The component of adenocarcinoma was located on the Ap lesion. We deducted that the adenocarcinoma appeared on the epithelium of Ap, then grew and spread into the direction of duodenum lumen, degenerating to endocrine cells.
authors: Center for Gastroenterology, Teine Keijinkai Hospital, Japan.
authors: Shin
authors: S
authors: Kato
authors: Hiroyuki
authors: H
authors: Maguchi
authors: Manabu
authors: M
authors: Osanai
authors: Kuniyuki
authors: K
authors: Takahashi
authors: Akio
authors: A
authors: Katanuma
authors: Kei
authors: K
authors: Yane
authors: Shunpei
authors: S
authors: Hashigo
authors: Maki
authors: M
authors: Kaneko
authors: Ryo
authors: R
authors: Harada
authors: Ryusuke
authors: R
authors: Kato
authors: Akiko
authors: A
authors: Tomonari
authors: Yoshiyasu
authors: Y
authors: Ambo
authors: Minoru
authors: M
authors: Takada
authors: Toshiya
authors: T
authors: Shinohara
authors: Akihiro
authors: A
authors: Takiyama
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000368:Aged; D014670:Ampulla of Vater / Q000473:pathology; D003138:Common Bile Duct Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male