title: Teaching enantioselectivity to C-H bond functionalizations: initial steps of a rather long shot.
abstract: The direct functionalization of non-activated C-H bonds, especially in an enantioselective manner, requires metal catalysts equipped with ligands with specifically designed properties. Examples for asymmetric C(sp(2))-H and C(sp(3))-H functionalizations  using palladium- and rhodium catalysts are shown. This work was rewarded by the 2012 Werner Prize of the Swiss Chemical Society.
authors: Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland. nicolai.cramer@epfl.ch
authors: Nicolai
authors: N
authors: Cramer
mesh_terms: D001363:Awards and Prizes; D002384:Catalysis; D002621:Chemistry / Q000193:education*; D015394:Molecular Structure; D009930:Organic Chemicals / Q000138:chemical synthesis / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D012238:Rhodium / Q000737:chemistry; D013237:Stereoisomerism; D013557:Switzerland; D013663:Teaching
chemical_list: D009930:Organic Chemicals; D010165:Palladium; D012238:Rhodium