title: Oxygen therapy in preterm infants.
abstract: Despite being the most widely used and vital therapy in neonatology, optimal strategies for the use of oxygen in preterm infants remain controversial. Achieving the balance between attaining adequate tissue oxygenation and avoiding oxygen toxicity is challenging. There remains a paucity of clear evidence based guidance for clinicians on safe oxygen saturation targets. What does seem apparent is that these targets vary over time in the life of a preterm infant. This article summarises the evidence behind current practice of oxygen monitoring and administration from the first few minutes after birth, through to the acute neonatal and later convalescent periods. Finally, we review the use of home oxygen for preterm infants with bronchopulmonary dysplasia including administration and weaning from domically home oxygen.
authors: Neonatal Intensive Care Unit, University Hospital for Wales, Cardiff CF14 4XW, UK.
authors: S
authors: S
authors: Cherian
authors: Neonatal Intensive Care Unit, University Hospital for Wales, Cardiff CF14 4XW, UK.
authors: I
authors: I
authors: Morris
authors: Neonatal Intensive Care Unit, University Hospital for Wales, Cardiff CF14 4XW, UK.
authors: J
authors: J
authors: Evans
authors: Neonatal Intensive Care Unit, University Hospital for Wales, Cardiff CF14 4XW, UK; Department of Child Health, School of Medicine, Cardiff University,, Cardiff CF14 4XN, UK. Electronic address: kotechas@cardiff.ac.uk.
authors: S
authors: S
authors: Kotecha
mesh_terms: D006699:Home Care Services; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000378:metabolism / Q000628:therapy; D007234:Infant, Premature / Q000378:metabolism; D008991:Monitoring, Physiologic; D010100:Oxygen / Q000378:metabolism; D010102:Oxygen Inhalation Therapy; D013997:Time Factors
chemical_list: D010100:Oxygen
keywords: Bronchopulmonary dysplasia; Continuous positive airway pressure (CPAP); Domiciliary oxygen; High flow oxygen, Neonatal resuscitation; Oxygen saturation monitoring; Preterm, Oxygen therapy