title: [Anti-Mullerian hormone- its role in the pathogenesis of the polycystic ovary syndrome].
abstract: Anti-Mullerian hormone (AMH) is a glycoprotein produced by the granulosa ovarian cells with respect to the regulation of the follicular growth and development. Polycystic ovary syndrome (PCOS) is one of the most common endocrine disturbances affecting 6-7 of women in reproductive age. Women with PCOS exhibit a number of metabolic and endocrine disturbances some of which are paramount in the pathogenesis of PCOS. The studies examining the connection between AMH and PCOS are few and quite controversial. Women with PCOS are considered to have significantly lower levels of AMH as compared with controls which is interpreted as resulting from the greater number of pre-antral follicles, or a result of the specific synthesis of AMH by granulose cells causing follicular arrest in PCOS.
authors: N
authors: N
authors: Parahuleva
authors: B
authors: B
authors: Pehlivanov
authors: E
authors: E
authors: Dimitrakova
authors: M
authors: M
authors: Malinova
authors: M
authors: M
authors: Mladenova
mesh_terms: D054304:Anti-Mullerian Hormone / Q000378:metabolism*; D005260:Female; D006801:Humans; D006080:Ovarian Follicle / Q000378:metabolism / Q000473:pathology; D010053:Ovary / Q000378:metabolism* / Q000473:pathology*; D011085:Polycystic Ovary Syndrome / Q000378:metabolism* / Q000473:pathology*
chemical_list: D054304:Anti-Mullerian Hormone