title: Does aspirin use make it harder to collect seizures during elective video-EEG telemetry?
abstract: Aspirin has shown promise as an anticonvulsant drug in animal models. Whether aspirin alters seizure frequency in humans remains unstudied. We retrospectively looked at adults with focal onset epilepsy who took aspirin daily while undergoing elective video-EEG monitoring and compared them with similar age- and sex-matched controls to see if seizure frequencies were different between those two populations. Significantly fewer seizures were seen on day two of monitoring for patients on aspirin therapies. Higher aspirin doses were correlated with fewer seizures collected during the monitoring stay. Further prospective study is needed to determine whether aspirin affects more robust seizure control.
authors: Department of Psychology, University of California Los Angeles, Los Angeles, CA, USA.
authors: Rachel M
authors: RM
authors: Godfred
authors: Mihir S
authors: MS
authors: Parikh
authors: Alan M
authors: AM
authors: Haltiner
authors: Lisa M
authors: LM
authors: Caylor
authors: Jehuda P
authors: JP
authors: Sepkuty
authors: Michael J
authors: MJ
authors: Doherty
mesh_terms: D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D001241:Aspirin / Q000627:therapeutic use*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012640:Seizures / Q000188:drug therapy* / Q000503:physiopathology; D013686:Telemetry; D016896:Treatment Outcome; D014741:Video Recording
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001241:Aspirin