title: Age, sex, and verbal abilities affect location of linguistic connectivity in ventral visual pathway.
abstract: Previous studies have shown that the strength of connectivity between regions can vary depending upon the cognitive demands of a task. In this study, the location of task-dependent connectivity from the primary visual cortex (V1) was examined in 43 children (ages 9-15) performing visual tasks; connectivity maxima were identified for a visual task requiring a linguistic (orthographic) judgment. Age, sex, and verbal IQ interacted to affect maxima location. Increases in age and verbal IQ produced similar shifts in maxima location; in girls, connectivity maxima shifted primarily laterally within the left temporal lobe, whereas the shift was primarily posterior within occipital cortex among boys. A composite map across all subjects shows an expansion in the area of connectivity with age. Results show that the location of visual/linguistic connectivity varies systematically during development, suggesting that both sex differences and developmental changes in V1 connectivity are related to linguistic function.
authors: Center for Advanced Imaging, NorthShore University HealthSystem, Evanston, IL 60201, USA. DBurman2@northshore.org
authors: Douglas D
authors: DD
authors: Burman
authors: Taylor
authors: T
authors: Minas
authors: Donald J
authors: DJ
authors: Bolger
authors: James R
authors: JR
authors: Booth
mesh_terms: D000293:Adolescent; D041923:Adolescent Development / Q000502:physiology*; D000367:Age Factors; D001931:Brain Mapping; D002648:Child; D002657:Child Development / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012737:Sex Factors; D013702:Temporal Lobe / Q000502:physiology*; D014793:Visual Cortex / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology*
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