title: Prevalence and ethnic distribution of helicobacter pylori infection among endoscoped patients in north eastern peninsular malaysia.
abstract: OBJECTIVE
  The objective of this study was to determine the prevalence and ethnic distribution of Helicobacter pylori infection in an endoscoped population in North Eastern Peninsular Malaysia.
  
  
  METHODS
  Pathology records of 400 consecutive gastric biopsies received at the pathology laboratory in a university hospital were reviewed. Demographic data of patients including their ethnic groups were documented. Evidence of gastritis and H. pylori infection were ascertained by routine histology and Warthin Starry stain. Univariate and multivariate analysis were applied to determine the prevalence of H. pylori infection in the sampled population and the difference in prevalence among the ethnic groups.
  
  
  RESULTS
  The overall H. pylori infection prevalence rate was unusually low at 13.5% (54 of 400) in this region. The prevalence among the races were as follows: Malay 6.6% (17/256), Chinese 24.1% (27/112) and Indian 28.6% (6/21). Gender and age were not significant associated factors for H. pylori infection. However there was an increased risk of H. pylori infection in Chinese (OR= 4.46, 95%CI, 2.3-8.6) and Indians (OR=5.6, 95%CI, 1.9-16.3) compared to Malays.
  
  
  CONCLUSIONS
  The difference in prevalence of H. pylori infection between the three major ethnic groups concurs with other studies done in Malaysia. The reason for this interesting finding is uncertain and is suspected to be due to different environmental, genetic and socio-cultural practices in the various races.
authors: Department of Pathology and.
authors: Gurjeet
authors: G
authors: Kaur
authors: Nyi Nyi
authors: NN
authors: Naing
keywords: Malaysia; ethnic difference; low H. pylori prevalence
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