title: Adult survivors of childhood cancer: the medical and psychosocial late effects of cancer treatment and the impact on sexual and reproductive health.
abstract: BACKGROUND
  There are over 13 million cancer survivors in the United States, which constitutes 3-4% of the U.S. population. According to the Surveillance Epidemiology and End Results program (SEER) data the 5-year overall survival rate for children diagnosed with cancer between ages 0-19 is 83.1%, and 2/3 of childhood cancer survivors will experience at least one late effect of treatment.
  
  
  OBJECTIVE
  To provide a brief overview of the medical and psychosocial effects of cancer treatments in survivors of childhood cancer with a focus on sexual and reproductive health issues in this population.
  
  
  METHODS
  The development of a manuscript from a presentation at the Annual Society of Sexual Medicine meeting. An overview of long-term and late effects of treatment experienced by young adult cancer survivors was presented.
  
  
  METHODS
  This manuscript is based on a presentation that reviewed the medical and psychosocial literature, consensus statements of professional groups, and clinical observations.
  
  
  RESULTS
  Cancer and cancer treatments have both direct and indirect effects of physiological, psychological, and interpersonal factors that can negatively impact the health and well-being of cancer survivors including sexual and reproductive function and satisfaction.
  
  
  CONCLUSIONS
  Cancer, its management, and the resulting late effects must be explored and understood by providers caring for childhood cancer survivors so that educational, psychological, pharmacologic, as well as preventive interventions can be implemented with this population.
authors: Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 19104, USA. a.jacobs@uphs.upenn.edu
authors: Linda A
authors: LA
authors: Jacobs
authors: Donna A
authors: DA
authors: Pucci
mesh_terms: D000328:Adult; D002648:Child; D059247:Fertility Preservation; D006801:Humans; D001523:Mental Disorders / Q000209:etiology / Q000517:prevention & control; D009369:Neoplasms / Q000150:complications / Q000523:psychology / Q000534:rehabilitation*; D060728:Reproductive Health; D019529:Sexuality; D017741:Survivors / Q000523:psychology