title: Effect of blueberry feeding on lipids and oxidative stress in the serum, liver and aorta of guinea pigs fed on a high-cholesterol diet.
abstract: We investigated the effect of blueberries (BB) on lipids and oxidative stress parameters in hypercholesterolemic guinea pigs. The animals were fed for 75 d on a high-cholesterol (HC) diet supplemented with fresh BB. BB reduced oxidative stress and cholesterol accumulation in the aorta and liver of the guinea pigs. This effect may be related to its antioxidative potential and lipid-reducing effect.
authors: Yeditepe University Medical Faculty, Department of Biochemistry, Istanbul, Turkey.
authors: Jale
authors: J
authors: Çoban
authors: Betül
authors: B
authors: Evran
authors: Ferda
authors: F
authors: Özkan
authors: Aydın
authors: A
authors: Çevık
authors: Semra
authors: S
authors: Doğru-Abbasoğlu
authors: Müjdat
authors: M
authors: Uysal
mesh_terms: D000818:Animals; D000924:Anticholesteremic Agents / Q000494:pharmacology; D001011:Aorta / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D029798:Blueberry Plants; D002791:Cholesterol, Dietary / Q000008:administration & dosage*; D059305:Diet, High-Fat; D044948:Flavonols / Q000494:pharmacology; D006168:Guinea Pigs; D006937:Hypercholesterolemia / Q000178:diet therapy* / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D050356:Lipid Metabolism; D015227:Lipid Peroxidation; D008099:Liver / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D008297:Male; D018384:Oxidative Stress; D059808:Polyphenols / Q000494:pharmacology
chemical_list: D000924:Anticholesteremic Agents; D002791:Cholesterol, Dietary; D044948:Flavonols; D059808:Polyphenols