title: Switchable antimicrobial and antifouling hydrogels with enhanced mechanical properties.
abstract: New switchable hydrogels are developed. Under acidic conditions, hydrogels undergo self-cyclization and can catch and kill bacteria. Under neutral/basic conditions, hydrogels undergo ring-opening and can release killed bacterial cells and resist protein adsorption and bacterial attachment. Smart hydrogels also show a dramatically improved mechanical property, which is highly desired for biomedical applications.
authors: Department of Chemical and Biomolecular Engineering, University of Akron, Akron, Ohio 44325, USA.
authors: Bin
authors: B
authors: Cao
authors: Qiong
authors: Q
authors: Tang
authors: Linlin
authors: L
authors: Li
authors: Jayson
authors: J
authors: Humble
authors: Haiyan
authors: H
authors: Wu
authors: Lingyun
authors: L
authors: Liu
authors: Gang
authors: G
authors: Cheng
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry* / Q000494:pharmacology; D002412:Cations / Q000737:chemistry; D003500:Cyclization; D004926:Escherichia coli / Q000187:drug effects; D020100:Hydrogels / Q000737:chemistry* / Q000494:pharmacology; D011108:Polymers / Q000737:chemistry; D013499:Surface Properties
chemical_list: D000890:Anti-Infective Agents; D002412:Cations; D020100:Hydrogels; D011108:Polymers
keywords: antifouling; antimicrobial; hydrogel; lactone; zwitterionic materials