title: [Photodynamic diagnosis and laser biospectroscopy as an intraoperative guidance in neurosurgery].
abstract: Different techniques are used today in neurosurgery for intraoperative navigation, including metabolic guidance using 5-aminolevulinic acid (5-ALA). The article focuses on history of intraoperative photodynamic diagnosis (PDD), mechanisms of 5-ALA action, possibilities of its application in different areas of neurosurgery. In addition to visual assessment of fluorescence, laser biospectroscopy significantly increases the diagnostic value of PDD. Laser biospectroanalysis is described in details, wide perspectives of its application in neurosurgery are demonstrated.
authors: S A
authors: SA
authors: Goriaĭnov
authors: A A
authors: AA
authors: Potapov
authors: D A
authors: DA
authors: Gol'bin
authors: P V
authors: PV
authors: Zelenkov
authors: G L
authors: GL
authors: Kobiakov
authors: A G
authors: AG
authors: Gavrilov
authors: V A
authors: VA
authors: Okhlopkov
authors: V A
authors: VA
authors: Shukhraĭ
authors: E V
authors: EV
authors: Shelesko
authors: V Iu
authors: VIu
authors: Zhukov
authors: V B
authors: VB
authors: Loshchenov
authors: T A
authors: TA
authors: Savel'eva
authors: Kuz'min
mesh_terms: D000622:Aminolevulinic Acid / Q000494:pharmacology*; D006801:Humans; D007834:Lasers; D019635:Neurosurgical Procedures / Q000295:instrumentation* / Q000379:methods*; D061848:Optical Imaging / Q000295:instrumentation / Q000379:methods; D017319:Photosensitizing Agents / Q000494:pharmacology*; D013050:Spectrometry, Fluorescence / Q000295:instrumentation / Q000379:methods
chemical_list: D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid