title: A review on indole alkaloids isolated from Uncaria rhynchophylla and their pharmacological studies.
abstract: Uncaria rhynchophylla (Miq.) Jacks, Rubiaceae, is one of the original plants of the important Chinese crude drug, Gou-teng, mainly used for the treatment of convulsion, hypertension, epilepsy, eclampsia, and cerebral diseases. The pharmacological activities of this plant are related to the presence of active compounds predominantly indole alkaloids. In this article, we have reviewed some reports about the pharmacological activities of the main indole alkaloids isolated from U. rhynchophylla. This review paper will contribute to the studies on the chemistry, safety and quality control of medicinal preparations containing Uncaria species.
authors: Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 88 Yuquan Road, Tianjin 300193, PR China.
authors: Andre
authors: A
authors: Ndagijimana
authors: Xiaoming
authors: X
authors: Wang
authors: Guixiang
authors: G
authors: Pan
authors: Fan
authors: F
authors: Zhang
authors: Hong
authors: H
authors: Feng
authors: Olajide
authors: O
authors: Olaleye
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology*; D000959:Antihypertensive Agents / Q000494:pharmacology*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D026121:Indole Alkaloids / Q000302:isolation & purification / Q000494:pharmacology*; D018696:Neuroprotective Agents / Q000494:pharmacology*; D032070:Uncaria / Q000737:chemistry*
chemical_list: D000927:Anticonvulsants; D000959:Antihypertensive Agents; D004365:Drugs, Chinese Herbal; D026121:Indole Alkaloids; D018696:Neuroprotective Agents; C087631:gou-teng