title: Integrative data analysis in clinical psychology research.
abstract: Integrative data analysis (IDA), a novel framework for conducting the simultaneous analysis of raw data pooled from multiple studies, offers many advantages including economy (i.e., reuse of extant data), power (i.e., large combined sample sizes), the potential to address new questions not answerable by a single contributing study (e.g., combining longitudinal studies to cover a broader swath of the lifespan), and the opportunity to build a more cumulative science (i.e., examining the similarity of effects across studies and potential reasons for dissimilarities). There are also methodological challenges associated with IDA, including the need to account for sampling heterogeneity across studies, to develop commensurate measures across studies, and to account for multiple sources of study differences as they impact hypothesis testing. In this review, we outline potential solutions to these challenges and describe future avenues for developing IDA as a framework for studies in clinical psychology.
authors: Department of Psychology, University of North Carolina at Chapel Hill, North Carolina 27599, USA. hussong@unc.edu
authors: Andrea M
authors: AM
authors: Hussong
authors: Patrick J
authors: PJ
authors: Curran
authors: Daniel J
authors: DJ
authors: Bauer
mesh_terms: D006801:Humans; D015233:Models, Statistical; D011586:Psychology, Clinical / Q000379:methods*; D012107:Research Design / Q000592:standards* / Q000706:statistics & numerical data*
references: Nat Genet. 2007 Oct;39(10):1181-6
references: 17898773
references: Multivariate Behav Res. 2009 Nov 1;44(6):711-740
references: 20411042
references: J Abnorm Child Psychol. 2002 Jun;30(3):199-216
references: 12041707
references: Psychol Methods. 2009 Jun;14(2):101-25
references: 19485624
references: J Abnorm Child Psychol. 2008 Apr;36(3):335-46
references: 17891557
references: Am J Psychiatry. 1999 Jul;156(7):1007-13
references: 10401443
references: J Pediatr Psychol. 2005 Jul-Aug;30(5):377-86
references: 15944165
references: Psychol Methods. 2009 Jun;14(2):165-76
references: 19485627
references: J Abnorm Child Psychol. 2010 Apr;38(3):367-80
references: 20084453
references: Psychol Methods. 2006 Dec;11(4):402-15
references: 17154754
references: Psychol Bull. 1993 Nov;114(3):552-566
references: 8272470
references: J Abnorm Psychol. 2007 Aug;116(3):529-42
references: 17696709
references: Arch Gen Psychiatry. 2012 Jun;69(6):580-7
references: 22309973
references: J Clin Epidemiol. 1999 Apr;52(4):281-91
references: 10235168
references: Psychol Sci Public Interest. 2008 Nov;9(2):i-ii
references: 26162103
references: J Abnorm Psychol. 1991 Nov;100(4):449-63
references: 1757658
references: Dev Psychopathol. 2008 Winter;20(1):165-93
references: 18211733
references: Am Psychol. 2002 Dec;57(12):1060-73
references: 12613157
references: Neuropsychopharmacology. 2002 Jul;27(1):105-19
references: 12062911
references: Am J Epidemiol. 2000 Sep 15;152(6):514-27
references: 10997541
references: Psychol Methods. 2009 Jun;14(2):81-100
references: 19485623
references: Annu Rev Clin Psychol. 2009;5:27-48
references: 18976138
references: N Engl J Med. 1996 Feb 8;334(6):356-61
references: 8538706
references: J Abnorm Child Psychol. 2012 Nov;40(8):1265-76
references: 22886384
references: Monogr Soc Res Child Dev. 1981;46(1):1-82
references: 7242540
references: J Abnorm Psychol. 1991 Nov;100(4):427-48
references: 1757657