title: Usefulness of tumor blood flow imaging by intraoperative indocyanine green videoangiography in hemangioblastoma surgery.
abstract: OBJECTIVE
  Hemangioblastomas remain a surgical challenge because of their arteriovenous malformation-like character. Recently, indocyanine green (ICG) videoangiography has been applied to neurosurgical vascular surgery. The aim of this study was to evaluate the usefulness of tumor blood flow imaging by intraoperative ICG videoangiography in surgery for hemangioblastomas.
  
  
  METHODS
  Twenty intraoperative ICG videoangiography procedures were performed in 12 patients with hemangioblastomas. Seven lesions were located in the cerebellum, two lesions were in the medulla oblongata, and three lesions were in the spinal cord.
  
  
  RESULTS
  Ten procedures were performed before or during dissection, and 10 procedures were performed after tumor resection. ICG videoangiography could provide dynamic images of blood flow in the tumor and its related vessels under surgical view. Interpretation of these dynamic images of tumor blood flow was useful for discrimination of transit feeders (feeders en passage) and also for estimation of unexposed feeders covered with brain parenchyma. Postresection ICG videoangiography could confirm complete tumor resection and normalized blood flow in surrounding vessels.
  
  
  CONCLUSIONS
  In surgery for hemangioblastomas, careful interpretation of dynamic ICG images can provide useful information on transit feeders and unexposed hidden vessels that cannot be directly visualized by ICG.
authors: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan. Electronic address: mhojo@kuhp.kyoto-u.ac.jp.
authors: Masato
authors: M
authors: Hojo
authors: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors: Yoshiki
authors: Y
authors: Arakawa
authors: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors: Takeshi
authors: T
authors: Funaki
authors: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors: Kazumichi
authors: K
authors: Yoshida
authors: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors: Takayuki
authors: T
authors: Kikuchi
authors: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors: Yasushi
authors: Y
authors: Takagi
authors: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors: Yoshio
authors: Y
authors: Araki
authors: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors: Akira
authors: A
authors: Ishii
authors: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors: Takeharu
authors: T
authors: Kunieda
authors: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors: Jun C
authors: JC
authors: Takahashi
authors: Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
authors: Susumu
authors: S
authors: Miyamoto
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000098:blood supply / Q000601:surgery*; D002528:Cerebellar Neoplasms / Q000150:complications / Q000601:surgery; D002533:Cerebral Angiography; D004396:Coloring Agents; D003952:Diagnostic Imaging / Q000379:methods*; D005260:Female; D018325:Hemangioblastoma / Q000098:blood supply / Q000601:surgery*; D006801:Humans; D007208:Indocyanine Green; D064795:Intraoperative Neurophysiological Monitoring; D008297:Male; D008875:Middle Aged; D012039:Regional Blood Flow; D013125:Spinal Neoplasms / Q000098:blood supply / Q000601:surgery*; D055815:Young Adult; D006623:von Hippel-Lindau Disease / Q000150:complications
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green
keywords: Hemangioblastoma; Indocyanine green videoangiography; Transit feeder; Tumor blood flow imaging