title: Anti-atherosclerotic mechanisms of statin therapy.
abstract: HMG-CoA-Reductase inhibitors, also known as statins, are currently the most powerful cholesterol-lowering drugs available on the market. Clinical trials and experimental evidence suggest that statins have anti-atherosclerotic effects. These are in part consequence of lipid lowering but also result from pleiotropic actions of the drugs. In this article, the anti-atherosclerotic actions of statins will be reviewed.
authors: Institut für Kardiovaskuläre Physiologie, Goethe-Universität, Frankfurt, Germany.
authors: Andrea
authors: A
authors: Babelova
authors: Daniel G
authors: DG
authors: Sedding
authors: Ralf P
authors: RP
authors: Brandes
mesh_terms: D000818:Animals; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D006937:Hypercholesterolemia / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors