title: Development of novel biodegradable Au nanocomposite hydrogels based on wheat: for inactivation of bacteria.
abstract: The design and fabrication of novel biodegradable gold nanocomposites hydrogels were developed as antibacterial agent. Biodegradable gold nanocomposite hydrogels were developed by using acrylamide (AM) and wheat protein isolate (WPI). The gold nanoparticles were prepared as a gold colloid by reducing HAuCl(4)·XH(2)O with leaf extracts of Azadirachta indica (neem leaf) that formed hydrogel network. The characterization of developed biodegradable hydrogels were studied using fourier transforms infrared (FTIR) spectroscopy, ultraviolet-visible (UV-vis) spectroscopy, X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), differential scanning calorimetry (DSC), scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) and transmission electron microscopy (TEM). The biodegradable gold nanoparticle composite hydrogels developed were tested for antibacterial properties. The results indicate that these biodegradable gold nanocomposite hydrogels can be used as potential candidates for antibacterial applications.
authors: Synthetic Polymer Laboratory, Department of Polymer Science & Technology, Sri Krishnadevaraya University, Anantapur-515003, India.
authors: Tippabattini
authors: T
authors: Jayaramudu
authors: Gownolla Malegowd
authors: GM
authors: Raghavendra
authors: Kokkarachedu
authors: K
authors: Varaprasad
authors: Rotimi
authors: R
authors: Sadiku
authors: Konduru Mohana
authors: KM
authors: Raju
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D006046:Gold / Q000737:chemistry*; D020100:Hydrogels / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D053768:Metal Nanoparticles / Q000737:chemistry*; D050296:Microbial Viability / Q000187:drug effects*; D053761:Nanocomposites / Q000737:chemistry*; D010940:Plant Proteins / Q000737:chemistry; D013696:Temperature; D014908:Triticum / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D020100:Hydrogels; D010940:Plant Proteins; D006046:Gold