title: Stereo and serial sniffing guide navigation to an odour source in a mammal.
abstract: Integration of bilateral sensory information is fundamental to stimulus localization in auditory systems and depth perception in vision, but the role of stereo olfactory cues remains obscure. Here it is shown that blind, eastern American moles combine serial sampling with bilateral nasal cues to localize odorants. Blocking one nostril causes moles to err in the direction of the open nostril with strongest effect within 4-5 cm of the stimulus. Nostril block does not severely disrupt more distant navigation towards odorants in a T-maze nor prevent animals from ultimately locating the odour source. Crossing inputs to the nostrils using plastic tubes causes a local repulsion from the stimulus, whereas uncrossed tubes do not disrupt localization. These findings show that mammals can make use of bilateral chemosensory cues combined with serial sampling to localize odorants and offer insights into the relative contribution of each strategy during different stages of natural search behaviours.
authors: Department of Biological Sciences, Vanderbilt University, VU Station B, Box 35-1634, Nashville, Tennessee 37235-1634, USA. ken.catania@vanderbilt.edu
authors: Kenneth C
authors: KC
authors: Catania
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D003463:Cues; D008954:Models, Biological; D008971:Moles / Q000502:physiology*; D009296:Nasal Cavity / Q000502:physiology; D009812:Odorants / Q000032:analysis*; D009949:Orientation; D012903:Smell / Q000502:physiology*
references: Physiol Behav. 2009 Jun 22;97(3-4):401-5
references: 19303891
references: Prog Neurobiol. 2011 Nov;95(3):427-47
references: 21963552
references: J Neurophysiol. 1980 Oct;44(4):687-95
references: 7431048
references: Nat Neurosci. 2007 Jan;10(1):27-9
references: 17173046
references: Exp Brain Res. 2010 Aug;205(1):13-29
references: 20603708
references: Nat Neurosci. 2008 Feb;11(2):187-99
references: 18157126
references: Nat Commun. 2012 Feb 28;3:703
references: 22426224
references: J Neurophysiol. 1997 Jul;78(1):160-9
references: 9242270
references: Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12363-8
references: 20616091
references: Brain Behav Evol. 2000 Sep;56(3):146-74
references: 11124516
references: Experientia. 1989 Feb 15;45(2):130-2
references: 2493388
references: Chem Senses. 2009 Feb;34(2):139-44
references: 19001464
references: J Comp Neurol. 1997 Feb 17;378(3):337-53
references: 9034895
references: Front Cell Neurosci. 2010 Mar 31;4:6
references: 20407585
references: J Chem Ecol. 2008 Jul;34(7):837-53
references: 18548311
references: Genome Biol. 2008;9(3):212
references: 18394176
references: Physiol Behav. 1999 Mar;66(1):41-4
references: 10222471
references: Proc Natl Acad Sci U S A. 1972 Sep;69(9):2509-12
references: 4560688
references: Nature. 2005 Feb 3;433(7025):519-22
references: 15690041
references: Curr Opin Neurobiol. 2012 Apr;22(2):243-50
references: 22177596
references: Annu Rev Neurosci. 2003;26:31-55
references: 14527266
references: J Insect Physiol. 1969 Apr;15(4):597-610
references: 5772205
references: Science. 2006 Feb 3;311(5761):666-70
references: 16456082
references: PLoS One. 2011;6(12):e29614
references: 22216331