title: Aqueous synthesis of highly luminescent AgInS₂-ZnS quantum dots and their biological applications.
abstract: Highly emissive and air-stable AgInS2-ZnS quantum dots (ZAIS QDs) with quantum yields of up to 20% have been successfully synthesized directly in aqueous media in the presence of polyacrylic acid (PAA) and mercaptoacetic acid (MAA) as stabilizing and reactivity-controlling agents. The as-prepared water-dispersible ZAIS QDs are around 3 nm in size, possess the tetragonal chalcopyrite crystal structure, and exhibit long fluorescence lifetimes (>100 ns). In addition, these ZAIS QDs are found to exhibit excellent optical and colloidal stability in physiologically relevant pH values as well as very low cytotoxicity, which render them particularly suitable for biological applications. Their potential use in biological labelling of baculoviral vectors is demonstrated.
authors: Institute of Materials Research and Engineering, Agency for Science, Technology and Research, Singapore 117602.
authors: Michelle D
authors: MD
authors: Regulacio
authors: Khin Yin
authors: KY
authors: Win
authors: Seong Loong
authors: SL
authors: Lo
authors: Shuang-Yuan
authors: SY
authors: Zhang
authors: Xinhai
authors: X
authors: Zhang
authors: Shu
authors: S
authors: Wang
authors: Ming-Yong
authors: MY
authors: Han
authors: Yuangang
authors: Y
authors: Zheng
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry; D016367:Baculoviridae / Q000737:chemistry; D056945:Hep G2 Cells; D006801:Humans; D007204:Indium / Q000737:chemistry* / Q000494:pharmacology; D045663:Quantum Dots; D018030:Silver Compounds / Q000737:chemistry* / Q000494:pharmacology; D013194:Staining and Labeling / Q000379:methods; D013440:Sulfides / Q000737:chemistry* / Q000494:pharmacology; D013864:Thioglycolates / Q000737:chemistry; D017967:Zinc Compounds / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000180:Acrylic Resins; D018030:Silver Compounds; D013440:Sulfides; D013864:Thioglycolates; D017967:Zinc Compounds; D007204:Indium; C006903:carbopol 940; C017487:2-mercaptoacetate; C013251:silver sulfide; C031238:zinc sulfide