title: Prostate cancer: The androgen receptor remains front and centre.
authors: Division of Hematology-Oncology, Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, 55 Fruit Street, Yawkey 7E, Boston, MA 02114, USA. psaylor@partners.org.
authors: Philip J
authors: PJ
authors: Saylor
mesh_terms: D000069501:Abiraterone Acetate; D000230:Adenocarcinoma / Q000188:drug therapy*; D000726:Androgen Antagonists / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D000728:Androgens / Q000096:biosynthesis; D000730:Androstadienes / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017326:Clinical Trials, Phase III as Topic / Q000706:statistics & numerical data*; D018572:Disease-Free Survival; D000077143:Docetaxel; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D008297:Male; D058990:Molecular Targeted Therapy; D015337:Multicenter Studies as Topic / Q000706:statistics & numerical data*; D009363:Neoplasm Proteins / Q000502:physiology*; D009376:Neoplasms, Hormone-Dependent / Q000188:drug therapy*; D011241:Prednisone / Q000008:administration & dosage; D011471:Prostatic Neoplasms / Q000188:drug therapy*; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data*; D011944:Receptors, Androgen / Q000502:physiology*; D013254:Steroid 17-alpha-Hydroxylase / Q000037:antagonists & inhibitors; D015996:Survival Rate; D043823:Taxoids / Q000627:therapeutic use
chemical_list: D000726:Androgen Antagonists; D000728:Androgens; D000730:Androstadienes; D018931:Antineoplastic Agents, Hormonal; D000972:Antineoplastic Agents, Phytogenic; D004791:Enzyme Inhibitors; D009363:Neoplasm Proteins; D011944:Receptors, Androgen; D043823:Taxoids; D000077143:Docetaxel; D013254:Steroid 17-alpha-Hydroxylase; D000069501:Abiraterone Acetate; D011241:Prednisone
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