title: Five percent weight lost in the first month of intragastric balloon treatment may be a predictor for long-term weight maintenance.
abstract: BACKGROUND
  Most of the weight loss with the BioEnterics intragastric balloon (BIB) has occurred during the first 3-4 months. This study aimed to evaluate the effect of initial weight loss on long-term weight maintenance.
  
  
  METHODS
  From 2008 to 2011, 50 patients who had mean body mass index (BMI) of 44.7 ± 12.4 kg/m(2) underwent BIB therapy for 6 months. All patients were given a diet of 1,100 kcal/day. Weight loss parameters [absolute weight loss, BMI loss, percentage of body weight loss (BWL%), and percentage of excess BMI loss] were recorded at the baseline, 1 month, 6 months (time of BIB removal), 12 months, and 18 months from the baseline. Successful weight loss was defined as ≥ 10 % weight loss after 6, 12, and 18 months.
  
  
  RESULTS
  Twenty-seven patients (54 %) achieved a percentage of BWL ≥ 10 at the time of removal. Eighteen (36 %) and 12 (24 %) patients were able to maintain weight loss of 10 % at 12 and 18 months. Percentage of BWL after 1 month was positively correlated with BWL% after 6, 12, and 18 months (r = 0.77, 0.65, and 0.62, p < 0.001, respectively). Twenty-four patients who lost 5 % of the BWL after 1 month of treatment succeeded in maintaining a lasting percentage of BWL ≥ 10 after the BIB removal: more precisely, this cutoff point was achieved in 96 % at the time of removal and in 71 %, 50 % at 12 months, and 18 months of follow-up.
  
  
  CONCLUSIONS
  Five percent BWL after 1 month of treatment may be a predictor for long-term weight maintenance.
authors: Department of Gastroenterology, Adana Numune Training and Research Hospital, Adana, Turkey. ubdogan@hotmail.com
authors: Umit Bilge
authors: UB
authors: Dogan
authors: Yuksel
authors: Y
authors: Gumurdulu
authors: Mustafa Salih
authors: MS
authors: Akin
authors: Serkan
authors: S
authors: Yalaki
mesh_terms: D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D020878:Device Removal; D005260:Female; D005500:Follow-Up Studies; D015905:Gastric Balloon; D015438:Health Behavior; D006801:Humans; D008297:Male; D008875:Middle Aged; D009042:Motivation; D009767:Obesity, Morbid / Q000453:epidemiology / Q000601:surgery*; D010349:Patient Compliance / Q000706:statistics & numerical data*; D018579:Patient Selection; D011446:Prospective Studies; D055502:Secondary Prevention; D012720:Severity of Illness Index; D013997:Time Factors; D016896:Treatment Outcome; D014421:Turkey / Q000453:epidemiology; D015431:Weight Loss
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