title: IMDAF/aromatization path of halogenated furylacrylamides and furylpropiolamides to dihydroisoquinolin-1(2H)-ones.
abstract: Intramolecular Diels-Alder cycloadditions of chlorofuryl- (R = Cl) secondary (R' = H) acrylamides and propiolamides of type 1 followed by (optional modification and) base-induced aromatization of the resulting chlorinated oxanorborn(adi)enes 2 afford N-free-dihydroisoquinolin-1(2H)-ones 3 with different aromatic substitution patterns.
authors: Department of Organic Chemistry, University of Santiago de Compostela, Campus Vida sn, 15782 Santiago de Compostela, A Coruña, Spain.
authors: Olaia
authors: O
authors: Nieto-García
authors: Ricardo
authors: R
authors: Alonso
mesh_terms: D000178:Acrylamides / Q000737:chemistry*; D061565:Cycloaddition Reaction; D005663:Furans / Q000737:chemistry*; D054879:Halogenation; D007546:Isoquinolines / Q000737:chemistry*; D015394:Molecular Structure; D011422:Propionates / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000178:Acrylamides; D005663:Furans; D007546:Isoquinolines; D011422:Propionates