title: Macular lymphocytic arteritis: first clinical presentation with ulcers.
abstract: Macular lymphocytic arteritis describes a recently reported entity, clinically characterized by asymptomatic hyperpigmented macules on the lower limbs, without association of systemic diseases. Histopathologically it is characterized by a lymphocytic arteritis with a hyalinized fibrin ring. We report a new case presenting with ulceration, a finding not previously described. A 25-year-old Hispanic woman was evaluated for a 1-year history of a gradually progressive, asymptomatic eruption that begins at level of both knees and progressively affects both legs and feet. She also referred recently appeared ulcers on inner right ankle without previous traumatism. Physical examination revealed multiple fairly well-defined light brown and faint pink patches with petechiae on as well as retiform crusts and livedoid lesions on inner right ankle. Both types of lesions were biopsied showing lymphocytic arteritis with fibrinoid necrosis and thrombus. There were no relevant laboratory alterations. The clinical peculiarity of our case is the clinical image of the lesions mimicking a pigmented purpuric dermatosis and the presence of a non-traumatic ulcer which could be explained because chronic lymphocytic damage may cause ischemic damage. Ulceration in our case supports consideration of macular arteritis as a latent form of cutaneous polyarteritis nodosa.
authors: Department of Dermatology, Hospital Universitario de La Princesa, Madrid, Spain. mar.llamasvelasco@gmail.com
authors: M
authors: M
authors: Llamas-Velasco
authors: P
authors: P
authors: García-Martín
authors: J
authors: J
authors: Sánchez-Pérez
authors: E
authors: E
authors: Sotomayor
authors: J
authors: J
authors: Fraga
authors: A
authors: A
authors: García-Diez
mesh_terms: D000328:Adult; D001167:Arteritis / Q000473:pathology*; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000473:pathology*; D010859:Pigmentation Disorders / Q000473:pathology; D010488:Polyarteritis Nodosa / Q000473:pathology*; D011693:Purpura / Q000473:pathology; D012867:Skin / Q000098:blood supply; D017445:Skin Diseases, Vascular / Q000473:pathology*; D012883:Skin Ulcer / Q000473:pathology*