title: Serotonin syndrome manifesting as patient movement during total intravenous anesthesia with propofol and remifentanil.
abstract: A patient who manifested signs of serotonin syndrome during an intravenous anesthetic with remifentanil and propofol is presented. The patient displayed lower extremity clonus, nystagmus, and diaphoresis. At the time of surgery, the patient was being treated with fluoxetine (a selective serotonin reuptake inhibitor). A presumptive diagnosis of serotonin syndrome was made intraoperatively and all opioids were discontinued. His symptoms resolved in the Postanesthesia Care Unit without incident.
authors: Department of Anesthesiology, University of Utah, Salt Lake City, UT 84132, USA. Jennifer.Davis@hsc.utah.edu
authors: Jennifer J
authors: JJ
authors: Davis
authors: Nathan S
authors: NS
authors: Buck
authors: Jeffrey D
authors: JD
authors: Swenson
authors: Ken B
authors: KB
authors: Johnson
authors: Patrick E
authors: PE
authors: Greis
mesh_terms: D000771:Anesthesia, Intravenous / Q000379:methods*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D005473:Fluoxetine / Q000009:adverse effects; D006801:Humans; D007431:Intraoperative Complications / Q000139:chemically induced / Q000175:diagnosis*; D008297:Male; D009068:Movement / Q000187:drug effects; D009207:Myoclonus / Q000139:chemically induced; D010880:Piperidines / Q000008:administration & dosage*; D015742:Propofol / Q000008:administration & dosage*; D000077208:Remifentanil; D020230:Serotonin Syndrome / Q000175:diagnosis* / Q000209:etiology; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects; D055815:Young Adult
chemical_list: D018686:Anesthetics, Intravenous; D005473:Fluoxetine; D010880:Piperidines; D015742:Propofol; D000077208:Remifentanil; D017367:Selective Serotonin Reuptake Inhibitors