title: Total synthesis of kottamide E.
abstract: The first synthesis of kottamide E, a marine natural product containing a 5,6-dibromoindole linked via a (Z)-enamide to an unusual 1,2-dithiolane-containing amino acid, is reported.
authors: School of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
authors: Thomas B
authors: TB
authors: Parsons
authors: Neil
authors: N
authors: Spencer
authors: Chi W
authors: CW
authors: Tsang
authors: Richard S
authors: RS
authors: Grainger
mesh_terms: D000596:Amino Acids / Q000138:chemical synthesis / Q000737:chemistry*; D026121:Indole Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D007211:Indoles / Q000737:chemistry; D008063:Thioctic Acid / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: C448825:1,2-dithiolane; D000596:Amino Acids; D026121:Indole Alkaloids; D007211:Indoles; C583012:kottamide E; C012382:indole-3-carboxylic acid; D008063:Thioctic Acid; C030374:indole