title: [The monitoring role of otoacoustic emission and oxidative stress markers in the protective effects of antioxidant administration in noise-exposed subjects: a pilot study].
abstract: The aims of this study is to assess how DPOAEs can discriminate normal subjects with a risk of damage induced by noise, the effectiveness of OAEs in monitoring the effect of Q-Ter, and the role of blood tests to monitor therapy. In the placebo group, the amplitude of DPOAEs was reduced 1 hour and 16 hours after exposure, the group treated with Q-Ter showed normal DPOAEs. This pilot study confirms that DPOAEs represent a sensitive test for monitoring the effects of noise in preclinical conditions and pharmacological treatment.
authors: Prima Clinica ORL, dipartimento di Fisiopatologia Clinica, Università di Torino, Via Genova 3, 100126 Torino, Italy.
authors: F
authors: F
authors: Revello
authors: S
authors: S
authors: Defilippi
authors: G
authors: G
authors: Meinardi
authors: L
authors: L
authors: Raimondo
authors: M
authors: M
authors: Garzaro
authors: C
authors: C
authors: Giordano
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use*; D015415:Biomarkers; D004784:Environmental Monitoring / Q000379:methods*; D006801:Humans; D008297:Male; D009623:Noise, Occupational / Q000009:adverse effects*; D017084:Otoacoustic Emissions, Spontaneous; D018384:Oxidative Stress; D010865:Pilot Projects; D055815:Young Adult
chemical_list: D000975:Antioxidants; D015415:Biomarkers