title: Cost-effective and rapid blood analysis on a cell-phone.
abstract: We demonstrate a compact and cost-effective imaging cytometry platform installed on a cell-phone for the measurement of the density of red and white blood cells as well as hemoglobin concentration in human blood samples. Fluorescent and bright-field images of blood samples are captured using separate optical attachments to the cell-phone and are rapidly processed through a custom-developed smart application running on the phone for counting of blood cells and determining hemoglobin density. We evaluated the performance of this cell-phone based blood analysis platform using anonymous human blood samples and achieved comparable results to a standard bench-top hematology analyser. Test results can either be stored on the cell-phone memory or be transmitted to a central server, providing remote diagnosis opportunities even in field settings.
authors: Electrical Engineering Department, University of California, Los Angeles, CA 90095, USA.
authors: Hongying
authors: H
authors: Zhu
authors: Ikbal
authors: I
authors: Sencan
authors: Justin
authors: J
authors: Wong
authors: Stoyan
authors: S
authors: Dimitrov
authors: Derek
authors: D
authors: Tseng
authors: Keita
authors: K
authors: Nagashima
authors: Aydogan
authors: A
authors: Ozcan
mesh_terms: D001772:Blood Cell Count / Q000191:economics* / Q000295:instrumentation*; D001774:Blood Chemical Analysis / Q000191:economics* / Q000295:instrumentation*; D002452:Cell Count; D040421:Cell Phone; D003362:Cost-Benefit Analysis; D004906:Erythrocyte Count; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007958:Leukocyte Count; D019095:Point-of-Care Systems; D013997:Time Factors
chemical_list: D006454:Hemoglobins
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