title: Leprosy with ANA positive mistaken for connective tissue disease.
abstract: Leprosy is associated with the occurrence of various skin lesions such as macules, papules, plaques, nodules, and even diffused infiltration, depending on the patient's immune response. Its clinical presentation is often different from the usual pattern, leading to confusion in diagnosis. We present a case of leprosy with ANA positive that was mistaken for connective tissue disease. In this case, we want to tell that doctors should not only depend on laboratory index for diagnosis, the misdiagnosis may lead to delaying illness and aggravating illness.
authors: Department of family medicine, Sir Run Run Shaw Hospital, Zhejiang University, Qingchun Road No.3, Hangzhou 310016, China. chaoguanqun@medmail.com.cn
authors: Guanqun
authors: G
authors: Chao
authors: Lizheng
authors: L
authors: Fang
authors: Chongrong
authors: C
authors: Lu
mesh_terms: D000974:Antibodies, Antinuclear / Q000097:blood*; D001706:Biopsy; D003240:Connective Tissue Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D004487:Edema / Q000175:diagnosis; D005260:Female; D006801:Humans; D006987:Hypesthesia / Q000175:diagnosis; D007918:Leprosy / Q000175:diagnosis*; D008875:Middle Aged; D012883:Skin Ulcer / Q000175:diagnosis
chemical_list: D000974:Antibodies, Antinuclear
references: Clin Microbiol Rev. 2006 Apr;19(2):338-81
references: 16614253
references: Int J Dermatol. 1996 Jun;35(6):389-92
references: 8737869
references: Rev Soc Bras Med Trop. 2003 Jan-Feb;36(1):57-64
references: 12715064
references: Int J Rheum Dis. 2009 Apr;12(1):64-9
references: 20374320
references: Rheumatology (Oxford). 2007 Apr;46(4):653-6
references: 17077158
references: Wkly Epidemiol Rec. 2009 Aug 14;84(33):333-40
references: 19685606
references: Lepr Rev. 2007 Mar;78(1):50-1
references: 17518093
references: Lepr Rev. 2003 Jun;74(2):154-62
references: 12862257
references: South Med J. 2004 Dec;97(12):1252-6
references: 15646765