title: An allele of Arabidopsis COI1 with hypo- and hypermorphic phenotypes in plant growth, defence and fertility.
abstract: Resistance to biotrophic pathogens is largely dependent on the hormone salicylic acid (SA) while jasmonic acid (JA) regulates resistance against necrotrophs. JA negatively regulates SA and is, in itself, negatively regulated by SA. A key component of the JA signal transduction pathway is its receptor, the COI1 gene. Mutations in this gene can affect all the JA phenotypes, whereas mutations in other genes, either in JA signal transduction or in JA biosynthesis, lack this general effect. To identify components of the part of the resistance against biotrophs independent of SA, a mutagenised population of NahG plants (severely depleted of SA) was screened for suppression of susceptibility. The screen resulted in the identification of intragenic and extragenic suppressors, and the results presented here correspond to the characterization of one extragenic suppressor, coi1-40. coi1-40 is quite different from previously described coi1 alleles, and it represents a strategy for enhancing resistance to biotrophs with low levels of SA, likely suppressing NahG by increasing the perception to the remaining SA. The phenotypes of coi1-40 lead us to speculate about a modular function for COI1, since we have recovered a mutation in COI1 which has a number of JA-related phenotypes reduced while others are equal to or above wild type levels.
authors: Instituto de Biología Molecular y Celular de Plantas (IBMCP), Universidad Politécnica de Valencia (UPV)-Consejo Superior de Investigaciones Científicas (CSIC), Ciudad Politécnica de la Innovación (CPI), Valencia, Spain.
authors: Albor
authors: A
authors: Dobón
authors: Brande B H
authors: BB
authors: Wulff
authors: Juan Vicente
authors: JV
authors: Canet
authors: Patrocinio
authors: P
authors: Fort
authors: Pablo
authors: P
authors: Tornero
mesh_terms: D000483:Alleles; D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development / Q000382:microbiology / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000235:genetics*; D003517:Cyclopentanes / Q000494:pharmacology; D004268:DNA-Binding Proteins / Q000235:genetics*; D060467:Disease Resistance / Q000187:drug effects / Q000235:genetics*; D005298:Fertility / Q000187:drug effects / Q000235:genetics; D018506:Gene Expression Regulation, Plant / Q000187:drug effects; D016296:Mutagenesis; D054883:Oxylipins / Q000494:pharmacology; D010641:Phenotype; D016958:Pseudomonas putida / Q000502:physiology; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D029681:Arabidopsis Proteins; C092776:CONSTANS protein, Arabidopsis; D003517:Cyclopentanes; D004268:DNA-Binding Proteins; D054883:Oxylipins; D014157:Transcription Factors; C011006:jasmonic acid
references: Plant Cell. 2009 Mar;21(3):954-71
references: 19329558
references: Plant Cell. 2002 Feb;14(2):435-50
references: 11884685
references: Planta. 2002 Aug;215(4):549-56
references: 12172836
references: Science. 1994 Nov 18;266(5188):1247-50
references: 17810266
references: Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7819-24
references: 9636234
references: Mol Plant Microbe Interact. 1995 May-Jun;8(3):444-53
references: 7655064
references: Plant Cell. 1998 Sep;10(9):1571-80
references: 9724702
references: Plant Cell. 2003 May;15(5):1083-94
references: 12724535
references: Trends Plant Sci. 1999 Feb;4(2):52-58
references: 10234273
references: Environ Microbiol. 2005 Sep;7(9):1339-48
references: 16104857
references: Development. 2009 Mar;136(6):1039-48
references: 19234066
references: Plant J. 2001 Jun;26(5):509-22
references: 11439137
references: Plant Cell. 2009 May;21(5):1495-511
references: 19435934
references: J Exp Bot. 2009;60(13):3849-60
references: 19596700
references: Plant Cell. 1997 Sep;9(9):1573-84
references: 9338960
references: Plant Cell. 1996 Feb;8(2):251-257
references: 12239384
references: Plant J. 2001 Jan;25(1):67-77
references: 11169183
references: Science. 1998 May 15;280(5366):1091-4
references: 9582125
references: Trends Plant Sci. 1999 Dec;4(12):503-507
references: 10562736
references: Virology. 1961 Jul;14:340-58
references: 13743578
references: Plant Physiol. 2003 Nov;133(3):1367-75
references: 14551332
references: Cell. 1997 Jan 10;88(1):57-63
references: 9019406
references: Annu Rev Phytopathol. 2009;47:177-206
references: 19400653
references: Plant Cell Physiol. 2012 Jan;53(1):53-63
references: 22156383
references: Plant Physiol. 1996 Jun;111(2):525-531
references: 12226307
references: Plant Cell. 2001 Apr;13(4):843-52
references: 11283340
references: Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):1075-80
references: 17215350
references: Plant Physiol. 2008 Jul;147(3):1279-87
references: 18451262
references: Plant Physiol. 2005 Jun;138(2):1083-96
references: 15923334
references: Nucleic Acids Res. 2003 Jul 1;31(13):3497-500
references: 12824352
references: Curr Opin Plant Biol. 2009 Oct;12(5):539-47
references: 19716757
references: Nucleic Acids Res. 2008 Jan;36(Database issue):D1009-14
references: 17986450
references: PLoS Genet. 2012;8(10):e1003018
references: 23093946
references: Curr Opin Plant Biol. 2007 Aug;10(4):372-9
references: 17646123
references: Cell. 1994 Sep 23;78(6):1089-99
references: 7923358
references: Plant Cell. 2009 Aug;21(8):2220-36
references: 19717617
references: Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1791-6
references: 15657122
references: Plant Mol Biol. 1995 Mar;27(5):933-42
references: 7766883
references: Plant Biotechnol J. 2010 Feb;8(2):126-41
references: 20040060
references: Plant Cell. 2000 Dec;12(12):2383-2394
references: 11148285
references: Science. 2005 May 13;308(5724):1036-40
references: 15890886
references: Plant J. 2001 Nov;28(4):475-81
references: 11737784
references: Curr Opin Plant Biol. 2002 Aug;5(4):325-31
references: 12179966
references: Plant Physiol. 2002 Mar;128(3):876-84
references: 11891244
references: Plant J. 2004 Apr;38(1):119-30
references: 15053765
references: Proc Natl Acad Sci U S A. 1995 Jul 3;92(14):6597-601
references: 11607554
references: Science. 1995 Aug 11;269(5225):843-6
references: 7638602
references: Plant Cell. 1994 May;6(5):751-759
references: 12244256
references: Plant Cell Environ. 2010 Nov;33(11):1911-22
references: 20561252
references: Plant J. 1991 Nov;1(3):289-302
references: 21736648
references: Plant Cell. 2005 Jul;17(7):2123-37
references: 15923348
references: Plant J. 1996 Jul;10(1):71-82
references: 8758979
references: Genes Dev. 1995 Sep 1;9(17):2131-42
references: 7657165
references: Genetics. 2000 Nov;156(3):1349-62
references: 11063707
references: Nature. 2001 Nov 29;414(6863):562-5
references: 11734859
references: New Phytol. 2010 Sep;187(4):1018-1033
references: 20636323
references: Plant Cell. 2002 Aug;14(8):1919-35
references: 12172031
references: Science. 1993 Aug 6;261(5122):754-6
references: 17757215
references: Genomics. 1994 Jan 1;19(1):137-44
references: 8188214
references: Mol Plant Microbe Interact. 1995 Nov-Dec;8(6):863-70
references: 8664495
references: J Exp Bot. 2011 Jun;62(10):3321-38
references: 21357767
references: Nature. 2007 Aug 9;448(7154):666-71
references: 17637675
references: EMBO Rep. 2009 Aug;10(8):923-8
references: 19575013
references: Mol Plant Microbe Interact. 1995 Jan-Feb;8(1):165-71
references: 7539639
references: Cell. 1994 May 20;77(4):565-77
references: 8187176
references: Plant Methods. 2008 Dec 31;4:28
references: 19117519
references: Plant Cell. 1994 Dec;6(12):1845-57
references: 7866028
references: Plant J. 2002 Jan;29(1):11-21
references: 12060223
references: Plant Cell. 2001 Feb;13(2):437-47
references: 11226196
references: Planta. 2011 Oct;234(4):671-84
references: 21614499
references: Plant J. 1993 Aug;4(2):403-10
references: 8106085