title: Use of Macrolane VRF 30 in emicircumferential penis enlargement.
abstract: BACKGROUND
  Penis enlargement is increasingly in demand. Methods for penis enlargement can be classified into surgical, nonsurgical (filling), and mechanical. Each method has shown only relatively successful results. A new formulation of injectable, stabilized, hyaluronic acid (HA)-based, nonanimal gel is available that may have applications for this use.
  
  
  OBJECTIVE
  The authors propose a new technique for emicircumferential-injection filling of the penis and assess the safety and efficacy of this procedure compared with lipofilling.
  
  
  METHODS
  The authors retrospectively reviewed the charts of 83 patients who underwent penis enlargement with either their HA-injection technique or lipofilling between December 2007 and July 2011. Safety, efficacy, and patient satisfaction were assessed.
  
  
  RESULTS
  The circumferential enlargement obtained from both techniques ranged from 3.2 to 4.5 cm, with a decrement during erection. In all patients, the increase in penis length ranged from 1.8 to 3.6 cm. No complications were seen in patients treated with HA, whereas 8 patients treated with lipofilling developed granuloma, and another experienced fat necrosis. The vast majority (n = 72) of patients reported being "very satisfied" with the results.
  
  
  CONCLUSIONS
  The ideal technique for penis enlargement should be nonsurgical, with a satisfactory and predictable result, a low rate of complications, and long-term stability. Emicircumferential enlargement with HA filler meets these requirements. However, results have been durable but not definitive, and repeated treatment (with associated costs) is necessary.
authors: Department of Plastic Surgery, University Federico II, Naples, Italy.
authors: Giuseppe
authors: G
authors: Sito
authors: Sergio
authors: S
authors: Marlino
authors: Adriano
authors: A
authors: Santorelli
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D000328:Adult; D003357:Cosmetic Techniques / Q000009:adverse effects; D005218:Fat Necrosis / Q000453:epidemiology; D005500:Follow-Up Studies; D005782:Gels; D006099:Granuloma / Q000453:epidemiology; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage*; D008297:Male; D017060:Patient Satisfaction; D010413:Penis / Q000601:surgery*; D012189:Retrospective Studies
chemical_list: D005782:Gels; D006820:Hyaluronic Acid