title: Mesenchymal autologous stem cells.
abstract: The use of cell-based therapies for spinal cord injuries has recently gained prominence as a potential therapy or component of a combination strategy. Experimental and clinical studies have been performed using mesenchymal stem cell therapy to treat spinal cord injuries with encouraging results. However, there have been reports on the adverse effects of these stem cell-based therapies, especially in the context of tumor modulation. This article surveys the literature relevant to the potential of mesenchymal autologous stem cells for spinal cord injuries and their clinical implications.
authors: Department of Neurosurgery, Medical School of the University of Caxias do Sul, Caxias do Sul, Brazil. Electronic address: asdrubalmd@gmail.com.
authors: Asdrubal
authors: A
authors: Falavigna
authors: Neurology Service and Instituto do Cérebro, Pontifical Catholic University of Rio Grande do Sul, Brazil.
authors: Jaderson Costa
authors: JC
authors: da Costa
mesh_terms: D000818:Animals; D064987:Cell- and Tissue-Based Therapy / Q000379:methods; D006801:Humans; D045164:Mesenchymal Stem Cell Transplantation / Q000009:adverse effects / Q000379:methods; D059630:Mesenchymal Stem Cells; D013119:Spinal Cord Injuries / Q000601:surgery*
keywords: Cell transplantation; Clinical translations; Mesenchymal stem cells; Neuronal differentiation; Spinal cord injury