title: Patient-specific finite element modeling for femoral bone augmentation.
abstract: The aim of this study was to provide a fast and accurate finite element (FE) modeling scheme for predicting bone stiffness and strength suitable for use within the framework of a computer-assisted osteoporotic femoral bone augmentation surgery system. The key parts of the system, i.e. preoperative planning and intraoperative assessment of the augmentation, demand the finite element model to be solved and analyzed rapidly. Available CT scans and mechanical testing results from nine pairs of osteoporotic femur bones, with one specimen from each pair augmented by polymethylmethacrylate (PMMA) bone cement, were used to create FE models and compare the results with experiments. Correlation values of R(2)=0.72-0.95 were observed between the experiments and FEA results which, combined with the fast model convergence (~3 min for ~250,000 degrees of freedom), makes the presented modeling approach a promising candidate for the intended application of preoperative planning and intraoperative assessment of bone augmentation surgery.
authors: Laboratory for Computational Sensing & Robotics, Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA. basafa@jhu.edu
authors: Ehsan
authors: E
authors: Basafa
authors: Robert S
authors: RS
authors: Armiger
authors: Michael D
authors: MD
authors: Kutzer
authors: Stephen M
authors: SM
authors: Belkoff
authors: Simon C
authors: SC
authors: Mears
authors: Mehran
authors: M
authors: Armand
mesh_terms: D001696:Biomechanical Phenomena; D005269:Femur / Q000502:physiology* / Q000601:surgery*; D020342:Finite Element Analysis; D006801:Humans; D008422:Materials Testing; D057285:Precision Medicine; D025321:Surgery, Computer-Assisted; D013997:Time Factors
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