title: At-risk brain tissue identified with arterial spin labeling in neurotuberculosis.
abstract: A 13-year-old immunocompromised girl developed neurotuberculosis. Arterial spin labeling technique indicated areas of hypoperfusion in the vascular territories of the left posterior cerebral artery and superior cerebellar artery without restricted diffusion, suggesting early tuberculous arteritis. MR angiography confirmed vascular involvement, so adjunctive anticoagulant therapy was initiated. Complete resolution of arterial spin labeling findings was observed 1 month later. This documents early tuberculous vasculopathy revealed by arterial spin labeling in a child with neurotuberculosis. Since there may be a paucity of clinical symptoms in the evolution of arteritis in neurotuberculosis, arterial spin labeling may help indicate early hypoperfusion and alert for modification of treatment before irreversible vascular damage occurs.
authors: Department of Pediatric Radiology, University Hospital Vall d'Hebron, Barcelona, Spain. persamarga@yahoo.gr
authors: Persefoni
authors: P
authors: Margariti
authors: Angel
authors: A
authors: Sanchez-Montanez
authors: Ignacio
authors: I
authors: Delgado
authors: Izaskun
authors: I
authors: Elorza Alvarez
authors: Elida
authors: E
authors: Vazquez
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology*; D002539:Cerebral Arterial Diseases / Q000473:pathology*; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods; D013113:Spin Labels; D014381:Tuberculosis, Cardiovascular / Q000473:pathology*; D020306:Tuberculosis, Central Nervous System / Q000473:pathology*
chemical_list: D013113:Spin Labels
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