title: Differences in the development of autogenous nerves between the upper and lower urinary tract.
abstract: The aim of this study was to observe the development and distribution of autogenous nerves in the urinary tract of New Zealand rabbits. Animals of various ages were used in this study, including 2, 3 and 3.5 weeks (gestational ages) and 1, 4, 8 and 12 weeks (postnatal). Samples were selected at various sites of the urinary tract. Immunohistochemical staining methods were used to investigate the nervous plexus and neuroganglia on the wall of the urinary tract. Myenteric plexuses and ganglia first appeared at the gestational age of 3 weeks. They decreased in the pelvis and ureter as the animals developed, until at the end of postnatal week 8, all nerves disappeared completely. However, nerves existed in the bladder and posterior urethra permanently. The development and distribution of myenteric nerves is different between the upper and lower part of the urinary tract. Our study aimed to investigate this further.
authors: Department of Urology, Shanghai Children's Medical Center affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200127;
authors: Qimin
authors: Q
authors: Chen
authors: Jinquan
authors: J
authors: Cai
authors: Chengren
authors: C
authors: Shi
authors: Jie
authors: J
authors: Sun
authors: Minzhi
authors: M
authors: Yin
authors: Ping
authors: P
authors: Shen
keywords: development; nervous plexus; neuroganglion; urinary tract
references: J Pediatr Surg. 1989 Jan;24(1):83-6; discussion 86-7
references: 2724000
references: J Neurochem. 2012 Sep;122(5):872-82
references: 22776024
references: J Vis Exp. 2012 Jul 26;(65):
references: 22872172
references: Arch Ital Urol Androl. 2011 Sep;83(3):128-32
references: 22184836
references: Aktuelle Urol. 2005 Aug;36(4):317-28
references: 16110405
references: Neurourol Urodyn. 2007 Oct;26(6 Suppl):904-7
references: 17663416
references: Semin Cell Dev Biol. 2003 Aug;14(4):217-24
references: 14627120
references: Nihon Hinyokika Gakkai Zasshi. 1992 Nov;83(11):1759-66
references: 1479748
references: J Auton Nerv Syst. 1988 Nov;25(1):41-7
references: 3225381
references: J Smooth Muscle Res. 2005 Jun;41(3):117-32
references: 16006745
references: Dev Growth Differ. 2007 May;49(4):277-86
references: 17501905
references: Vet Clin North Am Small Anim Pract. 2008 May;38(3):503-12, ix
references: 18402877
references: Nat Rev Neurosci. 2007 Jun;8(6):466-79
references: 17514199
references: Korean J Urol. 2012 May;53(5):355-9
references: 22670196
references: Acta Physiol Scand. 1995 Sep;155(1):31-9
references: 8553875
references: Rom J Morphol Embryol. 2008;49(1):63-7
references: 18273505
references: Ann Pathol. 2004 Oct;24(5):407-15
references: 15738866
references: Int J Urol. 2011 May;18(5):341-9
references: 21443728
references: Urologe A. 2007 Dec;46(12):1643-6
references: 17999044
references: Neurogastroenterol Motil. 2009 Feb;21(2):113-27
references: 19215589
references: Kidney Int. 2009 Jun;75(11):1153-1165
references: 19340092
references: Intern Med. 2000 May;39(5):355-61
references: 10830173