title: Effectiveness of seasonal 2012/13 vaccine in preventing laboratory-confirmed influenza infection in primary care in the United Kingdom: mid-season analysis 2012/13.
abstract: The early experience of the United Kingdom (UK) is that influenza B has dominated the influenza 2012/13 season. Overall trivalent influenza vaccine (TIV) adjusted vaccine effectiveness (VE) against all laboratory-confirmed influenza in primary care was 51% (95% confidence interval (CI): 27% to 68%); TIV adjusted VE against influenza A alone or influenza B alone was 49% (95% CI: -2% to 75%) and 52% (95% CI: 23% to 70%) respectively. Vaccination remains the best protection against influenza.
authors: Health Protection Scotland, Glasgow, United Kingdom. jim.mcmenamin@nhs.net
authors: J
authors: J
authors: McMenamin
authors: N
authors: N
authors: Andrews
authors: C
authors: C
authors: Robertson
authors: Dm
authors: D
authors: Fleming
authors: H
authors: H
authors: Durnall
authors: B
authors: B
authors: von Wissmann
authors: J
authors: J
authors: Ellis
authors: A
authors: A
authors: Lackenby
authors: S
authors: S
authors: Cottrell
authors: B
authors: B
authors: Smyth
authors: M
authors: M
authors: Zambon
authors: C
authors: C
authors: Moore
authors: Jm
authors: J
authors: Watson
authors: Rg
authors: R
authors: Pebody
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009980:Influenza A virus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D009981:Influenza B virus / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000276:immunology; D007251:Influenza, Human / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011320:Primary Health Care; D060888:Real-Time Polymerase Chain Reaction; D012621:Seasons; D018571:Sentinel Surveillance; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D006113:United Kingdom / Q000453:epidemiology; D014611:Vaccination / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D007252:Influenza Vaccines