title: Optimisation of internal radiation dose assessment on uncertain dosimetric parameters in interpretation of bioassay results.
abstract: Estimates of the committed effective dose (E50) from an intake of a radionuclide strongly depends on several dosimetric parameters such as the intake pathway, f1 value, the absorption type, activity median aerodynamic diameter and the time after an intake. A misuse of the dosimetric parameters can result in a significant error in the evaluated value of a committed effective dose. In order to reduce the potential error and to get optimised values of E50, better bioassay methods and better (or worse) bioassay measurement times due to the uncertain dosimetric parameters were suggested for the various radionuclides, including (57)Co, (58)Co, (60)Co, (131)I, (134)Cs, (137)Cs, (89)Sr, (90)Sr, (32)P and (235)U. This strategy was applied for the case of multiple unknown parameters as well as a single unknown parameter and provided the committed effective doses with the least potential error.
authors: Korea Atomic Energy Research Institute, PO Box 105, Yuseong-gu, Daejeon, Republic of Korea. jilee2@kaeri.re.kr
authors: Jongil
authors: J
authors: Lee
authors: Jaiki
authors: J
authors: Lee
authors: Siyoung
authors: S
authors: Chang
authors: Janglyul
authors: J
authors: Kim
mesh_terms: D001681:Biological Assay; D001822:Body Burden; D006801:Humans; D011829:Radiation Dosage; D011835:Radiation Protection; D011868:Radioisotopes; D011874:Radiometry; D018570:Risk Assessment
chemical_list: D011868:Radioisotopes