title: [Immunocytochemical identification of synaptotagmin 1, syntaxin 1, N-type Ca(2+)-channel and nicotinic cholinoreceptor in motor neuromuscular junctions of earthworm somatic muscle Lumbricus terrestris].
abstract: The somatic muscle of earthworm contains myoneural synapses forming clusters of "synaptic buttons". In these "buttons", the proteins syntaxin 1, synaptotagmin 1 and alpha 1B subunit of the Ca(2+)-channel of N-type were identified. We suppose that "synaptic buttons" contain a limited number of active zones due to their small size (1-2 microm) and the pattern of distribution of proteins of exo-endocytotic cycle. The postsynaptic membrane of cholinetgic synapses contains nicotinic acetylcholine receptors capable to bind alpha-bungarotoxin. The area of location of receptors on postsynaptic membrane is strictly limited to the region of synaptic contact.
authors: M E
authors: ME
authors: Volkov
authors: E M
authors: EM
authors: Volkov
authors: L F
authors: LF
authors: Narullin
mesh_terms: D000818:Animals; D002038:Bungarotoxins / Q000378:metabolism; D020864:Calcium Channels, N-Type / Q000302:isolation & purification / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D009469:Neuromuscular Junction / Q000378:metabolism; D009835:Oligochaeta / Q000378:metabolism; D011978:Receptors, Nicotinic / Q000302:isolation & purification / Q000378:metabolism; D013569:Synapses / Q000378:metabolism; D013570:Synaptic Membranes / Q000378:metabolism; D050863:Synaptotagmin I / Q000302:isolation & purification / Q000378:metabolism; D050827:Syntaxin 1 / Q000302:isolation & purification / Q000378:metabolism
chemical_list: D002038:Bungarotoxins; D020864:Calcium Channels, N-Type; D011978:Receptors, Nicotinic; D050863:Synaptotagmin I; D050827:Syntaxin 1