title: Correlation between peripheral blood pressure and pulse-wave velocity values in the institutionalized elderly persons 80 years of age and older: the PARTAGE study.
abstract: BACKGROUND
  Carotid-femoral pulse-wave velocity (PWV) provides a comprehensive noninvasive indication of arterial stiffness, and is now established as a strong marker of cardiovascular disease (CVD). The correlation between peripheral blood pressure (BP) and PWV and their respective influences on mortality have been poorly studied in the elderly. Our objective was to analyze this correlation in nursing-home residents over 80 years of age, with the view that the results of this could ultimately be helpful in implementing strategies for the diagnosis and long-term follow-up of CVD and mortality in the very elderly population.
  
  
  METHODS
  The Predictive Value of Blood Pressure and Arterial Stiffness in Institutionalized Very Aged Population (PARTAGE) study is a 2-year cohort study of 1,130 subjects living in 72 nursing homes in France and Italy. The correlation between baseline systolic and diastolic blood pressure (SBP and DBP, respectively) and baseline PWV (measured with a PulsePen® tonometer) was studied in 1,071 subjects for whom PWV measurements were available.
  
  
  RESULTS
  Correlations between peripheral BP and PWV were significant but weak, with r = 0.24 for self-measured SBP, r = 0.30 for casual SBP, r = 0.11 for self-measured DBP, r = 0.14 for casual DBP, and r = 0.26 for casual pulse pressure (PP). A trend toward a weaker correlation was observed in the older age group for self-measured SBP and in the group with a lower level of activities of daily living (ADL) for self-measured SBP and DBP.
  
  
  CONCLUSIONS
  These findings suggest that SBP, DBP, and PWV provide different information in the very elderly. The results of the prospective, longitudinal, long-term PARTAGE study will allow further insight into this and provide additional in-depth information about the respective prognostic value of the measurement of peripheral BP and PWV.
authors: Université de Lorraine, Nancy, France.
authors: Darko
authors: D
authors: Miljkovic
authors: Christine
authors: C
authors: Perret-Guillaume
authors: François
authors: F
authors: Alla
authors: Paolo
authors: P
authors: Salvi
authors: Marie-Line
authors: ML
authors: Erpelding
authors: Athanase
authors: A
authors: Benetos
mesh_terms: D000367:Age Factors; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology*; D002318:Cardiovascular Diseases / Q000453:epidemiology; D002339:Carotid Arteries / Q000502:physiology*; D015331:Cohort Studies; D005260:Female; D005263:Femoral Artery / Q000502:physiology*; D005602:France; D006801:Humans; D007558:Italy; D008137:Longitudinal Studies; D008297:Male; D009735:Nursing Homes; D011237:Predictive Value of Tests; D011446:Prospective Studies; D063177:Pulse Wave Analysis; D012307:Risk Factors; D012737:Sex Factors; D059289:Vascular Stiffness / Q000502:physiology*
chemical_list: D000959:Antihypertensive Agents