title: Palladium-catalyzed coupling of polyfluorinated arenes with heteroarenes via C-F/C-H activation.
abstract: The first palladium-catalyzed coupling of 2-pyridyl-polyfluoroarenes and benzoxazole, thiazole, benzothiazole, benzoimidazole, oxazole or oxadiazole via a concurrent C-F/C-H activation is described. Initial mechanistic studies showed that C-F activation of perfluoroarene is likely the rate-limiting step of the catalytic cycle. This protocol provides a useful and operationally simple process to functionalized polyfluoroarenes.
authors: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, People's Republic of China.
authors: Daohong
authors: D
authors: Yu
authors: Long
authors: L
authors: Lu
authors: Qilong
authors: Q
authors: Shen