title: Surface-protein interactions on different stainless steel grades: effects of protein adsorption, surface changes and metal release.
abstract: Implantation using stainless steels (SS) is an example where an understanding of protein-induced metal release from SS is important when assessing potential toxicological risks. Here, the protein-induced metal release was investigated for austenitic (AISI 304, 310, and 316L), ferritic (AISI 430), and duplex (AISI 2205) grades in a phosphate buffered saline (PBS, pH 7.4) solution containing either bovine serum albumin (BSA) or lysozyme (LSZ). The results show that both BSA and LSZ induce a significant enrichment of chromium in the surface oxide of all stainless steel grades. Both proteins induced an enhanced extent of released iron, chromium, nickel and manganese, very significant in the case of BSA (up to 40-fold increase), whereas both proteins reduced the corrosion resistance of SS, with the reverse situation for iron metal (reduced corrosion rates and reduced metal release in the presence of proteins). A full monolayer coverage is necessary to induce the effects observed.
authors: Division of Surface and Corrosion Science, Department of Chemistry, School of Chemical Science and Engineering, KTH Royal Institute of Technology, Stockholm, Sweden. yolanda@kth.se
authors: Y
authors: Y
authors: Hedberg
authors: X
authors: X
authors: Wang
authors: J
authors: J
authors: Hedberg
authors: M
authors: M
authors: Lundin
authors: E
authors: E
authors: Blomberg
authors: I Odnevall
authors: IO
authors: Wallinder
mesh_terms: D000327:Adsorption; D008670:Metals / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*; D013193:Stainless Steel; D013499:Surface Properties
chemical_list: D008670:Metals; D011506:Proteins; D013193:Stainless Steel
references: Part Fibre Toxicol. 2010 Sep 03;7:23
references: 20815895
references: Regul Toxicol Pharmacol. 2013 Feb;65(1):135-46
references: 23142754
references: J Mater Sci Mater Med. 2012 Mar;23(3):657-66
references: 22271277
references: J Mater Sci Mater Med. 2010 Feb;21(2):675-83
references: 19826928
references: J Biol Chem. 1963 Aug;238:2698-707
references: 14063294
references: J Environ Monit. 2008 Sep;10(9):1084-91
references: 18728902
references: Biophys Chem. 2005 Oct 3;117(3):217-24
references: 15963625
references: Environ Sci Process Impacts. 2013 Feb;15(2):381-92
references: 25208703
references: Biometals. 2011 Dec;24(6):1099-114
references: 21691833
references: Biomaterials. 2005 Jan;26(1):11-21
references: 15193877
references: J Dairy Sci. 1998 Oct;81(10):2765-70
references: 9812282
references: Biomaterials. 2001 Aug;22(16):2215-28
references: 11456061
references: Clin Chim Acta. 1974 Dec 17;57(3):205-9
references: 4434640
references: Biochem Biophys Res Commun. 1990 Dec 14;173(2):639-46
references: 2260975
references: Acta Biomater. 2006 Nov;2(6):709-15
references: 16935040
references: J Mater Sci Mater Med. 2006 Oct;17(10):911-8
references: 16977388
references: Langmuir. 2011 Apr 19;27(8):4721-7
references: 21443169
references: J Environ Monit. 2008 Sep;10(9):1092-8
references: 18728903
references: J Colloid Interface Sci. 2012 Jan 15;366(1):155-164
references: 22014396
references: J Mater Sci Mater Med. 2003 Jan;14(1):69-77
references: 15348541
references: Langmuir. 2012 Nov 27;28(47):16306-17
references: 23116183
references: Langmuir. 2011 Mar 15;27(6):2747-60
references: 21338116
references: Integr Environ Assess Manag. 2010 Jul;6(3):441-55
references: 20821706
references: J Environ Monit. 2007 Jan;9(1):74-81
references: 17213945
references: J Biomed Mater Res A. 2008 Apr;85(1):167-75
references: 17688266
references: Biomaterials. 2004 Dec;25(28):5913-20
references: 15183605
references: J Biomed Mater Res. 1984 Jan;18(1):99-114
references: 6699034
references: Acta Biomater. 2012 Sep;8(9):3478-90
references: 22522009
references: Langmuir. 2010 Jan 5;26(1):249-59
references: 19697905
references: Integr Environ Assess Manag. 2010 Jul;6(3):456-68
references: 20821707
references: Adv Protein Chem. 1985;37:161-245
references: 3904348
references: Nature. 1992 Jul 16;358(6383):209-15
references: 1630489