title: Synthesis of cyclopentadiene-fused chromanones via one-pot multicomponent reactions.
abstract: We have developed one-pot method for the synthesis of functionalized novel cyclopentadiene-fused chromanone scaffolds. A variety of 4-oxo-2,4-dihydrocyclopenta[c]chromene-1,2-dicarboxylates were obtained in moderate to good yields via condensation of 2-hydroxybenzaldehydes and ethyl acetoacetate with 1:1 acetylenecarboxylate-isocyanides in toluene. These reactions presumably proceed via reaction of the in situ generated 3-acetyl-2H-chromen-2-ones with acetylenecarboxylate-isocyanide zwitterionic intermediates through Michael addition/intramolecular cyclization and double [1,5] acyl shift rearrangement cascade.
authors: School of Chemistry, College of Science, University of Tehran, P.O. Box 14155, Tehran 6455, Iran. ghandi@khayam.ut.ac.ir
authors: Mehdi
authors: M
authors: Ghandi
authors: Ali-Tabatabaei
authors: AT
authors: Ghomi
authors: Maciej
authors: M
authors: Kubicki