title: Review: Endothelial progenitor cells in pregnancy and obstetric pathologies.
abstract: Since their discovery, endothelial progenitor cells (EPCs) have generated considerable interest in vascular biology. They are a heterogeneous population of cells that exist in both the fetus and adult, and are mobilized to support de novo vessel formation or encourage vascular health. This review summarizes our understanding of these cells in pregnancy, paying particular attention to their physiological role in placental development and the uterus, alongside their involvement in related obstetric pathologies.
authors: Faculty of Medical and Human Sciences, University of Manchester, Maternal and Fetal Health Research Centre, Institute of Human Development, Manchester, UK. Ian.Crocker@manchester.ac.uk
authors: I P
authors: IP
authors: Crocker
authors: P I
authors: PI
authors: Sipos
mesh_terms: D000328:Adult; D000818:Animals; D042783:Endothelial Cells / Q000502:physiology*; D005260:Female; D005333:Fetus / Q000166:cytology / Q000502:physiology; D006801:Humans; D010920:Placenta / Q000166:cytology / Q000502:physiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D013234:Stem Cells / Q000502:physiology*; D014599:Uterus / Q000166:cytology / Q000502:physiology