title: ELECANS--an integrated model development environment for multiscale cancer systems biology.
abstract: BACKGROUND
  Computational multiscale models help cancer biologists to study the spatiotemporal dynamics of complex biological systems and to reveal the underlying mechanism of emergent properties.
  
  
  RESULTS
  To facilitate the construction of such models, we have developed a next generation modelling platform for cancer systems biology, termed 'ELECANS' (electronic cancer system). It is equipped with a graphical user interface-based development environment for multiscale modelling along with a software development kit such that hierarchically complex biological systems can be conveniently modelled and simulated by using the graphical user interface/software development kit combination. Associated software accessories can also help users to perform post-processing of the simulation data for visualization and further analysis. In summary, ELECANS is a new modelling platform for cancer systems biology and provides a convenient and flexible modelling and simulation environment that is particularly useful for those without an intensive programming background.
  
  
  METHODS
  ELECANS, its associated software accessories, demo examples, documentation and issues database are freely available at http://sbie.kaist.ac.kr/sub_0204.php.
  
  
  BACKGROUND
  Supplementary data are available at Bioinformatics online.
authors: Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 305-701, Republic of Korea.
authors: Safee Ullah
authors: SU
authors: Chaudhary
authors: Sung-Young
authors: SY
authors: Shin
authors: Daewon
authors: D
authors: Lee
authors: Je-Hoon
authors: JH
authors: Song
authors: Kwang-Hyun
authors: KH
authors: Cho
mesh_terms: D003198:Computer Simulation; D006801:Humans; D008954:Models, Biological; D009369:Neoplasms / Q000378:metabolism*; D012984:Software; D049490:Systems Biology / Q000379:methods