title: Management of gestational hypertension - the impact of HYPITATa.
abstract: OBJECTIVE
  The objective of this study was to examine the impact of one trial (the HYPITAT trial) on management of gestational hypertension.
  
  
  METHODS
  This is a retrospective cohort study of 5077 patients delivered at our institution from 7/1/2008 to 6/15/2011. "Pre-HYPITAT" was defined as 7/1/2008-9/30/2009 and "Post-HYPITAT" as 10/1/2009-6/15/2011. The primary outcome is the rate of delivery intervention for gestational hypertension. Secondary maternal and neonatal outcomes were analyzed in patients with gestational hypertension only. Statistical analyses included the χ2-test, Fisher's exact test, and the two-sample t-test.
  
  
  RESULTS
  The rate of delivery intervention Pre-HYPITAT was 1.9%, compared to 4% Post-HYPITAT (P<0.001). There was no significant change in secondary outcomes.
  
  
  CONCLUSIONS
  There was a statistically significant increase in delivery intervention for gestational hypertension at our institution after the publication of the HYPITAT trial. There was no significant change in immediate maternal or neonatal outcomes for patients with gestational hypertension.
authors: Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Penn State University College of Medicine, The Milton S. Hershey Medical Center, Hershey, PA 17033, USA. jpauli@hmc.psu.edu
authors: Jaimey M
authors: JM
authors: Pauli
authors: Julianne R
authors: JR
authors: Lauring
authors: Christy M
authors: CM
authors: Stetter
authors: John T
authors: JT
authors: Repke
authors: John J
authors: JJ
authors: Botti
authors: Serdar H
authors: SH
authors: Ural
authors: Anthony
authors: A
authors: Ambrose
mesh_terms: D000328:Adult; D002585:Cesarean Section; D015331:Cohort Studies; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000628:therapy*; D007231:Infant, Newborn; D007751:Labor, Induced; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D055815:Young Adult