title: Cardiac stem cell senescence.
abstract: Cellular senescence processes affecting tissue resident stem cells are considered, at present, an hallmark of both aging and age-related pathologies. Therefore it is mandatory to address this problem with adequate techniques that could highlight the molecular alterations associated with this complex cellular response to stressors. Here we describe methods to characterize cardiac stem cell (CSC) senescence from a molecular and functional standpoint.
authors: Department of Medical and Biological Sciences, University of Udine, Udine, Italy. daniela.cesselli@uniud.it
authors: Daniela
authors: D
authors: Cesselli
authors: Federica
authors: F
authors: D'Aurizio
authors: Patrizia
authors: P
authors: Marcon
authors: Natascha
authors: N
authors: Bergamin
authors: Carlo Alberto
authors: CA
authors: Beltrami
authors: Antonio Paolo
authors: AP
authors: Beltrami
mesh_terms: D049109:Cell Proliferation; D002478:Cells, Cultured; D016922:Cellular Senescence / Q000502:physiology*; D005434:Flow Cytometry / Q000379:methods*; D005455:Fluorescent Antibody Technique / Q000379:methods*; D006321:Heart / Q000502:physiology*; D006801:Humans; D017348:Microscopy, Electron, Scanning Transmission; D013234:Stem Cells / Q000166:cytology* / Q000502:physiology