title: [Percutaneous left atrial appendage closure after resolution of left atrial appendage thrombi with dabigatran].
abstract: The "gold standard" of the prevention of atrial fibrillation related thromboembolic events is anticoagulation therapy with oral vitamin K antagonists. A certain proportion of high-risk patients with atrial fibrillation are not receiving effective antithrombotic therapy because of problems associated with its use. Resolution of subsequent left atrial appendage thrombi is quite a great challenge in patients who are not tolerating "standard" antithrombotic drugs. According to the knowledge of the authors, this is the first report of a patient with non-valvular persistent atrial fibrillation and high stroke risk, who was intolerant to "standard" anticoagulant therapy and had persistent left atrial appendage thrombi following the use of a wide variety of "standard" anticoagulants. Successful resolution of left atrial appendage thrombi with dabigatran and successful percutaneous left atrial appendage closure were performed in this case.
authors: Gottsegen György Országos Kardiológiai Intézet Felnőtt Kardiológia Budapest. iszusz11@freemail.hu
authors: Zsuzsanna
authors: Z
authors: Kis
authors: Csaba
authors: C
authors: Földesi
authors: Mátyás
authors: M
authors: Pál
authors: Zoltán
authors: Z
authors: Som
authors: Andrea
authors: A
authors: Csillik
authors: Pál
authors: P
authors: Abrahám
authors: András
authors: A
authors: Temesvári
authors: Géza
authors: G
authors: Fontos
authors: András
authors: A
authors: Szatmári
authors: Péter
authors: P
authors: Andréka
authors: Attila
authors: A
authors: Kardos
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage; D000991:Antithrombins / Q000627:therapeutic use*; D017073:Atherectomy; D020517:Atrial Appendage / Q000000981:diagnostic imaging / Q000473:pathology; D001281:Atrial Fibrillation / Q000000981:diagnostic imaging / Q000628:therapy*; D001562:Benzimidazoles / Q000627:therapeutic use*; D015897:Comorbidity; D000069604:Dabigatran; D017548:Echocardiography, Transesophageal; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage; D006801:Humans; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications; D012307:Risk Factors; D020521:Stroke / Q000517:prevention & control; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D016896:Treatment Outcome; D015091:beta-Alanine / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D000991:Antithrombins; D001562:Benzimidazoles; D006495:Heparin, Low-Molecular-Weight; D015091:beta-Alanine; D000069604:Dabigatran