title: Glioblastoma: approach to treat elderly patients.
abstract: Treating elderly cancer patients is a challenge for oncologists, especially considering the several therapeutic modalities in glioblastoma. Extensive tumor resection offers the best chance of local control. Adequate radiotherapy should always be given to elderly patients if they have undergone gross total resection and have maintained a good performance status. Rather than being ruled out, chemotherapy should be considered, and temozolomide is the chosen drug. A comprehensive geriatric assessment is a valuable tool to help guiding treatment decisions in elderly patients with glioblastoma.
authors: Department of Clinical Oncology, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
authors: Luciola de Barros
authors: Lde B
authors: Pontes
authors: Theodora
authors: T
authors: Karnakis
authors: Suzana Maria Fleury
authors: SM
authors: Malheiros
authors: Eduardo
authors: E
authors: Weltman
authors: Reynaldo André
authors: RA
authors: Brandt
authors: Rafael Aliosha Kaliks
authors: RA
authors: Guendelmann
mesh_terms: D000367:Age Factors; D000368:Aged; D019175:DNA Methylation; D015577:Geriatric Assessment; D005909:Glioblastoma / Q000235:genetics / Q000628:therapy*; D006801:Humans; D011401:Promoter Regions, Genetic; D016896:Treatment Outcome