title: Inhibition of self-grooming induced by sleep restriction in dam rats.
abstract: OBJECTIVE
  Sleep restriction is a common feature of modern lifestyle and its effects can be extended to pregnancy. Several neurobehavioural consequences of sleep restriction during pregnancy have been reported, among which stand out perinatal depression and maternal fatigue, however, its effects over mother-infant relationship warrant further investigation. Thus, this study was aimed to evaluate the effects of sleep restriction during pregnancy over maternal behaviour and maternal aggression through animal models.
  
  
  METHODS
  Eighteen 90-day-old female Wistar rats were distributed in two groups: (i) Control - not submitted to any manipulation during pregnancy, and (ii) Sleep restriction - submitted to sleep restriction during the entire pregnancy (21 days) through the multiple platforms technique. In the postpartum day 5, resident-intruder paradigm and the latencies test were performed to assess both maternal behaviour and maternal aggression.
  
  
  RESULTS
  The sleep-restricted females displayed grooming in less frequency and duration, and with higher latency when compared to normal animals, while maternal aggression and maternal behaviour parameters remained equivalent between groups.
  
  
  CONCLUSIONS
  Considering the maintenance of maternal behavioural parameters, the inhibition of grooming seems to exert an adaptive mechanism, enabling sleep-restricted rats to display maternal behaviour properly.
authors: Department of Psychobiology-Universidede Federal São Paulo-São, Paulo, Brazil.
authors: Gabriel Natan
authors: GN
authors: Pires
authors: Tathiana Aparecida
authors: TA
authors: Alvarenga
authors: Lucas Oliveira
authors: LO
authors: Maia
authors: Renata
authors: R
authors: Mazaro-Costa
authors: Sergio
authors: S
authors: Tufik
authors: Monica Levy
authors: ML
authors: Andersen
mesh_terms: D000374:Aggression / Q000523:psychology*; D000818:Animals; D016022:Case-Control Studies; D005260:Female; D006120:Grooming / Q000502:physiology*; D007837:Latency Period, Psychological; D008425:Maternal Behavior / Q000523:psychology*; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D012892:Sleep Deprivation / Q000150:complications*
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