title: Clinical significance of jejunoileal involvement of non-Hodgkin's lymphoma detected by double-balloon enteroscopy.
abstract: Jejunoileal involvement of non-Hodgkin's lymphoma (NHL) is an important diagnostic factor in determining optimal treatment strategies. Here, we used double-balloon enteroscopy (DBE) to detect jejunoileal involvement of NHL and studied its clinical significance in a series of patients with NHL. Adults aged between 18 and 85 years with infiltration of the stomach, duodenum, or colon confirmed by gastrointestinal endoscopy or colonoscopy, suspected jejunoileal involvement determined by CT or FDG-PET, or any other gastrointestinal symptoms, were eligible for inclusion in the study. Among 428 patients with histologically confirmed NHL between 2004 and 2011, 83 were eligible for DBE, but 20 patients were excluded due to rejection or poor clinical status. Thus, 63 underwent DBE. The 3-year overall survival rate was significantly lower in patients with (n = 33), than without (n = 30) jejunoileal involvement of NHL confirmed by DBE (49 vs. 92 %, p < 0.005). Four participants developed aspiration pneumonia, but recovered after treatment with antibiotics.
authors: First Department of Internal Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
authors: Takashi
authors: T
authors: Ibuka
authors: Hisashi
authors: H
authors: Tsurumi
authors: Hiroshi
authors: H
authors: Araki
authors: Takeshi
authors: T
authors: Hara
authors: Fumito
authors: F
authors: Onogi
authors: Naoe
authors: N
authors: Goto
authors: Yasushi
authors: Y
authors: Kojima
authors: Nobuhiro
authors: N
authors: Kanemura
authors: Makoto
authors: M
authors: Shiraki
authors: Senji
authors: S
authors: Kasahara
authors: Masahito
authors: M
authors: Shimizu
authors: Kengo
authors: K
authors: Ogawa
authors: Soranobu
authors: S
authors: Ninomiya
authors: Takayuki
authors: T
authors: Nakanishi
authors: Tomohiro
authors: T
authors: Kato
authors: Tsuyoshi
authors: T
authors: Takami
authors: Hisataka
authors: H
authors: Moriwaki
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018572:Disease-Free Survival; D058582:Double-Balloon Enteroscopy; D005260:Female; D006801:Humans; D007580:Jejunal Neoplasms / Q000401:mortality* / Q000473:pathology* / Q000628:therapy; D008228:Lymphoma, Non-Hodgkin / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D011446:Prospective Studies; D015996:Survival Rate; D014057:Tomography, X-Ray Computed
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