title: Aminocatalyzed asymmetric Diels-Alder reaction of 2,4-dienals and rhodanine/hydantoin derivatives.
abstract: Aminocatalyzed asymmetric Diels-Alder reaction between 2,4-dienals and rhodanine/hydantoin derivatives via trienamine mechanism has been developed to synthesize various spirocyclic compounds with good yields (up to 98%) and excellent stereoselectivities (up to 99% ee and >19 : 1 dr).
authors: Engineering Research Centre of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China.
authors: Kailong
authors: K
authors: Zhu
authors: Huicai
authors: H
authors: Huang
authors: Wenbin
authors: W
authors: Wu
authors: Yuan
authors: Y
authors: Wei
authors: Jinxing
authors: J
authors: Ye
mesh_terms: D002384:Catalysis; D061565:Cycloaddition Reaction; D006827:Hydantoins / Q000737:chemistry*; D012236:Rhodanine / Q000737:chemistry*; D013141:Spiro Compounds / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D006827:Hydantoins; D013141:Spiro Compounds; D012236:Rhodanine