title: Effects of adenotonsillectomy on polysomnographic parameters in children with sickle cell disease.
abstract: Obstructive sleep apnea (OSA) in the pediatric sickle cell disease (SCD) population can promote nightly hemoglobin oxygen desaturation, which increases the risk of central nervous system insult and may impair cognitive function. Adenotonsillectomy can ameliorate OSA symptoms, but its effect in children with SCD has not been fully investigated. We reviewed the effects of adenotonsillectomy in thirteen children with SCD by comparison of pre and post-adenotonsillectomy polysomnography (PSG) parameters. Significant reduction in hemoglobin oxygen desaturation, decreased apnea-hypopnea index, and increased rapid eye movement sleep occurred after adenotonsillectomy. Adenotonsillectomy promotes improvement in sleep quality in children with SCD and PSG-confirmed OSA.
authors: Department of Pediatrics Otolaryngology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
authors: Paul
authors: P
authors: Finch
authors: Rose Mary
authors: RM
authors: Stocks
authors: Matthew P
authors: MP
authors: Smeltzer
authors: Amy
authors: A
authors: Kimble
authors: Robert
authors: R
authors: Schoumacher
authors: Jane S
authors: JS
authors: Hankins
mesh_terms: D000233:Adenoidectomy; D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D017286:Polysomnography; D020181:Sleep Apnea, Obstructive / Q000209:etiology* / Q000601:surgery*; D014068:Tonsillectomy