title: [Isoflavonoids from roots of Astragalus membranaceus var. mongholicus].
abstract: OBJECTIVE
  To study the isoflavonoid constituents of the roots of Astragalus membranaceus var. mongholicus.
  
  
  METHODS
  Such column chromatography methods as HPD-100 macroporous adsorption resin, silica gel, polyamide and Sephadex LH-20 gel were used for seperating and purifying isoflavonoids, and their structures were identified on the basis of spectral data.
  
  
  RESULTS
  Fourteen compounds were separated and identified as: formononetin (1), ononin (2) calycosin (3), calycosin-7-O-beta-3-D-glucopyranoside (4), (6aR, 11aR)-3-hydroxy-9,10-dimethoxypterocarpan (5), (6aR, 11aR)-3-hydroxy-9,10-dimethoxypterocarpan-3-O-beta-D-glucopyranoside (6), (3R) -7,2'-dihydroxy-3', 4'-dimethoxyisoflavan (7), (3R) -7, 2'-dihydroxy-3', 4'-dimethoxyisoflavan-7-O-beta-D-glucopyranoside (8), 6"-O-acetyl-ononin (9), 6"-O-acetyl-(3R) -7, 2'-dihydroxy-3', 4'-dimethoxyisoflavan-7-O-beta-D-glucopyranoside (10), 6"-O-acetyl-(6aR, 11aR)-3-hydroxy-9, 10-dimethoxypterocarpan-3-O-beta-D-glucopyranoside (11), pratensein (12), sissotrin (13) and 5,7,4'-trihydroxy-3'-methoxyisoflavone (14).
  
  
  CONCLUSIONS
  Compound 10 was a new compound. Compounds 9, 11, 13,14 were separated from A. membranaceus var. mongholicus for the first time.
authors: School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. yazhou_zhang2009@163.com
authors: Ya-Zhou
authors: YZ
authors: Zhang
authors: Feng
authors: F
authors: Xu
authors: Jing
authors: J
authors: Liang
authors: Jing-Shu
authors: JS
authors: Tang
authors: Ming-Ying
authors: MY
authors: Shang
authors: Xuan
authors: X
authors: Wang
authors: Shao-Qing
authors: SQ
authors: Cai
mesh_terms: D027885:Astragalus propinquus / Q000737:chemistry*; D007529:Isoflavones / Q000032:analysis* / Q000737:chemistry; D010936:Plant Extracts / Q000032:analysis; D018517:Plant Roots / Q000737:chemistry
chemical_list: D007529:Isoflavones; D010936:Plant Extracts