title: Draft genome sequence of the rubber tree Hevea brasiliensis.
abstract: BACKGROUND
  Hevea brasiliensis, a member of the Euphorbiaceae family, is the major commercial source of natural rubber (NR). NR is a latex polymer with high elasticity, flexibility, and resilience that has played a critical role in the world economy since 1876.
  
  
  RESULTS
  Here, we report the draft genome sequence of H. brasiliensis. The assembly spans ~1.1 Gb of the estimated 2.15 Gb haploid genome. Overall, ~78% of the genome was identified as repetitive DNA. Gene prediction shows 68,955 gene models, of which 12.7% are unique to Hevea. Most of the key genes associated with rubber biosynthesis, rubberwood formation, disease resistance, and allergenicity have been identified.
  
  
  CONCLUSIONS
  The knowledge gained from this genome sequence will aid in the future development of high-yielding clones to keep up with the ever increasing need for natural rubber.
authors: Centre for Chemical Biology, Universiti Sains Malaysia, Penang, Malaysia.
authors: Ahmad Yamin Abdul
authors: AY
authors: Rahman
authors: Abhilash O
authors: AO
authors: Usharraj
authors: Biswapriya B
authors: BB
authors: Misra
authors: Gincy P
authors: GP
authors: Thottathil
authors: Kandakumar
authors: K
authors: Jayasekaran
authors: Yun
authors: Y
authors: Feng
authors: Shaobin
authors: S
authors: Hou
authors: Su Yean
authors: SY
authors: Ong
authors: Fui Ling
authors: FL
authors: Ng
authors: Ling Sze
authors: LS
authors: Lee
authors: Hock Siew
authors: HS
authors: Tan
authors: Muhd Khairul Luqman Muhd
authors: MK
authors: Sakaff
authors: Beng Soon
authors: BS
authors: Teh
authors: Bee Feong
authors: BF
authors: Khoo
authors: Siti Suriawati
authors: SS
authors: Badai
authors: Nurohaida Ab
authors: NA
authors: Aziz
authors: Anton
authors: A
authors: Yuryev
authors: Bjarne
authors: B
authors: Knudsen
authors: Alexandre
authors: A
authors: Dionne-Laporte
authors: Nokuthula P
authors: NP
authors: Mchunu
authors: Qingyi
authors: Q
authors: Yu
authors: Brennick J
authors: BJ
authors: Langston
authors: Tracey Allen K
authors: TA
authors: Freitas
authors: Aaron G
authors: AG
authors: Young
authors: Rui
authors: R
authors: Chen
authors: Lei
authors: L
authors: Wang
authors: Nazalan
authors: N
authors: Najimudin
authors: Jennifer A
authors: JA
authors: Saito
authors: Maqsudul
authors: M
authors: Alam
mesh_terms: D000485:Allergens / Q000235:genetics; D060467:Disease Resistance / Q000235:genetics; D019143:Evolution, Molecular; D044783:F-Box Proteins / Q000235:genetics; D018745:Genome, Plant / Q000235:genetics; D023281:Genomics; D006238:Haploidy; D028482:Hevea / Q000235:genetics* / Q000276:immunology / Q000378:metabolism; D007840:Latex / Q000378:metabolism; D058977:Molecular Sequence Annotation; D010802:Phylogeny; D010937:Plant Growth Regulators / Q000235:genetics; D012408:Rubber / Q000378:metabolism; D017421:Sequence Analysis; D015398:Signal Transduction / Q000235:genetics; D014157:Transcription Factors / Q000235:genetics; D014934:Wood / Q000378:metabolism
chemical_list: D000485:Allergens; D044783:F-Box Proteins; D007840:Latex; D010937:Plant Growth Regulators; D014157:Transcription Factors; D012408:Rubber
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