title: [Takotsubo cardiomyopathy: a novel beta-adrenergic blocker withdrawal syndrome].
abstract: The authors describe two cases of takotsubo cardiomyopathy developing after an abrupt withdrawal of carvedilol and bisoprolol. Takotsubo or stress cardiomyopathy is characterized by acute and reversible cardiac dysfunction without coronary artery disease. It is triggered by acute emotional or physical stress, drugs or drug withdrawal. The immediate discontinuation of the long acting vasodilator beta-blocker, carvedilol has not yet been described to cause takotsubo cardiomyopathy. The authors recommend cautious withdrawal of beta-blockers.
authors: Budai Irgalmasrendi Kórház Kardiológia Budapest.
authors: János
authors: J
authors: Tomcsányi
authors: Kinga
authors: K
authors: Jávor
authors: Hrisula
authors: H
authors: Arabadzisz
authors: András
authors: A
authors: Zsoldos
authors: Vince
authors: V
authors: Wagner
authors: Balázs
authors: B
authors: Sármán
mesh_terms: D058671:Adrenergic beta-1 Receptor Antagonists / Q000008:administration & dosage / Q000009:adverse effects; D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage* / Q000009:adverse effects*; D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000188:drug therapy*; D017298:Bisoprolol / Q000008:administration & dosage / Q000009:adverse effects; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000187:drug effects* / Q000503:physiopathology; D006801:Humans; D013375:Substance Withdrawal Syndrome / Q000209:etiology* / Q000503:physiopathology; D054549:Takotsubo Cardiomyopathy / Q000139:chemically induced* / Q000503:physiopathology
chemical_list: D058671:Adrenergic beta-1 Receptor Antagonists; D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D017298:Bisoprolol