title: [Inspirations from natural products based drug research and development for Chinese medicine research--analysis of natural products recoded in TTD].
abstract: Natural product is an important source of new drug research and development (R&D). Traditional Chinese medicine (TCM) innovation is the key step for its modernization and internationalization. However, due to the complexity of TCM, there are many difficulties and confusions in this process. Target-based drug discovery is the mainstream model and method of R&D. TTD, short for therapeutic target database, is developed by National University of Singapore. Besides a large amount of information on drug targets, the database also contains considerable information related to natural products. This paper briefly introduces the TTD, analyzes the natural products derived drugs/compounds recorded in TTD, which we think might provide some inspiration for the innovation of TCM.
authors: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau 999078, China. xpchen@umac.mo
authors: Xiu-Ping
authors: XP
authors: Chen
authors: Jin-Jian
authors: JJ
authors: Lu
authors: Jia-Jie
authors: JJ
authors: Guo
authors: Jiao-Lin
authors: JL
authors: Bao
authors: Wen-Shan
authors: WS
authors: Xu
authors: Qian
authors: Q
authors: Ding
authors: Yi-Tao
authors: YT
authors: Wang
mesh_terms: D016208:Databases, Factual; D016503:Drug Delivery Systems; D055808:Drug Discovery; D004365:Drugs, Chinese Herbal; D008516:Medicine, Chinese Traditional; D012846:Singapore
chemical_list: D004365:Drugs, Chinese Herbal