title: Fulminant type 1 diabetes mellitus: a new class of type 1 diabetes.
abstract: Fulminant Type 1 diabetes is a novel subtype of Type 1 diabetes. In this disease, extremely rapid and almost complete beta-cell destruction occurs, resulting in nearly no residual insulin secretion even just after the onset. The number of patients presumably amounts to 5,000-7,000 in Japan. The involvement of both, genetic background and viral infection, has been suggested in the pathogenesis of this disease. Diagnostic criteria were established by a committee of the Japan Diabetes Society in 2004. Intensive insulin therapy is a standard therapy. We should pay special attention to early development of microvascular complications in fulminant Type 1 diabetes.
authors: Department of Internal Medicine (I), Osaka Medical College, Takatsuki, Osaka, Japan.
authors: Saeko
authors: S
authors: Shibasaki
authors: Akihisa
authors: A
authors: Imagawa
authors: Toshiaki
authors: T
authors: Hanafusa
mesh_terms: D000208:Acute Disease; D048909:Diabetes Complications / Q000145:classification / Q000188:drug therapy / Q000453:epidemiology; D003922:Diabetes Mellitus, Type 1 / Q000145:classification* / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D007328:Insulin / Q000627:therapeutic use; D007564:Japan / Q000453:epidemiology; D015995:Prevalence; D012720:Severity of Illness Index
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin