title: Prevalence of Osteoporosis and Its Associated Factors among Older Men with Type 2 Diabetes.
abstract: This study investigated the prevalence of osteoporosis and its associated factors in old men with T2DM to identify risk factors for low BMD. We enrolled 93 old men (≥60 years of age) with T2DM and 125 healthy old men (controls) and collected data of their lifestyle, medical history, bone densitometry, body weight, height, and blood pressure. Blood samples were collected for biochemical analyses. Urine samples were collected to determine 24 h urinary creatinine, albumin, and protein. Although no differences in age, blood pressure, waist-to-hip ratio, body mass index (BMI), and testosterone levels were observed, the prevalence of low BMD was significantly higher in the T2DM group compared to the control group. The risk of developing low BMD and fracture in T2DM subjects was increased by 46- and 26-fold, respectively, compared to control subjects. BMD of total spine and hip was positively correlated with BMI and negatively correlated with age, duration of diabetes, creatinine, and 24 h urinary albumin. So old men with T2DM have a greater risk of developing low BMD than old men without T2DM.
authors: Department of Endocrinology, Jishuitan Hospital, Beijing 100035, China.
authors: Hai-Ling
authors: HL
authors: Chen
authors: Li-Li
authors: LL
authors: Deng
authors: Ju-Fen
authors: JF
authors: Li
references: Ann Endocrinol (Paris). 2012 Dec;73(6):546-51
references: 23122575
references: World Health Organ Tech Rep Ser. 1994;843:1-129
references: 7941614
references: BMJ. 2000 Feb 5;320(7231):341-6
references: 10657327
references: Osteoporos Int. 2000;11 Suppl 6:S55-65
references: 11193240
references: Arch Intern Med. 2008 Jan 14;168(1):47-54
references: 18195195
references: Geriatrics. 2000 May;55(5):31-6; quiz 39
references: 10826263
references: Arch Med Res. 2007 Feb;38(2):259-64
references: 17227738
references: Braz J Med Biol Res. 2007 Feb;40(2):221-7
references: 17273658
references: Endocr J. 2011;58(8):613-24
references: 21778617
references: Calcif Tissue Int. 2008 Dec;83(6):365-7
references: 19009314
references: Curr Opin Endocrinol Diabetes Obes. 2012 Apr;19(2):128-35
references: 22262002
references: Rev Endocr Metab Disord. 2004 Aug;5(3):261-8
references: 15211098
references: J Bone Miner Metab. 2004;22(4):287-92
references: 15221485
references: Am J Physiol Endocrinol Metab. 2005 Nov;289(5):E735-45
references: 16215165
references: Diabetes Metab. 2008 Jun;34(3):193-205
references: 18308607
references: J Bone Miner Res. 1992 Jun;7(6):633-8
references: 1414481
references: Clin Calcium. 2007 Feb;17(2):186-91
references: 17272875
references: Diabetologia. 2006 May;49(5):863-71
references: 16518589
references: Ther Adv Musculoskelet Dis. 2011 Aug;3(4):191-200
references: 22870478
references: Aging Clin Exp Res. 2011 Apr;23(2):84-90
references: 21743287
references: J Bone Miner Res. 2008 Jan;23(1):143-50
references: 17907920
references: Osteoporos Int. 2001;12(10):811-22
references: 11716183
references: Osteoporos Int. 2006 Feb;17(2):297-303
references: 16175311
references: Ann Epidemiol. 2007 Jul;17(7):514-9
references: 17420142
references: Clin Calcium. 2008 Jul;18(7):904-11
references: 18591740
references: Endocr Pract. 2007 Oct;13(6):620-8
references: 17954418
references: J Bone Miner Res. 2007 Sep;22(9):1317-28
references: 17501667
references: Aging Clin Exp Res. 2008 Aug;20(4):280-9
references: 18852539
references: Diabetes Res Clin Pract. 1994 Feb;23(1):43-54
references: 8013262
references: J Bone Miner Res. 2008 Feb;23(2):205-14
references: 17937534
references: N Engl J Med. 2008 Apr 3;358(14):1474-82
references: 18385499
references: J Bone Miner Res. 2006 Feb;21(2):292-9
references: 16418785
references: Nat Med. 2012 Jul;18(7):1095-101
references: 22729283
references: Patient Prefer Adherence. 2012;6:435-48
references: 22791981
references: Osteoporos Int. 2005 Aug;16(8):907-13
references: 15558237
references: J Bone Miner Res. 2008 Aug;23(8):1334-42
references: 18348689
references: Nutrition. 2004 Sep;20(9):769-71
references: 15325685
references: J Diabetes Complications. 2009 Jan-Feb;23(1):12-7
references: 18413190
references: J Bone Miner Res. 2005 Mar;20(3):494-500
references: 15746995
references: J Bone Miner Res. 2007 Mar;22(3):465-75
references: 17144789
references: J Bone Miner Res. 2003 Feb;18(2):312-8
references: 12568408
references: J Clin Endocrinol Metab. 2006 Oct;91(10):3908-15
references: 16849417
references: Curr Med Res Opin. 2009 May;25(5):1057-72
references: 19292601
references: J Clin Densitom. 2007 Oct-Dec;10(4):386-90
references: 17993401
references: Osteoporos Int. 2007 Apr;18(4):427-44
references: 17068657
references: J Bone Miner Res. 2005 Apr;20(4):596-603
references: 15765178
references: Curr Diab Rep. 2003 Feb;3(1):37-42
references: 12643144
references: Gend Med. 2012 Jun;9(3):187-96
references: 22503604
references: Ann Nutr Metab. 2004;48(3):141-5
references: 15133318