title: The movement of actin-myosin biomolecular linear motor under AC electric fields: an experimental study.
abstract: The role of actin-myosin as a biomolecular linear motor is considered a transport system at nanoscale because of their size, efficiency and functionality. To utilize the ability to transport, it is essential to control the random movement of actin filaments (F-actin) on myosin coated substrate. In the presence of an alternating current (AC) electric field, the direction of F-actin movement is regulated by electro-orientation torque and, as a result, its movement is perpendicularly toward the electrode edges. Our data confirm such aligned movement is proportional to the strength of applied electric field. Interestingly, the aligned movement is found frequency-dependent and the electrothermal effect is observed by means of the velocity measurement of aligned F-actin movement. The findings in this study may provide constructive information for manipulating actin-myosin nanotransport system to build functional nanodevices in future work.
authors: Lane Department of Computer Science and Electrical Engineering, West Virginia University, Morgantown, WV 26506, USA.
authors: Yongkuk
authors: Y
authors: Lee
authors: Parviz
authors: P
authors: Famouri
mesh_terms: D008841:Actin Cytoskeleton / Q000378:metabolism* / Q000648:ultrastructure; D000199:Actins / Q000378:metabolism* / Q000648:ultrastructure; D000818:Animals; D004560:Electricity; D004867:Equipment Design; D008839:Microelectrodes; D008853:Microscopy / Q000295:instrumentation; D009068:Movement; D009218:Myosins / Q000378:metabolism* / Q000648:ultrastructure; D011817:Rabbits
chemical_list: D000199:Actins; D009218:Myosins