title: Obesity and its impact on transplantation and alloimmunity.
abstract: Obesity has become an increasing problem in healthcare worldwide with far-reaching consequences. More obese patients with irreversible end-stage organ failure undergo organ transplantation, and organs from obese donors are more frequently used. A growing body of evidence suggests more frequent postoperative complications and inferior patient and graft survival linked to obesity. More recently, adipose tissue has been linked to chronic inflammatory processes potentially impacting alloimmune responses and graft quality.
authors: Division of Transplant Surgery and Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
authors: Timm
authors: T
authors: Heinbokel
authors: Bernhard
authors: B
authors: Floerchinger
authors: Andreas
authors: A
authors: Schmiderer
authors: Karoline
authors: K
authors: Edtinger
authors: Guangxiang
authors: G
authors: Liu
authors: Abdallah
authors: A
authors: Elkhal
authors: Stefan G
authors: SG
authors: Tullius
mesh_terms: D006084:Graft Rejection / Q000453:epidemiology / Q000276:immunology*; D006085:Graft Survival / Q000276:immunology; D006801:Humans; D007518:Isoantibodies / Q000276:immunology*; D009765:Obesity / Q000453:epidemiology / Q000276:immunology*; D015995:Prevalence; D014180:Transplantation; D014181:Transplantation Immunology
chemical_list: D007518:Isoantibodies