title: Demineralized bone matrix in extraction sockets: a clinical and histologic case series.
abstract: OBJECTIVE
  To evaluate its efficacy and predictability in immediate extraction sockets, this case series used demineralized bone matrix in a puttylike carrier (DBM putty) with and without mineralized bone chips. Each preparation was made from the long bones of the same tissue donor; the only excipient material was water.
  
  
  METHODS
  A single failing tooth was atraumatically extracted from each study subject, and the socket was debrided. Intact sockets were grafted with DBM putty (n = 6), and sockets with buccal defects were grafted with DBM putty with bone chips (n = 6). A bovine pericardium membrane was draped over the graft site, and tension-free primary closure was obtained. After 6 months of healing, a trephine biopsy was taken from the center of each graft, and then, a dental implant was placed. Two subjects were withdrawn, and histologic data could not be obtained from 2 other patients.
  
  
  RESULTS
  Mean new bone fill was 40.28% for DBM putty (n = 5) and 44.60% for DBM putty with bone chips (n = 4).
  
  
  CONCLUSIONS
  Both preparations maintained ridge dimensions and, despite ongoing bone turnover, produced adequate mineralized tissue that enabled implant placement at 6 months. This finding warrants further research.
authors: Department of Periodontics and Implant Dentistry, New York University, New York, NY, USA. edgard@edgardelchaar.com
authors: Edgard S
authors: ES
authors: El-Chaar
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000540:Alveolar Ridge Augmentation / Q000379:methods; D000818:Animals; D001706:Biopsy; D018775:Bone Demineralization Technique; D015519:Bone Density / Q000502:physiology; D001857:Bone Matrix / Q000473:pathology / Q000637:transplantation*; D016025:Bone Transplantation / Q000379:methods; D002417:Cattle; D054893:Cone-Beam Computed Tomography / Q000379:methods; D003758:Dental Implantation, Endosseous / Q000379:methods; D015921:Dental Implants; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010011:Osteocytes / Q000473:pathology; D010012:Osteogenesis / Q000502:physiology; D010496:Pericardium / Q000637:transplantation; D059745:Piezosurgery / Q000379:methods; D014021:Tissue Preservation / Q000379:methods; D014081:Tooth Extraction; D020390:Tooth Socket / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants