title: Experimental hut evaluation of Fendona 6SC®-treated bednets and Interceptor®  long-lasting nets against Anopheles gambiae s.l. in Burkina Faso.
abstract: OBJECTIVE
  Malaria prevention relies heavily on insecticide-treated bednets. Even though the benefits of bednets have been proven that in most of the studies carried out in Africa, their efficacy remains dependent on local conditions. In this study, under field conditions, we evaluated the efficacy of two LLINs (PermaNet® vs Interceptor® ) and two bednet treatment kits (K-O TAB® vs Fendona 6SC® ) against Anopheles gambiae s.l.
  
  
  METHODS
  Bednets were evaluated using experimental huts in the village of Pissy located in the Saponé health district of Burkina Faso. Treatments and sleepers were randomly rotated between huts. Results are expressed in terms of induced exophily, mortality after 24 h and blood-feeding inhibition.
  
  
  RESULTS
  A total of 1392 An. gambiae s.l. mosquitoes were collected during 120 nights in the experimental huts. The overall mortality rates were 85.4% (CL: 79.7-91.4) and 77.5% (CL: 56.9-97.3) for PermaNet® and Interceptor® ,respectively. For the conventionally treated bednets, the mortality was 78.2% (CL: 63.13-96.7) with the Fendona 6SC®-treated nets and 75.5% (CL: 61.2-93) with the K-O TAB®-treated nets. The proportion of blood-fed mosquitoes was significantly higher in the untreated bednet arm than in the treated one, as well as for long-lasting nets than for conventionally treated nets. The entry rate did not vary significantly according to the bednet type, but the treated bednets increased the level of exophily by at least 43%.
  
  
  CONCLUSIONS
  In the field, the Fendona 6SC® kit and the Interceptor bednets showed comparable efficacy to the already used K-O TAB® kit and PermaNet® bednets. These results could help National Malaria Program managers to formulate appropriate policy for effective vector control.
authors: Centre National de Recherche et de Formation sur le Paludisme, Université de Ouagadougou, Groupe de Recherche Action en Santé, Ouagadougou, Burkina Faso. a.badolo@gmail.com
authors: Athanase
authors: A
authors: Badolo
authors: Wamdaogo M
authors: WM
authors: Guelbeogo
authors: Alfred B
authors: AB
authors: Tiono
authors: Abdoulaye
authors: A
authors: Traoré
authors: N'falé
authors: N
authors: Sagnon
authors: Sodiomon B
authors: SB
authors: Sirima
mesh_terms: D000818:Animals; D000852:Anopheles / Q000145:classification / Q000187:drug effects* / Q000502:physiology; D005260:Female; D006801:Humans; D057148:Insecticide-Treated Bednets / Q000469:parasitology*; D007306:Insecticides / Q000008:administration & dosage / Q000494:pharmacology*; D007846:Laundering / Q000379:methods; D018942:Macrolides / Q000008:administration & dosage / Q000494:pharmacology*; D008288:Malaria / Q000517:prevention & control; D009032:Mosquito Control / Q000379:methods*; D011722:Pyrethrins / Q000008:administration & dosage / Q000494:pharmacology*; D016896:Treatment Outcome
chemical_list: D007306:Insecticides; D018942:Macrolides; D011722:Pyrethrins; C078973:milbemycin oxime; C017160:cypermethrin