title: [Fluorescence property of a chemical probe for naked-eye and detection of Fe3+].
abstract: A higher selective and sensitive probe for the detection of Fe(III) in aqueous media was made using 2,4-Diisocyanatotoluene (TDI) as a bridge to couple Fe3 O4 nanoparticles(NPs) and Rhodamine-6G hydrazide. The characterization of composite materials with Infrared spectra(IR), Thermal Gravimetric analysis(TGA) and Transmission Emission Microscopy(TEM) points to the graft of Rhodamine-6G hydrazide onto the surface of the Fe3O4. The obvious color change of the probe solution from light grey to pink upon the addition of Fe3+ demonstrated the probe could be used for "naked-eye" detection of Fe3+ in water at pH 7. The presence of 1 equivalent (10 micromol x L(-1) microm) of each of these metal ions, including Mn2+, Ni2+, Y2+, Eu3+, Ce3+, La3+, Pr3+, Cd2+, Cr3+, Sm3+, Fe2+, Cu2+ and Zn2+ ions, did not demonstrate any obvious fluorescence change of the probe water solution, which confirmed the probe was a probe with remarkable selectivity for Fe3+. And the fluorescence images of HeLa cells in physiological solutions after incubation with Fe3+ and then further incubated with the probe leading to a strong intracellular fluorescence, which suggested the probe could penetrate the HeLa cell membrane and could respond to Fe3+ in intracellular within living cells.
authors: College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070, China. songym@nwnu.edu.cn
authors: Yu-Min
authors: YM
authors: Song
authors: Xin-Xian
authors: XX
authors: Ma
authors: Wu
authors: W
authors: Yang
mesh_terms: D002412:Cations / Q000032:analysis; D005290:Ferric Compounds / Q000032:analysis* / Q000737:chemistry; D052203:Ferrosoferric Oxide / Q000737:chemistry; D006367:HeLa Cells; D006801:Humans; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry; D061848:Optical Imaging; D012235:Rhodamines / Q000737:chemistry; D013055:Spectrophotometry, Infrared / Q000379:methods*; D014051:Toluene 2,4-Diisocyanate / Q000737:chemistry
chemical_list: D002412:Cations; D005290:Ferric Compounds; D058185:Magnetite Nanoparticles; D012235:Rhodamines; D014051:Toluene 2,4-Diisocyanate; D052203:Ferrosoferric Oxide