title: Diagnostic accuracy and use of nonmydriatic ocular fundus photography by emergency physicians: phase II of the FOTO-ED study.
abstract: OBJECTIVE
  During the first phase of the Fundus Photography vs Ophthalmoscopy Trial Outcomes in the Emergency Department study, 13% (44/350; 95% confidence interval [CI] 9% to 17%) of patients had an ocular fundus finding, such as papilledema, relevant to their emergency department (ED) management found by nonmydriatic ocular fundus photography reviewed by neuro-ophthalmologists. All of these findings were missed by emergency physicians, who examined only 14% of enrolled patients by direct ophthalmoscopy. In the present study, we evaluate the sensitivity of nonmydriatic ocular fundus photography, an alternative to direct ophthalmoscopy, for relevant findings when photographs are made available for use by emergency physicians during routine clinical care.
  
  
  METHODS
  Three hundred fifty-four patients presenting to our ED with headache, focal neurologic deficit, visual change, or diastolic blood pressure greater than or equal to 120 mm Hg had nonmydriatic fundus photography obtained (Kowa nonmydriatic α-D). Photographs were placed on the electronic medical record for emergency physician review. Identification of relevant findings on photographs by emergency physicians was compared with a reference standard of neuro-ophthalmologist review.
  
  
  RESULTS
  Emergency physicians reviewed photographs of 239 patients (68%). Thirty-five patients (10%; 95% CI 7% to 13%) had relevant findings identified by neuro-ophthalmologist review (6 disc edema, 6 grade III/IV hypertensive retinopathy, 7 isolated hemorrhages, 15 optic disc pallor, and 1 retinal vascular occlusion). Emergency physicians identified 16 of 35 relevant findings (sensitivity 46%; 95% CI 29% to 63%) and also identified 289 of 319 normal findings (specificity 91%; 95% CI 87% to 94%). Emergency physicians reported that photographs were helpful for 125 patients (35%).
  
  
  CONCLUSIONS
  Emergency physicians used nonmydriatic fundus photographs more frequently than they performed direct ophthalmoscopy, and their detection of relevant abnormalities improved. Ocular fundus photography often assisted ED care even when results were normal. Nonmydriatic ocular fundus photography offers a promising alternative to direct ophthalmoscopy.
authors: Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
authors: Beau B
authors: BB
authors: Bruce
authors: Praneetha
authors: P
authors: Thulasi
authors: Clare L
authors: CL
authors: Fraser
authors: Matthew T
authors: MT
authors: Keadey
authors: Antoinette
authors: A
authors: Ward
authors: Katherine L
authors: KL
authors: Heilpern
authors: David W
authors: DW
authors: Wright
authors: Nancy J
authors: NJ
authors: Newman
authors: Valérie
authors: V
authors: Biousse
mesh_terms: D000328:Adult; D015331:Cohort Studies; D057286:Electronic Health Records; D004635:Emergency Medicine / Q000379:methods*; D004636:Emergency Service, Hospital; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009184:Mydriatics; D009887:Ophthalmoscopy / Q000379:methods*; D010781:Photography / Q000379:methods*; D011446:Prospective Studies; D012164:Retinal Diseases / Q000175:diagnosis; D012680:Sensitivity and Specificity
chemical_list: D009184:Mydriatics