title: Two new triterpenoids from the fungus Perenniporia maackiae.
abstract: Two new triterpenoids, 3β-(2-methoxy-oxalyloxy)-24-methylene-lanost-8-en-21-oic acid (1) and 3β-(2-methoxy-oxalyloxy)-15α-hydroxy-24-methylene-lanost-8-en-21-oic acid (2), were isolated from cultures of the fungus Perenniporia maackiae, together with two previously known triterpenoids (3 and 4). Their structures were determined by spectroscopic methods, including 1D and 2D NMR, and MS analyses. All compounds were evaluated for their cytotoxic activities on five tumor cell lines.
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
authors: Hua
authors: H
authors: Guo
authors: Jing
authors: J
authors: Si
authors: Zheng-Hui
authors: ZH
authors: Li
authors: Tao
authors: T
authors: Feng
authors: Ze-Jun
authors: ZJ
authors: Dong
authors: Yu-Cheng
authors: YC
authors: Dai
authors: Ji-Kai
authors: JK
authors: Liu
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018922:HL-60 Cells; D006801:Humans; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011124:Polyporaceae / Q000737:chemistry*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: C582411:3beta(2-methoxy-oxalyloxy)-24-methylene-lanost-8-en-21-oic acid; C582410:3beta-(2-methoxy-oxalyloxy)-15alpha-hydroxy-24-methylene-lanost-8-en-21-oic acid; D000970:Antineoplastic Agents; D004365:Drugs, Chinese Herbal; D014315:Triterpenes