title: Quantification of visceral adipose tissue using lunar dual-energy X-ray absorptiometry in Asian Chinese.
abstract: OBJECTIVE
  To evaluate the new DXA VAT method on an Asian Chinese population by comparing to a reference method, computed tomography (CT).
  
  
  METHODS
  In total, 145 adult men and women volunteers, representing a wide range of ages (19-83 years) and BMI values (18.5-39.3 kg/m(2) ) were studied with both DXA and CT.
  
  
  RESULTS
  The coefficient of determination (r(2) ) for regression of CT on DXA values was 0.947 for females, 0.891 for males and 0.915 combined. The 95% confidence interval for r was 0.940-0.969 for the combined data. The Bland-Altman test showed a VAT bias (CT as standard method) of 143 cm(3) for females and 379 cm(3) for males. Combined, the bias was 262 cm(3) with 95% limits of agreement of -232 to 755 cm(3) . While the current DXA method moderately overestimates the VAT volume for the study subjects, a further analysis suggested that the overestimation could be largely contributed to VAT movement due to breath-holding status.
  
  
  CONCLUSIONS
  For Asian Chinese, VAT measured with DXA is highly correlated to VAT measured with CT. Validation of the DXA VAT tool using a reference method (e.g., CT) needs to carefully control the breath-holding protocol.
authors: Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University, Shanghai, China.
authors: Huandong
authors: H
authors: Lin
authors: Hongmei
authors: H
authors: Yan
authors: Shengxiang
authors: S
authors: Rao
authors: Mingfeng
authors: M
authors: Xia
authors: Qi
authors: Q
authors: Zhou
authors: Hao
authors: H
authors: Xu
authors: Megan P
authors: MP
authors: Rothney
authors: Yi
authors: Y
authors: Xia
authors: Wynn K
authors: WK
authors: Wacker
authors: David L
authors: DL
authors: Ergun
authors: Mengsu
authors: M
authors: Zeng
authors: Xin
authors: X
authors: Gao
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People / Q000208:ethnology*; D001823:Body Composition; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat / Q000033:anatomy & histology*; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000379:methods; D055105:Waist Circumference; D055815:Young Adult