title: DART MS based chemical profiling for therapeutic potential of Piper betle landraces.
abstract: Piper betle Linn. leaves are traditionally used as a folk medicine in India and other Asiatic countries. Twenty-one P. betle landraces were analyzed using a Direct Analysis in Real Time (DART) mass spectral technique and evaluated on the basis of molecules detected in the leaves. Clustering of landraces based on three well known biologically active phenols (m/z 151,165,193) showed two broad groups with high and low phenol contents suggesting differences in their therapeutic potential. Findings of this study could be useful in rapid screening of the landraces for determining their medicinal potential and optimum utilization of the bioresource.
authors: Sophisticated Analytical Instrument Facility, Central Drug Research Institute (CSIR), Lucknow-226001, India.
authors: Vikas
authors: V
authors: Bajpai
authors: Renu
authors: R
authors: Pandey
authors: Mahendra Pal Singh
authors: MP
authors: Negi
authors: Nikhil
authors: N
authors: Kumar
authors: Brijesh
authors: B
authors: Kumar
mesh_terms: D002138:Calibration; D003199:Computer Systems; D004353:Drug Evaluation, Preclinical; D013058:Mass Spectrometry; D009822:Oils, Volatile / Q000737:chemistry; D010636:Phenols / Q000737:chemistry / Q000627:therapeutic use; D031721:Piper betle / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D012984:Software
chemical_list: D009822:Oils, Volatile; D010636:Phenols