title: HCV infection among cocaine users in the state of Pará, Brazilian Amazon.
abstract: In this study, the prevalence, genotype frequency, and risk factors for HCV infection in 384 cocaine users were determined. One hundred twenty-four (32.3 %) cocaine users had anti-HCV antibodies and 120 (31.3 %) had HCV-RNA. Genotyping results indicated the predominance of genotypes 1 (73.3 %) and 3 (26.7 %). Multivariate analysis showed an association of HCV infection with tattoos, shared use of paraphernalia, daily cocaine use, and a long history of cocaine use. The epidemiological aspects of HCV infection among cocaine users presented here should serve as an incentive for the establishment of a program of hepatitis C prevention and control by the local public-health authorities in the Amazon.
authors: Faculdade de Ciências Naturais, Campus do Marajó, Breves, Universidade Federal do Pará, Av. Anajás, s/n. Aeroporto, Breves, PA, Brazil. olivfilho@ufpa.br
authors: Aldemir B
authors: AB
authors: Oliveira-Filho
authors: Leila
authors: L
authors: Sawada
authors: Laine C
authors: LC
authors: Pinto
authors: Daiane
authors: D
authors: Locks
authors: Santana L
authors: SL
authors: Bahia
authors: I
authors: I
authors: Brasil-Costa
authors: José Alexandre R
authors: JA
authors: Lemos
mesh_terms: D000293:Adolescent; D000328:Adult; D001938:Brazil; D003042:Cocaine; D003430:Cross-Sectional Studies; D055030:Drug Users; D005260:Female; D005838:Genotype; D016174:Hepacivirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D006526:Hepatitis C / Q000453:epidemiology* / Q000821:virology; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012367:RNA, Viral / Q000097:blood; D012307:Risk Factors; D055815:Young Adult
chemical_list: D018937:Hepatitis C Antibodies; D012367:RNA, Viral; D003042:Cocaine