title: A new development in DNA repair modulation: discovery of a BLM helicase inhibitor.
authors: Taraswi
authors: T
authors: Banerjee
authors: Monika
authors: M
authors: Aggarwal
authors: Robert M
authors: RM
authors: Brosh
mesh_terms: D004265:DNA Helicases / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism; D004260:DNA Repair / Q000187:drug effects*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D000067856:Poly(ADP-ribose) Polymerase Inhibitors; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism; D053484:RecQ Helicases / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism; D054852:Small Molecule Libraries / Q000494:pharmacology
chemical_list: D004791:Enzyme Inhibitors; D000067856:Poly(ADP-ribose) Polymerase Inhibitors; D054852:Small Molecule Libraries; D011065:Poly(ADP-ribose) Polymerases; C097151:Bloom syndrome protein; D004265:DNA Helicases; D053484:RecQ Helicases
keywords: Bloom's syndrome; DNA repair; RecQ; anticancer therapy; helicase; high-throughput screening; inhibitor; molecular probes; small molecules; synthetic lethality