title: Training increases anabolic response and reduces inflammatory response to a single practice in elite male adolescent volleyball players.
abstract: We examined the effect of training on hormonal and inflammatory response to a single volleyball practice in elite adolescent players. Fourteen male, elite, national team-level, Israeli volleyball players (age, 16.3±1.1 years, Tanner stage 4-5) participated in the study. Blood samples were collected before and immediately after a typical 60-min volleyball practice, before and after 7 weeks of training during the initial phases of the volleyball season. Hormonal measurements included the anabolic hormones growth hormone (GH), insulin-like growth factor 1 (IGF-1), IGF-binding protein 3, and testosterone; the catabolic hormone cortisol; the pro-inflammatory markers interleukin (IL) 6, and the anti-inflammatory marker IL-1 receptor antagonist. Training led to a significant improvement of both anaerobic and aerobic properties. Before the training intervention, the typical volleyball practice was associated with a significant increase of GH and testosterone and also with a significant increase of IL-6. Training resulted in a significantly greater GH response (ΔGH, 2.5±2.4 vs. 4.7±3.0 ng/mL, before and after training, respectively; p<0.02) and reduced IL-6 response (ΔIL-6, 2.0±1.6 vs. 0.6±0.7 pg/mL, before and after training, respectively; p<0.01) to the same relative intensity volleyball practice. The results suggest that, along with the improvement of anaerobic and aerobic characteristics, training leads to a greater anabolic and reduced inflammatory response to exercise.
authors: Pediatric Department, Meir Medical Center, Tel Aviv University, Tel Aviv, Israel. dnemet@gmail.com
authors: Dan
authors: D
authors: Nemet
authors: Shawn
authors: S
authors: Portal
authors: Zvi
authors: Z
authors: Zadik
authors: Rutie
authors: R
authors: Pilz-Burstein
authors: Dana
authors: D
authors: Adler-Portal
authors: Yoav
authors: Y
authors: Meckel
authors: Alon
authors: A
authors: Eliakim
mesh_terms: D000293:Adolescent; D015444:Exercise; D019382:Human Growth Hormone / Q000097:blood; D006801:Humans; D007249:Inflammation / Q000517:prevention & control*; D018972:Insulin-Like Growth Factor Binding Protein 3 / Q000097:blood; D007334:Insulin-Like Growth Factor I; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D013739:Testosterone / Q000097:blood; D054798:Volleyball
chemical_list: D018972:Insulin-Like Growth Factor Binding Protein 3; D015850:Interleukin-6; D019382:Human Growth Hormone; D013739:Testosterone; D007334:Insulin-Like Growth Factor I