title: Hepatic and splenic uptake on bone scintigraphy in patients with intravenous administration of 99mTc methylene diphosphonate prior to gadolinium-containing contrast.
abstract: Earlier studies indicate that abnormal liver and spleen uptake on bone scan has been observed in association with intravenous injection of Gd-DTPA contrast for MRI. All of these patients, however, received Gd-DTPA injection prior to (99m)Tc MDP administration. We report herein 3 patients with hepatic and splenic uptake on bone scan; all were administered (99m)Tc MDP before Gd-DTPA. Thus, we can conclude that Gd-DTPA after (99m)Tc MDP administration may also induce increased hepatic and splenic radioactivity on bone scan.
authors: Department of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu, China.
authors: Wenjie
authors: W
authors: Zhang
authors: Biling
authors: B
authors: Chen
authors: Houfu
authors: H
authors: Deng
authors: Tianxia
authors: T
authors: Yang
authors: Xiaohong
authors: X
authors: Ou
mesh_terms: D061605:Administration, Intravenous; D000368:Aged; D001692:Biological Transport; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D003287:Contrast Media; D005682:Gadolinium; D006801:Humans; D008099:Liver / Q000378:metabolism*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013154:Spleen / Q000378:metabolism*; D013669:Technetium Tc 99m Medronate / Q000008:administration & dosage* / Q000378:metabolism*
chemical_list: D003287:Contrast Media; D005682:Gadolinium; D013669:Technetium Tc 99m Medronate