title: New alkaloid from Streptomyces koyangensis residing in Odontotermes formosanus.
abstract: A new alkaloid was isolated from the ethyl acetate extract of the culture of a termite-associated Streptomyces koyangensis BY-4. The structure of 1 was elucidated by using MS, NMR, electronic circular dichroism data, and computational approaches. Compound 1 showed weak antimicrobial activities against a panel of test microbes.
authors: Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, China.
authors: Shu-Feng
authors: SF
authors: Bi
authors: Zhi-Kai
authors: ZK
authors: Guo
authors: Nan
authors: N
authors: Jiang
authors: Rui-Hua
authors: RH
authors: Jiao
authors: Hui-Ming
authors: HM
authors: Ge
authors: Ren-Xiang
authors: RX
authors: Tan
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000818:Animals; D001234:Aspergillus niger / Q000187:drug effects; D001412:Bacillus subtilis / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D002942:Circular Dichroism; D003455:Cryptococcus neoformans / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D007212:Indolizines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020049:Isoptera / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D016982:Micrococcus luteus / Q000187:drug effects; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects; D013297:Streptococcus pyogenes / Q000187:drug effects; D013302:Streptomyces / Q000737:chemistry*
chemical_list: C582359:2-ethyl-7-hydroxy-6,7-dihydro-5H-indolizin-3-one; D000470:Alkaloids; D007212:Indolizines