title: Resin infiltration of developmentally hypomineralised enamel.
abstract: BACKGROUND
  Molar incisor hypomineralisation (MIH) is a problematic condition with several characteristics for which infiltrant resins could theoretically improve clinical outcomes.
  
  
  OBJECTIVE
  To investigate whether caries infiltrant resin can penetrate MIH-affected enamel.
  
  
  METHODS
  Molar incisor hypomineralisation lesions (n = 21) were infiltrated using either the standard protocol or with the addition of a sodium hypochlorite (NaOCl) irrigation step. Lesions were sectioned and examined microscopically for infiltrant penetration before undergoing Vickers hardness testing. The surfaces of several lesions were also examined using scanning electron microscopy (SEM).
  
  
  RESULTS
  Infiltrant resin could penetrate MIH lesions; however, the pattern was erratic. Two lesions were confined to inner enamel, and no infiltration occurred. On average, the resin penetrated to a depth of 0.67 ± 0.39 mm and 23.1 ± 15.2% of the area of the lesion. Microhardness increased in areas of resin penetration by 1.0 ± 0.7 GPa representing a proportional increase of 2.2 ± 2.5 times. There were no significant differences in results based on either the infiltration protocol or the type of MIH lesion.
  
  
  CONCLUSIONS
  Caries infiltrant resin is capable of penetrating MIH enamel lesions; however, the pattern, extent, and change in hardness produced are currently unpredictable.
authors: Cooperative Research Centre for Oral Health Science, School of Dental Science, University of Melbourne, Melbourne, Vic., Australia.
authors: Felicity
authors: F
authors: Crombie
authors: David
authors: D
authors: Manton
authors: Joseph
authors: J
authors: Palamara
authors: Eric
authors: E
authors: Reynolds
mesh_terms: D003744:Dental Enamel Hypoplasia / Q000473:pathology*; D006244:Hardness; D006801:Humans; D066298:In Vitro Techniques; D008855:Microscopy, Electron, Scanning; D012117:Resins, Synthetic / Q000737:chemistry*; D013499:Surface Properties; D007507:Therapeutic Irrigation; D014094:Tooth, Deciduous
chemical_list: D012117:Resins, Synthetic; C578177:icon infiltrant