title: Treatment of osteoporotic vertebral compressive fractures with percutaneous kyphoplasty and oral Zishengukang.
abstract: OBJECTIVE
  To observe the therapeutic effect of percutaneous kyphoplasty (PKP) and oral Zishengukang (ZSGK) for the treatment of osteoporotic vertebral compression fractures (OVCFs).
  
  
  METHODS
  Seventy patients were randomly divided into a control group (PKP group) and an experimental group (PKP plus ZSGK group). The 35 patients in the experimental group were prescribed 6 g oral ZSGK three times a day for 90 days after PKP. Visual analog pain scale (VAS), Oswestry functional score, vertebral height and Cobb's angle were recorded and compared before treatment and at one week, one month and three months after treatment.
  
  
  RESULTS
  Vertebral height and Cobb's angle significantly improved and VAS and Oswestry functional score were significantly lower in both groups after PKP than pre-operatively (P < 0.01). Three months after treatment, VAS and Oswestry functional score in the experimental group were lower than controls (P < 0.05), even though vertebral height and Cobb's angle were comparable (P > 0.05).
  
  
  CONCLUSIONS
  PKP combined with oral ZSGK provide superior short-term and long-term symptom control after OVCF than PKP alone.
authors: Rehabilitation Centre, 309th Hospital of the People's Liberation Army of China, Beijing 100091, China. mhuangzhenjun521@126.com
authors: Zhenjun
authors: Z
authors: Huang
authors: Lijian
authors: L
authors: Zhang
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000627:therapeutic use*; D005260:Female; D050815:Fractures, Compression / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D058498:Kyphoplasty; D008297:Male; D008875:Middle Aged; D058866:Osteoporotic Fractures / Q000601:surgery* / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D004365:Drugs, Chinese Herbal