title: The quality of life of hematological malignancy patients with major depressive disorder or subsyndromal depression.
abstract: OBJECTIVE
  The purpose of the present study was to compare the quality of life of hematological malignancy patients with major depressive disorder or subsyndromal depression.
  
  
  METHODS
  Sample consisted of 93 hematological malignancy patients recruited from oncology ward of Valieasr hospital for Imam Khomeini complex hospital at Tehran through purposeful sampling. Participants were divided into three groups through diagnostic interview based on DSM-IV-TR criteria and the Beck Depression Inventory-2 (BDI-II): Major depressive disorder (MDD) (n = 41; 44.1%); subsyndromal depression (SSD) (n = 23; 24.7%), and without depression (WD) (n = 29; 31.2%). Participants completed the short-form health survey (SF-36) as a measure of the quality of life. We carried out an analysis of covariance to examine the collected data.
  
  
  RESULTS
  Findings showed that there was not a significant difference between patients with MDD and SSD based on measure of quality of life. But patients with MDD and SSD showed significantly worse quality of life than patients with WD. This finding highlights the clinical importance of subsyndromal depressive symptoms and casts doubt on the clinical utility of separation between MDD and subsyndromal depression in terms of important clinical outcomes.
authors: Department of Psychiatry, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. dr.rezaei@uswr.ac.ir
authors: Omid
authors: O
authors: Rezaei
authors: Ramezan-Ali
authors: RA
authors: Sharifian
authors: Mehdi
authors: M
authors: Soleimani
authors: Amirabbas
authors: A
authors: Jahanian
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003863:Depression / Q000150:complications / Q000523:psychology*; D003866:Depressive Disorder / Q000150:complications / Q000523:psychology*; D005260:Female; D006306:Health Surveys; D006801:Humans; D007938:Leukemia / Q000150:complications / Q000523:psychology*; D008223:Lymphoma / Q000150:complications / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology*