title: Angiofibromas with multiple epidermoid cysts in tuberous sclerosis: new mutation or post-traumatic?
abstract: Tuberous sclerosis is a genetic multisystem disorder characterized by widespread hamartomas in several organs. Clinically, more than 90% of affected patients have skin lesions including facial angiofibromas, periungual fibromas, hypomelanotic macule, etc. Periungual fibroma is one of the major diagnostic criteria of tuberous sclerosis and has the same pathology (angiofibroma) as the facial papules. We herein describe an interesting histologic variant of angiofibromas coupled with multiple epidermoid cysts in a 33-year-old patient with tuberous sclerosis.
authors: Department of Dermatology, The 251st Hospital of Chinese PLA, Zhangjiakou, China.
authors: Li-qiang
authors: LQ
authors: Zheng
authors: Yong
authors: Y
authors: Huang
authors: Xiang-chun
authors: XC
authors: Han
mesh_terms: D000328:Adult; D018322:Angiofibroma / Q000235:genetics* / Q000473:pathology; D004814:Epidermal Cyst / Q000235:genetics* / Q000473:pathology; D006222:Hamartoma / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male; D009154:Mutation; D009262:Nails / Q000473:pathology; D012878:Skin Neoplasms / Q000235:genetics* / Q000473:pathology; D014402:Tuberous Sclerosis / Q000235:genetics* / Q000473:pathology