title: [Diagnostic yield of pancreatic percutaneous puncture depending on the size of the lesion].
abstract: BACKGROUND
  The aim of the present study was to study the diagnostic efficacy of the percutaneous puncture of pancreatic tissue.
  
  
  METHODS
  A retrospective study was conducted on patients with suspicion of pancreatic neoplasm, and with a percutaneous biopsy of pancreatic tissue, from 2000 to 2011. For the statistical comparative analysis, the sample was stratified by tumour size: ≤ 3cm and > 3cm.
  
  
  RESULTS
  A total of 90 biopsies were performed. Pancreatic neoplasm diagnosis was made in 47 cases (52%), with 16 false negatives (18%), no false positives, and chronic pancreatitis in 24 cases (27%). The efficacy of the test results were: an overall sensitivity of 75% (95% CI: 62%-85%), a specificity of 100% (95% CI: 87%-100%), a positive predictive value of 100% (95% CI: 92%-100%), and a negative predictive value of 63% (95% CI: 46%-77%). For tumour sizes ≤ 3cm the sensitivity was 70% (95% CI: 45%-88%), with a specificity of 100% (95% CI 66%-100%), a positive predictive value of 100% (95% CI: 76%-100%, and a negative predictive value 60% (95% CI: 32%-83%). For tumours greater than 3cm, the sensitivity was 88% (95% CI: 70%-98%), the specificity was 100% (95% CI: 75%-100%), with a positive predictive value of 100% (95% CI: 85%-100%) and a negative predictive value of 81% (95% CI: 54%-96%).
  
  
  CONCLUSIONS
  Pancreatic percutaneous biopsy efficacy was strongly determined by lesion size. For tumour sizes less than 3cm, the sensitivity and negative predictive value are unacceptably low, as negative results would not reliable.
authors: Servicio de Cirugía General y Digestiva, Hospital General, Castellón, España. carlosfortea@gmail.com
authors: Carlos
authors: C
authors: Fortea-Sanchis
authors: Luis
authors: L
authors: Gómez-Quiles
authors: David
authors: D
authors: Martínez-Ramos
authors: Javier
authors: J
authors: Escrig Sos
authors: Gabriel Alejandro
authors: GA
authors: Paiva-Coronel
authors: Raquel
authors: R
authors: Queralt-Martín
authors: Álvaro
authors: Á
authors: Villarín-Rodríguez
authors: Laura
authors: L
authors: Granel-Villach
authors: José Luis
authors: JL
authors: Salvador-Sanchis
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000601:surgery; D011237:Predictive Value of Tests; D011677:Punctures / Q000379:methods; D012189:Retrospective Studies; D012680:Sensitivity and Specificity