title: Paraneoplastic cerebellar degeneration associated with ovarian cancer.
abstract: Paraneoplastic cerebellar degeneration (PCD) is a rare neurological disorder characterized by a widespread loss of Purkinje cells associated with a progressive pancerebellar dysfunction. PCD often precedes the cancer diagnosis by months to years. Here, we report the case of a 64-year-old woman who developed PCD symptoms, associated with high levels of anti-Yo antibodies, one year after a previous diagnosis of ovarian cancer. Clinical features, pathogenesis and treatment of PCD associated with cancer are discussed according to previous studies.
authors: Department of Biomedical Sciences, Section of Pathology and Oncology, Laboratory of Translational Oncology and Functional Genomics, University of Catania, Catania 95124; ; Department of Medical Oncology C, National Cancer Institute, IRCCS, Aviano 33081;
authors: Alessia Erika
authors: AE
authors: Russo
authors: Simona
authors: S
authors: Scalone
authors: Giulia Costanza
authors: GC
authors: Leonardi
authors: Aurora
authors: A
authors: Scalisi
authors: Giorgio
authors: G
authors: Giorda
authors: Roberto
authors: R
authors: Sorio
keywords: anti-Yo; ovarian cancer; paraneoplastic cerebellar degeneration