title: Comparative study of membranotropic action of single- and multi-walled carbon nanotubes.
abstract: The aim of the present work is the investigation of the interactions of single-walled and multi-walled carbon nanotubes (further referred as SWCNTs and MWCNTs, respectively) with bimolecular lipid model membrane (BLM) and cellular plasma membrane (PM). The findings demonstrate that both SWCNTs and MWCNTs (in concentration range of 10⁻⁴ to 10⁻¹ mg ml⁻¹) are capable to penetrate through the region of hydrophobic fatty acid residues of phospholipids and to form molecular associates in the bilayer that have conductive properties of molecular pores type. The formed pores were shown to enable phosphatidylserine externalization from inner to outer PM leaflet. Both types of CNTs increase the specific conductivity and decrease the specific capacity of BLM.
authors: Taras Shevchenko National University of Kyiv, Volodymyrska Str. 64, 01601 Kyiv, Ukraine.
authors: Svitlana
authors: S
authors: Prylutska
authors: Rostyslav
authors: R
authors: Bilyy
authors: Tatiana
authors: T
authors: Shkandina
authors: Daria
authors: D
authors: Rotko
authors: Andriy
authors: A
authors: Bychko
authors: Vsevolod
authors: V
authors: Cherepanov
authors: Rostyslav
authors: R
authors: Stoika
authors: Volodymyr
authors: V
authors: Rybalchenko
authors: Yuriy
authors: Y
authors: Prylutskyy
authors: Nikos
authors: N
authors: Tsierkezos
authors: Uwe
authors: U
authors: Ritter
mesh_terms: D002462:Cell Membrane / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D008563:Membrane Lipids / Q000737:chemistry*; D037742:Nanotubes, Carbon / Q000737:chemistry* / Q000648:ultrastructure; D010718:Phosphatidylserines / Q000032:analysis
chemical_list: D008563:Membrane Lipids; D037742:Nanotubes, Carbon; D010718:Phosphatidylserines