title: Two novel phenethylamine alkaloids from streptomyces sp. YIM10049.
abstract: Two novel phenethylamine alkaloids were isolated from Streptomyces sp. YIM 10049. On the basis of spectral data, their structures were determined as (S)-N-(cu-phenylethyl)-2 -hydroxyl-acrylimine (1) and (S)-N-nitroso-1-amino-p-hydroxy phenylethanol (2). Three known compounds, indole-3-carboxylic acid (3), cyclo(L-Ala-L-Tyr)(4), and bis(2-ethylhexyl) phthalate (5), were also isolated and characterized. Compound 1 is a rare enol tautomer, and compound 2 an unusual phenethylamine alkaloid with a N-NO group.
authors: Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
authors: Xueqiong
authors: X
authors: Yang
authors: Guangwei
authors: G
authors: He
authors: Lixing
authors: L
authors: Zhao
authors: Yabin
authors: Y
authors: Yang
authors: Yun
authors: Y
authors: Liu
authors: Lihua
authors: L
authors: Xu
authors: Zhongtao
authors: Z
authors: Ding
mesh_terms: D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000494:pharmacology; D045744:Cell Line, Tumor; D002855:Chromatography, Thin Layer; D005021:Ethylamines / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D005285:Fermentation; D005670:Fusarium / Q000187:drug effects; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D010627:Phenethylamines / Q000737:chemistry* / Q000302:isolation & purification; D013302:Streptomyces / Q000737:chemistry* / Q000254:growth & development
chemical_list: C578740:(S)-N-nitroso-1-amino-p-hydroxy phenylethanol; D000470:Alkaloids; D000903:Antibiotics, Antineoplastic; D000935:Antifungal Agents; D005021:Ethylamines; D010627:Phenethylamines