title: Comparison of follicle-stimulating hormone, estradiol, ovarian volume, and antral follicle count, based on the Stages of Reproductive Aging Workshop system, among community-based women in China.
abstract: OBJECTIVE
  This study aims to describe changes in follicle-stimulating hormone (FSH), estradiol (E2), ovarian volume (OV), and antral follicle count (AFC), and to examine their relationships at the same menopause stage, based on the Stages of Reproductive Aging Workshop (STRAW) system, among Chinese women in community settings.
  
  
  METHODS
  Prospective longitudinal study design was used to analyze the sex hormone levels, OV, and AFC of 327 community women aged 30 to 65 years. They were followed up at 1 year.
  
  
  RESULTS
  Significant differences in FSH, E2, and OV were observed at baseline and on follow-up (all P<0.001). Significant differences in E2 were observed between baseline and follow-up for women in premenopause (-2.743, P=0.006) and late postmenopause (-5.213, P<0.001). There were significant differences in FSH between baseline and follow-up in early menopausal transition (MT) (-2.430, P=0.015) and late MT (-3.737, P<0.001). There were significant differences in OV between baseline and follow-up in late MT (-3.805, P<0.001) and early postmenopause (-4.341, P<0.001). There were significant differences in AFC between baseline and follow-up in premenopause (-2.046, P=0.041).
  
  
  CONCLUSIONS
  These results suggest the existence of significant associations between FSH, E2, OV, AFC, and menopause status, supporting the use of the STRAW system among community-based women in China. Further study of the MT is recommended to confirm the appropriateness of the STRAW system for Chinese women.
authors: Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, PR China.
authors: Ning
authors: N
authors: Sun
authors: Shou-Qing
authors: SQ
authors: Lin
authors: Hui-Jun
authors: HJ
authors: Lin
authors: Zhong
authors: Z
authors: He
authors: Yan-Hong
authors: YH
authors: Wang
authors: Ying
authors: Y
authors: Zhang
authors: Feng-Ling
authors: FL
authors: Chen
authors: Ying
authors: Y
authors: Jiang
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging; D002681:China; D004958:Estradiol / Q000097:blood*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D008137:Longitudinal Studies; D008593:Menopause; D008875:Middle Aged; D006080:Ovarian Follicle / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D010053:Ovary / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D011446:Prospective Studies; D012098:Reproduction; D014463:Ultrasonography
chemical_list: D004958:Estradiol; D005640:Follicle Stimulating Hormone