title: Microbiologic isolates and risk factors associated with antimicrobial resistance in patients admitted to the intensive care unit in a tertiary care hospital.
abstract: This study reviewed the clinical and microbiologic data for patients admitted to the intensive care unit with hospital-acquired infections. In the multivariate analysis, AIDS and previous antibiotic use were associated with the emergence of multiresistant bacteria. Hematologic diseases, length of stay, number of days on central venous catheter, antimicrobial use, and presence of multiresistant bacteria were associated with death. The previous use of antibiotics and the length of the hospital stay contribute to the development of infections caused by multiresistant gram-negative bacteria.
authors: Infectious Diseases Section, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
authors: Juliana
authors: J
authors: da Silva Winter
authors: Rodrigo Pires
authors: RP
authors: Dos Santos
authors: Aline Z
authors: AZ
authors: de Azambuja
authors: Angélica Bauer
authors: AB
authors: Cechinel
authors: Luciano Zubaran
authors: LZ
authors: Goldani
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D001424:Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology* / Q000401:mortality; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology* / Q000401:mortality; D024881:Drug Resistance, Bacterial; D004363:Drug Utilization; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D062606:Tertiary Care Centers
chemical_list: D000900:Anti-Bacterial Agents
keywords: Bacterial resistance; Nosocomial infection; Patient outcome