title: One-pot three-component synthesis of pyrano [3,2-b]pyrazolo[4,3-e]pyridin-8(1H)-ones.
abstract: An efficient one-pot synthesis of novel pyrano[3,2-b]pyrazolo[4,3-e]pyridin-8(1H)-ones via three-component condensation of kojic acid, 1-H-pyrazol-5-amines and aldehydes in the presence of a catalytic amount of Zn(OTf)(2) followed by H(2)O(2)-mediated oxidation is reported. Furthermore, the synthesis of 1'H-spiro[indoline-3,4'-pyrano[2,3-b]pyrazolo[3,4-e]pyridine]-2,8'(9'H)-diones were chosen for the library validation.
authors: Catalysis Division, Department of Chemistry, University of Isfahan, Isfahan 81746-73441, Iran.
authors: Shirin
authors: S
authors: Safaei
authors: Iraj
authors: I
authors: Mohammadpoor-Baltork
authors: Ahmad Reza
authors: AR
authors: Khosropour
authors: Majid
authors: M
authors: Moghadam
authors: Shahram
authors: S
authors: Tangestaninejad
authors: Valiollah
authors: V
authors: Mirkhani
authors: Hamid Reza
authors: HR
authors: Khavasi
mesh_terms: D000447:Aldehydes / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D018360:Crystallography, X-Ray; D008958:Models, Molecular; D015394:Molecular Structure; D011720:Pyrazoles / Q000737:chemistry*; D047069:Pyrazolones / Q000138:chemical synthesis* / Q000737:chemistry; D011728:Pyridones / Q000138:chemical synthesis* / Q000737:chemistry; D011753:Pyrones / Q000737:chemistry*
chemical_list: C542126:1H-pyrazol-5-amine; D000447:Aldehydes; D011720:Pyrazoles; D047069:Pyrazolones; D011728:Pyridones; D011753:Pyrones; C585637:pyrano (3,2-b)pyrazolo(4,3-e)pyridin-8(1H)-one; C011890:kojic acid