title: Scytalidium and scytalidiosis: what's new in 2012?
abstract: Fungi belonging to the genus Scytalidium are widespread around the world. Among them, two species are responsible for human superficial infections mimicking dermatophytosis: Neoscytalidium dimidiatum and Scytalidium hyalinum. Whereas these ascomycetous fungi are endemic in tropical or subtropical countries, both species have a different geographical distribution. Scytalidiosis represents approximately 40% of dermatomycoses in these areas. A few cases of invasive infections due to Scytalidium sp. have also been reported, assessing the ability of these fungi to behave as opportunists. Here we have reviewed the data on N. dimidiatum and S. hyalinum concerning their classification, clinical features, diagnosis and treatment. We also have presented the example of a specific consultation dedicated to nails in Martinique, in order to optimize the diagnosis and treatment of onychomycosis, many of which being due to Scytalidium sp. Even if Scytalidium cases are still rare in temperate countries, imported cases may increase in the future due to immigration and travel.
authors: Service de Parasitologie-Mycologie, CHU de Brabois, 11 allée du Morvan, 54500 Vandoeuvre-les-Nancy, France. m.machouart@chu-nancy.fr
authors: M
authors: M
authors: Machouart
authors: P
authors: P
authors: Menir
authors: R
authors: R
authors: Helenon
authors: D
authors: D
authors: Quist
authors: N
authors: N
authors: Desbois
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003881:Dermatomycoses / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000628:therapy; D026141:Drug Resistance, Multiple, Fungal; D004641:Emigration and Immigration; D019353:Endemic Diseases; D016469:Fungemia / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology; D006801:Humans; D008395:Martinique / Q000453:epidemiology; D009181:Mycoses / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology* / Q000628:therapy; D014009:Onychomycosis / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology / Q000628:therapy; D009894:Opportunistic Infections / Q000453:epidemiology / Q000382:microbiology / Q000628:therapy; D010044:Outpatient Clinics, Hospital; D010348:Patient Care Team; D004718:Saccharomycetales / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity / Q000502:physiology; D013045:Species Specificity; D014195:Travel; D014329:Tropical Climate
chemical_list: D000935:Antifungal Agents