title: Post-transfusion increment of platelet count in thrombocytopenic patients treated with platelet concentrates.
abstract: The Platelet (PLT) Transfusion Therapy plays an important role in the support of surgical, haematological, oncological and transplant patients. The present study was assigned to find out the post transfusion increment of platelet count among the thrombocytopenic patients in Bangladeshi population. This descriptive study was conducted at the Departments of Haematology and Transfusion Medicine, BSMMU, Dhaka. Total 42 thrmbocytopenic patients were randomly assigned to receive a transfusion when their platelet counts below 10000 per cubic millimeter or with active bleeding. Pre transfusion and post transfusion platelet count were measured in all patients. Out of 42 patients, 26(61.90%) were male and 16(38.10%) were female. Leukemia was the most common cause of thrombocytopenia (47.62%). Most of the patients (71.34%) required transfusion of multiple units of platelet and 12(28.57%) patients required double units. Before transfusion of platelet concentrate <30×10⁸/L, 30-80×10⁸/L and >80×10⁸/L platelet count were found in 30(71.43%), 08(19.05%) and 04(09.52%) patients respectively. After transfusion of platelet concentrate <50×10⁸/L, 50-100×10⁸/L and >100×10⁸/L platelet count were found in 30(71.43%), 08(19.05%) and 04(09.52%) patients respectively. In all patients post transfusion platelet count increases but 2 or multiple units of transfusion were needed.
authors: Department of Transfusion Medicine, Dhaka Medical College, Dhaka, Bangladesh. dr_tapan2010@ yahoo.com
authors: M M
authors: MM
authors: Hoque
authors: M
authors: M
authors: Rahman
authors: S M
authors: SM
authors: Rahman
authors: M M
authors: MM
authors: Habibullah
authors: M A
authors: MA
authors: Faruki
authors: K H
authors: KH
authors: Rahman
authors: A A
authors: AA
authors: Mamun
authors: M A
authors: MA
authors: Hossain
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects; D001459:Bangladesh; D003715:Dengue / Q000150:complications; D005260:Female; D006470:Hemorrhage / Q000097:blood / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007938:Leukemia / Q000150:complications; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D017713:Platelet Transfusion; D053657:Platelet-Rich Plasma; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000209:etiology / Q000628:therapy; D013921:Thrombocytopenia / Q000097:blood / Q000209:etiology / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents