title: Toxic effects of copper ion in zebrafish in the joint presence of CdTe QDs.
abstract: Quantum dots (QDs) have strong adsorption capacity; therefore, their potential toxicity of the facilitated transport of other trace toxic pollutants when they co-exist to aquatic organisms has become a hot research topic. The lab study was performed to determine the developmental toxicities to the zebrafish after exposed to the combined pollution of Cadmium-telluride (CdTe) QDs and copper ion (Cu(2+)) compared to the single exposure. Our findings for the first time revealed that: 1) CdTe QDs facilitated the accumulation of Cu(2+) in zebrafish, 2) the higher mortality, lower hatch rate, and more malformations can be clearly observed, 3) the diverse vascular hyperplasia, turbulence, and bifurcation of the exposed FLI-1 transgenic zebrafish larvae appeared together, 4) the synergistic effects played more important role during joint exposure. These observations provide a basic understanding of CdTe QDs and Cu(2+) joint toxicity to aquatic organisms.
authors: State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, East China University of Science and Technology, Shanghai 200237, PR China. wzhang@ecust.edu.cn
authors: Wei
authors: W
authors: Zhang
authors: Youna
authors: Y
authors: Miao
authors: Kuangfei
authors: K
authors: Lin
authors: Lin
authors: L
authors: Chen
authors: Qiaoxiang
authors: Q
authors: Dong
authors: Changjiang
authors: C
authors: Huang
mesh_terms: D000818:Animals; D019187:Cadmium Compounds / Q000633:toxicity*; D003300:Copper / Q000633:toxicity*; D045663:Quantum Dots; D018570:Risk Assessment; D013691:Tellurium / Q000633:toxicity*; D018675:Toxicity Tests; D014874:Water Pollutants, Chemical / Q000633:toxicity*; D015027:Zebrafish
chemical_list: D019187:Cadmium Compounds; D014874:Water Pollutants, Chemical; D003300:Copper; D013691:Tellurium; C028337:cadmium telluride