title: Clinical presentation and laboratory findings for the first autochthonous cases of dengue fever in Madeira island, Portugal, October 2012.
abstract: An outbreak of dengue fever in Madeira island was reported in 2012. Clinical and laboratory findings of the first two laboratory-confirmed autochthonous cases are reported. Both cases had fever (≥38 °C) and petechial rash. Symptoms also included myalgia, asthenia, nausea, vomiting, anorexia, diffuse abdominal pain, and diarrhoea. The two cases were confirmed by serology and one tested positive for a dengue viral sequence. Dengue virus serotype DEN-1 was identified with probable Central or South American origin.
authors: Centro de Estudos de Vectores e Doencas Infecciosas, Instituto Nacional de Saude Dr. Ricardo Jorge, Águas de Moura, Portugal. m.joao.alves@insa.min-saude.pt
authors: M J
authors: MJ
authors: Alves
authors: P L
authors: PL
authors: Fernandes
authors: F
authors: F
authors: Amaro
authors: H
authors: H
authors: Osório
authors: T
authors: T
authors: Luz
authors: P
authors: P
authors: Parreira
authors: G
authors: G
authors: Andrade
authors: L
authors: L
authors: Zé-Zé
authors: H
authors: H
authors: Zeller
mesh_terms: D000293:Adolescent; D000328:Adult; D000330:Aedes / Q000821:virology; D000818:Animals; D019411:Clinical Laboratory Techniques; D003715:Dengue / Q000175:diagnosis* / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D003716:Dengue Virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D010802:Phylogeny; D011174:Portugal / Q000453:epidemiology; D012367:RNA, Viral / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D017421:Sequence Analysis; D012703:Serotyping
chemical_list: D012367:RNA, Viral