title: Early and unexpectedly severe start of influenza epidemic in the Czech Republic during influenza season 2012-13.
abstract: A sudden increase in severe influenza has been registered in the Czech Republic since the end of 2012, with 264 cases requiring intensive care, including 51 deaths. Most patients had at least one risk factor. Severe influenza in patients with obesity, smoking and/or haematological disorders including haematological cancers was more frequent than in the pre-pandemic period. The seasonal influenza vaccination status of the cases indicates indirect efficiency of the current vaccine in preventing severe influenza.
authors: Department of Infectious Diseases Epidemiology, National Institute of Public Health, Prague, Czech Republic. jkyncl@szu.cz
authors: J
authors: J
authors: Kyncl
authors: M
authors: M
authors: Havlickova
authors: A
authors: A
authors: Nagy
authors: H
authors: H
authors: Jirincova
authors: I
authors: I
authors: Piskova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D018153:Czech Republic / Q000453:epidemiology; D058872:Epidemics; D005260:Female; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009980:Influenza A virus / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification*; D007252:Influenza Vaccines / Q000008:administration & dosage; D007251:Influenza, Human / Q000453:epidemiology* / Q000517:prevention & control* / Q000821:virology; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D011159:Population Surveillance; D012367:RNA, Viral / Q000235:genetics; D012307:Risk Factors; D012621:Seasons; D017422:Sequence Analysis, DNA; D012720:Severity of Illness Index; D013997:Time Factors; D055815:Young Adult
chemical_list: D007252:Influenza Vaccines; D012367:RNA, Viral