title: [Research progress in tissue engineered meniscus].
abstract: OBJECTIVE
  To elucidate the latest research progress and application of tissue engineered meniscus.
  
  
  METHODS
  The literature concerning the advance in tissue engineered meniscus was extensively reviewed, then closely-related issues including seed cells, scaffolds, and bioreactors were analyzed.
  
  
  RESULTS
  With more and more attention being paid to meniscus tissue engineering, different approaches and strategies for seed cells, scaffolds, and bioreactors have contributed to the generation of meniscal constructs, which are capable of restoring meniscal lesions to some extent, but translating successes in basic science research to clinical application is still limited.
  
  
  CONCLUSIONS
  More research for the optimal combination of the appropriate cell source, the scaffold type, and the proper physical and chemical factors for the stimulation of cells differentiation into tissue with optimal phenotypes in tissue engineered meniscus is still in needed, but the overall future looks promising.
authors: Department of Orthopedics, the 3rd Affiliated Hospital of Sun Yat-sen University, Guangzhou Guangdong, 510630, PR China.
authors: Shangfu
authors: S
authors: Li
authors: Limin
authors: L
authors: Rong
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D019149:Bioreactors; D018929:Cell Culture Techniques / Q000379:methods; D002478:Cells, Cultured; D019902:Chondrocytes / Q000166:cytology*; D006801:Humans; D008592:Menisci, Tibial / Q000601:surgery; D059630:Mesenchymal Stem Cells / Q000166:cytology; D012038:Regeneration / Q000502:physiology; D013234:Stem Cells / Q000166:cytology*; D000070600:Tibial Meniscus Injuries; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials