title: Association of the candidate gene SLC1A1 and obsessive-compulsive disorder in Han Chinese population.
abstract: This case-control study enrolled 578 obsessive-compulsive disorder (OCD) patients and 649 controls and genotyped rs10491734, rs2228622, rs301430 and rs301443 to replicate association of the SLC1A1 gene with OCD in ethnic Han Chinese. The G-A-C-G and G-G-T-C haplotypes were found to be significantly associated with OCD in overall samples, male samples and female samples.
authors: Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, 200030, Shanghai, China.
authors: Haisu
authors: H
authors: Wu
authors: Xuemei
authors: X
authors: Wang
authors: Shunying
authors: S
authors: Yu
authors: Dongxiang
authors: D
authors: Wang
authors: Jianhua
authors: J
authors: Chen
authors: Kaida
authors: K
authors: Jiang
authors: Liping
authors: L
authors: Zhu
authors: Zeping
authors: Z
authors: Xiao
authors: Drew
authors: D
authors: Fralick
mesh_terms: D044466:Asian People / Q000208:ethnology / Q000235:genetics; D016022:Case-Control Studies; D050580:Excitatory Amino Acid Transporter 3 / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease; D005838:Genotype; D006801:Humans; D015810:Linkage Disequilibrium; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000453:epidemiology / Q000208:ethnology / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*
chemical_list: D050580:Excitatory Amino Acid Transporter 3; C493400:SLC1A1 protein, human
keywords: Glutamate transporter gene; Haplotype; Obsessive–compulsive disorder