title: Central line associated blood stream infection related to cooling catheter in cardiac arrest survivors undergoing therapeutic hypothermia by endovascular cooling.
abstract: BACKGROUND
  The risk of central line associated blood stream infections (CLABSI) related to cooling catheters used for therapeutic hypothermia (TH) is unclear.
  
  
  METHODS
  We performed a retrospective analysis on 131 cardiac arrest survivors between 2007 and 2010, who underwent TH by femorally placed endovascular cooling catheter. All patients received prophylactic intravenous ampicillin-sulbactam for 72 hours to reduce the risk of aspiration pneumonia. Cooling catheter related CLABSI and other infections over a period of seven days from initiation of TH were estimated.
  
  
  RESULTS
  Of a total 131 patients, 16 (12%) patients had bacteremia or infection prior to initiation of TH and were excluded. Of the remaining 115 (88%) patients, zero (0%) patients had cooling catheter related CLABSI and 23 (20%) patients had other infections during the study period.
  
  
  CONCLUSIONS
  In cardiac arrest survivors undergoing TH, femorally placed endovascular cooling catheter is not associated with an increased incidence of CLABSI.
authors: Hartford Hospital, USA. nbpatel@harthosp.org
authors: Nishant
authors: N
authors: Patel
authors: Sanjeev U
authors: SU
authors: Nair
authors: Pampana
authors: P
authors: Gowd
authors: Ankur
authors: A
authors: Gupta
authors: David
authors: D
authors: Morris
authors: Giovanni G
authors: GG
authors: Geronilla
authors: Justin
authors: J
authors: Lundbye
mesh_terms: D000368:Aged; D000667:Ampicillin / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D055499:Catheter-Related Infections / Q000188:drug therapy / Q000209:etiology*; D002405:Catheterization, Central Venous / Q000009:adverse effects* / Q000379:methods; D003428:Cross Infection / Q000188:drug therapy / Q000209:etiology*; D057510:Endovascular Procedures; D005260:Female; D006323:Heart Arrest / Q000628:therapy*; D006801:Humans; D007036:Hypothermia, Induced / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018805:Sepsis / Q000188:drug therapy / Q000209:etiology*; D013407:Sulbactam / Q000008:administration & dosage
chemical_list: D000900:Anti-Bacterial Agents; C035444:sultamicillin; D000667:Ampicillin; D013407:Sulbactam