title: The use of psychotropic agents for the symptoms of obsessive-compulsive disorder.
abstract: OBJECTIVE
  To describe the use of psychotropic agents in a sample of subjects with obsessive-compulsive disorder (OCD), and in particular the differences associated with different OCD symptoms.
  
  
  METHODS
  A total of 154 subjects participated in a study assessing OCD symptom subtypes, called the Nepean OCD Study. In addition to a comprehensive evaluation of the subjects' OCD symptoms using the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Vancouver Obsessive-Compulsive Inventory (VOCI), and the Sheehan Disability Scale (SDS), the subjects' medication history was recorded. The association between symptom severity, disability, OCD symptom subtypes and the use of psychotropic agents was examined.
  
  
  RESULTS
  Psychotropic medication was taken by 93 (60.4%) participants. In the majority of cases (n=55, 59.1%), selective serotonin reuptake inhibitors (SSRIs) were taken, and of the SSRIs, the most commonly used agent was escitalopram (n=21, 22.6%). Psychotropic agents were more likely to be taken by subjects with higher Y-BOCS and SDS scores. Hoarding was associated with a lower likelihood of psychotropic use, whereas unacceptable/taboo thoughts were associated with an increased likelihood of psychotropic and antipsychotic use.
  
  
  CONCLUSIONS
  Patients with OCD are more likely to be taking psychotropic agents if they have a more severe illness, greater disability and more prominent unacceptable/taboo thoughts.
authors: University of Sydney, Sydney Medical School (Nepean), Penrith, NSW, Australia. vlasios.brakoulias@sydney.edu.au
authors: Vlasios
authors: V
authors: Brakoulias
authors: Vladan
authors: V
authors: Starcevic
authors: David
authors: D
authors: Berle
authors: Denise
authors: D
authors: Milicevic
authors: Karen
authors: K
authors: Moses
authors: Anthony
authors: A
authors: Hannan
authors: Peter
authors: P
authors: Sammut
authors: Andrew
authors: A
authors: Martin
mesh_terms: D000293:Adolescent; D000328:Adult; D004363:Drug Utilization; D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000188:drug therapy*; D011569:Psychiatric Status Rating Scales; D011619:Psychotropic Drugs / Q000627:therapeutic use*
chemical_list: D011619:Psychotropic Drugs