title: Cell to extracellular matrix interactions and their reciprocal nature in cancer.
abstract: Interactions between the cell and the extracellular matrix (ECM) are critical in controlling the fate and behaviour of cancer cells. Alterations in either the ECM or in cellular events affect this interaction. In this mini-review we give an overview of the role of cell-ECM interactions in cancer, with a particular focus on the reciprocal nature of the cell-ECM interactions and how this contributes to cancer progression.
authors: Karolinska Institutet, Department of Biosciences and Nutrition, Huddinge SE-141 83, Sweden. Electronic address: marianne.van.dijk@ki.se.
authors: Marianne
authors: M
authors: van Dijk
authors: Karolinska Institutet, Department of Biosciences and Nutrition, Huddinge SE-141 83, Sweden.
authors: Sara A
authors: SA
authors: Göransson
authors: Karolinska Institutet, Department of Biosciences and Nutrition, Huddinge SE-141 83, Sweden. Electronic address: staffan.stromblad@ki.se.
authors: Staffan
authors: S
authors: Strömblad
mesh_terms: D000818:Animals; D002450:Cell Communication; D002468:Cell Physiological Phenomena; D005109:Extracellular Matrix / Q000473:pathology*; D006801:Humans; D009369:Neoplasms / Q000473:pathology*
keywords: Contraction; ECM; Integrin; Remodelling; Stiffness; Tension