title: Association of abdominal obesity with lumbar disc degeneration--a magnetic resonance imaging study.
abstract: OBJECTIVE
  To evaluate whether midsagittal (abdominal) obesity in magnetic resonance imaging (MRI), waist circumference (WC) and body fat percentage are associated with lumbar disc degeneration in early adulthood.
  
  
  METHODS
  We obtained the lumbar MRI (1.5-T scanner) of 325 females and 233 males at a mean age of 21 years. Lumbar disc degeneration was evaluated using Pfirrmann classification. We analysed the associations of MRI measures of obesity (abdominal diameter (AD), sagittal diameter (SAD), ventral subcutaneous thickness (VST), and dorsal subcutaneous thickness (DST)), WC and body fat percentage with disc degeneration sum scores using ordinal logistic regression.
  
  
  RESULTS
  A total of 155 (48%) females and 147 (63%) males had disc degeneration. AD and SAD were associated with a disc degeneration sum score of ≥3 compared to disc degeneration sum score of 0-2 (OR 1.67; 95% confidence interval (CI) 1.20-2.33 and OR 1.40; 95% CI 1.12-1.75, respectively) among males, but we found no association among females. WC was also associated with disc degeneration among males (OR 1.03 per one cm; 95% CI 1.00-1.05), but not among females.
  
  
  CONCLUSIONS
  Measures of abdominal obesity in MRI and waist circumference were associated with disc degeneration among 21-year-old males.
authors: Institute of Clinical Medicine, University of Oulu, Oulu, Finland. jani.takatalo@fimnet.fi
authors: Jani
authors: J
authors: Takatalo
authors: Jaro
authors: J
authors: Karppinen
authors: Simo
authors: S
authors: Taimela
authors: Jaakko
authors: J
authors: Niinimäki
authors: Jaana
authors: J
authors: Laitinen
authors: Roberto Blanco
authors: RB
authors: Sequeiros
authors: Dino
authors: D
authors: Samartzis
authors: Raija
authors: R
authors: Korpelainen
authors: Simo
authors: S
authors: Näyhä
authors: Jouko
authors: J
authors: Remes
authors: Osmo
authors: O
authors: Tervonen
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000000981:diagnostic imaging* / Q000209:etiology; D016015:Logistic Models; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D056128:Obesity, Abdominal / Q000150:complications / Q000000981:diagnostic imaging*; D016017:Odds Ratio; D011859:Radiography; D012307:Risk Factors; D012737:Sex Factors; D055105:Waist Circumference; D055815:Young Adult