title: Effectiveness and efficiency of assertive outreach for Schizophrenia in Germany: study protocol on a pragmatic quasi-experimental controlled trial.
abstract: BACKGROUND
  A model of assertive outreach (AO) in which office-based psychiatrists collaborate with ambulatory nursing services for providing intensive home-treatment is currently being implemented in rural areas of Lower Saxony, Germany. The costs of the model are reimbursed by some of the statutory health insurance companies active in Lower Saxony. Effectiveness and efficiency of this model for patients suffering from schizophrenia is evaluated in a pragmatic and prospective trial.
  
  
  METHODS
  Quasi-experimental controlled trial: patients receiving the intervention are all those receiving AO; controls are patients not eligible for AO based on their health insurance affiliation.
  
  
  METHODS
  clinical diagnosis of schizophrenia (ICD-10 F.20), aged at least 18 years and being moderately to severely impaired in global functioning.
  
  
  METHODS
  admission and days spent in psychiatric inpatient care; secondary outcomes: clinical and functional status; patient satisfaction with chronic care; health care costs. Follow-up time: 6 and 12 months.
  
  
  CONCLUSIONS
  The study faces many challenges typical to pragmatic trials such as the rejection of randomisation by service providers, the quality of treatment as usual (TAU) to which the intervention will be compared, and the impairment of the study subjects. Solutions of how to deal with these challenges are presented and discussed in detail.
  
  
  BACKGROUND
  International Standard Randomised Controlled Trial Number: http://ISRCTN34900108, German Clinical Trial Register: http://DRKS00003351.
authors: Innovation Incubator, Leuphana University Luneburg, Luneburg, Germany.
authors: Anke
authors: A
authors: Bramesfeld
authors: Jörn
authors: J
authors: Moock
authors: Kirsten
authors: K
authors: Kopke
authors: Dorothea
authors: D
authors: Büchtemann
authors: Denise
authors: D
authors: Kästner
authors: Jeanett
authors: J
authors: Radisch
authors: Wulf
authors: W
authors: Rössler
mesh_terms: D002985:Clinical Protocols; D003156:Community Mental Health Services / Q000191:economics / Q000379:methods*; D003362:Cost-Benefit Analysis; D005858:Germany; D006801:Humans; D008134:Long-Term Care; D010045:Outpatients / Q000523:psychology*; D017060:Patient Satisfaction; D012107:Research Design; D012559:Schizophrenia / Q000191:economics / Q000628:therapy*