title: An efficient chemoselective reduction of furan series unsaturated dinitriles.
abstract: An efficient reduction of double bonds conjugated with nitrile groups and acid or base sensitive furan rings with 2-phenylbenzimidazoline generated in situ has been successfully accomplished with high yields and excellent selectivity. The employed reducing agent was prepared in one step from ordinary chemicals. The other advantages of the presented method include mild and convenient reaction conditions, a benign and cost effective reagent, simple work-up and separation of the products. As this process does neither affect cyano and nitro groups nor furan rings, it is a valuable alternative when  metal-catalyzed hydrogenations or borohydride reductions have failed.
authors: Department of Chemical Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho 1/3, 61242 Brno, Czech Republic. bobalp@vfu.cz
authors: Pavel
authors: P
authors: Bobal
authors: Janette
authors: J
authors: Bobalova
mesh_terms: D005663:Furans / Q000138:chemical synthesis / Q000737:chemistry*; D009570:Nitriles / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D005663:Furans; D009570:Nitriles; C039281:furan