title: [Circulating immune complexes, heat shock proteins in the serum of smoking allergy sufferers--preliminary results].
abstract: Circulating immune complexes (CIC) rises in response to immunogens appearing in human body. An increasing of the CIC concentration is observed in allergies as well as many others diseases. As a result of inflammatory process localized within intracellular space heat shock proteins (HSP) may occur. The aim of work was the CIC levels estimation as well as CIC HSP-70 presence analysis in serum of smoking and non-smoking allergy sufferers. Serum from 12 smoking and 15 non-smoking patients were examined. Serum from 34 healthy persons constituted the control group. The level of CIC was established by Haskowa precipitation method. The identification of HSP-70 antigen within CIC was determined by Dot blot method. We discovered increased CIC levels in serum from smoking allergy sufferers in comparison with non-smokers. The highest percentage of HSP-70 presence within CIC was observed in smoking allergy sufferers.
authors: Zakład Biochemii i Biologii Komórki, Instytut Biologii Eksperymentalnej, UKW w Bydgoszczy. goldar@ukw.edu.pl
authors: Ryszard
authors: R
authors: Gołda
authors: Grzegorz
authors: G
authors: Przybylski
authors: Wojciech
authors: W
authors: Jóźwicki
authors: Małgorzata
authors: M
authors: Wyszomirska
mesh_terms: D000328:Adult; D000936:Antigen-Antibody Complex / Q000097:blood*; D006360:Heat-Shock Proteins / Q000097:blood*; D006801:Humans; D006967:Hypersensitivity / Q000097:blood / Q000276:immunology*; D008875:Middle Aged; D012016:Reference Values; D044967:Serum / Q000276:immunology; D012907:Smoking / Q000009:adverse effects* / Q000097:blood / Q000276:immunology*; D055815:Young Adult
chemical_list: D000936:Antigen-Antibody Complex; D006360:Heat-Shock Proteins