title: Synthesis of LipidGreen2 and its application in lipid and fatty liver imaging.
abstract: We have developed LipidGreen2, a second generation small molecule probe for lipid imaging. LipidGreen2 has a better fluorescence signal compared with the previous LipidGreen, and selectively stains neutral lipids in cells and fat deposits in live zebrafish. We also demonstrate the application of LipidGreen2 for detecting fatty liver.
authors: Bioorganic Science Division, Korea Research Institute of Chemical Technology, Jang-Dong 100, Yuseong, Daejeon, 305-600, South Korea.
authors: Hang-Suk
authors: HS
authors: Chun
authors: Jong Hyun
authors: JH
authors: Jeon
authors: Haushabhau S
authors: HS
authors: Pagire
authors: Jae Hong
authors: JH
authors: Lee
authors: Hee-Chung
authors: HC
authors: Chung
authors: Myoung Joo
authors: MJ
authors: Park
authors: Ju-Hoon
authors: JH
authors: So
authors: Jae-Ho
authors: JH
authors: Ryu
authors: Cheol-Hee
authors: CH
authors: Kim
authors: Jin Hee
authors: JH
authors: Ahn
authors: Myung Ae
authors: MA
authors: Bae
mesh_terms: D000818:Animals; D002460:Cell Line; D005234:Fatty Liver / Q000175:diagnosis*; D005456:Fluorescent Dyes / Q000737:chemistry; D006801:Humans; D008055:Lipids / Q000138:chemical synthesis / Q000737:chemistry*; D051379:Mice; D057054:Molecular Imaging / Q000379:methods; D015335:Molecular Probes / Q000737:chemistry*; D015027:Zebrafish
chemical_list: D005456:Fluorescent Dyes; D008055:Lipids; D015335:Molecular Probes