title: Evaluation of gastrectomy in patients with delayed gastric emptying after antireflux surgery or large hiatal hernia repair.
abstract: BACKGROUND
  Revision antireflux surgery and large hiatal hernia repair require extensive dissection at the gastroesophageal junction. This may lead to troublesome symptoms due to delayed gastric emptying, eventually requiring gastrectomy. The aim of this study was to evaluate the outcome of gastrectomy for severely delayed gastric emptying after large hiatal hernia repair or redo antireflux surgery.
  
  
  METHODS
  Eleven patients were treated between 1995 and 2010 and entered in the study. Preoperative and operative data were retrospectively collected. Standardized questionnaires were sent to all of the patients to evaluate symptomatic outcome.
  
  
  RESULTS
  The primary intervention was Nissen fundoplication in nine patients, Toupet fundoplication in one, and cruroplasty in another. The repairs were for refractory gastroesophageal reflux disease in five patients and a symptomatic large hiatal hernia in six. Subsequent gastrectomy was partial in four patients, subtotal in six, and total in one. There was one minor postoperative complication. After a mean (±SD) duration of 102 ± 59 months, nine patients were available for symptomatic follow-up. Eight patients experienced daily symptoms related to dumping. Daily symptoms indicative of delayed gastric emptying were present in seven patients at follow-up. Mean general quality of life was increased from 3.8 ± 2.2 before gastrectomy to 5.4 ± 1.8 at follow-up. Eight patients reported gastrectomy as worthwhile.
  
  
  CONCLUSIONS
  Gastrectomy after previous antireflux surgery or large hiatal hernia repair is safe with the potential to improve quality of life. Although upper gastrointestinal symptoms tend to persist, gastrectomy can be considered a reasonable, last-resort surgical option for alleviating upper gastrointestinal symptoms after this kind of surgery.
authors: Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
authors: Arja
authors: A
authors: Gerritsen
authors: Edgar J B
authors: EJ
authors: Furnée
authors: Hein G
authors: HG
authors: Gooszen
authors: Maurits
authors: M
authors: Wondergem
authors: Eric J
authors: EJ
authors: Hazebroek
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D018662:Fundoplication / Q000379:methods; D005743:Gastrectomy / Q000379:methods; D005746:Gastric Emptying; D005764:Gastroesophageal Reflux / Q000601:surgery; D006551:Hernia, Hiatal / Q000601:surgery; D059685:Herniorrhaphy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000601:surgery*; D011788:Quality of Life; D012086:Reoperation; D012189:Retrospective Studies; D013272:Stomach Diseases / Q000209:etiology / Q000601:surgery*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome