title: Resistant oral mucosal lesions in pemphigus vulgaris responsive to double filtration plasmapheresis: First case report from Turkey.
abstract: BACKGROUND
  Adjuvant therapeutic methods are employed when pemphigus vulgaris (PV) fails to be controlled by conventional corticosteroid treatment.
  
  
  OBJECTIVE
  The efficacy of double filtration plasmapheresis (DFPP) was investigated in a PV patient with severe, refractory mucosal disease.
  
  
  METHODS
  A total of 3 DFPP cycles, each cycle consisting of 5 double filtration sessions conducted on alternate days was completed.
  
  
  RESULTS
  DFPP provided immediate clinical relief of symptoms as well as a significant decrease in anti-desmoglein antibody levels and allowed for a much lower corticosteroid dose.
  
  
  CONCLUSIONS
  DFPP was an effective and safe adjuvant therapy in our patient with PV and it offers a valid treatment option in PV patients with recalcitrant disease.
authors: Adnan Menderes University, Department of Dermatology, Turkey. esavk@adu.edu.tr
authors: E
authors: E
authors: Savk
authors: M
authors: M
authors: Uslu
authors: I
authors: I
authors: Yavaşoğlu
authors: G
authors: G
authors: Kadıköylü
authors: N
authors: N
authors: Sendur
authors: G
authors: G
authors: Karaman
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D003893:Desmin / Q000276:immunology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009059:Mouth Diseases / Q000097:blood / Q000276:immunology / Q000473:pathology / Q000628:therapy; D009061:Mouth Mucosa / Q000276:immunology / Q000378:metabolism / Q000473:pathology; D010392:Pemphigus / Q000097:blood / Q000276:immunology / Q000473:pathology / Q000628:therapy; D010956:Plasmapheresis; D014421:Turkey
chemical_list: D000305:Adrenal Cortex Hormones; D001323:Autoantibodies; D003893:Desmin