title: Parkinson's disease: recent advances.
abstract: Parkinson's disease is most common degenerative disorder. Diagnosis is clinical in majority of the patients. Small number of patients have family history and several types of familial Parkinson's disease is now known. Most of the patients have onset of symptoms in sixth decade. Response to dopa agonists and L-dopa is good and there are different reasons to choose any of the drug as first line treatment. Motor fluctuation presenting as wearing off and dyskinesias are main challenges in long term management.
authors: Department of Neurology, GB Pant Hospital, Delhi.
authors: Sanjay
authors: S
authors: Pandey
mesh_terms: D000978:Antiparkinson Agents / Q000627:therapeutic use; D001921:Brain / Q000601:surgery; D003863:Depression / Q000150:complications / Q000188:drug therapy; D018491:Dopamine Agonists / Q000627:therapeutic use; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D010300:Parkinson Disease / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics / Q000628:therapy*
chemical_list: D000978:Antiparkinson Agents; D018491:Dopamine Agonists; D007980:Levodopa