title: Predictors of cognitive decline in 85-year-old patients without cognitive impairment at baseline: 2-year follow-up of the octabaix study.
abstract: BACKGROUND
  To determine how many 85-year-old community-dwelling patients with good cognitive performance at baseline maintain this level at 2-year follow-up.
  
  
  METHODS
  We realized a longitudinal community-based study including 169 inhabitants. Patients who maintained scores >23 on the Spanish version of the Mini-Mental State Examination (MEC) were compared with the rest.
  
  
  RESULTS
  A total of 144 individuals (85.2%) were found maintaining a MEC score >23. Under the combined criteria 110 (65%) presented no new cognitive decline. Multiple logistic regression analysis showed that maintaining a MEC score >23 was significantly associated with having a higher MEC score at baseline (P < .001, odds ratio 1.280, 95% confidence interval 1.104-1.484).
  
  
  CONCLUSIONS
  Most oldest-old patients with good cognitive function at baseline maintain this level at 2-year follow-up.
authors: Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain. fformiga@bellvitgehospital.cat
authors: Francesc
authors: F
authors: Formiga
authors: Assumpta
authors: A
authors: Ferrer
authors: David
authors: D
authors: Chivite
authors: Jesus
authors: J
authors: Alburquerque
authors: Claudia
authors: C
authors: Olmedo
authors: Jose Maria
authors: JM
authors: Mora
authors: María
authors: M
authors: Labori
authors: Ramón
authors: R
authors: Pujol
mesh_terms: D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology / Q000523:psychology*; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000175:diagnosis*; D015331:Cohort Studies; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D015577:Geriatric Assessment; D006801:Humans; D016015:Logistic Models; D008297:Male; D008609:Mental Status Schedule; D011446:Prospective Studies; D012307:Risk Factors