title: Tracking X-ray microscopy for alveolar dynamics in live intact mice.
abstract: Here we report a tracking X-ray microscopy (TrXM) as a novel methodology by using upper right lung apices alveoli in live intact mice. By enabling tracking of individual alveolar movements during respiration, TrXM identifies alveolar dynamics: individual alveoli in the upper lung apices show a small size increment as 4.9 ± 0.4% (mean ± s.e.m.) during respiration while their shapes look almost invariant. TrXM analysis in alveolar dynamics would be significant for better understanding of alveolar-based diseases, for instance, ventilator induced lung injury (VILI) in acute respiratory distress syndrome (ARDS).
authors: X-ray Imaging Center, Pohang University of Science and Technology, Hyoja-dong, Pohang, Korea.
authors: Soeun
authors: S
authors: Chang
authors: Namseop
authors: N
authors: Kwon
authors: Byung Mook
authors: BM
authors: Weon
authors: Jinkyung
authors: J
authors: Kim
authors: Chin Kook
authors: CK
authors: Rhee
authors: Han Sung
authors: HS
authors: Choi
authors: Yoshiki
authors: Y
authors: Kohmura
authors: Masaki
authors: M
authors: Yamamoto
authors: Tetsuya
authors: T
authors: Ishikawa
authors: Jung Ho
authors: JH
authors: Je
mesh_terms: D000818:Animals; D055370:Lung Injury / Q000503:physiopathology; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D011650:Pulmonary Alveoli / Q000000981:diagnostic imaging* / Q000502:physiology; D011859:Radiography; D012128:Respiratory Distress Syndrome / Q000503:physiopathology; D059008:Time-Lapse Imaging