title: Highly sensitive detection of telomerase based on a DNAzyme strategy.
abstract: The present study demonstrated a highly sensitive strategy for measuring telomerase activity in cell extracts. Furthermore, we applied the new strategy for in situ detection of telomerase at the cellular level in cancer cells, together with a normal cell as the negative control.
authors: College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, Wuhan University, Wuhan, Hubei 430072, PR China.
authors: Tian
authors: T
authors: Tian
authors: Shuang
authors: S
authors: Peng
authors: Heng
authors: H
authors: Xiao
authors: Xiaoe
authors: X
authors: Zhang
authors: Shan
authors: S
authors: Guo
authors: Shaoru
authors: S
authors: Wang
authors: Xiang
authors: X
authors: Zhou
authors: Songmei
authors: S
authors: Liu
authors: Xin
authors: X
authors: Zhou
mesh_terms: D045744:Cell Line, Tumor; D021881:DNA, Catalytic / Q000378:metabolism*; D004789:Enzyme Activation; D006367:HeLa Cells; D006801:Humans; D018613:Microscopy, Confocal; D008856:Microscopy, Fluorescence; D012680:Sensitivity and Specificity; D019098:Telomerase / Q000235:genetics / Q000378:metabolism*; D013997:Time Factors
chemical_list: D021881:DNA, Catalytic; D019098:Telomerase