title: [The influence of chromium chloride consumption on peroxidation processes and activity of antioxidant defence in rat tissues].
abstract: The supplementation of a standart vivarium food with 200 mg/kg CrCl3 x 6H2O caused an increase in chromium content and a decrease in hydroperoxide and TBARS in most tissues examined. Also in all organs and tissues of rats the activity of glutathione peroxidase, glutathione reductase and catalase incresed at action of chromium increased. In brain and kidneys the level of reduced glutathione increased. Superoxide dismutase activity was significantly higher in heart and skeletal muscles of animals and equal in lungs and liver, and in other organs--brain, kidneys and spleen in animals of the studied group the enzyme activity was lower compared to animals of control group. These results demonstrate the regulatory influence of chromium on free radical process in rat tissues.
authors: R Ia
authors: RIa
authors: Iskra
authors: V G
authors: VG
authors: Ianovich
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism* / Q000494:pharmacology*; D002712:Chlorides / Q000494:pharmacology*; D017608:Chromium Compounds / Q000494:pharmacology*; D019587:Dietary Supplements; D005609:Free Radicals / Q000378:metabolism*; D008297:Male; D009928:Organ Specificity / Q000187:drug effects / Q000502:physiology; D010088:Oxidoreductases / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000975:Antioxidants; D002712:Chlorides; D017608:Chromium Compounds; D005609:Free Radicals; C017133:chromous chloride; D010088:Oxidoreductases