title: Efficacy of a topical cosmetic slimming treatment for postmenopausal women: a randomized, double-blind, placebo controlled trial.
abstract: OBJECTIVE
  The aim of this paper was to evaluate by clinical and non-invasive instrumental evaluations, the efficacy and the tolerance of a cosmetic slimming treatment for menopausal women used topically (for at least 3 years) under dermatological control.
  
  
  METHODS
  A controlled double blind, randomised study was performed to compare the slimming efficacy of the cosmetic slimming treatment versus placebo after 4 weeks of treatment.
  
  
  RESULTS
  Cosmetic slimming treatment twice a day for 4 weeks reduced abdomen and hips fat, with no significant variation in body weight in comparison with the placebo.
  
  
  CONCLUSIONS
  The present study evidenced the clinical effectiveness and women satisfaction of a slimming treatment specifically studies for postmenopausal adipose tissue with potential interesting consequences on measures of quality of life and on health-care programs.
authors: Division of Gynecology and Obstetrics, Department of Reproductive Medicine and Child Development, University of Pisa, Pisa, Italy. nicola.pluchino@med.unipi.it
authors: N
authors: N
authors: Pluchino
authors: A N
authors: AN
authors: Santoro
authors: A
authors: A
authors: Sparavigna
authors: R
authors: R
authors: Vesnaver
authors: A
authors: A
authors: Cenni
authors: M
authors: M
authors: Oliva
authors: A R
authors: AR
authors: Genazzani
mesh_terms: D000273:Adipose Tissue / Q000601:surgery*; D000368:Aged; D003357:Cosmetic Techniques; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000601:surgery*; D017698:Postmenopause; D019651:Plastic Surgery Procedures