title: Paragonimiasis in chinese children: 58 cases analysis.
abstract: OBJECTIVE
  To analyze the clinical and radiological features of paragonimiasis in children and raise the awareness of this disease.
  
  
  METHODS
  A total of 58 paragonimiasis patients were reviewed. They were 42 boys and 16 girls aged 2.0 to 15.3 years.
  
  
  RESULTS
  Among these patients, 20 were diagnosed in the recent 5 years, 46 with a history of raw water or food ingestion. Except 2 patients without any complaint, the most common features involved the systemic (41, 70.7%) and respiratory systems (43, 74.1%), followed by abdominal, cardiac and nervous systems, with rash and mass. Eosinophilia was noted in 46 (79.3%) patients, granulocytosis in 45 (77.6%), anemia in 14 (24.1%), and thrombocytopenia in 3. Imageology showed pneumonia in 26 (44.8%) patients, pleurisy in 28 (48.3%), hydropericardium in 17 (29.3%), ascites in 16 (27.6%), and celiac lymphadenitis in 13 (22.4%). Besides hepatomegaly and splenomegaly, calcification and multiple lamellar low echogenic areas in the liver were noted, each in one patient. Abnormal brain imaging was noted in 4 of 10 patients. Karyocyte hyperplasia with eosinophilia was noted in all the 19 patients who received bone marrow puncture.
  
  
  CONCLUSIONS
  Paragonimiasis should be considered in the differential diagnosis of patients with multiple organs or system lesions, especially those with eosinophilia, serous cavity effusion, respiratory, cardiac, digestive system, nervous system abnormality, and/or mass. Healthy eating habit is helpful for paragonimiasis prevention.
authors: Department of Pulmonology, The Children's Hospital of Zhejiang University School of Medicine and the Key Laboratory of Reproductive Genetics (Zhejiang University), Ministry of Education, China.
authors: Hong Zhen
authors: HZ
authors: Xu
authors: Lan Fang
authors: LF
authors: Tang
authors: Xiao Ping
authors: XP
authors: Zheng
authors: Zhi Min
authors: ZM
authors: Chen
keywords: China; Eosinophilia; Metacercariae; Paragonimiasis; Paragonimus