title: [Cryptococcosis in renal transplant recipients].
abstract: This article presented the case of a 64 years-old renal transplant recipient, who was a poultry farm worker and had suffered meningoencephalitis six months after receiving immunosuppressive therapy. Rapid diagnosis was based on a cerebrospinal fluid sample analyzed with latex particles for Cryptococcus spp antigen detection. Culture of the clinical sample in agar-Sabouraund-chloramphenicol medium confirmed the initial diagnosis whereas biochemical identification was made with the API 20C AUX system. Amphotericin B treatment was immediately applied to the patient and later fluconazole until microbiological tests yielded negative results. After 5 months, the patient relapsed and restarted the specific treatment. He was followed up on outpatient service and two year after the organ transplantation, his recovery was favourable.
authors: Centro De Investigaciones Médico Quirúrgicas, Ciudad de La Habana. ipaneque@cimeq.sld.cu
authors: Ileana
authors: I
authors: Paneque Rodríguez
authors: Julio
authors: J
authors: Valdivia
authors: Aily
authors: A
authors: Aguiar Agramante
authors: Idania
authors: I
authors: Castillo Castillo
authors: Margot
authors: M
authors: Martínez Arroyo
authors: Ernesto
authors: E
authors: Delgado Almora
mesh_terms: D000666:Amphotericin B / Q000494:pharmacology / Q000627:therapeutic use; D000822:Animal Husbandry; D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use; D003455:Cryptococcus neoformans / Q000187:drug effects / Q000302:isolation & purification; D004197:Disease Reservoirs; D015725:Fluconazole / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects; D016030:Kidney Transplantation; D008297:Male; D016919:Meningitis, Cryptococcal / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000209:etiology*; D008875:Middle Aged; D009784:Occupational Diseases / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology; D016273:Occupational Exposure; D009894:Opportunistic Infections / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology; D011200:Poultry / Q000382:microbiology; D012008:Recurrence
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B; D015725:Fluconazole