title: Exonic resequencing of the DLGAP3 gene as a candidate gene for schizophrenia.
abstract: We resequenced the exonic regions of the DLGAP3 gene, which encodes SAP90/PSD95-associated protein 3, in 215 schizophrenic patients and 215 non-psychotic controls. Seven known single-nucleotide polymorphisms (SNPs) were identified, but not associated with schizophrenia. Nevertheless, we identified several rare missense mutations and some of them might be associated with the pathogenesis of schizophrenia.
authors: Department of Psychiatry, Taoyuan Armed Forces General Hospital, Taoyuan, Taiwan.
authors: Jun-Ming
authors: JM
authors: Li
authors: Chao-Lin
authors: CL
authors: Lu
authors: Min-Chih
authors: MC
authors: Cheng
authors: Sy-Ueng
authors: SU
authors: Luu
authors: Shih-Hsin
authors: SH
authors: Hsu
authors: Chia-Hsiang
authors: CH
authors: Chen
mesh_terms: D000328:Adult; D044466:Asian People / Q000235:genetics; D005091:Exons / Q000235:genetics*; D005260:Female; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D020125:Mutation, Missense / Q000235:genetics; D009419:Nerve Tissue Proteins / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics; D012559:Schizophrenia / Q000235:genetics*
chemical_list: C543515:DLGAP3 protein, human; D009419:Nerve Tissue Proteins