title: Pediatric extranodal marginal zone B-cell lymphoma presenting as amyloidosis in minor salivary glands: a case report and review of the literature.
abstract: We report an unusual case of an extranodal marginal zone B-cell lymphoma (EMZL) arising in the labial minor salivary gland in an immunocompetent 11-year-old boy. The initial histopathologic review favored localized amyloidosis. However, further evaluation supported the diagnosis of low-grade B-cell lymphoma with plasmacytic differentiation, surrounded by deposits of AL κ-type amyloid. Clinical management consisted of excision with no recurrence at 1-year follow-up. This case demonstrates that a diagnosis of lymphoma must be considered in cases of amyloidosis associated with minor salivary gland involvement, even in children. In addition, we provide a literature review of extranodal marginal zone B-cell lymphoma arising in salivary glands.
authors: Department of Pathology, School of Medicine, University of Michigan, Ann Arbor, MI 48109-1078, USA.
authors: Ali
authors: A
authors: Gabali
authors: Charles W
authors: CW
authors: Ross
authors: Paul C
authors: PC
authors: Edwards
authors: Bertram
authors: B
authors: Schnitzer
authors: Theodora E
authors: TE
authors: Danciu
mesh_terms: D000686:Amyloidosis / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D008048:Lip Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D008297:Male; D012196:Review Literature as Topic; D012470:Salivary Glands, Minor / Q000473:pathology*