title: Emerging role of colloidal drug delivery systems (CDDS) in NSAID topical administration.
abstract: NSAIDs are the most commonly prescribed category of drugs for the treatment of musculoskeletal pain and inflammation associated with many conditions. Topical administration of these drugs is always the best choice since adverse effects occur commonly with systemic NSAID therapy. Colloidal drug delivery systems (CDDS) are interesting systems, which are able to improve the duration of drug residence in the skin and to allow an achievable drug sustained and controlled release compared to conventional topical formulations. This review focuses on micro and nanoemulsions, vesicular carriers and nanoparticles as novel high efficiency delivery systems of NSAIDs in topical applications.
authors: Department of Drug Sciences, University of Catania, Viale Andrea Doria n°6 95125 Catania, Italy. capuglia@unict.it
authors: Carmelo
authors: C
authors: Puglia
authors: Giorgia Giusy
authors: GG
authors: Tirendi
authors: Francesco
authors: F
authors: Bonina
mesh_terms: D000287:Administration, Topical; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage* / Q000737:chemistry; D003102:Colloids / Q000008:administration & dosage* / Q000737:chemistry; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D003102:Colloids