title: Histological findings following use of CoSeal in a patient with a left ventricular assist device.
abstract: Adhesions are a formidable challenge in patients undergoing reoperative cardiac surgery, particularly in those supported by an intracorporeal left ventricular assist device (LVAD) and undergoing heart transplantation. This report describes the pathological findings following the clinical use of a surgical sealant (CoSeal, Baxter Healthcare, Fremont, CA), in a patient who underwent LVAD implantation. On the treated surfaces, a minimal amount of adhesions were observed, whereas in untreated surfaces adhesions were present.
authors: 1Department of Cardiac Surgery, Niguarda Ca' Granda Hospital, Milan, Italy.
authors: Aldo
authors: A
authors: Cannata
authors: Duccio
authors: D
authors: Petrella
authors: Marcello
authors: M
authors: Gambacorta
authors: Claudio F
authors: CF
authors: Russo
authors: Giuseppe
authors: G
authors: Bruschi
authors: Luigi
authors: L
authors: Martinelli
mesh_terms: D017809:Fatal Outcome; D006352:Heart Ventricles / Q000033:anatomy & histology / Q000187:drug effects / Q000601:surgery*; D006353:Heart-Assist Devices; D006651:Histocytochemistry; D006801:Humans; D008223:Lymphoma; D008297:Male; D008875:Middle Aged; D011092:Polyethylene Glycols / Q000009:adverse effects / Q000627:therapeutic use*; D014014:Tissue Adhesives / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: C513322:CoSeal; D014014:Tissue Adhesives; D011092:Polyethylene Glycols
keywords: SILS/ single site surgery; biomedical engineering; the business of surgery