title: Molecular archeology: unearthing androgen-induced structural rearrangements in prostate cancer genomes.
abstract: In this issue of Cancer Cell, Weischenfeldt and colleagues report on the whole genome sequencing of 11 early-onset prostate cancers. Compared to elderly onset prostate cancer, these tumors demonstrate enrichment for androgen-driven structural rearrangements involving ETS family genes. This study confirms observations that prostate cancer manifests discrete genomic subclasses.
authors: Centre for Integrative Biology, University of Trento, Povo, Trento, 38123, Italy.
authors: Francesca
authors: F
authors: Demichelis
authors: Levi A
authors: LA
authors: Garraway
authors: Mark A
authors: MA
authors: Rubin