title: Exercise-induced muscle damage and running economy in humans.
abstract: Running economy (RE), defined as the energy demand for a given velocity of submaximal running, has been identified as a critical factor of overall distance running performance. Plyometric and resistance trainings, performed during a relatively short period of time (~15-30 days), have been successfully used to improve RE in trained athletes. However, these exercise types, particularly when they are unaccustomed activities for the individuals, may cause delayed onset muscle soreness, swelling, and reduced muscle strength. Some studies have demonstrated that exercise-induced muscle damage has a negative impact on endurance running performance. Specifically, the muscular damage induced by an acute bout of downhill running has been shown to reduce RE during subsequent moderate and high-intensity exercise (>65% VO₂max). However, strength exercise (i.e., jumps, isoinertial and isokinetic eccentric exercises) seems to impair RE only for subsequent high-intensity exercise (~90% VO₂max). Finally, a single session of resistance exercise or downhill running (i.e., repeated bout effect) attenuates changes in indirect markers of muscle damage and blunts changes in RE.
authors: Human Performance Laboratory, UNESP, Avenue 24 A, Bela Vista-Rio, 13506-900 Rio Claro, SP, Brazil.
authors: Cláudio de Oliveira
authors: Cde O
authors: Assumpção
authors: Leonardo Coelho Rabello
authors: LC
authors: Lima
authors: Felipe Bruno Dias
authors: FB
authors: Oliveira
authors: Camila Coelho
authors: CC
authors: Greco
authors: Benedito Sérgio
authors: BS
authors: Denadai
mesh_terms: D056352:Athletes; D019587:Dietary Supplements; D015444:Exercise / Q000502:physiology*; D006801:Humans; D053580:Muscle Strength / Q000502:physiology; D018482:Muscle, Skeletal / Q000293:injuries* / Q000502:physiology / Q000503:physiopathology*; D009135:Muscular Diseases / Q000209:etiology*; D055070:Resistance Training; D012420:Running / Q000502:physiology*