title: [Assessment of exposure to tobacco smoke in a selected group of patients with multiple sclerosis from the Upper Silesia region].
abstract: In recent years, the increase in the incidence of multiple sclerosis (MS - Multiple Sclerosis) is observed. and the direct cause of the symptoms of multiple sclerosis is myelin nerves damage. It can be concluded that the environmental factor is at least partly responsible for the occurrence of this disease. For the development of this disease are responsible, in addition to genetic factors, compounds present in many parts of the environment. Many of these compounds may adversely affect the redox equilibrium of the body, exacerbating radicalgenesis and decreasing antioxidant defenses. Multiple sclerosis is usually diagnosed in early adulthood, during most daily activities. Effects of SM on living standards includes not only the medical aspect, but also social, economic and emotional aspect. Polish population is a high risk zone regarding multiple sclerosis. The aim of this study was a preliminary assessment of selected environmental exposure factors in the pathogenesis of multiple sclerosis with regard to exposure to tobacco smoke with the author's survey of patients from the region of Upper Silesia. Most MS patients (32) in the study group (suffering from MS from 2 to 44 years) are inhabitants of agglomeration of over 50 thousand citizens, from the area of Gliwice, Bytom and Zabrze (43.75%). In investigated group 46.88% MS patients from Silesia region were exposed to tobacco smoke, of which 21.88% actively smoke. Patients with MS, in order not to worsen their disease manifestation, should stop smoking and increase, if possible, any physical activities. These data will be incorporated into a wide-ranging research to clarify the role of selected environmental factors in a very complex and still not fully explored the pathogenesis of multiple sclerosis in Upper Silesia.
authors: Katedra i Zakład Chemii, Wydział Lekarski z Oddziałem Lekarsko-Dentystycznym w Zabrzu, Slaski Uniwersytet Medyczny.
authors: Cezary
authors: C
authors: Dobosz
authors: Krystyna
authors: K
authors: Tyrpień
authors: Krystyna
authors: K
authors: Pierzchała
mesh_terms: D000293:Adolescent; D000328:Adult; D015984:Causality; D002648:Child; D002675:Child, Preschool; D015897:Comorbidity; D004781:Environmental Exposure / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000453:epidemiology*; D011044:Poland / Q000453:epidemiology; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology; D000074606:Smoking Prevention; D014028:Tobacco Smoke Pollution / Q000706:statistics & numerical data; D055815:Young Adult
chemical_list: D014028:Tobacco Smoke Pollution