title: Diabetes does not affect outcome of symptomatic carotid stenosis treated with endovascular techniques.
abstract: BACKGROUND
  The influence of diabetes on carotid revascularization techniques is controversial, with few data regarding angioplasty and stenting (CAS). Our purpose was to analyze whether its presence constitutes a risk factor for poor outcome of patients with carotid stenosis treated with CAS.
  
  
  METHODS
  We compared 30-day and long term morbidity and mortality, as well as restenosis rates, of non diabetic and diabetic patients with symptomatic carotid stenosis treated with endovascular techniques.
  
  
  RESULTS
  318 consecutive patients, 116 (36.5%) of them diabetics, were followed for a median of 56 months. Cumulative 30-day stroke, ischemic cardiopathy and death rate was 4% for non diabetics and 5.2% for diabetics (non significant). Long term stroke and mortality rate was 26.4% for the first group and 34.3% for the second (non significant). The most frequent causes of death were myocardial infarction (17.5% non diabetics, 44% diabetics, p = 0.04), ischemic stroke (12.5% non diabetics, 4% diabetics, non significant) and cancer (30% non diabetics, 16% diabetics, non significant). Twelve patients (6.4%) had restenosis ≥ 50%, 5.9% non diabetic, 7.4% diabetic, also without statistical significance.
  
  
  CONCLUSIONS
  In our series, endovascular treatment is both efficient and safe in diabetic patients with symptomatic carotid stenosis; therefore, the presence of diabetes mellitus did not increase the risks linked to CAS procedure.
authors: Department of Neurology, Hospital Universitari la Fe, Valencia, Spain. alagom @ meditex.es
authors: Aida
authors: A
authors: Lago
authors: Vera
authors: V
authors: Parkhutik
authors: Jose Ignacio
authors: JI
authors: Tembl
authors: Ara
authors: A
authors: Bermejo
authors: Fernando
authors: F
authors: Aparici
authors: Esperanza
authors: E
authors: Mainar
authors: Víctor
authors: V
authors: Vázquez-Añón
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017130:Angioplasty / Q000009:adverse effects*; D016893:Carotid Stenosis / Q000150:complications / Q000401:mortality / Q000601:surgery; D002423:Cause of Death; D003920:Diabetes Mellitus / Q000401:mortality / Q000503:physiopathology* / Q000601:surgery; D057510:Endovascular Procedures / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology / Q000401:mortality; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D020521:Stroke / Q000209:etiology / Q000401:mortality; D016896:Treatment Outcome