title: Randomized controlled trial of MyLastDip: a Web-based smokeless tobacco cessation program for chewers ages 14-25.
abstract: BACKGROUND
  Use of smokeless tobacco (ST) is a significant public health problem for young adults, many of whom want to quit. We describe the outcome of a Randomized Controlled Trial (RCT) examining the efficacy of two web-based ST cessation interventions targeting young chewers.
  
  
  METHODS
  One thousand seven hundred and sixteen ST users wanting to quit were recruited online to the MyLastDip program and randomly assigned to one of two fully automated web-based ST cessation interventions: (a) an Enhanced Condition (N = 857) with tailored treatment recommendations and interactive features, or (b) a Basic Condition (N = 859) that provided an online ST cessation guide in static text.
  
  
  RESULTS
  Assessment completion rates at 3 months, 6 months, and for both 3 and 6 months were 73%, 71%, and 65%, respectively. No significant differences were found between conditions. Using complete case analysis for repeated point prevalence (3- and 6-month assessments), all tobacco abstinence was 28.9% for participants in the Enhanced Condition and 25.6% in the Basic Condition. Using intent-to-treat analysis, abstinence rates were 35.2% versus 32.3%. Similar results were obtained for ST abstinence. Participants reported being satisfied with their programs and the Enhanced Condition participants were relatively more engaged. Differences in program engagement were not related to tobacco abstinence at 6 months.
  
  
  CONCLUSIONS
  Both web-based ST cessation programs encouraged robust levels of absolute tobacco and ST abstinence at follow-up. The absence of between-group differences was discussed in terms of composition of the control condition and implications for next steps in treatment development and testing.
authors: Oregon Research Institute, Eugene, OR 97403, USA. briand@ori.org
authors: Brian G
authors: BG
authors: Danaher
authors: Herbert H
authors: HH
authors: Severson
authors: Judy A
authors: JA
authors: Andrews
authors: Milagra S
authors: MS
authors: Tyler
authors: Edward
authors: E
authors: Lichtenstein
authors: Timothy G
authors: TG
authors: Woolley
authors: John R
authors: JR
authors: Seeley
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D020407:Internet; D008297:Male; D020340:Tobacco Use Cessation / Q000379:methods*; D055815:Young Adult