title: Dual-energy lung perfusion and ventilation CT in children.
abstract: Dual-energy thoracic CT provides two key insights into lung physiology, i.e. regional perfusion and ventilation, and has been actively investigated to find clinically relevant applications since the introduction of dual-source CT. This functional information provided by dual-energy thoracic CT is supplementary because high-resolution thoracic anatomy is entirely preserved on dual-energy thoracic CT. In addition, virtual non-contrast imaging can omit pre-contrast scanning. In this respect, dual-energy CT imaging technique is at least dose-neutral, which is a critical requirement for paediatric imaging. In this review, imaging protocols, analysis methods, clinical applications and diagnostic pitfalls of dual-energy thoracic CT for evaluating lung perfusion and ventilation in children are described.
authors: Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, South Korea. hwgoo@amc.seoul.kr
authors: Hyun Woo
authors: HW
authors: Goo
mesh_terms: D002648:Child; D006801:Humans; D008171:Lung Diseases / Q000000981:diagnostic imaging*; D055420:Perfusion Imaging / Q000379:methods*; D012123:Pulmonary Ventilation; D015900:Radiography, Dual-Energy Scanned Projection / Q000379:methods*; D013902:Radiography, Thoracic / Q000379:methods*; D012120:Respiration Disorders / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000639:trends*