title: Mullen scales of early learning: the utility in assessing children diagnosed with autism spectrum disorders, cerebral palsy, and epilepsy.
abstract: A group of 47 patients diagnosed with neurodevelopmental disorders were compared to 47 age-, gender-, and racially matched typically developing children to examine the frequency of impairment across domains of the Mullen Scales of Early Learning (MSEL). The MSEL is a comprehensive measure of cognitive functioning designed to assess infants and preschool children between the ages of birth to 68 months. In the neurodevelopmental group, the sample was composed of children 2 to 4 years of age who were diagnosed with autism spectrum disorders (ASD; n = 19), cerebral palsy (CP; n = 14), and epilepsy (EPI; n = 14). A sample of 47 matched controls, taken from the normative sample of the MSEL, was used as a comparison group. Each one of the clinical groups comprising the neurodevelopmental sample demonstrated statistically significant delays across domains relative to the respective matched control group (p < .001). Children failed to demonstrate a "signature" profile for a diagnosis of ASD, CP, or EPI. The clinical sensitivity of the MSEL and the need for obtaining specific intervention services for children diagnosed with these conditions are presented. Finally, these results are discussed within the context of the clinical sensitivity of the MSEL in working with these clinical populations.
authors: Department of Neuropsychology/Neurosciences Division, Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA 30342, USA. Thomas.burns@choa.org
authors: Thomas G
authors: TG
authors: Burns
authors: Tricia Z
authors: TZ
authors: King
authors: Katherine S
authors: KS
authors: Spencer
mesh_terms: D002547:Cerebral Palsy / Q000175:diagnosis* / Q000503:physiopathology; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis* / Q000503:physiopathology; D002675:Child, Preschool; D003072:Cognition Disorders / Q000175:diagnosis* / Q000503:physiopathology; D002658:Developmental Disabilities / Q000175:diagnosis* / Q000503:physiopathology; D004827:Epilepsy / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007858:Learning / Q000502:physiology; D008297:Male; D009483:Neuropsychological Tests / Q000592:standards*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity