title: Catalytic enantioselective epoxidation of tertiary allylic and homoallylic alcohols.
abstract: An efficient and versatile method for the enantioselective epoxidation of both tertiary allylic and homoallylic alcohols catalyzed by Hf(IV)-bishydroxamic acid (BHA) complexes is described. Asymmetric epoxidation, kinetic resolution, and desymmetrization have been developed, demonstrating the flexible nature of the Hf(IV)-BHA system. This is the first report in which these substrates were obtained with enantioselectivities of up to 99%.
authors: Department of Chemistry, The University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, United States.
authors: José Luis
authors: JL
authors: Olivares-Romero
authors: Zhi
authors: Z
authors: Li
authors: Hisashi
authors: H
authors: Yamamoto
mesh_terms: D002384:Catalysis; D004852:Epoxy Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D020005:Propanols / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D004852:Epoxy Compounds; D020005:Propanols; C006463:allyl alcohol