title: Synthesis and NMR studies of novel chromone-2-carboxamide derivatives.
abstract: Chromones are heterocyclic compounds of natural or synthetic origin that possess relevant pharmacological activities. Versatile functionalization of the chromone nucleus allows attaining of a chemical diversity suitable to perform structure-activity relationships in drug discovery and development programs. Accordingly, the synthesis and identification of novel chromone carboxamide derivatives with electron-donating and electron-withdrawing substituents in different positions of the exocyclic ring are reported in this work. Their complete structural characterization was performed using one-dimensional and two-dimensional resonance techniques. The data acquired are useful for a prompt analysis of related compounds that encompass our integrated medicinal chemistry sketch.
authors: Alexandra
authors: A
authors: Gaspar
authors: Fernando
authors: F
authors: Cagide
authors: Elias
authors: E
authors: Quezada
authors: Joana
authors: J
authors: Reis
authors: Eugenio
authors: E
authors: Uriarte
authors: Fernanda
authors: F
authors: Borges
mesh_terms: D002867:Chromones / Q000138:chemical synthesis* / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008872:Microwaves; D015394:Molecular Structure; D012015:Reference Standards
chemical_list: D002867:Chromones; D006571:Heterocyclic Compounds