title: Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): a new approach in liver resections.
abstract: BACKGROUND
  Postoperative liver failure consequent to insufficiency of remnant liver is a feared complication in patients who underwent extensive liver resections. The associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a new approach for patient which tumor is previously considered unresectable.
  
  
  OBJECTIVE
  To present ALPPS as an innovative surgical technique of two-staged hepatectomy for the treatment of patients with marginally resectable or initially nonresectable primary and metastatic liver tumors.
  
  
  METHODS
  The procedure is performed in two steps. The first consists on ligation of the right portal vein branch. Subsequently, total or nearly total parenchyma dissection along the falciform ligament is performed, including the middle hepatic vein. A plastic bag is used to cover the right extended lobe, and the abdomen is drained and closed. The second one is performed after a computer tomography, six to 12 days interval. After laparotomy, the plastic bag is removed. The right artery, right bile duct and the right hepatic vein are divided. The extended right lobe is removed. Drain is placed at the resection surface, and the abdomen is closed.
  
  
  CONCLUSIONS
  The associating of liver partition and portal vein ligation can enable curative resection of liver metastasis in patients with lesions previously considered unresectable.
authors: Department of Digestive Surgery, UDI Hospital, São Luis, MA, Brazil. o.torres@uol.com.br
authors: Orlando Jorge Martins
authors: OJ
authors: Torres
authors: José Maria Assunção
authors: JM
authors: Moraes-Junior
authors: Nádia Caroline
authors: NC
authors: Lima e Lima
authors: Anmara Moura
authors: AM
authors: Moraes
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary / Q000601:surgery*; D000328:Adult; D015179:Colorectal Neoplasms / Q000473:pathology; D005260:Female; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008026:Ligation; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery*; D011169:Portal Vein / Q000601:surgery*