title: The protein corona mediates the impact of nanomaterials and slows amyloid beta fibrillation.
abstract: Put your coat on: It is well recognized that the surfaces of nanomaterials in biological media are covered by various biomolecules (e.g., proteins). A) The protein corona creates a shell over different nanomaterials, regardless of their physicochemical properties (e.g., composition and shape), resulting in reduced levels of amyloid beta fibril formation. B) Pristine nanomaterials might have acceleratory effects on the fibrillation of amyloid beta.
authors: Department of Nanotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Engelab Street, 14155-6451 Tehran, Iran. Mahmoudi@biospion.com
authors: Morteza
authors: M
authors: Mahmoudi
authors: Marco P
authors: MP
authors: Monopoli
authors: Meisam
authors: M
authors: Rezaei
authors: Iseult
authors: I
authors: Lynch
authors: Filippo
authors: F
authors: Bertoli
authors: Jennifer J
authors: JJ
authors: McManus
authors: Kenneth A
authors: KA
authors: Dawson
mesh_terms: D016229:Amyloid beta-Peptides / Q000737:chemistry / Q000378:metabolism*; D037741:Fullerenes / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D037742:Nanotubes, Carbon / Q000737:chemistry; D011137:Polystyrenes / Q000737:chemistry
chemical_list: D016229:Amyloid beta-Peptides; D037741:Fullerenes; D037742:Nanotubes, Carbon; D011137:Polystyrenes; C530172:pristine (C60)