title: Effect of glycine powder air-polishing as an adjunct in the treatment of peri-implant mucositis: a pilot clinical trial.
abstract: BACKGROUND
  Glycine powder air-polishing (GPAP) has the potential to effectively erase biofilms and may improve the treatment efficacy of peri-implant mucositis. This pilot clinical trial evaluated the effect of GPAP as an adjunct in treating peri-implant mucositis.
  
  
  METHODS
  Twenty-four subjects having at least one implant with peri-implant mucositis were randomly assigned to test (12 subjects with 17 implants) and control (12 subjects with 16 implants) groups. Following baseline assessment, all subjects received oral hygiene instruction and non-surgical debridement. In the test group, the sites with probing depth (PD) ≥4 mm were additionally treated by GPAP for 5 sec. Clinical parameters were measured at 1-week, 1-month, and 3-month recall visits.
  
  
  RESULTS
  At the 3-month visit, the mean reductions in PD at site level were 0.93 ± 0.93 mm and 0.91 ± 0.98 mm in the test and control groups, respectively (P < 0.05), and no significant difference existed between two groups. Mean bleeding score was also significantly reduced in both groups after the intervention. No complications or discomfort were reported during the study.
  
  
  CONCLUSIONS
  This pilot clinical trial suggests that non-surgical mechanical debridement may effectively control peri-implant mucositis, and adjunctive GPAP treatment seems to have a limited beneficial effect as compared with mechanical debridement alone. However, further clinical trials with a large sample size are needed to confirm this preliminary observation.
authors: The Second Dental Center, Peking University School and Hospital of Stomatology, Beijing, China.
authors: Ying-Jie
authors: YJ
authors: Ji
authors: Zhi-Hui
authors: ZH
authors: Tang
authors: Ren
authors: R
authors: Wang
authors: Jie
authors: J
authors: Cao
authors: Cai-Fang
authors: CF
authors: Cao
authors: Li-Jian
authors: LJ
authors: Jin
mesh_terms: D000328:Adult; D020906:Air Abrasion, Dental; D018441:Biofilms; D002681:China; D003646:Debridement; D005260:Female; D005998:Glycine / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D057873:Peri-Implantitis / Q000628:therapy*; D010512:Periodontal Index; D010865:Pilot Projects; D011208:Powders; D015203:Reproducibility of Results; D016037:Single-Blind Method; D016896:Treatment Outcome
chemical_list: D011208:Powders; D005998:Glycine
keywords: air-polishing; mechanical debridement; peri-implant mucositis