title: Incision integrity and postoperative outcomes after microcoaxial phacoemulsification performed using 2 incision-dependent systems.
abstract: OBJECTIVE
  To compare incision integrity and clinical outcomes of 2 microcoaxial phacoemulsification systems.
  
  
  METHODS
  Iladevi Cataract & IOL Research Centre, Ahmedabad, India.
  
  
  METHODS
  Prospective randomized clinical trial.
  
  
  METHODS
  Eyes were randomized to have phacoemulsification using a 1.8 mm clear corneal incision (CCI) system (Group 1, Stellaris system) or a 2.2 mm CCI system (Group 2, Intrepid Infiniti system). Incision enlargement at end of surgery was measured. At the conclusion of surgery, trypan blue was applied over the conjunctival surface, anterior chamber aspirate withdrawn, and ingress into anterior chamber measured. Postoperative observations included evaluation of the CCI using anterior segment optical coherence tomography (AS-OCT), change in central corneal thickness (CCT), and anterior segment inflammation at 1 day, 1 week, and 1 month and endothelial cell loss and surgically induced astigmatism (SIA) at 3 months.
  
  
  RESULTS
  Incision enlargement (P<.001) and trypan blue ingress in the anterior chamber (mean 1.7 log units ± 0.6 [SD] versus 3.8 ± 0.6 log units, P<.001) was significantly greater in Group 1 (n = 50) than in Group 2 (n = 50). On AS-OCT, endothelial misalignment and gaping were more frequent in Group 1 at 1 day (P=.001) and 1 week (P=.018). There were no significant differences in SIA, change in CCT, endothelial cell loss, or anterior segment inflammation (P>.05).
  
  
  CONCLUSIONS
  At the end of surgery, it is not the initial incision size alone but also the distortion of the incision during subsequent stages of surgery that determine the integrity of the CCI.
authors: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.
authors: Vaishali
authors: V
authors: Vasavada
authors: Abhay R
authors: AR
authors: Vasavada
authors: Viraj A
authors: VA
authors: Vasavada
authors: Samaresh
authors: S
authors: Srivastava
authors: Devarshi U
authors: DU
authors: Gajjar
authors: Siddharth
authors: S
authors: Mehta
mesh_terms: D001082:Aqueous Humor / Q000378:metabolism; D004396:Coloring Agents / Q000378:metabolism; D003315:Cornea / Q000473:pathology / Q000601:surgery*; D055954:Corneal Endothelial Cell Loss / Q000175:diagnosis; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007431:Intraoperative Complications; D019654:Lens Implantation, Intraocular; D008297:Male; D008866:Microsurgery / Q000379:methods*; D008875:Middle Aged; D018918:Phacoemulsification / Q000379:methods*; D011183:Postoperative Complications; D011446:Prospective Studies; D013529:Surgical Wound Dehiscence / Q000378:metabolism / Q000503:physiopathology*; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014343:Trypan Blue / Q000378:metabolism; D014945:Wound Healing / Q000502:physiology
chemical_list: D004396:Coloring Agents; D014343:Trypan Blue