title: The use of molecularly imprinted polymers for the multicomponent determination of endocrine-disrupting compounds in water and sediment.
abstract: The method employing molecularly imprinted polymers for the extraction and clean up of endocrine-disrupting compounds (estrogens, bisphenol A, and alkylphenols) from water and sediment is described. The identical extraction/clean-up and LC-MS/MS condition were used for the analysis of both types of samples. The method showed high recoveries ranging from 90 to 99% with excellent precision (intrabatch: 3.6-9.3%; interbatch: 5.6-11.4% for water; intrabatch: 4.3-8.5%; interbatch: 6.1-9.6% for sediment). The LOD was in the range of 0.7-1.9 ng/L and 0.3-0.6 ng/g for water and sediment, respectively. Overall extraction on molecularly imprinted polymers substantially enhanced sample clean-up. The difference in efficiency of clean-up was particularly pronounced when a large sample volume/weight was extracted and analyzed. Finally, the method was successfully applied for the analysis of 20 water and sediment samples.
authors: Department of Chemistry and Biochemistry, Mendel University in Brno, Brno, Czech Republic. matejicekdavid@seznam.cz
authors: David
authors: D
authors: Matějíček
authors: Alena
authors: A
authors: Grycová
authors: Jiří
authors: J
authors: Vlček
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D052244:Endocrine Disruptors / Q000032:analysis / Q000302:isolation & purification*; D019015:Geologic Sediments / Q000032:analysis*; D054802:Molecular Imprinting; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D053719:Tandem Mass Spectrometry / Q000379:methods; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000302:isolation & purification*
chemical_list: D052244:Endocrine Disruptors; D011108:Polymers; D014874:Water Pollutants, Chemical