title: Difference in distribution of Chlamydia trachomatis genotypes among different provinces: a pilot study from four provinces in China.
abstract: The objective of this study was to assess the distribution of Chlamydia trachomatis genovars in male sexually transmitted disease (STD) clinic patients from 1 province in eastern China (Jiangsu) and 3 provinces in southern China (Guangdong, Guangxi, and Hainan). Urine specimens (n = 140) were collected from 46 public STD clinics in the 4 provinces. Specimens that tested positive for C. trachomatis by polymerase chain reaction were genotyped for the infecting C. trachomatis strain by amplifying and sequencing the genovar-specific ompA gene, which encodes the chlamydial major outer-membrane protein. Nine C. trachomatis genovars were identified from 129 specimens; they consisted of the F (25.6%), E (17.1%), J (16.3%), D (15.5%), G (11.6%), K (5.4%), H (3.9%), I (1.6%), and B (0.8%) genovars. Nine genovars were found in specimens from Guangxi province, 6 were found in specimens from each of Guangdong and Hainan provinces, but only 5 were found in specimens from Jiangsu province. Genovar G/Ga was shown to be endemic among male patients in southern China.
authors: National Center for STD Control & Chinese Academy of Medical Sciences & Peking Union Medical College Institute of Dermatology, Nanjing, China.
authors: Yan
authors: Y
authors: Han
authors: Yue-ping
authors: YP
authors: Yin
authors: Mei-qin
authors: MQ
authors: Shi
authors: Ming-ying
authors: MY
authors: Zhong
authors: Shao-chun
authors: SC
authors: Chen
authors: Zhi
authors: Z
authors: Xang
authors: Ning
authors: N
authors: Jiang
authors: Xiang-sheng
authors: XS
authors: Chen
mesh_terms: D000328:Adult; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D002681:China / Q000453:epidemiology; D002690:Chlamydia Infections / Q000453:epidemiology / Q000382:microbiology*; D002692:Chlamydia trachomatis / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics / Q000652:urine; D005838:Genotype; D005843:Geography; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D013045:Species Specificity
chemical_list: D001425:Bacterial Outer Membrane Proteins; D004269:DNA, Bacterial; C078167:OMPA outer membrane proteins