title: The correlation between retinal blood flow velocity measured by the retinal function imager and various physiological parameters.
abstract: OBJECTIVE
  The retinal function imager (RFI) (Optical Imaging Ltd., Rehovot, Israel) measures retinal blood flow velocity non-invasively. The authors studied the reproducibility of these measurements and assessed the effect of physiological components on them.
  
  
  METHODS
  Sixty-seven individuals with no retinal pathology were recruited. Velocity reproducibility was verified by comparing repeated RFI measurements. The correlation of the velocity with physiological parameters was assessed by mixed linear and Gaussian models.
  
  
  RESULTS
  The average velocity was 4.2 ± 0.9 mm/sec arterial and 3.3 ± 0.8 mm/sec venous. Variability was 7.5% ± 3.7% and interclass correlation coefficient was r = 0.744. Venous velocity decreased after 40 years of age (0.32 mm/sec per decade, P < .01). Arterial velocity increased as mean arterial pressure increased (0.25 mm/sec per 10 mm Hg, P < .01). There was also a positive association between velocities and heart rate (arteries: 0.21 mm/sec per 10 bpm, P < .05; veins: 0.22 mm/sec per 10 bpm, P < .01).
  
  
  CONCLUSIONS
  The RFI provides a reproducible, non-invasive technique to assess retinal velocities.
authors: Department of Ophthalmology, The Edith Wolfson Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Holon, Israel.
authors: Zvia
authors: Z
authors: Burgansky-Eliash
authors: Anat
authors: A
authors: Lowenstein
authors: Meira
authors: M
authors: Neuderfer
authors: Anat
authors: A
authors: Kesler
authors: Hila
authors: H
authors: Barash
authors: Darin A
authors: DA
authors: Nelson
authors: Amiram
authors: A
authors: Grinvald
authors: Adiel
authors: A
authors: Barak
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D062186:Arterial Pressure; D001783:Blood Flow Velocity / Q000502:physiology*; D003941:Diagnostic Techniques, Ophthalmological / Q000295:instrumentation*; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012161:Retinal Artery / Q000502:physiology*; D012169:Retinal Vein / Q000502:physiology*; D055815:Young Adult