title: Single nucleotide polymorphisms rs2120131, rs4935047, and rs7095891 in the MBL2 gene show no association with susceptibility to chronic hepatitis B in a Chinese Han population.
abstract: Thus far, many studies have evaluated the correlation between MBL2 gene polymorphisms and hepatitis B infection. Tag single nucleotide polymorphisms (SNPs) were used to investigate the relationship between MBL2 gene polymorphisms and susceptibility to chronic hepatitis B virus (HBV) infection by comparing 996 chronic HBV infection cases to 301 acute infection controls. There was no significant correlation between rs2120131, rs4935047, and rs7095891 and chronic HBV infection. This suggested that the new SNPs within MBL2 were not associated with susceptibility to chronic hepatitis B in a Chinese Han population.
authors: Jiangxi Center for Disease Control and Prevention, 555 Beijing East Road, Nanchang, Jiangxi 330000, China.
authors: Tian-Chen
authors: TC
authors: Zhang
authors: Wei
authors: W
authors: Liu
authors: Xiao-Qing
authors: XQ
authors: Liu
authors: Fa-Ming
authors: FM
authors: Pan
authors: Yu-Feng
authors: YF
authors: Gao
authors: Fang
authors: F
authors: Yan
authors: Xu
authors: X
authors: Li
mesh_terms: D000328:Adult; D002681:China; D005260:Female; D020022:Genetic Predisposition to Disease; D019694:Hepatitis B, Chronic / Q000235:genetics*; D006801:Humans; D008297:Male; D037601:Mannose-Binding Lectin / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide
chemical_list: C445619:MBL2 protein, human; D037601:Mannose-Binding Lectin