title: Chemical constituents from the aerial parts of Gynura bicolor.
abstract: Gynura bicolor (Willd.) DC., is used in folk recipes for the treatment of diabetes mellitus in Jiangsu, Zhejiang and Sichuan province in the south of China. A previous pharmacological study proved that the plant showed significant hypoglycemic activity on normal and alloxan-diabetic mice. In this study, two terpenes, four megastigmane-type norisoprenoids and two glycosides were isolated from the aqueous ethanolic extract of the aerial parts of Gynura bicolor and characterized mainly by NMR spectroscopy and mass spectrometry. Thes e compounds were isolated for the first time from this plant, and no evidence could be found for the previous reported presence of megastigmane-type norisoprenoids in the genus Gynura.
authors: Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210009, China.
authors: Jian
authors: J
authors: Chen
authors: Sven
authors: S
authors: Mangelinckx
authors: An
authors: A
authors: Adams
authors: Wei-Lin
authors: WL
authors: Li
authors: Zheng-Tao
authors: ZT
authors: Wang
authors: Norbert
authors: N
authors: De Kimpe
mesh_terms: D019659:Asteraceae / Q000737:chemistry* / Q000145:classification; D002851:Chromatography, High Pressure Liquid; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification; D007202:Indicators and Reagents; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010936:Plant Extracts / Q000737:chemistry; D012997:Solvents; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification
chemical_list: D006027:Glycosides; D007202:Indicators and Reagents; D010936:Plant Extracts; D012997:Solvents; D013729:Terpenes