title: Eight and a half syndrome with hemiparesis and hemihypesthesia: the nine syndrome?
abstract: "Eight-and-a-half" syndrome is "one-and-a-half" syndrome (conjugated horizontal gaze palsy and internuclear ophthalmoplegia) plus ipsilateral fascicular cranial nerve seventh palsy. This rare condition, particularly when isolated, is caused by circumscribed lesions of the pontine tegmentum involving the abducens nucleus, the ipsilateral medial longitudinal fasciculus, and the adjacent facial colliculus. Its recognition is therefore of considerable diagnostic value. We report a 71-year-old man who presented with eight and a half syndrome associated with contralateral hemiparesis and hemihypesthesia, in which brain magnetic resonance imaging scans revealed a lacunar pontine infarction also involving the corticospinal tract and medial lemniscus. These features could widen the spectrum of pontine infarctions, configuring a possible "nine" syndrome.
authors: Eye Tracking & Visual Application Lab, Department of Neurological, Neurosurgical, and Behavioral Sciences, Siena, Italy.
authors: Francesca
authors: F
authors: Rosini
authors: Elena
authors: E
authors: Pretegiani
authors: Francesca
authors: F
authors: Guideri
authors: Alfonso
authors: A
authors: Cerase
authors: Alessandra
authors: A
authors: Rufa
mesh_terms: D000368:Aged; D038524:Diffusion Magnetic Resonance Imaging; D005155:Facial Nerve Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D005158:Facial Paralysis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D006987:Hypesthesia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008297:Male; D015835:Ocular Motility Disorders / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D010291:Paresis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D026741:Physical Therapy Modalities; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011149:Pons / Q000098:blood supply*; D011237:Predictive Value of Tests; D059409:Stroke, Lacunar / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D013577:Syndrome; D009626:Terminology as Topic; D016896:Treatment Outcome
chemical_list: D010975:Platelet Aggregation Inhibitors
keywords: Acute pontine stroke; neuro-ophthalmology; neuroimaging