title: Boston type 1 keratoprosthesis outcomes in ocular burns.
abstract: OBJECTIVE
  To report the outcomes of Boston type I keratoprosthesis (BKPro) in the management of ocular burn injuries.
  
  
  METHODS
  This was a prospective study including all cases of BKPro implantation for ocular burns at the External Diseases and Cornea Service of the Federal University of São Paulo, between February 2008 and February 2010. Ten patients (10 eyes) were enrolled. Procedures performed to manage ocular injury were identified, and data were collected regarding patients' ocular history, surgical procedure(s) performed, and postoperative outcomes, including visual acuity, retention, complications and required surgical procedures.
  
  
  RESULTS
  A total of 11 Type 1 BKPro were implanted in 10 eyes of 10 patients. The mean follow-up period was 25.7 ± 10.8 months. Preoperative best-corrected visual acuity (BCVA) ranged from count fingers to light perception. Postoperative BCVA was better than 20/200 in 90% of the patients and better than 20/60 in 60% of the patients. The overall BKPro retention rate was 90%. The most common complications were retroprosthetic membrane formation (50%) and persistent corneal epithelial defect evolving to corneal melting (40%). Patients who underwent ocular surface procedures such as limbal transplantation prior to BKPRo implantation had a lower incidence of corneal melting/thinning (p = 0.07), although this was not statistically significant.
  
  
  CONCLUSIONS
  The anatomical and functional results identified in this study support the use of BKPro in managing bilateral limbal stem cell deficiency secondary to ocular burns.
authors: Department of Ophthalmology, Federal University of São Paulo, Brazil. fernandapedreiramagalhaes@yahoo.com.br
authors: Fernanda Pedreira
authors: FP
authors: Magalhães
authors: Flavio Eduardo
authors: FE
authors: Hirai
authors: Luciene Barbosa
authors: LB
authors: de Sousa
authors: Lauro Augusto
authors: LA
authors: de Oliveira
mesh_terms: D000328:Adult; D000468:Alkalies; D001187:Artificial Organs; D001705:Bioprosthesis; D002057:Burns, Chemical / Q000601:surgery*; D003316:Corneal Diseases / Q000139:chemically induced / Q000601:surgery*; D005126:Eye Burns / Q000139:chemically induced* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies; D019919:Prosthesis Implantation; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000468:Alkalies
keywords: chemical burn; keratoprosthesis; ocular injury