title: Relationships between psychopathological variables and insight in psychosis risk syndrome and first-episode and multiepisode schizophrenia.
abstract: Insight may vary across psychosis risk syndrome (PRS), first-episode schizophrenia (FES), or multiepisode schizophrenia (MES). We aimed to compare insight domains (awareness, relabeling, and compliance) in PRS, FES, and MES groups and to correlate scores with psychopathological measures. Insight was assessed in 48 (14 PRS, 16 FES, and 18 MES) patients using the Schedule for the Assessment of Insight-Expanded Version. We conducted psychopathological assessment through the Brief Psychiatric Rating Scale (BPRS). In the whole group, the BPRS psychosis factor correlated with all insight domains. In the MES group, the more severe the anxiety/depression, the higher the insight score in the symptom relabeling domain. Insight did not differ significantly between the PRS, FES, and MES groups. Our results suggest that, across different phases of the illness, lack of insight behaves like a trait and is modulated by positive symptom severity. Anxiety and depression may be associated with increased insight in patients with chronic schizophrenia.
authors: Unit of Psychiatry, Sapienza University of Rome, School of Medicine and Psychology, NESMOS Department (Neurosciences, Mental Health and Sense Organs), Sant'Andrea Hospital, Rome, Italy. anna.comparelli@uniroma1.it
authors: Anna
authors: A
authors: Comparelli
authors: Valeria
authors: V
authors: Savoja
authors: Antonella
authors: A
authors: De Carolis
authors: Simone
authors: S
authors: Di Pietro
authors: Georgios D
authors: GD
authors: Kotzalidis
authors: Valentina
authors: V
authors: Corigliano
authors: Ilaria
authors: I
authors: Falcone
authors: Roberto
authors: R
authors: Tatarelli
authors: Stefano
authors: S
authors: Ferracuti
authors: Paolo
authors: P
authors: Girardi
mesh_terms: D000328:Adult; D001364:Awareness / Q000502:physiology; D010054:Brief Psychiatric Rating Scale; D005260:Female; D006801:Humans; D007297:Inpatients / Q000523:psychology; D008297:Male; D010045:Outpatients / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000145:classification / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D013577:Syndrome