title: The surgical management of necrotizing enterocolitis.
abstract: Necrotizing enterocolitis (NEC), a common cause of neonatal morbidity and mortality, is strongly associated with prematurity and typically occurs following initiation of enteral feeds. Mild NEC is adequately treated by cessation of enteral feeding, empiric antibiotics, and supportive care. Approximately 50% of affected infants will develop progressive intestinal necrosis requiring urgent operation. Several surgical techniques have been described, but there is no clear survival benefit for any single operative approach. While debate continues regarding the optimal surgical management for infants with severe NEC, future progress will likely depend on the development of improved diagnostic tools and preventive therapies.
authors: Stanford Department of Surgery, Lucile Packard Children's Hospital, Stanford University School of Medicine, 300 Pasteur Drive, H3680D, Stanford, CA 94305-5641, USA.
authors: Zachary J
authors: ZJ
authors: Kastenberg
authors: Karl G
authors: KG
authors: Sylvester
mesh_terms: D013505:Digestive System Surgical Procedures / Q000379:methods*; D020345:Enterocolitis, Necrotizing / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000601:surgery*; D007422:Intestines / Q000601:surgery*; D011027:Pneumoperitoneum / Q000000981:diagnostic imaging; D011183:Postoperative Complications; D011859:Radiography