title: Depression and social anxiety in help-seeking patients with an ultra-high risk for developing psychosis.
abstract: Knowledge on associations between ultra-high risk (UHR) for developing psychosis and on non-psychotic psychopathology in help-seeking populations is limited with respect to differences between male and female patients. The present study tests the hypothesis that both social anxiety and depression are highly prevalent in an UHR population, particularly among women. From February 2008 to February 2010 baseline data were collected from help-seeking subjects (14-35 years) who were included in the Dutch Early Detection and Intervention Evaluation (EDIE-NL) trial. Two recruiting strategies were used: a two-stage screening strategy in a population of consecutive help-seeking and distressed subjects of secondary mental health services, and a referral strategy. This study included 201 patients with a mean age of 22.7 years. Of these, 102 (51%) were female, 58% of the patients met the criteria for clinical depression on the Beck Depression Inventory and 42% met the criteria for clinical social phobia on the Social Interaction Anxiety Scale. Women showed more depression and social anxiety than men. The results support the hypothesis that UHR is associated with depression and social anxiety, particularly in women. Screening a help-seeking population with depression and anxiety may be effective in detecting patients at UHR for developing psychosis.
authors: VU University Amsterdam and EMGO(+) Institute of Health and Care Research, Department of Clinical Psychology, Amsterdam, The Netherlands; Parnassia Psychiatric Institute, Department of Psychosis Research, The Hague, The Netherlands. Electronic address: judithrietdijk@gmail.com.
authors: Judith
authors: J
authors: Rietdijk
authors: Helga K
authors: HK
authors: Ising
authors: Sara
authors: S
authors: Dragt
authors: Rianne
authors: R
authors: Klaassen
authors: Dorien
authors: D
authors: Nieman
authors: Lex
authors: L
authors: Wunderink
authors: Pim
authors: P
authors: Cuijpers
authors: Don
authors: D
authors: Linszen
authors: Mark
authors: M
authors: van der Gaag
mesh_terms: D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000523:psychology*; D003863:Depression / Q000523:psychology*; D005260:Female; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D015999:Multivariate Analysis; D010342:Patient Acceptance of Health Care; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000175:diagnosis / Q000209:etiology* / Q000523:psychology*; D012189:Retrospective Studies; D012306:Risk; D012307:Risk Factors; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: Early detection; Psychosis; Ultra-high risk for psychosis