title: Highly efficient Cu(I)-catalyzed oxidation of alcohols to ketones and aldehydes with diaziridinone.
abstract: A novel and efficient Cu(I)-catalyzed oxidation of alcohols has been achieved with di-tert-butyldiaziridinone as the oxidant under mild conditions. A wide variety of primary and secondary alcohols with various functional groups can be oxidized to aldehydes and ketones in high yields. The reaction proceeds under neutral conditions making it compatible with acid- or base-sensitive substrates, and it is amenable to gram scale.
authors: Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA.
authors: Yingguang
authors: Y
authors: Zhu
authors: Baoguo
authors: B
authors: Zhao
authors: Yian
authors: Y
authors: Shi
mesh_terms: D000438:Alcohols / Q000737:chemistry*; D000447:Aldehydes / Q000138:chemical synthesis* / Q000737:chemistry; D001388:Aziridines / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003300:Copper / Q000737:chemistry*; D007454:Iodides / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D000438:Alcohols; D000447:Aldehydes; D001388:Aziridines; D007454:Iodides; D007659:Ketones; D003300:Copper; C073870:cuprous iodide