title: Kidneys from donors with incidental renal tumors: should they be considered acceptable option for transplantation?
abstract: BACKGROUND
  The increase in the prevalence of end-stage renal disease in developed countries and the shortage of deceased donors has made it necessary to increase the graft pool by means of several strategies, such as live donation, non-heart-beating donors, and expanded criteria donors. Frequently, and because of the increasing acceptance of older donors, we find a higher percentage of incidental renal masses in these donors as a result of the inherent epidemiology of this disease. These kidneys can be considered suitable grafts after bench surgery to remove the tumor.
  
  
  METHODS
  Retrospective analysis of donors with a diagnosis of incidental small renal mass before implantation and their corresponding recipients was performed between January 2007 and September 2012. All cases underwent an ex vivo tumorectomy with a preoperatory pathologic analysis. Recipients were followed up according to our standard renal tumor protocol.
  
  
  RESULTS
  Eight donors with incidental renal mass were detected (four live and four deceased donors). The mean age was 47.8 years. Eleven transplantations were performed. Eight cases received the kidney after tumor exeresis, and three, the contralateral one. The recipient mean age was 53.8 years.The mean tumor diameter was 14.8 mm, with pathologic stages pT1a in seven cases and pT1b in one case (five clear cell renal carcinoma, two chromophobe type, and one lipoma). Surgical margins were negative. Mean follow-up was 32.34 months; none of the patients presented tumor recurrence, and all had correct renal function.
  
  
  CONCLUSIONS
  Kidneys with small incidental tumors can be considered an option for kidney transplantation in selected patients.
authors: Department of Urology, University of Barcelona Hospital Clinic, 08036 Barcelona, Spain. mmusquer@clinic.ub.es
authors: Mireia
authors: M
authors: Musquera
authors: Meritxell
authors: M
authors: Pérez
authors: Lluis
authors: L
authors: Peri
authors: Núria
authors: N
authors: Esforzado
authors: Maria Carme
authors: MC
authors: Sebastià
authors: David
authors: D
authors: Paredes
authors: María José
authors: MJ
authors: Ribal
authors: Federico
authors: F
authors: Oppenheimer
authors: Josep Maria
authors: JM
authors: Campistol
authors: Antonio
authors: A
authors: Alcaraz
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D033162:Incidental Findings; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D014019:Tissue Donors