title: Bilateral Ovarian Fibrothecoma Associated with Ascites, Bilateral Pleural Effusion, and Marked Elevated Serum CA-125.
abstract: Background. The risk of ovarian cancer is increased in the association of ovarian tumor, ascites, and hydrothorax with the significant elevated tumor marker CA-125. However, this association can be observed in a rare clinical and benign pathological entity, that is Demons-Meigs' syndrome. Objective. To describe a rare case of Demons-Meigs' syndrome observed in our department. Methods. A black African woman of 35 years old, seventh gravida and fourth parous, underwent a total abdominal hysterectomy with bilateral salpingoophorectomy for large bilateral ovarian masses associated with significant ascites, bilateral pleural effusion, and particular highly elevated tumor marker CA-125 (1835 UI/mL) in a pronounced general alteration condition. Results. The postoperative course was uneventful characterized by a complete remission of hydrothorax and ascites with normal level of CA-125 three months after tumor excision. Histology of both masses revealed a bilateral ovarian fibrothecoma, a benign tumor of the ovary, thus confirming the diagnosis of Demons-Meigs' syndrome. Conclusion. The Demons-Meigs syndrome, although it strongly mimics the clinical picture of malignant metastatic ovarian cancer, remains a disease with benign prognosis after surgical tumor resection. This is a rare condition that must be known and recognized by practitioners to avoid unnecessary practices.
authors: Department of Gynecology and Obstetrics, University Hospital of Cocody, 01 BP V13 Abidjan, Cote D'Ivoire ; Faculty of Medicine, Félix Houphouët Boigny University of Cocody, 01 BP V 13 Abidjan, Cote D'Ivoire.
authors: Védi André Serges
authors: VA
authors: Loué
authors: Eléonore
authors: E
authors: Gbary
authors: Sylvanus
authors: S
authors: Koui
authors: Bédi
authors: B
authors: Akpa
authors: Adélaide
authors: A
authors: Kouassi