title: MAVS: a new weapon in the fight against viral infections.
abstract: In addition to their participation in metabolic processes and control of programmed cell death, the role of mitochondria as a fundamental hub for innate anti-viral immunity is now emerging. The participation of the mitochondrial antiviral signaling protein (MAVS) as a central regulator of a complex signaling cascade, which results in the induction of antiviral and inflammatory responses has been described. A patent based on this role of MAVS is highlighted in this review.
authors: Servicio de Microbiologia, Hospital Universitario Central de Asturias, 33006 Oviedo, Spain. joseantonio.boga@sespa.princast.es
authors: Jose A
authors: JA
authors: Boga
authors: Maria
authors: M
authors: de Oña
authors: Santiago
authors: S
authors: Melon
authors: Marta E
authors: ME
authors: Alvarez-Arguelles
authors: Ana
authors: A
authors: Morilla
authors: Ana
authors: A
authors: Coto-Montes
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000378:metabolism*; D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D015195:Drug Design; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects; D008928:Mitochondria / Q000187:drug effects* / Q000276:immunology / Q000378:metabolism / Q000821:virology; D010330:Patents as Topic; D015398:Signal Transduction / Q000187:drug effects; D014777:Virus Diseases / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism / Q000821:virology
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D000998:Antiviral Agents; C505371:MAVS protein, human