title: [The HPV infection as an alternative to tobacco smoking way of head and neck tumors development--what are the implications for patients?].
abstract: It was established, that HPV virus (Human Papilloma Virus) is responsible for tumor induction in some anatomical regions of head and neck, mainly in palatine tonsils. The characteristics of HPV-related tumors as well as the course of the disease are definitely different compared to tobacco-smoking related tumors; patients HPV-positve have better prognosis - less patients develops recurrences and dies from the disease. There is no full compliance about patients' characteristics, although most indications concern "young adults" with their intensive sexual life. Because the course of HPV-related tumors is milder, there is a need to distinguish the cause of disease to carry on the therapy adjusted to the causative factor. This approach might help to select HPV-negative patients with severe course of disease to apply more aggressive chemotherapy.
authors: Instytut Genetyki Człowieka PAN w Poznaniu. kassz@man.poznan.pl
authors: Katarzyna
authors: K
authors: Kiwerska
authors: Daniela
authors: D
authors: Mielcarek-Kuchta
authors: Małgorzata
authors: M
authors: Jarmuz-Szymczak
authors: Krzysztof
authors: K
authors: Szyfter
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D015984:Causality; D002453:Cell Cycle; D015897:Comorbidity; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology / Q000517:prevention & control; D030361:Papillomavirus Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000473:pathology; D011379:Prognosis; D012307:Risk Factors; D012725:Sexual Behavior; D012907:Smoking / Q000453:epidemiology*; D014412:Tumor Virus Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000473:pathology; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents