title: Chemical compositions, antioxidant and antimicrobial activity of the essential oils of Piper officinarum (Piperaceae).
abstract: This study was designed to investigate the antioxidant and antimicrobial activities of the essential oils from Piper officinarum C. DC. GC and GC/MS analysis of the leaf and stem oils showed forty one components, representing 85.6% and 93.0% of the oil, respectively. The most abundant components in the leaf oil were beta-caryophyllene (11.2%), alpha-pinene (9.3%), sabinene (7.6%), beta-selinene (5.3%) and limonene (4.6%), while beta-caryophyllene (10.9%), alpha-phellandrene (9.3%), linalool (6.9%), limonene (6.7%) and alpha-pinene (5.0%) were the main components of the stem oil. The antioxidant activities were determined by using complementary tests: namely beta-carotene-linoleic acid, DPPH radical scavenging and total phenolic assays. The stems oil showed weak activity (IC50 = 777.4 microg/mL) in the DPPH system, but showed moderate lipid peroxidation inhibition in the beta-carotene-linoleic acid system (88.9 +/- 0.35%) compared with BHT (95.5 +/- 0.30%). Both oils showed weak activity against P. aeruginosa and E. coli with M IC values of 250 microg/mL.
authors: Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, Skudai, 81310 Johor Bahru, Johor, Malaysia.
authors: Wan Mohd Nuzul Hakimi Wan
authors: WM
authors: Salleh
authors: Farediah
authors: F
authors: Ahmad
authors: Khong Heng
authors: KH
authors: Yen
authors: Hasnah Mohd
authors: HM
authors: Sirat
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D001713:Biphenyl Compounds / Q000737:chemistry; D004926:Escherichia coli / Q000187:drug effects; D016166:Free Radical Scavengers / Q000737:chemistry; D005658:Fungi / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D007202:Indicators and Reagents; D019787:Linoleic Acid / Q000737:chemistry; D015227:Lipid Peroxidation / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology*; D010636:Phenols / Q000737:chemistry; D010851:Picrates / Q000737:chemistry; D031701:Piper / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D012997:Solvents; D019207:beta Carotene / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents; D000975:Antioxidants; D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D007202:Indicators and Reagents; D009822:Oils, Volatile; D010636:Phenols; D010851:Picrates; D012997:Solvents; D019207:beta Carotene; D019787:Linoleic Acid; C004931:1,1-diphenyl-2-picrylhydrazyl