title: Factors affecting Brucella spp. blood cultures positivity in children.
abstract: Brucella infections have a wide spectrum of symptoms especially in children, making the diagnosis a complicated process. The gold standard for the final diagnosis for brucellosis is to identify the Brucella spp. isolated from blood or bone marrow cultures. The main purpose of this work was to evaluate the factors affecting the isolation of Brucella spp. from blood cultures. In our study, the ratio of fever, presence of hepatomegaly, and splenomegaly were found to be higher in the bacteremic group. In addition, C-reactive protein levels and liver function enzymes were found to be higher in the bacteremic group. In our opinion, while evaluating the febrile child with suspected Brucella infection, we highly recommend sampling blood cultures regardless of the history of previous antimicrobial therapy and duration of the symptoms.
authors: Department of Infectious Diseases, Uz Children's Training and Research Hospital, Izmir, Turkey.
authors: Hurşit
authors: H
authors: Apa
authors: Ilker
authors: I
authors: Devrim
authors: Seyma
authors: S
authors: Memur
authors: Ilker
authors: I
authors: Günay
authors: Gamze
authors: G
authors: Gülfidan
authors: Mehmet
authors: M
authors: Celegen
authors: Nuri
authors: N
authors: Bayram
authors: Utku
authors: U
authors: Karaarslan
authors: Ozlem
authors: O
authors: Bağ
authors: Rana
authors: R
authors: Işgüder
authors: Aysel
authors: A
authors: Oztürk
authors: Seyhan
authors: S
authors: Inan
authors: Nurrettin
authors: N
authors: Unal
mesh_terms: D000293:Adolescent; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D016470:Bacteremia / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D001800:Blood Specimen Collection; D001853:Bone Marrow / Q000382:microbiology; D002002:Brucella / Q000302:isolation & purification*; D002006:Brucellosis / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology; D002097:C-Reactive Protein / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005334:Fever; D006454:Hemoglobins / Q000032:analysis; D006529:Hepatomegaly; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D013163:Splenomegaly; D014421:Turkey / Q000453:epidemiology
chemical_list: D006454:Hemoglobins; D002097:C-Reactive Protein; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase