title: Correlation between Endoscopic and Histological Diagnoses of Gastric Intestinal Metaplasia.
abstract: OBJECTIVE
  Intestinal metaplasia (IM) is a premalignant condition. This study aimed to evaluate the correlation between endoscopic and histological findings of IM.
  
  
  METHODS
  The cases of IM were graded by conventional endoscopy, and biopsies were taken from the antrum and body of 1,333 subjects for histological IM diagnosis. Multivariate analyses were performed to identify the factors that affect the sensitivity of endoscopic IM diagnosis.
  
  
  RESULTS
  The sensitivity/specificity of endoscopic IM diagnosis based on histology was 24.0%/91.9% for the antrum and 24.2%/88.0% for the body. As indicated by multivariate analysis, the presence of endoscopic atrophic gastritis (AG) (odds ratio [OR], 4.73; 95% confidence interval [CI], 2.07 to 10.79) and the activity of mucosal inflammation (OR, 2.21; 95% CI, 1.08 to 4.54) were associated with the sensitivity of endoscopic IM diagnosis in the antrum, while the presence of endoscopic AG (OR, 8.02; 95% CI, 4.55 to 14.15), dysplasia (OR, 2.40; 95% CI, 1.07 to 5.39), and benign gastric ulcers (OR, 0.35; 95% CI, 0.15 to 0.081) were associated with the sensitivity of endoscopic IM diagnosis in the body.
  
  
  CONCLUSIONS
  As the sensitivity of endoscopic IM diagnosis was low, a high index of suspicion for IM is necessary in the presence of atrophy, and confirmation by histology is also necessary.
authors: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
authors: Ji Hwan
authors: JH
authors: Lim
authors: Nayoung
authors: N
authors: Kim
authors: Hye Seung
authors: HS
authors: Lee
authors: Gheeyoung
authors: G
authors: Choe
authors: So Young
authors: SY
authors: Jo
authors: Ilyoung
authors: I
authors: Chon
authors: Chiun
authors: C
authors: Choi
authors: Hyuk
authors: H
authors: Yoon
authors: Cheol Min
authors: CM
authors: Shin
authors: Young Soo
authors: YS
authors: Park
authors: Dong Ho
authors: DH
authors: Lee
authors: Hyun Chae
authors: HC
authors: Jung
keywords: Diagnosis; Endoscopy; Histology; Intestinal metaplasia