title: Clinical assessment of systolic myocardial deformations in dogs with chronic mitral valve insufficiency using two-dimensional speckle-tracking echocardiography.
abstract: OBJECTIVE
  The objective of this study was to clinically assess myocardial deformations in dogs with chronic mitral valve insufficiency (CMVI) using two-dimensional speckle-tracking echocardiography (2D-STE).
  
  
  METHODS
  87 dogs with CMVI.
  
  
  METHODS
  Dogs were placed into 1 of 3 classes, based on the International Small Animal Cardiac Health Council classification. In addition, 20 weight- and age-matched healthy dogs were enrolled as controls. The dogs were examined for myocardial deformations using 2D-STE, and strain and strain rate in the longitudinal, circumferential, and radial directions were evaluated.
  
  
  RESULTS
  Class II and III dogs had higher circumferential strain than class I dogs (P = 0.002 and P = 0.001, respectively) and controls (P < 0.001 and P < 0.001, respectively). Class III dogs had higher radial strain than class I dogs (P = 0.001) and controls (P < 0.001). Class III dogs had higher radial strain rate than class I dogs (P = 0.006) and controls (P = 0.001). Other deformations, including longitudinal deformations, were not significantly different between classes of CMVI or between CMVI dogs and controls.
  
  
  CONCLUSIONS
  In the clinical progression of CMVI in dogs, myocardial deformations, as assessed by 2D-STE, differed according to myocardial contractile direction. Thus, assessments of multidirectional myocardial deformations may be important for better assessment of clinical cardiac function in dogs with CMVI.
authors: Division of Veterinary Internal Medicine, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino-shi, Tokyo 180-8602, Japan. d01005@nvlu.ac.jp
authors: Ryohei
authors: R
authors: Suzuki
authors: Hirotaka
authors: H
authors: Matsumoto
authors: Takahiro
authors: T
authors: Teshima
authors: Hidekazu
authors: H
authors: Koyama
mesh_terms: D000818:Animals; D002908:Chronic Disease; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D004452:Echocardiography / Q000379:methods / Q000662:veterinary*; D005260:Female; D008297:Male; D008944:Mitral Valve Insufficiency / Q000473:pathology / Q000662:veterinary*; D009206:Myocardium / Q000473:pathology*; D013599:Systole