title: New drugs for methicillin-resistant Staphylococcus aureus: an update.
abstract: Methicillin-resistant Staphylococcus aureus (MRSA) remains a leading cause of bacterial infections worldwide, with a dwindling repertoire of effective antimicrobials active against it. This review aims to provide an update on novel anti-MRSA molecules currently under pre-clinical and clinical development, with emphasis on their mechanism of action. This review is limited to molecules that target the pathogen directly and does not detail immunomodulatory anti-infectives.
authors: Skirball Institute Program in Molecular Pathogenesis and Department of Microbiology, New York University Medical Center, NY 10016, USA.
authors: Krishan
authors: K
authors: Kumar
authors: Sidharth
authors: S
authors: Chopra
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology* / Q000627:therapeutic use; D055808:Drug Discovery / Q000639:trends; D006801:Humans; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents
keywords: MRSA; antibiotics; mechanism of action