title: Three-dimensional interactive and stereotactic atlas of head muscles and glands correlated with cranial nerves and surface and sectional neuroanatomy.
abstract: Three-dimensional (3D) relationships between head muscles and cranial nerves innervating them are complicated. Existing sources present these relationships in illustrations, radiologic scans, or autopsy photographs, which are limited for learning and use. Developed electronic atlases are limited in content, quality, functionality, and/or presentation. We create a truly 3D interactive, stereotactic and high quality atlas, which provides spatial relationships among head muscles, glands and cranial nerves, and correlates them to surface and sectional neuroanatomy. The head muscles and glands were created from a 3T scan by contouring them and generating 3D models. They were named and structured according to Terminologia anatomica. The muscles were divided into: extra-ocular, facial, masticatory and other muscles, and glands into mouth and other glands. The muscles, glands (and also head) were placed in a stereotactic coordinate system. This content was integrated with cranial nerves and neuroanatomy created earlier. To explore this complex content, a scalable user interface was designed with 12 modules including central nervous system (cerebrum, cerebellum, brainstem, spinal cord), cranial nerves, muscles, glands, arterial system, venous system, tracts, deep gray nuclei, ventricles, white matter, visual system, head. Anatomy exploration operations include compositing/decompositing, individual/group selection, 3D view-index mapping, 3D labeling, highlighting, distance measuring, 3D brain cutting, and axial/coronal/sagittal triplanar display. To our best knowledge, this is the first truly 3D, stereotactic, interactive, fairly complete atlas of head muscles, and the first attempt to create a 3D stereotactic atlas of glands. Its use ranges from education of students and patients to research to potential clinical applications.
authors: Biomedical Imaging Lab, Agency for Science Technology and Research, Singapore. wieslaw@sbic.a-star.edu.sg
authors: Wieslaw L
authors: WL
authors: Nowinski
authors: Beng Choon
authors: BC
authors: Chua
authors: Aleksandra
authors: A
authors: Johnson
authors: Guoyu
authors: G
authors: Qian
authors: Lan Eng
authors: LE
authors: Poh
authors: Su Hnin Wut
authors: SH
authors: Yi
authors: Aminah
authors: A
authors: Bivi
authors: Natalia G
authors: NG
authors: Nowinska
mesh_terms: D001271:Atlases as Topic; D003391:Cranial Nerves / Q000033:anatomy & histology*; D017352:Echo-Planar Imaging; D005152:Facial Muscles / Q000033:anatomy & histology; D006257:Head / Q000033:anatomy & histology*; D006801:Humans; D021621:Imaging, Three-Dimensional; D007765:Lacrimal Apparatus / Q000033:anatomy & histology*; D008410:Masticatory Muscles / Q000033:anatomy & histology; D018482:Muscle, Skeletal / Q000033:anatomy & histology*; D009445:Neuroanatomy / Q000379:methods*; D012469:Salivary Glands / Q000033:anatomy & histology*; D013238:Stereotaxic Techniques