title: The value of intermittent point-prevalence surveys of healthcare-associated infections for evaluating infection control interventions at Angkor Hospital for Children, Siem Reap, Cambodia.
abstract: BACKGROUND
  There are limited data on the epidemiology of paediatric healthcare-associated infection (HCAI) and infection control in low-income countries. We describe the value of intermittent point-prevalence surveys for monitoring HCAI and evaluating infection control interventions in a Cambodian paediatric hospital.
  
  
  METHODS
  Hospital-wide, point-prevalence surveys were performed monthly in 2011. Infection control interventions introduced during this period included a hand hygiene programme and a ventilator-associated pneumonia (VAP) care bundle.
  
  
  RESULTS
  Overall HCAI prevalence was 13.8/100 patients at-risk, with a significant decline over time. The highest HCAI rates (50%) were observed in critical care; the majority of HCAIs were respiratory (61%). Klebsiella pneumoniae was most commonly isolated and antimicrobial resistance was widespread. Hand hygiene compliance doubled to 51.6%, and total VAP cases/1000 patient-ventilator days fell from 30 to 10.
  
  
  CONCLUSIONS
  Rates of HCAI were substantial in our institution, and antimicrobial resistance a major concern. Point-prevalence surveys are effective for HCAI surveillance, and in monitoring trends in response to infection control interventions.
authors: Angkor Hospital for Children, Vithey Preah Sangreach Tep Vong & Um Chhay St., Sangkat Svay Dangkum Commune, Siem Reap, Cambodia. nicole.stoesser@ndm.ox.ac.uk
authors: N
authors: N
authors: Stoesser
authors: K
authors: K
authors: Emary
authors: S
authors: S
authors: Soklin
authors: K
authors: K
authors: Peng An
authors: S
authors: S
authors: Sophal
authors: S
authors: S
authors: Chhomrath
authors: N P J
authors: NP
authors: Day
authors: D
authors: D
authors: Limmathurotsakul
authors: P
authors: P
authors: Nget
authors: Y
authors: Y
authors: Pangnarith
authors: S
authors: S
authors: Sona
authors: V
authors: V
authors: Kumar
authors: C E
authors: CE
authors: Moore
authors: N
authors: N
authors: Chanpheaktra
authors: C M
authors: CM
authors: Parry
mesh_terms: D002160:Cambodia / Q000453:epidemiology; D003428:Cross Infection / Q000453:epidemiology* / Q000517:prevention & control; D006235:Hand Disinfection / Q000379:methods; D006776:Hospitals, Pediatric / Q000592:standards*; D006801:Humans; D017053:Infection Control / Q000379:methods*; D015995:Prevalence; D012044:Regression Analysis