title: Superficial pyoderma gangrenosum treated with infliximab: a case report.
abstract: We report a case of superficial pyoderma gangrenosum (SPG) that was successfully treated with infliximab. A 22-year-old man presented with several polycyclic, purplish red plaques with some crusting and well-defined edges on the bilateral lower extremities. Histology showed superficial and deep mixed inflammatory cell infiltrate with prominent neutrophils and scarring noted as a result of multiple sinus tract formations that were characteristic of SPG. After unsuccessful results with typical treatments (ie, steroids, antibiotics, immunosuppressants), the patient was successfully treated with infliximab.
authors: Nassau University Medical Center, East Meadow, New York, USA. humz84@gmail.com
authors: Hamza
authors: H
authors: Bhatti
authors: Nauman
authors: N
authors: Khalid
authors: Babar
authors: B
authors: Rao
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D006801:Humans; D000069285:Infliximab; D008297:Male; D017511:Pyoderma Gangrenosum / Q000188:drug therapy* / Q000473:pathology; D055815:Young Adult
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000911:Antibodies, Monoclonal; D000069285:Infliximab