title: Water-compatible 'aspartame'-imprinted polymer grafted on silica surface for selective recognition in aqueous solution.
abstract: Molecularly imprinted polymers selective for aspartame have been prepared using N-[2-ammonium-ethyl-piperazinium) maleimidopropane sulfonate copolymer bearing zwitterionic centres along the backbone via a surface-confined grafting procedure. Aspartame, a dipeptide, is commonly used as an artificial sweetener. Polymerisation on the surface was propagated by means of Michael addition reaction on amino-grafted silica surface. Electrostatic interactions along with complementary H-bonding and other hydrophobic interactions inducing additional synergetic effect between the template (aspartame) and the imprinted surface led to the formation of imprinted sites. The MIP was able to selectively and specifically take up aspartame from aqueous solution and certain pharmaceutical samples quantitatively. Hence, a facile, specific and selective technique using surface-grafted specific molecular contours developed for specific and selective uptake of aspartame in the presence of various interferrants, in different kinds of matrices is presented.
authors: Department of Chemistry, MMV, Banaras Hindu University, Varanasi, India. meenakshi_s4@rediffmail.com
authors: Meenakshi
authors: M
authors: Singh
authors: Abhishek
authors: A
authors: Kumar
authors: Nazia
authors: N
authors: Tarannum
mesh_terms: D000327:Adsorption; D001218:Aspartame / Q000302:isolation & purification*; D057927:Hydrophobic and Hydrophilic Interactions; D054802:Molecular Imprinting / Q000379:methods*; D058105:Polymerization; D011108:Polymers / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D013451:Sulfonic Acids / Q000737:chemistry; D013499:Surface Properties; D013549:Sweetening Agents / Q000302:isolation & purification*; D014867:Water / Q000737:chemistry
chemical_list: D011108:Polymers; D013451:Sulfonic Acids; D013549:Sweetening Agents; D014867:Water; D012822:Silicon Dioxide; D001218:Aspartame