title: [Dose and effect biomarkers in the diagnosis of asbestos-related diseases and health surveillance of exposed workers].
abstract: The aim of the study was to assess the reliability of the indicators of dose and effect in the health monitoring of asbestos exposed workers. In 49 cases out of 158 studied workers (31%) asbestos-related diseases were diagnosed following ATS criteria (2004). Using nonparametric statistical methods (permutation tests) 6 variables were analyzed with respect to asbestos-related diseases and working sectors, demonstrating a difference in the concentration of amphiboles (p < 0.01), greater in patients with asbestosis and workers involved in asbestos removal from railway carriages. There was not a correlation between mesothelin and amphiboles, chrysotile and total fibers concentrations (Spearman test).
authors: Medicina del Lavoro, Dipartimento di Scienze Mediche Chirurgiche e Neuroscienze, Università degli Studi di Siena, Viale Bracci 16, 53100 Siena.
authors: L
authors: L
authors: Montomoli
authors: R
authors: R
authors: Romeo
authors: A G
authors: AG
authors: Sisinni
authors: A C
authors: AC
authors: Serio
authors: V
authors: V
authors: Paolucci
authors: G
authors: G
authors: Scancarello
authors: L
authors: L
authors: Barabesi
authors: D
authors: D
authors: Orsi
authors: P
authors: P
authors: Sartorelli
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001195:Asbestosis / Q000175:diagnosis*; D015415:Biomarkers / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000175:diagnosis*; D016273:Occupational Exposure / Q000009:adverse effects*; D011159:Population Surveillance
chemical_list: D015415:Biomarkers