title: Prognostic factors for visual recovery after transsphenoidal pituitary adenectomy.
abstract: OBJECTIVE
  Pituitary adenomas often cause deficits in visual acuity (VA) and visual field (VF) due to compression of the optic chiasm. This study is to identify factors most likely to predict the prognosis of VA and VF after transsphenoidal pituitary adenectomy.
  
  
  METHODS
  Clinical records of patients who underwent transsphenoidal pituitary adenectomy were retrospectively reviewed. Data analysed included systemic and visual symptom duration, tumour size, presence of suprasellar tumour extension, histological classification of tumour, VA, and VF. VFs were determined using the Goldmann VF test and quantified according to methods outlined by the American Medical Association.
  
  
  RESULTS
  One-hundred and seventy eyes from 85 patients were included. Systemic and visual symptom duration, pre- and postoperative tumour size, and age did not correlate with postoperative VA or VF score. Patients with normal preoperative VA had a better postoperative VA than that of patients with preoperative VA of 20/30 or worse. Patients with normal preoperative VA had better postoperative VF score than that of patients with preoperative VA of 20/70 or worse. Postoperative VF score was lower in the preoperative ≥ 2 quadrant field loss group than in the ≤ 1 quadrant field loss group. Postoperative VA was worse in the ≥ 2 quadrant loss group than in the normal field group. Preoperative VA correlated with postoperative VA and VF score, and preoperative VF score correlated with postoperative VF score but not with VA.
  
  
  CONCLUSIONS
  Preoperative VA is a prognostic factor for postoperative VA and VF. Preoperative VF is predictive of postoperative VF and postoperative VA in cases with severe VF loss.
authors: Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Hospital , Seoul , Korea.
authors: Sangmoon
authors: S
authors: Lee
authors: Seong-Joon
authors: SJ
authors: Kim
authors: Young Suk
authors: YS
authors: Yu
authors: Yong Hwy
authors: YH
authors: Kim
authors: Sun Ha
authors: SH
authors: Paek
authors: Dong Gyu
authors: DG
authors: Kim
authors: Hee-Won
authors: HW
authors: Jung
mesh_terms: D000236:Adenoma / Q000150:complications / Q000473:pathology / Q000601:surgery*; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods*; D010911:Pituitary Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D011379:Prognosis; D020127:Recovery of Function / Q000502:physiology*; D012658:Sella Turcica / Q000473:pathology; D012737:Sex Factors; D013100:Sphenoid Bone / Q000601:surgery; D016896:Treatment Outcome; D014786:Vision Disorders / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D014787:Vision Tests; D014792:Visual Acuity / Q000502:physiology; D058609:Visual Field Tests; D014794:Visual Fields / Q000502:physiology; D055815:Young Adult