title: Bilateral ptosis as initial presentation of gliomatosis cerebri: case report.
abstract: Gliomatosis cerebri is a rare, diffuse glioma of neuroepithelial origin involving more than two cerebral lobes. Clinical presentation of gliomatosis cerebri is variable and depends on the degree, extent, and location of cortical involvement. Signs and symptoms related to supratentorial cortical involvement predominate and the diagnosis is reached through a combination of clinical, radiographic, and histopathological evaluations. This is a report of a young man who presented with visual problems and bilateral ptosis, which were eventually attributed to gliomatosis cerebri. Standard radiation and chemotherapy were administered but the patient eventually succumbed to the disease. The unique clinical presentation is discussed in light of this rare neoplasm of the central nervous system.
authors: Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, United States.
authors: Timothy
authors: T
authors: Kovanda
authors: Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, United States.
authors: John
authors: J
authors: Braca
authors: Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois, United States.
authors: Vikram
authors: V
authors: Prabhu
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D001763:Blepharoptosis / Q000209:etiology*; D001932:Brain Neoplasms / Q000150:complications* / Q000601:surgery / Q000628:therapy*; D059248:Chemoradiotherapy; D003131:Combined Modality Therapy; D003606:Dacarbazine / Q000031:analogs & derivatives / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004172:Diplopia / Q000209:etiology; D017809:Fatal Outcome; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D018302:Neoplasms, Neuroepithelial / Q000150:complications* / Q000601:surgery / Q000628:therapy*; D019635:Neurosurgical Procedures; D012640:Seizures / Q000209:etiology; D000077204:Temozolomide; D055815:Young Adult
chemical_list: D000927:Anticonvulsants; D018906:Antineoplastic Agents, Alkylating; D003606:Dacarbazine; D000077204:Temozolomide