title: Review of P-gp inhibition data in recently approved new drug applications: utility of the proposed [I(1) ]/IC(50) and [I(2) ]/IC(50) criteria in the P-gp decision tree.
authors: US Food and Drug Administration, Silver Spring, Maryland 20993, USA.
authors: Sheetal
authors: S
authors: Agarwal
authors: Vikram
authors: V
authors: Arya
authors: Lei
authors: L
authors: Zhang
mesh_terms: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000037:antagonists & inhibitors*; D003663:Decision Trees; D017277:Drug Approval; D004347:Drug Interactions; D004348:Drug Labeling; D006801:Humans; D020128:Inhibitory Concentration 50
chemical_list: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1