title: Limb salvage using advanced technologies: a case report.
abstract: Patients with severe acute and chronic lower extremity wounds often present a significant challenge in terms of limb salvage. In addition to control of infection, assuring adequate perfusion and providing standard wound care, advanced modalities are often required to facilitate final wound closure. We herein present a case study on a diabetic patient with gangrene and necrotising soft-tissue infection who underwent a forefoot pedal amputation to control the sepsis. Despite his non invasive vascular studies demonstrating poor healing potential at this level, he was not deemed suitable for revascularisation by our vascular surgeons and ankle-level amputation was recommended. Nonetheless, over a 5-month period using multiple advanced wound care therapies, wound closure was ultimately achieved.
authors: Podiatry Department, Carl T. Hayden VA Medical Center, Phoenix VA Health Care System, Phoenix, AZ, USA.
authors: Robert G
authors: RG
authors: Frykberg
authors: Rachel M
authors: RM
authors: O'Connor
authors: Arthur
authors: A
authors: Tallis
authors: Edward
authors: E
authors: Tierney
mesh_terms: D001684:Biological Dressings; D020099:Coated Materials, Biocompatible; D017719:Diabetic Foot / Q000150:complications / Q000473:pathology / Q000628:therapy*; D005734:Gangrene; D006801:Humans; D023821:Limb Salvage / Q000379:methods*; D008297:Male; D008875:Middle Aged; D018461:Soft Tissue Infections / Q000150:complications / Q000473:pathology / Q000628:therapy*; D058106:Wound Closure Techniques; D014945:Wound Healing
chemical_list: D020099:Coated Materials, Biocompatible; C512800:TransCyte
keywords: Advanced wound care therapies; Diabetic foot; Negative pressure wound therapy; Skin substitutes; Wound