title: Struma ovarii simulating ovarian sertoli cell tumor: a case report with literature review.
abstract: Struma ovarii, as a monodermal variant of ovarian teratoma, constitutes about less than 3% of ovarian teratomas. It is difficult to be macroscopically recognized. Multiple appearances under microscope serve as another reason to mislead the accurate pathologic evaluation. Here, we report an unusual case of struma ovarii occurred in a 77 years old woman, which is currently known as the oldest age for this disease. The frozen section morphologically showed sex cord like elements and was suspicious for a sex-cord stromal tumor, probably a Sertoli cell tumor. Final pathological diagnosis was confirmed as struma ovarii based on the typical morphologic thyroid follicles and immunohistochemical staining results.
authors: Obstetrics & Gynecology Hospital, Fudan University Shanghai, China. nyiping@yahoo.com.cn
authors: Yan
authors: Y
authors: Ning
authors: Fanbin
authors: F
authors: Kong
authors: Janiel M
authors: JM
authors: Cragun
authors: Wenxin
authors: W
authors: Zheng
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism; D003937:Diagnosis, Differential; D005260:Female; D005629:Frozen Sections; D006801:Humans; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D012707:Sertoli Cell Tumor / Q000175:diagnosis*; D013330:Struma Ovarii / Q000175:diagnosis* / Q000378:metabolism; D013954:Thyroglobulin / Q000378:metabolism; D013961:Thyroid Gland / Q000378:metabolism / Q000473:pathology; D014157:Transcription Factors
chemical_list: D014408:Biomarkers, Tumor; D004268:DNA-Binding Proteins; C504003:TTF1 protein, human; D014157:Transcription Factors; D013954:Thyroglobulin
keywords: Struma ovarii; ovary; sertoli cell tumor