title: Methylene acetal formation from 1,2- and 1,3-diols using an O,S-acetal, 1,3-dibromo-5,5-dimethylhydantoin, and BHT.
abstract: A mild and efficient method for formation of methylene acetals from 1,2- and 1,3-diols using methoxymethylphenylsulfide, 1,3-dibromo-5,5-dimethylhydantoin (DBDMH), and dibutylhydroxytoluene (BHT) is described. The use of BHT in this process suppresses side reactions and enables high-yielding formation of methylene acetals of various diols, including carbohydrate-type substrates.
authors: Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka 565-0871, Japan.
authors: Tomohiro
authors: T
authors: Maegawa
authors: Yasuyuki
authors: Y
authors: Koutani
authors: Kazuki
authors: K
authors: Otake
authors: Hiromichi
authors: H
authors: Fujioka
mesh_terms: D000080:Acetals / Q000138:chemical synthesis* / Q000737:chemistry; D000438:Alcohols / Q000737:chemistry*; D002084:Butylated Hydroxytoluene / Q000031:analogs & derivatives / Q000737:chemistry*; D006827:Hydantoins / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000080:Acetals; D000438:Alcohols; D006827:Hydantoins; D002084:Butylated Hydroxytoluene; C056578:1,3-dibromo-5,5-dimethylhydantoin