title: Relation of angiographic thrombus burden with electrocardiographic grade III ischemia in patients with ST-segment elevation myocardial infarction.
abstract: BACKGROUND
  We aimed to investigate the association between electrocardiographic (ECG) grade III ischemia and angiographic thrombus burden in patients with acute ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (pPCI).
  
  
  METHODS
  The study population consisted of 307 patients with STEMI. Baseline ECGs of the patients were analyzed for grade III ischemia; angiographic thrombus burden was assessed by thrombolysis in myocardial infarction thrombus classification.
  
  
  RESULTS
  A total of 108 (35%) patients had low thrombus burden whereas 199 (65%) patients had high thrombus burden. Grade III ischemia was more prevalent in patients with high thrombus burden (25.1% vs 11.1%, P = .004). Only grade III ischemia (odds ratio: 2.59, 95% confidence interval 1.24-5.39, P = .011) and history of coronary artery disease (CAD) were found to be the independent predictors of high thrombus burden.
  
  
  CONCLUSIONS
  Grade III ischemia on ECG and previous history of CAD were independent predictors of coronary thrombus burden in patients with STEMI who underwent pPCI.
authors: 1Department of Cardiology, Mustafa Kemal University Medical School, Hatay, Turkey.
authors: Mustafa
authors: M
authors: Kurt
authors: Mehmet Fatih
authors: MF
authors: Karakas
authors: Eyup
authors: E
authors: Buyukkaya
authors: Adnan Burak
authors: AB
authors: Akçay
authors: Nihat
authors: N
authors: Sen
mesh_terms: D000792:Angiography; D003328:Coronary Thrombosis / Q000097:blood / Q000209:etiology* / Q000473:pathology; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000473:pathology / Q000601:surgery; D017202:Myocardial Ischemia / Q000097:blood* / Q000473:pathology / Q000601:surgery; D062645:Percutaneous Coronary Intervention; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: ST-elevation myocardial infarction; grade III ischemia; thrombus burden