title: Poor desynchronisation of resting-state eyes-open cortical alpha rhythms in obese subjects without eating disorders.
abstract: OBJECTIVE
  Obese subjects without eating disorders were characterised by poor electroencephalographic (EEG) alpha rhythms during resting-state eye-closed condition (Babiloni et al., 2011b). Is this true also for the desynchronisation of alpha rhythms during resting-state eyes opening?
  
  
  METHODS
  EEG data were recorded in 15 underweight, 20 normal-weight, and 18 overweight/obese subjects during resting-state eyes-closed and -open conditions. EEG sources were estimated by LORETA for alpha 1 (8-10.5 Hz) and alpha 2 (10.5-13 Hz). The alpha desynchronisation was calculated as the difference eyes-open minus -closed condition.
  
  
  RESULTS
  The occipital alpha 1 desynchronisation was lower in overweight/obese and underweight subjects compared with normal-weight subjects (p < 0.000005). The same was true for parietal, occipital and temporal alpha 2 (10.5-13 Hz) desynchronisation (p < 0.000002). The parietal and temporal alpha 1 desynchronisation was lower in overweight/obese than in normal-weight subjects (p < 0.00001). These effects spatially matched those observed in the resting-state eyes-closed condition.
  
  
  CONCLUSIONS
  Subjects with abnormal weight and normal eating behaviour are characterised by poor alpha desynchronisation during resting-state eyes opening.
  
  
  CONCLUSIONS
  Obese subjects without eating disorders show abnormal mechanisms of cortical neural synchronisation and desynchronisation of alpha rhythms in the resting state condition.
authors: Ospedale San Raffaele Pisana, Rome, Italy.
authors: Claudio
authors: C
authors: Del Percio
authors: Antonio I
authors: AI
authors: Triggiani
authors: Nicola
authors: N
authors: Marzano
authors: Anna
authors: A
authors: Valenzano
authors: Mario
authors: M
authors: De Rosas
authors: Annamaria
authors: A
authors: Petito
authors: Antonello
authors: A
authors: Bellomo
authors: Brunello
authors: B
authors: Lecce
authors: Ciro
authors: C
authors: Mundi
authors: Francesco
authors: F
authors: Infarinato
authors: Andrea
authors: A
authors: Soricelli
authors: Cristina
authors: C
authors: Limatola
authors: Giuseppe
authors: G
authors: Cibelli
authors: Claudio
authors: C
authors: Babiloni
mesh_terms: D000293:Adolescent; D000328:Adult; D000513:Alpha Rhythm / Q000502:physiology*; D000886:Anthropometry; D015992:Body Mass Index; D002540:Cerebral Cortex / Q000503:physiopathology*; D003627:Data Interpretation, Statistical; D058407:Electroencephalography Phase Synchronization / Q000502:physiology*; D001068:Feeding and Eating Disorders / Q000503:physiopathology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D009483:Neuropsychological Tests; D009765:Obesity / Q000503:physiopathology*; D050177:Overweight / Q000503:physiopathology / Q000523:psychology; D013851:Thinness / Q000503:physiopathology / Q000523:psychology; D055815:Young Adult