title: Ultrathin PEGylated W18O49 nanowires as a new 980 nm-laser-driven photothermal agent for efficient ablation of cancer cells in vivo.
abstract: A new photothermal coupling agent for photothermal ablation (PTA) therapy of tumors is developed based on ultrathin PEGylated W18O49 nanowires. After being injected with the nanowire solution, the in vivo tumors exhibit a rapid temperature rise to 50.0 ± 0.5 °C upon irradiation with NIR laser light at a safe, low intensity (0.72 W cm(-2)) for 2 min (left-hand mouse in the figure),), resulting in the efficient PTA of cancer cells in vivo in 10 min.
authors: State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, P R of China. zgchen@dhu.edu.cn
authors: Zhigang
authors: Z
authors: Chen
authors: Qian
authors: Q
authors: Wang
authors: Huanli
authors: H
authors: Wang
authors: Lisha
authors: L
authors: Zhang
authors: Guosheng
authors: G
authors: Song
authors: Linlin
authors: L
authors: Song
authors: Junqing
authors: J
authors: Hu
authors: Hongzhi
authors: H
authors: Wang
authors: Jianshe
authors: J
authors: Liu
authors: Meifang
authors: M
authors: Zhu
authors: Dongyuan
authors: D
authors: Zhao
mesh_terms: D000818:Animals; D006367:HeLa Cells; D006801:Humans; D007259:Infrared Rays; D051379:Mice; D016513:Mice, SCID; D053770:Nanowires / Q000737:chemistry* / Q000627:therapeutic use / Q000633:toxicity; D009369:Neoplasms / Q000628:therapy; D010087:Oxides / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D020349:Surface Plasmon Resonance; D013696:Temperature; D014183:Transplantation, Heterologous; D014414:Tungsten / Q000737:chemistry*
chemical_list: D010087:Oxides; D011092:Polyethylene Glycols; C511604:tungsten oxide; D014414:Tungsten