title: Superhydrophobic surfaces allow probing of exosome self organization using X-ray scattering.
abstract: Drops of exosome dispersions from healthy epithelial colon cell line and colorectal cancer cells were dried on a superhydrophobic PMMA substrate. The residues were studied by small- and wide-angle X-ray scattering using both a synchrotron radiation micrometric beam and a high-flux table-top X-ray source. Structural differences between healthy and cancerous cells were detected in the lamellar lattices of the exosome macro-aggregates.
authors: Istituto Italiano di Tecnologia-IIT, Nanostructures Department, Via Morego 30, 16163 Genova, Italy.
authors: Angelo
authors: A
authors: Accardo
authors: Luca
authors: L
authors: Tirinato
authors: Davide
authors: D
authors: Altamura
authors: Teresa
authors: T
authors: Sibillano
authors: Cinzia
authors: C
authors: Giannini
authors: Christian
authors: C
authors: Riekel
authors: Enzo
authors: E
authors: Di Fabrizio
mesh_terms: D045744:Cell Line, Tumor; D015179:Colorectal Neoplasms; D063326:Exosome Multienzyme Ribonuclease Complex / Q000648:ultrastructure*; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D019904:Polymethyl Methacrylate / Q000737:chemistry*; D012542:Scattering, Radiation; D014965:X-Rays
chemical_list: D019904:Polymethyl Methacrylate; D063326:Exosome Multienzyme Ribonuclease Complex