title: Insomnia symptoms in South Florida military veterans with epilepsy.
abstract: BACKGROUND
  Despite the high prevalence of insomnia in veterans with epilepsy, it remains understudied. Our aim was to identify the associations of insomnia with epilepsy, comorbidities, and treatment-related variables in South Florida veterans.
  
  
  METHODS
  We performed a cross-sectional analysis of veterans attending an epilepsy clinic over 18 months. Participants completed standardized assessments of seizure and sleep. Insomnia was defined as 1) difficulty with sleep onset, maintenance, or premature awakenings with daytime consequences or 2) sedative-hypnotic use on most nights of the previous month.
  
  
  RESULTS
  One hundred sixty-five veterans (87% male, age 56 ± 15 years) were included: 66 reporting insomnia (40%). In logistic regression analysis, insomnia was significantly associated with post-traumatic seizure etiology, lamotrigine prescription, and mood and psychotic disorders. Female gender and levetiracetam treatment were associated with lower odds for insomnia.
  
  
  CONCLUSIONS
  Insomnia was associated with post-traumatic epilepsy, mood/psychotic comorbidities, and antiepileptic regimen. Insomnia represents an under-recognized opportunity to improve comprehensive epilepsy care.
authors: Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.
authors: M R
authors: MR
authors: Lopez
authors: J Y
authors: JY
authors: Cheng
authors: A M
authors: AM
authors: Kanner
authors: D Z
authors: DZ
authors: Carvalho
authors: J A
authors: JA
authors: Diamond
authors: D M
authors: DM
authors: Wallace
mesh_terms: D000328:Adult; D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use; D015897:Comorbidity; D003430:Cross-Sectional Studies; D004827:Epilepsy / Q000188:drug therapy / Q000453:epidemiology*; D005260:Female; D005431:Florida / Q000453:epidemiology; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D008889:Military Personnel; D012189:Retrospective Studies; D007319:Sleep Initiation and Maintenance Disorders / Q000188:drug therapy / Q000453:epidemiology*; D014728:Veterans
chemical_list: D000927:Anticonvulsants