title: Evaluation of phytotoxicity and genotoxicity of nitrobenzene with a battery of Vicia faba assay system.
abstract: Nitrobenzene (NB) is an important organic compound intermediate that is used widely in industry. In the present study, to evaluate the phytotoxicity and genotoxicity of NB on plants, Vicia faba was exposed to increasing concentrations of NB (5 mg L(-1) , 10 mg L(-1) , 25 mg L(-1) , 50 mg L(-1) , and 100 mg L(-1) ). The data revealed that germination rate and radicle length of V. faba seedlings were promoted by low NB concentrations and short exposure periods, whereas these parameters were inhibited at greater NB concentrations and longer exposures. When assessed by mitotic index, micronucleus, and chromosomal aberration assays, NB showed dose-dependent genotoxicity at 0 mg L(-1) to 50 mg L(-1).
authors: Key Laboratory of Molecular and Cytogenetics, College of Life Sciences and Technology, Harbin Normal University, Heilongjiang Province, China.
authors: Jun
authors: J
authors: Ma
authors: Donglin
authors: D
authors: Guo
authors: Wenyue
authors: W
authors: Su
authors: Dan
authors: D
authors: Wang
authors: Changhong
authors: C
authors: Guo
mesh_terms: D002869:Chromosome Aberrations; D004249:DNA Damage; D015162:Micronucleus Tests; D009153:Mutagens / Q000633:toxicity; D009578:Nitrobenzenes / Q000633:toxicity*; D018517:Plant Roots / Q000187:drug effects / Q000235:genetics; D036226:Seedlings / Q000235:genetics; D012989:Soil Pollutants / Q000633:toxicity*; D031307:Vicia faba / Q000187:drug effects* / Q000235:genetics
chemical_list: D009153:Mutagens; D009578:Nitrobenzenes; D012989:Soil Pollutants; C036077:nitrobenzene