title: Metastatic gastrinoma in a pediatric patient with Zollinger-Ellison syndrome.
abstract: Metastatic neuroendocrine tumors of childhood are extremely rare, and as such present diagnostic and therapeutic challenges. Here, we report a case of gastrinoma with extensive hepatic metastases in a pediatric patient with Zollinger-Ellison Syndrome who underwent orthotopic liver transplant followed by cytotoxic chemotherapy, somatostatin analog therapy, and immune modulation.
authors: *Section of Hematology/Oncology, Department of Pediatrics †Yale Stem Cell Center, Yale University School of Medicine ‡Section of Transplantation and Immunology, Department of Surgery §Yale New Haven Transplant Center, New Haven, CT.
authors: Stephanie A
authors: SA
authors: Massaro
authors: Sukru H
authors: SH
authors: Emre
mesh_terms: D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D015408:Gastrinoma / Q000150:complications / Q000556:secondary* / Q000601:surgery; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications / Q000556:secondary* / Q000601:surgery; D016031:Liver Transplantation; D010190:Pancreatic Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D015043:Zollinger-Ellison Syndrome / Q000150:complications*