title: An Enhancing Effect of Gold Nanoparticles on the Lethal Action of 2450 MHz Electromagnetic Radiation in Microwave Oven.
abstract: Today, there is an increasing interest in the use of metal nanoparticles in health sciences. Amongst all nanoparticles, the gold nanoparticles have been known to kill the cancer cells under hyperthermic condition by near-infrared frequency electromagnetic waves. On the other hand, although there are different physiochemical methods for disinfection of microbial pollution, however applications of irradiated gold nanoparticles against microorganisms have not yet been investigated. In this study, gold nanoparticles were prepared using D-glucose and characterized (particle size <26 nm). In the next step, the enhancing effect of the non toxic level of gold nanoparticles (50 µg/mL) on the antimicrobial activity of 2450 MHz electromagnetic radiation generated at a microwave oven operated at low power (100 W), was investigated by time-kill course assay against Staphylococcus aureus (S.aureus) ATCC 29737. The results showed that application of gold nanoparticles can enhance the lethal effect of low power microwave in a very short exposure time (5 s).
authors: Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
authors: Kamyar
authors: K
authors: Mollazadeh-Moghaddam
authors: Bardia Varasteh
authors: BV
authors: Moradi
authors: Reza
authors: R
authors: Dolatabadi-Bazaz
authors: Mojtaba
authors: M
authors: Shakibae
authors: Ahmad Reza
authors: AR
authors: Shahverdi
keywords: Antimicrobial effect; Electromagnetic radiation; Gold nanoparticles; Microwave; Staphylococcus aureus