title: Molecular and genetic aspects of protein cold denaturation.
abstract: The phenomenon of cold-induced denaturation of proteins is reviewed. Examples of low temperature-induced changes in quaternary, tertiary and secondary structure of protein molecules are cited. Genetic aspects of cold-stability and functioning of structural proteins and enzymes from cold-tolerant organisms under low temperature conditions are discussed. Disorganisation of supramolecular assemblies under low-temperature influence is considered as one of the key factors contributing to cell cold-induced injuries.
authors: Institute for Problems of Cryobiology and Cryomedicine, National Academy of Sciences of Ukraine, Kharkov, Ukraine.
authors: A K
authors: AK
authors: Gulevsky
authors: L I
authors: LI
authors: Relina
mesh_terms: D000064:Acclimatization; D000818:Animals; D003080:Cold Temperature; D006801:Humans; D011487:Protein Conformation; D011489:Protein Denaturation; D055550:Protein Stability; D011506:Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism
chemical_list: D011506:Proteins