title: Pancreas transplantation: a single-institution experience in Japan.
abstract: OBJECTIVE
  We herein report our experience with pancreas transplantation in 26 patients at a single institution in Japan between August 2001 and December 2011.
  
  
  METHODS
  We reviewed the medical records of 26 pancreas transplantations performed in our institute.
  
  
  RESULTS
  The early complications (within 2 weeks) included one graft venous thrombosis, one arterial thrombosis, and two reoperations for bleeding. Of the 26 pancreas transplant recipients, five lost pancreas graft function. Of 24 simultaneous pancreas-kidney recipients, three lost kidney graft function due to noncompliance. The patient, pancreas, and kidney survival rates were 100, 96 and 93 % at 1 year; 100, 80 and 93 % at 5 years; and 100, 67 and 68 % at 10 years, respectively. Of all these complications, venous thrombosis after pancreas transplantation was the most critical.
  
  
  CONCLUSIONS
  As the largest series of pancreas transplantations in a single institution in Japan, our series yielded better results than the worldwide data recorded by the International Pancreas Transplant Registry. Routine postoperative anticoagulation therapy is not necessary for the prevention of graft thrombosis if sufficient fluid infusion is strictly controlled and the graft blood flow is frequently monitored. When graft thrombosis occurs, both early detection and appropriate intervention are extremely important if the pancreas graft is to survive.
authors: Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
authors: Yasuhiro
authors: Y
authors: Okabe
authors: Hidehisa
authors: H
authors: Kitada
authors: Yoshifumi
authors: Y
authors: Miura
authors: Takehiro
authors: T
authors: Nishiki
authors: Kei
authors: K
authors: Kurihara
authors: Sayako
authors: S
authors: Kawanami
authors: Soshi
authors: S
authors: Terasaka
authors: Keizo
authors: K
authors: Kaku
authors: Hiroshi
authors: H
authors: Noguchi
authors: Atsushi
authors: A
authors: Sugitani
authors: Masao
authors: M
authors: Tanaka
mesh_terms: D000328:Adult; D015992:Body Mass Index; D003956:Dialysis; D005260:Female; D005440:Fluid Therapy; D006085:Graft Survival; D006400:Hematocrit; D006801:Humans; D007564:Japan; D008297:Male; D008991:Monitoring, Physiologic; D010179:Pancreas / Q000098:blood supply*; D016035:Pancreas Transplantation / Q000401:mortality; D011183:Postoperative Complications / Q000175:diagnosis / Q000517:prevention & control*; D012039:Regional Blood Flow; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D020246:Venous Thrombosis / Q000175:diagnosis / Q000517:prevention & control*