title: Hypercalcemia with renal failure.
abstract: We report a cse of nephrocalcinosis with renal failure which on evaluation was found to have hypercalcemia. Further investigations showed an inappropriately normal intact parathormone (iPTH) and 1,25 dihydroxy-vitamin D level in the setting of renal failure. Probing for a cause of non-PTH mediated hypercalcemia led to the diagnosis of sarcoidosis. Treatment with glucocorticoids could partially reverse the renal failure and control the hypercalcemia. This case illustrates the importance of careful interpretation of laboratory parameters especially levels of iPTH and vitamin D metabolites in renal failure.
authors: Department of Endocrinology and Diabetes, Amrita Institute of Medical Sciences, Cochin 682041, Kerala, India.
authors: Nisha
authors: N
authors: Bhavani
authors: Valiyaparambil Pavithran
authors: VP
authors: Praveen
authors: Rohinivilasam Vasukutty
authors: RV
authors: Jayakumar
authors: Vasantha
authors: V
authors: Nair
authors: Mangath
authors: M
authors: Muraleedharan
authors: Harish
authors: H
authors: Kuma
authors: Ambika Gopalakrishnan
authors: AG
authors: Unnikrishnan
authors: Vadayath Usha
authors: VU
authors: Menon
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D054559:Hyperphosphatemia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009397:Nephrocalcinosis / Q000209:etiology; D010281:Parathyroid Hormone / Q000097:blood; D011239:Prednisolone / Q000627:therapeutic use; D012507:Sarcoidosis / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D013163:Splenomegaly / Q000209:etiology
chemical_list: D005938:Glucocorticoids; D010281:Parathyroid Hormone; D011239:Prednisolone