title: The influence of food intake on liver stiffness values assessed by acoustic radiation force impulse elastography-preliminary results.
abstract: The present study assessed the influence of food intake on acoustic radiation force impulse elastography (ARFI) measurements. Seventy-three healthy volunteers were included: 57 subjects in the study group (on whom ARFI measurements were performed first in fasting condition, followed by measurements made 1h and 3h after food intake); and 16 subjects in the control group (on whom ARFI measurements were performed 3 times during a 3-h interval without eating). All subjects included in the study group received the same standard solid meal. In the study group, the mean liver stiffness (LS) values by ARFI increased significantly 1 h after food intake (1.51 ± 0.40 m/s vs. 1.27 ± 0.23, p = 0.003), but 3 h after the meal the differences were no longer significant (1.46 ± 0.51 vs. 1.27 ± 0.23, p = 0.06). In the control group, the mean LS values were similar in all 3 measurements. In conclusion, food intake significantly increased the LS values, thus ARFI measurements should be performed in fasting conditions.
authors: Department of Gastroenterology and Hepatology, University of Medicine and Pharmacy, Timişoara, Romania. alinamircea.popescu@gmail.com
authors: Alina
authors: A
authors: Popescu
authors: Simona
authors: S
authors: Bota
authors: Ioan
authors: I
authors: Sporea
authors: Roxana
authors: R
authors: Sirli
authors: Mirela
authors: M
authors: Danila
authors: Sebastian
authors: S
authors: Racean
authors: Dragos
authors: D
authors: Suseanu
authors: Oana
authors: O
authors: Gradinaru
authors: Cristian
authors: C
authors: Ivascu Siegfried
mesh_terms: D000328:Adult; D016477:Artifacts; D004435:Eating / Q000502:physiology*; D055119:Elastic Modulus / Q000502:physiology; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008099:Liver / Q000000981:diagnostic imaging* / Q000502:physiology*; D008297:Male; D010865:Pilot Projects; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity