title: Successful immunotherapy in life-threatening parvovirus B19 infection in a child.
abstract: We report a case of an immunocompetent child who developed parvovirus B19 infection complicated by autoinflammatory disease with myocarditis, tamponade and macrophage activation syndrome. He recovered with immunotherapy including prednisone, immunoglobulins, cyclosporin and anakinra (anti-interleukin-1). The report shows that parvovirus can provoke severe systemic inflammation with acute heart injury and that anti-interleukin-1 might be considered in such parvovirus-related inflammation.
authors: Service de Néphrologie, Dermatologie et Rhumatologie Pédiatrique, HFME, Hôpital Louis Pradel, Bron, France.
authors: Marine
authors: M
authors: Butin
authors: Yahia
authors: Y
authors: Mekki
authors: Alice
authors: A
authors: Phan
authors: Geneviève
authors: G
authors: Billaud
authors: Sylvie
authors: S
authors: Di Filippo
authors: Etienne
authors: E
authors: Javouhey
authors: Pierre
authors: P
authors: Cochat
authors: Alexandre
authors: A
authors: Belot
mesh_terms: D001327:Autoimmune Diseases / Q000150:complications*; D002648:Child; D006801:Humans; D007155:Immunologic Factors / Q000008:administration & dosage; D007167:Immunotherapy / Q000379:methods*; D008297:Male; D010322:Parvoviridae Infections / Q000175:diagnosis / Q000628:therapy* / Q000821:virology*; D016732:Parvovirus B19, Human / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D007155:Immunologic Factors