title: [Behaviour of HIV/AIDS-related lymphoma in Pedro Kouri Institute. 2004-2005].
abstract: A prospective and descriptive study of 20 patients infected with HIV and admitted to "Pedro Kouri" Institute of Tropical Disease after a diagnosis of lymphoma was conducted. They were all evaluated at the onset of diagnosis by a thorough medical record exam and supportive studies such as complete blood count, globular sedimentation speed, CD4+ count, lactic acid dehydrogenase, HIV viral load, cytology and biopsy. Of this number, 85% presented with CD4+ count under 350 cell/mm3 at the time of diagnosis; however, only 55% showed viral loads exceeding 50,000 copies/mL. The predominant histological subtype was large diffuse cells and the most frequent location was the extrapulmonary site in 70% of cases. It called our attention that high levels of lactic acid dehydrogenase and extrapulmonary location of tumors were related. Statistically significant association was found (p < 0.05) between immunosuppresion condition of the patients given by CD4+ count below 350 cell/mm3 and advanced staging of the tumoral disease (stages III and IV).
authors: Instituto de Medicina Tropical Pedro Kourí. miralles@ipk.sld.cu
authors: Fernando
authors: F
authors: Miralles Alonso
authors: Lilia María
authors: LM
authors: Ortega González
authors: Lisset
authors: L
authors: Oropesa González
authors: Rodríguez Delgado
authors: RD
authors: Francisco
authors: Virginia Capó
authors: VC
authors: de Paz
mesh_terms: D000047:Academies and Institutes; D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood; D001799:Blood Sedimentation; D018791:CD4 Lymphocyte Count; D003462:Cuba / Q000453:epidemiology; D005006:Ethnicity / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007770:L-Lactate Dehydrogenase / Q000097:blood; D016483:Lymphoma, AIDS-Related / Q000097:blood / Q000453:epidemiology* / Q000276:immunology / Q000473:pathology; D008297:Male; D009367:Neoplasm Staging; D011446:Prospective Studies; D012307:Risk Factors; D019562:Viral Load; D014766:Viremia / Q000453:epidemiology; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor; D007770:L-Lactate Dehydrogenase