title: The effect of high-intensity aerobic interval training on postinfarction left ventricular remodelling.
abstract: This is the third in a series of case studies on an individual with normal coronaries who sustained an idiopathic acute myocardial infarction . Bilateral pulmonary emboli almost 2 years post-myocardial infarction (MI) revealed coagulopathy as the cause. The original MI resulted in 16% myocardial scar tissue. An increasing number of patients are surviving MI, hence the burden for healthcare often shifts to heart failure. Accumulating evidence suggests high-intensity aerobic interval exercise (AHIT) is efficacious in improving cardiac function in health and disease. However, its impact on MI scar has never been assessed. Accordingly, the 50-year-old subject of this case study undertook 60 weeks of regular AHIT. Successive cardiac MRI results demonstrate, for the first time, a decrease in MI scar with exercise and, alongside mounting evidence of high efficacy and low risk, suggests AHIT may be increasingly important in future prevention and reversing of disease and or amelioration of symptoms.
authors: Centre for Sports Medicine and Human Performance, School of Sport and Education, Brunel University, Uxbridge, UK. richard.godfrey@brunel.ac.uk
authors: Richard
authors: R
authors: Godfrey
authors: Thomas
authors: T
authors: Theologou
authors: Santo
authors: S
authors: Dellegrottaglie
authors: Sukumaran
authors: S
authors: Binukrishnan
authors: Jay
authors: J
authors: Wright
authors: Gregory
authors: G
authors: Whyte
authors: Georgina
authors: G
authors: Ellison
mesh_terms: D015444:Exercise / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000473:pathology / Q000503:physiopathology / Q000534:rehabilitation*; D009206:Myocardium / Q000473:pathology; D020257:Ventricular Remodeling / Q000502:physiology*