title: Association of labor induction or stimulation with infant mortality in women with failed versus successful trial of labor after prior cesarean.
abstract: OBJECTIVE
  To compare infant mortality rates among women with a failed versus successful trial of labor after cesarean (TOLAC) following labor induction or stimulation.
  
  
  METHODS
  Using US linked birth and infant death cohort data (2000-2004), we identified women who delivered non-anomalous singleton births at 34-41 weeks with TOLAC whose labors were induced or stimulated. Multivariable log-binomial regression models were fitted to estimate the association between TOLAC success and infant mortality.
  
  
  RESULTS
  Of the 164,113 women who underwent TOLAC, 41% were unsuccessful. After adjustment for potential confounding factors, a failed TOLAC was associated with a 1.4 fold (95% confidence interval [CI] 1.1, 1.7) increased risk of infant mortality.
  
  
  CONCLUSIONS
  Among women undergoing labor induction or stimulation, a failed TOLAC is associated with higher likelihood of infant mortality.
authors: Department of Quantitative Health Science, University of Massachusetts Medical School, Worcester, MA, USA.
authors: Han-Yang
authors: HY
authors: Chen
authors: Suneet P
authors: SP
authors: Chauhan
authors: William A
authors: WA
authors: Grobman
authors: Cande V
authors: CV
authors: Ananth
authors: Anthony M
authors: AM
authors: Vintzileos
authors: Alfred Z
authors: AZ
authors: Abuhamad
mesh_terms: D000293:Adolescent; D000328:Adult; D002585:Cesarean Section; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007751:Labor, Induced / Q000009:adverse effects*; D016013:Likelihood Functions; D011247:Pregnancy; D017211:Treatment Failure; D014219:Trial of Labor; D014481:United States / Q000453:epidemiology; D055815:Young Adult