title: Biodamage via shock waves initiated by irradiation with ions.
abstract: Radiation damage following the ionising radiation of tissue has different scenarios and mechanisms depending on the projectiles or radiation modality. We investigate the radiation damage effects due to shock waves produced by ions. We analyse the strength of the shock wave capable of directly producing DNA strand breaks and, depending on the ion's linear energy transfer, estimate the radius from the ion's path, within which DNA damage by the shock wave mechanism is dominant. At much smaller values of linear energy transfer, the shock waves turn out to be instrumental in propagating reactive species formed close to the ion's path to large distances, successfully competing with diffusion.
authors: Frankfurt Institute for Advanced Studies, Frankfurt am Main, Germany. surdutov@oakland.edu
authors: Eugene
authors: E
authors: Surdutovich
authors: Alexander V
authors: AV
authors: Yakubovich
authors: Andrey V
authors: AV
authors: Solov'yov
mesh_terms: D004247:DNA / Q000528:radiation effects*; D004249:DNA Damage; D019220:High-Energy Shock Waves; D018499:Linear Energy Transfer; D056004:Molecular Dynamics Simulation; D009707:Nucleosomes / Q000528:radiation effects; D011839:Radiation, Ionizing
chemical_list: D009707:Nucleosomes; D004247:DNA