title: Isolation and structural elucidation of chondrosterins F-H from the marine fungus Chondrostereum sp.
abstract: The marine fungus Chondrostereum sp. was collected from a soft coral of the species Sarcophyton tortuosum from the South China Sea. Three new compounds, chondrosterins F-H (1, 4 and 5), together with three known compounds, incarnal (2), arthrosporone (3), and (2E)-decene-4,6,8-triyn-1-ol (6), were isolated. Their structures were elucidated primarily based on NMR and MS data. Incarnal (2) exhibited potent cytotoxic activity against various cancer cell lines.
authors: School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China. lanwj@mail.sysu.edu.cn
authors: Hou-Jin
authors: HJ
authors: Li
authors: Ting
authors: T
authors: Chen
authors: Ying-Lu
authors: YL
authors: Xie
authors: Wen-Dan
authors: WD
authors: Chen
authors: Xiao-Feng
authors: XF
authors: Zhu
authors: Wen-Jian
authors: WJ
authors: Lan
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000382:microbiology; D000970:Antineoplastic Agents / Q000737:chemistry*; D001487:Basidiomycota / Q000737:chemistry / Q000378:metabolism*; D045744:Cell Line, Tumor; D006801:Humans; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D012717:Sesquiterpenes; C583594:chondrosterin F; C583597:chondrosterin G; C583596:chondrosterin H