title: Prospective study of transobturator mesh kit (Prolift™) in pelvic reconstructive surgery with vaginal hysterectomy after 3 years' follow-up.
abstract: OBJECTIVE
  This study is to analyze prospectively the anatomical and functional outcomes of transvaginal pelvic reconstructive surgery using the Prolift™ system for pelvic organ prolapse (POP) with hysterectomy.
  
  
  METHODS
  A prospective, observational, noncomparative study was conducted in 80 patients with prolapse ≥ 2. Postoperative pelvic organ prolapse quantification stage was the main outcome measure. Anatomical cure was defined as vaginal vault stage 0 and improvement as stage 1. Secondary outcomes include pelvic floor distress inventory-20, incontinence impact questionnaire short form-7, and pelvic floor impact questionnaire short form-7.
  
  
  RESULTS
  A total of 80 patients were recruited. The cure and improvement rates were 96.3 % (77/80) and 3.7 % (3/80) respectively at 1 year. At the follow-up of 3-years, the cure rates were 93.3 % (70/75). Among the five patients, three had stage 2 anterior wall prolapse, two had stage 2 posterior wall prolapse. Only one patient with intraoperative adverse event (rectal perforation) was encountered. Postoperative complications included prolonged catheterization in three patients (3.7 %), postoperative stress urinary incontinence in five patients (6.25 %) and asymptomatic mesh extrusions in five patients (6.25 %). All of them occurred within 1 year follow-up. Significant improvements in quality of life were detected at 1 and 3 years compared with baseline.
  
  
  CONCLUSIONS
  The total Prolift™ system surgery represents a safe, simple and useful treatment for severe POP with satisfactory objective clinical outcomes.
authors: Department of Obstetrics and Gynaecology, Fu Zhou General Hospital, 156, xi'er huan North Road, Fu Zhou, 350025, Fujian, China.
authors: Feng-Mei
authors: FM
authors: Wang
authors: Chun-Ni
authors: CN
authors: He
authors: Yan-Feng
authors: YF
authors: Song
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007045:Hysterectomy, Vaginal / Q000009:adverse effects; D008875:Middle Aged; D059952:Pelvic Floor Disorders / Q000150:complications / Q000601:surgery*; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D011446:Prospective Studies; D011475:Prosthesis Failure / Q000209:etiology; D011788:Quality of Life; D013526:Surgical Mesh / Q000009:adverse effects; D011795:Surveys and Questionnaires; D014550:Urinary Incontinence, Stress / Q000209:etiology