title: An 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid)-immobilized electrode for the simultaneous detection of dopamine and uric acid in the presence of ascorbic acid.
abstract: An 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS)-immobilized carbon nanotube (CNT) electrode was used to simultaneously detect dopamine (DA) and uric acid (UA) in the presence of ascorbic acid (AA) with differential pulse voltammetry. When ABTS was immobilized onto the CNT electrode in the presence of DA, UA and 100 μM AA, the sensitivity to DA increased from 0.600 (±0.013) to 1.334 (±0.010) μA/μM in the concentration ranges of 0.90-10 μM and 1.87-20 μM, respectively, and the sensitivity to UA increased from 0.030 (±0.005) to 0.078 (±0.006) μA/μM in the concentration ranges of 2.16-240 μM and 3.07-400 μM, respectively. These findings demonstrate that the ABTS-immobilized CNT electrode attained a higher sensitivity to UA and also a wider linear range of concentrations.
authors: Department of Chemical Engineering, National Cheng Kung University, 1 University Road, Tainan City 70101, Taiwan.
authors: Yi-Kai
authors: YK
authors: Chih
authors: Ming-Chang
authors: MC
authors: Yang
mesh_terms: D001205:Ascorbic Acid / Q000032:analysis; D052160:Benzothiazoles / Q000737:chemistry*; D058266:Dielectric Spectroscopy; D004298:Dopamine / Q000032:analysis / Q000097:blood*; D015259:Dopamine Agents / Q000032:analysis / Q000097:blood*; D055664:Electrochemical Techniques / Q000295:instrumentation*; D004566:Electrodes; D006801:Humans; D037742:Nanotubes, Carbon / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013451:Sulfonic Acids / Q000737:chemistry*; D014527:Uric Acid / Q000032:analysis / Q000097:blood*
chemical_list: D052160:Benzothiazoles; D015259:Dopamine Agents; D037742:Nanotubes, Carbon; D013451:Sulfonic Acids; D014527:Uric Acid; C002502:2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid; D001205:Ascorbic Acid; D004298:Dopamine