title: Serum fetuin-A levels are associated with the presence and severity of coronary artery disease in patients with type 2 diabetes.
abstract: OBJECTIVE
  To clarify the correlation between serum fetuin-A levels and the presence and severity of coronary artery disease (CAD) in patients with type 2 diabetes (T2DM).
  
  
  METHODS
  A total of 241 consecutive patients with T2DM and 69 controls were recruited. Serum fetuin-A levels were analyzed by enzyme-linked immunosorbent assay. The presence and severity of CAD were evaluated by coronary angiography (CAG).
  
  
  RESULTS
  Serum fetuin-A levels are independently correlated with the presence and severity of CAD in T2DM patients.
  
  
  CONCLUSIONS
  Fetuin-A might serve as a potential biomarker for reflecting the development and progression of CAD in T2DM patients.
authors: Department of Cardiology, Union Hospital, Fujian Institute of Coronary Artery Disease, Fujian Medical University, Fuzhou, P. R. China.
authors: Zi-Wen
authors: ZW
authors: Zhao
authors: Chao-Gui
authors: CG
authors: Lin
authors: Ling-Zhen
authors: LZ
authors: Wu
authors: Yu-Kun
authors: YK
authors: Luo
authors: Lin
authors: L
authors: Fan
authors: Xian-Feng
authors: XF
authors: Dong
authors: Hong
authors: H
authors: Zheng
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure; D015992:Body Mass Index; D016022:Case-Control Studies; D003324:Coronary Artery Disease / Q000097:blood* / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012720:Severity of Illness Index; D014280:Triglycerides / Q000097:blood; D060749:alpha-2-HS-Glycoprotein / Q000032:analysis / Q000378:metabolism*
chemical_list: C556354:AHSG protein, human; D015415:Biomarkers; D008077:Lipoproteins, LDL; D014280:Triglycerides; D060749:alpha-2-HS-Glycoprotein