title: Precise endoscopic and pathologic features in a Crohn's disease case with two fistula-associated small bowel adenocarcinomas complicated by an anal canal adenocarcinoma.
abstract: The patient was a 40-year-old man who had suffered from Crohn's disease (CD) for 19 years and developed an intractable perianal fistula and two strictures in the small bowel. Dilatation of the two strictures using double-balloon endoscopy did not improve the subileus symptoms. An anal canal adenocarcinoma was also detected using double-balloon endoscopy. The ileum and rectoperianal area were partially resected, and a precise immunohistochemical pathologic assessment revealed that all three lesions were fistula-associated adenocarcinomas. Accumulating endoscopic findings of CD-associated cancer and precise pathologic diagnostic findings will help to establish a suitable surveillance method.
authors: Department of Gastroenterology, Osaka City University Graduate School of Medicine, Japan. mitsue-s@med.osaka-cu.ac.jp
authors: Mitsue
authors: M
authors: Sogawa
authors: Kenji
authors: K
authors: Watanabe
authors: Yutaro
authors: Y
authors: Egashira
authors: Kiyoshi
authors: K
authors: Maeda
authors: Kenichi
authors: K
authors: Morimoto
authors: Atsushi
authors: A
authors: Noguchi
authors: Noriko
authors: N
authors: Kamata
authors: Hirokazu
authors: H
authors: Yamagami
authors: Toshio
authors: T
authors: Watanabe
authors: Kazunari
authors: K
authors: Tominaga
authors: Yasuhiro
authors: Y
authors: Fujiwara
authors: Nobuhide
authors: N
authors: Oshitani
authors: Tetsuo
authors: T
authors: Arakawa
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology*; D000328:Adult; D001005:Anus Neoplasms / Q000150:complications* / Q000473:pathology*; D003424:Crohn Disease / Q000150:complications* / Q000473:pathology*; D016099:Endoscopy, Gastrointestinal; D006801:Humans; D007078:Ileal Neoplasms / Q000150:complications* / Q000473:pathology*; D007412:Intestinal Fistula / Q000150:complications* / Q000473:pathology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000150:complications* / Q000473:pathology*