title: Five new secondary metabolites from Monascus purpureus-fermented Hordeum vulgare and Sorghum bicolor.
abstract: Long grains of Hordeum vulgare and Sorghum bicolor were individually fermented with Monascus purpureus MTCC 369 under solid state fermentation. The aqueous extract of Monascus which fermented H. vulgare and S. bicolor was found to contain five different new metabolites. Silica gel column chromatography of the aqueous extract with a linear gradient of ethyl acetate, acetonitrile and carbon tetrachloride (v/v) yielded five new metabolites named benzopranyl capriate (9H-1-isoprenyl-benzopyran-5-isopropanoic acid-6-ol-6-n-decanoate), shorghumoic acid (n-octadec-8,11-dien-7α-ol-1-oic acid) and sorghumflavin A (2-n-butyloxo-6-β-hydroxy-7-β-isoprenyl ankaflavin) from Monascus-fermented S. bicolor, while hordeumflavin B (2-n-undecanyloxo-7-β-isoprenyl ankaflavin) and vulgaredilone (2-dodecanyl-7-β isopranyl monoscodilone) from Monascus-fermented H. vulgare.
authors: a Microbial and Pharmaceutical Biotechnology Laboratory, Faculty of Pharmacy, Centre for Advance Research in Pharmaceutical Sciences, Jamia Hamdard , New Delhi , India.
authors: Md Pravej
authors: MP
authors: Ansari
authors: Alka
authors: A
authors: Puri
authors: M
authors: M
authors: Ali
authors: Bibhu Prasad
authors: BP
authors: Panda
mesh_terms: D005285:Fermentation; D005415:Flavins / Q000737:chemistry / Q000302:isolation & purification*; D001467:Hordeum / Q000737:chemistry*; D015394:Molecular Structure; D032741:Monascus / Q000378:metabolism*; D010936:Plant Extracts / Q000032:analysis*; D012639:Seeds / Q000737:chemistry* / Q000378:metabolism; D045868:Sorghum / Q000737:chemistry*; D014867:Water
chemical_list: D005415:Flavins; D010936:Plant Extracts; D014867:Water