title: The influence of third-body particles on wear rate in unicondylar knee arthroplasty: a wear simulator study with bone and cement debris.
abstract: The reduced intraoperative visibility of minimally invasive implanted unicondylar knee arthroplasty makes it difficult to remove bone and cement debris, which have been reported on the surface of damaged and retrieved bearings. Therefore, the aim of this study was to analyze the influence of bone and cement particles on the wear rate of unicompartmental knee prostheses in vitro. Fixed bearing unicompartmental knee prostheses were tested using a knee-wear-simulator according to the ISO standard 14243-1:2002(E) for 5.0 million cycles. Afterwards bone debris (particle size 671 ± 262 μm) were added to the test fluid in a concentration of 5 g/l for 1.5 million cycles, followed by 1.5 million cycles blended with cement debris (particle size 644 ± 186 μm) in the same concentration. Wear rate, knee-kinematics and wear-pattern were analyzed. The wear rate reached 12.5 ± 1.0 mm³/million cycles in the running-in and decreased during the steady state phase to 4.4 ± 0.91 mm³/million cycles. Bone particles resulted in a wear rate of 3.0 ± 1.27 mm³/million cycles with no influence on the wear rate compared to the steady state phase. Cement particles, however, lead to a significantly higher wear rate (25.0 ± 16.93 mm³/million cycles) compared to the steady state phase. The careful removal of extruded cement debris during implantation may help in reducing wear rate. Bone debris are suggested to have less critical influence on the prostheses wear rate.
authors: Department of Orthopaedic Surgery, University Hospital of Munich-LMU, Campus Grosshadern, Marchioninistraße 15, 81377 Munich, Germany. christian.schroeder@med.uni-muenchen.de
authors: Christian
authors: C
authors: Schroeder
authors: Thomas M
authors: TM
authors: Grupp
authors: Bernhard
authors: B
authors: Fritz
authors: Christoph
authors: C
authors: Schilling
authors: Yan
authors: Y
authors: Chevalier
authors: Sandra
authors: S
authors: Utzschneider
authors: Volkmar
authors: V
authors: Jansson
mesh_terms: D019645:Arthroplasty, Replacement, Knee / Q000295:instrumentation*; D001696:Biomechanical Phenomena; D001843:Bone Cements / Q000737:chemistry*; D019544:Equipment Failure Analysis / Q000295:instrumentation* / Q000379:methods; D005547:Foreign Bodies / Q000473:pathology; D006801:Humans; D007720:Knee Prosthesis; D010316:Particle Size; D011475:Prosthesis Failure; D013499:Surface Properties; D013582:Synovial Fluid / Q000502:physiology
chemical_list: D001843:Bone Cements