title: Solubilization capacity of nonionic surfactant micelles exhibiting strong influence on export of intracellular pigments in Monascus fermentation.
abstract: In this study, perstractive fermentation of intracellular Monascus pigments in nonionic surfactant micelle aqueous solution had been studied. The permeability of cell membrane modified by nonionic surfactant might have influence on the rate of export of intracellular pigments into its extracellular broth while nearly no effect on the final extracellular pigment concentration. However, the solubilization of pigments in nonionic surfactant micelles strongly affected the final extracellular pigment concentration. The solubilization capacity of micelles depended on the kind of nonionic surfactant, the super-molecule assembly structure of nonionic surfactant in an aqueous solution, and the nonionic surfactant concentration. Elimination of pigment degradation by export of intracellular Monascus pigments and solubilizing them into nonionic surfactant micelles was also confirmed experimentally. Thus, nonionic surfactant micelle aqueous solution is potential for replacement of organic solvent for perstractive fermentation of intracellular product.
authors: School of Biological Science and Engineering, South China University of Technology, Guangzhou 510006, China.
authors: Biyu
authors: B
authors: Kang
authors: Xuehong
authors: X
authors: Zhang
authors: Zhenqiang
authors: Z
authors: Wu
authors: Hanshi
authors: H
authors: Qi
authors: Zhilong
authors: Z
authors: Wang
mesh_terms: D002463:Cell Membrane Permeability / Q000187:drug effects; D005285:Fermentation; D008823:Micelles; D032741:Monascus / Q000187:drug effects* / Q000378:metabolism*; D010860:Pigments, Biological / Q000378:metabolism*; D013501:Surface-Active Agents / Q000378:metabolism*
chemical_list: D008823:Micelles; D010860:Pigments, Biological; D013501:Surface-Active Agents