title: Multiple biological properties of macelignan and its pharmacological implications.
abstract: Macelignan found in the nutmeg mace of Myristica fragrans obtains increasing attention as a new avenue in treating various diseases. Macelignan has been shown to possess a spectrum of pharmacological activities, including anti-bacterial, anti-inflammatory, anti-cancer, anti-diabetes, and hepatoprotective activities; recently, it has also been shown to have neuroprotective activities. This review summarizes the current research on the biological effects of macelignan derived from M. fragrans, with emphasis on the importance in understanding and treating complex diseases such as cancer and Alzheimer's disease.
authors: Department of Biological Sciences, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul, 143-701, South Korea.
authors: Saswati
authors: S
authors: Paul
authors: Jae Kwan
authors: JK
authors: Hwang
authors: Hahn Young
authors: HY
authors: Kim
authors: Won Kyung
authors: WK
authors: Jeon
authors: ChiHye
authors: C
authors: Chung
authors: Jung-Soo
authors: JS
authors: Han
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects / Q000502:physiology; D006801:Humans; D017705:Lignans / Q000737:chemistry* / Q000494:pharmacology*; D026323:Myristica; D018696:Neuroprotective Agents / Q000737:chemistry / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D017705:Lignans; D018696:Neuroprotective Agents; D010936:Plant Extracts; C502026:macelignan