title: Incorporating graphene oxide and gold nanoclusters: a synergistic catalyst with surprisingly high peroxidase-like activity over a broad pH range and its application for cancer cell detection.
abstract: A synergistic graphene oxide-gold nanocluster (GO-AuNC) hybrid has been constructed as an enzyme mimic that is able to show high catalytic activity over a broad pH range, especially at neutral pH. Importantly, the target-functionalized hybrid has been applied as a robust nanoprobe for selective, quantitative, and fast colorimetric detection of cancer cells.
authors: State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Changchun, Jilin 130022, China.
authors: Yu
authors: Y
authors: Tao
authors: Youhui
authors: Y
authors: Lin
authors: Zhenzhen
authors: Z
authors: Huang
authors: Jinsong
authors: J
authors: Ren
authors: Xiaogang
authors: X
authors: Qu
mesh_terms: D000818:Animals; D040761:Biomimetic Materials / Q000737:chemistry*; D002151:Calorimetry; D002384:Catalysis; D045744:Cell Line, Tumor; D002469:Cell Separation / Q000379:methods*; D006046:Gold / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D053768:Metal Nanoparticles / Q000737:chemistry*; D051379:Mice; D008958:Models, Molecular; D008968:Molecular Conformation; D010087:Oxides / Q000737:chemistry*; D009195:Peroxidase / Q000378:metabolism*; D013997:Time Factors
chemical_list: D010087:Oxides; D006046:Gold; D006108:Graphite; D009195:Peroxidase