title: Neural pattern similarity predicts long-term fear memory.
abstract: Although certain changes in the brain may reflect fear learning, there are no known markers that indicate whether an aversive experience will develop into fear memory. We examined the moment-to-moment dynamics of human fear learning by applying multi-voxel pattern analysis to single-trial blood oxygen level-dependent magnetic resonance imaging data. We found that the long-term behavioral expression of fear memory could be predicted from neural patterns at the time of learning.
authors: Department of Clinical Psychology, University of Amsterdam, Amsterdam, The Netherlands.
authors: Renée M
authors: RM
authors: Visser
authors: H Steven
authors: HS
authors: Scholte
authors: Tinka
authors: T
authors: Beemsterboer
authors: Merel
authors: M
authors: Kindt
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000378:metabolism*; D005239:Fear / Q000502:physiology* / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D057567:Memory, Long-Term / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology; D010775:Photic Stimulation / Q000379:methods; D011237:Predictive Value of Tests; D011680:Pupil / Q000502:physiology; D055815:Young Adult