title: Targeting multiplicity: the key factor for anti-cancer nanoparticles.
abstract: In this mini-review, we focus on different strategies to bring nanotools specifically to cancer cells. We discuss about a better targeting of tumor, combining the characteristics of tumor environment, the increase in nanoparticles life time, the biomarkers overexpressed on cancer cells and different physical methods for non invasive therapies. Here we detail the necessity of a synergy between passive and active targeting for an actual specificity of cancer cells.
authors: Institut des Biomolecules Max Mousseron, UMR 5247 CNRS-UM1-UM2, 15 Avenue Charles Flahault, BP 14491, 34093 Montpellier Cedex 05, France.
authors: M
authors: M
authors: Gary-Bobo
authors: O
authors: O
authors: Vaillant
authors: M
authors: M
authors: Maynadier
authors: I
authors: I
authors: Basile
authors: A
authors: A
authors: Gallud
authors: K
authors: K
authors: El Cheikh
authors: E
authors: E
authors: Bouffard
authors: A
authors: A
authors: Morère
authors: X
authors: X
authors: Rébillard
authors: P
authors: P
authors: Puche
authors: P
authors: P
authors: Nirdé
authors: M
authors: M
authors: Garcia
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D053758:Nanoparticles / Q000032:analysis*; D009369:Neoplasms / Q000098:blood supply / Q000188:drug therapy* / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism; D059016:Tumor Microenvironment
chemical_list: D000970:Antineoplastic Agents; D010100:Oxygen