title: [The impact of tobacco smoking on the selected risk factors for cardiovascular disease in students of Poznan University of Medical Sciences].
abstract: The aim of this study was to assess the impact of tobacco smoking on the selected risk factors for cardiovascular disease in young adults.
  
  
  METHODS
  we analyzed the results of cardiovascular screening management on medical students aged 20-24. The study was conducted on 438 persons, 350 non-smokers (N) and 88 smokers (S) declared as healthy individuals: 274 females (F), 230 non-smokers (FN) and 44 smokers (FS), and 164 males (M), 120 non-smokers (MN) and 44 smokers (MS). The subjects were measured waist, body mass index (BMI), systolic (SBP) and diastolic (DBP) blood pressure, They were assessed fasting capillary blood tests: glucose, total cholesterol (T-C), triacylglycerols (TAG), HDL cholesterol (HDL-C), LDL cholesterol (LDL-C), nonHDL-C, T-C/HDL-C ratio, using analyzer Reflotron Plus (Roche Diagnostics, USA). The results collected in groups of females (F), males (M), non-smokers (N) and smokers (S) were calculated using Statistica 10 version.
  
  
  RESULTS
  Females and males did not differ with their age, BMI, TAG, LDL-C and nonHDL-C, but males presented physiological higher waist and T-C/HDL-C ratio, decreased HDL-C, and higher SBP and DBP, although within references. N and S females did not differ with waist, BMI, SBP and DBP, similar to N and S males. Smokers (S) presented increased TAG, decreased HDL-C and higher waist, comparing with non-smokers (N) - without relation of TAG and HDL-C to either waist or BMI. FS group were found increased TAG and correlation TAG&BMI (R=0,45), as compared with FN group. MS group had higher TAG and lower HDL-C than MN group, and negative correlation TAG&HDL-C (R=-0,39).
  
  
  CONCLUSIONS
  Tobacco smoking, an independent risk factor for cardiovascular disease, can modify plasma lipid profile in young adults to increase the risk more, especially in males.
authors: Zakład Biochemii Klinicznej i Medycyny Laboratoryjnej Katedry Chemii i Biochemii Klinicznej Uniwersytetu Medycznego im. K. Marcinkowskiego w Poznaniu. kmackowiak@ump.edu.pl
authors: Kalina
authors: K
authors: Maćkowiak
authors: Marcin
authors: M
authors: Nowicki
authors: Ewa
authors: E
authors: Wysocka
authors: Alicja
authors: A
authors: Brozek
authors: Lech
authors: L
authors: Torliński
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000378:metabolism*; D015984:Causality; D015897:Comorbidity; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D011044:Poland / Q000453:epidemiology; D012307:Risk Factors; D012727:Sex Characteristics; D017678:Sex Distribution; D012907:Smoking / Q000453:epidemiology* / Q000378:metabolism*; D013337:Students, Medical / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: D008055:Lipids