title: Sexual and reproductive health in a UK cohort of young adults perinatally infected with HIV.
abstract: OBJECTIVE
  To assess sexual health and behaviour outcomes of young adults with perinatally acquired HIV-1 (PaHIV), and audit sexual health interventions against published standards of care.
  
  
  METHODS
  Retrospective case note audit of 16-25-year-olds with PaHIV attending a dedicated transition clinic from January 2005 to 2011.
  
  
  RESULTS
  Fifty-two young adults, 31 women, median age 20 years. 41 were sexually active; median age of coitarche 16 years. Median number of lifetime partners was 3.5, and five reported non-consensual sex. All had a sexually transmitted infection (STI) screen; 6 were diagnosed with an STI, genital warts (human papilloma virus) most frequently. The median interval from coitarche to first STI screen was 2 years. The pregnancy incidence was 103 per 1000 person years. 18/25 (72%) sexually active women had a cervical smear, four had colposcopy. All patients had hepatitis B virus (HBV) serology. 47 had not been vaccinated against HBV prior to transition. 23 completed HBV vaccination of which 11 had surface antibody >100 IU/ml at 1 year.
  
  
  CONCLUSIONS
  The majority of our cohort was sexually active while still under the care of paediatric health services. Cervical screening and hepatitis B vaccination rates fell short of audit standards. Vaccination for hepatitis B should be considered prior to transfer of care to adult HIV services.
authors: Jefferiss Wing, St Mary’s Hospital, Imperial College Healthcare NHS Trust, London, UK. a.croucher@imperial.ac.uk
authors: Adam P
authors: AP
authors: Croucher
authors: Sophie
authors: S
authors: Jose
authors: Susan
authors: S
authors: McDonald
authors: Caroline
authors: C
authors: Foster
authors: Sarah
authors: S
authors: Fidler
mesh_terms: D000293:Adolescent; D016497:Adolescent Health Services; D000328:Adult; D005260:Female; D006679:HIV Seropositivity / Q000453:epidemiology*; D007722:Health Knowledge, Attitudes, Practice; D006509:Hepatitis B / Q000453:epidemiology* / Q000517:prevention & control*; D017325:Hepatitis B Vaccines / Q000008:administration & dosage; D006801:Humans; D008131:London / Q000453:epidemiology; D008297:Male; D010342:Patient Acceptance of Health Care; D060728:Reproductive Health / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D012725:Sexual Behavior / Q000523:psychology / Q000706:statistics & numerical data*; D012747:Sexual Partners; D060305:Transition to Adult Care; D055815:Young Adult
chemical_list: D017325:Hepatitis B Vaccines
keywords: ADOLESCENT; HEPATITIS B; HIV; PERINATAL INFECTION; SEXUAL HEALTH