title: Active surveillance for asymptomatic carriers of carbapenemase-producing Klebsiella pneumoniae in a hospital setting.
abstract: The spread of carbapenemase-producing Klebsiella pneumoniae (CPKP) is a challenging public health threat. Early identification and isolation of infected patients and carriers are key measures of control. This study describes a CPKP screening strategy in a tertiary Italian hospital. During the five-month study period, 1687 patients were screened by rectal swabs. Of these, 65 (3.9%) tested positive for CPKP; 5.1% of case contacts tested positive. Screening case contacts appears to be the essential surveillance component for detecting asymptomatic carriers of CPKP. The added value of selective CPKP screening on hospital admission depends on the frequency of carriers among incoming patients.
authors: Agenzia Sanitaria e Sociale Regionale Emilia-Romagna, Bologna, Italy. cgagliotti@regione.emilia-romagna.it
authors: C
authors: C
authors: Gagliotti
authors: V
authors: V
authors: Ciccarese
authors: M
authors: M
authors: Sarti
authors: S
authors: S
authors: Giordani
authors: A
authors: A
authors: Barozzi
authors: C
authors: C
authors: Braglia
authors: C
authors: C
authors: Gallerani
authors: R
authors: R
authors: Gargiulo
authors: G
authors: G
authors: Lenzotti
authors: O
authors: O
authors: Manzi
authors: D
authors: D
authors: Martella
authors: M L
authors: ML
authors: Moro
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism*; D002353:Carrier State / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D007558:Italy; D007710:Klebsiella Infections / Q000175:diagnosis* / Q000382:microbiology; D007711:Klebsiella pneumoniae / Q000201:enzymology / Q000302:isolation & purification*; D012007:Rectum / Q000382:microbiology; D018571:Sentinel Surveillance; D062606:Tertiary Care Centers; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase