title: Influence of racing on the serum concentrations of the cardiac biomarkers troponin I and creatine kinase myocardial band (CK-MB) in racing greyhounds.
abstract: The objective of this study was to investigate the effect of racing on the serum concentrations of cardiac troponin I (cTnI) and creatine kinase myocardial band (CK-MB) in 32 racing greyhounds. Blood samples were collected 24h prior to a 7 km race (T0), within 2h of completion of the race (T1), and 24h post-race (T2). Blood samples were also collected from 20 non-racing greyhounds. The median cTnI concentration in the racing greyhounds was not significantly different from that in the non-racing greyhounds (0.045 ng/mL). Before racing, the median cTnI concentration in the racing greyhounds was 0.050 ng/mL. Following the 7 km race, 31/32 greyhounds showed increases in cTnI concentrations which were significantly higher than the pre-race concentrations (P<0.0001). cTnI concentrations dropped back 24h post-race to values not significantly different from the pre-race concentrations. Following the race, 5/32 greyhounds showed mild increases in CK-MB concentrations but these were not significantly different from the pre-race values. These findings could be of importance when evaluating greyhounds with suspected cardiac disease that have recently performed hard exercise.
authors: Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, Qassim University, Saudi Arabia.
authors: Mohamed
authors: M
authors: Tharwat
authors: Fahd
authors: F
authors: Al-Sobayil
authors: Sébastien
authors: S
authors: Buczinski
mesh_terms: D000818:Animals; D015415:Biomarkers; D003402:Creatine Kinase / Q000097:blood* / Q000378:metabolism; D004285:Dogs / Q000097:blood* / Q000502:physiology*; D010805:Physical Conditioning, Animal; D012420:Running; D013177:Sports; D019210:Troponin I / Q000097:blood* / Q000378:metabolism
chemical_list: D015415:Biomarkers; D019210:Troponin I; D003402:Creatine Kinase
keywords: Cardiac biomarkers; Cardiac troponin I (cTnI); Creatine kinase myocardial band (CK-MB); Greyhounds; Racing dog