title: The relationship between nut consumption and lipid profile among the Iranian adult population; Isfahan Healthy Heart Program.
abstract: OBJECTIVE
  The study was carried out to assess the relationship between nut consumption and lipid profile among Iranian adults.
  
  
  METHODS
  The study was based on data from the Isfahan Healthy Heart Program across three counties in central Iran in 2007. A cross-sectional survey of 9660 randomly selected adults aged ≥ 19 years were chosen based on sex, age and settlement distributions in each community. Nutritional behaviors were assessed by validated qualitative 48-item food frequency questionnaires, which covered regular intakes of four types of nuts: walnuts, almonds, pistachios and hazelnuts. Analysis of covariance and logistic regression tests were utilized to determine odds ratio (OR) 95% confidence interval of hyperlipidemia according to nut consumption patterns in unadjusted and three-adjusted models.
  
  
  RESULTS
  The results showed a significant link between high nut consumption and lower total cholesterol, triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) levels and apo B/apo A ratio (P<0.05) in female subjects and lower TG, LDL-C and apoB/apoA ratio in male subjects (P<0.05). The frequency of nut consumption was inversely associated with dyslipidemia, especially for those who had consumed nuts ≥ 4 times weekly (0.67 (0.57-0.79)). After adjusting for sex, age and other potential confounders, ORs increased enormously. Except for low apo A and high LDL-C, more frequent nut consumption (4 ≤ times per week) had a significant inverse effect on other dyslipidemia risk factors in all four models.
  
  
  CONCLUSIONS
  We concluded that frequent consumption of nuts, particularly ≥ 4 times a week, may result in lower dyslipidemia occurrences and may exert cardioprotective effects.
authors: Nutrition Faculty, Isfahan University of Medical Sciences, Isfahan, Iran.
authors: G
authors: G
authors: Askari
authors: N
authors: N
authors: Yazdekhasti
authors: N
authors: N
authors: Mohammadifard
authors: N
authors: N
authors: Sarrafzadegan
authors: A
authors: A
authors: Bahonar
authors: M
authors: M
authors: Badiei
authors: F
authors: F
authors: Sajjadi
authors: M
authors: M
authors: Taheri
mesh_terms: D000328:Adult; D000368:Aged; D001054:Apolipoproteins A / Q000097:blood; D001055:Apolipoproteins B / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood*; D003430:Cross-Sectional Studies; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood; D007492:Iran; D008077:Lipoproteins, LDL / Q000097:blood*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D009754:Nuts; D016017:Odds Ratio; D012307:Risk Factors; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D014280:Triglycerides / Q000097:blood*; D044465:White People; D055815:Young Adult
chemical_list: D001054:Apolipoproteins A; D001055:Apolipoproteins B; D008076:Cholesterol, HDL; D008077:Lipoproteins, LDL; D014280:Triglycerides