title: Cytokinesis: centralspindlin moonlights as a membrane anchor.
abstract: The hardest working complex in animal cell division has a new gig. This extraordinary machine, the centralspindlin complex, works overtime, contributing to nearly every step in cytokinesis. It has now been shown to stabilize an association between the plasma membrane and the midbody microtubules prior to abscission.
authors: Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL 60637, USA. mglotzer@uchicago.edu
authors: Michael
authors: M
authors: Glotzer
mesh_terms: D002455:Cell Division; D002462:Cell Membrane / Q000378:metabolism*; D048749:Cytokinesis / Q000502:physiology*; D020690:GTPase-Activating Proteins / Q000378:metabolism*; D006801:Humans; D008869:Microtubule-Associated Proteins / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism; D017434:Protein Structure, Tertiary; D008941:Spindle Apparatus / Q000378:metabolism*
chemical_list: D020690:GTPase-Activating Proteins; D008869:Microtubule-Associated Proteins; C115995:mgcRacGAP