title: A systematic review of health care interventions for pain in patients with advanced cancer.
abstract: OBJECTIVE
  Poorly controlled pain is common in advanced cancer. The objective of this article was to synthesize the evidence on the effectiveness of pain-focused interventions in this population.
  
  
  METHODS
  We searched MEDLINE, CINAHL, PsycINFO, Cochrane, and DARE from 2000 through December 2011. We included prospective, controlled health care intervention studies in advanced cancer populations, focusing on pain.
  
  
  RESULTS
  Nineteen studies met the inclusion criteria; most focused on nurse-led patient-centered interventions. In all, 9 (47%) of the 19 studies found a significant effect on pain. The most common intervention type was patient/caregiver education, in 17 (89%) of 19 studies, 7 of which demonstrated a significant decrease in pain.
  
  
  CONCLUSIONS
  We found moderate strength of evidence that pain in advanced cancer can be improved using health care interventions, particularly nurse-led patient-centered interventions.
authors: 1Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
authors: Kathryn A
authors: KA
authors: Martinez
authors: Rebecca A
authors: RA
authors: Aslakson
authors: Renee F
authors: RF
authors: Wilson
authors: Colleen C
authors: CC
authors: Apostol
authors: Oluwakemi A
authors: OA
authors: Fawole
authors: Brandyn D
authors: BD
authors: Lau
authors: Daniela
authors: D
authors: Vollenweider
authors: Eric B
authors: EB
authors: Bass
authors: Sydney M
authors: SM
authors: Dy
mesh_terms: D002986:Clinical Trials as Topic; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D010146:Pain / Q000209:etiology*; D059408:Pain Management / Q000379:methods*; D010166:Palliative Care / Q000379:methods*; D010353:Patient Education as Topic; D017060:Patient Satisfaction; D012720:Severity of Illness Index
keywords: advanced cancer; end of life; health care interventions; pain; quality improvement; systematic review