title: Evaluation of one- vs. two-layered closure after wedge excision of 43 eyelid tumors in dogs.
abstract: OBJECTIVE
  The aim was to evaluate how two closure techniques after full-thickness V-shaped excision relate to wound recovery and how these techniques affect eyelid function and stability of the preocular tear film.
  
  
  METHODS
  Thirty-eight dogs with 43 eyelid tumors involving <25% of eyelid margin length were included in a prospective randomized trial.
  
  
  METHODS
  The method for wound closure was chosen randomly before the operation. In group A (n = 20), the wound was closed in one layer and in group B (n = 23) in two layers. The wound and eyelid structure were directly evaluated by slit-lamp biomicroscopy several times postoperatively. Eyelid function was indirectly evaluated by interferometry, noninvasive tear film breakup time (nTFBUT), and Schirmer's tear test at the last examination, 5 weeks to 19 months postoperatively.
  
  
  RESULTS
  No significant differences were found in group A vs. B although slightly more cases with perfect alignment of the eyelid were seen in group B. In both groups, neither slit-lamp biomicroscopy, interferometry, nTFBUT, nor Schirmer's tear test revealed negative influence on the eyelid function by the previous surgery. Histologically, 29 of 32 tumors were diagnosed as meibomian gland adenomas.
  
  
  CONCLUSIONS
  These results do not demonstrate a significant difference in wound recovery, eyelid structure, and function after wound closure in 1 vs. 2 layers.
authors: Small Animal Clinic, Faculty of Veterinary Medicine, Freie Universität Berlin, Oertzenweg 19b, D-14163, Berlin, Germany.
authors: Gwendolyna
authors: G
authors: Romkes
authors: Robert
authors: R
authors: Klopfleisch
authors: Johanna Corinna
authors: JC
authors: Eule
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000601:surgery*; D004285:Dogs; D005142:Eyelid Neoplasms / Q000601:surgery / Q000662:veterinary*; D005143:Eyelids / Q000601:surgery; D005260:Female; D008297:Male; D013536:Suture Techniques / Q000662:veterinary*
keywords: eyelid function; eyelid wound closure; interferometry; meibomian gland adenoma; noninvasive tear film breakup time