title: Use of oxidized and regenerated cellulose polymer in oncoplastic breast surgery.
abstract: OBJECTIVE
  The aim of this paper is evaluate the use of oxidized regenerated cellulose in order to control breast symmetry, shape and volume reducing skin retraction after wide excision for the treatment of early breast cancer.
  
  
  METHODS
  The Authors describe a new procedure using oxidized regenerated cellulose polymer after 8 resections for breast cancer and 1 total galactophore ducts resection for nipple discharge.
  
  
  CONCLUSIONS
  Oncoplastic breast surgery allows a more radical local tumour excision achieving an acceptable cosmetic result. Breast reshaping absorbs the volume loss and decreases the risk of a localized defect although there are zones that are at high risk of deformity. Once reabsorption of the seroma occurs, the excision cavity becomes prominent due to fibrosis and retraction of the surrounding tissue creating a noticeable defect.
  
  
  CONCLUSIONS
  In oncoplastic breast surgery the oxidized regenerated cellulose by preventing the hematoma, can promote dermal fibroblasts proliferation and cell migration playing a role in adjustment of the shape, volume and symmetry of the breast and reducing skin retraction.
authors: Pier Carlo
authors: PC
authors: Rassu
authors: Alberto
authors: A
authors: Serventi
authors: Eliana
authors: E
authors: Giaminardi
authors: Ilaria
authors: I
authors: Ferrero
authors: Paolo
authors: P
authors: Tava
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000601:surgery*; D002483:Cellulose, Oxidized / Q000627:therapeutic use*; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D016462:Mammaplasty / Q000379:methods*; D008408:Mastectomy; D008875:Middle Aged; D011108:Polymers
chemical_list: D002483:Cellulose, Oxidized; D006490:Hemostatics; D011108:Polymers