title: Acute generalized exanthematous pustulosis associated with terbinafine: a case report.
abstract: A 27-year-old male patient who has used oral terbinafine for two weeks was admitted to our outpatient clinic for non-follicular millimetric pustules on erythematous and edematous different-sized plaques on his trunk and flexural areas. He was diagnosed with acute generalized exanthematous pustulosis (AGEP) because of terbinafine use in the light of history, clinical and histopathological findings. An AGEP is a rare and severe pustular reaction usually triggered by systemic drug intake. Approximately, 2.3% of the patients having oral terbinafine have been reported to develop cutaneous adverse effects. Although terbinafine is a commonly used medicine, it must be considered that it may cause severe adverse reactions.
authors: Department of Dermatology, Medical Faculty, Duzce University, Konuralp, Duzce, Turkey. drhakanturan@gmail.com
authors: Hakan
authors: H
authors: Turan
authors: Ersoy
authors: E
authors: Acer
authors: Havva
authors: H
authors: Erdem
authors: Esma
authors: E
authors: Uslu
authors: Cihangir
authors: C
authors: Aliagaoglu
mesh_terms: D056150:Acute Generalized Exanthematous Pustulosis / Q000209:etiology* / Q000473:pathology; D000328:Adult; D000935:Antifungal Agents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009092:Mucous Membrane / Q000473:pathology; D009281:Naphthalenes / Q000009:adverse effects*; D012867:Skin / Q000473:pathology; D000077291:Terbinafine
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine