title: Pediatric primitive intraneural synovial sarcoma of L-5 nerve root.
abstract: Primitive intraneural synovial sarcomas are rare in children. The authors report the case of a 7-year-old girl affected by intraneural synovial sarcoma of a lumbar nerve root, the first such lesion in this location described in a child. The lesion mimicked a schwannoma clinically and radiologically. There was long-lasting leg pain in a radicular distribution, and a well-demarcated intraneural tumor was seen on MRI. On this basis, the first resection was conservative. However, histological examination documented a classic biphasic synovial sarcoma, which was confirmed by immunohistochemistry. After radical resection and adjuvant treatment, complete disease control was achieved and verified at 5-year follow-up. This case strongly suggests that early diagnosis and a multidisciplinary approach to this unusual spinal lesion are essential to achieving a better prognosis.
authors: Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico Carlo Besta, Via Celoria 11, 20133 Milano, Italy.
authors: Francesco
authors: F
authors: Peia
authors: Marco
authors: M
authors: Gessi
authors: Paola
authors: P
authors: Collini
authors: Andrea
authors: A
authors: Ferrari
authors: Alessandra
authors: A
authors: Erbetta
authors: Laura G
authors: LG
authors: Valentini
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D013584:Sarcoma, Synovial / Q000175:diagnosis* / Q000628:therapy*; D013126:Spinal Nerve Roots