title: [Dealing with massive bleeding and associated perioperative coagulopathy: recommendations for action of the German Society of Anaesthesiology and Intensive Care Medicine].
abstract: Massive bleeding with coagulopathy and hemorrhagic shock poses a potential threat to life in numerous clinical settings. Optimal treatment including the prevention of exsanguination necessitates a standardized and interdisciplinary approach. Several studies have shown the importance of massive transfusion protocols and standardized coagulation algorithms to improve survival of severely bleeding patients and to avoid secondary complications. Thus, the Helsinki declaration for patient safety in anesthesiology demands the implementation of clinical practice guidelines for the treatment of patients requiring massive transfusion. This paper introduces a standardized algorithm for the treatment of patients with massive bleeding which was developed in consensus with the German Society of Anaesthesiology and Intensive Care Medicine (DGAI).
authors: Klinik für Anästhesiologie, Universitätsklinikum Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland. ogrottke@ukaachen.de
authors: O
authors: O
authors: Grottke
authors: T
authors: T
authors: Frietsch
authors: M
authors: M
authors: Maas
authors: H
authors: H
authors: Lier
authors: R
authors: R
authors: Rossaint
mesh_terms: D000465:Algorithms; D000925:Anticoagulants / Q000627:therapeutic use; D000933:Antifibrinolytic Agents / Q000627:therapeutic use; D001778:Blood Coagulation Disorders / Q000209:etiology / Q000628:therapy*; D001803:Blood Transfusion; D005858:Germany; D017408:Guidelines as Topic; D006381:Helsinki Declaration; D006470:Hemorrhage / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D006487:Hemostasis; D006801:Humans; D007431:Intraoperative Complications / Q000628:therapy*; D008991:Monitoring, Physiologic; D061214:Patient Safety; D059035:Perioperative Period; D010952:Plasma Substitutes / Q000627:therapeutic use; D012771:Shock, Hemorrhagic / Q000209:etiology / Q000628:therapy; D013534:Survival
chemical_list: D000925:Anticoagulants; D000933:Antifibrinolytic Agents; D010952:Plasma Substitutes