title: Canine oral fibrosarcomas: a retrospective analysis of 65 cases (1998-2010).
abstract: The objective of this retrospective study was to report the outcome of treatment of canine oral fibrosarcomas (FSA) in relation to median survival and progression-free survival (PFS), and to report whether grade was prognostic in relation to median survival. Sixty-five dogs with oral FSA presented to the WSU VTH between June 1998 and March 2010. Significant predictors of median survival were location (P = 0.0099), tumour size or oral stage (P = 0.0312), type of surgery (P = 0.0182), margins (P = 0.0329) and grade (P = 0.0251). Significant predictors of PFS were location (P = 0.0177), and radiation protocol (P = 0.0343). A combination of surgery and radiation was the strongest predictor of prolonged median survival (P = 0.0183) and PFS (P = 0.0263) at 505 and 301 days, respectively. Treatment of canine oral FSA with a combination of surgery and radiation therapy provided the longest median survivals.
authors: Department of Small Animal Clinical Sciences, University of Florida, Gainsville, FL, USA.
authors: H
authors: H
authors: Gardner
authors: J
authors: J
authors: Fidel
authors: G
authors: G
authors: Haldorson
authors: W
authors: W
authors: Dernell
authors: B
authors: B
authors: Wheeler
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000532:radiotherapy / Q000601:surgery*; D004285:Dogs; D005260:Female; D005354:Fibrosarcoma / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D008297:Male; D009062:Mouth Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: dogs; oral fibrosarcoma; radiation therapy; surgery