title: Sugammadex.
abstract: Sugammadex is the first selective antagonist to reverse neuromuscular blockade induced by rocuronium and vecuronium. The mechanism by which sugammadex works is superior to current neuromuscular block reversal strategies in terms of speed, efficacy and side effects. There is little contemporary guidance on the use of sugammadex in intensive care medicine. This review covers the key pharmacological features, clinical uses and cost- effectiveness in the context of intensive care practice.
authors: Austin Health, Melbourne, VIC, Australia. dharshi.karalapillai@austin.org.au
authors: Dharshi
authors: D
authors: Karalapillai
authors: Melissa
authors: M
authors: Kaufman
authors: Laurence
authors: L
authors: Weinberg
mesh_terms: D006801:Humans; D000077122:Sugammadex; D047408:gamma-Cyclodextrins / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D047408:gamma-Cyclodextrins; D000077122:Sugammadex