title: Small bowel tumors discovered during double-balloon enteroscopy: analysis of a large prospectively collected single-center database.
abstract: BACKGROUND
  The emergence of capsule endoscopy and double-balloon enteroscopy (DBE) has greatly enhanced the management of small bowel tumors (SBTs). DBE is particularly useful as a diagnostic modality because it allows for direct investigation of the gastrointestinal lumen, yet little data exist regarding its clinical efficacy.
  
  
  OBJECTIVE
  : To determine the diagnostic yield of DBE in detection of SBTs.
  
  
  METHODS
  We restrospectively reviewed our large prospectively collected DBE database from September 2005 to May 2012. Patients who were diagnosed with SBTs by DBE were included in the study. The diagnostic yield of DBE in detection of SBTs was calculated by frequency analysis.
  
  
  RESULTS
  A total of 1106 patients underwent 1652 DBE procedures. Of these patients, 134 (12.1%) were found to have an SBT. The majority (56.7%) of patients diagnosed with SBT were male, and the average age at the time of diagnosis was 64 years (SD±14 y). Indications for performing DBE included suspected mass lesion in 54.5% (73/134) of SBT patients, obscure gastrointestinal bleeding in 26.9% (36/134), and overt gastrointestinal bleeding in 14.9% (20/134). The most common SBTs identified were: carcinoid (26/134, 19.4%), hamartoma (14/134, 10.4%), inflammatory polyp (11/134, 8.2%), gastrointestinal stromal tumor (10/134, 7.5%), and lymphoma (10/134, 7.5%).
  
  
  CONCLUSIONS
  DBE is a valuable tool in the evaluation of SBTs. The incidence of SBTs in our patient population was significantly higher than the generally accepted incidence for the overall population, but was comparable with other similar studies. Carcinoid tumor was the most common SBT identified, and was most often seen in the ileum.
authors: Departments of *Internal Medicine †Gastroenterology & Hepatology, Mayo Clinic, Jacksonville, FL.
authors: David J
authors: DJ
authors: Cangemi
authors: Mihir K
authors: MK
authors: Patel
authors: Victoria
authors: V
authors: Gomez
authors: John R
authors: JR
authors: Cangemi
authors: Mark E
authors: ME
authors: Stark
authors: Frank J
authors: FJ
authors: Lukens
mesh_terms: D000368:Aged; D002276:Carcinoid Tumor / Q000175:diagnosis / Q000473:pathology; D016208:Databases, Factual; D058582:Double-Balloon Enteroscopy / Q000379:methods*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D015994:Incidence; D007414:Intestinal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies