title: [Minute granular lesions of the retinal pigment epithelium related to choroidal hyperpermeability in patients with central serous chorioretinopathy].
abstract: OBJECTIVE
  To investigate the relationship between increased permeability of choroidal vessels revealed by indocyanine green angiography (ICGA) and lesions of retinal pigment epithelium (RPE) revealed by Retro-mode (RM) in the eyes of patients with central serous chorioretinopathy (CSC).
  
  
  METHODS
  A retrospective cross-sectional study.
  
  
  METHODS
  We examined the minute granular lesions (MGLs) of the RPE using RM imaging (scanning laser ophthalmoscopy), in relation to the choroidal hyperpermeability visualized by indocyanine green angiography (ICGA) in 40 eyes of 20 Japanese patients with CSC. We classified them into two groups: eyes (25 eyes) with various retinal lesions and eyes without retinal lesions (15 eyes).
  
  
  RESULTS
  MGLs of the RPE in RM imaging were seen in 38 of 40 eyes (95%). The MGLs were detected in all 25 eyes in the group of various retinal lesions, and in 13 of 15 eyes (87%)in the group without retinal lesions. The area of MGLs exceeded the choroidal hyperpermeability in 18 eyes (45%), was the same as choroidal hyperpermeability in 15 eyes (38%), while 7 eyes (17%) had no hyperpermeability.
  
  
  CONCLUSIONS
  Choroidal hyperpermeability may be a possible cause of MGLs in the eyes of patients with CSC.
authors: Souen Muneyasu Eye Clinic, Japan. takedamnjp@ybb.ne.jp
authors: Muneyasu
authors: M
authors: Takeda
authors: Yui
authors: Y
authors: Sato
mesh_terms: D000328:Adult; D002199:Capillary Permeability / Q000502:physiology*; D056833:Central Serous Chorioretinopathy / Q000473:pathology* / Q000503:physiopathology; D002829:Choroid / Q000473:pathology* / Q000503:physiopathology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012189:Retrospective Studies