title: [Determination of insecticide-resistance and resistance mechanisms of Blattella germanica (Dictyoptera: Blattellidae)].
abstract: In this paper, the level of resistance to four insecticides of 3 Blatella germanica strains collected from various places in the City of Havana province was evaluated. These strains were resistant to two pyrethroids (cypermethrin and lambda-cyalothrine) and to organophosphorate malathion but susceptible to carbamate propoxur. The values of alpha and beta esterases, acetylcholinesterase and gluthatione-S-transferase were estimated in three strains involved in the study. The results of the study showed high esterase activity in all the strains, mainly beta esterases and two of the three strains presented with high gluthation-S-transferase enzyme. No changes in acetylcholinesterase were demonstrated in relation to the reference strain. The association of levels of resistance to insecticides, the possible resistance mechanisms in each strain and the results of the enzymatic activity were also analyzed.
authors: Instituto De Medicina Tropical Pedro Kouri. cristina.diaz@infomed.sld.cu
authors: Pantoja Cristina
authors: PC
authors: Díaz
authors: Yudelmis
authors: Y
authors: Alvarez Gavilán
authors: Yaxsier
authors: Y
authors: de Armas Rodríguez
authors: Juan A
authors: JA
authors: Bisset Lazcano
mesh_terms: D000287:Administration, Topical; D000818:Animals; D020048:Blattellidae / Q000187:drug effects* / Q000201:enzymology / Q000502:physiology; D004790:Enzyme Induction; D004950:Esterases / Q000502:physiology; D005982:Glutathione Transferase / Q000502:physiology; D008658:Inactivation, Metabolic; D019476:Insect Proteins / Q000502:physiology*; D007305:Insecticide Resistance / Q000502:physiology; D007306:Insecticides / Q000008:administration & dosage / Q000493:pharmacokinetics*; D008294:Malathion / Q000008:administration & dosage / Q000493:pharmacokinetics; D008297:Male; D009570:Nitriles / Q000008:administration & dosage / Q000493:pharmacokinetics; D001074:Propoxur / Q000008:administration & dosage / Q000493:pharmacokinetics; D011722:Pyrethrins / Q000008:administration & dosage / Q000493:pharmacokinetics
chemical_list: D019476:Insect Proteins; D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; C017160:cypermethrin; D001074:Propoxur; D005982:Glutathione Transferase; D004950:Esterases; D008294:Malathion; C037304:cyhalothrin