title: Systemic blood pressure after stent management for arch coarctation implications for clinical care.
abstract: OBJECTIVE
  The goal of this study was to prospectively assess blood pressure (BP) and echocardiographic parameters to delineate the incidence and nature of the hypertension burden in this cohort.
  
  
  BACKGROUND
  Few data are available on the long-term outcomes of aortic stenting.
  
  
  METHODS
  Thirty-one patients with successfully stented coarctation during childhood (mean age 12.4 years) underwent 24-h ambulatory BP monitoring (ABPM), exercise BP measurement, and echocardiographic assessment.
  
  
  RESULTS
  Mean time after stent implantation was 5.3 ± 4 years. Hypertension was noted on one-off right-arm BP assessment in 3 patients (10%), but on the basis of the 24-h ABPM assessment in 14 patients (45%). Twenty-four of 31 patients (80%) had an abnormally elevated exercise BP response. Peak exercise BP correlated with left ventricular mass index (r = 0.51; p < 0.05), which was also significantly increased in the entire cohort (mean = 91.3 g/m(2); p < 0.05). In patients with significant somatic growth since implantation, the indexed diameter of the stent (to aortic diameter) had significantly decreased from the 48th percentile at the implantation to the 4th percentile during the study (p < 0.05). There was no difference in any parameter between patients with native or those with recurrent coarctation.
  
  
  CONCLUSIONS
  Hypertension is endemic in patients with stented coarctation, irrespective of the absence of residual obstruction. Due to abnormal BP homeostasis, hypertension should be aggressively pursued by ABPM assessment and exercise stress testing in this population. Relative hypoplasia of the stented arch after somatic growth may contribute to this tendency and should provoke consideration of elective serial redilation of coarctation stents.
authors: Department of Pediatrics, Division of Cardiology, the Labatt Family Heart Center, the Hospital for Sick Children, the University of Toronto School of Medicine, Toronto, Ontario, Canada.
authors: Gareth J
authors: GJ
authors: Morgan
authors: Kyong Jin
authors: KJ
authors: Lee
authors: Rajiv
authors: R
authors: Chaturvedi
authors: Timothy J
authors: TJ
authors: Bradley
authors: Luc
authors: L
authors: Mertens
authors: Lee
authors: L
authors: Benson
mesh_terms: D000293:Adolescent; D000328:Adult; D001017:Aortic Coarctation / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D001794:Blood Pressure; D018660:Blood Pressure Monitoring, Ambulatory; D002648:Child; D004452:Echocardiography; D057510:Endovascular Procedures / Q000009:adverse effects / Q000295:instrumentation*; D005080:Exercise Test; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology*; D015994:Incidence; D008297:Male; D009864:Ontario / Q000453:epidemiology; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012008:Recurrence; D012307:Risk Factors; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult