title: Optimization of soluble organic selenium accumulation during fermentation of Flammulina velutipes mycelia.
abstract: Selenium is an essential nutrient with diverse physiological functions, and soluble organic selenium (SOS) sources have a higher bioavailability than inorganic selenium sources. Based on the response surface methodology and central composite design, this study presents the optimal medium components for SOS accumulation in batch cultures of Flammulina velutipes, i.e. 30 g/L glucose, 11.2 mg/L sodium selenite, and 1.85 g/L NH4NO3. Furthermore, logistic function model feeding was found to be the optimal feeding strategy for SOS accumulation during Flammulina velutipes mycelia fermentation, where the maximum SOS accumulation reached (4.63 +/- 0.24) mg/L, which is consistent with the predicted value.
authors: College of Life Science, Henan University, Kaifeng, 475004, China.
authors: Yunfeng
authors: Y
authors: Ma
authors: Fu
authors: F
authors: Xiang
authors: Jun
authors: J
authors: Xiang
authors: Longjiang
authors: L
authors: Yu
mesh_terms: D005285:Fermentation; D055393:Flammulina / Q000378:metabolism*; D025282:Mycelium / Q000378:metabolism*; D009930:Organic Chemicals / Q000378:metabolism*; D012643:Selenium / Q000378:metabolism*
chemical_list: D009930:Organic Chemicals; D012643:Selenium