title: [Diagnosis and treatment of the epithelial ovarian cancer at the West African Cancer Center of Dakar].
abstract: BACKGROUND
  Epithelial ovarian cancer are the most frequent of ovarian cancer, their prognosis is very bad. The aim of this study is to describe the diagnosis, the treatment and to assess the survival rate of the patients.
  
  
  METHODS
  It was a retrospective study realized at the Cancer Institute of Dakar from December 2000 to January 2007. We have collected 117 patients with epithelial ovarian cancer. The mean age was 49 years. Patients were comprised: 22 stage I, 32 stage II, 35 stage III and 26 stage IV. Primary surgery was performed to 34 patients and the other patients were treated with chemotherapy and surgery. The survival rate was assessed by Kaplan-Meier method and the Logrank test had allowed to compare the survival among age and optimal surgery.
  
  
  RESULTS
  Optimal surgery R0 was done in 20 cases and surgical resection R2 was performed in 45 cases. Pathological exam had found 65 serous cystadenocarcinoma, 28 mucinous cystadenocarcinoma and 21 endometrioid cystadenocarcinoma, one malignant tumor of Brenner. Overall survival at five years was 13.3%. The survival among optimal surgery was 16.3 and 2.3% for suboptimal surgery. There was no significant difference of the survival among patients who were less than 40 years old (P = 0.334).
  
  
  CONCLUSIONS
  Prognosis of epithelial ovarian cancer is worse in Senegal as like as in the world. To improve the survival of our patients, we must detect the early diagnosis of these tumors and to introduce the neoadjuvant chemotherapy before optimal surgery.
authors: Université Cheikh Anta Diop de Dakar-Sénégal, Institut du Cancer, 6604 Dakar-Étoile, Sénégal. adem@refer.sn
authors: Ahmadou
authors: A
authors: Dem
authors: Mamadou Moustapha
authors: MM
authors: Dieng
authors: Sidy
authors: S
authors: Ka
authors: Pape Macoumba
authors: PM
authors: Gaye
authors: Doudou
authors: D
authors: Diouf
authors: Mame Coumba
authors: MC
authors: Gaye-Fall
mesh_terms: D000328:Adult; D001948:Brenner Tumor / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D002277:Carcinoma / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D018269:Carcinoma, Endometrioid / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D018282:Cystadenocarcinoma, Mucinous / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D018284:Cystadenocarcinoma, Serous / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology / Q000628:therapy*; D012189:Retrospective Studies; D012675:Senegal / Q000453:epidemiology; D016019:Survival Analysis; D015996:Survival Rate
keywords: epithelial ovarian cancer; neoadjuvant chemotherapy; optimal surgery