title: Synthesis and characterization of a molecularly imprinted polymer for the determination of trace tributyltin in seawater and seafood by liquid chromatography-tandem mass spectroscopy.
abstract: Analysis of tributyltin chloride (TBT) in environmental samples, such as seawater, is important in order to evaluate the TBT contamination and accumulation in the trophic chain. The environmental impact of organotin compounds has been a particular focus of analytical studies. The present study reports the use of molecular imprinting technology coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) to determine trace amounts of TBT in seawater and seafood (mussel tissue samples). The imprinted polymer was synthesized by a non-covalent free-radical approach using acrylamide (AM) as a monomer and TBT as a template molecule in acetonitrile solvent (polymerization media). The imprinted polymer synthesized by this approach exhibited good adsorptive capacity and allowed specific retention of TBT. Recoveries of TBT in seawater samples spiked with different TBT concentrations ranged from 67.2% to 81.1% with peak area precision (RSD)<3.7%, and recoveries of TBT in mussel tissue samples ranged from 75.0% to 94.2% with RSD<4.8%.
authors: Faculty of Marine Science, Ningbo University, China.
authors: Shanshan
authors: S
authors: Zhu
authors: Futao
authors: F
authors: Hu
authors: Ting
authors: T
authors: Yang
authors: Ning
authors: N
authors: Gan
authors: Daodong
authors: D
authors: Pan
authors: Yuting
authors: Y
authors: Cao
authors: Dazhen
authors: D
authors: Wu
mesh_terms: D000327:Adsorption; D000818:Animals; D049872:Bivalvia / Q000737:chemistry*; D002853:Chromatography, Liquid / Q000379:methods; D004784:Environmental Monitoring / Q000379:methods*; D057230:Limit of Detection; D054802:Molecular Imprinting / Q000379:methods; D011108:Polymers / Q000737:chemistry; D017747:Seafood / Q000032:analysis*; D012623:Seawater / Q000032:analysis*; D052616:Solid Phase Extraction / Q000379:methods; D053719:Tandem Mass Spectrometry / Q000379:methods; D014220:Trialkyltin Compounds / Q000302:isolation & purification*; D014874:Water Pollutants, Chemical / Q000302:isolation & purification*
chemical_list: D011108:Polymers; D014220:Trialkyltin Compounds; D014874:Water Pollutants, Chemical; C011559:tributyltin