title: Highly diastereo- and enantioselective cross-cascade reactions of different enones.
abstract: Cascading ketones! The first highly efficient asymmetric cross-cascade reaction of different α,β-unsaturated ketones catalyzed by an easily prepared bulky primary amine salt has been developed. It affords the corresponding diverse products containing three to four contiguous stereocenters with excellent enantio- and diastereoselectivities (see scheme).
authors: Engineering Research Centre of Pharmaceutical Process Chemistry, Ministry of Education, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, PR China.
authors: Huicai
authors: H
authors: Huang
authors: Wenbin
authors: W
authors: Wu
authors: Kailong
authors: K
authors: Zhu
authors: Juan
authors: J
authors: Hu
authors: Jinxing
authors: J
authors: Ye
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D007659:Ketones / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D007659:Ketones