title: Antinociceptive and antipyretic activities of amaranthus viridis linn in different experimental models.
abstract: Methanolic extract of whole plant of Amaranthus viridis L (MEAV), was screened for antinociceptive activity using acetic acid induced writhing test, hot plate test and tail immersion test in mice. In a similar way a screening exercise was carried out to determine the antipyretic potential of the extract using yeast induced pyrexia method in rats. Administration of the extracts was applied to both laboratory animals at the doses of 200 and 400 mg/kg body weight, respectively. The results of the statistical analysis showed that MEAV had significant (p<0.01) dose dependent antinociceptive and antipyretic properties at 200 and 400 mg/kg. Hence present investigation reveals the antinociceptive and antipyretic activities of methanolic extract of Amaranthus viridis.
authors: Department of Pharmacognosy, Sri K.V.College of Pharmacy, Chickballapur, Karnataka, India.
authors: Bagepalli Srinivas Ashok
authors: BS
authors: Kumar
authors: Kuruba
authors: K
authors: Lakshman
authors: Korala Konta Narsimha
authors: KK
authors: Jayaveera
authors: Devangam Sheshadri
authors: DS
authors: Shekar
authors: Chinna Swamy Vel
authors: CS
authors: Muragan
authors: Bachappa
authors: B
authors: Manoj
keywords: Analgesics; Animals; Dose response relationship; Methanol; Plant extracts