title: Gustatory receptor neuron responds to DEET and other insect repellents in the yellow-fever mosquito, Aedes aegypti.
abstract: Three gustatory receptor neurons were characterized for contact chemoreceptive sensilla on the labella of female yellow-fever mosquitoes, Aedes aegypti. The neuron with the smallest amplitude spike responded to the feeding deterrent, quinine, as well as N,N-diethyl-3-methylbenzamide and other insect repellents. Two other neurons with differing spikes responded to salt (NaCl) and sucrose. This is the first report of a gustatory receptor neuron specific for insect repellents in mosquitoes and may provide a tool for screening chemicals to discover novel or improved feeding deterrents and repellents for use in the management of arthropod disease vectors.
authors: Plant Sciences Institute, Henry A. Wallace Beltsville Agricultural Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA.
authors: Jillian L
authors: JL
authors: Sanford
authors: Vonnie D C
authors: VD
authors: Shields
authors: Joseph C
authors: JC
authors: Dickens
mesh_terms: D000330:Aedes / Q000187:drug effects* / Q000502:physiology; D000818:Animals; D002628:Chemoreceptor Cells / Q000187:drug effects; D055724:Electrophysiological Phenomena / Q000187:drug effects; D005260:Female; D007302:Insect Repellents / Q000494:pharmacology*; D012965:Sodium Chloride / Q000494:pharmacology; D013395:Sucrose / Q000494:pharmacology
chemical_list: D007302:Insect Repellents; D012965:Sodium Chloride; D013395:Sucrose