title: A one-pot 'green' synthesis of Pd-decorated PEDOT nanospheres for nonenzymatic hydrogen peroxide sensing.
abstract: We developed a novel nonenzymatic biosensor based on palladium/poly(3,4-ethylenedioxythiophene) (Pd/PEDOT) nanocomposite modified glassy carbon electrode (GCE) for the detection of hydrogen peroxide (H2O2). Pd/PEDOT has been successfully fabricated by a facile one-pot 'green' method using H2PdCl4 as an oxidant and a source of metal nanoparticles without any surfactants and templates. The as-synthesized PEDOT nanospheres are quite uniform in size (~60 nm) without aggregation and provide a good platform for anchoring the Pd nanoparticles (NPs). Pd NPs (~4.5 nm) are homogenously dispersed on surface of PEDOT nanospheres. The Pd/PEDOT nanospheres on GCE exhibit a good electrocatalytic activity towards the H2O2 reduction. The electrochemical response of Pd/PEDOT to H2O2 exhibits a low detection limit of 2.84 μM in the range of 2.5×10(-3)-1.0 mM with a high sensitivity, good repeatability, acceptable reproducibility and good long-term stability. The good recoveries achieved in spiked human urine samples demonstrated the potential application of Pd/PEDOT for H2O2 detection.
authors: College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, PR China.
authors: Fengxing
authors: F
authors: Jiang
authors: Ruirui
authors: R
authors: Yue
authors: Yukou
authors: Y
authors: Du
authors: Jingkun
authors: J
authors: Xu
authors: Ping
authors: P
authors: Yang
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D055664:Electrochemical Techniques / Q000295:instrumentation*; D004566:Electrodes; D055772:Green Chemistry Technology / Q000379:methods; D006801:Humans; D006861:Hydrogen Peroxide / Q000032:analysis / Q000652:urine*; D057230:Limit of Detection; D054118:Nanospheres / Q000737:chemistry* / Q000648:ultrastructure; D010165:Palladium / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D015203:Reproducibility of Results
chemical_list: D019086:Bridged Bicyclo Compounds, Heterocyclic; D011108:Polymers; C121383:poly(3,4-ethylene dioxythiophene); D010165:Palladium; D002244:Carbon; D006861:Hydrogen Peroxide