title: [Erdi Biejia decoction for erectile dysfunction with kidney-yin deficiency].
abstract: OBJECTIVE
  To observe the clinical efficacy of the Chinese medicine Erdi Biejia Decoction in the treatment of erectile dysfunction (ED) with kidney-yin deficiency, and explore its action mechanism and the nourishing yin doctrine in the treatment of ED.
  
  
  METHODS
  We equally randomized 60 ED patients with kidney-yin deficiency into a treatment and a control group, the former treated with oral Erdi Biejia Decoction, and the latter given placebo, for a course of 8 weeks. We compared the IIEF scores and levels of sex hormones T, E2, LH, FSH and PRL between the two groups before and after treatment.
  
  
  RESULTS
  Compared with the control group, the treatment group showed a significantly higher total effectiveness rate (36.67% vs 63.33%, P < 0.05), IIEF score (18.19 +/- 5.20 vs 23.08 +/-4.71, P < 0.05) and plasma T level (116.41 +/- 3.19 vs 20.14 +/- 2.99, P < 0.05), but remarkably lower levels of E2, LH, FSH and PRL (P < 0.05) after medication, all with statistically significant differences from pre-medication (P < 0.05).
  
  
  CONCLUSIONS
  Erdi Biejia Decoction is efficacious in the treatment of ED with kidney-yin deficiency, with no obvious adverse effects.
authors: Department of Andrology, Jiangsu Provincial Hospital of Traditional Chinese Medicine, Nanjing, Jiangsu 210029, China. njnjhj@yahoo.com.cn
authors: Jian
authors: J
authors: Huang
authors: Fu-Song
authors: FS
authors: Xu
mesh_terms: D000328:Adult; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D007172:Erectile Dysfunction / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D016896:Treatment Outcome; D016710:Yin Deficiency / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D004365:Drugs, Chinese Herbal; C527176:erdi biejia