title: Anti-demineralization effect of a novel fluoride-releasing varnish on dentin.
abstract: OBJECTIVE
  To investigate the laboratory anti-demineralization effect of a novel fluoride-releasing varnish containing surface reaction-type prereacted glass-ionomer (S-PRG) filler.
  
  
  METHODS
  Paired specimens were cut from bovine root dentin. One of each pair was used for the S-PRG group, and the other served as a control (n = 6). A 1 x 3 mm test surface was made on each specimen with the fluoride-releasing varnish. The novel fluoride-releasing varnish is categorized as a two-bottle-type self-etch adhesive. These liquids were mixed, applied on the test surface, and light-cured for 10 seconds. As a control, an S-PRG filler-free varnish was applied in the same manner. Each specimen was immersed in 8% methylcellulose gel demineralization system (1.5 mM Ca, 0.9 mM PO4, 0.1 M acetic acid, pH 5.0) for 7 days at 3 degrees C. The mineral profiles and integrated mineral loss (IML) of the lesions were obtained by transversal microradiography and analytical software.
  
  
  RESULTS
  The S-PRG group exhibited significantly thicker surface layer than the control group. Furthermore, the S-PRG group showed significantly lower IML (3,459 vol% xmicropm) than the control group (4,687 vol% xmicropm) ( P < 0.05, Welch's two-sample t-test). The novel fluoride-releasing varnish increased acid resistance of root dentin in the vicinity of the coated surface.
authors: Division of Restorative Dentistry, Department of Oral Medicine, Kanagawa Dental College, 82 Inaoka-cho, Yokosuka, Kanagawa 238-8580, Japan.
authors: Toru
authors: T
authors: Shiiya
authors: Yoshiharu
authors: Y
authors: Mukai
authors: Kiyoshi
authors: K
authors: Tomiyama
authors: Toshio
authors: T
authors: Teranaka
mesh_terms: D000818:Animals; D002417:Cattle; D003804:Dentin / Q000737:chemistry*; D005459:Fluorides / Q000737:chemistry*; D010150:Paint; D017001:Tooth Demineralization / Q000139:chemically induced*
chemical_list: D005459:Fluorides