title: Cerebral near-infrared spectroscopy during transition of healthy term newborns.
abstract: BACKGROUND
  Values of regional cerebral tissue oxygen saturation (cStO2) have been described during transition of term and preterm infants after birth. However, use of different devices precludes comparison of measurements.
  
  
  OBJECTIVE
  To measure cStO2 during transition of term infants using a calibrated 4-wavelength laser light source near-infrared spectroscopy oximeter (FORE-SIGHT) to obtain data that allow comparison with cStO2 of very-low-birth-weight (VLBW) infants using this oximeter and with cStO2 of term infants using different oximeters.
  
  
  METHODS
  cStO2 (FORE-SIGHT oximeter), preductal arterial oxygen saturation and heart rate were measured in 46 healthy term infants (n = 20 spontaneous delivery, n = 22 caesarean section, n = 4 assisted vaginal delivery) during the first 10 min after delivery.
  
  
  RESULTS
  The median (interquartile range) cStO2 at 2 min after birth was 42% (39-46) after spontaneous delivery, 42% (30-52) after caesarean section and 36% (20-53) after assisted vaginal delivery (no difference between groups). In association with increasing arterial oxygen saturation and heart rate, cStO2 increased continuously and reached a steady state approximately 8 min after birth of 62-77% (interquartile range) in all three groups.
  
  
  CONCLUSIONS
  Healthy term newborns had similar cStO2 changes from 2 min after birth regardless of the mode of delivery. cStO2 of healthy term infants was lower than cStO2 of VLBW infants during transition. cStO2 values as measured by the FORE-SIGHT oximeter seem in the range of values as measured by the NIRO 300 oximeter. They were lower than values as measured by the INVOS 5100 oximeter.
authors: Division of Neonatology and Pediatric Intensive Care, Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany.
authors: Munira
authors: M
authors: Almaazmi
authors: Manuel B
authors: MB
authors: Schmid
authors: Stefanie
authors: S
authors: Havers
authors: Frank
authors: F
authors: Reister
authors: Wolfgang
authors: W
authors: Lindner
authors: Benjamin
authors: B
authors: Mayer
authors: Helmut D
authors: HD
authors: Hummler
authors: Hans
authors: H
authors: Fuchs
mesh_terms: D000704:Analysis of Variance; D015415:Biomarkers / Q000097:blood; D002138:Calibration; D002560:Cerebrovascular Circulation; D002585:Cesarean Section; D004867:Equipment Design; D005260:Female; D005858:Germany; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D016014:Linear Models; D008297:Male; D009772:Obstetrical Forceps; D010092:Oximetry / Q000295:instrumentation / Q000592:standards; D010100:Oxygen / Q000097:blood*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012015:Reference Standards; D019265:Spectroscopy, Near-Infrared / Q000295:instrumentation / Q000592:standards; D047929:Term Birth / Q000097:blood*; D013997:Time Factors; D014620:Vacuum Extraction, Obstetrical
chemical_list: D015415:Biomarkers; D010100:Oxygen