title: [Raction of dopaminergic and vasopressinergic systems in sleep deprivation in rats].
abstract: Six hours sleep deprivation experiments were carried out on rats after threefold injection of D1 dopamine receptor antagonist SCH 39 166. Immunohistochemical study of striatum revealed the increase in D1 and D2 dopamine receptor and glutamate immunoreactive material during the sleep deprivation and 2 h of postdeprivation period. The level of AMPA glutamate receptors increased under the sleep deprivation and decreased in the postdeprivation period. The data obtained are discussed in association with dynamic of changes of vasopressin immunoreactivity in neurosecretory supraoptical and paraventricular nuclei of hypothalamus in these experiments and in experiments without D1 receptor antagonist pretreatment.
authors: G A
authors: GA
authors: Oganesian
authors: I V
authors: IV
authors: Romanova
authors: A L
authors: AL
authors: Mikhrina
authors: N M
authors: NM
authors: Paskarenko
authors: V V
authors: VV
authors: Kuzik
mesh_terms: D000818:Animals; D001552:Benzazepines / Q000494:pharmacology*; D018492:Dopamine Antagonists / Q000494:pharmacology*; D008297:Male; D010286:Paraventricular Hypothalamic Nucleus / Q000378:metabolism / Q000503:physiopathology; D051381:Rats; D017208:Rats, Wistar; D018091:Receptors, AMPA / Q000378:metabolism*; D017447:Receptors, Dopamine D1 / Q000378:metabolism; D017448:Receptors, Dopamine D2 / Q000378:metabolism; D012892:Sleep Deprivation / Q000378:metabolism* / Q000503:physiopathology; D013495:Supraoptic Nucleus / Q000378:metabolism / Q000503:physiopathology; D014667:Vasopressins / Q000378:metabolism*
chemical_list: D001552:Benzazepines; D018492:Dopamine Antagonists; D018091:Receptors, AMPA; D017447:Receptors, Dopamine D1; D017448:Receptors, Dopamine D2; C058081:ecopipam; D014667:Vasopressins