title: A new access to 4 H-quinolizines from 2-vinylpyridine and alkynes promoted by rhodium-N-heterocyclic-carbene catalysts.
abstract: Forging the lock that autolocks! Rh-NHC catalysts promote a new access to 4 H-quinolizine species from 2-vinylpyridine and terminal and internal alkynes through C-H activation and C-C coupling reactions (see figure). N-Bridgehead heterocycle formation is favored for internal- over terminal-substituted butadienylpyridine derivatives in a thermal 6π-electrocyclization process.
authors: Departamento Química Inorgánica, Instituto Síntesis Química y Catálisis Homogénea, Universidad de Zaragoza-CSIC, Pl. S. Francisco S/N 50009 Zaragoza, Spain.
authors: Ramón
authors: R
authors: Azpíroz
authors: Andrea
authors: A
authors: Di Giuseppe
authors: Ricardo
authors: R
authors: Castarlenas
authors: Jesús J
authors: JJ
authors: Pérez-Torrente
authors: Luis A
authors: LA
authors: Oro
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives / Q000737:chemistry; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry*; D011807:Quinolizines / Q000138:chemical synthesis* / Q000737:chemistry*; D012238:Rhodium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D056831:Coordination Complexes; D011725:Pyridines; D011807:Quinolizines; C030011:carbene; D012238:Rhodium; C030953:2-vinylpyridine; D008697:Methane