title: Polymorphisms in FGFBP1 and FGFBP2 genes associated with carcass and meat quality traits in chickens.
abstract: In the  past, the focus of broiler breeding programs on yield and carcass traits improvement  led to problems related to meat quality. Awareness of public concern for  quality resulted in inclusion of meat quality traits in the evaluation process.  Nevertheless, few genes associated with meat quality attributes are known.  Previous studies mapped quantitative trait loci for weight at 35 and 42 days in  a region of GGA4 flanked by the microsatellite markers, MCW0240 and LEI0063. In this region, there are 2 fibroblast growth factor binding  protein (FGFBP) genes that play an important role in embryogenesis,  cellular differentiation, and proliferation in chickens. The objective of this  study was to identify and associate single nucleotide polymorphisms (SNPs) in FGFBP1 and FGFBP2 with performance, carcass, and meat quality in  experimental and commercial chicken populations. In the commercial population,  SNP g.2014G>A in FGFBP1 was associated with decreased carcass weight  (P < 0.05), and SNP g.651G>A in FGFBP2 was associated with thawing  loss and meat redness content (P < 0.05). Four haplotypes were constructed  based on 2 SNPs and were associated with breast weight, thawing loss, and meat  redness content. The diplotypes were associated with thawing loss, lightness,  and redness content. The SNPs evaluated in the present study may be used as  markers in poultry breeding programs to aid in improving growth and meat  quality traits.
authors: Departamento de Zootecnia, Escola Superior de Agricultura Luiz de Queiroz, Universidade de São Paulo, Piracicaba, SP, Brasil.
authors: A M
authors: AM
authors: Felício
authors: C
authors: C
authors: Boschiero
authors: J C C
authors: JC
authors: Balieiro
authors: M C
authors: MC
authors: Ledur
authors: J B S
authors: JB
authors: Ferraz
authors: A S A M T
authors: AS
authors: Moura
authors: L L
authors: LL
authors: Coutinho
mesh_terms: D000818:Animals; D001835:Body Weight / Q000235:genetics; D002645:Chickens / Q000235:genetics*; D063427:Food Quality; D005787:Gene Frequency; D006239:Haplotypes / Q000235:genetics; D036341:Intercellular Signaling Peptides and Proteins / Q000235:genetics*; D008460:Meat / Q000592:standards*; D018895:Microsatellite Repeats; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide; D040641:Quantitative Trait Loci
chemical_list: D036341:Intercellular Signaling Peptides and Proteins