title: Isothermal amplification system based on template-dependent extension.
abstract: A novel template-dependent extension based isothermal amplification (TEIA) system with high single-base discrimination capability is developed, where the interference caused by non-specific reaction in isothermal strand displacement amplification (SDA) technique is substantially avoided via using a functionalized template probe, showing potential value in the development and application of SDA based detection devices.
authors: State Key Laboratory for Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, PR China.
authors: Hui
authors: H
authors: Zhou
authors: Su-Jin
authors: SJ
authors: Xie
authors: Song-Bai
authors: SB
authors: Zhang
authors: Guo-Li
authors: GL
authors: Shen
authors: Ru-Qin
authors: RQ
authors: Yu
authors: Zai-Sheng
authors: ZS
authors: Wu
mesh_terms: D020137:Base Pair Mismatch; D004247:DNA / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D021141:Nucleic Acid Amplification Techniques; D015345:Oligonucleotide Probes / Q000737:chemistry / Q000378:metabolism; D020641:Polymorphism, Single Nucleotide; D013050:Spectrometry, Fluorescence
chemical_list: D015345:Oligonucleotide Probes; D004247:DNA