title: The role of gastroesophageal reflux disease questionnaire in the Republic of Macedonia.
abstract: OBJECTIVE
  Gastroesophageal reflux disease is a common disease with a multifactorial pathogenesis. Our aim was to analyse the role of the Gastroesophageal Disease Questionnaire in diagnosing reflux disease in the population of the Republic of Macedonia.
  
  
  METHODS
  The questionnaire on the severity of the symptoms related to GERD was used. An evaluation of the distal portion of the oesophagus was carried out in all patients with positive questionnaire results. All mucosal injury was classified by the Los Angeles criteria (LA).
  
  
  RESULTS
  642 patients were included. 58.73% females, with an average age of 37.5±8.2. Females had a higher BMI than males 26.8±4.1 vs. 24.9±3.8 p<0.001. Of the total number of examinees (642 patients), in those with erosive reflux disease and also in those with nonerosive reflux disease, as shown respectively in endoscopy, the sensitivity of the RDQ was 100%, and the specifity was 0%. The100 sensitivity means that the questionnaire verified/diagnosed patients with erosive reflux disease with 100% certainty.
  
  
  CONCLUSIONS
  RESULTS were found in some studies comparing the positive Reflux Disease Questionnaire and the level of erosive esophagitis (LA classification). This study provides evidence that the RDQ represents a viable instrument for assessing symptom severity and response to treatment in clinical trials of patients with GERD, but in patients with a high score, endoscopic evaluation should not be excluded.
authors: Gastroenterohepatology Clinic, Clinical Centre, Ss Cyril and Methodius University, Skopje, R. Macedonia.
authors: K
authors: K
authors: Grivcheva Stardelova
authors: R
authors: R
authors: Popova
authors: N
authors: N
authors: Joksimovic
authors: Gj
authors: G
authors: Deriban
authors: M
authors: M
authors: Zdravkovska
authors: V
authors: V
authors: Serafimoski
mesh_terms: D000328:Adult; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005764:Gastroesophageal Reflux / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D008297:Male; D011446:Prospective Studies; D018843:Republic of North Macedonia / Q000453:epidemiology; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires