title: NIS-mediated electrophilic cyclization of 3-silyloxy-1,n-enynes.
abstract: The electrophilic cyclization of 3-silyloxy-1,5-enynes and 3-silyloxy-1,6-enynes was investigated. In the presence of N-iodosuccinimide (NIS), the title compounds are transformed under metal-free conditions into five-membered carbocycles with all-carbon stereogenic centers following a sequence of iodonium activation of the triple bond, carbocyclization, and pinacol-type 1,2-shift.
authors: Organic Chemistry, Bergische Universität Wuppertal, Gaußstr. 20, 42119 Wuppertal, Germany.
authors: Florian
authors: F
authors: Huber
authors: Stefan F
authors: SF
authors: Kirsch