title: Ester hydrolysis by a histidine-containing cavitein.
abstract: We have used a template-assembled synthetic protein (TASP) to investigate catalytic function in ester hydrolysis. A histidine-containing cavitein has been found to catalyze ester hydrolysis with a rate increase of 18 times that of background.
authors: Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC, Canada V6T 1Z1.
authors: Hui
authors: H
authors: Yang
authors: John C
authors: JC
authors: Sherman
mesh_terms: D055162:Biocatalysis; D002384:Catalysis; D004952:Esters; D004988:Ethers, Cyclic / Q000737:chemistry*; D006639:Histidine / Q000737:chemistry*; D006868:Hydrolysis; D011506:Proteins / Q000737:chemistry / Q000378:metabolism; D012118:Resorcinols / Q000737:chemistry*
chemical_list: D004952:Esters; D004988:Ethers, Cyclic; D011506:Proteins; D012118:Resorcinols; C442939:cavitand; D006639:Histidine