title: Monophasic catalytic system for the selective semireduction of alkynes.
abstract: A highly efficient semireduction of alkynes has been developed. Using 0.5-2 mol % of a copper catalyst, semireduction can be accomplished with a wide range of substrates, including both internal and terminal alkynes without over-reduction. The new method has excellent chemoselectivity, and the semireduction can be accomplished even in the presence of nitro and aryl iodo groups. Finally, commercial availability of a catalyst precursor adds to the appeal of the new catalytic system.
authors: Department of Chemistry, University of Washington, Seattle, Washington 98195, USA.
authors: Aaron M
authors: AM
authors: Whittaker
authors: Gojko
authors: G
authors: Lalic