title: Hepatic enzymes activity in the fish Prochilodus lineatus (Valenciennes, 1836) after sublethal cypermethrin exposure.
abstract: Prochilodus lineatus, a fish, was exposed to sublethal concentrations of cypermethrin: 0.075, 0.150, and 0.300 μg L(-1) and a control group (without cypermethrin) for 96 h. Five specimens were exposed in each concentration for triplicate (n = 60). Hepatic biochemical values and behavioral changes were studied. The results revealed a significantly higher level of aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase in hepatic tissue at different concentrations of cypermethrin tested compared to control (p < 0.05). A decrease in total protein was observed in exposed groups but not significantly (p > 0.05). This study provides information to know toxic mechanisms of cypermethrin on hepatic enzymes of P. lineatus that are poorly understood.
authors: Cátedra de Toxicología y Bioquímica Legal, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, Ciudad Universitaria, Paraje El Pozo C.C 242 (3000), Santa Fe, Argentina.
authors: A
authors: A
authors: Loteste
authors: J
authors: J
authors: Scagnetti
authors: M F
authors: MF
authors: Simoniello
authors: M
authors: M
authors: Campana
authors: M J
authors: MJ
authors: Parma
mesh_terms: D000410:Alanine Transaminase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D001219:Aspartate Aminotransferases / Q000378:metabolism; D060125:Characiformes; D007306:Insecticides / Q000633:toxicity*; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D011722:Pyrethrins / Q000633:toxicity*; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D007306:Insecticides; D011722:Pyrethrins; D014874:Water Pollutants, Chemical; C017160:cypermethrin; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase