title: Botulinum toxin type A in chronic plantar fasciitis: clinical effects one year after injection.
abstract: OBJECTIVE
  To determine whether the efficacy of botulinum toxin type A in chronic plantar fasciitis was maintained for more than six months after treatment.
  
  
  METHODS
  Observational follow-up study.
  
  
  METHODS
  Twenty-four patients who received botulinum toxin type A injection in a previous randomized study of chronic plantar fasciitis (active treatment group) and who presented a benefit one month after treatment.
  
  
  METHODS
  A visual analogue scale for pain and the Foot Health Status Questionnaire were used to re-evaluate results 12 months after the botulinum toxin injection. No further injections of botulinum toxin had been administered during the follow-up period. Patients were also asked to give a subjective assessment of treatment outcome.
  
  
  RESULTS
  At 12 months, compared with the six-month evaluation, there was a further improvement in foot pain measured using the visual analogue scale, though this did not reach significance (1.78 at 6 months versus 1.22 at 12 months; P = 0.142). However, there were significant improvements in two domains of Foot Health Status Questionnaire: foot pain (91.11 at 6 months versus 80.00 at 12 months; P = 0.001) and foot function (96.19 at 6 months versus 89.38 at 12 months; P = 0.047). There was a small, non-significant deterioration in the shoe and foot health domains. Satisfaction with the outcome was good or very good in the large majority of patients.
  
  
  CONCLUSIONS
  In patients with chronic plantar fasciitis, the positive effect detected six months after treatment with botulinum toxin type A was maintained at 12 months and there was a further improvement in pain and foot function.
authors: Department of Physical Medicine and Rehabilitation, Alicante University General Hospital, Alicante, Spain. diaz_ism@gva.es
authors: Ismael V
authors: IV
authors: Díaz-Llopis
authors: Diego
authors: D
authors: Gómez-Gallego
authors: Francisco J
authors: FJ
authors: Mondéjar-Gómez
authors: Alfredo
authors: A
authors: López-García
authors: Jose M
authors: JM
authors: Climent-Barberá
authors: Carmen M
authors: CM
authors: Rodríguez-Ruiz
mesh_terms: D019274:Botulinum Toxins, Type A / Q000008:administration & dosage / Q000627:therapeutic use*; D002908:Chronic Disease; D036981:Fasciitis, Plantar / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D009465:Neuromuscular Agents / Q000008:administration & dosage / Q000627:therapeutic use; D010146:Pain / Q000188:drug therapy*; D010147:Pain Measurement; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A
keywords: Plantar fasciitis; botulinum toxin; treatment