title: Effect of longitudinal changes in visceral fat area on incidence of metabolic risk factors: the Hitachi health study.
abstract: OBJECTIVE
  To examine the incidences of metabolic risk factors according to changes in visceral fat area (VFA) in a large Japanese population.
  
  
  METHODS
  The subjects were 973 men who received a computed tomography (CT) examination in health checkups twice (2004-2005 and 2007-2008), and not having two or more of metabolic risk factors (except for the waist circumference) in 2004-2005. VFA was measured using CT. To assess the potential influence of changes in VFA for the 3-year incidences of each metabolic risk factor and clustering metabolic risk factors, logistic regression analyses were used.
  
  
  RESULTS
  A significant association was observed between the change in VFA and the components of the metabolic risk factors. Incidences of the components of the metabolic risk factors were significantly higher among subjects with a larger increase in VFA and were significantly lower among subjects with a larger decrease in VFA (trend P < 0.001). Significant increases in the odds ratios for the incidences of high triglycerides and low high-density lipoprotein cholesterol level were observed among subjects with ≥50 cm(2) VFA increase.
  
  
  CONCLUSIONS
  The adoption of a lifestyle that does not increase the VFA is important for preventing metabolic syndrome.
authors: Department of Clinical Research, National Center for Global Health and Medicine, Tokyo, Japan.
authors: Yumi
authors: Y
authors: Matsushita
authors: Toru
authors: T
authors: Nakagawa
authors: Shuichiro
authors: S
authors: Yamamoto
authors: Yoshihiko
authors: Y
authors: Takahashi
authors: Tetsuji
authors: T
authors: Yokoyama
authors: Tetsuya
authors: T
authors: Mizoue
authors: Mitsuhiko
authors: M
authors: Noda
mesh_terms: D000328:Adult; D000368:Aged; D044466:Asian People; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D050152:Intra-Abdominal Fat; D008019:Life Style; D016015:Logistic Models; D008137:Longitudinal Studies; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis* / Q000453:epidemiology*; D008875:Middle Aged; D012307:Risk Factors; D014057:Tomography, X-Ray Computed; D055105:Waist Circumference