title: [Optimised rate of specific, revascularising therapies in acute stroke--what is the aim? Considerations from the experience of a tertiary centre].
abstract: BACKGROUND
  Recanalisation favourably influences outcome in acute stroke. Improved endovascular approaches seem to have higher recanalisation rates than systemic thrombolysis. Substantial efforts have been undertaken to increase the proportion of patients to whom these therapies can be applied. It is still unclear what rates can be realised in a clinical setting.
  
  
  METHODS
  This is a retrospective single-centre analysis of patients with acute ischaemic stroke and specific recanalisation therapy primarily admitted to our tertiary care centre from 1/2010 to 3/2012.
  
  
  RESULTS
  20 % of patients received systemic thrombolysis, 20 % of these additional endovascular strategies. Pathological multimodal CT patterns were more common in patients not fulfilling the inclusion criteria for thrombolysis. Short-term clinical outcomes were similar in on-label and off-label applications.
  
  
  CONCLUSIONS
  Structured clinical pathways including multimodal CT imaging are useful in identifying patients likely to profit from revascularisation therapies. Based upon our data, some realistic aims concerning therapy rates in patients with ischaemic stroke treated in everyday practice may be formulated (20/20 in 2020).
authors: Neurologie, Universitätsklinikum Knappschaftskrankenhaus Bochum, Germany. eyding@web.de
authors: J
authors: J
authors: Eyding
authors: W
authors: W
authors: Grönheit
authors: S
authors: S
authors: Rother
authors: S
authors: S
authors: Skodda
authors: L
authors: L
authors: Heuser
authors: A
authors: A
authors: Alekseyev
authors: U
authors: U
authors: Schlegel
mesh_terms: D000369:Aged, 80 and over; D002548:Cerebral Revascularization / Q000379:methods*; D057510:Endovascular Procedures; D005260:Female; D006801:Humans; D038801:International Classification of Diseases; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D020521:Stroke / Q000188:drug therapy / Q000601:surgery*; D015912:Thrombolytic Therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome