title: Comparison of central corneal thickness measured with anterior segment optical coherence tomography versus ultrasonic pachymetry.
abstract: OBJECTIVE
  To compare central corneal thickness measured with anterior segment optical coherence tomography (AS-OCT) and ultrasonic pachymetry (UP).
  
  
  METHODS
  A prospective, observational and cross-sectional study was performed. The central corneal thickness was measured in 112 eyes of 112 consecutive patients with AS-OCT and UP. All examinations were performed by the same examiner. The measurements obtained between the 2 instruments were compared to assess the level of agreement.
  
  
  RESULTS
  The average corneal thickness value obtained by AS-OCT was 531.47 ± 26.23 μm, while that measured by UP was 532.51 ± 26.04 μm. The intraclass correlation coefficient was 0.957 (P <.001). The Student's t-test did not show a statistically significant difference (1.04 ± 7.70 μm, P =.158). Finally, the Bland-Altman analysis showed a high level of agreement between 2 methods of measurement.
  
  
  CONCLUSIONS
  In the context of normal corneas, there was good agreement between the measurement of central corneal thickness with AS-OCT and UP, although there was a slight overestimation of the measurement using UP (1.04 μm).
authors: Servicio de Oftalmología, Hospital Provincial de la Misericordia, Toledo, Spain. carloslazarogarcia@gmail.com
authors: C
authors: C
authors: Lázaro
authors: E M
authors: EM
authors: Hernández
authors: D
authors: D
authors: Martínez
authors: P
authors: P
authors: Redondo
mesh_terms: D003315:Cornea / Q000000981:diagnostic imaging* / Q000473:pathology*; D063171:Corneal Pachymetry / Q000379:methods*; D003430:Cross-Sectional Studies; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods; D014463:Ultrasonography