title: [Mild asthma in children: new data and a revival of interest].
abstract: According to the Global Initiative for Asthma (GINA) classification, mild asthma includes intermittent and mild persistent asthma. It represents more than 75% of asthmatic children. The symptoms and functional impact are well described. Mild asthma can lead to severe exacerbations. Progression to more severe disease may occur. Consequently, it is important to diagnose mild asthma, to initiate the appropriate treatment early, and to identify the risk factors for aggravation. Nevertheless, mild asthma is under-diagnosed and under-treated. Bronchial inflammation and remodeling are observed in mild asthma. A daily low-dose of inhaled corticosteroids is the reference treatment for mild persistent asthma. Intermittent inhaled corticosteroids cannot be recommended in children with mild persistent asthma.
authors: Unité de pneumologie et allergologie pédiatriques, pôle de pédiatrie, hôpital Jeanne-de-Flandre, CHRU de Lille, avenue Eugène-Avinée, 59037 Lille cedex, France. antoine.deschildre@chru-lille.fr
authors: A
authors: A
authors: Deschildre
authors: I
authors: I
authors: Tillie Leblond
authors: C
authors: C
authors: Mordacq
authors: J
authors: J
authors: de Blic
authors: P
authors: P
authors: Scheinmann
authors: P
authors: P
authors: Chanez
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use; D000328:Adult; D017668:Age of Onset; D056151:Airway Remodeling; D018927:Anti-Asthmatic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000503:physiopathology; D001991:Bronchitis / Q000150:complications / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D015897:Comorbidity; D000075202:Contraindications; D018450:Disease Progression; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007223:Infant; D020024:Leukotriene Antagonists / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology; D010641:Phenotype; D012307:Risk Factors; D017678:Sex Distribution; D063189:Symptom Assessment
chemical_list: D000305:Adrenal Cortex Hormones; D018927:Anti-Asthmatic Agents; D020024:Leukotriene Antagonists