title: Two new compounds from the metabolites of a marine-derived actinomycete Streptomyces cavourensis YY01-17.
abstract: Our current marine natural product program investigated the second metabolites of an actinomycete Streptomyces cavourensis YY01-17 originating from the Antarctic ecological niche to discover potential antitumor chemical entities. Two new compounds, along with a known compound, were isolated from the ethyl acetate extract of the fermentation broth of the marine-derived actinomycete, and their structures were elucidated, respectively, as 2(S)-3'-hydroxybutan-2'-yl 2-hydroxypropanoate (1), (E)-3-hydroxy-2,4-dimethylhept-4-enamide (2), and 2-hydroxy-3-methylbutanoic acid (3) on the basis of spectroscopic data interpretation.
authors: School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.
authors: Shan-Shan
authors: SS
authors: Su
authors: Li
authors: L
authors: Tian
authors: Gang
authors: G
authors: Chen
authors: Zhan-Qiang
authors: ZQ
authors: Li
authors: Wen-Feng
authors: WF
authors: Xu
authors: Yue-Hu
authors: YH
authors: Pei
mesh_terms: D000577:Amides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000864:Antarctic Regions; D004354:Drug Screening Assays, Antitumor; D005285:Fermentation; D008011:Lichens / Q000382:microbiology; D008386:Marine Biology; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011422:Propionates / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013302:Streptomyces / Q000737:chemistry*
chemical_list: C582456:(E)-3-hydroxy-2,4-dimethylhept-4-enamide; C582455:2(S)-3'-hydroxybutan-2'-yl 2-hydroxypropanoate; D000577:Amides; D011422:Propionates