title: [Indexes of integrative activity of motor system in norm and at neuromotor pathology].
abstract: Characteristics of integrative activity of motor control system are received by the methods of the time series analysis. The methods allow to give an objective estimation of human brain pyramidal and extrapyramidal systems functional state. Authors consider the voluntary regulation of isometric effort as a model of movement and investigate this effort as the integrative motor output of a motor control system. Using of peculiar methodology of non-invasive research of parameters of isometric effort as indexes of CNS integrative activity, and application of modern methods of the time-series analysis has allowed to receive a new data concerning an estimation of activity of structures of motor control system in norm and in some neurodegenerative diseases of CNS (Parkinson's diseases, multiple sclerosis). These results represent the new knowledge in the field of movement physiology, and also expand opportunity of hardware diagnostics of neuromotor dysfunctions.
authors: Z A
authors: ZA
authors: Aleksanian
authors: S P
authors: SP
authors: Romanov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001921:Brain / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007537:Isometric Contraction; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000503:physiopathology*; D010300:Parkinson Disease / Q000175:diagnosis / Q000503:physiopathology*