title: Does binge drinking during early pregnancy increase the risk of psychomotor deficits?
abstract: BACKGROUND
  The potential effects of binge drinking during pregnancy on child motor function have only been assessed in a few, small studies. We aimed to examine the effects of binge alcohol consumption during early pregnancy, including number of binge episodes and timing of binge drinking, on child motor function at age 5.
  
  
  METHODS
  We performed a prospective follow-up study of 678 women and their children sampled from the Danish National Birth Cohort based on maternal alcohol consumption during pregnancy. At 5 years of age, the children were tested with the Movement Assessment Battery for Children. Parental education, maternal IQ, prenatal maternal smoking, the child's age at testing, sex of child, and tester were considered core confounders, while the full model also controlled for prenatal maternal average alcohol intake, maternal age and prepregnancy body mass index, parity, home environment, postnatal parental smoking, health status, participation in organized sport, and indicators for hearing and vision impairment.
  
  
  RESULTS
  There were no systematic or significant differences in motor function between children of mothers reporting isolated episodes of binge drinking and children of mothers with no binge episodes. No association was observed with respect to the number of binge episodes (maximum of 12) and timing of binge drinking.
  
  
  CONCLUSIONS
  In this study, we found no systematic association between isolated episodes of binge drinking during early pregnancy and child motor function at age 5.
authors: Department of Obstetrics and Gynaecology (USK), Aarhus University Hospital, Aarhus, Denmark. ukes@soci.au.dk
authors: Ulrik Schiøler
authors: US
authors: Kesmodel
authors: Bjørn
authors: B
authors: Bay
authors: Theresa
authors: T
authors: Wimberley
authors: Hanne-Lise F
authors: HL
authors: Eriksen
authors: Erik Lykke
authors: EL
authors: Mortensen
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000009:adverse effects / Q000453:epidemiology / Q000503:physiopathology; D063425:Binge Drinking / Q000453:epidemiology* / Q000503:physiopathology; D002675:Child, Preschool; D003718:Denmark / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011247:Pregnancy; D011261:Pregnancy Trimester, First / Q000187:drug effects* / Q000502:physiology; D011297:Prenatal Exposure Delayed Effects / Q000453:epidemiology* / Q000503:physiopathology; D011446:Prospective Studies; D011596:Psychomotor Disorders / Q000453:epidemiology* / Q000503:physiopathology; D012307:Risk Factors
keywords: Binge Drinking; Low-Moderate Alcohol Consumption; Motor Function; Prenatal Exposures