title: ERCP with intracholedocal biopsy for the diagnosis of biliary tract rhabdomyosarcoma in children.
abstract: Rhabdomyosarcoma is the most common tumor of the biliary tract in children. Although some features at preoperative radiographic studies (ultrasound, CT, MRI) may be suggestive of BT-RMS, until few years ago the final diagnosis was obtained by either operative or transcutaneous biopsy, thus exposing to a risk of regional dissemination. More recent and still anecdotal, is the histological diagnosis on tissue obtained by transluminal biopsy either during transhepatic cholangiography or endoscopic retrograde cholangio-pancreatography (ERCP), the latter having the major advantage of a much lower risk of loco-regional dissemination. We present two cases of BT-RMS that were histologically diagnosed by intracholedocal biopsy performed during ERCP, after being suspected at conventional imaging.
authors: Hepatobiliopancreatic Surgery Unit, Department of Pediatric Surgery and Transplantation, Bambino Gesù Children's Hospital, IRCCS, Piazza San Onofrio 4, 00165 Rome, Italy. fscottoni@msn.com
authors: F
authors: F
authors: Scottoni
authors: P
authors: P
authors: De Angelis
authors: L
authors: L
authors: Dall'Oglio
authors: P
authors: P
authors: Francalanci
authors: L
authors: L
authors: Monti
authors: J
authors: J
authors: de Ville de Goyet
mesh_terms: D001706:Biopsy / Q000379:methods*; D002675:Child, Preschool; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods*; D003135:Common Bile Duct / Q000473:pathology*; D003138:Common Bile Duct Neoplasms / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D015203:Reproducibility of Results; D012208:Rhabdomyosarcoma / Q000175:diagnosis*