title: [The study of antimicrobial properties of silver nanoparticles in the form of a colloidal solution in the matrix of finely dispersed silica].
abstract: In the experimental study obtained with chemical method colloid solution of nanoparticles (NPs) of silver (Ag) and a composite on his base in the matrix of finely dispersed silica with particle size of 8-12 nm and NPs concentration in basic solution of 0,0016% (0,016 mg/cm3) were established to exhibit high antimicrobial activity against the test organisms: E. coli, P. aeruginosa, S. Aureus and C. Albicans, which depended on a set of factors. Antibacterial properties of tissue impregnated with Ag-NPs were studied. As stabilizing substances a mixture of surface-active substance sodium dodecyl sulfate and polymer polyvinylpyrrolidone was used Before the beginning of the study effective neutralizer was tailored. Times of preservation of antimicrobial activity of test samples have been established, and also their stability throughout long term of supervision (24 months) has been shown. Effect of organic pollution on antimicrobal activity of the samples has been studied. Based on obtained results the algorithm of the study of antimicrobial properties of nanopreparations has been elaborated.
authors: G I
authors: GI
authors: Korchak
authors: E V
authors: EV
authors: Surmasheva
authors: A I
authors: AI
authors: Mikhienkova
authors: N A
authors: NA
authors: Nikonova
authors: L I
authors: LI
authors: Romanenko
authors: Z A
authors: ZA
authors: Oliĭnyk
authors: A K
authors: AK
authors: Gorval'
authors: M A
authors: MA
authors: Rosada
mesh_terms: D000465:Algorithms; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D003102:Colloids; D004305:Dose-Response Relationship, Drug; D004339:Drug Compounding; D053768:Metal Nanoparticles; D008826:Microbial Sensitivity Tests; D012822:Silicon Dioxide / Q000737:chemistry*; D012834:Silver / Q000737:chemistry / Q000494:pharmacology*; D012996:Solutions; D013499:Surface Properties
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D003102:Colloids; D012996:Solutions; D012834:Silver; D012822:Silicon Dioxide