title: Anti-Müllerian hormone and polycystic ovary syndrome: assessment of the clinical pregnancy rates in in vitro fertilization patients.
abstract: OBJECTIVE
  The purpose of this study is to investigate the role of serum anti-Müllerian hormone (AMH), follicle-stimulating hormone (FSH) and antral follicle count (AFC) for the prediction of clinical pregnancy rates (CPR) in women with polycystic ovary syndrome (PCOS) undergoing IVF treatment.
  
  
  METHODS
  Prospective cohort study.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  One hundred and fifty consecutive women with PCOS.
  
  
  METHODS
  All women underwent controlled ovarian stimulation with long agonist protocol followed by IVF procedure. Outcomes of pregnant and non-pregnant groups were compared.
  
  
  METHODS
  CPR; AMH, FSH and AFC means and percentiles.
  
  
  RESULTS
  Fifty-one (34%) clinical pregnancies were observed in 150 women. Mean AMH was 6.7 ± 2.8 and 7.1 ± 4.3 ng/mL in pregnant and non-pregnant women, respectively (p = 0.594). The CPR were 27.8%, 35.0% and 37.8% in <25%, 25%-75% and >75% AMH percentiles, respectively (p = 0.656). There were also no significant difference in mean FSH and AFC between pregnant and non-pregnant women (p = 0.484 and p = 0.165, respectively).
  
  
  CONCLUSIONS
  AMH, FSH and AFC are not predictive for CPR in women with PCOS undergoing IVF treatment. Mean AMH values were not significantly different between pregnant and non-pregnant women. Although CRP increased in parallel with the raise in AMH percentiles, this remained insignificant.
authors: Cerrahpasa School of Medicine, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and IVF unit, Istanbul University, Istanbul, Turkey. sahmay@yahoo.com
authors: Sezai
authors: S
authors: Sahmay
authors: Onur
authors: O
authors: Guralp
authors: Begum
authors: B
authors: Aydogan
authors: Ismail
authors: I
authors: Cepni
authors: Engin
authors: E
authors: Oral
authors: Tulay
authors: T
authors: Irez
mesh_terms: D000328:Adult; D054304:Anti-Mullerian Hormone / Q000097:blood*; D005260:Female; D005307:Fertilization in Vitro; D005640:Follicle Stimulating Hormone / Q000097:blood*; D006801:Humans; D006080:Ovarian Follicle / Q000166:cytology*; D011085:Polycystic Ovary Syndrome / Q000097:blood*; D011237:Predictive Value of Tests; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies; D055815:Young Adult
chemical_list: D054304:Anti-Mullerian Hormone; D005640:Follicle Stimulating Hormone