title: Five years' experience using oocyte vitrification to preserve fertility for medical and nonmedical indications.
abstract: OBJECTIVE
  To evaluate the results of controlled ovarian hyperstimulation (COH) for oocyte vitrification to preserve fertility for medical and nonmedical indications.
  
  
  METHODS
  A retrospective, multicenter, observational study performed between March 2007 and June 2012.
  
  
  METHODS
  University-affiliated infertility clinics.
  
  
  METHODS
  Of 560 nononcological patients and 475 oncological patients, we performed 1,080 oocyte vitrification cycles, 725 for nonmedical reasons and 355 in patients affected with cancer. Cycle outcome is presented, including 30 women who returned to use their frozen eggs with, 20 pregnancies obtained, 6 newborns, and 8 ongoing pregnancies.
  
  
  METHODS
  Controlled ovarian hyperstimulation, oocyte retrieval, warming of oocytes, and ET in those who already came back.
  
  
  METHODS
  Days of stimulation, total dose of gonadotropins, estrogen (E) and P levels, number of oocytes retrieved and vitrified, pregnancy rate (PR).
  
  
  RESULTS
  Comparable results were obtained in both groups of patients, with lower total dose of gonadotropins used and lower serum E(2) levels in patients affected with cancer. Frozen/thawed oocytes performed similarly in both groups.
  
  
  CONCLUSIONS
  Patients who vitrify eggs for medical or nonmedical reasons perform similarly, as observed in this large series. This technique offers realistic expectations to both groups of patients to have a child with their own eggs. These data could be used to adequately counsel our patients.
authors: IVI-Madrid, Madrid, Spain. juan.garcia.velasco@ivi.es
authors: Juan A
authors: JA
authors: Garcia-Velasco
authors: Javier
authors: J
authors: Domingo
authors: Ana
authors: A
authors: Cobo
authors: Maria
authors: M
authors: Martínez
authors: Luis
authors: L
authors: Carmona
authors: Antonio
authors: A
authors: Pellicer
mesh_terms: D000328:Adult; D016009:Chi-Square Distribution; D015925:Cryopreservation; D004624:Embryo Transfer; D005260:Female; D059247:Fertility Preservation / Q000379:methods*; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D050498:Live Birth; D054315:Oocyte Retrieval; D010062:Ovulation Induction; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies; D013030:Spain; D013997:Time Factors; D016896:Treatment Outcome; D058989:Vitrification