title: Mycophenolate mofetil-induced colitis with graft versus host disease-like features in a liver transplant recipient.
abstract: Mycophenolate mofetil (MMF) is a commonly used immunosuppressive drug in the management of transplant recipients. Gastrointestinal (GI) toxicity (diarrhea) is the most frequently reported adverse event in MMF-treated transplant patients. MMF-induced Graft versus Host Disease has rarely been reported in literature. We report a case of MMF-induced colitis with Graft versus Host Disease-like features, to highlight the importance of high clinical suspicion for its diagnosis, and that appropriate management in such a setting can reduce morbidity and mortality. We also review the relevant literature.
authors: Department of Pathology, Global Hospitals and Health City, Chennai, Tamilnadu, India.
authors: Sushma
authors: S
authors: Patra
authors: Mukul
authors: M
authors: Vij
authors: B
authors: B
authors: Sukanya
authors: Dharmesh
authors: D
authors: Kapoor
mesh_terms: D003092:Colitis / Q000139:chemically induced* / Q000473:pathology*; D006086:Graft vs Host Disease / Q000473:pathology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D009173:Mycophenolic Acid / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D014180:Transplantation
chemical_list: D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid