title: High-sensitivity C-reactive protein (hs-CRP) and tumor necrotizing factor-alpha (TNF-alpha) after on- and off- pump coronary artery bypass grafting.
abstract: BACKGROUND
  Coronary artery bypass grafting (CABG) is one of the most frequently performed operations around the world. The aim of this study is to evaluate high-sensitivity C-reactive protein (hs-CRP) and tumor necrosis factor-alpha (TNF-alpha) differences between on-pump and off-pump coronary surgery.
  
  
  METHODS
  In this prospective study, 90 patients with coronary artery disease referred for CABG were enrolled from July 2006-November 2007. Levels of hs-CRP and TNF-alpha were measured by ELISA using commercial kits
  
  
  RESULTS
  hs-CRP levels significantly (p<0.001) increase after CABG. But no difference between off-pump and on-pump groups was noted for hs-CRP and TNF-alpha levels (p=0.4, p=0.8).
  
  
  CONCLUSIONS
  There was no difference in high-sensitivity C-reactive protein (hs-CRP) and TNF-alpha between on-pump and off-pump CABG surgery.
authors: Department of Cardiology, Tabriz University (Medical Sciences), Tabriz, Iran.
authors: H
authors: H
authors: Javadzadegan
authors: N
authors: N
authors: Nezami
authors: K
authors: K
authors: Ghobadi
authors: A
authors: A
authors: Sadighi
authors: A A
authors: AA
authors: Abolfathi
authors: N D
authors: ND
authors: Nader
keywords: C-reactive protein (CRP); cardiopulmonary bypass; coronary artery bypass grafting; off-pump; on-pump; tumor necrotizing factor-alpha (TNF-alpha)