title: A motivational interviewing intervention to PREvent PAssive Smoke Exposure (PREPASE) in children with a high risk of asthma: design of a randomised controlled trial.
abstract: BACKGROUND
  Especially children at risk for asthma are sensitive to the detrimental health effects of passive smoke (PS) exposure, like respiratory complaints and allergic sensitisation. Therefore, effective prevention of PS exposure in this group of vulnerable children is important. Based on previous studies, we hypothesized that an effective intervention program to prevent PS exposure in children is possible by means of a motivational interviewing tailored program with repeated contacts focussing on awareness, knowledge, beliefs (pros/cons), perceived barriers and needs of parents, in combination with feedback about urine cotinine levels of the children. The aim of the PREPASE study is to test the effectiveness of such an intervention program towards eliminating or reducing of PS exposure in children at risk for asthma. This article describes the protocol of the PREPASE study.
  
  
  METHODS
  The study is a one-year follow-up randomized controlled trial. Families with children (0-13 years of age) having an asthma predisposition who experience PS exposure at home are randomized into an intervention group receiving an intervention or a control group receiving care as usual. The intervention is given by trained research assistants. The intervention starts one month after a baseline measurement and takes place once per month for an hour during six home based counselling sessions. The primary outcome measure is the percentage of families curtailing PS exposure in children (parental report verified with the urine cotinine concentrations of the children) after 6 months. The secondary outcome measures include: household nicotine level, the child's lung function, airway inflammation and oxidative stress, presence of wheezing and questionnaires on respiratory symptoms, and quality of life. A process evaluation is included. Most of the measurements take place every 3 months (baseline and after 3, 6, 9 and 12 months of study).
  
  
  CONCLUSIONS
  The PREPASE study incorporates successful elements of previous interventions and may therefore be very promising. If proven effective, the intervention will benefit the health of children at risk for asthma and may also create opportunity to be tested in other population.
  
  
  BACKGROUND
  NTR2632.
authors: Department of Paediatric Pulmonology, Maastricht University Medical Centre (MUMC+) / CAPHRI School for Public Health and Primary Care, P.O. Box 616, Maastricht, MD 6200, The Netherlands. sasha.hutchinson@maastrichtuniversity.nl
authors: Sasha G
authors: SG
authors: Hutchinson
authors: Ilse
authors: I
authors: Mesters
authors: Gerard
authors: G
authors: van Breukelen
authors: Jean Wm
authors: JW
authors: Muris
authors: Frans Jm
authors: FJ
authors: Feron
authors: S Katharine
authors: SK
authors: Hammond
authors: Constant P
authors: CP
authors: van Schayck
authors: Edward
authors: E
authors: Dompeling
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure / Q000517:prevention & control*; D005500:Follow-Up Studies; D006293:Health Promotion / Q000379:methods*; D006801:Humans; D007223:Infant; D062405:Motivational Interviewing; D010290:Parents / Q000523:psychology*; D015397:Program Evaluation; D012107:Research Design; D018570:Risk Assessment; D012907:Smoking / Q000523:psychology*; D016540:Smoking Cessation / Q000706:statistics & numerical data; D000074606:Smoking Prevention; D013997:Time Factors; D014028:Tobacco Smoke Pollution / Q000517:prevention & control*
chemical_list: D014028:Tobacco Smoke Pollution