title: Synthesis of β-halo-pyrrolidinones through a tandem sequence of 5-endo halolactamization and C-H oxidative functionalization.
abstract: A tandem sequence of 5-endo halolactamization and direct C-H oxidative functionalization is described. A range of β-halo-pyrrolidinones can be efficiently synthesized using this method, making it an excellent approach for constructing natural products containing pyrrolidinones.
authors: Tianjin Key Laboratory for Modern Drug Delivery & High Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, P. R. China. tangyu114@gmail.com
authors: Yu
authors: Y
authors: Tang
authors: Mingcan
authors: M
authors: Lv
authors: Xiaofan
authors: X
authors: Liu
authors: Hejing
authors: H
authors: Feng
authors: Liwei
authors: L
authors: Liu
mesh_terms: D002384:Catalysis; D006842:Hydrocarbons, Brominated / Q000138:chemical synthesis* / Q000737:chemistry; D006847:Hydrocarbons, Iodinated / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011760:Pyrrolidinones / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D006842:Hydrocarbons, Brominated; D006847:Hydrocarbons, Iodinated; D011760:Pyrrolidinones