title: Vertebral artery dissection associated with sildenafil abuse.
abstract: We present a 49-year-old male who suffered a cerebellar infarction due to a vertebral artery dissection. The patient had taken sildenafil daily for at least 2 years for sexual enhancement. There was no sexual intercourse or traumatic event prior to symptom onset. Sildenafil intake has been associated with aortic dissection and, in the light of this report, we suggest that chronic sildenafil intake could be a risk factor for arterial dissection.
authors: Department of Neurology, University Clinic Freiburg, Germany. Rick.Dersch@uniklinik-freiburg.de
authors: Rick
authors: R
authors: Dersch
authors: Constantin
authors: C
authors: Anastasopoulos
authors: Claudia
authors: C
authors: Hader
authors: Oliver
authors: O
authors: Stich
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage / Q000494:pharmacology; D002544:Cerebral Infarction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D000077144:Clopidogrel; D006493:Heparin / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010879:Piperazines / Q000009:adverse effects*; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage / Q000494:pharmacology; D011687:Purines / Q000009:adverse effects; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000009:adverse effects*; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000494:pharmacology; D016896:Treatment Outcome; D014463:Ultrasonography; D014665:Vasodilator Agents / Q000009:adverse effects*; D020217:Vertebral Artery Dissection / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000925:Anticoagulants; D010879:Piperazines; D010975:Platelet Aggregation Inhibitors; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D006493:Heparin; D000077144:Clopidogrel; D000068677:Sildenafil Citrate; D013988:Ticlopidine