title: Prospective risk factors for suicide attempts in a treated sample of patients with borderline personality disorder.
abstract: OBJECTIVE
  People with borderline personality disorder (BPD) are at high risk for attempting suicide. There are some data to suggest that risk factors for suicide attempts change over time. We conducted a prospective cohort study to examine risk factors for suicide attempts in a treated sample of patients with BPD.
  
  
  METHODS
  One hundred eighty participants with BPD were followed over a year-long course of dialectical behaviour therapy or general psychiatric management and then for 2 more years in naturalistic follow-up. Participants were assessed for suicidal and self-injurious behaviours at baseline, every 4 months over the 1-year treatment phase, and every 6 months over a 2-year follow-up period. Participants were classified as suicide or non-suicide attempters based on their behaviour at the end of the 1-year treatment phase and after the 2-year follow-up period. Groups were then compared on baseline clinical and demographic variables.
  
  
  RESULTS
  Nearly 26% of participants made a suicide attempt during the 1-year treatment phase, while 16.7% reported a suicide attempt over the 2-year follow-up period. Baseline number of suicide attempts during the 4 months prior to study and severity of childhood sexual abuse predicted suicide attempts during the treatment year. Similarly, baseline suicide attempts, severity of childhood sexual abuse, and number of hospitalizations in the 4 months prior to study entry predicted suicide attempts during the 2-year follow-up.
  
  
  CONCLUSIONS
  Risk factors for suicide attempts in this treated sample of patients with BPD were fairly stable, largely non-modifiable, and unrelated to psychopathology or psychosocial functioning at baseline.
authors: Department of Psychiatry, The University of Western Ontario, London, Ontario, Canada. paul.links@lhsc.on.ca
authors: Paul S
authors: PS
authors: Links
authors: Nathan J
authors: NJ
authors: Kolla
authors: Tim
authors: T
authors: Guimond
authors: Shelley
authors: S
authors: McMain
mesh_terms: D000328:Adult; D000367:Age Factors; D001521:Behavior Therapy / Q000379:methods / Q000706:statistics & numerical data; D001883:Borderline Personality Disorder / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D002170:Canada / Q000453:epidemiology; D002648:Child; D002650:Child Abuse, Sexual / Q000523:psychology / Q000706:statistics & numerical data*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D017063:Outcome Assessment, Health Care; D011446:Prospective Studies; D011599:Psychopathology; D012044:Regression Analysis; D018570:Risk Assessment; D012307:Risk Factors; D016728:Self-Injurious Behavior / Q000453:epidemiology / Q000209:etiology; D012737:Sex Factors; D012959:Socioeconomic Factors; D013406:Suicide, Attempted / Q000523:psychology / Q000706:statistics & numerical data