title: [Bone metabolism, renal function and immune structure in prostate cancer. Our experience].
abstract: Relation studies between bone and immune system converge in recent years in osteoimmunology chapter. It has been suggested that prostate cancer cells may alter bone homeostasis, renal function and the immune system. The aim of this paper is to evaluate bone metabolism, renal function and immune process in prostate cancer patients versus control. Patients with prostate malignancy and bone metastases showed a condition of hypocalcemia and hypophosphatemia associated with increased bone anabolism and lymphopenia, suggesting a possible correlation between bone metabolism and immune context in prostate cancer.
authors: Dipartimento di Medicina e Scienze dell'Invecchiamento, Dipartimento di Scienze Biomediche, Università Gabriele d'Annunzio, Chieti. docveronica@gmail.com
authors: Simona
authors: S
authors: Di Francesco
authors: Raffaele Lanfranco
authors: RL
authors: Tenaglia
mesh_terms: D000230:Adenocarcinoma / Q000097:blood* / Q000276:immunology / Q000556:secondary; D000368:Aged; D000369:Aged, 80 and over; D000469:Alkaline Phosphatase / Q000097:blood; D015415:Biomarkers; D014408:Biomarkers, Tumor; D001772:Blood Cell Count; D001859:Bone Neoplasms / Q000097:blood / Q000556:secondary; D001862:Bone Resorption / Q000209:etiology; D001842:Bone and Bones / Q000378:metabolism*; D003404:Creatinine / Q000097:blood; D018450:Disease Progression; D005919:Glomerular Filtration Rate; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology; D017674:Hypophosphatemia / Q000209:etiology; D007668:Kidney / Q000503:physiopathology*; D008231:Lymphopenia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000097:blood / Q000276:immunology; D011470:Prostatic Hyperplasia / Q000097:blood / Q000276:immunology; D011471:Prostatic Neoplasms / Q000097:blood* / Q000276:immunology; D012189:Retrospective Studies
chemical_list: D015415:Biomarkers; D014408:Biomarkers, Tumor; D003404:Creatinine; D000469:Alkaline Phosphatase