title: Multidisciplinary management of gastric cancer.
abstract: Treatment of gastric cancer involves a multidisciplinary approach to achieve long-term outcome, including surgery, chemotherapy, and radiation therapy. Most patients present with advanced disease and are not candidates for a curative approach. Palliative chemotherapy is recommended for symptom control and for short-term advances in survival. Surgery combined with different chemotherapy and chemoradiation options improves survival. Initial studies focused on adjuvant chemoradiation and showed improved survival. More recent trials have demonstrated that perioperative chemotherapy before and after surgery provides a survival advantage. Such an approach may also downstage marginal patients who can then be selected to undergo curative resection and complete adjuvant chemotherapy.
authors: Department of Medical Oncology, Helen F. Graham Cancer Center, Christiana Care Hospital, Newark, DE 19713, USA.
authors: Jamal G
authors: JG
authors: Misleh
authors: Peter
authors: P
authors: Santoro
authors: Jonathon F
authors: JF
authors: Strasser
authors: Joseph J
authors: JJ
authors: Bennett
mesh_terms: D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D006801:Humans; D010348:Patient Care Team; D017410:Practice Guidelines as Topic; D013274:Stomach Neoplasms / Q000628:therapy*