title: Vascular diameter measurement in CT angiography: comparison of model-based iterative reconstruction and standard filtered back projection algorithms in vitro.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the performance of model-based iterative reconstruction (MBIR) in measurement of the inner diameter of models of blood vessels and compare performance between MBIR and a standard filtered back projection (FBP) algorithm.
  
  
  METHODS
  Vascular models with wall thicknesses of 0.5, 1.0, and 1.5 mm were scanned with a 64-MDCT unit and densities of contrast material yielding 275, 396, and 542 HU. Images were reconstructed images by MBIR and FBP, and the mean diameter of each model vessel was measured by software automation. Twenty separate measurements were repeated for each vessel, and variance among the repeated measures was analyzed for determination of measurement error. For all nine model vessels, CT attenuation profiles were compared along a line passing through the luminal center on axial images reconstructed with FBP and MBIR, and the 10-90% edge rise distances at the boundary between the vascular wall and the lumen were evaluated.
  
  
  RESULTS
  For images reconstructed with FBP, measurement errors were smallest for models with 1.5-mm wall thickness, except those filled with 275-HU contrast material, and errors grew as the density of the contrast material decreased. Measurement errors with MBIR were comparable to or less than those with FBP. In CT attenuation profiles of images reconstructed with MBIR, the 10-90% edge rise distances at the boundary between the lumen and vascular wall were relatively short for each vascular model compared with those of the profile curves of FBP images.
  
  
  CONCLUSIONS
  MBIR is better than standard FBP for reducing reconstruction blur and improving the accuracy of diameter measurement at CT angiography.
authors: Department of Radiology, Saitama Red Cross Hospital, 8-3-33 Kamiochiai, Chuo-ku, Saitama 338-0001, Japan. shig.suz@gmail.com
authors: Shigeru
authors: S
authors: Suzuki
authors: Haruhiko
authors: H
authors: Machida
authors: Isao
authors: I
authors: Tanaka
authors: Eiko
authors: E
authors: Ueno
mesh_terms: D000465:Algorithms; D000792:Angiography / Q000295:instrumentation / Q000379:methods*; D003198:Computer Simulation; D006801:Humans; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging; D011856:Radiographic Image Enhancement / Q000379:methods; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods*