title: Two acute myeloblastic leukemia cases concomitant with hemophagocytic lymphohistiocytosis and review of the literature.
abstract: We present two patients with acute myeloblastic leukemia (FAB AML-M7 and AML-M2) complicated by hemophagocytic lymphohistiocytosis (HLH) and relevant literature review. To our knowledge, our first case is the first and youngest patient having AML-M7 associated with HLH reported in the literature. Our cases and cases in the literature highlight the high mortality rate of leukemia associated with HLH and the need for further investigation for the most appropriate therapy.
authors: Dr. A.Y. Ankara Oncology Training and Research Hospital, Division of Pediatric Hematology, Ankara, Turkey.
authors: Arzu
authors: A
authors: Akyay
authors: Tiraje
authors: T
authors: Celkan
authors: Gülşen
authors: G
authors: Iskender
authors: Ajlan
authors: A
authors: Tükün
authors: Cihat
authors: C
authors: Ogan
authors: Lale
authors: L
authors: Olcay
mesh_terms: D002648:Child; D017809:Fatal Outcome; D005260:Female; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D007223:Infant; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000473:pathology; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000473:pathology; D008533:Megakaryocytes / Q000473:pathology