title: In patients with severe sepsis, does a single dose of etomidate to facilitate intubation increase mortality?
abstract: Currently, single-dose etomidate has not been shown to cause increased mortality in septic patients requiring intubation; however, sufficiently powered randomized trials are required before definitive conclusions can be drawn.
authors: Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
authors: Benton R
authors: BR
authors: Hunter
authors: Jonathan
authors: J
authors: Kirschner
mesh_terms: D005045:Etomidate / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D007442:Intubation, Intratracheal / Q000009:adverse effects / Q000379:methods*; D018805:Sepsis / Q000401:mortality / Q000628:therapy*
chemical_list: D006993:Hypnotics and Sedatives; D005045:Etomidate