title: Coronary computed tomography angiography for selecting coronary artery bypass graft surgery candidates.
abstract: BACKGROUND
  There have been limited reports on the diagnostic performance and prognostic value of coronary computed tomography angiography (CCTA) for selecting coronary artery bypass graft (CABG) candidates.
  
  
  METHODS
  There were 1,018 patients with suspected coronary artery disease who underwent 64-slice multidetector CCTA between July 2009 and January 2010. Of them, we excluded 324 patients who denied further treatment (n=7), who were lost for unidentified reasons (n=107), or who were transferred to local clinics (n=210). The total analysis cohort consisted of 694 patients. We established eligible CABG criteria defined as three-vessel disease, left main coronary disease, and left main coronary artery equivalent disease. Diagnostic performance was determined using conventional coronary angiography as the reference standard. For assessment of the prognostic utility of CCTA, electronic medical records were reviewed to screen for the occurrence of a major adverse cardiac event, defined as cardiac death, nonfatal myocardial infarction, or revascularization.
  
  
  RESULTS
  The overall sensitivity, specificity, positive predictive value, and negative predictive value of CCTA for the selection of CABG candidates were 83.3%, 96.2%, 90.9%, and 92.7%, respectively. The presence of CABG criteria on CCTA was an independent prognostic factor for predicting a major adverse cardiac event (hazard ratio, 12.508; 95% confidence interval, 7.353 to 21.278; p<0.0001).
  
  
  CONCLUSIONS
  We found CCTA had a high diagnostic performance for selecting CABG candidates and predicted major adverse cardiac events in CABG candidates referred for CCTA owing to suspected coronary artery disease.
authors: Department of Radiology, Yonsei University College of Medicine, Severance Hospital, Seoul, Republic of Korea.
authors: Soo-Yeon
authors: SY
authors: Kim
authors: Hye-Jeong
authors: HJ
authors: Lee
authors: Young Jin
authors: YJ
authors: Kim
authors: Jin
authors: J
authors: Hur
authors: Yoo Jin
authors: YJ
authors: Hong
authors: Kyung-Jong
authors: KJ
authors: Yoo
authors: Hyuk-Jae
authors: HJ
authors: Chang
authors: Tae Hoon
authors: TH
authors: Kim
authors: Kyung-Hwa
authors: KH
authors: Han
authors: ByoungWook
authors: B
authors: Choi
mesh_terms: D017023:Coronary Angiography / Q000379:methods*; D001026:Coronary Artery Bypass / Q000379:methods*; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D018579:Patient Selection; D011237:Predictive Value of Tests; D011379:Prognosis; D012372:ROC Curve; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*