title: Iodobenzene catalyzed C-H amination of N-substituted amidines using m-chloroperbenzoic acid.
abstract: The oxidative C-H amination of N"-aryl-N'-tosyl/N'-methylsulfonylamidines and N,N'-bis(aryl)amidines has been accomplished using iodobenzene as a catalyst to furnish 1,2-disubstituted benzimidazoles in the presence of mCPBA as a terminal oxidant at room temperature. The reaction is general, and the target products can be obtained in moderate to high yields.
authors: Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati-781039, India.
authors: Santhosh Kumar
authors: SK
authors: Alla
authors: Rapolu Kiran
authors: RK
authors: Kumar
authors: Pradeep
authors: P
authors: Sadhu
authors: Tharmalingam
authors: T
authors: Punniyamurthy
mesh_terms: D000578:Amidines / Q000737:chemistry*; D000586:Amination; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D002723:Chlorobenzoates / Q000737:chemistry*; D020650:Combinatorial Chemistry Techniques; D007462:Iodobenzenes / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D000578:Amidines; D001562:Benzimidazoles; D002723:Chlorobenzoates; D007462:Iodobenzenes; C031905:iodobenzene; C000433:3-chloroperbenzoic acid