title: A new class of plant lipid is essential for protection against phosphorus depletion.
abstract: Phosphorus supply is a major factor responsible for reduced crop yields. As a result, plants utilize various adaptive mechanisms against phosphorus depletion, including lipid remodelling. Here we report the involvement of a novel plant lipid, glucuronosyldiacylglycerol, against phosphorus depletion. Lipidomic analysis of Arabidopsis plants cultured in phosphorus-depleted conditions revealed inducible accumulation of glucuronosyldiacylglycerol. Investigation using a series of sulfolipid sulfoquinovosyldiacylglycerol synthesis-deficient mutants of Arabidopsis determined that the biosynthesis of glucuronosyldiacylglycerol shares the pathway of sulfoquinovosyldiacylglycerol synthesis in chloroplasts. Under phosphorus-depleted conditions, the Arabidopsis sqd2 mutant, which does not accumulate either sulfoquinovosyldiacylglycerol or glucuronosyldiacylglycerol, was the most severely damaged of three sulfoquinovosyldiacylglycerol-deficient mutants. As glucuronosyldiacylglycerol is still present in the other two mutants, this result indicates that glucuronosyldiacylglycerol has a role in the protection of plants against phosphorus limitation stress. Glucuronosyldiacylglycerol was also found in rice, and its concentration increased significantly following phosphorus limitation, suggesting a shared physiological significance of this novel lipid against phosphorus depletion in plants.
authors: Metabolomic Function Research Group, RIKEN Plant Science Center, Yokohama 230-0045, Japan.
authors: Yozo
authors: Y
authors: Okazaki
authors: Hitomi
authors: H
authors: Otsuki
authors: Tomoko
authors: T
authors: Narisawa
authors: Makoto
authors: M
authors: Kobayashi
authors: Satoru
authors: S
authors: Sawai
authors: Yukiko
authors: Y
authors: Kamide
authors: Miyako
authors: M
authors: Kusano
authors: Toshio
authors: T
authors: Aoki
authors: Masami Yokota
authors: MY
authors: Hirai
authors: Kazuki
authors: K
authors: Saito
mesh_terms: D017360:Arabidopsis / Q000201:enzymology / Q000254:growth & development / Q000378:metabolism*; D053898:Biosynthetic Pathways / Q000187:drug effects; D002853:Chromatography, Liquid; D016002:Discriminant Analysis; D006017:Glycolipids / Q000096:biosynthesis / Q000737:chemistry / Q000172:deficiency / Q000378:metabolism*; D016018:Least-Squares Analysis; D050356:Lipid Metabolism / Q000187:drug effects; D055432:Metabolomics; D008954:Models, Biological; D009154:Mutation / Q000235:genetics; D012275:Oryza / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D010641:Phenotype; D010758:Phosphorus / Q000172:deficiency* / Q000494:pharmacology; D018515:Plant Leaves / Q000187:drug effects / Q000378:metabolism
chemical_list: D006017:Glycolipids; C014573:glucuronosyl diacylglycerol; C013694:sulfoquinovosyl diglyceride; D010758:Phosphorus