title: The coming age of complete, accurate, and ubiquitous proteomes.
abstract: High-resolution mass spectrometry (MS)-based proteomics has progressed tremendously over the years. For model organisms like yeast, we can now quantify complete proteomes in just a few hours. Developments discussed in this Perspective will soon enable complete proteome analysis of mammalian cells, as well, with profound impact on biology and biomedicine.
authors: Max Planck Institute of Biochemistry, 82152 Martinsried, Germany. mmann@biochem.mpg.de
authors: Matthias
authors: M
authors: Mann
authors: Nils A
authors: NA
authors: Kulak
authors: Nagarjuna
authors: N
authors: Nagaraj
authors: Jürgen
authors: J
authors: Cox
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D019295:Computational Biology; D005656:Fungal Proteins / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D006801:Humans; D013058:Mass Spectrometry; D020543:Proteome / Q000032:analysis* / Q000737:chemistry / Q000302:isolation & purification; D040901:Proteomics; D015003:Yeasts / Q000737:chemistry*
chemical_list: D005656:Fungal Proteins; D020543:Proteome