title: Vitamin D and heart.
abstract: The authors briefly review the biological effects of vitamin D on the heart and discuss the experimental and clinical studies related to the potential protective effect of vitamin D on the cardiovascular system. Experimental and observational studies in man strongly suggest that vitamin D supplementation can benefit heart failure patients and improve cardiovascular health in the population. However, presently there are limited randomized controlled studies. The authors highlight the hypothesis that vitamin D-induced mechanisms activating calcium channels may represent a novel target for therapy in patients with heart failure.
authors: Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
authors: Marcello
authors: M
authors: Camici
authors: Fabio
authors: F
authors: Galetta
authors: Ferdinando
authors: F
authors: Franzoni
authors: Angelo
authors: A
authors: Carpi
authors: Farhad
authors: F
authors: Zangeneh
mesh_terms: D000818:Animals; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D032383:Myocytes, Cardiac / Q000502:physiology; D018167:Receptors, Calcitriol / Q000502:physiology; D014807:Vitamin D / Q000627:therapeutic use*; D014808:Vitamin D Deficiency / Q000503:physiopathology; D014815:Vitamins / Q000627:therapeutic use*
chemical_list: D018167:Receptors, Calcitriol; D014815:Vitamins; D014807:Vitamin D