title: Detection of placenta elasticity modulus by quantitative real-time shear wave imaging.
abstract: OBJECTIVE
  To explore the clinical values in detecting the placental elastic modulus using real-time quantitative shear wave elasticity imaging.
  
  
  METHODS
  A total of 30 women in the late pregnancy stage without complications and having normal, single pregnancies, as well as normal fetal growth, amniotic fluid index, and anterior placenta were selected. A real-time elasticity imaging shear wave ultrasonic diagnostic apparatus was used to randomly select regions of interest at the central and edge of the placenta. The elastography imaging mode was launched to measure the elasticity of the elastic modulus of these placental parts. A total of 15 measured values were obtained at the placental center and edge for each pregnancy case. Umbilical artery and uterine artery pulsatility index (PI) values for 18 cases were also randomly measured.
  
  
  RESULTS
  The average value of 30 placental edges of the elastic modulus (n = 15) was (7.60 +/- 1.71) kPa. The average value of the 30 placental central elastic modulus (n = 15 ) was (7.84 +/- 1.68) kPa. No significant difference was observed between placenta central and edge elastic modulus. The PI mean value of umbilical artery in 18 cases was 0.94, whereas the average PI values of the uterine artery was 0.83. No linear correlation was found among the elastic modulus, the placental uterine artery PI values, and the umbilical artery PI values (p > 0.05).
  
  
  CONCLUSIONS
  No difference between the placental center of normal pregnancies and the edge of the elastic modulus was detected. The elastic modulus of the placenta could be obtained in the best position. The placenta varied greatly between elastic modulus. No correlation was found between the placental elastic modulus, the uterine artery, and umbilical artery PI values. Real-time shear wave elasticity imaging technology can provide morphological evidence of placental function, which may emerge as a new clinical assessment approach.
authors: Department of Fetal Medicine, the First Affiliated Hospital of Jinan University, Guangzhou China. mood0904@yahoo.com.cn
authors: W J
authors: WJ
authors: Li
authors: Z T
authors: ZT
authors: Wei
authors: R L
authors: RL
authors: Yan
authors: Y L
authors: YL
authors: Zhang
mesh_terms: D000328:Adult; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D010920:Placenta / Q000503:physiopathology*; D010925:Placental Function Tests / Q000379:methods*; D011247:Pregnancy; D011673:Pulsatile Flow; D016216:Ultrasonography, Prenatal / Q000379:methods*; D014469:Umbilical Arteries / Q000000981:diagnostic imaging / Q000502:physiology