title: CTLM as an adjunct to mammography in the diagnosis of patients with dense breast.
abstract: OBJECTIVE
  The purpose was to evaluate the utility of computed tomographic laser mammography (CTLM) as an adjunct examination to mammography in women with dense breast tissue.
  
  
  METHODS
  We retrospectively compared the findings of mammography, CTLM, and adjunct CTLM to mammography with pathology of 155 women scheduled for biopsy or surgery.
  
  
  RESULTS
  Positive lesions were observed more significantly in malignant than benign lesions. The sensitivity of mammography vs. mammography+CTLM was 34.4% vs. 81.57% among extremely dense breasts and 68.29% vs. 95.34% among heterogeneously dense breasts.
  
  
  CONCLUSIONS
  CTLM could distinguish benign lesions from malignant lesions and is not affected by breast density.
authors: Radiology Department, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Breast Cancer Prevention and Therapy of the Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, PR China.
authors: Jin
authors: J
authors: Qi
authors: Zhaoxiang
authors: Z
authors: Ye
mesh_terms: D000328:Adult; D000368:Aged; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D016009:Chi-Square Distribution; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007834:Lasers; D008327:Mammography; D008875:Middle Aged; D011237:Predictive Value of Tests; D011857:Radiographic Image Interpretation, Computer-Assisted; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*