title: Rapid recovery from acute liver failure secondary to pancreatoduodenectomy-related non-alcoholic steatohepatitis.
abstract: This report describes a case of liver failure secondary to pancreatoduodenectomy and rapid recovery following treatment. A 68-year-old woman with cancer on the ampulla of Vater underwent surgery for pancreatoduodenectomy. The patient developed liver failure 3 months postsurgically. She was hospitalized after presenting with jaundice, hypoalbuminemia and decreased serum zinc. Computed tomography (CT) of the abdomen showed a reduction in CT attenuation values postoperatively. We suspected fatty liver due to impaired absorption caused by pancreatoduodenectomy. We initiated treatment with branched-chain amino acids and a zinc formulation orally. Trace elements were administered intravenously. Two months after treatment, there was a noticeable improvement in CT findings. The patient's jaundice and hypoalbuminemia prompted a liver biopsy, which led to a diagnosis of non-alcoholic steatohepatitis.
authors: Division of Gastroenterology and Hepatology, Nihon University School of Medicine, Tokyo, Japan.
authors: Kazushige
authors: K
authors: Nirei
authors: Norikazu
authors: N
authors: Ogihara
authors: Wataru
authors: W
authors: Kawamura
authors: Woodea
authors: W
authors: Kang
authors: Mitsuhiko
authors: M
authors: Moriyama
keywords: Fatty liver; Liver failure; Non-alcoholic steatohepatitis; Pancreatoduodenectomy; Zinc