title: A sensitive ratiometric fluorescent sensor for zinc(II) with high selectivity.
abstract: A new fluorescent Zn²⁺ chemosensor (P1) based on a functionalized porphyrin was synthesized and characterized. P1 displayed dramatic ratiometric variations in absorption and fluorescent emission spectra upon exposure to Zn²⁺ due to the formation of a 1:1 Zn²⁺/P1 complex. The sensor also exhibited high selectivity and sensitivity toward Zn²⁺ over other common metal ions in the physiological pH range with a detection limit of 1.8 mM. The sensor showed fast response times and excellent reproducibility, thus confirming its potential applicability as a fluorescent sensor for Zn²⁺ sensing.
authors: School of Medicine, Zhejiang University City College, Hangzhou 310015, Zhejiang, China. lvyy@zucc.edu.cn
authors: Yuanyuan
authors: Y
authors: Lv
authors: Mingda
authors: M
authors: Cao
authors: Jiakai
authors: J
authors: Li
authors: Junbo
authors: J
authors: Wang
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D005453:Fluorescence; D057230:Limit of Detection; D011166:Porphyrins / Q000737:chemistry*; D015032:Zinc / Q000302:isolation & purification*
chemical_list: D011166:Porphyrins; D015032:Zinc