title: Assessing new strategies for TB diagnosis in low- and middle-income countries.
abstract: In this manuscript, we report the current situation of tuberculosis globally and in Brazil, the need for new strategies toward tuberculosis control, focusing on new diagnostic technologies. Critical comments are given on the state of the art regarding the evaluation of new health technologies, degree of scientific evidence needed, evaluation of clinical impact, cost-effectiveness of incorporation into the health system and the social impact.
authors: Rede TB, Rio de Janeiro, RJ, Brazil. kritskia@gmail.com
authors: Afrânio
authors: A
authors: Kritski
authors: Paula I
authors: PI
authors: Fujiwara
authors: Maria Armanda
authors: MA
authors: Vieira
authors: Antonio Ruffino
authors: AR
authors: Netto
authors: Martha Maria
authors: MM
authors: Oliveira
authors: Gisele
authors: G
authors: Huf
authors: S
authors: S
authors: Bertel Squire
mesh_terms: D001431:Bacteriological Techniques / Q000191:economics / Q000379:methods*; D003906:Developing Countries; D014943:Global Health; D006801:Humans; D017410:Practice Guidelines as Topic; D012196:Review Literature as Topic; D014376:Tuberculosis / Q000175:diagnosis* / Q000453:epidemiology