title: Diffusion-weighted imaging (DWI) signal intensity and distribution represent the amount of cancer cells and their distribution in primary lung cancer.
abstract: The aim of this study was to interpret diffusion-weighted imaging (DWI) signals in lung cancers. They were converted into several three-dimensional DWI signals patterns, which represent the degree of DWI signal intensity by height and the degree of distribution by area: flat, low elevation, irregular elevation, single-peak elevation, multiple-peak elevation, and nodular elevation. There were 39 adenocarcinomas and 21 squamous cell carcinomas. Three-dimensional DWI signals decreased significantly in order of cell differentiation. Tumor cellular densities were increased according to the increase in three-dimensional DWI signals. DWI signal intensity and distribution can represent the amount of cancer cells and their distribution in the carcinoma.
authors: Department of Thoracic Surgery, Kanazawa Medical University, Ishikawa, Japan. usuda@kanazawa-med.ac.jp
authors: Katsuo
authors: K
authors: Usuda
authors: Xi-Tong
authors: XT
authors: Zhao
authors: Motoyasu
authors: M
authors: Sagawa
authors: Hirokazu
authors: H
authors: Aikawa
authors: Masakatsu
authors: M
authors: Ueno
authors: Makoto
authors: M
authors: Tanaka
authors: Yuichiro
authors: Y
authors: Machida
authors: Munetaka
authors: M
authors: Matoba
authors: Yoshimichi
authors: Y
authors: Ueda
authors: Tsutomu
authors: T
authors: Sakuma
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D021621:Imaging, Three-Dimensional; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18