title: Lymphoproliferative neoplasms of the lung: a review.
abstract: BACKGROUND
  Diagnosis and classification of lymphomas are based on the morphologic, immunologic, and genetic features that the lesional cells share with their normal B and T lymphocyte counterparts. Primary pulmonary lymphomas account for 0.3% of primary lung neoplasms and less than 0.5% of all lymphomas.
  
  
  OBJECTIVE
  To describe and summarize the clinical and histopathologic features of the primary pulmonary lymphoma and secondary involvement of the lung by lymphoma.
  
  
  METHODS
  Peer-reviewed published literature and personal experience.
  
  
  CONCLUSIONS
  Diagnosis of clonal lymphoid proliferations in the lung has evolved owing to the greater utility of molecular and flow cytometric analysis of tissue. Further studies are needed to best define the clinical and prognostic features, as well as search for targeted therapy for these patients with rare neoplasms.
authors: Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.
authors: Josette
authors: J
authors: William
authors: Daina
authors: D
authors: Variakojis
authors: Anjana
authors: A
authors: Yeldandi
authors: Kirtee
authors: K
authors: Raparia
mesh_terms: D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008223:Lymphoma / Q000473:pathology*