title: Successful autologous cord blood transplantation in a child with acquired severe aplastic anemia.
abstract: Over 400 cases of pediatric SAA occur annually in the United States. A growing number of children with SAA may have had their stem cells harvested through cord blood collection. We describe a nine-yr-old male with SAA treated successfully with an autologous cord blood transplant following immunoablative chemotherapy. With the increasing number of people cryopreserving autologous cord blood, the use of autologous cord blood in the treatment of SAA might be considered as initial therapy. This case serves to discuss approaches to preparative therapy as well as the potential complications in this growing cohort of patients.
authors: Division of Hematology, CHOC Children's Hospital, Orange, CA 92868, USA. dbuchbinder@choc.org
authors: David
authors: D
authors: Buchbinder
authors: Loah
authors: L
authors: Hsieh
authors: Geetha
authors: G
authors: Puthenveetil
authors: Amit
authors: A
authors: Soni
authors: Jill
authors: J
authors: Stites
authors: Van
authors: V
authors: Huynh
authors: Ivan
authors: I
authors: Kirov
authors: Steve
authors: S
authors: Neudorf
authors: Elyssa
authors: E
authors: Rubin
authors: Leonard
authors: L
authors: Sender
authors: Lilibeth
authors: L
authors: Torno
authors: David
authors: D
authors: Margolis
authors: Richard
authors: R
authors: Childs
authors: Theodore
authors: T
authors: Moore
authors: Diane
authors: D
authors: Nugent
mesh_terms: D000741:Anemia, Aplastic / Q000628:therapy*; D001771:Blood Banks; D002648:Child; D036101:Cord Blood Stem Cell Transplantation / Q000379:methods*; D015925:Cryopreservation; D005312:Fetal Blood / Q000166:cytology; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D008297:Male; D019172:Transplantation Conditioning / Q000009:adverse effects; D014182:Transplantation, Autologous; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents