title: Synthesis of phthalazinones via palladium(II)-catalysed intramolecular oxidative C-H/C-H cross-coupling of N'-methylenebenzohydrazides.
abstract: A palladium(II)-catalysed intramolecular oxidative C-H/C-H cross-coupling of N'-methylenebenzohydrazides to phthalazin-1(2H)-ones has been developed. This cyclization is believed to mechanistically proceed via electrophilic ortho-palladation and subsequent C-arylation of the carbon-nitrogen double bond.
authors: Department of Applied Chemistry, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan. mtd@rs.tus.ac.jp
authors: Takanori
authors: T
authors: Matsuda
authors: Yuki
authors: Y
authors: Tomaru
authors: Yoshiya
authors: Y
authors: Matsuda
mesh_terms: D002384:Catalysis; D006834:Hydrazines / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D010793:Phthalazines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D006834:Hydrazines; D009942:Organometallic Compounds; D010793:Phthalazines; D010165:Palladium