title: A facile route to synthesize nanogels doped with silver nanoparticles.
abstract: In this work, we describe a simple method to prepare hybrid nanogels consisting of a biocompatible core-shell polymer host containing silver nanoparticles. First, the nanogels (NG, ~160 nm) containing a lysozyme rich core and a dextran rich shell, are prepared via Maillard and heat-gelation reactions. Second, silver nanoparticles (Ag NPs, ~5nm) are synthesizedin situin the NG solution without requiring additional reducing agents. This approach leads to stable Ag NPs located in the NG. Furthermore, we demonstrate that the amount of Ag NPs in the NG can be tuned by varying silver precursor concentration. Hybrid nanogels with silver nanoparticles have potential in antimicrobial, optical and therapeutic applications.
authors: Department of Materials Science, University of Pennsylvania, Philadelphia, US ; Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, US.
authors: M Carme Coll
authors: MC
authors: Ferrer
authors: Robert C
authors: RC
authors: Ferrier
authors: David M
authors: DM
authors: Eckmann
authors: Russell J
authors: RJ
authors: Composto
keywords: dextran; lysozyme; nanogel; silver nanoparticles