title: Lipophilic components from Fructus Viticis Negundo and their anti-tumor activities.
abstract: Two new triterpenoids, (24R/S)-24-hydroxy-3α 10α-epoxy-9-eip-cucurbita-25-ene (1a, b), as well as six known compounds (3-8), were isolated from the extraction of Fructus Viticis Negundo. Their structures were established on the basis of spectral analysis. In addition, all the compounds were tested for inhibitory effect against K-562 and A-549 cell lines.
authors: School of Pharmaceutical Sciences, Central South University, Changsha 410000, China.
authors: Danning
authors: D
authors: Huang
authors: Shan
authors: S
authors: Qing
authors: Guangyao
authors: G
authors: Zeng
authors: Yajing
authors: Y
authors: Wang
authors: Hong
authors: H
authors: Guo
authors: Jianbing
authors: J
authors: Tan
authors: Yingjun
authors: Y
authors: Zhou
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D005638:Fruit; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D020014:K562 Cells; D009369:Neoplasms / Q000188:drug therapy*; D008517:Phytotherapy; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use*; D020950:Vitex / Q000737:chemistry*
chemical_list: C584388:24-hydroxy-3alpha,10alpha-epoxy-9-eip-cucurbita-25-ene; D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal; D014315:Triterpenes