title: Is exercise-induced muscle damage susceptibility body segment dependent? Evidence for whole body susceptibility.
abstract: OBJECTIVE
  The current study examined serum CK activity following bench press (BP) and leg press (LP) exercise-induced muscle damage to evaluate agreement of subjects classification as either high (HiR) or normal responders (NoR) between upper and lower body muscle groups.
  
  
  METHODS
  Forty-two men performed two resistance exercise bouts (BP and LP) of four sets of maximum repetitions to concentric failure at 10RM, following a random design.
  
  
  RESULTS
  Fourteen subjects were classified as HiR after the BP and thirteen subjects after LP, while nine subjects were classified as HiR for both exercises. The analysis revealed good agreement (Kappa=0.528, with SE=0.137 and 95% confidence interval: from 0.259 to 0.798). Additionally, we found a significant moderate correlation (r=0.65, p<0.001) between CK peaks obtained following LP and BP.
  
  
  CONCLUSIONS
  Our results suggest that exercise-induced muscle damage susceptibility is a whole body characteristic and is not body segment dependent. Thus, it may be that genetic or systemic mechanisms explain individual variation in muscle damage susceptibility.
authors: Laboratory of Human Movement Studies - Universitary Fundation of Itaperuna - Itaperuna, RJ, Brazil. marcomachado1@gmail.com
authors: M
authors: M
authors: Machado
authors: L E
authors: LE
authors: Brown
authors: P
authors: P
authors: Augusto-Silva
authors: R
authors: R
authors: Pereira
mesh_terms: D000293:Adolescent; D000328:Adult; D001132:Arm / Q000502:physiology; D003402:Creatine Kinase / Q000097:blood*; D006801:Humans; D007866:Leg / Q000502:physiology; D008297:Male; D018482:Muscle, Skeletal / Q000201:enzymology* / Q000473:pathology*; D014891:Weight Lifting / Q000502:physiology*; D055815:Young Adult
chemical_list: D003402:Creatine Kinase