title: Early neurodevelopment and self-reported adolescent symptoms of depression and anxiety in a National Canadian Cohort Study.
abstract: OBJECTIVE
  Little is known about the mental health outcomes of young children who experience developmental delay. The objective of this study was to assess whether delay in attaining developmental milestones was related to depressive and anxious symptoms in adolescence.
  
  
  METHODS
  The sample included 3508 Canadian children who participated in a nationally representative prospective cohort study. The person most knowledgeable about the child reported on attainment of developmental milestones spanning several developmental domains at ages 2-3. The children were followed into adolescence and self-reported depressive and anxious symptoms were used from adolescents ages 12-13. An overall assessment of developmental milestones as well as a supplementary analysis of specific categories of developmental milestones was conducted.
  
  
  RESULTS
  Cohort members who displayed delayed developmental milestones in early childhood were more likely to experience higher levels of depressive and anxious symptoms as adolescents. However, there was no interaction between delayed developmental milestones and stressful life events. In the supplementary analysis, two developmental domains (self-care and speech/communication) were associated with higher levels of depressive and anxious symptoms in adolescence.
  
  
  CONCLUSIONS
  Delay in attainment of early developmental milestones is significantly associated with adolescent depressive and anxious symptoms.
authors: School of Public Health, University of Alberta, Edmonton, Canada.
authors: C Rebecca
authors: CR
authors: North
authors: T Cam
authors: TC
authors: Wild
authors: Lonnie
authors: L
authors: Zwaigenbaum
authors: Ian
authors: I
authors: Colman
mesh_terms: D000293:Adolescent; D001007:Anxiety / Q000453:epidemiology / Q000209:etiology*; D002170:Canada / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003863:Depression / Q000453:epidemiology / Q000209:etiology*; D002658:Developmental Disabilities / Q000150:complications*; D005500:Follow-Up Studies; D006801:Humans; D057566:Self Report