title: Quantitative transverse flow measurement using optical coherence tomography speckle decorrelation analysis.
abstract: We propose an inter-Ascan speckle decorrelation based method that can quantitatively assess blood flow normal to the direction of the optical coherence tomography imaging beam. To validate this method, we performed a systematic study using both phantom and in vivo animal models. Results show that our speckle analysis method can accurately extract transverse flow speed with high spatial and temporal resolution.
authors: Department of Electrical and Computer Engineering, The Johns Hopkins University, Baltimore, Maryland 21218, USA. xliu35@jhu.edu
authors: Xuan
authors: X
authors: Liu
authors: Yong
authors: Y
authors: Huang
authors: Jessica C
authors: JC
authors: Ramella-Roman
authors: Scott A
authors: SA
authors: Mathews
authors: Jin U
authors: JU
authors: Kang
mesh_terms: D000818:Animals; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D019047:Phantoms, Imaging; D041623:Tomography, Optical Coherence / Q000379:methods*