title: [Effect of Vimang in HIV/AIDS patients].
abstract: BACKGROUND
  the oxidative stress (OS) has been recognized as a co-factor of HIV infection evolution to AIDS condition.
  
  
  OBJECTIVE
  to evaluate the possible antioxidant effect and the impact on the functioning of several systems in the body, resulting in the toxicological safety of Vimang use.
  
  
  METHODS
  sixty eight HIV-seropositive patients were double-blind randomized in two groups; the first was supplied with Vimang during six months and the other with placebo. Redox condition and the biochemical indexes of the hematological, renal and hepatic functions were measured. Also, dietary intake was assessed through surveys administered for 7 days at the beginning and at the end of the study.
  
  
  RESULTS
  there were statistically significant differences between the groups regarding positive change in redox figures in Vimang group compared to those of the placebo group. No significant difference was found either in the evaluated dietary intake indexes or in the biochemical indexes of the renal, hematological and hepatic functions at the end of the study.
  
  
  CONCLUSIONS
  Vimang antioxidant effect was shown, without any toxic influence during the six month-study conducted in HIV/AIDS patients.
authors: Laboratorio de Farmacología Clínica, Instituto de Medicina Tropical Pedro Kouri, Ciudad de La Habana, Cuba. lgil@ipk.sld.cu
authors: Lizette
authors: L
authors: Gil del Valle
authors: Teresita
authors: T
authors: Serrano López
authors: Odalys
authors: O
authors: Calderón Fuentes
authors: Felicita
authors: F
authors: Núñez Sánchez
authors: Rolando D
authors: RD
authors: Tápanes Peraza
authors: Jorge
authors: J
authors: Pérez Avila
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy; D004311:Double-Blind Method; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D031022:Mangifera; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*
chemical_list: C501277:Mangifera indica extract; D010936:Plant Extracts