title: A novel multi-stage feature selection method for microarray expression data analysis.
abstract: With the development of genome research, finding method to classify cancer and detect biomarkers efficiently has become a challenging problem. In this paper, a novel multi-stage method for feature selection is proposed which considers all kinds of genes in the original gene set. The method eliminates the irrelevant, noisy and redundant genes and selects a subset of relevant genes at different stages. The proposed method is examined on microarray datasets of Leukemia, Prostate, Colon, Breast, Nervous and DLBCL by different classifiers and the best accuracies of the method in these datasets are 100%, 98.04%, 100%, 89.74%, 100% and 98.28%, respectively.
authors: College of Computer Science and Technology, Key Laboratory of Symbol Computation and Knowledge Engineering of the Ministry of Education, Jilin University, Changchun 130012, China. dwtyfx@hotmail.com
authors: Wei
authors: W
authors: Du
authors: Ying
authors: Y
authors: Sun
authors: Yan
authors: Y
authors: Wang
authors: Zhongbo
authors: Z
authors: Cao
authors: Chen
authors: C
authors: Zhang
authors: Yanchun
authors: Y
authors: Liang
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics / Q000378:metabolism; D020869:Gene Expression Profiling; D006801:Humans; D046228:Microarray Analysis / Q000379:methods*; D005810:Multigene Family; D009369:Neoplasms / Q000235:genetics*; D010363:Pattern Recognition, Automated
chemical_list: D014408:Biomarkers, Tumor