title: Open repair of descending thoracic aneurysms.
abstract: BACKGROUND
  Current strategies for operative treatment of a thoracic aortic aneurysm consist of open repair with surgical graft replacement or endovascular exclusion. To reduce mortality and morbidity of open repair, a multimodal approach has gradually evolved by maximizing organ protection.
  
  
  METHODS
  On a total of 1108 patients treated in our Center from 1993 for pathology involving the thoracic aorta, we reviewed the prospectively collected data of 194 consecutive patients who underwent open thoracic aortic aneurysm repair, 104 (54%) for degenerative aneurysms, 65 (34%) for dissections, 25 (12%) for other pattern of disease. Left Heart Bypass was used in 82% of cases, clamp and sew technique in 16%, hypotermic circulatory arrest in 2%.
  
  
  RESULTS
  Overall perioperative mortality was 4.1%. The rate of pulmonary complications was 8.8%. The rate of cardiac complications, i.e. new onset myocardial necrosis demonstrated by positive blood tests, was 6.2%. The rate of renal complications was 7.2%. Cerebrovascular accident, defined as a new neurologic deficit lasting more than 24 hours confirmed by imaging, occurred in 2.0% of patients. The rate of spinal cord ischemia, manifesting either as paraplegia or paraparesis, was 4.6%.
  
  
  CONCLUSIONS
  Mortality and morbidity rates of open thoracic aortic aneurysm repair are currently satisfactory especially in fit patients. In order to define surgical indications and the role of endovascular repair, consideration of age of the patient, comorbidity, symptoms, life expectancy, likely quality of life (if asymptomatic), aortic diameter, aneurysm morphology, aneurysm extent, suitability of landing zones, and operator experience are all distinctly relevant.
authors: Department of Vascular Surgery, Università Vita-Salute San Raffaele, Milan, Italy.
authors: R
authors: R
authors: Chiesa
authors: Y
authors: Y
authors: Tshomba
authors: E
authors: E
authors: Civilini
authors: E M
authors: EM
authors: Marone
authors: L
authors: L
authors: Bertoglio
authors: D
authors: D
authors: Baccellieri
authors: G
authors: G
authors: Coppi
authors: D
authors: D
authors: Logaldo
authors: G
authors: G
authors: Melissano
keywords: Marfan syndrome; aortic surgical graft; open aortic repair; thoracic aortic aneurysm; thoracic aortic dissection; type B aortic dissection