title: Synthesis of pyrrolo[2,1-a]isoquinolines by multicomponent 1,3-dipolar cycloaddition.
abstract: Pyrrolo[2,1-a]isoquinoline derivatives were synthesized by one-pot three-component reactions starting from isoquinoline, 2-bromoacetophenones and different non-symmetrical acetylenic dipolarophiles using 1,2-epoxypropane as solvent. The structure of the compounds was assigned by IR and NMR spectroscopy.
authors: Center of Organic Chemistry "C. D. Nenitzescu", Romanian Academy, Spl. Independentei 202B, Bucharest 060023, Romania. fdumitra@yahoo.com
authors: Florea
authors: F
authors: Dumitrascu
authors: Emilian
authors: E
authors: Georgescu
authors: Florentina
authors: F
authors: Georgescu
authors: Marcel Mirel
authors: MM
authors: Popa
authors: Denisa
authors: D
authors: Dumitrescu
mesh_terms: D000470:Alkaloids / Q000737:chemistry; D061565:Cycloaddition Reaction; D007546:Isoquinolines / Q000138:chemical synthesis / Q000737:chemistry*; D019906:Nuclear Magnetic Resonance, Biomolecular
chemical_list: D000470:Alkaloids; D007546:Isoquinolines