title: Transient leukaemia: leukaemia or leukaemoid? A diagnostic dilemma.
abstract: We report a case of a newborn male who had mongoloid slant and was hypotonic at birth. Routine investigations revealed leucocytosis (WBC > 70,000/cmm) with 50% blasts in peripheral blood film. Marrow examination confirmed the excess of blasts. Karyotyping revealed 47, XY + 21 chromosomes. Due to absence of clinical symptoms, the baby was kept on follow-up without treatment. Within 7 weeks, PBF and bone marrow findings returned to normal, and the child was diagnosed as having Transient leukaemia with Down syndrome.
authors: Department of Pathology, Pt. B.D. Sharma PGIMS, 2452, Sector-1, HUDA, Rohtak, 124001 India.
authors: Nisha
authors: N
authors: Marwah
authors: Shilpi
authors: S
authors: Modi
authors: Veena
authors: V
authors: Gupta
authors: Sumiti
authors: S
authors: Gupta
authors: Gajender
authors: G
authors: Singh
authors: Rajeev
authors: R
authors: Sen
keywords: Down syndrome; Transient leukaemia; Transient myeloproliferative disorder