title: How far you can trust c-ANCA?
abstract: The suspicion of a serious condition arises if a smoker is coughing and losing weight constantly. Serology and imaging are great options for diagnosis, but what is their specificity? A 62-year-old man presented with persistent cough, weight loss and hypoxia. A chest x-ray revealed bilateral interstitial infiltrates. Treatment with several antibiotics failed. Serological results showed antineutrophil cytoplasmic antibodies (c-ANCA) positivity. However, biopsy result indicated cryptogenic organising pneumonia. This case report discloses the differential diagnosis of c-ANCA positive interstitial lung disease in detail.
authors: Department of Internal Medicine, Creighton University Medical Center, Omaha, Nebraska, USA. kaanakturk@yahoo.com
authors: Halis Kaan
authors: HK
authors: Akturk
authors: Priyanka
authors: P
authors: Vashisht
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic / Q000097:blood*; D001706:Biopsy; D003371:Cough; D018549:Cryptogenic Organizing Pneumonia / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D000860:Hypoxia; D008297:Male; D008875:Middle Aged; D013902:Radiography, Thoracic; D012680:Sensitivity and Specificity; D015431:Weight Loss
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic