title: [Activities of the fragments of semenogelin I: an update].
abstract: Semenogelin I (Sg I) and the fragments of peptides hydrolyzed from Sg I by prostate-specific antigen have multiple biological activities. There exists a controversy over the inhibitory effect of the key fragment on sperm motility. This article focuses on the sperm-inhibiting and antibacterial activities of the fragments of Sg I-derived peptides and illustrates the supposition concerning the most controversial aspect. A deeper insight into the action mechanisms of Sg I-derived peptides may help improve the methods of sperm screening and provide a new perspective in the management of asthenozoospermia and urinary tract infection.
authors: Department of Urology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650032, China. jyhuchen@126.com
authors: Chen
authors: C
authors: Hu
authors: Hui
authors: H
authors: Zhao
mesh_terms: D000900:Anti-Bacterial Agents; D006801:Humans; D008297:Male; D012661:Semen / Q000187:drug effects; D029607:Seminal Vesicle Secretory Proteins / Q000235:genetics / Q000502:physiology*; D013094:Spermatozoa / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D029607:Seminal Vesicle Secretory Proteins; C424482:seminal vesicle-specific antigen