title: A rare primary tumor of the thyroid gland: report a new case of leiomyosarcoma and literature review.
abstract: Primary leiomyosarcomas of the thyroid gland are extremely rare. we report a case of a 72 year-old women with a painful growing mass of the left neck with skin fistula. The patient underwent a lobectomy. The tumor histology showed spindle-shaped cells arranged in interlacing fascicles that expressed desmine and H-caldesmone, but were negative for cytokeratins and thyroglobulin. Total body CT scan didn't show any other tumor. The patient died two months after surgery. Primary thyroid leiomyosarcoma may be mistaken for other tumors, such as anaplastic or medullary carcinomas. Therefore, the diagnosis is difficult and requires numerous clinical, radiological, and pathological investigations.
  The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1917621950869224.
authors: Departement of pathology, Hassan II University Hospital, Fez 30000, Morocco. bennaniamal@gmail.com
authors: Bennani
authors: B
authors: Amal
authors: Hinde
authors: H
authors: El Fatemi
authors: Ihsane
authors: I
authors: Souaf
authors: Kaouthar
authors: K
authors: Moumna
authors: Amarti
authors: A
authors: Affaf
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D002277:Carcinoma / Q000473:pathology; D018278:Carcinoma, Neuroendocrine; D017577:Cutaneous Fistula / Q000473:pathology; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007890:Leiomyosarcoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D011237:Predictive Value of Tests; D013964:Thyroid Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D013965:Thyroidectomy; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D051598:Whole Body Imaging
chemical_list: D014408:Biomarkers, Tumor