title: Using a state cancer registry to recruit young breast cancer survivors and high-risk relatives: protocol of a randomized trial testing the efficacy of a targeted versus a tailored intervention to increase breast cancer screening.
abstract: BACKGROUND
  The Michigan Prevention Research Center, the University of Michigan Schools of Nursing, Public Health, and Medicine, and the Michigan Department of Community Health propose a multidisciplinary academic-clinical practice three-year project to increase breast cancer screening among young breast cancer survivors and their cancer-free female relatives at greatest risk for breast cancer.
  
  
  METHODS
  The study has three specific aims: 1) Identify and survey 3,000 young breast cancer survivors (diagnosed at 20-45 years old) regarding their breast cancer screening utilization. 2) Identify and survey survivors' high-risk relatives regarding their breast cancer screening utilization. 3) Test two versions (Targeted vs. Enhanced Tailored) of an intervention to increase breast cancer screening among survivors and relatives. Following approval by human subjects review boards, 3,000 young breast cancer survivors will be identified through the Michigan Cancer Registry and mailed an invitation letter and a baseline survey. The baseline survey will obtain information on the survivors': a) current breast cancer screening status and use of genetic counseling; b) perceived barriers and facilitators to screening; c) family health history. Based on the family history information provided by survivors, we will identify up to two high-risk relatives per survivor. Young breast cancer survivors will be mailed consent forms and baseline surveys to distribute to their selected high-risk relatives. Relatives' baseline survey will obtain information on their: a) current breast cancer screening status and use of genetic counseling; and b) perceived barriers and facilitators to screening. Young breast cancer survivors and high-risk relatives will be randomized as a family unit to receive two versions of an intervention aiming to increase breast cancer screening and use of cancer genetic services. A follow-up survey will be mailed 9 months after the intervention to survivors and high-risk relatives to evaluate the efficacy of each intervention version on: a) use of breast cancer screening and genetic counseling; b) perceived barriers and facilitators to screening; c) self-efficacy in utilizing cancer genetic and screening services; d) family support related to screening; e) knowledge of breast cancer genetics; and f) satisfaction with the intervention.
  
  
  CONCLUSIONS
  The study will enhance efforts of the state of Michigan surrounding cancer prevention, control, and public health genomics.
authors: University of Michigan School of Nursing, 400 N, Ingalls Building, Room 2158, Ann Arbor, MI 48109, USA. mkatapo@umich.edu
authors: Maria C
authors: MC
authors: Katapodi
authors: Laurel L
authors: LL
authors: Northouse
authors: Ann M
authors: AM
authors: Schafenacker
authors: Debra
authors: D
authors: Duquette
authors: Sonia A
authors: SA
authors: Duffy
authors: David L
authors: DL
authors: Ronis
authors: Beth
authors: B
authors: Anderson
authors: Nancy K
authors: NK
authors: Janz
authors: Jennifer
authors: J
authors: McLosky
authors: Kara J
authors: KJ
authors: Milliron
authors: Sofia D
authors: SD
authors: Merajver
authors: Linh M
authors: LM
authors: Duong
authors: Glenn
authors: G
authors: Copeland
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000235:genetics; D005195:Family Relations; D005260:Female; D015438:Health Behavior; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008403:Mass Screening / Q000379:methods* / Q000706:statistics & numerical data; D008824:Michigan; D008875:Middle Aged; D018579:Patient Selection; D011446:Prospective Studies; D012042:Registries; D011795:Surveys and Questionnaires; D017741:Survivors; D055815:Young Adult