title: [Renal replacement therapy in a polytraumatized patient with hemophilia].
abstract: Renal failure is a rare complication of hereditary coagulopathies. However, when it occurs, it rapidly progresses to a stage that requires replacement of renal function. Major problems include the choice of dialysis method, prevention of complications and supplementation of deficient factor. In hemodialysis, it is challenging to prevent system clotting and avoid bleeding. We present a case of polytraumatized male patient with hemophilia A, who developed compartment syndrome with acute renal failure. Continuous venovenous hemodialysis (CWHD) improved his condition and he recovered his kidney function. However, over the next few days he developed severe sepsis with deterioration of renal function. CWHDF (hemodiafiltration) was restarted. Several large hematomas were found in the abdominal cavity and in the inguinal region, one of them inducing compartment syndrome with leg necrosis. The patient died from cardiorespiratory arrest.
authors: Zagreb University Hospital Center, Department of Anesthesiology and Intensive Care, Zagreb, Croatia. sanja.sakan@hotmail.com
authors: Sanja
authors: S
authors: Sakan
authors: Daniela
authors: D
authors: Bandić
authors: Mladen
authors: M
authors: Perić
authors: Petar
authors: P
authors: Kes
authors: Nikolina
authors: N
authors: Basić-Jukić
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D000328:Adult; D017809:Fatal Outcome; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D008297:Male; D009104:Multiple Trauma / Q000150:complications*; D017582:Renal Replacement Therapy