title: Thermoresponsive diblock copolymer with tunable soluble-insoluble and soluble-insoluble-soluble transitions.
abstract: The thermoresponsive transition behavior of a diblock copolymer consisting of poly(ethylene glycol) methyl ether (mPEG) and poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) in aqueous solutions has been investigated. With a specific composition, the copolymer showed a unique tunable phase transition from no response in acidic media to a soluble-insoluble (S-I) transition in neutral media and an S-I-S transition in basic media either in the presence of salt or for salt-free solutions. The S-I-S transition can be tuned over a wide temperature range even to an S-I type transition just by adding salts. In addition, phase transitions can occur in both pure water and saline solution under practical conditions (30-80 °C), which makes them suitable for a broad range of applications.
authors: Key Laboratory for Advanced Materials and Department of Chemistry, East China University of Science and Technology, Shanghai 200237, PR China.
authors: Xia
authors: X
authors: Han
authors: Xuxia
authors: X
authors: Zhang
authors: Quanyi
authors: Q
authors: Yin
authors: Jun
authors: J
authors: Hu
authors: Honglai
authors: H
authors: Liu
authors: Ying
authors: Y
authors: Hu
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D008689:Methacrylates / Q000737:chemistry*; D009757:Nylons / Q000737:chemistry*; D044367:Phase Transition; D011092:Polyethylene Glycols / Q000737:chemistry*; D012995:Solubility; D013696:Temperature; D013816:Thermodynamics
chemical_list: D001672:Biocompatible Materials; D008689:Methacrylates; D009757:Nylons; C407037:poly(2-(dimethylamino)ethyl methacrylate); D011092:Polyethylene Glycols