title: Photoimmunosuppression: a brief overview.
abstract: Exposure to ultraviolet radiation can lead to suppression of many adaptive immune responses, both to antigens encountered within a short period of the irradiation (primary) and to antigens previously encountered (memory). The pathways involved are complex and not completely elucidated. This brief review summarizes the information available currently regarding the multiple steps involved, with the aim of providing a general overview of the main aspects of photoimmunosuppression and its clinical consequences.
authors: Dermatological Sciences, Institute of Inflammation and Repair, University of Manchester, Manchester, UK. neil.gibbs@manchester.ac.uk
authors: Neil K
authors: NK
authors: Gibbs
authors: Mary
authors: M
authors: Norval
mesh_terms: D056704:Adaptive Immunity / Q000528:radiation effects; D000818:Animals; D006801:Humans; D007108:Immune Tolerance / Q000528:radiation effects*; D007111:Immunity, Cellular / Q000528:radiation effects; D007113:Immunity, Innate / Q000528:radiation effects; D012867:Skin / Q000276:immunology; D014466:Ultraviolet Rays / Q000009:adverse effects*