title: Clinical Role of Hybrid Imaging.
abstract: Recent technological advances have fueled the growth in hybrid radionuclide and CT imaging of the heart. Noninvasive imaging studies are reliable means to diagnose coronary artery disease (CAD), stratify risk, and guide clinical management. Myocardial perfusion scintigraphy is a robust, widely available noninvasive modality for the evaluation of ischemia from known or suspected CAD. Cardiac CT (coronary artery calcium score and coronary CT angiography) has emerged as a clinically robust noninvasive anatomic imaging test, capable of rapidly diagnosing or excluding obstructive CAD. Both anatomic and functional modalities have strengths and weaknesses, and can complement each other by offering integrated structural and physiologic information. As we discuss below, in selected patients, hybrid imaging may facilitate more accurate diagnosis, risk stratification, and management in a "one-stop shop" setting.
authors: Noninvasive Cardiovascular Imaging Program, Departments of Medicine (Cardiology) and Radiology, and the Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
authors: Edward M
authors: EM
authors: Hsiao
authors: Bilal
authors: B
authors: Ali
authors: Sharmila
authors: S
authors: Dorbala
keywords: CT coronary angiography; Coronary calcium score; Hybrid imaging; Myocardial perfusion scintigraphy/imaging; PET; SPECT