title: DNA methylation dynamics in health and disease.
abstract: DNA methylation is an epigenetic mark that is erased in the early embryo and then re-established at the time of implantation. In this Review, dynamics of DNA methylation during normal development in vivo are discussed, starting from fertilization through embryogenesis and postnatal growth, as well as abnormal methylation changes that occur in cancer.
authors: Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, Hebrew University Medical School, Jerusalem, Israel. yehudit.bergman@huji.ac.il
authors: Yehudit
authors: Y
authors: Bergman
authors: Howard
authors: H
authors: Cedar
mesh_terms: D018899:CpG Islands; D019175:DNA Methylation; D010064:Embryo Implantation; D047108:Embryonic Development / Q000235:genetics; D044127:Epigenesis, Genetic; D018507:Gene Expression Regulation, Developmental; D006801:Humans; D009369:Neoplasms / Q000235:genetics*