title: Exercise capacity and quality of life in patients with schizophrenia.
abstract: The aim of this study was to resolve the relationship between physical capacity (PC) and quality of life (Qol) in schizophrenic patients and healthy controls. 31 patients (PG: 18 male, 13 female) and a control group (CG) of 50 healthy subjects (15 male, 35 female) were involved. PC was assessed as peak oxygen uptake [VO2peak, (ml (min kgKG)(-1))] and power output expressed as watts per kilogram (W kg(-1)). Qol was assessed using the SF-36 questionnaire. Patients with schizophrenia showed reduced VO2peak (male: PG 29 ± 5 vs. CG 44 ± 10; female: PG 21 ± 4 vs. CG 30 ± 8) and power output (male: PG 2.04 ± 0.47 vs. CG 3.43 ± 0.70; female PG 1.40 ± 0.28 vs. CG 2.43 ± 0.52). Scales of the SF-36 questionnaire were lower in the PG. While in the CG correlations were found between PC and several subscales of Qol, this was not the case in the PG. The restricted PC seen in the PG showed no relation to their subjectively assessed worsened Qol, which would indicate that schizophrenic patients evaluate limitations arising from this differently than healthy control subjects.
authors: Institute of Sports Medicine, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany, Kerling.arno@mh-hannover.de.
authors: Arno
authors: A
authors: Kerling
authors: Uwe
authors: U
authors: Tegtbur
authors: Marc
authors: M
authors: Ziegenbein
authors: Lena
authors: L
authors: Grams
authors: Dirk Robert
authors: DR
authors: Heinze
authors: Marcel
authors: M
authors: Sieberer
mesh_terms: D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D016022:Case-Control Studies; D005080:Exercise Test / Q000706:statistics & numerical data; D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D054624:Health Status Disparities; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D019344:Lactic Acid / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011788:Quality of Life; D012559:Schizophrenia / Q000378:metabolism / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D019344:Lactic Acid