title: Mixed sugar-core-phosphate chelation of D-fructose 1,6-bisphosphate with the Re(V)O(tmen) metal fragment.
abstract: Sugar phosphates provide metal-binding sites both at their sugar core and at their phosphate group(s). Mixed sugar-core-phosphate chelation has been considered as a typical bonding mode within the physiological pH range for the central metabolite D-fructose 1,6-bisphosphate. The Re(V)O(tmen) metal fragment was used to enrich this coordination type. The formation of the [ReO(tmen)(Fruf2,3H-21,6P2H2-κ(3)O(2,3,P1))](-) monoanion was determined by NMR spectroscopy and mass spectrometry. The model compound rac-glycerol 1-phosphate yielded similar results in terms of NMR spectroscopy. Crystal-structure analyses of [ReO(tmen)(rac-Glyc2,3H-21PH-κ(3)O(2,3,P))]·2H2O and [ReO(phen)(rac-Glyc2,3H-21PH-κ(3)O(2,3,P))]·MeOH confirmed the coordination pattern.
authors: Department Chemie der Ludwig-Maximilians-Universität, Butenandtstr. 5-13, 81377 Munich, Germany.
authors: Martin
authors: M
authors: Steinborn
authors: Mihael
authors: M
authors: Suhanji
authors: Peter
authors: P
authors: Klüfers
mesh_terms: D002614:Chelating Agents / Q000737:chemistry*; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry; D018360:Crystallography, X-Ray; D005635:Fructosediphosphates / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D012211:Rhenium / Q000737:chemistry*; D013403:Sugar Phosphates / Q000737:chemistry*
chemical_list: D002614:Chelating Agents; D056831:Coordination Complexes; D005635:Fructosediphosphates; D013403:Sugar Phosphates; C015428:perrhenate; D012211:Rhenium; C029063:fructose-1,6-diphosphate