title: Facilitating comparative effectiveness research in cancer genomics: evaluating stakeholder perceptions of the engagement process.
abstract: OBJECTIVE
  The Center for Comparative Effectiveness Research in Cancer Genomics completed a 2-year stakeholder-guided process for the prioritization of genomic tests for comparative effectiveness research studies. We sought to evaluate the effectiveness of engagement procedures in achieving project goals and to identify opportunities for future improvements.
  
  
  METHODS
  The evaluation included an online questionnaire, one-on-one telephone interviews and facilitated discussion. Responses to the online questionnaire were tabulated for descriptive purposes, while transcripts from key informant interviews were analyzed using a directed content analysis approach.
  
  
  RESULTS
  A total of 11 out of 13 stakeholders completed both the online questionnaire and interview process, while nine participated in the facilitated discussion. Eighty-nine percent of questionnaire items received overall ratings of agree or strongly agree; 11% of responses were rated as neutral with the exception of a single rating of disagreement with an item regarding the clarity of how stakeholder input was incorporated into project decisions. Recommendations for future improvement included developing standard recruitment practices, role descriptions and processes for improved communication with clinical and comparative effectiveness research investigators.
  
  
  CONCLUSIONS
  Evaluation of the stakeholder engagement process provided constructive feedback for future improvements and should be routinely conducted to ensure maximal effectiveness of stakeholder involvement.
authors: Patricia A
authors: PA
authors: Deverka
authors: Danielle C
authors: DC
authors: Lavallee
authors: Priyanka J
authors: PJ
authors: Desai
authors: Joanne
authors: J
authors: Armstrong
authors: Mark
authors: M
authors: Gorman
authors: Leah
authors: L
authors: Hole-Curry
authors: James
authors: J
authors: O'Leary
authors: B W
authors: BW
authors: Ruffner
authors: John
authors: J
authors: Watkins
authors: David L
authors: DL
authors: Veenstra
authors: Laurence H
authors: LH
authors: Baker
authors: Joseph M
authors: JM
authors: Unger
authors: Scott D
authors: SD
authors: Ramsey
mesh_terms: D057186:Comparative Effectiveness Research / Q000592:standards*; D003299:Cooperative Behavior; D023281:Genomics; D006801:Humans; D007398:Interpersonal Relations; D009369:Neoplasms / Q000235:genetics*; D012107:Research Design / Q000592:standards*; D012108:Research Personnel; D011795:Surveys and Questionnaires; D014481:United States