title: [Influence of combined lacto-vegetarian diet and selective beta-blocking agents on clinical and metabolic indices in patients with coronary heart disease].
abstract: Clinical, hemodynamic and metabolic parameters were investigated for 42 patients with coronary heart disease, after myocardial infarct, recieved selective beta-adrenoblockers. Patients were divided in two groups. The first group (24 patients) were given methoprolol (50 mg/daily) and antiatherogenic lacto vegetarian diet, the second (18 patients)--methoprolol (50 mg/daily) and standard mixed antiatherogenic diet. After the treatment, positive changes clinical and gemodynamic parameters were observed in both groups of patients. Among the clinical symptoms, a more pronounced decrease in blood pressure in the patients on vegetarian diet and a more significant increase in their exercise tolerance. The level of total cholesterol on the serum of blood decreased by 16%, low-density lipoproteins cholesterol decreased by 18%, the atherogenic coefficient (KA) decreased by 31%, only in vegetarian group. High-density lipoprotein cholesterol increased in vegetarian group, by 14% and decreased in control group. Balanced antiatherogenic lacto vegetarian diet in patients with coronary heart disease prevents the hyperlipedemic effect caused by the selective beta-adrenoblockers and it is an agent for preventing its negative effect on lipid metabolism.
authors: A A
authors: AA
authors: Ieromuzo
authors: I L
authors: IL
authors: Medkova
authors: Iu V
authors: IuV
authors: Nemytin
authors: A N
authors: AN
authors: Ivanov
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003327:Coronary Disease / Q000097:blood / Q000178:diet therapy* / Q000188:drug therapy* / Q000503:physiopathology; D014676:Diet, Vegetarian; D006294:Health Resorts; D006334:Heart Function Tests; D006801:Humans; D008055:Lipids / Q000097:blood; D008875:Middle Aged; D009753:Nutritive Value; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D008055:Lipids