title: Vulnerable plaque: from bench to bedside; local pacification versus systemic therapy.
abstract: Critical coronary stenoses accounts for a small proportion of acute coronary syndromes and sudden death. The majority are caused by coronary thromboses that arise from a nonangiographically obstructive atheroma. Recent developments in noninvasive imaging of so-called vulnerable plaques created opportunities to direct treatment to prevent morbidity and mortality associated with these high-risk lesions. This review covers therapy employed in the past, present, and potentially in the future as the natural history of plaque assessment unfolds.
authors: Cardiology Unit, Medical Faculty, UiTM Sg Buloh, Selangor, Malaysia ; Division of Cardiology, Cork University Hospital, Cork, Ireland.
authors: Sazzli
authors: S
authors: Kasim
authors: Darragh
authors: D
authors: Moran
authors: Eugene
authors: E
authors: McFadden
keywords: Atherosclerosis; intervention; pathogenesis; treatment; vulnerable plaque