title: Orbital follicular hyperplasia in common variable immune deficiency syndrome.
abstract: Common variable immune deficiency (CVID) is characterized by reduced serum immune globulins and impaired or absent antibody responses. Patients become more susceptible to infections and to lymphoproliferation and granulomatous inflammation. Ophthalmic manifestations of CVID are rare. The authors describe a case of orbital follicular hyperplasia in a 15-year-old girl with CVID syndrome causing proptosis and exposure keratopathy.
authors: *Department of Ophthalmology, Massachusetts Eye and Ear Infirmary; †Department of Ophthalmology, Harvard Medical School; ‡Department of Ophthalmology, Boston Children's Hospital; §Department of Pathology, Boston Children's Hospital; ‖Department of Pathology, Harvard Medical School; ¶Department of Allergy/Immunology, Boston Children's Hospital; and #Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, U.S.A.
authors: Meenakashi
authors: M
authors: Gupta
authors: Ankoor S
authors: AS
authors: Shah
authors: Jo-Anne
authors: JA
authors: Vergilio
authors: Janet
authors: J
authors: Chou
authors: Alexandra
authors: A
authors: Elliott
mesh_terms: D000293:Adolescent; D005094:Exophthalmos / Q000209:etiology; D005145:Face / Q000002:abnormalities*; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000209:etiology; D007153:Immunologic Deficiency Syndromes / Q000150:complications*; D009915:Orbit / Q000473:pathology*; D009916:Orbital Diseases / Q000209:etiology*; D000081207:Primary Immunodeficiency Diseases