title: Perioperative and early oncological outcomes after robot-assisted radical prostatectomy (RARP) in morbidly obese patients: a propensity score-matched study.
abstract: OBJECTIVE
  To evaluate the perioperative and pathological outcomes associated with robot-assisted radical prostatectomy (RARP) in morbidly obese men.
  
  
  METHODS
  Between January 2008 and March 2012, 3041 patients underwent RARP at our institution by a single surgeon (V.P.). In all, 44 patients were considered morbidly obese with a body mass index (BMI) of ≥40 kg/m(2) . A propensity score-matched analysis was conducted using multivariable analysis to identify comparable groups of patients with a BMI of ≥40 and <40 kg/m(2) . Perioperative, pathological outcomes and complications were compared between the two matched groups.
  
  
  RESULTS
  There was no significant difference in operative time. However, the mean estimated blood loss was higher in morbidly obese patients, at a mean (sd) of 113 (41) vs 130 (27) mL (P = 0.049). Anastomosis was more difficult in morbidly obese patients (P = 0.001). There were no significant differences in laterality, ease of nerve sparing, or transfusion rate between the groups. There were no intraoperative complications in either group. Postoperative pathological outcomes were similar between the groups. Differences in positive surgical margins and ease of nerve sparing approached statistical significance (P = 0.097, P = 0.075 respectively). Postoperative complication rates, pain scores, length of stay and indwelling catheter duration were similar in the groups.
  
  
  CONCLUSIONS
  RARP in morbidly obese patients is technically demanding. However, it can be accomplished with acceptable morbidity and resource use. In the hands of an experienced surgeon, it is a safe procedure and offers beneficial clinical outcomes.
authors: Global Robotics Institute, Florida Hospital Celebration Health, Celebration, FL, USA.
authors: Haidar
authors: H
authors: Abdul-Muhsin
authors: Camilo
authors: C
authors: Giedelman
authors: Srinivas
authors: S
authors: Samavedi
authors: Oscar
authors: O
authors: Schatloff
authors: Rafael
authors: R
authors: Coelho
authors: Bernardo
authors: B
authors: Rocco
authors: Kenneth
authors: K
authors: Palmer
authors: George
authors: G
authors: Ebra
authors: Vipul
authors: V
authors: Patel
mesh_terms: D001803:Blood Transfusion / Q000706:statistics & numerical data; D015992:Body Mass Index; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D061646:Operative Time; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D057216:Propensity Score; D011468:Prostatectomy / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D011471:Prostatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018570:Risk Assessment; D012371:Robotics; D025321:Surgery, Computer-Assisted / Q000009:adverse effects / Q000401:mortality; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology
keywords: RARP; morbid obesity