title: Room-temperature photoinduced direct C-H-arylation via base-promoted homolytic aromatic substitution.
abstract: Conceptually different approach toward biaryl syntheses by photoinduced direct C-H arylation of benzene and thiophene in the presence of t-BuOK is reported. The reaction proceeds through photo- and base-promoted homolytic aromatic substitution. The o-, m- and p- substituted ArI, as well as the electron-donating and electron-withdrawing nature of the substituents were found be good to excellent substrates. Heteroaryl, ArBr, ArCl and double C-H arylation were successfully achieved.
authors: INFIQC, Departamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, X5000HUA Córdoba, Argentina.
authors: María E
authors: ME
authors: Budén
authors: Javier F
authors: JF
authors: Guastavino
authors: Roberto A
authors: RA
authors: Rossi
mesh_terms: D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D015394:Molecular Structure; D055668:Photochemical Processes; D013696:Temperature; D013876:Thiophenes / Q000737:chemistry*
chemical_list: D001555:Benzene Derivatives; D013876:Thiophenes