title: [Functional MRI by general radiologists in prediction of side-specific extracapsular extension after radical prostatectomy: what value in daily practice?].
abstract: OBJECTIVE
  To evaluate the performance of functional MRI (FMRI) performed by general radiologists (GR) in detection of side-specific extracapsular extension (SSECE) prostate cancer (PCa).
  
  
  METHODS
  We retrospectively analyzed 79 patients who underwent FMRI with pelvic phased array coil before radical prostatectomy (RP) performed at University Hospital (UH) of Nîmes. Twelve GR (including three from UH) interpreted the images during their daily practice. FMRI results were dichotomized as positive or negative and confronted to pathological reports for SSECE and side-specific seminal vesicle invasion (SSSVI), with calculation of diagnostic values. The influence of interval between biopsy and FMRI, diffusion-weighted sequence (DWS) and intensity of FMRI, on the diagnostic performance were assessed by Fisher's exact test.
  
  
  RESULTS
  A SSECE and a SSSVI were observed at FMRI and pathology respectively on 14 (8.8%) and 38 (24.1%) prostate lobes, and on six (3.8%) and seven (4.4%) prostate lobes. The sensitivity, specificity, positive and negative predictive values of FMRI for SSECE were respectively 24%, 96%, 64% and 80%; and for SSSVI were 14%, 97%, 17% and 96% respectively. The time between biopsy and FMRI, intensity of FMRI and DWS, did not influence the sensitivity and specificity of fMRI at Fisher test.
  
  
  CONCLUSIONS
  This study found that preoperative prostate FMRI performed by GR has good specificity but poor sensitivity in predicting SSECE on pathological reports.
authors: Service d'urologie, CHU de Nîmes, place du Professeur-Debré, 30029 Nîmes, France. maxkadoch@hotmail.fr
authors: A D
authors: AD
authors: Foahom Kamwa
authors: P
authors: P
authors: Costa
authors: L
authors: L
authors: Soustelle
authors: L
authors: L
authors: Wagner
authors: C
authors: C
authors: Duflos
authors: P
authors: P
authors: Gres
authors: J-L
authors: JL
authors: Faillie
authors: K
authors: K
authors: Ben Naoum
authors: M
authors: M
authors: Boukaram
authors: S
authors: S
authors: Droupy
mesh_terms: D000368:Aged; D001706:Biopsy / Q000379:methods; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery*; D011871:Radiology; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012669:Seminal Vesicles / Q000473:pathology; D012680:Sensitivity and Specificity; D016896:Treatment Outcome; D000078329:Workforce