title: [Optic nerve head drusen in children--visual function and OCT outcomes].
abstract: OBJECTIVE
  To evaluate the effect of optic nerve head drusen on retinal nerve fiber layer (RNFL) thickness in children, with the use of optical coherence tomography (OCT).
  
  
  METHODS
  21 patients (mean age 13.9 years) with optic nerve head drusen were studied prospectively. For statistic comparison a group of 15 control subjects (mean age 14.1 years) participated. Ophthalmologic examination, automated visual field testing and optical coherence tomography were performed in each patient. For statistical analysis we used Shapiro-Wilk and U Mann-Whitney tests.
  
  
  RESULTS
  In the OCT measurements the nasal RNFL was significantly thinner as compared to the reference group. Neither statistically significant thinning of global RNFL between groups nor relation between subjects age and RNFL thickness was found.
  
  
  CONCLUSIONS
  Optic nerve head drusen can lead to visual function defects, therefore early and correct diagnosis is mandatory. Optical coherence tomography is a usefull diagnostic tool used to determine the cause of disc elevation, which is especially important in childhood, when drusen can cause disc to appear papilledema-like. Overall OCT appears to be a non-invasive, sensitive and early-indicating method of RNFL thinning.
authors: Klinika Okulistyki Dzieciecej z Ośrodkiem Leczenia Zeza Uniwersytetu Medycznego w Białymstoku. beti.c@interia.pl
authors: Beata
authors: B
authors: Chrzanowska
authors: Michał
authors: M
authors: Szumiński
authors: Alina
authors: A
authors: Bakunowicz-Łazarczyk
mesh_terms: D000293:Adolescent; D005260:Female; D006801:Humans; D008297:Male; D009412:Nerve Fibers / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology*; D015594:Optic Disk Drusen / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D011044:Poland; D011446:Prospective Studies; D012016:Reference Values; D012160:Retina / Q000473:pathology; D041623:Tomography, Optical Coherence / Q000379:methods*; D014786:Vision Disorders / Q000209:etiology*; D014792:Visual Acuity; D014794:Visual Fields; D055815:Young Adult