title: Effects of huangqi and bear bile on recurrent parotitis in children: a new clinical approach.
abstract: OBJECTIVE
  To evaluate the pharmacological effects of traditional Chinese medicine, bear bile capsule and Huangqi granule, on recurrent parotitis in children.
  
  
  METHODS
  In this prospective, controlled, and randomized study, a total of 151 young children were divided into three groups: Group A included massaging the children's parotid region and melting vitamin C in their mouth daily; Group B included swallowing bear bile capsule and Huangqi granule daily; and Group C included massages and vitamin C as prescribed in Group A, and traditional Chinese medicine as prescribed in Group B. Children were treated individually for one month and then a follow-up study was conducted for 1 to 3.5 years. Analysis of variance (ANOVA) and Ridit analysis were employed for statistical analysis.
  
  
  RESULTS
  The recurrence rate decreased in every group, but was significantly more in Groups B and C when compared to Group A. The recurrences significantly decreased (P<0.01) in Group B and their recovery rate was as high as 63%, significantly better than those of the other groups (P<0.01).
  
  
  CONCLUSIONS
  Huangqi and bear bile could be a novel clinical approach for treating recurrent parotitis in children.
authors: Department of Stomatology, Children's Hospital, School of Medicine, Zhejiang University, Hangzhou, China. ruanwh1@sohu.com
authors: Wen-hua
authors: WH
authors: Ruan
authors: Mei-li
authors: ML
authors: Huang
authors: Xiao-lei
authors: XL
authors: He
authors: Feng
authors: F
authors: Zhang
authors: Hai-biao
authors: HB
authors: Tao
mesh_terms: D000293:Adolescent; D000818:Animals; D027883:Astragalus Plant; D027885:Astragalus propinquus; D001646:Bile / Q000737:chemistry*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010309:Parotitis / Q000188:drug therapy*; D055502:Secondary Prevention; D016896:Treatment Outcome; D001503:Ursidae / Q000378:metabolism*
chemical_list: D004365:Drugs, Chinese Herbal; C027492:Huang Qi