title: In search of the missing ligands for TetR family regulators.
abstract: The TetR family of microbial transcription factors directly control the expression of a diverse range of genes in bacteria by sensing specific ligands. In this issue of Chemistry & and Biology, Cuthbertson and colleagues used phylogenomics to guide the identification of TetR-like protein cognate ligands and revealed a novel inducible antibiotic resistance mechanism.
authors: Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK. c.corre@warwick.ac.uk
authors: Christophe
authors: C
authors: Corre