title: Septic shock after seasonal influenza vaccination in an HIV-infected patient during treatment with etanercept for rheumatoid arthritis: a case report.
abstract: Anti-tumor necrosis factor alpha (anti-TNF-α) is used in the treatment of rheumatic diseases not responsive to first-line regimens. Data on the safety of anti-TNF-α in HIV-infected patients are scarce and conflicting. We describe a case of septic shock and multiorgan failure that occurred after etanercept initiation and influenza vaccination in an HIV-infected woman with rheumatoid arthritis.
authors: National Institute for Infectious Diseases L. Spallanzani, Rome, Italy. dr.pasqualedenardo@gmail.com
authors: Pasquale
authors: P
authors: De Nardo
authors: Rita
authors: R
authors: Bellagamba
authors: Angela
authors: A
authors: Corpolongo
authors: Elisa
authors: E
authors: Gentilotti
authors: Fabrizio
authors: F
authors: Taglietti
authors: Silvia
authors: S
authors: Rosati
authors: Mauro
authors: M
authors: Galeazzi
authors: Gian Domenico
authors: GD
authors: Sebastiani
authors: Isabella
authors: I
authors: Quinti
authors: Emanuele
authors: E
authors: Nicastri
mesh_terms: D023241:Antiretroviral Therapy, Highly Active; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000188:drug therapy*; D000068800:Etanercept; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007074:Immunoglobulin G / Q000009:adverse effects* / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use; D012772:Shock, Septic / Q000209:etiology*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors; D014611:Vaccination
chemical_list: D018501:Antirheumatic Agents; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents; D007252:Influenza Vaccines; D018124:Receptors, Tumor Necrosis Factor; D014409:Tumor Necrosis Factor-alpha; D000068800:Etanercept