title: Synthesis of 2-aryl-3-fluoro-5-silylthiophenes via a cascade reactive sequence.
abstract: 2-Aryl-3-fluoro-5-silylthiophenes were readily prepared only in two steps from 2-bromo-3,3,3-trifluoropropene in good yields. These transformations include the first successful S(N)2'-type reaction of 2-bromo-3,3,3-trifluoropropene and benzylthiols and [2,3]sigmatropic rearrangement of 2-bromo-3,3-difluoroallyl benzyl sulfide.
authors: Department of Chemistry and Applied Chemistry, Saga University, Honjyo-machi 1, Saga 840-8502, Japan.
authors: Kensuke
authors: K
authors: Hirotaki
authors: Takeshi
authors: T
authors: Hanamoto
mesh_terms: D002384:Catalysis; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012821:Silanes / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013438:Sulfhydryl Compounds / Q000737:chemistry; D013440:Sulfides / Q000737:chemistry; D013876:Thiophenes / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D006842:Hydrocarbons, Brominated; D006845:Hydrocarbons, Fluorinated; D012821:Silanes; D013438:Sulfhydryl Compounds; D013440:Sulfides; D013876:Thiophenes