title: Late onset CNS immune reconstitution inflammatory syndrome in an immunocompetent patient.
abstract: Immune reconstitution inflammatory syndrome (IRIS) refers to the presence of paradoxical clinical deterioration attributable to immune system recovery during highly active antiretroviral therapy (HAART). We present an immunocompetent patient with multifocal leukoencephalopathy on HAART, with central nervous system (CNS) IRIS pathology of unknown infectious etiology. CNS IRIS pathology should be suspected in patients on longstanding HAART without immune reconstitution, presenting with unexplained leukoencephalopathy.
authors: Department of Neurology, Stritch School of Medicine, Loyola University Chicago Maywood, IL, USA.
authors: Alejandro
authors: A
authors: Hornik
authors: Federico
authors: F
authors: Rodriguez-Porcel
authors: Shawn
authors: S
authors: Wallery
authors: Murray
authors: M
authors: Flaster
authors: John M
authors: JM
authors: Lee
authors: José
authors: J
authors: Biller
keywords: AIDS; HIV; IRIS; multifocal leukoencephalopathy; seizures