title: An unusual case of E coli meningitis in a patient with Marfan's syndrome.
abstract: Spontaneous non-traumatic Escherichia coli meningitis is very rare in adults. We report a case of a 48-year-old woman with Marfan's syndrome with E coli meningitis. Apparently, the relation between an increased risk of meningitis and Marfan's syndrome is not well known. This patient was discharged on intravenous antibiotic therapy after a diagnosis of E coli meningitis without looking for the cause by imaging studies previously. Her blood cultures were negative ruling out haematogenous spread. Our work-up revealed extensive dural ectasia with intrasacral meningoceles extending into the pelvis possibly acting as a portal of entry for the bacteria into the brain from the gastrointestinal tract.
authors: Scott & White Infectious Diseases Division, Texas A & M School of Medicine, Temple, TX, USA. drraghesh.vk@gmail.com
authors: Raghesh Varot
authors: RV
authors: Kangath
authors: John
authors: J
authors: Midturi
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D004927:Escherichia coli Infections / Q000175:diagnosis* / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008382:Marfan Syndrome / Q000150:complications*; D008581:Meningitis / Q000175:diagnosis* / Q000188:drug therapy* / Q000382:microbiology*; D008875:Middle Aged
chemical_list: D000900:Anti-Bacterial Agents