title: Diagnostic accuracy of computed tomography findings for patients undergoing salvage total laryngectomy.
abstract: CONCLUSIONS
  Computed tomography (CT) imaging has clear limitations for the diagnosis of cartilage invasion or tumor spread in recurrent laryngeal cancer. Alternative methods of pretreatment assessment are needed for recurrent laryngeal cancer.
  
  
  OBJECTIVE
  The diagnosis and staging of recurrent laryngeal cancer, previously treated by radiation therapy (RT), remains challenging. Practically, surgeons need to depend on imaging to predict which patients will have a chance for conservation salvage laryngectomy. The purpose of the present study was to determine the accuracy of preoperative CT performed for recurrent laryngeal carcinoma evaluation following RT.
  
  
  METHODS
  This retrospective review identified 32 patients who underwent salvage total laryngectomy after RT from 1998 to 2010. For our radiologic classification of the thyroid cartilage, we analyzed the conditions as normal, sclerosis, invasion, penetration, and extralaryngeal spread and categorized the state of the arytenoids and cricoid into three possible conditions: normal, sclerosis, and destruction. Radiographic findings were correlated with pathology findings.
  
  
  RESULTS
  Sensitivity and specificity for the detection of the thyroid cartilage infiltration were 57% and 94%, 50% and 89% for the cricoid cartilage, and 33% and 76% for arytenoid cartilage, respectively. The accuracy of recurrent tumor classification was 59.4%. Three carcinomas were over-staged and 10 were under-staged.
authors: Department of Otolaryngology, Ulsan University Hospital, Ulsan, Republic of Korea.
authors: Myung Woul
authors: MW
authors: Han
authors: Sun-A
authors: SA
authors: Kim
authors: Kyung-Ja
authors: KJ
authors: Cho
authors: Jeong Hyun
authors: JH
authors: Lee
authors: Hyun Kyung
authors: HK
authors: Lim
authors: Jong-Lyel
authors: JL
authors: Roh
authors: Seung-Ho
authors: SH
authors: Choi
authors: Sang Yoon
authors: SY
authors: Kim
authors: Soon Yuhl
authors: SY
authors: Nam
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy / Q000601:surgery; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging* / Q000601:surgery; D011300:Preoperative Care; D016879:Salvage Therapy; D014057:Tomography, X-Ray Computed