title: Emergence of Clostridium difficile infection in tuberculosis patients due to a highly rifampicin-resistant PCR ribotype 046 clone in Poland.
abstract: Clostridium difficile infection (CDI) is a major cause of nosocomial diarrhea. CDI is known to develop after antibiotic administration, but anti-tuberculosis agents have rarely been implicated. We documented an outbreak caused by a highly rifampicin-resistant C. difficile strain of polymerase chain reaction (PCR) ribotype 046 in patients with active tuberculosis.
authors: Department of Medical Microbiology, Medical University of Warsaw, 5 Chałubiński Street, 02-004, Warsaw, Poland.
authors: P
authors: P
authors: Obuch-Woszczatyński
authors: G
authors: G
authors: Dubiel
authors: C
authors: C
authors: Harmanus
authors: E
authors: E
authors: Kuijper
authors: U
authors: U
authors: Duda
authors: D
authors: D
authors: Wultańska
authors: A
authors: A
authors: van Belkum
authors: H
authors: H
authors: Pituch
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000904:Antibiotics, Antitubercular / Q000494:pharmacology; D016360:Clostridioides difficile / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D003015:Clostridium Infections / Q000382:microbiology*; D015331:Cohort Studies; D003428:Cross Infection / Q000382:microbiology; D004196:Disease Outbreaks; D024881:Drug Resistance, Bacterial; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011044:Poland; D012293:Rifampin / Q000494:pharmacology*; D014376:Tuberculosis / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D000904:Antibiotics, Antitubercular; D012293:Rifampin