title: [Prevalence of osteoporosis in patients with severe peripheral artery disease].
abstract: BACKGROUND
  Recent studies highlighted a significant association between bone mineral density and atherosclerosis. Cardiovascular disease is the main cause of death in Western countries, while the prevalence of osteoporosis reached 9% in Hungary.
  
  
  OBJECTIVE
  The aim of this study was to investigate the prevalence of osteoporosis among patients with peripheral vascular disease.
  
  
  METHODS
  In a cross-sectional study bone mineral density using dual-energy X-ray absorptiometry in 172 patients with lower limb ischemia was investigated. According to previous medical history and blood tests, risk factors of atherosclerosis were also assessed and serum markers of bone turnover and other factors that could influence osteoporosis were evaluated.
  
  
  RESULTS
  Prior to bone mineral density screening, osteoporosis was known in 9% of patients. Based on osteodensitometric evaluation, 37% of the patients were diagnosed as having osteopenia and 31% as having osteoporosis. According to risk factors, different patient groups were created. Significantly more female than male patients had osteoporosis, while smoking, age and body mass index failed to affect the prevalence of osteoporosis.
  
  
  CONCLUSIONS
  These results suggest that patients with severe atherosclerosis need to be regularly screened and, if necessary, treated for osteoporosis.
authors: Semmelweis Egyetem, Általános Orvostudományi Kar, Szív- és Érsebészeti Klinika, Budapest. fehervarimatyi@gmail.com
authors: Mátyás
authors: M
authors: Fehérvári
authors: Miklós
authors: M
authors: Krepuska
authors: Csaba
authors: C
authors: Csobay-Novák
authors: Péter
authors: P
authors: Lakatos
authors: Zoltán
authors: Z
authors: Oláh
authors: György
authors: G
authors: Acsády
authors: Zoltán
authors: Z
authors: Szeberin
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D015415:Biomarkers / Q000097:blood; D015992:Body Mass Index; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D015663:Osteoporosis, Postmenopausal / Q000453:epidemiology; D058729:Peripheral Arterial Disease / Q000150:complications* / Q000175:diagnosis; D015995:Prevalence; D012307:Risk Factors; D012720:Severity of Illness Index; D017678:Sex Distribution; D012907:Smoking / Q000009:adverse effects
chemical_list: D015415:Biomarkers