title: General synthesis of sugar-derived azepane nitrones: precursors of azepane iminosugars.
abstract: A general and efficient method has been developed for the synthesis of sugar-derived azepane nitrones starting from aldohexoses, with an intramolecular condensation of aldehyde and hydroxylamine as the key step. Through this strategy, each aldohexose produced a pair of azepane nitrones, which are precursors of various azepane iminosugars.
authors: Beijing National Laboratory of Molecular Science, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
authors: Wen-Bo
authors: WB
authors: Zhao
authors: Shinpei
authors: S
authors: Nakagawa
authors: Atsushi
authors: A
authors: Kato
authors: Isao
authors: I
authors: Adachi
authors: Yue-Mei
authors: YM
authors: Jia
authors: Xiang-Guo
authors: XG
authors: Hu
authors: George W J
authors: GW
authors: Fleet
authors: Francis X
authors: FX
authors: Wilson
authors: Graeme
authors: G
authors: Horne
authors: Akihide
authors: A
authors: Yoshihara
authors: Ken
authors: K
authors: Izumori
authors: Chu-Yi
authors: CY
authors: Yu
mesh_terms: D002241:Carbohydrates / Q000737:chemistry*; D015394:Molecular Structure; D009589:Nitrogen Oxides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D002241:Carbohydrates; D009589:Nitrogen Oxides