title: Hemophagocytic syndrome in an acute human immunodeficiency virus infection.
abstract: Hemophagocytic syndrome (HPS) is an unrecognized complication occurring in the acute stage of human immunodeficiency virus (HIV) infection that is seldom reported in the literature. We herein present a case of HPS that occurred during the seroconversion stage of HIV infection. In this case, pancytopenia and liver dysfunction related to HPS recovered after the initiation of antiretroviral therapy (ART). This report indicates the importance of early recognition of HPS and suggests that prompt initiation of ART has the potential to control HPS in the acute stage of HIV infection.
authors: Department of Infectious Diseases and Applied Immunology, Research Hospital of The Institute of Medical Science, The University of Tokyo, Japan. e-adachi@ims.u-tokyo.ac.jp
authors: Eisuke
authors: E
authors: Adachi
authors: Tomohiko
authors: T
authors: Koibuchi
authors: Kentaro
authors: K
authors: Imai
authors: Tadashi
authors: T
authors: Kikuchi
authors: Shoichi
authors: S
authors: Shimizu
authors: Michiko
authors: M
authors: Koga
authors: Hitomi
authors: H
authors: Nakamura
authors: Aikichi
authors: A
authors: Iwamoto
authors: Takeshi
authors: T
authors: Fujii
mesh_terms: D000208:Acute Disease; D023241:Antiretroviral Therapy, Highly Active; D003937:Diagnosis, Differential; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000150:complications* / Q000175:diagnosis* / Q000821:virology; D008297:Male; D008875:Middle Aged