title: Closure of patent ductus arteriosus in children, small infants, and premature babies with Amplatzer duct occluder II additional sizes: multicenter study.
abstract: OBJECTIVE
  To evaluate safety and efficacy of closure of patent ductus arteriosus (PDA) with Amplatzer duct occluder II Additional Sizes (ADO II AS) and to report early and midterm results of the device in children and very young symptomatic infants.
  
  
  METHODS
  Retrospective analysis of angiographic data of 60 children from four pediatric cardiology centers.
  
  
  RESULTS
  The median patient age and weight were 6.5 (0.5-168) months and 6.8 (1.19-57) kg, respectively. In the study, 26 children had a body weight of ≤ 6 kg. Of these 26 children, 9 had a body weight of ≤ 3 kg. The median narrowest diameter of PDA was 2 (1.2-4) mm. Ductal anatomy was Type A in 29, Type B in 2, Type C in 11, Type D in 1, and Type E in 16 patients, and a residual PDA after surgery in 1 patient. Closure with ADO II AS was achieved in 58 (96.6%) of 60 attempted cases. In two infants, the device was not released because of significant residual shunt. ADO II was used in one, and the other was sent to surgery. Complete closure was observed in all ADO II AS deployed children by the next day on echocardiography. Median follow-up was 12 (1-18) months. Neither death nor any major complications occurred.
  
  
  CONCLUSIONS
  Our study shows that closure of medium and small sized PDA by using ADO II AS device is effective and safe in children. The use of the device will expand the field of application of PDA closure in small infants.
authors: Department of Pediatric Cardiology, Ondokuz Mayis University, Samsun, Turkey. metsungur@yahoo.com
authors: Metin
authors: M
authors: Sungur
authors: Cemsit
authors: C
authors: Karakurt
authors: Nazan
authors: N
authors: Ozbarlas
authors: Osman
authors: O
authors: Baspinar
mesh_terms: D001835:Body Weight; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000295:instrumentation*; D002675:Child, Preschool; D017023:Coronary Angiography; D004374:Ductus Arteriosus, Patent / Q000175:diagnosis / Q000628:therapy*; D004452:Echocardiography; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D011474:Prosthesis Design; D012189:Retrospective Studies; D055989:Septal Occluder Device; D013997:Time Factors; D016896:Treatment Outcome; D014421:Turkey
keywords: children; duct occluder; patent ductus arteriosus; pediatric interventions; premature baby