title: Congenital kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon successfully treated with low-dose radiation therapy.
abstract: Kaposiform hemangioendothelioma (KHE) associated with Kasabach-Merritt phenomenon is a life-threatening vasculopathy. The current mainstay treatment for KHEs is corticosteroids and chemotherapy, but these medications do not work for all patients and carry significant side effects. We report a neonate with a large congenital KHE who responded extremely well to low-dose radiation therapy.
authors: Division of Neonatology, Yale University, New Haven, Connecticut; Division of Neonatology, Maria Fareri Children's Hospital, New York Medical College, Westchester, New York.
authors: Yogangi
authors: Y
authors: Malhotra
authors: Catherine S
authors: CS
authors: Yang
authors: Joseph
authors: J
authors: McNamara
authors: Richard J
authors: RJ
authors: Antaya
mesh_terms: D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D006390:Hemangioendothelioma / Q000151:congenital / Q000532:radiotherapy*; D006801:Humans; D007231:Infant, Newborn; D059885:Kasabach-Merritt Syndrome / Q000151:congenital / Q000532:radiotherapy*; D008297:Male; D011296:Prenatal Diagnosis; D011879:Radiotherapy Dosage; D012514:Sarcoma, Kaposi / Q000151:congenital / Q000532:radiotherapy*