title: Selective ruthenium-catalyzed transfer hydrogenations of nitriles to amines with 2-butanol.
abstract: Transfer your hydrogen: Fast and general transfer hydrogenation of nitriles to form primary amines is possible with a homogeneous Ru/1,4-bis(diphenylphosphino)butane (DPPB) catalyst (see scheme). The use of 2-butanol as the hydrogen-transfer reagent is essential for the selective reduction of aromatic, heteroaromatic, and aliphatic nitriles with this system.
authors: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock, Germany.
authors: Svenja
authors: S
authors: Werkmeister
authors: Christoph
authors: C
authors: Bornschein
authors: Kathrin
authors: K
authors: Junge
authors: Matthias
authors: M
authors: Beller
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D000440:Butanols / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006859:Hydrogen; D006865:Hydrogenation; D009570:Nitriles / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D000588:Amines; D000440:Butanols; D009570:Nitriles; C043958:2-butanol; D012428:Ruthenium; D006859:Hydrogen