title: [Progress in clinical bone assessment using CT].
abstract: Clinical computed tomography (CT) provides the information of bone structure and mineral density in vivo . Based on three-dimensional bone structure, voluntary two-dimensional sections are available, as well as trabecular and cortical data separately. However, the trabecular structure, which size is smaller than the spatial resolution, cannot be measured precisely. A recently system, high-resolution peripheral quantitative CT (HR-pQCT) , can visualize and quantify the trabecular and cortical microstructure in vivo . Because of low radiation dose and high reproducibility, HR-pQCT system is expected to be a useful tool to assess the pathophysiological changes or the efficacy of anti-osteoporotic agents on bone.
authors: Medical Work-Life-Balance Center, Nagasaki University Hospital, Japan.
authors: Masako
authors: M
authors: Ito
mesh_terms: D015519:Bone Density; D001847:Bone Diseases / Q000175:diagnosis*; D001842:Bone and Bones / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D015203:Reproducibility of Results; D014057:Tomography, X-Ray Computed / Q000295:instrumentation*