title: A telephone-supported cardiovascular lifestyle programme (CLIP) for lipid reduction and weight loss in general practice patients: a randomised controlled pilot trial.
abstract: OBJECTIVE
  To evaluate a primary prevention care model using telephone support delivered through an existing health call centre to general practitioner-referred patients at risk of developing CVD, using objective measures of CVD risk reduction and weight loss.
  
  
  METHODS
  Participants were randomised into two groups: (i) those receiving a telephone-supported comprehensive lifestyle intervention programme (CLIP: written structured diet and exercise advice, plus seven telephone sessions with the Heart Foundation Health Information Service); and (ii) those receiving usual care from their general practitioner (control: written general lifestyle advice). Fasting plasma lipids, blood pressure, weight, waist circumference and height were assessed on general practice premises by a practice nurse at Weeks 0 and 12.
  
  
  METHODS
  Two general practices in Adelaide, South Australia.
  
  
  METHODS
  Forty-nine men and women aged 48·0 (sd 5·88) years identified by their general practitioner as being at future risk of CVD (BMI = 33·13 (sd 5·39) kg/m2; LDL cholesterol (LDL-C) = 2·66 (sd 0·92) mmol/l).
  
  
  RESULTS
  CLIP participants demonstrated significantly greater reductions in LDL-C (estimated mean (EM) = 1·98 (se 0·17) mmol/l) and total cholesterol (EM = 3·61 (se 0·21) mmol/l) at Week 12 when compared with the control group (EM = 3·23 (se 0·18) mmol/l and EM = 4·77 (se 0·22) mmol/l, respectively). There were no significant treatment effects for systolic blood pressure (F(1,45) = 0·28, P = 0·60), diastolic blood pressure (F(1,43) = 0·52, P = 0·47), weight (F(1,42) = 3·63, P = 0·063) or waist circumference (F(1,43) = 0·32, P = 0·577).
  
  
  CONCLUSIONS
  In general practice patients, delivering CLIP through an existing telephone health service is effective in achieving reductions in LDL-C and total cholesterol. While CLIP may have potential for wider implementation to support primary prevention of CVD, longer-term cost-effectiveness data are warranted.
authors: 1 Discipline of General Practice, School of Population Health and Clinical Practice, The University of Adelaide, Adelaide, Australia.
authors: Keren Louise
authors: KL
authors: Stuart
authors: 2 Commonwealth Scientific and Industrial Research Organisation (CSIRO), Animal, Food and Health Sciences, PO Box 10041, Adelaide, SA 5000, Australia.
authors: Belinda
authors: B
authors: Wyld
authors: 2 Commonwealth Scientific and Industrial Research Organisation (CSIRO), Animal, Food and Health Sciences, PO Box 10041, Adelaide, SA 5000, Australia.
authors: Kathryn
authors: K
authors: Bastiaans
authors: 1 Discipline of General Practice, School of Population Health and Clinical Practice, The University of Adelaide, Adelaide, Australia.
authors: Nigel
authors: N
authors: Stocks
authors: 2 Commonwealth Scientific and Industrial Research Organisation (CSIRO), Animal, Food and Health Sciences, PO Box 10041, Adelaide, SA 5000, Australia.
authors: Grant
authors: G
authors: Brinkworth
authors: 2 Commonwealth Scientific and Industrial Research Organisation (CSIRO), Animal, Food and Health Sciences, PO Box 10041, Adelaide, SA 5000, Australia.
authors: Phil
authors: P
authors: Mohr
authors: 2 Commonwealth Scientific and Industrial Research Organisation (CSIRO), Animal, Food and Health Sciences, PO Box 10041, Adelaide, SA 5000, Australia.
authors: Manny
authors: M
authors: Noakes
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000097:blood / Q000517:prevention & control*; D008078:Cholesterol, LDL / Q000097:blood; D003376:Counseling / Q000379:methods*; D005247:Feeding Behavior / Q000523:psychology; D005260:Female; D058006:General Practice / Q000379:methods; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000628:therapy; D008019:Life Style; D008297:Male; D008875:Middle Aged; D010353:Patient Education as Topic; D010865:Pilot Projects; D012017:Referral and Consultation; D040242:Risk Reduction Behavior; D012944:Social Support; D013021:South Australia; D017216:Telemedicine / Q000379:methods*; D013689:Telephone; D016896:Treatment Outcome; D015431:Weight Loss
chemical_list: D008078:Cholesterol, LDL