title: Branch retinal vein occlusion associated with tamoxifen use.
abstract: Tamoxifen is a selective estrogen receptor modulator widely used in the treatment of hormone-responsive breast cancer. Tamoxifen-induced ocular complications are very rare. A post-menopausal woman with carcinoma of the left breast had presented with sudden loss of vision. The patient had been on tamoxifen therapy 20 mg daily for the last three years. Fundus examination showed left branch retinal vein occlusion. Fluorescein angiography and optical coherence tomography confirmed the diagnosis. Tamoxifen therapy was discontinued. Although branch retinal vein occlusion is rare, careful evaluation of patients on tamoxifen therapy with visual symptoms is required.
authors: Duzce University Medical Faculty, Department of Ophthalmology, Duzce, Turkey. dribrahimonder@yahoo.com
authors: Halil İbrahim
authors: Hİ
authors: Onder
authors: Ali Cagri
authors: AC
authors: Kilic
authors: Seyit Ali
authors: SA
authors: Kose
authors: Ahmet
authors: A
authors: Karatas
authors: Ertugrul
authors: E
authors: Kaya
authors: Murat
authors: M
authors: Kaya
authors: Murat
authors: M
authors: Tunc
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008408:Mastectomy; D008875:Middle Aged; D012170:Retinal Vein Occlusion / Q000139:chemically induced* / Q000175:diagnosis; D020845:Selective Estrogen Receptor Modulators / Q000009:adverse effects*; D013629:Tamoxifen / Q000009:adverse effects*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity
chemical_list: D018931:Antineoplastic Agents, Hormonal; D020845:Selective Estrogen Receptor Modulators; D013629:Tamoxifen