title: Optimal composition of dialysis fluid for on-line hemodiafiltration in central dialysis fluid delivery system.
abstract: In this paper, we propose 'the preferred composition of dialysis fluid for on-line hemodiafiltration (HDF) in central dialysis fluid delivery system, (CDDS)': sodium concentration 138-140 mEq/l; potassium concentration 2.0 mEq/l; calcium concentration 2.5-3.5 mEq/l; glucose concentration 1.0-1.5 g/l; buffer: bicarbonate (acetate free is preferred). Concentrations of electrolytes in dialysis fluid (= substitution fluid) are applied to the compositions of launched dialysis fluid in Japan. From the viewpoint of biocompatibility and correction of metabolic acidosis, acetate-free bicarbonate buffer is thought to be important. This proposal of the preferred composition of dialysis fluid for on-line HDF in CDDS is based on a few reports. Further investigations and research to reveal the optimal composition of dialysis fluid for on-line HDF are expected in the future.
authors: Department of Nephrology, Oita University Hospital, Oita, Japan. tomo@oita-u.ac.jp
authors: Tadashi
authors: T
authors: Tomo
mesh_terms: D000138:Acidosis / Q000209:etiology; D001639:Bicarbonates; D002021:Buffers; D004573:Electrolytes; D005947:Glucose; D017583:Hemodiafiltration / Q000009:adverse effects / Q000379:methods; D015312:Hemodialysis Solutions / Q000737:chemistry*; D006801:Humans; D009752:Nutritional Status
chemical_list: D001639:Bicarbonates; D002021:Buffers; D004573:Electrolytes; D015312:Hemodialysis Solutions; D005947:Glucose