title: [Clinical nuclear medicine in bone metastases].
abstract: (99m)Tc-hydroxymethylene diphosphonate is not directly to Calcium of the bone matrix, but is binding to hydroxyapatite within the bone matrix. Strontium-89 is a member of family II A of the periodic table, same as Calcium, and is incorporated into bone matrix directly. It is very important that the the regions of the pain from bone metastases are present in the site of the abnormal uptake by bone metastases.
authors: Department of Nuclear Medicine, Osaka City University, Japan.
authors: Joji
authors: J
authors: Kawabe
authors: Shigeaki
authors: S
authors: Higashiyama
authors: Susumu
authors: S
authors: Shiomi
mesh_terms: D001857:Bone Matrix / Q000378:metabolism; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000556:secondary / Q000628:therapy*; D006801:Humans; D009683:Nuclear Medicine / Q000379:methods; D019275:Radiopharmaceuticals / Q000627:therapeutic use*; D013326:Strontium Radioisotopes / Q000627:therapeutic use; D013669:Technetium Tc 99m Medronate / Q000627:therapeutic use
chemical_list: D019275:Radiopharmaceuticals; D013326:Strontium Radioisotopes; D013669:Technetium Tc 99m Medronate