title: C-4 modified sialosides enhance binding to Siglec-2 (CD22): towards potent Siglec inhibitors for immunoglycotherapy.
authors: Centre for Biomolecular Interactions Bremen, Department of Biology and Chemistry, University of Bremen, 28334 Bremen, Germany. skelm@uni-bremen.de
authors: Sørge
authors: S
authors: Kelm
authors: Paul
authors: P
authors: Madge
authors: Tasneem
authors: T
authors: Islam
authors: Ryan
authors: R
authors: Bennett
authors: Hendrik
authors: H
authors: Koliwer-Brandl
authors: Mario
authors: M
authors: Waespy
authors: Mark
authors: M
authors: von Itzstein
authors: Thomas
authors: T
authors: Haselhorst
mesh_terms: D015703:Antigens, CD / Q000378:metabolism; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000628:therapy; D006801:Humans; D007167:Immunotherapy; D016393:Lymphoma, B-Cell / Q000628:therapy; D009682:Magnetic Resonance Spectroscopy; D018992:Myelin-Associated Glycoprotein / Q000037:antagonists & inhibitors / Q000378:metabolism; D011485:Protein Binding; D051918:Sialic Acid Binding Ig-like Lectin 2 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D063265:Sialic Acid Binding Immunoglobulin-like Lectins / Q000037:antagonists & inhibitors / Q000378:metabolism; D012794:Sialic Acids / Q000737:chemistry* / Q000378:metabolism
chemical_list: D015703:Antigens, CD; D000970:Antineoplastic Agents; D018992:Myelin-Associated Glycoprotein; C412227:SIGLEC9 protein, human; D051918:Sialic Acid Binding Ig-like Lectin 2; D063265:Sialic Acid Binding Immunoglobulin-like Lectins; D012794:Sialic Acids