title: Two new tri-nor-eudesmanolides from Inula racemosa.
abstract: Two new tri-nor-eudesmane-type sesquiterpenoids were isolated from the roots of Inula racemosa, and their structures were elucidated as 8-oxo-tri-nor-eudesm-6-en-5α-ol (1) and tri-nor-eudesm-5-en-7β,8β-diol (2). The cytotoxic activity of compound 1 against five human cancer cell lines had been tested, but exhibited no cytotoxic activity.
authors: State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors: Ting
authors: T
authors: Zhang
authors: Ting
authors: T
authors: Gong
authors: Ruo-Yun
authors: RY
authors: Chen
authors: De-Quan
authors: DQ
authors: Yu
mesh_terms: D004354:Drug Screening Assays, Antitumor; D006801:Humans; D038143:Inula / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D045787:Sesquiterpenes, Eudesmane / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018609:Tibet
chemical_list: C582407:8-oxo-tri-nor-eudesm-6-en-5alpha-ol; D045787:Sesquiterpenes, Eudesmane; C582406:tri-nor-eudesm-5-en-7beta,8beta-diol