title: Structure and function of mycobacterium glycopeptidolipids from comparative genomics perspective.
abstract: Glycopeptidolipids (GPLs) attached to the outer surface of the greasy cell envelope, are a class of important glycolipids synthesized by several non-tuberculosis mycobacteria. The deletion or structure change of GPLs confers several phenotypical changes including colony morphology, hydrophobicity, aggregation, sliding motility, and biofilm formation. In addition, GPLs, particular serovar specific GPLs, are important immunomodulators. This review aims to summarize the advance on the structure, function and biosynthesis of mycobacterium GPLs.
authors: Institute of Modern Biopharmaceuticals, State Key Laboratory Breeding Base of Eco-Environment and Bio-Resource of the Three Gorges Area, School of Life Sciences, Southwest University, Beibei, Chongqing 400715, China.
authors: Lei
authors: L
authors: Pang
authors: Xuelian
authors: X
authors: Tian
authors: Weihua
authors: W
authors: Pan
authors: Jianping
authors: J
authors: Xie
mesh_terms: D006017:Glycolipids / Q000096:biosynthesis* / Q000737:chemistry*; D009161:Mycobacterium / Q000737:chemistry* / Q000276:immunology / Q000378:metabolism*; D013329:Structure-Activity Relationship
chemical_list: D006017:Glycolipids