title: In vivo imaging using polymeric nanoparticles stained with near-infrared chemiluminescent and fluorescent squaraine catenane endoperoxide.
abstract: Polystyrene nanoparticles stained with squaraine catenane endoperoxide exhibit remarkably high chemiluminescence and enable optical imaging of biodistribution in living mice. Whole-body chemiluminescence imaging was much more effective than fluorescence at identifying lung accumulation of the nanoparticles.
authors: Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
authors: Jung-Jae
authors: JJ
authors: Lee
authors: Alexander G
authors: AG
authors: White
authors: Douglas R
authors: DR
authors: Rice
authors: Bradley D
authors: BD
authors: Smith
mesh_terms: D000818:Animals; D000873:Anthracenes / Q000737:chemistry*; D003503:Cyclobutanes / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry / Q000378:metabolism*; D008099:Liver / Q000000981:diagnostic imaging; D008168:Lung / Q000000981:diagnostic imaging; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry*; D010545:Peroxides / Q000737:chemistry / Q000378:metabolism*; D010636:Phenols / Q000737:chemistry*; D011137:Polystyrenes / Q000737:chemistry; D011859:Radiography; D019265:Spectroscopy, Near-Infrared; D014018:Tissue Distribution
chemical_list: D000873:Anthracenes; D003503:Cyclobutanes; D005456:Fluorescent Dyes; D010545:Peroxides; D010636:Phenols; D011137:Polystyrenes; C467767:catenane; C480596:squaraine