title: The first reported case of rabbit hemorrhagic disease in Canada.
abstract: In March 2011, rabbit hemorrhagic disease (RHD) was suspected in a 1-year-old male neutered lop-eared rabbit that had acute onset liver failure. Gross pathology, histopathology, immunohistochemistry, partial nucleic acid sequencing and phylogenetic analysis of the major capsid protein (VP60) and animal inoculation studies all supported this diagnosis making it the first confirmed case of RHD in Canada.
  
  
  
  In March 2011, rabbit hemorrhagic disease (RHD) was suspected in a 1-year-old male neutered lop-eared rabbit that had acute onset liver failure. Gross pathology, histopathology, immunohistochemistry, partial nucleic acid sequencing and phylogenetic analysis of the major capsid protein (VP60) and animal inoculation studies all supported this diagnosis making it the first confirmed case of RHD in Canada.
authors: Canadian Food Inspection Agency, National Centres for Animal Disease, Winnipeg, Manitoba R3E 3M4.
authors: Carissa
authors: C
authors: Embury-Hyatt
authors: Rosemary
authors: R
authors: Postey
authors: Tamiko
authors: T
authors: Hisanaga
authors: Lynn
authors: L
authors: Burton
authors: Kathleen
authors: K
authors: Hooper-McGrevy
authors: Leanne
authors: L
authors: McIntyre
authors: Kevin
authors: K
authors: Millar
authors: John
authors: J
authors: Pasick
mesh_terms: D000818:Animals; D001483:Base Sequence; D017250:Caliciviridae Infections / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D002170:Canada / Q000453:epidemiology; D036022:Capsid Proteins / Q000235:genetics / Q000378:metabolism; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D017929:Hemorrhagic Disease Virus, Rabbit / Q000235:genetics / Q000302:isolation & purification*; D008297:Male; D011817:Rabbits
chemical_list: D036022:Capsid Proteins