title: Brachial artery aneurysm accompanying a homozygous methylenetetrahydrofolate reductase mutation.
abstract: Elevated plasma homocysteine (Hcy) is one of the suggested risk factors for endothelial dysfunction. There is evidence of association between raised plasma Hcy and an increased risk of developing peripheral arterial disease. A causal relationship, however, has not been established. In this report, a 37-year old male patient with the complaints of intermittent hand pain is presented. Brachial artery aneurysm accompanying a homozygous methylenetetrahydrofolate reductase mutation was detected.
authors: Department of Cardiac and Vascular Surgery, Gulhane Military Medical Academy, Etlik, Ankara, Turkey.
authors: Adem
authors: A
authors: Guler
authors: Murat
authors: M
authors: Tavlasoglu
authors: Zekeriya
authors: Z
authors: Arslan
authors: Fahri Gurkan
authors: FG
authors: Yesil
mesh_terms: D000328:Adult; D000783:Aneurysm / Q000175:diagnosis / Q000209:etiology*; D015415:Biomarkers / Q000097:blood; D001916:Brachial Artery; D004252:DNA Mutational Analysis; D020022:Genetic Predisposition to Disease; D006710:Homocysteine / Q000097:blood; D006720:Homozygote; D006801:Humans; D020138:Hyperhomocysteinemia / Q000097:blood / Q000150:complications / Q000201:enzymology / Q000235:genetics*; D008297:Male; D042965:Methylenetetrahydrofolate Reductase (NADPH2) / Q000235:genetics*; D009154:Mutation; D010641:Phenotype; D012501:Saphenous Vein / Q000637:transplantation; D016896:Treatment Outcome; D058017:Vascular Grafting
chemical_list: D015415:Biomarkers; D006710:Homocysteine; C573423:MTHFR protein, human; D042965:Methylenetetrahydrofolate Reductase (NADPH2)
keywords: Brachial artery aneurysm