title: A CRISPR way to engineer the human genome.
abstract: RNA-guided genome engineering based on the type II prokaryotic CRISPR/Cas system provides an efficient and versatile method for targeted manipulation of mammalian genomes.
authors: Sivaprakash
authors: S
authors: Ramalingam
authors: Narayana
authors: N
authors: Annaluru
authors: Srinivasan
authors: S
authors: Chandrasegaran
mesh_terms: D000818:Animals; D064113:CRISPR-Cas Systems; D005818:Genetic Engineering / Q000379:methods*; D015894:Genome, Human; D006801:Humans