title: Effects of aging and mild cognitive impairment on electrophysiological correlates of performance monitoring.
abstract: Performance monitoring tasks are suitable for investigating aging-related decline in executive functions. However, little is known about performance monitoring in premature pathological aging and mild cognitive impairment (MCI). This study recorded the error-related negativity (ERN) and the correct-related negativity (CRN) as indices of performance monitoring and compared these responses in older adults with MCI to the ones of younger and older adult controls. No differences in either ERN or CRN were found between younger and older adult controls. Compared to both control groups, we observed a more negatively pronounced CRN in MCI subjects. Only in this group did the amplitude of the CRN not differ from the one of the ERN. In general, larger differences between both components (i.e., ERN > CRN) were associated with better performances in cognitive tests requiring inhibition and executive control. These results indicate that electrophysiological correlates of performance monitoring (ERN and CRN) are differentially affected by aging and MCI.
authors: Department of Psychology, University of Konstanz, Konstanz, Germany. thurm@psychologie.tu-dresden.de
authors: Franka
authors: F
authors: Thurm
authors: Daria
authors: D
authors: Antonenko
authors: Winfried
authors: W
authors: Schlee
authors: Stephan
authors: S
authors: Kolassa
authors: Thomas
authors: T
authors: Elbert
authors: Iris-Tatjana
authors: IT
authors: Kolassa
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001288:Attention / Q000502:physiology*; D001921:Brain / Q000503:physiopathology; D060825:Cognitive Dysfunction / Q000175:diagnosis* / Q000503:physiopathology*; D003265:Contingent Negative Variation / Q000502:physiology*; D004569:Electroencephalography; D005071:Evoked Potentials / Q000502:physiology*; D056344:Executive Function / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011930:Reaction Time / Q000502:physiology; D012016:Reference Values; D012815:Signal Processing, Computer-Assisted