title: Rare case of blastemal predominant adult Wilms' tumor with skeletal metastasis case report and brief review of literature.
abstract: Wilms' tumor (nephroblastoma) is extremely rare in adults, skeletal metastasis being still rarer. The clinical course of adult Wilms' tumor is very aggressive. The present case is a rare blastemal predominant adult Wilms' tumor presenting with skeletal metastasis. We report a case of 19-year-old female presented with severe low backache and colicky left loin pain of 3 months and progressive weakness of 15 days duration. Magnetic resonance image (MRI) of lumbosacral spine was reported as spinal metastasis with right renal mass. The patient underwent right radical nephrectomy and the tumor was histopathologically confirmed as adult Wilms' tumor. In case of adult Wilms' tumor, distant metastasis may be the first presentation and this possibility should be considered when an adult patient presents with flank pain and a renal mass.
authors: Department of Pathology, Sri Venketeswar Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.
authors: Rashmi
authors: R
authors: Patnayak
authors: D V S
authors: DV
authors: Rambabu
authors: Amitabh
authors: A
authors: Jena
authors: Bodagala
authors: B
authors: Vijaylaxmi
authors: B V
authors: BV
authors: Phaneendra
authors: M Kumaraswamy
authors: MK
authors: Reddy
keywords: Adult Wilms’ tumor; renal tumor; skeletal metastasis