title: Seed-development programs: a systems biology-based comparison between dicots and monocots.
abstract: Seeds develop differently in dicots and monocots, especially with respect to the major storage organs. High-resolution transcriptome data have provided the first insights into the molecular networks and pathway interactions that function during the development of individual seed compartments. Here, we review mainly recent data obtained by systems biology-based approaches, which have allowed researchers to construct and model complex metabolic networks and fluxes and identify key limiting steps in seed development. Comparative coexpression network analyses define evolutionarily conservative (FUS3/ABI3/LEC1) and divergent (LEC2) networks in dicots and monocots. Finally, we discuss the determination of seed size--an important yield-related characteristic--as mediated by a number of processes (maternal and epigenetic factors, fine-tuned regulation of cell death in distinct seed compartments, and endosperm growth) and underlying genes defined through mutant analyses. Altogether, systems approaches can make important contributions toward a more complete and holistic knowledge of seed biology and thus support strategies for knowledge-based molecular breeding.
authors: Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), D-06466 Gatersleben, Germany. srinivas@ipk-gatersleben.de.
authors: Nese
authors: N
authors: Sreenivasulu
authors: Ulrich
authors: U
authors: Wobus
mesh_terms: D019684:Magnoliopsida / Q000145:classification / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism*; D053858:Metabolic Networks and Pathways; D060066:Protein Interaction Maps; D012639:Seeds / Q000254:growth & development* / Q000378:metabolism*; D049490:Systems Biology / Q000379:methods*; D059467:Transcriptome