title: Rosuvastatin was Effective in Acute Heart Failure and Slow Coronary Flow: A Hypothesis-generating Case Report.
abstract: Slow coronary flow phenomenon (SCFP) is characterized by angiographically normal coronary arteries with delayed run-off of contrast medium across the vasculature. Its etiology and clinical significance are still not completely known; however, acute congestive heart failure (CHF) is rare in this context. A 71 year-old woman with SCFP presented with acute CHF complicated by ventricular tachycardia. Treated with rosuvastatin (20 mg/day for 6 days) and inotropic drug infusion she had a complete recovery of left ventricular function and normalization of serum levels of the high-sensitivity C-reactive protein (hs-CRP), which were increased (3.6 mg/L) during the acute phase. This case illustrates that the anti-inflammatory properties of rosuvastatin may deserve specific clinical tests not only during the chronic phase but also in the acute phase of CHF patients.
authors: Interventional Cardiology Unit, Santa Maria University Hospital, Terni, Italy.
authors: Alessio
authors: A
authors: Arrivi
authors: Gaetano
authors: G
authors: Tanzilli
authors: Paolo Emilio
authors: PE
authors: Puddu
authors: Luca
authors: L
authors: Iannucci
authors: Enrico
authors: E
authors: Mangieri
keywords: Rosuvastatin; acute heart failure; slow coronary flow.