title: Fusarium graminearum and Its Interactions with Cereal Heads: Studies in the Proteomics Era.
abstract: The ascomycete fungal pathogen Fusarium graminearum (teleomorph stage: Gibberella zeae) is the causal agent of Fusarium head blight in wheat and barley. This disease leads to significant losses of crop yield, and especially quality through the contamination by diverse fungal mycotoxins, which constitute a significant threat to the health of humans and animals. In recent years, high-throughput proteomics, aiming at identifying a broad spectrum of proteins with a potential role in the pathogenicity and host resistance, has become a very useful tool in plant-fungus interaction research. In this review, we describe the progress in proteomics applications toward a better understanding of F. graminearum pathogenesis, virulence, and host defense mechanisms. The contribution of proteomics to the development of crop protection strategies against this pathogen is also discussed briefly.
authors: Enzyme and Protein Chemistry, Department of Systems Biology, Technical University of Denmark Lyngby, Denmark ; Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen Frederiksberg C, Denmark.
authors: Fen
authors: F
authors: Yang
authors: Susanne
authors: S
authors: Jacobsen
authors: Hans J L
authors: HJ
authors: Jørgensen
authors: David B
authors: DB
authors: Collinge
authors: Birte
authors: B
authors: Svensson
authors: Christine
authors: C
authors: Finnie
keywords: Fusarium graminearum; Fusarium head blight; pathogenicity; plant defense response; proteomics