title: Sulfonylation of quinoline N-oxides with aryl sulfonyl chlorides via copper-catalyzed C-H bonds activation.
abstract: An efficient and concise one-pot protocol to synthesize sulfonylated quinoline N-oxides via copper-catalyzed C-H bond activation has been developed. Commercially available and less expensive aryl sulfonyl chlorides were used as the sulfonylation reagents. Various 2-aryl sulfonyl quinolines were obtained in up to 91% yields in chemo- and regioselective manners.
authors: Department of Chemistry, Henan Key Laboratory of Chemical Biology and Organic Chemistry, Zhengzhou University, Zhengzhou, 450052, P. R. China.
authors: Zhiyong
authors: Z
authors: Wu
authors: Hongyu
authors: H
authors: Song
authors: Xiuling
authors: X
authors: Cui
authors: Chao
authors: C
authors: Pi
authors: Weiwei
authors: W
authors: Du
authors: Yangjie
authors: Y
authors: Wu
mesh_terms: D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003300:Copper / Q000737:chemistry*; D006843:Hydrocarbons, Chlorinated / Q000737:chemistry*; D015394:Molecular Structure; D011804:Quinolines / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism; D013441:Sulfinic Acids / Q000737:chemistry; D013450:Sulfones / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D006843:Hydrocarbons, Chlorinated; D011804:Quinolines; D013441:Sulfinic Acids; D013450:Sulfones; C044255:sulfonyl chloride; D003300:Copper