title: The risk of placenta accreta following primary elective caesarean delivery: a case-control study.
abstract: OBJECTIVE
  To evaluate the risk of placenta praevia accreta following primary (first) elective or primary emergency caesarean section in a pregnancy complicated by placenta praevia.
  
  
  METHODS
  Retrospective matched case-control study, employing variable matching.
  
  
  METHODS
  Tertiary referral centre between 1993 and 2008.
  
  
  METHODS
  Sixty-five cases and 102 controls were used for the analysis from a total of 82 667 births during the study period.
  
  
  METHODS
  Relevant data were abstracted from clinical records. Matching of cases with controls was based on co-existing placenta praevia, number of previous caesarean sections, and age, with one or two controls per case. Results are presented as odds ratios (ORs) with 95% confidence intervals (95% CIs).
  
  
  METHODS
  Placenta accreta in a pregnancy complicated by placenta praevia following a primary elective or emergency caesarean section, and morbidity associated with pregnancies complicated by placenta accreta.
  
  
  RESULTS
  Significantly more cases than controls had an elective caesarean section for their primary caesarean delivery (46.2 versus 18.6%; P < 0.001). There were no differences between groups for previous pregnancy loss, uterine surgery, and vaginal delivery, before or after the primary caesarean section. Compared with primary emergency caesarean section, primary elective caesarean section significantly increased the risk of placenta accreta in a subsequent pregnancy in the presence of placenta praevia (OR 3.00; 95% CI 1.47-6.12; P = 0.025).
  
  
  CONCLUSIONS
  Our results suggest that women with a primary elective caesarean section without labour are more likely, compared with those undergoing primary emergency caesarean section with labour, to develop an accreta in a subsequent pregnancy with placenta praevia.
authors: School of Women's and Infants' Health, The University of Western Australia, Crawley, WA, Australia.
authors: M
authors: M
authors: Kamara
authors: J J
authors: JJ
authors: Henderson
authors: D A
authors: DA
authors: Doherty
authors: J E
authors: JE
authors: Dickinson
authors: C E
authors: CE
authors: Pennell
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002585:Cesarean Section; D017558:Elective Surgical Procedures; D004638:Emergency Treatment; D005260:Female; D006801:Humans; D016015:Logistic Models; D016555:Matched-Pair Analysis; D016017:Odds Ratio; D010921:Placenta Accreta / Q000209:etiology*; D010923:Placenta Previa; D011183:Postoperative Complications; D011247:Pregnancy; D012189:Retrospective Studies; D012306:Risk