title: Monte Carlo lookup table-based inverse model for extracting optical properties from tissue-simulating phantoms using diffuse reflectance spectroscopy.
abstract: We present a Monte Carlo lookup table (MCLUT)-based inverse model for extracting optical properties from tissue-simulating phantoms. This model is valid for close source-detector separation and highly absorbing tissues. The MCLUT is based entirely on Monte Carlo simulation, which was implemented using a graphics processing unit. We used tissue-simulating phantoms to determine the accuracy of the MCLUT inverse model. Our results show strong agreement between extracted and expected optical properties, with errors rate of 1.74% for extracted reduced scattering values, 0.74% for extracted absorption values, and 2.42% for extracted hemoglobin concentration values.
authors: Biomedical Engineering, University of Texas at Austin, 107 W. Dean Keaton, Austin, Texas 78712, USA. hennessy@utexas.edu
authors: Ricky
authors: R
authors: Hennessy
authors: Sam L
authors: SL
authors: Lim
authors: Mia K
authors: MK
authors: Markey
authors: James W
authors: JW
authors: Tunnell
mesh_terms: D000042:Absorption; D003198:Computer Simulation; D006454:Hemoglobins / Q000737:chemistry; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008954:Models, Biological; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D015203:Reproducibility of Results; D013057:Spectrum Analysis / Q000295:instrumentation / Q000379:methods*
chemical_list: D006454:Hemoglobins