title: WaveLight FS200 vs Hansatome LASIK: intraoperative determination of flap characteristics and predictability by hand-held bioptigen spectral domain ophthalmic imaging system.
abstract: OBJECTIVE
  To intraoperatively determine and compare the characteristics and predictability of LASIK flaps made by the WaveLight FS200 femtosecond laser (Alcon Laboratories Inc) and Hansatome (Bausch & Lomb) microkeratome using a hand-held spectral domain ophthalmic imaging system (Bioptigen Inc).
  
  
  METHODS
  Sixty eyes from 30 patients undergoing bilateral LASIK were prospectively evaluated. Patients were divided into two equal groups to undergo flap creation with either 100-microm femtosecond laser flaps (FS flap group) or 120-microm microkeratome flaps (MK flap group). Flap thickness was measured intraoperatively after creation of the flap but prior to lifting using the hand-held probe of the spectral domain imaging system. Geometry of the flap edge and smoothness of the stromal bed after lifting the flap was also evaluated in all cases.
  
  
  RESULTS
  Mean difference between planned and achieved flap thickness in the paracentral region was 2.84 +/- 3.16 mm for the FS flap group and 11.33 +/- 10.27 mm for the MK flap group, whereas in the periphery, it was 5.72 +/- 3.26 mm in the FS flap group and 24.67 +/- 10.35 mm in the MK flap group. The differences between groups were statistically significant (P < 0.001, Kruskal-Wallis test). The edges of the flaps were vertical in the FS flap group and the stromal bed was smoother, whereas in the MK flap group, the edges were more sloping and the stromal bed more irregular.
  
  
  CONCLUSIONS
  The WaveLight FS200 femtosecond laser is able to produce planar flaps with a high degree of predictability between the desired and achieved flap thickness. The ability to study the flap characteristics intraoperatively (when flap edema and stromal bed hydration changes have not yet occurred) with the hand-held probe of the Bioptigen imaging system ensures greater accuracy than measurements done postoperatively using other anterior segment optical coherence tomography prototypes.
authors: Narayana Nethralaya Eye Hospital, Bangalore, India.
authors: Rohit
authors: R
authors: Shetty
authors: Chintan
authors: C
authors: Malhotra
authors: Sharon
authors: S
authors: D'Souza
authors: Kareeshma
authors: K
authors: Wadia
mesh_terms: D000328:Adult; D001251:Astigmatism / Q000601:surgery*; D003319:Corneal Stroma / Q000473:pathology*; D005260:Female; D006801:Humans; D007432:Intraoperative Period; D020731:Keratomileusis, Laser In Situ / Q000295:instrumentation*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D011446:Prospective Studies; D015203:Reproducibility of Results; D013524:Surgical Flaps / Q000473:pathology*; D041623:Tomography, Optical Coherence; D055815:Young Adult