title: Comparison of left ventricular geometry after HeartMate II and HeartWare left ventricular assist device implantation.
abstract: BACKGROUND
  HeartMate II (HM II) and HeartWare (HW) Left Ventricular Assist Devices have been successfully used in end-stage heart failure patients as a bridge to transplantation, recovery, or decision. We set out to compare their effect in off-loading the left ventricle and its geometry.
  
  
  METHODS
  The left ventricular end diastolic (LVEDD) and end systolic (LVESD) diameters were compared between first time HM II (n = 25) and HW implantations (n = 24) before and after the operation at 1, 3, and 6 months. A p value of less than 0.05 was considered as significant.
  
  
  RESULTS
  Post-operative LVEDD and LVESD at 1, 3, and 6 months were significantly reduced in comparison with pre-operative values in both HM II and HW groups. No significant difference was found comparing HM II and HW groups together before and after the operation.
  
  
  CONCLUSIONS
  Our study shows that both HM II and HW can significantly reduce the left ventricular systolic and diastolic dimensions and off-load the left ventricle. The miniaturized nature of HW does not affect its performance and it could be as effective as HM II.
authors: Department of Cardiothoracic Surgery and Transplantation Harefield Hospital, Harefield, London, UK. morteza.tavakkoli@gmail.com
authors: Morteza Tavakkoli
authors: MT
authors: Hosseini
authors: Aron Frederik
authors: AF
authors: Popov
authors: Andre Ruediger
authors: AR
authors: Simon
authors: Mohamed
authors: M
authors: Amrani
authors: Toufan
authors: T
authors: Bahrami
mesh_terms: D000328:Adult; D006348:Cardiac Surgical Procedures / Q000295:instrumentation / Q000379:methods*; D002311:Cardiomyopathy, Dilated / Q000601:surgery; D004452:Echocardiography; D005260:Female; D006333:Heart Failure / Q000517:prevention & control; D006352:Heart Ventricles / Q000033:anatomy & histology* / Q000601:surgery*; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D008875:Middle Aged; D019919:Prosthesis Implantation; D012189:Retrospective Studies