title: Gallium analogue of soluble Prussian blue KGa[Fe(CN)6]·nH2O: synthesis, characterization, and potential biomedical applications.
abstract: The gallium analogue of the soluble Prussian blue with the formula KGa[Fe(CN)6]·nH2O is synthesized and structurally characterized. A simple aqueous synthetic procedure for preparing nanoparticles of this novel coordination polymer is reported. The stability, in vitro ion exchange with ferrous ions, cytotoxicity, and cellular uptake of such nanoparticles coated with poly(vinylpyrrolidone) are investigated for potential applications of delivering Ga(3+) ions into cells or removing iron from cells.
authors: Department of Chemistry and Biochemistry, Kent State University, Kent, Ohio 44240, USA.
authors: Murthi S
authors: MS
authors: Kandanapitiye
authors: Benjamin
authors: B
authors: Valley
authors: Liu D
authors: LD
authors: Yang
authors: Allyson M
authors: AM
authors: Fry
authors: Patrick M
authors: PM
authors: Woodward
authors: Songping D
authors: SD
authors: Huang
mesh_terms: D060326:Chemistry Techniques, Synthetic; D004337:Drug Carriers / Q000138:chemical synthesis* / Q000737:chemistry*; D005292:Ferricyanides / Q000138:chemical synthesis* / Q000737:chemistry*; D005295:Ferrocyanides / Q000138:chemical synthesis* / Q000737:chemistry*; D005708:Gallium / Q000737:chemistry* / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D008958:Models, Molecular; D008968:Molecular Conformation; D012995:Solubility
chemical_list: D004337:Drug Carriers; D005292:Ferricyanides; D005295:Ferrocyanides; C583325:potassium gallium(III) hexacyanoferrate(II); D005708:Gallium; C000170:ferric ferrocyanide