title: Comparison of three commercial one-dose porcine circovirus type 2 (PCV2) vaccines on PCV2 shedding in semen from experimentally infected boars.
abstract: This study compared the effects of 3 different types of commercial PCV2 vaccines on PCV2 virus shedding in the semen from infected boars. Twenty-five non-PCV2 viremic and seronegative boars were randomly divided into five groups: three vaccinated and challenged groups, a non-vaccinated and challenged group, and a negative control group. The number of genomic copies of PCV2 in serum and semen samples was significantly decreased in vaccinated and challenged boars compared to non-vaccinated and challenged boars from 14 to 70 days post-inoculation (dpi). The number of PCV2 genomic copy in the semen correlated with the number of PCV2b genomic copy in the blood in vaccinated and challenged boars (r(2)=0.894-0.926, P<0.01), and non-vaccinated and challenged boars (r(2)=0.903, P<0.01). The vaccination protocol reduced the amount of PCV2 DNA shed in the semen. However, there was a significantly different amount of PCV2 DNA shed in semen among the 3 vaccinated and challenged boar groups.
authors: Seoul National University, College of Veterinary Medicine, Department of Veterinary Pathology, 599 Gwanak-ro, Gwanak-gu, Seoul 151-742, Republic of Korea.
authors: Hwi Won
authors: HW
authors: Seo
authors: Kiwon
authors: K
authors: Han
authors: Yeonsu
authors: Y
authors: Oh
authors: Ikjae
authors: I
authors: Kang
authors: Changhoon
authors: C
authors: Park
authors: Chanhee
authors: C
authors: Chae
mesh_terms: D000818:Animals; D018173:Circoviridae Infections / Q000276:immunology* / Q000517:prevention & control; D017925:Circovirus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D008297:Male; D012661:Semen / Q000821:virology*; D013552:Swine; D013553:Swine Diseases / Q000276:immunology / Q000517:prevention & control / Q000821:virology; D014765:Viral Vaccines / Q000008:administration & dosage*; D014766:Viremia / Q000821:virology; D017201:Virus Shedding
chemical_list: D014765:Viral Vaccines