title: A self-adjuvanting supramolecular vaccine carrying a folded protein antigen.
abstract: This work illustrates a strategy for the design of molecularly defined immunotherapies, using a blend of supramolecular peptide self-assembly and active site-directed protein capture.
authors: Department of Surgery, University of Chicago, 5841 S. Maryland Ave. MC 5032, Chicago, IL 60637 USA; Department of Biomedical Engineering, Northwestern University, 2145 Sheridan Road, Tech M292, Evanston, IL 60208-3109 USA.
authors: Gregory A
authors: GA
authors: Hudalla
authors: Justin A
authors: JA
authors: Modica
authors: Ye F
authors: YF
authors: Tian
authors: Jai S
authors: JS
authors: Rudra
authors: Anita S
authors: AS
authors: Chong
authors: Tao
authors: T
authors: Sun
authors: Milan
authors: M
authors: Mrksich
authors: Joel H
authors: JH
authors: Collier
mesh_terms: D000276:Adjuvants, Immunologic; D000595:Amino Acid Sequence; D000818:Animals; D000906:Antibodies / Q000097:blood / Q000276:immunology; D000941:Antigens / Q000737:chemistry* / Q000276:immunology; D049452:Green Fluorescent Proteins / Q000737:chemistry / Q000276:immunology; D051379:Mice; D008810:Mice, Inbred C57BL; D057139:Nanofibers / Q000737:chemistry; D009596:Nitrophenols / Q000737:chemistry; D063065:Organophosphonates / Q000737:chemistry; D010455:Peptides / Q000737:chemistry* / Q000276:immunology; D014614:Vaccines, Synthetic / Q000737:chemistry* / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D000906:Antibodies; D000941:Antigens; D009596:Nitrophenols; D063065:Organophosphonates; D010455:Peptides; D014614:Vaccines, Synthetic; D049452:Green Fluorescent Proteins; C085778:4-nitrophenyl phosphonate
keywords: biomolecular materials; immunotherapy; nanofibers; proteins; self-assembly