title: Metastatic mediastinal carcinoid presenting as superior mediastinal syndrome and treated with peptide receptor radionuclide therapy.
abstract: A 43-year-old man with known superior mediastinal syndrome due to (99m)Tc HYNIC DOTA SPECT/CT and (18)F-FDG PET tracer avid inoperable metastatic carcinoid received peptide receptor based radionuclide therapy (PRRT) with (177)Lu-DOTATATE. Repeat evaluation at 3 months post-therapy demonstrated stable disease with alleviation of patient's symptoms and remarkable improvement in the quality of life. PRRT with (177)Lu-DOTATATE may be an option for inoperable mediastinal carcinoids with superior mediastinal syndrome.
authors: From the Radiation Medicine Centre, Parel, Mumbai, India.
authors: Gaurav
authors: G
authors: Malhotra
authors: Ramesh V
authors: RV
authors: Asopa
mesh_terms: D000328:Adult; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy*; D008482:Mediastinum / Q000000981:diagnostic imaging*; D009362:Neoplasm Metastasis; D049268:Positron-Emission Tomography; D018000:Receptors, Peptide / Q000378:metabolism*; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D018000:Receptors, Peptide