title: Study of polycyclic aromatic hydrocarbon contamination of major rivers in the Czech Republic using biliary metabolite in chub, Leuciscus cephalus L.
abstract: The aim of the present study was to evaluate polycyclic aromatic hydrocarbon (PAH) contamination of the major rivers in the Czech Republic using 1-hydroxypyrene (1-OHP) content in chub bile as a biomarker. The highest concentration of 1-OHP was found in the Otava River at Topělec (80.5 ng mg protein(-1)); the lowest content of 1-OHP was found in the Vltava at Zelčín (9.6 ng mg protein(-1)). At all sites, bottom sediment samples were collected and analyzed for PAH content. The PAH content ranged between 1.2 and 15.2 mg kg dry mass(-1) at all sites. Statistically significant positive correlations (p < 0.05) between biliary 1-OHP and sediment PAH content were found. Correlation coefficients for total and individual priority PAHs ranged from 0.63 to 0.77.
authors: Department of Veterinary Public Health and Toxicology, University of Veterinary and Pharmaceutical Sciences Brno, Palackeho tr. 1/3, 612 42 Brno, Czech Republic. blahovaj@vfu.cz
authors: Jana
authors: J
authors: Blahova
authors: Drahomira
authors: D
authors: Leontovycova
authors: Vit
authors: V
authors: Kodes
authors: Zdenka
authors: Z
authors: Svobodova
mesh_terms: D000818:Animals; D001646:Bile / Q000378:metabolism; D015415:Biomarkers / Q000378:metabolism; D003530:Cyprinidae; D018153:Czech Republic; D004784:Environmental Monitoring / Q000379:methods*; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis*; D011721:Pyrenes / Q000378:metabolism; D045483:Rivers / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D015415:Biomarkers; D011084:Polycyclic Aromatic Hydrocarbons; D011721:Pyrenes; D014874:Water Pollutants, Chemical; C033146:1-hydroxypyrene