title: A Multiple Indicators Multiple Cause (MIMIC) model of respiratory health and household factors in Chinese children: the seven Northeastern cities (SNEC) study.
abstract: In China, with the rapid economic development and improvement of living standards over the past few decades, the household living environment has shifted dramatically. The aim of the present study is to assess the impact of home environment factors on respiratory symptoms and asthma in Chinese children. Investigators analyzed data collected in the 25 districts from the seven Northeastern cities to examine health effects on respiratory symptoms and asthma in 31,049 children aged 2-14 years. Factor analysis was used to reduce 33 children's lifestyle and household variables to six new 'factor' variables. The multiple indicators multiple causes approach was used to examine the relationship between indoor air pollution and respiratory health status, controlling for covariates. Factor analyses generated six factor variables of potential household risk factors from an original list of 33 variables. The respiratory symptoms and asthma were significantly associated with the recent home renovation factor (estimate = 0.076, p < 0.001), pet ownership factor (estimate = 0.095, p < 0.001), environmental tobacco smoke (ETS) exposure factor (estimate = 0.181, p < 0.001) and PVC-flooring factor (estimate = 0.031, p = 0.007). Home ventilation factor was not related to any respiratory condition (estimate = 0.028, p = 0.074). Independent respiratory health effects existed for multiple household environmental factors recent home renovation, pet ownership, ETS, and PVC-flooring.
authors: Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, 110001, Liaoning Province, People's Republic of China.|Department of Occupational and Environmental Health, School of Public Health, China Medical University, Shenyang, 110001, Liaoning Province, People's Republic of China.
authors: Guang-Hui
authors: GH
authors: Dong
authors: Department of Epidemiology, School of Public Health, Saint Louis University, Salus Center/Room 473, 3545 Lafayette Avenue, Saint Louis, MO, 63104, USA. zqian2@slu.edu.
authors: Zhengmin
authors: Z
authors: Qian
authors: Department of Biostatistics, School of Public Health, Saint Louis University, Saint Louis, MO, 63104, USA.
authors: Qiang
authors: Q
authors: Fu
authors: Department of Biostatistics, School of Public Health, Saint Louis University, Saint Louis, MO, 63104, USA.
authors: Jing
authors: J
authors: Wang
authors: Department of Epidemiology, School of Public Health, Saint Louis University, Salus Center/Room 473, 3545 Lafayette Avenue, Saint Louis, MO, 63104, USA.
authors: Edwin
authors: E
authors: Trevathan
authors: Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, 510300, Guangdong Province, People's Republic of China.
authors: Wenjun
authors: W
authors: Ma
authors: Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, 110001, Liaoning Province, People's Republic of China.|Department of Occupational and Environmental Health, School of Public Health, China Medical University, Shenyang, 110001, Liaoning Province, People's Republic of China.
authors: Miao-Miao
authors: MM
authors: Liu
authors: Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, 110001, Liaoning Province, People's Republic of China.|Department of Occupational and Environmental Health, School of Public Health, China Medical University, Shenyang, 110001, Liaoning Province, People's Republic of China.
authors: Da
authors: D
authors: Wang
authors: Department of Ambient Air Pollution Monitor, Shenyang Environmental Monitoring Center, Shenyang, 110014, Liaoning Province, People's Republic of China.
authors: Wan-Hui
authors: WH
authors: Ren
authors: Department of Environmental and Occupational Health, School of Public Health, Saint Louis University, Saint Louis, MO, 63104, USA.
authors: Kee-Hean
authors: KH
authors: Ong
authors: Department of Epidemiology, School of Public Health, Louisiana State University, New Orleans, LA, 70112, USA.
authors: Tekeda Freeman
authors: TF
authors: Ferguson
authors: Department of Epidemiology, School of Public Health, Saint Louis University, Salus Center/Room 473, 3545 Lafayette Avenue, Saint Louis, MO, 63104, USA.
authors: Erin
authors: E
authors: Riley
authors: Department of Epidemiology, School of Public Health, Saint Louis University, Salus Center/Room 473, 3545 Lafayette Avenue, Saint Louis, MO, 63104, USA.
authors: Maayan
authors: M
authors: Simckes
mesh_terms: D016902:Air Pollution, Indoor / Q000009:adverse effects*; D002648:Child; D002681:China / Q000453:epidemiology; D003296:Cooking / Q000295:instrumentation / Q000379:methods; D003430:Cross-Sectional Studies; D005163:Factor Analysis, Statistical; D005260:Female; D006798:Housing / Q000706:statistics & numerical data* / Q000639:trends; D006801:Humans; D007374:Interior Design and Furnishings; D008297:Male; D057805:Pets / Q000276:immunology; D012044:Regression Analysis; D012130:Respiratory Hypersensitivity / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*; D014504:Urban Health / Q000706:statistics & numerical data
chemical_list: D014028:Tobacco Smoke Pollution