title: Synthesis of 3-cyanoindole derivatives mediated by copper(I) iodide using benzyl cyanide.
abstract: Copper-mediated direct and regioselective C3-cyanation of indoles using benzyl cyanide as the cyanide anion source is presented. A wide range of indoles undergo cyanation smoothly by employing a reaction system of copper(I) iodide under open-to-air vessels.
authors: State Key Laboratory of Chirosciences and Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
authors: On Ying
authors: OY
authors: Yuen
authors: Pui Ying
authors: PY
authors: Choy
authors: Wing Kin
authors: WK
authors: Chow
authors: Wing Tak
authors: WT
authors: Wong
authors: Fuk Yee
authors: FY
authors: Kwong
mesh_terms: D000097:Acetonitriles / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D007454:Iodides / Q000737:chemistry*; D015394:Molecular Structure; D009570:Nitriles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: C583553:3-cyanoindole; D000097:Acetonitriles; D007211:Indoles; D007454:Iodides; D009570:Nitriles; C006725:benzyl cyanide; D003300:Copper; C073870:cuprous iodide