title: Chemoselective hydrogenation reaction of unsaturated bonds in the presence of an o-nitrobenzenesulfonyl group.
abstract: Chemoselective hydrogenation of unsaturated compounds bearing an o-nitrobenzenesulfonyl (Ns)-amide moiety, affording the corresponding saturated compounds, was accomplished efficiently without loss of the nitro group by using the Pd/MS3A catalyst and a H2 balloon. Partial hydrogenation of alkynes bearing an Ns group to corresponding cis alkenes was achieved with the combination of the Pd/BN catalyst and an additive (diethylenetriamine or acetic acid).
authors: School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
authors: Akinori
authors: A
authors: Kawanishi
authors: Chiyako
authors: C
authors: Miyamoto
authors: Yuki
authors: Y
authors: Yabe
authors: Makoto
authors: M
authors: Inai
authors: Tomohiro
authors: T
authors: Asakawa
authors: Yoshitaka
authors: Y
authors: Hamashima
authors: Hironao
authors: H
authors: Sajiki
authors: Toshiyuki
authors: T
authors: Kan
mesh_terms: D000480:Alkynes / Q000737:chemistry; D000577:Amides / Q000737:chemistry; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006865:Hydrogenation; D015394:Molecular Structure; D009578:Nitrobenzenes / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D013450:Sulfones / Q000737:chemistry*
chemical_list: D000480:Alkynes; D000577:Amides; D009578:Nitrobenzenes; D013450:Sulfones; D010165:Palladium