title: Retinal degenerative diseases--mechanisms and perspectives of treatment.
abstract: Retinal degenerative diseases are an extensive group of ocular diseases, leading to vision disorders and finally irreversible vision loss. They are an significant problem, because degenerative processes exist in common ocular disorders like glaucoma or age-related macular degeneration and many other less frequently occurring disorders. In this article, we present mechanisms leading to retinal degeneration like excitotoxicity, oxidative stress, inflammation and summarize the latest reports concerning neuroprotection in the treatment of retina degenerative diseases.
authors: Department of General Ophthalmology, Medical University of Lublin, Lublin, Poland. robertrejdak@yahoo.com
authors: Robert
authors: R
authors: Rejdak
authors: Małgorzata
authors: M
authors: Szkaradek
authors: Maciej
authors: M
authors: Czepita
authors: Wesam
authors: W
authors: Taslaq
authors: Aneta
authors: A
authors: Lewicka-Chomont
authors: Paweł
authors: P
authors: Grieb
mesh_terms: D000375:Aging; D006801:Humans; D007249:Inflammation / Q000150:complications*; D018696:Neuroprotective Agents / Q000627:therapeutic use; D009498:Neurotoxins / Q000633:toxicity; D018384:Oxidative Stress; D017382:Reactive Oxygen Species / Q000378:metabolism; D012162:Retinal Degeneration / Q000209:etiology / Q000378:metabolism* / Q000517:prevention & control / Q000628:therapy*
chemical_list: D018696:Neuroprotective Agents; D009498:Neurotoxins; D017382:Reactive Oxygen Species