title: Placenta-derived microparticles.
abstract: Microparticles (MPs), sub-micron membrane vesicles, participate in the placental and maternal crosstalk in normal pregnancies as well as in gestational vascular complications (GVC). The article will review the effects of MPs on placental physiological processes, including hemostasis, trophoblast migration, invasion, placental vasculature and their involvement in pathologic states such as thrombosis, inflammation and endothelial dysfunction, resulting in GVC.
authors: Thrombosis & Hemostasis Unit, Rambam Health Care Campus and Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology Haifa, Israel. a_aharon@rambam.health.gov.il
authors: Anat
authors: A
authors: Aharon
authors: Benjamin
authors: B
authors: Brenner
mesh_terms: D002465:Cell Movement; D055252:Cell-Derived Microparticles / Q000502:physiology*; D004730:Endothelium, Vascular / Q000503:physiopathology; D005260:Female; D005342:Fibrinolysis; D006487:Hemostasis; D006801:Humans; D007249:Inflammation / Q000503:physiopathology; D009389:Neovascularization, Pathologic; D010743:Phospholipids / Q000378:metabolism; D010920:Placenta / Q000098:blood supply / Q000502:physiology* / Q000503:physiopathology*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000503:physiopathology; D013927:Thrombosis / Q000503:physiopathology; D014327:Trophoblasts / Q000166:cytology; D014652:Vascular Diseases / Q000503:physiopathology
chemical_list: D010743:Phospholipids