title: Pulmonary fibrosis presenting as an early manifestation of microscopic polyangiitis.
abstract: Microscopic polyangiitis (MPA) is a systemic small vessel vasculitis that is included in the pulmonary-renal syndromes. Although glomerulonephritis represents the major clinical feature of MPA indicative of renal involvement, diffuse alveolar haemorrhage is the classic manifestation of pulmonary involvement. However, pulmonary fibrosis is a less frequently reported pulmonary manifestation. Herein we describe a patient who was diagnosed with MPA presenting with radiographic evidence of pulmonary interstitial fibrosis as an early clinical manifestation accompanied by constitutional symptoms such as fever and weight loss. We also include a short literature review focusing on the association between pulmonary fibrosis and MPA.
authors: Department of Pneumonology, Army General Hospital of Athens, Athens, Greece.
authors: D
authors: D
authors: Eleftheriou
authors: S
authors: S
authors: Katsenos
authors: S
authors: S
authors: Zorbas
authors: I
authors: I
authors: Griveas
authors: K
authors: K
authors: Psathakis
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D055953:Microscopic Polyangiitis / Q000150:complications*; D011658:Pulmonary Fibrosis / Q000209:etiology*