title: Neuroblastoma in an adult: case presentation and literature review.
abstract: Neuroblastoma is the most common malignancy in children less than one year of age, but is rare in adults. Adult neuroblastoma differs from pediatric cases by lacking classical features including low incidence of MYCN amplification, elevated urinary catecholamimes, and MIBG avidity. The diagnosis may not be initially considered because of the rarity, which emphasizes the importance of immunohistochemical staining and cytogenetic testing in aiding the diagnosis. We present a case of neuroblastoma in a 39-year-old woman who failed to respond to intensive therapy for this malignancy and died within a year after diagnosis.
authors: Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
authors: Laura
authors: L
authors: Smith
authors: Steve
authors: S
authors: Minter
authors: Paul
authors: P
authors: O'Brien
authors: Jacqueline M
authors: JM
authors: Kraveka
authors: Ana Maria
authors: AM
authors: Medina
authors: John
authors: J
authors: Lazarchick
mesh_terms: D000328:Adult; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009447:Neuroblastoma / Q000473:pathology*