title: The effectiveness of early treatment in segmental vitiligo: retrospective study according to disease duration.
abstract: Segmental vitiligo (SV) is usually characterized by a unilateral-dermatomal distribution, earlier onset and rapid progression followed by stabilization. The response to phototherapy in patients with SV is limited. We evaluated the treatment response in 39 cases of SV according to disease duration. Ten cases (50.0%) of Group 1 (duration ≤ 5 months) and five cases (26.3%) of Group 2 (duration > 5 months) showed more than 50% repigmentation. Contrary to previous reports, patients in our study responded well to medical treatments like oral steroids, topical calcineurin inhibitors and phototherapy when treated early after onset. The results suggest that early treatment is important.
authors: Department of Dermatology, Kangbuk Samsung Hospital, Seoul, Korea.
authors: Ji-Hye
authors: JH
authors: Park
authors: Se Won
authors: SW
authors: Park
authors: Dong-Youn
authors: DY
authors: Lee
authors: Joo-Heung
authors: JH
authors: Lee
authors: Jun-Mo
authors: JM
authors: Yang
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010789:Phototherapy; D012189:Retrospective Studies; D013256:Steroids / Q000627:therapeutic use; D016559:Tacrolimus / Q000627:therapeutic use; D013997:Time Factors; D014820:Vitiligo / Q000628:therapy*; D055815:Young Adult
chemical_list: D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D013256:Steroids; D016559:Tacrolimus