title: One-year follow-up of femtosecond laser-assisted penetrating keratoplasty.
abstract: BACKGROUND
  The purpose of this report is to describe the initial outcomes of femtosecond laser-assisted penetrating keratoplasty.
  
  
  METHODS
  This retrospective surgical case series consisted of 10 eyes from 10 patients undergoing penetrating keratoplasty at a tertiary center. Femtosecond laser was used to perform a zig-square incision on the donor cornea with matched dimensions on the recipient cornea. Outcomes measured included: unaided visual acuity and best spectacle-corrected visual acuity preoperatively and at one, 3, 6, and 12 months postoperatively; manifest refractive and topographic astigmatism at 3, 6, and 12 months postoperatively; and endothelial cell density loss, calculated at the end of the one-year follow-up period.
  
  
  RESULTS
  At one-year follow-up, there was an improvement in unaided visual acuity from a mean preoperative logMAR of 1.67 to 0.44, and best spectacle-corrected visual acuity from a mean preoperative logMAR of 1.33 to 0.13. By postoperative month 3, mean manifest refractive and topographic astigmatism was 2.31 ± 1.41 D and 2.59 ± 1.57 D, respectively. The mean reduction in endothelial cell density was 20.7% after one year of follow-up.
  
  
  CONCLUSIONS
  Femtosecond laser-assisted penetrating keratoplasty provided a good visual outcome and early visual rehabilitation due to precise graft-host alignment and reduced astigmatism in the early postoperative months.
authors: National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore.
authors: Johnson Choon-Hwai
authors: JC
authors: Tan
authors: Wee-Jin
authors: WJ
authors: Heng
keywords: femtosecond laser-assisted keratoplasty; penetrating keratoplasty