title: Photophysics and light-activated biocidal activity of visible-light-absorbing conjugated oligomers.
abstract: The photophysical properties of three cationic π-conjugated oligomers were correlated with their visible light activated biocidal activity vs S. aureus. The oligomers contain three arylene units (terthiophene, 4a; thiophene-benzotriazole-thiophene, 4b; thiophene-benzothiadiazole-thiophene, 4c) capped on each end by cationic -(CH2)3NMe3(+) groups. The oligomers absorb in the visible region due to their donor-acceptor-donor electronic structure. Oligomers 4a and 4b have high intersystem crossing and singlet oxygen sensitization efficiency, but 4c has a very low intersystem crossing efficiency and it does not sensitize singlet oxygen. The biocidal activity of the oligomers under visible light varies in the order 4a > 4b ≈ 4c.
authors: Anand
authors: A
authors: Parthasarathy
authors: Subhadip
authors: S
authors: Goswami
authors: Thomas S
authors: TS
authors: Corbitt
authors: Eunkyung
authors: E
authors: Ji
authors: Dimitri
authors: D
authors: Dascier
authors: David G
authors: DG
authors: Whitten
authors: Kirk S
authors: KS
authors: Schanze
mesh_terms: D001424:Bacterial Infections / Q000517:prevention & control*; D004202:Disinfectants / Q000737:chemistry*; D024881:Drug Resistance, Bacterial; D006801:Humans; D008027:Light; D055668:Photochemical Processes; D011108:Polymers / Q000737:chemistry*; D026082:Singlet Oxygen / Q000737:chemistry*; D013876:Thiophenes / Q000737:chemistry*
chemical_list: D004202:Disinfectants; D011108:Polymers; D013876:Thiophenes; D026082:Singlet Oxygen