title: Extrinsic aging: UV-mediated skin carcinogenesis.
abstract: Age-associated skin lesions linked to UV radiation (UVR) include actinic keratosis, non-melanoma skin cancer-such as basal cell carcinoma and squamous cell carcinoma-lentigo senilis and lentigo maligna. Their incidence is increasing worldwide, mainly due to exaggerated UV exposure and to an aging population. Early diagnosis and therapy of pre-malignant cutaneous lesions is crucial for the secondary prophylaxis of invasive and highly aggressive skin cancers. Combined efforts to increase public awareness, patient education about self-examination, prophylactic modalities, such as consistent and sufficient UV protection, and rigorous follow-up of high-risk groups are of highest importance.
authors: Second Department of Dermatology and Venereology; Papageorgiou Hospital; Aristotle University School of Medicine; Thessaloniki, Greece.
authors: Fragkiski
authors: F
authors: Tsatsou
authors: Myrto
authors: M
authors: Trakatelli
authors: Aikaterini
authors: A
authors: Patsatsi
authors: Konstantinos
authors: K
authors: Kalokasidis
authors: Dimitrios
authors: D
authors: Sotiriadis
keywords: actinic keratosis; basal cell carcinoma; carcinogenesis; field cancerization; lentigo maligna; photoprotection; skin aging; skin cancer; squamous cell carcinoma