title: Identification of kakusei, a nuclear non-coding RNA, as an immediate early gene from the honeybee, and its application for neuroethological study.
abstract: The honeybee is a social insect that exhibits various social behaviors. To elucidate the neural basis of honeybee behavior, we detected neural activity in freely-moving honeybee workers using an immediate early gene (IEG) that is expressed in a neural activity-dependent manner. In European honeybees (Apis mellifera), we identified a novel nuclear non-coding RNA, termed kakusei, as the first insect IEG, and revealed the neural activity pattern in foragers. In addition, we isolated a homologue of kakusei, termed Acks, from the Japanese honeybee (Apis cerana), and detected active neurons in workers fighting with the giant hornet.
authors: Division of Life Sciences, Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192, Japan. kiya@staff.kanazawa-u.ac.jp.
authors: Taketoshi
authors: T
authors: Kiya
authors: Atsushi
authors: A
authors: Ugajin
authors: Takekazu
authors: T
authors: Kunieda
authors: Takeo
authors: T
authors: Kubo
mesh_terms: D000818:Animals; D001516:Bees / Q000235:genetics / Q000378:metabolism*; D017344:Genes, Insect / Q000502:physiology*; D009474:Neurons / Q000166:cytology / Q000378:metabolism*; D015138:RNA, Nuclear / Q000235:genetics / Q000378:metabolism*; D022661:RNA, Untranslated / Q000235:genetics / Q000378:metabolism*
chemical_list: D015138:RNA, Nuclear; D022661:RNA, Untranslated