title: Incidental gall bladder carcinoma in laparoscopic cholecystectomy: a report of 6 cases and a review of the literature.
abstract: BACKGROUND
  Gall bladder carcinoma accounts for 98% of all the gall bladder malignancies and it is the sixth most common malignancy of the gastrointestinal tract worldwide. The incidence of incidental gall bladder carcinoma which is diagnosed during or after a laparoscopic cholecystectomy is reported to be around 0.19-3.3% in the literature.
  
  
  OBJECTIVE
  This study was aimed at detecting the incidence of gall bladder carcinomas which were diagnosed incidentally during or after laparoscopic cholecystectomies which were done for gall stone disease and cholecystitis.
  
  
  METHODS
  We analyzed the medical records of patients with symptomatic gallstone disease and acute or chronic cholecystitis, who underwent laparoscopic cholecystectomies at the Hakeem Abdul Hameed Centenary Hospital during the period from January 2007 to June 2012.
  
  
  RESULTS
  A total of 622 laparoscopic cholecystectomies were performed at our institute during the study period of five and a half years. In 6 (0.96%) cases, incidental carcinomas of the gallbladder were discovered.
  
  
  CONCLUSIONS
  A laparoscopic cholecystectomy which is performed for benign gall bladder disease rarely results in a diagnosis of unexpected gallbladder cancer. The microscopic examination of the specimens, with special attention to the depth of invasion, range of the mucosal spread and the lymphovascular involvement, is critical in diagnosing the incidental malignancies as well as for the subsequent management of the cases.
authors: Associate Professor, Department of Pathology, HIMSR , New Delhi, India .
authors: Jetley
authors: J
authors: Sujata
authors: Rana
authors: R
authors: S
authors: Khan
authors: K
authors: Sabina
authors: Hassan
authors: H
authors: Mj
authors: Zeeba Shamim
authors: ZS
authors: Jairajpuri
keywords: Carcinoma; Gall bladder; Incidental