title: The Pauson-Khand reaction of medium sized trans-cycloalkenes.
abstract: Medium sized trans-cycloalkenes are unusually reactive in the intermolecular Pauson-Khand reaction (PKR) with regard to typical monocyclic alkenes. This is due to the ring strain imparted by the E stereochemistry. The PKR of these alkenes offers a modular, regioselective and straightforward entry to trans fused [n.3.0] bicyclic scaffolds (n = 6-8).
authors: Institute for Research in Biomedicine (IRB Barcelona), Baldiri Reixac 10, 08028 Barcelona, Spain. agusti.lledo@irbbarcelona.org
authors: Agustí
authors: A
authors: Lledó
authors: Aida
authors: A
authors: Fuster
authors: Marc
authors: M
authors: Revés
authors: Xavier
authors: X
authors: Verdaguer
authors: Antoni
authors: A
authors: Riera
mesh_terms: D000475:Alkenes / Q000737:chemistry; D000480:Alkynes / Q000737:chemistry; D001643:Bridged Bicyclo Compounds / Q000737:chemistry; D061565:Cycloaddition Reaction; D003516:Cycloparaffins / Q000737:chemistry*; D003517:Cyclopentanes / Q000737:chemistry; D007536:Isomerism
chemical_list: D000475:Alkenes; D000480:Alkynes; D001643:Bridged Bicyclo Compounds; D003516:Cycloparaffins; D003517:Cyclopentanes; C013905:cyclopentenone