title: Tranexamic acid: an important adjuvant in the treatment of melasma.
abstract: This article reviews an old drug tranexamic acid to its new use in the treatment of melasma. Its mechanism of preventing the activation of melanocyte from UV light, hormone and injured kerationcyte through the inhibition of the plasminogen activator system will be explored. The detail usage for such indication and its safety profile will also be thoroughly evaluated.
authors: tsz910@hotmail.com
authors: Tsz Wah
authors: TW
authors: Tse
authors: Edith
authors: E
authors: Hui
mesh_terms: D000284:Administration, Oral; D001205:Ascorbic Acid / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006801:Humans; D008548:Melanosis / Q000188:drug therapy*; D014148:Tranexamic Acid / Q000627:therapeutic use*; D016896:Treatment Outcome; D014803:Vitamin B Complex / Q000627:therapeutic use; D014810:Vitamin E / Q000627:therapeutic use; D014815:Vitamins / Q000627:therapeutic use
chemical_list: D003879:Dermatologic Agents; D014815:Vitamins; D014803:Vitamin B Complex; D014810:Vitamin E; D014148:Tranexamic Acid; D001205:Ascorbic Acid