title: [Study on the chemical constituents of the active fraction of Polygonum capitatum].
abstract: OBJECTIVE
  To investigate the chemical constituents of the active fraction of Polygonum capitatum.
  
  
  METHODS
  Various preparative chromatographic techniques were used for the isolation and purification of the compounds in the flavonoid-enriched fraction and their structures were determined by comparison of their physicochemical and chromatographic data with those of the authentic samples and spectral analysis.
  
  
  RESULTS
  Fourteen compounds were obtained and identified as 1-O-P-D-(6'-O-galloyl)-glucopyranosyl-3-methoxy-5-hydroxybenzene (1) ,5,7-dihydroxy-4H-chromen-4-one (2), ellagic acid (3), myricetrin (4), hirsutine (5), rutin (6), quercetin-3-O-(2"-O-galloyl)-beta-D-glucopyranoside (7) , quercetin-3-O-( 3"-O-galloyl) -/3-D-glucopyranoside (8), quercitrin (9) , kaempferol-3-O-alpha-L-rhamnopyranoside (10), quercetin-3-O-(2"-O-galloyl) -alpha-L-rhamnopyranoside (11), quercetin-3-O-(3"-O-galloyl) -alpha-L-rhamnopyranoside (12), quercetin (13), kaempferol (14).
  
  
  CONCLUSIONS
  The flavonoid-enriched fraction contains flavonols and their glycosides as its major components,which might be responsible for the biological effects of Polygonum capitatum. Compounds 1, 8 and 12 are isolated from the genus Polygonum for the first time; Compound 3 is isolated from Polygonum capitatum for the first time.
authors: Provincial Key Laboratory of Pharmaceutics in Guizhou Province, Guiyang 550004, China.
authors: Li-juan
authors: LJ
authors: Zhang
authors: Yong-lin
authors: YL
authors: Wang
authors: Zhen
authors: Z
authors: Wang
authors: Yong-jun
authors: YJ
authors: Li
authors: Yon
authors: Y
authors: Huang
authors: Qing-de
authors: QD
authors: Long
authors: Shang-gao
authors: SG
authors: Liao
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D004610:Ellagic Acid / Q000032:analysis*; D005419:Flavonoids / Q000737:chemistry* / Q000302:isolation & purification; D015394:Molecular Structure; D010936:Plant Extracts / Q000032:analysis; D028502:Polygonum / Q000737:chemistry*
chemical_list: D004365:Drugs, Chinese Herbal; D005419:Flavonoids; D010936:Plant Extracts; D004610:Ellagic Acid