title: Pharmacological inhibition of stearoyl CoA desaturase in the skin induces atrophy of the sebaceous glands.
authors: Josef G
authors: JG
authors: Meingassner
authors: Heinrich
authors: H
authors: Aschauer
authors: Anthony P
authors: AP
authors: Winiski
authors: Natalie
authors: N
authors: Dales
authors: David
authors: D
authors: Yowe
authors: Michael D
authors: MD
authors: Winther
authors: Zaihui
authors: Z
authors: Zhang
authors: Anton
authors: A
authors: Stütz
authors: Andreas
authors: A
authors: Billich
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy* / Q000201:enzymology / Q000473:pathology; D000818:Animals; D001284:Atrophy; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D056945:Hep G2 Cells; D006801:Humans; D051379:Mice; D008815:Mice, Inbred Strains; D010879:Piperazines / Q000737:chemistry / Q000494:pharmacology*; D011724:Pyridazines / Q000737:chemistry / Q000494:pharmacology*; D012627:Sebaceous Glands / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D013230:Stearoyl-CoA Desaturase / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: C583719:6-(4-(5-fluoro-2-trifluoromethylbenzoyl)piperazin-1-yl)pyridazine-3-carboxylic acid (2-cyclopropylethyl)amide; D004791:Enzyme Inhibitors; D010879:Piperazines; D011724:Pyridazines; D013230:Stearoyl-CoA Desaturase