title: [Sitting and cardiovascular morbidity and mortality].
abstract: Prolonged sitting and sedentary behavior comprises a major part of the modern lifestyle: at work, leisure (watching television, Internet) and commuting/traveling. Studies have shown that adults spend about half of their time at work and even more sitting. Similarly, a significant part of the leisure time is spent doing sedentary activities usually in front of a screen (TV or a computer). However, current recommendations focus on increasing moderate-to-vigorous physical activity with almost no recommendations relating to sedentary activities. Recent evidence from several research papers showed deleterious relationships of sedentary behavior with cardiovascular risk factors (e.g., obesity, type 2 diabetes mellitus and waist circumference). Furthermore, consistent independent associations have been observed between sitting time/sedentary behaviors and elevated all-cause and cardiovascular disease mortality risk. Generally, these associations have persisted following adjustment for physical activity. Recent emerging findings have shown that breaking up sedentary time potentially has a beneficial impact on cardiovascular health (independent of total sedentary time and moderate-to-vigorous intensity activity). In this article, we review the association between the time spent in various sedentary activities (occupational, leisure and commuting/transportation) and cardiovascular risk factors and cardiovascular morbidity and mortality. In addition, we review the suggested mechanisms that explain the empiric associations.
authors: Department of Cardiology, Barzilai Medical Center, Ashkelon Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. Arthur.shiyovich@gmail.com
authors: Arthur
authors: A
authors: Shiyovich
authors: Vladimir
authors: V
authors: Shlyakhover
authors: Amos
authors: A
authors: Katz
mesh_terms: D000328:Adult; D002318:Cardiovascular Diseases / Q000209:etiology / Q000401:mortality / Q000503:physiopathology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D006801:Humans; D007899:Leisure Activities; D009043:Motor Activity / Q000502:physiology; D009765:Obesity / Q000150:complications; D012307:Risk Factors; D057185:Sedentary Behavior; D013997:Time Factors; D055105:Waist Circumference / Q000502:physiology