title: [Determination of doping in human urine by gas chromatography-high resolution mass spectrometry].
abstract: A method was evaluated for determination of twenty-one doping (including nandrolone, boldenone and methandienone) in human urine by gas chromatography-high resolution mass spectrometry. Samples were prepared by liquid-liquid extraction, concentrated, TMS derivatization and limit of detection at ng x mL(-1) by MID/GC/HRMS. According to the code of the World Anti-Doping Agency (WADA), precision and recoveries of the procedure were evaluated by replicate analysis (n = 6), the recoveries in the range of 66%-103%, with the RSD below 10.0%. The precision within the day of the method with three different concentrations was also determined RSD were less than 9.5%, 10.0% and 9.7%.
authors: China Anti-Doping Agency, Beijing 100029, China. xingyanyi@tom.com
authors: Yan-Yi
authors: YY
authors: Xing
authors: Xin
authors: X
authors: Liu
authors: Yu-Mei
authors: YM
authors: Zhang
authors: Xiao-Bing
authors: XB
authors: Wang
authors: You-Xuan
authors: YX
authors: Xu
mesh_terms: D045930:Anabolic Agents / Q000652:urine*; D004300:Doping in Sports; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008696:Methandrostenolone / Q000652:urine*; D009277:Nandrolone / Q000652:urine*; D015813:Substance Abuse Detection / Q000379:methods; D013739:Testosterone / Q000031:analogs & derivatives* / Q000652:urine
chemical_list: D045930:Anabolic Agents; D013739:Testosterone; C013915:boldenone; D009277:Nandrolone; D008696:Methandrostenolone