title: A new pentacyclic phenol and other constituents from the root bark of Bauhinia racemosa Lamk.
abstract: This work reported the isolation of one unknown (1) and 10 known compounds (2-11) from the root bark of Bauhinia racemosa Lamk. (family: Caesalpiniaceae). Racemosolone (1) was characterised as a pentacyclic phenolic compound possessing an unusual skeleton with a cycloheptane ring and a rare furopyran moiety. The structure elucidation was carried out on the basis of UV, infrared (IR), HR-ESI-MS, 1D and 2D NMR spectra and finally confirmed by the single crystal X-ray analysis. The known compounds were characterised as n-tetracosane, β-sitosteryl stearate, eicosanoic acid, stigmasterol, β-sitosterol, racemosol, octacosyl ferulate, de-O-methyl racemosol, lupeol and 1,7,8,12b-tetrahydro-2,2,4-trimethyl-2H-benzo[6,7]cyclohepta [1,2,3-de] [1] benzopyran-5,10,11 triol on the basis of spectroscopic data comparison with the literature value. Compounds with skeleton similar to 1 have never been reported from any natural or other source.
authors: a Department of Chemistry , University of Rajasthan , Jaipur , India.
authors: Renuka
authors: R
authors: Jain
authors: Namita
authors: N
authors: Yadav
authors: Teena
authors: T
authors: Bhagchandani
authors: Satish C
authors: SC
authors: Jain
mesh_terms: D036481:Bauhinia / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification*; D024301:Plant Bark / Q000737:chemistry*; D010936:Plant Extracts / Q000032:analysis*; D018517:Plant Roots / Q000737:chemistry*; D011083:Polycyclic Compounds / Q000737:chemistry / Q000302:isolation & purification*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D010636:Phenols; D010936:Plant Extracts; D011083:Polycyclic Compounds; C000589006:racemosolone