title: Effects of widely used drugs on micronutrients: a story rarely told.
abstract: Vitamins and trace elements are essential to the body, however, deficiencies are frequently observed in the general population. Diet is mostly responsible for these deficiencies but drugs also may play a significant role by influencing their metabolism. These effects are rarely assessed in clinical practice, in part because of limited data available in the literature. Drug-induced micronutrient depletions, however, may be the origin of otherwise unexplained symptoms that might sometimes influence medication compliance. We present various examples of widely prescribed drugs that can precipitate micronutrient deficiencies. This review aims at sensitizing physicians on drug-micronutrient interactions. High-risk population groups also are presented and supplementation protocols are suggested.
authors: Clinical Nutrition, Department of Medical Specialties, Geneva University Hospital, Geneva, Switzerland.
authors: Dimitrios
authors: D
authors: Samaras
authors: Nikolaos
authors: N
authors: Samaras
authors: Pierre-Olivier
authors: PO
authors: Lang
authors: Laurence
authors: L
authors: Genton
authors: Emilia
authors: E
authors: Frangos
authors: Claude
authors: C
authors: Pichard
mesh_terms: D000818:Animals; D003677:Deficiency Diseases / Q000139:chemically induced* / Q000178:diet therapy / Q000453:epidemiology / Q000517:prevention & control; D019587:Dietary Supplements; D018565:Food-Drug Interactions; D006801:Humans; D018977:Micronutrients / Q000008:administration & dosage / Q000172:deficiency / Q000378:metabolism* / Q000627:therapeutic use; D055553:Prescription Drugs / Q000009:adverse effects*; D012306:Risk
chemical_list: D018977:Micronutrients; D055553:Prescription Drugs