title: Emergence of large treatment effects from small trials--reply.
authors: John P A
authors: JP
authors: Ioannidis
authors: Tiago V
authors: TV
authors: Pereira
authors: Ralph I
authors: RI
authors: Horwitz
mesh_terms: D003627:Data Interpretation, Statistical; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome