title: Rapid multiexposure in vivo brain imaging system using vertical cavity surface emitting lasers as a light source.
abstract: We demonstrate an imaging technique implementing vertical cavity lasers with extremely low transient times for a greatly simplified realization of a multiexposure laser speckle contrast imaging system. Data from multiexposure laser speckle imaging was observed to more closely agree with absolute velocity measurements using time of flight technique, when compared to long-exposure laser speckle imaging. Furthermore, additional depth information of the vasculature morphology was inferred by accounting for the change in the static scattering from tissue above vessels with respect to the total scattering from blood flow and tissue.
authors: The Edward S. Rogers Sr. Department of Electrical and Computer Engineering, University of Toronto, Toronto, Ontario, Canada.
authors: Yaaseen
authors: Y
authors: Atchia
authors: Hart
authors: H
authors: Levy
authors: Suzie
authors: S
authors: Dufour
authors: Ofer
authors: O
authors: Levi
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D001921:Brain / Q000473:pathology*; D003952:Diagnostic Imaging / Q000379:methods; D007834:Lasers; D008027:Light; D008297:Male; D015233:Models, Statistical; D059906:Neuroimaging / Q000295:instrumentation* / Q000379:methods; D016011:Normal Distribution; D055095:Optics and Photonics; D051381:Rats; D017207:Rats, Sprague-Dawley; D012039:Regional Blood Flow; D012542:Scattering, Radiation