title: [Cytogenetic monitoring for assessment of human environmental safety].
abstract: Cytogenetic monitoring allows to identify groups and individuals with elevated levels of genomic instability, to determine the presence of genotoxic factors in the inspected area to justify the conduct of hygienic measures. An algorithm for cytogenetic monitoring with the usy of multi-organ karyological test, baseline of indices of cytogenetic effect, cell proliferation and apoptosis are presented, the index of accumulation of cytogenetic damage as a the basis for assessment of the three level of risk of cytogenetic abnormalities, is proposed.
authors: L P
authors: LP
authors: Sycheva
mesh_terms: D017209:Apoptosis / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D002478:Cells, Cultured; D020732:Cytogenetic Analysis / Q000379:methods*; D004784:Environmental Monitoring / Q000379:methods*; D004785:Environmental Pollutants / Q000633:toxicity*; D042822:Genomic Instability / Q000187:drug effects; D006801:Humans; D048629:Micronuclei, Chromosome-Defective / Q000139:chemically induced; D009061:Mouth Mucosa / Q000187:drug effects / Q000473:pathology; D009297:Nasal Mucosa / Q000187:drug effects / Q000473:pathology; D012107:Research Design; D012449:Safety; D019459:Urothelium / Q000187:drug effects / Q000473:pathology
chemical_list: D004785:Environmental Pollutants