title: In vitro tumor cytotoxic activities of extracts from three Liriodendron plants.
abstract: The extracts prepared from Liriodendron tulipifera Linn., L. chinense (Hemsl.) Sarg., and their hybrid L. chinense x L. tulipifera, were investigated for their cytotoxic abilities in vitro against five human cancer cell lines: MDA-MB-231 and MCF-7 breast cancer cells, SGC-7901 gastric cancer cells, HuH-7 hepatocarcinoma cells, and HCT-15 colon carcinoma cells, and then measured their phenols and alkaloids contents. Of these plant extracts, some of them, especially the lower polar extracts from barks, exhibited potent cytotoxic effects on five tested tumor cell lines.
authors: Nanjing Forestry University, Nanjing, China.
authors: Jin-Hui
authors: JH
authors: Chen
authors: Guo-Xu
authors: GX
authors: Yang
authors: Qiang
authors: Q
authors: Ding
authors: Tian-Song
authors: TS
authors: Xia
authors: Jisen
authors: J
authors: Shi
authors: Ai-Qun
authors: AQ
authors: Jia
mesh_terms: D000470:Alkaloids / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D006801:Humans; D020128:Inhibitory Concentration 50; D031567:Liriodendron / Q000737:chemistry*; D061986:MCF-7 Cells; D009369:Neoplasms / Q000473:pathology*; D010636:Phenols / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology*; D024301:Plant Bark; D010936:Plant Extracts / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology*; D018515:Plant Leaves; D010946:Plants, Medicinal
chemical_list: D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D010636:Phenols; D010936:Plant Extracts