title: ORE1 balances leaf senescence against maintenance by antagonizing G2-like-mediated transcription.
abstract: Leaf senescence is a key physiological process in all plants. Its onset is tightly controlled by transcription factors, of which NAC factor ORE1 (ANAC092) is crucial in Arabidopsis thaliana. Enhanced expression of ORE1 triggers early senescence by controlling a downstream gene network that includes various senescence-associated genes. Here, we report that unexpectedly ORE1 interacts with the G2-like transcription factors GLK1 and GLK2, which are important for chloroplast development and maintenance, and thereby for leaf maintenance. ORE1 antagonizes GLK transcriptional activity, shifting the balance from chloroplast maintenance towards deterioration. Our finding identifies a new mechanism important for the control of senescence by ORE1.
authors: University of Potsdam, Institute of Biochemistry and Biology, Karl-Liebknecht-Straße 24-25, Haus 20, Germany.
authors: Mamoona
authors: M
authors: Rauf
authors: Muhammad
authors: M
authors: Arif
authors: Hakan
authors: H
authors: Dortay
authors: Lilian P
authors: LP
authors: Matallana-Ramírez
authors: Mark T
authors: MT
authors: Waters
authors: Hong
authors: H
authors: Gil Nam
authors: Pyung-Ok
authors: PO
authors: Lim
authors: Bernd
authors: B
authors: Mueller-Roeber
authors: Salma
authors: S
authors: Balazadeh
mesh_terms: D017360:Arabidopsis / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000235:genetics / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant; D055786:Gene Knockout Techniques; D018515:Plant Leaves / Q000502:physiology*; D011485:Protein Binding; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D014158:Transcription, Genetic; D059467:Transcriptome; D020798:Two-Hybrid System Techniques
chemical_list: D029681:Arabidopsis Proteins; C468867:GLK1 protein, Arabidopsis; C468868:GLK2 protein, Arabidopsis; C538850:ORE1 protein, Arabidopsis; D014157:Transcription Factors