title: Large uterine neurofibroma.
abstract: Herein we report a rare case of a large uterine neurofibroma. The patient reported infertility and nonspecific pelvic symptoms. Physical examination and ultrasonography revealed a mass of uterine origin with echo texture similar to that of a myoma. With a provisional diagnosis of a myomatous uterus, laparoscopic myomectomy was attempted. The mass, which measured 13 × 9 × 8 cm, was noted to be arising from the uterine fundus and extending into the left broad ligament. Histopathologic examination revealed a neurofibroma, which was confirmed at immunohistochemical analysis of the specimen. Most neurofibromas arise as subcutaneous swellings, and large neurofibromas arising from the myometrium are rare. Deep-tissue neurofibromas are known to recur and are associated with a higher probability of becoming malignant.
authors: Centre for Fertility Care and Laparoscopic Surgery, Near Basel Mission Church, Hubli, Karnataka, India. segokavi@yahoo.com
authors: Shailesh Ernest
authors: SE
authors: Gokavi
authors: Ravikumar
authors: R
authors: Jadhav
authors: Purushotham
authors: P
authors: Reddy
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D010535:Laparoscopy; D009455:Neurofibroma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D055815:Young Adult