title: Changing prescribing patterns of type 2 diabetes medications from 2002-2010: an electronic health record-based evaluation.
abstract: BACKGROUND
  The implementation of electronic health records (EHRs) may support evaluations of health care delivery, such as        the prescription of newly approved medications, to adults with diabetes. We aimed to evaluate prescribing patterns of thiazolidinediones and novel glucose-lowering drug classes using electronic prescribing data contained in an outpatient EHR from 2002-2010.
  
  
  METHODS
  We identified adults with type 2 diabetes seen from 2002-2010 who were newly prescribed rosiglitazone (ROSI), pioglitazone (PIO), or a novel glucose-lowering drug class (other). The annual number of new prescriptions and their relative percentages (per 1000 patients) were calculated.
  
  
  RESULTS
  From 2002-2010, 6209 patients with type 2 diabetes were newly prescribed 8858 eligible medications. In 2006, ROSI and PIO accounted for 44% and 37% of new prescriptions, respectively. After 2007, the relative percentage of new ROSI prescriptions declined more rapidly than PIO prescriptions, falling to 7% and 47% of peak levels, respectively, by 2010. By 2010, the relative percentages of new ROSI, PIO, and other prescriptions were 2%, 18%, and 80%, respectively.
  
  
  CONCLUSIONS
  Evaluations of EHR data represent a cost-effective method for evaluating diabetes medications with new Food and Drug Administration warnings or indications. Validation of demographic and clinical data will expand the scope of EHR-based evaluations of health care delivery and outcomes for adults with diabetes.
authors: Section on Genetics and Epidemiology, Joslin Diabetes Center, Boston, Massachusetts 02215, USA. sanjeev.mehta@joslin.harvard.edu
authors: Sanjeev N
authors: SN
authors: Mehta
authors: Allison B
authors: AB
authors: Goldfine
authors: Martin J
authors: MJ
authors: Abrahamson
authors: Richard
authors: R
authors: DiVincenzo
authors: Lori M B
authors: LM
authors: Laffel
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D057286:Electronic Health Records; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D013997:Time Factors
chemical_list: D007004:Hypoglycemic Agents