title: Treatment of varus deformities of the lower limbs in patients with achondroplasia and hypochondroplasia.
abstract: Angular deformities of the lower limbs are a common clinical problem encountered in pediatric orthopaedic practices particularly in patients with osteochondrodysplasias. The varus deformity is more common than the valgus deformity in achondroplasia and hypochondroplasia patients because of the unusual growth of the fibulae than that of the tibiae. We retrospectively reviewed six patients (four patients with achondroplasia and two patients with hypochondroplsia) with relevant limb deformities due to the above-mentioned entities. All patients manifested significant varus deformity of the lower limbs. Detailed phenotypic characterization, radiologic and genetic testing was carried out as baseline diagnostic tool. We described the re-alignment procedures, which have been applied accordingly. Therefore, bilateral multi-level procedures, multi-apical planning and limb lengthening have been successfully applied. While recognition of the underlying syndromic association in patients who are manifesting angular deformities is the baseline for proper orthopaedic management, this paper demonstrates how to evaluate and treat these complex patients.
authors: Ludwig Boltzmann Institute of Osteology, at the Hanusch Hospital of WGKK and, AUVA Trauma Centre Meidling, First Medical Department, Hanusch Hospital, Vienna, Austria ; Orthopaedic Hospital of Speising, Paediatric Department, Vienna, Austria.
authors: Ali Al
authors: AA
authors: Kaissi
authors: Sebastian
authors: S
authors: Farr
authors: Rudolf
authors: R
authors: Ganger
authors: Jochen G
authors: JG
authors: Hofstaetter
authors: Klaus
authors: K
authors: Klaushofer
authors: Franz
authors: F
authors: Grill
keywords: Angular deformities; FGFR3 mutation.; achondroplasia; hypochondroplasia; limb lengthening; re-alignment procedures