title: Isolation of an σ-alkyl iridium hydride complex, formed in the (semi)hydrogenation of an β-enamido ketone.
abstract: σ-Alkyl iridium hydride complexes are generally postulated as intermediates in iridium-catalyzed hydrogenation. Fast reductive elimination results in the formation of the hydrogenation product. With an β-enamido ketone as unsaturated substrate, such an intermediate could be trapped because the semihydrogenated product coordinates trifold to the iridium, generating a stable 18e(-) complex, which does not eliminate.
authors: Institute for Organic Chemistry, Saarland University, Building C4.2, D-66123 Saarbruecken, Germany.
authors: Frauke
authors: F
authors: Maurer
authors: Uli
authors: U
authors: Kazmaier
mesh_terms: D006865:Hydrogenation; D007495:Iridium / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D007659:Ketones; D009942:Organometallic Compounds; D007495:Iridium