title: Use of medical aural and encephalic glue-soaked gelfoam for frontal sinus repair: a single-centre experience.
abstract: BACKGROUND
  Frontal sinus (FS) perforation is a common complication in frontal craniotomy. The primary goal of treatment is to seal the FS without destroying physiological function.
  
  
  OBJECTIVE
  This article describes a new FS cavity reconstruction technique using medical aural and encephalic glue (EC glue)-soaked gelfoam.
  
  
  METHODS
  Between 2007 and 2012, 118 patients underwent FS reconstruction using EC glue-soaked gelfoam. The FS cavity was reconstructed in all patients and no patient experienced intracranial infection, frontal sinusitis, or cerebrospinal fluid (CSF) leakage.
  
  
  RESULTS
  Restoring physiological function is the primary goal of FS reconstruction. Difficulty often arises in sealing the sinus opening, especially when the mucosa is damaged. Mucosal border dissection and electric coagulation of the mucosal laceration can help to reconstruct the mucosal cavity. Sealing the sinus with autogenous or exogenous material, such as fascia, bone flap or gelfoam carries increased risks of intracranial infection, frontal sinusitis, and CSF leakage in the short term, and increased the occurrence of a FS mucocoele in the long term. Gelfoam saturated with EC glue obtained good results.
  
  
  CONCLUSIONS
  We describe the application of gelfoam saturated with EC glue to treat an open FS with or without mucosal violation during frontal craniotomy. Gelfoam saturated with EC glue is a quick, effective, low-cost and reliable means of sealing the FS while preserving its physiological function.
authors: Department of Neurosurgery, First Affiliated Hospital, College of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou 310003, China.
authors: Heng-Jun
authors: HJ
authors: Zhou
authors: Ren-Ya
authors: RY
authors: Zhan
authors: Xiu-Jue
authors: XJ
authors: Zheng
authors: Gu
authors: G
authors: Li
authors: Fei
authors: F
authors: Cao
authors: Man-Tao
authors: MT
authors: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D065634:Cerebrospinal Fluid Leak; D002559:Cerebrospinal Fluid Rhinorrhea / Q000209:etiology; D003399:Craniotomy / Q000009:adverse effects; D004210:Dissection / Q000379:methods; D004564:Electrocoagulation / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D005624:Frontal Bone / Q000601:surgery; D005626:Frontal Sinus / Q000293:injuries / Q000601:surgery*; D015522:Frontal Sinusitis / Q000209:etiology; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use*; D006801:Humans; D007431:Intraoperative Complications; D008297:Male; D008875:Middle Aged; D009078:Mucocele / Q000209:etiology; D009297:Nasal Mucosa / Q000293:injuries / Q000601:surgery; D010254:Paranasal Sinus Diseases / Q000209:etiology; D011183:Postoperative Complications; D019651:Plastic Surgery Procedures / Q000379:methods*; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000209:etiology; D014014:Tissue Adhesives / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D014014:Tissue Adhesives
keywords: CSF; CT; EC glue; FS; Frontal sinus; Gelfoam; MRI; Medical aural and encephalic glue; Reconstruction; cerebrospinal fluid; computed tomography; frontal sinus; magnetic resonance imaging; medical aural and encephalic glue