title: High-dose argatroban for heparin-induced thrombocytopenia in a child using a ventricular assist device.
abstract: A 10-year-old boy who was receiving support from a ventricular assist device (VAD) experienced heparin-induced thrombocytopenia that was successfully treated with high-dose argatroban infusion to attain therapeutic activated partial thromboplastin time in spite of high serum argatroban levels. This case also highlights bolus argatroban dosing for VAD change in the setting of persistent ventricular fibrillation.
authors: Department of Pediatrics, Section of Pediatric Critical Care, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, AR 72205, USA.
authors: Sanjiv
authors: S
authors: Pasala
authors: Wesley A
authors: WA
authors: McKamie
authors: Michael L
authors: ML
authors: Schmitz
authors: Sherry C
authors: SC
authors: Faulkner
authors: Adnan T
authors: AT
authors: Bhutta
authors: Umesh
authors: U
authors: Dyamenahalli
authors: Takeshi
authors: T
authors: Shinkawa
authors: Michiaki
authors: M
authors: Imamura
authors: Parthak
authors: P
authors: Prodhan
mesh_terms: D002321:Career Choice; D016174:Hepacivirus; D019698:Hepatitis C, Chronic / Q000635:transmission*; D006801:Humans; D017758:Infectious Disease Transmission, Patient-to-Professional; D007396:Internship and Residency