title: Bioactive formulations with sugar-derived surfactants: a new approach for photoprotection and controlled release of promethazine.
abstract: Skin deep: A bioactive formulation for dermal delivery of antihistamines is obtained by using the original properties of catanionic associations towards self-assembly in water. The drug, which participates in its own transport, is preserved from photodegradation when solubilised in the bioactive formulation. The drug release through the skin is also delayed.
authors: Laboratoire IMRCP, UMR CNRS 5623, Université Paul Sabatier, 118 route de Narbonne, 31062 Toulouse cedex 9, France.
authors: Cécile
authors: C
authors: Bize
authors: Jean-Christophe
authors: JC
authors: Garrigues
authors: Jean-Pierre
authors: JP
authors: Corbet
authors: Isabelle
authors: I
authors: Rico-Lattes
authors: Muriel
authors: M
authors: Blanzat
mesh_terms: D018926:Anti-Allergic Agents / Q000008:administration & dosage; D004337:Drug Carriers / Q000737:chemistry; D005663:Furans / Q000008:administration & dosage; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy; D009005:Monosaccharides / Q000737:chemistry*; D011398:Promethazine / Q000008:administration & dosage; D011728:Pyridones / Q000008:administration & dosage; D012869:Skin Absorption; D013501:Surface-Active Agents / Q000737:chemistry*
chemical_list: D018926:Anti-Allergic Agents; D004337:Drug Carriers; D005663:Furans; D009005:Monosaccharides; D011728:Pyridones; D013501:Surface-Active Agents; C543575:bolaamphiphile; D011398:Promethazine