title: Inhibitory effects of the constituents of Hippophae rhamnoides on 3T3-L1 cell differentiation and nitric oxide production in RAW264.7 cells.
abstract: Three new flavonol glycosides, hippophaeosides A-C (1-3), together with 27 known constituents, were isolated from Hippophae rhamnoides L. leaves. Their structures were determined by spectroscopic analyses. Their inhibitory activities on 3T3-L1 preadipocyte differentiation and triglyceride accumulation in maturing adipocytes, and nitric oxide production in RAW264.7 cells were examined.
authors: School of Pharmacy, Nihon University, Funabashi, Chiba, Japan.
authors: Zhi-Gang
authors: ZG
authors: Yang
authors: Xiu-Feng
authors: XF
authors: Wen
authors: Yong-Hai
authors: YH
authors: Li
authors: Keiichi
authors: K
authors: Matsuzaki
authors: Susumu
authors: S
authors: Kitanaka
mesh_terms: D041721:3T3-L1 Cells; D017667:Adipocytes / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D002460:Cell Line; D044948:Flavonols / Q000737:chemistry* / Q000494:pharmacology*; D006027:Glycosides / Q000737:chemistry* / Q000494:pharmacology*; D031281:Hippophae / Q000737:chemistry*; D051379:Mice; D009569:Nitric Oxide / Q000096:biosynthesis* / Q000378:metabolism; D018515:Plant Leaves / Q000737:chemistry; D013057:Spectrum Analysis / Q000379:methods; D014280:Triglycerides / Q000378:metabolism
chemical_list: D044948:Flavonols; D006027:Glycosides; D014280:Triglycerides; D009569:Nitric Oxide