title: Isolated cortical vein thrombosis: a rare cause of venous stroke with good prognosis after timely diagnosis and treatment.
abstract: BACKGROUND
  Isolated cortical vein thrombosis (ICoVT) is a rare condition representing approximately 6% of cerebral vein thromboses (CVT). In all its forms, CVT is more prevalent in women. ICoVT shares the same group of predisposing conditions typical of other CVT. It may thus be easily missed due to its non-specific clinical presentation and confounding radiological findings, which may lead to a delay in appropriate diagnosis and treatment.
  
  
  METHODS
  A comprehensive literature search was conducted to identify manuscripts discussing epidemiology, risk factors, clinical presentation, radiological techniques and presentation, management, and outcome in patients with ICoVT.
  
  
  RESULTS
  We identified 40 papers published between 1991 and 2012 that met our criteria for review.
  
  
  CONCLUSIONS
  MR techniques are essential in the diagnosis of this entity. Without appropriate therapy, these thromboses may extend bidirectionally and even compromise the dural sinuses. Correction of predisposing factors for venous thrombosis and anticoagulation is the therapy of choice for most patients. The overall prognosis with adequate and timely therapy is very good.
authors: Department of Neurosurgery, Hadassah-Hebrew University Medical Center, Jerusalem 91120, Israel. jcohenns@yahoo.com
authors: José E
authors: JE
authors: Cohen
authors: Michaela
authors: M
authors: Duck
authors: John M
authors: JM
authors: Gomori
authors: Eyal
authors: E
authors: Itshayek
authors: Ronen R
authors: RR
authors: Leker
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D002550:Cerebral Veins / Q000000981:diagnostic imaging / Q000473:pathology*; D019468:Disease Management; D006801:Humans; D011379:Prognosis; D011859:Radiography; D020521:Stroke / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D020246:Venous Thrombosis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy*
chemical_list: D000925:Anticoagulants