title: Feasibility study of EUS-NOTES as a novel approach for peroral cholecysto-gastrostomy.
abstract: BACKGROUND
  EUS-guided cholecysto-gastrostomy might be a useful minimally invasive procedure used for salvage drainage in advanced pancreaticobiliary cancers, but also for drainage of the gallbladder in acute cholecystitis in patients deemed unfit for laparoscopic surgery.
  
  
  OBJECTIVE
  Direct EUS-guided cholecysto-gastrostomy with placement of a double flanged expandable metal stents.
  
  
  METHODS
  This was an animal pilot/feasibility study.
  
  
  METHODS
  The feasibility of EUS-guided cholecysto-gastrostomy through a transgastric approach was tested in five pigs. Specially designed EUS-guided devices for initial access in the gallbladder and a double flanged expandable metal stent were used in this study.
  
  
  RESULTS
  The results showed the feasibility of EUS-guided cholecysto-gastrostomy based on prototype devices for access in the gallbladder and transgastric stent placement.
  
  
  CONCLUSIONS
  Survival feasibility study with prototype devices in a small number of animals.
  
  
  CONCLUSIONS
  EUS guided cholecysto-gastrostomy in a porcine model is feasible but technically demanding due to anatomical limitations of the pig and/or complexity of the procedure and the preliminary stage of development of the accessory devices.
  
  
  BACKGROUND
  NOTES - Natural Orifice Translumenal Endoscopic Surgery; EUS - Endoscopic Ultrasound; EUSFNA - Endoscopic Ultrasound Fine Needle Aspiration.
authors: Research Center of Gastroenterology and Hepatology, University of Medicine and Pharmacy Craiova, Romania.
authors: A
authors: A
authors: Saftoiu
authors: P
authors: P
authors: Vilmann
authors: M S
authors: MS
authors: Bhutani
mesh_terms: D000818:Animals; D044963:Biopsy, Fine-Needle / Q000379:methods; D002763:Cholecystectomy / Q000379:methods*; D004195:Disease Models, Animal; D019160:Endosonography; D005240:Feasibility Studies; D005774:Gastrostomy / Q000379:methods*; D009055:Mouth; D057605:Natural Orifice Endoscopic Surgery / Q000379:methods*; D015203:Reproducibility of Results; D015607:Stents; D034421:Sus scrofa