title: Susceptibility to declarative memory interference is pronounced in primary insomnia.
abstract: Sleep has been shown to stabilize memory traces and to protect against competing interference in both the procedural and declarative memory domain. Here, we focused on an interference learning paradigm by testing patients with primary insomnia (N = 27) and healthy control subjects (N = 21). In two separate experimental nights with full polysomnography it was revealed that after morning interference procedural memory performance (using a finger tapping task) was not impaired in insomnia patients while declarative memory (word pair association) was decreased following interference. More specifically, we demonstrate robust associations of central sleep spindles (in N3) with motor memory susceptibility to interference as well as (cortically more widespread) fast spindle associations with declarative memory susceptibility. In general the results suggest that insufficient sleep quality does not necessarily show up in worse overnight consolidation in insomnia but may only become evident (in the declarative memory domain) when interference is imposed.
authors: Laboratory for Sleep, Cognition and Consciousness Research, Department of Psychology, University of Salzburg, Salzburg, Austria.
authors: Hermann
authors: H
authors: Griessenberger
authors: Dominik P J
authors: DP
authors: Heib
authors: Julia
authors: J
authors: Lechinger
authors: Nikolina
authors: N
authors: Luketina
authors: Marit
authors: M
authors: Petzka
authors: Tina
authors: T
authors: Moeckel
authors: Kerstin
authors: K
authors: Hoedlmoser
authors: Manuel
authors: M
authors: Schabus
mesh_terms: D000328:Adult; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory; D008875:Middle Aged; D007319:Sleep Initiation and Maintenance Disorders / Q000503:physiopathology / Q000523:psychology*