title: Staple line reinforcement during laparoscopic sleeve gastrectomy: does it affect clinical outcomes?
abstract: Although laparoscopic sleeve gastrectomy (LSG) is safe and efficacious treatment for morbid obesity, this procedure is associated with major staple line complications including leakage and bleeding. Staple-line reinforcement (SLR) either through suturing or buttressing with biological or synthetic material has been suggested as a method to prevent these complications. A Best Evidence Topic was constructed to address the question of whether SLR reduced these and other complications. MEDLINE, EMBASE and CINAHL searches up to October 2012 returned 97 unique results, of which nine (one meta-analysis, two randomised controlled trials (RCTs), six prospective cohort studies) provided the best evidence to answer this clinical question. We conclude that current evidence suggests that staple-line reinforcement reduces the incidence of leakage and postoperative complications than non-reinforcement but does not significantly reduce bleeding complications. However, we cannot as yet recommend staple-line reinforcement as the strength of the presented evidence is limited by the variable quality of the published studies. The full-length publication of several abstracts of randomised, controlled trials presented at various recent conferences is awaited. This may provide more data on the effect of staple-line reinforcement on other outcomes largely neglected by currently available studies.
authors: Department of Surgery, Queen Alexandra Hospital, Portsmouth Hospitals NHS Trust, UK.
authors: Michael
authors: M
authors: Glaysher
authors: Omar A
authors: OA
authors: Khan
authors: Nigel Tapiwa
authors: NT
authors: Mabvuure
authors: Andrew
authors: A
authors: Wan
authors: Marcus
authors: M
authors: Reddy
authors: Georgios
authors: G
authors: Vasilikostas
mesh_terms: D057868:Anastomotic Leak / Q000517:prevention & control; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D011183:Postoperative Complications / Q000517:prevention & control; D017792:Surgical Stapling; D016896:Treatment Outcome