title: Neuropeptides activate TRPV1 in rheumatoid arthritis fibroblast-like synoviocytes and foster IL-6 and IL-8 production.
authors: Riccardo
authors: R
authors: Terenzi
authors: Eloisa
authors: E
authors: Romano
authors: Mirko
authors: M
authors: Manetti
authors: Francesca
authors: F
authors: Peruzzi
authors: Francesca
authors: F
authors: Nacci
authors: Marco
authors: M
authors: Matucci-Cerinic
authors: Serena
authors: S
authors: Guiducci
mesh_terms: D001172:Arthritis, Rheumatoid / Q000503:physiopathology*; D015740:Calcitonin Gene-Related Peptide / Q000494:pharmacology / Q000502:physiology*; D002211:Capsaicin / Q000494:pharmacology; D016022:Case-Control Studies; D006801:Humans; D015850:Interleukin-6 / Q000378:metabolism*; D016209:Interleukin-8 / Q000187:drug effects / Q000378:metabolism*; D013373:Substance P / Q000494:pharmacology / Q000502:physiology*; D013583:Synovial Membrane / Q000166:cytology*; D050916:TRPV Cation Channels / Q000187:drug effects / Q000502:physiology*
chemical_list: C508606:CXCL8 protein, human; C508600:IL6 protein, human; D015850:Interleukin-6; D016209:Interleukin-8; D050916:TRPV Cation Channels; C494482:TRPV1 protein, human; D013373:Substance P; D015740:Calcitonin Gene-Related Peptide; D002211:Capsaicin
keywords: Fibroblasts; Inflammation; Rheumatoid Arthritis