title: Paraneoplastic subacute cutaneous lupus erythematosus: an underrecognized entity.
abstract: Subacute cutaneous lupus erythematosus (SCLE) is a form of cutaneous lupus erythematosus that most often presents as scaly, erythematous, papulosquamous, or annular papules and plaques in a photodistributed pattern. Subacute cutaneous lupus erythematosus is classically considered to be either idiopathic or drug induced. There have been few reports of SCLE arising in the setting of malignancy, raising the possibility that paraneoplastic SCLE may be a rare distinct subset of lupus. We report a case of SCLE arising as a paraneoplastic phenomenon in the setting of small cell lung cancer. Given the close temporal proximity of the detection of malignancy and the development of the rash in our patient, we believe this report presents a case of paraneoplastic SCLE. The presentation of new-onset idiopathic SCLE should prompt a careful review of systems and age-appropriate cancer screening, as SCLE may be a sign of an occult malignancy.
authors: Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, USA.
authors: Katherine G
authors: KG
authors: Evans
authors: Warren R
authors: WR
authors: Heymann
mesh_terms: D018288:Carcinoma, Small Cell / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008178:Lupus Erythematosus, Cutaneous / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D008297:Male; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology