title: Rapid eye movement sleep behavior disorder in a patient with brainstem lymphoma.
abstract: Rapid eye movement (REM) sleep behavior disorder (RBD) is common in patients with neurodegenerative diseases. RBD occurring in a patient with brainstem lymphoma has not yet been reported. A 30-year-old man had an eleven-month history of violent motor and vocal behavior during sleep. Brain magnetic resonance imaging disclosed hypointensity T1 and hyperintensity T2 signals in the pontomesencephalic junction and at the upper/mid pons level. A stereotactic biopsy demonstrated the presence of diffuse large B-cell lymphoma. On polysomnography, there was enhanced submental and limb electromyographic tone and increased muscular activity during REM sleep. Chemotherapy diminished the dream-enacting behaviors. This case provides evidence that treatment aimed at the primary disease can partially improve the frequency of RBD.
authors: Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, China.
authors: Chen
authors: C
authors: Jianhua
authors: Liu
authors: L
authors: Xiuqin
authors: Cui
authors: C
authors: Quancai
authors: Sun
authors: S
authors: Heyang
authors: Huang
authors: H
authors: Yan
mesh_terms: D000328:Adult; D020295:Brain Stem Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D020187:REM Sleep Behavior Disorder / Q000150:complications / Q000175:diagnosis* / Q000628:therapy