title: No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus.
abstract: It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses.
authors: Department of Biomedicine, Aarhus University, Aarhus C DK-8000, Denmark. maja.d.k@microbiology.au.dk
authors: M D
authors: MD
authors: Kaspersen
authors: M
authors: M
authors: Bungum
authors: J
authors: J
authors: Fedder
authors: J
authors: J
authors: Bonde
authors: P B
authors: PB
authors: Larsen
authors: H
authors: H
authors: J Ingerslev
authors: P
authors: P
authors: Höllsberg
mesh_terms: D053938:DNA Fragmentation; D006564:Herpesviridae / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D027383:Papillomaviridae / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D012661:Semen / Q000821:virology*