title: Recommendations for switching antipsychotics. A position statement of the Spanish Society of Psychiatry and the Spanish Society of Biological Psychiatry.
abstract: Switching antipsychotics is common in the clinical practice setting and is associated with potential clinically relevant complications. An expert group selected by Spanish Society of Psychiatry and the Spanish Society of Biological Psychiatry has reviewed the evidence provided by randomized clinical trials and other relevant information to reach consensus recommendations for switching antipsychotics. In this article, we will review all the information that has led to those recommendations and which includes: indications and contraindications for switching antipsychotics, pharmacological issues, switching strategies, switching antipsychotics due to efficacy problems, switching antispychotics due to tolerability issues (including extrapyramidal symptoms and tardive dyskinesia, weight gain, metabolic disorders, hyperprolactinemia, sexual dysfunction, persistent sedation, and QT prolongation), switching antypsychotics due to lack of treatment compliance, and switching antipsychotics in patients with bipolar disorders.
authors: Programa Esquizofrènia Clínic, Servei de Psiquiatria, Hospital Clínic, Universitat de Barcelona, Centro de Investigación Biomédica en Red de Salud Mental, Barcelona, España. bernardo@clinic.ub.es
authors: Miquel
authors: M
authors: Bernardo
authors: Eduard
authors: E
authors: Vieta
authors: Jerónimo
authors: J
authors: Saiz Ruiz
authors: Fernando
authors: F
authors: Rico-Villademoros
authors: Cecilio
authors: C
authors: Alamo
authors: Julio
authors: J
authors: Bobes