title: Increased 5-bromo-2’-deoxyuridine incorporation in various brain structures following passive avoidance training in mice.
abstract: We studied the effects of training on DNA synthesis intensity in mouse brain. Brain cells where DNA synthesis-associated processes took place under the influence of training were detected by immunohistochemical labeling of DNA molecules with synthetic thymine analogue 5-bromo-2’-deoxyuridine. The number of 5-bromo-2’-deoxyuridine-positive cell increased in various structures of the brain under the influence of training.
authors: Laboratory of Neurobiology of Memory, P. K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia. oivashkina@gmail.com
authors: O I
authors: OI
authors: Ivashkina
authors: M A
authors: MA
authors: Zots
authors: D V
authors: DV
authors: Bezriadnov
authors: K V
authors: KV
authors: Anokhin
mesh_terms: D000679:Amygdala / Q000378:metabolism; D000818:Animals; D001362:Avoidance Learning; D001921:Brain / Q000378:metabolism*; D001973:Bromodeoxyuridine / Q000008:administration & dosage / Q000378:metabolism*; D004247:DNA / Q000096:biosynthesis*; D007150:Immunohistochemistry; D007274:Injections, Intraperitoneal; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL
chemical_list: D004247:DNA; D001973:Bromodeoxyuridine