title: Particulated juvenile articular cartilage allograft transplantation for osteochondral lesions of the talus.
abstract: Osteochondral lesions of the talus can present a challenge to the orthopedic surgeon. Because of its avascular nature, articular cartilage has a poor capacity for self-repair and regeneration. A wide variety of strategies have been developed to restore the structure and function of injured cartilage. Surgical strategies range from repair of cartilage through the formation of fibrocartilage to a variety of restorative procedures, including tissue-engineering-based strategies. A novel treatment option involves the implantation of particulated articular cartilage obtained from a juvenile allograft donor, the DeNovo NT graft. This article reviews the DeNovo NT graft, its usage, and surgical technique.
authors: Institute for Foot & Ankle Reconstruction, Mercy Medical Center, 301 St. Paul Place, Baltimore, MD 21202, USA. rcerrato@mdmercy.com
authors: Rebecca
authors: R
authors: Cerrato
mesh_terms: D016025:Bone Transplantation / Q000379:methods*; D002356:Cartilage / Q000601:surgery* / Q000637:transplantation; D002358:Cartilage, Articular / Q000473:pathology* / Q000601:surgery; D006801:Humans; D019637:Orthopedic Procedures / Q000379:methods*; D010007:Osteochondritis / Q000601:surgery*; D013628:Talus / Q000601:surgery* / Q000637:transplantation; D023822:Tissue Engineering / Q000379:methods*; D014184:Transplantation, Homologous