title: Remarkable effect of CF3CH2OH for the halogen induced oxidative rearrangement reaction of aminals leading to 3,4-dihydroquinazolines.
abstract: CF3CH2OH was found to be a useful solvent for the oxidative rearrangement reactions of aminals promoted by N-chlorosuccinimide, which proceed via the intermediacy of in situ formed chloro-aminals and that produce 3,4-dihydroquinazolines.
authors: Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565-0871, Japan.
authors: Kenichi
authors: K
authors: Murai
authors: Masato
authors: M
authors: Shimura
authors: Ryu
authors: R
authors: Nagao
authors: Daisuke
authors: D
authors: Endo
authors: Hiromichi
authors: H
authors: Fujioka
mesh_terms: D000080:Acetals / Q000737:chemistry; D000588:Amines / Q000737:chemistry; D006219:Halogens / Q000737:chemistry*; D010084:Oxidation-Reduction; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry; D012997:Solvents; D013388:Succinimides / Q000737:chemistry*; D014270:Trifluoroethanol / Q000737:chemistry*
chemical_list: D000080:Acetals; D000588:Amines; D006219:Halogens; D011799:Quinazolines; D012997:Solvents; D013388:Succinimides; C015752:N-chlorosuccinimide; D014270:Trifluoroethanol