title: Multidisciplinary management of patients with localized bladder cancer.
abstract: Multidisciplinary approach to muscle-invasive bladder cancer is imperative to achieve optimal long-term cancer control. Radical cystectomy, pelvic lymph node dissection, and urinary diversion have been the mainstay of therapy for decades. Laparoscopic and robotic-assisted surgical techniques are becoming increasingly prevalent, and have shown short-term benefits in terms of blood loss, less pain, and smaller incisions. Neoadjuvant chemotherapy plus surgery results in absolute survival advantage and this approach is encouraged in appropriate patients. A similar survival advantage with the use of adjuvant chemotherapy has yet to be convincingly demonstrated. Bladder-preservation protocols involving a visibly complete transurethral resection followed by chemoradiation may be a feasible option for select patients.
authors: Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
authors: Kiranpreet K
authors: KK
authors: Khurana
authors: Jorge A
authors: JA
authors: Garcia
authors: Rahul D
authors: RD
authors: Tendulkar
authors: Andrew J
authors: AJ
authors: Stephenson
mesh_terms: D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D006801:Humans; D001749:Urinary Bladder Neoplasms / Q000628:therapy*