title: Beating heart surgery with pulmonary perfusion and ventilation during cardiopulmonary bypass: target organs' perfusion without plegia.
abstract: Myocardial and pulmonary ischemia during cardiopulmonary bypass (CPB) is associated with cardiac and pulmonary dysfunction that may result in poor outcomes after cardiac surgery. Beating heart surgery and continuous pulmonary perfusion and ventilation represent emerging strategies targeting the cardiopulmonary bypass-induced ischemia and ischemia-reperfusion injury in susceptible organs--heart and lungs.
authors: Division of Cardiothoracic Surgery, Jackson Memorial Hospital, University of Miami Miller School of Medicine, Miami, Florida, USA.
authors: Francisco Igor B
authors: FI
authors: Macedo
authors: Edward
authors: E
authors: Gologorsky
authors: Ana Claudia B A
authors: AC
authors: Costa
authors: Si M
authors: SM
authors: Pham
authors: Tomas A
authors: TA
authors: Salerno
mesh_terms: D006348:Cardiac Surgical Procedures / Q000009:adverse effects; D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D006801:Humans; D055370:Lung Injury / Q000209:etiology / Q000517:prevention & control*; D015428:Myocardial Reperfusion Injury / Q000209:etiology / Q000517:prevention & control*; D010477:Perfusion / Q000009:adverse effects / Q000379:methods*; D011652:Pulmonary Circulation; D015427:Reperfusion Injury / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control*; D012121:Respiration, Artificial; D016896:Treatment Outcome