title: Copper-catalyzed aromatic C-H bond halogenation with lithium halides under aerobic conditions.
abstract: A concise and practical Cu-catalyzed protocol for the preparation of chloro- and bromoarenes via C-H bond activation has been developed. The advantages of this strategy are the employment of cheap Cu(NO3)2·3H2O, LiX and O2, and its compatibility with both electron-donating and electron-withdrawing substituents on aryl rings.
authors: Department of Chemistry, College of Life and Environment Sciences, Shanghai Normal University, 100 Guilin Road, Shanghai, 200234, China.
authors: Song
authors: S
authors: Mo
authors: Yamin
authors: Y
authors: Zhu
authors: Zengming
authors: Z
authors: Shen
mesh_terms: D002384:Catalysis; D003300:Copper / Q000737:chemistry; D054879:Halogenation; D006219:Halogens / Q000737:chemistry*; D006842:Hydrocarbons, Brominated / Q000138:chemical synthesis* / Q000737:chemistry; D006843:Hydrocarbons, Chlorinated / Q000138:chemical synthesis* / Q000737:chemistry; D008094:Lithium / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*
chemical_list: D006219:Halogens; D006842:Hydrocarbons, Brominated; D006843:Hydrocarbons, Chlorinated; D009942:Organometallic Compounds; D003300:Copper; D008094:Lithium; D010100:Oxygen