title: Schistosomiasis in African infants and preschool children: let them now be treated!
abstract: The occurrence of schistosomiasis within African infants and preschool children has been much better documented in recent years, revealing an important burden of disease previously overlooked. Despite mounting evidence showing that treatment with praziquantel is safe, beneficial, and could be delivered within ongoing public health interventions, young children still do not have satisfactory access to this drug, and a significant treatment gap exists. Progress towards resolution of this unfortunate health inequity is highlighted, including the development of an appropriate paediatric praziquantel formulation, and present blocks are identified on securing this issue within the international health agenda.
authors: Parasitology Department, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK. jrstoth@liv.ac.uk
authors: J Russell
authors: JR
authors: Stothard
authors: José C
authors: JC
authors: Sousa-Figueiredo
authors: Martha
authors: M
authors: Betson
authors: Amaya
authors: A
authors: Bustinduy
authors: Jutta
authors: J
authors: Reinhard-Rupp
mesh_terms: D000349:Africa / Q000453:epidemiology; D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D011223:Praziquantel / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D015995:Prevalence; D011634:Public Health; D012552:Schistosomiasis / Q000188:drug therapy* / Q000453:epidemiology
chemical_list: D000871:Anthelmintics; D011223:Praziquantel