title: Antiretroviral treatment adherence in childhood and adolescence: multidisciplinary team as an associated factor in Brazil.
abstract: Our aim was to analyze factors associated with non-adherence to antiretroviral (ARV) treatment among children and adolescents. A cross-sectional study was carried out involving non-institutionalized children and adolescents between 2 and 20 years of age, addressing non-adherence to ARV treatment, which was defined as taking ≤89% of the medications on the day of the interview and the three previous days. The investigation into the association between non-compliance and the variables of interest was performed using unconditional logistic regression. The independent factors associated with non-adherence were forgetfulness (OR = 3.22; 95%CI = 1.75-5.92), difficulties coping with treatment (OR = 2.65; 95%CI = 1.03-6.79), and living with grandparents (OR = 2.28; 95%CI = 1.08-4.83), whereas a protective effect was found with participation in multidisciplinary activities (OR = 0.49; 95%CI = 0.25-0.96), i.e., this factor indicates that the exposure to the variable is beneficial, promoting adherence. We concluded that forgetting to take the medications and reporting having difficulty coping with ARV treatment are potentially modifiable factors through educational and programmatic actions. Residing with one's grandparents may strongly impact adherence to ARV treatment, indicating the need for the systematic support of these family members. Participation in multidisciplinary activities should be stimulated at health-care services.
authors: a Department of Biological Sciences , Federal University of São Paulo , São Paulo , Brazil.
authors: Marcia Terezinha Lonardoni
authors: MT
authors: Crozatti
authors: Ivan
authors: I
authors: França-Junior
authors: Rosangela
authors: R
authors: Rodrigues
authors: Maria do Socorro
authors: Mdo S
authors: Carneiro Ferrão
authors: Luis Fernando M
authors: LF
authors: Brigido
authors: Marinella
authors: M
authors: Della Negra
authors: Alexandre Ely
authors: AE
authors: Campéas
authors: Miriam Elia
authors: ME
authors: Castilho Raymundo
authors: Silvia Regina
authors: SR
authors: Marques
authors: Eliseu Alves
authors: EA
authors: Waldman
mesh_terms: D000293:Adolescent; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D010348:Patient Care Team; D010349:Patient Compliance; D057566:Self Report; D012959:Socioeconomic Factors; D055815:Young Adult; D016903:Drug Monitoring
chemical_list: D019380:Anti-HIV Agents