title: Oculopharyngeal muscular dystrophy as a cause of progression of weakness in antibody positive myasthenia gravis.
abstract: Many neuromuscular conditions cause bulbar and limb weakness, and when several conditions coexist they present additional diagnostic challenges. Here we describe a case of a 45-year-old woman with antibody positive myasthenia gravis since age 16, who then develops treatment-resistant weakness due to genetically proven oculopharyngeal muscular dystrophy. We conclude that the development of treatment-resistant weakness in myasthenia gravis should spur further work up for other neuromuscular disorders including oculopharyngeal muscular dystrophy.
authors: Department of Neurology, University of California, Davis, 4860 Y St. Suite 3700, Sacramento, CA 95817, USA. bjorn.oskarsson@ucdmc.ucdavis.edu
authors: Björn
authors: B
authors: Oskarsson
authors: Steven P
authors: SP
authors: Ringel
mesh_terms: D018450:Disease Progression; D005260:Female; D006801:Humans; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology*; D039141:Muscular Dystrophy, Oculopharyngeal / Q000150:complications*; D009157:Myasthenia Gravis / Q000150:complications* / Q000276:immunology; D011950:Receptors, Cholinergic / Q000276:immunology
chemical_list: D011950:Receptors, Cholinergic