title: Malignant lesions on mammography: accuracy of two different computer-aided detection systems.
abstract: We retrospectively compared the accuracy of two computer-aided detection (CAD) systems for the detection of malignant breast lesions on full-field digital mammograms. Mammograms of 326 patients were analyzed (117 patients with breast cancer, 209 negative cases), and each set of cases was read by two CAD systems (Second Look versus AccuDetect Galileo). True-positive fractions per image and case for soft densities, microcalcifications, and total cancers were assessed. Study results showed better overall performance of AccuDetect Galileo (when compared to Second Look) in detecting masses, microcalcifications, and all cancer types, especially in extremely dense breast parenchyma.
authors: Maastricht University Medical Center, GROW School for Oncology and Developmental Biology, Department of Radiology, Maastricht, The Netherlands. marc.lobbes@mumc.nl
authors: Marc
authors: M
authors: Lobbes
authors: Marjolein
authors: M
authors: Smidt
authors: Kristien
authors: K
authors: Keymeulen
authors: Rossano
authors: R
authors: Girometti
authors: Chiara
authors: C
authors: Zuiani
authors: Regina
authors: R
authors: Beets-Tan
authors: Joachim
authors: J
authors: Wildberger
authors: Carla
authors: C
authors: Boetes
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D011856:Radiographic Image Enhancement / Q000379:methods*; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014584:User-Computer Interface