title: Needleless closed system does not reduce central venous catheter-related bloodstream infection: a retrospective study.
abstract: The needleless closed system (NCS) has been disseminated in several clinical fields to prevent central venous catheter-related bloodstream infection (CVC-RBSI), in place of the conventional Luer cap system (LCS). The purpose of this study is to examine whether NCS is really superior to conventional LCS for prevention of CVC-RBSI. Between May 2002 and December 2008, 1767 patients received CVC in our department. The time interval from insertion to development of CVC-RBSI was compared retrospectively between selected patients who were treated using the conventional LCS (group 1, n = 89, before June 2006) and the NCS (group 2, n = 406, June 2006 and after). Kaplan-Meier analysis revealed no significant difference in the time interval from insertion to development of CVC-RBSI between the two groups. NCS does not reduce CVC-RBSI in adult colorectal cancer patients who undergo CVC insertion.
authors: Department of Gastroenterological Surgery, Dokkyo Medical University, Tochigi, Japan.
authors: Mitsuru
authors: M
authors: Ishizuka
authors: Hitoshi
authors: H
authors: Nagata
authors: Kazutoshi
authors: K
authors: Takagi
authors: Keiichi
authors: K
authors: Kubota
mesh_terms: D000368:Aged; D055499:Catheter-Related Infections / Q000517:prevention & control*; D002405:Catheterization, Central Venous / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D062905:Central Venous Catheters / Q000009:adverse effects*; D003428:Cross Infection / Q000517:prevention & control*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome