title: [Megacystis-microcolon intestinal hypoperistalsis syndrome (MMIHS) as a rare differential diagnosis of foetal megacystis on ultrasonography].
abstract: BACKGROUND
  Foetal megacystis (incidence 1:1 500) occurring in the first trimester may already be a sign of congenital malformation. Often, urethral valves are causally responsible in male foetuses far more frequently than urethral atresia. As a further differential diagnosis, the "prune-belly syndrome" needs to be distinguished. Far more difficult to classify prenatally is the rare MMIHS which, in contrast to the diagnosis of urethral valves, is associated with an unfavourable prognosis.
  
  
  METHODS
  This is a report on a 28-year-old IG/0P, whose foetus of 26+4 gestational weeks was found on ultrasonography for the first time to have a megacystis of 48 mm diameter and bilateral hydronephrosis. The female foetus was surrounded by a normal amount of amniotic fluid which, during the further course of the pregnancy, developed into polyhydramnios. The serial puncture of the urinary bladder showed a normal karyotype and no impairment of the renal concentrating capacity or of protein loss. By reason of an immense enlargement of the abdomen due to the 100 mm large urinary bladder, a Caesarean section was conducted at 36+0 gestational weeks. A catheter could be inserted into the urinary bladder postpartum easily. However, nourishment was not possible and after radiological examination, MMIHS was diagnosed.
  
  
  CONCLUSIONS
  In the case of a foetal megacystis detected by ultrasonography, especially associated with polyhydramnios and female gender, the rare MMIHS, which is infaust, should be taken into consideration.
authors: Klinik für Gyn. u. Geburtsmedizin, Vivantes Klinikum im Friedrichshain, Berlin. Lars.Hellmeyer@vivantes.de
authors: L
authors: L
authors: Hellmeyer
authors: K
authors: K
authors: Herz
authors: S
authors: S
authors: Maslovar
authors: B
authors: B
authors: Liedke
authors: R
authors: R
authors: Laux
authors: B J
authors: BJ
authors: Hackelöer
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging*; D003106:Colon / Q000002:abnormalities / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D004386:Duodenum / Q000002:abnormalities / Q000000981:diagnostic imaging; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging*; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000000981:diagnostic imaging*; D008297:Male; D011247:Pregnancy; D016216:Ultrasonography, Prenatal / Q000379:methods*; D001743:Urinary Bladder / Q000002:abnormalities / Q000000981:diagnostic imaging