title: Metabolic fingerprinting of Angelica sinensis during growth using UPLC-TOFMS and chemometrics data analysis.
abstract: BACKGROUND
  The radix of Angelica sinensis is widely used as a medicinal herbal and metabolomics research of this plant during growth is necessary.
  
  
  RESULTS
  Principal component analysis of the UPLC-QTOFMS data showed that these 27 samples could be separated into 4 different groups. The chemical markers accounting for these separations were identified from the PCA loadings plot. These markers were further verified by accurate mass tandem mass and retention times of available reference standards. The study has shown that accumulation of secondary metabolites of Angelica sinensis is closely related to the growth periods.
  
  
  CONCLUSIONS
  The UPLC-QTOFMS based metabolomics approach has great potential for analysis of the alterations of secondary metabolites of Angelica sinensis during growth.
authors: Key Laboratory of Dunhuang Medicine and Transformation, Ministry of Education, Research Institute of Angelica sinensis, Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China. cnwyl1166@hotmail.com.
authors: Yiyun
authors: Y
authors: Qian
authors: Yali
authors: Y
authors: Wang
authors: Rina
authors: R
authors: Sa
authors: Hui
authors: H
authors: Yan
authors: Xinbo
authors: X
authors: Pan
authors: Yingwen
authors: Y
authors: Yang
authors: Yujing
authors: Y
authors: Sun