title: Caspr2 antibodies in limbic encephalitis with cerebellar ataxia, dyskinesias and myoclonus.
abstract: Here we report on a case of contactin-associated protein-2 (Caspr2) antibody positive but voltage gated potassium channel (VGKC) antibody negative limbic encephalitis associated with cerebellar ataxia, myoclonus and dyskinesias with favorable response to immunotherapy. This case underlines the importance of Caspr2-specific antibody testing and demonstrates that Caspr2 antibodies are associated with a broader clinical spectrum than hitherto described.
authors: Division of Molecular Neuroimmunology, Department of Neurology, University Hospital, Heidelberg, Germany.
authors: Bettina
authors: B
authors: Balint
authors: Jens Uwe
authors: JU
authors: Regula
authors: Sven
authors: S
authors: Jarius
authors: Brigitte
authors: B
authors: Wildemann
mesh_terms: D001323:Autoantibodies / Q000097:blood*; D002524:Cerebellar Ataxia / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D020820:Dyskinesias / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D005260:Female; D006801:Humans; D020363:Limbic Encephalitis / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D008565:Membrane Proteins / Q000097:blood*; D008875:Middle Aged; D009207:Myoclonus / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D009419:Nerve Tissue Proteins / Q000097:blood*
chemical_list: D001323:Autoantibodies; C403049:CNTNAP2 protein, human; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins