title: Distinguishing subtypes in primary progressive aphasia: application of the Sydney language battery.
abstract: OBJECTIVE
  Primary progressive aphasia (PPA) comprises three main subtypes, varying in clinical features, patterns of brain atrophy, and underlying pathology. Differentiation of these variants is important for treatment and planning; however, simple, effective cognitive tests to aid diagnosis are lacking. This study introduces a new language battery - the SYDBAT (Sydney Language Battery) - to assist clinicians.
  
  
  METHODS
  Fifty-seven PPA patients and 54 age- and education-matched healthy controls were compared on naming, repetition, word comprehension, and semantic association subtests.
  
  
  RESULTS
  Significant group differences were found for all tasks, reflecting different language profiles for each group. Using discriminative function analysis, 80% of PPA cases were correctly classified from three SYDBAT scores, from which a simple diagnostic algorithm was defined.
  
  
  CONCLUSIONS
  The SYDBAT is a fast and simple tool which provides a valuable adjunct to clinicians diagnosing PPA.
authors: Neuroscience Research Australia, University of New South Wales, Sydney, N.S.W., Australia.
authors: Sharon
authors: S
authors: Savage
authors: Sharpley
authors: S
authors: Hsieh
authors: Felicity
authors: F
authors: Leslie
authors: David
authors: D
authors: Foxe
authors: Olivier
authors: O
authors: Piguet
authors: John R
authors: JR
authors: Hodges
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D018888:Aphasia, Primary Progressive / Q000145:classification / Q000175:diagnosis*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D015203:Reproducibility of Results