title: Self-assembled oligo(phenylene ethynylene)s/graphene nanocomposite with improved electrochemical performances for dopamine determination.
abstract: In this work, a novel 1,4-bis (4- aminophenylethynyl)benzene (OPE-NH2, a symmetric linear conjugated oligo(phenylene ethynylene)s derive) and chemically-reduced graphene oxide (rGO) nanocomposite (OPE-NH2/rGO) was synthesized by a simple self-assembly method. The OPE-NH2/rGO nanocomposite was stable and water soluble. The formation of OPE-NH2/rGO nanocomposite was ascribed to the π-π stacking interaction between the conjugated structure of OPE-NH2 and rGO as well as the electrostatic force between the amino group of OPE-NH2 and the carboxyl group on rGO, which was characterized by FT-IR, UV-vis spectra and fluorescence spectra. The OPE-NH2/rGO nanocomposite exhibited significantly improved electrocatalytic activity to the oxidization of dopamine (DA) than that of rGO or OPE-NH2. The electrochemical performances of OPE-NH2/rGO were dependent on the OPE-NH2 contents, and OPE-NH2 content of 5wt% exhibited the highest activity. Compared with that of rGO, the nanocomposite presented superior high sensitivity with detection limit of 5nM, excellent selectivity, wide linear range (0.01-60μM) and good stability on the determination of DA. The practical application of the developed OPE-NH2/rGO nanocomposite modified electrode was successfully demonstrated for DA determination in human serum samples.
authors: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China.
authors: Jianhui
authors: J
authors: Deng
authors: Meilin
authors: M
authors: Liu
authors: Fanbo
authors: F
authors: Lin
authors: Youyu
authors: Y
authors: Zhang
authors: Yang
authors: Y
authors: Liu
authors: Shouzhuo
authors: S
authors: Yao
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D004298:Dopamine / Q000097:blood*; D055664:Electrochemical Techniques / Q000295:instrumentation; D004987:Ethers / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D053761:Nanocomposites / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*
chemical_list: D000480:Alkynes; D004987:Ethers; D010087:Oxides; C436384:phenyleneethynylene; D006108:Graphite; D004298:Dopamine