title: Clinicoepidemiological study of skin manifestations in patients of chronic renal failure on hemodialysis.
abstract: BACKGROUND
  Chronic renal failure (CRF) is associated with a variety of cutaneous manifestations as a result of underlying etiology as well as the various treatment modalities.
  
  
  OBJECTIVE
  To evaluate the prevalence of various dermatoses in patients with CRF on hemodialysis and to study the effect of hemodialysis on the intensity of pruritus.
  
  
  METHODS
  A total of 35 patients of CRF on hemodialysis having at least one cutaneous manifestation were included in the study.
  
  
  RESULTS
  Twenty-four (68.71%) cases in our study belonged to the age group of 50-69 years, out of which 16 cases were in the sixth decade. Xerosis and pruritus occurred in 80% and 65.71% of cases, respectively. Other common findings included pallor (68.57%), dyspigmentation (34.29%), cutaneous infections (34.39%), acquired perforating dermatosis (17.4%), and nail changes (60%). Hemodialysis failed to improve pruritus in 17 (73.9%) of our patients. Twenty-six patients (74.28%) suffered from hypertension, 13 of them also were known cases of type II diabetes mellitus. Five patients suffered exclusively from type II diabetes mellitus.
  
  
  CONCLUSIONS
  In our small study, xerosis was the commonest finding and pruritus, the commonest symptom. The intensity of pruritus was largely unaffected by hemodialysis.
authors: Department of Dermatology, Dr. D. Y. Patil Medical College and Hospital, Pimpri, Pune, India.
authors: Supriya P
authors: SP
authors: Deshmukh
authors: Yugal K
authors: YK
authors: Sharma
authors: Kedarnath
authors: K
authors: Dash
authors: Nitin C
authors: NC
authors: Chaudhari
authors: Kirti S
authors: KS
authors: Deo
keywords: Acquired perforating disorder; chronic renal failure; hemodialysis; pruritus; xerosis