title: Midchildhood acne associated with inhaled corticosteroids: report of two cases and review of the literature.
abstract: Midchildhood acne has been attributed to a number of causes in the literature, including adrenocortical tumor, hyperandrogenemia due to hypothalamic dysfunction, and contact with greasy topical skin care products. There are only a few case reports of inhaled steroids causing acneiform eruptions, all of which occurred in adults and with symptoms suggesting that the acne resulted from systemic absorption. We present two cases of comedonal and inflammatory midchildhood acne temporally associated with the use of inhaled corticosteroids administered through face masks, implicating a causative relationship between topical steroid exposure and midchildhood acne that does not necessitate systemic absorption.
authors: Yale University School of Medicine, New Haven, Connecticut.
authors: Kristina J
authors: KJ
authors: Liu
authors: Richard J
authors: RJ
authors: Antaya
mesh_terms: D017486:Acneiform Eruptions / Q000139:chemically induced* / Q000188:drug therapy; D000068816:Adapalene; D000280:Administration, Inhalation; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects*; D000730:Androstadienes / Q000008:administration & dosage / Q000009:adverse effects*; D001993:Bronchodilator Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002675:Child, Preschool; D005145:Face; D005260:Female; D000068298:Fluticasone; D006801:Humans; D008297:Male; D009281:Naphthalenes / Q000627:therapeutic use; D009330:Nebulizers and Vaporizers
chemical_list: D000305:Adrenal Cortex Hormones; D000730:Androstadienes; D001993:Bronchodilator Agents; D009281:Naphthalenes; D000068816:Adapalene; D000068298:Fluticasone