title: Adipokines and vascular health in treated HIV infection: an obesity paradox?
abstract: We examined the relationship between plasma adipokine concentrations and ultrasound measures of vascular health in 100 HIV-infected adults on antiretroviral therapy. Leptin was positively correlated with flow-mediated dilation of the brachial artery and negatively with carotid intima-media thickness. These relationships were independent of traditional risk factors and trunk fat in women but not men. Neither adiponectin nor resistin was associated with either measure of vascular health.
authors: University Hospitals Case Medical Center.
authors: Chris T
authors: CT
authors: Longenecker
authors: Whitney
authors: W
authors: Dunn
authors: Ying
authors: Y
authors: Jiang
authors: Sara M
authors: SM
authors: Debanne
authors: Grace A
authors: GA
authors: McComsey
mesh_terms: D015502:Absorptiometry, Photon; D054392:Adipokines / Q000097:blood*; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D015992:Body Mass Index; D001916:Brachial Artery / Q000000981:diagnostic imaging; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D015658:HIV Infections / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D020738:Leptin / Q000097:blood; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood*; D052243:Resistin / Q000097:blood; D012307:Risk Factors; D014463:Ultrasonography
chemical_list: D054392:Adipokines; D019380:Anti-HIV Agents; D020738:Leptin; D052243:Resistin