title: New Delhi metallo-beta-lactamase: a weapon for the newly emerging drug-resistant bacteria.
abstract: The world has seen the emergence of many micro-organisms in the recent past, which can curb human population with their newly built genetic make-up. The latest addition to this list of panic creating organisms is, bacteria encoding the gene for New Delhi metallo-beta-lactamase (NDM-1). NDM-1 is an enzyme that can hydrolyze and inactivate carbapenems, which are used as a last resort for the treatment of multi-resistant bacterial infections. Names of these bacteria were not found in the medical literature before December 2009, because of which it can take the credit of becoming a powerful emerging bacteria, which are difficult to treat. Besides Escherichia coli and Klebsiella pneumoniae, other bacterial strains have also expressed the gene for NDM-1, which are detected in many countries.
authors: Department of Microbiology, M.K.C.G Medical College, Brahmapur, Odisha, India. padhisanghamitra@yahoo.com
authors: Sanghamitra
authors: S
authors: Padhi
mesh_terms: D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology*; D024901:Drug Resistance, Multiple, Bacterial; D004755:Enterobacteriaceae / Q000187:drug effects* / Q000201:enzymology*; D006801:Humans; D007194:India; D001618:beta-Lactamases / Q000378:metabolism*
chemical_list: D001618:beta-Lactamases; C552864:beta-lactamase NDM-1