title: Catalytic enantioselective decarboxylative cyanoalkylation of imines by using palladium pincer complexes with C2-symmetric chiral bis(imidazoline)s.
abstract: Manifold products: The enantioselective decarboxylative Mannich-type reaction of cyanoacetic acid with N-(2-pyridinesulfonyl)imines catalyzed by chiral 1,3-bis(imidazolin-2-yl)benzene (Phebim)-Pd(II) complexes afforded products with good enantioselectivity (see scheme). The reaction was applied to a wide range of imines with good yield and enantioselectivity. The obtained products can be converted into various compounds without the loss of enantiopurity.
authors: Department of Frontier Materials, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya 466-8555, Japan.
authors: Kengo
authors: K
authors: Hyodo
authors: Masaru
authors: M
authors: Kondo
authors: Yasuhiro
authors: Y
authors: Funahashi
authors: Shuichi
authors: S
authors: Nakamura