title: The factors influencing urinary arsenic excretion and metabolism of workers in steel and iron smelting foundry.
abstract: In order to evaluate the degree of arsenic (As) exposure and the factors influencing urinary As excretion and metabolism, 192 workers from a steel and iron smelting plant, with different type of work in production such as roller, steel smelting, iron smelting and metallic charge preparation, were recruited. Information about characteristics of each subject was obtained by questionnaire and inorganic As (iAs), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA) in urine were determined. The results showed that steel smelters had significantly higher concentrations of DMA and total As (TAs) than rollers and metallic charge preparation workers, and iron and steel smelters had a higher value of primary methylation index and lower proportion of the iAs (iAs%) than rollers and metallic charge preparation workers. In steel smelters, urinary As level exceeded the biological exposure index (BEI) limit for urinary As of 35 μg/l by 65.52%, and higher than metallic charge preparation workers (35.14%). The individuals consumed seafood in recent 3 days had a higher TAs than the individuals without seafood consumption. Multivariate logistic regression analysis showed that different jobs, taken Chinese medicine of bezoar and seafood consumption in recent 3 days were significantly associated with urinary TAs exceeded BEI limit value 35 μg/l. Our results suggest that workers in steel and iron smelting plant had a lower level of As exposure, and seafood consumption and taking Chinese medicine of bezoar also could increase the risk of urinary TAs exceeded BEI limit value.
authors: Department of Environmental and Occupational Health, Liaoning Provincial Key Laboratory of Arsenic Biological Effect and Poisoning, School of Public Health, China Medical University, District of Heping, North Er Road, No. 92, Shenyang City, 110001, China.
authors: Xi
authors: X
authors: Shuhua
authors: Department of Environmental and Occupational Health, Liaoning Provincial Key Laboratory of Arsenic Biological Effect and Poisoning, School of Public Health, China Medical University, District of Heping, North Er Road, No. 92, Shenyang City, 110001, China.
authors: Sun
authors: S
authors: Qingshan
authors: Department of Environmental and Occupational Health, Liaoning Provincial Key Laboratory of Arsenic Biological Effect and Poisoning, School of Public Health, China Medical University, District of Heping, North Er Road, No. 92, Shenyang City, 110001, China.
authors: Wang
authors: W
authors: Fei
authors: Department of Environmental and Occupational Health, Liaoning Provincial Key Laboratory of Arsenic Biological Effect and Poisoning, School of Public Health, China Medical University, District of Heping, North Er Road, No. 92, Shenyang City, 110001, China.
authors: Liu
authors: L
authors: Shengnan
authors: Department of Environmental and Occupational Health, Liaoning Provincial Key Laboratory of Arsenic Biological Effect and Poisoning, School of Public Health, China Medical University, District of Heping, North Er Road, No. 92, Shenyang City, 110001, China.
authors: Yan
authors: Y
authors: Ling
authors: Department of Environmental and Occupational Health, Liaoning Provincial Key Laboratory of Arsenic Biological Effect and Poisoning, School of Public Health, China Medical University, District of Heping, North Er Road, No. 92, Shenyang City, 110001, China.
authors: Zhang
authors: Z
authors: Lin
authors: Department of Environmental and Occupational Health, Liaoning Provincial Key Laboratory of Arsenic Biological Effect and Poisoning, School of Public Health, China Medical University, District of Heping, North Er Road, No. 92, Shenyang City, 110001, China.
authors: Song
authors: S
authors: Yingli
authors: Department of Environmental and Occupational Health, Liaoning Provincial Key Laboratory of Arsenic Biological Effect and Poisoning, School of Public Health, China Medical University, District of Heping, North Er Road, No. 92, Shenyang City, 110001, China.
authors: Yan
authors: Y
authors: Nan
authors: Department of Environmental and Occupational Health, Liaoning Provincial Key Laboratory of Arsenic Biological Effect and Poisoning, School of Public Health, China Medical University, District of Heping, North Er Road, No. 92, Shenyang City, 110001, China.
authors: Sun
authors: S
authors: Guifan
mesh_terms: D000328:Adult; D001151:Arsenic / Q000378:metabolism* / Q000652:urine; D001152:Arsenicals / Q000652:urine; D002101:Cacodylic Acid / Q000652:urine; D002681:China; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D006801:Humans; D007501:Iron; D016015:Logistic Models; D008452:Maximum Allowable Concentration; D008669:Metallurgy; D016273:Occupational Exposure / Q000032:analysis*; D017747:Seafood; D013232:Steel; D011795:Surveys and Questionnaires
chemical_list: D001152:Arsenicals; D004365:Drugs, Chinese Herbal; D013232:Steel; D002101:Cacodylic Acid; D007501:Iron; C020300:monomethylarsonic acid; D001151:Arsenic