title: Feasibility and outcomes of endovascular embolization of cerebral arteriovenous malformations at a low-volume centre.
abstract: OBJECTIVE
  Herein, we report our initial experience with the endovascular management of cerebral arteriovenous malformations (AVMs) using the liquid embolic agent Onyx and n-butyl cyanoacrylate for AVM embolization.
  
  
  METHODS
  We reviewed data from 15 patients with brain AVMs, who were observed at our endovascular facility from January 2008 to July 2011. All cases were embolized with Onyx and/or n-butyl cyanoacrylate. There were 8 women and 7 men with a mean age of 27.2 years (range 17-43 years). The clinical presentations included intracerebral haemorrhage (n = 7), seizures (n = 4), headache (n = 2), and focal neurological deficits (n = 2); according to the Spetzler-Martin classification (Spetzler R and Martin N (1986) J NeurosurgV65 446-83), 8 AVMs were grades I-II, 5 were grade III, and 2 were grades IV-V.
  
  
  RESULTS
  A total of 31 embolization procedures were performed in 15 patients, and 44 feeding pedicles were embolized, ranging from 1 to 5 per patient, with an average size reduction of 70% (median 75%, range 40-100%). Total obliteration was achieved for 3 AVMs (20%) (2 patients had single feeders and 1 patient had double feeders), and a partial embolization was achieved in 12 patients (80%). The procedure was related to a permanent disabling morbidity in one patient (6.6%), and no mortalities occurred.
  
  
  CONCLUSIONS
  The outcome of (AVM) embolization in our centre is comparable to the reported outcome in other larger-volume centres. The feasibility and safety of AVM embolization in our low-volume centre are similar to the outcomes reported at high-volume centre.
authors: Department of Neurology, Al-Azhar University, Cairo, Egypt.
authors: K
authors: K
authors: Sobh
authors: A
authors: A
authors: Hegazy
keywords: Onyx; cerebral AVMs; endovascular treatment; low-volume centres; n-BCA