title: The U.S. military's Neisseria gonorrhoeae resistance surveillance initiatives in selected populations of five countries.
abstract: Multi-drug resistant Neisseria gonorrhoeae (GC) threatens the successful treatment of gonorrhea. This report presents preliminary findings with regard to the prevalence of laboratory-confirmed GC and the extent of drug-resistance among sample populations in five countries. Between October 2010 and January 2013, 1,694 subjects (54% male; 45% female; 1% unknown) were enrolled and screened for the presence of laboratory-confirmed GC in the United States, Djibouti, Ghana, Kenya, and Peru. Overall, 108 (6%) of enrolled subjects tested positive for GC. Antimicrobial susceptibility testing results were available for 66 GC isolates. Resistance to at least three antibiotics was observed at each overseas site. All isolates tested in Ghana (n=6) were resistant to ciprofloxacin, penicillin, and tetracycline. In Djibouti, preliminary results suggested resistance to penicillin, tetracycline, ciprofloxacin, cefepime, and ceftriaxone. The small sample size and missing data prevent comparative analysis and limit the generalizability of these preliminary findings.
authors: Armed Forces Health Surveillance Center, Silver Spring, Maryland, USA.
authors: Alice Y
authors: AY
authors: Tsai
authors: Erica
authors: E
authors: Dueger
authors: Grace E
authors: GE
authors: Macalino
authors: Silvia M
authors: SM
authors: Montano
authors: Drake H
authors: DH
authors: Tilley
authors: Margaret
authors: M
authors: Mbuchi
authors: Eyako K
authors: EK
authors: Wurapa
authors: Karen
authors: K
authors: Saylors
authors: Christopher C
authors: CC
authors: Duplessis
authors: Naiki
authors: N
authors: Puplampu
authors: Eric C
authors: EC
authors: Garges
authors: R Scott
authors: RS
authors: McClelland
authors: Jose L
authors: JL
authors: Sanchez
mesh_terms: D000900:Anti-Bacterial Agents; D015730:Djibouti / Q000453:epidemiology; D024901:Drug Resistance, Multiple, Bacterial; D005260:Female; D005869:Ghana / Q000453:epidemiology; D006069:Gonorrhea / Q000453:epidemiology* / Q000382:microbiology*; D006801:Humans; D007630:Kenya / Q000453:epidemiology; D008297:Male; D008826:Microbial Sensitivity Tests; D008887:Military Medicine; D009344:Neisseria gonorrhoeae; D010568:Peru / Q000453:epidemiology; D011159:Population Surveillance; D014481:United States / Q000453:epidemiology; D014521:Urethra / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents