title: Structures of acylated sucroses and an acylated flavonol glycoside and inhibitory effects of constituents on aldose reductase from the flower buds of Prunus mume.
abstract: Five new acylated sucroses, mumeoses K-O, and a new acylated flavonol glycoside, mumeflavonoside A, were isolated from the flower buds of Prunus mume, cultivated in Zhejiang province, China. The chemical structures of the new compounds were elucidated on the basis of chemical and physicochemical evidence. The inhibitory effects of the isolated acylated sucroses and flavonol glycosides on aldose reductase were also investigated. Several flavonol glycosides including mumeflavonoside A were shown to inhibit aldose reductase.
authors: Department of Pharmacognosy, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto, 607-8412, Japan.
authors: Seikou
authors: S
authors: Nakamura
authors: Katsuyoshi
authors: K
authors: Fujimoto
authors: Takahiro
authors: T
authors: Matsumoto
authors: Tomoe
authors: T
authors: Ohta
authors: Keiko
authors: K
authors: Ogawa
authors: Haruka
authors: H
authors: Tamura
authors: Hisashi
authors: H
authors: Matsuda
authors: Masayuki
authors: M
authors: Yoshikawa
mesh_terms: D000215:Acylation; D000449:Aldehyde Reductase / Q000037:antagonists & inhibitors*; D000818:Animals; D002681:China; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000494:pharmacology; D044948:Flavonols / Q000737:chemistry* / Q000494:pharmacology; D035264:Flowers / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry* / Q000494:pharmacology; D027861:Prunus / Q000737:chemistry*; D051381:Rats; D013395:Sucrose / Q000737:chemistry*
chemical_list: D004791:Enzyme Inhibitors; D044948:Flavonols; D006027:Glycosides; D013395:Sucrose; D000449:Aldehyde Reductase