title: [Radiomodifying properties of deuterium-depleted water with poor content of heavier isotopes of oxygen].
abstract: Experiments were performed with outbreed mice CD-I and hybrid mice (CBA' C57BI)F1. Seven to 21 days before irradiation, the mice had continuously consumed light-isotope water (35 ppm) produced by rectification w/o secondary treatment. Dose of single gamma-irradiation ranged from 4 to 8.5 Gy. The radiomodifying effects included statistically reliable reductions in survivability and life span, loss of body mass, and decreases in marrow myelokaryocytes and peripheral leukocytes. In 8-9 days after irradiation, spleen mass in the experimental mice was found enlarged as compared with the controls.
authors: E I
authors: EI
authors: Kulikova
authors: D M
authors: DM
authors: Kriuchkova
authors: Iu S
authors: IuS
authors: Severiukhin
authors: V N
authors: VN
authors: Gaevskiĭ
authors: A A
authors: AA
authors: Ivanov
mesh_terms: D000818:Animals; D003903:Deuterium / Q000032:analysis*; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D007962:Leukocytes / Q000528:radiation effects*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D010103:Oxygen Isotopes / Q000032:analysis*; D011833:Radiation Injuries, Experimental; D013154:Spleen / Q000528:radiation effects*; D014867:Water / Q000737:chemistry*; D014916:Whole-Body Irradiation / Q000379:methods*
chemical_list: D010103:Oxygen Isotopes; D014867:Water; D003903:Deuterium