title: A solitary mediastinal mass due to localized AL amyloidosis: case report and review of the literature.
abstract: AL amyloidosis presenting as a solitary mediastinal mass is a rare occurrence, with only a few cases reported in the literature. We describe a case of a man presenting with a mediastinal mass diagnosed as amyloidosis, confirmed by mass spectrometry to consist of lambda light chains. Here we review the literature and discuss treatment options for this rare entity.
authors: Department of Medicine, Amyloidosis Center, Boston University School of Medicine and Boston Medical Center, Boston, MA, USA.
authors: Shayna
authors: S
authors: Sarosiek
authors: David C
authors: DC
authors: Seldin
authors: John L
authors: JL
authors: Berk
authors: Vaishali
authors: V
authors: Sanchorawala
mesh_terms: D000368:Aged; D000682:Amyloid / Q000378:metabolism*; D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism; D006801:Humans; D007146:Immunoglobulin lambda-Chains / Q000378:metabolism*; D008297:Male; D008477:Mediastinal Diseases / Q000175:diagnosis / Q000209:etiology* / Q000378:metabolism; D012196:Review Literature as Topic; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D014057:Tomography, X-Ray Computed
chemical_list: D000682:Amyloid; D007146:Immunoglobulin lambda-Chains; C518669:amyloid L, human