title: Rare syringyl acylated flavonol glycosides from the aerial parts of Leonurus japonicus Houtt.
abstract: Five new syringyl acylated flavonol glycosides, named leonurusoides A (1), B (2), C (3), D (4), and E (5), together with one known one 6 were obtained from the aerial parts of Leonurus japonicus. Their structures were elucidated by chemical and spectroscopic methods (UV, IR, HRESI-TOF-MS, 1D and 2D NMR). Compounds 1-6 showed triglyceride (TG) accumulation inhibitory effects in free fatty acid-induced HepG2 cells.
authors: Tianjin State Key Laboratory of Modern Chinese Medicine, 312 Anshanxi Road, Nankai District, Tianjin 300193, China.
authors: Yi
authors: Y
authors: Zhang
authors: Shen
authors: S
authors: Deng
authors: Lu
authors: L
authors: Qu
authors: Ya-Ting
authors: YT
authors: An
authors: Chun-Hua
authors: CH
authors: Wu
authors: Li-Feng
authors: LF
authors: Han
authors: Xiu-Mei
authors: XM
authors: Gao
authors: Tao
authors: T
authors: Wang
mesh_terms: D044948:Flavonols / Q000737:chemistry* / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry* / Q000494:pharmacology; D056945:Hep G2 Cells; D006801:Humans; D031332:Leonurus / Q000737:chemistry*; D050356:Lipid Metabolism / Q000187:drug effects; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D035261:Plant Components, Aerial / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry
chemical_list: D044948:Flavonols; D006027:Glycosides; D010936:Plant Extracts