title: [Description of patients with confirmed influenza A(H1N1)pdm09 admitted to an intensive care unit and identification of severity risk factors].
abstract: OBJECTIVE
  The authors had for objective to describe patients with confirmed influenza A(H1N1)pdm09 admitted to an intensive care unit (ICU) in a university hospital and to identify risk factors correlated with the severity of the disease.
  
  
  METHODS
  A prospective study was conducted in an university hospital during the A(H1N1)pdm09 influenza pandemic. Severe laboratory confirmed cases (admitted to an ICU) were described and compared with non-severe confirmed cases (not admitted to an ICU).
  
  
  RESULTS
  Sixty-nine patients were included; 36 (52%) were 15 to 44 years of age. Sixteen (23%) cases were defined as severe, ten of these (63%) concerned patients 45 to 64 years of age. The independent factors associated with severity were: a history of heart disease, obesity, and tobacco abuse.
  
  
  CONCLUSIONS
  This work reinforces the need to identify and protect groups at risk of severe outcomes.
authors: Unité épidémiologie et biomarqueurs de l'infection, service d'hygiène, épidémiologie et prévention, hospices civils de Lyon, 69437 Lyon cedex 03, France. cecile.payet@univ-lyon1.fr
authors: C
authors: C
authors: Payet
authors: D
authors: D
authors: Lutringer-Magnin
authors: P
authors: P
authors: Cassier
authors: B
authors: B
authors: Lina
authors: L
authors: L
authors: Argaud
authors: B
authors: B
authors: Allaouchiche
authors: P
authors: P
authors: Vanhems
mesh_terms: D000293:Adolescent; D000328:Adult; D015897:Comorbidity; D004196:Disease Outbreaks; D005260:Female; D005602:France / Q000453:epidemiology; D006331:Heart Diseases / Q000453:epidemiology; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D053118:Influenza A Virus, H1N1 Subtype / Q000302:isolation & purification*; D007251:Influenza, Human / Q000453:epidemiology* / Q000821:virology; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology; D011446:Prospective Studies; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology; D055815:Young Adult