title: [Therapeutic innovation in AMD and other retinal diseases].
abstract: Age-related macular degeneration (AMD) is a leading cause of severe visual impairment in individuals over 50 years in developed countries. Latest advances in imaging techniques have led to improved and accurate diagnosis of AMD. We witness a major breakthrough in the treatment of the neovascular form of AMD with the antiangiogenic (anti-VEGF) drugs. However, no therapy is yet available for the atrophic dry form of AMD. Innovative strategies gene therapy, cell therapy, nanotechnology neuroprotection- and multidisciplinary approaches are emerging to prevent the decline in vision in aging populations and its health implications.
authors: Université Pierre-et-Marie-Curie, Paris-6, France.
authors: Jean-François
authors: JF
authors: Girmens
authors: Serge
authors: S
authors: Picaud
authors: José-Alain
authors: JA
authors: Sahel
mesh_terms: D035843:Biomedical Research / Q000639:trends; D003941:Diagnostic Techniques, Ophthalmological / Q000639:trends; D006801:Humans; D008268:Macular Degeneration / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D008954:Models, Biological; D012164:Retinal Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D035703:Therapies, Investigational / Q000379:methods / Q000639:trends*