title: Fulminate heparin-induced thrombocytopenia and surgery with deep hypothermic circulatory arrest using bivalirudin.
abstract: After on-pump coronary artery bypass graft surgery, a patient had acute heparin-induced thrombocytopenia with thoracic arterial and venous thrombus formations. Complex emergency surgery with cardiopulmonary bypass and deep hypothermic circulatory arrest using bivalirudin anticoagulation was performed.
authors: Institute of Anaesthesiology, Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Germany. akoster@hdz-nrw.de
authors: Andreas
authors: A
authors: Koster
authors: Mohammad
authors: M
authors: Amin-Parsa
authors: Michael
authors: M
authors: Kaufmann
authors: Ties
authors: T
authors: Meyer-Jark
authors: Marcus
authors: M
authors: Rudloff
authors: Juergen
authors: J
authors: Diekmann
authors: Wolf-Martin
authors: WM
authors: Georg
authors: Michael
authors: M
authors: Liebke
authors: Uwe
authors: U
authors: Schirmer
authors: Jan F
authors: JF
authors: Gummert
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects; D000991:Antithrombins / Q000008:administration & dosage; D001777:Blood Coagulation; D002315:Cardiopulmonary Bypass; D050792:Circulatory Arrest, Deep Hypothermia Induced / Q000379:methods*; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000601:surgery; D004305:Dose-Response Relationship, Drug; D006493:Heparin / Q000009:adverse effects; D006629:Hirudins / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D010446:Peptide Fragments / Q000008:administration & dosage*; D011994:Recombinant Proteins / Q000008:administration & dosage; D017131:Thrombectomy / Q000379:methods*; D013921:Thrombocytopenia / Q000097:blood / Q000139:chemically induced* / Q000150:complications; D013927:Thrombosis / Q000209:etiology / Q000601:surgery*
chemical_list: D000925:Anticoagulants; D000991:Antithrombins; D006629:Hirudins; D010446:Peptide Fragments; D011994:Recombinant Proteins; D006493:Heparin; C074619:bivalirudin