title: Walking motion of an overdamped active particle in a ratchet potential.
abstract: An active particle can convert its internal energy into mechanical work. We study a generalized energy-depot model of an overdamped active particle in a ratchet potential. Using well-known biological parameters for kinesin-1 and modeling ATP influx as a pulsed energy supply, we apply our model to the molecular motor system. We find that our simple model can capture the essential properties of the kinesin motor such as forward stepping, stalling, backward stepping, dependence on ATP concentration, and stall force. Our model might be quite universal in the sense that it is able to describe dynamics of various types of motors as long as realistic parameters for each motor species are adopted.
authors: Department of Physics, Ewha Womans University, Seoul, 120-750 Korea ; Korea Institute for Advanced Study, Seoul, 130-722 Korea.
authors: Kong-Ju-Bock
authors: KJ
authors: Lee
authors: Chul Koo
authors: CK
authors: Kim
authors: Myung-Hoon
authors: MH
authors: Chung
keywords: Active particle; Energy depot model; Kinesin