title: Impact of different fluoride concentrations and pH of dentifrices on tooth erosion/abrasion in vitro.
abstract: BACKGROUND
  This in vitro study analysed the effect of different fluoride concentrations in acidic or neutral liquid dentifrices in protecting enamel and dentine from erosive and abrasive wear.
  
  
  METHODS
  Bovine enamel and dentine specimens (n = 132) were randomly allocated to 11 groups (each n = 12): experimental liquid dentifrices with 550 ppm F, 1100 ppm F, 5000 ppm F or 0 ppm F/placebo (each at pH 4.5 and pH 7.0); and commercial dentifrices with 550 ppm F (Colgate Baby, pH 7.0), 1100 ppm F (Crest, pH 7.0) and 5000 ppm F (Duraphat, pH 7.0). The specimens were subjected to erosion for 90 seconds, 4 times/day, over 7 days. Immediately after the first and last erosion, the specimens were brushed for 15 seconds using one of the dentifrices. Tooth wear was measured profilometrically (μm) and analysed by ANOVA (p < 0.05).
  
  
  RESULTS
  All fluoridated liquid dentifrices significantly reduced enamel wear compared to the placebo and commercial dentifrices. Only liquid dentifrices with 1100 and 5000 ppm F significantly reduced dentine wear compared to placebo dentifrice. The pH had no effect, but the consistency had a significant impact on the effect of dentifrices.
  
  
  CONCLUSIONS
  Liquid dentifrices with high F concentration appear to be a good option to prevent tooth wear.
authors: Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Brazil.
authors: B M
authors: BM
authors: Moron
authors: S S H
authors: SS
authors: Miyazaki
authors: N
authors: N
authors: Ito
authors: A
authors: A
authors: Wiegand
authors: F
authors: F
authors: Vilhena
authors: M A R
authors: MA
authors: Buzalaf
authors: A C
authors: AC
authors: Magalhães
mesh_terms: D000818:Animals; D002417:Cattle; D003743:Dental Enamel / Q000187:drug effects; D003802:Dentifrices / Q000737:chemistry*; D005459:Fluorides / Q000494:pharmacology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D011897:Random Allocation; D014072:Tooth Abrasion / Q000517:prevention & control*; D014077:Tooth Erosion / Q000517:prevention & control*
chemical_list: D003802:Dentifrices; D005459:Fluorides