title: [Risk of hospitalization among patients with co-occurring psychotic and substance use disorders: a 12-year follow-up].
abstract: OBJECTIVE
  The study aims to analyze the impact of substance use disorders (SUD) on the risk of hospitalization among patients affected by psychotic disorders.
  
  
  METHODS
  During 1995, the patients consecutively admitted to psychiatric hospitalization or to an outpatient visit, were included in the study. Patients were interviewed by a questionnaire with specific reference to Addiction Severity Index (ASI), in order to assess the presence of SUD. During 2008, for each patient, the retrospective assessment of the days and the number of hospitalizations, due to psychiatric cause between 1996 and 2007, was performed.
  
  
  RESULTS
  During 1995, 102 patients were included in the study, 15 patients (14.7%) with a current SUD, 17 patients (16.7%) with a past SUD, and 70 patients (68.6% of the sample) without SUD. The follow-up analysis did not show any statistically significant difference among the three subgroups for what concerns the risk of receiving at least one hospitalization and the risk of involuntary treatment. By contrast, hospitalized patients with current SUD, if compared to hospitalized patients with past SUD or patients without SUD, appeared to have a significantly higher overall number of hospital admissions and days of hospitalization.
  
  
  CONCLUSIONS
  The current SUD group showed, in terms of hospitalizations, worse prognostic profiles than the group without SUD and the group with past SUD. The prominent role of a comprehensive assessment and a therapeutic strategy taking into account the potential negative effect of substance use on the stabilization of psychotic symptoms is therefore confirmed.
authors: Dipartimento di Neuroscienze e Technologie Biomediche, Sezione di Psichiatria, Università di Milano Biocca. f.bartoli@campus.unimib.it
authors: Francesco
authors: F
authors: Bartoli
authors: Silvio
authors: S
authors: Scarone
authors: Massimo
authors: M
authors: Clerici
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000150:complications* / Q000628:therapy; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000150:complications* / Q000628:therapy; D013997:Time Factors