title: Population-based pediatric reference intervals for hematology, iron and transferrin.
abstract: Reference intervals are crucial decision-making tools aiding clinicians in differentiating between healthy and diseased populations. However, for children such values often are lacking or incomplete. Blood samples were obtained from 689 healthy children, aged 6 months to 18 years, recruited in day care centers and schools. Hematology and anemia analytes were measured on the Siemens Advia 2120 and Abbott Architect ci8200 platforms (hemoglobin, erythrocyte volume fraction [EVF], erythrocytes, mean corpuscular volume [MCV], mean corpuscular hemoglobin [MCH], mean corpuscular hemoglobin concentration [MCHC], reticulocytes, leukocytes, lymphocytes, monocytes, neutrophils, eosinophils, basophils, platelets, iron, transferrin, transferrin saturation). Age- and gender-specific pediatric reference intervals were defined by calculating 2.5th and 97.5th percentiles. The data generated is primarily applicable to a Caucasian population, but could be used by any laboratory if verified for the local patient population.
authors: Department of Clinical Chemistry, County Hospital of Falun, Falun, Sweden.
authors: Mattias
authors: M
authors: Aldrimer
authors: Peter
authors: P
authors: Ridefelt
authors: Peo
authors: P
authors: Rödöö
authors: Frank
authors: F
authors: Niklasson
authors: Jan
authors: J
authors: Gustafsson
authors: Dan
authors: D
authors: Hellberg
mesh_terms: D000293:Adolescent; D015415:Biomarkers / Q000097:blood; D001772:Blood Cell Count / Q000592:standards; D002648:Child; D002675:Child, Preschool; D004909:Erythrocyte Indices / Q000502:physiology*; D005260:Female; D006801:Humans; D007223:Infant; D007501:Iron / Q000097:blood* / Q000592:standards; D008297:Male; D012016:Reference Values; D014168:Transferrin / Q000032:analysis* / Q000592:standards; D044465:White People
chemical_list: D015415:Biomarkers; D014168:Transferrin; D007501:Iron