title: Coronary computed tomography angiography using ultra-low-dose contrast media: radiation dose and image quality.
abstract: To analyze the invasiveness and image quality of coronary CT angiography (CCTA) with 80 kV. We enrolled 181 patients with low body weight and low calcium level. Of these, 154 patients were randomly assigned to 1 of 3 groups: 280 HU/80 kV (n = 51); 350 HU/80 kV (n = 51); or 350 HU/120 kV (n = 52). The amount of contrast media (CM) was decided with a CT number-controlling system. Twenty-seven patients were excluded because of an invalid time density curve by timing bolus. The predicted amount of CM, volume CT dose index, dose-length product, effective dose, image noise, and 5-point image quality were measured. The amounts of CM for the 80 kV/280 HU, 80 kV/350 HU, and 120 kV/350 HU groups were 10 ± 4 mL, 15 ± 7 mL, and 30 ± 6 mL, respectively. Although image noise was greater at 80 than 120 kV, there was no significant difference in image quality between 80 kV/350 HU and 120 kV/350 HU (p = 0.390). There was no significant difference in image quality between 80 kV/280 HU and 80 kV/350 HU (4.4 ± 0.7 vs. 4.7 ± 0.4, p = 0.056). The amount of CM and effective dose was lower for 80 kV CCTA than for 120 kV CCTA. CCTA at 80 kV/280 HU may decrease the amount of CM and radiation dose necessary while maintaining image quality.
authors: Cardiovascular Center, Amagasaki Central Hospital, 1-12-1, Shio-e, Amagasaki, Hyogo, 661-0976, Japan. plaquemap@yahoo.co.jp
authors: Sei
authors: S
authors: Komatsu
authors: Teruaki
authors: T
authors: Kamata
authors: Atsuko
authors: A
authors: Imai
authors: Tomoki
authors: T
authors: Ohara
authors: Mitsuhiko
authors: M
authors: Takewa
authors: Ryoko
authors: R
authors: Ohe
authors: Kazuaki
authors: K
authors: Miyaji
authors: Junichi
authors: J
authors: Yoshida
authors: Kazuhisa
authors: K
authors: Kodama
mesh_terms: D000368:Aged; D003287:Contrast Media; D017023:Coronary Angiography / Q000379:methods*; D005260:Female; D006801:Humans; D007472:Iohexol; D007564:Japan; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D011237:Predictive Value of Tests; D011829:Radiation Dosage
chemical_list: D003287:Contrast Media; D007472:Iohexol