title: RANTing about C9orf72.
abstract: A noncoding repeat expansion in the C9orf72 gene is the most common genetic cause of frontotemporal dementia and amyotrophic lateral sclerosis. In this issue of Neuron, Ash et al. (2013) show that despite being noncoding the repeats are translated, leading to widespread neuronal aggregates of the translated proteins.
authors: Reta Lila Weston Laboratories and Department of Molecular Neuroscience, University College London Institute of Neurology, London WC1N 3BG, UK.
authors: Tammaryn
authors: T
authors: Lashley
authors: John
authors: J
authors: Hardy
authors: Adrian M
authors: AM
authors: Isaacs
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics*; D000073885:C9orf72 Protein; D015331:Cohort Studies; D004268:DNA-Binding Proteins / Q000235:genetics; D057180:Frontotemporal Dementia / Q000235:genetics*; D005838:Genotype; D006801:Humans; D009474:Neurons / Q000166:cytology; D011506:Proteins
chemical_list: D000073885:C9orf72 Protein; C568651:C9orf72 protein, human; D004268:DNA-Binding Proteins; D011506:Proteins