title: 'Marker-of-self' functionalization of nanoscale particles through a top-down cellular membrane coating approach.
abstract: We investigate the 'marker-of-self' functionalization of nanoparticles through coating of natural RBC membranes. The membrane translocation approach is shown to be highly efficient and bestows nanoparticles with correctly oriented and functional immunomodulatory proteins such as CD47 at equivalent density to natural RBCs.
authors: Department of NanoEngineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
authors: Che-Ming J
authors: CM
authors: Hu
authors: Ronnie H
authors: RH
authors: Fang
authors: Brian T
authors: BT
authors: Luk
authors: Kevin N H
authors: KN
authors: Chen
authors: Cody
authors: C
authors: Carpenter
authors: Weiwei
authors: W
authors: Gao
authors: Kang
authors: K
authors: Zhang
authors: Liangfang
authors: L
authors: Zhang
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000032:analysis*; D001698:Biomedical Engineering / Q000379:methods; D051928:CD47 Antigen / Q000032:analysis / Q000378:metabolism; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis / Q000737:chemistry*; D004910:Erythrocyte Membrane / Q000737:chemistry / Q000378:metabolism* / Q000502:physiology; D006860:Hydrogen Bonding; D057927:Hydrophobic and Hydrophilic Interactions; D019344:Lactic Acid / Q000737:chemistry; D008264:Macrophages / Q000378:metabolism; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry*; D011100:Polyglycolic Acid / Q000737:chemistry; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer
chemical_list: D015415:Biomarkers; D051928:CD47 Antigen; C497895:Cd47 protein, mouse; D020099:Coated Materials, Biocompatible; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid