title: Mitochondrial ROS fire up T cell activation.
abstract: Metabolic reprogramming has emerged as an important feature of immune cell activation. Two new studies, including Sena et al. (2013) in this issue of Immunity, identify mitochondrial reactive oxygen species (ROS) arising from metabolic reprogramming as signaling molecules in T cell activation.
authors: MRC Mitochondrial Biology Unit, MRC/Wellcome Trust Building, Hills Road, Cambridge CB2 0XY, UK.
authors: Michael P
authors: MP
authors: Murphy
authors: Richard M
authors: RM
authors: Siegel