title: Diagnostic value of open biopsy for malignant T-cell lymphoma of the liver.
abstract: A 62-year-old man was referred to our hospital because of pain in the right upper quadrant. Laboratory tests revealed normal levels of tumor markers. Abdominal ultrasonography showed a hypoechoic mass of approximately 9 cm in diameter in the right lobe of the liver. Computed tomography revealed a low-density mass with peripheral enhancement in the posterior segment of the right lobe. Magnetic resonance imaging showed a low-intensity mass on T(1)-weighted images and a high-intensity mass on T(2)-weighted images. Abdominal angiography showed enhanced staining only at the periphery of the tumor. An open biopsy was performed and intraoperative examination of frozen sections indicated malignant lymphoma. The histopathologic diagnosis was malignant T-cell lymphoma. After combined chemotherapy, the tumor shrank to 4 cm in diameter. To our knowledge, only 15 cases of malignant T-cell lymphoma have been reported previously. Diagnosis is particularly challenging because this type of tumor has no distinctive imaging characteristics or signs or symptoms. This case emphasizes the need to include malignant T-cell lymphoma in the differential diagnosis and demonstrates the importance of open biopsy in patients with a suspected liver tumor.
authors: Departments of       1 Digestive Surgery.
authors: Akihisa
authors: A
authors: Hojo
authors: Hisashi
authors: H
authors: Nakayama
authors: Osamu
authors: O
authors: Aramaki
authors: Tokio
authors: T
authors: Higaki
authors: Masamichi
authors: M
authors: Moriguchi
authors: Masahiko
authors: M
authors: Sugitani
authors: Katsuhiro
authors: K
authors: Miura
authors: Jin
authors: J
authors: Takeuchi
authors: Ryu
authors: R
authors: Nishiyama
authors: Mitsuhiko
authors: M
authors: Moriyama
authors: Tadatoshi
authors: T
authors: Takayama
mesh_terms: D001706:Biopsy; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D016399:Lymphoma, T-Cell / Q000473:pathology*; D008297:Male; D008875:Middle Aged