title: Association between nonalcoholic fatty liver disease and coronary artery disease complexity in patients with acute coronary syndrome: a pilot study.
abstract: Nonalcoholic fatty liver disease (NAFLD) is highly prevalent in patients with acute coronary syndrome (ACS). We assessed the association between NAFLD and SYNTAX Score (SS) in patients with ACS. Eighty consecutive patients with ACS were enrolled. Patients were evaluated using ultrasound to detect NAFLD and hepatosteatosis stage. The prevalence of NAFLD was 81.2%; median SS was 15. The SS was significantly higher in patients with NAFLD (18 ± 8 vs. 11 ± 5, P = .001). Univariate analysis showed that the stage of NAFLD correlated with SS (r = .6, P < .001). In multivariate binary logistic analysis, increased age (odds ratio [OR], 1.05; 95% confidence interval [CI],1.00-1.10) and presence of NAFLD (OR, 13.20; 95% CI, 2.52-69.15) were independent factors associated with supramedian SS. In conclusion, among patients with ACS, those with NAFLD have more complex CAD as assessed by SS.
authors: 1Department of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, Turkey.
authors: Mustafa Tarik
authors: MT
authors: Agaç
authors: Levent
authors: L
authors: Korkmaz
authors: Gökhan
authors: G
authors: Cavusoglu
authors: Ayse Gül
authors: AG
authors: Karadeniz
authors: Süret
authors: S
authors: Agaç
authors: Hüseyin
authors: H
authors: Bektas
authors: Hakan
authors: H
authors: Erkan
authors: Mustafa Oguz
authors: MO
authors: Varol
authors: Mehmet Bulent
authors: MB
authors: Vatan
authors: Zeydin
authors: Z
authors: Acar
authors: Umit
authors: U
authors: Mentese
authors: Sükrü
authors: S
authors: Celik
mesh_terms: D054058:Acute Coronary Syndrome / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000628:therapy; D000368:Aged; D015897:Comorbidity; D017023:Coronary Angiography; D005234:Fatty Liver / Q000000981:diagnostic imaging / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D065626:Non-alcoholic Fatty Liver Disease; D062645:Percutaneous Coronary Intervention; D010865:Pilot Projects; D015995:Prevalence; D012307:Risk Factors; D012720:Severity of Illness Index; D014463:Ultrasonography
keywords: SYNTAX score; acute coronary syndrome; nonalcoholic fatty liver disease