title: An overview of control strategy and diagnostic technology for foot-and-mouth disease in China.
abstract: Foot-and-mouth disease (FMD) is one of most contagious animal diseases. It affects millions of cloven-hoofed animals and causes huge economic losses in many countries of the world. There are seven serotypes of which three (O, A and Asia 1) are endemic in China. Efficient control of FMD in China is crucial for the prevention and control of FMD in Asia and throughout the world. For the control of FMD, a powerful veterinary administration, a well-trained veterinary staff, a system of rapid and accurate diagnostic procedures and, in many countries, compulsory vaccination of susceptible animals are indispensable. This article strives to outline the Chinese animal disease control and prevention system, in particular for FMD, with the emphasis on diagnostic procedures applied in Chinese laboratories. In addition, new technologies for FMD diagnosis, which are currently in the phase of development or in the process of validation in Chinese laboratories, are described, such as lateral flow devices (LFD), Mab-based ELISAs, reverse transcription loop-mediated isothermal amplification (RT-LAMP) and gold nanopariticle immuno-PCR (GNP-IPCR).
authors.affiliation: OIE/China National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China.
authors.forename: Yao-Zhong
authors.initials: YZ
authors.lastname: Ding
authors.forename: Hao-Tai
authors.initials: HT
authors.lastname: Chen
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Zhou
authors.forename: Li-Na
authors.initials: LN
authors.lastname: Ma
authors.forename: Liang
authors.initials: L
authors.lastname: Zhang
authors.forename: Yuanxin
authors.initials: Y
authors.lastname: Gu
authors.forename: Yong-Sheng
authors.initials: YS
authors.lastname: Liu
mesh_terms: D000818:Animals; D002681:China / Q000453:epidemiology; D003140:Communicable Disease Control / Q000191:economics / Q000295:instrumentation / Q000379:methods*; D019937:Diagnostic Techniques and Procedures / Q000191:economics / Q000295:instrumentation / Q000662:veterinary*; D005536:Foot-and-Mouth Disease / Q000175:diagnosis* / Q000453:epidemiology / Q000517:prevention & control* / Q000821:virology; D029544:Foot-and-Mouth Disease Virus / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology; D058751:Livestock / Q000821:virology