title: Combination of intracranial translucency and 3D sonography in the first trimester diagnosis of neural tube defects: case report and review of literature.
abstract: Neural tube defects are congenital defects of the central nervous system caused by lack of neural tube closure. First trimester screening for aneuploidy has become widespread in the recent years. Fetal intracranial translucency (IT) can be easily observed in normal fetuses in the mid-sagittal plane. The absence of IT should be an important factor taken into consideration in the early diagnosis of open spinal defects. 3D ultrasonography is especially useful in cases of spinal anomalies where the visualization of the fetal structure is insufficient due to fetal position. We present a combination of intracranial translucency and 3D sonography used in the first trimester diagnosis of a neural tube defect case.
authors.affiliation: Ege Universitiy Faculty of Medicine, Department of Obstetrics and Gynecology, Bornmova, Izmir, Turkey.
authors.forename: Nuri
authors.initials: N
authors.lastname: Peker
authors.forename: Ahmet Ozgur
authors.initials: AO
authors.lastname: Yeniel
authors.forename: Mete
authors.initials: M
authors.lastname: Ergenoglu
authors.forename: Seda
authors.initials: S
authors.lastname: Hurşitoğlu
authors.forename: Fuat
authors.initials: F
authors.lastname: Akercan
authors.forename: Nedim
authors.initials: N
authors.lastname: Karadadaş
mesh_terms: D000328:Adult; D001933:Brain Stem / Q000000981:diagnostic imaging* / Q000196:embryology*; D005260:Female; D005333:Fetus / Q000002:abnormalities* / Q000648:ultrastructure*; D006801:Humans; D009436:Neural Tube Defects / Q000000981:diagnostic imaging*; D048208:Nuchal Translucency Measurement; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D016216:Ultrasonography, Prenatal