title: Preparation and evaluation of natural scaffold materials for kidney regenerative applications.
abstract: Tissue engineering involves the concerted action of biomaterials, cells, and growth factors. Kidney -regeneration relies on the same combination of ingredients. Here, we describe an example of gelatin-based biomaterial preparation and its evaluation in the context of kidney biocompatibility and integration. This biomaterial manufacturing technique is simple, cost-effective, highly reproducible and the in vivo evaluation procedure highly informative on the biocompatibility and regenerative potential of the tested construct.
authors.affiliation: Allergan Medical, Medford, MA, USA.
authors.forename: Monica A
authors.initials: MA
authors.lastname: Serban
authors.forename: Toyin A
authors.initials: TA
authors.lastname: Knight
authors.forename: Richard G
authors.initials: RG
authors.lastname: Payne
mesh_terms: D005780:Gelatin; D006801:Humans; D007668:Kidney / Q000502:physiology*; D008863:Microspheres; D012038:Regeneration / Q000502:physiology*; D044968:Regenerative Medicine / Q000379:methods*; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds
chemical_list: D005780:Gelatin