title: [Acute skin detachment in a newborn].
abstract: Acute blistering and erosion in a newborn is one of the few emergency cases seen in dermatology. It is important to differentiate between infectious causes, congenital abnormalities, autoimmune bullous dermatitis, immunological skin diseases and skin burns within 24 hours. In this clinical lesson, we present a case of acute skin detachment in a newborn caused by staphylococcal scalded skin syndrome (SSSS). Our patient was a six-day-old boy who had developed flaccid blisters around the umbilicus, which ruptured on minimal friction. Generalised superficial erosions on the face, hands and feet arose within hours. Based on the clinical presentation combined with a subcorneal blister found on histopathological examination and a positive culture for Staphylococcus aureus on nasal and umbilical smears, the diagnosis of SSSS was made. Our patient was treated successfully with flucloxacillin and gentamicin; the skin lesions healed without scarring within six days.
authors.affiliation: UMC Groningen, afd. Dermatologie, Centrum voor blaarziekten, Groningen, the Netherlands. m.f.jonkman@umcg.nl
authors.forename: A Susanne
authors.initials: AS
authors.lastname: Aalfs
authors.forename: Marcel F
authors.initials: MF
authors.lastname: Jonkman
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005436:Floxacillin / Q000627:therapeutic use; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D013206:Staphylococcal Scalded Skin Syndrome / Q000175:diagnosis* / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins; D005436:Floxacillin