title: Comparative metabolite profiling and chemical study of Ramalina siliquosa complex using LC-ESI-MS/MS approach.
abstract: A chemical study of the lichen Ramalina siliquosa complex found in Brittany was conducted. Eight chemotypes were considered and their chemical composition was elucidated for the first time by LC-MS analysis. Ten main compounds were identified: conhypoprotocetraric acid (1), salazinic acid (2), peristictic acid (3), cryptostictic acid (4), protocetraric acid (5), stictic acid (6), norstictic acid (7), hypoprotocetraric acid (8), 4-O-demethylbarbatic acid (9), (+)-usnic acid (10) and 22 minor compounds were reported. The MS/MS fragmentation patterns of each compound of R. siliquosa complex were determined and proposed.
authors.affiliation: Equipe PNSCM Produits naturels - Synthèses - Chimie Médicinale, UMR CNRS 6226, Institut des Sciences chimiques de Rennes, UFR Sciences Pharmaceutiques et Biologiques, Univ. Rennes 1, Université Européenne de Bretagne, 2 Avenue du Pr. Léon Bernard, F-35043 Rennes, France.
authors.forename: Delphine
authors.initials: D
authors.lastname: Parrot
authors.forename: Saleem
authors.initials: S
authors.lastname: Jan
authors.forename: Nicolas
authors.initials: N
authors.lastname: Baert
authors.forename: Sylvain
authors.initials: S
authors.lastname: Guyot
authors.forename: Sophie
authors.initials: S
authors.lastname: Tomasi
mesh_terms: D001203:Ascomycota / Q000737:chemistry* / Q000378:metabolism*; D002853:Chromatography, Liquid; D055432:Metabolomics; D021241:Spectrometry, Mass, Electrospray Ionization; D053719:Tandem Mass Spectrometry