title: Synthesis and concentration dependent antibacterial activities of CuO nanoflakes.
abstract: We report, synthesis and antibacterial activities of CuO nanoflakes. CuO nanoparticles are prepared at room temperature through sol-gel method. X-ray diffraction studies show the particles are monoclinic (crystalline) in nature. Scanning electron microscopy (SEM) images clearly show that the prepared particles are flake like in structure. Fourier transform infrared (FTIR) spectra exhibits three different bands that correspond to the Au and Bu modes. Antibacterial studies were performed on Shigella flexneri, Staphylococcus aureus, Staphylococcus epidermidis, Salmonella typhimurium, Bacillus subtilis, Escherichia coli, Vibrio cholera, Pseudomonas aeruginosa and Aeromonas liquefaciens bacterial strains. Among these bacterial strains, S. flexneri and B. subtilis are most sensitive to copper oxide nanoparticles than the positive control (Penicillin G) and S. typhimurium strain shows the less sensitive. Results show that sensitivity is highly dependent on the concentrations of CuO nanoflakes.
authors.affiliation: Department of Physics, National Institute of Technology, Tiruchirappalli 620 015, India.
authors.forename: T
authors.initials: T
authors.lastname: Pandiyarajan
authors.forename: R
authors.initials: R
authors.lastname: Udayabhaskar
authors.forename: S
authors.initials: S
authors.lastname: Vignesh
authors.forename: R Arthur
authors.initials: RA
authors.lastname: James
authors.forename: B
authors.initials: B
authors.lastname: Karthikeyan
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D003300:Copper / Q000737:chemistry* / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D013052:Spectrometry, X-Ray Emission; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D003300:Copper; C000520:cuprous oxide