title: FDG-PET/CT imaging biomarkers in head and neck squamous cell carcinoma.
abstract: This article discusses the value of18F-fluoro-2-deoxyglucose PET/CT imaging biomarkers in head and neck squamous cell carcinoma.18F-fluoro-2-deoxyglucose PET/CT is valuable at baseline staging, radiotherapy planning, therapy response assessment and in the follow-up of patients with head and neck squamous cell carcinoma. Maximum and peak standardized uptake value (SUVmaxand SUVpeak), metabolic tumor volume and total lesion glycolysis are the common18F-fluoro-2-deoxyglucose quantitative parameters that have been studied, along with qualitative assessments. These parameters will be evaluated with respect to their established or potential role as noninvasive biomarkers for patient risk stratification, treatment response and survival outcome.
authors.affiliation: Russel H Morgan Department of Radiology & Radiology Science, Johns Hopkins Medical Institutions, 601 North Caroline Street/JHOC 3235, Baltimore, MD 21287, USA.
authors.forename: Vasavi
authors.initials: V
authors.lastname: Paidpally
authors.forename: Alin
authors.initials: A
authors.lastname: Chirindel
authors.forename: Stella
authors.initials: S
authors.lastname: Lam
authors.forename: Nishant
authors.initials: N
authors.lastname: Agrawal
authors.forename: Harry
authors.initials: H
authors.lastname: Quon
authors.forename: Rathan M
authors.initials: RM
authors.lastname: Subramaniam
keywords: FDG; PET/CT; head and neck squamous cell carcinoma; imaging biomarkers