title: Interplay between experimental dental pellicles and stannous-containing toothpaste on dental erosion-abrasion.
abstract: The interaction between stannous-containing dentifrice slurry and experimentally formed pellicles was investigated on enamel and root dentin using an erosion-remineralization-abrasion cycling model. The remineralizing solutions contained no proteins (negative control), mucin, casein, mucin + casein or albumin, for experimental pellicle formation. Toothbrushing was performed with fluoride toothpaste, with (TP + Sn) and without (TP) 3,500 ppm Sn. TP + Sn reduced surface loss for both enamel and root dentin (p < 0.05). The association between TP + Sn and albumin resulted in a significantly lower enamel surface loss (p < 0.05), suggesting positive interaction of stannous ion and albumin on dental erosion-abrasion protection. A similar trend was observed for root dentin, although less pronounced.
authors.affiliation: Oral Health Research Institute, Department of Preventive and Community Dentistry, Indiana University School of Dentistry, Indianapolis, Ind. 46202-2876, USA. ahara@iupui.edu
authors.forename: A T
authors.initials: AT
authors.lastname: Hara
authors.forename: F
authors.initials: F
authors.lastname: Lippert
authors.forename: D T
authors.initials: DT
authors.lastname: Zero
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D002364:Caseins / Q000494:pharmacology; D003743:Dental Enamel; D044622:Dental Pellicle / Q000737:chemistry / Q000502:physiology; D003804:Dentin; D006801:Humans; D008892:Milk / Q000737:chemistry; D009077:Mucins / Q000494:pharmacology; D012471:Salivary Proteins and Peptides / Q000737:chemistry / Q000502:physiology; D012710:Serum Albumin, Bovine / Q000494:pharmacology*; D012969:Sodium Fluoride / Q000627:therapeutic use; D017971:Tin Compounds / Q000627:therapeutic use*; D014072:Tooth Abrasion / Q000517:prevention & control; D014077:Tooth Erosion / Q000517:prevention & control*; D014089:Tooth Remineralization; D014092:Tooth Root; D014100:Toothpastes / Q000737:chemistry / Q000627:therapeutic use*
chemical_list: D002364:Caseins; D009077:Mucins; D012471:Salivary Proteins and Peptides; D017971:Tin Compounds; D014100:Toothpastes; C023599:stannous chloride; D012710:Serum Albumin, Bovine; D012969:Sodium Fluoride