title: Prospective evaluation of magnetic resonance enterography for the detection of mesenteric small bowel tumours.
abstract: OBJECTIVE
  To prospectively evaluate magnetic resonance (MR) enterography for detecting mesenteric small-bowel tumours (MSBTs) and assess the added value of gadolinium-chelate injection.
  
  
  METHODS
  Over a 2-year period MR enterography examinations of 75 patients (33 men, 42 women; mean age, 53.8 years; range, 19-85) with suspected MSBT were blindly analysed by two readers for the presence of MSBT. Sensitivities, specificities, predictive positive values (PPVs), negative predictive values (NPVs) and accuracies of MR enterography for the detection of MSBT were calculated on per-patient and per-lesion bases. The McNemar test was used to compare sensitivities and specificities of the unenhanced and gadolinium-enhanced sets of MR enterographies.
  
  
  RESULTS
  Thirty-seven MSBTs were pathologically confirmed in 26 patients. The mean tolerance score of the examinations was 0.7. On a per-patient basis, sensitivity, specificity, PPV, NPV and accuracy for detection of MSBT were 96 % [95 % CI, 89-100 %], 96 % [90-100 %], 93 % [83-100 %], 98 % [94-100 %] and 96 % [92-100 %], respectively. On a per-lesion basis, sensitivity and PPV were 70 % [56-85 %] and 93 % [83-100 %], respectively. Gadolinium injection yielded higher sensitivities on both bases (P = 0.008).
  
  
  CONCLUSIONS
  MR enterography is an accurate and well-tolerated imaging modality for detecting MSBT. Intravenous administration of gadolinium-chelate improves sensitivity for MSBT detection.
  
  
  CONCLUSIONS
  • MR enterography accurately detects mesenteric small bowel tumours. • MR enterography is a well-tolerated imaging technique. • Intravenous administration of gadolinium chelate improves sensitivity for detecting small-bowel tumours.
authors.affiliation: Department of Radiology, Hôpital Robert Debré, Avenue du Général Koenig, 51092 Reims Cedex, France. elisa.amzallag@gmail.com
authors.forename: Elisa
authors.initials: E
authors.lastname: Amzallag-Bellenger
authors.forename: Philippe
authors.initials: P
authors.lastname: Soyer
authors.forename: Coralie
authors.initials: C
authors.lastname: Barbe
authors.forename: Marie-Danièle
authors.initials: MD
authors.lastname: Diebold
authors.forename: Guillaume
authors.initials: G
authors.lastname: Cadiot
authors.forename: Christine
authors.initials: C
authors.lastname: Hoeffel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002614:Chelating Agents; D005260:Female; D005682:Gadolinium; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007414:Intestinal Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D007421:Intestine, Small / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008643:Mesentery; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012016:Reference Values; D012680:Sensitivity and Specificity; D055815:Young Adult
chemical_list: D002614:Chelating Agents; D005682:Gadolinium