title: Effect of coenzyme Q10 on the proteomic profile of the cytosolic and microsomal fractions from rat hepatocytes upon dietary consumption of various lipid components during ontogeny.
abstract: We studied proteomic features of subcellular fractions from rat hepatocytes and intensity of enzymatic and non-enzymatic free radical oxidation depending on the type of dietary fat during adaptation of animals to modified nutrition. Our results illustrate the formation of specific nutriproteomes in the microsomal and cytosolic fractions of rat hepatocytes (measurement of the macro-component and micro-component composition of diet).
authors.affiliation: Institute of Nutrition, Russian Academy of Medical Sciences, Moscow, Russia. sharanova.natalia@gmail.com
authors.forename: N E
authors.initials: NE
authors.lastname: Sharanova
authors.forename: S N
authors.initials: SN
authors.lastname: Kulakova
authors.forename: V A
authors.initials: VA
authors.lastname: Baturina
authors.forename: I Yu
authors.initials: IY
authors.lastname: Toropygin
authors.forename: E A
authors.initials: EA
authors.lastname: Khriapova
authors.forename: A V
authors.initials: AV
authors.lastname: Vasilyev
authors.forename: M M G
authors.initials: MM
authors.lastname: Gapparov
mesh_terms: D000818:Animals; D003600:Cytosol / Q000187:drug effects; D004032:Diet; D004041:Dietary Fats; D005609:Free Radicals / Q000737:chemistry; D022781:Hepatocytes / Q000187:drug effects / Q000378:metabolism*; D050356:Lipid Metabolism / Q000187:drug effects*; D008055:Lipids / Q000737:chemistry; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008297:Male; D040901:Proteomics; D051381:Rats; D013347:Subcellular Fractions / Q000187:drug effects; D014451:Ubiquinone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology
chemical_list: D004041:Dietary Fats; D005609:Free Radicals; D008055:Lipids; D014451:Ubiquinone; C024989:coenzyme Q10