title: Allium sativumL.: the anti-immature leech (Limnatis nilotica) activity compared to Niclosomide.
abstract: This study was carried out to determine the effects of methanolic extracts ofAllium sativumL. onLimnatis niloticacompared with Niclosomide. In this experimental study in September 2010, a number of leeches (70 in total) from the southern area of Ilam province were prepared, and the effects of methanolic extract ofA. sativumL. with Niclosomide as the control drug were compared and distilled water was evaluated as the placebo group which investigatedL. niloticausing anti-leech assay. The average time of paralysis and death ofL. niloticafor Niclosomide (1,250 mg/kg) and the methanol extract ofA. sativumL. (600 μg/ml) were 6.22 ± 2.94 and 68.44 ± 28.39 min, respectively. Distilled water and garlic tablets at a dose of 400 mg were determined as the inert group. In this research, the attraction time of the leeches' death among different treatments is significant. In this study, it was determined that Niclosomide, with an intensity of 4+, and methanolic extracts ofA. sativumL., with an intensity of 3+, have a good anti-leech effect and can be shown to be effective in cases of leech biting, while distilled water was negative.
authors.affiliation: Young Researchers Club, Shahrekord Branch, Islamic Azad University, Iran.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Bahmani
authors.forename: Javad
authors.initials: J
authors.lastname: Abbasi
authors.forename: Ava
authors.initials: A
authors.lastname: Mohsenzadegan
authors.forename: Sirous
authors.initials: S
authors.lastname: Sadeghian
authors.forename: Majid Gholami
authors.initials: MG
authors.lastname: Ahangaran
keywords: Allium sativum L.; Limnatis nilotica; Niclosomide; Paralysis and death