title: Effects of extracts of ginkgo, onion, and celery on the contractility of isolated rat atria.
abstract: The acute negative inotropic and chronotropic effects of the commercial extract of ginkgo leaf (Gingium(®)) and ethanolic extracts of onion bulbs and celery root on spontaneous and noradrenalin-stimulated contractions of the Wistar rat atria were investigated. All analyzed extracts exerted negative inotropic effects on the isolated rat atria. Among the tested extracts, the extract of ginkgo showed the strongest negative inotropic effects on rat atria, either in spontaneous or noradrenalin-induced contractions, being more potent than the onion and celery extracts, respectively.
authors.affiliation: Department of Physiology, Medical Faculty, University of Niš , Nis , Serbia.
authors.forename: Mirjana
authors.initials: M
authors.lastname: Radenković
authors.forename: Dušanka
authors.initials: D
authors.lastname: Kitić
authors.forename: Milica
authors.initials: M
authors.lastname: Kostić
authors.forename: Ana
authors.initials: A
authors.lastname: Mrkaić
authors.forename: Dragana
authors.initials: D
authors.lastname: Pavlović
authors.forename: Bojana
authors.initials: B
authors.lastname: Miladinović
authors.forename: Suzana
authors.initials: S
authors.lastname: Branković
mesh_terms: D000818:Animals; D000077102:Apium; D003864:Depression, Chemical; D020441:Ginkgo biloba; D006321:Heart / Q000187:drug effects*; D006325:Heart Atria / Q000187:drug effects; D009200:Myocardial Contraction / Q000187:drug effects*; D019697:Onions; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves; D018517:Plant Roots; D051381:Rats; D017208:Rats, Wistar
chemical_list: D010936:Plant Extracts; C551075:gingium