title: [Hypoglycemic treatment in type 2 diabetes patients suffering from moderate to severe renal failure in France. Aim of the study].
abstract: The purpose of this study is to describe the hypoglycemic agents prescribed to type 2 diabetes patients (T2D) with renal impairment (RI).
  
  
  METHODS
  Data were extracted from the database LPD-CEGEDIM, based on a sample of 1200 general practitioners. The analysis focused on T2D patients with RI, defined by a glomerular filtration rate (GFR) below 60 mL/min/1.73 m², estimated by the MDRD formula.
  
  
  RESULTS
  Of the 36 255 patients identified with T2D, a GFR was calculated for 8 647 patients (23.9%), 1 472 (22%) with a moderate RI (GFR=[30mL/min/1.73 m²-60mL/min/1.73 m²]) and 86 (1.0%) with a severe RI (GFR=[15mL/min/1.73 m-30mL/min/1.73 m²]); 47,6% of T2D patients with a moderate RI and 52,3% of T2D patients with a severe RI were treated with at least one drug contraindicated in patients with moderate or severe RI.
  
  
  CONCLUSIONS
  These findings suggest better informing doctors of these contraindications and show the value of having new hypoglycemic drugs that can be used in case of RI.
authors.affiliation: Cemka-Eval, Bourg la Reine, France. stephane.bouee@cenka.fr
authors.forename: Stéphane
authors.initials: S
authors.lastname: Bouée
authors.forename: Anne-Françoise
authors.initials: AF
authors.lastname: Gaudin
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Amelineau
authors.forename: Fabrice
authors.initials: F
authors.lastname: Bonnet
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000075202:Contraindications; D016208:Databases, Factual; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D051437:Renal Insufficiency / Q000503:physiopathology*; D012720:Severity of Illness Index
chemical_list: D007004:Hypoglycemic Agents