title: Proton beam therapy and localised prostate cancer: current status and controversies.
abstract: Proton therapy is a promising, but costly, treatment for prostate cancer. Theoretical physical advantages exist; yet to date, it has been shown only to be comparably safe and effective when compared with the alternatives and not necessarily superior. If clinically meaningful benefits do exist for patients, more rigorous study will be needed to detect them and society will require this to justify the investment of time and money. New technical advances in proton beam delivery coupled with shortened overall treatment times and declining device costs have the potential to make this a more cost-effective therapy in the years ahead.
authors.affiliation: Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. jefstathiou@partners.org
authors.forename: J A
authors.initials: JA
authors.lastname: Efstathiou
authors.forename: P J
authors.initials: PJ
authors.lastname: Gray
authors.forename: A L
authors.initials: AL
authors.lastname: Zietman
mesh_terms: D017048:Health Care Costs; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000191:economics / Q000532:radiotherapy*; D061766:Proton Therapy