title: [LUTS in BPH patients with histological prostatitis before and after transurethral resection of the prostate].
abstract: OBJECTIVE
  To investigate the effects of transurethral resection of the prostate (TURP) on lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH) complicated by histological prostatitis.
  
  
  METHODS
  This study included 432 cases of BPH pathologically confirmed after TURP. Excluding those with LUTS-related factors before and after surgery and based on the international prostatitis histological classification of diagnostic criteria, the remaining 144 cases were divided into groups A (pure BPH, n = 30), B (mild inflammation, n = 55), C (moderate inflammation, n = 31), and D (severe inflammation, n = 28). Each group was evaluated for LUTS by IPSS before and a month after surgery.
  
  
  RESULTS
  A total of 399 cases (92.4%) were diagnosed as BPH with histological prostatitis, 269 (67.4%) mild, 86 (21.6%) moderate and 44 (11.0%) severe. The preoperative IPSS was 21.43 +/- 6.09 in group A, 21.75 +/- 5.97 in B, 27.84 +/- 4.18 in C and 31.00 +/- 2.92 in D, with statistically significant differences among different groups (P < 0.001) except between A and B (P = 1.000); the postoperative IPSS was 5.60 +/- 2.16 in A, 7.36 +/- 2.77 in B, 11.55 +/- 3.39 in C and 16.89 +/- 3.37 in D, with statistically significant differences among different groups (P < 0.01), and remarkably lower than the preoperative one (P < 0.001). Almost all the infiltrating inflammatory cells in BPH with histological prostatitis were lymphocytes.
  
  
  CONCLUSIONS
  BPH is mostly complicated with histological chronic prostatitis. The severity of LUTS is higher in BPH patients with histological prostatitis than in those without before and after TURP, and positively correlated with the grade of inflammation. Those complicated with moderate or severe histological prostatitis should take medication for the management of LUTS.
authors.affiliation: Department of Urology, The Eighth Hospital Affiliated to Guangxi Medical University/Guigang People's Hospital, Guigang, Guangxi 537100, China.
authors.forename: Xiang-Hua
authors.initials: XH
authors.lastname: Huang
authors.forename: Bin
authors.initials: B
authors.lastname: Qin
authors.forename: Yi-Wen
authors.initials: YW
authors.lastname: Liang
authors.forename: Qing-Guo
authors.initials: QG
authors.lastname: Wu
authors.forename: Chang-Zan
authors.initials: CZ
authors.lastname: Li
authors.forename: Gang-Shan
authors.initials: GS
authors.lastname: Wei
authors.forename: Han-Chu
authors.initials: HC
authors.lastname: Ji
authors.forename: Yang-Bing
authors.initials: YB
authors.lastname: Liang
authors.forename: Hong-Qiu
authors.initials: HQ
authors.lastname: Chen
authors.forename: Ting
authors.initials: T
authors.lastname: Guan
mesh_terms: D002908:Chronic Disease; D006801:Humans; D059411:Lower Urinary Tract Symptoms; D008297:Male; D011470:Prostatic Hyperplasia / Q000150:complications / Q000601:surgery*; D011472:Prostatitis / Q000150:complications / Q000601:surgery*; D020728:Transurethral Resection of Prostate; D016896:Treatment Outcome