title: Revealing the mechanism of tissue damage due to tobacco use: finally, a smoking gun?
abstract: This commentary highlights the article by Li et al that presents a compelling case for a mechanism by which tobacco smoke extract (TSE) induces damage to the extracellular matrix, a key element in the pathogenesis of tobacco-related disease.
authors.affiliation: Susan Lehman Cullman Laboratory for Cancer Research, Ernest Mario School of Pharmacy, Rutgers University, 164 Frelinghuysen Rd., Piscataway, NJ 08854, USA. furmansk@rci.rutgers.edu
authors.forename: Philip
authors.initials: P
authors.lastname: Furmanski
mesh_terms: D055252:Cell-Derived Microparticles / Q000378:metabolism*; D006801:Humans; D008264:Macrophages / Q000378:metabolism*; D059748:Proteolysis; D012907:Smoking