title: Daptomycin non-susceptible Staphylococcus aureus at a US medical centre.
abstract: Daptomycin non-susceptible Staphylococcus aureus was rarely encountered at our medical centre until 2010, when 10 isolates (0.4% of S. aureus) were confirmed by E-test as non-susceptible. These isolates were not of the same strain type and there was no link between the 10 patients. Daptomycin non-susceptibility may be increasing.
authors.affiliation: Infectious Disease, Orlando Health, Orlando, FL, USA.
authors.forename: A
authors.initials: A
authors.lastname: Velazquez
authors.forename: C A
authors.initials: CA
authors.lastname: DeRyke
authors.forename: R
authors.initials: R
authors.lastname: Goering
authors.forename: V
authors.initials: V
authors.lastname: Hoover
authors.forename: M R
authors.initials: MR
authors.lastname: Wallace
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002648:Child; D017576:Daptomycin / Q000494:pharmacology* / Q000627:therapeutic use; D024881:Drug Resistance, Bacterial; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification*; D014481:United States; D014640:Vancomycin / Q000627:therapeutic use; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin; D017576:Daptomycin
keywords: Antibiotic resistance; daptomycin; daptomycin resistance; staphylococcus aureus treatment; vancomycin