title: Acute sinusitis in children.
abstract: Acute rhinosinusitis is a common illness in children. Viral upper respiratory tract infection is the most common presentation of rhinosinusitis. Most children resolve the infection spontaneously and only a small proportion develops a secondary bacterial infection. The proper choice of antibiotic therapy depends on the likely infecting pathogens, bacterial antibiotic resistance, and pharmacologic profiles of antibiotics. Amoxicillin-clavulanate is currently recommended as the empiric treatment in those requiring antimicrobial therapy. Isolation of the causative agents should be considered in those who failed the initial treatment. In addition to antibiotics, adjuvant therapies and surgery may be used in the management of acute bacterial rhinosinusitis.
authors.affiliation: Department of Pediatrics and Medicine, Georgetown University School of Medicine, Washington, DC 20016, USA. ib6@georgetown.edu
authors.forename: Itzhak
authors.initials: I
authors.lastname: Brook
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006801:Humans; D008279:Magnetic Resonance Imaging; D055624:Methicillin-Resistant Staphylococcus aureus / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D001936:Moraxella catarrhalis / Q000302:isolation & purification; D012141:Respiratory Tract Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D012220:Rhinitis / Q000150:complications / Q000175:diagnosis / Q000821:virology; D012852:Sinusitis / Q000150:complications / Q000175:diagnosis / Q000821:virology; D013211:Staphylococcus aureus / Q000302:isolation & purification; D013296:Streptococcus pneumoniae / Q000302:isolation & purification; D013297:Streptococcus pyogenes / Q000302:isolation & purification; D015163:Superinfection / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents