title: Chronic kidney disease in two coastal districts of Andhra Pradesh, India: role of drinking water.
abstract: Chronic kidney disease (CKD) has been reported in a few coastal regions of Srikakulam district and Chimakurthy mandal (~30-40 km away from the coast) in the Prakasham district of Andhra Pradesh, India. Some medical experts and the local population have apprehensions that the drinking water is the sole reason for this disease in these areas. As the source of drinking water for these two regions is only groundwater, major ions and trace elements were measured on waters from different sources to identify the causative element(s), if any. Comparison of hydrochemical data of both the areas indicates that groundwater in Srikakulam coastal region is less mineralized than that of the Prakasham region, which may be due to geological, hydrological and climatic reasons. However, the concentrations of various inorganic chemicals are within the permissible limits of drinking water. Hence, for the inorganic chemicals to cause ill health, including CKD, is unlikely or is ruled out in the study areas.
authors.affiliation: CSIR-National Geophysical Research Institute, Uppal Road, Hyderabad 500007, India. dvreddy.ngri@gmail.com
authors.forename: D V
authors.initials: DV
authors.lastname: Reddy
authors.forename: A
authors.initials: A
authors.lastname: Gunasekar
mesh_terms: D000838:Anions / Q000032:analysis; D002412:Cations / Q000032:analysis; D002852:Chromatography, Ion Exchange; D060766:Drinking Water / Q000032:analysis*; D004781:Environmental Exposure; D004784:Environmental Monitoring; D060587:Groundwater / Q000032:analysis*; D006801:Humans; D007194:India / Q000453:epidemiology; D013058:Mass Spectrometry; D051436:Renal Insufficiency, Chronic / Q000139:chemically induced* / Q000453:epidemiology; D014131:Trace Elements / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D000838:Anions; D002412:Cations; D060766:Drinking Water; D014131:Trace Elements; D014874:Water Pollutants, Chemical