title: Recent advances in biological production of 3-hydroxypropionic acid.
abstract: 3-Hydroxypropionic acid (3-HP) is a valuable platform chemical that can be produced biologically from glucose or glycerol. This review article provides an overview and the current status of microbial 3-HP production. The constraints of microbial 3-HP production and possible solutions are also described. Finally, future prospects of biological 3-HP production are discussed.
authors.affiliation: Department of Chemical and Biomolecular Engineering, Pusan National University, San 30, Jangjeon-dong, Geumjeong-gu, Busan 609-735, Republic of Korea.
authors.forename: Vinod
authors.initials: V
authors.lastname: Kumar
authors.forename: Somasundar
authors.initials: S
authors.lastname: Ashok
authors.forename: Sunghoon
authors.initials: S
authors.lastname: Park
mesh_terms: D000444:Aldehyde Dehydrogenase / Q000097:blood* / Q000737:chemistry / Q000378:metabolism; D005285:Fermentation / Q000235:genetics*; D005947:Glucose / Q000737:chemistry*; D005990:Glycerol / Q000737:chemistry*; D006801:Humans; D006836:Hydro-Lyases / Q000737:chemistry / Q000378:metabolism; D007711:Klebsiella pneumoniae / Q000235:genetics / Q000378:metabolism; D019344:Lactic Acid / Q000031:analogs & derivatives* / Q000096:biosynthesis; D011409:Propylene Glycols; D011995:Recombination, Genetic
chemical_list: D011409:Propylene Glycols; D019344:Lactic Acid; C031601:hydracrylic acid; D000444:Aldehyde Dehydrogenase; D006836:Hydro-Lyases; C020671:glycerol dehydratase; D005947:Glucose; D005990:Glycerol
keywords: 3-Hydroxypropionic acid; Aldehyde dehydrogenase; Coenzyme/vitamin B(12); Glycerol; Glycerol dehydratase; Klebsiella pneumoniae