title: Neuregulin-1 (NRG-1) and its susceptibility to schizophrenia: a case-control study and meta-analysis.
abstract: Neuregulin-1 is widely investigated due to its hypothesised association with schizophrenia. Single-nucleotide polymorphisms rs764059, rs2954041 and rs3924999 were investigated (417 patients with schizophrenia and 429 controls). We failed to demonstrate a significant association between rs2954041 and rs3924999 with schizophrenia in the three ethnic groups studied (Malay, Chinese, and Indian), while rs764059 was found to be monomorphic.
authors.affiliation: Department of Chemical Engineering, Faculty of Engineering and Science (FES), Universiti Tunku Abdul Rahman (UTAR), Jalan Genting Kelang, Setapak, 53300 Kuala Lumpur, Malaysia. hcloh@utar.edu.my
authors.forename: Han Chern
authors.initials: HC
authors.lastname: Loh
authors.forename: Pek Yee
authors.initials: PY
authors.lastname: Tang
authors.forename: Shiau Foon
authors.initials: SF
authors.lastname: Tee
authors.forename: Tze Jen
authors.initials: TJ
authors.lastname: Chow
authors.forename: Chee Yen
authors.initials: CY
authors.lastname: Choong
authors.forename: Shen Yang
authors.initials: SY
authors.lastname: Lim
authors.forename: Hoi Sen
authors.initials: HS
authors.lastname: Yong
mesh_terms: D000328:Adult; D044466:Asian People / Q000235:genetics; D016022:Case-Control Studies; D005260:Female; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006801:Humans; D008297:Male; D020890:Neuregulin-1 / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide; D012559:Schizophrenia / Q000235:genetics*; D044465:White People / Q000235:genetics
chemical_list: D020890:Neuregulin-1