title: [Computer simulation study on physiological feedback parameters during chest compression].
abstract: To have a thorough understanding of the CPR quality based on patients' various physiological states, the doctors must do something to simulate the chest compression physiological feedback parameters (CCPFP). The CCPFP simulation plays an important role in raising efficiency of CPR training and improving chest compression quality. In this study, the CCPFP, including cardiac output (CO), coronary perfusion pressure (CPP), partial pressure of End-tidal CO2 (PETCO2) and mean arterial relaxation pressure (MARP), was simulated using Charles F. Babbs' Model. Simulation results showed that the effect of compression depth upon CCPFP was important in the range of 2-6 cm, whereas compression rate had little effect on the CCPFP higher than 100/min; the thoracic factor is inversely proportional to the CCPFP with fixed compression depth and compression rate. The CCPFP simulation can be implemented at the various physiological statuses, and verified well with the animal experimental results and the clinical results.
authors.affiliation: Institute of Medical Equipment, Academy of Military Medical Science, Tianjin 300161, China.
authors.forename: Guang
authors.initials: G
authors.lastname: Zhang
authors.forename: Jiewen
authors.initials: J
authors.lastname: Zheng
authors.forename: Peng
authors.initials: P
authors.lastname: Zhao
authors.forename: Yuxiao
authors.initials: Y
authors.lastname: Wang
authors.forename: Shaowen
authors.initials: S
authors.lastname: Qian
authors.forename: Hengzhi
authors.initials: H
authors.lastname: Lu
authors.forename: Taihu
authors.initials: T
authors.lastname: Wu
mesh_terms: D001794:Blood Pressure / Q000502:physiology; D002245:Carbon Dioxide / Q000097:blood; D002302:Cardiac Output / Q000502:physiology*; D035641:Chest Wall Oscillation; D003198:Computer Simulation; D025461:Feedback, Physiological / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D010313:Partial Pressure
chemical_list: D002245:Carbon Dioxide