title: Hepatitis B and C co-infection in HIV/AIDS population in the state of Michigan.
abstract: A retrospective cohort study was conducted from 1 January 2006 to 31 December 2009 in Michigan to estimate the prevalence of HIV and hepatitis co-infection and identify associated factors. The prevalence of co-infection was 4.1% [95% confidence interval (CI) 3.8-4.5]. Multivariable logistic regression analysis revealed a significant association between co-infection and being male and: of Black race [odds ratio (OR) 2.0, 95% CI 1.2-3.6] and of Other race (OR 3.5, 95% CI 1.7-7.0) compared to Hispanic race. A significant association was found between co-infection and risk categories of blood products (OR 11.1, 95% CI 6.2-20.2), injecting drug user (IDU) (OR 3.6, 95% CI 2.7-4.8) and men who have sex with men/IDU (OR 3.4, 95% CI 2.4-4.9) in addition to two interactions; one between sex and current HIV status and the other between current HIV status and age at HIV diagnosis. Our results document the changing epidemiology of HIV-hepatitis co-infection which can guide preventive measures and interventions to reduce the prevalence of hepatitis co-infection.
authors.affiliation: Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.
authors.forename: Z A
authors.initials: ZA
authors.lastname: Butt
authors.forename: M J
authors.initials: MJ
authors.lastname: Wilkins
authors.forename: E
authors.initials: E
authors.lastname: Hamilton
authors.forename: D
authors.initials: D
authors.lastname: Todem
authors.forename: J C
authors.initials: JC
authors.lastname: Gardiner
authors.forename: M
authors.initials: M
authors.lastname: Saeed
mesh_terms: D000328:Adult; D015331:Cohort Studies; D060085:Coinfection / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006509:Hepatitis B / Q000453:epidemiology*; D006526:Hepatitis C / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008824:Michigan / Q000453:epidemiology; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D055815:Young Adult