title: Preparation and X-ray structural study of 1-arylbenziodoxolones.
abstract: Various 1-arylbenziodoxolones can be conveniently prepared from 2-iodobenzoic acid and arenes by a one-pot procedure using Oxone (2KHSO5·KHSO4·K2SO4) as an inexpensive and environmentally safe oxidant. This procedure is also applicable for the synthesis of the 7-methylbenziodoxolone ring system using 2-iodo-3-methylbenzoic acid as starting compound. Structures of four 1-arylbenziodoxolone derivatives were established by single-crystal X-ray diffraction analysis. An enhanced reactivity of 1-aryl-7-methylbenziodoxolones toward nucleophiles compared to unsubstituted 1-arylbenziodoxolones has been found.
authors.affiliation: The Siberian State Medical University, 634050 Tomsk, Russia. yusubov@mail.ru
authors.forename: Mekhman S
authors.initials: MS
authors.lastname: Yusubov
authors.forename: Roza Y
authors.initials: RY
authors.lastname: Yusubova
authors.forename: Victor N
authors.initials: VN
authors.lastname: Nemykin
authors.forename: Viktor V
authors.initials: VV
authors.lastname: Zhdankin
mesh_terms: D018360:Crystallography, X-Ray; D007463:Iodobenzoates / Q000138:chemical synthesis* / Q000737:chemistry*; D015394:Molecular Structure; D014961:X-Ray Diffraction
chemical_list: C582737:7-methylbenziodoxolone; D007463:Iodobenzoates