title: Agenesis of the ductus venosus-A case with favorable outcome after early signs of cardiac failure.
abstract: Absence of the ductus venosus (ADV) is a rare vascular anomaly. Its prognosis depends on the pathway of the umbilical flow to the systemic venous circulation, and the presence or absence of associated structural or chromosomal anomalies, sometimes resulting in hydrops fetalis. In cases with isolated ADV in the absence of associated anomalies, survival rates are as high as 85%, depending on the shunt situation. Here, we report a patient with ADV and extrahepatic umbilical vein drainage with favorable outcome after intrauterine reversal of early signs of cardiac failure. Diagnosis was made after the appearance of moderate cardiomegaly in the 25th gestational week. Thus, in the case of cardiomegaly with or without further signs of cardiac failure, ultrasound imaging of the venous duct should be considered.
authors.affiliation: Department of Pediatrics, University Hospital Carl Gustav Carus, Dresden, Germany.
authors.forename: Sigrun R
authors.initials: SR
authors.lastname: Hofmann
authors.forename: Antje
authors.initials: A
authors.lastname: Heilmann
authors.forename: Hans J
authors.initials: HJ
authors.lastname: Häusler
authors.forename: Gabriele
authors.initials: G
authors.lastname: Kamin
authors.forename: Katharina I
authors.initials: KI
authors.lastname: Nitzsche
mesh_terms: D000328:Adult; D006332:Cardiomegaly / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006333:Heart Failure / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D012075:Remission, Spontaneous; D018608:Ultrasonography, Doppler; D016216:Ultrasonography, Prenatal; D014471:Umbilical Veins / Q000002:abnormalities* / Q000000981:diagnostic imaging; D054079:Vascular Malformations / Q000150:complications / Q000000981:diagnostic imaging*