title: Hairy polyp, a clinicopathologic study of four cases.
abstract: Hairy polyps (HPs), dermoids or teratoid tumors are rare tumors of naso-oropharyngeal region which commonly present at or shortly after birth. The etiology and classification of these tumors is still debatable and categorized by different authors differently. HPs have female predominance and usually present with respiratory and feeding problems. Microscopically, the polyp is covered by skin with underlying mesenchymal core. The aim of this study is to describe the clinicopathological features of Hairy polyps on a cohort of cases. We reviewed the surgical pathology database of our institution for last 10 years and retrieved four cases of hairy polyps. The age of patients ranged from 1 month to 18 years (mean = 12 years), with a female to male ratio of 1:3. Two of our cases presented at birth and two cases in late teens. Two of the HPs were located in nasopharynx, one on soft and hard palate and one on lower lip. One case was associated with bifurcation of tongue. Size of the polyps ranged from 2.3 to 4.5 cm (mean = 3 cm). Histologically, all HPs were lined by skin and the underlying core consisted of adnexal structures, adipocytes, skeletal muscle, smooth muscle and seromucinous glands. Lymphoid aggregates, cartilage and bone were seen in one case each. Our series highlights the diverse nature of this entity in terms of age of presentation and location. HP at lower lip and associated bifurcation of tongue has not been previously reported. We observed a male predominance in contrast to the published literature. However, number of cases is too few to read a definite conclusion on this point. The etiology is still controversial and includes congenital malformation and activation of pluripotent stem cells.
authors.affiliation: Department of Pathology and Microbiology, Aga Khan University, Stadium Road, Karachi, Pakistan.
authors.forename: Muhammad Usman
authors.initials: MU
authors.lastname: Tariq
authors.forename: Nasir Ud
authors.initials: NU
authors.lastname: Din
authors.forename: Muhammad Rizwan
authors.initials: MR
authors.lastname: Bashir
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D002648:Child; D005260:Female; D006258:Head and Neck Neoplasms / Q000151:congenital / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D008048:Lip Neoplasms / Q000151:congenital / Q000473:pathology / Q000601:surgery; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000473:pathology / Q000601:surgery; D021362:Palate, Hard / Q000473:pathology; D010160:Palate, Soft / Q000473:pathology; D013724:Teratoma / Q000151:congenital / Q000473:pathology* / Q000601:surgery