title: Coenzyme Q10--a therapeutic agent.
abstract: Coenzyme Q10 (CoQ10) is critical to production of adenosine triphosphate and is an antioxidant that scavenges reactive oxygen species during oxidative stress. The use of CoQ10 in treating oxidative stress in cardiovascular diseases, diabetes, and cancer is reviewed.
authors.affiliation: Naval Medical Center, Portsmouth, VA, USA.
authors.forename: Joanna
authors.initials: J
authors.lastname: Lance
authors.forename: Shannon
authors.initials: S
authors.lastname: McCabe
authors.forename: Richard L
authors.initials: RL
authors.lastname: Clancy
authors.forename: Janet
authors.initials: J
authors.lastname: Pierce
mesh_terms: D001943:Breast Neoplasms / Q000188:drug therapy; D004347:Drug Interactions; D045222:Electron Transport Chain Complex Proteins / Q000494:pharmacology* / Q000627:therapeutic use*; D005260:Female; D006333:Heart Failure / Q000188:drug therapy; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006973:Hypertension / Q000188:drug therapy; D018384:Oxidative Stress / Q000187:drug effects* / Q000502:physiology; D014451:Ubiquinone / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D045222:Electron Transport Chain Complex Proteins; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D014451:Ubiquinone; C024989:coenzyme Q10