title: Orbital xanthogranuloma in an adult patient with xanthelasma palpebrarum and hypercholesterolemia.
abstract: A 44-year-old man with a history of hypercholesterolemia presented with eyelid lesions and a separate orbital mass. Pathology of eyelid lesions confirmed xanthelasma palpebrarum, and pathology of the orbital mass showed a non-Langerhans cell xanthogranuloma, consistent with a lesion within the spectrum of adult orbital xanthogranulomatous disorders. While xanthelasma palpebrarum is associated with increased serum lipids, adult orbital xanthogranuloma does not share a clear association. Distinct, histology-proven xanthelasma palpebrarum and orbital xanthogranuloma rarely occur together in the literature. This case further represents a unique coexistence between these 2 lesions in an adult with hypercholesterolemia.
authors.affiliation: Cleveland Clinic Foundation, Cleveland, Ohio, U.S.A.
authors.forename: Tal J
authors.initials: TJ
authors.lastname: Rubinstein
authors.forename: Milap P
authors.initials: MP
authors.lastname: Mehta
authors.forename: Lynn
authors.initials: L
authors.lastname: Schoenfield
authors.forename: Julian D
authors.initials: JD
authors.lastname: Perry
mesh_terms: D000328:Adult; D005141:Eyelid Diseases / Q000150:complications* / Q000175:diagnosis; D006099:Granuloma / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications* / Q000175:diagnosis; D008297:Male; D009916:Orbital Diseases / Q000150:complications* / Q000175:diagnosis; D014973:Xanthomatosis / Q000150:complications* / Q000175:diagnosis