title: Detection of paranasal sinus opacification with digital tomosynthesis radiography: a clinical pilot study.
abstract: OBJECTIVE
  We investigated the diagnostic accuracy of digital tomosynthesis (DT) radiography for detecting sinus opacification.
  
  
  METHODS
  For 31 adult patients with signs suggestive of sinusitis who underwent both sinus multi-detector-row computed tomography and DT, 2 readers independently assessed opacification in the maxillary, ethmoid, frontal, and sphenoid sinuses by DT and in consensus determined the presence of opacification in each sinus by multi-detector-row computed tomography as a reference. We assessed the diagnostic accuracy of DT and interreader agreement with DT using Cohen κ statistics.
  
  
  RESULTS
  For the maxillary, ethmoid, frontal, and sphenoid sinuses, opacification was identified in 81.7%, 75.9%, 59.3%, and 40.7%; the sensitivity/specificity for detecting opacification by DT were 93.9/72.7%, 79.5/71.4%, 93.8/72.7%, and 90.9/75.0% for reader 1 and 95.9/100.0%, 95.5/92.9%, 100.0/81.8%, and 81.8/75.0% for reader 2; the interreader agreement was 0.79, 0.42, 0.67, and 0.63, respectively.
  
  
  CONCLUSIONS
  Digital tomosynthesis allows relatively accurate detection of sinus opacification with substantial interreader agreement for all the sinuses except the ethmoid sinuses.
authors.affiliation: Department of Radiology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan. machira@dnh.twmu.ac.jp
authors.forename: Haruhiko
authors.initials: H
authors.lastname: Machida
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Yuhara
authors.forename: Eiko
authors.initials: E
authors.lastname: Ueno
authors.forename: Keiko
authors.initials: K
authors.lastname: Yoda
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sunose
authors.forename: Kazuyo
authors.initials: K
authors.lastname: Kita
authors.forename: Takuya
authors.initials: T
authors.lastname: Nishino
authors.forename: John M
authors.initials: JM
authors.lastname: Sabol
authors.forename: Shigeru
authors.initials: S
authors.lastname: Suzuki
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010256:Paranasal Sinuses / Q000000981:diagnostic imaging*; D010865:Pilot Projects; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D012852:Sinusitis / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000379:methods*