title: [A case of cytomegalovirus gastroduodenitis in an immunocompetent adult].
abstract: A 58-year-old male developed epigastric discomfort and high fever in 2010. Complete blood count showed leukocytosis and a small number of atypical lymphocytes. Gastric endoscopy revealed multiple gastroduodenal erosions and ulcers. Biopsy specimens were obtained and pathological examination demonstrated cytomegalic inclusion bodies. Cytomegalovirus (CMV) IgM antibody was positive and CMV DNA was detected with PCR in his blood, leading to the diagnosis of CMV gastroduodenitis. He was treated with intravenous ganciclovir and his symptoms resolved rapidly. It is recognized that CMV gastroduodenitis is extremely rare in immunocompetent hosts but sometimes shows a severe clinical course in elderly patients. The results from our present patient suggest that we should consider CMV infection in the differential diagnosis of multiple gastroduodenal erosions and ulcers. Our data also suggested that anti-CMV medications could be important treatment options for CMV gastroduodenitis, especially in elderly patients.
authors.affiliation: Department of Hematology, Kokura Memorial Hospital.
authors.forename: Takashi
authors.initials: T
authors.lastname: Onaka
authors.forename: Akihito
authors.initials: A
authors.lastname: Yonezawa
authors.forename: Kazunori
authors.initials: K
authors.lastname: Imada
mesh_terms: D000914:Antibodies, Viral / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D004382:Duodenitis / Q000188:drug therapy* / Q000821:virology; D015774:Ganciclovir / Q000627:therapeutic use*; D005756:Gastritis / Q000188:drug therapy* / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D000914:Antibodies, Viral; D015774:Ganciclovir