title: Investigation into neurogenic bladder in arthrogryposis multiplex congenita.
abstract: OBJECTIVE
  During the follow-up of children who had been diagnosed with arthrogryposis multiplex congenita (AMC), it was noted that some were experiencing dysfunctional voiding. Further investigation into these cases led to a diagnosis of neurogenic bladder. Few studies have investigated the relationship between AMC and neurogenic bladder, this being the first to describe the clinical characteristics of neurogenic bladder among these patients.
  
  
  METHODS
  A series of 26 cases were obtained from the electronic medical records of patients with AMC who were admitted to Hospital Sarah in Salvador between 1994 and 2007. The patients had all been diagnosed with neurogenic bladder through clinical symptoms, lower urinary tract exams, and urodynamic findings.
  
  
  RESULTS
  There was urinary incontinence in 21 patients (81%), and 50% had a history of urinary tract infections. Renal function was altered in 4 patients (15%) and normal in 22 (85%). In the urodynamic study, 14 patients (64%) had detrusor overactivity and 6 (27%) had underactivity.
  
  
  CONCLUSIONS
  Patients with AMC may show changes in the urinary tract, including neurogenic bladder. It is mandatory to study these symptomatic children with urinary disorders.
authors.affiliation: Center for Children's Rehabilitation of SARAH Hospital, Salvador, Brazil. Electronic address: liubiana@ig.com.br.
authors.forename: Liubiana
authors.initials: L
authors.lastname: Arantes de Araújo
authors.forename: André
authors.initials: A
authors.lastname: Ferraz de Arruda Musegante
authors.forename: Edjane
authors.initials: E
authors.lastname: de Oliveira Damasceno
authors.forename: Ubirajara
authors.initials: U
authors.lastname: Barroso
authors.forename: Roberto
authors.initials: R
authors.lastname: Badaro
mesh_terms: D001176:Arthrogryposis / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D057286:Electronic Health Records; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012189:Retrospective Studies; D001750:Urinary Bladder, Neurogenic / Q000175:diagnosis / Q000209:etiology*; D053201:Urinary Bladder, Overactive / Q000175:diagnosis / Q000209:etiology; D014549:Urinary Incontinence / Q000175:diagnosis / Q000209:etiology; D014552:Urinary Tract Infections / Q000175:diagnosis / Q000209:etiology; D014555:Urination Disorders / Q000175:diagnosis / Q000209:etiology*; D014563:Urodynamics
keywords: Arthrogryposis; Neurogenic; Urinary bladder; Urinary tract infections; Urodynamic