title: Bronchopulmonary dysplasia: new high resolution computed tomography scoring system and correlation between the high resolution computed tomography score and clinical severity.
abstract: OBJECTIVE
  To develop an high resolution computed tomography (HRCT) scoring system for the assessment of bronchopulmonary dysplasia (BPD) and determine its usefulness as compared with the chest radiographic score.
  
  
  METHODS
  Forty-two very low-birth-weight preterm infants with BPD (25 male, 17 female) were prospectively evaluated with HRCT performed at the mean age of 39.1-week postmenstrual age. Clinical severity of BPD was categorized as mild, moderate or severe. The HRCT score (0-36) of each patient was the sum of the number of bronchopulmonary segments with 1) hyperaeration and 2) parenchymal lesions (linear lesions, segmental atelectasis, consolidation and architectural distortion), respectively. We compared the HRCT scores with the chest radiographic scores (the Toce system) in terms of correlation with clinical severity.
  
  
  RESULTS
  The HRCT score had good interobserver (r = 0.969, p < 0.001) and intraobserver (r = 0.986, p < 0.001) reproducibility. The HRCT score showed better correlation (r = 0.646, p < 0.001) with the clinical severity of BPD than the chest radiographic score (r = 0.410, p = 0.007). The hyperaeration score showed better correlation (r = 0.738, p < 0.001) with the clinical severity of BPD than the parenchymal score (r = 0.523, p < 0.001).
  
  
  CONCLUSIONS
  We have developed a new HRCT scoring system for BPD based on the quantitative evaluation of pulmonary abnormalities of BPD consisting of the hyperaeration score and the parenchymal score. The HRCT score shows better correlation with the clinical severity of BPD than the radiographic score.
authors.affiliation: Department of Radiology, Seoul National University College of Medicine, Seoul 110-744, Korea.
authors.forename: Su-Mi
authors.initials: SM
authors.lastname: Shin
authors.forename: Woo Sun
authors.initials: WS
authors.lastname: Kim
authors.forename: Jung-Eun
authors.initials: JE
authors.lastname: Cheon
authors.forename: Han Suk
authors.initials: HS
authors.lastname: Kim
authors.forename: Whal
authors.initials: W
authors.lastname: Lee
authors.forename: Ah Young
authors.initials: AY
authors.lastname: Jung
authors.forename: In-One
authors.initials: IO
authors.lastname: Kim
authors.forename: Jung Hwan
authors.initials: JH
authors.lastname: Choi
mesh_terms: D001997:Bronchopulmonary Dysplasia / Q000000981:diagnostic imaging*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D008297:Male; D011446:Prospective Studies; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: Bronchopulmonary dysplasia; Chest radiography; HRCT; Preterm infants; Scoring system