title: A descriptive study of perinatal asphyxia at the University Hospital of Kinshasa (Democratic Republic of Congo).
abstract: BACKGROUND
  Perinatal asphyxia is the third cause of neonatal death after prematurity and infection.
  
  
  OBJECTIVE
  The purpose of this study was to determine the incidence, the etiology and the HIE score at the first day in term and near-term newborns with perinatal asphyxia at the University Hospital of Kinshasa.
  
  
  METHODS
  50 term and near-term neonates with perinatal asphyxia were studied prospectively after they were admitted in neonatal intensive care from November 2009 to January 2011. For each patient admitted the perinatal data were collected. Clinical assessment was performed by the Sarnat grading and the Thompson score within twenty-four hours. Medcalc® was used for statistics.
  
  
  RESULTS
  50 babies were scored. The median maternal age was 31 years. In 22% of the mothers preeclampsia was diagnosed. Urogenital infection, IUGR were other prenatal diagnoses. Median Apgar score was 4 after 1 minute, 5 after 5 minutes and 6 after 10 minutes. Sarnat grade 1 was seen in 16 patients, Sarnat grade 2 in 20 patients and grade 3 in 8. Thompson score in the first 24 hours was more than 7 in 60% of the patients. A good correlation was found between the Thompson score and the Sarnat grade (r: 0,77; p < 0,0001). 14 of the 50 babies died. Both Sarnat and Thompson score correlated significantly with mortality.
  
  
  CONCLUSIONS
  The incidence of perinatal asphyxia at the University Hospital of Kinshasa remains high and the majority of patients had a severe HIE.
authors.affiliation: Neonatal Unit, Department of Pediatrics, University Hospital of Kinshasa, Kinshasa, DR Congo.
authors.forename: Thérèse
authors.initials: T
authors.lastname: Biselele
authors.forename: Gunnar
authors.initials: G
authors.lastname: Naulaers
authors.forename: Paulo
authors.initials: P
authors.lastname: Bunga Muntu
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Nkidiaka
authors.forename: Marie
authors.initials: M
authors.lastname: Kapepela
authors.forename: Laetitia
authors.initials: L
authors.lastname: Mavinga
authors.forename: Bruno
authors.initials: B
authors.lastname: Tady
mesh_terms: D001034:Apgar Score; D001238:Asphyxia Neonatorum / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D015023:Democratic Republic of the Congo / Q000453:epidemiology; D005260:Female; D005865:Gestational Age; D006785:Hospitals, University; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000453:epidemiology / Q000209:etiology*; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008423:Maternal Age; D011247:Pregnancy; D011446:Prospective Studies; D012720:Severity of Illness Index; D050497:Stillbirth / Q000453:epidemiology
keywords: Congo; hypoxic-ischemic encephalopathy; neonate; perinatal asphyxia