title: Endovascular repair of the aortic arch in pigs by improved double-branched stent grafts.
abstract: BACKGROUND
  This study aimed to evaluate the feasibility of total endovascular repair of the aortic arch in pigs using improved integrated double-branched stent grafts.
  
  
  METHODS
  Improved self-expandable stent grafts with a main body and two integrated branches were prepared for the repair of the aortic arch in six pigs. The feasibility of using these stent grafts was evaluated with arteriography, computed tomography (CT), computed tomography angiography (CTA) and autopsy three months following the procedure.
  
  
  RESULTS
  The double-branched stent grafts were placed successfully in the aortic arch in all six pigs. All pigs survived for at least three months and their biological behaviour was normal. Arteriography, CTA and animal necropsy revealed good fixation in all cases. Aortic valve function and coronary ostia remained intact, and CT of the head did not detect any lesion of cerebral infarction.
  
  
  CONCLUSIONS
  Endovascular repair of the aortic arch with an integrated double-branched stent graft is safe and feasible in animal studies.
authors.affiliation: Department of General Surgery, Fuzhou General Hospital, Fuzhou, China.
authors.forename: C
authors.initials: C
authors.lastname: Lin
authors.forename: L
authors.initials: L
authors.lastname: Wang
authors.forename: Q
authors.initials: Q
authors.lastname: Lu
authors.forename: C
authors.initials: C
authors.lastname: Li
authors.forename: Z
authors.initials: Z
authors.lastname: Jing
mesh_terms: D000818:Animals; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging / Q000601:surgery*; D001027:Aortography; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D057510:Endovascular Procedures / Q000295:instrumentation / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D008297:Male; D061646:Operative Time; D011474:Prosthesis Design; D015607:Stents; D034421:Sus scrofa