title: Akt destabilizes p57 (Kip2) : Akt at the converging crossroad?
authors.affiliation: Division of Surgical Sciences, Department of Surgery, Duke Cancer Institute, Duke University School of Medicine, Durham, NC, USA. huiwen.lo@duke.edu
authors.forename: Hui-Wen
authors.initials: HW
authors.lastname: Lo
mesh_terms: D000818:Animals; D001943:Breast Neoplasms / Q000378:metabolism* / Q000473:pathology*; D002471:Cell Transformation, Neoplastic; D050761:Cyclin-Dependent Kinase Inhibitor p57 / Q000378:metabolism*; D005260:Female; D006801:Humans; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism*
chemical_list: D050761:Cyclin-Dependent Kinase Inhibitor p57; D051057:Proto-Oncogene Proteins c-akt; D018719:Erb-b2 Receptor Tyrosine Kinases; C508053:ERBB2 protein, human
keywords: Akt; CDK; CSN6; HER2; cancer; cell cycle; p21Cip1/WAF1; p27Kip1; p57Kip2; phosphorylation; ubiquitination