title: Carbon-dots derived from nanodiamond: photoluminescence tunable nanoparticles for cell imaging.
abstract: Water dispersible carbon-dots (CDs) with tunable photoluminescence were synthesized via one-pot hydrothermal oxidation of nanodiamond and subsequently utilized for cell imaging applications. The CDs were characterized by the following techniques including transmission electron microscopy, atomic force microscopy, Fourier transform infrared spectroscopy, UV-Visible spectroscopy, and fluorescent spectroscopy. Results showed that the size of CDs is mainly distributed at 3-7 nm. Many functional groups were introduced on the surface of CDs during hydrothermal oxidation procedure. Cell morphology observation and cell viability measurement demonstrated the good biocompatibility of CDs, suggesting their potential bioimaging applications.
authors.affiliation: Department of Chemistry and the Tsinghua Center for Frontier Polymer Research, Tsinghua University, Beijing 100084, PR China.
authors.forename: Xiaoyong
authors.initials: X
authors.lastname: Zhang
authors.forename: Shiqi
authors.initials: S
authors.lastname: Wang
authors.forename: Chongyu
authors.initials: C
authors.lastname: Zhu
authors.forename: Meiying
authors.initials: M
authors.lastname: Liu
authors.forename: Yan
authors.initials: Y
authors.lastname: Ji
authors.forename: Lin
authors.initials: L
authors.lastname: Feng
authors.forename: Lei
authors.initials: L
authors.lastname: Tao
authors.forename: Yen
authors.initials: Y
authors.lastname: Wei
mesh_terms: D000818:Animals; D002244:Carbon / Q000737:chemistry* / Q000494:pharmacology; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D051379:Mice; D008856:Microscopy, Fluorescence; D041681:NIH 3T3 Cells; D058612:Nanodiamonds / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D058612:Nanodiamonds; D002244:Carbon