title: Vessel-selective, non-contrast enhanced, time-resolved MR angiography with vessel-selective arterial spin labeling technique (CINEMA-SELECT) in intracranial arteries.
abstract: We demonstrate the feasibility of the vessel-selective, non-contrast, time-resolved magnetic resonance angiography (MRA) technique, "contrast inherent inflow enhanced multi-phase angiography combining vessel-selective arterial spin labeling technique (CINEMA-SELECT)". This sequence consists of two major techniques: pulsed star labeling of arterial regions (PULSAR) and Look-Locker sampling. We hypothesize that this technique allows selective labeling of single intracranial arteries, consisting of high-resolution four-dimensional data with a wide coverage of the brain. In this study, a new vessel-selective, time-resolved angiographic technique is demonstrated that can produce individual angiograms non-invasively by labeling the principal arterial vessels proximal to the circle of Willis. Clear vessel delineation is achieved, and the separation of the three vessels is evident in healthy volunteers. This technique could play an important role in the assessment of the structure and hemodynamics of intracranial arteries without the use of contrast agents.
authors.affiliation: Yaesu Clinic, 2-1-18 Nihonbashi, Chuou-ku, Tokyo, Japan. risen1@mac.com
authors.forename: Masanobu
authors.initials: M
authors.lastname: Nakamura
authors.forename: Masami
authors.initials: M
authors.lastname: Yoneyama
authors.forename: Takashi
authors.initials: T
authors.lastname: Tabuchi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takemura
authors.forename: Makoto
authors.initials: M
authors.lastname: Obara
authors.forename: Satoshi
authors.initials: S
authors.lastname: Tatsuno
authors.forename: Seishi
authors.initials: S
authors.lastname: Sawano
mesh_terms: D000328:Adult; D002533:Cerebral Angiography; D002536:Cerebral Arteries / Q000033:anatomy & histology*; D002560:Cerebrovascular Circulation; D005240:Feasibility Studies; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D021621:Imaging, Three-Dimensional; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D013113:Spin Labels
chemical_list: D013113:Spin Labels