title: [Immune evasion molecules of Toxoplasma gondii].
abstract: Toxoplasma gondii can live in the host for a long time relying on effective immune escape mechanisms and cause a chronic infection. Different antigenic molecules in the parasitophorous vacuole membrane, rhoptry and cytoplasm play an important role in evading the host's immune response. They can effectively help avoid the host immune response by inhibiting excessive inflammatory response and production of nitric oxide, affecting gene expression of some cytokines, depleting the specific immune substances, reducing the function of immune cells and so on. This paper summarizes the latest research advances in molecules related to the immune evasion of T. gondii.
authors.affiliation: Institute of Parasitic Diseases, Zhejiang Academy of Medical Sciences, Hangzhou 310013, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Zheng
authors.forename: Shao-Hong
authors.initials: SH
authors.lastname: Lu
mesh_terms: D000818:Animals; D006790:Host-Parasite Interactions; D006801:Humans; D057131:Immune Evasion; D014122:Toxoplasma / Q000235:genetics* / Q000276:immunology*; D014123:Toxoplasmosis / Q000276:immunology / Q000469:parasitology