title: Relationship between radiation pneumonitis and organizing pneumonia after radiotherapy for breast cancer.
abstract: BACKGROUND
  Radiation pneumonitis (RP) and organizing pneumonia (OP) are the two main types of lung damage that can occur after lung irradiation. The goal of this study was to evaluate the relationship between RP and OP after irradiation for breast cancer.
  
  
  METHODS
  Four hundred and twenty-eight patients who underwent radiotherapy for breast cancer were identified. The whole breast was irradiated with two tangential photon beams. Chest computed tomography (CT) scan were performed when patients showed any symptoms that were suspicious for pneumonitis.
  
  
  RESULTS
  Five patients (1.2%) were diagnosed with OP. All five patients showed ground glass opacities and consolidation of the border of the lesion of RP in the radiation fields. Infiltration of OP spread from the site of RP to the hilum of the ipsilateral lung. Between RP and OP, a free region space (FRS) could be detected.
  
  
  CONCLUSIONS
  OP is closely related to RP. All OP lesions developed near the site of RP.
authors.affiliation: Department of Radiology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi 470-1192, Japan. yumi-oie@fujita-hu.ac.jp
authors.forename: Yumi
authors.initials: Y
authors.lastname: Oie
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Saito
authors.forename: Masanao
authors.initials: M
authors.lastname: Kato
authors.forename: Fumitaka
authors.initials: F
authors.lastname: Ito
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Hattori
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Toyama
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Katada
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000532:radiotherapy*; D018549:Cryptogenic Organizing Pneumonia; D005260:Female; D006801:Humans; D008875:Middle Aged; D017564:Radiation Pneumonitis; D011878:Radiotherapy / Q000009:adverse effects*; D055815:Young Adult