title: Traumatic brain injury in adults.
abstract: Traumatic brain injury (TBI) remains a major public health problem. This review aims to present the principles upon which modern TBI management should be based. The early management phase aims to achieve haemodynamic stability, limit secondary insults (eg hypotension, hypoxia), obtain accurate neurological assessment and appropriately select patients for further investigation. Since 2003, the mainstay of risk stratification in the UK emergency departments has been a system of triage based on clinical assessment, which then dictates the need for a CT scan of the head. For patients with acute subdural or extradural haematomas, time from clinical deterioration to operation should be kept to a minimum, as it can affect their outcome. In addition, it is increasingly recognised that patients with severe and moderate TBI should be managed in neuroscience centres, regardless of the need for neurosurgical intervention. The monitoring and treatment of raised intracranial pressure is paramount for maintaining cerebral blood supply and oxygen delivery in patients with severe TBI. Decompressive craniectomy and therapeutic hypothermia are the subject of ongoing international multi-centre randomised trials. TBI is associated with a number of complications, some of which require specialist referral. Patients with post-concussion syndrome can be helped by supportive management in the context of a multi-disciplinary neurotrauma clinic and by patient support groups. Specialist neurorehabilitation after TBI is important for improving outcome.
authors.affiliation: Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
authors.forename: Angelos G
authors.initials: AG
authors.lastname: Kolias
authors.forename: Mathew R
authors.initials: MR
authors.lastname: Guilfoyle
authors.forename: Adel
authors.initials: A
authors.lastname: Helmy
authors.forename: Judith
authors.initials: J
authors.lastname: Allanson
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Hutchinson
mesh_terms: D001930:Brain Injuries / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D003422:Critical Care; D056424:Decompressive Craniectomy; D019468:Disease Management; D006801:Humans; D020198:Intracranial Hemorrhage, Traumatic / Q000209:etiology; D014057:Tomography, X-Ray Computed
keywords: Neurosurgery; Traumatic Brain Injury