title: Hünlich base: (re)discovery, synthesis, and structure elucidation after a century.
abstract: After almost 100 years, the structure of the product of the reaction between 2,4-diaminotoluene and formaldehyde was elucidated: derivative 3, which we call the Hünlich base, was synthesized on a multigram scale and its enantiomers were easily separated in preparative amounts. Furthermore, transformation of the NH2 groups to the corresponding bis-iodides and bis-azides is presented. The latter was also used for desymmetrization by click chemistry.
authors.affiliation: Institut für Organische Chemie, Fakultät für Chemie und Mineralogie, Universität Leipzig, Johannisallee 29, 04103 Leipzig, Germany.
authors.forename: Stephan
authors.initials: S
authors.lastname: Rigol
authors.forename: Lothar
authors.initials: L
authors.lastname: Beyer
authors.forename: Lothar
authors.initials: L
authors.lastname: Hennig
authors.forename: Joachim
authors.initials: J
authors.lastname: Sieler
authors.forename: Athanassios
authors.initials: A
authors.lastname: Giannis