title: Simultaneous determination of cyromazine and dicyclanil in animal edible tissues using UPLC-MS/MS.
abstract: Cyromazine and dicyclanil are both used as insect growth regulators. This paper describes an easy and innovative simultaneous extraction method for residues of cyromazine and dicyclanil in food of animal origin, and a confirmation procedure using UHPLC-MS/MS. The sample was extracted, deproteinised by 1% trichloracetic acid in water-acetonitrile, followed by selective defatting using hexane based on the degree of matrix complexity; cleaned-up on an mixed-mode cation exchange (MCX) cartridge; and quantified by using matrix-matched calibration. The mean recoveries were all between 62.0% and 99.2%, and the RSDs were all below 9.94%. The present method was rapid, sensitive and reliable, which was applied to the quantitative analysis of these residues in animal tissues.
authors.affiliation: Department of Veterinary Medicine, College of Animal Science, Beijing University of Agriculture, 102206 Beijing, China.
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Hou
authors.forename: Degang
authors.initials: D
authors.lastname: Zhou
authors.forename: Wenhui
authors.initials: W
authors.lastname: Huai
authors.forename: Ross C
authors.initials: RC
authors.lastname: Beier
authors.forename: Yingjian
authors.initials: Y
authors.lastname: Sun
authors.forename: Yan
authors.initials: Y
authors.lastname: Lu
authors.forename: Guojuan
authors.initials: G
authors.lastname: Wu
authors.forename: Zhiwen
authors.initials: Z
authors.lastname: Sun
authors.forename: Yongning
authors.initials: Y
authors.lastname: Wu
mesh_terms: D000818:Animals; D002138:Calibration; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D007605:Juvenile Hormones / Q000032:analysis; D057230:Limit of Detection; D008461:Meat Products / Q000032:analysis*; D010573:Pesticide Residues / Q000032:analysis*; D015203:Reproducibility of Results; D053719:Tandem Mass Spectrometry / Q000379:methods*; D014227:Triazines / Q000032:analysis*
chemical_list: D007605:Juvenile Hormones; D010573:Pesticide Residues; D014227:Triazines; C028704:cyromazine; C121718:dicyclanil