title: Tandospirone, a 5-HT1A partial agonist is effective in treating anorexia nervosa: a case series.
abstract: This case report details the therapeutic effects of tandospirone on two patients with anorexia nervosa, one with the restricting subtype (ANR), and another with the binge-eating/purging subtype (ANBP). A 22-year-old female patient with ANR and a 23-year-old female patient with ANBP were treated successfully with the 5-HT1A partial agonist tandospirone. After treatment, not only did both patients gain weight, they also showed improved scores on the Eating Disorder Examination Questionnaire. In addition, a 6-month follow-up showed maintenance of these effects. In this disorder, tandospirone may be an effective drug for long-term use with good patient compliance.
authors.affiliation: Department of Psychiatry, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Chiba, 260-8677, Japan. okitak@graduate.chiba-u.jp.
authors.forename: Kyoji
authors.initials: K
authors.lastname: Okita
authors.forename: Akihiro
authors.initials: A
authors.lastname: Shiina
authors.forename: Michiko
authors.initials: M
authors.lastname: Nakazato
authors.forename: Masaomi
authors.initials: M
authors.lastname: Iyo