title: Composition and in-vitro cytotoxic activities of the leaf essential oil of Beilschmiedia erythrophloia from Taiwan.
abstract: This study investigated the chemical composition and in-vitro cytotoxic activities of the essential oil isolated from the leaf of Beilschmiedia erythrophloia. The essential oil was isolated using hydrodistillation in a Clevenger-type apparatus, and characterized by GC-FID and GC-MS. Fifty-five compounds were identified, representing 100% of the oil. The main components identified were beta-caryophyllene (22.6%), alpha-humulene (21.9%), terpinen-4-ol (5.3%), cis-beta-ocimene (5.1%), sabinene (5.0%) and limonene (4.5%). The anticancer activities of oil were evaluated. The results showed that the oil exhibited cytotoxic activity against human oral, liver, lung, colon, melanoma, and leukemic cancer cells.
authors.affiliation: Department of Forestry, National Chung Hsing University, 250 Kuo Kuang Rd., Taichung, Taiwan 402.
authors.forename: Yu-Chang
authors.initials: YC
authors.lastname: Su
authors.forename: Chen-Lung
authors.initials: CL
authors.lastname: Ho
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000032:analysis*; D004354:Drug Screening Assays, Antitumor; D019073:HT29 Cells; D006801:Humans; D020014:K562 Cells; D019770:Lauraceae / Q000737:chemistry*; D009822:Oils, Volatile / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry; D013624:Taiwan
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D009822:Oils, Volatile