title: Progress on materials and scaffold fabrications applied to esophageal tissue engineering.
abstract: The mortality rate from esophageal disease like atresia, carcinoma, tracheoesophageal fistula, etc. is increasing rapidly all over the world. Traditional therapies such as surgery, radiotherapy or chemotherapy have been met with very limited success resulting in reduced survival rate and quality of patients' life. Tissue-engineered esophagus, a novel substitute possessing structure and function similar to native tissue, is believed to be an effective therapy and a promising replacement in the future. However, research on esophageal tissue engineering is still at an early stage. Considerable research has been focused on developing ideal scaffolds with optimal materials and methods of fabrication. This article gives a review of materials and scaffold fabrications currently applied in esophageal tissue engineering research.
authors.affiliation: School of Medicine, Ningbo University, Ningbo 315211, China.
authors.forename: Qiuxiang
authors.initials: Q
authors.lastname: Shen
authors.forename: Peina
authors.initials: P
authors.lastname: Shi
authors.forename: Mongna
authors.initials: M
authors.lastname: Gao
authors.forename: Xuechan
authors.initials: X
authors.lastname: Yu
authors.forename: Yuxin
authors.initials: Y
authors.lastname: Liu
authors.forename: Ling
authors.initials: L
authors.lastname: Luo
authors.forename: Yabin
authors.initials: Y
authors.lastname: Zhu
mesh_terms: D001672:Biocompatible Materials / Q000494:pharmacology*; D004947:Esophagus / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D009132:Muscles / Q000187:drug effects / Q000502:physiology; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials