title: Cu(OTf)2 catalysed [6+2] cycloaddition reaction for the synthesis of highly substituted pyrrolo[1,2-a]indoles: rapid construction of the yuremamine core.
abstract: Lewis acid catalysed [6+2] cycloaddition reaction for the synthesis of pyrrolo[1,2-a]indoles generating three contiguous stereocenters in a highly regio- and diastereoselective manner has been developed and further applied for the construction of the fully functionalized tricyclic core of yuremamine.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208016, India. ddethe@iitk.ac.in
authors.forename: Dattatraya H
authors.initials: DH
authors.lastname: Dethe
authors.forename: Raghavender
authors.initials: R
authors.lastname: Boda
authors.forename: Saikat
authors.initials: S
authors.lastname: Das
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis / Q000737:chemistry; D002384:Catalysis; D056831:Coordination Complexes / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D061565:Cycloaddition Reaction; D007211:Indoles / Q000138:chemical synthesis / Q000737:chemistry*; D058116:Lewis Acids / Q000737:chemistry; D010936:Plant Extracts / Q000737:chemistry*; D011758:Pyrroles / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D056831:Coordination Complexes; D007211:Indoles; D058116:Lewis Acids; D010936:Plant Extracts; D011758:Pyrroles; C507332:Yuremamine; D003300:Copper