title: Determining research priorities for clinician-initiated trials in infectious diseases.
abstract: OBJECTIVE
  To determine research priorities of infectious diseases physicians for clinician-initiated randomised controlled trials (RCTs).
  
  
  METHODS
  Online survey of infectious diseases physicians in Australia and New Zealand.
  
  
  METHODS
  Research priorities for, and perceived barriers to, clinician-initiated RCTs.
  
  
  RESULTS
  122/550 infectious diseases physicians (22%) responded to the survey. The five highest ranked proposals for clinician-initiated RCTs were in the areas of prosthetic joint infections, septic arthritis and osteomyelitis of native joints, Staphylococcus aureus bloodstream infections, diabetic foot infections and the treatment of serious multiresistant, gram-negative bacterial infections. Lack of funding was the most important perceived barrier to participation in clinician-initiated RCTs.
  
  
  CONCLUSIONS
  The research focus of infectious diseases physicians - optimal treatment of commonly encountered serious infections - highlights a lack of well conducted RCTs in this area.
authors.affiliation: Centre for Clinical Research, University of Queensland, Brisbane, QLD, Australia. david.antibiotics@gmail.com
authors.forename: David L
authors.initials: DL
authors.lastname: Paterson
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D001291:Attitude of Health Personnel; D001315:Australia; D003140:Communicable Disease Control / Q000379:methods*; D003141:Communicable Diseases / Q000188:drug therapy*; D005260:Female; D019538:Health Care Surveys; D006801:Humans; D008297:Male; D020380:Needs Assessment; D009520:New Zealand; D010818:Practice Patterns, Physicians'; D016032:Randomized Controlled Trials as Topic; D012106:Research / Q000706:statistics & numerical data*; D011795:Surveys and Questionnaires
chemical_list: D000890:Anti-Infective Agents