title: Is there any need for a shunt in the treatment of tetralogy of Fallot with one source of pulmonary blood flow?
abstract: OBJECTIVE
  In symptomatic patients, performing a primary repair of tetralogy of Fallot (TOF), irrespective of age or placing a shunt, remains controversial. The aim of the study was to analyse the policy of primary correction.
  
  
  METHODS
  Between May 2005 and May 2012, a total of 87 consecutive patients with TOF, younger than 6 months of age, underwent primary correction. All patients had one source of pulmonary blood flow, with or without a patent ductus arteriosus. The median age at surgery was 106 ± 52.3 days (8-180 days). Twelve patients (13.8%) were newborns. Two groups were analysed: group I, patients <1 month of age; group II, patients between 2-6 months of age.
  
  
  RESULTS
  There was no early or late death at 7 years of follow-up. There was no difference in bypass time or hospital stay between the two groups, but the Aristotle comprehensive score (P < 0.0001), ICU stay (P = 0.030) and the length of ventilation (P = 0.014) were significantly different. Freedom from reoperation was 87.3 ± 4.3% and freedom from reintervention was 85.9 ± 4.2% at 7 years, with no difference between the two groups. Neurological development was normal in all patients, but 1 patient in Group II had cerebral seizures and showed developmental delay. Growth was adequate in all patients, except those with additional severe non-cardiac malformations that caused developmental delay. Eighty-five per cent of the patients were without cardiac medication.
  
  
  CONCLUSIONS
  Even in symptomatic neonates and infants <6 months of age, primary repair of TOF can be performed safely and effectively. One hundred per cent survival at 7 years suggests that early primary repair causes no increase in mortality in the modern era. Shunting is not necessary, even in symptomatic newborns, thus avoiding the risk of shunt-related complications and repeated hospital stays associated with a staged approach.
authors.affiliation: Department of Paediatric Cardio-Thoracic Surgery, German Pediatric Heart Center ('Deutsches Kinderherzzentrum'), Asklepios Clinic, Sankt Augustin, Germany.
authors.forename: Claudia
authors.initials: C
authors.lastname: Arenz
authors.forename: Alke
authors.initials: A
authors.lastname: Laumeier
authors.forename: Stefanie
authors.initials: S
authors.lastname: Lütter
authors.forename: Hedwig Christine
authors.initials: HC
authors.lastname: Blaschczok
authors.forename: Nicodème
authors.initials: N
authors.lastname: Sinzobahamvya
authors.forename: Christoph
authors.initials: C
authors.lastname: Haun
authors.forename: Boulos
authors.initials: B
authors.lastname: Asfour
authors.forename: Viktor
authors.initials: V
authors.lastname: Hraska
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D053208:Kaplan-Meier Estimate; D008297:Male; D011183:Postoperative Complications; D011664:Pulmonary Valve / Q000601:surgery; D011665:Pulmonary Valve Insufficiency; D013771:Tetralogy of Fallot / Q000601:surgery*; D016896:Treatment Outcome
keywords: Neonate; Outcome; Pulmonary valve; Shunt; Tetralogy of Fallot