title: Two new types of bisindole alkaloid from Trigonostemon lutescens.
abstract: Six unprecedented bisindole alkaloids, trigolutesins A and B (1-2) with a unique polycyclic skeleton and trigolutes A-D (3-6) with another polycyclic skeleton, were isolated from the twigs of Trigonostemon lutescens. Their structures and relative configurations were elucidated by spectroscopic data and single-crystal X-ray diffraction crystallography. Trigolutesin A (1) showed weak AChE inhibitory activity.
authors.affiliation: Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agriculture Sciences, Haikou 571101, PR China.
authors.forename: Shan-Shan
authors.initials: SS
authors.lastname: Ma
authors.forename: Wen-Li
authors.initials: WL
authors.lastname: Mei
authors.forename: Zhi-Kai
authors.initials: ZK
authors.lastname: Guo
authors.forename: Shou-Bai
authors.initials: SB
authors.lastname: Liu
authors.forename: You-Xing
authors.initials: YX
authors.lastname: Zhao
authors.forename: De-Lan
authors.initials: DL
authors.lastname: Yang
authors.forename: Yan-Bo
authors.initials: YB
authors.lastname: Zeng
authors.forename: Bei
authors.initials: B
authors.lastname: Jiang
authors.forename: Hao-Fu
authors.initials: HF
authors.lastname: Dai
mesh_terms: D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018360:Crystallography, X-Ray; D019665:Euphorbiaceae / Q000737:chemistry*; D026121:Indole Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008968:Molecular Conformation; D015394:Molecular Structure
chemical_list: D002800:Cholinesterase Inhibitors; D026121:Indole Alkaloids; C583471:trigolutesin A