title: Malaria transmission pattern in an area selected for clinical trials in the sudanian area of senegal (west Africa).
abstract: Malaria transmission pattern was studied in 3 villages (Toubanding, Daga Ndoup, and Keur Samba Guèye) situated within an area selected for clinical trials. The study was conducted in the rainy season from July to December 2011. The main objective of this work was to gather baseline data on malaria transmission intensity and other entomological parameters before the advent of clinical trials. Mosquitoes were collected by Human-Landing Collections (HLCs) and by pyrethrum spray catches (PSCs). Five anopheline species were collected, namely, An. arabiensis, An. gambiae, An. funestus, An. pharoensis, and An. rufipes, giving a heterogeneous distribution within the study area. The populations dynamics of the vectors varied temporarily in each village depending on the pattern of the rainy season. Transmission intensity estimated by the entomological inoculation rate (EIR) was measured in each of the three villages with the variations linked to the microecological differences between the villages. Measurements were calculated for August, September, and October and were found to vary between 4 and 30 infected bites per person over the study period with a peak intensity observed in September. These results indicate that epidemiological field trials on malaria could be conducted in this area on the basis of the differences observed with transmission intensity, micro-ecological variations, and the objectives of the trials.
authors.affiliation: Unité d'Entomologie Médicale, Institut Pasteur de Dakar, BP 220, Dakar, Senegal ; Laboratoire d'Ecologie Vectorielle et Parasitaire, Département de Biologie Animale, Faculté des Sciences et Techniques, Université Cheikh Anta Diop de Dakar, BP 5005, Dakar, Senegal.
authors.forename: El Hadji Amadou
authors.initials: el HA
authors.lastname: Niang
authors.forename: Aissatou
authors.initials: A
authors.lastname: Touré
authors.forename: El Hadji Malick
authors.initials: el HM
authors.lastname: Ngom
authors.forename: Lassana
authors.initials: L
authors.lastname: Konaté
authors.forename: Ousmane
authors.initials: O
authors.lastname: Faye
authors.forename: Mawlouth
authors.initials: M
authors.lastname: Diallo
authors.forename: Ibrahima
authors.initials: I
authors.lastname: Dia