title: Diagnostic value of MRI for odontogenic tumours.
abstract: OBJECTIVE
  To evaluate the diagnostic value of MRI for odontogenic tumours.
  
  
  METHODS
  51 patients with odontogenic tumours were subjected to pre-operative MRI examinations. For tumours with liquid components, i.e. ameloblastomas and keratocystic odontogenic tumours (KCOTs), the signal intensity (SI) uniformity of their cystic components (UΣ) was calculated and then their UΣ values were compared. For tumours with solid components that had been examined using dynamic contrast-enhanced MRI (DCE-MRI), their CImax (maximum contrast index), Tmax (the time when CImax occurred), CIpeak (CImax × 0.90), Tpeak (the time when CIpeak occurred) and CI300 (i.e. the CI observed at 300 s after contrast medium injection) values were determined from CI curves. We then classified the odontogenic tumours according to their DCE-MRI parameters.
  
  
  RESULTS
  Significant differences between the UΣ values of the ameloblastomas and KCOT were observed on T1 weighted images, T2 weighted images and short TI inversion recovery images. Depending on their DCE-MRI parameters, we classified the odontogenic tumours into the following five types: Type A, CIpeak > 2.0 and Tpeak < 200 s; Type B, CIpeak < 2.0 and Tpeak < 200 s; Type C, CI300 > 2.0 and Tmax < 600 s; Type D, CI300 > 2.0 and Tmax > 600 s; Type E, CI300 < 2.0 and Tmax > 600 s.
  
  
  CONCLUSIONS
  Cystic component SI uniformity was found to be useful for differentiating between ameloblastomas and KCOT. However, the DCE-MRI parameters of odontogenic tumours, except for odontogenic fibromas and odontogenic myxomas, contributed little to their differential diagnosis.
authors.affiliation: Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama City, Okayama, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Fujita
authors.forename: H
authors.initials: H
authors.lastname: Matsuzaki
authors.forename: Y
authors.initials: Y
authors.lastname: Yanagi
authors.forename: M
authors.initials: M
authors.lastname: Hara
authors.forename: N
authors.initials: N
authors.lastname: Katase
authors.forename: M
authors.initials: M
authors.lastname: Hisatomi
authors.forename: T
authors.initials: T
authors.lastname: Unetsubo
authors.forename: H
authors.initials: H
authors.lastname: Konouchi
authors.forename: H
authors.initials: H
authors.lastname: Nagatsuka
authors.forename: J-I
authors.initials: JI
authors.lastname: Asaumi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000564:Ameloblastoma / Q000473:pathology; D002648:Child; D003287:Contrast Media; D020420:Cyst Fluid; D003937:Diagnosis, Differential; D005260:Female; D005350:Fibroma / Q000473:pathology; D006801:Humans; D007573:Jaw Neoplasms / Q000145:classification / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D009232:Myxoma / Q000473:pathology; D009808:Odontogenic Tumors / Q000145:classification / Q000473:pathology*; D012372:ROC Curve; D018709:Statistics, Nonparametric; D055815:Young Adult
chemical_list: D003287:Contrast Media