title: Azo-polysiloxanes as new supports for cell cultures.
abstract: The paper introduces a new class of materials with azo-polysiloxanic structure bearing the property to generate nano-structured surfaces by laser irradiation. The ability to modulate the optical response of the film, through a modification of the polymer chemical structure, has been investigated. The azo-materials were tested for their ability to support cell adhesion and growth, with very promising results. A future use of these materials as growth support in cell cultures is of great interest, due to an easy, one step-method to generate the surface relief grating and to the possibility to introduce a large range of chemical modifications due to the presence of the chlorobenzyl groups in the polymeric side-chain.
authors.affiliation: Gheorghe Asachi Technical University of Iasi, Department of Natural and Synthetic Polymers, Prof. Dimitrie, Mangeron Street, 73, 700050-Iasi, Romania. nhurduc@ch.tuiasi.ro
authors.forename: Nicolae
authors.initials: N
authors.lastname: Hurduc
authors.forename: Alina
authors.initials: A
authors.lastname: Macovei
authors.forename: Cristina
authors.initials: C
authors.lastname: Paius
authors.forename: Alina
authors.initials: A
authors.lastname: Raicu
authors.forename: Ioana
authors.initials: I
authors.lastname: Moleavin
authors.forename: Norica
authors.initials: N
authors.lastname: Branza-Nichita
authors.forename: Matthieu
authors.initials: M
authors.lastname: Hamel
authors.forename: Licinio
authors.initials: L
authors.lastname: Rocha
mesh_terms: D001391:Azo Compounds / Q000737:chemistry / Q000494:pharmacology*; D018929:Cell Culture Techniques / Q000379:methods*; D045744:Cell Line, Tumor; D002478:Cells, Cultured; D005455:Fluorescent Antibody Technique; D006801:Humans; D018625:Microscopy, Atomic Force; D012833:Siloxanes / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D001391:Azo Compounds; D012833:Siloxanes