title: Use of a vessel sealing system versus conventional electrocautery for lung parenchymal resection: a comparison of the clinicopathological outcomes in porcine lungs.
abstract: OBJECTIVE
  LigaSure, a vessel sealing system, has been shown to have excellent hemostatic properties; however, its use for lung parenchymal resection has been limited. We herein examined the hemostatic properties and potential for inducing histological lung injury of the LigaSure system in non-anatomic pulmonary resection to estimate the feasibility of its clinical application.
  
  
  METHODS
  Non-anatomic pulmonary wedge resections of the right cranial, middle, and caudal lobes were performed in four pigs using the LigaSure system (Group A) or electrocautery (Group B). In each resection, the resection time, blood loss, and weight of the resected lung were measured. The thermal effect on the lung tissue was examined by means of intraoperative thermography and histology.
  
  
  RESULTS
  A total of 12 lung wedge resections were performed in each group. For an equivalent length of operation and weight of the resected lung parenchyma, Group A showed significantly lower blood loss and lower maximum and minimum temperatures of the lung tissue, as assessed by thermography, than Group B. The degree of thermal injury as estimated by a histological examination was lower in Group A than in Group B.
  
  
  CONCLUSIONS
  Our study suggests that the LigaSure system may be superior to conventional electrocautery, indicating its clinical usefulness for non-anatomic pulmonary resection.
authors.affiliation: Department of Thoracic Surgery, Okayama University Hospital, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan, sei1675sugi@yahoo.co.jp.
authors.forename: Seiichiro
authors.initials: S
authors.lastname: Sugimoto
authors.forename: Shinichi
authors.initials: S
authors.lastname: Toyooka
authors.forename: Norichika
authors.initials: N
authors.lastname: Iga
authors.forename: Masashi
authors.initials: M
authors.lastname: Furukawa
authors.forename: Ryujiro
authors.initials: R
authors.lastname: Sugimoto
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Shien
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Nishikawa
authors.forename: Junichi
authors.initials: J
authors.lastname: Soh
authors.forename: Masaomi
authors.initials: M
authors.lastname: Yamane
authors.forename: Takahiro
authors.initials: T
authors.lastname: Oto
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Miyoshi
mesh_terms: D000818:Animals; D016063:Blood Loss, Surgical / Q000517:prevention & control; D004564:Electrocoagulation / Q000009:adverse effects; D005240:Feasibility Studies; D006488:Hemostasis, Surgical / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D055370:Lung Injury / Q000209:etiology / Q000517:prevention & control; D011013:Pneumonectomy / Q000379:methods*; D013552:Swine; D016896:Treatment Outcome