title: Single tracking location methods suppress speckle noise in shear wave velocity estimation.
abstract: In ultrasound-based elastography methods, the estimation of shear wave velocity typically involves the tracking of speckle motion due to an applied force. The errors in the estimates of tissue displacement, and thus shear wave velocity, are generally attributed to electronic noise and decorrelation due to physical processes. We present our preliminary findings on another source of error, namely, speckle-induced bias in phase estimation. We find that methods that involve tracking in a single location, as opposed to multiple locations, are less sensitive to this source of error since the measurement is differential in nature and cancels out speckle-induced phase errors.
authors.affiliation: Department of Biomedical Engineering, University of Rochester, Rochester, NY 14627, USA. etana.elegbe@rochester.edu
authors.forename: Etana C
authors.initials: EC
authors.lastname: Elegbe
authors.forename: Stephen A
authors.initials: SA
authors.lastname: McAleavey
mesh_terms: D000818:Animals; D015982:Bias; D003198:Computer Simulation; D055119:Elastic Modulus; D054459:Elasticity Imaging Techniques / Q000379:methods*; D004560:Electricity; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008099:Liver / Q000000981:diagnostic imaging; D008954:Models, Biological; D009038:Motion; D019047:Phantoms, Imaging; D012815:Signal Processing, Computer-Assisted; D059629:Signal-To-Noise Ratio; D013552:Swine