title: New solid-state chemistry technologies to bring better drugs to market: knowledge-based decision making.
abstract: Modern drug development demands constant deployment of more effective technologies to mitigate the high cost of bringing new drugs to market. In addition to cost savings, new technologies can improve all aspects of pharmaceutical development. New technologies developed at SSCI, Inc. include solid form development of an active pharmaceutical ingredients. (APIs) are PatternMatch software and capillary-based crystallisation techniques that not only allow for fast and effective solid form screening, but also extract maximum property information from the routine screening data that is generally available. These new technologies offer knowledge-based decision making during solid form development of APIs and result in more developable API solid forms.
authors.affiliation: SSCI, Inc., 3065 Kent Avenue West Lafayette, IN 47906, USA. apark@ssci-inc.com.
authors.forename: Aeri
authors.initials: A
authors.lastname: Park
authors.forename: Leonard J
authors.initials: LJ
authors.lastname: Chyall
authors.forename: Jeanette
authors.initials: J
authors.lastname: Dunlap
authors.forename: Christine
authors.initials: C
authors.lastname: Schertz
authors.forename: David
authors.initials: D
authors.lastname: Jonaitis
authors.forename: Barbara C
authors.initials: BC
authors.lastname: Stahly
authors.forename: Simon
authors.initials: S
authors.lastname: Bates
authors.forename: Rex
authors.initials: R
authors.lastname: Shipplett
authors.forename: Scott
authors.initials: S
authors.lastname: Childs