title: Serial MRI findings in brain anoxia leading to Lance-Adams syndrome: a case report.
abstract: Although in literature almost 150 patients with Lance-Adams Syndrome (LAS) have been reported, neuroradiological evaluations were often performed in late stages and there is no serial study evaluating LAS from early stages. We herein report a serial neuroimaging study demonstrating early and transient involvement of cerebellum and thalami in a LAS patient. We may hypothesize that a transient cerebral hypoxia provoked a permanent synaptic rearrangements of the neuronal networks involved in the pathogenesis of post-hypoxic myoclonus in our patient.
authors.affiliation: Institute of Neurology, Magna Græcia University, Catanzaro, Italy.
authors.forename: Edoardo
authors.initials: E
authors.lastname: Ferlazzo
authors.forename: Sara
authors.initials: S
authors.lastname: Gasparini
authors.forename: Vittoria
authors.initials: V
authors.lastname: Cianci
authors.forename: Andrea
authors.initials: A
authors.lastname: Cherubini
authors.forename: Umberto
authors.initials: U
authors.lastname: Aguglia
mesh_terms: D000328:Adult; D002531:Cerebellum / Q000473:pathology*; D005260:Female; D006801:Humans; D002534:Hypoxia, Brain / Q000150:complications*; D008279:Magnetic Resonance Imaging; D009207:Myoclonus / Q000175:diagnosis* / Q000209:etiology*; D013577:Syndrome; D013788:Thalamus / Q000473:pathology*