title: Nucleic acid lateral flow tests for molecular diagnosis: an update.
abstract: Lateral flow tests for molecular diagnosis have enormous potential in the fields of clinical practice, food safety, genotyping and environmental contamination. This paper describes the basic features of nucleic acid lateral flow (NALF) tests and some recent evolutions in this domain. The paper intentionally does not report on the accuracy of NALF tests, a largely under-investigated aspect of these tests. As for lateral flow immunoassays, NALF tests are intended to simplify detection of an analyte. Thus, designing NALF tests that are less dependent on or independent of sophisticated equipment remains a major challenge.
authors.affiliation: Institute of Tropical Medicine, Department of Parasitology, Parasite Diagnostics Unit, Nationalestraat 155, B-2000 Antwerpen, Belgium +32 3 247 63 71 ; +32 3 247 63 73 ; pbuscher@itg.be.
authors.forename: Philippe
authors.initials: P
authors.lastname: Büscher