title: Staging of hepatic fibrosis: comparison of magnetic resonance elastography and shear wave elastography in the same individuals.
abstract: OBJECTIVE
  To cross-validate liver stiffness (LS) measured on shear wave elastography (SWE) and on magnetic resonance elastography (MRE) in the same individuals.
  
  
  METHODS
  We included 94 liver transplantation (LT) recipients and 114 liver donors who underwent either MRE or SWE before surgery or biopsy. We determined the technical success rates and the incidence of unreliable LS measurements (LSM) of SWE and MRE. Among the 69 patients who underwent both MRE and SWE, the median and coefficient of variation (CV) of the LSM from each examination were compared and correlated. Areas under the receiver operating characteristic curve in both examinations were calculated in order to exclude the presence of hepatic fibrosis (HF).
  
  
  RESULTS
  The technical success rates of MRE and SWE were 96.4% and 92.2%, respectively (p = 0.17), and all of the technical failures occurred in LT recipients. SWE showed 13.1% unreliable LSM, whereas MRE showed no such case (p < 0.05). There was moderate correlation in the LSM in both examinations (r = 0.67). SWE showed a significantly larger median LSM and CV than MRE. Both examinations showed similar diagnostic performance for excluding HF (Az; 0.989, 1.000, respectively).
  
  
  CONCLUSIONS
  MRE and SWE show moderate correlation in their LSMs, although SWE shows higher incidence of unreliable LSMs in cirrhotic liver.
authors.affiliation: Department of Radiology, Seoul National University College of Medicine, Seoul 110-744, Korea.
authors.forename: Jeong Hee
authors.initials: JH
authors.lastname: Yoon
authors.forename: Jeong Min
authors.initials: JM
authors.lastname: Lee
authors.forename: Hyun Sik
authors.initials: HS
authors.lastname: Woo
authors.forename: Mi Hye
authors.initials: MH
authors.lastname: Yu
authors.forename: Ijin
authors.initials: I
authors.lastname: Joo
authors.forename: Eun Sun
authors.initials: ES
authors.lastname: Lee
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Sohn
authors.forename: Kyung Boon
authors.initials: KB
authors.lastname: Lee
authors.forename: Joon Koo
authors.initials: JK
authors.lastname: Han
authors.forename: Byung Ihn
authors.initials: BI
authors.lastname: Choi
mesh_terms: D000293:Adolescent; D000328:Adult; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D016014:Linear Models; D008103:Liver Cirrhosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D016031:Liver Transplantation; D019520:Living Donors; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012372:ROC Curve; D012680:Sensitivity and Specificity
keywords: Cross-validation; Elastography; Hepatic fibrosis; Magnetic resonance elastography; Shear wave elastography; Ultrasound-based elastography