title: [Clinical and pathogenetic aspects of the chronic occupational intoxication with fluorine compounds in modern reality].
abstract: Multi-year follow-up of 358 workers of aluminum pot rooms, including 165 individuals suffering from fluorosis, has shown significant changes in the clinical picture of the chronic occupational fluorine intoxication, developed under modern conditions of production, at lower concentrations of fluorine compounds in the air of working area. In this connection, the pathology of the musculoskeletal system plays the dominating role in this clinical picture and has the large variability of combinations of the individual sections destructions of the bone tissue. The main criterion to establish the phase of the disease is still the number and severity of the signs of this destruction. The visceral pathology in contemporary production circumstances is registered with less frequency and loses a number of the previously described clinical manifestations, however, is still of some importance to identify the early signs of the disease and to prevent the dental fluorosis on time.
authors.forename: N A
authors.initials: NA
authors.lastname: Roslaia
authors.forename: E I
authors.initials: EI
authors.lastname: Likhacheva
authors.forename: I E
authors.initials: IE
authors.lastname: Oranskiĭ
authors.forename: V A
authors.initials: VA
authors.lastname: Odinokaia
authors.forename: É G
authors.initials: ÉG
authors.lastname: Plotko
authors.forename: E P
authors.initials: EP
authors.lastname: Zhovtiak
authors.forename: A A
authors.initials: AA
authors.lastname: Fedorov
authors.forename: E V
authors.initials: EV
authors.lastname: Riabko
mesh_terms: D000328:Adult; D000395:Air Pollutants, Occupational / Q000633:toxicity; D000535:Aluminum; D001847:Bone Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D002617:Chemical Industry; D042241:Early Diagnosis; D004572:Electrolysis / Q000009:adverse effects / Q000379:methods; D005260:Female; D005458:Fluoride Poisoning / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D017611:Fluorine Compounds / Q000633:toxicity*; D009050:Fluorosis, Dental / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D016273:Occupational Exposure / Q000517:prevention & control*; D012189:Retrospective Studies; D012426:Russia / Q000453:epidemiology; D012720:Severity of Illness Index
chemical_list: D000395:Air Pollutants, Occupational; D017611:Fluorine Compounds; D000535:Aluminum