title: Association of cytomegalovirus with idiopathic chronic anterior uveitis with ocular hypertension in Korean patients.
abstract: OBJECTIVE
  To investigate the association between cytomegalovirus and idiopathic chronic recurrent anterior uveitis with ocular hypertension.
  
  
  METHODS
  Medical records of 9 consecutive immunocompetent Korean patients with chronic recurrent anterior uveitis and ocular hypertension were retrospectively reviewed. Nested polymerase chain reaction was performed on aqueous humor samples for the herpes family, including cytomegalovirus, varicella zoster virus, herpes simplex virus, and Epstein-Barr virus.
  
  
  RESULTS
  In 7 (77.8%) of 9 patients, aqueous samples were culture-positive for cytomegalovirus (n = 6), Epstein-Barr virus (n = 2), and/or varicella zoster virus (n = 2). Two patients with cytomegalovirus had corneal endotheliitis, and 2 patients with varicella zoster virus had sectoral iris atrophy.
  
  
  CONCLUSIONS
  Cytomegalovirus is the most common cause of idiopathic chronic unilateral anterior uveitis with ocular hypertension in immunocompetent Korean patients. The authors suggest that performing polymerase chain reaction on aqueous samples is useful in diagnosing cytomegalovirus in these patients.
authors.affiliation: Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.
authors.forename: Sung Wook
authors.initials: SW
authors.lastname: Park
authors.forename: Hyeong Gon
authors.initials: HG
authors.lastname: Yu
mesh_terms: D003587:Cytomegalovirus / Q000235:genetics*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000453:epidemiology / Q000821:virology; D004279:DNA, Viral / Q000032:analysis*; D015828:Eye Infections, Viral / Q000150:complications / Q000453:epidemiology / Q000821:virology; D006801:Humans; D015994:Incidence; D009798:Ocular Hypertension / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D014606:Uveitis, Anterior / Q000150:complications / Q000453:epidemiology / Q000821:virology
chemical_list: D004279:DNA, Viral