title: Materials characterization and mechanobiology of the eye.
abstract: The eye responds to a great deal of internal and external stimuli throughout its normal function. Due to this, a mechanical or chemical analysis alone is insufficient. A systematic materials characterization is needed. A mechanobiological approach is required for a full understanding of the unique properties and function of the eye. This review compiles the mechanical properties of select eye components, summarizes mechanical and chemical testing platforms, and overviews modeling approaches. Analysis is done across studies, experimental methods, and between species in order to summarize what is known about the mechanobiology of the eye. Several opportunities for future research are identified.
authors.affiliation: Department of Materials Science and Engineering, North Carolina State University, Raleigh, NC 27695, USA.
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Hugar
authors.forename: Albena
authors.initials: A
authors.lastname: Ivanisevic
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology*; D001696:Biomechanical Phenomena / Q000187:drug effects / Q000502:physiology; D003198:Computer Simulation; D005123:Eye / Q000033:anatomy & histology / Q000187:drug effects*; D006801:Humans; D008422:Materials Testing
chemical_list: D001672:Biocompatible Materials