title: Recent advances in marine drug research.
abstract: Structures and properties of promising marine anti-cancer, anti-inflammation and anti-infectious (HIV, HSV, malaria, leishmania) compounds reported during 2008-2011 are discussed. Wherever possible, attempts have also been made to highlight their possible biogenesis or structure-activity relationships (SAR). Since the stress is on identifying and short-listing potential drug molecules, this review is restricted to only those compounds exhibiting promising in vitro activity, the arbitrary cut off being IC50<15 μM, reported during the above period.
authors.affiliation: CSIR-National Institute of Oceanography Regional Centre, Dr Salim Ali road, Cochin 682018, India.
authors.forename: Saradavey
authors.initials: S
authors.lastname: Vinothkumar
authors.forename: P S
authors.initials: PS
authors.lastname: Parameswaran
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry; D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D059001:Aquatic Organisms / Q000737:chemistry*; D000458:Cyanobacteria / Q000737:chemistry; D006801:Humans; D051379:Mice; D011161:Porifera / Q000737:chemistry
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents
keywords: Alkaloid; Anti-cancer; Anti-infectious; Anti-inflammation; Depsipeptide; Lipopeptide; Sponge