title: Effects of omeprazole over voice quality in muscle tension dysphonia patients with laryngopharyngeal reflux.
abstract: BACKGROUND
  Laryngopharyngeal reflux (LPR) is the backflow of stomach contents above upper esophageal sphincter, into the pharynx, larynx, and upper aerodigestive system.
  
  
  OBJECTIVE
  In this study, effects of omeprazole over voice quality in muscle tension dysphonia with laryngopharyngeal reflux was ınvestigated.
  
  
  METHODS
  Nine patients, 7 males and 2 females, aged between 27-43 (mean age:31) were included to this study. The diagnosis of muscle tension dysphonia with LPR was established by video laryngoscopy, rigid scope 70º. The laryngeal changes related with LPR were evaluated according to Reflux Finding Score. The patients received omeprazole 20 mg twice a day for a period of 6 months. None of the patients received voice therapy. Vocal hygiene guidelines were also explained to the patients. Objective and subjective voice parameters (Jitter, shimmer, NHR, Voice Handicap Index, and Auditive analysis; Roughness, breathiness, and hoarseness) were evaluated in this study.
  
  
  RESULTS
  After treatment with omeprazol, all the parameters showed an improvement in voice quality, but only VHI (P = 0) and shimmer (P = 0,018) are statistically significant.
  
  
  CONCLUSIONS
  For FD patients with LPR condition, we highly recommend that LPR treatment should be part of the treatment plan.
authors.affiliation: Izmir Teaching and Research Hospital, Department of Otolaryngology Head and Neck Surgery, Izmir, Turkey.
authors.forename: Tolga
authors.initials: T
authors.lastname: Kandogan
authors.forename: Gökce
authors.initials: G
authors.lastname: Aksoy
authors.forename: Abdullah
authors.initials: A
authors.lastname: Dalgic
keywords: Dysphonia; Stomach, Proton Pump Inhibitors