title: Ethyl 4-(5-bromo-1H-indol-3-yl)-2,6,6-trimethyl-5-oxo-1,4,5,6,7,8-hexa-hydro-quinoline-3-carboxyl-ate.
abstract: The title compound, C23H25BrN2O3, crystallizes with two independent mol-ecules in the asymmetric unit (Z' = 2) which differ in the twist of the 5-bromo-1H-indole ring with respect to the plane of the 4-methyl-1,4,5,6,7,8-hexa-hydro-quinoline ring [dihedral angles of 78.55 (9) and 89.70 (8)° in molecules A and B, respectively]. The indole ring is planar in both molecules [maximum deviations = 0.021 (3) and -0.020 (3) Å for the N atom] while the cyclo-hexene ring has adopts a sofa conformation. In the crystal, mol-ecules are linked by pairs of N-H⋯O hydrogen bonds, forming dimers with R1(2)(6) ring motifs. These dimers are connected by N-H⋯O hydrogen bonds, generating chains along [110]. A C-H⋯O contact occurs between the independent mol-ecules.
authors.affiliation: Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 06100 Sihhiye-Ankara, Turkey.
authors.forename: Miyase Gözde
authors.initials: MG
authors.lastname: Gündüz
authors.forename: Ray J
authors.initials: RJ
authors.lastname: Butcher
authors.forename: Sema
authors.initials: S
authors.lastname: Oztürk Yildirim
authors.forename: Ahmed
authors.initials: A
authors.lastname: El-Khouly
authors.forename: Cihat
authors.initials: C
authors.lastname: Safak
authors.forename: Rahime
authors.initials: R
authors.lastname: Simşek