title: Microfluidic chips for immunoassays.
abstract: The use of microfluidic chips for immunoassays has been extensively explored in recent years. The combination of immunoassays and microfluidics affords a promising platform for multiple, sensitive, and automatic point-of-care (POC) diagnostics. In this review, we focus on the description of recent achievements in microfluidic chips for immunoassays categorized by their detection method. Following a brief introduction to the basic principles of each detection method, we examine current microfluidic immunosensor detection systems in detail. We also highlight interesting strategies for sensitive immunosensing configurations, multiplexed analysis, and POC diagnostics in microfluidic immunosensors.
authors.affiliation: Department of Bionanoengineering, Hanyang University, Ansan 426-791, South Korea. ghseong@hanyang.ac.kr
authors.forename: Kwi Nam
authors.initials: KN
authors.lastname: Han
authors.forename: Cheng Ai
authors.initials: CA
authors.lastname: Li
authors.forename: Gi Hun
authors.initials: GH
authors.lastname: Seong
mesh_terms: D015374:Biosensing Techniques / Q000379:methods; D003124:Colorimetry; D055664:Electrochemical Techniques; D005453:Fluorescence; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods*; D049449:Luminescence; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*; D055095:Optics and Photonics; D019095:Point-of-Care Systems; D013016:Sound; D020349:Surface Plasmon Resonance