title: The use of porous titanium granules for treatment of peri-implantitis lesions: preliminary clinical and radiographic results in humans.
abstract: OBJECTIVE
  The aim of the present study is to report on preliminary clinical and radiographic results of using porous titanium granules for treatment of peri-implantitis lesions.
  
  
  METHODS
  A retrospective cohort of 18 implants presenting with peri-implantitis in 16 consecutive patients from two private practices had been evaluated. Treatment included open flap debridement of the lesion, implant surface decontamination using tetracycline, filling of the defect with porous titanium granules and apically positioning of the flaps. Patients' demographics, site and implant characteristics, as well as clinical and radiographic evaluation as baseline and time of follow-up were recorded.
  
  
  RESULTS
  Patients' age ranged from 44 to 79 years with a mean of 61.3 ± 9.5 years. Follow-up time after treating peri-impantitis lesions ranged from 6 to 15 months (mean 7.5 ± 3.9). Two out of the 18 implants still presented with bleeding and suppuration at follow-up and thus the treatment was considered as a failure. This resulted in an overall success rate of 88% for the treatment. Mean bone loss prior to treatment was 4.4 ± 2.1 mm and was reduced following treatment to 2.3 ± 2.1 mm.
  
  
  CONCLUSIONS
  The use of porous titanium granules might be a viable treatment option in cases of peri-implantitis lesions. Further large-scale long-term studies are warranted in order to assess the additional benefit from this treatment option compared to other available alternatives. assiduous.
authors.affiliation: Department of Oral Rehabilitation, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel-Aviv University, Israel.
authors.forename: E
authors.initials: E
authors.lastname: Mijiritsky
authors.forename: G
authors.initials: G
authors.lastname: Yatzkaier
authors.forename: Z
authors.initials: Z
authors.lastname: Mazor
authors.forename: A
authors.initials: A
authors.lastname: Lorean
authors.forename: L
authors.initials: L
authors.lastname: Levin
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D015921:Dental Implants / Q000009:adverse effects*; D019232:Dental Restoration Failure; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D057873:Peri-Implantitis / Q000000981:diagnostic imaging / Q000628:therapy*; D010865:Pilot Projects; D011859:Radiography; D012189:Retrospective Studies; D014025:Titanium / Q000627:therapeutic use*
chemical_list: D015921:Dental Implants; D014025:Titanium