title: Electrospinning tubular scaffolds with tissue-like mechanical properties and biomimetic surface features.
abstract: Electrospinning is a useful technique for generating scaffolds composed of nano- and/or microfibers. Through an innovative modification of the cylindrical target mandrel it is possible to create macrostructural or microstructural invaginations. The former provides complex bulk mechanical behavior reminiscent of native soft tissue; the latter leads to a surface topography reminiscent of intestinal villi.
authors.affiliation: Organovo Inc., San Diego, CA, USA.
authors.forename: Scott
authors.initials: S
authors.lastname: Rapoport
mesh_terms: D001696:Biomechanical Phenomena; D032701:Biomimetics / Q000379:methods*; D004563:Electrochemistry / Q000379:methods; D057139:Nanofibers; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds