title: Re/Mg bimetallic tandem catalysis for [4+2] annulation of benzamides and alkynes via C-H/N-H functionalization.
abstract: A rhenium-magnesium cocatalyzed [4+2] annulation of benzamides and alkynes via C-H/N-H functionalization is described. The reaction features a divergent and high level of diastereoselectivities, which are readily switchable by subtle tuning of reaction conditions. Thus, a wide range of both cis- and trans-3,4-dihydroisoquinolinones is expediently synthesized in a highly atom-economical manner. Moreover, mechanistic studies unraveled a tandem mode of action between rhenium and magnesium in the catalytic cycles.
authors.affiliation: School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China.
authors.forename: Qiuzheng
authors.initials: Q
authors.lastname: Tang
authors.forename: Dexin
authors.initials: D
authors.lastname: Xia
authors.forename: Xiqing
authors.initials: X
authors.lastname: Jin
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhang
authors.forename: Xiao-Qiang
authors.initials: XQ
authors.lastname: Sun
authors.forename: Congyang
authors.initials: C
authors.lastname: Wang