title: Computer-aided detection in computer tomography colonography: a review.
abstract: BACKGROUND
  Colorectal cancer is one of the most common causes of death from cancer. Computer tomography colonography (CTC) - also known as 'virtual colonoscopy' - is a minimally invasive, CT-based procedure that can simulate conventional colonoscopy using three-dimensional computerized reconstructions. In an attempt to improve the method further, a lot of research emphasis has been put on computer-aided detection (CAD) to overcome potential limitations of this examination.
  
  
  OBJECTIVE
  This review recapitulates basic principles of CTC and CAD and highlights the importance of this method as a tool for screening for colorectal cancer.
  
  
  METHODS
  This article reviews the current literature on CAD used with CT colonography.
  
  
  CONCLUSIONS
  CAD potentially helps to improve the detection rate for adenomas, decrease interobserver variability and data set interpretation time.
authors.affiliation: University Hospitals Ulm, Center for Diagnostic and Interventional Radiology, Steinhoevelstr 9, D 89075 Ulm, Germany +49 731 500 61268 ; +49 731 500 61014 ; markus.juchems@uni-ulm.de.
authors.forename: Markus S
authors.initials: MS
authors.lastname: Juchems
authors.forename: Andrea S
authors.initials: AS
authors.lastname: Ernst
authors.forename: Hans-Juergen
authors.initials: HJ
authors.lastname: Brambs
authors.forename: Andrik J
authors.initials: AJ
authors.lastname: Aschoff