title: Complex wavefront shaping for optimal depth-selective focusing in optical coherence tomography.
abstract: We report on an approach to exploit multiple light scattering by shaping the incident wavefront in optical coherence tomography (OCT). Most of the reflected signal from biological tissue consists of multiply scattered light, which is regarded as noise in OCT. A digital mirror device (DMD) is utilized to shape the incident wavefront such that the maximal energy is focused at a specific depth in a highly scattering sample using a coherence-gated reflectance signal as feedback. The proof-of-concept experiment demonstrates that this approach enhances depth-selective focusing in the presence of optical inhomogeneity, and thus extends the penetration depth in spectral domain-OCT (SD-OCT).
authors.affiliation: Dept. of Physics, Korea Advanced Institute of Science. and Technology, Daejeon, 305-701 South Korea.
authors.forename: Jaeduck
authors.initials: J
authors.lastname: Jang
authors.forename: Jaeguyn
authors.initials: J
authors.lastname: Lim
authors.forename: Hyeonseung
authors.initials: H
authors.lastname: Yu
authors.forename: Hyun
authors.initials: H
authors.lastname: Choi
authors.forename: Jinyong
authors.initials: J
authors.lastname: Ha
authors.forename: Jung-Hoon
authors.initials: JH
authors.lastname: Park
authors.forename: Wang-Yuhl
authors.initials: WY
authors.lastname: Oh
authors.forename: Wooyoung
authors.initials: W
authors.lastname: Jang
authors.forename: SeongDeok
authors.initials: S
authors.lastname: Lee
authors.forename: YongKeun
authors.initials: Y
authors.lastname: Park
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D007089:Image Enhancement / Q000295:instrumentation*; D007909:Lenses; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D041623:Tomography, Optical Coherence / Q000295:instrumentation* / Q000379:methods