title: Protein-protein nanoimprinting of silk fibroin films.
abstract: Protein-protein imprinting of silk fibroin is introduced as a rapid, high-throughput method for the fabrication of nanoscale structures in silk films, through the application of heat and pressure. Imprinting on conformal surfaces is demonstrated with minor adjustments to the system, at resolutions comparable to other currently available nonplanar nanoimprint lithography techniques.
authors.affiliation: Tufts University, Department of Biomedical Engineering, Medford, MA 02155, USA.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Brenckle
authors.forename: Hu
authors.initials: H
authors.lastname: Tao
authors.forename: Sunghwan
authors.initials: S
authors.lastname: Kim
authors.forename: Mark
authors.initials: M
authors.lastname: Paquette
authors.forename: David L
authors.initials: DL
authors.lastname: Kaplan
authors.forename: Fiorenzo G
authors.initials: FG
authors.lastname: Omenetto
mesh_terms: D001665:Binding Sites; D003460:Crystallization / Q000379:methods*; D005349:Fibroins / Q000737:chemistry* / Q000648:ultrastructure*; D006358:Hot Temperature; D046911:Macromolecular Substances / Q000737:chemistry; D008422:Materials Testing; D008567:Membranes, Artificial; D008968:Molecular Conformation; D054802:Molecular Imprinting / Q000379:methods*; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure*; D010316:Particle Size; D011312:Pressure; D011485:Protein Binding; D013499:Surface Properties
chemical_list: D046911:Macromolecular Substances; D008567:Membranes, Artificial; C482288:fibroin, silkworm; D005349:Fibroins