title: Biological effects of polycyclic aromatic hydrocarbon derivatives.
abstract: Polycyclic aromatic hydrocarbons (PAHs) are included in various environmental pollutants such as airborne particles and have been reported to induce a variety of toxic effects. On the other hand, PAH derivatives are generated from PAHs both through chemical reaction in the atmosphere and metabolism in the body.PAH derivatives have become known for their specific toxicities such as estrogenic/antiestrogenic activities and oxidative stress, and correlations between the toxicities and structures of PAH derivatives have been shown in recent studies. These studies are indispensable for demonstrating the health effects of PAH derivatives, since they would contribute to the comprehensive toxicity prediction of many kinds of PAH derivatives.
authors.affiliation: Division of Environmental Science and Engineering, Kanazawa University, Ishikawa, Japan. bekkana1105@gmail.com
authors.forename: Kanae
authors.initials: K
authors.lastname: Bekki
authors.forename: Akira
authors.initials: A
authors.lastname: Toriba
authors.forename: Ning
authors.initials: N
authors.lastname: Tang
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kameda
authors.forename: Kazuichi
authors.initials: K
authors.lastname: Hayakawa
mesh_terms: D020847:Estrogen Receptor Modulators / Q000633:toxicity; D004967:Estrogens / Q000633:toxicity; D006801:Humans; D018384:Oxidative Stress / Q000187:drug effects; D011084:Polycyclic Aromatic Hydrocarbons / Q000633:toxicity*; D013329:Structure-Activity Relationship
chemical_list: D020847:Estrogen Receptor Modulators; D004967:Estrogens; D011084:Polycyclic Aromatic Hydrocarbons