title: [Risk factors of mortality in severe chest trauma patients].
abstract: OBJECTIVE
  To investigate the risk factors of mortality in patients with severe chest trauma (SCT).
  
  
  METHODS
  The clinical data of 777 SCT [abbreviated injury scale (AIS) ≥3] patients who were treated in the Chongqing Emergency Medical Center from January 2006 to April 2009 were retrospectively reviewed. Stepwise logistic regression analysis was used to explore 15 possible mortality-related risk factors.
  
  
  RESULTS
  Seven factors were found to be correlated with the mortality of SCT: age, hemorrhagic shock, multiple organ dysfunction syndrome (MODS), pulmonary infection, abdominal organ injury, Glasgow coma scale (GCS) score, and thorax AIS score. Among them five factors were the independent factors that might increase the mortality of SCT: hemorrhagic shock (B=1.710, OR=1.291, P=0.001), MODS (B=3.453, OR=1.028, P<0.001), pulmonary infection (B=2.396, OR=10.941, P<0.001), abdominal organ injury (B=1.542, OR=1.210, P=0.005), and thorax AIS score ≥4 (B=0.487, OR=1.622, P<0.001). Two factors showed protective effects: age ≤60 years (B=-0.035, OR=0.962, P=0.01) and GCS score ≥12 (B=-0.635, OR=0.320, P<0.001).
  
  
  CONCLUSIONS
  Age, disease severity, and complications (hemorrhagic shock, MODS, and pulmonary infection) are independent risk factors of the mortality of SCT. Effective treatment programs targeting these risk factors may improve the outcomes of SCT patients.
authors.affiliation: Department of Cardiothoracic Surgery, China Three Gorges University, Yichang, Hubei, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Liu
authors.forename: Ding-yuan
authors.initials: DY
authors.lastname: Du
authors.forename: Xu
authors.initials: X
authors.lastname: Hu
authors.forename: Dao-kui
authors.initials: DK
authors.lastname: Xia
authors.forename: Xiao-yong
authors.initials: XY
authors.lastname: Xiang
authors.forename: Ji-hong
authors.initials: JH
authors.lastname: Zhou
authors.forename: Chao-bing
authors.initials: CB
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D013898:Thoracic Injuries / Q000401:mortality*; D055815:Young Adult