title: [The role of the small intestine in the development of metabolic syndrome].
abstract: OBJECTIVE
  To comprehensively investigate the function of the small intestine (SI) in metabolic syndrome (MS).
  
  
  METHODS
  Seventy-eight patients with MS were examined using, in addition to clinical studies, comprehensive ones of the function of SI: evaluation of its motor, digestive, and absorptive functions. The specific features of the hormonal and autonomic status were studied in the patients with MS.
  
  
  RESULTS
  Clinical local and common signs of SI lesion were seen in 82.9% of the patients. Examination of SI function revealed its impairments at all stages of hydrolysis and resorption in the presence of hypomotor dyskinesia in the postprandial period and hypersympaticotonia in the patients with MS. New pathogenic patterns were found in relation to the role of hormones in intestinal digestive and absorptive dysfunctions in MS.
  
  
  CONCLUSIONS
  The findings may suggest that SI functional changes found in MS are an important component of its complex pathogenetic circle.
authors.forename: Ia M
authors.initials: IaM
authors.lastname: Vakhrushev
authors.forename: M V
authors.initials: MV
authors.lastname: Liapina
mesh_terms: D001341:Autonomic Nervous System / Q000503:physiopathology; D001786:Blood Glucose; D002784:Cholesterol / Q000097:blood; D004063:Digestion; D004066:Digestive System Diseases / Q000150:complications / Q000378:metabolism / Q000503:physiopathology; D005260:Female; D005769:Gastrointestinal Motility; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000294:innervation / Q000378:metabolism / Q000503:physiopathology; D050356:Lipid Metabolism; D008297:Male; D024821:Metabolic Syndrome / Q000209:etiology / Q000378:metabolism / Q000503:physiopathology; D008875:Middle Aged; D019518:Postprandial Period; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D007328:Insulin; D014280:Triglycerides; D002784:Cholesterol; D006854:Hydrocortisone