title: Genetic testing in couples undergoing assisted reproduction technique protocols.
abstract: BACKGROUND
  An increasing number of couples undergo assisted reproduction techniques (ART) to generate a child, with the risk of the transmission to the offspring of a genetic defect underlying the condition of infertility.
  
  
  OBJECTIVE
  To review the most common genetic causes of infertility and identify the appropriate genetic testing to be carried out to reduce the risk of genetic defect in the offspring.
  
  
  METHODS
  Review of the literature in the field.
  
  
  CONCLUSIONS
  Cytogenetic investigation and screening of the CFTR gene are the only genetics testing suggested in all the couples undergoing ART; other tests should be performed only in selected cases.
authors.affiliation: G. d' Annunzio University, Department of Biomedical Sciences, Via dei Vestini 35 66013, Chieti-Pescara, Italy +39 08713554137 ; +39 08713554135 ; stuppia@unich.it.
authors.forename: Liborio
authors.initials: L
authors.lastname: Stuppia
authors.forename: Valentina
authors.initials: V
authors.lastname: Gatta
authors.forename: Ivana
authors.initials: I
authors.lastname: Antonucci
authors.forename: Rossella
authors.initials: R
authors.lastname: Giuliani
authors.forename: Anna Paola
authors.initials: AP
authors.lastname: Scioletti
authors.forename: Giandomenico
authors.initials: G
authors.lastname: Palka