title: A call for antibiotic alternatives research.
abstract: The persistence and spread of antibiotic resistance, in conjunction with decreased profitability of new antibiotics, have created the dangerous prospect of ineffective therapies against bacterial diseases. National strategies aimed at discovery, development, and definition of the mechanisms of effective antibiotic alternatives, especially for agricultural applications, should be encouraged.
authors.affiliation: Food Safety and Enteric Diseases Unit, National Animal Disease Center, USDA-ARS, Ames, IA 50010, USA. thad.stanton@ars.usda.gov
authors.forename: Thaddeus B
authors.initials: TB
authors.lastname: Stanton
mesh_terms: D000822:Animal Husbandry / Q000379:methods; D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology* / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology / Q000662:veterinary*; D001691:Biological Therapy / Q000379:methods* / Q000639:trends; D055808:Drug Discovery / Q000379:methods* / Q000639:trends; D024881:Drug Resistance, Bacterial; D006291:Health Policy; D006801:Humans; D014730:Veterinary Medicine / Q000379:methods
chemical_list: D000900:Anti-Bacterial Agents