title: Multifocal extra-adrenal paraganglioma evaluated with different PET tracers: comparison between 18F-FDG, 18F-DOPA and 68Ga DOTANOC PET/CT.
abstract: A 40-year-old female patient with suspected multifocal extra-adrenal paraganglioma, on the basis of biochemical, genetic, and conventional imaging data, underwent 18F-FDG, 18F-DOPA and 68Ga DOTANOC PET/CT. FDOPA- and FDG-PET/CT detected a multifocal mediastinal and cervical paraganglioma. 68Ga-DOTANOC PET/CT detected 2 additional lesions compared to the other PET/CT methods. In our case, somatostatin receptor PET/CT with 68Ga-DOTANOC correctly assessed the extent of the disease in a patient with multifocal paraganglioma.
authors.affiliation: From the *Department of Bioimaging and Radiological Sciences, Institute of Nuclear Medicine, Catholic University of the Sacred Heart; and †Department of Thoracic Surgery, Carlo Forlanini Hospital, Rome, Italy.
authors.forename: Giorgio
authors.initials: G
authors.lastname: Treglia
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Cardillo
authors.forename: Antonella
authors.initials: A
authors.lastname: Stefanelli
authors.forename: Davide
authors.initials: D
authors.lastname: Di Franco
authors.forename: Gerard Ngome
authors.initials: GN
authors.lastname: Enang
authors.forename: Alessandro
authors.initials: A
authors.lastname: Giordano
authors.forename: Vittoria
authors.initials: V
authors.lastname: Rufini
mesh_terms: D000328:Adult; D004295:Dihydroxyphenylalanine / Q000031:analogs & derivatives*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D064847:Multimodal Imaging; D009942:Organometallic Compounds; D010236:Paraganglioma, Extra-Adrenal / Q000000981:diagnostic imaging*; D049268:Positron-Emission Tomography; D011849:Radioactive Tracers; D014057:Tomography, X-Ray Computed
chemical_list: C504894:68Ga-DOTANOC; D009942:Organometallic Compounds; D011849:Radioactive Tracers; D019788:Fluorodeoxyglucose F18; C043437:fluorodopa F 18; D004295:Dihydroxyphenylalanine