title: Recurrent prostatic adenocarcinoma with perineural spread to the lumbosacral plexus and sciatic nerve: comparing high resolution MRI with torso and endorectal coils and F-18 FDG and C-11 choline PET/CT.
abstract: We present a patient with unexplained sciatica (radiating pain down the leg) found to have recurrent prostate adenocarcinoma within the sciatic nerve. High resolution MRI, especially use of an endorectal coil, improved visualization of the perineural spread of the disease. We believe that perineural spread resulting in sciatic symptoms in patients with known prostate adenocarcinoma may be an under-recognized phenomenon. The use of non-invasive modalities, high resolution endorectal coil MRI, and C-11 choline PET/CT can assist in the diagnosis of these patients.
authors.affiliation: Department of Neurologic Surgery, Mayo Clinic, Rochester, MN, 55905, USA.
authors.forename: Maya A
authors.initials: MA
authors.lastname: Babu
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Spinner
authors.forename: P James B
authors.initials: PJ
authors.lastname: Dyck
authors.forename: Kimberly K
authors.initials: KK
authors.lastname: Amrami
authors.forename: Mark A
authors.initials: MA
authors.lastname: Nathan
authors.forename: Akira
authors.initials: A
authors.lastname: Kawashima
authors.forename: Benjamin M
authors.initials: BM
authors.lastname: Howe
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D000369:Aged, 80 and over; D001706:Biopsy; D002794:Choline; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008160:Lumbosacral Plexus / Q000000981:diagnostic imaging / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D064847:Multimodal Imaging; D009364:Neoplasm Recurrence, Local; D049268:Positron-Emission Tomography / Q000379:methods*; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D019275:Radiopharmaceuticals; D012584:Sciatic Nerve / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D019043:Vascular Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D017430:Prostate-Specific Antigen; D002794:Choline