title: Blood transfusion therapy for traumatic cardiopulmonary arrest.
abstract: BACKGROUND
  Blood transfusion therapy (BTT), which represents transplantation of living cells, poses several risks. Although BTT is necessary for trauma victims with hemorrhagic shock, it may be futile for patients with blunt traumatic cardiopulmonary arrest (BT-CPA).
  
  
  METHODS
  We retrospectively examined the medical records of consecutive patients with T-CPA. The study period was divided into two periods: The first from 1995-1998, when we used packed red cells (PRC) regardless of the return of spontaneous circulation (ROSC), and the second from 1999-2004, when we did not use PRC before ROSC. The rates of ROSC, admission to the ICU, and survival-to-discharge were compared between these two periods.
  
  
  RESULTS
  We studied the records of 464 patients with BT-CPA (175 in the first period and 289 in the second period). Although the rates of ROSC and admission to the ICU were statistically higher in the first period, there was no statistical difference in the rate of survival-to-discharge between these two periods. In the first period, the rate of ROSC was statistically higher in the non-BTT group than the BTT group. However, for cases in which ROSC was performed and was successful, there were no statistical differences in the rate of admission and survival-to-discharge between the first and second group, and between the BTT and non-BTT group.
  
  
  CONCLUSIONS
  Our retrospective consecutive study shows the possibility that BTT before ROSC for BT-CPA and a treatment strategy that includes this treatment improves the success rate of ROSC, but not the survival rate. BTT is thought to be futile as a treatment for BT-CPA before ROSC.
authors.affiliation: Critical Care and Emergency Center, Yokohama City University Medical Center, 4-57 Urafune-cho, Minami-ku, Yokohama, Japan.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Moriwaki
authors.forename: Mitsugi
authors.initials: M
authors.lastname: Sugiyama
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Tahara
authors.forename: Masayuki
authors.initials: M
authors.lastname: Iwashita
authors.forename: Takayuki
authors.initials: T
authors.lastname: Kosuge
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Toyoda
authors.forename: Shinju
authors.initials: S
authors.lastname: Arata
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Suzuki
keywords: Blood transfusion therapy; return of spontaneous circulation; survival to discharge; traumatic cardiopulmonary arrest