title: [Regularity of changes in main active components of Schisandra chinensis before and after being processed with vinegar].
abstract: OBJECTIVE
  To investigate the regularity of changes in the main active components of Schisandra chinensis preparations before and after being processed with vinegar.
  
  
  METHODS
  High performance liquid chromatography was used to analyze the changes in the content of lignans and organic acids in S. chinensis preparations before and after being processed with vinegar.
  
  
  RESULTS
  After being processed with vinegar, the content of lignans in S. chinensis preparations significantly reduced, while that of organic acids significantly increased. The ratio between them reduced from 1:16 (raw product) to 1:21 (vinegar products).
  
  
  CONCLUSIONS
  The changes in the main pharmacological effects of S. chinensis are related to not only the changes in the contents of lignan and organic acids, but also the significant changes in the ratio relations between the two components. This is of great significance to the correlation among the principle of S. chinensis processed with vinegar and material basis and the changes in pharmacological effects.
authors.affiliation: Institute of Chinese Materia Madica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
authors.forename: Li
authors.initials: L
authors.lastname: Li
authors.forename: Yong-Qing
authors.initials: YQ
authors.lastname: Xiao
authors.forename: Ding-Rong
authors.initials: DR
authors.lastname: Yu
authors.forename: Yin-Lian
authors.initials: YL
authors.lastname: Ma
authors.forename: Ming-Gui
authors.initials: MG
authors.lastname: Zhu
authors.forename: Liang
authors.initials: L
authors.lastname: Chen
mesh_terms: D019342:Acetic Acid; D000143:Acids / Q000032:analysis / Q000302:isolation & purification; D005591:Chemical Fractionation; D002626:Chemistry, Pharmaceutical; D004365:Drugs, Chinese Herbal / Q000032:analysis* / Q000302:isolation & purification; D017705:Lignans / Q000032:analysis / Q000302:isolation & purification; D032141:Schisandra / Q000737:chemistry*
chemical_list: D000143:Acids; D004365:Drugs, Chinese Herbal; D017705:Lignans; D019342:Acetic Acid