title: Dosimetric characterization and use of GAFCHROMIC EBT3 film for IMRT dose verification.
abstract: Radiochromic film has become an important tool to verify dose distributions in highly conformal radiation therapy such as IMRT. Recently, a new generation of these films, EBT3, has become available. EBT3 has the same composition and thickness of the sensitive layer of the previous EBT2 films, but its symmetric layer configuration allows the user to eliminate side orientation dependence, which is reported for EBT2 films. The most important EBT3 characteristics have been investigated, such as response at high-dose levels, sensitivity to scanner orientation and postirradiation coloration, energy and dose rate dependence, and orientation dependence with respect to film side. Additionally, different IMRT fields were measured with both EBT3 and EBT2 films and evaluated using gamma index analysis. The results obtained show that most of the characteristics of EBT3 film are similar to the EBT2 film, but the orientation dependence with respect to film side is completely eliminated in EBT3 films. The study confirms that EBT3 film can be used for clinical practice in the same way as the previous EBT2 film.
authors.affiliation: Azienda Sanitaria Locale TO 4, S.C. Fisica Sanitaria, Ivrea (TO), Italy.
authors.forename: Valeria
authors.initials: V
authors.lastname: Casanova Borca
authors.forename: Massimo
authors.initials: M
authors.lastname: Pasquino
authors.forename: Giuliana
authors.initials: G
authors.lastname: Russo
authors.forename: Pierangelo
authors.initials: P
authors.lastname: Grosso
authors.forename: Domenico
authors.initials: D
authors.lastname: Cante
authors.forename: Piera
authors.initials: P
authors.lastname: Sciacero
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Girelli
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: La Porta
authors.forename: Santi
authors.initials: S
authors.lastname: Tofani
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D005373:Film Dosimetry / Q000295:instrumentation* / Q000379:methods; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity