title: Acute glaucoma in a patient with an Artisan® due to trabecular blockage after combined intravitreal treatment for macular oedema.
abstract: METHODS
  We present a 71-year-old patient with an Artisan(®) implant and macular oedema associated with unsatisfactory response to repeated intravitreal corticosteroids. An intravitreal Trigon(®) and Avastin(®) combined injection was given, and acute glaucoma developed. Anterior chamber washout was performed to resolve the rise in intraocular pressure. In spite of an excellent macular response, this was only temporary, and the corneal endothelium, which had remained competent so far, suffered irreversible damage.
  
  
  CONCLUSIONS
  The combination of both treatments, along with the particular anatomic features in these patients, may have been precipitating factors in this unfortunate outcome.
authors.affiliation: Departamento de Retina, Hospital Clínico San Carlos, Madrid, Spain. dramegara@yahoo.es
authors.forename: A
authors.initials: A
authors.lastname: Valverde-Megías
authors.forename: J
authors.initials: J
authors.lastname: Donate-López
authors.forename: R
authors.initials: R
authors.lastname: Torres-Imaz
authors.forename: D
authors.initials: D
authors.lastname: Díaz Valle
authors.forename: P
authors.initials: P
authors.lastname: Arriola-Villalobos
authors.forename: M
authors.initials: M
authors.lastname: Jiménez-Santos
authors.forename: J
authors.initials: J
authors.lastname: García-Feijoo
mesh_terms: D000208:Acute Disease; D000368:Aged; D020533:Angiogenesis Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage / Q000009:adverse effects*; D000068258:Bevacizumab; D004359:Drug Therapy, Combination; D005901:Glaucoma / Q000139:chemically induced*; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D058449:Intravitreal Injections; D007910:Lenses, Intraocular / Q000009:adverse effects; D008269:Macular Edema / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D020533:Angiogenesis Inhibitors; D061067:Antibodies, Monoclonal, Humanized; D005938:Glucocorticoids; D000068258:Bevacizumab; D014222:Triamcinolone Acetonide