title: Symptoms of depression and smoking behaviors following treatment with transdermal nicotine patch.
abstract: Subscales from the Center for Epidemiologic Studies depression scale (CESD), assessed prior to treatment, were examined as predictors of withdrawal, craving, and affect during the first week of abstinence, as well as smoking abstinence during the first week of abstinence and at the end of treatment. The negative affect and somatic features CESD subscales were related to higher levels of nicotine withdrawal. The relationship between the interpersonal disturbance CESD subscale and nicotine withdrawal approached significance. This study suggests the need to examine novel psychological mechanisms that may account for the relationship between depression symptoms and smoking cessation.
authors.affiliation: Department of Psychiatry and Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. schnoll@mail.med.upenn.edu
authors.forename: Robert A
authors.initials: RA
authors.lastname: Schnoll
authors.forename: Frank T
authors.initials: FT
authors.lastname: Leone
authors.forename: Brian
authors.initials: B
authors.lastname: Hitsman
mesh_terms: D000293:Adolescent; D000328:Adult; D000339:Affect; D059445:Anhedonia; D003863:Depression / Q000175:diagnosis / Q000523:psychology*; D006801:Humans; D016014:Linear Models; D016015:Logistic Models; D008875:Middle Aged; D009538:Nicotine / Q000008:administration & dosage / Q000627:therapeutic use*; D011237:Predictive Value of Tests; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D012907:Smoking / Q000188:drug therapy / Q000523:psychology*; D016540:Smoking Cessation / Q000379:methods / Q000523:psychology*; D013375:Substance Withdrawal Syndrome / Q000523:psychology*; D061485:Tobacco Use Cessation Devices; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D009538:Nicotine