title: Catheter-directed thrombolysis of arterial thrombosis.
abstract: Thrombotic or embolic arterial occlusive disease can lead to profound ischemia and, without emergent revascularization, is associated with significant morbidity and mortality. Significant advances in the management of arterial occlusive disease range from newer thrombolytic agents to innovative catheter designs to enhance thrombolysis and thrombectomy. Most of these advances have been directed toward the management of acute limb ischemia; therefore, we review the management of limb ischemia with emphasis on endovascular interventions.
authors.affiliation: Division of Vascular Imaging and Intervention, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
authors.forename: Stephan
authors.initials: S
authors.lastname: Wicky
authors.forename: Erique Guedes
authors.initials: EG
authors.lastname: Pinto
authors.forename: Rahmi
authors.initials: R
authors.lastname: Oklu
mesh_terms: D057785:Catheters; D006801:Humans; D007511:Ischemia / Q000628:therapy*; D007866:Leg / Q000098:blood supply*; D015912:Thrombolytic Therapy / Q000379:methods*; D013927:Thrombosis / Q000601:surgery / Q000628:therapy*; D016896:Treatment Outcome