title: Ceramic debris in hip prosthesis: correlation between synovial fluid and joint capsule.
abstract: Detection of ceramic particles in synovial fluids allows early diagnosis of ceramic damage, but there is no evidence of a relationship between ceramic debris in the articular space and in the joint capsule. The aim of the present study is to verify if the particles isolated in the synovial fluid are comparable with those stored in the capsular tissue. Twenty-one patients were enrolled. Both synovial fluid and capsular samples were collected during revision surgery and ceramic particles were isolated and analyzed by scanning electron microscopy and energy-dispersive X-ray microanalysis. It resulted a significant correlation between the samples couples (18 out of 21). This study confirms that the synovial fluid analysis can give a clear definition of the presence of particles in the joint capsule.
authors.affiliation: Medical Technology Laboratory, Istituto Ortopedico Rizzoli, Bologna, Italy.
authors.forename: Dalila
authors.initials: D
authors.lastname: De Pasquale
authors.forename: Susanna
authors.initials: S
authors.lastname: Stea
authors.forename: Alina
authors.initials: A
authors.lastname: Beraudi
authors.forename: Monica
authors.initials: M
authors.lastname: Montesi
authors.forename: Stefano
authors.initials: S
authors.lastname: Squarzoni
authors.forename: Aldo
authors.initials: A
authors.lastname: Toni
mesh_terms: D000328:Adult; D000368:Aged; D002516:Ceramics / Q000009:adverse effects / Q000032:analysis*; D004577:Electron Probe Microanalysis; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D017746:Joint Capsule / Q000737:chemistry*; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D011475:Prosthesis Failure; D012086:Reoperation; D013582:Synovial Fluid / Q000737:chemistry*