title: Spectral morphological analysis of skin lesions with a polarization multispectral dermoscope.
abstract: Dermoscopy is the conventional technique used for the clinical inspection of human skin lesions. However, the identification of diagnostically relevant morphologies can become a complex task. We report on the development of a polarization multispectral dermoscope for the in vivo imaging of skin lesions. Linearly polarized illumination at three distinct spectral regions (470, 530 and 625 nm), is performed by high luminance LEDs. Processing of the acquired images, by means of spectral and polarization filtering, produces new contrast images, each one specific for melanin absorption, hemoglobin absorption, and single scattering. Analysis of such images could facilitate the identification of pathological morphologies.
authors.affiliation: European Laboratory for Non-linear Spectroscopy (LENS), Univ. of Florence, 50019 Sesto-Fiorentino, Italy. kapsokalyvas@lens.unifi.it
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Kapsokalyvas
authors.forename: Nicola
authors.initials: N
authors.lastname: Bruscino
authors.forename: Domenico
authors.initials: D
authors.lastname: Alfieri
authors.forename: Vincenzo
authors.initials: V
authors.lastname: de Giorgi
authors.forename: Giovanni
authors.initials: G
authors.lastname: Cannarozzo
authors.forename: Riccardo
authors.initials: R
authors.lastname: Cicchi
authors.forename: Daniela
authors.initials: D
authors.lastname: Massi
authors.forename: Nicola
authors.initials: N
authors.lastname: Pimpinelli
authors.forename: Francesco S
authors.initials: FS
authors.lastname: Pavone
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis*; D046169:Dermoscopy / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D008859:Microscopy, Polarization / Q000295:instrumentation*; D057054:Molecular Imaging / Q000295:instrumentation*; D012878:Skin Neoplasms / Q000378:metabolism* / Q000473:pathology*; D013057:Spectrum Analysis / Q000295:instrumentation*
chemical_list: D014408:Biomarkers, Tumor