title: THE ROLE OF POROUS MEDIA IN MODELING FLUID FLOW WITHIN HOLLOW FIBER MEMBRANES OF THE TOTAL ARTIFICIAL LUNG.
abstract: A numerical study was conducted to analyze fluid flow within hollow fiber membranes of the artificial lungs. The hollow fiber bundle was approximated using a porous media model. In addition, the transport equations were solved using the finite-element formulation based on the Galerkin method of weighted residuals. Comparisons with previously published work on the basis of special cases were performed and found to be in excellent agreement. A Newtonian viscous fluid model for the blood was used. Different flow models for porous media, such as the Brinkman-extended Darcy model, Darcy's law model, and the generalized flow model, were considered. Results were obtained in terms of streamlines, velocity vectors, and pressure distribution for various Reynolds numbers and Darcy numbers. The results from this investigation showed that the pressure drop across the artificial lung device increased with an increase in the Reynolds number. In addition, the pressure drop was found to increase significantly for small Darcy numbers.
authors.affiliation: Biomedical Engineering Department, University of Michigan, Ann Arbor, Michigan 48109, USA ; Section of Vascular Surgery, University of Michigan, Ann Arbor, Michigan 48109, USA.
authors.forename: Khalil
authors.initials: K
authors.lastname: Khanafer
authors.forename: Keith
authors.initials: K
authors.lastname: Cook
authors.forename: Alia
authors.initials: A
authors.lastname: Marafie
keywords: artificial lung; blood oxygenation; hollow fiber membrane