title: [Malaria conjugate vaccine].
abstract: Many malarial antigens are poor immunogens in human. Chemical conjugation is one of the ways to enhance the immunogenicity of those poor immunogens. Its value has been demonstrated in malaria vaccine research. This article introduces the chemical linkers and the carrier proteins, which are often used for protein conjugation, and summarizes the research progress in malarial conjugate vaccine development.
authors.affiliation: Department of Rheumatology and Immunology, Changzheng Hospital, The Second Military Medical University, Shanghai 200003, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Qian
authors.forename: Hu-Ji
authors.initials: HJ
authors.lastname: Xu
mesh_terms: D000953:Antigens, Protozoan / Q000276:immunology; D006801:Humans; D018796:Immunoconjugates; D017780:Malaria Vaccines; D018074:Vaccines, Conjugate
chemical_list: D000953:Antigens, Protozoan; D018796:Immunoconjugates; D017780:Malaria Vaccines; D018074:Vaccines, Conjugate