title: Lack of association between Helicobacter pylori infection and biliary tract diseases.
abstract: There are ambiguous results about the involvement of Helicobacter species in production of hepatobiliary diseases. This study was aimed to investigate any possible association between the presences of Helicobacter spp., their genotypes and occurrence of different biliary diseases. Cultures of 102 bile samples for Helicobacter spp. did not show any growth, but the presence of Helicobacter genus specific DNA (16s rRNA gene) was detected in 3.92% of them. No significant association was found between development of the diseases and presence of the bacteria. All the Helicobacter genus positive samples belonged to H. pylori species and showed vacA+ (s1/m2), cagA- genotypes.
authors.affiliation: Gastroenterology and Liver Diseases Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Somayeh
authors.initials: S
authors.lastname: Jahani Sherafat
authors.forename: Elahe
authors.initials: E
authors.lastname: Tajeddin
authors.forename: Mohammad
authors.initials: M
authors.lastname: Reza Seyyed Majidi
authors.forename: Farzam
authors.initials: F
authors.lastname: Vaziri
authors.forename: Masoud
authors.initials: M
authors.lastname: Alebouyeh
authors.forename: Amir Hooshang
authors.initials: AH
authors.lastname: Mohammad Alizadeh
authors.forename: Ehsan
authors.initials: E
authors.lastname: Nazemalhosseini Mojarad
authors.forename: Mohammad
authors.initials: M
authors.lastname: Reza Zali
mesh_terms: D001646:Bile / Q000382:microbiology*; D002769:Cholelithiasis / Q000209:etiology* / Q000382:microbiology; D005838:Genotype; D016481:Helicobacter Infections / Q000150:complications* / Q000382:microbiology; D016480:Helicobacter pylori / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans