title: DNA-templated Ag nanoclusters as signal transducers for a label-free and resettable keypad lock.
abstract: We present a unique, label-free and resettable molecular keypad lock that utilizes DNA-modulated Ag nanoclusters (Ag NCs) as signal responsers. The present work demonstrates the first example that exonuclease-catalyzed DNA hydrolysis reaction could be used to achieve the RESET function of a molecular keypad without complicated procedures.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, People's Republic of China.
authors.forename: Zhixue
authors.initials: Z
authors.lastname: Zhou
authors.forename: Yaqing
authors.initials: Y
authors.lastname: Liu
authors.forename: Shaojun
authors.initials: S
authors.lastname: Dong
mesh_terms: D055162:Biocatalysis; D004247:DNA / Q000737:chemistry* / Q000378:metabolism*; D005092:Exonucleases / Q000737:chemistry / Q000378:metabolism*; D006868:Hydrolysis; D053768:Metal Nanoparticles / Q000737:chemistry*; D015398:Signal Transduction; D012834:Silver / Q000737:chemistry* / Q000378:metabolism; D013050:Spectrometry, Fluorescence
chemical_list: D012834:Silver; D004247:DNA; D005092:Exonucleases