title: A new "immunological" role for adipocytes in obesity.
abstract: Obesity-induced insulin resistance is associated with low-grade adipose tissue inflammation, but the mechanism driving this process remains unclear. In this issue of Cell Metabolism, a study by Deng et al. (2013) demonstrates a direct immunological role of adipocytes in instigating adipose inflammation via a MHCII-dependent process.
authors.affiliation: Singapore Immunology Network (SIgN), Agency for Science, Technology, and Research (A(∗)STAR), #04-01 Immunos, 8A Biomedical Grove, Singapore 138648, Singapore.
authors.forename: Zuzana
authors.initials: Z
authors.lastname: Hruskova
authors.forename: Subhra K
authors.initials: SK
authors.lastname: Biswas