title: [Ingestion of anabolic steroids and ischaemic stroke. A clinical case report and review of the literature].
abstract: INTRODUCTION. Anabolic-androgenic steroids are synthetic substances derived from testosterone that are employed for their trophic effect on muscle tissue, among other uses. Their consumption can give trigger a series of adverse side effects on the body, including the suppression of the hypothalamus-pituitary-gonadal axis as well as liver, psychiatric and cardiovascular disorders. The most common effects are altered fat profiles and blood pressure values, cardiac remodelling, arrhythmias or myocardial infarcts. CASE REPORT. We report the case of a young male, with a background of anabolic-androgenic steroids abuse, who visited because of an acute neurological focus in the right hemisphere related with an ischaemic stroke. The aetiological study, including cardiac monitoring, echocardiograph and imaging studies (magnetic resonance and arteriography) and lab findings (thrombophilia, serology, autoimmunity, tumour markers) showed no alterations. CONCLUSIONS. The association between consumption of anabolic-androgenic steroids and cardiovascular pathologies is known, but its relation with cerebrovascular disease has not received so much attention from researchers.
authors.affiliation: Servicio de Neurología, Hospital Universitari Germans Trias i Pujol, 08916 Badalona, Espana. carlosgesperon@yahoo.es
authors.forename: Carlos
authors.initials: C
authors.lastname: García-Esperón
authors.forename: José Vicente
authors.initials: JV
authors.lastname: Hervás-García
authors.forename: Marta
authors.initials: M
authors.lastname: Jiménez-González
authors.forename: Natalia
authors.initials: N
authors.lastname: Pérez de la Ossa-Herrero
authors.forename: Meritxell
authors.initials: M
authors.lastname: Gomis-Cortina
authors.forename: Laura
authors.initials: L
authors.lastname: Dorado-Bouix
authors.forename: Elena
authors.initials: E
authors.lastname: López-Cancio Martinez
authors.forename: Carlos H
authors.initials: CH
authors.lastname: Castaño-Duque
authors.forename: Mónica
authors.initials: M
authors.lastname: Millán-Torné
authors.forename: Antonio
authors.initials: A
authors.lastname: Dávalos
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000150:complications; D045930:Anabolic Agents / Q000009:adverse effects*; D002545:Brain Ischemia / Q000139:chemically induced; D002533:Cerebral Angiography; D002976:Clenbuterol / Q000009:adverse effects; D004300:Doping in Sports; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D020244:Infarction, Middle Cerebral Artery / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000628:therapy; D008297:Male; D016139:Martial Arts; D061185:Mechanical Thrombolysis; D009271:Naltrexone / Q000627:therapeutic use; D009277:Nandrolone / Q000009:adverse effects / Q000031:analogs & derivatives; D000077603:Nandrolone Decanoate; D013197:Stanozolol / Q000009:adverse effects; D013256:Steroids / Q000009:adverse effects*; D019966:Substance-Related Disorders / Q000150:complications* / Q000188:drug therapy; D043343:Testosterone Propionate / Q000009:adverse effects; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D045930:Anabolic Agents; D005343:Fibrinolytic Agents; D013256:Steroids; D013197:Stanozolol; D009271:Naltrexone; D009277:Nandrolone; D010959:Tissue Plasminogen Activator; D000077603:Nandrolone Decanoate; D043343:Testosterone Propionate; D002976:Clenbuterol