title: Luminescent biscarbene iridium(III) complexes as living cell imaging reagents.
abstract: Five iridium(III) complexes with two N-heterocyclic carbene (NHC) ligands and an ancillary ligand have been designed and successfully synthesized. With multicolor photoluminescence and low toxicity, these carbene complexes were tested, for the first time, as living cell imaging reagents and showed promise for application beyond the OLED (organic light emitting diode) area.
authors.affiliation: Division of Nanobiomedicine, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, 398 Ruoshui Road, Suzhou Industrial Park, Suzhou, Jiangsu 215123, PR China.
authors.forename: Yuyang
authors.initials: Y
authors.lastname: Zhou
authors.forename: Junli
authors.initials: J
authors.lastname: Jia
authors.forename: Wanfei
authors.initials: W
authors.lastname: Li
authors.forename: Hao
authors.initials: H
authors.lastname: Fei
authors.forename: Ming
authors.initials: M
authors.lastname: Zhou
mesh_terms: D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D003287:Contrast Media / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D006367:HeLa Cells; D006571:Heterocyclic Compounds / Q000737:chemistry; D006801:Humans; D007495:Iridium / Q000737:chemistry*; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D008856:Microscopy, Fluorescence; D013696:Temperature
chemical_list: D003287:Contrast Media; D056831:Coordination Complexes; D006571:Heterocyclic Compounds; C030011:carbene; D007495:Iridium; D008697:Methane