title: Vasopressin for the treatment of neonatal hypotension.
abstract: Vasopressin (pitressin), also known as arginine vasopressin (AVP), is an antidiuretic hormone formed in the hypothalamus and secreted from the posterior pituitary gland. Various forms of exogenous vasopressin exist and have been used in neonates to treat conditions such as diabetes insipidus. Vasopressin has also been studied on a limited basis for use in the treatment of catecholamine-resistant hypotension in vasodilatory shock. Hypotension is a significant problem resulting in increased morbidity in preterm, septic, and postsurgical neonates. This article will discuss the role of vasopressin and its use as a therapeutic agent in the treatment of hypotension in the neonate.
authors.affiliation: All Children’s Hospital, FL 33701, USA. nnpdoctor@gmail.com
authors.forename: Michele J
authors.initials: MJ
authors.lastname: Beaulieu
mesh_terms: D001127:Arginine Vasopressin / Q000009:adverse effects / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007022:Hypotension / Q000188:drug therapy* / Q000451:nursing* / Q000503:physiopathology; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects / Q000503:physiopathology; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000188:drug therapy* / Q000451:nursing*; D007363:Intensive Care Units, Neonatal; D064587:Osmoregulation / Q000187:drug effects / Q000502:physiology; D012307:Risk Factors; D014563:Urodynamics / Q000187:drug effects / Q000502:physiology; D014661:Vasoconstriction / Q000187:drug effects / Q000502:physiology
chemical_list: D001127:Arginine Vasopressin