title: Stability of multispecies bacterial communities: signaling networks may stabilize microbiomes.
abstract: Multispecies bacterial communities can be remarkably stable and resilient even though they consist of cells and species that compete for environmental resources. In silico models suggest that common signals released into the environment may help selected bacterial species cluster at common locations and that sharing of public goods (i.e. molecules produced and released for mutual benefit) can stabilize this coexistence. In contrast, unilateral eavesdropping on signals produced by a potentially invading species may protect a community by keeping invaders away from limited resources. Shared bacterial signals, such as those found in quorum sensing systems, may thus play a key role in fine tuning competition and cooperation within multi-bacterial communities. We suggest that in addition to metabolic complementarity, signaling dynamics may be important in further understanding complex bacterial communities such as the human, animal as well as plant microbiomes.
authors.affiliation: Institute of Biophysics, Biological Research Centre of the Hungarian Academy of Sciences, Szeged, Hungary.
authors.forename: Ádám
authors.initials: Á
authors.lastname: Kerényi
authors.forename: Dóra
authors.initials: D
authors.lastname: Bihary
authors.forename: Vittorio
authors.initials: V
authors.lastname: Venturi
authors.forename: Sándor
authors.initials: S
authors.lastname: Pongor
mesh_terms: D001419:Bacteria / Q000378:metabolism*; D003198:Computer Simulation; D006801:Humans; D054892:Metagenome; D010641:Phenotype; D010935:Plant Diseases / Q000382:microbiology; D053038:Quorum Sensing; D015398:Signal Transduction; D013045:Species Specificity