title: Synthetic biology and the Golem of Prague: philosophical reflections on a suggestive metaphor.
abstract: Not only the public debate about science but even the way scientists conceive their own work is to some extent determined by cultural images. In the case of synthetic biology, literary figures like the Golem of Prague and its successors, such as Frankenstein's monster, seem to suggest themselves. This article reconstructs some cognitive structures underlying the surface of metaphorical thinking and shows how talking about synthetic biology as similar to Golem-making obscures important ontological, pragmatic, and ethical differences.
authors.affiliation: Leo Baeck Institute, 2nd Floor, Arts Two Building, Queen Mary College, University of London, Mile End Road, London E1 4NS, United Kingdom. Charpa@mail.com
authors.forename: Ulrich
authors.initials: U
authors.lastname: Charpa
mesh_terms: D000004:Abbreviations as Topic; D000818:Animals; D035843:Biomedical Research / Q000941:ethics / Q000266:history; D003466:Cultural Characteristics; D003469:Culture; D005201:Fantasy; D005495:Folklore; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007585:Jews / Q000266:history; D007599:Judaism / Q000266:history; D008513:Medicine in Literature; D019365:Metaphor; D012070:Religion and Science; D058615:Synthetic Biology / Q000941:ethics / Q000266:history; D009626:Terminology as Topic