title: Quality of life, fatigue, and activity in Australians with chronic kidney disease: a longitudinal study.
abstract: In this study we investigated the relationship between health-related quality of life, fatigue, and activity levels of people with anemia secondary to chronic kidney disease over a 12 month period following the introduction of an erythropoietin-stimulating agent. Using a longitudinal repeated-measure design, 28 people with chronic kidney disease completed the Short Form-36 Health Survey, Human Activity Profile and Fatigue Severity Scale at the commencement of an erythropoietin-stimulating agent, and then at 3, 6, and 12 months. Over a 12 month period, a significant change was found for health-related quality of life in relation to role-physical, vitality, mental health/emotional well-being, and overall mental health. However, activity levels did not significantly improve during that time. Renal nurses in dialysis units and chronic kidney disease outpatient clinics have repeated and frequent contact with people with chronic kidney disease over long periods of time, and are in an ideal position to routinely assess fatigue and activity levels and to institute timely interventions to optimize health-related quality of life and independent activity.
authors.affiliation: School of Nursing, Queensland University of Technology, Brisbane, Queensland, Australia.
authors.forename: Ann
authors.initials: A
authors.lastname: Bonner
authors.forename: Marie
authors.initials: M
authors.lastname: Caltabiano
authors.forename: Lois
authors.initials: L
authors.lastname: Berlund
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D000740:Anemia / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D015331:Cohort Studies; D004921:Erythropoietin / Q000627:therapeutic use; D005221:Fatigue / Q000175:diagnosis / Q000453:epidemiology* / Q000451:nursing; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000453:epidemiology* / Q000451:nursing / Q000628:therapy; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000451:nursing; D009043:Motor Activity / Q000502:physiology*; D009517:New South Wales; D011788:Quality of Life; D011793:Queensland; D006435:Renal Dialysis / Q000009:adverse effects / Q000379:methods; D018570:Risk Assessment; D012720:Severity of Illness Index; D012737:Sex Factors
chemical_list: D004921:Erythropoietin
keywords: chronic kidney disease; fatigue; nursing; physical activity; quality of life; renal