title: [The effect of physical properties of chitosan on cell activity and on its mechanics property].
abstract: Chitosan is a natural biopolymer and is made up of D-glucosamine subunits linked by beta-(1,4) glycosidic bond. In recent years, the application of chitosan has attracted more and more attention because of its good biological function in cell biology. The properties of chitosan-based biomaterial are attributed to the physical properties and chemical composition of chitosan. The author of this paper summarized recent related studies and progresses of the influence of physical properties of chitosan on cell activity and cell mechanics property at home and abroad. The findings show that most studies mainly focused on the influence of chitosan and cell activity, while few were on cell mechanics property. The related studies of the influence of chitosan on cell will contribute to the explanation for the mechanism of the interaction between chitosan and cell, and provide the theoretical support for the further study.
authors.affiliation: College of Bioengineering, Chongqing University, Chongqing 400044, China.
authors.forename: Shengli
authors.initials: S
authors.lastname: Tian
authors.forename: Zhiyi
authors.initials: Z
authors.lastname: Ye
mesh_terms: D000818:Animals; D002448:Cell Adhesion / Q000187:drug effects; D002454:Cell Differentiation / Q000187:drug effects; D002465:Cell Movement / Q000187:drug effects*; D049109:Cell Proliferation / Q000187:drug effects*; D055598:Chemical Phenomena; D048271:Chitosan / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D023822:Tissue Engineering; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: D048271:Chitosan