title: Thrombolysis for the management of massive pulmonary embolism in pregnancy.
abstract: Massive pulmonary embolism in pregnancy is a major cause of maternal mortality; the management is challenging, and often requires aggressive therapy. Thrombolysis has been used, often with favorable outcome, but has not been previously reported in a patient presenting with an intrauterine death. We present a 29-year-old nulliparous patient who had a massive pulmonary embolus associated with fetal death in the third trimester of pregnancy. Diagnosis of pulmonary embolus was aided by transthoracic echocardiography and the patient was successfully treated with streptokinase.
authors.affiliation: Department of Anesthesia and Surgical Intensive Care, Mansoura University Hospitals, Mansoura, Egypt. m2tawfik@hotmail.com
authors.forename: M M
authors.initials: MM
authors.lastname: Tawfik
authors.forename: M E
authors.initials: ME
authors.lastname: Taman
authors.forename: A A
authors.initials: AA
authors.lastname: Motawea
authors.forename: E
authors.initials: E
authors.lastname: Abdel-Hady
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D004452:Echocardiography; D005260:Female; D005313:Fetal Death; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D000860:Hypoxia / Q000209:etiology / Q000628:therapy; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011263:Pregnancy Trimester, Third; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000188:drug therapy*; D012769:Shock / Q000209:etiology / Q000628:therapy; D013300:Streptokinase / Q000627:therapeutic use; D015912:Thrombolytic Therapy / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006493:Heparin; D013300:Streptokinase