title: Novel SIRT1 mutation linked to autoimmune diabetes in humans.
abstract: Sirtuins are best known for their role in aging but also regulate many different biological processes. A study in this issue of Cell Metabolism (Biason-Lauber et al., 2013) now identifies a mutation in human SIRT1 causing a familial form of autoimmune diabetes.
authors.affiliation: Departments of Immunobiology and Internal Medicine, Yale University School of Medicine, 300 George Street, New Haven, CT 06511, USA.
authors.forename: Jing W
authors.initials: JW
authors.lastname: Hughes
authors.forename: Kevan C
authors.initials: KC
authors.lastname: Herold