title: Multiple atypical recurrent meningiomas 13 years after radiotherapy for unilateral retinoblastoma: case report and review of the literature.
abstract: Radiotherapy is an important treatment modality for intracranial malignancies. Improved survival rates were achieved via a combination of surgery, chemotherapy and radiotherapy. On the other hand, improved survival rates made long-term complications of radiotherapy more apparent. Secondary neoplasms due to cranial irradiation are encountered more commonly in neurosurgical practice. Radiation-induced meningiomas are recognized as a common late complication of radiotherapy. However, radiation-induced meningiomas after radiotherapy for retinoblastoma have been reported rarely. Herein we report a patient who harboured multiple meningiomas 13 years after radiotherapy for unilateral retinoblastoma, which were recurrent despite surgical removal and chemotherapy.
authors.affiliation: Department of Neurosurgery, Istanbul School of Medicine, Istanbul, Turkey.
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Aras
authors.forename: Mehmet O
authors.initials: MO
authors.lastname: Akcakaya
authors.forename: Aydin
authors.initials: A
authors.lastname: Aydoseli
authors.forename: Rasim
authors.initials: R
authors.lastname: Meral
authors.forename: Talat
authors.initials: T
authors.lastname: Kiris
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008579:Meningioma / Q000473:pathology / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D009381:Neoplasms, Radiation-Induced / Q000473:pathology / Q000601:surgery*; D019572:Retinal Neoplasms / Q000532:radiotherapy*; D012175:Retinoblastoma / Q000532:radiotherapy*; D016896:Treatment Outcome