title: Functionalization of biodegradable magnesium alloy implants with alkylphosphonate self-assembled films.
abstract: Mg and Mg-alloys are promising materials for biodegradable implants. In order to slowdown the Mg-alloy (AZ91D) degradation and enhance its biocompatibility, the alloy surface was modified with alkylphosphonate self-assembling films. The binding configuration and the structural organization of alkylphosphonate monolayers on the Mg-alloy surface were investigated using contact angle measurements, FTIR, and XPS. Combination of FTIR and XPS data indicated the presence of several different bonding modes (mono-, di-, and tri dentate) of phosphonate head groups with the alloy surface. The existence of well organized and ordered self-assembled alkylphosphonate monolayers with good barrier protecting properties in a physiological solution is a key step in the development of biocompatible Mg-alloy implants.
authors.affiliation: Department of General and Inorganic Chemistry, Faculty of Chemistry and Technology, University of Split, N. Tesle 10, 21000 Split, Croatia.
authors.forename: Z
authors.initials: Z
authors.lastname: Grubač
authors.forename: M
authors.initials: M
authors.lastname: Metikoš-Huković
authors.forename: R
authors.initials: R
authors.lastname: Babić
authors.forename: I Škugor
authors.initials: IŠ
authors.lastname: Rončević
authors.forename: M
authors.initials: M
authors.lastname: Petravić
authors.forename: R
authors.initials: R
authors.lastname: Peter
mesh_terms: D000497:Alloys / Q000737:chemistry*; D001673:Biodegradation, Environmental; D058266:Dielectric Spectroscopy; D055664:Electrochemical Techniques; D008274:Magnesium / Q000737:chemistry*; D063065:Organophosphonates / Q000737:chemistry*; D010757:Phosphorous Acids / Q000737:chemistry*; D056951:Photoelectron Spectroscopy; D019736:Prostheses and Implants; D012996:Solutions; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D013696:Temperature; D014867:Water / Q000737:chemistry
chemical_list: D000497:Alloys; D063065:Organophosphonates; D010757:Phosphorous Acids; D012996:Solutions; D014867:Water; C570063:phosphonic acid; D008274:Magnesium