title: An epigenetic roadmap for cardiomyocyte differentiation.
abstract: Wamstad et al have provided a robust global analysis of histone markers and gene expression at 4 stages of murine embryonic stem (ES) cell differentiation into cardiac myocytes. This detailed data set will provide a rich opportunity for generating and testing hypotheses related to combinatorial transcriptional regulation of gene expression and epigenetic regulation of cell fate decisions in cardiac lineages.
authors.affiliation: Cardiovascular Institute, Department of Medicine, Institute for Regenerative Medicine and the Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Parmacek
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Epstein