title: Psychopathology in children and adolescents with ASD without mental retardation.
abstract: This study analyzes subclinical psychopathology in children and adolescents with autism spectrum disorders (ASD) without mental retardation with no comorbid disorder, assessed by an extensive general psychopathology interview. The K-SADS-PL was administered to a group of 25 patients with ASD (mean age = 12.80 ± 2.86 years) and 25 healthy controls (mean age 12.52 ± 2.86 years). Significant differences were found between patients with ASD and controls for the domains of: depressive disorder, anxiety separation disorder, agoraphobia and specific phobias, obsessive compulsive disorder (OCD), and attention deficit hyperactivity disorder (ADHD). In patients without a comorbid disorder, we found a profile of subclinical disturbances that suggest high risk for comorbid psychiatric conditions derived from the presence of subthreshold symptomatology.
authors.affiliation: Department of Psychiatry, Hospital General Universitario Gregorio Marañón, Madrid, Spain, marta.caamano@hotmail.com.
authors.forename: Marta
authors.initials: M
authors.lastname: Caamaño
authors.forename: Leticia
authors.initials: L
authors.lastname: Boada
authors.forename: Jessica
authors.initials: J
authors.lastname: Merchán-Naranjo
authors.forename: Carmen
authors.initials: C
authors.lastname: Moreno
authors.forename: Cloe
authors.initials: C
authors.lastname: Llorente
authors.forename: Dolores
authors.initials: D
authors.lastname: Moreno
authors.forename: Celso
authors.initials: C
authors.lastname: Arango
authors.forename: Mara
authors.initials: M
authors.lastname: Parellada
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D002659:Child Development Disorders, Pervasive / Q000150:complications / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications / Q000453:epidemiology / Q000523:psychology*; D008297:Male; D012720:Severity of Illness Index