title: A chemo-enzymatic approach to specifically click-modified RNA.
abstract: The growing interest in single-molecule analysis of RNA calls for programmable enzymatic labeling strategies beyond the horizon of solid-phase synthesized RNAs. Herein we describe an easy and versatile chemo-enzymatic approach to label RNA at its termini or defined internal positions via click-chemistry.
authors.affiliation: Humboldt Universität zu Berlin, Institute for Chemistry, Brook-Taylor-Str. 2, 12489 Berlin, Germany.
authors.forename: Claudine M
authors.initials: CM
authors.lastname: Dojahn
authors.forename: Marlen
authors.initials: M
authors.lastname: Hesse
authors.forename: Christoph
authors.initials: C
authors.lastname: Arenz
mesh_terms: D057930:Click Chemistry; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry* / Q000378:metabolism; D012313:RNA / Q000032:analysis* / Q000138:chemical synthesis / Q000378:metabolism; D013379:Substrate Specificity
chemical_list: D012313:RNA; D012321:DNA-Directed RNA Polymerases