title: Epidural injection of hydroxyethyl starch in the management of postdural puncture headache.
abstract: Epidural blood patch is the standard treatment for postdural puncture headache when symptomatic therapy is ineffective. We report the cases of two patients who received an epidural injection of hydroxyethyl starch when an epidural blood patch was contraindicated; one due to Streptococcus agalactiae bacteraemia and one due to acute leukaemia. Relief of headache was achieved in both patients with no adverse effects. The use of an epidural hydroxyethyl starch injection may be a suitable alternative for treatment of postdural puncture headache if epidural blood patch is contraindicated.
authors.affiliation: Département Anesthésie-Réanimation, Hôpital Mère Enfant, Bron, France.
authors.forename: O
authors.initials: O
authors.lastname: Vassal
authors.forename: M C
authors.initials: MC
authors.lastname: Baud
authors.forename: F
authors.initials: F
authors.lastname: Bolandard
authors.forename: M
authors.initials: M
authors.lastname: Bonnin
authors.forename: E
authors.initials: E
authors.lastname: Vielle
authors.forename: J E
authors.initials: JE
authors.lastname: Bazin
authors.forename: D
authors.initials: D
authors.lastname: Chassard
mesh_terms: D000328:Adult; D015360:Analgesia, Epidural; D016362:Analgesia, Obstetrical; D017217:Blood Patch, Epidural; D000075202:Contraindications; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage / Q000627:therapeutic use*; D007268:Injections, Epidural; D010535:Laparoscopy; D007938:Leukemia / Q000150:complications; D008279:Magnetic Resonance Imaging; D010053:Ovary / Q000601:surgery; D010952:Plasma Substitutes / Q000008:administration & dosage / Q000627:therapeutic use*; D051299:Post-Dural Puncture Headache / Q000628:therapy*; D011247:Pregnancy
chemical_list: D006895:Hydroxyethyl Starch Derivatives; D010952:Plasma Substitutes