title: [Efficacy of Maixuekang capsule on reconvalescents of cerebral infarction and its impact on coagulation function].
abstract: OBJECTIVE
  To observe the clinical efficacy of Maixuekang capsule in reconvalescents of cerebral infarction and its impact on coagulation function.
  
  
  METHODS
  One hundred and twenty cases of reconvalescents of cerebral infarction were randomly divided into treatment and control groups. The 50 cases in the control group were provided with conventional therapy, while the 70 cases in the treatment group were provided with the combination of conventional therapy and Maixuekang capsule for 3 months. Their neurological function and prothrombin time (PT), activated partial thromboplastin time (APTT) clotting enzyme time (TT), fibrinogen (Fib) were measured before and after treatment.
  
  
  RESULTS
  After the treatment, PT, APTT and TT were prolonged compared with those before the treatment in the treatment group (P<0.05), whereas Fib, neurological deficit scores decreased (P<0.01) and significantly different from the control group (P<0.05).
  
  
  CONCLUSIONS
  Maixuekang capsule is among safe and effective drugs in treatment of reconvalescents of cerebral infarction, and can improve the patient's coagulation state.
authors.affiliation: Department of Neurology, The Third hospital of Hangzhou, Hangzhou 310009, China.
authors.forename: Yong-Xing
authors.initials: YX
authors.lastname: Yan
authors.forename: Li-Zhen
authors.initials: LZ
authors.lastname: Liang
authors.forename: Yong-Hui
authors.initials: YH
authors.lastname: Shen
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.forename: Chang-Yang
authors.initials: CY
authors.lastname: Zhong
mesh_terms: D000368:Aged; D001777:Blood Coagulation / Q000187:drug effects; D002214:Capsules / Q000627:therapeutic use; D002544:Cerebral Infarction / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D008297:Male; D011517:Prothrombin Time
chemical_list: D002214:Capsules; D004365:Drugs, Chinese Herbal; D005340:Fibrinogen