title: Capillary electrophoresis determination of  nonsteroidal anti-inflammatory drugs in  wastewater using hollow fiber liquid-phase  microextraction.
abstract: The presence of pharmaceuticals in the environment due to growing worldwide consumption has become an important problem that requires analytical solutions. This paper describes a CE determination for several nonsteroidal anti-inflammatory drugs (ibuprofen, naproxen, ketoprofen, diclofenac, ketorolac, aceclofenac and salicylic acid) in environmental waters using hollow fiber membrane liquid-phase microextraction. The extraction was carried out using a polypropylene membrane supporting dihexyl ether and the electrophoretic separation was performed in acetate buffer (30 mM, pH 4) using ACN as the organic modifier. Detection limits between 0.25 and 0.86 ng/mL were obtained, respectively. The method could be applied to the direct determination of the seven anti-inflammatories in wastewaters, and five of them have been determined or detected in different urban wastewaters.
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, University of Seville, Seville, Spain.
authors.forename: Mercedes
authors.initials: M
authors.lastname: Villar Navarro
authors.forename: María
authors.initials: M
authors.lastname: Ramos Payán
authors.forename: Rut
authors.initials: R
authors.lastname: Fernández-Torres
authors.forename: Miguel A
authors.initials: MA
authors.lastname: Bello-López
authors.forename: Manuel
authors.initials: M
authors.lastname: Callejón Mochón
authors.forename: Alfonso
authors.initials: A
authors.lastname: Guiráum Pérez
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000032:analysis*; D019075:Electrophoresis, Capillary / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D016014:Linear Models; D059627:Liquid Phase Microextraction / Q000295:instrumentation / Q000379:methods*; D062065:Wastewater / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D062065:Wastewater; D014874:Water Pollutants, Chemical