title: Bioactive flavanoids from Glycosmis arborea.
abstract: BACKGROUND
  Glycosmis is a genus of evergreen glabrous shrub and distributed all over India. It possesses various medicinal properties and is used in indigenous medicine for cough, rheumatism, anemia, and jaundice. Glycosmis arborea is a rich source of alkaloids, terpenoids, coumarins, as well as flavonoids.
  
  
  RESULTS
  The chemical investigation of methanol fraction of the leaves of G. arborea led to the isolation of one new flavone C-glycoside along with three known flavanoids, named as 5,7-dihydroxy-2-[4-hydroxy-3-(methoxy methyl) phenyl]-6-C-β-d-glucopyranosyl flavone (4), 5,7,4'-trihydroxy-3'-methoxy flavone (1), 5,4'-dihydroxy-3'-methoxy-7-O-β-d-glucupyranosyl flavanone (2), and 5,4'-dihydroxy-3'-methoxy-7-O-(α-l-rhamnosyl-(1‴→6‴)-β-d-glucopyranosyl) flavanone (3), respectively. The structures of all compounds were elucidated with the help of nuclear magnetic resonance spectrometry. Pure compounds and fractions were evaluated for pest antifeedant and antimicrobial activity.
  
  
  CONCLUSIONS
  Four compounds were isolated from the leaves of G. arborea. Among them, compound 4 showed significant antimicrobial activity.
authors.affiliation: Department of Chemistry, HNB Garhwal University, Srinagar (Garhwal), Uttarakhand 246174, India. devendra_negi@yahoo.com.
authors.forename: Mohammad Faheem
authors.initials: MF
authors.lastname: Khan
authors.forename: Nisha
authors.initials: N
authors.lastname: Negi
authors.forename: Rajnikant
authors.initials: R
authors.lastname: Sharma
authors.forename: Devendra Singh
authors.initials: DS
authors.lastname: Negi