title: Substance use and mental health characteristics associated with cognitive functioning among adults who use methamphetamine.
abstract: This study describes cognitive functioning and its relation to psychiatric and substance use severity among adults with long duration methamphetamine use. Study participants (N = 405) completed a battery of tests from the Automated Neuropsychological Assessment Metrics that examined cognitive accuracy, processing speed, and efficiency. Multivariate analyses indicate that lower accuracy but faster speed on learning, spatial memory and delayed memory were correlated with more days of past-month methamphetamine use. Lifetime months of methamphetamine use was not related to cognitive functioning. Poorer cognitive efficiency was related to other problems, including crack/cocaine use, symptoms of depression, and poorer emotional state.
authors.affiliation: University of California Los Angeles, Integrated Substance Abuse Programs, Los Angeles, California 90025, USA. dherbeck@ucla.edu
authors.forename: Diane M
authors.initials: DM
authors.lastname: Herbeck
authors.forename: Mary-Lynn
authors.initials: ML
authors.lastname: Brecht
mesh_terms: D000328:Adult; D000368:Aged; D001007:Anxiety / Q000453:epidemiology / Q000523:psychology; D000697:Central Nervous System Stimulants / Q000008:administration & dosage / Q000009:adverse effects*; D002908:Chronic Disease; D003072:Cognition Disorders / Q000453:epidemiology / Q000503:physiopathology*; D003866:Depressive Disorder / Q000453:epidemiology / Q000523:psychology; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D007858:Learning / Q000502:physiology; D015141:Los Angeles / Q000453:epidemiology; D008297:Male; D008694:Methamphetamine / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D010342:Patient Acceptance of Health Care / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance / Q000502:physiology; D019966:Substance-Related Disorders / Q000453:epidemiology / Q000503:physiopathology* / Q000523:psychology; D013997:Time Factors; D055815:Young Adult
chemical_list: D000697:Central Nervous System Stimulants; D008694:Methamphetamine