title: Determination of bisphenol A in thermal printing papers treated by alkaline aqueous solution using the combination of single-drop microextraction and HPLC.
abstract: A method for the quantitative determination of bisphenol A in thermal printing paper was developed and validated. Bisphenol A was extracted from the paper samples using 2% NaOH solution, then the extracted analyte was enriched using single-drop microextraction followed by HPLC analysis. Several parameters relating to the single-drop microextraction efficiency including extraction solvent, extraction temperature and time, stirring rate, and pH of donor phase were studied and optimized. Spiked recovery of bisphenol A at 20 and 5 mg/g was found to be 95.8 and 108%, and the method detection limit and method quantification limit was 0.03 and 0.01 mg/g, respectively. Under the optimized conditions, the proposed method was applied to the determination of bisphenol A in seven types of thermal printing paper samples, and the concentration of bisphenol A was found in the range of 0.53-20.9 mg/g. The considerably minimum usage of organic solvents (5 μL 1-octanol) and high enrichment factor (189-197) in the sample preparation are the two highlighted advantages in comparison with previously published works.
authors.affiliation: College of Science, Hebei University of Science and Technology, Shijiazhuang, China.
authors.forename: Leihong
authors.initials: L
authors.lastname: Gao
authors.forename: Jing
authors.initials: J
authors.lastname: Zou
authors.forename: Haihong
authors.initials: H
authors.lastname: Liu
authors.forename: Jingbin
authors.initials: J
authors.lastname: Zeng
authors.forename: Yiru
authors.initials: Y
authors.lastname: Wang
authors.forename: Xi
authors.initials: X
authors.lastname: Chen
mesh_terms: D001559:Benzhydryl Compounds / Q000032:analysis*; D002623:Chemistry Techniques, Analytical / Q000379:methods*; D002851:Chromatography, High Pressure Liquid; D006863:Hydrogen-Ion Concentration; D059627:Liquid Phase Microextraction; D010209:Paper; D010636:Phenols / Q000032:analysis*; D011327:Printing; D014867:Water / Q000737:chemistry; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D010636:Phenols; D014867:Water; C006780:bisphenol A; D000098826:Bisphenol A Compounds