title: Cobas® 4800: a fully automated system for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae.
abstract: Chlamydia trachomatis and Neisseria gonorrhoeae (CT/NG) are the most common sexually transmitted bacterial infections globally and account for the majority of the infections monitored by public health surveillance systems. Therefore, access to diagnostic tools that facilitate identification of these infections is critical to sexually transmitted infection control efforts. The cobas(®) 4800 system is a fully automated system that incorporates nucleic acid extraction and real-time PCR. The cobas 4800 CT/NG assay is one component of the test menu available on this system. The cobas 4800 CT/NG assay has excellent sensitivity and specificity as a result of dual primer targets, it utilizes self-obtained sample types, and is only one assay in a larger menu of tests that are performed on a system that is easy to use and maintain.
authors.affiliation: Indiana University School of Public Health, Department of Epidemiology and Biostatistics, 1025 E Seventh Street, Suite 112, Bloomington, IN 47405, USA. bvanderp@indiana.edu
authors.forename: Barbara
authors.initials: B
authors.lastname: Van Der Pol
mesh_terms: D057205:Automation, Laboratory / Q000295:instrumentation*; D002690:Chlamydia Infections / Q000175:diagnosis*; D002692:Chlamydia trachomatis / Q000235:genetics / Q000302:isolation & purification*; D006069:Gonorrhea / Q000175:diagnosis*; D006801:Humans; D008403:Mass Screening / Q000295:instrumentation; D009344:Neisseria gonorrhoeae / Q000235:genetics / Q000302:isolation & purification*; D009696:Nucleic Acids / Q000302:isolation & purification; D060888:Real-Time Polymerase Chain Reaction / Q000295:instrumentation*
chemical_list: D009696:Nucleic Acids