title: Metastamir-mediated immune evasion: miR-10b downregulates the stress-induced molecule MICB, hence avoid recognition by NKG2D receptor.
abstract: Metastases are responsible for more than 90% of cancer-related deaths. We have recently reported that miR-10b inhibits the expression of MICB, a stress-induced ligand of the activating natural killer (NK)-cell receptor NKG2D. Here, we discuss our findings, which link metastasis formation to immune evasion.
authors.affiliation: Lautenberg Center for General and Tumor Immunology; The Hebrew University; The BioMedical Research Institute; Hadassah Medical School; Jerusalem, Israel.
authors.forename: Pinchas
authors.initials: P
authors.lastname: Tsukerman
authors.forename: Jonatan
authors.initials: J
authors.lastname: Enk
authors.forename: Ofer
authors.initials: O
authors.lastname: Mandelboim