title: The influence of dietary α-solanine on the waxmoth Galleria mellonella L.
abstract: Plant allelochemicals are nonnutritional chemicals that interfere with the biology of herbivores. We posed the hypothesis that ingestion of a glycoalkaloid allelochemical, α-solanine, impairs biological parameters of greater wax moths Galleria mellonella. To test this idea, we reared wax moths on artificial diets with 0.015, 0.15, or 1.5 mg/100 g diet of α-solanine. Addition of α-solanine to the diet affected survival of seventh-instar larvae, pupae, and adults; and female fecundity and fertility. The diet containing the highest α-solanine concentration led to decreased survivorship, fecundity, and fertility. The diets supplemented with α-solanine led to increased malondialdehyde and protein carbonyl contents in midgut and fat body and the effect was dose-dependent. Dietary α-solanine led to increased midgut glutathione S-transferase activity and to decreased fat body glutathione S-transferase activitiy. We infer from these findings that α-solanine influences life history parameters and antioxidative enzyme activities in the midgut and fat body of G. mellonella.
authors.affiliation: Department of Biology, Faculty of Arts and Science, Bülent Ecevit University, Zonguldak, Turkey. endericen@hotmail.com
authors.forename: Ender
authors.initials: E
authors.lastname: Büyükgüzel
authors.forename: Kemal
authors.initials: K
authors.lastname: Büyükgüzel
authors.forename: Meltem
authors.initials: M
authors.lastname: Erdem
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Adamski
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Adamski
authors.forename: Pawel
authors.initials: P
authors.lastname: Marciniak
authors.forename: Kazimierz
authors.initials: K
authors.lastname: Ziemnicki
authors.forename: Emanuela
authors.initials: E
authors.lastname: Ventrella
authors.forename: Laura
authors.initials: L
authors.lastname: Scrano
authors.forename: Sabino Aurelio
authors.initials: SA
authors.lastname: Bufo
mesh_terms: D000818:Animals; D005216:Fat Body / Q000378:metabolism*; D005260:Female; D005298:Fertility / Q000187:drug effects; D041981:Gastrointestinal Tract / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism; D009036:Moths / Q000187:drug effects* / Q000378:metabolism; D018384:Oxidative Stress / Q000187:drug effects*; D050050:Protein Carbonylation / Q000187:drug effects; D012992:Solanine / Q000378:metabolism / Q000494:pharmacology*
chemical_list: C514919:alpha-solanine; D012992:Solanine; D008315:Malondialdehyde; D005982:Glutathione Transferase