title: Effects of carbendazim on Kupffer cell functioning.
abstract: Carbendazim inhibited LPS-induced secretion of TNF-α and NO in the primary culture of rat Kupffer cells. At the same time, phagocytosis evaluated by latex particles engulfment significantly decreased after cell preincubation with carbendazim.
authors.affiliation: Laboratory for Molecular Mechanisms of Infections, Central Research Institute of Epidemiology, Moscow, Russia. viktorov_av@yahoo.com
authors.forename: A V
authors.initials: AV
authors.lastname: Viktorov
authors.forename: V A
authors.initials: VA
authors.lastname: Yurkiv
mesh_terms: D000818:Animals; D001562:Benzimidazoles / Q000737:chemistry / Q000494:pharmacology*; D002219:Carbamates / Q000737:chemistry / Q000494:pharmacology*; D002478:Cells, Cultured; D002851:Chromatography, High Pressure Liquid; D007728:Kupffer Cells / Q000187:drug effects*; D008070:Lipopolysaccharides / Q000494:pharmacology*; D008297:Male; D010587:Phagocytosis / Q000187:drug effects; D051381:Rats; D017207:Rats, Sprague-Dawley; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
chemical_list: D001562:Benzimidazoles; D002219:Carbamates; D008070:Lipopolysaccharides; D014409:Tumor Necrosis Factor-alpha; C006698:carbendazim