title: Primary endobronchial marginal zone B-cell lymphoma of bronchus-associated lymphoid tissue: CT findings in 7 patients.
abstract: OBJECTIVE
  To investigate CT and (18)F-flurodeoxyglucose ((18)F-FDG) positron-emission tomography/CT findings of primary endobronchial marginal zone B-cell lymphoma of the bronchus-associated lymphoid tissue (BALT).
  
  
  METHODS
  From June 2006 through April 2012, seven patients (six female, one male; age range, 21-61 years; mean age, 49 years) were examined who were pathologically diagnosed with the primary endobronchial marginal zone B-cell lymphoma of BALT. We evaluated the locations and characteristics of the lesions on CT and (18)F-FDG-PET/CT scans. The lesions were classified into the following three patterns: 1) solitary intraluminal nodule; 2) several tiny nodular protrusions; and 3) diffuse wall thickening.
  
  
  RESULTS
  A solitary intraluminal nodule was observed in four patients (57.1%), several tiny nodular protrusion in two patients (28.6%), and diffuse wall thickening in one patient (14.3%). The lesions were categorized into 3 major locations: confined to the trachea (n = 3), confined to the lobar bronchus (n = 2), and diffuse involvement of the trachea and both main bronchi (n = 2). All lesions demonstrated homogeneous iso-attenuation as compared with muscle on pre- and post-enhancement scans. Secondary findings in the lungs (n = 3; 42.9%) included postobstructive lobar atelectasis (n = 1), air trapping (n = 1), and pneumonia (n = 1). On (18)F-FDG-PET/CT (n = 5), 4 lesions showed homogeneous uptake with maximum standardized uptake values (mSUV), ranging 2.3-5.7 (mean mSUV: 3.3). One lesion showed little FDG uptake.
  
  
  CONCLUSIONS
  Primary endobronchial marginal zone B-cell lymphoma of the BALT manifests as three distinct patterns on CT, with the solitary intraluminal nodule presenting as the main pattern. Most lesions demonstrate homogeneous but weak FDG uptake on (18)F-FDG-PET/CT.
authors.affiliation: Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Seoul 138-736, Korea.
authors.forename: Ra Gyoung
authors.initials: RG
authors.lastname: Yoon
authors.forename: Mi Young
authors.initials: MY
authors.lastname: Kim
authors.forename: Jae Woo
authors.initials: JW
authors.lastname: Song
authors.forename: Eun Jin
authors.initials: EJ
authors.lastname: Chae
authors.forename: Chang Min
authors.initials: CM
authors.lastname: Choi
authors.forename: SeJin
authors.initials: S
authors.lastname: Jang
mesh_terms: D000328:Adult; D001706:Biopsy; D001980:Bronchi / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007150:Immunohistochemistry; D008221:Lymphoid Tissue / Q000473:pathology; D018442:Lymphoma, B-Cell, Marginal Zone / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: Bronchial neoplasms; Bronchus-associated lymphoid tissue; Lymphoma, non-Hodgkin/diagnosis; Lymphoma, non-Hodgkin/radiotherapy; Positron-emission tomography; Tomography, X-ray computed