title: Targeted CT-guided epidural blood patch for treatment of spontaneous intracranial hypotension due to calcified intradural thoracic disc herniation.
abstract: Calcified thoracic intradural disc herniations have recently been reported as a cause of spontaneous intracranial hypotension (SIH). We report successful treatment of SIH with a targeted CT-guided epidural blood patch. A 57-year-old man presented to the emergency department with a two-week history of progressively debilitating headache. CT and MRI of the brain showed findings consistent with intracranial hypotension and MRI of the spine showed findings consistent with CSF leak. Subsequent CT myelogram of the thoracic spine confirmed the presence of CSF leak and calcified disc herniations at the T6-7, T7-8 and T8-9 levels indenting the ventral dura and spinal cord. The calcified disc herniation at T6-7 had an intradural component and was therefore the most likely site of the CSF leak. Under CT fluoroscopic guidance, a 20-gauge Tuohy needle was progressively advanced into the dorsal epidural space at T6-7. After confirmation of needle tip position, approximately 18cc of the patient's own blood was sterilely removed from an arm vein and slowly re-injected into the dorsal epidural space. With satisfactory achievement of clot formation, the procedure was terminated. The patient tolerated the procedure well. The next morning, his symptoms had completely resolved and he was neurologically intact. At five-week follow up, he was symptom-free. Targeted epidural blood patch at the site of presumed CSF leak can be carried out in a safe and effective manner using CT fluoroscopic guidance and can be an effective alternative to open surgical management in selected patients.
authors.affiliation: Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA. agarwalv@upmc.edu
authors.forename: V
authors.initials: V
authors.lastname: Agarwal
authors.forename: G
authors.initials: G
authors.lastname: Sreedher
authors.forename: W E
authors.initials: WE
authors.lastname: Rothfus
mesh_terms: D017217:Blood Patch, Epidural / Q000379:methods*; D002114:Calcinosis / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D020773:Headache Disorders / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D019585:Intracranial Hypotension / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013355:Subdural Space; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome