title: Cell type specific gene delivery by lentiviral vectors: New options in immunotherapy.
abstract: Many cells of the immune system are defined by distinct surface markers, which can be used to restrict gene delivery exclusively to a cell type of choice. This article explains recent findings about a CD8-specific vector that enhances the killing of tumor cells in TCR-based gene transfer strategies.
authors.affiliation: Molecular Biotechnology and Gene Therapy; Paul-Ehrlich-Institut; Langen, Germany.
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhou
authors.forename: Christian J
authors.initials: CJ
authors.lastname: Buchholz
keywords: CD8+ T lymphocytes; gene transfer; lentiviral vector; targeting; tumor