title: Delayed onset of malignant hyperthermia in the intensive care unit: a rare but life-threatening disorder.
abstract: Malignant hyperthermia (MH) has been described as a rare inherited autosomal dominant metabolic syndrome triggered in patients after exposure to certain inhalation anesthetics and depolarizing muscle relaxants. Typically MH is seen within the operating room and postanesthesia care environment. This case study will discuss a patient with an atypical MH crisis in the intensive care unit. Pathophysiology, genetic basis of and testing for MH-susceptibility as well as the role of the critical care nurse in the management of this potentially fatal disorder will be discussed.
authors.affiliation: Department of Neurosurgery, University of Texas Medical School, Houstan 77030, USA. Nicole.Twine@gmail.com
authors.forename: Nicole
authors.initials: N
authors.lastname: Twine
mesh_terms: D003422:Critical Care; D003620:Dantrolene / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008305:Malignant Hyperthermia / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D024802:Nurse's Role; D013997:Time Factors
chemical_list: D009125:Muscle Relaxants, Central; D003620:Dantrolene