title: Palladium-catalyzed multicomponent synthesis of 2-aryl-2-imidazolines from aryl halides and diamines.
abstract: An efficient palladium-catalyzed three-component reaction that combines aryl halides, isocyanides, and diamines provides access to 2-aryl-2-imidazolines in yields up to 96%. Through variation of the diamine component, the reaction can be extended to the synthesis of 2-aryl-1H-benzimidazoles and 2-aryl-1,4,5,6-tetrahydropyrimidines.
authors.affiliation: Department of Chemistry, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, United Kingdom.
authors.forename: Joanna V
authors.initials: JV
authors.lastname: Geden
authors.forename: Alpa K
authors.initials: AK
authors.lastname: Pancholi
authors.forename: Michael
authors.initials: M
authors.lastname: Shipman
mesh_terms: D002384:Catalysis; D003959:Diamines / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D048288:Imidazolines / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D003959:Diamines; D006846:Hydrocarbons, Halogenated; D048288:Imidazolines; D010165:Palladium