title: (3E,5E)-3,5-Bis(2-chloro-benzyl-idene)-1-propyl-piperidin-4-one.
abstract: The title compound, C22H21Cl2NO, is a derivative of mono-carbonyl analogues of curcumin (MACs). The mol-ecule has an E conformation for each of the olefinic bonds. The 1-propyl-piperidin-4-one ring has a distorted chair conformation with the ring N and the C and O atoms of the carbonyl group deviating from the mean plane of the remaining four ring C atoms by 0.682 (2), -0.134 (3) and -0.340 (4) Å, respectively. The dihedral angle between the benzene rings is 26.5 (1)°. In the crystal, mol-ecules are connected by weak C-H⋯O and C-H⋯π inter-actions.
authors.affiliation: School of Pharmacy, Wenzhou Medical College, Wenzhou, Zhejiang Province 325035, People's Republic of China.
authors.forename: Quanzhi
authors.initials: Q
authors.lastname: Yang
authors.forename: Lingzi
authors.initials: L
authors.lastname: Chen
authors.forename: Bixia
authors.initials: B
authors.lastname: Weng
authors.forename: Lei
authors.initials: L
authors.lastname: Fan
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Wu