title: Metaproteomics: harnessing the power of high performance mass spectrometry to identify the suite of proteins that control metabolic activities in microbial communities.
abstract: The availability of extensive genome information for many different microbes, including unculturable species in mixed communities from environmental samples, has enabled systems-biology interrogation by providing a means to access genomic, transcriptomic, and proteomic information. To this end, metaproteomics exploits the power of high-performance mass spectrometry for extensive characterization of the complete suite of proteins expressed by a microbial community in an environmental sample.
authors.affiliation: Oak Ridge National Laboratory, Oak Ridge, TN 37831-6131, USA. hettichrl@ornl.gov
authors.forename: Robert L
authors.initials: RL
authors.lastname: Hettich
authors.forename: Chongle
authors.initials: C
authors.lastname: Pan
authors.forename: Karuna
authors.initials: K
authors.lastname: Chourey
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Giannone
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism*; D013058:Mass Spectrometry; D020543:Proteome / Q000032:analysis* / Q000378:metabolism*; D040901:Proteomics
chemical_list: D001426:Bacterial Proteins; D020543:Proteome