title: [Clinical applications of arterial spin labeling technique in brain diseases].
abstract: Arterial spin labeling (ASL) technique is a kind of perfusion functional magnetic resonance imaging method that is based on endogenous contrast, and it can measure cerebral blood flow (CBF) noninvasively. The ASL technique has advantages of noninvasiveness, simplicity and relatively lower costs so that it is more suitable for longitudinal studies compared with previous perfusion methods, such as positron emission tomography (PET), single photon emission computed tomography (SPECT), CT and the contrast agent based magnetic resonance perfusion imaging. This paper mainly discusses the current clinical applications of ASL in brain diseases as cerebrovascular diseases, brain tumors, Alzheimer's disease and epilepsy, etc.
authors.affiliation: College of Civil Aviation, Nanjing University of Aeronautics and Astronautics Nanjing 210016, China.
authors.forename: Li
authors.initials: L
authors.lastname: Wang
authors.forename: Gang
authors.initials: G
authors.lastname: Zheng
authors.forename: Tiezhu
authors.initials: T
authors.lastname: Zhao
authors.forename: Chao
authors.initials: C
authors.lastname: Guo
authors.forename: Lin
authors.initials: L
authors.lastname: Li
authors.forename: Guangming
authors.initials: G
authors.lastname: Lu
mesh_terms: D000818:Animals; D001927:Brain Diseases / Q000175:diagnosis*; D001932:Brain Neoplasms / Q000175:diagnosis; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010477:Perfusion; D013113:Spin Labels
chemical_list: D013113:Spin Labels