title: The role of exhaled nitric oxide and exhaled breath condensates in evaluating airway inflammation in asthma.
abstract: BACKGROUND
  Airway inflammation is central to the development and progression of asthma. Monitoring airway inflammation can be invasive and technically difficult, making its use limited in clinical practice. Several advances have been made in non-invasive techniques to monitor and measure inflammation from the airways.
  
  
  OBJECTIVE
  To examine the suitability of exhaled nitric oxide and exhaled breath condensates as diagnostic tools in asthma.
  
  
  METHODS
  The current literature regarding the use of exhaled nitric oxide and exhaled breath condensate to assess and manage asthma was reviewed.
  
  
  CONCLUSIONS
  Exhaled nitric oxide is a clinically useful marker of eosinophilic airway inflammation in asthma. Although showing promise, significant validation and investigation are required before exhaled breath condensate could be utilized in clinical practice.
authors.affiliation: NHRMC Centre for Respiratory and Sleep Medicine, Level 3 Hunter Medical Research Institute, John Hunter Hospital, Locked Bag 1 Hunter Region Mail Centre, Newcastle NSW 2310, Australia +61 02 49214965 ; +61 02 49855850 ; Jodie.simpson@hnehealth.nsw.gov.au.
authors.forename: Jodie L
authors.initials: JL
authors.lastname: Simpson
authors.forename: Peter Ab
authors.initials: PA
authors.lastname: Wark