title: Are somatic symptoms a legitimate part of the depression profile in prostate cancer patients?.
abstract: BACKGROUND
  Although depression is often reported in prostate cancer patients, some tests of depression omit the somatic criteria that are listed for Major Depressive Episode, arguing that these may be confounded by the cancer itself. However, this omission may be challenged in terms of the particular somatic symptoms that have been associated with prostate cancer. Therefore, the present study investigated the relative contribution to total depression scores made by the somatic criteria for Major Depressive Episode that were not caused by prostate cancer.
  
  
  METHODS
  491 prostate cancer patients completed the Zung Self-Rating Depression Scale. Data were analysed to compare the predictive power of 5 subsets of depression on patients' total depressive scores.
  
  
  RESULTS
  Somatic symptoms were the most powerful predictor of total depression scores, followed by anhedonia and depressed mood, with similar findings for depression clinical status. Emotional symptoms and cognitive confusion were not significant predictors of total depression scores but did predict depression clinical status.
  
  
  CONCLUSIONS
  Valid and reliable assessment of depression and selection of appropriate treatment options in prostate cancer patients requires consideration of somatic items which match the DSM-IV-TR criteria for Major Depressive Episode.
authors.affiliation: Brain-Behaviour Research Group, University of New England, New South Wales, Australia. csharpley@onthenet.com.au
authors.forename: Christopher F
authors.initials: CF
authors.lastname: Sharpley
authors.forename: Vicki
authors.initials: V
authors.lastname: Bitsika
authors.forename: David H R
authors.initials: DH
authors.lastname: Christie
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015897:Comorbidity; D003863:Depression / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009517:New South Wales / Q000453:epidemiology; D015995:Prevalence; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology*; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D015203:Reproducibility of Results; D012307:Risk Factors; D012680:Sensitivity and Specificity