title: Concise total synthesis of acortatarin A.
abstract: The spirocyclic pyrrole alkaloid, acortatarin A, which had been isolated from a Chinese medicinal plant, was synthesized from a known olefinic compound by a concise six-step sequence involving N-alkylation of a pyrrole derivative with an α-bromo ketone intermediate as the key step.
authors.affiliation: Laboratory of Applied Bioorganic Chemistry, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.
authors.forename: Takaaki
authors.initials: T
authors.lastname: Teranishi
authors.forename: Masayuki
authors.initials: M
authors.lastname: Kageyama
authors.forename: Shigefumi
authors.initials: S
authors.lastname: Kuwahara
mesh_terms: D000478:Alkylation; D060326:Chemistry Techniques, Synthetic; D004365:Drugs, Chinese Herbal / Q000138:chemical synthesis / Q000737:chemistry; D007700:Kinetics; D009025:Morpholines / Q000138:chemical synthesis* / Q000737:chemistry; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D004365:Drugs, Chinese Herbal; D009025:Morpholines; D013141:Spiro Compounds; C550646:acortatarin A