title: Reactions of organolithiums with dialkyl oxalates. A flow microreactor approach to synthesis of functionalized α-keto esters.
abstract: Reactions of functionalized aryllithiums with dialkyl oxalates were achieved using a flow microreactor to obtain α-keto esters with high selectivity by virtue of fast 1 : 1 micromixing.
authors.affiliation: Department of Synthetic and Biological Chemistry, Graduate School of Engineering, Kyoto University, 615-8510 Kyoto, Japan.
authors.forename: Aiichiro
authors.initials: A
authors.lastname: Nagaki
authors.forename: Daisuke
authors.initials: D
authors.lastname: Ichinari
authors.forename: Jun-ichi
authors.initials: J
authors.lastname: Yoshida
mesh_terms: D001969:Bromobenzenes / Q000737:chemistry; D004952:Esters; D008094:Lithium / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*; D010070:Oxalates / Q000737:chemistry*; D013696:Temperature
chemical_list: D001969:Bromobenzenes; D004952:Esters; D009942:Organometallic Compounds; D010070:Oxalates; D008094:Lithium; C032036:bromobenzene