title: Antineutrophil Cytoplasmic Autoantibody Associated Systemic Vasculitis Is Associated with Epstein - Barr virus in the Setting of HIV Infection.
abstract: EBV has been a leading candidate as a trigger for several autoimmune diseases. We describe an antineutrophil cytoplasmic autoantibody (ANCA) -associated systemic vasculitis as the initial presenting illness of AIDS.
  
  
  
  The patient was diagnosed ANCA -associated systemic vasculitis in the setting of HIV infection because of a high level of ANCA level, crescent glomerulonephritis in pathology, and clinical signs and symptoms compatible with systemic vasculitis. He also had HIV associated lymphadenopathy with scattered. EBV-RNA positive cells and reactive germinal centers.
  
  
  
  EBV genome was found in reactive lymph nodes and, therefore, may be associated with the immunopathogenesis of vasculitis.
authors.affiliation: Department of Internal Medicine, Providence Hospital, Washington DC.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Mirsaeidi
authors.forename: Fatima
authors.initials: F
authors.lastname: Syed
authors.forename: Elaine S
authors.initials: ES
authors.lastname: Jaffe
keywords: ANCA-Associated Vasculitis; EBV; HIV