title: Can maximum surgical blood order schedule be used as a predictor of successful completion of bloodless surgery?
abstract: BACKGROUND
  The Soonchunhyang University Hospital Bloodless Center was established in 2000, and more than 2,000 bloodless surgeries have been performed there since. In this study, the lowest postoperative Hb/preoperative Hb (Hblow/pre) ratio and mortality rates of patients who underwent bloodless surgery were analyzed for each maximum surgical blood order schedule (MSBOS) category to assess whether MSBOS can be used as a predictor of successful completion of bloodless surgery.
  
  
  METHODS
  A total of 971 patients were included. MSBOS was defined as the average number of units of RBCs transfused during each elective surgery. We used the Hblow/pre ratio as an alternative to intraoperative blood loss. Frequency of Hblow/pre ratios ≤0.5, use of transfusion alternatives, and mortality rates were compared across MSBOS categories.
  
  
  RESULTS
  Out of the 971 patients, 701 (72.2%) were categorized as type and screen (T&S), 184 (18.9%) as MSBOS 1, 64 (6.6%) as MSBOS 2, and 22 (2.3%) as MSBOS 4. Transfusion alternatives were used by 397 (40.9%) patients. The frequency of the use of simultaneous erythropoietin and iron, hemostatics, acute normovolemic hemodilution, and Cell Saver (Haemonetics corp., USA) was higher in patients in the higher MSBOS categories. Six (0.6%) patients died within 30 days of surgery. Hblow/pre ratios tended to be lower as the level of MSBOS category increased.
  
  
  CONCLUSIONS
  Surgeries in the higher MSBOS categories tended to be associated with high blood loss and mortality. Active use of transfusion alternatives is recommended in patients in high MSBOS categories who are scheduled to undergo bloodless surgery.
authors.affiliation: Department of Laboratory Medicine, Soonchunhyang University Hospital, Seoul, Korea.
authors.forename: Kyung Il
authors.initials: KI
authors.lastname: Jo
authors.forename: Jeong Won
authors.initials: JW
authors.lastname: Shin
mesh_terms: D016063:Blood Loss, Surgical / Q000401:mortality / Q000517:prevention & control; D057668:Bloodless Medical and Surgical Procedures / Q000379:methods* / Q000401:mortality; D004921:Erythropoietin / Q000627:therapeutic use; D006438:Hemodilution; D006454:Hemoglobins / Q000032:analysis; D006490:Hemostatics / Q000627:therapeutic use; D006785:Hospitals, University; D006801:Humans; D007501:Iron / Q000627:therapeutic use; D017063:Outcome Assessment, Health Care; D062606:Tertiary Care Centers
chemical_list: D006454:Hemoglobins; D006490:Hemostatics; D004921:Erythropoietin; D007501:Iron
keywords: Bloodless surgery; Hblow/pre ratio; MSBOS; Mortality