title: The influence of Goishi tea on adipocytokines in obese mice.
abstract: This study investigated the influence of Goishi-tea on visceral fat weight in induced obese mice. Mice were divided into two main groups, normal and obesity. In obesity group, mice were fed with high-fat diet. Goishi-tea including its fractions (ethyl-acetate layer and water layer) was administrated in normal and obesity three sub-groups. Results showed no influence of Goishi-tea in normal group. However, visceral fat weight, size of adipose cell and cholesterol level were significantly decreased in obesity group fed Goishi-tea compared to control group. Moreover, adiponectin levels tended to increase and adipocytokines has significant values lower in obesity group fed Goishi-tea compared to control group. Interestingly, Goishi tea involved in the high-fat diet induced-obese mice can inhibit fat accumulation and maintain adiponectins without increasing tumor necrosis factor-alpha and interleukin-6. It would be beneficial for the prevention of metabolic syndrome and obesity-related disorder.
authors.affiliation: Department of Pharmacy, Kochi Medical School Hospital, 185-1 Kohasu, Kochi 783-8505, Japan. jm-yokotaj@kochi-u.ac.jp
authors.forename: Junko
authors.initials: J
authors.lastname: Yokota
authors.forename: Kohei
authors.initials: K
authors.lastname: Jobu
authors.forename: Saburo
authors.initials: S
authors.lastname: Yoshioka
authors.forename: Takehiro
authors.initials: T
authors.lastname: Kashiwagi
authors.forename: Tomoko
authors.initials: T
authors.lastname: Shimamura
authors.forename: Hironori
authors.initials: H
authors.lastname: Moriyama
authors.forename: Shuzo
authors.initials: S
authors.lastname: Murata
authors.forename: Masao
authors.initials: M
authors.lastname: Ohishi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Ukeda
authors.forename: Mitsuhiko
authors.initials: M
authors.lastname: Miyamura
mesh_terms: D054392:Adipokines / Q000378:metabolism*; D000273:Adipose Tissue / Q000187:drug effects* / Q000378:metabolism* / Q000503:physiopathology; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D028241:Camellia sinensis / Q000737:chemistry*; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat / Q000378:metabolism; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008813:Mice, Inbred ICR; D008820:Mice, Obese; D009765:Obesity / Q000378:metabolism; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage*; D013662:Tea / Q000737:chemistry
chemical_list: D054392:Adipokines; D010936:Plant Extracts; D013662:Tea