title: [Personalized treatment of colorectal cancer in old age].
abstract: The incidence of colorectal cancer in elderly patients is rising. Due to changing demographics the topic of personalized treatment of colorectal cancer in old age is of growing importance for interdisciplinary tumor therapy. Besides the oncological results for this group of patients, aspects of risk consideration for treatment, quality of life and the personal conception of life become more relevant. This report covers the changes in comorbidities associated with old age and illustrates the impact on therapeutic strategies and results. Furthermore, it exemplifies potential individual adaption of standardized therapy regimens in multimorbid patients and provides information on possible strategies to improve treatment outcome.
authors.affiliation: Chirurgische Klinik und Hochschulambulanz I, Klinik für Allgemein-, Viszeral- und Gefäßchirurgie, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Freie- und Humboldt-Universität zu Berlin, Hindenburgdamm 30, 12200, Berlin, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Gröne
authors.forename: M E
authors.initials: ME
authors.lastname: Kreis
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology; D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000523:psychology / Q000601:surgery*; D003131:Combined Modality Therapy; D015897:Comorbidity; D018572:Disease-Free Survival; D005260:Female; D005858:Germany; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D010347:Patient Care Planning; D018579:Patient Selection; D011157:Population Dynamics; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality / Q000523:psychology; D011788:Quality of Life / Q000523:psychology; D012307:Risk Factors