title: Oxime cross-linked injectable hydrogels for catheter delivery.
abstract: Catheter delivery of therapeutic materials is important for developing minimally invasive treatment approaches. However, the majority of injectable materials gel rapidly upon mixing and/or heating to body temperature. The application of an oxime cross-linked hydrogel system is demonstrated. The system has a broad range of tunable gelation rates, is capable of injection through a catheter, and exhibits rapid gelation upon injection into tissue.
authors.affiliation: Department of Bioengineering, University of California, San Diego, 92093, USA.
authors.forename: Gregory N
authors.initials: GN
authors.lastname: Grover
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Braden
authors.forename: Karen L
authors.initials: KL
authors.lastname: Christman
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D057785:Catheters; D020100:Hydrogels / Q000737:chemistry*; D007267:Injections; D010091:Oximes / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D020100:Hydrogels; D010091:Oximes; D011092:Polyethylene Glycols
keywords: catheters; injectable hydrogels; oxime cross-linking