title: Method of diagnosing pre-eclampsia.
abstract: Pre-eclampsia is a pregnancy-specific disorder that causes a high degree of maternal and fetal morbidity and mortality. Despite many recent advances in the field, the diagnosis, treatment and prevention of pre-eclampsia remain elusive. The current patent application provides evidence for a marker of pre-eclampsia, a 26.6-kDa polypeptide, which is present in pre-eclamptic women and absent in normal controls. The prospect of developing a laboratory test for the diagnosis of pre-eclampsia is exciting, as is the possibility for risk-stratification and potential therapies.
authors.affiliation: Mayo Clinic, Division of Nephrology and Hypertension, 200 First Street SW, Rochester, Minnesota 55905, USA +1 507 284 3594 ; +1 507 284 1161 ; garovic.vesna@mayo.edu.
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Wagner
authors.forename: Vesna D
authors.initials: VD
authors.lastname: Garovic