title: [High intake of lycopene together with low intake of red meat increases the total antioxidant status].
abstract: The body's antioxidant systems are able to remove free radicals, thus protecting the body from the damage they may cause. They can be estimated, as a whole, through the determination of total antioxidant status (TAS). This biomarker can be modulated by dietary factors through the incorporation of substances with antioxidant or prooxidant properties. The aim of this study was to estimate the intake of antioxidant nutrients and specific food groups, and its correlation with TAS. Forty-five male volunteers between 50 and 75 years were randomly selected from a medical consultation. The study included a TAS determination by ABTS and a nutritional interview where corporal composition was studied through anthropometry and the habitual consumption of nutrients was estimated by means of 24 hour diary and food consumption frequency questionnaire. Statistical analysis was performed by using Pearson or Spearman correlation coefficient (p < 0.05). TAS was positively correlated with lycopene consumption (r = 0.295; p = 0.049), and negatively with red meat intake (r = -0.403; p = 0.007), while intake of other studied antioxidant nutrients did not correlate significantly with TAS. In conclusion, high intake of lycopene and reduced red meat consumption increase TAS.
authors.affiliation: Laboratorio de Enfermedades Metabólicas y Cáncer, Facultad de Farmacia y Bioquímica, Universidad Juan Agustín Maza.
authors.forename: Diego
authors.initials: D
authors.lastname: Messina
authors.forename: Rafael
authors.initials: R
authors.lastname: Pérez Elizalde
authors.forename: Catalina
authors.initials: C
authors.lastname: Soto
authors.forename: Ana
authors.initials: A
authors.lastname: Uvilla
authors.forename: José Daniel
authors.initials: JD
authors.lastname: López Laur
authors.forename: Constanza
authors.initials: C
authors.lastname: López Fontana
mesh_terms: D000368:Aged; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000032:analysis* / Q000378:metabolism; D001118:Argentina; D015415:Biomarkers / Q000032:analysis / Q000378:metabolism; D001823:Body Composition; D002338:Carotenoids / Q000008:administration & dosage* / Q000378:metabolism; D003430:Cross-Sectional Studies; D015930:Diet Records; D005247:Feeding Behavior; D006801:Humans; D000077276:Lycopene; D008297:Male; D008460:Meat; D008875:Middle Aged; D011795:Surveys and Questionnaires
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D002338:Carotenoids; D000077276:Lycopene