title: Anterior segment variations after posterior chamber phakic intraocular lens implantation in myopic eyes.
abstract: OBJECTIVE
  To evaluate anterior segment variations after posterior chamber phakic intraocular lens (pIOL) implantation in myopic eyes.
  
  
  METHODS
  Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
  
  
  METHODS
  Cohort study.
  
  
  METHODS
  Patients with high myopia were scheduled for nontoric Implantable Collamer Lens pIOL or toric Implantable Collamer Lens pIOL implantation. Anterior segment optical coherence tomography was performed to evaluate the anterior segment variations over time and the impact of physiologic accommodation and change in brightness after pIOL implantation. Slitlamp photography of the anterior segment was taken after pupil dilation to calculate pIOL rotation.
  
  
  RESULTS
  There was significantly improved visual acuity and refractive status after implantation of both pIOLs. Anterior segment axial variations had good stability 6 months postoperatively. However, nontoric pIOL rotation occurred in 1 eye 7 months postoperatively and rotation of the toric pIOL occurred in 2 eyes at 3 months and 6 months. Stimulations of -4.0 diopters (D) and -8.0 D led to significant changes in anterior chamber depth (ACD) based on the lens (ACD-lens), ACD after pIOL implantation, distance between the pIOL posterior surface and the lens anterior surface (pIOL-lens), and pupil diameter. Increasing ambient light brightness could reduce the ACD-lens and pIOL-lens.
  
  
  CONCLUSIONS
  Both pIOLs had good axial stability in myopic eyes 6 months postoperatively; however, rotational stability over time could not be determined. The physiologic adjustment and change in brightness could influence the anterior segment significantly in eyes with a pIOL.
authors.affiliation: State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
authors.forename: Haotian
authors.initials: H
authors.lastname: Lin
authors.forename: Pisong
authors.initials: P
authors.lastname: Yan
authors.forename: Keming
authors.initials: K
authors.lastname: Yu
authors.forename: Lixia
authors.initials: L
authors.lastname: Luo
authors.forename: Jingjing
authors.initials: J
authors.lastname: Chen
authors.forename: Zhuoling
authors.initials: Z
authors.lastname: Lin
authors.forename: Weirong
authors.initials: W
authors.lastname: Chen
mesh_terms: D000065:Accommodation, Ocular / Q000502:physiology*; D000293:Adolescent; D000328:Adult; D000869:Anterior Eye Segment / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000503:physiopathology / Q000601:surgery*; D054120:Phakic Intraocular Lenses; D011184:Postoperative Period; D011446:Prospective Studies; D011680:Pupil / Q000502:physiology*; D012029:Refraction, Ocular / Q000502:physiology; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult