title: Osteoporosis: genetic determinants and relationship with cardiovascular disease.
abstract: Osteoporosis has become one of the major public health problems, affecting about two hundred million people worldwide, including one third of all postmenopausal women. The paper presents a review of the current literature concerning the pathophysiology and the most common genetic and environmental determinants that account for the individual predisposition to age-related osteoporosis. Particular emphasis is placed on the specific linkage between the causative factors of osteoporosis and atherosclerotic cardiovascular disease.
authors.affiliation: Department of Pathophysiology, Wroclaw Medical University, Wroclaw, Poland. malsobie@poczta.onet.pl
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Sobieszczańska
authors.forename: Jakub
authors.initials: J
authors.lastname: Jonkisz
authors.forename: Mateusz
authors.initials: M
authors.lastname: Tabin
authors.forename: Krystyna
authors.initials: K
authors.lastname: Laszki-Szcząchor
mesh_terms: D002318:Cardiovascular Diseases / Q000150:complications*; D020022:Genetic Predisposition to Disease; D006801:Humans; D010024:Osteoporosis / Q000150:complications* / Q000235:genetics*