title: Validity of a new respiratory resistance measurement device to detect glottal area change.
abstract: OBJECTIVE
  To determine the correlation between respiratory resistance (Rr) values measured with the Airflow Perturbation Device (APD) to laryngoscopic images of glottal area (GA) in feigned paradoxical vocal fold motion (PVFM), also known as vocal cord dysfunction.
  
  
  OBJECTIVE
  There is a strong inverse relationship between Rr and GA such that laryngeal constriction can be detected and quantified by APD-measured Rr.
  
  
  METHODS
  Prospective, single subject study.
  
  
  METHODS
  A healthy adult feigned breathing that was characteristic of PVFM. Rr and GA were simultaneously recorded, synchronized, and analyzed for three complete breathing cycles with significant glottal constriction occurring during inspiration.
  
  
  RESULTS
  Cross-correlation analysis revealed a strong negative correlation (-0.824) between GA and Rr during feigned PVFM breathing such that Rr increased when GA decreased.
  
  
  CONCLUSIONS
  APD-measured Rr appears to be a viable noninvasive method for diagnostic screening and monitoring of treatment outcomes for individuals presenting with dyspnea related to PVFM.
authors.affiliation: Department of Speech-Language Pathology, Loyola University Maryland, Baltimore, Maryland, USA. sgallena@loyola.edu
authors.forename: Sally J K
authors.initials: SJ
authors.lastname: Gallena
authors.forename: Wei
authors.initials: W
authors.lastname: Tian
authors.forename: Arthur T
authors.initials: AT
authors.lastname: Johnson
authors.forename: Jafar
authors.initials: J
authors.lastname: Vossoughi
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Sarles
authors.forename: Nancy Pearl
authors.initials: NP
authors.lastname: Solomon
mesh_terms: D000403:Airway Resistance; D001696:Biomechanical Phenomena; D003251:Constriction, Pathologic; D004417:Dyspnea / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D004867:Equipment Design; D005260:Female; D005931:Glottis / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D007828:Laryngoscopy; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D015203:Reproducibility of Results; D012119:Respiration; D012129:Respiratory Function Tests / Q000295:instrumentation*; D049489:Stroboscopy; D014741:Video Recording; D064706:Vocal Cord Dysfunction / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology