title: Computed tomography angiography gravitational gradient as an imaging sign of slow flow.
abstract: Intraluminal layering of iodinated contrast on a single axial computed tomography image is described as a possible sign of slow arterial flow and is quantified using a new region of interest-based metric, that is, gravitational gradient. The metric was measured in 4 patients who demonstrated this phenomenon and in the aorta of 10 patients with no clinical sign suggestive of slow flow. Future studies are needed to validate the relationship between gravitational gradient, slow flow, and patient outcome.
authors.affiliation: Thoraco-Abdominal Imaging, University of Virginia Health System, Charlottesville, VA, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Hanley
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Mitsouras
authors.forename: Michael L
authors.initials: ML
authors.lastname: Steigner
authors.forename: Shadpour
authors.initials: S
authors.lastname: Demehri
authors.forename: Jason
authors.initials: J
authors.lastname: Signorelli
authors.forename: Kanako K
authors.initials: KK
authors.lastname: Kumamaru
authors.forename: Frank J
authors.initials: FJ
authors.lastname: Rybicki
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000000981:diagnostic imaging*; D017545:Aortic Aneurysm, Thoracic / Q000000981:diagnostic imaging*; D001027:Aortography / Q000379:methods*; D001783:Blood Flow Velocity; D003287:Contrast Media / Q000008:administration & dosage*; D006112:Gravitation; D006801:Humans; D007479:Iopamidol / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D007479:Iopamidol