title: Aquagenic pruritus induced by clomipramine.
abstract: OBJECTIVE
  Aquagenic pruritus is the development of severe, prickling-like skin discomfort without observable skin lesions that is evoked by contact with water at any temperature.
  
  
  METHODS
  This is a case report of a man presenting with aquagenic pruritus after starting clomipramine treatment for anxiety and depression.
  
  
  RESULTS
  The patient's aquagenic pruritus resolved after discontinuing the clomipramine but reemerged when treatment was restarted.
  
  
  CONCLUSIONS
  A greater awareness and knowledge about aquagenic pruritus among physicians could help improve the clinical recognition and management of this clinical entity.
authors.affiliation: Department of Psychiatry and Mental Health, Universidade Federal Fluminense (MSM-UFF). Rua Marquês do Paraná, 303 - 3º andar do Prédio Anexo. Niterói, RJ. Brazil; Institute of Psychiatry, Universidade Federal do Rio de Janeiro (IPUB - UFRJ). Avenida Venceslau Brás, 71 fundos. Rio de Janeiro, RJ. Brasil. Electronic address: mmendlowicz@yahoo.com.
authors.forename: Mauro Vitor
authors.initials: MV
authors.lastname: Mendlowicz
authors.forename: João Luiz Lopes
authors.initials: JL
authors.lastname: Lima
authors.forename: Leonardo Franklin
authors.initials: LF
authors.lastname: Fontenelle
mesh_terms: D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects* / Q000627:therapeutic use; D002997:Clomipramine / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D016584:Panic Disorder / Q000188:drug therapy; D011537:Pruritus / Q000139:chemically induced*; D012867:Skin / Q000187:drug effects; D014867:Water / Q000009:adverse effects
chemical_list: D000929:Antidepressive Agents, Tricyclic; D014867:Water; D002997:Clomipramine
keywords: Adverse effects; Antidepressive agents; Clomipramine; Pruritus; Skin diseases