title: Synthesis of functionalized allenamides from ynamides by enolate Claisen rearrangement.
abstract: The Claisen rearrangement of N-Boc glycinates derived from ynamido-alcohols affords an efficient and stereoselective access to highly functionalized allenamides. These compounds undergo silver-catalyzed cyclization to 3-pyrrolines which are useful precursors for the synthesis of substituted pyrrolidines.
authors.affiliation: Laboratoire de Chimie Organique, ESPCI Paris Tech, CNRS, 10 rue Vauquelin, 75231 Paris Cedex 05, France.
authors.forename: Julien
authors.initials: J
authors.lastname: Brioche
authors.forename: Christophe
authors.initials: C
authors.lastname: Meyer
authors.forename: Janine
authors.initials: J
authors.lastname: Cossy