title: Angiographic findings in 2 children with cerebral paragonimiasis with hemorrhage.
abstract: Hemorrhagic events associated with cerebral paragonimiasis are not rare, especially in children and adolescents; however, angiographic evidence of cerebrovascular involvement has not been reported. The authors describe angiographic abnormalities of the cerebral arteries seen in 2 children in whom cerebral paragonimiasis was associated with hemorrhagic stroke. The patients presented with acute intracerebral and subarachnoid hemorrhage. Angiography revealed a beaded appearance and long segmental narrowing of arteries, consistent with arteritis. In both patients, involved vessels were seen in the area of the hemorrhage. The vascular changes and the hemorrhage, together with new lesions that developed close to the hemorrhage and improved after praziquantel treatment, were attributed to paragonimiasis. Further study of the frequency and mechanism of hemorrhagic cerebrovascular complications associated with cerebral paragonimiasis is needed.
authors.affiliation: Department of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing, China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Chen
authors.forename: Jingyu
authors.initials: J
authors.lastname: Chen
authors.forename: Hongpin
authors.initials: H
authors.lastname: Miao
authors.forename: Fei
authors.initials: F
authors.lastname: Li
authors.forename: Hua
authors.initials: H
authors.lastname: Feng
authors.forename: Gang
authors.initials: G
authors.lastname: Zhu
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D001921:Brain / Q000469:parasitology* / Q000473:pathology; D020809:Central Nervous System Helminthiasis / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging*; D002533:Cerebral Angiography; D002536:Cerebral Arteries / Q000000981:diagnostic imaging* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D020300:Intracranial Hemorrhages / Q000000981:diagnostic imaging* / Q000469:parasitology*; D008279:Magnetic Resonance Imaging; D008297:Male; D010237:Paragonimiasis / Q000000981:diagnostic imaging*; D010238:Paragonimus / Q000276:immunology / Q000302:isolation & purification*; D011223:Praziquantel / Q000627:therapeutic use; D019233:Retreatment; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging / Q000469:parasitology; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000871:Anthelmintics; D007074:Immunoglobulin G; D011223:Praziquantel