title: [Staphylococcus saprophyticus isolated from urine culture in outpatients: epidemiology and antimicrobial susceptibility (Label Bio Elbeuf study - November 2007-July 2009)].
abstract: OBJECTIVE
  The aim of the study was to determine the distribution and the antibiotic susceptibility of Staphylococcus saprophyticus patterns isolated from urine culture in outpatients (population: 57,000, Elbeuf, Normandie, France).
  
  
  METHODS
  Prospective study from November 2007 to October 2009 in collaboration with three private medical laboratories. Determination of susceptibility to oxacillin by disk diffusion (cefoxitin, and moxalactam), automated method (Vitek BioMérieux 2) and mecA PCR's detection. Determination of the minimum inhibitory concentration by microbroth dilution for other antibiotics.
  
  
  RESULTS
  Five thousand and fifty-one bacterial strains isolated, 91 strains of S. saprophyticus (1.8%), 89 in women (2.25%) and two in men (0.18%). S. saprophyticus represented 10.3% and 14.5% of isolates (women respectively aged between 11 and 30; 16 and 20 years); S. saprophyticus is isolated less frequently in winter. mecA PCR detection was positive for two strains. All strains tested were susceptible to ciprofloxacin and furans. Only one strain is resistant to cotrimoxazole.
  
  
  CONCLUSIONS
  S. saprophyticus is found mostly in women between 11 to 30 years. Cotrimoxazole (after susceptibility testing) is efficient in case of S. saprophyticus's cystitis. Furans (probabilistic treatment) have to be reevaluated because of the potential for serious adverse effects.
authors.affiliation: Label Bio, 36, rue du Neubourg, 76500 Elbeuf, France. roland.fabre0781@orange.fr
authors.forename: R
authors.initials: R
authors.lastname: Fabre
authors.forename: A
authors.initials: A
authors.lastname: Mérens
authors.forename: C
authors.initials: C
authors.lastname: Tabone-Ledan
authors.forename: G
authors.initials: G
authors.lastname: Epifanoff
authors.forename: J-D
authors.initials: JD
authors.lastname: Cavallo
authors.forename: I
authors.initials: I
authors.lastname: Ternois
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002648:Child; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010045:Outpatients / Q000706:statistics & numerical data; D010068:Oxacillin / Q000494:pharmacology; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology / Q000652:urine*; D057790:Staphylococcus saprophyticus / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification*; D055815:Young Adult
chemical_list: D000890:Anti-Infective Agents; D010068:Oxacillin