title: Parasitic myomas after laparoscopic-assisted myomectomy in multiple endocrine neoplasia type 1.
abstract: Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant hereditary disorder that develops multiple tumors arising from various endocrine organs, including the parathyroid gland, endocrine pancreas and pituitary gland. Although mesenchymal tumors can be an integral part of the syndrome, parasitic peritoneal myomas have never been described in an MEN1 patient. Seven years after laparoscopic-assisted myomectomy, parasitic peritoneal myomas were diagnosed in a 31-year-old woman with situs inversus totalis and previous history of parathyroid adenoma. Subsequently, MEN1 was clinically diagnosed by identification of endocrine pancreatic, adrenal and pituitary tumors. Genetic analysis revealed a heterozygous germline mutation in the splice donor sequence of intron 6 of the MEN1 gene. Although rare, parasitic peritoneal myomas could potentially be associated with MEN1 syndrome.
authors.affiliation: Department of Obstetrics and Gynecology, Gifu Prefectural Tajimi Hospital, Tajimi, Japan.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Takeda
authors.forename: Akihiro
authors.initials: A
authors.lastname: Sakurai
authors.forename: Sanae
authors.initials: S
authors.lastname: Imoto
authors.forename: Hiromi
authors.initials: H
authors.lastname: Nakamura
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000209:etiology / Q000503:physiopathology* / Q000601:surgery; D018761:Multiple Endocrine Neoplasia Type 1 / Q000150:complications / Q000503:physiopathology*; D009214:Myoma / Q000209:etiology* / Q000601:surgery; D010534:Peritoneal Neoplasms / Q000209:etiology* / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology* / Q000601:surgery; D012857:Situs Inversus / Q000150:complications; D016896:Treatment Outcome; D063186:Uterine Myomectomy; D055815:Young Adult