title: Lacrimal gland sparing IgG4-related disease in the orbit.
abstract: OBJECTIVE
  We report an unusual case of orbital IgG4-related disease and discuss the distinguishing characteristics of the ophthalmic disease subtype.
  
  
  METHODS
  Case report.
  
  
  METHODS
  Literature review and case description.
  
  
  RESULTS
  Although lacrimal gland involvement has always been reported and elevated serum IgG4 is commonly observed, our case demonstrated neither in light of biopsy-proven IgG4 orbital involvement. A course of systemic steroids resolved our patient's periorbital abnormalities.
  
  
  CONCLUSIONS
  IgG4-related orbital disease mandates a high index of suspicion, and should be confirmed by tissue biopsy. Possible progression to MALT lymphoma necessitates close surveillance and may require repeat biopsy.
authors.forename: Tanya T
authors.initials: TT
authors.lastname: Khan
authors.forename: Shams K
authors.initials: SK
authors.lastname: Halat
authors.forename: Adham B
authors.initials: AB
authors.lastname: Al Hariri
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology / Q000378:metabolism*; D007765:Lacrimal Apparatus / Q000378:metabolism* / Q000473:pathology; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis* / Q000276:immunology / Q000378:metabolism; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000276:immunology / Q000378:metabolism*; D014057:Tomography, X-Ray Computed; D055815:Young Adult
chemical_list: D007074:Immunoglobulin G