title: Evidence of person-to-person transmission within a family cluster of novel coronavirus infections, United Kingdom, February 2013.
abstract: In February 2013, novel coronavirus (nCoV) infection was diagnosed in an adult male in the United Kingdom with severe respiratory illness, who had travelled to Pakistan and Saudi Arabia 10 days before symptom onset. Contact tracing identified two secondary cases among family members without recent travel: one developed severe respiratory illness and died, the other an influenza-like illness. No other severe cases were identified or nCoV detected in respiratory samples among 135 contacts followed for 10 days.
mesh_terms: D016000:Cluster Analysis; D016358:Contact Tracing / Q000706:statistics & numerical data; D017934:Coronavirus / Q000302:isolation & purification*; D018352:Coronavirus Infections / Q000453:epidemiology / Q000628:therapy / Q000635:transmission*; D003428:Cross Infection / Q000453:epidemiology / Q000628:therapy / Q000635:transmission*; D004196:Disease Outbreaks; D005260:Female; D006282:Health Personnel / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D011481:Protective Clothing; D015980:Public Health Practice / Q000592:standards*; D012111:Residence Characteristics; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000628:therapy / Q000635:transmission*; D014195:Travel; D006113:United Kingdom / Q000453:epidemiology