title: Effects of acute exercise on postprandial triglyceride response after a high-fat meal in overweight black and white adolescents.
abstract: OBJECTIVE
  We examined the effects of acute exercise on postprandial triglyceride (TG) metabolism following a high-fat meal in overweight black vs white adolescents.
  
  
  METHODS
  Twenty-one black and 17 white adolescents (12-18 yrs, body mass index 85th percentile) were evaluated twice, during control versus exercise trials, 1-4 weeks apart, in a counterbalanced randomized design. In the control trial, participants performed no exercise on day 1. In the exercise trial, participants performed a single bout of 60-min exercise (50% VO2 peak) on a cycle ergometer on day 1. On day 2 of both trials, participants consumed a high-fat breakfast (70% calories from fat) and blood was sampled for TG concentration in the fasted state and for 6 h postprandially.
  
  
  RESULTS
  There was a significant main effect of condition on postprandial peak TG concentration (P=0.01) and TG area under the curve (AUC) (P=0.003), suggesting that independent of race, peak TG and TG-AUC was lower in the exercise trial vs control trial. Including Tanner stage, gender, total fat (kg) and visceral adipose tissue (VAT) as independent variables, stepwise multiple regression analyses revealed that in whites, VAT was the strongest (P<0.05) predictor of postprandial TG-AUC, explaining 56 and 25% of the variances in TG-AUC in the control and exercise trials, respectively. In blacks, VAT was not associated with postprandial TG-AUC, independent of trial.
  
  
  CONCLUSIONS
  A single bout of aerobic exercise preceding a high-fat meal is beneficial to reduce postprandial TG concentrations in overweight white adolescents to a greater extent than black adolescents, particularly those with increased visceral adiposity.
authors.affiliation: Division of Weight Management and Wellness, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA 15224, USA. SoJung.Lee@chp.edu
authors.forename: S
authors.initials: S
authors.lastname: Lee
authors.forename: S F
authors.initials: SF
authors.lastname: Burns
authors.forename: D
authors.initials: D
authors.lastname: White
authors.forename: J L
authors.initials: JL
authors.lastname: Kuk
authors.forename: S
authors.initials: S
authors.lastname: Arslanian
mesh_terms: D000293:Adolescent; D001741:Black or African American / Q000706:statistics & numerical data*; D000704:Analysis of Variance; D019540:Area Under Curve; D001642:Bicycling; D001786:Blood Glucose / Q000378:metabolism; D001823:Body Composition; D015992:Body Mass Index; D002096:C-Peptide / Q000097:blood; D002648:Child; D059305:Diet, High-Fat; D015444:Exercise; D005215:Fasting; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood* / Q000208:ethnology; D007328:Insulin / Q000097:blood; D050152:Intra-Abdominal Fat / Q000378:metabolism; D008297:Male; D050177:Overweight / Q000097:blood* / Q000208:ethnology*; D019518:Postprandial Period; D014280:Triglycerides / Q000097:blood*; D014481:United States; D044465:White People / Q000706:statistics & numerical data*
chemical_list: D001786:Blood Glucose; D002096:C-Peptide; D007328:Insulin; D014280:Triglycerides