title: A Rare Cause of Diffuse Parenchymal Lung Disease together with Granulomatous Reaction: Pulmonary Amyloidosis.
abstract: Amyloidosis is a heterogeneous group of disorder associated with the deposition of protein in an abnormal fibrillar form. Primary Sjögren's syndrome (PSS) is a systemic inflammatory disorder that commonly affects the exocrine glands. The reported frequency of pulmonary involvement in PSS varies widely, ranging from 9% to 75%. Pulmonary involvement occurs in light-chain (AL) amyloidosis and is uncommon in the reactive (AA) and hereditary forms. Herein we present a case of PSS associated diffuse multinodular amyloidosis in the lung. We followed up the patient without treatment for three years. There are only minimal lung symptoms related to lung infiltration. In conclusion, pulmonary involvement in SS is an extremely rare clinical manifestation and usually has a good survival rate without treatment.
authors.affiliation: Department of Chest Diseases, Faculty of Medicine, Erciyes University, 38039 Kayseri, Turkey.
authors.forename: Zuhal
authors.initials: Z
authors.lastname: Ozer Simsek
authors.forename: Fatma Sema
authors.initials: FS
authors.lastname: Oymak
authors.forename: Nuri
authors.initials: N
authors.lastname: Tutar
authors.forename: Ozlem
authors.initials: O
authors.lastname: Canoz
authors.forename: Ramazan
authors.initials: R
authors.lastname: Demir