title: Retinal involvement of Paracoccioidomycosis: A Case Report.
abstract: OBJECTIVE
  to describe the clinicopathologic features and treatment of a rare case of systemic paracoccidioidomycosis with choroidal and retinal involvement.
  
  
  METHODS
  retrospective interventional case report.
  
  
  METHODS
  A 36-year-old young man with visual impairment in left eye with anterior uveitis and presence of whitish perimacular choroidal nodule, multiple underlying whitish spots and mid-periphery exudative retinal detachment. A primary extensive work-up for systemic infectious, autoimmune, neoplasic or inflammatory conditions was performed and high-resolution computer tomography scan demonstrated asymmetric parietal thickening of the trachea and bilateral diffuse multiple lobular opacities. Pulmonary bronchoscopy/biopsy of larynx, trachea and bronchial tube were also performed. Histopathological evaluation showed characteristic of Paracoccidioidomycosis.
  
  
  METHODS
  Patient was treated with oral sulphadiazine (1.5 g/day).
  
  
  METHODS
  Anterior uveitis, retinal examination, histopathological evaluation and primary clinical outcome were observed during systemic treatment.
  
  
  RESULTS
  After 3 months of irregular treatment, choroidal lesions decreased in size forming atrophic scars and fibrotic spots; however visual acuity did not show any improvement.
  
  
  CONCLUSIONS
  We report a rare case of systemic paracoccidioidomycosis with choroidal and retinal involvement treated with oral sulphadiazine.
authors.affiliation: Department of Ophthalmology, University of São Paulo, School of Medicine (Hospital das Clínicas da Universidade de São Paulo- São Paulo- HC-USP)- Brazil ; Department of Ophthalmology, Santa Casa de São Paulo, Brazil.
authors.forename: Thais Z
authors.initials: TZ
authors.lastname: Igami
authors.forename: Francisco
authors.initials: F
authors.lastname: Solano
authors.forename: Rony C
authors.initials: RC
authors.lastname: Preti
authors.forename: Carla
authors.initials: C
authors.lastname: Pagliari
authors.forename: Walter Y
authors.initials: WY
authors.lastname: Takahashi
authors.forename: Richard Y
authors.initials: RY
authors.lastname: Hida
keywords: Paracoccioidomycosis; eye; retina