title: [Association between age and chorioretinal hemodynamics in normal volunteers examined with laser speckle flowgraphy].
abstract: OBJECTIVE
  To investigate the relationship between age and chorioretinal hemodynamics in normal volunteers examined with Laser speckle flowgraphy (LSFG-NAVI).
  
  
  METHODS
  107 eyes of 107 healthy volunteers aged from 21 to 78 years old were included. Laser speckle flowgraphy measurements of relative blood velocity (mean blur rate: MBR), skewness in the wave of blood velocity (Skew) and blowout score (BOS), which indicates ease of blood flow, were obtained as parameters of chorioretinal hemodynamics. MBR and BOS were measured on the optic disc and macula, and BOS and Skew were measured in retinal arteries and veins.
  
  
  RESULTS
  There was a negative correlation between age and MBR on the optic disc and macula. There was a negative correlation between age and BOS on the optic disc, macula, retinal arteries and retinal veins.
  
  
  CONCLUSIONS
  There was a negative correlation between MBR, BOS and age in all measurement areas. MBR and BOS may serve as indexes for a new interpretation of fundus pathology including age-related arterial sclerosis.
authors.affiliation: Department of Opthalmology, Tokyo Women's Medical University, 8-1 Kawada-cho, Shinjuku-ku, Tokyo 162-8666, Japan. a-tamura@oph.twmu.ac.jp
authors.forename: Akiko
authors.initials: A
authors.lastname: Tamura
authors.forename: Akiko
authors.initials: A
authors.lastname: Kogure
authors.forename: Goro
authors.initials: G
authors.lastname: Watanabe
authors.forename: Shoji
authors.initials: S
authors.lastname: Kishi
authors.forename: Sadao
authors.initials: S
authors.lastname: Hori
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001783:Blood Flow Velocity / Q000502:physiology; D005123:Eye / Q000098:blood supply*; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D017078:Laser-Doppler Flowmetry / Q000379:methods; D008833:Microcirculation / Q000502:physiology; D008875:Middle Aged; D055815:Young Adult