title: Role of c-MYC in tumor-associated macrophages and cancer progression.
abstract: Transcription factors of the MYC family regulate several homeostatic cell functions, and their role as proto-oncogenes has been the focus of interest for decades. We have recently demonstrated that c-MYC is expressed by tumor-associated macrophages (TAMs) and regulates their phenotype and pro-tumor activities in vivo.
authors.affiliation: Laboratory of Molecular and Genetic Cardiovascular Pathophysiology; Department of Epidemiology, Atherothrombosis and Imaging; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC); Madrid, Spain.
authors.forename: Oscar M
authors.initials: OM
authors.lastname: Pello
authors.forename: Vicente
authors.initials: V
authors.lastname: Andrés
keywords: angiogenesis; c-MYC; cancer; macrophage differentiation/maturation; tumor-associated macrophage