title: LC analysis and pharmacokinetic study of synthetic piperlonguminine in rat plasma after oral administration.
abstract: Only one kind of synthesized alkaloid, piperlonguminine, was used to understand the interference of the other alkaloids in pharmacokinetic study using HPLC/UV in rat plasma after oral administration. Compared with the previous report, it was clarified that mixed alkaloids such as piperine and the other extract from Piper longum Linn did not interfere with the results.
authors.affiliation: Institute of Mongolian Medicine Chemistry, Inner Mongolia University, 235 Da Xue West Road, Hohhot, 010020, People's Republic of China.
authors.forename: Erdenebaatar
authors.initials: E
authors.lastname: Sarnaizul
authors.forename: Gereltu
authors.initials: G
authors.lastname: Borjihan
authors.forename: Huricha
authors.initials: H
authors.lastname: Baigude
authors.lastname: Aona
authors.lastname: Menghe
authors.lastname: Narisu
authors.lastname: Zhaorigetu
mesh_terms: D000284:Administration, Oral; D000470:Alkaloids / Q000737:chemistry; D000818:Animals; D052117:Benzodioxoles / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004148:Dioxolanes / Q000008:administration & dosage / Q000097:blood* / Q000737:chemistry / Q000493:pharmacokinetics*; D016014:Linear Models; D008297:Male; D010880:Piperidines / Q000737:chemistry; D053284:Polyunsaturated Alkamides / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013056:Spectrophotometry, Ultraviolet; D010881:Piperidones
chemical_list: D000470:Alkaloids; D052117:Benzodioxoles; D004148:Dioxolanes; D010880:Piperidines; D053284:Polyunsaturated Alkamides; C498077:piperlongumine; D010881:Piperidones; C008922:piperine