title: Performance of two commercial assays for detecting hepatitis E virus RNA in acute or chronic infections.
abstract: We assessed the performance of the Ceeram and Altona assays, the first two commercially available hepatitis E virus (HEV) RNA assays, using serial dilutions of 4 HEV-positive reference samples (genotypes 3a, 3c, 3e, and 3f). Both assays provided good analytical sensitivity and high reproducibility for detecting genotype 3 HEV RNA.
authors.affiliation: INSERM, U1043, Centre de Physiopathologie de Toulouse Purpan, Toulouse, France. abravanel.f@chu-toulouse.fr
authors.forename: Florence
authors.initials: F
authors.lastname: Abravanel
authors.forename: Sabine
authors.initials: S
authors.lastname: Chapuy-Regaud
authors.forename: Sébastien
authors.initials: S
authors.lastname: Lhomme
authors.forename: Martine
authors.initials: M
authors.lastname: Dubois
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Peron
authors.forename: Laurent
authors.initials: L
authors.lastname: Alric
authors.forename: Lionel
authors.initials: L
authors.lastname: Rostaing
authors.forename: Nassim
authors.initials: N
authors.lastname: Kamar
authors.forename: Jacques
authors.initials: J
authors.lastname: Izopet
mesh_terms: D016751:Hepatitis E / Q000175:diagnosis*; D016752:Hepatitis E virus / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D012367:RNA, Viral