title: Therapeutic potential of umbilical cord mesenchymal stromal cells transplantation for cerebral palsy: a case report.
abstract: Cerebral palsy is the most common motor disability in childhood. In current paper, we first report our clinical data regarding administration of umbilical cord mesenchymal stem cells (MSCs) transplantation in treatment of cerebral palsy. A 5-year-old girl with cerebral palsy was treated with multiple times of intravenous and intrathecal administration of MSCs derived from her young sister and was followed up for 28 months. The gross motor dysfunction was improved. Other benefits included enhanced immunity, increased physical strength, and adjusted speech and comprehension. Temporary low-grade fever was the only side effect during the treatment. MSCs may be a safe and effective therapy to improve symptoms in children with cerebral palsy.
authors.affiliation: Cell Therapy Center, 323 Hospital of People's Liberation Army, Xi'an 710054, China.
authors.forename: Liming
authors.initials: L
authors.lastname: Wang
authors.forename: Haijie
authors.initials: H
authors.lastname: Ji
authors.forename: Jianjun
authors.initials: J
authors.lastname: Zhou
authors.forename: Jiang
authors.initials: J
authors.lastname: Xie
authors.forename: Zhanqiang
authors.initials: Z
authors.lastname: Zhong
authors.forename: Ming
authors.initials: M
authors.lastname: Li
authors.forename: Wen
authors.initials: W
authors.lastname: Bai
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.forename: Zijia
authors.initials: Z
authors.lastname: Zhang
authors.forename: Xuejun
authors.initials: X
authors.lastname: Wang
authors.forename: Delin
authors.initials: D
authors.lastname: Zhu
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Liu
authors.forename: Mingyuan
authors.initials: M
authors.lastname: Wu