title: Autogenous bone versus deproteinised bovine bone matrix in 1-stage lateral sinus floor elevation in the severely atrophied maxilla: a randomised controlled trial.
abstract: OBJECTIVE
  To compare 100% deproteinised bovine bone matrix (DBBM) grafts (test group) with 100% autogenous bone (AB) grafts (control group) for lateral maxillary sinus floor elevation in a parallel group, superiority, randomised controlled trial.
  
  
  METHODS
  Patients with 1 to 3 mm of residual bone height below the maxillary sinus were randomised for sinus floor elevation with DBBM and AB grafts and simultaneous implant placement. Randomisation was computer generated with allocation concealment by sealed envelopes and the radiographic examiner was blinded to group assignment. The abutment connection was performed 8 months after surgery and insertion of the provisional prostheses was performed 9 months after surgery. Outcome variables were implant failures, prosthetic failures, complications, chair time, postoperative pain and radiographic bone level 6 months after loading.
  
  
  RESULTS
  Forty patients were randomised: 20 (32 implants) to the DBBM group and 20 (27 implants) to the AB group. One patient from the AB group dropped out. Two implant failures occurred in the DBBM group and no implant failure occurred in the AB group (P = 0.4872). All of the planned prostheses could be delivered. One complication occurred in the DBBM group and 2 in the AB group (P = 0.6050). Chair time was shorter for the DBBM group, with a difference of 27.3 minutes (P = 0.0428). Pain difference measured with a visual analogue scale for 6 days post-surgery was 0.2 in favour of the DBBM group (P = 0.6838). The difference in vertical bone height was 0.0 mm (95% CI -1.1, 1.1; P = 0.9703) and the difference in marginal bone level was 0.3 in favour of AB (95% CI -0.3, 0.9; P = 0.3220).
  
  
  CONCLUSIONS
  No differences apart from chair time were observed when comparing DBBM and AB grafts with simultaneous implant placement in sinus elevation.
authors.affiliation: Politecnico delle Marche, Ancona, Italy. mauromerli@gmail.com
authors.forename: Mauro
authors.initials: M
authors.lastname: Merli
authors.forename: Marco
authors.initials: M
authors.lastname: Moscatelli
authors.forename: Giorgia
authors.initials: G
authors.lastname: Mariotti
authors.forename: Roberto
authors.initials: R
authors.lastname: Rotundo
authors.forename: Michele
authors.initials: M
authors.lastname: Nieri
mesh_terms: D000328:Adult; D000368:Aged; D016301:Alveolar Bone Loss / Q000601:surgery*; D000539:Alveolar Process / Q000000981:diagnostic imaging; D018786:Bone Substitutes; D016025:Bone Transplantation; D003094:Collagen; D003758:Dental Implantation, Endosseous / Q000379:methods; D019094:Dental Prosthesis, Implant-Supported; D019232:Dental Restoration Failure; D005260:Female; D006801:Humans; D008297:Male; D008437:Maxilla / Q000601:surgery*; D008567:Membranes, Artificial; D008875:Middle Aged; D008903:Minerals; D011859:Radiography; D016037:Single-Blind Method; D059546:Sinus Floor Augmentation / Q000379:methods*; D016896:Treatment Outcome
chemical_list: C106416:Bio-Gide; C077540:Bio-Oss; D018786:Bone Substitutes; D008567:Membranes, Artificial; D008903:Minerals; D003094:Collagen