title: Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype.
abstract: In this study, we investigated the associations between single-nucleotide polymorphisms in GAB2 (rs2373115), GSK3B (rs6438552) and SORL1 (rs641120) and Alzheimer's disease (AD), both alone and in combination with the APOE*4 allele.
authors.affiliation: Laboratory of Neuroscience, Department and Institute of Psychiatry, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Giselle
authors.initials: G
authors.lastname: Izzo
authors.forename: Orestes V
authors.initials: OV
authors.lastname: Forlenza
authors.forename: Bernardo dos
authors.initials: Bd
authors.lastname: Santos
authors.forename: Paulo H F
authors.initials: PH
authors.lastname: Bertolucci
authors.forename: Elida B
authors.initials: EB
authors.lastname: Ojopi
authors.forename: Wagner F
authors.initials: WF
authors.lastname: Gattaz
authors.forename: Daniel Shikanai
authors.initials: DS
authors.lastname: Kerr
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000235:genetics*; D017668:Age of Onset; D000368:Aged; D000544:Alzheimer Disease / Q000235:genetics*; D053327:Apolipoprotein E4 / Q000235:genetics*; D003598:Cytoskeletal Proteins / Q000235:genetics*; D005260:Female; D006801:Humans; D026502:LDL-Receptor Related Proteins / Q000235:genetics*; D008297:Male; D026901:Membrane Transport Proteins / Q000235:genetics*; D009687:Nuclear Proteins / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D012307:Risk Factors
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D053327:Apolipoprotein E4; D003598:Cytoskeletal Proteins; C490895:GAB2 protein, human; D026502:LDL-Receptor Related Proteins; D026901:Membrane Transport Proteins; C512806:NIN protein, human; D009687:Nuclear Proteins; C102582:SORL1 protein, human