title: Psychosis and severe rhabdomyolysis associated with synthetic cannabinoid use: A case report.
abstract: BACKGROUND
  Synthetic cannabinoid (SC) or "spice" refers to a variety of herbal/chemical mixtures, which mimic the effects of marijuana. They are generally marked as "herbal incense" and best known by the brand names of "K2," "spice," "aroma," "Mr. Nice Guy" and "dream." Little data are available on the psychopathological and physical effects of SC.
  
  
  METHODS
  We reported on a 23-year-old man without prior psychiatric history who developed acute psychosis and severe rhabdomyolysis (creatine phosphokinase [CPK]: 44,300 UI/L) associated with "Mr. Nice Guy" consumption. To our knowledge, this is the first case report of severe rhabdomyolysis associated with SC use in the U.S.
  
  
  CONCLUSIONS
  Physicians should be aware of the possibility of new-onset psychotic symptoms and rhabdomyolysis in patients that use SC.
authors.affiliation: University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Dante
authors.initials: D
authors.lastname: Durand
authors.affiliation: University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Leticia L
authors.initials: LL
authors.lastname: Delgado
authors.affiliation: University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Dhizarah Matus
authors.initials: DM
authors.lastname: de la Parra-Pellot
authors.affiliation: Universidad del Valle, Cali, Colombia.
authors.forename: Diana
authors.initials: D
authors.lastname: Nichols-Vinueza
mesh_terms: D000328:Adult; D002186:Cannabinoids / Q000494:pharmacology*; D006801:Humans; D013287:Illicit Drugs / Q000494:pharmacology*; D008297:Male; D011605:Psychoses, Substance-Induced / Q000150:complications*; D012206:Rhabdomyolysis / Q000139:chemically induced* / Q000150:complications*; D055815:Young Adult
chemical_list: D002186:Cannabinoids; D013287:Illicit Drugs
keywords: Creatine Phosphokinase (CPK); Psychosis; Rhabdomyolysis; Spice; Synthetic Cannabinoids (SC)