title: [Biomaterials in bone repair].
abstract: In orthopedics, traumatology, and craniofacial surgery, biomaterials should meet the clinical demands of bone that include shape, size and anatomical location of the defect, as well as the physiological load-bearing stresses. Biomaterials are metals, ceramics, plastics or materials of biological origin. In the treatment of large defects, metallic endoprostheses or bone grafts are employed, whereas ceramics in the case of small defects. Plastics are employed on the artificial joint surfaces, in the treatment of vertebral compression fractures, and as biodegradable screws and plates. Porosity, bioactivity, and identical biomechanics to bone are fundamental for achieving a durable, well-bonded, interface between biomaterial and bone. In the case of severe bone treatments, biomaterials should also imply an option to add biologically active substances.
authors.affiliation: Turun yliopisto, TCBC.
authors.forename: Mervi
authors.initials: M
authors.lastname: Puska
authors.forename: Allan J
authors.initials: AJ
authors.lastname: Aho
authors.forename: Pekka K
authors.initials: PK
authors.lastname: Vallittu
mesh_terms: D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D001842:Bone and Bones / Q000601:surgery*; D002516:Ceramics; D006801:Humans; D008670:Metals; D057909:Orthognathic Surgery / Q000295:instrumentation*; D009985:Orthopedics; D010969:Plastics; D016062:Porosity; D019736:Prostheses and Implants; D014194:Traumatology / Q000295:instrumentation*
chemical_list: D001672:Biocompatible Materials; D008670:Metals; D010969:Plastics