title: [Application of 1% lauromacrogol in the treatment of facial refractory hemangioma and vascular malformations].
abstract: OBJECTIVE
  To investigate the clinical effect of 1% lauromacrogol for the treatment of facial refractory hemangioma and vascular malformation.
  
  
  METHODS
  From Sept 2009 to Nov 2011, 55 patients (20 male, 35 female, 1 month to 30 years) with different types of facial hemangiorwa and vascular malformation about 1.0 cm x (0. 5-5.0) cm x 10.0 cm in size, underwent 1% lauromacrogol intratumor injection therapy. Generally, the injection dose, concentration, frequency were determined by the age of the patients, the volume and depth of the lesion. The dose was limited to 10 mg every time. The injection interval is 14 weeks.
  
  
  RESULTS
  After followed up for 3-16 months, 41 cases were cured, 9 cases were greatly improved, and 5 were partially improved. Skin necrosis happened in only 2 cases.
  
  
  CONCLUSIONS
  Lauromacrogol is safe, simple and effective as a sderosing agent for the treatment of facial refractory hemangioma and vascular malformation. It provides a new and alternative way for the treatment of facial refractory hemangioma and vascular malformation.
authors.affiliation: First Affiliated Hosipital of Anhui Medical University, Hefei 230032, China.
authors.forename: Yin
authors.initials: Y
authors.lastname: Wang
authors.forename: Fei
authors.initials: F
authors.lastname: Zhu
authors.forename: Jin-long
authors.initials: JL
authors.lastname: Ning
authors.forename: Xiao-jing
authors.initials: XJ
authors.lastname: Li
authors.forename: Ye
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005145:Face / Q000098:blood supply*; D005153:Facial Neoplasms / Q000188:drug therapy*; D005260:Female; D006391:Hemangioma / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D015552:Injections, Intralesional; D008297:Male; D011092:Polyethylene Glycols / Q000008:administration & dosage*; D012597:Sclerosing Solutions / Q000008:administration & dosage*; D054079:Vascular Malformations / Q000188:drug therapy*; D055815:Young Adult
chemical_list: D012597:Sclerosing Solutions; D011092:Polyethylene Glycols