title: The relationship between morning hypertension and sleep quality in patients with obstructive sleep apnea syndrome.
abstract: This study aimed to investigate the prevalence of abnormal diurnal blood pressure (BP) profiles in patients with obstructive sleep apnea syndrome (OSAS) in relation to the data of a sleep study. Total 103 patients newly diagnosed with OSAS underwent overnight polysomnography and 24-hour ambulatory BP measurements. Patients without morning or nocturnal hypertension (control group), patients with morning hypertension but not nocturnal hypertension (surge-type group), and patients with both morning and nocturnal hypertension (sustained-type group) were compared. Morning hypertension was present in 54 patients (16 surge-type and 38 sustained-type). The apnea-hypopnea index and sleep efficiency were higher and lower, respectively, in the sustained-type group than in the other groups. Slow-wave sleep incidence was significantly lower in the sustained-type and surge-type groups than in the control group. These results suggest that approximately half the OSAS patients displayed morning hypertension, the sustained-type being more common than the surge-type. Poor sleep quality plays an important role in the pathogenesis of morning hypertension in both the sustained- and the surge-type group.
authors.affiliation: Department of Internal Medicine, Mitsubishi Mihara Hospital, Mihara, Japan. fm2khdz3@384.jp
authors.forename: Nobuo
authors.initials: N
authors.lastname: Sasaki
authors.forename: Ryoji
authors.initials: R
authors.lastname: Ozono
authors.forename: Ryo
authors.initials: R
authors.lastname: Yamauchi
authors.forename: Kazushi
authors.initials: K
authors.lastname: Teramen
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Edahiro
authors.forename: Kiyomi
authors.initials: K
authors.lastname: Ishii
authors.forename: Ayako
authors.initials: A
authors.lastname: Seto
authors.forename: Yasuki
authors.initials: Y
authors.lastname: Kihara
mesh_terms: D000328:Adult; D000368:Aged; D018660:Blood Pressure Monitoring, Ambulatory; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D012307:Risk Factors; D012890:Sleep / Q000502:physiology; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000503:physiopathology* / Q000523:psychology; D012893:Sleep Wake Disorders / Q000150:complications / Q000503:physiopathology