title: Dynamics of clinical symptoms in patients with scrub typhus.
abstract: The clinical manifestations and complications of scrub typhus are variable. Few studies have examined the timeline of clinical symptoms after the appropriate antimicrobial agents have been administered. The most prevalent clinical manifestations are fever and cough, followed by headache, myalgia, eschar, skin rash, and nausea. Systemic symptoms are most severe during the early stages of illness (i.e., the first 5 days), but resolve slowly within 2 weeks. The associated skin rash is most severe during the first 8 days of infection, but it resolves slowly within 21 days.
authors.affiliation: Department of Internal Medicine, Wonkwang University College of Medicine, Iksan, Republic of Korea.
authors.forename: Jae-Hoon
authors.initials: JH
authors.lastname: Lee
authors.forename: Ju-Hyung
authors.initials: JH
authors.lastname: Lee
authors.forename: Kyung Min
authors.initials: KM
authors.lastname: Chung
authors.forename: Eu Suk
authors.initials: ES
authors.lastname: Kim
authors.forename: Yee Gyung
authors.initials: YG
authors.lastname: Kwak
authors.forename: Chisook
authors.initials: C
authors.lastname: Moon
authors.forename: Chang-Seop
authors.initials: CS
authors.lastname: Lee
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D004064:Digestive System / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009420:Nervous System / Q000473:pathology; D012137:Respiratory System / Q000473:pathology; D012612:Scrub Typhus / Q000150:complications / Q000188:drug therapy* / Q000473:pathology*; D012720:Severity of Illness Index; D013997:Time Factors; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents