title: Prevalence of pain syndromes, mood conditions, and asthma in adolescents and young women with endometriosis.
abstract: OBJECTIVE
  Adult women with endometriosis are often diagnosed with comorbid pain, mood, and autoimmune conditions. This study aims to describe the occurrence of pain syndromes, mood conditions, and asthma in adolescents and young women with endometriosis evaluated at our medical center.
  
  
  METHODS
  Retrospective review of medical records.
  
  
  METHODS
  Department of Obstetrics and Gynecology at a tertiary referral center.
  
  
  METHODS
  138 adolescents/young women who were less than age 24 years at the time of their initial visit at our medical center, and whose surgical diagnosis of endometriosis was made at our institution or by outside institutions by the age of 21.
  
  
  METHODS
  None.
  
  
  METHODS
  Prevalence of comorbid pain syndromes (defined as interstitial cystitis, irritable bowel syndrome, chronic headaches, chronic low back pain, vulvodynia, fibromyalgia, temporomandibular joint disease, and chronic fatigue syndrome), mood conditions (defined as depression and anxiety), and asthma.
  
  
  RESULTS
  Comorbid pain syndromes were found in 77 (56%) women, mood conditions in 66 (48%) women, and asthma in 31 (26%) women. Comparing endometriosis patients with and without comorbid pain syndromes, no differences were found in age at time of diagnosis, endometriosis symptoms, and endometriosis stage. Patients with comorbid pain syndromes were more likely to report mood conditions (62% vs 30% respectively, P < .001) and smoking (31% vs 10% respectively, P = .003), underwent more surgeries for endometriosis (median of 2 [range, 1-7] vs 1 [range, 1-5], P < .005), and were more likely to undergo appendectomy or cholecystectomy (30% vs 13%, P = .02).
  
  
  CONCLUSIONS
  Comorbid pain syndromes, mood conditions and asthma are common in adolescents and young women with endometriosis.
authors.affiliation: Department of Obstetrics and Gynecology, University of Michigan Health System, Ann Arbor, Michigan 48109, USA. noam_yossi@yahoo.com
authors.forename: Noam
authors.initials: N
authors.lastname: Smorgick
authors.forename: Courtney A
authors.initials: CA
authors.lastname: Marsh
authors.forename: Sawsan
authors.initials: S
authors.lastname: As-Sanie
authors.forename: Yolanda R
authors.initials: YR
authors.lastname: Smith
authors.forename: Elisabeth H
authors.initials: EH
authors.lastname: Quint
mesh_terms: D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000453:epidemiology*; D001249:Asthma / Q000453:epidemiology*; D015897:Comorbidity; D018856:Cystitis, Interstitial / Q000453:epidemiology; D003863:Depression / Q000453:epidemiology*; D004715:Endometriosis / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D015673:Fatigue Syndrome, Chronic / Q000453:epidemiology; D005260:Female; D005356:Fibromyalgia / Q000453:epidemiology; D006261:Headache / Q000453:epidemiology; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000453:epidemiology; D017116:Low Back Pain / Q000453:epidemiology; D010146:Pain / Q000453:epidemiology*; D015995:Prevalence; D012189:Retrospective Studies; D012907:Smoking / Q000453:epidemiology; D013705:Temporomandibular Joint Disorders / Q000453:epidemiology; D056650:Vulvodynia / Q000453:epidemiology; D055815:Young Adult