title: [Evaluation of myocardial energy metabolism by 31 P-magnetic resonance spectroscopy in patients with hypertrophic cardiomyopathy versus healthy individuals].
abstract: OBJECTIVE
  To estimate the left ventricular (LV) energy index from the data of 31P-magnetic resonance spectroscopy (31P-MRS) in patients with hypertrophic cardiomyopathy (HCM) versus healthy individuals.
  
  
  METHODS
  The investigation included 46 persons, including 30 healthy volunteers (Group 1) without cardiovascular diseases and 16 patients with HCM (Group 2). All the persons underwent cardiac magnetic resonance imaging (MRI) and 31P-MRS using a high-field Achieva 3T TX MRI scanner (Philips, Netherlands). ISIS location and adiabatic pulse with iterative shimming were used to collect data.
  
  
  RESULTS
  The PC/ATP energy index (a phosphocreatine to adenosine triphosphate ratio) was employed to evaluate myocardial energy metabolism in the patients with HCM. The PC/ATP index was 2.08 +/- 0.35 in Group 1 and 1.32 +/- 3.3 in Group 2 (p < 0.05).
  
  
  CONCLUSIONS
  31P-MRS may be used to determine the myocardial energy metabolism in patients with HCM.
authors.forename: V V
authors.initials: VV
authors.lastname: Mazaev
authors.forename: O V
authors.initials: OV
authors.lastname: Stukalova
authors.forename: S K
authors.initials: SK
authors.lastname: Ternovoĭ
authors.forename: I E
authors.initials: IE
authors.lastname: Chazova
mesh_terms: D002312:Cardiomyopathy, Hypertrophic / Q000378:metabolism*; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000378:metabolism*; D010759:Phosphorus Isotopes; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D010759:Phosphorus Isotopes