title: Determining target engagement in living systems.
authors.affiliation: Abide Therapeutics, San Diego, California, USA.
authors.forename: Gabriel M
authors.initials: GM
authors.lastname: Simon
authors.forename: Micah J
authors.initials: MJ
authors.lastname: Niphakis
authors.forename: Benjamin F
authors.initials: BF
authors.lastname: Cravatt
mesh_terms: D000818:Animals; D054316:Biomarkers, Pharmacological / Q000737:chemistry / Q000378:metabolism*; D018929:Cell Culture Techniques; D002853:Chromatography, Liquid; D004353:Drug Evaluation, Preclinical; D006801:Humans; D047468:Immunoprecipitation; D015335:Molecular Probes / Q000737:chemistry / Q000378:metabolism*; D058990:Molecular Targeted Therapy; D040081:Protein Array Analysis; D019275:Radiopharmaceuticals; D053719:Tandem Mass Spectrometry; D054928:Validation Studies as Topic
chemical_list: D054316:Biomarkers, Pharmacological; D015335:Molecular Probes; D019275:Radiopharmaceuticals