title: ROS links glucose metabolism to breast cancer stem cell and EMT phenotype.
abstract: Cancer stem cells display an epithelial-mesenchymal transition phenotype and are resistant to current therapies. In this issue of Cancer Cell, Dong and colleagues demonstrate that these phenotypes in basal-like breast cancer are promoted by a metabolic switch to glucose metabolism, resulting in decreased reactive oxygen species levels.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Schieber
authors.forename: Navdeep S
authors.initials: NS
authors.lastname: Chandel