title: Target validation using chemical probes.
authors.affiliation: Worldwide Medicinal Chemistry at Pfizer, Cambridge, Massachusetts, USA. mark.bunnage@pfizer.com
authors.forename: Mark E
authors.initials: ME
authors.lastname: Bunnage
authors.forename: Eugene L Piatnitski
authors.initials: EL
authors.lastname: Chekler
authors.forename: Lyn H
authors.initials: LH
authors.lastname: Jones
mesh_terms: D054316:Biomarkers, Pharmacological / Q000737:chemistry* / Q000378:metabolism; D002463:Cell Membrane Permeability; D055808:Drug Discovery; D004353:Drug Evaluation, Preclinical; D006801:Humans; D015335:Molecular Probes / Q000737:chemistry* / Q000378:metabolism; D058990:Molecular Targeted Therapy; D013329:Structure-Activity Relationship; D054928:Validation Studies as Topic
chemical_list: D054316:Biomarkers, Pharmacological; D015335:Molecular Probes