title: First case report of acute hemorrhagic leukoencephalitis following Plasmodium vivax infection.
abstract: Acute hemorrhagic leukoencephalitis (AHLE, Hurst's disease) is a rare hyperacute variant of acute disseminated encephalomyelitis (ADEM) characterized by severe, rapidly progressive clinical illness and hemorrhagic necrosis of white matter. Like ADEM, it is often preceded by viral illness or vaccination. Plasmodium vivax infection is usually uncomplicated and non-fatal with only a handful of reports of central nervous system complications. In this article, we report a previously unknown association between AHLE and P. vivax infection.
authors.affiliation: Department of Radio diagnosis, JN Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
authors.forename: V
authors.initials: V
authors.lastname: Venugopal
authors.forename: M
authors.initials: M
authors.lastname: Haider
mesh_terms: D001769:Blood / Q000469:parasitology; D001921:Brain / Q000000981:diagnostic imaging; D004453:Echoencephalography; D006801:Humans; D004684:Leukoencephalitis, Acute Hemorrhagic / Q000175:diagnosis* / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D016780:Malaria, Vivax / Q000150:complications* / Q000175:diagnosis*; D008297:Male; D008853:Microscopy; D055815:Young Adult