title: Two new bromophenols with radical scavenging activity from marine red alga Symphyocladia latiuscula.
abstract: Chemical investigation of a Chinese collection of marine red alga Symphyocladia latiuscula yielded two new highly brominated phenols. The structures of the new compounds were elucidated by detailed spectroscopic analysis, including HRMS, 1D and 2D NMR and MS methods. Compounds 1 and 2 were evaluated for radical scavenging capability by 1,1-diphenyl-2-picrylhydrazuyl (DPPH) radical with the IC50 value of 14.5 and 20.5 μg/mL, respectively.
authors.affiliation: School of Ocean Sciences, China University of Geosciences, Beijing 100083, China. xuxl@cugb.edu.cn
authors.forename: Xiuli
authors.initials: X
authors.lastname: Xu
authors.forename: Liyuan
authors.initials: L
authors.lastname: Yin
authors.forename: Lijie
authors.initials: L
authors.lastname: Gao
authors.forename: Junhai
authors.initials: J
authors.lastname: Gao
authors.forename: Junhui
authors.initials: J
authors.lastname: Chen
authors.forename: Jingxi
authors.initials: J
authors.lastname: Li
authors.forename: Fuhang
authors.initials: F
authors.lastname: Song
mesh_terms: D001713:Biphenyl Compounds / Q000737:chemistry; D001966:Bromine / Q000737:chemistry; D002681:China; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D020128:Inhibitory Concentration 50; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010851:Picrates / Q000737:chemistry; D000461:Rhodophyta / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D001713:Biphenyl Compounds; D016166:Free Radical Scavengers; D010636:Phenols; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl; D001966:Bromine