title: Palladium-catalyzed intermolecular dehydrogenative aminohalogenation of alkenes under molecular oxygen: an approach to brominated enamines.
abstract: A novel and efficient palladium-catalyzed dehydrogenative aminohalogenation of alkenes with molecular oxygen as the sole oxidant has been developed. This protocol provides a valuable synthetic tool for the assembly of a wide range of brominated enamines under mild conditions, with unprecedented stereoselectivity and exceptional functional group tolerance. This attractive route for the synthesis of brominated enamines is of great significance due to the products' versatile reactivity for further transformations.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, P.R. China.
authors.forename: Xiaochen
authors.initials: X
authors.lastname: Ji
authors.forename: Huawen
authors.initials: H
authors.lastname: Huang
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D006865:Hydrogenation; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000475:Alkenes; D000588:Amines; D009942:Organometallic Compounds; D010165:Palladium; D010100:Oxygen