title: Peltate glandular trichomes of Colquhounia coccinea var. mollis harbor a new class of defensive sesterterpenoids.
abstract: A new class of unique sesterterpenoids, colquhounoids A-C (1-3), were identified from the peltate glandular trichomes of Colquhounia coccinea var. mollis (Lamiaceae) through precise laser-microdissection coupled with UPLC/MS/MS and spectroscopic analyses and X-ray diffraction. Very interestingly, their structural features and defensive function are closely related to leucosceptroid-class sesterterpenoids harbored by the glandular trichomes of another Lamiaceae taxon, Leucosceptrum canum, even though this is morphologically distinct and taxonomically distant.
authors.affiliation: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China.
authors.forename: Chun-Huan
authors.initials: CH
authors.lastname: Li
authors.forename: Shu-Xi
authors.initials: SX
authors.lastname: Jing
authors.forename: Shi-Hong
authors.initials: SH
authors.lastname: Luo
authors.forename: Wei
authors.initials: W
authors.lastname: Shi
authors.forename: Juan
authors.initials: J
authors.lastname: Hua
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.forename: Xiao-Nian
authors.initials: XN
authors.lastname: Li
authors.forename: Bernd
authors.initials: B
authors.lastname: Schneider
authors.forename: Jonathan
authors.initials: J
authors.lastname: Gershenzon
authors.forename: Sheng-Hong
authors.initials: SH
authors.lastname: Li
mesh_terms: D000818:Animals; D018360:Crystallography, X-Ray; D005247:Feeding Behavior / Q000187:drug effects; D019686:Lamiaceae / Q000737:chemistry*; D008968:Molecular Conformation; D015394:Molecular Structure; D009036:Moths / Q000187:drug effects; D019906:Nuclear Magnetic Resonance, Biomolecular; D018515:Plant Leaves / Q000737:chemistry; D054830:Sesterterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018411:Spodoptera / Q000187:drug effects; D053719:Tandem Mass Spectrometry
chemical_list: D054830:Sesterterpenes; C583549:colquhounoid A; C583550:colquhounoid B; C583548:colquhounoid C