title: Spontaneous vesicoureteral reflux resolution in children: A ten-year single-centre experience.
abstract: OBJECTIVE
  To evaluate the spontaneous resolution rate in infants and young children with vesicoureteral reflux (VUR).
  
  
  METHODS
  Paediatric patients with VUR treated in our hospital from January 2000 to December 2010 were retrospectively analyzed. Only patients with pretreatment and follow-up voiding cystourethrogram were included into the study. Treatment success was defined as complete VUR resolution.
  
  
  RESULTS
  The resolution rate for infants less than 1 year of age was 38.6% (17 of 44 renal units). Renal units with mild-moderate VUR (I-III) had a resolution rate of 40% (12 of 30 renal units) compared to 35.7% (5 of 14 renal units) with severe grade (IV-V) VUR. The resolution rate for children over 1 year of age was 39,1% (9 of 23 renal units). Renal units with mild-moderate VUR (I-III) had a resolution rate of 42.9% (9 of 21 renal units) compared to 0% (0 of 2 renal units) with severe grade (IV-V) VUR.
  
  
  CONCLUSIONS
  Infants less than 1 year of age with nonsymptomatic, mild, moderate or severe VUR have a spontaneous resolution rate of more than 35% and therefore should receive a primary conservative therapy. Children over 1 year of age with nonsymptomatic mild-moderate VUR (I-III) have a spontaneous resolution rate of about 40% and should receive primary conservative treatment as well.
authors.affiliation: Department of Pediatric Surgery, University Children's Hospital Greifswald, Germany.
authors.forename: Peer
authors.initials: P
authors.lastname: Wildbrett
authors.forename: Mandy
authors.initials: M
authors.lastname: Schwebs
authors.forename: J Rgen
authors.initials: JR
authors.lastname: Abel
authors.forename: Holger
authors.initials: H
authors.lastname: Lode
authors.forename: Winfried
authors.initials: W
authors.lastname: Barthlen
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D005544:Forecasting; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012075:Remission, Spontaneous; D012189:Retrospective Studies; D014563:Urodynamics / Q000502:physiology*; D014718:Vesico-Ureteral Reflux / Q000503:physiopathology*