title: Long-term quality of life of liver transplant recipients beyond 60 years of age.
abstract: Due to ameliorated surgery as well as better immunosuppression, the recipient age after liver transplantation has been extended over the past years. This study aimed to investigate the health related quality of life after liver transplantation in recipients beyond 60 years of age. The SF-36 was used to evaluate the recipients' health-related quality of life as standardized tool. It comprises 36 items that are attributed to 8 subscales attributed to 2 components: the physical component score and the mental component score. Differences in the health-related quality of life between the included aged recipients and age-matched general population as well as among female and male recipients. Aged recipients showed significantly lower scores in physical functioning (29 vs. 76, p = 0.001), role physical (42 vs. 73, p = 0.003), bodily pain (34 vs. 71, p = 0.003), general health (28 vs. 59, p = 0.001), vitality (25 vs. 61, p = 0.001), social functioning (36 vs. 87, p =0.001), role emotional (46 vs. 89, p = 0.001) as well as the physical component score (28 vs. 76, p = 0.001). Aged female recipients showed lower results as compared to males in social functioning, physical functioning, role physical, and social functioning (p = 0.03 respectively) but comparable results in the remaining. Quality of life seems to be an issue among aged recipients and should be assessed on a regular basis.
authors.affiliation: Division for General Surgery, Department of Surgery, Medical University of Graz, Graz, Austria.
authors.forename: G
authors.initials: G
authors.lastname: Werkgartner
authors.forename: D
authors.initials: D
authors.lastname: Wagner
authors.forename: S
authors.initials: S
authors.lastname: Manhal
authors.forename: A
authors.initials: A
authors.lastname: Fahrleitner-Pammer
authors.forename: H J
authors.initials: HJ
authors.lastname: Mischinger
authors.forename: M
authors.initials: M
authors.lastname: Wagner
authors.forename: R
authors.initials: R
authors.lastname: Grgic
authors.forename: R E
authors.initials: RE
authors.lastname: Roller
authors.forename: D
authors.initials: D
authors.lastname: Kniepeiss
mesh_terms: D000367:Age Factors; D000368:Aged; D000375:Aging / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D006304:Health Status; D006801:Humans; D008107:Liver Diseases / Q000523:psychology / Q000601:surgery*; D016031:Liver Transplantation / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011788:Quality of Life; D011795:Surveys and Questionnaires; D013997:Time Factors