title: Recording dendritic ion channel properties and function from cortical neurons.
abstract: Dendrites emerging from the cell bodies of neurons receive the majority of synaptic inputs. They possess a plethora of ion channels that are essential for the processing of these synaptic signals. To fully understand how dendritic ion channels influence neuronal information processing, various patch-clamp techniques that allow electrophysiological recordings to be made directly from dendrites have been developed. In this chapter, I describe one such method that is suitable for making electrophysiological recordings from the apical dendrites of hippocampal and cortical pyramidal neurons.
authors.affiliation: Department of Pharmacology, UCL School of Pharmacy, University College London, London, UK.
authors.forename: Mala M
authors.initials: MM
authors.lastname: Shah
mesh_terms: D003712:Dendrites / Q000378:metabolism*; D055724:Electrophysiological Phenomena; D007473:Ion Channels / Q000378:metabolism*; D009415:Nerve Net / Q000166:cytology / Q000378:metabolism / Q000502:physiology; D018408:Patch-Clamp Techniques / Q000295:instrumentation / Q000379:methods*; D017966:Pyramidal Cells / Q000166:cytology* / Q000378:metabolism / Q000502:physiology*
chemical_list: D007473:Ion Channels