title: [Differential-diagnostic features of combined periapical lesions].
abstract: The paper describes specific correlation of the clinical and molecular pathogenic features in various types of combined periapical lesions. Endodontic apical lesions combined with periodontal disease are characterized by specific radiological signs, shifts in oral fluid physical and chemical properties, the disruption of nitrogen metabolism, increased iron concentration, collagen disruption and impaired concentration ratio of calcium and phosphorous. General depression of immunoglobulin synthesis and increased concentration of cortisol and estradiol in oral fluid are also typical features of combined periapical lesions.
authors.forename: E M
authors.initials: EM
authors.lastname: Gil'miiarov
authors.forename: V P
authors.initials: VP
authors.lastname: Tlustenko
authors.forename: V M
authors.initials: VM
authors.lastname: Radomskaia
authors.forename: A V
authors.initials: AV
authors.lastname: Babichev
authors.forename: E S
authors.initials: ES
authors.lastname: Golovina
authors.forename: E A
authors.initials: EA
authors.lastname: Sazonova
authors.forename: K I
authors.initials: KI
authors.lastname: Kolesova
authors.forename: A N
authors.initials: AN
authors.lastname: Azizov
mesh_terms: D002118:Calcium / Q000032:analysis; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004958:Estradiol / Q000032:analysis; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis / Q000096:biosynthesis; D008297:Male; D010485:Periapical Periodontitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism; D010519:Periodontium / Q000276:immunology / Q000378:metabolism; D010758:Phosphorus / Q000032:analysis; D011859:Radiography; D012463:Saliva / Q000737:chemistry / Q000378:metabolism
chemical_list: D007136:Immunoglobulins; D010758:Phosphorus; D004958:Estradiol; D002118:Calcium; D006854:Hydrocortisone