title: Relationship between sexual function and quality of life in obese persons seeking weight reduction.
abstract: OBJECTIVE
  This study investigated sexual functioning in persons with obesity and seeking weight loss, and the associations of sexual functioning with relevant demographic and clinical variables as well as quality of life were investigated.
  
  
  METHODS
  Participants were enrolled in a two-year randomized clinical trial. Participants were obese and had at least two components of metabolic syndrome. Male and female sexual functioning was assessed by the International Index of Erectile Function (IIEF) and the Female Sexual Function Index (FSFI) respectively.
  
  
  RESULTS
  The rate of female sexual dysfunction was 29%. The rate of erectile dysfunction (ED) was 45%. Of the characteristics considered, FSD was associated with age (P = 0.002). ED was significantly associated with age and physical functioning (both P < 0.01).
  
  
  CONCLUSIONS
  A large minority of patients with obesity reported sexual dysfunction. The occurrence of sexual dysfunction was associated with age, but, surprisingly, not weight-related comorbidities. This may be the result of the nature of the study sample or the methods used to administer the questionnaires that assessed sexual functioning.
authors.affiliation: Department of Psychiatry, Center for Weight and Eating Disorders, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Statistics, North Carolina State University, Raleigh, North Carolina, USA.
authors.forename: Reneé H
authors.initials: RH
authors.lastname: Moore
authors.forename: David B
authors.initials: DB
authors.lastname: Sarwer
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Lavenberg
authors.forename: Ilana B
authors.initials: IB
authors.lastname: Lane
authors.forename: Joanna L
authors.initials: JL
authors.lastname: Evans
authors.forename: Sheri
authors.initials: S
authors.lastname: Volger
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Wadden
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001794:Blood Pressure; D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood; D003863:Depression / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000503:physiopathology*; D011788:Quality of Life; D012737:Sex Factors; D012735:Sexual Dysfunction, Physiological / Q000209:etiology / Q000503:physiopathology*; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D014280:Triglycerides / Q000097:blood; D055105:Waist Circumference; D015431:Weight Loss
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D014280:Triglycerides