title: Influence of olive oil press cakes on Shiitake culinary-medicinal mushroom, lentinus edodes (Berk.) singer (higher basidiomycetes) fruiting bodies production and effect of their crude polysaccharides on CCRF-CEM cell proliferation.
abstract: Lentinus edodes (Berk.) Singer fruiting bodies were cultivated on substrates composed of beech sawdust, wheat bran, and calcium sulfate hemihydrate (gypsum), containing different proportions of olive oil press cakes (OOPC). We determined the influence of OOPC on fruiting bodies production and proliferation of CCRF-CEM leukemia cells. A negative influence of OOPC on mycelia growth and maturation was noticed. When growth medium contained 80% OOPC, fruiting bodies ceased forming. To investigate the cytotoxicity on CCRF-CEM cells in vitro, cells were treated with crude polysaccharides extracted from L. edodes fruiting bodies. Also in this case a negative correlation between OOPC content and cytotoxicity was found.
authors.affiliation: Institue for Natural Sciences, Ljubljana, Slovenia. andrej.gregori@gmail.com
authors.forename: Andrej
authors.initials: A
authors.lastname: Gregori
authors.forename: Nadine
authors.initials: N
authors.lastname: Kretschmer
authors.forename: Susanne
authors.initials: S
authors.lastname: Wagner
authors.forename: Herbert
authors.initials: H
authors.lastname: Boechzelt
authors.forename: Dusan
authors.initials: D
authors.lastname: Klinar
authors.forename: Rudolf
authors.initials: R
authors.lastname: Bauer
authors.forename: Franc
authors.initials: F
authors.lastname: Pohleven
mesh_terms: D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects*; D019649:Food Industry; D048690:Fruiting Bodies, Fungal / Q000737:chemistry; D006801:Humans; D007220:Industrial Waste; D000069463:Olive Oil; D010938:Plant Oils; D011134:Polysaccharides / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D020942:Shiitake Mushrooms / Q000254:growth & development*; D014866:Waste Products
chemical_list: D007220:Industrial Waste; D000069463:Olive Oil; D010938:Plant Oils; D011134:Polysaccharides; D014866:Waste Products