title: Clinical, histological, and immunohistochemical features of a mandibular metastasis from a primary cardiac angiosarcoma.
abstract: Primary cardiac angiosarcoma is an extremely rare malignant tumor. Distant metastases are common at the time of diagnosis but have never been reported in the jaw. A 45-year-old female patient with primary cardiac angiosarcoma was referred for dental care due to pain in the mandibular alveolar ridge. Oral examination revealed a red-violet lesion that was soft on palpation and had been present for 3 months. Histological analysis confirmed the diagnosis of metastatic cardiac angiosarcoma. The patient died of multiple metastases.
authors.affiliation: Department of Stomatology and Oral Pathology, School of Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil. clarissa_pf@hotmail.com
authors.forename: Clarissa Pessoa
authors.initials: CP
authors.lastname: Fernandes
authors.forename: Francisco Artur Forte
authors.initials: FA
authors.lastname: Oliveira
authors.forename: Fábio Wildson Gurgel
authors.initials: FW
authors.lastname: Costa
authors.forename: Régia Maria do Socorro Vidal
authors.initials: RM
authors.lastname: Patrocínio
authors.forename: Mário Rogério Lima
authors.initials: MR
authors.lastname: Mota
authors.forename: Ana Paula Negreiros
authors.initials: AP
authors.lastname: Nunes Alves
authors.forename: Fabrício Bitu
authors.initials: FB
authors.lastname: Sousa
mesh_terms: D018952:Antigens, CD34 / Q000032:analysis; D017809:Fatal Outcome; D005260:Female; D006338:Heart Neoplasms / Q000473:pathology*; D006394:Hemangiosarcoma / Q000473:pathology / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis / Q000473:pathology; D008339:Mandibular Neoplasms / Q000473:pathology / Q000556:secondary*; D008875:Middle Aged; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000032:analysis
chemical_list: D018952:Antigens, CD34; D019408:Platelet Endothelial Cell Adhesion Molecule-1