title: Prevalence of oral human papilloma virus in healthy individuals in East azerbaijan province of iran.
abstract: BACKGROUND
  Human papilloma virus causes benign and malignant abnormalities in different part of the body. The link between high risk types of HPV and some anogenital and aerodigestive tract cancer is well established. Oral HPV infection plays a role in developing oropharyngeal squamous cell carcinoma. We studied the prevalence of oral HPV in healthy individuals and its relative risk factors.
  
  
  METHODS
  Saliva samples of 114 healthy subjects were collected for HPV DNA analysis. Volunteers completed questionnaires and signed a written consent. For data analysis descriptive statistic, chi square test and odds ratio was used.
  
  
  RESULTS
  The frequency of oral HPV in healthy individuals was 6.1 %(seven participant).The most frequent type was HPV-18 in five of them. HPV-6 and HPV-66 each was detected in one case. Relation of oral HPV positivity to demographic features and risk factors was not statistically significant.
  
  
  CONCLUSIONS
  The prevalence of oral HPV infection in our community is the same as many other communities of developing countries, stressing that HPV-18 were the dominant type.
authors.affiliation: Medical Oncology Department, National Research Institute of TB and Lung Disease, Masih Daneshvari Hospital, Tehran, Iran.
authors.forename: Sharareh
authors.initials: S
authors.lastname: Seifi
authors.forename: Iraj
authors.initials: I
authors.lastname: Asvadi Kermani
authors.forename: Roya
authors.initials: R
authors.lastname: Dolatkhah
authors.forename: Atabak
authors.initials: A
authors.lastname: Asvadi Kermani
authors.forename: Ebrahim
authors.initials: E
authors.lastname: Sakhinia
authors.forename: Mohammad
authors.initials: M
authors.lastname: Asgarzadeh
authors.forename: Saeed
authors.initials: S
authors.lastname: Dastgiri
authors.forename: Ayoub
authors.initials: A
authors.lastname: Ebrahimi
authors.forename: Arezou
authors.initials: A
authors.lastname: Asghari Haggi
authors.forename: Mahsa
authors.initials: M
authors.lastname: Nadri
authors.forename: Touraj
authors.initials: T
authors.lastname: Asvadi Kermani
keywords: Human Papilloma Virus (HPV); Oral Cancer; Saliva