title: O-heterocyclic embeurekols from Embellisia eureka, an endophyte of Cladanthus arabicus.
abstract: Three new polyketides ((-)-1, (+)-1, and 2) were isolated from the EtOAc extract of the fungus Embellisia eureka, an endophyte of the Moroccan plant Cladanthus arabicus (Asteraceae). The structures of these new compounds were determined on the basis of one- and two-dimensional NMR spectroscopy as well as by high-resolution mass spectrometry. The absolute configurations of (-)-1, (+)-1, and 2 were determined by TDDFT ECD calculations of solution conformers, online HPLC-ECD analysis, and the modified Mosher method.
authors.affiliation: Institut für Pharmazeutische Biologie und Biotechnologie, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, Geb. 26.23, 40225 Düsseldorf, Germany.
authors.forename: Weaam
authors.initials: W
authors.lastname: Ebrahim
authors.forename: Amal H
authors.initials: AH
authors.lastname: Aly
authors.forename: Attila
authors.initials: A
authors.lastname: Mándi
authors.forename: Victor
authors.initials: V
authors.lastname: Wray
authors.forename: El Mokhtar
authors.initials: el M
authors.lastname: Essassi
authors.forename: Tarik
authors.initials: T
authors.lastname: Ouchbani
authors.forename: Rachid
authors.initials: R
authors.lastname: Bouhfid
authors.forename: Wenhan
authors.initials: W
authors.lastname: Lin
authors.forename: Peter
authors.initials: P
authors.lastname: Proksch
authors.forename: Tibor
authors.initials: T
authors.lastname: Kurtán
authors.forename: Abdessamad
authors.initials: A
authors.lastname: Debbab
mesh_terms: D000528:Alternaria / Q000737:chemistry* / Q000502:physiology*; D019659:Asteraceae / Q000382:microbiology*; D060026:Endophytes / Q000737:chemistry* / Q000502:physiology*; D006571:Heterocyclic Compounds / Q000737:chemistry* / Q000302:isolation & purification*; D008958:Models, Molecular; D008968:Molecular Conformation
chemical_list: D006571:Heterocyclic Compounds