title: Effects of Taishan Robinia pseudoacacia Polysaccharides on immune function in chickens.
abstract: To determine the immune function of Taishan Robinia pseudoacacia Polysaccharide (TRPPS) on chickens, 240 chickens were selected as experimental animals and treated with various doses of TRPPS by hypodermic injection before immunized NDV inactivated vaccine. The results indicated that any dose of TRPPS could significantly promote the development of the immune organs, increase the quantity of leukocyte and the ratio of lymphocyte, and improve the antibody titers against Newcastle disease. Meanwhile, it also increased the magnitude of SIgA in duodenum. However, the dose of 200 mg/ml showed to be the most effective. Therefore, in terms of improving immunologic function and production performance, TRPPS could be used as a vaccine immunopotentiator for immune responses.
authors.affiliation: Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Technology, Shandong Agricultural University, Shandong, Taian, 271018, PR China.
authors.forename: Man-fei
authors.initials: MF
authors.lastname: Liang
authors.forename: Guan-hua
authors.initials: GH
authors.lastname: Liu
authors.forename: Qing-you
authors.initials: QY
authors.lastname: Zhao
authors.forename: Shi-fa
authors.initials: SF
authors.lastname: Yang
authors.forename: Shi-xun
authors.initials: SX
authors.lastname: Zhong
authors.forename: Guo-lin
authors.initials: GL
authors.lastname: Cui
authors.forename: Xiao-hua
authors.initials: XH
authors.lastname: He
authors.forename: Xue
authors.initials: X
authors.lastname: Zhao
authors.forename: Fan-xia
authors.initials: FX
authors.lastname: Guo
authors.forename: Cun
authors.initials: C
authors.lastname: Wu
authors.forename: Rui-liang
authors.initials: RL
authors.lastname: Zhu
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage / Q000302:isolation & purification / Q000627:therapeutic use*; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002645:Chickens / Q000276:immunology*; D004195:Disease Models, Animal; D004386:Duodenum / Q000187:drug effects / Q000276:immunology; D056724:Immunity, Humoral / Q000187:drug effects; D018928:Immunity, Mucosal / Q000187:drug effects; D007071:Immunoglobulin A, Secretory / Q000276:immunology; D007958:Leukocyte Count; D009521:Newcastle Disease / Q000276:immunology / Q000517:prevention & control*; D009522:Newcastle disease virus / Q000276:immunology; D011134:Polysaccharides / Q000008:administration & dosage / Q000302:isolation & purification / Q000627:therapeutic use*; D011201:Poultry Diseases / Q000276:immunology / Q000517:prevention & control*; D031301:Robinia / Q000737:chemistry*; D015164:Vaccines, Inactivated; D014765:Viral Vaccines / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D000914:Antibodies, Viral; D007071:Immunoglobulin A, Secretory; D011134:Polysaccharides; D015164:Vaccines, Inactivated; D014765:Viral Vaccines