title: Traffic control at the "Gut-GALT crossroads".
abstract: In mice treated with antibiotics to deplete commensal microbiota, there is a significant overhaul of host cellular disposition and function with CX3CR1+ mononuclear phagocytic cells carrying pathogenic and non-pathogenic administered bacteria to the (messenteric lymph node) MLN, resulting in T cell stimulation and IgA production.
authors.affiliation: Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Suryasarathi
authors.initials: S
authors.lastname: Dasgupta
authors.forename: Dennis L
authors.initials: DL
authors.lastname: Kasper
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000073883:CX3C Chemokine Receptor 1; D004926:Escherichia coli / Q000276:immunology / Q000472:pathogenicity; D007070:Immunoglobulin A / Q000378:metabolism; D008198:Lymph Nodes / Q000166:cytology / Q000382:microbiology*; D008643:Mesentery; D054892:Metagenome; D051379:Mice; D018345:Mice, Knockout; D053594:Myeloid Differentiation Factor 88 / Q000172:deficiency / Q000235:genetics / Q000378:metabolism; D019707:Receptors, Chemokine / Q000235:genetics / Q000378:metabolism; D019779:Salmonella enterica / Q000276:immunology / Q000472:pathogenicity; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D000073883:CX3C Chemokine Receptor 1; C471885:Cx3cr1 protein, mouse; D007070:Immunoglobulin A; C507780:Myd88 protein, mouse; D053594:Myeloid Differentiation Factor 88; D019707:Receptors, Chemokine