title: Obesity and colorectal adenomatous polyps: a cross-sectional study in Korean adults.
abstract: OBJECTIVE
  This study aimed to examine the association between obesity and the risk of colorectal adenomatous polyps.
  
  
  METHODS
  The design of this study is a cross-sectional study. A total of 1,574 participants (818 males and 756 females), who had undergone colonoscopy for health examinations at the National Cancer Center hospital in South Korea from February to September 2009, were included in the analysis.
  
  
  RESULTS
  The prevalence of colorectal adenomatous polyps was 39.5% in males and 22.6% in females. In multiple logistic regression analysis, obesity (odds ratio [OR] = 1.69, 95% CI = 1.16-2.48) and abdominal obesity (OR = 1.59, 95% CI = 1.13-2.23) were significantly associated with an increased risk of colorectal adenomatous polyps in males, but not in females. In the subgroup analyses by age, obesity (OR = 2.27, 95% CI = 1.32-3.89), and abdominal obesity (OR = 1.76, 95% CI = 1.12-2.76) significantly increased a risk of colorectal adenomatous polyps in males aged <50 years, but not in males aged ≥50 years. However, interaction terms were not significant between obesity and gender (P = 0.397) and between obesity and age (P = 0.531) in the overall analyses.
  
  
  CONCLUSIONS
  Our findings should be explored in further research.
authors.affiliation: Center for Cancer Prevention and Detection, Hospital, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 410-769, Republic of Korea.
authors.forename: Ji Young
authors.initials: JY
authors.lastname: Lee
authors.forename: Sang Mi
authors.initials: SM
authors.lastname: Kwak
authors.forename: Seung-Kwon
authors.initials: SK
authors.lastname: Myung
authors.forename: Sun Ha
authors.initials: SH
authors.lastname: Jee
mesh_terms: D018256:Adenomatous Polyps / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D003430:Cross-Sectional Studies; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D056128:Obesity, Abdominal / Q000150:complications; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D012737:Sex Factors; D055105:Waist Circumference; D055815:Young Adult