title: [Endometriosis as a risk factor for ovarian cancer].
abstract: A history of endometriosis is a risk factor for some subtypes of epithelial ovarian cancer. Endometriosis is associated with increased risk of ovarian clear cell, serous low-grade endometrioid cancer, but it is unclear what the role of endometriosis is in the development of other histopathological subtypes of ovarian cancer, such as high-grade serous borderline tumors subtypes or borderline serous and mucinous cancers. An understanding of the mechanisms leading to malignant transformation of endometriosis will be needed to identify subgroups of women at increased risk of ovarian cancer. This is important because of their high prevalence and cause of infertility in Mexico and the world. All factors must be considered during the decision-making process for the treatment of endometriosis, including the rare malignant transformation.
authors.affiliation: Dirección de Investigación, Hospital Juárez de México, Secretaría de Salud, DF, Mexico. vvargashernandez@yahoo.com.mx
authors.forename: Víctor Manuel
authors.initials: VM
authors.lastname: Vargas-Hernández
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000453:epidemiology; D002288:Adenocarcinoma, Mucinous / Q000453:epidemiology; D018269:Carcinoma, Endometrioid / Q000453:epidemiology; D015897:Comorbidity; D018284:Cystadenocarcinoma, Serous / Q000453:epidemiology / Q000473:pathology; D004715:Endometriosis / Q000453:epidemiology*; D005260:Female; D052138:Genes, Neoplasm; D020022:Genetic Predisposition to Disease; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology; D008800:Mexico / Q000453:epidemiology; D009154:Mutation; D060787:Neoplasm Grading; D016017:Odds Ratio; D010051:Ovarian Neoplasms / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology; D015995:Prevalence; D012307:Risk Factors; D013997:Time Factors
keywords: endometriosis; infertility; ovarian cancer