title: Actinidia DRM1--an intrinsically disordered protein whose mRNA expression is inversely correlated with spring budbreak in kiwifruit.
abstract: Intrinsically disordered proteins (IDPs) are a relatively recently defined class of proteins which, under native conditions, lack a unique tertiary structure whilst maintaining essential biological functions. Functional classification of IDPs have implicated such proteins as being involved in various physiological processes including transcription and translation regulation, signal transduction and protein modification. Actinidia DRM1 (Ade DORMANCY ASSOCIATED GENE 1), represents a robust dormancy marker whose mRNA transcript expression exhibits a strong inverse correlation with the onset of growth following periods of physiological dormancy. Bioinformatic analyses suggest that DRM1 is plant specific and highly conserved at both the nucleotide and protein levels. It is predicted to be an intrinsically disordered protein with two distinct highly conserved domains. Several Actinidia DRM1 homologues, which align into two distinct Actinidia-specific families, Type I and Type II, have been identified. No candidates for the Arabidopsis DRM1-Homologue (AtDRM2) an additional family member, has been identified in Actinidia.
authors.affiliation: Genomics Research, The New Zealand Institute for Plant & Food Research Limited, Auckland, New Zealand. marion.wood@plantandfood.co.nz
authors.forename: Marion
authors.initials: M
authors.lastname: Wood
authors.forename: Georgina M
authors.initials: GM
authors.lastname: Rae
authors.forename: Rong-Mei
authors.initials: RM
authors.lastname: Wu
authors.forename: Eric F
authors.initials: EF
authors.lastname: Walton
authors.forename: Bin
authors.initials: B
authors.lastname: Xue
authors.forename: Roger P
authors.initials: RP
authors.lastname: Hellens
authors.forename: Vladimir N
authors.initials: VN
authors.lastname: Uversky
mesh_terms: D029042:Actinidia / Q000145:classification / Q000235:genetics* / Q000378:metabolism*; D000595:Amino Acid Sequence; D019295:Computational Biology / Q000379:methods; D005638:Fruit; D018506:Gene Expression Regulation, Plant; D056726:Genetic Association Studies; D008969:Molecular Sequence Data; D010802:Phylogeny; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D017433:Protein Structure, Secondary; D012333:RNA, Messenger; D012621:Seasons; D016415:Sequence Alignment
chemical_list: D010940:Plant Proteins; D012333:RNA, Messenger