title: [Bioflavonoids and their significance in angiology: focus on diosmin].
abstract: The article deals with historical information dedicated to the discovery of bioflavonoids and their effect on the human cardiovascular system, also considering the modern classification of phlebotrophic agents, followed by generalization and analysis of their mechanisms of action, as well as detailed discussion of different forms of diosmin. Summing up contains generalization of the Russian, European, and American guidelines on using phlebotrophic drugs for various forms and stages of chronic venous diseases.
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Bogachev
authors.forename: O V
authors.initials: OV
authors.lastname: Golovanova
authors.forename: A N
authors.initials: AN
authors.lastname: Kuznetsov
authors.forename: A O
authors.initials: AO
authors.lastname: Shekoian
mesh_terms: D001682:Biological Availability; D059350:Chronic Pain / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D004145:Diosmin / Q000008:administration & dosage / Q000493:pharmacokinetics; D005419:Flavonoids / Q000145:classification / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D008833:Microcirculation / Q000187:drug effects*; D020011:Protective Agents / Q000008:administration & dosage / Q000493:pharmacokinetics; D016896:Treatment Outcome; D014648:Varicose Veins / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D014680:Veins / Q000187:drug effects* / Q000503:physiopathology
chemical_list: D005419:Flavonoids; D020011:Protective Agents; D004145:Diosmin