title: A case of premature ovarian failure in a 33-year-old woman.
abstract: Objective. To assess aetiology of a POF in a 33-year-old woman and, if possible, plan a cure. Design. Case report. Setting. medical genetics diagnostic unit in a university hospital. Patient. A 33-year-old woman with premature ovarian failure (POF). Intervention(s). Genetic counseling, karyotyping, FISH study. Result(s). Turner-like diagnosis. Conclusion(s). Most cases of POF remain idiopathic. Turner syndrome can occur in very different phenotypes; cytogenetic and molecular profiling can provide a definitive diagnosis in cases with nonclassical phenotype.
authors.affiliation: Medical Genetics Unit, University Hospital "Policlinico Mater Domini", Magna Graecia University at Catanzaro, Viale Europa, Campus Salvatore Venuta, 88100 Catanzaro, Italy.
authors.forename: Emma
authors.initials: E
authors.lastname: Colao
authors.forename: Teresa
authors.initials: T
authors.lastname: Granata
authors.forename: Marco F M
authors.initials: MF
authors.lastname: Vismara
authors.forename: Francesco
authors.initials: F
authors.lastname: Bombardiere
authors.forename: Donatella
authors.initials: D
authors.lastname: Nocera
authors.forename: Elisa
authors.initials: E
authors.lastname: Luciano
authors.forename: Nicola
authors.initials: N
authors.lastname: Perrotti
authors.forename: Paola
authors.initials: P
authors.lastname: Malatesta