title: Perforating disseminated necrobiosis lipoidica diabeticorum.
abstract: Perforating necrobiosis lipoidica is a very rare clinical variant which consists of degeneration and transepidermal elimination of the collagen with few cases reported in the literature. In two-thirds of the patients it associates with diabetes, with no relation with the glucose control. We present a 42-year-old female patient with a 7-year history of diabetes on insulin therapy, referred to our clinic with a 3-year history of multiple asymptomatic firm plaques disseminated on the upper and lower extremities. The clinical and histological findings proved the diagnosis of perforating necrobiosis lipoidica.
authors.affiliation: Department of Dermatology and Venereology, Medical University Sofia, Sofia, Bulgaria.
authors.forename: Paula
authors.initials: P
authors.lastname: Lozanova
authors.forename: Lyubomir
authors.initials: L
authors.lastname: Dourmishev
authors.forename: Snejina
authors.initials: S
authors.lastname: Vassileva
authors.forename: Ljubka
authors.initials: L
authors.lastname: Miteva
authors.forename: Maria
authors.initials: M
authors.lastname: Balabanova