title: Phosphorylation and dephosphorylation of the RIG-I-like receptors: a safety latch on a fateful pathway.
abstract: Activation of antiviral responses by RNA sensors RIG-I and MDA5 must be stringently controlled. In this issue of Immunity, Wies et al. (2013) show that a requirement for activation-induced dephosphorylation of these proteins reinforces this restriction.
authors.affiliation: Department of Biological Chemistry, Weizmann Institute of Science, 76100 Rehovot, Israel. d.wallach@weizmann.ac.il
authors.forename: David
authors.initials: D
authors.lastname: Wallach
authors.forename: Andrew
authors.initials: A
authors.lastname: Kovalenko