title: Single institution experience with Tru-Cut renal mass biopsy for diagnosing Wilms tumor.
abstract: OBJECTIVE
  To evaluate the efficacy of needle biopsy for diagnosing Wilms tumor (WT) before chemotherapy.
  
  
  METHODS
  We reviewed our institutional experience with Tru-Cut biopsy of pediatric renal masses in patients who subsequently underwent nephrectomy. We compared biopsy pathology with nephrectomy specimens to determine if biopsy accurately predicted final pathology.
  
  
  RESULTS
  Seven children underwent Tru-Cut renal mass biopsy followed by surgical resection. In 4 patients, the final biopsy pathology was definitively read as WT and in 3 subjects, the pathology was read as WT versus hyperplastic nephrogenic rest. In all 7 patients, the nephrectomy pathology confirmed a diagnosis of WT. There were no complications after biopsy, and no patients have had local or regional recurrence.
  
  
  CONCLUSIONS
  In our experience, pre-therapy Tru-Cut biopsy safely provides an adequate specimen for pathologic review in diagnosing WT.
authors.affiliation: Division of Pediatric Urology, Children's Medical Center of Dallas, Dallas, Texas, USA. nicholas.cost@sbcglobal.net
authors.forename: Nicholas G
authors.initials: NG
authors.lastname: Cost
authors.forename: Candace F
authors.initials: CF
authors.lastname: Granberg
authors.forename: Bruce J
authors.initials: BJ
authors.lastname: Schlomer
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Wickiser
authors.forename: Patricio C
authors.initials: PC
authors.lastname: Gargollo
authors.forename: Linda A
authors.initials: LA
authors.lastname: Baker
authors.forename: Dinesh
authors.initials: D
authors.lastname: Rakheja
mesh_terms: D001707:Biopsy, Needle / Q000295:instrumentation*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D011237:Predictive Value of Tests; D009396:Wilms Tumor / Q000473:pathology* / Q000601:surgery