title: A new pyrazoline-based fluorescent probe for Cu2+ in live cells.
abstract: A new pyrazoline-based probe was synthesized and the structure was determined by using X-ray diffraction analysis. The probe responds to Cu(2+) in aqueous medium in "turn-off" fluorescent manner with selectivity and sensitivity. Furthermore, the probe could be used for real-time tracking of Cu(2+) in Hela cells.
authors.affiliation: Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan, 250100, People's Republic of China.
authors.forename: Meng-Meng
authors.initials: MM
authors.lastname: Li
authors.forename: Shu-Ya
authors.initials: SY
authors.lastname: Huang
authors.forename: Hui
authors.initials: H
authors.lastname: Ye
authors.forename: Fei
authors.initials: F
authors.lastname: Ge
authors.forename: Jun-Ying
authors.initials: JY
authors.lastname: Miao
authors.forename: Bao-Xiang
authors.initials: BX
authors.lastname: Zhao
mesh_terms: D000042:Absorption; D002470:Cell Survival; D003300:Copper / Q000032:analysis* / Q000737:chemistry* / Q000378:metabolism; D015195:Drug Design; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D042541:Intracellular Space / Q000378:metabolism; D007700:Kinetics; D057230:Limit of Detection; D016014:Linear Models; D057054:Molecular Imaging; D011720:Pyrazoles / Q000138:chemical synthesis / Q000737:chemistry*; D014867:Water / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D011720:Pyrazoles; D014867:Water; D003300:Copper