title: Lipid goal attainment and prescription behavior in asian patients with acute coronary syndromes: experience from a tertiary hospital.
abstract: Lipid goal attainment studies in Asian patients with acute coronary syndrome (ACS) are limited. The objectives of this study were to determine low-density lipoprotein cholesterol (LDL-C) goal attainment rate at 4 months, and to examine prescription behavior influencing lipid goal attainment in Asian patients with ACS. A retrospective analysis of 267 patients with ACS was performed. The mean follow-up duration was 41.2±10.7 months. LDL-C goal attainment rate was highest at 4 months (36.7%) but declined progressively throughout follow-up. More than 85% of patients were discharged with equipotent statin dose of 2 (equivalent to simvastatin 20 mg) or less. In patients who did not attain LDL-C goals, the statin dose remained low throughout follow-up because of a lack in responsive dose titration. Aggressive lipid-lowering therapy should be initiated early to improve goal attainment in these high-risk patients.
authors.affiliation: Department of Cardiology, National Heart Center Singapore, Singapore.
authors.forename: Calvin W
authors.initials: CW
authors.lastname: Chin
authors.forename: F
authors.initials: F
authors.lastname: Gao
authors.forename: Tt
authors.initials: T
authors.lastname: Le
authors.forename: Rs
authors.initials: R
authors.lastname: Tan
keywords: HMG Co-A reductase inhibitors; coronary artery disease; lipid goal attainment; secondary prevention