title: Primary intracranial germ-cell tumors in adults: a practical review.
abstract: Primary intracranial germ-cell tumors are rare tumors primarily of adolescence, and literature on this disease in adults is scarce. The available evidence on intracranial germ-cell tumors is reviewed with a focus on adult patients whenever possible, and used to make suggestions for diagnosis and treatment. Diagnostic and treatment algorithms were developed to provide an evidence-based backbone to base treatment on in adult patients with a (suspected) primary intracranial germ-cell tumor.
authors.affiliation: Department of Neuro-Oncology, Daniel den Hoed Cancer Center, Erasmus University Medical Center, P O Box 5201, 3008 AE, Rotterdam, The Netherlands. j.bromberg@erasmusmc.nl
authors.forename: Jacoline E C
authors.initials: JE
authors.lastname: Bromberg
authors.forename: Brigitta G
authors.initials: BG
authors.lastname: Baumert
authors.forename: Filip
authors.initials: F
authors.lastname: de Vos
authors.forename: Johanna M M
authors.initials: JM
authors.lastname: Gijtenbeek
authors.forename: Erkan
authors.initials: E
authors.lastname: Kurt
authors.forename: Anneke M
authors.initials: AM
authors.lastname: Westermann
authors.forename: Pieter
authors.initials: P
authors.lastname: Wesseling
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis* / Q000628:therapy*