title: Rare case of post-cataract-surgery Prevotella endophthalmitis diagnosed by polymerase chain reaction DNA sequencing.
abstract: We report the presentation, diagnosis, and management of endophthalmitis caused by the opportunistic Prevotella species. The case was referred to us following uneventful phacoemulsification and intraocular lens implantation. Accurate identification of this rare cause of endophthalmitis was made using bacterial polymerase chain reaction DNA sequencing. Subsequent prompt modification of antibacterial therapy allowed resolution of signs and symptoms and significant visual recovery. To our knowledge, this is the first reported case of diagnosis and management of post-cataract-surgery endophthalmitis caused by the opportunistic Prevotella species.
authors.affiliation: University Hospitals Coventry and Warwickshire, Coventry, United Kingdom.
authors.forename: Kwesi N
authors.initials: KN
authors.lastname: Amissah-Arthur
authors.forename: Tahir A
authors.initials: TA
authors.lastname: Farooq
authors.forename: Navpreet
authors.initials: N
authors.lastname: Dhillon
authors.forename: Ian A
authors.initials: IA
authors.lastname: Cunliffe
authors.forename: Atul
authors.initials: A
authors.lastname: Bansal
mesh_terms: D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016866:Bacteroidaceae Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D004269:DNA, Bacterial / Q000032:analysis; D004359:Drug Therapy, Combination; D009877:Endophthalmitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D015818:Eye Infections, Bacterial / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D018918:Phacoemulsification; D016133:Polymerase Chain Reaction; D011183:Postoperative Complications; D018720:Prevotella / Q000235:genetics / Q000302:isolation & purification*; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D012336:RNA, Ribosomal, 16S