title: A prospective, open-ended, single-cohort clinical trial on early loaded Titanium-zirconia alloy implants in partially edentulous patients: up-to-24-month results.
abstract: OBJECTIVE
  To evaluate biologic and prosthetic outcomes of titanium-zirconia alloy implants supporting fixed prostheses.
  
  
  METHODS
  A total of 52 titanium-zirconia alloy implants were placed in 23 consecutive patients with partial edentulism. All implants were subjected to an early loading protocol by means of single-unit or up-to-four-unit fixed partial prostheses and observed between 7 and 24 months. The radiographic marginal bone loss and peri-implant soft tissue scores (Plaque Index, Bleeding Index, and Calculus Index) were recorded. In addition, prosthetic complications were recorded during the period of the study.
  
  
  RESULTS
  Early or late implant failures were not observed, resulting in 100% implant survival and success of the implants. No prosthetic complications were observed. The mean (standard deviation) of marginal bone loss for 52 implants was 0.315 mm (0.24 mm). There were no signs of excessive bone loss with or without swelling or suppuration of the peri-implant soft tissue, and the soft tissue scores indicated good soft tissue integration.
  
  
  CONCLUSIONS
  Titanium-zirconia alloy implants supporting fixed prostheses showed optimum radiographic, clinical, and prosthetic outcomes in an up-to-24-month assessment period.
authors.affiliation: Department of Prosthodontics, Faculty of Dentistry, Hacettepe University, Sihhiye, Ankara, Turkey. akcak@hacettepe.edu.tr
authors.forename: Kivanc
authors.initials: K
authors.lastname: Akca
authors.forename: Yeliz
authors.initials: Y
authors.lastname: Cavusoglu
authors.forename: Serdar
authors.initials: S
authors.lastname: Uysal
authors.forename: Murat Cavit
authors.initials: MC
authors.lastname: Cehreli
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016301:Alveolar Bone Loss; D003722:Dental Alloys; D003758:Dental Implantation, Endosseous / Q000379:methods*; D003774:Dental Plaque Index; D017267:Dental Prosthesis Design; D019094:Dental Prosthesis, Implant-Supported; D005260:Female; D005884:Gingival Hemorrhage; D006801:Humans; D007576:Jaw, Edentulous, Partially / Q000534:rehabilitation*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014025:Titanium; D055815:Young Adult; D015040:Zirconium
chemical_list: D003722:Dental Alloys; D015040:Zirconium; D014025:Titanium; C028541:zirconium oxide