title: Optoelectronic plethysmography as an alternative method for the diagnosis of unilateral diaphragmatic weakness.
abstract: BACKGROUND
  The objective was to determine whether optoelectronic plethysmography (OEP) can detect asymmetric ventilation related to unilateral or asymmetric diaphragmatic weakness, suggesting usefulness as a diagnostic tool.
  
  
  METHODS
  Thirteen patients with suspected asymmetric diaphragmatic weakness based on dyspnea and hemidiaphragm elevation on the chest radiograph were studied as well as three patients with maltase acid deficiency (a cause of symmetrical diaphragmatic weakness). The transdiaphragmatic pressure response to unilateral magnetic stimulation (lateral twitch transdiaphragmatic pressure [latPdiTw]) and the diaphragm compound muscle action potentials (CMAPs) elicited by transcutaneous electrical stimulation of each phrenic nerve as well as OEP were performed.
  
  
  RESULTS
  The CMAPs and latPdiTw showed unilateral or predominantly unilateral diaphragmatic weakness in nine of the 13 patients. By OEP, the affected side of the thorax and abdomen contributed &lt; 45% of the inspiratory capacity in each of these nine patients, whereas no asymmetry was noted in the other four patients or in the three patients with maltase acid deficiency. All patients preferred OEP over CMAP or latPdiTw.
  
  
  CONCLUSIONS
  OEP detected asymmetric ventilation in all patients diagnosed with unilateral diaphragm weakness and in no patients without this diagnosis. Thus, OEP is an effective noninvasive alternative that is preferred by the patients over CMAP response and latPdiTw.
authors.affiliation: Centre d'Innovations Technologiques, UMR 805, Hôpital Raymond Poincaré, AP-HP, 92380, Garches; Université de Versailles Saint-Quentin-en-Yvelines, EA 4497, 78180 Montigny-le-Bretonneux, Versailles.
authors.forename: Julien
authors.initials: J
authors.lastname: Boudarham
authors.affiliation: Centre d'Innovations Technologiques, UMR 805, Hôpital Raymond Poincaré, AP-HP, 92380, Garches; Université de Versailles Saint-Quentin-en-Yvelines, EA 4497, 78180 Montigny-le-Bretonneux, Versailles.
authors.forename: Didier
authors.initials: D
authors.lastname: Pradon
authors.affiliation: Centre d'Innovations Technologiques, UMR 805, Hôpital Raymond Poincaré, AP-HP, 92380, Garches; Université de Versailles Saint-Quentin-en-Yvelines, EA 4497, 78180 Montigny-le-Bretonneux, Versailles.
authors.forename: Hélène
authors.initials: H
authors.lastname: Prigent
authors.affiliation: Centre d'Innovations Technologiques, UMR 805, Hôpital Raymond Poincaré, AP-HP, 92380, Garches; Université de Versailles Saint-Quentin-en-Yvelines, EA 4497, 78180 Montigny-le-Bretonneux, Versailles.
authors.forename: Line
authors.initials: L
authors.lastname: Falaize
authors.affiliation: Centre d'Innovations Technologiques, UMR 805, Hôpital Raymond Poincaré, AP-HP, 92380, Garches; Université de Versailles Saint-Quentin-en-Yvelines, EA 4497, 78180 Montigny-le-Bretonneux, Versailles.
authors.forename: Marie-Christine
authors.initials: MC
authors.lastname: Durand
authors.affiliation: Centre d'Innovations Technologiques, UMR 805, Hôpital Raymond Poincaré, AP-HP, 92380, Garches; Université de Versailles Saint-Quentin-en-Yvelines, EA 4497, 78180 Montigny-le-Bretonneux, Versailles.
authors.forename: Henri
authors.initials: H
authors.lastname: Meric
authors.affiliation: Physiologie - Explorations Fonctionnelles, Hôpital Ambroise Paré, AP-HP, 92104, Boulogne; Université de Versailles Saint-Quentin-en-Yvelines, EA 4497, 78180 Montigny-le-Bretonneux, Versailles; Center Hospitalier Universitaire d'Amiens, Amiens.
authors.forename: Michel
authors.initials: M
authors.lastname: Petitjean
authors.affiliation: Centre d'Innovations Technologiques, UMR 805, Hôpital Raymond Poincaré, AP-HP, 92380, Garches; Université de Versailles Saint-Quentin-en-Yvelines, EA 4497, 78180 Montigny-le-Bretonneux, Versailles; INSERM U855, 94000 Créteil, France. Electronic address: f.lofaso@rpc.ap-hop-paris.fr.
authors.forename: Frédéric
authors.initials: F
authors.lastname: Lofaso
mesh_terms: D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D003964:Diaphragm / Q000294:innervation* / Q000503:physiopathology; D004558:Electric Stimulation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D018908:Muscle Weakness / Q000175:diagnosis*; D010991:Plethysmography / Q000379:methods*; D015203:Reproducibility of Results; D012119:Respiration; D012133:Respiratory Paralysis / Q000175:diagnosis*