title: Use of photodynamic therapy for treatment of actinic keratoses in organ transplant recipients.
abstract: Solid organ transplant recipients are predisposed to actinic keratoses (AK) and nonmelanoma skin cancers, owing to the lifelong immunosuppression required. Today, increasing numbers of organ transplants are being performed and organ transplant recipients (OTRs) are surviving much longer. Photodynamic therapy (PDT) is proving a highly effective treatment modality for AK amongst this susceptible group of patients. Following an overview of the pathogenesis of AK amongst OTRs, the authors review current safety and efficacy data and how this relates to the role of PDT for the treatment of AK in OTRs.
authors.affiliation: St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, UK.
authors.forename: Christina
authors.initials: C
authors.lastname: Wlodek
authors.forename: Faisal R
authors.initials: FR
authors.lastname: Ali
authors.forename: John T
authors.initials: JT
authors.lastname: Lear
mesh_terms: D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D055623:Keratosis, Actinic / Q000150:complications / Q000628:therapy*; D016377:Organ Transplantation; D010778:Photochemotherapy / Q000009:adverse effects; D017319:Photosensitizing Agents / Q000627:therapeutic use; D010936:Plant Extracts / Q000627:therapeutic use; D012307:Risk Factors; D012878:Skin Neoplasms / Q000150:complications / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D017319:Photosensitizing Agents; D010936:Plant Extracts