title: Diverse topologies in dynamic combinatorial libraries from tri- and mono-thiols in water: sensitivity to weak supramolecular interactions.
abstract: We describe here the use of disulfide exchange reactions to generate distinct supramolecular topologies within a dynamic combinatorial library (DCL) derived from tri- and mono-functionalised thiol components in water. This approach allows for the effective expansion of structural diversity within a DCL, and also provides a sensitive probe for weak supramolecular interactions.
authors.affiliation: University Chemical Laboratory, University of Cambridge, Lensfield Road, Cambridge, UK CB21EW. as2044@cam.ac.uk
authors.forename: Artur R
authors.initials: AR
authors.lastname: Stefankiewicz
authors.forename: Jeremy K M
authors.initials: JK
authors.lastname: Sanders