title: Vitamin D and obesity.
abstract: Obesity is a significant health problem world-wide, particularly in developed nations. Vitamin D deficiency is pandemic, and has been implicated in a wide variety of disease states. This paper seeks to examine the consistently reported relationship between obesity and low vitamin D concentrations, with reference to the possible underlying mechanisms. The possibility that vitamin D may assist in preventing or treating obesity is also examined, and recommendations for future research are made. There is a clear need for adequately-powered, prospective interventions which include baseline measurement of 25D concentrations and involve adequate doses of supplemental vitamin D. Until such studies have been reported, the role of vitamin D supplementation in obesity prevention remains uncertain.
authors.affiliation: Discipline of General Practice, School of Population Health, University of Adelaide, Adelaide, South Australia, SA 5005, Australia. simon.vanlint@adelaide.edu.au
authors.forename: Simon
authors.initials: S
authors.lastname: Vanlint
mesh_terms: D002118:Calcium / Q000378:metabolism; D006801:Humans; D009765:Obesity / Q000209:etiology* / Q000517:prevention & control; D014807:Vitamin D / Q000494:pharmacology*; D014808:Vitamin D Deficiency / Q000150:complications*
chemical_list: D014807:Vitamin D; D002118:Calcium