title: The cognitive consequences of stigma, social withdrawal, and depression in adults aging with HIV.
abstract: In addition to the immune system, HIV also affects the nervous system. Even with highly active antiretroviral therapy helping reduce the impact of HIV on the body and brain, approximately 50% of individuals with HIV experience cognitive problems. As people age with HIV, there is growing concern that they will be at increased risk of developing cognitive problems that may have an impact on their everyday functioning (e.g., medication adherence) and quality of life. Unfortunately, HIV-related stigma, social withdrawal, and depression, which are common to the HIV experience, can also have direct and indirect negative consequences on cognition. Research and practice implications concerning these relationships are posited.
authors.affiliation: Center for Nursing Research, School of Nursing, Edward R. Roybal Center for Translational Research in Aging and Mobility, University of Alabama at Birmingham, Birmingham, Alabama 35294-1210, USA. devance@uab.edu
authors.forename: David E
authors.initials: DE
authors.lastname: Vance
mesh_terms: D015526:AIDS Dementia Complex / Q000188:drug therapy / Q000451:nursing* / Q000503:physiopathology / Q000523:psychology*; D000328:Adult; D000368:Aged; D019380:Anti-HIV Agents / Q000627:therapeutic use; D001921:Brain / Q000187:drug effects / Q000503:physiopathology; D003072:Cognition Disorders / Q000451:nursing* / Q000503:physiopathology / Q000523:psychology*; D058245:Cognitive Reserve / Q000187:drug effects / Q000502:physiology; D003866:Depressive Disorder / Q000451:nursing* / Q000503:physiopathology / Q000523:psychology*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000451:nursing* / Q000503:physiopathology / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012934:Social Isolation; D057545:Social Stigma
chemical_list: D019380:Anti-HIV Agents