title: Validation of the measurement of intra-abdominal fat between ultrasound and CT scan in women with obesity and infertility.
abstract: OBJECTIVE
  To compare the means and changes over time of intra-abdominal fat (IAF) and subcutaneous abdominal fat (SAF) measured by abdominal ultrasound (US) and computerized tomography (CT).
  
  
  METHODS
  Prospective cohort study of 53 women with obesity and infertility undergoing a lifestyle program.
  
  
  RESULTS
  The Pearson's correlation between IAF measurement by US compared to CT was good at baseline, month 3 and 6 (all r ≥ 0.72). The correlation of SAF measurement by US compared to CT was reasonable at baseline (r = 0.54; 95%CI 0.30-0.78) and weak at month 3 and 6 (all r ≤ 0.39). The correlation between the changes in IAF over 3 and 6 months by US compared to CT was reasonable and significant respectively (all r > 0.48). US could not measure the changes of SAF over time. The Bland-Altman plot showed good agreement between US and CT for IAF measurements (-1.1 [95%CI -3.9-1.6] cm lower mean in US) at baseline. For changes of IAF over time, mean estimates were in agreement.
  
  
  CONCLUSIONS
  In women with obesity and infertility, measuring IAF by US is in good agreement with the CT scan methodology but the measurement of SAF by US is unreliable.
authors.affiliation: Department of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Department of Obstetrics and Gynaecology, Isala Clinics, Zwolle, The Netherlands.
authors.forename: Walter K H
authors.initials: WK
authors.lastname: Kuchenbecker
authors.forename: Henk
authors.initials: H
authors.lastname: Groen
authors.forename: Heleen
authors.initials: H
authors.lastname: Pel
authors.forename: Johanna H T
authors.initials: JH
authors.lastname: Bolster
authors.forename: Bruce H R
authors.initials: BH
authors.lastname: Wolffenbuttel
authors.forename: Jolande A
authors.initials: JA
authors.lastname: Land
authors.forename: Annemieke
authors.initials: A
authors.lastname: Hoek
authors.forename: Eva
authors.initials: E
authors.lastname: Corpeleijn
mesh_terms: D050154:Adiposity; D000328:Adult; D015992:Body Mass Index; D015331:Cohort Studies; D003131:Combined Modality Therapy; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000150:complications* / Q000628:therapy; D050152:Intra-Abdominal Fat / Q000000981:diagnostic imaging*; D008019:Life Style; D009765:Obesity / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D056128:Obesity, Abdominal / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy; D011446:Prospective Studies; D015203:Reproducibility of Results; D050507:Subcutaneous Fat, Abdominal / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D055105:Waist Circumference; D015431:Weight Loss