title: Ciprofloxacin DPI in non-cystic fibrosis bronchiectasis: a Phase II randomized study.
abstract: BACKGROUND
  In non-cystic fibrosis (CF) bronchiectasis, the chronic airways infection is a risk factor for frequent infectious exacerbations and for an overall poor disease prognosis. Its therapy with inhaled antibiotics might be useful alike in the case of the CF-related disease.
  
  
  METHODS
  Analysis and discussion of the results of a Phase II study evaluating the efficacy and safety of the inhaled ciprofloxacin-dry powder (C-DPI) formulation in patients with non-CF bronchiectasis.
  
  
  CONCLUSIONS
  On short-term basis C-DPI is able to reduce the sputum bacterial load in such patients but long-term studies are also needed to better characterize the clinical efficacy of this compound.
authors.affiliation: Department of Interdisciplinarity Nursing, University of Medicine and Pharmacy Grigore T Popa, 16 Universităţii Str, 700115 Iasi, Romania. sabinaantoniu@yahoo.com
authors.forename: Sabina
authors.initials: S
authors.lastname: Antoniu
authors.forename: Doina
authors.initials: D
authors.lastname: Azoicai