title: A Pd(II)-catalyzed asymmetric approach toward chiral [3.3.1]-bicyclic ketals using 2-hydroxyphenylboronic acid as a pro-bis(nucleophile).
abstract: Enantioselective Pd(II)-catalyzed construction of [3.3.1]-bicyclic ketals from 2-hydroxyphenylboronic acid and enone is reported, yielding enantioenriched [3.3.1]-bicyclic ketals in up to 97% yields and 98% ee.
authors.affiliation: Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology, 130 MeiLong Road, Shanghai 200237, PR China. feijunwang@ecust.edu.cn
authors.forename: Feijun
authors.initials: F
authors.lastname: Wang
authors.forename: Feng
authors.initials: F
authors.lastname: Chen
authors.forename: Mingliang
authors.initials: M
authors.lastname: Qu
authors.forename: Teng
authors.initials: T
authors.lastname: Li
authors.forename: Yunlong
authors.initials: Y
authors.lastname: Liu
authors.forename: Min
authors.initials: M
authors.lastname: Shi
mesh_terms: D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001897:Boronic Acids; D010165:Palladium