title: Anterior skull base oncocytoma.
abstract: Oncocytic neoplasms are tumors composed of oncocytes (ie, epithelial cells with a large cytoplasm that is rich in mitochondria). Most cases are benign and originate from the salivary glands. Although there have been a few reported cases of oncocytomas being found in the sinonasal tract, most if not all cases seem not to involve the anterior skull base. We report a rare case of oncocytoma involving the anterior skull base occurring in a 44-year-old male patient. Preoperative carotid angiography and selective embolization was performed. The patient underwent an expanded endoscopic endonasal anterior craniofacial resection, which allowed complete resection of the tumor, with a low morbidity. The pathological diagnosis was oncocytoma. At 36 months after the initial treatment, the patient is free of disease. Based on our literature search, this may be the first such reported case. A brief review of the available literature examining the known body of knowledge regarding these neoplasms is presented.
authors.affiliation: Department of Otorhinolaringology, Unit of Skull Base, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain. flopez_1981@yahoo.es
authors.forename: Fernando
authors.initials: F
authors.lastname: López
authors.forename: Blanca
authors.initials: B
authors.lastname: Vivanco
authors.forename: Carlos
authors.initials: C
authors.lastname: Suárez
authors.forename: José L
authors.initials: JL
authors.lastname: Llorente
mesh_terms: D018249:Adenoma, Oxyphilic / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D000328:Adult; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D004724:Endoscopy; D006801:Humans; D008297:Male; D019292:Skull Base Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*