title: A simple route to prepare monodisperse Au NP-decorated, dye-doped, superparamagnetic nanocomposites for optical, MR, and CT trimodal imaging.
abstract: Monodisperse and uniform AuNP-decorated, dye-doped, superparamagnetic nanocomposites (Fe3 O4 @dye-hybrid@Au) are fabricated by using a simple method in which the Au NP formation and their attachment onto the core surface via S-Au covalent bonds proceeds almost simultaneously in a one-pot synthesis. The as-synthesized nanocomposites can simultaneously enhance the contrast effects for MR, CT, and cellular-sensitive optical imaging.
authors.affiliation: Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China.
authors.forename: Wenjie
authors.initials: W
authors.lastname: Dong
authors.forename: Yongsheng
authors.initials: Y
authors.lastname: Li
authors.forename: Dechao
authors.initials: D
authors.lastname: Niu
authors.forename: Zhi
authors.initials: Z
authors.lastname: Ma
authors.forename: Xiaohang
authors.initials: X
authors.lastname: Liu
authors.forename: Jinlou
authors.initials: J
authors.lastname: Gu
authors.forename: Wenru
authors.initials: W
authors.lastname: Zhao
authors.forename: Yuanyi
authors.initials: Y
authors.lastname: Zheng
authors.forename: Jianlin
authors.initials: J
authors.lastname: Shi
mesh_terms: D000818:Animals; D004396:Coloring Agents / Q000737:chemistry; D003911:Dextrans / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D006801:Humans; D061986:MCF-7 Cells; D008279:Magnetic Resonance Imaging; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D051379:Mice; D053761:Nanocomposites / Q000737:chemistry / Q000648:ultrastructure; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D036103:Nanotechnology / Q000379:methods*; D061848:Optical Imaging; D012822:Silicon Dioxide / Q000737:chemistry; D013113:Spin Labels; D014057:Tomography, X-Ray Computed
chemical_list: D004396:Coloring Agents; D003911:Dextrans; D058185:Magnetite Nanoparticles; D013113:Spin Labels; D006046:Gold; D012822:Silicon Dioxide; C065507:ferumoxides
keywords: computed tomography; gold nanoparticles; magnetic resonance imaging; nanocomposites; superparamagnetics