title: Analysis of associated diseases in patients with acute critical lower limb ischemia.
abstract: BACKGROUND
  Acute critical lower limb ischemia refers to the state of severely impaired vitality of lower limbs due to acute occlusion of arterial blood vessel by a thrombus or emboli. Surgical revascularization in the first 6-12 hours after the onset of symptoms gives the best results. However, a high mortality rate and probability of limb loss make this problem more debatable, and can be related with associated diseases.
  
  
  METHODS
  This research included 95 patients who had been operated within the first 12 hours after the onset of symptoms of critical limb ischemia We collected the following data: age and sex of patients, etiology of limb ischemia, type of operation, associated diseases and outcome of treatment.
  
  
  CONCLUSIONS
  Most of the patients were 70 to 80 years old, both sexes being equally represented. There was significantly more arterial embolism (70%) than thrombosis on the prior arterial lesion. Most of the embolizations were treated with Fogarty balloon catheter embolectomy (98%); however, a great number ofarterial thrombosis demanded more complex "inflow" and "outflow" ensuring procedures such as thromboendarterectomy and bypass (33%). The performed surgical procedures showed no statistical differences when final outcome was analyzed. Amputation had to be performed in about 3% of the patients and all of them were diabetics. Mortality rate in this research was 10.5% and 7/10 with this outcome had severe form of chronic myocardiopathy and metabolic decompensation.
  
  
  CONCLUSIONS
  Acute critical lower limb ischemia should be treated surgically as soon as possible. Negative outcomes are associated with comorbidity and general condition of the patient.
authors.affiliation: Department for Vascular Surgery, Clinical Centre of Vojvodina, Novi Sad. drvladimirmanojlovic78@gmail.com
authors.forename: Vladimir
authors.initials: V
authors.lastname: Manojlović
authors.forename: Vladan
authors.initials: V
authors.lastname: Popović
authors.forename: Dragan
authors.initials: D
authors.lastname: Nikolić
authors.forename: Dorde
authors.initials: D
authors.lastname: Milosević
authors.forename: Janko
authors.initials: J
authors.lastname: Pasternak
authors.forename: Milos
authors.initials: M
authors.lastname: Kaćanski
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004617:Embolism / Q000150:complications*; D005260:Female; D006801:Humans; D007511:Ischemia / Q000209:etiology* / Q000601:surgery; D035002:Lower Extremity / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D013927:Thrombosis / Q000150:complications*