title: Endocrine-disrupting chemicals and male reproductive health.
abstract: Endocrine-disrupting chemicals are substances present in the environment that can interfere with normal hormonal balance and thus exert potentially adverse health effects on the human organism. Male reproductive system development and function may be susceptible to the effects of such environmental toxicants. Bisphenol A, phthalates and alkylphenols are important components of multiple products and are thus ubiquitously present in the environment. It has been demonstrated under laboratory conditions that they can exert detrimental effects on the male reproductive system. However, human exposure data are scarce and do not uniformly support toxicity of these substances at environmental concentrations. Despite substantial research efforts, the final answer to the problem of endocrine-disrupting chemicals is not yet in sight.
authors.affiliation: Department of Reproductive Medicine and Gynaecologic Endocrinology, University Medical Centre Maribor, Ljubljanska 5, 2000 Maribor, Slovenia. knez.jure@gmail.com
authors.forename: Jure
authors.initials: J
authors.lastname: Knez
mesh_terms: D000818:Animals; D001559:Benzhydryl Compounds / Q000009:adverse effects; D052244:Endocrine Disruptors / Q000009:adverse effects*; D006801:Humans; D007248:Infertility, Male / Q000453:epidemiology* / Q000503:physiopathology*; D008297:Male; D023421:Models, Animal; D010636:Phenols / Q000009:adverse effects; D010795:Phthalic Acids / Q000009:adverse effects; D015995:Prevalence; D060728:Reproductive Health; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D052244:Endocrine Disruptors; D010636:Phenols; D010795:Phthalic Acids; C006780:bisphenol A; D000098826:Bisphenol A Compounds