title: [Clinical profile of patients with very high hypertriglyceridemia from the Registry of Hypertriglyceridemia of the Spanish Atherosclerosis Society].
abstract: OBJECTIVE
  To describe clinical and epidemiological characteristics of patients with very high hypertriglyceridemia (HTG) who were attended in lipid units of the Spanish Society of Atherosclerosis (SEA).
  
  
  METHODS
  Patients of the HTG Registry of SEA with at least one triglyceride concentration greater than 1,000mg/dL (n=298, HTG severe group) and those whose baseline triglycerides were between 200 and 246mg/dL (HTG control group, n=272) were included.
  
  
  RESULTS
  Patients with very high triglyceride levels were younger (46.9±11.5 years vs 52.7±13 years; p<0.0001), with a larger waist circumference (100.5±10.6cm vs 98.5±11.1cm; p=0.0426), higher alcohol intake (170.7±179.1g/wk vs 118.8±106.4g/wk; p=0,0473), active smoking status (45.6% vs 26.8%; p<0.0001) and a higher frequency of pancreatitis (10.2% vs 3%; p=0.0006) than HTG control group. There was a higher percentage of patients with atherogenic dietary pattern in severe HTG group compared with the control group (138 [46.3%] vs. 94 [34.5%]; p=0,001). The multivariate analysis showed that factors associated with a triglyceride concentration greater than 1,000mg/dl were age, male sex, weight, waist circumference, alcohol, physical inactivity in non-business hours and the presence of diabetes mellitus.
  
  
  CONCLUSIONS
  Patients with very high HTG were usually men in the fourth decade of life, with abdominal obesity, smoking and alcohol consumption. In 60% of cases the HTG was primary, and pancreatitis the most frequently complication.
authors.affiliation: Unitat de Lípids i Risc Vascular, Hospital del Mar, Universitat Autònoma de Barcelona, Barcelona, España.
authors.forename: Angels
authors.initials: A
authors.lastname: Pedragosa
authors.forename: Jordi
authors.initials: J
authors.lastname: Merino
authors.forename: José L
authors.initials: JL
authors.lastname: Aranda
authors.forename: Jesús
authors.initials: J
authors.lastname: Galiana
authors.forename: Diego
authors.initials: D
authors.lastname: Godoy
authors.forename: Josefa M
authors.initials: JM
authors.lastname: Panisello
authors.forename: Juan F
authors.initials: JF
authors.lastname: Ascaso
authors.forename: Fernando
authors.initials: F
authors.lastname: Civeira
authors.forename: Luis
authors.initials: L
authors.lastname: Masana
authors.forename: Juan
authors.initials: J
authors.lastname: Pedro-Botet
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000428:Alcohol Drinking / Q000453:epidemiology*; D004036:Diet, Atherogenic / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D015228:Hypertriglyceridemia / Q000150:complications / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D056128:Obesity, Abdominal / Q000453:epidemiology*; D010195:Pancreatitis / Q000453:epidemiology / Q000209:etiology; D012042:Registries; D012720:Severity of Illness Index; D012737:Sex Factors; D012907:Smoking / Q000453:epidemiology*; D013030:Spain / Q000453:epidemiology; D055105:Waist Circumference