title: Infection rate following total joint arthroplasty in the HIV population.
abstract: The purpose of this study is to review a large series of HIV-infected patients who underwent total joint arthroplasty and identify potential risk-factors for infection. Sixty-nine HIV-infected arthroplasty cases were analyzed with 138 matched controls. Deep infection rate following total hip or knee arthroplasty was 4.4% (3 of 69) among HIV cases compared to 0.72% (1 of 138) among controls, yielding a non-significant 6.22 times increased odds of infection (95% CI 0.64-61.0, P=0.11). Kaplan-Meier survival curves for infection free survival and revision free survival revealed non-significantly decreased survival in HIV cases compared to controls (P=0.06 and P=0.09). Our results suggest that the rate of early joint infection following primary total joint arthroplasty in the HIV-infected population is lower than reported in a number of previously published studies.
authors.affiliation: Department of Orthopaedic Surgery, New York University Hospital for Joint Diseases, New York, New York, USA.
authors.forename: Brian M
authors.initials: BM
authors.lastname: Capogna
authors.forename: Andrew
authors.initials: A
authors.lastname: Lovy
authors.forename: Yossef
authors.initials: Y
authors.lastname: Blum
authors.forename: Sun Jin
authors.initials: SJ
authors.lastname: Kim
authors.forename: Uriel R
authors.initials: UR
authors.lastname: Felsen
authors.forename: David S
authors.initials: DS
authors.lastname: Geller
mesh_terms: D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D019645:Arthroplasty, Replacement, Knee; D016022:Case-Control Studies; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D015994:Incidence; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D012189:Retrospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000209:etiology
keywords: arthroplasty; hip; human immunodeficiency virus (HIV); infection; knee