title: One-step synthesis of isocoumarins and 3-benzylidenephthalides via ligandless Pd-catalyzed oxidative coupling of benzoic acids and vinylarenes.
abstract: A straightforward synthetic method for the preparation of isocoumarins and 3-benzylidenephthalides via C-H olefination and oxidative coupling of readily available benzoic acids and vinylarenes was developed. The directing effect of the substituents on the benzoic acid allows for the synthesis of both types of lactone in pure form.
authors.affiliation: Department of Chemistry, National Changhua University of Education, Changhua 50058, Taiwan, R.O.C.
authors.forename: Debkumar
authors.initials: D
authors.lastname: Nandi
authors.forename: Debalina
authors.initials: D
authors.lastname: Ghosh
authors.forename: Shih-Ji
authors.initials: SJ
authors.lastname: Chen
authors.forename: Bing-Chiuan
authors.initials: BC
authors.lastname: Kuo
authors.forename: Nancy M
authors.initials: NM
authors.lastname: Wang
authors.forename: Hon Man
authors.initials: HM
authors.lastname: Lee
mesh_terms: D001565:Benzoates / Q000737:chemistry*; D001597:Benzylidene Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D049934:Isocoumarins / Q000138:chemical synthesis* / Q000737:chemistry; D008024:Ligands; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D014753:Vinyl Compounds / Q000737:chemistry*
chemical_list: D001565:Benzoates; D001597:Benzylidene Compounds; D049934:Isocoumarins; D008024:Ligands; D009942:Organometallic Compounds; D014753:Vinyl Compounds; C011404:benzylidenephthalide; D010165:Palladium