title: Heart surgery in patients on chronic dialysis.
abstract: BACKGROUND
  Patients on dialysis for end-stage renal failure are subjected to cardiac surgery with increasing frequency. End-stage renal failure is known to be an important risk factor for complications of cardiac operations performed with cardiopulmonary bypass. The aim of this study was to determine the impact of preoperative clinical status and operative variables on perioperative morbidity and mortality in hemodialysis-dependent patients subjected to a cardiac surgery.
  
  
  METHODS
  The following operative variables were examined: urgency, type and duration of surgery and duration of extracorporeal circulation. The study is a retrospective analysis of consecutive patients with end-stage renal failure dependent on maintenance hemodialysis who underwent cardiac surgery during four years.
  
  
  RESULTS
  The study included 46 patients. Operations performed included isolated coronary artery bypass grafting (CABG, n = 24), valve surgery alone (n = 6), and combined valve surgery or coronary artery bypass grafting and valve surgery (n = 16). The perioperative mortality rate was 13% with four fatal outcomes in patients who had undergone combined cardiac surgery. We found age > 70 years, preoperative New York Heart Association class IV, preoperative anemia, combined surgery and emergent surgery to be associated with a higher relative risk for perioperative death.
  
  
  CONCLUSIONS
  Patients on dialysis have an increased morbidity and mortality following cardiac surgery; however, we believe that end-stage renal failure should not be regarded as a contraindication to cardiac surgery or cardiopulmonary bypass.
authors.affiliation: Clinic for Anesthesiology and Intensive Care, Cardiovascular Institute Dedinje Belgrade, Serbia. dunic@yubc.net
authors.forename: Dragana
authors.initials: D
authors.lastname: Unić Stojanović
authors.forename: Miroslav
authors.initials: M
authors.lastname: Milicić
authors.forename: Petar
authors.initials: P
authors.lastname: Vuković
authors.forename: Srdan
authors.initials: S
authors.lastname: Babić
authors.forename: Miomir
authors.initials: M
authors.lastname: Jović
mesh_terms: D000328:Adult; D000368:Aged; D006348:Cardiac Surgical Procedures / Q000401:mortality; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D006435:Renal Dialysis; D012307:Risk Factors