title: Prognostic value of stress hyperglycemia for in-hospital outcome in acute coronary artery disease.
abstract: BACKGROUND
  In acute coronary syndrome (ACS), admission hyperglycemia is associated with adverse cardiovascular events in diabetic and nondiabetic patients.
  
  
  OBJECTIVE
  To assess the prognostic value of stress hyperglycemia for the in-hospital outcome of patients admitted due to ACS.
  
  
  METHODS
  This study included 152 patients admitted to the chest pain unit of a tertiary hospital diagnosed with ACS, who had admission blood glucose data, from September 2005 to February 2010. Group I comprised patients with stress hyperglycemia, defined as admission blood glucose concentration > 126 mg/dL for nondiabetic individuals and admission blood glucose concentration > 200 mg/dL for diabetic individuals. Group II was formed by patients with admission blood glucose concentration lower than those established. The association of hyperglycemia and in-hospital outcome was assessed.
  
  
  RESULTS
  Stress hyperglycemia associated with in-hospital complications, age increase and female sex. On multivariate analysis, only female sex (OR = 2.04; 95% CI: 1.03 - 4.06; p = 0.007) and in-hospital complications (OR = 3.65; 95% CI: 1.62 - 8.19; p = 0.002) associated independently with admission hyperglycemia.
  
  
  CONCLUSIONS
  Stress hyperglycemia is an independent predictive factor for in-hospital complications after ACS in diabetic and nondiabetic patients. The results highlight the need to assess admission blood glucose concentration in all patients admitted due to ACS, including nondiabetic ones, aiming at identifying those at higher risk for complications.
authors.affiliation: Departamento de Medicina, Universidade Federal de Sergipe, São Cristovão, SE, Brasil.
authors.forename: Carlos Passos
authors.initials: CP
authors.lastname: Pinheiro
authors.forename: Marcos Danillo Peixoto
authors.initials: MD
authors.lastname: Oliveira
authors.forename: Gustavo Baptista de Almeida
authors.initials: GB
authors.lastname: Faro
authors.forename: Esdras Correa
authors.initials: EC
authors.lastname: Silva
authors.forename: Eduardo Augusto Andrade da
authors.initials: EA
authors.lastname: Rocha
authors.forename: José Augusto Soares
authors.initials: JA
authors.lastname: Barreto-Filho
authors.forename: Joselina Luzia Menezes
authors.initials: JL
authors.lastname: Oliveira
authors.forename: Antônio Carlos Sobral
authors.initials: AC
authors.lastname: Sousa
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000150:complications; D000367:Age Factors; D000368:Aged; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis*; D048909:Diabetes Complications / Q000097:blood; D003920:Diabetes Mellitus / Q000097:blood*; D005260:Female; D006760:Hospitalization; D006801:Humans; D006943:Hyperglycemia / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012016:Reference Values; D012307:Risk Factors; D012737:Sex Factors
chemical_list: D015415:Biomarkers; D001786:Blood Glucose