title: Management of hyperparathyroidism (PHP) in MEN2 syndromes in Europe.
abstract: Hyperparathyroidism occurs in 20-30% of MEN2A syndrome patients. It is usually associated with mild disease and is frequently asymptomatic, especially in younger age. There is genotype/phenotype association and PHP is usually associated with codon 634 mutations; however association with more "rare" mutations has also been reported. The pathology of the parathyroid glands includes hyperplasia, adenoma or a combination of the two. The optimal surgical management of this entity has not been defined yet.
authors.affiliation: Endocrine Unit, Evgenidion Hospital and Dept Medical Therapeutics, Alexandra Hospital, Athens University School of Medicine, 11528 Athens, Greece. mani@otenet.gr.
authors.forename: Maria
authors.initials: M
authors.lastname: Alevizaki