title: Electrophoretic finding of bisalbuminemia.
abstract: BACKGROUND
  Bisalbuminemia or alloalbuminemia is a rare inherited or acquired condition characterized by the presence of two albumin fractions during electrophoretical separation of serum proteins.
  
  
  METHODS
  Bisalbuminemia was incidentally detected by agarose gel electrophoresis (AGE) during standard laboratory investigation of a 36-year old female patient, referred to our laboratory with the diagnosis of immune thrombocytopenia.
  
  
  RESULTS
  The electrophoregram showed dysproteinemia with the presence of two distinct albumin bands. This initiated testing of other family members - mother, father, and son of the patient.
  
  
  CONCLUSIONS
  We report a case of inherited bisalbuminemia in a Bulgarian family with two affected members of four investigated. This is the first report of inherited bisalbuminemia in the Plovdiv region and could be of great interest to laboratory practitioners and clinicians providing some new data on the protein evolution and the clinical approach.
authors.affiliation: Centre of Clinical Laboratory, University Hospital "St. George" Plovdiv, Bulgaria.
authors.forename: V
authors.initials: V
authors.lastname: Markova
authors.forename: I
authors.initials: I
authors.lastname: Nenova
authors.forename: T
authors.initials: T
authors.lastname: Deneva
authors.forename: E
authors.initials: E
authors.lastname: Beleva
authors.forename: J
authors.initials: J
authors.lastname: Grudeva-Popova
mesh_terms: D000328:Adult; D001796:Blood Protein Disorders / Q000175:diagnosis*; D004587:Electrophoresis, Agar Gel / Q000379:methods*; D005260:Female; D006801:Humans; D012709:Serum Albumin / Q000378:metabolism*
chemical_list: D012709:Serum Albumin