title: [Computer-assisted sperm analysis for assessing sperm mobility parameters in in vitro fertilization].
abstract: OBJECTIVE
  To evaluate the association of sperm mobility parameters assessed by computer-assisted sperm analysis (CASA) with the rates of normal fertilization, oocyte cleavage and excellent embryos in in vitro fertilization (IVF) cycles.
  
  
  METHODS
  A total of 288 infertile women undergoing IVF cycles patients were divided into two groups according to the normal fertilization rate (≥50% and <50%), cleavage rate (≥90% and <90%), or excellent embryo rates (≥50% and <50%). The means of the sperm motility parameters analyzed by CASA twice before oocyte retrieval were recorded and analyzed using t-test in relation to the rates of normal fertilization, cleavage and excellent embryos in IVF cycles.
  
  
  RESULTS
  The mean curvilinear velocity (VCL), average path velocity (VAP), and amplitude of lateral head displacement (ALH) were significantly higher in women with a normal fertilization rate of ≥50% than in those with a normal fertilization rate of <50% (P<0.05). Women with an oocyte cleavage rate of ≥90% had significantly higher VCL and VAP than those with a cleavage rate of <90% (P<0.05). The VCL, straight line velocity (VSL), VAP, linearity, straightness, wobble coefficient, ALH, or beat-cross frequency showed no significant differences between women with excellent embryo rates of ≥50% and <50% (P>0.05).
  
  
  CONCLUSIONS
  The sperm motility parameters assessed using CASA are associated with normal fertilization and oocyte cleavage rates but not with excellent embryo rate in IVF cycles.
authors.affiliation: Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. yuanpingqing2008@ yahoo.com.cn
authors.forename: Pingqing
authors.initials: P
authors.lastname: Yuan
authors.forename: Zhehuan
authors.initials: Z
authors.lastname: Zhang
authors.forename: Chen
authors.initials: C
authors.lastname: Luo
authors.forename: Song
authors.initials: S
authors.lastname: Quan
authors.forename: Qingjun
authors.initials: Q
authors.lastname: Chu
authors.forename: Shanchao
authors.initials: S
authors.lastname: Zhao
mesh_terms: D000328:Adult; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D055101:Semen Analysis; D013081:Sperm Motility; D013813:Therapy, Computer-Assisted