title: Recyclable copper catalyzed nitrogenation of biphenyl halides: a direct approach to carbazoles.
abstract: A novel A21-CuI catalyzed direct nitrogenation of biphenyl halides for the direct synthesis of carbazoles via a direct C-H amination process has been developed. A recyclable and inexpensive Cu-catalyst was successfully employed in N-heterocyclic compound synthesis via tandem azidation and C-H amination, which makes this protocol very practical and easy to handle.
authors.affiliation: State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Road 38, Beijing 100191, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Ou
authors.forename: Ning
authors.initials: N
authors.lastname: Jiao
mesh_terms: D000586:Amination; D001713:Biphenyl Compounds / Q000737:chemistry*; D002227:Carbazoles / Q000138:chemical synthesis / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D006219:Halogens / Q000737:chemistry; D006859:Hydrogen / Q000737:chemistry; D013696:Temperature
chemical_list: D001713:Biphenyl Compounds; D002227:Carbazoles; D002244:Carbon; D003300:Copper; D006219:Halogens; D006859:Hydrogen; C010574:biphenyl