title: The strength-interval curve in cardiac tissue.
abstract: The bidomain model describes the electrical properties of cardiac tissue and is often used to simulate the response of the heart to an electric shock. The strength-interval curve summarizes how refractory tissue is excited. This paper analyzes calculations of the strength-interval curve when a stimulus is applied through a unipolar electrode. In particular, the bidomain model is used to clarify why the cathodal and anodal strength-interval curves are different, and what the mechanism of the "dip" in the anodal strength-interval curve is.
authors.affiliation: Department of Physics, Oakland University, Rochester, MI 48309, USA.
authors.forename: Sunil M
authors.initials: SM
authors.lastname: Kandel
authors.forename: Bradley J
authors.initials: BJ
authors.lastname: Roth
mesh_terms: D002304:Cardiac Pacing, Artificial; D019295:Computational Biology / Q000379:methods; D003198:Computer Simulation; D004554:Electric Countershock; D004558:Electric Stimulation; D006321:Heart / Q000502:physiology*; D006329:Heart Conduction System / Q000502:physiology; D006801:Humans; D008955:Models, Cardiovascular; D009206:Myocardium / Q000473:pathology*