title: Stem cell transplantation in primary myelofibrosis of childhood.
abstract: Fewer than 40 cases of primary myelofibrosis have been reported in children; hematopoietic stem cell transplantation is the only available curative therapy for this disease. Here, we describe the case of a female infant diagnosed with primary myelofibrosis at the age of 6 months; she underwent successful matched unrelated bone marrow transplantation with complete resolution of disease. We discuss some unique characteristics of primary myelofibrosis in children and review outcome data for children with this disease.
authors.affiliation: Department of Pediatrics, Division of Hematology-Oncology, Mattel Children's Hospital at UCLA, Los Angeles, CA, USA.
authors.forename: Bryan
authors.initials: B
authors.lastname: Mitton
authors.forename: Satiro
authors.initials: S
authors.lastname: de Oliveira
authors.forename: Sheeja T
authors.initials: ST
authors.lastname: Pullarkat
authors.forename: Theodore B
authors.initials: TB
authors.lastname: Moore
mesh_terms: D016026:Bone Marrow Transplantation; D005260:Female; D006801:Humans; D007223:Infant; D055728:Primary Myelofibrosis / Q000175:diagnosis / Q000628:therapy*; D016896:Treatment Outcome