title: [Rhino-orbito-cerebral mucormycosis, surgical treatment, state of the art].
abstract: Rhino-orbito-cerebral mucormycoses constitute a severe fungal infection. These infections mostly arise in immunosuppressed patients. The surgery aiming at resecting necrosed hurts showed its interest in term of survival for lung and cutaneous mucormycosis. However, treatment of rhino-orbito-cerebral location of mucormycosis is not well defined. Transnasal endoscopic surgery allows local control of the disease, better post-operative outcomes than transfacial approaches and less sequelae. However, transfacial approaches are sometimes necessary to allow cutaneous resection or exenteration, the indications of which still remain controversial. The retrospective study of 22 patients with mucormycosis allowed to show that radical surgical treatment allowed local control of the disease with an improved survival. Further prospective studies (PHRC MICCA, current) are required to standardize the management of this rare but potentially lethal pathology.
authors.affiliation: Service d'otorhinolaryngologie et de chirurgie cervico-faciale, Hôpital Lariboisière, Paris, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Vironneau
authors.forename: Benjamin
authors.initials: B
authors.lastname: Verillaud
authors.forename: Hugo
authors.initials: H
authors.lastname: Tran
authors.forename: Khaled
authors.initials: K
authors.lastname: Altabaa
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Blancal
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Sauvaget
authors.forename: Philippe
authors.initials: P
authors.lastname: Herman
authors.forename: Romain
authors.initials: R
authors.lastname: Kania
mesh_terms: D001927:Brain Diseases / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D016867:Immunocompromised Host; D009091:Mucormycosis / Q000503:physiopathology / Q000601:surgery*; D009668:Nose Diseases / Q000382:microbiology* / Q000601:surgery; D009916:Orbital Diseases / Q000382:microbiology* / Q000601:surgery; D012189:Retrospective Studies; D012220:Rhinitis