title: On the determination of a detector response enhancement factor for flow modulated comprehensive two-dimensional gas chromatography.
abstract: Comparison of conventional one-dimensional gas chromatography (1D-GC) and comprehensive two-dimensional gas chromatography (GC×GC) shows that the detector signal in GC×GC is significantly enhanced. The value of this enhancement depends on the operating parameters, such as the modulation time and the non-modulated ((1)D column) and corresponding modulated ((2)D column) peak widths. Determination of the enhance factors in flow modulated GC×GC for separation of hydrocarbon samples using flame ionization detection (FM GC×GC-FID) was studied. A term named detector response enhance factor (DREF) has been designed to express the value of the signal enhancement. Two methods were used to calculate DREF: (i) employing (2)D peak height, and (ii) using a theoretical approach. Comparison of FM GC×GC-FID and 1D-GC-FID method illustrates that the DREF increases from 10 to 33 times, in 1-6s modulation time intervals.
authors.affiliation: Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, STU, Bratislava, Slovakia. jan.krupcik@stuba.sk
authors.forename: Ján
authors.initials: J
authors.lastname: Krupčík
authors.forename: Pavel
authors.initials: P
authors.lastname: Májek
authors.forename: Roman
authors.initials: R
authors.lastname: Gorovenko
authors.forename: Ivan
authors.initials: I
authors.lastname: Špánik
authors.forename: Pat
authors.initials: P
authors.lastname: Sandra
authors.forename: Daniel W
authors.initials: DW
authors.lastname: Armstrong
mesh_terms: D000473:Alkanes / Q000737:chemistry; D002849:Chromatography, Gas / Q000379:methods*; D005410:Flame Ionization; D005742:Gasoline / Q000032:analysis; D012815:Signal Processing, Computer-Assisted
chemical_list: D000473:Alkanes; D005742:Gasoline; C022884:undecane