title: Fluorescent water-soluble perylenediimide-cored cationic dendrimers: synthesis, optical properties, and cell uptake.
abstract: Different generations of perylenediimide-cored dendrimers with peripheral amine groups were synthesized. All these water-soluble dendrimers could rapidly internalize into live cells with high efficacy of gene transfection and low cytotoxicity. Increasing dendrimer generation increased their ability for gene transfection.
authors.affiliation: State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, 100029 Beijing, China.
authors.forename: Zejun
authors.initials: Z
authors.lastname: Xu
authors.forename: Bicheng
authors.initials: B
authors.lastname: He
authors.forename: Jie
authors.initials: J
authors.lastname: Shen
authors.forename: Wantai
authors.initials: W
authors.lastname: Yang
authors.forename: Meizhen
authors.initials: M
authors.lastname: Yin
mesh_terms: D000818:Animals; D001692:Biological Transport; D002460:Cell Line; D004247:DNA / Q000737:chemistry*; D050091:Dendrimers / Q000737:chemistry*; D004330:Drosophila; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry; D007094:Imides / Q000737:chemistry*; D010569:Perylene / Q000031:analogs & derivatives* / Q000737:chemistry; D012995:Solubility; D014162:Transfection; D014867:Water / Q000737:chemistry
chemical_list: D050091:Dendrimers; D005456:Fluorescent Dyes; D007094:Imides; C521332:perylenediimide; D014867:Water; D010569:Perylene; D004247:DNA