title: [Interferon treatment of chronic hepatitis C: basic immunobiology and immunopathology of the liver].
abstract: This article reviews the main aspects of chronic hepatitis C (epidemiological, genomic related to enhanced molecular understanding of the life cycle of the hepatitis C virus, HCV) especially standard therapy with pegilated interferon α and ribavirin. Emphasis is also placed on the immune response of the liver to HCV and the assessment of liver fibrosis via transient elastography.
authors.affiliation: Servicios Médicos, Centro Penitenciario Castellón II, Paraje Mascarell. javiermazana@telefonica.net
authors.forename: J S
authors.initials: JS
authors.lastname: Mazana
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D016903:Drug Monitoring; D004359:Drug Therapy, Combination; D054459:Elasticity Imaging Techniques; D020022:Genetic Predisposition to Disease; D019698:Hepatitis C, Chronic / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D008099:Liver / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology / Q000821:virology; D011092:Polyethylene Glycols / Q000627:therapeutic use*; D011994:Recombinant Proteins / Q000627:therapeutic use; D012254:Ribavirin / Q000627:therapeutic use; D013030:Spain / Q000453:epidemiology; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D016898:Interferon-alpha; D011994:Recombinant Proteins; D011092:Polyethylene Glycols; D012254:Ribavirin; C100416:peginterferon alfa-2a