title: Microvascular free flap reconstruction of orbitocraniofacial defects.
abstract: OBJECTIVE
  To examine the etiology, surgical extent and techniques, complications, and outcomes of microvascular free flaps (MFF) in the reconstruction of orbitocraniofacial defects.
  
  
  METHODS
  A retrospective, institutional review board approved study was performed of all patients undergoing MFF to repair orbitocraniofacial defects over 51 months.
  
  
  METHODS
  Fifty-eight patients undergoing MFF to repair orbitocraniofacial defects were included.
  
  
  METHODS
  Variables analyzed included demographics, etiology, resection area(s), donor site, flap size, duration of surgery, complications, length of hospital stay, flap survival, and mortality.
  
  
  RESULTS
  Fifty-eight patients underwent 61 MFFs from June 2007 to September 2011. The majority of patients were white (79.3%) and male (72.4%). The mean age was 64.1 years. The most common etiology was intraorbital and skull base extension of cutaneous squamous cell carcinoma (29.3%) followed by sinonasal squamous cell carcinoma (13.8%). Dura and/or brain were exposed in 44.8% of cases. MFFs were harvested from the anteriolateral thigh in 71.4% of cases with a 180.9 cm(2) mean flap area. The mean length of hospital stay was 15.3 days and mean length of surgical time was 11 h and 17 min.
  
  
  CONCLUSIONS
  Complex orbitocraniofacial defects require a multi-disciplinary team skilled in surgical extirpation and advanced reconstructive techniques. MFF should be considered in the management of large defects, especially when there is dura or brain exposure. Intensive postoperative monitoring is indicated for both systemic and flap-related complications. MMFs provide excellent coverage of large areas of exposed critical skull base structures, including dura and brain, and may allow for earlier adjuvant treatment.
authors.affiliation: Department of Otolaryngology-Head & Neck Surgery, Jefferson Medical College, Philadelphia, Pennsylvania, USA.
authors.forename: Ryan
authors.initials: R
authors.lastname: Heffelfinger
authors.forename: Ann P
authors.initials: AP
authors.lastname: Murchison
authors.forename: William
authors.initials: W
authors.lastname: Parkes
authors.forename: Howard
authors.initials: H
authors.lastname: Krein
authors.forename: Joseph
authors.initials: J
authors.lastname: Curry
authors.forename: James J
authors.initials: JJ
authors.lastname: Evans
authors.forename: Jurij R
authors.initials: JR
authors.lastname: Bilyk
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005153:Facial Neoplasms / Q000601:surgery*; D005260:Female; D058752:Free Tissue Flaps / Q000098:blood supply; D006801:Humans; D008297:Male; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures; D009918:Orbital Neoplasms / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000601:surgery*