title: Stroke care in young patients.
abstract: The aims of this study were (i) to evaluate the clinical features of a consecutive series of young patients with ischemic stroke and (ii) to assess the changes in the clinical management of these patients over the study period. All consecutive cases of young adults aged 16 to 44 years, with ischemic stroke, that were admitted between 2000 and 2005 in 10 Italian hospitals were included. We retrospectively identified 324 patients. One or more vascular risk factors were present in 71.5% of the patients. With respect to the diagnostic process, an increase in the frequency of cerebral noninvasive angiographic studies and a decrease in the use of digital subtraction angiography were observed (P < 0.001 and P = 0.03, resp.). Undetermined causes decreased over 5-year period of study (P < 0.001). The diagnosis of cardioembolism increased. Thrombolysis was performed for 7.7% of the patients. PFO closure (8%) was the most frequently employed surgical procedure. In conclusion, the clinical care that is given to young patients with ischemic stroke changed over the study period. In particular, we detected an evolution in the diagnostic process and a reduction in the number of undetermined cases.
authors.affiliation: Stroke Unit, Neurology Department, Azienda Ospedaliera Sant'Anna Hospital, Via Ravona 1, 22020 San Fermo della Battaglia, Como, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Tancredi
authors.forename: F
authors.initials: F
authors.lastname: Martinelli Boneschi
authors.forename: M
authors.initials: M
authors.lastname: Braga
authors.forename: I
authors.initials: I
authors.lastname: Santilli
authors.forename: C
authors.initials: C
authors.lastname: Scaccabarozzi
authors.forename: P
authors.initials: P
authors.lastname: Lattuada
authors.forename: M
authors.initials: M
authors.lastname: Sessa
authors.forename: L
authors.initials: L
authors.lastname: Fumagalli
authors.forename: S
authors.initials: S
authors.lastname: Iurlaro
authors.forename: I
authors.initials: I
authors.lastname: Neromante
authors.forename: M L
authors.initials: ML
authors.lastname: De Lodovici
authors.forename: D V
authors.initials: DV
authors.lastname: Roccatagliata
authors.forename: G
authors.initials: G
authors.lastname: Giacalone
authors.forename: M
authors.initials: M
authors.lastname: Arnaboldi
authors.forename: V
authors.initials: V
authors.lastname: Crespi
authors.forename: E
authors.initials: E
authors.lastname: Agostoni
authors.forename: G C
authors.initials: GC
authors.lastname: Comi
authors.forename: C
authors.initials: C
authors.lastname: Ferrarese
authors.forename: R
authors.initials: R
authors.lastname: Sterzi