title: Synthesis of novel isoquinolinone and 1,2-dihydroisoquinoline scaffolds via Ugi reaction and ring opening reaction of furans.
abstract: Combining the Ugi reaction with ring opening reaction of furans for the synthesis of novel isoquinolinone and 1,2-dihydroisoquinoline scaffolds has been developed. The isoquinolinone and 1,2-dihydroisoquinoline derivatives with unsaturated carbonyl moiety may open up many opportunities for further functionalizations.
authors.affiliation: Chemical Engineering College, Nanjing University of Science and Technology, Nanjing 210094, People's Republic of China.
authors.forename: Fei
authors.initials: F
authors.lastname: Ji
authors.forename: Wen-bin
authors.initials: WB
authors.lastname: Yi
authors.forename: Mu
authors.initials: M
authors.lastname: Sun
authors.forename: Mei-fang
authors.initials: MF
authors.lastname: Lv
authors.forename: Chun
authors.initials: C
authors.lastname: Cai
mesh_terms: D002384:Catalysis; D005663:Furans / Q000737:chemistry*; D007546:Isoquinolines / Q000138:chemical synthesis*; D010165:Palladium / Q000737:chemistry; D011500:Protein Synthesis Inhibitors / Q000138:chemical synthesis*; D015363:Quinolones / Q000138:chemical synthesis*
chemical_list: D005663:Furans; D007546:Isoquinolines; D011500:Protein Synthesis Inhibitors; D015363:Quinolones; D010165:Palladium