title: Large-diameter metal-on-metal total hip arthroplasties: a page in orthopedic history?
abstract: Large-diameter metal-on-metal (MoM) bearings evolved from the success of hip resurfacing. These implants were used in revision surgery in cases with well-fixed acetabular cups but loose or failed femoral stems, to avoid cup revision. Early data showed low rates of dislocation and potentially low wear profiles due to better fluid film lubrication. The risk of impingement was also thought to be low due to the increased head-neck ratio. Subsequently large-diameter MoM heads gained popularity in primary hip replacement. Recent data has emerged on the unacceptably high revision rates among patients with large-diameter MoM total hip arthroplasties (THAs), high blood levels of metal ions, and adverse tissue reactions. The head-neck (cone-taper) modular interface probably represents the weak link in large metal heads that have been used on conventional tapers. Increased torque of the large head, micromotion, and instability at the cone-taper interface, synergistic interactions between corrosion and wear, edge loading, low clearance, and psoas impingement are the likely causes for early failure of these prostheses.
authors.affiliation: Department of Orthopedic Surgery, Otto-Von-Guericke University, Leipziger Str. 44, D-39120, Magdeburg, Germany; University Orthopedics, Hand and Reconstructive Microsurgery Cluster, National University Health System, Singapore.
authors.forename: Gurpal
authors.initials: G
authors.lastname: Singh
authors.forename: Heiko
authors.initials: H
authors.lastname: Meyer
authors.forename: Marcel
authors.initials: M
authors.lastname: Ruetschi
authors.forename: Kathrin
authors.initials: K
authors.lastname: Chamaon
authors.forename: Bernd
authors.initials: B
authors.lastname: Feuerstein
authors.forename: Christoph H
authors.initials: CH
authors.lastname: Lohmann
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D049673:History, 20th Century; D006801:Humans; D007477:Ions; D061825:Metal-on-Metal Joint Prostheses / Q000009:adverse effects*; D009985:Orthopedics / Q000266:history*; D011474:Prosthesis Design; D011475:Prosthesis Failure
chemical_list: D007477:Ions
keywords: cone-taper interface; corrosion; large-diameter; metal-on-metal; total hip arthroplasty