title: A sensitive SERS assay of L-histidine via a DNAzyme-activated target recycling cascade amplification strategy.
abstract: A novel surface-enhanced Raman scattering (SERS) method is demonstrated to detect L-histidine based on DNAzyme which can specifically recognize L-histidine. Through a target recycling cascade amplification strategy, the DNAzyme-based SERS sensing system affords very high sensitivity for L-histidine with a detection limit of 0.56 nM.
authors.affiliation: Key Laboratory of Biochemical Analysis, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China.
authors.forename: Sujuan
authors.initials: S
authors.lastname: Ye
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Guo
authors.forename: Jie
authors.initials: J
authors.lastname: Xiao
authors.forename: Shusheng
authors.initials: S
authors.lastname: Zhang
mesh_terms: D004247:DNA / Q000737:chemistry; D021881:DNA, Catalytic / Q000737:chemistry*; D006639:Histidine / Q000032:analysis* / Q000737:chemistry; D013059:Spectrum Analysis, Raman
chemical_list: D021881:DNA, Catalytic; D006639:Histidine; D004247:DNA