title: Spontaneous closure of macular holes secondary to posterior uveitis: case series and a literature review.
abstract: The occurrence of a macular hole due to posterior uveitis is infrequently reported. We report the evolution of three cases of macular holes secondary to posterior segment inflammation. A complete inflammatory and infectious assessment found one case of toxocariasis, one of sarcoidosis, and one of syphilis. After medical etiological treatment, macular hole closure was rapidly obtained in all the cases and confirmed by spectral domain optic coherence tomography, with visual acuity improvement. Fibrous scarring developed in two cases, and foveal photoreceptor complex normalization was observed in the sarcoidosis case. These observations demonstrate that macular holes secondary to posterior uveitis frequently resolve without surgical intervention and so could be underdiagnosed if the patient is not evaluated at the time of onset before spontaneous hole closure.
authors.affiliation: Service d'Ophtalmologie, Pôle Médecine Interne-Ophtalmologie-ORL, CHU Clermont-Ferrand, Clermont-Ferrand, 63003, France. nicoasmo@yahoo.fr.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Bonnin
authors.forename: Pierre-Loïc
authors.initials: PL
authors.lastname: Cornut
authors.forename: Florian
authors.initials: F
authors.lastname: Chaise
authors.forename: Elodie
authors.initials: E
authors.lastname: Labeille
authors.forename: Helene Janin
authors.initials: HJ
authors.lastname: Manificat
authors.forename: Audrey
authors.initials: A
authors.lastname: Feldman
authors.forename: Laurent
authors.initials: L
authors.lastname: Perard
authors.forename: Franck
authors.initials: F
authors.lastname: Bacin
authors.forename: Frédéric
authors.initials: F
authors.lastname: Chiambaretta
authors.forename: Carole
authors.initials: C
authors.lastname: Burillon