title: Micromolecular multiple myeloma with chronic kidney failure in a young female patient on continuous hemodialysis.
abstract: The maximum incidence of multiple myeloma appears in the 6th-7th decade of life and although the number of patients aged les than 60 years is increasing in recent years, the diagnosis of a monoclonal gammopathy in a young patient, under the age of 40 years remains a rarity. Literature data cite an incidence of approximately 2.2% in patients less than 40-year-old and an incidence of 0.3% in patients less than 30-year-old of all cases diagnosed with multiple myeloma. We present the case of a 32-year-old patient, being on continuous hemodialysis for chronic kidney failure for about a year, at the Hematology Clinic of Craiova, Romania. We investigate the origin of a serum monoclonal component revealed when performing serum protein electrophoresis. Bone marrow examination revealed the presence of a plasma cell infiltrate of 18%, which associated with the presence of a serum monoclonal component and in the conditions of renal failure as a complication of the disease, has allowed the diagnosis of multiple myeloma.
authors.affiliation: Department of Hematology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania. rodirot@yahoo.com
authors.forename: Ionela
authors.initials: I
authors.lastname: Rotaru
authors.forename: M
authors.initials: M
authors.lastname: Badea
authors.forename: Alina Daniela
authors.initials: AD
authors.lastname: Tănase
authors.forename: Camelia
authors.initials: C
authors.lastname: Foarfă
mesh_terms: D000328:Adult; D001856:Bone Marrow Examination / Q000379:methods; D005260:Female; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy*; D009101:Multiple Myeloma / Q000097:blood / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology*; D006435:Renal Dialysis / Q000379:methods*