title: Ways in which SWL affects oxidant/antioxidant balance.
abstract: Many damages can occur in the kidneys following extracorporeal shock wave lithotripsy (SWL) and some of these damages are thought to emerge as a result of oxidative stress. The objective of this study is to evaluate the impact of SWL application on kidneys in stone patients on oxidative stress parameters in 24-h urine. The study included 20 patients scheduled for SWL. total antioxidant capacity (TAC) and total oxidant status (TOS) measurements were made on 24-h urines of the patients before and after SWL. The oxidative stress index (OSI) was calculated based on these values. Following SWL, while TOS increased in 24-h urine (p = 0.006), TAC remained unchanged (p = 0.312). OSI increased following the procedure (p = 0.004). SWL application disrupts the oxidant/antioxidant balance in favor of oxidants, which leads to oxidative stress. TOS, TAC and OSI may be useful in the determination of the existence of oxidative stress following SWL.
authors.affiliation: Department of Urology, Faculty of Medicine, University of Kirikkale, Tip Fakultesi, Uroloji AD, Saglik Sokak, 71100, Kirikkale, Turkey. erdaly69@mynet.com
authors.forename: Erdal
authors.initials: E
authors.lastname: Yilmaz
authors.forename: Ahmet
authors.initials: A
authors.lastname: Haciislamoglu
authors.forename: Ucler
authors.initials: U
authors.lastname: Kisa
authors.forename: Ozlem
authors.initials: O
authors.lastname: Dogan
authors.forename: Ercan
authors.initials: E
authors.lastname: Yuvanc
authors.forename: Ertan
authors.initials: E
authors.lastname: Batislam
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000378:metabolism*; D005260:Female; D006801:Humans; D007668:Kidney / Q000293:injuries* / Q000378:metabolism*; D007669:Kidney Calculi / Q000628:therapy; D008096:Lithotripsy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D016877:Oxidants / Q000378:metabolism; D018384:Oxidative Stress; D055815:Young Adult
chemical_list: D000975:Antioxidants; D016877:Oxidants