title: Short-term results of prolotherapy in the management of temporomandibular joint dislocation.
abstract: OBJECTIVE
  Prolotherapy, the rehabilitation of ligaments or tendons by induced proliferation of cells by using dextrose, is a noninvasive and effective method for the treatment of temporomandibular joint (TMJ) dislocation. The aim of this study was to evaluate the efficacy of prolotherapy method for the management of acute or chronic dislocation of TMJ.
  
  
  METHODS
  In this study, 10 patients with TMJ dislocation (2 acute, 8 chronic) were examined retrospectively. All patients consisted of female patients, with a mean age of 28.4, who were treated with prolotherapy procedure. Differences of visual analog scale scores in quality of life, pain on function, and chewing function efficacy between sessions were investigated using the Wilcoxon t test and median values of sessions were evaluated using the Kruskal-Wallis H test. The amount of change at the maximum mouth opening occurring between the preoperative and postoperative values and the frequency of locking episodes were calculated, with results considered statistically significant at P < 0.05.
  
  
  RESULTS
  Pain on function scores were significantly decreased in all patients, and TMJ locking were not observed during the follow-up period. Maximum mouth opening exhibited a tendency to decrease, but it was not statistically significant. Also, clicking sound on function presented no significant change (P > 0.05). On the other hand, the visual analog scale scores for quality of life showed significant improvement in all patients (P < 0.05).
  
  
  CONCLUSIONS
  The results of this study show that prolotherapy can be used as an efficient, simple, and conservative method to treat TMJ dislocation.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Karadeniz Technical University, Trabzon, Turkey. cem_ungor@yahoo.com
authors.forename: Cem
authors.initials: C
authors.lastname: Ungor
authors.forename: Kerem Turgut
authors.initials: KT
authors.lastname: Atasoy
authors.forename: Fatih
authors.initials: F
authors.lastname: Taskesen
authors.forename: Burak
authors.initials: B
authors.lastname: Cezairli
authors.forename: Ezher Hamza
authors.initials: EH
authors.lastname: Dayisoylu
authors.forename: Emre
authors.initials: E
authors.lastname: Tosun
authors.forename: Figen Cizmeci
authors.initials: FC
authors.lastname: Senel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D005947:Glucose / Q000627:therapeutic use*; D006801:Humans; D007270:Injections, Intra-Articular; D004204:Joint Dislocations / Q000188:drug therapy*; D008297:Male; D008409:Mastication; D008875:Middle Aged; D010147:Pain Measurement; D011788:Quality of Life; D016059:Range of Motion, Articular; D012189:Retrospective Studies; D013549:Sweetening Agents / Q000627:therapeutic use*; D013705:Temporomandibular Joint Disorders / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D013549:Sweetening Agents; D005947:Glucose