title: The destructive combination of Scediosporium apiosperum lung disease and exuberant inflammation in cystic fibrosis.
abstract: This paper describes a patient whose decline over two years was precipitous, from an active independent life with lung function (FEV1) above 50% to requiring transplantation. The main pathogen on sputum culture throughout that period was Scediosporium apiosperum. The epidemiology pathogenicity and treatment of this fungal pathogen are discussed.
authors.affiliation: Royal Brompton and Harefield NHS Foundation Trust. Georgina.Russell@rcplondon.ac.uk
authors.forename: Georgina K
authors.initials: GK
authors.lastname: Russell
authors.forename: Radha
authors.initials: R
authors.lastname: Gadhok
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Simmonds
mesh_terms: D000328:Adult; D003550:Cystic Fibrosis / Q000150:complications / Q000382:microbiology* / Q000601:surgery; D005260:Female; D006801:Humans; D016040:Lung Transplantation; D009181:Mycoses / Q000150:complications / Q000382:microbiology* / Q000601:surgery; D011014:Pneumonia / Q000382:microbiology* / Q000503:physiopathology / Q000601:surgery; D021681:Scedosporium / Q000302:isolation & purification*; D013183:Sputum / Q000382:microbiology