title: [Comparative evaluation of the efficiency of different magnetic resonance imaging procedures in the recognition of local recurrence of prostate cancer: preliminary results].
abstract: The paper considers the role of different procedures of magnetic resonance imaging (MRI) of a local recurrence of the disease in patients undergoing radical prostatectomy (RPE) for prostate cancer (PC). A study group comprised 12 patients who had developed a biochemical recurrence with no evidence of systemic progression of the disease in different periods after RPE. All the patients underwent multiphase MRI using T1-T2-weighted, diffusion-weighted, and postcontrast images. The MRI pattern of a cystourethral anastomotic area was analyzed from T2-weighted (T2-WI), diffusion-weighted (DWI), and postcontrast images (PCI) in all the patients. The local recurrence of PC was verified in them, using puncture biopsy under transrectal ultrasound guidance, by keeping in mind the MRI pattern. The use of DWI and postcontrast sequences was shown to substantially enhance the sensitivity of MRI in the diagnosis of local recurrences of PC as compared to an isolated analysis of T2WI (0.83, 0.67, and 0.42, respectively). Thus, in patients with a suspected local recurrence of PC after RPE, the visual estimate of DWI and PCI during small pelvic MRI makes it possible to considerably improve the recognition of a tumor nodule and to increase the efficiency of morphological verification of a recurrence of the disease.
authors.forename: V V
authors.initials: VV
authors.lastname: Kapustin
authors.forename: A I
authors.initials: AI
authors.lastname: Gromov
authors.forename: D S
authors.initials: DS
authors.lastname: Koshurnikov
mesh_terms: D000368:Aged; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis*; D011467:Prostate / Q000473:pathology* / Q000601:surgery; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000601:surgery; D012372:ROC Curve; D012189:Retrospective Studies