title: Steroidal saponins from Dracaena marginata.
abstract: Three new steroidal saponins and ten known ones were isolated from the bark of Dracaena marginata, along with two known steroidal saponins from the roots. Their structures were elucidated on the basis of extensive 1D and 2D NMR experiments and mass spectrometry as (25R)-26-(beta-D-glucopyranosyloxy)3beta,22alpha-dihydroxyfurost-5-en-1beta-yl O-alpha-L-rhamnopyranosyl-(1 --> 2)-[alpha-L-rhamnopyranosyl-(1 --> 4)]-beta-D-glucopyranoside (1), (25R)-26-(beta-D-glucopyranosyloxy)-3beta,22alpha-dihydroxyfurost-5-en-1beta-yl O-alpha-L-rhamnopyranosyl-(1 --> 2)-4-O-sulfo-alpha-L-arabinopyranoside (2), and (25S)-3beta-hydroxyspirost-5-en-1beta-yl O-alpha-L-rhamnopyranosyl-(1 --> 2)-4-O-sulfo-alpha-L-arabinopyranoside (3).
authors.affiliation: Laboratoire de Pharmacognosie, EA 4267, FDE / UFC, UFR Pharmacie, Université de Bourgogne, 7, Bd. Jeanne d'Arc, BP 87900, 21079 Dijon Cedex, France.
authors.forename: Abdelmalek
authors.initials: A
authors.lastname: Rezgui
authors.forename: Anne-Claire
authors.initials: AC
authors.lastname: Mitaine-Offer
authors.forename: David
authors.initials: D
authors.lastname: Pertuit
authors.forename: Tomofumi
authors.initials: T
authors.lastname: Miyamoto
authors.forename: Chiaki
authors.initials: C
authors.lastname: Tanaka
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Delemasure
authors.forename: Patrick
authors.initials: P
authors.lastname: Dutartre
authors.forename: Marie-Aleth
authors.initials: MA
authors.lastname: Lacaille-Dubois
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D031409:Dracaena / Q000737:chemistry*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D012503:Saponins