title: Association between chronic kidney disease and blood transfusions for knee and hip arthroplasty surgery.
abstract: The study aim is to assess associations between chronic kidney disease (CKD) and blood transfusions during hospitalization for joint arthroplasty. Patients with Stage IV-V CKD who underwent elective total knee or hip arthroplasty from 2007 to 2010 were matched 2:1 with age, gender, and surgery type controls without kidney disease. Multivariable analyses for transfusion risk with preoperative hemoglobin, body mass index, cardiovascular disease, and surgical complexity as explanatory variables were performed. Ninety CKD patients were identified and had lower preoperative hemoglobin, higher incidence of cardiovascular disease and blood transfusions. CKD was independently associated with increased odds of transfusions (2.88, 95% confidence interval 1.33-6.23, P=0.007). Preoperative optimization of CKD patients should be considered to reduce transfusion rates.
authors.affiliation: Department of Anesthesiology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
authors.forename: Ian D
authors.initials: ID
authors.lastname: Augustin
authors.forename: Tze Yeng
authors.initials: TY
authors.lastname: Yeoh
authors.forename: Juraj
authors.initials: J
authors.lastname: Sprung
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Berry
authors.forename: Darrell R
authors.initials: DR
authors.lastname: Schroeder
authors.forename: Toby N
authors.initials: TN
authors.lastname: Weingarten
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D019645:Arthroplasty, Replacement, Knee; D001803:Blood Transfusion / Q000706:statistics & numerical data*; D016022:Case-Control Studies; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D051436:Renal Insufficiency, Chronic / Q000097:blood / Q000150:complications; D012189:Retrospective Studies
chemical_list: D006454:Hemoglobins