title: Rhino-orbito-cerebral mucormycosis in patients with diabetic ketoacidosis.
abstract: Mucormycosis is a life-threatening fungal infection that occurs in immunocompromised patients. The most common predisposing risk factor for mucormycosis is diabetes mellitus. Rhino-orbito-cerebral mucormycosis is the most common form in diabetic patients and is characterized by paranasal sinusitis, ophthalmoplegia with blindness, and unilateral proptosis with cellulitis, facial pain with swelling, headache, fever, rhinitis, granular or purulent nasal discharge, nasal ulceration, epistaxis, hemiplegia or stroke, and decreased mental function. Diabetic ketoacidosis is the most common and serious acute complication of diabetic patients. We herein report 2 cases of fatal rhino-orbito-cerebral mucormycosis in a patient with diabetic ketoacidosis.
authors.affiliation: Department of Endocrinology and Metabolism, Mersin University Medical School, Mersin, Turkey.
authors.forename: Ramazan
authors.initials: R
authors.lastname: Gen
authors.forename: Elif Şahin
authors.initials: EŞ
authors.lastname: Horasan
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Vaysoğlu
authors.forename: Rabia Bozdoğan
authors.initials: RB
authors.lastname: Arpaci
authors.forename: Gülden
authors.initials: G
authors.lastname: Ersöz
authors.forename: Cengiz
authors.initials: C
authors.lastname: Özcan
mesh_terms: D000368:Aged; D016883:Diabetic Ketoacidosis / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000150:complications* / Q000382:microbiology; D009916:Orbital Diseases / Q000150:complications / Q000382:microbiology; D012220:Rhinitis / Q000150:complications / Q000382:microbiology; D012307:Risk Factors; D012852:Sinusitis / Q000150:complications / Q000382:microbiology; D014081:Tooth Extraction