title: [Diagnosis of isolated angiitis of the central nervous system].
abstract: We have analyzed clinical presentations, neuroimaging data, blood and cerebrospinal fluid diagnostic tests in isolated angiitis of the central nervous system on the basis of data of recent publications and 22 our own cases. Due to the insufficient diagnostic value of invasive methods including biopsy of leptomeningeal and intracerebral vessels, we considered practical approaches to the diagnosis of cerebral vasculitis and ways of its optimization. We suggested the stratification of clinical, neuroimaging and laboratory criteria for the evaluation of their sensitivity and specificity and for the development of diagnostic algorithms.
authors.forename: N A
authors.initials: NA
authors.lastname: Totolian
authors.forename: A A
authors.initials: AA
authors.lastname: Totovchikov
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Kodzaeva
authors.forename: V S
authors.initials: VS
authors.lastname: Krasnov
authors.forename: S V
authors.initials: SV
authors.lastname: Lapin
authors.forename: A A
authors.initials: AA
authors.lastname: Skoromets
mesh_terms: D000328:Adult; D000465:Algorithms; D001921:Brain / Q000473:pathology*; D002536:Cerebral Arteries / Q000473:pathology*; D002550:Cerebral Veins / Q000473:pathology*; D003937:Diagnosis, Differential; D018450:Disease Progression; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D013116:Spinal Cord / Q000473:pathology*; D020293:Vasculitis, Central Nervous System / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D055815:Young Adult