title: Extracorporeal renal replacement therapy and blood purification in critical care.
abstract: OBJECTIVE
  To review indications methods of renal replacement therapies (RRT) and practical considerations for the creation of a RRT program.
  
  
  METHODS
  Current human and veterinary literature review with a focus on advanced renal physiology and clinical experience in RRT and acute/chronic kidney diseases.
  
  
  RESULTS
  Renal replacement therapies encompass intermittent hemodialysis, continuous renal replacement therapy as well as some "hybrid" techniques. Each method of RRT has practical and theoretical advantages but currently there is no evidence that one technique is superior to the other.
  
  
  CONCLUSIONS
  RRT is a valuable therapeutic tool for treatment of acute kidney injury and chronic kidney disease. The implementation of an RRT program needs to take into consideration multiple parameters beyond the choice of an RRT platform.
authors.affiliation: Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. ldcowgill@ucdavis.edu
authors.forename: Larry D
authors.initials: LD
authors.lastname: Cowgill
authors.forename: Julien
authors.initials: J
authors.lastname: Guillaumin
mesh_terms: D000818:Animals; D003422:Critical Care / Q000379:methods*; D017582:Renal Replacement Therapy / Q000379:methods / Q000592:standards / Q000662:veterinary*