title: [Radiofrequency ablation of hepatocellular carcinoma].
abstract: Percutaneous radiofrequency ablation (RFA) is well established in the treatment of hepatocellular carcinoma (HCC). Due to its curative potential, it is the method of choice for non resectable BCLC (Barcelona Liver Clinic) 0 and A. RFA challenges surgical resection for small HCC and is the method of choice in bridging for transplantation and recurrence after resection or transplantation. The technical feasibility of RFA depends on the size and location of the HCC and the availability of ablation techniques (one needle techniques, multi-needle techniques). More recently, stereotactic multi-needle techniques with 3D trajectory planning and guided needle placement substantially improve the spectrum of treatable lesions including large volume tumors. Treatment success depends on the realization of ablations with large intentional margins of tumor free tissue (A0 ablation in analogy to R0 resection), which has to be documented by fusion of post- with pre-ablation images, and confirmed during follow-up imaging.
authors.affiliation: Abteilung für Mikroinvasive Therapie, Universitätsklinik für Radiologie, Medizinische Universität Innsbruck, Anichstr. 35, 6020 Innsbruck, Österreich. gerlig.widmann@i-med.ac.at
authors.forename: Gerlig
authors.initials: G
authors.lastname: Widmann
authors.forename: Peter
authors.initials: P
authors.lastname: Schullian
authors.forename: Reto
authors.initials: R
authors.lastname: Bale
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D017115:Catheter Ablation / Q000379:methods*; D005240:Feasibility Studies; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D021621:Imaging, Three-Dimensional; D008113:Liver Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D015996:Survival Rate; D014057:Tomography, X-Ray Computed; D047368:Tumor Burden