title: NHC-catalyzed reaction of enals with hydroxy chalcones: diastereoselective synthesis of functionalized coumarins.
abstract: The N-heterocyclic carbene-catalyzed annulation of enals with 2'-hydroxy chalcones afford cyclopentane-fused coumarin derivatives with an excellent level of diastereocontrol. The reaction tolerates a broad range of functional groups; 25 examples are given, and a preliminary mechanistic investigation is provided.
authors.affiliation: Organic Chemistry Division, CSIR-National Chemical Laboratory, Dr. Homi Bhabha Road, Pune 411008, India.
authors.forename: Anup
authors.initials: A
authors.lastname: Bhunia
authors.forename: Atanu
authors.initials: A
authors.lastname: Patra
authors.forename: Vedavati G
authors.initials: VG
authors.lastname: Puranik
authors.forename: Akkattu T
authors.initials: AT
authors.lastname: Biju