title: Protein-coated nanocapsules via multilevel surface modification. Controlled preparation and microscopic analysis at nanometer resolution.
abstract: We prepared self-assembled vesicles comprising layers of fullerene, alkyl chains, triazole, oligo(ethylene oxide) chains, biotin and avidin molecules. High-resolution scanning electron microscopy using a superhydrophilic indium-tin oxide substrate was found to be useful for nanometer-level structural analysis of the vesicles and individual avidin molecules whose structures are difficult to analyze.
authors.affiliation: Department of Chemistry, The University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Harano
authors.forename: Kosuke
authors.initials: K
authors.lastname: Minami
authors.forename: Eisei
authors.initials: E
authors.lastname: Noiri
authors.forename: Koji
authors.initials: K
authors.lastname: Okamoto
authors.forename: Eiichi
authors.initials: E
authors.lastname: Nakamura
mesh_terms: D001360:Avidin / Q000737:chemistry*; D001710:Biotin / Q000737:chemistry*; D003300:Copper / Q000737:chemistry; D004317:Doxorubicin / Q000737:chemistry; D037741:Fullerenes / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D053769:Nanocapsules / Q000737:chemistry* / Q000648:ultrastructure
chemical_list: D037741:Fullerenes; D053769:Nanocapsules; D001360:Avidin; D001710:Biotin; D003300:Copper; D004317:Doxorubicin