title: 68Ga-DOTANOC PET-CT demonstrating in vivo somatostatin receptor expression in idiopathic gynecomastia.
abstract: Gynecomastia is abnormal enlargement of the male breasts due to the excess growth of glandular component. A 65-year-old man with medullary carcinoma of thyroid underwent (68)Ga-DOTANOC PET-CT for somatostatin receptor (SSTR) scintigraphy. Extensive nodal, bone, and bone marrow disease was seen. Interestingly, increased (68)Ga-DOTANOC uptake was also noted in bilateral enlarged mammary glands (gynecomastia). Although SSTR types 1 and 3 have been identified in the normal female breast, no report exists regarding SSTR expression in gynecomastia.
authors.affiliation: Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Varun Singh
authors.initials: VS
authors.lastname: Dhull
authors.forename: Punit
authors.initials: P
authors.lastname: Sharma
authors.forename: Suhas
authors.initials: S
authors.lastname: Singla
authors.forename: Abhinav
authors.initials: A
authors.lastname: Singhal
authors.forename: Chandrasekhar
authors.initials: C
authors.lastname: Bal
authors.forename: Rakesh
authors.initials: R
authors.lastname: Kumar
mesh_terms: D000368:Aged; D015972:Gene Expression Regulation, Neoplastic; D006177:Gynecomastia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism; D006801:Humans; D008297:Male; D064847:Multimodal Imaging; D009942:Organometallic Compounds; D049268:Positron-Emission Tomography; D017481:Receptors, Somatostatin / Q000378:metabolism*; D014057:Tomography, X-Ray Computed
chemical_list: C504894:68Ga-DOTANOC; D009942:Organometallic Compounds; D017481:Receptors, Somatostatin