title: Outcome of total hip arthroplasty as a salvage procedure for failed infected internal fixation of hip fractures.
abstract: BACKGROUND
  Failed infected internal fixation produces significant pain and functional disability. In infected internal fixation of hip fractures with partial or complete head destruction, total hip arthroplasty (THA) can be technically challenging; however, it restores hip biomechanics. The present study is to evaluate the results and assess the complications of THA following failed infected internal fixation of these fractures.
  
  
  METHODS
  A retrospective review of prospectively collected data in a tertiary healthcare center was performed of 20 consecutive patients of THA following failed infected internal fixation operated between September 2001 and November 2007. There were 11 dynamic hip screw failures for intertrochanteric fractures, 6 failed osteotomies following transcervical fractures, and 3 failed screw fixations for transcervical fractures.
  
  
  RESULTS
  The average age of the patients was 48.5 years (range 28-70 years) and the average followup period was 6.5 years (range 3.5-10.5 years). An indigenously designed cement spacer was used in a majority of patients (n = 15). The custom-made antibiotic impregnated cement spacer was prepared on-table, with the help of a K-nail bent at 130°, long stem Austin Moore's prosthesis (n=1), Charnley's prosthesis (n=1), or bent Rush nail (n=1). The antibiotic mixed cement was coated over the hardware in its doughy phase and appropriately shaped using an asepto syringe or an indigenously prepared spacer template. Nineteen of the 20 patients underwent two-stage revision surgeries. The average Harris hip score improved from 35.3 preoperatively to 82.85 postoperatively at the last followup. A significant difference was found (P < 0.0001). None of the patients had recurrence of infection.
  
  
  CONCLUSIONS
  The results were comparable to primary arthroplasty in femoral neck fractures. Thus, THA is a useful salvage procedure for failed infected internal fixation of hip fractures.
authors.affiliation: Department of Orthopaedics, Seth G.S. Medical College and K.E.M. Hospital, Parel, Mumbai, India.
authors.forename: Shubhranshu S
authors.initials: SS
authors.lastname: Mohanty
authors.forename: Mandar V
authors.initials: MV
authors.lastname: Agashe
authors.forename: Binoti A
authors.initials: BA
authors.lastname: Sheth
authors.forename: Kumar K
authors.initials: KK
authors.lastname: Dash
keywords: Hip fracture; antibiotic spacer; failed internal fixation; infection; total hip arthroplasty