title: Pd-catalyzed multidehydrogenative cross-coupling between (hetero)arenes and nitroethane to construct β-aryl nitroethylenes.
abstract: The Pd-catalyzed multidehydrogenative cross-coupling reactions of arenes with nitroethane are described. The established methods afford β-aryl nitroethylenes that are an important class of synthetic intermediates and biologically active compounds in an atom- and step-economical fashion. The reactions were applicable to substituted benzenes and a variety of heterocycles such as benzothiophenes, benzofurans, and indoles. Mechanistic experiments indicated that β-nitroethylbenzene might be the intermediate in this transformation.
authors.affiliation: State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, China.
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.forename: Peng
authors.initials: P
authors.lastname: Hu
authors.forename: Jun
authors.initials: J
authors.lastname: Zhou
authors.forename: Ge
authors.initials: G
authors.lastname: Wu
authors.forename: Shijun
authors.initials: S
authors.lastname: Huang
authors.forename: Weiping
authors.initials: W
authors.lastname: Su