title: PAMAM dendrimer roles in gene delivery methods and stem cell research.
abstract: Nanotechnology has provided new technological opportunities, which could help in challenges confronting stem cell research. Polyamidoamine (PAMAM) dendrimers, a new class of macromolecular polymers with high molecular uniformity, narrow molecular distribution specific size and shape and highly functionalised terminal surface have been extensively explored for biomedical application. PAMAM dendrimers are also nanospherical, hyperbranched and monodispersive molecules exhibiting exclusive properties which make them potential carriers for drug and gene delivery.
authors.affiliation: Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
authors.forename: Nasibeh
authors.initials: N
authors.lastname: Daneshvar
authors.forename: Rasedee
authors.initials: R
authors.lastname: Abdullah
authors.forename: Fatemeh T
authors.initials: FT
authors.lastname: Shamsabadi
authors.forename: Chee Wun
authors.initials: CW
authors.lastname: How
authors.forename: M Aizat
authors.initials: MA
authors.lastname: Mh
authors.forename: Parvaneh
authors.initials: P
authors.lastname: Mehrbod
mesh_terms: D065150:Cellular Reprogramming; D050091:Dendrimers / Q000737:chemistry*; D018014:Gene Transfer Techniques; D057026:Induced Pluripotent Stem Cells / Q000166:cytology / Q000378:metabolism; D036103:Nanotechnology; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D050091:Dendrimers; C104700:PAMAM Starburst; D014157:Transcription Factors