title: [Muscle atrophy caused by limited mobilisation].
abstract: BACKGROUND
  Immobilisation and limited mobilisation are associated with negative adaptations of human body, like elevated risk for thrombosis, reduced fitness level and muscle atrophy. The objective of the presented study was to investigate the effect of limited, reduced mobility of a few days on the upper leg muscles.
  
  
  METHODS
  32 patients who underwent an elective arthroscopic surgery of the knee because of meniscus tear and/or cartilage damage were examined preoperatively and at days 4 and 7 after surgery. Examinations of the not injured and not treated leg focused on measurements of leg circumference and maximum strength of M. quadriceps femoris.
  
  
  RESULTS
  The measurements of circumferences of the upper leg at 20 cm above the knee joint line decreased significantly between preoperative and both postoperative examinations. Also the changing of circumference of the upper leg at 10 cm above the joint line between preoperative and day 4 postoperative was significant. The circumference of lower leg and strength measurements showed no significant changing.
  
  
  CONCLUSIONS
  Limited, reduced mobility lasting a few days is followed by reduction of muscle cross section of load bearing upper leg muscles.
authors.affiliation: 2. Medizinische Klinik und Poliklinik, Universitätsmedizin Mainz, 55131 Mainz. karsten.keller@unimedizin-mainz.de
authors.forename: K
authors.initials: K
authors.lastname: Keller
authors.forename: M
authors.initials: M
authors.lastname: Engelhardt
mesh_terms: D005260:Female; D006801:Humans; D007103:Immobilization / Q000009:adverse effects* / Q000379:methods*; D007718:Knee Injuries / Q000503:physiopathology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction; D053580:Muscle Strength; D009133:Muscular Atrophy / Q000209:etiology* / Q000503:physiopathology*; D009929:Organ Size; D016896:Treatment Outcome