title: [Renal denervation. Current developments].
abstract: METHODICAL INNOVATION: Renal denervation is a catheter-based, endovascular procedure for the treatment of drug-resistant hypertension. The aim of the therapy is to lower the blood pressure < 140/90 mmHg.
  
  
  METHODS
  Even after successful minimally invasive therapy patients usually continue to take three or more antihypertensive drugs. Currently there is no evidence that renal denervation is a good option for the treatment of well-controlled hypertension in order to dispense with antihypertensive drugs. In carefully selected patients the mean reduction in systolic and diastolic blood pressure after renal denervation is 25-30 mmHg and 10-15 mmHg, respectively.
  
  
  RESULTS
  Procedure-related or device-related complications are rare. Ablation catheters from different manufactures differ greatly in handling properties; however, up to now there is no evidence for relevant differences in safety and efficacy between the devices available.
authors.affiliation: Institut für Diagnostische und Interventionelle Radiologie und Kinderradiologie, Klinikum Schwabing, Kölner Platz 1, Munich, Germany. andreas.saleh@klinikum-muenchen.de
authors.forename: A
authors.initials: A
authors.lastname: Saleh
mesh_terms: D003714:Denervation / Q000379:methods* / Q000639:trends; D006801:Humans; D006977:Hypertension, Renal / Q000175:diagnosis* / Q000601:surgery*; D007668:Kidney / Q000294:innervation* / Q000601:surgery*; D025321:Surgery, Computer-Assisted / Q000379:methods* / Q000639:trends