title: Indomethacin-related leukocytoclastic vasculitis: a case report and review of literature.
abstract: Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis with a reported incidence rate of 30 cases per million persons per year. It usually presents as a palpable purpuric skin rash on legs, though any part of the body can be affected. LCV rash may have an associated burning sensation or pain and in some cases may involve internal organs. In some cases, LCV rash may present as nodules, recurrent ulcerations or asymptomatic lesions. The diagnosis of LCV is usually made on skin biopsy. Etiological triggers may not be identified in as many as half of the cases. Treatment is usually conservative and includes identification and removal or treatment of the etiological trigger except in cases with internal organ involvement where systemic steroids and immunosuppressant may be necessary. In this article we present a case of indomethacin-associated LCV that improved with discontinuation of the offending agent.
authors.affiliation: Department of Internal Medicine, Saint Joseph Hospital, Chicago, Ill., USA.
authors.forename: Nasir
authors.initials: N
authors.lastname: Hussain
authors.forename: Usman
authors.initials: U
authors.lastname: Mustafa
authors.forename: James
authors.initials: J
authors.lastname: Davis
authors.forename: Shivani
authors.initials: S
authors.lastname: Thakkar
authors.forename: Alaa M
authors.initials: AM
authors.lastname: Ali
authors.forename: Aibek E
authors.initials: AE
authors.lastname: Mirrakhimov
authors.forename: Aram
authors.initials: A
authors.lastname: Barbaryan
authors.forename: Guy Anthony
authors.initials: GA
authors.lastname: Rowley
keywords: Ceretec scan; Indomethacin; Leukocytoclastic vasculitis