title: Dendritic closomers: novel spherical hybrid dendrimers.
abstract: We report construction of monodisperse PAMAM-type dendrimers based on a dodecahydroxy closo-dodecaborane scaffold. The ideal sphericity and high functional group density of the icosahedral core permits ready access to hybrid dendrimers (dendritic closomers) having rigid, uniformly shaped exterior surfaces.
authors.affiliation: International Institute of Nano and Molecular Medicine, University of Missouri, 1514 Research Park Drive, Columbia, MO 65211, USA.
authors.forename: Alexei
authors.initials: A
authors.lastname: Pushechnikov
authors.forename: Satish S
authors.initials: SS
authors.lastname: Jalisatgi
authors.forename: M Frederick
authors.initials: MF
authors.lastname: Hawthorne
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000737:chemistry; D001880:Boranes / Q000737:chemistry; D050091:Dendrimers / Q000737:chemistry*; D004317:Doxorubicin / Q000737:chemistry; D004337:Drug Carriers / Q000737:chemistry
chemical_list: D000903:Antibiotics, Antineoplastic; D001880:Boranes; D050091:Dendrimers; D004337:Drug Carriers; C104700:PAMAM Starburst; D004317:Doxorubicin