title: MUSTN1 mRNA Abundance and Protein Localization is Greatest in Muscle Tissues of Chinese Meat-Quality Chickens.
abstract: The Mustang, Musculoskeletal Temporally Activated Novel-1 Gene (MUSTN1) plays an important role in regulating musculoskeletal development in mammals. We evaluated the developmental and tissue-specific regulation of MUSTN1 mRNA and protein abundance in Erlang Mountainous (EM) chickens. Results indicated that MUSTN1 mRNA/protein was expressed in most tissues with especially high expression in heart and skeletal muscle. The MUSTN1 protein localized to the nucleus in myocardium and skeletal muscle fibers. There were significant differences in mRNA and protein abundance among tissues, ages and between males and females. In conclusion, MUSTN1 was expressed the greatest in skeletal muscle where it localized to the nucleus. Thus, in chickens MUSTN1 may play a vital role in muscle development.
authors.affiliation: College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, Sichuan, China. zhuqing5959@163.com.
authors.forename: Juan
authors.initials: J
authors.lastname: Li
authors.forename: Yang
authors.initials: Y
authors.lastname: Chen
authors.forename: Ya-Gang
authors.initials: YG
authors.lastname: Wang
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Zhao
authors.forename: Elizabeth Ruth
authors.initials: ER
authors.lastname: Gilbert
authors.forename: Yi-Ping
authors.initials: YP
authors.lastname: Liu
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.forename: Yao-Dong
authors.initials: YD
authors.lastname: Hu
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhu