title: [A case of late recurrent breast cancer that responded to radiation therapy and cisplatin plus pemetrexed therapy].
abstract: The patient was a 62-year-old woman who had undergone modified radical mastectomy for right breast cancer 19 years before. She was examined at our hospital for cough and hoarseness. After PET-CT and bronchoscopy, she was diagnosed with stage IIIB non-small cell lung cancer. Radiation therapy and cisplatin plus pemetrexed therapy were effective, and she made a recovery from a life-threatening conditon. During observation, a skin nodule was noticed on her right chest wall, and excisional biopsy revealed a skin metastasis from breast cancer. A transbronchial lung biopsy(TBLB)specimen was reexamined, and the lung lesion was shown to be metastasis from breast cancer. By changing to endocrine therapy, the disease has been effectively controlled.
authors.affiliation: Dept. of Breast Surgery, Hiroshima Prefectural Hospital, Japan.
authors.forename: Etsushi
authors.initials: E
authors.lastname: Akimoto
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ohara
authors.forename: Midori
authors.initials: M
authors.lastname: Noma
authors.forename: Masakazu
authors.initials: M
authors.lastname: Kamitsuna
authors.forename: Takashi
authors.initials: T
authors.lastname: Nishizaka
authors.forename: Toshiyuki
authors.initials: T
authors.lastname: Itamoto
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000628:therapy*; D002289:Carcinoma, Non-Small-Cell Lung / Q000175:diagnosis* / Q000628:therapy*; D059248:Chemoradiotherapy; D002945:Cisplatin / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005260:Female; D005971:Glutamates / Q000008:administration & dosage; D006147:Guanine / Q000008:administration & dosage / Q000031:analogs & derivatives; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary / Q000628:therapy*; D008875:Middle Aged; D000068437:Pemetrexed; D012008:Recurrence; D012878:Skin Neoplasms / Q000556:secondary / Q000628:therapy*
chemical_list: D005971:Glutamates; D000068437:Pemetrexed; D006147:Guanine; D002945:Cisplatin