title: Long-term outcome of one-piece implants. Part I: implant characteristics and loading protocols. A systematic literature review with meta-analysis.
abstract: OBJECTIVE
  The aim of this systematic review was to evaluate the long-term clinical performance of one-piece implants.
  
  
  METHODS
  An electronic MEDLINE search complemented by a manual search was conducted to identify randomized and prospective cohort studies on one-piece implants. Additional inclusion criteria were: a mean follow-up period of at least 5 years and an inception cohort where more than 80% of the enrolled patients remained in the study at the 5- or 10-year observation point.
  
  
  RESULTS
  Sixty-six studies from an initial yield of 597 titles were selected, and the data were extracted. Of the full-text articles examined, 46 were excluded from the final analysis. A total of 20 articles were finally selected. All studies were published between 1995 and 2011. Two different study designs were included: 4 randomized controlled trials and 16 prospective cohort studies. The studies were analyzed and classified according to the follow-up period, the type of implant surface, the type of edentulism, the type of loading protocol, and the type of setting. The meta-analysis of the included studies showed an implant survival rate for one-piece, one-part implants of 96.79% (95% CI: 94.04% to 98.71%) after 5 years. In one-piece, two-part implants, the survival rate was slightly higher: 98.16% (95% CI: 96.48% to 99.31%) after 5 years and 96.83% (95% CI: 93.12% to 99.24%) after 10 years.
  
  
  CONCLUSIONS
  Within the limits of this systematic review, it can be concluded that high long-term survival rates can be observed with one-piece implants. Further randomized clinical trials are needed to provide more information about the outcome of different variables associated with one-piece implants.
authors.affiliation: Department of Prosthodontics, School of Dentistry, Freiburg, Germany. jose.maria.barrachina.diez@uniklinik-freiburg.de
authors.forename: Jose M
authors.initials: JM
authors.lastname: Barrachina-Diez
authors.forename: Esam
authors.initials: E
authors.lastname: Tashkandi
authors.forename: Susanne
authors.initials: S
authors.lastname: Stampf
authors.forename: Wael
authors.initials: W
authors.lastname: Att
mesh_terms: D059605:Dental Implant-Abutment Design / Q000379:methods*; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D019250:Dental Implants, Single-Tooth; D017267:Dental Prosthesis Design / Q000379:methods; D019232:Dental Restoration Failure / Q000706:statistics & numerical data*; D006801:Humans; D057893:Immediate Dental Implant Loading; D007576:Jaw, Edentulous, Partially / Q000534:rehabilitation; D008334:Mandible; D008437:Maxilla; D009066:Mouth, Edentulous / Q000534:rehabilitation; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D013499:Surface Properties; D000078202:Systematic Reviews as Topic; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants