title: Topological features in stretching of proteins.
abstract: In the present article, we highlight the diversity of mechanical clamps, some of them topological in nature, that have been found by making surveys of mechanostability of approximately 18000 proteins within structure-based models. The existence of superstable proteins (with the characteristic unfolding force in the region of 1000 pN) is predicted.
authors.affiliation: Laboratory of Biological Physics, Institute of Physics, Polish Academy of Sciences, Al. Lotnikow 32/48, Warsaw, Poland. mc@ifpan.edu.pl
authors.forename: Marek
authors.initials: M
authors.lastname: Cieplak
authors.forename: Mateusz
authors.initials: M
authors.lastname: Sikora
mesh_terms: D000818:Animals; D006801:Humans; D008958:Models, Molecular; D011487:Protein Conformation; D055550:Protein Stability; D011506:Proteins / Q000737:chemistry*
chemical_list: D011506:Proteins