title: [Obstructive sleep apnoea syndrome in patients with acute myocardial infarction: the efficacy of treatment and risk factors].
abstract: The study included 112 patients with acute myocardial infarction and elevated ST segment on ECG depending on the presence of obstructive sleep apnoea syndrome (OSAS). Dynamic analysis clinico-instrumental characteristics after the hospital-based treatment revealed insufficient reduction of ST segment by day 14 of therapy that correlated with severity of the disease estimated from the apnoea/hypopnoea index. Only these patients responded to the treatment by a decrease of the left ventricular ejection fraction as a marker of systolic dysfunction. Apnoea/hypopnoea index over 15 episodes/hr, the history of diabetes mellitus and anterior myocardial infarction were the most significant factors determining the relative risk of OSAS influence on the development of myocardial infarction. The authors emphasize the importance of early diagnostics of OSAS in patients with acute myocardial infarction and the necessity of cardiorespiratory monitoring in addition to hemodynamic one.
authors.forename: A P
authors.initials: AP
authors.lastname: Ivanov
authors.forename: D V
authors.initials: DV
authors.lastname: Kliuvkin
authors.forename: V V
authors.initials: VV
authors.lastname: Rostorotskaia
authors.forename: I A
authors.initials: IA
authors.lastname: El'gardt
mesh_terms: D000368:Aged; D004562:Electrocardiography; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D017286:Polysomnography; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D015912:Thrombolytic Therapy / Q000379:methods*; D016896:Treatment Outcome