title: [Effect of fenugreek on the growth of different genesis tumors].
abstract: This paper deals with antitumor properties of a fenugreek (Trigonella Foenum Graecum L.) as to the different genesis tumors--the Ca755 mouse mammary carcinoma and the Guerin's carcinoma in rats. Fenugreek powder was shown to inhibit (25-40 %) growth of certain tumors, decrease (27-63%) level of malone dialdehyde in liver, heart and kidney. Consumption of fenugreek was accompanied with decreased polyamines (spermine, spermidine, putrescine) content in tumor tissue. Inclusion of fenugreek to allowance was shown to improve certain blood value.
authors.forename: V V
authors.initials: VV
authors.lastname: Zhilenko
authors.forename: S P
authors.initials: SP
authors.lastname: Zalietok
authors.forename: O O
authors.initials: OO
authors.lastname: Klenov
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology / Q000627:therapeutic use*; D002277:Carcinoma / Q000188:drug therapy* / Q000378:metabolism; D002945:Cisplatin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D019008:Drug Resistance, Neoplasm / Q000187:drug effects; D005260:Female; D006321:Heart / Q000187:drug effects; D007668:Kidney / Q000187:drug effects / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008315:Malondialdehyde / Q000378:metabolism; D008325:Mammary Neoplasms, Experimental / Q000188:drug therapy* / Q000378:metabolism; D051379:Mice; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage; D028321:Plant Preparations / Q000494:pharmacology / Q000627:therapeutic use*; D011208:Powders / Q000494:pharmacology / Q000627:therapeutic use*; D011700:Putrescine / Q000037:antagonists & inhibitors; D051381:Rats; D013095:Spermidine / Q000037:antagonists & inhibitors; D013096:Spermine / Q000037:antagonists & inhibitors; D029910:Trigonella / Q000737:chemistry*; D047368:Tumor Burden / Q000187:drug effects
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts; D028321:Plant Preparations; D011208:Powders; D013096:Spermine; D008315:Malondialdehyde; C056164:fenugreek seed meal; D004317:Doxorubicin; D002945:Cisplatin; D013095:Spermidine; D011700:Putrescine