title: Parry Romberg syndrome associated with chronic facial pain.
abstract: Parry Romberg Syndrome (PRS) is a rare condition of unknown cause and pathophysiology. It is characterized by progressive facial hemiatrophy, and neurological abnormalities are found in 20% of cases. We describe a 50-year-old woman with PRS and severe neurological involvement (lateralised epileptic seizure activity and facial pain refractory to medication). Pain intensity and frequency was reduced and control of epileptic crises was improved using levetiracetam as an additional therapy. In previous published cases associated with facial pain, the most frequent diagnoses were migraine and trigeminal neuralgia. Our findings suggest that in this patient PRS-related persistent pain has peculiar features possibly attributed to the underlying musculoskeletal abnormalities.
authors.affiliation: Department of Neurology, San Raffaele Scientific Institute, via Olgettina 48, 20132 Milan, Italy. gloria.dallacosta@gmail.com
authors.forename: Gloria
authors.initials: G
authors.lastname: Dalla Costa
authors.forename: Bruno
authors.initials: B
authors.lastname: Colombo
authors.forename: Dacia
authors.initials: D
authors.lastname: Dalla Libera
authors.forename: Vittorio
authors.initials: V
authors.lastname: Martinelli
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Comi
mesh_terms: D059350:Chronic Pain / Q000150:complications / Q000175:diagnosis*; D005150:Facial Hemiatrophy / Q000150:complications / Q000175:diagnosis*; D005157:Facial Pain / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008875:Middle Aged
keywords: Chronic facial pain; PRS; Parry Romberg Syndrome; Progressive facial hemiatrophy