title: Diabetes in cystic fibrosis.
abstract: Cystic fibrosis related diabetes (CFRD) is a common complication of cystic fibrosis, caused by a fall in insulin secretion with age in individuals with pancreatic insufficiency. CFRD is associated with worse clinical status and increased mortality. Treatment of CFRD with insulin results in sustained improvements in lung function and nutrition. While clinical experience with insulin treatment in CF has increased, the selection of who to treat and glycaemic targets remain unclear.
authors.affiliation: Chelsea and Westminster Hospital, London SW10 9NH.
authors.forename: Nicola
authors.initials: N
authors.lastname: Bridges
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D003550:Cystic Fibrosis / Q000150:complications* / Q000188:drug therapy; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000209:etiology*; D018149:Glucose Intolerance; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000627:therapeutic use*
chemical_list: D001786:Blood Glucose; D007328:Insulin