title: Motor Axonal Neuropathy Associated With Idiopathic CD4(+) T-Lymphocytopenia.
abstract: Idiopathic CD4(+) T-lymphocytopenia is a rare immune disorder characterized by an unexplained deficit of CD4(+) T cells and results in various opportunistic infections. Herein, we report a case of new onset weakness in a 10-year-old boy secondary to motor axonal neuropathy associated with idiopathic CD4(+) T-lymphocytopenia. The patient was referred to rehabilitation for an evaluation of progressive weakness involving all four limbs. A subsequent nerve conduction study and needle electromyography identified motor axonal neuropathy. At that time, laboratory studies specific to the differential diagnosis of motor axonal neuropathy were performed; however, the abnormality noted was a decreased CD4(+) T-lymphocyte count. Motor axonal neuropathy represents an uncommon manifestation of idiopathic CD4(+) T-lymphocytopenia and is probably associated with an underlying immune process.
authors.affiliation: Department of Rehabilitation Medicine, Daejin Medical Center Bundang Jesaeng General Hospital, Seongnam, Korea.
authors.forename: Tae Im
authors.initials: TI
authors.lastname: Yi
authors.forename: Bo Ra
authors.initials: BR
authors.lastname: Kim
authors.forename: In Soo
authors.initials: IS
authors.lastname: Han
authors.forename: Bo Kyoung
authors.initials: BK
authors.lastname: Kim
keywords: Axonal neuropathy; Idiopathic CD4-positive T-lymphocytopenia