title: C-acylation of cyclopropanols: preparation of functionalized 1,4-diketones.
abstract: A convenient method for preparing attractively functionalized 1,4-diketones has been devised by palladium-catalyzed cross-coupling of cyclopropanols and acyl chlorides. The utility of this method has been demonstrated in an enantioselective synthesis of (+)-myrmicarin 217.
authors.affiliation: Department of Chemistry, Wayne State University, 5101 Cass Avenue, Detroit, Michigan 48202, United States.
authors.forename: Bibhuti Bhusan
authors.initials: BB
authors.lastname: Parida
authors.forename: Pragna Pratic
authors.initials: PP
authors.lastname: Das
authors.forename: Mathilde
authors.initials: M
authors.lastname: Niocel
authors.forename: Jin Kun
authors.initials: JK
authors.lastname: Cha
mesh_terms: D000215:Acylation; D002384:Catalysis; D004988:Ethers, Cyclic / Q000737:chemistry*; D006575:Heterocyclic Compounds, 3-Ring / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D004988:Ethers, Cyclic; D006575:Heterocyclic Compounds, 3-Ring; D007659:Ketones; C512230:myrmicarin; C043657:cyclopropanol; D010165:Palladium