title: Microbial transformations of 7-methoxyflavanone.
abstract: Microbial transformations of racemic 7-methoxyflavanone using strains of the genus Aspergillus (A. niger KB, A. ochraceus 456) and the strain Penicillium chermesinum 113 were described. The strain A. niger KB catalysed carbonyl group reduction, leading to (±)-2,4-cis-7-methoxyflavan-4-ol. Biotransformation with the help of A. ochraceus 456 gave two products: (+)-2,4-trans-7-methoxyflavan-4-ol and 4'-hydroxy-7-methoxyflavone. Transformation by means of P. chermesinum 113 resulted in a dihydrochalcone product, 4,2'-dihydroxy-4'-methoxydihydrochalcone. DPPH scavenging activity test proved that all the biotransformations products have higher antioxidant activity that the substrate.
authors.affiliation: Department of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, Wrocław 50-375, Poland. ekostrzew@gmail.com
authors.forename: Edyta
authors.initials: E
authors.lastname: Kostrzewa-Susłow
authors.forename: Tomasz
authors.initials: T
authors.lastname: Janeczko
mesh_terms: D001230:Aspergillus / Q000378:metabolism*; D001711:Biotransformation; D001713:Biphenyl Compounds / Q000494:pharmacology; D047309:Flavones / Q000378:metabolism*; D010407:Penicillium / Q000378:metabolism*; D010851:Picrates / Q000494:pharmacology
chemical_list: D001713:Biphenyl Compounds; D047309:Flavones; D010851:Picrates; C004931:1,1-diphenyl-2-picrylhydrazyl; C525137:7-methoxyflavone