title: Handheld miniature probe integrating diffuse optical tomography with photoacoustic imaging through a MEMS scanning mirror.
abstract: We describe a novel dual-modality imaging approach that integrates diffuse optical tomography (DOT) and photoacoustic imaging (PAI) through a miniaturized handheld probe based on microelectromechanical systems (MEMS) scanning mirror. We validate this dual-modal DOT/PAI approach using extensive phantom experiments, and demonstrate its application for tumor imaging using tumor-bearing mice systematically injected with targeted contrast agents.
authors.affiliation: Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA.
authors.forename: Hao
authors.initials: H
authors.lastname: Yang
authors.forename: Lei
authors.initials: L
authors.lastname: Xi
authors.forename: Sean
authors.initials: S
authors.lastname: Samuelson
authors.forename: Huikai
authors.initials: H
authors.lastname: Xie
authors.forename: Lily
authors.initials: L
authors.lastname: Yang
authors.forename: Huabei
authors.initials: H
authors.lastname: Jiang
keywords: (110.6960) Tomography; (170.0110) Imaging systems; (170.5120) Photoacoustic imaging