title: Amelanotic melanoma masquerading as a granular cell lesion.
abstract: Amelanotic melanoma (AM) presents a diagnostic challenge due to its wide clinical presentations, lack of pigmentation, and varied histological appearances. Immunohistochemistry plays a crucial role in the diagnosis of these lesions. Amelanotic melanoma of oral mucosa is an uncommon lesion. We report a case of a 50-year-old male patient with a growth on the anterior mandibular gingiva of seven-month duration. In the present case, histologically, the tumour resembled a granular cell lesion, which has not been reported previously in AM. Diagnosis was possible by a sequential panel of immunohistochemical markers, of which finally vimentin, S100, HMB45, and Melan-A were positive. The tumor was surgically excised, and postsurgical radiotherapy was given.
authors.affiliation: Department of Oral and Maxillofacial Pathology, Government Dental College, Kozhikode, Kerala 673008, India.
authors.forename: Deepak
authors.initials: D
authors.lastname: Pandiar
authors.forename: Shaini
authors.initials: S
authors.lastname: Basheer
authors.forename: P M
authors.initials: PM
authors.lastname: Shameena
authors.forename: S
authors.initials: S
authors.lastname: Sudha
authors.forename: Lakshmi J
authors.initials: LJ
authors.lastname: Dhana