title: [Management of brain metastases for lung cancer patients].
abstract: Brain metastases from primary lung cancer represent 40% of all brain metastases. On the other hand, 10 to 80% of primary lung cancer patients will present with synchronous or metachronous brain metastases. Management of these patients is therefore a big challenge. The management will depend on the circumstances of diagnosis (symptomatic or not), the cancer history (synchronous or metachronous brain metastases), the histology and the number of lesions.
authors.affiliation: Aix-Marseille université, Assistance publique-Hôpitaux de Marseille, service d'oncologie multidisciplinaire et innovations thérapeutiques, Hôpital Nord, chemin des Bourrelly, 13915 Marseille Cedex 20, France. Fabrice.barlesi@ap-hm.fr
authors.forename: Fabrice
authors.initials: F
authors.lastname: Barlesi
authors.forename: Natalia
authors.initials: N
authors.lastname: Khobta
authors.forename: Agnès
authors.initials: A
authors.lastname: Tallet
authors.forename: Anthony
authors.initials: A
authors.lastname: Goncalves
authors.forename: David
authors.initials: D
authors.lastname: Azria
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Spano
authors.forename: Antoine F
authors.initials: AF
authors.lastname: Carpentier
authors.forename: Jean
authors.initials: J
authors.lastname: Régis
authors.forename: Philippe
authors.initials: P
authors.lastname: Metellus
mesh_terms: D058070:Asymptomatic Diseases / Q000628:therapy; D001932:Brain Neoplasms / Q000517:prevention & control / Q000556:secondary* / Q000628:therapy*; D002289:Carcinoma, Non-Small-Cell Lung / Q000517:prevention & control / Q000556:secondary* / Q000628:therapy*; D016371:Cranial Irradiation; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*
keywords: brain metastases; chemotherapy; lung cancer; neurosurgery; radiotherapy; stereotaxic radiosurgery; targeted therapy