title: HIV-1 vaccines: let's get physical.
abstract: Ferguson et al. (2013) use applied physics to quantitate the fitness of HIV-1 Gag based on sequence variability across the protein. This enables a new approach to vaccine design that focuses CD8+ T cell responses on fitness-constrained parts of Gag.
authors.affiliation: Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, UK.
authors.forename: Nilu
authors.initials: N
authors.lastname: Goonetilleke
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: McMichael