title: Multifunctional hybrid materials from poly(3-hydroxybutyrate), TiO2 nanoparticles, and chitosan oligomers by combining electrospinning/electrospraying and impregnation.
abstract: Several types of fibrous material containing poly(3-hydroxybutyrate) (PHB), nanosized TiO2 -anatase (nanoTiO2 ), and chitosan oligomers are prepared by combining the electrospinning, electrospraying, and impregnation techniques. Simultaneous electrospinning/electrospraying provides uniform distribution of electrosprayed nanoTiO2 along the PHB fibers and throughout the mat. Hybrid materials of different design manifest excellent photocatalytic activity, even after repeated use. They exhibit high bactericidal activity against Escherichia coli. In addition, the fibrous scaffolds are compatible with human mesenchymal stem cells and provide a favorable environment for their development.
authors.affiliation: Laboratory of Bioactive Polymers, Institute of Polymers, Bulgarian Academy of Sciences, Acad. G. Bonchev St, Bl. 103A, BG-1113 Sofia, Bulgaria.
authors.forename: Elena
authors.initials: E
authors.lastname: Korina
authors.forename: Olya
authors.initials: O
authors.lastname: Stoilova
authors.forename: Nevena
authors.initials: N
authors.lastname: Manolova
authors.forename: Iliya
authors.initials: I
authors.lastname: Rashkov
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001672:Biocompatible Materials / Q000494:pharmacology*; D002384:Catalysis / Q000528:radiation effects; D002470:Cell Survival / Q000187:drug effects; D048271:Chitosan / Q000737:chemistry / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D006885:Hydroxybutyrates; D008027:Light; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000187:drug effects / Q000648:ultrastructure; D008751:Methylene Blue / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D011091:Polyesters; D000091402:Prohibitins; D059027:Recycling; D013499:Surface Properties; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds; D014025:Titanium / Q000494:pharmacology*; D000094122:Polyhydroxybutyrates
chemical_list: D000900:Anti-Bacterial Agents; D001672:Biocompatible Materials; D048271:Chitosan; D006885:Hydroxybutyrates; D008751:Methylene Blue; D011091:Polyesters; D000091402:Prohibitins; D014025:Titanium; C000717328:PHB protein, human; C009495:titanium dioxide; C003182:poly-beta-hydroxybutyrate; D000094122:Polyhydroxybutyrates