title: [Interest of systematic syphilis serology testing prior to assisted reproductive technology cycles: a retrospective study in Nantes, France].
abstract: BACKGROUND
  Syphilis has recently re-emerged in young adults. However, serological testing of patients undergoing assisted reproductive technology (ART) cycles and/or semen cryopreservation is not mandatory in every country.
  
  
  METHODS
  We conducted a retrospective analysis on our local database to evaluate the prevalence of syphilis among infertile couples, and discuss the interest of systematic syphilis serology testing in these patients.
  
  
  RESULTS
  Between 2000 and 2010, only one patient out of 4314 was diagnosed with chronic syphilis.
  
  
  CONCLUSIONS
  This study illustrates that systematic serological screening for syphilis in couples referred for semen cryopreservation or ART only allows exceptionally rare diagnosis. The cost-effectiveness of this strategy should be reconsidered.
authors.affiliation: Biologie et médecine du développement et de la reproduction, biologie de la reproduction, hôpital de l'Archet 2, BP 3079, 06202 Nice cedex 03, France. lattes.s@chu-nice.fr
authors.forename: S
authors.initials: S
authors.lastname: Lattes
authors.forename: T
authors.initials: T
authors.lastname: Freour
authors.forename: S
authors.initials: S
authors.lastname: Mirallie
authors.forename: A
authors.initials: A
authors.lastname: Guillouzouic
authors.forename: S
authors.initials: S
authors.lastname: Corvec
authors.forename: M E
authors.initials: ME
authors.lastname: Juvin
authors.forename: P
authors.initials: P
authors.lastname: Barriere
mesh_terms: D000328:Adult; D005260:Female; D005602:France / Q000453:epidemiology; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D007246:Infertility / Q000150:complications / Q000453:epidemiology / Q000628:therapy; D008297:Male; D011237:Predictive Value of Tests; D015995:Prevalence; D027724:Reproductive Techniques, Assisted / Q000009:adverse effects / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012662:Semen Preservation / Q000706:statistics & numerical data; D013587:Syphilis / Q000150:complications / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission; D013588:Syphilis Serodiagnosis / Q000706:statistics & numerical data