title: Neutrophil extracellular traps: A new link to cancer-associated thrombosis and potential implications for tumor progression.
abstract: Cancers prime neutrophils to release extracellular DNA traps through the systemic release of granulocyte colony-stimulating factor (G-CSF). We recently showed that these circulating neutrophil extracellular traps (NETs) promote the establishment of a pro-thrombotic state. The role of NETs in cancer biology and tumor progression may prove much more than an unfortunate side effect of cancer.
authors.affiliation: Program in Cellular and Molecular Medicine; Boston Children's Hospital; Boston, MA USA ; Department of Pediatrics; Harvard Medical School; Boston, MA USA.
authors.forename: Mélanie
authors.initials: M
authors.lastname: Demers
authors.forename: Denisa D
authors.initials: DD
authors.lastname: Wagner
keywords: Cancer; NETs; metastasis; neutrophils; thrombosis; tumor progression