title: Keratin Expression in Mammary Paget's Disease in situ with Intraductal Invasion.
abstract: We performed immunohistochemical studies of epithelial keratins in intraductal carcinoma in situ (IDCIS) in mammary Paget's disease (MPD). K7, K8 and K18 were expressed in IDCIS in MPD. However, K19 was not expressed in IDCIS in MPD. Interestingly, K17 was expressed in some tumor cells in IDCIS. K17, a hyperproliferative keratin, may suggest ductal invasion and poor prognosis in MPD.
authors.affiliation: Department of Dermatology, Meiwa Hospital, Nishinomiya, Osaka, Japan.
authors.forename: Ichiro
authors.initials: I
authors.lastname: Kurokawa
authors.forename: Sayaka
authors.initials: S
authors.lastname: Furukawa
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kishimoto
authors.forename: Ayako
authors.initials: A
authors.lastname: Kakuno
authors.forename: Airo
authors.initials: A
authors.lastname: Tsubura
keywords: Intraductal carcinoma; Keratins; Mammary Paget's disease