title: The "Test Your Memory" test performs better than the MMSE in a population without known cognitive dysfunction.
abstract: OBJECTIVE
  To examine the relation of performance on the self-administered Test Your Memory test (TYM) and the Mini-Mental State Examination (MMSE) with a comprehensive neuropsychological assessment in a population sample including people with modest cognitive decrements.
  
  
  METHODS
  Eighty-six participants (aged 56-77 years), without known cognitive dysfunction, performed a neuropsychological assessment including MMSE, and were asked to fill out the TYM. The relation between both the TYM and the MMSE and a neuropsychological assessment was examined by means of correlation analyses, area under the ROC curves for discriminating between a "normal" and "modest decrements"(≥1SD below the sample mean) group, and Bland-Altman plots.
  
  
  RESULTS
  Correlation with the full neuropsychological assessment was significantly stronger for the TYM than the MMSE (r=0.78 versus r=0.55; Steiger's Z=2.66, p<0.01). The TYM showed an area under the ROC-curve of 0.88 (95% CI 0.80 to 0.97) for differentiating between "normal" and "modest decrements" compared with 0.71 (0.53 to 0.90) for the MMSE. Bland-Altman plots showed limits of agreement for the TYM of -1.10 to 1.10 and for the MMSE of -1.39 to 1.38.
  
  
  CONCLUSIONS
  The TYM showed good correlation with a neuropsychological assessment, performed better in discriminating between variations of cognition and showed more agreement with a neuropsychological assessment than the MMSE.
authors.affiliation: Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands. p.s.koekkoek-3@umcutrecht.nl
authors.forename: Paula S
authors.initials: PS
authors.lastname: Koekkoek
authors.forename: Guy E H M
authors.initials: GE
authors.lastname: Rutten
authors.forename: Esther
authors.initials: E
authors.lastname: van den Berg
authors.forename: Sanne
authors.initials: S
authors.lastname: van Sonsbeek
authors.forename: Kees J
authors.initials: KJ
authors.lastname: Gorter
authors.forename: L Jaap
authors.initials: LJ
authors.lastname: Kappelle
authors.forename: Geert Jan
authors.initials: GJ
authors.lastname: Biessels
mesh_terms: D000368:Aged; D001288:Attention; D001786:Blood Glucose; D016009:Chi-Square Distribution; D003072:Cognition Disorders / Q000175:diagnosis* / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D056344:Executive Function; D005215:Fasting / Q000097:blood; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D008569:Memory Disorders / Q000209:etiology; D008606:Mental Processes / Q000502:physiology; D008609:Mental Status Schedule; D008875:Middle Aged; D009483:Neuropsychological Tests; D012680:Sensitivity and Specificity
chemical_list: D001786:Blood Glucose