title: Syncope and polymorphic ventricular tachycardia in the setting of a febrile illness.
abstract: An asymptomatic woman with no clinical history consulted for pneumonia-induced fever; she then presented episodes of syncope due to polymorphic ventricular tachycardia and ECG alterations compatible with Brugada syndrome. Genetic studies showed no alterations in the SCN5A gene but other polymorphisms were observed. Further genetic studies are required to elucidate the pathophysiological mechanisms of fever and the function of sodium channels.
authors.affiliation: Hospital Universitario Son Espases. Unidad Coronaria. Palma de Mallorca, España.
authors.forename: Marta
authors.initials: M
authors.lastname: Noris
authors.forename: Andrés
authors.initials: A
authors.lastname: Carrillo
authors.forename: Oscar
authors.initials: O
authors.lastname: Campuzano
authors.forename: Anna
authors.initials: A
authors.lastname: Santaella
authors.forename: Ramón
authors.initials: R
authors.lastname: Brugada
authors.forename: Javier
authors.initials: J
authors.lastname: García-Niebla
authors.forename: Miquel
authors.initials: M
authors.lastname: Fiol
mesh_terms: D003937:Diagnosis, Differential; D004562:Electrocardiography / Q000379:methods; D005260:Female; D005335:Fever of Unknown Origin / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D008875:Middle Aged; D013575:Syncope / Q000150:complications* / Q000175:diagnosis*; D017180:Tachycardia, Ventricular / Q000150:complications* / Q000175:diagnosis*
keywords: Fever-induced Brugada pattern; Polymorphic ventricular tachycardia