title: Draft Genome Sequence of Escherichia coli Strain ATCC 23506 (Serovar O10:K5:H4).
abstract: We report the 5.101-Mbp high-quality draft assembly of the Escherichia coli strain ATCC 23506 (serovar O10:K5:H4, also known as NCDC Bi 8337-41) genome. This uropathogenic strain, commonly referred to as E. coli K5, produces N-acetyl heparosan, a glycosaminoglycan-like capsular polysaccharide and precursor to the anticoagulant pharmaceutical heparin. Metabolic reconstruction of this genome will enable the prediction of gene deletions and overexpressions that lead to increased heparosan production.
authors.affiliation: Department of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA.
authors.forename: Brady F
authors.initials: BF
authors.lastname: Cress
authors.forename: Zachary R
authors.initials: ZR
authors.lastname: Greene
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Linhardt
authors.forename: Mattheos A G
authors.initials: MA
authors.lastname: Koffas