title: [Syphilis and pregnancy: study of 94 cases].
abstract: OBJECTIVE
  To study the epidemiology, diagnosis, treatment strategies and perinatal outcomes of gestational syphilis.
  
  
  METHODS
  We performed a retrospective study of 94 pregnant women with syphilis whose gestation and delivery were monitored in a Department of Obstetrics from 2002 to 2010 among a total of 85,806 births of women without syphilis in the same period.
  
  
  RESULTS
  The prevalence of gestational syphilis was 0.11%. Most of the women were foreign and the most prevalent type was late latent syphilis. Only 57 patients underwent right treatment despite adequate prescription. Maternal complications were confirmed in 31 pregnant women and 16 cases had fetal complications. We diagnosed 4 cases of neonatal syphilis, 3 of them with syphilitic meningitis, whose mothers had not completed the treatment correctly.
  
  
  CONCLUSIONS
  The implementation of a mandatory syphilis serology in the pregnancy has enabled us to diagnose many cases of late latent syphilis. The successful completion of treatment must be ensured to prevent vertical transmission.
authors.affiliation: Servicio de Obstetricia y Ginecología, Hospital Universitario La Paz, Madrid, España. mdelacalle55@hotmail.com
authors.forename: María
authors.initials: M
authors.lastname: de la Calle
authors.forename: Mireia
authors.initials: M
authors.lastname: Cruceyra
authors.forename: Mar
authors.initials: M
authors.lastname: de Haro
authors.forename: Fernando
authors.initials: F
authors.lastname: Magdaleno
authors.forename: María Dolores
authors.initials: MD
authors.lastname: Montero
authors.forename: Javier
authors.initials: J
authors.lastname: Aracil
authors.forename: Antonio
authors.initials: A
authors.lastname: González
mesh_terms: D000022:Abortion, Spontaneous / Q000209:etiology; D000293:Adolescent; D000328:Adult; D000349:Africa / Q000208:ethnology; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001208:Asia / Q000208:ethnology; D054242:Emigrants and Immigrants / Q000706:statistics & numerical data; D005061:Europe, Eastern / Q000208:ethnology; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology; D006801:Humans; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D008875:Middle Aged; D009494:Neurosyphilis / Q000209:etiology / Q000517:prevention & control; D007752:Obstetric Labor, Premature / Q000209:etiology; D010401:Penicillin G Benzathine / Q000627:therapeutic use; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D011256:Pregnancy Outcome; D015995:Prevalence; D012189:Retrospective Studies; D013020:South America / Q000208:ethnology; D013030:Spain / Q000453:epidemiology; D013587:Syphilis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000635:transmission; D013588:Syphilis Serodiagnosis; D013590:Syphilis, Congenital / Q000517:prevention & control*; D013592:Syphilis, Latent / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D010401:Penicillin G Benzathine
keywords: Congenital syphilis; Embarazo; Maternal syphilis; Pregnancy; Syphilis; Sífilis; Sífilis congénita; Sífilis materna