title: Swallowable Obalon® gastric balloons as an aid for weight loss: a pilot feasibility study.
abstract: The goal of this study was to evaluate the safety and the impact on weight loss of a new swallowable gastric balloon. In this prospective pilot study, 17 overweight or obese patients were included. Up to three balloons were ingested under fluoroscopic control. All balloons were removed by upper GI endoscopy, 12 weeks after the ingestion of the first balloon. 43 out of 44 attempts (98 %) to swallow a balloon were successful. Nausea and stomach pain were the most frequent side effects. Endoscopic procedures for balloon removal were uneventful. Weight loss was significant at weeks 4, 8, and 12. This pilot study showed no significant side effects induced by up to three balloons, and a significant weight loss.
authors.affiliation: Department of Digestive Diseases, Hospices Civils de Lyon, Hôpital E. Herriot, Lyon, France. francois.mion@chu-lyon.fr
authors.forename: François
authors.initials: F
authors.lastname: Mion
authors.forename: Mostafa
authors.initials: M
authors.lastname: Ibrahim
authors.forename: Sophie
authors.initials: S
authors.lastname: Marjoux
authors.forename: Thierry
authors.initials: T
authors.lastname: Ponchon
authors.forename: Sonia
authors.initials: S
authors.lastname: Dugardeyn
authors.forename: Sabine
authors.initials: S
authors.lastname: Roman
authors.forename: Jacques
authors.initials: J
authors.lastname: Deviere
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000284:Administration, Oral; D000328:Adult; D015992:Body Mass Index; D003679:Deglutition; D020878:Device Removal; D005240:Feasibility Studies; D005260:Female; D015905:Gastric Balloon / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009325:Nausea / Q000209:etiology; D009767:Obesity, Morbid / Q000628:therapy*; D010865:Pilot Projects; D011446:Prospective Studies; D016896:Treatment Outcome; D015431:Weight Loss