title: Expanding SUMO and ubiquitin-mediated signaling through hybrid SUMO-ubiquitin chains and their receptors.
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Guzzo
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Matunis
mesh_terms: D000818:Animals; D000067699:Ataxin-3; D002352:Carrier Proteins / Q000737:chemistry / Q000378:metabolism; D004260:DNA Repair; D004268:DNA-Binding Proteins; D056827:Endosomal Sorting Complexes Required for Transport / Q000737:chemistry / Q000378:metabolism; D056488:Histone Chaperones; D006801:Humans; D009419:Nerve Tissue Proteins / Q000737:chemistry / Q000378:metabolism; D009687:Nuclear Proteins / Q000737:chemistry / Q000378:metabolism; D046988:Proteasome Endopeptidase Complex / Q000737:chemistry / Q000378:metabolism; D054730:Protein Interaction Domains and Motifs; D016601:RNA-Binding Proteins; D012097:Repressor Proteins / Q000737:chemistry / Q000378:metabolism; D015398:Signal Transduction; D025841:Small Ubiquitin-Related Modifier Proteins / Q000737:chemistry / Q000378:metabolism*; D025801:Ubiquitin / Q000737:chemistry / Q000378:metabolism*; D043222:Ubiquitin Thiolesterase / Q000737:chemistry / Q000378:metabolism
chemical_list: D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D056827:Endosomal Sorting Complexes Required for Transport; D056488:Histone Chaperones; D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins; C498506:PSMD4 protein, human; D016601:RNA-Binding Proteins; D012097:Repressor Proteins; C486696:STAMBP protein, human; D025841:Small Ubiquitin-Related Modifier Proteins; C466234:UIMC1 protein, human; C404488:USP25 protein, human; D025801:Ubiquitin; C092341:ATXN3 protein, human; D000067699:Ataxin-3; D043222:Ubiquitin Thiolesterase; D046988:Proteasome Endopeptidase Complex
keywords: DNA repair; Hybrid chains; SUMO; Ubiquitin; post-translational modification; proteolysis