title: In vivo effect of oat cereal β-glucan on metabolic indexes and satiety-related hormones in diet-induced obesity C57-Bl mice.
abstract: This study explored the dose-dependent effect of oat cereal β-glucan on improving metabolic indexes of obesity mice. C57-Bl mice were randomized to chow diet (N) group and high fat diet group and other three doses of oat β-glucan groups (low β-glucan, medium β-glucan, and high β-glucan). Energy intake, glucose, lipids, and appetite related hormones were tested. Dose-dependent relation was observed on oat β-glucan doses and body weight change, average energy intake, total cholesterol, HDL cholesterol, plasma neural peptide Y, arcuate neural peptide Y mRNA, and arcuate neural peptide Y receptor 2 mRNA level. Oat β-glucan helped to increase plasma peptide Y-Y and intestine peptide Y-Y expression in obesity mice.
authors.affiliation: Department of General Surgery, Chengdu Military General Hospital, Chengdu, PR China. helenmedic@gmail.com
authors.forename: Ning
authors.initials: N
authors.lastname: Lin
authors.forename: Yunming
authors.initials: Y
authors.lastname: Li
authors.forename: Lijun
authors.initials: L
authors.lastname: Tang
authors.forename: Jiaojiao
authors.initials: J
authors.lastname: Shi
authors.forename: Yi
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000818:Animals; D018554:Avena / Q000737:chemistry*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004032:Diet; D002149:Energy Intake; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008820:Mice, Obese; D009765:Obesity / Q000097:blood*; D019894:Peptide YY / Q000097:blood / Q000235:genetics; D012527:Satiation / Q000187:drug effects*; D047071:beta-Glucans / Q000008:administration & dosage*
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D047071:beta-Glucans; D019894:Peptide YY
keywords: Diet-induced obesity; GLP-1; NPY; PYY3-36; β-Glucan