title: Mitochondrial disease: a challenge for the caregiver, the family, and society.
abstract: Mitochondrial diseases represent a genetically and clinically heterogeneous group of inherited metabolic disorders, often resulting in poor functional and survival outcomes for the patient and considerable psychosocial distress for the caregiver. The systematic review undertaken in the present paper emphasizes the critical role of the caregiver in the management of a child with mitochondrial disease, with focus on the burden of mitochondrial disease on the caregiver, the family, and society.
authors.affiliation: Department of Pediatrics, University of Gothenburg, The Queen Silvia's Children Hospital, Gothenburg, Sweden. kalliopi.sofou@vgregion.se
authors.forename: Kalliopi
authors.initials: K
authors.lastname: Sofou
mesh_terms: D000203:Activities of Daily Living / Q000145:classification* / Q000523:psychology*; D001008:Anxiety Disorders / Q000175:diagnosis / Q000235:genetics / Q000523:psychology; D017028:Caregivers / Q000523:psychology*; D002648:Child; D017281:Cost of Illness; D003866:Depressive Disorder / Q000175:diagnosis / Q000235:genetics / Q000523:psychology; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D028361:Mitochondrial Diseases / Q000235:genetics / Q000523:psychology* / Q000628:therapy*; D009035:Mothers / Q000523:psychology; D010555:Personality Inventory; D011788:Quality of Life / Q000523:psychology*; D012944:Social Support; D013315:Stress, Psychological / Q000150:complications