title: Shared G12 VP7 gene among human and bovine rotaviruses detected in Cameroonian villages.
abstract: Group A rotaviruses (RVA) are an important enteric pathogen in humans and livestock animals. Transmission of animal RVA strains to humans has been documented on several occasions. A reverse route of transmission of RVA under natural circumstances is anticipated, although evidence is scarce. However, experimental studies indicated that animals can be infected with human RVAs. By screening the stool samples collected from 157 cattle during 2011 in two Cameroonian villages, four samples (2.5%) were found positive for RVA. Upon sequence analysis of a 410 bp fragment of the VP7 gene, the RVA strains shared up to 100% nt identity to each other and to G12 RVAs identified in human patients living in the same geographic regions. This finding provides evidence for a human-to-animal transmission of an epidemic human rotavirus strain.
authors.affiliation: Faculty of Medicine and Biomedical Sciences, University of Yaoundé, Yaoundé, Cameroon.
authors.forename: Valentine Ngum
authors.initials: VN
authors.lastname: Ndze
authors.forename: Eric Akum
authors.initials: EA
authors.lastname: Achidi
authors.forename: Hajnalka
authors.initials: H
authors.lastname: Papp
authors.forename: Eszter
authors.initials: E
authors.lastname: Kovács
authors.forename: Szilvia
authors.initials: S
authors.lastname: Farkas
authors.forename: Dieudonne
authors.initials: D
authors.lastname: Adiogo
authors.forename: Péter
authors.initials: P
authors.lastname: Kisfali
authors.forename: Marxcel Bong
authors.initials: MB
authors.lastname: Ngeng
authors.forename: Marie Therese Obama
authors.initials: MT
authors.lastname: Abena
authors.forename: Vito
authors.initials: V
authors.lastname: Martella
authors.forename: Mathew Dioh
authors.initials: MD
authors.lastname: Esona
authors.forename: Krisztián
authors.initials: K
authors.lastname: Bányai
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000235:genetics*; D002163:Cameroon; D036022:Capsid Proteins / Q000235:genetics*; D002417:Cattle; D019143:Evolution, Molecular; D006801:Humans; D010865:Pilot Projects; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012401:Rotavirus / Q000235:genetics*; D012400:Rotavirus Infections / Q000635:transmission
chemical_list: D000956:Antigens, Viral; D036022:Capsid Proteins; C050779:VP7 protein, Rotavirus