title: Endometriosis - clinical approach based on histological findings.
abstract: Endometriosis is a benign disease defined by the presence of endometrial glands and stroma outside of the uterus and is associated with both pelvic pain and infertility. The most common sites of endometriosis, in decreasing order of frequency, are the ovaries, anterior and posterior cul-de-sac, posterior broad ligaments, uterosacral ligaments, uterus, fallopian tubes, sigmoid colon, appendix, and round ligaments. The main treatment is surgical, but often-microscopic islands of endometrial tissue remain, which proliferate and are responsible for relapses. We tested the efficacy of two drugs (Medroxyprogesterone and Triptorelinum), administered for six months to prevent recurrence after surgery. Treatment with Medroxyprogesterone was 100% effective in terms of relapse, while Triptorelinum could not prevent recurrence of endometriosis.
authors.affiliation: “Prof. Dr. Panait Sârbu” Clinical Hospital of Obstetrics and Gynecology, Bucharest, Romania.
authors.forename: C
authors.initials: C
authors.lastname: Cristescu
authors.forename: Andreea
authors.initials: A
authors.lastname: Velişcu
authors.forename: B
authors.initials: B
authors.lastname: Marinescu
authors.forename: Anca
authors.initials: A
authors.lastname: Pătraşcu
authors.forename: E T
authors.initials: ET
authors.lastname: Traşcă
authors.forename: O T
authors.initials: OT
authors.lastname: Pop
mesh_terms: D000293:Adolescent; D000328:Adult; D004715:Endometriosis / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D055815:Young Adult