title: Chitin, chitosan, and glycated chitosan regulate immune responses: the novel adjuvants for cancer vaccine.
abstract: With the development of cancer immunotherapy, cancer vaccine has become a novel modality for cancer treatment, and the important role of adjuvant has been realized recently. Chitin, chitosan, and their derivatives have shown their advantages as adjuvants for cancer vaccine. In this paper, the adjuvant properties of chitin and chitosan were discussed, and some detailed information about glycated chitosan and chitosan nanoparticles was also presented to illustrate the trend for future development.
authors.affiliation: Department of Oncology, The First Affiliated Hospital of Chinese PLA General Hospital, Beijing 100048, China.
authors.forename: Xiaosong
authors.initials: X
authors.lastname: Li
authors.forename: Min
authors.initials: M
authors.lastname: Min
authors.forename: Nan
authors.initials: N
authors.lastname: Du
authors.forename: Ying
authors.initials: Y
authors.lastname: Gu
authors.forename: Tomas
authors.initials: T
authors.lastname: Hode
authors.forename: Mark
authors.initials: M
authors.lastname: Naylor
authors.forename: Dianjun
authors.initials: D
authors.lastname: Chen
authors.forename: Robert E
authors.initials: RE
authors.lastname: Nordquist
authors.forename: Wei R
authors.initials: WR
authors.lastname: Chen
mesh_terms: D000276:Adjuvants, Immunologic; D000818:Animals; D019496:Cancer Vaccines / Q000276:immunology*; D002686:Chitin / Q000276:immunology*; D048271:Chitosan / Q000276:immunology*; D006801:Humans; D009369:Neoplasms / Q000628:therapy*
chemical_list: D000276:Adjuvants, Immunologic; D019496:Cancer Vaccines; C121252:glycated chitosan; D002686:Chitin; D048271:Chitosan