title: Nondestructive size determination of thiol-stabilized gold nanoclusters in solution by diffusion ordered NMR spectroscopy.
abstract: Diffusion ordered NMR spectroscopy (DOSY) was used as an analytical tool to estimate the size of thiol-stabilized gold nanoclusters in solution, namely, phenylethanethiol (PET) stabilized Au25(PET)18, Au38(PET)24, and Au144(PET)60. This was achieved by determining the diffusion coefficient and hydrodynamic radius from solution samples that were confirmed to be monodispersed by electrospray ionization mass spectrometry. The average cluster diameters obtained by this technique were estimated to be 1.7, 2.2, and 3.1 nm for the Au25(PET)18, Au38(PET)24, and Au144(PET)60 nanoclusters, respectively, which were shown to agree well with the average diameters of the corresponding single crystal or theoretical structures reported in the literature. Consequently, the DOSY technique is demonstrated to be a potentially valuable nondestructive tool for characterization of nanoparticle mixtures and verifying the purity of product solutions.
authors.forename: Kirsi
authors.initials: K
authors.lastname: Salorinne
authors.forename: Tanja
authors.initials: T
authors.lastname: Lahtinen
authors.forename: Jaakko
authors.initials: J
authors.lastname: Koivisto
authors.forename: Elina
authors.initials: E
authors.lastname: Kalenius
authors.forename: Maija
authors.initials: M
authors.lastname: Nissinen
authors.forename: Mika
authors.initials: M
authors.lastname: Pettersson
authors.forename: Hannu
authors.initials: H
authors.lastname: Häkkinen
mesh_terms: D004058:Diffusion; D006046:Gold / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008958:Models, Molecular; D049329:Nanostructures / Q000737:chemistry*; D010316:Particle Size; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D013438:Sulfhydryl Compounds; D006046:Gold