title: [Regulation of MGMT and application for the therapy to attenuate the chemoresistance].
authors.affiliation: Department of Cancer Pathology, Hokkaido University Graduate School of Medicine.
authors.forename: Shinji
authors.initials: S
authors.lastname: Kohsaka
authors.forename: Hiromi
authors.initials: H
authors.lastname: Kanno
authors.forename: Shinya
authors.initials: S
authors.lastname: Tanaka
mesh_terms: D018906:Antineoplastic Agents, Alkylating / Q000494:pharmacology / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy*; D015254:DNA Modification Methylases / Q000032:analysis / Q000502:physiology*; D045643:DNA Repair Enzymes / Q000032:analysis / Q000502:physiology*; D003606:Dacarbazine / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D019008:Drug Resistance, Neoplasm; D005910:Glioma / Q000188:drug therapy*; D006801:Humans; D000077204:Temozolomide; D025521:Tumor Suppressor Proteins / Q000032:analysis / Q000502:physiology*
chemical_list: D018906:Antineoplastic Agents, Alkylating; D025521:Tumor Suppressor Proteins; D003606:Dacarbazine; D015254:DNA Modification Methylases; C515491:MGMT protein, human; D045643:DNA Repair Enzymes; D000077204:Temozolomide