title: A silver(I)-catalyzed tandem reaction of 2-alkynylbenzaldoximes with ketenes.
abstract: A novel and unexpected reaction of 2-alkynylbenzaldoximes with ketenes in the presence of silver triflate (10 mol%) under mild conditions is discovered. This reaction proceeds through 6-endo-cyclization, [3 + 2] cycloaddition, and rearrangement, leading to isoquinoline derivatives in moderate to good yields.
authors.affiliation: Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science & Technology Normal University, Nanchang 330013, China.
authors.forename: Hongliang
authors.initials: H
authors.lastname: Liu
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
authors.forename: Shouzhi
authors.initials: S
authors.lastname: Pu
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Wang
mesh_terms: D002384:Catalysis; D003500:Cyclization; D005030:Ethylenes / Q000737:chemistry*; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000737:chemistry; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010091:Oximes / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*
chemical_list: D005030:Ethylenes; D007546:Isoquinolines; D007659:Ketones; D009942:Organometallic Compounds; D010091:Oximes; D012834:Silver; C039109:isoquinoline; C008223:ketene