title: [Optimization of conditions of Pseudomonas aeruginosa bacteriocin induction].
abstract: Influence of cultivation conditions on activity of bacteriocins produced by Pseudomonas aeruginosa YKM B-333 has been investigated. It was shown, that the induction of bacteriocins with maximum activity values occurs on LB medium at 28 degrees C after addition of 100 microg/ml of nalidixic acid in a late logarithmic growth phase. Using the proposed methods for induction optimization permits to improve activity of P. aeruginosa YKM B-333 bacteriocins 256 times and to reach the index of 6.5 million AU/ml.
authors.forename: A B
authors.initials: AB
authors.lastname: Balko
authors.forename: V V
authors.initials: VV
authors.lastname: Vidasov
authors.forename: L V
authors.initials: LV
authors.lastname: Avdeeva
mesh_terms: D001430:Bacteriocins / Q000096:biosynthesis*; D003470:Culture Media; D004305:Dose-Response Relationship, Drug; D009268:Nalidixic Acid / Q000494:pharmacology; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000378:metabolism; D013696:Temperature
chemical_list: D001430:Bacteriocins; D003470:Culture Media; D009268:Nalidixic Acid