title: Hemicrania continua responsive to botulinum toxin type a: a case report.
abstract: BACKGROUND
  Hemicrania continua (HC) is a primary headache disorder with full response to indomethacin as one of its diagnostic criteria; however, indomethacin's side effects could limit its use in HC.
  
  
  METHODS
  We report a 33-year-old lady whose headache fulfilled the criteria for HC, but the patient developed gastric side effect to indomethacin and did not respond to other pharmacological treatments; however, injecting botulinum toxin type A has led to complete resolution of all of her symptoms.
  
  
  CONCLUSIONS
  We hypothesize the mechanism by which botulinum toxin type A has led to our results through reviewing recent functional neuroimaging findings used to understand the pathophysiology of different primary headache disorders.
authors.affiliation: Department of Neurology, Hull Royal Infirmary, Kingston-upon-Hull, UK.
authors.forename: Modar
authors.initials: M
authors.lastname: Khalil
authors.forename: Fayyaz
authors.initials: F
authors.lastname: Ahmed
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D005260:Female; D005756:Gastritis / Q000139:chemically induced; D006261:Headache / Q000188:drug therapy*; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects; D009465:Neuromuscular Agents / Q000627:therapeutic use*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A; D007213:Indomethacin