title: Resolution of acute photoreceptor damage as revealed by serial SD-OCT.
abstract: OBJECTIVE
  To describe findings in spectral-domain optical coherence tomography (SD-OCT) for four patients with acute foveal photoreceptor damage.
  
  
  METHODS
  Four patients with acute foveal photoreceptor damage were evaluated by color photography and SD-OCT during follow-up. All four cases were Japanese patients with high myopia. Three were women aged 28, 29, and 46 years and one was a boy aged 17 years. The follow-up ranged from 2 weeks to 3 months. On presentation, four eyes had orange-yellow foveal granularity with visual acuities that varied from 1.2 to 0.5. Spectral-domain optical coherence tomography revealed a disrupted photoreceptor layer. All patients achieved spontaneous resolution without treatment within a few months. Of the four eyes, only one had recurrence of the disease.
  
  
  CONCLUSIONS
  Lesions exhibiting orange-yellow foveal granularity characteristic of these four cases corresponded to hyperreflective localized photoreceptor lesions on SD-OCT. Spectral-domain optical coherence tomography was useful for detecting an acute disruption and a resolution of the photoreceptor layer in the fovea.
authors.affiliation: Department of Ophthalmology, Jikei University School of Medicine, Tokyo, Japan. tstmski@jikei.ac.jp
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Sakai
authors.forename: Mayumi
authors.initials: M
authors.lastname: Inaba
authors.forename: Kenichi
authors.initials: K
authors.lastname: Kohzaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsuneoka
mesh_terms: D000293:Adolescent; D000328:Adult; D018450:Disease Progression; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005584:Fovea Centralis / Q000473:pathology*; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000473:pathology* / Q000503:physiopathology; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity; D055815:Young Adult