title: Musicogenic seizures in Dravet syndrome.
abstract: Dravet syndrome is an epileptic encephalopathy characterized by multiple types of seizures. We report the first case of musicogenic reflex seizures in a 7-year-old male with a mutation in the SCN1A gene causing Dravet syndrome. Reflex seizures have been reported in patients with Dravet syndrome provoked by body temperature elevation, looking at visual patterns, or under intermittent photic stimulation. The case we report widens the spectrum of reflex seizures recorded in patients with Dravet syndrome. Cortical hyperexcitability of genetic origin could explain the tendency of these patients to experience reflex seizures.
authors.affiliation: Paediatric Neurology Unit, Clínica Universidad de Navarra, Pamplona, Spain.
authors.forename: Rocio
authors.initials: R
authors.lastname: Sanchez-Carpintero
authors.forename: Ana
authors.initials: A
authors.lastname: Patiño-Garcia
authors.forename: Elena
authors.initials: E
authors.lastname: Urrestarazu
mesh_terms: D002648:Child; D004831:Epilepsies, Myoclonic / Q000150:complications / Q000235:genetics / Q000503:physiopathology*; D006801:Humans; D008297:Male; D009146:Music; D009154:Mutation / Q000235:genetics; D062550:NAV1.1 Voltage-Gated Sodium Channel / Q000235:genetics; D012018:Reflex / Q000235:genetics; D012640:Seizures / Q000209:etiology / Q000235:genetics / Q000503:physiopathology*
chemical_list: D062550:NAV1.1 Voltage-Gated Sodium Channel; C568242:SCN1A protein, human