title: [Squamous cell carcinoma of the lip: a report of 30 cases].
abstract: BACKGROUND
  Squamous cell carcinoma (SCC) is one of the most common malignant tumors of the lips (90%). The prognosis of these SCC seems to be poor thus here periorificial localization.
  
  
  OBJECTIVE
  To present the epidemiological, clinical, pathological, therapeutic features and out come of SCC of the lips.
  
  
  METHODS
  we conducted a retrospective study performed in the dermatology department of the La Rabta hospital of Tunis over a 11-year-period [2000-2010] recording patients with histologically confirmed SCC of lips.
  
  
  RESULTS
  Thirty patients were included (26 men and 4 women) with an average age of 63 years. The most frequent risk factors were smoking and chronic sunlight exposure. The occurrence of the labial SCC on a precursor lesion was noted in 11 cases. It occurred more frequently on the lower lip (80%). Tumor was ulcero-vegetant in 21 patients. Twenty patients had a commune SCC, 19 of them were well-differentiated. Surgery was indicated in 18 cases and 10 patients were treated by exclusive radiotherapy. Lymph nodes metastases were noted in 2 cases. No visceral metastasis was observed. During the period of follow-up (20.12 months), two patients died.
  
  
  CONCLUSIONS
  The diagnosis of SCC of the lips is late and the treatment often mutilating. The improvement of the prognosis depends not only on the early diagnosis and the treatment of the precursors, but also on the photo protection and alcohol and smoking eviction.
authors.affiliation: Universite Tunis, El Manar, Tunisie.
authors.forename: Ines
authors.initials: I
authors.lastname: Zaraa
authors.forename: S
authors.initials: S
authors.lastname: Ben Taazayet
authors.forename: I
authors.initials: I
authors.lastname: Dakhli
authors.forename: I
authors.initials: I
authors.lastname: Chelly
authors.forename: Mourad
authors.initials: M
authors.lastname: Mokni
authors.forename: Moncef
authors.initials: M
authors.lastname: Zitouna
authors.forename: Amel
authors.initials: A
authors.lastname: Ben Osman
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D008048:Lip Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors