title: Carbapenem resistant Enterobacteriaceae carrying New Delhi metallo-β-lactamase gene (NDM-1) in Taiwan.
abstract: The spread of New Delhi metallo-β-lactamase gene (NDM-1)-producing bacteria has become a growing concern to the medical community worldwide. In this study, we reported 4 NDM-1-positive Enterobacteriaceae isolates recovered from two Taiwanese patients having travel history. The β-lactamase genetic background, antimicrobial susceptibility, clonal relationships, and plasmid sizes of the NDM-1-producing Enterobacteriaceae were investigated. This report highlights the alarming introduction of NDM-1 gene among Enterobacteriaceae in Taiwan.
authors.affiliation: Bacterial Enteric and Emerging Diseases Laboratory, Research and Diagnostic Center, Centers for Disease Control, Taipei, Taiwan.
authors.forename: Shiow-Jen
authors.initials: SJ
authors.lastname: Wang
authors.forename: Shih-Hui
authors.initials: SH
authors.lastname: Chiu
authors.forename: Ying-Chun
authors.initials: YC
authors.lastname: Lin
authors.forename: Yun-Chi
authors.initials: YC
authors.lastname: Tsai
authors.forename: Jung-Jung
authors.initials: JJ
authors.lastname: Mu
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015780:Carbapenems / Q000494:pharmacology*; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D004755:Enterobacteriaceae / Q000187:drug effects* / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008826:Microbial Sensitivity Tests; D010957:Plasmids; D013624:Taiwan; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D015780:Carbapenems; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1