title: Bilateral Candida endophthalmitis in a premature infant.
abstract: Endogenous infantile Candida endophthalmitis is a rare but potentially devastating condition resulting from sequestration of the fungus within the lens after systemic infection. We report the case of a 20-week-old girl with a history of Candida sepsis who presented with bilateral Candida albicans endophthalmitis 15 weeks after completing a 6-week course of intravenous antifungal therapy. Prompt vitrectomy resulted in salvage of the right eye, although a total retinal detachment occurred. Cataract extraction and administration of intravenous and intravitreal amphotericin B preserved vision in the left eye.
authors.affiliation: Department of Ophthalmology, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina 27157, USA.
authors.forename: Rebecca A
authors.initials: RA
authors.lastname: Manning
authors.forename: Joshua N
authors.initials: JN
authors.lastname: Carlson
authors.forename: Eric W
authors.initials: EW
authors.lastname: Hein
authors.forename: R Grey
authors.initials: RG
authors.lastname: Weaver
authors.forename: Craig M
authors.initials: CM
authors.lastname: Greven
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D002176:Candida albicans / Q000302:isolation & purification*; D058387:Candidemia / Q000150:complications*; D002387:Cataract Extraction; D009877:Endophthalmitis / Q000382:microbiology*; D015821:Eye Infections, Fungal / Q000382:microbiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature
chemical_list: D000935:Antifungal Agents