title: Tumor dissemination: an EMT affair.
abstract: A recent paper reports that circulating tumor cells (CTCs) from metastatic breast cancer patients exhibit heterogeneous epithelial and mesenchymal phenotypes and that CTCs display higher frequencies of partial or full-blown mesenchymal phenotype than carcinoma cells within primary tumors. Mesenchymal-like CTCs are also elevated in patients who are refractory to therapy.
authors.affiliation: Department of Biochemistry, National University of Singapore, Singapore 117599. jpthiery@imcb.a-star.edu.sg
authors.forename: Jean Paul
authors.initials: JP
authors.lastname: Thiery
authors.forename: Chwee Teck
authors.initials: CT
authors.lastname: Lim