title: Periodontal regeneration using platelet-derived growth factor in infrabony defects: a series of three cases.
abstract: The periodontal researchers and clinicians, in an effort to develop effective regenerative therapies, have sought to understand key events involved in the regeneration of periodontium. Polypeptide growth factors are a class of natural biological mediators which regulate key cellular events in tissue repair. Platelet-derived growth factor (PDGF) is the most thoroughly studied growth factor in periodontal regeneration. The present case series evaluate the effectiveness of platelet-derived growth factor (rh-PDGF-BB) in combination with beta-tricalcium phosphate ( β -TCP) to achieve periodontal regeneration in 3 infrabony defects.
authors.affiliation: Department of Periodontology and Implantology, Sharad Pawar Dental College and Hospital, Maharashtra, Wardha 442001, India.
authors.forename: Kaustubh
authors.initials: K
authors.lastname: Thakare
authors.forename: M L
authors.initials: ML
authors.lastname: Bhongade
authors.forename: Preeti
authors.initials: P
authors.lastname: Charde
authors.forename: Priyanka
authors.initials: P
authors.lastname: Jaiswal
authors.forename: Nachiket
authors.initials: N
authors.lastname: Shah
authors.forename: Aniruddha
authors.initials: A
authors.lastname: Deshpande