title: Metabolic syndrome and shift work: a systematic review.
abstract: The aim of this systematic review was to examine the association between shift work and metabolic syndrome (MetS) as well as the potential confounders investigated. A systematic search was conducted with the aim of finding original articles on the association between shift work and MetS. The included articles were chosen based on established inclusion criteria; their methodological quality was assessed using a validated quality checklist. A total of 10 articles were included in this review. The majority of the studies were classified as having a low risk of bias. The definitions of MetS and shift work varied between studies. Among the ten studies, eight found a positive association between shift work and MetS after controlling for socio-demographic and behavioral factors. Only three studies included sleep duration as a confounder, and these studies presented discordant results. We conclude that there was insufficient evidence regarding the association between shift work and prevalent MetS when the confounders are taken into account.
authors.affiliation: Post-graduate Programme in Endocrinology, Federal University of Rio Grande do Sul State, Brazil.
authors.forename: Raquel
authors.initials: R
authors.lastname: Canuto
authors.forename: Anderson S
authors.initials: AS
authors.lastname: Garcez
authors.forename: Maria T A
authors.initials: MT
authors.lastname: Olinto
mesh_terms: D006801:Humans; D024821:Metabolic Syndrome / Q000209:etiology*; D012307:Risk Factors; D020178:Sleep Disorders, Circadian Rhythm / Q000150:complications*; D014940:Work Schedule Tolerance / Q000502:physiology
keywords: HDL cholesterol; HR; IDF; International Diabetes Federation; MetS; Metabolic syndrome; NCEP ATP; National Cholesterol Education Program's Adult Treatment Panel; SES; Shift work; Sleep disorders; Systematic review; hazard ratio; high-density lipoprotein cholesterol; metabolic syndrome; socioeconomic status