title: Influence of etiologic factors on speech perception of cochlear-implanted children.
abstract: OBJECTIVE
  Rehabilitation success in cochlear implant patients is influenced by many factors. Influence of different etiologies of deafness on rehabilitation outcome is assessed.
  
  
  METHODS
  
  
  
  METHODS
  Retrospective survey of patients.
  
  
  METHODS
  University hospital. Secondary referral center.
  
  
  METHODS
  One hundred and sixty-three between 1996 and 2008 implanted children (0-18 years, mean 5.17 years).
  
  
  METHODS
  Evaluation of patients' data: origin of deafness, hearing and speech test results. Access Data Base; Wilcoxon and t-test.
  
  
  RESULTS
  Mean follow-up: 65.4 months. Etiology of deafness in children found in 104 cases: 69 (51.9%) suffered from hereditary hearing loss. All children showed improvement in their auditory performance, children with connexin-26 mutation performed significantly best, Usher and CHARGE-syndrome children significantly worst. Post-meningitic and post-septic children developed slower but reached same levels later.
  
  
  CONCLUSIONS
  Primary cause of deafness, among other factors, has a considerable impact on outcome of rehabilitation. This offers possibilities to influence the outcome by etiology-adjusted therapy modules.
authors.affiliation: Department of Otorhinolaryngology, University Hospital Essen, Essen, Germany. sanderera@web.de
authors.forename: Sandra
authors.initials: S
authors.lastname: Janeschik
authors.forename: Melanie
authors.initials: M
authors.lastname: Teschendorf
authors.forename: Heike
authors.initials: H
authors.lastname: Bagus
authors.forename: Diana
authors.initials: D
authors.lastname: Arweiler-Harbeck
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D019929:Cochlear Implantation / Q000009:adverse effects / Q000379:methods* / Q000534:rehabilitation; D003054:Cochlear Implants; D015331:Cohort Studies; D000013:Congenital Abnormalities / Q000175:diagnosis / Q000453:epidemiology; D000072259:Connexin 26; D017630:Connexins / Q000235:genetics; D003241:Consanguinity; D003638:Deafness / Q000151:congenital / Q000209:etiology* / Q000534:rehabilitation / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006319:Hearing Loss, Sensorineural / Q000151:congenital / Q000175:diagnosis / Q000534:rehabilitation / Q000601:surgery*; D006320:Hearing Tests; D006801:Humans; D007223:Infant; D008297:Male; D009154:Mutation; D012189:Retrospective Studies; D018570:Risk Assessment; D013065:Speech Intelligibility; D013067:Speech Perception / Q000502:physiology*; D018709:Statistics, Nonparametric; D013997:Time Factors; D016896:Treatment Outcome; D052245:Usher Syndromes / Q000175:diagnosis / Q000453:epidemiology
chemical_list: D017630:Connexins; D000072259:Connexin 26