title: Seroepidemiological study of chagas disease in the southern Amazon region of ecuador.
abstract: To determine the extent of Trypanosoma cruzi infection and/or transmission in the southern Amazon region of Ecuador, three indigenous communities in the provinces of Pastaza and Morona Santiago were serosurveyed. Chagatest(TM), Immunocomb(®)II and immunofluorescent (IF) assays were used. Among the 385 inhabitants examined, nine (2.34%) were seropositive for T. cruzi infection. Of the nine positive sera, four (44.4%) fall in the 10-19, one each in the 20-29, 30-39 and 40-49, and two in the 50-59 age groups. These results suggested the possible existence of an autochthonous active T. cruzi transmission in the region and provide the first serological evidence for T. cruzi infection in the southern province of Morona Santiago bordering Peru. Further studies are needed in these Amazonian provinces to ascertain the spread of T. cruzi infection in the area.
authors.affiliation: Laboratorio de Parasitologia Molecular y Medicina Tropical, Centro de Biomedicina, Facultad de Medicina, Universidad Central del Ecuador, Quito, Ecuador.
authors.forename: Angel G
authors.initials: AG
authors.lastname: Guevara
authors.forename: Richard D
authors.initials: RD
authors.lastname: Atherton
authors.forename: Michael A
authors.initials: MA
authors.lastname: Wauters
authors.forename: Yosselin
authors.initials: Y
authors.lastname: Vicuña
authors.forename: Marcos
authors.initials: M
authors.lastname: Nelson
authors.forename: Jose
authors.initials: J
authors.lastname: Prado
authors.forename: Hirotomo
authors.initials: H
authors.lastname: Kato
authors.forename: Manuel H
authors.initials: MH
authors.lastname: Calvopiña
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Hashiguchi
keywords: Amazon; Chagas disease; Ecuador; Trypanosoma cruzi; seroprevalence