title: Influence of CYP2C19*2 and *3 loss-of-function alleles on the pharmacodynamic effects of standard- and high-dose clopidogrel in East Asians undergoing percutaneous coronary intervention: the results of the ACCEL-DOUBLE-2N3 study.
authors.forename: Y-H
authors.initials: YH
authors.lastname: Jeong
authors.forename: K A
authors.initials: KA
authors.lastname: Abadilla
authors.forename: U S
authors.initials: US
authors.lastname: Tantry
authors.forename: Y
authors.initials: Y
authors.lastname: Park
authors.forename: J-S
authors.initials: JS
authors.lastname: Koh
authors.forename: C H
authors.initials: CH
authors.lastname: Kwak
authors.forename: J-Y
authors.initials: JY
authors.lastname: Hwang
authors.forename: P A
authors.initials: PA
authors.lastname: Gurbel
mesh_terms: D000244:Adenosine Diphosphate / Q000737:chemistry; D000328:Adult; D000368:Aged; D000483:Alleles; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics*; D044466:Asian People; D000077144:Clopidogrel; D015331:Cohort Studies; D065731:Cytochrome P-450 CYP2C19; D005260:Female; D005838:Genotype; D006579:Heterozygote; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D062645:Percutaneous Coronary Intervention; D010597:Pharmacogenetics; D010865:Pilot Projects; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D010979:Platelet Function Tests; D020641:Polymorphism, Single Nucleotide; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D010975:Platelet Aggregation Inhibitors; D000244:Adenosine Diphosphate; D000077144:Clopidogrel; D001189:Aryl Hydrocarbon Hydroxylases; C045793:CYP2C19 protein, human; D065731:Cytochrome P-450 CYP2C19; D013988:Ticlopidine