title: Comparison of ICD-10R, DSM-IV-TR and DSM-5 in an adult autism spectrum disorder diagnostic clinic.
abstract: An Autism Spectrum Disorder (ASD) diagnosis is often used to access services. We investigated whether ASD diagnostic outcome varied when DSM-5 was used compared to ICD-10R and DSM-IV-TR in a clinical sample of 150 intellectually able adults. Of those diagnosed with an ASD using ICD-10R, 56 % met DSM-5 ASD criteria. A further 19 % met DSM-5 (draft) criteria for Social Communication Disorder. Of those diagnosed with Autistic Disorder/Asperger Syndrome on DSM-IV-TR, 78 % met DSM-5 ASD criteria. Sensitivity of DSM-5 was significantly increased by reducing the number of criteria required for a DSM-5 diagnosis, or by rating 'uncertain' criteria as 'present', without sacrificing specificity. Reduced rates of ASD diagnosis may mean some ASD individuals will be unable to access clinical services.
authors.affiliation: Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, King's College, London, SE5 8AF, UK, ellie.wilson@kcl.ac.uk.
authors.forename: C Ellie
authors.initials: CE
authors.lastname: Wilson
authors.forename: Nicola
authors.initials: N
authors.lastname: Gillan
authors.forename: Deborah
authors.initials: D
authors.lastname: Spain
authors.forename: Dene
authors.initials: D
authors.lastname: Robertson
authors.forename: Gedeon
authors.initials: G
authors.lastname: Roberts
authors.forename: Clodagh M
authors.initials: CM
authors.lastname: Murphy
authors.forename: Stefanos
authors.initials: S
authors.lastname: Maltezos
authors.forename: Janneke
authors.initials: J
authors.lastname: Zinkstok
authors.forename: Katie
authors.initials: K
authors.lastname: Johnston
authors.forename: Christina
authors.initials: C
authors.lastname: Dardani
authors.forename: Chris
authors.initials: C
authors.lastname: Ohlsen
authors.forename: P Quinton
authors.initials: PQ
authors.lastname: Deeley
authors.forename: Michael
authors.initials: M
authors.lastname: Craig
authors.forename: Maria A
authors.initials: MA
authors.lastname: Mendez
authors.forename: Francesca
authors.initials: F
authors.lastname: Happé
authors.forename: Declan G M
authors.initials: DG
authors.lastname: Murphy
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D020817:Asperger Syndrome / Q000175:diagnosis; D001321:Autistic Disorder / Q000175:diagnosis; D002659:Child Development Disorders, Pervasive / Q000175:diagnosis*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D055815:Young Adult