title: Sectoral loss of myelin and axons in anterior ischemic optic neuropathy.
abstract: OBJECTIVE
  We report a case of focal myelinated nerve fiber (MNF) loss caused by anterior ischemic optic neuropathy.
  
  
  METHODS
  A 62-year-old woman with segmental MNF presented with anterior ischemic optic neuropathy. One year later, MNF lost superiorly, with preservation of inferior segment MNF. Spectral-domain optical coherence tomography of the optic nerve head and posterior pole retinal thickness showed localized thinning of superior nerve fibers (axons) and retinal thickness.
  
  
  CONCLUSIONS
  This case highlights the focal nature of anterior ischemic optic neuropathy and may be the first patient in whom sectoral loss of myelinated nerve fiber has been photographically documented.
authors.affiliation: Farabi Eye Research Center, Department of Ophthalmology, Tehran University of Medical Sciences, Tehran, Iran. masood219@gmail.com
authors.forename: Masoud Aghsaei
authors.initials: MA
authors.lastname: Fard
authors.forename: Sara
authors.initials: S
authors.lastname: Fakhree
mesh_terms: D001369:Axons / Q000473:pathology; D018450:Disease Progression; D005260:Female; D006801:Humans; D008875:Middle Aged; D009186:Myelin Sheath / Q000378:metabolism*; D009413:Nerve Fibers, Myelinated / Q000378:metabolism / Q000473:pathology*; D009898:Optic Disk / Q000378:metabolism / Q000473:pathology*; D018917:Optic Neuropathy, Ischemic / Q000378:metabolism / Q000473:pathology*; D012165:Retinal Ganglion Cells / Q000378:metabolism / Q000473:pathology*; D041623:Tomography, Optical Coherence / Q000379:methods