title: Primary Burkitt's Lymphoma Presenting as a Rapidly Growing Thyroid Mass.
abstract: A 31-year-old male patient presented with a rapidly growing neck mass with normal thyroid function tests. Ultrasonography showed thyroidal expansion, a hypoechoic nodule that completely filled the right lobe, and 2 hypoechoic lymphadenopathies in the right jugulodigastric chain. The patient underwent right total and left subtotal thyroidectomy, following the diagnosis of nodular goiter; however, postoperative histopathological evaluation demonstrated primary Burkitt's lymphoma of the thyroid gland. The tumor was staged as stage 1, and R-hyper-CVAD protocol (rituximab, hyperfractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone) was administered. The protocol was changed to R-CHOP after 4 cycles due to recurrent grade III/IV cytopenias and febrile neutropenia. The PET-CT scans performed after chemotherapy and at the 6-month follow-up were normal. In summary, we reported a case with a diagnosis of Burkitt's lymphoma, which is a rare type of primary thyroid lymphoma.
authors.affiliation: Department of Medical Oncology, Institute of Oncology, Istanbul University, Istanbul, Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Yildiz
authors.forename: Fatma
authors.initials: F
authors.lastname: Sen
authors.forename: Bahtiyar
authors.initials: B
authors.lastname: Toz
authors.forename: Leyla
authors.initials: L
authors.lastname: Kilic
authors.forename: Mehmet
authors.initials: M
authors.lastname: Agan
authors.forename: Mert
authors.initials: M
authors.lastname: Basaran
keywords: Burkitt's lymphoma; Chemotherapy; Thyroid