title: Draft Genome Sequence of Escherichia coli Strain ATCC 23502 (Serovar O5:K4:H4).
abstract: We report the 4.682-Mbp high-quality draft assembly of the Escherichia coli strain ATCC 23502 (serovar O5:K4:H4, also known as NCDC U1-41) genome. This uropathogenic strain, commonly referred to as E. coli K4, produces a glycosaminoglycan-like capsular polysaccharide with a backbone similar in structure to unsulfated chondroitin, a precursor to the nutraceutically and potentially pharmaceutically valuable compound chondroitin sulfate. Metabolic reconstruction of this genome will enable prediction of genetic engineering strategies leading to increased chondroitin production.
authors.affiliation: Department of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA.
authors.forename: Brady F
authors.initials: BF
authors.lastname: Cress
authors.forename: Zachary R
authors.initials: ZR
authors.lastname: Greene
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Linhardt
authors.forename: Mattheos A G
authors.initials: MA
authors.lastname: Koffas