title: [Timely estimation of risk factors of coronary heart disease as a basis of prevention of its complications].
abstract: We compared the prevalence and duration of action of common risk factors (RF) of arterial hypertension (AH), smoking, alcohol abuse, excess consumption of animal fats and carbohydrates, psychoemotional stress, inherited risk of coronary heart disease (CHD), AH, diabetes mellitus (DM), overweight/obesity, hypercholesterolemia (HC) and hypertriglyceridemia (HTG) contributing to combined cardiovascular pathology. In addition, RF of myocardial infarction (MI) were elucidated. The study involved 190 patients with CHD including 82 (43.2%) and 108 (56.8%) (mean age 53. 0 +/- 0.6 yr) suffering functional class I-III angina of effort (AE), metabolic syndrome and DM2. A combination of such RF as AH, HC, and HTG, psychoemotional stress, unhealthy diet, overweight/obesity DM2, smoking, and alcohol abuse were found to be associated with CHD and MI. Four RF were identified in 37.4 and 31.1% of the men and women respectively, 5 FR in 33.1 and 39.5%, 6 RF in 29.5 and 15.3%; 7 RF were revealed in 14.1% of the men. The history of IM was documented in 101 (53.2%) patients, Q-wave IM in 55 (28.9%), non-Q-wave MI in 46 (24.3%). Q-wave MI occurred in 142 and 14.7% of men and women respectively; non-Q-wave MI occurred 1.2 times more frequently in women than in men. It is concluded that early diagnosis of RF in young and middle-aged subjects may promote prevention or slow down progression of metabolic syndrome, AH, CHD, and DM2.
authors.forename: S A
authors.initials: SA
authors.lastname: Matveeva
mesh_terms: D003327:Coronary Disease / Q000150:complications / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications* / Q000453:epidemiology; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D015995:Prevalence; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology; D012907:Smoking / Q000453:epidemiology*; D013997:Time Factors