title: Physician perceptions and beliefs of phase I trials in pediatric oncology.
abstract: The identification and referral of candidate patients for phase I trials relies heavily on pediatric oncologists who must balance their own perceptions of phase I trials with the desires of the patient and his/her family. A survey was sent to 419 physicians practicing pediatric oncology at 30 different institutions. Results indicated significant differences between physicians who practiced at institutions that participated in phase I consortia versus those who did not. The findings of the survey may be used to enhance the design and execution of phase I trials and to educate oncologists about the goals of phase I trials.
authors.affiliation: Department of Psychology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA.
authors.forename: Margaux B
authors.initials: MB
authors.lastname: Gilliam
authors.forename: Avi
authors.initials: A
authors.lastname: Madan-Swain
authors.forename: Julia M
authors.initials: JM
authors.lastname: Adams
authors.forename: Joseph G
authors.initials: JG
authors.lastname: Pressey
mesh_terms: D000293:Adolescent; D001291:Attitude of Health Personnel; D002648:Child; D002675:Child, Preschool; D017321:Clinical Trials, Phase I as Topic; D003469:Culture; D004502:Education, Medical, Continuing; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009369:Neoplasms / Q000628:therapy*; D010820:Physicians