title: δ-Unsaturated γ-amino acids: enantiodivergent synthesis and cell imaging studies.
abstract: Synthesis of both enantiomers of δ-unsaturated γ-amino acids via the enantiodivergent [3,3]-sigmatropic rearrangement strategy is reported. Excellent enantiomeric excess > 94% are observed in the strategy. Cell permeability of a fluorescent amino acid derivative is evaluated by live-cell imaging.
authors.affiliation: Department of Chemistry, Mendeleev Block, Indian Institute of Science Education and Research Pune, India.
authors.forename: Dnyaneshwar
authors.initials: D
authors.lastname: Kand
authors.forename: Dinesh Pratapsinh
authors.initials: DP
authors.lastname: Chauhan
authors.forename: Mayurika
authors.initials: M
authors.lastname: Lahiri
authors.forename: Pinaki
authors.initials: P
authors.lastname: Talukdar
mesh_terms: D000596:Amino Acids / Q000737:chemistry* / Q000494:pharmacology; D005453:Fluorescence; D006367:HeLa Cells; D006801:Humans; D046529:Microscopy, Electron, Transmission; D008856:Microscopy, Fluorescence; D010539:Permeability; D013237:Stereoisomerism
chemical_list: D000596:Amino Acids