title: Role of prolactin-like protein (PRL-L) in cold-induced increase of muscle mass in chicks.
abstract: This study examined the hypothesis that a novel prolactin-like protein gene (PRL-L) is involved in cold-induced growth of skeletal muscle in chicks. Six-day-old chicks (Gallus gallus domesticus) were exposed to cold at 4°C or kept warm at 30°C for 24h. Cold exposure induced significant increases in PRL-L expression that coincided with increases in the weight of the sartorius muscle, which comprises both fast- and slow-twitch fibers. Meanwhile, no induction of PRL-L mRNA was observed in the heart, liver, kidney, brain, or fat. Myoblast cells that expressed PRL-L mRNA grew faster than untransduced cells in media containing 2% serum. These results suggested that PRL-L might be involved in in controlling cold-induced muscle growth of chicks.
authors.affiliation: Graduate School of Life and Environmental Sciences, University of Tsukuba, Ibaraki 305-8572, Japan. ijiri@chem.agri.kagoshima-u.ac.jp
authors.forename: Daichi
authors.initials: D
authors.lastname: Ijiri
authors.forename: Asami
authors.initials: A
authors.lastname: Higuchi
authors.forename: Akito
authors.initials: A
authors.lastname: Saegusa
authors.forename: Moe
authors.initials: M
authors.lastname: Miura
authors.forename: Tomoko
authors.initials: T
authors.lastname: Matsubara
authors.forename: Yukio
authors.initials: Y
authors.lastname: Kanai
authors.forename: Akira
authors.initials: A
authors.lastname: Ohtsuka
authors.forename: Miho
authors.initials: M
authors.lastname: Hirabayashi
mesh_terms: D000818:Animals; D002645:Chickens; D003080:Cold Temperature; D018482:Muscle, Skeletal / Q000378:metabolism*; D011257:Pregnancy Proteins / Q000378:metabolism*
chemical_list: D011257:Pregnancy Proteins