title: Efficacy of ranolazine in a patient with idiopathic dilated cardiomyopathy and electrical storm.
abstract: A case of idiopathic dilated cardiomyopathy with an arrhythmic storm refractory to the usual antiarrhythmic therapy will be reported. The idiopathic structural heart disease of the patient is a vulnerable anatomic substrate in itself, for electrical instability and reentry mechanism, because of heterogeneous areas of scarred myocardium and low left ventricle ejection fraction. In this case, the ranolazine administration was safe and effective for the prevention of further electrical storms.
authors.affiliation: Department of Applied Experimental Medicine, University of Brescia, Brescia, Italy. enrico.vizzardi@tin.it
authors.forename: E
authors.initials: E
authors.lastname: Vizzardi
authors.forename: A
authors.initials: A
authors.lastname: D'Aloia
authors.forename: F
authors.initials: F
authors.lastname: Salghetti
authors.forename: O
authors.initials: O
authors.lastname: Aljassim
authors.forename: A
authors.initials: A
authors.lastname: Raweh
authors.forename: I
authors.initials: I
authors.lastname: Bonadei
authors.forename: L
authors.initials: L
authors.lastname: Bontempi
authors.forename: A
authors.initials: A
authors.lastname: Curnis
mesh_terms: D000083:Acetanilides / Q000008:administration & dosage / Q000627:therapeutic use*; D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D017147:Defibrillators, Implantable; D004562:Electrocardiography; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D010879:Piperazines / Q000008:administration & dosage / Q000627:therapeutic use*; D000069458:Ranolazine; D017180:Tachycardia, Ventricular / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D000083:Acetanilides; D000889:Anti-Arrhythmia Agents; D010879:Piperazines; D000069458:Ranolazine