title: Pentafulvene-derived η3-allyltitanocenes as intermediates for the stereoselective functionalization of 5-membered carbocycles.
abstract: Allyltitanocene complexes can be generated by reacting pentafulvenes with DIBAL-H and Cp2TiCl2. Their coupling with aldehydes affords homoallylic alcohols in a highly regio- and stereoselective manner. The potential of this method for the stereoselective synthesis of cyclopentane derivatives is illustrated.
authors.affiliation: Institut de Chimie Moléculaire, CNRS (UMR 7312) and Université de Reims, 51687 Reims Cedex 2, France.
authors.forename: Jomy
authors.initials: J
authors.lastname: Joseph
authors.forename: Florian
authors.initials: F
authors.lastname: Jaroschik
authors.forename: K V
authors.initials: KV
authors.lastname: Radhakrishnan
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Vasse
authors.forename: Jan
authors.initials: J
authors.lastname: Szymoniak
mesh_terms: D000438:Alcohols / Q000138:chemical synthesis* / Q000737:chemistry; D003517:Cyclopentanes / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D013237:Stereoisomerism; D014025:Titanium / Q000737:chemistry*
chemical_list: D000438:Alcohols; D003517:Cyclopentanes; D009942:Organometallic Compounds; C017332:fulvene; D014025:Titanium