title: The 19th annual Prostate Cancer Foundation scientific retreat.
abstract: Prostate Cancer Foundation (PCF) convened its 19th Annual Scientific Retreat October 25-27, 2012, in Carlsbad, CA. Each year, this event brings together diverse researchers in a collaborative forum to present and discuss new and largely unpublished findings for prostate cancer diagnosis, prognosis, and treatment and defines the challenges to ending this disease as a threat to life and well-being. Several themes resonated at the multidisciplinary meeting, notably (i) the roles of field cancerization, tumor microenvironment, epithelial plasticity, signal transduction pathways in cancer progression, and disease resistance; (ii) intratumoral heterogeneity and consequences for precision medicine; (iii) resistance mechanisms to androgen axis inhibitors; and (iv) advances in molecular imaging and therapeutics for better detection and treatment.
authors.affiliation: Prostate Cancer Foundation, Santa Monica, CA 90401, USA.
authors.forename: Guneet
authors.initials: G
authors.lastname: Walia
authors.forename: Kenneth J
authors.initials: KJ
authors.lastname: Pienta
authors.forename: Jonathan W
authors.initials: JW
authors.lastname: Simons
authors.forename: Howard R
authors.initials: HR
authors.lastname: Soule
mesh_terms: D000818:Animals; D006801:Humans; D008297:Male; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000188:drug therapy / Q000235:genetics* / Q000378:metabolism / Q000473:pathology*; D015398:Signal Transduction; D059016:Tumor Microenvironment / Q000187:drug effects / Q000235:genetics