title: Iodine(III)-mediated umpolung of bromide salts for the ethoxybromination of enamides.
abstract: Using (diacetoxyiodo)benzene in conjunction with simple bromide salts in ethanol allows the regioselective ethoxybromination of a wide range of enamides, thus yielding highly versatile α-bromo hemiaminals, which can then be engaged in a broad array of transformations.
authors.affiliation: Centre de Recherche de Gif-sur-Yvette, Institut de Chimie des Substances Naturelles, CNRS, 91198 Gif-sur-Yvette Cedex, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Nocquet-Thibault
authors.forename: Pascal
authors.initials: P
authors.lastname: Retailleau
authors.forename: Kevin
authors.initials: K
authors.lastname: Cariou
authors.forename: Robert H
authors.initials: RH
authors.lastname: Dodd
mesh_terms: D000577:Amides / Q000737:chemistry*; D001555:Benzene Derivatives / Q000737:chemistry*; D001965:Bromides / Q000737:chemistry*; D002384:Catalysis; D006842:Hydrocarbons, Brominated / Q000138:chemical synthesis* / Q000737:chemistry; D007455:Iodine / Q000737:chemistry*; D018020:Lithium Compounds / Q000737:chemistry*; D015394:Molecular Structure; D012492:Salts; D013237:Stereoisomerism
chemical_list: D000577:Amides; D001555:Benzene Derivatives; D001965:Bromides; D006842:Hydrocarbons, Brominated; D018020:Lithium Compounds; D012492:Salts; C040949:lithium bromide; D007455:Iodine