title: A rare combination of sebaceoma with carcinomatous change (sebaceous carcinoma), trichoblastoma, and poroma arising from a nevus sebaceus.
abstract: We report a case of a 48-year-old Malay female who presented with multiple tumors arising from a large nevus sebaceus on her right parieto-temporal scalp. Histologically, the tumors corresponded to a sebaceoma with carcinomatous change, a poroma and a trichoblastoma. Immunohistochemical staining of the sebaceous tumor with p53 showed strong within the areas of carcinomatous change, while there was negative to weak staining within the sebaceoma-like areas. A discussion on the potential secondary neoplasms from a nevus sebaceus ensues, with a review of this literature on multiple tumors from a nevus sebaceus.
authors.affiliation: National Skin Centre, Singapore, Singapore. etiennewang@gmail.com
authors.forename: Etienne
authors.initials: E
authors.lastname: Wang
authors.forename: Joyce Siong-See
authors.initials: JS
authors.lastname: Lee
authors.forename: Dmitry V
authors.initials: DV
authors.lastname: Kazakov
mesh_terms: D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology*; D054000:Nevus, Sebaceous of Jadassohn / Q000473:pathology*; D057091:Poroma / Q000473:pathology*; D012626:Sebaceous Gland Neoplasms / Q000473:pathology / Q000556:secondary