title: Pharmacotherapy prevention and management of nutritional deficiencies post Roux-en-Y gastric bypass.
abstract: Roux-en-Y gastric bypass is the most commonly performed bariatric procedure. It is associated with nutritional deficiencies due to gastric reduction, intestinal bypass, reduced caloric intake, avoidance of nutrient-rich foods, noncompliance with supplementation and poor food tolerability. Although there are multiple publications on this topic, there is a lack of consistent guidance for the healthcare practitioner caring for the bariatric patient. This article will encompass literature reviewing the pharmacotherapy approach to prevention and management of nutritional deficiencies since the American Society of Metabolic and Bariatric Surgery guidelines were published in 2008.
authors.affiliation: Brigham & Women's Hospital, Boston, MA, USA.
authors.forename: Radmila
authors.initials: R
authors.lastname: Levinson
authors.forename: Jon B
authors.initials: JB
authors.lastname: Silverman
authors.forename: Jennifer G
authors.initials: JG
authors.lastname: Catella
authors.forename: Iwona
authors.initials: I
authors.lastname: Rybak
authors.forename: Hina
authors.initials: H
authors.lastname: Jolin
authors.forename: Kellene
authors.initials: K
authors.lastname: Isom
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D002118:Calcium / Q000172:deficiency; D003300:Copper / Q000172:deficiency; D019587:Dietary Supplements; D005260:Female; D015390:Gastric Bypass / Q000009:adverse effects*; D017408:Guidelines as Topic; D006801:Humans; D008297:Male; D044342:Malnutrition / Q000188:drug therapy* / Q000209:etiology* / Q000517:prevention & control; D009767:Obesity, Morbid / Q000150:complications / Q000601:surgery*; D010349:Patient Compliance; D013832:Thiamine Deficiency / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D014481:United States; D014802:Vitamin A Deficiency / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D014806:Vitamin B 12 Deficiency / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D014808:Vitamin D Deficiency / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D014815:Vitamins / Q000627:therapeutic use*
chemical_list: D014815:Vitamins; D003300:Copper; D002118:Calcium
references.citation: Obes Surg. 2011 Apr;21(4):479-84
references.pmid: 21336558
references.citation: Obes Surg. 2009 Jun;19(6):738-44
references.pmid: 18392900
references.citation: Mt Sinai J Med. 2010 Sep-Oct;77(5):431-45
references.pmid: 20960547
references.citation: Obes Surg. 1999 Apr;9(2):150-4
references.pmid: 10340768
references.citation: Nutr Clin Pract. 2009 Apr-May;24(2):217-26
references.pmid: 19321896
references.citation: J Obes. 2011;2011:141024
references.pmid: 21772998
references.citation: N Engl J Med. 2012 Jul 26;367(4):385-6
references.pmid: 22830482
references.citation: Expert Rev Gastroenterol Hepatol. 2010 Dec;4(6):781-94
references.pmid: 21108597
references.citation: World J Gastroenterol. 2009 Oct 7;15(37):4644-52
references.pmid: 19787827
references.citation: Am Fam Physician. 2003 Mar 1;67(5):979-86
references.pmid: 12643357
references.citation: Gastroenterol Clin North Am. 2010 Mar;39(1):109-24
references.pmid: 20202584
references.citation: Surv Ophthalmol. 2010 Jul-Aug;55(4):386-92
references.pmid: 20451943
references.citation: Obes Surg. 2008 Mar;18(3):288-93
references.pmid: 18214631
references.citation: Int J Obes (Lond). 2012 Mar;36(3):328-35
references.pmid: 21876546
references.citation: Rev Assoc Med Bras (1992). 2011 Jan-Feb;57(1):113-20
references.pmid: 21390468
references.citation: Surg Obes Relat Dis. 2008 Sep-Oct;4(5 Suppl):S109-84
references.pmid: 18848315
references.citation: Obes Surg. 2011 Dec;21(12):1971-4
references.pmid: 21688116
references.citation: Surg Obes Relat Dis. 2008 Sep-Oct;4(5 Suppl):S73-108
references.pmid: 18490202
references.citation: Br J Clin Pharmacol. 2003 Dec;56(6):635-8
references.pmid: 14616423
references.citation: Am J Clin Nutr. 2011 Oct;94(4):1004-11
references.pmid: 21865332
references.citation: Lancet Neurol. 2007 May;6(5):442-55
references.pmid: 17434099
references.citation: J Am Board Fam Med. 2006 Mar-Apr;19(2):191-4
references.pmid: 16513908
references.citation: J Emerg Med. 2012 Nov;43(5):811-4
references.pmid: 19406605
references.citation: Obesity (Silver Spring). 2009 Apr;17(4):827-31
references.pmid: 19148115
references.citation: Obes Surg. 2010 Dec;20(12):1660-70
references.pmid: 20706804
references.citation: J Obes. 2011;2011:634614
references.pmid: 21274274
references.citation: Diabetes Care. 2005 Feb;28(2):481-4
references.pmid: 15677821
references.citation: Plast Reconstr Surg. 2008 Aug;122(2):604-613
references.pmid: 18626380
references.citation: Am Fam Physician. 2011 Jun 15;83(12):1425-30
references.pmid: 21671542
references.citation: Am Surg. 2006 Dec;72(12):1196-202; discussion 1203-4
references.pmid: 17216818
references.citation: Obes Surg. 2009 Jan;19(1):56-65
references.pmid: 18542847
references.citation: Obes Surg. 2006 May;16(5):603-6
references.pmid: 16687029
references.citation: J Clin Endocrinol Metab. 2008 Mar;93(3):677-81
references.pmid: 18089691
references.citation: J Obes. 2011;2011:
references.pmid: 20871833
references.citation: Arch Neurol. 2003 Dec;60(12):1782-5
references.pmid: 14676057
references.citation: Ann Fr Anesth Reanim. 2003 Jun;22(6):557-9
references.pmid: 12893385
references.citation: JPEN J Parenter Enteral Nutr. 2006 Sep-Oct;30(5):446-50
references.pmid: 16931615
references.citation: J Clin Endocrinol Metab. 2010 Nov;95(11):4823-43
references.pmid: 21051578
references.citation: Obes Surg. 2009 May;19(5):590-4
references.pmid: 18850253
references.citation: World J Gastroenterol. 2010 Apr 21;16(15):1867-70
references.pmid: 20397264
references.citation: JAMA. 2004 Oct 13;292(14):1724-37
references.pmid: 15479938
references.citation: Gastroenterol Nurs. 2011 Sep-Oct;34(5):367-74
references.pmid: 21979398
references.citation: J Surg Res. 2010 Dec;164(2):198-202
references.pmid: 20850786
references.citation: Am J Clin Nutr. 1981 Nov;34(11):2359-63
references.pmid: 7304477
references.citation: Am J Clin Nutr. 2008 May;87(5):1128-33
references.pmid: 18469230
references.citation: Obes Res. 1998 Sep;6 Suppl 2:51S-209S
references.pmid: 9813653
references.citation: Surg Obes Relat Dis. 2006 Mar-Apr;2(2):98-103; discussion 104
references.pmid: 16925330
references.citation: Surg Obes Relat Dis. 2010 Nov-Dec;6(6):653-7
references.pmid: 20947440
references.citation: Cleve Clin J Med. 2006 Nov;73(11):993-1007
references.pmid: 17128540
references.citation: Curr Treat Options Neurol. 2010 Jan;12(1):29-36
references.pmid: 20842487
references.citation: Obes Surg. 2009 Feb;19(2):173-179
references.pmid: 18795378
references.citation: Surg Obes Relat Dis. 2009 Jul-Aug;5(4):444-9
references.pmid: 18996761
references.citation: Obes Surg. 2005 Feb;15(2):145-54
references.pmid: 15802055
references.citation: Pediatr Clin North Am. 2009 Oct;56(5):1105-21
references.pmid: 19931066
references.citation: South Med J. 2009 Oct;102(10):1025-31
references.pmid: 19738526
references.citation: Nutrition. 2010 Nov-Dec;26(11-12):1031-7
references.pmid: 20363593