title: Functional genomics to identify unforeseen cancer drug targets.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Kemp
authors.forename: Carla
authors.initials: C
authors.lastname: Grandori
mesh_terms: D000818:Animals; D061067:Antibodies, Monoclonal, Humanized / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000494:pharmacology*; D064007:Ataxia Telangiectasia Mutated Proteins; D001549:Benzamides / Q000494:pharmacology; D001943:Breast Neoplasms / Q000188:drug therapy / Q000235:genetics; D047389:Casein Kinase I / Q000235:genetics; D018797:Cell Cycle Proteins / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics; D005260:Female; D016259:Genes, myc; D011905:Genes, ras; D023281:Genomics / Q000379:methods*; D006801:Humans; D000068877:Imatinib Mesylate; D007938:Leukemia / Q000188:drug therapy / Q000235:genetics; D051379:Mice; D058990:Molecular Targeted Therapy / Q000379:methods*; D009154:Mutation; D010879:Piperazines / Q000494:pharmacology; D017346:Protein Serine-Threonine Kinases / Q000235:genetics; D011743:Pyrimidines / Q000494:pharmacology; D034622:RNA Interference; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000037:antagonists & inhibitors; D000068878:Trastuzumab; D025521:Tumor Suppressor Proteins / Q000235:genetics
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D064007:Ataxia Telangiectasia Mutated Proteins; D001549:Benzamides; D047389:Casein Kinase I; D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; D000068877:Imatinib Mesylate; D010879:Piperazines; D017346:Protein Serine-Threonine Kinases; D011743:Pyrimidines; D018719:Erb-b2 Receptor Tyrosine Kinases; D000068878:Trastuzumab; D025521:Tumor Suppressor Proteins; C508053:ERBB2 protein, human; C576324:ATM protein, human; C576325:Atm protein, mouse