title: Plant secretome - from cellular process to biological activity.
abstract: Recent studies suggest that plants secrete a large number of proteins and peptides into the extracellular space. Secreted proteins play a crucial role in stress response, communication and development of organisms. Here we review the current knowledge of the secretome of more than ten plant species, studied in natural conditions or during (a)biotic stress. This review not only deals with the classical secretory route via endoplasmic reticulum and Golgi followed by proteins containing a known N-terminal signal peptide, but also covers new findings about unconventional secretion of leaderless proteins. We describe alternative secretion pathways and the involved compartments like the recently discovered EXPO. The well characterized secreted peptides that function as ligands of receptor proteins exemplify the biological significance and activity of the secretome. This article is part of a Special Issue entitled: An Updated Secretome.
authors.affiliation: Center for Plant Molecular Biology (ZMBP), University of Tübingen, Auf der Morgenstelle 3, 72076 Tübingen, Germany.
authors.forename: Cornelia
authors.initials: C
authors.lastname: Krause
authors.forename: Sandra
authors.initials: S
authors.lastname: Richter
authors.forename: Christian
authors.initials: C
authors.lastname: Knöll
authors.forename: Gerd
authors.initials: G
authors.lastname: Jürgens
mesh_terms: D018521:Plant Physiological Phenomena; D010940:Plant Proteins / Q000737:chemistry / Q000378:metabolism*; D010944:Plants / Q000737:chemistry / Q000378:metabolism; D021382:Protein Sorting Signals; D020543:Proteome / Q000737:chemistry / Q000378:metabolism*; D012098:Reproduction; D055571:Secretory Pathway
chemical_list: D010940:Plant Proteins; D021382:Protein Sorting Signals; D020543:Proteome
keywords: Arabidopsis; Development; Interaction; Peptide; Secretion; Signaling