title: Redox-Responsive, Core Cross-Linked Polyester Micelles.
abstract: Monomethoxy poly(ethylene glycol)-b-poly(Tyr(alkynyl)-OCA), a biodegradable amphiphilic block copolymer, was synthesized by means of ring-opening polymerization of 5-(4-(prop-2-yn-1-yloxy)benzyl)-1,3-dioxolane-2,4-dione (Tyr(alkynyl)-OCA) and used to prepare core cross-linked polyester micelles via click chemistry. Core cross-linking not only improved the structural stability of the micelles but also allowed controlled release of cargo molecules in response to the reducing reagent. This new class of core cross-linked micelles can potentially be used in controlled release and drug delivery applications.
authors.affiliation: Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, 1304 W. Green Street, Urbana, IL, 61801, USA ; Institute of Nano- and Bio-polymeric Materials, School of Material Science and Engineering, Tongji University, Shanghai, 200092, China.
authors.forename: Zhonghai
authors.initials: Z
authors.lastname: Zhang
authors.forename: Lichen
authors.initials: L
authors.lastname: Yin
authors.forename: Chunlai
authors.initials: C
authors.lastname: Tu
authors.forename: Ziyuan
authors.initials: Z
authors.lastname: Song
authors.forename: Yanfeng
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yunxiang
authors.initials: Y
authors.lastname: Xu
authors.forename: Rong
authors.initials: R
authors.lastname: Tong
authors.forename: Qin
authors.initials: Q
authors.lastname: Zhou
authors.forename: Jie
authors.initials: J
authors.lastname: Ren
authors.forename: Jianjun
authors.initials: J
authors.lastname: Cheng
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