title: Diagnosis and management of Q fever--United States, 2013: recommendations from CDC and the Q Fever Working Group.
abstract: Q fever, a zoonotic disease caused by the bacterium Coxiella burnetii, can cause acute or chronic illness in humans. Transmission occurs primarily through inhalation of aerosols from contaminated soil or animal waste. No licensed vaccine is available in the United States. Because many human infections result in nonspecific or benign constitutional symptoms, establishing a diagnosis of Q fever often is challenging for clinicians. This report provides the first national recommendations issued by CDC for Q fever recognition, clinical and laboratory diagnosis, treatment, management, and reporting for health-care personnel and public health professionals. The guidelines address treatment of acute and chronic phases of Q fever illness in children, adults, and pregnant women, as well as management of occupational exposures. These recommendations will be reviewed approximately every 5 years and updated to include new published evidence.
authors.affiliation: National Center for Emerging and Zoonotic Infectious Diseases, CDC, Atlanta, Georgia, USA.
authors.forename: Alicia
authors.initials: A
authors.lastname: Anderson
authors.forename: Henk
authors.initials: H
authors.lastname: Bijlmer
authors.forename: Pierre-Edouard
authors.initials: PE
authors.lastname: Fournier
authors.forename: Stephen
authors.initials: S
authors.lastname: Graves
authors.forename: Joshua
authors.initials: J
authors.lastname: Hartzell
authors.forename: Gilbert J
authors.initials: GJ
authors.lastname: Kersh
authors.forename: Gijs
authors.initials: G
authors.lastname: Limonard
authors.forename: Thomas J
authors.initials: TJ
authors.lastname: Marrie
authors.forename: Robert F
authors.initials: RF
authors.lastname: Massung
authors.forename: Jennifer H
authors.initials: JH
authors.lastname: McQuiston
authors.forename: William L
authors.initials: WL
authors.lastname: Nicholson
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Paddock
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Sexton
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000818:Animals; D000829:Animals, Domestic; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002908:Chronic Disease; D004318:Doxycycline / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D011247:Pregnancy; D011778:Q Fever / Q000175:diagnosis* / Q000188:drug therapy*; D012306:Risk; D014481:United States / Q000453:epidemiology; D015047:Zoonoses
chemical_list: D000900:Anti-Bacterial Agents; D004318:Doxycycline