title: Protein-coated nanofibers for promotion of T cell activity.
abstract: We have demonstrated that stable Concanavalin A (Con A)-coated supramolecular nanofibers can be constructed by complexation of self-assembled mannose nanofibers with Con A. The extended multivalent Con A nanofibers bind strongly to T cell surfaces and promote T cell activation.
authors.affiliation: The State Key Lab of Supramolecular Structure and Materials, Department of Chemistry, Jilin University, Changchun 130012, PR China.
authors.forename: Taehoon
authors.initials: T
authors.lastname: Kim
authors.forename: Hyojin
authors.initials: H
authors.lastname: Lee
authors.forename: Yongju
authors.initials: Y
authors.lastname: Kim
authors.forename: Jwa-Min
authors.initials: JM
authors.lastname: Nam
authors.forename: Myongsoo
authors.initials: M
authors.lastname: Lee
mesh_terms: D003208:Concanavalin A / Q000737:chemistry / Q000276:immunology*; D006801:Humans; D055767:Immobilized Proteins / Q000737:chemistry / Q000276:immunology*; D019169:Jurkat Cells; D008213:Lymphocyte Activation; D008958:Models, Molecular; D057139:Nanofibers / Q000737:chemistry* / Q000648:ultrastructure; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology*
chemical_list: D055767:Immobilized Proteins; D003208:Concanavalin A