title: Highly stereoselective synthesis of trisubstituted cyclohexanols using a guanidine-catalyzed tandem Henry-Michael reaction.
abstract: A highly diastereoselective (dr >99:1) and enantioselective (ee value up to 98%) synthesis of trisubstituted cyclohexanols was achieved by using a tandem Henry--Michael reaction between nitromethane and 7-oxo-hept-5-enals catalyzed by the Misaki-Sugimura guanidine.
authors.affiliation: Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249-0698, USA.
authors.forename: Qipu
authors.initials: Q
authors.lastname: Dai
authors.forename: Huicai
authors.initials: H
authors.lastname: Huang
authors.forename: John Cong-Gui
authors.initials: JC
authors.lastname: Zhao