title: Risk factors of choledocholithiasis formation after liver transplantation.
abstract: Systematic study of risk factors for biliary stone post-liver transplantation is rarely performed. To investigate the risk factor of choledocholithiasis formation after liver transplantation, we conducted a case-control study. Fourteen patients were selected into a study group. The stones of the bile duct of the patients were confirmed and treated successfully by endoscopic retrograde cholangiopancreatography. For univariate analysis, we selected carefully some potential risk factors such as cold ischemia time, warm ischemia time, and biliary stricture. The results revealed that cold ischemia time and biliary stenosis were significant predictors. But multivariate analysis revealed that only biliary stenosis was a significant risk factor. In conclusion, biliary stenosis is a risk factor of bile duct stones formation after liver transplantation. Endoscopic retrograde cholangiopancreatography is effective and safe in the diagnosis or treatment of bile duct stones after liver transplantation.
authors.affiliation: Key Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Yu
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.forename: Yun-Sheng
authors.initials: YS
authors.lastname: Qin
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Zhou
authors.forename: Ming-Yue
authors.initials: MY
authors.lastname: Cai
authors.forename: Song-Feng
authors.initials: SF
authors.lastname: Yu
authors.forename: Qing-Hong
authors.initials: QH
authors.lastname: Ke
authors.forename: Shu-Sen
authors.initials: SS
authors.lastname: Zheng
mesh_terms: D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002760:Cholangiopancreatography, Endoscopic Retrograde; D042883:Choledocholithiasis / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D002779:Cholestasis / Q000209:etiology; D003251:Constriction, Pathologic; D005260:Female; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome