title: HGV-HCV/HBV co-infection in India: A pilot study.
abstract: BACKGROUND
  Hepatitis G virus (HGV) is newly identified virus, transmitted by infected blood and blood products. Effect of HGV infection on liver diseases is not well known.
  
  
  OBJECTIVE
  Co-infection of HGV with hepatitis B virus (HBV) and hepatitis C virus (HCV) infection has been reported however; very limited data is available from India. Therefore, we have performed a pilot study for the presence of co-infection of HGV in chronic liver disease patients.
  
  
  METHODS
  The study was performed in research laboratory at P.D. Hinduja National hospital and Medical research center, Mahim, Mumbai. Prospective study was designed.
  
  
  METHODS
  Forty HBV, HCV related chronic liver disease patients were studied. Forty randomly selected voluntary healthy blood donors visiting our blood bank were included as controls. Serum bilirubin, alanine aminotransferase (ALT), Aspartate aminotransferase (AST) and alkaline phosphatase (ALP) were estimated. HGV infection was detected by using reverse transcriptase molony murine leukemia virus (M-MLV) with the help of HGV 340/625IC kit (Sacace, Italy).
  
  
  CONCLUSIONS
  One HCV positive patient had infection with HGV among 40 HBV/HCV chronic liver disease patients.
authors.affiliation: Department of Research, Transfusion Medicine, P.D. Hinduja National Hospital and Medical Research Centre, Mumbai, India.
authors.forename: Amruta D
authors.initials: AD
authors.lastname: Pathare
authors.forename: Anand S
authors.initials: AS
authors.lastname: Deshpande
keywords: Hepatitis B virus; hepatitis C virus; hepatitis G virus; reverse transcription PCR
references.citation: J Med Virol. 1996 Sep;50(1):97-103
references.pmid: 8890047
references.citation: Am J Gastroenterol. 1997 Nov;92(11):1992-6
references.pmid: 9362178
references.citation: Science. 1996 Jan 26;271(5248):505-8
references.pmid: 8560265
references.citation: Gut. 1998 Jan;42(1):107-11
references.pmid: 9505895
references.citation: J Clin Microbiol. 1996 Nov;34(11):2660-4
references.pmid: 8897160
references.citation: J Med Virol. 1996 Sep;50(1):71-4
references.pmid: 8890043
references.citation: Indian J Med Res. 1999 Aug;110:37-42
references.pmid: 10573652
references.citation: J Assoc Physicians India. 2000 Aug;48(8):818-9
references.pmid: 11273477
references.citation: Gastroenterology. 1997 Apr;112(4):1265-70
references.pmid: 9098011
references.citation: J Hepatol. 1996 Nov;25(5):763-8
references.pmid: 8938557
references.citation: J Viral Hepat. 1996 Nov;3(6):307-16
references.pmid: 8947882
references.citation: N Engl J Med. 1997 Mar 13;336(11):747-54
references.pmid: 9052652
references.citation: Dig Dis Sci. 2008 May;53(5):1383-9
references.pmid: 17934857
references.citation: N Engl J Med. 1996 Jun 6;334(23):1485-90
references.pmid: 8618602
references.citation: Ann Intern Med. 1997 Jun 1;126(11):874-81
references.pmid: 9163288
references.citation: Jpn J Infect Dis. 2006 Feb;59(1):25-30
references.pmid: 16495630
references.citation: World J Gastroenterol. 2008 Aug 14;14(30):4725-34
references.pmid: 18720531
references.citation: Med J Armed Forces India. 2005 Oct;61(4):333-5
references.pmid: 27407800