title: Care of the cholestatic patient.
abstract: Cholestasis is defined as impairment of bile formation or bile flow. Care of the patient with cholestatic features is dependent on identifying the cause of the cholestasis, initiating appropriate treatment of reversible conditions, and the recognition and management of cholestasis-specific complications. Cholestasis may include extrahepatic ducts and intrahepatic bile ducts, or may be limited to one or the other. Jaundice and pruritus are the hallmarks of cholestasis clinically but biochemical evidence may, and often does, precede the clinical manifestations.
authors.affiliation: Cholestatic Liver Disease Study Group, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55901, USA. Gossard.Andrea@mayo.edu
authors.forename: Andrea A
authors.initials: AA
authors.lastname: Gossard
mesh_terms: D001361:Avitaminosis / Q000188:drug therapy / Q000209:etiology; D015209:Cholangitis, Sclerosing / Q000150:complications; D002779:Cholestasis / Q000150:complications / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D050171:Dyslipidemias / Q000188:drug therapy / Q000209:etiology; D005221:Fatigue / Q000209:etiology / Q000628:therapy; D006801:Humans; D006975:Hypertension, Portal / Q000188:drug therapy / Q000209:etiology; D008105:Liver Cirrhosis, Biliary / Q000150:complications / Q000188:drug therapy; D010024:Osteoporosis / Q000188:drug therapy / Q000209:etiology; D011537:Pruritus / Q000209:etiology / Q000628:therapy