title: [Spousal concordance of blood pressure levels (results of 17-year follow-up)].
abstract: Study aim was investigation of blood pressure levels (BP) in spouses and assessment of the role of arterial hypertension (AH) in a spouse as risk factor (RF) of AH in a 17-years prospective study. Primary study based on a random sample of citizens of Tomsk (1546 men and women aged 20-59 years) was carried out in 1988-1991. At repeat study which was carried out in 2002-2005 we obtained data on AH and end points from 81.2% of initial population. Cohort family study comprised 427 family couples. Relative risk (RR) of AH development in men in case of AH of a female spouse was 1.63 (95% confidence interval [CI] 1.14 to 2.33). RR of AH development in a women in this situation was 1.5 (95%CI 1.13 to 1.99). Husbands AH was associated with 5.2% elevation of systolic BP (SBP) (&lt;0.001), 4.8% elevation of diastolic BP (DBP) (=0.001) in his wife. AH of a wife was associated with 5.5% elevation of SBP (&lt;0.001) and 5% elevation of DBP (=0.003) in a husband. Coefficient of correlation (r) of SBP levels between spouses was 0.09 in age group 20-39 years (=0.041) and 0.16 in age group 40-59 years (=0.002). For DBP in age group 20-39 years r=0.14 (=0.002), in age group 40-59 years r=0.10 (=0.042). In a prospective study in men and women we found higher SBP when AH was detected in a spouse during follow-up compared with individuals whose BP had been and remained normal (by 5.4%, =0.015) or those whose BP during this period decreased to normal level (by 17.5%; =0.006). Detection of new cases of AH in men - spouses of women with AH was higher than in man - cohabitants of wives without AH (53.8 and 37.3%, respectively, =0.028). Thus we found concordance of BP levels in spouses, which was conditioned by marital assortment as well as common environment and way of life.
authors.forename: I V
authors.initials: IV
authors.lastname: Dolgalev
authors.forename: N G
authors.initials: NG
authors.lastname: Brazovskaia
authors.forename: R S
authors.initials: RS
authors.lastname: Karpov
mesh_terms: D000328:Adult; D000367:Age Factors; D001794:Blood Pressure; D001795:Blood Pressure Determination / Q000379:methods; D015331:Cohort Studies; D005190:Family; D005192:Family Health / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000523:psychology; D008019:Life Style; D008297:Male; D008875:Middle Aged; D011897:Random Allocation; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology; D012737:Sex Factors; D018454:Spouses / Q000523:psychology / Q000706:statistics & numerical data