title: Coronary heart disease diagnosis bases on the change of different parts in treadmill exercise test ECG.
abstract: Summarize the value of the change of different parts in treadmill exercise test (TET) ECG to coronary heart disease (CHD) diagnosis. Four hundred and forty-five cases have been included in this investigation, which stayed in our hospital from January of 2006 to March of 2011 and underwent TET and coronary arteriography (CAG). The change of different parts in TET ECG in these patients had been retrospective summarized to determine its diagnosis value to CHD. (1) In the 445 cases of TET testers, 200 cases showed positive in TET with 150 cases of positive CAG, and 50 cases of negative CAG; 245 cases showed negative in TET with 206 cases of negative CAG, and 39 cases of positive CAG. The diagnosis sensitivity of CHD was 79.36% (150/189), the specificity was 80.47% (206/256), positive prediction value was 75.00% (150/200), negative prediction value was 84.08% (206/245), and false-positive rate was 25.00% (50/200) with prediction accuracy of 80.00% (356/445). (2) In the 200 cases with positive TET: 51 cases were in the limb lead group; 73 cases were in the chest lead group; and 76 cases were in the limb lead + chest lead group. There were 150 cases showing positive in CAG: 22 cases were in the limb lead group; 58 cases were in the chest lead group; and 70 cases were in the limb lead + chest lead group. The positive diagnosis rate of ST change in the chest lead was obviously higher than that of simple limb lead group (P < 0.05). (3) People with healthy coronary artery will have decreased amplitude of R wave while patients with coronary stenosis have elevated amplitude of R wave. (4) As for the T wave, the positive CAG had no statistical significance between normal T wave group and TET positive group (P > 0.05); CAG results had statistical significance between normal T wave group and TET negative group (P < 0.05). (5) Positive CAG results had no statistical significance between U-wave inversion group and TET positive group (P > 0.05); positive CAG results has statistical significance when TET negative group compared with U-wave inversion group or TET positive group (P < 0.05). TET is a relatively idea invasive diagnosis method for coronary disease, which can be utilized to evaluate the stage of CHD when integrating with the change of TET ECG.
authors.affiliation: Department of Cardiology, Aviation General Hospital, An Ding Men Wai Bei Yuan Road 3, Beijing, 100012, People's Republic of China, sunjianling2000@yahoo.com.cn.
authors.forename: Sun
authors.initials: S
authors.lastname: Jian-ling
authors.forename: Zhao
authors.initials: Z
authors.lastname: Ying
authors.forename: Gao
authors.initials: G
authors.lastname: Yu-lian
authors.forename: Xiong
authors.initials: X
authors.lastname: Li-juan
authors.forename: Guo
authors.initials: G
authors.lastname: Ji-hong
authors.forename: Li
authors.initials: L
authors.lastname: Xiao-ying
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis*; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies