title: Abnormal fusiform activation during emotional-face encoding assessed with functional magnetic resonance imaging.
abstract: This functional magnetic resonance imaging study shows that children and adults with bipolar disorder (BD), compared with healthy subjects, exhibit impaired memory for emotional faces and abnormal fusiform activation during encoding. Fusiform activation abnormalities in BD were correlated with mania severity and may therefore represent a trait and state BD biomarker.
authors.affiliation: Emotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA. adlemann@mail.nih.gov
authors.forename: Nancy E
authors.initials: NE
authors.lastname: Adleman
authors.forename: Reilly R
authors.initials: RR
authors.lastname: Kayser
authors.forename: Aviva K
authors.initials: AK
authors.lastname: Olsavsky
authors.forename: Brian L
authors.initials: BL
authors.lastname: Bones
authors.forename: Eli J
authors.initials: EJ
authors.lastname: Muhrer
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Fromm
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Pine
authors.forename: Carlos
authors.initials: C
authors.lastname: Zarate
authors.forename: Ellen
authors.initials: E
authors.lastname: Leibenluft
authors.forename: Melissa A
authors.initials: MA
authors.lastname: Brotman
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000704:Analysis of Variance; D001714:Bipolar Disorder / Q000150:complications* / Q000473:pathology*; D001921:Brain / Q000098:blood supply* / Q000254:growth & development / Q000473:pathology*; D002648:Child; D003072:Cognition Disorders / Q000209:etiology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D016014:Linear Models; D008279:Magnetic Resonance Imaging; D008297:Male; D008569:Memory Disorders / Q000209:etiology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D010100:Oxygen; D011569:Psychiatric Status Rating Scales; D055815:Young Adult
chemical_list: D010100:Oxygen
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