title: Prevalence, risk factors, and disease knowledge of chronic hepatitis B infection in Vietnamese Americans in California.
abstract: Our goal is to examine the prevalence, risk factors, and disease knowledge of chronic hepatitis B (CHB) among Vietnamese Americans in California. We also examined treatment eligibility and linkage to care among patients who tested positive for CHB. We enrolled 717 subjects from ten different hepatitis B virus (HBV) screening events in five locations from January 2009 to June 2010 in California. HBV status was determined by hepatitis B surface antigen (HBsAg) and antibody. Data were collected by a 36-question survey. A total of 99 patients (13.8 %) had positive HBsAg, especially those aged 31-40 years (23.6 %), and 177 (24.7 %) were still susceptible to HBV infection. A significant proportion of those who were HBsAg positive or still susceptible reported a history of HBV vaccination (10 and 20 %, respectively). Following adjustments for age and sex, significant predictors for HBsAg positivity were lack of healthcare coverage (OR=2.4, p=0.004), having a family history of CHB (OR=2.1, p=0.009), and prior occupational exposure (OR=3.0, p=0.007). Of those who tested positive, 13.3 % met criteria for antiviral therapy, but none had been initiated on treatment. HBV prevalence in Vietnamese Americans in California was high (13.8 %), especially in those between 31 and 40 years of age. Patient disease and treatment knowledge was poor, as were follow-up and management of those found to have CHB and/or have indication for antiviral therapy.
authors.affiliation: Pacific Health Foundation, San Jose, CA, USA.
authors.forename: Nghi B
authors.initials: NB
authors.lastname: Ha
authors.forename: Huy N
authors.initials: HN
authors.lastname: Trinh
authors.forename: Trang T
authors.initials: TT
authors.lastname: Nguyen
authors.forename: Truong-Sinh
authors.initials: TS
authors.lastname: Leduc
authors.forename: Christopher
authors.initials: C
authors.lastname: Bui
authors.forename: Nghiem B
authors.initials: NB
authors.lastname: Ha
authors.forename: Carrie R
authors.initials: CR
authors.lastname: Wong
authors.forename: Anh Thu
authors.initials: AT
authors.lastname: Tran
authors.forename: Mindie H
authors.initials: MH
authors.lastname: Nguyen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000998:Antiviral Agents / Q000008:administration & dosage; D001213:Asian; D002140:California; D003430:Cross-Sectional Studies; D005260:Female; D007722:Health Knowledge, Attitudes, Practice / Q000208:ethnology*; D057220:Health Literacy; D006306:Health Surveys; D017325:Hepatitis B Vaccines / Q000008:administration & dosage; D019694:Hepatitis B, Chronic / Q000453:epidemiology / Q000208:ethnology* / Q000517:prevention & control / Q000635:transmission; D006801:Humans; D019458:Insurance Coverage; D008297:Male; D008403:Mass Screening; D017057:Medically Uninsured / Q000208:ethnology; D008875:Middle Aged; D012307:Risk Factors; D014744:Vietnam / Q000208:ethnology; D055815:Young Adult
chemical_list: D000998:Antiviral Agents; D017325:Hepatitis B Vaccines
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