title: Accuracy and usefulness of the AVOXimeter 4000 as routine analysis of carboxyhemoglobin.
abstract: The measurement of blood carboxyhemoglobin (CO-Hb) is important to determine the cause of death. The AVOXimeter 4000 (AVOX), a portable CO-oximeter, has the advantages of a low purchase price and operating cost, ease of operation, and rapid results. Little information is available on the usefulness of AVOX in the forensic sample, and the previous study investigated only six samples. Therefore, in this study, we confirmed the usefulness of the AVOX through a comparison of its results with data previously obtained using the double wavelength spectrophotometric method in autopsies. Regression analysis was performed between CO-Hb levels measured by the AVOX and those measured by the conventional double wavelength spectrophotometric method in postmortem blood samples: a significant correlation was observed. This study suggests the usefulness of the AVOX to analyze postmortem blood, and the AVOX is suitable for routine forensic analysis and can be applied at the crime scene.
authors.affiliation: Department of Legal Medicine, Shimane University School of Medicine, 89-1 Enya, Izumo Shimane, 693-8501, Japan.
authors.forename: Junko
authors.initials: J
authors.lastname: Fujihara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kinoshita
authors.forename: Naoko
authors.initials: N
authors.lastname: Tanaka
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Yasuda
authors.forename: Haruo
authors.initials: H
authors.lastname: Takeshita
mesh_terms: D002249:Carbon Monoxide Poisoning / Q000175:diagnosis*; D002263:Carboxyhemoglobin / Q000032:analysis*; D005554:Forensic Medicine; D006801:Humans; D010092:Oximetry / Q000295:instrumentation*; D012044:Regression Analysis; D015203:Reproducibility of Results; D013053:Spectrophotometry
chemical_list: D002263:Carboxyhemoglobin
keywords: AVOXimeter 4000; blood; carbon monoxide poisoning; carboxyhemoglobin; forensic science; usefulness