title: The use of iloprost in the treatment of 'out of proportion' pulmonary hypertension in chronic obstructive pulmonary disease.
abstract: METHODS
  Pulmonary hypertension secondary to respiratory disease most often occurs as a complication of chronic obstructive pulmonary disease, which currently constitutes one of the leading causes of death. Some patients with hypoxaemia reveal "out of proportion" pulmonary hypertension with inappropriate increase of pulmonary artery pressure. Iloprost, analogue of prostacyclin, dilates systemic vessels and pulmonary vessels in particular if administered by inhalation. It appears to be important, life-saving, complementary therapy. However, there is no evidence for its routine use in out of proportion arterial pulmonary hypertension. This case study presents a 44-year old man with chronic obstructive pulmonary disease and "out of proportion" pulmonary hypertension. We present the results of his treatment with iloprost.
  
  
  CONCLUSIONS
  In a patient with "out of proportion" pulmonary hypertension due to chronic obstructive pulmonary disease, inhaled iloprost led to improvement in clinical status and echocardiographic parameters, including a reduction of right ventricular systolic pressure.
authors.affiliation: 2nd Department of Cardiology, Medical University of Silesia, Katowice ul. Ziołowa 45/47, 40-635 Katowice, Poland. blasota@poczta.onet.pl
authors.forename: Bartosz
authors.initials: B
authors.lastname: Lasota
authors.forename: Szymon
authors.initials: S
authors.lastname: Skoczyński
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Mizia-Stec
authors.forename: Władysław
authors.initials: W
authors.lastname: Pierzchała
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D016285:Iloprost / Q000627:therapeutic use*; D008297:Male; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications*; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D014665:Vasodilator Agents; D016285:Iloprost
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