title: Multicentric reticulohistiocytosis presenting with papulonodular skin lesions and arthritis mutilans.
abstract: Multicentric reticulohistiocytosis is a rare multisystem disorder of unknown etiology that is characterized by erosive polyarthritis and papulonodular lesions on the skin, mucous membranes, and internal organs. We report the case of a 54-year-old female who was misdiagnosed as having rheumatoid arthritis and underwent numerous joint replacement surgeries for progressively destructive arthritis in her hands, shoulders, hips, and knees. The patient finally received a diagnosis of multicentric reticulohistiocytosis after histopathological examination of the patient's left knee arthroplasty which revealed a diffuse histiocytic infiltrate, multinucleated giant cells, and finely granulated eosinophilic cytoplasm with a ground-glass appearance.
authors.affiliation: Department of Internal Medicine, Saint Joseph Hospital, 2900 N. Lake Shore, Chicago, IL 60657, USA.
authors.forename: Raya
authors.initials: R
authors.lastname: Saba
authors.forename: Shawn G
authors.initials: SG
authors.lastname: Kwatra
authors.forename: Bishwas
authors.initials: B
authors.lastname: Upadhyay
authors.forename: Aibek E
authors.initials: AE
authors.lastname: Mirrakhimov
authors.forename: Farah N
authors.initials: FN
authors.lastname: Khan
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