title: New hypothesis on the origin of metastases.
abstract: A new hypothesis for the origin of metastases is presented. It assumes that a cancer-transformed gene in a primary tumour is incorporated in its identical form via a virus-vector function into biologically potent recipient cells in other organs, such as stem cells, multipotent cells or cells in an early phase of division. The origin of metastases may thus possibly occur via a genetic pathway.
authors.affiliation: nschischmanov@hotmail.com
authors.forename: Nicola
authors.initials: N
authors.lastname: Schischmanov
mesh_terms: D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000235:genetics* / Q000473:pathology*; D015972:Gene Expression Regulation, Neoplastic; D020022:Genetic Predisposition to Disease; D006801:Humans; D008954:Models, Biological; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000235:genetics* / Q000473:pathology*; D014411:Neoplastic Stem Cells / Q000473:pathology*; D010641:Phenotype
references.citation: Lakartidningen. 1993 Jun 16;90(24):2311-2
references.pmid: 8391101
references.citation: Breast Cancer. 1995 Apr 30;2(1):9-18
references.pmid: 11091527
references.citation: Biochem Med (Zagreb). 2011;21(3):264-75
references.pmid: 22420240
references.citation: Lakartidningen. 2000 Jul 12;97(28-29):3260-4
references.pmid: 10997012
references.citation: Lakartidningen. 2001 Jun 13;98(24):2931-4
references.pmid: 11449899
references.citation: N Engl J Med. 2011 May 12;364(19):1795-806
references.pmid: 21561345
references.citation: Acta Oncol. 1996;35 Suppl 8:3-6
references.pmid: 9073042
references.citation: Acta Oncol. 1993;32(1):3-8
references.pmid: 8466761