title: Modulation of untruthful responses with non-invasive brain stimulation.
abstract: Deceptive abilities have long been studied in relation to personality traits. More recently, studies explored the neural substrates associated with deceptive skills suggesting a critical role of the prefrontal cortex. Here we investigated whether non-invasive brain stimulation over the dorsolateral prefrontal cortex (DLPFC) could modulate generation of untruthful responses about subject's personal life across contexts (i.e., deceiving on guilt-free questions on daily activities; generating previously memorized lies about past experience; and producing spontaneous lies about past experience), as well as across modality responses (verbal and motor responses). Results reveal that real, but not sham, transcranial direct current stimulation (tDCS) over the DLPFC can reduce response latency for untruthful over truthful answers across contexts and modality responses. Also, contexts of lies seem to incur a different hemispheric laterality. These findings add up to previous studies demonstrating that it is possible to modulate some processes involved in generation of untruthful answers by applying non-invasive brain stimulation over the DLPFC and extend these findings by showing a differential hemispheric contribution of DLPFCs according to contexts.
authors.affiliation: Berenson-Allen Center for Non-invasive Brain Stimulation, Harvard Medical School and Beth Israel Deaconess Medical Center Boston, MA, USA ; Laboratory of Canada Research Chair in Cognitive Neuroplasticity, Centre Interdisciplinaire de recherche en réadaptation et intégration sociale, Centre de Recherche de l'Institut Universitaire en Santé Mentale de Québec, Medical School, Laval University Quebec City, Canada.
authors.forename: Shirley
authors.initials: S
authors.lastname: Fecteau
authors.forename: Paulo
authors.initials: P
authors.lastname: Boggio
authors.forename: Felipe
authors.initials: F
authors.lastname: Fregni
authors.forename: Alvaro
authors.initials: A
authors.lastname: Pascual-Leone
keywords: brain stimulation; deception; dorsolateral prefrontal cortex; verbal communication
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