title: The effects of treatment on itch in atopic dermatitis.
abstract: Pruritus causes significant impairment in the quality of life of patients suffering from atopic dermatitis. Treatments for itch in atopic dermatitis range from simple avoidance of pruritus triggers to more complicated systemic therapy. Several treatments aim to target specific mediators of itch in atopic dermatitis, whereas others improve pruritus by reducing inflammation. Currently the most effective treatments for atopic dermatitis-associated itch are primarily topical or systemic anti-inflammatory agents. Better management of pruritus in atopic dermatitis is an important goal and necessitates the development of novel targeted treatments as well as efficient use of current therapies.
authors.affiliation: Department of Dermatology, Oregon Health & Science University, Portland, Oregon 97239-4501, USA.
authors.forename: Kevin B
authors.initials: KB
authors.lastname: Yarbrough
authors.forename: Kristin J
authors.initials: KJ
authors.lastname: Neuhaus
authors.forename: Eric L
authors.initials: EL
authors.lastname: Simpson
mesh_terms: D000279:Administration, Cutaneous; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D003876:Dermatitis, Atopic / Q000503:physiopathology / Q000628:therapy*; D015195:Drug Design; D006801:Humans; D007249:Inflammation / Q000209:etiology / Q000628:therapy; D011537:Pruritus / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D011788:Quality of Life
chemical_list: D000893:Anti-Inflammatory Agents
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