title: Unusual case of cavitary lung metastasis from squamous cell carcinoma of the uterine cervix.
abstract: Spontaneous excavation of primary lung cancer is common; however cavitation of metastatic lung lesions is rare and usually confused with benign lesions. In Moroccan context tuberculosis is the first suspected diagnosis of lung excavations. We report a rare case of cavitary lung metastasis of a uterine cervix cancer, treated initially as tuberculosis. A 40-year old non-smoking woman with a known history of squamous cell carcinoma of the uterine cervix since August 2005; presented on September 2008 with right chest pain without fever, hemoptysis or weight loss. CT scan showed a thin walled cavity. Empirical Antibiotic therapy was conducted 15 days with poor outcome. Then antibacillary treatment was started with no proof of mycobacterial infection. A month later, the patient presented with gynecological bleeding and a pneumothorax. Bronchoscopy with transbronchial biopsy of the cavitary mass was performed. Pathology demonstrated a metastatic squamous cell carcinoma. Pelvic examination and MRI showed a subsequent local cervix recurrence. Patient underwent 3 courses of systemic chemotherapy. She died on June 2009 due to progressive disease. Even cavitary lung metastases are rare and benign differential diagnosis are more common, clinician should be careful in neoplastic context and investigation should be done to eliminate a recurrence.
authors.affiliation: Department of medical oncology, National Institute of Oncology, Rabat, Morocco.
authors.forename: Soundouss
authors.initials: S
authors.lastname: Raissouni
authors.forename: Rais
authors.initials: R
authors.lastname: Ghizlane
authors.forename: Houda
authors.initials: H
authors.lastname: Mouzount
authors.forename: Kharmoum
authors.initials: K
authors.lastname: Saoussane
authors.forename: Setti
authors.initials: S
authors.lastname: Khadija
authors.forename: Fouad
authors.initials: F
authors.lastname: Zouaidia
authors.forename: Rachida
authors.initials: R
authors.lastname: Latib
authors.forename: Hind
authors.initials: H
authors.lastname: Mrabti
authors.forename: Hassan
authors.initials: H
authors.lastname: Errihani
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000556:secondary*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary*; D014594:Uterine Neoplasms / Q000473:pathology*
keywords: cavitary lung metastasis; squamous cell carcinoma; uterine cervix
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