title: Chondroblastoma and chondromyxoid fibroma.
abstract: Chondroblastoma and chondromyxoid fibroma are benign but locally aggressive bone tumors. Chondroblastoma, a destructive lesion with a thin radiodense border, is usually seen in the epiphysis of long bones. Chondromyxoid fibroma presents as a bigger, lucent, loculated lesion with a sharp sclerotic margin in the metaphysis of long bones. Although uncommon, these tumors can be challenging to manage. They share similarities in pathology that could be related to their histogenic similarity. Very rarely, chondroblastoma may lead to lung metastases; however, the mechanism is not well understood.
authors.affiliation: Department of Orthopaedic Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
authors.forename: Camila B R
authors.initials: CB
authors.lastname: De Mattos
authors.forename: Chanika
authors.initials: C
authors.lastname: Angsanuntsukh
authors.forename: Alexandre
authors.initials: A
authors.lastname: Arkader
authors.forename: John P
authors.initials: JP
authors.lastname: Dormans
mesh_terms: D001859:Bone Neoplasms / Q000175:diagnosis / Q000601:surgery; D002804:Chondroblastoma / Q000175:diagnosis / Q000601:surgery; D005350:Fibroma / Q000175:diagnosis / Q000601:surgery; D006801:Humans