title: The antibacterial shield of the human urinary tract.
abstract: Antibacterial peptides and proteins maintain the sterility of the human urinary tract. A broad-spectrum antimicrobial protein, ribonuclease 7 (RNase 7), previously discovered to play a role in controlling the growth of bacteria on human skin, has now been shown to have an important antibacterial function in the human urinary tract.
authors.affiliation: Georgetown Transplant Institute, Georgetown University School of Medicine, Washington, DC 20007, USA. maz5@georgetown.edu
authors.forename: Michael
authors.initials: M
authors.lastname: Zasloff
mesh_terms: D006801:Humans; D007668:Kidney / Q000201:enzymology*; D011704:Pyelonephritis / Q000201:enzymology*; D012260:Ribonucleases / Q000378:metabolism*; D014552:Urinary Tract Infections / Q000201:enzymology*
chemical_list: D012260:Ribonucleases; C470000:Ribonuclease 7