title: Psychological differences between early- and late-onset psoriasis: a study of personality traits, anxiety and depression in psoriasis.
abstract: BACKGROUND
  Onset of psoriasis may occur at any age. Early negative experiences often influence personality development, and may lead to physical disease, anxiety and depression in adulthood. Knowledge about onset of psoriasis and psychopathology is limited.
  
  
  OBJECTIVE
  To examine whether patients with early-onset psoriasis differ psychologically from patients with late-onset psoriasis, regarding personality traits, anxiety and depression.
  
  
  METHODS
  A descriptive cross-sectional study was conducted among 101 consecutively recruited outpatients with psoriasis. A psychosocial interview was performed followed by self-assessment of validated questionnaires: Swedish Universities Scales of Personality (SSP), Spielberger State-Trait Anxiety Inventory and Beck Depression Inventory. Psoriasis severity was assessed by the Psoriasis Area and Severity Index.
  
  
  RESULTS
  Patients with early-onset psoriasis (age < 20 years) were significantly more anxious and depressed than patients with late-onset psoriasis. In multiple linear regression models, younger age at onset of psoriasis was a significant determinant of higher scores of four personality traits: SSP-embitterment, -trait irritability, -mistrust and -verbal trait aggression.
  
  
  CONCLUSIONS
  Our results indicate that early detection of psychological vulnerability when treating children and adolescents with psoriasis seems to be of great importance. Traits of psychological vulnerability and pessimistic personality traits were found to be significantly associated with the early onset of psoriasis, but not with disease duration in this study. These traits may be seen as a consequence of psoriasis, and/or as individual traits modulating and impairing clinical course and efforts to cope with psoriasis.
authors.affiliation: Department of Dermatology, University of Lund, Malmö, Sweden. charlotta.remrod@med.lu.se
authors.forename: C
authors.initials: C
authors.lastname: Remröd
authors.forename: K
authors.initials: K
authors.lastname: Sjöström
authors.forename: A
authors.initials: A
authors.lastname: Svensson
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D000368:Aged; D001007:Anxiety / Q000209:etiology*; D003430:Cross-Sectional Studies; D003863:Depression / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010551:Personality; D011565:Psoriasis / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D055815:Young Adult
keywords: anxiety; depression; early onset psoriasis; personality; psoriasis