title: Xylomexicanins C and D, new mexicanolide-type limonoids from Xylocarpus granatum.
abstract: Two new limonoids, named xylomexicanins C and D, were isolated from a dichloromethane extract of the seeds of Xylocarpus granatum cultivated in Hainan, China, and their structures were elucidated on the basis of one- and two-dimensional NMR (including 1H, 13C-NMR, DEPT, 1H-1H COSY, HSQC, HMBC, and NOESY) and confirmed by high-resolution mass spectrometry. Xylomexicanin C exhibited antiproliferative activity against human breast carcinoma cells (KT).
authors.affiliation: School of Pharmaceutical Sciences, Hebei Key Laboratory of Forensic Medicine, Department of Forensic Medicine, Hebei Medical University, Hebei Province, China.
authors.forename: Yi-Bing
authors.initials: YB
authors.lastname: Wu
authors.forename: Zhi-Yu
authors.initials: ZY
authors.lastname: Ni
authors.forename: Chang-Hong
authors.initials: CH
authors.lastname: Huo
authors.forename: Jian
authors.initials: J
authors.lastname: Su
authors.forename: Mei
authors.initials: M
authors.lastname: Dong
authors.forename: Françoise
authors.initials: F
authors.lastname: Sauriol
authors.forename: Qing-Wen
authors.initials: QW
authors.lastname: Shi
authors.forename: Yu-Cheng
authors.initials: YC
authors.lastname: Gu
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Kiyota
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D045744:Cell Line, Tumor; D006801:Humans; D036701:Limonins / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D029582:Meliaceae / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D036701:Limonins; C554989:mexicanolide; C584525:xylomexicanin C; C584526:xylomexicanin D