title: The effects of visual control and distance in modulating peripersonal spatial representation.
abstract: In the presence of vision, finalized motor acts can trigger spatial remapping, i.e., reference frames transformations to allow for a better interaction with targets. However, it is yet unclear how the peripersonal space is encoded and remapped depending on the availability of visual feedback and on the target position within the individual's reachable space, and which cerebral areas subserve such processes. Here, functional magnetic resonance imaging (fMRI) was used to examine neural activity while healthy young participants performed reach-to-grasp movements with and without visual feedback and at different distances of the target from the effector (near to the hand-about 15 cm from the starting position-vs. far from the hand-about 30 cm from the starting position). Brain response in the superior parietal lobule bilaterally, in the right dorsal premotor cortex, and in the anterior part of the right inferior parietal lobule was significantly greater during visually-guided grasping of targets located at the far distance compared to grasping of targets located near to the hand. In the absence of visual feedback, the inferior parietal lobule exhibited a greater activity during grasping of targets at the near compared to the far distance. Results suggest that in the presence of visual feedback, a visuo-motor circuit integrates visuo-motor information when targets are located farther away. Conversely in the absence of visual feedback, encoding of space may demand multisensory remapping processes, even in the case of more proximal targets.
authors.affiliation: Laboratory of Clinical Biochemistry and Molecular Biology, University of Pisa Medical School, Pisa, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Renzi
authors.forename: Emiliano
authors.initials: E
authors.lastname: Ricciardi
authors.forename: Daniela
authors.initials: D
authors.lastname: Bonino
authors.forename: Giacomo
authors.initials: G
authors.lastname: Handjaras
authors.forename: Tomaso
authors.initials: T
authors.lastname: Vecchi
authors.forename: Pietro
authors.initials: P
authors.lastname: Pietrini
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology; D056228:Feedback, Sensory / Q000502:physiology; D005260:Female; D018737:Hand Strength / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009068:Movement / Q000502:physiology; D009415:Nerve Net / Q000502:physiology; D010550:Personal Space; D014796:Visual Perception / Q000502:physiology*
references.citation: Curr Opin Neurobiol. 2005 Dec;15(6):626-31
references.pmid: 16271458
references.citation: Annu Rev Neurosci. 2002;25:189-220
references.pmid: 12052908
references.citation: Neuroimage. 2011 Feb 1;54(3):2401-11
references.pmid: 20932912
references.citation: Nature. 2002 Apr 11;416(6881):632-6
references.pmid: 11948351
references.citation: J Neurophysiol. 2004 Apr;91(4):1648-60
references.pmid: 14586035
references.citation: Neuropsychologia. 1997 Dec;35(12):1577-82
references.pmid: 9460728
references.citation: Conscious Cogn. 2007 Sep;16(3):667-83
references.pmid: 17728152
references.citation: Neurology. 2005 Dec 13;65(11):1754-8
references.pmid: 16344519
references.citation: Brain. 2007 Feb;130(Pt 2):431-41
references.pmid: 17008330
references.citation: J Neurosci. 2011 Jun 15;31(24):9023-31
references.pmid: 21677185
references.citation: J Neurophysiol. 2006 Jul;96(1):352-62
references.pmid: 16571731
references.citation: Int J Neurosci. 1991 Dec;61(3-4):229-39
references.pmid: 1824384
references.citation: J Neurophysiol. 2007 Jan;97(1):188-99
references.pmid: 16928798
references.citation: Neuroimage. 2001 Dec;14(6):1469-75
references.pmid: 11707103
references.citation: J Neurosci. 2007 Oct 31;27(44):11877-87
references.pmid: 17978028
references.citation: Exp Brain Res. 1993;94(3):471-7
references.pmid: 8359261
references.citation: J Neurophysiol. 2000 Jan;83(1):528-36
references.pmid: 10634893
references.citation: Exp Brain Res. 1993;96(1):152-62
references.pmid: 8243577
references.citation: Exp Brain Res. 2002 Dec;147(4):426-36
references.pmid: 12444474
references.citation: J Neurosci. 2007 Jan 24;27(4):731-40
references.pmid: 17251412
references.citation: Cortex. 2007 Apr;43(3):397-410
references.pmid: 17533763
references.citation: Brain Topogr. 2009 May;21(3-4):252-60
references.pmid: 19387818
references.citation: Neuroimage. 2006 Jan 1;29(1):54-66
references.pmid: 16099175
references.citation: Cereb Cortex. 2001 Jun;11(6):528-44
references.pmid: 11375914
references.citation: J Cogn Neurosci. 2004 Nov;16(9):1517-35
references.pmid: 15601516
references.citation: Exp Brain Res. 2006 Mar;169(4):473-81
references.pmid: 16292638
references.citation: J Neurosci. 2012 Oct 17;32(42):14573-82
references.pmid: 23077043
references.citation: Exp Brain Res. 2003 Nov;153(2):180-9
references.pmid: 12961051
references.citation: J Mot Behav. 1986 Sep;18(3):245-60
references.pmid: 15138146
references.citation: Nat Rev Neurosci. 2002 Sep;3(9):741-7
references.pmid: 12209122
references.citation: J Neurophysiol. 2000 Apr;83(4):2374-91
references.pmid: 10758140
references.citation: J Exp Psychol Hum Percept Perform. 2005 Oct;31(5):880-8
references.pmid: 16262485
references.citation: Exp Brain Res. 2001 Nov;141(2):166-73
references.pmid: 11713628
references.citation: Neuropsychologia. 2010 Feb;48(3):796-802
references.pmid: 19837102
references.citation: J Neurophysiol. 2004 Oct;92(4):1990-2002
references.pmid: 15163668
references.citation: Neurology. 1998 May;50(5):1253-9
references.pmid: 9595971
references.citation: Comput Biomed Res. 1996 Jun;29(3):162-73
references.pmid: 8812068
references.citation: Exp Brain Res. 1987;67(1):220-4
references.pmid: 3622679
references.citation: Biol Cybern. 1992;67(4):347-60
references.pmid: 1515513
references.citation: Exp Brain Res. 2010 Nov;207(1-2):95-103
references.pmid: 20931177
references.citation: Neuroreport. 2009 Jul 1;20(10):913-7
references.pmid: 19512951
references.citation: Neuroimage. 2009 Feb 1;44(3):1032-40
references.pmid: 18951984
references.citation: J Neurosci. 2010 Aug 4;30(31):10306-23
references.pmid: 20685975
references.citation: Neuropsychologia. 2005;43(2):238-48
references.pmid: 15707908
references.citation: J Neurophysiol. 2011 Feb;105(2):910-22
references.pmid: 21148091
references.citation: Neuron. 2005 Aug 4;47(3):457-70
references.pmid: 16055068
references.citation: Neuroreport. 1996 Oct 2;7(14):2325-30
references.pmid: 8951846
references.citation: Exp Brain Res. 2007 Aug;181(3):447-60
references.pmid: 17476491
references.citation: Exp Brain Res. 1991;86(1):199-208
references.pmid: 1756790
references.citation: Exp Brain Res. 2010 Aug;204(4):475-91
references.pmid: 20532487
references.citation: Neuroscientist. 2007 Feb;13(1):22-7
references.pmid: 17229972
references.citation: J Neurophysiol. 2005 Feb;93(2):954-62
references.pmid: 15356184