title: Reply to commentaries.
authors.affiliation: Department of Psychiatry & Behavioral Sciences, University of Washington, Seattle, WA, USA.
authors.forename: Mark D
authors.initials: MD
authors.lastname: Sullivan
authors.forename: Alex
authors.initials: A
authors.lastname: Cahana
authors.forename: Stuart
authors.initials: S
authors.lastname: Derbyshire
authors.forename: John D
authors.initials: JD
authors.lastname: Loeser
mesh_terms: D001921:Brain / Q000473:pathology*; D001927:Brain Diseases; D059350:Chronic Pain / Q000209:etiology*; D006801:Humans; D059906:Neuroimaging; D010146:Pain; D010147:Pain Measurement / Q000379:methods*