title: Heart failure therapy in patients with coronary artery disease.
abstract: Heart failure and coronary artery disease share many risk factors. Coronary artery disease often pre-dates the development of heart failure with reduced ejection fraction. A diagnosis of heart failure should be considered in any patient with a history of coronary artery disease who presents with breathlessness, ankle oedema or fatigue. Several therapies, such as renin-angiotensin antagonists and B blockers, have been proven to improve survival in patients with heart failure with reduced ejection fraction but evidence for effectiveness in heart failure with preserved ejection fraction is lacking. The management of heart failure and coronary artery disease overlaps considerably but can also be conflicting. Optimal risk factor management is key to preventing progression to heart failure in patients with coronary artery disease.
authors.affiliation: Primary Care Clinical Sciences, University of Birmingham, Edgbaston B15 2TT, United Kingdom.
authors.forename: Clare J
authors.initials: CJ
authors.lastname: Taylor
authors.forename: F D Richard
authors.initials: FD
authors.lastname: Hobbs
mesh_terms: D002317:Cardiovascular Agents / Q000627:therapeutic use; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D017147:Defibrillators, Implantable; D006333:Heart Failure / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000628:therapy*; D006801:Humans
chemical_list: D002317:Cardiovascular Agents