title: Optical quality comparison of conventional and hole-visian implantable collamer lens at different degrees of decentering.
abstract: OBJECTIVE
  To compare the optical quality of implantable Collamer lens (ICL) with and without central hole (Hole ICL and conventional ICL) at different degrees of decentering.
  
  
  METHODS
  Experimental laboratory investigation.
  
  
  METHODS
  Wavefront aberrations of the -3, -6, and -12 diopter (D) V4b and -3, -6, and -12 D V4c ICLs were measured in 3 conditions-centered and decentered 0.3 and 0.6 mm-at 3-mm and 4.5-mm pupils. The root mean square of total higher order aberrations, trefoil, coma, tetrafoil, secondary astigmatism, and spherical aberration were evaluated. In addition, point spread function and simulated retinal images of ICLs were calculated from the wavefront aberrations for each ICL and all conditions of decentering at 4.5-mm pupil.
  
  
  RESULTS
  No statistically significant differences in any Zernike coefficient terms evaluated were found between conventional and Hole ICLs for any ICL powers and pupils evaluated (P > .05). We could not appreciate differences in the point spread function images and in simulated retinal images. Regarding the effect of the ICL decentration, coma aberration increased significantly with ICL decentration (P < .05), although these differences were not visible in the point spread function images and simulated retinal images. The ICL decentration was affected in the same manner on the conventional and Hole ICLs.
  
  
  CONCLUSIONS
  The outcomes showed good and comparable optical quality of the conventional and Hole ICLs for all ICL powers evaluated. Despite that coma aberration increased with ICL decentering, these values were clinically negligible and did not have a significant effect on the simulated visual performance.
authors.affiliation: Optics Research Group, Optics Department, Faculty of Physics, Universidad de Valencia, Valencia, Spain. cari.perez@uv.es
authors.forename: Cari
authors.initials: C
authors.lastname: Pérez-Vives
authors.forename: Teresa
authors.initials: T
authors.lastname: Ferrer-Blasco
authors.forename: David
authors.initials: D
authors.lastname: Madrid-Costa
authors.forename: Santiago
authors.initials: S
authors.lastname: García-Lázaro
authors.forename: Robert
authors.initials: R
authors.lastname: Montés-Micó
mesh_terms: D060437:Artificial Lens Implant Migration / Q000209:etiology / Q000503:physiopathology*; D001251:Astigmatism / Q000175:diagnosis; D057108:Corneal Wavefront Aberration / Q000175:diagnosis; D006801:Humans; D066298:In Vitro Techniques; D019654:Lens Implantation, Intraocular; D008962:Models, Theoretical; D055095:Optics and Photonics; D054120:Phakic Intraocular Lenses; D011474:Prosthesis Design; D054140:Refractive Surgical Procedures; D012160:Retina / Q000502:physiology