title: [A case of tacrolimus plus intensive LCAP therapy combination for refractory ulcerative colitis].
abstract: A 30-year-old woman was referred to our hospital with recurrent refractory ulcerative colitis. She also suffered from avascular necrosis of the left femoral head caused by steroid use. We had expected that tacrolimus would contribute to remission, but effects remained insufficient even after 16 days of treatment. Intensive leukocytapheresis (LCAP) therapy was added to tacrolimus therapy, and this combination achieved remission. Tacrolimus plus intensive LCAP combination therapy appears useful in treating refractory ulcerative colitis.
authors.affiliation: Department of Gastroenterology, National Hospital Organization Nagasaki Medical Center. matsuayak@yahoo.co.jp
authors.forename: Ayako
authors.initials: A
authors.lastname: Matsumoto
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yajima
authors.forename: Tomoya
authors.initials: T
authors.lastname: Murata
authors.forename: Kousuke
authors.initials: K
authors.lastname: Gotou
authors.forename: Kenta
authors.initials: K
authors.lastname: Okamoto
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Nishiyama
mesh_terms: D000328:Adult; D003093:Colitis, Ulcerative / Q000628:therapy*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007937:Leukapheresis / Q000379:methods*; D016559:Tacrolimus / Q000627:therapeutic use*
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus