title: Clinical, radiographic and histologic analysis of the effects of pulp capping materials used in pulpotomies of human primary teeth.
abstract: OBJECTIVE
  To compare the clinical, radiographic and histological responses of the pulp to mineral trioxide aggregate (MTA), calcium hydroxide (CH) and Portland cement (PC) when used as a pulpotomy agent in human primary teeth.
  
  
  METHODS
  Forty-five mandibular primary molar teeth were randomly assigned to CH, MTA or PC groups and treated by pulpotomy technique.
  
  
  METHODS
  The teeth were treated by conventional pulpotomy technique, differing only in the capping material for each group. Clinical and radiographic evaluations were recorded at 6-, 12- and 24-month follow-up. Teeth in the regular exfoliation period were further processed for histologic analysis.
  
  
  METHODS
  Data were tested using parametric tests at a significance level of 5 %. The histological results were expressed descriptively.
  
  
  RESULTS
  Clinically and radiographically, the MTA and PC groups showed 100 % success rates at 6, 12 and 24 months. In CH group, several teeth presented clinical and radiographic failures detected throughout the follow-up period, and internal resorption was a frequent radiographic finding. Histologic analysis revealed the presence of dentine-like mineralised material deposition obliterating the root canal in the PC and MTA groups. CH group presented, in most of the sections, necrotic areas in the root canals.
  
  
  CONCLUSIONS
  MTA and PC may serve as effective materials for pulpotomies of primary teeth as compared to CH. Although our results are very encouraging, further studies and longer follow-up assessments are needed in order to determine the safe clinical indication of Portland cement.
authors.affiliation: Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Octávio Pinheiro Brisolla, 9-75, Bauru, São Paulo, 17012-901, Brazil, marchini@usp.br.
authors.forename: T M
authors.initials: TM
authors.lastname: Oliveira
authors.forename: A B S
authors.initials: AB
authors.lastname: Moretti
authors.forename: V T
authors.initials: VT
authors.lastname: Sakai
authors.forename: N
authors.initials: N
authors.lastname: Lourenço Neto
authors.forename: C F
authors.initials: CF
authors.lastname: Santos
authors.forename: M A A M
authors.initials: MA
authors.lastname: Machado
authors.forename: R C C
authors.initials: RC
authors.lastname: Abdo
mesh_terms: D002126:Calcium Hydroxide / Q000627:therapeutic use; D003785:Dental Pulp Capping; D006801:Humans; D008963:Molar; D011672:Pulpotomy; D014094:Tooth, Deciduous
chemical_list: D002126:Calcium Hydroxide
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