title: Clinical characteristics and treatment outcomes of patients with unresectable cholangiocarcinoma in Thailand: are there differences dependent on stent type?
abstract: Cholangiocarcinoma, though very rare in Western countries, is one of the commonest liver malignancies in Southeast Asia, especially in Thailand. More than half of the patients present with advanced stage disease. Given the poor treatment outcomes of adjuvant therapeutic options, many patients undergo only biliary drainage for palliative treatment. Clinical characteristics and treatment outcomes after biliary stenting were here analyzed for a total of 224 unresectable cholangiocarcinoma cases, 58.9% in men. The mean age was 61.5 years. Hilar involvement was the most common location. The patients underwent biliary drainage using plastic and metallic stents equally, early stent occlusion being encountered in 21.4% and 10.7%, respectively. The median survival time was 4.93 months for patients who received plastic and 5.87 months for patients who received metallic stents.
authors.affiliation: Siriraj GI Endoscopy Center, Division of Gastroenterology, Siriraj Hospital, Mahidol University, Bangkok, Thailand. kaiyjr@gmail.com
authors.forename: Varayu
authors.initials: V
authors.lastname: Prachayakul
authors.forename: Suthasinee
authors.initials: S
authors.lastname: Chaisayan
authors.forename: Pitulak
authors.initials: P
authors.lastname: Aswakul
authors.forename: Morakod
authors.initials: M
authors.lastname: Deesomsak
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001650:Bile Duct Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy*; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000150:complications / Q000473:pathology / Q000628:therapy*; D002760:Cholangiopancreatography, Endoscopic Retrograde; D004322:Drainage / Q000295:instrumentation; D004867:Equipment Design; D005260:Female; D006801:Humans; D041781:Jaundice, Obstructive / Q000209:etiology; D008297:Male; D008670:Metals; D008875:Middle Aged; D009367:Neoplasm Staging; D010969:Plastics; D012189:Retrospective Studies; D015607:Stents / Q000009:adverse effects; D013785:Thailand; D015431:Weight Loss
chemical_list: D008670:Metals; D010969:Plastics