title: Treatment of E. boehmi infection in a mixed-breed dog using milbemycin oxime.
abstract: Numerous bipolar plugged capillarid eggs were detected on a routine centrifugal fecal flotation examination of a 2 yr old castrated male boxer-Chinese shar pei mixed-breed. The eggs were identified as Eucoleus boehmi (E. boehmi), the nasal capillarid, based on size and shell wall surface morphology. The dog had a history of chronic sneezing (> 5 times/day) and intermittent postexercise nasal discharge. Currently, there are no anthelmintics approved for use in dogs for the treatment of E. boehmi. Treatment of the dog with 0.5-1 mg/kg milbemycin oxime was ineffective, but treatment with 2 mg/kg milbemycin oxime resulted in negative fecal examinations 7-28 days and 5 mo posttreatment. The dog's postexertion nasal discharge greatly lessened, and the sneezing behavior improved (it was only noted 2-3 times/wk), but neither the discharge nor sneezing completely resolved following the anthelmintic treatments. Use of milbemycin oxime at an increased dose (2 mg/kg) appeared to be an effective treatment against E. boehmi infection in this dog based on clinical response and the cessation of fecal egg shedding.
authors.affiliation: Department of Pathology and Microbiology, Atlantic Veterinary College, Charlottetown, PEI, Canada. conboy@upei.ca
authors.forename: Gary
authors.initials: G
authors.lastname: Conboy
authors.forename: Tonya
authors.initials: T
authors.lastname: Stewart
authors.forename: Susan
authors.initials: S
authors.lastname: O'Brien
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D002195:Capillaria / Q000302:isolation & purification; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D017189:Enoplida Infections / Q000188:drug therapy / Q000662:veterinary*; D005243:Feces / Q000469:parasitology; D018942:Macrolides / Q000627:therapeutic use*; D008297:Male; D010270:Parasite Egg Count / Q000662:veterinary; D016896:Treatment Outcome
chemical_list: D000871:Anthelmintics; D018942:Macrolides; C078973:milbemycin oxime