title: Plasmonic-driven thermal sensing: ultralow detection of cancer markers.
abstract: This communication describes an ultrafast high-sensitivity plasmonic-driven thermal sensing approach for the detection of tumoral markers. Gold nanoprisms derivatized with antibody against carcinoembryonic antigen (anti-CEA) are used to label CEA molecules and imprint thermal signals upon illumination, enabling sensitivities up to the attomolar range in real patient samples.
authors.affiliation: Instituto de Nanociencia de Aragon, Universidad de Zaragoza, 50018 Zaragoza, Spain.
authors.forename: Ester
authors.initials: E
authors.lastname: Polo
authors.forename: Pablo
authors.initials: P
authors.lastname: del Pino
authors.forename: Beatriz
authors.initials: B
authors.lastname: Pelaz
authors.forename: Valeria
authors.initials: V
authors.lastname: Grazu
authors.forename: Jesus M
authors.initials: JM
authors.lastname: de la Fuente
mesh_terms: D000906:Antibodies / Q000737:chemistry*; D014408:Biomarkers, Tumor / Q000097:blood* / Q000276:immunology; D015374:Biosensing Techniques; D002272:Carcinoembryonic Antigen / Q000097:blood* / Q000276:immunology; D006046:Gold / Q000737:chemistry*; D006358:Hot Temperature; D006801:Humans; D049329:Nanostructures / Q000737:chemistry*
chemical_list: D000906:Antibodies; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D006046:Gold