title: Open inguinal hernia repair with the use of polyglycolic acid/trimethylene carbonate mesh: gross and pathologic assessment of the inguinal area at reoperation for recurrence.
abstract: OBJECTIVE
  Our group tried to test the hypothesis of using a totally absorbable material for open inguinal hernia repair. However, the increased incidence of recurrences alleviated our initial enthusiasm regarding the technique. The purpose of the present study was to attain both gross and microscopic data that could at least in part justify the hernia repair failure from a patient included in our initial pilot study and was re-operated for recurrence.
  
  
  METHODS
  A 65-year-old male patient was diagnosed clinically with a recurrence 24 months after open inguinal hernia repair with the use of polyglycolic acid/trimethylene carbonate mesh. The patient was operated for the recurrence upon our group on July 2012. The gross appearance of the inguinal area as well as the degree of chronic inflammation provoked by the used mesh as depicted by the pathologic analysis of specimens obtained intraoperatively were assessed.
  
  
  RESULTS
  An open tension-free repair with the use of a non-absorbable mesh under spinal anesthetic was undertaken. Intraoperatively, after the division of the external oblique aponeurosis, only minor fibrotic reaction was observed a finding that was additionally confirmed pathologically.
  
  
  CONCLUSIONS
  Polyglycolic acid/trimethylene carbonate mesh used for inguinal hernia repair was associated with a minimal inflammatory host reaction in the inguinal area at 3 years verified both grossly and microscopically.
authors.affiliation: Department of General Surgery, University Hospital of Larissa, 41110, Mezourlo, Larissa, Greece, simeonid@hotmail.com.
authors.forename: D
authors.initials: D
authors.lastname: Symeonidis
authors.forename: M
authors.initials: M
authors.lastname: Efthimiou
authors.forename: G
authors.initials: G
authors.lastname: Koukoulis
authors.forename: I
authors.initials: I
authors.lastname: Mamaloudis
authors.forename: M
authors.initials: M
authors.lastname: Ioannou
authors.forename: G
authors.initials: G
authors.lastname: Tzovaras
mesh_terms: D000368:Aged; D004146:Dioxanes / Q000009:adverse effects*; D005549:Foreign-Body Reaction / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006552:Hernia, Inguinal / Q000473:pathology / Q000601:surgery*; D059685:Herniorrhaphy / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D008297:Male; D011100:Polyglycolic Acid / Q000009:adverse effects*; D012008:Recurrence; D012086:Reoperation; D013526:Surgical Mesh / Q000009:adverse effects*
chemical_list: D004146:Dioxanes; D011100:Polyglycolic Acid; C443643:trimethylene carbonate
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