title: Antimicrobial photodynamic therapy for methicillin-resistant Staphylococcus aureus infection.
abstract: Nowadays methicillin-resistant Staphylococcus aureus (MRSA) is one of the most common multidrug resistant bacteria both in hospitals and in the community. In the last two decades, there has been growing concern about the increasing resistance to MRSA of the most potent antibiotic glycopeptides. MRSA infection poses a serious problem for physicians and their patients. Photosensitizer-mediated antimicrobial photodynamic therapy (PDT) appears to be a promising and innovative approach for treating multidrug resistant infection. In spite of encouraging reports of the use of antimicrobial PDT to inactivate MRSA in large in vitro studies, there are only few in vivo studies. Therefore, applying PDT in the clinic for MRSA infection is still a long way off.
authors.affiliation: Department of Burns and Plastic Surgery, No. 3 People's Hospital, and Institute of Traumatic Medicine, School of Medicine, Shanghai Jiao Tong University, 280 Mohe Road, Shanghai 201900, China.
authors.forename: Xiu-Jun
authors.initials: XJ
authors.lastname: Fu
authors.forename: Yong
authors.initials: Y
authors.lastname: Fang
authors.forename: Min
authors.initials: M
authors.lastname: Yao
mesh_terms: D006801:Humans; D008712:Methicillin / Q000008:administration & dosage; D016106:Methicillin Resistance / Q000235:genetics; D055624:Methicillin-Resistant Staphylococcus aureus / Q000235:genetics / Q000472:pathogenicity / Q000528:radiation effects*; D010778:Photochemotherapy; D011023:Pneumonia, Staphylococcal / Q000235:genetics / Q000382:microbiology / Q000628:therapy*
chemical_list: D008712:Methicillin
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