title: Aetiology and clinical features of dysentery in children aged <5 years in rural Bangladesh.
abstract: The study identified the common aetiological agents and prominent clinical features of dysentery cases in children aged <5 years and compared this to non-dysentery diarrhoeal cases from the same population. From January 2010 to December 2011, 2324 children aged <5 years received treatment at Kumudini Hospital, of which 682 (29%) presented with dysentery. Of the dysenteric children, aetiology could not be determined for over half (61%). Shigella spp. accounted for 32% of dysentery cases. Significant associations were found between presence of blood in stool and: child age (24-59 months) [odds ratio (OR) 2.21, 95% confidence interval (CI) 1.49-3.27], no treatment of drinking water at home (OR 2.00, 95% CI 1.09-3.67), vomiting (OR 0.19, 95% CI 0.14-0.25), abdominal pain (OR 4.68, 95% CI 3.24-6.77), straining (OR 16.45, 95% CI 11.92-22.69), wasting (OR 1.66, 95% CI 1.15-2.41), and presence of Shigella in stool (OR 6.25, 95% CI 4.20-9.29) after controlling for confounders. This study makes it clear that appropriate public health strategies are needed to reduce the burden of dysentery in Bangladesh.
authors.affiliation: International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b).
authors.forename: F
authors.initials: F
authors.lastname: Ferdous
authors.forename: S
authors.initials: S
authors.lastname: Ahmed
authors.forename: S K
authors.initials: SK
authors.lastname: DAS
authors.forename: F D
authors.initials: FD
authors.lastname: Farzana
authors.forename: J R
authors.initials: JR
authors.lastname: Latham
authors.forename: M J
authors.initials: MJ
authors.lastname: Chisti
authors.forename: A S G
authors.initials: AS
authors.lastname: Faruque
mesh_terms: D001459:Bangladesh / Q000453:epidemiology; D002675:Child, Preschool; D004403:Dysentery / Q000453:epidemiology* / Q000209:etiology*; D004405:Dysentery, Bacillary / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009752:Nutritional Status; D016017:Odds Ratio; D011446:Prospective Studies; D012307:Risk Factors; D012760:Shigella / Q000302:isolation & purification
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