title: Allopurinol in the treatment of acquired reactive perforating collagenosis.
abstract: Acquired reactive perforating collagenosis is a perforating dermatosis usually associated with different systemic diseases, mainly diabetes mellitus and/or chronic renal insufficiency. Different therapies have been tried but treatment is not standardized yet and remains a challenge. In the last few years, allopurinol has been reported as a good therapeutic option for acquired reactive perforating collagenosis. We describe the case of a 73-year-old man affected by acquired reactive perforating collagenosis associated with diabetes type 1 and chronic renal failure with secondary hyperparathyroidism. The patient was successfully treated with allopurinol 100mg once/day p.o..
authors.affiliation: Department of Dermatology, Division of General Dermatology, Medical University of Graz, Graz, Austria.
authors.forename: Hemma
authors.initials: H
authors.lastname: Tilz
authors.forename: Jürgen Christian
authors.initials: JC
authors.lastname: Becker
authors.forename: Franz
authors.initials: F
authors.lastname: Legat
authors.forename: Antonio Pedro Mendes
authors.initials: AP
authors.lastname: Schettini
authors.forename: Martin
authors.initials: M
authors.lastname: Inzinger
authors.forename: Cesare
authors.initials: C
authors.lastname: Massone
mesh_terms: D000368:Aged; D000493:Allopurinol / Q000627:therapeutic use*; D003095:Collagen Diseases / Q000188:drug therapy* / Q000209:etiology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D016166:Free Radical Scavengers / Q000627:therapeutic use*; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000150:complications; D007676:Kidney Failure, Chronic / Q000150:complications; D008297:Male
chemical_list: D016166:Free Radical Scavengers; D000493:Allopurinol
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