title: HPV vaginal self-sampling among women non-adherent to Papanicolaou screening in Chile.
abstract: OBJECTIVE
  To evaluate acceptance, preference and compliance with referral of vaginal self-sampling for the detection of Human papillomavirus (HPV) among women non-adherent to Papanicolaou (Pap) screening in Santiago, Chile.
  
  
  METHODS
  Using multistage sampling we identified women aged 30-64 years who reported not receiving a Pap test in the previous three years and offered them Pap testing at the health center or vaginal self-sampling for HPV testing at home. Self-collected samples were analyzed with hybrid capture. All HPV+ women were referred for colposcopy, biopsy and treatment when needed.
  
  
  RESULTS
  1 254 eligible women were contacted; 86.5% performed self-sampling and 8.1% refused; 124 women were HPV+ (11.4%: 95%CI 9.6-13.5) of whom 85.5% attended colposcopy; 12 had CIN2+ (1.1%: 95 %CI 0.5-1.7).
  
  
  CONCLUSIONS
  HPV vaginal self-sampling can be easily implemented in Chile and could improve coverage, successfully reaching women who drop out of the screening program.
authors.affiliation: Departamento de Medicina Familiar, Pontificia Universidad Católica de Chile, Santiago, Chile.
authors.forename: Javiera
authors.initials: J
authors.lastname: Léniz
authors.forename: María Isabel
authors.initials: MI
authors.lastname: Barriga
authors.forename: Marcela
authors.initials: M
authors.lastname: Lagos
authors.forename: Carolina
authors.initials: C
authors.lastname: Ibáñez
authors.forename: Klaus
authors.initials: K
authors.lastname: Puschel
authors.forename: Catterina
authors.initials: C
authors.lastname: Ferreccio
mesh_terms: D000328:Adult; D002677:Chile; D059026:Diagnostic Self Evaluation; D005260:Female; D006801:Humans; D008875:Middle Aged; D065006:Papanicolaou Test; D027383:Papillomaviridae / Q000302:isolation & purification*; D010349:Patient Compliance; D017060:Patient Satisfaction; D011795:Surveys and Questionnaires; D014621:Vagina / Q000821:virology*; D014626:Vaginal Smears