title: Case report: Helicobacter suis infection in a pig veterinarian.
abstract: This study describes a non-Helicobacter (H.) pylori Helicobacter (NHPH) infection in a pig veterinarian. The patient suffered from reflux esophagitis and general dyspeptic symptoms and was referred to the hospital for upper gastrointestinal endoscopy. Histologic examination of corpus and antrum biopsies revealed a chronic gastritis. Large spiral-shaped non-H. pylori helicobacters could be visualized and were identified as H. suis by PCR. The patient was treated with a triple therapy, consisting of amoxicillin, clarithromycin, and pantoprazole for 10 days. Successful eradication was confirmed after a follow-up gastrointestinal endoscopy and PCR 10 weeks after treatment. A mild chronic gastritis was, however, still observed at this point in time. This case report associates porcine H. suis strains with gastric disease in humans, thus emphasizing the zoonotic importance of H. suis bacteria from pigs.
authors.affiliation: Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium. myrthe.joosten@ugent.be
authors.forename: Myrthe
authors.initials: M
authors.lastname: Joosten
authors.forename: Bram
authors.initials: B
authors.lastname: Flahou
authors.forename: Tom
authors.initials: T
authors.lastname: Meyns
authors.forename: Annemieke
authors.initials: A
authors.lastname: Smet
authors.forename: Joris
authors.initials: J
authors.lastname: Arts
authors.forename: Lien
authors.initials: L
authors.lastname: De Cooman
authors.forename: Frank
authors.initials: F
authors.lastname: Pasmans
authors.forename: Richard
authors.initials: R
authors.lastname: Ducatelle
authors.forename: Freddy
authors.initials: F
authors.lastname: Haesebrouck
mesh_terms: D053799:2-Pyridinylmethylsulfinylbenzimidazoles / Q000008:administration & dosage; D000328:Adult; D000658:Amoxicillin / Q000008:administration & dosage; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D017291:Clarithromycin / Q000008:administration & dosage; D004359:Drug Therapy, Combination / Q000379:methods; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology; D005756:Gastritis / Q000382:microbiology / Q000473:pathology; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D018247:Helicobacter heilmannii / Q000302:isolation & purification*; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008853:Microscopy; D016273:Occupational Exposure; D000077402:Pantoprazole; D016133:Polymerase Chain Reaction; D013552:Swine; D016896:Treatment Outcome; D018634:Veterinarians
chemical_list: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D000900:Anti-Bacterial Agents; D000658:Amoxicillin; D000077402:Pantoprazole; D017291:Clarithromycin
keywords: Helicobacter suis; dyspepsia; human patient; pigs; reflux esophagitis