title: Creutzfeldt Jakob disease.
abstract: A case of 50 years of age, male with sporadic Creutzfeldt Jakob Disease (sCJD) is reported. Patient had dementia, behavioural abnormalities, unsteady gait and myoclonic jerks. Magnetic resonance imaging (MRI) brain T2 weighted and Fluid Attenuated Inverse Recovery (FLAIR) images showed abnormally increased signal intensity in caudate nucleus and putamen. Scalp electroencephalogram (EEG) revealed periodic synchronous biphasic sharp wave complexes. On the basis of history, clinical findings, typical MRI brain and EEG changes, diagnosis of sporadic CJD was made.
authors.affiliation: Department of Medicine, Military Hospital, Rawalpindi. ehtesham2120@hotmail.com
authors.forename: Ehtesham
authors.initials: E
authors.lastname: Haider
authors.forename: Wasim
authors.initials: W
authors.lastname: Wali
authors.forename: Samiullah
authors.initials: S
authors.lastname: Raja
authors.forename: Muhammad
authors.initials: M
authors.lastname: Tariq
mesh_terms: D001921:Brain / Q000473:pathology*; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D004569:Electroencephalography; D006801:Humans; D008297:Male; D008875:Middle Aged