title: Burden of disease due to dementia in the elderly population of Korea: present and future.
abstract: BACKGROUND
  With the rapid aging of populations around the world, dementia has become one of the most important public health problems in Eastern Asian countries. The purpose of the present study was to provide an estimate of the burden of dementia and forecast its future burden, as generalized to the Korean population, and to provide detailed gender- and age-specific information regarding the burden of dementia in the elderly population of Korea.
  
  
  METHODS
  'Disability-adjusted life years' (DALYs) were used to estimate the burden of dementia. Epidemiologic data from national statistics and nationwide epidemiologic studies in the year 2008 were used to obtain representative outcomes for the Korean population. We estimated the DALYs due to dementia from the years 2010 to 2050 by applying demographic structure projections in terms of 5-year age groups in Korea.
  
  
  RESULTS
  The burden of disease due to dementia in Korea is 528 per 100,000 population (males: 435, females: 622) and 5,117 per 100,000 in those over the age of 65 years (males: 5,228; females: 5,041); this accounts for 4.5% of the total burden of disease in the year 2008. In the year 2050, DALYs due to dementia (814,629) are expected to be 3.0 times higher than those in the year 2010 (274,849).
  
  
  CONCLUSIONS
  Dementia has the highest burden of disease in the elderly Korean population, and this burden will increase sharply with the aging of the population. More comprehensive and multi-dimensional approaches, including clinical, psychological, social, and political means will be needed for the management of the dramatically increasing burden of dementia.
authors.affiliation: Department of Social and Preventive Medicine, Sungkyunkwan University School of Medicine, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi-do 440-746, Republic of Korea.
authors.forename: Jae-Hyun
authors.initials: JH
authors.lastname: Park
authors.forename: Jin-Hee
authors.initials: JH
authors.lastname: Eum
authors.forename: Bolor
authors.initials: B
authors.lastname: Bold
authors.forename: Hae-Kwan
authors.initials: HK
authors.lastname: Cheong
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017281:Cost of Illness; D003704:Dementia / Q000453:epidemiology*; D005260:Female; D005544:Forecasting / Q000379:methods; D006801:Humans; D008297:Male; D015233:Models, Statistical; D019057:Quality-Adjusted Life Years; D056910:Republic of Korea / Q000453:epidemiology
references.citation: Stroke. 1992 Jun;23(6):798-803
references.pmid: 1595095
references.citation: Trop Med Int Health. 1997 Oct;2(10):993-1000
references.pmid: 9357490
references.citation: Neurology. 1998 Oct;51(4):1000-8
references.pmid: 9781520
references.citation: Acta Psychiatr Scand. 1986 Aug;74(2):144-51
references.pmid: 3490741
references.citation: Neurology. 1991 Dec;41(12):1886-92
references.pmid: 1745343
references.citation: Drugs Aging. 1999 Nov;15(5):365-75
references.pmid: 10600044
references.citation: Alzheimers Dement. 2007 Jul;3(3):186-91
references.pmid: 19595937
references.citation: Acta Psychiatr Scand. 1989 Feb;79(2):190-8
references.pmid: 2923012
references.citation: JAMA. 1989 Nov 10;262(18):2551-6
references.pmid: 2810583
references.citation: Int J Geriatr Psychiatry. 2004 Feb;19(2):170-7
references.pmid: 14758582
references.citation: Int J Epidemiol. 1991 Sep;20(3):736-48
references.pmid: 1955260
references.citation: Am J Psychiatry. 1995 Oct;152(10):1485-92
references.pmid: 7573588
references.citation: Geriatr Psychol Neuropsychiatr Vieil. 2012 Sep;10(3):325-31
references.pmid: 23015241
references.citation: Tohoku J Exp Med. 1990 Aug;161 Suppl:29-38
references.pmid: 2082503
references.citation: Am J Public Health. 1998 Oct;88(10):1452-6
references.pmid: 9772843
references.citation: J Am Geriatr Soc. 1998 Apr;46(4):444-52
references.pmid: 9560066
references.citation: Alzheimer Dis Assoc Disord. 2003 Apr-Jun;17(2):63-7
references.pmid: 12794381
references.citation: J Am Geriatr Soc. 1999 Feb;47(2):189-95
references.pmid: 9988290
references.citation: Int J Geriatr Psychiatry. 1999 Aug;14(8):651-61
references.pmid: 10489656
references.citation: Neurology. 1990 Apr;40(4):626-31
references.pmid: 2320236
references.citation: CMAJ. 1994 Mar 15;150(6):899-913
references.pmid: 8131123
references.citation: Int J Geriatr Psychiatry. 2000 Jan;15(1):21-30
references.pmid: 10637401
references.citation: Annu Rev Public Health. 2002;23:213-31
references.pmid: 11910061
references.citation: Neuroepidemiology. 2005;25(3):153-62
references.pmid: 15990446
references.citation: Popul Health Metr. 2003 Apr 14;1(1):4
references.pmid: 12773212
references.citation: J Alzheimers Dis. 2011;23(2):281-91
references.pmid: 21178286
references.citation: BMJ. 1995 Apr 15;310(6985):970-3
references.pmid: 7728032
references.citation: Acta Psychiatr Scand. 1987 Nov;76(5):465-79
references.pmid: 3324647