title: Primary neuroendocrine carcinoma of the breast.
abstract: Primary neuroendocrine carcinoma of the breast (NECB) is an extremely rare variant of breast cancer having aggressive clinicopathological behaviour and poor prognosis. A 62 years old woman presented with a painless lump in the left breast. Microscopic and immunohistochemical evaluation of the core-tissue biopsy and of the mastectomy specimen revealed moderately-differentiated neuroendocrine carcinoma of the breast. She was labeled as a case of primary neuroendocrine carcinoma of the breast after an infallible exclusion of any concomitant lesion elsewhere in the body. Modified radical mastectomy with level II axillary clearance, chemoradiotherapy and Famoxifen have led to an uneventful 5-year survival till the last follow-up.
authors.affiliation: Department of General Surgery, PAEC General Hospital, Islamabad. surgeonarehman@yahoo.com
authors.forename: Abdul
authors.initials: A
authors.lastname: Rehman
mesh_terms: D001365:Axilla / Q000473:pathology / Q000601:surgery; D001706:Biopsy; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D018278:Carcinoma, Neuroendocrine / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D018288:Carcinoma, Small Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D059248:Chemoradiotherapy; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008327:Mammography; D015411:Mastectomy, Modified Radical; D008875:Middle Aged; D016896:Treatment Outcome