title: Effect of graft patency on the prediction of myocardial viability by dobutamine stress and myocardial contrast echocardiography before coronary artery bypass surgery.
abstract: BACKGROUND
  Myocardial functional recovery after revascularization is considered the "gold standard" for myocardial viability (MV) assessment. However, the patency of the revascularized coronary artery affects myocardial functional recovery in patients subjected to coronary artery bypass grafting (CABG). The influence of graft patency on viability results has not been widely studied.
  
  
  OBJECTIVE
  We evaluated the effect of graft patency on the prediction of MV after CABG by myocardial contrast echocardiography (MCE) and low-dose dobutamine stress echocardiography (LD-DSE).
  
  
  METHODS
  Fifty-three subjects with chronic ischemic heart disease scheduled for CABG were divided randomly into groups A (n = 26) and B (n = 27). They underwent MCE and LD-DSE preoperatively. Patients were followed up 12 months after CABG. Group B patients underwent multislice computed tomography angiography to assess CABG patency, and patients with obstructed grafts were excluded. Group A patients were not subjected to multislice CT angiography. The accuracy of MCE and LD-DSE for assessing MV between the two groups was compared.
  
  
  RESULTS
  The accuracy and positive predictive values of MCE and LD-DSE for predicting MV were higher in group B than in group A (p < 0.05).
  
  
  CONCLUSIONS
  Preoperative LD-DSE and MCE ability to predict MV depends on the patency of CABG.
authors.affiliation: Department of Cardiovascular Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, 150001, The People's Republic of China.
authors.forename: Chang
authors.initials: C
authors.lastname: Liu
authors.forename: Chun-hong
authors.initials: CH
authors.lastname: Xiu
authors.forename: Xi-gang
authors.initials: XG
authors.lastname: Xiao
authors.forename: Li-xin
authors.initials: LX
authors.lastname: Ni
authors.forename: Zong-hong
authors.initials: ZH
authors.lastname: Liu
authors.forename: Bai-chun
authors.initials: BC
authors.lastname: Wang
authors.forename: Jing-xia
authors.initials: JX
authors.lastname: Shen
authors.forename: Kai
authors.initials: K
authors.lastname: Zhu
authors.forename: Guo-wei
authors.initials: GW
authors.lastname: Zhang
authors.forename: Lei
authors.initials: L
authors.lastname: Xu
authors.forename: Hong-yu
authors.initials: HY
authors.lastname: Liu
mesh_terms: D058665:Adrenergic beta-1 Receptor Agonists; D000368:Aged; D003287:Contrast Media; D001026:Coronary Artery Bypass; D004280:Dobutamine; D025401:Echocardiography, Stress; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging / Q000601:surgery*; D015588:Observer Variation; D010743:Phospholipids; D011237:Predictive Value of Tests; D011300:Preoperative Care; D012680:Sensitivity and Specificity; D013459:Sulfur Hexafluoride; D016896:Treatment Outcome
chemical_list: D058665:Adrenergic beta-1 Receptor Agonists; D003287:Contrast Media; D010743:Phospholipids; C420843:contrast agent BR1; D004280:Dobutamine; D013459:Sulfur Hexafluoride
keywords: graft patency; low-dose dobutamine stress echocardiography; myocardial contrast echocardiography; myocardial viability