title: Clinically severe Epstein-Barr virus encephalitis with mild cerebrospinal fluid abnormalities in an immunocompetent adolescent: a case report.
abstract: A 15-year-old boy developed Epstein-Barr virus (EBV) encephalitis, a rare complication of infectious mononucleosis. The severe clinical picture and the marked neuroimaging changes were in contrast with mild cerebrospinal fluid abnormalities: leukocyte count was normal and protein level was only slightly elevated. EBV DNA was detected in cerebrospinal fluid by polymerase chain reaction.
authors.affiliation: University Lille 2, Faculty of Medicine, CHRU Lille, Laboratory of Virology EA3610, Loos-lez-Lille 59120, France. ilka.engelmann@chru-lille.fr
authors.forename: Ilka
authors.initials: I
authors.lastname: Engelmann
authors.forename: Hala
authors.initials: H
authors.lastname: Nasser
authors.forename: Soufien
authors.initials: S
authors.lastname: Belmiloudi
authors.forename: Rémi
authors.initials: R
authors.lastname: Le Guern
authors.forename: Anny
authors.initials: A
authors.lastname: Dewilde
authors.forename: Louis
authors.initials: L
authors.lastname: Vallée
authors.forename: Didier
authors.initials: D
authors.lastname: Hober
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology / Q000821:virology; D004279:DNA, Viral / Q000134:cerebrospinal fluid / Q000302:isolation & purification; D004660:Encephalitis / Q000134:cerebrospinal fluid* / Q000150:complications; D004854:Herpesvirus 4, Human / Q000254:growth & development / Q000302:isolation & purification*; D006801:Humans; D007244:Infectious Mononucleosis / Q000134:cerebrospinal fluid* / Q000150:complications / Q000821:virology*; D008279:Magnetic Resonance Imaging; D008297:Male; D016133:Polymerase Chain Reaction
chemical_list: D004279:DNA, Viral