title: Inner-ear sound pressures near the base of the cochlea in chinchilla: further investigation.
abstract: The middle-ear pressure gain GMEP, the ratio of sound pressure in the cochlear vestibule PV to sound pressure at the tympanic membrane PTM, is a descriptor of middle-ear sound transfer and the cochlear input for a given stimulus in the ear canal. GMEP and the cochlear partition differential pressure near the cochlear base ΔPCP, which determines the stimulus for cochlear partition motion and has been linked to hearing ability, were computed from simultaneous measurements of PV, PTM, and the sound pressure in scala tympani near the round window PST in chinchilla. GMEP magnitude was approximately 30 dB between 0.1 and 10 kHz and decreased sharply above 20 kHz, which is not consistent with an ideal transformer or a lossless transmission line. The GMEP phase was consistent with a roughly 50-μs delay between PV and PTM. GMEP was little affected by the inner-ear modifications necessary to measure PST. GMEP is a good predictor of ΔPCP at low and moderate frequencies where PV >> PST but overestimates ΔPCP above a few kilohertz where PV ≈ PST. The ratio of PST to PV provides insight into the distribution of sound pressure within the cochlear scalae.
authors.affiliation: Eaton-Peabody Laboratory, Massachusetts Eye & Ear Infirmary, 243 Charles Street, Boston, Massachusetts 02114, USA. mike_ravicz@meei.harvard.edu
authors.forename: Michael E
authors.initials: ME
authors.lastname: Ravicz
authors.forename: John J
authors.initials: JJ
authors.lastname: Rosowski
mesh_terms: D000161:Acoustic Stimulation; D000162:Acoustics / Q000295:instrumentation; D000818:Animals; D002682:Chinchilla / Q000502:physiology*; D007758:Ear, Inner / Q000502:physiology*; D040542:Mechanotransduction, Cellular; D009068:Movement; D011312:Pressure; D012533:Scala Tympani / Q000502:physiology; D054738:Scala Vestibuli / Q000502:physiology; D013016:Sound; D013018:Sound Spectrography; D013997:Time Factors; D014160:Transducers, Pressure; D014432:Tympanic Membrane / Q000502:physiology
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