title: The first report of infection with Klebsiella pneumoniae carrying the bla(kpc) gene in State of Mato Grosso do Sul, Brazil.
abstract: The increased frequency and dissemination of enterobacteria resistant to various antimicrobials is currently worldwide concern. In January 2010, a 94-year-old patient with chronic lymphocytic leukemia was admitted to the University Hospital. This patient died 21 days after hospitalization due to the clinical worsening. Klebsiella pneumoniae producing of extended-spectrum β-lactamases (ESBLs) was isolated of urine culture. This bacterium demonstrated resistance to ceftazidime, ciprofloxacin, levofloxacin, ertapenem and imipenem. Susceptibility to cefoxitin, cefepime, meropenem, colistin and tigecycline. This study reports the first case of infection by Klebsiella pneumoniae carrying the bla(kpc) gene in the State of Mato Grosso do Sul, Brazil.
authors.affiliation: Laboratório de Pesquisas Microbiológicas, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brasil. marirchang@yahoo.com.br
authors.forename: Marilene Rodrigues
authors.initials: MR
authors.lastname: Chang
authors.forename: Camila Arguelo
authors.initials: CA
authors.lastname: Biberg
authors.forename: Fernando Aguilar
authors.initials: FA
authors.lastname: Lopes
authors.forename: Andyane Freitas
authors.initials: AF
authors.lastname: Tetila
authors.forename: Antonio Carlos Campos
authors.initials: AC
authors.lastname: Pignatari
mesh_terms: D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001938:Brazil; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000201:enzymology*; D008826:Microbial Sensitivity Tests; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases