title: Rapid anti-transglutaminase assay and patient interview for monitoring dietary compliance in celiac disease.
abstract: OBJECTIVE
  The anti-transglutaminase antibodies (anti-tTG) play an important role in monitoring the celiacs' gluten-free diet (GFD).
  
  
  METHODS
  The authors propose to use the rapid IgA anti-tTG assay based on a whole blood drop to evaluate the compliance to GFD at the clinical ambulatory setting. The rapid test results were compared with those of the conventional ELISA assay and with dietary compliance reported by patients' interview.
  
  
  CONCLUSIONS
  The authors showed that anti-tTG rapid test is reliable and easy to perform in the ambulatory setting to evaluate dietary compliance. Moreover, they proved that celiacs' interview is more sensitive than serology in identifying patients who transgress.
authors.affiliation: Department of Pediatrics, Institute for Maternal and Child Health - IRCCS "Burlo Garofolo", Trieste, Italy. chiara.zanchi@libero.it
authors.forename: Chiara
authors.initials: C
authors.lastname: Zanchi
authors.forename: Alessandro
authors.initials: A
authors.lastname: Ventura
authors.forename: Stefano
authors.initials: S
authors.lastname: Martelossi
authors.forename: Grazia
authors.initials: G
authors.lastname: Di Leo
authors.forename: Nicola
authors.initials: N
authors.lastname: Di Toro
authors.forename: Tarcisio
authors.initials: T
authors.lastname: Not
mesh_terms: D000293:Adolescent; D000328:Adult; D002446:Celiac Disease / Q000178:diet therapy* / Q000276:immunology*; D002648:Child; D055050:Diet, Gluten-Free; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D019204:GTP-Binding Proteins; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D000091345:Protein Glutamine gamma Glutamyltransferase 2; D012680:Sensitivity and Specificity; D013997:Time Factors; D011503:Transglutaminases / Q000276:immunology*; D055815:Young Adult
chemical_list: D007070:Immunoglobulin A; D000091345:Protein Glutamine gamma Glutamyltransferase 2; D011503:Transglutaminases; D019204:GTP-Binding Proteins