title: Goodbye ISAAC, farewell Joseph.
authors.forename: Luis
authors.initials: L
authors.lastname: Garcia-Marcos
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D001249:Asthma / Q000453:epidemiology* / Q000235:genetics; D002648:Child; D017326:Clinical Trials, Phase III as Topic; D003231:Conjunctivitis / Q000453:epidemiology* / Q000235:genetics; D003625:Data Collection; D004485:Eczema / Q000453:epidemiology* / Q000235:genetics; D059647:Gene-Environment Interaction; D006801:Humans; D015995:Prevalence; D012220:Rhinitis / Q000453:epidemiology* / Q000235:genetics