title: Reply to commentary.
authors.affiliation: Inflexxion, Inc, 320 Needham St., Newton, MA 02464, USA. sfbutler@inflexxion.com
authors.forename: Stephen F
authors.initials: SF
authors.lastname: Butler
mesh_terms: D000701:Analgesics, Opioid / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D009293:Opioid-Related Disorders / Q000453:epidemiology* / Q000517:prevention & control*; D010098:Oxycodone / Q000008:administration & dosage*
chemical_list: D000701:Analgesics, Opioid; D010098:Oxycodone