title: [Genotype of hantavirus in Zhejiang province].
abstract: OBJECTIVE
  To identify the genotype and clades of hantavirus (HV) in Zhejiang province.
  
  
  METHODS
  The partial S and M segment of the HV in Zhejiang province were amplified with RT-PCR using genotype-specific primers, and then were sequenced and compared with other known hantaviruses.
  
  
  RESULTS
  The genotype of 11 strains were HTNV and other 7 strains were SEOV by homology and phylogenesis analysis, yet the clade distribution was significantly different among foci of Zhejiang with 5 clades of HTNV and 3 clades of SEOV. There also existed special clade of HTNV named ZNB-1, ZNB-2, A3 and of SEOV named Gou3, ZJ5. The homology of M segments of ZNB-1 and ZNB-2 with other HTNV clades were 69.7%-74.0% except Nc167, A3 with other HTNV clades were 73.6%-76.3% except B78.
  
  
  CONCLUSIONS
  Zhejiang province is co-circulating with HTN and SEO. Say the least of the clades are 5 of HTNV and 3 of SEOV and there also existed special clade of HTNV and SEOV.
authors.affiliation: Zhejiang Center for Disease Prevention and Control, Hangzhou 310051, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Xu
authors.forename: Ping-Ping
authors.initials: PP
authors.lastname: Yao
authors.forename: Han-Ping
authors.initials: HP
authors.lastname: Zhu
authors.forename: Jie
authors.initials: J
authors.lastname: Whang
authors.forename: Lei
authors.initials: L
authors.lastname: Qian
authors.forename: Qun
authors.initials: Q
authors.lastname: Hu
authors.forename: Shu-Mei
authors.initials: SM
authors.lastname: Tong
authors.forename: Xiao-Seng
authors.initials: XS
authors.lastname: Deng
authors.forename: Rong-Hui
authors.initials: RH
authors.lastname: Xie
authors.forename: Zhang-Nv
authors.initials: ZN
authors.lastname: Yang
authors.forename: Yun
authors.initials: Y
authors.lastname: Zhang
authors.forename: Zhi-Yong
authors.initials: ZY
authors.lastname: Zhu
mesh_terms: D002681:China; D005838:Genotype; D006476:Orthohantavirus / Q000145:classification* / Q000235:genetics; D010802:Phylogeny; D060888:Real-Time Polymerase Chain Reaction