title: Hemoptysis and respiratory failure following sildenafil use for pulmonary hypertension.
abstract: Sildenafil, usually a well-tolerated drug traditionally used for erectile dysfunction (ED), was recently approved for pulmonary arterial hypertension. In the literature, there are few cases of hemoptysis following sildenafil use for ED; however, to our knowledge, we are reporting the first case of hemoptysis following sildenafil use for pulmonary hypertension. We are documenting a case of a 90-year-old male patient who was admitted to the intensive care unit with hemoptysis and respiratory failure two weeks after he was started on sildenafil.
authors.affiliation: East Tennessee State University, USA. souheilabdelnour@yahoo.com
authors.forename: Souheil M Abdel
authors.initials: SM
authors.lastname: Nour
authors.forename: Holly Abdel
authors.initials: HA
authors.lastname: Nour
authors.forename: Jay B
authors.initials: JB
authors.lastname: Mehta
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Roy
authors.forename: Ryland P
authors.initials: RP
authors.lastname: Byrd
mesh_terms: D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use; D001241:Aspirin / Q000009:adverse effects / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006469:Hemoptysis / Q000139:chemically induced*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy*; D007362:Intensive Care Units; D008297:Male; D010343:Patient Admission; D010879:Piperazines / Q000009:adverse effects* / Q000627:therapeutic use; D011687:Purines / Q000009:adverse effects / Q000627:therapeutic use; D012131:Respiratory Insufficiency / Q000139:chemically induced*; D000068677:Sildenafil Citrate; D013450:Sulfones / Q000009:adverse effects* / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D014665:Vasodilator Agents; D000068677:Sildenafil Citrate; D001241:Aspirin