title: Tembusu virus in human, China.
abstract: Tembusu virus (TMUV) infection in ducks, geese and house sparrows was reported in China. To confirm the emergence of TMUV in humans, we investigated TMUV as a possible infection in duck industry workers in Shandong, China. Of 132 serum samples tested, 95 (71.9%) had TMUV antibodies. In oral swabs detection, 63 (47.7%) samples were positive for TMUV RNA. Nucleotide sequences of 277 bp coding the partial NS3 protein showed more than 99.5% identity with other duck TMUV strains, which can cause severe egg drop in ducks. These findings contribute to the realization that TMUV may be overlooked as a zoonotic transmission in China.
authors.affiliation: Institute of Poultry Disease, Shan Dong Agricultural University, Shandong, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Tang
authors.forename: X
authors.initials: X
authors.lastname: Gao
authors.forename: Y
authors.initials: Y
authors.lastname: Diao
authors.forename: Q
authors.initials: Q
authors.lastname: Feng
authors.forename: H
authors.initials: H
authors.lastname: Chen
authors.forename: X
authors.initials: X
authors.lastname: Liu
authors.forename: P
authors.initials: P
authors.lastname: Ge
authors.forename: C
authors.initials: C
authors.lastname: Yu
mesh_terms: D000818:Animals; D057134:Antibodies, Neutralizing / Q000097:blood; D000914:Antibodies, Viral / Q000097:blood*; D002681:China; D004372:Ducks / Q000821:virology; D004797:Enzyme-Linked Immunosorbent Assay; D019143:Evolution, Molecular; D005416:Flavivirus / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*; D018177:Flavivirus Infections / Q000175:diagnosis*; D006801:Humans; D009061:Mouth Mucosa / Q000821:virology*; D009784:Occupational Diseases / Q000175:diagnosis; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D011201:Poultry Diseases / Q000175:diagnosis / Q000821:virology; D020365:RNA Helicases / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics; D012367:RNA, Viral / Q000097:blood / Q000235:genetics; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012697:Serine Endopeptidases / Q000235:genetics; D019562:Viral Load; D017361:Viral Nonstructural Proteins / Q000235:genetics*; D043583:Nucleoside-Triphosphatase; D053487:DEAD-box RNA Helicases; D000085242:Viral Proteases
chemical_list: D057134:Antibodies, Neutralizing; D000914:Antibodies, Viral; D020365:RNA Helicases; D012333:RNA, Messenger; D012367:RNA, Viral; D012697:Serine Endopeptidases; D017361:Viral Nonstructural Proteins; C060028:NS3 protein, flavivirus; D043583:Nucleoside-Triphosphatase; D053487:DEAD-box RNA Helicases; D000085242:Viral Proteases