title: Oncogenic osteomalacia diagnosed by blood pool scintigraphy.
abstract: Oncogenic osteomalacia is a rare metabolic bone disease characterized by phosphaturia and hypophosphatemia. Certain tumors secrete a phosphaturic factor, which results in this metabolic abnormality; this factor called as phosphatonin, is in fact a fibroblast growth factor 23 (FGF-23) involved closely in phosphate homeostasis and skeletogenesis. Complete excision of these tumors facilitates reversal of the problem. We have reported here the case of a patient who was crippled with this disease and on thorough investigation revealed an oncogenic osteomalacia with tumor focus in the right tibia. The tumor was identified as a mesenchymal tumor, i.e., hemangiopericytoma. Tumor excision alleviated patient symptoms with rapid symptomatic and biochemical improvement.
authors.affiliation: Department of Nuclear Medicine and PET/CT, Amrita Institute of Medical Sciences and Research Center, Cochin, Kerala, India.
authors.forename: Shanmuga Sundaram
authors.initials: SS
authors.lastname: Palaniswamy
authors.forename: Padma
authors.initials: P
authors.lastname: Subramanyam
authors.forename: Harish
authors.initials: H
authors.lastname: Kumar
keywords: Hemangiopericytoma; Tc 99m MDP bone scan; oncogenic osteomalacia; reb blood cell blood pool scan
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