title: MicroRNA function in NK-cell biology.
abstract: The important role of microRNAs in directing immune responses has become increasingly clear. Here, we highlight discoveries uncovering the role of specific microRNAs in regulating the development and function of natural killer (NK) cells. Furthermore, we discuss the impact of NK cells on the entire immune system during global and specific microRNA ablation in the settings of inflammation, infection, and immune dysregulation.
authors.affiliation: Immunology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
authors.forename: Aimee M
authors.initials: AM
authors.lastname: Beaulieu
authors.forename: Natalie A
authors.initials: NA
authors.lastname: Bezman
authors.forename: Jang Eun
authors.initials: JE
authors.lastname: Lee
authors.forename: Mehrdad
authors.initials: M
authors.lastname: Matloubian
authors.forename: Joseph C
authors.initials: JC
authors.lastname: Sun
authors.forename: Lewis L
authors.initials: LL
authors.lastname: Lanier
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000235:genetics; D003602:Cytotoxicity, Immunologic / Q000235:genetics; D006706:Homeostasis; D006801:Humans; D007154:Immune System Diseases / Q000235:genetics / Q000276:immunology*; D056747:Immunomodulation; D007694:Killer Cells, Natural / Q000276:immunology*; D035683:MicroRNAs / Q000235:genetics / Q000276:immunology*; D009369:Neoplasms / Q000235:genetics / Q000276:immunology*; D034622:RNA Interference / Q000276:immunology
chemical_list: D035683:MicroRNAs
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