title: Acute pancreatitis caused by bortezomib.
abstract: Drug-induced pancreatitis has been reported rarely. Bortezomib is a selective and reversible proteasome inhibitor used for the treatment of patients with multiple myeloma (MM). Recently, one case report about acute pancreatitis (AP) caused by bortezomib was published in the international literature. Herein we report a case of AP in a 67-year-old male on bortezomib therapy. On the fourth day after the first administration of bortezomib, the patient admitted to the hospital with symptoms of AP. The common etiological factors for AP were all excluded. Than the patient was diagnosed as bortezomib-induced pancreatitis.
authors.affiliation: Department of Gastroenterology, Ankara Ataturk Research and Education Hospital, Bilkent Street, 06800 Ankara, Turkey. tfksolak@yahoo.com.tr
authors.forename: Tevfik
authors.initials: T
authors.lastname: Solakoglu
authors.forename: Pinar
authors.initials: P
authors.lastname: Akyol
authors.forename: Tekin
authors.initials: T
authors.lastname: Guney
authors.forename: Imdat
authors.initials: I
authors.lastname: Dilek
authors.forename: Roni
authors.initials: R
authors.lastname: Atalay
authors.forename: Huseyin
authors.initials: H
authors.lastname: Koseoglu
authors.forename: Ebru
authors.initials: E
authors.lastname: Akin
authors.forename: Aylin
authors.initials: A
authors.lastname: Demirezer Bolat
authors.forename: Naciye Semnur
authors.initials: NS
authors.lastname: Buyukasik
authors.forename: Osman
authors.initials: O
authors.lastname: Ersoy
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001897:Boronic Acids / Q000009:adverse effects* / Q000627:therapeutic use; D000069286:Bortezomib; D003907:Dexamethasone / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009101:Multiple Myeloma / Q000188:drug therapy; D010195:Pancreatitis / Q000139:chemically induced* / Q000473:pathology; D011719:Pyrazines / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D001897:Boronic Acids; D011719:Pyrazines; D000069286:Bortezomib; D003907:Dexamethasone