title: Novel approaches for the synthesis of a library of fluorescent chromenopyrimidine derivatives.
abstract: A library of some new fluorescent chromenopyrimidine derivatives has been synthesized by new approaches. Water-promoted and one-pot reaction can produce new dialkylylamino)-5H-chromeno[2,3-d]pyrimidin-2-yl) phenols. These compounds can also be produced using domino reaction. Two parallel methods are compared. Novel N-alkyl-N-phenyl-5H-chromeno[2,3-d]-pyrimidin-4-amines and 4-alkoxy-5H-chromeno[2, 3-d]pyrimidines are synthesized by Lewis-acid catalyzed reactions. The fluorescence emission intensity of the four compounds from each of libraries after excitation in 290 nm is measured. Compound 2-(4,5-bis(N-methyl-N-phenylamino)-5H-chromeno[2,3-d]pyrimidin-2-yl)phenol was isolated as a byproduct. The details of an interesting exchangeable intramolecular H- bonding of two of the new compounds are reported by X-ray analysis data.
authors.affiliation: School of Chemistry,University College of Science, University of Tehran , Tehran, Iran.
authors.forename: Afsaneh
authors.initials: A
authors.lastname: Zonouzi
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Hosseinzadeh
authors.forename: Nastaran
authors.initials: N
authors.lastname: Karimi
authors.forename: Roghieh
authors.initials: R
authors.lastname: Mirzazadeh
authors.forename: Seik Weng
authors.initials: SW
authors.lastname: Ng
mesh_terms: D001578:Benzopyrans / Q000737:chemistry*; D018360:Crystallography, X-Ray; D005456:Fluorescent Dyes / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008958:Models, Molecular; D011743:Pyrimidines / Q000138:chemical synthesis*; D013055:Spectrophotometry, Infrared
chemical_list: D001578:Benzopyrans; D005456:Fluorescent Dyes; D011743:Pyrimidines