title: Role of intraoperative squash smear cytology as a diagnostic modality in lipoma of quadrigeminal cistern.
abstract: Quadrigeminal lipoma is a rare tumor that has been categorized as developmental malformation rather than a hamartoma or true neoplasm, due to its origin from abnormal persistence and mal-differentiation of meninx primitiva during the development of the subarachnoid cisterns. Reported admixture of adipose tissue with heterotopic elements also supports a developmental origin. Quadrigeminal lipomas are frequently asymptomatic and detected incidentally. Though a favorable clinical course is usually expected, recurrences may occur due to partial removal of lesions in close relation to vital structure. We describe the role of intraoperative squash smear cytology as a diagnostic aid in quadrigeminal cistern lipoma and an alternative to frozen sections that are technically difficult to obtain due to presence of lobules of fibro-adipose tissue. With radiological correlation, squash cytology can be an economical method for intraoperative diagnosis, pending subsequent histopathological confirmation.
authors.affiliation: Department of Pathology, G B Pant Hospital, Jawaharlal Nehru Marg, New Delhi, India.
authors.forename: Kaushik
authors.initials: K
authors.lastname: Majumdar
authors.forename: Ravindra Kumar
authors.initials: RK
authors.lastname: Saran
authors.forename: Ila
authors.initials: I
authors.lastname: Tyagi
authors.forename: Ravi
authors.initials: R
authors.lastname: Shankar
authors.forename: Daljit
authors.initials: D
authors.lastname: Singh
keywords: Cytology; lipoma; quadrigeminal; squash
references.citation: Neurol Med Chir (Tokyo). 1995 Mar;35(3):175-8
references.pmid: 7770114
references.citation: J Nippon Med Sch. 2000 Oct;67(5):388-91
references.pmid: 11031374
references.citation: J Korean Med Sci. 1996 Dec;11(6):537-9
references.pmid: 9008105
references.citation: J Neuroimaging. 1999 Jul;9(3):134-40
references.pmid: 10436754
references.citation: AJNR Am J Neuroradiol. 1990 Jul-Aug;11(4):665-74
references.pmid: 21510446
references.citation: Tohoku J Exp Med. 2002 Nov;198(3):203-6
references.pmid: 12597248
references.citation: Rev Neurol. 2003 Sep 16-30;37(6):515-21
references.pmid: 14533067
references.citation: Pediatr Radiol. 1998 Sep;28(9):729-31
references.pmid: 9732507
references.citation: J Clin Neurosci. 2005 Jun;12(5):596-9
references.pmid: 15936197