title: Chemical constituents derived from Drimys brasiliensis Miers (Winteraceae).
abstract: Phytochemical investigation on Drimys brasiliensis afforded the isolation and characterisation of four drimane sesquiterpenes: polygodial (1), warburganal (2), 1-β-(p-coumaroyloxy)polygodial (3) and 1-β-(p-methoxycinnamoyl)polygodial (4), as well as four flavonoids: quercitrin (5), astilbin (6), isoastilbin (7) and neoastilbin (8). The structures were elucidated on the basis of their spectral data and compared with those reported in the literature. Compounds 2, 5-8 have been reported to occur for the first time in D. brasiliensis, while compounds 5, 7 and 8 have been reported to occur for the first time in the genus Drimys. The chemotaxonomic significance of these compounds, mainly flavonoids 5-8 in D. brasiliensis, was summarised.
authors.affiliation: a Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo , Diadema, SP , Brazil.
authors.forename: Murillo C
authors.initials: MC
authors.lastname: Mecchi
authors.forename: João Henrique G
authors.initials: JH
authors.lastname: Lago
mesh_terms: D032424:Drimys / Q000737:chemistry*; D000431:Ethanol; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification*; D006586:Hexanes; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry*; D010936:Plant Extracts / Q000032:analysis*; D018515:Plant Leaves / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D005419:Flavonoids; D006586:Hexanes; D010936:Plant Extracts; D012717:Sesquiterpenes; D000431:Ethanol