title: Spinal cord stimulation in cluster headache.
abstract: Neurostimulation techniques for the treatment of primary headache syndromes, particularly for chronic cluster headache (CCH), have received much interest in the recent years. Occipital nerve stimulation (ONS) has yielded favourable clinical results, and is becoming a routine treatment for refractory chronic cluster headache in specialized centres. Meanwhile, other promising techniques, such as spinal cord stimulation (SCS) or sphenopalatine ganglion stimulation, are emerging. This article reviews the current state of clinical research for neurostimulation techniques for chronic cluster headache, and particularly the pros and cons of SCS and ONS.
authors.affiliation: Interdisciplinary Pain Centre, University Hospital Freiburg, Breisacherstr. 64,79106 Freiburg, Germany. tilman.wolter@uniklinik-freiburg.de
authors.forename: Tilman
authors.initials: T
authors.lastname: Wolter
authors.forename: Holger
authors.initials: H
authors.lastname: Kaube
mesh_terms: D000818:Animals; D003027:Cluster Headache / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy*; D046690:Deep Brain Stimulation / Q000379:methods; D006801:Humans; D011859:Radiography; D062187:Spinal Cord Stimulation / Q000379:methods*; D016896:Treatment Outcome
references.citation: Neurosurgery. 2003 May;52(5):1095-9; discussion 1099-101
references.pmid: 12699552
references.citation: Pain. 2004 Mar;108(1-2):137-47
references.pmid: 15109517
references.citation: Brain. 2005 Apr;128(Pt 4):940-7
references.pmid: 15689358
references.citation: Headache. 1988 Jun;28(5):328-31
references.pmid: 3261287
references.citation: Anesth Analg. 1967 Jul-Aug;46(4):489-91
references.pmid: 4952225
references.citation: Br J Anaesth. 2004 Mar;92(3):348-53
references.pmid: 14742334
references.citation: Anesthesiology. 2010 Dec;113(6):1265-7
references.pmid: 21042195
references.citation: Pain Physician. 2007 Mar;10(2):305-11
references.pmid: 17387353
references.citation: Br J Neurosurg. 1993;7(5):483-90
references.pmid: 7505590
references.citation: Circulation. 1998 Mar 31;97(12):1157-63
references.pmid: 9537342
references.citation: Curr Pain Headache Rep. 2010 Apr;14(2):151-9
references.pmid: 20425205
references.citation: Brain. 2002 Jul;125(Pt 7):1496-509
references.pmid: 12077000
references.citation: Lancet. 2007 Mar 31;369(9567):1099-106
references.pmid: 17398309
references.citation: J Neurol Neurosurg Psychiatry. 2005 Feb;76(2):218-21
references.pmid: 15654036
references.citation: Acta Neurochir Suppl. 1995;64:109-15
references.pmid: 8748596
references.citation: Cephalalgia. 2011 Jul;31(10):1101-5
references.pmid: 21727143
references.citation: Acta Neurochir Suppl. 1995;64:119-24
references.pmid: 8748598
references.citation: Headache. 2011 Mar;51(3):418-425
references.pmid: 21269299
references.citation: Neurosci Lett. 1998 May 15;247(2-3):183-6
references.pmid: 9655623
references.citation: Headache. 1988 Nov;28(10):669-70
references.pmid: 3230000
references.citation: J Neurosurg Spine. 2006 Sep;5(3):183-90
references.pmid: 16961078
references.citation: Cephalalgia. 2006 Sep;26(9):1168-70
references.pmid: 16919073
references.citation: Anesth Analg. 2002 Mar;94(3):694-700; table of contents
references.pmid: 11867400
references.citation: Schmerz. 2010 Sep;24(5):441-8
references.pmid: 20872125
references.citation: Neuromodulation. 1999 Jul;2(3):202-10
references.pmid: 22151209
references.citation: Cephalalgia. 2008 Oct;28(10):1091-4
references.pmid: 18727646
references.citation: J Neurosurg. 1989 Apr;70(4):519-24
references.pmid: 2538588
references.citation: Expert Rev Neurother. 2011 Apr;11(4):473-5
references.pmid: 21469918
references.citation: Neurosurgery. 2007 Mar;60(3):E580-1; discussioin E581
references.pmid: 17327771
references.citation: Neurology. 2004 Feb 10;62(3):516-7
references.pmid: 14872051
references.citation: Cent Eur Neurosurg. 2011 May;72(2):84-9
references.pmid: 21448856
references.citation: Pain. 2007 Nov;132(1-2):179-88
references.pmid: 17845835
references.citation: Cephalalgia. 2011 Aug;31(11):1170-80
references.pmid: 21700642
references.citation: Spine (Phila Pa 1976). 2007 Sep 1;32(19):E565-8
references.pmid: 17762800
references.citation: Headache. 2010 Jul;50(7):1164-74
references.pmid: 20438584
references.citation: Neurosurgery. 1996 Aug;39(2):367-74; discussion 374-5
references.pmid: 8832675
references.citation: Arch Neurol. 1986 May;43(5):479-82
references.pmid: 3964115
references.citation: Neurosurgery. 2006 Dec;59(6):1258-62; discussion 1262-3
references.pmid: 17277688
references.citation: Neuromodulation. 1999 Jul;2(3):217-21
references.pmid: 22151211
references.citation: Spine (Phila Pa 1976). 2005 Jan 1;30(1):152-60
references.pmid: 15626996
references.citation: Neuroscience. 2002;112(3):541-53
references.pmid: 12074897
references.citation: Neurosurgery. 2006 Dec;59(6):1252-7; discussion 1257
references.pmid: 17277687
references.citation: Headache. 2011 Sep;51(8):1191-201
references.pmid: 21848953
references.citation: J Neurosurg. 2004 Mar;100(3 Suppl Spine):254-67
references.pmid: 15029914
references.citation: Lancet. 1998 Jul 25;352(9124):275-8
references.pmid: 9690407
references.citation: Pain. 1993 Jan;52(1):55-61
references.pmid: 8446436
references.citation: Rev Neurol. 2010 Jul 1;51(1):19-26
references.pmid: 20568064
references.citation: Neurosurgery. 1994 Mar;34(3):484-8; discussion 488-9
references.pmid: 8190224
references.citation: Eur J Pain. 2005 Aug;9(4):363-73
references.pmid: 15979016
references.citation: Cephalalgia. 2007 Feb;27(2):153-7
references.pmid: 17257236
references.citation: Headache. 1990 Jun;30(7):401-6
references.pmid: 2401621
references.citation: N Engl J Med. 2006 Jun 1;354(22):2394-6
references.pmid: 16738284
references.citation: Cephalalgia. 2005 Jun;25(6):460-5
references.pmid: 15910572
references.citation: J Neurosurg. 1997 Dec;87(6):876-80
references.pmid: 9384398
references.citation: Pain. 2008 Sep 30;139(1):136-145
references.pmid: 18472215
references.citation: AJNR Am J Neuroradiol. 1994 May;15(5):951-9
references.pmid: 8059666
references.citation: Cephalalgia. 2006 Aug;26(8):1025-7
references.pmid: 16886942
references.citation: Pain Physician. 2010 Jul-Aug;13(4):357-63
references.pmid: 20648204
references.citation: Pain Physician. 2012 May-Jun;15(3):203-12
references.pmid: 22622904
references.citation: Cephalalgia. 1987 Mar;7(1):21-7
references.pmid: 3495342
references.citation: Cochrane Database Syst Rev. 2005 Jul 20;(3):CD004001
references.pmid: 16034919
references.citation: Anesthesiology. 2001 Jul;95(1):72-80
references.pmid: 11465587
references.citation: J Neurosurg. 1990 Jun;72(6):866-71
references.pmid: 2338571
references.citation: Br J Neurosurg. 1994;8(5):567-71
references.pmid: 7857537
references.citation: Lancet Neurol. 2007 Apr;6(4):314-21
references.pmid: 17362835
references.citation: Arch Neurol. 1961 Aug;5:171-8
references.pmid: 13752662
references.citation: Headache. 2003 May;43(5):479-81
references.pmid: 12752753
references.citation: Pain. 1999 Feb;79(2-3):223-33
references.pmid: 10068168
references.citation: Curr Pain Headache Rep. 2001 Feb;5(1):83-91
references.pmid: 11252143
references.citation: Neuromodulation. 2003 Jan;6(1):20-6
references.pmid: 22150910
references.citation: Neurology. 2009 Jan 27;72(4):341-5
references.pmid: 19171831
references.citation: Headache. 2009 Jul;49(7):983-9
references.pmid: 19486173
references.citation: Headache. 2007 Feb;47(2):298-300
references.pmid: 17300376
references.citation: Spine (Phila Pa 1976). 1996 Jun 1;21(11):1344-50; discussion 1351
references.pmid: 8725927
references.citation: Neurology. 2003 Apr 22;60(8):1360-2
references.pmid: 12707445
references.citation: Lancet Neurol. 2006 Oct;5(10):873-7
references.pmid: 16987734
references.citation: Cephalalgia. 2008 Jul;28(7):787-97; discussion 798
references.pmid: 18547215
references.citation: Neuromodulation. 2013 Nov-Dec;16(6):557-62; discussion 563-4
references.pmid: 22882274
references.citation: Laryngoscope. 2006 Aug;116(8):1447-50
references.pmid: 16885751
references.citation: J Headache Pain. 2010 Feb;11(1):23-31
references.pmid: 19936616