title: Quality of life and emotional change for middle-aged and elderly patients with diabetic retinopathy.
abstract: OBJECTIVE
  To evaluate the SF-36, Diabetes Specificity Quality of Life Scale (DSQL) and anxiety and depression symptoms and investigate its changes in proliferative diabetic retinopathy (PDR) by vitrectomy interventions.
  
  
  METHODS
  The present study included 108 diabetic retinopathy (DR) patients: 54 with PDR and 54 with non-proliferative diabetic retinopathy (NPDR). Each healthy control group (n=54) sociodemographically matched to DR groups was established respectively. The quality of life, anxiety and depression symptoms were evaluated and analyzed on preoperative and postoperative month 1 using SF-36, DSQL and Hospital Anxiety and Depression Scale (HADS).
  
  
  RESULTS
  DR patients described impaired HRQL (Health Related Quality of life, SF-36) in 6 out of 8 subscales, including 'Body Health', 'Body Role Function', 'General Health', 'Society Function', 'Emotion Role Function' and 'Mental Health'. Compared with controls, DR patients (NPDR and PDR) suffered from statistically significantly impaired HRQL (SF-36 Summary score) (P<0.05). By surgical intervention, the anxiety and depression score were significantly reduced, while the health and quality of life (SF-36 Summary scores and DSQL scores) was improved in patients with PDR (P<0.05).
  
  
  CONCLUSIONS
  DR patients were affected in mentation and quality of life. Surgery interventions can improve SF-36, DSQL, anxiety and depression in PDR patients.
authors.affiliation: Department of Endocrinology, the First Affiliated Hospital, Medical College of Jinan University, Guangzhou 510632, Guangdong Province, China ; Department of Endocrinology, the Third Hospital of Nanchang, the Affiliated Nanchang Hospital of Southern Medical University, Nanchang 330009, Jiangxi Province, China.
authors.forename: Yao
authors.initials: Y
authors.lastname: Yu
authors.forename: Lie
authors.initials: L
authors.lastname: Feng
authors.forename: Yi
authors.initials: Y
authors.lastname: Shao
authors.forename: Ping
authors.initials: P
authors.lastname: Tu
authors.forename: He-Ping
authors.initials: HP
authors.lastname: Wu
authors.forename: Xun
authors.initials: X
authors.lastname: Ding
authors.forename: Wei-Hua
authors.initials: WH
authors.lastname: Xiao
keywords: SF-36; diabetes specificity quality of life scale; diabetic retinopathy; hospital anxiety and depression scale; vitrectomy
references.citation: J Int Med Res. 2009 Jul-Aug;37(4):1108-14
references.pmid: 19761693
references.citation: J Am Coll Cardiol. 2012 Apr 3;59(14):1295-301
references.pmid: 22464257
references.citation: Hong Kong Med J. 2005 Feb;11(1):20-9
references.pmid: 15687512
references.citation: Diabetes Care. 1997 Nov;20(11):1664-9
references.pmid: 9353605
references.citation: Psychiatry Clin Neurosci. 2009 Feb;63(1):65-72
references.pmid: 19067994
references.citation: N Engl J Med. 2010 Mar 25;362(12):1090-101
references.pmid: 20335585
references.citation: Transplant Proc. 2007 May;39(4):917-22
references.pmid: 17524850
references.citation: J Nurs Res. 2007 Sep;15(3):193-201
references.pmid: 17806036
references.citation: J AAPOS. 2005 Apr;9(2):148-51
references.pmid: 15838442
references.citation: Diabetologia. 2003 Sep;46(9):1190-8
references.pmid: 12879248