title: Detection of New Delhi metallo-β-lactamase (encoded by blaNDM-1) in Acinetobacter schindleri during routine surveillance.
abstract: A carbapenem-resistant Alcaligenes faecalis strain was isolated from a surveillance swab of a service member injured in Afghanistan. The isolate was positive for bla(NDM) by real-time PCR. Species identification was reevaluated on three identification systems but was inconclusive. Genome sequencing indicated that the closest relative was Acinetobacter schindleri and that bla(NDM-1) was carried on a plasmid that shared >99% identity with one identified in an Acinetobacter lwoffii isolate. The isolate also carried a novel chromosomally encoded class D oxacillinase.
authors.affiliation: Multidrug-resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA. patrick.t.mcgann4.ctr@mail.mil
authors.forename: Patrick
authors.initials: P
authors.lastname: McGann
authors.forename: Michael
authors.initials: M
authors.lastname: Milillo
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Clifford
authors.forename: Erik
authors.initials: E
authors.lastname: Snesrud
authors.forename: Lindsay
authors.initials: L
authors.lastname: Stevenson
authors.forename: Michael G
authors.initials: MG
authors.lastname: Backlund
authors.forename: Helen B
authors.initials: HB
authors.lastname: Viscount
authors.forename: Reyes
authors.initials: R
authors.lastname: Quintero
authors.forename: Yoon I
authors.initials: YI
authors.lastname: Kwak
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Zapor
authors.forename: Paige E
authors.initials: PE
authors.lastname: Waterman
authors.forename: Emil P
authors.initials: EP
authors.lastname: Lesho
mesh_terms: D000150:Acinetobacter / Q000201:enzymology* / Q000235:genetics* / Q000302:isolation & purification; D000151:Acinetobacter Infections / Q000382:microbiology; D000346:Afghanistan; D002876:Chromosomes, Bacterial; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D010957:Plasmids; D060888:Real-Time Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D004269:DNA, Bacterial; D001618:beta-Lactamases; C552864:beta-lactamase NDM-1
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