title: Improving of red colorants production by a new Penicillium purpurogenum strain in submerged culture and the effect of different parameters in their stability.
abstract: There is a worldwide interest in the development of processes for colorants production from natural sources such as microorganism. The aim of this study was to optimize red colorants production by Penicillium purpurogenum DPUA 1275 and to evaluate the effect of pH, temperature, salts and polymers on the stability of these colorants. Under optimized conditions, a 78% increase in red colorants production was achieved. The best pH and temperature conditions were obtained at pH 8.0 and 70°C, respectively. In the presence of salts NaCl and Na2 SO4 , both at concentrations of 0.1 and 0.5 M in Mcllvaine buffer (pH 8.0), the red colorants showed good stability. In the presence of both polymers polyethylene glycol and sodium polyacrylate, the red colorants kept their color intensity. Thus, this study presents characteristics of red colorants produced by P. purpurogenum that can be applied in different industries after toxicological examination.
authors.affiliation: Dept. of Biochemical and Pharmaceutical Technology, University of São Paulo, 05508-900, São Paulo, SP, Brazil. lelacarvalho21@usp.br
authors.forename: Valéria Carvalho
authors.initials: VC
authors.lastname: Santos-Ebinuma
authors.forename: Inês Conceição
authors.initials: IC
authors.lastname: Roberto
authors.forename: Maria Francisca
authors.initials: MF
authors.lastname: Simas Teixeira
authors.forename: Adalberto
authors.initials: A
authors.lastname: Pessoa
mesh_terms: D018929:Cell Culture Techniques / Q000379:methods*; D004355:Drug Stability; D006863:Hydrogen-Ion Concentration; D007218:Industrial Microbiology; D010407:Penicillium / Q000737:chemistry* / Q000166:cytology / Q000378:metabolism*; D010860:Pigments, Biological / Q000032:analysis / Q000737:chemistry* / Q000378:metabolism*; D012965:Sodium Chloride; D013431:Sulfates; D013696:Temperature
chemical_list: D010860:Pigments, Biological; D013431:Sulfates; C012036:sodium sulfate; D012965:Sodium Chloride