title: Genital prolapse repair with Avaulta Plus mesh: functional results and quality of life.
abstract: OBJECTIVE
  Evaluate anatomic and functional outcomes of genital prolapse repair by vaginal route using a mixed polypropylene and porcine skin mesh.
  
  
  METHODS
  Prospective pilot study from January 2009 to January 2011 in the gynecologic department of a tertiary university hospital. Twenty patients with stage II-III genital prolapse underwent anterior wall prolapse repair with anterior Avaulta Plus mesh. Functional results were evaluated using the pelvic floor distress inventory-short form (PFDI-20), the pelvic floor impact questionnaire-7 (PFIQ-7) and the Pelvic Organ Prolapse/Urinary Incontinence Sexual questionnaires (PISQ-12).
  
  
  RESULTS
  No per-operative complications occurred. One postoperative hematoma (5%) occurred requiring a second surgery. At a mean follow-up of 19.7 months, three patients had vaginal mesh exposure (15%) requiring a second surgery for two of them. Of the 20 women, 17 (85%) had optimal anatomic results and three (15%) had residual genital prolapse (Ba=-2 in two cases and Bp = -2 in the one). No recurrence was observed during the study period. A significant improvement in the PFDI-20 (P<0.001) and PFIQ-7 scores (P<0.001) was observed but no improvement in the PISQ-12 score.
  
  
  CONCLUSIONS
  In this series, we reported that genital prolapse repair using Avaulta Plus mesh resulted in a high success rate and improved quality of life but with an important prevalence of vaginal mesh exposure.
authors.affiliation: Department of obstetrics and gynecology, université Pierre et Marie Curie Paris VI, hôpital Tenon Paris, 4, rue de Chine, 75020 Paris, France. anne.thomin@tnn.aphp.fr
authors.forename: A
authors.initials: A
authors.lastname: Thomin
authors.forename: C
authors.initials: C
authors.lastname: Touboul
authors.forename: D
authors.initials: D
authors.lastname: Hequet
authors.forename: S
authors.initials: S
authors.lastname: Zilberman
authors.forename: M
authors.initials: M
authors.lastname: Ballester
authors.forename: E
authors.initials: E
authors.lastname: Daraï
mesh_terms: D000368:Aged; D001705:Bioprosthesis; D005260:Female; D006801:Humans; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D011126:Polypropylenes; D011446:Prospective Studies; D011474:Prosthesis Design; D011788:Quality of Life; D013526:Surgical Mesh
chemical_list: D011126:Polypropylenes