title: Treatment outcome monitoring of pulmonary tuberculosis cases notified in France in 2009.
abstract: The proportion of patients considered to be cured is a key indicator to assess national tuberculosis (TB) control. In France, TB treatment outcome monitoring was implemented in 2007. This article presents national results on treatment outcome among patients with pulmonary TB reported in France in 2009 and explores determinants of potentially unfavourable outcome. Information on treatment outcome was reported for 63% of eligible pulmonary cases of whom 70% had a successful outcome. In a multivariate analysis, potentially unfavourable outcome (17%), compared to treatment success, was significantly associated with being male, born abroad and having lived in France for less than 10 years, being in congregate settings when treatment was initiated, or having a previous history of anti-TB treatment. Enhanced awareness of treatment outcome monitoring is essential to improve the coverage and the quality of information. Earlier diagnosis and improved management of the disease in the elderly may reduce death due to TB. The high proportion of potentially unfavourable outcomes should be further investigated as they may require additional vigilance and/or actions in term of efforts of TB control in some population groups.
authors.affiliation: Institut de Veille Sanitaire, Saint Maurice cedex, France. d.antoine@invs.sante.fr
authors.forename: D
authors.initials: D
authors.lastname: Antoine
authors.forename: D
authors.initials: D
authors.lastname: Che
mesh_terms: D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use; D003627:Data Interpretation, Statistical; D018563:Disease Notification; D054242:Emigrants and Immigrants; D005260:Female; D005568:Forms and Records Control / Q000379:methods; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D019221:Mandatory Reporting; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D017063:Outcome Assessment, Health Care / Q000379:methods*; D011159:Population Surveillance; D016896:Treatment Outcome; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy*; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology / Q000401:mortality / Q000628:therapy*
chemical_list: D000995:Antitubercular Agents