title: Left ventricular hypertrophy amplifies the QT, and Tp-e intervals and the Tp-e/ QT ratio of left chest ECG.
abstract: OBJECTIVE
  To evaluate the changes in Tp-e interval (an interval from the peak to the end of the T wave), QT interval and Tp-e/QT ratio of the body surface ECG in patients with left ventricular hypertrophy (LVH).
  
  
  METHODS
  The Tp-e interval and QT interval were measured on body surface ECGs in 42 patients without either hypertension or LVH (control group), 41 patients having hypertension but not LVH (non-LVH group), and 38 patients with both hypertension and LVH (LVH group).
  
  
  RESULTS
  The mean corrected QT (QTc) interval, and mean corrected Tp-e[T(p-e)c] interval were significantly longer in the LVH group (0.430±0.021s vs. 0.409±0.019s, p < 0.01; 0.098±0.013s vs. 0.088±0.011s, respectively) than those in the control group. The Tp-e/QT ratio was also amplified in LVH group (0.232±0.028 vs.0.218±0.027) (p < 0.05).
  
  
  CONCLUSIONS
  LVH increased the QT interval, Tp-e interval and Tp-e/QT ratio of the body surface ECG.
authors.affiliation: Department of Cardiology, Key Laboratory of Environmental Genes Related to Diseases, Ministry of Education, the First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710061, China.
authors.forename: Zhao
authors.initials: Z
authors.lastname: Zhao
authors.forename: Zuyi
authors.initials: Z
authors.lastname: Yuan
authors.forename: Yuqiang
authors.initials: Y
authors.lastname: Ji
authors.forename: Yue
authors.initials: Y
authors.lastname: Wu
authors.forename: Yinzhi
authors.initials: Y
authors.lastname: Qi
keywords: QT interval; Tp-e interval; arrhythmia; hypertension; left ventricular hypertrophy
references.citation: Clin Sci (Lond). 2003 Dec;105(6):671-6
references.pmid: 12857349
references.citation: J Electrocardiol. 2008 Nov-Dec;41(6):567-74
references.pmid: 18790499
references.citation: Pharmacol Ther. 2008 Aug;119(2):141-51
references.pmid: 18423604
references.citation: JAMA. 2003 May 21;289(19):2560-72
references.pmid: 12748199
references.citation: Circulation. 1998 Nov 3;98(18):1928-36
references.pmid: 9799215
references.citation: Am J Hypertens. 2008 Jan;21(1):47-53
references.pmid: 18091743
references.citation: J Mol Cell Cardiol. 2008 Apr;44(4):633-46
references.pmid: 18336833
references.citation: J Physiol. 2007 May 15;581(Pt 1):277-89
references.pmid: 17331992
references.citation: J Electrocardiol. 2005 Oct;38(4 Suppl):154-8
references.pmid: 16226092
references.citation: Zhonghua Xin Xue Guan Bing Za Zhi. 2007 Jul;35(7):629-32
references.pmid: 17961428
references.citation: Clin Res Cardiol. 2009 Apr;98(4):208-12
references.pmid: 19031039
references.citation: Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H97-H104
references.pmid: 18441200
references.citation: J Am Coll Cardiol. 2009 Aug 4;54(6):505-12
references.pmid: 19643310
references.citation: Eur Heart J. 2008 Mar;29(6):741-7
references.pmid: 18204091
references.citation: J Biol Chem. 2008 Jul 18;283(29):20045-52
references.pmid: 18458081
references.citation: Heart Rhythm. 2006 Aug;3(8):948-56
references.pmid: 16876745
references.citation: Circ Res. 2008 Jun 6;102(11):1406-15
references.pmid: 18451341
references.citation: Hypertension. 2008 Apr;51(4):1109-14
references.pmid: 18259011
references.citation: J Cardiovasc Pharmacol. 2008 Apr;51(4):352-8
references.pmid: 18427277