title: Platelet counting.
abstract: Platelet counting is a daily basic hematological analysis of crucial interest in many clinical situations. Historical manual techniques (phase-contrast microscopy) have been replaced by automated techniques (impedance or optical analyzers) more rapid and precise. More recently, flow cytometry techniques using labeled monoclonal antibodies have been proposed as reference techniques. Nevertheless, pre-analytical and analytical variables should be respected to obtain reliable results and avoid validation pitfalls.
authors.affiliation: Hematology Department and Grand East Competence Center on Inherited Platelet Disorders, CHU Nancy, Nancy, France.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Salignac
authors.forename: Véronique
authors.initials: V
authors.lastname: Latger-Cannard
authors.forename: Nicole
authors.initials: N
authors.lastname: Schlegel
authors.forename: Thomas Pierre
authors.initials: TP
authors.lastname: Lecompte
mesh_terms: D001777:Blood Coagulation; D001780:Blood Coagulation Tests; D001792:Blood Platelets / Q000166:cytology*; D005434:Flow Cytometry; D006801:Humans; D010976:Platelet Count / Q000379:methods; D013921:Thrombocytopenia / Q000175:diagnosis; D013922:Thrombocytosis / Q000175:diagnosis