title: Clinical utilization of microembolus detection by transcranial Doppler sonography in intracranial stenosis-occlusive disease.
abstract: OBJECTIVE
  To discuss the clinical ultiliazation and significance of microembolus detection by transcranial Doppler (TCD) sonography in intracranial stenosis-occlusive disease.
  
  
  METHODS
  All related articles in this review were mainly searched from PubMed published in English from 1996 to 2012 using the terms of microembolic signal, transcranial Doppler, intracranial stenosis, stroke.
  
  
  METHODS
  Original articles and reviews were selected if they were related to the clinical utilization of microembolus detection in intracranial stenosis-occlusive disease.
  
  
  RESULTS
  Intracranial stenosis is a significant cause of cerebral emboli, and microembolus detection by TCD sonography were widely used in exploring the mechanisms of ischemic stroke with intracranial stenosis (including the middle cerebral artery stenosis and the vertebral-basilar stenosis), evaluating the prognosis of acute stroke, evaluating the therapeutic effects, and predicting the recurrent events of stroke.
  
  
  CONCLUSIONS
  Microembolus detection by TCD sonography plays an important role in the cerebral ischemic stroke patients with intracranial stenosis.
authors.affiliation: Department of Neurology, First Bethune Hospital of Jilin University, Changchun, Jilin 130021, China.
authors.forename: Xiu-Juan
authors.initials: XJ
authors.lastname: Wu
authors.forename: Ying-Qi
authors.initials: YQ
authors.lastname: Xing
authors.forename: Juan
authors.initials: J
authors.lastname: Wang
authors.forename: Kang-Ding
authors.initials: KD
authors.lastname: Liu
mesh_terms: D003251:Constriction, Pathologic / Q000000981:diagnostic imaging*; D006801:Humans; D020766:Intracranial Embolism / Q000000981:diagnostic imaging; D020521:Stroke / Q000000981:diagnostic imaging; D017585:Ultrasonography, Doppler, Transcranial / Q000379:methods*