title: Muco-submucosal elongated polyps of the gastrointestinal tract: a case series and a review of the literature.
abstract: We present three cases of gastrointestinal muco-submucosal elongated polyps, two located in the duodenum and one in the descending colon. All three cases had a characteristic, "worm-like" endoscopic appearance and were lined by unremarkable mucosa. The vascular component was located in the submucosa and was composed of a mixture of variably dilated blood vessels (capillaries and veins) and lymphatics. The duodenal polyps displayed lipomatous metaplasia of the submucosal stroma. The dual vascular phenotype of the vascular component was confirmed by immunohistochemistry with D2-40 and CD31.
authors.affiliation: Department of Pathology, National University Hospital System, Singapore 119074, Singapore.
authors.forename: Char Loo
authors.initials: CL
authors.lastname: Tan
authors.forename: Sze Hwa
authors.initials: SH
authors.lastname: Tan
authors.forename: Jimmy B Y
authors.initials: JB
authors.lastname: So
authors.forename: Fredrik
authors.initials: F
authors.lastname: Petersson
mesh_terms: D000368:Aged; D058846:Antibodies, Monoclonal, Murine-Derived; D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D003106:Colon / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D003111:Colonic Polyps / Q000473:pathology; D004386:Duodenum / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D016145:Endoscopy, Digestive System; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007413:Intestinal Mucosa / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D007417:Intestinal Polyps / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D010641:Phenotype; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000032:analysis; D011237:Predictive Value of Tests
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; D015415:Biomarkers; D019408:Platelet Endothelial Cell Adhesion Molecule-1; C500987:monoclonal antibody D2-40
keywords: Angioma; Endoscopic ultrasonography; Endoscopy; Muco-submucosal elongated polyp; Vascular malformation
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