title: Miniprobe endoscopic ultrasonography has limitations in determining the T stage in early colorectal cancer.
abstract: OBJECTIVE
  Mini-probe endoscopic ultrasonography (mEUS) is a useful diagnostic tool for accurate assessment of tumor invasion. The aim of this study was to estimate the accuracy of mEUS in patients with early colorectal cancer (ECC).
  
  
  METHODS
  Ninety lesions of ECC underwent mEUS for pre-treatment staging. We divided the lesions into either the mucosal group or the submucosal group according to the mEUS findings. The histological results of the specimens were compared with the mEUS findings.
  
  
  RESULTS
  The overall accuracy for assessing the depth of tumor invasion (T stage) was 84.4% (76/90). The accuracy of mEUS was significantly lower for submucosal lesions compared to mucosal lesions (p=0.003) and it was lower for large tumors (≥2 cm) (p=0.034). The odds ratios of large tumors and submucosal tumors affecting the accuracy of T staging were 3.46 (95% confidence interval [CI], 1.05 to 11.39) and 6.25 (95% CI, 1.85 to 25.14), respectively. When submucosal tumors were combined with large size, the odds ratio was 14.67 (95% CI, 1.46 to 146.96).
  
  
  CONCLUSIONS
  The overall accuracy of T stage determination with mEUS was considerably high in patients with ECC; however, the accuracy decreased when tumor size was >2 cm or the tumor had invaded the submucosal layer.
authors.affiliation: Department of Internal Medicine, Inje University Seoul Paik Hospital, Inje University College of Medicine, Seoul, Korea.
authors.forename: Pei Chuan
authors.initials: PC
authors.lastname: Tsung
authors.forename: Jong Hyeok
authors.initials: JH
authors.lastname: Park
authors.forename: You Sun
authors.initials: YS
authors.lastname: Kim
authors.forename: Sun Young
authors.initials: SY
authors.lastname: Kim
authors.forename: Won Wo
authors.initials: WW
authors.lastname: Park
authors.forename: Hyun Tae
authors.initials: HT
authors.lastname: Kim
authors.forename: Jin Nam
authors.initials: JN
authors.lastname: Kim
authors.forename: Yun Kyung
authors.initials: YK
authors.lastname: Kang
authors.forename: Jeong Seop
authors.initials: JS
authors.lastname: Moon
keywords: Colorectal neoplasms; Endosonography
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