title: Creep and fatigue behavior of a novel 2-component paste-like formulation of acrylic bone cements.
abstract: The fatigue and creep performance of two novel acrylic bone cement formulations (one bone cement without antibiotics, one with antibiotics) was compared to the performance of clinically used bone cements (Osteopal V, Palacos R, Simplex P, SmartSet GHV, Palacos R+G and CMW1 with Gentamicin). The preparation of the novel bone cement formulations involves the mixing of two paste-like substances in a static mixer integrated into the cartridge which is used to apply the bone cement. The fatigue performance of the two novel bone cement formulations is comparable to the performance of the reference bone cements. The creep compliance of the bone cements is significantly influenced by the effects of physical ageing. The model parameters of Struik's creep law are used to compare the creep behavior of different bone cements. The novel 2-component paste-like bone cement formulations are in the group of bone cements which exhibit a higher creep resistance.
authors.affiliation: Biomedical Materials and Implants Group, Fraunhofer Institute for Mechanics of Materials IWM, Wöhlerstraße 11, 79108 Freiburg, Germany.
authors.forename: Ulrike
authors.initials: U
authors.lastname: Köster
authors.forename: Raimund
authors.initials: R
authors.lastname: Jaeger
authors.forename: Mareike
authors.initials: M
authors.lastname: Bardts
authors.forename: Christian
authors.initials: C
authors.lastname: Wahnes
authors.forename: Hubert
authors.initials: H
authors.lastname: Büchner
authors.forename: Klaus-Dieter
authors.initials: KD
authors.lastname: Kühn
authors.forename: Sebastian
authors.initials: S
authors.lastname: Vogt
mesh_terms: D004339:Drug Compounding / Q000379:methods; D055119:Elastic Modulus; D006244:Hardness; D008422:Materials Testing; D009824:Ointments / Q000737:chemistry; D019904:Polymethyl Methacrylate / Q000737:chemistry*; D013718:Tensile Strength; D014783:Viscosity
chemical_list: D009824:Ointments; D019904:Polymethyl Methacrylate
references.citation: J Bone Joint Surg Br. 1992 Sep;74(5):652-8
references.pmid: 1527108
references.citation: Acta Biomater. 2009 Feb;5(2):719-26
references.pmid: 18835229
references.citation: J Mater Sci Mater Med. 2006 May;17(5):421-6
references.pmid: 16688582
references.citation: J Appl Biomater. 1994;5(3):235-43
references.pmid: 10147450
references.citation: Spine (Phila Pa 1976). 2012 Apr 1;37(7):544-50
references.pmid: 21738093
references.citation: J Mater Sci Mater Med. 1998 Dec;9(12):707-9
references.pmid: 15348926
references.citation: J Mater Sci Mater Med. 2003 Apr;14(4):321-5
references.pmid: 15348456
references.citation: Biomed Tech (Berl). 2004 Mar;49(3):61-5
references.pmid: 15106900
references.citation: Biomaterials. 1994 Sep;15(11):875-81
references.pmid: 7833433
references.citation: J Biomed Mater Res. 1990 Feb;24(2):135-54
references.pmid: 2329111
references.citation: J Biomech. 2001 Jul;34(7):873-81
references.pmid: 11410171
references.citation: Biomaterials. 2003 Jan;24(2):239-45
references.pmid: 12419624
references.citation: Acta Biomater. 2010 Mar;6(3):943-52
references.pmid: 19766742
references.citation: Biomaterials. 1993 Dec;14(15):1165-72
references.pmid: 8130322
references.citation: Acta Orthop Scand. 1995 Jun;66(3):207-14
references.pmid: 7604698
references.citation: Biomaterials. 2005 Jun;26(17):3713-8
references.pmid: 15621261
references.citation: J Biomech. 2004 Oct;37(10):1505-12
references.pmid: 15336925
references.citation: J Arthroplasty. 2001 Oct;16(7):811-9
references.pmid: 11607895
references.citation: J Bone Joint Surg Am. 2002;84-A Suppl 2:2-20
references.pmid: 12479335
references.citation: Clin Mater. 1993;12(2):95-102
references.pmid: 10148336
references.citation: Clin Orthop Relat Res. 1997 Jul;(340):118-29
references.pmid: 9224247
references.citation: J Biomed Mater Res. 2000 Sep;53(5):498-504
references.pmid: 10984697
references.citation: J Biomed Mater Res. 1997 Summer;38(2):155-82
references.pmid: 9178743
references.citation: J Mater Sci Mater Med. 2007 Sep;18(9):1849-58
references.pmid: 17492254
references.citation: J Biomech. 2007;40(7):1525-33
references.pmid: 17070816
references.citation: Biomaterials. 2009 Oct;30(31):6309-17
references.pmid: 19699519
references.citation: J Arthroplasty. 2000 Feb;15(2):205-9
references.pmid: 10708087
references.citation: J Mater Sci Mater Med. 2001 Aug;12(8):707-17
references.pmid: 15348243
references.citation: Acta Orthop Scand. 1996 Dec;67(6):593-8
references.pmid: 9065074
references.citation: Biomaterials. 2005 Sep;26(27):5532-41
references.pmid: 15860209
references.citation: Biomaterials. 1982 Apr;3(2):93-6
references.pmid: 7082743
references.citation: J Bone Joint Surg Br. 1997 Jul;79(4):665-9
references.pmid: 9250762
references.citation: J Biomed Mater Res. 1981 Mar;15(2):159-82
references.pmid: 7348711
references.citation: Biomaterials. 2003 Mar;24(6):1023-31
references.pmid: 12504524
references.citation: J Biomed Mater Res B Appl Biomater. 2009 Nov;91(2):910-7
references.pmid: 19630059