title: Differences in movement-related cortical activation patterns underlying motor performance in children with and without developmental coordination disorder.
abstract: Behavioral deficits in visuomotor planning and control exhibited by children with developmental coordination disorder (DCD) have been extensively reported. Although these functional impairments are thought to result from "atypical brain development," very few studies to date have identified potential neurological mechanisms. To address this knowledge gap, electroencephalography (EEG) was recorded from 6- to 12-yr-old children with and without DCD (n = 14 and 20, respectively) during the performance of a visuomotor drawing task. With respect to motor performance, typically developing (TD) children exhibited age-related improvements in key aspects of motor planning and control. Although some children with DCD performed outside this TD landscape (i.e., age-related changes within the TD group), the group developmental trajectory of the children with DCD was similar to that of the TD children. Despite overall similarities in performance, engagement of cortical resources in the children with DCD was markedly different from that in their TD counterparts. While the patterns of activation are stable in TD children across the age range, the young children with DCD exhibited less engagement of motor cortical brain areas and the older children with DCD exhibited greater engagement of motor cortical brain areas than their TD peers. These results suggest that older children with DCD may employ a compensatory strategy in which increased engagement of relevant motor resources allows these children to perform comparably to their TD peers. Moreover, the magnitude of activation was related to several kinematic measures, particularly in children with DCD, suggesting that greater engagement in motor resources may underlie better behavioral performance.
authors.affiliation: Neuroscience and Cognitive Science Program and Department of Kinesiology, University of Maryland, College Park, MD, USA. mpangelinan@research.baycrest.org
authors.forename: Melissa M
authors.initials: MM
authors.lastname: Pangelinan
authors.forename: Bradley D
authors.initials: BD
authors.lastname: Hatfield
authors.forename: Jane E
authors.initials: JE
authors.lastname: Clark
mesh_terms: D000367:Age Factors; D001696:Biomechanical Phenomena; D058256:Brain Waves; D016022:Case-Control Studies; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009044:Motor Cortex / Q000254:growth & development / Q000503:physiopathology*; D009048:Motor Skills; D019957:Motor Skills Disorders / Q000503:physiopathology*; D009068:Movement / Q000502:physiology*; D013647:Task Performance and Analysis
keywords: EEG; atypical development; development; spectral power
references.citation: Electroencephalogr Clin Neurophysiol. 1989 Mar;72(3):250-8
references.pmid: 2465128
references.citation: J Clin Neurophysiol. 1989 Jan;6(1):75-84
references.pmid: 2915031
references.citation: Cereb Cortex. 2011 Apr;21(4):737-47
references.pmid: 20805237
references.citation: Dev Psychobiol. 2003 Jul;43(1):44-56
references.pmid: 12794778
references.citation: Res Dev Disabil. 2011 Jul-Aug;32(4):1388-98
references.pmid: 21277739
references.citation: Brain. 1995 Aug;118 ( Pt 4):913-33
references.pmid: 7655888
references.citation: Pediatrics. 2010 Sep;126(3):e678-86
references.pmid: 20713484
references.citation: Ann N Y Acad Sci. 1984;425:489-95
references.pmid: 6588870
references.citation: Neuroimage. 2002 Feb;15(2):373-85
references.pmid: 11798272
references.citation: Brain Cogn. 2011 Apr;75(3):232-41
references.pmid: 21256656
references.citation: Neuroimage. 2005 Oct 1;27(4):737-52
references.pmid: 16027009
references.citation: Psychophysiology. 2011 Jun;48(6):813-24
references.pmid: 20964696
references.citation: J Neurophysiol. 1996 Jan;75(1):233-47
references.pmid: 8822554
references.citation: Dev Med Child Neurol. 2012 Oct;54(10):932-7
references.pmid: 22803701
references.citation: Exp Brain Res. 2008 Dec;191(4):403-18
references.pmid: 18709366
references.citation: Med Sci Sports Exerc. 2004 Jan;36(1):118-29
references.pmid: 14707777
references.citation: J Learn Disabil. 1990 Jun-Jul;23(6):375-85
references.pmid: 2366044
references.citation: Neuroimage. 1999 Dec;10(6):682-94
references.pmid: 10600414
references.citation: J Neurophysiol. 1999 Jun;81(6):3065-77
references.pmid: 10368421
references.citation: Neuroimage. 2004 Mar;21(3):936-45
references.pmid: 15006660
references.citation: Neuroimage. 2002 Sep;17(1):161-73
references.pmid: 12482074
references.citation: Hum Mov Sci. 2003 Nov;22(4-5):413-31
references.pmid: 14624826
references.citation: Electroencephalogr Clin Neurophysiol. 1983 Oct;56(4):373-83
references.pmid: 6193951
references.citation: Hum Mov Sci. 2006 Oct;25(4-5):622-33
references.pmid: 17011655
references.citation: Int J Psychophysiol. 2001 Dec;43(1):41-58
references.pmid: 11742684
references.citation: J Clin Neurophysiol. 2004 May-Jun;21(3):144-56
references.pmid: 15375345
references.citation: Electroencephalogr Clin Neurophysiol. 1998 Feb;109(1):50-62
references.pmid: 11003064
references.citation: Exp Brain Res. 2011 Jul;212(2):257-65
references.pmid: 21584627
references.citation: Hum Mov Sci. 2003 Nov;22(4-5):495-513
references.pmid: 14624830
references.citation: J Child Psychol Psychiatry. 1997 Nov;38(8):1023-37
references.pmid: 9413800
references.citation: Motor Control. 2004 Oct;8(4):450-60
references.pmid: 15585900
references.citation: Brain. 1998 Aug;121 ( Pt 8):1513-31
references.pmid: 9712013
references.citation: Neuroimage. 2003 Sep;20(1):404-12
references.pmid: 14527600
references.citation: J Neurosci Methods. 2004 Mar 15;134(1):9-21
references.pmid: 15102499