title: Status of carotid intima-media thickness and associated risk factors in diabetic, prediabetic and non-diabetic acute stroke.
abstract: OBJECTIVE
  Measure carotid intima-medial thickness (CIMT), its variability, risk factors, their correlation, in type 2 diabetic (DM), pre-diabetic (PDM) and non-diabetic (NDM) acute strokes.
  
  
  METHODS
  Twenty four DM and a matched population of 14 patients each of PDM and NDM strokes were studied. Each group was compared as whole and by gender and stroke segregation. Study parameters were right and left CIMTs (CIMTR, CIMTL), insulin resistance (IR), age, BMI and lipids, correlations between CIMTs and CIMTs with risk markers.
  
  
  RESULTS
  CIMTR was higher in DM and PDM compared to NDM, but CIMTLs did not differ. CIMTs were similar in genders and stroke types of each group. The IR was significantly high only in DM. Age and BMI correlations were predominantly positive and lipids variable except in PDM. Age and IR had better impacts on CIMTs in DM while BMI was poor. Females and infarcts had a more congruous CIMT increment in DM and PDM but male and haemorrhage in NDM.
  
  
  CONCLUSIONS
  With similar levels of risk markers, their impacts on the CIMTs are highly variable at various levels of glycaemia. CIMTs were similar in the genders and stroke types of each group, irrespective of the glycemic status. The pre-diabetes group had distinct features.
authors.affiliation: NRS Medical College, Kolkata, West Bengal.
authors.forename: Uday Sankar
authors.initials: US
authors.lastname: Ghosh
authors.forename: Partha
authors.initials: P
authors.lastname: Chattopadhyay
authors.forename: Samar
authors.initials: S
authors.lastname: Banerjee
authors.forename: Madan
authors.initials: M
authors.lastname: Karmakar
authors.forename: Suchit
authors.initials: S
authors.lastname: Majumder
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology; D059168:Carotid Intima-Media Thickness; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D011236:Prediabetic State / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology; D011237:Predictive Value of Tests; D012307:Risk Factors; D020521:Stroke / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D018608:Ultrasonography, Doppler
chemical_list: D015415:Biomarkers; D001786:Blood Glucose