title: [Meta analysis of efficacy and safety between mammotome minimally invasive operation and open excision for benign breast tumor].
abstract: OBJECTIVE
  To compare the efficacy and safety between mammotome minimally invasive operation and conventional open excision for benign breast tumor.
  
  
  METHODS
  A computer-based online search of Medline, PubMed, Embase, Ovid, Cochrane Library, VIP, Wanfang, CNKI and Chinese Biological Medicine Database was performed, and conference references were manually searched. With the Cochrane Collaboration Guidelines, all randomized controlled trials comparing mammotome minimally invasive operation and conventional open excision were systematically reviewed. The Cochrane Collaboration's RevMan 5.0 software was used for data analysis.
  
  
  RESULTS
  A total of 15 studies involving 5256 patients was included. Meta-analyses showed no significant difference in the size of tumor, postoperative hematomas, ecchymosis, ecchymoma and residual disease between mammotome minimally invasive operation and conventional open excision. Mammotome minimally invasive operation was superior to open excision as to the size of incision, intraoperative blood loss, surgical duration, healing time, size of scar, wound infection and breast deformation.
  
  
  CONCLUSIONS
  Mammotome minimally invasive surgery is an ideal method for benign breast tumor.
authors.affiliation: General Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China.
authors.forename: Boni
authors.initials: B
authors.lastname: Ding
authors.forename: Daojin
authors.initials: D
authors.lastname: Chen
authors.forename: Xiaorong
authors.initials: X
authors.lastname: Li
authors.forename: Hongyan
authors.initials: H
authors.lastname: Zhang
authors.forename: Yujun
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D000328:Adult; D001941:Breast Diseases / Q000473:pathology / Q000601:surgery*; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D005348:Fibrocystic Breast Disease / Q000473:pathology / Q000601:surgery; D006801:Humans; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D016032:Randomized Controlled Trials as Topic; D018084:Ultrasonography, Interventional; D014618:Vacuum; D055815:Young Adult