title: Transfusion reaction in a case with the rare Bombay blood group.
abstract: Bombay phenotype is extremely rare in Caucasian with an incidence of 1 in 250,000. When individuals with the Bombay phenotype need blood transfusion, they can receive only autologous blood or blood from another Bombay blood group. Transfusing blood group O red cells to them can cause a fatal hemolytic transfusion reaction. In this study, we report a case with the rare Bombay blood group that was misdiagnosed as the O blood group and developed a hemolytic transfusion reaction. This highlights the importance of both forward and reverse typing in ABO blood grouping and standard cross-matching and performing standard pretransfusion laboratory tests in hospital blood banks.
authors.affiliation: Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.
authors.forename: Hayedeh Javadzadeh
authors.initials: HJ
authors.lastname: Shahshahani
authors.forename: Mohamad Reza
authors.initials: MR
authors.lastname: Vahidfar
authors.forename: Seyed Ali
authors.initials: SA
authors.lastname: Khodaie
keywords: ABO blood-group system; Bombay phenotype; blood group incompatibility; blood transfusion; transfusion reaction
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