title: [Salivary duct carcinoma: report of 6 cases and review of the literature].
abstract: OBJECTIVE
  To summarize the clinicopathologic characteristics, treatment and prognosis of salivary duct carcinoma.
  
  
  METHODS
  Six cases of salivary duct carcinoma treated in our hospital were reported. And the literatures were reviewed. All cases were proved by operation and pathology. The clinical characteristics, histological features, therapeutic method and prognosis were analyzed.
  
  
  RESULTS
  Salivary duct carcinoma predominantly influenced old male patients and mainly occurred in the parotid gland. Physical examination revealed a firm, immobile and poorly defined mass accompanied by nerve infiltrated symptom. The histological appearance was characterized by solid cell nests with ductal structures and central comedonecrosis. Treatment required extensive resection and radical neck dissection with postoperative radiotherapy. The clinical course was marked by development of both local disease recurrence as well as cervical lymph node and distant metastasis.
  
  
  CONCLUSIONS
  Salivary duct carcinoma is a rare malignant salivary tumour with poor prognosis. Extensive resection is the key to improve the survival rate.
authors.affiliation: Dental Center, Lishui Central Hospital, the Fifth Affiliated Hospital of Wenzhou Medical College, Lishui 323000, Zhejiang Province, China. ywcls@sina.com
authors.forename: Wen-cheng
authors.initials: WC
authors.lastname: Ye
authors.forename: Ying
authors.initials: Y
authors.lastname: Li
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell; D006258:Head and Neck Neoplasms; D006801:Humans; D008297:Male; D037981:Neck Dissection; D010306:Parotid Gland; D011379:Prognosis; D018987:Salivary Ducts; D012468:Salivary Gland Neoplasms; D000077195:Squamous Cell Carcinoma of Head and Neck