title: Alternative sigma factor SigK has a role in stress tolerance of group I Clostridium botulinum strain ATCC 3502.
abstract: The role of the alternative sigma factor SigK in cold and osmotic stress tolerance of Clostridium botulinum ATCC 3502 was demonstrated by induction of sigK after temperature downshift and exposure to hyperosmotic conditions and by impaired growth of the sigK mutants under the respective conditions.
authors.affiliation: Department of Food Hygiene and Environmental Health, University of Helsinki, Helsinki, Finland. elias.dahlsten@helsinki.fi
authors.forename: Elias
authors.initials: E
authors.lastname: Dahlsten
authors.forename: David
authors.initials: D
authors.lastname: Kirk
authors.forename: Miia
authors.initials: M
authors.lastname: Lindström
authors.forename: Hannu
authors.initials: H
authors.lastname: Korkeala
mesh_terms: D000064:Acclimatization / Q000502:physiology*; D003014:Clostridium botulinum / Q000254:growth & development* / Q000378:metabolism; D003080:Cold Temperature; D017931:DNA Primers / Q000235:genetics; D059022:Food Safety / Q000379:methods*; D009997:Osmotic Pressure; D020133:Reverse Transcriptase Polymerase Chain Reaction; D013312:Stress, Physiological / Q000502:physiology*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D017931:DNA Primers; D014157:Transcription Factors; C084190:sigma K
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