title: [Association of carotid intima media thickness with blood pressure and HDL cholesterol in children].
abstract: BACKGROUND
  Cardiovascular risk factors must be controlled since childhood.
  
  
  OBJECTIVE
  To assess the association of carotid intima media thickness (CIMT) with the components of the metabolic syndrome in Children.
  
  
  METHODS
  Cross sectional assessment of 299 children aged 11.5 ± 0.9 years (58% women) with and without metabolic syndrome components. Anthropometric parameters and blood pressure were measured and a blood sample was obtained to measure blood glucose and lipids. CIMT was measured using high resolution ultrasound.
  
  
  RESULTS
  Ninety three percent of children were post puberal, 64% were overweight and 25% had metabolic syndrome. Mean and maximum CIMT correlated with systolic blood pressure (r = 0.21 and 0.21 respectively p < 0.01). Children with a CIMT over the 75th percentile had higher blood pressure and lower HDL cholesterol. A stepwise logistic regression accepted both variables as predictors of CIMT with odds ratios for mean CIMT of 1.46 (1.19-1-79) and 0.81 (0.7-0.94) per five units of change, respectively.
  
  
  CONCLUSIONS
  In this group of children systolic blood pressure and HDL cholesterol are associated to CIMT.
authors.affiliation: Pediatría, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
authors.forename: Pilar
authors.initials: P
authors.lastname: Arnaiz
authors.forename: Luis
authors.initials: L
authors.lastname: Villarroel
authors.forename: Salesa
authors.initials: S
authors.lastname: Barja
authors.forename: Iván
authors.initials: I
authors.lastname: Godoy
authors.forename: Berta
authors.initials: B
authors.lastname: Cassis
authors.forename: Angélica
authors.initials: A
authors.lastname: Domínguez
authors.forename: Oscar
authors.initials: O
authors.lastname: Castillo
authors.forename: Marcelo
authors.initials: M
authors.lastname: Farías
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Carvajal
authors.forename: Ana Cristina
authors.initials: AC
authors.lastname: Tinoco
authors.forename: Francisco
authors.initials: F
authors.lastname: Mardones
mesh_terms: D000293:Adolescent; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000209:etiology*; D059168:Carotid Intima-Media Thickness; D002648:Child; D002677:Chile / Q000453:epidemiology; D008076:Cholesterol, HDL / Q000097:blood*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications*; D009765:Obesity / Q000150:complications / Q000453:epidemiology; D016017:Odds Ratio; D012307:Risk Factors; D013599:Systole
chemical_list: D008076:Cholesterol, HDL