title: Measuring health-related quality of life among adults in Singapore: population norms for the EQ-5D.
abstract: OBJECTIVE
  To provide population norms for the Euro-QoL-5D (EQ-5D) according to age, sex, ethnicity and language version using a representative sample of adults aged 18 years and above in the Singapore population.
  
  
  METHODS
  A total of 5,594 respondents who completed the self-administrated paper-based EQ-5D in the Singapore Mental Health Study were included in this study. Socio-demographic characteristics were captured using a structured questionnaire.
  
  
  RESULTS
  The mean age of the sample was 40 years, females comprised 52.2 % of the sample and 78 % were of Chinese descent. Pain/discomfort was the most frequently reported problem (15.3 %) followed by anxiety/depression (8.2 %), whilst self-care (0.5 %) was the least frequently reported problem in the Singapore population. Multiple linear regression analysis revealed that younger age, higher income, those employed and those administered English version of the questionnaire were significantly associated with higher EQ-5D index.
  
  
  CONCLUSIONS
  This article provides important population norms for the EQ-5D for measuring health-related quality of life (HRQOL) both in clinical settings and in the research context. Our results suggest that socio-demographic factors should be taken into account when assessing HRQOL among adults in Singapore.
authors.affiliation: Research Division, Institute of Mental Health, Singapore, Singapore, edimansyah_abdin@imh.com.sg.
authors.forename: Edimansyah
authors.initials: E
authors.lastname: Abdin
authors.forename: Mythily
authors.initials: M
authors.lastname: Subramaniam
authors.forename: Janhavi Ajit
authors.initials: JA
authors.lastname: Vaingankar
authors.forename: Nan
authors.initials: N
authors.lastname: Luo
authors.forename: Siow Ann
authors.initials: SA
authors.lastname: Chong
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D044466:Asian People / Q000523:psychology; D005260:Female; D006306:Health Surveys; D006801:Humans; D007802:Language; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D015999:Multivariate Analysis; D010146:Pain / Q000523:psychology*; D011159:Population Surveillance; D011788:Quality of Life; D012044:Regression Analysis; D012648:Self Care; D017678:Sex Distribution; D012846:Singapore / Q000453:epidemiology; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D055815:Young Adult
references.citation: Med Care. 2009 Jan;47(1):53-60
references.pmid: 19106731
references.citation: Value Health. 2008 Dec;11(7):1162-9
references.pmid: 18489492
references.citation: Health Place. 2011 Mar;17(2):671-80
references.pmid: 21334961
references.citation: Ann Acad Med Singap. 2010 Feb;39(2):129-35
references.pmid: 20237735
references.citation: Value Health. 2009 Nov-Dec;12 Suppl 3:S106-9
references.pmid: 20586970
references.citation: Qual Life Res. 2003 Feb;12(1):87-92
references.pmid: 12625521
references.citation: Int J Methods Psychiatr Res. 2012 Jun;21(2):149-57
references.pmid: 22331628
references.citation: Qual Life Res. 2011 Apr;20(3):309-20
references.pmid: 21042861
references.citation: Lancet. 2006 May 27;367(9524):1747-57
references.pmid: 16731270
references.citation: Health Policy. 1990 Dec;16(3):199-208
references.pmid: 10109801
references.citation: Epilepsy Res. 2001 May;45(1-3):101-3; discussion 105-7
references.pmid: 11461807
references.citation: BMJ. 1998 Mar 7;316(7133):736-41
references.pmid: 9529408
references.citation: Med Decis Making. 2011 Nov-Dec;31(6):790-9
references.pmid: 22067429
references.citation: Hepatology. 2008 Apr;47(4):1108-17
references.pmid: 18318043
references.citation: Qual Life Res. 2010 May;19(4):565-9
references.pmid: 20204708
references.citation: Ann Acad Med Singap. 2011 Jun;40(6):276-86
references.pmid: 21779616
references.citation: Med Decis Making. 2011 Nov-Dec;31(6):787-9
references.pmid: 22067428
references.citation: Health Qual Life Outcomes. 2003 Apr 17;1:7
references.pmid: 12756060
references.citation: Ann Acad Med Singap. 2007 Jun;36(6):403-8
references.pmid: 17597964
references.citation: Pol Arch Med Wewn. 2010 Jul;120(7-8):276-81
references.pmid: 20693958
references.citation: Value Health. 2010 Aug;13(5):631-5
references.pmid: 20412541
references.citation: Qual Life Res. 1993 Jun;2(3):169-80
references.pmid: 8401453
references.citation: Scand J Public Health. 2009 Jul;37(5):467-74
references.pmid: 19535407
references.citation: Qual Life Res. 1998 Feb;7(2):155-66
references.pmid: 9523497
references.citation: Ann Acad Med Singap. 2009 Jun;38(6):521-8
references.pmid: 19565103
references.citation: Med Care. 2007 Dec;45(12):1162-70
references.pmid: 18007166
references.citation: Stat Med. 1998 Aug 15-30;17(15-16):1703-14
references.pmid: 9749441
references.citation: Health Econ. 2002 Jun;11(4):341-53
references.pmid: 12007165
references.citation: Med J Aust. 1998 Feb 16;168(4):178-82
references.pmid: 9507716
references.citation: J Clin Epidemiol. 2009 Feb;62(2):206-13
references.pmid: 18619790
references.citation: Ann Acad Med Singap. 2003 Sep;32(5):685-90
references.pmid: 14626802
references.citation: Med Care. 2005 Nov;43(11):1078-86
references.pmid: 16224300
references.citation: Value Health. 2010 Dec;13(8):873-8
references.pmid: 20667055
references.citation: Qual Life Res. 2001;10(7):621-35
references.pmid: 11822795
references.citation: Exp Aging Res. 1999 Oct-Dec;25(4):471-5
references.pmid: 10553532
references.citation: Med Care. 1997 Nov;35(11):1095-108
references.pmid: 9366889
references.citation: Qual Life Res. 2005 Dec;14(10):2187-96
references.pmid: 16328899