title: [Translational research in anesthesiology: preface and comments].
abstract: According to Wikipedia, translational research is scientific research that facilitates the translation of findings from basic science to practical applications that enhance human health and well-being. In this special issue, the topic of translational research in anesthesiology was featured. Six subtopics including 1) adaptation of induced pluripotent stem (iPS) cells to central nerve injury, 2) signaling of granulocyte macrophage colony stimulating factor and its clinical application: host-defense and organ protection, 3) molecular mechanisms of chronic pain and its therapeutic strategy, 4) endoplasmic reticulum stress and opioid tolerance, 5) relationships of damage-associated molecular patterns and organ injury, and 6) translational research in omics science to clinical anesthesia, are presented and discussed in detail. Anesthesiologists always keep in mind that the goal of translational research is to improve our health through research and that there would be no bright future in anesthesiology without the fruits of translational research.
authors.affiliation: International University of Health and Welfare, Clinical Medicine Research Center Kaken Hospital, Ichikawa 272-0827.
authors.forename: Takashi
authors.initials: T
authors.lastname: Nishino
mesh_terms: D000776:Anesthesiology; D057170:Translational Research, Biomedical