title: Dispersion-cancelled biological imaging with quantum-inspired interferometry.
abstract: Quantum information science promises transformative impact over a range of key technologies in computing, communication, and sensing. A prominent example uses entangled photons to overcome the resolution-degrading effects of dispersion in the medical-imaging technology, optical coherence tomography. The quantum solution introduces new challenges: inherently low signal and artifacts, additional unwanted signal features. It has recently been shown that entanglement is not a requirement for automatic dispersion cancellation. Such classical techniques could solve the low-signal problem, however they all still suffer from artifacts. Here, we introduce a method of chirped-pulse interferometry based on shaped laser pulses, and use it to produce artifact-free, high-resolution, dispersion-cancelled images of the internal structure of a biological sample. Our work fulfills one of the promises of quantum technologies: automatic-dispersion-cancellation interferometry in biomedical imaging. It also shows how subtle differences between a quantum technique and its classical analogue may have unforeseen, yet beneficial, consequences.
authors.affiliation: Institute for Quantum Computing and Department of Physics & Astronomy, University of Waterloo, Waterloo ON N2L 3G, CANADA.
authors.forename: M D
authors.initials: MD
authors.lastname: Mazurek
authors.forename: K M
authors.initials: KM
authors.lastname: Schreiter
authors.forename: R
authors.initials: R
authors.lastname: Prevedel
authors.forename: R
authors.initials: R
authors.lastname: Kaltenbaek
authors.forename: K J
authors.initials: KJ
authors.lastname: Resch
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D007089:Image Enhancement / Q000295:instrumentation*; D007368:Interferometry / Q000295:instrumentation*; D009391:Nephelometry and Turbidimetry / Q000295:instrumentation*; D011789:Quantum Theory; D012031:Refractometry / Q000295:instrumentation*
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