title: Roles of NLRP10 in innate and adaptive immunity.
abstract: Mammalian nucleotide-binding domain leucine-rich repeat containing proteins (NLRs) are important pattern-recognition receptors, still the function of many NLRs remains poorly defined. Here we review first insights into the molecular function of NLRP10 highlighting the role of this specific NLR in innate and adaptive immune responses.
authors.affiliation: Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, 50931 Cologne, Germany.
authors.forename: Anna
authors.initials: A
authors.lastname: Damm
authors.forename: Katja
authors.initials: K
authors.lastname: Lautz
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Kufer
mesh_terms: D056704:Adaptive Immunity; D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D051017:Apoptosis Regulatory Proteins / Q000276:immunology* / Q000378:metabolism*; D002352:Carrier Proteins / Q000276:immunology* / Q000378:metabolism*; D006801:Humans; D007113:Immunity, Innate; D007249:Inflammation / Q000276:immunology / Q000378:metabolism; D051379:Mice
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D051017:Apoptosis Regulatory Proteins; D002352:Carrier Proteins; C494352:NLRP10 protein, human; C572764:NLRP10 protein, mouse