title: [Impact of sleeve gastrectomy with ileal interposition duodenojejunal bypass operation on lipid metabolism in non-obese type 2 diabetes mellitus patients].
abstract: OBJECTIVE
  To evaluate the effect of sleeve gastrectomy with ileal interposition duodenojejunal bypass operation on lipid metabolism in non-obese type 2 diabetes mellitus patients.
  
  
  METHODS
  Twenty-nine non-obese patients with type 2 diabetes mellitus underwent sleeve gastrectomy with ileal interposition duodenojejunal bypass operation. All the patients were subjected to the measurement of total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL), low density lipoprotein (LDL), homeostatic model assessment for insulin resistance (Homa-IR), glycosylated hemoglobin (HbA1c) at postoperative 12th month.
  
  
  RESULTS
  Twelve months after ileal interposition duodenojejunal bypass operation, the blood glucose was controlled without taking hypoglycemic drugs in 28 patients (96.5%) and HbA1c decreased from (8.4±1.3)% to (6.5±1.6)% (P<0.01). Dyslipidemia were corrected in 25 cases (86.2%). TC became normal in 84.2% (15/19), and TG became normal in 82.3% (14/17). HDL became normal in 66.6% (8/12). LDL became normal in 31.2% (5/16). TC/HDL ratio decreased from 5.6±1.2 to 2.8±1.0 (P<0.01). TG/HDL ratio decreased from 3.2±1.3 to 1.5±0.8 (all P<0.01).
  
  
  CONCLUSIONS
  Sleeve gastrectomy with ileal interposition duodenojejunal bypass is an effective operation for the correction of dyslipidemia in non-obese patients with type 2 diabetes mellitus.
authors.affiliation: Department of General Surgery, The Central Hospital of Panzhihua City, Sichuan Panzhihua 617067, China. yy_hong@sina.com
authors.forename: Ying-hong
authors.initials: YH
authors.lastname: Yang
authors.forename: Jing
authors.initials: J
authors.lastname: Yan
authors.forename: Yan-jun
authors.initials: YJ
authors.lastname: Wu
authors.forename: Yuan
authors.initials: Y
authors.lastname: Lin
authors.forename: Xiao-lin
authors.initials: XL
authors.lastname: Yue
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism / Q000601:surgery*; D050171:Dyslipidemias / Q000601:surgery; D005260:Female; D005743:Gastrectomy; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D007581:Jejunoileal Bypass / Q000379:methods*; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D009765:Obesity; D012189:Retrospective Studies; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D002784:Cholesterol; D006442:Glycated Hemoglobin; D014280:Triglycerides; C517652:hemoglobin A1c protein, human