title: The influence of depression on physical complications in spinal cord injury: behavioral mechanisms and health-care implications.
abstract: METHODS
  This study is a literature review and a proposed conceptual model.
  
  
  OBJECTIVE
  The objective of this study is to develop a conceptual model to explore the relationship between the presence of depressive symptoms and secondary physical complications such as pressure ulcers, urinary tract infections and autonomic dysreflexia in spinal cord injury (SCI).
  
  
  METHODS
  Community setting for individuals with SCI.
  
  
  METHODS
  A conceptual model explaining the mechanism underlying the relationship between depression and secondary physical SCI complications was developed based on the International Classification of Functioning, Disability and Health (ICF). A literature review was conducted to develop the model and to identify potential mechanisms responsible for the association.
  
  
  RESULTS
  A conceptual model based on ICF was created, informed by the literature discussing the link between depression and secondary physical SCI complications. Evidence in the literature was located that supports both a causal connection between depression and increased physical complications and/or the potential mechanisms mediating that connection.
  
  
  CONCLUSIONS
  The proposed model can be utilized to encourage further research on the influence of depression on SCI outcomes and the importance of prompt and effective identification and treatment of depressive symptoms. Additional research is needed to assess the relationship between depression and secondary physical SCI complications, and to test the validity of the model.
authors.affiliation: UBC School of Population and Public Health, The Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
authors.forename: H
authors.initials: H
authors.lastname: Krueger
authors.forename: V K
authors.initials: VK
authors.lastname: Noonan
authors.forename: D
authors.initials: D
authors.lastname: Williams
authors.forename: L M
authors.initials: LM
authors.lastname: Trenaman
authors.forename: C S
authors.initials: CS
authors.lastname: Rivers
mesh_terms: D001342:Autonomic Nervous System Diseases / Q000209:etiology*; D003863:Depression / Q000209:etiology*; D006233:Persons with Disabilities; D006801:Humans; D008962:Models, Theoretical; D003668:Pressure Ulcer / Q000209:etiology*; D013119:Spinal Cord Injuries / Q000150:complications*; D014552:Urinary Tract Infections / Q000209:etiology*