title: [The management of prostate cancer: a retrospective chart review in 808 French men undergoing biopsy].
abstract: OBJECTIVE
  We explored the characteristics of a sample of men who had undergone a biopsy in clinical practice in France and evaluated initial treatment choice in men with a positive biopsy.
  
  
  METHODS
  This was a multi-centre, retrospective chart review including men who had undergone a biopsy in France. Clinical variables were collected using an electronic data capture system.
  
  
  RESULTS
  Eight hundred and eight men were included; 632 men (78%) had an initial biopsy and 176 men (22%) had one or more repeat biopsy. The mean age was 64 years and 9% of men were 75 years or more. The mean (median) PSA was 11.6 (7.0) ng/mL; 25% of men had a PSA greater than 10 ng/mL. Twenty-eight percent of men had a suspicious DRE. A total of 52% of men had a positive initial and 26% a positive repeat biopsy. One hundred and eleven patients (34%) had low-risk PCa (stage T1c-2a, PSA<10 ng/mL, Gleason sum<7) and 195 (59%) were at intermediate/high risk of disease progression. The most common treatment was radical therapy (54% of patients), even in men with low-risk PCa (40% of patients). A total of 38% of low-risk patients chose active surveillance.
  
  
  CONCLUSIONS
  The French biopsy sample appeared to be at a relatively high risk of having PCa at initial biopsy. Radical therapy was the most common treatment choice in men with a positive biopsy. In patients with low-risk PCa, radical therapy and active surveillance were used most often and to the same extent.
authors.affiliation: Service d'urologie, CHU hôpital Tenon, AP-HP, 4, rue de la Chine, 75970 Paris cedex 20, France. olivier.cussenot@tnn.aphp.fr
authors.forename: O
authors.initials: O
authors.lastname: Cussenot
authors.forename: F
authors.initials: F
authors.lastname: Rozet
authors.forename: A
authors.initials: A
authors.lastname: Ruffion
authors.forename: N
authors.initials: N
authors.lastname: Mottet
authors.forename: B
authors.initials: B
authors.lastname: Bordier
authors.forename: B
authors.initials: B
authors.lastname: Malavaud
authors.forename: B
authors.initials: B
authors.lastname: Meesen
authors.forename: H
authors.initials: H
authors.lastname: Stoevelaar
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000473:pathology / Q000628:therapy*; D012189:Retrospective Studies