title: [Antihistamine drugs, quinuclidine derivatives, in allergic diseases. What is their benefit?].
abstract: The extensive rise in the prevalence of allergic diseases (AD), which among the planet's population is now 15 to 30% or more, occupies the great attention of different specialists' to the mechanisms for the development and control of the symptoms of allergy. In view of the most important role of histamine in the pathogenesis of allergic diseases, antihistamines are first-line line drugs in the pharmacotherapy of AD. Quinuclidine derivatives that combine the most useful properties of the first and second generations occupy a special place among histamines. The paper gives the data of clinical trials of the efficacy of the antihistamines quinuclidine derivatives in the treatment of various allergic diseases.
authors.forename: L V
authors.initials: LV
authors.lastname: Luss
authors.forename: N V
authors.initials: NV
authors.lastname: Shartanova
mesh_terms: D000818:Animals; D006633:Histamine Antagonists / Q000627:therapeutic use*; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy*; D011812:Quinuclidines / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D006633:Histamine Antagonists; D011812:Quinuclidines