title: Prosthetic valve endocarditis and bloodstream infection due to Mycobacterium chimaera.
abstract: Prosthetic valve endocarditis (PVE) due to fast-growing nontuberculous mycobacteria (NTM) has been reported anecdotally. Reports of PVE with slowly growing NTM, however, are lacking. We present here one case of PVE and one case of bloodstream infection caused by Mycobacterium chimaera. Randomly amplified polymorphic DNA (RAPD)-PCR indicated a relatedness of the two M. chimaera strains. Both patients had heart surgery 2 years apart from each other. A nosocomial link was not detected.
authors.affiliation: Division of Infectious Diseases and Hospital Epidemiology, University and University Hospital Zurich, Zurich, Switzerland.
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Achermann
authors.forename: Matthias
authors.initials: M
authors.lastname: Rössle
authors.forename: Matthias
authors.initials: M
authors.lastname: Hoffmann
authors.forename: Vanessa
authors.initials: V
authors.lastname: Deggim
authors.forename: Stefan
authors.initials: S
authors.lastname: Kuster
authors.forename: Dieter R
authors.initials: DR
authors.lastname: Zimmermann
authors.forename: Guido
authors.initials: G
authors.lastname: Bloemberg
authors.forename: Michael
authors.initials: M
authors.lastname: Hombach
authors.forename: Barbara
authors.initials: B
authors.lastname: Hasse
mesh_terms: D004269:DNA, Bacterial / Q000235:genetics; D004697:Endocarditis, Bacterial / Q000175:diagnosis* / Q000382:microbiology; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D058889:Molecular Typing; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000382:microbiology; D009170:Nontuberculous Mycobacteria / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D016459:Prosthesis-Related Infections / Q000175:diagnosis* / Q000382:microbiology; D019105:Random Amplified Polymorphic DNA Technique
chemical_list: D004269:DNA, Bacterial
references.citation: Int J Syst Evol Microbiol. 2004 Jul;54(Pt 4):1277-1285
references.pmid: 15280303
references.citation: Am J Respir Crit Care Med. 2007 Feb 15;175(4):367-416
references.pmid: 17277290
references.citation: J Heart Valve Dis. 1992 Sep;1(1):102-9
references.pmid: 1341213
references.citation: JAMA. 2007 Mar 28;297(12):1354-61
references.pmid: 17392239
references.citation: Ann Thorac Surg. 1985 Mar;39(3):277-9
references.pmid: 3977472
references.citation: Clin Infect Dis. 1997 May;24(5):884-8
references.pmid: 9142787
references.citation: J Gen Appl Microbiol. 2007 Apr;53(2):153-7
references.pmid: 17575455
references.citation: Curr Infect Dis Rep. 2010 Jul;12(4):257-65
references.pmid: 21308540
references.citation: J Antimicrob Chemother. 2012 Jan;67(1):154-8
references.pmid: 21965431
references.citation: Diagn Microbiol Infect Dis. 1997 Apr;27(4):147-50
references.pmid: 9154411
references.citation: Emerg Infect Dis. 2008 Sep;14(9):1443-6
references.pmid: 18760016
references.citation: J Clin Microbiol. 2006 Apr;44(4):1359-66
references.pmid: 16597863
references.citation: J Clin Microbiol. 1997 Dec;35(12):3132-9
references.pmid: 9399508