title: The relationship between serum calcium level, blood lipids, and blood pressure in hypertensive and normotensive subjects who come from a normal university in east of China.
abstract: Previous studies revealed that low calcium intake is related to high prevalence of cardiovascular diseases such as hypertension. However, the relationship between serum calcium and blood pressure was unclear. The prevalence of hypertension is high in China. Thus, the aim of this study was to evaluate the serum calcium level between hypertensive and normotensive groups and to investigate the correlation between serum calcium, blood pressure, and blood lipid parameters. A total of 1,135 adult subjects participated in this study and were divide into two study groups: a hypertensive group (n = 316) who had 140 mmHg or higher in systolic blood pressure (SBP) or 90 mmHg or higher in diastolic blood pressure (DBP) and an age- and sex-matched normotensive group (n = 819, 120 mmHg or less SBP and 80 mmHg or less DBP). Our results indicate a significant trend for men (60 years old or older) in the direction of decreasing blood pressure with increasing serum calcium level, but no trend for women was indicated. In the normotensive group, a significant positive correlation was found between DBP and total cholesterol (P < 0.01) and triglyceride (P < 0.01), Likewise, triglyceride was positively correlated with SBP (P < 0.01). Overall, these data suggest that serum calcium may have an influence in the blood pressure of older male subjects with hypertension and in blood lipid profiles of normotensive subjects.
authors.affiliation: Department of Preventive Medicine, Wannan Medical College, No. 22 Road West Wenchang, Yijiang District, Wuhu 241002, People's Republic of China. yingshuiyao@163.com
authors.forename: Yingshui
authors.initials: Y
authors.lastname: Yao
authors.forename: Lianping
authors.initials: L
authors.lastname: He
authors.forename: Yuelong
authors.initials: Y
authors.lastname: Jin
authors.forename: Yan
authors.initials: Y
authors.lastname: Chen
authors.forename: Hui
authors.initials: H
authors.lastname: Tang
authors.forename: Xiuli
authors.initials: X
authors.lastname: Song
authors.forename: Lingling
authors.initials: L
authors.lastname: Ding
authors.forename: Qin
authors.initials: Q
authors.lastname: Qi
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Huang
authors.forename: Quanhai
authors.initials: Q
authors.lastname: Wang
authors.forename: Jiegen
authors.initials: J
authors.lastname: Yu
mesh_terms: D000368:Aged; D001794:Blood Pressure; D002118:Calcium / Q000097:blood*; D002681:China; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000503:physiopathology; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014495:Universities
chemical_list: D008055:Lipids; D002118:Calcium