title: Difference in clinical and angiographic characteristics of very late stent thrombosis between drug-eluting and bare-metal stent implantations.
abstract: BACKGROUND
  Limited data are available with which to compare the clinical characteristics of patients with very late stent thrombosis (VLST) after drug-eluting stent (DES) or bare-metal stent (BMS) implantation. The purpose of this study was to investigate the differences in the characteristics of VLST after DES and BMS implantation by reviewing the clinical and angiographic data.
  
  
  RESULTS
  A total of 28 patients (30 lesions) with VLST after DES implantation and 33 patients (33 lesions) with VLST after BMS implantation were identified. The occurrence of VLST after BMS implantation (2,647±996 days) was much later than that after DES implantation (1,194±558 days, P<0.001). The number of VLST after DES implantation increased gradually each year; however VLST after BMS implantation started to occur >50 months later, and its number increased subsequently. The prevalence of VLST related to surgical procedures involving discontinuation of antiplatelet therapy in VLST patients was higher after DES implantation (14.3%) than after BMS implantation (0%, P=0.039). Angiographic stent fracture was seen in 36.7% of VLST lesions after DES implantation at different times (464-2,102 days after procedure), while none was seen in VLST lesions after BMS implantation (P<0.001).
  
  
  CONCLUSIONS
  The timing of VLST was different after DES and BMS implantation. Stent fracture was a specific finding of VLST after DES implantation.
authors.affiliation: Department of Cardiology, Kurashiki Central Hospital, Kurashiki 710-8602, Japan. daba-kuboshun101@hotmail.co.jp
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Kubo
authors.forename: Kazushige
authors.initials: K
authors.lastname: Kadota
authors.forename: Masatomo
authors.initials: M
authors.lastname: Ozaki
authors.forename: Tahei
authors.initials: T
authors.lastname: Ichinohe
authors.forename: Haruki
authors.initials: H
authors.lastname: Eguchi
authors.forename: Koshi
authors.initials: K
authors.lastname: Miyake
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Hyodo
authors.forename: Naoki
authors.initials: N
authors.lastname: Saito
authors.forename: Hideaki
authors.initials: H
authors.lastname: Otsuji
authors.forename: Suguru
authors.initials: S
authors.lastname: Otsuru
authors.forename: Daiji
authors.initials: D
authors.lastname: Hasegawa
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Shigemoto
authors.forename: Seiji
authors.initials: S
authors.lastname: Habara
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tada
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Tanaka
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Fuku
authors.forename: Harumi
authors.initials: H
authors.lastname: Katoh
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Satoki
authors.initials: S
authors.lastname: Fujii
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Goto
authors.forename: Kazuaki
authors.initials: K
authors.lastname: Mitsudo
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015425:Myocardial Reperfusion; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage; D015995:Prevalence; D011475:Prosthesis Failure / Q000009:adverse effects*; D012189:Retrospective Studies; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology / Q000601:surgery; D013997:Time Factors
chemical_list: D010975:Platelet Aggregation Inhibitors