title: Acrodysostosis and spinal canal involvement.
abstract: BACKGROUND
  Acrodysostosis is a rare syndrome characterized by peripheral dysostosis, nasal hypoplasia, and frequently mental retardation. Only two adult cases of acrodysostosis have been reported to have neurological symptoms.
  
  
  METHODS
  We report one additional adult case that presented with signs of spinal cord compression from spinal stenosis, and make the first histologic description in the literature of the bony anomalies seen in acrodysostosis. The patient had a T3 to T5 laminectomy and experienced a complete recovery.
  
  
  CONCLUSIONS
  Special attention should be given to these patients to detect signs of spinal stenosis, as early decompression can lead to neurological recovery.
authors.affiliation: Department of Neurosurgery, Division of Spine Surgery, Paris Descartes University and Sainte-Anne University Hospital, Paris, France.
authors.forename: Georges Abi
authors.initials: GA
authors.lastname: Lahoud
authors.affiliation: Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania, USA.
authors.forename: Nohra
authors.initials: N
authors.lastname: Chalouhi
authors.affiliation: Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania, USA. Electronic address: pascal.jabbour@jefferson.edu.
authors.forename: Pascal
authors.initials: P
authors.lastname: Jabbour
mesh_terms: D019299:Decompression, Surgical / Q000379:methods*; D004413:Dysostoses / Q000150:complications* / Q000601:surgery*; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications* / Q000601:surgery*; D007796:Laminectomy; D009460:Neurologic Examination; D019635:Neurosurgical Procedures / Q000379:methods*; D010009:Osteochondrodysplasias / Q000150:complications* / Q000601:surgery*; D020127:Recovery of Function; D013115:Spinal Canal / Q000473:pathology / Q000601:surgery*; D013117:Spinal Cord Compression / Q000209:etiology; D013122:Spinal Diseases / Q000150:complications* / Q000601:surgery*; D013130:Spinal Stenosis / Q000209:etiology; D016896:Treatment Outcome; D055815:Young Adult
keywords: Acrodysostosis; Spinal cord compression; Spinal stenosis