title: [Mitral regurgitation and coronary stenosis in postmyocardial infarction patients].
abstract: The results of investigations devoted to relationship of mitral regurgitation (MR) and scars are contradictive, data on relationship of MR and localization of coronary lesions are few. Purpose. To determinate relationship of moderate or severe MR to localization of coronary stenosis in postmyocardial infarction patients. Methods. There were 1167 patients with no MR and 403 patients with moderate or severe MR. Results. Patients with MR had more severe New York Heart Association (NYHA) functional class (III-IV) (35.5 vs. 11.2%). Echocardiographic indices of left atrial dimension (23.5+/-2.9 vs. 20.3+/-2.1 mm/m) and extent of left ventricular (LV) wall motion abnormalities (32.8+/-14.9 vs. 23.6+/-12.7%) were higher in patients with MR as well as reduced LV systolic function (LV ejection fraction &lt;50% - 63.7 vs. 25.6%) and LV dilatation (63.3 vs. 19.9%, all p&lt;0.001). Rates of multivessel coronary artery involvement (three or more arteries) (27.5 vs. 18.3%, p=0.001), lesions in left main coronary artery (7.2 vs. 1.1%), circumflex (36.2 vs. 26.7), and right coronary artery (57.3 vs. 44.9%) were higher in patients with MR (all p&lt;0.001). According to results of multivariate analysis MR was independently associated with LV dilatation, NYHA class of congestive heart failure, index of left atrial size, and extent of LV wall motion abnormalities. Moderate or severe chronic MR was not related to localization of coronary stenosis in these patients.
authors.forename: E I
authors.initials: EI
authors.lastname: Iaroslavskaia
authors.forename: V A
authors.initials: VA
authors.lastname: Kuznetsov
authors.forename: G S
authors.initials: GS
authors.lastname: Pushkarev
authors.forename: D V
authors.initials: DV
authors.lastname: Krinochkin
authors.forename: I P
authors.initials: IP
authors.lastname: Zyrianov
authors.forename: G V
authors.initials: GV
authors.lastname: Kolunin
mesh_terms: D000328:Adult; D017023:Coronary Angiography / Q000379:methods / Q000706:statistics & numerical data; D023921:Coronary Stenosis / Q000150:complications / Q000175:diagnosis; D004452:Echocardiography / Q000379:methods; D005260:Female; D006325:Heart Atria / Q000473:pathology / Q000503:physiopathology; D006333:Heart Failure / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000503:physiopathology; D015999:Multivariate Analysis; D009203:Myocardial Infarction / Q000150:complications* / Q000453:epidemiology; D012042:Registries; D012307:Risk Factors; D012720:Severity of Illness Index; D013223:Statistics as Topic; D016277:Ventricular Function, Left