title: Public health implications from COGS and potential for risk stratification and screening.
abstract: The PHG Foundation led a multidisciplinary program, which used results from COGS research identifying genetic variants associated with breast, ovarian and prostate cancers to model risk-stratified prevention for breast and prostate cancers. Implementing such strategies would require attention to the use and storage of genetic information, the development of risk assessment tools, new protocols for consent and programs of professional education and public engagement.
authors.affiliation: PHG Foundation (Foundation for Genomics and Population Health), Cambridge, UK. hilary.burton@phgfoundation.org
authors.forename: Hilary
authors.initials: H
authors.lastname: Burton
authors.forename: Susmita
authors.initials: S
authors.lastname: Chowdhury
authors.forename: Tom
authors.initials: T
authors.lastname: Dent
authors.forename: Alison
authors.initials: A
authors.lastname: Hall
authors.forename: Nora
authors.initials: N
authors.lastname: Pashayan
authors.forename: Paul
authors.initials: P
authors.lastname: Pharoah
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000235:genetics; D003299:Cooperative Behavior; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D008297:Male; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000235:genetics; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000235:genetics; D011634:Public Health; D018570:Risk Assessment
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