title: Multiplexed ionic current sensing with glass nanopores.
abstract: We report a method for simultaneous ionic current measurements of single molecules across up to 16 solid state nanopore channels. Each device, costing less than $20, contains 16 glass nanopores made by laser assisted capillary pulling. We demonstrate simultaneous multichannel detection of double stranded DNA and trapping of DNA origami nanostructures to form hybrid nanopores.
authors.affiliation: Cavendish Laboratory, Cambridge, United Kingdom.
authors.forename: Nicholas A W
authors.initials: NA
authors.lastname: Bell
authors.forename: Vivek V
authors.initials: VV
authors.lastname: Thacker
authors.forename: Silvia
authors.initials: S
authors.lastname: Hernández-Ainsa
authors.forename: Maria E
authors.initials: ME
authors.lastname: Fuentes-Perez
authors.forename: Fernando
authors.initials: F
authors.lastname: Moreno-Herrero
authors.forename: Tim
authors.initials: T
authors.lastname: Liedl
authors.forename: Ulrich F
authors.initials: UF
authors.lastname: Keyser
mesh_terms: D004247:DNA / Q000032:analysis / Q000737:chemistry; D004553:Electric Conductivity; D004566:Electrodes; D005898:Glass / Q000737:chemistry*; D007477:Ions / Q000737:chemistry; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation; D058608:Nanopores; D049329:Nanostructures / Q000737:chemistry
chemical_list: D007477:Ions; D004247:DNA