title: Synovial sarcoma mechanisms: a series of unfortunate events.
abstract: Human synovial sarcoma is caused by a chromosome translocation, which fuses DNA encoding SSX to that encoding the SS18 protein. Kadoch and Crabtree now show that the resulting cellular transformation stems from disruption of the normal architecture and function of the human SWI/SNF (BAF) complex.
authors.affiliation: Cancer Research UK, London Research Institute, Clare Hall Laboratories, Blanche Lane, South Mimms, Hertfordshire EN6 3LD, UK. j.svejstrup@cancer.org.uk
authors.forename: Jesper Q
authors.initials: JQ
authors.lastname: Svejstrup