title: Ionizing radiation exposure and the development of intervertebral disc degeneration--no case to answer.
abstract: In the following perspective article, Mellor and Breen provide a counterpoint to a previous perspective on the potential link between ionizing radiation exposure and intervertebral disc degeneration in humans [1]. The previous perspective asked, is this link a myth or reality? It suggested the potential for such a link. Mellor and Breen offer a drastically alternate view, in essence, that the question itself is flawed. To support their perspective, they explain the different units of radiation measurement and their conversion to risk in humans and how this impacts the previous perspective. They explain the variable sensitivity of different body tissues to radiation and highlight that neither human research nor any of the multiple international regulatory agencies have ever suggested that the intervertebral disc is sensitive to radiation. Finally, they claim that it is impossible to predict with any certainty the effects of low-level radiation on the intervertebral discs.
authors.affiliation: Institute for Musculoskeletal Research and Clinical Implementation, Anglo-European College of Chiropractic, 13-15 Parkwood Rd, Bournemouth, BH5 2DF, United Kingdom. imrci.fmellor@aecc.ac.uk
authors.forename: Fiona E
authors.initials: FE
authors.lastname: Mellor
authors.forename: Alexander C
authors.initials: AC
authors.lastname: Breen
mesh_terms: D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000209:etiology*; D011832:Radiation Injuries / Q000150:complications*