title: Renal support in acute kidney injury.
abstract: Acute kidney injury requiring renal replacement therapy (RRT) is associated with an unacceptably high mortality rate. Despite the identification of the modality, timing and intensity of dialysis, membrane biocompatibility, hollow fiber and catheter properties as potential modifying factors, there is little convincing evidence for the superiority of one over the other. However, the available data suggest that the early initiation of RRT may be beneficial. A focused review of clinical trials and meta-analysis of clinical trials of RRT is provided.
authors.affiliation: Department of Clinical Sciences, University of Central Florida, Orlando, FL, USA.
authors.forename: A
authors.initials: A
authors.lastname: Asmar
authors.forename: S
authors.initials: S
authors.lastname: Iqbal
authors.forename: R
authors.initials: R
authors.lastname: Mohandas
authors.forename: N I
authors.initials: NI
authors.lastname: Ejaz
authors.forename: M
authors.initials: M
authors.lastname: Shimada
authors.forename: N
authors.initials: N
authors.lastname: Maroz
authors.forename: B
authors.initials: B
authors.lastname: Dass
authors.forename: A Ahsan
authors.initials: AA
authors.lastname: Ejaz
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology / Q000628:therapy*; D001672:Biocompatible Materials; D002315:Cardiopulmonary Bypass; D004231:Diuresis; D006440:Hemofiltration / Q000009:adverse effects / Q000379:methods; D006801:Humans; D019586:Intracranial Hypertension / Q000209:etiology / Q000517:prevention & control; D008567:Membranes, Artificial; D015201:Meta-Analysis as Topic; D015337:Multicenter Studies as Topic / Q000706:statistics & numerical data; D010530:Peritoneal Dialysis / Q000295:instrumentation / Q000379:methods; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data; D006435:Renal Dialysis / Q000295:instrumentation / Q000379:methods; D017582:Renal Replacement Therapy / Q000379:methods; D012189:Retrospective Studies; D016896:Treatment Outcome; D014883:Water-Electrolyte Imbalance / Q000209:etiology
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial