title: Thrombotic thrombocytopenic purpura in the first trimester of pregnancy.
abstract: Thrombotic thrombocytopenic purpura (TTP) occurs more commonly in women and so can be associated with pregnancy. The time during pregnancy with greatest risk for development of TTP is near term and during the post partum period. TTP occurring in early trimester is uncommon and is also associated with great maternal and fetal mortality. We report a successful outcome of pregnancy in a woman with TTP in early first trimester who was treated with therapeutic plasma exchange.
authors.affiliation: Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Pooja
authors.initials: P
authors.lastname: Sikka
authors.forename: Seema
authors.initials: S
authors.lastname: Chopra
authors.forename: Neelam
authors.initials: N
authors.lastname: Aggarwal
authors.forename: Vanita
authors.initials: V
authors.lastname: Suri
authors.forename: Abi
authors.initials: A
authors.lastname: Chandrasekaran
keywords: First trimester; plasmapheresis; pregnancy; thrombotic thrombocytopenic purpura
references.citation: Curr Opin Hematol. 2003 Sep;10(5):339-44
references.pmid: 12913787
references.citation: Br J Haematol. 2003 Feb;120(4):556-73
references.pmid: 12588343
references.citation: Eur J Obstet Gynecol Reprod Biol. 2003 Dec 10;111(2):146-52
references.pmid: 14597242
references.citation: J Clin Apher. 2001;16(4):202-9
references.pmid: 11835417
references.citation: Ann Hematol. 1992 May;64(5):245-8
references.pmid: 1623060
references.citation: Vox Sang. 2004 Nov;87(4):287-90
references.pmid: 15585025
references.citation: Blood Purif. 1995;13(5):271-82
references.pmid: 7546529
references.citation: J Clin Apher. 2004;19(1):5-10
references.pmid: 15095395