title: Vertebral arteriovenous fistulae (AVF) in neurofibromatosis type 1: a report of two cases.
abstract: Spontaneous vertebral arteriovenous fistulae (AVF) associated with neurofibromatosis Type 1 (NF-1) is a rare occurrence in the previous reports. We presented two female NF-1 patients with a diagnosis of cervical vertebral AVF treated with endovascular approach. The fistula in the first case was successfully obliterated by feeder occlusion; whereas, for the second one, new fistulae were formed following the primary fistula closure. Anatomic and hemodynamic changes in combination with dysplastic vascular condition in NF-1 may contribute to fistulae formation de novo. The present case points out a rare challenge encountered in the treatment of vertebral arteriovenous fistula complicated by previous fistula obliteration in NF-1.
authors.affiliation: Xuanwu Hospital, Capital University of Medical Sciences, Department of Neurosurgery, Beijing, P.R. China.
authors.forename: Peng
authors.initials: P
authors.lastname: Gao
authors.forename: Yanfei
authors.initials: Y
authors.lastname: Chen
authors.forename: Hongqi
authors.initials: H
authors.lastname: Zhang
authors.forename: Peng
authors.initials: P
authors.lastname: Zhang
authors.forename: Feng
authors.initials: F
authors.lastname: Ling
mesh_terms: D001164:Arteriovenous Fistula / Q000209:etiology* / Q000473:pathology / Q000628:therapy*; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009456:Neurofibromatosis 1 / Q000150:complications*; D014711:Vertebral Artery / Q000002:abnormalities* / Q000601:surgery*; D055815:Young Adult