title: Anti-Bredt N-heterocyclic carbene: an efficient ligand for the gold(I)-catalyzed hydroamination of terminal alkynes with parent hydrazine.
abstract: An anti-Bredt N-heterocyclic carbene gold(I) chloride complex was synthesized by taking advantage of the reversible insertion of the free carbene into the NH bond of hexamethyldisilazane. This precatalyst promotes the parent hydrazine hydroamination of terminal alkynes at room temperature.
authors.affiliation: UCSD-CNRS Joint Research Laboratory (UMI 3555), Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0343, USA.
authors.forename: María J
authors.initials: MJ
authors.lastname: López-Gómez
authors.forename: David
authors.initials: D
authors.lastname: Martin
authors.forename: Guy
authors.initials: G
authors.lastname: Bertrand
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D000586:Amination; D002384:Catalysis; D018360:Crystallography, X-Ray; D006046:Gold / Q000737:chemistry*; D006571:Heterocyclic Compounds / Q000737:chemistry*; D006834:Hydrazines / Q000737:chemistry*; D008024:Ligands; D008697:Methane / Q000031:analogs & derivatives* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D050607:Organogold Compounds / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D000480:Alkynes; D006571:Heterocyclic Compounds; D006834:Hydrazines; D008024:Ligands; D050607:Organogold Compounds; C030011:carbene; C029424:hydrazine; D006046:Gold; D008697:Methane