title: New findings in genodermatoses.
abstract: New technologies are accelerating the pace at which genetic defects leading to inherited skin disease are elucidated. Translation of these genetic discoveries into new therapies for patients with inherited skin diseases has not been as rapid but the pace is now accelerating. This article summarizes recent findings in genetic skin diseases, the scope of advances being made, the role of new DNA analysis technologies in these discoveries, as well as highlighting some examples of how an understanding of the genetic cause of inherited skin diseases can lead to therapeutic interventions for patients.
authors.affiliation: Department of Dermatology, University of Missouri, 1 Hospital Drive, Room MA111D, Columbia, MO 65212, USA. dyerja@health.missouri.edu
authors.forename: Jonathan A
authors.initials: JA
authors.lastname: Dyer
mesh_terms: D003879:Dermatologic Agents / Q000627:therapeutic use*; D005820:Genetic Testing; D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D017422:Sequence Analysis, DNA / Q000379:methods*; D012873:Skin Diseases, Genetic / Q000235:genetics* / Q000628:therapy
chemical_list: D003879:Dermatologic Agents