title: [Clinical analysis of 1059 patients with taste disorders].
abstract: Taste disorders are caused by several factors, and there have been few reports concerning the clinical course of taste disorders. In this study, patients with taste disorders were classified into 10 groups according to causes, and they were retrospectively studied in terms of therapeutic effects. In total, 1059 patients (412 men and 647 women, mean age: 60.0 years) who complained of taste disorders were reviewed in our clinic. The patients were asked detailed questions about their history of symptoms, and their emotional status was assessed using a self-rating depression scale. In all subjects, taste functions were measured by electrogustometry (EGM) and filter paper disks (FPD). The grades of their symptoms were assessed with a visual analogue scale (VAS). In addition, the levels of serum iron, copper, and zinc were examined. The patients were treated with zinc sulfate, polaprezinc, iron preparation, herbal medicine, and minor tranquilizers according to the factors causing the taste disorders. The most frequent cause was idiopathic taste disorder (192 cases, 18.2%), the second was psychogenic (186 cases, 17.6%), and the third was drug-induced (179 cases, 16.9%). The recovery rate of the symptoms was 64/92 (70.2%) in post-common cold, 31/35 (88.6%) in iron deficiency, and 85/116 (73.3%) in zinc deficiency. In these groups, the rates of recoveries were better than in the other groups. The recovery period in drug-induced taste disorders was approximately twice as long as the recovery period in the other groups. In the patients who were able to start treatment within 6 months from the onset of taste disorder, the recovery rate was significantly higher and the therapeutic period was significantly shorter than in those who had the disorders for more than 6 months (p<0.05, respectively).
authors.affiliation: Department of Otolaryngology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Sakaguchi
authors.forename: Tomomi
authors.initials: T
authors.lastname: Nin
authors.forename: Hideki
authors.initials: H
authors.lastname: Oka
authors.forename: Emi
authors.initials: E
authors.lastname: Maeda
authors.forename: Atsushi
authors.initials: A
authors.lastname: Negoro
authors.forename: Masanori
authors.initials: M
authors.lastname: Umemoto
authors.forename: Masafumi
authors.initials: M
authors.lastname: Sakagami
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D018450:Disease Progression; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013651:Taste Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology*; D013997:Time Factors; D055815:Young Adult