title: Altruism in terminal cancer patients and rapid tissue donation program: does the theory apply?
abstract: Rapid tissue donation (RTD) is an advancing oncology research procedure for collecting tumors, metastases, and unaffected tissue 2-6 h after death. Researchers can better determine rates of progression, response to treatment, and polymorphic differences among patients. Cancer patients may inquire about posthumous body donation for research to offer a personal contribution to research; however, there are barriers to recruiting for an RTD program. Physicians must reassure the patient that their treatment options and quality of care will not be compromised due to participating in RTD. In this commentary we discuss how theories of altruism may explain cancer patients' desire to participate in an RTD program, the ethical concerns of health care professionals and patients and the use of altruism as a recruitment strategy. We offer recommendations for examining the cultural and ethical climate of the institution prior to initiating such a program such as examining the relationship of healthcare professionals and patients, identifying ethical concerns, and examining ways to promote acceptance and buy-in across professionals, patients, and families.
authors.affiliation: H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, MRC-CANCONT, Tampa, FL, 33612, USA, gwen.quinn@moffitt.org.
authors.forename: Gwendolyn P
authors.initials: GP
authors.lastname: Quinn
authors.forename: Devin
authors.initials: D
authors.lastname: Murphy
authors.forename: Christie
authors.initials: C
authors.lastname: Pratt
authors.forename: Teresita
authors.initials: T
authors.lastname: Muñoz-Antonia
authors.forename: Lucy
authors.initials: L
authors.lastname: Guerra
authors.forename: Matthew B
authors.initials: MB
authors.lastname: Schabath
authors.forename: Marino E
authors.initials: ME
authors.lastname: Leon
authors.forename: Eric
authors.initials: E
authors.lastname: Haura
mesh_terms: D000533:Altruism; D005190:Family / Q000523:psychology; D006801:Humans; D009369:Neoplasms / Q000523:psychology*; D011369:Professional-Patient Relations / Q000941:ethics; D013997:Time Factors; D014019:Tissue Donors / Q000941:ethics* / Q000523:psychology; D009927:Tissue and Organ Procurement / Q000941:ethics / Q000379:methods
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