title: Depression in children and adolescents with epilepsy: a 15 year research review of prevalence, and demographic and seizure related correlates.
abstract: OBJECTIVE
  The paper aims to study the prevalence of depression in epileptic children and adolescents by reviewing the existing literature, looking for any association between depression in these children and their demographic or seizure related factors to highlight the potential risk factors for depression in epileptic children.
  
  
  METHODS
  A search of MEDLINE, NLM Gateway, Ovid and EMBASE was carried out to study original English language articles published during the last 15 years, focusing on only epileptic children and adolescents, studying of depression as comorbidity of epilepsy, and describing demographic and epilepsy-related factors associated with depression.
  
  
  RESULTS
  The 11 articles included in this study have reported data on 1095 epileptic children aged 4-19 years old and showed that the prevalence of depression has continued to be very common in epileptic children and adolescents, ranged from 5.2% to 39.6%. On the whole, the findings did not support the presence of an association between depression and demographic or seizure variables in children.
  
  
  CONCLUSIONS
  Pediatricians and other physicians working with epileptic children should have a high index of suspicion for depression as a comorbid condition in children with epilepsy. Early diagnosis and more comprehensive packages of care for depression in epileptic children will enable them to have a better quality of life.
authors.affiliation: Department of Pediatrics, Semnan University of Medical Sciences, Semnan, Iran.
authors.forename: Seyfhashemi
authors.initials: S
authors.lastname: Maryam
authors.forename: Bahadoran
authors.initials: B
authors.lastname: Parviz
keywords: Adolescents; Children; Depression; Epilepsy; Seizure Variables
references.citation: J Child Neurol. 2002 Jan;17(1):37-40
references.pmid: 11913568
references.citation: Epilepsy Behav. 2005 May;6(3):342-7
references.pmid: 15820341
references.citation: Dev Med Child Neurol. 2007 Jul;49(7):493-7
references.pmid: 17593119
references.citation: Epilepsy Behav. 2003 Oct;4 Suppl 3:S39-45
references.pmid: 14592639
references.citation: J Child Neurol. 2004 Aug;19 Suppl 1:S65-72
references.pmid: 15529462
references.citation: Epilepsia. 1998 Sep;39(9):913-21
references.pmid: 9738670
references.citation: Epilepsia. 1998 Jun;39(6):595-9
references.pmid: 9637601
references.citation: Epilepsia. 2009 Aug;50(8):1943-52
references.pmid: 19260941
references.citation: Seizure. 2000 Sep;9(6):412-6
references.pmid: 10985998
references.citation: Dev Med Child Neurol. 2006 Mar;48(3):213-9
references.pmid: 16483398
references.citation: Epilepsia. 2000 May;41(5):615-23
references.pmid: 10802769
references.citation: Epilepsy Behav. 2004 Dec;5(6):958-64
references.pmid: 15582845
references.citation: Dev Med Child Neurol. 2009 May;51(5):364-72
references.pmid: 19018836
references.citation: Epilepsy Behav. 2004 Dec;5(6):988-94
references.pmid: 15582849
references.citation: Pediatrics. 1987 Dec;80(6):909-17
references.pmid: 3684404
references.citation: Epilepsy Behav. 2008 Jan;12(1):136-44
references.pmid: 17959421
references.citation: Epilepsia. 2005 May;46(5):720-30
references.pmid: 15857439