title: Delusion of pregnancy: a case revisited.
abstract: A patient with delusion of pregnancy as an early feature of frontotemporal dementia with motor neurone disease (FTD/MND) who was reported some years ago was posthumously found to harbor the C9ORF72 hexanucleotide repeat expansion, now known to be the most common genetic cause of FTD/MND. Some series have found psychosis to be common in FTD associated with this mutation, so this test should be considered in individuals with clinical features of FTD and MND and/or with a family history of either disorder who present with bizarre delusions.
authors.affiliation: Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool, L9 7LJ, United Kingdom. Tel.: +44 151 529 5727; Fax: +44 151 529 8552; E-mail: a.larner@thewaltoncentre.nhs.uk.
authors.forename: A J
authors.initials: AJ
authors.lastname: Larner
mesh_terms: D000328:Adult; D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics* / Q000523:psychology; D000073885:C9orf72 Protein; D042622:DNA Repeat Expansion / Q000235:genetics; D003702:Delusions / Q000235:genetics*; D005260:Female; D057180:Frontotemporal Dementia / Q000235:genetics* / Q000523:psychology; D020022:Genetic Predisposition to Disease / Q000235:genetics; D005820:Genetic Testing; D006801:Humans; D011247:Pregnancy; D011506:Proteins / Q000235:genetics*
chemical_list: D000073885:C9orf72 Protein; C568651:C9orf72 protein, human; D011506:Proteins