title: Drug-induced takotsubo cardiomyopathy.
abstract: Takotsubo cardiomyopathy (TTC), also known as stress cardiomyopathy, is an increasingly recognized clinical syndrome of acute reversible left ventricular dysfunction precipitated by intense emotional or physical stress. Excessive sympathetic stimulation is believed to be central to the pathogenesis of this condition; thus, drugs with sympathetic effect could precipitate TTC. This review outlines previous reports regarding drugs that may induce TTC. Some reports link the use of the drug-primarily associated with sympathetic overstimulation-with the development of TTC Consequently, drug-induced TTC should be considered in patients diagnosed with TTC.
authors.affiliation: Department of Pharmacology, Osaka City University Medical School, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585, Japan. izumi@msic.med.osaka-cu.ac.jp
authors.forename: Yasukatsu
authors.initials: Y
authors.lastname: Izumi
mesh_terms: D002395:Catecholamines / Q000009:adverse effects; D006801:Humans; D013566:Sympathomimetics / Q000009:adverse effects; D054549:Takotsubo Cardiomyopathy / Q000139:chemically induced*
chemical_list: D002395:Catecholamines; D013566:Sympathomimetics