title: General morphology and innervation of the midgut and hindgut of Megalobulimus abbreviatus (Gastropoda, Pulmonata).
abstract: We describe the morphology and innervation of the midgut and hindgut of the giant land snail Megalobulimus abbreviatus for the first time. The midgut (stomach and intestine) and hindgut (rectum and anus) are innervated by the subesophageal ganglia, through the gastrointestinal branch (originated from the visceral nerve) and the rectum-anal nerve, respectively. Backfilling through these nerves revealed neuronal bodies, mainly in the right parietal and visceral ganglia. The enteric plexuses of the midgut and hindgut are formed by extensive axonal networks and several neuronal somata arranged in clusters or as isolated cells. The gastrointestinal branch and the rectum-anal nerve directly innervate the enteric plexuses of the intestine and the hindgut, respectively. However, the outer wall of the stomach has a stomatogastric nervous system, which consists of four ganglia: stomatogastric, gastric, cardic, and pyloric. Fibers of the gastrointestinal branch project to these ganglia. Anterograde tracing from stomatogastric system ganglia revealed that the enteric plexus of the stomach is innervated only by these peripheral ganglia. Anterograde tracing of the gastrointestinal branch did not result in labeling in the enteric plexus of the stomach. Therefore, the midgut and hindgut of M. abbreviatus is controlled by an intrinsic innervation, constituted by the submucous and myenteric plexuses, which are innervated directly by neurons from the subesophageal ganglia or indirectly via the stomatogastric nervous system (for the stomach).
authors.affiliation: Neuroscience Graduate Program, Institute of Basic Health Sciences (ICBS), Federal University of Rio Grande do Sul (UFRGS), 90050-170, Porto Alegre, RS, Brazil.
authors.forename: Malcon Andrei
authors.initials: MA
authors.lastname: Martinez-Pereira
authors.forename: Raphaela da Cunha
authors.initials: Rda C
authors.lastname: Franceschi
authors.forename: Graziane de Freitas
authors.initials: Gde F
authors.lastname: Antunes
authors.forename: Bárbara Paranhos
authors.initials: BP
authors.lastname: Coelho
authors.forename: Matilde
authors.initials: M
authors.lastname: Achaval
authors.forename: Denise M
authors.initials: DM
authors.lastname: Zancan
mesh_terms: D000818:Animals; D041981:Gastrointestinal Tract / Q000033:anatomy & histology* / Q000294:innervation*; D049851:Gastropoda / Q000033:anatomy & histology*; D009474:Neurons