title: Intraoperative radiotherapy of early breast cancer using low-kilovoltage x-rays-reasons for omission of planned intraoperative irradiation.
abstract: The purpose of this study is to investigate reasons for omission of a planned intraoperative radiotherapy (IORT) during breast-conserving surgery (BCS). Between 2002 and 2009, in 297 women an IORT during BCS was planned. In 55 women this irradiation was finally not performed. We retrospectively analyzed pre-, peri-, and postoperative data of these 55 women. Main reasons for omission of an IORT were insufficient tumor-skin distance (n = 20, 35.1%), an oversized wound cavity (n = 14, 24.6%), and a combination of both (n = 8, 14%). Further reasons (n = 12, 21.1%) were temporal shortage, unplanned maintenance work of the Intrabeam(®) device, unsuitable anatomicosurgical conditions, and ineligible histologic findings. Apart from suitable anatomic conditions, a precise preoperative ultrasonography as well as a strict interdisciplinary preoperative management is important for successful application of IORT.
authors.affiliation: Department of Gynecology and Obstetrics, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany. benjamin.tuschy@umm.de
authors.forename: Benjamin
authors.initials: B
authors.lastname: Tuschy
authors.forename: Sebastian
authors.initials: S
authors.lastname: Berlit
authors.forename: Christiane
authors.initials: C
authors.lastname: Nasterlack
authors.forename: Karin
authors.initials: K
authors.lastname: Tomé
authors.forename: Elena
authors.initials: E
authors.lastname: Blank
authors.forename: Frederik
authors.initials: F
authors.lastname: Wenz
authors.forename: Marc
authors.initials: M
authors.lastname: Sütterlin
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D012189:Retrospective Studies; D014964:X-Ray Therapy