title: [Collapsing glomerulopathy].
abstract: Collapsing glomerulopathy is a cause of nephrotic syndrome with massive proteinuria secondary to podocyte proliferation and glomerular collapse. It is characterized by an almost inevitable progression to end stage renal failure, poor response to treatment and high post-transplant recurrence. Its frequency has increased in recent years due to its common association with Human Immunodeficiency Virus (HIV) infection and the growing recognition of new etiologic agents such as drugs and parvovirus B19. Therefore, it is a disease of growing interest for clinicians. The aim of this review is to update the clinical presentation, diagnosis, pathogenesis and therapeutic alternatives of this disease.
authors.affiliation: Servicio de Medicina, Hospital San Juan de Dios Santiago, Chile. jcsaid@uc.cl
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Said
authors.forename: Luz María
authors.initials: LM
authors.lastname: Letelier
authors.forename: Alejandro
authors.initials: A
authors.lastname: González
authors.forename: Cristóbal
authors.initials: C
authors.lastname: Escobillana
authors.forename: Raúl
authors.initials: R
authors.lastname: Pisano
mesh_terms: D001706:Biopsy; D005923:Glomerulosclerosis, Focal Segmental / Q000209:etiology / Q000473:pathology / Q000628:therapy; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000473:pathology / Q000628:therapy; D007678:Kidney Glomerulus / Q000473:pathology; D009404:Nephrotic Syndrome / Q000209:etiology / Q000473:pathology / Q000628:therapy