title: Global left ventricular longitudinal strain is associated with decreased melatonin levels in patients with acute myocardial infarction: a two-dimensional speckle tracking study.
abstract: Low circulating melatonin levels predict poor outcome in patients with ST-segment elevation myocardial infarction (STEMI). In the present study, we investigated whether a relationship between myocardial deformation in parameters measured by echocardiography and circulating melatonin level exists. We prospectively included 112 patients with STEMI who performed echocardiography and simultaneous measurement of serum melatonin, during the light period within 72 h of admission. We found a negative correlation between circulating melatonin levels and global longitudinal strain (p = 0.006, r = -0.33). In conclusion, melatonin levels have a correlation with two-dimensional speckle tracking in patients with STEMI.
authors.affiliation: Department of Cardiology, Complejo Hospitalario Universitario de Canarias, Tenerife, Spain. adrvdg@hotmail.com
authors.forename: Alberto
authors.initials: A
authors.lastname: Dominguez-Rodriguez
authors.forename: Pedro
authors.initials: P
authors.lastname: Abreu-Gonzalez
authors.forename: Eduardo
authors.initials: E
authors.lastname: Arroyo-Ucar
authors.forename: Pablo
authors.initials: P
authors.lastname: Avanzas
authors.forename: Russel J
authors.initials: RJ
authors.lastname: Reiter
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood*; D005260:Female; D006352:Heart Ventricles / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008550:Melatonin / Q000097:blood*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000503:physiopathology*; D011446:Prospective Studies
chemical_list: D015415:Biomarkers; D008550:Melatonin