title: C7 nerve root sensory distribution in peripheral nerves: a bold functional magnetic resonance imaging investigation at 9.4 T.
abstract: BACKGROUND
  In this study we used a rat model to elucidate the linear make-up of each major nerve of the upper limb by the C7 root through sensory stimulation and functional magnetic resonance imaging (fMRI).
  
  
  METHODS
  The C7 nerve root and major nerves of the right forelimb were stimulated electrically. Blood oxygen level-dependent functional magnetic resonance imaging (BOLD fMRI) was performed concurrently. Voxel overlap within the primary sensory cortex was calculated.
  
  
  RESULTS
  C7 comprised sensation in <1% in the musculocutaneous nerve, 6% in the ulnar nerve, 16% in the radial nerve, and 19% in the median nerve (P<0.005 for each). The overlap was always <25% for each major nerve.
  
  
  CONCLUSIONS
  This study helps explain why C7 is a suitable donor for brachial plexus injury treatment and why there is only a transient sensory deficit after transfer.
authors.forename: Rupeng
authors.initials: R
authors.lastname: Li
authors.forename: Jacques A
authors.initials: JA
authors.lastname: Machol
authors.forename: Xiping
authors.initials: X
authors.lastname: Liu
authors.forename: Patrick C
authors.initials: PC
authors.lastname: Hettinger
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Flugstad
authors.forename: Ji-geng
authors.initials: JG
authors.lastname: Yan
authors.forename: Hani S
authors.initials: HS
authors.lastname: Matloub
authors.forename: James S
authors.initials: JS
authors.lastname: Hyde
mesh_terms: D000818:Animals; D004558:Electric Stimulation; D005154:Facial Nerve / Q000033:anatomy & histology* / Q000502:physiology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008475:Median Nerve / Q000033:anatomy & histology / Q000502:physiology; D023421:Models, Animal; D010525:Peripheral Nerves / Q000033:anatomy & histology* / Q000502:physiology; D011826:Radial Nerve / Q000033:anatomy & histology / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013003:Somatosensory Cortex / Q000033:anatomy & histology / Q000502:physiology; D013126:Spinal Nerve Roots / Q000033:anatomy & histology* / Q000502:physiology; D014459:Ulnar Nerve / Q000033:anatomy & histology / Q000502:physiology
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