title: Study of living kidney donor-recipient relationships: variation with socioeconomic deprivation in the white population of England.
abstract: BACKGROUND
  Socioeconomic deprivation is associated with higher renal replacement therapy acceptance rates in the UK but lower rates of living kidney transplantation. This study examines donor-recipient relationship patterns with socioeconomic deprivation in the white population of England.
  
  
  METHODS
  Demographic characteristics of all white live renal transplant donors and recipients between 2001 and 2010 in England were analyzed. Patterns of donor-recipient relationship were analyzed to see whether they differed according to an ecological measure of socioeconomic status (Index of Multiple Deprivation). Group comparisons were performed using chi-square tests and multivariable logistic regression.
  
  
  RESULTS
  Sources of living kidney transplants differed with deprivation (p < 0.001). Recipients living in poorer areas were more likely to receive a kidney from a sibling, child, and "other relative" donor and less likely from spouses/partners. Logistic regression suggested differences seen with spouse/partner donations with deprivation were explained by differences in the age and gender of the recipients.
  
  
  CONCLUSIONS
  The source of living kidneys differs by level of area deprivation. Given the disparity in rates of living kidney transplants between the most and least socioeconomically deprived, there is a need to understand the reasons behind these observed relationship differences, with the aim of increasing transplantation rates in the most deprived.
authors.affiliation: The Richard Bright Renal Unit, Southmead Hospital, Bristol, UK. pippabailey@hotmail.com
authors.forename: Phillippa K
authors.initials: PK
authors.lastname: Bailey
authors.forename: Charles Rv
authors.initials: CR
authors.lastname: Tomson
authors.forename: Yoav
authors.initials: Y
authors.lastname: Ben-Shlomo
mesh_terms: D000328:Adult; D002648:Child; D005190:Family; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007398:Interpersonal Relations; D016030:Kidney Transplantation / Q000009:adverse effects*; D019520:Living Donors / Q000523:psychology* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011204:Poverty Areas; D011379:Prognosis; D012959:Socioeconomic Factors; D018454:Spouses; D009927:Tissue and Organ Procurement; D044465:White People / Q000706:statistics & numerical data*