title: Childhood leukaemia close to high-voltage power lines--the Geocap study, 2002-2007.
abstract: BACKGROUND
  High-voltage overhead power lines (HVOLs) are a source of extremely low-frequency magnetic fields (ELF-MFs), which are classified as possible risk factors for childhood acute leukaemia (AL). The study was carried out to test the hypothesis of an increased AL incidence in children living close to HVOL of 225-400 kV (VHV-HVOL) and 63-150 kV (HV-HVOL).
  
  
  METHODS
  The nationwide Geocap study included all the 2779 cases of childhood AL diagnosed in France over 2002-2007 and 30 000 contemporaneous population controls. The addresses at the time of inclusion were geocoded and precisely located around the whole HVOL network.
  
  
  RESULTS
  Increased odds ratios (ORs) were observed for AL occurrence and living within 50 m of a VHV-HVOL (OR=1.7 (0.9-3.6)). In contrast, there was no association with living beyond that distance from a VHV-HVOL or within 50 m of a HV-HVOL.
  
  
  CONCLUSIONS
  The present study, free from any participation bias, supports the previous international findings of an increase in AL incidence close to VHV-HVOL. In order to investigate for a potential role of ELF-MF in the results, ELF-MF at the residences close to HVOL are to be estimated, using models based on the annual current loads and local characteristics of the lines.
authors.affiliation: Inserm, Center for Research in Epidemiology and Population Health (CESP), U1018, Environmental Epidemiology of Cancer Team, Villejuif F-94807, France.
authors.forename: C
authors.initials: C
authors.lastname: Sermage-Faure
authors.forename: C
authors.initials: C
authors.lastname: Demoury
authors.forename: J
authors.initials: J
authors.lastname: Rudant
authors.forename: S
authors.initials: S
authors.lastname: Goujon-Bellec
authors.forename: A
authors.initials: A
authors.lastname: Guyot-Goubin
authors.forename: F
authors.initials: F
authors.lastname: Deschamps
authors.forename: D
authors.initials: D
authors.lastname: Hemon
authors.forename: J
authors.initials: J
authors.lastname: Clavel
mesh_terms: D000293:Adolescent; D002648:Child; D011211:Electric Power Supplies / Q000009:adverse effects; D004560:Electricity / Q000009:adverse effects*; D004574:Electromagnetic Fields / Q000009:adverse effects*; D004781:Environmental Exposure / Q000009:adverse effects*; D005260:Female; D005602:France / Q000453:epidemiology; D062305:Geographic Mapping; D006801:Humans; D007938:Leukemia / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D016017:Odds Ratio; D012111:Residence Characteristics; D012307:Risk Factors
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