title: The geometry of locomotive behavioral states in C. elegans.
abstract: We develop a new hidden Markov model-based method to analyze C elegans locomotive behavior and use this method to quantitatively characterize behavioral states. In agreement with previous work, we find states corresponding to roaming, dwelling, and quiescence. However, we also find evidence for a continuum of intermediate states. We suggest that roaming, dwelling, and quiescence may best be thought of as extremes which, mixed in any proportion, define the locomotive repertoire of C elegans foraging and feeding behavior.
authors.affiliation: Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, Virginia, United States of America.
authors.forename: Thomas
authors.initials: T
authors.lastname: Gallagher
authors.forename: Theresa
authors.initials: T
authors.lastname: Bjorness
authors.forename: Robert
authors.initials: R
authors.lastname: Greene
authors.forename: Young-Jai
authors.initials: YJ
authors.lastname: You
authors.forename: Leon
authors.initials: L
authors.lastname: Avery
mesh_terms: D000465:Algorithms; D000818:Animals; D001398:Aztreonam / Q000494:pharmacology; D001522:Behavior, Animal; D017173:Caenorhabditis elegans / Q000502:physiology*; D005247:Feeding Behavior; D005838:Genotype; D008124:Locomotion; D008390:Markov Chains; D008954:Models, Biological; D025341:Principal Component Analysis; D011336:Probability
chemical_list: D001398:Aztreonam
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