title: Acceptability of oral iodinated contrast media: a head-to-head comparison of four media.
abstract: OBJECTIVE
  To assess the palatability of iodinated oral contrast media commonly used in abdominopelvic CT and CT colonography (CTC).
  
  
  METHODS
  80 volunteers assessed the palatability of a 20-ml sample of a standard 30 mg ml(-1) dilution of Omnipaque® (iohexol; GE Healthcare, Cork, Ireland), Telebrix® (meglumine ioxithalamate; Guerbet, Aulnay-sous-Bois, France), Gastromiro® (iopamidol; Bracco, High Wycombe, UK) and Gastrografin® (sodium diatrizoate and meglumine diatrizoate; Bayer, Newbury, UK) in a computer-generated random order.
  
  
  RESULTS
  Gastrografin is rated significantly less palatable than the remaining media (p<0.005). Omnipaque and Telebrix are significantly more palatable than Gastromiro. No difference existed between Omnipaque and Telebrix. 39% of participants would refuse to consume the quantities of Gastrografin required for a CTC examination compared with Telebrix (7%) and Omnipaque (9%) (p<0.05).
  
  
  CONCLUSIONS
  Omnipaque and Telebrix are significantly more palatable than both Gastromiro and Gastrografin, with participants more willing to ingest them in larger quantities as well as being less expensive.
  
  
  CONCLUSIONS
  Omnipaque and Telebrix are significantly more palatable iodinated oral contrast media than both Gastromiro and Gastrografin, which has potential implications in compliance with both abdominopelvic CT and CTC.
authors.affiliation: Department of Radiology, Southmead Hospital, Bristol, UK. adrianpollentine@doctors.org.uk
authors.forename: A
authors.initials: A
authors.lastname: Pollentine
authors.forename: E
authors.initials: E
authors.lastname: Ngan-Soo
authors.forename: P
authors.initials: P
authors.lastname: McCoubrie
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D003287:Contrast Media / Q000008:administration & dosage*; D003973:Diatrizoate / Q000008:administration & dosage*; D003974:Diatrizoate Meglumine / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007472:Iohexol / Q000008:administration & dosage; D007479:Iopamidol / Q000008:administration & dosage; D007482:Iothalamate Meglumine / Q000008:administration & dosage*; D008297:Male; D017060:Patient Satisfaction / Q000706:statistics & numerical data*; D013649:Taste; D014283:Triiodobenzoic Acids / Q000008:administration & dosage*; D055815:Young Adult
chemical_list: D003287:Contrast Media; D014283:Triiodobenzoic Acids; D003973:Diatrizoate; D003974:Diatrizoate Meglumine; D007472:Iohexol; C001694:meglumine ioxithalamate; D007479:Iopamidol; D007482:Iothalamate Meglumine
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