title: Pyrazolines: a biological review.
abstract: Pyrazoline is an important five membered nitrogen heterocycle, which has been extensively researched upon. The ring is quite stable and has inspired chemists to carry out various structural variations in the ring. This has propelled the development of distinct pyrazolines with an array of pharmacological activities viz. anti-inflammatory, analgesic, antimicrobial, anticancer, antidepressant etc. The review aims at highlighting this pharmacological diversity of pyrazolines. The review is a gist of latest work done describing the pharmacological aspects and potential of pyrazoline ring.
authors.affiliation: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard. New Delhi -110062, India.
authors.forename: Akranth
authors.initials: A
authors.lastname: Marella
authors.forename: Md Rahmat
authors.initials: MR
authors.lastname: Ali
authors.forename: Md Tauquir
authors.initials: MT
authors.lastname: Alam
authors.forename: Rikta
authors.initials: R
authors.lastname: Saha
authors.forename: Omprakash
authors.initials: O
authors.lastname: Tanwar
authors.forename: Mymoona
authors.initials: M
authors.lastname: Akhter
authors.forename: Md
authors.initials: M
authors.lastname: Shaquiquzzaman
authors.forename: M Mumtaz
authors.initials: MM
authors.lastname: Alam
mesh_terms: D000700:Analgesics / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D000981:Antiprotozoal Agents / Q000737:chemistry / Q000494:pharmacology; D002317:Cardiovascular Agents / Q000737:chemistry / Q000494:pharmacology; D002490:Central Nervous System / Q000187:drug effects; D006801:Humans; D007004:Hypoglycemic Agents / Q000737:chemistry / Q000494:pharmacology; D008996:Monoamine Oxidase Inhibitors / Q000737:chemistry / Q000494:pharmacology; D011720:Pyrazoles / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000700:Analgesics; D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000970:Antineoplastic Agents; D000975:Antioxidants; D000981:Antiprotozoal Agents; D002317:Cardiovascular Agents; D007004:Hypoglycemic Agents; D008996:Monoamine Oxidase Inhibitors; D011720:Pyrazoles