title: Green synthesis of silver nanoparticles from leaf extract of Mimusops elengi, Linn. for enhanced antibacterial activity against multi drug resistant clinical isolates.
abstract: Green synthesis of metallic silver nanoparticles has attracted nowadays and alternative to physical and chemical approaches. In the present study, silver nanoparticles (AgNPs) were synthesized from leaf extract of Mimusops elengi, L. at room temperature. Formation of stable AgNPs at 1mM concentrations of silver nitrate (AgNO3) typically gave spherical shape particles with diameter range from 55 to 83nm. The kinetic properties of particle formation were proportional to the effect of concentration of AgNO3 solution. In order to identify the compounds responsible for the bioreduction of Ag(+) ion and the stabilization of AgNPs produced, the functional group present in Mimusops elengi, L. leaf extract was investigated using FTIR. The formation of nanoparticle was confirmed using the surface plasmon resonance band shown in UV-vis spectrophotometer. The topography and morphology of the particles were determined using scanning electron microscopy. The crystalline nature of nanoparticles was confirmed from the XRD pattern. Furthermore these green synthesized AgNPs were found to show higher antimicrobial efficacy against multi drug resistant clinical isolates.
authors.affiliation: Department of Chemistry, Thiagarajar College, Madurai, Tamil Nadu 625009, India.
authors.forename: P
authors.initials: P
authors.lastname: Prakash
authors.forename: P
authors.initials: P
authors.lastname: Gnanaprakasam
authors.forename: R
authors.initials: R
authors.lastname: Emmanuel
authors.forename: S
authors.initials: S
authors.lastname: Arokiyaraj
authors.forename: M
authors.initials: M
authors.lastname: Saravanan
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D024901:Drug Resistance, Multiple, Bacterial; D055772:Green Chemistry Technology; D006801:Humans; D007700:Kinetics; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000254:growth & development / Q000302:isolation & purification; D053768:Metal Nanoparticles / Q000737:chemistry*; D016982:Micrococcus luteus / Q000187:drug effects / Q000254:growth & development / Q000302:isolation & purification; D032130:Mimusops / Q000737:chemistry*; D010084:Oxidation-Reduction; D010316:Particle Size; D010936:Plant Extracts / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development / Q000302:isolation & purification; D020349:Surface Plasmon Resonance; D013696:Temperature
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D012834:Silver