title: Characterization of the ultrasound beam produced by the MIST therapy, wound healing system.
abstract: The MIST Therapy wound healing device (Celleration, Eden Prairie, MN, USA), which uses low-frequency ultrasound to deliver an atomized saline spray to acute wounds, was evaluated in a laboratory environment. The output of the MIST device was characterized by its frequency, transmission in the presence and absence of the saline spray and intensity. When measured up to 500 mm away from the transducer tip, the transmission of 39.5 kHz ultrasound was not significantly attenuated by the saline itself. In the absence of the saline spray, the acoustic intensity range of the MIST device was calculated to be 429-188 mW cm(-2) across the manufacturer-specified treatment range (12.5-20 mm). Because of the acoustic impedance mismatch between air and soft tissue, the MIST Therapy device would deliver only 0.1% of this incident intensity into the wound site.
authors.affiliation: Department of Medical Physics, Freeman Hospital, Newcastle Upon Tyne, UK.
authors.forename: K
authors.initials: K
authors.lastname: Keltie
authors.forename: C A
authors.initials: CA
authors.lastname: Reay
authors.forename: D R
authors.initials: DR
authors.lastname: Bousfield
authors.forename: H
authors.initials: H
authors.lastname: Cole
authors.forename: B
authors.initials: B
authors.lastname: Ward
authors.forename: C P
authors.initials: CP
authors.lastname: Oates
authors.forename: A J
authors.initials: AJ
authors.lastname: Sims
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D019220:High-Energy Shock Waves; D006801:Humans; D011874:Radiometry / Q000379:methods*; D012542:Scattering, Radiation; D014464:Ultrasonic Therapy / Q000295:instrumentation* / Q000379:methods*; D014945:Wound Healing / Q000528:radiation effects*