title: Ring around the Ro-sie: RNA-mediated alterations of PNPase activity.
abstract: Chen et al. demonstrate a new way by which noncoding RNAs tailor the function of multicomponent complexes. They show that a noncoding RNA interacts with an exoribonuclease, altering its substrate specificity and enzymatic activity by serving as a ribonucleoprotein scaffold and, perhaps, a gate for entry of the RNA substrate.
authors.affiliation: Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA. brian.geiss@colostate.edu
authors.forename: Brian J
authors.initials: BJ
authors.lastname: Geiss
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Wilusz
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