title: Long-term observation of the mineral trioxide aggregate extrusion into the periapical lesion: a case series.
abstract: One-step apexification using mineral trioxide aggregate (MTA) has been reported as an alternative treatment modality with more benefits than the use of long-term calcium hydroxide for teeth with open apex. However, orthograde placement of MTA is a challenging procedure in terms of length control. This case series describes the sequence of events following apical extrusion of MTA into the periapical area during a one-step apexification procedure for maxillary central incisor with an infected immature apex. Detailed long-term observation revealed complete resolution of the periapical radiolucent lesion around the extruded MTA. These cases revealed that direct contact with MTA had no negative effects on healing of the periapical tissues. However, intentional MTA overfilling into the periapical lesion is not to be recommended.
authors.affiliation: Department of Conservative Dentistry, School of Dentistry, Kyung Hee University, Seoul, Korea.
authors.forename: Seok-Woo
authors.initials: SW
authors.lastname: Chang
authors.forename: Tae-Seok
authors.initials: TS
authors.lastname: Oh
authors.forename: WooCheol
authors.initials: W
authors.lastname: Lee
authors.forename: Gary Shun-Pan
authors.initials: GS
authors.lastname: Cheung
authors.forename: Hyeon-Cheol
authors.initials: HC
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D017607:Aluminum Compounds / Q000009:adverse effects*; D056624:Apexification / Q000379:methods*; D017610:Calcium Compounds / Q000009:adverse effects*; D003751:Dental Fistula / Q000628:therapy; D003790:Dental Pulp Necrosis / Q000628:therapy; D004338:Drug Combinations; D005260:Female; D005500:Follow-Up Studies; D005547:Foreign Bodies / Q000209:etiology*; D006171:Gutta-Percha / Q000627:therapeutic use; D006801:Humans; D007180:Incisor / Q000473:pathology; D008137:Longitudinal Studies; D008297:Male; D010087:Oxides / Q000009:adverse effects*; D010482:Periapical Abscess / Q000628:therapy*; D012387:Root Canal Filling Materials / Q000009:adverse effects*; D012389:Root Canal Obturation / Q000009:adverse effects; D018915:Root Canal Preparation / Q000379:methods; D017640:Silicates / Q000009:adverse effects*; D019227:Tooth Apex / Q000473:pathology; D016896:Treatment Outcome; D014945:Wound Healing / Q000502:physiology
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D004338:Drug Combinations; D010087:Oxides; D012387:Root Canal Filling Materials; D017640:Silicates; C086631:mineral trioxide aggregate; D006171:Gutta-Percha
references.citation: Aust Endod J. 2003 Apr;29(1):34-42
references.pmid: 12772971
references.citation: Pract Proced Aesthet Dent. 2001 Aug;13(6):455-60; quiz 462
references.pmid: 11544818
references.citation: Conf Proc IEEE Eng Med Biol Soc. 2006;2006:2094-7
references.pmid: 17946495
references.citation: J Endod. 2002 May;28(5):386-90
references.pmid: 12033201
references.citation: J Endod. 2009 May;35(5):745-9
references.pmid: 19410097
references.citation: J Am Dent Assoc. 2006 May;137(5):610-8
references.pmid: 16739540
references.citation: J Endod. 2006 Dec;32(12):1205-13
references.pmid: 17174685
references.citation: Int Endod J. 2006 Jan;39(1):2-9
references.pmid: 16409322
references.citation: Dent Traumatol. 2002 Aug;18(4):217-21
references.pmid: 12442832
references.citation: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Jun;105(6):e61-5
references.pmid: 18417384
references.citation: J Endod. 1999 Mar;25(3):197-205
references.pmid: 10321187
references.citation: J Endod. 2004 Feb;30(2):120-2
references.pmid: 14977312
references.citation: J Endod. 1987 Jan;13(1):1-5
references.pmid: 3469295
references.citation: J Endod. 1998 Jul;24(7):468-71
references.pmid: 9693572
references.citation: Dent Traumatol. 2005 Feb;21(1):1-8
references.pmid: 15660748
references.citation: J Oral Rehabil. 2005 Feb;32(2):145-50
references.pmid: 15641982
references.citation: Int Endod J. 2007 Jun;40(6):478-84
references.pmid: 17403040
references.citation: Int Endod J. 2007 Mar;40(3):186-97
references.pmid: 17305695
references.citation: Dent Traumatol. 2003 Jun;19(3):165-9
references.pmid: 12752539
references.citation: Dent Traumatol. 2002 Jun;18(3):134-7
references.pmid: 12110105
references.citation: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Mar;103(3):e92-9
references.pmid: 17208469
references.citation: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Oct;104(4):e98-101
references.pmid: 17625928
references.citation: J Endod. 2008 Jul;34(7):812-7
references.pmid: 18570985
references.citation: J Endod. 2004 Dec;30(12):876-9
references.pmid: 15564868
references.citation: Aust Endod J. 2003 Apr;29(1):43-4
references.pmid: 12772972
references.citation: J Endod. 2008 Jul;34(7):876-87
references.pmid: 18571000
references.citation: J Endod. 2006 May;32(5):456-9
references.pmid: 16631848
references.citation: Dent Clin North Am. 1992 Apr;36(2):439-57
references.pmid: 1349289
references.citation: J Endod. 1999 Jan;25(1):1-5
references.pmid: 10196834
references.citation: J Endod. 1979 Oct;5(10):290-7
references.pmid: 297749
references.citation: J Endod. 2009 Jun;35(6):777-90
references.pmid: 19482173
references.citation: J Endod. 2007 Jun;33(6):693-7
references.pmid: 17509408