title: New applications of nanotechnology for neuroimaging.
abstract: Advances in nanotechnology have the potential to dramatically enhance the detection of neurologic diseases with targeted contrast agents and to facilitate the delivery of focused therapies to the central nervous system. We present the physicochemical rationale for their use, applications in animal models, and ongoing clinical trials using these approaches. We highlight advances in the use of nanoparticles applied to brain tumor imaging, tumor angiogenesis, neurodegeneration, grafted stem cells, and neuroprogenitor cells.
authors.affiliation: From the George Washington University School of Medicine and Health Sciences (G.S.), Washington, DC.
authors.forename: G
authors.initials: G
authors.lastname: Suffredini
authors.affiliation: Howard University School of Medicine (J.E.E.), Washington, DC.
authors.forename: J E
authors.initials: JE
authors.lastname: East
authors.affiliation: Department of Radiology (L.M.L.), George Washington University Medical Center, Washington, DC. llevy@mfa.gwu.edu.
authors.forename: L M
authors.initials: LM
authors.lastname: Levy
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism* / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis*; D003287:Contrast Media; D006801:Humans; D057054:Molecular Imaging / Q000639:trends*; D053758:Nanoparticles; D036103:Nanotechnology / Q000639:trends*; D059906:Neuroimaging / Q000639:trends*
chemical_list: D003287:Contrast Media
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