title: Evidence-based management of PAD & the diabetic foot.
abstract: Diabetic foot ulceration (DFU) is associated with high morbidity and mortality, and represents the leading cause of hospitalization in patients with diabetes. Peripheral arterial disease (PAD), present in half of patients with DFU, is an independent predictor of limb loss and can be difficult to diagnose in a diabetic population. This review focuses on the evidence for therapeutic strategies in the management of patients with DFU. We highlight the importance of timely referral of patients presenting with a new foot ulcer to a multidisciplinary team, which includes vascular surgeons and interventional radiologists.
authors.affiliation: St George's Vascular Institute, St George's Healthcare NHS Trust, London, UK. j.brownrigg@doctors.org.uk
authors.forename: J R W
authors.initials: JR
authors.lastname: Brownrigg
authors.forename: J
authors.initials: J
authors.lastname: Apelqvist
authors.forename: K
authors.initials: K
authors.lastname: Bakker
authors.forename: N C
authors.initials: NC
authors.lastname: Schaper
authors.forename: R J
authors.initials: RJ
authors.lastname: Hinchliffe
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002317:Cardiovascular Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D017719:Diabetic Foot / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D057510:Endovascular Procedures; D019317:Evidence-Based Medicine; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D010348:Patient Care Team; D058729:Peripheral Arterial Disease / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D012017:Referral and Consultation; D012307:Risk Factors; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures
chemical_list: D000900:Anti-Bacterial Agents; D002317:Cardiovascular Agents; D007004:Hypoglycemic Agents