title: Metal-free, highly efficient organocatalytic amination of benzylic C-H bonds.
abstract: A new synthetic approach toward direct C-N bond formation through sp(3) C-H activation has been developed under metal-free conditions. Both primary and secondary benzylic C-H substrates could react smoothly with various amines to give only mono-amination products with good to excellent yields.
authors.affiliation: State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, People's Republic of China.
authors.forename: Qicai
authors.initials: Q
authors.lastname: Xue
authors.forename: Jin
authors.initials: J
authors.lastname: Xie
authors.forename: Huamin
authors.initials: H
authors.lastname: Li
authors.forename: Yixiang
authors.initials: Y
authors.lastname: Cheng
authors.forename: Chengjian
authors.initials: C
authors.lastname: Zhu
mesh_terms: D000586:Amination; D000588:Amines / Q000737:chemistry*; D001555:Benzene Derivatives / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D006859:Hydrogen / Q000737:chemistry; D009584:Nitrogen / Q000737:chemistry; D016877:Oxidants / Q000737:chemistry*; D020122:tert-Butylhydroperoxide / Q000737:chemistry*
chemical_list: D000588:Amines; D001555:Benzene Derivatives; D016877:Oxidants; D002244:Carbon; D006859:Hydrogen; D020122:tert-Butylhydroperoxide; D009584:Nitrogen