title: Cellular internalization of quantum dots.
abstract: Cell-penetrating peptides (CPPs) can facilitate uptake of quantum dots (QDs) for a variety of basic and applied sciences. Here we describe a method that utilizes simple noncovalent interactions to complex QDs and CPPs. We further describe methods to study uptake mechanisms of the QD/CPP complex. The inhibitor study coupled with the RNA interference (RNAi) technique provides a comprehensive approach to elucidate cellular entry of the QD/CPP complex.
authors.affiliation: Department of Biological Sciences, Missouri University of Science and Technology, Rolla, MO, USA.
authors.forename: Yue-Wern
authors.initials: YW
authors.lastname: Huang
authors.forename: Han-Jung
authors.initials: HJ
authors.lastname: Lee
authors.forename: Betty Revon
authors.initials: BR
authors.lastname: Liu
authors.forename: Huey-Jenn
authors.initials: HJ
authors.lastname: Chiang
authors.forename: Chi-Heng
authors.initials: CH
authors.lastname: Wu
mesh_terms: D001483:Base Sequence; D010873:Pinocytosis; D045663:Quantum Dots; D034622:RNA Interference; D034741:RNA, Small Interfering
chemical_list: D034741:RNA, Small Interfering