title: Physics and engineering aspects of cell and tissue imaging systems: microscopic devices and computer assisted diagnosis.
abstract: The conventional optical microscopes have been used widely in scientific research and in clinical practice. The modern digital microscopic devices combine the power of optical imaging and computerized analysis, archiving and communication techniques. It has a great potential in pathological examinations for improving the efficiency and accuracy of clinical diagnosis. This chapter reviews the basic optical principles of conventional microscopes, fluorescence microscopes and electron microscopes. The recent developments and future clinical applications of advanced digital microscopic imaging methods and computer assisted diagnosis schemes are also discussed.
authors.affiliation: College of Precision Instruments, Tianjin University, Tianjin, China.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Chen
authors.forename: Liqiang
authors.initials: L
authors.lastname: Ren
authors.forename: Bin
authors.initials: B
authors.lastname: Zheng
authors.forename: Hong
authors.initials: H
authors.lastname: Liu
mesh_terms: D000818:Animals; D058948:Cell Tracking / Q000295:instrumentation*; D003581:Cytodiagnosis / Q000295:instrumentation*; D004867:Equipment Design; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000295:instrumentation* / Q000379:methods; D008853:Microscopy / Q000295:instrumentation*; D057054:Molecular Imaging / Q000295:instrumentation*