title: Thyroid dysfunction in type 2 diabetes mellitus: A retrospective study.
abstract: BACKGROUND
  Type 2 diabetes mellitus (DM) is a growing problem in our country and we have observed that many patients are associated with thyroid dysfunction later in their life. However, the prevalence of thyroid dysfunction in these patients has not been investigated.
  
  
  OBJECTIVE
  To find the prevalence of thyroid dysfunction in type 2 DM in Manipur, India.
  
  
  METHODS
  In this retrospective study, data of 202 Type 2 DM patients who attended the diabetic clinic of the Regional Institute of Medical Sciences, Imphal from January 2011 to July 2012, and whose thyroid stimulating hormone (TSH) level was investigated were included. The inclusion criteria are known cases of type 2 DM. Exclusion criteria are patients with previous history of hypothyroidism and those on drugs affecting the thyroid profile.
  
  
  RESULTS
  Out the 202 type 2 DM patients for the study of which 61 are males and 141 are females, 139 (68.8%) are euthyroid, 33 (16.3%) have subclinical hypothyroidism (10 males and 23 females), 23 (11.4%) have hypothyroidism (6 males and 17 females), 4 (2%) have subclinical hyperthyroidism and 3 (1.5%) are hyperthyroidism cases. Maximum cases were of hypothyroidism (subclinical and clinical) seen in the age group of 45-64 years. Patients with BMI > 25 were at increased risk of having hypothyroidism (P < 0.016).
  
  
  CONCLUSIONS
  Prevalence of hypothyroidism is quite high in type 2 DM patients above 45 years and more so if their BMI is over 25.
authors.affiliation: Department of Medicine, Regional Institute of Medical Sciences, Imphal, Manipur, India.
authors.forename: Laloo
authors.initials: L
authors.lastname: Demitrost
authors.forename: Salam
authors.initials: S
authors.lastname: Ranabir
keywords: TSH; thyroid dysfunction; type 2 DM
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