title: Neurally adjusted ventilatory assist in non-invasive ventilation.
abstract: This manuscript describes the motivation for developing neurally adjusted ventilatory assist (NAVA) and its subsequent use with a non-invasive interface. The challenges with conventional, pneumatically controlled non-invasive modes are briefly described, followed by a mini-review on the upper airways and the diaphragm electrical activity (EAdi) signal. The bulk of the review focuses on the importance and use of monitoring the EAdi during non-invasive ventilation, and a report of the recent experimental and clinical findings with NAVA during non-invasive ventilation. In summary, non-invasive NAVA provides a truly synchronized mode of non-invasive ventilation, both in time and in level of assist. Along with EAdi monitoring, NAVA can increase the confidence to treat respiratory failure non-invasively.
authors.affiliation: Department of Critical Care, Keenan Research Centre in the Li Ka Shing Knowledge Institute of St. Michael's Hospital. sinderbyc@smh.ca
authors.forename: C
authors.initials: C
authors.lastname: Sinderby
authors.forename: J
authors.initials: J
authors.lastname: Beck
mesh_terms: D003964:Diaphragm / Q000503:physiopathology; D006801:Humans; D008991:Monitoring, Physiologic; D009043:Motor Activity / Q000502:physiology; D009424:Nervous System Physiological Phenomena; D063087:Noninvasive Ventilation / Q000295:instrumentation* / Q000379:methods; D015656:Respiratory Mechanics / Q000502:physiology