title: Perioperative chemotherapy: when to use it, what to use, and why.
abstract: This article provides an overview of intravesical chemotherapy agents used for non-muscle invasive bladder cancer; summarizes the evidence on single-dose perioperative administration, induction therapy, and maintenance therapy; and briefly discusses ongoing research.
authors.affiliation: Department of Urology, University of North Carolina, Chapel Hill, NC 27599-7235, USA.
authors.forename: David C
authors.initials: DC
authors.lastname: Johnson
authors.forename: Raj S
authors.initials: RS
authors.lastname: Pruthi
authors.forename: Michael E
authors.initials: ME
authors.lastname: Woods
mesh_terms: D000283:Administration, Intravesical; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects; D003131:Combined Modality Therapy; D003841:Deoxycytidine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy* / Q000601:surgery; D000093542:Gemcitabine
chemical_list: D000964:Antimetabolites, Antineoplastic; D000970:Antineoplastic Agents; D003841:Deoxycytidine; D000093542:Gemcitabine