title: Effect of calcium hydroxide premedication on the marginal adaptation of calcium-enriched mixture cement apical plug.
abstract: BACKGROUND
  This study was to evaluate the effects of calcium hydroxide premedication on the marginal adaptation of the calcium-enriched mixture (CEM) cement as an apical plug.
  
  
  METHODS
  In this in vitro study, forty single rooted teeth were prepared and apical portion of the roots were immersed in sulfuric acid to produce open apices. The teeth were divided into 2 experimental groups. In medicated group, calcium hydroxide was placed in all canals for 1 week and in non-medicated group no dressing was used. Then, a 4-mm apical plug of CEM cement was placed in canals; each root was prepared for observation using scanning electron microscope and the maximum distance between CEM cement and surrounding dentin was measured. The data were analyzed by t-test, and significance level was set at α = 0.05.
  
  
  RESULTS
  The mean width of gap in medicated and non-medicated groups was 158/1 μm and 147/1 μm, respectively. There was no significant difference between the two groups (P > 0.05).
  
  
  CONCLUSIONS
  Calcium hydroxide premedication had no adverse effect on the marginal adaptation of CEM cement apical plug.
authors.affiliation: Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Bidar
authors.forename: Reza
authors.initials: R
authors.lastname: Disfani
authors.forename: Saeed
authors.initials: S
authors.lastname: Asgary
authors.forename: Maryam
authors.initials: M
authors.lastname: Forghani
authors.forename: Salman
authors.initials: S
authors.lastname: Gharagozlo
authors.forename: Armita
authors.initials: A
authors.lastname: Rouhani
keywords: Apical plug; calcium hydroxide; calcium-enriched mixture cement; marginal adaptation; scanning electron microscopy
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