title: Development of pyloric stenosis after a 4-day course of oral erythromycin.
abstract: Early exposure to oral erythromycin in young infants, particularly in the first 2 weeks of life, has previously been associated with the development of hypertrophic pyloric stenosis. We report a case of an infant who received an abbreviated 4-day course of oral erythromycin for suspected Chlamydia conjunctivitis at 5 days of life then underwent pyloromyotomy for pyloric stenosis less than 2 weeks later. Health care providers should use erythromycin judiciously in neonates because only a few days of exposure to this medication may lead to the development of a surgical condition of gastric outlet obstruction.
authors.affiliation: Department of Pediatrics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
authors.forename: Luis E
authors.initials: LE
authors.lastname: Lozada
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Royall
authors.forename: Cade M
authors.initials: CM
authors.lastname: Nylund
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Eberly
mesh_terms: D000284:Administration, Oral; D004917:Erythromycin / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D046248:Pyloric Stenosis, Hypertrophic / Q000139:chemically induced* / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D004917:Erythromycin