title: [New data for the pathomechanism of neuropathic pain: therapeutic evidences].
abstract: The present work is based on literature data from PubMed. Neuropathic pain is caused by a lesion or disease of the somatosensory system. Peripheral and central sensitization play a crucial role in its pathomechanism. The clinical symptoms are mainly characterized by burning and throbbing pain and sensory disturbances like hyperalgesia and allodynia. Therapeutic recommendations are antidepressants, antiepileptics, opioids and neuro-stimulation methods.
authors.affiliation: Neurológiai Klinika, Szegedi Tudományegyetem, Szeged, Hungary. tajti.janos@med.u-szeged.hu
authors.forename: Janos
authors.initials: J
authors.lastname: Tajti
authors.forename: Delia
authors.initials: D
authors.lastname: Szok
authors.forename: László
authors.initials: L
authors.lastname: Vécsei
mesh_terms: D000700:Analgesics / Q000627:therapeutic use*; D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use; D000927:Anticonvulsants / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000627:therapeutic use*; D003929:Diabetic Neuropathies / Q000503:physiopathology / Q000628:therapy; D004599:Electric Stimulation Therapy; D005062:European Union; D019317:Evidence-Based Medicine; D006801:Humans; D006930:Hyperalgesia / Q000150:complications / Q000188:drug therapy; D009294:Narcotics / Q000627:therapeutic use; D009437:Neuralgia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy*; D051474:Neuralgia, Postherpetic / Q000503:physiopathology / Q000628:therapy; D059408:Pain Management / Q000379:methods; D010147:Pain Measurement; D017288:Pain Threshold; D010591:Phantom Limb / Q000503:physiopathology / Q000628:therapy; D039781:PubMed; D013119:Spinal Cord Injuries / Q000150:complications / Q000503:physiopathology; D020521:Stroke / Q000150:complications / Q000503:physiopathology; D014277:Trigeminal Neuralgia / Q000503:physiopathology / Q000628:therapy; D014481:United States
chemical_list: D000700:Analgesics; D018712:Analgesics, Non-Narcotic; D000927:Anticonvulsants; D000928:Antidepressive Agents; D009294:Narcotics