title: No evidence for prolonged visible persistence in patients with schizophrenia.
abstract: BACKGROUND
  Temporal visual processing is strongly deteriorated in patients with schizophrenia. For example, the interval required between a visual stimulus and a subsequent mask has to be much longer in schizophrenic patients than in healthy controls. We investigated whether this deficit in temporal resolution is accompanied by prolonged visual persistence and/or deficient temporal precision (temporal asynchrony perception).
  
  
  RESULTS
  We investigated visual persistence in three experiments. In the first, measuring temporal processing by so-called backward masking, prolonged visible persistence is supposed to decrease performance. In the second experiment, requiring temporal integration, prolonged persistence is supposed to improve performance. In the third experiment, we investigated asynchrony detection, as another measure of temporal resolution. Eighteen patients with schizophrenia and 15 healthy controls participated. Asynchrony detection was intact in the patients. However, patients' performance was inferior compared to healthy controls in the first two experiments. Hence, temporal processing in schizophrenic patients is indeed significantly impaired but this impairment is not caused by prolonged temporal integration.
  
  
  CONCLUSIONS
  Our results argue against a generally prolonged visual persistence in patients with schizophrenia. Together with the preserved ability of patients, to detect temporal asynchronies in permanently presented stimuli, the results indicate a more specific deficit in temporal processing of schizophrenic patients.
authors.affiliation: Department of Human Neurobiology, University of Bremen, Bremen, Germany. cgrimsen@uni-bremen.de
authors.forename: Cathleen
authors.initials: C
authors.lastname: Grimsen
authors.forename: Andreas
authors.initials: A
authors.lastname: Brand
authors.forename: Manfred
authors.initials: M
authors.lastname: Fahle
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D006801:Humans; D009483:Neuropsychological Tests; D010470:Perceptual Masking; D012559:Schizophrenia / Q000175:diagnosis / Q000503:physiopathology*; D014792:Visual Acuity; D014796:Visual Perception; D055815:Young Adult
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