title: [Erlotinib-induced acneiform eruption].
abstract: A 73-year-old man has been suffering from a pulmonary adenocarcinoma for three years. He has been treated with the EGF-inhibitor erlotinib for the past 18 months. While taking this medication he developed a progressive papulopustular rash on his face and trunk which later spread to his thighs. Topical treatment with methylprednisolone and nadifloxacin, as well as short courses of systemic doxycycline and ciprofloxacin, led to marked improvement and control of his skin condition.
authors.affiliation: Klinik für Allergologie und Dermatologie, Universitätsklinikum RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany. rwahl@ukaachen.de
authors.forename: R U
authors.initials: RU
authors.lastname: Wahl
authors.forename: M
authors.initials: M
authors.lastname: Megahed
mesh_terms: D017486:Acneiform Eruptions / Q000139:chemically induced* / Q000188:drug therapy* / Q000473:pathology; D000230:Adenocarcinoma / Q000150:complications / Q000188:drug therapy; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D002939:Ciprofloxacin / Q000008:administration & dosage*; D004318:Doxycycline / Q000008:administration & dosage*; D004359:Drug Therapy, Combination / Q000379:methods; D000069347:Erlotinib Hydrochloride; D024841:Fluoroquinolones / Q000008:administration & dosage*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000188:drug therapy; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D011799:Quinazolines / Q000009:adverse effects* / Q000627:therapeutic use; D011807:Quinolizines / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D024841:Fluoroquinolones; D011799:Quinazolines; D011807:Quinolizines; D002939:Ciprofloxacin; C062127:nadifloxacin; D000069347:Erlotinib Hydrochloride; D004318:Doxycycline; D008775:Methylprednisolone
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