title: Spinal cord involvement in a child with familial hemophagocytic lymphohistiocytosis.
abstract: The involvement of the central nervous system (CNS) in familial hemophagocytic lymphohistiocytosis (FHL) has known to be limited to the brain, brain stem, and cerebellum. Herein, we report an 11-year-old boy who presented with neurological symptoms and was diagnosed as FHL by molecular diagnosis. The hemophagocytic lesions in the CNS were shown to extend to the thoracal level of spinal cord which completely disappeared after the completion of hemophagocytic lymphohistiocytosis-2004 protocol.
authors.affiliation: Division of Pediatric Hematology, Hacettepe Medical Faculty, Hacettepe University, Ankara, Turkey.
authors.forename: Muge
authors.initials: M
authors.lastname: Gokce
authors.forename: Gunay
authors.initials: G
authors.lastname: Balta
authors.forename: Sule
authors.initials: S
authors.lastname: Unal
authors.forename: Kader
authors.initials: K
authors.lastname: Oguz
authors.forename: Mualla
authors.initials: M
authors.lastname: Cetin
authors.forename: Fatma
authors.initials: F
authors.lastname: Gumruk
keywords: Central nervous system; UNC13D gene mutation; familial hemophagocytic lymphohistiocytosis; spinal cord involvement
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