title: The concept of rhinorespiratory homeostasis--a new approach to nasal breathing.
abstract: The suggested concept of rhinorespiratory homeostasis is a new theoretical model for the discussion of physiologic and physical principles of nasal breathing. This model is based on a comprehensive view of nasal functions that takes comparative animal physiology into account. Consequently, it has a universal cross-species character and emphasizes the central role of nasal secretion. In contrast to the established view, the focus is transferred from the inspired air to the nasal wall. This concept considers the parietal effect of airflow represented by wall shear stress with special regard to the epithelial lining fluid. It delivers one possible mechanism of an inherent triggering of the nasal cycle. Furthermore, the issue of biological fluid-structure interaction is introduced. This article presents a rethinking of nasal breathing that was inspired by clinical experience and results of flow field investigations through computational fluid dynamics.
authors.affiliation: th@dr-hildebrandt.ch
authors.forename: Thomas
authors.initials: T
authors.lastname: Hildebrandt
authors.forename: Werner Johannes
authors.initials: WJ
authors.lastname: Heppt
authors.forename: Ulrich
authors.initials: U
authors.lastname: Kertzscher
authors.forename: Leonid
authors.initials: L
authors.lastname: Goubergrits
mesh_terms: D000403:Airway Resistance; D000818:Animals; D001833:Body Temperature Regulation; D003398:Craniosynostoses / Q000503:physiopathology*; D006706:Homeostasis; D006801:Humans; D057446:Hydrodynamics; D008322:Mammals; D009296:Nasal Cavity / Q000502:physiology; D009297:Nasal Mucosa / Q000502:physiology; D009666:Nose / Q000502:physiology*; D012123:Pulmonary Ventilation / Q000502:physiology*; D033081:Shear Strength; D013314:Stress, Mechanical; D014420:Turbinates / Q000502:physiology