title: Local complications after industrial liquid silicone injection: case series.
abstract: OBJECTIVE
  To analyze a case series of patients who underwent injection of industrial liquid silicone in a clandestine manner and by unauthorized persons.
  
  
  METHODS
  We conducted a retrospective analysis of medical records of patients treated between September 2003 and December 2010. Data regarding gender, age, location and volume of silicone injected, time between application and clinical manifestations, complications, treatment and outcome were collected. Early manifestations were defined as occurring within 30 days of injection and late manifestations, the ones arising after this period.
  
  
  RESULTS
  We treated 12 patients, eight were male, seven transsexuals. The volume injected ranged from 5 ml to 2000 ml, being unknown in three cases. The most often used injected sites were the thighs and buttocks. Eight patients had early manifestations, with inflammation and/or infection. Surgical debridement was necessary in five cases. Three patients with a history of injection in the breast region underwent adenomastectomy. There was one death due to refractory septic shock.
  
  
  CONCLUSIONS
  The use of industrial liquid silicone should be completely contraindicated as a filling material and modification of body contouring, and may have serious complications, even death.
authors.affiliation: Plastic Surgery Service, Holy House of Mercy of São Paulo - ISCMSP, São Paulo, State of São Paulo - SP, Brazil. mello_plastica@ig.com.br
authors.forename: Daniel Francisco
authors.initials: DF
authors.lastname: Mello
authors.forename: Karen Chicol
authors.initials: KC
authors.lastname: Gonçalves
authors.forename: Murilo F
authors.initials: MF
authors.lastname: Fraga
authors.forename: Luis Fernando
authors.initials: LF
authors.lastname: Perin
authors.forename: Américo
authors.initials: A
authors.lastname: Helene
mesh_terms: D000328:Adult; D003357:Cosmetic Techniques / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012827:Silicone Oils / Q000008:administration & dosage* / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D012827:Silicone Oils