title: Weaning from mechanical ventilation in paediatrics. State of the art.
abstract: Weaning from mechanical ventilation is one of the greatest volume and strength issues in evidence-based medicine in critically ill adults. In these patients, weaning protocols and daily interruption of sedation have been implemented, reducing the duration of mechanical ventilation and associated morbidity. In paediatrics, the information reported is less consistent, so that as yet there are no reliable criteria for weaning and extubation in this patient group. Several indices have been developed to predict the outcome of weaning. However, these have failed to replace clinical judgement, although some additional measurements could facilitate this decision.
authors.affiliation: Facultad de Medicina Clínica Alemana, Universidad del Desarrollo, Santiago, Chile; Área de Cuidados Críticos, Hospital Padre Hurtado, Santiago, Chile. Electronic address: jvalenzuela@hurtadohosp.cl.
authors.forename: Jorge
authors.initials: J
authors.lastname: Valenzuela
authors.affiliation: Área de Cuidados Críticos, Hospital Padre Hurtado, Santiago, Chile.
authors.forename: Patricio
authors.initials: P
authors.lastname: Araneda
authors.affiliation: Área de Cuidados Críticos, Hospital Padre Hurtado, Santiago, Chile; Centro de Investigación de Medicina Veterinaria, Escuela de Medicina Veterinaria, Facultad de Ecología y Recursos Naturales, Universidad Andres Bello, Santiago, Chile.
authors.forename: Pablo
authors.initials: P
authors.lastname: Cruces
mesh_terms: D000293:Adolescent; D000367:Age Factors; D060666:Airway Extubation; D000402:Airway Obstruction / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D045422:Continuous Positive Airway Pressure; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D007442:Intubation, Intratracheal; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D063087:Noninvasive Ventilation; D010808:Physical Examination; D053717:Pneumonia, Ventilator-Associated / Q000517:prevention & control; D011446:Prospective Studies; D012132:Respiratory Muscles / Q000503:physiopathology; D012189:Retrospective Studies; D012307:Risk Factors; D015300:Ventilator Weaning / Q000379:methods* / Q000592:standards; D055397:Ventilator-Induced Lung Injury / Q000517:prevention & control
chemical_list: D006993:Hypnotics and Sedatives; D009125:Muscle Relaxants, Central
keywords: Destete; Extubación; Extubation; Mechanical ventilation; Paediatric; Pediatría; Ventilación mecánica; Weaning