title: Superficial siderosis: A rare occurrence in children.
abstract: Superficial siderosis of the central nervous system results from deposition of hemosiderin in the subpial layers of the brain and spinal cord. Patients usually present after 40 years of age with progressive ataxia and sensorineural hearing impairment. We present the case of a twelve-year-old boy who had a surgery of the posterior fossa at the age of two years and then developed recurrent headaches, instability of gait, and hearing deficit at around ten years of age. Clinical examination revealed progressive ataxia and mild sensorineural hearing loss. He also had infrequent seizures with mild electroencephalographic abnormality. His serial magnetic resonance imaging (MRIs) showed a progressive deposition of hemosiderin in the cerebellar folia and around the brainstem, confirming a diagnosis of superficial siderosis. This case report draws attention to this rare condition, usually seen in adults, even though rarely it can be seen in children as a chronic sequela of surgery of the posterior fossa.
authors.affiliation: Department of Pediatric Neurology, Jaslok Hospital and Research Centre, Mumbai, India.
authors.forename: Trupti M
authors.initials: TM
authors.lastname: Jadhav
authors.forename: Anaita U
authors.initials: AU
authors.lastname: Hegde
keywords: Hemosiderin; posterior fossa; superficial siderosis
references.citation: J Neuropathol Exp Neurol. 1988 May;47(3):249-70
references.pmid: 3367157
references.citation: Ann Neurol. 1993 Nov;34(5):646-53
references.pmid: 8239558
references.citation: AJNR Am J Neuroradiol. 1999 Aug;20(7):1245-8
references.pmid: 10472980
references.citation: Brain. 1995 Aug;118 ( Pt 4):1051-66
references.pmid: 7655881
references.citation: Neuroradiology. 1996 May;38 Suppl 1:S51-6
references.pmid: 8811680
references.citation: AJNR Am J Neuroradiol. 1993 Jan-Feb;14(1):227-36
references.pmid: 8427096
references.citation: J Neurol Neurosurg Psychiatry. 2003 Sep;74(9):1326-8
references.pmid: 12933948
references.citation: J Neurol Neurosurg Psychiatry. 2004 Feb;75(2):188-90
references.pmid: 14742584