title: Recent advances in the molecular and genetic understanding of congenital gastrointestinal malformations.
abstract: Major developmental paradigms are highly conserved among vertebrates. The contribution of developmental biology to the understanding of human disease and regeneration has soared recently. We review advances in the molecular and genetic understanding of gastrointestinal development using evidence from both mammalian and nonmammalian models. When appropriate, we highlight relevance and applicability to human disease.
authors.affiliation: Département de Pédiatrie, Faculté de Médecine, Hôpitaux Universitaires de Genève et Université de Genève, Genève, Switzerland. valerie.mclin@hcuge.ch
authors.forename: Véronique
authors.initials: V
authors.lastname: Dauvé
authors.forename: Valérie A
authors.initials: VA
authors.lastname: McLin
mesh_terms: D000818:Animals; D047109:Fetal Development; D041981:Gastrointestinal Tract / Q000002:abnormalities* / Q000196:embryology / Q000378:metabolism; D006554:Hernia, Umbilical / Q000196:embryology / Q000235:genetics / Q000378:metabolism; D006627:Hirschsprung Disease / Q000196:embryology / Q000235:genetics / Q000378:metabolism; D006801:Humans; D045822:Intestinal Volvulus / Q000196:embryology / Q000235:genetics / Q000378:metabolism; D009154:Mutation