title: A rare case of acute renal failure due to tubulointerstitial nephritis and uveitis syndrome successfully treated with steroid.
abstract: We hereby describe a 49-year-old woman with acute renal failure due to tubulointerstitial nephritis and uveitis (TINU) syndrome. This patient presented with vomiting and nausea and was found to have chronic uveitis, elevated creatinine, and interstitial nephritis. The combination of tubulointerstitial nephritis and uveitis emerged the diagnosis of TINU syndrome after a stepwise examination for differential diagnosis. Clinical course and renal function improved quickly on oral steroids but not to normal range. TINU syndrome, although known to some ophthalmologists and nephrologists, is still rather obscure. TINU syndrome should be considered in patients with uveitis in combination with acute renal failure. The prognosis for the renal disorder is excellent, although the uveitis often recurs or remains chronic.
authors.affiliation: Department of Nephrology, Ankara Numune Research and Education Hospital, Ankara Numune Egitim ve Arastirma Hastanesi Nefroloji Klinigi, 06100 Samanpazan, Ankara, Turkey. drezgi_76@hotmail.com
authors.forename: Ezgi Coskun
authors.initials: EC
authors.lastname: Yenigun
authors.forename: Fatih
authors.initials: F
authors.lastname: Dede
authors.forename: Ramazan
authors.initials: R
authors.lastname: Ozturk
authors.forename: Serhan V
authors.initials: SV
authors.lastname: Piskinpasa
authors.forename: Hadim
authors.initials: H
authors.lastname: Akoglu
authors.forename: Eyup
authors.initials: E
authors.lastname: Koc
authors.forename: Ali Riza
authors.initials: AR
authors.lastname: Odabas
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009395:Nephritis, Interstitial / Q000150:complications* / Q000188:drug therapy*; D011241:Prednisone / Q000627:therapeutic use*; D014605:Uveitis / Q000150:complications* / Q000188:drug therapy*
chemical_list: D000893:Anti-Inflammatory Agents; D011241:Prednisone