title: Vitamin D and multiple sclerosis.
abstract: The role of vitamin D supplementation in preventing multiple sclerosis (MS) and/or treating MS progression is an area of significant research interest. We detail the current status of the ongoing research in this field, and note the lack of class 1 evidence from well-conducted, large, double-blind, placebo-controlled studies of vitamin D supplementation in the prevention and/or treatment of MS. We have been able to provide some guidelines for practitioners based on the substantial burden of supportive evidence for the use of vitamin D in MS as summarised here. These guidelines may provide some support to those clinicians who treat people with MS and their families.
authors.affiliation: Royal Hobart Hospital, Department of Neurology, Hobart, Tasmania, Australia.
authors.forename: Sarah
authors.initials: S
authors.lastname: Hewer
authors.forename: Robyn
authors.initials: R
authors.lastname: Lucas
authors.forename: Ingrid
authors.initials: I
authors.lastname: van der Mei
authors.forename: Bruce V
authors.initials: BV
authors.lastname: Taylor
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000188:drug therapy / Q000517:prevention & control; D006801:Humans; D009103:Multiple Sclerosis / Q000188:drug therapy / Q000517:prevention & control; D017410:Practice Guidelines as Topic / Q000592:standards; D014807:Vitamin D / Q000627:therapeutic use*
chemical_list: D014807:Vitamin D