title: Circadian regulation of kisspeptin in female reproductive functioning.
abstract: Female reproductive functioning requires the precise temporal -organization of numerous neuroendocrine events by a master circadian brain clock located in the suprachiasmatic nucleus. Across species, including humans, disruptions to circadian timing result in pronounced deficits in ovulation and fecundity. The present chapter provides an overview of the circadian control of female reproduction, underscoring the significance of kisspeptin as a key locus of integration for circadian and steroidal signaling necessary for the initiation of ovulation.
authors.affiliation: Department of Psychology, University of California, Berkeley, CA 94720-1650, USA. Kriegsfeld@berkeley.edu
authors.forename: Lance J
authors.initials: LJ
authors.lastname: Kriegsfeld
mesh_terms: D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D005298:Fertility / Q000502:physiology*; D006801:Humans; D059648:Kisspeptins / Q000378:metabolism*; D010060:Ovulation / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D013493:Suprachiasmatic Nucleus / Q000378:metabolism*
chemical_list: C106628:KISS1 protein, human; D059648:Kisspeptins
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