title: Field testing of the Alere DDS2 Mobile Test System for drugs in oral fluid.
abstract: A preliminary field evaluation of a second-generation handheld oral fluid testing device, the Alere DDS2 Mobile Test System (DDS2), is described. As part of a larger study, drivers were randomly stopped at various locations across California (in 2012) and asked to submit voluntarily to a questionnaire regarding their drug and alcohol use, a breath alcohol test and collection of oral fluid with the Quantisal device. The Quantisal-collected oral fluid samples were sent for laboratory-based analyses. At one location, 50 drivers were asked to submit an additional oral fluid sample using the DDS2 collection device; these samples were analyzed by using the DDS2 mobile test system. Thirty-eight donors (76%) provided specimens that were successfully run on the mobile system; in 12 cases (24%), the device failed to provide a valid result. Thirty-two of the 38 collected samples were negative for all drugs; five were positive for tetrahydrocannabinol and one was positive for methamphetamine using the mobile device. These results corresponded exactly with the laboratory-based results from the Quantisal oral fluid collection.
authors.affiliation: Immunalysis Corporation, Pomona, CA 91767, USA. cmoore@immunalysis.com
authors.forename: Christine
authors.initials: C
authors.lastname: Moore
authors.forename: Tara
authors.initials: T
authors.lastname: Kelley-Baker
authors.forename: John
authors.initials: J
authors.lastname: Lacey
mesh_terms: D000434:Alcoholic Beverages / Q000032:analysis; D001334:Automobile Driving; D001944:Breath Tests; D002140:California / Q000453:epidemiology; D002492:Central Nervous System Depressants / Q000032:analysis / Q000378:metabolism; D013759:Dronabinol / Q000032:analysis / Q000378:metabolism; D000431:Ethanol / Q000032:analysis / Q000378:metabolism; D006801:Humans; D013287:Illicit Drugs / Q000032:analysis / Q000378:metabolism*; D008694:Methamphetamine / Q000032:analysis / Q000378:metabolism; D012463:Saliva / Q000737:chemistry / Q000378:metabolism*; D015813:Substance Abuse Detection / Q000295:instrumentation*; D019966:Substance-Related Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000378:metabolism; D011795:Surveys and Questionnaires
chemical_list: D002492:Central Nervous System Depressants; D013287:Illicit Drugs; D000431:Ethanol; D008694:Methamphetamine; D013759:Dronabinol