title: Omega-3 fatty acids in psychiatry.
abstract: Over the past 2 decades, omega-3 fatty acids (n-3FAs) have been increasingly used and studied in the United States and worldwide for various medical and psychiatric indications. Numerous published clinical trials have examined applications of different n-3FA preparations, primarily in mood disorders but also in psychotic disorders, attention-deficit disorder, obsessive-compulsive disorder, and personality disorders. Focusing on clinical issues, this article reviews the impact of n-3FAs on these conditions and covers the relevant research, side effects, dosage guidelines, and drug interactions; clinicians should thus be able to better advise patients who are already taking n-3FAs or are interested in trying them.
authors.affiliation: Depression Clinical and Research Program, Massachusetts General Hospital, Harvard Medical School, 1 Bowdoin Square, 6th Floor, Boston, MA 02114, USA. dmischoulon@partners.org
authors.forename: David
authors.initials: D
authors.lastname: Mischoulon
authors.forename: Marlene P
authors.initials: MP
authors.lastname: Freeman
mesh_terms: D002986:Clinical Trials as Topic; D004281:Docosahexaenoic Acids / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004359:Drug Therapy, Combination / Q000009:adverse effects; D015118:Eicosapentaenoic Acid / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy*
chemical_list: D004281:Docosahexaenoic Acids; D015118:Eicosapentaenoic Acid