title: [Clinical analysis of 45 patients with intracranial germinoma treated by radiotherapy].
abstract: OBJECTIVE
  To report the prospective efficacy of 45 patients intracranial germinoma treated by radiotherapy and discuss its treatment.
  
  
  METHODS
  From February 1998 to October 2007, a total of 45 intracranial germinoma patients were performed radiotherapy, including 15 combined chemotherapy in the Department of Oncology. Of them 23 were pathologically diagnosed while 22 cases were clinical diagnosed. Life table method showed the 5-year and 10-year survival rate.
  
  
  RESULTS
  Forty patients were followed-up. Most symptoms of the patients were significantly reduced or disappeared completely. The 5-year and 10-year survival rate of all patients were 84% and 74%.
  
  
  CONCLUSIONS
  Radiotherapy is the main treatment for intracranial germinoma. Craniospinal irradiation, whole brain irradiation and partial brain irradiation are the main treatments. Radiotherapy combined with chemotherapy, which can reduce the radiation range and dose will be the trend.
authors.affiliation: Department of Oncology,Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Jidong
authors.initials: J
authors.lastname: Hong
authors.forename: Xia
authors.initials: X
authors.lastname: Wang
authors.forename: Yuping
authors.initials: Y
authors.lastname: Peng
authors.forename: Longyun
authors.initials: L
authors.lastname: Wang
authors.forename: Lei
authors.initials: L
authors.lastname: Huo
authors.forename: Zaide
authors.initials: Z
authors.lastname: Han
authors.forename: Qingsong
authors.initials: Q
authors.lastname: Tu
mesh_terms: D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy*; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D018237:Germinoma / Q000188:drug therapy / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents