title: Relationship between the morphology of diabetic macular edema and renal dysfunction in diabetes.
abstract: OBJECTIVE
  To determine the correlation between renal dysfunction and the morphologic changes of macular edema in diabetes.
  
  
  METHODS
  The current study included 93 patients with diabetic macular edema based on optical coherence tomography (OCT) who completed systemic condition testing one month before or after the OCT. Based on the OCT findings, patients were divided into the following five groups: group A (diffuse), group B (cystoid), group C (serous), group D (vitreomacular tractional), and group E (a mixed presence of cystoid and serous types). In each group, we performed a retrospective analysis of serum albumin, urine albumin, and serum creatinine. We also analyzed the patients in whom serum albumin was <3.0 mg/dL and serum creatinine was >1.6 mg/dL. Urine albumin was measured in all five groups. In each group, a comparative analysis was performed using Fisher's exact test.
  
  
  RESULTS
  The number of patients who were assigned to groups A to E was 15, 46, 6, 3, and 23, respectively. According to a comparison of the patients in whom the serum albumin and serum creatinine were abnormal, there was no significant difference among the five groups. The proportion of patients in whom the urine albumin was abnormal was significantly greater in group C (67%) than in groups A (7%), B (20%), or E (22%).
  
  
  CONCLUSIONS
  Serous-type macular edema occurred more frequently than other types of macular edema in patients with albuminuria.
authors.affiliation: Department of Ophthalmology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
authors.forename: Nam Kyun
authors.initials: NK
authors.lastname: Koo
authors.forename: Hyun Cheol
authors.initials: HC
authors.lastname: Jin
authors.forename: Kwang Soo
authors.initials: KS
authors.lastname: Kim
authors.forename: Yu Cheol
authors.initials: YC
authors.lastname: Kim
mesh_terms: D000368:Aged; D003928:Diabetic Nephropathies / Q000473:pathology*; D003930:Diabetic Retinopathy / Q000473:pathology*; D005260:Female; D006801:Humans; D008269:Macular Edema / Q000145:classification* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence
keywords: Macular edema; Optical coherence tomography
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