title: Trends in nanopharmaceutical patents.
abstract: Investment in nanotechnology is now a given constant by governments, research centers and companies in both more developed countries and emerging markets. Due to their characteristics, such as high stability, ability to enable antigen identification on specific cells in the human body and controlling the release of drugs and, therefore, improving therapies, nanoparticles have been the subject of research and patent applications in the pharmaceutical field. According to the Organization for Economic Co-operation and Development (OCDE), patent data can be used as a source of information in order to measure science and technology activities. Thereby, this paper presents an analysis based on patent documents related to nanotechnology in the pharmaceutical sector. As a result, the analysis of patents demonstrate primarily that nanobiotechnology attracts high levels of R&amp;D investments, including nanoparticle-based chemotherapeutic agents/drugs, monoclonal antibody nanoparticle complexes and their role in drug delivery or contrast agents with non-toxic effects.
authors.affiliation: National Institute of Industrial Property (Brazil), Mayrink Veiga, n° 9 Centro, Rio de Janeiro, Brazil. aantunes@inpi.gov.br.
authors.forename: Adelaide
authors.initials: A
authors.lastname: Antunes
authors.forename: Iolanda
authors.initials: I
authors.lastname: Fierro
authors.forename: Rafaela
authors.initials: R
authors.lastname: Guerrante
authors.forename: Flavia
authors.initials: F
authors.lastname: Mendes
authors.forename: Maria Simone
authors.initials: MS
authors.lastname: de M Alencar
mesh_terms: D003952:Diagnostic Imaging; D016503:Drug Delivery Systems; D006801:Humans; D050997:Nanomedicine / Q000639:trends*; D053758:Nanoparticles / Q000633:toxicity; D009369:Neoplasms / Q000188:drug therapy; D010330:Patents as Topic; D018675:Toxicity Tests
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references.pmid: 17379166
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