title: Anabolic resistance of muscle protein synthesis with aging.
abstract: Aging has been associated with a reduced muscle protein synthetic response to protein intake, termed "anabolic resistance." Physical activity performed before protein intake increases the use of protein-derived amino acids for postprandial muscle protein accretion in senescent muscle. Thus, the level of habitual physical activity may be fundamental to maintain the anabolic responsiveness to protein intake with aging.
authors.affiliation: Department of Human Movement Sciences, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands.
authors.forename: Nicholas A
authors.initials: NA
authors.lastname: Burd
authors.forename: Stefan H
authors.initials: SH
authors.lastname: Gorissen
authors.forename: Luc J C
authors.initials: LJ
authors.lastname: van Loon
mesh_terms: D000375:Aging / Q000502:physiology*; D000596:Amino Acids / Q000097:blood; D004435:Eating; D015444:Exercise / Q000502:physiology*; D006801:Humans; D009124:Muscle Proteins / Q000096:biosynthesis*; D019518:Postprandial Period / Q000502:physiology*
chemical_list: D000596:Amino Acids; D009124:Muscle Proteins