title: DIOS - database of formalized chemotherapeutic regimens.
abstract: Chemotherapeutic regimens (CHR) and their administration are routine practice in contemporary oncology. The development of a structured, electronic database of standard CHR can help the faster propagation of information about new CHR and at the same time enable assessment of their adherence in clinical practice. The goal was to develop a standardized way to describe a regimen using XML, fill the database with currently available regimens and develop tools to assess the adherence of the treatment to chosen regimen, compare the dose-intensity and recognize the regimen from existing data on drug administration. The data are being inserted in cooperation with expert oncologists and the database currently contains about 260 CHRs. Such system can be used to enhance decision support systems and interoperability of HIS. The database and tools are available online on the internet.
authors.affiliation: Institute of Biostatistics and Analyses, Masaryk University, Brno, Czech Republic. klimes@iba.muni.cz
authors.forename: Daniel
authors.initials: D
authors.lastname: Klimes
authors.forename: Roman
authors.initials: R
authors.lastname: Smid
authors.forename: Miroslav
authors.initials: M
authors.lastname: Kubasek
authors.forename: Rostislav
authors.initials: R
authors.lastname: Vyzula
authors.forename: Ladislav
authors.initials: L
authors.lastname: Dušek
mesh_terms: D003628:Database Management Systems; D062313:Databases, Pharmaceutical; D020000:Decision Support Systems, Clinical; D004358:Drug Therapy; D016247:Information Storage and Retrieval / Q000379:methods*; D020407:Internet; D014584:User-Computer Interface