title: Common endocrine issues in the pediatric intensive care unit.
abstract: Thyroid hormone is central to normal development and metabolism. Abnormalities in thyroid function in North America often arise from autoimmune diseases, but they rarely present as critical illness. Severe deficiency or excess of thyroid hormone both represent life-threatening disease, which must be treated expeditiously and thoroughly. Such deficiencies must be considered, because presentation may be nonspecific.
authors.affiliation: Seattle Children's Hospital, University of Washington School of Medicine, 4800 Sand Point Way NE, Seattle, WA 98105, USA.
authors.forename: Amelie
authors.initials: A
authors.lastname: von Saint Andre-von Arnim
authors.forename: Reid
authors.initials: R
authors.lastname: Farris
authors.forename: Joan S
authors.initials: JS
authors.lastname: Roberts
authors.forename: Ofer
authors.initials: O
authors.lastname: Yanay
authors.forename: Thomas V
authors.initials: TV
authors.lastname: Brogan
authors.forename: Jerry J
authors.initials: JJ
authors.lastname: Zimmerman
mesh_terms: D000305:Adrenal Cortex Hormones / Q000172:deficiency*; D000804:Angiotensin II / Q000502:physiology; D001929:Brain Edema / Q000209:etiology*; D002648:Child; D016638:Critical Illness; D016883:Diabetic Ketoacidosis / Q000150:complications* / Q000175:diagnosis / Q000209:etiology; D004700:Endocrine System Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D005067:Euthyroid Sick Syndromes / Q000150:complications / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans; D018836:Inflammation Mediators / Q000502:physiology; D015278:Intensive Care Units, Pediatric; D008660:Metabolism / Q000502:physiology; D010275:Parasympathetic Nervous System / Q000502:physiology; D013312:Stress, Physiological; D013564:Sympathetic Nervous System / Q000502:physiology; D013963:Thyroid Hormones / Q000172:deficiency; D014883:Water-Electrolyte Imbalance / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy
chemical_list: D000305:Adrenal Cortex Hormones; D018836:Inflammation Mediators; D013963:Thyroid Hormones; D000804:Angiotensin II