title: Liver transplant for cholestatic liver diseases.
abstract: Cholestatic liver diseases include a group of diverse disorders with different epidemiology, pathophysiology, clinical course, and prognosis. Despite significant advances in the clinical care of patients with cholestatic liver diseases, liver transplant (LT) remains the only definitive therapy for end-stage liver disease, regardless of the underlying cause. As per the United Network for Organ Sharing database, the rate of cadaveric LT for cholestatic liver disease was 18% in 1991, 10% in 2000, and 7.8% in 2008. This review summarizes the available evidence on various common and rare cholestatic liver diseases, disease-specific issues, and pertinent aspects of LT.
authors.affiliation: Division of Gastroenterology, Department of Medicine, University of Miami Miller School of Medicine, 1120 Northwest 14th Street, Suite 310E, Miami, FL 33136, USA.
authors.forename: Andres F
authors.initials: AF
authors.lastname: Carrion
authors.forename: Kalyan Ram
authors.initials: KR
authors.lastname: Bhamidimarri
mesh_terms: D016738:Alagille Syndrome / Q000601:surgery; D001656:Biliary Atresia / Q000150:complications / Q000601:surgery; D015209:Cholangitis, Sclerosing / Q000150:complications / Q000601:surgery*; D002779:Cholestasis / Q000209:etiology / Q000601:surgery*; D002780:Cholestasis, Intrahepatic / Q000601:surgery; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000601:surgery; D016031:Liver Transplantation; D010289:Parenteral Nutrition, Total / Q000009:adverse effects*; D018579:Patient Selection; D012008:Recurrence; D012507:Sarcoidosis / Q000150:complications / Q000601:surgery