title: Vascular calcification in a young patient with end-stage renal disease.
abstract: Vascular calcification in children with long-standing dialysis is a unique phenomenon. Hyperphosphataemia and hyperparathyroidism are the major pathogenic risk factors. We describe a young patient with end-stage renal disease diagnosed since childhood and underwent prolonged dialysis therapy. He was admitted for recurrent episodes of acute joint pain. Investigations confirmed diffuse periarticular, vascular, and intracardiac calcifications which were rarely seen in the young population. He underwent parathyroidectomy and incidentally found to have a co-existing papillary carcinoma of thyroid. After parathyroidectomy, serial X-rays showed resorption of these calcifications.
authors.affiliation: Department of Paediatrics, Queen Elizabeth Hospital, Jordan, Hong Kong. chankyw@ha.org.hk
authors.forename: Winnie K Y
authors.initials: WK
authors.lastname: Chan
authors.forename: K W
authors.initials: KW
authors.lastname: Lee
authors.forename: W M
authors.initials: WM
authors.lastname: But
authors.forename: K F
authors.initials: KF
authors.lastname: Chau
mesh_terms: D001774:Blood Chemical Analysis; D002318:Cardiovascular Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy; D002675:Child, Preschool; D015150:Echocardiography, Doppler / Q000379:methods; D005500:Follow-Up Studies; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D054559:Hyperphosphatemia / Q000209:etiology / Q000503:physiopathology; D033162:Incidental Findings; D007676:Kidney Failure, Chronic / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000503:physiopathology; D008297:Male; D016105:Parathyroidectomy / Q000379:methods; D010530:Peritoneal Dialysis / Q000009:adverse effects / Q000379:methods; D018570:Risk Assessment; D013964:Thyroid Neoplasms / Q000473:pathology / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods; D061205:Vascular Calcification / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D014955:Wrist Joint / Q000000981:diagnostic imaging / Q000503:physiopathology
keywords: Kidney failure, chronic; Vascular diseases