title: Rapid induction of an immune response in rat Peyer's patch after oral administration of Enterococcus faecalis strain EC-12.
abstract: A rapid and sharp immune response induced in Peyer's patches (PPs) by a single gavage of a heat-killed Enterococcus faecalis strain EC-12 (EC-12) was demonstrated. EC-12 was observed inside the PPs 2.5 h post administration and induction of TNF-α and CD69 gene expression was observed at the same time. The immune response in PPs disappeared 24 h post administration.
authors.affiliation: Kyoto Institute of Nutrition & Pathology, Kyoto, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Inoue
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Tsukahara
authors.forename: Noriko
authors.initials: N
authors.lastname: Matsukawa
authors.forename: Takumi
authors.initials: T
authors.lastname: Watanabe
authors.forename: Wakoto
authors.initials: W
authors.lastname: Bukawa
authors.forename: Keizo
authors.initials: K
authors.lastname: Nakayama
authors.forename: Kazunari
authors.initials: K
authors.lastname: Ushida
mesh_terms: D000284:Administration, Oral; D000818:Animals; D016207:Cytokines / Q000235:genetics / Q000378:metabolism; D013293:Enterococcus faecalis / Q000502:physiology*; D005786:Gene Expression Regulation / Q000276:immunology; D006358:Hot Temperature; D056747:Immunomodulation; D008297:Male; D050296:Microbial Viability; D010581:Peyer's Patches / Q000276:immunology* / Q000378:metabolism / Q000382:microbiology*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
chemical_list: D016207:Cytokines