title: Feasibility, acceptability and preliminary efficacy of an online peer-to-peer social support ART adherence intervention.
abstract: This study describes the results of an online social support intervention, called "Thrive with Me" (TWM), to improve antiretroviral therapy (ART) adherence. HIV-positive gay or bisexually-identified men self-reporting imperfect ART adherence in the past month were randomized to receive usual care (n = 57) or the eight-week TWM intervention (n = 67). Self-reported ART outcome measures (0-100 % in the past month) were collected at baseline, post-intervention, and 1-month follow-up. Follow-up assessment completion rate was 90%. Participants rated (1-7 scale) the intervention high in information and system quality and overall satisfaction (Means ≥ 5.0). The intervention showed modest effects for the overall sample. However, among current drug-using participants, the TWM (vs. Control) group reported significantly higher overall ART adherence (90.1 vs. 57.5% at follow-up; difference = 31.1, p = 0.02) and ART taken correctly with food (81.6 vs. 55.7% at follow-up; difference = 47.9, p = 0.01). The TWM intervention appeared feasible to implement, acceptable to users, and demonstrated greatest benefits for current drug users.
authors.affiliation: Center for AIDS Intervention Research, Medical College of Wisconsin, 2071 N. Summit Ave., Milwaukee, WI 53202, USA. khorvath@mcw.edu
authors.forename: Keith J
authors.initials: KJ
authors.lastname: Horvath
authors.forename: J Michael
authors.initials: JM
authors.lastname: Oakes
authors.forename: B R Simon
authors.initials: BR
authors.lastname: Rosser
authors.forename: Gene
authors.initials: G
authors.lastname: Danilenko
authors.forename: Heather
authors.initials: H
authors.lastname: Vezina
authors.forename: K Rivet
authors.initials: KR
authors.lastname: Amico
authors.forename: Mark L
authors.initials: ML
authors.lastname: Williams
authors.forename: Jane
authors.initials: J
authors.lastname: Simoni
mesh_terms: D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use*; D001727:Bisexuality; D005240:Feasibility Studies; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology; D018451:Homosexuality, Male; D006801:Humans; D020407:Internet; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D017060:Patient Satisfaction; D010379:Peer Group; D012944:Social Support
chemical_list: D019380:Anti-HIV Agents
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