title: Cardioprotective effect of resveratrol and resveratroloside.
abstract: Cardioprotective effect of resveratrol and resveratroloside was determined in ischemia-reperfusion experiments on rats. It was found that single intraperitoneal administration of any compound (10 mg/kg) followed by 30-min ischemia and 120-min reperfusion resulted in statistically significant decrease of myocardial infarct area (55.0±4.0% for control group; 40.7±4.4% for the group 1 received resveratrol; 41.6±4.8% for the group 2 received resveratroloside). The cardioprotective effect of resveratroloside was detected for the first time.
authors.forename: Sergey E
authors.initials: SE
authors.lastname: Naumenko
authors.forename: Tatiana V
authors.initials: TV
authors.lastname: Latysheva
authors.forename: Michael A
authors.initials: MA
authors.lastname: Gilinsky
authors.forename: Artem D
authors.initials: AD
authors.lastname: Rogachev
authors.forename: Nina I
authors.initials: NI
authors.lastname: Komarova
authors.forename: Nariman F
authors.initials: NF
authors.lastname: Salakhutdinov
authors.affiliation: Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 630090, Novosibirsk, Russia. rogachev@nioch.nsc.ru.
authors.forename: Genrikh A
authors.initials: GA
authors.lastname: Tolstikov
mesh_terms: D000818:Animals; D002316:Cardiotonic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005960:Glucosides / Q000737:chemistry / Q000627:therapeutic use*; D007263:Infusions, Parenteral; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy*; D051381:Rats; D017208:Rats, Wistar; D012015:Reference Standards; D000077185:Resveratrol; D013267:Stilbenes / Q000737:chemistry / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: C000592752:3,5,4'-trihydroxystilbene-4'-O-glucoside; D002316:Cardiotonic Agents; D005960:Glucosides; D013267:Stilbenes; D000077185:Resveratrol