title: Comparison of phenylephrine administration and exercise versus phenylephrine administration and a rolling procedure for the correction of nephrosplenic entrapment of the large colon in horses: 88 cases (2004-2010).
abstract: OBJECTIVE
  To compare the outcome of horses with nephrosplenic entrapment of the large colon (NSELC) that were treated nonsurgically by IV administration of phenylephrine and exercise with that of horses treated by IV administration of phenylephrine and a rolling procedure under general anesthesia.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  88 horses with NSELC.
  
  
  METHODS
  Horses examined between 2004 and 2010 because of acute abdominal pain that had NSELC on the basis of findings on abdominal palpation per rectum, abdominal ultrasonography, or both were included. Medical records were reviewed to obtain information on treatment (IV administration of phenylephrine and exercise vs IV administration of phenylephrine and a rolling procedure) and outcome.
  
  
  RESULTS
  Overall, 85% (75/88) of horses with NSELC responded to exercise or rolling under general anesthesia. The success rate of rolling under general anesthesia (42/50 [84%]) was significantly higher than the success rate of exercise after IV administration of phenylephrine (24/38 [63.2%]). Resolution of NSELC was achieved by rolling under general anesthesia in 8 of 14 horses that initially failed to resolve with exercise.
  
  
  CONCLUSIONS
  A rolling procedure performed under general anesthesia had a higher success rate than exercise after IV phenylephrine administration for resolution of NSELC in horses, suggesting that rolling could be considered as the initial medical treatment. The rolling procedure may be labor intensive and should only be attempted in a surgical facility in the event that exploratory laparotomy is required.
authors.affiliation: Equine Medical Center of Ocala, 7107 W. Highway 326, Ocala, FL 34482, USA.
authors.forename: Lisa E
authors.initials: LE
authors.lastname: Fultz
authors.forename: John G
authors.initials: JG
authors.lastname: Peloso
authors.forename: Steeve
authors.initials: S
authors.lastname: Giguère
authors.forename: Aric R
authors.initials: AR
authors.lastname: Adams
mesh_terms: D000768:Anesthesia, General / Q000662:veterinary; D000818:Animals; D003106:Colon / Q000473:pathology*; D006734:Horse Diseases / Q000628:therapy*; D006736:Horses; D007415:Intestinal Obstruction / Q000628:therapy / Q000662:veterinary*; D010656:Phenylephrine / Q000627:therapeutic use*; D010805:Physical Conditioning, Animal; D012189:Retrospective Studies; D013566:Sympathomimetics / Q000627:therapeutic use*
chemical_list: D013566:Sympathomimetics; D010656:Phenylephrine