title: Assistant DNA recycling with nicking endonuclease and molecular beacon for signal amplification using a target-complementary arched structure.
abstract: A simple and universal method for ultrasensitive "signal on" detection of DNA was developed with a target-complementary arched structure to release assistant DNA, which was recycled with nicking endonuclease to amplify the detectable fluorescent signal of molecular beacons.
authors.affiliation: State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, PR China.
authors.forename: Fenglei
authors.initials: F
authors.lastname: Gao
authors.forename: Jianping
authors.initials: J
authors.lastname: Lei
authors.forename: Huangxian
authors.initials: H
authors.lastname: Ju
mesh_terms: D020137:Base Pair Mismatch; D004247:DNA / Q000032:analysis* / Q000378:metabolism; D004720:Endonucleases / Q000378:metabolism; D005456:Fluorescent Dyes / Q000032:analysis; D057230:Limit of Detection; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D004247:DNA; D004720:Endonucleases