title: Auxin: a master regulator in plant root development.
abstract: The demand for increased crop productivity and the predicted challenges related to plant survival under adverse environmental conditions have renewed the interest in research in root biology. Various physiological and genetic studies have provided ample evidence in support of the role of plant growth regulators in root development. The biosynthesis and transport of auxin and its signaling play a crucial role in controlling root growth and development. The univocal role of auxin in root development has established it as a master regulator. Other plant hormones, such as cytokinins, brassinosteroids, ethylene, abscisic acid, gibberellins, jasmonic acid, polyamines and strigolactones interact either synergistically or antagonistically with auxin to trigger cascades of events leading to root morphogenesis and development. In recent years, the availability of biological resources, development of modern tools and experimental approaches have led to the advancement of knowledge in root development. Research in the areas of hormone signal perception, understanding network of events involved in hormone action and the transport of plant hormones has added a new dimension to root biology. The present review highlights some of the important conceptual developments in the interplay of auxin and other plant hormones and associated downstream events affecting root development.
authors.affiliation: Department of Biotechnology, Guru Nanak Dev University, Amritsar 143005, India.
authors.forename: Shivani
authors.initials: S
authors.lastname: Saini
authors.forename: Isha
authors.initials: I
authors.lastname: Sharma
authors.forename: Navdeep
authors.initials: N
authors.lastname: Kaur
authors.forename: Pratap Kumar
authors.initials: PK
authors.lastname: Pati
mesh_terms: D001692:Biological Transport; D018506:Gene Expression Regulation, Plant; D007210:Indoleacetic Acids / Q000378:metabolism*; D063245:Plant Development; D010937:Plant Growth Regulators / Q000378:metabolism*; D018517:Plant Roots / Q000235:genetics / Q000254:growth & development* / Q000502:physiology; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D007210:Indoleacetic Acids; D010937:Plant Growth Regulators
references.citation: Curr Opin Plant Biol. 2010 Feb;13(1):21-6
references.pmid: 19850510
references.citation: Development. 2011 Aug;138(16):3485-95
references.pmid: 21771812
references.citation: Plant J. 2003 Dec;36(5):643-51
references.pmid: 14617065
references.citation: Plant Cell. 2007 Jul;19(7):2169-85
references.pmid: 17630276
references.citation: Bioessays. 2009 Jan;31(1):60-70
references.pmid: 19154004
references.citation: Plant Cell. 2005 Jun;17(6):1685-703
references.pmid: 15894717
references.citation: Plant Mol Biol. 2002 Jun-Jul;49(3-4):411-26
references.pmid: 12036264
references.citation: Trends Plant Sci. 2012 Apr;17(4):181-95
references.pmid: 22406007
references.citation: Plant J. 2008 Jul;55(2):175-87
references.pmid: 18363780
references.citation: Plant Cell. 2007 Jan;19(1):118-30
references.pmid: 17259263
references.citation: Plant J. 1998 Jan;13(2):231-9
references.pmid: 9680979
references.citation: Plant Cell. 1996 Sep;8(9):1505-17
references.pmid: 8837505
references.citation: Plant Cell. 2005 Oct;17(10):2738-53
references.pmid: 16141452
references.citation: Plant Cell. 2006 Jan;18(1):40-54
references.pmid: 16361392
references.citation: Curr Opin Plant Biol. 2006 Oct;9(5):448-53
references.pmid: 16877027
references.citation: Nat Chem Biol. 2008 Jun;4(6):337-9
references.pmid: 18488010
references.citation: Curr Opin Plant Biol. 2007 Oct;10(5):453-60
references.pmid: 17900969
references.citation: Plant Cell Environ. 2013 May;36(5):945-55
references.pmid: 23078108
references.citation: Plant Physiol. 1982 Mar;69(3):701-6
references.pmid: 16662279
references.citation: Plant Cell. 2010 Nov;22(11):3560-73
references.pmid: 21097710
references.citation: Genes Dev. 2001 Oct 15;15(20):2648-53
references.pmid: 11641271
references.citation: Plant J. 2002 Jan;29(2):153-68
references.pmid: 11862947
references.citation: Plant Cell. 2009 May;21(5):1495-511
references.pmid: 19435934
references.citation: Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4489-94
references.pmid: 18337510
references.citation: Cell. 1996 Apr 19;85(2):171-82
references.pmid: 8612270
references.citation: Plant Cell. 2010 Sep;22(9):2956-69
references.pmid: 20823193
references.citation: Curr Opin Plant Biol. 1998 Oct;1(5):434-9
references.pmid: 10066623
references.citation: Biosci Biotechnol Biochem. 2006 Apr;70(4):768-73
references.pmid: 16636440
references.citation: Genes Dev. 1998 Jul 15;12(14):2175-87
references.pmid: 9679062
references.citation: Nature. 2008 Nov 27;456(7221):520-3
references.pmid: 19037316
references.citation: J Biol Chem. 1995 Aug 11;270(32):19093-9
references.pmid: 7642574
references.citation: Plant J. 2000 Nov;24(3):327-33
references.pmid: 11069706
references.citation: Trends Plant Sci. 2007 Oct;12(10):474-81
references.pmid: 17822944
references.citation: Plant Cell. 2006 Feb;18(2):308-20
references.pmid: 16377756
references.citation: Trends Cell Biol. 2007 Oct;17(10):485-92
references.pmid: 17904848
references.citation: Plant Physiol. 2006 Apr;140(4):1384-96
references.pmid: 16489132
references.citation: J Exp Bot. 2011 Oct;62(14):5131-47
references.pmid: 21778177
references.citation: Annu Rev Plant Biol. 2008;59:443-65
references.pmid: 18444904
references.citation: Proc Natl Acad Sci U S A. 2009 May 12;106(19):8073-6
references.pmid: 19416891
references.citation: Development. 2003 Dec;130(23):5769-77
references.pmid: 14534134
references.citation: Nature. 2009 Jun 25;459(7250):1071-8
references.pmid: 19553990
references.citation: Philos Trans R Soc Lond B Biol Sci. 2012 Jun 5;367(1595):1469-78
references.pmid: 22527389
references.citation: Trends Plant Sci. 2009 Jul;14(7):399-408
references.pmid: 19559642
references.citation: Plant Cell. 2003 Dec;15(12):2979-91
references.pmid: 14630970
references.citation: Plant Cell. 2001 Oct;13(10):2349-60
references.pmid: 11595806
references.citation: Trends Plant Sci. 2008 Feb;13(2):85-92
references.pmid: 18262459
references.citation: Plant Cell Physiol. 2001 Mar;42(3):301-7
references.pmid: 11266581
references.citation: Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2992-7
references.pmid: 12606727
references.citation: Plant Mol Biol. 2002 Jun-Jul;49(3-4):387-400
references.pmid: 12036262
references.citation: Trends Plant Sci. 2006 Aug;11(8):382-6
references.pmid: 16839804
references.citation: Curr Opin Plant Biol. 2011 Feb;14(1):10-6
references.pmid: 20926335
references.citation: Nature. 2006 Sep 28;443(7110):458-61
references.pmid: 17006513
references.citation: New Phytol. 2011 May;190(3):545-9
references.pmid: 21638793
references.citation: Mol Gen Genet. 1990 Jul;222(2-3):377-83
references.pmid: 2148800
references.citation: PLoS Genet. 2011 Jul;7(7):e1002172
references.pmid: 21779177
references.citation: Plant Cell. 2001 Dec;13(12):2809-22
references.pmid: 11752389
references.citation: Plant Cell. 2010 Mar;22(3):623-39
references.pmid: 20354195
references.citation: J Exp Bot. 2010 Jun;61(10):2719-33
references.pmid: 20472577
references.citation: Curr Biol. 2011 Jun 21;21(12):1055-60
references.pmid: 21658946
references.citation: Planta. 2005 Sep;222(1):98-106
references.pmid: 15889272
references.citation: Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10185-90
references.pmid: 12114546
references.citation: Nature. 2001 Nov 15;414(6861):271-6
references.pmid: 11713520
references.citation: Plant J. 2008 Jul;55(2):335-47
references.pmid: 18435826
references.citation: FEBS Lett. 2006 Feb 13;580(4):1094-102
references.pmid: 16359667
references.citation: Plant J. 2011 May;66(4):564-78
references.pmid: 21284753
references.citation: Curr Biol. 2007 Apr 17;17(8):678-82
references.pmid: 17363254
references.citation: Annu Rev Cell Dev Biol. 2008;24:447-73
references.pmid: 18837671
references.citation: Plant J. 2010 Jan;61(1):3-15
references.pmid: 19793078
references.citation: Trends Plant Sci. 2012 Oct;17(10):594-605
references.pmid: 22738940
references.citation: Trends Plant Sci. 2010 Apr;15(4):219-26
references.pmid: 20153971
references.citation: Plant Physiol. 1990 Nov;94(3):1462-6
references.pmid: 16667854
references.citation: Science. 2001 Nov 16;294(5546):1519-21
references.pmid: 11691951
references.citation: Cell. 2009 Mar 20;136(6):1005-16
references.pmid: 19303845
references.citation: Plant Cell. 2012 Jan;24(1):15-20
references.pmid: 22227890
references.citation: Curr Opin Plant Biol. 2009 Oct;12(5):527-38
references.pmid: 19740698
references.citation: Trends Plant Sci. 2003 Oct;8(10):492-7
references.pmid: 14557046
references.citation: Genes Dev. 1998 Jan 15;12(2):198-207
references.pmid: 9436980
references.citation: Plant Physiol. 2005 Jun;138(2):1117-25
references.pmid: 15908602
references.citation: Plant J. 2006 Jan;45(2):193-205
references.pmid: 16367964
references.citation: J Exp Bot. 2002 Jun;53(373):1463-73
references.pmid: 12021294
references.citation: Plant Cell. 2011 Jun;23(6):2184-95
references.pmid: 21642547
references.citation: Plant Physiol. 2001 Feb;125(2):519-22
references.pmid: 11161008
references.citation: Nat Cell Biol. 2008 May;10(5):625-8
references.pmid: 18425113
references.citation: Plant Signal Behav. 2012 Jan;7(1):68-70
references.pmid: 22231282
references.citation: Cold Spring Harb Perspect Biol. 2010 Mar;2(3):a001552
references.pmid: 20300209
references.citation: Planta. 2011 Jan;233(1):209-16
references.pmid: 21080198
references.citation: Nature. 1998 Oct 15;395(6703):716-20
references.pmid: 9790195
references.citation: Cold Spring Harb Perspect Biol. 2010 Jun;2(6):a001537
references.pmid: 20516130
references.citation: Plant Cell. 2012 Jun;24(6):2515-27
references.pmid: 22730403
references.citation: Trends Plant Sci. 2007 Apr;12(4):160-8
references.pmid: 17369077
references.citation: Tree Physiol. 1996 May;16(5):515-9
references.pmid: 14871722
references.citation: Plant J. 2003 Feb;33(3):543-55
references.pmid: 12581312
references.citation: J Exp Bot. 2011 Feb;62(4):1399-409
references.pmid: 21196475
references.citation: Plant J. 2010 Mar;61(6):992-1000
references.pmid: 20409273
references.citation: Nature. 2005 Sep 29;437(7059):693-8
references.pmid: 16193045
references.citation: Plant Cell. 2007 Jun;19(6):1838-50
references.pmid: 17557805
references.citation: Plant Physiol. 2002 Dec;130(4):1974-82
references.pmid: 12481080
references.citation: Plant Cell. 2009 Dec;21(12):3839-49
references.pmid: 20040538
references.citation: Plant Cell. 2005 Nov;17(11):3007-18
references.pmid: 16227453
references.citation: Plant J. 1997 Jul;12(1):9-19
references.pmid: 9263448
references.citation: Cell. 2007 Sep 21;130(6):1044-56
references.pmid: 17889649
references.citation: Mol Plant. 2009 Jul;2(4):823-831
references.pmid: 19825657
references.citation: Plant Physiol. 1999 Sep;121(1):53-60
references.pmid: 10482660
references.citation: J Exp Bot. 2011 Jun;62(10):3273-88
references.pmid: 21212299
references.citation: Nature. 2005 May 26;435(7041):446-51
references.pmid: 15917798
references.citation: Nature. 2003 Feb 13;421(6924):740-3
references.pmid: 12610625
references.citation: Trends Plant Sci. 2003 Apr;8(4):165-71
references.pmid: 12711228
references.citation: Plant Cell. 2007 Mar;19(3):831-46
references.pmid: 17369372
references.citation: Genetics. 2001 Oct;159(2):767-76
references.pmid: 11606551
references.citation: Plant Physiol. 2006 Oct;142(2):553-63
references.pmid: 16905669
references.citation: Plant Cell. 2007 Jul;19(7):2197-212
references.pmid: 17630274
references.citation: Cell. 2008 Apr 4;133(1):177-91
references.pmid: 18394997
references.citation: Cell. 2004 Oct 1;119(1):109-20
references.pmid: 15454085
references.citation: Plant Cell. 2007 Jul;19(7):2186-96
references.pmid: 17630275
references.citation: Trends Plant Sci. 2005 Apr;10(4):170-7
references.pmid: 15817418
references.citation: Plant J. 2009 Mar;57(6):975-85
references.pmid: 19000167
references.citation: Science. 1996 Aug 16;273(5277):948-50
references.pmid: 8688077
references.citation: Plant Cell. 2005 Apr;17(4):1090-104
references.pmid: 15772288
references.citation: Plant Cell. 2004 Mar;16(3):658-71
references.pmid: 14973166
references.citation: Plant J. 2003 Apr;34(1):67-75
references.pmid: 12662310
references.citation: Development. 2004 Feb;131(3):657-68
references.pmid: 14711878
references.citation: Genes Dev. 2002 Dec 1;16(23):3100-12
references.pmid: 12464638
references.citation: Plant Physiol. 1998 Oct;118(2):341-7
references.pmid: 9765520
references.citation: Cold Spring Harb Perspect Biol. 2010 Jan;2(1):a001594
references.pmid: 20182605
references.citation: Plant Signal Behav. 2008 Apr;3(4):272-4
references.pmid: 19704652
references.citation: Plant J. 1998 Dec;16(5):553-60
references.pmid: 10036773
references.citation: Plant Physiol. 2004 Apr;134(4):1624-31
references.pmid: 15047895
references.citation: Mol Plant. 2011 Jul;4(4):588-600
references.pmid: 21471332
references.citation: Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11795-800
references.pmid: 11573012
references.citation: Genetics. 2001 Oct;159(2):777-85
references.pmid: 11606552
references.citation: Nat Rev Mol Cell Biol. 2006 Nov;7(11):847-59
references.pmid: 16990790
references.citation: Trends Plant Sci. 2009 Apr;14(4):182-8
references.pmid: 19285905
references.citation: Science. 2002 Feb 15;295(5558):1299-301
references.pmid: 11847343
references.citation: Nature. 2005 Jan 6;433(7021):39-44
references.pmid: 15635403
references.citation: Curr Opin Plant Biol. 2005 Feb;8(1):77-85
references.pmid: 15653404
references.citation: Science. 2008 Mar 7;319(5868):1384-6
references.pmid: 18258861
references.citation: Plant Physiol. 2011 Feb;155(2):721-34
references.pmid: 21119044
references.citation: Plant Physiol. 1985 May;78(1):89-91
references.pmid: 16664216
references.citation: Science. 1998 Dec 18;282(5397):2226-30
references.pmid: 9856939
references.citation: Annu Rev Phytopathol. 2010;48:93-117
references.pmid: 20687831
references.citation: Nature. 2005 May 26;435(7041):441-5
references.pmid: 15917797
references.citation: Ann Bot. 2005 Apr;95(5):707-35
references.pmid: 15749753
references.citation: Planta. 2006 Jul;224(2):288-99
references.pmid: 16404575
references.citation: J Exp Bot. 2006;57(6):1341-51
references.pmid: 16531462
references.citation: Plant J. 1999 Apr;18(1):111-9
references.pmid: 10341448
references.citation: Plant Cell. 2005 Aug;17(8):2230-42
references.pmid: 15980261
references.citation: Science. 2008 Nov 28;322(5906):1380-4
references.pmid: 19039136
references.citation: Plant Cell Rep. 2012 May;31(5):801-12
references.pmid: 22315145
references.citation: Cell Mol Life Sci. 1998 Jul;54(7):619-27
references.pmid: 9711229
references.citation: Plant Physiol. 2010 Oct;154(2):487-92
references.pmid: 20921170
references.citation: J Integr Plant Biol. 2008 Sep;50(9):1070-7
references.pmid: 18844775
references.citation: Development. 2011 Mar;138(5):839-48
references.pmid: 21270053
references.citation: Nature. 2008 Nov 27;456(7221):459-63
references.pmid: 19037309
references.citation: Annu Rev Cell Dev Biol. 2008;24:55-80
references.pmid: 18631113
references.citation: Phytochemistry. 2012 Dec;84:18-23
references.pmid: 22989740
references.citation: Plant Cell. 2009 Mar;21(3):736-48
references.pmid: 19258439
references.citation: Annu Rev Plant Biol. 2007;58:93-113
references.pmid: 17177637