title: Effects of infusion of different fluids during controlled hypotension on gastric intramucosal pH and postoperative gastroenterological function.
abstract: The present study was aimed to investigate the effects of infusion of different fluids combined with controlled hypotension on gastric intramucosal pH (pHi) and postoperative gastrointestinal function in patients undergoing hepatocarcinoma surgery. Forty-five patients (ASA II) scheduled for surgical resection of hepatocarcinoma undergoing controlled hypotension were randomly assigned to three groups and received infusion of 20 mL/kg Ringer's solution (R group), 6% HAES(H group) or 6% Voluven group (W group). Intragastric PgCO2, pHi, hematocrit and hemoglobin were measured. The significant decrease of pHi and increase of PgCO2 were produced at 1 and 2 h after controlled hypotension in the R group (P < 0.05 or P < 0.01). The time of bowel movement after operation was shorter in the W group than the R group. Meanwhile, we also did not find obvious difference in blood gas indexes among the three groups. The infusion of HAES and Voluven during controlled hypotension could improve gastrointestinal perfusion and accelerate the recovery of postoperative gastrointestinal function.
authors.affiliation: Department of Anesthesiology, the Affiliated Hospital of Xuzhou Medical College, Xuzhou, Jiangsu 221002, China.
authors.forename: Guanglei
authors.initials: G
authors.lastname: Wang
authors.forename: Su
authors.initials: S
authors.lastname: Liu
authors.forename: Gongjian
authors.initials: G
authors.lastname: Liu
keywords: controlled hypotension; gastric mucosa; hemodilution
references.citation: Pharmacotherapy. 2010 Oct;30(10):1057-71
references.pmid: 20874043
references.citation: Can J Anaesth. 2003 Dec;50(10):1009-16
references.pmid: 14656778
references.citation: J Alzheimers Dis. 2010;21(2):519-26
references.pmid: 20555135
references.citation: Eur J Cardiothorac Surg. 1993;7(5):231-4
references.pmid: 8517950
references.citation: Crit Care Clin. 1996 Oct;12(4):1007-18
references.pmid: 8902381
references.citation: Crit Care Med. 2004 Jan;32(1):194-200
references.pmid: 14707579
references.citation: Intensive Care Med. 1997 Jul;23(7):738-42
references.pmid: 9290986
references.citation: Anesthesiology. 2009 Mar;110(3):496-504
references.pmid: 19225390
references.citation: Eur J Vasc Endovasc Surg. 2009 Mar;37(3):319-25
references.pmid: 19058981
references.citation: Med Sci Monit. 2002 Jan;8(1):CR28-30
references.pmid: 11782677
references.citation: Br J Anaesth. 2000 Jan;84(1):74-86
references.pmid: 10740551
references.citation: J Trauma. 2009 Feb;66(2):337-45
references.pmid: 19204505
references.citation: Crit Care. 2009;13(4):R113
references.pmid: 19591694
references.citation: Masui. 2009 Feb;58(2):174-7
references.pmid: 19227170
references.citation: Anesth Analg. 2001 Nov;93(5):1116-20
references.pmid: 11682378
references.citation: J Biol Chem. 1995 Sep 15;270(37):21707-14
references.pmid: 7665588
references.citation: J Crit Care. 1998 Jun;13(2):49-54
references.pmid: 9627270
references.citation: Anesthesiology. 2003 Mar;98(3):658-69
references.pmid: 12606910
references.citation: Anesth Analg. 2001 Apr;92(4):855-62
references.pmid: 11273914
references.citation: Anesthesiology. 2001 Nov;95(5):1182-8
references.pmid: 11684988
references.citation: J Clin Anesth. 2000 Sep;12(6):421-6
references.pmid: 11090726
references.citation: Crit Care Med. 2000 May;28(5):1585-9
references.pmid: 10834716
references.citation: Eur J Anaesthesiol. 1999 Aug;16(8):519-25
references.pmid: 10500940
references.citation: J Trauma. 2003 May;54(5):848-59; discussion 859-61
references.pmid: 12777898
references.citation: Acta Anaesthesiol Scand. 2000 Oct;44(9):1116-21
references.pmid: 11028733
references.citation: Can J Anaesth. 1995 Nov;42(11):1035-9
references.pmid: 8590494
references.citation: Anesth Analg. 1999 Dec;89(6):1371-7
references.pmid: 10589610
references.citation: Shock. 1996 Jul;6(1):61-5
references.pmid: 8828087
references.citation: Wiad Lek. 2005;58(11-12):652-9
references.pmid: 16594477
references.citation: Eur J Anaesthesiol. 2009 Feb;26(2):160-5
references.pmid: 19142092
references.citation: Stroke. 1995 Sep;26(9):1620-6
references.pmid: 7660409