title: Histopathologic Characteristics of a Coronary-pulmonary Artery Fistula with a Coronary Artery Aneurysm.
abstract: Here, we report a case of a 59-year-old woman with a coronary-pulmonary artery fistula with a concomitant coronary artery aneurysm, which comprised an anomalous coronary artery originating at the right coronary cusp, an aberrant branch of the left anterior descending artery, and a coronary artery aneurysm draining into the main pulmonary artery. Histopathologically, non-dilated anomalous coronary artery showed the preservation of internal elastic lamina and medial smooth muscle cell phenotype which lacked in the aneurysmal wall. Thus, the disrupted internal elastic lamina and phenotypic change of medial smooth muscle cells might contribute to aneurysm formation in a coronary-pulmonary arterial fistula.
authors.affiliation: Department of Pathology, Faculty of Medicine, Fukuoka University, Fukuoka, Fukuoka, Japan.
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Sakata
authors.forename: Noritoshi
authors.initials: N
authors.lastname: Minematsu
authors.forename: Noritsugu
authors.initials: N
authors.lastname: Morishige
authors.forename: Tadashi
authors.initials: T
authors.lastname: Tashiro
authors.forename: Yoshinobu
authors.initials: Y
authors.lastname: Imanaga
keywords: coronary artery aneurysm; coronary-pulmonary artery fistula; histology; immunohistochemistry
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