title: Side effects of perioperative intravesical treatment and treatment strategies for these side effects.
abstract: Perioperative intravesical chemotherapy has a well-established role in the treatment of non-muscle invasive bladder cancer. There are multiple agents that can be used in this fashion with varying properties. Although chemical cystitis is the most common side effect and is usually self-limiting, significant toxicity can occur with intravesical chemotherapy. It is imperative that the urologist is aware of the acute and delayed side effects of intravesical chemotherapy and how to manage potential complications. Both local and systemic toxicities are discussed, as well as strategies to minimize and manage them.
authors.affiliation: Department of Urology, University of Kansas Medical Center, Kansas City, KS 66160, USA. jgriffin3@kumc.edu
authors.forename: Joshua G
authors.initials: JG
authors.lastname: Griffin
authors.forename: Jeff
authors.initials: J
authors.lastname: Holzbeierlein
mesh_terms: D000283:Administration, Intravesical; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D003131:Combined Modality Therapy; D064420:Drug-Related Side Effects and Adverse Reactions / Q000139:chemically induced / Q000628:therapy; D006801:Humans; D019990:Perioperative Care; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy* / Q000601:surgery
chemical_list: D000970:Antineoplastic Agents