title: Making biological theory more down to Earth.
abstract: All of the basic functional components of living organisms participating in describing, translating and constructing themselves are described deep within the supporting dynamics itself. A most common material vehicle for implementing this type of self-organization is a material vehicle holding its own identity through the constant exchange of the constituent material elements. The exchange of materials serves as a material means for temporarily ameliorating the infliction of vicious circles being inevitable and latent in the self-referential complications when descriptively approached in the present tense alone, thus dissolving the difficulties in making their predication logically transparent on material terms. Since the exchange of materials is demonstrable experimentally as in the running of the citric acid cycle in the absence of biological enzymes under the conditions simulating the prebiotic environments in the vicinity of hydrothermal vents on the primitive ocean floor, the prior emergence of metabolism could make the subsequent emergence of metabolism-replication complex more likely compared to the cases otherwise. An essence of the occurrence of the material vehicle holding its identity through the exchange of reacting molecules with the new ones recruited from the outside is in the soundness of internalizing the description of the dynamics into the dynamics itself, which is approachable through the constant update of the present perfect tense in the present progressive tense.
authors.affiliation: Nagaoka University of Technology, Nagaoka 940-2188, Japan. Electronic address: CXQ02365@nifty.com.
authors.forename: Koichiro
authors.initials: K
authors.lastname: Matsuno
mesh_terms: D000465:Algorithms; D000818:Animals; D001703:Biophysics / Q000379:methods*; D002952:Citric Acid Cycle / Q000502:physiology*; D003198:Computer Simulation; D004734:Energy Metabolism / Q000502:physiology*; D006801:Humans; D008433:Mathematics; D008954:Models, Biological; D008967:Molecular Biology / Q000379:methods*; D049490:Systems Biology / Q000379:methods*; D018511:Systems Integration
keywords: Citric acid cycle; Description; Exchange of materials; Metabolism; Relative state; Self reference