title: Serum vitamin D levels in children with recurrent otitis media.
abstract: The aims of this study were to evaluate serum vitamin D levels in cases of recurrent otitis media and investigate the effect of vitamin D therapy on the risk of re-occurrence of the disease. This prospective study was performed by comparing serum vitamin D levels in children with recurrent otitis media and healthy children. Eighty-four children between 1 and 5 years of age and diagnosed with recurrent otitis media were enrolled as the study group. One hundred-and-eight healthy children with similar demographic characteristics were enrolled as the control group. Patients were divided into groups according to their serum 25(OH) vitamin D levels. In patients with low initial serum vitamin D levels, vitamin D therapy was administered in addition to conventional treatment for otitis media. Mean serum 25(OH) vitamin D level in the study group was 11.4 ± 9.8 ng/mL Serum 25(OH) vitamin D levels were below 20 ng/mL in 69 % (n = 58) of cases in this group. In the control group, mean serum 25(OH) vitamin D level was 29.2 ± 13.9 ng/mL and was below 20 ng/mL in 30 % (n = 32) of cases. Comparison of serum 25(OH) vitamin D levels and PTH in the study and control groups revealed a statistically significant difference (p < 0.05). Treatment was initiated in cases diagnosed with vitamin D deficiency, and patients were followed up in due course. The only episodes detected over the course of 1-year follow-up were one attack in five patients and two attacks in two. We believe that co-administration of supplementary vitamin D together with conventional treatments is appropriate in the management of upper respiratory infections such as otitis media.
authors.affiliation: Department of Pediatric Endocrinology, Faculty of Medicine, Ataturk University, Erzurum, Turkey, dratillacayir@gmail.com.
authors.forename: Atilla
authors.initials: A
authors.lastname: Cayir
authors.forename: Mehmet Ibrahim
authors.initials: MI
authors.lastname: Turan
authors.forename: Ozalkan
authors.initials: O
authors.lastname: Ozkan
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Cayir
authors.forename: Avni
authors.initials: A
authors.lastname: Kaya
authors.forename: Salih
authors.initials: S
authors.lastname: Davutoglu
authors.forename: Behzat
authors.initials: B
authors.lastname: Ozkan
mesh_terms: D002112:Calcifediol / Q000097:blood*; D016022:Case-Control Studies; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D010033:Otitis Media / Q000097:blood* / Q000150:complications; D010281:Parathyroid Hormone / Q000097:blood*; D011446:Prospective Studies; D012008:Recurrence; D014808:Vitamin D Deficiency / Q000097:blood* / Q000150:complications
chemical_list: D010281:Parathyroid Hormone; D002112:Calcifediol
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