title: Comparison of the therapeutic effectiveness of sustained low-efficiency dialysis (SLED) with continuous blood purification (CBP) in critically ill patients.
abstract: The differences in therapeutic effectiveness between sustained low-efficiency dialysis (SLED) and continuous blood purification (CBP) were investigated. In order to assess the different treatment methods, 56 critically ill patients were divided into two groups, the CBP group and the SLED group. A comparison was made between all the biochemical indicators, in-hospital duration, hemodynamic parameters, acute physiology and chronic health evaluation (APACHE-II), the survival, and the mortality rates. After treatment, the levels of serum creatine kinase isozyme MB (CK-MB), creatine kinase, creatinine, glutamate-oxalacetate transaminase (AST), glutamate-pyruvate transaminase (ALT), APACHE II score on the 1st, 2nd, and 7th day in both the treatment groups were lower than that before the treatment (P < 0.05). There are no statistical differences in in-hospital duration, biochemical indicators, APACHE II score, hemodynamic parameters, the survival rate and the mortality rate between the two groups (P > 0.05). It was concluded that SLED has similar hemodynamic stability with CBP and the two methods have similar treatment effects in critically ill patients. However, we noticed that SLED can be relatively economical and convenient for critically ill patients in clinical practice.
authors.affiliation: Department of Nephrology, The First Hospital of JingZhou, Yangtze University, Hangkongstreet 8, Jingzhou, 434000, Hubei, China, cjz709@126.com.
authors.forename: Junzhang
authors.initials: J
authors.lastname: Cheng
authors.forename: Shouliang
authors.initials: S
authors.lastname: Hu
authors.forename: Hongzhu
authors.initials: H
authors.lastname: Lu
authors.forename: Qingfeng
authors.initials: Q
authors.lastname: Lei
authors.forename: Juncheng
authors.initials: J
authors.lastname: Liu
authors.forename: Fanli
authors.initials: F
authors.lastname: Yuan
authors.forename: Rong
authors.initials: R
authors.lastname: Chen
mesh_terms: D018806:APACHE; D000328:Adult; D000367:Age Factors; D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D003402:Creatine Kinase / Q000097:blood; D052279:Creatine Kinase, MB Form / Q000097:blood; D003404:Creatinine / Q000097:blood; D016638:Critical Illness / Q000401:mortality / Q000628:therapy*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000379:methods* / Q000592:standards; D012737:Sex Factors; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D003404:Creatinine; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D003402:Creatine Kinase; D052279:Creatine Kinase, MB Form