title: A young woman with HIV and hemiparesis.
abstract: Progressive Multifocal Leucoencephalopathy (PML) is a rare and invariably fatal neurological disease that is seen patients with untreated HIV infection and as a complication of immune suppression with agents such as natalizumab. With the increasing occurrence of HIV, it is important to consider this condition in the differential diagnosis of patients with neurological features. We present the case of a young woman with a long history of HIV infection who presented with neurological symptoms; recognition of this diagnosis enabled identification of her poor compliance with treatment. The investigation and treatment of this condition is discussed.
authors.affiliation: Milton Keynes Hospital NHS Foundation Trust Standing Way, Eaglestone Milton Keynes MK6 5LD. nsvarunkumar@yahoo.co.in
authors.forename: Varun
authors.initials: V
authors.lastname: Nelatur
authors.forename: Bill
authors.initials: B
authors.lastname: Smith
authors.forename: Dushyant
authors.initials: D
authors.lastname: Mital
authors.forename: Mehul
authors.initials: M
authors.lastname: Parekh
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use; D023241:Antiretroviral Therapy, Highly Active; D001921:Brain / Q000473:pathology; D004279:DNA, Viral / Q000134:cerebrospinal fluid; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007577:JC Virus / Q000302:isolation & purification; D007968:Leukoencephalopathy, Progressive Multifocal / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D008279:Magnetic Resonance Imaging; D055118:Medication Adherence; D000069442:Natalizumab; D010291:Paresis / Q000209:etiology; D011379:Prognosis; D055815:Young Adult
chemical_list: D019380:Anti-HIV Agents; D061067:Antibodies, Monoclonal, Humanized; D004279:DNA, Viral; D000069442:Natalizumab