title: Fabrication of hand-in-hand nanostructure for one-step protein detection.
abstract: A new strategy to fabricate an aptamer-protein nanowire at an electrode surface is reported in this paper, and a simple electrochemical method to determine the concentration of a protein is proposed with high sensitivity and selectivity.
authors.affiliation: Department of Biochemistry and State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, PR China.
authors.forename: Chao
authors.initials: C
authors.lastname: Li
authors.forename: Zhaoyin
authors.initials: Z
authors.lastname: Wang
authors.forename: Tao
authors.initials: T
authors.lastname: Gao
authors.forename: Aiping
authors.initials: A
authors.lastname: Duan
authors.forename: Genxi
authors.initials: G
authors.lastname: Li
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry; D056831:Coordination Complexes / Q000737:chemistry; D015342:DNA Probes / Q000737:chemistry / Q000378:metabolism; D055664:Electrochemical Techniques; D004566:Electrodes; D006046:Gold / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry*; D053770:Nanowires / Q000737:chemistry; D010084:Oxidation-Reduction; D011506:Proteins / Q000032:analysis* / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry; D013438:Sulfhydryl Compounds / Q000737:chemistry
chemical_list: D052157:Aptamers, Nucleotide; D056831:Coordination Complexes; D015342:DNA Probes; D011506:Proteins; D013438:Sulfhydryl Compounds; D006046:Gold; D012428:Ruthenium