title: Pyothorax-associated lymphoma: complete remission achieved by chemotherapy alone.
abstract: We present the case of a patient with malignant lymphoma resulting from chronic pyothorax after artificial pneumothorax for pulmonary tuberculosis. The 81-year-old female patient had a medical history of artificial pneumothorax from left pulmonary tuberculosis when she was 23 years old and subsequent chronic pyothorax. She had become aware of pain in the left back from October 2008. Chest computed tomography revealed a tumor measuring 61 mm × 27 mm behind the left sixth and seventh ribs. After biopsy revealed pyothorax-associated lymphoma, 4 courses of R-CHOP therapy were administered, leading to complete remission. No recurrences were noted during follow-up over a 4-year period after the initiation of therapy.
authors.affiliation: Department of General Thoracic Surgery, Tokai University Tokyo Hospital, Tokyo, Japan, k167999@is.icc.u-tokai.ac.jp.
authors.forename: Tomoki
authors.initials: T
authors.lastname: Nakagawa
authors.forename: Takayuki
authors.initials: T
authors.lastname: Nakano
authors.forename: Ryota
authors.initials: R
authors.lastname: Masuda
authors.forename: Masayuki
authors.initials: M
authors.lastname: Iwazaki
authors.forename: Ichiro
authors.initials: I
authors.lastname: Kuwahira
authors.forename: Naoya
authors.initials: N
authors.lastname: Nakamura
authors.forename: Kenji
authors.initials: K
authors.lastname: Nakano
mesh_terms: D000369:Aged, 80 and over; D058846:Antibodies, Monoclonal, Murine-Derived / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D016724:Empyema, Pleural / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000188:drug therapy / Q000209:etiology*; D009364:Neoplasm Recurrence, Local; D011031:Pneumothorax, Artificial / Q000009:adverse effects*; D011241:Prednisone / Q000627:therapeutic use; D000069283:Rituximab; D013899:Thoracic Neoplasms / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014397:Tuberculosis, Pulmonary / Q000601:surgery*; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D058846:Antibodies, Monoclonal, Murine-Derived; C571759:R-CHOP protocol; D000069283:Rituximab; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone
references.citation: Kyobu Geka. 1991 Aug;44(9):739-42
references.pmid: 1956133
references.citation: Nihon Kokyuki Gakkai Zasshi. 2010 Mar;48(3):186-91
references.pmid: 20387521
references.citation: Jpn J Clin Oncol. 1989 Sep;19(3):249-57
references.pmid: 2681886