title: First case of pulmonary disease caused by a Mycobacterium avium complex strain of presumed veterinary origin in an adult human patient.
abstract: We report the first case of pulmonary disease caused by a strain of Mycobacterium avium complex of presumed veterinary origin in an elderly patient. All serial isolates were identified by multilocus sequence analysis based on rpoB, hsp65, and 16S rRNA fragments. Disease persisted despite macrolide-based combination antibiotic therapy.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Medicine, Sungkyunkwan University School of Medicine, Seoul, South Korea.
authors.forename: Su-Young
authors.initials: SY
authors.lastname: Kim
authors.forename: Sung Jae
authors.initials: SJ
authors.lastname: Shin
authors.forename: Nam Yong
authors.initials: NY
authors.lastname: Lee
authors.forename: Won-Jung
authors.initials: WJ
authors.lastname: Koh
mesh_terms: D000368:Aged; D000818:Animals; D000995:Antitubercular Agents / Q000627:therapeutic use; D001426:Bacterial Proteins; D018834:Chaperonin 60; D016000:Cluster Analysis; D004269:DNA, Bacterial / Q000737:chemistry / Q000235:genetics; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D012321:DNA-Directed RNA Polymerases; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D015269:Mycobacterium avium Complex / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D013902:Radiography, Thoracic; D017422:Sequence Analysis, DNA; D014057:Tomography, X-Ray Computed; D017211:Treatment Failure; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D015047:Zoonoses / Q000382:microbiology* / Q000635:transmission
chemical_list: D000995:Antitubercular Agents; D001426:Bacterial Proteins; D018834:Chaperonin 60; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S; C074119:heat-shock protein 65, Mycobacterium; D012321:DNA-Directed RNA Polymerases; C105078:RNA polymerase beta subunit
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