title: Allosteric activation of PI3Kα by oncogenic mutations.
authors.forename: John E
authors.initials: JE
authors.lastname: Burke
authors.forename: Olga
authors.initials: O
authors.lastname: Perisic
authors.forename: Roger L
authors.initials: RL
authors.lastname: Williams
mesh_terms: D000494:Allosteric Regulation; D058543:Class Ia Phosphatidylinositol 3-Kinase / Q000235:genetics* / Q000378:metabolism*; D006801:Humans; D008958:Models, Molecular; D009154:Mutation; D009369:Neoplasms / Q000201:enzymology* / Q000235:genetics*; D009857:Oncogenes; D011487:Protein Conformation
chemical_list: D058543:Class Ia Phosphatidylinositol 3-Kinase
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