title: The impact of cognitive behavioral therapy on IL-6 levels in unmedicated women experiencing the first episode of depression: a pilot study.
abstract: A group of 11 women (18-29 years old) in the first episode of depression was evaluated before and after cognitive behavioral therapy (CBT). Depressive scores, assessed by Hamilton Rating Scale (HRSD), and serum IL-6 levels significantly decreased after the seventh session. These results suggest that CBT reduced both depressive symptoms and the inflammatory state in women.
authors.affiliation: Universidade Católica de Pelotas (UCPel), Department of Life and Health Sciences, Pelotas, Rio Grande do Sul, Brazil.
authors.forename: Marta
authors.initials: M
authors.lastname: Gazal
authors.forename: Luciano D
authors.initials: LD
authors.lastname: Souza
authors.forename: Briane A
authors.initials: BA
authors.lastname: Fucolo
authors.forename: Carolina D
authors.initials: CD
authors.lastname: Wiener
authors.forename: Ricardo A
authors.initials: RA
authors.lastname: Silva
authors.forename: Ricardo T
authors.initials: RT
authors.lastname: Pinheiro
authors.forename: Karen
authors.initials: K
authors.lastname: Jansen
authors.forename: Gabriele
authors.initials: G
authors.lastname: Ghislene
authors.forename: Jean P
authors.initials: JP
authors.lastname: Oses
authors.forename: Manuella P
authors.initials: MP
authors.lastname: Kaster
mesh_terms: D000293:Adolescent; D000328:Adult; D000470:Alkaloids; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003863:Depression / Q000097:blood* / Q000534:rehabilitation*; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D010865:Pilot Projects; D011569:Psychiatric Status Rating Scales; D012044:Regression Analysis; D055815:Young Adult
chemical_list: D000470:Alkaloids; D015850:Interleukin-6; C110131:Wilcox compound
keywords: Cognitive behavioral therapy; Depression; Interleukin-6