title: General synthetic approach to functionalized dihydrooxepines.
abstract: A three-step sequence to access functionalized 4,5-dihydrooxepines from cyclohexenones has been developed. This approach features a regioselective Baeyer-Villiger oxidation and subsequent functionalization via the corresponding enol phosphate intermediate.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States. kcn@scripps.edu
authors.forename: K C
authors.initials: KC
authors.lastname: Nicolaou
authors.forename: Ruocheng
authors.initials: R
authors.lastname: Yu
authors.forename: Lei
authors.initials: L
authors.lastname: Shi
authors.forename: Quan
authors.initials: Q
authors.lastname: Cai
authors.forename: Min
authors.initials: M
authors.lastname: Lu
authors.forename: Philipp
authors.initials: P
authors.lastname: Heretsch
mesh_terms: D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D003512:Cyclohexanones / Q000737:chemistry*; D015394:Molecular Structure; D010082:Oxepins / Q000138:chemical synthesis* / Q000737:chemistry; D010084:Oxidation-Reduction; D013237:Stereoisomerism
chemical_list: D003512:Cyclohexanones; D010082:Oxepins
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