title: TIPS-TTF as a precursor of low-symmetry TTF derivatives: steric protection strategy in the regioselective C-H modification of TTF.
abstract: Triisopropylsilyltetrathiafulvalene (TIPS-TTF) has been devised as a promising platform for the synthesis of low-symmetry TTF derivatives. The bulky TIPS group allows TIPS-TTF to undergo palladium-catalyzed direct diarylation as well as LDA-mediated dilithiation exclusively on the roomier dithiole ring. Subsequent fluoride-mediated protodesilylation provided vicinally difunctionalized TTF, which could undergo further functionalization.
authors.affiliation: Department of Chemistry, Graduate School of Science, Kyoto University, Kyoto 606-8502, Japan.
authors.forename: Ryota
authors.initials: R
authors.lastname: Ueno
authors.forename: Daishi
authors.initials: D
authors.lastname: Fujino
authors.forename: Hideki
authors.initials: H
authors.lastname: Yorimitsu
authors.forename: Atsuhiro
authors.initials: A
authors.lastname: Osuka