title: Impact of the aspirated volume of fat tissue in the insulin resistance after liposuction.
abstract: OBJECTIVE
  To investigate insulin resistance imposed by liposuction, correlating its intensity with the extent of the operation.
  
  
  METHODS
  The sample consisted of 20 female patients without comorbidities, aged between 21 and 43 years, body mass index between 19 and 27 kg/m², undergoing liposuction alone or associated with breasts' prosthesis. We assessed insulin resistance at the beginning and end of the procedure by calculating the Homeostasis Model Assessment (HOMA-IR). The operative variables were length of liposuction, breast prosthesis time, body areas submitted to liposuction and total fat aspirated.
  
  
  RESULTS
  The liposuction time was 94-278 min (mean = 174 min), duration of breast prosthesis 20-140 min (mean = 65 min) and total fat aspirated 680-4280 g (mean = 1778 g). Statistical analysis was performed by considering a division line of 1500 g of aspirated fat and there was a significantly increased insulin resistance by HOMA index greater in the group > 1500 g (123% increase) than in the group d" 1500 g (an increase of 53 %) from the baseline data (p = 0.02). Other operative variables showed no significant correlation.
  
  
  CONCLUSIONS
  Insulin resistance shows significant increase in liposuction, and it is correlated to the volume of aspirated fat.
authors.affiliation: Faculty of Medicine, Federal University of Mato Grosso, Cuiabá, State of Mato Grosso - MT, Brazil.
authors.forename: Sérgio de Souza
authors.initials: Sde S
authors.lastname: Oliveira
authors.forename: Jubert Sanches
authors.initials: JS
authors.lastname: Cibantos
authors.forename: Wagner Targa
authors.initials: WT
authors.lastname: Ripari
authors.forename: José Eduardo de
authors.initials: JE
authors.lastname: Aguilar-Nascimento
mesh_terms: D000273:Adipose Tissue; D000328:Adult; D005260:Female; D006801:Humans; D007333:Insulin Resistance; D015187:Lipectomy; D011446:Prospective Studies; D055815:Young Adult