title: A multicenter study for a single, three-step laser treatment for cellulite using a 1440-nm Nd:YAG laser, a novel side-firing fiber, and a temperature-sensing cannula.
abstract: BACKGROUND
  Historically, treatments for cellulite have not been able to address all of its physiological components and require multiple sessions.
  
  
  OBJECTIVE
  The authors evaluate the safety and efficacy of a single, subdermal procedure to treat the underlying structure of cellulite.
  
  
  METHODS
  Fifty-seven patients underwent a 3-step cellulite treatment with a 1440-nm Nd:YAG laser with a side-firing fiber and temperature-sensing cannula. Efficacy was measured by the ability of blinded evaluators to distinguish baseline photos from those taken at 3 and 6 months posttreatment, as well as their rating of the results on a 5-point, 2-category ordinal photonumeric scale when comparing baseline photos to those taken at 2, 3, and 6 months posttreatment. Patient and physician satisfaction was assessed based on completion of a satisfaction survey at 2, 3, and 6 months posttreatment. Adverse events (AE) were recorded throughout the study.
  
  
  RESULTS
  At 6 months posttreatment, blinded evaluators rated at least a 1-point improvement in the appearance of cellulite in 96% of treated sites. Blinded evaluators were also able to correctly identify baseline versus posttreatment photos in 95% of cases. At least 90% of patients and physicians reported satisfaction with the results of treatment throughout 6 months. AE were mild in intensity and transient to treatment.
  
  
  CONCLUSIONS
  A single, 3-step, minimally invasive laser treatment using a 1440-nm Nd:YAG laser, side-firing fiber, and temperature-sensing cannula to treat the underlying structure of cellulite proved to be safe and maintained effectiveness at least 6 months posttreatment.
  
  
  METHODS
  2.
authors.affiliation: University of Medicine and Dentistry of New Jersey, Montclair, New Jersey 07042, USA.
authors.forename: Barry
authors.initials: B
authors.lastname: DiBernardo
authors.forename: Gordon
authors.initials: G
authors.lastname: Sasaki
authors.forename: Bruce E
authors.initials: BE
authors.lastname: Katz
authors.forename: Joseph P
authors.initials: JP
authors.lastname: Hunstad
authors.forename: Christine
authors.initials: C
authors.lastname: Petti
authors.forename: A Jay
authors.initials: AJ
authors.lastname: Burns
mesh_terms: D000273:Adipose Tissue / Q000503:physiopathology / Q000528:radiation effects*; D000328:Adult; D002081:Buttocks / Q000503:physiopathology / Q000528:radiation effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000379:methods*; D008875:Middle Aged; D009765:Obesity / Q000503:physiopathology / Q000532:radiotherapy*; D017060:Patient Satisfaction / Q000706:statistics & numerical data; D011446:Prospective Studies; D018570:Risk Assessment; D050151:Subcutaneous Fat / Q000528:radiation effects; D013697:Thermosensing; D013848:Thigh / Q000503:physiopathology / Q000528:radiation effects; D016896:Treatment Outcome; D055815:Young Adult
keywords: Nd: YAG laser; cellulite; cellulite laser treatment; cosmetic medicine; minimally invasive treatment