title: Correlation between microdilution, Etest, and disk diffusion methods for antifungal susceptibility testing of fluconazole against Candida sp. blood isolates.
abstract: BACKGROUND
  Antifungal susceptibility testing assists in finding the appropriate treatment for fungal infections, which are increasingly common. However, such testing is not very widespread. There are several existing methods, and the correlation between such methods was evaluated in this study.
  
  
  METHODS
  The susceptibility to fluconazole of 35 strains of Candida sp. isolated from blood cultures was evaluated by the following methods: microdilution, Etest, and disk diffusion.
  
  
  RESULTS
  The correlation between the methods was around 90%.
  
  
  CONCLUSIONS
  The disk diffusion test exhibited a good correlation and can be used in laboratory routines to detect strains of Candida sp. that are resistant to fluconazole.
authors.affiliation: Laboratório de Pesquisa em Microbiologia de Leveduras, Departamento de Análises Clínicas e Toxicológicas, Faculdade de Farmácia, Universidade Federaldo Ceará, Fortaleza, CE, Brasil.
authors.forename: Everardo Albuquerque
authors.initials: EA
authors.lastname: Menezes
authors.forename: Antônio Alexandre de
authors.initials: AA
authors.lastname: Vasconcelos Júnior
authors.forename: Maria Rozzelê Ferreira
authors.initials: MR
authors.lastname: Ângelo
authors.forename: Maria da Conceição dos Santos Oliveira
authors.initials: Mda C
authors.lastname: Cunha
authors.forename: Francisco Afrânio
authors.initials: FA
authors.lastname: Cunha
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D015725:Fluconazole / Q000494:pharmacology*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods*
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole