title: Mechanical Properties and Tensile Failure Analysis of Novel Bio-absorbable Mg-Zn-Cu and Mg-Zn-Se Alloys for Endovascular Applications.
abstract: In this paper, the mechanical properties and tensile failure mechanism of two novel bio-absorbable as-cast Mg-Zn-Se and Mg-Zn-Cu alloys for endovascular medical applications are characterized. Alloys were manufactured using an ARC melting process and tested as-cast with compositions of Mg-Zn-Se and Mg-Zn-Cu, being 98/1/1 wt.% respectively. Nanoindentation testing conducted at room temperature was used to characterize the elastic modulus (E) and surface hardness (H) for both the bare alloys and the air formed oxide layer. As compared to currently available shape memory alloys and degradable as-cast alloys, these experimental alloys possess superior as-cast mechanical properties that can increase their biocompatibility, degradation kinetics, and the potential for medical device creation.
authors.affiliation: Department of Biomedical Engineering, Florida International University, Miami, FL 33199, USA.
authors.forename: Dharam
authors.initials: D
authors.lastname: Persaud-Sharma
authors.forename: Noah
authors.initials: N
authors.lastname: Budiansky
authors.forename: Anthony J
authors.initials: AJ
authors.lastname: McGoron
keywords: Mg-Zn-Cu; Mg-Zn-Se; fracture analysis; magnesium alloys; mechanical properties
references.citation: Heart. 2001 Nov;86(5):563-9
references.pmid: 11602554
references.citation: Catheter Cardiovasc Interv. 2005 Dec;66(4):595-6
references.pmid: 16284981
references.citation: Trends Biomater Artif Organs. 2012;26(2):74-85
references.pmid: 22754200
references.citation: Circulation. 2000 Jul 25;102(4):371-3
references.pmid: 10908206
references.citation: J Biomim Biomater Tissue Eng. 2012 Feb 3;12:25-39
references.pmid: 22408600
references.citation: Cardiovasc Intervent Radiol. 2006 Jan-Feb;29(1):11-6
references.pmid: 16195840
references.citation: Int J Mol Sci. 2011;12(7):4250-70
references.pmid: 21845076