title: [A cross-sectional study to assess cardiovascular risk in the children of parents with diabetes mellitus or arterial hypertension].
abstract: BACKGROUND
  Cardiovascular disease in adults is the first cause of death, and in adolescents under 15 years old, it is the third cause of death. The purpose of this study was to investigate which risk factors for cardiovascular disease have the children of parents with diabetes or hypertension.
  
  
  METHODS
  In a cross-sectional study conducted in the Family Medicine Unit No. 80 in Morelia, Michoacán, Mexico, were included 156 patients with diabetes mellitus, hypertension and without diabetes or hypertension (10 years of disease progression), and a biological child (age 7-15 years) to form pairs. Three groups were formed: child-parent with Diabetes; child-parent with Hypertension and child-parent without Diabetes or Hypertension. Medical history, body mass index, blood glucose, cholesterol, triglycerides, c-LDL, c-HDL and signs of metabolic syndrome were recorded.
  
  
  RESULTS
  The frequency of signs of metabolic syndrome was higher in parents with Diabetes (28.8%), and in children of parents without either diabetes or hypertension (11.5%). In binomial children-parents with Diabetes, serum glucose (OR=4.50: 95% CI; 2.32-8.73, P<.0001) was the most important risk factor to develop cardiovascular disease; in binomial children-parents with Hypertension it was total cholesterol (OR=4.143: 95% CI; 1.996-8.60, P<.0001); and, in binomial children-parents without either Diabetes or Hypertension, the abdominal circumference (OR=3.429: 95% CI; 1.621-7.251, P<.0001) was the most important risk factor.
  
  
  CONCLUSIONS
  We conclude that children of parents with or without diabetes mellitus or hypertension are at increased risk for developing cardiovascular disease. Longitudinal studies are required using non-pharmacological and pharmacological strategies that will have an impact on the most important risk factors for preventing cardiovascular disease.
authors.affiliation: Instituto Mexicano del Seguro Social, Morelia, Michoacán, México. anel_gomez04@yahoo.com.mx
authors.forename: A
authors.initials: A
authors.lastname: Gómez-García
authors.forename: L
authors.initials: L
authors.lastname: Rangel-García
authors.forename: C
authors.initials: C
authors.lastname: Alvarez-Aguilar
mesh_terms: D000293:Adolescent; D000328:Adult; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D002648:Child; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus; D005260:Female; D006801:Humans; D006973:Hypertension; D008297:Male; D008875:Middle Aged; D010290:Parents; D018570:Risk Assessment