title: Serotype and surface protein gene distribution of colonizing group B streptococcus in women in Egypt.
abstract: Group B streptococcus (GBS) is a leading cause of neonatal sepsis and meningitis. We determined the distribution of serotypes and surface protein encoding genes of GBS strains from pregnant and non-pregnant women in Egypt. Vaginal swabs from 364 women were screened by culture and 100 (27.4%) yielded GBS. Serotype V was the most predominant (33%), followed by serotypes II (17%), III (15%), Ia (14%), VI (12%), Ib (8%) and IV (1%). The most common surface protein genes were epsilon (27%), alp3 (26%), bca (18%), rib (16%) and alp2 (10%). Two isolates were negative for surface protein genes. The distribution of serotypes and surface proteins was similar to reports from other parts of the world but the relatively high frequency of serotype VI was a notable feature of the strains from women in Egypt.
authors.affiliation: Microbiology and Immunology Department, Faculty of Pharmacy, Suez Canal University, Egypt.
authors.forename: S
authors.initials: S
authors.lastname: Shabayek
authors.forename: S
authors.initials: S
authors.lastname: Abdalla
authors.forename: A Mh
authors.initials: AM
authors.lastname: Abouzeid
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D016009:Chi-Square Distribution; D003430:Cross-Sectional Studies; D004534:Egypt / Q000453:epidemiology; D005260:Female; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics*; D011247:Pregnancy; D012703:Serotyping; D013290:Streptococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D013292:Streptococcus agalactiae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D014621:Vagina / Q000382:microbiology
chemical_list: D001426:Bacterial Proteins; D008565:Membrane Proteins
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