title: [Vitamin D and breast cancer: is there a link?].
abstract: OBJECTIVE
  The aim of this review is to know the relationship between breast cancer and vitamin D, synthesised by skin or brought by food or supplementation.
  
  
  METHODS
  The selected articles were extracted from the Pubmed database between 1998 and 2012. The keywords used were: "25-hydroxyvitamin D", "breast cancer recurrence", "breast cancer risk", "serum levels of vitamin D", "vitamin D intake". A total of 37 articles were selected.
  
  
  RESULTS
  The sun exposure, via the skin vitamin D synthesis, is associated with a decreased risk of breast cancer. This decrease seems also likely for food contributions and an over 400IU per day vitamin D supplementation. An inverse relationship between plasma 25-hydroxyvitamin D (25-OH-D) level and breast cancer risk has been suggested. An increased 25-OH-D level seems associated with a decreased risk of breast cancer recurrence.
  
  
  CONCLUSIONS
  Recommendations concerning a vitamin D supplementation could be established, but should be supported by additional studies.
authors.affiliation: Pôle de gynécologie-obstétrique, hôpital de Hautepierre, hôpitaux universitaires de Strasbourg, avenue Molière, 67200 Strasbourg cedex, France. francois.stoll@gmail.com
authors.forename: F
authors.initials: F
authors.lastname: Stoll
authors.forename: C Y
authors.initials: CY
authors.lastname: Akladios
authors.forename: C
authors.initials: C
authors.lastname: Mathelin
mesh_terms: D000293:Adolescent; D000328:Adult; D001943:Breast Neoplasms / Q000097:blood / Q000517:prevention & control; D004032:Diet; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control; D012307:Risk Factors; D013472:Sunlight; D014807:Vitamin D / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000097:blood; D055815:Young Adult
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D