title: IFAG and childhood rosacea: a possible link?
abstract: Idiopathic facial aseptic granuloma (IFAG) is a disorder that usually occurs during early childhood. Its pathogenesis remains poorly understood. The objective of this study was to investigate possible relationships between IFAG and childhood rosacea. This was a retrospective multicenter study of patients attending four French dermatologic centers diagnosed with IFAG between October 2000 and July 2007. Patients and their parents were asked to come for a follow-up visit or to make an appointment for a telephone interview. Clinical symptoms of childhood rosacea were recorded: flushing, permanent or recurrent erythema; facial telangiectasia; papules and pustules on the face without comedones or microcysts; preferential location of the lesions on the convexity of the face; and ophthalmologic involvement of rosacea (recurrent chalazions, conjunctival hyperemia, keratitis). Thirty-eight patients, 20 girls and 18 boys, were included in the study. The median age at the time of diagnosis of IFAG was 43 months, with a median follow-up of 3.9 years. Sixteen patients (42.1%) had at least two criteria of childhood rosacea, 11 of 32 (34.4%) with a single lesion and 5 of 6 (83.3%) with multiple lesions. Children with IFAG are at risk for childhood rosacea, and follow-up is advised, including periodic ophthalmologic assessment.
authors.affiliation: Pediatric Dermatology Unit, Pellegrin Children's Hospital, Bordeaux, France. sorilla.prey@chu-bordeaux.fr
authors.forename: Sorilla
authors.initials: S
authors.lastname: Prey
authors.forename: Khaled
authors.initials: K
authors.lastname: Ezzedine
authors.forename: Juliette
authors.initials: J
authors.lastname: Mazereeuw-Hautier
authors.forename: Catherine
authors.initials: C
authors.lastname: Eschard
authors.forename: Sébastien
authors.initials: S
authors.lastname: Barbarot
authors.forename: Franck
authors.initials: F
authors.lastname: Boralevi
authors.forename: Alain
authors.initials: A
authors.lastname: Taïeb
authors.forename: Christine
authors.initials: C
authors.lastname: Léaute-Labrèze
mesh_terms: D017043:Chalazion / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003229:Conjunctival Diseases / Q000453:epidemiology; D005148:Facial Dermatoses / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006099:Granuloma / Q000453:epidemiology*; D006801:Humans; D007634:Keratitis / Q000453:epidemiology; D008297:Male; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors; D012393:Rosacea / Q000453:epidemiology*