title: Genomic sequence analysis of a new reassortant infectious bursal disease virus from commercial broiler flocks in Central China.
abstract: We report the complete nucleotide sequence of a reassortant infectious bursal disease (IBD) virus (IBDV) HN isolate from commercial broiler flocks in central China. The genome consisted of 3,232 and 2,652 nucleotides in the coding regions of segments A and B, respectively. Alignment of both nucleotide and deduced amino acid sequences and phylogenetic analysis revealed that the genome segments A and B of HN were derived from the attenuated strain B87 and the VV strain OKYM. This is a new reassortant IBDV strain that has emerged in nature, involving segment A of a cell-culture-adapted attenuated vaccine strain B87.
authors.affiliation: Henan Center for Animal Disease Control and Prevention, Animal Husbandry Bureau of Henan Province, Zhengzhou, 450008, Henan Province, People's Republic of China.
authors.forename: Pei
authors.initials: P
authors.lastname: Cui
authors.forename: Shi-Jie
authors.initials: SJ
authors.lastname: Ma
authors.forename: Yu-Geng
authors.initials: YG
authors.lastname: Zhang
authors.forename: Xin-Sheng
authors.initials: XS
authors.lastname: Li
authors.forename: Xiao-Yun
authors.initials: XY
authors.lastname: Gao
authors.forename: Bao-An
authors.initials: BA
authors.lastname: Cui
authors.forename: Hong-Ying
authors.initials: HY
authors.lastname: Chen
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D018175:Birnaviridae Infections / Q000662:veterinary* / Q000821:virology; D002645:Chickens / Q000821:virology*; D002681:China; D016679:Genome, Viral / Q000235:genetics*; D007243:Infectious bursal disease virus / Q000145:classification / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity; D016366:Open Reading Frames; D010802:Phylogeny; D011201:Poultry Diseases / Q000821:virology*; D012367:RNA, Viral / Q000235:genetics; D016865:Reassortant Viruses / Q000235:genetics*; D017422:Sequence Analysis, DNA; D014613:Vaccines, Attenuated / Q000235:genetics* / Q000276:immunology
chemical_list: D012367:RNA, Viral; D014613:Vaccines, Attenuated