title: Susceptibility weighted imaging in the evaluation of movement disorders.
abstract: Movement disorders are neurodegenerative disorders associated with abnormalities of brain iron deposition. In this presentation, we aim to describe the role of susceptibility weighted imaging (SWI) in the imaging of patients with movement disorders and differentiate between the various disorders. SWI is a high-resolution, fully velocity-encoded gradient-echo magnetic resonance imaging (MRI) sequence that consists of using both magnitude and phase information. We describe briefly the physics behind this sequence and the post-processing techniques used. The anatomy of the midbrain and basal ganglia in normal subjects on SWI is covered. A number of neurodegenerative disorders are associated with abnormal iron deposition, which can be detected due to the susceptibility effects.
authors.affiliation: Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, India.
authors.forename: D R
authors.initials: DR
authors.lastname: Hingwala
authors.forename: C
authors.initials: C
authors.lastname: Kesavadas
authors.forename: B
authors.initials: B
authors.lastname: Thomas
authors.forename: T R
authors.initials: TR
authors.lastname: Kapilamoorthy
mesh_terms: D001479:Basal Ganglia / Q000473:pathology*; D006801:Humans; D007501:Iron / Q000378:metabolism; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008636:Mesencephalon / Q000473:pathology*; D009069:Movement Disorders / Q000175:diagnosis* / Q000473:pathology
chemical_list: D007501:Iron