title: Metabolic hypertension: concept and practice.
abstract: Hypertension is a serious public health problem worldwide. More than 60% of the risk factors for hypertension are associated with metabolic disturbances. Metabolic abnormalities increase the risk for hypertension and cause high blood pressure. Improving metabolic disturbances is beneficial for hypertension treatment. Due to the importance of metabolic abnormalities in the pathogenesis of hypertension, we propose a concept of metabolic hypertension. In this review, we discuss and review the clinical types, pathogenesis, risk evaluation and management of metabolic hypertension. Elucidation of the mechanism of metabolic hypertension should facilitate the design of novel pharmacotherapeutics and dedicated antihypertensive manipulations.
authors.affiliation: Center for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Daping Hospital, Third Military Medical University, Chongqing Institute of Hypertension, Chongqing, China. zhuzm@yahoo.com
authors.forename: Zhiming
authors.initials: Z
authors.lastname: Zhu
authors.forename: Peijian
authors.initials: P
authors.lastname: Wang
authors.forename: Shuangtao
authors.initials: S
authors.lastname: Ma
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology* / Q000378:metabolism*; D008659:Metabolic Diseases / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism*; D012307:Risk Factors
chemical_list: D000959:Antihypertensive Agents
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