title: Novel double [3 + 2 + 1] heteroannulation for forming unprecedented dipyrazolo-fused 2,6-naphthyridines.
abstract: A novel four-component strategy for the efficient synthesis of unprecedented dipyrazolo-fused 2,6-naphthyridines through a double [3 + 2+1] heteroannulation has been described. The bond-forming efficiency, accessibility, and generality of this synthesis make it highly valuable to assemble tetra-heterocyclic scaffolds.
authors.affiliation: School of Chemistry and Chemical Engineering, and Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou, 221116 Jiangsu, PR China.
authors.forename: Wei
authors.initials: W
authors.lastname: Fan
authors.forename: Qin
authors.initials: Q
authors.lastname: Ye
authors.forename: Hai-Wei
authors.initials: HW
authors.lastname: Xu
authors.forename: Bo
authors.initials: B
authors.lastname: Jiang
authors.forename: Shu-Liang
authors.initials: SL
authors.lastname: Wang
authors.forename: Shu-Jiang
authors.initials: SJ
authors.lastname: Tu
mesh_terms: D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D009287:Naphthyridines / Q000138:chemical synthesis* / Q000737:chemistry; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D006571:Heterocyclic Compounds; D009287:Naphthyridines; D011720:Pyrazoles