title: [Infective endocarditis in sub-Saharan african children, cross-sectional study about 19 cases in Ouagadougou at Burkina Faso].
abstract: BACKGROUND
  Infective endocarditis is a transplant of a microorganism on a most often injured endocardium. It is rare in children. This work aimed to determine the frequency of endocarditis of the child, to describe clinical presentation, data from echocardiography, microbiological profile and clinical course.
  
  
  METHODS
  From May 1 2010 to April 30 2011, we consecutively included children received for infective endocarditis in two medical centers in the city of Ouagadougou: Saint-Camille medical center and teaching hospital Yalgado-Ouedraogo. We investigated the functional and general signs and treatment already received. The physical examination looking for an infectious syndrome, pneumonia, heart failure and entrance doors. Blood cultures, blood count, creatinine, blood chemistry, HIV status, electrocardiogram, chest radiography and cardiac Doppler ultrasound were systematic. The diagnosis of the disease was based on Duke criteria.
  
  
  RESULTS
  Nineteen endocarditis in children were reported, that is 1.7% of admissions. The average age was 4.7 ± 2.6 years (extremes: 1 and 14). The sex ratio was 1.7 for girls. The clinical presentation was a common infectious syndrome. Impaired general condition and congestive heart failure were present on admission in six cases, respectively. The front door was dental in nine cases (47.4%), skin in four cases (21%) and ENT in three cases (15.8%). A peripheral vein was implicated in one case. In the two other cases, no front door had been found. HIV serology was positive in four cases. As for the blood cultures, they were positive in 13 cases. The germs found were Streptococcus in 10 cases and staphylococcus in three cases. Echocardiography had revealed vegetations in 18 cases. These vegetations were localized on the mitral in nine cases. Multiple locations were found in four cases. Underlying heart disease was dominated by rheumatic valve disease (68.4%), healthy heart forms were found in two cases. Treatment consisted of antibiotics, antipyretic treatment and that of heart failure as appropriate. The evolution was marked by five deaths (26.3%) in an array of septic shock. Death was more important in congenital heart disease.
  
  
  CONCLUSIONS
  Infective endocarditis of the child is common in our practice. The clinical syndrome is common infectious. Streptococcus and Staphylococcus are the two germs found. The main door is dental. Hence, dental care should be promoted for better prevention of infective endocarditis in our context.
authors.affiliation: Service de cardiologie, CHU Yalgado-Ouedraogo, 03 BP, 7022 Ouagadougou cedex 03, Burkina Faso. Electronic address: drnova@hotmail.fr.
authors.forename: N V
authors.initials: NV
authors.lastname: Yameogo
authors.affiliation: Service de cardiologie, CHU Yalgado-Ouedraogo, 03 BP, 7022 Ouagadougou cedex 03, Burkina Faso.
authors.forename: K J
authors.initials: KJ
authors.lastname: Kologo
authors.affiliation: Service de cardiologie, CHU Yalgado-Ouedraogo, 03 BP, 7022 Ouagadougou cedex 03, Burkina Faso.
authors.forename: A A
authors.initials: AA
authors.lastname: Yameogo
authors.affiliation: Service de cardiologie, CHU Yalgado-Ouedraogo, 03 BP, 7022 Ouagadougou cedex 03, Burkina Faso.
authors.forename: C
authors.initials: C
authors.lastname: Yonaba
authors.affiliation: Service de cardiologie, CHU Yalgado-Ouedraogo, 03 BP, 7022 Ouagadougou cedex 03, Burkina Faso.
authors.forename: G R C
authors.initials: GR
authors.lastname: Millogo
authors.affiliation: Service de cardiologie, CHU Yalgado-Ouedraogo, 03 BP, 7022 Ouagadougou cedex 03, Burkina Faso.
authors.forename: S A
authors.initials: SA
authors.lastname: Kissou
authors.affiliation: Service de cardiologie, CHU Yalgado-Ouedraogo, 03 BP, 7022 Ouagadougou cedex 03, Burkina Faso.
authors.forename: B J Y
authors.initials: BJ
authors.lastname: Toguyeni
authors.affiliation: Service de cardiologie, CHU Yalgado-Ouedraogo, 03 BP, 7022 Ouagadougou cedex 03, Burkina Faso.
authors.forename: A K
authors.initials: AK
authors.lastname: Samadoulougou
authors.affiliation: Service de cardiologie, CHU Yalgado-Ouedraogo, 03 BP, 7022 Ouagadougou cedex 03, Burkina Faso.
authors.forename: S
authors.initials: S
authors.lastname: Pignatelli
authors.affiliation: Service de cardiologie, CHU Yalgado-Ouedraogo, 03 BP, 7022 Ouagadougou cedex 03, Burkina Faso.
authors.forename: J
authors.initials: J
authors.lastname: Simpore
authors.affiliation: Service de cardiologie, CHU Yalgado-Ouedraogo, 03 BP, 7022 Ouagadougou cedex 03, Burkina Faso.
authors.forename: P
authors.initials: P
authors.lastname: Zabsonre
mesh_terms: D000293:Adolescent; D017954:Africa South of the Sahara; D002050:Burkina Faso; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004696:Endocarditis / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male
keywords: Afrique subsaharienne; Burkina Faso; Child; Endocardite infectieuse; Enfant; Infectious endocarditis; Sub-Saharan Africa