title: Synthesis and minisci reactions of organotrifluoroborato building blocks.
abstract: Copper-catalyzed borylation of a variety of organic halides with bis(pinacolato)diboron allows the preparation of diverse potassium organotrifluoroborates. The reactions are mild and general, providing access to a variety of interesting, boron-containing building blocks, including those containing piperidine, pyrrole, azetidine, tetrahydropyran, and oxetane substructures. Representative Minisci reactions are reported for select examples.
authors.affiliation: Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6323, United States.
authors.forename: Marc
authors.initials: M
authors.lastname: Presset
authors.forename: Nicolas
authors.initials: N
authors.lastname: Fleury-Brégeot
authors.forename: Daniel
authors.initials: D
authors.lastname: Oehlrich
authors.forename: Frederik
authors.initials: F
authors.lastname: Rombouts
authors.forename: Gary A
authors.initials: GA
authors.lastname: Molander
mesh_terms: D001896:Boron Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D006845:Hydrocarbons, Fluorinated / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
chemical_list: D001896:Boron Compounds; D006571:Heterocyclic Compounds; D006845:Hydrocarbons, Fluorinated; D003300:Copper