title: Primary gastric tuberculosis mimicking gastric cancer: a case report.
abstract: Gastric tuberculosis is an uncommon manifestation of extra-pulmonary tuberculosis infection. The clinical signs of this type of infection are nonspecific and misleading. Clinically gastric tuberculosis resembles peptic ulcer disease or malignancy. We report a case of gastric tuberculosis, which was treated as acid peptic disease, in an Iranian immunocompetent adult with no pulmonary tuberculosis, who received surgery for gastric cancer. Diagnosis was based on PCR despite the detection of negative acid-fast bacilli in the histopathologic specimen. We recommend PCR for Mycobacterium tuberculosis to be done when granuloma or caseation is detected on biopsy in patients who are suspected of having gastric malignancy or acid peptic diseases.
authors.affiliation: Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. dr.moghadam47@yahoo.com
authors.forename: Abdolkarim
authors.initials: A
authors.lastname: Ghadimi Moghadam
authors.forename: Abdolvahab
authors.initials: A
authors.lastname: Alborzi
authors.forename: Gholam
authors.initials: G
authors.lastname: Pouladfar
authors.forename: Ahmad
authors.initials: A
authors.lastname: Monabati
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D003951:Diagnostic Errors; D005743:Gastrectomy; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology; D006099:Granuloma / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D012293:Rifampin / Q000627:therapeutic use; D013274:Stomach Neoplasms / Q000601:surgery; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
chemical_list: D000995:Antitubercular Agents; D012293:Rifampin