title: Outcomes of trabeculectomy in juvenile open angle glaucoma.
abstract: OBJECTIVE
  This study was aimed at reporting the outcomes of trabeculectomy in primary juvenile open angle glaucoma (JOAG).
  
  
  METHODS
  This study was a retrospective noncomparative case series.
  
  
  METHODS
  We included 60 eyes of 41 JOAG patients who underwent primary trabeculectomy without mitomycin-C (MMC) between 1995 and 2007. The primary outcome was success, defined as complete, if intraocular pressure (IOP) was >5 and ≤ 21 mmHg without medications or qualified if IOP was >5 and ≤ 21 mmHg with or without antiglaucoma medications. Secondary outcome measures were mean and percentage IOP reduction, complications, and risk factors for the failure of trabeculectomy.
  
  
  RESULTS
  The mean (± standard deviation) age at presentation was 24.1 ± 6.8 years (range, 12-35). Mean follow-up was 67 ± 41 months (range, 12-156). At 1 year, the probability of complete success was 92% (n = 56, 95% CI: 81-96%), at 3 years it was 89% (n = 47, 95% CI: 78-95%), and at the end of 5 years, it was 80% (n = 34, 95% CI: 65-89%). The probability of qualified success was 100% (n = 60) at 1 year, 98% (n = 51, 95% CI: 87-100%) at 3 years, and 96% (n = 36, 95% CI: 84-99%) at the end of 5 years. The mean IOP reduced from 35 ± 10 to 13 ± 2.5 mmHg (P < 0.001) after trabeculectomy. There was no serious postoperative complication. Young age was the only significant risk factor associated with the failure (odds ratio = 0.89, P = 0.03).
  
  
  CONCLUSIONS
  Primary trabeculectomy without MMC has good success rates in JOAG.
authors.forename: Daizy
authors.initials: D
authors.lastname: Pathania
authors.affiliation: VST Glaucoma Center, L. V. Prasad Eye Institute, Hyderabad, India.
authors.forename: Sirisha
authors.initials: S
authors.lastname: Senthil
authors.forename: Harsha L
authors.initials: HL
authors.lastname: Rao
authors.forename: Anil K
authors.initials: AK
authors.lastname: Mandal
authors.forename: Chandra Sekhar
authors.initials: CS
authors.lastname: Garudadari
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D012189:Retrospective Studies; D013997:Time Factors; D014065:Tonometry, Ocular; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult