title: A squaric acid-stimulated electrocatalytic reaction for sensing biomolecules with cycling signal amplification.
abstract: Squaric acid, a 2-dimensional planar structure of squarate C4O4 units linked by protons in a layered sheet, was utilized for the first time as a catalytic substrate for ultrasensitive electronic determination of low-abundance proteins by coupling a target-induced electrocatalytic reaction with the in situ cycling signal amplification strategy.
authors.affiliation: Ministry of Education & Fujian Provincial Key Laboratory of Analysis and Detection of Food Safety, Department of Chemistry, Fuzhou University, Fuzhou 350108, PR China.
authors.forename: Wenqiang
authors.initials: W
authors.lastname: Lai
authors.forename: Dianping
authors.initials: D
authors.lastname: Tang
authors.forename: Libing
authors.initials: L
authors.lastname: Fu
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Que
authors.forename: Junyang
authors.initials: J
authors.lastname: Zhuang
authors.forename: Guonan
authors.initials: G
authors.lastname: Chen
mesh_terms: D000911:Antibodies, Monoclonal / Q000737:chemistry; D015374:Biosensing Techniques; D002384:Catalysis; D003503:Cyclobutanes / Q000737:chemistry*; D055664:Electrochemical Techniques; D006046:Gold / Q000737:chemistry; D006108:Graphite / Q000737:chemistry; D007118:Immunoassay; D053768:Metal Nanoparticles / Q000737:chemistry; D000509:alpha-Fetoproteins / Q000032:analysis* / Q000737:chemistry
chemical_list: D000911:Antibodies, Monoclonal; D003503:Cyclobutanes; D000509:alpha-Fetoproteins; D006046:Gold; D006108:Graphite; C030042:squaric acid