title: Serotonin transporter in attention-deficit hyperactivity disorder--preliminary results from a positron emission tomography study.
abstract: The serotonin transporter (SERT) in attention-deficit hyperactivity disorder (ADHD) patients has not been explored by earlier positron emission tomography (PET) studies. We measured SERT availability in female ADHD patients (n=8) and healthy controls (n=14) with PET and [11C]MADAM as a tracer. No significant group differences in [11C]MADAM binding potential were noted.
authors.affiliation: Turku University Hospital, Department of Child Psychiatry, P.O. Box 52, 20521 Turku, Finland. linnea.karlsson@utu.fi
authors.forename: Linnea
authors.initials: L
authors.lastname: Karlsson
authors.forename: Lauri
authors.initials: L
authors.lastname: Tuominen
authors.forename: Antti
authors.initials: A
authors.lastname: Huotarinen
authors.forename: Sami
authors.initials: S
authors.lastname: Leppämäki
authors.forename: Elina
authors.initials: E
authors.lastname: Sihvola
authors.forename: Semi
authors.initials: S
authors.lastname: Helin
authors.forename: Maria
authors.initials: M
authors.lastname: Sipilä
authors.forename: Pekka
authors.initials: P
authors.lastname: Tani
authors.forename: Jussi
authors.initials: J
authors.lastname: Hirvonen
authors.forename: Jarmo
authors.initials: J
authors.lastname: Hietala
authors.forename: Hasse
authors.initials: H
authors.lastname: Karlsson
mesh_terms: D000328:Adult; D001289:Attention Deficit Disorder with Hyperactivity / Q000000981:diagnostic imaging / Q000378:metabolism*; D001596:Benzylamines / Q000493:pharmacokinetics; D001921:Brain / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology; D002250:Carbon Radioisotopes / Q000493:pharmacokinetics; D005260:Female; D006801:Humans; D008875:Middle Aged; D049268:Positron-Emission Tomography; D050486:Serotonin Plasma Membrane Transport Proteins / Q000378:metabolism*; D018709:Statistics, Nonparametric; D055815:Young Adult
chemical_list: D001596:Benzylamines; D002250:Carbon Radioisotopes; C470437:N,N-dimethyl-2-(2-amino-4-methylphenylthio)benzylamine; D050486:Serotonin Plasma Membrane Transport Proteins