title: Optimizing percutaneous coronary intervention: significance of hemorrhagic complications.
abstract: Major hemorrhage remains a frequent complication of contemporary percutaneous coronary intervention (PCI), regardless of how it is defined. Not only do hemorrhagic complications increase hospital costs, but major hemorrhage is highly predictive of 30-day and 1-year mortality. Use of bivalirudin significantly reduces hemorrhagic complication in PCI.
authors.affiliation: New York University School of Medicine, New York, New York, USA.
authors.forename: Frederick
authors.initials: F
authors.lastname: Feit
mesh_terms: D000991:Antithrombins / Q000494:pharmacology / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D006470:Hemorrhage / Q000209:etiology* / Q000401:mortality / Q000517:prevention & control; D006629:Hirudins / Q000494:pharmacology; D006801:Humans; D010446:Peptide Fragments / Q000494:pharmacology / Q000627:therapeutic use; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects* / Q000401:mortality; D011994:Recombinant Proteins / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000991:Antithrombins; D006629:Hirudins; D010446:Peptide Fragments; D011994:Recombinant Proteins; C074619:bivalirudin