title: Severe mandibular atrophy treated with a subperiosteal implant and simultaneous graft with rhBMP-2 and mineralized allograft: a case report.
abstract: A 71-year-old patient was successfully rehabilitated by means of a 3D model-derived, hydroxyapatite-coated titanium subperiosteal mandibular implant. The implant was specifically designed to allow bone augmentation. The deficient bone was simultaneously grafted with mineralized bone allograft and recombinant bone morphogenetic protein -2 (rhBMP-2). The 32-month postoperative cone beam computerized tomography follow-up showed vertical bone augmentation beneath the implant frame.
authors.affiliation: 1  Private practice, London, United Kingdom.
authors.forename: Cosimo
authors.initials: C
authors.lastname: Loperfido
authors.forename: Juan
authors.initials: J
authors.lastname: Mesquida
authors.forename: Jaime L
authors.initials: JL
authors.lastname: Lozada
mesh_terms: D000368:Aged; D064591:Allografts / Q000637:transplantation*; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging / Q000601:surgery; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D001284:Atrophy; D055396:Bone Morphogenetic Protein 2 / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000379:methods*; D020099:Coated Materials, Biocompatible / Q000737:chemistry; D054893:Cone-Beam Computed Tomography / Q000379:methods; D016299:Dental Implantation, Subperiosteal / Q000295:instrumentation / Q000379:methods*; D015921:Dental Implants; D003764:Dental Materials / Q000737:chemistry; D017267:Dental Prosthesis Design; D017886:Durapatite / Q000737:chemistry; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D011994:Recombinant Proteins / Q000627:therapeutic use; D014025:Titanium / Q000737:chemistry; D016212:Transforming Growth Factor beta / Q000627:therapeutic use*
chemical_list: D055396:Bone Morphogenetic Protein 2; D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D003764:Dental Materials; D011994:Recombinant Proteins; D016212:Transforming Growth Factor beta; C499469:recombinant human bone morphogenetic protein-2; D017886:Durapatite; D014025:Titanium
keywords: BMP; allograft; subperiosteal implant; vertical augmentation