title: Thermal stability of oligodeoxynucleotide duplexes containing l-deoxynucleotide at termini.
abstract: The effects of substituting l-deoxynucleotide for d-deoxynucleotide at duplex termini were evaluated and the terminal substitutions were found to show much less effects on duplex destabilization and to show a similar tendency in base pairing selectivity, compared with internal chiral substitutions.
authors.affiliation: Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan. urata@gly.oups.ac.jp
authors.forename: Hidehito
authors.initials: H
authors.lastname: Urata
authors.forename: Shuji
authors.initials: S
authors.lastname: Ogawa
authors.forename: Shun-Ichi
authors.initials: S
authors.lastname: Wada
mesh_terms: D002236:Carbohydrate Conformation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*; D013696:Temperature
chemical_list: D009838:Oligodeoxyribonucleotides