title: A web resource on DNA tests for canine and feline hereditary diseases.
abstract: Following the first identification of a disease-causing mutation in dogs in 1989 and the more recent completion of canine and feline genome sequences, much progress has been made in the molecular characterization of hereditary diseases in dogs and cats. To increase access to information on diagnosing hereditary diseases in dogs and cats, a web application has been developed to collect, organize and display information on available DNA tests and other supporting information, including gene and chromosomal locations, mutations, primary research citations and disease descriptions. The DNA testing information can be accessed at the URL: http://research.vet.upenn.edu/WSAVA-LabSearch. There are currently 131 molecular genetic tests available for hereditary diseases in dogs and cats offered by 43 laboratories worldwide. This tool should provide clinicians, researchers, breeders and companion animal owners with a single comprehensive, up-to-date and readily searchable webpage for information on hereditary disease testing.
authors.affiliation: School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Slutsky
authors.forename: Karthik
authors.initials: K
authors.lastname: Raj
authors.forename: Scott
authors.initials: S
authors.lastname: Yuhnke
authors.forename: Jerold
authors.initials: J
authors.lastname: Bell
authors.forename: Neale
authors.initials: N
authors.lastname: Fretwell
authors.forename: Ake
authors.initials: A
authors.lastname: Hedhammar
authors.forename: Claire
authors.initials: C
authors.lastname: Wade
authors.forename: Urs
authors.initials: U
authors.lastname: Giger
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000235:genetics*; D002415:Cats; D004247:DNA / Q000235:genetics*; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D020022:Genetic Predisposition to Disease; D020407:Internet
chemical_list: D004247:DNA
keywords: Canine; Database; Feline; Genetics; Mutations