title: Long-term physical activity trends in breast cancer survivors.
abstract: BACKGROUND
  Physical activity is associated with reduced mortality and higher quality of life in breast cancer survivors; however, limited data on the prevalence of activity and long-term trends after diagnosis are available.
  
  
  METHODS
  A multiethnic cohort of 631 women (18-64 years) with stage 0 to IIIA breast cancer was followed for 10 years. Recreational aerobic activity (MET-h/wk) was ascertained for the year before diagnosis (baseline), 24 months, 5 years, and 10 years after enrollment. Women were classified according to U.S. physical activity guidelines (≥150 min/wk moderate or ≥75 min/wk vigorous activity). The OR for meeting guidelines at 5 and 10 years according to baseline factors was estimated using logistic regression. The change in MET-h/wk was predicted using linear regression.
  
  
  RESULTS
  Prediagnosis, 34% of women met physical activity guidelines; 34.0%, 39.5%, and 21.4% met guidelines at 24 months, 5 years, and 10 years after enrollment, respectively. Less than 8% of survivors met guidelines at all follow-up periods. Over 10 years, recreational aerobic activity decreased by a mean ± SD of 4.3 ± 16.2 MET-h/wk. Meeting guidelines pre-diagnosis was strongly associated with meeting guidelines at 5 years [OR (95% confidence interval; CI): 2.76 (1.85-4.1)] and 10 years [OR (95% CI): 3.35 (2.13-5.28)]. No other demographic or prognostic factors were significantly associated with the 10-year change in MET-h/wk.
  
  
  CONCLUSIONS
  The vast majority of early breast cancer survivors do not meet national exercise recommendations 10 years postdiagnosis.
  
  
  CONCLUSIONS
  Physical activity levels are low in breast cancer survivors across the 10 years postdiagnosis; nonetheless, the predictors of activity in this population remain poorly understood.
authors.affiliation: Division of Public Health Sciences, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA 98109, USA.
authors.forename: Caitlin
authors.initials: C
authors.lastname: Mason
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Alfano
authors.forename: Ashley Wilder
authors.initials: AW
authors.lastname: Smith
authors.forename: Ching-Yun
authors.initials: CY
authors.lastname: Wang
authors.forename: Marian L
authors.initials: ML
authors.lastname: Neuhouser
authors.forename: Catherine
authors.initials: C
authors.lastname: Duggan
authors.forename: Leslie
authors.initials: L
authors.lastname: Bernstein
authors.forename: Kathy B
authors.initials: KB
authors.lastname: Baumgartner
authors.forename: Richard N
authors.initials: RN
authors.lastname: Baumgartner
authors.forename: Rachel
authors.initials: R
authors.lastname: Ballard-Barbash
authors.forename: Anne
authors.initials: A
authors.lastname: McTiernan
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000523:psychology / Q000628:therapy; D005006:Ethnicity; D015444:Exercise; D005260:Female; D005500:Follow-Up Studies; D015438:Health Behavior; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D011446:Prospective Studies; D015996:Survival Rate; D017741:Survivors / Q000523:psychology*; D013997:Time Factors