title: Effects of exercise-induced muscle damage on resting metabolic rate, sub-maximal running and post-exercise oxygen consumption.
abstract: Exercise-induced muscle damage (EIMD), described as the acute weakness of the musculature after unaccustomed eccentric exercise, increases oxidative metabolism at rest and during endurance exercise. However, it is not known whether oxygen uptake during recovery from endurance exercise is increased when experiencing symptoms of EIMD. Therefore, the purpose of this study was to investigate the effects of EIMD on physiological and metabolic responses before, during and after sub-maximal running. After a 12 h fast, eight healthy male participants completed baseline measurements comprising resting metabolic rate (RMR), indirect markers of EIMD, 10 min of sub-maximal running and 30 min of recovery to ascertain excess post-exercise oxygen consumption (EPOC). Measurements were then repeated at 24 and 48 h after 100 Smith-machine squats. Data analysis revealed significant (P<0.05) increases in muscle soreness and creatine kinase (CK) and decreases in peak knee extensor torque at 24 and 48 h after squatting exercise. Moreover, RMR, physiological, metabolic and perceptual responses during sub-maximal running and EPOC were increased in the two days after squatting exercise (P<0.05). It is suggested that the elevated RMR was a consequence of a raised energy requirement for the degradation and resynthesis of damaged muscle fibres. The increased oxygen demand during sub-maximal running after muscle damage was responsible for the increase in EPOC. Individuals engaging in unaccustomed resistance exercise that results in muscle damage should be mindful of the increases in resting energy expenditure and increased metabolic demand to exercise in the days that follow.
authors.affiliation: a Faculty of Health Sciences , Staffordshire University , Stoke-on-Trent , UK.
authors.forename: Dean Gareth
authors.initials: DG
authors.lastname: Burt
authors.forename: Kevin
authors.initials: K
authors.lastname: Lamb
authors.forename: Ceri
authors.initials: C
authors.lastname: Nicholas
authors.forename: Craig
authors.initials: C
authors.lastname: Twist
mesh_terms: D000328:Adult; D001481:Basal Metabolism / Q000502:physiology*; D003402:Creatine Kinase / Q000378:metabolism; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology; D008297:Male; D009119:Muscle Contraction / Q000502:physiology; D018482:Muscle, Skeletal / Q000503:physiopathology*; D010101:Oxygen Consumption / Q000502:physiology*; D055070:Resistance Training; D012146:Rest; D012420:Running / Q000502:physiology*; D055815:Young Adult
chemical_list: D003402:Creatine Kinase
keywords: Muscle-damaging exercise; post-exercise oxygen consumption; resting energy expenditure