title: Distinctive PET/CT features of splenic SANT.
abstract: A 44-year-old woman suffered from epigastralgia for 1 month. An abdominal sonography revealed a space-occupying lesion, about 6 cm, in the spleen. Contrast-enhanced CT revealed enhanced splenic lesions. The PET/CT showed FDG-avid multiple splenic nodules with a "prunes on bread" appearance in the maximum-intensity-projection image (MIP image). In sectional PET/CT images, a central cold area with peripheral increased FDG uptake in the splenic nodule is visible. Because splenic malignancy was suspected, laparoscopic splenectomy was performed. Histology revealed multiple nodules with angiomatoid appearance, CD31(+), CD34(+) and HHV-8(-) in the vascular space, typical for the rare sclerosing angiomatoid nodular transformation (SANT).
authors.affiliation: From the *Departments of Medicine, †Emergency Medicine, ‡Surgery, §Radiology and ¶Nuclear Medicine, Ditmanson Medical Foundation Chia-Yi Christian Hospital, Chia-Yi; ∥Department of Life Science, National Chung Cheng University, Chia-Yi, Taiwan;**College of Health Sciences, Chang Jung Christian University, Tainan; ††Center of General Education, Chia Nan University of Pharmacy & Science, Tainan; and ‡‡Medical Center and School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: Yu-Min
authors.initials: YM
authors.lastname: Feng
authors.forename: Ying Chieh
authors.initials: YC
authors.lastname: Huang
authors.forename: Chi-Wen
authors.initials: CW
authors.lastname: Tu
authors.forename: Wen-Shih
authors.initials: WS
authors.lastname: Kao
authors.forename: Dom-Gene
authors.initials: DG
authors.lastname: Tu
mesh_terms: D000328:Adult; D005260:Female; D019788:Fluorodeoxyglucose F18; D018219:Histiocytoma, Benign Fibrous / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008297:Male; D049268:Positron-Emission Tomography; D013160:Splenic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18