title: Formal regiocontrolled hydroboration of unbiased internal alkynes via borylation/allylic alkylation of terminal alkynes.
abstract: In accessing trisubstituted vinyl boronates from terminal alkynes, a propargyl directing (2-pyridyl)sulfonyl group allows terminal alkynes to undergo Cu-catalyzed B2(pin)2-borylation and subsequent Cu-catalyzed allylic alkylation with Grignard reagents without affecting the pinacolboronate moiety, thereby formally enabling a highly stereo- and regiocontrolled access to hydroboration products of unbiased dialkyl internal alkynes.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias, Universidad Autónoma de Madrid (UAM), Cantoblanco, 28049 Madrid, Spain.
authors.forename: Abraham L
authors.initials: AL
authors.lastname: Moure
authors.forename: Pablo
authors.initials: P
authors.lastname: Mauleón
authors.forename: Ramón
authors.initials: R
authors.lastname: Gómez Arrayás
authors.forename: Juan Carlos
authors.initials: JC
authors.lastname: Carretero