title: [Neonatal sepsis caused by group B streptococci: atypical and recurrent disease episodes].
abstract: Both neonates of male twins born at 30 weeks and 3 days gestation presented with late-onset sepsis caused by an infection with group B streptococci (GBS), shortly after one another. Although the younger twin recovered with a standard regimen of 10 days penicillin G i.v., the older twin had three recurrent episodes with GBS positive blood cultures. Oropharyngeal, faecal, urine, liquor and breast milk cultures were GBS negative. Using echocardiography and a PET/CT scan, a persistent endovascular focus was discovered. We treated him with penicillin G i.v. for 4 weeks, after which he recovered completely. Another male neonate born at 26 weeks gestation presented with GBS sepsis and developed an erythematous swelling of the right mandibula within 12 hours. Ultrasound revealed parotitis, which is rare in neonates (3.8 per 10,000). Risk factors for parotitis include prematurity, low birth weight and dehydration (i.e., diuretic usage). Parotitis can be complicated by abscess formation.
authors.affiliation: Reinier de Graaf Groep, afd. Kindergeneeskunde, Delft, the Netherlands. evavanzanten@gmail.com
authors.forename: Eva
authors.initials: E
authors.lastname: van Zanten
authors.forename: Sarah
authors.initials: S
authors.lastname: Dekker
authors.forename: Laura H
authors.initials: LH
authors.lastname: van der Meer-Kappelle
authors.forename: Jeroen G
authors.initials: JG
authors.lastname: Noordzij
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010309:Parotitis / Q000175:diagnosis / Q000188:drug therapy; D012008:Recurrence; D012307:Risk Factors; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000188:drug therapy*; D013292:Streptococcus agalactiae / Q000187:drug effects / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents