title: Synthesis of 3,5-bis(acrylaldehyde) boron-dipyrromethene and application in detection of cysteine and homocysteine in living cells.
abstract: Synthesis, characterization, and spectral and electrochemical properties of 3,5-bis(acrylaldehyde) BODIPY are described. The compound exhibited higher selectivity toward cysteine/homocysteine than toward other amino acids and thiol-containing compounds as shown by absorption and emission titration experiments and by experiments in living cells.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Bombay, Mumbai 400076, India.
authors.forename: Sheri
authors.initials: S
authors.lastname: Madhu
authors.forename: Rajesh
authors.initials: R
authors.lastname: Gonnade
authors.forename: Mangalampalli
authors.initials: M
authors.lastname: Ravikanth
mesh_terms: D000447:Aldehydes / Q000138:chemical synthesis / Q000737:chemistry*; D001896:Boron Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D002470:Cell Survival; D002477:Cells / Q000737:chemistry* / Q000166:cytology / Q000378:metabolism; D003545:Cysteine / Q000032:analysis*; D056945:Hep G2 Cells; D006710:Homocysteine / Q000032:analysis*; D006801:Humans; D008958:Models, Molecular; D015394:Molecular Structure; D014407:Tumor Cells, Cultured
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D000447:Aldehydes; D001896:Boron Compounds; D006710:Homocysteine; D003545:Cysteine