title: A solid-state control system for dynein-based ciliary/flagellar motility.
abstract: Ciliary and flagellar beating requires the coordinated action of multiple dyneins with different enzymatic and motor properties. In this issue, Yamamoto et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201211048) identify the MIA (modifier of inner arms) complex within the Chlamydomonas reinhardtii axoneme that physically links to a known regulatory structure and provides a signaling conduit from the radial spokes to an inner arm dynein essential for waveform determination.
authors.affiliation: Department of Molecular, Microbial, and Structural Biology, University of Connecticut Health Center, Farmington, CT 06030, USA. king@neuron.uchc.edu
authors.forename: Stephen M
authors.initials: SM
authors.lastname: King
mesh_terms: D000818:Animals; D054468:Axoneme / Q000378:metabolism; D002465:Cell Movement; D016825:Chlamydomonas reinhardtii / Q000166:cytology* / Q000378:metabolism*; D002923:Cilia / Q000378:metabolism*; D004398:Dyneins / Q000378:metabolism*; D005407:Flagella / Q000378:metabolism*; D006801:Humans; D008954:Models, Biological; D010802:Phylogeny
chemical_list: D004398:Dyneins