title: Primary anorectal melanoma: A case report with extended follow-up.
abstract: BACKGROUND
  Anorectal melanoma is a rare and aggressive disease. The mainstay of treatment is usually surgical with curative or palliative intent, since radio- and chemotherapy do not really improve the outcome. The poor prognosis is attributable to delay in diagnosis and its inherent biologic aggressiveness.
  
  
  METHODS
  We present a case of anorectal melanoma in a 68-year-old man who underwent solely abdominoperineal amputation and was doing well 30 months after surgery, without any evidence of recurrent disease.
  
  
  CONCLUSIONS
  Treatment of anorectal melanoma should be by the least morbid means possible. Surgical procedure that can achieve a complete local excision and respect the functional aspects and quality of life of the patient remains the best therapeutic approach. No systemic regimen for metastatic anorectal melanoma is considered standard of care.
authors.affiliation: Department of Medical Oncology, Salah Azaiez Institute, Bab Saadoun, Tunis, Tunisia.
authors.forename: Aymen
authors.initials: A
authors.lastname: Lagha
authors.forename: Mouna
authors.initials: M
authors.lastname: Ayadi
authors.forename: Sarra
authors.initials: S
authors.lastname: Krimi
authors.forename: Nesrine
authors.initials: N
authors.lastname: Chraiet
authors.forename: Bassem
authors.initials: B
authors.lastname: Allani
authors.forename: Hela
authors.initials: H
authors.lastname: Rifi
authors.forename: Henda
authors.initials: H
authors.lastname: Raies
authors.forename: Amel
authors.initials: A
authors.lastname: Mezlini
keywords: anorectal neoplasm; immunohistochemistry; malignant melanoma; surgical treatment