title: A retrospective and consecutive study of viscocanalostomy versus trabeculectomy for primary congenital glaucoma.
abstract: BACKGROUND
  Surgical interventions are the main treatment for primary congenital glaucoma (PCG). This study aimed to compare the efficacy and safety between viscocanalostomy and mitomycin C (MMC)-trabeculectomy in patients with PCG.
  
  
  METHODS
  A total number of 43 patients with PCG who underwent either viscocanalostomy (group 1) or MMC- trabeculectomy (group 2) between June 2003 and June 2008 were retrospectively reviewed. The patients' intraocular pressures (IOPs) were examined before surgery and on day 1, week 1, month 1, month 6, and month 12 post-operative. Mean horizontal corneal diameters, success rates, intra- and post-operative complications were compared between the two groups.
  
  
  RESULTS
  Pre-operative IOPs were (31.96 ± 3.90) mmHg in group 1 and (32.56 ± 4.00) mmHg in group 2. At the last visit, IOPs were (16.78 ± 2.20) mmHg and (15.77 ± 2.60) mmHg, respectively (P < 0.001); the complete success rates of group 1 and group 2 were 45.9% and 67.4%, respectively, and the difference was not statistically significant (P = 0.158). There were no major complications occurred in the two groups.
  
  
  CONCLUSIONS
  Both viscocanalostomy and trabeculectomy can lower IOP in PCG patients effectively. Although there was no major complications occurred in both groups, viscocanlostomy may decrease the probability of postoperative haemorrhage, hypotony, cataract, or choroid effusion.
authors.affiliation: Department of Ophthalmology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Chen
authors.forename: Yan
authors.initials: Y
authors.lastname: Yu
authors.forename: Hong
authors.initials: H
authors.lastname: Sun
authors.forename: Yuan
authors.initials: Y
authors.lastname: Zong
authors.forename: Zhi-lan
authors.initials: ZL
authors.lastname: Yuan
mesh_terms: D005260:Female; D018463:Filtering Surgery / Q000009:adverse effects / Q000379:methods*; D005901:Glaucoma / Q000151:congenital* / Q000601:surgery*; D006801:Humans; D007223:Infant; D007429:Intraocular Pressure; D008297:Male; D012189:Retrospective Studies; D014130:Trabeculectomy / Q000009:adverse effects / Q000379:methods*