title: [Case report: Purulent pericarditis caused by candida species--a rare but life-threatening disease in intensive care medicine].
abstract: We report a case of a male patient with drug abuse in his medical history who was hospitalized because of a community acquired pneumonia. Subsequently the patient developed an acute lung injury (ARDS) and a fulminant purulent pericarditis accompanied by a pericardial effusion. Caused by the pericardial tamponade cardiac function was severely restricted. Due to fast diagnosis and immediate adequate therapy such as systemic anti-fungal treatment, pericardiocentesis, percutaneous drainage, and later surgical intervention the patient was treated successfully. This article describes etiology, pathophysiology and symptoms of purulent Candida-pericarditis and gives a review of existing literature regarding this extremely rare disease. In addition therapeutic options are discussed.
authors.affiliation: Abteilung für Anästhesiologie und Intensivmedizin der Park-Klinik Weissensee, Berlin. hensel@park-klinik.com
authors.forename: Mario
authors.initials: M
authors.lastname: Hensel
authors.forename: Remco
authors.initials: R
authors.lastname: Reinartz
authors.forename: Christina
authors.initials: C
authors.lastname: Koch
authors.forename: Irit
authors.initials: I
authors.lastname: Nachtigall
authors.forename: Rudolf
authors.initials: R
authors.lastname: Marnitz
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D041221:Candida glabrata; D002177:Candidiasis / Q000382:microbiology* / Q000601:surgery / Q000628:therapy*; D000077336:Caspofungin; D017714:Community-Acquired Infections / Q000382:microbiology / Q000628:therapy; D003422:Critical Care; D004322:Drainage; D054714:Echinocandins / Q000627:therapeutic use; D004632:Emergency Medical Services; D006801:Humans; D055666:Lipopeptides; D008297:Male; D008875:Middle Aged; D020519:Pericardiocentesis; D010493:Pericarditis / Q000382:microbiology* / Q000601:surgery / Q000628:therapy*; D011379:Prognosis; D012128:Respiratory Distress Syndrome / Q000209:etiology / Q000628:therapy; D019966:Substance-Related Disorders / Q000150:complications; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D000666:Amphotericin B; D000077336:Caspofungin