title: An atom-economical and stereoselective domino synthesis of functionalised dienes.
abstract: Open sesame: A direct synthesis of functionalised and stereodefined dienes, relying on a domino allylic alkylation/electrocyclic ring-opening sequence, is reported. This method allows concise access to doubly vinylogous esters. A further systematic study of ring-opening rates of carbon-substituted cyclobutenes allowed the design of substrates amenable to sequential pericyclic reactions (see scheme).
authors.affiliation: Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470 Mülheim an der Ruhr, Germany.
authors.forename: Caroline
authors.initials: C
authors.lastname: Souris
authors.forename: Marco
authors.initials: M
authors.lastname: Luparia
authors.forename: Frédéric
authors.initials: F
authors.lastname: Frébault
authors.forename: Davide
authors.initials: D
authors.lastname: Audisio
authors.forename: Christophe
authors.initials: C
authors.lastname: Farès
authors.forename: Richard
authors.initials: R
authors.lastname: Goddard
authors.forename: Nuno
authors.initials: N
authors.lastname: Maulide