title: Bilateral total optic atrophy due to transdermal methanol intoxication.
abstract: In this case report, we document a 54-year-old woman with total bilateral optic nerve atrophy after local application of methanol containing spirit. Almost all the reported cases of methanol intoxication in the literature are caused by oral ingestion. In this rare case, we present transdermal absorption of methanol that may cause irreversible blindness in addition to intracerebral lesions.
authors.affiliation: Department of Ophthalmology, Batman State Hospital, Batman, Turkey.
authors.forename: Yalçin
authors.initials: Y
authors.lastname: Işcan
authors.forename: Çiğdem
authors.initials: Ç
authors.lastname: Coşkun
authors.forename: Veysi
authors.initials: V
authors.lastname: Öner
authors.forename: Fatih Mehmet
authors.initials: FM
authors.lastname: Türkçü
authors.forename: Mehmet
authors.initials: M
authors.lastname: Taş
authors.forename: Mehmet Fuat
authors.initials: MF
authors.lastname: Alakuş
mesh_terms: D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D000432:Methanol / Q000009:adverse effects*; D008875:Middle Aged; D009896:Optic Atrophy / Q000139:chemically induced* / Q000175:diagnosis; D012869:Skin Absorption / Q000187:drug effects*; D012997:Solvents / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed; D014065:Tonometry, Ocular
chemical_list: D012997:Solvents; D000432:Methanol
keywords: Methanol Intoxication; Optic Atrophy; Transdermal Absorption