title: Selection and timing for invasive therapy in non-ST-segment-elevation acute coronary syndrome.
abstract: While outcomes for ST-segment-elevation myocardial infarction has significantly decreased over the last years, patients presenting with non-ST-segment-elevation acute coronary syndromes (NSTEACS) still have a rather high mortality. Longer term mortality over 4 years is about double the mortality after a ST-segment-elevation myocardial infarction. The reason for the poorer prognosis is unclear but is very likely to be partially explained by the generally older age of NSTEACS patients. The optimal therapy for NSTEACS is less well defined. In this review, the authors specifically discuss the role of coronary angiography, how to decide which patient should undergo this procedure and whether there is an optimal time point. The review provides an up-to-date discussion about the best treatment strategies for NSTEACS.
authors.affiliation: Cardiovascular Division, Yale Medical School, Division of Cardiology, New Haven, CT 06510, USA.
authors.forename: Pascal
authors.initials: P
authors.lastname: Meier
authors.forename: Georg M
authors.initials: GM
authors.lastname: Fröhlich
authors.forename: Stephanie
authors.initials: S
authors.lastname: Meller
authors.forename: Rodney
authors.initials: R
authors.lastname: De Palma
authors.forename: Alexandra J
authors.initials: AJ
authors.lastname: Lansky
mesh_terms: D054058:Acute Coronary Syndrome / Q000175:diagnosis / Q000628:therapy*; D000367:Age Factors; D000789:Angina, Unstable / Q000175:diagnosis / Q000628:therapy*; D017023:Coronary Angiography; D004562:Electrocardiography; D006801:Humans; D009203:Myocardial Infarction / Q000175:diagnosis / Q000628:therapy*; D018579:Patient Selection; D062645:Percutaneous Coronary Intervention / Q000379:methods*; D018570:Risk Assessment; D013997:Time Factors