title: One-step synthesis of peptide-programmed QDs as ready-to-use nanoprobes.
abstract: We developed a facile one-step method to produce ready-to-use quantum dots based on a peptide sequence containing a hexahistidine(his6-tag), poly(ethylene glycol) (PEG), and a functional group, which lead to stable and customized peptide-QDs conjugates that could serve as fluorescent nanoprobes for biological imaging and detection.
authors.affiliation: Department of Pharmaceutical Sciences, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou, Guangdong 510515, PR China.
authors.forename: Jing
authors.initials: J
authors.lastname: Jia
authors.forename: Pengfei
authors.initials: P
authors.lastname: Zhang
authors.forename: Duyang
authors.initials: D
authors.lastname: Gao
authors.forename: Zonghai
authors.initials: Z
authors.lastname: Sheng
authors.forename: Dehong
authors.initials: D
authors.lastname: Hu
authors.forename: Ping
authors.initials: P
authors.lastname: Gong
authors.forename: Chunlei
authors.initials: C
authors.lastname: Wu
authors.forename: Jianhai
authors.initials: J
authors.lastname: Chen
authors.forename: Lintao
authors.initials: L
authors.lastname: Cai
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004354:Drug Screening Assays, Antitumor; D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D045663:Quantum Dots; D013329:Structure-Activity Relationship; D013499:Surface Properties
chemical_list: D000970:Antineoplastic Agents; D005456:Fluorescent Dyes; D010455:Peptides