title: Characteristics and prognosis of ovarian metastatic tumors: review of a single-institution experience.
abstract: BACKGROUND
  To evaluate the clinico-pathological characteristics and role of surgery in patients with ovarian metastasis.
  
  
  METHODS
  Clinical data from 51 patients with pathologically confirmed ovarian metastasis were reviewed.
  
  
  RESULTS
  Ovarian metastasis accounted for 14% of all malignant ovarian neoplasms (51/364). Of the 51 metastatic ovarian tumor cases, 24 originated from gynecologic malignancies, while 27 originated from non-gynecologic malignancies. Optimal cytoreduction was performed in 88% and 37% of patients with metastases of gynecologic and non-gynecologic origin, respectively. Patients with ovarian metastasis had a two-year survival rate in 82% of the gynecologic group and 70% of the non-gynecologic group (p = 0.35). The five-year survival rate of patients with non-gynecologic tumor origin (29%) was significantly worse (p = 0.04) than the survival rates of those with tumors of gynecologic origin (61%). In the non-gynecologic group, the five-year survival rates were significantly different between patients who were performed optimal cytoreductive surgery vs those without this procedure (42% and 20%, respectively; p = 0.04).
  
  
  CONCLUSIONS
  Although complete surgical resection is not achievable in approximately two-thirds of patients with metastases of non-gynecological origin, optimal tumor cytoreduction appears to improve survival, which is statistically significant in all patients with ovarian metastatic tumors.
authors.affiliation: Department of Obstetrics and Gynecology, Oncology Unit, Bakirkoy Woman and Children's Training and Research Hospital, Istanbul, Turkey. drvolkanulker@yahoo.com
authors.forename: V
authors.initials: V
authors.lastname: Ulker
authors.forename: C
authors.initials: C
authors.lastname: Numanoglu
authors.forename: V
authors.initials: V
authors.lastname: Alpay
authors.forename: O
authors.initials: O
authors.lastname: Akbayir
authors.forename: I
authors.initials: I
authors.lastname: Polat
authors.forename: A
authors.initials: A
authors.lastname: Gedikbasi
authors.forename: A
authors.initials: A
authors.lastname: Akca
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery; D011379:Prognosis; D015996:Survival Rate