title: The cost-effectiveness of prenatal detection for congenital heart disease using telemedicine screening.
abstract: We estimated the longer-term cost-effectiveness of using telemedicine screening for prenatal detection of congenital heart disease (CHD). One hospital in south-east England with a telemedicine service was connected to a fetal cardiology unit in London. A UK health service perspective was adopted. Evidence on costs and outcomes for standard-risk pregnant women during the antenatal period was based on patient-level data. Extrapolation beyond the end of the study (just after delivery) was carried out for the lifetime of children born with and without CHD. Expert opinion and data from published sources was used to populate a decision model. Future costs and benefits were discounted. The main outcome was quality-adjusted life years (QALYs) and results were expressed as cost per QALY gained. Various one-way sensitivity analyses were conducted. The model showed that offering telemedicine screening by specialists to all standard-risk pregnant women was the dominant strategy (i.e. cheaper and more effective). The sensitivity analyses found that the model was robust, and that telemedicine remained the most cost-effective strategy. The study showed that it would be cost-effective to provide telemedicine examinations as part of an antenatal screening programme for all standard-risk women.
authors.affiliation: Health Economics Unit, University of Birmingham, Birmingham, UK.
authors.forename: Hema
authors.initials: H
authors.lastname: Mistry
authors.forename: Helena M
authors.initials: HM
authors.lastname: Gardiner
mesh_terms: D003362:Cost-Benefit Analysis; D005260:Female; D006330:Heart Defects, Congenital / Q000175:diagnosis*; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000191:economics* / Q000379:methods*; D015203:Reproducibility of Results; D017216:Telemedicine / Q000191:economics / Q000379:methods*; D006113:United Kingdom