title: Postprandial triglyceride and free fatty acid metabolism in obese women after either endurance or resistance exercise.
abstract: We investigated the effects of two exercise modalities on postprandial triglyceride (TG) and free fatty acid (FFA) metabolism. Sedentary, obese women were studied on three occasions in randomized order: endurance exercise for 60 min at 60-65% aerobic capacity (E), ~60 min high-intensity resistance exercise (R), and a sedentary control trial (C). After exercise, a liquid-mixed meal containing [U-(13)C]palmitate was consumed, and subjects were studied over 7 h. Isotopic enrichment (IE) of plasma TG, plasma FFA, and breath carbon dioxide compared with meal IE indicated the contribution of dietary fat to each pool. Total and endogenously derived plasma TG content was reduced significantly in both E and R compared with C (P < 0.05), with no effect of exercise on circulating exogenous (meal-derived) TG content. Exogenous plasma FFA content was increased significantly following both E and R compared with C (P < 0.05), whereas total and endogenous FFA concentrations were elevated only in E (P < 0.05) compared with C. Fatty acid (FA) oxidation rates were increased significantly after E and R compared with C (P < 0.05), with no difference between exercise modalities. The present results indicate that E and R may be equally effective in reducing postprandial plasma TG concentration and enhancing lipid oxidation when the exercise sessions are matched for duration rather than for energy expenditure. Importantly, tracer results indicated that the reduction in postprandial lipemia after E and R exercise bouts is not achieved by enhanced clearance of dietary fat but rather, is achieved by reduced abundance of endogenous FA in plasma TG.
authors.affiliation: Department of Exercise Science and Sport Studies, Rutgers University, New Brunswick, New Jersey 08901, USA.
authors.forename: Patrick M
authors.initials: PM
authors.lastname: Davitt
authors.forename: Shawn M
authors.initials: SM
authors.lastname: Arent
authors.forename: Marc A
authors.initials: MA
authors.lastname: Tuazon
authors.forename: Devon L
authors.initials: DL
authors.lastname: Golem
authors.forename: Gregory C
authors.initials: GC
authors.lastname: Henderson
mesh_terms: D000328:Adult; D001481:Basal Metabolism / Q000502:physiology; D004041:Dietary Fats / Q000378:metabolism; D015444:Exercise / Q000502:physiology*; D005230:Fatty Acids, Nonesterified / Q000097:blood / Q000378:metabolism*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000378:metabolism / Q000503:physiopathology; D050356:Lipid Metabolism / Q000502:physiology; D009765:Obesity / Q000378:metabolism* / Q000503:physiopathology*; D010084:Oxidation-Reduction; D010807:Physical Endurance / Q000502:physiology*; D019518:Postprandial Period / Q000502:physiology*; D014280:Triglycerides / Q000097:blood / Q000378:metabolism*; D055815:Young Adult
chemical_list: D004041:Dietary Fats; D005230:Fatty Acids, Nonesterified; D014280:Triglycerides
keywords: adiposity; fat oxidation; indirect calorimetry; isotopes; physical activity