title: Guards at the gate to embryonic stem cell differentiation.
abstract: A core network of genes maintaining pluripotency has been at least partially defined. How the genetic switch is flipped to differentiation is the subject of a new study that reveals some unexpected players.
authors.affiliation: Institute of Medical Biology, A(∗)STAR (Agency for Science, Technology and Research), 8A Biomedical Grove, #06-06 Immunos, Singapore 138648, Singapore.
authors.forename: Norihiro
authors.initials: N
authors.lastname: Tsuneyoshi
authors.forename: N Ray
authors.initials: NR
authors.lastname: Dunn