title: Estimation of birth population-based perinatal-neonatal mortality and preterm rate in China from a regional survey in 2010.
abstract: OBJECTIVE
  To estimate birth population-based perinatal-neonatal mortality and preterm rate in China from a regional survey in 2010.
  
  
  METHODS
  Data of total births in 2010 obtained from 151 level I-III hospitals in Huai'an, Jiangsu, were prospectively collected and analyzed.
  
  
  RESULTS
  From 61,227 birth registries (including 60,986 live births and 241 stillbirths), we derive a birth rate of 11.3‰ (of 5.4 million regional population), a male-to-female ratio of 116:100 and valid data from 60,615 newborns. Mean birth weight (BW) was 3441 ± 491 g with 13.6% macrosomia. Low BW was 2.8% (1691/60,372) with 8.83% mortality. Preterm rate was 3.72% (2239/60,264) with 7.61% mortality. Cesarean section rate was 52.9% (31,964/60,445), multiple pregnancy 1.8% (1088/60,567) and birth defects 6.7‰ (411/61,227). There were 97.4% healthy newborns and 2.2% (1298) requiring hospitalized after birth. The perinatal mortality was 7.7‰ (471/61,227, including 241 stillbirths, 230 early neonatal deaths). The neonatal mortality was 4.4‰ (269/60,986). The main causes of neonatal death were birth asphyxia (24.5%), respiratory diseases (21.5%), prematurity related organ dysfunction (18.5%) and congenital anomalies (7.7%), whereas incidence of congenital heart disease and respiratory distress syndrome was 8.6‰ and 6.1‰, respectively.
  
  
  CONCLUSIONS
  This regional birth population-based data file contains low perinatal-neonatal mortality rates, associated with low proportion of LBW and preterm births, and incidences of major neonatal disease, by which we estimate, in a nationwide perspective, in 16 million annual births, preterm births should be around 800,000, perinatal and neonatal mortality may be 128,000-144,000 and 80,000-96,000, respectively, along with 100,000 respiratory distress syndrome.
authors.affiliation: Departments of Neonatology, Children's Hospital and the Institutes of Biomedical Sciences, Fudan University, and the Laboratory of Neonatal Medicine, Ministry of Health , Shanghai , P.R. China .
authors.forename: L
authors.initials: L
authors.lastname: Sun
authors.forename: H
authors.initials: H
authors.lastname: Yue
authors.forename: B
authors.initials: B
authors.lastname: Sun
authors.forename: L
authors.initials: L
authors.lastname: Han
authors.forename: M
authors.initials: M
authors.lastname: Qi
authors.forename: Z
authors.initials: Z
authors.lastname: Tian
authors.forename: S
authors.initials: S
authors.lastname: Lu
authors.forename: C
authors.initials: C
authors.lastname: Shan
authors.forename: J
authors.initials: J
authors.lastname: Luo
authors.forename: Y
authors.initials: Y
authors.lastname: Fan
authors.forename: S
authors.initials: S
authors.lastname: Li
authors.forename: M
authors.initials: M
authors.lastname: Dong
authors.forename: X
authors.initials: X
authors.lastname: Zuo
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: W
authors.initials: W
authors.lastname: Lin
authors.forename: J
authors.initials: J
authors.lastname: Xu
authors.forename: Y
authors.initials: Y
authors.lastname: Heng
mesh_terms: D000328:Adult; D001034:Apgar Score; D002681:China / Q000453:epidemiology; D003625:Data Collection; D005260:Female; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology; D008297:Male; D036801:Parturition; D054238:Perinatal Mortality; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology; D011256:Pregnancy Outcome / Q000453:epidemiology; D047928:Premature Birth / Q000453:epidemiology*; D055815:Young Adult