title: A dosimetric comparative study: volumetric modulated arc therapy vs intensity-modulated radiation therapy in the treatment of nasal cavity carcinomas.
abstract: The purpose of this study was to evaluate the differences between volumetric modulated arc therapy (VMAT) and intensity-modulated radiation therapy (IMRT) in the treatment of nasal cavity carcinomas. The treatment of 10 patients, who had completed IMRT treatment for resected tumors of the nasal cavity, was replanned with the Philips Pinnacle(3) Version 9 treatment-planning system. The IMRT plans used a 9-beam technique whereas the VMAT (known as SmartArc) plans used a 3-arc technique. Both types of plans were optimized using Philips Pinnacle(3) Direct Machine Parameter Optimization algorithm. IMRT and VMAT plans' quality was compared by evaluating the maximum, minimum, and mean doses to the target volumes and organs at risk, monitor units (MUs), and the treatment delivery time. Our results indicate that VMAT is capable of greatly reducing treatment delivery time and MUs compared with IMRT. The reduction of treatment delivery time and MUs can decrease the effects of intrafractional uncertainties that can occur because of patient movement during treatment delivery. VMAT's plans further reduce doses to critical structures that are in close proximity to the target volume.
authors.affiliation: School of Health Professions, Medical Dosimetry Program, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. khamdiep@gmail.com
authors.forename: Kham
authors.initials: K
authors.lastname: Nguyen
authors.forename: David
authors.initials: D
authors.lastname: Cummings
authors.forename: Vincent C
authors.initials: VC
authors.lastname: Lanza
authors.forename: Kathleen
authors.initials: K
authors.lastname: Morris
authors.forename: Congjun
authors.initials: C
authors.lastname: Wang
authors.forename: Jordan
authors.initials: J
authors.lastname: Sutton
authors.forename: John
authors.initials: J
authors.lastname: Garcia
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods*
keywords: 3-Arc; IMRT; Nasal cavity carcinomas; VMAT