title: Motor nerve impairment in diabetic patients with symmetrical distal sensory polyneuropathy: a single nerve fiber conduction velocity study.
abstract: BACKGROUND
  In this study we investigated the clinical utility of single fiber conduction velocity (SF-CV) testing in the evaluation of motor nerve function in diabetic patients with signs and symptoms of symmetrical distal sensory polyneuropathy (DSP). SF-CV findings were compared with conventional nerve conduction studies (NCS).
  
  
  METHODS
  Twenty-eight consecutive type 2 diabetic patients with clinically diagnosed DSP were studied.
  
  
  RESULTS
  SF-CV testing of the tibial nerve was abnormal in 16 (57.1%) patients. Twelve patients with normal conventional motor NCS had abnormal findings by tibial SF-CV. SF-CV testing of the tibial nerve was significantly superior to all other motor NCS.
  
  
  CONCLUSIONS
  SF-CV testing of the tibial nerve often demonstrates motor nerve impairment in diabetic patients with sensory DSP when conventional NCS are normal.
authors.affiliation: Department of Neurology, Marmara University, Mimar Sinan Cad., Fevzi Çakmak Mah., Üst Kaynarca-Pendik, Istanbul, Turkey.
authors.forename: Gulin
authors.initials: G
authors.lastname: Sunter
authors.forename: Kayihan
authors.initials: K
authors.lastname: Uluc
authors.forename: Celal
authors.initials: C
authors.lastname: Salcini
authors.forename: Cagri Mesut
authors.initials: CM
authors.lastname: Temucin
authors.forename: Orhan
authors.initials: O
authors.lastname: Yilmaz
authors.forename: Tulin
authors.initials: T
authors.lastname: Tanridag
authors.forename: Onder
authors.initials: O
authors.lastname: Us
authors.forename: Luca
authors.initials: L
authors.lastname: Padua
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D003928:Diabetic Nephropathies / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D004594:Electrophysiology / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology*; D009412:Nerve Fibers / Q000502:physiology*; D009431:Neural Conduction / Q000502:physiology*; D013979:Tibial Nerve / Q000503:physiopathology; D014459:Ulnar Nerve / Q000503:physiopathology
keywords: conventional nerve conduction study; diabetes mellitus; distal symmetrical sensory polyneuropathy; motor nerve impairment; single fiber conduction velocity