title: [Vancomycin-induced DRESS syndrome: a case report].
abstract: DRESS syndrome is a severe adverse drug-induced reaction, characterized by generalized skin rash associated with hypereosinophilia, lymphocytosis and internal organ involvement. Antiepileptics, sulfamides and allopurinol are the most frequently reported drugs; vancomycin is less common. We report a case of vancomycin-induced DRESS syndrome in a 69-year-old male patient. Clinical symptoms and diagnosis difficulties are reported through this observation as well as pathogenesis and treatment of this syndrom.
authors.affiliation: Laboratoire de biologie médicale, CH de Bretagne Sud, Lorient, France. m.cariou@ch-bretagne-sud.fr
authors.forename: Marie-Estelle
authors.initials: ME
authors.lastname: Cariou
authors.forename: Mohamed
authors.initials: M
authors.lastname: Kaabar
authors.forename: Pauline
authors.initials: P
authors.lastname: Cailliez
authors.forename: Aurélien
authors.initials: A
authors.lastname: Lorléac'h
authors.forename: Nathalie
authors.initials: N
authors.lastname: Prades-Grandgirard
authors.forename: Caroline
authors.initials: C
authors.lastname: Jacobzone-Lévêque
authors.forename: François
authors.initials: F
authors.lastname: Schmitt
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D004697:Endocarditis, Bacterial / Q000188:drug therapy* / Q000473:pathology; D004802:Eosinophilia / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D005076:Exanthema / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D014640:Vancomycin / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin
keywords: DRESS; Human Herpes Virus-6; drug-induced hypersensitivity syndrome; hypereosinophilia; vancomycin