title: Gastrostomy in children with cystic fibrosis and portal hypertension.
abstract: Children with cystic fibrosis-associated liver disease (CFALD) and portal hypertension may require supplemental feeding with gastrostomy; however, this could lead to the development of stomal varices. We assessed this risk and nutritional and pulmonary outcome in a series of 7 children with CFALD and portal hypertension. In 35.1 patient-years of follow-up, none developed stomal varices or had a gastrointestinal bleed attributable to a varix. There was significant improvement in nutrition and lung function 2 years postinsertion. We conclude that gastrostomy placement for poor nutrition in children with CFALD and portal hypertension is safe and contributes to improved nutritional and pulmonary outcome.
authors.affiliation: Department of Respiratory Medicine, Royal Children's Hospital, Parkville, Victoria, Australia.
authors.forename: Moya
authors.initials: M
authors.lastname: Vandeleur
authors.forename: John
authors.initials: J
authors.lastname: Massie
authors.forename: Mark
authors.initials: M
authors.lastname: Oliver
mesh_terms: D000293:Adolescent; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications / Q000503:physiopathology / Q000601:surgery* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D005774:Gastrostomy / Q000009:adverse effects*; D006801:Humans; D006975:Hypertension, Portal / Q000209:etiology / Q000601:surgery* / Q000628:therapy; D008107:Liver Diseases / Q000209:etiology / Q000601:surgery* / Q000628:therapy; D008168:Lung / Q000503:physiopathology; D008297:Male; D009752:Nutritional Status; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D018570:Risk Assessment; D016896:Treatment Outcome