title: [Effect of compound whole grain-soybean on oxidative stress].
abstract: OBJECTIVE
  To observe the in vitro oxidation resistance of compound whole grain and the effect on improving the disorder of lipid metabolism and the oxidative stress in rats.
  
  
  METHODS
  Make extracting of compound whole grain, rice, flour and black rice, method use chemical colorimetry to detect total antioxidant capacity, hydroxyl radical (*OH) and superoxide anion (O2-*). Forty-four male SD rats were divided into four groups in random: negative control group, model control group, white rice-flour group and compound whole grain. All 4 groups were fed for 8 weeks with different experimental diets. Weight, total cholesterol (TC), triglyceride (TG ), high density lipoprotein cholesterol (HDL-C) were detected in serum. Malondialdehyde (MDA), total antioxidant capacity (T-AOC), super oxygen dehydrogenizes (SOD), glutathione peroxidase (GSH-Px) were detected in serum and liver.
  
  
  RESULTS
  The T-AOC, the ability of body cleaning hydroxyl radical and superoxide anion were enhanced,quite with the black rice. In all 3 treatment groups, compound whole grain group had higher HDL-C, T-AOC, SOD, GSH-Px, while TC, TG, MDA were lower. Compared with negative control groups, there is no significant difference.
  
  
  CONCLUSIONS
  Compound whole grain can have good effect on oxidative stress. This effect is the important mechanism of lipid metabolism disorders.
authors.affiliation: School of Public Health, Southeast University, Nanjing 210009, China. zhousiyu5370053@126.com
authors.forename: Siyu
authors.initials: S
authors.lastname: Zhou
authors.forename: Chengkai
authors.initials: C
authors.lastname: Zhai
authors.forename: Mingxia
authors.initials: M
authors.lastname: Jiang
authors.forename: Haifeng
authors.initials: H
authors.lastname: Zhang
authors.forename: Hong
authors.initials: H
authors.lastname: Zhang
authors.forename: Shufen
authors.initials: S
authors.lastname: Han
authors.forename: Wen
authors.initials: W
authors.lastname: Liu
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000818:Animals; D006949:Hyperlipidemias / Q000517:prevention & control*; D050356:Lipid Metabolism / Q000187:drug effects*; D008297:Male; D012275:Oryza / Q000737:chemistry; D018384:Oxidative Stress / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013025:Glycine max / Q000737:chemistry*; D014908:Triticum / Q000737:chemistry
chemical_list: D010936:Plant Extracts