title: A vitamin-responsive mesoporous nanocarrier with DNA aptamer-mediated cell targeting.
abstract: A smart drug delivery system with cancer cell targeting and bioresponsive controlled drug release has been constructed by taking advantage of a protein-capped mesoporous nanovalve and a DNA aptamer.
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China.
authors.forename: Le-Le
authors.initials: LL
authors.lastname: Li
authors.forename: Mengying
authors.initials: M
authors.lastname: Xie
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
authors.forename: Xinyang
authors.initials: X
authors.lastname: Li
authors.forename: Cheng
authors.initials: C
authors.lastname: Wang
authors.forename: Quan
authors.initials: Q
authors.lastname: Yuan
authors.forename: Dai-Wen
authors.initials: DW
authors.lastname: Pang
authors.forename: Yi
authors.initials: Y
authors.lastname: Lu
authors.forename: Weihong
authors.initials: W
authors.lastname: Tan
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry*; D001360:Avidin / Q000737:chemistry / Q000378:metabolism; D001710:Biotin / Q000737:chemistry / Q000378:metabolism; D045744:Cell Line, Tumor; D002470:Cell Survival / Q000187:drug effects; D004317:Doxorubicin / Q000737:chemistry / Q000633:toxicity; D004337:Drug Carriers / Q000737:chemistry*; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D016062:Porosity; D012822:Silicon Dioxide / Q000737:chemistry; D014815:Vitamins / Q000737:chemistry / Q000378:metabolism
chemical_list: D052157:Aptamers, Nucleotide; D004337:Drug Carriers; D014815:Vitamins; D001360:Avidin; D001710:Biotin; D012822:Silicon Dioxide; D004317:Doxorubicin