title: A semi-automated computer tool for the analysis of retinal vessel diameter dynamics.
abstract: Retinal vessels are directly accessible to clinical observation. This has numerous potential interests for medical investigations. Using the Retinal Vessel Analyzer, a dedicated eye fundus camera enabling dynamic, video-rate recording of micrometric changes of the diameter of retinal vessels, we developed a semi-automated computer tool that extracts the heart beat rate and pulse amplitude values from the records. The extracted data enabled us to show that there is a decreasing relationship between heart beat rate and pulse amplitude of arteries and veins. Such an approach will facilitate the modeling of hemodynamic interactions in small vessels.
authors.affiliation: Anagos, 55 rue des petites écuries, F75010 Paris, France. guillaume.euvrard@wanadoo.fr
authors.forename: Guillaume
authors.initials: G
authors.lastname: Euvrard
authors.forename: Olivier
authors.initials: O
authors.lastname: Genevois
authors.forename: Isabelle
authors.initials: I
authors.lastname: Rivals
authors.forename: Pascale
authors.initials: P
authors.lastname: Massin
authors.forename: Amélie
authors.initials: A
authors.lastname: Collet
authors.forename: José-Alain
authors.initials: JA
authors.lastname: Sahel
authors.forename: Michel
authors.initials: M
authors.lastname: Paques
mesh_terms: D000328:Adult; D016477:Artifacts; D003941:Diagnostic Techniques, Ophthalmological; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D016014:Linear Models; D012171:Retinal Vessels / Q000033:anatomy & histology* / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D014741:Video Recording