title: Polypropylene vs silicone Ahmed valve with adjunctive mitomycin C in paediatric age group: a prospective controlled study.
abstract: OBJECTIVE
  To compare the results of silicone and polypropylene Ahmed glaucoma valves (AGV) implanted during the first 10 years of life.
  
  
  METHODS
  A prospective study was performed on 50 eyes of 33 patients with paediatric glaucoma. Eyes were matched to either polypropylene or silicone AGV. In eyes with bilateral glaucoma, one eye was implanted with polypropylene and the other eye was implanted with silicone AGV.
  
  
  RESULTS
  Fifty eyes of 33 children were reviewed. Twenty five eyes received a polypropylene valve, and 25 eyes received a silicone valve. Eyes implanted with silicone valves achieved a significantly lower intraocular pressure (IOP) compared with the polypropylene group at 6 months, 1 year, and 2 years postoperatively. The average survival time was significantly longer (P=0.001 by the log-rank test) for the silicone group than for the polypropylene group and the cumulative probability of survival by the log-rank test at the end of the second year was 80% (SE: 8.0, 95% confidence interval (CI): 64-96%) in the silicone group and 56% (SE: 9.8, 95% CI: 40-90%) in the polypropylene group. The difference in the number of postoperative interventions and complications between both groups was statistically insignificant.
  
  
  CONCLUSIONS
  Silicone AGVs can achieve better IOP control, and longer survival with less antiglaucoma drops compared with polypropylene valves in children younger than 10 years.
authors.affiliation: Faculty of Medicine, Cairo University, Cairo, Egypt. yasminemelsayed@yahoo.com
authors.forename: Y
authors.initials: Y
authors.lastname: El Sayed
authors.forename: A
authors.initials: A
authors.lastname: Awadein
mesh_terms: D000477:Alkylating Agents / Q000008:administration & dosage; D000704:Analysis of Variance; D002648:Child; D002675:Child, Preschool; D005260:Female; D005901:Glaucoma / Q000601:surgery*; D020327:Glaucoma Drainage Implants; D006801:Humans; D007223:Infant; D007429:Intraocular Pressure; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage; D011126:Polypropylenes; D011446:Prospective Studies; D019919:Prosthesis Implantation; D012826:Silicone Elastomers
chemical_list: D000477:Alkylating Agents; D011126:Polypropylenes; D012826:Silicone Elastomers; D016685:Mitomycin