title: 1+1=3? The systematic development of a theoretical and evidence-based tailored multimedia intervention to improve medication adherence.
abstract: OBJECTIVE
  To describe the development of a theoretical and evidence-based tailored multimedia intervention to improve medication intake behavior in patients with inflammatory bowel disease (IBD). The intervention integrates interpersonal and technology-mediated strategies with the expectation that this will work synergistically.
  
  
  METHODS
  The development followed the Medical Research Council's framework. Three literature reviews and three pre-tests among 84 IBD patients and eight nurses were conducted to guide the development of the intervention. A feasibility study was carried out among four nurses and 29 patients.
  
  
  RESULTS
  The components include: (1) an online preparatory assessment (OPA); (2) tailored interpersonal communication; and (3) tailored text messaging. To support the development, the feasibility was tested. Results indicated that the OPA was comprehensive and could be a helpful tool for both patients and nurses to prepare for the consultation. The training was evaluated as being instructive and applicable with a mean mark of 8.5. Of the developed messages, 65.6% received positive evaluations and were used in the intervention.
  
  
  CONCLUSIONS
  By applying the framework, we were able to describe the logic behind the development of a tailored multimedia intervention to improve medication intake behavior.
  
  
  CONCLUSIONS
  This study could serve as a guide for the development of other health interventions.
authors.affiliation: Amsterdam School of Communication Research (ASCoR), University of Amsterdam, Amsterdam, The Netherlands. Electronic address: a.j.linn@uva.nl.
authors.forename: Annemiek J
authors.initials: AJ
authors.lastname: Linn
authors.forename: Julia C M
authors.initials: JC
authors.lastname: van Weert
authors.forename: Edith G
authors.initials: EG
authors.lastname: Smit
authors.forename: Kate
authors.initials: K
authors.lastname: Perry
authors.forename: Liset
authors.initials: L
authors.lastname: van Dijk
mesh_terms: D000328:Adult; D040421:Cell Phone; D003142:Communication; D019317:Evidence-Based Medicine; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy*; D007398:Interpersonal Relations; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D008962:Models, Theoretical; D019212:Multimedia; D017060:Patient Satisfaction; D016730:Program Development / Q000379:methods*; D060145:Text Messaging
keywords: Adherence; Beliefs about medication; Development; Interpersonal communication; Intervention; Medical Research Council's framework; Patient empowerment; Self-efficacy; Technology-mediated; eHealth