title: Gastroduodenal intussusception of a gastrointestinal stromal tumor (GIST): case report and review of the literature.
abstract: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors in adults. They frequently occur in the stomach. Gastric GISTs typically present as a gastrointestinal bleed but can sometimes cause obstructive symptoms such as nausea and vomiting. We present a patient with a gastric GIST and liver metastases who during treatment with iminitab therapy presented with an acute gastric outlet obstruction. A computed tomography scan revealed a gastroduodenal intussusception of the gastric GIST. The patient underwent a laparoscopic exploration and resection of the GIST. We reviewed the English language literature of GISTs that presented as a gastroduodenal intussusception and put our case in the context of the previously reported cases. We discuss the diagnostic and therapeutic challenges that arise when treating these patients.
authors.affiliation: Department of Surgery, Thomas Jefferson University, Philadelphia, PA 19107, USA.
authors.forename: David W
authors.initials: DW
authors.lastname: Rittenhouse
authors.forename: Pei-Wen
authors.initials: PW
authors.lastname: Lim
authors.forename: Lawrence A
authors.initials: LA
authors.lastname: Shirley
authors.forename: Karen A
authors.initials: KA
authors.lastname: Chojnacki
mesh_terms: D004378:Duodenal Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D017219:Gastric Outlet Obstruction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery*; D046152:Gastrointestinal Stromal Tumors / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D007443:Intussusception / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D010535:Laparoscopy / Q000379:methods; D008875:Middle Aged; D018570:Risk Assessment; D013272:Stomach Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery; D013274:Stomach Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome