title: Granulocytic sarcoma in breast after bone marrow transplantation.
abstract: Granulocytic sarcoma is a localized extramedullary solid tumor composed of immature myeloid cell and is usually associated with acute myeloid leukemia or myelodysplastic syndrome. Although it can involve any site, commonly in lymph nodes, skin, bone and soft tissue, the involvement of breast is unusual. Especially, the involvement of the breast as a pattern of relapse after bone marrow transplantation is extremely rare. We have experienced 2 cases of granulocytic sarcoma after bone marrow transplantation. One case was a 39-year-old woman with right breast mass diagnosed with granulocytic sarcoma. She had received an unrelated bone marrow transplantation due to biphenotype acute leukemia 3 years before our presentation. Another case was a 48-year-old woman with acute myeloid leukemia, who was diagnosed with granulocytic sarcoma on both breasts 8 months after allogenic bone marrow transplantation. We also discuss the clinicopathologic features of granulocytic sarcoma in breast after bone marrow transplantation.
authors.affiliation: Special Study Module for Breast, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Seung Jin
authors.initials: SJ
authors.lastname: Kim
authors.forename: Woo Sung
authors.initials: WS
authors.lastname: Hong
authors.forename: Sung Hyun
authors.initials: SH
authors.lastname: Jun
authors.forename: Seong Hyun
authors.initials: SH
authors.lastname: Jeong
authors.forename: Seok Youn
authors.initials: SY
authors.lastname: Kang
authors.forename: Tae Hee
authors.initials: TH
authors.lastname: Kim
authors.forename: Doo Kyoung
authors.initials: DK
authors.lastname: Kang
authors.forename: Hyun Ee
authors.initials: HE
authors.lastname: Yim
authors.forename: Yong Sik
authors.initials: YS
authors.lastname: Jung
authors.forename: Ku Sang
authors.initials: KS
authors.lastname: Kim
keywords: Acute myeloid leukemia; Breast; Granulocytic sarcoma