title: [Faecal occult blood test for colorectal cancer screening: high quality for a good price].
abstract: The Dutch National Institute for Public Health and the Environment (RIVM) awarded the immunochemical faecal occult blood test (IFOBT) to FOB Gold of Sentinel following a European call for tenders. The contract-awarding procedure included the application of quality knock-out criteria, which were met by two suppliers. The decisive factor was the best price/quality ratio. A recent review indicated that, at present, no single IFOBT is better than any other. The decision to opt for a test manufactured by a different supplier than was used in the previous screening pilots made it necessary to re-determine the cut-off value. This value has now been set (88 ng/ml) and is confirmed by a laboratory test. Colonoscopy-related capacity planning, as well as its diagnostic yield, depends on numerous factors; therefore, the RIVM is currently monitoring the referral percentage and number of adenomas detected and is collaborating on quality terms. Any necessary adjustments are to be made during the introduction of the screening test.
authors.affiliation: Rijksinstituut voor Volksgezondheid en Milieu, Centrum voor Bevolkingsonderzoek, Bilthoven, the Netherlands. harriet.van.veldhuizen@rivm.nl
authors.forename: Harriët
authors.initials: H
authors.lastname: van Veldhuizen
authors.forename: J M G Hans
authors.initials: JM
authors.lastname: Bonfrer
authors.forename: Ernst J
authors.initials: EJ
authors.lastname: Kuipers
mesh_terms: D000236:Adenoma / Q000175:diagnosis / Q000191:economics / Q000517:prevention & control; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000191:economics / Q000517:prevention & control; D003362:Cost-Benefit Analysis; D055088:Early Detection of Cancer / Q000191:economics* / Q000592:standards*; D006801:Humans; D008403:Mass Screening / Q000379:methods; D009780:Occult Blood