title: Growth Inhibitory Activity of a Bis-benzimidazole-Bridged Arene Ruthenium Metalla-Rectangle and Prism.
abstract: Two new supramolecular coordination complexes (SCCs), were obtained from the self-assembly of a new bis-benzimidazole bridged Ru acceptor,4, with dipyridyl and tripyridyl donors, respectively. As part of a growing library of anticancer-active Ru-based SCCs, metalla-prism6selectively showed high cytotoxicities relative to cisplatin for a series of cancer cell lines, with IC50values as low as 8.41 μM for MCF7 cells, as determined from MTS assays.
authors.affiliation: Department of Chemistry, University of Ulsan, Ulsan 680-749, Republic of Korea.
authors.forename: Vaishali
authors.initials: V
authors.lastname: Vajpayee
authors.forename: Sun Mi
authors.initials: SM
authors.lastname: Lee
authors.forename: Joeng Woo
authors.initials: JW
authors.lastname: Park
authors.forename: Abhishek
authors.initials: A
authors.lastname: Dubey
authors.forename: Hyunuk
authors.initials: H
authors.lastname: Kim
authors.forename: Timothy R
authors.initials: TR
authors.lastname: Cook
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Stang
authors.forename: Ki-Whan
authors.initials: KW
authors.lastname: Chi