title: [T-cell prolymphocytic leukemia revealed by spinal cord compression].
abstract: T-cell prolymphocytic leukemia is a lymphoid hematologic malignancy of T origin, mature, individualized well by the clinical, morphological, and immunophenotypic as well as cytogenetic aspects. We report the case of a 39-year-old man admitted in our department because of a spinal cord compression. The cerebrospinal fluid analysis had revealed an increased albuminemia level; MRI evoked a vertebral infiltration by a malignancy. Evolution was characterized by the appearance of a tumor syndrome and a peripheral lymphocytosis. Immunophenotyping and the lymph node biopsy concluded of a diagnosis of a T-cell prolymphocytic leukemia. To our knowledge, we report here the first case of T-cell prolymphocytic leukemia revealed by a spinal cord compression.
authors.affiliation: Service d'hématologie, CHU Mohamed VI, Université Cadi Ayyad, Marrakech, Morocco. khalilhaouach@yahoo.fr
authors.forename: Khalil
authors.initials: K
authors.lastname: Haouach
authors.forename: Ilias
authors.initials: I
authors.lastname: Tazi
authors.forename: Lahoussin
authors.initials: L
authors.lastname: Mahmal
mesh_terms: D000328:Adult; D002555:Cerebrospinal Fluid / Q000166:cytology; D003937:Diagnosis, Differential; D006801:Humans; D015461:Leukemia, Prolymphocytic, T-Cell / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D013117:Spinal Cord Compression / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology
keywords: chemotherapy; leukemia; prolymphocyte; spinal cord compression