title: Increased prevalence of psychotic disorders among third-generation migrants: results from the French Mental Health in General Population survey.
abstract: There is very strong evidence that the prevalence of psychosis is elevated in migrant populations and that this risk persists into the second generation. However, these results have not been replicated in France, and the prevalence of psychotic disorders in the third generation of migrants remains unknown. Based on the Mental Health in General Population survey (n=37063), we report for the first time the increased prevalence of psychotic disorders in migrants in France, which persists into the second generation for a single psychotic episode (SPE) (OR=1.43, 95% CI [1.02-2.03], p<0.03) and into the third generation for recurrent psychotic disorder (RPD) (OR=1.78, 95% CI [1.45-2.18], p<0.0001) after adjustment for age, sex, level of education and cannabis use. Complementary statistical analyses of our sample showed a significantly higher risk of SPE in migrants from the French West Indies and Africa (χ(2)=17.70, p<0.01). These results are consistent with the socio-developmental model and the psychosis continuum hypothesis.
authors.affiliation: Univ Lille Nord de France, CHRU de Lille, F-59000 Lille, France; Psychiatry Department, University Medical Centre of Lille (CHULille), F-59037 Lille, France; Laboratoire de Neurosciences Fonctionnelles et Pathologies (LNFP), Universite "Droit & Sante" Lille (UDSL), Lille, France. Electronic address: ali.amad@chru-lille.fr.
authors.forename: Ali
authors.initials: A
authors.lastname: Amad
authors.affiliation: Univ Lille Nord de France, CHRU de Lille, F-59000 Lille, France; Psychiatry Department, University Medical Centre of Lille (CHULille), F-59037 Lille, France; Laboratoire de Neurosciences Fonctionnelles et Pathologies (LNFP), Universite "Droit & Sante" Lille (UDSL), Lille, France; Addiction Department, CHU Lille, F-59000 Lille, France.
authors.forename: Dewi
authors.initials: D
authors.lastname: Guardia
authors.affiliation: Univ Lille Nord de France, CHRU de Lille, F-59000 Lille, France; Department of Biostatistics, CHULille, F-59000 Lille, France.
authors.forename: Julia
authors.initials: J
authors.lastname: Salleron
authors.affiliation: Univ Lille Nord de France, CHRU de Lille, F-59000 Lille, France; Psychiatry Department, University Medical Centre of Lille (CHULille), F-59037 Lille, France; Laboratoire de Neurosciences Fonctionnelles et Pathologies (LNFP), Universite "Droit & Sante" Lille (UDSL), Lille, France; Fédération régionale de recherche en santé mentale (F2RSM) Nord - Pas-de-Calais, Lille, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Thomas
authors.affiliation: World Health Organization Collaborative Centre (WHO-CC), EPSM Lille-Metropole, Lille, France.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Roelandt
authors.affiliation: Univ Lille Nord de France, CHRU de Lille, F-59000 Lille, France; Psychiatry Department, University Medical Centre of Lille (CHULille), F-59037 Lille, France; Laboratoire de Neurosciences Fonctionnelles et Pathologies (LNFP), Universite "Droit & Sante" Lille (UDSL), Lille, France; Fédération régionale de recherche en santé mentale (F2RSM) Nord - Pas-de-Calais, Lille, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Vaiva
mesh_terms: D000328:Adult; D016009:Chi-Square Distribution; D018672:Community Health Planning; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D015995:Prevalence; D011618:Psychotic Disorders / Q000453:epidemiology*; D012189:Retrospective Studies; D014171:Transients and Migrants / Q000523:psychology; D055815:Young Adult