title: Association between cerebral lesions and emotional changes in acute ischemic stroke patients.
abstract: Controversies and interest are present in the associations between specific brain locations and depression or anxiety. This study investigated the association between stroke location and emotional changes in stroke patients. This prospective observational study analyzed the neuroimages and neuropsychiatric conditions of 26 patients with acute middle cerebral artery infarction. Each patient's neurological and psychiatric condition was evaluated 1 week as well as 1 month after the stroke. We found that the right superior and middle temporal gyrus was associated with anxiety at 1 month after stroke. Moreover, better mentality is associated with deterioration of anxiety within 1 month after stroke, and larger lesion volume is associated with deterioration of depression within 1 month after stroke.
authors.affiliation: Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan.
authors.forename: Hsiao-Lun
authors.initials: HL
authors.lastname: Ku
authors.forename: Chia-Hui
authors.initials: CH
authors.lastname: Chen
authors.forename: Ya-Ting
authors.initials: YT
authors.lastname: Yang
authors.forename: Chaur-Jong
authors.initials: CJ
authors.lastname: Hu
authors.forename: Dean
authors.initials: D
authors.lastname: Wu
authors.forename: Chih-Chung
authors.initials: CC
authors.lastname: Chen
authors.forename: Po-Chih
authors.initials: PC
authors.lastname: Chen
authors.forename: Nai-Fang
authors.initials: NF
authors.lastname: Chi
mesh_terms: D000368:Aged; D001007:Anxiety / Q000209:etiology* / Q000473:pathology; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology*; D002544:Cerebral Infarction / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D003863:Depression / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D059906:Neuroimaging; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index; D013702:Temporal Lobe / Q000473:pathology; D013997:Time Factors; D014057:Tomography, X-Ray Computed