title: Efficacy of nasal irrigations and nebulizations for nasal symptom relief.
abstract: OBJECTIVE
  To review current literature regarding the use and utility of nasal saline irrigation in nasal and sinus diseases.
  
  
  RESULTS
  Nasal irrigations, in various forms, are a widely used and accepted means of treatment of the symptoms of chronic rhinosinusitis and other sinonasal disease processes. Over the past two decades, significant research has been done to evaluate the role of nasal irrigations in the treatment of sinonasal disease. The use of a high-volume, low-pressure system like a squeeze bottle remains the optimal delivery device. Although additional research is required for many of the additives discussed, the use of xylitol in chronic rhinosinusitis and topical fluconazole in allergic fungal sinusitis appear promising.
  
  
  CONCLUSIONS
  Use of nasal saline irrigations can improve symptoms of sinonasal disease and may improve outcomes in certain settings. Ongoing research will continue to shape and optimize understanding of maximally effective nasal irrigations.
authors.affiliation: Otolaryngology Service, San Antonio Military Medical Center, San Antonio, Texas 78229, USA.
authors.forename: Joel D
authors.initials: JD
authors.lastname: Dunn
authors.forename: Gregory R
authors.initials: GR
authors.lastname: Dion
authors.forename: Kevin C
authors.initials: KC
authors.lastname: McMains
mesh_terms: D006801:Humans; D055556:Nasal Lavage / Q000295:instrumentation / Q000379:methods; D009330:Nebulizers and Vaporizers; D012221:Rhinitis, Allergic, Perennial / Q000628:therapy*; D006255:Rhinitis, Allergic, Seasonal / Q000628:therapy*; D012852:Sinusitis / Q000628:therapy*; D012965:Sodium Chloride
chemical_list: D012965:Sodium Chloride