title: Quantitative microfluidic biomolecular analysis for systems biology and medicine.
abstract: In the postgenome era, biology and medicine are rapidly evolving towards quantitative and systems studies of complex biological systems. Emerging breakthroughs in microfluidic technologies and innovative applications are transforming systems biology by offering new capabilities to address the challenges in many areas, such as single-cell genomics, gene regulation networks, and pathology. In this review, we focus on recent progress in microfluidic technology from the perspective of its applications to promoting quantitative and systems biomolecular analysis in biology and medicine.
authors.affiliation: Department of Chemistry and Ralph N Adams Institute of Bioanalytical Chemistry, University of Kansas, Lawrence, KS 66045, USA. yongz@ku.edu
authors.forename: Yong
authors.initials: Y
authors.lastname: Zeng
authors.forename: Tanyu
authors.initials: T
authors.lastname: Wang
mesh_terms: D000818:Animals; D003933:Diagnosis; D053263:Gene Regulatory Networks; D023281:Genomics; D006801:Humans; D008511:Medicine / Q000295:instrumentation / Q000379:methods*; D046210:Microfluidic Analytical Techniques / Q000295:instrumentation / Q000379:methods*; D049490:Systems Biology / Q000295:instrumentation / Q000379:methods*