title: Multidisciplinary approach to a Marfan syndrome patient with emphasis on cardiovascular complications.
abstract: BACKGROUND
  Marfan syndrome (MFS) is the most common inherited disorder of connective tissue affecting multiple organ systems. The most life-threatening and life-shortening complication is aortic dissection. Without surgery, life expectancy of MFS patients is reduced to approximately 32 years. Early identification and appropriate multidisciplinary medical cooperation is essential.
  
  
  CONCLUSIONS
  Proper follow up, therapy and timely surgical repair lead to an almost normal lifespan in affected individuals.
authors.affiliation: Department of Cardiac Surgery, University Hospital Olomouc, Czech Republic. petr.santavy@fnol.cz
authors.forename: Petr
authors.initials: P
authors.lastname: Santavy
mesh_terms: D000784:Aortic Dissection / Q000175:diagnosis / Q000235:genetics; D001014:Aortic Aneurysm / Q000175:diagnosis / Q000235:genetics; D002318:Cardiovascular Diseases / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics* / Q000601:surgery; D013504:Cardiovascular Surgical Procedures / Q000379:methods; D005500:Follow-Up Studies; D005817:Genetic Counseling; D006801:Humans; D008017:Life Expectancy; D008382:Marfan Syndrome / Q000150:complications / Q000235:genetics*; D011788:Quality of Life; D016896:Treatment Outcome