title: Thrombocytosis as a potential cause of a very late stent thrombosis in the left main coronary artery.
abstract: A 36 year-old man, who had undergone a paclitaxel-eluting stent deployment into the left main (LM) coronary artery three years before, was admitted after successful resuscitation following out-of-hospital cardiac arrest due to an acute ST-segment elevation myocardial infarction. Six weeks before the admission, he had discontinued clopidogrel. Coronary angiography showed a total occlusion of the LM artery. A complex percutaneous coronary intervention including thrombectomy and a second everolimus-eluting stent deployment in the LM artery and the left descending coronary artery was performed; this resulted in the restoration of TIMI 2/3 flow. A detailed investigation revealed an essential thrombocytosis necessitating treatment with hydroxyurea and indefinite dual antiplatelet therapy.
authors.affiliation: mmprech@wp.pl
authors.forename: Marek
authors.initials: M
authors.lastname: Prech
authors.forename: Magdalena
authors.initials: M
authors.lastname: Janus
authors.forename: Konrad
authors.initials: K
authors.lastname: Lukawski
authors.forename: Maciej
authors.initials: M
authors.lastname: Lesiak
mesh_terms: D000328:Adult; D000077144:Clopidogrel; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000000981:diagnostic imaging / Q000209:etiology; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology*; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy; D058687:Out-of-Hospital Cardiac Arrest / Q000209:etiology / Q000628:therapy; D017239:Paclitaxel / Q000008:administration & dosage; D013922:Thrombocytosis / Q000188:drug therapy / Q000209:etiology*; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D028761:Withholding Treatment
chemical_list: D000077144:Clopidogrel; D013988:Ticlopidine; D017239:Paclitaxel