title: A turn-on fluorescent probe for detection of tyrosinase activity.
abstract: We have presented a fluorescent probe that exhibits a fluorescence turn-on signal upon reaction with tyrosinase, and we show that it can be readily employed for the assessment of tyrosinase activity and tyrosinase inhibitor activities in buffered aqueous solution.
authors.affiliation: College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, Hubei 430072, P. R. China.
authors.forename: Changcheng
authors.initials: C
authors.lastname: Wang
authors.forename: Shengyong
authors.initials: S
authors.lastname: Yan
authors.forename: Rong
authors.initials: R
authors.lastname: Huang
authors.forename: Shuo
authors.initials: S
authors.lastname: Feng
authors.forename: Boshi
authors.initials: B
authors.lastname: Fu
authors.forename: Xiaocheng
authors.initials: X
authors.lastname: Weng
authors.forename: Xiang
authors.initials: X
authors.lastname: Zhou
mesh_terms: D001547:Benzaldehydes / Q000737:chemistry / Q000494:pharmacology; D019817:Benzoic Acid / Q000737:chemistry / Q000494:pharmacology; D004789:Enzyme Activation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D014442:Monophenol Monooxygenase / Q000032:analysis* / Q000037:antagonists & inhibitors / Q000378:metabolism; D010069:Oxadiazoles / Q000737:chemistry*; D013329:Structure-Activity Relationship
chemical_list: D001547:Benzaldehydes; D004791:Enzyme Inhibitors; D005456:Fluorescent Dyes; D010069:Oxadiazoles; D019817:Benzoic Acid; D014442:Monophenol Monooxygenase; C032175:benzaldehyde