title: The characterization of childhood occipital epilepsy of Gastaut: a study of seven patients.
abstract: Characterization of the electroclinical features and evolution of childhood occipital epilepsy of Gastaut (COE-G). Seven children were retrospectively identified as having COE-G and were followed-up clinically using EEGs. Visual manifestations were the most common ictal event. Eye-associated ictal deviation was associated with ipsilateral turning of the head and migraine-like symptoms were frequent. Hemiconvulsions occurred in two children, and only one child had secondary generalized tonic-clonic seizures. In all patients, seizures occurred while awake, while two patients also had seizures while sleeping. EEG showed five patients with occipital spike-wave discharges when their eyes were closed which disappeared once their eyes were opened. Two cases continued having frequent seizures despite antiepileptic drug treatment. These patients also displayed learning difficulties and behavioral impairments after seizure onset. COE-G is a distinctive epileptic syndrome; however, the long-term prognosis for patients with the condition is unclear.
authors.affiliation: Department of Pediatrics, The First Affiliated Hospital of Zunyi Medical College, 149 Dalian Road, Zunyi, 563003, Guzhou, China, shuxiaomei1993@sina.com.
authors.forename: Xiao Mei
authors.initials: XM
authors.lastname: Shu
authors.forename: Gui Ping
authors.initials: GP
authors.lastname: Zhang
authors.forename: Bing Zhu
authors.initials: BZ
authors.lastname: Yang
authors.forename: Juan
authors.initials: J
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use; D001921:Brain / Q000000981:diagnostic imaging; D002648:Child; D002653:Child Behavior Disorders / Q000209:etiology; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008881:Migraine Disorders / Q000175:diagnosis; D012189:Retrospective Studies; D003294:Seizures, Febrile / Q000175:diagnosis; D014057:Tomography, X-Ray Computed
chemical_list: D000927:Anticonvulsants