title: [Studies on spray of niclosamide ethanolamine salt II observation on prevention of Schistosoma japonicum infection in bovine].
abstract: OBJECTIVE
  To investigate the spray of niclosamide ethanolamine salt on prevention of bovine schistosomiasis in the field so as to provide a technical support for the improvement of schistosomiasis control strategy.
  
  
  METHODS
  A total of 160 buffalo were selected as experimental objects marked by ear-mark numbers. All the buffalo were administered with praziquantel and then randomly divided into 3 groups, which were sprayed with niclosamide ethanolamine salt (500 ml per head) every 15 d (Group A), every 30 d (Group B) and an agent without niclosamide ethanolamine salt every 15 d (Group C as the control), respectively. The buffalo's droppings were collected to examine the eggs of schistosome every 30 days during the trial.
  
  
  RESULTS
  Ninety days after the spraying, the prevalence rates of schistosomiasis were 4.00%, 4.08%, and 24.49% in the Group A, Group B, and Group C, respectively. Compared with the control group (Group C), the decline prevalence rates of schistosomiasis were 83.67% and 83.34% in the Group A and Group B, respectively.
  
  
  CONCLUSIONS
  The buffalo spraying with 1% niclosamide ethanolamine salt can reduce schistosomiasis prevalence in bovine, that is this intervention has an obvious protective effect.
authors.affiliation: Jiangsu Institute of Parasitic Diseases, Key Laboratory on Technology for Parasitic Disease Prevention and Control, Ministry of Health, Center for Pesticide Effect Evaluation, Ministry of Agriculture, Wuxi 214064, China.
authors.forename: Jian-Rong
authors.initials: JR
authors.lastname: Dai
authors.forename: Yun-Tian
authors.initials: YT
authors.lastname: Xing
authors.forename: Hong-Jun
authors.initials: HJ
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Yong-Hui
authors.initials: YH
authors.lastname: Tao
authors.forename: An
authors.initials: A
authors.lastname: Ning
authors.forename: Zu-Lu
authors.initials: ZL
authors.lastname: Gao
authors.forename: You-Cai
authors.initials: YC
authors.lastname: Wu
authors.forename: Mei-Long
authors.initials: ML
authors.lastname: Wang
authors.forename: You-Sheng
authors.initials: YS
authors.lastname: Liang
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000008:administration & dosage*; D002417:Cattle; D002418:Cattle Diseases / Q000517:prevention & control*; D019856:Ethanolamine / Q000008:administration & dosage*; D009534:Niclosamide / Q000008:administration & dosage*; D012492:Salts / Q000008:administration & dosage; D012554:Schistosomiasis japonica / Q000517:prevention & control / Q000662:veterinary*
chemical_list: D000969:Antinematodal Agents; D012492:Salts; D019856:Ethanolamine; D009534:Niclosamide