title: A 40-year-old male with an intraventricular tumor. Combined tanycytic ependymoma and subependymoma.
abstract: Combined tumors showing histologic features of both ependymoma and subependymoma have been described. In this report we present a case of combined tanycytic ependymoma with foci of subependymoma (WHO grade II), occurring in a 40 year-old male, which arose in the wall of the lateral ventricle. The tanycytic ependymoma component showed elongated fibrillary cells with a fascicular pattern of growth, while the subependymoma component showed clustered cell bodies surrounded by a fibrillary stroma with a microcystic appearance.We consider the present case to be an unusual example of tanycytic ependymoma; which to the best of our knowledge has not been associated with a subependymoma.
authors.affiliation: Department of Pathology, Rush University Medical Center, Chicago, IL, USA.
authors.forename: Leonidas D
authors.initials: LD
authors.lastname: Arvanitis
authors.forename: Paolo
authors.initials: P
authors.lastname: Gattuso
authors.forename: Sukriti
authors.initials: S
authors.lastname: Nag
mesh_terms: D000328:Adult; D002551:Cerebral Ventricle Neoplasms / Q000473:pathology* / Q000601:surgery; D004396:Coloring Agents; D004806:Ependymoma / Q000473:pathology* / Q000601:surgery; D018315:Glioma, Subependymal / Q000473:pathology* / Q000601:surgery; D006801:Humans; D019394:Ki-67 Antigen; D008279:Magnetic Resonance Imaging; D008297:Male; D019635:Neurosurgical Procedures; D016896:Treatment Outcome
chemical_list: D004396:Coloring Agents; D019394:Ki-67 Antigen