title: Preoperative neutrophil-lymphocyte ratio and saphenous vein graft patency after coronary artery bypass grafting.
abstract: OBJECTIVE
  The aim of the present study was to investigate the predictive value of preoperative neutrophil-lymphocyte ratio (NLR) in postoperative saphenous vein graft patency in patients undergoing coronary artery bypass grafting (CABG) surgery.
  
  
  METHODS
  We retrospectively analyzed 444 patients who had undergone CABG and a further control coronary angiography due to recurrence of symptoms. The patients were divided into tertile groups according to the NLR. The primary end point was 50% saphenous vein graft stenosis or more or complete occlusion.
  
  
  RESULTS
  The saphenous vein graft failure in the 3 groups based on NLR was 33%, 66.2%, and 79.1%, in the low-, middle- and high-risk groups, respectively. In multivariate regression modeling, current smoker, diabetes mellitus, target artery diameter <1.5 mm, and NLR independently predicted saphenous vein graft patency in patients after CABG.
  
  
  CONCLUSIONS
  Preoperative NLR is clearly an independent predictor of saphenous vein graft patency in patients after CABG.
authors.affiliation: Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart Education and Research Hospital, Ankara, Turkey irfantasoglu@yahoo.com.
authors.forename: Irfan
authors.initials: I
authors.lastname: Taşoğlu
authors.affiliation: Department of Cardiology, Turkiye Yuksek Ihtisas Heart, Education and Research Hospital, Ankara, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Turak
authors.affiliation: Department of Cardiovascular Surgery, Fatih Unıversty Medical Faculty, Ankara, Turkey.
authors.forename: Yunus
authors.initials: Y
authors.lastname: Nazli
authors.affiliation: Department of Cardiology, Turkiye Yuksek Ihtisas Heart, Education and Research Hospital, Ankara, Turkey.
authors.forename: Fırat
authors.initials: F
authors.lastname: Ozcan
authors.affiliation: Department of Cardiovascular Surgery, Fatih Unıversty Medical Faculty, Ankara, Turkey.
authors.forename: Necmettin
authors.initials: N
authors.lastname: Colak
authors.affiliation: Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart Education and Research Hospital, Ankara, Turkey.
authors.forename: Serpil
authors.initials: S
authors.lastname: Sahin
authors.affiliation: Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart Education and Research Hospital, Ankara, Turkey.
authors.forename: Kemal
authors.initials: K
authors.lastname: Kavasoglu
authors.affiliation: Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart Education and Research Hospital, Ankara, Turkey.
authors.forename: Bahadır
authors.initials: B
authors.lastname: Genc
authors.affiliation: Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart Education and Research Hospital, Ankara, Turkey.
authors.forename: Doğan
authors.initials: D
authors.lastname: Sert
authors.affiliation: Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart Education and Research Hospital, Ankara, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Karahan
authors.affiliation: Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart Education and Research Hospital, Ankara, Turkey.
authors.forename: Omer
authors.initials: O
authors.lastname: Cicek
authors.affiliation: Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Heart Education and Research Hospital, Ankara, Turkey.
authors.forename: Ata
authors.initials: A
authors.lastname: Ecevit
mesh_terms: D000328:Adult; D000368:Aged; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D003324:Coronary Artery Disease / Q000097:blood / Q000601:surgery*; D005260:Female; D006083:Graft Occlusion, Vascular / Q000097:blood / Q000209:etiology*; D006801:Humans; D007958:Leukocyte Count; D016015:Logistic Models; D008214:Lymphocytes; D008297:Male; D008875:Middle Aged; D009504:Neutrophils; D011182:Postoperative Care; D012189:Retrospective Studies; D012501:Saphenous Vein / Q000637:transplantation*
keywords: anticoagulants; atherosclerosis; thrombosis; vascular disease