title: Transmitted drug resistance in French HIV-2-infected patients.
abstract: We report the first transmitted drug resistance survey study in HIV-2-infected patients living in France. The prevalence of transmitted drug resistance was 5.0% (95% confidence interval, 0.1-9.9) with mutations detected only in protease, not in reverse transcriptase. In this series, 10% of patients displayed X4/dual-mixed viruses. These findings classified the rate of transmitted drug resistance in the HIV-2 French Cohort as low prevalence.
authors.affiliation: Laboratoire de Virologie, Assistance Publique-Hôpitaux de Paris (AP-HP), Groupe Hospitalier Bichat-Claude Bernard, HUPNVS, Université Paris Diderot, Paris 7, PRES Sorbonne Paris Cité, Paris, France. charlotte.charpentier@bch.aphp.fr
authors.forename: Charlotte
authors.initials: C
authors.lastname: Charpentier
authors.forename: Benoit
authors.initials: B
authors.lastname: Visseaux
authors.forename: Antoine
authors.initials: A
authors.lastname: Bénard
authors.forename: Gilles
authors.initials: G
authors.lastname: Peytavin
authors.forename: Florence
authors.initials: F
authors.lastname: Damond
authors.forename: Céline
authors.initials: C
authors.lastname: Roy
authors.forename: Audrey
authors.initials: A
authors.lastname: Taieb
authors.forename: Geneviève
authors.initials: G
authors.lastname: Chêne
authors.forename: Sophie
authors.initials: S
authors.lastname: Matheron
authors.forename: Françoise
authors.initials: F
authors.lastname: Brun-Vézinet
authors.forename: Diane
authors.initials: D
authors.lastname: Descamps
mesh_terms: D024882:Drug Resistance, Viral / Q000235:genetics*; D005602:France / Q000453:epidemiology; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology / Q000821:virology*; D017320:HIV Protease Inhibitors / Q000494:pharmacology; D015498:HIV-2 / Q000187:drug effects / Q000235:genetics*; D006801:Humans; D015995:Prevalence; D012367:RNA, Viral / Q000235:genetics; D018894:Reverse Transcriptase Inhibitors / Q000494:pharmacology
chemical_list: D017320:HIV Protease Inhibitors; D012367:RNA, Viral; D018894:Reverse Transcriptase Inhibitors