title: Cohort profile of the Japan Collaborative Cohort Study at final follow-up.
abstract: The Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study) was established in the late 1980s to evaluate the risk impact of lifestyle factors and levels of serum components on human health. During the 20-year follow-up period, the results of the study have been published in almost 200 original articles in peer-reviewed English-language journals. However, continued follow-up of the study subjects became difficult because of the retirements of principal researchers, city mergers throughout Japan in the year 2000, and reduced funding. Thus, we decided to terminate the JACC Study follow-up at the end of 2009. As a final point of interest, we reviewed the population registry information of survivors. A total of 207 (0.19%) subjects were ineligible, leaving 110 585 eligible participants (46 395 men and 64 190 women). Moreover, errors in coding date of birth and sex were found in 356 (0.32%) and 59 (0.05%) cases, respectively, during routine follow-up and final review. Although such errors were unexpected, their impact is believed to be negligible because of the small numbers relative to the large total study population. Here, we describe the final cohort profile at the end of the JACC Study along with selected characteristics of the participants and their status at the final follow-up. Although follow-up of the JACC Study participants is finished, we will continue to analyze and publish study results.
authors.affiliation: Department of Public Health, Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan. tamaa@med.hokudai.ac.jp
authors.forename: Akiko
authors.initials: A
authors.lastname: Tamakoshi
authors.forename: Kotaro
authors.initials: K
authors.lastname: Ozasa
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Fujino
authors.forename: Koji
authors.initials: K
authors.lastname: Suzuki
authors.forename: Kiyomi
authors.initials: K
authors.lastname: Sakata
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Mori
authors.forename: Shogo
authors.initials: S
authors.lastname: Kikuchi
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Iso
authors.forename: Fumio
authors.initials: F
authors.lastname: Sakauchi
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Motohashi
authors.forename: Ichiro
authors.initials: I
authors.lastname: Tsuji
authors.forename: Yosikazu
authors.initials: Y
authors.lastname: Nakamura
authors.forename: Haruo
authors.initials: H
authors.lastname: Mikami
authors.forename: Michiko
authors.initials: M
authors.lastname: Kurosawa
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Hoshiyama
authors.forename: Naohito
authors.initials: N
authors.lastname: Tanabe
authors.forename: Koji
authors.initials: K
authors.lastname: Tamakoshi
authors.forename: Kenji
authors.initials: K
authors.lastname: Wakai
authors.forename: Shinkan
authors.initials: S
authors.lastname: Tokudome
authors.forename: Shuji
authors.initials: S
authors.lastname: Hashimoto
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Wada
authors.forename: Takashi
authors.initials: T
authors.lastname: Kawamura
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Watanabe
authors.forename: Tsuneharu
authors.initials: T
authors.lastname: Miki
authors.forename: Chigusa
authors.initials: C
authors.lastname: Date
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Kurozawa
authors.forename: Takesumi
authors.initials: T
authors.lastname: Yoshimura
authors.forename: Akira
authors.initials: A
authors.lastname: Shibata
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Okamoto
authors.forename: Hideo
authors.initials: H
authors.lastname: Shio
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D002423:Cause of Death; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology*; D012042:Registries; D017678:Sex Distribution