title: [PREFERE - the German prostatic cancer study: questions and claims surrounding study initiation in January 2013].
abstract: The PREFERE study is a multicenter randomized study of patients with low or early intermediate risk for prostatic cancer. The four treatment options, radical prostatectomy, percutaneous irradiation therapy, permanent seed implantation and active surveillance recommended by the German S3 guidelines and international guidelines will be tested and compared with respect to effectiveness and potential side effects. Over a period of 4 years a total of 7,600 patients are to be recruited and assigned to 1 of these 4 therapy forms according to personal preference (by possible exclusion of 1 or 2 therapy options) in a 2-4 arm study design by randomization.
authors.affiliation: Klinik für Strahlentherapie und Radioonkologie, Universitätsklinikum Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Deutschland. Thomas.Wiegel@uniklinik-ulm.de
authors.forename: T
authors.initials: T
authors.lastname: Wiegel
authors.forename: P
authors.initials: P
authors.lastname: Albers
authors.forename: R
authors.initials: R
authors.lastname: Bussar-Maatz
authors.forename: A
authors.initials: A
authors.lastname: Gottberg
authors.forename: M
authors.initials: M
authors.lastname: Härter
authors.forename: M
authors.initials: M
authors.lastname: Kieser
authors.forename: G
authors.initials: G
authors.lastname: Kristiansen
authors.forename: G
authors.initials: G
authors.lastname: Nettekoven
authors.forename: P
authors.initials: P
authors.lastname: Martus
authors.forename: H
authors.initials: H
authors.lastname: Schmidberger
authors.forename: S
authors.initials: S
authors.lastname: Wellek
authors.forename: M
authors.initials: M
authors.lastname: Stöckle
mesh_terms: D001918:Brachytherapy / Q000706:statistics & numerical data*; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008297:Male; D015995:Prevalence; D011468:Prostatectomy / Q000706:statistics & numerical data*; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*; D020266:Radiotherapy, Conformal / Q000706:statistics & numerical data*; D016896:Treatment Outcome