title: [Placental chorangioma: clinic-pathological approach of a case in Colombia].
abstract: Chorangioma is a tumor of vascular origin placental, the most frequent among primary placental non-trophoblastic tumors; however, it is found in about 1% of placental pathology case studies. Chorangioma represents a benign neoplasm with proliferation of capillaries and villous stroma associated to multiple gestations, preeclampsia and birth defects in the fetus. This paper reports the case of a 38-year pregnant woman (29 gestation weeks). She had eleven pregnancies, nine deliveries and one abortion. During perinatal assessment patient showed severe polyhydramnios and acute fetal distress. The histopathologic examination of the placenta showed a mass with hemorrhagic areas. The microscopic examination revealed proliferation of small fetal capillary vessels and CD34-positive immunostain. Histopathological study of primary non-trophoblastic tumors should differentiate chorangiosis from other entities, as the chorangiomatosis and choriocarcinoma, and this study should report the presence or absence of mesenchymal dysplasia because it is associated with genetic diseases. This neoplasm is associated with processes of fetal-placental hypoxia that must be assessed in patients with a history of fetal growth restriction, preeclampsia and multiple gestations.
authors.affiliation: Departamento de Patología, Facultad de Salud, Universidad Industrial de Santander, Bucaramanga, Colombia.
authors.forename: Gabriel E
authors.initials: GE
authors.lastname: Pérez García
authors.forename: Jairo A
authors.initials: JA
authors.lastname: Sierra Avendaño
authors.forename: Eulalia
authors.initials: E
authors.lastname: Rangel Navia
authors.forename: Juan S
authors.initials: JS
authors.lastname: Fuentes Porras
mesh_terms: D000328:Adult; D003105:Colombia; D005260:Female; D006391:Hemangioma / Q000473:pathology*; D006801:Humans; D010922:Placenta Diseases / Q000473:pathology*; D011247:Pregnancy