title: The ENCODE project: missteps overshadowing a success.
abstract: Two clichés of science journalism have now played out around the ENCODE project. ENCODE's publicity first presented a misleading "all the textbooks are wrong" narrative about noncoding human DNA. Now several critiques of ENCODE's narrative have been published, and one was so vitriolic that it fueled "undignified academic squabble" stories that focused on tone more than substance. Neither story line does justice to our actual understanding of genomes, to ENCODE's results, or to the role of big science in biology.
authors.affiliation: HHMI Janelia Farm Research Campus, Ashburn, VA 20147, USA. eddys@janelia.hhmi.org
authors.forename: Sean R
authors.initials: SR
authors.lastname: Eddy
mesh_terms: D019295:Computational Biology / Q000379:methods / Q000639:trends*; D021901:DNA, Intergenic / Q000235:genetics*; D030541:Databases, Genetic; D015894:Genome, Human / Q000235:genetics*; D006801:Humans; D012045:Regulatory Sequences, Nucleic Acid / Q000235:genetics*
chemical_list: D021901:DNA, Intergenic