title: Characteristic phenotypes in Korean Crohn's disease patients who underwent intestinal surgery for the treatment.
abstract: There are no previous large scale studies which have evaluated the phenotypes and clinical characteristics of Korean Crohn's disease patients who underwent intestinal resection. The purpose of this multicenter retrospective cohort study was to evaluate the clinical characteristics of Korean Crohn's disease patients who underwent intestinal resection during the study period. A total of 686 patients were enrolled in this study. The study period was over a 20-yr period (1990-2009). The patients were divided into the first-10-yr group and the second-10-yr group. The phenotypes and clinical characteristics were compared between the groups. The most common site of the disease was the ileal area (37.8%) and stricturing behavior was observed in 38.3% patients. The most common type of surgery was segmental resection of the small bowel (30.6%). These phenotypes showed a similar pattern in both the first and second study period groups and did not show any significant differences between the groups. The number of registered patients increased continuously. The phenotypes of Korean Crohn's disease patients who underwent intestinal resection are different compared with previously reported clinical characteristics of general Crohn's disease patients.
authors.affiliation: Section of Colon and Rectal Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Seung Hyuk
authors.initials: SH
authors.lastname: Baik
authors.forename: Kyu Joo
authors.initials: KJ
authors.lastname: Park
authors.forename: Kang Young
authors.initials: KY
authors.lastname: Lee
authors.forename: Yong Beom
authors.initials: YB
authors.lastname: Cho
authors.forename: Gyu-Seog
authors.initials: GS
authors.lastname: Choi
authors.forename: Kil Yeon
authors.initials: KY
authors.lastname: Lee
authors.forename: Sang Nam
authors.initials: SN
authors.lastname: Yoon
authors.forename: Chang Sik
authors.initials: CS
authors.lastname: Yu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D044466:Asian People; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003106:Colon / Q000601:surgery; D003424:Crohn Disease / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007082:Ileum / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D056910:Republic of Korea; D012189:Retrospective Studies; D055815:Young Adult
keywords: Crohn's Disease; Intestinal Surgery; Phenotypes