title: Molecular Optical Simulation Environment (MOSE): a platform for the simulation of light propagation in turbid media.
abstract: The study of light propagation in turbid media has attracted extensive attention in the field of biomedical optical molecular imaging. In this paper, we present a software platform for the simulation of light propagation in turbid media named the "Molecular Optical Simulation Environment (MOSE)". Based on the gold standard of the Monte Carlo method, MOSE simulates light propagation both in tissues with complicated structures and through free-space. In particular, MOSE synthesizes realistic data for bioluminescence tomography (BLT), fluorescence molecular tomography (FMT), and diffuse optical tomography (DOT). The user-friendly interface and powerful visualization tools facilitate data analysis and system evaluation. As a major measure for resource sharing and reproducible research, MOSE aims to provide freeware for research and educational institutions, which can be downloaded at http://www.mosetm.net.
authors.affiliation: School of Life Sciences and Technology, Xidian University, Xi'an, Shaanxi, China.
authors.forename: Shenghan
authors.initials: S
authors.lastname: Ren
authors.forename: Xueli
authors.initials: X
authors.lastname: Chen
authors.forename: Hailong
authors.initials: H
authors.lastname: Wang
authors.forename: Xiaochao
authors.initials: X
authors.lastname: Qu
authors.forename: Ge
authors.initials: G
authors.lastname: Wang
authors.forename: Jimin
authors.initials: J
authors.lastname: Liang
authors.forename: Jie
authors.initials: J
authors.lastname: Tian
mesh_terms: D000818:Animals; D055615:Electrical Equipment and Supplies; D008027:Light; D051379:Mice; D009010:Monte Carlo Method; D055620:Optical Phenomena; D019047:Phantoms, Imaging; D013997:Time Factors; D041622:Tomography, Optical