title: Brugada syndrome after using cold medicine: is there any relation?
abstract: Brugada syndrome (BrS) is associated with increased risk of ventricular arrhythmias and sudden death. Some drugs can trigger the electrocardiographic and arrhythmic manifestations of this syndrome. Cold medicines for symptom relief are sold without prescription in Brazil and most contain antihistamines and adrenergic agonists. We report a case of BrS probably triggered by the use of such medication.
authors.affiliation: Serviço de Eletrofisiologia, Instituto de Cardiologia, Fundação Universitária de Cardiologia do Rio Grande Do Sul, Porto Alegre, Brasil. drleiria@gmail.com
authors.forename: Tiago Luiz Luz
authors.initials: TL
authors.lastname: Leiria
authors.forename: Augusto
authors.initials: A
authors.lastname: Mantovani
authors.forename: Rafael
authors.initials: R
authors.lastname: de March Ronsoni
authors.forename: Leonardo
authors.initials: L
authors.lastname: Martins Pires
authors.forename: Marcelo
authors.initials: M
authors.lastname: Lapa Kruse
authors.forename: Gustavo
authors.initials: G
authors.lastname: Glotz de Lima
mesh_terms: D000328:Adult; D001977:Brompheniramine / Q000009:adverse effects*; D053840:Brugada Syndrome / Q000139:chemically induced*; D006634:Histamine H1 Antagonists / Q000009:adverse effects*; D006801:Humans; D008297:Male; D057985:Multi-Ingredient Cold, Flu, and Allergy Medications / Q000009:adverse effects; D014663:Nasal Decongestants / Q000009:adverse effects*; D010656:Phenylephrine / Q000009:adverse effects*
chemical_list: D006634:Histamine H1 Antagonists; D057985:Multi-Ingredient Cold, Flu, and Allergy Medications; D014663:Nasal Decongestants; D010656:Phenylephrine; D001977:Brompheniramine