title: Cystoid macular edema in a patient with Danon disease.
abstract: To report a patient with Danon retinopathy with cystoid macular edema treated with topical dorzolamide 2% eye drops and oral acetazolamide. A 37-year-old Caucasian man with Danon disease treated with topical and oral carbonic anhydrase inhibitors participated in the study. Examinations performed before and during treatment included visual acuity (VA), spectral-domain optical coherence tomography, and electroretinography. Following total 48 weeks of treatment, VA decreased from 20/30 OD, 20/200 OS, to 20/40 OD, CF OS. The mean central retinal thickness was unchanged from baseline 263 μm OD , 226 μm OS, after treatment 283 μm OD and 202 μm OS. In our case, carbonic anydrase inhibitors were not effective. However, a general recommendation cannot be given based on a single case.
authors.affiliation: Eye Surgery Associates, Melbourne, Australia.
authors.forename: Heather G
authors.initials: HG
authors.lastname: Mack
mesh_terms: D004596:Electroretinography; D052120:Glycogen Storage Disease Type IIb / Q000150:complications*; D006801:Humans; D008269:Macular Edema / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D041623:Tomography, Optical Coherence; D014792:Visual Acuity