title: A strategy for highly selective detection and imaging of hypochlorite using selenoxide elimination.
abstract: A new strategy for HOCl-specific fluorescent probes has been reported based on a selenoxide elimination reaction. Probes CM1 and CM2 were synthesized as the first fluorescent probes containing an arylseleno moiety for hypochlorite according to this strategy. Both probes displayed excellent properties, including high selectivity and sensitivity, fast response, and pH independency toward hypochlorite in vitro and vivo.
authors.affiliation: Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190 PR China.
authors.forename: Guoping
authors.initials: G
authors.lastname: Li
authors.forename: Dongjian
authors.initials: D
authors.lastname: Zhu
authors.forename: Qing
authors.initials: Q
authors.lastname: Liu
authors.forename: Lin
authors.initials: L
authors.lastname: Xue
authors.forename: Hua
authors.initials: H
authors.lastname: Jiang
mesh_terms: D003952:Diagnostic Imaging; D005456:Fluorescent Dyes / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D006997:Hypochlorous Acid / Q000032:analysis / Q000737:chemistry*; D015394:Molecular Structure; D016566:Organoselenium Compounds / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D016566:Organoselenium Compounds; D006997:Hypochlorous Acid