title: Increasing age associated with elevated cardio-ankle vascular index scores in patients with type 2 diabetes mellitus.
abstract: OBJECTIVE
  The study investigated the relationship between arterial stiffness calculated using the cardio-ankle vascular index (CAVI), diagnosis of type 2 diabetes mellitus and type 2 diabetes-related cardiovascular complications, in patients with type 2 diabetes mellitus (type 2 diabetes) and nondiabetic patients.
  
  
  METHODS
  A retrospective cross-sectional study was conducted in patients with type 2 diabetes and age-matched nondiabetic patients. CAVI was measured using an automatic vascular screening system. Parameters associated with type 2 diabetes and cardiovascular complications were also measured.
  
  
  RESULTS
  A total of 51 patients with type 2 diabetes and 59 nondiabetic patients were enrolled in the study. Significantly higher CAVI scores were observed in patients with type 2 diabetes compared with nondiabetic patients (mean ± SD: 9.55 ± 1.13 versus 8.54 ± 0.94, respectively). Multivariate linear regression analyses demonstrated that age was the only significant factor influencing the CAVI score, in patients with type 2 diabetes.
  
  
  CONCLUSIONS
  Patients with type 2 diabetes had an increased risk of arterial stiffness, based on the CAVI score, compared with nondiabetic patients; this, in turn, could increase their risk of developing other cardiovascular complications.
authors.affiliation: Department of Cardiology, General Hospital of Beijing Military Command, Beijing, China.
authors.forename: Guoxiang
authors.initials: G
authors.lastname: Tian
authors.forename: Wanlin
authors.initials: W
authors.lastname: Wei
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Ling
authors.initials: L
authors.lastname: Zhang
authors.forename: Hongshuai
authors.initials: H
authors.lastname: You
authors.forename: Wen
authors.initials: W
authors.lastname: Liu
authors.forename: Zhu
authors.initials: Z
authors.lastname: Sun
authors.forename: Xiaobing
authors.initials: X
authors.lastname: Wang
authors.forename: Xiao
authors.initials: X
authors.lastname: Wu
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology*; D000842:Ankle / Q000098:blood supply* / Q000503:physiopathology*; D002318:Cardiovascular Diseases / Q000150:complications* / Q000503:physiopathology*; D003710:Demography; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged
keywords: Type 2 diabetes mellitus; arterial stiffness; cardio–ankle vascular index; hypertension