title: European H16N3 gull influenza virus attaches to the human respiratory tract and eye.
abstract: We explored the attachment of an H16N3 influenza virus to human, mallard, and gull tissues using virus histochemistry applied to tissue microarrays and employing human and mallard viruses as references. Of the viruses tested, the H16N3 gull virus most readily attached to the human respiratory tract and eye. These results underscore the need to assess the potential for gull influenza viruses to replicate in human tissues and further investigate the role of gulls in influenza virus ecology.
authors.affiliation: Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Lindskog
authors.forename: Patrik
authors.initials: P
authors.lastname: Ellström
authors.forename: Björn
authors.initials: B
authors.lastname: Olsen
authors.forename: Fredrik
authors.initials: F
authors.lastname: Pontén
authors.forename: Debby
authors.initials: D
authors.lastname: van Riel
authors.forename: Vincent J
authors.initials: VJ
authors.lastname: Munster
authors.forename: Daniel
authors.initials: D
authors.lastname: González-Acuña
authors.forename: Thijs
authors.initials: T
authors.lastname: Kuiken
authors.forename: Elsa
authors.initials: E
authors.lastname: Jourdain
mesh_terms: D000818:Animals; D046091:Charadriiformes / Q000821:virology*; D004285:Dogs; D005060:Europe; D005123:Eye / Q000821:virology*; D006801:Humans; D009980:Influenza A virus / Q000502:physiology*; D061985:Madin Darby Canine Kidney Cells; D012137:Respiratory System / Q000821:virology*; D053585:Virus Attachment