title: Convergent approach to complex spirocyclic pyrans: practical synthesis of the oxa-pinnaic acid core.
abstract: The enantioselective synthesis of the oxa-pinnaic acid framework has been achieved through internal asymmetric induction. The synthetic strategy pursued illustrates the adaptability of the Achmatowicz oxidative rearrangement for the synthesis of complex spirocyclic pyrans starting from tertiary alcohols.
authors.affiliation: School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK.
authors.forename: Frank D
authors.initials: FD
authors.lastname: Ferrari
authors.forename: Adele E
authors.initials: AE
authors.lastname: Pasqua
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Ledgard
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Marquez
mesh_terms: D000470:Alkaloids / Q000737:chemistry*; D015394:Molecular Structure; D011714:Pyrans / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D000470:Alkaloids; D011714:Pyrans; D013141:Spiro Compounds; C412665:pinnaic acid