title: Enzymatic reactions on immobilised substrates.
abstract: This review gives an overview of enzymatic reactions that have been conducted on substrates attached to solid surfaces. Such biochemical reactions have become more important with the drive to miniaturisation and automation in chemistry, biology and medicine. Technical aspects such as choice of solid surface and analytical methods are discussed and examples of enzyme reactions that have been successful on these surfaces are provided.
authors.affiliation: School of Chemistry & Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Road, Manchester, M1 7DN, UK.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Gray
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Weissenborn
authors.forename: Claire E
authors.initials: CE
authors.lastname: Eyers
authors.forename: Sabine L
authors.initials: SL
authors.lastname: Flitsch
mesh_terms: D004798:Enzymes / Q000737:chemistry / Q000378:metabolism*; D013379:Substrate Specificity; D013499:Surface Properties
chemical_list: D004798:Enzymes