title: Genetics: a gene of rare effect.
authors.forename: Stephen S
authors.initials: SS
authors.lastname: Hall
mesh_terms: D000328:Adult; D001741:Black or African American / Q000235:genetics; D000818:Animals; D002784:Cholesterol / Q000097:blood / Q000235:genetics* / Q000378:metabolism*; D008076:Cholesterol, HDL / Q000097:blood / Q000235:genetics / Q000378:metabolism; D002986:Clinical Trials as Topic; D005260:Female; D056726:Genetic Association Studies; D005826:Genetics, Medical; D006331:Heart Diseases / Q000188:drug therapy / Q000201:enzymology / Q000235:genetics; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006937:Hypercholesterolemia / Q000201:enzymology / Q000235:genetics; D008297:Male; D051379:Mice; D009154:Mutation / Q000235:genetics; D000071449:Proprotein Convertase 9; D043484:Proprotein Convertases / Q000172:deficiency / Q000235:genetics* / Q000378:metabolism; D011973:Receptors, LDL / Q000378:metabolism; D012697:Serine Endopeptidases / Q000172:deficiency / Q000235:genetics* / Q000378:metabolism; D057170:Translational Research, Biomedical
chemical_list: D008076:Cholesterol, HDL; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D011973:Receptors, LDL; D002784:Cholesterol; C472125:PCSK9 protein, human; D000071449:Proprotein Convertase 9; D043484:Proprotein Convertases; D012697:Serine Endopeptidases