title: Dietary sources of lutein and zeaxanthin carotenoids and their role in eye health.
abstract: The eye is a major sensory organ that requires special care for a healthy and productive lifestyle. Numerous studies have identified lutein and zeaxanthin to be essential components for eye health. Lutein and zeaxanthin are carotenoid pigments that impart yellow or orange color to various common foods such as cantaloupe, pasta, corn, carrots, orange/yellow peppers, fish, salmon and eggs. Their role in human health, in particular the health of the eye, is well established from epidemiological, clinical and interventional studies. They constitute the main pigments found in the yellow spot of the human retina which protect the macula from damage by blue light, improve visual acuity and scavenge harmful reactive oxygen species. They have also been linked with reduced risk of age-related macular degeneration (AMD) and cataracts. Research over the past decade has focused on the development of carotenoid-rich foods to boost their intake especially in the elderly population. The aim of this article is to review recent scientific evidences supporting the benefits of lutein and zexanthin in preventing the onset of two major age-related eye diseases with diets rich in these carotenoids. The review also lists major dietary sources of lutein and zeaxanthin and refers to newly developed foods, daily intake, bioavailability and physiological effects in relation to eye health. Examples of the newly developed high-lutein functional foods are also underlined.
authors.affiliation: Guelph Food Research Centre, Agriculture and Agri-Food Canada, Guelph, ON N1G 5C9, Canada. elsayed.abdelaal@agr.gc.ca.
authors.forename: El-Sayed M
authors.initials: el-SM
authors.lastname: Abdel-Aal
authors.forename: Humayoun
authors.initials: H
authors.lastname: Akhtar
authors.forename: Khalid
authors.initials: K
authors.lastname: Zaheer
authors.forename: Rashida
authors.initials: R
authors.lastname: Ali
mesh_terms: D002386:Cataract / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control*; D004032:Diet; D005123:Eye / Q000378:metabolism* / Q000503:physiopathology; D055951:Functional Food; D006801:Humans; D014975:Lutein / Q000008:administration & dosage* / Q000378:metabolism; D008268:Macular Degeneration / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control*; D009752:Nutritional Status; D009753:Nutritive Value; D024341:Xanthophylls / Q000008:administration & dosage* / Q000378:metabolism; D065146:Zeaxanthins
chemical_list: D024341:Xanthophylls; D065146:Zeaxanthins; D014975:Lutein