title: Differentials and approach to leukocoria.
abstract: Leukocoria is an important clinical examination finding as it can be a sign of significant intraocular pathology, with the most common being retinoblastoma and congenital cataracts. The Brückner test is a quick, easy, and inexpensive way to assess the red reflex. When leukocoria is suspected, prompt referral to an ophthalmologist is necessary for further evaluation.
authors.affiliation: Yale New Haven Hospital, USA. nishdpatel@gmail.com
authors.forename: Nishita
authors.initials: N
authors.lastname: Patel
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Salchow
authors.forename: Miguel
authors.initials: M
authors.lastname: Materin
mesh_terms: D002386:Cataract / Q000150:complications / Q000151:congenital / Q000175:diagnosis*; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D054514:Persistent Hyperplastic Primary Vitreous / Q000150:complications; D011681:Pupil Disorders / Q000175:diagnosis* / Q000209:etiology; D019572:Retinal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D012175:Retinoblastoma / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D012178:Retinopathy of Prematurity / Q000150:complications; D014120:Toxocariasis / Q000150:complications