title: A microthymoma and no germinal centre in myasthenia gravis.
abstract: A 43-year-old woman with a 1-year history of generalized myasthenia gravis was referred for a video-assisted thorascopic surgery thymectomy. The preoperative chest computed tomography revealed mild diffuse thymic hyperplasia. Pathology of the resected thymus gland revealed a 6-mm World Health Organization (WHO) Type AB microthymoma without thymic germinal centres. The entity of microthymoma was reviewed with a focus on examining the pathological and therapeutic differences between thymic hyperplasia and microscopic thymoma.
authors.affiliation: Division of Thoracic Surgery, The Brigham and Women's Hospital, Boston, MA, USA.
authors.forename: Masatsugu
authors.initials: M
authors.lastname: Hamaji
authors.forename: Paul A
authors.initials: PA
authors.lastname: Vanderlaan
authors.forename: David J
authors.initials: DJ
authors.lastname: Sugarbaker
authors.forename: Ciaran J
authors.initials: CJ
authors.lastname: McNamee
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D009157:Myasthenia Gravis / Q000473:pathology* / Q000601:surgery; D013902:Radiography, Thoracic; D013934:Thymectomy; D013945:Thymoma / Q000473:pathology* / Q000601:surgery; D020535:Video-Assisted Surgery
keywords: Myasthenia gravis; Surgery; Thymoma