title: Non small-cell lung cancer with metastasis to thigh muscle and mandible: two case reports.
abstract: BACKGROUND
  Lung cancer is the leading cause of cancer-related death in Europe and the US. Isolated metastases to skeletal muscle and the mandible are very uncommon.
  
  
  METHODS
  This report presents two cases. Case 1 concerns a 45-year-old Caucasian woman affected by muscle metastasis of the right thigh from non-small-cell lung cancer. Case 2 concerns a 61-year-old Caucasian man affected by mandible metastasis from non-small-cell lung cancer. Both metastases were detected by diagnostic imaging studies. Both patients were treated with radiation therapy with palliative and antalgic intent.
  
  
  CONCLUSIONS
  Radiation therapy was effective and well tolerated in both cases. Both our patients are alive, with follow-up of 18 months and five months, respectively.
authors.affiliation: Radiation Therapy Department, National Cancer Institute, Pascale Foundation, Naples, Italy. francesca_giugliano@hotmail.com.
authors.forename: Francesca Maria
authors.initials: FM
authors.lastname: Giugliano
authors.forename: Domingo
authors.initials: D
authors.lastname: Alberti
authors.forename: Giovanna
authors.initials: G
authors.lastname: Guida
authors.forename: Giampaolo De
authors.initials: GD
authors.lastname: Palma
authors.forename: Luciano
authors.initials: L
authors.lastname: Iadanza
authors.forename: Maria
authors.initials: M
authors.lastname: Mormile
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Cammarota
authors.forename: Agnese
authors.initials: A
authors.lastname: Montanino
authors.forename: Franco
authors.initials: F
authors.lastname: Fulciniti
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Ravo
authors.forename: Paolo
authors.initials: P
authors.lastname: Muto