title: Primary Sjögren's syndrome prevalence in a major metropolitan area in Brazil.
abstract: There has been no previous prevalence study about of Sjögren's syndrome (SS) in Brazil. The aim was to evaluate the SS prevalence in a general population in Vitória, ES, Brazil. This was an epidemiological, observational, and cross-sectional study conducted on 1,205 randomized people, aged 18-65 years, who lived in Vitória. The subjects were screened for xerostomia and xerofphthalmia through home interviews. Those with sicca symptoms were asked to report to a hospital for further medical evaluation, unstimulated salivary flow, Schirmer I test, blood analysis and minor labial salivary biopsy. Sicca symptoms were found in 18% (217 subjects) of the sample. Of the 217 subjects with sicca symptoms, 127 (58%) were available for examination. In this sample, 61.7% were female and 46.8% were under medication. Sicca syndrome was confirmed in 12% by at least one examination (salivary flow or Schirmer I). Two patients (0.17%) matched four criteria according to American-European Criteria (95% CI = 0.020-0.5983).
authors.affiliation: Universidade Federal de São Paulo, Brazil. val.valim@gmail.com
authors.forename: Valéria
authors.initials: V
authors.lastname: Valim
authors.forename: Eliana
authors.initials: E
authors.lastname: Zandonade
authors.forename: Ana Maria
authors.initials: AM
authors.lastname: Pereira
authors.forename: Odvaldo Honor
authors.initials: OH
authors.lastname: de Brito Filho
authors.forename: Erica Vieira
authors.initials: EV
authors.lastname: Serrano
authors.forename: Carlos
authors.initials: C
authors.lastname: Musso
authors.forename: Raquel Altoé
authors.initials: RA
authors.lastname: Giovelli
authors.forename: Rozana Mesquita
authors.initials: RM
authors.lastname: Ciconelli
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000453:epidemiology*; D014504:Urban Health; D055815:Young Adult