title: Illustrative cases of unorthodox tinnitus management.
abstract: Bone remodeling disorders have been identified as potential candidates for the etiology underlying some forms of otologic disease. Here, four clinical cases are presented to demonstrate a novel approach to tinnitus management that focuses on two fundamental etiologic bases. First, is the effect of bone remodeling abnormalities of the otic capsule and second, the effect of blood sugar and insulin abnormalities upon the function of the inner ear and self-reports of tinnitus. This report presents the effect of treatment directed at bone remodeling abnormalities of the otic capsule and abnormalities of blood sugar and insulin. The treatment effects led to a substantial reduction in subjective tinnitus. These findings suggest a potential convergence between bone pathophysiology and some forms of tinnitus.
authors.affiliation: Aerospace Medicine and Vestibular Research Laboratory, Mayo Clinic, Phoenix, AZ, USA. khbrooklermd@mac.com
authors.forename: Kenneth H
authors.initials: KH
authors.lastname: Brookler
mesh_terms: D000328:Adult; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D004035:Diet Therapy; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000150:complications* / Q000178:diet therapy; D007759:Labyrinth Diseases / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications* / Q000188:drug therapy; D012969:Sodium Fluoride / Q000627:therapeutic use; D014012:Tinnitus / Q000209:etiology / Q000628:therapy*
chemical_list: D050071:Bone Density Conservation Agents; D012969:Sodium Fluoride