title: Multiple skin chloromas: a rare presentation of chronic myelogenous leukaemia in chronic stable phase.
abstract: Chloroma, also called granulocytic sarcoma or myeloid sarcoma, is a rare malignant extramedullary neoplasm of myeloid precursor cells that occurs usually in association with acute myeloid leukaemia or blast phase of chronic myeloid leukaemia (CML). The chloromas are regarded as an early herald of a systemic relapse, rather than as a localised process. The author reports a rare case of multiple skin chloromas in the chronic phase of CML. The patient was treated initially with hydroxyurea and chloromas disappeared. Patient has been followed for around three and half years and maintained in chronic stable phase on imatinib therapy.
authors.affiliation: Department of Internal Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India. drvivek2@rediffmail.com
authors.forename: Vivek
authors.initials: V
authors.lastname: Kumar
authors.forename: Nirdesh
authors.initials: N
authors.lastname: Jain
authors.forename: Shyam Chand
authors.initials: SC
authors.lastname: Chaudhary
authors.forename: Sanjay
authors.initials: S
authors.lastname: Mishra
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001549:Benzamides / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use; D000068877:Imatinib Mesylate; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D010879:Piperazines / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use; D023981:Sarcoma, Myeloid / Q000188:drug therapy / Q000209:etiology*; D012878:Skin Neoplasms / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000970:Antineoplastic Agents; D001549:Benzamides; D010879:Piperazines; D011743:Pyrimidines; D000068877:Imatinib Mesylate; D006918:Hydroxyurea