title: Control of iron metabolism in bacteria.
abstract: Bacteria depend upon iron as a vital cofactor that enables a wide range of key metabolic activities. Bacteria must therefore ensure a balanced supply of this essential metal. To do so, they invest considerable resourse into its acquisition and employ elaborate control mechanisms to eleviate both iron-induced toxitiy as well as iron deficiency. This chapter describes the processes that bacteria engage in maintaining iron homeostasis. The focus is Escherichia coli, as this bacterium provides a well studied example. A summary of the current status of understanding of iron management at the 'omics' level is also presented.
authors.affiliation: The School of Biological Sciences, The University of Reading, Whiteknights, Reading, RG6 6AJ, UK, s.c.andrews@reading.ac.uk.
authors.forename: Simon
authors.initials: S
authors.lastname: Andrews
authors.forename: Ian
authors.initials: I
authors.lastname: Norton
authors.forename: Arvindkumar S
authors.initials: AS
authors.lastname: Salunkhe
authors.forename: Helen
authors.initials: H
authors.lastname: Goodluck
authors.forename: Wafaa S M
authors.initials: WS
authors.lastname: Aly
authors.forename: Hanna
authors.initials: H
authors.lastname: Mourad-Agha
authors.forename: Pierre
authors.initials: P
authors.lastname: Cornelis
mesh_terms: D001419:Bacteria / Q000378:metabolism; D006706:Homeostasis; D007501:Iron / Q000378:metabolism
chemical_list: D007501:Iron