title: A simple fluorescent probe for Cd2+ in aqueous solution with high selectivity and sensitivity.
abstract: A simple quinoline-based fluorescent probe, PBQ, which contained a tweezer-like receptor, was successfully developed via one-step synthesis. PBQ exhibited a 40-fold fluorescence enhancement response to Cd(2+) in aqueous solution. PBQ was found to have excellent selectivity for Cd(2+) over many other metal ions (Ba(2+), Mn(2+), Hg(2+), Ni(2+), Ca(2+), Cu(2+), Co(2+), Pb(2+), Mg(2+), Zn(2+), Fe(2+), Fe(3+), Cr(3+), Ag(+), Li(+), Na(+), K(+)). Significantly, its fluorescence intensity was enhanced in a linear fashion with the concentration of Cd(2+). Thus PBQ can be potentially used for the quantification of Cd(2+). Moreover, a series of model compounds were rationally designed and synthesized in order to explore the binding mode of PBQ with Cd(2+).
authors.affiliation: Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai, 200237, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Xu
authors.forename: Meng-Lan
authors.initials: ML
authors.lastname: He
authors.forename: Hai-Bo
authors.initials: HB
authors.lastname: Yang
authors.forename: Xuhong
authors.initials: X
authors.lastname: Qian
mesh_terms: D001665:Binding Sites / Q000502:physiology; D040761:Biomimetic Materials / Q000737:chemistry* / Q000378:metabolism; D002104:Cadmium / Q000032:analysis* / Q000378:metabolism; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000378:metabolism; D012996:Solutions / Q000032:analysis; D014867:Water / Q000032:analysis*
chemical_list: D005456:Fluorescent Dyes; D012996:Solutions; D002104:Cadmium; D014867:Water