title: Pre-treatment with EDTA-gallium prevents the formation of biofilms on surfaces.
abstract: Pseudomonas aeruginosaandStreptococcus pyogenesare leading causes of medical device-associated infections. The capacity to establish and maintain these infections is thought to be associated with the ability to form surface-attached biofilms. In the present study, gallium nitrate was used to coat PVC plates and biofilm formation on the plates byPseudomonas aeruginosaandStreptococcus pyogeneswas evaluated. The results demonstrated that coating the PVC surface with gallium reduced bacteria cell aggregation on the PVC surface and inhibited biofilm formation. These results suggest that surface pre-treatment with a gallium nitrate coating is a potential strategy for the prevention of infections associated withPseudomonas aeruginosaorStreptococcus pyogeneson medical devices.
authors.affiliation: Nanjing Junxie Hospital, Nanjing, Jiangsu;
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Zhu
authors.forename: Feng
authors.initials: F
authors.lastname: Jin
authors.forename: Shuangwang
authors.initials: S
authors.lastname: Yang
authors.forename: Jingnong
authors.initials: J
authors.lastname: Li
authors.forename: Dan
authors.initials: D
authors.lastname: Hu
authors.forename: Lianming
authors.initials: L
authors.lastname: Liao
keywords: biofilm; gallium