title: Unilateral nasal pain with migraine features.
abstract: BACKGROUND
  Migraine attacks exclusively felt in the face are very rare, the pain involving the territories supplied by the second and third branches of the trigeminal nerve.
  
  
  METHODS
  Two patients suffering from heminasal pain attacks accompanied with typical migrainous features and responsive to oral or intranasal triptans - but not to intranasal lidocaine or oxymetazoline. In one patient, the attacks could be precipitated upon slight touching on the tip of the nose, in the other attacks were preceded by the nasal sensation typically heralding sneezing.
  
  
  CONCLUSIONS
  Migraine pain mostly develops within the innervation territory of the first branch of the trigeminal nerve, which includes the nose. Therefore, episodes of unilateral nasal pain with migrainous features could be considered a migraine with unusual topography (nasal migraine). Painful nasal attacks occasionally preceded by stimulation of trigeminal afferents in the nose, could be conceived of as migraine-tic syndrome.
authors.affiliation: Neurological Department, Fundación Alcorcón University Hospital, Spain. malvarezm@fhalcorcon.es
authors.forename: Mónica
authors.initials: M
authors.lastname: Alvarez
authors.forename: Teresa
authors.initials: T
authors.lastname: Montojo
authors.forename: Beatriz
authors.initials: B
authors.lastname: de la Casa
authors.forename: Lydia
authors.initials: L
authors.lastname: Vela
authors.forename: Juan A
authors.initials: JA
authors.lastname: Pareja
mesh_terms: D000281:Administration, Intranasal; D000368:Aged; D000700:Analgesics / Q000008:administration & dosage*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000150:complications* / Q000188:drug therapy; D009666:Nose; D010146:Pain / Q000188:drug therapy / Q000209:etiology*; D014363:Tryptamines / Q000008:administration & dosage*
chemical_list: D000700:Analgesics; D014363:Tryptamines
keywords: Facial migraine; idiopathic rhinalgia; lower-half headache; migraine-tic syndrome; nasal migraine