title: PPh3-mediated intramolecular conjugation of alkyl halides with electron-deficient olefins: facile synthesis of chromans and relevant analogues.
abstract: With the mediation of phosphine, the direct intramolecular coupling of two electrophiles - alkyl halides with electron-deficient olefins - has been successfully realized in an intramolecular conjugate addition manner. The reaction provides a new approach for the synthesis of chromans and relevant analogues.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China.
authors.forename: Jian-Bo
authors.initials: JB
authors.lastname: Zhu
authors.forename: Peng
authors.initials: P
authors.lastname: Wang
authors.forename: Saihu
authors.initials: S
authors.lastname: Liao
authors.forename: Yong
authors.initials: Y
authors.lastname: Tang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002839:Chromans / Q000138:chemical synthesis* / Q000737:chemistry; D004583:Electrons; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D015394:Molecular Structure; D010720:Phosphines / Q000737:chemistry*
chemical_list: D000475:Alkenes; D002839:Chromans; D006846:Hydrocarbons, Halogenated; D010720:Phosphines; C044646:phosphine