title: Pharmacognostic study and anti-inflammatory activity of Callistemon lanceolatus leaf.
abstract: OBJECTIVE
  To study detail pharmacognosy and anti-inflammatory activity of Callistemon lanceolatus (C. lanceolatus) leaf.
  
  
  METHODS
  Leaf sample was studied by organoleptic, macroscopical, microscopical, phytochemical and other WHO recommended methods for standardizations. The methanolic leaf extract of the plant was also screened for anti-inflammatory activity on carrageenan-induced paw edema in rat at doses of 200 and 400 mg/kg, orally. The detail pharmacognostic study of the C. lanceolatus leaf was carried out to lay down the standards which could be useful in future experimental studies.
  
  
  RESULTS
  C. lanceolatus methanolic leaf extract showed significant (P<0.05) anti-inflammatory activity at doses of 200 mg/kg and 400 mg/kg. This significant anti-inflammatory of C. lanceolatus methanolic leaf extract at the dose of 400 mg/kg was comparable with diclofenac sodium.
  
  
  CONCLUSIONS
  The pharmacognostic profile of the C. lanceolatus leaf is helpful in standardization for quality, purity and sample identification. The methanolic extract at a dose of 400 mg/kg shows a significant activity in comparison with the standard drug diclofenac sodium (50 mg/kg).
authors.affiliation: Institute of Pharmaceutical Sciences, Kurukshetra University, Haryana, India.
authors.forename: S
authors.initials: S
authors.lastname: Kumar
authors.forename: V
authors.initials: V
authors.lastname: Kumar
authors.forename: O M
authors.initials: OM
authors.lastname: Prakash
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D005260:Female; D008297:Male; D010641:Phenotype; D064209:Phytochemicals / Q000737:chemistry / Q000494:pharmacology; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves / Q000737:chemistry* / Q000166:cytology; D051381:Rats; D013997:Time Factors; D064028:Tracheophyta / Q000737:chemistry*
chemical_list: D000893:Anti-Inflammatory Agents; D064209:Phytochemicals; D010936:Plant Extracts
keywords: Anti-inflammatory; Callistemon lanceolatus; Carragennan; Fibre; Microscopy; Stomata