title: Silicon photonic micro-disk resonators for label-free biosensing.
abstract: Silicon photonic biosensors are highly attractive for multiplexed Lab-on-Chip systems. Here, we characterize the sensing performance of 3 µm TE-mode and 10 µm dual TE/TM-mode silicon photonic micro-disk resonators and demonstrate their ability to detect the specific capture of biomolecules. Our experimental results show sensitivities of 26 nm/RIU and 142 nm/RIU, and quality factors of 3.3x10(4) and 1.6x10(4) for the TE and TM modes, respectively. Additionally, we show that the large disks contain both TE and TM modes with differing sensing characteristics. Finally, by serializing multiple disks on a single waveguide bus in a CMOS compatible process, we demonstrate a biosensor capable of multiplexed interrogation of biological samples.
authors.affiliation: Department of Electrical and Computer Engineering, The University of British Columbia, 2332 Main Mall, Vancouver, BC. V6T 1Z4, Canada. sgrist@ece.ubc.ca
authors.forename: Samantha M
authors.initials: SM
authors.lastname: Grist
authors.forename: Shon A
authors.initials: SA
authors.lastname: Schmidt
authors.forename: Jonas
authors.initials: J
authors.lastname: Flueckiger
authors.forename: Valentina
authors.initials: V
authors.lastname: Donzella
authors.forename: Wei
authors.initials: W
authors.lastname: Shi
authors.forename: Sahba
authors.initials: S
authors.lastname: Talebi Fard
authors.forename: James T
authors.initials: JT
authors.lastname: Kirk
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Ratner
authors.forename: Karen C
authors.initials: KC
authors.lastname: Cheung
authors.forename: Lukas
authors.initials: L
authors.lastname: Chrostowski
mesh_terms: D001704:Biopolymers / Q000032:analysis*; D015374:Biosensing Techniques / Q000295:instrumentation*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D008904:Miniaturization; D012031:Refractometry / Q000295:instrumentation*; D012825:Silicon / Q000737:chemistry*; D013194:Staining and Labeling; D020349:Surface Plasmon Resonance / Q000295:instrumentation*
chemical_list: D001704:Biopolymers; D012825:Silicon