title: [Pemphigus vulgaris. Therapy with cyclophosphamide].
abstract: Pemphigus vulgaris is an autoimmune blistering disorder. The diagnosis is based on clinical presentation, histology, and direct and indirect immunofluorescence. Optimal treatment remains the greatest challenge. Treatment options include combinations of systemic steroids with azathioprine, mycophenolate, and cyclophosphamide. However, there is little solid data regarding the drug of choice. In our patient, the best tolerated and effective treatment was found after several therapeutic attempts.
authors.affiliation: Klinik für Allergologie und Dermatologie, Universitätsklinikum RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, Germany. lvanstreels@ukaachen.de
authors.forename: L
authors.initials: L
authors.lastname: Vanstreels
authors.forename: A
authors.initials: A
authors.lastname: Alkhateeb
authors.forename: M
authors.initials: M
authors.lastname: Megahed
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage*; D003907:Dexamethasone / Q000008:administration & dosage*; D004359:Drug Therapy, Combination / Q000379:methods; D005148:Facial Dermatoses / Q000188:drug therapy* / Q000473:pathology*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008875:Middle Aged; D010392:Pemphigus / Q000188:drug therapy* / Q000473:pathology*; D017211:Treatment Failure
chemical_list: D000893:Anti-Inflammatory Agents; D007166:Immunosuppressive Agents; D003907:Dexamethasone; D003520:Cyclophosphamide