title: Optic nerve: separating compartments based on 23Na TQF spectra and TQF-diffusion anisotropy.
abstract: We present a triple quantum filtered (TQF) sodium spectroscopy study of an excised bovine optic nerve. By choosing proper experimental parameters, this technique allowed us to independently observe the satellite transitions originating from the various compartments in the tissue. TQF-based diffusion experiments provided further characterization of the compartments in terms of their geometry. As a result, the peak that exhibited the smallest residual quadrupolar splitting, and the largest diffusion anisotropy was assigned to axons. Two other pairs of satellite peaks were assigned to extra-cellular compartments on the basis of either the size of their quadrupolar splitting or the diffusion properties.
authors.affiliation: School of Chemistry, Tel Aviv University, Ramat Aviv, Tel Aviv, 69978, Israel.
authors.forename: Uzi
authors.initials: U
authors.lastname: Eliav
authors.forename: Xiang
authors.initials: X
authors.lastname: Xu
authors.forename: Alexej
authors.initials: A
authors.lastname: Jerschow
authors.forename: Gil
authors.initials: G
authors.lastname: Navon
mesh_terms: D000465:Algorithms; D000818:Animals; D000829:Animals, Domestic; D002417:Cattle; D004058:Diffusion; D066298:In Vitro Techniques; D009900:Optic Nerve / Q000737:chemistry*; D012975:Sodium Isotopes / Q000032:analysis* / Q000737:chemistry*
chemical_list: D012975:Sodium Isotopes