title: Evaluation of the βLACTA test, a novel commercial chromogenic test for rapid detection of ceftazidime-nonsusceptible Pseudomonas aeruginosa isolates.
abstract: A novel commercial chromogenic technique, the βLACTA test (Bio-Rad, Marnes-la-Coquette, France), was evaluated to detect nonsusceptibility to ceftazidime in Pseudomonas aeruginosa isolates. Easily implemented in the routine microbiology laboratory, this rapid test was sensitive (95%) and specific (87%) and presented negative and positive predictive values of 99% and 100%, respectively.
authors.affiliation: National Reference Laboratory for Monitoring of Antimicrobial Resistance in Gram-Negative Bacteria, CHU Mont-Godinne-Dinant, Université Catholique de Louvain, Yvoir, Belgium.
authors.forename: Terry
authors.initials: T
authors.lastname: Laurent
authors.forename: Te-Din
authors.initials: TD
authors.lastname: Huang
authors.forename: Pierre
authors.initials: P
authors.lastname: Bogaerts
authors.forename: Youri
authors.initials: Y
authors.lastname: Glupczynski
mesh_terms: D000900:Anti-Bacterial Agents / Q000378:metabolism / Q000494:pharmacology*; D001431:Bacteriological Techniques / Q000379:methods*; D002442:Ceftazidime / Q000378:metabolism / Q000494:pharmacology*; D002863:Chromogenic Compounds / Q000378:metabolism*; D003124:Colorimetry / Q000379:methods; D005602:France; D006801:Humans; D011552:Pseudomonas Infections / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000201:enzymology / Q000302:isolation & purification; D012680:Sensitivity and Specificity; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000032:analysis*
chemical_list: D000900:Anti-Bacterial Agents; D002863:Chromogenic Compounds; D002442:Ceftazidime; D001618:beta-Lactamases