title: Gold-catalyzed synthesis of glyoxals by oxidation of terminal alkynes: one-pot synthesis of quinoxalines.
abstract: From terminal alkynes to glyoxals: Terminal alkynes can be oxidized under mild conditions by the use of an N-oxide in the presence of a gold catalyst. The intermediate glyoxal derivatives can be transferred in a one-pot procedure to substituted quinoxalines (see scheme).
authors.affiliation: Organisch-Chemisches Institut, Ruprecht-Karls-Universität Heidelberg, Im Neuenheimer Feld 270, 69120 Heidelberg, Germany.
authors.forename: Shuai
authors.initials: S
authors.lastname: Shi
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.forename: Weibo
authors.initials: W
authors.lastname: Yang
authors.forename: Matthias
authors.initials: M
authors.lastname: Rudolph
authors.forename: A Stephen K
authors.initials: AS
authors.lastname: Hashmi
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D020650:Combinatorial Chemistry Techniques; D006037:Glyoxal / Q000138:chemical synthesis* / Q000737:chemistry; D006046:Gold / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011810:Quinoxalines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000480:Alkynes; D011810:Quinoxalines; D006037:Glyoxal; D006046:Gold