title: Acinar cell cystadenoma of the pancreas in a cat.
abstract: Cystic tumours of the pancreas are heterogeneous lesions with a spectrum of morphology and biological behaviour in people. These are poorly characterized in animals. A multicystic tumour of the pancreas was identified in an 11-year-old, female, mixed breed cat. The tumour was 5.5 cm in diameter and the largest cysts were 1.5 cm in diameter. Microscopically, the cysts were lined by single layered or pseudostratified, flat, cuboidal or columnar epithelial cells that occasionally formed papillary structures with a thin fibrous core. The tumour cells had eosinophilic granules in the apical cytoplasm, similar to zymogen granules, and the nuclei were uniform in size and shape. Mitotic figures were not observed. Immunohistochemically, the tumour cells expressed trypsin, but not cytokeratin 7. A diagnosis of acinar cell cystadenoma of the pancreas was made and this is the first report of this tumour in a cat.
authors.affiliation: Department of Pathology and Integrative Oncological Pathology, Nippon Medical School, Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yoshimura
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuda
authors.forename: Y
authors.initials: Y
authors.lastname: Kawamoto
authors.forename: M
authors.initials: M
authors.lastname: Michishita
authors.forename: K
authors.initials: K
authors.lastname: Ohkusu-Tsukada
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: Z
authors.initials: Z
authors.lastname: Naito
authors.forename: T
authors.initials: T
authors.lastname: Ishiwata
mesh_terms: D061354:Acinar Cells / Q000473:pathology*; D000818:Animals; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D003537:Cystadenoma / Q000473:pathology / Q000662:veterinary*; D005260:Female; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000662:veterinary*
keywords: acinar cell cystadenoma; cat; pancreas