title: Amperometric glucose sensor based on nickel nanoparticles/carbon Vulcan XC-72R.
abstract: A stable non-enzymatic glucose sensor was constructed by chemical deposition of nickel nanoparticles on carbon Vulcan XC-72R using microwave irradiation technique. The mode and time of microwave irradiation during nickel salt reduction were varied. This was found to affect the morphology of formed Ni/C powder as evidenced by TEM analysis. Nickel nanoparticles aggregation becomes more serious at longer microwave irradiation times. The electrocatalytic activity of different Ni/C samples towards glucose oxidation was studied in KOH solution by employing cyclic voltammetry and chronoamperometry techniques. Ni/C sample, prepared by pulse mode with total operating time of 150s, showed the highest oxidation current density. An excellent sensitivity value of 1349.7μAmM(-1)cm(-2) with a detection limit of 0.232μM was gained by Ni/C sensor. It also exhibits good reproducibility and long-term stability, as well as high selectivity with insignificant interference from ascorbic acid.
authors.affiliation: Chemistry department, Faculty of Science, Cairo University, Giza, Egypt. randa311eg@yahoo.com
authors.forename: R M
authors.initials: RM
authors.lastname: Abdel Hameed
mesh_terms: D015374:Biosensing Techniques; D002244:Carbon / Q000737:chemistry; D055664:Electrochemical Techniques; D004566:Electrodes; D005947:Glucose / Q000737:chemistry / Q000302:isolation & purification*; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry*; D009532:Nickel / Q000737:chemistry*; D010084:Oxidation-Reduction
chemical_list: D002244:Carbon; D009532:Nickel; D005947:Glucose