title: Mucosal-incision assisted biopsy for suspected gastric gastrointestinal stromal tumors.
abstract: To evaluate the diagnostic yield of the procedure, mucosal-incision assisted biopsy (MIAB), for the histological diagnosis of gastric gastrointestinal stromal tumor (GIST), we performed a retrospective review of the 27 patients with suspected gastric GIST who underwent MIAB in our hospitals. Tissue samples obtained by MIAB were sufficient to make a histological diagnosis (diagnostic MIAB) in 23 out of the 27 patients, where the lesions had intraluminal growth patterns. Alternatively, the samples were insufficient (non-diagnostic MIAB) in remaining 4 patients, three of whom had gastric submucosal tumor with extraluminal growth patterns. Although endoscopic ultrasound and fine needle aspiration is the gold standard for obtaining tissue specimens for histological and cytological analysis of suspected gastric GISTs, MIAB can be used as an alternative method for obtaining biopsy specimens of lesions with an intraluminal growth pattern.
authors.affiliation: Eikichi Ihara, Kazuhiko Nakamura, Ryoichi Takayanagi, Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka 812-8582, Japan.
authors.forename: Eikichi
authors.initials: E
authors.lastname: Ihara
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsuzaka
authors.forename: Kuniomi
authors.initials: K
authors.lastname: Honda
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Hata
authors.forename: Yorinobu
authors.initials: Y
authors.lastname: Sumida
authors.forename: Hirotada
authors.initials: H
authors.lastname: Akiho
authors.forename: Tadashi
authors.initials: T
authors.lastname: Misawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Toyoshima
authors.forename: Yoshiharu
authors.initials: Y
authors.lastname: Chijiiwa
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Nakamura
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Takayanagi
keywords: Endoscopic submucosal dissection; Endoscopic ultrasound-guided fine-needle aspiration; Gastrointestinal stromal tumor; Mucosal-incision assisted biopsy; Submucosal tumor