title: Epidemiology of severe influenza outcomes among adult patients with obesity in Detroit, Michigan, 2011.
abstract: We conducted a retrospective cohort study to evaluate the impact of obesity on influenza disease severity. Individuals with obesity were more likely to have lower pulmonary disease manifestations [OR=1·97 (95% CI 1·05, 3·69), P=0·03] and to be admitted to an inpatient ward [OR=2·93 (95% CI 1·50, 5·71), P=0·002] when compared with non-obese individuals. Among admitted individuals, persons with obesity were more likely to require a lengthy hospital stay [OR=3·86 (95% CI 1·03, 14·42), P=0·045]. Five of the six deaths in study subjects occurred in persons with obesity.
authors.affiliation: Department of Pharmacy Practice, Wayne State University, Detroit, MI, USA.
authors.forename: Emily T
authors.initials: ET
authors.lastname: Martin
authors.forename: Carolyn
authors.initials: C
authors.lastname: Archer
authors.forename: John
authors.initials: J
authors.lastname: McRoberts
authors.forename: Janice
authors.initials: J
authors.lastname: Kulik
authors.forename: Taylor
authors.initials: T
authors.lastname: Thurston
authors.forename: Paul
authors.initials: P
authors.lastname: Lephart
authors.forename: Keith S
authors.initials: KS
authors.lastname: Kaye
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007251:Influenza, Human / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology*; D007902:Length of Stay; D008297:Male; D008824:Michigan / Q000453:epidemiology; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D011024:Pneumonia, Viral / Q000453:epidemiology / Q000401:mortality / Q000473:pathology; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome
keywords: Body mass index; influenza - human; obesity