title: Vascular contribution to Alzheimer disease: predictors of rapid progression.
abstract: Different courses of Alzheimer disease are observed in clinical practice. The rapidly progressive form could be associated with the presence of a major microcirculatory involvement and hemodynamic insufficiency. This short review aims to provide an overview of the current knowledge of cerebrovascular contribution to Alzheimer disease presentation and progression, hypothesizing the possible vascular markers of rapidly progressive form.
authors.affiliation: Department of Neuroscience, University of Rome Tor Vergata, Italy. Marina.Diomedi@uniroma2.it
authors.forename: Marina
authors.initials: M
authors.lastname: Diomedi
authors.forename: Giulia
authors.initials: G
authors.lastname: Misaggi
mesh_terms: D000544:Alzheimer Disease / Q000150:complications* / Q000175:diagnosis; D001812:Blood-Brain Barrier / Q000473:pathology / Q000503:physiopathology; D018450:Disease Progression; D004727:Endothelium / Q000098:blood supply / Q000473:pathology; D006801:Humans; D008833:Microcirculation; D011237:Predictive Value of Tests; D012039:Regional Blood Flow / Q000502:physiology; D014652:Vascular Diseases / Q000175:diagnosis / Q000209:etiology*