title: [Prognostic factors of resected metastatic lung tumor originated from renal cell carcinoma].
abstract: We performed retrospective analysis of 22 cases who received pulmonary resection of metastases originated from renal cell carcinoma between 1997 and 2011. Patients comprised 18 men and 4 women with a mean age of 63 years (range, 39~79). The total pulmonary resection was 30 times, lobectomy was performed 5 times and wedge resection was 25 times. The 5-year overall survival was 35% and 10-year overall survival was 26%. Prognostic factors were histology of renal cell carcinoma (G1, 2 group vs. G3 group; 2-year survival rate was 69% and 20% respectively, p=0.023) and disease-free interval (less than 24 months vs. more than 24 months; 5-year disease-free survival rate was 22% and 75% respectively, p=0.019) in univariate analysis. Only disease-free interval showed significant difference (p=0.037) in multivariate analysis. This study demonstrated that aggressive surgical resection of pulmonary metastasis from renal cell carcinoma leads to the good prognosis, especially in cases with a long disease-free interval.
authors.affiliation: Department of Thoracic Surgery, Sapporo City General Hospital, Sapporo, Japan.
authors.forename: Motoki
authors.initials: M
authors.lastname: Sakuraba
authors.forename: Akihiko
authors.initials: A
authors.lastname: Tanaka
authors.forename: Taijiro
authors.initials: T
authors.lastname: Mishina
authors.forename: Toshimori
authors.initials: T
authors.lastname: Seki
mesh_terms: D000328:Adult; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000473:pathology*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D059146:Metastasectomy; D008875:Middle Aged; D011013:Pneumonectomy; D011379:Prognosis; D012189:Retrospective Studies