title: [MicroRNAs and lung cancer].
abstract: MicroRNAs (miRNAs) are a class of non-coding RNAs that hybridize to mRNAs and induce either translation repression or mRNA cleavage. Patterns of altered miRNA expression in cancer may work as molecular biomarkers for tumor diagnosis, prognosis of disease-specific outcomes, and prediction of therapeutic responses. In addition, miRNAs can serve as specific targets for gene therapies. This review summarizes the current knowledge of miRNAs and their roles in lung cancer.
authors.affiliation: Department of Medical Genetic, Faculty of Meram Medicine, Necmettin Erbakan University, Konya, Turkey. agzamani@yahoo.com
authors.forename: Ayşe Gül
authors.initials: AG
authors.lastname: Zamani
authors.forename: Adil
authors.initials: A
authors.lastname: Zamani
mesh_terms: D014408:Biomarkers, Tumor; D005786:Gene Expression Regulation; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000235:genetics*; D035683:MicroRNAs / Q000235:genetics* / Q000378:metabolism; D011379:Prognosis; D012333:RNA, Messenger / Q000235:genetics
chemical_list: D014408:Biomarkers, Tumor; D035683:MicroRNAs; D012333:RNA, Messenger