title: Primary pleomorphic malignant fibrous histiocytoma of the heart.
abstract: Primary pleomorphic malignant fibrous histiocytoma of the heart is rare. The present study was performed to study the clinical and pathological features of the disease. We describe two rare cases of primary cardiac malignant fibrous histiocytoma and review the published individual data of the patients. Both patients complained of dyspnea, and underwent palliative tumor resection. However, they died several months after surgery. A thorough literature review with clinical presentations, diagnostic features, treatment, and outcomes was done. We have for the first time analyzed the factors related to the survival of malignant fibrous histiocytoma. It is usually difficult to make an appropriate preoperative diagnosis. Despite complete surgical resection and aggressive chemotherapy and radiotherapy, the prognosis is still poor.
authors.affiliation: Department of Pathology, the Affiliated Hospital of Medical College, Qingdao University, Qingdao, PR China.
authors.forename: Jigang
authors.initials: J
authors.lastname: Wang
authors.forename: Yanxia
authors.initials: Y
authors.lastname: Jiang
authors.forename: Yuewei
authors.initials: Y
authors.lastname: Wang
authors.forename: Wenjuan
authors.initials: W
authors.lastname: Yu
authors.forename: Peng
authors.initials: P
authors.lastname: Zhao
authors.forename: Yujun
authors.initials: Y
authors.lastname: Li
authors.forename: Dongliang
authors.initials: D
authors.lastname: Lin
authors.forename: Fangjie
authors.initials: F
authors.lastname: Xin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004417:Dyspnea / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006338:Heart Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D051677:Histiocytoma, Malignant Fibrous / Q000175:diagnosis / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016019:Survival Analysis
keywords: Heart neoplasms; Malignant fibrous histiocytoma; Undifferentiated pleomorphic sarcoma