title: A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection.
abstract: Stroke is the leading cause of disability in the USA. Rapid, reliable diagnosis via a point-of-care blood test may facilitate earlier treatment to reduce disability. We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers.
authors.affiliation: Department of Chemistry, University of Cincinnati, Cincinnati, OH, 45221, USA.
authors.forename: Phanichand
authors.initials: P
authors.lastname: Kodali
authors.forename: Julio A
authors.initials: JA
authors.lastname: Landero-Figueroa
authors.forename: Joseph
authors.initials: J
authors.lastname: Caruso
authors.forename: Opeolu
authors.initials: O
authors.lastname: Adeoye
mesh_terms: D015415:Biomarkers / Q000097:blood*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D006801:Humans; D021241:Spectrometry, Mass, Electrospray Ionization / Q000379:methods*; D020521:Stroke / Q000097:blood*
chemical_list: D015415:Biomarkers