title: Copper-catalyzed decarboxylative coupling of alkynyl carboxylates with 1,1-dibromo-1-alkenes.
abstract: A copper-catalyzed decarboxylative coupling reaction of potassium alkynyl carboxylates with 1,1-dibromo-1-alkenes was developed for the synthesis of unsymmetrical 1,3-diyne and 1,3,5-triyne derivatives. Diverse aryl, alkenyl, alkynyl, and alkyl substituted 1,1-dibromo-1-alkenes can react smoothly with aryl and alkyl substituted propiolates to produce unsymmetrical 1,3-diynes and 1,3,5-triynes with high selectivity and good functional group compatibility.
authors.affiliation: Anhui Province Key Laboratory of Biomass Clean Energy, Collaborative Innovative Center of Chemistry for Energy Materials, and Department of Chemistry, University of Science and Technology of China, Hefei 230026, PR China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Huang
authors.forename: Rui
authors.initials: R
authors.lastname: Shang
authors.forename: Zi-Rong
authors.initials: ZR
authors.lastname: Zhang
authors.forename: Xiao-Dan
authors.initials: XD
authors.lastname: Tan
authors.forename: Xiao
authors.initials: X
authors.lastname: Xiao
authors.forename: Yao
authors.initials: Y
authors.lastname: Fu
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry; D002264:Carboxylic Acids / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D003300:Copper / Q000737:chemistry*; D003653:Decarboxylation; D006842:Hydrocarbons, Brominated / Q000737:chemistry*; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry; D010618:Phenanthrolines / Q000737:chemistry
chemical_list: D000475:Alkenes; D000480:Alkynes; D002264:Carboxylic Acids; D006842:Hydrocarbons, Brominated; D009942:Organometallic Compounds; D010618:Phenanthrolines; D003300:Copper; C002701:neocuproine