title: Defined polymer-peptide conjugates to form cell-instructive starPEG-heparin matrices in situ.
abstract: Poly(ethylene glycol)-peptide- and glycosaminoglycan-peptide conjugates obtained by a regio-selective amino acid protection strategy are converted into cell-instructive hydrogel matrices capable of inducing morphogenesis in embedded human vascular endothelial cells and dorsal root ganglia.
authors.affiliation: Leibniz Institute of Polymer Research Dresden e.V., Max Bergmann Center of Biomaterials Dresden, Hohe Str. 6, 01069 Dresden, Germany.
authors.forename: Mikhail V
authors.initials: MV
authors.lastname: Tsurkan
authors.forename: Karolina
authors.initials: K
authors.lastname: Chwalek
authors.forename: Silvana
authors.initials: S
authors.lastname: Prokoph
authors.forename: Andrea
authors.initials: A
authors.lastname: Zieris
authors.forename: Kandice R
authors.initials: KR
authors.lastname: Levental
authors.forename: Uwe
authors.initials: U
authors.lastname: Freudenberg
authors.forename: Carsten
authors.initials: C
authors.lastname: Werner
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology*; D006493:Heparin / Q000737:chemistry*; D061307:Human Umbilical Vein Endothelial Cells / Q000166:cytology / Q000187:drug effects; D006801:Humans; D010455:Peptides / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D010455:Peptides; D013438:Sulfhydryl Compounds; D011092:Polyethylene Glycols; D006493:Heparin