title: [High dose rate prostate brachytherapy].
abstract: This article aims at presenting the interest of high dose rate brachytherapy in the radiation treatment of prostatic adenocarcinoma. We will discuss successively the biological and dosimetric specificity of brachytherapy for this particular cancer. Afterwards, we will review the main phase II and III studies, the therapeutic indications in the daily practice from the evidence based medicine as well as the techniques of external beam radiation therapy for the same indications. Finally, the principal avenues of development will be discussed.
authors.affiliation: Département universitaire de radiothérapie et curiethérapie, centre Oscar-Lambret, 3, rue Frédéric-Combemale, 59000 Lille, France. p-nickers@o-lambret.fr
authors.forename: P
authors.initials: P
authors.lastname: Nickers
authors.forename: P
authors.initials: P
authors.lastname: Blanchard
authors.forename: J-M
authors.initials: JM
authors.lastname: Hannoun-Lévi
authors.forename: A
authors.initials: A
authors.lastname: Bossi
authors.forename: O
authors.initials: O
authors.lastname: Chapet
authors.forename: S
authors.initials: S
authors.lastname: Guérif
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D001918:Brachytherapy / Q000009:adverse effects / Q000379:methods*; D017322:Clinical Trials, Phase II as Topic; D017326:Clinical Trials, Phase III as Topic; D003131:Combined Modality Therapy; D019317:Evidence-Based Medicine; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000209:etiology / Q000517:prevention & control; D011836:Radiation Tolerance; D011874:Radiometry; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D061089:Radiotherapy, Image-Guided; D018570:Risk Assessment; D014463:Ultrasonography
chemical_list: D018931:Antineoplastic Agents, Hormonal