title: Coupled transport protein systems.
abstract: This set of animated lessons provides examples of how transport proteins interact in coupled systems to produce physiologic effects. The gastric pumps animation depicts the secretion of hydrochloric acid into the gastric lumen. The animation called glucose absorption depicts glucose absorption by intestinal epithelial cells. The CFTR animation explains how the cystic fibrosis conductance transmembrane regulator (CFTR) functions as a key component of a coupled system of transport proteins that clears the pulmonary system of mucus and inhaled particulates. These animations serve as valuable resources for any collegiate-level course that describes these processes. Courses that might use them include introductory biology, biochemistry, biophysics, cell biology, pharmacology, and physiology.
authors.affiliation: West Virginia School of Osteopathic Medicine, 400 North Lee Street, Lewisburg, WV 24901, USA. jthatcher@osteo.wvsom.edu
authors.forename: Jack D
authors.initials: JD
authors.lastname: Thatcher
mesh_terms: D001692:Biological Transport / Q000502:physiology*; D002352:Carrier Proteins / Q000378:metabolism*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D006851:Hydrochloric Acid / Q000378:metabolism; D008954:Models, Biological; D013664:Teaching Materials
chemical_list: D002352:Carrier Proteins; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D005947:Glucose; D006851:Hydrochloric Acid