title: Antimicrobial resistance of abnormal vaginal discharges microorganisms in Ouagadougou, Burkina Faso.
abstract: OBJECTIVE
  To assess the prevalence of bacterial strains and fungal strains infecting the vaginal tract and test their sensitivity to antibiotics in women attending Saint Camille Medical Centre in Ouagadougou.
  
  
  METHODS
  From January 2008 to December 2009, a total of 2 000 vaginal swabs were cultivated for bacterial and fungal identification and isolation. Furthermore, bacterial strains were tested for their susceptibility to several antibiotics used in routine in the centre.
  
  
  RESULTS
  The results revealed that microbial isolation and identification was attempted for 1 536/2 000 sample, a positivity rate of 76.80%. Candida albicans (48.76%), followed by Escherichia coli (16.67%), Streptococcus agalactiae (8.14%) and Staphylococcus aureus (7.55%) were the major agents of genital tract infections in patients. Mycoplasma hominis and Ureaplasma urealyticum combined accounted for less than 7%. Trichomonas vaginalis was identified in 1.04% cases. The antimicrobial tests revealed that the microorganisms developed resistance to several antibiotics including beta lactams. However, antibiotics such as cefamenzol, ciprofloxacin and norfloxacin were still active on these bacteria.
  
  
  CONCLUSIONS
  The results reveal that many sexually active women are infected by one or more microbial pathogens, probably because of the lack of hygiene or the adoption of some risky behaviors, such as not using condoms or having multiple sexual partners. Efforts should be made to address these points in the country.
authors.affiliation: Centre de Recherche Biomoléculaire Pietro Annigoni (CERBA), Ouagadougou, Burkina Faso ; Ecole Supérieure des Techniques Alimentaires et Biologiques (ESTBA-UL), Université de Lomé, Togo.
authors.forename: Simplice D
authors.initials: SD
authors.lastname: Karou
authors.forename: Florencia
authors.initials: F
authors.lastname: Djigma
authors.forename: Tani
authors.initials: T
authors.lastname: Sagna
authors.forename: Christelle
authors.initials: C
authors.lastname: Nadembega
authors.forename: Moctar
authors.initials: M
authors.lastname: Zeba
authors.forename: Aboudoulaye
authors.initials: A
authors.lastname: Kabre
authors.forename: Kokou
authors.initials: K
authors.lastname: Anani
authors.forename: Djeneba
authors.initials: D
authors.lastname: Ouermi
authors.forename: Charlemagne
authors.initials: C
authors.lastname: Gnoula
authors.forename: Virginio
authors.initials: V
authors.lastname: Pietra
authors.forename: Salvatore
authors.initials: S
authors.lastname: Pignatelli
authors.forename: Jacques
authors.initials: J
authors.lastname: Simpore
mesh_terms: D000328:Adult; D001419:Bacteria / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification; D002050:Burkina Faso / Q000453:epidemiology; D002176:Candida albicans / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification; D015331:Cohort Studies; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D019522:Vaginal Discharge / Q000453:epidemiology* / Q000382:microbiology*; D055815:Young Adult
keywords: Abnormal vaginal discharge; Antibiotics; Antimicrobial resistance; Bacteria; Fungal strain; Genital infections; Mycoplasma; Vaginal infection