title: Electronic laboratory notebooks progress and challenges in implementation.
abstract: Electronic laboratory notebooks (ELNs) are increasingly replacing paper notebooks in life science laboratories, including those in industry, academic settings, and hospitals. ELNs offer significant advantages over paper notebooks, but adopting them in a predominantly paper-based environment is usually disruptive. The benefits of ELN increase when they are integrated with other laboratory informatics tools such as laboratory information management systems, chromatography data systems, analytical instrumentation, and scientific data management systems, but there is no well-established path for effective integration of these tools. In this article, we review and evaluate some of the approaches that have been taken thus far and also some radical new methods of integration that are emerging.
authors.affiliation: Indiana University, Bloomington, IN 47405, USA. hari_machina@hotmail.com
authors.forename: Hari K
authors.initials: HK
authors.lastname: Machina
authors.forename: David J
authors.initials: DJ
authors.lastname: Wild
mesh_terms: D000818:Animals; D057205:Automation, Laboratory / Q000295:instrumentation*; D002984:Clinical Laboratory Information Systems / Q000295:instrumentation*; D055615:Electrical Equipment and Supplies; D004582:Electronics, Medical / Q000639:trends; D006801:Humans; D008905:Minicomputers / Q000706:statistics & numerical data* / Q000639:trends*; D012106:Research
keywords: analytical and purification; chemistry informatics laboratory information managements systems (LIMS); chromatography; informatics and software; laboratory management