title: Oseltamivir (Tamiflu)-induced bilateral acute angle closure glaucoma and transient myopia.
abstract: A 27-year-old woman developed bilateral acute angle closure glaucoma (AACG) and transient myopia after taking oseltamivir for four days. On the fourth day, she received systemic and topical intraocular pressure (IOP)-lowering agents, and IOP decreased in both eyes. However, her visual acuity was unchanged. A myopic shift of -5.25 D OD and -5.0 D OS was estimated to have occurred in the acute phase. A-scan ultrasonography and Pentacam showed markedly shallow anterior chambers and increased lens thickness. Ultrasound biomicroscopy revealed an annular ciliochoroidal effusion with forward displacement of the lens-iris diaphragm. Ciliochoroidal effusion and transient myopia were resolved after discontinuation of oseltamivir.
authors.affiliation: Department of Ophthalmology, Pusan National University School of Medicine, Busan, Korea.
authors.forename: Ji Woong
authors.initials: JW
authors.lastname: Lee
authors.forename: Ji Eun
authors.initials: JE
authors.lastname: Lee
authors.forename: Hee Young
authors.initials: HY
authors.lastname: Choi
authors.forename: Jong Soo
authors.initials: JS
authors.lastname: Lee
mesh_terms: D000208:Acute Disease; D000328:Adult; D000998:Antiviral Agents / Q000009:adverse effects; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D033401:Microscopy, Acoustic; D009216:Myopia / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D053139:Oseltamivir / Q000009:adverse effects*; D014792:Visual Acuity / Q000502:physiology*
chemical_list: D000998:Antiviral Agents; D053139:Oseltamivir