title: Comparison of the utility of everyday memory test and the Alzheimer's Disease Assessment Scale-Cognitive part for evaluation of mild cognitive impairment and very mild Alzheimer's disease.
abstract: OBJECTIVE
  The purpose of this study was to compare the utility of the Rivermead Behavioural Memory Test (RBMT) and the Alzheimer's Disease Assessment Scale-Cognitive part (ADAS-Cog) for the evaluation of mild cognitive impairment (MCI) or very mild Alzheimer's disease (AD).
  
  
  METHODS
  The discriminative abilities of RBMT and ADAS-Cog were compared in the very early stage of AD or MCI patients. Furthermore, we evaluated the difference in both RBMT score and ADAS-Cog score between different severities.
  
  
  RESULTS
  Evident superiority in the false negative rate was observed in RBMT over ADAS-Cog in MCI or very mild AD. In addition, 86.7% of the subjects overlooked by ADAS-Cog were correctly detected by RBMT profile score. However, the RBMT score falls in the very early stages and the range of the RBMT score is rather narrow. As a result, it is difficult to evaluate status and follow the progression in severer cases. In contrast to RBMT, the ADAS-Cog score has a wide range and can evaluate and follow the severity in more severe cases.
  
  
  CONCLUSIONS
  RBMT is more useful than ADAS-Cog in evaluating patients with MCI or very mild AD.
authors.affiliation: Department of Psychiatry, Osaka University Health Care Center, Osaka, Japan.
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Adachi
authors.forename: Shunichiro
authors.initials: S
authors.lastname: Shinagawa
authors.forename: Kenjiro
authors.initials: K
authors.lastname: Komori
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Toyota
authors.forename: Takaaki
authors.initials: T
authors.lastname: Mori
authors.forename: Teruhisa
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Naomi
authors.initials: N
authors.lastname: Sonobe
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Kashibayashi
authors.forename: Tomohisa
authors.initials: T
authors.lastname: Ishikawa
authors.forename: Ryuji
authors.initials: R
authors.lastname: Fukuhara
authors.forename: Manabu
authors.initials: M
authors.lastname: Ikeda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000523:psychology*; D060825:Cognitive Dysfunction / Q000175:diagnosis* / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics