title: Motion artefact in voltage-sensitive fluorescent dye emission during repeated ischemia of isolated heart.
abstract: Motion artefact (MA) in voltage-sensitive fluorescent signals causes significant debasement of action potential. During ischemia and reperfusion in isolated rabbit heart, this artefact develops in a manner which may be described by the time of its onset, level, and shape. The MA during ischemia: (a) may become substantial with approximately two minutes delay after establishing global ischemia; (b) may be almost twice as high as the physiological action potential and decreases both with time and repetition of ischemia; (c) the MA shape is unpredictable and depends on individual rabbit.
authors.affiliation: Department of Biomedical Engineering Faculty of Electrical Engineering and Communication, University of Technology, Brno, Czech Republic. xjanou12@stud.feec.vutbr.cz
authors.forename: O
authors.initials: O
authors.lastname: Janoušek
authors.forename: J
authors.initials: J
authors.lastname: Kolářová
authors.forename: M
authors.initials: M
authors.lastname: Ronzhina
authors.forename: M
authors.initials: M
authors.lastname: Nováková
authors.forename: I
authors.initials: I
authors.lastname: Provazník
mesh_terms: D000200:Action Potentials; D000818:Animals; D016477:Artifacts; D005456:Fluorescent Dyes; D066298:In Vitro Techniques; D015428:Myocardial Reperfusion Injury / Q000175:diagnosis* / Q000503:physiopathology; D010477:Perfusion; D011237:Predictive Value of Tests; D011726:Pyridinium Compounds; D011817:Rabbits; D013997:Time Factors; D056969:Voltage-Sensitive Dye Imaging / Q000379:methods*
chemical_list: D005456:Fluorescent Dyes; D011726:Pyridinium Compounds; C050019:1-(3-sulfonatopropyl)-4-(beta)(2-(di-n-butylamino)-6-naphthylvinyl)pyridinium betaine