title: Technologies for detecting metals in single cells.
abstract: In order to fully understand the metallomics of an organism, it is essential to know how much metal is present in each cell and, ideally, to know both the spatial and chemical distributions of each metal (i.e., where within the cell is a metal found, and in what chemical form). No single technique provides all of this information. This chapter reviews the various methods that can be used and the strengths and weaknesses of each.
authors.affiliation: Departments of Chemistry and Biophysics, University of Michigan, 930 N. University Avenue, Ann Arbor, MI, 48109-1055, USA, jeph@umich.edu.
authors.forename: James E
authors.initials: JE
authors.lastname: Penner-Hahn
mesh_terms: D008670:Metals / Q000737:chemistry
chemical_list: D008670:Metals