title: Lactate dehydrogenase isoenzyme patterns in auricular pseudocyst fluid.
abstract: OBJECTIVE
  We investigated lactate dehydrogenase isoenzyme patterns in the cyst fluid of auricular pseudocysts and autogenous blood, to assist the diagnosis of auricular pseudocyst.
  
  
  METHODS
  Twenty patients with auricular pseudocysts participated in this study conducted in Kaohsiung Medical University Hospital between February 2007 and June 2010. Patterns of lactate dehydrogenase in cyst fluid and autogenous blood were analysed.
  
  
  RESULTS
  Levels of lactate dehydrogenase 1 and 2 were lower in auricular pseudocysts than in autogenous blood, whereas levels of lactate dehydrogenase 4 and 5 were higher; this difference was statistically significant (p < 0.001).
  
  
  CONCLUSIONS
  Lactate dehydrogenase isoenzyme patterns in auricular pseudocyst fluid indicated higher percentage distributions of lactate dehydrogenase 4 and 5 and lower percentage distributions of lactate dehydrogenase 1 and 2. An effective laboratory method of evaluating the different lactate dehydrogenase isoenzyme components was developed; this method may improve the accuracy of auricular pseudocyst diagnosis.
authors.affiliation: Department of Otolaryngology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
authors.forename: P-P
authors.initials: PP
authors.lastname: Chen
authors.forename: S-M
authors.initials: SM
authors.lastname: Tsai
authors.forename: H-M
authors.initials: HM
authors.lastname: Wang
authors.forename: L-F
authors.initials: LF
authors.lastname: Wang
authors.forename: C-Y
authors.initials: CY
authors.lastname: Chien
authors.forename: N-C
authors.initials: NC
authors.lastname: Chang
authors.forename: K-Y
authors.initials: KY
authors.lastname: Ho
mesh_terms: D000328:Adult; D020420:Cyst Fluid / Q000737:chemistry* / Q000201:enzymology*; D003560:Cysts / Q000737:chemistry* / Q000201:enzymology*; D054644:Ear Auricle; D004427:Ear Diseases / Q000201:enzymology*; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000032:analysis; D007770:L-Lactate Dehydrogenase / Q000032:analysis*; D008297:Male; D011446:Prospective Studies
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase