title: Beyond the sympathetic tone: the new brown fat activators.
abstract: If we could avoid the side effects associated with global sympathetic activation, activating brown adipose tissue to increase thermogenesis would be a safe way to lose weight. The discovery of adrenergic-independent brown fat activators opens the prospect of developing this alternative way to efficiently and safely induce negative energy balance.
authors.affiliation: Departament de Bioquimica i Biologia Molecular, Institute of Biomedicine (IBUB), University of Barcelona, and CIBER Fisiopatologia de la Obesidad y Nutrición, Av Diagonal 643, 08028 Barcelona, Catalonia, Spain. fvillarroya@ub.edu
authors.forename: Francesc
authors.initials: F
authors.lastname: Villarroya
authors.forename: Antonio
authors.initials: A
authors.lastname: Vidal-Puig
mesh_terms: D002001:Adipose Tissue, Brown / Q000378:metabolism*; D000818:Animals; D001835:Body Weight / Q000502:physiology; D004734:Energy Metabolism / Q000502:physiology*; D006801:Humans; D013564:Sympathetic Nervous System / Q000378:metabolism / Q000502:physiology*; D022722:Thermogenesis / Q000502:physiology*; D015431:Weight Loss / Q000502:physiology