title: Survival analysis of women with cervical cancer treated at a referral hospital for oncology in Espírito Santo State, Brazil, 2000-2005.
abstract: Uterine cervical cancer is a leading cause of death from cancer in the female population worldwide. The aim of this study was to analyze survival of women with cervical cancer treated at the Santa Rita de Cássia Hospital/Women's Association for Cancer Education and Control (HSRC/AFECC) in Espírito Santo State, Brazil, from 2000 to 2005 and to describe associated prognostic factors. This was a cohort study using retrospective secondary data with a sample of 964 cases. The Kaplan-Meier curve and Cox model were used to evaluate survival and for multiple logistic analysis. There were 421 deaths (43.6%) during the minimum 5-year follow-up, with an overall 5-year survival of 58.8%. Risk factors were place of residence in the Serrana Region of the State (HR: 1.94; 95%CI: 1.09-3.45) and advanced staging. Women with stages III and IV at diagnosis showed an increased risk of 4.33 (95%CI: 3.00-6.24) and 15.40 (95%CI: 9.72-24.39), respectively, for lower survival when compared to stage I. The results show that early diagnosis and treatment are essential for reducing mortality from cervical cancer.
authors.affiliation: Centro Universitário Norte do Espírito Santo, Universidade Federal do Espírito Santo, Vitória, Brasil. keilamascarello@gmail.com
authors.forename: Keila Cristina
authors.initials: KC
authors.lastname: Mascarello
authors.forename: Eliana
authors.initials: E
authors.lastname: Zandonade
authors.forename: Maria Helena Costa
authors.initials: MH
authors.lastname: Amorim
mesh_terms: D000328:Adult; D001938:Brazil / Q000453:epidemiology; D002294:Carcinoma, Squamous Cell / Q000401:mortality*; D004522:Educational Status; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D008875:Middle Aged; D016019:Survival Analysis; D002583:Uterine Cervical Neoplasms / Q000401:mortality*; D016387:Women's Health