title: Blastic plasmacytoid dendritic cell neoplasm.
abstract: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare haematological malignancy that originates from the precursors of plasmacytoid dendritic cells. It commonly presents with findings isolated to the skin although it usually progresses to a leukaemic phase. It has a poor prognosis but is curable, particularly in younger patients treated with allogeneic bone marrow transplantation. We report a case of a 79-year old man who had 6 months of progressive, asymptomatic BPDCN manifestations limited to the skin, before developing a leukaemic phase.
authors.affiliation: Department of Dermatology, Waikato Hospital, Hamilton, Waikato, New Zealand. davidlim79@gmail.com
authors.forename: David
authors.initials: D
authors.lastname: Lim
authors.forename: Hugh
authors.initials: H
authors.lastname: Goodman
authors.forename: Marius
authors.initials: M
authors.lastname: Rademaker
authors.forename: Duncan
authors.initials: D
authors.lastname: Lamont
authors.forename: Anthony
authors.initials: A
authors.lastname: Yung
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003713:Dendritic Cells / Q000473:pathology*; D017809:Fatal Outcome; D019337:Hematologic Neoplasms / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000305:Adrenal Cortex Hormones