title: Opportunistic viral infections in intestinal transplantation.
abstract: Intestinal transplantation (IT) has become a standard treatment for patients with intestinal failure and complications of parenteral nutrition. The pool of intestinal transplant recipients has been slowly growing over the last two decades. Of the 2191 ITs performed between 1 January 1990 and 31 March 2012, 50.5% were children less than 10 years of age. Survival rates at 1, 5 and 10 years have been reported to be 78.5, 58.2 and 47%, respectively. IT restores organ functions, but it is associated with complications, with infections representing the major cause of morbidity and mortality in this population.
authors.affiliation: Division of Infectious Diseases, Transplant Infectious Diseases Program, University of Nebraska Medical Center, Omaha, NE 68198-5400, USA. dflorescu@unmc.edu
authors.forename: Diana F
authors.initials: DF
authors.lastname: Florescu
authors.forename: Alan N
authors.initials: AN
authors.lastname: Langnas
authors.forename: Uriel
authors.initials: U
authors.lastname: Sandkovsky
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007422:Intestines / Q000473:pathology / Q000637:transplantation* / Q000821:virology*; D008297:Male; D009894:Opportunistic Infections / Q000209:etiology / Q000401:mortality / Q000517:prevention & control / Q000821:virology*; D010288:Parenteral Nutrition; D016019:Survival Analysis; D016378:Tissue Transplantation / Q000009:adverse effects / Q000401:mortality; D014777:Virus Diseases / Q000209:etiology / Q000401:mortality / Q000517:prevention & control / Q000821:virology*
chemical_list: D000998:Antiviral Agents