title: Surgery for pulmonary malignancies in patients with a previous history of head and neck squamous cell carcinoma.
abstract: OBJECTIVE
  To examine the perioperative and long-term outcomes of surgery for malignancies of the lungs in patients with a history of head and neck squamous cell carcinoma (HNSCC) and to evaluate the risk factors associated with postoperative complications.
  
  
  METHODS
  The data of 39 patients with a history of HNSCC who underwent pulmonary resection were reviewed. The perioperative and long-term outcomes were analyzed.
  
  
  RESULTS
  Eight patients (21%) had difficult airways, and nine patients (23%) developed postoperative complications. A low body mass index (<18.5), a history of malignancy besides HNSCC and chronic obstructive pulmonary disease were each found to be significantly associated with the development of postoperative complications. The 5-year survival rate of all patients was 80%.
  
  
  CONCLUSIONS
  The airway management of patients with a history of HNSCC should be carefully undertaken. Preoperative assessment of their nutritional status and careful prevention of air leakage during surgery are important. Because favorable outcomes can be achieved, aggressive surgical management should be considered for the treatment of pulmonary malignancies in patients with a history of HNSCC.
authors.affiliation: Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, L5-2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors.forename: Ryu
authors.initials: R
authors.lastname: Kanzaki
authors.forename: Masayoshi
authors.initials: M
authors.lastname: Inoue
authors.forename: Masato
authors.initials: M
authors.lastname: Minami
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Shintani
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Nakagiri
authors.forename: Soichiro
authors.initials: S
authors.lastname: Funaki
authors.forename: Mikihiko
authors.initials: M
authors.lastname: Kogo
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Yura
authors.forename: Hidenori
authors.initials: H
authors.lastname: Inohara
authors.forename: Noriyoshi
authors.initials: N
authors.lastname: Sawabata
authors.forename: Meinoshin
authors.initials: M
authors.lastname: Okumura
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D058109:Airway Management; D057868:Anastomotic Leak / Q000517:prevention & control; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D019990:Perioperative Care; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology; D029424:Pulmonary Disease, Chronic Obstructive; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome; D055815:Young Adult