title: Relationship between inflammatory markers of cardiovascular disease and VO2peak in asymptomatic females.
abstract: OBJECTIVE
  The objective of this study was to investigate the relationship between inflammatory markers of cardiovascular disease (IL-6 and acute-phase reactants) and VO2peak in asymptomatic females.
  
  
  METHODS
  Study subjects were females not affected by coronary heart diseases. Forty healthy female subjects (age, 45±4.2 years; height, 161±3.5 cm; weight, 65±3.1 kg; history of regular physical activity, 5.2±0.45 years) participated in this study
  
  
  RESULTS
  Analysis of data was carried out by Pearson's correlation. Statistical analysis of data indicated a negative significant relationship between IL-6 and VO2peak (r=-0.48, r2=0.23, P<0.048), CRP and VO2peak (r=-0.40, r2= 0.16, P<0.002), fibrinogen and VO2peak (r=-0.42, r2=0.17, P<0.001), and WBC and VO2peak (r=-0.22, r2=0.04, P<0.044).
  
  
  CONCLUSIONS
  In conclusion higher circulating levels of IL-6, CRP and fibrinogen are associated with lower VO2peak in females.
authors.affiliation: Department of Exercise Physiology, Tehran University, Tehran, Iran. siminomran@ut.ac.ir
authors.forename: F
authors.initials: F
authors.lastname: Omran Simin
authors.forename: Z
authors.initials: Z
authors.lastname: Narges
authors.forename: A
authors.initials: A
authors.lastname: Sajad
authors.forename: Y
authors.initials: Y
authors.lastname: Parisa
authors.forename: F
authors.initials: F
authors.lastname: Omrani Vahid
mesh_terms: D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000378:metabolism; D002318:Cardiovascular Diseases / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D007958:Leukocyte Count; D008055:Lipids / Q000097:blood; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology*; D017697:Premenopause
chemical_list: D015415:Biomarkers; D015850:Interleukin-6; D008055:Lipids; D005340:Fibrinogen; D002097:C-Reactive Protein