title: Diagnostic methods and management strategies of herpes simplex and herpes zoster infections.
abstract: Herpes infections are extremely prevalent in the adult population. Recognizing early signs and symptoms is essential to provide effective treatment. The immunocompromised population presents treatment challenges requiring prolonged antiviral therapy and more frequent recurrences. Viral culture is often considered the gold standard diagnostic technique; however, polymerase chain reaction (PCR) should be done in tandem with culture especially for varicella zoster virus infections. Antivirals can decrease viral shedding, recurrences of herpes simplex, and hasten healing of herpes zoster. Herpes virus can be a challenging entity to treat with significant morbidity (both physically and psychologically).
authors.affiliation: Department of Dermatology, Saint Louis University, 1755 South Grand Boulevard 4th Floor, Saint Louis, MO 63104, USA.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Frisch
authors.forename: Aibing Mary
authors.initials: AM
authors.lastname: Guo
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use; D001706:Biopsy; D003937:Diagnosis, Differential; D006561:Herpes Simplex / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology; D006562:Herpes Zoster / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology; D014645:Herpesvirus 3, Human; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology; D016133:Polymerase Chain Reaction; D018139:Simplexvirus; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents