title: Parental functioning improves the developmental quotient of pediatric liver transplant recipients.
abstract: Psychomotor development in pediatric liver transplant (LT) recipients depends on several factors. Our aim was to evaluate the importance of parental involvement and family dynamics on psychomotor development by assessing (i) children and parents individually, (ii) the parent-child relationship, and (iii) the correlation between parental functioning and patient outcome, all before and after LT. Age-appropriate scales were used before and after LT. Twenty-one patients, 19 mothers, and 16 fathers were evaluated. Developmental quotient (DQ): No subjects scored in the "very good" range. The proportion of children with deficits increased from LT to two yr: 17.6% vs. 28.6%. Subjects 0-2 yr were more likely to have normal DQ at transplant (66.7% vs. 50% for older children). Abnormal DQ was more prevalent two yr post-LT in children older at LT (p = 0.02). The mother-child relationship was normal in 59% of families pre-LT and in 67% at two yr. The relationship was more favorable when the child received a transplant as an infant (p = 0.014 at 12 months post-LT). Normal DQ was associated with higher maternal global functioning score pre-LT (p = 0.03). Paternal performance scores were higher than maternal scores. Children transplanted after two yr of age suffer greater long-term deficits than those transplanted as infants.
authors.affiliation: Department of Pediatrics, Children's Hospital of Geneva, University Hospitals of Geneva, 6 Rue Willy-Donzé, Geneva, Switzerland. Klara.PosfayBarbe@hcuge.ch
authors.forename: Klara M
authors.initials: KM
authors.lastname: Posfay-Barbe
authors.forename: Rémy P
authors.initials: RP
authors.lastname: Barbe
authors.forename: Renate
authors.initials: R
authors.lastname: Wetterwald
authors.forename: Dominique C
authors.initials: DC
authors.lastname: Belli
authors.forename: Valérie A
authors.initials: VA
authors.lastname: McLin
mesh_terms: D000367:Age Factors; D002648:Child; D002657:Child Development; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000209:etiology; D005260:Female; D006801:Humans; D007223:Infant; D007361:Intelligence Tests; D017093:Liver Failure / Q000150:complications / Q000628:therapy*; D016031:Liver Transplantation; D008297:Male; D009034:Mother-Child Relations; D009035:Mothers / Q000523:psychology; D009048:Motor Skills; D009483:Neuropsychological Tests; D010290:Parents / Q000523:psychology*; D016896:Treatment Outcome