title: Ovarian damage after laparoscopic endometrioma excision might be related to the size of cyst.
abstract: OBJECTIVE
  To investigate the relationship between the size of an excised endometrioma and the magnitude of damage to the ovary after the surgery.
  
  
  METHODS
  A retrospective, controlled study.
  
  
  METHODS
  A university hospital.
  
  
  METHODS
  Eighty-five women with a history of laparoscopic excision of unilateral endometrioma who underwent in vitro fertilization (IVF).
  
  
  METHODS
  IVF-embryo transfer procedures.
  
  
  METHODS
  Antral follicle counts (AFC), number of dominant follicles (follicles ≥ 15 mm), and number of oocytes retrieved.
  
  
  RESULTS
  In the group with cyst diameters of ≥ 4 cm and group with cyst diameters of <4 cm, the AFC, number of dominant follicles, and number of oocytes retrieved were decreased in the operated ovaries when compared with those in intact ovaries; in the former group, a statistically significant reduction was observed. The differences of AFC, number of dominant follicles, and number of oocytes retrieved from both ovaries were further compared among the two groups: the decrease in the group with cyst diameters of ≥ 4 cm was higher than in the group with cyst diameters of <4 cm. After adjusting for age and AFC in intact ovaries, similar results were obtained, although AFC only showed a tendency. In addition, the receiver operating characteristic curve analysis revealed a statistically significant, positive correlation between the size of excised cysts and the incidence of fewer than four oocytes retrieved from an operated ovary.
  
  
  CONCLUSIONS
  The magnitude of the ovarian damage after laparoscopic endometrioma excision might be related to the size of cyst; the damage to ovaries is more severe when an endometrioma ≥ 4 cm is excised.
authors.affiliation: Center for Reproductive Medicine, Department of Gynecology and Obstetrics, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Tang
authors.forename: Shi-Ling
authors.initials: SL
authors.lastname: Chen
authors.forename: Xin
authors.initials: X
authors.lastname: Chen
authors.forename: Yu-Xia
authors.initials: YX
authors.lastname: He
authors.forename: De-Sheng
authors.initials: DS
authors.lastname: Ye
authors.forename: Wei
authors.initials: W
authors.lastname: Guo
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Zheng
authors.forename: Xin-Hong
authors.initials: XH
authors.lastname: Yang
mesh_terms: D000328:Adult; D002452:Cell Count; D004715:Endometriosis / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D005260:Female; D005307:Fertilization in Vitro / Q000706:statistics & numerical data; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects*; D006801:Humans; D007049:Iatrogenic Disease / Q000453:epidemiology; D007247:Infertility, Female / Q000453:epidemiology / Q000601:surgery / Q000628:therapy; D010535:Laparoscopy / Q000009:adverse effects*; D009929:Organ Size; D010048:Ovarian Cysts / Q000473:pathology; D010049:Ovarian Diseases / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D006080:Ovarian Follicle / Q000473:pathology; D010053:Ovary / Q000293:injuries* / Q000473:pathology; D010062:Ovulation Induction; D012189:Retrospective Studies
keywords: Endometrioma; IVF; excision; laparoscopy; retrieved oocytes