title: Poor outcome of HIV-infected patients with plasmablastic lymphoma: results from the German AIDS-related lymphoma cohort study.
abstract: Out of 302 AIDS-related lymphoma (ARL) patients enrolled in the German ARL cohort study, 18 patients had plasmablastic lymphoma (PBL). Twelve out of 18 patients (67%) have died with a median survival of 4 months (range 0-11 months). In univariate analysis, an intermediate or high international prognostic index score was associated with a significantly lower overall survival and progression-free survival. The predominant cause of death was progressive lymphoma (67%). Our data indicate that the outcome of AIDS-related PBL is still very poor.
authors.affiliation: First Department of Internal Medicine, University of Cologne, Cologne, Germany.
authors.forename: Philipp
authors.initials: P
authors.lastname: Schommers
authors.forename: Christoph
authors.initials: C
authors.lastname: Wyen
authors.forename: Marcus
authors.initials: M
authors.lastname: Hentrich
authors.forename: Daniel
authors.initials: D
authors.lastname: Gillor
authors.forename: Alexander
authors.initials: A
authors.lastname: Zoufaly
authors.forename: Bjoern
authors.initials: B
authors.lastname: Jensen
authors.forename: Johannes R
authors.initials: JR
authors.lastname: Bogner
authors.forename: Jan
authors.initials: J
authors.lastname: Thoden
authors.forename: Jan C
authors.initials: JC
authors.lastname: Wasmuth
authors.forename: Gerd
authors.initials: G
authors.lastname: Fätkenheuer
authors.forename: Christian
authors.initials: C
authors.lastname: Hoffmann
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D015331:Cohort Studies; D005858:Germany; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy / Q000401:mortality*; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000188:drug therapy / Q000209:etiology / Q000401:mortality*; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy / Q000209:etiology / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D012720:Severity of Illness Index