title: Clinically important interaction between metoprolol and propafenone.
authors.affiliation: Department of Clinical Pharmacology, University Hospital Ostrava, 17. Listopadu 1790 Ostrava, 708 52, Czech Republic. jankaduricova@seznam.cz
authors.forename: Jana
authors.initials: J
authors.lastname: Duricova
authors.forename: Ilona
authors.initials: I
authors.lastname: Perinova
authors.forename: Nikola
authors.initials: N
authors.lastname: Jurckova
authors.forename: Ivana
authors.initials: I
authors.lastname: Kacirova
authors.forename: Milan
authors.initials: M
authors.lastname: Grundmann
mesh_terms: D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology* / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001281:Atrial Fibrillation / Q000517:prevention & control; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics / Q000378:metabolism; D004232:Diuretics / Q000627:therapeutic use; D004347:Drug Interactions; D004417:Dyspnea / Q000139:chemically induced; D005221:Fatigue / Q000139:chemically induced; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D059065:Medication Reconciliation; D008790:Metoprolol / Q000031:analogs & derivatives / Q000097:blood* / Q000494:pharmacology* / Q000627:therapeutic use; D011405:Propafenone / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000889:Anti-Arrhythmia Agents; D000959:Antihypertensive Agents; D004232:Diuretics; C029504:alpha-hydroxymetoprolol; D011405:Propafenone; D019389:Cytochrome P-450 CYP2D6; D008790:Metoprolol