title: Incomplete Gardner's syndrome with blepharoptosis as the first symptom.
abstract: Gardner's syndrome (GS) is an autosomal dominant form of polyposis characterized by the presence of multiple polyps in the colon together with osseous tumors and soft-tissue tumors, such as epidermoid cysts and lipomas. An osteoma is a benign, osteogenic tumor and may be sporadic or related to GS. Here, we present a patient with a giant sino-orbital osteoma and blepharoptosis as the only symptom of incomplete GS. A 74-year-old woman, with no previous history of trauma or ophthalmic surgery, presented with a 2 years history of right blepharoptosis without diplopia. The results of slit-lamp and fundoscopic examination were normal. Computed tomography showed a giant sino-orbital osteoma. With suspicion for GS, we thoroughly examined the patient and found no soft-tissue tumors. Fifteen years ago, the patient, who had a family history of colonic polyposis, underwent right colectomy and chemotherapy for adenocarcinoma. We report a case of incomplete GS with blepharoptosis as the first symptom.
authors.affiliation: Department of Ophthalmology, Veroia General Hospital, Veroia, Greece, eirchat@yahoo.gr.
authors.forename: Irini P
authors.initials: IP
authors.lastname: Chatziralli
authors.forename: Leonidas
authors.initials: L
authors.lastname: Papazisis
authors.forename: Theodoros N
authors.initials: TN
authors.lastname: Sergentanis
mesh_terms: D000368:Aged; D001763:Blepharoptosis / Q000209:etiology*; D005260:Female; D005736:Gardner Syndrome / Q000473:pathology; D006801:Humans; D009918:Orbital Neoplasms / Q000150:complications*; D010016:Osteoma / Q000150:complications*; D010255:Paranasal Sinus Neoplasms / Q000150:complications*