title: The first case of Horn Kolb Syndrome in Turkey, diagnosed prenatally at the 23(rd) week of a pregnancy: A very rare and unusual case far from the original geography.
abstract: BACKGROUND
  The aim of this report was to evaluate and announce the first documented appearance of Horn Kolb syndrome in Turkey.
  
  
  METHODS
  Acheiropodia (Horn Kolb Syndrome) is the bilateral congenital amputation of the distal parts of the 4 extremities. It is an autosomal recessive developmental disorder. The characteristic features are amputation of the upper and lower extremities with aplasia of the hands and feet. The disorder affects only the extremities without other systemic manifestations. In this report, we present the first known case of Horn Kolb syndrome in Turkey, along with the diagnostic features.
  
  
  CONCLUSIONS
  Severe dysmorphic skeletal anomalies should be excluded as soon as the earlier gestational weeks in every pregnancy by visualizing all 4 limbs of the fetus in routine prenatal ultrasound screening.
authors.affiliation: Department of Obstetrics and Gynecology, University of Kafkas, Kars, Turkey.
authors.forename: Ismail
authors.initials: I
authors.lastname: Temur
authors.forename: Kahraman
authors.initials: K
authors.lastname: Ulker
authors.forename: Islim
authors.initials: I
authors.lastname: Volkan
authors.forename: Mehmet
authors.initials: M
authors.lastname: Karaca
authors.forename: Mustafa
authors.initials: M
authors.lastname: Ersoz
authors.forename: Abdulaziz
authors.initials: A
authors.lastname: Gul
authors.forename: Esat
authors.initials: E
authors.lastname: Adiguzel
keywords: Horn Kolb syndrome; acheiria; acheiropodia; transverse limb defect