title: Genome biology: the sleek and oh-so chic Oxytricha nanochromosomes.
abstract: The somatic nucleus of Oxytricha trifallax contains over 15,000 different chromosomes, most containing a single gene. Analysis of this 50 Mb genome uncovers novel regulatory strategies and adaptive potential when gene copy number and allelic frequency are no longer constrained by genetic linkage.
authors.affiliation: Biology Department, Washington University in St. Louis, One Brookings Drive, St. Louis, MO 63130, USA.
authors.forename: Scott A
authors.initials: SA
authors.lastname: Horrell
authors.forename: Douglas L
authors.initials: DL
authors.lastname: Chalker
mesh_terms: D002875:Chromosomes / Q000235:genetics*; D018628:Gene Dosage / Q000235:genetics; D005787:Gene Frequency; D017125:Genes, Protozoan / Q000235:genetics*; D018503:Genome, Protozoan / Q000235:genetics*; D023281:Genomics / Q000379:methods; D048648:Macronucleus / Q000235:genetics*; D016813:Oxytricha / Q000235:genetics*