title: Incorporation of 6-thioguanine nucleotides into DNA during maintenance therapy of childhood acute lymphoblastic leukemia-the influence of thiopurine methyltransferase genotypes.
authors.affiliation: Department of Pediatrics and Adolescent Medicine, The University Hospital Rigshospitalet, Copenhagen, Denmark.
authors.forename: Maria S
authors.initials: MS
authors.lastname: Ebbesen
authors.forename: Jacob
authors.initials: J
authors.lastname: Nersting
authors.forename: Jack H
authors.initials: JH
authors.lastname: Jacobsen
authors.forename: Thomas L
authors.initials: TL
authors.lastname: Frandsen
authors.forename: Kim
authors.initials: K
authors.lastname: Vettenranta
authors.forename: Jonas
authors.initials: J
authors.lastname: Abramsson
authors.forename: Finn
authors.initials: F
authors.lastname: Wesenberg
authors.forename: Kjeld
authors.initials: K
authors.lastname: Schmiegelow
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000493:pharmacokinetics / Q000627:therapeutic use*; D002648:Child; D004247:DNA / Q000378:metabolism*; D005260:Female; D005838:Genotype; D006150:Guanine Nucleotides / Q000378:metabolism; D006801:Humans; D008297:Male; D015122:Mercaptopurine / Q000008:administration & dosage; D008727:Methotrexate / Q000008:administration & dosage; D008780:Methyltransferases / Q000235:genetics*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy* / Q000235:genetics; D013873:Thionucleotides / Q000378:metabolism
chemical_list: D006150:Guanine Nucleotides; D013873:Thionucleotides; C003964:6-thioguanylic acid; D004247:DNA; D015122:Mercaptopurine; D008780:Methyltransferases; C022745:thiopurine methyltransferase; D008727:Methotrexate