title: Visible light photoredox-catalyzed multicomponent reactions.
abstract: Oxidative three-component reactions for the direct synthesis of α-amino amides and imides from tertiary amines have been developed. These reactions involve the functionalization of C(sp(3))-H bonds adjacent to nitrogen atoms via mild aerobic oxidation using visible light photoredox catalysis. The protocols are applicable to a wide range of amines and isocyanides, as well as water and carboxylic acids, providing straightforward access to a variety of highly functionalized α-amino amides and imides.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074 Aachen, Germany. magnus.rueping@rwth-aachen.de
authors.forename: Magnus
authors.initials: M
authors.lastname: Rueping
authors.forename: Carlos
authors.initials: C
authors.lastname: Vila