title: Synthesis of 1,4,5-trisubstituted 1,2,3-triazoles amicable for automation.
abstract: A three-component 3+2 cycloaddition reaction followed by Suzuki coupling reaction was carried out to synthesize a library of compounds using automation (parallel synthesizer). Scaffolds that are unexplored in literature were used for the synthesis of library. The iodo-triazoles formed by 3+2 cycloaddition reaction were coupled with boronic acids to get tri-substituted triazoles.
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology, Hyderabad 500 007, A.P., India.
authors.forename: Mitta
authors.initials: M
authors.lastname: Kavitha
authors.forename: Bodugam
authors.initials: B
authors.lastname: Mahipal
authors.forename: Prathama S
authors.initials: PS
authors.lastname: Mainkar
authors.forename: Srivari
authors.initials: S
authors.lastname: Chandrasekhar
mesh_terms: D001897:Boronic Acids / Q000737:chemistry; D061565:Cycloaddition Reaction; D054879:Halogenation; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001897:Boronic Acids; D014230:Triazoles