title: Protamine-induced thrombocytopenia?
abstract: In this issue of Blood, Bakchoul et al and Lee et al describe and characterize a common but only recently recognized immune response to protamine after cardiopulmonary bypass (CPB) surgery with potential important clinical implications.
authors.affiliation: Perelman School of Medicine, University of Pennsylvania.
authors.forename: Adam
authors.initials: A
authors.lastname: Cuker
authors.forename: Douglas B
authors.initials: DB
authors.lastname: Cines
mesh_terms: D000818:Animals; D000906:Antibodies / Q000097:blood*; D002315:Cardiopulmonary Bypass; D005260:Female; D006493:Heparin / Q000276:immunology*; D006801:Humans; D008297:Male; D011479:Protamines / Q000276:immunology*; D013921:Thrombocytopenia / Q000276:immunology*
chemical_list: D000906:Antibodies; D011479:Protamines; D006493:Heparin