title: Frequency of non-motor symptoms in Peruvian patients with Parkinson's disease.
abstract: BACKGROUND
  Non-motor symptoms in Parkinson's disease are often not well recognized in clinical practice. Non-motor symptoms questionnaire (NMSQuest) is a simple instrument that allows patients or caregivers to report non-motor symptoms in a practical manner.
  
  
  OBJECTIVE
  We attempted to determine the prevalence of non-motor symptoms in three hundred Parkinson's disease outpatients.
  
  
  RESULTS
  The mean total non-motor symptoms was 12.41, ranging from 0 to 27 of a maximum of 30. At least one was present in 99.3% of patients. A progressive increase in mean total score was observed across each 5-year interval. Depression domain scored the most "positive" answers while urinary and anxiety /memory were secondly and thirdly most prevalent respectively.
  
  
  CONCLUSIONS
  The large number of patients included in this study allowed evaluation of the occurrence of non-motor symptoms in early and advanced disease in addition to the relationship of these kinds of symptoms with progression of disease.
authors.affiliation: Movement Disorders Unit, Instituto Nacional de Ciencias Neurologicas, Lima 1, Peru. cosentinoe@gmail.com
authors.forename: Carlos
authors.initials: C
authors.lastname: Cosentino
authors.forename: Yesenia
authors.initials: Y
authors.lastname: Nuñez
authors.forename: Luis
authors.initials: L
authors.lastname: Torres
mesh_terms: D000328:Adult; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology; D015995:Prevalence; D012720:Severity of Illness Index; D063189:Symptom Assessment / Q000706:statistics & numerical data*