title: [Significance of genetic tests in the era of personalized medicine].
abstract: Due to the rapid development in genomics, genetic markers gain importance in all areas of medicine including prevention, management and therapy of patients. As a result, medicine started to shift away from evidence based procedures to a more personalized one. However, the later one requires high quality validated genetic tests. These new tests appeared as preconceptional, preimplantational, prenatal, presymptomatic, diagnostic and direct to consumer forms. Before approval such tests must be analytically and clinically validated. Broader use of these genetic tests is dependent on their price and reimbursement schemes.
authors.affiliation: Genomikai Medicina és Ritka Betegségek Intézete, Semmelweis Egyetem, Budapest, Hungary. molnarmj@gmail.com
authors.forename: Judit Mária
authors.initials: JM
authors.lastname: Molnár
authors.forename: Szilvia
authors.initials: S
authors.lastname: Magyarósi
authors.forename: György
authors.initials: G
authors.lastname: Németh
mesh_terms: D014408:Biomarkers, Tumor; D019317:Evidence-Based Medicine; D005819:Genetic Markers; D005820:Genetic Testing / Q000379:methods / Q000639:trends*; D023281:Genomics / Q000191:economics / Q000639:trends; D006801:Humans; D008389:Marketing of Health Services / Q000639:trends; D010597:Pharmacogenetics; D057285:Precision Medicine / Q000379:methods* / Q000639:trends*; D016742:Preconception Care; D019836:Preimplantation Diagnosis; D011296:Prenatal Diagnosis
chemical_list: D014408:Biomarkers, Tumor; D005819:Genetic Markers