title: Effects of postoperative weight-bearing on body composition and bone mineral density after uncemented total hip arthroplasty.
abstract: OBJECTIVE
  To investigate whether a postoperative weight-bearing regimen affects changes in bone mineral density and body composition after uncemented total hip arthroplasty, and to investigate the changes over a 5-year period after the surgical procedure.
  
  
  METHODS
  Secondary analysis of a previous randomized controlled trial.
  
  
  METHODS
  A total of 39 patients were randomized to immediate full weight-bearing or partial weight-bearing for 3 months. Dual-energy X-ray absorptiometry was used to measure bone mineral density of the contralateral hip and both heels and to measure body composition.
  
  
  RESULTS
  The weight-bearing regimen had no effect on change in bone mineral density or body composition after 3 and 12 months. At 5 years, there was a decrease in bone mineral density of 3% in the total body and 2-3% in the contralateral hip regions. At 5 years we found a decrease in total body bone mineral content of 5%, but no changes in fat mass or lean mass compared with preoperative values.
  
  
  CONCLUSIONS
  The postoperative weight-bearing regimen had no effect on changes in body composition or bone mineral density. Five years after total hip arthroplasty there was a decrease in bone mineral content and bone mineral density, but no changes in lean mass or fat mass.
authors.affiliation: Dept of Orthopedics, Uppsala University Hospital, Uppsala, Sweden. olof.wolf@akademiska.se
authors.forename: Olof
authors.initials: O
authors.lastname: Wolf
authors.forename: Per
authors.initials: P
authors.lastname: Mattsson
authors.forename: Jan
authors.initials: J
authors.lastname: Milbrink
authors.forename: Sune
authors.initials: S
authors.lastname: Larsson
authors.forename: Hans
authors.initials: H
authors.lastname: Mallmin
mesh_terms: D000328:Adult; D019644:Arthroplasty, Replacement, Hip / Q000534:rehabilitation*; D001823:Body Composition; D001843:Bone Cements; D015519:Bone Density; D005260:Female; D006621:Hip Joint / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000601:surgery*; D011182:Postoperative Care; D016474:Weight-Bearing / Q000502:physiology*
chemical_list: D001843:Bone Cements