title: Effect of Solanum surattense seed on the oxidative potential of cauda epididymal spermatozoa.
abstract: OBJECTIVE
  To evaluate the effect of aqueous seed extract of Solanum surattense (S. surattense) on the oxidative potential of cauda epididymal spermatozoa.
  
  
  METHODS
  S. surattense seed extract was orally administered at the dosage of 10 mg/kg b.w. for 15 days, after which aspartate transferase (AST), alanine transferase (ALT), glutamate dehydrogenase (GDH), citric acid and iso-citrate dehydrogenase (ICDH) were assayed.
  
  
  RESULTS
  The activity levels of the enzymes AST and ALT, which are considered to be the androgenicity in the sperm suspension, were depleted in the extract fed rats. The activity level of the enzyme ICDH, was reduced significantly in the treated group (P<0.001).
  
  
  CONCLUSIONS
  It can be concluded that the oral administration of the aqueous seed extract of S. surattense can deplete the oxidative stress of cauda epididymal spermatozoa in albino rats.
authors.affiliation: Post Graduate and Research Department of Zoology, Voorhees College, Physiology Wing, Vellore-632 001, Tamilnadu, India.
authors.forename: T
authors.initials: T
authors.lastname: Thirumalai
authors.forename: E
authors.initials: E
authors.lastname: David
authors.forename: Therasa S
authors.initials: TS
authors.lastname: Viviyan
authors.forename: E K
authors.initials: EK
authors.lastname: Elumalai
mesh_terms: D000410:Alanine Transaminase / Q000032:analysis; D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification / Q000494:pharmacology*; D001219:Aspartate Aminotransferases / Q000032:analysis; D005969:Glutamate Dehydrogenase / Q000032:analysis; D007521:Isocitrate Dehydrogenase / Q000032:analysis; D008297:Male; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D017208:Rats, Wistar; D012639:Seeds / Q000737:chemistry*; D032322:Solanum / Q000737:chemistry*; D013094:Spermatozoa / Q000187:drug effects* / Q000201:enzymology
chemical_list: D000975:Antioxidants; D010936:Plant Extracts; D007521:Isocitrate Dehydrogenase; D005969:Glutamate Dehydrogenase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
keywords: Antifertility; Contraception; Solanum surattense; Sperm