title: Spectral-domain optical coherence tomography study of macular structure as prognostic and determining factor for macular hole surgery outcome.
abstract: OBJECTIVE
  To evaluate postoperative spectral-domain optical coherence tomography findings after macular hole surgery.
  
  
  METHODS
  Retrospective, interventional, nonrandomized study. Overall, 164 eyes of 157 patients diagnosed with macular hole were operated on by vitrectomy and internal limiting membrane peeling. Preoperative and postoperative best-corrected visual acuity and spectral-domain optical coherence tomography images were obtained. Two groups were considered on the basis of the postoperative integrity of the back reflection line from the ellipsoid portion of the photoreceptor inner segment: group A (disruption of ellipsoid portion of the inner segment line, 60 eyes) and group B (restoration of ellipsoid portion of the inner segment line, 104 eyes).
  
  
  RESULTS
  Logarithm of the minimum angle of resolution best-corrected visual acuity improved significantly after the surgery of macular hole from a mean preoperative value of 0.79 ± 0.37 (range, 0.15-2.00) to a mean postoperative value of 0.35 ± 0.31 (range, 0.00-1.30) at the last follow-up visit (P < 0.01). Best-corrected visual acuity improved significantly in the 2 groups analyzed (all P < 0.01). A larger improvement was found in group B than in group A (P < 0.01).
  
  
  CONCLUSIONS
  Ellipsoid portion of the inner segment line reconstruction seems to be a good prognostic factor for visual rehabilitation after macular hole surgery.
authors.affiliation: Department of Ophthalmology, Castilla La Mancha University, Albacete, Spain. josemaria.ruiz@uclm.es
authors.forename: José M
authors.initials: JM
authors.lastname: Ruiz-Moreno
authors.forename: Luis
authors.initials: L
authors.lastname: Arias
authors.forename: Javier
authors.initials: J
authors.lastname: Araiz
authors.forename: José
authors.initials: J
authors.lastname: García-Arumí
authors.forename: Javier A
authors.initials: JA
authors.lastname: Montero
authors.forename: David P
authors.initials: DP
authors.lastname: Piñero
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019773:Epiretinal Membrane / Q000601:surgery; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D012167:Retinal Perforations / Q000175:diagnosis / Q000601:surgery*; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods*