title: Accuracy of trabecular bone microstructural measurement at planned dental implant sites using cone-beam CT datasets.
abstract: OBJECTIVE
  Cone-beam CT (CBCT) images are infrequently utilized for trabecular bone microstructural measurement due to the system's limited resolution. The aim of this study was to determine the accuracy of CBCT for measuring trabecular bone microstructure in comparison with micro CT (μCT).
  
  
  METHODS
  Twenty-four human mandibular cadavers were scanned using a CBCT system (80 μm) and a μCT system (35 μm). Three bone microstructural parameters trabecular number (Tb.N), thickness (Tb.Th) and separation (Tb.Sp) were assessed using CTAn imaging software.
  
  
  RESULTS
  Intraclass correlation coefficients (ICC) showed a high intra-observer reliability (≥ 0.996) in all parameters for both systems. The Pearson correlation coefficients between the measurements of the two systems were for Tb.Th 0.82, for Tb.Sp 0.94 and for Tb.N 0.85 (all P's<0.001). The Bland and Altman plots showed strongest agreement in Tb.N (-0.37 μm) followed by Tb.Th (1.6 μm) and Tb.Sp (8.8 μm).
  
  
  CONCLUSIONS
  Cone-beam CT datasets can be used to evaluate trabecular bone microstructure at dental implant sites. The accuracy for measuring Tb.N was the best followed by Tb.Th and Tb.Sp.
authors.affiliation: Department of General and Specialized Dentistry, Section of Oral and Maxillofacial Radiology, Academic Center for Dentistry Amsterdam (ACTA), Amsterdam, The Netherlands; Department of General Dental Practice and Oral & Maxillofacial Imaging, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: Norliza
authors.initials: N
authors.lastname: Ibrahim
authors.forename: Azin
authors.initials: A
authors.lastname: Parsa
authors.forename: Bassam
authors.initials: B
authors.lastname: Hassan
authors.forename: Paul
authors.initials: P
authors.lastname: van der Stelt
authors.forename: Irene H A
authors.initials: IH
authors.lastname: Aartman
authors.forename: Daniel
authors.initials: D
authors.lastname: Wismeijer
mesh_terms: D015519:Bone Density; D002102:Cadaver; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D015921:Dental Implants; D006801:Humans; D008334:Mandible / Q000000981:diagnostic imaging*; D011857:Radiographic Image Interpretation, Computer-Assisted
chemical_list: D015921:Dental Implants
keywords: cone-beam computed tomography; dental implants; micro-computed tomography; microarchitecture; trabecular bone