title: Orbital malignant melanoma associated with nevus of Ota.
abstract: Nevus of Ota (oculodermal melanosis) is a dermal melanocytic hamartoma with bluish hyperpigmentation along the first and second branches of the trigeminal nerve. Extracutaneous involvement, especially ocular, has been reported. A 45-year-old male presented with malignant melanoma of the left orbit in association with nevus of Ota. Being locally invasive, a modified exenteration with frontal flap repair was done on left eye. Adjuvant chemotherapy was given after wound healing. All pigmented lesions of the eye require close monitoring to help in the early diagnosis. Since malignant transformation has been reported in oculodermal melanosis, close follow-up and patient education will facilitate early diagnosis and prompt management. This case is reported for its rarity and unusual presentation.
authors.affiliation: Department of Ophthalmology, Amala Institute of Medical Sciences, Thrissur, Kerala, India.
authors.forename: Cherungottil V
authors.initials: CV
authors.lastname: Radhadevi
authors.forename: Kakkuzhiyil S
authors.initials: KS
authors.lastname: Charles
authors.forename: Vasu K
authors.initials: VK
authors.lastname: Lathika
mesh_terms: D002471:Cell Transformation, Neoplastic; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000601:surgery; D009507:Nevus of Ota / Q000473:pathology* / Q000601:surgery; D009918:Orbital Neoplasms / Q000473:pathology* / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery