title: [Cutaneous carcinoma induced by radiotherapy: a report of 31 cases].
abstract: BACKGROUND
  Depilatory radiotherapy was used in the sixties as a treatment for ringworm in Tunisia. Subsequently some of these patients developed radio-induced carcinomas of the scalp.
  
  
  OBJECTIVE
  To present the epidemiological, clinical, pathological,therapeutic features and out come of radio-induced cutaneous carcinomas.
  
  
  METHODS
  We conducted a retrospective study performed in the dermatology department of the La Rabta hospital of Tunis over a 6- year-period recording all histologically confirmed carcinomas in patients irradiated in childhood for tinea capitis.
  
  
  RESULTS
  Thirty one patients were included with 49 tumors: 47 basal cell carcinomas and 2 squamous cell carcinomas. The average latent period between the irradiation and the appearance of the carcinomas was of 35.7 years. The average age was 53 years. A male predominance was noted, with a sex ratioM/F of 6.75. Clinically, basal cell carcinomas were nodular in all cases. Surgery was indicated in 90% of cases. Cryosurgery and radiotherapy were used respectively in 1 and 2 patients.
  
  
  CONCLUSIONS
  Our study shows that radio-induced cutaneous carcinomas are widely dominated by basal cell carcinoma. They arise, approximately, ten years earlier than carcinoma in patients with no history of scalp irradiation. However X-ray exposure does not seem to influence clinical or histological presentation, therapeutic modalities nor prognosis of these tumors. The prognosis of radioinduced cutaneous carcinomas was globally similar to that of other cutaneous carcinomas with same histological type and equivalent degree of invasion.
authors.forename: Inès
authors.initials: I
authors.lastname: Zaraa
authors.forename: Sabra
authors.initials: S
authors.lastname: Ben Taazayet
authors.forename: Héla
authors.initials: H
authors.lastname: Zribi
authors.forename: Inès
authors.initials: I
authors.lastname: Chelly
authors.forename: Dalenda
authors.initials: D
authors.lastname: El Euch
authors.forename: Sondes
authors.initials: S
authors.lastname: Trojjet
authors.forename: Mourad
authors.initials: M
authors.lastname: Mokni
authors.forename: Slim
authors.initials: S
authors.lastname: Haouet
authors.forename: Amel
authors.initials: A
authors.lastname: Ben Osman
mesh_terms: D000328:Adult; D000368:Aged; D002280:Basal Cell Carcinoma / Q000209:etiology*; D002294:Carcinoma, Squamous Cell / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced; D012189:Retrospective Studies; D012535:Scalp; D012878:Skin Neoplasms / Q000209:etiology*; D014006:Tinea Capitis / Q000532:radiotherapy