title: Breast cancer incidence rates among orthodox Jewish women.
abstract: BRCA 1/BRCA2 founder mutations have been documented among Ashkenazi Jews. Little is known about cancer rates and cancer-related health behaviors among an insular subset of this population, Orthodox Jews. The goal of this study was estimate the risk of breast and ovarian among the Orthodox Jewish population. We used geo-coding with surveillance, epidemiology, and end results (SEER) data to identify this subgroup and estimate breast and ovarian cancer rates. Relative to neighborhoods with lower estimated Jewish populations, higher breast cancer rates were found in neighborhoods with higher estimated Orthodox Jewish population, there were no comparable differences in ovarian cancer rates. Implications include more research on health behaviors that may contribute to breast cancer in this insular community.
authors.affiliation: Department of Oncology, Wayne State University/Karmanos Cancer Institute, 4100 John R MM03BF, Detroit, MI, 48201, USA, tkatchr@karmanos.org.
authors.forename: Rifky
authors.initials: R
authors.lastname: Tkatch
authors.forename: Kendra
authors.initials: K
authors.lastname: Schwartz
authors.forename: Ronald D
authors.initials: RD
authors.lastname: Shore
authors.forename: Louis A
authors.initials: LA
authors.lastname: Penner
authors.forename: Michael S
authors.initials: MS
authors.lastname: Simon
authors.forename: Terrance L
authors.initials: TL
authors.lastname: Albrecht
mesh_terms: D001943:Breast Neoplasms / Q000453:epidemiology* / Q000208:ethnology; D005260:Female; D006801:Humans; D015994:Incidence; D007585:Jews / Q000208:ethnology / Q000706:statistics & numerical data*; D008824:Michigan / Q000453:epidemiology; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000208:ethnology; D018426:SEER Program