title: [Pregnancy in Gaucher disease].
abstract: Gaucher disease is a lysosomal storage disorder due to deficiency of glucocerebrosidase. The association with pregnancy exposes the worsening of the disease and complications of pregnancy and puerperium. We report a case of pregnancy in a woman of 35 years, suffering from Gaucher disease type 1. Pregnancy had a favorable outcome. Complications occurred. They were kept under control. The outcome was favorable. The authors discuss the evolution of the disease during pregnancy and management of complications. They can occur during pregnancy, post-partum and breastfeeding. Support begins with preconception consultation. It involves finding and correcting the biological problems and deficiencies, and management of complications. Genetic counseling is important, it helps prevent inbreeding.
authors.affiliation: Service de gynécologie-obstétrique, faculté de médecine et de pharmacie, université Ain Chok, centre hospitalier universitaire Ibn Rochd, Casablanca, Maroc. Electronic address: mohcineb@yahoo.fr.
authors.forename: H
authors.initials: H
authors.lastname: Boufettal
authors.affiliation: Service d'hématologie et d'oncologie pédiatrique, faculté de médecine et de pharmacie, université Ain Chok, hôpital du 20-Août, centre hospitalier universitaire Ibn Rochd, Casablanca, Maroc.
authors.forename: A
authors.initials: A
authors.lastname: Quessar
authors.affiliation: Service de gynécologie-obstétrique, faculté de médecine et de pharmacie, université Ain Chok, centre hospitalier universitaire Ibn Rochd, Casablanca, Maroc.
authors.forename: Z
authors.initials: Z
authors.lastname: Jeddaoui
authors.affiliation: Service de gynécologie-obstétrique, faculté de médecine et de pharmacie, université Ain Chok, centre hospitalier universitaire Ibn Rochd, Casablanca, Maroc.
authors.forename: S
authors.initials: S
authors.lastname: Mahdoui
authors.affiliation: Service de gynécologie-obstétrique, faculté de médecine et de pharmacie, université Ain Chok, centre hospitalier universitaire Ibn Rochd, Casablanca, Maroc.
authors.forename: M
authors.initials: M
authors.lastname: Noun
authors.affiliation: Service de gynécologie-obstétrique, faculté de médecine et de pharmacie, université Ain Chok, centre hospitalier universitaire Ibn Rochd, Casablanca, Maroc.
authors.forename: S
authors.initials: S
authors.lastname: Hermas
authors.affiliation: Service de gynécologie-obstétrique, faculté de médecine et de pharmacie, université Ain Chok, centre hospitalier universitaire Ibn Rochd, Casablanca, Maroc.
authors.forename: N
authors.initials: N
authors.lastname: Samouh
mesh_terms: D002585:Cesarean Section; D005260:Female; D005776:Gaucher Disease / Q000150:complications / Q000628:therapy*; D006529:Hepatomegaly / Q000209:etiology / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D006473:Postpartum Hemorrhage / Q000209:etiology / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011263:Pregnancy Trimester, Third
keywords: Allaitement; Breastfeeding; Conseil génétique; Counseling; Gaucher disease; Grossesse; Hémorragie du post-partum; Maladie de Gaucher; Misoprostol; Post-partum hemorrhage; Pregnancy