title: Oncocytic Schneiderian papillomas: Clinical behavior and outcomes of the endoscopic endonasal approach in 33 cases.
abstract: BACKGROUND
  The purpose of this study was to evaluate the clinical behavior of oncocytic Schneiderian papillomas in relation to the rate of malignant transformation and recurrences and to report the long-term results of the endoscopic endonasal treatment.
  
  
  METHODS
  A retrospective analysis was carried out on patients with oncocytic papilloma, endoscopically managed over the past 20 years, at 2 university centers following a uniform policy.
  
  
  RESULTS
  Thirty-three patients were treated between November 1991 and December 2010. The mean follow-up period was 62 months. We observed 2 cases of persistence (6%) at the maxillary sinus level. Both of these patients underwent endoscopic surgical revision. Squamous cell carcinoma (SCC) was observed in 1 patient (3%).
  
  
  CONCLUSIONS
  The endonasal endoscopic technique proved to be a safe and effective approach for the treatment of oncocytic papillomas. An oncocytic papilloma is not to be considered a negative prognostic factor in terms of malignant transformation or recurrence.
authors.affiliation: Department of Otorhinolaryngology, University of Sassari, Sassari, Italy.
authors.forename: Apostolos
authors.initials: A
authors.lastname: Karligkiotis
authors.forename: Maurizio
authors.initials: M
authors.lastname: Bignami
authors.forename: Paola
authors.initials: P
authors.lastname: Terranova
authors.forename: Stefania
authors.initials: S
authors.lastname: Gallo
authors.forename: Francesco
authors.initials: F
authors.lastname: Meloni
authors.forename: Giovanni
authors.initials: G
authors.lastname: Padoan
authors.forename: Davide
authors.initials: D
authors.lastname: Lombardi
authors.forename: Piero
authors.initials: P
authors.lastname: Nicolai
authors.forename: Paolo
authors.initials: P
authors.lastname: Castelnuovo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D002471:Cell Transformation, Neoplastic; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007558:Italy; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000601:surgery; D009297:Nasal Mucosa / Q000473:pathology; D009361:Neoplasm Invasiveness / Q000473:pathology; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D009367:Neoplasm Staging; D009669:Nose Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D024862:Oxyphil Cells / Q000473:pathology; D018308:Papilloma, Inverted / Q000473:pathology* / Q000601:surgery*; D010255:Paranasal Sinus Neoplasms / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies; D018570:Risk Assessment; D012494:Sampling Studies; D015996:Survival Rate; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: endoscopic endonasal approach; inverted papilloma; oncocytic Schneiderian papilloma; sinonasal benign tumors; skull base