title: A mechanistic approach to preventing schizophrenia in at-risk individuals.
abstract: In this issue of Neuron, Schobel et al. (2013) report that excess hippocampal glutamate may cause transition to psychosis in individuals at high risk for schizophrenia. Their data has implications for prevention strategies and why stress often precipitates this transition.
authors.affiliation: Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA. bita@pitt.edu
authors.forename: Bita
authors.initials: B
authors.lastname: Moghaddam