title: Anatomical MRI with an atomic magnetometer.
abstract: Ultra-low field (ULF) MRI is a promising method for inexpensive medical imaging with various additional advantages over conventional instruments such as low weight, low power, portability, absence of artifacts from metals, and high contrast. Anatomical ULF MRI has been successfully implemented with SQUIDs, but SQUIDs have the drawback of a cryogen requirement. Atomic magnetometers have sensitivity comparable to SQUIDs and can be in principle used for ULF MRI to replace SQUIDs. Unfortunately some problems exist due to the sensitivity of atomic magnetometers to a magnetic field and gradients. At low frequency, noise is also substantial and a shielded room is needed for improving sensitivity. In this paper, we show that at 85 kHz, the atomic magnetometer can be used to obtain anatomical images. This is the first demonstration of any use of atomic magnetometers for anatomical MRI. The demonstrated resolution is 1.1 mm×1.4 mm in about 6 min of acquisition with SNR of 10. Some applications of the method are discussed. We discuss several measures to increase the sensitivity to reach a resolution 1 mm×1 mm.
authors.affiliation: Los Alamos National Laboratory, Los Alamos, NM 87545, USA. isavukov@lanl.gov
authors.forename: I
authors.initials: I
authors.lastname: Savukov
authors.forename: T
authors.initials: T
authors.lastname: Karaulanov
mesh_terms: D004867:Equipment Design; D019544:Equipment Failure Analysis; D006225:Hand / Q000033:anatomy & histology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D008280:Magnetics / Q000295:instrumentation*; D060306:Magnetometry / Q000295:instrumentation*; D008904:Miniaturization; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014159:Transducers