title: Purulent bullous epidermal necrolysis: A potential new clinical pattern of drug eruption.
abstract: Drug eruption is a major problem of adverse drug reactions and may present as variform clinical manifestations. Toxic epidermal necrolysis (TEN) and acute generalized exanthematous pustulosis (AGEP) are relatively rare severe drug eruptions. It has rarely been reported that AGEP overlaps or mimics TEN, while no purulent bullous epidermal necrolysis has been reported. The present study reports a rare case of an adult female patient with the clinical manifestations of purulent bulla and epidermal necrolysis caused by drug ingestion. The case is discussed to reveal whether a new clinical pattern of drug eruption has been identified.
authors.affiliation: Department of Dermatology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, P.R. China.
authors.forename: Lun-Fei
authors.initials: LF
authors.lastname: Liu
authors.forename: Jian-Liang
authors.initials: JL
authors.lastname: Yan
authors.forename: Jian-You
authors.initials: JY
authors.lastname: Wang
authors.forename: Ji-Su
authors.initials: JS
authors.lastname: Chen
authors.forename: Sui-Qing
authors.initials: SQ
authors.lastname: Cai
authors.forename: Li-Min
authors.initials: LM
authors.lastname: Lao
authors.forename: Min
authors.initials: M
authors.lastname: Zheng
keywords: drug eruption; epidermal necrolysis; purulent bulla