title: A case report of herpetic and candidal esophagitis in an immunocompetent adult.
abstract: Reports of combined candidal and herpetic esophagitis in immunocompetent states are rare and sporadic. A 44-year-old previously healthy lady presented with a one week history of progressive dysphagia, odynophagia and fever. Esophagogastroduodenoscopy (EGD) showed extensive desquamation of the entire esophagus except for distal 4 cm. Histopathological examination revealed ulcerated and inflamed squamous epithelium with the margin of ulcer showing a few overhanging squamous cells with dense eosinophilic cytoplasm, multinucleated and faceted nuclei with glassy chromatin, and an occasional Cowdry type A intranuclear inclusion bodies. Few candidal spores were seen in the underlying stroma. Intravenous acyclovir, fluconazole and pantoprazole were initiated. Oral analgesics were given for pain relief. She was treated for a total of 14 days. She showed significant improvement and was tolerating oral intake after discharge. The patient was asymptomatic with no evidence of recurrence at a 2-month follow-up.
authors.affiliation: Department of Internal Medicine, Kasturba Medical College, Manipal, Manipal University, Karnataka, India.
authors.forename: Vishwanath
authors.initials: V
authors.lastname: Sathyanarayanan
authors.forename: Abdul
authors.initials: A
authors.lastname: Razak
authors.forename: M Mukhyprana
authors.initials: MM
authors.lastname: Prabhu
authors.forename: Kavitha
authors.initials: K
authors.lastname: Saravu
authors.forename: Pai C
authors.initials: PC
authors.lastname: Ganesh
authors.forename: Anuradha K
authors.initials: AK
authors.lastname: Rao
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D004941:Esophagitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000821:virology*; D004947:Esophagus / Q000382:microbiology / Q000473:pathology / Q000821:virology; D005260:Female; D006561:Herpes Simplex / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D006801:Humans; D007181:Inclusion Bodies, Viral; D013172:Spores, Fungal; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D000998:Antiviral Agents