title: A rare occurrence and management of familial schwannomatosis.
abstract: We are presenting a familial schwannomatosis without the features of neurofibromatosis (NF). We retrospectively reviewed the hospital charts, radiology films, operative notes and pathology slides of the patient. There was a family history of schwannomatosis. The patient had contrast-enhanced MRI, which was negative for vestibular schwannomas. The patient underwent surgical excision of symptomatic lesions. Histopathology confirmed these lesions as schwannomas consisting of areas of Antoni A and B, and immunohistochemical study was positive for S-100 protein. We recommend surgery for symptomatic lesions. Asymptomatic tumours can be monitored. Regular follow-up is essential as they may develop fresh lesions at any time. The relevant literature is discussed.
authors.affiliation: Department of General Surgery, Vydehi Institute of Medical Sciences, Bangalore, Karnataka, India.
authors.forename: Ramesh G
authors.initials: RG
authors.lastname: Reddy
authors.forename: Vanaja Reddy
authors.initials: VR
authors.lastname: Banda
authors.forename: Shankar
authors.initials: S
authors.lastname: Gunadal
authors.forename: Naveen Reddy
authors.initials: NR
authors.lastname: Banda
mesh_terms: D000328:Adult; D001706:Biopsy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009442:Neurilemmoma / Q000235:genetics / Q000473:pathology* / Q000601:surgery*; D017253:Neurofibromatoses / Q000235:genetics / Q000473:pathology* / Q000601:surgery*; D012878:Skin Neoplasms / Q000235:genetics / Q000473:pathology* / Q000601:surgery*; D055815:Young Adult