title: Rapid relief of intertrigo-associated pruritus due to Candida albicans with isoconazole nitrate and diflucortolone valerate combination therapy.
abstract: A 43-year-old male, with intertrigo due to Candida albicans located at the inguinal folds and accompanied by severe pruritus, was treated with topical 1% isoconazole nitrate and 0.1% diflucortolone valerate (2 applications/day for 7 days). An improvement of pruritus was reported 2 days after the beginning of the treatment. Skin lesions improved after 3 days of treatment. Complete remission of both skin lesions and pruritus was observed at day 7. No side effects were observed.
authors.affiliation: Department of Pathophysiology and Transplantation, University of Milan, IRCCS Foundation, Cà Granda Ospedale Maggiore Policlinico, Milan, Italy. stefano.veraldi@unimi.it
authors.forename: Stefano
authors.initials: S
authors.lastname: Veraldi
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D000935:Antifungal Agents / Q000008:administration & dosage*; D002176:Candida albicans / Q000302:isolation & purification*; D002177:Candidiasis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D004060:Diflucortolone / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004338:Drug Combinations; D006801:Humans; D007402:Intertrigo / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D008825:Miconazole / Q000008:administration & dosage / Q000031:analogs & derivatives*; D011537:Pruritus / Q000188:drug therapy / Q000209:etiology*; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D004338:Drug Combinations; C020531:Travocort; D008825:Miconazole; D004060:Diflucortolone