title: Investigating intermediary variables in the physical activity and quality of life relationship in persons with spinal cord injury.
abstract: OBJECTIVE
  Leisure time physical activity (LTPA) has been consistently associated with quality of life (QOL) in people with spinal cord injury (SCI). However, recent research suggests that intermediary variables account for the LTPA-QOL relationship in other populations. Using a prospective design, this study examined potential intermediary constructs linking LTPA and QOL in people with SCI. Drawing from previous literature, a longitudinal structural equation model was developed and tested to determine if depression, functional independence, social integration/participation, and self-efficacy mediate the LTPA-QOL relationship.
  
  
  METHODS
  Participants (n = 395) were adults with SCI who reported engaging in at least some LTPA over an 18-month period. LTPA was assessed at baseline, the intermediary variables of depression, functional independence, social integration/participation and self-efficacy were measured at 6-months, and QOL was evaluated at 18-months.
  
  
  RESULTS
  The structural model had minimally acceptable fit [χ²(395) = 803.16, p > .05; CFI = .90, RMSEA = .05 and SRMR = .06]. Baseline LTPA was related to functional independence (β = .20, p > .05), depression (β = -.32, p > .05) and self-efficacy (β = .60, p > .05) at 6 months. Six-month functional independence (β = .15, p > .05), social participation (β = .21, p > .05) and depression (β = -.34, p > .05) significantly predicted 18-month QOL. Only functional independence and depression were significant mediators.
  
  
  CONCLUSIONS
  These results suggest that LTPA may improve QOL in adults with SCI through its influence on functional independence and depression.
authors.affiliation: School of Kinesiology and Health Studies, Queen’s University, Kingston, Ontario, Canada. shane.sweet@queensu.ca
authors.forename: Shane N
authors.initials: SN
authors.lastname: Sweet
authors.forename: Kathleen A
authors.initials: KA
authors.lastname: Martin Ginis
authors.forename: Jennifer R
authors.initials: JR
authors.lastname: Tomasone
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D003863:Depression; D005260:Female; D006801:Humans; D007899:Leisure Activities / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology; D020377:Self Efficacy; D057566:Self Report; D058992:Social Participation; D013119:Spinal Cord Injuries / Q000523:psychology*