title: Hit parade for adoptive cell transfer therapy: the best T cells for superior clinical responses.
abstract: Adoptive cell transfer (ACT) of T cells has great clinical potential, but the numerous variables of this therapy make choices difficult. A new study takes advantage of a novel technology for characterizing the T-cell responses of patients. If applied systematically, this approach may identify biomedical correlates of protection, thereby supporting treatment optimization.
authors.affiliation: Department of Oncology and Ludwig Center for Cancer Research, University of Lausanne, Lausanne, Switzerland. doc@dspeiser.ch
authors.forename: Daniel E
authors.initials: DE
authors.lastname: Speiser
mesh_terms: D005260:Female; D006801:Humans; D016219:Immunotherapy, Adoptive; D058965:MART-1 Antigen / Q000276:immunology*; D008297:Male; D008545:Melanoma / Q000628:therapy*; D012878:Skin Neoplasms / Q000628:therapy*; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D058965:MART-1 Antigen