title: Synthesis of various secosteroidal macrocycles by ring-closing metathesis.
abstract: We set out to describe an efficient and versatile method for preparing secosteroidal macrocycles from cholic acid, via an oxidative ring-expansion/ring-opening sequence and a ring-closing metathesis reaction as the key steps. The characteristic ¹H and ¹³C NMR spectroscopic features of the synthesized compounds are reported.
authors.affiliation: CNRS Institut des Sciences Moléculaires de Marseille UMR 7313, Aix Marseille Université, 13397 Marseille, France. malika.ibrahim@univ-amu.fr
authors.forename: Malika
authors.initials: M
authors.lastname: Ibrahim-Ouali
authors.forename: Eugénie
authors.initials: E
authors.lastname: Romero
mesh_terms: D047028:Macrocyclic Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D047028:Macrocyclic Compounds