title: Tubular woven narrow fabrics for replacement of cruciate ligaments.
abstract: The human knee is one of the most frequently injured joints. More than half of these injuries are related to a failure of the anterior cruciate ligament. Current treatments (allogeneic and autologous) bear several disadvantages which can be overcome through the use of synthetic structures. Within the scope of this paper the potential of tubular woven fabrics for the use as artificial ligaments has been evaluated. Twelve fabrics made of polyethylene terephthalate and polytetrafluoroethylene were produced using shuttle weaving technology. Mechanical and biological properties of the fabrics were assessed using static tensile testing and cytotoxicity assays. The results obtained within this study show that woven tubular fabrics can be potentially used as artificial ligament structures as they can provide the desired medical and mechanical properties for cruciate ligament replacements. Through the choice of material and weaving parameters the fabrics' tensile properties can imitate the stress-strain characteristic of the human cruciate ligament. Further assessments in terms of cyclic loading behavior and abrasion resistance of the material are needed to evaluate the success in long term implantation.
authors.affiliation: Institut für Textiltechnik der RWTH Aachen University, Otto-Blumenthal-Str. 1, 52074, Aachen, Germany. yves.gloy@ita.rwth-aachen.de
authors.forename: Yves-Simon
authors.initials: YS
authors.lastname: Gloy
authors.forename: M
authors.initials: M
authors.lastname: Loehrer
authors.forename: B
authors.initials: B
authors.lastname: Lang
authors.forename: L
authors.initials: L
authors.lastname: Rongen
authors.forename: T
authors.initials: T
authors.lastname: Gries
authors.forename: S
authors.initials: S
authors.lastname: Jockenhoevel
mesh_terms: D005260:Female; D061307:Human Umbilical Vein Endothelial Cells / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D008297:Male; D008422:Materials Testing; D011093:Polyethylene Terephthalates / Q000737:chemistry*; D016119:Posterior Cruciate Ligament; D019736:Prostheses and Implants
chemical_list: D011093:Polyethylene Terephthalates