title: Skin fragility syndrome in a cat with multicentric follicular lymphoma.
abstract: An 11-year-old, spayed female domestic shorthair cat was presented for a right flank wound. On clinical examination, a single non-painful skin tear lesion with irregular edges was detected. During the examination, star-shaped cigarette paper-like skin lesions appeared spontaneously. An abdominal mass was also palpated. Feline skin fragility syndrome (FSFS) was suspected and a multicentric lymphoma was diagnosed by fine needle aspiration. The cat's condition declined and it died spontaneously. Post-mortem examination confirmed the diagnosis of lymphoma. Neoplastic lymphocytes were not observed in the skin. Histological analysis of the skin was consistent with the morphological aspects of FSFS. A possible direct link between the two conditions remains a matter of speculation, but this case report provides the first description of FSFS associated with multicentric follicular lymphoma. Thus, multicentric follicular lymphoma should be considered as a differential diagnosis in cats presenting with FSFS.
authors.affiliation: 1Dermatology Unit, Paris-Est University, National Veterinary School of Alfort, Maisons-Alfort, France.
authors.forename: Odile
authors.initials: O
authors.lastname: Crosaz
authors.forename: Federico
authors.initials: F
authors.lastname: Vilaplana-Grosso
authors.forename: Charline
authors.initials: C
authors.lastname: Alleaume
authors.forename: Nathalie
authors.initials: N
authors.lastname: Cordonnier
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Bedu-Leperlier
authors.forename: Geneviève
authors.initials: G
authors.lastname: Marignac
authors.forename: Blaise
authors.initials: B
authors.lastname: Hubert
authors.forename: Dan
authors.initials: D
authors.lastname: Rosenberg
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000209:etiology* / Q000473:pathology; D002415:Cats; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D008224:Lymphoma, Follicular / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D012871:Skin Diseases / Q000209:etiology / Q000473:pathology / Q000662:veterinary*