title: Copper-catalyzed regioselective reaction of internal alkynes and diaryliodonium salts.
abstract: The copper-catalyzed highly regioselective reaction of internal alkynes with diaryliodonium salts was achieved for the first time. α-Arylketones were obtained in moderate to good yields from arylpropargylic alcohols or aryl alkyl alkynes under mild conditions. It was found that the two kinds of substrates underwent two different arylation-oxygenation pathways under different reaction conditions based on deuterated experiments, controlling experiments, and spectroscopic analysis of reaction intermediates.
authors.affiliation: Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, Shanghai 200032, China.
authors.forename: Ze-Feng
authors.initials: ZF
authors.lastname: Xu
authors.forename: Chen-Xin
authors.initials: CX
authors.lastname: Cai
authors.forename: Jin-Tao
authors.initials: JT
authors.lastname: Liu
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001713:Biphenyl Compounds / Q000737:chemistry*; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D015394:Molecular Structure; D009861:Onium Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*; D012492:Salts / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D001713:Biphenyl Compounds; D009861:Onium Compounds; D012492:Salts; C031291:diphenyliodonium; D010165:Palladium; D003300:Copper