title: [cDNA cloning and sequence analysis of pluripotency genes in tree shrews (Tupaia belangeri)].
abstract: In this paper, partial sequences of the tree shrew (Tupaia belangeri) Klf4, Sox2, and c-Myc genes were cloned and sequenced, which were 382, 612, and 485 bp in length and encoded 127, 204, and 161 amino acids, respectively. Whereas, their cDNA sequence identities with those of human were 89%, 98%, and 89%, respectively. Their phylogenetic tree results indicated different topologies and suggested individual evolutional pathways. These results can facilitate further functional studies.
authors.affiliation: Faculty of Life Science and Technology, Kunming, China.
authors.forename: Cai-Yun
authors.initials: CY
authors.lastname: Wang
authors.forename: Yun-Han
authors.initials: YH
authors.lastname: Ma
authors.forename: Da-Jian
authors.initials: DJ
authors.lastname: He
authors.forename: Shi-Hua
authors.initials: SH
authors.lastname: Yang
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002417:Cattle; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics; D005260:Female; D006801:Humans; D000090062:Kruppel-Like Factor 4; D008297:Male; D008322:Mammals / Q000145:classification / Q000235:genetics; D051379:Mice; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D010802:Phylogeny; D011506:Proteins / Q000235:genetics*; D051381:Rats; D016415:Sequence Alignment; D014417:Tupaia / Q000235:genetics*
chemical_list: D018076:DNA, Complementary; C000715467:KLF4 protein, human; C000715468:Klf4 protein, mouse; C000715469:Klf4 protein, rat; D000090062:Kruppel-Like Factor 4; D011506:Proteins
keywords: Klf4; Sequence analysis; Sox2; Tree shrew; c-Myc