title: Increased serum nitric oxide and malondialdehyde levels in patients with acute intestinal amebiasis.
abstract: OBJECTIVE
  To determine the level of oxygen-nitrogen stress parameters in the pathogenesis of amebiasis.
  
  
  METHODS
  Twenty-four acute intestinal amebiasis patients and 20 healthy controls were enrolled in the present study. Serum malondialdehyde and nitric oxide levels were determined spectrophotometrically.
  
  
  RESULTS
  Serum malondialdehyde and nitric oxide levels were significantly higher in acute intestinal amebiasis patients than healthy controls (P<0.001).
  
  
  CONCLUSIONS
  These results suggest that oxidative and nitrosative stress may play a major role in tissue damage in acute intestinal amebiasis patients. Also these parameters can be used to supplement the conventional microscopic method for reliable diagnosis of intestinal amebiasis.
authors.affiliation: University of Gaziantep, Faculty of Medicine, Department of Biochemistry, Gaziantep, Turkey.
authors.forename: E S
authors.initials: ES
authors.lastname: Namıduru
authors.forename: M
authors.initials: M
authors.lastname: Tarakçıoğlu
authors.forename: M
authors.initials: M
authors.lastname: Namıduru
authors.forename: R
authors.initials: R
authors.lastname: Kocabaş
authors.forename: B
authors.initials: B
authors.lastname: Erbağcı
authors.forename: I
authors.initials: I
authors.lastname: Meram
authors.forename: I
authors.initials: I
authors.lastname: Karaoğlan
authors.forename: N
authors.initials: N
authors.lastname: Yılmaz
authors.forename: M
authors.initials: M
authors.lastname: Cekmen
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D004404:Dysentery, Amebic / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000097:blood*; D008875:Middle Aged; D009569:Nitric Oxide / Q000097:blood*; D044967:Serum / Q000737:chemistry*; D013053:Spectrophotometry; D055815:Young Adult
chemical_list: D015415:Biomarkers; D009569:Nitric Oxide; D008315:Malondialdehyde
keywords: Amebiasis; Malondialdehyde; Nitric oxide