title: The tert-butyl side chain: a powerful means to lock peptoid amide bonds in the cis conformation.
abstract: The very simple sterically hindered tert-butyl side chain exerts complete control over the peptoid amide geometry which only exists in the cis conformation. It is exemplified in NtBu glycine homo-oligomers and in linear oligopeptoids designed with an alternating cis-trans backbone amide pattern.
authors.affiliation: Clermont Université, Institut de Chimie de Clermont-Ferrand, BP 10448, F-63000 Clermont-Ferrand, France.
authors.forename: O
authors.initials: O
authors.lastname: Roy
authors.forename: C
authors.initials: C
authors.lastname: Caumes
authors.forename: Y
authors.initials: Y
authors.lastname: Esvan
authors.forename: C
authors.initials: C
authors.lastname: Didierjean
authors.forename: S
authors.initials: S
authors.lastname: Faure
authors.forename: C
authors.initials: C
authors.lastname: Taillefumier
mesh_terms: D000577:Amides / Q000737:chemistry*; D018360:Crystallography, X-Ray; D005998:Glycine / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D009842:Oligopeptides / Q000737:chemistry*; D034444:Peptoids / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D000577:Amides; D009842:Oligopeptides; D034444:Peptoids; D005998:Glycine