title: Pregnancy outcome in Budd Chiari Syndrome--a tertiary care centre experience.
abstract: BACKGROUND
  Pregnancy management is a crucial issue in women with Budd-Chiari Syndrome (BCS) and there are no established guidelines on the management.
  
  
  OBJECTIVE
  To report our experience of pregnancy outcome with BCS.
  
  
  METHODS
  We report outcome of 13 pregnancies in three women, with favourable outcome after the diagnosis of the condition and its treatment using intervention to bypass obstruction and anticoagulant therapy during pregnancy.
  
  
  RESULTS
  Three women had a total of 13 pregnancies; three after the diagnosis and decompressive treatment of the disease. Disease was diagnosed during index pregnancy in two women. Anticoagulation was given in all the three pregnancies (Robertson et al., Br J Haematol, 132:171-196, 2006). Pregnancies prior to diagnosis and treatment resulted in a live birth.
  
  
  CONCLUSIONS
  Pregnancy does not seem to be a contraindication in well treated and controlled BCS. Maternal outcome is good with close multidisciplinary surveillance. Foetal outcome, however, may still be poor due to underlying prothrombotic condition.
authors.affiliation: Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research, PGIMER, Chandigarh, 160012, India.
authors.forename: Neelam
authors.initials: N
authors.lastname: Aggarwal
authors.forename: Vanita
authors.initials: V
authors.lastname: Suri
authors.forename: Seema
authors.initials: S
authors.lastname: Chopra
authors.forename: Pooja
authors.initials: P
authors.lastname: Sikka
authors.forename: R K
authors.initials: RK
authors.lastname: Dhiman
authors.forename: Y K
authors.initials: YK
authors.lastname: Chawla
mesh_terms: D000328:Adult; D017130:Angioplasty; D000925:Anticoagulants / Q000627:therapeutic use*; D006502:Budd-Chiari Syndrome / Q000175:diagnosis / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis / Q000628:therapy*; D011256:Pregnancy Outcome; D011295:Prenatal Care / Q000379:methods*; D062606:Tertiary Care Centers; D016896:Treatment Outcome; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D014859:Warfarin; D006493:Heparin