title: Individual differences in inhibitory control--relationship between baseline activation in lateral PFC and an electrophysiological index of response inhibition.
abstract: The capacity to inhibit inappropriate responses is crucial for goal-directed behavior. Inhibiting such responses seems to come more easily to some of us than others, however. From where do these individual differences originate? Here, we measured 263 participants' neural baseline activation using resting electroencephalogram. Then, we used this stable neural marker to predict a reliable electrophysiological index of response inhibition capacity in the cued Continuous Performance Test, the NoGo-Anteriorization (NGA). Using a source-localization technique, we found that resting delta, theta, and alpha1 activity in the left middle frontal gyrus and resting alpha1 activity in the right inferior frontal gyrus were negatively correlated with the NGA. As a larger NGA is thought to represent better response inhibition capacity, our findings demonstrate that lower levels of resting slow-wave oscillations in the lateral prefrontal cortex, bilaterally, are associated with a better response inhibition capacity.
authors.affiliation: Social and Affective Neuroscience, Department of Psychology, University of Basel, Basel, Switzerland.
authors.forename: Bastian
authors.initials: B
authors.lastname: Schiller
authors.affiliation: Social and Affective Neuroscience, Department of Psychology, University of Basel, Basel, Switzerland.
authors.forename: Lorena R R
authors.initials: LR
authors.lastname: Gianotti
authors.affiliation: Social and Affective Neuroscience, Department of Psychology, University of Basel, Basel, Switzerland.
authors.forename: Kyle
authors.initials: K
authors.lastname: Nash
authors.affiliation: Social and Affective Neuroscience, Department of Psychology, University of Basel, Basel, Switzerland.
authors.forename: Daria
authors.initials: D
authors.lastname: Knoch
mesh_terms: D000513:Alpha Rhythm; D003700:Delta Rhythm; D004569:Electroencephalography; D056344:Executive Function / Q000502:physiology*; D005260:Female; D006801:Humans; D007175:Impulsive Behavior / Q000502:physiology*; D007206:Individuality; D008297:Male; D017397:Prefrontal Cortex / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology*; D012146:Rest; D013826:Theta Rhythm; D055815:Young Adult
keywords: NoGo-anteriorization; continuous performance test; prefrontal cortex; response inhibition; resting EEG