title: [Peripartum cardiomyopathy: interdisciplinary challenge].
abstract: Peripartum cardiomyopathy (PPCM) is a rare type of heart failure which presents towards the end of pregnancy or in the first 5 months after delivery. Depending on the geographical location the incidence is reported in the literature as 1:300 up to 1:15,000. There are a number of known risk factors, such as multiparity and age of the mother over 30 years. The symptoms of PPCM correspond to those of idiopathic cardiomyopathy. The diagnosis is mainly carried out using echocardiography which shows a clear reduction of systolic left ventricular function. The therapeutic approach is the same as for idiopathic cardiomyopathy and in this context it is absolutely necessary to show caution concerning the state of pregnancy and the resulting contraindications for therapeutic drugs. The prognosis is dependent on recovery from the heart failure during the first 6 months postpartum. The lethality of the disease is high and is given in the literature as up to 28 %. Because of its complexity PPCM is an interdisciplinary challenge. In the peripartum phase a close cooperation between the disciplines of cardiology, cardiac surgery, neonatology, obstetrics and anesthesiology is indispensable. For anesthesiology the most important aspects are the mostly advanced unstable hemodynamic condition of the mother and the planning and implementation of the perioperative management. This article presents the case of a patient in advanced pregnancy with signs of acute severe heart failure and a suspected diagnosis of PPCM. The patient presented as an emergency case and delivery of the child was carried out using peridural anesthesia with a stand-by life support machine.
authors.affiliation: Klinik und Poliklinik für Anästhesiologie, Zentrum für Anästhesiologie und Intensivmedizin, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20251 Hamburg, Deutschland. B.Loeser@uke.de
authors.forename: B
authors.initials: B
authors.lastname: Löser
authors.forename: S
authors.initials: S
authors.lastname: Tank
authors.forename: G
authors.initials: G
authors.lastname: Hillebrand
authors.forename: B
authors.initials: B
authors.lastname: Goldmann
authors.forename: W
authors.initials: W
authors.lastname: Diehl
authors.forename: D
authors.initials: D
authors.lastname: Biermann
authors.forename: J
authors.initials: J
authors.lastname: Schirmer
authors.forename: D A
authors.initials: DA
authors.lastname: Reuter
mesh_terms: D000328:Adult; D000765:Anesthesia, Conduction; D000768:Anesthesia, General; D002317:Cardiovascular Agents / Q000627:therapeutic use; D002585:Cesarean Section; D004562:Electrocardiography; D005260:Female; D006331:Heart Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000235:genetics / Q000628:therapy*; D006801:Humans; D016343:Monitoring, Intraoperative; D019990:Perioperative Care; D058725:Peripartum Period; D011182:Postoperative Care; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000235:genetics / Q000628:therapy*; D011379:Prognosis; D012307:Risk Factors
chemical_list: D002317:Cardiovascular Agents