title: Biotransformation of polydatin to resveratrol in Polygonum cuspidatum roots by highly immobilized edible Aspergillus niger and Yeast.
abstract: A new biotransformation method of producing resveratrol with co-immobilized edible Aspergillus niger and Yeast (AY) was investigated. The biotransformation conditions were optimized for the resveratrol production under 30 °C, pH 6.5, 2 days, liquid-solid ratio 12:1 (mL/g), the yield of resveratrol reached 33.45 mg/g, which increased 11-fold to that of untreated one. The conversion rate of polydatin reached 96.7%. The residual activity of immobilized microorganism was 83.2% after used for 15 runs. The developed method could be an effectively alternative biotransformation method for producing resveratrol from the plants.
authors.affiliation: State Engineering Laboratory of Bio-Resource Eco-Utilization, Northeast Forestry University, Harbin 150040, PR China.
authors.forename: Shuang
authors.initials: S
authors.lastname: Jin
authors.forename: Meng
authors.initials: M
authors.lastname: Luo
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Chun-jian
authors.initials: CJ
authors.lastname: Zhao
authors.forename: Cheng-bo
authors.initials: CB
authors.lastname: Gu
authors.forename: Chun-ying
authors.initials: CY
authors.lastname: Li
authors.forename: Yuan-gang
authors.initials: YG
authors.lastname: Zu
authors.forename: Yu-jie
authors.initials: YJ
authors.lastname: Fu
authors.forename: Yue
authors.initials: Y
authors.lastname: Guan
mesh_terms: D001234:Aspergillus niger / Q000378:metabolism*; D001711:Biotransformation; D018914:Cells, Immobilized / Q000378:metabolism; D045468:Fallopia japonica / Q000378:metabolism* / Q000382:microbiology; D005960:Glucosides / Q000378:metabolism*; D018517:Plant Roots / Q000378:metabolism* / Q000382:microbiology*; D059027:Recycling; D000077185:Resveratrol; D012441:Saccharomyces cerevisiae / Q000378:metabolism*; D013267:Stilbenes / Q000378:metabolism*
chemical_list: D005960:Glucosides; D013267:Stilbenes; D000077185:Resveratrol; C058229:polydatin