title: Recurrent endocrine mucin-producing sweat gland carcinoma in the eyelid.
abstract: Endocrine mucin-producing sweat gland carcinoma (EMPSGC) has recently been recognised as a low-grade carcinoma that almost always occurs on the eyelid. This carcinoma is very rare, with only 20 cases (including the present one) having been reported in the literature. EMPSGC is frequently found in association with invasive mucinous carcinoma. While EMPSGC treatments consist of a complete surgical removal, there has been no consensus regarding the surgical margin. Therefore, reports on surgical management of EMPSGC may potentially provide important therapeutic information. Here, we present a case of a 74-year-old man with EMPSGC of the eyelid that repeatedly recurred despite surgical treatments at another institution. After referral to our department, the patient underwent tumour excision. However, the specimen revealed a positive surgical margin and thus, he subsequently underwent a wider excision. There has been no sign of tumour recurrence or metastasis 6 months after his last operation. This article reviews the current literature and discusses the surgical management of EMPSGC.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Division of Anatomic and Surgical Pathology, Yokohama City University Hospital, Yokohama, Japan.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Koike
authors.forename: Taro
authors.initials: T
authors.lastname: Mikami
authors.forename: Jiro
authors.initials: J
authors.lastname: Maegawa
authors.forename: Toshinori
authors.initials: T
authors.lastname: Iwai
authors.forename: Hidefumi
authors.initials: H
authors.lastname: Wada
authors.forename: Shoji
authors.initials: S
authors.lastname: Yamanaka
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000473:pathology* / Q000601:surgery; D000368:Aged; D005142:Eyelid Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D013544:Sweat Gland Neoplasms / Q000473:pathology* / Q000601:surgery