title: Cardiac manifestations of Q fever infection: case series and a review of the literature.
abstract: BACKGROUND
  Q fever is a zoonotic disease caused by Coxiella burnetii, an uncommon intracellular bacterium found in livestock and domesticated dogs and cats. A minority of patients who acquire acute Q fever will subsequently develop chronic Q fever endocarditis, which often manifests in valvular insufficiency.
  
  
  METHODS
  We review recent literature and report the clinical presentation, treatment, and serology of three surgical patients with Q fever.
  
  
  CONCLUSIONS
  Three patients with Q fever were successfully treated at our institution, including the first known case of a C. burnetii infection manifesting in a pediatric patient with isolated aortic coarctation.
authors.affiliation: Department of Cardiothoracic Surgery, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
authors.forename: Tyler M
authors.initials: TM
authors.lastname: Gunn
authors.forename: Guy M
authors.initials: GM
authors.lastname: Raz
authors.forename: Joseph W
authors.initials: JW
authors.lastname: Turek
authors.forename: Robert Saeid
authors.initials: RS
authors.lastname: Farivar
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001017:Aortic Coarctation / Q000150:complications / Q000601:surgery; D001022:Aortic Valve Insufficiency / Q000601:surgery; D001705:Bioprosthesis; D004359:Drug Therapy, Combination; D004697:Endocarditis, Bacterial / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D007223:Infant; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis; D011778:Q Fever / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D012008:Recurrence
chemical_list: D000900:Anti-Bacterial Agents; D018501:Antirheumatic Agents; D006886:Hydroxychloroquine