title: The clinical investigation of disparity of nonalcoholic fatty liver disease in a Chinese occupational population in Taipei, Taiwan: experience at a teaching hospital.
abstract: The authors sought to explore the prevalence and factors related to nonalcoholic fatty liver disease (NAFLD) among occupational population in Taipei, Taiwan. A total of 8347 healthy adults voluntarily admitted to annual physical check-up. Blood samples and ultrasound-proved fatty liver sonography results were collected. The results showed that the prevalence of NAFLD was 48.4% and revealed a statistically significant increase with increasing population age. Males exhibited a greater prevalence of NAFLD than did females (57.8% vs 32.4%, P < .001). Using multiple logistic regression analysis, in addition to male gender, older age, higher body mass index, higher aspartate aminotransferase level, higher alanine aminotransferase level, presence of hypertension, presence of hyperuricemia, presence of hypercholesterolemia, higher fasting plasma glucose, and presence of hypertriglyceridemia were the significant factors associated with NAFLD. The differences in occupational professions were revealed. In conclusion, occupational populations are asymptomatic, and the diagnosis of NAFLD should be considered with older age, hyperuricemia, higher aspartate aminotransferase level, higher alanine aminotransferase level, and metabolic risk factors.
authors.affiliation: Fu-Jen Catholic University, Taipei, Taiwan.
authors.forename: Jui
authors.initials: J
authors.lastname: Wang
authors.affiliation: National Yang-Ming University, Taipei, Taiwan Central Clinic and Hospital, Taipei, Taiwan Jinan University, Guangzhou, China Hungchi Women & Children's Hospital, Taoyuan, Taiwan Qisda Corporation, Taipei, Taiwan.
authors.forename: Wei-Hsiu
authors.initials: WH
authors.lastname: Chiu
authors.affiliation: National Yang-Ming University, Taipei, Taiwan Taipei City Hospital, Taipei, Taiwan.
authors.forename: Ran-Chou
authors.initials: RC
authors.lastname: Chen
authors.affiliation: Fu-Jen Catholic University, Taipei, Taiwan.
authors.forename: Fu-Li
authors.initials: FL
authors.lastname: Chen
authors.affiliation: Fu-Jen Catholic University, Taipei, Taiwan Cheng-Hsin General Hospital, Tsaipei, Taiwan ch2876@chgh.org.tw.
authors.forename: Tao-Hsin
authors.initials: TH
authors.lastname: Tung
mesh_terms: D000328:Adult; D000367:Age Factors; D044466:Asian People; D001219:Aspartate Aminotransferases / Q000097:blood; D001786:Blood Glucose; D015992:Body Mass Index; D005260:Female; D006784:Hospitals, Teaching / Q000706:statistics & numerical data*; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D065626:Non-alcoholic Fatty Liver Disease / Q000097:blood / Q000000981:diagnostic imaging / Q000453:epidemiology*; D009790:Occupations / Q000706:statistics & numerical data*; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D013624:Taiwan / Q000453:epidemiology; D014463:Ultrasonography
chemical_list: D001786:Blood Glucose; D008055:Lipids; D001219:Aspartate Aminotransferases
keywords: nonalcoholic fatty liver disease; occupational population; prevalence