title: Perimyocarditis and myocardial infarction: A rare manifestation of Churg-Strauss syndrome.
abstract: The present article reports a case involving a 58-year-old man without cardiovascular risk factors who was admitted to hospital with acute coronary syndrome. Coronary angiography revealed high-grade arteriosclerotic stenosis of the mid-left anterior descending coronary artery and 80% proximal intermediate branch stenosis, which were treated using three drug-eluting stents. Churg-Strauss syndrome was diagnosed based on the patient's history of asthma, sinusitis, eosinophilia, nasal polyps, transient radiological pulmonary infiltrations and transient paresthesia over the left tibia, and eosinophilic pericardial effusion and eosinophilic infiltrations revealed in a myocardial biopsy. Treatment with prednisone was initiated, followed by treatment with cyclophosphamide. Eosinophil levels returned to normal after nine days of treatment. There is evidence that Churg-Strauss syndrome may promote arteriosclerosis.
authors.affiliation: Department of Internal Medicine, Zürich, Switzerland.
authors.forename: Christoph
authors.initials: C
authors.lastname: Gräni
authors.forename: Thomas
authors.initials: T
authors.lastname: Langenegger
authors.forename: Anja
authors.initials: A
authors.lastname: Fäh
authors.forename: David
authors.initials: D
authors.lastname: Kurz
authors.forename: Rainer
authors.initials: R
authors.lastname: Zbinden
authors.forename: David
authors.initials: D
authors.lastname: Ramsay
keywords: Acute coronary syndrome; Arteriosclerosis; Churg-Strauss syndrome; Eosinophilia; Myocardial infarction