title: MRI white matter lesions in pediatric migraine.
abstract: OBJECTIVE
  Studies have reported an association between migraine and white matter hyperintensities on T2-weighted brain magnetic resonance imaging (MRI) in adults. The aim of the present study was to evaluate white matter MRI brain findings in pediatric patients with migraine.
  
  
  METHODS
  The medical files and imaging scans of all 194 patients who underwent brain MRI at the headache clinic of a tertiary medical center in 2008-2011 were reviewed.
  
  
  RESULTS
  Mean age was 10.9 ± 3.5 years. Migraine was diagnosed in 131 patients and other disorders in 63. In the migraine group, findings on physical and laboratory examinations were within normal range. White matter lesions were identified on MRI scan in 14 children with migraine (10.6%) and none of the children with other disorders ( P  = 0.006). In 13/14 patients, the lesions were focal with a variable distribution; in the remaining patient, confluent periventricular hyperintensities were documented.
  
  
  CONCLUSIONS
  In a headache clinic of a tertiary pediatric medical center, white matter lesions are found in about 10% of pediatric patients with migraine.
authors.affiliation: Pediatric Headache Clinic, Ambulatory Day Care Hospitalization Unit, Schneider Children's Medical Center of Israel, Israel. eidlitz@post.tau.ac.il
authors.forename: Tal
authors.initials: T
authors.lastname: Eidlitz-Markus
authors.forename: Avraham
authors.initials: A
authors.lastname: Zeharia
authors.forename: Yishay
authors.initials: Y
authors.lastname: Haimi-Cohen
authors.forename: Osnat
authors.initials: O
authors.lastname: Konen
mesh_terms: D000293:Adolescent; D001921:Brain / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008881:Migraine Disorders / Q000473:pathology*; D009413:Nerve Fibers, Myelinated / Q000473:pathology*
keywords: MRI; migraine; pediatric; white matter lesions