title: Time-resolved X-ray PIV technique for diagnosing opaque biofluid flow with insufficient X-ray fluxes.
abstract: X-ray imaging is used to visualize the biofluid flow phenomena in a nondestructive manner. A technique currently used for quantitative visualization is X-ray particle image velocimetry (PIV). Although this technique provides a high spatial resolution (less than 10 µm), significant hemodynamic parameters are difficult to obtain under actual physiological conditions because of the limited temporal resolution of the technique, which in turn is due to the relatively long exposure time (~10 ms) involved in X-ray imaging. This study combines an image intensifier with a high-speed camera to reduce exposure time, thereby improving temporal resolution. The image intensifier amplifies light flux by emitting secondary electrons in the micro-channel plate. The increased incident light flux greatly reduces the exposure time (below 200 µs). The proposed X-ray PIV system was applied to high-speed blood flows in a tube, and the velocity field information was successfully obtained. The time-resolved X-ray PIV system can be employed to investigate blood flows at beamlines with insufficient X-ray fluxes under specific physiological conditions. This method facilitates understanding of the basic hemodynamic characteristics and pathological mechanism of cardiovascular diseases.
authors.affiliation: Department of Mechanical Engineering, Pohang University of Science and Technology, San 31, Hyojadong, Pohang, Republic of Korea.
authors.forename: Sung Yong
authors.initials: SY
authors.lastname: Jung
authors.forename: Han Wook
authors.initials: HW
authors.lastname: Park
authors.forename: Bo Heum
authors.initials: BH
authors.lastname: Kim
authors.forename: Sang Joon
authors.initials: SJ
authors.lastname: Lee
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D010781:Photography / Q000295:instrumentation*; D011859:Radiography / Q000295:instrumentation*; D012212:Rheology / Q000295:instrumentation*
keywords: X-ray imaging; high-speed imaging; particle image velocimetry