title: Hypoglycemic effect of Brassica juncea (seeds) on streptozotocin induced diabetic male albino rat.
abstract: OBJECTIVE
  To evaluate the hypoglycemic effect of Brassica juncea (seeds) on streptozotocin induced diabetic male albino rats.
  
  
  METHODS
  Hypoglycemic activity of Brassica juncea (seeds) aqueous extract at a dose of 250, 350 and 450 mg/kg body weight was evaluated. Adult male Swiss albino rats of six numbers in each group was undertaken for study and evaluated.
  
  
  RESULTS
  The serum insulin levels were recorded a significant depletion in all groups, short term as well as long term diabetic animals, when compared to that of normal animals. A significant dosage dependent augmenting effect of the seed extract on the serum insulin was recorded in both short term as well as long term groups.
  
  
  CONCLUSIONS
  The aqueous seed extract of Brassica juncea has potent hypoglycemic activity in male albino rat.
authors.affiliation: P.G. and Research Department of Zoology, Voorhees College, Physiology wing, Vellore-632 001(T.N.), India.
authors.forename: T
authors.initials: T
authors.lastname: Thirumalai
authors.forename: S Viviyan
authors.initials: SV
authors.lastname: Therasa
authors.forename: E K
authors.initials: EK
authors.lastname: Elumalai
authors.forename: E
authors.initials: E
authors.lastname: David
mesh_terms: D000818:Animals; D001835:Body Weight; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy*; D005951:Glucose Tolerance Test; D007004:Hypoglycemic Agents / Q000302:isolation & purification / Q000627:therapeutic use*; D007328:Insulin / Q000097:blood; D008297:Male; D009149:Mustard Plant / Q000737:chemistry*; D010936:Plant Extracts / Q000302:isolation & purification / Q000627:therapeutic use*; D017208:Rats, Wistar; D012639:Seeds / Q000737:chemistry
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin; D010936:Plant Extracts
keywords: Anti-diabetic; Ayurveda; Diabetes mellitus; Hypoglycemic; Insulin