title: Metastatic osteosarcoma to the stomach and ascending colon in a pediatric patient causing gastrointestinal hemorrhage.
abstract: Osteosarcoma metastasis to the gastrointestinal tract is a rare phenomenon (Horiuchi A, Watanabe Y, Yoshida M, et al.: Metastatic osteosarcoma in the jejunum with intussusception: report of a case. Surg Today 2007;37:440-2). Gastrointestinal metastases may cause intussusception, bowel obstruction, or hemorrhage (Horiuchi A, Watanabe Y, Yoshida M, et al.: Metastatic osteosarcoma in the jejunum with intussusception: report of a case. Surg Today 2007;37:440-2; Chondramohan K, Somanathan T, Kusamakumary P: Metastatic osteosarcoma causing intussusception. J Pediatr Surg 2003;38(E44):1-3; Hung GY, Chiou TJ, Hsieh YL, et al.: Intestinal metastasis causing intussusception in a patient treated for osteosarcoma with history of multiple metastases: a case report. Jpn J Clin Oncol 2001;31:165-167). We report a case of a 17 year old male with osteosarcoma metastatic to the stomach and ascending colon, causing significant chronic gastrointestinal hemorrhage. Surgical resection was performed due to persistent, symptomatic anemia. The patient is free of recurrent hemorrhage at 24months after metastectomy. Resection of gastrointestinal metastases of osteosarcoma offers good palliation of chronic hemorrhage related to these lesions.
authors.affiliation: Department of Pediatric Gastroenterology, The Cleveland Clinic, Cleveland, OH, USA. mosesj@ccf.org
authors.forename: Jonathan
authors.initials: J
authors.lastname: Moses
authors.forename: Neil
authors.initials: N
authors.lastname: Gibson
authors.forename: Thomas
authors.initials: T
authors.lastname: Plesec
authors.forename: Gregory
authors.initials: G
authors.lastname: Plautz
authors.forename: Marsha
authors.initials: M
authors.lastname: Kay
authors.forename: Oliver
authors.initials: O
authors.lastname: Soldes
mesh_terms: D000293:Adolescent; D001706:Biopsy; D001859:Bone Neoplasms / Q000473:pathology*; D003110:Colonic Neoplasms / Q000556:secondary* / Q000601:surgery*; D003937:Diagnosis, Differential; D005360:Fibula / Q000473:pathology*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology* / Q000601:surgery*; D006801:Humans; D008297:Male; D059146:Metastasectomy; D012516:Osteosarcoma / Q000556:secondary* / Q000601:surgery*; D013274:Stomach Neoplasms / Q000556:secondary* / Q000601:surgery*