title: Molecular concordance of concurrent Candida albicans candidemia and candiduria.
abstract: The significance of candiduria remains unclear. We correlated Candida albicans candidemia with candiduria by molecular genotyping. 33 pairs of concurrent blood and urine C. albicans isolates from 31 adult (≥ 18 years) were genotyped with infrequent-restriction-site PCR. The molecular concordance rates of three major genotypes were 100% for I, 82% for II, and 71% for III. The molecular concordance between concurrent C. albicans candidemia and candiduria was frequent. Our findings substantiate the importance of candiduria in appropriate clinical context as the majority of our patients were from intensive care units.
authors.affiliation: Department of Medicine, Division of Infectious Diseases, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan.
authors.forename: Po-Yen
authors.initials: PY
authors.lastname: Huang
authors.forename: Min-Hui
authors.initials: MH
authors.lastname: Hung
authors.forename: Shian-Sen
authors.initials: SS
authors.lastname: Shie
authors.forename: Lin-Hui
authors.initials: LH
authors.lastname: Su
authors.forename: Ke-Yuan
authors.initials: KY
authors.lastname: Chen
authors.forename: Jung-Jr
authors.initials: JJ
authors.lastname: Ye
authors.forename: Ping-Cheng
authors.initials: PC
authors.lastname: Chiang
authors.forename: Hsieh-Shong
authors.initials: HS
authors.lastname: Leu
authors.forename: Ching-Tai
authors.initials: CT
authors.lastname: Huang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002176:Candida albicans / Q000235:genetics* / Q000302:isolation & purification; D058387:Candidemia / Q000382:microbiology*; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D058889:Molecular Typing; D016533:Mycological Typing Techniques; D016133:Polymerase Chain Reaction; D014552:Urinary Tract Infections / Q000382:microbiology*