title: Advances in pediatric dehydration therapy.
abstract: OBJECTIVE
  To review the advances in the assessment, treatment, and evaluation of care for pediatric dehydration.
  
  
  RESULTS
  Recent studies have added new information across the spectrum of care for dehydration. Advances in the assessment of dehydration allow more accurate clinical evaluation, but do not help predict the treatment outcomes. Antiemetics as an adjunct to oral rehydration therapy have been proven well tolerated, efficacious, and cost-effective. Rapid, large-volume intravenous rehydration for outpatients with dehydration did not show any benefit over more standard regimens. Clinical guidelines incorporate all these aspects of care; however, physicians show poor adherence to the guidelines despite the evidence that guidelines improve outcomes and reduce cost.
  
  
  CONCLUSIONS
  Dehydration burdens the healthcare system worldwide. Through advances in its assessment, treatment with antiemetics and intravenous fluids, and standardization of practice with clinical guidelines, this burden could be reduced.
authors.affiliation: Division of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts 02215, USA. michelle.niescierenko@childrens.harvard.edu
authors.forename: Michelle
authors.initials: M
authors.lastname: Niescierenko
authors.forename: Richard
authors.initials: R
authors.lastname: Bachur
mesh_terms: D000932:Antiemetics / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D003681:Dehydration / Q000175:diagnosis / Q000628:therapy*; D005440:Fluid Therapy / Q000379:methods / Q000592:standards / Q000639:trends*; D006801:Humans; D017410:Practice Guidelines as Topic; D058996:Quality Improvement; D012720:Severity of Illness Index
chemical_list: D000932:Antiemetics