title: Chemical constituents from Solidago canadensis with hypolipidemic effects in HFD-fed hamsters.
abstract: Two new compounds, 8-dehydroxymethylvisanol (1) and 9-O-[3-O-acetyl-β-d-glucopyranosyl]-4-hydroxy-cinnamic acid (4), together with two known lignans, visanol (2) and 9-aldehydevibsanol (3), were isolated from the 80% EtOH extract of Solidago canadensis. The structures of the two new compounds were elucidated on the basis of 1D, 2D NMR, and mass spectral analysis. All the lignans exhibited moderate hypolipidemic activity in high-fat diet-fed hamsters.
authors.affiliation: Department of Cardiology, Jinqiu Hospital, Shenyang 11001, China. yhuang2012@sohu.com
authors.forename: Ying
authors.initials: Y
authors.lastname: Huang
authors.forename: Yan-Li
authors.initials: YL
authors.lastname: Hao
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Mai
mesh_terms: D000818:Animals; D002934:Cinnamates / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D006224:Cricetinae; D059305:Diet, High-Fat; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D000960:Hypolipidemic Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D017705:Lignans / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D036624:Solidago / Q000737:chemistry*
chemical_list: C582366:8-dehydroxymethylvisanol; C582367:9-O-(3-O-acetyl-beta-D-glucopyranosyl)-4-hydroxycinnamic acid; D002934:Cinnamates; D004365:Drugs, Chinese Herbal; D005960:Glucosides; D000960:Hypolipidemic Agents; D017705:Lignans