title: Evaluation of the BD MAX Cdiff assay for the detection of the toxin B gene of Clostridium difficile out of faecal specimens.
abstract: In this evaluation study, 180 faecal specimens were tested in parallel with the new BD MAX™ Cdiff assay, the Premier™ Toxins A&B, and toxigenic culture as reference method. BD MAX™ Cdiff presented a high sensitivity (96.0%) and specificity (99.4%) with a negative predictive value of 99.4%.
authors.affiliation: Institute of Hygiene, Microbiology and Environmental Medicine (IHME), Medical University of Graz, Universitaetsplatz 4, A-8010 Graz, Austria. eva.leitner@medunigraz.at
authors.forename: Eva
authors.initials: E
authors.lastname: Leitner
authors.forename: Michaela
authors.initials: M
authors.lastname: Einetter
authors.forename: Andrea J
authors.initials: AJ
authors.lastname: Grisold
authors.forename: Egon
authors.initials: E
authors.lastname: Marth
authors.forename: Gebhard
authors.initials: G
authors.lastname: Feierl
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001426:Bacterial Proteins / Q000235:genetics*; D001427:Bacterial Toxins / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D016360:Clostridioides difficile / Q000235:genetics*; D003967:Diarrhea / Q000175:diagnosis / Q000382:microbiology*; D004761:Enterocolitis, Pseudomembranous / Q000175:diagnosis / Q000382:microbiology*; D005243:Feces / Q000382:microbiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D025202:Molecular Diagnostic Techniques; D016133:Polymerase Chain Reaction; D012680:Sensitivity and Specificity; D055815:Young Adult
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins; C031815:toxB protein, Clostridium difficile