title: Effectiveness and reach of the FLU-FIT program in an integrated health care system: a multisite randomized trial.
abstract: OBJECTIVE
  We tested the effectiveness of offering home fecal immunochemical tests (FITs) during influenza vaccination clinics to increase colorectal cancer screening (CRCS).
  
  
  METHODS
  In a clinical trial at Kaiser Permanente Northern California influenza clinics in Redwood City, Richmond, South San Francisco, Union City, and Fresno, we randomly assigned influenza clinic dates to intervention (FIT offered) or control (FIT not offered) and compared subsequent CRCS activity.
  
  
  RESULTS
  Clinic staff provided FITs to 53.9% (1805/3351) of intervention patients aged 50 to 75 years. In the intent-to-treat analysis, 26.9% (900/3351) and 11.7% (336/2884) of intervention and control patients completed an FIT, respectively, within 90 days of vaccination (P ≤ .001). The adjusted odds ratio for completing FIT in the intervention versus the control arm was 2.75 (95% confidence interval = 2.40, 3.16). In the per protocol analysis, 35.4% (648/1830) of patients given FIT and 13.3% (588/4405) of patients not given FIT completed FIT within 90 days of vaccination (P ≤ .001).
  
  
  CONCLUSIONS
  This intervention may increase CRCS among those not reached by other forms of CRCS outreach. Future research should include the extent to which these programs can be disseminated and implemented nationally.
authors.affiliation: Department of Family and Community Medicine, University of California, San Francisco, CA94143-0900, USA. potterm@fcm.ucsf.edu
authors.forename: Michael B
authors.initials: MB
authors.lastname: Potter
authors.forename: Lynn M
authors.initials: LM
authors.lastname: Ackerson
authors.forename: Vicky
authors.initials: V
authors.lastname: Gomez
authors.forename: Judith M E
authors.initials: JM
authors.lastname: Walsh
authors.forename: Lawrence W
authors.initials: LW
authors.lastname: Green
authors.forename: Theodore R
authors.initials: TR
authors.lastname: Levin
authors.forename: Carol P
authors.initials: CP
authors.lastname: Somkin
mesh_terms: D000368:Aged; D002140:California; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000517:prevention & control; D019033:Delivery of Health Care, Integrated / Q000379:methods*; D055088:Early Detection of Cancer / Q000379:methods / Q000706:statistics & numerical data*; D005260:Female; D006293:Health Promotion / Q000379:methods*; D006801:Humans; D007252:Influenza Vaccines / Q000008:administration & dosage; D007251:Influenza, Human / Q000517:prevention & control*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009780:Occult Blood; D015397:Program Evaluation
chemical_list: D007252:Influenza Vaccines