title: Vascular endothelial growth factor-B expression in postischemic rat brain.
abstract: BACKGROUND
  Vascular endothelial growth factor-B (VEGF-B) protects against experimental stroke, but the effect of stroke on VEGF-B expression is uncertain.
  
  
  METHODS
  We examined VEGF-B expression by immunohistochemistry in the ischemic border zone 1-7 days after middle cerebral artery occlusion in rats.
  
  
  RESULTS
  VEGF-B immunoreactivity in the border zone was increased after middle cerebral artery occlusion and was associated with neurons and macrophages/microglia, but not astrocytes or endothelial cells.
  
  
  CONCLUSIONS
  These findings provide additional evidence for a role of VEGF-B in the endogenous response to cerebral ischemia.
authors.affiliation: Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA.
authors.forename: Lin
authors.initials: L
authors.lastname: Xie
authors.affiliation: Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA.
authors.forename: Xiaoou
authors.initials: X
authors.lastname: Mao
authors.affiliation: Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA ; Department of Pharmacology & Neuroscience, University of North Texas, 3500 Camp Bowie Boulevard, Fort Worth, TX 76107, USA.
authors.forename: Kunlin
authors.initials: K
authors.lastname: Jin
authors.affiliation: Buck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA.
authors.forename: David A
authors.initials: DA
authors.lastname: Greenberg
keywords: Ischemia; Stroke; Vascular endothelial growth factor-B (VEGF-B)