title: Posttraumatic intraocular pressure elevation and associated factors in patients with zone I open globe injuries.
abstract: BACKGROUND
  The object of this study was to determine factors that might be associated with intraocular pressure (IOP) elevation after anterior segment open globe injuries (zone I).
  
  
  METHODS
  Data were obtained from the records of 68 patients who experienced zone I open globe injury between January 2008 and October 2010. Group I was composed of patients with chronically elevated IOP of at least 21 mmHg within a 1-year follow-up period. The rate of posttraumatic IOP elevation and associated structural and functional risk factors were evaluated.
  
  
  RESULTS
  Of the 68 patients, 17 (25%) developed posttraumatic IOP elevation (Group 1). The mean age in group I was significantly older compared to group II (36.8±24.4 and 15.7±15.3 years, respectively [p=0.003]). Iris damage, postoperative inflammation, and use of long-term corticosteroids were significantly greater in group I (p<0.001, p<0.001, p=0.005 respectively). In group I, 13 of 17 patients (76.5%) had a wound size larger than 6 mm compared to only one patient (1/51, 2%) in group II, and the result was statistically significant (p<0.001). The size of wound larger than 6 mm also retained its statistical significance in multivariate analysis (p<0.001, odds ratio: 162.5).
  
  
  CONCLUSIONS
  This study shows a significant relationship between larger wound size (>6 mm) and elevation of IOP after trauma in zone I open globe injuries.
authors.affiliation: Department of Ophthalmology, Kastamonu State Hospital, Kastamonu, Turkey. druguracar@gmail.com
authors.forename: Uğur
authors.initials: U
authors.lastname: Acar
authors.forename: Elvin H
authors.initials: EH
authors.lastname: Yıldız
authors.forename: Damla
authors.initials: D
authors.lastname: Ergintürk Acar
authors.forename: Uğur Emrah
authors.initials: UE
authors.lastname: Altıparmak
authors.forename: Züleyha
authors.initials: Z
authors.lastname: Yalnız Akkaya
authors.forename: Ayşe
authors.initials: A
authors.lastname: Burcu
authors.forename: Nurten
authors.initials: N
authors.lastname: Unlü
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D015807:Eye Injuries, Penetrating / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007223:Infant; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000209:etiology* / Q000503:physiopathology*; D055815:Young Adult