title: An outbreak of Burkholderia cenocepacia associated with contaminated chlorhexidine solutions prepared in the hospital.
abstract: From October to December 2007, an outbreak of Burkholderia cenocepacia occurred in a secondary care hospital. The 19 B cenocepacia isolated from the patients, the chlorhexidine solutions of each different ward, and the purified water that diluted these solutions exhibited an identical pulsed-field gel electrophoresis pattern. Inadequate preparation of chlorhexidine solutions diluted with contaminated purified water may have resulted in an outbreak of B cenocepacia. Adequate preparation of chlorhexidine solutions should be emphasized.
authors.affiliation: Department of Internal Medicine, Daegu Fatima Hospital, Daegu, Republic of Korea.
authors.forename: Shinwon
authors.initials: S
authors.lastname: Lee
authors.forename: Seung Woo
authors.initials: SW
authors.lastname: Han
authors.forename: Gunwoo
authors.initials: G
authors.lastname: Kim
authors.forename: Do Young
authors.initials: DY
authors.lastname: Song
authors.forename: Je Chul
authors.initials: JC
authors.lastname: Lee
authors.forename: Ki Tae
authors.initials: KT
authors.lastname: Kwon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019121:Burkholderia Infections / Q000453:epidemiology* / Q000382:microbiology; D057508:Burkholderia cenocepacia / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D002710:Chlorhexidine; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D004196:Disease Outbreaks; D004202:Disinfectants; D004340:Drug Contamination; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D005838:Genotype; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged; D058889:Molecular Typing; D063728:Secondary Care Centers
chemical_list: D004202:Disinfectants; D002710:Chlorhexidine
keywords: Burkholderia cepacia complex; Disinfectants; Hospital outbreak; Water contamination