title: Salivary exoglycosidases in gestational diabetes .
abstract: BACKGROUND
  As exoglycosidases have been described as potential markers of salivary gland pathology, we decided to check the possibility of the use of these enzymes in the detection of salivary gland involvement in gestational diabetes.
  
  
  METHODS
  For this purpose diabetic pregnant women were compared to pregnant and non-pregnant healthy women. The activities of total HEX as well as GLU in the saliva were determined in duplicate according to Marciniak et al. The activities of GAL, FUC, and MAN in the saliva were determined in duplicate according to Zwierz et al.
  
  
  RESULTS
  It was found that the specific activities of exoglycosidases in the saliva of diabetic pregnant women significantly increased in comparison to healthy pregnant and non-pregnant women.
  
  
  CONCLUSIONS
  Increased specific activity of exoglycosidases suggests that gestational diabetes provokes structural/functional alterations in salivary glands and changes in the salivary glycoconjugates metabolism.
authors.affiliation: Department of Pedodontics, Medical University of Bialystok, 15-274 Bialystok, Poland. annazalewska74@yahoo.com
authors.forename: Anna
authors.initials: A
authors.lastname: Zalewska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Knaś
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Gumiężny
authors.forename: Marek
authors.initials: M
authors.lastname: Niczyporuk
authors.forename: Danuta
authors.initials: D
authors.lastname: Waszkiel
authors.forename: Adrian Wojciech
authors.initials: AW
authors.lastname: Przystupa
authors.forename: Wiesław
authors.initials: W
authors.lastname: Zarzycki
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000378:metabolism; D016640:Diabetes, Gestational / Q000175:diagnosis / Q000201:enzymology*; D005260:Female; D006001:Glycoconjugates / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000378:metabolism*; D006801:Humans; D008247:Lysosomes / Q000201:enzymology; D011247:Pregnancy; D012016:Reference Values; D012463:Saliva / Q000201:enzymology*; D012469:Salivary Glands / Q000378:metabolism; D055815:Young Adult
chemical_list: D015415:Biomarkers; D006001:Glycoconjugates; D006026:Glycoside Hydrolases