title: Relation between platelet indices and branch retinal vein occlusion in hypertensive patients.
abstract: BACKGROUND
  Branch retinal vein occlusion (BRVO) is the second most common retinal vascular disease after diabetic retinopathy. To date, the studies were unable to elucidate the mechanism of the thrombosis leading to the entity; particularly the relation between thrombocyte aggregation and retinal vein occlusion is still unclear. Mean platelet volume (MPV) is a determinant of rate of platelet production and activation, both of which are indices of function of platelets. The relation between MPV and BRVO has not been studied before. The aim was to evaluate MPV in BRVO.
  
  
  METHODS
  Forty patients were included in the study. Forty six age and sex matched hypertensive volunteers were recruited as the control group.
  
  
  RESULTS
  MPV values were significantly higher in BRVO patients compared with the control subjects (8.01 ± 0.79 vs 7.52 ± 0.32 fL, respectively; P < 0.001).
  
  
  CONCLUSIONS
  MPV is significantly higher in patients hypertensive BRVO patients and further investigations regarding its potentially use as a prognostic biomarker in patients with BRVO are needed.
authors.affiliation: Department of Ophthalmology, Duzce University Medical Faculty, Duzce, Turkey.
authors.forename: Halil Ibrahim
authors.initials: HI
authors.lastname: Onder
authors.forename: Ali Cagri
authors.initials: AC
authors.lastname: Kilic
authors.forename: Murat
authors.initials: M
authors.lastname: Kaya
authors.forename: Serkan
authors.initials: S
authors.lastname: Bulur
authors.forename: Elif
authors.initials: E
authors.lastname: Onder
authors.forename: Murat
authors.initials: M
authors.lastname: Tunc
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000473:pathology*; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D015539:Platelet Activation; D011446:Prospective Studies; D012169:Retinal Vein / Q000473:pathology*; D014689:Venous Insufficiency / Q000097:blood / Q000473:pathology*