title: Silver-catalyzed amidation of benzoylformic acids with tertiary amines via selective carbon-nitrogen bond cleavage.
abstract: A novel approach towards the synthesis of α-ketoamides using tertiary amines as nitrogen group sources via C-N bond cleavage has been developed. In the presence of Ag2CO3 and K2S2O8, α-keto acids reacted with tertiary amines to afford the corresponding α-ketoamides in good yields.
authors.affiliation: Department of Chemistry, Huaibei Normal University, Huaibei, Anhui 235000, P. R. China.
authors.forename: Xiaobin
authors.initials: X
authors.lastname: Zhang
authors.forename: Wenchao
authors.initials: W
authors.lastname: Yang
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
mesh_terms: D000577:Amides / Q000138:chemical synthesis* / Q000737:chemistry; D000588:Amines / Q000138:chemical synthesis / Q000737:chemistry*; D002384:Catalysis; D006038:Glyoxylates / Q000138:chemical synthesis / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis / Q000737:chemistry; D008333:Mandelic Acids / Q000138:chemical synthesis / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*
chemical_list: D000577:Amides; D000588:Amines; D006038:Glyoxylates; D007659:Ketones; D008333:Mandelic Acids; C012482:phenylglyoxylic acid; D012834:Silver