title: Transvitreal fibrinoid pseudoendophthalmitis after diabetic vitrectomy.
abstract: OBJECTIVE
  To describe the presentation and clinical course of noninfectious transvitreal fibrinoid response after vitrectomy for diabetic retinopathy.
  
  
  METHODS
  Data collected from charts included age, gender, surgical indication, preoperative and serial visual acuities, vitrectomy procedures, and postoperative clinical characteristics of involved eye.
  
  
  RESULTS
  Patients had a mean age of 65.6 years (51-82 years) with 5 women and 2 men. Patients had a range of diabetes duration from 4 to 27 years and a mean HgbA1C of 9.1 (5.8-14.1). Surgical indications included nonclearing vitreous hemorrhage (five), tractional retinal detachment (three), and clinically significant macular edema (one). All patients manifested transvitreal bands on postoperative Day 1 without anterior chamber reaction. Mean time to resolution of transvitreal bands was 8.75 days (4-15 days) on standard postoperative topical medications alone.
  
  
  CONCLUSIONS
  Transvitreal fibrinoid response after diabetic vitrectomy is a remarkable phenomenon that can occur in a wide variety of patients with diabetic retinopathy. It is important to differentiate this from infectious endophthalmitis, as this series of cases resolved spontaneously on topical medications alone.
authors.affiliation: Associated Retinal Consultants, Royal Oak, Michigan.
authors.forename: Caesar
authors.initials: C
authors.lastname: Luo
authors.forename: Alan
authors.initials: A
authors.lastname: Ruby
authors.forename: Melissa
authors.initials: M
authors.lastname: Neuwelt
authors.forename: George A
authors.initials: GA
authors.lastname: Williams
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003930:Diabetic Retinopathy / Q000601:surgery*; D009877:Endophthalmitis / Q000209:etiology* / Q000378:metabolism; D005260:Female; D005337:Fibrin / Q000378:metabolism*; D006801:Humans; D017075:Laser Coagulation; D008269:Macular Edema / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012163:Retinal Detachment / Q000601:surgery; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy / Q000009:adverse effects*; D014822:Vitreous Body / Q000378:metabolism* / Q000473:pathology; D014823:Vitreous Hemorrhage / Q000601:surgery
chemical_list: D005337:Fibrin