title: Iodine-131 meta-iodobezylguanidine single photon emission computed tomography/computerized tomography in diagnosis of neuro-endocrine tumors.
abstract: Metaiodobenzyl guanidine (MIBG) is a derivative of guanethidine and acts as an analogue of nor-epinephrine and is widely used in the imaging of tumors of neuro-endocrine origin. Iodine-123 MIBG has ideal imaging characteristics but is expensive with limited availability. Iodine-131 MIBG is widely used in India and is cheap. Hybrid single photon emission computed tomography (SPECT)/computerized tomography (CT) allows for anatomico-functional imaging and is being tried in MIBG studies. However, the experience with I-131 MIBG is limited. We present a pictorial assay of I-131 MIBG SPECT/CT findings in various MIBG avid tumors.
authors.affiliation: Department of Nuclear Medicine and PET, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Chidambaram Natrajan Balasubramanian
authors.initials: CN
authors.lastname: Harisankar
authors.forename: Bhagwant Rai
authors.initials: BR
authors.lastname: Mittal
authors.forename: Anish
authors.initials: A
authors.lastname: Bhattacharya
authors.forename: Raghava
authors.initials: R
authors.lastname: Kashyap
authors.forename: Anil
authors.initials: A
authors.lastname: Bhansali
keywords: Metaiodobenzyl guanidine; neuro-endocrine tumor; pheochromocytoma; single photon emission computed tomography/computerized tomography