title: Hepatitis E virus mixed infection in immunocompetent patient.
abstract: We detected 2 hepatitis E virus (HEV) strains in an acutely infected immunocompetent patient. Two populations of genotype 3 virus were observed in the hypervariable regions and open reading frames 2 and 3, indicating multiple infection with hepatitis E virus. Persons with mixed infections may provide the opportunity for virus recombination.
authors.affiliation: University of Edinburgh, Edinburgh, Scotland, United Kingdom. D.B.Smith@ed.ac.uk
authors.forename: Donald B
authors.initials: DB
authors.lastname: Smith
authors.forename: Jeff
authors.initials: J
authors.lastname: Vanek
authors.forename: Louise
authors.initials: L
authors.lastname: Wellington
authors.forename: Ingolfur
authors.initials: I
authors.lastname: Johannessen
authors.forename: Sandeep
authors.initials: S
authors.lastname: Ramalingam
authors.forename: Peter
authors.initials: P
authors.lastname: Simmonds
mesh_terms: D060085:Coinfection / Q000175:diagnosis* / Q000276:immunology / Q000821:virology; D005814:Genes, Viral; D005838:Genotype; D016751:Hepatitis E / Q000175:diagnosis* / Q000276:immunology / Q000821:virology; D016752:Hepatitis E virus / Q000235:genetics* / Q000276:immunology; D006801:Humans; D007121:Immunocompetence; D008297:Male; D008875:Middle Aged; D058889:Molecular Typing; D010802:Phylogeny; D017422:Sequence Analysis, DNA
keywords: Hepatitis E virus; immunocompetent; mixed infection; viruses