title: Hydroxyapatite-coated femoral stems in primary total hip arthroplasty: a meta-analysis of randomized controlled trials.
abstract: BACKGROUND
  Controversy exists over the use of hydroxyapatite (HA)-coated femoral stems in primary total hip arthroplasty (THA). We conducted a meta-analysis of randomized controlled trials (RCT) to compare the clinical and radiologic outcomes of primary THA using HA-coated versus non-HA-coated femoral stems.
  
  
  METHODS
  Databases including MEDLINE, EMBASE and the Cochrane Library were searched to find relevant RCTs comparing HA-coated versus non-HA-coated femoral stems in primary THA. Data analyses were performed using RevMan 5.0 (The Cochrane Collaboration).
  
  
  RESULTS
  Seven studies (792 hips) met the inclusion criteria. The pooled weighted mean difference (WMD) for the postoperative Harris hip score was 3.04 (95% CI: -4.47 to 10.54, P = 0.43). The cumulative risk ratios (RR) for the presence of endosteal condensation and radioactive lines were 1.02 (95% CI: 0.93 to 1.12, P = 0.64) and 1.01 (95% CI: 0.90 to 1.14, P = 0.81), respectively.
  
  
  CONCLUSIONS
  This meta-analysis demonstrates that the use of HA-coated femoral stems in primary THA has no clinical or radiological benefits.
authors.affiliation: Department of Orthopedic Surgery, The Affiliated Ruikang Hospital of Guangxi Traditional Chinese Medical College, 530011 Nanning, China. azhen807914@hotmail.com
authors.forename: Shuzhen
authors.initials: S
authors.lastname: Li
authors.forename: Baohua
authors.initials: B
authors.lastname: Huang
authors.forename: Yueping
authors.initials: Y
authors.lastname: Chen
authors.forename: Hui
authors.initials: H
authors.lastname: Gao
authors.forename: Qie
authors.initials: Q
authors.lastname: Fan
authors.forename: Jinmin
authors.initials: J
authors.lastname: Zhao
authors.forename: Wei
authors.initials: W
authors.lastname: Su
mesh_terms: D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000295:instrumentation* / Q000379:methods; D017886:Durapatite / Q000008:administration & dosage*; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D017886:Durapatite