title: Searching for unpublished data for Cochrane reviews: cross sectional study.
abstract: OBJECTIVE
  To describe the experiences of authors of Cochrane reviews in searching for, getting access to, and using unpublished data.
  
  
  METHODS
  Cross sectional study.
  
  
  METHODS
  Cochrane reviews.
  
  
  METHODS
  2184 corresponding authors of Cochrane reviews as of May 2012.
  
  
  METHODS
  Frequencies of responses to open ended and closed questions in an online survey.
  
  
  RESULTS
  Of 5915 authors contacted by email, 2184 replied (36.9% response rate). Of those, 1656 (75.8%) had searched for unpublished data. In 913 cases (55.1% of 1656), new data were obtained and we received details about these data for 794 data sources. The most common data source was "trialists/investigators," accounting for 73.9% (n=587) of the 794 data sources. Most of the data were used in the review (82.0%, 651/794) and in 53.4% (424/794) of cases data were provided in less than a month. Summary data were most common, provided by 50.8% (403/794) of the data sources, whereas 20.5% (163/794) provided individual patient data. In only 6.3% (50/794) of cases were data reported to have been obtained from the manufacturers, and this group waited longer and had to make more contacts to get the data. The data from manufacturers were less likely to be for individual patients and less likely to be used in the review. Data from regulatory agencies accounted for 3.0% (24/794) of the obtained data.
  
  
  CONCLUSIONS
  Most authors of Cochrane reviews who searched for unpublished data received useful information, primarily from trialists. Our response rate was low and the authors who did not respond were probably less likely to have searched for unpublished data. Manufacturers and regulatory agencies were uncommon sources of unpublished data.
authors.affiliation: The Nordic Cochrane Centre, Rigshospitalet, Dept 7810, Blegdamsvej 9, DK-2100 Copenhagen Ø, Denmark. js@cochrane.dk
authors.forename: Jeppe Bennekou
authors.initials: JB
authors.lastname: Schroll
authors.forename: Lisa
authors.initials: L
authors.lastname: Bero
authors.forename: Peter C
authors.initials: PC
authors.lastname: Gøtzsche
mesh_terms: D001319:Authorship; D003430:Cross-Sectional Studies; D003625:Data Collection; D006801:Humans; D011643:Publishing; D057386:Search Engine; D011795:Surveys and Questionnaires