title: Headspace single-drop microextraction gas chromatography mass spectrometry for the analysis of volatile compounds from herba asari.
abstract: A rapid headspace single-drop microextraction gas chromatography mass spectrometry (SDME-GC-MS) for the analysis of the volatile compounds in Herba Asari was developed in this study. The extraction solvent, extraction temperature and time, sample amount, and particle size were optimized. A mixed solvent of n-tridecane and butyl acetate (1 : 1) was finally used for the extraction with sample amount of 0.750 g and 100-mesh particle size at 70°C for 15 min. Under the determined conditions, the pound samples of Herba Asari were directly applied for the analysis. The result showed that SDME-GC-MS method was a simple, effective, and inexpensive way to measure the volatile compounds in Herba Asari and could be used for the analysis of volatile compounds in Chinese medicine.
authors.affiliation: National Institutes for Food and Drug Control, No. 2, Tiantan Xili, Beijing 100050, China.
authors.forename: Guan-Jie
authors.initials: GJ
authors.lastname: Wang
authors.forename: Li
authors.initials: L
authors.lastname: Tian
authors.forename: Yu-Ming
authors.initials: YM
authors.lastname: Fan
authors.forename: Mei-Ling
authors.initials: ML
authors.lastname: Qi