title: [Effect of propranolol gel on infantile hemangiomas].
abstract: OBJECTIVE
  To evaluate the efficacy and security of propranolol gel in treatment of Infantile hemangiomas.
  
  
  METHODS
  51 consecutive infants with hemangiomas from October 2010 to September 2011 in Department of General Surgery Fuzhou General Hospital of Nanjing Military Command were treated with propranolol hydrochloride 3% gel. Changes in hemangioma size, texture, color, tumor blood flow peak were recorded.
  
  
  RESULTS
  The results were evaluated using Achauer system, responses of IHs to propranolol were considered scale I (poor) in 4 patient (17.24%), scale II (moderate) in 18 patients (24.14%), scale III (good) in 22 patients (44.83%) and scale IV (excellent) in 7 patients (13.79%). The response of superficial hemangiomas was significantly better than other hemangiomas (P < 0.05), and no significant differences in response among different primary sites (P > 0.05).
  
  
  CONCLUSIONS
  Topical use of propranolol hydrochloride 3% gel is an effective option for superficial hemangiomas.
authors.affiliation: Department of General Surgery, Fuzhou General Hospital of Nanjing Military Command, Fuzhou 350025, China.
authors.forename: Ya-Nan
authors.initials: YN
authors.lastname: Zhai
authors.forename: Hong-Tao
authors.initials: HT
authors.lastname: Song
authors.forename: Shao-Quan
authors.initials: SQ
authors.lastname: Chen
authors.forename: Min-Xin
authors.initials: MX
authors.lastname: Zhang
authors.forename: Cheng-Jin
authors.initials: CJ
authors.lastname: Li
authors.forename: Yin
authors.initials: Y
authors.lastname: Xia
authors.forename: Lie
authors.initials: L
authors.lastname: Wang
mesh_terms: D005260:Female; D018324:Hemangioma, Capillary / Q000188:drug therapy*; D006801:Humans; D020100:Hydrogels; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011433:Propranolol / Q000008:administration & dosage / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D020100:Hydrogels; D011433:Propranolol