title: Magnetically-Assisted Remote Controlled Microcatheter Tip Deflection under Magnetic Resonance Imaging.
abstract: X-ray fluoroscopy-guided endovascular procedures have several significant limitations, including difficult catheter navigation and use of ionizing radiation, which can potentially be overcome using a magnetically steerable catheter under MR guidance. The main goal of this work is to develop a microcatheter whose tip can be remotely controlled using the magnetic field of the MR scanner. This protocol aims to describe the procedures for applying current to the microcoil-tipped microcatheter to produce consistent and controllable deflections. A microcoil was fabricated using laser lathe lithography onto a polyimide-tipped endovascular catheter. In vitro testing was performed in a waterbath and vessel phantom under the guidance of a 1.5-T MR system using steady-state free precession (SSFP) sequencing. Various amounts of current were applied to the coils of the microcatheter to produce measureable tip deflections and navigate in vascular phantoms. The development of this device provides a platform for future testing and opportunity to revolutionize the endovascular interventional MRI environment.
authors.affiliation: Department of Radiology and Biomedical Imaging, University of California, San Francisco, USA. steven.hetts@ucsf.edu
authors.forename: Steven W
authors.initials: SW
authors.lastname: Hetts
authors.forename: Maythem
authors.initials: M
authors.lastname: Saeed
authors.forename: Alastair
authors.initials: A
authors.lastname: Martin
authors.forename: Prasheel
authors.initials: P
authors.lastname: Lillaney
authors.forename: Aaron
authors.initials: A
authors.lastname: Losey
authors.forename: Erin Jeannie
authors.initials: EJ
authors.lastname: Yee
authors.forename: Ryan
authors.initials: R
authors.lastname: Sincic
authors.forename: Loi
authors.initials: L
authors.lastname: Do
authors.forename: Lee
authors.initials: L
authors.lastname: Evans
authors.forename: Vincent
authors.initials: V
authors.lastname: Malba
authors.forename: Anthony F
authors.initials: AF
authors.lastname: Bernhardt
authors.forename: Mark W
authors.initials: MW
authors.lastname: Wilson
authors.forename: Anand
authors.initials: A
authors.lastname: Patel
authors.forename: Ronald L
authors.initials: RL
authors.lastname: Arenson
authors.forename: Curtis
authors.initials: C
authors.lastname: Caton
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Cooke
mesh_terms: D006328:Cardiac Catheterization / Q000295:instrumentation* / Q000379:methods*; D060526:Magnetic Fields; D018810:Magnetic Resonance Angiography / Q000295:instrumentation* / Q000379:methods*; D062666:Vascular Access Devices