title: Salvage CT-guided transgluteal cryoablation for locally recurrent prostate cancer: initial experiences.
abstract: Technical feasibility of a computed tomography (CT)-guided transgluteal approach for salvage cryoablation of inoperable locally recurrent prostate cancer was evaluated retrospectively. Five procedures were performed under general anesthesia in five patients previously treated with radiation therapy. Median age was 64 years, and average pretreatment prostate-specific antigen (PSA) level was 2.77 ng/dL (range, 0.56-4.23 ng/dL). Each cryoablation procedure was completed in one session. No complications were reported. Mean 3-month and 6-month PSA levels were 0.35 ng/dL (range, 0.16-0.54 ng/dL) and 0.51 ng/dL (range, 0.09-0.94 ng/dL), respectively, representing mean decreases of 84% (range, 71%-92%) and 81% (range, 78%-84%), respectively. Salvage CT-guided transgluteal cryoablation of the prostate therefore appears technically feasible.
authors.affiliation: Department of Radiology, Pellegrin Hospital, Place Amélie Raba Léon, 33076 Bordeaux, France. francois.cornelis@chu-bordeaux.fr
authors.forename: Francois
authors.initials: F
authors.lastname: Cornelis
authors.forename: Marion
authors.initials: M
authors.lastname: Havez
authors.forename: Yann
authors.initials: Y
authors.lastname: Le Bras
authors.forename: Edouard
authors.initials: E
authors.lastname: Descat
authors.forename: Pierre
authors.initials: P
authors.lastname: Richaud
authors.forename: Nicolas
authors.initials: N
authors.lastname: Grenier
mesh_terms: D000368:Aged; D002081:Buttocks / Q000000981:diagnostic imaging; D003452:Cryosurgery / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging* / Q000601:surgery*; D010865:Pilot Projects; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D012189:Retrospective Studies; D025321:Surgery, Computer-Assisted / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome