title: Giant anterior chest wall basal cell carcinoma: a reconstructive challenge and review of the literature.
abstract: Giant basal cell carcinomas (GBCC) are rare, accounting for <1% of BCCs. Those occurring on the anterior chest wall are a very rare subset that brings particular reconstructive challenges. We describe a 75-year-old man whose 13.5 cm diameter ulcerating GBCC on his left anterior chest came to medical attention following a fall. The lesion was resected en-bloc with adjacent ribs, and reconstructed with an omental flap, superiorly pedicled vertical rectus abdominus myocutaneous (VRAM) flap and split skin grafting. While the myriad reasons for delayed presentation of giant cutaneous malignancies are well documented, the complex nature of reconstruction and requirement for an integrated multidisciplinary approach are less so. It is of importance to note that the cicatricial nature of these lesions may result in a much larger defect requiring reconstruction than appreciated prior to resection. Documented cases of anterior chest wall GBCC and the treatment strategies employed are reviewed.
authors.affiliation: Department of Plastic Surgery, Frenchay Hospital, Bristol, UK. james.warbrick-smith@nbt.nhs.uk
authors.forename: James
authors.initials: J
authors.lastname: Warbrick-Smith
authors.forename: Jennifer K
authors.initials: JK
authors.lastname: O'Neill
authors.forename: Paul
authors.initials: P
authors.lastname: Wilson
mesh_terms: D000368:Aged; D002280:Basal Cell Carcinoma / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D008297:Male; D009852:Omentum / Q000637:transplantation; D019651:Plastic Surgery Procedures / Q000379:methods*; D017568:Rectus Abdominis / Q000637:transplantation; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery*; D013524:Surgical Flaps; D035441:Thoracic Wall / Q000473:pathology* / Q000601:surgery*