title: Gamma Probe Guided Minimally Invasive Parathyroidectomy without Quick Parathyroid Hormone Measurement in the Cases of Solitary Parathyroid Adenomas.
abstract: OBJECTIVE
  In this study, our aim was to study the efficiency of gamma probe guided minimally invasive parathyroidectomy (GP-MIP), conducted without the intra-operative quick parathyroid hormone (QPTH) measurement in the cases of solitary parathyroid adenomas (SPA) detected with USG and dual phase 99mTc-MIBI parathyroid scintigraphy (PS) in the preoperative period.
  
  
  METHODS
  This clinical study was performed in 31 SPA patients (27 female, 4 male; mean age 51±11years) between February 2006 and January 2009. All patients were operated within 30 days after the detection of the SPA with dual phase 99mTc-MIBI PS and USG. The GP-MIP was done 90-120 min after the iv injection of 740 MBq 99mTc-MIBI. In all cases, except 1 patient, the GP-MIP was performed under local anesthesia; due to the enormity of size of SPA, then general anesthesia is chosen.
  
  
  RESULTS
  The operation time was 30-60 min, mean 38,2±7 min. In the first postoperative day, there was a more than 50% decrease in PTH levels in all patients and all but one had normal serum calcium levels. Transient hypocalcemia was detected in one patient.
  
  
  CONCLUSIONS
  GP-MIP without intra-operative QPTH measurement is a suitable method in the surgical treatment of SPA detected by dual phase 99mTc-MIBI PS and USG.
  
  
  BACKGROUND
  None declared.
authors.affiliation: Trabzon Kanuni Training and Research Hospital, Department of Nuclear Medicine, Trabzon, Turkey.
authors.forename: Savaş
authors.initials: S
authors.lastname: Karyağar
authors.forename: Sevda S
authors.initials: SS
authors.lastname: Karyağar
authors.forename: Orhan
authors.initials: O
authors.lastname: Yalçın
authors.forename: Enis
authors.initials: E
authors.lastname: Yüney
authors.forename: Mehmet
authors.initials: M
authors.lastname: Mülazımoğlu
authors.forename: Tevfik
authors.initials: T
authors.lastname: Ozpaçacı
authors.forename: Oğuzhan
authors.initials: O
authors.lastname: Karatepe
authors.forename: Yaşar
authors.initials: Y
authors.lastname: Ozdenkaya
keywords: Solitary parathyroid Adenoma; gamma probe; parathyroidectomy