title: [Pronostic value of ureteral location of upper tract urinary carcinoma].
abstract: OBJECTIVE
  The aim of this study was to evaluate the prognostic significance of the ureteral location of the upper tract urinary carcinoma (UTUC).
  
  
  METHODS
  Between January 1998 and December 2007, 161 patients with UTUC were operated in our center. Tumors were located on renal pelvis in 51% of cases, on the ureter in 34% of cases and in both locations in 15% of cases. Nephroureterectomy was performed in 79.5% of cases (128/161) whereas a conservative treatment was performed in 20.5% of cases (33/161).
  
  
  RESULTS
  In our series, 29.8% of patients had primary bladder cancer and 14.3% had synchronous bladder tumor. At a median follow-up of 42.5 months, 38.6% of patients developed bladder recurrence and 4.8% developed controlateral upper tract tumor. In multivariate analysis, ureteral location and existence of synchronous bladder tumor were independent prognostic factors of bladder recurrence (P=0.009 and P=0.025, respectively). Multivariate analysis retained T-stage and ureteral location as independent prognostic factors in both overall and disease-free survival (P=0.002 and P=0.0008 respectively for ureteral location).
  
  
  CONCLUSIONS
  Ureteral location was an independent prognostic factor of bladder recurrence and was associated with a poorer prognosis.
authors.affiliation: Service d'urologie, hôpital Cochin, université Paris-V - Paris Descartes, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France. constance.legoux@gmail.com
authors.forename: C
authors.initials: C
authors.lastname: Le Goux
authors.forename: G
authors.initials: G
authors.lastname: Pignot
authors.forename: D
authors.initials: D
authors.lastname: Amsellem-Ouazana
authors.forename: A
authors.initials: A
authors.lastname: Vieillefond
authors.forename: M
authors.initials: M
authors.lastname: Peyromaure
authors.forename: T
authors.initials: T
authors.lastname: Flam
authors.forename: B
authors.initials: B
authors.lastname: Debré
authors.forename: M
authors.initials: M
authors.lastname: Zerbib
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000401:mortality*; D007682:Kidney Pelvis; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000401:mortality*; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D014513:Ureter; D014516:Ureteral Neoplasms / Q000401:mortality*