title: Improvement of visual acuity after transcorneal electrical stimulation in case of Best vitelliform macular dystrophy.
abstract: OBJECTIVE
  To report an improvement of the visual acuity after transcorneal electrical stimulation (TES) in a case of Best vitelliform macular dystrophy (BVMD).
  
  
  METHODS
  A 26-year-old woman diagnosed with BVMD presented with reduced vision. Her best corrected visual acuity (BCVA) was reduced to 20/200 in the right eye, and TES was performed once a month for two sessions. The current of the biphasic pulses (anodic first; duration, 10 msec; frequency, 20 Hz) was delivered using a DTL-electrode, and the duration of the TES was 30 min.
  
  
  RESULTS
  The BCVA in the right eye slowly improved after the TES, and 6 months later the BCVA was 20/25. The results of Humphrey visual field tests (VF) and multifocal ERGs (mfERGs) were only slightly changed. Two years later, the BCVA decreased, and it was improved again after another session of TES with the same parameters of the electrical pulses.
  
  
  CONCLUSIONS
  The improvement of the visual acuity in our case of BVMD indicates that TES should be tried in other cases of retinal dystrophy. Further clinical and laboratory studies on TES are needed.
authors.affiliation: Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Ozeki
authors.forename: Kei
authors.initials: K
authors.lastname: Shinoda
authors.forename: Hisao
authors.initials: H
authors.lastname: Ohde
authors.forename: Susumu
authors.initials: S
authors.lastname: Ishida
authors.forename: Kazuo
authors.initials: K
authors.lastname: Tsubota
mesh_terms: D000328:Adult; D003315:Cornea / Q000502:physiology; D004599:Electric Stimulation Therapy; D004596:Electroretinography; D005260:Female; D006801:Humans; D010719:Phosphenes; D012160:Retina / Q000503:physiopathology; D041623:Tomography, Optical Coherence; D014786:Vision Disorders / Q000503:physiopathology / Q000628:therapy*; D014792:Visual Acuity / Q000502:physiology*; D058609:Visual Field Tests; D014794:Visual Fields / Q000502:physiology; D057826:Vitelliform Macular Dystrophy / Q000503:physiopathology / Q000628:therapy*