title: [Fall risk and fracture. Drugs that affect the fall or fracture].
abstract: The relationship between the fall and types of hypnotics was studied. The incidence of falls on hypnotics was lower in subjects on ultra-short-acting type, such as Myslee tablet (1.6%) than in those on short-acting type (5.0 to 6.8%) drugs. For Myslee tablet, the incidences were similar in the daytime and the nighttime, but for short-acting hypnotics, the incidence was higher in the daytime than in the nighttime, suggesting a persistent diurnal effect. In order to prevent falls, we recommend to physicians prescribe Myslee tablet whenever possible. Afterwards, the number of patients who experienced falls decreased by 40%. The hypnotics was effected the severity of the injury after falling down. The odds ratios of different types of hypnotics to Myslee tablet on severe injury after falling as follows : Depas tablet having the highest odds ratioat 48, Rohypnol tablet coming in second at 38, respectively.
authors.affiliation: Pharmacentical Department, Tokyo Teisin Hospital, Japan.
authors.forename: Michiteru
authors.initials: M
authors.lastname: Ohtani
mesh_terms: D000058:Accidental Falls / Q000517:prevention & control; D064420:Drug-Related Side Effects and Adverse Reactions; D050723:Fractures, Bone / Q000139:chemically induced; D006801:Humans; D015994:Incidence; D016017:Odds Ratio; D012307:Risk Factors