title: [Optimization of high flip angle for late gadolinium enhancement magnetic resonance imaging by phase-sensitive inversion recovery sequence].
abstract: This study focuses on optimization of the flip angle (FA) of phase-sensitive inversion recovery (PSIR) reconstruction (PSIR-FA) to achieve improved tissue contrast. Intensity normalization removes the larger variations in image intensity caused by falloff, thus improving the visualization of tissue contrast. We evaluated tissue contrast for images in healthy volunteers using the phantom influence of T1 relaxation and FA. T1 relaxation is improved due to the T1(*) effect and enables a high PSIR-FA to be set. The contrast-to-noise ratio (CNR) of the PSIR-FA 20° image is good, since magnetization is almost fully restored to normal. The usefulness of PSIR-FA 20 images was proved statistically. PSIR-FA 20° shows improved tissue contrast as a result of the high accuracy of intensity normalization.
authors.affiliation: Department of Radiology, Nippon Medical Main Hospital.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yoshizawa
authors.forename: Toshio
authors.initials: T
authors.lastname: Tsuchihashi
authors.forename: Satoshi
authors.initials: S
authors.lastname: Harashina
authors.forename: Akira
authors.initials: A
authors.lastname: Yoshimi
authors.forename: Kenichi
authors.initials: K
authors.lastname: Shimokawa
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Matsumura
mesh_terms: D005682:Gadolinium; D006801:Humans; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019047:Phantoms, Imaging
chemical_list: D005682:Gadolinium