title: Combined intraoperative use of Diltiazem and N-acetylcystein increases myocardial damage and oxidative stress during off-pump cardiac surgery.
authors.affiliation: Department of Anaesthesiology, University Hospital, Strasbourg, France. Electronic address: annick.Steib@chru-strasbourg.fr.
authors.forename: Annick
authors.initials: A
authors.lastname: Steib
authors.forename: Olivier
authors.initials: O
authors.lastname: Collange
authors.forename: Astrid
authors.initials: A
authors.lastname: Quessard
authors.forename: François
authors.initials: F
authors.lastname: Levy
authors.forename: Michèle
authors.initials: M
authors.lastname: Zeisser
authors.forename: Anne-Laure
authors.initials: AL
authors.lastname: Charles
authors.forename: Calin
authors.initials: C
authors.lastname: Oltean
authors.forename: Jean-Georges
authors.initials: JG
authors.lastname: Kretz
authors.forename: Bernard
authors.initials: B
authors.lastname: Geny
authors.forename: Jacques
authors.initials: J
authors.lastname: Borg
mesh_terms: D000111:Acetylcysteine / Q000008:administration & dosage / Q000009:adverse effects*; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000009:adverse effects*; D047549:Coronary Artery Bypass, Off-Pump; D004110:Diltiazem / Q000008:administration & dosage / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D016166:Free Radical Scavengers / Q000008:administration & dosage / Q000009:adverse effects*; D006321:Heart / Q000187:drug effects*; D006801:Humans; D007430:Intraoperative Care; D018384:Oxidative Stress / Q000187:drug effects*; D015427:Reperfusion Injury / Q000517:prevention & control
chemical_list: D002121:Calcium Channel Blockers; D016166:Free Radical Scavengers; D004110:Diltiazem; D000111:Acetylcysteine
keywords: Acetylcystein; Cardiac surgery; Diltiazem; Ischaemia–reperfusion injury; Oxidative stress markers; Troponin