title: Cytocompatibility and mechanical properties of novel porous 316 L stainless steel.
abstract: Novel 316 L stainless steel (SS) foam with 85% porosity and an open pore diameter of 70-440 μm was developed for hard tissue application. The foam sheet with a 200-μm diameter had superior cell proliferation and penetration as identified through in vitro experiments. Calcification of human osteosarcoma cells in the SS foam was observed. Multi-layered foam preparation is a potential alternative technique that satisfies multi-functional requirements such as cell penetration and binding strength to the solid metal. In tensile tests, Young's modulus and the strength of the SS foam were 4.0 GPa and 11.2 MPa respectively, which is comparable with human cancellous bone.
authors.affiliation: Mitsubishi Material Corp., Saitama, 330-8508, Japan. kkato@mmc.co.jp
authors.forename: Komei
authors.initials: K
authors.lastname: Kato
authors.forename: Akiko
authors.initials: A
authors.lastname: Yamamoto
authors.forename: Shojiro
authors.initials: S
authors.lastname: Ochiai
authors.forename: Masahiro
authors.initials: M
authors.lastname: Wada
authors.forename: Yuzo
authors.initials: Y
authors.lastname: Daigo
authors.forename: Koichi
authors.initials: K
authors.lastname: Kita
authors.forename: Kenichi
authors.initials: K
authors.lastname: Omori
mesh_terms: D001672:Biocompatible Materials; D002113:Calcification, Physiologic; D049109:Cell Proliferation; D006801:Humans; D008422:Materials Testing / Q000379:methods; D012516:Osteosarcoma / Q000473:pathology*; D013193:Stainless Steel; D014407:Tumor Cells, Cultured
chemical_list: D001672:Biocompatible Materials; D013193:Stainless Steel