title: Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma.
authors.affiliation: University of Colorado Cancer Center, Aurora, CO, USA. jennifer.diamond@ucdenver.edu
authors.forename: Jennifer R
authors.initials: JR
authors.lastname: Diamond
authors.forename: Ravi
authors.initials: R
authors.lastname: Salgia
authors.forename: Marileila
authors.initials: M
authors.lastname: Varella-Garcia
authors.forename: Rajani
authors.initials: R
authors.lastname: Kanteti
authors.forename: Patricia M
authors.initials: PM
authors.lastname: LoRusso
authors.forename: Jeffrey W
authors.initials: JW
authors.lastname: Clark
authors.forename: Ling-Guo
authors.initials: LG
authors.lastname: Xu
authors.forename: Keith
authors.initials: K
authors.lastname: Wilner
authors.forename: S Gail
authors.initials: SG
authors.lastname: Eckhardt
authors.forename: Keith A
authors.initials: KA
authors.lastname: Ching
authors.forename: Maruja E
authors.initials: ME
authors.lastname: Lira
authors.forename: Eric F P M
authors.initials: EF
authors.lastname: Schoenmakers
authors.forename: James G
authors.initials: JG
authors.lastname: Christensen
authors.forename: D Ross
authors.initials: DR
authors.lastname: Camidge
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001706:Biopsy; D002292:Carcinoma, Renal Cell / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism / Q000556:secondary; D018450:Disease Progression; D019008:Drug Resistance, Neoplasm; D006579:Heterozygote; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007680:Kidney Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D008297:Male; D008715:Methionine; D008875:Middle Aged; D017354:Point Mutation; D019859:Proto-Oncogene Proteins c-met / Q000037:antagonists & inhibitors* / Q000235:genetics*; D011719:Pyrazines / Q000008:administration & dosage / Q000494:pharmacology*; D020794:Receptor Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors; D017422:Sequence Analysis, DNA; D013912:Threonine; D017211:Treatment Failure; D014230:Triazoles / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: C558663:2-(4-(3-quinolin-6-ylmethyl-3H-(1,2,3)triazolo(4,5-b)pyrazin-5-yl)pyrazol-1-yl)ethanol; D000970:Antineoplastic Agents; D011719:Pyrazines; D014230:Triazoles; D013912:Threonine; D008715:Methionine; D019859:Proto-Oncogene Proteins c-met; C080835:RON protein; D020794:Receptor Protein-Tyrosine Kinases