title: Allergy and inflammation: an immunological and therapeutic approach.
abstract: All organisms are protected by their immune system but occasionally this system overreacts leading to allergic and inflammatory reactions in the body. These reactions are the starting points of various diseases like asthma, eczema and urticaria etc. They involve activation of T cells, release of histamines, toxic chemicals from mast cells and eosinophils respectively. Several chemically and naturally synthesized therapeutic agents are available for the treatment of these immunological diseases. The present review provides a detailed account of mechanism of allergic and inflammatory reactions, its types and various treatment strategies with a special focus on some recent patents in this field.
authors.affiliation: Fungal Biotechnology and Invertebrate Pathology Laboratory, Department of Biological Sciences, Rani Durgawati University Jabalpur- 482001, M.P. India.
authors.forename: Shyamji
authors.initials: S
authors.lastname: Shukla
authors.forename: Harshita
authors.initials: H
authors.lastname: Shukla
authors.forename: Suneel
authors.initials: S
authors.lastname: Kumar
authors.forename: Ravindra P
authors.initials: RP
authors.lastname: Aharwal
authors.forename: Vaibhav K
authors.initials: VK
authors.lastname: Gupta
authors.forename: Sardul S
authors.initials: SS
authors.lastname: Sandhu
mesh_terms: D000818:Animals; D018926:Anti-Allergic Agents / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D015195:Drug Design; D004804:Eosinophils / Q000276:immunology; D006632:Histamine / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000188:drug therapy* / Q000276:immunology; D007249:Inflammation / Q000188:drug therapy* / Q000276:immunology; D008407:Mast Cells / Q000276:immunology; D010330:Patents as Topic; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D018926:Anti-Allergic Agents; D000893:Anti-Inflammatory Agents; D006632:Histamine