title: DDQ-induced dehydrogenation of heterocycles for C-C double bond formation: synthesis of 2-thiazoles and 2-oxazoles.
abstract: Strong as an Ox: 2-Thiazoles and 2-oxazoles are formed by oxidation of 2-thiazolines and 2-oxazolines without requiring substituents at the C4 and C5 positions. DDQ plays an important role as the oxidant in this transformation and metal is unnecessary. This general procedure shows good functional group tolerance and provides a wide variety of 2-thiazoles and 2-oxazoles in moderate to excellent yields.
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of the Ministry of Education and College of Chemistry & Materials Science, Northwest University, Xi'an Shaanxi 710069, PR China.
authors.forename: Xiangnan
authors.initials: X
authors.lastname: Li
authors.forename: Cheng
authors.initials: C
authors.lastname: Li
authors.forename: Bing
authors.initials: B
authors.lastname: Yin
authors.forename: Cong
authors.initials: C
authors.lastname: Li
authors.forename: Ping
authors.initials: P
authors.lastname: Liu
authors.forename: Jianli
authors.initials: J
authors.lastname: Li
authors.forename: Zhen
authors.initials: Z
authors.lastname: Shi
mesh_terms: D016227:Benzoquinones / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D010080:Oxazoles / Q000138:chemical synthesis / Q000737:chemistry*; D010084:Oxidation-Reduction; D013844:Thiazoles / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D016227:Benzoquinones; D010080:Oxazoles; D013844:Thiazoles; C000928:dichlorodicyanobenzoquinone; D002244:Carbon