title: Measurement of drug facilitated sexual assault agents in simulated sweat by ion mobility spectrometry.
abstract: Ion mobility spectrometry has found widespread use for the detection of explosives and illicit drugs. The technique offers rapid results with high sensitivity and little sample preparation. As such, it is well suited for field deployed screening settings. Here the response of ion mobility spectrometers for three drug-facilitated sexual assault (DFSA) agents - flunitrazepam, ketamine, and MDMA - and related metabolites has been studied in the presence of a simulated sweat. While all three DFSA agents present certain challenges for qualitative identification, IMS can provide useful information to guide the early treatment and investigation of sexual assault cases. Used as a presumptive test, the identification of DFSA agents would later require confirmatory analysis by other techniques.
authors.affiliation: Surface and Microanalysis Science Division, National Institute of Standards and Technology, 100 Bureau Dr., Gaithersburg, MD 20899, United States. leonard.demoranville@centre.edu
authors.forename: Leonard T
authors.initials: LT
authors.lastname: Demoranville
authors.forename: Jennifer R
authors.initials: JR
authors.lastname: Verkouteren
mesh_terms: D005445:Flunitrazepam / Q000032:analysis*; D053593:Forensic Toxicology; D006801:Humans; D007649:Ketamine / Q000032:analysis*; D008954:Models, Biological; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000032:analysis*; D011619:Psychotropic Drugs / Q000032:analysis*; D012680:Sensitivity and Specificity; D012742:Sex Offenses; D013054:Spectrophotometry, Atomic / Q000379:methods*; D015813:Substance Abuse Detection / Q000295:instrumentation / Q000379:methods; D013542:Sweat / Q000737:chemistry
chemical_list: D011619:Psychotropic Drugs; D005445:Flunitrazepam; D007649:Ketamine; D018817:N-Methyl-3,4-methylenedioxyamphetamine