title: Genetics of ischaemic stroke.
abstract: Recent advances in genomics and statistical computation have allowed us to begin addressing the genetic basis of stroke at a molecular level. These advances are at the cusp of making important changes to clinical practice of some monogenic forms of stroke and, in the future, are likely to revolutionise the care provided to these patients. In this review we summarise the state of knowledge in ischaemic stroke genetics particularly in the context of how a practicing clinician can best use this knowledge.
authors.affiliation: Imperial College Cerebrovascular Research Unit (ICCRU), Imperial College London, , London, UK.
authors.forename: Pankaj
authors.initials: P
authors.lastname: Sharma
authors.forename: Sunaina
authors.initials: S
authors.lastname: Yadav
authors.forename: James F
authors.initials: JF
authors.lastname: Meschia
mesh_terms: D002545:Brain Ischemia / Q000150:complications / Q000235:genetics*; D003711:Demyelinating Diseases / Q000150:complications / Q000235:genetics; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D006801:Humans; D020521:Stroke / Q000150:complications / Q000235:genetics*
keywords: CEREBROVASCULAR; CEREBROVASCULAR DISEASE; GENETICS; STROKE