title: Anticonvulsant hypersensitivity syndrome (AHS): a case report.
abstract: Anticonvulsant Hypersensitivity Syndrome (AHS) is a rare complication of common drugs used today. It is unusual in that it occurs later than most other drug reactions, about two to six weeks after initiation of the offending agent. It also has a hereditary background unlike most other drug reactions. This reaction is caused by the aromatic amines and causes hepatitis, skin rash, fever, and other systemic organ involvement can occur. The reaction is rare but often fatal, thus the observer should be acutely aware of this in the months following initiation of the agents.
authors.affiliation: Department of Internal Medicine, University of Tennessee College of Medicine, Chattanooga, USA. bradley-keel@gmail.com
authors.forename: Bradley R
authors.initials: BR
authors.lastname: Keel
authors.forename: Catherine L
authors.initials: CL
authors.lastname: Payne
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D004342:Drug Hypersensitivity / Q000150:complications / Q000209:etiology*; D005076:Exanthema / Q000139:chemically induced*; D005260:Female; D005334:Fever / Q000139:chemically induced*; D015658:HIV Infections / Q000150:complications; D006801:Humans; D010672:Phenytoin / Q000009:adverse effects*; D013577:Syndrome
chemical_list: D000927:Anticonvulsants; D010672:Phenytoin