title: Effect of heat treatments on stability of altemariol, alternariol monomethyl ether and tenuazonic acid in sunflower flour.
abstract: A study was carried out to evaluate the effect of heat treatment on the stability of alternariol (AOH), alternariol monomethyl ether (AME) and tenuazonic acid (TeA) in sunflower flour and the effectiveness of this treatment by a biological assay in rats. The concentrations of AOH and AME remained constant during heating at 100°C for up to 90 minutes while TeA concentration decreased with time to 50% after 90 minutes. The most effective treatment in reducing AOH and AME levels was heating at 121°C for 60 minutes. Histopathological evaluation in the biological assay in rats fed withAlternaria toxins showed marked atrophy and fusion of villi in the intestines and liver cell damage; these lesions were less severe in rats fed heat-treated sunflower flour in line with the reduced toxin content. However, a lower weight gain and a noticeable renal damage in rats were produced when they fed decontaminated flour.
authors.affiliation: Departamento de Microbiologίae Inmunologίa, Universidad Nacional de Rίo Cuarto, Ruta Nacional 36 km 601 (5800), Rίo Cuarto, Córdoba, Argentina.
authors.forename: M
authors.initials: M
authors.lastname: Combina
authors.forename: A
authors.initials: A
authors.lastname: Dalcero
authors.forename: E
authors.initials: E
authors.lastname: Varsavsky
authors.forename: A
authors.initials: A
authors.lastname: Torres
authors.forename: M
authors.initials: M
authors.lastname: Etcheverry
authors.forename: M
authors.initials: M
authors.lastname: Rodriguez
authors.forename: Q H
authors.initials: QH
authors.lastname: Gonzalez