title: Comparison of the effect of human milk and topical hydrocortisone 1% on diaper dermatitis.
abstract: Diaper dermatitis is one of the most common skin problems in infants and children, affecting between 7% and 35% of infants. This randomized clinical trial compared the efficacy of hydrocortisone 1% ointment with that of human breast milk in treating acute diaper dermatitis in infants ages 0 to 24 months. Infants with diaper rash were treated with either hydrocortisone 1% ointment (n = 70) or human breast milk (n = 71) for 7 days. Improvement in the rash from baseline was seen in both treatment groups on days 3 and 7; there was no significant difference in total rash scores on days 3 and 7. Treatment with human breast milk was as effective as hydrocortisone 1% ointment alone. Human breast milk is an effective and safe treatment for diaper dermatitis in infants.
authors.affiliation: Department of Midwifery, School of Nursing and Midwifery, Arak University of Medical Sciences, Arak, Iran.
authors.forename: Leila Amiri
authors.initials: LA
authors.lastname: Farahani
authors.forename: Maryam
authors.initials: M
authors.lastname: Ghobadzadeh
authors.forename: Parsa
authors.initials: P
authors.lastname: Yousefi
mesh_terms: D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D001942:Breast Feeding; D003872:Dermatitis / Q000188:drug therapy*; D003963:Diaper Rash / Q000188:drug therapy*; D006801:Humans; D006854:Hydrocortisone / Q000008:administration & dosage*; D007223:Infant; D007231:Infant, Newborn; D008895:Milk, Human; D012720:Severity of Illness Index; D012867:Skin / Q000187:drug effects; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents; D006854:Hydrocortisone