title: Genotypic sex determination in teleosts: insights from the testis-determining amhy gene.
abstract: The master sex-determining genes identified so far in fishes are clearly not conserved, as evidenced by several unrelated genes reported to play critical roles in sex determination. In this study, we reviewed the molecular process of sex determination in the Patagonian pejerrey Odontesthes hatcheri, an emerging model due to the recent discovery that a Y-chromosome linked, duplicated copy of the anti-Müllerian hormone gene, amhy plays a pivotal role in sex determination. A comparative analysis with other newly found sex-determining genes of teleost fish, DMY/dmrt1bY, sdY, amhr2, and gsdf(Y) is performed and alternative ideas are proposed to explain the mechanism involved in the rise of various types of non-homologous sex-determining genes.
authors.affiliation: Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology, Konan 4-5-7 Minato, Tokyo, Japan. Electronic address: shuheibio@yahoo.co.jp.
authors.forename: Ricardo Shohei
authors.initials: RS
authors.lastname: Hattori
authors.forename: Carlos Augusto
authors.initials: CA
authors.lastname: Strüssmann
authors.forename: Juan Ignacio
authors.initials: JI
authors.lastname: Fernandino
authors.forename: Gustavo Manuel
authors.initials: GM
authors.lastname: Somoza
mesh_terms: D000818:Animals; D005260:Female; D029941:Fish Proteins / Q000235:genetics; D005838:Genotype; D008297:Male; D019849:Sex Determination Processes / Q000235:genetics / Q000502:physiology*; D013737:Testis / Q000378:metabolism*; D014998:Y Chromosome / Q000235:genetics
chemical_list: D029941:Fish Proteins
keywords: GSD; Odontesthes hatcheri; Patagonian pejerrey; Sex-determining genes; amhy