title: Growing teratoma syndrome: Brief communication and algorithm for management.
abstract: Growing teratoma syndrome (GTS) is a rare condition among women with ovarian germ cell tumours. Women with GTS classically present during or after systemic chemotherapy with normalised tumour markers and a mass pathologically consistent with mature teratoma. Awareness of this syndrome is necessary to prevent unnecessary chemotherapy and allow optimal management. We report five cases of ovarian GTS as examples of the clinical dilemmas encountered with these women and provide recommendations and an algorithm to guide potential management.
authors.affiliation: Gynecologic Oncology Service, Department of Obstetrics and Gynecology, Walter Reed National Military Medical Center, Bethesda, MD 20889, USA.
authors.forename: Kevin
authors.initials: K
authors.lastname: Byrd
authors.forename: Michael P
authors.initials: MP
authors.lastname: Stany
authors.forename: Natasha C
authors.initials: NC
authors.lastname: Herbold
authors.forename: Charles A
authors.initials: CA
authors.lastname: Leath
authors.forename: Chad A
authors.initials: CA
authors.lastname: Hamilton
mesh_terms: D000328:Adult; D000465:Algorithms; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000628:therapy*; D013724:Teratoma / Q000175:diagnosis / Q000628:therapy*