title: Localized cutaneous fibrosing disorders.
abstract: This article acquaints the reader with disorders of the skin that might mimic systemic sclerosis but whose pathology is localized to the skin and/or has extracutaneous manifestations that are different than systemic sclerosis. These disorders include localized scleroderma (morphea), eosinophilic fasciitis, scleredema, scleromyxedema, nephrogenic systemic fibrosis, and chronic graft-versus-host disease. Particular emphasis is placed on clinical and histopathologic features that help the clinician differentiate between these disorders. Treatment options are briefly reviewed.
authors.affiliation: Division of Immunology and Rheumatology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA.
authors.forename: Aaliya
authors.initials: A
authors.lastname: Yaqub
authors.forename: Lorinda
authors.initials: L
authors.lastname: Chung
authors.forename: Kerri E
authors.initials: KE
authors.lastname: Rieger
authors.forename: David F
authors.initials: DF
authors.lastname: Fiorentino
mesh_terms: D002908:Chronic Disease; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000175:diagnosis / Q000503:physiopathology; D005208:Fasciitis / Q000175:diagnosis / Q000503:physiopathology; D006086:Graft vs Host Disease / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D033183:Interdisciplinary Communication; D054989:Nephrogenic Fibrosing Dermopathy / Q000175:diagnosis / Q000503:physiopathology; D012592:Scleredema Adultorum / Q000175:diagnosis / Q000503:physiopathology; D012594:Scleroderma, Localized / Q000175:diagnosis / Q000503:physiopathology; D012595:Scleroderma, Systemic / Q000175:diagnosis* / Q000503:physiopathology; D053718:Scleromyxedema / Q000175:diagnosis / Q000503:physiopathology; D012871:Skin Diseases / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy