title: Febrile ulceronecrotic Mucha-Habermann disease (pityriasis lichenoides et varioliformis acuta fulminans) associated with parvovirus infection.
abstract: Febrile ulceronecrotic Mucha-Habermann disease is a rare fulminant variant of pityriasis lichenoides et varioliformis acuta, characterized by a rapidly progressive course with predominant ulceronecrotic lesions associated with fever and systemic manifestations. It carries a great morbidity and is potentially fatal. The exact pathogenesis is not clear, and it has been proposed to be the result of hypersensitivity reaction to an infection. We report a patient with febrile ulceronecrotic Mucha-Habermann disease in a 12-year-old boy in whom the condition was most likely precipitated by parvovirus infection, and he showed a favorable response to a combination of prednisolone with narrow band ultraviolet B (NB-UVB) phototherapy.
authors.affiliation: Pediatric Dermatology Unit, As'ad Al-Hamad Dermatology Center, Kuwait. artinanda@hotmail.com
authors.forename: Arti
authors.initials: A
authors.lastname: Nanda
authors.forename: Faisal
authors.initials: F
authors.lastname: Alshalfan
authors.forename: Mohammad
authors.initials: M
authors.lastname: Al-Otaibi
authors.forename: Humoud
authors.initials: H
authors.lastname: Al-Sabah
authors.forename: Jihan M
authors.initials: JM
authors.lastname: Rajy
mesh_terms: D001706:Biopsy; D002648:Child; D003131:Combined Modality Therapy; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D010322:Parvoviridae Infections / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000821:virology; D017514:Pityriasis Lichenoides / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology / Q000628:therapy / Q000821:virology; D011239:Prednisolone / Q000627:therapeutic use; D012867:Skin / Q000276:immunology / Q000473:pathology; D016896:Treatment Outcome; D014467:Ultraviolet Therapy
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone