title: [Pneumonectomy: an alternative to sleeve resection in lung cancer patients?].
abstract: Lung cancer is localized in the upper lobes in more than half of the cases. The risk of tumor infiltration of centrally located structures, such as bronchi and vessels are enhanced due to the anatomic topography. Pneumonectomy competes with sleeve resection for the surgical resection of centrally located tumors. The present review deals with the question if pneumonectomy should be considered as an alternative to sleeve resection for the treatment of lung cancer. Primary pneumonectomy does not provide any advantage even in advanced nodal disease. Extended lymph node dissection is not a contraindication for sleeve resections. Local recurrence rate is lower after sleeve resections despite the same radicality for both surgical treatment options. Mortality and morbidity rates are significantly lower for sleeve resections. Sleeve resections are associated with prolonged survival and better quality of life even in elderly patients.
authors.affiliation: Klinik für Thoraxchirurgie, Dr. Horst Schmidt Klinik, Ludwig-Erhard-Str. 100, 65199 Wiesbaden, Deutschland. joachim.schirren@hsk-wiesbaden.de
authors.forename: J
authors.initials: J
authors.lastname: Schirren
authors.forename: M
authors.initials: M
authors.lastname: Schirren
authors.forename: M
authors.initials: M
authors.lastname: Passalacqua
authors.forename: S
authors.initials: S
authors.lastname: Bölükbas
mesh_terms: D000367:Age Factors; D000368:Aged; D001980:Bronchi / Q000473:pathology / Q000601:surgery; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis / Q000473:pathology; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D059351:Organ Sparing Treatments / Q000379:methods* / Q000401:mortality; D011013:Pneumonectomy / Q000379:methods* / Q000401:mortality; D011651:Pulmonary Artery / Q000473:pathology / Q000601:surgery; D011667:Pulmonary Veins / Q000473:pathology / Q000601:surgery; D011788:Quality of Life; D016019:Survival Analysis