title: China interventional stroke registry: rationale and study design.
abstract: BACKGROUND
  Angioplasty and stenting have recently become attractive options for cerebral large artery stenosis in China. However, there are limited data on safety and long-term outcomes in Chinese patients having undergone cerebral interventional procedures. To address this need, we set up a common database - the China Interventional Stroke Registry (CISR) - to describe patient characteristics, interventional images, periprocedural complications and long-term clinical outcomes and to determine how adherence to guideline-based treatments in the 'real world' works in China.
  
  
  METHODS
  Six medical centers have participated since 2004. They entered into an Internet-based database data on demographics, clinical history and angiography of patients undergoing angioplasty with/without stenting in extracranial arteries (carotid, vertebral and subclavian arteries) and/or intracranial arteries (middle cerebral artery, vertebral artery and basilar artery) in China. CISR is a research-funded project.
  
  
  RESULTS
  As of October 2012, we have already collected detailed clinical information on 1,356 patients (age: 63.6 ± 10.2 years, male: 1,084, 79.9%). The overall data quality is good. Site data quality control is supported via detailed monthly feedback reports and quarterly data monitoring meetings.
  
  
  CONCLUSIONS
  The CISR is the first and the largest registry for angioplasty with/without stents in China. The database will provide the characteristics and outcomes of patients and the situation of adherence to guideline-based treatments under 'real-world' conditions in China.
authors.affiliation: Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China. xfliu2@yahoo.com.cn
authors.forename: Xinfeng
authors.initials: X
authors.lastname: Liu
authors.forename: Yunyun
authors.initials: Y
authors.lastname: Xiong
authors.forename: Zhiming
authors.initials: Z
authors.lastname: Zhou
authors.forename: Guozhong
authors.initials: G
authors.lastname: Niu
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Guodong
authors.initials: G
authors.lastname: Xiao
authors.forename: Min
authors.initials: M
authors.lastname: Lin
authors.forename: Thomas W
authors.initials: TW
authors.lastname: Leung
authors.forename: Dezhi
authors.initials: D
authors.lastname: Liu
authors.forename: Wenhua
authors.initials: W
authors.lastname: Liu
authors.forename: Xiaobin
authors.initials: X
authors.lastname: Fan
authors.forename: Qin
authors.initials: Q
authors.lastname: Yin
authors.forename: Wusheng
authors.initials: W
authors.lastname: Zhu
authors.forename: Minmin
authors.initials: M
authors.lastname: Ma
authors.forename: Renliang
authors.initials: R
authors.lastname: Zhang
authors.forename: Gelin
authors.initials: G
authors.lastname: Xu
mesh_terms: D000368:Aged; D017130:Angioplasty / Q000009:adverse effects / Q000295:instrumentation / Q000592:standards; D002681:China / Q000453:epidemiology; D005260:Female; D019983:Guideline Adherence / Q000592:standards; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians' / Q000592:standards; D016016:Proportional Hazards Models; D011446:Prospective Studies; D012042:Registries / Q000592:standards; D012107:Research Design / Q000592:standards; D012307:Risk Factors; D015607:Stents; D020521:Stroke / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome