title: Progress in computational studies of host-pathogen interactions.
abstract: Host-pathogen interactions are important for understanding infection mechanism and developing better treatment and prevention of infectious diseases. Many computational studies on host-pathogen interactions have been published. Here, we review recent progress and results in this field and provide a systematic summary, comparison and discussion of computational studies on host-pathogen interactions, including prediction and analysis of host-pathogen protein-protein interactions; basic principles revealed from host-pathogen interactions; and database and software tools for host-pathogen interaction data collection, integration and analysis.
authors.affiliation: NUS Graduate School for Integrative Sciences & Engineering, National University of Singapore, Singapore 117456, Singapore. zhouhufeng@nus.edu.sg
authors.forename: Hufeng
authors.initials: H
authors.lastname: Zhou
authors.forename: Jingjing
authors.initials: J
authors.lastname: Jin
authors.forename: Limsoon
authors.initials: L
authors.lastname: Wong
mesh_terms: D000818:Animals; D001185:Artificial Intelligence; D003141:Communicable Diseases / Q000209:etiology; D019295:Computational Biology; D030562:Databases, Protein; D015870:Gene Expression; D054884:Host-Pathogen Interactions / Q000235:genetics / Q000502:physiology; D054298:Human Immunodeficiency Virus Proteins / Q000737:chemistry / Q000502:physiology; D006801:Humans; D008954:Models, Biological; D025941:Protein Interaction Mapping / Q000706:statistics & numerical data*; D015800:Protozoan Proteins / Q000737:chemistry / Q000502:physiology; D034622:RNA Interference; D012984:Software; D040681:Structural Homology, Protein
chemical_list: D054298:Human Immunodeficiency Virus Proteins; D015800:Protozoan Proteins