title: Glucose variability: where it is important and how to measure it.
abstract: Glucose variability predicts hypoglycemia in both type 1 and type 2 diabetes and has consistently been related to mortality in nondiabetic patients in the intensive care unit. SD and mean amplitude of glycemic excursions have historically been very popular measures of glucose variability. For reasons outlined in this counterpoint, I propose to use coefficient of variation and the mean absolute glucose change as preferred measures of glucose variability.
authors.affiliation: Academic Medical Center at the University of Amsterdam, Amsterdam, the Netherlands. j.h.devries@amc.uva.nl
authors.forename: J Hans
authors.initials: JH
authors.lastname: DeVries
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D048909:Diabetes Complications / Q000175:diagnosis; D003920:Diabetes Mellitus / Q000097:blood; D006801:Humans; D006943:Hyperglycemia / Q000097:blood; D007003:Hypoglycemia / Q000097:blood; D007362:Intensive Care Units; D019518:Postprandial Period
chemical_list: D001786:Blood Glucose