title: Heart failure biomarkers.
abstract: Biomarker testing in patients with heart failure (HF) is rapidly expanding. With high-quality research indicating its diagnostic and prognostic capabilities, biomarkers are excellent adjuncts to manage patients with HF. Their superiority lies mainly in their reflection of ongoing pathophysiological events at a cellular level. Monitoring biomarker levels has been shown to provide incremental information on the progression of disease, thus allowing to better tailor treatment and management. Several biomarkers have gained attention in the past decade and continuing research demonstrates the specificity of each biomarker to be used on its own or in combination to improve diagnostic accuracy. This review will provide an insight into the role of such biomarkers, which are widely studied in the setting of HF so as to delineate their role in diagnosing, prognosticating, and titrating HF therapy.
authors.affiliation: Department of Medicine, Capital Health Regional Medical Center-FULD, 750 Brunswick Avenue, Trenton, NJ 08638, USA. dr.rajivc@gmail.com
authors.forename: Rajiv
authors.initials: R
authors.lastname: Choudhary
authors.forename: Navaid
authors.initials: N
authors.lastname: Iqbal
authors.forename: Fatima
authors.initials: F
authors.lastname: Khusro
authors.forename: Erin
authors.initials: E
authors.lastname: Higginbotham
authors.forename: Erik
authors.initials: E
authors.lastname: Green
authors.forename: Alan
authors.initials: A
authors.lastname: Maisel
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000032:analysis*; D006333:Heart Failure / Q000175:diagnosis* / Q000378:metabolism / Q000401:mortality / Q000628:therapy; D006801:Humans; D032383:Myocytes, Cardiac / Q000378:metabolism* / Q000473:pathology; D018579:Patient Selection; D011237:Predictive Value of Tests; D011379:Prognosis
chemical_list: D015415:Biomarkers