title: Variety and complexity of fluorine-18-labelled fluoro-2-deoxy-D-glucose accumulations in the oral cavity of patients with oral cancers.
abstract: OBJECTIVE
  To elucidate the points that require attention when interpreting fluorine-18-labelled fluoro-2-deoxy-d-glucose ((18)F-FDG)/positron emission tomography (PET) images by demonstration of (18)F-FDG accumulation in various areas of the oral cavity other than primary lesions in patients with oral cancers.
  
  
  METHODS
  (18)F-FDG accumulations with a maximal standardized uptake value of over 2.5 in various areas of the oral cavity other than primary lesions were identified in 82 patients with oral cancers.
  
  
  RESULTS
  (18)F-FDG/PET-positive areas, excluding primary tumours, included the front intrinsic muscles of the tongue (89.0%), upper and lower marginal parts of the orbicularis oris muscle (64.6%), sublingual glands, palatine tonsil, pharyngeal tonsil, and lingual tonsil. In addition, some areas in the jaws also showed accumulation.
  
  
  CONCLUSIONS
  In patients with oral cancers, areas of (18)F-FDG accumulation in the oral cavity should be precisely identified and appropriately diagnosed, because accumulations can be seen in areas other than the primary tumour.
authors.affiliation: Division of Diagnostic Radiology, Kyushu Dental University, Kitakyushu 803-8580, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Kito
authors.forename: H
authors.initials: H
authors.lastname: Koga
authors.forename: M
authors.initials: M
authors.lastname: Kodama
authors.forename: M
authors.initials: M
authors.lastname: Habu
authors.forename: S
authors.initials: S
authors.lastname: Kokuryo
authors.forename: N
authors.initials: N
authors.lastname: Yamamoto
authors.forename: M
authors.initials: M
authors.lastname: Oda
authors.forename: T
authors.initials: T
authors.lastname: Nishino
authors.forename: M
authors.initials: M
authors.lastname: Zhang
authors.forename: K
authors.initials: K
authors.lastname: Matsuo
authors.forename: N
authors.initials: N
authors.lastname: Wakasugi-Sato
authors.forename: S
authors.initials: S
authors.lastname: Matsumoto-Takeda
authors.forename: Y
authors.initials: Y
authors.lastname: Seta
authors.forename: D
authors.initials: D
authors.lastname: Yoshiga
authors.forename: T
authors.initials: T
authors.lastname: Kaneuji
authors.forename: S
authors.initials: S
authors.lastname: Nogami
authors.forename: I
authors.initials: I
authors.lastname: Yoshioka
authors.forename: Y
authors.initials: Y
authors.lastname: Yamashita
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: I
authors.initials: I
authors.lastname: Miyamoto
authors.forename: C
authors.initials: C
authors.lastname: Kitamura
authors.forename: K
authors.initials: K
authors.lastname: Tominaga
authors.forename: Y
authors.initials: Y
authors.lastname: Morimoto
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000378:metabolism; D005152:Facial Muscles / Q000000981:diagnostic imaging / Q000378:metabolism; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D005887:Gingival Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D008279:Magnetic Resonance Imaging; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging / Q000378:metabolism; D008437:Maxilla / Q000000981:diagnostic imaging / Q000378:metabolism; D008875:Middle Aged; D009055:Mouth / Q000000981:diagnostic imaging* / Q000378:metabolism; D009062:Mouth Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D064847:Multimodal Imaging / Q000379:methods*; D014066:Palatine Tonsil / Q000000981:diagnostic imaging / Q000378:metabolism; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D013361:Sublingual Gland / Q000000981:diagnostic imaging / Q000378:metabolism; D014057:Tomography, X-Ray Computed; D014059:Tongue / Q000000981:diagnostic imaging / Q000378:metabolism; D014062:Tongue Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism; D055815:Young Adult
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: fluorine-18-labelled fluoro-2-deoxy-d-glucose; mimetic muscles; oral cancer; oral cavity; positron emission tomography computerized tomography; tongue