title: Nevoid follicular mucinosis: a new type of hair follicle nevus.
abstract: Follicular mucinosis represents a term for a histopathologic reaction pattern in follicular epithelium. It is a characteristic of alopecia mucinosa. However, it may also occur in a variety of unrelated conditions. Epidermal nevi are considered to be hamartomatous disorders and they can show a predominant component of non-organoid (keratinocytes) and/or organoid nevi. All the cases of epidermal nevi described with mucin deposits until now are reported as mucinous nevus or mucinous eccrine nevus; in the first type of disorder, diffuse mucin deposition is only seen in the papillary dermis, and in the second type, the mucin is found around the proliferation of eccrine structures. We believe this is the first reported case of epidermal nevus along Blaschko's lines exhibiting typical microscopic findings of mucinosis exclusively distributed inside the follicular epithelia.
authors.affiliation: Section of Dermatology, Fondazione IRCCS Cà Granda-Ospedale Maggiore Policlinico di Milano, Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. gtadinicmce@unimi.it
authors.forename: Gianluca
authors.initials: G
authors.lastname: Tadini
authors.forename: Maria P
authors.initials: MP
authors.lastname: Boldrini
authors.forename: Michela
authors.initials: M
authors.lastname: Brena
authors.forename: Lidia
authors.initials: L
authors.lastname: Pezzani
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Marchesi
authors.forename: Franco
authors.initials: F
authors.lastname: Rongioletti
mesh_terms: D002648:Child; D005260:Female; D018859:Hair Follicle / Q000378:metabolism / Q000473:pathology; D006801:Humans; D015603:Keratinocytes / Q000378:metabolism / Q000473:pathology; D000507:Mucinosis, Follicular / Q000378:metabolism / Q000473:pathology; D009077:Mucins / Q000378:metabolism; D009506:Nevus / Q000378:metabolism / Q000473:pathology; D012867:Skin / Q000378:metabolism / Q000473:pathology; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology
chemical_list: D009077:Mucins
keywords: epidermal nevus; mosaicism; nevoid follicular mucinosis