title: Glycosides from the bark of Machilus robusta.
abstract: Six new glycosidic constituents (1-6), together with 10 known analogs, have been isolated from the bark of Machilus robusta. Structures of the new compounds, including the absolute configurations, were determined by spectroscopic and chemical methods as ( - )-nectandrin B-β-d-glucopyranoside (1), ( - )-(7R,7'R,8S,8'R)-4,4'-dihydroxy-3,3'-dimethoxy-7,7'-epoxylignan-4-O-β-d-glucopyranoside (2), ( - )-(7R,7'R,8S,8'R)-4,4'-dihydroxy-3,3'-dimethoxy-7,7'-epoxylignan-4'-O-β-d-glucopyranoside (3), ( - )-(8S,8'R)-4,4'-dihydroxy-3,3',5'-trimethoxylignan-4'-O-β-d-glucopyranoside (4), ( - )-(7R,8R)-syringylglycerol-8-O-β-d-glucopyranoside (5), and ( - )-3-hydroxy-2-methyl-4-pyrone-3-O-β-d-xylopyranosyl-(1 → 6)-O-β-d-glucopyranoside (6), respectively.
authors.affiliation: State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
authors.forename: Peng-Bin
authors.initials: PB
authors.lastname: Bu
authors.forename: Yan-Ru
authors.initials: YR
authors.lastname: Li
authors.forename: Ming
authors.initials: M
authors.lastname: Jiang
authors.forename: Fang
authors.initials: F
authors.lastname: Wang
authors.forename: Xiao-Liang
authors.initials: XL
authors.lastname: Wang
authors.forename: Sheng
authors.initials: S
authors.lastname: Lin
authors.forename: Cheng-Gen
authors.initials: CG
authors.lastname: Zhu
authors.forename: Jian-Gong
authors.initials: JG
authors.lastname: Shi
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification*; D019770:Lauraceae / Q000737:chemistry*; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D004365:Drugs, Chinese Herbal; D006027:Glycosides