title: Facile preparation of ordered mesoporous silica-carbon composite nanoparticles for glycan enrichment.
abstract: Silica-carbon composite nanoparticles (NP-MCM-C) with uniform shapes and highly ordered mesoporous structures are directly prepared by using template polymers as the carbon source. And, taking advantage of the size exclusion effect of the mesopores to proteins and the specific interaction between carbon and oligosaccharides, the prepared nanoparticles are utilized to enrich N-linked glycans from complex biological samples with high selectivity and efficiency.
authors.affiliation: Key Laboratory of Separation Sciences for Analytical Chemistry, National Chromatographic R&A Center, Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS), Dalian 116023, China.
authors.forename: Hongqiang
authors.initials: H
authors.lastname: Qin
authors.forename: Zhengyan
authors.initials: Z
authors.lastname: Hu
authors.forename: Fangjun
authors.initials: F
authors.lastname: Wang
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Liang
authors.initials: L
authors.lastname: Zhao
authors.forename: Guiju
authors.initials: G
authors.lastname: Xu
authors.forename: Ren'an
authors.initials: R
authors.lastname: Wu
authors.forename: Hanfa
authors.initials: H
authors.lastname: Zou