title: Preliminary evaluation of the utility of comparing SpO2 /FiO2 and PaO2 /FiO2 ratios in dogs.
abstract: OBJECTIVE
  To determine whether the ratio of pulse oximetry saturation/fraction of inspired oxygen (SpO2 /FiO2 , [SF]) correlates with the ratio of partial pressure of oxygen in arterial blood/FiO2 (PaO2 /FiO2 , [PF]) in dogs.
  
  
  METHODS
  Prospective, observational pilot study.
  
  
  METHODS
  Urban tertiary veterinary referral center.
  
  
  METHODS
  Thirty-eight client-owned dogs requiring assessment of oxygenation.
  
  
  METHODS
  None.
  
  
  RESULTS
  Arterial blood gas analysis with co-oximetry was performed on samples obtained from the dorsal pedal artery. Median SpO2 was 91.5% (range 80-97%) and median PaO2 was 70.1 mmHg (range 44.5-103.8 mmHg). Hypoventilation was uncommon and venous admixture was the predominant cause of hypoxemia in this population. Median SF was 435.7 (range 381.0-461.9) and median PF was 334.0 (range 211.9-494.3). Nine dogs (23.6%) had PF <300; no dogs had PF below 200. SF and PF were correlated (ρ = 0.618, P < 0.01).
  
  
  CONCLUSIONS
  SF and PF in dogs spontaneously breathing room air have good correlation, suggesting that SF may be a useful, noninvasive surrogate for PF when assessing oxygenation in canine patients. Further studies are warranted to confirm and validate this relationship in spontaneously breathing and mechanically ventilated dogs on varying levels of FiO2 and to assess the ability of SF to predict outcome.
authors.affiliation: Departments of Emergency and Critical Care, The Animal Medical Center, New York, NY 10065, USA. janine.calabro@gmail.com
authors.forename: Janine M
authors.initials: JM
authors.lastname: Calabro
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Prittie
authors.forename: Douglas A
authors.initials: DA
authors.lastname: Palma
mesh_terms: D000818:Animals; D004285:Dogs; D005260:Female; D008297:Male; D010092:Oximetry / Q000662:veterinary*; D010100:Oxygen / Q000097:blood*; D010102:Oxygen Inhalation Therapy / Q000662:veterinary; D010313:Partial Pressure; D010865:Pilot Projects
chemical_list: D010100:Oxygen