title: The long and short of microRNA.
abstract: MicroRNAs (miRNAs) are versatile regulators of gene expression in higher eukaryotes. In order to silence many different mRNAs in a precise manner, miRNA stability and efficacy is controlled by highly developed regulatory pathways and fine-tuning mechanisms both affecting miRNA processing and altering mature miRNA target specificity.
authors.affiliation: Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
authors.forename: Luke A
authors.initials: LA
authors.lastname: Yates
authors.forename: Chris J
authors.initials: CJ
authors.lastname: Norbury
authors.forename: Robert J C
authors.initials: RJ
authors.lastname: Gilbert
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D006801:Humans; D035683:MicroRNAs / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D012323:RNA Processing, Post-Transcriptional; D043244:Ribonuclease III / Q000378:metabolism
chemical_list: D035683:MicroRNAs; D043244:Ribonuclease III