title: Complex etiology and pathology of mycotoxic nephropathy in South African pigs.
abstract: Spontaneous nephropathy in pigs seen in South Africa was found to have multi-mycotoxic etiology involving several mycotoxins such as ochratoxin A (OTA), penicillic acid (PA) and fumonisin B1 (FB1) in addition to a not yet identified mycotoxin. Contamination levels of OTA were comparatively low (67-75 μg/kg) in contrast to high contamination levels of FB1 (5,289-5,021 μg/kg) and PA (149-251 μg/kg). A heavy contamination with Gibberella fujikuroi var. moniliformis and Penicillium aurantiogriseum complex (mainly P. polonicum) was observed in the fed forages in contrast to the light contamination with Aspergillus ochraceus, P. verrucosum and P. citrinum. The pathomorphological picture of this nephropathy was found to differ from the classical description of mycotoxic porcine nephropathy as originally made in Scandinavia by the extensive vascular changes.
authors.affiliation: Department of General and Clinical Pathology, Faculty of Veterinary Medicine, Trakia University, Students Campus, 6000, Stara Zagora, Bulgaria, stoev@uni-sz.bg.
authors.forename: Stoycho D
authors.initials: SD
authors.lastname: Stoev
authors.forename: Stefan
authors.initials: S
authors.lastname: Denev
authors.forename: Mike F
authors.initials: MF
authors.lastname: Dutton
authors.forename: Patrick B
authors.initials: PB
authors.lastname: Njobeh
authors.forename: Joseph S
authors.initials: JS
authors.lastname: Mosonik
authors.forename: Paul A
authors.initials: PA
authors.lastname: Steenkamp
authors.forename: Iordan
authors.initials: I
authors.lastname: Petkov