title: False Positive FDG PET/CT Resulting from Fibrous Dysplasia of the Bone in the Work-Up of a Patient with Bladder Cancer: Case Report and Review of the Literature.
abstract: Fibrous dysplasia of the bone (FDB) is a common, genetic, developmental disorder with a benign course. FDB can be seen anywhere throughout the skeleton. It is usually asymptomatic and found incidentally on imaging studies that are performed for other purposes. Although whole body 18 F-flourodeoxyglucose PET/CT (FDG PET/CT) is widely used in tumor imaging, infections and benign pathologies like FDB may cause false positive results. Herein we report the case of a 48-year-old FDB patient with transitional cell carcinoma of the urinary bladder. Restaging FDG PET/CT showed multiple mild to moderate hypermetabolic bone lesions which were initially misinterpreted as bone metastases. In this case report, we aimed to guide physicians in evaluating bone lesions in cancer patients with FDB in the light of the literature.
authors.affiliation: Department of Nuclear Medicine, Marmara University School of Medicine, Istanbul, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Aras
authors.forename: Tunc
authors.initials: T
authors.lastname: Ones
authors.forename: Faysal
authors.initials: F
authors.lastname: Dane
authors.forename: Omid
authors.initials: O
authors.lastname: Nosheri
authors.forename: Sabahat
authors.initials: S
authors.lastname: Inanir
authors.forename: Tanju Yusuf
authors.initials: TY
authors.lastname: Erdil
authors.forename: Halil Turgut
authors.initials: HT
authors.lastname: Turoglu
keywords: 18F-Flourodeoxyglucose, PET, CT; Bone and Bones; Fibrous Dysplasia, Polyostotic