title: Structure-based fragment screening is demonstrated to be a practical lead discovery method for a representative G-protein-coupled receptor.
authors.affiliation: Cambridge Laboratories, Pfizer Worldwide Research and Development , 620 Memorial Drive, Cambridge, Massachusetts 02139, United States. Benjamin.stevens@pfizer.com
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Stevens
mesh_terms: D004353:Drug Evaluation, Preclinical / Q000379:methods*; D008024:Ligands; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism*
chemical_list: D008024:Ligands; D043562:Receptors, G-Protein-Coupled