title: Plasmon resonance scattering spectroscopy at the single-nanoparticle level: real-time monitoring of a click reaction.
abstract: A method based on plasmon resonance Rayleigh scattering (PRRS) spectroscopy and dark-field microscopy (DFM) was established for the real-time monitoring of a click reaction at the single-nanoparticle level. Click reactions on the surface of single gold nanoparticles (GNPs) result in interparticle coupling, which leads to a red-shift of the λmax (Δλmax =43 nm) in the PRRS spectra and a color change of the single gold nanoparticles in DFM (from green to orange).
authors.affiliation: State Key Laboratory of Bioreactor Engineering, & Department of Chemistry, East China University of Science and Technology, Shanghai, 200237, PR China.
authors.forename: Lei
authors.initials: L
authors.lastname: Shi
authors.forename: Chao
authors.initials: C
authors.lastname: Jing
authors.forename: Wei
authors.initials: W
authors.lastname: Ma
authors.forename: Da-Wei
authors.initials: DW
authors.lastname: Li
authors.forename: Jonathan E
authors.initials: JE
authors.lastname: Halls
authors.forename: Frank
authors.initials: F
authors.lastname: Marken
authors.forename: Yi-Tao
authors.initials: YT
authors.lastname: Long
mesh_terms: D057930:Click Chemistry; D053758:Nanoparticles / Q000737:chemistry*; D013057:Spectrum Analysis; D020349:Surface Plasmon Resonance / Q000379:methods*