title: Ischemic stroke predicts myocardial injury after carotid endarterectomy for symptomatic severe carotid artery stenosis.
abstract: Myocardial injury following carotid endarterectomy (CEA) is a common cause of morbidity and mortality, and its risk varies depending on the severity and extent of disease. However, when patients with sympotomatic severe carotid stenosis undergo CEA, the frequency and potential predictors of myocardial injury remain unknown. A total of 40 patients (32 men and 8 women) who underwent successful standard CEA were observed. Cardiac troponin I (cTnI) concentrations were assessed before surgery and on postoperative days 1, 2, and 3 in all patients. Myocardial injury was defined as the peak cTnI concentration > 0.04 ng/mL. In all, 42.5% patients had postoperative myocardial injury. Previous ischemic stroke and abnormal ST-segment changes were the preoperative predictors of myocardial injury after CEA, with odds ratios of 4.1 (95% confidence interval, 1.1-16.1; P = .04) and 5.9 (95% confidence interval, 1.3-27.7; P = .04), respectively. Sympotomatic patients with those conditions should receive more attention to myocardial injury, when presented for CEA.
authors.affiliation: 1Department of Anesthesiology, Xuanwu Hospital of Capital Medical University, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Feng
authors.forename: Tian-Long
authors.initials: TL
authors.lastname: Wang
authors.forename: Bing
authors.initials: B
authors.lastname: Cai
mesh_terms: D000368:Aged; D050197:Atherosclerosis / Q000473:pathology; D016893:Carotid Stenosis / Q000473:pathology / Q000601:surgery*; D016894:Endarterectomy, Carotid / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000209:etiology* / Q000473:pathology; D012307:Risk Factors; D020521:Stroke / Q000473:pathology*
keywords: atherosclerosis; cardiology; stroke; vascular and endovascular surgery