title: Diet and genetics: Trp-ing over food sensitivity.
abstract: Laboratory-reared Caenorhabditis elegans eat Escherichia coli. A new study demonstrates a strong diet-gene interaction: worms with reduced nhr-114 activity are fertile when fed E. coli K-12 strains but are sterile on E. coli B. Surprisingly, tryptophan supplementation of E. coli B restores worm fertility.
authors.affiliation: New York University School of Medicine, Skirball Institute for Biomolecular Medicine, 540 First Avenue, New York, NY 10016, USA. jane.hubbard@med.nyu.edu
authors.forename: E Jane Albert
authors.initials: EJ
authors.lastname: Hubbard
mesh_terms: D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D017173:Caenorhabditis elegans / Q000502:physiology*; D004032:Diet; D041981:Gastrointestinal Tract / Q000382:microbiology*; D005854:Germ Cells / Q000166:cytology*; D051557:Hepatocyte Nuclear Factor 4 / Q000378:metabolism*; D013234:Stem Cells / Q000166:cytology*
chemical_list: D051557:Hepatocyte Nuclear Factor 4