title: Malignant transformation in the course of a dentigerous cyst: a problem for a clinician and a pathologist. Considerations based on a case report.
abstract: Primary intraosseous squamous cell carcinoma (PIOSCC) is a rarely reported neoplasm resulting from malignant transformation of a dentigerous cyst of the mandible or maxilla. Until 2010, only 116 cases had been described. The diagnosis of PIOSCC is difficult because of non-specific symptoms. A case of a 66-year-old patient with PIOSCC arising from a dentigerous cyst of the mandible is presented. Both pathologists and clinicians should be aware of the probability of malignant transformation of dentigerous cysts during the two-stage treatment. The patient should be subject to regular clinical and radiographic examination.
authors.affiliation: Department of Oral Surgery, Jagiellonian University Medical College, Kraków, Poland. agnieszka.zapala-pospiech@uj.edu.pl
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Zapała-Pośpiech
authors.forename: Grażyna
authors.initials: G
authors.lastname: Wyszyńska-Pawelec
authors.forename: Dariusz
authors.initials: D
authors.lastname: Adamek
authors.forename: Romana
authors.initials: R
authors.lastname: Tomaszewska
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Zaleska
authors.forename: Jan
authors.initials: J
authors.lastname: Zapała
mesh_terms: D000368:Aged; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D002471:Cell Transformation, Neoplastic; D003803:Dentigerous Cyst / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008334:Mandible / Q000473:pathology; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D008437:Maxilla / Q000473:pathology; D011044:Poland; D011862:Radiography, Panoramic