title: Ruthenium-catalyzed direct C-H amidation of arenes including weakly coordinating aromatic ketones.
abstract: C-H activation: The ruthenium-catalyzed direct sp(2) C-H amidation of arenes by using sulfonyl azides as the amino source is presented (see scheme). A wide range of substrates were readily amidated including arenes bearing weakly coordinating groups. Synthetic utility of the thus obtained products was demonstrated in the preparation of biologically active heterocycles.
authors.affiliation: Center for Catalytic Hydrocarbon Funtionalizations (IBS) and Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Korea.
authors.forename: Jiyu
authors.initials: J
authors.lastname: Kim
authors.forename: Jinwoo
authors.initials: J
authors.lastname: Kim
authors.forename: Sukbok
authors.initials: S
authors.lastname: Chang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001386:Azides; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D006860:Hydrogen Bonding; D007659:Ketones / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*
chemical_list: D000475:Alkenes; D001386:Azides; D006571:Heterocyclic Compounds; D007659:Ketones; D012428:Ruthenium