title: Multicomponent multicatalyst reactions (MC)2R: one-pot synthesis of 3,4-dihydroquinolinones.
abstract: A Rh/Pd/Cu catalyst system led to an efficient synthesis of dihydroquinolinones in one-pot, two operations. The reaction features the first triple metal-catalyzed transformations in one reaction vessel, without any intermediate workup. The conjugate-addition/amidation/amidation reaction sequence is highly modular, divergent, and practical.
authors.affiliation: Davenport Research Laboratories, Department of Chemistry, University of Toronto, 80 St George Street, Toronto, Ontario M5S 3H6, Canada.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Sonaglia
authors.forename: Jason
authors.initials: J
authors.lastname: Stacey
authors.forename: Mark
authors.initials: M
authors.lastname: Lautens
mesh_terms: D002384:Catalysis; D008670:Metals / Q000737:chemistry*; D015394:Molecular Structure; D015363:Quinolones / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D008670:Metals; D015363:Quinolones