title: [Comparison of two different methods to detect HIV antibodies].
abstract: OBJECTIVE
  Evaluated the chemiluminescence and enzyme-linked immunosorbent assay (ELISA) to detect HIV antibodies, and compared the results, to provide a reference for the selection and clinical application of HIV screening.
  
  
  METHODS
  3000 cases of our hospital patients were measured by enzyme-linked immunosorbent assay and chemiluminescence immunoassay, using comfirmming experimental results as gold standards. Comparing sensitivity, specificity and other Indicators.
  
  
  RESULTS
  In the diagnosis of HIV infection, enzyme-linked immunosorbent assay and chemiluminescence immunoassay had no significant difference. The positive rate of enzyme-linked immunosorbent assay was 0.93%, while the sensitivity and specificity were 89.66%, 99.93%, the positive rate of chemiluminescence immunoassay was 1.03%, while the sensitivity and specificity were 100%, 99.93%, respectively.
  
  
  CONCLUSIONS
  Both methods are suitable for screening of HIV, having high specificity, and chemiluminescence has greater sensitivity than ELISA.
authors.affiliation: Center of Clinical Laboratory, The No. 302 Hospital of the PLA, Beijing, China.
authors.forename: Jing-Xia
authors.initials: JX
authors.lastname: Guo
authors.forename: Jun
authors.initials: J
authors.lastname: Xu
authors.forename: Lin
authors.initials: L
authors.lastname: Chen
authors.forename: Jia
authors.initials: J
authors.lastname: Liu
authors.forename: Jing
authors.initials: J
authors.lastname: Zhao
authors.forename: Yong-Ji
authors.initials: YJ
authors.lastname: Song
authors.forename: Ai-Xia
authors.initials: AX
authors.lastname: Liu
authors.forename: Bo-An
authors.initials: BA
authors.lastname: Li
authors.forename: Yuan-Li
authors.initials: YL
authors.lastname: Mao
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods*; D005260:Female; D015483:HIV Antibodies / Q000097:blood*; D015658:HIV Infections / Q000175:diagnosis / Q000276:immunology*; D006801:Humans; D008163:Luminescent Measurements / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D055815:Young Adult
chemical_list: D015483:HIV Antibodies