title: Comment on "In monkeys making value-based decisions, LIP neurons encode cue salience and not action value".
abstract: Leathers and Olson (Reports, 5 October 2012, p. 132) draw the strong conclusion that neurons in the monkey lateral intraparietal (LIP) cortical area encode only cue salience, and not action value, during value-based decision-making. Although their findings regarding cue salience are interesting, their broader conclusions are problematic because (i) their primary conclusion is based on responses observed during a brief interval at the beginning of behavioral trials but is extended to all subsequent temporal epochs and (ii) the authors failed to replicate basic hallmarks of LIP physiology observed in those subsequent temporal epochs by many laboratories.
authors.affiliation: Department of Neurobiology and Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
authors.forename: William T
authors.initials: WT
authors.lastname: Newsome
authors.forename: Paul W
authors.initials: PW
authors.lastname: Glimcher
authors.forename: Jacqueline
authors.initials: J
authors.lastname: Gottlieb
authors.forename: Daeyeol
authors.initials: D
authors.lastname: Lee
authors.forename: Michael L
authors.initials: ML
authors.lastname: Platt
mesh_terms: D000818:Animals; D003463:Cues; D003657:Decision Making / Q000502:physiology*; D008297:Male; D009042:Motivation / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D012438:Saccades / Q000502:physiology*; D012945:Social Values