title: Personalized medicine in the care of the child with congenital heart disease: discovery to application.
abstract: On October 27-28, 2012, the SickKids Labatt Family Heart Centre and the Heart Centre Biobank Registry hosted the second international GenomeHeart symposium in Toronto, Ontario. The symposium featured experts in cardiology, developmental biology, pharmacology, genomics, bioinformatics, stem cell biology, biobanking, and ethics. The theme of this year's symposium was the application of emerging technologies in genomics, proteomics, transcriptomics, and bioinformatics to diagnostics and therapeutics of the child with heart disease. Social, ethical, and economic issues were also discussed in the context of clinical translation. We highlight some of the themes that emerged from this exciting 2-day event.
authors.affiliation: Division of Pediatric Cardiology, Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.
authors.forename: Tina
authors.initials: T
authors.lastname: Binesh Marvasti
authors.forename: Lisa C A
authors.initials: LC
authors.lastname: D'Alessandro
authors.forename: Dorin
authors.initials: D
authors.lastname: Manase
authors.forename: Tanya
authors.initials: T
authors.lastname: Papaz
authors.forename: Seema
authors.initials: S
authors.lastname: Mital
mesh_terms: D002309:Cardiology / Q000191:economics / Q000941:ethics / Q000639:trends; D004059:Diffusion of Innovation; D005544:Forecasting; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D023281:Genomics; D017048:Health Care Costs; D006330:Heart Defects, Congenital / Q000175:diagnosis* / Q000191:economics / Q000235:genetics / Q000628:therapy*; D006801:Humans; D018579:Patient Selection; D010372:Pediatrics / Q000191:economics / Q000941:ethics / Q000639:trends; D010597:Pharmacogenetics; D057285:Precision Medicine / Q000191:economics / Q000941:ethics / Q000639:trends; D011237:Predictive Value of Tests; D012307:Risk Factors