title: Periocular triamcinolone acetonide injections for control of intraocular inflammation associated with uveitis.
abstract: OBJECTIVE
  To describe the effectiveness of periocular corticosteroid injections for the control of intraocular inflammation associated with noninfectious uveitis.
  
  
  METHODS
  A total of 81 patients (109 eyes) who received a periocular injection were evaluated for active inflammation, visual acuity, intraocular pressure, degree of intraocular inflammation, and the presence of ocular complications, including macular edema.
  
  
  RESULTS
  Of all eyes, 36% (95%CI: 25%, 45%) demonstrated clinical resolution of inflammation at the 1-month visit after first injection, and 48% (95%CI: 37%, 59%) at 3 months. For multiple injections, 50% (95%CI: 28%, 72%) demonstrated resolution of inflammation at 1 month after the last injection, and 41% (95%CI: 20%, 63%) resolution of inflammation at 3 months after the last injection. Of the 49 eyes that initially responded, the estimated median time to recurrence was 7.6 months.
  
  
  CONCLUSIONS
  Approximately half of the treated eyes had resolution of intraocular inflammation at 3 months after corticosteroid injection.
authors.affiliation: Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
authors.forename: Sherveen S
authors.initials: SS
authors.lastname: Salek
authors.forename: Henry A
authors.initials: HA
authors.lastname: Leder
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Butler
authors.forename: Theresa J
authors.initials: TJ
authors.lastname: Gan
authors.forename: James P
authors.initials: JP
authors.lastname: Dunn
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Thorne
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D056965:Injections, Intraocular; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*; D014605:Uveitis / Q000188:drug therapy* / Q000503:physiopathology; D014792:Visual Acuity; D055815:Young Adult
chemical_list: D005938:Glucocorticoids; D014222:Triamcinolone Acetonide