title: RSVSim: an R/Bioconductor package for the simulation of structural variations.
abstract: RSVSim is a tool for the simulation of deletions, insertions, inversions, tandem duplications and translocations of various sizes in any genome available as FASTA-file or data package in R. The structural variations can be generated randomly, based on user-supplied genomic coordinates or associated to various kinds of repeats. The package further comprises functions to estimate the distribution of structural variation sizes from real datasets.
  
  
  BACKGROUND
  RSVSim is implemented in R and available at http://www.bioconductor.org. A vignette with detailed descriptions of the functions and examples is included.
authors.affiliation: Institute of Medical Informatics, University of Münster, Münster. christoph.bartenhagen@uni-muenster.de
authors.forename: Christoph
authors.initials: C
authors.lastname: Bartenhagen
authors.forename: Martin
authors.initials: M
authors.lastname: Dugas
mesh_terms: D056905:Chromosome Breakpoints; D003198:Computer Simulation; D016678:Genome; D056914:Genomic Structural Variation; D023281:Genomics / Q000379:methods; D012984:Software