title: Total synthesis of the tubulin inhibitor WF-1360F based on macrocycle formation through ring-closing alkyne metathesis.
authors.affiliation: Swiss Federal Institute of Technology Zürich, Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, HCI H405, Wolfgang-Pauli-Strasse 10, 8093 Zürich, Switzerland.
authors.forename: Christian M
authors.initials: CM
authors.lastname: Neuhaus
authors.forename: Marc
authors.initials: M
authors.lastname: Liniger
authors.forename: Martin
authors.initials: M
authors.lastname: Stieger
authors.forename: Karl-Heinz
authors.initials: KH
authors.lastname: Altmann
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D047028:Macrocyclic Compounds / Q000737:chemistry*; D018942:Macrolides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D050257:Tubulin Modulators / Q000138:chemical synthesis* / Q000737:chemistry; D014753:Vinyl Compounds / Q000737:chemistry
chemical_list: D000480:Alkynes; D047028:Macrocyclic Compounds; D018942:Macrolides; D050257:Tubulin Modulators; D014753:Vinyl Compounds; C569210:vinyl iodide; C041443:rhizoxin