title: Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part II.
abstract: In part II of this review, we describe the epidemiology and clinical consequences of vascular disease in patients with diabetes, and discuss the efficacy of risk factor modification and antiplatelet treatment. Specifically, evidence-based cardiovascular therapies are discussed through novel clinical insights on management of hyperglycaemia, hypertension, dyslipidaemia as well as platelet dysfunction. Recent trends in the incidence and outcomes of vascular disease in diabetes suggest that timely and effective implementation of therapies is making a favourable impact.
authors.affiliation: Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. jbeckman@partners.org
authors.forename: Joshua A
authors.initials: JA
authors.lastname: Beckman
authors.forename: Francesco
authors.initials: F
authors.lastname: Paneni
authors.forename: Francesco
authors.initials: F
authors.lastname: Cosentino
authors.forename: Mark A
authors.initials: MA
authors.lastname: Creager
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D050197:Atherosclerosis / Q000188:drug therapy / Q000453:epidemiology; D003327:Coronary Disease / Q000188:drug therapy / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy* / Q000453:epidemiology; D003925:Diabetic Angiopathies / Q000188:drug therapy* / Q000453:epidemiology; D050171:Dyslipidemias / Q000517:prevention & control; D014943:Global Health; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use; D006943:Hyperglycemia / Q000517:prevention & control; D006973:Hypertension / Q000517:prevention & control; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D015425:Myocardial Reperfusion / Q000379:methods; D058729:Peripheral Arterial Disease / Q000188:drug therapy / Q000453:epidemiology; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D015995:Prevalence; D040242:Risk Reduction Behavior; D020521:Stroke / Q000188:drug therapy / Q000453:epidemiology
chemical_list: D000959:Antihypertensive Agents; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D007004:Hypoglycemic Agents; D010975:Platelet Aggregation Inhibitors
keywords: Diabetes; Medical therapy; Vascular disease