title: Palladium-catalyzed olefination and arylation of 2-substituted 1,2,3-triazole N-oxides.
abstract: Two highly efficient protocols for the regioselective synthesis of 2-substituted 4-alkenyl- and 4-aryl-1,2,3-triazoles by the palladium-catalyzed C-H functionalization of 1,2,3-triazole N-oxides are reported. A possible pathway of direct alkenylation with 1-octene and vinyl acetate is discussed.
authors.affiliation: Department of Chemistry, Tongji University , Siping Road 1239, Shanghai 200092, P. R. China, and Key Laboratory of Yangtze River Water Environment , Ministry of Education, Siping Road 1239, Shanghai 200092, P. R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Yahui
authors.initials: Y
authors.lastname: Li
authors.forename: Bo
authors.initials: B
authors.lastname: Xu
authors.forename: Chunxiang
authors.initials: C
authors.lastname: Kuang
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000478:Alkylation; D002384:Catalysis; D003497:Cyclic N-Oxides / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*; D013237:Stereoisomerism; D014230:Triazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000475:Alkenes; D003497:Cyclic N-Oxides; D014230:Triazoles; D010165:Palladium