title: Biomolecular release triggered by glucose input--bioelectronic coupling of sensing and actuating systems.
abstract: A drug-mimicking release process was triggered by a glucose signal resulting in the formation of a negative potential on an electrode modified with PQQ-dependent glucose dehydrogenase. This electrode was coupled with another electrode coated with an Fe(+3)-crosslinked alginate polymer film, which was dissolved upon formation of the negative potential releasing entrapped species.
authors.affiliation: Department of Chemistry and Biomolecular Science, Clarkson University, Potsdam, NY 13699, USA.
authors.forename: Shay
authors.initials: S
authors.lastname: Mailloux
authors.forename: Jan
authors.initials: J
authors.lastname: Halámek
authors.forename: Lenka
authors.initials: L
authors.lastname: Halámková
authors.forename: Alexander
authors.initials: A
authors.lastname: Tokarev
authors.forename: Sergiy
authors.initials: S
authors.lastname: Minko
authors.forename: Evgeny
authors.initials: E
authors.lastname: Katz
mesh_terms: D000464:Alginates / Q000737:chemistry*; D015374:Biosensing Techniques; D055664:Electrochemical Techniques; D004566:Electrodes; D005947:Glucose / Q000737:chemistry*; D042843:Glucose 1-Dehydrogenase / Q000737:chemistry; D006046:Gold / Q000737:chemistry; D006735:Horseradish Peroxidase / Q000737:chemistry; D007501:Iron / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry; D045542:PQQ Cofactor / Q000737:chemistry
chemical_list: D000464:Alginates; D045542:PQQ Cofactor; D006046:Gold; D007501:Iron; D042843:Glucose 1-Dehydrogenase; D006735:Horseradish Peroxidase; D005947:Glucose