title: Induced-membrane femur reconstruction after resection of bone malignancies: three cases of massive graft resorption in children.
abstract: Bone reconstruction after surgical resection of bone malignancies in children remains a difficult challenge. Induced-membrane reconstruction as described by Masquelet et al. was originally reported in traumatic or septic bone defects and is now adapted to this field. We report here three cases of massive femoral graft resorption requiring surgical revision in two boys aged 3 and 6 years and a 9-year-old girl. Hypotheses include the long delay between the two stages, nature of the bone graft, high varus loads specific to this location, and lack of stability of the fixation. This technique has recently provided promising preliminary results when applied to the field of bone tumours. However, reconstruction of the femur seems to be specifically associated with a risk of graft resorption. Identification of the origin of this major complication is needed to amend the technique or its indications.
authors.affiliation: Department of orthopaedic, trauma and plastic reconstructive surgery, Children Hospital, 330, avenue de Grande-Bretagne, BP 3119, 31059 Toulouse cedex 3, France. faccadbled@wanadoo.fr
authors.forename: F
authors.initials: F
authors.lastname: Accadbled
authors.forename: P
authors.initials: P
authors.lastname: Mazeau
authors.forename: F
authors.initials: F
authors.lastname: Chotel
authors.forename: J
authors.initials: J
authors.lastname: Cottalorda
authors.forename: J
authors.initials: J
authors.lastname: Sales de Gauzy
authors.forename: R
authors.initials: R
authors.lastname: Kohler
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D016025:Bone Transplantation / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005269:Femur / Q000601:surgery*; D006801:Humans; D008297:Male; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000601:surgery*; D011859:Radiography; D019651:Plastic Surgery Procedures / Q000379:methods*; D012086:Reoperation; D013977:Tibia / Q000637:transplantation*