title: [Relationship between body mass index and volume ratio of brain gray matter in patients with first-episode schizophrenia].
abstract: OBJECTIVE
  To analyze the relationship between psychotic symptoms and body mass index (BMI) and brain mass index in patients with first-episode schizophrenia.
  
  
  METHODS
  We identified 97 patients with first-episode and drug-free schizophrenia and compared their BMI and scare MRI results with 97 healthy participants.
  
  
  RESULTS
  There were no statistically significant differences in BMI, volume of white matter and volume of grey matter between the patients with schizophrenia and healthy participants. BMI was positively correlated with age and negatively correlated with gray matter volume and the ratio of gray matter volume in the healthy participants. No such correlations were found in the patients with schizophrenia. BMI were not correlated with the total score of PANSS, nor with the factor score of PANSS.
  
  
  CONCLUSIONS
  BMI is positive correlated with age, but negatively correlated with gray matter volume and the ratio of gray matter volume in healthy adult. But such correlations disappear in patients with schizophrenia. BMI is not associated with the seriousness of psychotic symptoms.
authors.affiliation: Mental Health Center, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Deng
authors.forename: Zong-Ling
authors.initials: ZL
authors.lastname: He
authors.forename: Ming-Li
authors.initials: ML
authors.lastname: Li
authors.forename: Ming-Min
authors.initials: MM
authors.lastname: Huang
authors.forename: Tao
authors.initials: T
authors.lastname: Li
authors.forename: Hong
authors.initials: H
authors.lastname: Deng
mesh_terms: D000328:Adult; D015992:Body Mass Index; D066128:Gray Matter / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D012559:Schizophrenia / Q000503:physiopathology*