title: Allergy and sleep-disordered breathing.
abstract: OBJECTIVE
  An inconsistent link between sleep-disordered breathing (SDB) and allergic rhinitis has been reported in the literature for decades. This review attempts to highlight some of the recent epidemiological studies purporting and refuting this connection, discuss possible mechanisms for this relationship and discuss how treatment of allergic rhinitis can help ameliorate SDB.
  
  
  RESULTS
  Recently, a large systematic review that included 18 studies and 27 000 individuals of the association between allergic rhinitis and SDB in children was published supporting a correlation between SDB and allergic rhinitis.
  
  
  CONCLUSIONS
  Although the evidence generally supports a connection between SDB and allergic rhinitis, this connection is not definitive and the mechanism linking these two diseases remains poorly understood. In addition to epidemiological studies, several small studies have demonstrated an improvement in SDB upon treatment of allergic rhinitis; however, large studies using objective measures to quantify SDB and allergic rhinitis are needed.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of North Carolina, Chapel Hill, North Carolina, USA.
authors.forename: Adam J
authors.initials: AJ
authors.lastname: Kimple
authors.forename: Stacey L
authors.initials: SL
authors.lastname: Ishman
mesh_terms: D000328:Adult; D002648:Child; D006801:Humans; D012221:Rhinitis, Allergic, Perennial / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology; D012891:Sleep Apnea Syndromes / Q000209:etiology*