title: Nickel-catalyzed Suzuki-Miyaura coupling of heteroaryl ethers with arylboronic acids.
abstract: Nickel-catalyzed Suzuki-Miyaura coupling of heteroaryl ethers with arylboronic acids was described. Selective activation of the phenol C-O bonds was achieved by converting them into the corresponding aryl 2,4-dimethoxy-1,3,5-triazine-6-yl ethers, in which aryl C-O bond could be selectively cleaved with inexpensive, air-stable NiCl2(dppf) as a catalyst. Coupling of these readily accessible heteroaryl ethers proved tolerant of extensive functional groups.
authors.affiliation: State Key Laboratory and Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China.
authors.forename: Xiao-Jian
authors.initials: XJ
authors.lastname: Li
authors.forename: Jin-Ling
authors.initials: JL
authors.lastname: Zhang
authors.forename: Yu
authors.initials: Y
authors.lastname: Geng
authors.forename: Zhong
authors.initials: Z
authors.lastname: Jin
mesh_terms: D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D004987:Ethers / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D009942:Organometallic Compounds / Q000737:chemistry*
chemical_list: D001555:Benzene Derivatives; D001897:Boronic Acids; D004987:Ethers; D009942:Organometallic Compounds; D009532:Nickel