title: The use of propofol to prevent fetal deceleration during electroconvulsive therapy treatment.
abstract: Electroconvulsive therapy has been demonstrated to be relatively safe during pregnancy for both the mother and the fetus. One risk to the fetus is cardiac deceleration during the grand mal seizure. We present a case of a young woman in her second trimester of pregnancy with bipolar depression. She had a prolonged seizure on her second electroconvulsive therapy treatment, which led to transient fetal bradycardia that self-corrected as preparations were underway for an emergency cesarean delivery. A change of her anesthetic agent from methohexital to propofol attenuated the seizure duration resulting in the elimination of further events of fetal cardiac deceleration and a successful outcome for both mother and fetus.
authors.affiliation: From the Yale University, New Haven, CT.
authors.forename: Sarah Jane
authors.initials: SJ
authors.lastname: De Asis
authors.forename: Lars
authors.initials: L
authors.lastname: Helgeson
authors.forename: Robert
authors.initials: R
authors.lastname: Ostroff
mesh_terms: D018686:Anesthetics, Intravenous / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000628:therapy*; D001919:Bradycardia / Q000517:prevention & control*; D005260:Female; D005315:Fetal Diseases / Q000517:prevention & control*; D006340:Heart Rate, Fetal / Q000187:drug effects*; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy; D011262:Pregnancy Trimester, Second; D015742:Propofol / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol