title: Calciphylaxis causing digital, gangrene in end stage renal disease: a case report and review.
abstract: Calcific uraemic arteriolopathy (CUA), a potentially life-threatening vasculopathy of the skin and subcutaneous tissues is rarely associated with advanced chronic kidney disease (CKD) particularly in patients on haemodialysis. It is more frequently reported in whites than in blacks and commonly accompanies hyperphosphataemia, elevated calcium-phosphate product and marked secondary hyperparathyroidism. We report a rare case of CUA that complicated end stage renal disease secondary to obstructive uropathy in a 68 year old Nigerian. The risk factors for CUA, diagnosis, management and our peculiar limitations were reviewed and discussed.
authors.affiliation: Renal Unit, Department of Medicine, Obafemi Awolowo University Teaching Hospitals Complex, P.M.B 5538, Ile-Ife, Osun State, Nigeria.
authors.forename: A A
authors.initials: AA
authors.lastname: Sanusi
authors.forename: F A
authors.initials: FA
authors.lastname: Arogundade
authors.forename: A I
authors.initials: AI
authors.lastname: Udo
authors.forename: M O
authors.initials: MO
authors.lastname: Hassan
authors.forename: O
authors.initials: O
authors.lastname: Oyewole
authors.forename: T
authors.initials: T
authors.lastname: Kolawole
authors.forename: A
authors.initials: A
authors.lastname: Akinsola
mesh_terms: D000368:Aged; D002115:Calciphylaxis / Q000150:complications* / Q000209:etiology / Q000628:therapy; D005734:Gangrene / Q000209:etiology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D007866:Leg / Q000473:pathology; D008297:Male; D012307:Risk Factors; D014034:Toes / Q000473:pathology*; D014511:Uremia / Q000150:complications