title: [Biological properties of Lactobacillus surface proteins].
abstract: Lactobacillus, a genus of Gram-positive bacteria, includes many strains of probiotic microflora. Probiotics, by definition, are living microorganisms that exert beneficial effects on the host organism. The morphology and physiology of the Lactobacillus bacterial genus are described. The structure of the cell wall of Gram-positive bacteria is discussed. The surface S-layer of Lactobacillus composed of proteins (SLP) with low molecular mass is presented. Cell surface proteins participating in the regulation of growth and survival of the intestinal epithelium cells are characterized. The influence of stress factors such as increased temperature, pH, and enzymes of gastric and pancreatic juice on SLP expression is described. The ability of binding of heavy metal ions by S-layer proteins is discussed. The characteristics of these structures, including the ability to adhere to epithelial cells, and the inhibition of invasion of pathogenic microflora of type Shigella, Salmonella, Escherichia coli and Clostridium and their toxins, are presented.
authors.affiliation: Laboratorium Mikrobiologii Lekarskiej, Instytut Immunologii i Terapii Doświadczalnej PAN im. L. Hirszfelda, Wrocław, Poland.
authors.forename: Barbara
authors.initials: B
authors.lastname: Buda
authors.forename: Ewa
authors.initials: E
authors.lastname: Dylus
authors.forename: Sabina
authors.initials: S
authors.lastname: Górska-Frączek
authors.forename: Ewa
authors.initials: E
authors.lastname: Brzozowska
authors.forename: Andrzej
authors.initials: A
authors.lastname: Gamian
mesh_terms: D001422:Bacterial Adhesion; D001426:Bacterial Proteins / Q000378:metabolism*; D002473:Cell Wall / Q000378:metabolism*; D004847:Epithelial Cells / Q000382:microbiology; D007413:Intestinal Mucosa / Q000382:microbiology; D007778:Lactobacillus / Q000378:metabolism*; D008562:Membrane Glycoproteins / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D008562:Membrane Glycoproteins; C055764:S-layer proteins; C418866:surface-binding protein, Lactobacillus