title: A nanospherical polymer as an MRI sensor without paramagnetic or superparamagnetic species.
abstract: We report here a nanospherical polymer consisting of methacrylic acid and N,N'-methylenebisacrylamide, which works as a metal-free magnetic resonance imaging (MRI) sensor for pH. The nanospherical polymer gave a lower signal T2-weighted MRI image with decreasing pH. In contrast, it had little effect on the T1-weighted MRI image.
authors.affiliation: Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. kkikuchi@mls.eng.osaka-u.ac.jp.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Okada
authors.forename: Shin
authors.initials: S
authors.lastname: Mizukami
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Matsumura
authors.forename: Yoshichika
authors.initials: Y
authors.lastname: Yoshioka
authors.forename: Kazuya
authors.initials: K
authors.lastname: Kikuchi
mesh_terms: D000178:Acrylamides / Q000737:chemistry*; D003287:Contrast Media / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008689:Methacrylates / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure
chemical_list: D000178:Acrylamides; D003287:Contrast Media; D008689:Methacrylates; C008384:methacrylic acid; C021221:N,N'-methylenebisacrylamide