title: Massive lipid exudation and retinal detachment after combined brachytherapy and transpupillary thermotherapy in choroidal melanoma.
abstract: METHODS
  A 59 year-old male with choroidal melanoma in the left eye who underwent plaque brachytherapy (iodine 125). One week after surgery, massive exudation with retinal detachment and lipid exudation was observed. Evolution was assessed with funduscopy and ultrasound every month. Nine months after surgery transpupillary thermotherapy (TTT) was performed over the fluid-free irradiated residual tumour. Three months after this procedure, new retinal breaks appeared in the treated area with vitreous seeding that required enucleation.
  
  
  CONCLUSIONS
  Combined treatment with plaque brachytherapy and TTT may associate severe complications that may require enucleation of the involved eye.
authors.affiliation: Departamento de Oftalmología, Clínica Universidad de Navarra (C.U.N.), Pamplona, Spain. jzarranz@hotmail.com
authors.forename: J
authors.initials: J
authors.lastname: Zarranz-Ventura
authors.forename: A
authors.initials: A
authors.lastname: Salinas-Alamán
authors.forename: J
authors.initials: J
authors.lastname: Barrio-Barrio
authors.forename: E
authors.initials: E
authors.lastname: de Nova
authors.forename: E
authors.initials: E
authors.lastname: Bonet
authors.forename: A
authors.initials: A
authors.lastname: García-Layana
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects*; D002830:Choroid Neoplasms / Q000628:therapy*; D003131:Combined Modality Therapy; D005122:Exudates and Transudates; D006801:Humans; D006979:Hyperthermia, Induced / Q000009:adverse effects* / Q000379:methods; D008297:Male; D008545:Melanoma / Q000628:therapy*; D008875:Middle Aged; D011680:Pupil; D012163:Retinal Detachment / Q000209:etiology*