title: Synthesis, characterization and cytotoxic activity on breast cancer cells of new half-titanocene derivatives.
abstract: A series of novel titanocene-complexes has been prepared and evaluated for their growth regulatory effects in MCF7 and SkBr3 breast cancer cells. The capability of some of these compound to elicit relevant repressive effects on cancer cell growth could be taken into account towards novel pharmacological approaches in cancer therapy.
authors.affiliation: Department of Pharmaceutical and Biomedical Sciences, University of Salerno, Italy.
authors.forename: Esther
authors.initials: E
authors.lastname: Sirignano
authors.forename: Carmela
authors.initials: C
authors.lastname: Saturnino
authors.forename: Antonio
authors.initials: A
authors.lastname: Botta
authors.forename: Maria Stefania
authors.initials: MS
authors.lastname: Sinicropi
authors.forename: Anna
authors.initials: A
authors.lastname: Caruso
authors.forename: Assunta
authors.initials: A
authors.lastname: Pisano
authors.forename: Rosamaria
authors.initials: R
authors.lastname: Lappano
authors.forename: Marcello
authors.initials: M
authors.lastname: Maggiolini
authors.forename: Pasquale
authors.initials: P
authors.lastname: Longo
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000627:therapeutic use / Q000633:toxicity; D001943:Breast Neoplasms / Q000188:drug therapy; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D005260:Female; D006801:Humans; D061986:MCF-7 Cells; D009942:Organometallic Compounds / Q000737:chemistry* / Q000627:therapeutic use / Q000633:toxicity
chemical_list: D000970:Antineoplastic Agents; D009942:Organometallic Compounds; C406884:titanocene