title: Diagnostic yield of EBUS-TBNA for the evaluation of centrally located peribronchial pulmonary lesions.
abstract: BACKGROUND
  The purpose of this study was to evaluate the diagnostic yield of endobronchial ultrasound with real-time-guided transbronchial needle aspiration (EBUS-TBNA), endobronchial forceps biopsy (EBBx), and 2D fluoroscopic-guided transbronchial forceps biopsy (TBLBx) for centrally located peribronchial lung lesions.
  
  
  METHODS
  A retrospective chart review of consecutive patients who underwent EBUS-TBNA of centrally located peribronchial lesions, that is, medial margin of the mass within inner third of hemithorax by computerized tomography scan. Patients who underwent EBUS-TBNA for lymph node sampling were excluded.
  
  
  RESULTS
  Thirty-two cases met the inclusion criteria. The mean age was 69±12 years. Sixteen (50%) were male patients. Of the 32 EBUS-TBNA cases, 13 underwent concomitant TBLBx (group 1), 8 had concomitant EBBx (group 2), and 11 had EBUS-TBNA alone (group 3). In group 1, the diagnostic yield of EBUS-TBNA was 95% (n=12/13), whereas the yield of TBLBx was 61% (n=8/13). In group 2, the diagnostic yield of EBUS-TBNA was 100% (n=8/8), whereas EBBx was positive in 75% (n=6/8). In group 3, the diagnostic yield of EBUS-TBNA was 91% (n=10/11). Overall diagnostic yield of EBUS-TBNA of centrally located peribronchial lung lesions was 94% (n=30/32).
  
  
  CONCLUSIONS
  Where available, EBUS-TBNA of centrally located peribronchial lung lesions should be given a strong consideration given its high diagnostic yield.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, University of Florida College of Medicine, Jacksonville, FL 32209, USA. hammad.bhatti@jax.ufl.edu
authors.forename: Hammad A
authors.initials: HA
authors.lastname: Bhatti
authors.forename: Abubakar
authors.initials: A
authors.lastname: Bajwa
authors.forename: Junaid A
authors.initials: JA
authors.lastname: Bhatti
authors.forename: James
authors.initials: J
authors.lastname: Cury
authors.forename: Adil
authors.initials: A
authors.lastname: Shujaat
authors.forename: Lisa
authors.initials: L
authors.lastname: Jones
authors.forename: Faisal
authors.initials: F
authors.lastname: Usman
mesh_terms: D000368:Aged; D001980:Bronchi; D061765:Endoscopic Ultrasound-Guided Fine Needle Aspiration; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D012189:Retrospective Studies