title: [Mesoporous silica nanoparticles for cancer theranostic drug delivery].
abstract: Mesoporous silica nanoparticles as drug carrier have become the new hot point in the field of biomedical application in recent years. This review focuses on the more recent developments and achievements on experimental design aspect of mesoporous silica nanoparticles with cancer diagnosis and therapy. The key advances of functionalization strategies of mesoporous silica nanoparticles with controlled release, tumor targeting and overcoming multidrug resistance are discussed in particular. Mesoporous silica nanoparticles as unique delivery systems have the potential to provide significantly a sound platform for cancer theranostic application.
authors.affiliation: Department of Radiology, Jinling Hospital, Nanjing 210002, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Wang
authors.forename: Zhao-Gang
authors.initials: ZG
authors.lastname: Teng
authors.forename: Xiao-Yin
authors.initials: XY
authors.lastname: Huang
authors.forename: Guang-Ming
authors.initials: GM
authors.lastname: Lu
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D018432:Drug Resistance, Multiple; D019008:Drug Resistance, Neoplasm; D006801:Humans; D053758:Nanoparticles; D009369:Neoplasms / Q000175:diagnosis / Q000628:therapy; D016062:Porosity; D012822:Silicon Dioxide
chemical_list: D000970:Antineoplastic Agents; D003692:Delayed-Action Preparations; D004337:Drug Carriers; D012822:Silicon Dioxide