title: Management of hip involvement in ankylosing spondylitis.
abstract: Ankylosing spondylitis (AS) is an inflammatory rheumatologic disease characterized by inflammation and progressive structural damage of the affected joints. Hip involvement often results in severe deformities and significant impairment on function. Although, tremendous progress has been made in conservative management for AS, effective prevention strategies for hip involvement and long-term need for total hip arthroplasty (THA) remain indefinite. When hip involvement has progressed to intractable pain and disability, THA is still the most effective treatment strategy to relieve pain and restore function. However, certain AS-specific problems regarding "preoperative preparation," "intraoperative difficulties," "perioperative pharmacological management," "postoperative physiotherapy," "operation benefits," and "operation complications" need more concern and further discussion.
authors.affiliation: Department of Orthopaedic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province 510515, China.
authors.forename: Mingqiang
authors.initials: M
authors.lastname: Guan
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
authors.forename: Liang
authors.initials: L
authors.lastname: Zhao
authors.forename: Jun
authors.initials: J
authors.lastname: Xiao
authors.forename: Zhihan
authors.initials: Z
authors.lastname: Li
authors.forename: Zhanjun
authors.initials: Z
authors.lastname: Shi
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D018501:Antirheumatic Agents / Q000627:therapeutic use; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D006615:Hip / Q000503:physiopathology; D006621:Hip Joint / Q000503:physiopathology; D006801:Humans; D007249:Inflammation; D010146:Pain / Q000601:surgery; D026741:Physical Therapy Modalities; D057234:Preoperative Period; D011788:Quality of Life; D013167:Spondylitis, Ankylosing / Q000473:pathology* / Q000601:surgery / Q000628:therapy*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D018501:Antirheumatic Agents; D014409:Tumor Necrosis Factor-alpha