title: Endoscopic snare papillectomy: a possible radical treatment for a subgroup of T1 ampullary adenocarcinomas.
abstract: Pancreaticoduodenectomy is the standard care for invasive ampullary adenocarcinomas. However, endoscopic snare papillectomy (ESP) might play a curative role in very selected patients. We studied a series of 15 patients with T1 ampullary adenocarcinoma who were treated by ESP alone and followed up for a mean of 29.6 ± 21.9 months (range 8 - 81 months). ESP was curative for eight patients (57.1 %). No tumor-related death was observed in patients with a cancer infiltration depth of ≤ 4 mm. According to this preliminary experience, we suggest that this measurable variable threshold should be considered as a possible basis for future large-scale studies.
authors.affiliation: Institute of Pathology, Policlinico A. Gemelli, Università Cattolica del Sacro Cuore, 00168 Rome, Italy. gianluigipetrone@hotmail.com
authors.forename: G
authors.initials: G
authors.lastname: Petrone
authors.forename: R
authors.initials: R
authors.lastname: Ricci
authors.forename: P
authors.initials: P
authors.lastname: Familiari
authors.forename: F
authors.initials: F
authors.lastname: Inzani
authors.forename: M
authors.initials: M
authors.lastname: Matsuoka
authors.forename: M
authors.initials: M
authors.lastname: Mutignani
authors.forename: G
authors.initials: G
authors.lastname: Delle Fave
authors.forename: G
authors.initials: G
authors.lastname: Costamagna
authors.forename: G
authors.initials: G
authors.lastname: Rindi
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery*; D000368:Aged; D000369:Aged, 80 and over; D014670:Ampulla of Vater; D003138:Common Bile Duct Neoplasms / Q000473:pathology* / Q000601:surgery*; D018572:Disease-Free Survival; D004384:Duodenoscopy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D012189:Retrospective Studies