title: Synthesis of new 1,2,3-triazole derivatives of uracil and thymine with potential inhibitory activity against acidic corrosion of steels.
abstract: Ten 1,4-disubstituted 1,2,3-triazoles were synthesized from one of 1-(azido-methyl)benzene, 1-(azidomethyl)-4-fluorobenzene, 1-(azidomethyl)-4-chlorobenzene, 1-(azidomethyl)-4-bromobenzene or 1-(azidomethyl)-4-iodobenzene, generated in situ from sodium azide and the corresponding benzyl halide, and dipropargyl uracil or dipropargyl thymine. Optimal experimental conditions were established for the conventional click chemistry. The corrosion inhibiting properties of some of these compounds, which were determined by means of an electrochemical technique, are also presented.
authors.affiliation: Departamento de Ciencias Básicas, Universidad Autónoma Metropolitana, Av. San Pablo No. 180, México D.F., C.P. 02200, Mexico. gns@correo.azc.uam.mx
authors.forename: Guillermo E
authors.initials: GE
authors.lastname: Negrón-Silva
authors.forename: Rodrigo
authors.initials: R
authors.lastname: González-Olvera
authors.forename: Deyanira
authors.initials: D
authors.lastname: Angeles-Beltrán
authors.forename: Nidia
authors.initials: N
authors.lastname: Maldonado-Carmona
authors.forename: Araceli
authors.initials: A
authors.lastname: Espinoza-Vázquez
authors.forename: Manuel E
authors.initials: ME
authors.lastname: Palomar-Pardavé
authors.forename: Mario A
authors.initials: MA
authors.lastname: Romero-Romo
authors.forename: Rosa
authors.initials: R
authors.lastname: Santillan
mesh_terms: D057930:Click Chemistry; D003343:Corrosion; D055664:Electrochemical Techniques; D006863:Hydrogen-Ion Concentration; D019906:Nuclear Magnetic Resonance, Biomolecular; D013232:Steel / Q000737:chemistry*; D013941:Thymine / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*; D014498:Uracil / Q000737:chemistry*
chemical_list: D014230:Triazoles; D013232:Steel; D014498:Uracil; D013941:Thymine