title: Evaluation of the effect of low level laser on prevention of chemotherapy-induced mucositis.
abstract: Radiotherapy in the head and neck region and chemotherapy might give rise to oral mucositis which is a severe and painful inflammation. There is no known definite cure for mucositis. A number of studies have attempted to evaluate the effect of low-power laser on radiotherapy- and chemotherapy-induced mucositis. The present study was undertaken to evaluate the effect of low-power laser on the prevention of mucositis, xerostomia and pain as a result of chemotherapy. The subjects in this double-blind randomized controlled study were 24 adult patients who underwent chemotherapy during 2009-2010. The results showed that low-power laser was able to decrease the effect of chemotherapy on oral mucositis, xerostomia and pain in a variety of malignancies (P&lt;0.05). It can be concluded that low-power laser might decrease the intensity of mucositis.
authors.affiliation: Brain and Spinal Injury Research Center, Tehran Universityof Medical Sciences, Tehran, Iran.
authors.forename: Farshid
authors.initials: F
authors.lastname: Arbabi-Kalati
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Arbabi-Kalati
authors.forename: Tahora
authors.initials: T
authors.lastname: Moridi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D004311:Double-Blind Method; D005260:Female; D006258:Head and Neck Neoplasms / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D028022:Low-Level Light Therapy; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000139:chemically induced / Q000517:prevention & control*; D013280:Stomatitis / Q000139:chemically induced* / Q000517:prevention & control*; D016896:Treatment Outcome; D014987:Xerostomia / Q000139:chemically induced / Q000517:prevention & control*; D055815:Young Adult