title: [Supportive therapy for locally advanced cancer of the oral mucosa].
abstract: The article discusses the practice of detoxication therapy to minimize undesirable toxic effects during chemo- and radiotherapy for locally advanced cancer of the oral mucosa in 88 patients treated with 1.5% solution of reamberine. There was a significant improvement in the parameters of liver function, as well as in the general wellbeing of patients. We analyzed the main symptoms of the toxicity of chemo- and radiotherapy in both groups. Inclusion of the reamberine solution as supportive therapy for cancer patients who were receiving chemo- and radiotherapy for cancer of the oral mucosa allowed reducing the number and severity of toxic complications.
authors.forename: V M
authors.initials: VM
authors.lastname: Ivanov
authors.forename: G G
authors.initials: GG
authors.lastname: Matiakin
authors.forename: O V
authors.initials: OV
authors.lastname: Ivanova
authors.forename: M V
authors.initials: MV
authors.lastname: Sheĭkin
authors.forename: M G
authors.initials: MG
authors.lastname: Romantsov
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects*; D017024:Chemotherapy, Adjuvant / Q000009:adverse effects; D005260:Female; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D008536:Meglumine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008875:Middle Aged; D009061:Mouth Mucosa / Q000187:drug effects*; D009062:Mouth Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects; D012720:Severity of Illness Index; D013280:Stomatitis / Q000139:chemically induced / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control*; D013386:Succinates / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: C549374:Reamberin; D013386:Succinates; D008536:Meglumine