title: Phenytoin-induced gingival enlargement: a dental awakening for patients with epilepsy.
abstract: Drug-induced gingival enlargement is the term now used to describe medication-related gingival hypertrophy or hyperplasia, a condition commonly induced by three main classes of drugs: anticonvulsants, antihypertensive calcium channel blockers and the immunosuppressant cyclosporine. The pathogenesis of drug-induced gingival enlargement is uncertain and there appears to be no unifying hypothesis that links together the three commonly implicated drugs. Phenytoin-induced gingival overgrowth is a well known and frequently reported gingival lesion, which was first detected in 1939. This case report consists of phenytoin usage, duration and poor oral hygiene.
authors.affiliation: Department of Oral Medicine and Radiology, Kothiwal Dental College & Research Centre, Moradabad, Uttar Pradesh, India.
authors.forename: Ravi Prakah Sasankoti
authors.initials: RP
authors.lastname: Mohan
authors.forename: Khushboo
authors.initials: K
authors.lastname: Rastogi
authors.forename: Rajarshi
authors.initials: R
authors.lastname: Bhushan
authors.forename: Sankalp
authors.initials: S
authors.lastname: Verma
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects*; D004827:Epilepsy / Q000188:drug therapy*; D005885:Gingival Hyperplasia / Q000139:chemically induced*; D006801:Humans; D008297:Male; D010672:Phenytoin / Q000009:adverse effects*
chemical_list: D000927:Anticonvulsants; D010672:Phenytoin