title: [Transplantation of autologous labial salivary glands for severe dry eye].
abstract: OBJECTIVE
  Autologous labial salivary gland transplantation has been a promising alternative for the treatment of severe dry eye. In this article, we describe the results of the ocular surface changes after labial salivary gland transplantation and investigate the feasibility of this treatment.
  
  
  METHODS
  The results of this technique in 8 patients (eyes) who suffered from severe dry eye were prospectively analyzed after surgery (follow-up of 6 months). The best-corrected visual acuity, Schirmer I test, degree of discomfort, usage of pharmaceutical tear substitutes, tear interferometry and slit lamp examination were investigated at different time before and after surgery.
  
  
  RESULTS
  All grafts remained viable and the survival rate is 100%. All patients showed significant increase in the Schirmer's test and they expressed great improvement in their ocular discomfort. The use of artificial tear substitutes was reduced because of the increased ocular surface lubrication.
  
  
  CONCLUSIONS
  Although the authors' long-term experience still is limited, we believe that the procedure is a promising alternative approach for severe dry eye.
authors.affiliation: Beijing Ophthalmol & Visual Sciences Key Laboratory, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100710, China.
authors.forename: Shun-rong
authors.initials: SR
authors.lastname: Luo
authors.forename: Liu-he
authors.initials: LH
authors.lastname: Zou
authors.forename: Chao
authors.initials: C
authors.lastname: Yan
authors.forename: Zhi-qiang
authors.initials: ZQ
authors.lastname: Pan
authors.forename: Jing-ming
authors.initials: JM
authors.lastname: Liu
authors.forename: Zhi-yuan
authors.initials: ZY
authors.lastname: Chen
authors.forename: Wei-hong
authors.initials: WH
authors.lastname: Yin
mesh_terms: D000293:Adolescent; D000328:Adult; D015352:Dry Eye Syndromes / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa; D012469:Salivary Glands / Q000637:transplantation*; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D055815:Young Adult