title: [Pharmacological researches of curcumin solid dispersions in treatment of cancer].
abstract: OBJECTIVE
  To investigate the anticancer effect of curcumin Solid Dispersions (SDs).
  
  
  METHODS
  Curcumin SDs were prepared by patent technology. The anticancer effect of curcumin SDs were investigated by vivo and vitro tests of SCG-7901, BEL-7402, S-180 and Ehrlich ascites tumor models.
  
  
  RESULTS
  The results showed that Curcumin SDs had markedly anticancer effect and could improve the anticancer effect of cisplatin.
  
  
  CONCLUSIONS
  Curcumin SDs could be developed into one kind of adjuvant drug for anticancer, as it has markedly anticancer effect, and could improve the anticancer effects of cisplatin.
authors.affiliation: Laboratory of Traditional Chinese Medicine and Marine Drugs, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China. lssmxt@mail.sysu.edu.cn
authors.forename: Xue-Ting
authors.initials: XT
authors.lastname: Mei
authors.forename: Dong-Hui
authors.initials: DH
authors.lastname: Xu
authors.forename: Xue-Ni
authors.initials: XN
authors.lastname: He
authors.forename: Yong-Chang
authors.initials: YC
authors.lastname: Lu
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D060326:Chemistry Techniques, Synthetic; D002945:Cisplatin / Q000008:administration & dosage / Q000494:pharmacology*; D030024:Curcuma / Q000737:chemistry; D003474:Curcumin / Q000008:administration & dosage / Q000737:chemistry* / Q000494:pharmacology*; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology*; D012995:Solubility
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D003474:Curcumin; D002945:Cisplatin