title: Immunoglobulin G4-related disease mimicking asthma.
abstract: Immunoglobulin (Ig) G4-related disease (also known as 'IgG4-related sclerosing disease', 'IgG4-related systemic disease' or 'hyper-IgG4-disease') is a recently recognized systemic fibroinflammatory disease associated with IgG4-positive plasma cells in tissue lesions. IgG4-related disease was initially described as autoimmune pancreatitis, but it is now known to affect virtually any organ. The authors describe a patient presenting with multi-organ manifestations, including airway inflammation mimicking asthma, pulmonary parenchymal infiltrates, intrathoracic lymphadenopathy, submandibular gland swelling and a kidney mass.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA. sekiguchi.hiroshi@mayo.edu
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sekiguchi
authors.forename: Ryohei
authors.initials: R
authors.lastname: Horie
authors.forename: Timothy R
authors.initials: TR
authors.lastname: Aksamit
authors.forename: Eunhee S
authors.initials: ES
authors.lastname: Yi
authors.forename: Jay H
authors.initials: JH
authors.lastname: Ryu
mesh_terms: D000328:Adult; D001249:Asthma / Q000175:diagnosis*; D001327:Autoimmune Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D006942:Hypergammaglobulinemia / Q000175:diagnosis*; D007074:Immunoglobulin G / Q000276:immunology*; D008206:Lymphatic Diseases / Q000175:diagnosis*; D008297:Male; D012793:Sialadenitis / Q000175:diagnosis*
chemical_list: D007074:Immunoglobulin G