title: [FibroScan can be used to diagnose the size of oesophageal varices in patients with HBV-related cirrhosis].
abstract: OBJECTIVE
  To study ability of FibroScan (FS) in diagnosing the size of oesophageal varices (OV) in patients with HBV-related cirrhosis.
  
  
  METHODS
  A total of 158 patients with HBV-related liver cirrhosis were enrolled in the study. The relation between the presence of OV assessed by endoscopy, and liver stiffness measurement by Fibroscan was studied, and ROC curves were drawn to assess the diagnostic ability of FS value.
  
  
  RESULTS
  For the patients without OV, mild OV, moderate OV, and severe OV, their corresponding FS values were (21.7 +/- 9.9) kPa, (32.1 +/- 13.6) kPa, (42.3 +/- 20.0) kPa and (54.5 +/- 16.2) kPa, respectively. Significant difference was found among the groups (P < 0.001) and also between any two groups (P < 0.05). ROC curve for the diagnosis of with vs. without OV, <moderate vs. > moderate OV, and < severe vs. severe OV were 0.798 (95% CI: 73.1%-86.5%), 0.823 (95% CI: 74.5%-90.0%) and 0.879 (95% CI: 80.8%-95.0%), respectively, with corresponding FS cut-off value of 23.3 kPa, 31.5 kPa and 34.6 kPa.
  
  
  CONCLUSIONS
  Liver stiffness measurement allows to predict the sizes of oesophageal varices in patients with HBV-related cirrhosis.
authors.affiliation: Medical School of Chinese PLA, Beijing, China.
authors.forename: Fan
authors.initials: F
authors.lastname: Li
authors.forename: Tao
authors.initials: T
authors.lastname: Yan
authors.forename: Jian
authors.initials: J
authors.lastname: Zhang
authors.forename: Qing
authors.initials: Q
authors.lastname: Shao
authors.forename: Bing
authors.initials: B
authors.lastname: Li
authors.forename: Zhong-Bing
authors.initials: ZB
authors.lastname: Li
authors.forename: Guo-Feng
authors.initials: GF
authors.lastname: Chen
mesh_terms: D000328:Adult; D054459:Elasticity Imaging Techniques / Q000379:methods*; D004932:Esophageal and Gastric Varices / Q000175:diagnosis* / Q000000981:diagnostic imaging* / Q000209:etiology; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D008103:Liver Cirrhosis / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged