title: Beware the increasing cost and number of orphan drugs.
authors.affiliation: ESilverman@ManagedCareMag.com
authors.forename: Ed
authors.initials: E
authors.lastname: Silverman
mesh_terms: D001688:Biological Products / Q000191:economics / Q000627:therapeutic use; D003365:Costs and Cost Analysis; D017277:Drug Approval / Q000706:statistics & numerical data; D016527:Drug Costs / Q000706:statistics & numerical data* / Q000639:trends; D006801:Humans; D007349:Insurance, Health, Reimbursement; D009965:Orphan Drug Production / Q000191:economics* / Q000706:statistics & numerical data; D011306:Prescription Fees / Q000706:statistics & numerical data* / Q000639:trends; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D001688:Biological Products