title: A novel acetylcholine bioensor and its electrochemical behavior.
abstract: A novel type of acetylcholine electrochemical biosensor was successfully fabricated by dropping beta-cyclodextrin solution, acetylcholinesterase solution and Nafion-methanol solution to the homemade nano-porous pseudo carbon paste electrode (nano-PPCPE) as working electrode, and then the electrochemical behavior of the as-prepared biosensor was studied through the acetylthiocholine iodide (ATChI). It was shown that the modified nano-PPCPE displays a high selectivity and sensitivity. The acetylcholine biosensor showed the linear range from 5 x 10(-6) M to 2 x 10(-4) M with the detection limit of 1.5 x 10(-7) M.
authors.affiliation: Key Laboratory of Green Packaging and Application of Biological Nanotechnology, Hunan University of Technology, Zhuzhou 412007, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Yan
authors.initials: Y
authors.lastname: Deng
authors.forename: Song
authors.initials: S
authors.lastname: Li
authors.forename: Hongna
authors.initials: H
authors.lastname: Liu
authors.forename: Zhuoxuan
authors.initials: Z
authors.lastname: Lu
authors.forename: Liming
authors.initials: L
authors.lastname: Zhang
authors.forename: Lin
authors.initials: L
authors.lastname: Lin
authors.forename: Lijian
authors.initials: L
authors.lastname: Xu
mesh_terms: D000109:Acetylcholine / Q000032:analysis*; D015374:Biosensing Techniques / Q000295:instrumentation*; D002244:Carbon / Q000737:chemistry; D004560:Electricity; D055664:Electrochemical Techniques / Q000295:instrumentation*; D004566:Electrodes; D006863:Hydrogen-Ion Concentration; D053758:Nanoparticles / Q000737:chemistry; D016062:Porosity
chemical_list: D002244:Carbon; D000109:Acetylcholine