title: Unprecedented construction of C═C double bonds via Ir-catalyzed dehydrogenative and dehydrative cross-couplings.
abstract: Unprecedented constructions of C═C double bonds have been achieved by Ir-catalyzed intramolecular dehydrogenative and dehydrative cross-coupling of tertiary amines and ketones. The reactions are proposed to proceed via an Ir-mediated C-H activation mechanism.
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University , Guangzhou 510006, China, and Liverpool Centre for Materials & Catalysis, Department of Chemistry, University of Liverpool , Liverpool L69 7ZD, U.K.
authors.forename: Shao-zhen
authors.initials: SZ
authors.lastname: Nie
authors.forename: Xiang
authors.initials: X
authors.lastname: Sun
authors.forename: Wen-tao
authors.initials: WT
authors.lastname: Wei
authors.forename: Xue-jing
authors.initials: XJ
authors.lastname: Zhang
authors.forename: Ming
authors.initials: M
authors.lastname: Yan
authors.forename: Jian-liang
authors.initials: JL
authors.lastname: Xiao
mesh_terms: D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D007495:Iridium / Q000737:chemistry*; D007659:Ketones / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000588:Amines; D007659:Ketones; D007495:Iridium