title: Mycobacterial lineages causing pulmonary and extrapulmonary tuberculosis, Ethiopia.
abstract: Molecular typing of 964 specimens from patients in Ethiopia with lymph node or pulmonary tuberculosis showed a similar distribution of Mycobacterium tuberculosis strains between the 2 disease manifestations and a minimal role for M. bovis. We report a novel phylogenetic lineage of M. tuberculosis strongly associated with the Horn of Africa.
authors.affiliation: Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
authors.forename: Rebuma
authors.initials: R
authors.lastname: Firdessa
authors.forename: Stefan
authors.initials: S
authors.lastname: Berg
authors.forename: Elena
authors.initials: E
authors.lastname: Hailu
authors.forename: Esther
authors.initials: E
authors.lastname: Schelling
authors.forename: Balako
authors.initials: B
authors.lastname: Gumi
authors.forename: Girume
authors.initials: G
authors.lastname: Erenso
authors.forename: Endalamaw
authors.initials: E
authors.lastname: Gadisa
authors.forename: Teklu
authors.initials: T
authors.lastname: Kiros
authors.forename: Meseret
authors.initials: M
authors.lastname: Habtamu
authors.forename: Jemal
authors.initials: J
authors.lastname: Hussein
authors.forename: Jakob
authors.initials: J
authors.lastname: Zinsstag
authors.forename: Brian D
authors.initials: BD
authors.lastname: Robertson
authors.forename: Gobena
authors.initials: G
authors.lastname: Ameni
authors.forename: Amanda J
authors.initials: AJ
authors.lastname: Lohan
authors.forename: Brendan
authors.initials: B
authors.lastname: Loftus
authors.forename: Iñaki
authors.initials: I
authors.lastname: Comas
authors.forename: Sebastien
authors.initials: S
authors.lastname: Gagneux
authors.forename: Rea
authors.initials: R
authors.lastname: Tschopp
authors.forename: Lawrence
authors.initials: L
authors.lastname: Yamuah
authors.forename: Glyn
authors.initials: G
authors.lastname: Hewinson
authors.forename: Stephen V
authors.initials: SV
authors.lastname: Gordon
authors.forename: Douglas B
authors.initials: DB
authors.lastname: Young
authors.forename: Abraham
authors.initials: A
authors.lastname: Aseffa
mesh_terms: D016000:Cluster Analysis; D005002:Ethiopia; D005798:Genes, Bacterial; D006801:Humans; D008198:Lymph Nodes / Q000382:microbiology; D058885:Multilocus Sequence Typing; D009169:Mycobacterium tuberculosis / Q000235:genetics* / Q000302:isolation & purification; D009333:Neck; D010802:Phylogeny; D020641:Polymorphism, Single Nucleotide; D014388:Tuberculosis, Lymph Node / Q000382:microbiology*; D014397:Tuberculosis, Pulmonary / Q000382:microbiology*
keywords: Ethiopia; Mycobacterium bovis; Mycobacterium tuberculosis; TB lymphadenitis; Tuberculosis and other mycobacteria; bacteria; bovine; cervical lymph nodes; extrapulmonary tuberculosis; lineage; lymph nodes; pulmonary tuberculosis; tuberculosis; zoonoses; zoonotic transmission