title: Vaccine research, development, and innovation in Brazil: a translational science perspective.
abstract: This article examines the Brazilian innovation policy for vaccines and its impact on infectious diseases, with emphasis on advances in translational science. The results indicate significant progress, with a rapid increase over the past two decades in the number of vaccine research groups, indicating scientific excellence. Advances and gaps in technological development and in public-private partnership initiatives were also identified. We stress the crucial role of partnerships, technology transfer, and targeted policies that could accelerate Brazil's participation in global vaccine research and development. We propose that new strategies should be urgently conceived to strengthen the links between the scientific and technological policies, the National Health System, and the National Immunizations Program in Brazil to provide access to low-cost vaccines to address major public health challenges. We also discuss the lessons learned from the Brazilian experience in the implementation of governmental policies on vaccine innovation that could be applicable to other developing countries.
authors.affiliation: Bio-Manguinhos, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil. akira@bio.fiocruz.br
authors.forename: Akira
authors.initials: A
authors.lastname: Homma
authors.forename: Amilcar
authors.initials: A
authors.lastname: Tanuri
authors.forename: Alberto J S
authors.initials: AJ
authors.lastname: Duarte
authors.forename: Ernesto
authors.initials: E
authors.lastname: Marques
authors.forename: Alexandre
authors.initials: A
authors.lastname: de Almeida
authors.forename: Reinaldo
authors.initials: R
authors.lastname: Martins
authors.forename: Jarbas B
authors.initials: JB
authors.lastname: Silva-Junior
authors.forename: Cristina
authors.initials: C
authors.lastname: Possas
mesh_terms: D001938:Brazil; D006078:Government Programs; D006291:Health Policy / Q000331:legislation & jurisprudence*; D006801:Humans; D017589:Immunization Programs / Q000331:legislation & jurisprudence / Q000706:statistics & numerical data; D062069:Inventions; D011634:Public Health; D055818:Public-Private Sector Partnerships; D018581:Technology Transfer; D057170:Translational Research, Biomedical; D014612:Vaccines
chemical_list: D014612:Vaccines