title: Periprosthetic metastasis: a rare cause for prosthetic loosening.
abstract: Malignant periprosthetic metastasis is a very rare yet important cause of painful joint arthroplasty. This study presents a case in which periprosthetic osteolysis following total hip replacement (THR) occurred as a result of metastatic mesothelioma. After a THR and revision THR, histopathology confirmed the diagnosis of metastatic mesothelioma. Primary lesion was identified using CT scan of the chest. Patient is receiving palliative chemotherapy.
authors.affiliation: Department of Trauma and Orthopaedic Surgery, Kettering General Hospital, Kettering, UK. dr.nagy@gmx.net
authors.forename: Mathias Thomas
authors.initials: MT
authors.lastname: Nagy
authors.forename: Andrew Fred
authors.initials: AF
authors.lastname: Young
authors.forename: Neshteman
authors.initials: N
authors.lastname: Gorgees
authors.forename: Richard Lawrence
authors.initials: RL
authors.lastname: Barrington
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D003937:Diagnosis, Differential; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008654:Mesothelioma / Q000000981:diagnostic imaging / Q000556:secondary*; D015207:Osteoarthritis, Hip / Q000000981:diagnostic imaging / Q000601:surgery*; D010014:Osteolysis / Q000000981:diagnostic imaging / Q000473:pathology*; D011475:Prosthesis Failure; D013902:Radiography, Thoracic; D012086:Reoperation; D014057:Tomography, X-Ray Computed