title: New profiles of posterior pole retinal thickness map in healthy Korean eyes measured by spectral-domain optical coherence tomography.
abstract: OBJECTIVE
  To analyze posterior pole retinal thickness using the new Spectralis HRA + OCT protocol and compare two commercially available spectral-domain optical coherence tomography instruments (Spectralis HRA + OCT and Cirrus HD-OCT) in young healthy eyes.
  
  
  METHODS
  Retinal thickness in 178 young healthy eyes was measured using the volume scan mode and Posterior Pole Asymmetry Analysis of the Spectralis HRA + OCT and the macular cube 512 × 128 protocol of the Cirrus HD-OCT. Topologic differences in posterior pole retinal thickness between the two spectral-domain optical coherence tomographies were compared, and the relationship between retinal thickness and age or refractive error/axial length was assessed.
  
  
  RESULTS
  Mean retinal thickness measurements in all 9 Early Treatment Diabetic Retinopathy Study Report areas were significantly greater with the Spectralis HRA + OCT than with the Cirrus HD-OCT (P < 0.001). Retinal thickness measured with the new Spectralis HRA + OCT protocol positively correlated with refractive error (P < 0.05) and negatively correlated with axial length (P < 0.05), mainly in the temporal areas. As axial length increased and refractive error decreased, retinal thickness decreased significantly at the outer temporal areas compared with the nasal areas (P < 0.05). Foveal thickness measured with the Spectralis HRA + OCT correlated significantly with refractive error (r = -0.151; P = 0.022) and axial length (r = 0.352; P < 0.001).
  
  
  CONCLUSIONS
  Posterior pole retinal thickness measurements in young healthy eyes should provide more detailed standard values for diagnosing and managing retinal disease.
authors.affiliation: *Department of Ophthalmology, Kyung Hee University Hospital, Kyung Hee University, Seoul, South Korea; †Department of Ophthalmology, School of Medicine, Kangwon National University, Chuncheon, South Korea; and ‡Department of Ophthalmology, Eulji University Hospital, Eulji University, Seoul, South Korea.
authors.forename: Kook Young
authors.initials: KY
authors.lastname: Kim
authors.forename: Hyung Woo
authors.initials: HW
authors.lastname: Kwak
authors.forename: Moosang
authors.initials: M
authors.lastname: Kim
authors.forename: Young Gyun
authors.initials: YG
authors.lastname: Kim
authors.forename: Seung-Young
authors.initials: SY
authors.lastname: Yu
mesh_terms: D000328:Adult; D044466:Asian People; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D009887:Ophthalmoscopy; D009929:Organ Size; D057972:Posterior Eye Segment / Q000033:anatomy & histology*; D011446:Prospective Studies; D012016:Reference Values; D056910:Republic of Korea; D012160:Retina / Q000033:anatomy & histology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult