title: ValiDichro: a website for validating and quality control of protein circular dichroism spectra.
abstract: Circular dichroism (CD) spectroscopy is widely used in structural biology as a technique for examining the structure, folding and conformational changes of proteins. A new server, ValiDichro, has been developed for checking the quality and validity of CD spectral data and metadata, both as an aid to data collection and processing and as a validation procedure for spectra to be included in publications. ValiDichro currently includes 25 tests for data completeness, consistency and quality. For each test that is done, not only is a validation report produced, but the user is also provided with suggestions for correcting or improving the data. The ValiDichro server is freely available at http://valispec.cryst.bbk.ac.uk/circularDichroism/ValiDichro/upload.html.
authors.affiliation: Institute of Structural and Molecular Biology, Birkbeck College, University of London, London WC1E 7HX, UK.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Woollett
authors.forename: Lee
authors.initials: L
authors.lastname: Whitmore
authors.forename: Robert W
authors.initials: RW
authors.lastname: Janes
authors.forename: B A
authors.initials: BA
authors.lastname: Wallace
mesh_terms: D002942:Circular Dichroism / Q000592:standards*; D020407:Internet; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry; D011786:Quality Control; D012984:Software
chemical_list: D011506:Proteins