title: Micro/Nanometer-scale fiber with highly ordered structures by mimicking the spinning process of silkworm.
abstract: A new method for the microfluidic spinning of ultrathin fibers with highly ordered structures is proposed by mimicking the spinning mechanism of silkworms. The self-aggregation is driven by dipole-dipole attractions between polar polymers upon contact with a low-polarity solvent to form fibers with nanostrands. The induction of Kelvin-Helmholtz instabilities at the dehydrating interface between two miscible fluids generates multi-scale fibers in a single microchannel.
authors.affiliation: Department of Biomedical Engineering, College of Health Science, Korea University, Jeongeung-dong, Seongbuk-gu, Seoul, 136-703, Republic of Korea.
authors.forename: Su-Kyoung
authors.initials: SK
authors.lastname: Chae
authors.forename: Edward
authors.initials: E
authors.lastname: Kang
authors.forename: Ali
authors.initials: A
authors.lastname: Khademhosseini
authors.forename: Sang-Hoon
authors.initials: SH
authors.lastname: Lee
mesh_terms: D000464:Alginates / Q000737:chemistry; D000818:Animals; D032701:Biomimetics / Q000379:methods*; D012831:Bombyx; D020723:Glucuronic Acid / Q000737:chemistry; D006603:Hexuronic Acids / Q000737:chemistry; D055616:Microtechnology / Q000379:methods*; D057139:Nanofibers / Q000737:chemistry*; D017433:Protein Structure, Secondary; D047011:Silk / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D013314:Stress, Mechanical
chemical_list: D000464:Alginates; D006603:Hexuronic Acids; D047011:Silk; D012997:Solvents; D020723:Glucuronic Acid