title: Nanocarriers for oral drug delivery.
abstract: The oral route for delivery of pharmaceuticals is widely used and accepted. However, many biological therapeutics that have poor solubility, poor permeability, and/or poor stability in the gastrointestinal environment have poor oral bioavailability and are therefore rarely used for oral drug delivery. In recent years, nanocarriers are widely used, which can provide an alternative solution for oral administration of these drugs. In this article, several nanocarriers (nanoparticles, micelles, liposomes, nanocrystals, carbon nanotubes, nanoemulsions, dendrimers, and nanospheres) for drug delivery systems have been designed based on different nanomaterials for oral drug delivery.
authors.affiliation: Department of Pharmaceutics, Shandong Institute of Pharmaceutical Industry, Jinan, Shandong, People's Republic of China. wodeyingwuzhou@126.com
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
authors.forename: Shuli
authors.initials: S
authors.lastname: Wang
authors.forename: Manhong
authors.initials: M
authors.lastname: Zhang
authors.forename: Jie
authors.initials: J
authors.lastname: Sun
mesh_terms: D000284:Administration, Oral; D004337:Drug Carriers / Q000008:administration & dosage* / Q000737:chemistry*; D016503:Drug Delivery Systems / Q000379:methods*; D006801:Humans; D053758:Nanoparticles / Q000008:administration & dosage* / Q000737:chemistry*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage* / Q000737:chemistry*; D012995:Solubility
chemical_list: D004337:Drug Carriers; D004364:Pharmaceutical Preparations