title: Six-month outcomes from living well with diabetes: A randomized trial of a telephone-delivered weight loss and physical activity intervention to improve glycemic control.
abstract: BACKGROUND
  Intensive lifestyle intervention trials in type 2 diabetes contribute evidence on what can be achieved under optimal conditions, but are less informative for translation in applied settings.
  
  
  OBJECTIVE
  Living Well with Diabetes is a telephone-delivered weight loss intervention designed for real-world delivery.
  
  
  METHODS
  This study is a randomized controlled trial of telephone counseling (n = 151) versus usual care (n = 151); 6-month primary outcomes of weight, physical activity, HbA1c; secondary diet outcomes; analysis was by adjusted generalized linear models.
  
  
  RESULTS
  Relative to usual care, telephone counseling participants had small but significantly better weight loss [-1.12 % of initial body weight; 95 % confidence interval (CI) -1.92, -0.33 %]; physical activity [relative rate (RR) = 1.30; 95 % CI, 1.08, 1.57]; energy intake reduction (-0.63 MJ/day; 95 % CI, -1.01, -0.25); and diet quality (3.72 points; 95 % CI, 1.77, 5.68), with no intervention effect for HbA1c (RR = 0.99; 95 % CI, 0.96, 1.01).
  
  
  CONCLUSIONS
  Results are discussed in light of challenges to intervention delivery.
authors.affiliation: The University of Queensland, School of Population Health, Cancer Prevention Research Centre, Level 3 Public Health Building, Herston Road, Herston, Brisbane, QLD, 4006, Australia, e.eakin@sph.uq.edu.au.
authors.forename: E G
authors.initials: EG
authors.lastname: Eakin
authors.forename: M M
authors.initials: MM
authors.lastname: Reeves
authors.forename: E
authors.initials: E
authors.lastname: Winkler
authors.forename: G N
authors.initials: GN
authors.lastname: Healy
authors.forename: D W
authors.initials: DW
authors.lastname: Dunstan
authors.forename: N
authors.initials: N
authors.lastname: Owen
authors.forename: A M
authors.initials: AM
authors.lastname: Marshal
authors.forename: K C
authors.initials: KC
authors.lastname: Wilkie
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism / Q000628:therapy*; D005247:Feeding Behavior / Q000523:psychology; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D038321:Glycemic Index; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D010353:Patient Education as Topic / Q000379:methods*; D013689:Telephone; D016896:Treatment Outcome; D061217:Weight Reduction Programs / Q000379:methods*
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human