title: 3-Aminophenyl boronic acid-functionalized CuInS2 quantum dots as a near-infrared fluorescence probe for the determination of dopamine.
abstract: Water-soluble CuInS2 ternary quantum dots (QDs) capped by mercaptopropionic acid were directly synthesized in aqueous solution. Consequently, the CuInS2 QDs were covalently linked to 3-aminophenyl boronic acid molecules to form the 3-aminophenyl boronic acid-functionalized CuInS2 QDs (F-CuInS2 QDs). The F-CuInS2 QDs had a fairly symmetric fluorescence emission centered at 736nm that was in the near-infrared region (NIR). The F-CuInS2 QDs containing boronic acid functional groups were reactive toward vicinal diols to form five- or six-member cyclic esters in an alkaline aqueous solution. The reaction would cause the fluorescence quenching, which could be used as a fluorescence probe for the determination of dopamine (DA). This assay could also probe other vicinal diols such as catechol, pyrogallol, and gallate, based on the fluorescence quenching of the F-CuInS2 QDs, and this assay was nearly unaffected by other phenol compounds such as phenol, resorcinol, and hydroquinone without the vicinal diol structures. The developed F-CuInS2 QDs were applied to the detection of DA in human serum samples with satisfactory results. Therefore, this experment provided a simple and sensitve NIR fluorescence probe for the detection of DA, catechol, pyrogallol, and gallate.
authors.affiliation: Department of Analytical Chemistry, College of Chemistry, Jilin University, Changchun, 130012, China.
authors.forename: Siyu
authors.initials: S
authors.lastname: Liu
authors.forename: Fanping
authors.initials: F
authors.lastname: Shi
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Zhao
authors.forename: Lu
authors.initials: L
authors.lastname: Chen
authors.forename: Xingguang
authors.initials: X
authors.lastname: Su
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D001897:Boronic Acids / Q000737:chemistry*; D004298:Dopamine / Q000302:isolation & purification*; D005453:Fluorescence; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry; D045663:Quantum Dots / Q000737:chemistry*; D019265:Spectroscopy, Near-Infrared
chemical_list: D001897:Boronic Acids; C028592:3-aminobenzeneboronic acid; D004298:Dopamine