title: Acute-Onset Endophthalmitis Caused by Alloiococcus otitidis following a Dexamethasone Intravitreal Implant.
abstract: OBJECTIVE
  To report the first case of acute endophthalmitis caused by Alloiococcus otitidis after a dexamethasone intravitreal implant.
  
  
  METHODS
  A 74-year-old female was treated with intravitreal Ozurdex(®) in her left eye for central retinal vein occlusion (CRVO). Best-corrected visual acuity (BCVA) in the eye was 4/20. Intravitreal injection was uneventful. At 48 h after injection, she developed ocular pain and visual acuity had dropped to light perception. Endophthalmitis associated with intravitreal injection was suspected.
  
  
  RESULTS
  The patient did not show a favorable clinical response following systemic, intravitreal, and topical fortified antibiotics. We then performed a vitreous biopsy and removed the Ozurdex implant by pars plana vitrectomy. A vitreous culture was positive for A. otitidis. At the 2-month follow up, no inflammation was observed, but due to CRVO and probably aggravated by endophthalmitis, the fundus showed macular fibrosis. The final BCVA was finger counting at 30 cm in her left eye.
  
  
  CONCLUSIONS
  In cases of an intravitreal implant associated with endophthalmitis, we recommend removal of the device because it may act as a permanent reservoir of organisms if it remains in the vitreous cavity.
authors.affiliation: Department of Ophthalmology, Santa Creu i Sant Pau Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.
authors.forename: Tizana
authors.initials: T
authors.lastname: Marchino
authors.forename: José I
authors.initials: JI
authors.lastname: Vela
authors.forename: Francisca
authors.initials: F
authors.lastname: Bassaganyas
authors.forename: Saskia
authors.initials: S
authors.lastname: Sánchez
authors.forename: José A
authors.initials: JA
authors.lastname: Buil
keywords: Alloiococcus otitidis; Dexamethasone implant; Endophthalmitis; Ozurdex