title: [Serum levels of vitamin D and chronic periodontitis in patients with chronic kidney disease].
abstract: BACKGROUND
  Concomitance of chronic periodontitis (CP) in patients with chronic kidney disease (CKD) have been associated with adverse outcomes. Vitamin D (25(OH)D) deficiency my play a role in CP and inadequate vitamin D status is common among patients with CKD.
  
  
  OBJECTIVE
  To examine the relationship between vitamin 25(OH)D and CP in patients with CKD not yet on dialysis.
  
  
  METHODS
  A case-control study was conducted. Cases and controls were defined as patients with CKD with and without CP, respectively. The demographic, clinical and laboratory data were obtained when the patient was attended in the outpatient clinic. CKD was defined and staged according to the NKF QDOKI TM. Serum 25(OH) D levels were measured by chemiluminescence when assessing the CP, which was definined according to the American Academy of Periodontoly (1999). Serum 25(OH)D levels were stratified into deficient (< 14 ηg/mL), insufficient (15-29 ηg/mL) and sufficiency (> 30 ηg/ mL).
  
  
  RESULTS
  A total of 15 cases were compared with 14 controls. Cases had lower median 25(OH)D levels than controls (22.6 versus 28.6 ηg/mL, p < 0.01) and were more likely to be categorized as vitamin D insufficiency/deficiency (93,3% versus 57,1%, p < 0,004). On the other hand, the percentage of controls with vitamin D sufficiency was higher then cases (42,9% versus 6,7%, p < 0,004).
  
  
  CONCLUSIONS
  In patients with CKD not yet on dialysis, vitamin D deficiency is associated with CP.
authors.affiliation: Center for Interdisciplinary Studies, Research and Nephrology Treatment. jessicabastos7@gmail.com
authors.forename: Jessica do Amaral
authors.initials: Jdo A
authors.lastname: Bastos
authors.forename: Luiz Carlos Ferreira de
authors.initials: LC
authors.lastname: Andrade
authors.forename: Ana Paula
authors.initials: AP
authors.lastname: Ferreira
authors.forename: Erica de Almeida
authors.initials: Ede A
authors.lastname: Barroso
authors.forename: Patrícia de Castro
authors.initials: Pde C
authors.lastname: Daibert
authors.forename: Patrícia Lima de Sá
authors.initials: PL
authors.lastname: Barreto
authors.forename: Eduardo Machado
authors.initials: EM
authors.lastname: Vilela
authors.forename: Andrea Marcia
authors.initials: AM
authors.lastname: Marcaccini
authors.forename: Fernando Antonio Basile
authors.initials: FA
authors.lastname: Colugnati
authors.forename: Marcus Gomes
authors.initials: MG
authors.lastname: Bastos
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D055113:Chronic Periodontitis / Q000097:blood* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D051436:Renal Insufficiency, Chronic / Q000097:blood* / Q000150:complications*; D014807:Vitamin D / Q000097:blood*; D014808:Vitamin D Deficiency / Q000097:blood* / Q000150:complications*
chemical_list: D014807:Vitamin D