title: Follow up after endoscopic resection in submucosal invasive colorectal cancers.
abstract: Submucosal invasive colorectal cancers (SM-CRC) have approximately a 10% chance of lymph node metastasis, which requires surgical resection including lymph node dissection for curative treatment. It is important to optimally survey patients after curative resection for SM-CRC in order to detect early recurrence. In the present report, we principally show the long-term outcomes after follow up of SM-CRC resected endoscopically based on a report of the literature and our experience in Japan. The long-term outcomes of low-risk SM-CRC endoscopically resected alone or high-risk SM-CRC with additional surgical resection with lymph node dissection are excellent. However, the risk of local recurrence of endoscopic resection alone in patients with high-risk submucosal invasive cancer was significantly higher in rectal cancer as compared to similar colonic cancer. Patients with submucosal rectal cancer showing high-risk pathological features are, therefore, strongly recommended to undergo additional treatment. We consider that longer follow up is required for patients with SM-CRC because recurrence occurred relatively later in SM-CRC compared to advanced colorectal cancer.
authors.affiliation: Department of Gastrointestinal Oncology and Endoscopy, National Cancer Center Hospital East, Kashiwa, Japan. hikemats@east.ncc.go.jp
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Ikematsu
authors.forename: Rajvinder
authors.initials: R
authors.lastname: Singh
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Yoda
authors.forename: Takahisa
authors.initials: T
authors.lastname: Matsuda
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Saito
mesh_terms: D003113:Colonoscopy / Q000379:methods*; D015179:Colorectal Neoplasms / Q000556:secondary / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology* / Q000601:surgery; D008207:Lymphatic Metastasis; D009361:Neoplasm Invasiveness; D017410:Practice Guidelines as Topic; D016896:Treatment Outcome