title: Comparison of haemodynamic effects of noninvasive ventilation delivered via ResQGARD and CPAP boussignac masks.
abstract: Noninvasive ventilation (NIV) is a technique of mechanical ventilation which does not require invasive airway management, i.e. intubation or tracheostomy. In emergency medicine Continuous Positive Airway Pressure (CPAP) is used often. A new method of NIV is Impedance Threshold Device (ITD). Breathing through an ITD is utilized to raise blood pressure in hypotensive patients.
  
  
  OBJECTIVE
  was to compare haemodynamic effects of NIV ITD and NIV CPAP.
  
  
  METHODS
  This study involved a group of 25 healthy volunteers. NIV was performed using ResQGARD ITD and CPAP Boussignac. Ventilation time was 25 minutes for each mask in each participant. Every three minutes parameters were collected: SpO2, BP and HR. There was a one hour interval in between ventilation with each mask. CPAP pressure was set at a level of 8 cm H2O and the mean inspiratory resistance of the ITD was 7cm H2O. Collected parameters were subjected to ANOVA statistical analysis.
  
  
  RESULTS
  Absolute comparison of BP, HR and SpO2 values did not reveal statistically significant differences between the masks. However considering blood pressure levels at entry, ventilation through an ITD significantly raised BP. Ventilation with NIV CPAP did not change significantly BP.
  
  
  CONCLUSIONS
  Ventilation through an ITD device significantly improve haemodynamic function, whereas CPAP ventilation had no significant effect on it.
authors.forename: Ewelina
authors.initials: E
authors.lastname: Gaszyńska
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Roguszka
authors.forename: Michał
authors.initials: M
authors.lastname: Stankiewicz-Rudnicki
authors.forename: Andrzej
authors.initials: A
authors.lastname: Wieczorek
authors.forename: Tomasz
authors.initials: T
authors.lastname: Gaszyński
mesh_terms: D000328:Adult; D045422:Continuous Positive Airway Pressure / Q000379:methods*; D005260:Female; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007022:Hypotension / Q000628:therapy*; D008297:Male; D008397:Masks; D008875:Middle Aged; D063087:Noninvasive Ventilation / Q000379:methods*; D012016:Reference Values