title: [Metabolic syndrome prevalence in Chilean children and adolescent with family history of chronic noncommunicable diseases].
abstract: Family history (FH+) of non transmisible chronic diseases (NTCD) increase MetS risk. In Chile, the MetS affects 27% of overweight children, and fasting hyperglycemia is very low prevalent (4,0%). The objective was to study the prevalence of MetS and the cardiovascular risk factors (CVRF) in overweight children with a family background of NTCD and analyze its association with the number of relatives witth NTCD and with parental history (PH). In 183 overweight children (BMI > or = p85) mean age 11,8 +/- 1,8 (86 males) with a FH+ (parental or grandparental) of NTCD, were assessed the BMI z (CDC / NCHS), waist circumference, blood arterial pressure, fasting Glucose and Insulin (RIA), triglycerides, HDL chol. The MetS and the CVRF were diagnosed using the Cook phenotype and the insulin resistance (IR) through the HOMA-IR. Chi2, ANOVA, t Student and Willcoxon test were performed. The frequency of FH+ of DM2, hypertension and dyslipidemia were 81,4%, 88,0% and 71,6 % respectively. The MeTS prevalence was 46,5 % associated to overweight magnitude an parental history of NTCD. The prevalence of hypertriglyceridemia was 54,6%, while fasting hyperglycemia affected 31,4% of the sample. There was no association between number of relatives with NTCD and CV risk profile. We conclude that in overweight children with FH+ of NTCD, the prevalence of MetS, dyslipidemia and fasting hyperglycemia are significantly higher, than those observed in the general population of obese children.
authors.affiliation: Instituto de Nutrición y Tecnología de los Alimentos (INTA), Departamento de Nutrición y Escuela de Nutrición y Dietética y de la Facultad de Medicina, Universidad de Chile, Santiago, Chile.
authors.forename: Raquel
authors.initials: R
authors.lastname: Burrows
authors.forename: Eduardo
authors.initials: E
authors.lastname: Atalah
authors.forename: Laura
authors.initials: L
authors.lastname: Leiva
authors.forename: Pamela
authors.initials: P
authors.lastname: Rojas
authors.forename: María Pía de la
authors.initials: MP
authors.lastname: Maza
authors.forename: Fabian
authors.initials: F
authors.lastname: Vásquez
authors.forename: Lydia
authors.initials: L
authors.lastname: Lera
authors.forename: Erick
authors.initials: E
authors.lastname: Díaz
mesh_terms: D000293:Adolescent; D001786:Blood Glucose / Q000032:analysis; D002318:Cardiovascular Diseases / Q000235:genetics*; D002648:Child; D002677:Chile / Q000453:epidemiology; D002784:Cholesterol / Q000097:blood; D002908:Chronic Disease; D048909:Diabetes Complications; D004198:Disease Susceptibility; D050171:Dyslipidemias / Q000453:epidemiology; D005190:Family; D005260:Female; D006801:Humans; D007003:Hypoglycemia / Q000453:epidemiology*; D007333:Insulin Resistance / Q000502:physiology; D008297:Male; D008487:Medical History Taking; D024821:Metabolic Syndrome / Q000453:epidemiology*; D050177:Overweight / Q000150:complications; D015995:Prevalence; D012307:Risk Factors
chemical_list: D001786:Blood Glucose; D002784:Cholesterol