title: Increased 99mTc TRODAT-1 uptake in anaplastic oligodendroglioma.
abstract: (99m)Tc TRODAT-1, a selective dopamine transporter SPECT imaging agent, has demonstrated its efficacy in identifying patients with Parkinson disease. Primary or metastatic brain neoplasm uptake of TRODAT-1 is rarely reported in literatures. A 51-year-old female patient underwent TRODAT-1 study for bradykinesia and altered cognitive function; the images showed abnormal extrastriatal uptake in the right frontal lobe subsequent to operation, and pathological examination confirmed anaplastic oligodendroglioma. Care should be taken in interpreting TRODAT-1 image; any focus on abnormal accumulation of radiotracer should not be overlooked because it can be brain neoplasm as demonstrated in this case.
authors.affiliation: From the *Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, †Graduate Institute of Clinical Medicine Science, ‡Department of Biomedical Imaging and Radiological Science, and §School of Medicine, China Medical University, Taichung, Taiwan.
authors.forename: Yu-Ren
authors.initials: YR
authors.lastname: Chen
authors.forename: Te-Chun
authors.initials: TC
authors.lastname: Hsieh
authors.forename: Kuo-Yang
authors.initials: KY
authors.lastname: Yen
authors.forename: Chia-Hung
authors.initials: CH
authors.lastname: Kao
mesh_terms: D001692:Biological Transport; D005260:Female; D006801:Humans; D008875:Middle Aged; D009837:Oligodendroglioma / Q000000981:diagnostic imaging / Q000378:metabolism*; D015609:Organotechnetium Compounds / Q000378:metabolism*; D015899:Tomography, Emission-Computed, Single-Photon; D014326:Tropanes / Q000378:metabolism*
chemical_list: D015609:Organotechnetium Compounds; D014326:Tropanes; C104196:technetium Tc 99m TRODAT-1