title: Surgery-induced changes and early recovery of hip-muscle strength, leg-press power, and functional performance after fast-track total hip arthroplasty: a prospective cohort study.
abstract: BACKGROUND
  By measuring very early changes in muscle strength and functional performance after fast-track total hip arthroplasty (THA), post-operative rehabilitation, introduced soon after surgery, can be designed to specifically target identified deficits.
  
  
  OBJECTIVE
  Firstly, to quantify changes (compared to pre-operative values) in hip muscle strength, leg-press power, and functional performance in the first week after THA, and secondly, to explore relationships between the muscle strength changes, and changes in hip pain, systemic inflammation, and thigh swelling.
  
  
  METHODS
  Prospective, cohort study.
  
  
  METHODS
  Convenience sample of patients receiving a THA at Copenhagen University Hospital, Hvidovre, Denmark, between March and December 2011.
  
  
  METHODS
  Thirty-five patients (65.9 ± 7.2 years) undergoing THA.
  
  
  METHODS
  Hip muscle strength, leg-press power, performance-based function, and self-reported disability were determined prior to, and 2 and 8 days after, THA (Day 2 and 8, respectively). Hip pain, thigh swelling, and C-Reactive Protein were also determined.
  
  
  RESULTS
  Five patients were lost to follow-up. Hip muscle strength and leg press power were substantially reduced at Day 2 (range of reductions: 41-58%, P<0.001), but less pronounced at Day 8 (range of reductions: 23-31%, P<0.017). Self-reported symptoms and function (HOOS: Pain, Symptoms, and ADL) improved at Day 8 (P<0.014). Changes in hip pain, C-Reactive Protein, and thigh swelling were not related to the muscle strength and power losses.
  
  
  CONCLUSIONS
  Hip muscle strength and leg-press power decreased substantially in the first week after THA - especially at Day 2 - with some recovery at Day 8. The muscle strength loss and power loss were not related to changes in hip pain, systemic inflammation, or thigh swelling. In contrast, self-reported symptoms and function improved. These data on surgery-induced changes in muscle strength may help design impairment-directed, post-operative rehabilitation to be introduced soon after surgery.
  
  
  BACKGROUND
  ClinicalTrials.gov NCT01246674.
authors.affiliation: The Lundbeck Centre for Fast-track Hip and Knee Arthroplasty, Copenhagen University Hospital, Hvidovre, Denmark.
authors.forename: Bente
authors.initials: B
authors.lastname: Holm
authors.forename: Kristian
authors.initials: K
authors.lastname: Thorborg
authors.forename: Henrik
authors.initials: H
authors.lastname: Husted
authors.forename: Henrik
authors.initials: H
authors.lastname: Kehlet
authors.forename: Thomas
authors.initials: T
authors.lastname: Bandholm
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D005260:Female; D006801:Humans; D035002:Lower Extremity / Q000601:surgery; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology*; D011446:Prospective Studies