title: Molecular epidemiology of avian bornavirus from pet birds in Japan.
abstract: Recently, Avian bornavirus (ABV) was detected in proventricular dilatation disease (PDD) affected-birds and feather picking diseases affected-birds. However, the pathogenicity of ABV has not been thoroughly investigated. In this study, we surveyed ABV in pet birds in Japan. We found four ABV-infected birds among 93 pet birds using RT-PCR, and genotypes of the ABV were determined as ABV-2 and -4. Two of the birds positive for ABV-4 showed proventricular dilatation typically found in PDD, and chronic stomach disturbance, whereas two of the birds positive for ABV-2 showed unexplained behavioral problems that are tapping, autophagia, and cloaca prolapse.
authors.affiliation: Research and Education Center for Prevention of Global Infectious Diseases of Animals, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo 183-8509, Japan.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Sassa
authors.forename: Masayuki
authors.initials: M
authors.lastname: Horie
authors.forename: Kan
authors.initials: K
authors.lastname: Fujino
authors.forename: Naomi
authors.initials: N
authors.lastname: Nishiura
authors.forename: Sachiko
authors.initials: S
authors.lastname: Okazaki
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Furuya
authors.forename: Makoto
authors.initials: M
authors.lastname: Nagai
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Omatsu
authors.forename: Atsushi
authors.initials: A
authors.lastname: Kojima
authors.forename: Masaya
authors.initials: M
authors.lastname: Mizugami
authors.forename: Kengo
authors.initials: K
authors.lastname: Ueda
authors.forename: Haruko
authors.initials: H
authors.lastname: Iki
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Ebisawa
authors.forename: Keizo
authors.initials: K
authors.lastname: Tomonaga
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Mizutani
mesh_terms: D000818:Animals; D001715:Bird Diseases / Q000821:virology*; D028981:Bornaviridae / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D005838:Genotype; D007564:Japan / Q000453:epidemiology; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D018701:Mononegavirales Infections / Q000662:veterinary* / Q000821:virology; D057805:Pets / Q000821:virology*; D010802:Phylogeny