title: Two new tigliane diterpene esters from the flower buds of Daphne genkwa.
abstract: The phytochemical investigation of the flower buds of Daphne genkwa yielded four highly oxygenated tigliane diterpene esters (1-4), including two new phorbol derivatives, 12-O-(2'E,4'E-decadienoyl)-7-oxo-5-ene-phorbol-13-acetate (1) and 12-O-neodecanoyl-7-oxo-5-ene-phorbol-13-acetate (2). The molecular structures of the isolated compounds were elucidated on the basis of extensive spectroscopic analysis, including 1D and 2D NMR.
authors.affiliation: Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China.
authors.forename: Rui
authors.initials: R
authors.lastname: Wang
authors.forename: Jian-Yong
authors.initials: JY
authors.lastname: Li
authors.forename: Huan-Yang
authors.initials: HY
authors.lastname: Qi
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Shi
mesh_terms: D032364:Daphne / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000302:isolation & purification*; D004952:Esters; D035264:Flowers / Q000737:chemistry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010704:Phorbols / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: C582532:12-O-(2'E,4'E-decadienoyl)-7-oxo-5-ene-phorbol-13-acetate; C582533:12-O-neodecanoyl-7-oxo-5-ene-phorbol-13-acetate; D004224:Diterpenes; D004365:Drugs, Chinese Herbal; D004952:Esters; D010704:Phorbols; C033085:phorbol