title: (99m)Tc-MAG3 diuretic renography in diagnosis of obstructive nephropathy in adults: a comparison between F-15 and a new procedure F+10(sp) in seated position.
abstract: OBJECTIVE
  The objective of this study was to compare 2 diuretic renography procedures: F-15 versus F+10(sp) for diagnosis of obstructive uropathy in adults.
  
  
  METHODS
  Thirty-six patients with unilateral or bilateral hydronephrosis had 2 consecutive Tc-MAG3 diuretic renograms within 7 days, using the widely used procedure F-15 in supine position, and a new seated-position procedure whereby the patient drinks 400 to 500 mL of water at 5 minutes and receives an injection of 20 mg of furosemide at 10 minutes [F+10 (sp)].
  
  
  RESULTS
  F-15 showed nonobstructive results in 63.9% of kidneys, obstruction in 26.4%, and equivocal findings in 6.9% and was not applicable in 2.8%. F+10(sp) showed nonobstructive results in 70.9%, obstruction in 27.8%, and equivocal result in 1.4% of kidneys. Nephroptosis was observed by F+10(sp) in 22.2% of kidneys. Adverse effects reported for the F-15 were hypotension in 2 patients, renal colic in 3 patients, and interruption due to voiding in 5 patients. No adverse effects were reported for F+10(sp).
  
  
  CONCLUSIONS
  This study shows that the F+10(sp) procedure reduces the equivocal findings of F-15 procedure in 36 patients. It can improve the accuracy and compliance, avoiding adverse effects and reducing bladder filling-related problems.
authors.affiliation: Department of Nuclear Medicine, Cristo Re Hospital, Rome, Italy.
authors.forename: Girolamo
authors.initials: G
authors.lastname: Tartaglione
authors.forename: Alessandro
authors.initials: A
authors.lastname: D'Addessi
authors.forename: Chiara
authors.initials: C
authors.lastname: De Waure
authors.forename: Marco
authors.initials: M
authors.lastname: Pagan
authors.forename: Marco
authors.initials: M
authors.lastname: Raccioppi
authors.forename: Emilio
authors.initials: E
authors.lastname: Sacco
authors.forename: Chiara
authors.initials: C
authors.lastname: Cadeddu
authors.forename: Matteo
authors.initials: M
authors.lastname: Vittori
authors.forename: Pier Francesco
authors.initials: PF
authors.lastname: Bassi
authors.forename: Alice
authors.initials: A
authors.lastname: Ferretti
authors.forename: Adil
authors.initials: A
authors.lastname: Al-Nahhas
authors.forename: Domenico
authors.initials: D
authors.lastname: Rubello
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003710:Demography; D004232:Diuretics; D005260:Female; D005665:Furosemide; D006801:Humans; D006869:Hydronephrosis / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011187:Posture; D011866:Radioisotope Renography; D017263:Technetium Tc 99m Mertiatide; D055815:Young Adult
chemical_list: D004232:Diuretics; D017263:Technetium Tc 99m Mertiatide; D005665:Furosemide