title: A Case of Bilateral Descemet's Membrane and Subepithelial Opacity: In vivo Laser Confocal Microscopic Study.
abstract: OBJECTIVE
  To report the in vivo laser confocal microscopy findings from a patient with Descemet's membrane and subepithelial opacity OU.
  
  
  METHODS
  A healthy 41-year-old male with Descemet's membrane and subepithelial opacity OU was studied. Routine ophthalmic examination, standard slit-lamp biomicroscopy, and in vivo laser confocal microscopic analysis of the entire corneal layer were performed. Slit-lamp biomicroscopy revealed subepithelial opacity in the mid-peripheral to peripheral cornea and numerous opacities located at the level of Descemet's membrane. It was difficult to distinguish the precise histological location of the opacity. In vivo laser confocal microscopy showed numerous hyperreflective particles in the subepithelium to superficial stroma and hyperreflectivity of Descemet's membrane. No abnormalities could be detected in the epithelial cell layer, midstromal layer, deep stromal layer, or endothelial cell layer.
  
  
  CONCLUSIONS
  Although the origin of the corneal opacities was unclear, in vivo laser confocal microscopy was useful for observing microstructural abnormalities in a case of Descemet's membrane and subepithelial opacity.
authors.affiliation: Department of Ophthalmology, Kanazawa University Graduate School of Medical Science, Kanazawa, Toyama, Japan.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Hatta
authors.forename: Hideaki
authors.initials: H
authors.lastname: Yokogawa
authors.forename: Akira
authors.initials: A
authors.lastname: Kobayashi
authors.forename: Makoto
authors.initials: M
authors.lastname: Torisaki
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Sugiyama
keywords: Confocal microscopy; Descemet's membrane opacity; Subepithelial opacity