title: Candida species lens abscesses in infants with a history of neonatal Candida sepsis.
abstract: We report 3 patients who were delivered prematurely and who developed a lens opacity with signs of ocular inflammation at a postgestational age of 10-52 weeks. All patients had been treated for Candida sepsis as neonates. Each patient underwent lensectomy and anterior vitrectomy. In 2 infants Candida albicans was cultured from the lens/anterior chamber membrane; in 1 Candida parapsilosis was cultured from a lens aspirate. Despite eradication of the fungal infection, outcomes were poor: 2 eyes developed glaucoma, and 1 developed a retinal detachment with subsequent phthisis.
authors.affiliation: Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA. cousernl@gmail.com
authors.forename: Natario L
authors.initials: NL
authors.lastname: Couser
authors.forename: G Baker
authors.initials: GB
authors.lastname: Hubbard
authors.forename: Lyndon B
authors.initials: LB
authors.lastname: Lee
authors.forename: Amy K
authors.initials: AK
authors.lastname: Hutchinson
authors.forename: Scott R
authors.initials: SR
authors.lastname: Lambert
mesh_terms: D002175:Candida / Q000302:isolation & purification*; D058387:Candidemia / Q000150:complications*; D002386:Cataract / Q000382:microbiology; D015821:Eye Infections, Fungal / Q000382:microbiology*; D005260:Female; D006801:Humans; D007223:Infant; D007905:Lens Diseases / Q000382:microbiology*; D008297:Male