title: Impact of bariatric surgery on quality of life, functional capacity, and symptoms in patients with heart failure.
abstract: Obesity is a risk factor for heart failure (HF), but the benefit of weight loss in HF is unknown. We assessed the effects of bariatric surgery (BSx) compared to non-operative treatment for morbid obesity on overall quality of life (QoL), functional capacity, and symptoms in 13 HF patients undergoing BSx and six HF patients treated without surgery. In the BSx group, median age was 62, body mass index (BMI) was 55 kg/m(2), and 5/13 were males; in the non-operative group, median age was 69, BMI was 42 kg/m(2), and 1/6 were male. Median follow-up was 4.3 and 2.7 years, respectively. At follow-up, BMI was less in the BSx group (35 vs 47 kg/m(2), p < 0.001); QoL (p < 0.01), frequency of exertional dyspnea (p = 0.01), and leg edema (p = 0.04) improved only in the BSx group. BSx induced weight loss and improved QoL and symptoms in morbidly obese patients with HF.
authors.affiliation: Division of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.
authors.forename: William R
authors.initials: WR
authors.lastname: Miranda
authors.forename: John A
authors.initials: JA
authors.lastname: Batsis
authors.forename: Michael G
authors.initials: MG
authors.lastname: Sarr
authors.forename: Maria L
authors.initials: ML
authors.lastname: Collazo-Clavell
authors.forename: Matthew M
authors.initials: MM
authors.lastname: Clark
authors.forename: Virend K
authors.initials: VK
authors.lastname: Somers
authors.forename: Francisco
authors.initials: F
authors.lastname: Lopez-Jimenez
mesh_terms: D015992:Body Mass Index; D018450:Disease Progression; D004417:Dyspnea / Q000209:etiology / Q000517:prevention & control; D004487:Edema / Q000209:etiology / Q000517:prevention & control; D005260:Female; D005500:Follow-Up Studies; D015391:Gastroplasty / Q000379:methods; D006333:Heart Failure / Q000209:etiology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications / Q000503:physiopathology* / Q000601:surgery; D011788:Quality of Life; D012307:Risk Factors; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014481:United States; D015431:Weight Loss