title: Carbolithiation of meso-aryl-substituted 5,15-diazaporphyrin selectively provides 3-alkylated diazachlorins.
abstract: Treatment of meso-mesityl 5,15-diazaporphyrin with alkyllithiums in toluene at low temperature provided monoalkylated diazachlorins through highly regioselective nucleophilic addition at the β-position near the meso-nitrogen atom.
authors.affiliation: Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan.
authors.forename: Ayaka
authors.initials: A
authors.lastname: Yamaji
authors.forename: Satoru
authors.initials: S
authors.lastname: Hiroto
authors.forename: Ji-Young
authors.initials: JY
authors.lastname: Shin
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Shinokubo
mesh_terms: D000478:Alkylation; D008094:Lithium / Q000737:chemistry; D009584:Nitrogen / Q000737:chemistry; D011166:Porphyrins / Q000138:chemical synthesis / Q000737:chemistry*; D011789:Quantum Theory; D013237:Stereoisomerism; D013696:Temperature; D014050:Toluene / Q000737:chemistry
chemical_list: D011166:Porphyrins; C006969:chlorin; D014050:Toluene; D008094:Lithium; D009584:Nitrogen