title: Uremic cardiomyopathy: an underdiagnosed disease.
abstract: Uremic cardiomyopathy is responsible for high morbidity and mortality rates among patients with chronic kidney disease (CKD) or end-stage renal disease (ESRD); however, the early implementation of hemodialysis may halt its progression. Nonconventional hemodialysis, such as frequent hemodialysis, appears to have an advantage over conventional hemodialysis. Kidney transplantation has been shown to reverse uremic cardiomyopathy and to confer a significant survival advantage over hemodialysis. Targeting future therapies at the underlying cellular mechanisms of uremic cardiomyopathy may finally start to reduce the burden of uremic cardiomyopathy in the CKD and ESRD population.
authors.affiliation: Department of Cardiology, UMDNJ, New Jersey Medical School, Newark, NJ 07103, USA. Eyadalhaj@yahoo.com
authors.forename: Eyad
authors.initials: E
authors.lastname: Alhaj
authors.forename: Nehad
authors.initials: N
authors.lastname: Alhaj
authors.forename: Ifad
authors.initials: I
authors.lastname: Rahman
authors.forename: Tariq O
authors.initials: TO
authors.lastname: Niazi
authors.forename: Robert
authors.initials: R
authors.lastname: Berkowitz
authors.forename: Marc
authors.initials: M
authors.lastname: Klapholz
mesh_terms: D009202:Cardiomyopathies / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging / Q000379:methods*; D018450:Disease Progression; D014943:Global Health; D006801:Humans; D009017:Morbidity; D014511:Uremia / Q000150:complications* / Q000175:diagnosis