title: Cardiac FDG-PET to assess sarcoidosis in a cardiac allograft.
abstract: A 58-year-old man with end-stage heart failure caused by cardiac sarcoidosis underwent an orthotopic heart transplant. His immediate posttransplant course was uncomplicated, but several months later, an endomyocardial biopsy revealed likely recurrent sarcoidosis. A cardiac F-FDG PET study subsequently showed focal anteroseptal uptake that suggested the presence of inflammation. Despite steroid therapy, a study repeated 3 months later showed persistent anteroseptal FDG uptake and new hypokinesis in that region. After escalating his steroid therapy, a final FDG-PET study ultimately demonstrated resolution of the uptake and normalization of anteroseptal wall motion.
authors.affiliation: From the Section of Cardiovascular Medicine, Yale University, New Haven, CT.
authors.forename: Andrew
authors.initials: A
authors.lastname: Chen
authors.forename: Pravien
authors.initials: P
authors.lastname: Khanna
authors.forename: Alexa
authors.initials: A
authors.lastname: Siddon
authors.forename: Raymond
authors.initials: R
authors.lastname: Russell
mesh_terms: D064591:Allografts; D019788:Fluorodeoxyglucose F18; D006321:Heart / Q000000981:diagnostic imaging*; D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012507:Sarcoidosis / Q000000981:diagnostic imaging* / Q000209:etiology*
chemical_list: D019788:Fluorodeoxyglucose F18