title: [Active surveillance: concept for renal cell carcinoma?].
abstract: More than 80% of renal cell carcinomas are currently being detected incidentally by ultrasonic imaging and often affect elderly patients with substantial comorbidities. Surgical options cannot be applied in this cohort as routinely as in younger patients, as in some cases the perioperative risk factors may outweigh the risk of tumor-related death. In this context the concept of active surveillance for localized renal cell cancer in elderly patients is becoming increasingly important. The aim of active surveillance is to avoid surgery-related adverse effects and to achieve a controlled observation of tumor behavior with an option of delayed intervention in cases of aggressive clinical tumor features. This review sheds light on the current status of this strategy.
authors.affiliation: Klinik für Urologie und Kinderurologie, Universitätsklinikum Frankfurt, Goethe-Universität, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Deutschland. igor.tsaur@kgu.de
authors.forename: I
authors.initials: I
authors.lastname: Tsaur
authors.forename: D
authors.initials: D
authors.lastname: Schilling
authors.forename: A
authors.initials: A
authors.lastname: Haferkamp
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000175:diagnosis* / Q000628:therapy*; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D015577:Geriatric Assessment / Q000379:methods*; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000009:adverse effects*; D011159:Population Surveillance / Q000379:methods*; D018570:Risk Assessment