title: [Study on the dynamic variations of Z-ligustilide and n-butylidenephthalide content in essential oil of radix angelicae sinensis from different growth period].
abstract: OBJECTIVE
  To study the variation of the biomass of the root and active components of Angelica sinensis during different growth periods.
  
  
  METHODS
  27 batches of Angelica sinensis were harvested from different growth periods, and the biomass of underground parts were determined; The Gas Chromatography-Mass Spectrometry (GC-MS) was used for determining the contents of Z-ligustilide and n-Butylidenephthalide in essential oil of Radix Angelicae Sinensis.
  
  
  RESULTS
  The average contents of n-Butylidenephthalide and Z-ligustilide were more than 1% and 40% in the total essential oil of Radix Angelicae sinensis respectively. Their contents showed larger difference during different growth period.
  
  
  CONCLUSIONS
  The contents of Z-ligustilide and n-Butylidenephthalide of Radix Angelicae Sinensis is closely related to their growth period.
authors.affiliation: Gansu College of Traditional Chinese Medicine, Lanzhou 730000, China. sarinasarula@163.com
authors.forename: Ri-Na
authors.initials: RN
authors.lastname: Sa
authors.forename: Ya-Li
authors.initials: YL
authors.lastname: Wang
authors.forename: Shu-Qiang
authors.initials: SQ
authors.lastname: Zhu
authors.forename: Xin-Bo
authors.initials: XB
authors.lastname: Pan
authors.forename: Ying-Wen
authors.initials: YW
authors.lastname: Yang
authors.forename: Yu-Jing
authors.initials: YJ
authors.lastname: Sun
mesh_terms: D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000032:analysis; D029971:Angelica sinensis / Q000737:chemistry* / Q000254:growth & development; D018533:Biomass; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D009822:Oils, Volatile / Q000032:analysis* / Q000737:chemistry; D010796:Phthalic Anhydrides / Q000032:analysis*; D018517:Plant Roots / Q000737:chemistry / Q000254:growth & development; D010946:Plants, Medicinal / Q000737:chemistry / Q000254:growth & development; D012621:Seasons
chemical_list: D009822:Oils, Volatile; D010796:Phthalic Anhydrides; C027820:ligustilide; D015107:4-Butyrolactone; C026105:butylidenephthalide