title: The design, synthesis and validation of recoverable and readily reusable siloxane transfer agents for Pd-catalyzed cross-coupling reactions.
abstract: The development of competent, recoverable and reusable 1-oxa-2-silacyclopentene (siloxane) transfer agents for Pd-catalyzed cross-coupling reactions (CCRs) of organolithium reagents with aryl and alkenyl iodides has been achieved. Drawbacks of the first-generation siloxane-transfer agent (1), relating to facile recovery for potential recycling, have been addressed.
authors.affiliation: Department of Chemistry, University of Pennsylvania , Philadelphia, Pennsylvania 19104, United States.
authors.forename: Dionicio
authors.initials: D
authors.lastname: Martinez-Solorio
authors.forename: Adam T
authors.initials: AT
authors.lastname: Hoye
authors.forename: Minh H
authors.initials: MH
authors.lastname: Nguyen
authors.forename: Amos B
authors.initials: AB
authors.lastname: Smith
mesh_terms: D002384:Catalysis; D003432:Cross-Linking Reagents / Q000737:chemistry*; D008094:Lithium / Q000737:chemistry; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry; D012833:Siloxanes / Q000138:chemical synthesis* / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D003432:Cross-Linking Reagents; D012833:Siloxanes; D010165:Palladium; D008094:Lithium