title: [Reversible cerebral vasoconstriction syndrome in a stroke patient with systemic lupus erythematosus and antiphospholipid antibody].
abstract: A 36-year-old female with systemic lupus erythematosus and antiphospholipid syndrome was referred to our department because of mild weakness of left arm and an episode of right amaurosis fugax for twenty days. Brain MRI showed right ACA/MCA/PCA border zone infarction on DWI/T2WI/FLAIR and MR angiography (MRA) showed multiple segmental stenosis in right internal carotid artery, right and left middle cerebral artery, and bilateral posterior cerebral arteries. Treatment with oral aspirin (100 mg/day) and continuous infusion of heparin kept her neurological symptoms and signs stable. MRA on 28 days revealed complete recovery of multiple stenotic lesions, thus, diagnosis of reversible cerebral vasoconstriction (RCVS) was made. RCVS should be considered as a cause of neurological deficit in patients with SLE regardless of thunderclap headache.
authors.affiliation: Division of Neurology, Kobe University Graduate School of Medicine.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Uenaka
authors.forename: Hirotoshi
authors.initials: H
authors.lastname: Hamaguchi
authors.forename: Kenji
authors.initials: K
authors.lastname: Sekiguchi
authors.forename: Hisatomo
authors.initials: H
authors.lastname: Kowa
authors.forename: Fumio
authors.initials: F
authors.lastname: Kanda
authors.forename: Tatsushi
authors.initials: T
authors.lastname: Toda
mesh_terms: D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000032:analysis*; D002561:Cerebrovascular Disorders / Q000209:etiology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D020521:Stroke / Q000150:complications*; D014661:Vasoconstriction
chemical_list: D017152:Antibodies, Antiphospholipid