title: Direct electron transfer of Cytochrome c at mono-dispersed and negatively charged perylene-graphene matrix.
abstract: Mono-dispersed 3,4,9,10-perylene tetracarboxylic acid (PTCA) functionalized graphene sheets (PTCA-graphene) were fabricated by a chemical route and dispersed well in aqueous solution. PTCA-graphene with plenty of -COOH groups as electrostatic absorbing sites were beneficial to the loading of Cytochrome c (Cyt c). Cyt c, which was tightly immobilized on the PTCA-graphene modified glassy carbon electrode, maintained its natural conformation. Direct electron transfer of Cyt c and the electro-catalytic activity towards the reduction of H2O2 were also achieved. It has been substantiated that PTCA-graphene is a preferable biocompatible matrix for Cyt c.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, c/o Engineering Laboratory for Modern Analytical Techniques, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China.
authors.forename: Nan
authors.initials: N
authors.lastname: Zhang
authors.forename: Xiangyu
authors.initials: X
authors.lastname: Lv
authors.forename: Weiguang
authors.initials: W
authors.lastname: Ma
authors.forename: Yuwei
authors.initials: Y
authors.lastname: Hu
authors.forename: Fenghua
authors.initials: F
authors.lastname: Li
authors.forename: Dongxue
authors.initials: D
authors.lastname: Han
authors.forename: Li
authors.initials: L
authors.lastname: Niu
mesh_terms: D000818:Animals; D045304:Cytochromes c / Q000737:chemistry* / Q000378:metabolism; D055664:Electrochemical Techniques; D004579:Electron Transport; D004800:Enzymes, Immobilized / Q000737:chemistry* / Q000378:metabolism; D006108:Graphite / Q000737:chemistry*; D006736:Horses; D006861:Hydrogen Peroxide / Q000378:metabolism; D010084:Oxidation-Reduction; D010569:Perylene / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: C560550:3,4,9,10-perylene tetracarboxylic acid; D004800:Enzymes, Immobilized; D010569:Perylene; D006108:Graphite; D045304:Cytochromes c; D006861:Hydrogen Peroxide