title: Identification of multiple novel viruses, including a parvovirus and a hepevirus, in feces of red foxes.
abstract: Red foxes (Vulpes vulpes) are the most widespread members of the order of Carnivora. Since they often live in (peri)urban areas, they are a potential reservoir of viruses that transmit from wildlife to humans or domestic animals. Here we evaluated the fecal viral microbiome of 13 red foxes by random PCR in combination with next-generation sequencing. Various novel viruses, including a parvovirus, bocavirus, adeno-associated virus, hepevirus, astroviruses, and picobirnaviruses, were identified.
authors.affiliation: Department of Viroscience, Erasmus Medical Centre, Rotterdam, The Netherlands. r.bodewes@erasmusmc.nl
authors.forename: Rogier
authors.initials: R
authors.lastname: Bodewes
authors.forename: Joke
authors.initials: J
authors.lastname: van der Giessen
authors.forename: Bart L
authors.initials: BL
authors.lastname: Haagmans
authors.forename: Albert D M E
authors.initials: AD
authors.lastname: Osterhaus
authors.forename: Saskia L
authors.initials: SL
authors.lastname: Smits
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D019200:Astroviridae / Q000235:genetics; D001483:Base Sequence; D004197:Disease Reservoirs / Q000662:veterinary* / Q000821:virology; D005243:Feces / Q000821:virology*; D005589:Foxes / Q000821:virology*; D052678:Hepevirus / Q000235:genetics*; D016013:Likelihood Functions; D054892:Metagenome / Q000235:genetics*; D008957:Models, Genetic; D008969:Molecular Sequence Data; D017992:Parvovirus / Q000235:genetics*; D010802:Phylogeny; D018708:Picobirnavirus / Q000235:genetics; D016133:Polymerase Chain Reaction / Q000662:veterinary; D017422:Sequence Analysis, DNA; D013045:Species Specificity