title: Thoracic phosphaturic mesenchymal tumors causing oncogenic osteomalacia.
abstract: Oncogenic osteomalacia is a rare paraneoplastic syndrome induced by mesenchymal tumors. Just over 100 cases have been reported for this rare disorder, and only seven instances were caused by phosphaturic mesenchymal tumors of the spine. The authors present an illustrative case of a 61-year-old woman with oncogenic osteomalacia induced by a tumor of the spine, and review the literature describing the clinical presentation, surgical treatment, and follow-up of this syndrome.
authors.affiliation: Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Puthenveetil
authors.forename: Eyas M
authors.initials: EM
authors.lastname: Hattab
authors.forename: Munro
authors.initials: M
authors.lastname: Peacock
authors.forename: Eric M
authors.initials: EM
authors.lastname: Horn
mesh_terms: D005260:Female; D005346:Fibroblast Growth Factors / Q000378:metabolism; D006801:Humans; D007015:Hypophosphatemia, Familial / Q000150:complications* / Q000188:drug therapy; D008637:Mesenchymoma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D009372:Neoplasms, Connective Tissue / Q000473:pathology* / Q000601:surgery; D019637:Orthopedic Procedures / Q000379:methods; D010018:Osteomalacia; D010257:Paraneoplastic Syndromes / Q000473:pathology* / Q000601:surgery; D013125:Spinal Neoplasms / Q000473:pathology* / Q000601:surgery; D013904:Thoracic Vertebrae / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome
chemical_list: D005346:Fibroblast Growth Factors
keywords: Fibroblast growth factor; Hypophosphatemia; Oncogenic osteomalacia; Paraneoplastic syndrome; Phosphaturic mesenchymal tumor; Thoracic spine