title: Treatment of gastric MALT lymphoma with a focus on Helicobacter pylori eradication.
abstract: Mucosa-associated lymphoid tissue (MALT) lymphoma is an indolent disease with a prolonged clinical course that most often involves the stomach. Clinically, for Helicobacter pylori-positive low-grade MALT lymphoma, antibiotics have been used as the first-line treatment. The recommended anti-Helicobacter triple drug therapy includes a proton pump inhibitor (or ranitidine bismuth citrate), clarithromycin, and amoxicillin (or metronidazole). Considering the difficulty involved with confirming histological remission and the lack of systemic endoscopic follow-up, much work remains to be done in this area. This review describes MALT lymphoma treatment methods and their efficacy, highlights results of the newest studies, and proposes avenues toward future developments in this field.
authors.affiliation: Department of Hematology and Blood and Marrow Transplantation, Tianjin Medical University Cancer Institute and Hospital, Tianjin Key Laboratory of Cancer Prevention and Therapy, Huan-Hu-Xi Road, Ti-Yuan-Bei, He Xi District, Tianjin, People's Republic of China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Guo
authors.forename: Shanqi
authors.initials: S
authors.lastname: Guo
authors.forename: Yizhuo
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D016481:Helicobacter Infections / Q000150:complications* / Q000188:drug therapy*; D016480:Helicobacter pylori / Q000187:drug effects; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications* / Q000473:pathology / Q000628:therapy*; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy*; D016896:Treatment Outcome