title: Early application of an intra-aortic balloon pump in patients with ST-segment elevation acute myocardial infarction scheduled for elective percutaneous coronary intervention.
abstract: OBJECTIVE
  This study evaluated the effect of early application of intra-aortic balloon pump (IABP) counterpulsation in patients with ST-segment elevation acute myocardial infarction (STEMI), scheduled for elective percutaneous coronary intervention (PCI).
  
  
  METHODS
  Patients who had experienced STEMI for 12-72 h received (IABP group) or did not receive (control group) IABP counterpulsation for 3-5 days before PCI.
  
  
  RESULTS
  One hundred patients were included. Frequencies of infarct-related artery thrombolysis in acute myocardial infarction (TIMI) flow rate classes 0, I and II in the IABP group (11.5, 1.9 and 7.7%, respectively) were significantly lower than in the control group (29.1, 14.6 and 22.9%, respectively) before PCI. After PCI, the frequency of TIMI class III flow rate in the IABP group (96.2%) was significantly higher than that in the control group (81.3%). Four weeks after PCI, the left ventricular ejection fraction (LVEF) was significantly higher, and the incidence of major cardiac events was significantly lower, in the IABP group compared with the control group.
  
  
  CONCLUSIONS
  Early use of IABP counterpulsation in STEMI patients scheduled for PCI was effective, with a favourable safety profile. IABP counterpulsation reduced the incidence of major adverse cardiac events and improved LVEF. However, IABP devices must be used at an early stage, to obtain optimal results.
authors.affiliation: Department of Cardiology, The First Affiliated Hospital of Henan Science and Technology University, Luoyang, China.
authors.forename: Zhijuan
authors.initials: Z
authors.lastname: Li
authors.forename: Pingshuan
authors.initials: P
authors.lastname: Dong
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Liu
authors.forename: Xuming
authors.initials: X
authors.lastname: Yang
authors.forename: Ke
authors.initials: K
authors.lastname: Wang
authors.forename: Zhiguo
authors.initials: Z
authors.lastname: Li
authors.forename: Yuwei
authors.initials: Y
authors.lastname: Zhao
authors.forename: Guoqing
authors.initials: G
authors.lastname: Jin
authors.forename: Zhuanzen
authors.initials: Z
authors.lastname: Li
authors.forename: Chunyan
authors.initials: C
authors.lastname: Li
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D017558:Elective Surgical Procedures; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006353:Heart-Assist Devices; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology / Q000601:surgery* / Q000628:therapy*; D013318:Stroke Volume / Q000502:physiology; D013997:Time Factors; D016896:Treatment Outcome
keywords: Intra-aortic balloon pump; myocardial infarction; percutaneous coronary intervention; transluminal angioplasty