title: Fatal disseminated Scedosporium prolificans infection initiated by ophthalmic involvement in a patient with acute myeloblastic leukemia.
abstract: Scedosporium prolificans is an opportunistic saprophytic fungus that rapidly disseminates and is intrinsically resistant to currently available antifungal drugs. We report a fatal case of disseminated S. prolificans infection that started with orbital and ocular involvement in a patient with secondary acute myeloblastic leukemia.
authors.affiliation: Institute for Applied Ophthalmobiology (IOBA), University of Valladolid, 47011 Valladolid, Spain. rreinosot@ioba.med.uva.es
authors.forename: Roberto
authors.initials: R
authors.lastname: Reinoso
authors.forename: Ester
authors.initials: E
authors.lastname: Carreño
authors.forename: Denise
authors.initials: D
authors.lastname: Hileeto
authors.forename: Alfredo
authors.initials: A
authors.lastname: Corell
authors.forename: J Carlos
authors.initials: JC
authors.lastname: Pastor
authors.forename: Mónica
authors.initials: M
authors.lastname: Cabrero
authors.forename: Lourdes
authors.initials: L
authors.lastname: Vázquez
authors.forename: Margarita
authors.initials: M
authors.lastname: Calonge
mesh_terms: D003881:Dermatomycoses / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D015821:Eye Infections, Fungal / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D016469:Fungemia / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000188:drug therapy; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D058889:Molecular Typing; D016533:Mycological Typing Techniques; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D021681:Scedosporium / Q000235:genetics / Q000302:isolation & purification*