title: Urological complications after 134 pediatric kidney transplants: a single-center study.
abstract: The incidence of surgical complications after kidney transplantation has been reported to range from 1% to 33%. The aim of this work was to report surgical urological complications among our cohort of 134 pediatric kidney transplantations. Epidemiological and clinical data of all patients younger than 18 years transplanted between January 1984 and May 2012 were collected from our prospective database. Urologic complications and management are reported herein. One hundred twenty-four patients, including 44% females underwent 134 renal transplants. Median age at the time of the surgery was 13 years. Mean time of end-stage renal disease was 25 months. We identified 10 subjects (7.5%) with urological complications: 5 ureterovesical stenoses, 2 lymphoceles, and 3 lower ureteral fistulas. All of the renal allografts were obtained from cadaveric donors. Mean age of these patients at the time of transplantation was 13 years. Mean cold ischemia time was 1613 minutes. All the patients required surgical management. All patients with ureterovesical stenoses underwent ureteral reimplantation using a Boari flap; those with lymphoceles underwent open marsupialization; 2 with ureteral fistulas underwent reimplantation of the ureter, and the other patient's case required placement of a nephrostomy tube and an antegrade ureteral catheter. All patients were treated successfully. Mean follow-up time of cases with urological complications was 9.5 years. Currently, 60% has nonfunctioning allografts; the mean current glomerular filtration rate of the functioning renal allografts is 55 mL/min. Despite requiring surgical management, all patients were treated successfully. Prompt identification and treatment of any complication are critical for graft and patient survival.
authors.affiliation: Department of Urology, Centro Hospitalar Porto, Porto, Portugal. fa1escorcio@gmail.com
authors.forename: F
authors.initials: F
authors.lastname: Almeida
authors.forename: F
authors.initials: F
authors.lastname: Branco
authors.forename: V
authors.initials: V
authors.lastname: Cavadas
authors.forename: S
authors.initials: S
authors.lastname: Ribeiro
authors.forename: L
authors.initials: L
authors.lastname: Osório
authors.forename: A
authors.initials: A
authors.lastname: Rocha
authors.forename: M
authors.initials: M
authors.lastname: Ramos
authors.forename: L
authors.initials: L
authors.lastname: Martins
authors.forename: A
authors.initials: A
authors.lastname: Castro-Henriques
authors.forename: C
authors.initials: C
authors.lastname: Mota
authors.forename: A
authors.initials: A
authors.lastname: Reis
authors.forename: A
authors.initials: A
authors.lastname: Fraga
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D008297:Male; D014570:Urologic Diseases / Q000209:etiology* / Q000473:pathology