title: Larvicidal activities of some Iranian native plants against the main malaria vector, Anopheles stephensi.
abstract: Malaria is considered a major health problem in Iran. There are different methods for vector control. In this study we tested the larvicidal effects of some Iranian plants. The methanolic extracts of 11 plants were prepared with percolation method. The larvicidal activities of them against malaria vector, Anopheles stephensi were studied using World Health Organization standard method. All LC50 values of methanolic extracts of plants that we screened were lower than 300 ppm. The methanolic extract of aerial parts of Lawsonia inermis and Stachys byzantina showed high larvicidal activity with LC50 values 69.40 ppm and 103.28 ppm respectively. The results obtained from this study suggest that the methanolic extracts of these plants have larvicidal effects against Anopheles stephensi larvae and could be useful in the search for new natural larvicidal compounds.
authors.affiliation: Department of Pharmacognosy and Traditional Iranian Medicine Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mahnaz
authors.initials: M
authors.lastname: Khanavi
authors.forename: Hassan
authors.initials: H
authors.lastname: Vatandoost
authors.forename: Nafiseh
authors.initials: N
authors.lastname: Khosravi Dehaghi
authors.forename: Alireza
authors.initials: A
authors.lastname: Sanei Dehkordi
authors.forename: Mohammad Mehdi
authors.initials: MM
authors.lastname: Sedaghat
authors.forename: Abbas
authors.initials: A
authors.lastname: Hadjiakhoondi
authors.forename: Farzaneh
authors.initials: F
authors.lastname: Hadjiakhoondi
mesh_terms: D000818:Animals; D000852:Anopheles / Q000187:drug effects*; D028203:Cedrus; D007303:Insect Vectors / Q000187:drug effects*; D007306:Insecticides / Q000494:pharmacology; D007492:Iran; D007814:Larva / Q000187:drug effects; D031564:Lawsonia Plant; D007928:Lethal Dose 50; D008288:Malaria / Q000517:prevention & control / Q000635:transmission; D010936:Plant Extracts / Q000494:pharmacology*; D018515:Plant Leaves; D031366:Stachys; D046930:Thymus Plant
chemical_list: D007306:Insecticides; D010936:Plant Extracts