title: Capable of identifying risk factors for placental abruption.
abstract: OBJECTIVE
  To clarify the capability of identifying risk factors for placental abruption (PA) during the antenatal and the peripartum period.
  
  
  METHODS
  Case-controlled study with matched pairs (1:5) was conducted. In total, 123 women with PA and 615 without PA who delivered singleton babies after 24 weeks of gestation were enrolled. The subjects were subdivided into three groups: women with PA during labor and delivery, PA during the antenatal period and clinically small PA. The clinical risk factors for PA in these groups were analyzed.
  
  
  RESULTS
  After performing multivariate logistic regression analyses, the risk factors for PA during labor and delivery were identified to be the presence of anemia before 20 weeks [adjusted odds ratio (aOR) 4.05] and small for gestational age (SGA) fetuses (aOR 5.20), while the risk factors for PA during the antenatal period were identified to be SGA fetuses (aOR 5.39), preterm uterine contractions (aOR 5.96) and preeclampsia (aOR 3.37). The risk factor associated with clinically small PA was the presence of anemia before 20 weeks (aOR 6.41).
  
  
  CONCLUSIONS
  It was likely that the etiologies differ between cases of PA that occur during the antenatal period and cases that occur after the onset of labor.
authors.affiliation: Department of Obstetrics and Gynecology, Showa University School of Medicine , Tokyo , Japan.
authors.forename: Junichi
authors.initials: J
authors.lastname: Hasegawa
authors.forename: Masamitsu
authors.initials: M
authors.lastname: Nakamura
authors.forename: Shoko
authors.initials: S
authors.lastname: Hamada
authors.forename: Kiyotake
authors.initials: K
authors.lastname: Ichizuka
authors.forename: Ryu
authors.initials: R
authors.lastname: Matsuoka
authors.forename: Akihiko
authors.initials: A
authors.lastname: Sekizawa
authors.forename: Takashi
authors.initials: T
authors.lastname: Okai
mesh_terms: D000037:Abruptio Placentae / Q000453:epidemiology / Q000209:etiology*; D000328:Adult; D000740:Anemia / Q000150:complications / Q000453:epidemiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D008297:Male; D016555:Matched-Pair Analysis; D015999:Multivariate Analysis; D007744:Obstetric Labor Complications / Q000453:epidemiology; D007752:Obstetric Labor, Premature / Q000453:epidemiology; D011225:Pre-Eclampsia / Q000453:epidemiology; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000453:epidemiology; D012307:Risk Factors; D014590:Uterine Contraction