title: Antisynthethase syndrome presenting as peripheral limb fasciitis.
abstract: Inflammatory myopathy is a major clinical manifestation of the antisynthetase syndrome. Patients with anti Jo-1 antibodies can also present with other clinical manifestations as arthritis, mechanic's hands and lung fibrosis. As in dermatomyositis, polymyositis and overlap myopathies proximal muscle of the limbs are preferentialy involved. Associated fascia edema on magnetic resonance imagery studies with histological proven fasciitis has been reported. However peripheral limb involvement, reported here in two patients, as the isolated initial manifestation is unusual.
authors.affiliation: Service de médecine interne, AP-HM, Aix-Marseille Université, 13385 Marseille cedex 5, France.
authors.forename: Mikael
authors.initials: M
authors.lastname: Ebbo
authors.forename: Christophe
authors.initials: C
authors.lastname: Chagnaud
authors.forename: Dominique
authors.initials: D
authors.lastname: Figarella-Branger
authors.forename: Stevan
authors.initials: S
authors.lastname: Legall
authors.forename: Jean-Robert
authors.initials: JR
authors.lastname: Harle
authors.forename: Nicolas
authors.initials: N
authors.lastname: Schleinitz
mesh_terms: D000328:Adult; D005121:Extremities; D005208:Fasciitis / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D009220:Myositis / Q000175:diagnosis*
keywords: Antisynthetase syndrome; Dermatomyositis; Fasciitis; Muscle MRI