title: [Diabetes in liver cirrhosis].
abstract: The prevalence of overt diabetes mellitus (DM) in liver cirrhosis is about 30%. However, DM or impaired glucose tolerance can be observed in 90% after an oral glucose tolerance test in patients with normal fasting plasma glucose. Type 2 DM may produce cirrhosis, whereas DM may be a complication of cirrhosis. The latter is known as «hepatogenous diabetes». Overt and subclinical DM is associated with liver complications and death in cirrhotic patients. Treating diabetes is difficult in cirrhotic patients because of the metabolic impairments due to liver disease and because the most appropriate pharmacologic treatment has not been defined. It is also unknown if glycemic control with hypoglycemic agents has any impact on the course of the liver disease.
authors.affiliation: Servicio de Gastroenterología y Departamento de Medicina Interna, Hospital Universitario Dr. José E. González, Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, México. digarciacompean@prodigy.net.mx
authors.forename: Diego
authors.initials: D
authors.lastname: García-Compeán
authors.forename: Joel O
authors.initials: JO
authors.lastname: Jáquez-Quintana
authors.forename: José A
authors.initials: JA
authors.lastname: González-González
authors.forename: Fernando J
authors.initials: FJ
authors.lastname: Lavalle-González
authors.forename: Jesús Z
authors.initials: JZ
authors.lastname: Villarreal-Pérez
authors.forename: Hector J
authors.initials: HJ
authors.lastname: Maldonado-Garza
mesh_terms: D048909:Diabetes Complications / Q000150:complications* / Q000628:therapy; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications*
keywords: Cirrosis hepática; Curva de tolerancia oral a la glucosa; Diabetes mellitus; Liver cirrhosis; Mortalidad ;; Mortality; Oral glucose tolerance test