title: No influence of simultaneous bone-substitute application on the success of immediately loaded dental implants: a retrospective cohort study.
abstract: OBJECTIVE
  To examine the influence of bone-substitute application during implantation on the success of immediately placed and loaded dental implants.
  
  
  METHODS
  A total of 147 consecutive patients (age, 16.5-80.4 years) were provided with 696 immediately loaded implants. The mean follow-up time was 34.1 months. Of these implants, 50.4% (n=351) were immediately placed into extraction sockets. A total of 119 implants were added by simultaneous bone-substitute application (NanoBone, Artoss GmbH, Rostock Germany), whereas the other implants were placed in healed bone. Univariate and multivariate analysis was performed using IBM SPSS V.20.
  
  
  RESULTS
  The overall implant success rate was 96.1%. Implants with simultaneous bone replacement had a hazard ratio of 0.877 (p=0.837); 95% CI, 0.253-3.04). Factors found to be statistically significant modifiers of success on multivariate analysis (p<0.05) included type of superstructure (p<0.001), implant-abutment connection (p<0.001), membrane use (p=0.010), and jaw (p=0.026). None of the other factors investigated were significant modifiers.
  
  
  CONCLUSIONS
  The present study demonstrates high success rates for immediately loaded implants and their superstructures independent of the simultaneous application of bone substitute. The declared aim of socket preservation, the prevention avoiding bone loss, is achieved in the immediate implant placement scenario under immediate-loading conditions.
authors.affiliation: dres.kopp@t-online.de
authors.forename: Sigmar
authors.initials: S
authors.lastname: Kopp
authors.forename: Detlef
authors.initials: D
authors.lastname: Behrend
authors.forename: Günther
authors.initials: G
authors.lastname: Kundt
authors.forename: Peter
authors.initials: P
authors.lastname: Ottl
authors.forename: Bernhard
authors.initials: B
authors.lastname: Frerich
authors.forename: Mareike
authors.initials: M
authors.lastname: Warkentin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018786:Bone Substitutes / Q000008:administration & dosage*; D015331:Cohort Studies; D003131:Combined Modality Therapy / Q000706:statistics & numerical data; D015921:Dental Implants; D019094:Dental Prosthesis, Implant-Supported / Q000706:statistics & numerical data*; D019232:Dental Restoration Failure / Q000706:statistics & numerical data*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D057893:Immediate Dental Implant Loading / Q000379:methods* / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012189:Retrospective Studies; D020390:Tooth Socket / Q000000981:diagnostic imaging / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D018786:Bone Substitutes; D015921:Dental Implants