title: [Diabetes and kidneys].
abstract: Diabetic nephropathy is the leading cause of end-stage renal disease all over the world. Diagnosis is confirmed by measuring urin albumin excretion and calculated renal function (eGFR). Once the diagnosis is confirmed there should be a search for confounding cardiovascular risk factors and even established cardiovascular disease because of the associated high cardiovascular risk. In type 1 diabetes metabolic control is the main issue. In case of renal impairment and in patients with type 2 diabetes a multifactorial approach is necessary, which consists of dietary advise, metabolic control, lowering elevated blood-pressure, cessation of smoking, ASS and lipid-lowering drug-therapy. Special drugs for the treatment of diabetes-induced renal disease are not available.
authors.affiliation: Praxis für Nierenerkrankungen und Diabetes Bochum. dirk.gaeckler@dialyse-bochum.de
authors.forename: D
authors.initials: D
authors.lastname: Gäckler
authors.forename: S
authors.initials: S
authors.lastname: Jäkel
authors.forename: L
authors.initials: L
authors.lastname: Fricke
authors.forename: B
authors.initials: B
authors.lastname: Reinsch
authors.forename: F
authors.initials: F
authors.lastname: Fischer
mesh_terms: D000328:Adult; D000419:Albuminuria / Q000175:diagnosis / Q000628:therapy; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000628:therapy; D002648:Child; D003131:Combined Modality Therapy; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D003928:Diabetic Nephropathies / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy; D005060:Europe; D006801:Humans; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D007677:Kidney Function Tests