title: 18F-fluoride PET/CT aspect of an unusual case of Erdheim-Chester disease with histologic features of Langerhans cell histiocytosis.
abstract: We report the case of a 63-year-old woman with Erdheim-Chester disease (ECD) and histologic features of Langerhans cell histiocytosis, both extremely rare histiocytic proliferations responsible of skeletal and extraskeletal involvement. 18F-Fluoride PET/CT revealed multiple intense focal uptake scattered throughout the skeleton. We also performed an 18F-FDG PET/CT which point out visceral and vascular involvement. This case illustrates the interest of PET/CT in ECD, a rare polymorphus and systemic disease, and in our knowledge, this is the first reported illustration of 18F-fluoride PET/CT findings in this pathology.
authors.affiliation: Universite de Franche-Comte, Besançon, France. caocilou@yahoo.fr
authors.forename: Cécile
authors.initials: C
authors.lastname: Caoduro
authors.forename: Constantin Marius
authors.initials: CM
authors.lastname: Ungureanu
authors.forename: Boris
authors.initials: B
authors.lastname: Rudenko
authors.forename: Orland
authors.initials: O
authors.lastname: Angoue
authors.forename: Oleg
authors.initials: O
authors.lastname: Blagosklonov
authors.forename: Frédéric
authors.initials: F
authors.lastname: Paycha
authors.forename: Hatem
authors.initials: H
authors.lastname: Boulahdour
mesh_terms: D031249:Erdheim-Chester Disease / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D005459:Fluorides; D005462:Fluorine Radioisotopes; D006646:Histiocytosis, Langerhans-Cell / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D051598:Whole Body Imaging
chemical_list: D005462:Fluorine Radioisotopes; D005459:Fluorides