title: Multiparametric MRI of prostate cancer: an update on state-of-the-art techniques and their performance in detecting and localizing prostate cancer.
abstract: Magnetic resonance (MR) examinations of men with prostate cancer are most commonly performed for detecting, characterizing, and staging the extent of disease to best determine diagnostic or treatment strategies, which range from biopsy guidance to active surveillance to radical prostatectomy. Given both the exam's importance to individual treatment plans and the time constraints present for its operation at most institutions, it is essential to perform the study effectively and efficiently. This article reviews the most commonly employed modern techniques for prostate cancer MR examinations, exploring the relevant signal characteristics from the different methods discussed and relating them to intrinsic prostate tissue properties. Also, a review of recent articles using these methods to enhance clinical interpretation and assess clinical performance is provided. J. Magn. Reson. Imaging 2013;37:1035-1054. © 2013 Wiley Periodicals, Inc.
authors.affiliation: Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: John V
authors.initials: JV
authors.lastname: Hegde
authors.forename: Robert V
authors.initials: RV
authors.lastname: Mulkern
authors.forename: Lawrence P
authors.initials: LP
authors.lastname: Panych
authors.forename: Fiona M
authors.initials: FM
authors.lastname: Fennessy
authors.forename: Andriy
authors.initials: A
authors.lastname: Fedorov
authors.forename: Stephan E
authors.initials: SE
authors.lastname: Maier
authors.forename: Clare M C
authors.initials: CM
authors.lastname: Tempany
mesh_terms: D005544:Forecasting; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation* / Q000379:methods*; D008297:Male; D011467:Prostate / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*