title: [Not Available].
abstract: The effect of ochratoxin A (OTA) and C (OTC) on the cytolytic activity of natural killer cells (NK cells) was studied using a fluorescence based bioassay with the cell line NK-92 as effector cell line and K-562 as target cell line. Different OTA and OTC preparations were included in the study. After exposure to very low toxin concentrations (1-10 ng/ml) a slight stimulation of NK cell activity was noted, whereas after addition of higher toxin concentrations (100-1000 ng/ml) NK cell function was suppressed. Preparations containing OTC showed a stronger effect than those containing OTA.
authors.affiliation: Bundesinstitut für gesundheitlichen Verbraucherschutz und Veterinärmedizin Fachbereich 4, Naumburger Str. 96a, D-07743, Jena.
authors.forename: M
authors.initials: M
authors.lastname: Heller
authors.forename: H
authors.initials: H
authors.lastname: Köhler
authors.forename: B
authors.initials: B
authors.lastname: Burkert
authors.forename: B
authors.initials: B
authors.lastname: Rohrmann
authors.forename: S
authors.initials: S
authors.lastname: Thierbach
authors.forename: G
authors.initials: G
authors.lastname: Müller