title: Redefining KSHV latency.
abstract: In this issue of Cell Host & Microbe, Chang and Ganem (2013) report that Kaposi's sarcoma-associated herpesvirus infection of lymphatic endothelial cells (LECs), but not blood endothelial cells (BECs), activates mTORC1 signaling and sensitizes LECs to rapamycin-induced killing. The differential rapamycin sensitivity is explained by a unique LEC-specific virus latency program.
authors.affiliation: Cancer Research UK Viral Oncology Group, UCL Cancer Institute, Huntley Street, University College London, London WC1E 6BT, UK.
authors.forename: Ohad
authors.initials: O
authors.lastname: Yogev
authors.forename: Chris
authors.initials: C
authors.lastname: Boshoff