title: Roquin paralogs add a new dimension to ICOS regulation.
abstract: Two studies in the current issue of Immunity (Pratama et al., 2013; Vogel et al., 2013) demonstrate that the RNA-binding proteins Roquin-1 and Roquin-2 have redundant function in the posttranscriptional repression of Icos messenger RNA by CD4(+) T cells.
authors.affiliation: Department of Immunobiology, Yale School of Medicine, New Haven, CT 06510, USA.
authors.forename: Sarah A
authors.initials: SA
authors.lastname: Bertino
authors.forename: Joe
authors.initials: J
authors.lastname: Craft