title: Two-photon probes for biomedical applications.
abstract: Two-photon microscopy (TPM), which uses two photons of lower energy as the excitation source, is a vital tool in biology and clinical science, due to its capacity to image deep inside intact tissues for a long period of time. To make TPM a more versatile tool in biomedical research, we have developed a variety of two-photon probes for specific applications. In this mini review, we will briefly discuss two-photon probes for lipid rafts, lysosomes, mitochondria, and pH, and their biomedical applications.
authors.affiliation: Department of Chemistry, Korea University, Seoul 136-701, Korea.
authors.forename: Chang Su
authors.initials: CS
authors.lastname: Lim
authors.forename: Bong Rae
authors.initials: BR
authors.lastname: Cho
mesh_terms: D001343:Autophagy; D004941:Esophagitis / Q000503:physiopathology; D005456:Fluorescent Dyes / Q000737:chemistry; D006801:Humans; D008051:Lipid Bilayers / Q000737:chemistry / Q000378:metabolism; D008247:Lysosomes / Q000473:pathology; D018613:Microscopy, Confocal; D008928:Mitochondria / Q000473:pathology; D015335:Molecular Probes / Q000737:chemistry* / Q000378:metabolism; D017785:Photons
chemical_list: D005456:Fluorescent Dyes; D008051:Lipid Bilayers; D015335:Molecular Probes