title: Anticancer activities of PPARγ in breast cancer are context-dependent.
abstract: This Commentary highlights the article by Nakles et al, who described that PPARγ activation suppresses non-invasive tumor development and induces ER-positivity without affecting invasive tumor development.
authors.affiliation: Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA.
authors.forename: Jin-Tang
authors.initials: JT
authors.lastname: Dong
mesh_terms: D000818:Animals; D016588:Anticarcinogenic Agents / Q000627:therapeutic use*; D005260:Female; D019398:Genes, BRCA1; D008325:Mammary Neoplasms, Experimental / Q000517:prevention & control*; D009154:Mutation; D047495:PPAR gamma / Q000819:agonists*; D045162:Thiazolidinediones / Q000627:therapeutic use*
chemical_list: D016588:Anticarcinogenic Agents; D047495:PPAR gamma; D045162:Thiazolidinediones; C510342:efatutazone