title: [Heparins and skin reactions: from diagnostic to management].
abstract: The use of heparins in the prophylaxis and treatment of thromboembolic diseases shows non-negligible risks of cutaneous lesions, which are very frequently underestimated by physicians. As this risk often originates from either delayed-type hypersensitivity reactions or life-threatening heparin-induced thrombocytopenia, a quick diagnosis and an adapted management are thus crucial. Furthermore, as most cases are emergencies, allergologic testing cannot be considered in the first place. In this context, an overview of the therapeutic as well as management recommendations is presented, taking into account the most recent treatments.
authors.affiliation: Service de dermatologie et vénéréologie, Département des spécialités de médecine, HUG, 1211 Genève 14 neda.barouti@hcuge.ch
authors.forename: Neda
authors.initials: N
authors.lastname: Barouti
authors.forename: Isabelle
authors.initials: I
authors.lastname: Masouyé
authors.forename: Wolf-Henning
authors.initials: WH
authors.lastname: Boehncke
authors.forename: Christa
authors.initials: C
authors.lastname: Prins
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D003875:Drug Eruptions / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D006493:Heparin / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced; D013921:Thrombocytopenia / Q000139:chemically induced; D013923:Thromboembolism / Q000188:drug therapy
chemical_list: D000925:Anticoagulants; D006493:Heparin