title: A case series of de novo inflammatory bowel disease after kidney transplantation.
abstract: Diarrhea, which is common after transplantation, may be due to infections and immunosuppressive therapy. Inflammatory bowel disease (IBD) de novo or as an exacerbation of pre-existent disease is a rare complication after kidney transplantation with pre-existing disease having a less aggressive clinical course than the de novo disease. Cytomegalovirus mismatch, prescription of tacrolimus instead of cyclosporine or mycophenolate mofetil rather than azathioprine as well as low-dose corticosteroid treatments have been linked to an increased incidence of IBD. This series of renal transplant recipients with de novo IBD showed a higher incidence and more aggressive course than that previously described, possibly related to increased use of tacrolimus with minimization of steroids.
authors.affiliation: Department of Nephrology, Centro Hospitalar do Porto, Santo António Hospital, Porto, Portugal. pedronunesazevedo@gmail.com
authors.forename: P
authors.initials: P
authors.lastname: Azevedo
authors.forename: C
authors.initials: C
authors.lastname: Freitas
authors.forename: P
authors.initials: P
authors.lastname: Aguiar
authors.forename: H
authors.initials: H
authors.lastname: Silva
authors.forename: T
authors.initials: T
authors.lastname: Santos
authors.forename: P
authors.initials: P
authors.lastname: Farrajota
authors.forename: M
authors.initials: M
authors.lastname: Almeida
authors.forename: S
authors.initials: S
authors.lastname: Pedroso
authors.forename: L S
authors.initials: LS
authors.lastname: Martins
authors.forename: L
authors.initials: L
authors.lastname: Dias
authors.forename: R
authors.initials: R
authors.lastname: Vizcaíno
authors.forename: A Castro
authors.initials: AC
authors.lastname: Henriques
authors.forename: A
authors.initials: A
authors.lastname: Cabrita
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D015212:Inflammatory Bowel Diseases / Q000139:chemically induced*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged
chemical_list: D007166:Immunosuppressive Agents