title: Synthesis of fluorine-containing multisubstituted phenanthridines by rhodium-catalyzed alkyne [2+2+2] cycloaddition and tandem sp² C-H difluoromethylenation.
abstract: A highly efficient method for the synthesis of fluorine-containing multisubstituted phenanthridines through Rh-catalyzed alkyne [2+2+2] cycloaddition reactions has been developed. This method exhibits excellent functional-group compatibility. When a bromodifluoromethyl group, rather than a trifluoromethyl group, was employed in the cycloaddition reaction, more-complicated polycyclic compounds were obtained through tandem Rh-catalyzed cycloaddition/C-H difluoromethylenation. This route provides convenient access to fluorine-containing polycyclic compounds.
authors.affiliation: School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan, Hubei 430074, PR China.
authors.forename: Yajun
authors.initials: Y
authors.lastname: Li
authors.forename: Jiangtao
authors.initials: J
authors.lastname: Zhu
authors.forename: Lisi
authors.initials: L
authors.lastname: Zhang
authors.forename: Yongming
authors.initials: Y
authors.lastname: Wu
authors.forename: Yuefa
authors.initials: Y
authors.lastname: Gong