title: Regioselective di- and tetra-functionalisation of γ-cyclodextrin using capping methodology.
abstract: Alkylation of γ-cyclodextrin with 3 equiv. of 1,3-bis[bis(4-tert-butylphenyl)chloromethyl]benzene, followed by permethylation afforded selectively a singly capped (A,B), as well as two doubly capped (A,B:D,E and A,B:E,F) methylated γ-CDs. Deprotection with HBF4 gave quantitatively the corresponding diols and tetrols, which constitute valuable starting compounds for further functionalisation.
authors.affiliation: Laboratoire de Chimie Inorganique Moléculaire et Catalyse, Institut de Chimie UMR 7177 CNRS, Université de Strasbourg, 1, rue Blaise Pascal, 67008 Strasbourg cedex, France.
authors.forename: Matthieu
authors.initials: M
authors.lastname: Jouffroy
authors.forename: Dominique
authors.initials: D
authors.lastname: Armspach
authors.forename: Dominique
authors.initials: D
authors.lastname: Matt
authors.forename: Loïc
authors.initials: L
authors.lastname: Toupet