title: Cost-effectiveness of novel system of mosquito surveillance and control, Brazil.
abstract: Of all countries in the Western Hemisphere, Brazil has the highest economic losses caused by dengue fever. We evaluated the cost-effectiveness of a novel system of vector surveillance and control, Monitoramento Inteligente da Dengue (Intelligent Dengue Monitoring System [MID]), which was implemented in 21 cities in Minas Gerais, Brazil. Traps for adult female mosquitoes were spaced at 300-m intervals throughout each city. In cities that used MID, vector control was conducted specifically at high-risk sites (indicated through daily updates by MID). In control cities, vector control proceeded according to guidelines of the Brazilian government. We estimated that MID prevented 27,191 cases of dengue fever and saved an average of $227 (median $58) per case prevented, which saved approximately $364,517 in direct costs (health care and vector control) and $7,138,940 in lost wages (societal effect) annually. MID was more effective in cities with stronger economies and more cost-effective in cities with higher levels of mosquito infestation.
authors.affiliation: National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Kim M
authors.initials: KM
authors.lastname: Pepin
authors.forename: Cecilia
authors.initials: C
authors.lastname: Marques-Toledo
authors.forename: Luciano
authors.initials: L
authors.lastname: Scherer
authors.forename: Maira M
authors.initials: MM
authors.lastname: Morais
authors.forename: Brett
authors.initials: B
authors.lastname: Ellis
authors.forename: Alvaro E
authors.initials: AE
authors.lastname: Eiras
mesh_terms: D000330:Aedes / Q000821:virology*; D000818:Animals; D001938:Brazil / Q000453:epidemiology; D002947:Cities / Q000191:economics / Q000453:epidemiology; D003362:Cost-Benefit Analysis; D003715:Dengue / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission / Q000821:virology; D003716:Dengue Virus / Q000302:isolation & purification; D004196:Disease Outbreaks / Q000191:economics* / Q000517:prevention & control; D005260:Female; D006801:Humans; D015994:Incidence; D007303:Insect Vectors / Q000821:virology*; D009032:Mosquito Control / Q000191:economics* / Q000379:methods
keywords: Aedes aegypti; Brazil; cost-effectiveness; dengue; dengue virus; mosquito control; mosquito surveillance; viruses