title: Bioprosthetic mitral valve endocarditis after percutaneous device closure of severe paravalvular leak.
abstract: A large mitral paravalvular leak in a 63-year-old patient was closed by percutaneous placement of 2 Amplatzer Septal Occluder (AGA Medical Corporation, Plymouth, MN) devices. The patient had a residual paravalvular leak and subsequently developed infective endocarditis that was successfully treated by removal of all hardware and implantation of a new valve. Transcatheter treatment of paravalvular leaks may be useful in select patients who are poor candidates for open surgery; however, one must be aware of the potential complications. This report underscores the risk of device infection that may be increased if there is turbulence related to residual paravalvular leaks.
authors.affiliation: Division of Cardiothoracic Surgery, the Michael E. DeBakey Department of Surgery, Houston, TX 77030, USA.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Tuluca
authors.forename: Raed
authors.initials: R
authors.lastname: Al-Najjar
authors.forename: Lorraine D
authors.initials: LD
authors.lastname: Cornwell
authors.forename: Alvin
authors.initials: A
authors.lastname: Blaustein
authors.forename: Richard
authors.initials: R
authors.lastname: Hamill
authors.forename: Rabih O
authors.initials: RO
authors.lastname: Darouiche
authors.forename: Faisal G
authors.initials: FG
authors.lastname: Bakaeen
mesh_terms: D001705:Bioprosthesis / Q000009:adverse effects*; D004696:Endocarditis / Q000209:etiology*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D055989:Septal Occluder Device / Q000009:adverse effects*