title: The expression of leptin receptor in the ovary of the queen: leptin receptor expression in queen ovary.
abstract: Leptin is a Ob gene product secreted mainly by adipose tissue. Several reports showed leptin production by other tissue including the ovary. The action of leptin is mediated upon binding to its receptor widely expressed in reproductive tissues in different species. In fact, there are growing evidences that leptin plays an important role in the modulation of reproductive functions. Therefore, the aim of this study was to evaluate in the queen, the expression of leptin receptor during the functional ovarian cycle and pregnancy. We found that the ovaries of the queen express leptin receptor in all the examined phases. The highest leptin receptor expression was found in the luteal phase (pseudopregnancy, pregnancy) compared to other phases of the cycle (anestrus, proestrus, estrus). The variations in the expression of leptin receptor suggest a likely implication of leptin in the modulation of ovarian activity, in the examined species.
authors.affiliation: Department of Emergency and Organs Transplantation (DETO)-Unit of Veterinary Clinics and Animal Productions, University of Bari Aldo Moro, Strada Prov.Le Per Casamassima Km 3, 70010 Valenzano, Bari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Albrizio
authors.forename: M T
authors.initials: MT
authors.lastname: Roscino
authors.forename: C
authors.initials: C
authors.lastname: Trisolini
authors.forename: F
authors.initials: F
authors.lastname: Binetti
authors.forename: A
authors.initials: A
authors.lastname: Rizzo
authors.forename: R L
authors.initials: RL
authors.lastname: Sciorsci
mesh_terms: D000818:Animals; D002415:Cats / Q000502:physiology*; D030762:Estrous Cycle / Q000502:physiology*; D005260:Female; D005786:Gene Expression Regulation / Q000502:physiology*; D010053:Ovary / Q000378:metabolism*; D011247:Pregnancy; D011555:Pseudopregnancy / Q000378:metabolism; D054411:Receptors, Leptin / Q000235:genetics / Q000378:metabolism*
chemical_list: D054411:Receptors, Leptin
keywords: Estrus cycle; Leptin receptor; Luteal phase; Queen