title: Hypoiodite mediated synthesis of isoxazolines from aldoximes and alkenes using catalytic KI and Oxone as the terminal oxidant.
abstract: Isoxazolines can be efficiently synthesized in good yields via a hypoiodite mediated catalytic oxidative cyclization of aldoximes and alkenes. This reaction involves active iodine species generated in situ from catalytic amounts of KI and Oxone.
authors.affiliation: Department of Chemistry and Biochemistry, University of Minnesota Duluth, Duluth, USA. ayoshimu@d.umn.edu
authors.forename: Akira
authors.initials: A
authors.lastname: Yoshimura
authors.forename: Chenjie
authors.initials: C
authors.lastname: Zhu
authors.forename: Kyle R
authors.initials: KR
authors.lastname: Middleton
authors.forename: Anthony D
authors.initials: AD
authors.lastname: Todora
authors.forename: Brent J
authors.initials: BJ
authors.lastname: Kastern
authors.forename: Andrey V
authors.initials: AV
authors.lastname: Maskaev
authors.forename: Viktor V
authors.initials: VV
authors.lastname: Zhdankin
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D017613:Iodine Compounds / Q000737:chemistry*; D007555:Isoxazoles / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry; D010091:Oximes / Q000737:chemistry*; D011193:Potassium Iodide / Q000737:chemistry*; D013464:Sulfuric Acids / Q000737:chemistry*
chemical_list: D000475:Alkenes; D017613:Iodine Compounds; D007555:Isoxazoles; D016877:Oxidants; D010091:Oximes; D013464:Sulfuric Acids; D011193:Potassium Iodide; C081961:hypoiodous acid; C048813:potassium peroxymonosulfuric acid