title: Localization of aquaporins in the mouse vestibular end organs.
abstract: CONCLUSIONS
  We found that aquaporins (AQPs) in the fluid transporting cells, such as vestibular dark cells and endolymphatic sac epithelial cells, seem to be of importance in fluid transport in the inner ear, while those in the sensory and ganglion cells may play a functional role in sensory cell transduction.
  
  
  OBJECTIVE
  Expression of AQPs (0-12) was analyzed in normal mouse vestibular end organs.
  
  
  METHODS
  CBA/J mice were used in this study. Localization of AQPs 0-12 in the vestibular end organs and endolymphatic sac was investigated by immunohistochemistry.
  
  
  RESULTS
  The AQPs were found abundantly distributed in many structures in the vestibular end organs, i.e. vestibular sensory and supporting cells, vestibular dark cells, vestibular ganglion cells, and the endolymphatic sac.
authors.affiliation: Department of Otolaryngology, Hiroshima University Hospital, Hiroshima, Japan. masati@hiroshima-u.ac.jp
authors.forename: Masaya
authors.initials: M
authors.lastname: Takumida
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Takumida
authors.forename: Akinobu
authors.initials: A
authors.lastname: Kakigi
authors.forename: Naoya
authors.initials: N
authors.lastname: Egami
authors.forename: Rie
authors.initials: R
authors.lastname: Nishioka
authors.forename: Matti
authors.initials: M
authors.lastname: Anniko
mesh_terms: D000818:Animals; D020346:Aquaporins / Q000378:metabolism*; D004712:Endolymphatic Sac / Q000378:metabolism*; D004847:Epithelial Cells / Q000378:metabolism; D017950:Ganglia, Sensory / Q000378:metabolism; D007150:Immunohistochemistry; D051379:Mice; D008808:Mice, Inbred CBA; D011984:Sensory Receptor Cells / Q000378:metabolism
chemical_list: D020346:Aquaporins