title: Imaging and treatment of patients with acute stroke: an evidence-based review.
abstract: Evidence-based medicine has emerged as a valuable tool to guide clinical decision-making, by summarizing the best possible evidence for both diagnostic and treatment strategies. Imaging plays a critical role in the evaluation and treatment of patients with acute ischemic stroke, especially those who are being considered for thrombolytic or endovascular therapy. Time from stroke-symptom onset to treatment is a strong predictor of long-term functional outcome after stroke. Therefore, imaging and treatment decisions must occur rapidly in this setting, while minimizing unnecessary delays in treatment. The aim of this review was to summarize the best available evidence for the diagnostic and therapeutic management of patients with acute ischemic stroke.
authors.affiliation: From the Departments of Radiology (P.C.S., J.B.S.)Public Health (P.C.S.), Weill Cornell Medical Center/NewYork-Presbyterian Hospital, New York, New York pcs9001@med.cornell.edu.
authors.forename: P C
authors.initials: PC
authors.lastname: Sanelli
authors.affiliation: From the Departments of Radiology (P.C.S., J.B.S.).
authors.forename: J B
authors.initials: JB
authors.lastname: Sykes
authors.affiliation: Departments of Neurology (A.L.F., J.-M.L.).
authors.forename: A L
authors.initials: AL
authors.lastname: Ford
authors.affiliation: Departments of Neurology (A.L.F., J.-M.L.)Radiology (J.-M.L., K.D.V.), Washington University, School of Medicine, St. Louis, Missouri.
authors.forename: J-M
authors.initials: JM
authors.lastname: Lee
authors.affiliation: Radiology (J.-M.L., K.D.V.), Washington University, School of Medicine, St. Louis, Missouri.
authors.forename: K D
authors.initials: KD
authors.lastname: Vo
authors.affiliation: Department of Radiology (D.K.H.), University of Washington Medical Center, Seattle, Washington.
authors.forename: D K
authors.initials: DK
authors.lastname: Hallam
mesh_terms: D002986:Clinical Trials as Topic; D019317:Evidence-Based Medicine; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015995:Prevalence; D011379:Prognosis; D020521:Stroke / Q000175:diagnosis* / Q000628:therapy*; D015912:Thrombolytic Therapy / Q000706:statistics & numerical data*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome