title: A motion direction preference map in monkey V4.
abstract: In the primate visual system, area V4 is located in the ventral pathway and is traditionally thought to be involved in processing color and form information. However, little is known about its functional role in processing motion information. Using intrinsic signal optical imaging over large fields of view in V1, V2, and V4, we mapped the direction of motion responses in anesthetized macaques. We found that V4 contains direction-preferring domains that are preferentially activated by stimuli moving in one direction. These direction-preferring domains normally occupy several restricted regions of V4 and tend to overlap with orientation- and color-preferring domains. Single-cell recordings targeting these direction-preferring domains also showed a clustering, as well as a columnar organization of V4 direction-selective neurons. These data suggest that, in contrast to the classical view, motion information is also processed in ventral pathway regions such as area V4.
authors.affiliation: Institute of Neuroscience and State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
authors.forename: Peichao
authors.initials: P
authors.lastname: Li
authors.forename: Shude
authors.initials: S
authors.lastname: Zhu
authors.forename: Ming
authors.initials: M
authors.lastname: Chen
authors.forename: Chao
authors.initials: C
authors.lastname: Han
authors.forename: Haoran
authors.initials: H
authors.lastname: Xu
authors.forename: Jiaming
authors.initials: J
authors.lastname: Hu
authors.forename: Yang
authors.initials: Y
authors.lastname: Fang
authors.forename: Haidong D
authors.initials: HD
authors.lastname: Lu
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001808:Blood Vessels / Q000033:anatomy & histology; D001931:Brain Mapping; D003118:Color Perception / Q000502:physiology; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D007091:Image Processing, Computer-Assisted; D008252:Macaca fascicularis; D008253:Macaca mulatta; D008297:Male; D009039:Motion Perception / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D061848:Optical Imaging; D009949:Orientation / Q000502:physiology*; D010775:Photic Stimulation; D017603:Signal Detection, Psychological / Q000502:physiology*; D014793:Visual Cortex / Q000166:cytology / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology