title: ATRP synthesis of poly(2-(methacryloyloxy)ethyl choline phosphate): a multivalent universal biomembrane adhesive.
abstract: A new monomer, 2-(methacryloyloxy)ethyl choline phosphate, and its direct polymerization into a polyvalent choline phosphate are described, providing a universal biomembrane adhesive exhibiting rapid, strong attachment to any mammalian cell membrane and fast internalization, properties of great value in applications such as tissue engineering and drug delivery.
authors.affiliation: Centre for Blood Research, University of British Columbia (UBC), 2350 Health Sciences Mall, Vancouver, V6T 1Z3, Canada.
authors.forename: Xifei
authors.initials: X
authors.lastname: Yu
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Yang
authors.forename: Sonja
authors.initials: S
authors.lastname: Horte
authors.forename: Jayachandran N
authors.initials: JN
authors.lastname: Kizhakkedathu
authors.forename: Donald E
authors.initials: DE
authors.lastname: Brooks
mesh_terms: D000269:Adhesives / Q000737:chemistry*; D000818:Animals; D016466:CHO Cells; D002462:Cell Membrane / Q000737:chemistry*; D003412:Cricetulus; D004903:Erythrocyte Aggregation; D004912:Erythrocytes / Q000737:chemistry*; D006801:Humans; D015394:Molecular Structure; D010767:Phosphorylcholine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*; D058105:Polymerization; D011109:Polymethacrylic Acids / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000269:Adhesives; D011109:Polymethacrylic Acids; C115766:poly(2-methacryloyloxyethyl-phosphorylcholine); D010767:Phosphorylcholine