title: Palladium-catalyzed decarboxylative arylation of benzoylacrylic acids toward the synthesis of chalcones.
abstract: It has been found that readily available 3-benzoylacrylic acids undergo palladium-catalyzed decarboxylative arylation with arylboronic acids in the presence of a copper salt oxidant to produce chalcone derivatives. The decarboxylative arylation could also be achieved using aryl halides as the alternative aryl source to expand the applicable scope.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Osaka University, Suita, Osaka 565-0871, Japan.
authors.forename: Yuto
authors.initials: Y
authors.lastname: Unoh
authors.forename: Koji
authors.initials: K
authors.lastname: Hirano
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Satoh
authors.forename: Masahiro
authors.initials: M
authors.lastname: Miura
mesh_terms: D000179:Acrylates / Q000737:chemistry*; D001565:Benzoates / Q000737:chemistry*; D002384:Catalysis; D047188:Chalcones / Q000138:chemical synthesis* / Q000737:chemistry; D003653:Decarboxylation; D015394:Molecular Structure; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D000179:Acrylates; D001565:Benzoates; D047188:Chalcones; D009942:Organometallic Compounds; C400967:benzoylacrylic acid; D010165:Palladium