title: Synchronous sporadic gastrointestinal stromal tumors in the stomach and jejunum: report of a case.
abstract: This report describes a patient with synchronous sporadic gastrointestinal stromal tumors (GISTs) in the stomach and jejunum. A 71-year-old Japanese male presented with a 2-year history of occasional melena and general fatigue. Computed tomography of the abdomen demonstrated an enhanced extramural gastric tumor, 4 cm in diameter. Endoscopic examination revealed a jejunal submucosal tumor. He was referred to the surgical outpatient clinic for surgical treatment of an extramural gastric tumor and a jejunal submucosal tumor. Laparotomy allowed the identification of a nut-sized extramural tumor at the stomach and a thumb's head-sized tumor on the jejunum. Partial resections of the stomach and jejunum were performed. Histopathological and immunohistochemical examination revealed that these tumors were GISTs. Although no molecular analysis was performed, the immunohistochemical staining patterns of these two tumors were different from each other. Therefore, the final diagnosis was synchronous sporadic GISTs in the stomach and jejunum. This patient has survived without recurrence for approximately 12 years since complete resection.
authors.affiliation: Department of Surgery 1, University of Occupational and Environmental Health, Kitakyushu, Japan ; Department of Gastroenterological and General Surgery, Wakamatsu Hospital of University of Occupational and Environmental Health, Kitakyushu, Japan.
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Nakayama
authors.forename: Kouji
authors.initials: K
authors.lastname: Kadowaki
authors.forename: Aiichirou
authors.initials: A
authors.lastname: Higure
authors.forename: Masanori
authors.initials: M
authors.lastname: Hisaoka
authors.forename: Koji
authors.initials: K
authors.lastname: Yamaguchi
keywords: Gastrointestinal stromal tumor; Jejunum; Sporadic; Stomach; Synchronous