title: Tea and human health: the dark shadows.
abstract: Tea is one of the most popularly consumed beverage. Depending on the manufacturing process, different varieties of tea can be produced. The antioxidative and antimutagenic potential of tea in cardiovascular diseases, cancer and obesity have long been studied. These therapeutic and nutritional benefits of tea can be attributed to the presence of flavanoids. However, these flavanoids also have certain detrimental effects on human health when their consumption exceeds certain limits. The toxicity of these flavanoids can be attributed to the formation of reactive oxygen species in the body which causes damage to the DNA, lipid membranes etc. The aim of this review is to summarize briefly, the less studied evidences of various forms of toxicity associated with tea and its harmful effects on human health.
authors.affiliation: Department of Biotechnology, Jaypee Institute of Information Technology, A-10, Sector-62, Noida 201307, Uttar Pradesh, India.
authors.forename: Aditi
authors.initials: A
authors.lastname: Jain
authors.forename: Chanchal
authors.initials: C
authors.lastname: Manghani
authors.forename: Shrey
authors.initials: S
authors.lastname: Kohli
authors.forename: Darshika
authors.initials: D
authors.lastname: Nigam
authors.forename: Vibha
authors.initials: V
authors.lastname: Rani
mesh_terms: D002462:Cell Membrane / Q000187:drug effects; D004247:DNA / Q000187:drug effects; D004249:DNA Damage; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D018384:Oxidative Stress / Q000187:drug effects; D059808:Polyphenols / Q000009:adverse effects / Q000032:analysis; D017382:Reactive Oxygen Species; D013662:Tea / Q000009:adverse effects* / Q000737:chemistry
chemical_list: D059808:Polyphenols; D017382:Reactive Oxygen Species; D013662:Tea; D004247:DNA