title: A computational framework for ultra-high resolution cortical segmentation at 7Tesla.
abstract: This paper presents a computational framework for whole brain segmentation of 7Tesla magnetic resonance images able to handle ultra-high resolution data. The approach combines multi-object topology-preserving deformable models with shape and intensity atlases to encode prior anatomical knowledge in a computationally efficient algorithm. Experimental validation on simulated and real brain images shows accuracy and robustness of the method and demonstrates the benefits of an increased processing resolution.
authors.affiliation: Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany. Electronic address: bazin@cbs.mpg.edu.
authors.forename: Pierre-Louis
authors.initials: PL
authors.lastname: Bazin
authors.affiliation: Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
authors.forename: Marcel
authors.initials: M
authors.lastname: Weiss
authors.affiliation: Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
authors.forename: Juliane
authors.initials: J
authors.lastname: Dinse
authors.affiliation: Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Schäfer
authors.affiliation: Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
authors.forename: Robert
authors.initials: R
authors.lastname: Trampel
authors.affiliation: Department of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
authors.forename: Robert
authors.initials: R
authors.lastname: Turner
mesh_terms: D001921:Brain / Q000033:anatomy & histology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000033:anatomy & histology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging
keywords: 7Tesla MRI; Ultra-high resolution; Whole brain segmentation