title: Effectiveness of transoral laser microsurgery for precancerous lesions and early glottic cancer guided by analysis of voice quality.
abstract: BACKGROUND
  The purpose of this study was to show our comparison of the quality of voice obtained after superficial transoral endoscopic cordectomies (types I, II, and III) according to the European Laryngological Society classification versus the more extended cordectomy (types IV and V) among patients with glottic precancerous lesions or early glottic cancer.
  
  
  METHODS
  Sixty-two patients underwent vocal assessment after cordectomy (types I-V) for dysplasia, Tis, T1a, T1b, and T2 lesions.
  
  
  RESULTS
  Cordectomy (types I-III) had good vocal outcomes. Cordectomy (types IV-V) showed less favorable outcomes, p < .005 in common parameters of voice range profile and symmetry in stroboscopy after cordectomy (types IV-V), with significant voice handicap index. Recurrences were found in 4 patients with T1b and T2 cancer. Two cases were managed by a higher type of cordectomy, and the other 2 by total laryngectomy.
  
  
  CONCLUSIONS
  Effect of transoral laser microsurgery on quality of voice depends on the type of cordectomy and the site of the lesion.
authors.affiliation: Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Motol, First Faculty of Medicine, Charles University, Prague, Czech Republic.
authors.forename: Abdulrahman Ali
authors.initials: AA
authors.lastname: Bahannan
authors.forename: Aleš
authors.initials: A
authors.lastname: Slavíček
authors.forename: Libor
authors.initials: L
authors.lastname: Černý
authors.forename: Jan
authors.initials: J
authors.lastname: Vokřal
authors.forename: Zdenek
authors.initials: Z
authors.lastname: Valenta
authors.forename: Radka
authors.initials: R
authors.lastname: Lohynska
authors.forename: Martin
authors.initials: M
authors.lastname: Chovanec
authors.forename: Jan
authors.initials: J
authors.lastname: Betka
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D042241:Early Diagnosis; D005260:Female; D005931:Glottis / Q000473:pathology; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D007828:Laryngoscopy / Q000379:methods; D053685:Laser Therapy / Q000379:methods; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D049489:Stroboscopy; D016896:Treatment Outcome; D014827:Vocal Cords / Q000473:pathology; D014833:Voice Quality
keywords: cordectomy; glottic cancer; larynx; precancerous lesion; voice analysis