title: X-ray structure analysis of a solid solution of milbemycins A3 and A4.
abstract: Milbemycins A3 and A4 are pharmaceutically and agriculturally useful macrolides isolated from Streptomyces species. The molecular structures of the title compounds were unambiguously established by a single crystal X-ray analysis of the solid solution of both compounds. The crystals present trigonal system, space group P32 with Z = 3, unit cell dimensions: a = 12.2211(4), c = 17.5372(7) Å; V = 2268.4(1) Å(3), μ = 0.082 mm(- 1); d = 1.183 g cm(- 3). An interesting system of intramolecular hydrogen bonds and weak intermolecular CH…O type hydrogen bond was observed in the solid state.
authors: a Faculty of Material Science and Applied Chemistry, Riga Technical University , Azenes Str. 14/24, Riga , LV-1007 , Latvia.
authors: E
authors: E
authors: Bizdena
authors: S
authors: S
authors: Belyakov
authors: M
authors: M
authors: Jure
authors: I
authors: I
authors: Grinsteine
authors: V
authors: V
authors: Kumpiņš
authors: M
authors: M
authors: Turks
mesh_terms: D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D018942:Macrolides / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure
chemical_list: D018942:Macrolides; C027837:moxidectin