title: [State of succinate dehydrogenase in the organism--"unbalanced" or hyperactive].
abstract: Through the use of the original cytobiochemical method to study oxidation in mitochondria, preserving their native organization in network within cells in a blood smear, we revealed hyperactive state of succinate dehydrogenase, which is realized in the organism under physiological stress. It is consistent with the view of the non-equilibrium state of enzymes during activity. The mechanism of the succinate dehydrogenase hyperactivity moderation is based on the full functioning of alpha-ketoglutarate dehydrogenase, supported by oxidation of isocitric acid.
authors: M N
authors: MN
authors: Kondrashova
authors: M V
authors: MV
authors: Zakharchenko
authors: N V
authors: NV
authors: Khunderiakova
authors: N I
authors: NI
authors: Fedotcheva
authors: E G
authors: EG
authors: Litvinova
authors: O I
authors: OI
authors: Romanova
authors: A A
authors: AA
authors: Guliaev
mesh_terms: D000220:Adaptation, Biological; D008214:Lymphocytes / Q000737:chemistry / Q000166:cytology / Q000378:metabolism; D008928:Mitochondria / Q000737:chemistry / Q000502:physiology; D010084:Oxidation-Reduction; D018384:Oxidative Stress; D013385:Succinate Dehydrogenase / Q000097:blood / Q000737:chemistry / Q000378:metabolism
chemical_list: D013385:Succinate Dehydrogenase