title: Total laparoscopic radical trachelectomy in the treatment of early squamous cell cervical cancer: a retrospective study with 8-year follow-up.
abstract: OBJECTIVE
  The objective of this study was to evaluate the surgical, oncologic, and obstetrical outcomes of total laparoscopic radical trachelectomy (LRT) in patients with early-stage squamous cell cervical cancer who want to preserve their fertility.
  
  
  METHODS
  Twenty-five patients with early-stage cervical cancer were treated by total LRT from January 2005 to December 2012. Data regarding operational time, blood loss, intraoperative-and post-operative complications, recurrence, and subsequent pregnancies were recorded. Other published reports on LRT were also reviewed.
  
  
  RESULTS
  The median age of the patients was 29 years (range 22-34 years). The median surgical time was 232 min (range, 180-340 min). The median blood loss was 120 ml (range, 50-200 ml), and the median length of hospitalization was 3.3 days (range, 2-4 days). The median time to return to daily activities was 2 days (range, 1-3 days). No intra-operative complications occurred; three patients had post-operative complications. The median follow-up time was 66 months (range, 1-82 months), and no recurrences were observed. Twelve patients attempted to conceive during the follow-up, and nine succeeded.
  
  
  CONCLUSIONS
  In this retrospective analysis, total LRT was an effective and safe procedure for patients with early-stage cervical carcinoma who wished to preserve fertility. A larger prospective study with long-term pregnancy and survival analyses is warranted.
authors: Department of Obstetrics and Gynecology, Chao-yang Hospital, Capital Medical University, Beijing, China.
authors: Qi
authors: Q
authors: Lu
authors: Yunhe
authors: Y
authors: Zhang
authors: Chongdong
authors: C
authors: Liu
authors: Shuzhen
authors: S
authors: Wang
authors: Shuli
authors: S
authors: Guo
authors: Zhenyu
authors: Z
authors: Zhang
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005260:Female; D059247:Fertility Preservation; D005500:Follow-Up Studies; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008197:Lymph Node Excision; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*
keywords: Cervical cancer; Laparoscopic; Radical trachelectomy