title: Occupational risk and chronic kidney disease: a population-based study in the United States adult population.
abstract: OBJECTIVE
  Previous studies on occupational risk for chronic kidney disease (CKD) have analyzed a limited range of occupations and focused on nephrotoxins. The primary purpose of this study was to examine the relative risk for the occurrence of CKD between different occupations in the US adult population.
  
  
  METHODS
  This was a population-based survey study of 91,340 participants in the US, who completed the National Health Interview Survey, 2004 through 2008. The outcome variable, CKD, was defined as having weakening/failing kidneys in the past 12 months, as diagnosed by a physician. The predictor variable, occupation, was obtained using the census occupational codes, regrouped according to North American Industrial Classification System.
  
  
  RESULTS
  After controlling for age, gender, hypertension, and education, and with the category Life, Physical, and Social Science Occupations as a reference group, the likelihood of developing CKD was 4.3 times higher in respondents working in Building, Grounds Cleaning and Maintenance Occupations, 4.4 times higher in Healthcare Practitioners and Technical Occupations, 4.7 times higher in Transportation and Material Moving Occupations and in Computer and Mathematical Occupations, 4.8 times higher in Production Occupations, 5.3 times higher in Food Preparation and Serving Related Occupations, and 6.1 times higher in Healthcare Support Occupations and in Legal Occupations.
  
  
  CONCLUSIONS
  This study identified occupation groups in US adult population with increased risk for CKD. Alleviation of workplace stress is suggested as a goal for behavioral intervention in high-risk occupations.
authors: Department of Medicine, Nassau University Medical Center, East Meadow, NY, USA;
authors: Sofia
authors: S
authors: Rubinstein
authors: Chengwei
authors: C
authors: Wang
authors: Wenchun
authors: W
authors: Qu
keywords: CKD; occupations; risk factors
references: JAMA. 2007 Nov 7;298(17):2038-47
references: 17986697
references: Arch Environ Health. 1984 May-Jun;39(3):225-30
references: 6380428
references: Int J Epidemiol. 1995 Apr;24(2):427-34
references: 7635606
references: Int Arch Occup Environ Health. 2000 May;73(4):255-62
references: 10877031
references: Am J Ind Med. 2003 May;43(5):461-82
references: 12704620
references: Soc Sci Med. 2007 Aug;65(4):809-21
references: 17499411
references: Am J Ind Med. 1995 Apr;27(4):451-70
references: 7793419
references: Curr Opin Nephrol Hypertens. 2012 Jan;21(1):46-51
references: 22080859
references: Am J Ind Med. 1995 Feb;27(2):195-205
references: 7755010
references: Hypertension. 2011 Apr;57(4):683-5
references: 21300664
references: Ren Fail. 2010;32(8):918-22
references: 20722557
references: Rural Remote Health. 2010 Apr-Jun;10(2):1388
references: 20504048
references: Soc Sci Med. 1990;30(1):83-94
references: 2106168
references: J Am Soc Nephrol. 2007 Oct;18(10):2644-8
references: 17656472
references: J Hypertens. 2009 Mar;27(3):562-6
references: 19330916
references: Nephrol Dial Transplant. 2003 Jan;18(1):82-8
references: 12480964
references: Nephrol Dial Transplant. 2008 Apr;23(4):1122-5
references: 18359871
references: Toxicol Lett. 1989 Mar;46(1-3):257-68
references: 2650032
references: Vital Health Stat 10. 1993 Jul;(186):1-67
references: 8212601
references: Lancet. 1995 Jul 1;346(8966):7-11
references: 7603180
references: Am J Ind Med. 1997 Nov;32(5):550-6
references: 9327082
references: Hypertension. 2011 Apr;57(4):846-51
references: 21300663