title: Intestinal location of necrotizing enterocolitis among infants with congenital heart disease.
abstract: OBJECTIVE
  To determine whether differences exist in the location of necrotizing enterocolitis (NEC) in infants with congenital heart disease (CHD) versus those without CHD.
  
  
  METHODS
  Retrospective cohort study utilizing 11 years of patient data. Inclusion criterion was surgical exploration for NEC. Presence or absence of CHD was determined. Surgical and/or pathology reports were reviewed to identify the location of NEC. Data were analyzed by t-tests and χ(2) analyses.
  
  
  RESULTS
  One hundred and sixty-seven patients met the inclusion criteria. CHD infants had a higher percentage of mortality. There was no difference in the location of NEC between non-CHD and CHD patients, with the predominant location being the small intestine in both. In addition, there was no difference in the location of NEC between preterm non-CHD patients and full-term CHD patients with the small intestine again being the primary site.
  
  
  CONCLUSIONS
  Despite differences in gestational age between non-CHD and CHD patients, the location of NEC in these infants did not differ.
authors: Section for Perinatal Research, The Ohio State University of College and Medicine, Columbus, OH, USA.
authors: C
authors: C
authors: Cozzi
authors: J
authors: J
authors: Aldrink
authors: K
authors: K
authors: Nicol
authors: L
authors: L
authors: Nicholson
authors: C
authors: C
authors: Cua
mesh_terms: D001017:Aortic Coarctation / Q000453:epidemiology / Q000503:physiopathology; D015897:Comorbidity; D020345:Enterocolitis, Necrotizing / Q000453:epidemiology* / Q000473:pathology* / Q000503:physiopathology; D006330:Heart Defects, Congenital / Q000453:epidemiology* / Q000503:physiopathology; D006343:Heart Septal Defects / Q000453:epidemiology; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007421:Intestine, Small / Q000473:pathology*; D012189:Retrospective Studies; D013771:Tetralogy of Fallot / Q000453:epidemiology