title: Management of neuropathic pain in children with cancer.
abstract: OBJECTIVE
  Many children with cancer suffer from neuropathic pain. However, there are no published pediatric randomized controlled trials (RCTs), nor agreed upon pediatric treatment recommendations. Pediatric neuropathic pain in patients with malignancies is often underassessed and undertreated with ineffective therapies.
  
  
  RESULTS
  This article describes main themes in the literature and commonly used treatment strategies.
  
  
  CONCLUSIONS
  A combination of integrative, rehabilitative, and supportive therapies with pharmacotherapy, including first line medications such as NSAIDs, opioids, low-dose tricyclics, and gabapentinoids, appear to be successful treatment strategies. There is a dearth of evidence regarding the management of neuropathic pain in children with cancer; studies, especially RCTs, are desperately needed.
authors: Department of Pain Medicine, Palliative Care and Integrative Medicine, Children's Hospitals and Clinics of Minnesota, Minnesota 55404, USA. stefan.friedrichsdorf@childrensMN.org
authors: Stefan J
authors: SJ
authors: Friedrichsdorf
authors: Andrea Postier
authors: AP
authors: Nugent
mesh_terms: D000700:Analgesics / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D009437:Neuralgia / Q000188:drug therapy* / Q000209:etiology / Q000628:therapy; D059408:Pain Management / Q000379:methods*; D010147:Pain Measurement / Q000379:methods; D010372:Pediatrics
chemical_list: D000700:Analgesics