title: [Profile of autonomous regulation of circulation in patients with severe left ventricular myocardial hypertension].
abstract: The possibility of concomitant hypertrophic myopathy (HCMP) and hypertensive disease (HD) in the same patient is debatable. This study aimed at estimating peculiarities of autonomous regulation of circulation and clinic-pathogenetic features of the disease in patients with marked hypertrophy of interventrucular septum (IVS) depending on the presence of arterial hypertension (AH). The patients with manifest left ventricular hypertrophy (MLVH) were divided into those with and without AH. Clinical examination included assessment of the vasomotor cardiopulmonary baroreflex (VM CPBR). Valsalva maneuver, sensitivity of spontaneous arterial baroreflex (ABR), cardiac rhythm variability at rest and orthostasis. Hemodynamic parameters were determined by continuous non-invasive recording using a Finometer arterial pressure monitor. Patients with HCMP showed reduced VM CPBR, preserved ABR, Valsalva and sympatovagal indices. Similar but less pronounced changes were documented in patients with MLVH, AH and HD. Profile of autonomous regulation of circulation in patients with manifest left ventricular myocardial hypertension and AH was significantly different from that in HCMP patients but similar to the profile in the patients with HD.
authors: O V
authors: OV
authors: Mamontov
authors: T A
authors: TA
authors: Liubimtseva
authors: O M
authors: OM
authors: Moiseeva
authors: O B
authors: OB
authors: Irtiuga
authors: O B
authors: OB
authors: Shliakhto
mesh_terms: D017704:Baroreflex / Q000502:physiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D017379:Hypertrophy, Left Ventricular / Q000473:pathology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index