title: Human Papillomavirus-mediated cervical cancer awareness and Gardasil vaccination: a pilot survey among North Indian women.
abstract: Human Papillomavirus (HPV)-mediated cervical cancer is a leading cause of morbidity and mortality in women worldwide, including Indian women. Cervical cancer control and prevention strategies are being adopted in developing nations to reduce the increasing burden of HPV infection in the vaccine era. The present study, therefore, aimed to evaluate cervical cancer awareness and knowledge of Gardasil vaccination in North Indian women. A pilot survey was conducted among 103 women of North Indian ethnicity residing in Lucknow/adjoining areas in state of Uttar Pradesh, during routine screening/clinic visits from June 2012 to December 2012. The study subjects were interviewed in either Hindi or English; subsequently the awareness of HPV-mediated cervical cancer and knowledge of Gardasil vaccination was assessed in terms of "yes", "no" and "no response". The study was approved by the Institutional Review Board. Written informed consent was taken from the participants. Overall, the response of participants (n = 103) in our single-centre survey-based pilot study was well-defined. The response regarding HPV-mediated cervical cancer awareness in terms of "yes", "no" and "no response" among the study subjects was 43.7, 44.7 and 11.6 %, respectively. Furthermore, in response to knowledge of HPV vaccine Gardasil, out of 103 subjects, 28.1 % answered "yes" while 37.9 and 34.0 % stated "no" and "no response", respectively. Our pilot survey may help in assessing knowledge of HPV-mediated cervical cancer and Gardasil vaccination awareness in women, and accordingly develop cost-effective cervical cancer control and prevention/public health counseling sessions in a clinical setting.
authors: Krishna Medical Centre, 1, Rana Pratap Marg, Lucknow, India. saumyapandey6@yahoo.com
authors: Saumya
authors: S
authors: Pandey
authors: Chandravati
mesh_terms: D000328:Adult; D001364:Awareness; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D000068857:Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; D006801:Humans; D007194:India / Q000453:epidemiology; D030361:Papillomavirus Infections / Q000150:complications* / Q000517:prevention & control*; D053918:Papillomavirus Vaccines / Q000008:administration & dosage*; D010865:Pilot Projects; D002583:Uterine Cervical Neoplasms / Q000209:etiology* / Q000821:virology
chemical_list: D000068857:Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; D053918:Papillomavirus Vaccines
references: World J Gastroenterol. 2005 Feb 21;11(7):931-7
references: 15742391
references: J Clin Pathol. 2002 Apr;55(4):244-65
references: 11919208
references: Cancer Prev Res (Phila). 2009 Oct;2(10):868-78
references: 19789295
references: Vaccine. 2006 Jul 7;24(27-28):5571-83
references: 16753240
references: Int J Cancer. 2000 May 1;86(3):429-35
references: 10760834
references: Lancet Oncol. 2005 May;6(5):271-8
references: 15863374
references: J Natl Cancer Inst. 2001 Feb 21;93(4):293-9
references: 11181776
references: Int J Gynecol Cancer. 2010 May;20(4):625-30
references: 20686383
references: Anticancer Res. 2000 Nov-Dec;20(6C):4673-80
references: 11205199
references: Lancet. 2009 Jul 25;374(9686):301-14
references: 19586656
references: Lancet. 2004 Nov 13-19;364(9447):1757-65
references: 15541448
references: Kobe J Med Sci. 2004 Jan;50(1-2):9-19
references: 15342967
references: Br J Cancer. 2006 Dec 4;95(11):1459-66
references: 17117182
references: Lancet. 2006 Apr 15;367(9518):1247-55
references: 16631880
references: Nat Rev Cancer. 2002 May;2(5):342-50
references: 12044010
references: Asian Pac J Cancer Prev. 2012;13(10):4867-71
references: 23244072
references: Indian J Med Res. 2009 Sep;130(3):327-33
references: 19901442
references: Reprod Health. 2005 Dec 08;2:11
references: 16336668
references: J Pathol. 1999 Sep;189(1):12-9
references: 10451482