title: Nanocrystals for the parenteral delivery of poorly water-soluble drugs.
abstract: Nanocrystals have drawn increasing interest in pharmaceutical industry because of the ability to improve dissolution of poorly water-soluble drugs. Nanocrystals can be produced by top-down and bottom-up technologies and have been explored for a variety of therapeutic applications. Here we review the methods of nanocrystal production and parenteral applications of nanocrystals. We also discuss remaining challenges in the development of nanocrystal products.
authors: Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, IN 47907, USA.
authors: Bo
authors: B
authors: Sun
authors: Yoon
authors: Y
authors: Yeo
keywords: Nanocrystals; nanosuspension; parenteral applications; poorly water-soluble drugs
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