title: Mucinous tubular and spindle cell carcinoma of the kidney with sarcomatoid transformation.
abstract: Mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney is a recently described entity in the World Health Organization (WHO) 2004 classification and has a relatively indolent behavior. Sarcomatoid differentiation has been well documented in most histologic variants of renal cell carcinoma and its presence is known to have a worse prognosis. Its occurrence in an otherwise benign MTSCC is extremely rare. Here, we report a unique case of MTSCC in a 64-year-old patient with multiple areas of high-grade spindle cells and large areas of necrosis in it. The patient had a rapidly fatal clinical outcome.
authors: Department of Histopathology, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia. marafah@hotmail.com
authors: Maha
authors: M
authors: Arafah
authors: Shaesta Naseem
authors: SN
authors: Zaidi
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D002292:Carcinoma, Renal Cell / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D002454:Cell Differentiation; D017809:Fatal Outcome; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D060787:Neoplasm Grading; D018193:Neoplasms, Complex and Mixed / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D009392:Nephrectomy; D012509:Sarcoma / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D016896:Treatment Outcome