title: Asperterpenols A and B, new sesterterpenoids isolated from a mangrove endophytic fungus Aspergillus sp. 085242.
abstract: Asperterpenol A (1) and asperterpenol B (2), two novel sesterterpenoids with an unusual 5/8/6/6 tetracyclic ring skeleton, were isolated from a mangrove endophytic fungus Aspergillus sp. 085242. The structures were elucidated on the basis of spectroscopic methods and the absolute configurations determined by single-crystal X-ray diffraction analysis. Compounds 1 and 2 inhibit acetylcholinesterase with IC50 values of 2.3 and 3.0 μM, respectively.
authors: School of Chemistry and Chemical Engineering and School of Life Sciences, Sun Yat-sen University , Guangzhou 510275, China, and School of Chemistry and Environment, South China Normal University , 348 West Outer Ring Road, Guangzhou 510006, China.
authors: Ze'en
authors: Z
authors: Xiao
authors: Huarong
authors: H
authors: Huang
authors: Changlun
authors: C
authors: Shao
authors: Xuekui
authors: X
authors: Xia
authors: Lin
authors: L
authors: Ma
authors: Xishan
authors: X
authors: Huang
authors: Yongjun
authors: Y
authors: Lu
authors: Yongcheng
authors: Y
authors: Lin
authors: Yuhua
authors: Y
authors: Long
authors: Zhigang
authors: Z
authors: She
mesh_terms: D001230:Aspergillus / Q000737:chemistry*; D018360:Crystallography, X-Ray; D005658:Fungi / Q000737:chemistry*; D015394:Molecular Structure; D054830:Sesterterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D013057:Spectrum Analysis
chemical_list: D054830:Sesterterpenes; C000588677:asperterpenol A; C000588678:asperterpenol B