title: A photoresponsive supramolecular G-quadruplex.
abstract: Photoirradiation of a hexadecameric supramolecular G-quadruplex leads to a diastereoselective [2 + 2] cyclodimerization of half of its constituent subunits, which in turn shifts the equilibrium toward the formation of a precise heteromeric octamer.
authors: Department of Chemistry, University of Puerto Rico , Río Piedras Campus, Río Piedras, Puerto Rico 00931.
authors: José M
authors: JM
authors: Rivera
authors: Diana
authors: D
authors: Silva-Brenes
mesh_terms: D002942:Circular Dichroism; D003849:Deoxyguanosine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*; D019281:Dimerization; D054856:G-Quadruplexes; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010778:Photochemotherapy; D013237:Stereoisomerism
chemical_list: C000588432:8-chalconyl-2'-deoxyguanosine; D003849:Deoxyguanosine
references: J Am Chem Soc. 2008 Aug 13;130(32):10492-3
references: 18642917
references: Chemistry. 2003 Oct 6;9(19):4771-80
references: 14566885
references: J Am Chem Soc. 2009 Mar 11;131(9):3186-8
references: 19216522
references: Langmuir. 2011 Feb 15;27(4):1409-14
references: 21117678
references: Org Biomol Chem. 2012 Oct 7;10(37):7562-5
references: 22895684
references: Chem Soc Rev. 2008 Aug;37(8):1520-9
references: 18648678
references: Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):4801-4
references: 11880602
references: Acc Chem Res. 2008 Feb;41(2):280-91
references: 18281948
references: Chem Soc Rev. 2007 Jan;36(1):77-92
references: 17173147
references: Nat Chem. 2009 May;1(2):151-5
references: 21378828
references: Org Lett. 2004 Dec 9;6(25):4735-8
references: 15575673
references: J Am Chem Soc. 2009 Aug 5;131(30):10403-5
references: 19722619
references: Chem Rev. 2006 Dec;106(12):5413-30
references: 17165693
references: J Am Chem Soc. 2003 Apr 23;125(16):4831-5
references: 12696902
references: Angew Chem Int Ed Engl. 2012 Sep 17;51(38):9679-83
references: 22930664
references: Org Lett. 2008 Jun 5;10(11):2287-90
references: 18452304
references: Angew Chem Int Ed Engl. 2010 May 10;49(21):3657-60
references: 20391448
references: J Am Chem Soc. 2009 Nov 25;131(46):16666-8
references: 19883053
references: Angew Chem Int Ed Engl. 2006 Jul 10;45(28):4601-4
references: 16791899
references: Angew Chem Int Ed Engl. 2005 Feb 4;44(7):1072-1075
references: 15645443
references: Org Lett. 2006 Dec 21;8(26):6051-4
references: 17165927
references: J Am Chem Soc. 2009 Jun 3;131(21):7247-9
references: 19432432
references: J Am Chem Soc. 2010 Sep 29;132(38):13434-42
references: 20815400
references: J Am Chem Soc. 2004 Sep 22;126(37):11500-8
references: 15366895
references: Chem Rev. 2011 Sep 14;111(9):5784-814
references: 21846150
references: Chem Commun (Camb). 2011 Dec 14;47(46):12485-7
references: 22022705
references: Photochem Photobiol Sci. 2011 Jan;10(1):15-8
references: 20976366