title: Subjectively impaired bed mobility in Parkinson disease affects sleep efficiency.
abstract: BACKGROUND
  Impaired bed mobility (IBM) may be an important reason for the high prevalence of sleep insomnia in Parkinson disease (PD). Here we assessed the influence of subjectively IBM on both subjective and objective sleep parameters in insomnia PD patients with (PD+IBM) and without (PD-IBM) concerns of IBM and controls with primary insomnia.
  
  
  METHODS
  We included 44 PD patients with sleep initiation or maintenance concerns and 44 control subjects with primary insomnia. Sleep questionnaires, polysomnographic sleep parameters, activity data, and the number of body position changes were compared between PD patients and controls as well as within the PD group between PD+IBM vs PD-IBM subjects.
  
  
  RESULTS
  There were 54.5% of PD subjects who reported having IBM. In the PD+IBM group, the number of body position changes was significantly lower than in PD-IBM (0.4/h [0.0-1.8] vs 1.4/h [0.0-4.6], P=.015). Sleep efficiency (SE) was lower in PD+IBM patients (63.5; 26.2-85.6) compared to PD-IBM patients (78.4; 54.8-92.6; P<.001).
  
  
  CONCLUSIONS
  PD patients who report IBM have fewer sleep-related body position changes (i.e., nocturnal hypokinesia) than PD patients without such concerns. Furthermore, objective SE is significantly diminished in these patients.
authors: Sleep Medicine Centre Kempenhaeghe, Heeze, The Netherlands.
authors: Maartje
authors: M
authors: Louter
authors: Ruud J G
authors: RJ
authors: van Sloun
authors: Dirk A A
authors: DA
authors: Pevernagie
authors: Johan B A M
authors: JB
authors: Arends
authors: Pierre J
authors: PJ
authors: Cluitmans
authors: Bastiaan R
authors: BR
authors: Bloem
authors: Sebastiaan
authors: S
authors: Overeem
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001510:Bed Rest; D005260:Female; D006801:Humans; D018476:Hypokinesia / Q000453:epidemiology* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000453:epidemiology* / Q000503:physiopathology*; D056888:Patient Positioning; D017286:Polysomnography; D015995:Prevalence; D012890:Sleep / Q000502:physiology; D007319:Sleep Initiation and Maintenance Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology*; D011795:Surveys and Questionnaires
keywords: Bed mobility; Hypokinesia; Parkinson’s disease; Sleep disorders; Sleep efficiency; Sleep quality