title: [Diagnosis and treatment of adipsic diabetes insipidus accompanied with intracranial calcification].
abstract: OBJECTIVE
  To summarize our experience in the management of adipsic central diabetes insipidus(ADI) accompanied with intracranial calcification.
  
  
  METHODS
  The clinical data of one ADI patient accompanied with intracranial calcification who was treated in our hospital since December 2011 were retrospectively summarized.
  
  
  RESULTS
  The 24-hour urine volume was 800 ml. She didn't feel thirsty even with increased plasma sodium concentration(153 mmol/L) and blood osmotic pressure(333 mmol/L) . Combined water deprivation and vasopressin test revealed the diagnosis of central diabetes insipidus. The high intensity signal(on T1-weighted magnetic resonance imaging) in the posterior lobe of pituitary gland was found. Computed tomography showed calcifications in the bilateral basal ganglia.Serum cytomegalovirus IgG was positive. She was treated with desmopressin and asked for regular water intake regardless of the adipsia. The plasma sodium concentration was still below 150 mmol/L during the 4-month follow-up.
  
  
  CONCLUSIONS
  Routine adipsia evaluation and combined water deprivation and vasopressin test are critical for the diagnosis and treatment of ADI. Past insidious intracranial cytomegalovirus infection may explain the cause of ADI and calcification.
authors: Department of Endocrinology, PUMC Hospital, CAMS and PUMC, Beijing, China.
authors: Ming-ming
authors: MM
authors: Hu
authors: Min
authors: M
authors: Liu
authors: Wei
authors: W
authors: Liu
mesh_terms: D001927:Brain Diseases / Q000150:complications*; D002114:Calcinosis / Q000150:complications*; D002648:Child; D003587:Cytomegalovirus; D020790:Diabetes Insipidus, Neurogenic / Q000150:complications* / Q000175:diagnosis* / Q000209:etiology; D004326:Drinking; D005260:Female; D006801:Humans; D012964:Sodium / Q000097:blood
chemical_list: D012964:Sodium