title: Hip and knee replacement in the HIV positive patient.
abstract: Arthroplasty is used to relieve pain associated with degenerative or inflammatory joint disease, some post-traumatic joint problems, and avascular necrosis. Avascular necrosis, inflammatory and post-traumatic problems are seen on a regular basis in areas of high HIV seroprevalence. Degenerative arthritis is rare in younger HIV patients, however. Historically the only group of HIV patients in which arthroplasty has been common is that which received contaminated factor VIII transfusions in the 1980's. Haemophiliacs get a haemophilic arthropathy from repeated bleeds into joints and so is an additional complication. Much of the previous literature on this topic has focused on haemophiliac patients. This review examines the success of arthroplasty in HIV positive patients, with an emphasis on non-haemophiliac patients. We conclude that arthroplasty can be a safe procedure for HIV positive individuals if the surgery is carried out in good conditions, and early results are encouraging.
authors: St John's College, Cambridge, CB2 1TP (both contributed equally).
authors: E R
authors: ER
authors: Anand
authors: L A
authors: LA
authors: Scott
authors: W J
authors: WJ
authors: Harrison
mesh_terms: D023241:Antiretroviral Therapy, Highly Active / Q000379:methods; D019644:Arthroplasty, Replacement, Hip; D019645:Arthroplasty, Replacement, Knee; D006679:HIV Seropositivity / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D016896:Treatment Outcome
references: J Bone Joint Surg Br. 2005 Sep;87(9):1178-81
references: 16129738
references: J Bone Joint Surg Br. 2009 Mar;91(3):341-3
references: 19258609
references: Int Orthop. 1996;20(4):253-6
references: 8872550
references: J Bone Joint Surg Br. 1993 May;75(3):368-70
references: 8098712
references: J Bone Joint Surg Am. 2003 May;85(5):969; author reply 969-70
references: 12728056
references: Chin Med J (Engl). 2004 Sep;117(9):1437-40
references: 15377446
references: J Bone Joint Surg Br. 2002 Aug;84(6):802-6
references: 12211668
references: J Bone Joint Surg Br. 2001 Sep;83(7):1050-4
references: 11603522
references: Science. 1996 Jan 19;271(5247):324-8
references: 8553066
references: J Arthroplasty. 1995 Dec;10(6):716-21
references: 8749751
references: Clin Orthop Relat Res. 1999 Mar;(360):169-73
references: 10101322
references: J Bone Joint Surg Am. 2002 Jul;84(7):1138-41
references: 12107312