title: Optical imaging of non-fluorescent nanodiamonds in live cells using transient absorption microscopy.
abstract: We directly observe non-fluorescent nanodiamonds in living cells using transient absorption microscopy. This label-free technology provides a novel modality to study the dynamic behavior of nanodiamonds inside the cells with intrinsic three-dimensional imaging capability. We apply this method to capture the cellular uptake of nanodiamonds under various conditions, confirming the endocytosis mechanism.
authors: Biodynamic Optical Imaging Center (BIOPIC), College of Engineering, Peking University, Beijing, China.
authors: Tao
authors: T
authors: Chen
authors: Feng
authors: F
authors: Lu
authors: Aaron M
authors: AM
authors: Streets
authors: Peng
authors: P
authors: Fei
authors: Junmin
authors: J
authors: Quan
authors: Yanyi
authors: Y
authors: Huang
mesh_terms: D000818:Animals; D006367:HeLa Cells; D006801:Humans; D051379:Mice; D008856:Microscopy, Fluorescence; D041681:NIH 3T3 Cells; D058612:Nanodiamonds / Q000737:chemistry* / Q000648:ultrastructure
chemical_list: D058612:Nanodiamonds