title: FDA moves on breakthrough therapies.
authors: Jeffrey L
authors: JL
authors: Fox
mesh_terms: D000627:Aminophenols / Q000627:therapeutic use*; D000631:Aminopyridines / Q000627:therapeutic use*; D052117:Benzodioxoles / Q000627:therapeutic use*; D017277:Drug Approval / Q000458:organization & administration*; D009369:Neoplasms / Q000188:drug therapy*; D015363:Quinolones / Q000627:therapeutic use*; D013727:Terminal Care / Q000639:trends*; D014481:United States
chemical_list: D000627:Aminophenols; D000631:Aminopyridines; D052117:Benzodioxoles; D015363:Quinolones; C545203:ivacaftor; C569105:lumacaftor
references: Nat Biotechnol. 2012 Aug;30(8):733-4
references: 22871697