title: [Optical coherence tomography. Bases and applications of a new intravascular imaging technique].
abstract: Coronary angiography is the reference technique for the diagnosis of coronary disease. However, the majority of acute coronary syndromes involve angiographically non-significant lesions. It is also the technique of choice for guiding the implantation of endovascular prostheses and their later monitoring. Optical coherence tomography is an interferometric imaging technique that penetrates tissue approximately 2-3mm and provides axial and lateral resolution. It is able to distinguish different tissue types, such as fibrous, lipid-rich, necrotic, or calcified tissue. Optical coherence tomography is able to recognize a variety of features of atherosclerotic plaques that have been associated with rapid lesion progression and clinical events, such as thin cap fibroatheroma, fibrous cap thickness, dense macrophage infiltration, and thrombus formation. Currently, there is growing interest in the value of optical coherence tomography in the area of coronary intervention, where the technique offers significant advantages over more widespread intravascular diagnostic techniques such as intravascular ultrasound. Its higher resolution permits to recognize periprocedural complications, such as microdissection of the coronary artery, stent malapposition, and neointimal hyperplasia, making this tool one of the most promising techniques in the intravascular diagnosis.
authors: Servicio de Hemodinámica, Departamento de Cardiología Intervencionista, Hospital Universitario Clínico San Carlos, Madrid, España. Electronic address: enricomacias@hotmail.com.
authors: Enrico
authors: E
authors: Macías
authors: Miguel Ángel
authors: MÁ
authors: Medina
authors: Nieves
authors: N
authors: Gonzalo
authors: Juan
authors: J
authors: del Angel
authors: Javier
authors: J
authors: Escaned
mesh_terms: D003324:Coronary Artery Disease / Q000473:pathology* / Q000601:surgery; D023921:Coronary Stenosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D058226:Plaque, Atherosclerotic / Q000473:pathology* / Q000601:surgery; D012008:Recurrence; D012720:Severity of Illness Index; D015607:Stents; D041623:Tomography, Optical Coherence / Q000379:methods