title: Pregnancy and hemolysis, elevated liver enzymes and low platelet count syndrome in patients with Eisenmenger's syndrome.
abstract: Eisenmenger's syndrome is characterized by a right-to-left or bidirectional shunt in congenital heart diseases. Hemolysis, elevated liver enzymes and low platelet count (HELLP) syndrome, commonly occurring during pregnancy, includes hemolysis, elevated liver enzymes and low platelet counts. HELLP syndrome and pregnancy are extremely rare in patients with Eisenmenger's syndrome. The authors report 4 cases of pregnancy complicated by the HELLP and Eisenmenger's syndrome and describe their initial intervention and the in-hospital outcomes of these cases. Special emphasis is given to elaborate about the hemodynamic monitoring, magnesium sulphate for convulsions, corticosteroid treatment, anticoagulation therapy, management of pulmonary hypertension, the timing of delivery, and blood product transfusion.
authors: Department of Obstetrics and Gynecology, Beijing Anzhen Hospital of Capital Medical University, Beijing, China.
authors: Hong
authors: H
authors: Wang
authors: Tao
authors: T
authors: Liu
mesh_terms: D000305:Adrenal Cortex Hormones / Q000494:pharmacology / Q000627:therapeutic use; D000328:Adult; D000925:Anticoagulants / Q000494:pharmacology / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000494:pharmacology / Q000627:therapeutic use; D019468:Disease Management; D004541:Eisenmenger Complex / Q000150:complications* / Q000503:physiopathology; D017809:Fatal Outcome; D005260:Female; D005313:Fetal Death; D017359:HELLP Syndrome / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D011256:Pregnancy Outcome; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; D000925:Anticoagulants; D000959:Antihypertensive Agents