title: [Antithrombotic drug and gastrointestinal injuries].
abstract: Gastrointestinal injuries induced by anti-coagulant agents, especially low-dose aspirin (LDA) increased. Concomitant usage of LDA and NSAIDs, LDA and anti-coagulant are risk factor of upper gastrointestinal (UGI)-bleeding. Time of UGI-bleeding occurred in early periods after starting of LDA and NSAIDs. H. pylori infection and LDA interact synergic and negative synergic with reference to gastric mucosal injury.
authors: Endoscopic Center, Tokyo Medical University Hospital.
authors: Takashi
authors: T
authors: Kawai
authors: Mari
authors: M
authors: Fukuzawa
authors: Fuminori
authors: F
authors: Moriyasu
authors: Akira
authors: A
authors: Yamashina
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000627:therapeutic use; D001241:Aspirin / Q000009:adverse effects* / Q000627:therapeutic use; D005343:Fibrinolytic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced*; D016481:Helicobacter Infections / Q000188:drug therapy*; D006801:Humans; D012307:Risk Factors
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005343:Fibrinolytic Agents; D001241:Aspirin