title: Enantioselective nickel-catalyzed Michael additions of 2-acetylazaarenes to nitroalkenes.
abstract: 2-Acetylazaarenes undergo catalytic enantioselective Michael additions to nitroalkenes in the presence of a chiral Ni(II)-bis(oxazoline) complex. The process is tolerant of a range of azines or azoles in the pronucleophilic component, resulting in Michael products in moderate to high enantioselectivities.
authors: EaStCHEM, School of Chemistry, University of Edinburgh , Joseph Black Building, The King's Buildings, West Mains Road, Edinburgh, EH9 3JJ, United Kingdom.
authors: Alain J
authors: AJ
authors: Simpson
authors: Hon Wai
authors: HW
authors: Lam
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D001372:Aza Compounds / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D015394:Molecular Structure; D009532:Nickel / Q000737:chemistry*; D009574:Nitro Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D000475:Alkenes; D001372:Aza Compounds; D009574:Nitro Compounds; D009532:Nickel