title: Severe fever with thrombocytopenia syndrome virus among domesticated animals, China.
abstract: To investigate the infections of severe fever with thrombocytopenia syndrome virus (SFTSV) in domesticated animals, we sampled a total of 3,039 animals in 2 counties in Shandong Province, People's Republic of China, from April to November 2011. SFTSV-specific antibodies were detected in 328 (69.5%) of 472 sheep, 509 (60.5%) of 842 cattle, 136 (37.9%) of 359 dogs, 26 (3.1%) of 839 pigs, and 250 (47.4%) of 527 chickens. SFTSV RNA was detected in all sampled animal species, but the prevalence was low, ranging from 1.7% to 5.3%. A cohort study in 38 sheep was conducted to determine when seroconversion to SFTSV occured. SFTSVs were isolated from sheep, cattle, and dogs and shared >95% sequence homology with human isolates from the same disease-endemic regions. These findings demonstrate that natural infections of SFTSV occur in several domesticated animal hosts in disease-endemic areas and that the virus has a wide host range.
authors: Key Laboratory for Medical Virology–Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China.
authors: Guoyu
authors: G
authors: Niu
authors: Jiandong
authors: J
authors: Li
authors: Mifang
authors: M
authors: Liang
authors: Xiaolin
authors: X
authors: Jiang
authors: Mei
authors: M
authors: Jiang
authors: Haiying
authors: H
authors: Yin
authors: Zhidian
authors: Z
authors: Wang
authors: Chuan
authors: C
authors: Li
authors: Quanfu
authors: Q
authors: Zhang
authors: Cong
authors: C
authors: Jin
authors: Xianjun
authors: X
authors: Wang
authors: Shujun
authors: S
authors: Ding
authors: Zheng
authors: Z
authors: Xing
authors: Shiwen
authors: S
authors: Wang
authors: Zhenqiang
authors: Z
authors: Bi
authors: Dexin
authors: D
authors: Li
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood* / Q000276:immunology; D002044:Bunyaviridae Infections / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary* / Q000821:virology; D002417:Cattle; D002645:Chickens / Q000821:virology; D002681:China / Q000453:epidemiology; D004285:Dogs; D006801:Humans; D016856:Phlebovirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D010802:Phylogeny; D015995:Prevalence; D012367:RNA, Viral / Q000097:blood / Q000145:classification / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D034561:Sheep, Domestic / Q000821:virology; D013552:Swine / Q000821:virology; D015047:Zoonoses / Q000453:epidemiology* / Q000635:transmission / Q000821:virology
chemical_list: D000914:Antibodies, Viral; D012367:RNA, Viral
keywords: China; Phlebovirus; SFTSV; domesticated animals; family Bunyaviridae; host; infection; pathogenic disease; prevalence; severe fever with thrombocytopenia syndrome virus; transmission; viruses; zoonoses
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