title: Pituitary ischemic apoplexy in a young woman using oral contraceptives: a case report.
abstract: Estrogen is suggested to be one of the plausible risk factors for pituitary hemorrhagic apoplexy through pituitary hyperemia. We experienced a 33-year-old woman with pituitary ischemic apoplexy of a nonfunctional macroadenoma under oral contraceptive use. Our case indicates that hypercoagulable state, but not hyperemia, associated with estrogen may promote pituitary ischemic apoplexy.
authors: Division of Cerebrovascular Medicine, Department of Stroke and Cerebrovascular Diseases, National Cerebral and Cardiovascular Center, Osaka. Electronic address: junpei@hsp.ncvc.go.jp.
authors: Junpei
authors: J
authors: Kobayashi
authors: Kotaro
authors: K
authors: Miyashita
authors: Tamiko
authors: T
authors: Tamanaha
authors: Norikata
authors: N
authors: Kobayashi
authors: Koji
authors: K
authors: Iihara
authors: Kazuyuki
authors: K
authors: Nagatsuka
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D001777:Blood Coagulation / Q000187:drug effects; D003277:Contraceptives, Oral, Combined / Q000009:adverse effects*; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010899:Pituitary Apoplexy / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D010911:Pituitary Neoplasms / Q000150:complications* / Q000175:diagnosis; D011237:Predictive Value of Tests; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D003277:Contraceptives, Oral, Combined; D003278:Contraceptives, Oral, Hormonal
keywords: Pituitary; corticotropin; estrogen; headache; thyrotropin