title: SAPs as novel regulators of abiotic stress response in plants.
abstract: Stress associated proteins (SAPs), novel A20/AN1 zinc-finger domain-containing proteins, are fast emerging as potential candidates for biotechnological approaches in order to improve abiotic stress tolerance in plants - the ultimate aim of which is crop-yield protection. Until relatively recently, such proteins had only been identified in humans, where they had been shown to be key regulators of innate immunity. Their phylogenetic relationship and recruitment of diverse protein domains reflect an architectural and mechanistic diversity. Emerging evidence suggests that SAPs may act as ubiquitin ligase, redox sensor, and regulator of gene expression during stress. Here, we evaluate the new knowledge on SAPs with a view to understand their mechanism of action. Furthermore, we set an agenda for investigating hitherto unexplored roles of these proteins.
authors: National Institute of Plant Genome Research, New Delhi, India.
authors: Jitender
authors: J
authors: Giri
authors: Prasant K
authors: PK
authors: Dansana
authors: Kamakshi S
authors: KS
authors: Kothari
authors: Gunjan
authors: G
authors: Sharma
authors: Shubha
authors: S
authors: Vij
authors: Akhilesh K
authors: AK
authors: Tyagi
mesh_terms: D000818:Animals; D018506:Gene Expression Regulation, Plant; D017343:Genes, Plant; D006360:Heat-Shock Proteins / Q000235:genetics / Q000378:metabolism*; D005810:Multigene Family; D010802:Phylogeny; D018521:Plant Physiological Phenomena; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D017434:Protein Structure, Tertiary / Q000235:genetics; D015398:Signal Transduction; D013312:Stress, Physiological; D044767:Ubiquitin-Protein Ligases / Q000235:genetics / Q000378:metabolism; D016335:Zinc Fingers / Q000235:genetics
chemical_list: D006360:Heat-Shock Proteins; D010940:Plant Proteins; D044767:Ubiquitin-Protein Ligases