title: Sepsis caused by Mycobacterium terrae complex in a patient with sickle cell disease.
abstract: Infections are a significant cause of morbidity and mortality in patients with sickle cell disease. Loss of splenic function in these patients makes them highly susceptible to some bacterial infections. Non-tuberculous mycobacterial infections in patients with sickle cell disease are extremely rare and only two cases have been reported previously. We describe a case of sepsis caused by non-tuberculous mycobacterium, Mycobacterium terrae complex in a patient with febrile sickle cell disease. M terrae complex is a rare clinical pathogen and this is the first reported case of sepsis secondary to this organism in a patient with sickle cell disease. The patient responded to imipenem and amikacin therapy.
authors: Department of Pathology, Howard University Hospital, Washington, DC, USA. aesnakula@howard.edu
authors: Ashwini K
authors: AK
authors: Esnakula
authors: Sudhir K
authors: SK
authors: Mummidi
authors: Patricia A
authors: PA
authors: Oneal
authors: Tammey J
authors: TJ
authors: Naab
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D009170:Nontuberculous Mycobacteria; D018805:Sepsis / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents
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