title: Use of high-frequency jet ventilation for percutaneous tumor ablation.
abstract: OBJECTIVE
  To report feasibility and potential benefits of high-frequency jet ventilation (HFJV) in tumor ablations techniques in liver, kidney, and lung lesions.
  
  
  METHODS
  This prospective study included 51 patients (14 women, mean age 66 years) bearing 66 tumors (56 hepatic, 5 pulmonary, 5 renal tumors) with a median size of 16 ± 8.7 mm, referred for tumor ablation in an intention-to-treat fashion before preoperative anesthesiology visit. Cancellation and complications of HFJV were prospectively recorded. Anesthesia and procedure duration, as well as mean CO2 capnea, were recorded. When computed tomography guidance was used, 3D spacial coordinates of an anatomical target <2 mm in diameter on 8 slabs of 4 slices of 3.75-mm slice thickness were registered.
  
  
  RESULTS
  HFJV was used in 41 of 51 patients. Of the ten patients who were not candidate for HFJV, two patients had contraindication to HFJV (severe COPD), three had lesions invisible under HFJV requiring deep inspiration apnea for tumor targeting, and five patients could not have HFJV because of unavailability of a trained anesthetic team. No specific complication or hypercapnia related to HFJV were observed despite a mean anesthetic duration of 2 h and ventilation performed in procubitus (n = 4) or lateral decubitus (n = 6). Measured internal target movement was 0.3 mm in x- and y-axis and below the slice thickness of 3.75 mm in the z-axis in 11 patients.
  
  
  CONCLUSIONS
  HFJV is feasible in 80 % of patients allowing for near immobility of internal organs during liver, kidney, and lung tumor ablation.
authors: Department of Radiology and Interventional Radiology, Lausanne University Hospital, 46 rue du Bugnon, 1011, Lausanne, Switzerland, alban.denys@chuv.ch.
authors: Alban
authors: A
authors: Denys
authors: Yann
authors: Y
authors: Lachenal
authors: Rafael
authors: R
authors: Duran
authors: Madeleine
authors: M
authors: Chollet-Rivier
authors: Pierre
authors: P
authors: Bize
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017115:Catheter Ablation / Q000295:instrumentation*; D003287:Contrast Media / Q000008:administration & dosage; D004867:Equipment Design; D005240:Feasibility Studies; D005260:Female; D006611:High-Frequency Jet Ventilation / Q000295:instrumentation*; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015641:Radiography, Interventional; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media