title: Admission hyperglycemia predicts inhospital mortality and major adverse cardiac events after primary percutaneous coronary intervention in patients without diabetes mellitus.
abstract: Admission hyperglycemia is associated with high inhospital and long-term adverse events in patients that undergo primary percutaneous coronary intervention (PCI). We aimed to evaluate whether hyperglycemia predicts inhospital mortality. We prospectively analyzed 503 consecutive patients. The patients were divided into tertiles according to the admission glucose levels. Tertile I: glucose <118 mg/dL (n = 166), tertile II: glucose 118 to 145 mg/dL (n = 168), and tertile III: glucose >145 mg/dL (n = 169). Inhospital mortality was 0 in tertile I, 2 in tertile II, and 9 in tertile III (P < .02). Cardiogenic shock occurred more frequently in tertile III compared to tertiles I and II (10% vs 4.1% and 0.6%, respectively, P = .01). Multivariate logistic regression analysis revealed that patients in tertile III had significantly higher risk of inhospital major adverse cardiac events compared to patients in tertile I (odds ratio: 9.55, P < .02). Admission hyperglycemia predicts inhospital adverse cardiac events in mortality and acute ST-segment elevation myocardial infarction in patients that underwent primary PCI.
authors: 1Clinic of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital, Istanbul, Turkey.
authors: Ahmet
authors: A
authors: Ekmekci
authors: Gokhan
authors: G
authors: Cicek
authors: Mahmut
authors: M
authors: Uluganyan
authors: Baris
authors: B
authors: Gungor
authors: Faizel
authors: F
authors: Osman
authors: Kazim Serhan
authors: KS
authors: Ozcan
authors: Mehmet
authors: M
authors: Bozbay
authors: Gokhan
authors: G
authors: Ertas
authors: Aycan
authors: A
authors: Zencirci
authors: Nurten
authors: N
authors: Sayar
authors: Mehmet
authors: M
authors: Eren
mesh_terms: D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D006943:Hyperglycemia / Q000453:epidemiology*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy*; D010343:Patient Admission; D062645:Percutaneous Coronary Intervention
keywords: ST-segment elevation myocardial infarction; hyperglycemia; major adverse cardiac events; mortality