title: Osteoblastic cell response and bone formation of phosphate ion coated on plasma polymerized Ti surface.
abstract: This study examined the bone formation ability and cell response on a phosphate (PO3(4-)) ion exchanged amine plasma polymerized titanium (Ti) surface. The enhanced bone-like apatite (hydroxyapatite, HAp)-forming ability was attributed to the PO3(4-) ion exchanged amine plasma polymerized Ti (P/NH2/Ti) surface, which was formed by the reduction of PO3(4-) ions. PO3(4-) ions promote HAp nucleation and growth on Ti in SBF, and PO3(4-) ions improve the crystallinity of the HAp deposited layer. The cell viability tests revealed significantly greater cell viability on the P/NH2/Ti surfaces than on the other surfaces.
authors: Department of Ophthalmology, Chosun University College of Medicine, Gwangju, 501-759 Korea.
authors: Seong-Won
authors: SW
authors: Yang
authors: Kang
authors: K
authors: Lee
authors: Byung-Hoon
authors: BH
authors: Kim
mesh_terms: D000818:Animals; D041702:BALB 3T3 Cells; D002470:Cell Survival / Q000502:physiology; D020099:Coated Materials, Biocompatible / Q000138:chemical synthesis / Q000494:pharmacology; D003460:Crystallization / Q000379:methods; D046911:Macromolecular Substances / Q000737:chemistry; D008422:Materials Testing; D051379:Mice; D008968:Molecular Conformation; D049329:Nanostructures / Q000008:administration & dosage / Q000737:chemistry* / Q000648:ultrastructure; D010006:Osteoblasts / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D010012:Osteogenesis / Q000187:drug effects / Q000502:physiology*; D010316:Particle Size; D010710:Phosphates / Q000737:chemistry* / Q000494:pharmacology*; D011108:Polymers / Q000737:chemistry; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
chemical_list: D020099:Coated Materials, Biocompatible; D046911:Macromolecular Substances; D010710:Phosphates; D011108:Polymers; D014025:Titanium