title: Effect of pretreatment with calcium-containing desensitizer on the dentine bonding of mild self-etch adhesives.
abstract: Desensitizing agents are frequently applied to sensitive teeth and may affect subsequent resin bonding. The current study aimed to evaluate the bonding performance of two self-etch adhesives containing functional monomers to dentine pretreated with three new calcium-containing desensitizers. No desensitizer was applied in the control group. Groups 1, 2, and 3 were treated with an arginine-calcium carbonate-containing polishing paste, a casein phosphopeptide-amorphous calcium phosphate (CPP-ACP)-containing paste, and an experimental hydroxyapatite paste, respectively. G-Bond and Clearfil S(3) Bond were used for bonding after desensitizer treatments. The microtensile bond strength (μTBS) was tested (n = 20 beams per group) and failure mode distribution was analyzed. Scanning electron microscopy was used to observe the occlusion of dentinal tubules. The mean (±SD) μTBS values, expressed in MPa, of groups 1, 2, and 3 and the control group were, respectively, 30.81 (7.79), 44.41 (8.02), 31.49 (6.13), and 41.40 (8.67) for G-Bond and 39.63 (9.59), 32.55 (7.86), 37.50 (8.60), 27.90 (6.52) for S3 Bond. Most failures were recorded as adhesive failure (69.375%), instead of cohesive failure or mixed failure. The dentinal tubules were seldom plugged in group 2, but were mostly occluded in groups 1 and 3. Two-way anova indicated that desensitizer application in association with a compatible adhesive system should be used when endeavoring to control hypersensitivity without adverse interference in bonding.
authors: The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
authors: Dandan
authors: D
authors: Pei
authors: Siying
authors: S
authors: Liu
authors: Cui
authors: C
authors: Huang
authors: Xijin
authors: X
authors: Du
authors: Hongye
authors: H
authors: Yang
authors: Yake
authors: Y
authors: Wang
authors: Donglai
authors: D
authors: Deng
mesh_terms: D000704:Analysis of Variance; D001120:Arginine / Q000627:therapeutic use; D002118:Calcium; D002119:Calcium Carbonate / Q000627:therapeutic use; D002364:Caseins / Q000627:therapeutic use; D001840:Dental Bonding / Q000379:methods*; D003738:Dental Cements / Q000009:adverse effects*; D045662:Dental Etching; D057133:Dentin Desensitizing Agents / Q000737:chemistry / Q000627:therapeutic use*; D003807:Dentin Sensitivity / Q000209:etiology / Q000517:prevention & control*; D017220:Dentin-Bonding Agents / Q000009:adverse effects*; D006801:Humans; D006882:Hydroxyapatites / Q000627:therapeutic use; D008689:Methacrylates; D011292:Premedication; D019279:Resin Cements
chemical_list: D002364:Caseins; C505694:Clearfil S3 Bond; D003738:Dental Cements; D057133:Dentin Desensitizing Agents; D017220:Dentin-Bonding Agents; C498353:G-Bond; D006882:Hydroxyapatites; D008689:Methacrylates; D019279:Resin Cements; C447032:casein phosphopeptide-amorphous calcium phosphate nanocomplex; D001120:Arginine; D002119:Calcium Carbonate; D002118:Calcium