title: Examination of biologically active nanocomplexes by nanoparticle tracking analysis.
abstract: Nanoparticle tracking analysis (NTA) was first applied to biologically active nanocomplexes to obtain concurrent information on their size, state of aggregation, concentration, and antigenic specificity in liquid. The subject of the NTA was an immunogenic complex (a candidate nanovaccine) comprised of spherical particles (SPs) generated by thermal remodeling of the tobacco mosaic virus and Rubella virus tetraepitopes exposed on the surface of SP.
authors: Department of Virology, Moscow State University, Moscow 119991, Russia. nikitin@mail.bio.msu.ru
authors: Nikolai
authors: N
authors: Nikitin
authors: Ekaterina
authors: E
authors: Trifonova
authors: Olga
authors: O
authors: Karpova
authors: Joseph
authors: J
authors: Atabekov
mesh_terms: D000956:Antigens, Viral / Q000276:immunology; D001695:Biology / Q000379:methods*; D000939:Epitopes / Q000276:immunology; D053758:Nanoparticles / Q000032:analysis*; D012412:Rubella virus / Q000276:immunology; D014027:Tobacco Mosaic Virus / Q000276:immunology
chemical_list: D000956:Antigens, Viral; D000939:Epitopes