title: Transition metal-catalyzed functionalization of pyrazines.
abstract: Transition metal-catalyzed reactions are generally used for carbon-carbon bond formation on pyrazines and include, but are not limited to, classical palladium-catalyzed reactions like Sonogashira, Heck, Suzuki, and Stille reactions. Also a few examples of carbon-heteroatom bond formation in pyrazines are known. This perspective reviews recent progress in the field of transition metal-catalyzed cross-coupling reactions on pyrazine systems. It deals with the most important C-C- and C-X-bond formation methodologies.
authors: Laboratory of Molecular Nanofabrication, MESA+ Institute for Nanotechnology, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands.
authors: Nicolai I
authors: NI
authors: Nikishkin
authors: Jurriaan
authors: J
authors: Huskens
authors: Willem
authors: W
authors: Verboom