title: Long-term results after simple versus complex stenting of coronary artery bifurcation lesions: Nordic Bifurcation Study 5-year follow-up results.
abstract: OBJECTIVE
  This study sought to report the 5-year follow-up results of the Nordic Bifurcation Study.
  
  
  BACKGROUND
  Randomized clinical trials with short-term follow-up have indicated that coronary bifurcation lesions may be optimally treated using the optional side branch stenting strategy.
  
  
  METHODS
  A total of 413 patients with a coronary bifurcation lesion were randomly assigned to a simple stenting strategy of main vessel (MV) and optional stenting of side branch (SB) or to a complex stenting strategy, namely, stenting of both MV and SB.
  
  
  RESULTS
  Five-year clinical follow-up data were available for 404 (98%) patients. The combined safety and efficacy endpoint of cardiac death, non-procedure-related myocardial infarction, and target vessel revascularization were seen in 15.8% in the optional SB stenting group as compared to 21.8% in the MV and SB stenting group (p = 0.15). All-cause death was seen in 5.9% versus 10.4% (p = 0.16) and non-procedure-related myocardial infarction in 4% versus 7.9% (p = 0.09) in the optional SB stenting group versus the MV and SB stenting group, respectively. The rates of target vessel revascularization were 13.4% versus 18.3% (p = 0.14) and the rates of definite stent thrombosis were 3% versus 1.5% (p = 0.31) in the optional SB stenting group versus the MV and SB stenting group, respectively.
  
  
  CONCLUSIONS
  At 5-year follow-up in the Nordic Bifurcation Study, the clinical outcomes after simple optional side branch stenting remained at least equal to the more complex strategy of planned stenting of both the main vessel and the side branch.
authors: Department of Cardiology, Aarhus University Hospital, Skejby, Denmark. michael.maeng@ki.au.dk
authors: Michael
authors: M
authors: Maeng
authors: Niels R
authors: NR
authors: Holm
authors: Andrejs
authors: A
authors: Erglis
authors: Indulis
authors: I
authors: Kumsars
authors: Matti
authors: M
authors: Niemelä
authors: Kari
authors: K
authors: Kervinen
authors: Jan S
authors: JS
authors: Jensen
authors: Anders
authors: A
authors: Galløe
authors: Terje K
authors: TK
authors: Steigen
authors: Rune
authors: R
authors: Wiseth
authors: Inga
authors: I
authors: Narbute
authors: Pål
authors: P
authors: Gunnes
authors: Jan
authors: J
authors: Mannsverk
authors: Oliver
authors: O
authors: Meyerdierks
authors: Svein
authors: S
authors: Rotevatn
authors: Kjell
authors: K
authors: Nikus
authors: Saila
authors: S
authors: Vikman
authors: Jan
authors: J
authors: Ravkilde
authors: Stefan
authors: S
authors: James
authors: Jens
authors: J
authors: Aarøe
authors: Antti
authors: A
authors: Ylitalo
authors: Steffen
authors: S
authors: Helqvist
authors: Iwar
authors: I
authors: Sjögren
authors: Per
authors: P
authors: Thayssen
authors: Kari
authors: K
authors: Virtanen
authors: Mikko
authors: M
authors: Puhakka
authors: Juhani
authors: J
authors: Airaksinen
authors: Evald H
authors: EH
authors: Christiansen
authors: Jens F
authors: JF
authors: Lassen
authors: Leif
authors: L
authors: Thuesen
mesh_terms: D000368:Aged; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery*; D023903:Coronary Restenosis / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control; D003718:Denmark / Q000453:epidemiology; D054855:Drug-Eluting Stents; D005260:Female; D005387:Finland / Q000453:epidemiology; D005500:Follow-Up Studies; D006801:Humans; D007844:Latvia / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009664:Norway / Q000453:epidemiology; D062645:Percutaneous Coronary Intervention / Q000295:instrumentation / Q000379:methods / Q000639:trends*; D013548:Sweden / Q000453:epidemiology; D013997:Time Factors; D016896:Treatment Outcome