title: Functional neuroimaging of social and nonsocial cognitive control in autism.
abstract: This study investigated cognitive control of social and nonsocial information in autism using functional magnetic resonance imaging. Individuals with autism spectrum disorders (ASDs) and a neurotypical control group completed an oddball target detection task where target stimuli were either faces or nonsocial objects previously shown to be related to circumscribed interests in autism. The ASD group demonstrated relatively increased activation to social targets in right insular cortex and in left superior frontal gyrus and relatively decreased activation to nonsocial targets related to circumscribed interests in multiple frontostriatal brain regions. Findings suggest that frontostriatal recruitment during cognitive control in ASD is contingent on stimulus type, with increased activation for social stimuli and decreased activation for nonsocial stimuli related to circumscribed interests.
authors: Department of Psychology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, asabatin@email.unc.edu.
authors: Antoinette
authors: A
authors: Sabatino
authors: Alison
authors: A
authors: Rittenberg
authors: Noah J
authors: NJ
authors: Sasson
authors: Lauren
authors: L
authors: Turner-Brown
authors: James W
authors: JW
authors: Bodfish
authors: Gabriel S
authors: GS
authors: Dichter
mesh_terms: D000293:Adolescent; D000328:Adult; D001321:Autistic Disorder / Q000503:physiopathology / Q000523:psychology*; D001931:Brain Mapping / Q000379:methods*; D003071:Cognition; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D012919:Social Behavior; D055815:Young Adult
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