title: Acute necrotizing large vessel arteritis in a newborn: a case report and review of the literature.
abstract: Acute arteritis of the aorta and the main pulmonary arteries is unusual in a newborn. This type of vasculitis should be described as a separate entity. There are many differences between this entity and polyarteritis nodosa or Takayasu disease. Moreover, neither Takayasu disease nor polyarteritis nodosa and other forms of classic primary large vessels vasculitis have been reported in a neonate until now. The presence of chronic inflammation, fibrosis, and calcification would suggest that this process had been present before birth.We report a 27-day-old newborn with acute necrotizing aortitis. The feature of this entity is not those of any of the classic entities described in infants or children.
authors: Department of Pathology Laboratory, Fars Legal Medicine Research Center, PO Box 71345-1864, Shiraz, Iran.
authors: Arya
authors: A
authors: Hejazi
authors: Marzieh
authors: M
authors: Hosseini
authors: Mohammadreza
authors: M
authors: Bahrani
mesh_terms: D001011:Aorta / Q000473:pathology; D001025:Aortitis / Q000473:pathology*; D049429:Forensic Pathology; D006323:Heart Arrest / Q000209:etiology; D006470:Hemorrhage / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D009504:Neutrophils / Q000473:pathology; D010488:Polyarteritis Nodosa / Q000473:pathology*; D011651:Pulmonary Artery / Q000473:pathology; D012131:Respiratory Insufficiency / Q000209:etiology