title: Populations at risk for alveolar echinococcosis, France.
abstract: During 1982-2007, alveolar echinococcosis (AE) was diagnosed in 407 patients in France, a country previously known to register half of all European patients. To better define high-risk groups in France, we conducted a national registry-based study to identify areas where persons were at risk and spatial clusters of cases. We interviewed 180 AE patients about their way of life and compared responses to those of 517 controls. We found that almost all AE patients lived in 22 départements in eastern and central France (relative risk 78.63, 95% CI 52.84-117.02). Classification and regression tree analysis showed that the main risk factor was living in AE-endemic areas. There, most at-risk populations lived in rural settings (odds ratio [OR] 66.67, 95% CI 6.21-464.51 for farmers and OR 6.98, 95% CI 2.88-18.25 for other persons) or gardened in nonrural settings (OR 4.30, 95% CI 1.82-10.91). These findings can help sensitization campaigns focus on specific groups.
authors: Aix-Marseille University, Marseille, France.
authors: Martine
authors: M
authors: Piarroux
authors: Renaud
authors: R
authors: Piarroux
authors: Jenny
authors: J
authors: Knapp
authors: Karine
authors: K
authors: Bardonnet
authors: Jérôme
authors: J
authors: Dumortier
authors: Jérôme
authors: J
authors: Watelet
authors: Alain
authors: A
authors: Gerard
authors: Jean
authors: J
authors: Beytout
authors: Armand
authors: A
authors: Abergel
authors: Solange
authors: S
authors: Bresson-Hadni
authors: Jean
authors: J
authors: Gaudart
mesh_terms: D000328:Adult; D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D004443:Echinococcosis; D004444:Echinococcosis, Hepatic / Q000188:drug therapy / Q000453:epidemiology* / Q000469:parasitology / Q000635:transmission; D048210:Echinococcus multilocularis / Q000187:drug effects / Q000502:physiology*; D019353:Endemic Diseases; D005260:Female; D005589:Foxes / Q000469:parasitology; D005602:France / Q000453:epidemiology; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000469:parasitology; D008297:Male; D008463:Mebendazole / Q000627:therapeutic use; D008875:Middle Aged; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D012424:Rural Population; D012959:Socioeconomic Factors
chemical_list: D000871:Anthelmintics; D008463:Mebendazole; D015766:Albendazole
keywords: Echinococcus multilocularis; France; agricultural workers diseases; alveolar echinococcosis; communicable disease prevention and control; epidemiology; parasites; risk factors; rural health; zoonoses
references: Parasitology. 2003;127 Suppl:S121-31
references: 15027609
references: Parasitology. 2003;127 Suppl:S87-107
references: 15027607
references: Parasitology. 2003;127 Suppl:S133-41
references: 15027610
references: Parasite. 2008 Mar;15(1):77-85
references: 18416250
references: Emerg Infect Dis. 2004 Dec;10(12):2088-93
references: 15663843
references: Acta Trop. 2000 Nov 2;77(2):167-77
references: 11080507
references: Emerg Infect Dis. 2006 Nov;12(11):1689-95
references: 17283618
references: Trends Parasitol. 2004 Feb;20(2):77-84
references: 14747021
references: BMC Public Health. 2008 Jul 21;8:247
references: 18644138
references: Med Mal Infect. 2008 Jun;38 Suppl 2:S74-7
references: 18598877
references: Vet Res Commun. 2009 Sep;33 Suppl 1:31-4
references: 19578966
references: Emerg Infect Dis. 2004 May;10(5):858-64
references: 15200820
references: East Afr Med J. 2003 Aug;80(8):395-7
references: 14601778
references: J Hepatol. 2011 Nov;55(5):1025-33
references: 21354448
references: Emerg Infect Dis. 2010 Feb;16(2):231-7
references: 20113552
references: Int J Parasitol. 2001 Dec;31(14):1579-88
references: 11730784
references: Emerg Infect Dis. 2003 Mar;9(3):343-9
references: 12643830
references: Bull World Health Organ. 1996;74(3):231-42
references: 8789923
references: Emerg Infect Dis. 2012 Dec;18(12):2059-62
references: 23171707
references: PLoS Negl Trop Dis. 2009 Jun 09;3(6):e452
references: 19513103
references: Am J Trop Med Hyg. 1988 Mar;38(2):380-5
references: 3354771
references: Acta Trop. 2010 Apr;114(1):1-16
references: 19931502
references: Clin Microbiol Infect. 2010 Jun;16(6):788-91
references: 19912267
references: Am J Trop Med Hyg. 2006 May;74(5):856-62
references: 16687693
references: Int J Parasitol. 2009 Jun;39(7):837-42
references: 19150351
references: Curr Opin Infect Dis. 2010 Oct;23(5):505-12
references: 20683265
references: Am J Epidemiol. 1998 May 15;147(10):978-81
references: 9596476
references: Emerg Infect Dis. 2007 Jun;13(6):878-82
references: 17553227
references: Chin Med J (Engl). 2011 Sep;124(18):2943-53
references: 22040507
references: Community Health Stud. 1990;14(2):132-7
references: 2208977
references: Emerg Infect Dis. 2005 Dec;11(12):1866-73
references: 16485472
references: Am J Trop Med Hyg. 1999 Oct;61(4):559-65
references: 10548289
references: Parasitology. 2003;127 Suppl:S159-72
references: 15027612
references: Epidemiol Infect. 2012 May;140(5):867-71
references: 21733269