title: Mortality among patients who receive or defer gastrostomies.
abstract: OBJECTIVE
  There are few data on outcomes and mortality of patients who have received gastrostomies. We assessed 30-day and 1-year mortalities of patients in the United Kingdom who were referred to hospitals for gastrostomies and of patients who deferred this intervention.
  
  
  METHODS
  We collected data from 1327 patients referred to 2 hospitals in Sheffield, United Kingdom, for gastrostomies from February 2004 through May 2010. Data were analyzed to determine 30-day and 1-year mortalities. Predicted mortality by using the validated Sheffield Gastrostomy Scoring System (SGSS) was then compared with actual mortality by using area under the receiver operator curves to determine levels of agreement in patients referred for gastrostomy.
  
  
  RESULTS
  Three hundred four patients (23%) did not undergo gastrostomy after multidisciplinary team discussion, which was based on physicians' recommendations. This group had 35.5% mortality at 30 days and 74.3% at 1 year, whereas mortality among patients who underwent gastrostomy (n = 1027) was 11.2% at 30 days and 41.1% at 1 year (P < .0001, compared with patients who deferred the procedure). The area under the receiver operator curves for the SGSS demonstrated acceptable agreement between predicted and actual mortality in patients who underwent or were deferred gastrostomy.
  
  
  CONCLUSIONS
  On the basis of data from 1327 patients, those who undergo gastrostomy have significantly lower mortality than those who defer the procedure. Without applying the SGSS, clinicians are able to select patients most likely to benefit from gastrostomy. The SGSS could provide objective support to clinicians involved in making ethically contentious or potentially litigious decisions.
authors: Gastroenterology and Liver Unit, Royal Hallamshire Hospital, Sheffield Teaching Hospitals, Sheffield, United Kingdom. Electronic address: matthew.kurien@sth.nhs.uk.
authors: Matthew
authors: M
authors: Kurien
authors: John S
authors: JS
authors: Leeds
authors: Mark H
authors: MH
authors: Delegge
authors: Helen E
authors: HE
authors: Robson
authors: Julia
authors: J
authors: Grant
authors: Frederick K T
authors: FK
authors: Lee
authors: Mark E
authors: ME
authors: McAlindon
authors: David S
authors: DS
authors: Sanders
mesh_terms: D000368:Aged; D015331:Cohort Studies; D005260:Female; D005774:Gastrostomy / Q000379:methods*; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D013272:Stomach Diseases / Q000401:mortality* / Q000601:surgery*; D016019:Survival Analysis; D006113:United Kingdom
keywords: AUC; Deferred; Gastrostomy; Mortality; PEG; PIG; Prediction; SGSS; Scoring Systems; Sheffield Gastrostomy Scoring System; area under the receiver operator curves; per-oral image-guided gastrostomy; percutaneous endoscopic gastrostomy