title: 2-Amino-4-(4-chloro-phen-yl)-4H-chromeno[8,7-b]pyridine-3-carbonitrile.
abstract: The asymmetric unit of the title compound, C19H12ClN3O, contains two mol-ecules with similar conformations. The 14 non-H atoms comprising the 4H-chromeno[8,7-b]pyridine residue are essentially coplanar (r.m.s. deviations = 0.037 and 0.042 Å for the two mol-ecules) and the main difference between them is seen in the twist about the bond linking the main residue to the attached chloro-benzene rings [dihedral angles = 79.01 (12) and 76.22 (11)° for the two mol-ecules]. Zigzag supra-molecular chains along the a-axis direction mediated by amino-pyridine N-H⋯N hydrogen bonds feature in the crystal packing; these are connected into a three-dimensional architecture by C-H⋯π inter-actions and Cl⋯Cl contacts [Cl⋯Cl = 3.3896 (14) Å].
authors: Drug Exploration & Development Chair (DEDC), College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia ; Applied Organic Chemistry Department, National Research Center, Dokki 12622, Cairo, Egypt.
authors: Abd El-Galil E
authors: Ael-G
authors: Amr
authors: Ahmed M
authors: AM
authors: El-Agrody
authors: Nermien M
authors: NM
authors: Sabry
authors: Seik Weng
authors: SW
authors: Ng
authors: Edward R T
authors: ER
authors: Tiekink
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references: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
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