title: ABO blood group: old dogma, new perspectives.
abstract: Human blood group antigens are glycoproteins and glycolipids expressed on the surface of red blood cells and a variety of human tissues, including the epithelium, sensory neurons, platelets and the vascular endothelium. Accumulating evidence indicate that ABO blood type is implicated in the development of a number of human diseases, including cardiovascular and neoplastic disorders. In this review, beside its physiologic role in immunohematology and transfusion medicine, we summarize the current knowledge on the association between the ABO blood group and the risk of developing thrombotic events and cancers.
authors: Department of Transfusion Medicine and Hematology, Azienda Ospedaliera Carlo Poma, Mantova, Italy. massimo.franchini@aopoma.it
authors: Massimo
authors: M
authors: Franchini
authors: Giancarlo Maria
authors: GM
authors: Liumbruno
mesh_terms: D000017:ABO Blood-Group System / Q000032:analysis / Q000276:immunology; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000276:immunology*; D006801:Humans; D009369:Neoplasms / Q000453:epidemiology / Q000276:immunology*; D012307:Risk Factors
chemical_list: D000017:ABO Blood-Group System