title: Salak plum peel extract as a safe and efficient antioxidant appraisal for cosmetics.
abstract: The antioxidant activities of Salak plum (Salacca edulis) peel extracts were assessed by 1, 1-diphenyl-2-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothaiazoline)-6-sulfonic acid (ABTS), and ferric reducing ability of plasma (FRAP) assays. The ethyl acetate (EtOAc) fraction was the most potent (DPPHIC50=2.932 ± 0.030 µg/mL, ABTSIC50=7.933 ± 0.049 µg/mL, FRAPEC=7,844.44 ± 40.734). Chlorogenic acid was detected as the marker (1.400 ± 0.102 g/kg). The EtOAc fraction was non-cytotoxic in vero and normal human fibroblast (NHF) cells. It exhibited cellular oxidative prevention and damage treatment at 5-40 µg/mL in NHF cells. Salak plum peel loaded liposome consisting of lecithin and hydrophobically modified hydroxyethylcellulose (HMHEC) was developed and found stable with adequate entrapment efficacy. Thus Salak plum peel was highlighted as a potential ecological antioxidant for health promotion aspects, and for cosmetics.
authors: School of Cosmetic Science, Mae Fah Luang University, Chiang Rai, Thailand. mayuree@mfu.ac.th
authors: Mayuree
authors: M
authors: Kanlayavattanakul
authors: Nattaya
authors: N
authors: Lourith
authors: Dusadee
authors: D
authors: Ospondpant
authors: Uracha
authors: U
authors: Ruktanonchai
authors: Siriluck
authors: S
authors: Pongpunyayuen
authors: Chaisak
authors: C
authors: Chansriniyom
mesh_terms: D000085:Acetates / Q000737:chemistry; D000818:Animals; D000975:Antioxidants / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D028023:Arecaceae / Q000737:chemistry*; D002522:Chlorocebus aethiops; D003358:Cosmetics / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D004355:Drug Stability; D006801:Humans; D008081:Liposomes; D053758:Nanoparticles / Q000737:chemistry; D019441:Plant Epidermis / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D012015:Reference Standards; D012449:Safety; D014709:Vero Cells
chemical_list: D000085:Acetates; D000975:Antioxidants; D003358:Cosmetics; D008081:Liposomes; D010936:Plant Extracts; C007650:ethyl acetate