title: [Study on the rates of infection and spontaneous clearance on HCV among HIV-infected men who have sex with men in China].
abstract: OBJECTIVE
  The aim of this study was to understand the rates of infection and spontaneous clearance on hepatitis C virus (HCV) among HIV-infected men who have sex with men (MSM) in China.
  
  
  METHODS
  HIV-infected MSM from Shenyang, Beijing, Changsha and Kunming were selected to take the HCV antibody and HVC-RNA tests, and then classified into 'under recovery (RNA-/Ab+) ' or being chronic (RNA+/Ab+). Information on demography, CD4(+) T cell, HIV viral load and liver biochemical indicators were also collected.
  
  
  RESULTS
  In 513 HIV-infected MSM, the positive rate of HCV antibody was 1.94% (10/513) and the positive rate of HVC-RNA was 0.77% (4/513). Five patients showed clearance of HVC-RNA, spontaneously. These 5 patients had low levels of both alanine transaminase (ALT) and aspartate aminotransferase (AST), and with high level of CD4(+) T cells, when compared to those who were not able to clear the HVC-RNA.
  
  
  CONCLUSIONS
  Currently, the HCV infection rate was still at quite low level among the HIV-infected MSM in China. Dynamic of HIV/HCV co-infection should be monitored so as to develop suitable strategy on prevention and treatment among this population, in China.
authors: Department of Laboratory Medicine, the First Hospital of China Medical University, Shenyang, China.
authors: Ming-hui
authors: MH
authors: An
authors: Xiao-xu
authors: XX
authors: Han
authors: Jing
authors: J
authors: Liu
authors: Hao
authors: H
authors: Wu
authors: Xi
authors: X
authors: Chen
authors: Lin
authors: L
authors: Lu
authors: Jun-jie
authors: JJ
authors: Xu
authors: Min
authors: M
authors: Zhang
authors: Hong
authors: H
authors: Shang
mesh_terms: D000328:Adult; D002681:China / Q000453:epidemiology; D060085:Coinfection / Q000453:epidemiology* / Q000821:virology; D006679:HIV Seropositivity; D015497:HIV-1; D016174:Hepacivirus; D006526:Hepatitis C / Q000453:epidemiology* / Q000821:virology; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D012367:RNA, Viral / Q000097:blood; D012075:Remission, Spontaneous; D019562:Viral Load; D055815:Young Adult
chemical_list: D012367:RNA, Viral