title: 7-Hy-droxy-methyl-2-pivaloyl-amino-1,8-naphthyridine.
abstract: In the title compound, C14H17N3O2, the mean plane of the 1,8-naphthyridine ring system (r.m.s deviation = 0.020 Å) forms a dihedral angle of 23.4 (1)° with the acetamide moiety (r.m.s deviation = 0.001 Å). The mol-ecular structure is stabilized by an intra-molecular O-H⋯N hydrogen bond, which generates an S(5) ring motif. In the crystal, mol-ecules are linked into inversion dimers by pairs of N-H⋯O hydrogen bonds, generating 18-membered R 2 (2)(18) ring motifs.
authors: X-ray Crystallography Unit, School of Physics, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia ; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, PO Box 2457, Riyadh 11451, Saudi Arabia.
authors: Hoong-Kun
authors: HK
authors: Fun
authors: Ching Kheng
authors: CK
authors: Quah
authors: Krishnendu
authors: K
authors: Aich
authors: Sangita
authors: S
authors: Das
authors: Shyamaprosad
authors: S
authors: Goswami
references: Eur J Med Chem. 2001 Nov-Dec;36(11-12):925-34
references: 11755235
references: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references: 18156677
references: Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55
references: 19171970