title: Myxedema ascites with high CA-125: Case and a review of literature.
abstract: Ascites appearing in a previously healthy female patient is usually ascribed to a variety of causes, among which, is a cancerous process, especially if it comes with a raised CA-125 level. Although the CA-125 antigen is present on more than 80% of malignant epithelial ovarian tissue of non-mucinous type, it is also found on both healthy and malignant cells of mesothelial and non-mesothelial origin. Myxedema ascites which is caused by hypothyroidism is a rare entity, but on the other hand is easy to treat. It is one of the differential diagnoses when the ascites is refractory to treatment and no other obvious cause can be identified. If the diagnosis is delayed, patients will frequently receive unnecessary procedures, while treatment has very good response rates and ascites resolve with serum CA-125 normalization after adequate hormonal treatment.
authors: Roula Bou Khalil, Patrick El Rassi, Nizar Chammas, Jean Obeid, Maroun Ghabach, Charles Sakr, Tarek Itani, Said Farhat, Quarantaine Governmental University Medical Hospital, Beirut 961, Lebanon.
authors: Roula
authors: R
authors: Bou Khalil
authors: Patrick
authors: P
authors: El Rassi
authors: Nizar
authors: N
authors: Chammas
authors: Jean
authors: J
authors: Obeid
authors: Maroun
authors: M
authors: Ghabach
authors: Charles
authors: C
authors: Sakr
authors: Tarek
authors: T
authors: Itani
authors: Said
authors: S
authors: Farhat
keywords: Abdominal paracentesis; High CA-125; Hormonal therapy; Hypothyroidism; Refractory ascites
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