title: Amaurosis fugax in ocular vascular occlusive disorders: prevalence and pathogeneses.
abstract: OBJECTIVE
  To investigate systematically the prevalence of amaurosis fugax (AF) in various ocular vascular occlusive disorders individually and to discuss the pathogeneses of each.
  
  
  METHODS
  The study comprised patients with central retinal artery occlusion (271 eyes), branch retinal artery occlusion (169 eyes), ocular ischemic syndrome (39 eyes), central retinal vein occlusion (864 eyes), hemi-central retinal vein occlusion (67 eyes), branch retinal vein occlusion (285 eyes), nonarteritic anterior ischemic optic neuropathy (946 eyes), and giant cell arteritis with visual loss (147 eyes). At first visit, all patients had a detailed ophthalmic and medical history and comprehensive ophthalmic evaluation and systemic evaluation.
  
  
  RESULTS
  Prevalence of AF was 12.18% in central retinal artery occlusion, 14.20% in branch retinal artery occlusion, 15.38% in ocular ischemic syndrome, 4.86% in central retinal vein occlusion, 37.84% in central retinal vein occlusion with cilioretinal artery occlusion, 13.43% in hemi-central retinal vein occlusion, 0.35% in branch retinal vein occlusion, and 2.54% in nonarteritic anterior ischemic optic neuropathy. In giant cell arteritis, 32.4% of patients with ocular involvement had a history of AF or 26.5% of the involved eyes. Amaurosis fugax in central retinal artery occlusion, branch retinal artery occlusion, and nonarteritic anterior ischemic optic neuropathy is mostly because of transient embolism. The pathogenesis of AF in each ocular vascular occlusive disorder is discussed.
  
  
  CONCLUSIONS
  Prevalence and pathogenesis of AF in various ocular vascular occlusive disorders varies widely. Amaurosis fugax may be the presenting symptom in these disorders and that always requires urgent evaluation.
authors: *Department of Ophthalmology and Visual Sciences, College of Medicine, and †Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa.
authors: Sohan S
authors: SS
authors: Hayreh
authors: M Bridget
authors: MB
authors: Zimmerman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D020757:Amaurosis Fugax / Q000453:epidemiology* / Q000209:etiology*; D001794:Blood Pressure; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D018917:Optic Neuropathy, Ischemic / Q000150:complications* / Q000175:diagnosis; D015995:Prevalence; D011446:Prospective Studies; D015356:Retinal Artery Occlusion / Q000150:complications* / Q000175:diagnosis; D012170:Retinal Vein Occlusion / Q000150:complications* / Q000175:diagnosis; D055815:Young Adult