title: [History, changes, and perspectives of AF therapy and research].
abstract: By reviewing the history of therapy and research regarding to atrial fibrillation(AF), we will be able to understand the most important viewpoint over the current and future treatment of AF, which would provide an aid for future perspective into the clinical and basic research targeting AF. Around 2000's, a major turning point of a paradigm shift occurred from the changes in the age proportion of the society that altered the prevalence and prognosis of AF patients and also the changes in the needs from the society. A future perspective should be discussed from this turning point.
authors: The Department of Cardiovascular Medicine, The Cardiovascular Institute.
authors: Takeshi
authors: T
authors: Yamashita
mesh_terms: D000818:Animals; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000628:therapy*; D035843:Biomedical Research; D055808:Drug Discovery; D022062:Electrophysiologic Techniques, Cardiac; D006801:Humans; D011379:Prognosis; D020521:Stroke / Q000175:diagnosis / Q000628:therapy