title: Simulation of incomplete obstructive uropathy in rats by injecting an artificial calculus into the bladder.
abstract: Incomplete varying obstruction of the urinary tract was reproduced by injecting artificial stomatological material into the rat bladder. Inflammatory changes and nephrosclerosis were detected in the renal tissue on days 14 and 21 of the experiment. Urinary concentration of total protein and activity of γ-glutamylaminotransferase increased. A direct positive correlation between the volume percentage of connective tissue and activities of the renal enzymes in the urine was detected.
authors: Volgograd State Medical University, Russia. dasosnin@yandex.ru
authors: D A
authors: DA
authors: Sosnin
authors: V V
authors: VV
authors: Novochadov
authors: O V
authors: OV
authors: Ostrovsky
mesh_terms: D000464:Alginates; D000818:Animals; D004195:Disease Models, Animal; D020723:Glucuronic Acid; D006603:Hexuronic Acids; D007668:Kidney / Q000473:pathology*; D008297:Male; D011507:Proteinuria / Q000473:pathology* / Q000652:urine; D051381:Rats; D014524:Urethral Obstruction / Q000473:pathology* / Q000652:urine; D001743:Urinary Bladder / Q000473:pathology; D014545:Urinary Calculi / Q000473:pathology* / Q000652:urine; D005723:gamma-Glutamyltransferase / Q000652:urine
chemical_list: D000464:Alginates; D006603:Hexuronic Acids; D020723:Glucuronic Acid; D005723:gamma-Glutamyltransferase