title: Gender difference in antidepressant-related sexual dysfunction in Taiwan.
abstract: OBJECTIVE
  Sexual dysfunction accompanied by depression may be altered by antidepressants. The effects of antidepressants on sexual dysfunction among males and females remain to be investigated.
  
  
  METHODS
  Three groups of subjects, drug-free patients with depression (N=125), medicated patients with depression (N=145) and healthy volunteers (N=255), were recruited. A Chinese version of the Changes in Sexual Functioning Questionnaire was employed to assess sexual function as the primary outcome.
  
  
  RESULTS
  Drug-free depressed females and medicated depressed males had more sexual dysfunction than healthy controls. The desire for sexual behaviors among healthy females and medicated depressed females was higher than that of drug-free depressed females.
  
  
  CONCLUSIONS
  Depression and antidepressants may have different impacts on the sexual function of males and females.
authors: Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
authors: Tzu I
authors: TI
authors: Lee
authors: Joana
authors: J
authors: Issac
authors: Shih-Hsien
authors: SH
authors: Lin
authors: Tzung Lieh
authors: TL
authors: Yeh
authors: I Hui
authors: IH
authors: Lee
authors: Po See
authors: PS
authors: Chen
authors: Kao Chin
authors: KC
authors: Chen
authors: Yen Kuang
authors: YK
authors: Yang
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D016022:Case-Control Studies; D003866:Depressive Disorder / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017678:Sex Distribution; D012737:Sex Factors; D012735:Sexual Dysfunction, Physiological / Q000139:chemically induced* / Q000150:complications; D020018:Sexual Dysfunctions, Psychological / Q000150:complications*; D013624:Taiwan; D055815:Young Adult
chemical_list: D000928:Antidepressive Agents