title: [The application of mitochondrial genomics to forensic investigations based on human mitochondrial DNA testing].
abstract: In this study we present two forensic cases where mitochondrial DNA HVS I and HVS II haplotypes of evidentiary hairs match reference samples. Based on the information retrieved from mtDNA coding region of reference material, we selected single nucleotide polymorphisms (SNPs) located outside the HVS I and HVS II regions that could increase the informativeness of mtDNA analysis. The SNPs were typed via SNaPshot or dideoxy sequencing technology. In both cases the SNP results allowed for unambiguous exlusion of the evidence and for determining that reference samples originated from the same person.
authors: Zakładu Genetyki Molekularnej i Sadowej Katedry Medycyny Sadowej, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy Uniwersytetu Mikołaja Kopernika w Toruniu.
authors: Katarzyna
authors: K
authors: Skonieczna
authors: Jarosław
authors: J
authors: Bednarek
authors: Urszula
authors: U
authors: Rogalla
authors: Marcin
authors: M
authors: Woźniak
authors: Marta
authors: M
authors: Gorzkiewicz
authors: Katarzyna
authors: K
authors: Linkowska
authors: Anna
authors: A
authors: Duleba
authors: Karol
authors: K
authors: Sliwka
authors: Tomasz
authors: T
authors: Grzybowski
mesh_terms: D016172:DNA Fingerprinting / Q000379:methods*; D004252:DNA Mutational Analysis / Q000379:methods; D004272:DNA, Mitochondrial / Q000235:genetics*; D005260:Female; D053803:Forensic Genetics / Q000379:methods*; D006197:Hair / Q000737:chemistry*; D006708:Homicide; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D016415:Sequence Alignment
chemical_list: D004272:DNA, Mitochondrial