title: Assessment of glomerular filtration rate measurement with plasma sampling: a technical review.
abstract: This article reviews available radionuclide-based techniques for glomerular filtration rate (GFR) measurement, focusing on clinical indications for GFR measurement, ideal GFR radiopharmaceutical tracer properties, and the 2 most common tracers in clinical use. Methods for full, 1-compartment, and single-sample renal clearance characterization are discussed. GFR normalization and the role of GFR measurement in chemotherapy dosing are also considered.
authors: Department of Medical Physics, St. James's University Hospital, Leeds, United Kingdom. awm@medphysics.leeds.ac.uk
authors: Anthony W
authors: AW
authors: Murray
authors: Mark C
authors: MC
authors: Barnfield
authors: Michael L
authors: ML
authors: Waller
authors: Tania
authors: T
authors: Telford
authors: A Michael
authors: AM
authors: Peters
mesh_terms: D000970:Antineoplastic Agents / Q000097:blood / Q000493:pharmacokinetics / Q000494:pharmacology; D001774:Blood Chemical Analysis / Q000379:methods*; D005919:Glomerular Filtration Rate; D006801:Humans; D007677:Kidney Function Tests / Q000379:methods*; D011849:Radioactive Tracers
chemical_list: D000970:Antineoplastic Agents; D011849:Radioactive Tracers
keywords: GFR measurement; GFR normalization; glomerular filtration rate; radiopharmaceutical tracer; technical review