title: Autologous fat grafting for treatment of facial atrophy in Behcet's disease: a case report.
abstract: Behcet's disease (BD) is an autoimmune & autoinflammatory disease of unclear etiology characterized by recurrent oral & genital ulcers as well as other systemic manifestations. A key pathogenesis is excessive inflammatory wound healing response. While descriptions of the cutaneous manifestations of disease are limited to short-term consequences such as extensive pustule and papule formation in response to minor tissue injury, the long-term consequences are significant fibrosis and scarring of epithelial tissue. We describe the case of a patient with Behcet's disease who presented with unilateral facial atrophy secondary to minor trauma to the oral mucosa. She was treated with autologous fat grafting. Though a rare disease, plastic surgeons should be aware of the entity of Behcet's disease and its complications of tissue atrophy that may require reconstructive surgery.
authors: NYU Langone Medical Center, Institute of Reconstructive Plastic Surgery, USA.
authors: Z-Hye
authors: ZH
authors: Lee
authors: Kamran
authors: K
authors: Khoobehi
authors: Ernest S
authors: ES
authors: Chiu
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D001284:Atrophy; D064592:Autografts; D001528:Behcet Syndrome / Q000150:complications / Q000473:pathology* / Q000601:surgery*; D002610:Cheek / Q000473:pathology*; D002921:Cicatrix / Q000601:surgery; D005146:Facial Asymmetry / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous; D008875:Middle Aged; D019226:Oral Ulcer / Q000473:pathology; D019651:Plastic Surgery Procedures
keywords: Autologous fat grafting; Behcet's disease; Facial atrophy; Reconstructive surgery