title: Deprotection of the methoxymethyl group on 3-spiro-2-oxindole under basic conditions.
abstract: Deprotection of a methoxymethyl (MOM) group on an oxindole nitrogen under basic conditions is demonstrated. The mechanisms of both the deprotection and the formation of N-methyloxindole were revealed by using deuterated NaOMe-MeOH in mechanistic studies.
authors: Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan. nakazaki@agr.nagoya-u.ac.jp
authors: Atsuo
authors: A
authors: Nakazaki
authors: Kanako
authors: K
authors: Iwakiri
authors: Tomohiro
authors: T
authors: Hirano
authors: Takahiro
authors: T
authors: Suzuki
authors: Susumu
authors: S
authors: Kobayashi
mesh_terms: D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry; D008968:Molecular Conformation; D013141:Spiro Compounds / Q000737:chemistry*
chemical_list: D007211:Indoles; D013141:Spiro Compounds