title: Evaluation of autonomic nervous system by salivary alpha-amylase level and heart rate variability in patients with schizophrenia.
abstract: Several researches indicate that autonomic nervous system (ANS) dysfunction in patients with schizophrenia. Recently, salivary alpha-amylase (sAA) has been employed as a useful marker for ANS function. We investigated the extent of ANS dysfunction by measuring sAA and heart rate variability (HRV) of 25 patients with schizophrenia compared with controls. Schizophrenia group demonstrated a significant increase in sAA and markedly lower parasympathetic nervous system (PNS) activity in the HRV. However, there were no significant differences between two groups in sympathetic nervous system (SNS) activity. We concluded that PNS might be suppressed and the SNS shows relatively high activity in schizophrenia.
authors: Department of Psychiatry, Faculty of Medicine, Shimane University, 89-1 Enya-cho, Izumo, Shimane, 693-8501, Japan.
authors: Masa
authors: M
authors: Ieda
authors: Tsuyoshi
authors: T
authors: Miyaoka
authors: Rei
authors: R
authors: Wake
authors: Kristian
authors: K
authors: Liaury
authors: Keiko
authors: K
authors: Tsuchie
authors: Michiyo
authors: M
authors: Fukushima
authors: Tomoko
authors: T
authors: Araki
authors: Satoko
authors: S
authors: Ezoe
authors: Takuji
authors: T
authors: Inagaki
authors: Jun
authors: J
authors: Horiguchi
mesh_terms: D000328:Adult; D001342:Autonomic Nervous System Diseases / Q000175:diagnosis* / Q000209:etiology*; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D055291:Salivary alpha-Amylases / Q000378:metabolism*; D012559:Schizophrenia / Q000150:complications*; D013223:Statistics as Topic
chemical_list: D055291:Salivary alpha-Amylases
references: Int J Psychophysiol. 2000 Apr;36(1):59-68
references: 10700623
references: Psychoneuroendocrinology. 2007 May;32(4):392-401
references: 17418498
references: Psychiatry Clin Neurosci. 2009 Aug;63(4):538-45
references: 19496998
references: JAMA. 2000 Jan 26;283(4):506-11
references: 10659877
references: Ann N Y Acad Sci. 2004 Dec;1032:258-63
references: 15677423
references: Conf Proc IEEE Eng Med Biol Soc. 2005;2005:3538-41
references: 17280988
references: Clin Sci (Lond). 1998 Jun;94(6):579-84
references: 9854454
references: J Electromyogr Kinesiol. 2005 Jun;15(3):240-55
references: 15763671
references: Int J Psychophysiol. 1999 Jan;31(2):147-54
references: 9987060
references: Psychoneuroendocrinology. 2006 Jan;31(1):49-58
references: 16002223
references: Biol Psychol. 2012 Dec;91(3):342-8
references: 22954623
references: Psychoneuroendocrinology. 2006 Sep;31(8):976-87
references: 16879926
references: Int J Obes Relat Metab Disord. 1999 Aug;23(8):793-800
references: 10490779
references: Anesth Analg. 2005 Dec;101(6):1873-1876
references: 16301277
references: Science. 1981 Jul 10;213(4504):220-2
references: 6166045
references: Clin Biochem. 2008 Mar;41(4-5):325-30
references: 18062924
references: Biol Psychiatry. 1994 Jun 1;35(11):888-92
references: 8054413
references: Am Heart J. 2005 Dec;150(6):1115-21
references: 16338246
references: Biosens Bioelectron. 2006 Jan 15;21(7):1007-14
references: 15871919
references: J Psychiatr Res. 2005 Sep;39(5):519-27
references: 15992561
references: Prog Neuropsychopharmacol Biol Psychiatry. 2010 May 30;34(4):688-91
references: 20347911
references: Br J Psychiatry. 1998 Apr;172:331-6
references: 9715336
references: J Clin Psychopharmacol. 2003 Oct;23(5):441-7
references: 14520119
references: Ann Intern Med. 1993 Mar 15;118(6):436-47
references: 8439119
references: Psychoneuroendocrinology. 2006 Jan;31(1):137-41
references: 16046076
references: Psychiatry Res. 2008 Jan 15;157(1-3):255-7
references: 17919737
references: Neuropsychobiology. 2005;51(1):10-5
references: 15627808
references: Clin Neurophysiol. 2008 Oct;119(10):2209-13
references: 18722810
references: J Korean Acad Nurs. 2011 Dec;41(6):788-94
references: 22310863
references: Psychoneuroendocrinology. 2009 May;34(4):486-96
references: 19249160
references: Arch Oral Biol. 2004 Dec;49(12):963-8
references: 15485637
references: Biosens Bioelectron. 2004 Oct 15;20(3):491-7
references: 15494230
references: Circ Res. 1986 Aug;59(2):178-93
references: 2874900
references: Reg Anesth Pain Med. 2007 Mar-Apr;32(2):120-3
references: 17350522
references: J Psychopharmacol. 2009 Aug;23(6):697-707
references: 18562420
references: Int J Psychophysiol. 2005 Mar;55(3):333-42
references: 15708646