title: Struma ovarii maligna.
abstract: BACKGROUND
  Malignant struma ovarii is a rare ovarian neoplasm composed predominantly of mature thyroid tissue.
  
  
  METHODS
  A right ovarian tumor was discovered at ultrasound examination in a 20-year-old woman. Complete right ovariectomy was done - histopathological examination revealed papillary thyroid carcinoma arising in struma ovarii (malignant struma ovarii). Patient underwent subsequent total thyroidectomy - the thyroid was found to be without any pathological lesions. After operations the patient received ablative radioiodine treatment (200 mCi 131I). An 131I posttherapeutic whole-body radioiodine scintigraphy was performed and showed uptake in bone metastases. L-thyroxine TSH suppresive doses followed radioiodine ablation and thyroglobulin level is monitored. Next doses of radioiodine has been scheduled.
  
  
  CONCLUSIONS
  Authors suggest that the management of malignant struma ovarii should be the same as differentiated thyroid cancer, so after surgical excision of ovarian neoplasm, we recommend thyroidectomy, radiotherapy with 131I and levothyroxine suppressive therapy. Long-term follow-up for the detection of metastases or tumor recurrence by serial serum thyroglobulin measurements and 131I scan may be required in patients with this rare tumor.
authors: Department of Endocrinology, Metabolism and Internal Diseases, University of Medical Sciences, Poznan, Poland. matysiak-grzes@o2.pl
authors: Magdalena
authors: M
authors: Matysiak-Grzes
authors: Jakub
authors: J
authors: Fischbach
authors: Paweł
authors: P
authors: Gut
authors: Aleksandra
authors: A
authors: Klimowicz
authors: Maria
authors: M
authors: Gryczynska
authors: Ryszard
authors: R
authors: Wasko
authors: Marek
authors: M
authors: Ruchala
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D010051:Ovarian Neoplasms / Q000601:surgery*; D010052:Ovariectomy / Q000379:methods; D013330:Struma Ovarii / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D013964:Thyroid Neoplasms / Q000473:pathology / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods; D055815:Young Adult
chemical_list: D007457:Iodine Radioisotopes