title: Metabolic and hormonal consequences of two different meals after a moderate intensity exercise bout in obese prepubertal children.
abstract: OBJECTIVE
  To investigate the relationship between postprandial nutrient balance, satiety and hormone changes induced by two different meals taken after a moderate intensity exercise bout.
  
  
  METHODS
  Ten prepubertal obese children participated in the study. The experiment was designed as a cross-over study for repeated measures. Each test period lasted five consecutive hours during which the children were under medical supervision. The effects of two isocaloric meals were compared after a moderate intensity exercise (4 multiples of resting metabolic rate, 30 min, cycling): a low-fat/high-carbohydrate meal (meal A) and a high-fat/low-carbohydrate meal (meal B). Pre and postprandial (3 h) substrate oxidation, biochemical parameters, gastrointestinal hormone concentrations and appetite were measured.
  
  
  RESULTS
  The main results were: (i) higher fat balance (5.1±5.0 vs -5.0±6.6 g, P=0.001) and lower carbohydrate balance after meal B than A (-9.7±13.3 vs 11.3±18.3 g, P<0.01); (ii) higher energy balance after meal B than after meal A (5.9±21.5 vs -13.9±20.2 kcal, P<0.05); (iii) higher plasma triglyceride concentrations (area under the curve) after meal B than after meal A (2962.5±2095.8 mg*180 min/dl vs -169.5±1633.7 mg*180 min/dl, P<0.01); (iv) higher serum glucagon-like peptide-1 concentrations after meal B than after meal A (1101.5±873.0 pmol*180 min/l vs 478.8±638.3 pmol*180 min/l, P<0.05).
  
  
  CONCLUSIONS
  After a bout of moderate intensity exercise, a meal with a high-fat/low-carbohydrate ratio had a less favorable metabolic impact than an isoenergetic, isoproteic low-fat/high-carbohydrate meal.
authors: Department of Life and Reproduction Sciences, University of Verona, Verona, Italy. claudio.maffeis@univr.it
authors: C
authors: C
authors: Maffeis
authors: R
authors: R
authors: Bonadonna
authors: M
authors: M
authors: Maschio
authors: G
authors: G
authors: Aiello
authors: M
authors: M
authors: Tommasi
authors: M
authors: M
authors: Marigliano
authors: E
authors: E
authors: Fornari
authors: A
authors: A
authors: Morandi
mesh_terms: D001066:Appetite; D001481:Basal Metabolism; D001786:Blood Glucose / Q000032:analysis; D002648:Child; D018592:Cross-Over Studies; D050528:Diet, Carbohydrate-Restricted; D018752:Diet, Fat-Restricted; D059305:Diet, High-Fat; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D002149:Energy Intake; D015444:Exercise; D052216:Glucagon-Like Peptide 1 / Q000097:blood; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D062407:Meals; D063766:Pediatric Obesity / Q000378:metabolism*; D019518:Postprandial Period; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D007328:Insulin; D014280:Triglycerides; D052216:Glucagon-Like Peptide 1