title: Observation of mesenteric microcirculatory disturbance in rat by laser oblique scanning optical microscopy.
abstract: Ischemia-reperfusion (I/R) injury model has been widely applied to the study of microcirculation disturbance. In this work, we used laser oblique scanning optical microscopy (LOSOM) to observe the microcirculation system in the mesentery of rat model. Utilizing a localized point-scanning detection scheme, high-contrast images of leukocytes were obtained. The extended detection capability facilitated both the automatic in vivo cell counting and the accurate measurement of the rolling velocity of leukocytes. Statistical analysis of the different treatment groups suggested that the distinction between I/R and sham groups with time lapse is significant.
authors: Department of Biomedical Engineering, College of Engineering, Peking University, No. 5 Yiheyuan Road, Beijing 100871, China.
authors: Yichen
authors: Y
authors: Ding
authors: Yu
authors: Y
authors: Zhang
authors: Tong
authors: T
authors: Peng
authors: Yiqing
authors: Y
authors: Lu
authors: Dayong
authors: D
authors: Jin
authors: Qiushi
authors: Q
authors: Ren
authors: Yuying
authors: Y
authors: Liu
authors: Jingyan
authors: J
authors: Han
authors: Peng
authors: P
authors: Xi
mesh_terms: D000818:Animals; D007962:Leukocytes / Q000502:physiology; D008297:Male; D008643:Mesentery / Q000098:blood supply* / Q000502:physiology*; D008833:Microcirculation / Q000502:physiology; D018613:Microscopy, Confocal / Q000379:methods*; D051381:Rats; D017208:Rats, Wistar; D015427:Reperfusion Injury / Q000097:blood / Q000503:physiopathology
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