title: Pituitary granulomatosis with polyangiitis.
abstract: Granulomatosis with polyangiitis (GPA) is a small vessel vasculitis that can affect several organs, most commonly the respiratory tract and kidneys. Pituitary involvement is exceptionally rare. Most case reports of GPA of the pituitary gland have been described in middle-aged women who have concomitant ears, nose and throat involvement. The most frequent manifestation is diabetes insipidus due to a preponderance of posterior pituitary infiltration. The majority of cases sustain permanent damage to the pituitary gland even with remission of the underlying granulomatous disease. Here, the authors describe a case of pituitary GPA involving both the anterior and posterior pituitary glands with permanent residual pituitary insufficiency.
authors: Division of Endocrinology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
authors: Hannah
authors: H
authors: Slabu
authors: Terra
authors: T
authors: Arnason
mesh_terms: D000328:Adult; D005260:Female; D006099:Granuloma; D014890:Granulomatosis with Polyangiitis / Q000150:complications*; D006801:Humans; D007018:Hypopituitarism / Q000209:etiology*; D010902:Pituitary Gland / Q000473:pathology*; D010903:Pituitary Gland, Anterior / Q000473:pathology*; D010904:Pituitary Gland, Posterior / Q000473:pathology*
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