title: Retinol-binding protein 4 is elevated and is associated with free testosterone and TSH in postmenopausal women.
abstract: The aim of this study was to understand the relationship of retinol-binding protein 4 (RBP4) with hormonal and biochemical parameters in pre- and postmenopausal women. We included 69 postmenopausal women and 27 regularly menstruating premenopausal women. Postmenopausal women had statistically significantly higher RBP4 levels when compared to premenopausal women. RBP4 levels were negatively associated with free testosterone and positively associated with thyroid stimulating hormone in postmenopausal women. In premenopausal women RBP4 was positively associated with body mass index. RBP4 levels were increased in postmenopausal women. Although the mechanism is not clear, these findings suggest that RBP4 has a role in the regulation of hormonal and metabolic parameters.
authors: Department of Obstetrics and Gynecology, Istanbul Bilim University, Avrupa Hospıtal, Istanbul, Turkey. nilgun.kutay@gmail.com.
authors: N
authors: N
authors: Güdücü
authors: U
authors: U
authors: Görmüş
authors: Z N
authors: ZN
authors: Kavak
authors: H
authors: H
authors: İşçi
authors: A B
authors: AB
authors: Yiğiter
authors: İ
authors: İ
authors: Dünder
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood*; D001786:Blood Glucose / Q000032:analysis; D001823:Body Composition; D015992:Body Mass Index; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D017698:Postmenopause / Q000097:blood*; D017697:Premenopause / Q000097:blood*; D011379:Prognosis; D011446:Prospective Studies; D054839:Retinol-Binding Proteins, Plasma / Q000378:metabolism*; D013739:Testosterone / Q000097:blood*
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; C101326:RBP4 protein, human; D054839:Retinol-Binding Proteins, Plasma; D013739:Testosterone
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