title: [Smoking and aortic diseases].
abstract: Smoking is a major cause of cardiovascular risk factor. It is an independent risk factor for the onset and development of atherosclerotic vascular disease. Inflammation--and/or oxidative stress-induced vascular wall damage, particularly endothelial dysfunction, can be influenced by smoking. Endothelial dysfunction is an initiating event in atherogenesis, as well as a major factor in causing acute cardiovascular events. This review focuses on the mechanisms by which smoking causes aortic wall damage and subsequently induces clinical manifestation. Smoking cessation plays an important role in the management of atherosclerotic vascular disease.
authors: Department of Cardiology, Fukuoka University School of Medicine.
authors: Shinichiro
authors: S
authors: Miura
authors: Keijiro
authors: K
authors: Saku
mesh_terms: D001018:Aortic Diseases / Q000453:epidemiology / Q000209:etiology*; D004730:Endothelium, Vascular / Q000378:metabolism / Q000503:physiopathology; D006801:Humans; D007249:Inflammation / Q000209:etiology; D018384:Oxidative Stress / Q000187:drug effects; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*