title: Live mammalian cell arrays.
abstract: High-content assays have the potential to drastically increase throughput in cell biology and drug discovery, but handling and culturing large libraries of cells such as primary tumor or cancer cell lines requires expensive, dedicated robotic equipment. We developed a simple yet powerful method that uses contact spotting to generate high-density nanowell arrays of live mammalian cells for the culture and interrogation of cell libraries.
authors: Institute of Bioengineering, School of Engineering and School of Life Science, École Polytechnique Fédérale de Lausanne, Switzerland.
authors: Kristina
authors: K
authors: Woodruff
authors: Luis M
authors: LM
authors: Fidalgo
authors: Samy
authors: S
authors: Gobaa
authors: Matthias P
authors: MP
authors: Lutolf
authors: Sebastian J
authors: SJ
authors: Maerkl
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D002460:Cell Line; D002470:Cell Survival; D057166:High-Throughput Screening Assays / Q000379:methods*; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology; D051379:Mice; D041681:NIH 3T3 Cells; D046888:Tissue Array Analysis / Q000379:methods*
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