title: Effect of low fluoride acidic dentifrices on dental remineralization.
abstract: This study evaluated the capacity of fluoride acidic dentifrices (pH 4.5) to promote enamel remineralization using a pH cycling model, comparing them with a standard dentifrice (1,100 µgF/g). Enamel blocks had their surface polished and surface hardness determined (SH). Next, they were submitted to subsurface enamel demineralization and to post-demineralization surface hardness analysis. The blocks were divided into 6 experimental groups (n=10): placebo (without F, pH 4.5, negative control), 275, 412, 550, 1,100 µgF/g and a standard dentifrice (positive control). The blocks were submitted to pH cycling for 6 days and treatment with dentifrice slurries twice a day. After pH cycling, surface and cross-sectional hardness were assessed to obtain the percentage of surface hardness recovery (%SHR) and the integrated loss of subsurface hardness (ΔKHN). The results showed that %SHR was similar among acidic dentifrices with 412, 550, 1,100 µgF/g and to the positive control (Tukey's test; p>0.05). For ΔKHN, the acidic dentifrice with 550 µg F/g showed a better performance when compared with the positive control. It can be concluded that acidic dentifrice 550 µgF/g had similar remineralization capacity to that of positive control.
authors: Department of Pediatric Dentistry, Araçatuba Dental School, Univ Estadual Paulista, Araçatuba, SP, Brazil.
authors: Fernanda Lourenção
authors: FL
authors: Brighenti
authors: Eliana Mitsue
authors: EM
authors: Takeshita
authors: Camila de Oliveira
authors: Cde O
authors: Sant'ana
authors: Marília Afonso Rabelo
authors: MA
authors: Buzalaf
authors: Alberto Carlos Botazzo
authors: AC
authors: Delbem
mesh_terms: D000818:Animals; D002417:Cattle; D003743:Dental Enamel / Q000737:chemistry / Q000187:drug effects*; D003799:Dental Stress Analysis; D003802:Dentifrices / Q000737:chemistry / Q000494:pharmacology*; D005459:Fluorides / Q000032:analysis; D006244:Hardness / Q000187:drug effects; D006863:Hydrogen-Ion Concentration; D010758:Phosphorus / Q000032:analysis; D018709:Statistics, Nonparametric; D013499:Surface Properties; D014089:Tooth Remineralization
chemical_list: D003802:Dentifrices; D010758:Phosphorus; D005459:Fluorides