title: Executive functioning in chronic alcoholism and Korsakoff syndrome.
abstract: Korsakoff syndrome (KS) is characterized by dense anterograde and retrograde amnesia. There is often a temporal gradient to the retrograde amnesia, with earlier memories more readily recalled than recent memories. Executive functioning has also been found to be impaired in KS. However, research comparing executive functioning between chronic alcoholics (AL) and patients with KS has been relatively sparse to date. In a group comparison design, executive functioning in 15 KS patients and 16 chronic alcoholic patients was assessed using the Behavioural Assessment of the Dysexecutive Syndrome test (BADS) and other secondary measures. The KS group was found to be significantly more impaired than the AL group on overall performance on the BADS (p < .05). Korsakoff patients are significantly more impaired in executive functioning than non-Korsakoff chronic alcoholics. We thank the participants of the study and also acknowledge the support of the University of Nottingham, particularly Nadina Lincoln, and the North East London NHS Foundation Trust. We are also very grateful to the anonymous reviewers of earlier drafts of this manuscript for their invaluable comments.
authors: North East London NHS Foundation Trust, London, UK.
authors: Malini
authors: M
authors: Maharasingam
authors: Jamie A B
authors: JA
authors: Macniven
authors: Oliver J
authors: OJ
authors: Mason
mesh_terms: D000425:Alcohol Amnestic Disorder / Q000523:psychology*; D000437:Alcoholism / Q000523:psychology*; D001288:Attention / Q000502:physiology; D003627:Data Interpretation, Statistical; D004522:Educational Status; D056344:Executive Function / Q000187:drug effects* / Q000502:physiology*; D005260:Female; D005556:Form Perception / Q000502:physiology; D006801:Humans; D007361:Intelligence Tests; D007802:Language; D008297:Male; D008568:Memory / Q000502:physiology; D008569:Memory Disorders / Q000453:epidemiology / Q000523:psychology; D008875:Middle Aged; D009483:Neuropsychological Tests; D011597:Psychomotor Performance / Q000502:physiology; D011932:Reading; D013028:Space Perception / Q000502:physiology; D014888:Wechsler Scales