title: Comparative evaluation of subgingival plaque microflora in pregnant and non-pregnant women: A clinical and microbiologic study.
abstract: BACKGROUND
  Gingival changes in pregnancy have been attributed to changes in the subgingival biofilm related to hormonal variations.
  
  
  OBJECTIVE
  To evaluate the subgingival plaque microflora in pregnant and nonpregnant women to determine if pregnancy induces any alterations in the subgingival plaque and to associate these changes with changes in periodontal status.
  
  
  METHODS
  Thirty pregnant and 10 nonpregnant women within the age group of 20-35 years having a probing pocket depth (PPD) of 3-4 mm were included in the study. The pregnant women were equally divided into 3 groups of 10, each belonging to I, II, and III trimester.
  
  
  METHODS
  Plaque index, gingival index, PPD, and microbiologic evaluation for specific bacterial counts for Prevotella intermedia, Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Parvimonas micra, and Fusobacterium nucleatum were carried out for all subjects.
  
  
  METHODS
  Mann-Whitney U test.
  
  
  RESULTS
  Increase in gingival inflammation was observed in II and III trimester as compared with I trimester and control. Plaque scores did not show any significant difference between pregnant and nonpregnant women. Specific bacterial examination revealed an increase in proportion of P. intermedia in pregnant women of both II and III trimester as compared with I trimester and nonpregnant women.
  
  
  CONCLUSIONS
  A definite increase in proportions of P. intermedia occurs in subgingival plaque microflora in pregnancy that may be responsible for the exaggerated gingival response.
authors: Department of Periodontics, Royal Dental College, Kerala, India.
authors: Rishi
authors: R
authors: Emmatty
authors: Jayan Jacob
authors: JJ
authors: Mathew
authors: Jacob
authors: J
authors: Kuruvilla
keywords: Gingivitis; Prevotella intermedia; plaque; pregnancy
references: J Clin Periodontol. 1994 Sep;21(8):549-58
references: 7989619
references: J Periodontol. 1981 Oct;52(10):599-602
references: 6946202
references: J Dent. 1974 Feb;2(3):106-10
references: 4531436
references: Acta Odontol Scand. 1963 Dec;21:533-51
references: 14121956
references: J Dent Res. 1988 Aug;67(8):1062-9
references: 3261302
references: Odontol Revy. 1971;22(1):65-84
references: 5280517
references: Acta Odontol Scand. 1964 Feb;22:121-35
references: 14158464
references: J Periodontal Res. 1980 Mar;15(2):111-22
references: 6103927
references: J Periodontol. 1977 Sep;48(9):497-504
references: 333085
references: J Clin Periodontol. 1989 Apr;16(4):201-8
references: 2654195
references: Infect Immun. 1982 Jan;35(1):256-63
references: 6119293
references: J Clin Periodontol. 2010 Mar;37(3):230-40
references: 20088983
references: J Periodontol. 1965 May-Jun;36:209-17
references: 14300227