title: Influence of vanadium-organic ligands treatment on selected metal levels in kidneys of STZ rats.
abstract: The objective of the study was to investigate the effects of five organic vanadium complexes supplement and a small dose of insulin injection on V, Fe, Cu, Zn, Mn, Ca, and K level in the streptozotocin diabetic rat's kidney during a 5-week treatment with the tested complexes. In all groups of animals, metal level in the lyophilized kidney organs was investigated by means of the proton induced X-ray emission method. Tissue vanadium level was naturally higher in vanadium-treated rats. The maximum level of vanadium was observed in the kidney (x(mean) = 16.6 μg/g). The influence of vanadium administration on other metal level in rat's tissue was also investigated. Spectacular influence of vanadium action was observed on copper and zinc level in examined tissue.
authors: Department of Food Chemistry and Nutrition, Jagiellonian University Medical College, 30-688 Kraków, Poland. mfkrosni@cyf-kr.edu.pl
authors: Mirosław
authors: M
authors: Krośniak
authors: Joanna
authors: J
authors: Kowalska
authors: Renata
authors: R
authors: Francik
authors: Ryszard
authors: R
authors: Gryboś
authors: Magdalena
authors: M
authors: Blusz
authors: Wojciech M
authors: WM
authors: Kwiatek
mesh_terms: D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy / Q000378:metabolism; D007668:Kidney / Q000378:metabolism*; D008024:Ligands; D008297:Male; D008670:Metals / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D013311:Streptozocin; D014639:Vanadium / Q000627:therapeutic use*
chemical_list: D008024:Ligands; D008670:Metals; D014639:Vanadium; D013311:Streptozocin
references: QJM. 2008 May;101(5):351-8
references: 18319296
references: J Inorg Biochem. 2009 Apr;103(4):554-8
references: 19162329
references: Rev Diabet Stud. 2010 Winter;7(4):263-74
references: 21713314
references: ChemMedChem. 2007 Nov;2(11):1607-12
references: 17768733
references: Metabolism. 2006 Feb;55(2):263-70
references: 16423636
references: Cell Biochem Funct. 2003 Jun;21(2):177-82
references: 12736908
references: Gen Physiol Biophys. 2011 Dec;30(4):356-63
references: 22131317
references: J Pediatr Endocrinol Metab. 2005 Oct;18(10):1007-11
references: 16355814
references: Arch Pharm (Weinheim). 2001 Dec;334(12):388-92
references: 11852534
references: BioDrugs. 2006;20(6):341-50
references: 17176121
references: Biochem Biophys Res Commun. 2006 Jul 7;345(3):945-50
references: 16707105
references: Pak J Biol Sci. 2010 Dec 1;13(23):1135-40
references: 21313890
references: Indian J Med Res. 2007 Mar;125(3):217-30
references: 17496352
references: Metabolism. 2000 Mar;49(3):400-10
references: 10726921
references: Biol Trace Elem Res. 2004 Feb;97(2):163-82
references: 14985626
references: Biol Trace Elem Res. 2012 Jun;147(1-3):195-9
references: 22161314
references: J Inorg Biochem. 2011 Aug;105(8):1081-5
references: 21726771
references: Exp Diabetes Res. 2011;2011:108328
references: 22144984
references: Clin Invest Med. 1987 Sep;10(5):457-69
references: 3315367
references: Science. 1985 Mar 22;227(4693):1474-7
references: 3156405
references: Maturitas. 2012 Feb;71(2):94-103
references: 22137331
references: Anal Bioanal Chem. 2012 Jan;402(1):277-85
references: 21842199
references: Am J Pathol. 2007 Jan;170(1):240-50
references: 17200197
references: Expert Rev Anticancer Ther. 2006 Sep;6 Suppl 9:S63-74
references: 17004859
references: Biol Trace Elem Res. 2002 Apr;86(1):31-44
references: 12002658
references: J Inorg Biochem. 2009 Apr;103(4):585-9
references: 19203797
references: Curr Diab Rep. 2012 Aug;12(4):414-22
references: 22644874
references: Br J Pharmacol. 1999 Jan;126(2):467-77
references: 10077240
references: J Pharm Pharmacol. 2008 Jan;60(1):99-105
references: 18088510
references: Toxicol Lett. 1984 Nov;23(2):227-31
references: 6334379
references: Diabetes Res Clin Pract. 2000 Jan;47(1):1-13
references: 10660216
references: J Inorg Biochem. 2005 May;99(5):1064-75
references: 15833329
references: Mayo Clin Proc. 2011 May;86(5):444-56
references: 21531886
references: Forensic Sci Int. 2011 Mar 20;206(1-3):e79-81
references: 21130588
references: Magnes Res. 2011 Dec;24(4):196-208
references: 22068015
references: J Inorg Biochem. 2006 Dec;100(12):1925-35
references: 17055061
references: Circulation. 2012 Jul 10;126(2):182-8
references: 22753304