title: Application of liposomes in drug development--focus on gastroenterological targets.
abstract: Over the past decade, liposomes became a focal point in developing drug delivery systems. New liposomes, with novel lipid molecules or conjugates, and new formulations opened possibilities for safely and efficiently treating many diseases including cancers. New types of liposomes can prolong circulation time or specifically deliver drugs to therapeutic targets. This article concentrates on current developments in liposome based drug delivery systems for treating diseases of the gastrointestinal tract. We will review different types and uses of liposomes in the development of therapeutics for gastrointestinal diseases including inflammatory bowel diseases and colorectal cancer.
authors: Department of General Surgery, the Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu Province, People's Republic of China.
authors: Jian-Xin
authors: JX
authors: Zhang
authors: Kun
authors: K
authors: Wang
authors: Zheng-Fa
authors: ZF
authors: Mao
authors: Xin
authors: X
authors: Fan
authors: De-Li
authors: DL
authors: Jiang
authors: Min
authors: M
authors: Chen
authors: Lei
authors: L
authors: Cui
authors: Kang
authors: K
authors: Sun
authors: Sheng-Chun
authors: SC
authors: Dang
mesh_terms: D000818:Animals; D015179:Colorectal Neoplasms / Q000188:drug therapy*; D055808:Drug Discovery / Q000379:methods*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy*; D008081:Liposomes / Q000008:administration & dosage / Q000737:chemistry*
chemical_list: D008081:Liposomes
keywords: colorectal cancer; drug delivery; inflammatory bowel disease; liposome
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