title: The solvothermal synthesis of magnetic iron oxide nanocrystals and the preparation of hybrid poly(L-lactide)-polyethyleneimine magnetic particles.
abstract: We report a simple and green procedure for the preparation of magnetic iron oxide nanocrystals via solvothermal synthesis. The nanocrystal synthesis was carried out under mild conditions in the water-ethanol-oleic acid solvent system with the use of the oleate anion as a surface modifier of nanocrystals and glucose as a reducing agent. Specific conditions for homogenous precipitation achieved in such a reaction system lead to the formation of uniform high-quality nanocrystals down to 5 nm in diameter. The obtained hydrophobic nanocrystals can easily be converted to hydrophilic magnetic nanoparticles by being immobilized in a poly(L-lactide)-polyethyleneimine polymeric matrix. These hybrid nano-constructs may find various biomedical applications, such as magnetic separation, gene transfection and/or magnetic resonance imaging.
authors: Centre for Fine Particles Processing and Nanotechnologies, Institute of Technical Sciences of SASA, Belgrade, Serbia.
authors: Zoran
authors: Z
authors: Stojanović
authors: Mojca
authors: M
authors: Otoničar
authors: Jongwook
authors: J
authors: Lee
authors: Magdalena M
authors: MM
authors: Stevanović
authors: Mintai P
authors: MP
authors: Hwang
authors: Kwan Hyi
authors: KH
authors: Lee
authors: Jonghoon
authors: J
authors: Choi
authors: Dragan
authors: D
authors: Uskoković
mesh_terms: D005290:Ferric Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D060526:Magnetic Fields; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D011091:Polyesters / Q000737:chemistry*; D011094:Polyethyleneimine / Q000737:chemistry*; D012995:Solubility; D013499:Surface Properties; D013696:Temperature
chemical_list: D005290:Ferric Compounds; D058185:Magnetite Nanoparticles; D011091:Polyesters; C000499:ferric oxide; C033616:poly(lactide); D011094:Polyethyleneimine