title: Multifocal motor neuropathy, multifocal acquired demyelinating sensory and motor neuropathy, and other chronic acquired demyelinating polyneuropathy variants.
abstract: Chronic acquired demyelinating neuropathies (CADP) constitute an important group of immune neuromuscular disorders affecting myelin. This article discusses CADP with emphasis on multifocal motor neuropathy, multifocal acquired demyelinating sensory and motor neuropathy, distal acquired demyelinating symmetric neuropathy, and less common variants. Although each of these entities has distinctive laboratory and electrodiagnostic features that aid in their diagnosis, clinical characteristics are of paramount importance in diagnosing specific conditions and determining the most appropriate therapies. Knowledge regarding pathogenesis, diagnosis, and management of these disorders continues to expand, resulting in improved opportunities for identification and treatment.
authors: Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Boulevard, Mail Stop 2012, Kansas City, KS 66160, USA. mdimachkie@kumc.edu
authors: Mazen M
authors: MM
authors: Dimachkie
authors: Richard J
authors: RJ
authors: Barohn
authors: Jonathan
authors: J
authors: Katz
mesh_terms: D003711:Demyelinating Diseases / Q000175:diagnosis* / Q000628:therapy*; D004568:Electrodiagnosis; D049673:History, 20th Century; D006801:Humans; D016756:Immunoglobulins, Intravenous; D008297:Male; D008875:Middle Aged; D009431:Neural Conduction; D010951:Plasma Exchange; D011115:Polyneuropathies / Q000145:classification / Q000175:diagnosis* / Q000266:history / Q000628:therapy*
chemical_list: D016756:Immunoglobulins, Intravenous
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