title: A review on therapeutic potential of Nigella sativa: A miracle herb.
abstract: Nigella sativa (N. sativa) (Family Ranunculaceae) is a widely used medicinal plant throughout the world. It is very popular in various traditional systems of medicine like Unani and Tibb, Ayurveda and Siddha. Seeds and oil have a long history of folklore usage in various systems of medicines and food. The seeds of N. sativa have been widely used in the treatment of different diseases and ailments. In Islamic literature, it is considered as one of the greatest forms of healing medicine. It has been recommended for using on regular basis in Tibb-e-Nabwi (Prophetic Medicine). It has been widely used as antihypertensive, liver tonics, diuretics, digestive, anti-diarrheal, appetite stimulant, analgesics, anti-bacterial and in skin disorders. Extensive studies on N. sativa have been carried out by various researchers and a wide spectrum of its pharmacological actions have been explored which may include antidiabetic, anticancer, immunomodulator, analgesic, antimicrobial, anti-inflammatory, spasmolytic, bronchodilator, hepato-protective, renal protective, gastro-protective, antioxidant properties, etc. Due to its miraculous power of healing, N. sativa has got the place among the top ranked evidence based herbal medicines. This is also revealed that most of the therapeutic properties of this plant are due to the presence of thymoquinone which is major bioactive component of the essential oil. The present review is an effort to provide a detailed survey of the literature on scientific researches of pharmacognostical characteristics, chemical composition and pharmacological activities of the seeds of this plant.
authors: Health Information Technology Department, Jeddah Community College, King Abdulaziz University, Jeddah-21589, Kingdom of Saudi Arabia.
authors: Aftab
authors: A
authors: Ahmad
authors: Asif
authors: A
authors: Husain
authors: Mohd
authors: M
authors: Mujeeb
authors: Shah Alam
authors: SA
authors: Khan
authors: Abul Kalam
authors: AK
authors: Najmi
authors: Nasir Ali
authors: NA
authors: Siddique
authors: Zoheir A
authors: ZA
authors: Damanhouri
authors: Firoz
authors: F
authors: Anwar
mesh_terms: D006801:Humans; D008519:Medicine, Traditional; D031881:Nigella sativa / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry* / Q000494:pharmacology* / Q000627:therapeutic use; D010946:Plants, Medicinal / Q000737:chemistry*; D012106:Research; D012639:Seeds / Q000737:chemistry
chemical_list: D010936:Plant Extracts
keywords: Anti-diabetic; Antioxidant; Black seeds; Habat-ul-Sauda; Miracle herb; Nigella sativa; Ranunculaceae; Thymoquinone; Tibb-e-Nabwi
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