title: [Application of immunospecific drug in the treatment of rotavirus gastroenteritis in children].
abstract: The case records of 120 children older than 4 years with rotavirus infection have been studied. In this group, 22 patients received basic therapy and 98 received complex therapy with cycloferon. Appropriate therapy resulted in rapid positive dynamics of clinical symptoms, the disease outcomes have been improved. Cytokine reaction has been studied as dependent on the treatment method. Positive dynamics of clinical symptoms and cytokine level has been revealed in a group of children having received cycloferon. It is recommended to include cycloferon in the basic therapy of rotavirus diarrhea in children.
authors: A V
authors: AV
authors: Gordeets
authors: S L
authors: SL
authors: Piskunova
authors: S N
authors: SN
authors: Beniova
authors: A A
authors: AA
authors: Chernikova
authors: E M
authors: EM
authors: Zhidkov
mesh_terms: D000166:Acridines / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000097:blood / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D005440:Fluid Therapy; D005759:Gastroenteritis / Q000097:blood / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D006801:Humans; D007369:Interferon Inducers / Q000494:pharmacology / Q000627:therapeutic use*; D007371:Interferon-gamma / Q000097:blood; D016753:Interleukin-10 / Q000097:blood; D012401:Rotavirus; D012400:Rotavirus Infections / Q000097:blood / Q000188:drug therapy* / Q000276:immunology / Q000821:virology; D013607:Tablets
chemical_list: D000166:Acridines; C508609:IL10 protein, human; D007369:Interferon Inducers; D013607:Tablets; D016753:Interleukin-10; D007371:Interferon-gamma; C026430:10-carboxymethyl-9-acridanone