title: Imaging biomarker validation and qualification report: sixth OARSI Workshop on Imaging in Osteoarthritis combined with third OA Biomarkers Workshop.
abstract: The sixth Osteoarthritis Research Society International (OARSI) Workshop on Imaging in Osteoarthritis combined with the third osteoarthritis (OA) Biomarkers Workshop is the first to bring together the imaging and molecular biomarker communities to focus on clinical validation and qualification of OA biomarkers. The workshop was held in Hilton Head, SC, USA, from June 12-14, 2012; 138 attendees participated, including representatives from academia, pharmaceutical and magnetic resonance imaging (MRI) industries, Food and Drug Administration (FDA), and National Institutes of Health (NIH). Presentations and discussions raised awareness, consolidated knowledge, and identified strategies to overcome challenges for the development and application of imaging and biochemical biomarkers in OA research studies and clinical trials.
  
  
  CONCLUSIONS
  The OA research communities need to work alongside regulatory agencies across the world, to qualify and validate new chemical and imaging biomarkers for future research and clinical trials.
authors: Kolling Institute, University of Sydney, Royal North Shore Hospital, Sydney, Australia. David.Hunter@sydney.edu.au
authors: D J
authors: DJ
authors: Hunter
authors: F
authors: F
authors: Eckstein
authors: V B
authors: VB
authors: Kraus
authors: E
authors: E
authors: Losina
authors: L
authors: L
authors: Sandell
authors: A
authors: A
authors: Guermazi
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D002358:Cartilage, Articular / Q000378:metabolism / Q000473:pathology*; D003226:Congresses as Topic; D006801:Humans; D007719:Knee Joint / Q000378:metabolism / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010003:Osteoarthritis / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D015203:Reproducibility of Results
chemical_list: D015415:Biomarkers
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