title: J- vs. H-type assembly: pentamethine cyanine (Cy5) as a near-IR chiroptical reporter.
abstract: The DNA-enabled dimerization of pentamethine cyanine (Cy5) dyes was studied by optical methods. The value of cyanine as a chiroptical reporter using a monomer-to-dimer switch is demonstrated. The specific shape of the CD signal and its high intensity are a result of J-type assembly.
authors: Department of Chemistry and Biochemistry, University of Bern, Freiestrasse 3, CH-3012 Bern, Switzerland.
authors: Larysa I
authors: LI
authors: Markova
authors: Vladimir L
authors: VL
authors: Malinovskii
authors: Leonid D
authors: LD
authors: Patsenker
authors: Robert
authors: R
authors: Häner
mesh_terms: D002232:Carbocyanines / Q000737:chemistry*; D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry*; D019281:Dimerization; D005456:Fluorescent Dyes / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D013050:Spectrometry, Fluorescence
chemical_list: D002232:Carbocyanines; D005456:Fluorescent Dyes; C085321:cyanine dye 5; D004247:DNA