title: Management of insect sting hypersensitivity: an update.
abstract: Reactions to Hymenoptera insect stings are common. While most are self-limited, some induce systemic allergic reactions or anaphylaxis. Prompt recognition, diagnosis, and treatment of these reactions are important for improving quality-of-life and reducing the risk of future sting reactions. This review summarizes the current recommendations to diagnose and treat Hymenoptera sting induced allergic reactions and highlights considerations for various populations throughout the world.
authors: Division of Allergy and Immunology, Arkansas Children's Hospital, Little Rock, AR, USA.
authors: Robert D
authors: RD
authors: Pesek
authors: Richard F
authors: RF
authors: Lockey
keywords: Hymenoptera allergy; insect sting allergy; insect sting hypersensitivity; sting-induced anaphylaxis; venom immunotherapy
references: N Engl J Med. 2004 Nov 4;351(19):1978-84
references: 15525723
references: J Allergy Clin Immunol. 2008 Feb;121(2):519-26
references: 18177694
references: Allergy. 2005 Nov;60(11):1339-49
references: 16197464
references: Curr Opin Allergy Clin Immunol. 2006 Aug;6(4):279-83
references: 16825869
references: Curr Opin Allergy Clin Immunol. 2002 Aug;2(4):353-7
references: 12130951
references: J Allergy Clin Immunol. 1992 Jun;89(6):1189-95
references: 1607552
references: J Allergy Clin Immunol. 1992 Aug;90(2):210-5
references: 1500625
references: J Allergy Clin Immunol. 1981 Jun;67(6):482-4
references: 7346532
references: J Allergy Clin Immunol. 1988 Nov;82(5 Pt 1):828-34
references: 3192866
references: J Allergy Clin Immunol. 2004 Dec;114(6):1410-7
references: 15577846
references: J Allergy Clin Immunol. 2009 Jun;123(6):1371-5
references: 19443022
references: Ann Allergy Asthma Immunol. 2004 Apr;92(4):409-13
references: 15104191
references: J Allergy Clin Immunol. 1988 Oct;82(4):567-76
references: 3171000
references: J Allergy Clin Immunol. 1990 Nov;86(5):775-80
references: 2229842
references: J Proteomics. 2009 Mar 6;72(2):145-54
references: 19344653
references: J Allergy Clin Immunol. 1995 Apr;95(4):824-8
references: 7722162
references: Curr Opin Allergy Clin Immunol. 2006 Aug;6(4):289-93
references: 16825871
references: Pathology. 2006 Aug;38(4):328-32
references: 16916722
references: Ann Allergy. 1988 Jul;61(1):63-8
references: 3389573
references: J Allergy Clin Immunol. 2001 May;107(5):925
references: 11344365
references: J Allergy Clin Immunol. 1991 Sep;88(3 Pt 1):339-48
references: 1890261
references: Allergy. 2009 Sep;64(9):1237-45
references: 19627278
references: J Allergy Clin Immunol. 2004 Oct;114(4):869-86
references: 15480329
references: J Allergy Clin Immunol. 2008 Jan;121(1):256-7
references: 18206512
references: J Allergy Clin Immunol. 1996 Feb;97(2):579-87
references: 8621842
references: Allergy Asthma Proc. 2006 Mar-Apr;27(2):148-50
references: 16724635
references: J Allergy Clin Immunol. 1989 Dec;84(6 Pt 1):967-74
references: 2600328
references: Allergy. 1997 Jun;52(6):680-1
references: 9226070
references: J Allergy Clin Immunol. 1984 Mar;73(3):299-304
references: 6366028
references: J Allergy Clin Immunol. 2009 Feb;123(2):434-42
references: 19117599
references: Curr Opin Allergy Clin Immunol. 2002 Aug;2(4):341-6
references: 12130949
references: Allergy. 2008 Aug;63(8):1077-83
references: 18547290
references: JAMA. 1989 Jul 14;262(2):240-4
references: 2739018
references: J Allergy Clin Immunol. 2000 Feb;105(2 Pt 1):385-90
references: 10669863
references: J Allergy Clin Immunol. 2002 Mar;109(3):556-62
references: 11898006
references: J Allergy Clin Immunol. 2001 May;107(5):897-901
references: 11344359
references: N Engl J Med. 2004 Aug 12;351(7):668-74
references: 15306668
references: Ann Allergy. 1994 Nov;73(5):423-8
references: 7978535
references: J Allergy Clin Immunol. 1989 Aug;84(2):162-7
references: 2760358
references: Clin Exp Allergy. 2009 Jun;39(6):883-9
references: 19364334
references: N Engl J Med. 1990 Dec 6;323(23):1601-3
references: 2098016
references: J Allergy Clin Immunol. 1993 Dec;92(6):831-6
references: 8258617
references: J Allergy Clin Immunol. 1974 Sep;54(3):132-46
references: 4854598
references: Novartis Found Symp. 2004;257:116-28; discussion 128-32, 157-60, 276-85
references: 15025395
references: J Allergy Clin Immunol. 2001 Dec;108(6):1027-32
references: 11742283
references: J Allergy Clin Immunol. 1997 Jul;100(1):11-5
references: 9257781
references: Ann Intern Med. 1980 May;92(5):620-4
references: 7387002
references: Clin Exp Allergy. 1993 Mar;23(3):226-30
references: 8472191
references: J Allergy Clin Immunol. 2000 Apr;105(4):683-91
references: 10756216
references: J Allergy Clin Immunol. 1997 Jan;99(1 Pt 1):153-4
references: 9003225
references: J Allergy Clin Immunol. 1998 Mar;101(3):298-305
references: 9525443
references: N Engl J Med. 1978 Jul 27;299(4):157-61
references: 78446
references: J Allergy Clin Immunol. 1985 Dec;76(6):803-7
references: 3877747
references: J Allergy Clin Immunol. 1984 Feb;73(2):246-52
references: 6699307
references: Curr Opin Allergy Clin Immunol. 2001 Aug;1(4):353-6
references: 11964712
references: Allergy. 1979 Dec;34(6):369-78
references: 546252
references: J Allergy Clin Immunol. 2012 Sep;130(3):822-3
references: 22828415
references: J Allergy Clin Immunol. 1990 Apr;85(4):709-12
references: 2324411
references: J Allergy Clin Immunol. 2009 Mar;123(3):680-6
references: 19135713
references: South Med J. 1981 Nov;74(11):1361-4
references: 7302637
references: Allergy. 2000 Jul;55(7):676-7
references: 10921470
references: J Investig Allergol Clin Immunol. 2006;16(2):79-85
references: 16689180
references: Clin Exp Allergy. 1999 Aug;29(8):1069-74
references: 10457110
references: J Allergy Clin Immunol. 2011 Apr;127(4):852-4.e1-23
references: 21458655
references: Curr Opin Allergy Clin Immunol. 2008 Aug;8(4):330-7
references: 18596590
references: Lancet. 2003 Mar 22;361(9362):1001-6
references: 12660058
references: Immunol Allergy Clin North Am. 2007 May;27(2):261-72, vii
references: 17493502
references: J Allergy Clin Immunol. 2001 May;107(5):902-6
references: 11344360
references: J Allergy Clin Immunol. 1998 May;101(5):606-12
references: 9600496
references: Allergy Asthma Immunol Res. 2012 Sep;4(5):284-9
references: 22950034
references: Lancet. 2001 Feb 3;357(9253):361-2
references: 11211002
references: J Fla Med Assoc. 1977 Apr;64(4):247-54
references: 557531
references: J Allergy Clin Immunol. 1988 Sep;82(3 Pt 1):370-81
references: 3170986
references: J Allergy Clin Immunol. 1997 Aug;100(2):182-4
references: 9275138