title: Laparoscopic versus open multivisceral resection for primary colorectal cancer: comparison of perioperative outcomes.
abstract: BACKGROUND
  The role of laparoscopic surgery for locally advanced colorectal cancer invading or adhering to neighboring organs is controversial. This study evaluated the safety and feasibility of laparoscopic multivisceral resection for colorectal cancer.
  
  
  METHODS
  This study included 126 patients who underwent multivisceral resection for primary colorectal cancer invading or adhering to neighboring organs or structures between July 2005 and November 2012 at our institution. Perioperative outcomes were compared between laparoscopic and open resections.
  
  
  RESULTS
  Laparoscopic and open multivisceral resections were performed in 60 and 66 patients, respectively. Conversion to open surgery occurred in 6.7 % of patients. The median operative time was significantly longer (271 vs. 227 min), but the median blood loss was significantly less (40 vs. 205 mL), in the laparoscopic compared with the open group. The R0 resection rate of the primary tumor (95 vs. 98.5 %), number of lymph nodes harvested (18 vs. 18), and postoperative complications (28 vs. 24 %) were comparable between the groups. The median length of hospital stay was significantly shorter (13.5 vs. 18 days) in the laparoscopic compared with the open group.
  
  
  CONCLUSIONS
  Laparoscopic multivisceral resection for colorectal cancer invading or adhering to neighboring organs is safe and feasible in selected patients.
authors: Gastroenterological Center, Department of Gastroenterological Surgery, Cancer Institute Hospital, 3-10-6, Ariake, Koto-ku, Tokyo, 135-8550, Japan.
authors: Yasutomo
authors: Y
authors: Nagasue
authors: Takashi
authors: T
authors: Akiyoshi
authors: Masashi
authors: M
authors: Ueno
authors: Yosuke
authors: Y
authors: Fukunaga
authors: Satoshi
authors: S
authors: Nagayama
authors: Yoshiya
authors: Y
authors: Fujimoto
authors: Tsuyoshi
authors: T
authors: Konishi
authors: Toshiya
authors: T
authors: Nagasaki
authors: Jun
authors: J
authors: Nagata
authors: Toshiki
authors: T
authors: Mukai
authors: Atsushi
authors: A
authors: Ikeda
authors: Riki
authors: R
authors: Ono
authors: Toshiharu
authors: T
authors: Yamaguchi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000473:pathology / Q000601:surgery*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D016896:Treatment Outcome; D014781:Viscera / Q000601:surgery*
references: Surg Endosc. 2011 May;25(5):1409-14
references: 20953880
references: J Korean Soc Coloproctol. 2011 Feb;27(1):21-6
references: 21431093
references: Br J Surg. 2008 Feb;95(2):199-205
references: 17696215
references: Lancet Oncol. 2010 Jul;11(7):637-45
references: 20610322
references: N Engl J Med. 2004 May 13;350(20):2050-9
references: 15141043
references: World J Surg Oncol. 2012 Feb 15;10:39
references: 22336589
references: Lancet Oncol. 2009 Jan;10(1):44-52
references: 19071061
references: J Clin Oncol. 2007 Jul 20;25(21):3061-8
references: 17634484
references: Lancet Oncol. 2005 Jul;6(7):477-84
references: 15992696
references: Surg Endosc. 2012 Feb;26(2):493-500
references: 22011939
references: Lancet. 2005 May 14-20;365(9472):1718-26
references: 15894098
references: J Gastrointest Surg. 2009 Mar;13(3):521-5
references: 19011946
references: J Natl Cancer Inst. 2001 Apr 18;93(8):583-96
references: 11309435
references: Ann Surg. 2010 Jul;252(1):84-9
references: 20562603
references: Dis Colon Rectum. 2004 Dec;47(12):2055-63
references: 15657654
references: Colorectal Dis. 2011 Oct;13(10):e349-52
references: 21689365
references: Colorectal Dis. 2011 Feb;13(2):138-43
references: 20653697
references: Surg Endosc. 2004 Aug;18(8):1163-85
references: 15457376
references: Dis Colon Rectum. 2009 Aug;52(8):1381-6
references: 19617748
references: Langenbecks Arch Surg. 2012 Jan;397(1):75-84
references: 21968828
references: Ann Surg. 2002 Feb;235(2):217-25
references: 11807361
references: Ann Surg. 2007 Oct;246(4):655-62; discussion 662-4
references: 17893502
references: Langenbecks Arch Chir. 1987;371(4):281-90
references: 3437791
references: Surg Endosc. 2013 Jan;27(1):1-10
references: 23239291