title: Baseline characteristics of European and non-European adult patients with attention deficit hyperactivity disorder participating in a placebo-controlled, randomized treatment study with atomoxetine.
abstract: BACKGROUND
  Attention deficit/hyperactivity disorder (ADHD) often presents as an impairing lifelong condition in adults; yet it is currently underdiagnosed and undertreated in many European countries. This analysis examines the characteristics of adult patients with ADHD in a European (EUR) and non-European (NE) patient population.
  
  
  METHODS
  Baseline data from the open-label treatment period of a randomized trial of atomoxetine in adult patients with ADHD (N=2017; EUR, n=1217; NE, n=800) were examined. All patients who were enrolled were included in the baseline analyses.
  
  
  RESULTS
  The demographics for patients in the EUR and NE groups were comparable. Patients in the EUR group had a somewhat lower percentage of prior exposure to psychostimulants compared with the NE group (32.7% vs. 38.9%, p=.0049). Scores on the Conners' Adult ADHD Rating Scale-Investigator Rated: Screening Version with adult ADHD prompts (18-item total, inattentive and hyperactive/impulsive subscales, and index) were comparable. The adult ADHD Quality of Life-Life Outlook and Life Productivity domain scores were significantly different between groups (p≤.0004). The EuroQol-5 Dimension United Kingdom and United States population-based index scores and Health State score were comparable between groups.
  
  
  CONCLUSIONS
  Adults with ADHD in Europe present similar demographics and baseline characteristics to those outside Europe and hence, study results outside Europe may be generalizable to patients in Europe.
  
  
  BACKGROUND
  Clinicaltrials.gov, NCT00700427.
authors: Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285, USA. upadhyayahp@lilly.com.
authors: Himanshu
authors: H
authors: Upadhyaya
authors: Lenard A
authors: LA
authors: Adler
authors: Miguel
authors: M
authors: Casas
authors: Alexandra
authors: A
authors: Kutzelnigg
authors: David
authors: D
authors: Williams
authors: Yoko
authors: Y
authors: Tanaka
authors: Jody
authors: J
authors: Arsenault
authors: Rodrigo
authors: R
authors: Escobar
authors: Albert J
authors: AJ
authors: Allen
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