title: Atrogin-1/MAFbx, a muscle-specific ubiquitin ligase, is highly expressed in the smooth muscle of the chicken gizzard.
abstract: This study was conducted to investigate the expression of atrogin-1/MAFbx, a muscle-specific ubiquitin ligase, in the smooth muscle of the chicken gizzard. Atrogin-1/MAFbx mRNA expression was detected in the skeletal muscle, heart (cardiac muscle), gizzard (smooth muscle), brain, and liver of chicks, with highest expression in the smooth muscle of the gizzard. The expression of atrogin-1/MAFbx mRNA in the smooth muscle of the gizzard was increased by fasting (24 h), and this increase was reduced by refeeding (2 h). These results indicate that atrogin-1/MAFbx mRNA is highly expressed in the smooth muscle of the chicken gizzard, and that the expression of it is regulated by nutritional conditions.
authors: Animal Physiology and Nutrition Division, National Institute of Livestock and Grassland Science, Tsukuba, Japan. kaznaka@affrc.go.jp
authors: Kazuki
authors: K
authors: Nakashima
authors: Aiko
authors: A
authors: Ishida
authors: Masaya
authors: M
authors: Katsumata
mesh_terms: D000818:Animals; D002645:Chickens; D004435:Eating; D005215:Fasting; D015971:Gene Expression Regulation, Enzymologic; D005895:Gizzard, Avian / Q000201:enzymology*; D008297:Male; D009130:Muscle, Smooth / Q000201:enzymology*; D009928:Organ Specificity; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D044843:SKP Cullin F-Box Protein Ligases / Q000235:genetics*
chemical_list: D012333:RNA, Messenger; D044843:SKP Cullin F-Box Protein Ligases