title: T-cell prolymphocytic leukaemia (T-PLL): a rare disease with a grave prognosis.
abstract: T-cell prolymphocytic leukaemia (T-PLL) is an extremely uncommon haematological malignancy that has an aggressive course and a grave prognosis. We describe a patient who presented with lymphocytosis, scalp erythema, ascites and splenomegaly and was diagnosed with T-PLL. He was treated with alemtuzumab with a good response and was referred for allogeneic stem cell transplantation.
authors: Department of Hematology/Oncology, Staten Island University Hospital, Staten Island, New York, USA. avivek27@gmail.com
authors: Abhirami
authors: A
authors: Vivekanandarajah
authors: Jean Paul
authors: JP
authors: Atallah
authors: Shilpi
authors: S
authors: Gupta
mesh_terms: D000074323:Alemtuzumab; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D015703:Antigens, CD; D000951:Antigens, Neoplasm; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D000074301:CD52 Antigen; D006023:Glycoproteins; D006801:Humans; D015461:Leukemia, Prolymphocytic, T-Cell / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D035583:Rare Diseases; D033581:Stem Cell Transplantation
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D015703:Antigens, CD; D000951:Antigens, Neoplasm; D000970:Antineoplastic Agents; D000074301:CD52 Antigen; C000613862:CD52 protein, human; D006023:Glycoproteins; D000074323:Alemtuzumab
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