title: Carcinoma developing in a branchial cyst.
abstract: BACKGROUND
  The malignant transformation of the branchial cysts epithelium is rare and it represents separate entity called branchiogenic carcinoma.
  
  
  METHODS
  A 55-year-old male with fluctuating mass localized on the right side of the neck, was admitted to the Department of Maxillofacial Surgery, General hospital in Vrbas where cystic tumor 3 cm in its greatest dimension with friable, dark red wall below the front edge of the sternocleidomastoid muscle was revealed. The wall of the tumor was composed of lymphoid tissue with germinal centers. The internal surface of the cyst was lined with thin layered squamous epithelium that showed a transition from the normal, followed by the atypical epithelium, and the in situ carcinoma to the part corresponding to a poor differentiated invasive squamous carcinoma. Following the diagnosis of suspected branchiogenic carcinoma a radical neck dissection was performed. No elements of the tumor had been found in the sampled materials taken from striated muscle tissue, salivary gland tissue and reactive lymph nodes (n = 24). The patient was presented to Oncology Consilium, and radiotherapy was implemented.
  
  
  CONCLUSIONS
  The definitive diagnosis must be based on histological features. A five-year monitoring of the patient is necessary to rule out cervical metastasis of this tumor. It is necessary for a five-year follow-up to rule out cervical metastasis of the tumor.
authors: Department for Pathology, Faculty of Medicine, University of Novi Sad, Serbia. tegeltijadragana@sbb.rs
authors: Dragana
authors: D
authors: Tegeltija
authors: Aleksandra
authors: A
authors: Lovrenski
authors: Milana
authors: M
authors: Panjković
authors: Jovan
authors: J
authors: Marjanov
authors: Golub
authors: G
authors: Samardzija
authors: Nemanja
authors: N
authors: Pejaković
mesh_terms: D001935:Branchioma / Q000150:complications*; D002277:Carcinoma / Q000150:complications*; D006258:Head and Neck Neoplasms / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged