title: Cryptogenic sensory polyneuropathy.
abstract: Chronic sensory or sensorimotor polyneuropathy is a common cause for referral to neurologists. Despite extensive diagnostic testing, up to one-third of these patients remain without a known cause, and are referred to as having cryptogenic sensory peripheral neuropathy. Symptoms progress slowly. On examination, there may be additional mild toe flexion and extension weakness. Electrophysiologic testing and histology reveals axonal neuropathy. Prognosis is usually favorable, as most patients maintain independent ambulation. Besides patient education and reassurance, management is focused on pharmacotherapy for neuropathic pain and physical therapy for balance training, and, occasionally, assistive devices.
authors: Department of Neurology, University of Kansas Medical Center, 3599 Rainbow Boulevard, Kansas City, KS 66160, USA. mpasnoor@kumc.edu
authors: Mamatha
authors: M
authors: Pasnoor
authors: Mazen M
authors: MM
authors: Dimachkie
authors: Richard J
authors: RJ
authors: Barohn
mesh_terms: D000369:Aged, 80 and over; D004568:Electrodiagnosis; D005820:Genetic Testing; D006801:Humans; D008297:Male; D009431:Neural Conduction / Q000502:physiology; D059408:Pain Management; D011115:Polyneuropathies / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D012678:Sensation Disorders / Q000150:complications* / Q000175:diagnosis / Q000628:therapy
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