title: First report of generalized face processing difficulties in möbius sequence.
abstract: Reverse simulation models of facial expression recognition suggest that we recognize the emotions of others by running implicit motor programmes responsible for the production of that expression. Previous work has tested this theory by examining facial expression recognition in participants with Möbius sequence, a condition characterized by congenital bilateral facial paralysis. However, a mixed pattern of findings has emerged, and it has not yet been tested whether these individuals can imagine facial expressions, a process also hypothesized to be underpinned by proprioceptive feedback from the face. We investigated this issue by examining expression recognition and imagery in six participants with Möbius sequence, and also carried out tests assessing facial identity and object recognition, as well as basic visual processing. While five of the six participants presented with expression recognition impairments, only one was impaired at the imagery of facial expressions. Further, five participants presented with other difficulties in the recognition of facial identity or objects, or in lower-level visual processing. We discuss the implications of our findings for the reverse simulation model, and suggest that facial identity recognition impairments may be more severe in the condition than has previously been noted.
authors: Psychology Research Centre, Bournemouth University, Poole, United Kingdom. sbate@bournemouth.ac.uk
authors: Sarah
authors: S
authors: Bate
authors: Sarah Jayne
authors: SJ
authors: Cook
authors: Joseph
authors: J
authors: Mole
authors: Jonathan
authors: J
authors: Cole
mesh_terms: D000328:Adult; D003198:Computer Simulation; D004644:Emotions; D005149:Facial Expression; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020331:Mobius Syndrome / Q000175:diagnosis*; D008953:Models, Anatomic; D010364:Pattern Recognition, Visual; D015203:Reproducibility of Results
references: Cognition. 2009 May;111(2):219-47
references: 19296930
references: Neuron. 2003 Oct 30;40(3):655-64
references: 14642287
references: Cogn Neuropsychol. 2008 May;25(3):395-410
references: 18587702
references: Psychol Sci. 2011 Apr;22(4):464-71
references: 21393576
references: Brain Res Cogn Brain Res. 1996 Mar;3(2):131-41
references: 8713554
references: Neurology. 2003 Aug 12;61(3):327-33
references: 12913192
references: Nat Neurosci. 2000 Nov;3(11):1077-8
references: 11036262
references: Clin Genet. 2006 Aug;70(2):91-7
references: 16879188
references: Soc Neurosci. 2007;2(3-4):167-78
references: 18633815
references: Brain. 1996 Oct;119 ( Pt 5):1647-65
references: 8931587
references: Brain. 1997 Oct;120 ( Pt 10):1763-77
references: 9365369
references: Neuropsychologia. 2005;43(2):260-7
references: 15707910
references: J Cogn Neurosci. 2011 Jul;23(7):1723-40
references: 20617881
references: Psychol Sci. 2008 Oct;19(10):984-5
references: 19000207
references: Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5238-41
references: 20176944
references: J Clin Exp Neuropsychol. 2010 Nov;32(9):1002-16
references: 20437285
references: Neurology. 1995 Sep;45(9):1696-702
references: 7675229
references: Mem Cognit. 2005 Jan;33(1):98-106
references: 15915796
references: J Exp Psychol Learn Mem Cogn. 1999 Jul;25(4):997-1010
references: 10439505
references: Neuropsychologia. 2011 Jul;49(9):2541-52
references: 21601583
references: Psychol Rev. 1968 Nov;75(6):466-77
references: 4973669
references: J Bone Joint Surg Am. 1953 Apr;35-A(2):437-44
references: 13052617
references: Cogn Neuropsychol. 2007 Jun;24(4):419-30
references: 18416499
references: Nat Rev Neurosci. 2001 Sep;2(9):635-42
references: 11533731
references: Brain. 1991 Dec;114 ( Pt 6):2593-609
references: 1782533
references: Psychol Sci. 2000 Jan;11(1):86-9
references: 11228851
references: Neuropsychologia. 2006;44(4):576-85
references: 16169565
references: Trends Cogn Sci. 2006 Oct;10(10):435-41
references: 16949331
references: Biol Psychiatry. 1983 Oct;18(10):1107-25
references: 6317064
references: Cognition. 2005 Jan;94(3):193-213
references: 15617671
references: Soc Neurosci. 2010;5(2):241-51
references: 19882440
references: J Child Psychol Psychiatry. 2001 Feb;42(2):241-51
references: 11280420
references: J Child Psychol Psychiatry. 1997 Oct;38(7):813-22
references: 9363580
references: Brain Cogn. 2003 Jun;52(1):61-9
references: 12812805
references: Cogn Neuropsychol. 2000 Feb 1;17(1):73-87
references: 20945172
references: Cortex. 2008 Jul-Aug;44(7):806-19
references: 18489961
references: Cognition. 2011 Feb;118(2):201-10
references: 21130422
references: J Nerv Ment Dis. 1984 Mar;172(3):174-5
references: 6699632
references: Behav Res Methods. 2012 Jun;44(2):587-605
references: 22012343
references: Scand J Psychol. 1998 Mar;39(1):39-45
references: 9619131
references: Exp Brain Res. 1996 Nov;112(1):103-11
references: 8951412
references: Cogn Neuropsychol. 2009 Jun;26(4):391-411
references: 19693716
references: Cogn Neuropsychol. 2009 Jul;26(5):423-55
references: 19921582