title: [Influence of ethanol-metabolising systems on intensity of lipid peroxidation processes in gastrointestinal tract of rats].
abstract: The effects of some ethanol-metabolising systems (aldehyde dehydrogenase, catalase, cytochrome P450 2E1) on activation of lipid peroxidation (LPO) processes in gastrointestinal tract of rats have been studied using inhibitors of these systems. The intensity of LPO processes was evaluated by thiobarbituric acid-reactive products and chemiluminiscence intensity. It was found, that the acetadehyde metabolism play the main role in the indiction of lipid peroxidation in the gastrointestinal tract of rats.
authors: N É
authors: NÉ
authors: Petushok
authors: T Ch
authors: TCh
authors: Grokhovskaia
authors: N G
authors: NG
authors: Mel'nichenko
authors: S P
authors: SP
authors: Pron'ko
mesh_terms: D000079:Acetaldehyde / Q000378:metabolism; D000444:Aldehyde Dehydrogenase / Q000378:metabolism; D000818:Animals; D002374:Catalase / Q000378:metabolism; D002492:Central Nervous System Depressants / Q000493:pharmacokinetics* / Q000494:pharmacology; D019392:Cytochrome P-450 CYP2E1 / Q000378:metabolism; D000431:Ethanol / Q000493:pharmacokinetics* / Q000494:pharmacology; D041981:Gastrointestinal Tract / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism
chemical_list: D002492:Central Nervous System Depressants; D017392:Thiobarbituric Acid Reactive Substances; D000431:Ethanol; D002374:Catalase; D019392:Cytochrome P-450 CYP2E1; D000444:Aldehyde Dehydrogenase; D000079:Acetaldehyde