title: Ethyl 23-benzyl-8,11,14-trioxa-23,28,29-triaza-penta-cyclo-[19.7.1.0(2,7).0(15,20).0(22,27)]nona-cosa-2,4,6,15(20),16,18,21,26-octa-ene-26-carboxyl-ate.
abstract: The title compound, C33H35N3O5, is the product of the multicomponent condensation of 1-benzyl-4-eth-oxy-carbonyl-piperidin-3-one with 1,5-bis-(2-formyl-phen-oxy)-3-oxapentane and ammonium acetate. The mol-ecule comprises a penta-cyclic system containing the aza-14-crown-4-ether macrocycle, tetra-hydro-pyrimidine, tetra-hydro-pyridine and two benzene rings. The aza-14-crown-4-ether ring adopts a bowl conformation with a dihedral angle of 62.37 (5)° between the benzene rings. The tetra-hydro-pyrimidine ring has an envelope conformation with the chiral C atom as the flap, whereas the tetra-hydro-pyridine ring adopts a distorted chair conformation. Two amino groups are involved in intra-molecular N-H⋯O hydrogen bonds. In the crystal, weak C-H⋯O hydrogen bonds link the mol-ecules into layers parallel to the ab plane.
authors: Department of Chemistry, Vietnam National University, 144 Xuan Thuy, Cau Giay, Hanoi, Vietnam.
authors: Truong Hong
authors: TH
authors: Hieu
authors: Le Tuan
authors: le T
authors: Anh
authors: Anatoly T
authors: AT
authors: Soldatenkov
authors: Vasily G
authors: VG
authors: Vasil'ev
authors: Victor N
authors: VN
authors: Khrustalev
references: Acta Crystallogr Sect E Struct Rep Online. 2012 Jul 1;68(Pt 7):o2165-6
references: 22798837
references: Acta Crystallogr Sect E Struct Rep Online. 2012 May 1;68(Pt 5):o1386-7
references: 22590276
references: Acta Crystallogr Sect E Struct Rep Online. 2012 Oct 1;68(Pt 10):o2848-9
references: 23125652
references: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references: 18156677
references: Acta Crystallogr Sect E Struct Rep Online. 2012 Aug 1;68(Pt 8):o2431-2
references: 22904880
references: Acta Crystallogr Sect E Struct Rep Online. 2012 Jun 1;68(Pt 6):o1588-9
references: 22719399