title: Progress in Pediatrics in 2012: choices in allergy, endocrinology, gastroenterology, hematology, infectious diseases, neurology, nutrition and respiratory tract illnesses.
abstract: In this review, we summarize the progresses in allergy, endocrinology, gastroenterology, hematology, infectious diseases, neurology, nutrition and respiratory tract illnesses that have been published in The Italian Journal of Pediatrics in 2012. The induction of Treg activity by probiotics might be effective for promoting tolerance towards food allergens. Nasal cytology is useful in patients with rhinitis for diagnosing chronic non-allergic non-infectious diseases. Atopic eczema is associated both with an aberrant skin matrix and impaired systemic immune response. Therefore, isolated topical treatment may have suboptimal effect. Diagnostic work-up of exercise-induced anaphylaxis, including exercise challenge test, is necessary to reach a diagnosis. Studies may support a role for nutrition on prevention of asthma and cardiovascular diseases. Clinicians need to early identify adolescent menstrual abnormalities to minimize sequelae, and to promote health information. In Multiple Endocrine Neoplasia type 2B investigations include acetylcholinesterase study of rectal mucosa followed by the molecular analysis of RET mutation. Low adherence to gluten-free diet and osteopenia are common problems in children with diabetes mellitus type 1 and celiac disease. In infantile colic, laboratory tests are usually unnecessary and the treatment is based on reassurance. Prevalence of obesity and stunting is elucidated by several studies. Evidences are growing that dietetic measures are needed to prevent obesity in children with acute leukemia. Treatment studies for infectious diseases show promise for probiotics along with standard triple therapy in children with Helicobacter pilori infection, while zinc has no effect on pneumonia. Educational programs about the proper management of the febrile child are warranted. A new hour-specific total serum bilirubin nomogram has been shown to be able to predict newborns without hyperbilirubinemia after 48 to 72 hours of life. Newborns with hypoxic-ischemic encephalopathy present ECG and cardiac enzymes alterations leading to reduced neonatal survival. Rehabilitation programs including sensory integration therapy and motor performance, may improve activities of daily life in children with developmental coordination disorder. Aerobic exercise training in addition to chest physiotherapy might be useful in children with cystic fibrosis. Studies on effectiveness of leukotriene receptor antagonists, alone or with other drugs in preschool wheezing are needed.
authors: Carlo
authors: C
authors: Caffarelli
authors: Francesca
authors: F
authors: Santamaria
authors: Alessandra
authors: A
authors: Vottero
authors: Sergio
authors: S
authors: Bernasconi
mesh_terms: D000486:Allergy and Immunology / Q000639:trends; D004704:Endocrinology / Q000639:trends; D005762:Gastroenterology / Q000639:trends; D006405:Hematology / Q000639:trends; D006801:Humans; D055552:Infectious Disease Medicine / Q000639:trends; D009462:Neurology / Q000639:trends; D052756:Nutritional Sciences / Q000639:trends; D010372:Pediatrics / Q000639:trends*; D010506:Periodicals as Topic; D015272:Pulmonary Medicine / Q000639:trends
references: Ital J Pediatr. 2012 Sep 05;38:40
references: 22950655
references: Ital J Pediatr. 2012 Sep 14;38:43
references: 22980517
references: Ital J Pediatr. 2012 Mar 19;38:9
references: 22429913
references: Ital J Pediatr. 2012 Jul 23;38:35
references: 22824011
references: Ital J Pediatr. 2012 Jul 23;38:33
references: 22823976
references: Ital J Pediatr. 2012 Aug 02;38:36
references: 22856593
references: Ital J Pediatr. 2012 May 31;38:22
references: 22651129
references: Ital J Pediatr. 2012 Jul 23;38:31
references: 22823927
references: Ital J Pediatr. 2012 Sep 25;38:51
references: 23009215
references: Ital J Pediatr. 2012 Feb 01;38:6
references: 22296875
references: Ital J Pediatr. 2012 Jan 10;38:2
references: 22233967
references: Ital J Pediatr. 2012 Oct 31;38:63
references: 23114016
references: Ital J Pediatr. 2012 Jun 26;38:29
references: 22734451
references: Ital J Pediatr. 2012 Jul 23;38:34
references: 22823993
references: Ital J Pediatr. 2012 Jan 27;38:4
references: 22284631
references: Ital J Pediatr. 2012 Apr 30;38:14
references: 22546072
references: Ital J Pediatr. 2012 Dec 21;38:73
references: 23259704
references: Ital J Pediatr. 2012 Mar 26;38:10
references: 22449104
references: Ital J Pediatr. 2012 Jun 09;38:26
references: 22682479
references: Ital J Pediatr. 2012 Aug 14;38:38
references: 22892329