title: A rheumatoid nodule in an unusual location: mediastinal lymph node.
abstract: Rheumatoid arthritis (RA) is a multisystem inflammatory disease characterised by destructive synovitis and varied extra-articular involvement. Rheumatoid lung nodules are the most common pulmonary manifestations of RA. Rheumatoid nodules in mediastinal lymph nodes are extremely uncommon. We describe a male patient with long-standing RA and subcutaneous rheumatoid nodules presenting with multiple lung nodules and mediastinal lymphadenopathies. Definite histopathology of a lymph node was consistent with necrobiotic granuloma due to RA. Clinicians should be aware of rheumatoid nodules as a potential cause of mediastinal lymphadenopathies, mainly in advanced rheumatoid arthritis.
authors: Department of Rheumatology, Cooper Medical School of Rowan University, Camden, New Jersey, USA. yachouiralph@cooperhealth.edu
authors: Ralph
authors: R
authors: Yachoui
authors: Celine
authors: C
authors: Ward
authors: Mazen
authors: M
authors: Kreidy
mesh_terms: D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000473:pathology; D006099:Granuloma / Q000209:etiology; D006801:Humans; D008168:Lung / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008206:Lymphatic Diseases / Q000209:etiology*; D008297:Male; D008482:Mediastinum / Q000473:pathology*; D055613:Multiple Pulmonary Nodules / Q000209:etiology*; D012218:Rheumatoid Nodule / Q000473:pathology*
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