title: MR enterography in children with Crohn disease: results from the Belgian pediatric Crohn registry (Belcro).
abstract: BACKGROUND
  Magnetic Resonance enterography (MRE) is an imaging modality avoiding ionizing radiation and the discomfort associated with enteroclysis. The results of MRE at diagnosis in the patients of the Belgian pediatric Crohn registry (Belcro) are compared to endoscopical and histological results.
  
  
  METHODS
  Results of MRE, endoscopy and histology were obtained from the medical charts and assigned to one of the following segments: jejunum, ileum, ascending colon, transverse colon, descending colon or rectosigmoid. MRE images were reviewed in a blinded way by 4 radiologists with specific interest in pediatric MRE.
  
  
  RESULTS
  From the Belcro registry, twenty-two patients underwent a MRE during their work-up for Crohn disease. The results of endoscopy, histology and MRE were concordant (either all negative or positive) in the ileum in 16/18 patients and in the rectosigmoid, descending colon, transverse colon and ascending colon in resp 9, 8, 8 and 8/22 patients. In the non-concordant cases (MRE colon negative but endoscopy and/or histology positive), MRE could not reflect the subtle endoscopic or histologic lesions such as erosions that were described.In 4 cases where ileocaecal valve intubation was impossible ileal MRE findings were abnormal. MRE detected ileal stenosis, jejunal lesions and fistula in resp 4/22, 3/22 en 2/22 patients. The 100% and 75% interobserver agreement was resp 50-82% and 773-100% according to the different intestinal segments.
  
  
  CONCLUSIONS
  MRE is a promising imaging modality avoiding radiation in Crohn disease. It should probably become the technique of first choice for the evaluation of extensive small bowel disease in children with Crohn disease.
authors: Paediatric Gastroenterology Jessaziekenhuis, Hasselt, Belgium. philippe.alliet@jessazh.be
authors: P
authors: P
authors: Alliet
authors: J
authors: J
authors: Desimpelaere
authors: B
authors: B
authors: Hauser
authors: E
authors: E
authors: Janssens
authors: J
authors: J
authors: Khamis
authors: M
authors: M
authors: Lewin
authors: E
authors: E
authors: De Greef
authors: F
authors: F
authors: Smets
authors: I
authors: I
authors: Paquot
authors: G
authors: G
authors: Veereman
authors: G
authors: G
authors: Souverijns
mesh_terms: D000293:Adolescent; D001530:Belgium; D002648:Child; D003424:Crohn Disease / Q000473:pathology*; D016099:Endoscopy, Gastrointestinal / Q000379:methods* / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007422:Intestines / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D015588:Observer Variation; D012042:Registries