title: Evidence-based recommendations for the prescription of exercise for major depressive disorder.
abstract: Major depressive disorder (MDD) is a source of great disease burden, due in part to the limited accessibility and effectiveness of current treatments. Although current treatments are efficacious in a segment of the population with MDD, there is a clear need for alternative and augmentation treatment strategies. Exercise is one such alternative treatment option. Research has shown exercise to be efficacious as both a stand-alone and an augmentation therapy. As a result, exercise is now included in the American Psychiatric Association's treatment recommendations. The purpose of this article is to provide clinicians with a knowledge base to prescribe exercise to their patients. The authors describe the evidence supporting the use of exercise in the treatment of MDD, provide evidence-based recommendations for prescribing exercise, and address practical considerations related to prescribing exercise in real-world treatment settings.
authors: Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390-9119, USA. chad.rethorst@utsouthwestern.edu
authors: Chad D
authors: CD
authors: Rethorst
authors: Madhukar H
authors: MH
authors: Trivedi
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000523:psychology / Q000628:therapy*; D019317:Evidence-Based Medicine; D015444:Exercise / Q000523:psychology; D006801:Humans; D010555:Personality Inventory / Q000706:statistics & numerical data; D055656:Prescriptions; D011594:Psychometrics; D016032:Randomized Controlled Trials as Topic; D055070:Resistance Training; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents