title: Antioxidant potential of the blood in men with obstructive sleep breathing disorders.
abstract: We studied the state of the LPO-antioxidant defense system in men aged from 46 to 55 years. The main group included patients with obstructive sleep breathing disorders. The state of the antioxidant defense system was assessed by measuring the blood levels of LPO substrates with conjugated double bonds, conjugated dienes, ketodienes and conjugated trienes, MDA, retinol, α-tocopherol, reduced and oxidized glutathione, SOD activity, and the level of total antioxidant activity of blood. Calculation of antioxidant potential helps to identify the processes of "oxidative stress" in the main group, which is a pathogenetic substantiation for including antioxidant drugs in the complex therapy of patients with OSBD.
authors: Research Center of Family Health Protection and Human Reproduction Problems, Siberian Division of Russian Academy of Medical Sciences, Irkutsk, Russia.
authors: L I
authors: LI
authors: Kolesnikova
authors: I M
authors: IM
authors: Madaeva
authors: N V
authors: NV
authors: Semenova
authors: B Ya
authors: BY
authors: Vlasov
authors: L A
authors: LA
authors: Grebenkina
authors: M A
authors: MA
authors: Darenskaya
authors: M I
authors: MI
authors: Dolgikh
mesh_terms: D000975:Antioxidants / Q000378:metabolism*; D019803:Glutathione Disulfide / Q000097:blood; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D020181:Sleep Apnea, Obstructive / Q000097:blood*; D013482:Superoxide Dismutase / Q000097:blood; D014801:Vitamin A / Q000097:blood; D024502:alpha-Tocopherol / Q000097:blood
chemical_list: D000975:Antioxidants; D014801:Vitamin A; D008315:Malondialdehyde; D013482:Superoxide Dismutase; D024502:alpha-Tocopherol; D019803:Glutathione Disulfide