title: Long-term risk of glaucoma after congenital cataract surgery.
abstract: OBJECTIVE
  To report the long-term risk of glaucoma development in children following congenital cataract surgery.
  
  
  METHODS
  Retrospective interventional consecutive case series.
  
  
  METHODS
  We retrospectively reviewed the records of 62 eyes of 37 children who underwent congenital cataract surgery when <7 months of age by the same surgeon using a limbal approach. The Kaplan-Meier method was used to calculate the probability of an eye's developing glaucoma and/or becoming a glaucoma suspect over time.
  
  
  RESULTS
  The median age of surgery was 2.0 months and the median follow-up after cataract surgery was 7.9 years (range, 3.2-23.5 years). Nine eyes (14.5%) developed glaucoma a median of 4.3 months after cataract surgery and an additional 16 eyes (25.8%) were diagnosed as glaucoma suspects a median of 8.0 years after cataract surgery. The probability of an eye's developing glaucoma was estimated to be 19.5% (95% CI: 10.0%-36.1%) by 10 years after congenital cataract surgery. When the probability of glaucoma and glaucoma suspect were combined, the risk increased to 63.0% (95% CI: 43.6%-82.3%).
  
  
  CONCLUSIONS
  Long-term monitoring of eyes after congenital cataract surgery is important because we estimate that nearly two thirds of these eyes will develop glaucoma or become glaucoma suspects by 10 years after cataract surgery.
authors: Department of Ophthalmology, Emory University, Atlanta, GA 30322, USA. slamber@emory.edu
authors: Scott R
authors: SR
authors: Lambert
authors: Amitabh
authors: A
authors: Purohit
authors: Hillary M
authors: HM
authors: Superak
authors: Michael J
authors: MJ
authors: Lynn
authors: Allen D
authors: AD
authors: Beck
mesh_terms: D002386:Cataract / Q000151:congenital*; D002387:Cataract Extraction / Q000009:adverse effects*; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D015994:Incidence; D007223:Infant; D007429:Intraocular Pressure / Q000502:physiology; D053208:Kaplan-Meier Estimate; D019654:Lens Implantation, Intraocular; D009798:Ocular Hypertension / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D011336:Probability; D012189:Retrospective Studies; D012307:Risk Factors; D014065:Tonometry, Ocular; D014792:Visual Acuity / Q000502:physiology
references: Br J Ophthalmol. 2009 Mar;93(3):337-41
references: 19019924
references: J Glaucoma. 2005 Jun;14(3):181-5
references: 15870597
references: J AAPOS. 2006 Apr;10(2):117-23
references: 16678745
references: Acta Ophthalmol Scand. 1999 Dec;77(6):677-80
references: 10634562
references: Graefes Arch Clin Exp Ophthalmol. 2002 Mar;240(3):176-9
references: 11935274
references: Arch Ophthalmol. 2012 Mar;130(3):300-5
references: 22084157
references: Ophthalmology. 2011 Dec;118(12):2330-4
references: 21925737
references: Br J Ophthalmol. 2006 Sep;90(9):1103-6
references: 16707519
references: Arch Ophthalmol. 1995 Sep;113(9):1200-2
references: 7661757
references: Ophthalmologica. 2005 Mar-Apr;219(2):72-9
references: 15802930
references: J AAPOS. 2006 Feb;10(1):30-6
references: 16527677
references: Arch Ophthalmol. 2002 Jun;120(6):701-13; discussion 829-30
references: 12049574
references: Arch Ophthalmol. 2010 Jul;128(7):810-8
references: 20457949
references: Ophthalmology. 1991 May;98(5):670-4
references: 2062500
references: Am J Ophthalmol. 2011 Mar;151(3):434-41.e1
references: 21236412
references: J AAPOS. 2006 Feb;10(1):54-7
references: 16527681
references: Arch Ophthalmol. 2004 Dec;122(12):1819-25
references: 15596586
references: Arch Ophthalmol. 2004 Jul;122(7):1070-4
references: 15249380
references: Acta Ophthalmol Scand. 2000 Feb;78(1):65-70
references: 10726793
references: J Pediatr Ophthalmol Strabismus. 1994 Nov-Dec;31(6):355-60; discussion 361
references: 7714698
references: J AAPOS. 2000 Feb;4(1):33-9
references: 10675869
references: Invest Ophthalmol Vis Sci. 1996 Jul;37(8):1532-8
references: 8675395
references: Am J Ophthalmol. 2008 Jul;146(1):1-7
references: 18407241
references: J Pediatr Ophthalmol Strabismus. 1997 Mar-Apr;34(2):88-95
references: 9083953
references: Am J Ophthalmol. 2004 Jan;137(1):30-7
references: 14700641
references: Br J Ophthalmol. 2009 Sep;93(9):1200-3
references: 19429583
references: Arch Ophthalmol. 2011 Sep;129(9):1132-8
references: 21911662
references: Invest Ophthalmol Vis Sci. 2008 May;49(5):1791-6
references: 18223251
references: Ophthalmology. 2008 Jun;115(6):1013-1018.e2
references: 18164065
references: Am J Ophthalmol. 2007 Oct;144(4):502-6
references: 17698023
references: Br J Ophthalmol. 2004 Jul;88(7):905-10
references: 15205235
references: Br J Ophthalmol. 2007 Dec;91(12):1627-30
references: 17475699
references: Ophthalmology. 2013 Apr;120(4):e21-7
references: 23395545
references: J AAPOS. 2001 Aug;5(4):250-4
references: 11507585