title: FYPO: the fission yeast phenotype ontology.
abstract: BACKGROUND
  To provide consistent computable descriptions of phenotype data, PomBase is developing a formal ontology of phenotypes observed in fission yeast.
  
  
  RESULTS
  The fission yeast phenotype ontology (FYPO) is a modular ontology that uses several existing ontologies from the open biological and biomedical ontologies (OBO) collection as building blocks, including the phenotypic quality ontology PATO, the Gene Ontology and Chemical Entities of Biological Interest. Modular ontology development facilitates partially automated effective organization of detailed phenotype descriptions with complex relationships to each other and to underlying biological phenomena. As a result, FYPO supports sophisticated querying, computational analysis and comparison between different experiments and even between species.
  
  
  BACKGROUND
  FYPO releases are available from the Subversion repository at the PomBase SourceForge project page (https://sourceforge.net/p/pombase/code/HEAD/tree/phenotype_ontology/). The current version of FYPO is also available on the OBO Foundry Web site (http://obofoundry.org/).
authors: Cambridge Systems Biology Centre and Department of Biochemistry, University of Cambridge, Sanger Building, 80 Tennis Court Road, Cambridge CB2 1GA, UK. mah79@cam.ac.uk
authors: Midori A
authors: MA
authors: Harris
authors: Antonia
authors: A
authors: Lock
authors: Jürg
authors: J
authors: Bähler
authors: Stephen G
authors: SG
authors: Oliver
authors: Valerie
authors: V
authors: Wood
mesh_terms: D064229:Biological Ontologies; D030541:Databases, Genetic; D063990:Gene Ontology; D010641:Phenotype; D012568:Schizosaccharomyces / Q000235:genetics*
references: Nat Biotechnol. 2007 Nov;25(11):1251-5
references: 17989687
references: Genome Biol. 2005;6(5):R44
references: 15892872
references: Nat Genet. 2000 May;25(1):25-9
references: 10802651
references: Nucleic Acids Res. 2011 Jan;39(Database issue):D507-13
references: 21030441
references: Trends Ecol Evol. 2007 Jul;22(7):345-50
references: 17416439
references: Nucleic Acids Res. 2012 Jan;40(Database issue):D695-9
references: 22039153
references: Nucleic Acids Res. 2010 Jan;38(Database issue):D249-54
references: 19854951
references: Nucleic Acids Res. 2009 Jan;37(Database issue):D515-9
references: 18974179
references: Nat Biotechnol. 2010 Jun;28(6):617-623
references: 20473289
references: BMC Genomics. 2006 Nov 30;7:303
references: 17137508
references: Bioinformatics. 2012 Jul 1;28(13):1783-9
references: 22539675
references: Wiley Interdiscip Rev Syst Biol Med. 2009 Nov-Dec;1(3):390-399
references: 20052305
references: Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:7069-72
references: 19964203
references: DNA Repair (Amst). 2009 May 1;8(5):672-9
references: 19264558
references: Nucleic Acids Res. 2010 Jan;38(Database issue):D433-6
references: 19906697
references: Nature. 2002 Feb 21;415(6874):871-80
references: 11859360
references: Genes Cells. 2007 May;12(5):677-92
references: 17535257
references: Genes Dev. 2008 Nov 15;22(22):3184-95
references: 19056896
references: BMC Bioinformatics. 2011 Jan 05;12:6
references: 21208450
references: Mol Cell Biol. 2002 Jul;22(13):4598-606
references: 12052869
references: Cell. 2012 Oct 26;151(3):671-83
references: 23101633
references: Genome Biol. 2010 Jan 08;11(1):R2
references: 20064205
references: Bioinformatics. 2007 Aug 15;23(16):2198-200
references: 17545183
references: Cell. 1995 Jan 27;80(2):187-97
references: 7834739
references: Nature. 2006 Oct 19;443(7113):818-22
references: 17051209
references: Nature. 1990 Mar 22;344(6264):355-7
references: 2107403
references: Nucleic Acids Res. 2012 Jan;40(Database issue):D559-64
references: 22102568
references: Nucleic Acids Res. 2011 Jan;39(Database issue):D822-9
references: 21036866