title: Total synthesis of starfish saponin goniopectenoside B.
abstract: Star quality: Goniopectenoside B, a minor asterosaponin from starfish Goniopecten demonstrans with antifouling activity, has been synthesized in a convergent 21 steps and in 4.3 % overall yield starting from adrenosterone. This represents the first synthesis of a complex asterosaponin, which are ubiquitous and characteristic in starfish as defense chemicals (see figure).
authors: State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, PR China.
authors: Guozhi
authors: G
authors: Xiao
authors: Biao
authors: B
authors: Yu
mesh_terms: D000818:Animals; D057219:Biofouling / Q000517:prevention & control*; D015394:Molecular Structure; D012503:Saponins / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013215:Starfish / Q000737:chemistry* / Q000502:physiology; D013256:Steroids / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D012503:Saponins; D013256:Steroids; C585427:goniopectenoside B