title: Successful treatment of nonunion with teriparatide after failed ankle arthrodesis for Charcot arthropathy.
abstract: We describe a case of successful treatment to nonunion after multiple arthrodesis operations for Charcot arthropathy with teriparatide. We describe the case of a 25-year-old woman with severe Type I diabetes mellitus that resulted in nonunion after multiple arthrodesis operations for Charcot arthropathy. The woman sustained a femoral shaft fracture for which she underwent surgery with intramedullary nail fixation. Immediately after surgery, an empiric course of teriparatide was initiated. Femoral shaft fracture healing was observed after 2 weeks, and the woman was able to walk 12 weeks after the surgery, at which point plain film and computed tomography images revealed complete union of the ankle.
authors: Osaka City General Hospital, 2-13-22, Miyakojima hondori, Miyakojimaku, Osaka, Japan, tamaik1983_s58_04_22@yahoo.co.jp.
authors: K
authors: K
authors: Tamai
authors: K
authors: K
authors: Takamatsu
authors: K
authors: K
authors: Kazuki
mesh_terms: D000328:Adult; D000843:Ankle Joint / Q000000981:diagnostic imaging / Q000601:surgery*; D001174:Arthrodesis; D001177:Arthropathy, Neurogenic / Q000209:etiology / Q000601:surgery*; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D005260:Female; D005264:Femoral Fractures / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D005594:Fracture Fixation, Intramedullary / Q000379:methods; D005599:Fractures, Ununited / Q000517:prevention & control; D006801:Humans; D011859:Radiography; D019379:Teriparatide / Q000627:therapeutic use*; D017211:Treatment Failure; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D050071:Bone Density Conservation Agents; D019379:Teriparatide
references: Injury. 2007 Mar;38 Suppl 1:S49-62
references: 17383486
references: J Bone Miner Res. 2010 Feb;25(2):404-14
references: 19594305
references: HSS J. 2009 Sep;5(2):149-53
references: 19290582
references: Clin Podiatr Med Surg. 1998 Jan;15(1):11-9
references: 9463765
references: Osteoporos Int. 2010 Jun;21(6):1059-63
references: 19859645
references: J Shoulder Elbow Surg. 2010 Oct;19(7):e22-8
references: 20846618
references: Aging Clin Exp Res. 2007 Aug;19(4 Suppl):30-1
references: 18182890
references: Bone. 2009 Feb;44(2):275-86
references: 19010455
references: J Spinal Disord Tech. 2010 Apr;23(2):151-5
references: 20051918
references: J Bone Joint Surg Am. 1998 Mar;80(3):365-9
references: 9531204
references: Osteoporos Int. 2012 Dec;23(12):2897-900
references: 23076681
references: Osteoporos Int. 2002;13(4):267-77
references: 12030541
references: J Am Acad Orthop Surg. 2006;14(10 Spec No.):S145-51
references: 17003188
references: J Bone Joint Surg Am. 2000 Jul;82-A(7):939-50
references: 10901308
references: J Bone Miner Res. 2003 Nov;18(11):1932-41
references: 14606504
references: Endocr Pract. 2004 May-Jun;10(3):293
references: 15382326