title: Modern diagnosis of Trichomonas vaginalis infection.
abstract: Recent advances in tests for the sexually transmitted protozoan parasite Trichomonas vaginalis have increased opportunities for diagnosis and treatment of this important sexually transmitted infection. This review summarises currently available tests, highlighting their performance characteristics, advantages and limitations. The recent development of molecular tests for the detection of T vaginalis, including rapid antigen detection and nucleic acid amplification tests, has significantly improved the quality of diagnostics for trichomoniasis, particularly in women. In light of the expanded menu of testing options now available, improved recognition and better control of trichomoniasis are in sight, which should enable the eventual reduction of adverse reproductive consequences associated with T vaginalis infection.
authors: Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA. mmhobbs@med.unc.edu
authors: Marcia M
authors: MM
authors: Hobbs
authors: Arlene C
authors: AC
authors: Seña
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D010274:Parasitology / Q000379:methods*; D012749:Sexually Transmitted Diseases / Q000175:diagnosis* / Q000469:parasitology; D014245:Trichomonas Infections / Q000175:diagnosis* / Q000469:parasitology; D014246:Trichomonas vaginalis / Q000235:genetics / Q000302:isolation & purification*
keywords: DIAGNOSIS; LABORATORY METHODS; MOLECULAR TECHNIQUES; TESTING; TRICHOMONAS
references: Clin Infect Dis. 2007 Jan 1;44(1):13-22
references: 17143809
references: J Clin Microbiol. 2009 Jan;47(1):59-63
references: 18987174
references: J Infect Dis. 2003 Aug 1;188(3):465-8
references: 12870131
references: Expert Rev Mol Diagn. 2011 Sep;11(7):679-88
references: 21902528
references: Diagn Microbiol Infect Dis. 2012 Sep;74(1):49-53
references: 22727836
references: J Glob Infect Dis. 2012 Jan;4(1):22-5
references: 22529623
references: Sex Transm Dis. 2000 Apr;27(4):241-2
references: 10782748
references: Sex Transm Dis. 2011 Sep;38(9):828-32
references: 21844738
references: Sex Transm Dis. 2011 Mar;38(3):163-6
references: 20842073
references: J Clin Pathol. 2010 Mar;63(3):249-53
references: 20203225
references: Am J Obstet Gynecol. 2003 Feb;188(2):354-6
references: 12592239
references: Sex Transm Infect. 2004 Jun;80(3):201-3
references: 15170003
references: Clin Infect Dis. 2007 Jul 15;45(2):194-8
references: 17578778
references: Sex Transm Dis. 2010 Jul;37(7):460-6
references: 20562586
references: J Clin Microbiol. 2011 Mar;49(3):866-9
references: 21248097
references: Am J Obstet Gynecol. 2009 Feb;200(2):188.e1-7
references: 19185101
references: J Clin Microbiol. 2008 Oct;46(10):3467-9
references: 18685008
references: J Reprod Immunol. 2009 Dec;83(1-2):185-9
references: 19850356
references: J Clin Microbiol. 2011 Dec;49(12):4106-11
references: 21940475
references: Diagn Cytopathol. 2005 Jun;32(6):341-4
references: 15880709
references: J Infect Dis. 2007 Mar 1;195(5):698-702
references: 17262712
references: Sex Transm Infect. 2013 Jun;89(4):305-7
references: 23093735
references: J Clin Microbiol. 2013 Mar;51(3):1037-9
references: 23325818
references: Int J STD AIDS. 2003 Jan;14(1):28-9
references: 12590789
references: J Urol. 1993 Jun;149(6):1455-8
references: 8501787
references: J Infect Dis. 2005 Dec 15;192(12):2039-44
references: 16288365
references: Sex Transm Dis. 2012 Sep;39(9):671-7
references: 22902662
references: J Clin Microbiol. 2006 Nov;44(11):3994-9
references: 16971646
references: Sex Transm Infect. 2013 Sep;89(6):504-8
references: 23354525