title: [Consensus statement on the clinical management of human immunodeficiency virus-associated neurocognitive disorders].
abstract: OBJECTIVE
  To develop a consensus document containing clinical recommendations for the management of human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND).
  
  
  METHODS
  We assembled a panel of experts appointed by GeSIDA and the Secretariat of the National AIDS Plan (PNS), including internal medicine physicians with expertise in the field of HIV, neuropsychologists, neurologists and neuroradiologists. Scientific information was reviewed to October 2012 in publications and conference papers. In support of the recommendations using two levels of evidence: the strength of the recommendation in the opinion of the experts (A, B, C) and the level of empirical evidence (I, II, III), two levels based on the criteria of the Infectious Disease Society of America, already used in previous documents GeSIDA/SPNS.
  
  
  RESULTS
  Multiple recommendations for the clinical management of these disorders are provided, including two graphics algorithms, considering both the diagnostic and possible therapeutic strategies.
  
  
  CONCLUSIONS
  Neurocognitive disorders associated with HIV infection is currently highly prevalent, are associated with a decreased quality of life and daily activities, and given the possibility of occurrence of an increase in the coming years, there is a need to adequately manage these disorders, from a diagnostic as well as therapeutic point of view, and always from a multidisciplinary perspective.
authors: Daniel
authors: D
authors: Podzamczer Palter
authors: José A
authors: JA
authors: Muñoz-Moreno
authors: Daniel
authors: D
authors: Alcolea Rodríguez
authors: Carlos
authors: C
authors: Alonso Villaverde
authors: Antonio
authors: A
authors: Antela López
authors: Jordi
authors: J
authors: Blanch Andreu
authors: José Luis
authors: JL
authors: Casado Osorio
authors: M José
authors: MJ
authors: Galindo Puerto
authors: Maite
authors: M
authors: Garolera i Freixa
authors: Jaime
authors: J
authors: Locutura Rupérez
authors: Albert
authors: A
authors: Lleó Bisa
authors: Anna
authors: A
authors: Prats París
authors: Ignacio
authors: I
authors: Pérez-Valero
authors: Joaquín
authors: J
authors: Portilla Sogorb
authors: Alex
authors: A
authors: Rovira Cañellas
authors: M Jesús
authors: MJ
authors: Téllez Molina
authors: Juan Manuel
authors: JM
authors: Tiraboschi
authors: Esperanza
authors: E
authors: Vergara Moragues
authors: José Ramón
authors: JR
authors: Arribas López
authors: Miguel Ángel
authors: MÁ
authors: Goenaga Sánchez
authors: Fernando Lozano
authors: FL
authors: de León-Naranjo
authors: Esteban
authors: E
authors: Martínez Chamorro
authors: Rosa
authors: R
authors: Polo Rodríguez
authors: José A
authors: JA
authors: Muñoz-Moreno
authors: Daniel
authors: D
authors: Podzamczer
mesh_terms: D015526:AIDS Dementia Complex / Q000175:diagnosis* / Q000628:therapy*; D000465:Algorithms; D006801:Humans
keywords: Antiretroviral treatment; Human immunodeficiency virus; Neurocognitive disorders; Trastornos neurocognitivos; Tratamiento antirretroviral; Virus de la inmunodeficiencia humana