title: Hepatocellular carcinoma in HIV-infected women: two case reports.
abstract: With the widespread availability of highly active antiretroviral therapy (HAART), and increased life expectancy among HIV-infected individuals, liver-related mortality has emerged as the leading cause of non-AIDS-related death. The incidence of hepatocellular carcinoma (HCC), a sequela of chronic liver disease, is rising among HIV-infected individuals. While women are increasingly and disproportionately affected by HIV, little is known about HCC in HIV-infected women given HCC's predilection for men. In 2007, 2 out of 398 HIV-infected women seen at a Rhode Island HIV clinic were diagnosed with HCC. Of 351 HIV-infected individuals with HCC described in the published literature, 12 (3.4%) were women. These 2 cases add to the existing literature on this topic.
authors: Division of Infectious Diseases, Miriam Hospital, Providence, RI, USA.
authors: Michelle L
authors: ML
authors: Westbrook
authors: Shikha
authors: S
authors: Garg
authors: Stacey
authors: S
authors: Chapman
authors: Susan
authors: S
authors: Cu-Uvin
authors: Karen T
authors: KT
authors: Tashima
authors: Lynn E
authors: LE
authors: Taylor
mesh_terms: D000328:Adult; D023241:Antiretroviral Therapy, Highly Active; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D015897:Comorbidity; D017809:Fatal Outcome; D005260:Female; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008875:Middle Aged; D012367:RNA, Viral / Q000097:blood; D012189:Retrospective Studies; D012237:Rhode Island / Q000453:epidemiology; D019562:Viral Load; D016387:Women's Health
chemical_list: D012367:RNA, Viral
keywords: HIV; Hepatocellular Carcinoma; Women