title: The B cell helper side of neutrophils.
abstract: Neutrophils use opsonizing antibodies to enhance the clearance of intruding microbes. Recent studies indicate that splenic neutrophils also induce antibody production by providing helper signals to B cells lodged in the MZ of the spleen. Here, we discuss the B cell helper function of neutrophils in the context of growing evidence indicating that neutrophils function as sophisticated regulators of innate and adaptive immune responses.
authors: 1.Av. Dr. Aiguader 88, 08003 Barcelona, Spain. acerutti@imim.es; Twitter: http://www.imim.es/programesrecerca/inflamacio/en_bcellbiology.html or http://www.icrea.cat/Web/ScientificForm.aspx?key=452.
authors: Andrea
authors: A
authors: Cerutti
authors: Irene
authors: I
authors: Puga
authors: Giuliana
authors: G
authors: Magri
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000166:cytology* / Q000276:immunology*; D006801:Humans; D007155:Immunologic Factors / Q000378:metabolism; D018448:Models, Immunological; D009504:Neutrophils / Q000166:cytology* / Q000276:immunology*
chemical_list: D007155:Immunologic Factors
keywords: antibody production; granulocytes; innate immunity
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