title: Teaching NeuroImages: hemorrhagic cavernoma with secondary development of hypertrophic olivary degeneration.
abstract: Hypertrophic olivary degeneration (HOD) is secondary degeneration of the inferior olivary nucleus (ION) due to a primary lesion in the dento-rubro-olivary pathway. This pathway is known as the Guillain and Mollert triangle, containing the dentate nucleus and the contralateral red and inferior olivary nuclei (figure e-1 on the Neurology® Web site at www.neurology.org). The commonest presenting symptom is palatal myoclonus occurring 8-12 months after the primary insult. MRI of the ION initially has normal results (figure 1). Three phases of HOD exist on MRI: hyperintense signal change without hypertrophy, hyperintense signal change with hypertrophy (figure 2), and regression of hypertrophy with persistent hyperintense signal.(1.)
authors: Department of Neuroradiology, Beaumont Hospital, Dublin, Ireland. icrosbie81@gmail.com
authors: Ian
authors: I
authors: Crosbie
authors: Stephen
authors: S
authors: McNally
authors: Paul
authors: P
authors: Brennan
authors: Seamus
authors: S
authors: Looby
mesh_terms: D002543:Cerebral Hemorrhage / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D005500:Follow-Up Studies; D020786:Hemangioma, Cavernous, Central Nervous System / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D006984:Hypertrophy; D009410:Nerve Degeneration / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D009847:Olivary Nucleus / Q000473:pathology*