title: [Assessment of the impact of the use single-dose medications in 2 primary care centres].
abstract: OBJECTIVE
  To evaluate the economical impact of using medications packaged in a single dose non-reusable container (Onedose(®)), compared to prescribing preparations in the usual multidose containers.
  
  
  METHODS
  We performed a cost-minimization analysis from a prescribing center's perspective. The observational study design is retrospective and analyzes 23 products in prescriptions made between January and April 2012.
  
  
  METHODS
  Two Spanish Primary Care Centers located in the province of Barcelona. The first covered an urban area with a population of 24.500 people, and the second a semi-urban area with 10.000 people.
  
  
  METHODS
  Each examined product was measured between January and April 2012 and extrapolated annually, based on the defined substitution scenarios results of total Euro savings in non-prescribed doses and price differences.
  
  
  RESULTS
  The Savings related to the substitution of the prescribed packaging presentations with Onedose(®) were 45.000 Euros (24%) in the months of analysis and 133.000 Euros annually, avoiding the use of 212.000 doses (14%) in the period analyzed and 669.000 doses annually.
  
  
  CONCLUSIONS
  The use of single dose non-reusable container packaging (Onedose(®)) in the analyzed health centers reduced prescription-related expenses without increasing dispensing costs, thus reducing the household stock of those medicines which are not objectively suitable to be used without a previous diagnosis.
authors: Unidad de Farmacia Clínica y Farmacoterapia, Departamento de Farmacia y Tecnología Farmacéutica, Facultad de Farmacia, Universidad de Barcelona, Barcelona, España. Electronic address: lsegu@consorci.org.
authors: Jose Luis
authors: JL
authors: Segú Tolsà
authors: Ana
authors: A
authors: Rubio Dalmau
authors: Sonia
authors: S
authors: Pérez López
authors: Jose Luis
authors: JL
authors: Fernández Roure
authors: Josep
authors: J
authors: Serrat Torres
authors: Pilar
authors: P
authors: Modamio Charles
authors: Eduardo
authors: E
authors: Mariño Hernández
mesh_terms: D003365:Costs and Cost Analysis; D004338:Drug Combinations; D004359:Drug Therapy, Combination / Q000191:economics*; D006801:Humans; D011320:Primary Health Care; D012189:Retrospective Studies
chemical_list: D004338:Drug Combinations
keywords: Dosis unitaria; Efficiency; Eficiencia; Prescripción; Prescription; Single-dose
references: Gac Sanit. 2007 Jan-Feb;21(1):18-23; discussion 23-4
references: 17306181
references: Pharm World Sci. 2008 Jun;30(3):272-7
references: 18008178
references: Med Clin (Barc). 1982 Jul 1-31;79(3):118-21
references: 7109767
references: Aten Primaria. 1994 Mar 31;13(5):242-6
references: 7654922