title: Breakthrough disseminated cryptococcosis during micafungin therapy.
abstract: Echinocandins are not active against basidiomycetous yeasts, such as Cryptococcus neoformans, Trichosporon, and Rhodotorula species, and zygomycosis. We present a patient with renal failure and candidemia, who developed a breakthrough fungal infection with cryptococcemia and cryptococcuria while receiving micafungin therapy.
authors: Division of Infectious Disease, Department of Internal Medicine, Wan Fang Medical Center, Taipei Medical University, Taipei, Taiwan.
authors: Wen-Sen
authors: WS
authors: Lee
authors: Division of Infectious Disease, Department of Internal Medicine, Wan Fang Medical Center, Taipei Medical University, Taipei, Taiwan.
authors: Tai-Chin
authors: TC
authors: Hsieh
authors: Division of Infectious Disease, Department of Internal Medicine, Wan Fang Medical Center, Taipei Medical University, Taipei, Taiwan.
authors: Tsong-Yih
authors: TY
authors: Ou
authors: Division of Infectious Disease, Department of Internal Medicine, Wan Fang Medical Center, Taipei Medical University, Taipei, Taiwan.
authors: Sing-On
authors: SO
authors: Teng
authors: Division of Infectious Disease, Department of Internal Medicine, Wan Fang Medical Center, Taipei Medical University, Taipei, Taiwan.
authors: Fu-Lun
authors: FL
authors: Chen
authors: Division of Infectious Disease, Department of Internal Medicine, Taipei Veterans General Hospital, National Yang-Ming University of Medicine, Taipei, Taiwan. Electronic address: 89425@wanfang.gov.tw.
authors: Fu-Der
authors: FD
authors: Wang
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use*; D002177:Candidiasis / Q000150:complications; D003453:Cryptococcosis / Q000150:complications* / Q000188:drug therapy*; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D054714:Echinocandins / Q000627:therapeutic use*; D016469:Fungemia / Q000175:diagnosis* / Q000473:pathology*; D006801:Humans; D055666:Lipopeptides / Q000627:therapeutic use*; D008297:Male; D000077551:Micafungin; D051437:Renal Insufficiency / Q000150:complications
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D000077551:Micafungin
keywords: Breakthrough fungal infection; Cryptococcosis; Micafungin