title: Dual-purpose PEG scaffolds for the preparation of soft and biofunctional hydrogels: the convergence between CuAAC and thiol-ene reactions.
abstract: Orthogonally functionalized PEGs displaying alkenes and azides have been prepared and their dual-purpose scaffolding potential was exploited via click chemistry for controlled insertion of biorelevant moieties as well as facile fabrication of soft, non-toxic and degradable hydrogels.
authors: KTH Royal Institute of Technology, Department of Fibre and Polymer Technology, Teknikringen 56-68, SE-100 44 Stockholm, Sweden.
authors: Kim
authors: K
authors: Öberg
authors: Yvonne
authors: Y
authors: Hed
authors: Isabella Joelsson
authors: IJ
authors: Rahmn
authors: Jonathan
authors: J
authors: Kelly
authors: Peter
authors: P
authors: Löwenhielm
authors: Michael
authors: M
authors: Malkoch
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D001386:Azides / Q000737:chemistry*; D002384:Catalysis; D002470:Cell Survival; D003300:Copper / Q000737:chemistry*; D003500:Cyclization; D005347:Fibroblasts / Q000166:cytology; D006801:Humans; D020100:Hydrogels / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D011092:Polyethylene Glycols / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D000480:Alkynes; D001386:Azides; D020100:Hydrogels; D013438:Sulfhydryl Compounds; D011092:Polyethylene Glycols; D003300:Copper