title: Is daily headache related to asthma? Results from a population-based survey.
abstract: OBJECTIVE
  Despite the high worldwide prevalence of asthma and headache, little is known about the association between these conditions. The objective of our study was to evaluate the association between asthma and daily headache in a representative sample of the general population of South Korea.
  
  
  METHODS
  We retrospectively analyzed 7984 individuals included in the Second Korean National Health and Nutrition Examination Survey (KNHANES II), a prospectively administered survey performed in 2001 by a government organization within the Ministry of Health and Welfare. After adjustment of risk factors for daily headache, multivariate logistic regression analysis was performed to evaluate the association between asthma and daily headache.
  
  
  RESULTS
  Of 7984 individuals, 69 (0.9%) had daily headache and 429 (5.4%) had asthma symptoms. Daily headache was significantly more prevalent in subjects with asthma symptoms (14/429, 3.3%) than in those without (55/7555, 0.7%; p < 0.001). Of the 4833 nonsmokers, 46 (1.0%) had daily headache and 287 (5.9%) had asthma symptoms, with daily headache being significantly more prevalent in subjects with asthma symptoms (11/231, 4.8%) than in those without (35/4602, 0.8%; p < 0.001). Multivariate logistic regression showed that the odds ratios for daily headache were 2.3 (95% CI: 1.21-4.33, p = 0.01) in all individuals with asthma symptoms and 3.4 (95% CI: 1.65-7.12, p = 0.001) in nonsmokers with asthma symptoms.
  
  
  CONCLUSIONS
  Individuals with asthma symptoms are at higher risk of daily headache than those without the symptoms, suggesting a link between these conditions.
authors: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan.
authors: Young Seok
authors: YS
authors: Lee
authors: Gi Dong
authors: GD
authors: Lee
authors: Jae Seung
authors: JS
authors: Lee
authors: Chin Kook
authors: CK
authors: Rhee
authors: Tae Sun
authors: TS
authors: Shim
authors: Woo Sung
authors: WS
authors: Kim
authors: Sang-Do
authors: SD
authors: Lee
authors: Yeon-Mok
authors: YM
authors: Oh
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000150:complications / Q000453:epidemiology*; D015331:Cohort Studies; D005260:Female; D006261:Headache / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D055815:Young Adult