title: Dyslipidemia is associated with tunneled-cuffed catheter-related central venous thrombosis in hemodialysis patients: a retrospective, multicenter study.
abstract: The aim of this study was to explore the risk factors of tunneled-cuffed catheter (TCC)-related central venous thrombosis (CVT) for the maintenance of hemodialysis patients. In this study, 285 patients on maintenance hemodialysis were enrolled who had received their first TCC in the right jugular vein. Patients were divided into CVT and control groups according to the diagnosis of TCC-related CVT 6 months after catheterization. Patients with CVT had a higher prevalence of dyslipidemia (50.74 vs. 26.85%, respectively) and low protein store compared with the control group. After adjusting for confounders, serum triglycerides (OR: 3.632; 95% CI: 2.105-6.267), non-HDL cholesterol (OR: 1.463; 95% CI:1.067-2.007), and low-density lipoprotein/high-density lipoprotein (LDL/HDL) cholesterol ratio (OR: 2.904; 95% CI: 1.797-4.692) were positively correlated with TCC-related CVT, while serum HDL cholesterol (OR: 0.097; 95% CI: 0.037-0.257) and serum albumin (OR: 0.922; 95% CI: 0.864-0.985) were negatively correlated. Dyslipidemia and low serum albumin levels were significantly associated with TCC-related CVT in hemodialysis patients.
authors: Division of Nephrology, West China Hospital, West China Medical School, Sichuan University, Chengdu, China.
authors: Yuan
authors: Y
authors: Cheng
authors: Tianlei
authors: T
authors: Cui
authors: Ping
authors: P
authors: Fu
authors: Fang
authors: F
authors: Liu
authors: Li
authors: L
authors: Zhou
mesh_terms: D000368:Aged; D016022:Case-Control Studies; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D002408:Catheters, Indwelling / Q000009:adverse effects; D050171:Dyslipidemias / Q000097:blood* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012307:Risk Factors; D012709:Serum Albumin / Q000032:analysis; D020246:Venous Thrombosis / Q000150:complications*
chemical_list: D012709:Serum Albumin
keywords: Central venous thrombosis; Dyslipidemia; Hemodialysis; Low serum albumin; Tunneled-cuffed catheters