title: Association between ambient temperature and acute myocardial infarction hospitalisations in Gothenburg, Sweden: 1985-2010.
abstract: Cardiovascular disease (CVD) is the number one cause of death globally and evidence is steadily increasing on the role of non-traditional risk factors such as meteorology and air pollution. Nevertheless, many research gaps remain, such as the association between these non-traditional risk factors and subtypes of CVD, such as acute myocardial infarction (AMI). The objective of this study was to investigate the association between daily ambient temperature and AMI hospitalisations using a case-crossover design in Gothenburg, Sweden (1985-2010). A secondary analysis was also performed for out-of-hospital ischemic heart disease (IHD) deaths. Susceptible groups by age and sex were explored. The entire year as well as the warm (April-September) and cold periods (October-March) were considered. In total 28,215 AMI hospitalisations (of 22,475 people) and 21,082 out-of-hospital IHD deaths occurred during the 26-year study period. A linear exposure-response corresponding to a 3% and 7% decrease in AMI hospitalisations was observed for an inter-quartile range (IQR) increase in the 2-day cumulative average of temperature during the entire year (11°C) and the warm period (6°C), respectively, with and without adjustment for PM₁₀, NO₂, NOx or O₃. No heat waves occurred during the warm period. No evidence of an association in the cold period nor any association between temperature and IHD deaths in the entire year, warm or cold periods--with and without adjusting for PM₁₀, NO₂, NOx or O₃ was found. No susceptible groups, based on age or sex, were identified either. The inverse association between temperature and AMI hospitalisations (entire year and warm period) in Gothenburg is in accordance with the majority of the few other studies that investigated this subtype of CVD.
authors: Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital and University of Gothenburg, Gothenborg, Sweden. gerd.sallsten@amm.gu.se
authors: Janine
authors: J
authors: Wichmann
authors: Annika
authors: A
authors: Rosengren
authors: Karin
authors: K
authors: Sjöberg
authors: Lars
authors: L
authors: Barregard
authors: Gerd
authors: G
authors: Sallsten
mesh_terms: D000328:Adult; D000367:Age Factors; D000393:Air Pollutants / Q000032:analysis; D000397:Air Pollution; D005260:Female; D049673:History, 20th Century; D049674:History, 21st Century; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology* / Q000209:etiology* / Q000266:history; D010343:Patient Admission; D012307:Risk Factors; D012621:Seasons; D012737:Sex Factors; D013548:Sweden / Q000453:epidemiology; D013696:Temperature; D055815:Young Adult
chemical_list: D000393:Air Pollutants
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