title: [A case of gallbladder metastasis from a malignant perivascular epithelioid cell tumor of the bladder].
abstract: The perivascular epithelioid cell family of tumors (PEComas) includes common lesions such as angiomyolipomas, lymphangioleiomyomas, and clear cell "sugar" tumors of the lung. Less frequently, PEComas arise in various other locations throughout the body, including the soft tissue, bone, and the visceral organs. We report the case of a 64-year-old man who underwent total cystectomy because of a primary malignant PEComa of the bladder in August 2010. The patient was treated with the mammalian target of rapamycin inhibitor for lung and bone metastasis from April 2011 and showed stable disease. Computed tomography showed a growing mass in the neck of the gallbladder 5 months later, which was suspected to be gallbladder cancer. Cholecystectomy and lymphadenectomy was performed in February 2012, and histopathological examination indicated gallbladder metastasis from the primary malignant PEComa of the bladder. This is, to our knowledge, the first report of malignant PEComa metastasis to the gallbladder.
authors: Division of Gastroenterological Surgery, Hyogo Cancer Center, Japan. sendou@hp.pref.hyogo.jp
authors: Hiroyoshi
authors: H
authors: Sendo
authors: Hitoshi
authors: H
authors: Harada
authors: Hiroshi
authors: H
authors: Hasegawa
authors: Takashi
authors: T
authors: Yasuda
authors: Tadayuki
authors: T
authors: Ohara
authors: Taro
authors: T
authors: Oshikiri
authors: Kenichi
authors: K
authors: Tanaka
authors: Yasuhiro
authors: Y
authors: Fujino
authors: Masahiro
authors: M
authors: Tominaga
mesh_terms: D005706:Gallbladder Neoplasms / Q000473:pathology / Q000556:secondary*; D006801:Humans; D008297:Male; D008875:Middle Aged; D054973:Perivascular Epithelioid Cell Neoplasms / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000473:pathology*