title: Enantioselective total synthesis of (+)-brazilin, (-)-brazilein and (+)-brazilide A.
abstract: An enantioselective strategy for the synthesis of (+)-brazilin, (-)-brazilein and (+)-brazilide A has been developed. A Lewis acid mediated lactonization established the novel fused bis-lactone core of brazilide A and finalized the first total synthesis of (+)-brazilide A.
authors: Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China.
authors: Xuequan
authors: X
authors: Wang
authors: Hongbin
authors: H
authors: Zhang
authors: Xiaodong
authors: X
authors: Yang
authors: Jingfeng
authors: J
authors: Zhao
authors: Chengxue
authors: C
authors: Pan
mesh_terms: D001578:Benzopyrans / Q000737:chemistry*; D029911:Caesalpinia; D007192:Indenes / Q000737:chemistry*; D007783:Lactones / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D001578:Benzopyrans; D007192:Indenes; D007783:Lactones; C050295:brazilein; C044362:brazilin