title: The effect of anti-reflux treatment on subjective voice measurements of patients with laryngopharyngeal reflux.
abstract: OBJECTIVE
  To assess the impact of anti-reflux treatment and speech therapy on subjective voice measurements of patients with laryngopharyngeal reflux.
  
  
  METHODS
  This paper reports a prospective study of patients seen in a voice clinic over a three-year period who were being treated for laryngopharyngeal reflux. Patients were assessed at presentation using the reflux symptom index and voice symptom scale, and were reassessed at three months and six months post-treatment. Treatment entailed twice daily proton pump inhibitor therapy and speech therapy.
  
  
  RESULTS
  The study comprised 74 patients. The reflux symptom index and voice symptom scale scores significantly improved following treatment at both three and six months. There was a correlation between improved reflux symptom index scores and improved voice symptom scale scores.
  
  
  CONCLUSIONS
  Treatment of laryngopharyngeal reflux with twice daily proton pump inhibitors and speech therapy resulted in improved subjective voice measurements for patients.
authors: Department of ENT, City Hospital, Birmingham, UK. tbeech@nhs.net
authors: T J
authors: TJ
authors: Beech
authors: G
authors: G
authors: Campbell
authors: A L
authors: AL
authors: McDermott
authors: A J
authors: AJ
authors: Batch
mesh_terms: D006801:Humans; D057045:Laryngopharyngeal Reflux / Q000188:drug therapy*; D011446:Prospective Studies; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*; D012720:Severity of Illness Index; D013070:Speech Therapy; D016896:Treatment Outcome; D014831:Voice / Q000187:drug effects*; D014832:Voice Disorders / Q000209:etiology / Q000628:therapy
chemical_list: D054328:Proton Pump Inhibitors