title: [Destrution of ossicular chain and it's impact on hearing of patients with tympanosclerosis].
abstract: OBJECTIVE
  To study the destruction ossicular chain's impact on hearing of patients with tympanosclerosis.
  
  
  METHODS
  A retrospective review was conducted in 115 patients with tympanosclerosis, all patients were divided into 3 groups, including normal ossicular chain structure (A group), fixed ossicular chain(B group), and interrupted ossicular chain (C group). The audiological feature of the patients were compared between the 3 group.
  
  
  RESULTS
  Difference were significant for PTA, 0.5, 1.0, 2.0, 4.0 kHz air conduction threshold between 3 group (P < 0.01). Difference were significant for air bone gap (ABG) between A, B groups and C group (P < 0.01), there was no difference for ABG between A and B group (P > 0.01). Difference were significant for air conduction threshold between 0.5, 1.0 kHz and 2, 4 kHz in A, B groups (P < 0.01), but there was no significant for same data in C group (P > 0.01). Difference were significant for average bone conduction, 1, 2, 4 kHz bone-conduction threshold between A group and B, C group (P < 0.01). The rate of Carhart notch was low and had no difference between 3 group (P > 0.01).
  
  
  CONCLUSIONS
  The ossicular chain was fixed in patients who's PTA > or = (54.31 +/-13.19) dB HL and was interrupted who's PTA > or = (63.90 +/- 20.29) dB HL or ABG > or = (33.23 +/- 8.49) dB HL. The rising shaped curve in air-conduction audiograph may indicate the ossicular chain was fixed,and the smooth shape curve may indicate the ossicular chain was interrupted.
authors: Department of Otolaryngology, West China Hospital, Sichuan University, Chengdu 610041, China.
authors: Jing
authors: J
authors: Chen
authors: Yan
authors: Y
authors: Zheng
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001301:Audiometry, Pure-Tone; D001844:Bone Conduction; D002648:Child; D004429:Ear Ossicles / Q000473:pathology*; D005260:Female; D006309:Hearing; D006801:Humans; D008297:Male; D008875:Middle Aged; D063371:Myringosclerosis / Q000473:pathology* / Q000503:physiopathology*; D012189:Retrospective Studies; D055815:Young Adult