title: Outcome of ischemic foot ulcer in diabetic patients who had no invasive vascular intervention.
abstract: OBJECTIVE
  There is limited information regarding outcome in patients not available for revascularisation. Our aim was to identify factors related to ulcer healing in diabetic patients with severe peripheral arterial disease who were not available for revascularisation.
  
  
  METHODS
  Diabetic patients with a foot ulcer, consecutively presenting at a multidisciplinary foot centre with systolic toe pressure <45 mmHg or an ankle pressure <80 mmHg were prospectively included. Patients who received revascularisation were excluded. All patients had continuous follow-up until healing or death.
  
  
  RESULTS
  Out of 602 patients (median age: 76 years) included in this study, 50% healed either primarily (76%) or with a minor amputation (24%). Seventeen percent of patients healed after major amputation and 33% died unhealed. By regression analysis, rest pain, impaired renal function, ischemic heart disease, cerebral vascular disease, extent of tissue destruction, and ankle pressure >50 mmHg affected the outcome of the ulcers.
  
  
  CONCLUSIONS
  Diabetic patients with ischemic foot ulcers not available for revascularisations are not excluded from healing without major amputation. Factors strongly related to outcome were co-morbidity, severity of peripheral arterial disease, and extent of tissue destruction. Our findings reinforce the need for a classification system considering these factors at decision-making for vascular intervention.
authors: Department of Endocrinology, Skåne University Hospital, Malmö, Sweden. targ.elgzyri@med.lu.se
authors: T
authors: T
authors: Elgzyri
authors: J
authors: J
authors: Larsson
authors: J
authors: J
authors: Thörne
authors: K-F
authors: KF
authors: Eriksson
authors: J
authors: J
authors: Apelqvist
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017719:Diabetic Foot / Q000150:complications* / Q000601:surgery*; D005260:Female; D005528:Foot / Q000098:blood supply*; D006801:Humans; D007511:Ischemia / Q000150:complications*; D008297:Male; D008875:Middle Aged; D058729:Peripheral Arterial Disease / Q000150:complications*; D011446:Prospective Studies; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures