title: Overweight and Obesity, Lipid Profile and Atherogenic Indices among Civil Servants in Abakaliki, South Eastern Nigeria.
abstract: BACKGROUND
  The association between dyslipidaemia, obesity and hypertension is well established, and all have been found to be risk factors for cardiovascular disease (CVD).
  
  
  OBJECTIVE
  To determine the prevalence of overweight and obesity, plasma lipid profile and atherogenic indices as markers for CVD among civil servants.
  
  
  METHODS
  Two hundred and five (205) apparently healthy civil servants (106, 51.7% males) aged 21-60 years, mean and standard deviation (SD) 40.9 (11.3) years, enrolled between February and April 2008 were assessed for their plasma lipid profile and anthropometrics (body weight and height) using standard methods and techniques.
  
  
  RESULTS
  Prevalent rates of overweight and obesity were 34.2% (70/205) and 6.8% (14/205), respectively, with more men affected than women. Abnormal lipids observed were: Elevated total cholesterol 37.1% (76/205), low-density lipoprotein-cholesterol (LDL-C) 37.1% (76/205), triglyceride 6.8% (14/205), reduced high-density lipoprotein-cholesterol (HDL-C) 8.8% (18/205) and elevated Atherogenic Index 10.7% (22/205) and Coronary Risk Index 9.8% (20/205), with the older age groups and higher Body Mass Index (BMI) groups being the most affected. Male subjects were found to have more favorable plasma lipid profile (lower LDL-C and higher HDL-C) than the females. Plasma lipids were positively correlated with BMI and artherogenic indices, except for HDL-C, which was negatively correlated with artherogenic indices and LDL-C but positively correlated with BMI.
  
  
  CONCLUSIONS
  The findings show that civil servants in Abakaliki, particularly the females, those with higher BMI and advanced in age, exhibited unfavorable plasma lipids and social habits with a low level of physical activity, which may predispose them to CVD. In addition to epidemiological study of the general population, there is a need for education on healthier lifestyles such as good nutrition, weight reduction, smoking and alcohol cessation, greater physical activity and regular medical check-up.
authors: Department of Chemical Pathology, Faculty of Clinical Medicine, Ebonyi State University, P.M.B 053 Abakaliki, Nigeria.
authors: Ei
authors: E
authors: Ugwuja
authors: Nc
authors: N
authors: Ogbonna
authors: An
authors: A
authors: Nwibo
authors: Ia
authors: Ia
authors: Onimawo
keywords: Cardiovascular disease; Dyslipidaemia; Obesity; Overweight
references: Growth. 1983 Autumn;47(3):263-71
references: 6605900
references: Niger J Med. 2006 Apr-Jun;15(2):137-40
references: 16805169
references: Clin Chem. 1973 Dec;19(12):1350-6
references: 4757363
references: Acta Trop. 2001 Jun 22;79(3):231-9
references: 11412807
references: J Hum Hypertens. 1999 Jan;13(1):23-7
references: 9928748
references: Southeast Asian J Trop Med Public Health. 2008 Sep;39(5):932-41
references: 19058592
references: Clin Chim Acta. 1984 Jun 27;140(1):77-83
references: 6744629
references: Am J Clin Nutr. 2006 May;83(5):1025-31; quiz 1205
references: 16685042
references: Niger J Clin Pract. 2008 Dec;11(4):330-5
references: 19320405
references: Scand J Clin Lab Invest Suppl. 2005;240:14-7
references: 16112955
references: Lancet. 2006 May 27;367(9524):1747-57
references: 16731270
references: J Am Coll Surg. 2008 Dec;207(6):928-34
references: 19183541
references: Public Health Nutr. 2008 Mar;11(3):246-51
references: 17625028
references: N Engl J Med. 2002 Nov 7;347(19):1483-92
references: 12421890
references: Public Health Nutr. 2002 Feb;5(1A):231-7
references: 12027289
references: Int J Obes Relat Metab Disord. 2001 Nov;25(11):1722-9
references: 11753596
references: Circulation. 2002 Dec 17;106(25):3143-421
references: 12485966
references: Asia Pac J Public Health. 2011 Jul;23(4):507-17
references: 19825841
references: Med J Malaysia. 1997 Dec;52(4):348-66
references: 10968112
references: Public Health. 2009 May;123(5):365-70
references: 19362725
references: Obes Res. 2000 Dec;8(9):605-19
references: 11225709
references: Obes Rev. 2007 Jan;8(1):3-10
references: 17212790
references: J Lipid Res. 1970 Nov;11(6):583-95
references: 4100998