title: Apparent diffusion coefficient values predict outcomes of abusive head trauma.
abstract: OBJECTIVE
  To evaluate the apparent diffusion coefficient (ADC) values for predicting the long-term neurodevelopmental outcomes of patients with abusive head trauma (AHT).
  
  
  METHODS
  Apparent diffusion coefficient maps were retrospectively reviewed for 14 patients who presented with AHT at a mean age of 6.7 months (range 1-18 months), and the clinical outcomes of the survivors were based on the Glasgow Outcome Score.
  
  
  RESULTS
  One of 14 infants died, and two were severely disabled. One had mild impairment and four had moderate disability. In the 4 days after admission, the ADC values in all brain regions were strongly associated with a poor neurodevelopmental outcome (p < 0.05): basal ganglia, thalamus, brain stem, corpus callosum, frontal white matter, central white matter, parietal white matter, frontal grey matter, parietal grey matter, cerebellar vermis, cerebellar cortex and mean total brain.
  
  
  CONCLUSIONS
  Apparent diffusion coefficient values during the acute phase of AHT were significantly associated with poor long-term neurodevelopmental outcomes.
authors: Department of General Medicine, Kanagawa Children's Medical Center, Kanagawa, Japan. ktanoue@kcmc.jp
authors: Koji
authors: K
authors: Tanoue
authors: Noriko
authors: N
authors: Aida
authors: Kiyoshi
authors: K
authors: Matsui
mesh_terms: D002493:Central Nervous System Diseases / Q000175:diagnosis* / Q000209:etiology; D002649:Child Abuse; D015331:Cohort Studies; D006259:Craniocerebral Trauma / Q000175:diagnosis* / Q000209:etiology; D002658:Developmental Disabilities / Q000175:diagnosis / Q000209:etiology; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment; D038642:Shaken Baby Syndrome / Q000175:diagnosis* / Q000401:mortality; D015996:Survival Rate