title: Sympathetic skin response in patients with primary premature ejaculation.
abstract: To evaluate the possible role of the autonomic (sympathetic) nervous system function among the patients with primary premature ejaculation (PPE) and determine whether there is an etiological basis for this condition. We performed sympathetic skin response located in the penis (PSSR) in 52 patients with PPE and 46 normally potent men. The latencies and amplitudes of PSSR were measured. The PSSR waveforms were classified into P type and N type according to the waveform characteristics. The waveform distribution in the PPE patients was not statistically different from that in the control group (P=0.609). Mean latency of the PSSR was significantly shorter in the patients than that in the normally potent men (P<0.001). Mean amplitude of the PSSR was significantly greater in patients than that in the normal men (P<0.001). Patients with PPE have hyperactivity of the sympathetic nervous system, which may be another factor involved in the pathological mechanisms of PPE, and the PSSR is an objective test to evaluate patients with PPE.
authors: Department of Andrology, Nanjing Drum Tower Hospital, Nanjing Medical University, Nanjing, China.
authors: J-D
authors: JD
authors: Xia
authors: Department of Andrology, Nanjing Drum Tower Hospital, Nanjing Medical University, Nanjing, China.
authors: Y-F
authors: YF
authors: Han
authors: Department of Andrology, The Affiliated Drum Tower Hospital of Nanjing University, School of Medicine, Nanjing, China.
authors: L-H
authors: LH
authors: Zhou
authors: Department of Andrology, The Affiliated Drum Tower Hospital of Nanjing University, School of Medicine, Nanjing, China.
authors: Z-P
authors: ZP
authors: Xu
authors: 1] Department of Andrology, Nanjing Drum Tower Hospital, Nanjing Medical University, Nanjing, China [2] Department of Andrology, The Affiliated Drum Tower Hospital of Nanjing University, School of Medicine, Nanjing, China.
authors: Y
authors: Y
authors: Chen
authors: 1] Department of Andrology, Nanjing Drum Tower Hospital, Nanjing Medical University, Nanjing, China [2] Department of Andrology, The Affiliated Drum Tower Hospital of Nanjing University, School of Medicine, Nanjing, China.
authors: Y-T
authors: YT
authors: Dai
mesh_terms: D000328:Adult; D005712:Galvanic Skin Response / Q000502:physiology*; D006801:Humans; D008297:Male; D010413:Penis / Q000294:innervation / Q000503:physiopathology*; D061686:Premature Ejaculation / Q000503:physiopathology*; D012867:Skin / Q000294:innervation; D013564:Sympathetic Nervous System / Q000503:physiopathology*
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