title: Solid variant of keratocystic odontogenic tumor of the mandible: report of a case with a clear cell component and review of the literature.
abstract: This is a case report on a solid variant of keratocystic odontogenic tumor arising in the mandible, which aggressively infiltrated into the cancelous spaces and involved the periosteal connective tissue of the mandible. The patient was a 57-year-old woman with an ill-defined radiolucent lesion having a moth-eaten pattern in the left molar region of the mandible. Computed tomography scans revealed that the tumor penetrated the buccal cortical plate of the mandible. Histologically, the lesion was characterized by multicystic spaces lined with a thin layer of keratinizing squamous epithelium, which contained basal cells with palisaded hyperchromatic nuclei. Lumina were filled with concentric layers of parakeratin. An additional feature was the appearance of a conspicuous clear cell component showing intraluminal papillary proliferation or forming small cord-like nests in the fibrous stroma. The patient underwent segmental mandibulectomy followed by reconstruction using a titanium plate. A 20-year follow-up revealed no recurrence of the tumor.
authors: Professor and Head, Department of Dentistry and Oral-Maxillo-Facial Surgery, Faculty of Medicine, Oita University, Oita, Japan. Electronic address: kekawano@oita-u.ac.jp.
authors: Kenji
authors: K
authors: Kawano
authors: Kazuhiko
authors: K
authors: Okamura
authors: Kenji
authors: K
authors: Kashima
authors: Kou
authors: K
authors: Matsuo
authors: Yoshihiro
authors: Y
authors: Takahashi
authors: Noriaki
authors: N
authors: Yamamoto
authors: Tatsuyuki
authors: T
authors: Kono
authors: Kazuhiro
authors: K
authors: Kawamura
mesh_terms: D005260:Female; D006801:Humans; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009808:Odontogenic Tumors / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011862:Radiography, Panoramic; D014057:Tomography, X-Ray Computed