title: Henoch Schonlein Purpura in children: clinical analysis of 120 cases.
abstract: BACKGROUND
  Henoch Schonlein Purpura (HSP) is a systemic vasculitic disease which is common in children. It is very important to understand the clinical features of this disease for doctors and nurses.
  
  
  OBJECTIVE
  To study the clinical characteristics of HSP in children.
  
  
  METHODS
  Collect the clinical data of the HSP children, and analyze the clinical characteristics of these HSP patients.
  
  
  RESULTS
  The ratio of M:F was 1.9:1. The mean age was 6.6 ± 1.6 years. The typical onset seasons were spring, winter and autumn. Infection and food allergy were the main etiological factors. The first symptom was skin purpura and these purpura mainly concentrated the lower extremities and buttocks. The dominant digestive clinical features were abdominal pains and vomiting. The knee joint and ankle joint were most frequently affected. The typical kidney symptoms were microscopic hematuria and albuminuria. An increased ESR was reported in 68 patients (56.7%). Serum C3 decreased in 13 cases (10.8%). ASO titer was higher in 57 children (47.5%).
  
  
  CONCLUSIONS
  There were gender, season and area differences for the HSP patients. The etiological factors were diverse. HSP patients could have various clinical symptoms and rare complications.
authors: Department of Pediatrics, Qilu Hospital, Shandong University, #107 West Wenhua Road, Jinan 250012, China.
authors: O
authors: O
authors: Chen
authors: X B
authors: XB
authors: Zhu
authors: P
authors: P
authors: Ren
authors: Y B
authors: YB
authors: Wang
authors: R P
authors: RP
authors: Sun
authors: D E
authors: DE
authors: Wei
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006417:Hematuria / Q000209:etiology / Q000652:urine; D006801:Humans; D011695:IgA Vasculitis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D015994:Incidence; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D012621:Seasons; D017678:Sex Distribution; D012867:Skin / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids
keywords: Children; Henoch Schonlein Purpura
references: Lancet. 1997 Oct 18;350(9085):1116-7
references: 9343495
references: Br Med J (Clin Res Ed). 1988 Jun 25;296(6639):1800
references: 3136851
references: Lancet. 2002 Oct 19;360(9341):1197-202
references: 12401245
references: Semin Arthritis Rheum. 1999 Jun;28(6):404-12
references: 10406408
references: Trop Geogr Med. 1990 Jan;42(1):52-7
references: 2260196
references: Arthritis Rheum. 1990 Aug;33(8):1114-21
references: 2202310
references: J Pediatr Surg. 1996 Jun;31(6):809-11
references: 8783109
references: J Rheumatol. 2004 Nov;31(11):2295-9
references: 15517648
references: Semin Arthritis Rheum. 2002 Dec;32(3):149-56
references: 12528079
references: Autoimmun Rev. 2008 Jan;7(3):179-84
references: 18190875
references: Medicine (Baltimore). 2001 Sep;80(5):279-90
references: 11552081
references: Eur J Pediatr. 2002 Apr;161(4):196-201
references: 12014385
references: Medicine (Baltimore). 1998 Nov;77(6):403-18
references: 9854604
references: Acta Paediatr Scand. 1988 Jan;77(1):125-31
references: 3369292
references: Rheumatology (Oxford). 2001 Mar;40(3):345-6
references: 11285387
references: Arch Dis Child. 1982 Apr;57(4):322-3
references: 7082050
references: Medicine (Baltimore). 1999 Nov;78(6):395-409
references: 10575422
references: Semin Arthritis Rheum. 2005 Dec;35(3):143-53
references: 16325655
references: Lupus. 1998;7(4):259-65
references: 9643315
references: Lancet. 2007 Mar 24;369(9566):976-8
references: 17382810
references: Eur J Pediatr. 1988 Feb;147(2):113-5
references: 3366130
references: Am J Dis Child. 1989 Jul;143(7):798-803
references: 2741850