title: Primary hyperparathyroidism presenting as a giant cell tumor of the jaws.
abstract: OBJECTIVE
  Giant cell tumors of the maxillofacial skeleton are uncommon, they are usually late manifestation of primary hyperparathyroidism. A series of five clinical cases in four women and one man presenting as the giant cell lesions in the maxilla and/or mandible are discussed.
  
  
  METHODS
  Biopsy of the lesions, biochemical and hormonal analyses, densitometry and parathyroid scintigraphy were carried out.
  
  
  RESULTS
  Biopsy of the lesions showed giant cell tumor of bone. The medical history and laboratory analyses showed primary hyperparathyroidism. Bone density loss was documented and scintigraphy revealed the presence of parathyroid adenomas in four cases. Surgical treatment of hyperparathyroidism, and in the second step - after 6-12 months - the subsequent excision of residual brown tumors in all cases was performed.
  
  
  CONCLUSIONS
  One should have in mind that osteolytic bone lesions may be due to metabolic disease of the bone. Accurate diagnosis enabling the proper treatment should be carried out, avoiding unnecessary harm to the patients.
authors: Department of Cranio-Maxillofacial Surgery, Wrocław Medical University, Poland.
authors: Wojciech
authors: W
authors: Pawlak
authors: Anna
authors: A
authors: Bohdanowicz-Pawlak
authors: Marek
authors: M
authors: Bolanowski
authors: Jadwiga
authors: J
authors: Szymczak
authors: Grazyna
authors: G
authors: Bednarek-Tupikowska
authors: Klaudiusz
authors: K
authors: Luczak
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods; D005260:Female; D005870:Giant Cell Tumors / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D007573:Jaw Neoplasms / Q000473:pathology* / Q000601:surgery; D008297:Male; D008441:Maxillary Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D010282:Parathyroid Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D016896:Treatment Outcome