title: Comparative genomics of Bifidobacterium animalis subsp. lactis reveals a strict monophyletic bifidobacterial taxon.
abstract: Strains of Bifidobacterium animalis subsp. lactis are extensively exploited by the food industry as health-promoting bacteria, although the genetic variability of members belonging to this taxon has so far not received much scientific attention. In this article, we describe the complete genetic makeup of the B. animalis subsp. lactis Bl12 genome and discuss the genetic relatedness of this strain with other sequenced strains belonging to this taxon. Moreover, a detailed comparative genomic analysis of B. animalis subsp. lactis genomes was performed, which revealed a closely related and isogenic nature of all currently available B. animalis subsp. lactis strains, thus strongly suggesting a closed pan-genome structure of this bacterial group.
authors: Laboratory of Probiogenomics, Department of Life Sciences, University of Parma, Parma, Italy.
authors: Christian
authors: C
authors: Milani
authors: Sabrina
authors: S
authors: Duranti
authors: Gabriele Andrea
authors: GA
authors: Lugli
authors: Francesca
authors: F
authors: Bottacini
authors: Francesco
authors: F
authors: Strati
authors: Stefania
authors: S
authors: Arioli
authors: Elena
authors: E
authors: Foroni
authors: Francesca
authors: F
authors: Turroni
authors: Douwe
authors: D
authors: van Sinderen
authors: Marco
authors: M
authors: Ventura
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D001644:Bifidobacterium / Q000145:classification* / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D016680:Genome, Bacterial; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D020543:Proteome; D017422:Sequence Analysis, DNA; D013752:Tetracycline / Q000494:pharmacology; D013753:Tetracycline Resistance
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D020543:Proteome; D013752:Tetracycline
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