title: Electrochemical cholesterol sensor based on carbon nanotube@molecularly imprinted polymer modified ceramic carbon electrode.
abstract: A monolithic molecular imprinting sensor based on ceramic carbon electrode (CCE) has been reported. The sensor can be renewed simply by smoothing. It was fabricated by thoroughly mixing multiwalled carbon nanotube@molecularly imprinted polymer (MWCNT@MIP), graphite powder, and silicon alkoxide, and then packing the resulting complex mixture of components firmly into the electrode cavity of a Teflon sleeve. The incorporated MWCNT@MIP in CCEs functioned as a recognition element for cholesterol determination. The MWCNT@MIP-CCEs were tested in the presence or absence of cholesterol by cyclic voltammetry and linear sweep voltammetry. The cholesterol sensor has excellent sensitivity with a linear range of 10-300nM and a detection limit of 1nM (S/N=3). The monolithic molecular imprinting sensor exhibits good stability, high sensitivity, and user-friendly reusability for cholesterol determination. This study shows that CCE is a promising matrix for MIP sensors.
authors: College of Chemistry and Chemical Engineering, Fujian Normal University, Fuzhou 350007, China. tongyuejin@yahoo.com.cn
authors: Yuejin
authors: Y
authors: Tong
authors: Haidong
authors: H
authors: Li
authors: Huaimin
authors: H
authors: Guan
authors: Jianming
authors: J
authors: Zhao
authors: Saadat
authors: S
authors: Majeed
authors: Saima
authors: S
authors: Anjum
authors: Feng
authors: F
authors: Liang
authors: Guobao
authors: G
authors: Xu
mesh_terms: D015374:Biosensing Techniques / Q000379:methods*; D002516:Ceramics / Q000737:chemistry; D002784:Cholesterol / Q000737:chemistry / Q000302:isolation & purification*; D055664:Electrochemical Techniques; D004566:Electrodes; D006046:Gold / Q000737:chemistry; D006108:Graphite / Q000737:chemistry; D006801:Humans; D057230:Limit of Detection; D054802:Molecular Imprinting; D037742:Nanotubes, Carbon / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry
chemical_list: D037742:Nanotubes, Carbon; D011108:Polymers; D006046:Gold; D006108:Graphite; D002784:Cholesterol