title: Newly identified synergy between clopidogrel and calcium-channel blockers for blood pressure regulation possibly involves CYP2C19 rs4244285.
authors: UMR INSERM U 1122, IGE-PCV "Interactions Gène-Environnement en Physiopathologie Cardio-Vasculaire", Université de Lorraine, 30 Rue Lionnois, Nancy 54000, France.
authors: Maria G
authors: MG
authors: Stathopoulou
authors: Pedro
authors: P
authors: Monteiro
authors: Payman
authors: P
authors: Shahabi
authors: Eva
authors: E
authors: Peñas-Lledó
authors: Said
authors: S
authors: El Shamieh
authors: Luís
authors: L
authors: Silva Santos
authors: Nathalie
authors: N
authors: Thilly
authors: Gerard
authors: G
authors: Siest
authors: Adrián
authors: A
authors: Llerena
authors: Sophie
authors: S
authors: Visvikis-Siest
mesh_terms: D000328:Adult; D000368:Aged; D000789:Angina, Unstable / Q000188:drug therapy; D001189:Aryl Hydrocarbon Hydroxylases / Q000502:physiology*; D001794:Blood Pressure / Q000187:drug effects*; D002121:Calcium Channel Blockers / Q000494:pharmacology* / Q000627:therapeutic use; D000077144:Clopidogrel; D065731:Cytochrome P-450 CYP2C19; D004357:Drug Synergism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy; D013988:Ticlopidine / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D002121:Calcium Channel Blockers; D000077144:Clopidogrel; D001189:Aryl Hydrocarbon Hydroxylases; C045793:CYP2C19 protein, human; D065731:Cytochrome P-450 CYP2C19; D013988:Ticlopidine
keywords: Blood pressure; CYP2C19 polymorphism; Calcium-channel blockers; Clopidogrel; Synergy