title: TrioVis: a visualization approach for filtering genomic variants of parent-child trios.
abstract: CONCLUSIONS
  TrioVis is a visual analytics tool developed for filtering on coverage and variant frequency for genomic variants from exome sequencing of parent-child trios. In TrioVis, the variant data are organized by grouping each variant based on the laws of Mendelian inheritance. Taking three Variant Call Format files as input, TrioVis allows the user to test different coverage thresholds (i.e. different levels of stringency), to find the optimal threshold values tailored to their hypotheses and to gain insights into the global effects of filtering through interaction.
  
  
  BACKGROUND
  Executables, source code and sample data are available at https://bitbucket.org/biovizleuven/triovis. Screencast is available at http://vimeo.com/user6757771/triovis.
  
  
  BACKGROUND
  ryo.sakai@esat.kuleuven.be.
authors: Department of Electrical Engineering-ESAT, KU Leuven, SCD-SISTA, Leuven 3001, Belgium. ryo.sakai@esat.kuleuven.be
authors: Ryo
authors: R
authors: Sakai
authors: Alejandro
authors: A
authors: Sifrim
authors: Andrew
authors: A
authors: Vande Moere
authors: Jan
authors: J
authors: Aerts
mesh_terms: D002648:Child; D003196:Computer Graphics; D059472:Exome; D014644:Genetic Variation; D023281:Genomics / Q000379:methods; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D010290:Parents; D017422:Sequence Analysis, DNA; D012984:Software
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