title: Comparison between the efficacy of ginger and sumatriptan in the ablative treatment of the common migraine.
abstract: Frequency and torment caused by migraines direct patients toward a variety of remedies. Few studies to date have proposed ginger derivates for migraine relief. This study aims to evaluate the efficacy of ginger in the ablation of common migraine attack in comparison to sumatriptan therapy. In this double-blinded randomized clinical trial, 100 patients who had acute migraine without aura were randomly allocated to receive either ginger powder or sumatriptan. Time of headache onset, its severity, time interval from headache beginning to taking drug and patient self-estimation about response for five subsequent migraine attacks were recorded by patients. Patients(,) satisfaction from treatment efficacy and their willingness to continue it was also evaluated after 1 month following intervention. Two hours after using either drug, mean headaches severity decreased significantly. Efficacy of ginger powder and sumatriptan was similar. Clinical adverse effects of ginger powder were less than sumatriptan. Patients' satisfaction and willingness to continue did not differ. The effectiveness of ginger powder in the treatment of common migraine attacks is statistically comparable to sumatriptan. Ginger also poses a better side effect profile than sumatriptan.
authors: Zanjan University Of Medical Sciences, VALI-e-ASR Hospital, Neurology Department, Zanjan, Iran.
authors: Mehdi
authors: M
authors: Maghbooli
authors: Farhad
authors: F
authors: Golipour
authors: Alireza
authors: A
authors: Moghimi Esfandabadi
authors: Mehran
authors: M
authors: Yousefi
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000700:Analgesics / Q000627:therapeutic use*; D000932:Antiemetics / Q000627:therapeutic use; D004311:Double-Blind Method; D005260:Female; D020939:Zingiber officinale / Q000737:chemistry*; D006801:Humans; D008297:Male; D020326:Migraine without Aura / Q000188:drug therapy*; D017060:Patient Satisfaction; D028321:Plant Preparations / Q000627:therapeutic use*; D018170:Sumatriptan / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000700:Analgesics; D000932:Antiemetics; D028321:Plant Preparations; D018170:Sumatriptan
keywords: common migraine; ginger; sumatriptan