title: Preventive agents for migraine: focus on the antiepileptic drugs.
abstract: Migraine is among the 10 most disabling disorders worldwide. It is characterized by episodes of moderate or severe headaches with various degree of disability, resulting in a considerable health burden upon the sufferers and their family. The objective of this article is to review the use of prophylaxis with antiepileptic drugs. Particular focus is given to their mechanism of action, metabolism, pharmacokinetics, safety profile, efficacy and to provide a summary of the most relevant clinical studies and patient preference.
authors: Department of Neurology, Ziv Medical Center, affiliated to Bar Ilan University, Safed 13100, Israel.
authors: R
authors: R
authors: Shahien
authors: K
authors: K
authors: Beiruti
keywords: antiepileptic drugs; migraine; prophylaxis
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