title: Signalling change: signal transduction through the decades.
abstract: The past few years have marked significant anniversaries in signal transduction, including the identification of classic growth factors and morphogens, the notion of protein modification through phosphorylation and the characterization of protein interaction domains. Here, six researchers reflect on the context in which these discoveries were made, and how our concept of cell signalling has evolved during the past three decades.
authors: Friedrich Miescher Institute for Biomedical Research, and University of Basel, Basel, Switzerland. nancy.hynes@fmi.ch
authors: Nancy E
authors: NE
authors: Hynes
authors: Philip W
authors: PW
authors: Ingham
authors: Wendell A
authors: WA
authors: Lim
authors: Christopher J
authors: CJ
authors: Marshall
authors: Joan
authors: J
authors: Massagué
authors: Tony
authors: T
authors: Pawson
mesh_terms: D000818:Animals; D035843:Biomedical Research / Q000266:history* / Q000379:methods; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism*; D010766:Phosphorylation; D011499:Protein Processing, Post-Translational; D015398:Signal Transduction
chemical_list: D036341:Intercellular Signaling Peptides and Proteins
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