title: Cord blood haemoglobin and ferritin concentrations in newborns of anaemic and non-anaemic mothers in Lagos, Nigeria.
abstract: BACKGROUND
  Pre-delivery haemoglobin and serum ferritin concentrations of anaemic and non-anaemic mothers were determined, and cord blood haemoglobin and serum ferritin concentrations of their newborns were compared. This is to establish the mean values for pre-delivery haemoglobin and serum ferritin concentrations of anaemic and non-anaemic mothers and the cord blood haemoglobin and serum ferritin concentrations of their newborns at term.
  
  
  METHODS
  A case-control study was done involving 142 pregnant women and their newborns. They were divided into two groups - the anaemic group (n = 65) and the non-anaemic (n = 77) group. Five millilitres of blood was collected from each woman and 2 ml was collected from the cord of their newborns into ethylenediaminetetraacetic acid (EDTA) bottle and plain bottle for full blood count analysis and ferritin assay, respectively.
  
  
  RESULTS
  The mean pre-delivery haemoglobin concentrations of the women in anaemic group and non-anaemic group were 9.5 ± 1.01 g/dl and 12.15 ± 1.07 g/dl, respectively, and their mean serum ferritin concentrations were 64.45 ± 138.76 μg/l and 32.83 ± 35.36 μg/l, respectively. The mean cord blood haemoglobin concentrations for anaemic and for non-anaemic groups were 12.54 ± 2.54 g/dl and 13.44 ± 2.23 g/dl (P = 0.02), respectively, and the mean cord blood serum ferritin concentrations (non-anaemic, 69.38 ± 78.88 μg/l; anaemic, 7.26 ± 115.60 μg/l) (P = 0.00) were higher in the newborns of non-anaemic than of anaemic mothers. Significant association was found between maternal anaemia and cord blood ferritin concentrations (P = 0.025).
  
  
  CONCLUSIONS
  Maternal anaemia has significant effects on cord blood haemoglobin and serum ferritin concentrations.
authors: Department of Haematology and Blood Transfusion, College of Medicine, University of Lagos, Nigeria.
authors: Adewumi
authors: A
authors: Adediran
authors: Abidoye
authors: A
authors: Gbadegesin
authors: Titilope A
authors: TA
authors: Adeyemo
authors: Akinsegun
authors: A
authors: Akinbami
authors: Vincent
authors: V
authors: Osunkalu
authors: Ann
authors: A
authors: Ogbenna
authors: Alani S
authors: AS
authors: Akanmu
keywords: Anaemia; haemoglobin; newborn babies; pregnant women; serum ferritin
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