title: [Gastrointestinal histoplasmosis: an atypical presentation].
abstract: Histoplasmosis is a systemic mycosis caused by Histoplasma capsulatum. It is an endemic disease in the American continent. It is spread hematogenously and any organ can be affected. It is more frequent in immunodeficient patients and the most common opportunist mycosis associated with HIV Exclusive gastrointestinal involvement is rare and invariably mortal without treatment. It is considered to be impossible to diagnose the disease based on the macroscopic aspect of lesions. We report a 43-year-old male in apparent good health status who was admitted with intermittent proctorrhagia of one year of evolution associated to burning proctalgia, without any further symptoms. A videocolonoscopy (VCC) with proctologic exam was conducted The patient was warned about the potential orificial origin of the bleeding and the importance of screening for colorectal neoplasia. The proctologic exam revealed internal congestive hemorrhoids. VCC showed during the routine exploration of the terminal ileon lesions both in that level and rectum, although of a different morphology. The colon had normal endoscopic appearance. Biopsies of both lesions identified Histoplasma. Later studies diagnosed HIV/AIDS and the patient was referred to the infectology department to complete diagnostic tests and begin treatment of both diseases. In conclusion, we present an atypical case of this mycosis because of its exclusive gastrointestinal allocation, in anasymptomatic patient, in apparent good health, with unknown HIV/AIDS, who was admitted because of a proctorrhagia of orificial origin. Endoscopic biopsies of lesions of different morphologies, located in the terminal ileon and rectum, allowed the diagnosis of this disease, that had no clinical expression. This casual endoscopic diagnosis enabled to change the life expectancy of the patient. We consider that the described endoscopic lesions in rectum are of a particular morphology and can rarely be found in other pathologies. The diffusion of these images could warn other endoscopists of these phenomena.
authors: CEGA, Centro Privado de Gastroenterología, Campana, Provincia de Buenos Aires, Argentina. rabarros.cega@gmail.com
authors: Roberto Augusto
authors: RA
authors: Barros
authors: María José
authors: MJ
authors: Monteverde
authors: Santiago de
authors: Sd
authors: dElizalde
authors: Augusto Sebastián
authors: AS
authors: Barros
authors: Roberto Federico
authors: RF
authors: Barros
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000382:microbiology; D000328:Adult; D005767:Gastrointestinal Diseases / Q000175:diagnosis* / Q000382:microbiology; D006660:Histoplasmosis / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008551:Melena / Q000175:diagnosis* / Q000382:microbiology