title: Fluorescence lifetime detection in turbid media using spatial frequency domain filtering of time domain measurements.
abstract: It is demonstrated that high spatial frequency filtering of time domain fluorescence signals can allow efficient detection of intrinsic fluorescence lifetimes from turbid media and the rejection of diffuse excitation leakage. The basis of this approach is the separation of diffuse fluorescence signals into diffuse and fluorescent components with distinct spatiotemporal behavior.
authors: Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA. ankumar@nmr.mgh.harvard.edu
authors: Anand T N
authors: AT
authors: Kumar
mesh_terms: D005456:Fluorescent Dyes / Q000737:chemistry; D008027:Light; D019047:Phantoms, Imaging; D062211:Spatio-Temporal Analysis; D013050:Spectrometry, Fluorescence / Q000379:methods*; D013997:Time Factors
chemical_list: D005456:Fluorescent Dyes
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