title: Case series: conditions inhibiting eruption of permanent first molars.
abstract: OBJECTIVE
  The purpose of this study was to evaluate the radiological and histopathological findings of 11 patients with unerupted first molars to verify the factors obstructing spontaneous eruption.
  
  
  METHODS
  The patients' clinical, radiological, and histopathological data were evaluated retrospectively to determine histopathological diagnosis, radiographic findings, methods of surgical management, and postoperative course.
  
  
  RESULTS
  This study involved 4 male and 7 female patients (mean age=9.5 years old). Nine cases involved the mandible. The patients' histopathological diagnoses included 3 odontogenic tumors, 2 odontogenic cysts, and 6 hyperplastic dental follicles. Radiographically, 10 cases showed characterless enlargement of the follicular space, while only 1 displayed radiopaque bodies. One patient with a tumor underwent enucleation, and 1 with a cyst underwent cystectomy and tooth extraction. The others underwent wide excision or partial excision of the surrounding tissue at the top of the impacted tooth. Tumor relapse was observed in 3 cases.
  
  
  CONCLUSIONS
  Surgeons should perform aggressive treatment for patients with unerupted teeth because spontaneous eruption is rare in cases involving non-neoplastic lesions such as hyperplastic dental follicles.
authors: Department of Oral Diagnosis and Dentomaxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan.
authors: Hidenobu
authors: H
authors: Matsuzaki
authors: Yoshinobu
authors: Y
authors: Yanagi
authors: Naoki
authors: N
authors: Katase
authors: Hitoshi
authors: H
authors: Nagatsuka
authors: Marina
authors: M
authors: Hara
authors: Masakazu
authors: M
authors: Ashida
authors: Teruhisa
authors: T
authors: Unetsubo
authors: Akiko
authors: A
authors: Sato
authors: Mariko
authors: M
authors: Fujita
authors: Toshihiko
authors: T
authors: Takenobu
authors: Jun-ichi
authors: J
authors: Asaumi
mesh_terms: D000293:Adolescent; D002648:Child; D003795:Dental Sac / Q000473:pathology; D003803:Dentigerous Cyst / Q000150:complications / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006965:Hyperplasia; D008297:Male; D008336:Mandibular Diseases / Q000150:complications / Q000601:surgery; D008339:Mandibular Neoplasms / Q000150:complications / Q000601:surgery; D008439:Maxillary Diseases / Q000150:complications / Q000601:surgery; D008441:Maxillary Neoplasms / Q000150:complications / Q000601:surgery; D019060:Minimally Invasive Surgical Procedures / Q000379:methods; D008963:Molar / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009808:Odontogenic Tumors / Q000150:complications / Q000601:surgery; D011859:Radiography; D012189:Retrospective Studies; D014081:Tooth Extraction / Q000379:methods; D014095:Tooth, Impacted / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D014097:Tooth, Unerupted / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery