title: A cellular logic circuit for the detection of bacterial pore-forming toxins.
abstract: We present a cellular logic circuit for deciphering the profiles of toxin production in B. cereus, using multiple readout techniques based on the pore formation on the cell membrane. This new assay enables the simultaneous detection of seven biomarkers in pathogenic strains from various samples.
authors: Institute of Food Safety, Faculty of Veterinary Medicine, Ludwig-Maximilians-University Munich, Schönleutnerstr. 8, 85764 Oberschleissheim, Germany. zhukcau@gmail.com
authors: Kui
authors: K
authors: Zhu
authors: Ulaş
authors: U
authors: Acaröz
authors: Erwin
authors: E
authors: Märtlbauer
mesh_terms: D000818:Animals; D001409:Bacillus cereus / Q000378:metabolism*; D001427:Bacterial Toxins / Q000032:analysis* / Q000378:metabolism / Q000633:toxicity*; D015374:Biosensing Techniques / Q000295:instrumentation*; D002462:Cell Membrane / Q000382:microbiology*; D002470:Cell Survival; D002522:Chlorocebus aethiops; D004867:Equipment Design; D018675:Toxicity Tests / Q000295:instrumentation*; D014709:Vero Cells
chemical_list: D001427:Bacterial Toxins