title: Effects of endosulfan pesticide on toad.
abstract: The lethal and sublethal toxicity of Endosulfan on the African toad, Bufo regularis were evaluated to assess changes in behaviour and energy reserves. 96 hours LC50 was 0.730 mg/l while the estimated safe concentration was 0.07 mg/L indicating the high toxicity of the insecticide. Toads exposed to lethal concentrations of endosulfan showed dose-dependent behavioural abnormalities with more pronounced poisoning symptoms occurring at higher concentrations. The pesticide caused differential increase in serum glucose levels with a concomitant reduction in liver glycogen indicating disorders in carbohydrate metabolism due to pesticide induced stress and hence can serve as suitable biomarkers in pesticide toxicity studies.
authors: Department of Animal and Environmental Biology, Faculty of Life Sciences, University of Benin, Benin City, Edo State, Nigeria. isquared27@yahoo.com
authors: Tongo
authors: T
authors: Isioma
authors: Ezemonye
authors: E
authors: Lawrence
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000187:drug effects; D002025:Bufonidae / Q000097:blood; D004726:Endosulfan / Q000633:toxicity*; D006003:Glycogen / Q000378:metabolism; D007306:Insecticides / Q000633:toxicity*; D008099:Liver / Q000378:metabolism; D011041:Poisoning
chemical_list: D001786:Blood Glucose; D007306:Insecticides; D006003:Glycogen; D004726:Endosulfan