title: Subependymal giant cell astrocytoma with atypical clinical and pathological features: a diagnostic pitfall.
abstract: Subependymal giant cell astrocytoma (SEGA) is benign, slowly growing tumor linked to the tuberous sclerosis complex. It almost always occurs near the foramen of Monro. Parenchymal extension and worrisome histological features, such as necrosis, mitoses, microvascular proliferation and pleomorphism are unusual in these tumors, but can occur rarely. A case of SEGA is presented, in a patient with no signs of tuberous sclerosis so far, with atypical imaging findings and areas of necrosis found microscopically. These worrisome features initially led to the false diagnosis of glioblastoma. The differential diagnosis of SEGA is discussed.
authors: Department of Pathology, L Pasteur's University Hospital, Kosice, Slovakia. svajdler@yahoo.com
authors: Marián
authors: M
authors: Svajdler
authors: Ladislav
authors: L
authors: Deák
authors: Boris
authors: B
authors: Rychlý
authors: Peter
authors: P
authors: Talarčík
authors: Lucia
authors: L
authors: Fröhlichová
mesh_terms: D001254:Astrocytoma / Q000175:diagnosis* / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant