title: Mesonephric adenocarcinoma with a sarcomatous component, a notable subtype of cervical carcinosarcoma: a case report and review of the literature.
abstract: Carcinosarcoma of the uterine cervix is less common than its counterpart in the uterine corpus. On the other hand, mesonephric adenocarcinoma is also a rare neoplasm in the uterine cervix, and it has been reported that mesonephric adenocarcinomas are often accompanied by sarcomatous components. We present a case of mesonephric adenocarcinoma with a sarcomatous component which arose in a 63-year-old postmenopausal woman. The hysterectomy specimen grossly showed an exophytic mass measuring 1.8 cm in the uterine cervix. Histologically, diffuse mesonephric hyperplasia and adenocarcinoma with malignant spindle cell proliferation was recognized, and therefore the tumor was diagnosed as "mesonephric adenocarcinoma with a sarcomatous component." The review of the literature of cervical carcinosarcoma and cervical mesonephric adenocarcinoma revealed that 16% of cervical carcinosarcoma is of mesonephric duct origin, and that mesonephric adenocarcinoma seems to be more likely to have sarcomatous change. We think the presence of a sarcomatous component in the cervical biopsy specimen could be helpful in the diagnosis of mesonephric duct origin.
authors: Shiori
authors: S
authors: Meguro
authors: Masanori
authors: M
authors: Yasuda
authors: Michio
authors: M
authors: Shimizu
authors: Akira
authors: A
authors: Kurosaki
authors: Keiichi
authors: K
authors: Fujiwara
mesh_terms: D018195:Adenosarcoma / Q000473:pathology* / Q000601:surgery; D001706:Biopsy; D002296:Carcinosarcoma / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007044:Hysterectomy; D008197:Lymph Node Excision; D008875:Middle Aged; D009095:Mullerian Ducts / Q000473:pathology; D010052:Ovariectomy; D058994:Salpingectomy; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery; D014594:Uterine Neoplasms / Q000473:pathology* / Q000601:surgery
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