title: Assisted tandem catalytic cross metathesis-oxidation: in one flask from styrenes to 1,2-diketones and further to quinoxalines.
abstract: 1,2-Diketones were synthesized from styrenes by combining a cross metathesis and a Ru-catalyzed alkene oxidation to an assisted tandem catalytic sequence. The synthesis relies on the use of just one metathesis precatalyst, which was in situ converted to the oxidation catalyst by addition of an alkyl hydroperoxide as a chemical trigger and oxidant. The one-flask sequence can be extended beyond 1,2-diketones to quinoxalines, by condensation of the oxidation products with ortho-phenylenediamine.
authors: Universitaet Potsdam, Institut fuer Chemie (Organische Synthesechemie), Karl-Liebknecht-Strasse 24-25, D-14476 Potsdam-Golm, Germany. bernd.schmidt@uni-potsdam.de
authors: Bernd
authors: B
authors: Schmidt
authors: Stefan
authors: S
authors: Krehl
authors: Sylvia
authors: S
authors: Hauke
mesh_terms: D002384:Catalysis; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction; D011810:Quinoxalines / Q000138:chemical synthesis* / Q000737:chemistry; D013343:Styrenes / Q000737:chemistry*
chemical_list: D007659:Ketones; D011810:Quinoxalines; D013343:Styrenes