title: Unusual features in four canine meningiomas.
abstract: Several subtypes of canine meningioma are recognized. This report describes four canine meningiomas with previously unreported features. The four affected dogs were of different breeds. Three of the affected dogs were male and aged 7-10 years. In one dog, age and gender were not recorded. Meningiomas were located intracranially (three dogs) or within the vertebral canal (one dog). Two meningiomas resembled gemistocytic astrocytomas, while one had focal features of a rhabdoid tumour; these three meningiomas also contained amyloid deposits. The fourth tumour, a secretory meningioma, was rich in amianthoid fibres (i.e. unusual collagen deposits containing giant collagen fibres). All of these features are also described in human meningiomas.
authors: Department of Pathology and Pathogen Biology, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK. sandra.schoeniger@vetmed.uni-leipzig.de
authors: S
authors: S
authors: Schöniger
authors: L
authors: L
authors: Woolford
authors: L
authors: L
authors: Jutras
authors: E
authors: E
authors: Head
authors: A
authors: A
authors: de Lahunta
authors: B A
authors: BA
authors: Summers
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000662:veterinary*; D008579:Meningioma / Q000473:pathology / Q000662:veterinary*
chemical_list: D014408:Biomarkers, Tumor
keywords: dog; gemistocyte-like tumour cells; meningioma; rhabdoid tumour