title: [2-Acet-oxy-3-(naphthalen-1-yl-oxy)prop-yl](propan-2-yl)aza-nium chloride monohydrate.
abstract: The title compound, C18H24NO3 (+)·Cl(-)·H2O, was synthesized by the reaction of propranolol hydro-chloride with acetyl chloride in chloro-form followed by slow evaporation in air. In the cation, the dihedral angle between the planes of the naphthalene ring system and the acetate group is 71.1 (2)°. An intra-molecular N-H⋯O hydrogen bond results in the formation of a non-planar pseudo-ring, with the ether O and the H atom displaced by -1.328 (2) and 0.65 Å, respectively, from the plane of the other ring atoms. The cation and anion are linked by an N-H⋯Cl hydrogen bond. The water molecule is linked to a methyl H atom by C-H⋯O hydrogen bond.
authors: Department of Chemical and Pharmaceutical Engineering, Southeast University ChengXian College, Nanjing 210088, People's Republic of China.
authors: Yuan-Yuan
authors: YY
authors: Liu
authors: Guang-Hui
authors: GH
authors: Xu
authors: Zheng-Jie
authors: ZJ
authors: Li
authors: Hong-Yu
authors: HY
authors: Xu
authors: Chang-Qing
authors: CQ
authors: Gu
references: Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22
references: 18156677
references: N Biotechnol. 2010 Dec 31;27(6):844-50
references: 20667519