title: Paediatric head and neck cancers in Nigeria: Implications for treatment planning in resource limited settings.
abstract: BACKGROUND
  The head and neck (H/N) is a common site for childhood cancers. This study examined all cases of H/N childhood cancers diagnosed in a major teaching hospital in Nigeria over 18 years to determine patterns of broad lineage cancer groups.
  
  
  METHODS
  Primary pediatric childhood malignancies diagnosed between 1990 and 2008 were analysed. Logistic regression models were fitted to determine significant clinical correlates of childhood cancer.
  
  
  RESULTS
  Lymphomas were the commonest cancers (49.5%). After controlling for site and age, there was no significant difference in the incidence of Burkitt's lymphoma (BL) by sex (P=0.423). The jaw bones (mandible and maxilla) were the commonest sites in the H/N for involvement of BL, with over 20 times the odds of occurrence when compared to other non-jaw sites of the H/N region (Adjusted Odds Ratio [AOR]=21.41, P<0.001). Among the jaw bones, there was no significant difference in the occurrence of BL (P=0.860).
  
  
  CONCLUSIONS
  Lymphomas are the commonest cancer group among children in Nigeria. In resource limited settings where diagnoses depend majorly on clinical intuition, an awareness of predictors of a disease can shorten the time spent on arriving at a working diagnosis and guide the immediate choice of investigations and treatment.
authors: Department of Oral Pathology, University College Hospital Ibadan, Nigeria.
authors: Adisa O
authors: AO
authors: Akinyele
authors: Agaku T
authors: AT
authors: Israel
authors: E E U
authors: EE
authors: Akang
keywords: Cancer; Nigeria; children; lymphoma
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