title: Metabolomics of cereals under biotic stress: current knowledge and techniques.
abstract: Prone to attacks by pathogens and pests, plants employ intricate chemical defense mechanisms consisting of metabolic adaptations. However, many plant attackers are manipulating the host metabolism to counteract defense responses and to induce favorable nutritional conditions. Advances in analytical chemistry have allowed the generation of extensive metabolic profiles during plant-pathogen and pest interactions. Thereby, metabolic processes were found to be highly specific for given tissues, species, and plant-pathogen/pest interactions. The clusters of identified compounds not only serve as base in the quest of novel defense compounds, but also as markers for the characterization of the plants' defensive state. The latter is especially useful in agronomic applications where meaningful markers are essential for crop protection. Cereals such as maize make use of their metabolic arsenal during both local and systemic defense responses, and the chemical response is highly adapted to specific attackers. Here, we summarize highlights and recent findings of metabolic patterns of cereals under pathogen and pest attack.
authors: Institute of Biology, University of Neuchâtel Neuchâtel, Switzerland.
authors: Dirk
authors: D
authors: Balmer
authors: Victor
authors: V
authors: Flors
authors: Gaetan
authors: G
authors: Glauser
authors: Brigitte
authors: B
authors: Mauch-Mani
keywords: chemical analytical techniques; chemical defense; metabolic profile; monocots; phytoalexins; secondary metabolites
references: Plant J. 2008 Oct;56(2):181-195
references: 18564380
references: Plant Signal Behav. 2009 Jul;4(7):636-8
references: 19820311
references: Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6198-203
references: 20308540
references: Plant Physiol. 2010 Jun;153(2):678-92
references: 20357140
references: Plant Cell. 2012 Jan;24(1):322-35
references: 22267486
references: BMC Bioinformatics. 2005 Jul 18;6:179
references: 16026613
references: Nat Protoc. 2006;1(1):387-96
references: 17406261
references: Plant Biotechnol J. 2010 May 1;8(4):436-51
references: 20132517
references: Phytochem Anal. 2010 Jan-Feb;21(1):33-47
references: 19927296
references: Genetics. 1998 Aug;149(4):1997-2006
references: 9691053
references: J Chem Ecol. 2005 Aug;31(8):1887-905
references: 16222814
references: J Chem Ecol. 1987 Apr;13(4):889-906
references: 24302054
references: Nat Chem Biol. 2009 May;5(5):308-16
references: 19377457
references: PLoS One. 2012;7(7):e40695
references: 22866179
references: Nat Protoc. 2008;3(6):1001-12
references: 18536647
references: Trends Biotechnol. 2011 Jan;29(1):33-40
references: 21030098
references: Annu Rev Plant Biol. 2010;61:463-89
references: 19152489
references: Anal Chem. 2004 Mar 15;76(6):1738-45
references: 15018577
references: Phytochemistry. 2010 Apr;71(5-6):590-7
references: 20138320
references: Electrophoresis. 2009 Jan;30(1):276-91
references: 19107702
references: Anal Chem. 2006 Feb 1;78(3):779-87
references: 16448051
references: Anal Chem. 2009 Apr 15;81(8):3079-86
references: 19301908
references: Metabolites. 2011 Dec 15;1(1):64-78
references: 24957244
references: Mol Cells. 2009 Nov 30;28(5):431-9
references: 19904499
references: J AOAC Int. 2011 Jan-Feb;94(1):51-70
references: 21391481
references: Methods Mol Biol. 2012;860:31-49
references: 22351169
references: J Proteome Res. 2012 Jan 1;11(1):320-30
references: 22017194
references: Annu Rev Phytopathol. 1999;37:285-306
references: 11701825
references: Phytopathology. 2005 Oct;95(10):1116-21
references: 18943462
references: Science. 2002 Apr 5;296(5565):92-100
references: 11935018
references: J Exp Bot. 2012 May;63(9):3429-44
references: 22213816
references: J Chromatogr A. 2013 May 31;1292:151-9
references: 23274073
references: Nat Prod Commun. 2009 Oct;4(10):1417-30
references: 19911581
references: J Chem Ecol. 2011 Aug;37(8):846-56
references: 21701847
references: Biosci Biotechnol Biochem. 2004 Apr;68(4):873-80
references: 15118317
references: Cell Mol Life Sci. 2012 Oct;69(19):3225-43
references: 22885821
references: Bioanalysis. 2011 Jan;3(2):121-3
references: 21250839
references: Curr Med Chem. 2013;20(8):1056-90
references: 23210790
references: Phys Biol. 2008 Feb 20;5(1):011001
references: 18367780
references: Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10092-6
references: 19520825
references: Plant J. 2004 Oct;40(1):151-63
references: 15361149
references: Clin Chim Acta. 1971 Sep;34(2):135-44
references: 5113555
references: Trends Plant Sci. 2006 Oct;11(10):508-16
references: 16949327
references: Phytochemistry. 2003 Jan;62(1):1-4
references: 12475612
references: EXS. 2007;97:195-212
references: 17432269
references: Plant Mol Biol. 2007 Apr;63(6):847-60
references: 17273822
references: Phytochem Anal. 2010 Jan-Feb;21(1):14-21
references: 19904731
references: Plant J. 2011 Dec;68(5):901-11
references: 21838747
references: Mol Plant Microbe Interact. 2005 Dec;18(12):1318-24
references: 16478051
references: Plant J. 2013 Apr;74(2):213-25
references: 23302050
references: Phytochemistry. 2003 Mar;62(6):817-36
references: 12590110
references: J Agric Food Chem. 2009 Mar 11;57(5):1677-96
references: 19199602
references: Phytochemistry. 2008 Jun;69(9):1795-813
references: 18472115
references: Mass Spectrom Rev. 2007 Jan-Feb;26(1):51-78
references: 16921475
references: Plant Physiol. 2010 Aug;153(4):1597-607
references: 20522723
references: Proc Natl Acad Sci U S A. 2005 Nov 15;102(46):16892-7
references: 16263921
references: Plant J. 2009 Sep;59(5):723-37
references: 19453445
references: Int J Mol Sci. 2009 Jul 31;10(8):3400-19
references: 20111686
references: Plant J. 2009 Jul;59(2):292-302
references: 19392694
references: J Sep Sci. 2010 Feb;33(3):290-304
references: 20087872
references: Talanta. 2006 Nov 15;70(4):797-804
references: 18970842
references: Plant J. 2008 Jul;55(2):348-60
references: 18397372
references: Mol Plant Pathol. 2010 Nov;11(6):769-82
references: 21029322
references: Plant Physiol. 2011 Apr;155(4):1752-61
references: 21350035
references: Front Plant Sci. 2011 Aug 22;2:39
references: 22645534
references: Phytopathology. 2004 Nov;94(11):1207-14
references: 18944456
references: Phytochem Anal. 2012 Sep-Oct;23(5):508-12
references: 22271502
references: Plant Physiol. 2011 Sep;157(1):317-27
references: 21730199
references: Nat Protoc. 2010 Mar;5(3):536-49
references: 20203669
references: Plant Sci. 2012 Oct;195:54-70
references: 22920999
references: Anal Biochem. 2002 Feb 15;301(2):298-307
references: 11814300
references: Curr Opin Plant Biol. 2004 Apr;7(2):196-201
references: 15003221
references: Plant Cell Environ. 2013 Mar;36(3):621-39
references: 22913585
references: Plant Cell. 2007 Feb;19(2):706-24
references: 17322409