title: [Effects of soy protein supplement on overweight and obese population: meta-analysis of randomized controlled trials].
abstract: OBJECTIVE
  To study the effects of soy protein supplement on overweight and obese population.
  
  
  METHODS
  Randomized controlled trials (RCT) published from January 1988 to May 2012 observing the effect of soy protein supplement on overweight and obese population were collected. Meta-analysis was applied to estimate the standardized mean difference (WMD) and 95% confidence interval (95% CI).
  
  
  RESULTS
  Among 13 RCTs, the number of the studies observing change of body weight, body mass index (BMI), fat mass and waist circumference were 12, 7, 7 and 11, respectively. Compared with the control group, the combined WMD (95% CI) of soy protein supplemented was - 1.04 kg [( -1.97) - ( -0.11)], -0.19 kg/m2 [(-0.41) - (0.02)], -0.99 kg [(-1.73) - (-0.24)] and - 0.94 cm [(-1.66) - (-0.21)], respectively. However, the protective effect of soy protein was only observed among studies conducted in Western population, but not in Asian population.
  
  
  CONCLUSIONS
  Soy protein supplementation significantly decreased body weight, fat mass and waist circumference in overweight and obese population.
authors: Department of Nutrition and Food Hygiene, School of Public Health, Soochow University, Suzhou 215123, China. 403923179@qq.com
authors: Jing
authors: J
authors: Wu
authors: Jiayi
authors: J
authors: Dong
authors: Xia
authors: X
authors: Jiang
authors: Liqiang
authors: L
authors: Qin
mesh_terms: D015992:Body Mass Index; D001835:Body Weight; D019587:Dietary Supplements; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000178:diet therapy*; D050177:Overweight / Q000178:diet therapy*; D016032:Randomized Controlled Trials as Topic; D030262:Soybean Proteins / Q000008:administration & dosage*
chemical_list: D030262:Soybean Proteins