title: Highly regioselective syntheses of substituted triphenylenes from 1,2,4-trisubstituted arenes via a co-catalyzed intermolecular alkyne cyclotrimerization.
abstract: Herein, we report the development of a new method for the syntheses of substituted triphenylenes from the corresponding 1,2,4-trisubstituted arenes, which were themselves generated in a highly regioselective manner according to an intermolecular alkyne cyclotrimerization reaction that was catalyzed by a novel Co-TMTU complex. This highly regioselective reaction for the formation of 1,2,4-trisubstituted arenes will be a valuable addition to the plethora of tools already available to synthetic chemists and encourage further mechanistic studies of this important alkyne trimerization process.
authors: Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Peking-Tsinghua Center for Life Sciences at College of Chemistry, Peking University, Beijing 100871, China.
authors: Lingmin
authors: L
authors: Xu
authors: Ruocheng
authors: R
authors: Yu
authors: Yuefan
authors: Y
authors: Wang
authors: Jiahua
authors: J
authors: Chen
authors: Zhen
authors: Z
authors: Yang
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D002384:Catalysis; D002911:Chrysenes / Q000138:chemical synthesis* / Q000737:chemistry; D003035:Cobalt / Q000737:chemistry*; D003500:Cyclization; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000480:Alkynes; D002911:Chrysenes; C009590:triphenylene; D003035:Cobalt