title: Retention of halogenated solutes on stationary phases containing heavy atoms.
abstract: To examine the effects of weak intermolecular interactions on solid-phase extraction (SPE) and chromatographic separation, we synthesized some novel stationary phases with a heavy atom effect layer by immobilizing halogenated aromatic rings and hydroxyl groups onto the surface of a hydrophilic base polymer. Using SPE cartridges packed with the functionalized materials, we found that the heavy atom stationary phases could selectively retain halophenols in organic solvents, such as 1-propanol which blocks the hydrogen bonding, or acetonitrile which blocks the π-π interaction. The extraction efficiency of the materials toward the halophenols depended on the dipole moments of phenoxy groups present as functional groups. On the other hand, the extraction efficiency of solutes toward the functional group depended on their molar refractions, i.e., induced dipole moments. The retention of the solutes to the stationary phase ultimately depended on not only strong intermolecular interactions, but also the effects of weak interactions such as the dispersion force.
authors: College of Bioscience and Biotechnology, Chubu University, 1200 Matsumotocho, Kasugai-shi, Aichi 487-8501, Japan. gr12805-5449@sti.chubu.ac.jp
authors: Toshio
authors: T
authors: Miwa
authors: Atsushi
authors: A
authors: Yamamoto
authors: Mitsuru
authors: M
authors: Saito
authors: Yoshinori
authors: Y
authors: Inoue
mesh_terms: D000433:1-Propanol / Q000737:chemistry*; D006841:Hydrocarbons, Aromatic / Q000737:chemistry*; D006846:Hydrocarbons, Halogenated / Q000737:chemistry*; D006860:Hydrogen Bonding
chemical_list: D006841:Hydrocarbons, Aromatic; D006846:Hydrocarbons, Halogenated; D000433:1-Propanol
references: Anal Bioanal Chem. 2012 Apr;403(1):75-92
references: 22278073
references: J Phys Chem A. 2005 Jun 16;109(23):5186-92
references: 16833874
references: Anal Chem. 2011 Jun 15;83(12):4440-52
references: 21524128
references: J Food Sci. 2011 Mar;76(2):R69-75
references: 21535786
references: Shokuhin Eiseigaku Zasshi. 2010;51(2):58-64
references: 20453455
references: Anal Bioanal Chem. 2011 Mar;399(9):3157-76
references: 21046088
references: J Am Chem Soc. 2003 Nov 12;125(45):13836-49
references: 14599224