title: Synchronous quadruple primary tumors of thyroid, breast, pancreas, and stomach: a case report.
abstract: We herein present the first case to be reported of synchronous quadruple primary cancer of the thyroid, breast, pancreas and stomach in a 70-year-old female. Fluorine-18-fluorodeoxyglucose (FDG)-positron-emission tomography/computed tomography (PET/CT) revealed increased FDG activity in the thyroid, left breast, pancreatic body and antrum of the stomach. To make a definitive diagnosis of synchronous quadruple primary tumors, ultrasound-guided fine-needle aspiration (FNA) cytology and biopsy of the thyroid, breast, pancreas and stomach were performed. FNA cytology and biopsy findings showed papillary carcinoma of the thyroid, invasive ductal adenocarcinoma of the breast, adenocarcinoma of the pancreas and gastrointestinal stromal tumor. To the best of our knowledge, this combination of synchronous multiple primary tumors has not been reported.
authors: Department of Internal Medicine, Chonnam National University Medical School, 8 Hak-Dong, Dong-ku, Gwangju, 501-757, Korea.
authors: Jong-Sun
authors: JS
authors: Kim
authors: Cho-Yun
authors: CY
authors: Chung
authors: Hyung-Chul
authors: HC
authors: Park
authors: Dae-Seong
authors: DS
authors: Myung
authors: Sung-Bum
authors: SB
authors: Cho
authors: Wan-Sik
authors: WS
authors: Lee
authors: Jung-Joon
authors: JJ
authors: Min
authors: Young-Eun
authors: YE
authors: Joo
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000188:drug therapy; D000368:Aged; D044963:Biopsy, Fine-Needle; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000188:drug therapy; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000188:drug therapy; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D049268:Positron-Emission Tomography; D011379:Prognosis; D019275:Radiopharmaceuticals; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: Synchronous cancer; breast; pancreas; stomach; thyroid