title: [Application of computational fluid dynamics in hemodynamic research of aortic arch].
abstract: OBJECTIVE
  To evaluate the application of computational fluid dynamics (CFD) on a patient-specific hemodynamic model of aortic arch.
  
  
  METHODS
  The original Dicom format image data of a patient were acquired by computed tomographic angiography (CTA). A 3-dimensional (3D) model based on CFD was constructed through the right amount of boundary conditions and hemodynamic parameters related with flow velocity, shear force and wall stress on lumen were analyzed accordingly.
  
  
  RESULTS
  The 3D model based on CFD could reflect the characteristic of flow velocity, shear force and wall stress on lumen in vitro. (1) The distributions of hemodynamic variables during cardiac cycle were spatiotemporally different. The unidirectional high-speed systolic current was replaced by diastolic eddy current and reversed flow. The distribution of flow velocity and shear stress gradually increased from outer wall of aortic artery to inner wall under the influences of such anatomical factors as vascular branching and distortions of descending aorta; (2) the magnitude and volatility of wall stress in ascending aorta were greater than those of aortic arch and descending aorta, but the least results were at the lateral wall of descending aorta area. In addition, the wall stress of external wall was higher than the lateral wall in the same section.
  
  
  CONCLUSIONS
  The hemodynamic research of aortic arch based on CFD may actually simulate the characteristics of blood flow and wall stress so as to become a new reliable and convenient application tool in etiological diagnosis and surgical planning.
authors: Department of Vascular Surgery & General Hospital of People's Liberation Army, Beijing, China.
authors: Tao
authors: T
authors: Zhang
authors: Jiang
authors: J
authors: Xiong
authors: Xiao-zhong
authors: XZ
authors: Hu
authors: Xin
authors: X
authors: Jia
authors: Shao-liang
authors: SL
authors: Luan
authors: Wei
authors: W
authors: Guo
mesh_terms: D000790:Angiocardiography / Q000379:methods*; D001013:Aorta, Thoracic / Q000502:physiology*; D003198:Computer Simulation; D006439:Hemodynamics; D006801:Humans; D057446:Hydrodynamics; D008955:Models, Cardiovascular; D014057:Tomography, X-Ray Computed