title: In vivo evaluation of CaO-SiO2-P2O5-B2O3 glass-ceramics coating on Steinman pins.
abstract: Surface coating using ceramics improves the bone bonding strength of an implant. We questioned whether a new type of glass-ceramics (BGS-7) coating (CaO-SiO2 -P2 O5 -B2 O3 ) would improve the osseointegration of Steinman pins (S-pins) both biomechanically and histomorphometrically. An in vivo study was performed using rabbits by inserting three S-pins into each iliac bone. The pins were 2.2-mm S-pins with a coating of 30-μm-thick BGS-7 and 550-nm-thick hydroxyapatite (HA), as opposed to an S-pin without coating. A tensile strength test and histomorphometrical evaluation was performed. In the 2-week group, the BGS-7 implant showed a significantly higher tensile strength than the S-pin. In the 4- and 8-week groups, the BGS-7 implants had significantly higher tensile strengths than the S-pins and HA implants. The histomorphometrical study revealed that the BGS-7 implant had a significantly higher contact ratio than the S-pin and HA implants in the 4-week group. The biomechanical and histomorphometrical tests showed that the BGS-7 coating had superior bone bonding properties than the groups without the coating from the initial stage of insertion. The BGS-7 coating of an S-pin will enhance the bone bonding strength, and there might also be an advantage in human bone bonding.
authors: Department of Orthopedic Surgery, College of Medicine, Seoul National University, SMG-SNU Boramae Medical Center; Institute of Medical and Biological Engineering, Seoul National University, Medical Research Center.
authors: Jae Hyup
authors: JH
authors: Lee
authors: Kug Sun
authors: KS
authors: Hong
authors: Hae-Ri
authors: HR
authors: Baek
authors: Jun-Hyuk
authors: JH
authors: Seo
authors: Kyung Mee
authors: KM
authors: Lee
authors: Hyun-Seung
authors: HS
authors: Ryu
authors: Hyun-Kyung
authors: HK
authors: Lee
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001858:Bone Nails; D002516:Ceramics / Q000737:chemistry*; D020099:Coated Materials, Biocompatible; D017886:Durapatite / Q000737:chemistry; D005898:Glass / Q000737:chemistry*; D007085:Ilium / Q000473:pathology / Q000601:surgery*; D008297:Male; D016348:Osseointegration; D011474:Prosthesis Design; D011817:Rabbits; D013499:Surface Properties; D013718:Tensile Strength; D013997:Time Factors
chemical_list: C584244:CaO-SiO2-P2O5-B2O3 glass; D020099:Coated Materials, Biocompatible; C023506:Glass ceramics; D017886:Durapatite
keywords: CaO-SiO2-P2O5-B2O3 glass ceramics; In vivo study; Osseointegration; Osteoconductivity