title: Community-based cardiovascular Risk Factors Intervention Strategies (CORFIS) in managing hypertension: A pragmatic non-randomised controlled trial.
abstract: BACKGROUND
  Hypertension is the number one cardiovascular risk factor in Malaysia. This study aimed to evaluate the effectiveness of a Community-Based Cardiovascular Risk Factors Intervention Strategies (CORFIS) in the management of hypertension in primary care.
  
  
  METHODS
  This is a pragmatic, non-randomized controlled trial. Seventy general practitioners (GPs) were selected to provide either CORFIS (44 GPs) or conventional care (26 GPs) for 6 months. A total of 486 hypertensive patients were recruited; 309 were in the intervention and 177 in the control groups. Primary outcome was the proportion of hypertensive patients who achieved target blood pressure (BP) of <140/90mmHg (for those without diabetes mellitus) and <130/80mmHg (with diabetes mellitus). Secondary outcomes include change in the mean/median BP at 6-month as compared to baseline.
  
  
  RESULTS
  The proportion of hypertensive patients who achieved target BP at 6-month was significantly higher in the CORFIS arm (69.6%) as compared to the control arm (57.6%), P=0.008. Amongst those who had uncontrolled BP at baseline, the proportion who achieved target BP at 6-month was also significantly higher in the CORFIS arm (56.6%) as compared to the control arm (34.1%), p<0.001. There was no difference in the patients who had already achieved BP control at baseline. There were significant reductions in SBP in the CORFIS arm (median -9.0mmHg; -60 to 50) versus control (median -2mmHg; -50 to 48), p=0.003; as well as in DBP (CORFIS arm: median -6.0mmHg; ranged from -53 to 30 versus control arm: median 0.0mmHg; ranged from -42 to 30), p<0.001.
  
  
  CONCLUSIONS
  Patients who received CORFIS care demonstrated significant improvements in achieving target BP.
authors: Clinical Research Center, Clinical Epidemiology Unit, 1st Floor MMA House, 124, Jalan Pahang, Kuala Lumpur 53000 Malaysia. wymenseet@gmail.com.
authors: W H H
authors: WH
authors: Low
authors: W
authors: W
authors: Seet
authors: Ramli
authors: R
authors: A S
authors: K K
authors: KK
authors: Ng
authors: Jamaiyah
authors: J
authors: H
authors: S P
authors: SP
authors: Dan
authors: C L
authors: CL
authors: Teng
authors: V K M
authors: VK
authors: Lee
authors: S S
authors: SS
authors: Chua
authors: Faridah Aryani
authors: FA
authors: M Y
authors: Karupaiah
authors: K
authors: T
authors: W S S
authors: WS
authors: Chee
authors: P P
authors: PP
authors: Goh
authors: Zaki
authors: Z
authors: M
authors: T O
authors: TO
authors: Lim
mesh_terms: D001794:Blood Pressure; D002318:Cardiovascular Diseases; D003920:Diabetes Mellitus; D006801:Humans; D006973:Hypertension; D012307:Risk Factors