title: Whole genome sequencing in the undergraduate classroom: outcomes and lessons from a pilot course.
abstract: The BIO2010 report challenged undergraduate institutions to prepare the next generation of researchers for the changing direction of biology that increasingly integrates advanced technologies, digital information, and large-scale analyses. In response, the Microbiology and Cell Science Department at the University of Florida developed a research-based course, "Bacterial Genome Sequencing." The objectives were to teach undergraduates about genomics and original research by sequencing a bacterial genome, to develop scientific communication skills by writing and submitting the project results as a class effort, and to promote an interest in biological research, particularly genomics. The students worked together to sequence, assemble, and annotate the Enterobacter cloacae P101 genome. We assessed student learning, scientific communication skills, and student attitudes by a variety of methods including exams, writing assignments, oral presentations, pre- and postcourse surveys, and a final exit survey. Assessment results demonstrate student learning gains and positive attitudes regarding the course.
authors: Department of Microbiology and Cell Science, University of Florida, Gainesville, Florida 32611.
authors: Jennifer C
authors: JC
authors: Drew
authors: Eric W
authors: EW
authors: Triplett
references: Cell Biol Educ. 2003 Winter;2(4):233-47
references: 14673489
references: Mutat Res. 2005 Jun 3;573(1-2):13-40
references: 15829235
references: Cell Biol Educ. 2002 Winter;1(4):101-4
references: 12669103
references: Cell Biol Educ. 2005 Summer;4(2):143-56
references: 15917873
references: CBE Life Sci Educ. 2006 Spring;5(1):52-64
references: 17012191
references: Nature. 2005 Sep 15;437(7057):376-80
references: 16056220
references: Cell Biol Educ. 2005 Winter;4(4):291-7
references: 16341256
references: Cell Biol Educ. 2005 Fall;4(3):249-60
references: 16220145
references: PLoS Biol. 2005 Feb;3(2):e59
references: 15719063
references: Nucleic Acids Res. 2005 Oct 07;33(17):5691-702
references: 16214803
references: Int J Dev Biol. 2003;47(2-3):135-40
references: 12705660
references: Microbiol Educ. 2002 May;3:18-25
references: 23653546
references: Int J Dev Biol. 2003;47(2-3):213-21
references: 12705672
references: Microbiol Educ. 2004 May;5:3-12
references: 23653552
references: Microbiol Educ. 2004 May;5:30-5
references: 23653555
references: Cell Biol Educ. 2003 Summer;2(2):98-111
references: 12888845
references: Curr Opin Microbiol. 2005 Oct;8(5):564-71
references: 16125442
references: Science. 2004 Apr 23;304(5670):521-2
references: 15105480
references: Science. 1995 Jul 28;269(5223):496-512
references: 7542800
references: Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W455-9
references: 15980511
references: Cell Biol Educ. 2002 Aug 08;1(3):70-2
references: 12459791