title: Severe acute post-streptococcal glomerulonephritis in an infant.
abstract: Acute post-streptococcal glomerulonephritis (APSGN) is very rare below the age of two years. We report a 14-month-old girl who presented with frank hematuria and nephrotic syndrome following group A streptococcal pharyngitis (GAS), which was confirmed by laboratory investigations. The patient underwent a renal biopsy to confirm the diagnosis and was treated with prednisolone. The proteinuria and hematuria resolved completely in eight weeks. Our case demonstrates that APSGN should be considered in evaluating hematuria and nephrotic syndrome in infants and children below two years of age.
authors: Department of Pediatrics, King Abdulaziz University Hospital, Jeddah, Saudi Arabia. jkari@doctors.org.uk
authors: Jameela A
authors: JA
authors: Kari
authors: Ahmed
authors: A
authors: Bamagai
authors: Sawsan M
authors: SM
authors: Jalalah
mesh_terms: D000208:Acute Disease; D001706:Biopsy; D005260:Female; D005921:Glomerulonephritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005938:Glucocorticoids / Q000627:therapeutic use; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007223:Infant; D007668:Kidney / Q000473:pathology* / Q000648:ultrastructure; D046529:Microscopy, Electron, Transmission; D009404:Nephrotic Syndrome / Q000209:etiology; D010612:Pharyngitis / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D011239:Prednisolone / Q000627:therapeutic use; D012720:Severity of Illness Index; D013290:Streptococcal Infections / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone