title: Organobase-catalyzed amidation of esters with amino alcohols.
abstract: A base-mediated procedure for the amidation of unactivated esters with amino alcohols is reported. Optimization and exemplification of the catalytic process are described, furnishing products in 40-100% isolated yield.
authors: Department of Pure and Applied Chemistry, University of Strathclyde , 295 Cathedral Street, Glasgow, G1 1XL, U.K., and AstraZeneca , Oncology Innovative Medicines Unit, Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K.
authors: Nicola
authors: N
authors: Caldwell
authors: Craig
authors: C
authors: Jamieson
authors: Iain
authors: I
authors: Simpson
authors: Tell
authors: T
authors: Tuttle
mesh_terms: D000577:Amides / Q000737:chemistry*; D000605:Amino Alcohols / Q000737:chemistry*; D002384:Catalysis; D004952:Esters; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000577:Amides; D000605:Amino Alcohols; D004952:Esters