title: [Predictors of the closure of tuberculosis infiltrate decay cavities during the conservative treatment of infiltrative tuberculosis].
abstract: We studied predictors of the closure of tuberculosis infiltrate decay cavities (DC) in the affected regions in patients with infiltrative lung tuberculosis (ILT) by clinical examination. X-ray laboratory and psychological methods 103 patients were under observation for 12 months and received standard therapy. The closure was achieved during the first 4 months in 74 patients but did not occur in 29 ones. Logistic regression analysis showed that the probability of DC closure in the first 4 months decreases in parallel to the initial character of complaints of "chest pain", the size of tuberculosis infiltrates determined in X-ray study, results of thymol test, content of lipid peroxides in expirates, depressive "fatigue" and "suicidal thoughts". The probability of DC cavity during 4 months increased with the initial "number of destructions" in the infiltrate (by X-ray) and depressive "loss of working ability". Results of regression analysis permit to predict the closure of DC during the first 4 months with sensitivity 98.3% and specificity 82.4%.
authors: I A
authors: IA
authors: Volchegorskiĭ
authors: P N
authors: PN
authors: Novoselov
authors: T P
authors: TP
authors: Dudarova
authors: A A
authors: AA
authors: Bolotov
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D011237:Predictive Value of Tests; D012044:Regression Analysis; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology / Q000523:psychology
chemical_list: D000995:Antitubercular Agents