title: A sensitive method for the determination of levamisole in serum by electrochemiluminescence.
abstract: A novel method was developed for the determination of levamisole by electrochemiluminescence. The method was based on electrochemiluminescence signal enhancement produced by Ru(bpy)(3)(2+), which reacted with the tertiary amine group of levamisole on a platinum electrode in 12 mmol/L borate buffer (pH 9). A linear relationship between the luminous intensity and concentration of levamisole in the range 0-1 × 10(-7) mol/L was obtained and the detection limit was 1.76 × 10(-11) mol/L. The method is sensitive, selective, simple and convenient. The method has been successfully applied to the analysis of levamisole in serum.
authors: College of Chemistry and Bioengineering, Guilin University of Technology, Guilin, Guangxi, 541004, China.
authors: Ying
authors: Y
authors: Xiao
authors: Jianping
authors: J
authors: Li
authors: Cong
authors: C
authors: Fu
mesh_terms: D055664:Electrochemical Techniques; D006801:Humans; D007978:Levamisole / Q000097:blood* / Q000737:chemistry; D008163:Luminescent Measurements; D015394:Molecular Structure
chemical_list: D007978:Levamisole
keywords: Electrochemiluminescence; Levamisole; Ru(bpy)32+