title: Assessing the quality of VA Human Research Protection Programs: VA vs. affiliated University Institutional Review Board.
abstract: We compared the Human Research Protection Program (HRPP) quality indicator data of the Department of Veterans Affairs (VA) facilities using their own VA institutional review boards (IRBs) with those using affiliated university IRBs. From a total of 25 performance metrics, 13 did not demonstrate statistically significant differences, while 12 reached statistically significance differences. Among the 12 with statistically significant differences, facilities using their own VA IRBs performed better on four of the metrics, while facilities using affiliate IRBs performed better on eight. However, the absolute difference was small (0.2-2.7%) in all instances, suggesting that they were of no practical significance. We conclude that it is acceptable for facilities to use their own VA IRBs or affiliated university IRBs as their IRBs of record.
authors: Office of Research Oversight, Department of Veterans Affairs, N W Washington, DC 20240, USA. min-fu.tsan2@va.gov
authors: Min-Fu
authors: MF
authors: Tsan
authors: Yen
authors: Y
authors: Nguyen
authors: Robert
authors: R
authors: Brooks
mesh_terms: D028744:Ethics Committees, Research / Q000592:standards*; D006801:Humans; D009935:Organizational Affiliation; D014481:United States; D014493:United States Department of Veterans Affairs / Q000941:ethics*; D014495:Universities / Q000941:ethics*