title: Perioperative management of bridge-to-lung transplant using ECMO.
abstract: Respiratory failure requiring intubation has traditionally been a relative contraindication to lung transplantation due to increased morbidity and mortality. Advances in extracorporeal membranous oxygenation (ECMO) have made it possible to extubate patients and provide physical therapy with minimal native lung function. By "bridging" patients to lung transplant using ECMO, they are able to undergo rehabilitation and withstand the demands of surgery. However, providing anesthesia for these cases requires an understanding of ECMO physiology and the pharmacology associated with ECMO. We describe the anesthetic for four patients who were bridged to lung transplant and the complexities of their perioperative management.
authors: Department of Anesthesiology, University of Michigan Health System, Ann Arbor, Michigan 48109-5861, USA. jmblum@umich.edu
authors: James M
authors: JM
authors: Blum
authors: Brian J
authors: BJ
authors: Woodcock
authors: Anna V
authors: AV
authors: Dubovoy
authors: Timur
authors: T
authors: Dubovoy
authors: Muhammad
authors: M
authors: Masood
authors: Andrew C
authors: AC
authors: Chang
authors: Jules
authors: J
authors: Lin
authors: Jonathan W
authors: JW
authors: Haft
mesh_terms: D000328:Adult; D015199:Extracorporeal Membrane Oxygenation / Q000379:methods*; D006801:Humans; D016040:Lung Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D019990:Perioperative Care / Q000379:methods*; D012131:Respiratory Insufficiency / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D016896:Treatment Outcome