title: Mammotome biopsy in diagnosing and treatment of intraductal papilloma of the breast.
abstract: Intraductal papilloma is a benign breast tumor which needs histopathological verification because of the risk of cancer coincidence.
  
  
  OBJECTIVE
  To assess the value of the mammography-guided and ultrasound-guided vacuum-assisted core biopsy in the diagnosis and treatment of intraductal papillomas of breast and to answer the question if mammotome biopsy allows to avoid surgery in these patients.
  
  
  METHODS
  In the period 2000-2011, a total of 2246 vacuum-assisted core biopsies were performed, of which 1495 were ultrasound-guided and 751 were mammography-guided (stereotaxic). In 76/2246 patients (3.4%), aged 19-88 years (mean age was 51,5) histopathological examination confirmed intraductal papilloma.
  
  
  RESULTS
  Atypical lesions were accompanying intraductal papilloma in 16/76 cases (21%). Open surgical biopsy performed in these group revealed invasive cancer in 3 women. In all 60 cases (79%) with benign papilloma in biopsy specimens, further clinical observation did not show recurrence or malignant transformation of lesions.
  
  
  CONCLUSIONS
  Vacuum-assisted core biopsy is a minimally invasive and efficient method used for diagnosing intraductal papilloma of the breast. If histopathological examination confirms a benign character of the lesion, surgery may be avoided but regular follow-up is recommended. However, in all cases histopathological diagnosis of papilloma with atypical hyperplasia, should always be indication for surgical excision.
authors: Wojciech
authors: W
authors: Kibil
authors: Diana
authors: D
authors: Hodorowicz-Zaniewska
authors: Tadeusz J
authors: TJ
authors: Popiela
authors: Joanna
authors: J
authors: Szpor
authors: Jan
authors: J
authors: Kulig
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D005260:Female; D006801:Humans; D061705:Image-Guided Biopsy; D008327:Mammography; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology; D018300:Papilloma, Intraductal / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy*; D016217:Ultrasonography, Mammary; D055815:Young Adult