title: Insight to neoplastic thyroid lesions by fine needle aspiration cytology.
abstract: BACKGROUND
  Fine needle aspiration cytology (FNAC) is a valuable adjunct to pre-operative screening in the diagnosis of thyroid nodules, and in most cases, it can distinguish between benign and malignant lesions.
  
  
  OBJECTIVE
  To study the cytology of neoplastic thyroid lesions to minimize surgical intervention and for confirmation of the diagnosis by histopathological study.
  
  
  METHODS
  100 cases of thyroid FNAC smears were analyzed and cyto-histopathological correlation was done in 47 cases. Galen and Gambino's method was used to calculate the sensitivity and positive predictive value.
  
  
  RESULTS
  Of the 100 cases, 90 were diagnosed as neoplastic lesions by FNAC and ten cases as non-neoplastic lesions, which turned out to be neoplasms on histopathological study. Among 100 cases, 47 were biopsied and subjected to histopathological study. The sensitivity of FNAC was 75.60%, and positive predictive value was 83.78% for malignant lesions.
  
  
  CONCLUSIONS
  FNAC is a rapid, efficient, cost-effective, relatively painless procedure with a high diagnostic accuracy. It has high rate of sensitivity and positive predictive value in diagnosing thyroid neoplastic lesions. Hence, it is a valuable tool in the diagnosis and management of patients.
authors: Department of Pathology, JSS Medical College and Hospital, JSS University, Mysore, Karnataka, India.
authors: M
authors: M
authors: Rangaswamy
authors: Kl
authors: K
authors: Narendra
authors: S
authors: S
authors: Patel
authors: C
authors: C
authors: Gururajprasad
authors: Gv
authors: G
authors: Manjunath
keywords: Cyto-histopathological correlation; fine needle aspiration cytology; thyroid lesions
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