title: Lack of serum antibodies against Borrelia burgdorferi in children with autism.
abstract: It has been proposed that Borrelia burgdorferi infection is present in ∼25% of children with autism spectrum disorders. In this study, antibodies against Borrelia burgdorferi were assessed in autistic (n = 104), developmentally delayed (n = 24), and healthy control (n = 55) children. No seropositivity against Borrelia burgdorferi was detected in the children with and without autism. There was no evidence of an association between Lyme disease and autism.
authors: Neurobiology and Pain Therapeutics Section, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, USA. burbelop@nidcr.nih.gov
authors: Peter D
authors: PD
authors: Burbelo
authors: Susan E
authors: SE
authors: Swedo
authors: Audrey
authors: A
authors: Thurm
authors: Ahmad
authors: A
authors: Bayat
authors: Andrew E
authors: AE
authors: Levin
authors: Adriana
authors: A
authors: Marques
authors: Michael J
authors: MJ
authors: Iadarola
mesh_terms: D000907:Antibodies, Bacterial / Q000097:blood*; D001321:Autistic Disorder / Q000150:complications*; D025065:Borrelia burgdorferi / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007223:Infant; D008193:Lyme Disease / Q000453:epidemiology* / Q000276:immunology; D008297:Male; D016036:Seroepidemiologic Studies; D044967:Serum / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial
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