title: Phylogenetic examination of crude drugs derived from Yunnanese Swertia plants.
abstract: Aiming to examine whether the genetic background of the crude drugs derived from four Yunnanese Swertia plants and their chemical constituent profiles correlate, we analyzed the nucleotide sequences of their nuclear ribosomal DNA regions including ITS1, 5.8S ribosomal RNA gene, and ITS2, together with those of Japanese S. japonica and S. pseudochinensis from Hebei Province. The result that two of the Yunnanese Swertia plants, S. binchuanensis and S. punicea, were genetically similar may explain their similarity in chemical constituent profiles. On the other hand, in spite of differences in chemical profile, S. decora and S. pseudochinensis were genetically close. The other Yunnanese Swertia plants, S. delavayi, and S. japonica, stood at intermediate positions between these two genetically similar pairs. The result suggests that although genetic background would have an influence, environmental factors, e.g., soil and weather conditions, might be critical for their production of secondary metabolites.
authors: School of Pharmaceutical Sciences, Kyusyu University of Health and Welfare, 1714-1 Yoshino-cho, Nobeoka, Miyazaki, 882-8508, Japan, kakiuchi@phoenix.ac.jp.
authors: Nobuko
authors: N
authors: Kakiuchi
authors: Naoko
authors: N
authors: Iwaki
authors: Masayuki
authors: M
authors: Mikage
authors: Huai
authors: H
authors: Xiao
authors: Zhigang
authors: Z
authors: Wang
authors: Masao
authors: M
authors: Hattori
mesh_terms: D058893:DNA Barcoding, Taxonomic; D018744:DNA, Plant / Q000032:analysis*; D004275:DNA, Ribosomal / Q000032:analysis*; D059647:Gene-Environment Interaction; D010802:Phylogeny; D008517:Phytotherapy; D028321:Plant Preparations / Q000032:analysis*; D010946:Plants, Medicinal; D021521:Ribotyping; D013045:Species Specificity; D029967:Swertia / Q000737:chemistry / Q000145:classification / Q000235:genetics*
chemical_list: D018744:DNA, Plant; D004275:DNA, Ribosomal; D028321:Plant Preparations
references: Chem Pharm Bull (Tokyo). 1997 Nov;45(11):1823-7
references: 9396160
references: Planta Med. 1994 Dec;60(6):507-11
references: 7809201
references: Chem Pharm Bull (Tokyo). 2008 Apr;56(4):485-90
references: 18379095
references: Planta Med. 2006 Oct;72(13):1223-6
references: 17051455
references: J Ethnopharmacol. 1991 May-Jun;33(1-2):31-5
references: 1943170
references: Yao Xue Xue Bao. 2001 Jan;36(1):67-70
references: 12579865