title: The effects and outcomes of electrolyte disturbances and asphyxia on newborns hearing.
abstract: OBJECTIVE
  To determine the effect of electrolyte disturbances (ED) and asphyxia on infant hearing and hearing outcomes.
  
  
  METHODS
  We conducted newborn hearing screening with transient evoked otoacoustic emission (TEOAE) test on a large scale (>5000 infants). The effects of ED and asphyxia on infant hearing and hearing outcomes were evaluated.
  
  
  RESULTS
  The pass rate of TEOAE test was significantly reduced in preterm infants with ED (83.1%, multiple logistic regression analysis: P<0.01) but not in full-term infants with ED (93.6%, P=0.41). However, there was no significant reduction in the pass rate in infants with asphyxia (P=0.85). We further found that hypocalcaemia significantly reduced the pass rate of TEOAE test (86.8%, P<0.01). In the follow-up recheck at 3 months of age, the pass rate remained low (44.4%, P<0.01).
  
  
  CONCLUSIONS
  ED is a high-risk factor for preterm infant hearing. Hypocalcaemia can produce more significant impairment with a low recovery rate.
authors: Maternal and Child Health Care Hospital of Baoan, Shenzhen 518133, PR China.
authors: Chun
authors: C
authors: Liang
authors: Qi
authors: Q
authors: Hong
authors: Tao-Tao
authors: TT
authors: Jiang
authors: Yan
authors: Y
authors: Gao
authors: Xiao-Fang
authors: XF
authors: Yao
authors: Xiao-Xing
authors: XX
authors: Luo
authors: Xiu-Hui
authors: XH
authors: Zhuo
authors: Jennifer B
authors: JB
authors: Shinn
authors: Raleigh O
authors: RO
authors: Jones
authors: Hong-Bo
authors: HB
authors: Zhao
authors: Guang-Jin
authors: GJ
authors: Lu
mesh_terms: D001237:Asphyxia / Q000150:complications*; D002681:China; D005260:Female; D006311:Hearing Disorders / Q000175:diagnosis / Q000209:etiology*; D006320:Hearing Tests; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D016015:Logistic Models; D008297:Male; D015997:Neonatal Screening / Q000379:methods*; D017084:Otoacoustic Emissions, Spontaneous; D012307:Risk Factors; D014883:Water-Electrolyte Imbalance / Q000150:complications*
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