title: Engineering the soil bacterium Pseudomonas putida for arsenic methylation.
abstract: Accumulation of arsenic has potential health risks through consumption of food. Here, we inserted the arsenite [As(III)] S-adenosylmethionine methyltransferase (ArsM) gene into the chromosome of Pseudomonas putida KT2440. Recombinant bacteria methylate inorganic arsenic into less toxic organoarsenicals. This has the potential for bioremediation of environmental arsenic and reducing arsenic contamination in food.
authors: Department of Cellular Biology and Pharmacology, Florida International University, Herbert Wertheim College of Medicine, Miami, Florida, USA.
authors: Jian
authors: J
authors: Chen
authors: Jie
authors: J
authors: Qin
authors: Yong-Guan
authors: YG
authors: Zhu
authors: Víctor
authors: V
authors: de Lorenzo
authors: Barry P
authors: BP
authors: Rosen
mesh_terms: D020418:Algal Proteins / Q000235:genetics / Q000378:metabolism; D001151:Arsenic / Q000378:metabolism*; D001673:Biodegradation, Environmental; D016825:Chlamydomonas reinhardtii / Q000235:genetics; D002851:Chromatography, High Pressure Liquid; D004591:Electrophoresis, Polyacrylamide Gel; D052918:Environmental Restoration and Remediation / Q000379:methods*; D013058:Mass Spectrometry; D008745:Methylation; D008780:Methyltransferases / Q000235:genetics* / Q000378:metabolism; D030781:Organisms, Genetically Modified / Q000235:genetics / Q000378:metabolism; D016133:Polymerase Chain Reaction; D016958:Pseudomonas putida / Q000235:genetics* / Q000378:metabolism*; D012989:Soil Pollutants / Q000378:metabolism*
chemical_list: D020418:Algal Proteins; D012989:Soil Pollutants; D008780:Methyltransferases; D001151:Arsenic
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