title: The potential harm of oxygen therapy in medical emergencies.
abstract: In medical emergencies, supplemental oxygen is often administrated routinely. Most paramedics and physicians believe that high concentrations of oxygen are life-saving 1. Over the last century, however, a plethora of studies point to possible detrimental effects of hyperoxia induced by supplemental oxygen in a variety of medical emergencies. This viewpoint provides a historical overview and questions the safety of routine high-dose oxygen administration and is based on pathophysiology and (pre)clinical findings in various medical emergencies.
authors: Alexander D
authors: AD
authors: Cornet
authors: Albertus J
authors: AJ
authors: Kooter
authors: Mike J L
authors: MJ
authors: Peters
authors: Yvo M
authors: YM
authors: Smulders
mesh_terms: D002986:Clinical Trials as Topic / Q000379:methods; D004630:Emergencies; D004632:Emergency Medical Services / Q000379:methods* / Q000592:standards; D006801:Humans; D010102:Oxygen Inhalation Therapy / Q000009:adverse effects* / Q000379:methods*
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