title: Arthropathy, osteolysis, keloids, relapsing conjunctival pannus and gingival overgrowth: a variant of polyfibromatosis?
abstract: Polyfibromatosis is a rare fibrosing condition characterized by fibromatosis in different body areas and by keloid formation, and which can be associated with arthropathy and osteolysis. Familial occurrence has been described, but the cause remains unknown. Here, we describe a patient with characteristics of polyfibromatosis with arthropathy who had in addition severe conjunctival fibrosis, distinctive face, gingival overgrowth, and pigmented keloids. We discuss the resemblances and differences with polyfibromatosis and descriptions of other, similar patients. We conclude that at present it remains uncertain whether the patient has a variant of polyfibromatosis or a separate entity.
authors: Section of Dermatology, Department of Health Sciences, University of Genoa, and Unit of Radiology, Galliera Hospital, Genoa, Italy. elisacinotti@gmail.com
authors: Elisa
authors: E
authors: Cinotti
authors: Giulio
authors: G
authors: Ferrero
authors: Francesco
authors: F
authors: Paparo
authors: Marina
authors: M
authors: Papadia
authors: Francesca
authors: F
authors: Faravelli
authors: Franco
authors: F
authors: Rongioletti
authors: Carlo
authors: C
authors: Traverso
authors: Emilio
authors: E
authors: Di Maria
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D001175:Arthrography; D002972:Cleft Palate / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D055028:Comparative Genomic Hybridization; D003229:Conjunctival Diseases / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology*; D003286:Contracture / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D020732:Cytogenetic Analysis; D003937:Diagnosis, Differential; D005350:Fibroma / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology*; D005351:Fibromatosis, Gingival / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology*; D005355:Fibrosis / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D033023:Foot Joints / Q000000981:diagnostic imaging / Q000473:pathology; D019214:Gingival Overgrowth / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D050823:Hand Joints / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D007592:Joint Diseases / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology*; D007627:Keloid / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D017880:Limb Deformities, Congenital / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000000981:diagnostic imaging / Q000235:genetics / Q000473:pathology*