title: The uveitis and its relationship with disease activity and quality of life in Moroccan children with juvenile idiopathic arthritis.
abstract: The aim of our study is to investigate ocular involvement in juvenile idiopathic arthritis (JIA) and its relationship with disease activity and quality of life in Moroccan patients who suffer from JIA. This is a cross-sectional study conducted between January and June 2012 which includes patients with juvenile idiopathic arthritis (n = 30). All patients have undergone clinical and paraclinical assessment of JIA and a complete eye examination. Functional impairment is assessed by the Childhood Health Assessment Questionnaire while visual function is studied by the Effect of Youngsters' Eyesight in Quality of Life instrument (EYE-Q). Quality of life is assessed using the Pediatric Quality of Life Inventory Version 4.0 (PedsQL 4.0). Four patients (13.33 %) have uveitis with a confidence interval between 3.4 and 30.7. Involvement is bilateral in three children (75 %). One patient (25 %) has elevated intraocular pressure with loss of the right eye due to glaucoma. There is a strong but not significant relationship between uveitis and the number of awakenings (r = 0.71, p = 0.69) and morning stiffness (r = 3.05, p = 0, 21). This relationship is moderate with erythrocyte sedimentation rate (r = 0.48, p = 0.78) and C-reactive protein (r = 0.25, p = 0.88). A strong but not significant association is found between the overall quality of life assessed by the PedsQL 4.0 and visual function assessed by EYE-Q in the uveitis group (r = -0.64, p = 0.55). This study suggests that uveitis associated with JIA can present serious complications and could have a direct relationship with the activity of the JIA as well as with the quality of life of the patient.
authors: LIRPOS-URAC30, Service de rhumatologie, Hôpital El Ayachi, CHU Rabat-Salé, Université Mohammed V Souissi, Rabat, Morocco. majdaezzahri@hotmail.com
authors: M
authors: M
authors: Ezzahri
authors: B
authors: B
authors: Amine
authors: S
authors: S
authors: Rostom
authors: Y
authors: Y
authors: Rifay
authors: D
authors: D
authors: Badri
authors: N
authors: N
authors: Mawani
authors: S
authors: S
authors: Gueddari
authors: S
authors: S
authors: Shyen
authors: M
authors: M
authors: Wabi
authors: F
authors: F
authors: Moussa
authors: R
authors: R
authors: Abouqal
authors: B
authors: B
authors: Chkirate
authors: N
authors: N
authors: Hajjaj-Hassouni
mesh_terms: D000293:Adolescent; D001171:Arthritis, Juvenile / Q000150:complications* / Q000523:psychology*; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000378:metabolism; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D009018:Morocco; D011379:Prognosis; D011788:Quality of Life; D011795:Surveys and Questionnaires; D014605:Uveitis / Q000150:complications* / Q000175:diagnosis / Q000523:psychology*; D014785:Vision, Ocular; D014792:Visual Acuity
chemical_list: D002097:C-Reactive Protein
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