title: Nutritional factors, physical activity, and breast cancer by hormonal receptor status.
abstract: OBJECTIVE
  To investigate the association between food and nutrient intake, occupational and leisure-time physical activity, and body mass index and breast cancer risk by estrogen receptor (ER) and progesterone receptor (PR) status.
  
  
  METHODS
  We analyzed data from a hospital-based case-control study conducted between 1991 and 1994 in Italy, including 1075 women with incident breast cancer and 1477 controls.
  
  
  RESULTS
  The associations with breast cancer risk were similar according to ER status for all risk factors considered. In particular, significant reduced risk of ER- and ER+ breast cancers were observed for raw vegetables (multivariate odds ratio, OR, for high vs low consumption: 0.6 and 0.7, respectively) and for polyunsaturated fats (OR: 0.6 and 0.7, respectively). No significant heterogeneous risk estimates were observed for combinations of ER and PR status.
  
  
  CONCLUSIONS
  Our study does not suggest major differences risk for various dietary and lifestyle factors according to ER and PR breast cancer subtypes.
authors: Department of Epidemiology, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Via Giuseppe La Masa 19, 20156 Milan, Italy; Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy.
authors: Valentina
authors: V
authors: Rosato
authors: Paola
authors: P
authors: Bertuccio
authors: Cristina
authors: C
authors: Bosetti
authors: Eva
authors: E
authors: Negri
authors: Valeria
authors: V
authors: Edefonti
authors: Monica
authors: M
authors: Ferraroni
authors: Adriano
authors: A
authors: Decarli
authors: Renato
authors: R
authors: Talamini
authors: Luigino
authors: L
authors: Dal Maso
authors: Fabio
authors: F
authors: Falcini
authors: Maurizio
authors: M
authors: Montella
authors: Silvia
authors: S
authors: Franceschi
authors: Carlo
authors: C
authors: La Vecchia
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D015992:Body Mass Index; D001943:Breast Neoplasms / Q000737:chemistry* / Q000453:epidemiology*; D016022:Case-Control Studies; D004032:Diet; D005231:Fatty Acids, Unsaturated; D005260:Female; D005492:Folic Acid; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008461:Meat Products; D008875:Middle Aged; D009043:Motor Activity; D011200:Poultry; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*; D012307:Risk Factors; D014675:Vegetables; D014807:Vitamin D; D014810:Vitamin E; D019207:beta Carotene
chemical_list: D005231:Fatty Acids, Unsaturated; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D019207:beta Carotene; D014807:Vitamin D; D014810:Vitamin E; D005492:Folic Acid
keywords: Breast cancer; Case–control study; Hormonal receptor status; Nutritional factors; Physical activity