title: Clinico- pathological profile of patients with breast diseases.
abstract: BACKGROUND
  To evaluate the spectrum of breast diseases and their association with presenting complains of patients.
  
  
  METHODS
  It was a cross sectional study conducted from 1st January 2010 - 30th December 2012. A total of 254 breast specimens of patients, who were admitted in Civil Hospital Karachi with breast complaints, were included. Specimens were collected either from mastectomy, lumpectomy or needle biopsy from the admitted patients. Informed written consent was taken from all the patients. All patients with primary breast diseases were included. Patients undergoing chemotherapy or with secondary breast disease and slides with insufficient specimen were excluded. All data was entered and analyzed through SPSS 19.
  
  
  RESULTS
  There were 254 breast lesions, histologically diagnosed in 3 year review period. The overall mean age of patients with breast lesion was 25.18, SD ± 11.73 with a wide age range of 12-74 years. Most common cases identified are benign 191(75.3%), followed by inflammatory 30(11.8%) and malignant lesions 30(11.8%). Most patients presenting with the complain of pain have diagnosis of fibroadenoma 24 (63.2%) while patient with complain of lump also have the most common diagnosis of fibroadenoma 147 (72.8%).
  
  
  CONCLUSIONS
  Study shows that in Pakistani females, mostly encountered breast lesion was fibroadenoma. Due to lack of awareness breast diseases present lately. Awareness must be created among women to reduce the mortality and morbidity with breast lesions.
  The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1037059088969395.
authors: Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
authors: Hafiz Muhammad
authors: HM
authors: Aslam
authors: Shafaq
authors: S
authors: Saleem
authors: Hiba Arshad
authors: HA
authors: Shaikh
authors: Nazish
authors: N
authors: Shahid
authors: Anum
authors: A
authors: Mughal
authors: Ribak
authors: R
authors: Umah
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000379:methods; D001941:Breast Diseases / Q000150:complications / Q000453:epidemiology / Q000473:pathology*; D002648:Child; D005260:Female; D018226:Fibroadenoma / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D010154:Pakistan / Q000453:epidemiology; D055815:Young Adult
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