title: Isolated sinusitis sphenoidalis caused by Trichoderma longibrachiatum in an immunocompetent patient with headache.
abstract: We present a case of isolated sinusitis sphenoidalis caused by Trichoderma longibrachiatum, an emerging causal agent of fungal infections with an often fatal outcome. A Trichoderma strain was isolated from secretion obtained from the sinus sphenoidalis of a rhinosinusitis patient and identified by sequence analysis of two loci as Trichoderma longibrachiatum from the Longibrachiatum Clade of the genus Trichoderma. T. longibrachiatum can trigger a fatal pathomechanism in immunodeficient patients, but only rarely causes disease in healthy people. The case presented is unique because the patient was not immunocompromised.
authors: Department of Otorhinolaryngology, Dr. Marron Clinics, Szeged, Hungary.
authors: Etelka
authors: E
authors: Molnár-Gábor
authors: Department of Clinical Microbiology, Albert Szent-Györgyi Clinical Centre, University of Szeged, Szeged, Hungary.
authors: Ilona
authors: I
authors: Dóczi
authors: Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
authors: Lóránt
authors: L
authors: Hatvani
authors: Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
authors: Csaba
authors: C
authors: Vágvölgyi
authors: Department of Microbiology, Faculty of Science and Informatics, University of Szeged, Szeged, Hungary.
authors: László
authors: L
authors: Kredics
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use*; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D005260:Female; D056426:Genetic Loci / Q000235:genetics; D006261:Headache; D006801:Humans; D007121:Immunocompetence; D008279:Magnetic Resonance Imaging; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D017422:Sequence Analysis, DNA; D015524:Sphenoid Sinusitis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014242:Trichoderma / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*
chemical_list: D000935:Antifungal Agents; D004271:DNA, Fungal