title: A highly selective fluorescent sensor for Fe3+ based on covalently immobilized derivative of naphthalimide.
abstract: In this paper, the fabrication and analytical characteristics of fluorescence-based ferric ion-sensing glass slides were described. To fabricate the sensor, a naphthalimide derivative (compound 1) with a terminal double bond was synthesized and copolymerized with 2-hydroxyethyl methacrylate (HEMA) on the activated surface of glass slides by UV irradiation. Upon the addition of Fe(3+) in 0.05 mol/L Tris/HCl (pH 6.02) at 25 °C, the fluorescence intensity of the resulting optical sensor decrease, which has been utilized as the basis for the selective detection of Fe(3+). The sensor can be applied to the quantification of Fe(3+) with a linear range covering form 1.0×10(-5) to 1.0×10(-3) M and a detection limit of 4.5×10(-6) M. The experiment results show that the response behavior of the sensor to Fe(3+) is pH-independent in medium condition (pH 5.00-8.00) and exhibits high selectivity for Fe(3+) over a large number of cations such as alkali, alkaline earth and transitional metal ions. Moreover, satisfactory reproducibility, reversibility and a rapid response were realized. The sensing membrane was found to have a lifetime at least 2 months. The accuracy and the precision of the method were evaluated by the analysis of the standard reference material, iron in water (1.0 mol/L HNO3). The developed sensor is applied for the determination of iron in pharmaceutical preparation samples with satisfactory results.
authors: Department of Dynamical Engineering, North China University of Water Resources and Electric Power, Zhengzhou 450011, PR China.
authors: Jun-Hong
authors: JH
authors: Xu
authors: Yi-Min
authors: YM
authors: Hou
authors: Qiu-Juan
authors: QJ
authors: Ma
authors: Xue-Fen
authors: XF
authors: Wu
authors: Xiao-Jie
authors: XJ
authors: Wei
mesh_terms: D002412:Cations / Q000032:analysis; D005290:Ferric Compounds / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D005898:Glass / Q000737:chemistry*; D057230:Limit of Detection; D008689:Methacrylates / Q000737:chemistry; D053644:Naphthalimides / Q000737:chemistry*; D013050:Spectrometry, Fluorescence / Q000379:methods
chemical_list: D002412:Cations; D005290:Ferric Compounds; D005456:Fluorescent Dyes; D008689:Methacrylates; D053644:Naphthalimides; C005044:hydroxyethyl methacrylate