title: Fluctuation in plasma bone metabolic markers in multiparous and primiparous Holstein cows during early to peak lactation.
abstract: Because the role of bone turnover during early to peak lactation in dairy cows is unclear, plasma levels of osteoclast- or collagen-specific bone resorption and osteoblast-specific bone formation markers from postpartum week 3 (W+3) to W+7 were compared with prepartum W-3 levels in multiparous (n = 15) and primiparous (n = 13) Holstein cows. The multiparous group showed a consistently low level of osteoclast-specific bone resorption markers, while collagen-specific resorption and osteoblast-specific formation markers decreased at postpartum W+7 and from W+5, respectively. In the primiparous group, the plasma levels of all three markers decreased from postpartum W+3. These results suggest that the calcium demand during the transition from early to peak lactation in dairy cows is less affected by bone turnover.
authors: Cooperative Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, Morioka, Iwate 020-8550, Japan.
authors: Bhuminand
authors: B
authors: Devkota
authors: Masahiro
authors: M
authors: Takahashi
authors: Kouya
authors: K
authors: Sasaki
authors: Takeshi
authors: T
authors: Osawa
authors: Yoshiaki
authors: Y
authors: Izaike
authors: Norio
authors: N
authors: Yamagishi
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D015415:Biomarkers / Q000097:blood*; D001862:Bone Resorption / Q000378:metabolism*; D002118:Calcium / Q000097:blood; D002417:Cattle / Q000378:metabolism*; D003094:Collagen / Q000378:metabolism*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D007774:Lactation / Q000378:metabolism / Q000502:physiology*; D010012:Osteogenesis / Q000502:physiology*; D010298:Parity / Q000502:physiology*; D011247:Pregnancy
chemical_list: D015415:Biomarkers; D005230:Fatty Acids, Nonesterified; D003094:Collagen; D002118:Calcium