title: The aurora B kinase promotes inner and outer kinetochore interactions in budding yeast.
abstract: The kinetochore is the macromolecular protein complex that mediates chromosome segregation. The Dsn1 component is crucial for kinetochore assembly and is phosphorylated by the Aurora B kinase. We found that Aurora B phosphorylation of Dsn1 promotes the interaction between outer and inner kinetochore proteins in budding yeast.
authors: Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195, USA.
authors: Bungo
authors: B
authors: Akiyoshi
authors: Christian R
authors: CR
authors: Nelson
authors: Sue
authors: S
authors: Biggins
mesh_terms: D064107:Aurora Kinase B / Q000235:genetics* / Q000378:metabolism; D002868:Chromosomal Proteins, Non-Histone / Q000235:genetics*; D020090:Chromosome Segregation; D015966:Gene Expression Regulation, Fungal; D018386:Kinetochores / Q000378:metabolism / Q000648:ultrastructure; D008870:Microtubules / Q000378:metabolism / Q000648:ultrastructure; D008938:Mitosis / Q000235:genetics; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism; D010766:Phosphorylation; D060066:Protein Interaction Maps / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins / Q000235:genetics*
chemical_list: D002868:Chromosomal Proteins, Non-Histone; C470829:Dsn1 protein, S cerevisiae; D009687:Nuclear Proteins; D029701:Saccharomyces cerevisiae Proteins; D064107:Aurora Kinase B
keywords: Dsn1; Ipl1/Aurora B protein kinase; chromosome segregation; kinetochore
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