title: Impact of machines on plan quality: volumetric modulated arc therapy and intensity modulated radiation therapy.
abstract: OBJECTIVE
  To evaluate the impact of different machines on plan quality using both intensity modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) techniques.
  
  
  METHODS
  Eight patients with squamous cell carcinoma of the oropharynx were selected at random. Plans were computed for IMRT and VMAT Smart Arc, using Pinnacle TPS for an Elekta (IMRT-E, VMAT-E) and Varian linac (IMRT-V, VMAT-V). A three-dose level prescription was used to deliver 70, 63 and 58.1 Gy to regions of macroscopic, microscopic high- and low-risk disease, respectively. All doses were given in 35 fractions. Comparisons were performed on dose-volume histogram data, monitor units (MU), and delivery time.
  
  
  RESULTS
  VMAT-E plans resulted slightly MU efficient (-24 % p < 0.05) compared to VMAT-V while IMRT-V shortened delivery time (-19 % p < 0.05) compared to IMRT-E. All the delivery techniques resulted in equivalent target coverage in terms of D(98) % and D(2) %. For VMAT technique, a significant improvement of 7 % in homogeneity index (HI) for PTV58.1 was observed for Varian machine. A slight improvement in OARs sparing was observed with Elekta machine both for IMRT and VMAT techniques.
  
  
  CONCLUSIONS
  Similar plan quality was observed for Elekta and Varian linacs, significant differences were observed in delivery efficiency, as MU number and delivery times, in favor of Elekta and Varian, respectively.
authors: Department of Radiation Oncology, IRCCS CROB, Via Padre Pio n.1, 85028, Rionero in Vulture, PZ, Italy, clemente_stefania@libero.it.
authors: S
authors: S
authors: Clemente
authors: M
authors: M
authors: Cozzolino
authors: C
authors: C
authors: Oliviero
authors: A
authors: A
authors: Fiorentino
authors: C
authors: C
authors: Chiumento
authors: V
authors: V
authors: Fusco
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D004867:Equipment Design; D006801:Humans; D059351:Organ Sparing Treatments; D058958:Organs at Risk; D009959:Oropharyngeal Neoplasms / Q000532:radiotherapy; D010315:Particle Accelerators / Q000592:standards*; D011786:Quality Control; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation* / Q000592:standards*; D061089:Radiotherapy, Image-Guided / Q000295:instrumentation / Q000592:standards; D050397:Radiotherapy, Intensity-Modulated / Q000295:instrumentation* / Q000592:standards*
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