title: Capnocytophaga spp. involvement in bone infections: a review.
abstract: Capnocytophaga are commensal gliding bacteria that are isolated from human and animal oral flora and are responsible for infections both in immunocompromised and immunocompetent hosts. Accumulation of microbial plaque, loss of collagen attachment, and alveolar bone resorption around the tooth can lead to local Capnocytophaga spp. bone infections. These capnophilic bacteria, from oral sources or following domestic animal bites, are also causative agents of bacteraemia and systemic infections as well as osteomyelitis, septic arthritis, and infections on implants and devices. The present literature review describes the main aetiologies of bone infections due to Capnocytophaga spp., the cellular mechanisms involved, methods used for diagnosis, antimicrobial susceptibility, and effective treatments.
authors: Laboratoire de Bactériologie, Rennes University Hospital, rue Henri Le Guilloux, 35043 Rennes, France.
authors: Caroline
authors: C
authors: Piau
authors: Cédric
authors: C
authors: Arvieux
authors: Martine
authors: M
authors: Bonnaure-Mallet
authors: Anne
authors: A
authors: Jolivet-Gougeon
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002206:Capnocytophaga / Q000187:drug effects / Q000302:isolation & purification*; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D010019:Osteomyelitis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents