title: Controversial issues of optimal surgical timing and patient selection in the treatment planning of otosclerosis.
abstract: The aim of this study was to analyze the impact of clinical factors on the outcomes of otosclerosis surgery and support patients' access to evidence-based information in pre-operative counseling to optimize their choices. A total of 109 ears in 93 patients undergoing stapes surgery in a tertiary referral center were included. Variables with a potential impact on hearing outcomes were recorded, with an emphasis on factors that were readily available pre-operatively. Hearing success was defined as a post-operative air-bone gap ≤10 dB. Logistic regression analysis was used to determine the factors independently contributing to the prediction of hearing success. The mean follow-up period was 18.0 months. Univariate and multivariate analyses indicated that none of the pre-operative factors (piston type, age, sex, affected side, tinnitus, vertigo, and pre-operative hearing thresholds) affected hearing success significantly (all p > 0.05). In conclusion, self-crimping Nitinol piston provides comparable hearing outcomes with conventional manual-crimping prostheses. However, Nitinol piston offers a technical simplification of a surgical procedure and an easier surgical choice for patients. In addition, age is not a detriment to hearing gain and instead might result in better use of hearing aids in older adults, thus facilitating social hearing recovery. Finally, hearing success does not depend on the extent of pre-operative hearing loss. Hence, patients with poor cochlear function should not be considered poor candidates for surgery. The predictive model has established recommendations for otologists for better case selection, and factors that are readily available pre-operatively may inform patients more explicitly about expected post-operative audiometric results.
authors: Department of Otorhinolaryngology-Head and Neck Surgery, Taipei Veterans General Hospital, and National Yang-Ming University School of Medicine, 201, Section 2, Shih-Pai Road, Taipei, 112, Taiwan, asshiao@vghtpe.gov.tw.
authors: An-Suey
authors: AS
authors: Shiao
authors: Chin-Lung
authors: CL
authors: Kuo
authors: Hsiu-Lien
authors: HL
authors: Cheng
authors: Mao-Che
authors: MC
authors: Wang
authors: Chia-Huei
authors: CH
authors: Chu
mesh_terms: D000328:Adult; D001309:Auditory Threshold / Q000502:physiology; D001844:Bone Conduction / Q000502:physiology; D019317:Evidence-Based Medicine; D005260:Female; D006314:Hearing Loss, Conductive / Q000175:diagnosis / Q000601:surgery; D046089:Hearing Loss, Mixed Conductive-Sensorineural / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D009998:Ossicular Prosthesis; D010040:Otosclerosis / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D010347:Patient Care Planning; D010353:Patient Education as Topic; D018579:Patient Selection; D011183:Postoperative Complications / Q000175:diagnosis / Q000503:physiopathology; D011379:Prognosis; D011474:Prosthesis Design; D012189:Retrospective Studies; D013201:Stapes Surgery / Q000379:methods*
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