title: Structural revision of methyl tortuoate D, a bis-cembranoid from Hainan Sarcophyton tortuosum and its absolute stereochemistry.
abstract: Methyl tortuoate D (1), together with five other known related bis-cembranoids, was isolated from Hainan soft coral Sarcophyton tortuosum. The structure of methyl tortuoate D (1a), firstly isolated and reported by Li et al. from the title organism, was corrected as 1 by an extensive analysis of its one-dimensional and two-dimensional nuclear magnetic resonance data and by comparison with those reported in the literature. In addition, lobophytone K (1b), recently isolated from Hainan soft coral Lobophytum pauciflorum by Lin et al., was proved to be the same compound as 1 and 1a. The absolute configuration of 1 was determined by comparing its electronic circular dichroism curve with that of co-occurring ximaolide A (2).
authors: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Science, Shanghai 201203, China.
authors: Yu-Fen
authors: YF
authors: Li
authors: Ling-Li
authors: LL
authors: He
authors: Hai-Li
authors: HL
authors: Liu
authors: Lin-Fu
authors: LF
authors: Liang
authors: Hong-Bin
authors: HB
authors: Zhang
authors: Yue-Wei
authors: YW
authors: Guo
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification*; D004354:Drug Screening Assays, Antitumor; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D009792:Oceans and Seas
chemical_list: D004224:Diterpenes; C582536:methyl tortuoate D