title: Greater weight loss with increasing age in the weight loss maintenance trial.
abstract: OBJECTIVE
  To determine the effect of age on weight loss and weight loss maintenance in participants in the Weight Loss Maintenance trial (WLM).
  
  
  METHODS
  Secondary analysis of a randomized controlled trial of overweight/obese adults with CVD risk factors was conducted. Participants were 1685 adults with baseline BMI 25-45 kg m(2) with hypertension and/or dyslipidemia. Those who lost at least 4kg in an initial 6-month behavioral weight loss intervention (N = 1,032) were randomly assigned to a 30-month maintenance phase of self-directed control (SD), monthly personal counseling (PC), or unlimited access to an internet-based intervention (IT). Age groups were defined post-hoc and weight change was compared among age groups.
  
  
  RESULTS
  Participants ≥60 years old initially lost more weight than younger individuals, and sustained greater weight loss in IT and PC but not in SD (P value for trend 0.024, 0.002, and 0.36, respectively).
  
  
  CONCLUSIONS
  In WLM, adults age ≥60 years had greater initial weight loss and greater sustained weight loss over 3 years, compared to younger adults. Older adults had greater weight loss maintenance with either personal counseling or internet-based intervention. Future research should determine optimal implementation strategies and effects of weight loss on health outcomes in older adults.
authors: Division of Nephrology/Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA; Duke Hypertension Center and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina, USA.
authors: Laura P
authors: LP
authors: Svetkey
authors: Jeanne M
authors: JM
authors: Clark
authors: Kristine
authors: K
authors: Funk
authors: Leonor
authors: L
authors: Corsino
authors: Bryan C
authors: BC
authors: Batch
authors: Jack F
authors: JF
authors: Hollis
authors: Lawrence J
authors: LJ
authors: Appel
authors: Phillip J
authors: PJ
authors: Brantley
authors: Catherine M
authors: CM
authors: Loria
authors: Catherine M
authors: CM
authors: Champagne
authors: William M
authors: WM
authors: Vollmer
authors: Victor J
authors: VJ
authors: Stevens
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D050171:Dyslipidemias / Q000150:complications; D005247:Feeding Behavior; D006801:Humans; D006973:Hypertension / Q000150:complications; D008875:Middle Aged; D009043:Motor Activity; D009765:Obesity / Q000628:therapy; D050177:Overweight / Q000628:therapy; D012307:Risk Factors; D011795:Surveys and Questionnaires; D015431:Weight Loss; D061217:Weight Reduction Programs
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