title: Feline anaplastic oligodendroglioma: long-term remission through radiation therapy and chemotherapy.
abstract: A 10-year-old spayed female Abyssinian cat was presented with cluster limbic focal seizures with secondary generalisation. From magnetic resonance imaging (MRI) findings, the cat was diagnosed clinically as having a glioma in the left piriform lobe, and hypofractionated radiation therapy (RT) was performed using a linear accelerator. Although the tumour size had reduced significantly at 4 months after RT, recurrence was observed at 11 months after RT. Additional RT was performed and was effective; however, recurrence was observed at 11 months after the additional RT. Chemotherapy was started using nimustine (ACNU; 30 mg/m(2), every 6 weeks). Tumour regression was confirmed by follow-up MRIs from 2 to 5 months after starting chemotherapy. Four years and 2 months after the first presentation the cat died as a result of tumour lysis syndrome following treatment of a high-grade lymphoma. Histopathological diagnosis of the brain tumour confirmed anaplastic oligodendroglioma.
authors: 1Department of Veterinary Science, Nippon Veterinary and Life Science University, Tokyo, Japan.
authors: Masahiro
authors: M
authors: Tamura
authors: Daisuke
authors: D
authors: Hasegawa
authors: Kazuyuki
authors: K
authors: Uchida
authors: Takayuki
authors: T
authors: Kuwabara
authors: Shunta
authors: S
authors: Mizoguchi
authors: Naoko
authors: N
authors: Ochi
authors: Michio
authors: M
authors: Fujita
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002371:Cat Diseases / Q000473:pathology / Q000628:therapy*; D002415:Cats; D017809:Fatal Outcome; D005260:Female; D009837:Oligodendroglioma / Q000188:drug therapy / Q000532:radiotherapy / Q000662:veterinary*; D015275:Tumor Lysis Syndrome / Q000473:pathology / Q000662:veterinary
chemical_list: D000970:Antineoplastic Agents
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