title: Comparative study on the photostability of arbutin and deoxy arbutin: sensitivity to ultraviolet radiation and enhanced photostability by the water-soluble sunscreen, benzophenone-4.
abstract: Arbutin and deoxy arbutin may release hydroquinone under some conditions. We therefore investigated the photostability of arbutin and deoxy arbutin in an aqueous solution. The results revealed arbutin and deoxy arbutin to be photolabile in an aqueous solution. Deoxy arbutin was less stable than arbutin when exposed to UV radiation. The hydroquinone concentration was also increased during the radiation period in both solutions. Benzophenone-4 could clearly improve the photostability of arbutin during the period of UV radiation, but only slightly enhance the photostability of deoxy arbutin.
authors: Department of Cosmetic Science, Providence University, Taiwan Boulevard, Shalu, Taichung, Taiwan, ROC.
authors: Chao-Hsun
authors: CH
authors: Yang
authors: Nai-Fang
authors: NF
authors: Chang
authors: Yi-Shyan
authors: YS
authors: Chen
authors: Shu-Mei
authors: SM
authors: Lee
authors: Pei-Jin
authors: PJ
authors: Lin
authors: Chih-Chien
authors: CC
authors: Lin
mesh_terms: D001104:Arbutin / Q000031:analogs & derivatives* / Q000737:chemistry; D001577:Benzophenones / Q000737:chemistry*; D004355:Drug Stability; D055668:Photochemical Processes; D012995:Solubility; D013473:Sunscreening Agents / Q000737:chemistry*; D014466:Ultraviolet Rays; D014867:Water / Q000737:chemistry*
chemical_list: D001577:Benzophenones; D013473:Sunscreening Agents; D014867:Water; C009361:sulisobenzone; D001104:Arbutin; C504954:deoxyarbutin