title: Global comparative healthcare effectiveness research: evaluating sustainable programmes in low & middle resource settings.
abstract: The need to focus healthcare expenditures on innovative and sustainable health systems that efficiently use existing effective therapies are the major drivers stimulating Comparative Effectiveness Research (CER) across the globe. Lack of adequate access and high cost of essential medicines and technologies in many countries increases morbidity and mortality and cost of care that forces people and families into poverty due to disability and out-of-pocket expenses. This review illustrates the potential of value-added global health care comparative effectiveness research in shaping health systems and health care delivery paradigms in the "global south". Enabling the development of effective CER systems globally paves the way for tangible local and regional definitions of equity in health care because CER fosters the sharing of critical assets, resources, skills, and capabilities and the development of collaborative of multi-sectorial frameworks to improve health outcomes and metrics globally.
authors: Clinical, Social and Administrative Sciences, College of Pharmacy, Department of Health Management and Policy, The University of Michigan at Ann Arbor, 428 Church Street, Ann Arbor, MI 48109-1065, USA.
authors: Rajesh
authors: R
authors: Balkrishnan
authors: Jongwha
authors: J
authors: Chang
authors: Isha
authors: I
authors: Patel
authors: Fang
authors: F
authors: Yang
authors: Sofia D
authors: SD
authors: Merajver
mesh_terms: D057186:Comparative Effectiveness Research / Q000191:economics*; D003362:Cost-Benefit Analysis; D003695:Delivery of Health Care / Q000191:economics*; D006295:Health Resources / Q000191:economics; D006301:Health Services Needs and Demand / Q000191:economics*; D006801:Humans; D011203:Poverty / Q000191:economics; D015397:Program Evaluation
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