title: New insights into the population structure of Anopheles gambiae s.s. in the Gulf of Guinea Islands revealed by Herves transposable elements.
abstract: Transposable elements (TEs) are mobile portions of DNA that are able to replicate and spread in the genome of many organisms. TEs can be used as a means to insert transgenes in insects, being stably inherited throughout generations. Anopheles gambiae is the main vector of human malaria in Sub-Saharan Africa. Given the extraordinary burden this disease imposes, the mosquito became a choice target for genetic control approaches with the purpose of reducing malaria transmission. In this study, we investigated the abundance and distribution of Herves TE in An. gambiae s.s. from Cameroon and four islands in the Gulf of Guinea, in order to determine their genetic structure. We have detected a population subdivision between Equatorial Guinea islands and the islands of São Tomé, Príncipe and mainland. This partitioning associates more with political rather than geographic boundaries, possibly reflecting different mainland source populations colonizing the islands.
authors: Centro de Malária e outras Doenças Tropicais/UEI Parasitologia Médica, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisboa, Portugal.
authors: Patrícia
authors: P
authors: Salgueiro
authors: Marta
authors: M
authors: Moreno
authors: Frédéric
authors: F
authors: Simard
authors: David
authors: D
authors: O'Brochta
authors: João
authors: J
authors: Pinto
mesh_terms: D000818:Animals; D000852:Anopheles / Q000235:genetics*; D004251:DNA Transposable Elements / Q000235:genetics*; D014644:Genetic Variation; D005838:Genotype; D005843:Geography; D016701:Guinea; D006801:Humans; D062312:Islands; D011157:Population Dynamics; D025341:Principal Component Analysis
chemical_list: D004251:DNA Transposable Elements
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