title: Glomerular filtration rate is associated with burden of coronary atherosclerosis in patients with acute coronary syndrome.
abstract: We aimed to elucidate the relationship between mild to moderate renal impairements and burden of atherosclerosis in patients with acute coronary syndrome (ACS). A total of 380 patients with ACS were included in the study. Gensini and SYNTAX scores were also calculated. Kidney function was classified based on estimated glomerular filtration rate (eGFR) into stage 1: eGFR >90, stage 2: 60 to 89, and stage 3: 30 to 60 mL/min per 1.73 m(2). Gensini and SYNTAX scores were higher in stages 2 and 3 than in stage 1. Also, the number of diseased vessels, number of critical lesions (>50 and 70%), left main disease, and number of total occlusion vessels were higher in stages 2 and 3 than in stage 1. Multivariate linear regression analysis demonstrated that a decreased eGFR was an independent risk factor for SYNTAX and Gensini scores together with age and male gender.
authors: 1Ankara Research and Education Hospital, Ankara, Turkey.
authors: Mustafa
authors: M
authors: Duran
authors: Onur Kadir
authors: OK
authors: Uysal
authors: Ozgur
authors: O
authors: Gunebakmaz
authors: Oguzhan
authors: O
authors: Baran
authors: Murat
authors: M
authors: Turfan
authors: Ender
authors: E
authors: Ornek
authors: Mustafa
authors: M
authors: Cetin
authors: Sani Namik
authors: SN
authors: Murat
authors: Mikail
authors: M
authors: Yarlioglues
authors: Muhammed
authors: M
authors: Karadeniz
authors: Alpaslan
authors: A
authors: Kurtul
authors: Mehmet Gungor
authors: MG
authors: Kaya
mesh_terms: D054058:Acute Coronary Syndrome / Q000150:complications* / Q000175:diagnosis; D000328:Adult; D000367:Age Factors; D000368:Aged; D016009:Chi-Square Distribution; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000150:complications* / Q000175:diagnosis; D054059:Coronary Occlusion / Q000150:complications / Q000175:diagnosis; D023921:Coronary Stenosis / Q000150:complications / Q000175:diagnosis; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D007674:Kidney Diseases / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D012737:Sex Factors
keywords: Gensini score; SYNTAX score; acute coronary syndrome; glomerular filtration rate