title: Cognitive approaches to early Alzheimer's disease diagnosis.
abstract: In this article, cognitive measures in the screening of individuals at risk for Alzheimer disease (AD) are reviewed. Use of cognitive tasks in identifying clinical cases of AD is considered, as well as methods for detecting those in the prodromal stages of the disease, including cognitive screening instruments. Traditional assessments, such as the mini-mental state examination, as well as contemporary computerized screening instruments, are examined. Areas of cognition for investigation in the detection of prodromal AD are recommended. The prospects for general cognitive screening are reviewed, and more engaging technologies to tests individuals at risk for developing AD are recommended.
authors: Department of Medicine, Imperial College, London & Metis Cognition Ltd, Park House, Kilmington Common, Wiltshire, UK. john@metiscog.com
authors: John
authors: J
authors: Harrison
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000523:psychology; D058070:Asymptomatic Diseases / Q000523:psychology*; D003661:Decision Support Techniques; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D006801:Humans; D008403:Mass Screening; D008609:Mental Status Schedule / Q000706:statistics & numerical data*; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D011594:Psychometrics / Q000706:statistics & numerical data; D015203:Reproducibility of Results