title: Post-steroid management of chronic vulvar itching with a topical formula containing natural anti-itching and anti-inflammatory actives.
abstract: OBJECTIVE
  To determine whether use of a topical, nonsteroidal, anti-inflammatory, and anti-itching formula was able to preserve the absence of symptoms, mainly itching and burning, induced by an earlier and relatively short treatment with topical steroids in women diagnosed with vulvar dermatitis or lichen simplex.
  
  
  METHODS
  Ninety-six subjects (36 with contact dermatitis, 29 with allergic dermatitis, 31 with lichen simplex) were enrolled in the study. All participants were first treated with topical mometasone furoate (MF) 0.1%. When the symptoms disappeared, they were treated either with Zantogin(®), a multicomponent topical formula containing anti-inflammatory and anti-itching natural actives, or a control cream for 60 days.
  
  
  RESULTS
  The study demonstrated that, in about 85% of the participants treated with Zantogin(®), symptoms disappeared completely, and only 15% had to resort to MF as needed, with an average use of about three applications per subject (in total). In the placebo group, approximately 90% of participants had to resort to MF as needed, with an average use per person of more than 16 applications in 60 days.
  
  
  CONCLUSIONS
  Our study demonstrates that, following use of a topical steroid, symptoms such as burning and itching can be validly controlled with subsequent and longer therapy with a herbal topical formula, Zantogin(®), which is able to properly counteract itching and inflammation, prevent symptom relapse, and avoid the typical side effects associated with prolonged use of topical steroids.
authors: Velleja Research, Milan, Italy.
authors: Francesco
authors: F
authors: Di Pierro
authors: Eleonora
authors: E
authors: Di Maio
authors: Gaetana
authors: G
authors: Di Paola
authors: Raffaele
authors: R
authors: Felice
authors: Filippo
authors: F
authors: Murina
keywords: Zantogin®; lichen simplex chronicus; vulvar dermatitis; vulvar itching; zanthalene
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