title: Positivity of serum "classical" onconeural antibodies in a series of 2063 consecutive patients with suspicion of paraneoplastic neurological syndrome.
abstract: This study determined the prevalence of classical onconeural Ab in a series of 2063 consecutive patients that were investigated because of suspicion of PNS as well as evaluated individual onconeural Ab in relationship to the clinical spectrum of associated neurological syndromes and tumor types detected in 70 patients finally diagnosed with PNS. We conclude that detectability of onconeural Ab is low among patients suspected with PNS. Specification of Ab is helpful in defining a neurological syndrome as paraneoplastic as well as in searching of underlying tumor. The success in tumor screening depends on the type of onconeural Ab.
authors: Second Department of Neurology, Institute of Psychiatry and Neurology, Sobieskiego 9, 02-957 Warsaw, Poland. gragrom@ipin.edu.pl
authors: Grażyna
authors: G
authors: Gromadzka
authors: Anna G
authors: AG
authors: Karlińska
authors: Zofia
authors: Z
authors: Łysiak
authors: Beata
authors: B
authors: Błażejewska-Hyżorek
authors: Tomasz
authors: T
authors: Litwin
authors: Anna
authors: A
authors: Członkowska
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000912:Antibodies, Neoplasm / Q000097:blood; D001323:Autoantibodies / Q000097:blood*; D001943:Breast Neoplasms / Q000453:epidemiology / Q000276:immunology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology / Q000276:immunology; D008223:Lymphoma / Q000453:epidemiology / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology* / Q000276:immunology*; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000276:immunology; D020361:Paraneoplastic Syndromes, Nervous System / Q000453:epidemiology* / Q000276:immunology*; D016036:Seroepidemiologic Studies; D014594:Uterine Neoplasms / Q000453:epidemiology / Q000276:immunology; D055815:Young Adult
chemical_list: D000912:Antibodies, Neoplasm; D001323:Autoantibodies