title: Genetic relatedness of dengue viruses in Key West, Florida, USA, 2009-2010.
abstract: Sequencing of dengue virus type 1 (DENV-1) strains isolated in Key West/Monroe County, Florida, indicate endemic transmission for >2 years of a distinct and predominant sublineage of the American-African genotype. DENV-1 strains isolated elsewhere in Florida grouped within a separate Central American lineage. Findings indicate endemic transmission of DENV into the continental United States.
authors: Dengue Branch, Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico. ckq2@cdc.gov
authors: Jorge L
authors: JL
authors: Muñoz-Jordán
authors: Gilberto A
authors: GA
authors: Santiago
authors: Harold
authors: H
authors: Margolis
authors: Lillian
authors: L
authors: Stark
mesh_terms: D000330:Aedes / Q000821:virology; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D003715:Dengue / Q000097:blood / Q000453:epidemiology* / Q000821:virology; D003716:Dengue Virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D019353:Endemic Diseases; D005431:Florida / Q000453:epidemiology; D005838:Genotype; D006801:Humans; D015994:Incidence; D007303:Insect Vectors / Q000821:virology; D010802:Phylogeny; D012189:Retrospective Studies; D017422:Sequence Analysis, DNA; D014764:Viral Proteins / Q000145:classification / Q000235:genetics*
chemical_list: D000914:Antibodies, Viral; D014764:Viral Proteins
keywords: DENV-1; Florida; Key West; dengue virus; phylogeny; vector-borne infections; viruses
references: J Clin Microbiol. 1992 Mar;30(3):545-51
references: 1372617
references: J Travel Med. 2010 Jan-Feb;17(1):8-14
references: 20074096
references: Infect Genet Evol. 2003 May;3(1):19-28
references: 12797969
references: N Engl J Med. 2006 Jan 12;354(2):119-30
references: 16407507
references: Emerg Infect Dis. 2012 Jan;18(1):135-7
references: 22257471
references: J Clin Microbiol. 2005 Oct;43(10):4977-83
references: 16207951
references: Emerg Infect Dis. 2011 Nov;17(11):2074-5
references: 22099104
references: Am J Trop Med Hyg. 2012 Sep;87(3):548-53
references: 22826483
references: J Clin Microbiol. 2000 May;38(5):1823-6
references: 10790107
references: Bull World Health Organ. 1985;63(2):279-86
references: 2861916
references: Adv Virus Res. 2003;59:315-41
references: 14696333
references: MMWR Morb Mortal Wkly Rep. 2010 May 21;59(19):577-81
references: 20489680
references: Am J Trop Med Hyg. 2008 Mar;78(3):364-9
references: 18337327