title: The relationship between psychosocial functioning and resilience and negative symptoms in individuals at ultra-high risk for psychosis.
abstract: OBJECTIVE
  Decline in psychosocial functioning seems to be a core feature in schizophrenia across various phases of the disorder. Little is known about the relationship between psychosocial functioning and protective factors or psychopathologies in individuals in the prodrome phase of psychosis. We aimed to investigate whether psychosocial functioning is impaired in individuals in the putative prodromal phase of schizophrenia, and, if so, to identify factors associated with compromised psychosocial functioning.
  
  
  METHODS
  Sixty participants at ultra-high risk (UHR) for psychosis and 47 healthy controls were recruited. All subjects were assessed in terms of psychosocial functioning using the Quality of Life Scale. A clinical assessment of psychopathology and protective factors, including resilience and coping style, was also conducted.
  
  
  RESULTS
  Psychosocial functioning in UHR participants was found to be compromised; this dysfunction was associated with negative symptoms, adaptive coping, and resilience. In addition, baseline resilience was lower among those in the UHR group who converted to frank psychosis than among those who did not.
  
  
  CONCLUSIONS
  These findings imply that treatment strategies for individuals at UHR for psychosis should be comprehensive, promoting resilience as well as targeting the reduction of positive and negative symptoms to foster social reintegration and recovery.
authors: Department of Psychiatry, Yonsei University College of Medicine, Severance Hospital, Seoul, South Korea.
authors: Kyung Ran
authors: KR
authors: Kim
authors: Yun Young
authors: YY
authors: Song
authors: Jin Young
authors: JY
authors: Park
authors: Eun Hye
authors: EH
authors: Lee
authors: Mikyung
authors: M
authors: Lee
authors: Su Young
authors: SY
authors: Lee
authors: Jee In
authors: JI
authors: Kang
authors: Eun
authors: E
authors: Lee
authors: Sang Woo
authors: SW
authors: Yoo
authors: Suk Kyoon
authors: SK
authors: An
authors: Jun Soo
authors: JS
authors: Kwon
mesh_terms: D000223:Adaptation, Psychological; D005260:Female; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000175:diagnosis / Q000523:psychology*; D011788:Quality of Life; D055500:Resilience, Psychological; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis; D012565:Schizophrenic Psychology; D012917:Social Adjustment; D012944:Social Support
keywords: Psychosocial function; negative symptoms; resilience; ultra-high risk for psychosis