title: Nocturia and sleep quality after transurethral resection of the prostate.
abstract: OBJECTIVE
  To evaluate the clinical efficacy of transurethral resection of the prostate on nocturia and sleep disorders in patients with lower urinary tract symptoms suggestive of benign prostatic obstruction.
  
  
  METHODS
  A prospective multicenter study including lower urinary tract symptoms suggestive of benign prostatic obstruction patients with nocturia (twice or more) undergoing transurethral resection of the prostate was carried out. All patients were assessed using the International Prostate Symptom Score and the Pittsburgh Sleep Quality Index at baseline, and 6 months after transurethral resection of the prostate.
  
  
  RESULTS
  Overall, 49 patients were included in the study. A total of 20 of them (41%) had a sleep disorder defined as a score of 5.5 or more on the Pittsburgh Sleep Quality Index global score. The nocturia score significantly correlated with component 4 of the Pittsburgh Sleep Quality Index (habitual sleep efficiency). Nocturia significantly decreased after transurethral resection of the prostate from 3.0 ± 1.2 to 1.9 ± 0.8, whereas the global Pittsburgh Sleep Quality Index score did not. In 20 patients with a sleep disorder before transurethral resection of the prostate, subjective sleep quality (component 1) and habitual sleep efficiency (component 4) significantly decreased after transurethral resection of the prostate, but this was not the case for the global Pittsburgh Sleep Quality Index score. In 16 patients with a persistent sleep disorder after transurethral resection of the prostate, International Prostate Symptom Score, voiding and storage symptoms score were higher than those of patients without a sleep disorder, although the nocturia score improved equivalently in both groups.
  
  
  CONCLUSIONS
  Transurethral resection of the prostate diminishes nocturnal urinary frequency and partly improves sleep quality in patients with nocturia and lower urinary tract symptoms suggestive of benign prostatic obstruction. A persistent sleep disorder after transurethral resection of the prostate is associated with persistent voiding and storage symptoms.
authors: Department of Renal and Urologic Surgery, Asahikawa Medical University, Asahikawa, Japan.
authors: Naoki
authors: N
authors: Wada
authors: Atsushi
authors: A
authors: Numata
authors: Kyokushin
authors: K
authors: Hou
authors: Masaki
authors: M
authors: Watanabe
authors: Masafumi
authors: M
authors: Kita
authors: Seiji
authors: S
authors: Matsumoto
authors: Hiroaki
authors: H
authors: Osanai
authors: Makoto
authors: M
authors: Fujisawa
authors: Hidehiro
authors: H
authors: Kakizaki
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D053158:Nocturia / Q000209:etiology*; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000150:complications* / Q000601:surgery*; D012893:Sleep Wake Disorders / Q000209:etiology*; D020728:Transurethral Resection of Prostate
keywords: nocturia; sleep disturbance; transurethral resection of the prostate