title: Vasculitis resulting from a superficial femoral artery angioplasty with a paclitaxel-eluting balloon.
abstract: Drug-eluting balloons (DEBs) coated with the antiproliferative agent paclitaxel may improve primary patency by reducing recurrent luminal stenosis. A proportion of the active drug and excipient coating are known to embolize distally, but until now, there have been no reports of adverse events resulting from their use. We report an unusual case of a painful nodular, biopsy specimen-proven vasculitic rash that afflicted the ipsilateral lower limb of a patient after superficial femoral artery treatment with a DEB. This adverse event may have implications for the use of DEB in this and other vascular territories.
authors: Department of Surgery, Prince of Wales Hospital, Sydney, New South Wales, Australia.
authors: Shannon D
authors: SD
authors: Thomas
authors: Sky Blue Dermatology, Sydney, New South Wales, Australia; Department of Dermatology, St. Vincent's Hospital, Sydney, New South Wales, Australia.
authors: Robert R A
authors: RR
authors: McDonald
authors: Department of Surgery, Prince of Wales Hospital, Sydney, New South Wales, Australia; Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia; The Vascular Institute, Prince of Wales Hospital, Sydney, New South Wales, Australia. Electronic address: r.varcoe@unsw.edu.au.
authors: Ramon L
authors: RL
authors: Varcoe
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon / Q000009:adverse effects* / Q000295:instrumentation*; D001706:Biopsy; D002317:Cardiovascular Agents / Q000008:administration & dosage*; D020099:Coated Materials, Biocompatible; D005260:Female; D005263:Femoral Artery / Q000503:physiopathology; D006801:Humans; D007383:Intermittent Claudication / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D017239:Paclitaxel / Q000008:administration & dosage*; D016896:Treatment Outcome; D062666:Vascular Access Devices; D014654:Vascular Patency; D014657:Vasculitis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
chemical_list: D002317:Cardiovascular Agents; D020099:Coated Materials, Biocompatible; D017239:Paclitaxel