title: Intra-aortic balloon shape change: effects on volume displacement during inflation and deflation.
abstract: It has been observed that operating the intra-aortic balloon at an angle to the horizontal resulted in a reduction of the volume displaced toward the coronary arteries and compromised afterload reduction. Therefore, the aim of this work is to examine whether changing the current balloon shape, which has not been altered for 40 years, could compensate for the negative hemodynamic effects due to angulation. We tested two tapered balloons, increasing diameter (TID) and decreasing diameter (TDD), and compared the results with those obtained from a standard cylindrical balloon. The balloons were tested in vitro at 60 beats/min and a static pressure of 90 mm Hg. The balloons were operated at four angles (0°, 20°, 30°, 45°), and the pressure at three locations along the balloon (base, middle, and tip) was also measured. Flow rate upstream of the tip of the balloon was also measured to indicate the flow displaced toward the coronary circulation. The relative volume displaced toward (VUTVi) and suctioned away from (VUTVd) the simulated ascending aorta, during inflation and deflation, respectively, is reduced when a standard cylindrical balloon is operated at an angle to the horizontal. The TDD provided the greatest VUTVi and also produced the largest pulse pressure during deflation. Although the TID provided less VUTVi and VUTVd at smaller angles, it was not markedly affected by the change of angle. According to these results, different balloon shapes analyzed, with comparable volume to that of a cylindrical balloon, produced greater inflation and deflation benefits, at the horizontal and at a range of angles to the horizontal. Further investigations are required to optimize the shape of the tapered balloons to fit into the available physiological space.
authors: Brunel Institute for Bioengineering, Brunel University, Uxbridge, Middlesex, UK. ashraf.khir@brunel.ac.uk
authors: Ashraf William
authors: AW
authors: Khir
authors: Gianpaolo
authors: G
authors: Bruti
mesh_terms: D001011:Aorta / Q000503:physiopathology*; D001783:Blood Flow Velocity; D003326:Coronary Circulation; D004867:Equipment Design; D006333:Heart Failure / Q000503:physiopathology / Q000628:therapy*; D006439:Hemodynamics; D006801:Humans; D007423:Intra-Aortic Balloon Pumping / Q000295:instrumentation*; D008422:Materials Testing; D008953:Models, Anatomic; D008955:Models, Cardiovascular; D012039:Regional Blood Flow; D013997:Time Factors
keywords: Balloon shape; Inflation and deflation; Intra-aortic balloon pump; Volume displacement