title: Outcomes of primary total joint arthroplasty after lung transplantation.
abstract: Lung transplantation is increasingly common with improving survival rates. Post-transplant patients can be expected to seek total hip (THA) and knee arthroplasty (TKA) to improve their quality of life. Outcomes of 20 primary total joint arthroplasties (15 THA, 5 TKA) in 14 patients with lung transplantation were reviewed. Clinical follow-up time averaged 27.5 and 42.8 months for THA and TKA respectively. Arthroplasty indications included osteonecrosis, osteoarthritis, and fracture. All patients subjectively reported good or excellent outcomes with a final average Harris Hip Score of 88.7, Knee Society objective and functional score of 92.0. There were 4 minor and 1 major acute perioperative complications. 1 late TKA infection was successfully treated with two-stage revision. The mortality rate was 28.5% (4/14 patients) at an average 20.6 months following but unrelated to arthroplasty. Overall, total joint arthroplasty can be safely performed and provide good functional outcomes in lung transplant recipients.
authors: Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina.
authors: Cameron K
authors: CK
authors: Ledford
authors: Tyler Steven
authors: TS
authors: Watters
authors: Samuel S
authors: SS
authors: Wellman
authors: David E
authors: DE
authors: Attarian
authors: Michael P
authors: MP
authors: Bolognesi
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D019645:Arthroplasty, Replacement, Knee; D005260:Female; D050723:Fractures, Bone / Q000601:surgery; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007592:Joint Diseases / Q000150:complications / Q000209:etiology / Q000601:surgery*; D008171:Lung Diseases / Q000150:complications / Q000188:drug therapy / Q000601:surgery*; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents
keywords: hip arthroplasty; immunosuppression; knee arthroplasty; lung transplantation