title: Hydroa vacciniforme-like lymphoma of an adult: a case report with review of the literature.
abstract: Hydroa vacciniforme-like lymphoma (HVL) is a rare type of Epstein-Barr virus (EBV)-positive lymphoma of cytotoxic T-cell or natural killer cell origin that mainly affect children, characterized by a vesicopapular skin eruption that clinically resemble hydroa vacciniforme (HV). In current study, we report an adult patient with the tumor. The patient presented similar morphologic, immunophenotypic and genotypic changes of the disease with that occurred in children, whereas clinically, he showed a prolonged clinical course without hepatosplenomegaly or generalized lymphadenopathy. Whether there are some differences in biologic behavior between children and adults still remains unknown and it is necessary to collect more data to observe and to investigate in the future.
  The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/7644172219178472.
authors: Department of Dermatovenerology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
authors: Mi
authors: M
authors: Wang
authors: Sheng
authors: S
authors: Wang
authors: Qun-Pei
authors: QP
authors: Yang
authors: Yan-Mei
authors: YM
authors: Liu
authors: Li-Min
authors: LM
authors: Gao
authors: Hong
authors: H
authors: Sun
authors: Wei-Ping
authors: WP
authors: Liu
mesh_terms: D020031:Epstein-Barr Virus Infections / Q000150:complications / Q000175:diagnosis; D006801:Humans; D006837:Hydroa Vacciniforme / Q000175:diagnosis / Q000473:pathology* / Q000821:virology; D017403:In Situ Hybridization / Q000379:methods; D007694:Killer Cells, Natural / Q000473:pathology / Q000821:virology*; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis / Q000473:pathology* / Q000821:virology; D008297:Male; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000821:virology; D055815:Young Adult
references: Br J Dermatol. 1996 Apr;134(4):791-6
references: 8733395
references: Appl Immunohistochem Mol Morphol. 2002 Mar;10(1):7-14
references: 11893040
references: Hum Pathol. 2009 Jun;40(6):807-16
references: 19200574
references: Clin Exp Dermatol. 2001 May;26(3):242-7
references: 11422165
references: Ann Oncol. 2009 Sep;20(9):1472-1482
references: 19515747
references: Pediatr Dermatol. 2010 Sep-Oct;27(5):463-9
references: 20497358
references: J Am Acad Dermatol. 1998 Apr;38(4):574-9
references: 9580256