title: [Visual cortex and its participation in retinal function regulation].
abstract: The study of visual cortex local changes caused by strychnine and potassium chloride revealed significant changes (relief or depression) not of evoked potentials in the cortex only, but of unidirectional changes of the total electroretinogram (ERG) amplitude and its components as well (early receptor and oscillator retinal potentials). Cortex excitability decrease or increase resulted in inhibition or facilitation of early receptor potential development respectively due to weakening or strengthening of the inhibitory neurotransmitter GABA effect in photoreceptor synapses. Changes of ERG components and retinal oscillator potential corresponded to the changes of visual evoked potentials that reflected upon cortex inhibition or facilitation. This fact apparently indicates the changes of inhibitory neurotransmitter glutamate activity.
authors: N M
authors: NM
authors: Rzaeva
authors: A I
authors: AI
authors: Dmitrienko
mesh_terms: D000818:Animals; D004596:Electroretinography / Q000379:methods; D005074:Evoked Potentials, Visual / Q000502:physiology; D018684:Glycine Agents; D023421:Models, Animal; D009434:Neural Pathways / Q000187:drug effects / Q000378:metabolism / Q000503:physiopathology; D010775:Photic Stimulation / Q000379:methods; D010786:Photoreceptor Cells / Q000502:physiology; D011817:Rabbits; D012160:Retina / Q000378:metabolism / Q000503:physiopathology; D013331:Strychnine / Q000494:pharmacology*; D013569:Synapses / Q000378:metabolism*; D014793:Visual Cortex / Q000187:drug effects / Q000378:metabolism / Q000503:physiopathology; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
chemical_list: D018684:Glycine Agents; D005680:gamma-Aminobutyric Acid; D013331:Strychnine