title: Evaluation of the efficacy of a bioactive synthetic graft material in the treatment of intrabony periodontal defects.
abstract: BACKGROUND
  Bioactive ceramic fillers are synthetic materials which have shown the potential to enhance bone formation. The purpose of this study was to evaluate the efficacy of a bioactive synthetic graft material in the treatment of intrabony periodontal defects.
  
  
  METHODS
  Fourteen intrabony defects in twelve systemically healthy subjects having moderate to severe chronic periodontitis were evaluated after bone grafting with bioactive ceramic filler for a period of 6 months. Clinical and radiographic evaluations were made at baseline, at 3 and 6 months following surgery.
  
  
  RESULTS
  Mean radiographic defect fill of 64.76% (2.49±0.5 mm) was observed in 6 months, which was statistically significant. A statistically significant relative attachment level gain of 2.71±1.13 mm and probing pocket depth reduction of 4.21±1.18 mm was recorded at the end of the study. A significant decrease in mobility and gingival index was observed.
  
  
  CONCLUSIONS
  Bioactive glass is an efficacious treatment option for the reconstruction of intrabony periodontal defects as it led to statistically significant improvements in the clinical and radiographic parameters.
authors: Department of Periodontology and Oral Implantology, National Dental College and Hospital, Derabassi, Punjab, India.
authors: Vishakha
authors: V
authors: Grover
authors: Anoop
authors: A
authors: Kapoor
authors: Ranjan
authors: R
authors: Malhotra
authors: Ranjit Singh
authors: RS
authors: Uppal
keywords: Bioactive glass; intrabony defects; periodontitis; regeneration
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