title: Trial watch: Sepsis study failure highlights need for trial design rethink.
authors: Man Tsuey
authors: MT
authors: Tse
mesh_terms: D002986:Clinical Trials as Topic; D017326:Clinical Trials, Phase III as Topic; D004187:Disaccharides / Q000627:therapeutic use*; D055808:Drug Discovery / Q000639:trends; D006801:Humans; D008070:Lipopolysaccharides / Q000378:metabolism; D012107:Research Design; D018805:Sepsis / Q000188:drug therapy*; D012772:Shock, Septic / Q000188:drug therapy; D013403:Sugar Phosphates / Q000627:therapeutic use*; D051197:Toll-Like Receptor 4 / Q000037:antagonists & inhibitors
chemical_list: D004187:Disaccharides; D008070:Lipopolysaccharides; D013403:Sugar Phosphates; D051197:Toll-Like Receptor 4; C512420:eritoran
references: JAMA. 2013 Mar 20;309(11):1154-62
references: 23512062