title: Specimen-specific tibial kinematics model for in vitro gait simulations.
abstract: Until now, the methods used to set up in vitro gait simulations were not specimen specific, inflicting several problems when dealing with specimens of considerably different dimensions and requiring arbitrary parameter tuning of the control variables. We constructed a model that accounts for the geometric dimensions of the specimen and is able to predict the tibial kinematics during the stance phase. The model predicts tibial kinematics of in vivo subjects with very good accuracy. Furthermore, if used in in vitro gait simulation studies, it is able to recreate physiological vertical ground reaction forces. By using this methodology, in vitro studies can be performed by taking the specimen variability into account, avoiding pitfalls with specimens of different dimensions.
authors: Department of Mechanical Engineering, Faculty of Engineering KU Leuven, Belgium. tassos.natsakis@mech.kuleuven.be
authors: Tassos
authors: T
authors: Natsakis
authors: Koen
authors: K
authors: Peeters
authors: Fien
authors: F
authors: Burg
authors: Greta
authors: G
authors: Dereymaeker
authors: Jos
authors: J
authors: Vander Sloten
authors: Ilse
authors: I
authors: Jonkers
mesh_terms: D000328:Adult; D000465:Algorithms; D001696:Biomechanical Phenomena; D003198:Computer Simulation; D004867:Equipment Design; D005684:Gait / Q000502:physiology*; D006801:Humans; D008953:Models, Anatomic; D008954:Models, Biological; D015233:Models, Statistical; D013314:Stress, Mechanical; D013977:Tibia / Q000473:pathology*; D016138:Walking / Q000502:physiology; D016474:Weight-Bearing / Q000502:physiology
keywords: In vitro gait simulations; gait analysis; specimen specificity; tibial kinematics