title: [Increase of newborns with anorectal malformation in 2011. Is it just by chance?].
abstract: OBJECTIVE
  In 2011 we have diagnosed 9 anorectal malformations (MAR). This means 13.3 cases/10.000 NB versusu the estimated incidence of 2 cases/10.000 NB. This accumulation of defects can not be due to chance, so we have decided to focus on its research.
  
  
  METHODS
  The study included all the patients with anorrectal malformations born in 2011. In all of them we analyzed: geographic area, age and health status of parents, pregnancy, exposure to teratogens, especially lorazepam intake, sex, gestational age, weight at birth, exploration of the abdomen and perineum, birth defects associated, imaging studies performed, treatment and current situation.
  
  
  RESULTS
  All patients came from our province, and maternal age is under 20 years in 2 patientes and older than 30 in 7; male-dominated (8/1); low forms in 4 of 9 patients. 100% of newborns have some type of associated malformation, in genitals, urinary system or costovertebral. Clinical assessment and imaging study provided the right diagnosis in all the cases. It must be noted the absence of difficulties in the surgery treatment and a favorable outcome in all children.
  
  
  CONCLUSIONS
  To this accumulation of cases with anorrectal malformation cases it is added a male predominanced, and a high incidence of associatedmalformations and high defects. We have not found an epidemiological explanation for this concentration of patients with anorrectal malformations. This forces us to continue our investigation if detected for some reason, currently not known.
authors: Hospital Materno-lnfantil Infanta Cristina, SES, UEX, Grupo de Investigación en Pediatría PAIDOS (CTS 019), Badajoz. cmorenohurtado@yahoo.com
authors: C
authors: C
authors: Moreno Hurtado
authors: S
authors: S
authors: Amat Valero
authors: N
authors: N
authors: Fuentes Bolaño
authors: R
authors: R
authors: Núñez Núñez
authors: E
authors: E
authors: Blesa Sánchez
authors: R
authors: R
authors: Cavaco Fernandes
mesh_terms: D000015:Abnormalities, Multiple / Q000453:epidemiology* / Q000209:etiology; D001003:Anal Canal / Q000002:abnormalities*; D000013:Congenital Abnormalities / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D012007:Rectum / Q000002:abnormalities*