title: Metabolism of pyrene, a polycyclic aromatic hydrocarbon in freshwater turtles.
abstract: Reptile population decrease is an alarming trend all around the world. Yet little is known about the role of xenobiotics in this decrease. In this study, we investigated the metabolism of pyrene in three freshwater turtle species (Red-EARED sliders (Trachemys scripta elegans), Chinese pond turtles (Mauremys reevesii) and Chinese softshell turtles (Pelodiscus sinensis). Compared to other vertebrates, all turtles showed an unique metabolite distribution, pyrene-1-sulfate being the main metabolite. The observed low phase II enzyme metabolic rates raises the question of the effect of long-time exposure.
authors: Laboratory of Toxicology, Graduate School of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita-ku, Sapporo 060-0818, Japan.
authors: Balazs
authors: B
authors: Oroszlany
authors: Yoshinori
authors: Y
authors: Ikenaka
authors: Aksorn
authors: A
authors: Saengtiengchan
authors: Mami
authors: M
authors: Oguri
authors: Shouta M M
authors: SM
authors: Nakayama
authors: Mayumi
authors: M
authors: Ishizuka
mesh_terms: D000818:Animals; D005456:Fluorescent Dyes / Q000737:chemistry / Q000378:metabolism*; D011721:Pyrenes / Q000737:chemistry / Q000378:metabolism*; D013045:Species Specificity; D014426:Turtles / Q000145:classification / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000378:metabolism*
chemical_list: D005456:Fluorescent Dyes; D011721:Pyrenes; D014874:Water Pollutants, Chemical; C030984:pyrene