title: Total synthesis of (±)-δ-rubromycin.
abstract: Transition-metal-catalyzed spiroketalization cyclization has been performed successfully and has led to the first total synthesis of (±)-δ-rubromycin with a longest linear sequence of 18 steps from commercially available guaiacol in a 2.7% overall yield.
authors: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou 730000, Gansu, P. R. China.
authors: Wenjing
authors: W
authors: Wang
authors: Jijun
authors: J
authors: Xue
authors: Tian
authors: T
authors: Tian
authors: Jie
authors: J
authors: Zhang
authors: Liping
authors: L
authors: Wei
authors: Jidong
authors: J
authors: Shao
authors: Zhixiang
authors: Z
authors: Xie
authors: Ying
authors: Y
authors: Li
mesh_terms: D002384:Catalysis; D003500:Cyclization; D006139:Guaiacol / Q000737:chemistry*; D015394:Molecular Structure; D011809:Quinones / Q000138:chemical synthesis* / Q000737:chemistry; D013141:Spiro Compounds / Q000737:chemistry*; D013237:Stereoisomerism; D028561:Transition Elements / Q000737:chemistry*
chemical_list: D011809:Quinones; D013141:Spiro Compounds; D028561:Transition Elements; C064949:gamma-rubromycin; D006139:Guaiacol