title: Endothelium and regulatory inflammatory mechanisms during organ rejection.
abstract: Endothelial integrity is mandatory for physiologic organ function; however, endothelium dysfunction can be caused by systemic inflammation, occurring during sepsis or organ rejection after transplantation. This article will address our current understanding of endothelial involvement in organ transplantation and rejection. Overall, more detailed studies focusing on the endothelial modulation after organ transplantation would be necessary to investigate the role of endothelium activation during organ rejection.
authors: 1Department of Intensive Care Route de Lennik, Erasme Hospital, Université Libre de Bruxelles, 1070 Bruxelles, Belgium.
authors: Fabio Silvio
authors: FS
authors: Taccone
authors: Ettore
authors: E
authors: Crimi
authors: James
authors: J
authors: Anstey
authors: Teresa
authors: T
authors: Infante
authors: Katia
authors: K
authors: Donadello
authors: Sabino
authors: S
authors: Scolletta
authors: Mohammed
authors: M
authors: Al-Omran
authors: Claudio
authors: C
authors: Napoli
mesh_terms: D000818:Animals; D004730:Endothelium, Vascular / Q000276:immunology* / Q000503:physiopathology; D006084:Graft Rejection / Q000276:immunology* / Q000503:physiopathology; D006801:Humans; D007249:Inflammation / Q000276:immunology* / Q000503:physiopathology; D018836:Inflammation Mediators / Q000378:metabolism; D016377:Organ Transplantation / Q000009:adverse effects*; D015398:Signal Transduction
chemical_list: D018836:Inflammation Mediators
keywords: dysfunction; endothelium; inflammation; organ rejection